Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria "Intracellular and membrane" No No 71000 "Cluster 46: Basophils - DNA binding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA036991: AB_2675420, HPA036992: AB_10672345, HPA066081: AB_2685610" "unprognostic (1.65e-1)" "prognostic favorable (7.57e-4)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (1.14e-1)" "unprognostic (8.50e-2)" "unprognostic (1.69e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-2)" "prognostic favorable (4.72e-9)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (4.18e-3)" "unprognostic (2.76e-2)" 11.0 21.9 23.0 10.6 25.3 10.9 15.0 24.5 29.3 11.3 22.9 14.1 11.7 11.1 50.8 8.2 14.9 10.1 25.0 23.9 24.6 49.4 34.4 10.1 17.9 23.5 23.2 19.8 13.7 16.7 27.9 10.8 23.7 20.4 14.7 27.0 25.5 13.7 14.1 10.0 10.3 10.0 24.4 14.6 14.9 16.4 26.3 21.8 31.1 19.6 16.2 9.5 8.3 25.3 40.2 34.1 36.4 12.0 20.5 27.5 19.8 41.4 21.5 33.0 31.7 35.3 22.4 36.0 22.6 17.2 22.7 21.6 16.3 23.0 44.9 12.1 20.6 29.7 15.4 30.7 16.3 60.3 30.4 16.9 16.7 17.0 42.4 22.7 35.9 42.1 13.9 14.9 36.7 13.7 56.9 27.9 23.7 43.8 53.2 50.9 23.4 16.7 34.6 17.1 24.6 17.9 33.2 23.7 39.8 14.3 26.8 21.8 20.6 19.7 25.3 14.4 21.7 23.6 9.0 61.4 20.1 32.4 21.5 29.4 16.5 25.2 9.8 21.6 16.8 26.2 12.2 11.3 28.1 21.6 15.4 13.9 2.5 11.4 17.3 17.8 13.2 16.1 23.0 25.3 24.5 29.3 23.9 24.6 23.5 23.2 23.7 24.4 26.3 25.3 9.1 0.0 7.2 11.1 19.7 7.0 10.2 12.1 14.2 21.8 12.7 10.9 26.1 7.2 12.4 11.0 8.4 19.2 16.1 7.0 35.2 5.2 1.0 11.1 10.3 8.8 12.1 24.2 16.0 7.8 14.9 12.3 12.8 6.8 9.5 9.5 10.0 26.2 14.1 42.1 16.2 13.4 6.1 19.5 7.0 3.0 10.5 11.0 10.6 15.0 10.7 20.4 12.3 14.6 15.6 5.4 4.0 7.5 25.0 5.1 7.0 42.5 19.5 16.2 0.0 7.9 8.9 29.7 37.0 13.6 8.2 5.5 14.6 19.2 12.1 4.5 ABHD4 FLJ12816 ENSG00000100439 "Abhydrolase domain containing 4, N-acyl phospholipase B" Q8TB40 14 22598237-22613215 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 35.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 35.4" "Cell line enhanced" "Detected in many" "ASC diff: 121.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000600 Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA000600: AB_1078081" "unprognostic (5.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.68e-3)" "unprognostic (8.17e-2)" "unprognostic (1.17e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-3)" "unprognostic (3.69e-2)" "unprognostic (1.28e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.73e-1)" "unprognostic (1.56e-2)" "unprognostic (5.18e-2)" "unprognostic (1.37e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" 22.8 28.7 21.6 7.3 23.6 12.6 17.5 22.3 22.4 25.9 27.7 19.2 15.0 26.3 27.4 38.3 15.4 24.7 20.5 21.0 24.5 25.3 22.6 17.6 8.0 27.8 24.5 15.9 14.5 22.8 12.8 17.9 23.3 19.3 13.8 21.7 16.5 33.7 25.5 18.9 17.9 24.5 22.5 14.8 24.9 36.8 24.2 10.1 21.6 27.2 14.8 24.8 26.2 26.0 23.4 38.5 15.5 14.2 121.8 44.0 14.9 10.3 52.2 25.3 46.8 23.5 36.4 2.2 26.7 45.2 27.2 44.5 9.9 26.6 20.6 17.3 3.5 8.7 28.1 77.9 55.6 1.4 30.3 56.1 20.6 33.2 28.2 52.7 26.4 16.0 6.5 41.1 23.5 12.8 0.7 1.3 18.8 94.4 27.7 6.5 13.8 9.8 29.6 24.6 1.0 3.1 69.1 24.3 27.2 30.6 9.5 2.6 18.8 11.0 14.9 18.0 4.1 44.1 25.3 0.8 8.2 1.8 8.9 35.4 6.3 10.2 8.2 4.7 6.8 5.5 5.4 5.5 4.2 3.1 1.7 3.5 25.7 7.3 4.6 0.6 3.4 5.6 21.6 23.6 22.3 22.4 21.0 24.5 27.8 24.5 23.3 22.5 24.2 26.0 5.0 12.8 5.6 2.6 4.7 3.2 7.0 5.2 7.4 3.5 6.2 6.6 6.7 11.5 3.4 3.7 4.2 6.1 4.8 9.8 9.8 13.3 3.1 8.3 6.0 6.5 6.0 4.4 1.1 11.7 2.3 5.2 16.3 12.5 5.1 5.2 9.3 10.3 7.8 8.4 1.2 6.8 4.1 6.9 1.7 4.7 5.6 4.6 1.8 1.0 9.4 6.9 5.2 4.0 3.7 9.8 9.3 8.2 12.4 9.5 13.3 4.7 2.6 3.2 6.6 3.1 6.0 0.7 0.5 13.2 2.7 26.8 5.0 9.7 3.3 11.7 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.3;skeletal muscle: 380.0;tongue: 475.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 373.1;Distal tubular cells: 344.4;Hepatocytes: 261.2;Proximal tubular cells: 564.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 289.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006198, HPA026542" Enhanced Enhanced Mitochondria NA NA 930000 "Cluster 19: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA006198: AB_1078087, HPA026542: AB_1844469" "unprognostic (9.04e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.30e-4)" "unprognostic (5.09e-3)" "unprognostic (1.61e-3)" "unprognostic (5.68e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (4.95e-2)" "unprognostic (9.40e-3)" "unprognostic (3.35e-1)" "prognostic favorable (3.83e-8)" "unprognostic (1.27e-1)" "unprognostic (4.09e-2)" "unprognostic (3.56e-2)" "unprognostic (1.24e-1)" 81.9 82.2 25.2 24.3 25.0 17.3 69.9 26.6 42.2 29.3 30.4 46.8 103.9 20.0 25.3 51.3 30.6 27.8 217.8 24.3 25.9 295.9 367.3 22.6 42.6 26.9 26.8 35.7 35.9 66.3 19.2 16.9 25.8 26.8 49.5 21.2 31.4 26.2 380.0 14.4 75.6 25.5 26.2 27.4 52.8 35.7 25.8 29.7 38.4 475.9 44.3 32.7 21.3 25.2 25.8 20.5 61.0 26.8 53.1 42.1 17.5 48.1 40.4 46.1 38.5 38.3 39.5 289.1 40.7 34.4 39.0 22.8 54.9 41.8 57.8 113.0 25.5 94.4 58.5 58.3 36.4 80.0 23.9 50.7 23.5 39.8 22.8 35.0 36.2 56.6 102.3 60.4 50.5 9.6 96.3 40.6 50.2 80.4 49.5 118.8 83.8 30.6 77.9 70.7 33.8 43.0 38.0 111.6 102.0 43.1 32.7 107.6 20.2 29.9 29.6 26.6 78.1 38.6 62.0 128.1 25.8 67.0 35.3 15.3 14.2 19.3 17.1 20.9 27.3 40.7 17.8 21.5 21.4 24.6 20.3 23.6 0.5 25.0 20.4 23.2 19.5 19.5 25.2 25.0 26.6 42.2 24.3 25.9 26.9 26.8 25.8 26.2 25.8 25.2 42.9 57.7 58.3 29.7 56.5 27.3 41.8 69.0 44.3 39.0 49.0 40.9 373.1 52.9 63.0 58.8 25.0 35.8 39.4 42.6 344.4 37.9 55.4 27.1 32.2 36.2 40.7 67.6 51.6 26.5 19.5 47.6 26.0 25.4 44.9 61.5 43.9 261.2 75.7 30.3 46.7 38.7 63.1 45.6 22.2 24.4 46.9 38.2 51.6 19.7 32.8 53.7 29.9 36.2 36.0 21.2 49.7 45.5 74.9 24.2 88.0 564.8 106.7 30.0 0.0 38.6 43.7 76.3 86.1 46.6 27.0 15.3 39.4 72.5 46.7 35.9 ACAP1 "CENTB1, KIAA0050" ENSG00000072818 "ArfGAP with coiled-coil, ankyrin repeat and PH domains 1" Q15027 17 7336529-7351477 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.0;intestine: 43.3;lymphoid tissue: 96.0" "Cell type enriched" "Detected in many" 6 "Late spermatids: 3430.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.3;HDLM-2: 31.0;JURKAT: 42.4;Karpas-707: 29.4;NB-4: 37.9;U-937: 24.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075570 Approved Approved "Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA075570: AB_2732295" "unprognostic (1.20e-2)" "prognostic favorable (3.66e-4)" "unprognostic (2.49e-1)" "prognostic favorable (2.97e-5)" "unprognostic (4.43e-4)" "prognostic favorable (4.17e-5)" "unprognostic (5.66e-3)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.65e-10)" "unprognostic (1.14e-1)" "unprognostic (5.58e-2)" "unprognostic (2.90e-1)" "unprognostic (8.61e-3)" 5.6 1.1 0.4 18.9 0.5 41.0 2.1 0.5 0.8 2.3 0.5 7.4 4.1 1.5 0.3 4.2 4.0 3.6 2.1 0.3 0.4 4.6 5.2 16.1 39.5 0.6 0.5 0.9 1.2 0.1 1.3 0.5 0.6 3.8 2.1 0.2 3.6 0.4 0.9 2.5 43.3 0.9 0.5 96.0 5.0 0.8 0.8 25.8 5.2 0.8 22.6 4.3 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.1 0.0 23.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 8.8 0.1 0.0 0.1 11.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 42.4 0.0 29.4 0.0 0.0 14.5 37.9 0.4 0.0 0.0 15.1 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.9 0.0 0.0 0.1 0.0 0.0 9.1 8.2 10.9 0.1 24.9 0.0 28.8 7.9 30.8 29.6 2.4 33.3 20.2 31.5 32.1 13.7 21.3 26.7 27.5 22.6 32.5 0.4 17.3 39.0 22.3 0.4 0.5 0.5 0.8 0.3 0.4 0.6 0.5 0.6 0.5 0.8 0.6 3.8 9.6 5.5 1.6 150.9 8.3 7.6 25.1 2.8 15.8 7.0 8.1 32.9 7.2 12.3 5.5 18.8 3.9 160.7 2.0 7.9 3.9 498.1 8.3 5.4 5.0 3.6 22.9 0.3 3.7 3.2 8.0 5.6 3.4 40.5 1.8 7.1 5.3 7.5 0.0 1.9 2.7 8.2 26.2 39.5 3430.7 20.2 27.9 24.9 2.8 38.3 11.7 332.7 0.5 1.0 5.5 0.0 15.4 68.0 4.6 1.3 3.8 44.6 20.4 19.7 7.5 8.1 15.6 10.5 1.5 7.4 4.4 268.3 0.9 1.6 3.5 ACBD5 "DKFZp434A2417, KIAA1996" ENSG00000107897 "Acyl-CoA binding domain containing 5" Q5T8D3 10 27168135-27243046 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Transport" Leukodystrophy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011861, HPA012145" Enhanced Enhanced Peroxisomes NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" Peroxisomes "HPA011861: AB_1844493, HPA012145: AB_1844494" "prognostic unfavorable (3.33e-4)" "unprognostic (4.93e-1)" "unprognostic (3.68e-1)" "unprognostic (1.34e-1)" "unprognostic (6.21e-2)" "unprognostic (5.98e-3)" "unprognostic (9.87e-2)" "unprognostic (3.42e-2)" "unprognostic (2.69e-1)" "unprognostic (3.66e-1)" "unprognostic (1.11e-1)" "unprognostic (4.46e-2)" "prognostic favorable (4.68e-5)" "unprognostic (7.91e-3)" "unprognostic (1.71e-1)" "unprognostic (3.63e-2)" "unprognostic (3.37e-3)" 14.6 25.1 31.0 13.5 37.0 18.2 12.3 36.2 37.1 13.2 24.2 20.3 39.8 9.4 9.7 12.0 12.0 15.4 40.4 27.6 33.1 37.3 73.8 14.7 14.7 37.2 34.0 9.9 11.1 31.2 6.4 13.4 38.1 15.2 20.9 36.2 10.3 11.4 31.0 17.3 39.2 8.8 36.7 14.7 21.0 19.3 36.1 12.2 27.8 36.6 12.7 13.5 7.5 38.8 25.8 76.5 17.1 18.0 19.1 17.3 20.1 32.3 12.1 28.1 33.5 19.4 39.9 10.7 27.0 22.4 23.4 21.1 23.2 16.3 23.0 26.2 23.9 16.5 23.1 15.2 20.6 11.0 20.9 16.7 17.7 23.5 12.8 24.9 20.5 16.7 13.6 19.5 35.7 20.0 21.1 9.4 13.1 35.2 10.0 17.4 42.5 20.2 44.1 22.4 21.3 45.5 35.4 38.3 17.9 18.9 18.8 11.5 30.4 27.2 15.2 43.7 25.9 19.4 28.1 20.7 27.4 24.6 12.0 12.5 13.0 10.2 15.3 12.7 15.2 6.4 7.5 12.4 13.0 7.0 5.0 11.0 11.1 10.3 15.1 8.5 7.4 8.0 31.0 37.0 36.2 37.1 27.6 33.1 37.2 34.0 38.1 36.7 36.1 38.8 23.3 25.6 29.9 17.9 16.0 9.7 4.1 14.5 7.4 30.8 14.5 10.8 83.0 15.7 25.2 31.3 25.0 9.6 27.4 22.4 33.2 22.1 43.1 33.7 20.2 18.7 10.2 8.6 20.6 16.2 12.6 16.4 19.4 41.1 12.6 11.5 12.8 56.9 19.0 23.5 26.9 30.4 10.2 25.5 12.5 16.9 16.4 22.4 21.4 15.9 22.4 47.7 29.9 17.6 24.8 17.8 26.1 16.6 14.2 11.7 64.4 48.2 32.7 47.2 19.7 20.9 16.1 41.0 8.3 16.5 15.5 10.4 22.3 27.1 26.5 9.2 ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 847.1;Proximal tubular cells: 525.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" 6.3 6.1 7.2 4.8 7.5 3.4 3.8 7.9 7.3 3.4 6.0 9.1 6.5 3.1 3.7 3.4 3.6 4.9 12.0 6.6 7.8 19.2 30.6 4.6 5.2 7.2 7.8 3.9 6.6 7.2 5.1 3.0 7.4 6.5 7.4 9.6 5.0 3.3 12.2 5.5 6.1 3.1 7.1 4.8 5.5 7.0 8.2 5.1 5.7 10.3 3.4 3.5 3.1 7.4 5.9 7.6 7.6 13.6 10.5 13.1 4.2 4.8 5.8 3.5 5.4 10.1 7.5 11.1 16.2 5.5 18.4 6.4 6.7 9.7 5.4 17.4 6.2 10.4 7.7 7.0 5.3 6.7 4.6 7.6 9.4 4.7 9.0 8.5 8.3 11.3 17.0 5.7 7.0 6.1 12.1 12.9 5.1 11.7 5.9 10.4 6.6 14.0 11.7 5.4 15.0 5.2 5.7 19.1 14.1 8.8 13.2 5.5 9.7 6.2 3.5 1.7 4.6 10.7 29.3 11.1 6.5 23.8 19.1 4.8 5.3 3.6 4.4 5.7 6.1 6.9 4.9 5.0 4.7 4.9 5.7 5.1 6.2 4.6 5.8 3.7 5.3 4.8 7.2 7.5 7.9 7.3 6.6 7.8 7.2 7.8 7.4 7.1 8.2 7.4 27.9 67.3 41.7 19.6 19.7 17.2 26.6 66.4 18.8 18.7 29.4 32.3 94.6 45.8 46.9 31.3 16.7 56.8 22.6 88.4 158.5 43.2 847.1 34.0 31.3 24.0 54.7 37.2 12.1 40.2 31.1 26.2 23.9 31.8 14.5 30.3 21.4 215.5 86.7 5.0 14.3 85.8 67.1 24.5 23.7 131.5 19.6 35.0 26.6 14.0 68.9 41.7 18.6 15.6 18.7 29.2 130.7 24.0 25.4 23.2 47.1 525.2 56.8 31.8 26.3 50.6 64.2 117.1 27.3 19.5 23.4 40.0 20.5 43.4 69.4 28.6 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 1061.1;Late spermatids: 2128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 2000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 41.2 104.0 43.1 45.5 47.6 91.9 64.7 43.9 54.0 43.4 63.9 61.4 64.0 46.6 69.3 43.3 57.9 45.4 57.3 49.4 47.1 78.1 106.4 46.8 66.2 43.4 44.2 59.2 94.1 73.9 59.2 61.7 44.3 52.1 64.7 72.7 71.1 44.2 76.6 41.3 60.7 41.5 44.9 44.7 67.1 46.1 45.3 66.2 63.7 74.9 61.9 47.5 36.4 50.2 78.3 112.5 177.4 97.4 76.1 77.1 142.2 92.6 97.7 91.9 80.8 151.7 78.5 48.8 70.7 85.1 114.6 76.5 169.4 97.0 82.3 118.7 157.9 142.3 99.0 348.5 105.7 162.5 80.4 78.7 90.5 81.9 102.3 95.5 105.8 176.9 145.1 95.1 110.9 103.1 178.5 161.3 214.1 204.7 111.7 118.2 176.1 114.5 144.2 110.5 191.6 191.3 56.0 137.6 196.3 115.0 82.1 89.8 88.9 101.3 65.2 84.0 142.6 123.8 261.2 150.4 120.0 138.9 123.7 65.4 61.6 57.2 88.8 75.2 118.1 106.6 100.4 103.2 57.3 97.2 118.1 115.2 10.9 121.5 80.2 65.3 117.6 115.0 43.1 47.6 43.9 54.0 49.4 47.1 43.4 44.2 44.3 44.9 45.3 50.2 62.5 44.8 96.7 9.1 102.6 79.2 105.3 173.4 51.8 53.1 118.8 130.0 84.9 131.5 119.6 68.0 8.4 207.1 101.3 81.9 270.1 226.7 1061.1 113.1 56.2 70.6 82.5 291.5 20.4 169.0 279.7 74.2 54.6 85.5 70.3 95.9 56.0 115.8 141.1 28.6 21.0 125.1 126.1 72.0 66.3 2128.2 94.4 74.6 81.8 16.9 117.8 92.2 152.4 19.6 26.0 174.4 109.2 92.2 106.4 187.0 174.2 306.6 128.1 56.9 92.1 42.5 87.0 122.6 137.4 87.4 91.2 187.7 86.0 124.4 143.9 148.3 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 ACTA2 ACTSA ENSG00000107796 "Actin alpha 2, smooth muscle" P62736 10 88935074-88991339 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 6678.8;seminal vesicle: 5920.3;smooth muscle: 8099.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1007.7;Peritubular cells: 5290.7;Sertoli cells: 3030.6;Smooth muscle cells: 2394.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 58.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 390.6;fHDF/TERT166: 641.1;HHSteC: 625.8;HSkMC: 345.1;hTERT-RPE1: 743.4;SuSa: 296.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 101.0" "CAB000002, CAB003761, CAB013531, HPA041264, HPA041271" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "CAB000002: AB_2223500, CAB003761: AB_562031, CAB013531: , HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (7.05e-2)" "unprognostic (2.54e-1)" "unprognostic (2.30e-3)" "unprognostic (3.18e-2)" "unprognostic (3.33e-2)" "unprognostic (6.19e-2)" "unprognostic (2.36e-2)" "unprognostic (1.71e-2)" "unprognostic (4.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.44e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (1.37e-8)" "unprognostic (1.87e-3)" "unprognostic (2.30e-1)" "unprognostic (7.91e-2)" "unprognostic (2.09e-3)" 1035.2 241.6 54.0 728.1 61.4 3.9 838.4 52.7 121.1 2000.3 61.4 2755.1 248.9 6678.8 1360.1 1509.9 3104.3 906.1 1069.2 53.4 54.6 312.2 161.8 732.8 173.7 59.0 55.9 798.0 91.4 80.6 60.8 771.3 55.3 2642.8 866.4 8.2 414.7 5920.3 202.1 355.7 701.6 8099.9 54.1 452.1 1427.1 263.9 56.1 56.5 312.0 214.0 48.4 3002.5 1367.0 52.9 3.9 19.0 49.3 102.7 198.1 390.6 9.5 109.8 136.8 11.9 45.4 0.0 8.8 7.2 11.5 641.1 8.6 1.4 1.8 25.4 11.3 60.6 11.3 0.4 5.6 119.3 625.8 0.8 3.2 345.1 44.9 73.9 28.5 743.4 11.3 3.0 0.0 7.1 128.8 10.8 1.0 28.3 2.5 0.2 1.2 1.4 0.2 4.6 27.1 5.0 0.7 7.6 10.2 7.9 1.0 296.8 32.4 1.0 27.9 24.0 4.0 30.2 9.3 21.1 1.6 0.6 29.6 10.2 26.1 28.1 12.3 17.5 17.6 8.7 13.8 6.0 14.1 19.8 10.8 1.8 1.5 10.7 11.1 4.0 14.2 0.4 58.7 10.7 54.0 61.4 52.7 121.1 53.4 54.6 59.0 55.9 55.3 54.1 56.1 52.9 65.4 9.6 6.1 5.5 4.4 43.2 23.4 16.5 22.8 1.1 22.7 1007.7 25.1 2.8 5.2 0.0 6.2 16.3 7.3 1.9 1.9 1.8 11.1 11.1 225.4 41.1 0.0 4.0 3.6 0.9 16.8 316.3 10.7 8.2 5.7 448.9 474.0 4.6 37.7 0.0 1.1 2.7 4.1 5.4 67.6 48.8 141.4 12.6 55.2 61.8 4.2 13.4 4.1 1.0 0.3 2.0 3.0 5290.7 3.7 17.5 3.4 9.5 10.9 1.4 3030.6 72.0 2394.6 4.0 13.8 11.1 40.5 23.7 16.5 36.0 5.7 10.4 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 ACTL6B "ACTL6, BAF53B" ENSG00000077080 "Actin like 6B" O94805 7 100643097-100656448 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 20.7;pituitary gland: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.0;Excitatory neurons: 22.1;Horizontal cells: 6.7;Inhibitory neurons: 19.0" "Group enriched" "Detected in some" 11 "glioma: 3.9;pancreatic cancer: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 76 "SCLC-21H: 28.5;SH-SY5Y: 28.7" "Low region specificity" "Detected in all" HPA045126 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli rim, Mitotic chromosome" "HPA045126: AB_10961265" "unprognostic (3.31e-2)" "unprognostic (6.89e-2)" "unprognostic (4.59e-3)" "unprognostic (4.15e-2)" "unprognostic (1.27e-3)" "unprognostic (4.81e-3)" "unprognostic (6.00e-2)" "unprognostic (8.26e-3)" "unprognostic (1.29e-1)" "unprognostic (4.72e-3)" "unprognostic (1.28e-1)" "unprognostic (3.01e-4)" "unprognostic (1.64e-1)" "unprognostic (6.84e-2)" "unprognostic (2.01e-2)" 0.0 1.8 13.8 0.0 14.5 0.0 0.0 9.4 20.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.9 8.5 0.0 0.0 0.0 0.0 4.4 1.8 0.0 0.8 0.1 15.3 0.0 4.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.5 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 28.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 14.5 9.4 20.7 14.9 8.5 4.4 1.8 4.3 1.7 3.9 11.5 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 8.0 0.0 0.1 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 22.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 19.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 1.0 0.0 1.2 0.0 3.5 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 ACTR3C ARP11 ENSG00000106526 "Actin related protein 3C" Q9C0K3 7 150243916-150323725 "Predicted intracellular proteins" Actin-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "parathyroid gland: 64.1" "Group enriched" "Detected in many" 5 "Astrocytes: 87.1;Excitatory neurons: 111.7;Inhibitory neurons: 125.4;Oligodendrocyte precursor cells: 275.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 31.1;RT4: 26.7;SiHa: 17.8" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (3.41e-1)" "unprognostic (4.79e-2)" "unprognostic (9.62e-2)" "unprognostic (8.25e-2)" "unprognostic (6.07e-6)" "unprognostic (2.83e-1)" "unprognostic (6.81e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-2)" "unprognostic (2.91e-1)" "unprognostic (9.69e-3)" "unprognostic (1.65e-2)" "unprognostic (3.27e-2)" "unprognostic (4.73e-3)" "unprognostic (1.72e-1)" "unprognostic (9.14e-2)" "unprognostic (5.53e-3)" 2.2 11.9 3.5 3.4 4.5 1.9 6.2 2.9 3.9 5.2 24.3 5.2 5.2 2.5 7.0 7.1 5.4 4.3 2.0 5.3 3.3 13.2 22.9 5.1 4.1 3.1 3.3 1.5 14.5 64.1 5.3 2.2 3.3 4.3 6.9 4.7 4.8 5.4 1.4 2.6 4.1 2.6 1.9 1.8 4.9 4.1 3.2 2.5 6.0 2.8 5.9 4.9 3.2 2.3 6.7 0.6 0.1 0.2 0.0 0.0 1.1 0.1 0.2 1.1 1.4 5.1 31.1 2.5 8.1 1.2 0.8 13.3 0.0 0.0 0.7 7.1 1.9 1.7 7.5 4.7 3.3 0.0 1.1 1.2 4.2 0.0 0.0 0.8 0.3 3.2 13.2 7.1 0.0 9.4 7.1 0.3 3.5 4.5 0.0 0.0 4.9 10.1 5.1 26.7 6.7 5.4 17.8 3.8 2.7 1.0 8.4 1.6 0.1 0.0 0.0 0.2 0.1 2.5 3.4 0.0 0.2 0.1 0.0 0.3 1.1 2.2 4.9 0.9 2.2 3.4 4.0 3.0 1.7 4.6 4.2 3.4 1.7 3.2 0.5 3.0 3.4 1.3 3.5 4.5 2.9 3.9 5.3 3.3 3.1 3.3 3.3 1.9 3.2 2.3 0.2 3.2 9.5 87.1 3.8 20.1 7.6 5.5 6.8 7.3 4.3 2.4 2.1 7.2 6.4 18.4 29.2 5.6 2.0 7.1 13.7 12.6 4.2 11.7 1.3 1.4 3.5 4.0 111.7 21.3 1.0 1.3 9.7 6.9 11.4 3.4 1.8 20.8 1.2 1.7 125.4 5.1 16.2 1.0 2.8 1.2 0.9 1.2 1.8 9.4 4.6 15.9 7.2 275.5 11.7 11.3 1.3 0.7 6.2 4.8 11.0 14.8 11.1 6.3 0.0 5.0 1.0 6.7 2.8 5.3 14.9 7.1 4.1 2.5 5.7 6.1 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 ACY1 ENSG00000243989 "Aminoacylase 1" Q03154 3 51983340-51989197 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "intestine: 181.5;kidney: 449.9;liver: 274.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 31.6;Gastric mucus-secreting cells: 32.6;Proximal enterocytes: 144.8;Proximal tubular cells: 92.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 128.0" "CAB003695, HPA036174, HPA036175" Enhanced NA NA 23000000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB003695: AB_425286, HPA036174: AB_2674988, HPA036175: AB_2674989" "unprognostic (4.28e-2)" "unprognostic (1.89e-1)" "unprognostic (2.10e-1)" "unprognostic (2.48e-3)" "unprognostic (3.15e-1)" "unprognostic (6.51e-2)" "unprognostic (2.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.08e-2)" "unprognostic (2.36e-2)" "unprognostic (2.70e-2)" "prognostic favorable (2.93e-4)" "unprognostic (3.57e-1)" "unprognostic (3.75e-1)" "unprognostic (7.88e-2)" "prognostic favorable (6.77e-4)" 19.2 24.0 5.6 7.3 5.7 8.8 20.7 6.4 7.3 13.9 11.6 30.6 181.5 4.3 21.8 10.7 13.0 10.7 14.5 5.1 6.0 449.9 274.9 9.2 7.2 6.5 5.9 4.8 8.7 28.2 4.7 9.7 6.6 14.3 30.5 1.9 16.4 11.1 20.2 8.2 138.2 6.9 6.7 8.1 23.6 3.2 6.1 5.1 21.0 34.6 9.2 12.5 7.1 6.6 15.9 26.2 13.2 34.1 28.9 39.4 40.5 12.6 28.2 29.4 14.9 41.2 67.9 7.2 12.2 22.0 13.2 20.0 14.7 81.2 11.5 21.8 10.7 25.3 13.9 128.0 49.7 19.8 21.0 48.0 67.2 25.4 69.1 25.8 11.5 14.6 47.1 23.9 29.9 35.2 0.6 38.9 23.4 92.1 39.3 8.0 14.1 63.5 74.5 50.8 16.9 18.2 12.6 62.6 29.5 7.5 42.3 27.9 7.1 22.0 21.9 24.8 18.8 61.7 16.9 12.1 28.1 42.9 29.0 9.1 15.7 0.4 10.7 15.1 5.7 7.4 2.6 4.5 21.2 6.1 4.1 4.7 0.0 20.4 6.4 2.8 3.8 9.7 5.6 5.7 6.4 7.3 5.1 6.0 6.5 5.9 6.6 6.7 6.1 6.6 0.5 3.2 3.2 0.0 4.9 0.6 1.0 1.9 17.1 0.2 2.7 1.3 0.2 1.5 2.5 5.5 0.0 3.9 0.3 31.6 9.8 16.6 0.2 0.2 0.9 0.9 2.4 15.8 0.0 8.3 4.5 4.3 32.6 0.6 7.0 0.2 1.1 13.1 1.9 0.0 0.0 11.2 4.1 1.9 0.3 0.8 0.6 4.2 0.0 0.0 9.3 0.8 1.0 0.0 0.0 16.4 23.3 0.0 14.9 0.6 144.8 92.0 1.7 1.1 0.0 0.6 2.0 0.1 0.2 18.5 0.4 4.1 2.6 1.0 14.5 0.4 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 97.7;heart muscle: 105.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Inhibitory neurons: 44.0;Oligodendrocytes: 89.7;Paneth cells: 59.6;Peritubular cells: 73.7;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 15.5;RPMI-8226: 2.7;RPTEC TERT1: 5.2" "Region enriched" "Detected in all" 5 "basal ganglia: 388.0" "Region enriched" "Detected in all" 6 "basal ganglia: 155.9" "HPA017730, HPA077682" Uncertain Enhanced "Intermediate filaments" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "HPA017730: AB_1844595, HPA077682: AB_2686851" "unprognostic (3.55e-2)" "unprognostic (1.01e-3)" "unprognostic (7.61e-3)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.26e-2)" "unprognostic (1.48e-1)" "unprognostic (7.61e-2)" "unprognostic (2.49e-2)" "unprognostic (2.34e-1)" "unprognostic (7.27e-3)" "unprognostic (2.64e-2)" "prognostic favorable (7.46e-6)" "unprognostic (1.81e-2)" "unprognostic (5.65e-2)" "unprognostic (3.19e-2)" "unprognostic (5.97e-4)" 18.9 3.3 25.5 4.9 97.7 0.0 10.6 13.9 43.9 9.8 0.0 35.1 5.2 14.7 5.7 18.8 12.7 10.0 105.2 25.8 15.9 12.8 3.3 4.1 2.3 20.5 18.3 13.2 7.5 0.8 14.3 6.1 17.4 19.8 5.6 4.5 4.0 21.5 2.7 2.6 13.0 18.2 10.8 6.5 21.2 8.2 34.4 1.3 1.9 5.8 3.0 23.2 7.8 30.1 0.0 0.6 1.3 0.1 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.2 2.3 0.5 0.6 0.0 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 15.5 0.0 0.0 0.8 0.0 0.1 0.0 0.3 2.7 5.2 0.5 1.8 1.6 0.0 0.5 0.1 1.7 0.0 0.1 0.0 0.1 1.2 0.1 0.2 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 97.7 13.9 43.9 25.8 15.9 20.5 18.3 17.4 10.8 34.4 30.1 0.3 0.0 0.0 8.1 0.1 0.3 0.1 0.2 0.0 21.8 0.4 5.8 75.5 8.6 0.0 7.3 0.0 1.4 0.0 2.6 0.0 15.9 0.9 1.5 7.1 1.8 0.0 0.0 34.0 6.9 4.0 5.2 0.0 4.0 0.0 4.6 3.9 0.1 0.3 0.0 44.0 0.3 0.0 0.0 0.3 3.0 20.5 0.1 0.0 6.5 1.0 1.0 0.0 19.1 89.7 0.4 59.6 73.7 0.0 0.1 0.3 0.8 0.0 2.2 65.7 0.6 21.4 0.8 6.3 0.2 0.9 12.4 0.2 1.0 2.0 0.1 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 245.3;Inhibitory neurons: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 920000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: " "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.93e-4)" "prognostic favorable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 23.9 15.5 13.0 16.9 18.7 28.6 27.4 13.5 17.7 17.5 11.6 17.9 16.9 10.8 16.5 47.3 16.5 11.4 27.2 13.9 15.2 35.8 151.2 24.4 22.8 14.0 15.0 8.3 18.8 44.2 14.9 26.6 16.5 14.9 19.5 16.1 20.0 16.0 41.5 33.9 12.4 14.8 14.2 15.0 12.1 15.5 14.1 27.0 38.2 47.1 34.5 24.5 24.7 15.8 177.3 37.4 37.2 50.5 37.1 54.7 88.2 140.8 105.4 103.8 114.5 114.0 172.6 86.3 34.2 57.7 51.3 151.1 44.1 150.1 167.0 59.1 51.3 55.6 59.8 122.8 41.7 87.6 22.5 51.1 95.5 77.4 191.7 79.0 91.2 38.7 41.8 28.4 78.8 101.7 102.5 129.0 9.9 80.0 276.3 100.6 63.7 69.4 117.1 92.7 29.5 33.8 63.6 239.7 49.5 34.7 159.7 69.3 82.8 34.3 67.0 93.2 123.0 40.5 48.3 98.1 65.0 127.6 22.1 2.3 34.2 4.1 12.9 65.5 29.9 103.7 28.2 24.1 83.1 155.0 21.3 19.2 11.1 20.7 80.4 57.6 55.7 36.3 13.0 18.7 13.5 17.7 13.9 15.2 14.0 15.0 16.5 14.2 14.1 15.8 9.8 83.3 75.8 136.5 84.2 94.2 73.5 102.0 105.9 16.3 26.2 26.0 67.8 38.6 72.4 31.3 56.3 136.7 25.9 11.0 92.0 83.2 80.7 40.6 18.8 14.9 10.8 27.7 245.3 67.5 139.5 27.0 23.0 55.6 21.5 9.7 17.2 130.1 39.3 11.8 287.7 12.1 44.7 25.2 50.0 26.9 16.8 33.7 48.0 198.6 44.1 14.1 11.3 140.8 165.4 62.7 10.4 12.0 39.1 92.1 5.0 64.5 33.5 25.0 6.6 20.4 26.0 17.4 14.3 96.7 97.0 107.3 32.7 17.0 20.5 66.3 ADORA3 AD026 ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 17.9;Kupffer cells: 79.2;Late spermatids: 18.2;Macrophages: 26.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 601.6" "Lineage enriched" "Detected in many" 40 "granulocytes: 601.6" "Cell line enriched" "Detected in some" 9 "HMC-1: 108.1" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" 4.5 15.0 8.9 4.3 9.2 0.2 5.5 10.6 14.6 4.4 8.8 6.6 4.5 1.9 0.2 2.5 3.6 5.8 3.4 8.8 12.3 1.6 3.3 3.5 6.4 16.1 11.1 1.8 1.8 3.1 2.6 2.8 14.9 2.4 5.1 1.0 2.8 2.4 0.5 0.9 9.4 4.8 13.5 4.3 3.0 1.2 16.9 3.5 1.4 1.0 2.7 4.3 1.7 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.0 0.0 0.0 0.0 108.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.0 8.1 601.6 0.0 5.6 0.1 0.2 0.0 0.0 15.0 0.1 0.1 0.1 2.0 0.1 2.1 3.0 0.0 2.5 8.9 9.2 10.6 14.6 8.8 12.3 16.1 11.1 14.9 13.5 16.9 21.8 0.2 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.0 7.3 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 1.8 0.2 17.9 0.0 0.0 0.0 0.0 79.2 4.4 18.2 0.3 26.3 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.1 0.4 0.0 1.6 0.0 0.0 0.1 AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.5;parathyroid gland: 68.7;thyroid gland: 82.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 40.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 122.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "A-431: 74.4;CAPAN-2: 77.4;EFO-21: 56.4;HaCaT: 98.7;RPMI-8226: 51.3;RPTEC TERT1: 59.7" "Low region specificity" "Detected in all" HPA037843 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" "HPA037843: AB_10669990" "unprognostic (2.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (5.06e-3)" "unprognostic (4.14e-2)" "unprognostic (9.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.11e-1)" "unprognostic (3.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.86e-1)" 7.6 2.4 15.7 4.2 12.9 0.1 10.2 21.5 13.1 21.8 5.9 13.0 3.9 23.9 13.2 9.3 22.9 4.5 4.7 11.8 12.4 17.6 1.7 5.3 4.3 12.9 12.8 15.1 11.9 68.7 2.4 18.4 13.6 13.1 5.1 3.7 6.9 23.9 3.0 9.8 6.4 18.9 13.6 64.5 5.9 1.4 13.3 13.5 82.2 4.4 7.6 5.9 14.7 13.5 74.4 10.8 10.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 77.4 0.1 56.4 0.6 1.1 98.7 0.2 27.2 0.2 1.5 0.1 0.0 0.7 0.0 3.0 0.0 2.7 0.0 28.9 8.1 7.1 0.3 0.3 2.8 0.0 0.2 0.0 3.1 1.9 0.1 0.5 2.0 0.5 0.9 0.8 51.3 59.7 0.6 0.3 0.5 2.3 1.7 2.9 16.0 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.6 1.1 1.2 0.0 1.6 0.3 0.9 0.1 0.4 0.0 0.1 1.8 0.6 15.7 12.9 21.5 13.1 11.8 12.4 12.9 12.8 13.6 13.6 13.3 13.5 14.6 0.0 0.0 0.7 1.2 12.4 7.3 3.1 5.2 0.8 1.8 5.3 2.2 0.0 1.8 40.5 0.0 1.5 2.4 8.1 0.0 0.6 1.0 5.3 7.4 14.5 0.0 0.8 6.5 14.3 1.2 10.7 3.1 9.5 0.0 0.3 13.2 0.0 0.5 1.7 10.1 1.8 0.0 0.0 3.7 3.0 3.1 0.5 5.4 34.7 0.6 3.2 0.0 122.6 0.6 23.2 1.7 1.9 0.1 3.7 2.2 0.4 1.5 0.6 19.7 21.4 24.7 0.0 0.8 2.3 6.8 0.3 3.4 2.4 2.2 4.3 AGA ASRG ENSG00000038002 Aspartylglucosaminidase P20933 4 177430774-177442437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 77.5;Karpas-707: 111.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031415, HPA031417" Enhanced "Intracellular and membrane" NA NA 36000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA031415: AB_10603578, HPA031417: AB_10670967" "unprognostic (8.76e-2)" "unprognostic (1.56e-1)" "unprognostic (2.22e-3)" "unprognostic (2.11e-3)" "unprognostic (2.70e-2)" "prognostic unfavorable (8.61e-4)" "prognostic unfavorable (1.99e-4)" "unprognostic (3.79e-1)" "unprognostic (6.44e-2)" "unprognostic (4.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.09e-1)" "unprognostic (7.49e-2)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (7.42e-2)" "unprognostic (1.47e-2)" 9.4 13.3 8.1 9.1 10.4 15.4 21.1 9.8 12.0 9.2 16.2 13.1 9.6 8.6 30.2 15.9 8.4 13.1 7.5 8.4 9.9 15.3 18.7 11.6 12.2 11.4 9.1 10.2 15.1 17.1 6.1 8.4 11.4 11.8 13.1 6.6 14.9 9.8 9.0 20.6 12.4 9.5 9.5 10.3 16.2 13.2 8.6 11.1 15.8 5.8 15.6 10.9 8.2 13.7 5.4 11.9 13.3 18.8 14.9 13.2 9.0 39.5 77.5 20.1 24.8 6.2 26.2 26.9 7.2 30.0 9.7 6.5 11.3 13.0 39.4 17.3 7.5 11.2 11.9 17.3 10.0 19.6 7.4 9.6 22.5 14.7 6.5 18.0 18.7 11.4 10.3 111.6 8.0 14.6 15.9 12.0 5.2 10.5 12.2 5.0 5.4 4.0 20.5 12.9 7.3 16.4 11.9 10.3 32.2 9.9 23.3 39.8 6.1 13.9 12.3 6.6 15.2 21.2 17.4 14.0 22.3 22.0 16.0 26.4 15.3 23.9 15.6 27.5 17.9 13.9 16.6 18.8 14.8 12.9 14.8 21.3 3.3 12.7 35.8 15.8 17.8 15.1 8.1 10.4 9.8 12.0 8.4 9.9 11.4 9.1 11.4 9.5 8.6 13.7 12.6 12.8 13.5 2.6 20.5 24.0 17.4 26.9 12.5 3.9 19.8 16.9 7.5 15.7 21.7 14.7 2.1 26.3 17.6 8.4 5.9 28.2 13.6 8.9 8.5 10.9 5.4 7.8 3.7 31.3 32.0 16.0 13.7 12.5 14.0 13.9 8.2 23.5 23.1 6.7 2.3 18.2 14.2 15.4 23.3 9.2 11.1 15.9 39.2 2.8 23.8 19.1 11.3 3.5 19.3 21.4 9.1 9.8 48.8 13.4 15.1 22.1 10.5 4.8 0.0 8.4 14.1 35.8 36.6 23.7 27.3 22.7 22.5 14.1 13.6 17.7 AHCYL1 "IRBIT, PPP1R78, XPVKONA" ENSG00000168710 "Adenosylhomocysteinase like 1" O43865 1 109984765-110023742 "Metabolic proteins, Predicted intracellular proteins, Transporters" "One-carbon metabolism" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 337.1" "Cell type enhanced" "Detected in all" "Astrocytes: 328.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042589 Approved Supported Cytosol NA NA 160000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA042589: AB_10793885" "unprognostic (8.72e-2)" "unprognostic (2.34e-1)" "prognostic favorable (7.00e-4)" "unprognostic (1.83e-3)" "unprognostic (5.01e-2)" "unprognostic (1.81e-1)" "unprognostic (2.72e-2)" "unprognostic (3.09e-2)" "unprognostic (1.32e-1)" "unprognostic (7.01e-2)" "unprognostic (2.46e-1)" "unprognostic (1.68e-1)" "unprognostic (2.38e-2)" "unprognostic (3.79e-2)" "unprognostic (2.89e-1)" "unprognostic (8.87e-2)" "unprognostic (4.84e-3)" 68.0 66.1 222.3 33.5 271.0 14.7 51.4 244.2 238.0 66.5 175.2 52.1 126.8 54.3 91.8 47.9 72.9 65.2 38.2 183.8 300.2 102.1 69.2 44.6 31.5 337.1 292.5 53.0 73.3 178.5 51.4 56.3 271.6 44.2 51.6 68.8 50.9 64.1 91.8 38.5 64.1 57.3 310.0 34.6 56.3 28.3 299.6 32.2 75.3 44.6 37.5 49.3 39.9 295.6 100.9 83.4 77.3 80.5 182.8 106.8 127.2 78.1 87.7 72.2 70.7 65.3 56.4 42.5 64.9 115.5 55.0 63.0 69.2 89.1 95.0 355.3 59.8 70.8 106.5 69.5 188.4 61.1 47.7 109.7 55.2 90.0 131.0 175.5 92.2 70.7 51.8 84.1 75.7 80.1 51.3 30.2 91.5 140.6 64.1 54.9 161.1 47.7 157.7 99.8 75.4 49.1 121.1 142.9 165.2 116.8 76.5 60.3 80.3 69.3 67.3 82.8 70.4 68.8 30.5 36.0 142.2 65.7 145.1 3.9 5.0 4.6 2.2 5.4 2.3 3.9 2.3 3.1 3.5 4.4 2.4 2.3 4.7 2.5 3.8 3.2 5.0 2.2 222.3 271.0 244.2 238.0 183.8 300.2 337.1 292.5 271.6 310.0 299.6 295.6 67.3 35.3 74.8 328.1 30.1 89.2 100.1 61.7 47.8 62.3 105.9 71.2 49.8 85.8 68.0 117.7 223.1 80.7 29.4 72.0 125.2 142.2 41.6 226.2 69.1 59.0 85.5 42.0 48.7 110.5 50.4 107.4 69.8 181.1 31.7 81.1 61.8 158.2 42.8 63.9 50.4 71.1 65.1 75.8 67.7 29.6 93.5 62.2 62.2 53.4 57.2 99.9 19.6 60.8 53.2 100.8 38.5 81.6 27.0 108.1 134.3 143.6 83.5 105.7 46.0 87.9 105.7 31.6 13.1 75.6 108.4 100.3 26.8 61.4 78.9 134.2 AIF1 "AIF-1, Em:AF129756.17, IBA1, IRT-1" ENSG00000204472 "Allograft inflammatory factor 1" P55008 6 31615217-31617021 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 235.0;lymphoid tissue: 346.6" "Group enriched" "Detected in many" 22 "Hofbauer cells: 1777.1;Kupffer cells: 2140.2;Langerhans cells: 1359.1;Macrophages: 1494.0;monocytes: 1022.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 26 "classical monocyte: 3823.3;intermediate monocyte: 6550.1;myeloid DC: 2043.3;neutrophil: 2943.0;non-classical monocyte: 7744.5" "Group enriched" "Detected in all" 74 "dendritic cells: 2043.3;granulocytes: 2943.0;monocytes: 7744.5" "Group enriched" "Detected in some" 4 "HEL: 204.6;HMC-1: 329.6;NB-4: 264.7;THP-1: 184.2;U-937: 114.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049234, HPA062949" Enhanced Uncertain Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "HPA049234: AB_2680685, HPA062949: AB_2732694" "unprognostic (3.20e-2)" "unprognostic (7.21e-3)" "unprognostic (6.11e-2)" "unprognostic (2.33e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (6.98e-2)" "unprognostic (4.83e-2)" "unprognostic (2.72e-2)" "unprognostic (7.56e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.29e-1)" "unprognostic (1.02e-2)" "unprognostic (9.59e-2)" "unprognostic (4.89e-2)" 79.6 46.6 24.9 182.3 25.5 235.0 47.2 26.6 33.0 29.3 32.2 48.3 36.4 17.1 12.1 18.7 19.7 61.3 21.1 25.0 31.3 74.3 81.2 99.3 116.8 45.1 36.4 14.4 12.4 12.9 17.3 109.5 36.8 22.3 57.2 3.9 20.3 24.0 6.1 11.7 44.5 74.7 34.3 346.6 22.2 8.7 32.1 69.1 13.8 16.6 57.1 95.3 13.5 42.7 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 204.6 0.0 0.0 0.0 30.0 329.6 0.0 0.0 0.0 0.0 0.0 0.0 51.6 0.9 0.2 0.0 0.0 2.3 264.7 0.4 0.0 0.0 35.9 0.4 8.9 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 184.2 0.1 0.0 0.2 0.1 0.3 0.2 0.0 1.3 0.2 114.6 0.0 33.1 3823.3 177.9 10.2 6550.1 12.7 57.5 10.8 9.3 2043.3 6.3 33.1 26.2 2943.0 14.5 7744.5 144.2 10.7 4449.8 24.9 25.5 26.6 33.0 25.0 31.3 45.1 36.4 36.8 34.3 32.1 42.7 12.0 25.6 59.6 0.0 39.2 32.5 0.7 0.0 0.6 0.1 5.3 24.3 7.5 18.6 19.2 42.3 0.0 11.1 31.2 1.0 0.0 0.3 1.9 0.6 0.7 28.7 1.2 65.0 0.0 0.4 15.4 20.6 0.5 0.4 68.3 0.4 35.3 13.4 1777.1 0.0 0.0 0.1 0.0 2140.2 1359.1 4.9 7.5 1494.0 39.2 10.3 1022.6 0.0 32.0 0.5 0.1 0.2 11.1 0.7 7.2 0.4 0.3 4.2 10.2 0.1 52.6 4.7 6.5 0.5 1.5 2.1 28.3 22.7 46.1 1.9 0.6 0.3 AIF1L "C9orf58, FLJ12783, IBA2" ENSG00000126878 "Allograft inflammatory factor 1 like" Q9BQI0 9 131096476-131123152 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 284.4;kidney: 313.2;lymphoid tissue: 206.8" "Group enriched" "Detected in many" 4 "Adipocytes: 122.9;Collecting duct cells: 356.8;Distal tubular cells: 289.5;Extravillous trophoblasts: 383.2;Proximal tubular cells: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 140.3;MCF7: 96.7;NTERA-2: 106.7;RPTEC TERT1: 299.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020522, HPA056852" Enhanced NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" "HPA020522: AB_2670463, HPA056852: AB_2683256" "unprognostic (2.59e-2)" "unprognostic (1.83e-3)" "unprognostic (2.55e-2)" "unprognostic (2.81e-2)" "unprognostic (1.78e-2)" "unprognostic (2.01e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.77e-1)" "unprognostic (4.39e-1)" "unprognostic (2.81e-2)" "unprognostic (2.68e-1)" "prognostic favorable (5.54e-6)" "unprognostic (2.48e-2)" "unprognostic (2.37e-1)" "unprognostic (1.38e-2)" "unprognostic (6.20e-2)" 44.7 4.8 165.6 4.7 199.6 2.3 39.9 179.6 284.4 20.2 101.5 7.2 1.3 13.5 9.3 105.8 10.8 8.3 41.8 145.4 160.9 313.2 1.6 12.2 1.9 209.2 204.2 5.1 6.5 80.6 18.2 23.8 196.2 6.6 5.7 6.9 32.1 36.6 14.6 15.9 7.9 10.0 172.9 206.8 9.0 6.5 188.0 3.9 91.9 21.9 5.8 9.2 35.3 225.1 0.5 2.2 140.3 24.1 0.0 0.0 59.5 0.0 0.3 0.1 0.3 26.8 11.3 0.0 63.5 0.0 3.0 13.5 21.2 1.5 0.8 0.3 30.0 15.7 7.4 51.4 0.3 0.1 7.6 1.2 6.6 0.5 0.7 0.4 6.7 39.3 10.6 0.1 0.0 96.7 9.3 1.9 106.7 9.0 10.1 0.2 1.9 39.6 299.9 8.5 54.3 8.7 7.4 60.0 20.4 82.7 57.6 0.9 0.9 3.8 10.2 0.5 30.8 0.4 0.5 0.4 6.1 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 165.6 199.6 179.6 284.4 145.4 160.9 209.2 204.2 196.2 172.9 188.0 225.1 122.9 0.0 0.0 5.9 2.8 4.1 2.1 1.5 1.2 0.1 45.0 29.5 6.6 0.0 3.5 356.8 0.0 4.5 1.3 0.8 289.5 1.5 1.0 4.1 3.5 35.0 3.6 0.0 0.3 0.8 383.2 15.5 0.5 15.0 0.0 10.1 33.5 0.0 7.0 0.0 0.3 2.1 2.0 0.3 2.0 3.5 37.6 2.3 67.6 21.5 0.0 15.1 0.0 8.0 36.3 2.9 0.3 59.0 0.0 7.7 0.0 201.5 0.6 0.2 0.0 3.3 10.3 0.2 5.3 4.4 2.4 21.1 1.7 29.9 1.3 2.0 AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 235.8" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 245.4;Proximal tubular cells: 261.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060766 Approved Approved "Golgi apparatus" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "HPA060766: AB_2684356" "unprognostic (2.70e-2)" "prognostic unfavorable (3.26e-6)" "unprognostic (4.27e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (5.34e-2)" "prognostic unfavorable (3.25e-7)" "unprognostic (1.91e-2)" "unprognostic (8.75e-3)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.74e-2)" "unprognostic (3.07e-2)" "unprognostic (1.43e-1)" "unprognostic (9.11e-2)" "unprognostic (2.75e-1)" 42.0 29.8 43.7 10.4 44.6 31.6 30.0 43.3 46.1 17.6 48.2 23.0 46.6 14.4 33.0 34.1 34.4 24.5 54.1 44.1 49.1 102.0 235.8 19.9 10.7 45.0 43.4 34.7 31.0 31.0 36.6 11.9 46.4 22.7 18.8 33.9 19.8 24.1 23.7 16.8 45.9 15.2 47.1 20.1 20.8 15.7 51.0 6.8 42.9 32.5 14.8 29.4 26.1 52.5 32.6 25.2 20.6 56.9 29.7 22.3 7.6 28.3 57.1 26.8 61.9 37.5 81.5 20.0 40.5 66.1 41.7 42.0 26.5 79.2 64.2 67.2 63.0 5.6 35.6 157.3 40.8 46.0 2.7 32.9 76.7 35.7 129.6 88.2 10.9 30.8 4.0 67.6 59.3 45.6 14.2 9.8 40.8 37.4 27.6 20.2 61.6 36.6 100.6 77.6 75.5 42.4 35.5 33.2 17.2 36.0 31.7 96.0 3.0 25.2 27.8 22.7 33.4 99.6 95.1 2.1 59.7 9.5 26.9 12.0 6.2 9.6 6.6 29.3 15.1 9.6 12.4 10.6 33.0 5.6 13.1 10.0 11.3 11.8 35.4 2.9 9.7 9.2 43.7 44.6 43.3 46.1 44.1 49.1 45.0 43.4 46.4 47.1 51.0 52.5 40.8 16.0 27.7 114.9 22.0 25.0 51.8 82.5 27.9 68.3 69.9 65.4 73.7 72.9 66.9 51.5 25.0 79.6 8.6 12.6 52.8 60.3 22.4 99.8 25.9 32.8 39.5 29.3 204.3 31.5 10.5 42.2 26.0 83.1 36.8 90.9 36.8 229.6 32.7 53.8 245.4 33.3 59.0 40.1 42.3 7.0 32.0 37.2 55.2 100.2 18.2 74.3 8.2 105.1 172.9 25.8 65.2 38.4 47.7 35.3 232.9 261.5 69.1 36.9 32.9 41.7 50.8 5.6 17.3 53.1 45.7 108.1 18.5 61.5 42.4 53.2 AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 185.9;Late spermatids: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome,Cytosol" No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" "Centrosome, Cytosol" "CAB005361: AB_2302969, HPA070217: " "unprognostic (5.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (8.58e-2)" "unprognostic (8.73e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (9.54e-4)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (2.25e-2)" "unprognostic (1.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (2.55e-2)" 46.0 58.0 18.7 12.5 19.6 11.6 40.0 20.6 27.1 26.1 19.8 40.8 15.2 32.4 21.6 29.7 29.6 7.7 48.4 19.8 20.3 54.9 46.6 29.5 13.0 19.7 20.1 32.6 35.8 11.6 28.6 12.1 19.5 32.9 12.6 23.2 30.9 8.3 79.8 20.6 30.1 9.5 18.7 28.0 36.4 43.3 19.5 13.3 33.0 23.3 12.5 35.5 28.0 20.7 40.3 18.8 28.0 42.6 43.6 26.3 51.1 59.3 18.6 23.8 30.7 56.0 35.5 82.1 54.9 23.4 62.2 14.0 37.2 23.3 40.0 33.1 15.7 40.7 47.8 44.9 33.0 49.5 17.1 14.0 33.3 23.0 37.0 25.0 14.8 45.8 36.6 29.3 28.6 42.1 50.2 31.4 25.0 17.9 10.5 55.8 34.5 44.5 40.3 31.3 14.4 13.3 28.2 26.4 44.6 21.3 25.1 54.7 29.5 20.4 34.6 41.4 47.6 33.1 74.4 75.3 29.8 69.3 28.9 25.2 16.8 20.1 19.2 22.1 20.3 29.8 22.8 24.9 24.8 26.1 24.5 26.3 2.7 24.1 21.0 29.9 25.8 13.3 18.7 19.6 20.6 27.1 19.8 20.3 19.7 20.1 19.5 18.7 19.5 20.7 51.5 22.4 30.0 14.0 33.9 0.0 95.7 0.0 33.6 19.8 57.3 86.6 55.6 18.6 16.7 23.9 10.4 86.7 27.2 16.8 185.9 75.6 174.9 36.4 34.6 38.6 9.7 29.2 14.8 78.5 95.1 47.3 16.8 30.2 21.5 31.7 30.7 42.5 71.3 20.2 15.4 21.3 0.0 30.6 0.0 275.9 33.5 32.2 0.0 6.5 42.4 58.7 34.0 13.0 17.0 59.1 25.5 32.0 29.4 116.6 48.6 149.8 18.2 29.3 52.6 40.9 50.0 56.5 37.9 24.3 0.0 66.2 27.6 44.7 32.9 88.1 AK7 "CFAP75, FAP75, FLJ32864" ENSG00000140057 "Adenylate kinase 7" Q96M32 14 96392128-96489427 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.3" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 97.9;Respiratory ciliated cells: 137.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 9.0" "Lineage enriched" "Detected in single" 29 "granulocytes: 9.0" "Cell line enhanced" "Detected in many" "BEWO: 17.0;CAPAN-2: 15.1;MCF7: 49.5;REH: 35.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003543 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA003543: AB_1078117" "unprognostic (4.18e-3)" "unprognostic (1.14e-1)" "unprognostic (9.40e-3)" "prognostic favorable (3.18e-4)" "unprognostic (4.98e-5)" "unprognostic (8.41e-2)" "unprognostic (9.81e-3)" "unprognostic (1.29e-1)" "unprognostic (9.02e-2)" "unprognostic (3.65e-4)" "unprognostic (8.64e-2)" "unprognostic (1.89e-1)" "prognostic favorable (1.14e-4)" "unprognostic (2.00e-2)" "unprognostic (1.23e-2)" "unprognostic (4.01e-2)" "unprognostic (2.25e-3)" 0.7 2.6 2.0 0.6 3.1 1.5 1.4 1.1 1.7 1.7 13.2 2.1 1.9 2.1 3.9 1.5 24.3 2.6 0.7 2.2 5.2 4.5 1.6 4.2 0.6 6.9 9.4 0.4 2.2 6.9 5.1 0.5 5.6 0.9 1.6 3.0 1.0 1.3 0.3 6.1 1.2 1.1 4.4 3.3 2.8 7.6 5.0 0.5 2.7 0.0 0.4 0.5 1.0 4.2 0.2 4.9 2.0 1.5 0.8 2.6 17.0 0.3 0.6 0.3 0.3 0.5 15.1 0.4 0.3 0.0 0.3 1.9 4.7 0.2 0.1 2.2 0.4 0.4 2.4 0.2 0.8 0.1 0.3 0.2 0.6 2.5 0.1 0.8 0.2 1.4 0.2 0.3 0.3 49.5 0.3 0.3 0.8 2.2 1.0 35.2 0.3 0.4 7.6 0.3 3.1 6.7 1.9 0.6 0.1 1.8 4.2 0.2 0.1 0.4 0.2 0.6 0.2 0.6 2.3 0.2 0.2 0.0 0.7 9.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.1 2.0 3.1 1.1 1.7 2.2 5.2 6.9 9.4 5.6 4.4 5.0 4.2 1.6 6.4 4.1 0.7 0.8 1.8 0.9 3.6 1.8 0.2 0.9 0.3 0.4 4.3 12.3 7.3 2.1 0.7 0.1 1.4 3.9 3.2 18.7 97.9 1.7 1.9 1.2 6.9 2.0 1.1 1.7 0.8 5.1 11.6 0.0 0.1 0.7 2.4 0.2 0.0 2.4 0.3 4.1 0.3 0.4 4.1 0.0 0.5 1.8 0.0 0.0 0.6 0.0 0.5 3.7 0.5 0.1 0.0 0.0 0.5 1.0 3.4 137.1 1.8 0.0 0.4 1.6 25.4 9.1 0.7 3.0 2.9 0.2 1.5 1.2 0.6 ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698863 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 311.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" NA NA 2000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA006077: , HPA010873: AB_1078126" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (4.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.21e-2)" "unprognostic (1.25e-1)" "unprognostic (4.14e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (1.83e-1)" "prognostic favorable (4.56e-4)" "unprognostic (5.51e-2)" "unprognostic (9.05e-2)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (1.43e-1)" "unprognostic (2.15e-1)" 119.2 105.5 49.6 29.8 51.0 24.8 76.8 49.3 60.3 51.5 62.5 45.7 54.8 38.6 93.4 105.6 50.2 32.0 48.2 47.4 57.5 142.4 206.5 38.5 40.3 50.5 52.1 53.6 44.0 81.9 39.9 38.0 51.4 65.3 50.6 46.4 104.1 45.6 93.6 54.7 48.6 42.0 50.7 37.9 39.5 63.4 49.3 39.0 123.0 56.4 60.1 39.4 43.9 55.6 55.7 53.5 48.7 44.1 152.1 132.8 40.7 71.9 101.5 70.8 61.0 33.4 40.7 0.1 67.1 64.8 34.9 42.8 40.0 70.3 83.0 25.9 50.6 35.3 34.7 36.5 78.2 56.0 36.1 86.0 34.8 75.2 62.5 97.8 62.2 45.9 56.9 48.4 111.7 33.4 37.6 57.6 71.3 145.1 64.7 31.7 62.0 74.3 92.5 52.0 57.7 39.8 51.4 57.1 67.4 65.6 108.8 84.0 61.9 42.5 41.5 52.4 37.1 44.7 62.5 54.8 47.9 52.6 41.7 61.8 35.2 50.9 45.5 37.7 48.8 49.9 43.8 49.6 34.5 46.8 43.8 50.4 51.3 43.0 45.3 21.6 69.8 45.6 49.6 51.0 49.3 60.3 47.4 57.5 50.5 52.1 51.4 50.7 49.3 55.6 56.2 16.0 47.6 12.7 43.3 32.6 43.3 43.8 68.3 25.0 83.0 54.6 46.5 55.8 36.8 51.5 22.9 48.5 39.3 43.9 97.8 42.9 45.4 27.7 39.1 49.4 55.8 28.2 5.6 37.0 76.4 60.6 36.2 20.4 38.0 60.9 59.3 158.8 61.9 13.5 8.3 56.9 32.6 59.1 24.9 39.8 95.4 43.8 56.9 6.5 34.6 311.5 39.1 12.1 12.2 32.2 33.1 115.5 34.8 39.6 80.3 204.4 59.4 28.9 26.3 32.5 40.1 85.6 49.9 123.8 51.9 38.2 43.7 148.4 63.6 28.3 ALG8 MGC2840 ENSG00000159063 "ALG8 alpha-1,3-glucosyltransferase" Q9BVK2 11 78095244-78139660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 105.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051898 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA051898: AB_2681656" "unprognostic (1.37e-1)" "unprognostic (9.24e-2)" "unprognostic (4.60e-2)" "unprognostic (2.69e-2)" "unprognostic (2.65e-1)" "unprognostic (6.49e-2)" "unprognostic (5.38e-3)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-3)" "unprognostic (5.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.35e-2)" "unprognostic (1.19e-1)" "unprognostic (2.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.37e-2)" 22.8 33.0 12.7 13.4 14.3 9.2 25.6 13.9 16.4 18.7 15.4 17.5 13.3 15.9 33.2 19.0 18.8 12.0 17.9 12.9 13.3 24.9 47.1 15.0 14.6 14.1 13.1 22.1 23.8 23.7 19.8 18.7 13.8 19.1 21.8 10.4 21.7 18.0 12.1 16.6 15.5 16.4 13.5 18.3 20.2 43.5 13.1 17.8 22.4 8.9 19.8 18.4 16.0 15.2 27.8 74.4 62.8 56.6 63.7 42.5 37.6 38.6 57.8 68.6 67.4 127.9 102.0 61.4 74.5 51.5 92.3 86.5 87.0 56.5 111.9 46.3 50.8 74.3 56.5 62.2 38.9 71.8 39.6 34.4 36.4 81.8 37.9 37.5 50.3 58.0 98.2 65.8 97.7 38.6 53.3 61.9 81.9 200.5 38.1 63.6 32.6 168.3 70.0 40.4 20.2 44.8 62.0 102.2 29.4 65.6 106.5 50.8 32.0 43.5 50.6 102.5 35.1 46.6 88.0 80.3 26.7 71.4 84.4 1.2 30.0 5.4 25.1 34.5 29.1 37.2 25.5 25.7 34.2 31.3 29.7 26.2 2.6 29.1 39.9 33.1 22.5 27.6 12.7 14.3 13.9 16.4 12.9 13.3 14.1 13.1 13.8 13.5 13.1 15.2 11.9 12.8 11.6 12.4 21.0 10.5 23.3 49.6 26.2 14.7 18.3 16.3 6.9 20.0 35.2 20.2 18.8 53.8 9.1 7.0 5.9 24.4 18.9 11.0 16.9 17.2 7.8 9.9 21.3 25.4 59.5 19.4 11.7 13.8 11.4 36.4 9.3 40.2 31.4 16.8 18.0 15.9 32.6 17.0 10.8 14.0 18.0 15.3 26.6 12.2 12.3 8.2 21.6 13.0 20.7 17.7 6.4 15.8 43.1 16.9 7.7 15.8 21.7 13.5 0.0 14.2 19.6 105.0 37.8 20.9 8.9 32.7 15.2 16.9 16.8 15.2 ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;thyroid gland: 2.4" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 5.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted - unknown location" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.2 0.0 1.1 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.7 0.2 0.0 0.4 0.1 0.1 0.0 2.4 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.5 0.1 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALKBH4 FLJ20013 ENSG00000160993 "AlkB homolog 4, lysine demethylase" Q9NXW9 7 102456238-102464863 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Actin-binding, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051422 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA051422: AB_2681480" "unprognostic (1.18e-2)" "unprognostic (7.35e-2)" "unprognostic (3.50e-2)" "unprognostic (1.75e-2)" "unprognostic (4.14e-3)" "unprognostic (3.83e-2)" "unprognostic (2.71e-3)" "unprognostic (6.04e-3)" "unprognostic (1.34e-1)" "unprognostic (7.25e-3)" "unprognostic (3.20e-3)" "unprognostic (1.10e-1)" "prognostic favorable (3.09e-4)" "unprognostic (1.44e-2)" "unprognostic (2.04e-1)" "unprognostic (2.23e-1)" "unprognostic (5.44e-2)" 3.4 5.2 8.3 2.9 9.0 5.0 3.6 10.0 9.4 4.3 7.6 3.9 3.9 4.6 3.5 4.2 3.8 2.3 4.2 8.7 8.8 5.0 4.9 2.7 4.3 8.5 8.5 4.0 5.0 6.9 5.1 2.9 8.8 4.1 2.6 2.3 5.0 3.2 4.3 4.9 5.0 2.9 8.6 7.1 4.3 2.7 8.9 4.4 5.8 4.3 3.3 3.7 3.8 9.2 5.4 7.2 5.9 13.9 4.0 4.5 6.5 4.0 6.9 8.4 7.9 8.2 7.1 6.3 6.6 5.7 7.4 4.3 7.6 5.6 6.2 6.3 15.9 6.3 3.3 6.0 6.2 5.6 5.9 6.8 7.6 6.5 2.9 7.2 5.5 10.1 11.2 7.5 5.2 19.6 15.7 17.5 9.0 10.2 10.9 9.3 6.2 11.2 7.0 5.8 7.3 10.9 5.0 15.1 5.6 7.4 6.3 6.6 1.8 8.9 10.2 13.8 8.8 10.2 8.4 11.7 5.2 7.6 9.4 3.7 5.4 3.0 6.1 4.8 6.4 5.2 4.7 8.0 5.4 4.6 4.7 6.1 1.6 9.2 9.8 6.9 4.9 3.4 8.3 9.0 10.0 9.4 8.7 8.8 8.5 8.5 8.8 8.6 8.9 9.2 10.2 6.4 5.8 2.3 7.0 8.3 4.3 12.9 5.2 16.6 8.1 11.7 2.2 11.5 5.9 9.2 4.2 25.6 9.2 7.3 25.4 16.3 1.3 6.8 12.2 10.5 6.1 19.6 5.2 14.9 15.4 10.8 7.7 10.0 3.8 11.7 10.4 9.1 15.3 28.6 6.2 8.1 10.2 12.0 5.8 1.9 14.0 7.2 3.6 2.8 14.6 13.4 25.7 2.0 4.5 11.8 10.6 21.4 8.3 6.3 12.0 18.8 4.6 10.2 0.0 7.6 9.5 11.9 16.9 9.5 7.4 11.1 8.7 17.7 10.1 1.8 ALOX5AP FLAP ENSG00000132965 "Arachidonate 5-lipoxygenase activating protein" P20292 13 30713478-30764426 "Disease related genes, Predicted membrane proteins" "Leukotriene biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 487.2;lung: 183.3;lymphoid tissue: 138.5" "Cell type enhanced" "Detected in many" "dendritic cells: 691.3;granulocytes: 609.1;Hofbauer cells: 492.2;Langerhans cells: 335.4;Macrophages: 637.0;NK-cells: 280.2;T-cells: 368.6" "Cancer enhanced" "Detected in all" "glioma: 49.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 9703.9;eosinophil: 4033.4;neutrophil: 4968.7;plasmacytoid DC: 3555.3" "Group enriched" "Detected in all" 8 "dendritic cells: 3555.3;granulocytes: 9703.9" "Cell line enhanced" "Detected in many" "HDLM-2: 658.4;HL-60: 352.3;HMC-1: 1072.9;THP-1: 434.2;U-937: 321.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026592 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA026592: AB_10601115" "unprognostic (1.17e-2)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (4.64e-3)" "unprognostic (7.18e-2)" "unprognostic (7.10e-2)" "unprognostic (7.79e-2)" "unprognostic (1.04e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (7.83e-2)" "unprognostic (6.63e-2)" "prognostic unfavorable (5.68e-4)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (2.59e-1)" 51.6 36.1 10.8 100.6 11.6 487.2 25.7 12.5 18.1 18.8 13.4 22.8 21.6 17.4 7.1 21.8 24.5 40.0 12.4 10.2 15.7 13.3 19.7 183.3 77.2 21.0 15.6 10.6 14.1 9.6 6.1 37.2 21.1 13.2 21.4 3.7 19.9 15.5 3.8 7.4 28.3 42.6 16.6 138.5 20.0 4.3 17.7 93.2 9.1 24.7 108.2 65.6 11.9 31.3 0.6 0.8 1.2 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 1.3 7.1 156.3 2.2 0.0 5.2 1.2 0.0 4.6 0.1 658.4 0.0 18.7 0.3 1.0 0.7 352.3 1072.9 0.8 0.2 0.1 37.9 8.1 1.4 33.3 0.1 3.2 1.9 0.1 19.8 12.7 0.0 0.0 0.2 3.2 3.9 12.4 1.4 0.3 10.2 0.1 0.2 0.3 0.9 2.3 0.0 434.2 1.1 0.0 3.2 0.3 2.6 66.2 0.5 103.8 1.0 321.1 1.4 9703.9 322.4 4033.4 546.0 17.2 808.3 477.9 536.4 449.0 198.5 489.2 271.6 260.7 4968.7 98.0 12.4 3555.3 843.9 775.2 10.8 11.6 12.5 18.1 10.2 15.7 21.0 15.6 21.1 16.6 17.7 31.3 3.5 41.7 102.0 0.0 117.6 23.7 2.6 1.8 1.2 0.0 3.3 9.1 4.1 10.0 23.7 0.0 0.0 3.1 691.3 4.0 15.6 2.3 5.6 14.3 0.7 17.2 26.4 27.1 0.4 1.0 4.0 11.2 21.4 0.7 609.1 1.9 7.1 1.8 492.2 0.0 0.4 2.0 4.1 144.3 335.4 4.5 4.7 637.0 42.7 13.1 217.1 0.1 280.2 0.5 0.3 6.4 3.1 4.1 31.1 1.5 7.3 2.0 11.1 0.1 32.9 4.4 4.0 0.4 1.1 1.7 24.7 4.9 368.6 0.0 2.0 1.4 AMIGO1 "AMIGO, KIAA1163" ENSG00000181754 "Adhesion molecule with Ig like domain 1" Q86WK6 1 109504178-109509738 "Predicted membrane proteins, Transporters" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 33.6;Excitatory neurons: 9.6;Inhibitory neurons: 15.9;Rod photoreceptor cells: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046152 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear bodies" "HPA046152: AB_2679559" "unprognostic (1.35e-1)" "unprognostic (3.94e-1)" "unprognostic (2.32e-2)" "unprognostic (4.78e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.16e-3)" "unprognostic (3.11e-1)" "unprognostic (9.06e-3)" "unprognostic (1.82e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.97e-1)" 3.8 10.7 12.7 2.7 13.8 0.4 3.2 11.7 20.0 3.6 8.2 6.9 2.1 4.3 11.7 2.8 3.3 2.8 8.6 14.3 12.6 5.2 2.8 4.6 4.1 11.5 10.7 8.8 6.8 12.4 7.4 1.9 12.5 6.3 2.4 23.4 7.6 7.7 19.3 2.4 3.8 4.5 7.9 3.3 4.6 2.9 12.6 2.7 6.5 11.9 3.3 3.9 2.8 11.8 2.3 1.1 2.4 8.3 3.0 1.3 2.9 3.6 2.0 4.4 2.1 0.5 0.1 0.1 1.0 2.5 1.0 1.2 6.5 0.2 3.7 0.9 0.5 0.0 1.6 0.7 2.5 1.9 4.6 0.6 2.8 1.5 0.0 0.4 1.1 1.3 1.9 0.0 0.1 4.1 0.4 3.9 1.3 2.0 2.5 0.6 0.0 0.3 5.1 1.1 8.1 2.7 0.9 11.0 3.2 1.0 3.2 2.8 1.0 0.1 4.8 3.0 1.5 0.2 0.0 0.0 1.6 0.0 2.4 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.9 1.1 0.0 0.0 2.3 1.7 0.0 0.9 0.0 0.0 0.7 0.4 12.7 13.8 11.7 20.0 14.3 12.6 11.5 10.7 12.5 7.9 12.6 11.8 0.6 3.2 2.0 5.9 0.2 0.6 0.4 0.3 0.6 33.6 2.4 1.4 8.9 1.5 0.3 3.7 4.2 1.3 0.6 1.5 0.0 1.2 0.0 0.4 0.4 1.6 4.8 0.0 9.6 0.9 0.2 1.9 0.0 0.7 0.0 1.4 1.1 1.0 0.2 5.0 15.9 1.0 2.0 0.6 0.0 0.1 2.1 0.2 0.0 2.8 0.8 6.7 0.0 3.0 2.1 0.8 1.6 5.7 0.1 1.1 2.3 0.8 0.1 9.4 0.0 4.3 1.5 1.2 1.4 0.2 0.4 0.3 1.8 0.9 1.5 0.3 ANAPC13 "APC13, DKFZP566D193, SWM1" ENSG00000129055 "Anaphase promoting complex subunit 13" Q9BS18 3 134477706-134486716 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 463.7;Proximal tubular cells: 373.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046114 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Mitochondria, Cytosol" "HPA046114: AB_10961429" "unprognostic (2.84e-2)" "prognostic favorable (1.66e-4)" "unprognostic (2.98e-1)" "unprognostic (7.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (3.57e-1)" "unprognostic (2.90e-1)" "unprognostic (2.28e-3)" "unprognostic (6.44e-2)" "unprognostic (4.36e-1)" "prognostic favorable (2.66e-7)" "unprognostic (3.10e-1)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-1)" 56.7 73.3 54.1 29.0 56.1 30.0 65.9 58.0 68.6 49.1 74.4 44.6 35.2 46.8 114.4 35.1 48.2 48.0 98.5 56.8 63.4 121.2 86.8 45.4 38.8 60.3 58.6 52.2 50.1 77.2 63.7 51.1 62.3 60.0 45.8 62.6 53.7 54.4 87.1 38.1 33.8 48.1 58.0 40.1 54.3 29.3 57.2 35.7 95.6 67.9 36.6 51.3 33.3 58.3 91.9 56.2 87.4 74.9 144.7 191.6 67.5 116.0 106.4 83.4 77.9 70.6 52.9 61.9 244.8 172.2 100.1 53.0 82.6 83.6 119.9 31.7 37.7 63.3 43.2 119.3 104.6 104.2 43.5 127.7 90.3 83.5 155.1 93.4 130.9 59.3 85.9 51.2 266.9 117.3 53.5 103.1 59.8 157.7 54.5 42.6 68.5 113.7 165.3 56.0 35.4 58.0 103.2 37.8 107.4 92.8 94.2 101.6 91.9 115.2 47.0 164.1 52.2 56.2 65.6 127.3 71.4 57.4 100.9 112.9 96.6 86.5 52.7 108.2 69.7 86.1 78.7 69.9 91.8 68.9 94.2 80.7 236.4 67.6 111.4 70.1 72.9 84.8 54.1 56.1 58.0 68.6 56.8 63.4 60.3 58.6 62.3 58.0 57.2 58.3 46.6 35.3 47.0 3.6 41.7 42.1 47.6 72.2 47.8 41.0 60.8 49.9 112.8 67.2 41.7 84.6 12.5 95.8 26.8 22.1 463.7 51.5 42.5 38.1 39.5 51.8 40.8 26.3 7.0 53.8 96.6 57.2 38.2 28.9 18.9 34.5 53.6 64.5 78.7 20.2 8.3 40.6 77.3 71.3 48.8 104.6 50.7 43.8 97.8 6.5 33.4 85.0 42.2 4.0 6.3 39.5 42.6 44.0 46.0 74.7 54.6 373.4 49.3 38.3 19.7 26.6 58.5 46.2 64.2 44.3 50.6 70.3 35.4 59.5 35.4 52.9 ANAPC15 "APC15, C11orf51, DKFZP564M082, HSPC020" ENSG00000110200 "Anaphase promoting complex subunit 15" P60006 11 72106378-72112780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036596 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA036596: AB_10671961" "unprognostic (1.17e-1)" "unprognostic (5.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.05e-2)" "unprognostic (1.86e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (9.18e-2)" "unprognostic (3.35e-2)" "prognostic favorable (2.55e-4)" "unprognostic (9.34e-3)" "unprognostic (1.76e-1)" "unprognostic (1.26e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (9.08e-2)" 28.9 44.2 47.0 30.0 47.5 95.9 30.0 47.8 61.1 24.3 45.8 67.1 30.7 43.4 38.3 53.2 30.4 18.3 62.2 47.2 47.7 48.8 44.0 30.0 43.5 46.4 46.8 22.4 39.2 25.4 32.8 19.2 47.2 52.0 40.6 42.8 39.9 38.8 95.2 39.6 40.1 31.9 46.4 41.2 46.5 72.0 46.3 72.6 44.7 64.3 44.3 41.6 29.5 49.0 74.0 109.4 87.5 55.8 25.5 41.2 41.4 77.1 70.1 121.3 80.2 128.8 78.4 98.8 72.9 110.3 59.0 122.6 133.4 144.0 113.9 64.0 63.3 113.1 124.9 84.5 30.2 110.8 101.3 43.2 56.2 68.9 91.6 45.4 80.7 136.7 83.3 66.6 80.0 127.2 214.5 102.9 70.9 155.3 62.3 89.6 217.4 67.2 106.1 50.5 61.9 53.8 79.0 76.5 127.0 46.8 89.6 58.6 73.4 55.5 72.9 110.5 82.8 68.0 71.5 125.3 34.0 87.8 31.7 29.7 168.5 136.3 73.3 114.2 78.0 94.5 93.4 86.3 148.8 71.4 110.9 101.5 68.4 72.4 107.4 119.1 153.0 124.1 47.0 47.5 47.8 61.1 47.2 47.7 46.4 46.8 47.2 46.4 46.3 49.0 20.1 16.0 16.5 2.9 36.1 41.8 71.2 83.5 44.3 32.9 43.2 55.6 3.9 12.8 50.6 23.9 27.1 84.7 40.5 82.9 123.3 49.4 15.4 38.8 21.3 22.8 49.6 34.1 7.1 102.7 78.8 18.3 36.7 27.8 30.4 27.2 15.0 44.1 82.8 13.5 7.3 66.2 61.1 48.5 47.5 13.4 6.8 48.0 26.6 1.0 58.8 44.1 36.0 5.5 5.2 53.1 61.4 23.0 47.1 43.8 56.2 123.6 45.6 43.3 19.7 16.0 35.3 115.9 139.9 53.8 41.1 46.7 41.1 32.3 71.5 61.7 ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 490.2;Excitatory neurons: 859.2;Inhibitory neurons: 881.3;Oligodendrocyte precursor cells: 592.6;Oligodendrocytes: 1579.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 50.3;SK-BR-3: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" 6.3 6.7 45.5 6.5 86.5 2.1 21.5 144.9 82.3 12.0 0.0 26.0 39.3 23.0 125.2 16.9 19.1 21.5 81.1 60.8 86.1 95.4 16.6 24.6 6.1 82.7 61.3 11.6 11.2 131.8 14.5 15.6 97.0 20.0 20.9 123.2 42.6 40.5 80.5 39.9 27.2 13.2 21.2 10.8 15.5 8.0 87.3 9.1 41.6 94.1 7.4 10.8 14.1 114.4 8.7 4.9 30.3 0.4 0.0 1.8 23.3 0.6 0.4 0.1 0.6 22.2 16.6 0.5 9.8 0.6 0.9 12.1 16.4 14.9 0.5 0.5 11.0 0.2 9.7 0.1 6.2 0.1 0.4 14.6 9.3 7.8 0.4 26.1 3.6 0.0 4.3 20.6 6.9 29.0 0.2 1.0 13.8 23.3 26.6 0.1 21.7 4.3 5.4 50.3 15.6 2.8 0.6 49.4 0.0 33.6 28.7 0.1 10.0 0.9 2.9 13.3 1.5 0.9 0.2 0.2 5.5 0.2 18.9 1.6 0.2 0.5 2.7 0.2 2.4 4.1 4.6 1.5 0.1 1.1 5.0 1.2 0.7 1.5 0.3 2.5 0.8 1.0 45.5 86.5 144.9 82.3 60.8 86.1 82.7 61.3 97.0 21.2 87.3 114.4 0.9 44.8 174.3 20.2 14.5 19.1 21.9 17.8 38.7 490.2 26.8 20.6 189.3 12.8 42.5 53.3 225.2 38.8 3.4 62.9 19.6 10.6 28.3 139.8 26.2 3.9 30.6 0.0 859.2 8.6 9.9 13.2 15.8 153.3 12.6 66.9 7.9 0.5 4.7 43.7 881.3 12.1 14.2 4.8 1.4 11.5 28.0 3.3 8.8 23.4 4.4 41.4 0.0 592.6 1579.5 4.8 41.8 5.7 3.4 12.2 62.5 51.3 66.7 216.6 0.0 30.2 11.7 1.1 2.3 35.9 18.2 25.0 18.5 4.5 17.8 18.4 ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 266.0" "Group enriched" "Detected in many" 5 "Early spermatids: 156.4;Oligodendrocytes: 441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "HBF TERT88: 655.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Midbody "CAB033902: AB_2058302, CAB062547: AB_2665622, CAB068175: AB_2665623, HPA005680: AB_2667388, HPA050556: AB_2681175" "unprognostic (4.23e-2)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.67e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (5.97e-7)" "prognostic unfavorable (6.99e-5)" "unprognostic (2.69e-2)" "unprognostic (3.66e-2)" "prognostic unfavorable (2.00e-6)" "unprognostic (3.13e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.29e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (4.04e-3)" 1.2 0.7 59.8 5.2 134.5 36.4 2.0 125.1 72.7 1.8 18.4 6.0 4.4 1.8 0.2 10.4 0.9 2.1 0.8 59.3 83.6 0.4 1.2 1.4 6.7 162.3 106.5 0.9 0.6 0.2 0.2 8.9 160.2 0.9 8.0 0.3 1.7 0.4 0.3 13.6 4.3 14.9 99.2 1.2 4.8 12.4 102.3 16.0 0.8 0.3 9.5 3.2 3.2 266.0 476.1 96.5 79.3 61.0 10.7 26.9 85.6 292.5 169.3 344.4 256.0 66.4 142.7 23.9 82.1 148.6 182.8 237.0 63.4 170.7 655.4 16.1 46.0 32.7 104.8 55.8 1.7 47.3 36.7 6.0 7.7 225.3 147.2 40.8 109.3 31.2 69.6 48.8 284.4 71.0 40.0 54.8 88.5 71.9 102.3 29.1 238.2 15.9 76.5 76.5 33.5 39.5 154.1 175.8 26.1 109.6 119.0 53.6 104.5 214.2 239.0 127.6 346.6 20.1 34.2 43.2 72.9 74.9 460.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.3 59.8 134.5 125.1 72.7 59.3 83.6 162.3 106.5 160.2 99.2 102.3 266.0 0.4 0.0 1.1 2.3 1.0 14.1 1.9 8.3 7.4 0.0 1.9 2.0 0.6 0.0 3.2 0.0 0.0 13.8 1.1 2.8 0.0 0.7 156.4 18.9 3.2 1.9 0.0 35.3 3.4 0.2 23.2 6.9 10.2 12.8 0.0 15.4 1.1 0.5 9.8 0.0 5.7 3.4 6.1 1.6 5.9 53.3 1.2 2.7 0.0 0.0 0.0 0.0 0.0 1.5 441.3 0.6 0.1 0.0 8.8 1.6 0.8 0.3 10.4 0.0 0.0 0.4 5.2 20.0 17.7 27.1 9.2 2.9 2.6 1.7 6.0 3.3 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANOS1 "ADMLX, KAL, KAL1, KALIG-1, WFDC19" ENSG00000011201 "Anosmin 1" P23352 X 8528874-8732137 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cell adhesion, Chemotaxis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.1" "Cell type enriched" "Detected in many" 11 "Alveolar cells type 1: 240.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 40.4;NTERA-2: 37.0;U-2 OS: 17.6" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (2.93e-1)" "unprognostic (5.33e-2)" "unprognostic (9.54e-2)" "unprognostic (4.16e-3)" "unprognostic (7.77e-3)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.17e-3)" "unprognostic (4.53e-2)" "unprognostic (6.43e-2)" "unprognostic (2.09e-2)" "unprognostic (6.24e-2)" "unprognostic (1.71e-2)" "unprognostic (9.38e-3)" "unprognostic (6.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.56e-2)" 6.6 4.0 7.6 1.1 10.5 0.3 3.7 6.0 7.3 4.4 0.9 0.6 0.3 0.5 3.1 1.3 1.1 1.7 5.0 8.3 12.2 0.8 0.8 43.1 1.9 13.8 11.5 0.3 0.4 15.1 0.5 1.2 14.8 4.1 1.0 19.6 2.4 4.4 10.5 3.1 0.6 0.7 18.6 0.8 0.8 3.9 12.6 4.0 9.3 6.8 0.9 1.2 1.2 17.9 0.1 0.0 1.9 0.0 0.0 0.0 2.2 0.8 0.1 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.7 4.0 0.2 5.5 0.5 5.6 0.0 0.0 0.0 1.5 0.1 3.1 0.3 0.1 40.4 0.0 0.1 0.0 0.0 0.5 0.4 0.3 0.0 37.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 2.1 0.1 1.9 0.5 0.0 4.8 0.0 1.0 0.0 0.0 17.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 10.5 6.0 7.3 8.3 12.2 13.8 11.5 14.8 18.6 12.6 17.9 1.7 240.4 12.6 0.0 0.0 0.0 4.7 0.0 13.1 20.5 6.2 3.4 6.2 0.0 19.8 0.0 4.2 0.1 0.0 0.0 0.0 0.9 0.2 0.4 1.5 1.6 0.0 0.0 0.0 0.0 0.3 10.9 0.0 0.1 1.3 2.2 6.1 0.0 5.1 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.6 3.0 0.0 0.0 0.2 17.8 0.0 0.0 0.0 1.5 0.1 1.2 0.0 3.1 0.0 0.2 3.6 1.6 0.0 8.7 3.3 0.6 1.6 1.5 0.0 0.1 0.3 0.8 0.4 1.1 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 AP1S3 ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223751686-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 52.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Cytotrophoblasts: 48.2;Pancreatic endocrine cells: 44.2;Urothelial cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.9;dendritic cells: 4.0;granulocytes: 4.9" "Cell line enhanced" "Detected in many" "CACO-2: 151.1;RPTEC TERT1: 56.8;RT4: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" 0.7 0.8 3.4 3.3 3.2 4.0 2.1 3.9 3.5 2.2 0.5 2.7 5.3 0.9 52.8 4.8 2.3 5.2 0.5 2.8 3.0 5.6 1.4 4.7 4.2 2.0 1.6 0.5 2.4 3.8 1.1 6.6 1.5 2.9 2.6 5.7 1.6 5.4 0.9 1.9 5.0 0.7 1.1 2.8 9.8 0.9 3.2 1.6 14.4 0.3 5.2 8.1 1.2 2.1 28.7 17.7 2.4 12.0 1.5 0.6 13.5 11.5 2.4 4.9 4.2 151.1 21.8 11.0 8.0 1.7 5.8 43.8 6.4 30.3 6.8 15.3 8.9 1.2 33.7 15.7 0.6 3.4 1.3 0.6 31.2 9.1 30.1 11.2 3.4 5.8 1.8 2.9 2.9 12.3 0.6 0.9 3.8 32.8 15.5 4.3 0.1 4.5 56.8 52.1 7.4 2.1 5.4 11.8 3.8 6.1 5.0 6.3 2.0 1.6 4.6 3.1 9.2 10.2 9.0 28.2 4.4 2.0 6.0 4.9 0.5 0.3 0.6 0.4 0.5 4.9 0.4 0.4 1.2 2.7 0.4 0.5 1.8 0.6 0.2 4.0 1.0 0.4 3.4 3.2 3.9 3.5 2.8 3.0 2.0 1.6 1.5 1.1 3.2 2.1 0.4 35.3 6.7 8.8 24.2 4.2 32.6 15.3 4.0 3.3 4.3 1.8 1.7 0.0 15.8 11.0 64.6 48.2 13.6 3.6 9.8 17.5 0.2 8.1 2.1 2.1 2.4 0.0 19.3 18.1 3.4 3.5 11.7 26.1 3.8 0.8 0.7 0.4 4.7 6.7 9.6 3.6 16.2 1.6 38.1 0.0 0.3 7.5 3.6 4.7 7.4 1.9 6.2 10.6 4.0 44.2 4.6 0.0 10.7 26.6 5.4 4.5 10.3 5.9 0.0 1.1 1.8 0.3 1.9 6.3 4.1 13.1 6.9 1.0 4.7 69.6 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 APH1A "APH-1A, CGI-78" ENSG00000117362 "Aph-1 homolog A, gamma-secretase subunit" Q96BI3 1 150265399-150269580 "Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037272 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "CAB037272: AB_476776" "unprognostic (1.00e-1)" "unprognostic (5.55e-2)" "unprognostic (8.84e-2)" "unprognostic (1.20e-3)" "unprognostic (4.92e-2)" "unprognostic (3.55e-2)" "unprognostic (2.75e-3)" "unprognostic (4.42e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.53e-1)" "unprognostic (6.99e-2)" "unprognostic (4.48e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.87e-1)" 73.5 93.9 59.3 60.5 63.4 78.7 97.8 60.8 60.7 79.6 58.3 100.6 82.2 60.5 84.0 118.6 83.2 69.0 71.0 55.3 59.1 78.6 132.2 83.6 80.7 67.2 62.3 88.6 92.2 110.3 56.5 72.4 62.2 62.0 95.4 24.4 92.7 68.1 58.8 120.6 80.4 54.8 65.7 99.2 95.7 34.8 64.7 72.9 95.7 63.2 90.7 77.8 84.0 63.4 226.4 95.6 113.7 175.8 140.3 115.0 148.3 82.8 171.4 183.7 190.9 78.2 251.5 125.3 116.9 146.2 90.9 180.2 98.8 143.6 127.2 114.0 122.8 93.2 61.3 101.7 173.6 173.1 136.4 145.0 198.7 124.5 147.6 132.7 201.8 128.3 104.1 208.4 119.0 280.7 118.8 101.5 127.5 163.7 158.0 135.9 116.0 203.8 136.1 151.9 93.2 210.7 81.9 133.8 172.0 105.6 174.5 303.8 115.5 104.8 99.4 102.8 147.1 297.0 263.0 113.0 89.4 180.6 116.7 9.7 10.6 8.2 11.1 9.4 11.8 8.6 7.6 7.4 9.9 6.8 7.0 8.4 9.7 12.1 10.5 9.3 3.8 9.9 59.3 63.4 60.8 60.7 55.3 59.1 67.2 62.3 62.2 65.7 64.7 63.4 80.6 22.4 25.5 15.3 91.9 65.8 86.2 107.1 74.6 23.3 92.9 72.6 24.0 70.1 56.1 82.8 8.4 132.8 77.4 110.9 33.2 131.6 7.1 26.3 40.6 77.4 75.6 44.2 6.8 157.2 143.9 60.3 50.0 49.7 35.5 74.9 71.7 68.2 159.8 37.0 7.9 107.4 71.2 125.1 95.0 7.7 60.3 88.7 62.2 12.2 119.2 59.6 113.3 13.0 10.7 140.4 84.7 40.6 84.6 102.8 81.7 49.7 22.1 17.5 26.3 57.1 38.8 17.2 16.4 83.7 81.8 165.4 71.4 62.4 114.0 122.0 APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved Vesicles NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" 217.2 130.2 125.6 144.0 126.0 196.5 192.3 164.7 157.9 170.4 252.6 209.9 272.4 176.6 138.6 134.2 167.6 201.8 271.6 131.0 153.2 359.9 334.8 391.4 77.5 130.9 137.5 180.8 136.0 291.5 87.1 324.8 133.1 287.7 176.7 540.8 135.3 291.0 65.9 113.3 226.6 211.5 135.4 95.7 149.7 54.9 157.9 81.5 607.8 85.2 56.8 199.1 129.6 152.8 216.7 170.3 307.1 281.2 1259.7 847.8 393.7 598.6 741.1 294.2 251.8 1300.5 1541.3 107.9 1515.3 1422.2 322.4 540.4 229.1 567.6 168.0 165.6 206.4 180.9 116.7 502.9 191.9 556.7 363.8 566.4 367.8 244.5 469.5 1520.2 912.7 34.1 180.7 228.9 495.2 205.7 26.9 245.3 182.8 256.8 301.1 70.0 69.8 105.5 758.9 589.6 109.9 239.0 706.9 368.0 92.0 535.8 582.2 489.5 1567.6 314.1 211.7 496.8 281.9 33.8 50.6 245.5 347.0 487.7 221.0 55.1 249.3 65.3 17.9 122.2 13.5 16.3 12.7 17.0 110.1 44.8 9.4 12.6 160.8 15.6 94.6 10.5 20.0 149.5 125.6 126.0 164.7 157.9 131.0 153.2 130.9 137.5 133.1 135.4 157.9 152.8 239.6 942.3 550.3 37.9 74.4 106.7 175.4 497.0 78.6 967.9 252.9 183.1 262.0 254.5 460.6 404.6 706.8 798.1 72.0 354.2 52.8 305.5 13.6 211.0 191.3 220.3 92.8 156.3 99.0 107.1 130.3 253.5 86.6 432.8 103.5 109.6 127.1 498.2 652.4 240.6 133.5 159.8 463.9 287.6 214.3 13.8 167.4 405.5 96.0 54.4 293.1 396.1 56.7 45.8 31.6 276.5 220.7 214.4 45.5 190.1 352.0 244.9 258.3 729.0 190.7 148.9 207.7 182.8 240.4 81.6 109.4 927.3 58.8 165.9 161.5 215.4 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOO "FAM121B, MGC4825, Mic23, MIC26, MICOS26, My025" ENSG00000184831 "Apolipoprotein O" Q9BUR5 X 23833353-23907938 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003187 Supported Approved Mitochondria,Cytosol "Secreted to blood" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA003187: AB_1079375" "unprognostic (2.53e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.86e-2)" "unprognostic (6.38e-3)" "unprognostic (3.45e-1)" "unprognostic (2.42e-1)" "unprognostic (6.18e-2)" "unprognostic (2.95e-1)" "unprognostic (6.45e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.22e-1)" "prognostic favorable (2.56e-6)" "unprognostic (2.53e-2)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (5.88e-3)" 9.0 23.7 55.8 9.0 58.0 7.9 13.3 58.1 76.3 13.1 67.8 17.3 14.4 10.6 19.6 12.6 20.8 9.3 65.1 57.9 58.4 46.5 18.2 8.6 11.7 58.8 57.0 9.4 14.2 62.0 29.2 10.9 57.3 13.7 18.8 52.8 19.7 15.0 45.9 7.7 12.0 12.0 57.0 8.4 17.7 16.8 56.8 14.0 20.3 73.2 11.6 11.2 8.1 57.1 36.5 32.7 53.9 37.8 8.8 19.9 8.3 17.9 21.9 37.4 38.8 19.3 17.0 31.5 21.9 16.5 48.5 29.3 68.5 35.7 41.2 33.4 48.7 15.9 28.6 31.1 20.8 40.9 17.1 22.2 20.7 41.2 30.4 20.1 26.6 38.8 22.9 33.2 35.1 34.6 41.2 43.0 49.2 47.5 52.7 31.5 26.6 75.6 74.1 18.4 36.4 26.5 39.0 36.7 39.7 52.4 63.6 17.9 6.5 23.9 14.6 86.6 27.9 26.3 50.5 28.7 38.5 19.8 35.8 14.8 4.8 1.4 12.6 15.9 16.6 10.8 13.7 12.5 14.0 10.2 10.9 10.7 3.0 10.3 16.0 16.6 14.0 7.7 55.8 58.0 58.1 76.3 57.9 58.4 58.8 57.0 57.3 57.0 56.8 57.1 7.4 16.0 11.5 61.7 11.8 14.0 17.0 74.3 11.4 20.4 14.3 17.0 61.8 21.5 28.3 23.9 14.6 17.2 11.3 12.8 180.0 28.4 25.9 56.0 13.0 10.1 7.2 20.8 61.4 16.0 8.9 11.7 13.3 24.4 3.8 14.2 7.9 13.9 22.7 20.2 76.5 17.0 44.7 14.6 12.0 15.7 11.5 9.9 28.4 74.0 34.2 50.0 8.2 43.7 76.5 10.2 20.0 15.8 14.8 14.1 24.0 80.6 106.9 32.4 6.6 10.8 22.3 26.1 53.2 18.9 7.0 12.4 9.5 17.0 22.3 16.8 APP AD1 ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880550-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 870.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 38.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 38.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 26000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" 249.9 498.0 413.0 157.4 457.6 134.4 447.5 413.1 572.4 264.2 396.8 357.2 226.4 281.1 293.3 178.6 308.1 350.8 389.0 456.2 405.3 532.5 298.2 279.4 78.9 425.0 481.9 306.2 323.5 278.6 155.4 451.9 448.7 260.6 328.5 209.3 270.7 343.6 107.5 218.6 200.3 379.9 419.7 154.4 213.5 165.6 426.4 159.2 469.9 176.0 78.2 304.9 151.7 523.5 388.7 489.9 538.4 448.5 707.7 869.8 559.8 757.1 1029.2 386.6 449.3 286.4 941.0 0.9 848.3 614.8 505.1 255.6 326.4 921.6 324.4 14.7 253.1 0.8 275.6 204.1 688.0 372.0 19.6 790.4 990.7 456.8 823.0 1584.3 1750.7 158.6 0.8 39.0 614.5 433.1 6.5 4.0 416.2 644.9 418.6 241.2 505.2 325.3 1283.3 270.1 267.3 385.6 824.0 549.0 393.4 720.0 482.4 400.1 1837.1 850.8 350.2 310.4 371.6 232.3 3.1 4.8 690.4 1.6 836.3 1.1 7.5 0.0 0.2 2.2 0.3 0.8 2.2 0.7 5.6 2.2 2.3 0.6 1.5 0.5 1.6 38.1 0.6 3.3 413.0 457.6 413.1 572.4 456.2 405.3 425.0 481.9 448.7 419.7 426.4 523.5 330.2 109.0 39.6 70.5 47.6 181.6 215.6 449.0 306.7 45.2 280.3 199.6 143.2 296.0 214.0 502.1 29.2 472.6 180.7 395.2 56.7 398.7 46.1 78.8 162.2 416.0 162.6 29.2 481.6 180.4 141.2 309.5 164.7 110.7 8.2 100.3 539.7 125.7 76.3 84.1 525.5 303.1 256.3 61.6 79.9 61.8 242.6 69.9 161.9 189.3 89.9 329.9 4.1 423.2 870.8 205.4 223.1 296.8 24.0 187.5 95.2 165.8 164.7 24.5 118.3 336.5 198.5 38.3 86.9 85.9 106.1 552.1 27.0 111.4 283.5 133.6 AQP9 "HsT17287, SSC1" ENSG00000103569 "Aquaporin 9" O43315 15 58138169-58185911 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "liver: 702.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 313.9;Macrophages: 82.1" "Cancer enriched" "Detected in many" 30 "liver cancer: 132.4" "Region enhanced" "Detected in many" "cerebral cortex: 14.4" "Immune cell enriched" "Detected in many" 20 "neutrophil: 1161.4" "Lineage enriched" "Detected in many" 20 "granulocytes: 1161.4" "Cell line enriched" "Detected in some" 29 "U-87 MG: 29.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA074762, CAB075684" Enhanced NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "CAB075684: , HPA074762: AB_2732267" "unprognostic (1.91e-1)" "unprognostic (1.92e-1)" "unprognostic (7.30e-2)" "unprognostic (2.67e-1)" "unprognostic (1.24e-2)" "unprognostic (4.15e-2)" "unprognostic (1.36e-3)" "unprognostic (2.28e-2)" "unprognostic (3.82e-2)" "unprognostic (2.03e-1)" "unprognostic (4.80e-3)" "unprognostic (6.98e-2)" "prognostic unfavorable (5.72e-11)" "unprognostic (8.78e-2)" "unprognostic (1.13e-2)" "unprognostic (1.25e-1)" "unprognostic (8.39e-2)" 18.2 0.8 0.8 72.9 0.9 67.5 2.4 0.9 14.4 1.3 0.8 0.9 0.2 1.2 43.4 1.2 7.1 5.3 1.7 3.2 0.5 0.9 702.7 22.2 0.6 0.7 1.0 0.5 1.6 5.6 0.3 6.2 4.0 0.9 0.3 0.4 1.1 0.7 0.5 22.0 0.9 6.4 0.6 42.7 1.5 0.3 6.9 1.8 0.6 7.5 0.8 32.6 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 29.7 0.1 0.0 0.2 58.4 1.2 0.1 17.5 0.1 0.5 0.1 0.0 1.8 0.1 0.1 0.0 1161.4 0.3 23.0 0.6 0.3 18.9 0.8 0.9 0.9 14.4 3.2 0.5 0.7 1.0 4.0 0.6 6.9 0.8 0.7 0.0 12.2 0.3 2.3 0.4 0.2 0.0 0.0 0.0 0.1 0.0 1.1 5.7 3.1 0.0 0.0 0.3 0.5 0.0 0.0 0.1 2.1 0.3 0.1 0.7 0.0 13.9 2.4 0.2 0.9 1.9 0.0 1.8 7.6 0.0 7.9 313.9 40.8 0.0 0.8 0.0 0.0 28.5 6.2 1.9 0.3 82.1 0.0 0.0 18.9 0.0 1.0 0.5 0.2 0.5 0.0 0.0 0.7 0.2 0.0 0.3 1.5 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.8 1.5 0.0 0.0 0.1 ARF1 ENSG00000143761 "ADP ribosylation factor 1" P84077 1 228082660-228099212 "Disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007742 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB007742: AB_562043" "unprognostic (9.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.30e-2)" "unprognostic (2.50e-3)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (8.95e-3)" "unprognostic (6.74e-2)" "unprognostic (2.96e-2)" "unprognostic (5.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.56e-1)" "unprognostic (8.57e-2)" "unprognostic (1.94e-1)" 268.3 282.5 213.8 176.7 222.5 426.9 241.9 188.1 261.9 249.1 215.1 259.8 242.6 266.6 193.1 304.7 247.5 189.2 340.0 242.7 231.3 257.0 324.7 298.2 185.0 200.6 201.6 237.3 327.6 296.9 299.1 276.9 207.6 244.0 177.3 96.7 355.2 203.9 330.9 237.3 240.8 176.2 196.6 251.4 265.6 193.9 218.9 184.4 240.3 206.4 154.7 229.0 233.1 206.4 476.6 321.6 257.4 257.9 289.9 362.6 425.7 409.5 433.0 444.3 386.8 383.6 442.7 239.9 428.8 438.3 204.6 298.8 316.4 399.4 219.4 355.3 506.8 234.3 209.8 386.6 559.5 342.1 333.8 350.4 476.7 408.6 427.0 374.1 443.3 267.0 456.0 533.3 431.4 341.8 350.0 495.9 331.7 656.7 643.0 279.0 228.1 750.6 315.1 242.1 362.6 320.0 265.9 790.0 466.8 87.8 543.9 681.0 406.0 324.6 256.5 479.4 626.8 498.5 301.0 331.1 445.9 285.0 670.6 1003.7 556.5 625.5 387.3 527.8 472.4 276.7 328.0 359.8 423.6 261.3 253.2 280.8 863.6 345.5 528.2 571.4 417.9 1082.4 213.8 222.5 188.1 261.9 242.7 231.3 200.6 201.6 207.6 196.6 218.9 206.4 276.9 173.1 185.2 25.8 205.1 262.6 281.7 248.0 104.2 114.3 209.1 172.0 139.8 125.8 208.1 115.8 45.9 373.7 267.8 487.8 230.9 422.7 236.3 164.6 218.7 247.2 230.1 173.8 42.3 404.5 565.8 227.3 142.8 240.8 198.3 128.8 152.4 124.8 409.4 158.2 41.1 436.9 213.6 198.8 256.2 429.9 229.2 300.1 300.6 35.6 356.0 162.2 214.2 30.7 40.7 400.2 407.2 227.2 282.8 344.6 370.1 173.3 180.7 80.2 230.1 149.6 416.0 321.1 155.7 158.3 286.0 676.7 224.9 174.6 335.2 370.0 ARFGEF1 "ARFGEP1, BIG1, DKFZP434L057, p200" ENSG00000066777 "ADP ribosylation factor guanine nucleotide exchange factor 1" Q9Y6D6 8 67173511-67343781 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023399, HPA023822" Supported Supported Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA023399: AB_1844981, HPA023822: AB_1844982" "prognostic unfavorable (8.76e-4)" "unprognostic (1.62e-1)" "unprognostic (4.60e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (4.52e-1)" "unprognostic (5.38e-2)" "unprognostic (4.67e-2)" "unprognostic (2.13e-3)" "unprognostic (1.31e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" 11.4 10.3 5.6 14.6 5.3 27.5 13.6 8.2 6.8 14.2 10.1 19.2 16.9 10.5 11.0 15.2 11.8 12.5 9.6 4.6 5.5 22.8 15.2 13.8 15.4 6.2 6.5 10.3 17.5 28.0 5.4 14.4 6.7 13.0 17.2 36.5 14.8 12.1 12.8 13.7 17.5 10.8 5.2 13.8 19.6 28.3 6.4 22.2 22.4 14.0 17.2 19.7 7.9 7.3 31.8 20.4 19.3 7.3 21.9 29.8 22.5 21.4 24.3 21.7 22.0 12.6 30.0 23.9 8.9 27.6 26.2 22.2 23.5 30.4 26.6 28.3 16.0 40.2 12.0 13.5 18.6 20.9 37.3 18.4 21.6 19.2 31.8 22.3 31.5 24.6 24.5 25.3 25.5 7.2 48.1 9.7 42.5 34.5 18.5 22.4 13.9 4.8 35.8 58.2 7.6 14.9 14.1 33.9 19.5 29.5 58.5 18.3 38.6 14.4 19.3 19.5 16.4 20.4 22.6 17.5 23.6 20.8 14.2 6.1 1.6 4.3 2.8 2.3 3.6 1.2 1.8 2.3 1.6 1.3 3.0 2.6 5.1 2.5 0.9 2.2 3.9 0.9 5.6 5.3 8.2 6.8 4.6 5.5 6.2 6.5 6.7 5.2 6.4 7.3 38.5 44.8 23.1 73.1 32.7 23.7 34.0 23.8 19.9 36.8 32.7 18.9 33.1 18.6 31.9 38.6 139.7 20.0 47.0 43.2 11.7 29.7 25.4 42.5 34.7 28.5 29.4 16.2 119.0 25.6 15.4 22.9 57.6 53.0 15.2 40.0 23.2 19.6 15.8 43.7 146.3 27.9 14.2 31.3 20.4 36.0 40.0 35.2 17.8 105.9 47.1 22.9 46.4 151.8 126.6 40.1 25.7 30.1 29.8 38.2 30.8 24.7 33.9 100.8 6.6 23.6 26.5 69.4 50.7 26.0 29.5 24.9 42.4 32.1 28.0 60.4 ARG1 ENSG00000118520 "Arginase 1" P05089 6 131470832-131584332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 1203.5" "Cell type enriched" "Detected in some" 22 "Hepatocytes: 991.4" "Cancer enriched" "Detected in some" 45 "liver cancer: 167.7" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 44.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 44.9" "Cell line enhanced" "Detected in single" "HL-60: 1.4" "Region enhanced" "Detected in single" "cerebellum: 2.4" "Low region specificity" "Detected in all" "HPA003595, CAB009434, HPA024006, CAB056159, CAB080011" Enhanced NA NA 9500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 2: Hepatocytes - Metabolism" "CAB009434: AB_2058955, CAB056159: AB_2665582, CAB080011: , HPA003595: AB_1078190, HPA024006: AB_1844987" "unprognostic (2.00e-1)" "unprognostic (2.09e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-1)" "unprognostic (9.95e-2)" "unprognostic (7.96e-2)" "unprognostic (7.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (7.55e-3)" "unprognostic (8.35e-2)" "unprognostic (1.25e-2)" "unprognostic (2.90e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (1.79e-2)" 2.2 0.2 0.1 0.3 0.2 292.0 4.8 1.0 0.5 0.3 0.2 0.2 0.0 0.1 0.0 2.1 1.9 0.0 0.8 0.3 0.2 0.3 1203.5 6.5 0.3 0.4 0.2 0.2 0.4 0.0 0.2 1.7 0.3 0.3 0.0 0.3 0.9 0.0 0.5 92.8 0.3 0.2 0.1 20.6 0.4 0.1 0.2 1.2 0.5 0.6 0.7 0.2 2.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 1.0 0.1 0.0 0.2 0.7 0.3 44.9 0.0 0.9 0.2 9.3 0.4 0.1 0.2 1.0 0.5 0.3 0.2 0.4 0.2 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.1 0.1 1.5 0.0 43.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 23.2 991.4 0.0 0.0 0.1 0.1 0.0 27.6 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 ARG2 ENSG00000081181 "Arginase 2" P78540 14 67619920-67651708 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Arginine metabolism, Immunity, Innate immunity, Urea cycle" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 220.0;prostate: 108.5;thyroid gland: 105.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 190.1;Collecting duct cells: 165.5;Glandular and luminal cells: 145.2;Proximal tubular cells: 220.9;Syncytiotrophoblasts: 601.3;Urothelial cells: 165.2" "Cancer enhanced" "Detected in all" "prostate cancer: 49.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 58.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000663, CAB009435" Enhanced Supported Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "CAB009435: AB_2059089, HPA000663: AB_1078192" "unprognostic (8.74e-3)" "unprognostic (3.06e-2)" "unprognostic (1.35e-2)" "unprognostic (2.29e-1)" "unprognostic (2.30e-1)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-3)" "unprognostic (4.62e-3)" "unprognostic (5.37e-2)" "unprognostic (4.66e-3)" "unprognostic (1.72e-1)" "unprognostic (9.39e-2)" "unprognostic (4.26e-1)" "unprognostic (2.31e-1)" "unprognostic (4.34e-1)" "unprognostic (1.26e-1)" 2.8 7.3 5.6 2.9 6.1 0.5 4.8 6.9 13.9 17.0 7.9 2.7 3.7 7.0 3.6 16.3 1.8 9.3 3.4 6.3 11.6 64.0 3.8 3.8 0.5 6.4 7.7 18.7 5.0 220.0 45.6 8.8 9.2 108.5 1.4 22.3 17.0 5.8 35.7 2.1 15.3 3.7 5.1 0.9 3.2 3.4 6.5 3.0 105.0 52.6 1.7 17.8 9.9 5.6 8.9 1.5 14.4 9.4 2.1 0.1 20.1 6.7 17.4 20.6 34.5 36.3 4.5 14.6 1.9 4.3 9.4 2.1 58.2 26.8 24.9 0.7 14.6 6.7 2.6 41.9 6.2 1.8 37.8 1.1 33.6 10.2 49.7 1.6 35.4 37.7 19.4 0.1 1.4 4.4 2.5 1.4 27.2 4.0 0.5 0.8 2.0 16.8 16.8 14.3 31.5 12.2 4.2 4.2 6.4 32.9 15.1 1.2 7.3 6.4 15.9 0.7 5.0 1.3 2.4 4.9 12.8 7.5 10.9 0.1 0.4 0.7 0.3 0.1 0.1 0.2 0.1 0.3 0.5 0.7 0.2 0.2 0.6 0.1 0.4 0.0 0.9 1.0 5.6 6.1 6.9 13.9 6.3 11.6 6.4 7.7 9.2 5.1 6.5 5.6 3.9 0.0 5.8 5.5 8.4 8.8 190.1 17.0 7.4 5.2 41.6 28.7 6.3 4.3 20.3 165.5 10.4 86.5 14.6 9.0 37.2 8.4 16.5 75.1 18.7 5.9 36.8 8.8 20.3 3.3 6.2 5.6 37.8 145.2 7.0 23.9 2.9 1.3 14.7 10.1 41.8 24.5 12.2 0.6 3.6 3.2 0.3 9.3 10.6 7.5 0.9 40.5 1.0 9.0 9.2 5.0 5.0 0.4 5.7 95.4 72.8 220.9 3.0 17.6 6.6 6.2 8.9 8.4 3.4 9.7 5.4 601.3 15.1 2.2 8.7 165.2 ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 99.8" "Group enriched" "Detected in many" 4 "Astrocytes: 1364.3;Microglial cells: 905.0" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.9;memory B-cell: 47.3;naive B-cell: 36.8;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.3;dendritic cells: 12.7;monocytes: 15.9" "Cell line enhanced" "Detected in many" "ASC diff: 109.0;ASC TERT1: 65.5;HHSteC: 63.6;HUVEC TERT2: 121.9;RPTEC TERT1: 67.2;TIME: 87.0;U-138 MG: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" 14.6 2.2 6.5 7.5 5.1 18.7 9.2 6.2 5.8 5.5 3.9 7.4 7.3 9.4 4.6 6.1 4.1 10.9 27.3 5.7 6.6 99.8 9.5 15.7 10.5 15.7 11.5 5.5 30.1 8.1 5.4 22.4 17.2 5.4 6.1 8.4 10.6 7.2 10.2 7.0 10.3 14.1 12.1 16.4 26.0 3.4 10.4 7.5 27.8 7.7 15.5 9.1 5.6 19.1 3.0 6.2 4.4 0.1 109.0 65.5 4.8 21.5 28.5 5.2 8.4 0.1 0.0 2.8 7.4 48.8 6.4 0.0 0.2 9.0 11.0 0.0 1.2 3.6 0.6 0.2 63.6 0.4 0.0 48.4 0.9 10.3 4.7 23.9 121.9 0.0 6.6 0.4 46.1 0.0 0.1 0.0 0.3 1.5 11.3 0.6 22.4 11.8 67.2 0.0 2.3 2.3 2.5 3.5 7.8 4.7 0.4 0.2 87.0 59.9 1.2 4.4 0.3 0.3 0.0 3.9 10.1 2.2 19.9 0.0 15.9 0.0 0.0 3.0 0.0 47.3 0.0 0.0 3.8 36.8 0.0 0.0 5.5 0.0 2.3 12.7 0.0 3.1 6.5 5.1 6.2 5.8 5.7 6.6 15.7 11.5 17.2 12.1 10.4 19.1 14.0 57.7 28.8 1364.3 142.1 8.2 3.9 35.6 10.2 6.6 1.2 4.7 26.4 47.1 18.3 46.0 6.2 54.8 9.9 1.0 226.9 9.4 30.5 1.2 12.9 9.5 2.4 0.0 12.2 11.8 26.2 24.7 25.0 1.4 1.3 6.7 4.2 9.5 10.5 111.0 51.3 3.3 6.1 33.7 21.3 8.8 16.8 26.3 19.6 905.0 34.0 27.7 0.0 27.2 21.8 7.4 2.9 12.4 2.0 2.3 0.2 205.9 24.8 6.6 6.6 50.0 21.3 8.1 5.9 4.0 6.3 232.9 4.1 18.4 5.0 1.9 ARL1 ARFL1 ENSG00000120805 "ADP ribosylation factor like GTPase 1" P40616 12 101393116-101407772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062656, HPA073012" Approved Supported "Golgi apparatus" NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA062656: AB_2684821, HPA073012: AB_2686564" "unprognostic (5.52e-2)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.61e-4)" "unprognostic (6.41e-2)" "unprognostic (3.15e-2)" "unprognostic (2.62e-3)" "unprognostic (1.69e-1)" "unprognostic (1.97e-1)" "unprognostic (4.82e-2)" "unprognostic (2.28e-1)" "unprognostic (4.54e-2)" "unprognostic (1.04e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-1)" "unprognostic (6.22e-2)" "unprognostic (3.46e-2)" 46.4 66.0 25.3 40.0 27.0 16.5 62.5 26.6 31.6 86.5 41.8 56.6 48.0 51.3 71.2 49.1 50.1 43.6 65.5 27.1 33.6 76.6 68.6 36.6 33.2 30.1 29.3 65.2 44.6 92.6 59.1 51.5 31.9 73.4 60.5 48.7 73.9 69.1 51.9 27.8 43.2 59.7 28.5 28.9 57.5 32.8 28.0 32.8 84.7 56.7 48.7 53.0 35.9 27.7 64.9 61.2 58.8 51.6 162.0 161.5 77.8 129.2 155.2 85.9 81.9 71.4 46.9 58.4 77.3 150.7 76.4 44.3 67.1 88.6 98.0 47.0 51.5 54.9 32.9 110.7 120.2 63.7 40.2 97.7 77.1 85.6 135.7 146.1 93.1 39.7 74.1 33.5 113.3 76.1 55.4 63.4 56.6 93.9 82.5 40.8 58.8 67.1 130.5 128.6 38.8 25.5 62.1 80.5 104.2 82.6 136.0 43.5 70.4 65.1 37.3 88.5 56.4 55.5 59.5 58.9 93.3 47.4 71.5 50.4 25.3 18.2 21.8 30.7 32.5 30.1 25.8 28.4 32.8 28.8 25.6 20.1 2.5 23.7 34.2 39.6 34.1 24.6 25.3 27.0 26.6 31.6 27.1 33.6 30.1 29.3 31.9 28.5 28.0 27.7 57.0 41.7 46.7 13.4 39.4 51.2 71.4 175.5 38.7 42.1 65.1 64.4 75.2 41.5 119.1 69.9 18.8 102.6 30.5 42.3 125.2 97.0 90.2 54.8 68.4 44.6 47.5 24.6 14.5 64.3 119.4 88.4 36.2 60.6 37.4 37.4 36.8 50.2 65.8 32.0 19.5 125.6 75.3 27.7 31.9 31.8 78.6 31.6 55.2 6.5 39.6 81.9 25.7 12.5 15.8 62.1 52.2 71.1 79.3 117.2 70.4 131.3 100.0 48.9 46.0 51.2 75.7 134.6 86.1 46.2 55.4 135.3 28.8 54.6 65.7 100.1 ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 96.3" "Cell type enhanced" "Detected in all" "Muller glia cells: 289.1;Rod photoreceptor cells: 318.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported Nucleoplasm,Centrosome NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 6: T47d - Mammary gland" "Cluster 46: Photoreceptor cells - Phototransduction" Centrosome Nucleoplasm "HPA036292: AB_10673618, HPA063596: AB_2685053" "unprognostic (1.36e-1)" "unprognostic (2.89e-3)" "unprognostic (4.19e-2)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (3.21e-1)" "unprognostic (3.99e-3)" "unprognostic (5.58e-2)" "prognostic favorable (1.71e-6)" "unprognostic (5.62e-2)" "unprognostic (3.09e-2)" "unprognostic (4.21e-2)" "unprognostic (1.03e-1)" 8.1 8.9 20.2 4.2 21.3 1.7 8.1 20.8 25.1 12.4 19.1 11.3 4.2 11.5 10.6 4.6 15.2 5.2 13.5 20.8 19.5 15.4 5.2 8.3 3.6 19.3 19.1 16.8 6.4 19.8 21.0 4.9 19.7 8.7 4.6 96.3 6.3 9.0 5.6 7.2 6.1 8.7 18.5 4.5 8.8 11.0 20.5 5.7 11.4 5.9 4.7 9.8 8.3 19.5 14.7 25.0 33.6 24.7 15.2 22.7 5.9 11.4 17.3 13.6 14.7 8.7 7.4 6.1 10.8 18.5 16.4 10.7 12.7 15.3 16.9 16.1 13.4 9.9 16.9 8.3 16.4 4.6 9.5 11.5 12.6 18.8 11.0 36.1 15.8 12.0 4.5 6.0 23.0 15.1 9.5 7.3 13.0 9.2 9.8 7.9 24.8 5.4 18.1 7.7 11.8 25.7 8.7 1.8 14.1 18.5 45.1 4.6 9.1 9.2 12.9 18.9 16.0 4.2 8.9 11.3 24.4 13.6 8.1 2.0 7.2 2.6 3.7 6.1 9.4 4.5 6.5 5.5 7.1 3.9 3.9 4.7 13.4 4.4 5.4 5.2 4.9 5.4 20.2 21.3 20.8 25.1 20.8 19.5 19.3 19.1 19.7 18.5 20.5 19.5 46.0 54.5 39.3 47.7 16.7 32.1 70.4 144.3 29.0 167.6 48.2 57.5 135.5 31.5 85.8 62.5 116.7 45.5 12.1 9.4 234.8 70.7 46.5 250.5 85.2 41.6 74.8 9.4 30.8 43.6 37.8 61.7 19.4 84.6 33.0 94.1 43.9 25.5 64.7 97.6 37.6 31.6 73.2 16.4 33.6 25.8 60.6 26.8 76.5 13.1 67.3 289.1 13.4 31.7 23.4 31.1 13.5 104.2 18.6 54.2 23.1 225.8 268.3 318.6 26.3 50.8 122.0 145.6 43.4 11.9 31.7 32.3 20.8 58.6 25.4 50.5 ARL6IP1 "AIP1, ARL6IP, ARMER, KIAA0069, SPG61" ENSG00000170540 "ADP ribosylation factor like GTPase 6 interacting protein 1" Q15041 16 18791669-18801572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045307 Uncertain Approved "Endoplasmic reticulum" NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA045307: AB_10961042" "unprognostic (2.42e-1)" "unprognostic (3.47e-2)" "unprognostic (4.07e-3)" "unprognostic (1.12e-1)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (2.58e-2)" "unprognostic (1.76e-2)" "unprognostic (3.88e-2)" "unprognostic (6.83e-2)" "unprognostic (1.91e-3)" "unprognostic (3.33e-2)" "unprognostic (1.13e-2)" "unprognostic (7.09e-2)" "unprognostic (4.60e-2)" "unprognostic (6.32e-3)" "unprognostic (5.36e-3)" 142.0 171.3 206.4 77.7 217.3 209.7 112.9 200.6 282.2 79.2 182.4 140.9 138.8 70.8 122.9 70.0 86.6 131.9 32.1 227.7 209.2 150.1 359.6 79.6 132.6 192.0 197.8 101.6 81.7 180.6 40.7 90.3 200.0 75.9 123.4 316.0 84.3 70.4 23.1 66.1 123.4 69.1 185.0 72.8 125.8 129.9 200.5 158.5 112.5 51.5 113.4 132.5 47.4 197.6 375.3 334.6 417.8 331.6 146.7 93.5 373.2 208.9 196.9 311.0 246.7 205.7 851.1 315.7 388.4 198.0 209.2 388.9 303.7 144.2 359.1 421.2 137.1 227.9 192.5 549.1 116.4 329.9 232.0 78.6 137.7 216.2 224.0 229.1 316.1 180.5 251.0 318.5 607.6 331.4 229.9 238.3 520.0 311.7 109.8 387.9 535.9 266.0 337.8 206.1 255.2 287.5 466.5 279.8 204.5 280.1 576.1 315.9 189.2 204.2 192.9 147.1 384.1 109.5 209.5 383.2 182.8 215.6 405.5 211.4 125.2 84.2 179.4 119.5 167.0 163.2 159.0 199.1 127.4 160.7 137.9 166.4 105.9 179.2 133.3 221.6 281.5 295.0 206.4 217.3 200.6 282.2 227.7 209.2 192.0 197.8 200.0 185.0 200.5 197.6 306.4 67.3 51.0 56.8 170.6 372.6 241.4 170.1 309.6 189.2 256.5 216.8 30.6 361.8 128.7 286.9 131.3 296.7 164.6 269.0 174.1 398.2 74.6 93.3 61.7 188.1 145.9 503.8 70.4 203.1 385.4 150.4 257.9 158.3 135.8 198.0 275.5 457.4 253.9 89.2 94.2 234.6 229.9 275.8 424.6 42.7 84.8 205.8 200.9 39.4 267.3 318.5 142.2 57.3 50.3 271.0 288.5 110.9 107.5 219.4 217.0 189.1 126.6 218.0 92.1 125.6 118.6 193.6 56.6 295.2 326.5 326.6 186.9 53.1 319.7 323.8 ARMT1 "C6orf211, FLJ12910" ENSG00000146476 "Acidic residue methyltransferase 1" Q9H993 6 151452258-151470101 "Predicted intracellular proteins" "DNA damage" "Hydrolase, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003004, HPA005819" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 410000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA003004: AB_1078358, HPA005819: AB_1845741" "unprognostic (5.16e-3)" "prognostic unfavorable (7.09e-4)" "prognostic favorable (4.14e-4)" "unprognostic (6.39e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-2)" "unprognostic (1.37e-2)" "unprognostic (9.47e-2)" "unprognostic (2.33e-2)" "unprognostic (2.16e-1)" "unprognostic (2.24e-1)" "unprognostic (3.28e-1)" "unprognostic (3.16e-2)" "unprognostic (1.49e-1)" "unprognostic (9.78e-2)" "unprognostic (4.12e-1)" "unprognostic (1.22e-1)" 17.1 16.0 8.5 15.3 9.5 5.5 25.0 9.6 12.2 16.1 8.3 16.6 18.9 16.0 16.1 12.0 12.6 11.3 16.8 8.6 10.0 41.5 37.6 19.5 21.0 9.0 9.1 11.9 6.8 11.6 5.3 22.2 9.1 12.2 17.6 16.4 7.6 11.1 19.0 8.8 14.5 14.9 9.6 12.8 14.1 14.1 9.8 15.6 27.7 22.6 18.5 17.3 8.1 9.0 24.6 18.4 37.9 34.2 30.3 47.4 60.9 44.8 39.1 36.9 48.4 47.8 19.7 36.2 29.5 31.8 33.7 24.2 112.7 33.5 61.7 40.6 34.9 26.0 21.7 55.9 37.8 50.1 31.7 38.2 23.3 49.3 29.2 30.6 52.8 27.0 38.5 44.3 46.4 101.8 31.7 47.4 64.4 23.7 15.3 41.0 32.7 28.6 112.6 31.2 15.6 10.2 37.5 34.9 23.8 67.4 98.9 38.6 44.6 17.9 25.0 66.8 36.3 21.1 28.5 43.7 31.7 60.7 21.6 53.8 26.9 52.0 13.5 34.5 18.1 17.5 17.4 14.5 22.9 14.7 15.9 14.8 22.1 21.0 33.4 8.5 25.1 21.1 8.5 9.5 9.6 12.2 8.6 10.0 9.0 9.1 9.1 9.6 9.8 9.0 16.3 25.6 40.4 6.5 13.2 0.0 8.4 0.0 11.4 10.0 33.5 16.3 18.6 14.3 6.2 23.9 8.4 31.7 12.6 10.6 45.0 19.5 1.4 19.4 29.3 10.6 4.9 6.5 11.4 17.8 39.0 14.2 12.2 23.3 3.8 7.7 15.4 48.7 35.4 8.4 9.8 8.9 0.0 34.0 0.0 3.1 19.3 23.6 0.0 5.6 36.0 17.3 18.6 6.6 8.9 19.5 7.2 14.7 15.2 5.4 18.6 79.3 10.9 20.9 0.0 6.7 14.3 25.2 14.8 11.1 0.0 36.0 14.0 15.5 10.7 9.6 ARPC1A "Arc40, SOP2Hs, SOP2L" ENSG00000241685 "Actin related protein 2/3 complex subunit 1A" Q92747 7 99325898-99366262 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 442.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA004334 Approved Approved "Cell Junctions,Cytosol" NA NA 760000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" Cytosol "HPA004334: AB_1078215" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (6.22e-3)" "unprognostic (1.93e-2)" "unprognostic (8.38e-3)" "unprognostic (1.95e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (2.52e-2)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.89e-2)" "unprognostic (7.88e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (7.07e-2)" "unprognostic (1.83e-1)" 74.4 82.9 61.6 39.7 63.3 40.4 63.2 60.1 71.9 69.8 71.9 80.7 92.8 60.1 80.9 124.6 75.5 53.3 121.7 78.7 73.9 65.9 77.4 62.2 41.9 64.6 67.7 81.5 63.8 65.4 62.1 54.3 71.7 56.9 78.2 33.0 66.6 55.5 48.0 84.5 84.9 57.2 60.8 52.7 99.1 42.4 68.4 39.2 78.8 47.1 44.9 61.6 74.9 62.9 265.3 144.3 155.1 73.6 144.2 242.4 133.5 185.5 216.1 185.5 184.4 164.4 301.7 92.3 270.5 226.7 273.8 110.6 208.0 270.8 221.5 46.7 186.4 49.7 99.9 137.1 156.1 59.2 63.7 227.6 149.1 237.8 252.0 220.0 310.8 75.9 125.9 105.6 289.8 398.6 99.4 78.5 150.5 295.3 326.1 58.1 107.8 113.9 142.0 162.7 161.7 138.3 180.9 260.2 255.9 264.2 130.2 88.4 239.3 239.0 211.0 424.7 302.1 39.6 80.0 130.7 206.6 130.1 320.2 111.7 49.9 88.8 24.2 80.8 19.3 30.8 23.1 31.5 43.0 28.8 30.0 22.6 63.7 30.7 86.1 31.9 33.5 26.9 61.6 63.3 60.1 71.9 78.7 73.9 64.6 67.7 71.7 60.8 68.4 62.9 124.3 51.3 55.5 20.9 45.2 41.4 139.5 249.1 54.7 38.0 107.2 131.6 46.7 95.8 130.1 58.8 18.8 189.6 27.3 196.2 135.0 213.6 32.1 55.0 43.7 96.4 74.2 68.8 31.6 276.9 345.8 70.6 140.2 57.4 13.3 141.4 135.0 75.8 84.6 33.7 28.0 209.4 132.2 77.5 26.1 24.6 66.8 56.0 80.0 26.2 68.6 79.8 42.2 19.1 28.4 442.5 191.6 67.4 52.4 151.5 295.7 155.5 102.2 40.1 184.1 59.1 188.4 171.6 130.0 88.9 47.9 129.7 29.8 87.7 166.3 280.7 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 ASPG C14orf76 ENSG00000166183 Asparaginase Q86U10 14 104085686-104115582 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.4;liver: 151.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 21.4;Distal enterocytes: 21.2;Granulosa cells: 66.8;Hepatocytes: 93.9;Proximal tubular cells: 49.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA069761 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 40: Granulosa cells - Unknown function" "HPA069761: AB_2686191" "unprognostic (1.45e-2)" "unprognostic (7.43e-3)" "unprognostic (2.38e-3)" "unprognostic (1.30e-1)" "unprognostic (7.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.72e-2)" "unprognostic (3.47e-2)" "unprognostic (1.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.50e-1)" "unprognostic (1.10e-1)" "unprognostic (8.75e-2)" "unprognostic (7.98e-2)" "unprognostic (3.85e-1)" "unprognostic (1.52e-2)" "unprognostic (2.32e-2)" 1.1 1.4 0.1 0.2 0.2 0.0 0.7 0.0 0.4 5.4 0.2 4.7 1.5 2.2 1.1 34.0 6.2 0.1 102.4 0.3 0.3 12.8 151.1 2.3 0.0 0.4 0.6 11.4 0.2 0.8 2.3 1.8 0.2 0.3 1.9 0.3 2.8 0.1 0.5 9.9 0.5 1.2 0.0 0.2 3.1 1.1 1.1 0.1 5.9 0.0 3.7 2.3 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.5 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.5 0.4 0.3 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.3 0.3 0.4 0.6 0.2 0.0 1.1 0.0 0.0 6.4 1.7 0.3 0.5 1.8 0.2 0.7 0.0 1.1 0.6 0.8 21.4 2.8 2.4 0.0 0.0 0.2 0.0 21.2 3.9 0.0 0.4 0.7 0.1 0.5 1.8 0.0 0.1 0.2 0.2 4.3 4.6 0.7 0.0 66.8 3.6 93.9 0.2 5.0 0.1 16.0 0.0 1.6 0.3 0.7 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.4 7.6 1.2 0.0 0.1 0.9 49.7 1.6 0.3 0.0 0.0 0.6 0.3 1.5 8.4 9.1 0.5 0.3 3.9 5.4 3.0 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ATCAY BNIP-H ENSG00000167654 "ATCAY kinesin light chain interacting caytaxin" Q86WG3 19 3879864-3928082 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 46.6;pituitary gland: 25.6;retina: 17.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 128.5;Excitatory neurons: 67.0;Horizontal cells: 47.1;Inhibitory neurons: 82.2;Oligodendrocyte precursor cells: 94.0" "Cancer enriched" "Detected in some" 8 "glioma: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 7.3;SCLC-21H: 13.2;SH-SY5Y: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017755 Enhanced NA NA "Cluster 11: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "HPA017755: AB_2669655" "unprognostic (7.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.63e-2)" "unprognostic (1.91e-1)" "unprognostic (7.11e-2)" "unprognostic (1.27e-1)" "unprognostic (9.12e-2)" "unprognostic (3.05e-2)" "unprognostic (4.89e-2)" "unprognostic (9.83e-4)" "unprognostic (7.22e-2)" "unprognostic (8.78e-3)" "unprognostic (1.78e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-2)" "unprognostic (2.67e-1)" 0.1 6.9 32.1 0.6 34.6 0.3 0.0 0.5 46.6 0.9 0.0 1.1 0.5 0.1 0.1 0.2 0.0 0.2 0.1 29.8 36.1 0.1 0.0 0.1 0.2 17.8 13.8 0.1 0.3 0.0 25.6 0.1 16.7 1.8 0.3 17.6 0.1 3.2 1.2 0.3 0.6 0.2 3.3 0.1 0.4 0.2 17.3 0.0 0.1 0.0 0.0 0.1 0.6 24.6 0.5 0.1 2.7 0.3 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.6 0.5 0.2 0.0 1.5 0.4 0.2 0.0 0.0 0.2 0.2 0.8 1.1 0.2 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.5 0.5 0.1 0.2 0.2 0.4 7.3 0.1 0.1 0.2 0.4 0.2 0.1 0.2 13.2 9.3 0.2 0.2 0.1 1.2 0.2 0.2 0.5 0.3 0.6 0.4 0.7 0.3 0.3 0.2 0.3 1.3 0.2 0.6 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.1 0.1 0.1 32.1 34.6 0.5 46.6 29.8 36.1 17.8 13.8 16.7 3.3 17.3 24.6 0.2 0.0 3.4 3.3 0.6 0.6 0.8 0.0 0.0 128.5 0.2 0.1 1.9 2.8 0.0 0.0 22.9 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.9 0.7 0.0 0.0 67.0 0.0 0.2 1.1 0.0 0.8 7.0 0.1 0.7 0.1 0.1 47.1 82.2 0.2 0.0 0.6 2.6 0.0 0.0 0.5 3.6 5.6 0.1 5.4 2.1 94.0 3.9 0.0 0.0 0.4 0.0 0.5 0.0 0.1 0.0 18.7 0.0 1.9 0.7 0.7 1.7 0.0 0.4 0.0 0.6 0.0 0.1 0.4 ATG16L1 "APG16L, ATG16A, ATG16L, FLJ10035, WDR30" ENSG00000085978 "Autophagy related 16 like 1" Q676U5 2 233210051-233295674 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012577, HPA063900" Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" Cytosol "HPA012577: AB_1845155, HPA063900: AB_2685146" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (3.57e-2)" "unprognostic (2.22e-3)" "unprognostic (1.89e-1)" "unprognostic (4.49e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.85e-2)" "unprognostic (6.66e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.93e-2)" "unprognostic (1.41e-1)" "unprognostic (2.41e-1)" "unprognostic (2.08e-1)" 7.6 7.8 7.0 3.8 7.5 14.3 8.8 7.9 8.4 8.1 12.8 11.1 5.0 9.6 5.5 11.6 7.1 3.3 10.7 7.3 6.6 9.2 15.1 7.6 5.8 6.5 6.3 8.5 8.6 5.3 5.5 4.0 6.9 12.1 5.2 5.6 11.5 4.3 19.9 17.2 11.1 5.2 6.3 11.5 11.1 13.5 6.5 5.9 11.2 6.1 5.2 11.5 8.2 7.7 13.3 12.2 4.9 8.5 12.4 8.0 14.0 11.4 9.3 9.6 8.9 8.9 9.7 3.1 3.7 8.9 14.3 7.7 9.8 6.4 9.8 6.2 7.7 7.1 9.1 14.6 9.1 5.6 9.0 5.3 9.1 11.5 8.7 7.2 9.0 4.7 7.6 2.9 10.2 9.3 6.7 11.2 19.1 14.1 17.6 4.8 10.3 2.6 9.9 8.4 8.8 6.5 7.8 8.5 8.5 7.4 5.3 7.1 10.7 6.2 5.4 9.6 10.3 6.5 3.9 6.1 10.5 5.7 10.2 0.0 1.7 2.9 4.8 1.4 3.7 2.0 3.1 4.4 1.4 2.2 3.5 3.5 1.2 4.1 4.7 0.7 3.8 2.1 7.0 7.5 7.9 8.4 7.3 6.6 6.5 6.3 6.9 6.3 6.5 7.7 6.1 6.4 8.2 5.2 7.4 9.1 4.6 5.2 3.4 8.4 12.0 6.6 5.6 7.2 11.6 5.5 4.2 4.6 20.9 13.9 5.9 8.3 1.2 16.4 10.9 6.4 9.0 3.8 31.0 6.7 6.2 5.2 8.2 31.8 9.5 6.4 6.1 10.2 5.6 1.7 25.6 5.1 6.1 6.3 5.7 1.7 4.1 5.1 10.6 8.4 6.6 7.1 4.1 11.6 21.4 16.8 8.0 3.8 8.1 7.1 9.2 5.6 11.5 19.5 6.6 5.8 6.9 11.0 17.6 7.3 13.2 3.7 19.2 5.1 8.4 6.0 ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 657.9;Spermatocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" 33.1 38.7 41.4 49.1 50.1 94.1 34.7 51.3 53.5 28.3 38.2 38.2 38.2 24.7 24.7 34.8 23.2 24.7 33.3 39.7 46.8 41.6 43.3 31.1 48.4 49.1 48.2 25.6 41.8 44.8 30.6 33.6 48.5 23.2 40.3 29.1 29.4 28.3 29.5 29.8 36.6 29.9 48.2 48.2 37.7 85.3 45.6 51.2 42.2 33.6 46.3 38.7 26.3 55.7 105.0 55.9 51.5 52.6 66.6 54.5 57.5 89.8 65.3 86.9 78.9 78.9 60.6 130.3 66.6 78.0 106.6 74.1 84.9 78.0 120.9 22.8 40.9 82.0 52.3 51.0 102.9 145.2 67.0 50.6 58.3 85.5 130.2 56.8 82.2 81.2 71.6 108.8 92.9 91.4 86.4 68.2 56.3 135.8 109.7 74.9 45.9 110.5 72.6 56.1 88.1 34.7 74.7 70.5 109.5 48.4 79.8 107.5 66.7 92.3 75.8 39.4 80.1 70.2 72.0 201.3 84.4 133.2 69.4 64.4 167.7 121.9 39.4 258.8 49.4 61.8 48.0 49.2 169.4 59.2 46.2 46.3 174.2 50.5 327.9 36.3 75.6 138.2 41.4 50.1 51.3 53.5 39.7 46.8 49.1 48.2 48.5 48.2 45.6 55.7 45.6 48.1 39.0 10.1 53.3 74.1 42.4 74.3 37.5 22.5 32.0 50.2 86.2 37.1 51.3 25.8 12.5 73.1 45.3 47.0 117.4 73.7 657.9 37.9 40.8 54.1 31.2 90.0 11.7 86.1 85.0 42.6 36.7 45.2 39.9 42.0 40.0 40.0 121.3 18.5 11.4 53.3 75.3 106.3 131.1 146.5 42.6 134.8 69.4 11.2 185.8 42.1 54.6 13.0 33.7 70.9 49.2 43.2 70.4 39.1 76.0 87.5 37.3 22.2 59.2 45.5 77.6 341.0 119.7 57.4 70.6 122.3 55.0 68.6 69.8 54.2 ATG4A "APG4A, AUTL2" ENSG00000101844 "Autophagy related 4A cysteine peptidase" Q8WYN0 X 108091668-108154671 "Enzymes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036374, HPA064759" Uncertain Approved "Actin filaments,Microtubules" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 6: Erythroid cells - Oxygen transport" Microtubules "Actin filaments" "HPA036374: AB_10672354, HPA064759: AB_2685346" "prognostic unfavorable (1.36e-5)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.52e-1)" "unprognostic (1.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "unprognostic (2.83e-3)" "unprognostic (2.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.62e-2)" "unprognostic (4.09e-1)" "unprognostic (1.03e-3)" "unprognostic (7.53e-2)" "unprognostic (2.98e-1)" "unprognostic (5.02e-3)" "unprognostic (1.20e-2)" 8.1 8.5 4.9 7.8 5.2 9.1 7.7 5.2 6.1 7.6 10.4 12.1 12.8 4.7 11.6 8.9 5.6 7.7 11.8 4.7 5.2 14.1 18.1 8.9 8.2 5.3 5.0 2.8 17.2 12.4 6.1 8.0 5.4 5.9 13.1 5.7 13.0 7.1 18.5 5.8 11.4 7.7 5.0 7.7 11.2 2.4 5.7 11.2 11.4 18.6 11.1 8.9 5.1 5.4 13.0 6.5 4.1 7.8 38.2 13.2 5.1 17.5 11.2 9.1 10.6 5.3 6.9 14.0 15.7 14.0 14.5 6.0 11.9 13.0 13.5 24.1 12.9 6.0 10.3 3.7 8.4 13.0 18.8 13.4 13.9 11.1 4.8 8.4 84.9 19.5 18.5 43.5 16.6 12.8 12.1 11.9 7.8 23.6 18.4 8.2 6.9 20.3 13.2 11.3 5.9 4.5 11.2 13.9 7.9 12.4 7.0 11.5 24.0 5.7 2.6 19.1 9.8 20.2 24.0 15.1 11.1 14.6 8.1 28.1 7.8 15.1 11.7 11.3 8.4 9.2 8.9 11.4 10.6 9.9 7.1 12.0 2.4 12.3 7.8 5.4 10.3 8.7 4.9 5.2 5.2 6.1 4.7 5.2 5.3 5.0 5.4 5.0 5.7 5.4 13.6 3.2 10.3 9.1 8.1 5.1 4.9 13.5 2.8 3.2 7.0 4.6 17.4 7.2 12.8 5.5 4.2 6.2 12.4 19.1 27.4 9.6 7.0 10.6 7.4 12.9 6.7 36.7 7.9 17.9 7.5 4.6 8.2 6.0 3.8 3.3 9.7 15.4 9.0 1.7 8.4 9.0 30.5 4.1 3.6 10.0 2.8 7.3 14.2 4.7 6.7 10.3 18.6 7.1 11.6 16.6 8.0 7.5 23.5 5.6 14.7 24.7 17.2 5.0 0.0 4.5 6.9 2.4 3.9 5.9 5.3 10.4 12.0 6.2 5.6 7.3 ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 932.7;Proximal tubular cells: 1449.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (5.55e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (3.34e-2)" "unprognostic (2.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.72e-1)" "unprognostic (7.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-1)" 102.0 136.9 173.3 65.9 183.6 73.8 100.1 180.8 201.1 84.4 181.9 84.7 81.8 73.7 98.0 112.1 64.6 63.6 107.4 170.0 189.7 217.1 260.9 80.3 142.9 181.9 184.7 57.8 57.1 180.6 81.2 69.8 183.6 100.2 64.3 24.9 93.0 74.6 53.6 102.8 83.0 75.9 184.9 124.4 76.1 72.9 185.6 82.6 119.3 39.5 128.2 91.7 84.2 192.8 112.0 181.9 104.4 73.1 275.1 224.2 136.6 197.7 225.8 197.2 267.3 248.2 235.8 224.9 233.3 345.7 437.1 102.4 129.2 502.5 161.3 143.9 220.3 98.7 118.4 255.1 254.1 137.5 108.5 291.3 105.0 246.0 161.1 144.7 295.3 138.5 83.4 642.7 305.1 276.6 102.3 304.0 59.8 249.8 382.3 61.4 120.0 350.0 190.6 98.1 136.2 80.0 169.3 476.6 763.4 117.2 234.2 165.3 328.5 201.0 159.4 246.9 345.9 522.6 513.4 136.2 271.7 92.3 846.1 154.6 207.9 199.4 75.1 247.6 69.0 98.6 67.3 66.2 171.3 68.3 53.0 58.0 155.3 97.0 177.2 217.8 103.5 117.3 173.3 183.6 180.8 201.1 170.0 189.7 181.9 184.7 183.6 184.9 185.6 192.8 209.1 57.7 56.6 8.1 93.2 67.7 79.8 204.5 70.0 22.7 250.1 246.5 112.1 165.8 102.2 211.5 14.6 146.0 65.6 213.6 541.9 207.6 178.9 121.1 171.1 183.2 150.7 104.1 6.4 159.1 218.7 127.3 96.8 135.3 73.0 117.8 236.7 932.7 671.2 25.2 9.1 171.1 164.8 221.4 166.0 321.1 83.0 230.4 238.3 4.7 436.7 185.7 88.6 5.5 22.7 318.1 238.7 103.4 170.4 124.2 727.0 1449.1 108.5 24.9 92.1 69.0 235.2 81.9 156.0 153.1 106.4 118.8 55.4 96.6 152.7 122.2 ATP13A4 "DKFZp761I1011, FLJ37958" ENSG00000127249 "ATPase 13A4" Q4VNC1 3 193398967-193593111 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 64.5;parathyroid gland: 58.4;thyroid gland: 51.9" "Group enriched" "Detected in many" 4 "Astrocytes: 409.4;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 23.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051932 Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA051932: " "unprognostic (4.97e-2)" "unprognostic (1.50e-3)" "unprognostic (4.86e-3)" "unprognostic (2.52e-3)" "unprognostic (2.72e-2)" "prognostic favorable (3.91e-4)" "unprognostic (1.55e-1)" "unprognostic (3.99e-3)" "unprognostic (2.65e-1)" "unprognostic (1.36e-1)" "unprognostic (4.39e-2)" "unprognostic (1.34e-1)" "unprognostic (4.29e-5)" "unprognostic (1.91e-1)" "unprognostic (1.70e-1)" "unprognostic (5.75e-3)" "unprognostic (2.00e-1)" 0.1 0.3 19.5 0.2 20.9 0.2 22.7 18.1 20.1 2.8 28.2 2.0 0.3 0.1 64.5 20.1 2.4 4.6 0.1 18.0 17.0 0.7 0.6 27.3 0.4 18.5 21.5 0.3 5.3 58.4 4.8 0.1 17.9 0.1 3.4 2.5 7.2 2.4 0.5 16.9 0.3 0.1 15.2 0.3 9.6 0.5 21.6 0.3 51.9 0.0 4.8 0.1 6.7 15.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.6 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 19.5 20.9 18.1 20.1 18.0 17.0 18.5 21.5 17.9 15.2 21.6 15.8 0.2 64.1 30.5 409.4 1.1 0.1 0.0 1.7 0.0 1.6 6.1 3.6 0.4 11.5 15.3 0.0 0.0 1.2 0.5 1.6 0.0 3.3 0.4 4.0 0.7 0.1 0.0 0.0 5.8 0.2 0.1 0.2 17.3 6.4 1.3 0.3 1.4 0.1 0.2 1.7 10.9 1.9 0.0 0.3 0.5 1.0 0.0 0.5 1.8 13.1 0.0 0.5 0.0 163.3 20.6 1.3 1.7 0.4 0.2 0.0 0.0 0.4 8.5 1.0 0.0 0.1 0.2 0.7 1.5 2.2 1.6 0.7 0.9 0.1 2.2 0.1 ATP1B1 ATP1B ENSG00000143153 "ATPase Na+/K+ transporting subunit beta 1" P05026 1 169105697-169132722 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 1337.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 1723.3;Proximal tubular cells: 1070.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 919.7;RPTEC TERT1: 513.0;SH-SY5Y: 382.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012911 Enhanced NA NA 2100000 "Cluster 27: Non-specific - Gene expression" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA012911: AB_1845173" "unprognostic (4.20e-2)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.85e-2)" "unprognostic (1.95e-1)" "unprognostic (5.34e-2)" "unprognostic (2.22e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (6.80e-2)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "prognostic favorable (7.08e-7)" "unprognostic (1.11e-1)" "unprognostic (5.48e-2)" "unprognostic (1.97e-3)" "unprognostic (9.39e-2)" 12.4 146.9 197.7 48.0 216.2 4.4 79.4 370.0 451.1 37.5 369.3 246.1 336.6 108.8 64.3 159.8 48.8 178.7 160.5 326.4 332.1 1337.8 180.1 92.6 8.5 558.7 264.3 58.1 178.5 732.7 79.8 44.1 540.2 48.6 201.1 99.3 314.1 72.6 342.9 67.0 284.4 96.6 248.8 52.6 402.1 46.3 375.1 19.2 330.2 337.8 84.0 101.2 52.1 382.2 89.7 215.8 73.3 56.3 15.9 3.3 23.8 45.3 33.1 41.7 43.3 276.8 183.5 0.1 158.3 35.1 50.8 102.4 38.1 83.2 45.1 1.1 16.6 5.7 152.6 138.9 26.6 4.0 7.5 9.1 21.1 31.8 42.5 79.7 40.5 6.6 1.3 1.4 52.6 38.0 7.9 16.0 28.1 919.7 47.4 1.3 89.3 15.6 513.0 118.6 54.3 382.5 263.1 271.3 12.5 85.4 55.7 9.8 92.0 35.2 90.4 60.9 159.3 4.8 6.8 2.0 42.0 13.9 47.9 13.2 1.0 0.2 2.7 3.2 1.5 1.5 3.3 1.3 9.3 0.2 1.0 1.1 0.3 6.2 1.1 0.4 10.1 1.4 197.7 216.2 370.0 451.1 326.4 332.1 558.7 264.3 540.2 248.8 375.1 382.2 14.4 240.4 251.5 79.0 18.4 52.5 156.5 490.4 153.1 86.9 274.2 166.5 147.3 664.8 425.7 1723.3 14.6 4.8 21.0 817.1 923.4 629.9 3.8 199.6 11.6 18.6 160.9 6.9 344.7 591.9 9.0 78.7 353.7 190.6 23.4 89.0 45.7 273.3 385.3 580.5 602.3 296.7 370.2 99.5 676.1 9.0 89.8 101.5 247.3 81.5 27.1 23.4 1.0 94.5 514.7 377.9 666.4 149.0 16.9 84.4 646.8 1070.2 332.5 64.9 6.6 93.6 32.5 10.6 66.9 142.8 31.7 9.9 48.2 111.8 436.0 322.8 ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401606-118431496 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1407.2;Distal tubular cells: 2907.4;Hofbauer cells: 1367.3;Proximal tubular cells: 2520.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044629 Approved Supported Mitochondria NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA044629: AB_2679028" "unprognostic (1.70e-1)" "unprognostic (2.40e-2)" "unprognostic (2.21e-1)" "unprognostic (5.45e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-2)" "unprognostic (3.90e-2)" "unprognostic (8.19e-2)" "unprognostic (5.13e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (7.41e-2)" "prognostic favorable (4.09e-5)" "unprognostic (6.26e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (3.05e-2)" 119.8 137.2 154.2 103.3 158.5 165.6 132.5 158.5 184.3 81.1 168.3 153.6 146.4 79.3 143.3 116.9 96.5 68.1 329.8 157.2 160.8 205.1 154.5 77.9 150.0 155.5 153.1 112.0 110.9 140.7 49.5 83.7 154.0 83.5 164.3 100.8 133.9 92.2 340.7 55.3 118.2 95.2 153.6 86.0 112.3 46.9 155.5 204.1 87.5 373.6 183.1 105.3 41.5 154.7 163.1 87.9 209.3 183.1 167.6 198.0 200.1 149.0 175.9 138.4 146.6 259.9 259.9 314.3 352.7 167.5 206.2 190.4 204.4 214.8 155.3 247.6 138.0 472.8 112.5 197.4 175.3 279.3 210.2 207.1 203.4 169.0 162.9 164.1 189.8 216.6 227.4 253.1 199.5 305.8 365.2 497.3 130.1 427.9 224.0 247.0 174.9 422.9 371.1 260.3 184.3 161.9 232.3 361.1 161.9 221.6 303.0 307.7 172.8 123.0 144.7 109.2 190.9 112.8 184.8 402.1 93.8 353.0 154.7 325.4 437.2 299.0 241.8 360.8 339.7 462.7 398.8 321.5 481.2 378.5 472.9 379.7 214.8 357.2 333.3 534.3 464.5 1112.1 154.2 158.5 158.5 184.3 157.2 160.8 155.5 153.1 154.0 153.6 155.5 154.7 324.3 362.2 364.1 0.0 211.2 0.0 0.0 0.0 0.0 0.0 893.9 1061.2 0.0 0.0 166.5 610.6 0.0 1407.2 378.3 0.0 2907.4 748.6 0.0 449.8 327.9 188.9 0.0 0.0 0.0 986.0 935.6 204.7 0.0 404.6 258.6 368.2 0.0 0.0 1367.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 427.7 0.0 0.0 678.1 0.0 0.0 0.0 0.0 922.2 0.0 0.0 94.9 0.0 0.0 2520.3 188.0 0.0 0.0 0.0 217.5 0.0 0.0 0.0 0.0 1001.4 224.2 370.0 0.0 0.0 ATP6AP1 "16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3" ENSG00000071553 "ATPase H+ transporting accessory protein 1" Q15904 X 154428633-154436516 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB015218 Uncertain NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "CAB015218: " "prognostic unfavorable (2.40e-4)" "unprognostic (1.95e-2)" "unprognostic (2.06e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (1.84e-3)" "unprognostic (4.99e-3)" "unprognostic (2.57e-1)" "unprognostic (1.10e-2)" "unprognostic (1.84e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.07e-1)" "prognostic favorable (5.26e-8)" "unprognostic (2.45e-1)" "unprognostic (4.66e-2)" "unprognostic (3.39e-1)" "unprognostic (1.62e-1)" 56.3 93.5 108.3 43.1 109.2 59.1 56.7 99.6 118.0 59.6 123.6 61.5 48.4 54.2 145.1 85.2 60.0 46.0 92.7 116.2 115.4 104.3 51.4 96.8 46.9 114.0 96.8 63.3 86.6 176.0 110.4 77.9 121.6 85.1 57.0 74.0 87.4 54.8 53.8 83.6 57.4 49.0 104.6 94.7 70.4 47.5 104.2 40.9 81.9 54.4 42.5 63.7 60.9 121.6 110.1 101.6 88.2 146.2 145.7 77.4 162.2 78.5 116.6 122.5 176.1 93.4 135.1 64.7 337.8 177.1 216.5 112.3 133.8 71.9 76.6 58.6 135.1 37.5 113.7 100.0 170.6 60.9 260.2 98.1 126.7 112.4 68.2 139.5 177.0 47.8 45.6 176.4 84.7 158.1 43.6 96.8 32.1 171.0 100.8 66.6 59.1 170.7 139.9 87.3 84.6 89.7 72.6 289.7 159.3 87.3 123.1 157.8 135.5 87.4 79.0 151.1 135.6 256.3 311.8 77.0 104.4 132.8 90.2 246.6 295.1 363.9 147.3 313.8 148.6 91.7 118.4 127.8 376.7 113.6 107.1 117.8 326.9 140.3 255.6 215.9 155.2 216.9 108.3 109.2 99.6 118.0 116.2 115.4 114.0 96.8 121.6 104.6 104.2 121.6 39.4 38.5 57.5 17.0 32.3 30.2 42.7 122.4 25.6 105.8 58.5 42.2 37.7 54.3 102.1 97.5 47.9 145.1 40.1 84.3 19.6 65.4 3.1 52.5 33.7 50.1 89.0 35.8 17.0 52.5 104.5 48.8 36.7 57.4 77.3 51.8 54.3 46.6 246.3 129.5 24.2 59.0 160.7 143.6 88.2 5.5 41.3 130.3 72.9 15.0 79.9 68.4 27.8 22.1 26.4 42.4 67.5 42.5 61.7 34.1 63.7 49.1 112.5 69.2 65.7 35.7 45.5 64.4 10.7 31.6 32.8 196.5 36.3 74.1 54.6 47.2 ATP6AP2 "APT6M8-9, ATP6IP2, ATP6M8-9, M8-9, PRR, RENR" ENSG00000182220 "ATPase H+ transporting accessory protein 2" O75787 X 40579372-40606848 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Congenital disorder of glycosylation, Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 765.1" "Cell type enhanced" "Detected in all" "Hofbauer cells: 702.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003156 Approved NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "HPA003156: AB_1078245" "unprognostic (1.45e-1)" "unprognostic (3.80e-3)" "unprognostic (1.30e-1)" "unprognostic (7.19e-2)" "unprognostic (8.58e-3)" "unprognostic (1.29e-1)" "unprognostic (1.63e-3)" "unprognostic (2.01e-2)" "unprognostic (1.00e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.01e-5)" "unprognostic (2.34e-1)" "unprognostic (2.08e-1)" "unprognostic (1.62e-2)" "unprognostic (2.86e-2)" 81.2 71.5 85.6 60.6 86.5 124.4 95.1 76.4 116.9 106.1 72.4 82.9 32.1 86.6 91.3 70.1 75.6 79.7 55.1 90.8 90.2 165.6 96.8 87.3 67.4 80.4 79.8 68.9 53.3 765.1 30.7 106.9 83.4 86.6 89.0 99.3 39.4 97.9 18.4 71.9 47.8 124.7 84.6 69.0 49.1 40.4 87.6 72.0 177.1 40.1 72.5 97.7 41.4 98.7 83.9 117.5 78.7 106.7 472.6 312.4 47.9 182.4 274.1 127.0 152.9 68.0 142.6 48.4 88.1 257.0 141.3 86.6 114.0 136.0 168.2 92.7 97.7 57.5 100.2 66.5 172.0 104.6 111.6 259.6 175.2 154.2 121.4 200.3 168.1 46.1 63.8 130.7 201.7 109.8 45.5 93.7 73.4 140.8 112.7 43.8 132.6 161.6 182.8 96.8 55.2 51.9 185.8 111.7 118.4 284.2 147.8 97.1 172.5 175.0 91.3 207.7 62.8 38.0 70.7 46.2 139.1 93.0 138.5 269.0 511.1 404.8 156.1 364.9 164.3 106.7 157.3 161.9 341.3 110.3 174.8 159.3 255.9 141.2 378.6 124.2 167.2 692.9 85.6 86.5 76.4 116.9 90.8 90.2 80.4 79.8 83.4 84.6 87.6 98.7 102.3 57.7 65.6 36.2 65.4 97.3 135.4 254.3 46.1 155.8 74.1 61.2 30.4 94.4 175.4 138.0 54.2 173.4 109.6 70.3 62.6 146.6 3.6 97.2 115.5 94.7 57.1 62.3 44.8 59.1 106.3 156.5 34.7 124.5 87.5 63.7 96.0 64.0 702.2 188.4 56.3 54.6 349.9 279.5 263.3 9.5 117.4 222.0 149.4 28.1 185.4 193.0 72.1 40.2 40.6 64.0 58.9 151.2 74.8 97.9 61.0 106.4 127.4 93.3 105.2 116.7 138.7 106.7 43.1 60.0 99.9 174.4 100.3 188.2 63.6 121.1 ATP6V0E1 "ATP6H, ATP6V0E, M9.2" ENSG00000113732 "ATPase H+ transporting V0 subunit e1" O15342 5 172983771-173035445 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.24e-1)" "unprognostic (3.08e-1)" "unprognostic (3.61e-1)" "unprognostic (1.51e-1)" "unprognostic (5.34e-2)" "unprognostic (1.54e-3)" "unprognostic (2.25e-3)" "unprognostic (1.66e-2)" "unprognostic (1.39e-1)" "unprognostic (6.63e-2)" "unprognostic (1.47e-1)" "unprognostic (8.33e-2)" "unprognostic (1.01e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" 265.1 267.9 135.7 158.7 142.2 89.7 223.2 145.3 192.0 220.8 181.0 204.6 127.0 199.1 634.0 228.9 193.3 163.3 262.4 133.0 154.4 338.2 237.0 253.3 191.4 156.2 145.1 189.3 179.4 145.9 314.2 171.7 154.5 232.3 154.6 45.8 245.0 154.1 225.0 178.9 189.5 157.9 150.3 270.1 233.3 93.4 144.5 130.1 241.2 137.6 188.3 227.2 199.1 158.3 249.4 263.6 85.5 259.5 777.8 310.6 200.6 475.7 444.6 235.3 361.6 299.2 376.6 107.0 663.0 567.4 622.2 174.6 173.4 342.2 260.6 741.8 170.9 100.8 242.1 287.3 379.5 192.9 340.6 413.0 413.3 270.7 149.1 284.0 287.0 116.9 67.3 306.3 519.3 487.6 121.7 278.0 99.2 195.8 228.5 128.8 121.9 193.0 471.5 312.4 123.9 82.8 208.6 255.7 400.5 235.1 282.5 265.5 430.2 553.0 125.9 397.8 405.3 263.2 587.5 120.2 299.5 318.6 185.2 2395.6 1150.2 1781.5 671.3 865.7 620.8 1088.5 761.2 706.6 734.6 951.6 734.7 761.7 2193.1 655.2 852.2 1099.7 853.8 2168.0 135.7 142.2 145.3 192.0 133.0 154.4 156.2 145.1 154.5 150.3 144.5 158.3 226.2 131.4 226.0 23.5 271.9 293.2 327.6 796.7 177.0 17.7 261.1 275.0 199.9 248.8 444.4 518.6 6.2 492.6 279.9 279.8 324.8 619.5 24.0 296.8 188.8 269.7 213.1 138.2 22.9 366.4 553.7 308.2 112.7 394.7 254.1 217.1 258.5 373.6 720.3 37.0 21.6 206.2 565.6 452.1 606.7 40.8 342.3 439.7 368.2 37.5 897.8 295.3 409.9 22.6 44.8 555.1 375.0 335.9 185.1 463.0 362.9 687.5 332.6 21.5 243.3 110.2 238.4 124.6 138.2 219.4 284.6 842.7 275.9 214.7 205.2 405.9 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747033-113812056 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 463.7;Late spermatids: 870.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 79.2" "Group enriched" "Detected in all" 6 "dendritic cells: 38.8;granulocytes: 79.2;monocytes: 37.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favorable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 18.1 32.2 40.1 21.6 46.4 16.6 24.5 14.7 53.0 25.3 62.4 22.1 18.5 14.2 15.1 22.7 19.0 20.9 9.0 47.5 58.5 92.7 36.4 24.5 25.1 39.6 23.0 11.3 20.9 60.1 17.1 24.5 39.0 20.9 22.5 58.7 37.5 14.9 7.9 25.0 15.9 15.8 16.9 26.5 22.1 18.1 28.4 22.9 40.8 11.0 28.0 19.6 14.2 21.9 61.7 27.4 33.9 29.7 70.0 30.9 36.0 32.7 49.4 33.7 46.1 52.4 48.3 50.4 75.5 48.0 37.3 39.1 77.5 43.2 43.8 23.1 21.4 44.8 39.3 40.6 57.6 33.2 50.0 42.0 29.1 43.7 30.2 52.0 55.7 25.1 52.0 37.0 50.5 40.5 24.4 14.9 42.8 42.9 34.3 20.8 24.6 57.4 92.5 58.0 65.4 24.1 57.3 38.6 44.9 46.4 58.5 26.6 51.4 31.1 23.1 21.7 19.8 38.4 44.5 46.2 61.1 41.2 35.3 26.8 37.0 12.8 6.3 27.7 5.9 8.2 5.6 6.0 38.8 6.8 5.4 6.2 79.2 9.2 23.9 10.8 8.1 16.7 40.1 46.4 14.7 53.0 47.5 58.5 39.6 23.0 39.0 16.9 28.4 21.9 18.8 28.9 35.0 43.4 24.2 30.3 15.9 30.3 23.9 94.1 27.9 17.1 10.4 31.5 32.9 99.3 41.7 22.0 20.8 38.3 82.2 29.5 463.7 41.7 24.5 26.8 55.8 49.6 119.4 27.5 22.6 17.9 20.9 100.6 10.8 19.4 36.0 74.3 74.3 101.0 107.7 25.4 197.4 104.7 73.3 870.3 18.0 70.9 46.2 34.7 82.8 45.6 11.3 54.3 53.2 27.1 30.5 23.0 23.6 25.6 24.1 80.8 38.3 44.4 6.6 15.3 21.6 28.7 15.7 40.8 47.9 43.9 19.0 25.8 27.2 26.8 ATP6V1D "ATP6M, VATD, VMA8" ENSG00000100554 "ATPase H+ transporting V1 subunit D" Q9Y5K8 14 67294371-67360265 "Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 365.9;Proximal tubular cells: 365.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031515, HPA057316" Enhanced Approved Nucleoplasm Yes No 19000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA031515: AB_10600785, HPA057316: AB_2683409" "unprognostic (1.10e-1)" "unprognostic (7.35e-2)" "unprognostic (1.59e-1)" "unprognostic (7.10e-3)" "unprognostic (1.52e-1)" "unprognostic (7.64e-2)" "unprognostic (7.78e-3)" "unprognostic (1.19e-1)" "unprognostic (2.32e-1)" "unprognostic (3.05e-2)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "prognostic favorable (7.60e-13)" "unprognostic (2.78e-1)" "unprognostic (3.18e-2)" "unprognostic (1.41e-2)" "unprognostic (1.44e-2)" 43.4 116.2 98.0 32.2 103.2 28.8 43.8 91.8 119.7 40.3 101.8 52.9 40.4 34.3 72.5 96.7 48.1 38.7 136.6 107.2 103.5 129.8 51.7 37.5 33.3 96.1 98.4 26.1 36.2 88.8 65.8 43.4 106.7 55.7 57.5 78.0 45.1 49.8 78.5 40.4 41.7 46.4 95.1 24.3 43.8 42.5 99.7 52.4 89.5 108.5 46.3 54.5 54.1 99.6 242.5 64.7 96.2 62.4 80.2 82.8 73.5 199.1 109.4 145.8 109.1 76.2 85.2 24.8 73.9 155.1 105.3 89.2 72.6 117.9 195.7 82.5 50.8 23.4 74.5 51.0 144.0 24.9 64.8 65.1 77.7 105.4 73.1 131.4 97.6 58.6 50.2 55.3 206.6 78.5 66.5 46.2 60.7 104.6 83.3 48.8 84.2 32.8 171.2 104.3 120.2 49.8 122.9 65.4 145.6 96.2 98.3 53.4 123.8 162.4 121.6 77.6 120.1 55.8 46.1 33.4 150.2 44.1 96.1 106.7 77.5 92.8 48.5 78.8 40.8 39.9 53.2 52.7 83.4 42.0 41.6 41.7 94.0 48.9 83.5 73.9 78.8 65.0 98.0 103.2 91.8 119.7 107.2 103.5 96.1 98.4 106.7 95.1 99.7 99.6 31.3 54.5 63.0 13.4 27.6 96.2 66.6 112.3 26.2 60.0 44.8 41.8 160.8 55.8 85.0 82.8 54.2 92.3 51.4 91.6 365.9 125.9 190.3 120.8 44.1 40.7 54.4 78.1 22.7 48.9 85.5 51.5 42.3 71.8 41.2 39.8 27.5 45.8 132.0 87.5 21.0 49.4 175.0 44.6 61.0 97.9 32.9 62.2 80.0 6.5 58.5 89.4 47.4 9.5 22.1 121.5 78.7 50.8 21.3 65.9 80.9 365.5 184.1 94.2 13.1 44.5 64.1 100.1 61.5 78.4 138.4 205.9 40.8 71.6 40.6 113.8 ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587706-114598915 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli NA NA 96000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoli Nucleoplasm "CAB004615: AB_2258908, HPA042898: AB_2678217" "unprognostic (3.85e-1)" "unprognostic (1.71e-1)" "unprognostic (2.03e-1)" "unprognostic (1.24e-1)" "unprognostic (2.23e-1)" "unprognostic (1.84e-3)" "unprognostic (2.49e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (3.47e-3)" "unprognostic (9.40e-3)" "unprognostic (4.13e-2)" "prognostic favorable (1.73e-7)" "unprognostic (2.44e-2)" "unprognostic (1.50e-1)" "unprognostic (9.11e-2)" "unprognostic (3.92e-2)" 79.5 140.2 70.5 80.5 71.1 131.4 108.4 74.0 101.1 85.0 85.0 70.5 59.4 92.4 177.3 132.5 71.3 64.6 93.0 72.1 79.4 138.1 125.9 84.9 115.4 75.4 79.1 106.2 72.5 172.9 135.1 91.2 80.2 132.7 65.5 91.2 111.9 55.1 124.0 98.1 69.2 60.6 71.5 93.9 121.1 75.4 75.6 104.2 99.2 113.0 100.8 106.8 94.0 75.4 83.6 71.0 153.2 38.8 111.0 84.5 148.3 125.2 86.6 88.5 63.4 92.3 94.8 74.2 106.8 80.0 183.2 179.0 105.6 84.6 79.3 63.2 73.8 72.3 84.4 143.4 156.8 173.1 135.1 105.2 227.9 72.7 87.3 104.1 91.0 123.1 136.0 164.4 131.6 159.0 164.6 113.6 187.0 222.2 126.8 159.0 95.0 126.7 195.2 128.4 113.8 156.3 159.7 284.0 487.6 143.9 235.0 202.5 118.9 80.1 68.9 132.3 142.0 213.6 474.5 139.6 106.8 97.2 112.0 490.1 327.8 495.0 212.6 331.2 264.9 549.6 288.8 255.8 255.0 501.7 374.7 305.5 405.4 255.4 348.4 401.5 398.9 756.7 70.5 71.1 74.0 101.1 72.1 79.4 75.4 79.1 80.2 71.5 75.6 75.4 230.6 160.3 176.6 19.6 353.9 519.0 492.9 1068.9 277.7 170.5 470.4 494.1 151.6 163.0 629.7 331.1 41.7 346.1 268.2 198.5 970.5 374.1 85.7 381.6 223.8 227.7 360.7 157.6 35.0 263.6 336.5 247.0 231.4 594.9 267.4 156.8 219.2 337.1 548.1 164.9 37.4 346.8 1133.2 350.1 517.8 60.3 306.0 382.4 494.5 20.6 699.7 360.9 261.6 20.1 22.9 430.5 218.1 250.9 255.0 686.5 176.7 1021.5 426.3 158.6 236.7 155.6 393.0 400.6 326.7 361.4 576.7 757.4 304.0 280.3 201.6 852.2 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 ATP9A "ATPIIA, KIAA0611" ENSG00000054793 "ATPase phospholipid transporting 9A (putative)" O75110 20 51596514-51768390 "Enzymes, Predicted membrane proteins, Transporters" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 112.2;Inhibitory neurons: 87.1;Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Cell line enhanced" "Detected in many" "EFO-21: 74.0;SK-BR-3: 69.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020699, HPA035630" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "CAB020699: , HPA035630: AB_10669526" "unprognostic (5.19e-2)" "unprognostic (5.28e-2)" "unprognostic (3.46e-1)" "unprognostic (1.05e-1)" "unprognostic (3.76e-1)" "unprognostic (1.37e-1)" "unprognostic (3.76e-2)" "unprognostic (4.79e-2)" "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "prognostic favorable (5.67e-5)" "unprognostic (5.82e-2)" "unprognostic (5.81e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" 30.6 11.5 55.9 5.8 63.2 2.7 14.1 26.0 63.7 8.5 0.0 18.5 13.6 12.4 18.5 12.9 24.8 12.0 11.6 67.1 52.2 9.2 7.5 9.7 3.7 41.8 50.0 18.8 15.1 29.5 16.2 4.9 46.8 20.5 16.4 20.5 25.7 15.5 16.3 6.8 17.8 12.7 33.2 2.9 20.4 18.8 53.4 7.4 28.1 17.6 3.1 11.9 9.8 48.7 25.8 21.7 17.2 38.8 49.0 36.8 0.4 9.1 17.1 5.8 1.7 50.4 51.9 0.0 74.0 37.2 29.1 20.1 22.9 12.9 5.7 20.2 7.1 0.0 23.2 19.8 6.7 0.0 0.1 12.1 25.6 1.3 3.5 13.3 31.4 4.7 0.1 0.2 6.6 35.9 2.0 0.2 3.1 25.4 27.0 4.1 0.0 0.1 11.6 35.7 32.7 23.2 36.3 69.9 13.2 6.0 13.5 0.6 20.7 48.1 12.7 19.1 3.9 0.0 0.3 0.8 12.7 0.1 4.4 4.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.7 55.9 63.2 26.0 63.7 67.1 52.2 41.8 50.0 46.8 33.2 53.4 48.7 4.8 16.0 13.6 43.4 0.5 2.9 14.6 13.8 4.0 35.9 16.0 11.3 12.7 31.5 19.1 18.4 4.2 0.4 2.5 64.3 1.9 21.4 0.8 20.4 4.7 9.8 55.2 0.8 112.2 17.2 0.5 9.9 26.5 28.8 1.3 14.3 11.0 12.8 5.4 43.7 87.1 34.9 18.3 2.2 2.1 3.4 13.4 12.1 3.6 40.3 0.2 5.0 2.1 60.8 90.3 24.6 28.8 23.3 2.1 33.7 36.3 1.4 34.9 7.4 6.6 10.1 8.0 1.2 8.2 9.9 4.1 0.3 2.3 0.7 24.8 27.3 ATPSCKMT "FAM173B, JS-2" ENSG00000150756 "ATP synthase c subunit lysine N-methyltransferase" Q6P4H8 5 10225507-10249897 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Cytotrophoblasts: 5.9;Extravillous trophoblasts: 4.1;Fibroblasts: 2.3;Hofbauer cells: 7.8;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074513 Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "HPA074513: AB_2686698" "prognostic unfavorable (1.32e-6)" "unprognostic (8.87e-3)" "unprognostic (1.23e-3)" "unprognostic (1.20e-1)" "unprognostic (9.24e-2)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-2)" "unprognostic (6.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-1)" "unprognostic (9.06e-2)" "unprognostic (5.61e-2)" "unprognostic (1.03e-1)" 8.5 10.3 12.4 5.4 13.0 3.9 6.6 13.5 15.5 5.7 13.8 7.4 6.1 6.9 9.1 5.8 6.5 7.2 6.9 11.7 14.3 9.0 9.9 5.1 7.8 13.2 13.6 6.3 5.1 17.1 9.9 4.1 13.2 8.8 8.7 5.0 7.4 8.3 6.7 5.8 5.6 7.5 12.0 4.5 6.2 5.7 13.4 6.9 8.8 7.4 6.8 7.1 5.3 14.8 14.1 13.3 13.9 13.8 12.7 9.8 4.8 20.4 9.2 9.2 8.0 14.1 21.0 16.8 35.2 13.0 27.7 9.6 19.6 17.0 15.8 30.9 13.2 14.5 47.6 11.4 9.7 22.8 16.5 9.1 18.3 17.4 5.5 11.8 19.7 17.8 19.9 18.0 26.6 11.9 11.6 20.2 9.1 29.9 17.4 15.8 9.7 15.9 24.6 16.5 11.1 10.9 69.3 24.5 12.2 10.5 25.7 23.2 11.2 22.4 13.9 14.2 14.9 11.9 14.5 19.7 14.1 25.3 9.0 3.2 5.8 8.1 4.3 6.7 5.3 3.8 4.2 5.5 5.8 2.6 4.1 5.4 2.2 3.8 5.5 2.1 5.4 2.6 12.4 13.0 13.5 15.5 11.7 14.3 13.2 13.6 13.2 12.0 13.4 14.8 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 5.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212027-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051353: AB_2681451" "unprognostic (4.58e-2)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.59e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.73e-2)" "unprognostic (5.35e-3)" "unprognostic (2.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-1)" 86.5 79.6 57.3 48.0 62.2 72.2 109.9 62.7 70.8 108.8 73.8 82.0 59.8 82.1 343.6 59.1 123.7 68.0 129.7 56.9 61.8 133.2 72.0 74.8 63.8 64.5 60.1 119.6 120.2 120.5 40.7 74.8 64.2 81.5 92.3 56.7 107.7 107.3 142.6 55.9 59.4 72.7 61.7 64.4 73.3 96.1 59.3 68.4 114.1 139.1 66.2 79.2 38.1 66.4 126.9 145.6 82.4 144.9 408.7 242.2 126.9 75.6 227.6 93.8 87.0 116.2 184.4 63.5 126.6 201.3 134.8 108.7 75.9 132.2 81.1 101.2 77.2 75.0 79.4 182.6 185.9 65.2 93.6 192.5 275.5 80.2 179.3 213.3 123.7 110.5 76.4 191.7 144.5 161.8 78.8 174.0 124.0 263.3 123.0 70.5 218.7 293.2 161.2 68.6 90.7 136.5 89.7 112.4 122.8 118.4 96.3 98.5 82.8 147.9 87.4 54.1 77.8 302.4 249.6 166.2 152.9 124.8 143.5 188.4 242.1 206.7 198.5 223.2 202.9 278.5 227.6 226.9 251.1 271.1 238.8 219.6 54.1 189.1 240.7 293.2 277.5 443.1 57.3 62.2 62.7 70.8 56.9 61.8 64.5 60.1 64.2 61.7 59.3 66.4 143.0 60.9 82.1 7.8 96.4 102.2 176.4 306.4 112.1 44.2 135.0 155.7 163.2 114.4 169.9 143.5 18.8 273.0 95.0 68.6 181.9 182.5 159.6 113.7 109.5 118.4 91.8 47.1 4.3 191.3 328.2 200.0 57.6 96.8 90.7 124.6 113.2 82.7 209.4 28.6 6.6 134.6 205.4 110.7 104.8 223.9 196.3 100.9 176.1 9.4 157.6 153.9 92.7 9.5 13.9 126.1 123.1 141.1 177.0 109.6 135.1 212.0 160.8 48.9 52.6 103.8 137.8 374.7 162.6 110.2 100.7 250.5 93.5 167.8 137.6 153.7 ATRN "DPPT-L, MGCA" ENSG00000088812 Attractin O75882 20 3471018-3651118 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 101.6;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 89.5;Oligodendrocytes: 85.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008853 Approved Approved Cytosol "Secreted to blood" NA NA 27000000000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA008853: AB_1078248" "unprognostic (6.42e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (2.52e-1)" "unprognostic (5.27e-2)" "unprognostic (1.65e-1)" "unprognostic (3.99e-2)" "unprognostic (4.28e-1)" "unprognostic (3.40e-2)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "prognostic favorable (2.19e-6)" "unprognostic (3.71e-2)" "unprognostic (9.49e-2)" "unprognostic (2.77e-1)" "unprognostic (3.91e-2)" 12.8 19.1 10.5 10.3 12.2 8.6 17.2 9.3 13.2 16.5 8.9 11.8 55.8 11.8 15.6 10.4 11.7 13.9 19.1 13.4 12.2 23.9 62.8 14.4 7.5 8.0 8.7 14.0 20.2 40.1 8.7 22.6 9.0 12.8 12.3 24.2 13.9 13.2 11.6 14.9 33.4 14.9 11.3 13.8 24.0 16.6 10.8 7.8 32.3 14.2 9.6 15.7 9.1 15.8 40.8 37.6 21.9 18.4 37.9 61.5 28.1 26.6 37.5 27.4 23.1 16.3 27.1 0.0 17.5 37.4 33.8 55.6 15.0 58.1 36.4 4.5 12.8 12.7 10.0 35.1 22.8 27.2 8.3 33.1 46.0 29.0 27.8 34.3 36.0 8.7 20.2 19.2 27.0 11.7 11.1 10.4 14.7 13.2 22.3 9.2 50.9 30.8 24.8 28.5 12.9 20.2 26.7 48.9 36.3 21.3 26.2 25.5 44.7 29.0 17.0 30.8 26.6 13.4 20.1 0.1 17.9 17.9 29.6 3.6 3.2 2.0 2.3 2.8 1.0 1.4 1.2 1.4 2.8 1.7 2.0 1.7 0.0 1.5 3.1 2.6 1.8 1.0 10.5 12.2 9.3 13.2 13.4 12.2 8.0 8.7 9.0 11.3 10.8 15.8 11.1 16.0 10.4 70.2 5.8 6.4 4.3 14.1 6.8 22.5 9.9 8.8 12.6 20.0 10.3 11.0 37.5 7.4 8.0 6.5 1.9 8.2 7.1 9.9 15.1 11.1 9.6 7.4 101.6 14.6 8.4 12.7 20.4 11.8 7.0 39.3 17.9 50.9 10.4 37.0 101.1 10.7 4.1 14.2 6.7 5.4 12.5 11.5 7.2 64.6 10.1 11.8 5.2 89.5 85.7 10.0 14.3 7.9 11.4 7.0 34.6 7.3 10.2 20.1 32.9 14.3 10.9 21.3 21.1 8.5 7.2 5.1 5.8 21.0 12.6 5.2 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 ATXN7L3B lnc-SCA7 ENSG00000253719 "Ataxin 7 like 3B" Q96GX2 12 74537835-74545430 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056612 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA056612: AB_2683190" "unprognostic (3.43e-3)" "unprognostic (1.07e-1)" "unprognostic (4.76e-2)" "unprognostic (3.20e-2)" "unprognostic (3.68e-1)" "unprognostic (9.26e-2)" "unprognostic (1.81e-3)" "unprognostic (7.12e-2)" "unprognostic (9.55e-2)" "unprognostic (6.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.49e-1)" "prognostic favorable (2.25e-6)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-2)" 13.8 18.5 27.5 15.2 28.2 20.1 22.2 26.2 30.7 18.2 25.5 17.3 20.3 21.1 25.0 13.9 33.2 14.2 17.9 28.9 32.0 23.6 20.5 16.6 21.0 25.6 27.2 32.3 22.9 25.9 15.9 22.8 28.8 22.3 19.1 46.3 23.3 21.1 20.9 17.9 18.9 18.0 25.3 19.1 38.3 8.8 30.7 30.5 24.5 20.9 22.8 14.1 12.0 27.4 21.5 16.6 54.3 34.6 33.6 31.4 23.2 20.1 20.0 23.3 18.1 19.3 11.6 31.0 15.6 20.0 15.6 21.1 28.4 19.4 19.2 28.8 22.3 41.5 17.3 29.4 32.0 41.6 8.4 36.4 44.3 17.9 29.2 40.6 27.3 35.5 52.1 15.2 19.3 31.0 46.2 29.5 31.0 29.4 15.8 35.7 29.4 28.1 21.5 34.8 85.1 53.7 22.7 26.6 32.6 35.0 62.8 26.9 23.6 22.3 19.5 13.4 12.7 18.0 18.0 39.9 9.6 15.0 22.8 17.3 9.5 12.7 5.1 8.9 6.2 4.2 7.7 5.7 8.9 4.8 13.1 7.4 2.7 8.4 12.1 4.9 6.1 9.1 27.5 28.2 26.2 30.7 28.9 32.0 25.6 27.2 28.8 25.3 30.7 27.4 40.1 73.7 46.3 10.1 33.4 18.4 42.1 25.2 56.9 87.9 40.6 44.7 53.0 41.5 48.3 38.6 33.3 58.7 54.8 33.1 31.3 39.6 0.7 76.1 67.5 39.9 36.2 36.2 17.2 32.8 34.0 41.7 98.4 37.5 46.2 35.8 27.8 27.5 22.9 52.2 18.2 38.7 10.2 23.9 10.7 2.0 37.6 25.9 21.4 13.1 32.9 104.5 62.8 9.5 17.9 61.8 23.4 37.6 27.6 47.3 23.3 39.8 113.5 80.8 19.7 58.8 81.5 11.6 15.8 37.0 22.9 45.0 37.5 46.7 35.8 37.9 AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.1;lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.5;Erythroid cells: 59.3;Extravillous trophoblasts: 89.1;Granulosa cells: 24.7;Hofbauer cells: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cell line specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "CAB005862, HPA037708" Enhanced Enhanced Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Midbody "CAB005862: AB_449204, HPA037708: AB_2675623" "unprognostic (4.76e-2)" "unprognostic (3.61e-3)" "unprognostic (2.25e-1)" "unprognostic (3.14e-2)" "unprognostic (2.27e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (1.99e-3)" "unprognostic (9.41e-3)" "unprognostic (3.47e-2)" "unprognostic (4.61e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.77e-2)" "unprognostic (2.93e-1)" "unprognostic (6.76e-2)" "unprognostic (3.77e-1)" 1.1 1.2 0.1 14.2 0.2 44.1 1.7 0.2 0.2 3.0 0.1 11.1 12.1 1.6 0.4 18.6 0.6 1.5 0.7 0.1 0.2 0.9 2.0 2.5 36.7 0.1 0.3 0.5 0.6 0.3 0.2 8.2 0.3 0.8 11.0 0.0 2.7 0.3 5.5 9.3 11.6 3.2 0.0 12.0 4.6 1.2 0.4 60.1 0.6 0.0 36.6 3.5 5.9 0.2 196.5 130.9 191.1 93.0 4.2 6.5 73.4 91.7 49.5 186.2 170.6 171.5 57.4 193.3 46.2 37.0 77.0 139.8 140.1 62.6 153.7 84.9 231.3 115.7 78.3 146.1 0.7 62.2 109.2 3.5 2.9 109.4 67.7 18.5 86.5 123.6 73.3 73.4 82.9 92.9 225.1 87.4 119.6 63.9 57.6 149.8 176.1 80.5 41.2 38.2 41.2 59.1 81.7 36.5 61.2 56.5 63.5 41.4 33.9 74.3 75.6 67.6 243.3 53.2 37.7 147.9 35.7 92.9 153.4 0.0 0.4 0.6 0.5 0.3 0.1 1.1 1.3 2.1 0.5 2.5 0.1 0.7 0.9 0.3 0.2 0.2 7.9 0.9 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.4 0.2 0.3 0.0 0.5 0.0 7.6 4.5 1.8 6.1 0.6 0.0 1.8 2.2 1.4 0.0 2.6 0.0 0.0 40.5 1.8 13.2 0.0 0.4 0.1 0.5 1.6 3.1 0.0 59.3 0.0 0.0 89.1 5.7 6.1 2.1 4.5 24.7 6.1 0.7 29.4 0.0 0.0 10.8 0.0 5.7 7.3 0.2 0.6 5.1 1.8 0.0 0.9 0.0 3.1 0.0 0.1 0.3 2.8 0.0 15.4 1.2 1.5 0.1 0.2 0.0 0.0 0.1 4.8 1.6 7.2 11.8 2.4 9.0 4.3 1.0 22.0 2.8 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 B3GNT9 MGC4655 ENSG00000237172 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9" Q6UX72 16 67148104-67150998 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 12.9;Leydig cells: 11.5;Peritubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SiHa: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052743, HPA062734" Approved Approved "Nucleoli fibrillar center,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoli fibrillar center" "HPA052743: AB_2681934, HPA062734: AB_2684854" "unprognostic (2.56e-2)" "unprognostic (2.22e-1)" "unprognostic (2.34e-2)" "unprognostic (1.07e-1)" "unprognostic (6.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.28e-2)" "unprognostic (3.01e-2)" "unprognostic (1.89e-1)" "unprognostic (1.96e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (4.96e-3)" "unprognostic (7.56e-3)" 7.7 8.4 7.1 4.2 8.0 0.2 5.7 7.5 6.8 15.0 8.4 7.6 3.2 13.4 7.3 5.2 13.7 6.8 13.8 7.1 8.0 7.4 2.5 9.0 2.9 8.7 9.7 15.0 3.5 21.8 20.5 7.9 8.7 11.8 3.3 1.4 9.0 14.8 1.9 5.9 5.6 7.8 9.3 5.6 6.1 6.0 7.7 1.5 18.7 2.1 2.5 11.7 8.9 11.1 4.9 8.8 0.7 0.9 27.7 28.6 1.0 22.5 36.2 14.4 18.5 4.0 0.8 0.6 1.5 34.9 6.0 11.1 0.3 1.0 7.8 7.6 3.2 0.7 9.7 3.5 22.3 0.6 0.5 23.7 8.3 14.0 0.4 35.8 2.0 0.5 1.0 2.7 22.6 2.6 2.6 1.2 5.4 3.8 7.7 7.4 12.9 4.4 2.3 6.0 5.0 11.2 50.9 0.2 0.8 4.3 1.3 3.9 4.6 25.6 1.1 25.9 10.2 3.2 2.4 0.8 31.9 1.3 12.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 7.1 8.0 7.5 6.8 7.1 8.0 8.7 9.7 8.7 9.3 7.7 11.1 1.2 6.4 5.0 1.0 1.2 3.2 2.8 2.4 9.6 1.6 3.2 2.3 2.6 5.7 2.4 3.7 0.0 0.3 0.1 0.4 0.0 1.3 5.3 2.5 7.6 2.0 2.4 0.0 0.4 1.7 0.5 12.9 2.6 2.2 0.0 3.0 6.4 0.1 1.8 0.0 1.3 0.9 2.0 0.6 3.3 6.9 11.5 0.4 1.8 0.0 0.1 0.9 0.0 1.0 2.3 0.9 0.1 13.5 4.7 2.4 0.1 0.9 4.2 0.3 6.6 3.2 6.6 4.4 2.8 2.7 4.1 0.8 1.5 2.9 0.8 1.3 BCAP29 "BAP29, DKFZp686M2086" ENSG00000075790 "B cell receptor associated protein 29" Q9UHQ4 7 107580246-107629170 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029215, HPA049694" Supported Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA029215: AB_10602331, HPA049694: AB_2680854" "unprognostic (3.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.82e-2)" "unprognostic (1.05e-2)" "unprognostic (5.42e-3)" "unprognostic (4.71e-3)" "prognostic unfavorable (3.62e-4)" "unprognostic (6.43e-2)" "unprognostic (7.22e-2)" "unprognostic (9.64e-2)" "unprognostic (2.31e-2)" "unprognostic (7.36e-2)" "unprognostic (8.34e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-2)" "unprognostic (5.28e-3)" "unprognostic (1.81e-1)" 47.1 25.7 19.4 22.5 23.7 16.7 28.0 18.1 27.0 48.6 12.8 32.6 16.1 42.6 18.6 34.4 21.7 23.0 61.0 24.4 17.9 20.1 33.3 26.0 16.7 17.5 17.6 21.4 18.9 34.5 12.2 26.7 18.0 31.9 31.2 9.6 18.4 25.0 38.7 22.1 18.8 38.2 19.5 18.1 22.4 70.1 19.2 12.8 85.5 31.5 15.7 30.9 32.5 21.1 71.7 22.8 26.4 13.8 65.2 81.6 22.6 80.6 68.2 32.9 39.7 23.2 72.1 13.4 54.5 58.1 75.1 35.8 13.7 38.6 52.5 50.1 17.3 27.1 35.6 26.2 63.3 33.6 41.2 48.9 31.8 46.7 38.0 95.4 116.9 25.3 58.3 33.4 75.4 67.2 23.2 34.3 15.4 29.7 30.0 18.6 34.1 34.6 60.6 49.1 10.2 37.7 68.2 54.9 58.2 39.3 25.6 37.5 113.9 102.5 52.1 94.6 104.7 31.7 67.9 27.5 66.5 30.5 77.2 47.5 10.5 25.5 9.5 13.6 9.3 12.8 7.5 9.5 10.0 8.5 4.3 8.5 3.9 9.9 21.7 10.1 13.6 8.1 19.4 23.7 18.1 27.0 24.4 17.9 17.5 17.6 18.0 19.5 19.2 21.1 169.8 67.3 57.2 35.6 33.9 38.5 80.7 99.0 25.0 35.2 40.4 34.2 117.8 27.1 77.7 23.9 10.4 30.2 31.4 38.1 15.6 46.4 227.1 54.6 93.3 99.0 22.3 73.2 81.1 73.6 50.8 72.9 32.6 102.0 58.3 14.8 73.2 40.7 52.6 8.4 71.3 35.8 69.2 36.6 35.6 95.8 61.2 49.6 37.4 44.0 41.6 28.3 22.6 50.8 49.7 71.2 32.5 89.1 17.7 110.4 15.6 19.5 55.9 26.7 78.9 62.9 91.3 202.2 35.0 46.5 38.8 70.7 33.5 32.0 45.4 83.5 BCAP31 "6C6-Ag, BAP31, CDM, DXS1357E" ENSG00000185825 "B cell receptor associated protein 31" P51572 X 153700492-153724565 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Deafness, Dystonia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003906, CAB015350, CAB015424" Supported Approved Enhanced "Endoplasmic reticulum" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB015350: AB_2243544, CAB015424: AB_781567, HPA003906: AB_1078270" "unprognostic (1.02e-2)" "unprognostic (2.14e-2)" "unprognostic (1.19e-2)" "unprognostic (3.70e-1)" "unprognostic (2.36e-2)" "prognostic unfavorable (9.87e-4)" "unprognostic (3.25e-3)" "unprognostic (4.20e-2)" "unprognostic (1.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (2.11e-1)" "unprognostic (1.28e-2)" "unprognostic (8.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" 294.1 213.9 171.5 100.9 175.5 151.3 210.9 171.8 213.9 139.5 202.5 157.7 133.3 127.4 228.9 214.0 151.0 118.0 123.5 183.0 192.1 160.7 185.5 144.5 111.8 190.8 187.5 130.9 266.4 193.7 123.5 143.3 195.3 154.6 166.5 63.9 179.7 177.7 81.9 187.3 143.8 155.0 183.4 138.5 129.3 117.3 186.9 99.7 161.4 75.5 134.6 177.9 145.8 185.0 505.5 482.4 128.0 650.6 593.8 179.1 295.3 269.9 287.5 291.6 371.6 386.8 361.9 315.9 1068.1 412.2 373.9 506.8 337.3 518.6 221.0 152.8 436.9 198.4 350.4 323.3 276.4 335.1 373.2 233.8 454.2 282.3 330.1 298.4 372.6 172.0 268.0 528.3 332.7 535.3 187.3 402.5 145.8 704.6 431.7 207.5 152.8 693.2 459.3 546.8 173.3 241.8 111.8 520.6 350.0 200.3 196.2 320.2 380.0 248.9 234.7 338.9 495.1 518.0 1120.1 397.3 460.9 402.6 223.7 630.5 484.2 489.1 507.5 535.7 454.7 436.1 504.5 507.4 420.7 463.6 439.1 474.7 624.5 449.8 632.3 666.9 457.1 1110.8 171.5 175.5 171.8 213.9 183.0 192.1 190.8 187.5 195.3 183.4 186.9 185.0 184.9 112.2 114.1 14.7 97.5 141.9 232.2 374.0 172.4 53.0 127.3 165.7 60.3 134.4 222.8 128.8 45.9 467.5 113.5 194.1 37.2 252.4 7.8 99.7 70.1 165.5 103.2 59.3 16.9 210.0 444.8 103.6 78.5 103.9 95.6 68.5 199.6 216.0 356.2 32.0 12.8 155.1 244.1 148.4 125.6 20.6 105.3 166.2 160.1 17.8 137.5 138.2 111.2 11.6 12.9 247.1 187.4 98.9 120.8 191.8 242.8 170.9 172.6 51.8 157.8 42.9 106.5 310.3 231.3 174.0 130.4 538.1 114.6 120.4 187.0 260.4 BCAS2 "DAM1, Snt309, SPF27" ENSG00000116752 "BCAS2 pre-mRNA processing factor" O75934 1 114567557-114581629 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 613.4" "Low region specificity" "Detected in all" HPA067881 Supported Supported "Nuclear speckles,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Centrosome" "HPA067881: AB_2685915" "unprognostic (6.93e-2)" "unprognostic (1.88e-2)" "unprognostic (8.58e-3)" "unprognostic (4.74e-2)" "unprognostic (2.49e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (8.23e-7)" "unprognostic (1.16e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.96e-4)" "unprognostic (1.57e-2)" "prognostic unfavorable (4.27e-4)" "prognostic favorable (6.49e-4)" "unprognostic (2.25e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.24e-4)" "unprognostic (1.87e-1)" 31.9 40.6 32.8 28.0 35.4 76.2 38.2 36.7 45.3 27.1 34.6 31.6 25.5 35.1 49.7 34.1 24.9 31.8 39.3 35.7 38.8 44.6 51.3 26.9 38.5 34.9 37.6 32.5 28.8 41.3 33.1 27.8 37.8 35.6 32.1 40.4 29.6 27.2 56.4 29.8 26.1 27.8 34.7 26.1 28.7 31.8 34.6 32.2 42.4 25.9 36.2 41.5 23.4 37.7 100.0 35.6 70.8 69.9 37.8 43.8 108.8 71.3 57.0 95.6 97.4 50.8 40.6 88.8 93.9 46.9 64.3 47.8 85.5 72.7 133.3 76.7 75.7 45.0 67.2 74.6 68.8 117.8 48.1 39.2 79.4 97.5 121.3 44.2 63.7 95.0 89.6 64.5 80.5 613.4 103.1 87.5 125.6 60.8 80.8 73.9 127.6 62.2 68.1 85.9 93.5 62.2 90.3 70.3 114.3 59.6 62.3 91.0 52.8 58.2 74.7 116.9 138.2 68.5 76.9 143.4 113.4 94.7 223.9 54.4 36.8 65.3 56.0 45.2 78.9 63.3 71.6 70.6 39.7 58.0 73.8 71.9 34.7 75.0 51.0 51.2 77.6 72.8 32.8 35.4 36.7 45.3 35.7 38.8 34.9 37.6 37.8 34.7 34.6 37.7 51.6 28.9 45.4 11.1 110.1 77.9 114.2 155.9 91.0 62.6 36.7 49.1 76.0 27.1 85.4 49.7 37.5 76.6 99.0 26.4 95.9 66.6 30.3 79.0 51.5 46.9 50.0 30.5 16.4 66.8 89.8 60.0 25.0 139.1 99.1 46.0 28.2 31.3 66.9 38.7 15.1 43.1 103.7 34.9 93.3 17.7 39.7 80.8 67.6 12.2 50.6 98.3 55.6 15.1 18.1 51.2 37.9 43.6 176.7 49.8 29.4 103.9 55.6 67.1 39.5 55.5 71.4 80.8 40.6 95.7 63.4 101.2 117.4 64.2 36.0 114.2 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 160.0;Pancreatic endocrine cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB072801: , HPA035734: AB_2674757" "unprognostic (2.29e-1)" "unprognostic (5.40e-3)" "unprognostic (1.78e-2)" "prognostic unfavorable (9.10e-4)" "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (5.04e-2)" "unprognostic (7.82e-3)" "prognostic favorable (9.57e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (1.06e-1)" "prognostic favorable (8.89e-5)" "unprognostic (9.67e-2)" "unprognostic (3.03e-2)" "unprognostic (2.02e-2)" "unprognostic (3.32e-2)" 80.3 46.9 46.3 26.1 53.7 99.0 71.0 46.7 54.5 46.5 88.2 42.4 49.4 39.2 11.9 77.8 42.7 51.7 77.9 42.2 48.2 95.7 85.2 95.1 25.8 49.5 49.4 23.1 54.7 30.4 49.8 42.0 51.1 52.0 26.2 41.0 70.6 25.2 55.4 65.7 48.9 25.0 41.3 53.4 66.6 46.2 54.4 111.5 51.4 38.8 28.9 42.8 54.7 59.7 327.0 188.4 30.7 32.4 167.8 123.1 101.0 73.8 113.2 69.6 66.4 429.2 150.9 48.2 176.7 108.4 140.7 105.8 42.9 216.7 46.2 55.1 8.6 231.3 34.4 231.6 123.0 19.6 137.7 90.7 77.4 89.4 194.0 102.4 106.0 81.6 150.0 34.5 238.7 94.3 73.9 20.6 45.4 150.8 153.2 43.5 92.9 164.3 249.3 83.4 85.4 38.4 89.3 92.6 42.4 57.2 180.5 26.3 154.1 90.0 109.1 36.8 139.4 22.7 150.7 37.9 143.5 99.5 59.5 28.6 11.0 25.6 39.9 11.7 30.9 4.8 17.1 26.8 10.4 6.0 7.7 18.6 12.5 19.8 13.4 7.0 21.8 28.2 46.3 53.7 46.7 54.5 42.2 48.2 49.5 49.4 51.1 41.3 54.4 59.7 41.6 16.0 9.2 22.5 10.1 18.4 70.2 40.8 26.7 21.9 25.5 15.4 9.7 91.5 36.3 38.6 45.9 27.1 13.7 41.7 86.1 92.2 10.2 71.4 14.6 35.8 24.7 160.0 21.8 65.9 11.3 15.5 37.2 58.2 12.7 10.6 36.4 40.8 38.2 28.6 19.5 26.0 69.2 22.1 13.3 4.6 19.0 27.6 17.8 49.6 76.9 24.1 54.6 13.6 55.6 187.7 22.4 42.9 38.0 102.9 54.6 76.5 76.4 33.7 46.0 14.9 42.7 31.0 15.1 13.6 9.8 18.9 24.9 13.6 19.6 143.0 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 194.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 418.7;Muller glia cells: 285.9;Proximal tubular cells: 201.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.7;NK-cells: 62.0;T-cells: 68.6" "Cell line enhanced" "Detected in many" "hTCEpi: 94.7;NTERA-2: 91.4;SCLC-21H: 135.2;SH-SY5Y: 61.4" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA045384: AB_2679305, HPA078630: " "unprognostic (7.56e-2)" "unprognostic (7.08e-2)" "unprognostic (3.46e-2)" "prognostic unfavorable (8.54e-7)" "unprognostic (3.21e-1)" "unprognostic (1.65e-1)" "unprognostic (4.27e-2)" "prognostic favorable (1.52e-4)" "unprognostic (7.36e-3)" "unprognostic (6.82e-2)" "unprognostic (8.22e-3)" "unprognostic (6.63e-2)" "prognostic favorable (3.05e-13)" "unprognostic (4.14e-3)" "unprognostic (6.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" 5.8 73.6 133.5 6.8 134.9 13.7 19.4 119.0 167.3 16.4 98.2 10.2 3.4 27.6 123.8 9.9 15.5 7.6 29.5 134.4 153.2 58.7 2.5 12.7 14.2 120.7 125.6 62.8 35.5 123.1 194.6 8.0 123.7 24.2 6.0 83.5 26.7 21.0 9.1 17.1 14.0 8.7 117.7 18.5 16.7 43.1 138.6 21.0 103.3 11.5 16.9 8.7 10.7 132.2 0.0 2.8 11.3 0.1 0.2 0.0 45.5 0.3 6.1 7.7 11.3 8.4 3.8 0.0 31.6 0.0 55.4 2.0 0.1 9.4 6.6 0.1 25.4 1.4 1.4 0.4 46.0 0.1 25.4 2.8 94.7 3.7 29.1 17.8 0.5 33.6 17.4 0.7 1.0 4.2 20.1 0.2 91.4 0.0 8.4 0.1 0.0 0.2 3.8 3.7 135.2 61.4 5.9 1.4 22.2 10.7 11.2 0.1 0.0 0.1 9.0 0.3 2.1 30.8 21.6 0.1 15.3 0.0 1.3 13.4 0.4 1.1 21.8 0.4 31.0 52.7 43.8 25.7 1.6 42.3 68.6 50.0 1.4 62.0 0.1 10.0 33.7 18.4 133.5 134.9 119.0 167.3 134.4 153.2 120.7 125.6 123.7 117.7 138.6 132.2 3.7 16.0 68.5 15.0 41.6 31.6 95.6 17.4 100.7 184.7 65.8 145.5 27.0 60.1 43.4 114.0 43.8 72.2 20.9 5.0 418.7 47.5 17.9 11.6 3.3 13.7 100.5 9.4 56.7 42.7 19.9 13.1 23.0 17.0 12.7 87.6 3.6 0.9 7.0 121.1 53.0 29.6 16.2 0.3 5.3 69.4 15.8 4.6 26.6 7.5 2.5 285.9 27.8 35.2 25.8 19.8 8.4 22.2 16.5 64.5 3.7 201.3 9.0 120.5 6.6 32.0 11.4 16.8 5.8 25.7 26.7 63.8 30.2 22.3 22.3 51.1 BEX4 "BEXL1, FLJ10097" ENSG00000102409 "Brain expressed X-linked 4" Q9NWD9 X 103215108-103217246 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 309.3;Syncytiotrophoblasts: 364.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 162.5;HMC-1: 188.1;K-562: 232.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045105, HPA051935" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Cytosol" "HPA045105: AB_10966792, HPA051935: AB_2681667" "unprognostic (1.45e-1)" "unprognostic (2.12e-1)" "unprognostic (1.01e-2)" "unprognostic (2.55e-3)" "unprognostic (1.75e-3)" "unprognostic (3.69e-1)" "unprognostic (1.52e-1)" "unprognostic (1.06e-3)" "unprognostic (3.03e-1)" "unprognostic (6.33e-2)" "prognostic favorable (9.41e-4)" "unprognostic (1.62e-2)" "prognostic favorable (2.54e-14)" "unprognostic (1.62e-3)" "unprognostic (2.60e-2)" "unprognostic (1.13e-1)" "unprognostic (5.33e-2)" 32.2 99.9 186.5 24.8 187.5 71.4 56.3 173.4 225.0 53.0 154.9 63.6 17.0 70.3 265.9 48.0 65.7 40.2 101.9 188.8 209.2 97.6 13.5 44.0 32.9 185.7 185.7 102.6 34.7 126.0 134.0 60.6 184.6 80.2 26.4 92.0 74.6 83.1 6.8 26.6 32.2 56.4 183.7 68.7 36.2 46.1 195.1 57.0 131.1 13.6 34.8 46.6 44.3 188.2 0.0 0.2 96.4 0.0 24.1 16.6 86.5 23.2 19.8 42.6 77.7 0.0 1.4 0.3 38.1 16.2 36.0 0.7 39.1 5.3 46.8 0.1 36.8 162.5 0.0 0.1 73.7 123.0 188.1 62.3 12.9 22.3 0.0 47.3 50.2 62.2 232.5 0.5 13.1 0.5 86.4 1.0 117.0 0.0 6.9 0.2 28.0 0.6 39.1 2.4 71.7 109.3 8.1 1.5 5.1 93.0 3.9 1.3 1.3 5.5 34.3 0.8 0.3 12.5 6.0 0.2 16.0 0.0 4.9 118.6 23.1 42.3 31.6 30.0 26.5 37.6 38.2 32.0 51.3 33.7 65.5 52.2 5.2 100.5 26.4 79.0 40.3 43.9 186.5 187.5 173.4 225.0 188.8 209.2 185.7 185.7 184.6 183.7 195.1 188.2 45.7 35.3 40.4 25.5 38.7 27.3 133.8 86.0 87.0 174.9 99.0 105.4 81.3 81.5 64.0 99.3 25.0 309.3 47.5 6.8 299.3 66.4 4.7 31.2 35.5 59.2 63.1 35.1 70.0 13.7 156.0 65.1 19.4 38.1 109.2 147.8 73.2 0.7 88.3 222.1 69.6 37.2 52.9 55.5 53.2 12.9 63.3 68.9 115.6 22.5 118.4 217.8 34.0 34.2 64.3 10.8 23.3 61.3 22.2 118.1 8.1 186.5 33.2 81.0 52.6 64.4 57.4 27.4 14.3 42.5 24.2 364.3 37.2 115.0 28.7 111.7 BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9;lymphoid tissue: 41.0;testis: 19.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.7;Early spermatids: 94.1;Erythroid cells: 166.7;Extravillous trophoblasts: 162.0;Spermatocytes: 191.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Cytokinetic bridge" "CAB004270: AB_628302, HPA002830: AB_1857672" "unprognostic (8.04e-2)" "unprognostic (3.51e-2)" "unprognostic (4.48e-3)" "unprognostic (2.72e-3)" "unprognostic (3.37e-1)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.28e-6)" "prognostic unfavorable (4.49e-4)" "unprognostic (3.56e-3)" "unprognostic (4.53e-3)" "unprognostic (2.87e-3)" "unprognostic (6.67e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.77e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.16e-1)" 0.9 1.1 0.3 8.5 0.5 37.9 5.1 0.6 0.6 1.9 0.4 6.7 7.9 1.6 0.0 12.8 0.6 1.1 0.5 0.4 0.4 0.7 2.1 1.9 16.2 0.6 0.6 0.4 0.6 0.2 0.2 6.1 0.5 0.6 8.0 0.1 1.8 0.2 1.1 5.8 7.6 4.3 0.4 5.8 3.7 19.6 1.0 41.0 0.4 0.1 16.3 2.6 3.2 0.8 139.1 126.2 111.3 121.5 6.7 11.3 41.0 103.6 57.5 144.0 94.2 104.0 52.9 140.7 41.5 60.5 108.7 71.9 113.6 66.6 125.2 48.2 157.5 93.2 71.4 123.1 0.8 90.8 67.0 3.9 4.5 79.8 59.2 21.0 103.5 104.3 118.8 116.0 112.6 79.7 195.5 86.2 83.4 96.3 218.0 100.5 180.2 108.4 34.5 50.2 136.8 94.8 80.3 88.6 71.7 54.1 117.5 84.8 39.5 173.1 152.6 76.0 150.4 83.3 72.2 163.3 63.3 37.8 154.4 0.0 0.0 0.0 0.7 0.0 0.1 2.4 4.1 2.8 0.8 0.2 0.0 0.4 0.5 2.4 0.0 0.2 14.1 3.1 0.3 0.5 0.6 0.6 0.4 0.4 0.6 0.6 0.5 0.4 1.0 0.8 1.2 0.0 20.0 0.0 15.9 8.2 3.7 12.2 2.8 0.7 7.7 8.6 2.3 2.8 10.8 0.0 0.0 74.7 3.3 10.7 0.0 2.0 94.1 5.4 5.1 8.8 3.0 166.7 0.4 0.0 162.0 15.1 8.6 6.9 9.5 42.7 12.8 2.7 52.1 0.0 0.2 17.1 10.2 13.7 13.8 68.4 3.1 9.6 1.8 0.0 0.6 0.4 7.2 0.0 0.3 0.4 2.5 0.7 50.2 2.8 3.2 0.1 2.6 0.5 6.6 0.9 15.2 191.1 58.2 31.3 6.5 19.2 10.1 3.4 38.8 6.3 BORCS7 "C10orf32, FLJ40752" ENSG00000166275 "BLOC-1 related complex subunit 7" Q96B45 10 102854259-102864961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Proximal tubular cells: 208.5;Theca cells: 209.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037648 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" Cytosol "HPA037648: AB_10673634" "unprognostic (2.16e-1)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (2.05e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-3)" "unprognostic (3.55e-2)" "unprognostic (1.35e-2)" "unprognostic (7.46e-3)" "unprognostic (3.16e-2)" "unprognostic (1.77e-1)" "prognostic favorable (9.08e-8)" "unprognostic (9.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.06e-1)" "unprognostic (1.67e-3)" 25.4 58.5 20.5 12.8 20.9 23.4 29.8 20.3 25.1 21.3 22.3 19.7 23.2 21.8 23.7 13.4 29.7 22.4 22.3 21.5 23.1 39.8 67.0 23.8 15.1 21.2 21.7 21.8 17.5 53.3 23.7 21.7 21.3 27.2 15.2 20.2 16.9 17.4 28.6 13.9 19.5 16.7 22.5 24.4 20.9 20.2 22.7 14.6 55.3 25.9 12.3 17.4 16.0 23.0 14.9 19.8 23.4 20.7 25.6 35.1 19.5 21.6 44.1 16.3 15.5 13.3 16.6 9.4 11.1 34.6 17.1 12.2 7.9 11.1 12.0 12.1 16.7 21.7 12.5 27.7 29.5 39.4 35.9 44.1 29.8 11.0 17.4 34.0 28.9 13.2 13.0 9.7 26.4 10.9 11.0 16.2 7.9 20.3 18.4 19.8 31.4 13.8 13.6 16.1 6.6 25.5 8.0 14.2 34.7 10.4 27.0 22.2 21.6 13.7 14.6 14.1 15.3 24.9 40.8 11.1 29.0 22.7 5.0 31.3 30.1 22.9 17.3 35.0 19.4 26.5 17.9 18.0 22.1 23.2 19.8 18.4 9.6 27.7 32.9 47.1 19.7 15.1 20.5 20.9 20.3 25.1 21.5 23.1 21.2 21.7 21.3 22.5 22.7 23.0 85.2 54.5 79.6 0.0 49.1 0.0 61.0 0.0 45.5 50.9 94.5 62.9 0.0 48.6 32.2 42.3 39.6 89.6 57.4 18.0 201.5 35.3 21.1 61.1 38.8 67.3 34.0 18.3 0.0 33.3 39.2 60.4 39.8 31.9 34.1 44.2 68.2 74.9 51.7 63.9 0.0 33.4 0.0 49.8 0.0 22.8 42.3 54.1 0.0 0.0 52.1 109.8 53.5 0.0 0.0 28.5 48.5 62.1 28.6 53.8 70.1 208.5 43.7 50.6 39.5 53.3 44.0 80.1 52.4 44.7 0.0 121.5 39.8 209.5 41.0 54.5 BRCA1 "BRCC1, FANCS, PPP1R53, RNF53" ENSG00000012048 "BRCA1 DNA repair associated" P38398 17 43044295-43170245 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 42.5;Granulosa cells: 38.2;Spermatocytes: 105.8;Spermatogonia: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 6.8;classical monocyte: 14.7;intermediate monocyte: 4.7;myeloid DC: 10.9;neutrophil: 11.3" "Group enriched" "Detected in all" 6 "dendritic cells: 10.9;granulocytes: 11.3;monocytes: 14.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB001946, HPA004840, HPA034966, HPA057371" Approved Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nuclear bodies" "CAB001946: , HPA004840: , HPA034966: AB_10795287, HPA057371: AB_2732611" "unprognostic (7.87e-3)" "unprognostic (6.97e-2)" "unprognostic (3.53e-3)" "unprognostic (2.39e-1)" "unprognostic (5.42e-2)" "unprognostic (7.07e-3)" "unprognostic (1.56e-3)" "unprognostic (4.14e-3)" "unprognostic (9.62e-3)" "unprognostic (2.47e-1)" "unprognostic (5.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.08e-4)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.31e-2)" 3.1 1.8 4.2 7.5 7.2 13.0 3.6 4.7 5.2 2.7 2.7 6.8 3.2 3.1 2.2 4.0 3.7 1.9 3.0 3.6 4.1 2.0 5.6 3.2 10.3 5.6 5.0 2.8 2.8 5.9 2.8 3.8 6.0 2.4 7.4 8.2 3.2 1.6 4.2 6.0 5.1 3.9 3.7 3.9 3.6 13.0 5.5 14.5 7.8 3.7 11.2 2.8 2.4 10.8 44.1 69.1 37.8 30.1 6.0 13.4 36.6 50.6 21.5 41.9 39.3 42.3 33.4 100.8 9.1 19.0 49.0 49.5 51.9 28.3 69.5 46.9 38.0 48.1 54.0 37.1 1.3 86.0 39.9 3.8 4.5 63.1 20.0 10.6 22.3 46.6 73.7 42.2 39.7 30.0 72.0 27.8 20.5 29.1 18.7 49.0 79.8 40.8 15.4 42.1 25.8 27.4 38.8 12.5 19.4 25.5 33.9 39.6 13.8 37.2 29.6 49.0 53.2 20.1 51.2 75.5 29.6 49.6 39.4 6.8 14.7 2.2 1.5 4.7 1.5 1.2 1.5 1.2 10.9 2.1 1.3 1.5 11.3 1.5 2.0 1.7 0.5 17.5 4.2 7.2 4.7 5.2 3.6 4.1 5.6 5.0 6.0 3.7 5.5 10.8 5.0 0.0 2.8 9.4 5.8 2.9 4.5 1.9 1.2 10.3 4.4 5.2 10.1 5.7 3.5 1.8 22.9 12.8 8.1 6.2 0.0 3.0 11.9 14.0 6.3 4.7 0.0 42.5 3.0 1.1 18.2 7.4 6.1 4.2 8.2 38.2 5.3 18.3 10.1 11.8 4.4 7.5 0.0 3.9 2.8 8.0 2.5 6.4 0.0 4.7 4.9 2.4 5.2 3.0 18.7 1.7 2.4 1.5 16.6 2.3 1.1 1.0 10.0 22.8 6.6 13.7 5.5 105.8 73.5 8.2 2.3 4.0 4.7 9.7 12.7 3.4 BRCC3 "BRCC36, C6.1A, CXorf53" ENSG00000185515 "BRCA1/BRCA2-containing complex subunit 3" P46736 X 155071420-155123077 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Metalloprotease, Protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048737 Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA048737: AB_2680504" "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "unprognostic (5.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (2.88e-2)" "unprognostic (4.48e-2)" "unprognostic (6.47e-3)" "unprognostic (1.33e-1)" "unprognostic (9.68e-2)" "unprognostic (1.35e-3)" "unprognostic (3.72e-2)" "unprognostic (3.71e-3)" "unprognostic (7.14e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" 9.9 12.9 6.8 12.1 6.6 15.6 15.8 9.2 7.7 12.8 6.8 22.3 19.3 9.2 18.5 18.4 11.6 8.4 11.2 6.6 7.0 17.8 13.8 9.8 15.4 5.9 7.1 8.1 11.4 14.7 5.2 14.0 6.7 14.6 23.3 12.9 18.5 10.9 17.8 11.1 16.9 10.6 5.4 11.0 15.6 2.3 7.4 13.4 15.2 17.6 15.5 12.6 6.3 6.6 95.6 45.1 24.4 19.6 20.9 17.7 37.9 35.9 25.8 24.1 52.3 44.0 40.1 84.1 62.8 22.1 36.1 36.3 54.4 33.6 38.0 45.4 42.1 17.7 76.1 41.4 15.8 62.8 25.5 17.3 16.9 35.1 28.5 23.1 30.1 32.2 27.4 24.9 24.6 33.6 25.8 28.8 22.3 101.9 41.9 36.2 43.3 42.0 36.8 36.5 38.0 17.3 25.6 43.6 27.3 31.5 25.2 33.7 31.5 20.4 32.1 27.6 53.8 30.0 56.1 114.5 28.2 61.5 25.3 36.8 18.8 34.0 20.0 22.9 23.4 17.6 19.3 18.2 21.2 16.7 14.8 16.6 10.5 28.4 24.1 13.3 25.4 16.9 6.8 6.6 9.2 7.7 6.6 7.0 5.9 7.1 6.7 5.4 7.4 6.6 12.0 32.1 23.3 16.6 14.0 5.5 7.0 13.8 6.8 13.0 15.0 14.0 27.2 10.0 28.5 7.3 14.6 26.7 17.6 25.5 19.6 22.9 0.6 13.8 13.7 10.6 9.6 17.1 31.9 19.8 26.6 11.3 12.8 15.9 26.6 13.7 8.6 8.6 17.4 8.4 35.2 22.6 16.2 9.5 7.0 1.3 5.9 14.5 5.4 15.9 22.3 12.9 20.6 26.7 29.2 14.7 16.8 12.0 21.1 10.3 16.3 18.0 25.1 14.5 19.7 12.6 22.9 1.2 1.3 26.2 6.5 13.5 14.9 18.3 27.3 8.3 BRD2 "BRD2-IT1, D6S113E, FSRG1, KIAA9001, NAT, RING3" ENSG00000204256 "Bromodomain containing 2" P25440 6 32968594-32981505 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042816 Approved Enhanced "Nuclear speckles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA042816: AB_10794766" "unprognostic (2.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.45e-1)" "unprognostic (9.89e-2)" "unprognostic (5.03e-2)" "unprognostic (2.54e-1)" "unprognostic (6.85e-3)" "unprognostic (1.39e-2)" "unprognostic (1.95e-2)" "unprognostic (3.42e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "unprognostic (1.44e-2)" 64.2 61.8 0.8 22.1 2.1 66.5 62.4 4.7 3.8 67.7 0.2 62.1 19.8 71.3 1.8 67.9 66.6 17.4 51.7 3.0 2.8 68.3 61.9 65.3 22.1 1.5 2.4 81.7 80.4 26.3 71.4 19.4 2.1 60.8 11.6 10.1 66.1 18.2 71.4 69.5 60.8 11.7 1.4 71.2 66.0 82.9 2.3 26.9 77.0 10.4 21.2 61.6 65.0 4.0 45.7 19.5 41.6 41.8 31.8 28.5 38.3 44.6 44.4 48.5 35.8 22.7 22.5 37.3 44.6 37.2 32.4 28.1 39.3 33.2 27.7 49.5 147.7 41.2 18.3 14.6 23.5 60.6 39.2 29.2 28.7 38.2 44.9 27.6 21.3 35.2 44.4 76.0 21.7 12.1 77.0 8.5 24.0 28.9 20.4 76.2 18.7 53.8 13.8 26.6 85.6 28.9 54.5 63.7 52.7 27.8 37.4 39.0 27.5 58.6 32.0 21.5 50.0 61.1 69.5 77.9 23.1 19.7 47.8 9.6 7.6 11.6 14.5 8.8 13.0 9.2 9.4 9.9 10.6 8.7 6.6 10.4 9.7 10.3 9.5 8.5 13.3 11.7 0.8 2.1 4.7 3.8 3.0 2.8 1.5 2.4 2.1 1.4 2.3 4.0 325.8 76.9 121.5 38.2 327.1 212.1 232.7 70.0 478.1 78.6 295.5 383.9 171.7 94.4 80.1 60.7 104.3 91.7 395.7 210.7 21.5 69.2 302.4 201.9 149.3 191.2 259.1 97.6 16.1 91.4 145.0 224.2 249.8 256.6 115.2 103.1 113.2 85.3 79.9 55.5 19.9 247.5 77.3 92.6 209.2 177.9 86.9 194.5 124.5 26.2 94.7 62.8 107.1 15.1 22.1 81.2 137.3 77.1 313.0 211.5 133.7 39.5 84.4 65.1 39.5 240.0 251.3 88.4 137.9 365.0 226.9 205.1 356.7 71.2 179.5 248.4 BRD3OS "bA374P20.3, FLJ35348, LINC00094, NCRNA00094" ENSG00000235106 "BRD3 opposite strand" A0A1B0GUI7 9 134025481-134034666 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Collecting duct cells: 16.5;Distal tubular cells: 19.6;Endometrial ciliated cells: 18.3;Endometrial stromal cells: 11.9;Proximal tubular cells: 15.5;Respiratory ciliated cells: 21.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (7.26e-2)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-1)" "unprognostic (3.02e-1)" "unprognostic (3.87e-2)" "unprognostic (1.62e-1)" "unprognostic (1.83e-1)" "unprognostic (2.66e-1)" "unprognostic (1.83e-1)" "unprognostic (7.12e-3)" "unprognostic (1.97e-1)" "prognostic favorable (4.24e-5)" "unprognostic (1.95e-1)" "unprognostic (5.25e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.31e-4)" 8.0 13.9 29.4 5.3 30.6 2.0 7.8 23.6 32.1 12.5 26.0 11.8 3.0 12.0 11.5 6.1 22.5 9.6 7.7 31.1 28.4 10.7 5.5 6.9 7.8 26.8 29.2 16.3 8.7 18.0 28.0 4.9 25.4 11.0 3.7 30.3 7.3 12.7 2.8 4.7 6.5 8.7 26.4 7.0 7.6 11.6 30.2 7.7 14.5 4.5 7.9 9.7 7.2 25.6 11.4 17.6 14.6 26.0 21.1 28.5 6.4 12.9 18.0 21.8 11.2 13.1 9.6 6.7 9.4 26.5 25.8 16.3 15.4 16.8 11.9 10.2 7.9 4.8 26.2 5.3 13.3 10.4 9.3 18.2 24.5 22.5 9.5 37.5 14.6 20.0 5.7 10.0 16.6 16.2 20.5 5.0 19.8 14.9 15.6 8.9 13.5 13.3 21.5 5.1 35.3 17.6 18.3 9.1 6.6 8.5 28.7 9.8 15.5 22.0 16.7 26.7 15.4 3.9 7.9 3.3 26.1 10.0 10.5 1.4 3.6 0.1 12.3 3.7 11.0 12.7 13.0 11.9 3.5 14.4 13.1 10.6 2.6 10.6 9.3 4.7 5.5 6.6 29.4 30.6 23.6 32.1 31.1 28.4 26.8 29.2 25.4 26.4 30.2 25.6 3.3 12.8 3.9 0.0 1.6 0.0 0.0 0.0 0.0 0.0 6.1 7.1 0.0 0.0 5.0 16.5 0.0 2.2 2.7 0.0 19.6 10.5 0.0 18.3 11.9 1.5 0.0 0.0 0.0 7.8 7.1 4.5 0.0 4.6 0.0 4.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.7 0.0 0.0 15.5 21.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 1.4 1.5 10.0 0.0 0.0 BRINP3 "DBCCR1L, DBCCR1L1, FAM5C" ENSG00000162670 "BMP/retinoic acid inducible neural specific 3" Q76B58 1 190097658-190478404 "Predicted intracellular proteins, Predicted secreted proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;intestine: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 266.7;Excitatory neurons: 333.7;Inhibitory neurons: 129.7;Oligodendrocyte precursor cells: 1079.2" "Group enriched" "Detected in some" 14 "breast cancer: 3.4;glioma: 8.6;prostate cancer: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054693 Uncertain "Secreted in other tissues" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054693: AB_2682575" "unprognostic (3.18e-2)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (3.65e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (9.84e-2)" "unprognostic (4.58e-3)" 0.3 1.7 19.8 0.6 16.8 0.0 1.4 18.7 19.2 0.2 0.0 6.6 4.6 0.2 3.0 1.7 0.4 1.6 5.3 27.1 25.8 2.3 0.0 1.2 0.0 12.5 15.7 0.0 0.0 0.0 0.2 0.0 12.4 6.8 6.7 0.7 1.6 5.1 0.1 0.1 17.9 0.6 13.1 0.0 0.2 3.4 26.0 0.1 2.1 0.0 0.1 0.5 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 16.8 18.7 19.2 27.1 25.8 12.5 15.7 12.4 13.1 26.0 10.4 0.0 0.0 0.0 266.7 0.0 0.0 0.1 0.0 0.0 0.7 0.3 0.4 2.3 0.0 0.0 3.7 0.0 0.0 0.0 2.0 3.9 0.0 63.3 0.0 0.0 0.1 1.2 0.0 333.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 129.7 2.8 0.0 0.0 0.0 10.5 0.0 0.1 0.0 8.4 0.0 0.0 0.0 1079.2 4.3 0.0 10.8 0.0 0.0 1.0 8.1 0.3 0.0 0.1 0.0 0.0 5.8 2.0 0.7 0.1 0.0 0.0 0.0 0.0 5.2 0.1 BSCL2 "GNG3LG, seipin, SPG17" ENSG00000168000 "BSCL2 lipid droplet biogenesis associated, seipin" Q96G97 11 62690275-62709845 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid degradation, Lipid metabolism" "Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 292.1;pituitary gland: 237.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 35.9;Late spermatids: 53.1;Plasma cells: 86.3;Spermatocytes: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 242.1;RPMI-8226: 176.1;SCLC-21H: 181.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042394 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA042394: AB_10794047" "unprognostic (7.78e-2)" "unprognostic (8.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.17e-2)" "unprognostic (3.08e-2)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (9.30e-2)" "unprognostic (4.44e-2)" "unprognostic (5.13e-3)" "unprognostic (2.41e-1)" "prognostic favorable (7.55e-5)" "unprognostic (3.56e-1)" "unprognostic (1.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.96e-1)" 24.9 88.1 126.6 7.4 133.2 12.0 26.2 75.0 155.6 38.2 85.4 24.3 10.8 28.4 156.7 24.1 63.7 21.5 18.7 134.9 292.1 50.8 39.3 26.7 15.3 138.1 139.0 32.7 79.4 61.7 237.0 10.0 203.4 35.4 13.3 52.6 66.1 30.3 30.9 25.1 17.2 13.7 83.1 16.2 37.1 190.3 169.3 14.4 37.9 15.5 8.9 17.5 26.1 89.9 18.0 61.7 49.6 83.8 130.8 41.5 7.2 7.2 34.4 13.6 14.5 9.6 26.3 11.9 16.5 25.2 11.8 62.1 5.2 21.8 7.0 30.7 5.0 10.9 33.4 7.8 27.7 9.7 13.5 27.8 16.6 26.9 10.9 19.7 10.8 33.0 7.8 242.1 19.8 44.0 11.4 21.8 132.4 13.9 13.0 21.3 4.2 176.1 65.0 2.4 181.2 29.4 28.2 13.9 25.3 5.7 41.3 15.3 6.5 16.5 3.7 24.5 4.2 32.2 72.5 16.6 82.4 3.2 14.5 26.6 59.2 34.6 24.7 46.2 27.4 27.5 25.5 26.1 42.4 29.7 25.7 27.0 14.2 41.0 40.3 54.3 33.1 43.3 126.6 133.2 75.0 155.6 134.9 292.1 138.1 139.0 203.4 83.1 169.3 89.9 0.8 16.0 5.6 0.0 7.1 1.7 1.0 1.4 35.9 2.5 3.6 2.2 0.2 1.5 1.6 3.7 0.0 2.4 0.9 1.7 3.9 2.0 25.5 4.8 1.5 2.9 0.0 8.8 0.0 1.1 1.9 9.2 20.4 1.5 2.5 0.7 1.4 2.1 1.9 3.3 0.0 1.6 6.1 2.5 3.1 53.1 2.5 6.2 12.4 0.0 0.7 0.8 1.0 0.0 0.0 0.5 1.6 3.0 86.3 0.9 2.5 6.0 23.9 1.2 6.6 1.2 4.1 32.6 18.1 24.7 4.0 1.5 6.5 0.7 1.2 0.5 BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1535.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1408.0;Syncytiotrophoblasts: 1654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" 378.6 518.8 652.6 154.5 615.4 431.3 313.8 575.6 847.5 320.6 975.8 543.5 231.3 413.3 259.5 245.1 323.1 176.2 1535.0 629.0 606.0 469.7 186.0 253.6 101.9 578.5 611.2 300.7 301.6 255.3 331.2 320.2 599.8 228.8 155.9 189.6 274.8 194.4 472.3 226.6 239.7 164.1 551.0 200.0 455.8 486.0 724.3 92.8 302.1 292.2 74.2 366.9 233.0 581.2 622.6 739.3 339.5 852.3 975.0 426.0 800.4 499.2 507.6 506.1 437.9 607.1 569.4 208.4 564.3 383.5 148.7 967.8 341.0 575.0 129.6 468.1 840.3 150.0 545.5 812.3 683.6 361.6 679.0 455.5 578.5 302.4 304.5 613.1 383.3 198.3 722.9 992.5 298.6 1015.8 261.6 706.6 901.9 353.7 408.3 522.8 301.2 745.2 655.9 412.1 561.0 539.1 984.4 408.1 769.7 257.9 432.3 1118.9 478.7 557.5 353.4 940.1 751.5 639.7 701.8 201.1 1066.9 510.2 712.8 189.0 324.7 348.9 226.4 245.9 200.5 115.0 150.7 218.4 209.6 93.2 114.0 144.7 474.8 173.5 284.2 235.2 192.0 434.0 652.6 615.4 575.6 847.5 629.0 606.0 578.5 611.2 599.8 551.0 724.3 581.2 313.5 22.4 31.5 75.1 101.5 208.6 176.8 668.0 91.0 157.7 202.8 187.6 80.6 128.7 253.4 286.9 204.3 1408.0 156.5 1140.1 146.8 580.9 261.6 156.6 296.6 246.7 255.1 1091.4 35.4 371.4 1095.5 279.8 192.1 190.1 116.2 181.1 132.1 96.9 416.7 139.7 31.4 337.2 510.6 137.8 179.6 600.2 300.4 139.8 506.9 122.7 264.5 495.5 221.4 20.6 30.7 458.0 929.1 336.7 192.4 172.8 450.7 306.7 178.8 269.2 203.8 74.3 235.6 347.9 604.4 127.7 156.7 1654.9 130.9 223.5 478.2 181.4 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 BUD23 "MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT, WBSCR22" ENSG00000071462 "BUD23 rRNA methyltransferase and ribosome maturation factor" O43709 7 73683025-73705161 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 119.9;Endometrial ciliated cells: 133.6;Exocrine glandular cells: 140.8;Pancreatic endocrine cells: 126.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 712.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052185 Approved Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "HPA052185: AB_2681753" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (2.67e-2)" "unprognostic (4.79e-2)" "unprognostic (3.62e-3)" "unprognostic (8.54e-2)" "prognostic unfavorable (9.92e-4)" "unprognostic (1.17e-1)" "unprognostic (9.16e-2)" "unprognostic (9.20e-2)" "unprognostic (6.71e-2)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (5.15e-2)" "unprognostic (1.55e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" 39.8 49.2 34.5 40.0 36.7 58.7 43.4 36.4 39.8 36.3 41.0 48.6 47.0 38.6 72.3 41.7 58.9 34.5 87.9 36.1 39.0 53.3 47.2 38.5 52.6 37.0 36.1 37.8 70.8 49.2 45.1 30.7 36.3 37.8 47.7 20.3 55.9 42.2 128.0 43.8 40.3 41.4 36.4 42.1 44.9 130.0 36.6 44.7 56.5 78.4 51.7 51.9 32.8 38.5 142.1 151.8 53.6 429.2 72.0 64.2 91.1 95.1 83.3 118.5 96.1 211.4 182.6 163.6 48.9 99.5 204.0 97.0 124.8 91.0 108.4 116.6 147.1 72.0 174.8 86.7 91.2 200.3 98.8 57.3 102.2 103.2 93.9 59.7 77.4 130.3 285.4 288.9 103.7 219.6 128.0 277.8 130.2 317.8 172.2 110.5 106.8 712.0 132.5 100.2 163.4 124.4 126.3 329.2 146.5 53.0 207.9 159.0 85.2 101.8 130.3 130.0 208.3 99.5 192.6 275.5 232.3 155.6 218.0 54.8 64.9 60.6 112.0 74.2 124.9 175.3 127.1 122.5 122.9 153.5 132.8 121.5 11.9 125.4 68.0 190.9 150.6 132.6 34.5 36.7 36.4 39.8 36.1 39.0 37.0 36.1 36.3 36.4 36.6 38.5 67.0 44.8 64.5 0.0 26.5 0.0 0.0 0.0 0.0 0.0 75.4 85.7 0.0 0.0 42.7 46.0 0.0 75.7 64.1 0.0 97.8 119.9 0.0 133.6 51.2 28.6 0.0 0.0 0.0 140.8 82.7 24.5 0.0 79.6 46.7 49.2 0.0 0.0 70.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 21.2 0.0 0.0 0.0 0.0 126.0 0.0 0.0 16.5 0.0 0.0 103.5 78.7 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 106.7 28.1 73.0 0.0 0.0 C11orf1 FLJ23499 ENSG00000137720 "Chromosome 11 open reading frame 1" Q9H5F2 11 111878935-111885975 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 402.4;Late spermatids: 1147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038410, HPA057519" Uncertain Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA038410: AB_10672591, HPA057519: AB_2683454" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (1.96e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.30e-1)" "unprognostic (1.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-1)" "unprognostic (9.26e-2)" "unprognostic (3.23e-2)" "unprognostic (1.41e-2)" "unprognostic (2.86e-2)" "prognostic favorable (1.39e-4)" "unprognostic (3.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.97e-1)" "unprognostic (2.08e-1)" 21.5 37.0 25.9 10.4 29.0 18.1 49.2 26.4 36.1 20.5 24.6 26.3 20.4 17.2 64.2 24.0 28.6 19.6 33.0 26.1 27.5 70.3 54.9 16.3 15.1 26.1 26.7 28.0 48.0 39.9 28.4 9.4 26.5 27.4 26.4 22.3 33.0 26.8 16.2 34.8 21.4 14.9 25.7 11.6 30.6 61.2 27.1 20.3 41.1 21.1 17.8 22.7 18.4 27.0 25.1 31.9 40.3 44.6 45.6 34.3 42.0 13.5 34.2 10.9 13.8 54.5 45.6 91.9 63.5 23.2 31.4 28.9 16.5 50.2 17.0 40.6 23.4 30.9 6.9 42.0 28.6 45.7 20.9 63.8 76.9 39.0 74.4 48.4 13.5 96.2 45.3 66.8 36.9 25.0 62.2 70.8 46.3 86.8 48.0 31.5 42.0 127.6 69.4 46.0 36.3 34.1 8.7 31.5 31.3 38.4 63.1 31.8 11.7 40.2 28.8 17.6 19.1 38.8 61.2 136.7 20.3 53.1 24.9 6.5 7.4 9.0 13.0 14.6 24.9 26.0 22.0 17.0 11.1 17.7 34.5 26.5 1.7 16.7 10.1 32.8 17.6 10.2 25.9 29.0 26.4 36.1 26.1 27.5 26.1 26.7 26.5 25.7 27.1 27.0 14.3 25.6 19.8 3.6 22.6 23.7 67.5 60.6 71.2 8.6 56.5 79.6 57.6 28.6 43.4 35.0 6.2 28.9 17.3 15.1 201.5 21.8 402.4 30.5 17.3 15.3 26.4 26.3 3.5 27.2 22.5 16.5 22.4 22.6 29.2 23.3 11.0 43.4 23.0 15.2 4.7 39.8 28.5 7.9 11.4 1147.2 27.4 14.3 24.9 3.7 19.3 43.5 20.6 1.0 3.7 18.9 22.3 24.5 41.9 36.4 40.6 197.9 44.4 15.5 19.7 10.8 17.0 54.4 30.9 53.4 29.5 21.1 22.6 49.2 44.4 72.7 C11orf21 ENSG00000110665 "Chromosome 11 open reading frame 21" Q9P2W6 11 2295628-2303049 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "bone marrow: 50.4;heart muscle: 20.0;lymphoid tissue: 14.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 68.1;dendritic cells: 29.4;Macrophages: 20.3;monocytes: 28.4;NK-cells: 47.4;T-cells: 16.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 51.7;HL-60: 19.7;NB-4: 18.4;THP-1: 12.7;U-937: 22.2" HPA037607 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm Cytosol "HPA037607: AB_10672909" "unprognostic (5.25e-3)" "unprognostic (2.65e-4)" "unprognostic (1.35e-1)" "unprognostic (4.61e-3)" "unprognostic (4.32e-2)" "unprognostic (3.58e-4)" "unprognostic (8.98e-4)" "unprognostic (2.37e-3)" "unprognostic (1.87e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.84e-4)" "unprognostic (8.50e-2)" "unprognostic (9.54e-2)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" 1.4 0.6 0.3 7.1 0.4 50.4 0.6 0.4 0.4 1.6 0.2 0.9 0.6 0.6 0.3 0.6 0.7 2.1 20.0 0.3 0.3 0.7 1.3 4.7 14.0 1.1 0.5 0.2 0.4 0.1 0.3 0.6 0.8 0.6 1.3 0.0 1.5 0.4 1.0 1.3 3.5 1.0 0.6 14.9 2.6 0.3 0.4 3.6 0.9 0.2 7.3 1.1 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 51.7 0.1 0.1 0.5 19.7 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.4 22.2 0.0 80.3 14.9 45.8 23.8 31.4 16.1 4.7 7.8 18.8 17.1 5.8 11.6 16.3 12.6 23.9 58.4 1.7 6.1 16.5 0.3 0.4 0.4 0.4 0.3 0.3 1.1 0.5 0.8 0.6 0.4 1.0 0.2 0.0 4.2 0.0 6.9 0.4 0.0 0.0 0.0 0.0 0.1 0.3 68.1 2.8 0.0 0.0 0.0 0.1 29.4 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 13.9 0.0 0.0 0.2 1.7 0.5 0.0 15.8 0.0 2.5 0.0 3.7 0.0 0.0 0.0 0.0 12.5 15.5 0.0 0.0 20.3 1.8 0.0 28.4 0.0 47.4 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.4 0.0 16.0 0.0 0.0 0.0 C11orf71 FLJ20010 ENSG00000180425 "Chromosome 11 open reading frame 71" Q6IPW1 11 114391443-114400511 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 139.0" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2360.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063943, HPA074787" Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "HPA063943: AB_2685157, HPA074787: AB_2686712" "unprognostic (1.24e-1)" "unprognostic (2.53e-2)" "unprognostic (1.42e-2)" "prognostic favorable (6.94e-4)" "unprognostic (7.35e-2)" "unprognostic (4.53e-2)" "unprognostic (1.83e-1)" "unprognostic (2.30e-3)" "unprognostic (1.58e-1)" "unprognostic (3.04e-3)" "unprognostic (1.39e-2)" "unprognostic (2.85e-2)" "prognostic favorable (7.01e-9)" "unprognostic (5.68e-2)" "unprognostic (5.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.17e-2)" 5.8 10.7 11.8 5.1 13.7 3.7 7.6 12.3 13.8 5.5 10.8 6.9 7.6 5.1 22.6 4.3 7.1 4.4 9.3 11.7 13.9 13.9 22.1 5.9 6.7 14.0 16.7 7.2 8.7 8.9 13.4 3.7 13.2 8.5 6.2 15.9 9.8 5.7 15.0 9.4 7.5 2.9 12.2 9.4 7.3 139.0 12.7 8.9 12.4 15.2 4.7 4.6 4.1 16.0 1.2 3.9 4.2 13.6 6.2 3.6 2.9 0.6 1.7 1.7 1.5 3.0 23.6 6.8 7.8 1.0 8.1 6.3 2.8 2.9 2.1 7.5 1.6 5.1 3.2 6.9 5.9 3.0 5.5 5.9 3.2 2.2 6.7 1.9 2.1 10.8 5.1 6.0 3.2 5.5 5.5 4.6 2.2 5.5 2.5 3.9 3.4 17.3 3.8 3.0 11.6 4.6 15.3 1.8 2.4 4.4 11.5 1.6 2.1 0.4 5.9 4.6 1.2 5.8 10.1 5.2 0.9 6.9 1.7 15.9 15.4 10.3 8.8 9.8 5.5 5.9 5.7 6.0 9.3 8.3 9.5 9.9 12.3 12.1 11.9 12.0 7.1 10.1 11.8 13.7 12.3 13.8 11.7 13.9 14.0 16.7 13.2 12.2 12.7 16.0 12.7 3.2 13.4 5.2 8.0 2.7 15.7 6.3 8.6 10.3 18.3 15.9 19.0 0.0 6.2 5.5 4.2 16.1 6.4 15.0 82.2 15.7 589.6 21.2 8.1 8.7 18.1 7.2 4.7 18.9 3.4 9.5 18.8 12.8 6.3 14.1 0.0 0.0 11.5 13.5 5.6 16.7 10.2 0.0 4.1 2360.8 13.1 13.6 5.4 2.8 11.2 31.5 7.2 4.0 18.5 10.5 15.5 9.1 17.2 9.2 33.0 78.6 18.9 14.1 6.6 7.6 8.0 70.6 9.9 10.4 2.6 14.6 7.4 19.6 12.7 11.4 C13orf46 ENSG00000283199 "Chromosome 13 open reading frame 46" A0A1B0GUA9 13 113953705-113974076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 9.5;stomach 1: 6.9;testis: 12.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Exocrine glandular cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 1.1;RPMI-8226: 1.4;T-47d: 1.0;U-138 MG: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" 1.3 0.0 0.2 0.1 0.1 0.5 0.9 0.0 0.2 0.4 1.4 0.4 0.1 0.2 0.0 0.1 0.5 0.4 0.3 0.5 0.0 0.1 0.3 2.6 0.2 0.3 0.3 0.1 9.5 0.0 0.4 0.0 0.2 1.2 0.1 0.0 1.0 0.0 0.4 0.3 0.3 0.0 0.0 0.3 6.9 12.6 0.3 0.1 2.5 0.0 0.0 1.0 0.3 0.7 0.1 0.0 0.2 0.2 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 1.0 0.1 0.2 1.0 0.6 0.2 0.3 0.0 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.5 0.0 0.3 0.3 0.2 0.0 0.3 0.7 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C17orf75 "NJMU-R1, SRI2" ENSG00000108666 "Chromosome 17 open reading frame 75" Q9HAS0 17 32324565-32350023 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 88.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004061, HPA075333" Approved Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Cytosol" "HPA004061: AB_1078337, HPA075333: " "unprognostic (4.21e-2)" "unprognostic (2.49e-2)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (1.51e-1)" "unprognostic (4.73e-2)" "unprognostic (1.07e-3)" "unprognostic (6.36e-2)" "unprognostic (3.29e-1)" "prognostic favorable (3.13e-4)" "unprognostic (1.92e-2)" "unprognostic (7.80e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.09e-1)" "unprognostic (1.29e-1)" "unprognostic (4.27e-2)" "unprognostic (5.60e-2)" 8.1 15.9 10.9 10.4 11.4 7.5 13.2 12.1 13.5 8.9 12.3 11.7 13.3 12.4 18.7 8.7 15.0 7.0 19.4 10.8 11.7 21.3 14.5 8.7 12.9 11.2 10.9 16.1 13.2 27.8 13.4 10.4 11.8 11.6 12.6 26.1 12.2 10.6 17.5 7.2 10.8 10.4 10.5 9.5 12.9 26.3 11.1 16.0 14.1 14.3 13.2 9.6 8.2 11.2 39.2 33.4 51.0 15.5 13.3 14.5 27.9 25.5 22.4 34.3 29.1 18.2 14.9 23.5 28.6 18.2 52.6 42.5 32.8 27.6 46.6 18.0 37.9 18.7 39.8 39.5 26.6 26.3 14.1 13.4 33.0 25.2 17.4 28.6 25.3 43.6 38.9 31.8 22.8 29.2 76.5 26.9 37.7 23.9 14.7 50.1 31.5 44.0 21.4 18.2 50.4 44.3 21.1 19.1 62.7 37.2 50.4 16.8 19.8 18.8 35.4 9.3 42.4 42.5 51.0 82.9 15.3 23.0 5.7 34.6 12.4 16.4 17.6 12.0 20.1 18.2 16.9 18.3 16.1 19.9 18.2 17.0 3.2 19.0 17.1 12.8 19.6 15.4 10.9 11.4 12.1 13.5 10.8 11.7 11.2 10.9 11.8 10.5 11.1 11.2 12.6 12.8 30.7 7.2 13.8 5.9 13.4 27.8 12.5 25.0 11.3 13.5 25.8 8.6 19.3 14.7 8.4 31.8 10.7 3.8 43.0 16.2 10.0 17.2 8.8 10.5 12.6 13.5 11.1 13.8 18.0 9.8 9.7 10.5 11.4 18.3 6.4 11.0 9.7 32.0 15.0 8.0 28.5 7.5 3.7 6.3 7.5 7.8 5.4 2.8 6.7 17.5 11.3 10.1 8.7 11.8 3.2 8.2 14.0 6.4 6.9 29.9 29.9 23.0 39.5 9.7 13.1 88.0 31.8 12.0 6.1 16.3 15.1 10.5 8.4 8.2 C17orf97 "LIAT1, LOC400566" ENSG00000187624 "Chromosome 17 open reading frame 97" Q6ZQX7 17 410325-431062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 58.8" "Group enriched" "Detected in many" 5 "Early spermatids: 546.2;Late spermatids: 1313.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.0;U-2197: 9.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023583 Approved Approved Nucleoli,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoli Cytosol "HPA023583: AB_1853122" "unprognostic (6.62e-2)" "unprognostic (9.12e-3)" "unprognostic (2.64e-1)" "unprognostic (3.07e-3)" "unprognostic (7.73e-2)" "unprognostic (6.51e-2)" "unprognostic (6.91e-2)" "unprognostic (3.17e-2)" "unprognostic (1.82e-1)" "unprognostic (1.11e-1)" "unprognostic (5.12e-2)" "unprognostic (8.07e-2)" "unprognostic (1.98e-3)" "unprognostic (7.70e-3)" "unprognostic (2.90e-1)" "unprognostic (2.84e-2)" "unprognostic (4.19e-2)" 2.1 5.2 1.2 1.0 1.6 0.7 2.8 0.6 2.4 4.1 2.9 4.0 0.8 3.9 1.8 3.2 8.9 1.8 3.8 1.2 1.0 8.5 2.7 2.8 1.2 1.6 2.6 3.8 2.9 1.9 7.0 0.3 1.3 3.1 1.1 2.7 3.1 2.4 4.7 3.7 2.5 0.6 1.4 1.5 3.0 58.8 1.1 1.9 6.9 0.7 0.6 2.7 2.5 1.2 2.1 3.0 1.4 1.7 0.7 0.6 0.7 1.5 1.0 1.1 0.7 0.0 3.1 0.5 1.1 3.4 0.9 7.0 3.8 0.8 1.1 0.3 0.4 1.5 2.6 0.2 2.5 0.3 0.6 0.7 1.9 2.6 0.3 1.6 1.2 3.4 0.2 0.0 0.7 1.8 5.2 2.7 2.1 6.2 0.9 0.5 0.3 1.9 4.8 1.7 0.4 1.6 1.9 2.6 0.4 2.3 1.6 2.3 1.1 1.4 0.7 9.1 0.6 0.2 0.2 0.0 1.7 0.7 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 1.2 1.6 0.6 2.4 1.2 1.0 1.6 2.6 1.3 1.4 1.1 1.2 1.4 3.2 5.9 2.6 0.8 3.3 3.5 6.5 0.0 4.3 7.7 6.0 6.1 7.2 9.5 20.2 20.9 1.6 0.9 18.4 62.6 13.3 546.2 87.1 6.3 3.3 16.1 5.7 3.3 3.5 0.3 3.5 4.6 8.4 2.5 8.6 2.5 5.3 1.9 1.7 3.1 8.5 14.2 0.0 1.5 1313.1 8.4 2.0 3.6 1.9 3.1 13.5 0.0 0.5 0.9 4.7 6.4 6.4 0.1 4.5 3.8 28.0 55.8 26.4 6.6 3.4 4.6 156.2 12.4 1.8 1.0 0.8 0.8 15.4 10.4 1.6 C18orf32 FLJ23458 ENSG00000177576 "Chromosome 18 open reading frame 32" Q8TCD1 18 49477243-49487252 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 238.5;Late spermatids: 233.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040921 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Vesicles Nucleoplasm "HPA040921: AB_10795423" "unprognostic (5.83e-2)" "unprognostic (5.48e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-2)" "unprognostic (4.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-2)" "unprognostic (6.36e-2)" "unprognostic (4.36e-3)" "unprognostic (2.58e-3)" "unprognostic (2.76e-2)" "prognostic favorable (8.89e-9)" "unprognostic (1.02e-1)" "unprognostic (7.42e-2)" "unprognostic (1.28e-2)" "unprognostic (4.36e-2)" 41.5 66.7 10.8 5.6 13.8 6.8 39.8 15.3 20.0 34.9 8.3 46.0 6.1 35.6 5.6 32.3 34.5 6.6 59.3 11.3 13.5 79.6 86.8 46.5 7.9 14.8 13.0 38.8 47.0 18.5 67.9 6.9 14.0 39.4 10.2 24.6 43.7 8.4 37.9 27.8 39.9 7.3 13.4 39.2 58.1 40.9 13.1 8.5 43.9 7.2 10.4 38.8 32.6 18.7 4.3 3.2 14.4 13.3 12.3 8.8 8.6 5.5 7.6 6.0 6.8 0.5 3.7 4.9 8.6 7.9 9.0 11.1 5.1 10.6 12.6 11.3 4.1 4.2 2.3 5.4 11.2 5.1 11.2 9.9 21.0 5.0 6.1 16.0 12.2 10.1 4.1 11.4 9.9 1.9 4.6 2.5 4.7 4.9 5.9 4.0 3.6 3.8 7.1 5.0 10.7 12.3 5.1 3.4 4.4 19.8 3.1 2.3 13.1 9.6 5.0 1.7 6.9 13.4 24.1 9.1 5.2 5.9 7.1 27.4 8.4 25.8 8.4 8.8 8.7 8.9 6.9 7.7 6.6 7.4 6.6 8.4 41.4 6.2 11.3 9.5 8.2 10.3 10.8 13.8 15.3 20.0 11.3 13.5 14.8 13.0 14.0 13.4 13.1 18.7 20.2 44.8 29.2 0.0 50.8 5.5 4.6 21.2 39.3 35.0 26.2 15.0 5.5 31.5 22.4 23.9 43.8 22.9 33.8 92.9 39.2 87.5 238.5 38.1 21.0 17.5 95.5 20.2 0.0 82.7 17.7 28.7 63.2 30.3 45.6 5.3 23.6 40.4 22.1 18.5 0.0 57.3 32.6 38.0 12.0 233.1 17.1 48.1 23.2 0.0 73.9 41.4 34.0 0.0 0.0 92.3 77.5 10.1 83.0 5.6 92.7 57.2 42.4 36.3 19.7 10.3 22.7 12.7 13.9 58.4 7.7 38.7 43.4 4.5 40.8 5.2 C1D "LRP1, Rrp47, SUN-CoR, SUNCOR" ENSG00000197223 "C1D nuclear receptor corepressor" Q13901 2 68041130-68110948 "Predicted intracellular proteins" "Apoptosis, rRNA processing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037413, HPA037588" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA037413: AB_2675463, HPA037588: AB_10672907" "unprognostic (1.84e-1)" "unprognostic (1.85e-1)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.03e-1)" "unprognostic (1.49e-2)" "unprognostic (4.01e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.90e-2)" "unprognostic (1.29e-2)" "unprognostic (4.24e-3)" "unprognostic (6.18e-2)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.01e-1)" 21.7 25.3 11.6 17.0 11.8 48.1 21.4 11.9 19.0 19.9 12.8 19.1 16.6 20.0 17.0 19.3 18.3 14.7 22.2 12.0 12.8 31.5 33.4 19.0 21.4 11.3 11.8 19.3 15.8 24.0 15.3 17.5 11.6 19.5 14.7 16.6 18.7 15.5 46.9 17.5 18.5 13.7 12.0 21.7 21.4 14.8 12.0 17.5 19.6 31.9 16.5 17.4 28.2 13.9 36.6 20.3 22.0 21.0 22.2 27.0 29.6 48.7 28.1 29.3 22.4 40.8 45.0 45.2 27.2 28.9 28.1 18.0 24.7 20.4 43.1 43.0 36.6 43.5 17.6 46.3 22.3 68.1 54.4 25.0 32.4 22.1 20.9 36.3 22.0 41.4 44.8 41.1 26.6 22.2 51.3 69.6 25.4 29.8 24.4 29.6 28.3 39.9 28.2 29.2 20.5 25.4 15.1 30.0 51.6 26.7 22.2 41.2 30.9 27.9 34.5 34.0 38.9 38.0 40.8 58.6 38.9 41.3 34.2 45.3 17.6 43.7 19.0 23.3 22.5 24.2 22.0 16.6 20.6 21.3 23.4 24.3 34.9 30.3 25.2 19.2 25.3 15.2 11.6 11.8 11.9 19.0 12.0 12.8 11.3 11.8 11.6 12.0 12.0 13.9 65.2 76.9 47.9 13.1 70.7 85.0 83.2 132.8 33.6 34.3 52.9 58.4 36.5 64.3 86.3 64.4 22.9 98.9 76.2 48.1 234.8 83.4 52.4 53.7 47.2 42.9 51.6 121.2 17.7 59.4 82.7 60.2 44.9 46.6 44.3 32.8 43.5 81.7 87.5 35.3 15.9 42.6 109.9 61.9 46.1 21.7 55.6 66.9 56.9 8.4 80.1 57.4 88.6 14.1 21.9 65.6 63.3 59.0 58.5 78.1 57.0 251.4 95.4 36.8 98.6 54.2 65.3 164.5 100.3 44.5 86.2 107.8 62.9 52.2 32.8 109.0 C1orf53 ENSG00000203724 "Chromosome 1 open reading frame 53" Q5VUE5 1 197902630-197907367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 64.6;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.9" "Lineage enriched" "Detected in many" 4 "monocytes: 8.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065352 Approved Vesicles,Aggresome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Aggresome "HPA065352: AB_2685477" "prognostic favorable (1.63e-4)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (2.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.90e-3)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (5.53e-3)" "unprognostic (9.85e-2)" "unprognostic (1.12e-1)" "unprognostic (8.58e-3)" "unprognostic (1.37e-1)" 1.7 9.4 2.6 0.5 2.1 0.8 1.4 1.9 3.6 1.5 5.1 2.8 1.8 1.0 3.1 3.0 0.9 0.8 6.7 2.7 2.2 5.1 15.1 1.9 0.5 2.3 2.6 2.3 2.7 0.4 5.0 0.8 2.1 1.4 1.3 0.5 2.3 0.4 3.7 0.9 1.9 0.8 1.8 1.6 1.8 3.1 3.3 0.3 2.7 1.4 0.3 1.2 1.5 2.5 4.4 6.0 0.4 2.1 3.7 10.5 3.3 7.5 5.4 6.2 3.1 5.4 3.7 8.5 11.8 8.5 1.4 2.0 2.2 1.4 0.6 2.7 15.8 5.0 3.7 8.6 1.0 11.2 6.8 7.1 4.8 1.9 0.8 5.0 2.2 1.8 1.4 2.1 4.7 7.9 0.6 10.1 4.7 6.9 8.7 1.1 3.4 3.1 10.1 6.9 18.4 14.4 9.5 1.6 3.2 2.3 4.5 4.3 5.1 7.2 8.0 10.2 5.2 3.6 2.6 2.2 5.2 3.6 9.0 0.0 2.7 0.0 0.3 8.9 0.0 0.0 0.1 0.6 2.1 0.1 0.3 0.3 0.0 0.0 4.4 0.6 0.1 0.9 2.6 2.1 1.9 3.6 2.7 2.2 2.3 2.6 2.1 1.8 3.3 2.5 0.5 9.6 10.6 0.3 1.6 2.5 4.1 13.1 4.0 2.2 16.3 20.8 11.7 18.6 15.1 22.0 0.0 18.9 0.3 14.8 19.6 9.9 15.7 16.2 6.7 2.0 7.8 4.8 2.0 13.8 10.2 5.5 4.1 12.1 1.3 8.6 2.2 64.6 9.5 3.3 1.5 12.6 14.2 4.1 1.8 2.7 14.0 4.7 8.8 0.0 2.6 11.5 4.1 1.0 0.8 9.3 8.8 10.5 6.0 6.7 10.8 25.8 12.2 3.9 0.0 1.4 6.1 8.6 4.5 12.4 2.8 11.8 1.1 55.8 16.6 5.7 C1orf56 "FLJ20519, MENT" ENSG00000143443 "Chromosome 1 open reading frame 56" Q9BUN1 1 151047751-151051986 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 76.5" "Cell type enhanced" "Detected in all" "dendritic cells: 213.9;Early spermatids: 440.4;Langerhans cells: 245.2;Spermatocytes: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 15.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037429, HPA037430" Enhanced "Secreted to blood" NA NA 87000000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "HPA037429: AB_10671755, HPA037430: AB_2675473" "unprognostic (7.60e-2)" "unprognostic (8.26e-2)" "unprognostic (1.09e-2)" "unprognostic (3.83e-1)" "unprognostic (4.31e-2)" "unprognostic (2.83e-2)" "unprognostic (1.11e-2)" "unprognostic (3.81e-3)" "unprognostic (1.59e-2)" "unprognostic (2.70e-3)" "unprognostic (3.28e-3)" "unprognostic (5.29e-2)" "unprognostic (3.61e-2)" "unprognostic (3.61e-2)" "unprognostic (6.16e-2)" "unprognostic (2.26e-1)" "unprognostic (4.79e-2)" 4.6 10.2 2.1 1.5 2.9 0.6 4.4 3.3 2.5 5.7 3.1 4.9 2.1 5.3 3.2 5.4 5.7 2.6 7.9 1.9 2.2 6.5 8.3 2.9 1.6 2.9 2.8 5.9 7.6 3.4 10.0 1.2 2.6 6.4 0.7 1.9 5.5 3.1 6.5 4.2 3.5 1.2 2.9 4.3 5.5 76.5 2.4 0.4 8.2 2.3 0.4 5.1 5.0 3.2 4.1 8.0 2.7 1.2 4.4 4.2 2.4 2.2 3.2 1.4 1.1 3.5 5.6 0.9 3.5 2.4 3.0 5.3 1.5 0.3 0.8 5.2 1.7 1.0 5.9 4.3 3.0 1.1 0.9 3.1 1.7 2.1 0.8 2.7 2.1 1.7 2.2 2.1 1.3 15.9 1.5 2.8 4.5 3.2 4.4 1.3 2.7 2.9 1.2 2.3 3.6 7.0 7.0 3.7 5.5 5.0 7.3 3.0 2.2 1.9 3.3 5.1 2.0 4.7 4.0 12.2 3.5 0.6 2.4 223.6 22.7 50.4 90.8 54.5 70.3 46.7 78.6 80.8 19.7 51.7 64.8 90.8 69.8 59.0 48.2 28.1 48.9 4.1 2.1 2.9 3.3 2.5 1.9 2.2 2.9 2.8 2.6 2.9 2.4 3.2 57.6 6.4 10.1 19.2 56.8 64.6 38.1 20.8 4.6 20.2 80.3 46.2 7.1 40.0 17.1 42.3 20.9 53.8 213.9 15.6 39.2 21.2 440.4 12.3 20.4 34.4 14.8 12.4 27.6 14.5 35.9 34.5 4.1 12.5 38.8 10.7 66.8 38.3 30.9 18.5 25.6 14.4 16.2 95.5 245.2 80.7 28.6 50.4 88.9 24.4 78.0 20.0 119.4 26.7 37.2 32.4 19.5 25.6 50.9 35.7 8.8 36.5 10.8 26.6 26.3 41.4 35.3 308.8 13.7 3.9 83.3 89.5 90.7 11.5 15.0 46.2 C1QA ENSG00000173372 "Complement C1q A chain" P02745 1 22636628-22639678 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 1092.6" "Group enriched" "Detected in many" 9 "Hofbauer cells: 1663.2;Kupffer cells: 5007.4;Macrophages: 1874.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39 "intermediate monocyte: 226.1;non-classical monocyte: 181.7" "Lineage enriched" "Detected in many" 60 "monocytes: 226.1" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;NB-4: 1.4;RPMI-8226: 7.1;SCLC-21H: 3.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002350, CAB009823" Supported "Secreted to blood" NA NA 2700000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009823: AB_2228238, HPA002350: AB_1078552" "unprognostic (1.97e-1)" "unprognostic (1.14e-2)" "unprognostic (1.98e-3)" "unprognostic (3.07e-2)" "unprognostic (6.10e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.13e-1)" "unprognostic (1.67e-2)" "unprognostic (1.99e-1)" "unprognostic (4.42e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.58e-6)" "unprognostic (1.54e-1)" "unprognostic (2.11e-3)" "unprognostic (2.75e-2)" "unprognostic (7.30e-2)" 375.1 235.6 86.6 134.0 85.6 53.9 95.9 85.8 135.3 75.8 120.0 142.8 172.3 43.1 26.0 58.3 75.6 172.4 74.8 82.9 93.7 56.2 208.8 404.3 532.3 126.7 110.1 37.5 34.3 26.2 46.3 256.3 110.3 47.1 120.2 4.1 48.1 54.6 14.8 21.8 190.1 195.0 107.5 1092.6 90.8 38.2 109.4 100.3 36.5 49.3 68.0 257.5 30.4 131.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.3 0.0 0.0 0.5 0.2 7.1 0.0 0.0 3.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.4 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 5.2 0.1 0.1 226.1 0.0 0.0 0.1 0.1 3.7 0.0 0.0 0.0 0.5 0.3 181.7 0.0 0.0 9.7 86.6 85.6 85.8 135.3 82.9 93.7 126.7 110.1 110.3 107.5 109.4 131.6 17.4 35.3 55.8 0.0 19.0 18.4 2.3 0.0 2.2 0.4 5.1 24.6 8.9 37.1 18.0 0.0 0.0 8.7 2.7 0.5 0.0 0.0 4.5 0.2 0.5 46.0 1.8 41.0 0.0 0.2 11.3 9.6 0.0 0.2 21.5 0.2 76.1 26.2 1663.2 0.0 0.0 0.1 0.0 5007.4 291.4 9.9 13.1 1874.2 26.6 20.6 16.7 0.3 0.0 0.0 0.1 0.0 0.1 0.4 2.8 1.3 0.1 1.1 15.3 0.8 78.9 7.4 4.6 0.7 2.1 4.2 16.8 18.2 11.8 0.0 0.2 1.3 C1QB ENSG00000173369 "Complement C1q B chain" 1 22652762-22661637 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lung: 546.4;lymphoid tissue: 990.2" "Group enriched" "Detected in many" 28 "Hofbauer cells: 1451.0;Kupffer cells: 4559.7;Macrophages: 1747.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 71 "intermediate monocyte: 140.6;non-classical monocyte: 101.2" "Lineage enriched" "Detected in many" 85 "monocytes: 140.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052116 Approved "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA052116: AB_2681735" "unprognostic (1.42e-1)" "unprognostic (3.36e-2)" "unprognostic (5.61e-3)" "unprognostic (8.20e-2)" "unprognostic (5.93e-2)" "unprognostic (4.09e-1)" "unprognostic (1.25e-1)" "unprognostic (2.35e-1)" "unprognostic (2.87e-2)" "unprognostic (2.21e-1)" "unprognostic (2.63e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (4.14e-2)" "unprognostic (7.76e-3)" "unprognostic (4.83e-2)" "unprognostic (2.35e-2)" 439.2 229.0 95.8 149.4 94.2 53.5 87.1 97.2 148.7 65.4 132.6 162.0 186.0 27.7 26.4 63.0 50.5 194.9 62.6 89.8 107.7 18.3 243.4 546.4 514.6 161.0 143.3 39.6 40.0 28.5 1.8 249.2 138.4 28.0 146.0 7.8 44.9 51.2 5.3 6.1 186.1 261.4 138.2 990.2 88.0 39.9 142.2 72.0 23.6 38.6 58.4 255.8 1.1 185.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.8 0.4 0.0 0.0 0.5 0.3 0.6 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 1.7 0.0 0.0 140.6 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.4 0.8 101.2 0.0 0.0 5.3 95.8 94.2 97.2 148.7 89.8 107.7 161.0 143.3 138.4 138.2 142.2 185.8 13.8 12.8 22.1 0.0 17.1 6.2 2.1 0.0 1.8 1.2 4.9 23.1 5.5 24.3 10.5 3.7 0.0 6.6 2.7 0.6 0.0 0.0 3.3 0.1 0.2 65.9 0.0 32.8 0.1 0.0 9.6 5.9 0.0 0.1 11.4 0.1 52.1 26.0 1451.0 0.0 0.1 0.0 0.0 4559.7 92.1 7.8 8.4 1747.2 0.0 34.7 5.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 2.3 1.0 0.3 1.1 3.6 3.9 59.2 4.0 3.2 0.4 0.9 5.7 4.5 9.6 6.1 0.2 0.0 1.5 C1QC C1QG ENSG00000159189 "Complement C1q C chain" P02747 1 22643633-22648110 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 950.7" "Group enriched" "Detected in many" 7 "Hofbauer cells: 1356.5;Kupffer cells: 2134.6;Macrophages: 1040.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "intermediate monocyte: 57.2" "Lineage enriched" "Detected in single" 541 "monocytes: 57.2" "Cell line enhanced" "Detected in some" "NB-4: 1.0;RPMI-8226: 2.6;U-266/70: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001471, CAB009828" Supported "Secreted to blood" NA NA 513000000 2100000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009828: AB_2067541, HPA001471: AB_1078553" "unprognostic (2.97e-1)" "unprognostic (6.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (7.40e-2)" "unprognostic (2.38e-1)" "unprognostic (1.98e-1)" "unprognostic (1.40e-1)" "unprognostic (1.66e-2)" "unprognostic (7.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (1.06e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" 285.2 196.0 60.1 159.7 58.6 43.5 70.5 64.8 97.1 51.9 90.6 133.2 179.9 36.3 13.5 55.3 67.4 155.4 58.6 54.9 75.5 41.2 169.6 290.8 370.2 124.7 105.4 32.1 37.5 22.1 39.6 204.9 105.0 37.8 91.3 3.9 51.6 44.5 12.9 18.3 195.7 164.7 100.4 950.7 94.8 33.9 106.0 75.7 29.2 31.8 50.7 191.8 24.6 159.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 1.0 0.2 0.0 0.0 0.6 0.2 2.6 0.0 0.0 0.4 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 1.0 0.0 0.1 0.1 0.1 0.0 0.0 1.3 0.0 0.0 57.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.4 0.0 0.0 1.2 60.1 58.6 64.8 97.1 54.9 75.5 124.7 105.4 105.0 100.4 106.0 159.3 13.4 6.4 5.2 0.3 13.7 8.9 1.1 0.0 2.8 0.6 4.9 24.5 1.6 15.7 3.1 0.0 0.0 5.8 2.3 0.4 0.0 0.0 3.2 0.0 0.1 34.5 0.0 27.2 0.0 0.2 9.5 4.4 0.0 0.1 5.1 0.1 25.4 6.6 1356.5 0.0 0.1 0.1 0.0 2134.6 202.4 3.6 6.2 1040.7 7.2 29.0 23.6 0.4 0.0 0.0 0.0 0.0 1.1 1.2 0.9 0.4 0.0 0.4 0.7 0.6 46.0 2.5 1.8 0.4 0.8 3.3 6.5 9.9 3.5 0.0 0.0 0.7 C1QTNF2 CTRP2 ENSG00000145861 "C1q and TNF related 2" Q9BXJ5 5 160347754-160370641 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 23.7;Leydig cells: 23.3;Peritubular cells: 29.7;Skeletal myocytes: 16.9;Smooth muscle cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "basophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Cell line enhanced" "Detected in some" "RH-30: 34.4;U-138 MG: 15.1;U-2 OS: 8.3;WM-115: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061290 Uncertain Approved "Golgi apparatus,Centrosome" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Centrosome" "HPA061290: AB_2684468" "unprognostic (2.28e-2)" "unprognostic (5.61e-2)" "unprognostic (4.09e-2)" "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (6.20e-2)" "unprognostic (1.46e-1)" "unprognostic (1.94e-1)" "unprognostic (5.91e-2)" "unprognostic (8.33e-2)" "unprognostic (3.23e-2)" "unprognostic (8.32e-2)" "unprognostic (2.11e-5)" "unprognostic (5.40e-5)" "unprognostic (1.14e-1)" "unprognostic (6.75e-2)" "unprognostic (1.10e-2)" 2.8 0.6 0.9 0.7 0.9 0.1 1.9 1.2 1.3 4.7 0.1 2.5 1.2 3.3 1.1 1.4 2.3 1.8 3.9 0.9 0.8 0.6 0.4 2.4 0.3 0.3 1.3 1.3 0.3 0.2 0.5 0.8 0.2 1.9 1.1 0.2 1.3 1.0 1.9 1.4 2.3 1.8 0.2 0.6 2.0 1.8 2.5 0.1 2.1 2.1 0.3 2.1 2.6 0.8 0.3 0.0 0.5 0.1 0.0 0.0 0.0 3.9 5.3 0.9 3.3 0.1 0.9 0.0 0.1 1.4 0.6 0.2 0.1 0.4 0.2 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.3 0.0 0.1 0.0 34.4 0.0 0.0 0.2 0.0 0.8 1.0 0.1 0.2 0.1 0.4 0.1 0.2 15.1 8.3 1.5 4.4 0.1 0.0 0.0 0.5 0.0 6.8 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.9 0.9 1.2 1.3 0.9 0.8 0.3 1.3 0.2 0.2 2.5 0.8 2.0 0.0 0.0 0.0 0.0 6.5 0.2 0.2 0.6 0.8 0.3 0.4 1.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.1 0.0 0.1 1.0 4.2 0.0 0.0 0.6 0.2 0.3 23.7 0.5 0.2 0.0 0.2 1.1 0.0 1.1 0.0 6.2 0.1 0.0 0.0 6.2 0.4 23.3 0.5 5.4 1.0 0.6 0.1 0.0 1.0 0.3 0.1 0.1 29.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 16.9 22.8 0.1 0.5 0.6 3.8 0.8 0.3 2.1 0.1 0.3 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C2orf15 MGC29762 ENSG00000273045 "Chromosome 2 open reading frame 15" Q8WU43 2 99141707-99151669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Proximal tubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 12.6;SCLC-21H: 12.2" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.61e-2)" "unprognostic (7.88e-2)" "unprognostic (4.22e-2)" "unprognostic (4.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.99e-2)" "unprognostic (5.37e-2)" "unprognostic (9.05e-3)" "unprognostic (1.62e-2)" "prognostic favorable (4.95e-4)" "unprognostic (2.54e-3)" "unprognostic (1.04e-1)" "prognostic favorable (1.23e-4)" "unprognostic (2.06e-1)" "unprognostic (4.22e-4)" "unprognostic (5.08e-1)" "unprognostic (2.97e-2)" 0.4 0.7 1.5 0.8 1.5 1.3 3.5 3.3 1.8 2.4 1.7 2.1 4.1 1.2 6.0 1.4 3.9 1.8 0.3 1.4 1.6 5.4 0.5 1.4 1.5 1.5 1.5 0.8 3.1 6.1 0.7 1.1 1.7 1.3 2.4 3.8 2.7 1.8 0.3 2.0 3.2 0.3 1.2 1.0 3.8 1.4 2.1 1.2 6.3 0.0 1.6 1.7 0.1 2.5 9.8 1.5 0.3 1.3 0.2 0.0 7.2 0.0 0.7 0.5 0.3 10.1 7.0 4.3 3.0 0.0 0.8 6.0 1.4 1.1 0.0 0.8 4.5 0.3 1.8 6.8 0.1 1.5 1.8 0.2 2.2 0.0 0.7 0.4 0.0 5.5 0.4 0.9 0.4 8.5 1.2 1.9 2.2 5.3 2.1 0.7 0.2 4.8 9.9 12.6 12.2 1.5 1.0 10.2 0.4 1.7 8.2 0.4 0.0 0.5 0.5 0.3 0.4 2.9 4.8 1.5 0.2 1.4 0.1 0.3 0.3 0.2 2.0 0.2 4.7 1.8 3.2 2.5 0.1 2.0 4.3 2.2 0.9 3.8 0.1 0.4 1.7 1.2 1.5 1.5 3.3 1.8 1.4 1.6 1.5 1.5 1.7 1.2 2.1 2.5 0.4 3.2 3.1 0.7 2.5 1.1 1.7 2.1 0.0 5.6 5.4 4.6 0.4 2.8 2.2 7.3 6.2 6.8 0.7 0.8 15.6 5.5 1.8 3.7 0.4 0.9 1.2 0.8 3.3 2.9 0.7 0.6 1.1 2.5 0.0 1.3 0.4 0.1 0.6 6.7 2.5 2.9 0.0 0.0 1.4 0.3 0.6 0.5 0.0 0.0 0.5 4.1 0.0 0.5 2.8 2.8 3.7 0.4 0.7 1.5 3.7 9.8 7.9 7.7 0.0 0.9 0.5 3.4 3.7 0.9 1.4 2.1 1.8 1.6 3.4 1.3 C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.1" "Cell type enhanced" "Detected in some" "granulocytes: 36.8;Hofbauer cells: 161.5;Kupffer cells: 139.7;Macrophages: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 898.6;eosinophil: 450.8;intermediate monocyte: 273.6;non-classical monocyte: 371.3" "Group enriched" "Detected in many" 20 "granulocytes: 898.6;monocytes: 371.3" "Cell line enriched" "Detected in some" 9 "HMC-1: 148.0" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" 18.0 10.6 3.8 40.1 4.0 22.9 6.7 4.7 5.7 6.8 4.4 7.4 6.6 3.8 1.5 3.9 5.9 16.2 4.4 3.9 6.9 3.1 10.8 18.6 12.4 10.1 6.3 3.7 6.0 3.3 2.5 22.0 9.0 3.3 6.8 0.8 5.6 4.3 1.4 2.0 9.7 15.6 8.3 21.4 5.3 2.1 7.8 4.9 2.4 2.6 5.1 15.2 2.7 15.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.9 0.5 3.8 0.0 0.0 1.6 0.0 0.0 2.2 0.1 0.0 0.0 0.1 0.0 0.0 12.0 0.0 0.0 1.4 15.6 148.0 0.7 0.0 0.2 0.4 0.3 0.7 1.2 4.0 8.2 0.7 0.0 0.7 5.2 0.1 0.0 0.0 0.1 3.1 15.1 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 6.6 0.6 0.5 0.4 0.1 0.3 0.3 0.0 0.4 8.5 6.4 0.4 898.6 105.0 450.8 21.8 273.6 26.9 0.2 10.6 14.5 31.1 0.3 2.0 7.8 14.0 4.1 371.3 2.8 11.0 76.0 3.8 4.0 4.7 5.7 3.9 6.9 10.1 6.3 9.0 8.3 7.8 15.6 0.7 0.0 3.0 0.3 1.1 0.5 0.1 0.1 0.0 0.1 0.3 0.9 0.6 1.5 2.5 0.0 2.1 0.7 5.9 0.0 0.0 0.0 3.0 0.0 0.1 6.6 0.0 0.8 0.4 0.2 1.0 0.6 0.0 0.0 36.8 0.0 1.8 0.8 161.5 0.0 0.3 0.0 0.0 139.7 19.8 4.2 1.2 105.7 0.0 8.4 16.2 0.0 8.2 0.0 0.2 0.0 0.0 0.0 2.6 0.0 0.0 0.2 0.7 0.4 19.7 0.7 1.0 0.0 0.2 0.0 0.6 1.5 8.6 0.1 0.0 0.0 C3orf33 "AC3-33, FLJ31139" ENSG00000174928 "Chromosome 3 open reading frame 33" Q6P1S2 3 155762617-155806278 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037663 Uncertain "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "HPA037663: AB_10672610" "unprognostic (1.18e-1)" "unprognostic (9.39e-3)" "unprognostic (1.48e-1)" "unprognostic (1.66e-3)" "unprognostic (1.31e-1)" "unprognostic (7.27e-2)" "unprognostic (6.31e-3)" "unprognostic (3.28e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic favorable (6.48e-7)" "unprognostic (3.19e-1)" "unprognostic (1.79e-1)" "unprognostic (2.24e-2)" "unprognostic (1.56e-1)" 2.7 10.7 5.2 1.3 5.6 2.0 4.2 5.3 7.8 4.0 6.2 3.1 2.6 3.7 5.8 1.7 3.9 2.3 6.1 5.5 5.5 6.2 3.1 3.3 1.6 5.4 5.5 4.5 6.7 7.5 4.9 1.3 5.4 4.4 2.3 2.7 3.2 3.9 4.9 1.3 2.2 3.3 5.4 2.3 3.1 4.1 5.8 1.5 8.7 4.4 1.0 2.7 2.5 5.4 5.5 7.5 3.6 4.9 0.3 4.4 1.5 2.4 3.5 2.2 5.2 2.6 6.9 0.9 5.3 2.3 3.3 0.8 3.7 0.0 3.9 2.7 5.4 3.3 1.0 7.0 6.0 4.8 1.1 3.4 4.0 2.4 4.6 2.8 3.8 5.5 5.4 2.4 3.8 4.1 4.9 4.0 4.6 5.2 1.8 4.8 1.8 5.2 12.2 2.7 2.6 3.6 5.3 6.7 4.6 1.8 9.8 5.7 2.3 2.5 1.8 5.5 5.9 4.1 4.3 0.0 1.8 4.4 2.6 2.1 1.2 0.2 4.0 1.1 5.1 1.8 3.1 3.6 2.1 1.4 3.9 4.1 0.1 4.0 0.8 1.7 2.2 2.1 5.2 5.6 5.3 7.8 5.5 5.5 5.4 5.5 5.4 5.4 5.8 5.4 1.6 3.2 6.7 13.7 1.5 1.3 5.2 4.7 5.2 8.5 3.1 2.7 11.9 5.7 6.7 0.0 6.2 4.2 0.9 1.8 5.9 3.7 6.6 1.5 2.7 2.3 3.6 3.8 14.9 3.3 3.1 4.8 1.1 1.4 7.0 2.8 2.5 3.3 2.4 6.7 14.9 3.8 4.1 0.3 2.0 5.4 6.2 1.4 1.8 3.7 0.6 15.6 6.2 11.6 10.7 1.4 2.5 7.9 2.2 5.1 1.0 7.0 3.5 7.6 0.0 8.4 4.1 14.5 14.8 2.7 1.4 3.7 2.8 3.8 3.7 2.5 C6orf89 "BRAP, FLJ25357" ENSG00000198663 "Chromosome 6 open reading frame 89" Q6UWU4 6 36871870-36928964 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 340.1;Late spermatids: 699.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 351.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012548 Uncertain NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 89: Fibroblasts - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "HPA012548: AB_1845748" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (1.69e-2)" "unprognostic (1.69e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.77e-5)" "unprognostic (3.75e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-3)" "unprognostic (8.42e-3)" 37.4 37.5 24.6 27.3 28.8 37.6 32.0 26.1 24.6 45.8 22.7 33.8 28.1 36.8 50.0 35.4 38.5 33.1 49.7 26.7 31.2 32.9 34.1 32.8 24.7 29.0 29.4 44.9 46.2 54.3 28.2 33.3 29.1 37.0 37.1 13.4 42.3 47.6 36.6 24.2 27.5 45.0 29.9 24.9 33.4 47.5 30.2 30.2 58.2 44.3 31.4 31.7 26.5 35.3 37.9 22.9 31.1 44.8 111.0 76.2 18.3 73.1 91.6 50.5 55.2 23.7 39.2 33.6 55.5 150.6 54.1 40.3 38.3 46.0 72.9 60.4 33.2 48.8 23.3 26.8 55.5 39.6 48.3 66.0 56.2 62.0 58.9 60.4 44.5 60.1 93.8 90.1 79.0 37.7 43.5 15.0 11.6 43.1 25.7 21.1 30.9 61.1 33.7 33.2 54.9 39.5 48.8 23.5 50.8 25.8 56.0 53.3 52.7 72.3 41.2 57.6 57.4 48.4 63.8 351.0 32.6 55.8 77.3 28.1 16.7 20.9 18.1 16.4 17.9 9.8 14.8 16.8 14.7 9.1 10.2 11.2 27.2 11.2 22.5 9.2 16.4 14.4 24.6 28.8 26.1 24.6 26.7 31.2 29.0 29.4 29.1 29.9 30.2 35.3 31.2 38.5 56.8 22.9 24.6 6.8 23.9 28.8 19.4 15.5 24.6 19.0 67.1 41.5 31.6 38.6 10.4 34.0 26.6 39.2 19.6 41.2 340.1 24.9 36.1 36.1 17.4 56.0 38.4 58.1 41.6 37.7 27.5 33.7 30.4 52.6 25.0 45.5 40.0 23.5 35.3 27.9 32.6 29.8 12.5 699.2 45.1 27.2 10.6 29.0 24.9 53.9 28.8 31.7 54.5 56.3 27.9 50.8 44.1 26.6 30.5 20.1 28.3 12.8 19.7 35.8 36.9 33.7 38.5 23.5 8.9 46.0 28.5 50.8 25.9 26.1 C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA024812: AB_10599490, HPA026104: AB_10600875" "prognostic unfavorable (2.77e-4)" "unprognostic (6.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (8.95e-4)" "unprognostic (4.75e-2)" "unprognostic (3.51e-1)" "unprognostic (2.45e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" 16.5 42.1 32.3 13.1 32.1 18.2 24.8 33.5 41.7 17.7 28.3 21.7 13.1 20.4 27.1 19.5 22.8 16.5 22.3 32.0 33.1 18.7 17.1 15.0 18.2 33.3 34.3 40.7 20.8 34.0 5.6 21.1 32.8 18.8 33.4 24.6 16.4 24.2 16.9 17.4 10.2 19.6 32.4 12.2 11.5 13.1 32.7 19.3 33.2 26.0 18.4 18.8 8.9 33.3 28.3 32.7 45.8 22.7 51.3 35.5 17.2 16.6 41.7 42.0 23.3 9.2 39.2 30.3 55.3 40.5 19.5 22.4 67.5 41.2 45.3 15.0 48.4 38.1 32.1 11.5 53.1 30.6 15.1 41.0 60.4 43.0 96.8 34.5 28.1 44.9 75.4 26.3 46.1 42.4 86.3 12.3 31.8 89.1 55.2 51.2 14.9 46.6 44.1 16.3 44.1 39.1 44.3 39.3 39.0 26.1 41.1 29.1 13.8 27.5 37.3 24.2 37.8 21.7 16.9 72.2 65.9 47.0 55.1 1.0 13.7 8.7 16.3 17.4 18.4 13.4 16.2 17.8 19.6 13.3 21.3 15.6 1.4 28.2 16.0 18.4 12.6 16.3 32.3 32.1 33.5 41.7 32.0 33.1 33.3 34.3 32.8 32.4 32.7 33.3 67.8 28.9 27.2 4.9 34.8 44.4 32.8 31.9 24.5 48.3 52.8 47.9 18.4 45.8 33.8 25.8 31.3 36.9 45.3 180.5 62.6 79.5 5.6 49.9 55.1 50.2 35.3 17.5 5.7 64.9 40.2 41.7 20.9 53.0 21.5 58.5 37.1 66.8 28.7 50.5 6.0 36.4 14.2 21.5 21.2 5.6 37.9 23.0 16.0 7.5 32.3 61.2 45.3 4.0 6.0 55.3 37.7 38.7 20.4 48.1 22.1 66.1 26.6 54.5 26.3 32.8 37.9 26.2 34.8 25.4 42.9 24.9 23.6 94.9 53.0 28.5 C8orf48 FLJ25402 ENSG00000164743 "Chromosome 8 open reading frame 48" Q96LL4 8 13566869-13568288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Group enriched" "Detected in many" 5 "Early spermatids: 33.3;Late spermatids: 51.9;Spermatocytes: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 13.5;U-87 MG: 11.5;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026107, HPA027440" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA026107: AB_10600765, HPA027440: AB_10601678" "unprognostic (1.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.07e-2)" "unprognostic (9.01e-2)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (4.84e-3)" "unprognostic (7.70e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-1)" "unprognostic (1.41e-3)" "unprognostic (7.74e-4)" "unprognostic (1.78e-1)" "unprognostic (8.42e-3)" "unprognostic (8.70e-2)" 1.1 0.2 1.1 0.6 2.2 0.0 1.8 1.3 1.6 1.3 0.2 0.5 0.4 1.1 2.9 0.6 1.8 1.2 1.3 1.2 1.2 1.2 0.8 1.2 0.4 2.2 1.5 0.6 0.4 0.3 0.5 0.6 2.6 0.2 0.4 4.8 0.4 0.4 0.1 1.3 0.4 0.9 1.2 0.2 0.9 7.0 1.7 0.2 4.4 0.4 0.2 0.8 0.3 2.9 0.0 0.1 1.8 0.0 6.0 6.0 0.0 5.5 6.1 2.9 4.9 0.0 0.0 0.0 0.0 2.9 13.5 0.6 0.2 1.1 5.7 0.0 0.6 0.6 0.0 0.0 2.1 0.0 0.9 1.9 3.6 3.9 1.0 0.7 3.8 0.0 0.1 0.0 7.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 3.2 0.0 0.2 6.3 2.0 0.0 0.0 1.7 5.1 4.9 6.0 5.0 0.0 0.0 0.0 11.5 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.2 1.3 1.6 1.2 1.2 2.2 1.5 2.6 1.2 1.7 2.9 1.0 0.0 0.0 2.0 0.0 1.0 0.0 1.0 0.0 0.2 0.9 0.8 0.3 0.0 0.9 0.0 2.1 0.0 0.0 0.1 0.0 2.7 33.3 1.8 3.0 0.7 0.0 0.0 0.6 1.1 0.0 2.7 0.0 0.2 0.0 0.3 1.1 0.5 0.1 0.0 0.3 0.0 2.0 0.0 0.0 51.9 5.0 0.2 5.4 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 3.0 0.0 0.0 0.0 3.6 1.9 4.3 6.6 1.2 4.5 18.2 2.3 0.8 0.4 0.0 0.1 3.4 0.0 0.1 C9orf116 "MGC29761, PIERCE1, RbEST47" ENSG00000160345 "Chromosome 9 open reading frame 116" Q5BN46 9 135495181-135501734 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 97.2;testis: 62.5" "Group enriched" "Detected in many" 4 "Early spermatids: 520.9;Endometrial ciliated cells: 442.5;Late spermatids: 579.4;Respiratory ciliated cells: 610.3" "Cancer enhanced" "Detected in all" "endometrial cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 41.3;T-47d: 41.9;U-2197: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA021439, HPA065287" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA021439: AB_1845799, HPA065287: AB_2732732" "unprognostic (9.02e-2)" "unprognostic (1.36e-2)" "unprognostic (1.93e-1)" "prognostic favorable (3.53e-5)" "unprognostic (7.43e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (4.23e-1)" "unprognostic (2.58e-1)" "unprognostic (5.30e-2)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (4.23e-3)" "unprognostic (3.86e-2)" "unprognostic (8.75e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" 2.6 16.3 11.9 0.8 12.8 0.9 3.1 10.7 13.0 5.5 24.5 2.1 1.0 4.2 25.7 1.9 97.2 2.8 2.0 14.0 13.6 9.5 3.5 9.2 0.7 15.8 19.7 2.8 6.5 6.8 16.9 1.5 15.9 4.2 1.2 10.1 3.4 6.3 1.5 1.8 1.4 1.2 15.4 1.9 3.1 62.5 14.5 0.6 8.1 0.9 1.2 2.7 1.5 13.0 11.0 18.7 8.1 12.7 3.5 7.4 1.6 7.3 5.1 8.7 5.9 7.1 10.9 1.9 9.5 4.9 4.7 7.4 9.1 4.1 7.4 0.5 8.0 0.0 21.0 22.1 9.7 1.5 5.0 5.2 3.2 4.4 1.4 7.1 4.2 8.6 10.3 1.4 4.2 41.3 5.7 1.9 17.1 17.2 21.5 8.7 3.9 6.9 21.0 7.7 7.9 8.3 10.3 4.4 1.2 3.7 41.9 1.8 2.1 5.0 6.5 42.9 2.9 4.7 12.6 1.8 14.7 0.7 1.5 0.0 0.8 0.0 0.5 0.5 1.2 0.2 0.4 0.4 0.3 0.4 0.7 0.5 0.0 0.6 0.1 0.1 0.5 0.3 11.9 12.8 10.7 13.0 14.0 13.6 15.8 19.7 15.9 15.4 14.5 13.0 1.2 9.6 7.8 2.3 1.9 0.9 1.8 39.7 2.2 5.0 11.7 9.8 1.7 15.7 46.3 14.7 14.6 11.5 0.7 0.5 11.7 26.0 520.9 442.5 6.6 2.1 1.2 1.3 2.1 7.8 3.4 5.2 4.6 23.9 1.3 12.0 0.7 1.6 3.6 3.3 2.2 1.0 38.7 1.2 1.4 579.4 8.1 1.3 0.0 0.0 2.0 13.2 0.0 1.0 0.2 6.9 1.7 7.5 3.6 2.4 1.3 58.8 610.3 19.9 0.0 1.4 15.0 133.8 20.0 1.3 0.3 4.5 1.6 41.4 1.7 3.1 CAAP1 "C9orf82, CAAP, FLJ13657" ENSG00000120159 "Caspase activity and apoptosis inhibitor 1" Q9H8G2 9 26840685-26892803 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020404, HPA024029, HPA024100" Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020404: AB_1845841, HPA024029: AB_1845842, HPA024100: AB_1845843" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.73e-2)" "unprognostic (6.74e-2)" "unprognostic (8.83e-2)" "unprognostic (1.35e-2)" "unprognostic (4.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.27e-5)" "unprognostic (1.46e-1)" "unprognostic (1.89e-1)" "prognostic favorable (7.94e-9)" "unprognostic (2.74e-2)" "unprognostic (7.57e-2)" "unprognostic (1.46e-1)" "unprognostic (1.43e-2)" 7.0 20.4 4.3 10.5 4.5 7.7 10.8 4.8 6.2 9.1 11.0 18.6 17.4 8.2 16.9 11.3 9.2 9.8 5.7 4.4 5.1 16.3 23.8 7.8 14.7 4.4 4.3 6.6 10.8 18.9 7.4 9.7 4.3 10.6 19.5 8.6 11.2 9.5 7.1 10.2 12.7 10.0 4.0 8.5 11.2 12.6 4.6 14.2 27.4 7.5 15.1 10.6 6.8 4.7 24.2 14.9 24.3 23.9 15.9 13.4 18.5 17.4 17.1 16.4 20.1 4.4 14.9 28.6 17.5 14.9 9.4 12.8 25.3 17.0 22.4 39.0 15.4 49.6 22.6 28.2 26.4 21.7 23.9 13.7 21.4 12.7 29.7 18.5 27.8 18.4 14.1 21.0 19.1 13.9 33.8 9.0 32.2 23.8 12.3 23.1 10.9 19.0 42.6 17.7 19.4 38.5 15.9 17.5 16.3 21.5 14.9 25.6 16.7 0.0 24.5 10.1 16.4 9.6 19.2 33.0 8.0 22.3 10.3 14.9 11.3 8.2 16.2 17.6 20.9 18.8 17.7 18.9 18.4 18.7 14.7 15.3 1.4 20.1 15.7 17.2 18.8 16.0 4.3 4.5 4.8 6.2 4.4 5.1 4.4 4.3 4.3 4.0 4.6 4.7 13.9 22.4 21.6 42.1 20.3 9.9 11.3 18.4 15.9 10.8 18.2 14.6 9.7 14.3 27.6 31.3 8.4 18.3 16.4 28.1 58.7 20.6 18.8 25.6 15.3 14.9 15.5 21.7 34.0 19.8 14.7 13.4 18.8 25.5 18.3 15.8 10.4 34.3 12.1 8.4 42.5 26.0 26.4 11.1 10.3 5.4 8.4 17.7 8.8 26.2 15.6 22.1 12.3 41.2 33.8 22.6 23.1 6.4 26.0 17.5 13.4 29.5 23.7 12.7 13.1 16.9 14.8 41.9 18.4 31.6 14.6 10.8 20.1 28.0 32.1 12.6 CABP7 MGC57793 ENSG00000100314 "Calcium binding protein 7" Q86V35 22 29720003-29731833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 38.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 28.6" "Group enriched" "Detected in some" 4 "glioma: 2.3;ovarian cancer: 1.0;pancreatic cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 10.3;SCLC-21H: 9.7;SH-SY5Y: 3.1;U-2 OS: 3.1" "Group enriched" "Detected in all" 4 "cerebellum: 74.4;hippocampal formation: 204.8;midbrain: 60.3;pons and medulla: 110.0" "Region enhanced" "Detected in all" "hippocampal formation: 51.0" HPA016439 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA016439: AB_2669357" "unprognostic (1.88e-1)" "unprognostic (4.75e-2)" "unprognostic (1.18e-1)" "unprognostic (5.37e-2)" "unprognostic (4.55e-1)" "unprognostic (2.29e-4)" "unprognostic (2.05e-3)" "unprognostic (7.96e-2)" "unprognostic (8.69e-3)" "unprognostic (3.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (7.44e-7)" "unprognostic (1.25e-4)" "unprognostic (3.60e-2)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" 0.1 5.6 3.1 0.0 3.0 0.2 0.1 19.8 35.0 0.1 0.6 0.8 0.4 0.1 0.0 0.1 0.1 0.0 0.2 38.2 4.2 0.2 0.3 0.1 0.1 27.7 14.8 0.1 3.1 0.0 0.4 0.0 30.0 0.4 0.0 1.0 0.2 0.0 0.1 0.2 1.5 0.0 22.2 0.4 0.3 0.6 3.9 0.0 0.3 0.0 0.0 0.1 0.1 16.5 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 10.3 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.0 0.0 9.7 3.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 3.1 0.1 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.1 3.1 3.0 19.8 35.0 38.2 4.2 27.7 14.8 30.0 22.2 3.9 16.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 28.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 1.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 CADM1 "BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1" ENSG00000182985 "Cell adhesion molecule 1" Q9BY67 11 115169218-115504957 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 287.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 464.8;Astrocytes: 980.7;Bipolar cells: 566.6;Muller glia cells: 489.9;Oligodendrocyte precursor cells: 676.5;Oligodendrocytes: 622.8;Rod photoreceptor cells: 759.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.0;myeloid DC: 8.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.1;T-cells: 8.0" "Cell line enhanced" "Detected in many" "CACO-2: 294.7;WM-115: 187.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037266 Enhanced Supported "Cell Junctions" NA NA 220000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "CAB037266: AB_532287" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "prognostic favorable (1.32e-4)" "unprognostic (4.11e-3)" "unprognostic (1.50e-1)" "unprognostic (2.75e-3)" "unprognostic (1.13e-2)" "unprognostic (1.77e-1)" "unprognostic (2.67e-1)" "unprognostic (6.61e-3)" "unprognostic (9.22e-2)" "unprognostic (2.92e-3)" "unprognostic (1.77e-2)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (5.40e-2)" 7.1 29.9 46.9 6.1 59.2 0.4 17.0 78.7 53.0 21.3 6.1 11.7 7.8 17.4 103.7 12.6 22.6 12.1 25.7 47.6 57.4 29.1 65.3 72.0 14.1 41.1 40.1 12.3 16.0 56.6 26.0 37.9 44.6 15.2 8.1 287.7 38.0 28.0 7.2 10.9 8.8 8.6 30.3 8.0 12.5 50.5 55.8 8.6 69.7 8.1 14.6 13.1 4.8 38.0 0.4 23.3 25.6 0.1 0.0 0.0 0.1 24.1 41.1 3.1 0.3 294.7 26.1 0.0 75.9 36.5 25.2 4.8 4.8 27.4 2.0 1.0 38.3 0.0 7.8 114.5 0.3 0.1 56.5 0.0 38.6 0.0 63.8 16.5 1.1 17.3 0.0 2.7 4.3 19.3 20.0 0.6 24.0 0.3 0.0 0.1 0.4 61.6 44.8 0.9 50.2 107.1 0.0 25.4 21.7 102.4 92.4 1.3 0.0 2.3 44.9 23.3 13.0 64.9 98.9 18.7 36.3 0.2 187.5 0.2 0.0 0.0 8.0 0.0 3.4 1.5 2.9 2.1 8.1 0.3 0.1 1.8 0.0 0.5 0.1 0.0 4.7 1.9 46.9 59.2 78.7 53.0 47.6 57.4 41.1 40.1 44.6 30.3 55.8 38.0 14.0 464.8 195.3 980.7 6.5 20.6 26.7 2.8 19.4 566.6 22.1 22.5 61.7 34.3 27.5 36.8 350.3 71.6 6.8 1.5 11.7 39.2 189.1 88.5 6.0 10.6 7.8 5.3 301.7 2.0 5.0 13.2 3.6 126.9 24.1 36.8 2.9 45.9 36.8 30.3 310.9 2.1 4.1 8.5 20.9 224.0 5.9 14.2 44.4 60.0 13.3 489.9 2.1 676.5 622.8 9.3 0.5 4.1 88.9 38.5 0.3 8.2 8.7 759.5 0.0 13.3 11.7 55.2 23.0 9.2 23.4 32.2 8.1 5.2 4.3 13.5 CALCA "CALC1, CGRP, CGRP-alpha" ENSG00000110680 "Calcitonin related polypeptide alpha" "P01258, P06881" 11 14966668-14972351 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, Transporters" Hormone "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "parathyroid gland: 178.3;thyroid gland: 154.2" "Cell type enriched" "Detected in some" 64 "Ionocytes: 2368.1" "Cancer enriched" "Detected in many" 7 "lung cancer: 64.7" "Region enhanced" "Detected in many" "pons: 34.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "pons and medulla: 57.9" "HPA059886, HPA064453" Enhanced Supported "Secreted to blood" NA NA 51500 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA059886: , HPA064453: " "unprognostic (1.97e-1)" "prognostic unfavorable (4.49e-5)" "unprognostic (5.99e-2)" "unprognostic (2.42e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.74e-2)" "unprognostic (2.53e-3)" "unprognostic (1.02e-2)" 0.7 0.2 0.6 1.5 0.6 0.0 0.2 0.6 0.5 0.2 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 1.1 0.3 0.8 46.4 37.5 2.4 0.1 20.9 7.0 0.1 0.4 178.3 0.8 0.0 34.4 2.5 0.1 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.5 3.0 0.2 0.2 0.6 0.3 154.2 0.0 0.0 4.3 0.4 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.5 0.3 0.8 20.9 7.0 34.4 1.5 0.6 10.4 0.1 0.0 0.0 0.0 0.2 0.3 0.4 35.4 0.0 0.0 0.0 0.1 0.4 0.0 0.3 36.8 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.3 0.0 0.0 0.7 4.4 0.3 0.0 0.0 0.0 2368.1 0.0 4.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.2 0.0 0.0 0.4 5.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 CALCB "CALC2, CGRP-II, FLJ30166" ENSG00000175868 "Calcitonin related polypeptide beta" P10092 11 14904997-15082342 "FDA approved drug targets, Plasma proteins, Predicted secreted proteins" Hormone "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 18.9;thyroid gland: 20.7" "Group enriched" "Detected in some" 4 "Melanocytes: 5.4;Spermatogonia: 5.1" "Group enriched" "Detected in some" 5 "colorectal cancer: 1.2;endometrial cancer: 2.4;thyroid cancer: 0.9" "Group enriched" "Detected in many" 4 "hypothalamus: 6.8;medulla oblongata: 8.9;midbrain: 11.6;pons: 18.9;white matter: 4.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 5.8;Karpas-707: 10.4;SH-SY5Y: 3.5;U-266/70: 16.0" "Region enriched" "Detected in some" 7 "pons and medulla: 9.6" "Group enriched" "Detected in many" 5 "amygdala: 30.4;basal ganglia: 74.3;hypothalamus: 50.1;midbrain: 33.9;pons: 41.7" HPA059886 Supported "Secreted to blood" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "HPA059886: " "unprognostic (7.84e-2)" "unprognostic (4.07e-1)" "unprognostic (3.92e-1)" "prognostic unfavorable (3.42e-5)" "unprognostic (2.02e-1)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "unprognostic (3.32e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-1)" "unprognostic (1.02e-2)" "unprognostic (2.33e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.33e-1)" 0.3 0.0 0.1 0.3 0.2 0.0 0.2 0.5 0.6 0.2 0.1 1.4 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.3 6.8 1.0 0.8 0.1 0.1 8.9 11.6 0.1 1.5 0.3 2.2 0.1 18.9 0.1 0.2 0.1 0.3 0.0 0.8 0.1 0.4 0.1 2.3 0.1 0.1 0.3 1.0 0.0 20.7 0.1 0.1 0.0 0.1 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.2 5.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 1.9 0.0 0.4 0.1 0.0 10.4 0.0 0.0 0.0 0.6 2.9 0.1 0.1 0.4 0.0 0.2 0.0 0.0 1.1 3.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 16.0 0.6 0.4 2.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.6 0.3 6.8 8.9 11.6 18.9 2.3 1.0 4.7 0.0 0.0 0.0 0.3 0.2 1.3 0.1 0.0 0.0 0.0 0.6 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.4 0.0 0.0 0.4 0.2 0.9 0.5 0.2 0.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.3 0.0 0.0 5.4 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.9 5.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 CANX "CNX, IP90, P90" ENSG00000127022 Calnexin P27824 5 179678628-179731641 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 817.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 528.3;SK-MEL-30: 790.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004738, HPA009433, HPA009696" Enhanced Enhanced "Endoplasmic reticulum" NA NA 13000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "CAB004738: AB_626784, HPA009433: AB_1078380, HPA009696: AB_1078379" "unprognostic (6.56e-2)" "unprognostic (9.34e-3)" "prognostic favorable (1.38e-4)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" "unprognostic (1.41e-2)" "unprognostic (4.66e-3)" "unprognostic (8.57e-2)" "unprognostic (4.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-3)" "unprognostic (4.48e-2)" "unprognostic (2.28e-1)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "prognostic unfavorable (3.17e-4)" "unprognostic (2.15e-1)" 128.3 112.8 15.0 36.3 17.6 76.0 110.6 18.8 31.1 121.4 25.1 108.7 45.0 137.7 171.7 106.7 109.8 6.2 137.5 13.8 24.1 121.4 193.2 112.7 18.4 24.7 24.1 129.6 209.7 9.6 96.5 75.0 20.2 96.0 62.6 68.0 123.3 17.8 111.6 83.5 97.4 85.0 19.2 73.2 115.2 75.0 17.9 9.0 159.2 53.6 16.6 112.0 95.6 22.6 13.0 91.5 89.5 53.0 295.4 229.3 37.9 261.4 342.8 341.2 298.2 148.2 49.6 309.3 351.0 127.8 121.4 18.7 120.2 121.1 405.9 64.6 6.3 63.0 247.8 22.9 399.9 82.9 50.0 39.1 313.5 118.6 528.3 56.1 93.9 23.9 43.2 99.9 39.9 51.2 40.9 15.1 9.4 11.7 6.4 43.2 71.3 24.9 252.1 82.8 24.4 8.0 62.7 16.7 790.3 182.7 267.3 16.3 234.7 49.9 56.5 36.1 200.2 19.7 87.2 46.1 53.3 50.4 46.5 51.8 61.8 17.4 29.9 38.9 34.4 14.4 21.2 25.0 47.6 10.0 15.3 15.6 9.6 32.1 30.1 38.7 16.4 74.1 15.0 17.6 18.8 31.1 13.8 24.1 24.7 24.1 20.2 19.2 17.9 22.6 187.0 198.7 296.6 53.5 109.4 148.5 115.4 181.3 152.0 117.4 245.8 153.5 537.0 185.8 247.0 182.1 158.4 162.5 148.6 174.3 49.0 173.6 225.5 160.9 253.9 204.0 178.0 133.3 45.5 153.5 245.8 202.8 156.5 255.5 197.9 137.7 157.5 438.7 227.7 159.9 77.0 250.0 134.3 206.4 215.6 817.5 159.1 218.3 176.1 44.0 181.1 213.8 84.5 63.3 79.4 153.1 125.1 191.1 327.3 249.5 188.2 196.4 294.3 160.9 92.1 114.6 211.2 158.4 72.7 182.3 161.8 244.8 105.8 183.1 251.0 157.8 CAPN1 "CANP, CANPL1, muCANP, muCL" ENSG00000014216 "Calpain 1" P07384 11 65180566-65212006 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 276.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 516.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005992 Enhanced Supported Cytosol NA NA 9100000 "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA005992: AB_1845924" "unprognostic (2.07e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (7.23e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.33e-1)" "prognostic favorable (7.06e-8)" "unprognostic (5.70e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.98e-1)" 44.8 43.1 27.8 51.9 26.1 66.5 48.4 29.7 30.1 80.9 28.3 78.6 80.4 56.3 27.5 276.2 92.3 55.5 53.1 27.7 33.0 53.1 44.3 56.9 57.0 41.4 31.5 44.5 71.7 36.6 40.8 56.2 43.4 62.1 57.6 9.6 118.7 67.4 84.8 125.1 88.1 45.3 33.9 50.2 65.5 6.1 37.9 49.5 71.5 55.3 86.4 83.4 117.4 27.4 285.6 147.9 42.9 97.2 77.9 104.3 127.0 84.1 144.2 103.0 74.9 94.8 250.2 71.2 136.0 179.3 111.1 409.8 60.9 366.9 32.2 76.4 44.1 170.8 80.4 93.7 76.2 40.6 228.0 107.3 196.8 85.9 43.2 92.6 178.5 50.6 103.1 55.9 87.4 181.8 83.1 130.6 120.5 145.2 133.8 80.7 43.0 43.2 138.1 516.5 76.2 55.7 87.4 331.4 80.3 45.8 142.8 77.9 147.1 73.1 50.5 159.0 38.5 33.8 26.9 86.6 127.5 48.8 82.3 87.6 57.5 77.9 39.4 51.2 31.0 30.8 30.7 35.8 48.4 31.7 17.6 24.9 33.1 34.8 30.4 38.1 35.9 74.8 27.8 26.1 29.7 30.1 27.7 33.0 41.4 31.5 43.4 33.9 37.9 27.4 27.3 25.6 27.9 21.5 39.6 59.9 127.3 120.5 56.9 10.7 44.7 36.6 22.0 74.4 81.0 77.3 20.9 238.5 61.4 184.2 39.2 180.5 0.5 41.9 26.3 31.3 44.3 58.3 15.9 115.8 111.7 39.6 57.6 58.2 46.9 48.6 37.9 36.7 88.7 21.9 15.2 76.9 59.0 51.2 34.0 2.0 43.5 67.1 48.0 14.0 112.7 38.5 61.8 6.6 1.9 179.4 124.1 50.8 17.7 78.6 155.6 34.6 71.1 16.2 39.5 25.3 36.7 0.5 2.8 102.0 68.9 196.6 40.2 35.4 125.3 156.6 CARD11 "BIMP3, CARMA1" ENSG00000198286 "Caspase recruitment domain family member 11" Q9BXL7 7 2906142-3043867 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Immunity "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.3" "Cell type enhanced" "Detected in many" "B-cells: 34.9;dendritic cells: 47.2;Microglial cells: 49.6;NK-cells: 28.8;Pancreatic endocrine cells: 24.9;Plasma cells: 26.7;T-cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 31.4" "Cell line enhanced" "Detected in many" "Daudi: 122.7;K-562: 50.1;RT4: 91.4;U-698: 108.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052984 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA052984: AB_2682005" "unprognostic (3.12e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (4.81e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.31e-1)" "unprognostic (5.65e-2)" "unprognostic (5.11e-2)" "unprognostic (2.09e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-8)" "unprognostic (3.74e-2)" "unprognostic (4.75e-2)" "unprognostic (1.31e-1)" "prognostic favorable (1.10e-4)" 1.3 3.1 6.9 21.8 1.5 18.5 1.2 1.8 1.5 2.3 1.0 2.4 3.7 1.3 0.2 1.3 2.2 8.8 1.0 1.3 4.9 1.6 1.6 4.7 47.3 4.2 8.4 1.3 1.4 0.7 0.9 0.5 3.7 1.4 2.3 0.2 3.3 1.6 0.6 0.7 18.3 0.6 3.0 31.5 7.5 1.7 14.0 20.9 1.5 0.2 29.5 17.1 1.3 4.6 16.7 2.6 0.1 0.1 0.0 0.0 12.2 0.1 0.0 0.5 0.0 32.4 35.5 122.7 29.2 0.0 0.0 27.2 0.0 0.4 0.3 42.1 1.1 0.1 3.1 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.8 23.1 13.3 50.1 0.0 0.0 0.3 4.7 0.0 44.9 20.6 0.1 5.9 0.1 30.7 11.4 91.4 0.3 1.5 0.1 0.2 0.1 17.7 0.2 2.5 15.4 0.2 11.8 0.1 0.1 12.3 0.1 108.0 0.0 0.0 0.2 0.5 0.0 0.0 7.7 0.0 7.2 5.4 4.4 5.2 0.9 6.2 2.9 5.3 0.2 5.5 0.0 31.4 3.5 2.9 6.9 1.5 1.8 1.5 1.3 4.9 4.2 8.4 3.7 3.0 14.0 4.6 0.5 0.0 0.0 0.7 34.9 0.0 0.3 0.3 0.6 0.6 0.3 0.4 2.0 0.0 0.3 1.8 0.0 0.0 47.2 0.7 0.0 4.6 0.2 0.4 0.3 0.6 0.0 0.8 2.1 5.3 0.0 1.6 14.3 0.7 5.7 8.6 0.4 0.2 1.5 0.0 1.6 0.3 0.0 2.4 1.8 0.4 0.3 5.4 3.6 49.6 1.0 0.1 28.8 1.0 0.6 24.9 0.0 0.0 26.7 0.3 0.0 0.1 1.0 0.2 0.0 0.3 0.9 1.5 0.2 0.0 0.3 0.0 28.6 4.5 0.4 8.1 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 CCDC126 FLJ23031 ENSG00000169193 "Coiled-coil domain containing 126" Q96EE4 7 23597382-23644708 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.6" "Group enriched" "Detected in all" 18 "Early spermatids: 642.3;Late spermatids: 490.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 479.0" "Lineage enriched" "Detected in all" 23 "granulocytes: 479.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010969, HPA026883" Uncertain Approved "Golgi apparatus" "Secreted to blood" NA NA 39000000 "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" "HPA010969: , HPA026883: AB_1846131" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (5.96e-3)" "unprognostic (1.16e-2)" "unprognostic (3.90e-1)" "unprognostic (9.30e-2)" "unprognostic (1.42e-2)" "unprognostic (3.44e-2)" "unprognostic (3.29e-2)" "unprognostic (7.35e-3)" "unprognostic (5.90e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (3.28e-1)" 6.5 7.5 3.7 4.5 4.1 7.6 8.4 6.5 4.9 6.6 2.5 5.2 8.6 7.2 4.8 5.9 6.4 5.9 5.0 3.6 4.6 7.2 11.6 6.1 8.9 5.0 5.2 6.8 8.4 11.7 4.3 4.5 4.5 5.5 6.1 8.4 5.4 5.5 7.1 4.8 7.0 6.2 4.6 6.3 6.5 34.6 4.7 5.4 9.4 10.0 8.8 6.3 4.4 4.1 6.0 4.1 8.9 11.3 14.6 8.1 20.4 7.4 7.3 6.2 9.0 4.3 1.9 12.8 11.3 6.2 11.8 3.4 3.9 3.5 8.1 2.7 5.1 2.2 1.6 5.6 5.8 5.9 10.9 8.7 10.0 2.0 1.9 5.2 8.4 5.3 5.2 3.5 7.6 2.8 4.1 7.1 4.2 7.9 5.1 2.7 14.0 3.9 6.5 2.7 5.4 10.2 7.6 7.2 5.6 13.8 6.1 5.4 10.2 3.7 6.5 8.4 5.9 9.9 10.5 9.2 4.1 8.5 20.2 479.0 18.0 86.7 14.7 17.0 17.6 20.7 15.8 17.0 15.6 19.3 19.2 15.0 35.2 16.8 17.1 3.2 19.3 15.6 3.7 4.1 6.5 4.9 3.6 4.6 5.0 5.2 4.5 4.6 4.7 4.1 17.3 6.4 8.1 12.7 12.8 19.1 7.9 8.0 13.6 14.1 15.4 10.7 9.0 12.8 8.2 12.9 8.4 10.2 9.3 7.3 7.9 10.1 642.3 11.1 9.0 10.8 15.0 4.8 14.0 9.1 6.8 11.5 13.3 9.5 7.0 3.7 10.8 15.2 6.9 8.4 17.4 8.7 16.2 7.9 9.6 490.0 11.5 9.5 14.2 12.2 11.4 7.7 14.4 18.6 20.1 10.4 7.3 14.3 12.8 8.3 8.4 8.9 14.6 14.1 13.1 12.0 12.9 31.1 26.3 12.1 23.7 20.2 11.3 29.2 5.9 6.9 CCDC91 "DKFZp779L1558, FLJ11088, p56" ENSG00000123106 "Coiled-coil domain containing 91" Q7Z6B0 12 28133249-28581511 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 18 "Early spermatids: 2093.1;Late spermatids: 7910.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038169 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Nucleoplasm "HPA038169: AB_10672506" "unprognostic (6.25e-2)" "unprognostic (4.25e-2)" "unprognostic (3.67e-2)" "unprognostic (1.91e-2)" "unprognostic (6.71e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.98e-2)" "unprognostic (2.44e-2)" "unprognostic (4.62e-2)" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (7.69e-4)" "unprognostic (1.05e-1)" "unprognostic (2.44e-2)" "unprognostic (5.85e-2)" "unprognostic (2.38e-1)" 17.5 18.3 15.0 13.0 15.8 12.3 16.1 23.2 29.3 11.5 3.5 14.4 12.1 17.8 17.3 14.3 12.3 14.6 30.9 16.6 12.3 20.2 14.3 12.0 16.4 20.7 13.8 17.7 27.1 30.8 12.1 8.5 20.7 15.1 12.6 27.1 13.6 14.0 41.6 10.2 13.1 13.0 11.1 13.6 17.1 34.5 14.6 21.7 24.6 21.7 13.7 16.6 10.5 20.7 21.2 14.8 13.4 0.4 13.6 12.6 25.1 17.5 18.5 15.1 19.3 8.4 27.6 11.0 14.7 20.9 9.0 23.7 12.3 28.2 22.6 29.7 10.2 36.2 29.4 7.7 21.3 35.0 17.1 12.5 27.6 15.0 43.7 28.5 12.3 19.2 33.4 36.0 14.6 7.6 34.8 29.7 27.5 16.2 13.5 21.1 38.7 18.3 24.6 14.3 11.3 20.4 32.7 10.9 55.4 36.4 21.3 27.3 9.3 31.8 22.1 31.5 10.3 44.4 52.5 30.1 27.6 28.0 18.4 21.8 2.3 3.6 5.1 4.5 6.7 6.7 6.5 7.4 3.4 5.2 7.6 7.0 0.7 7.1 5.9 4.1 8.4 3.4 15.0 15.8 23.2 29.3 16.6 12.3 20.7 13.8 20.7 11.1 14.6 20.7 23.4 38.5 41.0 129.3 47.2 34.9 37.4 49.5 34.7 61.5 42.1 36.8 80.8 20.0 40.8 22.0 45.9 14.0 48.4 26.0 43.0 46.2 2093.1 36.9 19.0 19.7 38.4 19.1 199.3 47.3 16.3 24.8 21.4 26.2 40.4 21.9 11.7 26.7 30.6 45.4 266.0 23.9 28.5 35.0 39.3 7910.6 57.8 39.0 37.4 135.9 35.7 52.0 53.5 152.8 221.0 33.8 25.0 51.9 34.2 33.6 25.5 35.0 54.5 74.9 39.5 28.6 31.7 72.0 39.0 19.9 40.5 16.0 50.6 28.5 18.3 33.6 CCDC9B "C15orf52, FLJ43339" ENSG00000188549 "Coiled-coil domain containing 9B" Q6ZUT6 15 40331452-40340967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.0;Collecting duct cells: 20.2;Ductal cells: 30.0;Pancreatic endocrine cells: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 4.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.3" "Cell line enhanced" "Detected in many" "HaCaT: 122.5;hTERT-RPE1: 110.8;WM-115: 138.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040484, HPA041834" Approved Approved Nucleoplasm,Cytosol NA NA 77000 "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA040484: AB_10794742, HPA041834: AB_10795643" "unprognostic (5.57e-3)" "unprognostic (1.85e-1)" "unprognostic (2.60e-3)" "unprognostic (2.33e-2)" "unprognostic (1.48e-2)" "unprognostic (2.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.04e-3)" "unprognostic (1.55e-1)" "unprognostic (3.48e-1)" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" 4.9 10.3 9.5 7.7 13.1 2.8 8.1 10.9 10.7 12.0 15.0 73.4 9.9 23.9 7.3 33.2 10.8 12.0 53.0 9.0 12.7 10.2 5.0 12.3 3.3 13.1 12.6 4.0 25.3 11.3 10.2 3.9 12.7 16.2 12.5 4.3 28.3 22.7 67.4 15.4 18.1 24.2 11.6 5.6 22.3 8.3 12.7 1.3 45.2 65.1 5.9 25.9 16.7 12.6 50.0 6.8 0.0 0.4 1.1 4.6 2.5 14.8 14.6 16.1 15.6 0.5 44.7 0.3 20.1 47.8 58.6 122.5 0.2 40.4 15.1 0.0 0.3 14.9 64.4 4.7 8.5 0.2 2.8 5.7 9.0 6.9 20.3 110.8 11.6 0.8 0.1 0.7 27.9 0.0 0.5 0.0 0.2 23.1 12.7 0.0 4.2 0.2 48.0 2.8 0.1 3.6 8.8 19.1 8.4 0.2 1.9 2.3 62.1 29.7 47.2 7.9 39.8 0.0 0.1 0.6 36.2 2.8 138.3 4.3 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 0.4 0.1 0.2 0.0 0.2 9.5 13.1 10.9 10.7 9.0 12.7 13.1 12.6 12.7 11.6 12.7 12.6 2.7 12.8 10.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.5 3.0 0.0 0.0 1.3 20.2 0.0 0.0 0.2 0.0 1.9 30.0 0.0 1.8 0.4 0.6 0.0 0.0 0.0 3.7 0.1 0.6 0.0 2.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 CCL5 "D17S136E, MGC17164, RANTES, SCYA5, SISd, TCP228" ENSG00000271503 "C-C motif chemokine ligand 5" P13501 17 35871491-35880793 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.1;lymphoid tissue: 135.2" "Group enriched" "Detected in many" 8 "dendritic cells: 2049.9;NK-cells: 2344.0;T-cells: 1947.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 6788.6;memory CD8 T-cell: 7164.3" "Group enriched" "Detected in all" 7 "NK-cells: 2041.1;T-cells: 7164.3" "Cell line enhanced" "Detected in some" "HL-60: 94.1;NB-4: 539.9;THP-1: 139.9;U-937: 120.1" CAB078447 Enhanced "Secreted to blood" NA NA 20100000 2900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB078447: AB_223462" "unprognostic (3.91e-3)" "unprognostic (1.50e-3)" "unprognostic (8.63e-2)" "prognostic favorable (1.34e-5)" "unprognostic (1.36e-3)" "unprognostic (6.37e-3)" "unprognostic (8.70e-2)" "unprognostic (2.64e-2)" "prognostic favorable (2.42e-4)" "unprognostic (3.26e-3)" "unprognostic (1.64e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (3.61e-7)" "unprognostic (1.70e-2)" "unprognostic (7.55e-2)" "unprognostic (8.56e-3)" "unprognostic (3.73e-2)" 17.2 17.1 3.9 36.3 4.0 122.1 19.5 3.8 6.5 15.5 5.4 27.7 48.7 15.7 14.4 15.8 14.0 42.9 8.9 3.9 3.7 7.5 28.4 57.4 135.2 7.3 4.3 16.9 7.0 3.0 3.8 6.3 6.4 10.4 25.6 0.3 33.5 7.9 4.8 4.0 84.5 10.5 5.8 123.9 47.9 4.6 4.7 29.5 11.5 2.7 33.4 31.4 9.5 6.1 0.7 0.5 0.2 0.0 0.5 0.4 0.8 0.3 4.0 17.8 20.8 0.4 1.7 0.3 1.6 0.9 1.3 0.9 0.0 0.0 2.3 6.5 0.3 0.0 1.5 0.6 0.5 94.1 0.8 0.1 0.2 5.5 0.3 0.0 0.2 0.1 0.1 12.5 0.2 0.6 0.1 539.9 0.5 0.0 0.0 0.6 0.2 14.0 0.2 0.5 0.1 0.5 0.2 1.2 13.4 0.5 0.2 139.9 0.3 0.6 0.3 0.6 0.4 14.2 6.6 0.8 0.4 120.1 1.3 657.8 30.0 35.8 6788.6 21.3 4221.0 61.3 1394.5 7164.3 49.8 41.6 332.4 4032.4 189.9 2041.1 26.1 46.5 25.9 6664.4 3.9 4.0 3.8 6.5 3.9 3.7 7.3 4.3 6.4 5.8 4.7 6.1 22.4 99.3 244.4 0.3 55.2 7.4 1.3 6.0 4.6 1.3 19.9 18.2 5.4 21.5 41.7 1.8 0.0 1.8 2049.9 3.1 1.9 6.3 1.2 5.5 5.4 24.2 1.8 106.3 0.5 0.2 7.1 26.0 46.9 6.7 80.8 0.2 45.0 7.0 33.8 0.0 0.3 3.5 0.0 48.0 25.0 0.1 0.3 256.3 12.4 2.8 38.5 0.4 2344.0 0.0 0.4 1.6 6.9 0.4 179.5 1.7 2.4 6.7 29.2 1.1 0.0 6.5 28.2 1.1 1.2 5.5 6.3 16.0 1947.0 0.1 3.5 1.9 CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 74.6;lymphoid tissue: 73.1;testis: 69.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 67.9;Early spermatids: 228.5;Erythroid cells: 123.6;Extravillous trophoblasts: 128.3;Spermatocytes: 288.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Golgi apparatus" "CAB009575: AB_2072392, HPA008873: AB_1078604" "unprognostic (2.69e-2)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.96e-2)" "unprognostic (1.77e-1)" "unprognostic (4.65e-2)" "prognostic unfavorable (2.83e-4)" "prognostic unfavorable (4.63e-4)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (4.48e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.96e-1)" "unprognostic (1.41e-1)" "unprognostic (3.98e-2)" "unprognostic (4.44e-1)" 1.0 1.1 0.4 12.2 1.1 74.6 2.9 0.7 0.7 2.9 1.1 14.3 14.1 2.6 0.3 16.1 1.1 1.9 0.7 0.6 0.7 1.1 1.4 2.2 33.0 1.3 1.0 0.8 0.7 0.2 0.3 11.4 1.0 1.6 16.8 0.3 2.8 0.4 0.7 9.4 12.0 6.4 0.7 7.1 5.6 69.4 1.1 73.1 1.0 0.4 43.7 3.6 5.6 2.2 132.5 112.1 188.6 47.1 8.5 16.6 97.5 104.8 69.9 165.2 135.6 187.8 81.1 122.1 75.4 71.8 97.2 160.1 181.4 92.6 157.8 124.1 92.4 153.1 127.3 108.1 2.5 118.1 98.6 6.3 12.6 71.4 91.9 32.7 114.1 147.0 163.1 194.5 128.2 96.5 137.9 177.2 138.6 58.5 65.2 157.5 260.0 124.4 53.3 91.9 115.2 75.9 148.9 80.2 97.3 147.9 139.4 120.4 58.5 81.6 134.4 90.5 210.5 84.2 133.2 213.8 53.6 267.1 117.9 0.0 0.1 0.7 0.1 0.0 0.3 2.1 4.6 5.0 3.0 1.7 0.0 0.1 0.8 3.6 0.1 0.1 22.7 2.1 0.4 1.1 0.7 0.7 0.6 0.7 1.3 1.0 1.0 0.7 1.1 2.2 0.3 0.0 0.6 0.0 6.8 4.8 2.8 11.5 1.8 0.2 2.5 3.3 0.5 0.0 3.2 0.0 0.0 67.9 1.6 4.1 0.0 0.7 228.5 5.3 3.1 3.9 3.0 123.6 0.7 0.2 128.3 7.2 7.1 5.9 0.0 29.9 6.1 1.1 29.9 0.0 0.8 10.1 20.3 10.6 3.3 53.5 4.4 7.9 0.0 0.0 2.4 0.2 1.0 0.0 1.4 0.4 1.9 1.9 18.7 2.3 2.1 0.0 1.8 0.3 0.0 1.0 5.7 288.7 32.1 20.3 6.1 16.3 4.4 4.1 23.4 5.0 CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 279.2;neutrophil: 296.6" "Group enriched" "Detected in all" 7 "granulocytes: 296.6;monocytes: 84.2" "Cell line enhanced" "Detected in many" "HHSteC: 223.9;Karpas-707: 337.4;U-266/84: 259.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: AB_2668242, HPA026861: AB_1846192" "unprognostic (3.14e-2)" "unprognostic (2.94e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (1.40e-2)" "unprognostic (8.34e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (3.17e-2)" "unprognostic (2.61e-2)" "prognostic unfavorable (5.07e-4)" "prognostic unfavorable (5.02e-5)" "unprognostic (1.15e-1)" "unprognostic (1.71e-2)" "unprognostic (1.72e-2)" 38.9 37.8 24.0 23.7 27.7 63.8 34.1 23.1 28.4 61.1 36.8 33.3 24.3 26.7 36.1 20.1 22.0 53.8 56.2 24.7 26.9 51.5 66.9 39.3 22.2 18.4 17.3 22.9 84.8 73.3 32.3 27.4 17.7 41.0 33.2 48.2 77.1 42.3 53.0 13.5 25.6 33.5 17.2 28.7 47.5 29.6 27.3 12.2 84.4 35.3 24.2 29.9 9.7 22.9 13.9 47.7 10.9 24.4 173.6 59.3 15.5 30.0 56.4 17.2 26.1 14.4 23.5 20.8 99.5 97.5 33.6 18.7 9.5 25.1 14.4 55.5 14.2 28.1 58.4 12.8 223.9 39.6 84.2 49.5 59.8 35.6 34.4 143.3 65.2 0.8 47.7 337.4 55.1 17.9 0.2 19.3 6.5 54.4 11.8 6.2 17.4 84.8 36.1 10.1 14.0 21.5 35.3 19.5 151.4 35.0 31.0 85.1 65.7 50.8 11.1 38.9 20.4 65.2 259.6 13.0 95.6 77.2 41.0 220.8 59.4 279.2 26.8 50.7 22.5 18.1 16.6 20.7 27.6 13.4 13.9 20.0 296.6 25.7 84.2 4.7 23.0 32.9 24.0 27.7 23.1 28.4 24.7 26.9 18.4 17.3 17.7 17.2 27.3 22.9 92.3 115.4 118.1 0.0 44.6 15.4 30.3 99.2 13.6 68.7 40.2 40.1 14.4 50.1 136.5 88.3 93.8 29.3 42.9 43.7 5.9 60.9 136.2 49.6 41.0 60.1 16.7 25.2 0.0 145.3 23.2 78.6 33.1 62.3 39.1 30.0 76.1 96.1 51.0 85.8 0.0 28.8 114.0 55.9 25.2 216.1 56.5 71.7 48.0 0.0 89.8 72.6 38.1 0.0 0.0 67.6 45.1 116.6 180.8 42.6 29.5 36.7 123.8 128.0 52.6 80.2 48.1 43.3 41.1 11.8 16.6 24.6 41.8 70.0 16.2 21.8 CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.5" "Group enriched" "Detected in many" 4 "Extravillous trophoblasts: 81.2;Hofbauer cells: 117.4;Kupffer cells: 171.9;Macrophages: 74.2;monocytes: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 330.3;RPMI-8226: 158.5;U-266/70: 57.7;U-266/84: 183.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" 21.0 4.7 2.1 42.5 2.3 24.8 4.0 2.4 3.1 2.5 2.6 5.6 7.3 2.5 1.6 3.4 2.8 11.7 2.4 1.9 2.6 4.9 17.2 18.7 10.9 5.2 3.2 2.1 3.1 1.9 0.9 26.4 4.5 1.6 7.3 0.3 2.1 2.6 1.3 0.6 6.6 15.5 4.7 30.8 4.9 1.7 4.9 5.7 1.0 3.3 10.2 16.7 0.7 7.4 0.3 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.2 0.0 0.3 0.7 1.5 0.1 0.4 0.0 3.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 6.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 330.3 0.0 0.2 0.2 13.0 0.0 0.0 0.0 0.1 0.0 158.5 0.0 5.6 0.0 0.0 0.0 0.4 1.3 0.9 0.2 35.5 0.0 0.8 0.0 0.0 0.2 57.7 183.7 0.1 29.1 26.5 0.4 82.5 125.1 25.8 10.5 76.2 50.1 2.9 0.1 8.5 53.9 0.2 0.1 1.4 113.4 84.5 51.3 18.9 0.1 50.6 2.1 2.3 2.4 3.1 1.9 2.6 5.2 3.2 4.5 4.7 4.9 7.4 0.3 3.2 3.0 0.0 2.0 0.9 0.0 0.0 0.6 0.0 0.1 0.5 0.6 0.0 1.3 0.0 0.0 1.3 15.9 0.0 1.9 0.0 0.4 0.1 0.6 1.6 0.0 1.7 0.0 0.0 81.2 2.4 0.0 0.0 3.8 0.0 1.4 1.2 117.4 0.0 0.0 0.0 0.0 171.9 23.5 0.1 0.0 74.2 5.4 9.4 51.5 0.2 7.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 3.2 1.5 0.2 0.0 0.4 0.5 0.0 0.2 0.2 1.7 2.9 6.0 0.0 0.0 0.0 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD164 "DFNA66, MGC-24, MUC-24" ENSG00000135535 "CD164 molecule" Q04900 6 109366514-109382467 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010636 Uncertain "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA010636: AB_1078447" "unprognostic (1.23e-2)" "unprognostic (1.61e-2)" "unprognostic (3.89e-2)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-2)" "unprognostic (1.97e-3)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (8.88e-2)" "unprognostic (1.38e-1)" "unprognostic (7.11e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.01e-1)" "unprognostic (1.51e-1)" 260.9 123.6 43.6 119.1 53.6 213.9 211.2 57.4 69.5 151.0 68.9 264.8 252.0 117.0 161.9 95.0 124.8 159.3 91.8 40.6 57.7 298.1 256.8 121.9 137.8 65.3 56.1 126.4 124.1 219.2 89.5 190.1 64.1 146.1 270.5 36.4 303.8 112.7 96.0 89.2 277.6 116.1 52.3 121.0 272.8 113.6 50.7 132.0 360.4 91.7 122.9 154.2 76.0 70.7 130.0 73.0 34.6 242.9 503.0 496.6 235.7 230.8 304.0 213.7 308.0 148.1 194.9 105.7 218.0 261.5 198.0 125.4 136.9 152.7 315.4 220.1 144.5 177.8 72.0 173.9 294.9 209.5 399.0 384.6 279.7 211.3 186.5 270.3 196.9 86.9 178.9 279.9 287.8 141.1 191.5 251.2 52.9 273.1 119.6 126.3 109.0 135.1 292.2 180.5 40.2 80.9 144.6 184.0 348.6 168.0 167.7 265.0 205.6 138.8 99.1 199.5 188.6 96.3 147.4 121.2 244.0 242.8 147.2 349.0 192.3 167.0 166.8 198.6 175.0 126.2 135.2 155.1 189.7 111.0 138.0 150.1 128.5 255.2 197.5 214.1 192.9 413.8 43.6 53.6 57.4 69.5 40.6 57.7 65.3 56.1 64.1 52.3 50.7 70.7 76.5 163.5 78.9 22.5 168.1 200.1 180.2 149.6 128.7 33.8 251.1 123.3 70.9 174.5 153.5 281.4 25.0 244.9 372.7 600.0 93.9 178.8 103.8 111.9 109.2 89.2 166.5 92.8 22.1 136.8 407.2 176.3 175.8 151.2 128.6 76.7 98.2 177.4 311.9 33.7 16.4 427.3 215.7 360.4 223.9 97.3 158.8 237.3 247.3 38.4 147.1 113.3 266.8 15.6 83.1 177.6 430.0 182.1 173.6 230.3 425.5 348.0 351.2 44.4 124.9 110.0 138.1 160.5 184.4 143.0 231.0 674.5 165.9 87.7 285.0 334.7 CD177 "HNA2A, NB1, PRV1" ENSG00000204936 "CD177 molecule" 19 43353686-43363172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 285.9;intestine: 164.6" "Group enriched" "Detected in some" 5 "Distal enterocytes: 632.4;Paneth cells: 314.8" "Cancer enhanced" "Detected in many" "prostate cancer: 27.6" "Group enriched" "Detected in many" 4 "cerebellum: 3.6;cerebral cortex: 7.7;pons: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 8.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 98.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041820, HPA046601, HPA077640" Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA041820: AB_2677691, HPA046601: AB_2679716, HPA077640: " "unprognostic (4.32e-2)" "prognostic favorable (3.66e-4)" "unprognostic (1.04e-2)" "unprognostic (2.04e-3)" "unprognostic (1.61e-1)" "unprognostic (3.89e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (2.05e-1)" "unprognostic (1.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.90e-2)" "unprognostic (2.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.16e-1)" "unprognostic (5.01e-2)" "unprognostic (1.24e-1)" 4.8 0.4 0.1 7.2 0.3 285.9 1.3 3.6 7.7 6.0 3.7 155.2 0.3 0.4 0.2 2.2 2.3 0.2 2.2 0.3 0.1 1.9 2.6 20.6 0.2 0.3 1.0 0.3 1.1 0.0 2.9 1.6 2.3 64.8 164.6 0.1 1.8 0.2 0.7 0.4 0.7 3.0 0.3 64.4 1.4 0.2 0.4 1.4 0.7 0.8 10.4 2.1 5.4 0.5 2.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 1.3 0.6 0.6 0.0 0.0 0.1 2.4 0.6 1.7 0.2 0.1 0.0 1.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 1.2 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.4 1.2 0.0 0.2 0.0 0.0 98.0 1.4 0.3 0.7 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.3 2.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 1.2 0.0 0.7 0.0 0.1 0.3 3.6 7.7 0.3 0.1 0.3 1.0 2.3 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 632.4 0.0 0.5 0.4 0.2 0.1 0.0 8.4 3.6 0.0 0.2 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 87.2 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 314.8 0.0 0.1 29.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 28.0 0.2 CD209 "CDSIGN, CLEC4L, DC-SIGN, DC-SIGN1" ENSG00000090659 "CD209 molecule" Q9NNX6 19 7739993-7747564 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Endocytosis, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 34.2;placenta: 22.8" "Group enriched" "Detected in some" 4 "Kupffer cells: 15.6;Langerhans cells: 14.7;Macrophages: 12.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "classical monocyte: 1.4;intermediate monocyte: 1.4;myeloid DC: 1.2" "Group enriched" "Detected in many" 4 "dendritic cells: 1.2;monocytes: 1.4" "Cell line enriched" "Detected in single" 14 "THP-1: 3.3" "CAB032436, CAB033831" Supported "Intracellular and membrane" NA NA 3100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB032436: AB_639039, CAB033831: AB_1121347" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (5.36e-3)" "unprognostic (1.25e-1)" "unprognostic (4.43e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-2)" "unprognostic (3.83e-2)" "unprognostic (2.10e-2)" "unprognostic (1.24e-1)" "unprognostic (9.65e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (6.17e-2)" "unprognostic (1.09e-1)" 34.2 3.9 0.3 8.6 0.6 0.4 4.4 1.3 3.0 4.0 5.7 10.5 14.3 1.4 1.0 4.8 2.5 8.6 4.5 0.3 0.7 2.1 3.3 4.9 18.1 1.0 0.6 1.0 1.0 0.8 0.7 22.8 0.8 0.8 13.9 0.1 2.1 1.9 0.9 1.4 19.3 10.6 0.9 2.4 4.1 2.1 0.6 5.4 1.4 1.5 2.3 20.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.4 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.4 0.3 0.6 1.3 3.0 0.3 0.7 1.0 0.6 0.8 0.9 0.6 0.8 0.3 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 15.6 14.7 0.3 0.0 12.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.1 CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1572.7;Distal tubular cells: 1590.6;Exocrine glandular cells: 3454.1;Glandular and luminal cells: 1441.8;Pancreatic endocrine cells: 1694.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Cell line enhanced" "Detected in many" "NTERA-2: 989.4;RPTEC TERT1: 4702.6;RT4: 931.5;SK-BR-3: 1352.5" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" 7.1 61.9 23.3 139.1 28.8 704.5 468.1 6.4 30.0 288.0 36.7 1071.8 89.0 181.5 229.6 1456.5 242.9 874.3 5.1 45.0 29.2 775.6 30.2 61.6 77.8 26.6 26.0 2.2 1383.4 2.5 12.5 151.7 17.2 148.8 740.8 2.6 952.4 546.9 1.4 77.2 69.8 117.7 19.5 29.6 601.7 4.9 38.6 15.2 1630.2 1.1 445.0 168.9 468.3 50.7 363.2 225.2 3.9 28.6 0.7 0.3 405.8 0.4 2.6 2.0 1.2 3.3 1.9 35.4 106.0 0.1 14.6 730.6 124.1 275.6 1.5 1.0 1.7 1.0 254.2 16.3 0.2 5.1 1.8 2.1 316.1 3.6 18.0 16.9 1.6 1.4 8.3 0.8 6.6 465.6 2.4 2.6 989.4 800.1 85.6 846.8 0.5 3.5 4702.6 931.5 612.4 448.7 250.0 1352.5 1.4 437.1 635.6 2.1 1.6 0.8 4.0 3.1 11.8 1.0 2.0 475.2 5.0 2.9 1.6 0.3 0.1 86.2 0.0 0.0 0.0 61.1 0.0 0.0 0.0 39.7 0.0 0.1 2.1 0.1 0.3 0.1 0.0 2.0 23.3 28.8 6.4 30.0 45.0 29.2 26.6 26.0 17.2 19.5 38.6 50.7 10.2 157.0 83.5 0.7 157.5 0.0 70.4 0.0 7.4 5.8 1109.4 325.4 1.5 1112.3 98.4 1302.1 2.1 749.2 13.7 1572.7 1590.6 1274.1 22.5 1237.6 254.2 38.6 575.4 5.3 0.6 3454.1 885.0 29.9 567.2 1441.8 10.8 0.6 97.5 9.7 70.8 0.0 5.7 463.6 0.0 7.6 0.0 53.4 10.2 17.6 0.0 1.0 32.6 1.0 0.0 0.0 0.1 1694.3 865.2 2.2 1.0 810.2 12.3 538.5 376.8 0.7 6.6 2.9 18.1 0.6 7.2 587.7 0.0 558.3 28.1 0.0 932.8 1043.7 CD247 "CD3H, CD3Q, CD3Z" ENSG00000198821 "CD247 molecule" P20963 1 167430640-167518610 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 49.0;lymphoid tissue: 179.4" "Group enriched" "Detected in many" 9 "dendritic cells: 492.1;NK-cells: 727.1;T-cells: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "gdT-cell: 376.4;MAIT T-cell: 208.9;memory CD4 T-cell: 190.0;memory CD8 T-cell: 219.7;naive CD4 T-cell: 237.8;naive CD8 T-cell: 195.1;NK-cell: 225.3;T-reg: 254.5" "Group enriched" "Detected in all" 32 "NK-cells: 225.3;T-cells: 376.4" "Group enriched" "Detected in some" 25 "HDLM-2: 155.9;JURKAT: 113.1;MOLT-4: 167.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004651, HPA008750" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB004651: AB_425347, HPA008750: AB_1857863" "prognostic favorable (9.12e-4)" "unprognostic (3.21e-3)" "unprognostic (7.09e-3)" "prognostic favorable (8.63e-6)" "unprognostic (1.99e-2)" "prognostic favorable (3.98e-4)" "unprognostic (1.79e-2)" "unprognostic (1.11e-2)" "unprognostic (5.46e-3)" "unprognostic (9.73e-3)" "unprognostic (1.33e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (1.60e-1)" "unprognostic (5.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.94e-3)" 3.2 1.7 2.3 25.3 2.3 49.0 1.9 2.2 2.5 1.9 1.9 4.3 7.1 2.3 3.1 2.1 1.8 5.5 1.3 2.3 2.3 2.0 5.4 10.9 57.7 2.3 2.2 0.8 0.8 0.5 0.8 1.4 2.2 1.8 4.6 0.2 2.4 1.6 1.4 1.1 14.3 1.5 2.1 40.2 7.0 0.4 2.9 179.4 2.5 0.9 36.4 7.3 1.9 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 155.9 0.3 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 113.1 0.0 0.1 0.0 0.0 167.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 8.3 1.0 0.4 376.4 1.4 208.9 9.3 190.0 219.7 1.5 4.9 237.8 195.1 8.7 225.3 1.2 2.8 254.5 231.2 2.3 2.3 2.2 2.5 2.3 2.3 2.3 2.2 2.2 2.1 2.9 2.5 3.4 3.2 16.0 3.3 8.2 1.5 0.1 0.0 0.6 0.4 3.5 3.2 0.6 1.5 1.3 0.0 0.0 0.1 492.1 0.4 0.0 0.5 0.2 0.7 0.8 1.8 0.0 14.7 8.8 0.0 0.1 2.2 6.1 1.1 6.3 0.4 7.1 1.4 0.3 3.3 9.4 0.5 0.0 7.8 1.4 0.2 0.0 5.9 3.6 14.0 7.6 0.1 727.1 0.5 3.7 0.0 1.2 0.0 51.9 0.1 0.2 1.3 2.2 0.2 0.0 0.9 1.2 0.1 2.5 1.4 0.6 0.1 247.2 0.0 0.1 0.1 CD52 "CDW52, EDDM5, HE5" ENSG00000169442 "CD52 molecule" P31358 1 26317958-26320523 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted membrane proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "epididymis: 36173.0" "Cell type enhanced" "Detected in many" "B-cells: 1861.9;granulocytes: 568.6;Hofbauer cells: 562.6;Langerhans cells: 674.3;Macrophages: 690.5;monocytes: 814.2;NK-cells: 602.5;T-cells: 1300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Daudi: 708.6;REH: 1042.2;U-266/84: 1087.0;U-698: 1159.2" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 16: U-266 - Nucleosome" "Cluster 57: B-cells - Immune response" "prognostic favorable (1.85e-5)" "unprognostic (3.28e-3)" "unprognostic (1.93e-2)" "prognostic favorable (2.06e-4)" "unprognostic (4.18e-2)" "prognostic favorable (4.45e-4)" "unprognostic (9.11e-2)" "unprognostic (2.98e-2)" "unprognostic (7.73e-3)" "unprognostic (6.27e-2)" "unprognostic (4.58e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.64e-1)" "unprognostic (6.14e-2)" "unprognostic (7.95e-2)" "unprognostic (1.26e-1)" 62.1 10.2 10.2 297.8 13.5 266.9 59.5 9.6 38.5 26.1 12.6 68.6 41.7 21.3 36173.0 35.0 18.4 89.2 18.0 10.3 10.0 18.7 55.0 449.2 1082.0 11.3 10.0 9.6 8.2 5.4 6.1 16.9 10.5 19.2 96.9 0.2 37.6 104.2 9.4 27.9 294.7 47.4 10.1 646.5 87.2 4.7 16.5 1051.6 24.9 13.8 1256.4 134.9 13.1 10.5 2.0 0.0 0.3 0.0 0.0 1.4 14.3 0.1 1.0 0.1 0.0 0.3 0.6 708.6 1.4 0.0 0.3 0.1 0.0 0.2 0.0 0.5 0.2 34.8 0.0 1.4 0.0 7.5 106.4 0.0 0.0 0.2 0.0 0.7 0.0 44.9 23.7 1.0 0.0 4.6 8.5 62.9 3.0 0.5 0.0 1042.2 0.9 16.6 0.0 0.0 2.1 9.3 0.4 1.1 1.3 9.2 0.3 12.5 1.6 0.0 2.7 0.7 1.2 2.9 1087.0 1159.2 0.1 17.8 0.1 599.3 4558.9 9769.3 6605.8 7389.3 5319.0 10570.4 8177.1 6530.7 3180.2 10064.7 5495.2 5664.3 334.5 3732.1 6667.9 1034.9 11684.0 22571.2 10.2 13.5 9.6 38.5 10.3 10.0 11.3 10.0 10.5 10.1 16.5 10.5 9.5 67.3 194.6 0.0 1861.9 45.4 0.8 0.2 3.4 0.0 8.4 5.8 6.2 14.3 50.1 49.7 0.0 4.7 415.9 1.9 0.0 1.3 0.8 3.9 2.6 29.5 0.0 60.6 0.3 0.2 5.8 18.1 29.6 7.1 568.6 0.0 17.5 3.6 562.6 0.0 0.1 2.3 0.0 262.6 674.3 1.4 0.0 690.5 106.7 1.9 814.2 0.0 602.5 0.0 0.1 0.2 2.8 0.0 133.7 3.1 0.7 11.5 17.5 0.0 0.0 7.3 9.1 0.3 0.5 3.2 31.4 5.6 1300.0 0.0 2.7 1.1 CD6 Tp120 ENSG00000013725 "CD6 molecule" P30203 11 60971680-61020377 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.6;lymphoid tissue: 43.1" "Cell type enhanced" "Detected in many" "dendritic cells: 25.7;NK-cells: 49.4;Plasma cells: 18.5;T-cells: 107.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 33 "gdT-cell: 27.7;MAIT T-cell: 24.7;memory CD4 T-cell: 51.4;memory CD8 T-cell: 48.4;naive CD4 T-cell: 34.4;naive CD8 T-cell: 25.2;T-reg: 25.5" "Lineage enriched" "Detected in many" 51 "T-cells: 51.4" "Group enriched" "Detected in some" 12 "JURKAT: 10.2;MOLT-4: 39.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002489, CAB016252" Enhanced "Secreted to blood" NA NA 5270000 160000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB002489: AB_563605, CAB016252: AB_631163" "prognostic favorable (1.95e-4)" "prognostic favorable (1.57e-5)" "unprognostic (4.47e-2)" "prognostic favorable (2.41e-4)" "unprognostic (2.06e-2)" "prognostic favorable (5.10e-6)" "unprognostic (8.45e-3)" "unprognostic (8.21e-3)" "unprognostic (2.87e-3)" "unprognostic (5.32e-3)" "unprognostic (2.07e-1)" "unprognostic (5.35e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "unprognostic (6.19e-2)" "unprognostic (5.96e-2)" 1.4 0.9 1.5 21.9 0.9 11.3 1.2 0.5 1.1 1.3 0.7 3.2 4.0 0.9 0.7 1.8 1.4 3.9 0.5 0.6 1.7 1.0 1.4 6.6 43.1 1.5 2.0 0.9 0.6 0.2 0.4 0.3 1.7 1.1 3.1 0.2 3.2 0.4 0.8 1.3 13.6 0.7 0.9 18.0 6.6 0.7 2.5 39.6 1.4 0.3 29.0 4.8 1.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.2 0.0 0.0 0.0 39.2 0.1 0.2 0.2 0.1 0.1 0.0 0.8 0.0 0.1 0.1 0.2 0.0 0.4 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.7 0.0 24.7 1.0 51.4 48.4 0.3 0.9 34.4 25.2 0.7 0.2 0.0 0.0 25.5 13.8 1.5 0.9 0.5 1.1 0.6 1.7 1.5 2.0 1.7 0.9 2.5 0.9 3.2 0.0 2.5 0.3 10.8 2.0 0.2 0.1 0.0 1.4 0.9 0.8 2.6 1.5 0.1 0.0 0.0 0.2 25.7 0.2 0.0 0.2 0.9 0.4 0.3 1.2 0.0 0.0 0.8 0.6 0.2 1.5 8.2 0.3 0.0 0.1 2.5 0.8 2.0 1.7 0.9 0.0 0.0 1.9 4.4 0.4 0.3 3.4 3.6 1.0 2.4 0.0 49.4 0.0 0.2 0.7 0.2 0.0 18.5 0.0 0.1 0.2 0.1 0.2 0.0 1.0 0.9 0.4 0.9 1.0 1.4 0.3 107.3 0.7 0.5 0.4 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD7 "GP40, LEU-9, Tp40, TP41" ENSG00000173762 "CD7 molecule" P09564 17 82314868-82317608 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.6;lymphoid tissue: 53.7" "Group enriched" "Detected in many" 9 "dendritic cells: 625.0;NK-cells: 1299.7;T-cells: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 231.5" "Group enriched" "Detected in many" 22 "NK-cells: 231.5;T-cells: 71.5" "Cell line enhanced" "Detected in some" "Hep G2: 52.0;JURKAT: 26.7;MOLT-4: 119.2" "Region enhanced" "Detected in some" "cerebral cortex: 3.2" "Not detected" "Not detected" "CAB002594, HPA039079" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002594: , HPA039079: AB_2676337" "unprognostic (3.14e-3)" "prognostic favorable (5.51e-4)" "unprognostic (1.89e-2)" "prognostic favorable (2.03e-5)" "unprognostic (7.69e-3)" "unprognostic (1.09e-3)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "prognostic favorable (2.69e-4)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-1)" "prognostic unfavorable (7.75e-11)" "unprognostic (4.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-3)" 8.2 1.3 0.7 32.9 0.8 28.6 2.6 0.8 1.3 2.5 0.9 7.3 12.4 3.0 0.4 3.9 3.9 3.2 1.8 0.6 1.1 7.1 7.7 17.1 36.8 1.4 0.8 0.8 1.2 0.1 1.4 3.3 1.0 4.4 1.9 0.0 3.1 1.0 0.8 1.7 21.1 1.1 1.2 53.7 8.1 0.6 1.1 48.8 3.5 0.1 14.8 3.9 3.9 1.2 0.0 0.0 0.0 0.0 0.1 0.4 12.9 0.0 0.2 0.1 0.2 0.6 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.7 52.0 0.6 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 26.7 0.1 0.0 0.1 0.0 119.2 0.0 0.0 0.0 0.2 0.1 0.1 2.3 0.2 0.0 0.4 0.3 1.8 1.1 0.0 0.3 0.0 0.0 0.0 0.3 0.3 1.0 0.0 1.2 0.2 0.0 0.2 0.0 0.0 0.5 0.4 0.5 66.6 0.2 57.6 0.4 29.8 49.0 0.3 0.2 69.4 71.5 2.3 231.5 0.6 6.9 28.7 30.9 0.7 0.8 0.8 1.3 0.6 1.1 1.4 0.8 1.0 1.2 1.1 1.2 5.3 0.0 0.0 0.0 12.1 7.5 0.6 0.1 1.8 0.0 4.2 3.7 0.5 4.3 0.3 0.0 0.0 0.7 625.0 9.4 0.0 1.3 0.1 2.8 2.0 4.5 0.0 47.7 0.0 0.5 10.3 12.4 43.8 5.3 8.2 0.0 16.8 3.3 3.6 1.7 0.0 1.5 0.0 18.5 8.8 0.0 0.0 19.2 12.4 0.0 11.6 0.0 1299.7 0.0 0.0 0.1 5.8 0.0 82.7 3.8 8.1 1.4 0.5 0.0 0.0 0.5 3.9 0.0 1.3 1.0 4.4 1.9 527.4 0.0 2.1 3.8 CD96 TACTILE ENSG00000153283 "CD96 molecule" P40200 3 111292719-111665750 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.8" "Group enriched" "Detected in many" 4 "dendritic cells: 96.8;NK-cells: 58.7;T-cells: 199.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 74.0;MAIT T-cell: 117.2;memory CD4 T-cell: 67.0;memory CD8 T-cell: 85.3;naive CD4 T-cell: 68.7;naive CD8 T-cell: 81.8;NK-cell: 79.5;T-reg: 47.4" "Group enriched" "Detected in many" 5 "NK-cells: 79.5;T-cells: 117.2" "Cell line enhanced" "Detected in some" "HEL: 15.9;JURKAT: 18.2;MOLT-4: 68.7;RT4: 58.2;U-937: 59.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066754 Enhanced NA NA 85000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA066754: AB_2685714" "unprognostic (1.06e-3)" "unprognostic (3.95e-3)" "unprognostic (4.16e-3)" "unprognostic (1.91e-5)" "unprognostic (4.72e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.12e-2)" "unprognostic (3.48e-2)" "unprognostic (6.06e-2)" "unprognostic (4.84e-3)" "unprognostic (2.44e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (2.02e-6)" "unprognostic (3.12e-1)" "unprognostic (4.42e-2)" "unprognostic (3.90e-2)" "prognostic favorable (5.23e-5)" 5.2 1.7 0.7 12.2 0.8 16.0 2.8 1.2 1.0 3.1 1.8 5.0 6.0 2.6 0.9 1.8 1.9 5.8 0.8 0.8 0.8 1.6 3.7 8.3 26.9 1.8 0.7 0.9 0.4 0.2 0.7 1.0 1.2 2.1 5.9 0.1 2.7 1.1 0.4 1.0 10.1 1.4 0.7 12.8 6.8 0.8 1.2 61.8 3.9 0.1 20.2 11.8 2.6 2.2 0.1 0.0 0.2 0.1 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.3 1.6 0.3 0.3 0.0 0.0 0.7 0.1 0.1 0.0 0.2 0.0 15.9 0.2 0.2 0.0 0.8 1.3 0.0 0.0 0.1 0.1 1.2 0.0 18.2 0.3 2.0 0.0 0.0 68.7 0.2 0.6 0.0 0.0 0.1 1.9 0.5 0.6 58.2 0.1 0.0 0.2 0.9 0.1 0.3 0.3 0.2 0.0 0.3 1.1 0.3 0.1 5.6 1.9 0.0 0.3 59.0 12.2 2.3 0.5 15.6 74.0 0.3 117.2 10.8 67.0 85.3 0.3 18.8 68.7 81.8 2.7 79.5 0.7 0.5 47.4 46.4 0.7 0.8 1.2 1.0 0.8 0.8 1.8 0.7 1.2 0.7 1.2 2.2 1.5 19.2 19.0 0.0 12.5 3.2 0.8 0.1 1.2 1.6 1.6 1.4 1.0 0.0 9.3 1.8 0.0 0.6 96.8 0.8 0.0 0.1 0.8 2.1 0.8 3.0 0.0 9.3 0.7 0.0 0.2 4.3 8.6 1.6 16.4 0.4 2.2 0.9 0.2 0.0 0.4 0.7 0.0 5.0 6.7 1.1 0.3 6.7 3.6 6.5 2.9 0.5 58.7 0.0 0.1 0.0 1.3 0.0 29.6 0.3 0.0 0.4 1.7 2.1 0.0 0.8 1.0 0.4 0.7 0.6 3.1 1.9 199.9 0.2 0.5 0.6 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDK5R2 "NCK5AI, P39, p39nck5ai" ENSG00000171450 "Cyclin dependent kinase 5 regulatory subunit 2" Q13319 2 218959666-218962155 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 52.2;pituitary gland: 35.2;retina: 26.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 78.8;Cone photoreceptor cells: 20.9;Enteroendocrine cells: 22.8;Excitatory neurons: 17.7;Horizontal cells: 15.2;Rod photoreceptor cells: 50.9" "Cancer enhanced" "Detected in some" "glioma: 3.9;pancreatic cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 18.4;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.96e-1)" "unprognostic (6.53e-2)" "unprognostic (3.85e-5)" "unprognostic (1.73e-6)" "unprognostic (3.67e-2)" "unprognostic (2.83e-4)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.71e-3)" "unprognostic (3.53e-3)" "unprognostic (2.34e-10)" "unprognostic (1.54e-1)" "unprognostic (1.64e-4)" "unprognostic (6.46e-2)" 0.0 3.9 17.0 0.3 21.5 0.0 0.0 0.0 52.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.2 17.4 0.0 0.0 0.0 0.0 7.1 3.6 0.0 1.0 0.0 35.2 0.0 10.7 0.0 0.1 26.3 0.0 0.0 0.0 0.0 0.4 0.1 1.4 0.0 0.9 0.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 20.0 0.4 0.4 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 2.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 18.4 13.3 0.7 0.0 0.1 0.4 0.0 0.0 0.0 0.2 1.3 0.0 0.3 0.0 0.0 0.0 0.6 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 21.5 0.0 52.2 20.2 17.4 7.1 3.6 10.7 1.4 15.6 20.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 78.8 0.0 0.0 0.5 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 22.8 0.0 17.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.2 11.9 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 8.1 0.0 2.0 2.6 0.2 1.2 0.0 0.0 0.1 0.1 0.0 0.0 50.9 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50326265-50416461 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.4;Excitatory neurons: 46.2;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA059605: AB_2684080, HPA065919: AB_2685578" "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 13.5 3.6 3.4 4.9 4.4 3.6 3.5 1.4 9.0 13.9 3.7 8.8 13.2 13.9 3.2 5.2 15.4 5.2 2.3 5.5 2.3 19.4 1.6 6.5 6.5 2.0 2.1 13.8 1.3 1.2 0.6 6.5 2.9 5.9 6.6 20.2 2.8 9.0 7.1 13.5 6.9 8.5 2.9 7.0 4.9 2.0 1.8 1.9 7.9 1.0 2.6 6.9 6.6 8.1 7.7 4.9 3.5 4.3 5.3 6.1 2.3 2.2 3.2 1.9 2.0 4.0 5.9 6.1 2.8 3.2 3.2 5.9 0.8 0.3 1.9 8.9 3.1 12.2 4.6 3.9 6.2 9.7 5.3 1.5 3.0 3.2 8.0 2.4 6.7 10.3 3.3 4.8 1.1 2.5 2.8 4.7 1.9 2.6 3.9 3.3 3.8 3.1 5.3 6.6 4.6 3.4 4.2 18.3 2.1 1.3 2.4 6.2 4.0 6.7 4.1 7.1 5.0 2.4 1.8 2.9 1.7 8.7 7.6 3.2 1.4 2.6 3.5 1.4 3.1 2.6 2.3 3.2 0.8 3.0 1.9 1.9 0.7 2.3 0.2 0.8 2.4 1.3 3.4 4.4 1.4 9.0 5.5 2.3 2.0 2.1 2.9 2.9 1.8 8.1 3.2 19.2 9.9 6.5 3.0 3.1 4.1 0.2 3.4 0.7 0.4 0.5 0.5 0.0 2.6 11.0 0.0 0.1 2.3 7.2 5.9 1.4 0.4 23.4 9.6 3.3 1.8 6.1 46.2 1.8 0.1 7.6 1.1 4.9 1.3 3.2 6.4 0.3 0.4 0.0 20.6 2.1 2.0 0.9 1.5 1.5 9.0 1.5 0.0 7.5 0.8 0.9 2.1 46.8 25.4 1.9 4.8 3.4 0.2 3.1 4.9 8.0 20.4 0.7 0.0 4.0 4.6 0.0 0.3 4.7 2.7 0.3 4.2 3.6 5.2 2.2 CDS1 ENSG00000163624 "CDP-diacylglycerol synthase 1" Q92903 4 84583127-84651334 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 129.8;Respiratory ciliated cells: 210.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 46.1;hTCEpi: 56.9;OE19: 45.5;SK-BR-3: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036187, HPA064546" Enhanced NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "HPA036187: AB_10601797, HPA064546: AB_2732714" "unprognostic (8.74e-2)" "unprognostic (7.11e-2)" "prognostic favorable (5.22e-4)" "unprognostic (2.73e-3)" "unprognostic (1.45e-2)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "unprognostic (3.11e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.16e-1)" "unprognostic (6.67e-2)" "prognostic favorable (0.00e+0)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-1)" "unprognostic (2.06e-1)" 1.0 6.1 8.8 1.5 9.5 0.6 10.2 11.1 17.8 6.3 19.0 20.0 40.2 3.0 29.0 20.1 32.2 8.0 0.5 8.9 11.6 14.9 0.5 10.7 0.6 15.9 11.2 5.2 4.7 28.3 4.8 7.2 16.6 9.4 21.3 22.4 12.5 4.7 0.1 15.4 34.4 1.2 9.9 1.6 18.4 7.4 14.7 3.5 30.4 0.1 5.1 6.7 9.2 8.2 26.5 0.6 1.5 0.3 0.1 0.0 26.5 0.0 0.4 0.6 0.5 11.2 46.1 0.0 2.0 0.0 5.4 27.2 8.5 23.2 0.3 1.8 12.6 0.0 3.8 2.7 0.0 0.8 1.8 0.2 56.9 0.0 8.2 1.0 0.0 1.5 0.1 0.0 0.1 18.8 0.2 0.1 3.8 45.5 1.8 0.1 0.0 5.7 12.7 20.0 10.6 0.2 2.9 62.1 0.1 4.9 19.0 0.5 0.0 0.0 1.4 2.8 3.5 0.0 0.0 0.0 2.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 9.5 11.1 17.8 8.9 11.6 15.9 11.2 16.6 9.9 14.7 8.2 0.8 16.0 42.3 33.3 0.4 29.1 27.7 26.4 26.7 16.7 26.6 13.6 1.4 24.3 39.5 40.5 10.4 60.0 0.4 63.0 3.9 26.4 12.1 129.8 3.8 3.3 22.3 0.0 43.1 22.8 12.1 3.5 41.3 45.2 0.0 15.4 1.4 0.7 12.7 21.9 64.6 53.9 48.8 3.5 13.9 4.5 0.6 3.5 0.0 9.4 1.2 29.0 0.0 3.5 2.4 40.8 30.4 0.4 0.1 30.8 80.0 15.9 210.7 32.0 0.0 1.2 4.3 13.1 6.6 41.1 54.1 57.3 1.6 4.8 51.6 38.3 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CELF3 "BRUNOL1, CAGH4, ERDA4, MGC57297, TNRC4" ENSG00000159409 "CUGBP Elav-like family member 3" Q5SZQ8 1 151700058-151716803 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.7;pituitary gland: 109.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 101.4;Cone photoreceptor cells: 39.6;Enteroendocrine cells: 52.8;Excitatory neurons: 21.1;Horizontal cells: 20.2;Inhibitory neurons: 20.4" "Group enriched" "Detected in many" 5 "glioma: 4.4;pancreatic cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 42.1;SH-SY5Y: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006292 Uncertain Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA006292: AB_10602250" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (7.67e-2)" "unprognostic (1.96e-1)" "unprognostic (1.75e-1)" "unprognostic (6.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.02e-2)" "unprognostic (3.12e-1)" "unprognostic (3.48e-3)" "unprognostic (3.49e-3)" "unprognostic (6.90e-2)" "unprognostic (1.82e-8)" "unprognostic (8.50e-2)" "unprognostic (9.01e-2)" "unprognostic (2.41e-1)" "unprognostic (3.05e-2)" 0.1 11.2 41.9 0.2 41.1 0.3 0.0 22.1 70.7 0.0 0.0 2.1 3.0 0.0 0.0 0.0 0.8 0.0 0.1 48.5 37.5 0.1 0.0 0.1 0.0 8.6 16.4 0.0 6.1 0.0 109.0 0.1 10.9 0.1 0.7 23.6 0.0 0.0 0.0 0.1 2.1 0.2 5.2 0.0 4.9 3.1 28.5 0.0 0.1 0.0 0.0 0.1 0.2 20.5 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 42.1 29.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.9 41.1 22.1 70.7 48.5 37.5 8.6 16.4 10.9 5.2 28.5 20.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 101.4 0.0 0.0 0.9 0.0 0.0 0.0 39.6 0.1 0.0 0.3 0.0 0.0 13.1 0.3 0.0 0.0 52.8 0.0 21.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 20.2 20.4 1.5 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 6.0 0.7 0.1 0.1 0.0 0.0 0.1 0.0 0.8 0.0 5.5 0.0 0.0 0.1 2.1 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.8" "Cell type enhanced" "Detected in many" "Horizontal cells: 97.6;Oligodendrocytes: 48.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 13.3;basal ganglia: 21.6;cerebral cortex: 44.6;hippocampal formation: 50.8;white matter: 26.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.9;HaCaT: 48.4;MCF7: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" 0.9 1.4 13.3 0.5 21.6 0.3 4.1 0.1 44.6 5.6 0.0 2.9 0.8 2.2 3.1 13.9 16.1 1.1 5.2 50.8 0.0 4.7 0.6 1.1 0.7 4.1 0.6 0.6 3.8 6.0 2.9 0.9 1.0 3.0 0.7 5.7 5.6 7.9 8.9 24.7 1.1 1.6 0.6 0.4 2.0 9.4 1.5 1.2 9.1 4.0 2.4 1.9 9.4 26.6 14.0 12.8 47.9 8.9 0.1 0.0 13.0 1.6 1.1 2.9 0.8 2.0 0.4 2.5 10.9 1.0 2.2 48.4 12.5 7.8 1.5 0.3 5.3 1.1 11.8 2.8 1.0 0.8 6.2 0.2 18.5 1.2 0.8 10.8 0.5 7.7 8.5 0.6 0.0 56.6 1.4 0.7 15.7 1.6 2.5 12.8 4.4 0.7 10.3 4.7 19.5 9.2 7.6 16.2 10.1 11.3 15.3 3.1 0.0 0.0 8.5 0.8 12.4 3.2 1.0 0.7 2.6 1.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 21.6 0.1 44.6 50.8 0.0 4.1 0.6 1.0 0.6 1.5 26.6 0.9 9.6 5.0 15.0 0.2 15.7 5.1 19.7 9.6 13.2 16.4 16.3 13.5 2.8 11.3 18.4 4.2 2.2 1.9 1.3 1.9 2.6 5.1 12.8 1.4 1.5 1.8 0.0 34.0 0.4 1.3 1.2 2.6 17.7 1.3 5.5 0.4 7.1 1.1 97.6 27.7 0.9 2.0 0.8 3.4 9.3 3.4 0.9 10.6 5.6 1.0 29.9 3.1 24.6 48.1 1.5 0.5 19.2 0.4 4.3 0.2 3.1 8.4 5.2 6.6 5.0 4.9 1.6 6.8 31.0 22.9 0.5 1.5 0.0 2.0 6.9 CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603195-214664571 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.8;lymphoid tissue: 33.0" "Cell type enhanced" "Detected in many" "Early spermatids: 84.4;Erythroid cells: 268.7;Extravillous trophoblasts: 78.8;Granulosa cells: 165.8;Spermatocytes: 107.5;Spermatogonia: 107.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB070134: AB_2229328, HPA052382: AB_2681808, HPA064308: AB_2732711" "unprognostic (2.80e-1)" "unprognostic (2.16e-1)" "unprognostic (2.65e-1)" "unprognostic (5.30e-2)" "unprognostic (1.73e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (2.29e-5)" "unprognostic (1.13e-2)" "unprognostic (2.58e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.58e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.92e-2)" "unprognostic (1.71e-1)" "unprognostic (1.89e-2)" "unprognostic (4.12e-1)" 0.8 1.1 0.1 4.4 0.1 28.8 1.8 0.0 0.3 1.3 0.5 5.8 6.1 1.8 0.1 8.6 0.6 0.7 0.4 0.3 0.0 0.4 0.9 0.9 8.5 0.3 0.5 0.7 0.3 0.2 0.1 3.1 0.3 0.5 5.7 1.0 1.4 0.1 0.2 6.2 4.3 2.5 0.2 2.4 2.6 10.5 0.5 33.0 0.4 0.6 10.0 1.4 2.6 0.3 123.7 68.4 144.3 75.8 5.4 7.2 56.3 74.6 30.3 43.9 42.8 54.6 74.1 116.3 43.1 41.7 39.8 74.7 89.9 49.2 74.1 102.6 56.6 96.0 111.4 78.6 0.8 137.0 50.5 2.7 3.8 63.3 72.3 12.7 46.9 52.6 88.4 68.0 79.4 47.0 81.5 54.3 127.9 36.8 30.0 85.7 203.7 38.6 43.2 30.3 67.4 91.2 100.7 66.2 38.9 76.2 79.1 51.9 61.7 78.9 92.2 66.2 155.9 51.6 60.7 108.7 34.4 96.7 71.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.3 0.0 0.3 0.5 0.3 0.2 0.5 0.3 3.0 0.0 3.1 0.0 11.5 9.3 2.8 11.2 3.4 4.7 10.0 6.7 1.9 1.5 9.9 0.0 0.0 53.3 10.8 19.1 0.0 2.0 84.4 30.1 19.3 12.4 0.0 268.7 1.3 0.4 78.8 19.0 32.1 25.2 1.3 165.8 8.9 2.6 32.2 1.7 0.8 20.1 14.2 16.6 6.6 19.8 1.2 16.2 1.8 1.0 0.7 1.4 5.2 0.0 0.1 0.5 1.1 3.0 25.9 2.3 2.1 0.1 16.7 3.1 0.0 8.3 23.9 107.5 107.1 44.6 5.5 5.1 23.3 11.7 41.3 3.7 CENPS "APITD1, CENP-S, FAAP16, MHF1" ENSG00000175279 "Centromere protein S" Q8N2Z9 1 10430433-10442808 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.7;Distal tubular cells: 37.2;Proximal tubular cells: 86.1;Respiratory ciliated cells: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 32: U-937 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.64e-1)" "prognostic favorable (1.24e-4)" "unprognostic (3.06e-3)" "unprognostic (2.21e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (4.72e-3)" "unprognostic (3.79e-1)" "unprognostic (1.26e-3)" "unprognostic (2.95e-2)" "unprognostic (4.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.04e-3)" "unprognostic (4.23e-2)" "unprognostic (4.66e-2)" "unprognostic (1.87e-1)" "unprognostic (9.21e-2)" 3.5 8.9 4.7 5.8 4.7 9.1 5.1 4.3 6.4 5.7 5.8 6.8 12.5 4.6 12.3 7.4 9.9 7.6 4.5 4.5 4.5 28.0 8.3 5.1 6.4 4.5 4.5 4.0 7.9 14.5 14.1 4.5 4.3 6.5 7.4 8.8 6.8 4.8 3.6 4.4 9.6 4.2 4.4 3.9 6.3 48.6 4.8 9.5 12.0 3.7 6.4 5.6 4.2 4.4 38.9 25.1 17.4 25.2 13.6 11.3 9.1 21.2 22.4 27.8 21.4 11.5 26.4 29.3 19.3 19.0 15.6 29.5 16.1 24.0 30.0 25.1 17.4 17.2 21.0 24.2 8.7 58.5 21.5 7.0 12.0 29.5 18.3 10.8 16.6 31.2 24.3 24.9 27.0 29.6 27.7 35.1 24.5 33.0 26.6 29.7 19.9 34.5 34.1 13.6 22.0 20.1 23.1 25.4 25.7 14.4 30.9 31.6 9.9 29.2 35.6 26.6 37.1 6.6 16.8 35.5 27.3 65.4 38.5 0.0 1.4 0.8 2.8 2.3 3.8 6.9 4.1 3.1 1.8 6.1 4.5 3.8 0.8 2.1 6.0 5.0 4.5 1.8 4.7 4.7 4.3 6.4 4.5 4.5 4.5 4.5 4.3 4.4 4.8 4.4 2.5 6.4 13.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 8.6 6.5 0.0 0.0 8.1 5.5 0.0 23.7 2.3 0.0 37.2 16.5 0.0 15.0 3.7 3.6 0.0 0.0 0.0 10.9 12.0 3.5 0.0 3.6 3.8 7.4 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 10.3 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.5 0.0 0.0 86.1 27.7 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 6.7 2.0 9.3 0.0 0.0 CERS2 "FLJ10243, LASS2, SP260" ENSG00000143418 "Ceramide synthase 2" Q96G23 1 150960583-150975003 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 732.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027262, HPA078737" Approved Supported "Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" "Nuclear membrane, Endoplasmic reticulum" "HPA027262: AB_1852717, HPA078737: " "unprognostic (1.01e-1)" "unprognostic (2.70e-3)" "unprognostic (3.72e-2)" "unprognostic (1.29e-2)" "unprognostic (8.23e-2)" "unprognostic (2.03e-2)" "unprognostic (7.05e-2)" "unprognostic (1.60e-1)" "unprognostic (2.34e-1)" "unprognostic (4.05e-2)" "unprognostic (8.17e-3)" "unprognostic (1.11e-1)" "unprognostic (2.63e-2)" "unprognostic (1.56e-1)" "unprognostic (7.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" 95.0 307.2 126.3 53.1 171.3 80.1 100.1 170.2 165.7 96.8 141.7 81.5 94.5 79.9 89.6 46.2 94.1 97.1 71.8 125.5 144.8 261.4 732.2 135.0 56.4 201.5 168.5 104.4 129.3 159.4 84.7 113.8 192.1 83.2 88.6 38.1 61.5 82.7 37.5 46.9 102.8 99.2 158.7 65.1 128.0 49.8 157.2 67.5 161.4 57.3 69.9 91.0 70.7 223.7 154.3 175.8 138.1 277.9 395.1 237.1 100.8 153.1 217.9 278.1 189.1 188.4 248.5 137.7 244.3 242.4 174.6 165.5 195.5 160.7 247.6 194.0 157.7 193.4 107.5 219.3 277.6 216.4 218.5 214.0 197.9 254.3 315.6 341.4 174.3 189.8 210.4 281.0 363.4 255.6 134.2 135.7 200.9 499.4 299.6 160.0 95.4 208.4 311.5 127.2 121.7 185.8 169.6 278.7 183.8 172.1 335.6 296.5 145.4 196.4 93.6 180.1 267.9 189.5 229.0 841.7 222.4 91.0 200.7 212.1 80.2 136.0 76.9 43.7 93.6 34.6 70.3 78.8 69.5 31.9 60.6 60.1 86.5 63.4 32.8 70.1 86.7 88.5 126.3 171.3 170.2 165.7 125.5 144.8 201.5 168.5 192.1 158.7 157.2 223.7 46.3 67.3 67.9 8.8 23.1 24.1 38.2 37.0 18.2 7.5 52.8 27.6 2.8 120.1 23.2 53.3 4.2 77.8 40.2 60.7 13.7 104.6 7.5 24.9 39.9 47.9 24.6 24.8 5.5 92.8 42.4 44.2 16.3 29.7 36.8 33.0 38.9 200.5 55.9 3.3 5.9 29.3 30.5 45.2 35.2 7.9 56.2 54.5 37.4 5.6 39.4 26.5 26.8 7.5 51.3 103.7 32.4 40.3 29.2 52.4 98.8 81.7 21.2 9.9 39.5 37.2 33.8 13.8 6.8 13.9 15.6 54.2 34.3 39.0 29.1 34.2 CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 23.3;Cardiomyocytes: 37.1;Cytotrophoblasts: 17.7;dendritic cells: 20.2;Extravillous trophoblasts: 16.8;Hofbauer cells: 36.8;Plasma cells: 12.4;Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 132.3;WM-115: 118.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoplasm "HPA035645: AB_10600700, HPA042608: AB_2678075" "unprognostic (2.45e-1)" "unprognostic (7.16e-2)" "unprognostic (6.56e-3)" "unprognostic (1.53e-2)" "unprognostic (2.44e-1)" "unprognostic (9.29e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.29e-2)" "prognostic favorable (1.24e-5)" "unprognostic (9.12e-2)" "unprognostic (2.29e-1)" "unprognostic (2.83e-1)" "unprognostic (2.91e-1)" 38.1 26.1 12.4 16.5 16.1 27.2 17.6 18.0 15.4 33.9 14.0 20.8 18.7 20.6 15.1 24.9 22.4 23.3 20.8 14.0 15.1 27.9 31.2 24.3 20.3 14.7 17.5 23.1 16.4 26.1 8.0 22.9 16.7 24.3 19.6 18.2 14.0 19.9 28.9 18.7 21.1 18.3 14.7 25.3 23.5 28.8 15.5 21.2 49.9 28.3 22.7 23.7 16.0 17.6 44.9 22.7 21.6 19.0 132.3 36.6 29.0 24.8 30.8 18.8 24.8 34.4 25.3 21.5 52.3 26.9 25.8 26.7 33.4 34.4 28.6 27.1 15.2 18.2 24.4 18.4 33.6 18.2 20.1 27.9 23.8 22.3 24.9 30.5 22.1 28.3 33.0 32.0 25.0 23.0 21.6 13.2 27.9 10.2 16.8 18.0 28.5 20.2 30.5 54.0 16.4 16.5 31.6 21.6 31.8 45.4 21.3 30.5 30.1 12.6 15.1 22.8 20.3 29.1 41.6 24.8 21.4 30.7 118.2 9.6 19.8 16.0 8.2 22.4 7.8 9.1 8.3 7.7 14.5 9.1 7.7 7.8 29.6 7.8 25.4 8.3 13.0 9.0 12.4 16.1 18.0 15.4 14.0 15.1 14.7 17.5 16.7 14.7 15.5 17.6 23.3 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 17.7 20.2 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 16.8 10.5 0.0 0.0 0.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 27.8 3.8 0.0 0.0 0.0 CETN2 "CALT, CEN2" ENSG00000147400 "Centrin 2" P41208 X 152826994-152830757 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 243.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 639.9;Proximal tubular cells: 345.8;Respiratory ciliated cells: 1116.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001470, HPA028956" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Centriolar satellite, Cytosol" "HPA001470: , HPA028956: AB_10601798" "unprognostic (3.32e-1)" "prognostic favorable (7.54e-6)" "unprognostic (7.73e-2)" "unprognostic (2.14e-2)" "unprognostic (2.14e-1)" "unprognostic (5.73e-3)" "unprognostic (9.58e-3)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" "prognostic favorable (9.97e-4)" "unprognostic (5.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.32e-3)" "unprognostic (5.90e-2)" "unprognostic (1.25e-2)" "unprognostic (1.34e-1)" "unprognostic (2.20e-1)" 30.2 41.0 61.8 19.8 62.3 26.2 40.3 58.3 80.4 64.6 90.5 54.6 15.2 57.6 116.2 37.2 243.6 31.7 34.6 60.6 65.8 74.7 31.5 39.8 16.0 68.0 75.8 57.2 24.0 55.7 73.9 21.4 70.4 50.3 25.8 40.1 24.4 77.7 19.6 23.8 21.6 54.8 67.4 16.8 29.3 23.3 64.8 21.0 67.2 20.2 21.9 37.3 36.1 67.1 145.2 65.0 78.8 59.6 102.5 110.5 31.4 61.6 73.8 79.9 60.9 29.5 75.8 51.6 157.8 83.1 128.8 55.3 55.3 76.7 94.1 23.2 40.0 11.5 32.1 86.6 38.5 48.7 12.5 67.0 99.2 74.1 39.1 95.4 64.0 40.3 31.0 20.9 78.3 67.9 36.4 53.0 27.5 119.9 82.6 31.9 57.2 53.2 146.9 35.4 38.5 50.0 41.2 42.2 38.2 70.8 45.4 37.2 59.8 56.0 44.9 111.9 69.9 20.9 29.7 81.0 118.3 28.9 28.0 19.9 11.4 35.9 11.7 13.6 14.2 11.9 11.5 13.1 13.5 9.7 12.2 12.5 10.9 12.3 13.7 20.0 10.5 11.8 61.8 62.3 58.3 80.4 60.6 65.8 68.0 75.8 70.4 67.4 64.8 67.1 21.6 51.3 35.7 3.9 19.2 22.6 52.4 201.6 21.6 13.6 46.1 47.6 37.1 64.3 155.8 169.2 6.2 66.6 16.2 13.8 238.7 100.3 60.1 639.9 65.4 29.6 37.1 33.2 4.2 41.1 69.8 42.9 12.2 68.7 24.6 41.0 44.3 96.5 50.0 13.5 3.5 31.7 150.5 23.7 21.3 72.5 67.7 27.3 37.4 1.9 27.8 104.4 20.6 0.5 2.5 39.6 16.0 111.7 16.6 29.3 15.4 345.8 1116.5 29.4 19.7 22.7 64.2 76.5 70.4 33.7 30.5 41.5 19.7 51.8 29.2 42.4 CHCHD3 "FLJ20420, Mic19, MICOS19, MINOS3, PPP1R22" ENSG00000106554 "Coiled-coil-helix-coiled-coil-helix domain containing 3" Q9NX63 7 132784870-133082090 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 125.6;skeletal muscle: 351.7;tongue: 243.0" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 210.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042935 Enhanced Supported Mitochondria NA NA 13000 "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA042935: AB_10794538" "unprognostic (1.53e-1)" "unprognostic (2.50e-1)" "unprognostic (4.15e-2)" "unprognostic (3.00e-3)" "unprognostic (5.69e-2)" "unprognostic (4.75e-3)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.39e-2)" "unprognostic (1.28e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-3)" "unprognostic (2.04e-1)" "prognostic favorable (1.15e-4)" "unprognostic (4.98e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-1)" "unprognostic (8.03e-2)" 40.4 33.3 18.0 29.0 19.4 51.5 32.8 21.7 25.4 25.5 22.2 45.5 56.7 28.0 19.2 28.3 25.5 22.5 125.6 20.1 19.3 54.8 32.1 26.4 30.3 19.6 19.0 27.2 26.6 59.7 17.2 30.2 19.2 25.4 49.7 40.3 24.3 28.6 351.7 20.8 42.2 37.1 17.7 21.9 31.6 16.8 18.2 42.5 35.6 243.0 29.8 31.8 23.0 21.5 102.0 103.8 99.7 138.9 70.6 64.9 60.2 97.0 90.3 106.7 117.4 121.0 108.9 83.1 37.6 61.1 237.1 69.1 117.0 82.7 148.7 113.4 111.8 85.9 101.9 70.7 139.3 194.7 62.1 59.0 55.8 146.9 151.7 53.2 75.9 107.6 186.1 74.2 100.1 134.3 284.0 169.9 165.1 160.3 117.2 140.6 146.2 119.8 103.9 83.1 127.4 158.8 80.5 62.4 186.7 67.6 52.5 116.2 63.5 101.8 44.3 162.0 176.7 71.3 100.4 206.6 161.1 163.9 146.6 42.3 43.7 33.2 30.5 62.8 28.9 38.5 27.6 29.6 57.9 23.2 23.9 26.9 6.4 45.2 52.1 49.5 41.9 34.0 18.0 19.4 21.7 25.4 20.1 19.3 19.6 19.0 19.2 17.7 18.2 21.5 32.0 25.6 26.2 103.8 36.5 34.9 28.7 56.9 31.9 26.5 29.0 25.7 138.8 38.6 36.2 14.7 22.9 69.7 29.0 40.4 125.2 61.5 99.6 27.8 33.6 34.3 35.9 64.3 201.3 60.7 79.5 38.9 32.6 22.4 34.2 34.6 17.2 20.7 78.4 15.2 210.5 48.9 30.5 27.3 44.4 103.4 31.4 38.3 37.4 100.2 49.7 34.2 37.0 161.4 143.5 50.1 31.0 35.3 46.5 44.4 50.7 88.8 29.6 27.0 32.9 43.4 53.5 20.9 29.2 37.0 40.3 68.4 34.0 55.8 73.1 42.6 CHCHD6 "CHCM1, MGC13016, Mic25, MICOS25, PPP1R23" ENSG00000159685 "Coiled-coil-helix-coiled-coil-helix domain containing 6" Q9BRQ6 3 126704240-126960420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Late spermatids: 106.6;Melanocytes: 172.5;Spermatocytes: 119.7" "Cancer enriched" "Detected in all" 4 "melanoma: 34.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047673, HPA051975" Approved Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Mitochondria "HPA047673: AB_10961761, HPA051975: AB_2681679" "unprognostic (3.94e-2)" "prognostic favorable (7.46e-4)" "unprognostic (6.20e-2)" "unprognostic (1.91e-2)" "unprognostic (2.60e-1)" "unprognostic (1.16e-1)" "unprognostic (6.83e-3)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.79e-2)" "unprognostic (2.08e-1)" "prognostic favorable (6.76e-4)" "unprognostic (6.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.11e-3)" 9.4 12.8 22.2 3.8 24.7 4.2 10.8 17.7 34.3 13.1 16.4 11.6 3.9 11.5 5.0 10.9 13.7 5.0 11.9 35.0 22.7 14.4 7.4 10.7 3.9 19.0 21.6 17.7 14.8 15.6 16.5 4.1 21.0 10.5 3.0 8.3 14.1 7.8 4.7 16.3 6.2 5.4 18.4 6.9 11.7 53.0 21.4 4.9 13.0 3.2 2.9 11.1 11.5 22.1 37.1 21.1 18.4 44.7 6.4 9.8 10.5 14.1 9.5 16.0 15.5 29.3 15.8 16.3 31.8 8.5 17.5 21.3 13.9 38.3 7.9 4.5 37.7 13.5 15.8 29.0 19.0 29.2 8.5 9.9 22.9 7.8 16.3 13.1 10.6 28.4 12.2 9.4 14.2 27.7 43.2 29.1 22.3 20.9 23.7 22.8 28.0 38.9 14.3 15.8 33.6 21.0 14.5 24.3 45.4 9.0 14.2 10.8 9.7 17.9 22.2 24.5 14.6 12.0 5.9 20.4 20.1 9.6 17.0 0.0 2.4 2.1 6.8 4.1 8.8 8.4 9.9 8.4 6.8 11.6 9.4 11.2 0.0 7.7 3.7 4.8 10.0 4.6 22.2 24.7 17.7 34.3 35.0 22.7 19.0 21.6 21.0 18.4 21.4 22.1 8.9 19.2 12.5 20.5 7.1 29.6 21.7 35.5 9.6 15.4 20.0 31.5 18.5 8.6 24.0 14.7 18.8 40.8 3.4 6.4 58.7 22.7 99.0 18.6 8.8 7.3 7.7 8.2 48.1 24.2 12.1 14.8 9.7 5.8 14.0 45.6 6.8 7.2 178.2 20.2 45.1 10.8 28.5 10.1 15.6 106.6 15.8 33.0 172.5 12.2 2.7 20.2 2.1 22.6 22.0 18.9 9.0 22.2 7.1 29.6 2.6 27.9 56.1 16.1 0.0 10.9 17.9 119.7 51.4 16.0 30.1 15.5 8.2 14.1 13.3 21.1 CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA012008 Supported Enhanced Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA012008: AB_1846633" "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.71e-2)" "unprognostic (6.40e-3)" "unprognostic (8.99e-2)" "unprognostic (3.36e-3)" "prognostic unfavorable (6.03e-6)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (9.84e-2)" "unprognostic (1.66e-1)" 34.5 45.6 22.9 38.6 30.7 44.4 31.9 24.6 30.1 39.4 20.6 45.7 26.5 47.8 44.9 35.4 37.7 31.1 41.4 19.7 26.1 39.3 31.6 35.3 46.3 27.3 29.2 40.9 37.7 58.3 33.5 42.2 28.0 28.4 35.4 44.9 33.8 44.1 50.0 45.8 35.5 49.9 22.6 39.0 38.5 34.2 29.6 90.7 54.6 38.7 56.6 42.2 34.4 27.4 86.7 79.7 187.6 72.1 76.6 84.7 110.4 92.9 93.4 102.3 93.5 130.6 66.6 184.9 36.0 107.5 66.1 76.0 179.1 104.5 135.7 139.9 92.7 258.5 122.0 83.3 67.1 207.2 119.1 82.9 51.7 99.1 68.7 128.2 122.2 101.6 209.0 91.0 98.7 111.8 196.6 67.8 184.7 82.5 72.7 166.4 114.9 103.6 64.2 101.6 88.8 114.6 121.1 136.0 92.9 205.4 61.3 121.3 114.4 103.4 217.4 76.3 111.5 144.0 91.8 230.2 68.7 125.8 79.5 12.3 6.8 8.7 9.3 7.7 9.6 8.8 8.4 9.3 6.9 11.3 10.6 10.3 10.8 12.2 8.0 14.4 15.9 5.6 22.9 30.7 24.6 30.1 19.7 26.1 27.3 29.2 28.0 22.6 29.6 27.4 68.2 60.9 119.7 56.2 82.8 68.6 47.4 42.4 76.2 109.9 77.5 61.2 132.9 58.6 67.2 88.3 70.9 48.2 106.0 58.1 13.7 84.6 76.4 128.1 153.3 78.9 97.1 64.4 26.1 71.9 46.1 67.7 47.9 123.7 85.9 73.0 56.0 69.2 69.0 139.7 21.4 66.6 54.9 51.9 78.3 59.1 65.9 68.9 48.0 25.3 66.7 71.4 56.7 24.6 55.5 95.8 36.4 74.4 69.0 49.4 45.8 38.3 82.1 57.8 52.6 112.1 98.1 102.6 111.6 78.9 67.6 68.0 85.1 83.7 72.1 47.4 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHMP2B "CHMP2.5, DKFZP564O123, VPS2B" ENSG00000083937 "Charged multivesicular body protein 2B" Q9UQN3 3 87227271-87255556 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 445.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035069, HPA052754" Uncertain Approved Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA035069: AB_10602798, HPA052754: AB_2681936" "unprognostic (7.83e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-2)" "unprognostic (9.78e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (2.11e-5)" "unprognostic (5.76e-2)" "prognostic favorable (1.74e-6)" "unprognostic (6.52e-2)" "unprognostic (2.29e-1)" "unprognostic (6.41e-3)" "unprognostic (1.21e-1)" 26.0 24.2 15.7 22.8 20.2 42.7 26.3 22.3 22.2 28.9 16.2 41.6 38.5 29.5 22.5 35.2 22.6 28.8 27.0 15.1 18.2 29.6 34.5 22.9 21.9 25.1 21.0 24.9 29.2 24.3 30.4 25.0 24.1 34.9 37.5 15.3 24.9 27.7 35.3 26.4 40.8 29.6 23.7 22.1 31.1 16.1 20.3 17.2 43.1 28.0 21.6 42.3 29.7 31.2 68.4 71.6 25.4 17.4 45.0 38.4 29.7 52.8 71.2 45.1 57.1 57.0 115.0 25.3 36.7 60.1 38.6 35.0 31.6 37.6 56.0 41.7 34.7 29.5 24.6 25.4 39.2 44.9 42.5 29.3 63.2 42.9 58.3 42.6 35.8 29.6 17.3 36.7 50.2 53.2 41.1 18.3 32.4 91.1 65.5 21.4 31.0 26.1 36.0 71.3 9.7 10.8 54.2 45.6 91.4 28.8 40.6 13.7 30.6 42.9 36.5 445.0 37.7 37.7 56.3 41.6 47.6 24.8 30.9 124.7 50.7 136.7 27.3 65.2 37.3 49.6 34.6 34.8 55.1 53.4 32.0 32.4 96.8 31.4 67.8 31.3 52.4 37.8 15.7 20.2 22.3 22.2 15.1 18.2 25.1 21.0 24.1 23.7 20.3 31.2 56.2 83.3 68.7 11.4 58.7 132.0 254.5 90.0 53.5 19.9 59.8 52.1 68.8 62.9 85.0 49.7 4.2 75.4 45.7 268.7 138.9 170.6 6.8 86.7 45.2 54.4 46.7 36.2 14.1 261.2 187.0 68.9 48.4 86.9 74.1 27.1 48.5 60.8 86.9 37.0 15.1 80.3 73.2 61.9 87.6 7.5 66.2 72.6 40.9 9.4 62.0 213.9 42.2 10.6 36.0 237.4 241.3 96.3 30.0 226.0 101.7 145.8 90.5 16.3 72.3 58.5 57.5 78.7 76.7 62.8 145.6 180.9 52.9 38.1 81.3 330.3 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CISD2 "ERIS, Miner1, NAF-1, WFS2, ZCD2" ENSG00000145354 "CDGSH iron sulfur domain 2" Q8N5K1 4 102868974-102892807 "Disease related genes, Human disease related genes, Predicted membrane proteins" Autophagy "Deafness, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 256.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015914 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "HPA015914: AB_1846794" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (6.54e-3)" "unprognostic (8.02e-2)" "unprognostic (2.78e-2)" "unprognostic (3.56e-2)" "unprognostic (1.17e-3)" "unprognostic (3.48e-3)" "unprognostic (9.12e-3)" "unprognostic (2.04e-1)" "unprognostic (2.54e-1)" "unprognostic (2.86e-1)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" 11.2 19.1 2.4 5.5 2.7 6.0 9.0 3.9 3.2 9.5 4.1 11.5 1.7 9.5 5.3 12.5 8.8 4.3 10.5 2.6 3.2 17.9 46.0 10.7 5.5 2.9 2.9 8.9 20.0 5.4 12.8 3.1 3.0 9.5 3.8 6.1 12.0 1.9 7.4 9.7 10.9 3.0 2.7 14.7 11.4 6.5 3.0 4.0 13.6 1.7 3.5 9.8 10.1 4.0 16.8 5.5 5.8 7.2 14.2 15.2 3.7 12.6 4.6 5.4 8.2 6.5 27.7 12.1 10.9 12.2 12.9 8.1 28.2 10.1 24.8 10.7 4.2 10.5 3.6 6.7 10.1 18.7 16.1 5.9 15.1 23.0 17.8 5.2 9.8 6.7 22.7 21.3 14.7 4.6 16.5 5.4 11.2 5.7 4.0 6.7 5.9 22.2 13.6 5.3 13.4 7.8 7.5 12.8 12.8 6.6 8.5 4.0 4.4 15.8 17.8 21.3 7.8 16.3 23.5 24.2 11.2 5.7 12.6 4.6 2.8 5.8 2.6 2.7 2.7 2.5 2.6 2.7 2.7 2.1 1.7 2.2 2.0 4.4 3.1 3.5 3.5 2.3 2.4 2.7 3.9 3.2 2.6 3.2 2.9 2.9 3.0 2.7 3.0 4.0 24.2 25.6 26.1 10.1 65.3 85.7 45.3 131.0 60.3 33.5 61.2 51.3 27.8 58.6 70.4 77.3 20.9 74.2 52.7 52.9 72.4 101.8 12.2 39.9 41.8 35.8 43.0 256.8 17.5 77.2 131.0 39.6 39.8 48.3 57.8 24.2 26.0 159.9 110.9 30.3 22.1 94.2 146.5 93.5 128.9 6.9 23.9 66.4 69.4 12.2 78.4 36.9 45.3 17.6 25.9 74.3 88.5 33.8 194.3 63.7 82.7 203.9 63.1 33.1 32.9 22.1 41.6 41.7 36.7 56.4 90.1 56.8 54.0 33.4 68.6 53.9 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" 21.1 34.5 20.1 20.6 28.7 12.3 31.9 29.1 30.2 23.9 20.5 47.5 30.1 18.7 29.4 40.7 26.4 38.0 35.3 22.8 30.5 36.4 25.7 21.2 17.3 32.3 41.0 23.1 41.0 37.2 18.2 24.1 32.1 32.7 52.6 78.3 78.0 21.8 24.7 29.1 29.8 17.8 32.3 16.7 41.2 33.3 26.5 21.0 37.0 22.1 24.5 37.4 17.1 42.0 32.6 33.2 48.7 62.1 96.1 80.8 24.0 42.9 53.5 28.3 34.3 23.7 72.2 40.0 26.1 35.9 32.7 27.2 61.2 26.6 46.9 35.9 24.4 33.8 50.6 27.3 65.8 41.0 54.2 56.6 59.7 50.5 49.5 117.4 51.7 55.2 85.1 88.0 49.7 11.8 56.2 9.4 20.0 56.2 22.4 25.0 21.5 31.6 58.1 66.6 51.9 51.5 38.4 40.9 66.9 39.3 27.9 19.2 43.5 22.5 25.3 36.5 33.7 39.3 64.3 35.5 67.6 15.4 60.8 3.8 4.1 2.9 5.0 4.8 6.5 5.0 3.7 4.7 5.7 3.8 5.7 5.2 2.9 4.5 4.0 7.1 4.7 4.7 20.1 28.7 29.1 30.2 22.8 30.5 32.3 41.0 32.1 32.3 26.5 42.0 35.5 32.1 26.2 58.8 30.7 11.3 25.7 21.5 20.5 90.3 54.6 27.9 66.5 42.9 25.3 62.5 131.3 23.8 23.1 118.3 7.9 37.2 88.1 46.9 35.9 35.2 66.9 83.1 102.4 44.3 18.7 29.5 51.5 51.8 113.0 32.3 38.6 39.3 18.6 60.6 126.1 64.2 20.3 32.9 9.8 67.4 24.5 47.8 32.0 44.0 17.1 136.7 28.8 139.7 141.5 31.9 55.3 21.1 21.4 45.3 37.1 17.9 67.8 115.1 6.6 34.6 21.5 17.2 15.5 42.8 26.1 71.1 21.0 67.0 65.4 34.0 CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;retina: 37.9;skeletal muscle: 45.0;tongue: 34.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.0;Cone photoreceptor cells: 102.2;Excitatory neurons: 45.7;Horizontal cells: 52.2;Inhibitory neurons: 54.0;Oligodendrocytes: 76.5;Rod photoreceptor cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Cell line enhanced" "Detected in many" "GAMG: 25.3;HEL: 24.3;SCLC-21H: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" 2.6 2.7 16.2 1.5 27.4 1.8 1.1 28.8 23.1 1.3 5.2 0.9 0.8 0.6 22.6 1.7 2.9 2.1 12.3 19.6 19.7 2.8 3.2 3.0 2.8 27.1 24.1 1.6 2.2 10.8 5.3 1.1 24.5 1.5 0.7 37.9 2.2 1.0 45.0 1.0 0.7 0.7 18.5 2.6 1.5 1.8 26.8 2.6 6.5 34.2 1.8 1.2 0.7 33.3 5.9 4.6 2.7 0.0 1.5 2.5 0.1 0.2 0.0 0.0 0.0 9.1 4.6 5.0 13.0 1.5 25.3 1.4 1.4 2.9 0.2 0.1 5.7 24.3 2.2 3.5 7.3 0.0 0.1 12.9 3.4 7.0 1.5 4.7 9.4 0.0 1.5 0.1 3.3 1.1 0.0 0.2 4.0 7.1 15.3 0.0 4.5 0.0 2.1 0.8 24.1 8.7 8.6 1.1 0.0 2.7 1.7 2.7 7.4 3.1 5.8 15.3 0.6 0.5 12.1 1.8 10.5 0.0 4.5 1.6 0.3 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.4 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 16.2 27.4 28.8 23.1 19.6 19.7 27.1 24.1 24.5 18.5 26.8 33.3 1.0 9.6 3.1 11.8 4.9 0.5 0.6 2.0 0.0 85.0 1.1 0.4 31.1 8.6 2.2 7.3 102.2 0.2 0.0 0.1 0.0 2.5 0.1 2.6 1.3 3.0 15.0 9.4 45.7 3.6 0.1 4.0 1.1 3.1 1.3 0.7 13.6 5.1 3.1 52.2 54.0 0.6 4.1 4.8 2.3 0.0 0.9 3.4 0.0 15.9 1.0 15.4 0.0 24.6 76.5 4.1 0.1 3.8 0.4 0.8 0.0 2.9 5.3 42.6 0.0 8.7 6.0 0.0 0.5 0.2 0.1 0.3 0.1 2.6 0.3 1.3 CLDN8 ENSG00000156284 "Claudin 8" P56748 21 30214006-30216097 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 68.9;intestine: 50.8;kidney: 69.3;salivary gland: 40.1" "Group enriched" "Detected in some" 5 "Collecting duct cells: 224.3;Distal enterocytes: 110.2" "Cancer enhanced" "Detected in many" "prostate cancer: 31.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 18 "HaCaT: 33.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA060605 Approved NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA060605: AB_2684331" "unprognostic (3.74e-2)" "unprognostic (3.12e-2)" "unprognostic (1.33e-1)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.55e-1)" "unprognostic (1.48e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 68.9 0.0 0.0 1.7 0.0 27.2 0.0 0.1 9.3 3.9 1.1 0.0 0.0 0.0 0.0 69.3 0.0 1.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.5 0.0 7.5 50.8 0.0 40.1 13.9 0.0 8.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 0.3 0.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 10.8 2.7 0.0 0.0 29.9 11.6 0.0 0.0 10.5 224.3 0.0 0.0 0.1 110.2 11.7 0.1 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.4 0.0 0.3 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 15.9 0.6 0.4 20.3 0.0 0.0 0.0 0.3 0.0 0.0 4.6 8.4 0.0 0.4 0.0 18.0 23.1 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CLEC4E "CLECSF9, mincle" ENSG00000166523 "C-type lectin domain family 4 member E" Q9ULY5 12 8533305-8540905 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 75.7;lymphoid tissue: 52.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 31.9;Kupffer cells: 158.0;Macrophages: 115.2;monocytes: 109.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 16 "classical monocyte: 128.8;neutrophil: 448.8" "Group enriched" "Detected in many" 17 "granulocytes: 448.8;monocytes: 128.8" "Group enriched" "Detected in some" 4 "NB-4: 4.3;RPTEC TERT1: 12.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA004935 Uncertain Uncertain Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" Cytosol "HPA004935: AB_2667299" "unprognostic (3.05e-2)" "unprognostic (2.01e-2)" "unprognostic (8.91e-2)" "unprognostic (3.76e-1)" "unprognostic (1.76e-1)" "unprognostic (9.71e-3)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (1.16e-1)" "unprognostic (2.11e-2)" "unprognostic (7.65e-3)" "unprognostic (1.62e-1)" "unprognostic (1.51e-1)" "unprognostic (8.44e-2)" "unprognostic (2.29e-1)" 13.3 5.4 2.3 37.5 2.1 75.7 4.5 1.8 4.4 5.8 2.2 2.2 0.4 2.3 0.4 3.2 5.5 11.8 2.5 2.3 2.9 3.6 6.6 22.4 7.6 1.3 1.3 1.7 6.2 1.7 1.9 2.1 1.2 2.3 1.0 1.3 1.4 1.2 0.7 0.9 3.1 5.7 0.7 52.3 2.5 1.1 2.0 2.2 10.5 5.0 2.3 9.6 1.7 2.9 0.1 0.4 0.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.1 0.1 2.0 0.0 0.1 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.5 0.1 0.0 1.5 0.0 0.5 0.2 0.2 0.2 0.2 0.0 0.1 0.0 4.3 0.3 0.0 0.0 0.0 0.2 0.1 12.4 0.1 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.4 1.0 0.5 0.1 1.0 0.1 0.2 0.1 0.1 1.3 0.4 0.1 0.2 128.8 0.5 0.1 18.1 0.3 0.1 0.1 0.1 16.9 0.1 0.0 0.1 448.8 0.0 0.7 0.7 0.0 30.3 2.3 2.1 1.8 4.4 2.3 2.9 1.3 1.3 1.2 0.7 2.0 2.9 6.2 0.0 4.7 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 5.7 1.8 1.8 0.0 0.0 0.3 0.0 0.0 9.0 0.3 2.1 4.4 3.5 0.0 0.0 0.0 0.0 0.1 1.4 0.0 31.9 0.0 0.0 7.1 2.1 5.6 0.0 0.0 0.0 0.0 158.0 9.0 2.9 0.9 115.2 0.0 0.0 109.5 0.0 4.1 0.0 0.0 0.4 0.0 0.4 1.3 0.0 0.0 0.2 0.7 0.0 13.1 0.2 0.4 0.2 0.5 0.1 0.0 0.1 1.1 0.0 0.0 0.1 CLINT1 "CLINT, ENTH, EPNR, KIAA0171" ENSG00000113282 "Clathrin interactor 1" Q14677 5 157785743-157859145 "Plasma proteins, Predicted intracellular proteins, Transporters" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 749.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 749.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043280, HPA056947" Supported Supported Nucleoplasm,Vesicles NA NA 540000 "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043280: AB_10793944, HPA056947: AB_2683283" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "prognostic favorable (2.95e-4)" "unprognostic (7.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (2.53e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.56e-1)" 28.6 34.4 10.3 42.8 11.9 101.1 31.4 10.6 14.8 36.4 17.7 53.9 68.3 26.4 54.2 72.0 37.8 61.4 34.2 11.8 12.7 70.4 89.5 36.3 49.4 11.8 11.9 26.9 49.3 113.2 17.8 47.1 11.4 29.5 53.4 16.0 50.8 42.4 53.1 39.7 55.7 31.9 11.0 31.0 69.2 20.3 12.4 50.7 56.0 41.0 73.8 64.5 38.8 11.4 65.6 91.7 64.3 59.8 86.3 71.0 91.6 89.7 87.5 83.4 115.9 128.7 100.0 121.3 100.3 82.6 112.0 95.8 87.1 100.4 120.7 57.9 70.4 80.6 80.4 65.2 85.5 112.9 105.6 52.5 75.6 94.7 105.6 53.6 80.0 69.6 70.6 66.1 69.9 56.7 88.7 60.5 67.8 63.6 93.9 78.8 96.9 103.0 84.8 115.4 56.6 62.1 64.5 111.7 87.4 81.2 76.4 78.0 83.7 74.6 56.3 69.5 89.4 76.1 77.9 154.4 61.0 126.2 67.5 749.5 46.5 179.7 43.6 49.2 75.2 47.5 41.4 43.7 62.7 46.2 35.9 38.8 17.6 58.6 53.4 48.5 66.2 53.1 10.3 11.9 10.6 14.8 11.8 12.7 11.8 11.9 11.4 11.0 12.4 11.4 68.6 60.9 132.9 25.1 76.0 57.1 83.7 69.4 80.2 21.6 74.4 44.2 103.9 105.8 137.8 68.0 8.4 45.1 73.8 73.5 95.9 93.4 4.1 116.5 82.4 52.8 54.5 54.9 31.9 64.0 71.9 71.8 119.3 141.9 84.7 40.2 21.0 86.8 30.5 11.8 29.0 78.9 38.7 42.9 87.8 5.6 47.2 73.0 35.6 28.1 94.1 25.5 73.2 39.2 31.4 53.7 62.6 28.6 158.3 92.5 50.3 94.5 148.5 19.0 39.5 67.2 61.9 44.2 40.2 156.3 78.3 68.3 65.5 82.0 99.0 271.5 CLNS1A "CLCI, ICln" ENSG00000074201 "Chloride nucleotide-sensitive channel 1A" P54105 11 77514936-77637794 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017840, HPA031707, HPA031708, HPA032045" Approved Supported Nucleoplasm,Microtubules,Cytosol No No 17000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Microtubules" "CAB017840: , HPA031707: AB_2674002, HPA031708: AB_2674003, HPA032045: AB_2674123" "unprognostic (1.30e-1)" "unprognostic (3.26e-1)" "unprognostic (5.16e-2)" "unprognostic (1.30e-2)" "unprognostic (5.12e-3)" "unprognostic (5.09e-2)" "unprognostic (9.63e-2)" "unprognostic (5.56e-2)" "unprognostic (2.06e-3)" "unprognostic (5.56e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.05e-1)" "unprognostic (9.19e-2)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" 53.1 88.7 86.1 63.1 91.8 72.3 79.9 89.3 92.7 62.2 82.0 72.7 49.7 63.5 99.6 85.3 74.8 53.2 76.4 79.9 94.1 59.6 105.6 45.7 99.5 88.0 86.6 103.3 90.0 60.2 54.0 65.6 89.8 61.2 77.5 97.0 58.2 57.5 98.4 54.0 53.6 56.8 90.5 61.9 65.7 45.7 87.9 102.8 79.0 100.7 105.4 74.6 61.0 94.8 138.4 134.7 216.6 160.7 157.1 224.8 86.8 119.1 181.3 189.0 168.9 326.5 190.0 308.6 194.5 144.6 148.1 162.8 263.0 245.6 227.2 178.6 160.1 301.9 161.7 188.8 132.5 451.8 134.1 182.9 278.9 165.9 311.7 185.5 217.4 187.1 404.8 91.9 186.6 205.0 299.2 364.5 205.7 458.8 243.9 161.5 419.8 332.7 136.7 191.9 219.0 250.1 158.2 177.7 112.1 155.2 241.8 195.8 144.4 138.7 171.2 274.4 116.8 184.3 276.6 330.1 55.0 166.9 114.4 48.1 100.6 39.1 61.1 107.1 68.9 96.5 76.1 66.3 138.7 99.5 91.1 77.8 7.1 101.2 93.6 85.3 72.8 105.7 86.1 91.8 89.3 92.7 79.9 94.1 88.0 86.6 89.8 90.5 87.9 94.8 47.9 16.0 20.3 14.7 91.6 82.7 107.0 248.2 116.7 67.2 75.4 78.6 71.6 71.4 102.6 58.8 50.1 132.9 70.0 27.4 84.1 76.4 17.0 45.1 57.4 53.1 31.8 123.6 21.7 87.5 145.9 72.5 43.8 34.5 78.0 117.0 57.5 62.2 91.1 58.9 24.3 65.3 87.5 108.7 99.3 13.6 87.7 74.9 76.5 10.3 153.8 221.9 57.7 17.6 24.9 65.4 54.3 68.4 64.8 108.2 79.3 97.6 71.6 60.3 52.6 61.8 54.5 116.0 109.4 128.0 86.1 80.6 69.2 126.7 112.5 103.9 CLUAP1 "CFAP22, FAP22, FLJ13297, IFT38, KIAA0643" ENSG00000103351 "Clusterin associated protein 1" Q96AJ1 16 3500976-3539048 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 215.5;Endometrial ciliated cells: 119.2;Respiratory ciliated cells: 181.3;Rod photoreceptor cells: 116.8;Spermatocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036976, HPA044191" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Vesicles "HPA036976: AB_10602209, HPA044191: AB_2678852" "unprognostic (1.78e-1)" "unprognostic (9.28e-3)" "unprognostic (1.21e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.57e-1)" "unprognostic (3.67e-1)" "unprognostic (4.53e-2)" "unprognostic (3.63e-2)" "unprognostic (2.04e-1)" "unprognostic (8.44e-2)" "unprognostic (3.13e-1)" "unprognostic (6.94e-3)" "unprognostic (5.11e-3)" "unprognostic (8.43e-2)" "unprognostic (2.07e-1)" "unprognostic (8.94e-3)" "unprognostic (1.12e-2)" 9.7 10.7 11.1 5.9 12.6 3.9 14.7 14.2 14.5 21.1 17.8 11.0 4.2 24.2 16.0 11.1 31.8 10.6 11.4 11.2 11.6 18.6 7.7 12.1 7.4 10.4 12.7 24.6 12.2 31.4 11.7 10.6 9.1 17.0 9.8 28.9 9.1 19.9 9.9 5.6 5.4 20.2 9.8 6.6 9.0 40.0 12.0 12.4 22.0 11.6 6.0 10.8 7.8 10.4 15.7 18.3 20.8 28.9 31.4 32.0 11.0 19.9 26.7 31.4 23.7 5.1 31.3 8.2 16.5 33.7 18.8 16.8 14.7 23.6 26.2 6.6 13.1 6.9 10.3 10.5 36.7 12.5 7.2 21.1 25.4 29.1 29.4 33.1 17.2 16.4 21.7 1.0 23.6 19.3 12.0 14.0 21.5 6.6 11.1 25.9 14.3 15.7 45.7 4.9 23.2 19.8 11.6 8.8 14.3 16.0 18.7 28.8 11.5 20.8 13.8 17.1 15.0 12.8 10.9 2.2 8.0 7.3 15.3 6.2 3.6 1.2 6.2 4.2 12.1 7.3 17.8 10.8 6.8 6.1 26.9 18.4 1.3 9.0 2.4 6.6 10.3 5.8 11.1 12.6 14.2 14.5 11.2 11.6 10.4 12.7 9.1 9.8 12.0 10.4 14.5 22.4 20.5 17.0 3.5 5.6 12.3 29.1 14.8 41.0 13.4 13.8 11.7 11.5 30.6 14.7 108.4 20.7 7.5 3.3 43.0 24.3 215.5 119.2 49.7 12.4 17.5 4.6 23.6 8.0 7.7 21.9 6.6 26.4 5.1 28.1 13.6 9.2 10.4 38.7 26.3 7.9 18.3 4.9 5.7 63.4 31.4 5.0 3.6 5.6 18.1 40.7 12.3 11.1 10.3 8.6 5.3 33.1 3.5 9.4 5.3 34.6 181.3 116.8 6.6 24.7 22.7 150.0 58.4 6.4 4.1 9.3 12.1 36.7 9.0 6.5 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CMAS ENSG00000111726 "Cytidine monophosphate N-acetylneuraminic acid synthetase" Q8NFW8 12 22046218-22065674 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 532.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039905 Supported Uncertain Nucleoli,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol Nucleoli "HPA039905: AB_10795237" "unprognostic (5.54e-2)" "unprognostic (4.10e-2)" "unprognostic (4.25e-1)" "unprognostic (5.39e-3)" "unprognostic (1.94e-2)" "unprognostic (3.99e-2)" "unprognostic (2.30e-2)" "unprognostic (4.17e-3)" "unprognostic (1.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (7.19e-4)" "unprognostic (2.27e-1)" "unprognostic (1.91e-2)" "unprognostic (3.65e-1)" "unprognostic (2.03e-1)" 19.7 57.0 46.6 23.2 51.1 47.9 32.9 40.3 57.8 29.2 35.8 77.8 66.2 23.5 69.0 71.6 21.8 24.4 42.6 51.2 57.3 28.9 72.2 18.1 24.2 43.8 57.1 25.3 42.5 79.4 30.0 34.0 57.1 36.7 71.9 24.8 32.6 26.7 44.0 29.3 63.6 27.7 41.8 20.1 29.7 69.9 49.0 19.8 23.8 41.1 26.1 24.2 40.3 44.0 63.4 50.2 59.5 29.3 47.0 57.5 88.8 43.2 46.2 45.0 47.2 114.1 72.0 56.5 41.3 37.3 83.9 50.9 35.8 60.1 60.7 75.0 45.4 169.1 38.8 57.2 43.2 45.4 85.5 38.5 56.4 58.1 86.3 61.5 61.3 58.7 108.8 28.1 80.9 83.8 52.0 105.3 147.5 69.4 69.5 36.2 63.6 53.7 56.0 67.8 23.8 42.0 34.2 59.6 51.9 120.2 82.3 62.0 45.5 51.2 42.4 46.2 81.1 19.4 26.0 74.9 83.6 34.6 54.3 22.7 27.3 32.1 20.4 29.7 26.1 19.0 26.9 27.0 31.5 18.2 24.2 24.6 2.8 36.9 27.4 20.2 33.8 25.5 46.6 51.1 40.3 57.8 51.2 57.3 43.8 57.1 57.1 41.8 49.0 44.0 21.5 12.8 17.5 12.4 19.2 29.2 76.8 117.2 14.8 38.3 31.9 21.2 72.7 41.5 102.3 23.9 4.2 175.2 17.8 158.1 76.3 56.6 12.4 17.2 19.6 36.8 41.6 153.9 38.7 83.6 141.3 41.7 21.9 20.0 22.8 28.2 34.2 63.6 66.2 35.3 29.2 118.2 93.6 29.8 22.0 19.0 25.4 32.5 44.4 8.4 45.3 33.4 26.8 16.6 25.5 79.7 156.2 27.8 16.7 112.3 133.6 87.0 82.5 20.4 19.7 30.4 42.3 112.2 97.1 52.3 44.5 532.6 24.6 63.0 90.8 190.6 CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" 40.3 26.2 11.6 69.0 11.4 97.3 54.4 11.7 13.5 50.4 24.8 47.7 26.7 46.3 41.0 40.3 176.6 50.3 18.5 10.8 13.4 40.0 132.4 54.3 53.9 14.5 12.5 18.6 23.5 41.6 9.2 70.1 14.3 48.6 58.4 13.0 33.2 39.9 5.0 49.4 29.5 41.6 14.5 55.4 46.9 40.4 13.5 47.8 61.7 13.6 78.3 79.0 18.9 14.7 107.4 34.2 66.5 50.1 112.1 111.0 292.4 77.5 110.4 79.7 91.5 36.6 174.4 63.5 86.1 104.6 53.8 67.6 47.0 128.9 108.2 285.4 57.3 80.4 22.8 54.5 79.6 135.3 153.0 110.5 81.3 92.0 68.6 128.2 130.3 60.9 39.8 116.0 103.0 33.4 81.9 70.0 59.3 88.6 50.0 68.6 51.7 49.9 111.1 147.9 15.3 44.3 70.5 39.5 76.1 66.9 58.3 133.5 117.8 88.0 57.9 86.7 94.1 59.6 63.9 58.6 61.4 116.8 112.1 176.8 84.4 208.0 29.1 133.4 32.8 54.4 38.1 28.3 72.7 42.2 22.0 24.7 313.4 65.1 210.2 38.6 46.3 108.6 11.6 11.4 11.7 13.5 10.8 13.4 14.5 12.5 14.3 14.5 13.5 14.7 57.0 35.3 49.9 12.4 243.7 96.0 82.4 159.3 55.2 13.9 233.0 57.5 5.8 60.1 112.0 95.6 12.5 253.6 122.5 88.0 33.2 113.8 12.3 129.1 68.3 70.7 132.1 41.2 14.2 83.0 101.7 74.9 63.2 180.9 126.8 186.5 124.9 305.2 156.5 50.5 19.2 117.6 118.0 310.1 815.8 8.4 39.4 326.0 81.8 30.0 425.8 130.1 71.1 18.1 9.4 136.7 46.1 42.9 104.7 147.1 23.8 63.4 183.0 17.3 39.5 32.9 74.3 36.1 20.2 89.7 126.6 261.7 120.9 50.3 64.6 110.3 CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224966-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA069543: AB_2686148" "unprognostic (1.55e-1)" "unprognostic (4.49e-2)" "prognostic favorable (4.99e-4)" "unprognostic (4.61e-2)" "unprognostic (8.45e-2)" "unprognostic (3.10e-2)" "unprognostic (1.44e-3)" "unprognostic (4.54e-2)" "unprognostic (6.83e-2)" "unprognostic (4.09e-3)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (4.51e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" 31.9 32.7 21.6 39.8 25.4 51.0 42.1 35.0 30.7 28.0 20.5 43.0 38.3 39.5 45.1 43.7 36.3 35.7 38.2 24.2 26.8 50.8 48.8 33.0 52.2 19.7 23.3 42.1 36.0 62.6 26.2 43.1 20.3 32.7 43.8 78.0 38.5 29.5 78.9 27.8 38.4 36.6 21.5 39.0 32.0 52.0 24.4 80.2 60.0 72.2 64.9 45.0 20.4 24.0 77.3 93.6 138.1 103.1 57.0 59.6 95.3 97.6 82.5 110.4 97.5 110.2 60.4 106.1 103.9 85.9 177.5 60.3 147.0 122.9 160.2 44.1 71.0 139.9 68.6 119.9 73.2 95.3 82.8 57.3 99.7 94.3 100.3 102.0 133.7 138.2 119.1 114.9 112.9 60.2 234.7 88.2 152.6 144.4 72.0 126.1 102.7 79.9 95.6 167.6 173.6 115.9 68.6 60.3 114.4 112.9 72.5 79.2 90.8 82.0 116.5 92.4 110.8 59.3 208.2 189.5 76.9 88.7 82.8 138.0 93.9 109.5 80.2 116.6 95.3 133.3 109.7 95.7 113.5 135.3 136.6 110.0 84.5 106.5 105.1 101.3 134.8 130.1 21.6 25.4 35.0 30.7 24.2 26.8 19.7 23.3 20.3 21.5 24.4 24.0 46.9 32.1 40.3 15.0 100.4 90.9 65.2 82.5 100.7 114.9 77.1 64.0 58.2 61.5 48.2 62.5 93.8 88.4 74.5 31.0 97.8 79.0 86.5 50.7 37.1 56.8 94.1 60.5 39.1 72.5 115.1 45.9 40.2 53.5 44.9 72.2 69.3 67.2 69.7 25.2 32.1 69.6 81.4 73.5 58.7 33.9 40.7 59.4 26.6 28.1 83.7 68.5 76.2 23.1 34.8 79.3 58.1 40.6 84.0 93.8 52.6 113.9 56.6 219.2 78.9 51.6 56.2 95.9 100.7 90.7 86.0 85.5 77.6 55.3 70.5 84.3 CNPY2 "HP10390, TMEM4, ZSIG9" ENSG00000257727 "Canopy FGF signaling regulator 2" Q9Y2B0 12 56309842-56316119 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 475.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038465, HPA038466" Supported Supported Cytosol "Intracellular and membrane" NA NA 220000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA038465: AB_10967609, HPA038466: AB_10672646" "unprognostic (3.83e-2)" "unprognostic (5.62e-2)" "unprognostic (2.49e-1)" "unprognostic (2.46e-2)" "unprognostic (4.33e-2)" "unprognostic (2.20e-1)" "unprognostic (1.17e-3)" "unprognostic (1.46e-1)" "unprognostic (7.68e-2)" "unprognostic (2.04e-3)" "prognostic favorable (8.37e-4)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.32e-8)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (2.67e-2)" "unprognostic (5.06e-2)" 36.7 52.5 28.4 25.8 30.3 24.7 41.8 30.0 30.7 43.3 38.1 36.6 30.9 35.6 74.4 34.1 38.1 25.4 28.4 27.7 31.8 37.8 75.7 30.5 22.0 31.1 29.0 42.7 58.9 47.3 66.8 40.8 28.9 35.3 38.5 18.8 53.1 36.4 21.2 23.5 34.6 24.9 30.5 35.1 42.1 20.0 29.8 27.0 44.7 18.6 26.6 32.9 31.1 32.2 50.6 75.5 76.0 62.8 186.0 64.0 120.7 51.0 117.4 108.7 76.5 116.0 87.9 51.2 95.0 132.4 53.2 72.4 92.3 62.8 68.7 51.3 57.5 49.9 106.1 121.8 83.6 94.9 60.4 76.5 80.5 89.9 106.6 165.5 91.1 59.0 73.8 113.5 81.3 76.2 58.2 105.3 72.6 107.5 109.5 65.1 58.3 84.9 90.1 47.6 67.9 41.7 85.1 86.8 93.6 92.7 78.0 176.8 41.2 42.7 33.6 52.2 74.7 58.4 88.2 41.5 90.2 88.2 70.9 56.8 66.5 36.8 65.8 56.9 77.8 73.2 70.7 71.7 69.5 66.2 70.4 67.0 9.8 70.9 34.6 71.3 68.4 76.4 28.4 30.3 30.0 30.7 27.7 31.8 31.1 29.0 28.9 30.5 29.8 32.2 76.2 48.1 93.7 17.3 79.2 54.8 75.2 129.9 17.1 80.5 178.6 191.6 9.8 140.2 95.2 101.2 64.6 248.3 74.0 80.2 52.8 191.8 40.2 54.7 59.9 72.6 141.9 34.3 31.8 168.7 475.0 77.5 31.1 53.1 91.3 60.7 98.9 185.8 147.4 58.9 32.4 187.2 103.7 59.2 55.8 17.7 103.8 47.8 122.7 13.1 99.7 88.6 125.7 40.2 45.6 162.4 114.1 100.1 68.2 107.4 176.6 145.5 74.1 92.2 26.3 59.1 82.8 72.4 44.0 20.0 53.8 236.4 60.5 78.2 177.8 71.0 COA3 "CCDC56, COX25, HSPC009, MITRAC12" ENSG00000183978 "Cytochrome c oxidase assembly factor 3" Q9Y2R0 17 42795147-42798704 "Disease related genes, Predicted membrane proteins" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 710.2;Proximal tubular cells: 729.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031966, HPA071122" Approved Enhanced Mitochondria NA NA 13000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA031966: AB_10602115, HPA071122: " "unprognostic (1.20e-1)" "prognostic favorable (3.40e-4)" "unprognostic (5.65e-2)" "prognostic favorable (8.93e-4)" "unprognostic (7.62e-2)" "unprognostic (2.19e-1)" "unprognostic (4.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.25e-2)" "unprognostic (8.44e-3)" "unprognostic (1.52e-1)" "prognostic favorable (6.62e-4)" "unprognostic (1.64e-1)" "unprognostic (2.70e-1)" "unprognostic (3.16e-2)" "unprognostic (3.01e-2)" 64.8 73.0 122.8 30.8 122.9 15.3 63.7 128.2 160.5 71.5 125.8 110.8 106.0 55.6 172.3 128.4 73.7 42.9 102.4 125.6 124.5 223.4 158.9 45.7 41.0 124.6 125.4 55.8 172.6 106.8 59.7 38.9 127.2 84.9 89.7 34.9 66.1 66.7 119.6 58.0 81.1 41.5 125.8 50.5 128.5 25.2 125.5 42.7 57.9 94.3 49.8 60.5 78.6 125.3 66.8 219.9 99.4 54.7 89.5 75.8 61.0 51.1 77.2 119.2 107.3 87.5 81.8 3.9 141.0 62.5 112.4 63.5 77.3 124.8 111.9 65.1 202.8 44.7 96.3 280.8 63.4 61.0 52.0 77.4 92.0 112.7 64.2 61.0 96.1 31.6 72.9 55.5 106.9 108.9 20.2 132.9 45.7 135.9 78.5 79.4 145.1 113.6 122.6 90.2 73.8 61.9 52.2 54.9 91.5 85.3 170.3 78.5 59.3 129.6 67.5 55.4 69.0 65.1 76.3 36.2 97.3 60.1 89.8 206.7 209.6 141.5 136.2 208.1 143.5 218.9 140.0 138.3 178.8 187.5 128.4 126.2 22.7 187.5 177.7 120.3 191.1 245.9 122.8 122.9 128.2 160.5 125.6 124.5 124.6 125.4 127.2 125.8 125.5 125.3 55.4 28.9 68.7 7.5 44.5 36.8 52.2 192.7 50.7 36.5 99.9 110.9 263.9 173.0 113.8 266.7 20.9 153.9 30.3 233.8 710.2 136.5 13.2 203.0 70.0 65.4 79.9 54.3 8.1 239.8 177.5 72.5 103.5 154.6 35.5 77.5 69.3 390.1 121.6 45.4 9.2 205.9 195.3 75.3 33.4 18.8 55.9 54.8 88.9 6.5 86.0 94.7 63.8 6.6 11.8 134.7 201.6 45.1 73.2 79.0 221.7 729.1 145.2 37.0 39.5 46.2 88.0 48.4 52.1 242.0 55.5 102.2 43.4 97.6 258.9 67.7 COMMD1 "C2orf5, MGC27155, MURR1" ENSG00000173163 "Copper metabolism domain containing 1" Q8N668 2 61888724-62147247 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034633, HPA049223" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA034633: AB_10601800, HPA049223: AB_2680680" "unprognostic (6.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.83e-1)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.22e-2)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (4.93e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.07e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (1.27e-1)" "unprognostic (5.51e-2)" "unprognostic (2.77e-1)" 20.8 26.4 22.2 21.9 23.4 20.4 27.0 25.2 33.0 23.0 22.9 18.6 22.6 20.0 30.1 24.8 20.9 20.2 54.7 23.5 22.9 31.2 35.9 18.7 23.5 22.1 22.1 21.3 24.1 24.4 14.8 26.5 22.6 22.2 22.6 20.1 33.5 20.2 35.2 22.2 14.9 29.9 22.4 20.6 19.2 24.4 22.2 20.7 28.1 38.1 25.5 23.9 19.8 24.1 23.2 29.1 32.0 25.4 41.2 41.2 27.4 27.2 45.6 53.7 37.9 50.1 20.4 40.4 22.3 50.8 45.8 17.6 18.0 33.1 55.8 43.9 21.1 31.5 16.3 56.0 35.1 49.6 23.8 34.6 37.7 26.1 30.8 39.2 54.6 23.2 19.6 64.3 56.7 43.6 38.6 87.4 27.9 19.0 39.0 27.1 42.4 46.7 49.3 25.0 19.5 21.7 30.7 50.9 28.6 31.8 32.4 21.4 25.9 48.1 41.5 30.2 42.4 26.6 22.9 48.6 26.5 42.8 42.8 62.4 96.2 48.4 63.0 86.5 63.4 91.8 71.5 72.0 117.3 84.7 68.1 73.8 8.1 91.1 78.4 109.5 88.8 110.8 22.2 23.4 25.2 33.0 23.5 22.9 22.1 22.1 22.6 22.4 22.2 24.1 53.0 35.3 33.8 56.8 38.2 54.4 73.8 98.7 47.8 35.4 47.0 72.4 176.7 41.5 57.3 35.0 10.4 127.3 37.3 27.4 129.1 71.5 195.6 50.6 52.1 53.2 21.6 43.1 91.9 65.1 75.5 67.6 32.1 47.2 57.7 60.4 52.5 72.4 101.7 28.6 78.4 29.8 63.1 36.0 81.3 163.5 41.3 46.3 83.6 71.2 118.6 45.3 30.9 89.5 109.7 57.1 37.1 49.7 71.5 48.9 49.0 192.3 49.1 33.2 32.9 57.6 97.2 124.5 58.7 49.6 61.7 147.2 38.6 81.6 30.1 64.0 COMMD8 FLJ20502 ENSG00000169019 "COMM domain containing 8" Q9NX08 4 47450787-47463702 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035887 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA035887: AB_10600702" "unprognostic (9.04e-2)" "unprognostic (1.40e-1)" "unprognostic (8.55e-3)" "unprognostic (5.13e-2)" "unprognostic (2.51e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.07e-2)" "unprognostic (4.24e-2)" "unprognostic (3.47e-2)" "unprognostic (1.78e-1)" "unprognostic (3.78e-2)" "prognostic favorable (2.71e-5)" "unprognostic (1.06e-1)" "unprognostic (2.10e-1)" "unprognostic (7.76e-2)" "unprognostic (7.13e-2)" 13.4 15.5 9.7 20.3 9.8 21.4 13.6 10.0 14.6 11.8 13.0 17.7 18.4 10.4 22.6 24.1 11.3 13.7 27.2 9.5 12.2 45.3 12.7 13.5 30.4 9.9 10.3 10.2 10.4 26.8 13.4 19.0 10.0 10.6 18.1 13.5 8.4 10.0 8.8 17.5 19.0 15.0 10.4 18.1 14.3 24.1 10.3 21.6 21.3 12.6 25.4 16.8 11.8 10.3 32.6 17.6 15.2 7.8 31.6 44.8 21.1 47.8 31.5 30.7 41.5 29.9 37.4 51.7 39.0 45.3 69.4 17.0 49.4 39.1 55.0 30.8 22.1 29.8 17.7 23.2 43.0 73.6 36.8 38.7 51.6 29.2 32.3 28.5 39.5 33.7 22.5 20.6 75.8 18.1 44.1 59.4 10.4 21.8 22.8 21.8 34.7 11.2 88.1 26.3 29.8 15.2 19.9 16.1 39.6 26.5 29.5 48.0 32.7 43.6 41.8 39.2 57.9 21.6 27.6 42.1 47.3 95.2 32.2 114.3 58.2 68.9 44.6 80.4 48.1 48.1 40.5 44.9 74.0 43.4 37.5 43.2 29.0 57.4 89.4 34.3 51.2 71.4 9.7 9.8 10.0 14.6 9.5 12.2 9.9 10.3 10.0 10.4 10.3 10.3 31.3 22.4 16.5 3.3 41.6 22.6 11.4 60.5 21.6 18.2 12.8 16.6 46.1 18.6 32.6 29.5 4.2 86.6 39.1 20.9 107.6 42.8 68.4 43.0 21.6 26.7 21.0 14.5 5.5 46.3 116.3 28.6 16.8 19.2 33.0 11.3 22.5 12.7 90.9 6.7 7.3 19.4 42.7 54.4 42.1 18.9 54.3 50.7 12.4 4.7 82.0 37.2 72.1 2.5 5.3 25.1 23.8 40.6 22.9 8.6 28.0 231.8 57.4 23.8 19.7 16.9 29.9 141.5 59.0 37.3 30.0 105.8 53.9 36.9 28.8 10.2 COPG2 2-COP ENSG00000158623 "COPI coat complex subunit gamma 2" Q9UBF2 7 130506238-130668748 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 50.6;Oligodendrocytes: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045712 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA045712: AB_2679428" "unprognostic (9.48e-2)" "unprognostic (3.31e-2)" "unprognostic (7.98e-2)" "unprognostic (9.40e-2)" "unprognostic (3.26e-1)" "unprognostic (9.96e-2)" "unprognostic (1.74e-3)" "unprognostic (1.11e-1)" "unprognostic (6.26e-2)" "unprognostic (1.53e-1)" "unprognostic (4.41e-2)" "unprognostic (2.50e-2)" "unprognostic (6.86e-2)" "unprognostic (2.30e-1)" "unprognostic (3.23e-1)" "unprognostic (4.25e-2)" "unprognostic (2.23e-1)" 12.1 21.3 17.0 9.3 16.2 12.4 20.3 3.2 14.1 13.2 2.6 12.2 9.3 16.5 17.0 14.6 19.1 12.7 15.8 15.5 30.9 12.3 9.1 9.8 9.3 9.7 16.2 39.3 9.6 25.8 13.9 15.8 11.5 11.9 13.8 28.1 9.5 14.3 17.3 20.8 8.7 13.9 6.3 9.8 9.7 24.5 33.5 15.6 18.3 14.4 15.2 12.7 12.1 8.8 44.2 24.8 44.7 22.5 19.3 34.2 11.6 20.2 30.5 33.2 32.2 15.4 23.8 30.4 16.6 26.3 36.7 21.9 15.0 38.0 43.3 33.2 31.1 31.0 12.1 22.2 30.6 40.9 27.6 27.5 18.9 27.0 41.1 32.2 31.7 30.5 50.3 8.8 42.6 44.2 39.6 31.9 56.4 29.2 19.9 37.9 58.6 18.2 40.2 57.9 34.3 49.4 42.1 38.9 32.7 37.3 25.3 13.2 28.1 29.8 15.4 25.0 30.2 19.4 25.4 35.2 33.2 33.3 26.3 1.2 1.5 2.6 0.7 1.4 0.6 1.6 0.7 0.5 1.8 0.8 0.7 0.6 0.4 0.8 2.0 0.7 0.7 0.7 17.0 16.2 3.2 14.1 15.5 30.9 9.7 16.2 11.5 6.3 33.5 8.8 4.9 0.0 2.0 23.2 6.5 9.1 7.7 9.4 7.4 13.8 8.8 6.3 5.1 5.7 8.3 14.7 14.6 18.5 4.5 4.1 11.7 9.5 3.5 7.6 6.4 5.5 2.4 5.0 42.9 24.1 13.4 6.5 7.1 4.8 1.3 11.6 11.7 5.0 9.0 5.0 50.6 7.0 6.1 10.7 7.5 2.3 5.9 7.8 8.8 22.5 9.9 9.3 2.1 39.7 52.0 9.2 2.2 6.8 6.8 3.5 2.8 8.1 9.2 13.1 13.1 9.9 7.5 18.6 26.5 11.0 10.1 22.4 6.0 9.6 7.1 6.8 COPS4 CSN4 ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 100000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA036894: AB_10670929, HPA042828: AB_2678191" "unprognostic (1.82e-3)" "unprognostic (1.01e-2)" "prognostic favorable (4.14e-4)" "unprognostic (7.97e-3)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (1.73e-2)" "unprognostic (1.57e-1)" "unprognostic (8.96e-2)" "unprognostic (3.26e-1)" "unprognostic (3.10e-2)" "unprognostic (9.21e-2)" "prognostic favorable (5.21e-6)" "unprognostic (5.84e-2)" "unprognostic (3.07e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-1)" 25.6 38.6 28.4 22.0 30.7 41.0 32.0 26.9 33.5 31.7 26.0 27.4 23.1 30.8 28.8 30.5 26.0 22.5 59.7 30.6 35.0 38.8 29.2 22.2 29.9 28.4 29.9 31.9 24.6 43.7 39.2 30.2 32.0 30.3 25.1 45.6 23.7 30.5 104.8 26.7 22.0 33.3 28.7 22.5 22.4 45.0 30.8 36.2 38.4 84.1 32.7 31.8 23.5 28.9 51.7 30.4 64.1 59.0 56.0 71.7 34.8 67.2 85.7 74.8 66.0 43.7 51.8 86.9 57.3 140.5 41.3 37.7 80.6 68.9 101.1 55.6 56.9 50.4 43.5 42.1 46.3 86.8 135.6 54.4 47.0 55.8 47.8 56.2 101.1 53.5 65.2 48.0 91.9 43.4 105.0 63.6 35.3 81.1 40.6 74.0 48.8 48.1 59.8 47.2 67.7 39.6 45.0 69.4 43.5 43.8 52.7 46.4 66.7 52.2 55.1 39.7 48.6 49.8 32.7 96.8 50.3 55.2 52.8 91.4 37.0 55.2 43.0 50.4 53.9 39.7 47.1 49.7 45.3 38.9 44.7 48.1 8.2 54.6 59.8 29.0 47.6 52.3 28.4 30.7 26.9 33.5 30.6 35.0 28.4 29.9 32.0 28.7 30.8 28.9 25.6 12.8 20.1 21.9 34.1 42.8 42.2 94.5 23.3 38.7 20.1 23.4 81.3 20.0 51.5 20.2 31.3 82.5 36.5 14.5 90.1 42.4 130.6 24.9 27.6 31.9 31.2 26.5 34.7 33.2 62.7 39.9 15.3 21.3 34.2 38.2 20.0 22.4 49.0 26.9 32.9 22.0 67.1 29.2 29.2 38.3 30.7 27.2 33.8 18.7 37.8 62.5 37.0 28.6 32.9 28.2 22.1 42.9 28.6 20.5 22.6 75.7 37.9 44.6 32.9 34.1 42.5 121.2 50.2 29.7 35.2 95.0 32.8 53.3 26.3 34.3 COPS6 "CSN6, MOV34-34KD" ENSG00000168090 "COP9 signalosome subunit 6" Q7L5N1 7 100088969-100092187 "Enzymes, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044315 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA044315: AB_10959750" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "unprognostic (6.56e-3)" "unprognostic (1.38e-1)" "unprognostic (5.84e-2)" "unprognostic (2.09e-2)" "unprognostic (3.62e-3)" "unprognostic (2.93e-2)" "unprognostic (2.00e-1)" "unprognostic (2.45e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (6.72e-4)" "unprognostic (1.20e-1)" "unprognostic (3.58e-2)" "unprognostic (8.57e-2)" "unprognostic (8.77e-2)" 71.3 85.5 98.5 48.7 103.0 51.8 68.6 102.5 102.0 87.1 99.5 101.3 44.1 86.5 84.0 90.6 78.1 52.9 112.9 101.9 100.7 70.8 71.6 56.5 50.3 99.3 98.4 74.8 60.2 100.8 79.2 64.0 100.4 68.8 57.8 61.4 65.0 74.2 147.3 61.8 58.4 78.5 101.7 63.1 78.4 57.4 98.7 63.1 61.5 152.8 60.6 90.5 74.7 105.0 167.6 233.4 136.2 163.5 116.1 138.4 86.6 147.7 223.5 239.7 174.9 191.9 153.8 114.4 186.1 242.2 267.3 124.1 155.1 247.9 240.4 114.9 242.6 98.2 215.9 149.3 243.3 112.1 97.6 137.5 161.4 259.2 273.9 159.5 333.0 172.7 142.7 160.5 286.4 413.7 251.6 164.8 124.0 241.3 273.2 117.6 226.6 275.4 193.6 153.8 213.4 158.6 152.7 298.5 114.1 176.4 123.7 109.2 177.9 231.3 211.1 280.5 264.8 118.1 140.2 235.3 175.5 150.0 350.6 231.8 187.8 168.2 178.8 206.6 180.7 168.0 176.8 170.9 211.3 170.3 137.4 153.6 73.5 163.5 194.6 157.8 225.8 146.6 98.5 103.0 102.5 102.0 101.9 100.7 99.3 98.4 100.4 101.7 98.7 105.0 87.8 51.3 44.2 24.8 73.4 110.6 118.1 208.1 70.0 108.3 62.8 76.3 166.3 88.6 117.2 86.5 52.1 197.3 84.2 55.1 211.3 138.3 76.5 61.6 103.4 94.9 75.3 69.0 20.9 113.5 133.7 116.0 52.5 48.3 90.7 100.5 90.3 63.2 128.8 95.9 21.0 67.4 158.7 69.6 82.5 197.1 127.7 55.1 156.5 13.1 101.4 147.0 115.4 17.6 24.0 115.1 64.7 125.3 84.3 95.0 84.2 214.2 117.9 127.1 98.6 76.3 261.5 80.5 100.2 81.2 100.3 137.9 82.7 137.9 87.1 96.1 COPZ1 "CGI-120, COPZ" ENSG00000111481 "COPI coat complex subunit zeta 1" P61923 12 54301202-54351846 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 70000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic unfavorable (7.84e-4)" "unprognostic (2.79e-1)" "unprognostic (4.51e-1)" "unprognostic (7.54e-3)" "unprognostic (1.46e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (6.40e-5)" "unprognostic (1.02e-2)" "unprognostic (3.56e-2)" "unprognostic (7.44e-3)" "unprognostic (1.18e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (2.16e-1)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (3.41e-2)" 75.1 101.1 70.7 51.0 71.9 58.2 95.3 70.8 86.4 85.8 84.6 83.7 74.1 73.1 125.3 107.0 90.2 55.8 104.0 70.8 71.9 105.1 115.4 74.0 68.4 69.6 70.8 73.0 151.3 106.5 105.7 83.5 69.9 76.1 102.6 104.2 104.9 68.7 104.4 76.0 68.5 79.2 70.9 74.9 89.4 35.9 72.0 96.2 115.3 90.3 93.8 73.2 68.7 73.8 135.4 212.1 149.8 133.2 179.8 234.7 96.5 109.3 166.9 149.9 110.6 122.9 185.5 103.1 180.6 165.9 96.3 102.0 265.0 183.7 181.1 137.0 153.5 99.8 181.8 190.6 183.9 133.3 89.9 172.8 250.0 183.2 294.8 257.5 206.8 103.2 221.7 202.1 199.7 177.3 158.7 141.5 109.2 204.2 160.0 121.8 96.4 145.8 225.7 123.5 140.3 112.5 113.2 197.7 147.2 139.6 274.7 210.0 131.7 92.0 96.8 90.7 108.0 82.6 112.1 100.7 172.5 110.4 164.9 97.5 127.3 95.0 93.6 117.7 100.3 86.4 86.2 84.8 128.0 86.2 69.9 75.2 42.9 114.7 134.6 151.6 116.7 134.7 70.7 71.9 70.8 86.4 70.8 71.9 69.6 70.8 69.9 70.9 72.0 73.8 54.3 57.7 73.3 15.3 64.4 28.7 71.9 137.9 47.8 51.0 91.6 72.0 77.2 68.6 105.7 68.0 22.9 175.3 73.3 62.5 273.9 152.2 19.8 66.8 73.6 58.1 66.9 58.5 13.5 115.6 273.9 73.8 63.7 74.5 87.5 100.9 50.7 95.1 173.1 48.8 15.4 141.4 85.5 64.3 42.6 25.4 62.7 78.8 53.4 7.5 150.5 86.3 76.2 14.6 13.7 113.9 74.0 57.2 132.5 100.9 118.0 208.0 92.8 75.4 19.7 35.8 57.1 64.2 60.2 66.6 35.9 202.2 62.0 99.8 87.5 95.3 COQ5 MGC4767 ENSG00000110871 "Coenzyme Q5, methyltransferase" Q5HYK3 12 120503279-120534434 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049487 Approved Uncertain Nucleoli,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Mitochondria "HPA049487: AB_2680789" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.00e-1)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (1.60e-1)" "unprognostic (2.01e-2)" "unprognostic (6.20e-2)" "unprognostic (1.62e-1)" "unprognostic (8.37e-2)" "unprognostic (3.79e-2)" "unprognostic (2.02e-1)" "unprognostic (7.73e-2)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" 22.7 29.9 22.3 15.9 25.3 11.3 24.1 24.5 29.0 19.7 26.7 24.7 23.4 17.9 23.0 20.4 22.2 14.4 40.7 22.1 23.4 38.9 60.7 15.4 23.3 24.9 24.2 20.5 20.6 21.6 18.1 23.3 24.8 18.9 24.7 26.3 22.4 15.8 98.5 17.6 20.0 18.2 22.8 21.1 19.3 24.7 24.3 22.3 25.7 69.2 23.4 17.2 17.6 29.5 35.7 56.1 49.2 14.2 63.5 48.5 33.7 42.3 27.6 42.5 26.9 22.5 29.2 35.6 48.8 44.7 29.9 37.7 44.2 47.2 43.3 45.4 26.3 47.4 35.0 37.8 51.8 52.2 28.7 46.8 50.2 40.0 46.1 66.0 38.0 67.5 47.4 25.3 49.7 46.9 30.3 60.0 43.2 25.4 43.2 55.9 49.8 52.0 55.2 26.7 37.0 29.8 30.7 15.5 58.3 51.2 77.8 42.6 37.9 29.1 33.4 21.8 28.5 53.9 48.5 40.5 33.3 48.9 35.8 28.6 44.3 32.3 39.7 44.9 39.0 45.6 42.4 43.2 61.0 52.7 56.8 45.5 9.3 60.6 43.5 40.3 57.2 54.4 22.3 25.3 24.5 29.0 22.1 23.4 24.9 24.2 24.8 22.8 24.3 29.5 14.4 12.8 12.8 7.2 15.5 7.8 11.5 33.5 10.8 12.6 17.5 15.2 30.5 18.6 18.1 14.7 14.6 73.0 12.9 16.1 46.9 32.3 59.8 17.8 12.1 15.4 15.0 17.5 5.7 20.0 45.6 16.5 11.7 11.3 17.2 24.0 15.4 42.4 46.3 5.0 7.8 17.0 22.4 12.8 10.1 23.1 16.4 13.6 23.2 3.7 29.0 18.0 23.7 6.6 17.5 11.0 23.9 18.8 11.0 11.2 35.8 66.7 22.4 15.6 6.6 16.3 14.4 34.7 14.8 14.3 8.9 58.3 15.0 32.8 28.1 10.9 COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" 10.2 13.6 10.7 7.0 11.2 4.8 13.4 10.9 11.6 10.8 12.5 14.1 12.4 15.6 12.3 12.4 15.5 10.7 23.4 11.0 10.8 14.1 12.3 10.0 8.3 10.6 11.3 20.0 10.3 24.4 9.7 10.0 11.1 17.7 13.2 14.0 10.4 14.7 45.8 7.9 11.8 11.6 10.4 10.0 12.8 20.9 11.3 10.3 16.2 44.9 8.4 10.3 8.8 13.1 23.5 24.8 21.1 12.4 11.6 12.2 17.7 13.5 11.0 18.0 18.5 15.9 19.1 17.8 63.9 10.4 19.4 24.5 29.6 16.9 13.0 15.2 29.9 9.5 22.8 49.3 14.4 22.9 20.1 10.3 14.6 16.8 12.2 14.8 14.8 20.9 26.4 16.2 12.9 42.4 24.0 18.4 16.1 9.1 13.1 29.0 23.3 22.8 15.7 15.5 30.4 17.4 12.6 27.4 16.2 10.2 25.2 30.7 16.3 19.0 10.9 14.1 19.7 15.0 26.2 19.7 20.4 13.1 12.5 40.4 11.4 17.8 9.9 10.6 9.4 16.3 8.9 8.7 12.6 15.3 12.2 10.8 126.5 12.9 12.3 15.6 6.2 5.6 10.7 11.2 10.9 11.6 11.0 10.8 10.6 11.3 11.1 10.4 11.3 13.1 13.3 16.0 12.6 6.2 35.5 11.0 26.3 20.9 13.6 31.2 18.3 21.1 21.8 31.5 14.9 16.5 39.6 21.2 28.7 38.1 45.0 25.2 14.8 23.7 16.2 16.1 24.0 4.8 6.0 18.0 17.9 14.9 32.1 23.2 25.4 31.1 20.7 11.1 23.3 20.2 8.8 39.0 30.5 29.4 12.9 8.5 18.6 18.8 10.6 4.7 11.6 39.5 8.2 5.0 9.4 13.2 30.4 13.9 11.6 17.8 71.5 23.7 24.4 53.9 19.7 20.0 20.2 81.3 53.1 12.8 12.4 32.2 23.9 38.2 39.8 24.0 COX11 COX11P ENSG00000166260 "Cytochrome c oxidase copper chaperone COX11" Q9Y6N1 17 54951902-54968703 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044020 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA044020: AB_2678777" "unprognostic (1.42e-1)" "unprognostic (6.59e-2)" "prognostic favorable (4.30e-4)" "unprognostic (3.13e-1)" "unprognostic (5.37e-2)" "unprognostic (1.63e-2)" "unprognostic (4.69e-2)" "unprognostic (2.85e-2)" "unprognostic (4.11e-2)" "unprognostic (8.12e-3)" "unprognostic (8.18e-2)" "unprognostic (3.65e-2)" "unprognostic (2.02e-3)" "unprognostic (2.69e-2)" "unprognostic (9.25e-2)" "unprognostic (6.29e-2)" "unprognostic (7.85e-2)" 14.3 15.8 6.8 7.3 8.0 1.3 14.6 9.1 9.5 15.7 8.8 18.7 31.3 16.9 8.1 12.1 16.4 5.4 17.0 6.6 6.8 26.2 28.3 14.7 7.5 6.1 7.1 16.4 7.4 7.1 13.5 4.7 6.8 17.0 7.2 20.4 13.6 7.0 33.4 13.4 18.5 5.2 6.8 7.8 12.4 10.1 7.7 4.6 16.5 7.6 5.7 17.3 13.4 8.5 14.6 52.7 12.5 15.8 7.4 9.0 13.1 15.1 2.9 6.8 6.5 34.8 6.7 22.1 27.3 5.9 9.7 12.1 8.4 5.0 8.2 37.8 31.9 21.8 35.9 44.0 2.8 14.6 5.0 7.8 3.2 7.2 3.5 7.3 4.0 15.1 13.2 7.7 10.5 26.9 21.9 7.7 7.6 9.7 30.1 15.8 22.3 13.4 10.6 19.9 16.2 22.0 14.0 9.4 9.7 8.1 20.0 5.0 13.2 18.2 9.6 16.5 24.0 15.1 21.4 16.5 14.9 8.4 10.1 3.7 3.3 4.6 4.3 5.0 5.7 5.6 6.6 5.0 6.6 7.9 5.6 6.9 0.2 3.4 2.4 2.6 7.9 3.7 6.8 8.0 9.1 9.5 6.6 6.8 6.1 7.1 6.8 6.8 7.7 8.5 29.2 25.6 23.4 24.5 29.5 31.5 44.9 47.1 32.5 53.1 17.5 17.8 35.0 32.9 22.2 20.2 70.9 38.5 22.9 25.0 162.4 42.6 63.8 27.9 26.7 28.1 43.3 24.6 33.8 44.2 31.2 31.5 19.4 16.6 20.3 22.8 36.4 33.2 26.7 35.3 30.1 27.6 28.5 23.3 33.7 18.4 54.3 16.7 35.6 11.2 25.4 45.7 35.0 26.7 28.3 29.5 32.1 59.0 26.1 15.6 50.4 118.7 24.4 73.0 72.3 34.0 42.7 81.6 50.5 20.3 27.1 17.5 35.3 35.0 62.8 23.9 COX16 "C14orf112, HSPC203" ENSG00000133983 "Cytochrome c oxidase assembly factor COX16" Q9P0S2 14 70325081-70416984 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 302.9;Ionocytes: 187.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062659 Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA062659: AB_2684823" "unprognostic (5.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.68e-1)" "unprognostic (1.21e-2)" "unprognostic (3.63e-1)" "unprognostic (6.37e-3)" "unprognostic (1.80e-2)" "unprognostic (8.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-2)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "prognostic favorable (1.03e-12)" "unprognostic (4.08e-1)" "unprognostic (1.73e-1)" "unprognostic (3.97e-1)" "unprognostic (1.72e-1)" 19.4 27.1 20.2 18.2 19.9 22.8 27.8 20.4 29.2 16.5 22.9 26.6 30.2 12.8 27.1 17.1 17.3 19.4 24.4 20.1 20.7 29.3 40.5 16.7 21.7 21.0 20.1 17.2 43.5 26.9 12.7 14.3 20.5 20.7 22.1 24.3 21.9 13.7 84.0 17.5 26.7 10.5 20.2 18.9 33.4 17.7 20.2 20.8 23.3 44.5 19.0 19.3 12.6 22.5 100.2 31.2 65.9 56.0 26.7 36.0 48.3 55.0 37.1 38.9 34.7 19.2 93.5 26.2 36.6 33.8 33.5 41.8 27.6 35.5 48.9 18.9 27.5 36.9 31.3 22.1 16.1 35.9 48.7 36.1 25.1 24.0 23.0 41.5 34.2 69.2 20.8 54.6 39.0 49.6 85.4 43.8 68.3 83.3 44.5 57.6 53.2 37.0 46.2 49.0 57.8 46.0 46.2 102.4 53.9 42.2 87.4 69.1 42.5 50.2 111.6 55.4 40.6 57.6 38.9 48.2 75.4 19.1 61.1 48.6 33.8 8.0 24.2 38.0 29.2 45.7 34.5 29.1 36.3 39.8 32.3 34.8 2.5 45.6 38.3 55.7 43.6 44.0 20.2 19.9 20.4 29.2 20.1 20.7 21.0 20.1 20.5 20.2 20.2 22.5 22.0 51.3 53.9 0.0 45.0 84.4 9.4 302.9 70.6 8.2 29.7 18.8 7.1 32.9 162.2 23.9 2.1 14.8 22.9 23.8 52.8 47.1 2.7 43.6 21.3 28.5 31.2 46.0 0.0 64.8 20.2 36.0 99.4 62.1 33.5 7.4 31.8 57.7 18.2 1.7 0.0 35.8 187.2 34.6 89.3 4.6 18.3 40.0 96.0 0.0 26.3 25.2 25.7 0.0 0.0 59.1 27.0 15.8 99.3 11.2 42.5 48.6 137.1 10.0 6.6 13.6 27.5 15.4 21.0 125.7 100.7 10.9 39.8 7.3 39.4 14.4 CPLX2 "CPX-2, DKFZp547D155" ENSG00000145920 "Complexin 2" Q6PUV4 5 175796310-175884021 "Predicted intracellular proteins" "Differentiation, Exocytosis, Mast cell degranulation, Neurogenesis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 308.9;epididymis: 128.6;pituitary gland: 65.6" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 36.6;Excitatory neurons: 44.7;Horizontal cells: 95.9;Inhibitory neurons: 35.9;Late spermatids: 32.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "A549: 496.4;Hep G2: 323.4;SCLC-21H: 201.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA071191: , HPA074390: " "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (2.81e-1)" "unprognostic (8.98e-2)" "unprognostic (1.23e-2)" "unprognostic (5.73e-2)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (6.22e-2)" "unprognostic (1.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.90e-5)" "unprognostic (6.88e-2)" "unprognostic (2.20e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" 0.7 28.3 239.7 1.0 136.0 0.0 0.1 78.2 291.5 0.0 0.0 3.5 2.1 0.0 128.6 0.1 0.0 0.0 0.2 308.9 62.3 0.1 0.2 1.3 0.0 62.2 98.8 0.2 9.0 0.1 65.6 0.0 50.2 0.2 1.4 19.4 0.1 0.0 0.2 0.1 1.6 0.3 0.0 0.0 5.0 3.0 19.6 0.1 0.2 0.0 0.0 0.1 0.5 157.7 0.0 496.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 323.4 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.1 0.3 2.1 15.2 0.1 0.0 0.0 0.6 0.0 0.2 201.3 16.3 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.7 136.0 78.2 291.5 308.9 62.3 62.2 98.8 50.2 0.0 19.6 157.7 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 36.6 0.0 44.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 35.9 1.0 0.0 0.0 0.0 32.9 0.9 0.0 0.0 4.7 0.0 1.1 0.0 5.5 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPNE3 ENSG00000085719 "Copine 3" O75131 8 86514435-86561498 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 249.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029552 Uncertain Supported Nucleoplasm,Cytosol NA NA 71000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA029552: AB_10600703" "unprognostic (5.63e-3)" "unprognostic (1.47e-1)" "unprognostic (2.95e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (6.58e-2)" "unprognostic (8.40e-2)" "unprognostic (4.76e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-1)" "unprognostic (8.64e-3)" "unprognostic (2.77e-1)" "prognostic favorable (5.07e-4)" "unprognostic (1.15e-1)" "unprognostic (4.33e-1)" "unprognostic (1.65e-3)" "unprognostic (1.13e-2)" 35.4 29.3 14.6 22.4 17.4 76.6 42.3 23.0 15.0 40.7 24.3 35.0 32.1 33.2 21.4 73.6 32.0 30.1 52.4 15.5 19.2 51.5 46.2 33.8 39.5 15.3 17.6 39.2 29.7 52.1 11.8 25.5 17.3 41.2 34.2 18.2 37.1 29.9 17.5 36.3 30.8 31.7 16.4 28.4 30.1 8.3 16.2 38.5 60.9 26.4 46.5 34.9 25.5 21.8 135.1 46.8 30.9 40.9 116.9 92.1 24.6 63.3 93.3 51.9 58.2 30.4 44.5 36.7 40.6 77.6 31.6 101.2 68.7 67.5 92.5 39.5 52.1 6.0 27.2 34.7 41.0 2.3 1.5 63.0 71.2 57.6 76.0 83.1 64.6 17.6 33.2 68.4 65.0 51.6 65.9 1.8 10.5 110.6 64.4 30.7 28.9 174.4 67.4 92.2 66.2 51.5 55.4 249.3 39.6 35.7 95.0 10.3 69.3 44.5 44.1 61.3 49.4 47.0 63.3 9.9 66.0 12.6 42.9 28.6 32.6 54.3 33.2 38.1 26.2 26.4 27.5 23.8 63.1 26.9 23.8 26.1 46.5 27.6 52.5 62.2 20.9 32.0 14.6 17.4 23.0 15.0 15.5 19.2 15.3 17.6 17.3 16.4 16.2 21.8 84.1 137.8 103.9 23.2 52.0 81.8 110.6 111.8 96.2 16.2 80.2 73.9 120.2 75.8 89.3 69.9 14.6 73.0 85.4 49.4 99.7 77.9 1.6 66.9 73.5 66.3 50.2 28.4 37.0 83.7 55.1 92.6 48.9 83.5 8.2 44.7 66.4 103.9 50.4 45.4 39.9 55.3 81.4 71.0 93.8 4.5 85.7 64.0 53.4 13.1 75.0 75.6 36.0 58.3 24.5 59.3 51.7 87.6 49.4 112.5 53.3 126.1 78.8 17.4 59.2 102.1 77.4 3.2 8.8 183.2 91.1 78.0 55.2 71.4 75.1 91.8 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPVL ENSG00000106066 "Carboxypeptidase vitellogenic like" Q9H3G5 7 28995235-29195451 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 219.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 306.1;Kupffer cells: 290.3;Langerhans cells: 531.0;Macrophages: 266.2;monocytes: 176.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 61.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 1136.9;intermediate monocyte: 953.5;myeloid DC: 1319.5" "Group enriched" "Detected in all" 52 "dendritic cells: 1319.5;monocytes: 1136.9" "Cell line enhanced" "Detected in many" "BEWO: 190.8;RPTEC TERT1: 801.1;U-266/84: 205.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003697, HPA045715, HPA056466" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 760000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum" "CAB003697: AB_425990, HPA045715: AB_2679429, HPA056466: AB_2683140" "unprognostic (4.72e-2)" "unprognostic (7.08e-2)" "unprognostic (5.96e-2)" "prognostic unfavorable (8.56e-6)" "unprognostic (1.63e-1)" "unprognostic (2.49e-2)" "unprognostic (6.85e-3)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" "unprognostic (3.07e-1)" "unprognostic (4.25e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (2.21e-1)" "unprognostic (7.46e-3)" "prognostic unfavorable (4.99e-4)" 44.0 23.5 7.5 66.3 8.7 59.8 24.9 48.9 12.0 28.5 39.6 28.9 32.8 17.1 34.6 25.4 19.8 42.1 79.3 6.8 9.9 96.7 52.9 57.6 92.9 15.2 11.4 18.1 7.9 5.4 10.1 84.9 15.4 17.9 25.7 0.9 5.3 21.3 12.5 19.3 46.5 34.1 11.8 219.0 15.5 34.4 8.8 66.7 128.4 8.3 35.8 50.6 15.8 23.4 1.5 0.2 20.3 0.1 0.1 0.0 190.8 0.0 0.0 1.9 0.4 59.8 0.1 0.0 90.3 0.8 94.4 3.2 51.8 4.2 0.6 0.4 47.9 67.0 1.2 144.5 0.0 0.0 0.3 0.3 5.9 0.7 1.6 0.0 0.6 27.5 45.5 0.1 1.6 0.0 63.4 0.4 31.6 0.1 16.0 0.3 0.0 0.6 801.1 22.8 11.9 9.4 53.6 125.5 101.7 97.0 15.1 49.6 0.0 0.4 0.8 0.5 12.0 17.5 205.5 1.0 0.2 25.0 20.8 19.5 1136.9 5.7 2.6 953.5 3.4 1.8 1.3 1.9 1319.5 1.2 1.2 1.2 23.4 5.8 327.8 34.8 1.5 1142.7 7.5 8.7 48.9 12.0 6.8 9.9 15.2 11.4 15.4 11.8 8.8 23.4 12.3 6.4 16.0 3.3 7.2 12.5 1.3 0.7 5.7 0.0 2.6 3.4 69.1 10.0 2.5 71.7 0.0 138.0 2.1 0.2 35.2 0.5 24.7 3.7 0.3 21.1 1.8 34.1 3.7 15.6 118.3 29.4 1.1 0.6 5.1 2.3 6.8 1.1 306.1 0.0 1.7 1.2 0.0 290.3 531.0 7.6 9.3 266.2 10.6 45.9 176.8 0.2 2.1 2.0 1.3 0.8 0.4 3.0 2.9 0.5 0.4 30.6 1.5 0.4 0.0 31.0 3.0 27.1 92.8 27.2 8.8 118.5 3.3 3.6 1.2 0.9 CREB3 "Luman, LZIP, sLZIP" ENSG00000107175 "CAMP responsive element binding protein 3" O43889 9 35732598-35736999 "Predicted membrane proteins, Transcription factors" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 173.7;Late spermatids: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030978 Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA030978: AB_2673683" "unprognostic (1.73e-3)" "unprognostic (9.72e-2)" "unprognostic (9.32e-2)" "unprognostic (5.62e-3)" "unprognostic (3.61e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (4.29e-2)" "unprognostic (4.63e-2)" "prognostic favorable (5.40e-4)" "unprognostic (1.13e-1)" "unprognostic (1.65e-1)" "prognostic favorable (3.77e-5)" "unprognostic (1.48e-1)" "unprognostic (1.61e-1)" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" 26.8 45.5 41.4 16.5 42.2 7.6 26.6 38.9 47.1 29.1 37.5 38.9 14.5 34.1 37.4 16.3 28.6 20.8 27.7 39.8 43.6 29.4 26.4 24.9 14.4 43.0 43.0 26.1 32.6 29.9 38.3 20.6 43.4 37.0 23.1 23.4 31.9 38.6 24.1 18.1 22.6 35.7 41.6 20.3 36.1 44.7 42.4 16.1 26.6 20.0 19.2 32.1 21.4 40.3 39.2 35.6 36.9 30.0 77.5 48.8 22.6 64.1 111.6 69.8 73.1 45.8 19.4 10.5 28.5 108.0 87.8 15.7 25.0 52.7 53.7 37.9 14.5 8.7 44.1 24.8 97.3 16.0 19.2 42.8 45.2 72.0 73.4 66.8 42.6 19.1 11.9 24.7 81.7 22.3 22.3 8.5 19.5 30.9 39.1 18.3 15.3 15.1 69.5 25.2 15.3 21.3 22.6 23.6 17.1 34.6 39.1 7.1 46.4 52.0 27.1 35.6 44.2 12.2 13.2 15.1 55.1 7.4 55.6 24.6 33.5 11.6 26.1 32.8 31.2 28.4 26.1 29.9 37.8 20.0 20.2 18.1 12.8 28.2 29.0 31.4 27.1 28.0 41.4 42.2 38.9 47.1 39.8 43.6 43.0 43.0 43.4 41.6 42.4 40.3 24.4 28.9 17.8 3.9 27.0 35.8 55.4 62.9 20.5 29.2 35.5 27.9 13.2 30.0 43.5 16.5 12.5 49.0 29.5 50.0 33.2 89.0 173.7 26.3 19.4 33.0 26.4 3.8 4.6 70.3 54.9 34.9 25.0 25.9 32.3 20.6 25.7 23.7 35.9 5.0 5.6 67.6 32.6 16.8 59.3 413.5 30.1 22.5 49.8 1.9 42.4 50.6 38.1 3.0 5.4 72.4 42.1 42.2 53.1 65.5 71.3 62.2 56.0 18.5 32.9 22.2 47.9 73.3 32.7 11.9 22.7 61.0 24.2 22.6 29.0 46.8 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 75.0;Distal tubular cells: 19.6;Granulosa cells: 30.7;Muller glia cells: 51.7;Proximal tubular cells: 42.5;Sertoli cells: 72.3;Smooth muscle cells: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 12.4;U-2 OS: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" 6.8 143.8 29.4 1.6 21.8 0.1 3.2 64.5 32.1 69.9 4.1 16.5 0.8 83.5 1.4 3.2 24.1 2.3 288.2 30.5 35.3 40.4 2.6 11.5 0.2 44.4 41.0 133.6 51.1 0.0 20.5 0.4 36.9 26.2 0.5 5.2 1.0 10.4 2.7 2.1 3.2 10.9 26.1 1.1 4.5 31.3 44.9 0.0 2.5 2.7 0.0 27.4 29.0 22.7 0.0 0.2 1.5 0.2 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.9 0.0 0.0 0.5 4.7 0.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 12.4 1.5 3.5 0.0 0.0 1.9 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.1 1.1 0.2 0.0 0.1 0.1 1.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.1 41.8 0.3 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 29.4 21.8 64.5 32.1 30.5 35.3 44.4 41.0 36.9 26.1 44.9 22.7 0.1 0.0 0.0 4.6 0.5 0.3 0.2 0.3 0.6 9.9 0.1 0.6 75.0 0.0 0.0 7.3 2.1 0.1 0.0 0.0 19.6 0.3 1.5 0.2 6.0 0.9 0.0 0.0 6.8 10.4 0.1 5.1 0.0 0.1 0.0 30.7 0.4 0.2 0.2 6.7 11.0 0.0 0.0 0.0 0.0 5.1 5.3 0.3 1.8 0.0 0.0 51.7 0.0 1.0 0.6 2.4 0.0 2.6 0.0 0.2 0.0 42.5 0.7 3.2 72.3 0.4 19.9 2.1 0.3 0.0 0.1 0.3 0.2 0.3 0.0 0.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSF3R "CD114, GCSFR" ENSG00000119535 "Colony stimulating factor 3 receptor" Q99062 1 36466043-36483278 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 379.7;lung: 136.7;lymphoid tissue: 375.6;placenta: 105.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 230.8;Cytotrophoblasts: 423.8;Kupffer cells: 177.7;monocytes: 197.6;Syncytiotrophoblasts: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 1962.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 1962.3" "Group enriched" "Detected in some" 18 "BEWO: 70.8;NB-4: 20.3;THP-1: 50.3;U-937: 47.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017116, HPA048086" Enhanced "Intracellular and membrane" NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB017116: , HPA048086: AB_2680257" "unprognostic (5.57e-3)" "unprognostic (8.05e-2)" "unprognostic (7.23e-2)" "unprognostic (3.87e-2)" "unprognostic (2.88e-1)" "unprognostic (2.92e-2)" "unprognostic (2.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-1)" "prognostic unfavorable (5.72e-4)" "unprognostic (6.33e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (2.03e-1)" "unprognostic (2.31e-2)" 36.2 7.1 5.8 148.2 5.6 379.7 13.0 6.7 19.0 5.2 6.3 6.4 2.6 3.1 0.4 5.6 31.5 15.8 14.6 5.5 7.3 9.7 22.9 136.7 7.3 10.3 7.8 3.2 4.9 1.6 5.5 105.1 11.4 7.5 1.8 0.1 7.4 1.8 3.6 1.6 9.8 12.2 9.6 375.6 9.9 1.2 10.7 5.7 5.8 21.7 2.7 22.2 6.2 11.9 0.0 0.0 0.0 0.0 0.0 0.0 70.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 20.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 1.5 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 47.8 0.0 1.1 280.8 8.7 0.2 56.8 0.6 0.1 0.4 0.2 97.2 0.4 0.1 0.3 1962.3 3.4 24.1 3.3 0.6 158.4 5.8 5.6 6.7 19.0 5.5 7.3 10.3 7.8 11.4 9.6 10.7 11.9 0.7 25.6 230.8 0.0 3.3 1.0 0.5 0.0 0.0 0.0 5.9 4.7 1.8 0.0 10.0 0.0 0.0 423.8 2.9 0.0 0.0 0.0 0.4 0.3 6.4 4.8 0.0 4.6 0.2 0.0 47.3 8.0 1.5 0.2 18.9 1.1 3.9 1.2 64.1 0.0 0.2 0.0 0.0 177.7 39.2 0.7 0.3 111.5 0.0 77.8 197.6 0.2 6.2 0.5 0.3 0.1 0.0 0.0 0.7 0.3 0.0 0.5 6.6 0.2 0.0 0.3 1.0 0.0 0.4 0.2 0.1 1194.8 4.0 0.0 0.0 3.0 CTH ENSG00000116761 "Cystathionine gamma-lyase" P32929 1 70411218-70439851 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Calmodulin-binding, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 122.9;ovary: 34.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 38.0;Hepatocytes: 141.6" "Group enriched" "Detected in all" 5 "liver cancer: 30.0;testis cancer: 8.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 39.7;Karpas-707: 63.8;SK-MEL-30: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021591, HPA023300" Enhanced NA NA 220000 "Cluster 19: B-cells - Humoral immune response" "Cluster 62: Liver - Hemostasis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "HPA021591: AB_1847321, HPA023300: AB_1847322" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (2.76e-1)" "unprognostic (7.66e-2)" "unprognostic (2.45e-3)" "prognostic favorable (8.69e-4)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-3)" "unprognostic (5.05e-3)" "unprognostic (3.25e-2)" "unprognostic (1.03e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.26e-1)" 4.3 12.9 3.4 1.3 3.1 3.4 2.9 3.3 4.0 2.5 4.5 5.1 5.2 2.2 1.6 4.5 3.8 1.8 2.4 3.3 3.6 13.5 122.9 3.1 0.9 3.4 3.7 34.4 17.0 1.4 2.9 1.1 3.4 4.3 6.2 8.1 2.5 2.1 3.6 1.2 5.3 1.3 2.7 1.0 7.4 4.1 3.7 0.6 7.7 2.9 1.3 2.2 1.9 3.2 10.2 1.5 7.1 10.0 8.5 4.8 15.0 4.3 4.1 3.8 15.7 3.2 6.4 5.8 3.4 3.1 9.3 4.9 27.3 3.1 7.2 17.3 5.9 7.0 5.1 9.4 39.7 7.8 1.7 7.5 24.4 7.5 8.8 1.5 3.2 11.9 14.0 63.8 2.2 3.2 2.7 1.9 7.2 4.2 5.9 3.0 3.7 16.2 7.3 0.1 3.9 3.3 6.6 7.7 85.7 13.3 2.6 4.6 1.1 1.2 7.7 5.7 4.1 23.8 15.3 3.1 9.8 16.1 3.1 0.8 0.3 0.1 1.2 0.2 2.1 2.2 1.1 1.7 0.5 1.7 3.2 1.5 0.4 0.2 0.2 0.7 0.3 0.6 3.4 3.1 3.3 4.0 3.3 3.6 3.4 3.7 3.4 2.7 3.7 3.2 2.8 6.4 5.6 16.6 6.7 2.5 8.0 2.2 6.2 9.4 6.2 5.8 1.9 5.7 2.5 5.5 10.4 0.8 5.5 16.1 11.7 1.8 27.2 38.0 6.4 3.3 3.0 7.4 7.8 4.2 1.8 13.6 14.8 19.7 0.0 1.9 3.9 141.6 1.2 0.0 7.4 7.9 2.0 3.5 5.7 5.2 1.2 4.7 19.6 1.9 0.0 4.4 0.0 7.1 4.2 6.4 12.9 4.1 10.8 4.0 11.1 29.2 0.7 11.6 0.0 2.8 17.7 1.4 0.6 4.8 2.0 0.8 11.2 4.5 9.1 3.8 CTSW ENSG00000172543 "Cathepsin W" P56202 11 65879809-65883741 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.3;lymphoid tissue: 42.4" "Group enriched" "Detected in many" 9 "dendritic cells: 717.8;NK-cells: 867.2;T-cells: 352.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 8 "gdT-cell: 1376.3;MAIT T-cell: 869.4;memory CD8 T-cell: 892.8;naive CD8 T-cell: 636.3;NK-cell: 2276.1" "Group enriched" "Detected in all" 39 "NK-cells: 2276.1;T-cells: 1376.3" "Group enriched" "Detected in some" 22 "HEL: 156.7;NB-4: 363.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "CAB016345, HPA066903" Enhanced "Intracellular and membrane" NA NA 270000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB016345: AB_626813, HPA066903: " "prognostic favorable (3.06e-4)" "unprognostic (2.06e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.36e-6)" "unprognostic (1.21e-1)" "prognostic favorable (9.89e-4)" "unprognostic (5.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.25e-3)" "unprognostic (5.14e-3)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (8.84e-6)" "unprognostic (3.86e-2)" "unprognostic (3.78e-1)" "unprognostic (1.26e-1)" "unprognostic (4.01e-3)" 5.1 2.9 0.8 12.9 0.9 116.3 3.7 1.8 1.6 2.6 0.6 5.6 6.1 6.7 2.8 3.1 4.0 6.2 2.9 0.8 0.9 2.1 6.5 24.0 29.5 1.6 0.7 2.4 1.8 0.5 1.1 3.3 1.2 2.1 6.3 0.0 9.1 3.9 1.3 2.7 6.1 2.7 1.2 42.4 8.3 1.2 1.1 7.8 3.2 0.4 13.9 8.6 2.5 1.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 156.7 0.3 0.0 0.0 11.8 0.4 0.0 0.0 0.0 0.1 0.0 0.0 5.0 0.0 9.1 0.2 0.2 1.9 363.4 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 5.6 0.1 0.0 0.1 0.4 0.1 0.3 0.5 0.0 0.2 9.9 0.3 46.4 3.4 4.8 1376.3 4.0 869.4 5.1 145.3 892.8 37.6 3.7 86.0 636.3 25.7 2276.1 5.4 23.3 23.7 809.3 0.8 0.9 1.8 1.6 0.8 0.9 1.6 0.7 1.2 1.2 1.1 1.1 5.1 0.0 4.2 0.0 9.7 4.6 0.4 0.0 1.8 0.0 2.3 2.2 0.4 2.8 1.4 0.0 0.0 0.4 717.8 0.3 0.0 0.3 2.0 0.9 0.9 1.9 0.0 44.1 0.0 0.0 0.2 4.0 12.8 1.1 71.7 0.1 5.7 1.6 1.9 0.0 0.0 0.2 0.0 5.6 34.1 11.1 0.0 9.9 17.8 0.0 6.1 0.0 867.2 0.0 0.2 0.0 0.0 0.0 57.7 0.3 0.0 1.1 0.8 0.0 0.0 1.6 1.9 0.3 1.2 0.8 6.3 0.3 352.6 0.1 0.3 0.3 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.1;dendritic cells: 5.2;granulocytes: 2.5;NK-cells: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Cell line enriched" "Detected in single" 26 "HMC-1: 5.8" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 13.2 0.5 0.3 25.1 0.5 9.5 0.4 0.3 1.7 0.7 0.5 0.4 0.2 0.2 0.0 1.6 2.9 4.1 1.8 0.3 0.3 0.5 2.0 9.7 0.3 0.4 0.4 0.1 1.5 0.3 0.2 2.6 1.2 0.3 0.2 0.0 0.5 0.1 0.4 0.3 0.6 1.8 0.3 40.5 0.9 0.2 0.5 1.8 0.4 12.0 0.6 5.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 2.3 2.9 23.7 0.8 0.3 0.2 2.1 6.1 0.7 0.1 0.4 8.7 1472.7 1.5 3.2 0.9 0.3 8.3 0.3 0.5 0.3 1.7 0.3 0.3 0.4 0.4 1.2 0.3 0.5 0.3 0.0 0.0 5.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.7 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 CYB561 "CYB561A1, FRRS2" ENSG00000008283 "Cytochrome b561" P49447 17 63432304-63446354 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "pons: 124.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 432.2;SK-BR-3: 209.2;T-47d: 168.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014753 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA014753: AB_1847364" "prognostic unfavorable (8.89e-5)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "prognostic favorable (2.95e-5)" "unprognostic (1.81e-3)" "unprognostic (3.82e-1)" "unprognostic (1.37e-2)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.91e-2)" "unprognostic (8.97e-2)" "unprognostic (6.38e-2)" "unprognostic (8.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.17e-2)" "unprognostic (1.50e-2)" "unprognostic (2.89e-1)" 14.8 125.6 22.2 12.3 24.4 4.1 32.8 6.8 23.1 45.0 70.6 26.4 36.6 12.3 57.2 51.9 55.8 17.3 16.2 20.4 33.2 24.5 21.0 30.9 8.3 17.2 23.2 9.4 118.0 76.1 74.1 16.2 124.7 63.3 21.1 9.8 85.0 37.8 6.0 37.3 31.9 9.2 9.8 8.7 48.1 6.0 28.0 3.5 40.8 4.6 12.8 16.4 27.4 17.9 99.3 31.9 2.6 20.5 11.5 52.7 43.3 10.3 12.0 12.3 4.9 29.2 96.9 0.2 23.0 75.5 3.3 83.1 20.3 8.0 4.8 26.1 8.7 12.7 20.4 2.0 21.7 1.3 4.3 8.6 84.1 11.2 1.5 17.9 23.9 0.1 41.2 17.7 4.0 140.3 0.5 4.9 20.9 80.5 49.9 0.3 0.2 31.0 40.0 49.8 73.7 432.2 26.0 209.2 10.4 7.3 168.6 6.2 3.6 25.9 29.4 60.6 3.1 0.4 0.4 0.1 22.6 5.1 14.0 0.3 2.0 0.2 19.2 5.7 24.6 0.6 14.4 13.2 2.1 0.6 1.3 4.2 5.2 20.3 7.7 0.1 0.0 5.8 22.2 24.4 6.8 23.1 20.4 33.2 17.2 23.2 124.7 9.8 28.0 17.9 14.6 28.9 37.8 3.6 3.5 16.4 23.7 16.0 26.2 6.1 37.4 24.6 12.8 20.0 36.7 23.9 0.0 25.1 7.0 22.2 3.9 41.1 6.9 74.5 12.5 18.3 21.6 3.4 14.1 50.5 29.2 15.0 30.1 53.9 15.9 7.3 11.4 11.1 4.7 0.0 10.7 31.7 18.3 7.0 9.8 6.2 3.7 4.1 3.6 9.4 6.0 5.2 2.1 0.5 0.6 30.8 11.4 3.4 15.3 41.6 32.1 11.9 68.5 26.8 6.6 5.1 7.6 6.9 7.2 34.2 27.8 24.8 11.4 0.4 26.2 22.6 CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 605.2" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 187.2;Extravillous trophoblasts: 196.5;Syncytiotrophoblasts: 293.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 187.3;hTCEpi: 188.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" Mitochondria Cytosol "HPA010641: AB_1078600, HPA014147: AB_1847370" "unprognostic (6.36e-2)" "unprognostic (8.51e-2)" "unprognostic (1.16e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.86e-2)" "unprognostic (4.34e-2)" "unprognostic (8.46e-2)" "unprognostic (1.28e-1)" "unprognostic (4.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.73e-2)" "unprognostic (2.33e-1)" "unprognostic (6.14e-2)" "unprognostic (2.37e-3)" "unprognostic (1.69e-1)" 38.6 57.3 37.4 23.0 38.8 19.7 43.7 41.1 40.5 49.7 57.3 35.7 19.3 41.2 131.4 61.6 68.2 27.2 154.8 38.3 48.0 64.5 50.2 44.0 25.2 45.4 49.4 41.7 45.1 82.9 46.1 66.6 55.7 41.1 21.2 34.3 56.9 40.0 605.2 123.8 25.7 37.5 39.9 39.1 92.8 50.7 41.4 40.1 40.5 308.0 38.8 52.7 45.8 43.6 34.8 21.3 18.3 37.7 166.0 37.9 178.5 68.3 63.4 43.2 38.4 17.5 39.9 21.5 56.5 68.1 24.0 187.3 14.9 58.0 28.2 31.2 37.8 12.4 24.0 20.4 59.7 10.5 29.6 61.2 188.3 47.5 25.8 36.4 28.9 25.8 37.0 37.6 157.8 40.4 13.6 9.5 12.1 31.0 40.1 21.9 87.6 45.7 41.1 40.8 15.7 19.1 38.0 124.0 57.4 39.4 57.7 23.4 28.5 49.0 20.8 18.7 38.3 34.9 44.5 10.0 53.6 16.2 37.1 24.4 56.7 46.6 27.4 42.6 36.3 23.4 30.9 28.9 37.6 35.0 41.9 29.6 46.0 32.2 29.4 25.9 34.2 52.6 37.4 38.8 41.1 40.5 38.3 48.0 45.4 49.4 55.7 39.9 41.4 43.6 33.0 22.4 29.8 10.1 15.5 187.2 38.5 89.5 42.1 21.0 46.1 41.9 119.3 37.1 60.5 29.5 29.2 171.1 15.8 10.6 7.9 38.3 5.0 58.7 17.3 30.0 19.2 30.7 8.9 48.3 196.5 28.9 31.6 34.9 28.5 13.6 32.9 44.6 63.5 10.1 11.3 10.8 105.8 45.4 29.7 8.6 29.8 39.5 64.0 8.4 20.9 65.9 11.3 11.6 8.1 72.8 11.3 31.2 12.5 25.8 16.0 38.9 75.9 35.0 13.1 49.1 30.0 23.0 4.3 40.6 157.4 293.5 19.5 27.9 14.7 48.2 CYP39A1 ENSG00000146233 "Cytochrome P450 family 39 subfamily A member 1" Q9NYL5 6 46549580-46652830 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 99.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 62.9;Late spermatids: 20.1" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 6.5;hTCEpi: 13.6;OE19: 6.1;SiHa: 8.4;U-698: 10.4" "Region enhanced" "Detected in all" "olfactory bulb: 22.9" "Low region specificity" "Detected in all" NA NA "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.33e-1)" "unprognostic (1.62e-2)" "unprognostic (8.46e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (1.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (7.33e-2)" "unprognostic (6.11e-2)" "prognostic favorable (1.86e-4)" "unprognostic (1.54e-1)" "unprognostic (5.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" 3.0 2.5 2.1 1.0 2.7 0.0 5.4 3.5 2.9 3.7 5.3 2.7 0.8 3.6 21.0 3.3 4.1 6.3 3.9 2.0 2.1 5.7 99.2 3.3 0.5 2.3 2.3 11.5 5.7 15.3 2.9 0.4 2.1 14.8 3.6 4.1 23.5 2.6 0.6 15.9 1.6 2.4 2.4 0.7 2.8 4.2 2.4 0.4 6.1 1.2 1.4 2.7 3.0 2.9 0.2 0.4 0.3 1.8 0.3 0.0 0.0 0.0 1.1 0.3 0.1 0.0 0.5 6.5 4.4 0.0 0.9 1.7 0.8 1.4 0.0 0.0 2.8 0.0 1.7 1.8 4.0 0.0 0.0 0.5 13.6 0.0 1.6 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 1.5 0.5 1.1 0.1 2.9 4.0 0.7 0.0 8.4 0.0 0.2 0.4 1.5 0.0 0.0 0.2 0.9 0.0 0.1 0.0 0.0 10.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.5 2.9 2.0 2.1 2.3 2.3 2.1 2.4 2.4 2.9 3.3 16.0 1.5 3.9 0.2 4.0 8.8 2.7 2.8 1.4 4.6 6.5 5.8 10.0 4.3 3.7 2.1 0.0 0.0 1.1 5.9 2.9 12.7 4.4 1.0 3.5 0.0 5.3 3.2 0.4 0.9 4.5 1.5 3.1 0.0 2.7 1.1 62.9 0.2 0.0 2.0 4.0 10.2 2.5 0.9 20.1 6.2 0.3 3.6 8.4 0.0 8.6 0.0 1.0 7.2 0.5 2.7 9.4 0.0 7.9 0.3 5.3 7.2 1.5 0.0 1.9 2.3 0.7 0.8 2.6 15.3 0.0 0.2 6.3 2.5 8.1 DAD1 OST2 ENSG00000129562 "Defender against cell death 1" P61803 14 22564907-22589224 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028882 Uncertain Uncertain "Endoplasmic reticulum,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Endoplasmic reticulum" "HPA028882: AB_10602214" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (2.02e-1)" "unprognostic (1.18e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (9.43e-3)" "unprognostic (3.06e-2)" "unprognostic (6.09e-2)" "unprognostic (1.99e-2)" "unprognostic (9.64e-2)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.37e-3)" 204.0 229.3 209.2 159.1 224.4 129.0 224.0 236.2 259.4 229.6 252.2 197.7 165.8 184.3 473.8 187.0 230.5 190.8 202.6 211.4 238.0 296.8 275.7 183.4 169.6 240.2 218.7 174.5 200.2 254.1 201.6 141.8 238.7 145.5 209.9 86.2 286.3 205.5 156.6 137.2 173.8 206.6 237.2 165.3 197.0 150.7 219.2 211.6 272.8 197.5 191.0 200.0 163.4 252.0 373.3 344.7 274.6 375.8 740.2 529.9 238.3 387.0 473.0 340.5 478.1 219.6 520.1 233.7 242.1 453.1 381.4 330.0 291.1 375.7 543.3 319.8 265.1 228.5 180.9 886.0 514.5 321.2 315.8 395.8 498.7 356.0 454.4 383.1 506.2 220.9 176.4 532.1 509.9 459.3 153.6 391.4 169.7 816.1 557.8 211.7 232.4 306.7 503.2 306.1 211.5 263.4 294.9 416.1 445.9 328.7 251.4 323.1 381.1 291.8 232.2 358.2 248.3 391.2 502.6 308.5 263.8 225.5 431.0 532.4 421.9 460.9 528.4 371.9 518.9 527.2 543.8 501.4 401.0 477.1 564.8 497.6 481.5 437.2 332.3 783.9 560.3 941.8 209.2 224.4 236.2 259.4 211.4 238.0 240.2 218.7 238.7 237.2 219.2 252.0 357.9 160.3 161.7 15.0 183.9 198.3 188.3 581.8 149.7 25.1 201.0 274.6 173.8 187.3 315.2 255.6 27.1 260.9 204.6 174.8 215.2 525.4 196.8 270.3 242.9 267.8 135.7 130.2 10.6 415.2 383.1 276.5 145.2 255.6 302.6 150.8 187.7 231.9 350.3 21.9 11.0 242.3 360.1 146.2 224.8 101.5 214.3 166.8 330.8 8.4 217.3 216.8 198.8 18.1 42.5 396.8 160.7 199.0 408.6 172.5 244.8 420.8 393.7 42.6 151.2 141.5 291.0 300.3 128.1 179.6 215.8 289.0 211.7 266.6 183.8 174.4 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DARS1 DARS ENSG00000115866 "Aspartyl-tRNA synthetase 1" P14868 2 135905881-135986100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 85.1;Cytotrophoblasts: 115.4;Extravillous trophoblasts: 157.9;Hofbauer cells: 94.2;Syncytiotrophoblasts: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 37.5 42.1 30.1 41.2 31.2 34.0 48.7 33.3 52.1 34.7 28.0 38.5 23.5 38.4 22.8 46.0 37.8 25.8 42.3 29.5 35.2 47.3 44.2 27.8 48.3 32.6 31.2 47.2 36.1 38.4 24.6 44.4 35.6 33.6 26.6 87.1 32.5 36.5 82.8 40.2 28.0 39.3 34.0 32.3 33.3 17.8 30.7 63.1 43.4 60.1 55.4 40.0 36.4 35.3 201.6 77.0 73.4 66.3 61.0 78.1 141.6 99.8 92.6 92.2 91.1 163.0 84.0 210.0 159.8 78.4 86.6 111.7 94.9 114.9 170.3 95.6 86.0 134.0 76.8 185.6 83.9 188.3 90.8 84.5 75.6 109.1 99.8 122.9 46.8 106.3 131.6 66.0 66.6 87.3 139.2 117.4 77.8 85.3 66.9 179.3 157.9 139.0 91.8 76.9 40.3 89.6 75.0 63.5 74.8 72.2 66.8 118.2 38.2 86.0 87.4 64.5 92.8 194.9 123.3 250.2 144.1 132.3 51.0 33.7 85.4 51.2 115.2 82.6 174.7 219.9 172.6 151.4 133.7 198.8 175.2 154.2 31.7 171.9 67.4 130.4 168.9 153.3 30.1 31.2 33.3 52.1 29.5 35.2 32.6 31.2 35.6 34.0 30.7 35.3 29.4 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 115.4 20.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 157.9 18.2 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 136.4 4.4 0.0 0.0 0.0 DCAF11 "GL014, PRO2389, WDR23" ENSG00000100897 "DDB1 and CUL4 associated factor 11" Q8TEB1 14 24114195-24125242 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 201.2;Hepatocytes: 156.0;Proximal enterocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003583, HPA031157" Approved Enhanced Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA003583: AB_2667001, HPA031157: AB_10603002" "unprognostic (1.50e-1)" "unprognostic (4.72e-2)" "unprognostic (3.22e-1)" "unprognostic (8.45e-2)" "unprognostic (1.01e-1)" "unprognostic (9.58e-2)" "unprognostic (1.91e-3)" "unprognostic (1.48e-3)" "unprognostic (3.23e-2)" "unprognostic (4.08e-1)" "unprognostic (1.19e-1)" "unprognostic (2.01e-1)" "prognostic favorable (3.50e-13)" "unprognostic (2.58e-1)" "unprognostic (3.48e-1)" "unprognostic (6.80e-2)" "unprognostic (1.68e-1)" 15.4 41.6 21.5 13.4 21.7 39.5 17.1 19.7 23.0 15.4 19.9 24.5 29.3 17.1 23.2 29.8 15.6 13.6 38.1 22.3 19.9 35.8 107.2 17.5 15.6 21.0 20.3 23.1 59.7 28.2 25.6 9.2 19.8 23.6 16.6 17.6 25.9 17.5 62.3 20.1 37.5 11.7 19.2 28.9 34.3 16.5 22.0 19.0 26.4 50.0 16.1 20.3 16.2 21.1 12.5 18.3 12.3 10.9 10.7 8.8 16.6 9.1 10.7 16.0 19.5 12.0 21.3 19.4 10.3 12.2 13.3 16.1 15.8 9.6 7.4 23.1 9.5 15.6 19.7 67.3 14.3 27.7 31.0 5.3 23.1 6.7 16.7 13.1 12.3 31.6 15.0 23.0 9.7 39.2 23.7 28.5 7.2 35.0 17.0 25.1 16.0 28.2 12.2 28.1 22.1 17.0 5.3 29.9 13.4 12.7 15.4 19.6 5.1 12.5 10.0 13.6 13.2 38.6 36.2 25.3 6.0 17.7 10.9 14.0 13.8 20.5 13.8 15.8 11.7 12.1 12.5 13.5 17.1 11.5 12.2 11.4 11.7 23.0 13.9 8.6 16.7 15.2 21.5 21.7 19.7 23.0 22.3 19.9 21.0 20.3 19.8 19.2 22.0 21.1 18.2 28.9 45.4 10.4 30.5 8.8 22.2 18.7 31.3 34.1 34.8 20.7 41.2 44.3 23.9 38.6 47.9 34.6 34.2 76.1 46.9 41.6 19.3 22.0 10.8 15.2 28.9 201.2 9.2 46.2 31.5 14.1 29.0 22.5 12.6 26.5 22.1 156.0 37.4 16.8 6.9 40.7 20.3 27.0 12.8 26.6 9.0 24.1 17.8 9.4 39.2 38.8 55.6 7.1 9.7 31.9 34.6 14.7 26.6 25.0 147.9 56.0 22.3 29.4 26.3 15.9 14.5 23.7 12.4 32.6 11.4 50.5 31.2 60.7 49.0 22.7 DCLRE1A "hSNM1, KIAA0086, PSO2, SNM1" ENSG00000198924 "DNA cross-link repair 1A" Q6PJP8 10 113834725-113854383 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036907 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nucleoli fibrillar center" "HPA036907: AB_10673626" "unprognostic (1.22e-1)" "unprognostic (7.55e-2)" "unprognostic (4.84e-2)" "unprognostic (3.82e-2)" "unprognostic (1.09e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.74e-5)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-2)" "unprognostic (2.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.40e-2)" "unprognostic (4.05e-2)" "unprognostic (2.85e-1)" "unprognostic (3.07e-1)" "unprognostic (6.34e-2)" 2.1 3.8 3.9 3.9 4.2 4.6 5.2 4.2 5.5 4.0 4.1 4.3 4.1 2.9 5.5 3.3 4.1 2.8 4.4 4.2 4.3 6.0 9.8 3.6 5.3 3.8 3.9 5.3 7.4 8.4 2.9 4.2 4.0 5.9 5.2 8.0 5.0 4.0 3.6 3.7 4.0 3.2 3.8 4.0 5.2 4.7 4.1 5.0 5.1 3.3 5.3 3.2 1.9 4.1 15.8 13.0 19.3 19.7 2.5 4.2 11.0 9.4 9.5 12.5 14.3 10.2 21.1 12.2 10.4 4.8 9.7 12.9 18.6 8.2 16.1 24.2 16.0 20.7 8.0 13.1 8.2 21.9 18.8 2.8 9.8 10.5 18.5 8.3 7.7 16.3 24.1 12.9 7.1 9.4 10.6 8.8 9.4 12.5 6.9 6.1 23.0 8.0 8.3 7.3 8.4 13.9 5.4 9.2 13.8 13.2 11.0 10.5 6.8 7.2 14.1 9.8 15.6 14.9 18.2 18.6 10.7 31.5 10.5 1.3 0.3 0.7 2.8 0.2 1.8 0.6 1.2 1.9 1.1 0.3 0.8 1.4 0.1 1.0 0.5 0.4 3.2 1.2 3.9 4.2 4.2 5.5 4.2 4.3 3.8 3.9 4.0 3.8 4.1 4.1 0.9 6.4 4.1 4.9 1.3 0.6 0.6 2.8 0.6 4.2 2.9 1.9 9.6 5.7 3.6 1.8 0.0 3.0 2.0 2.2 7.9 1.9 0.7 2.9 1.8 1.6 3.5 6.5 4.9 1.1 1.8 2.5 1.5 2.0 1.3 3.6 1.8 7.7 3.2 6.7 4.7 2.5 4.1 3.8 0.6 0.5 1.5 10.3 0.0 2.8 3.6 3.9 2.1 8.0 4.1 1.6 2.3 1.5 3.0 1.3 1.6 3.7 5.1 3.9 0.0 1.7 1.2 6.0 5.4 2.5 0.6 0.7 3.1 2.4 3.4 0.7 DDOST "GATD6, KIAA0115, OST, OST48, WBP1" ENSG00000244038 "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit" P39656 1 20651767-20661544 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 350.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009746, HPA046841, HPA052867" Supported Supported "Endoplasmic reticulum" NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB009746: AB_2092075, HPA046841: AB_2679834, HPA052867: AB_2681977" "unprognostic (8.57e-3)" "unprognostic (1.35e-2)" "unprognostic (1.57e-2)" "prognostic favorable (5.99e-4)" "unprognostic (1.62e-1)" "prognostic unfavorable (4.88e-4)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (2.70e-2)" "unprognostic (3.59e-2)" "unprognostic (3.72e-1)" "prognostic unfavorable (9.05e-7)" "unprognostic (1.07e-1)" "unprognostic (2.98e-1)" "unprognostic (1.69e-2)" "unprognostic (1.07e-1)" 98.1 132.7 44.6 108.5 46.4 191.4 111.9 44.9 46.3 130.7 64.1 161.4 119.4 115.8 224.5 113.2 137.4 98.2 123.4 47.2 53.7 100.6 137.2 104.4 104.6 48.1 45.3 139.5 259.8 112.7 119.1 183.3 46.9 99.8 165.7 42.1 151.7 130.4 80.0 87.3 108.4 122.8 46.1 113.1 139.0 83.4 52.4 84.0 185.6 66.4 121.6 119.3 92.8 51.4 366.0 206.7 178.8 533.9 347.4 359.8 376.6 286.1 545.9 435.5 445.3 278.9 678.8 275.8 501.8 447.0 238.7 292.7 250.4 334.3 321.3 257.0 256.3 235.7 138.5 375.0 513.2 377.5 618.8 371.6 370.2 365.2 439.5 522.8 504.1 180.5 116.3 445.0 266.5 251.1 179.6 308.2 196.5 529.8 214.2 164.5 238.6 492.2 358.7 150.4 133.0 238.3 294.0 299.1 413.5 257.1 237.8 566.8 260.2 249.7 279.6 435.1 274.6 586.1 677.5 195.6 409.4 489.4 342.0 272.0 268.3 257.3 255.6 284.2 270.3 230.4 218.1 239.9 389.7 207.8 203.1 209.6 63.8 266.1 251.4 320.1 256.0 490.6 44.6 46.4 44.9 46.3 47.2 53.7 48.1 45.3 46.9 46.1 52.4 51.4 62.0 35.3 72.3 7.5 93.6 50.2 95.8 200.6 47.3 18.3 70.0 62.5 22.1 77.2 120.0 35.0 29.2 350.7 92.9 52.5 39.2 162.5 29.9 44.7 71.9 65.2 71.8 49.6 10.9 148.3 270.0 102.8 74.5 71.6 79.1 113.2 55.3 74.4 140.8 16.8 9.4 152.6 79.3 66.8 78.8 13.9 74.6 74.5 85.4 6.5 96.4 54.1 87.6 15.6 10.7 93.5 89.7 60.9 320.5 68.9 69.1 54.3 78.9 24.6 46.0 42.5 103.3 136.0 171.3 55.1 53.6 349.7 78.5 122.9 133.7 84.3 DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2;lymphoid tissue: 62.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.0;Late spermatids: 151.4;NK-cells: 88.6;T-cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 83.3;MOLT-4: 75.5;NB-4: 99.3;REH: 68.8;THP-1: 78.9;U-937: 117.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA038975: AB_10697544, HPA038976: AB_10673409" "prognostic favorable (3.02e-6)" "prognostic favorable (1.08e-4)" "prognostic unfavorable (1.71e-4)" "prognostic favorable (2.37e-4)" "unprognostic (1.93e-1)" "unprognostic (3.63e-3)" "unprognostic (2.24e-1)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (6.21e-3)" "prognostic unfavorable (1.02e-8)" "unprognostic (1.78e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-3)" 5.8 3.6 5.9 33.5 5.9 63.2 6.0 6.3 7.2 8.0 7.3 9.8 10.2 2.8 8.5 28.2 4.4 7.2 2.6 5.9 6.6 4.7 5.2 14.7 48.6 8.7 7.0 3.1 21.6 1.3 8.3 7.7 8.0 21.0 7.4 2.2 15.8 4.8 1.7 28.5 30.7 3.5 7.7 62.9 16.3 26.7 8.1 50.2 8.3 1.1 38.1 10.2 16.5 8.8 24.0 0.0 0.8 0.6 0.1 0.3 29.0 2.6 3.6 0.6 0.7 1.5 10.0 28.1 8.3 1.3 0.1 15.5 0.0 19.6 0.4 1.0 1.1 31.7 0.4 12.6 0.7 57.5 40.0 4.5 24.6 0.3 22.0 0.1 0.0 83.3 14.3 65.7 0.1 12.3 75.5 99.3 1.3 3.0 2.8 68.8 0.6 38.4 2.5 17.8 0.4 0.2 2.1 5.8 5.5 1.1 15.9 78.9 3.8 0.3 0.6 0.1 0.3 37.2 37.1 23.3 0.0 117.7 0.2 49.2 39.5 119.7 78.6 29.7 62.4 34.2 63.3 76.8 55.2 31.3 65.1 65.2 69.3 72.9 27.8 36.6 73.1 64.3 5.9 5.9 6.3 7.2 5.9 6.6 8.7 7.0 8.0 7.7 8.1 8.8 1.7 6.4 8.0 1.3 49.2 11.9 16.9 15.0 20.5 2.5 5.4 7.2 0.8 2.8 8.2 5.5 0.0 25.0 52.3 4.2 0.0 0.9 56.3 2.2 0.8 3.1 4.2 6.7 2.0 10.0 17.2 2.2 26.0 3.0 17.7 1.5 2.9 0.9 94.0 3.3 1.0 9.9 2.0 28.0 26.4 151.4 2.8 31.7 7.2 17.8 30.0 0.8 88.6 0.5 0.5 8.0 8.9 1.9 57.9 6.0 3.1 0.3 5.8 1.7 0.0 0.6 1.2 40.0 0.9 20.0 11.8 12.6 78.3 1.0 9.1 13.0 DEPDC1 "DEP.8, DEPDC1A, FLJ20354, SDP35" ENSG00000024526 "DEP domain containing 1" Q5TB30 1 68474152-68497221 "Predicted intracellular proteins" "Transcription, Transcription regulation" "GTPase activation, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.0;lymphoid tissue: 8.1;testis: 8.1" "Cell type enhanced" "Detected in many" "Early spermatids: 44.9;Erythroid cells: 31.8;Extravillous trophoblasts: 35.2;Late spermatids: 73.0;Spermatocytes: 86.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017845 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nucleoli fibrillar center" "CAB017845: " "unprognostic (2.73e-1)" "unprognostic (7.40e-2)" "prognostic favorable (8.70e-5)" "unprognostic (1.23e-3)" "unprognostic (3.06e-1)" "unprognostic (7.73e-3)" "unprognostic (4.37e-6)" "unprognostic (3.39e-3)" "unprognostic (1.57e-3)" "unprognostic (8.59e-2)" "unprognostic (9.04e-6)" "unprognostic (2.18e-1)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (2.27e-1)" "unprognostic (2.83e-2)" "unprognostic (1.11e-1)" 0.3 0.1 0.0 2.6 0.0 5.0 0.6 0.0 0.1 0.4 0.0 2.9 2.5 0.5 0.1 2.4 0.1 0.5 0.1 0.1 0.0 0.0 0.4 0.2 4.8 0.0 0.1 0.0 0.0 0.2 0.0 3.2 0.1 2.1 3.5 0.0 0.3 0.1 0.0 1.6 2.4 1.5 0.0 0.6 1.2 8.1 0.2 8.1 0.3 0.2 4.8 0.9 0.7 0.2 47.2 21.5 40.0 18.5 2.5 5.6 31.3 58.9 26.9 49.1 42.1 17.9 19.3 0.0 42.8 24.4 78.6 30.8 58.6 30.7 82.4 41.2 38.2 38.3 35.9 10.5 0.6 33.4 0.0 2.1 1.6 56.3 31.2 10.0 36.0 16.5 26.6 36.1 88.3 10.7 0.1 12.5 34.6 19.5 28.9 0.0 118.7 15.3 19.8 12.7 44.8 20.7 59.0 24.9 30.3 25.6 22.5 16.6 21.3 31.5 35.5 56.0 69.2 22.5 52.2 0.5 29.7 11.4 65.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 3.3 0.8 3.3 1.2 0.4 1.3 1.8 0.8 0.0 0.5 1.8 0.0 20.6 0.4 2.1 0.0 0.2 44.9 4.0 1.6 1.6 0.0 31.8 0.5 0.0 35.2 4.4 8.2 2.0 0.0 17.5 2.2 1.2 8.6 0.0 2.2 5.3 4.1 3.5 1.0 73.0 0.3 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 6.9 2.2 0.5 0.1 0.9 0.2 0.0 0.6 4.0 86.8 19.6 12.2 1.3 2.9 1.6 0.5 8.8 1.7 DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.2;tongue: 122.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Glandular and luminal cells: 66.1;Oligodendrocytes: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cell line enhanced" "Detected in many" "Daudi: 105.1;RPMI-8226: 193.2;RPTEC TERT1: 149.3;U-698: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: AB_1847606, HPA023945: AB_1847607, HPA024011: AB_1847608" "unprognostic (3.41e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-2)" "unprognostic (1.15e-2)" "unprognostic (3.19e-1)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-1)" "unprognostic (2.49e-2)" "unprognostic (3.24e-2)" "unprognostic (6.02e-2)" "unprognostic (7.29e-2)" "unprognostic (5.66e-2)" "unprognostic (1.02e-1)" "unprognostic (4.16e-2)" "unprognostic (2.84e-2)" 14.4 52.8 12.0 3.0 16.7 2.0 20.7 12.6 11.9 39.2 3.8 23.3 16.9 16.5 11.1 15.2 27.1 10.8 5.1 9.7 23.2 40.0 16.3 5.3 10.1 15.8 12.5 24.7 11.9 16.9 11.4 4.9 15.3 12.1 9.9 2.0 106.3 15.6 158.2 6.6 14.5 15.5 14.8 9.5 40.0 2.9 16.3 5.1 98.0 122.3 2.9 5.6 7.0 24.2 0.1 3.5 0.3 1.1 21.0 6.2 0.3 0.1 0.3 0.6 0.5 2.4 0.4 105.1 2.3 1.2 0.3 0.3 5.4 0.2 0.4 2.3 2.7 14.2 0.9 0.6 12.8 3.0 23.7 5.5 9.5 0.8 0.6 0.1 0.0 1.8 0.1 16.9 0.3 7.1 0.1 2.5 1.3 45.5 3.7 0.4 4.9 193.2 149.3 4.1 3.2 0.7 1.7 11.0 3.2 2.8 9.6 0.5 0.0 0.4 0.9 21.4 0.5 45.4 11.4 55.2 6.5 3.9 0.6 0.0 0.9 0.0 0.2 1.7 0.8 0.1 0.4 0.7 20.3 0.1 0.8 0.6 0.3 0.4 0.2 1.0 0.4 1.0 12.0 16.7 12.6 11.9 9.7 23.2 15.8 12.5 15.3 14.8 16.3 24.2 23.1 6.4 9.3 4.9 2.9 5.2 15.4 3.8 27.3 2.1 16.5 10.4 2.4 15.7 8.4 25.8 0.0 0.6 0.8 2.7 86.1 5.7 2.2 19.0 9.7 7.5 16.7 12.4 14.5 11.8 4.1 10.0 29.6 66.1 12.0 5.4 2.5 12.7 3.3 0.0 31.0 7.7 0.0 16.0 39.5 2.2 11.8 14.9 14.2 46.9 1.5 1.2 2.1 9.5 123.9 1.1 36.5 3.4 6.4 7.1 21.0 33.6 1.1 0.7 0.0 8.1 5.7 3.6 3.8 16.5 5.5 0.4 1.3 6.0 16.5 21.9 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 84000 "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000873: AB_1847632" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (4.03e-2)" "unprognostic (1.33e-2)" "unprognostic (6.28e-2)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.86e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.72e-7)" "unprognostic (3.63e-2)" "unprognostic (2.29e-1)" "unprognostic (6.27e-2)" "unprognostic (6.28e-3)" 25.3 28.6 45.7 14.9 40.4 7.4 26.4 34.6 48.9 30.0 24.7 34.0 26.2 32.9 12.9 46.5 27.7 19.0 33.6 44.1 42.8 31.1 30.6 28.6 16.8 45.2 43.3 35.9 44.6 26.3 33.1 16.4 43.6 34.7 16.0 9.1 33.7 23.5 27.2 61.3 28.8 15.6 38.3 25.5 30.2 25.3 52.0 16.7 39.8 19.5 12.5 31.2 32.1 38.6 43.2 26.5 32.6 58.3 57.9 23.2 31.8 28.3 34.8 27.2 26.8 45.7 47.9 22.7 38.7 30.7 19.4 79.7 24.2 27.2 11.4 19.4 44.4 15.3 16.0 37.0 35.1 28.8 33.4 33.3 61.6 21.1 24.3 23.4 30.3 14.2 115.6 19.3 14.0 45.0 15.2 31.0 27.3 67.8 19.1 26.5 34.4 8.9 46.2 46.8 44.4 32.8 52.1 36.0 32.6 17.6 33.5 25.9 27.0 50.0 25.6 26.3 23.1 21.5 8.5 14.9 23.7 16.5 38.9 9.5 10.3 16.5 6.1 5.3 5.3 4.3 6.5 6.1 6.8 4.7 7.8 6.4 23.5 4.6 3.9 4.0 9.5 11.3 45.7 40.4 34.6 48.9 44.1 42.8 45.2 43.3 43.6 38.3 52.0 38.6 16.4 19.2 27.0 34.3 10.0 9.7 10.8 17.1 17.6 30.1 23.4 20.6 18.0 30.0 23.3 27.6 14.6 17.2 9.5 59.7 0.0 24.9 13.7 9.6 11.2 13.7 19.9 4.2 35.7 21.9 19.0 13.5 27.0 16.9 8.2 24.5 21.4 27.3 12.1 37.0 43.7 30.3 18.3 18.5 4.7 22.2 17.1 10.4 8.8 22.5 16.4 18.5 11.3 54.8 32.6 30.9 24.0 22.6 11.1 18.8 27.7 10.6 14.0 23.0 13.1 14.4 15.1 12.6 12.9 22.1 12.4 10.8 11.8 17.7 28.4 16.8 DHCR7 SLOS ENSG00000172893 "7-dehydrocholesterol reductase" Q9UBM7 11 71428193-71452868 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 77.9;Granulosa cells: 81.3;Hepatocytes: 156.1;Theca cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044280 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "HPA044280: AB_10794893" "unprognostic (1.76e-1)" "unprognostic (1.50e-3)" "unprognostic (1.32e-2)" "unprognostic (7.16e-3)" "unprognostic (2.69e-1)" "unprognostic (2.18e-3)" "unprognostic (8.57e-3)" "unprognostic (3.02e-2)" "unprognostic (4.91e-2)" "unprognostic (1.13e-1)" "unprognostic (1.08e-2)" "unprognostic (5.45e-2)" "prognostic favorable (6.93e-7)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "prognostic unfavorable (5.67e-4)" 23.7 97.2 28.1 13.0 35.4 46.7 36.3 42.4 37.0 16.2 15.6 21.1 48.1 10.6 59.2 42.2 12.5 8.9 28.8 28.8 35.8 16.3 161.1 21.8 6.0 55.3 38.8 54.4 16.6 24.4 18.4 8.3 55.8 21.6 14.4 8.7 27.8 7.1 13.6 68.2 19.3 9.9 34.4 9.6 19.1 31.0 38.0 4.7 11.9 13.2 9.4 7.9 22.7 58.9 126.4 112.3 106.7 118.9 49.0 75.8 33.7 50.9 134.1 43.1 114.5 419.8 401.5 87.1 79.0 48.6 376.2 235.9 128.8 276.7 44.5 33.5 98.7 33.4 89.3 183.1 127.8 63.7 15.6 89.2 122.1 159.3 108.4 34.6 63.8 112.7 159.6 180.7 43.2 341.1 52.4 72.6 154.1 124.9 67.4 46.9 150.6 377.3 162.3 187.3 144.7 53.9 48.4 157.6 113.9 51.4 153.2 34.5 60.4 11.5 62.4 3.7 61.5 59.3 78.7 95.8 33.8 110.9 48.9 5.6 2.1 1.9 10.5 1.4 12.6 6.5 8.9 9.8 2.8 5.4 11.0 13.0 1.1 5.8 1.5 7.1 6.0 6.9 28.1 35.4 42.4 37.0 28.8 35.8 55.3 38.8 55.8 34.4 38.0 58.9 7.1 3.2 19.1 7.2 7.1 0.8 10.1 77.9 3.4 8.4 21.8 14.9 13.1 15.7 39.2 22.0 12.5 15.5 11.9 9.9 7.9 36.9 0.1 3.9 1.5 11.8 9.5 5.2 3.2 49.9 27.6 12.8 11.7 9.3 0.0 81.3 7.9 156.1 11.9 0.0 4.5 12.3 54.9 3.8 3.3 1.7 8.4 5.6 5.4 1.0 5.8 21.2 4.1 5.0 14.7 26.7 11.5 4.9 10.0 16.5 8.9 3.8 7.6 8.7 13.1 3.9 9.0 0.5 7.0 11.9 1.1 54.2 13.8 103.6 15.0 9.5 DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 323.7" "Cell type enhanced" "Detected in many" "Late spermatids: 409.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 86.8;MAIT T-cell: 63.1;memory CD4 T-cell: 46.9;memory CD8 T-cell: 41.0;myeloid DC: 24.0;naive CD4 T-cell: 79.2;naive CD8 T-cell: 50.1;NK-cell: 41.1" "Group enriched" "Detected in many" 5 "dendritic cells: 24.0;NK-cells: 41.1;T-cells: 86.8" "Cell line enhanced" "Detected in many" "A549: 107.4;CAPAN-2: 206.9;hTERT-RPE1: 196.7;SK-BR-3: 104.6;WM-115: 192.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli, Mitochondria" "HPA010844: AB_1847653" "unprognostic (7.83e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-2)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.25e-3)" "unprognostic (5.06e-2)" "unprognostic (3.40e-2)" "unprognostic (5.18e-2)" "unprognostic (1.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.80e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "prognostic favorable (2.65e-4)" "unprognostic (5.48e-2)" 150.9 21.6 38.3 18.6 37.8 13.8 115.8 34.8 41.1 89.8 96.3 60.8 50.2 34.6 25.3 117.1 53.9 33.5 73.2 38.0 38.0 87.8 323.7 56.4 18.0 57.2 37.8 38.8 108.4 31.3 48.8 19.6 40.1 169.6 21.2 8.6 67.0 48.2 76.2 71.9 52.5 16.8 40.6 27.0 87.1 20.2 41.3 10.4 121.2 24.7 8.9 73.0 107.0 44.2 18.1 107.4 0.1 42.7 54.9 5.0 11.9 6.2 0.3 0.2 0.4 11.8 206.9 0.1 5.2 57.7 17.6 79.9 21.4 10.6 0.2 0.1 36.3 16.5 11.3 57.3 8.5 0.3 0.3 27.9 13.5 0.3 0.5 196.7 18.0 0.7 24.3 0.3 0.3 3.0 4.4 1.0 6.8 18.5 40.3 0.5 0.1 20.2 0.1 36.6 1.3 2.0 35.0 104.6 6.6 13.2 10.3 4.8 13.5 0.5 2.2 30.3 0.4 3.3 0.2 0.2 23.9 1.4 192.8 9.2 0.8 0.1 86.8 0.5 63.1 0.6 46.9 41.0 24.0 0.7 79.2 50.1 4.7 41.1 1.1 3.0 1.4 48.2 38.3 37.8 34.8 41.1 38.0 38.0 57.2 37.8 40.1 40.6 41.3 44.2 139.5 96.1 55.9 26.8 3.4 25.6 136.0 114.8 59.2 2.0 17.5 22.6 42.3 45.8 93.4 20.2 18.8 34.4 35.5 83.8 23.5 99.3 99.6 69.8 50.2 54.1 25.1 23.6 3.7 163.1 45.0 56.4 32.1 83.7 15.8 2.6 73.5 181.3 67.1 0.0 3.3 33.0 42.7 69.6 8.4 409.5 22.7 43.6 7.2 17.8 11.5 15.3 38.1 1.0 0.6 129.6 69.5 9.8 3.5 76.2 112.6 52.9 82.8 2.4 0.0 10.5 30.8 1.9 1.4 51.7 27.0 26.3 28.3 7.9 33.0 156.8 DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 615.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 840.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 199.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Mitochondria" "HPA031121: AB_10600803, HPA078401: " "prognostic favorable (6.42e-4)" "unprognostic (5.20e-2)" "unprognostic (6.70e-3)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (4.65e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "prognostic favorable (1.92e-10)" "unprognostic (8.35e-3)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" 62.1 103.4 50.8 43.8 53.9 61.0 58.5 59.2 75.4 48.9 50.2 73.0 108.9 49.8 96.5 44.3 45.9 59.1 47.1 49.9 55.1 100.5 146.4 64.2 45.5 62.3 54.9 64.9 76.8 226.8 54.7 29.6 63.3 409.9 69.5 111.1 317.5 134.6 615.8 46.6 181.0 51.0 57.8 45.4 182.3 9.8 52.0 39.2 120.3 136.0 49.4 51.7 41.1 65.6 221.3 52.9 41.8 89.3 219.6 74.4 42.8 74.3 186.4 26.5 59.0 37.3 149.8 21.5 41.7 76.8 78.0 92.7 57.2 108.3 34.5 156.1 36.0 53.7 28.7 60.9 110.1 71.8 1.7 63.3 116.7 47.6 153.0 50.8 52.5 66.2 18.2 52.6 61.4 59.2 40.9 67.2 18.6 151.2 55.4 42.7 50.8 24.4 118.3 70.5 83.4 99.8 72.6 118.0 168.2 52.7 72.7 32.5 35.8 126.6 38.7 36.9 44.2 18.3 7.9 45.0 62.6 64.8 93.5 743.5 213.1 519.6 335.7 159.1 340.6 184.4 238.9 298.5 185.0 167.0 134.6 258.5 835.4 294.7 224.0 388.8 215.5 450.2 50.8 53.9 59.2 75.4 49.9 55.1 62.3 54.9 63.3 57.8 52.0 65.6 109.6 54.5 102.5 16.0 72.2 34.0 70.3 233.2 52.3 25.7 81.2 57.4 27.6 160.2 138.4 86.5 83.4 29.6 210.4 101.3 19.6 222.5 2.1 56.2 55.5 89.7 46.5 20.4 12.2 165.9 88.7 87.9 120.8 120.0 178.5 22.9 48.5 166.4 94.4 42.1 19.0 102.2 386.6 54.5 70.6 3.5 82.3 98.7 108.5 16.9 172.5 94.4 299.7 26.2 20.1 210.6 114.5 84.2 99.0 263.4 840.4 44.1 57.0 70.7 85.5 66.4 73.7 1.6 2.9 47.0 25.4 20.8 152.1 19.7 79.2 47.1 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIRAS2 "Di-Ras2, DKFZp761C07121" ENSG00000165023 "DIRAS family GTPase 2" Q96HU8 9 90609832-90642862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 72.5;retina: 39.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 105.3;Excitatory neurons: 103.0;Horizontal cells: 70.7;Oligodendrocytes: 25.9;Rod photoreceptor cells: 23.9" "Group enriched" "Detected in many" 4 "glioma: 5.7;renal cancer: 5.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.5;EFO-21: 2.4;SCLC-21H: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.70e-1)" "unprognostic (6.02e-2)" "unprognostic (1.20e-3)" "unprognostic (4.39e-2)" "unprognostic (1.35e-1)" "unprognostic (6.57e-2)" "unprognostic (4.27e-5)" "unprognostic (3.94e-2)" "unprognostic (4.37e-2)" "unprognostic (9.75e-3)" "unprognostic (9.85e-3)" "unprognostic (1.86e-1)" "unprognostic (5.70e-2)" "unprognostic (2.14e-1)" "unprognostic (5.39e-1)" "unprognostic (2.64e-3)" "unprognostic (2.05e-1)" 0.2 2.9 38.2 0.2 44.5 0.5 0.8 72.5 67.8 9.2 0.0 0.4 2.3 0.4 0.4 0.1 0.6 5.1 0.1 51.3 3.5 0.9 0.5 0.2 0.4 0.1 7.3 0.1 1.3 4.0 0.9 0.7 1.2 0.1 0.2 39.5 2.1 0.4 0.1 0.9 2.5 0.3 0.0 0.4 1.3 0.3 9.4 0.2 2.8 0.0 0.1 0.1 0.0 58.6 0.0 0.8 7.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.2 0.2 0.0 0.1 1.5 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.3 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.2 0.1 0.1 0.0 0.0 38.2 44.5 72.5 67.8 51.3 3.5 0.1 7.3 1.2 0.0 9.4 58.6 0.1 0.0 0.0 9.8 0.0 0.1 0.0 0.0 0.0 105.3 2.3 1.0 0.5 7.2 0.1 3.7 2.1 0.0 0.0 0.0 0.0 2.0 0.2 6.7 0.8 0.4 0.0 0.0 103.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.9 0.0 70.7 21.8 0.0 0.0 0.0 0.3 0.1 0.9 0.0 1.8 13.1 0.0 10.3 0.0 21.6 25.9 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 23.9 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 DISP2 "C15orf36, DISPB, HsT16908, KIAA1742, LINC00594" ENSG00000140323 "Dispatched RND transporter family member 2" A7MBM2 15 40358219-40378621 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 17.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.0;Distal enterocytes: 16.8;Horizontal cells: 18.5;Intestinal goblet cells: 18.2;Proximal enterocytes: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 4.2;HaCaT: 6.6;SCLC-21H: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059903 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA059903: AB_2684156" "unprognostic (3.43e-4)" "unprognostic (7.65e-3)" "unprognostic (4.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (3.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" "unprognostic (4.47e-8)" "unprognostic (1.96e-1)" "unprognostic (3.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.71e-1)" 0.2 0.7 5.1 0.4 4.7 0.3 0.1 17.6 5.7 0.3 0.0 1.5 1.1 0.2 0.1 0.1 0.2 0.2 0.1 3.6 3.9 0.0 0.1 0.1 0.4 5.5 1.6 0.3 0.3 0.1 1.3 0.2 5.8 0.1 1.2 1.6 0.3 0.4 0.1 0.3 1.2 0.3 0.4 0.2 1.2 0.7 4.5 0.2 1.4 0.0 0.0 0.1 0.1 1.9 1.3 0.5 0.3 2.0 0.1 0.0 0.7 0.2 0.1 0.8 1.2 1.9 0.6 0.2 1.3 0.8 4.2 6.6 0.2 1.1 0.5 0.1 0.4 0.3 0.4 0.1 0.0 0.4 1.1 1.4 0.0 0.2 0.1 0.2 0.4 0.7 0.5 0.8 1.1 0.3 0.2 0.3 0.3 1.7 0.9 0.2 0.3 0.4 0.2 1.7 13.4 1.9 0.2 0.1 0.2 0.3 0.3 0.2 0.4 0.9 0.7 0.2 0.2 0.2 0.1 0.2 0.3 0.5 1.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.0 5.1 4.7 17.6 5.7 3.6 3.9 5.5 1.6 5.8 0.4 4.5 1.9 0.9 3.2 3.6 1.0 0.5 0.0 1.9 0.0 0.0 19.0 0.8 1.3 1.7 1.5 4.4 3.7 10.4 0.2 0.2 16.8 0.0 0.4 1.3 0.3 0.6 1.4 9.6 2.7 5.1 0.4 0.3 1.6 5.1 0.5 8.8 0.4 0.4 0.4 1.0 18.5 7.0 18.2 0.0 0.6 0.0 1.8 1.2 1.1 0.0 1.0 0.3 2.3 4.1 4.0 0.3 0.3 3.2 0.0 0.3 1.2 12.1 0.2 2.2 7.6 0.0 3.1 0.8 4.1 6.1 0.0 0.0 0.3 1.1 0.8 8.6 1.1 DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 422.9;Oligodendrocytes: 1542.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016307, HPA069593" Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Plasma membrane" "CAB016307: AB_2092015, HPA069593: " "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.79e-2)" "unprognostic (4.56e-3)" "unprognostic (3.54e-2)" "unprognostic (8.56e-2)" "unprognostic (8.90e-3)" "unprognostic (2.97e-1)" "unprognostic (5.98e-2)" "unprognostic (2.33e-1)" "unprognostic (2.41e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-3)" "unprognostic (3.56e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (3.07e-1)" 20.7 14.5 26.4 14.7 57.0 16.2 18.4 33.2 36.4 23.8 15.4 24.2 24.0 19.7 11.6 37.6 16.1 17.1 19.4 25.4 29.3 27.6 25.9 18.0 14.7 36.9 43.3 23.3 17.2 31.7 14.4 21.3 34.8 15.9 26.3 38.8 20.2 18.6 25.2 18.8 25.4 21.2 19.9 13.0 22.9 15.5 50.3 27.1 43.3 28.2 20.6 20.3 20.5 73.5 128.0 20.0 40.3 75.7 34.2 36.2 40.7 52.2 46.2 49.2 59.0 60.4 59.8 41.5 127.1 47.7 95.7 86.4 39.3 76.4 97.7 10.9 22.5 35.2 31.1 40.5 35.2 35.0 33.3 27.8 43.3 49.1 101.3 163.1 64.8 32.2 26.7 51.4 125.6 41.5 51.3 12.9 35.3 71.1 35.4 26.7 51.6 26.8 51.9 55.3 19.7 32.3 72.9 49.5 49.4 46.7 108.8 26.0 62.5 127.5 33.5 36.1 79.9 76.0 50.6 50.6 50.3 51.8 40.0 2.5 0.7 1.2 0.8 0.7 1.3 1.6 1.3 0.9 0.8 1.2 1.3 1.3 2.4 1.1 0.4 1.1 1.0 0.8 26.4 57.0 33.2 36.4 25.4 29.3 36.9 43.3 34.8 19.9 50.3 73.5 24.0 25.6 25.7 113.3 28.5 53.3 52.3 45.5 40.5 42.0 29.6 23.0 25.6 35.8 44.6 49.7 95.9 48.9 25.2 72.4 5.9 22.8 12.9 51.8 37.4 28.1 28.9 17.5 422.9 20.2 19.5 27.7 51.5 68.5 12.0 29.9 27.8 54.6 14.9 37.0 117.8 34.4 28.5 26.4 26.0 19.2 28.6 19.2 37.4 165.8 18.3 71.9 43.3 257.3 1542.2 30.3 48.0 25.6 34.1 52.3 50.6 20.8 66.3 101.7 13.1 40.5 25.5 31.2 37.9 66.7 70.8 25.0 30.6 29.3 38.8 106.8 DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 29.7;lymphoid tissue: 42.0;testis: 17.4" "Cell type enhanced" "Detected in many" "Erythroid cells: 92.6;Extravillous trophoblasts: 23.1;Plasma cells: 22.1;Spermatocytes: 68.1;Spermatogonia: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA005546 Enhanced Supported "Centriolar satellite,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Centriolar satellite, Cytosol" "HPA005546: AB_1078677" "unprognostic (2.24e-1)" "unprognostic (1.77e-1)" "unprognostic (1.19e-3)" "prognostic unfavorable (4.59e-4)" "unprognostic (1.42e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.52e-6)" "prognostic unfavorable (7.85e-4)" "unprognostic (6.15e-3)" "unprognostic (3.55e-1)" "prognostic unfavorable (9.94e-6)" "unprognostic (4.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.06e-2)" "unprognostic (3.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.93e-2)" 0.8 0.3 1.4 8.1 0.9 29.7 1.4 0.4 1.8 0.8 0.6 5.5 5.0 1.3 0.1 5.2 0.4 0.8 0.2 1.0 1.7 0.2 0.7 0.7 17.9 0.7 1.0 0.2 0.1 0.2 0.0 4.1 0.8 0.2 6.7 0.1 0.8 0.1 0.1 3.1 4.6 2.7 0.3 2.6 3.0 17.4 1.1 42.0 0.4 0.0 18.7 2.0 1.5 3.8 144.8 56.8 140.6 63.7 3.3 13.4 43.8 80.3 52.7 115.3 109.3 45.9 75.8 82.1 44.2 46.9 47.4 85.6 91.5 64.0 150.5 101.9 45.7 84.4 49.9 39.3 0.4 82.7 49.3 2.8 2.2 54.8 27.0 18.9 129.0 82.5 70.5 79.8 109.3 69.2 105.0 42.7 72.6 63.3 57.3 80.8 137.9 39.0 37.9 45.2 71.7 40.7 84.8 31.7 30.8 60.6 71.6 31.6 49.6 52.4 133.3 50.6 94.6 19.4 44.9 108.9 35.9 59.6 83.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.9 1.4 0.3 0.0 0.2 0.1 0.2 1.0 0.0 0.0 5.4 0.7 1.4 0.9 0.4 1.8 1.0 1.7 0.7 1.0 0.8 0.3 1.1 3.8 0.1 0.0 0.5 0.0 4.4 1.1 0.7 3.3 0.0 0.0 1.2 0.9 0.4 0.0 1.3 0.0 0.0 11.6 1.4 3.2 0.0 0.4 19.7 7.2 2.6 2.4 0.0 92.6 0.3 0.0 23.1 4.2 7.7 4.5 0.0 15.8 3.9 0.5 10.5 0.0 0.3 3.6 8.2 4.1 1.6 6.0 0.9 3.7 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.2 1.2 22.1 0.6 0.3 0.1 1.3 0.0 6.6 0.0 3.8 68.1 31.7 11.6 0.4 1.9 4.0 0.9 6.9 1.4 DMAC1 "C9orf123, MGC4730, TMEM261" ENSG00000137038 "Distal membrane arm assembly complex 1" Q96GE9 9 7796500-7888380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 500.8;Hofbauer cells: 221.7;Proximal tubular cells: 254.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA014585 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 7: Non-specific - Mitochondria" "HPA014585: AB_1845803" "unprognostic (1.48e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-3)" "prognostic favorable (4.15e-4)" "unprognostic (2.78e-2)" "unprognostic (2.79e-3)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-2)" "unprognostic (3.26e-3)" "unprognostic (3.65e-1)" "prognostic favorable (1.96e-11)" "unprognostic (1.75e-1)" "unprognostic (4.19e-1)" "unprognostic (2.35e-1)" "unprognostic (7.41e-2)" 10.6 11.9 16.8 7.7 17.0 6.2 12.4 17.5 21.0 9.3 9.0 12.6 9.8 10.0 11.8 9.3 11.0 6.3 25.4 16.3 17.8 15.9 10.2 7.2 10.0 15.2 15.0 13.2 9.2 21.8 12.3 8.1 15.6 11.9 9.9 9.0 14.3 11.6 43.1 8.5 9.1 8.1 15.1 10.4 10.7 7.0 16.0 20.6 11.8 29.8 8.9 11.5 8.3 16.9 18.5 21.8 19.7 12.3 15.4 19.1 13.3 11.0 7.7 11.5 10.4 9.9 11.3 27.1 5.6 9.8 15.0 9.8 21.2 18.8 11.6 16.2 24.3 49.3 32.7 31.8 15.6 17.2 6.7 24.1 13.2 9.1 13.9 10.6 11.0 24.3 9.2 5.6 12.2 15.7 25.1 39.7 17.5 15.6 10.5 19.0 11.1 16.4 13.2 17.6 31.5 17.6 12.0 8.0 14.1 13.5 10.5 10.5 14.0 8.8 14.2 11.6 7.7 7.0 12.0 14.5 7.4 14.3 9.0 2.0 10.1 4.5 11.5 12.2 17.4 26.5 15.7 12.3 12.6 22.5 20.5 16.5 1.6 20.8 9.8 13.1 19.9 19.6 16.8 17.0 17.5 21.0 16.3 17.8 15.2 15.0 15.6 15.1 16.0 16.9 42.2 70.5 48.5 0.0 15.7 0.0 0.0 0.0 0.0 0.0 69.5 81.5 0.0 0.0 24.1 101.2 0.0 113.6 13.9 0.0 500.8 94.2 0.0 81.4 64.3 30.0 0.0 0.0 0.0 90.7 96.3 32.8 0.0 58.6 27.8 127.7 0.0 0.0 221.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 62.4 0.0 0.0 3.1 0.0 0.0 254.7 70.7 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 55.4 17.3 79.3 0.0 0.0 DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Distal tubular cells: 15.6;Glandular and luminal cells: 14.5;Hepatocytes: 30.8;Proximal tubular cells: 29.2;Squamous epithelial cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.3;hTERT-RPE1: 7.4;LHCN-M2: 2.9;RPTEC TERT1: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.2" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA044764: AB_10959788, HPA062253: AB_2684726" "unprognostic (1.47e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.67e-3)" "unprognostic (4.36e-2)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.64e-2)" "unprognostic (3.65e-3)" "unprognostic (2.92e-1)" "prognostic favorable (1.14e-6)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (8.53e-3)" 1.8 0.0 0.4 0.2 0.4 0.0 0.4 0.3 0.3 1.6 2.4 0.4 0.6 0.3 1.2 1.7 0.3 0.9 0.3 0.6 0.3 3.4 8.4 0.9 0.4 0.4 1.6 0.2 1.4 2.2 0.7 0.0 0.4 1.4 0.3 0.1 3.5 0.4 0.7 0.2 0.5 0.1 0.4 0.2 2.0 0.1 0.7 0.5 1.8 1.1 0.8 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.2 0.1 0.1 0.0 6.3 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.2 1.2 1.7 0.2 0.0 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 7.4 0.4 0.0 0.0 2.3 2.9 0.6 0.0 0.0 1.2 0.3 2.1 0.0 0.1 0.9 3.0 0.0 0.1 0.0 0.8 0.5 1.4 1.4 0.0 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.6 0.3 0.4 1.6 0.4 0.4 0.7 0.4 0.1 0.0 2.7 2.0 0.1 0.0 4.8 7.2 19.4 0.5 1.9 1.0 1.9 5.7 5.6 5.5 0.0 0.0 0.0 1.1 15.6 6.9 0.1 10.7 1.4 0.3 2.4 0.0 0.0 6.7 0.0 0.8 10.2 14.5 0.0 0.6 0.0 30.8 0.3 0.0 0.0 0.7 8.2 0.3 0.3 0.1 0.3 0.4 0.0 1.0 0.0 5.4 0.0 0.0 0.0 7.8 0.2 0.0 0.1 6.3 4.1 29.2 5.9 0.1 0.0 2.9 0.6 0.2 1.2 26.5 0.4 0.1 0.3 0.0 1.9 8.2 DNAJC19 "Pam18, Tim14, TIMM14" ENSG00000205981 "DnaJ heat shock protein family (Hsp40) member C19" Q96DA6 3 180983709-180989774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" Chaperone Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 471.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037782 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA037782: AB_10672611" "unprognostic (4.52e-2)" "unprognostic (3.55e-3)" "unprognostic (3.08e-2)" "unprognostic (2.45e-3)" "unprognostic (1.41e-1)" "unprognostic (5.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "prognostic favorable (8.53e-5)" "unprognostic (6.19e-2)" "unprognostic (1.76e-2)" "unprognostic (2.14e-2)" "unprognostic (1.75e-1)" "unprognostic (4.66e-1)" "unprognostic (3.33e-1)" "unprognostic (4.20e-3)" 22.7 44.1 26.1 11.1 27.1 10.8 26.4 27.2 39.7 19.4 28.8 27.5 21.4 18.9 33.0 22.9 21.3 11.8 73.4 27.2 28.0 50.2 48.9 14.7 16.3 26.4 29.3 26.5 27.9 34.7 30.9 14.2 26.3 22.6 17.7 27.2 28.1 18.2 65.8 15.0 18.1 11.8 27.6 18.5 26.2 11.6 26.8 20.7 25.6 77.8 13.4 23.5 18.4 28.1 53.9 14.0 38.8 29.6 45.6 27.0 35.4 30.2 18.2 29.1 25.5 49.0 26.2 23.0 63.9 25.5 70.9 26.8 37.8 36.5 35.9 36.5 49.1 27.0 24.5 48.3 48.9 64.9 27.5 25.9 29.8 24.4 43.0 37.9 34.0 55.2 42.8 35.8 23.0 44.2 48.5 54.6 51.2 75.9 44.8 31.4 26.9 69.6 43.3 24.8 38.7 20.6 30.8 75.8 82.3 44.0 85.2 45.2 16.8 18.5 27.1 26.3 54.4 47.7 60.7 80.1 19.0 49.9 22.9 33.6 20.4 31.5 33.3 22.3 39.8 34.7 38.5 34.7 28.6 29.8 39.8 40.6 4.4 26.8 27.3 36.4 35.0 30.8 26.1 27.1 27.2 39.7 27.2 28.0 26.4 29.3 26.3 27.6 26.8 28.1 68.3 38.5 52.5 11.1 66.3 56.6 68.6 105.4 56.9 31.7 138.6 183.0 151.7 120.1 70.1 77.3 14.6 116.6 67.4 57.9 471.6 83.9 9.1 57.4 50.4 61.4 45.2 48.8 18.7 109.3 111.2 71.7 30.1 42.7 110.7 79.7 68.6 167.0 68.0 48.8 20.5 90.7 91.6 35.5 59.8 13.2 85.1 42.8 74.7 9.4 58.6 91.4 74.2 13.0 21.4 79.9 66.1 72.6 47.7 91.5 101.0 216.8 58.7 67.6 85.5 80.3 108.8 82.1 56.3 73.9 60.1 68.7 68.4 121.4 86.7 69.2 DNAJC30 WBSCR18 ENSG00000176410 "DnaJ heat shock protein family (Hsp40) member C30" Q96LL9 7 73680918-73683453 "Disease related genes, Human disease related genes, Predicted membrane proteins" "ATP synthesis" Chaperone "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 120.1;Late spermatids: 230.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017318 Supported NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA017318: AB_1858788" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (2.66e-2)" "unprognostic (4.53e-1)" "unprognostic (3.93e-2)" "unprognostic (2.85e-3)" "unprognostic (4.60e-2)" "prognostic favorable (4.91e-8)" "unprognostic (1.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.51e-1)" "unprognostic (1.20e-2)" 6.4 14.7 7.2 3.1 7.9 2.9 6.3 7.1 8.3 5.5 5.5 6.0 3.8 7.1 4.6 5.4 6.4 2.0 11.3 7.9 7.1 9.7 11.9 3.9 3.5 7.0 6.9 6.2 7.9 6.6 10.5 2.7 7.2 6.6 3.2 3.8 6.1 4.7 9.3 5.0 5.2 2.9 5.1 6.0 6.3 12.5 6.9 3.7 8.7 4.8 2.9 6.2 4.4 7.2 6.5 6.3 4.6 9.2 7.0 4.9 4.8 10.0 7.3 7.6 7.4 6.1 6.6 5.7 2.5 8.0 11.2 9.0 4.1 5.6 4.3 6.7 8.4 3.3 6.0 6.5 7.2 5.6 4.5 5.5 4.6 6.9 5.9 5.3 6.6 7.3 6.8 5.0 7.5 13.0 9.1 11.3 3.9 6.0 10.6 6.2 3.6 14.1 9.9 7.5 12.3 6.6 10.2 17.7 7.9 4.6 16.1 3.7 6.5 8.0 5.8 8.4 7.2 5.3 3.9 5.4 6.4 3.8 10.0 5.4 6.2 3.9 6.3 5.7 7.7 7.4 7.7 7.6 6.0 9.8 9.1 7.8 0.8 6.0 4.4 6.3 5.6 5.2 7.2 7.9 7.1 8.3 7.9 7.1 7.0 6.9 7.2 5.1 6.9 7.2 10.0 19.2 6.2 2.3 14.7 5.9 16.6 19.9 12.5 34.9 13.9 11.9 19.7 14.3 15.8 18.4 14.6 43.6 18.6 7.2 56.7 30.2 120.1 15.9 13.3 10.6 17.4 6.9 5.6 28.0 16.2 13.9 16.3 11.3 12.7 20.8 15.0 25.3 22.3 20.2 6.1 12.8 12.2 13.2 5.3 230.1 24.5 9.3 14.2 2.8 26.9 24.6 32.0 2.5 8.9 19.2 8.4 18.4 9.4 13.3 15.4 81.8 10.0 29.5 19.7 12.6 12.4 69.6 16.5 16.9 8.2 36.0 11.2 56.0 17.1 12.6 DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 73.0;brain: 147.5;choroid plexus: 143.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 123.3;Inhibitory neurons: 333.0;Oligodendrocyte precursor cells: 435.8;Oligodendrocytes: 247.7" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "GAMG: 368.0;hTERT-HME1: 149.7;hTERT-RPE1: 409.5;U-138 MG: 252.2;U-87 MG: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" 2.0 73.0 88.3 1.3 121.0 0.0 2.3 139.7 82.9 2.0 143.8 5.2 0.4 2.8 5.7 0.3 4.1 0.2 11.8 72.3 130.9 11.2 0.1 1.0 0.3 121.3 121.0 0.6 0.9 8.9 30.3 0.4 117.8 1.9 1.1 60.5 43.4 0.4 0.8 10.3 1.6 1.2 124.7 0.1 10.7 1.0 147.5 0.5 0.1 0.5 1.2 0.8 1.1 137.2 0.4 1.9 3.9 0.3 0.6 0.5 0.0 0.2 1.4 8.6 2.6 0.0 1.1 0.0 0.4 0.1 368.0 0.1 0.3 1.2 4.3 0.0 0.1 0.0 12.4 0.0 1.4 0.0 0.1 2.6 9.3 6.5 149.7 409.5 0.0 0.0 0.0 0.3 2.3 0.1 0.0 0.0 2.5 0.2 14.0 0.1 1.6 0.0 14.6 0.0 30.3 2.5 0.8 0.1 0.8 0.4 0.1 0.0 0.0 252.2 0.0 8.5 39.7 0.0 0.0 0.0 149.6 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 88.3 121.0 139.7 82.9 72.3 130.9 121.3 121.0 117.8 124.7 147.5 137.2 0.1 0.0 0.0 68.9 0.0 0.4 5.9 1.9 1.8 123.3 1.6 0.6 12.2 0.0 1.4 3.7 14.6 0.0 0.0 0.0 1.9 0.2 7.3 4.1 1.5 0.6 28.7 0.0 24.1 1.3 0.2 4.3 0.0 6.7 0.0 1.6 0.0 0.0 0.1 11.8 333.0 0.0 6.1 0.0 0.8 1.9 5.9 0.9 19.6 8.4 0.1 52.0 0.0 435.8 247.7 0.3 0.0 6.0 0.0 4.5 0.0 1.2 34.1 55.0 0.0 0.1 0.8 1.2 1.1 0.5 0.0 0.1 0.2 0.6 0.1 0.5 DOCK5 FLJ21034 ENSG00000147459 "Dedicator of cytokinesis 5" Q9H7D0 8 25184689-25418082 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 86.0" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 789.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017719, HPA056837" Approved Enhanced Cytosol No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA017719: AB_1847820, HPA056837: AB_2683253" "unprognostic (2.16e-1)" "unprognostic (3.55e-3)" "unprognostic (1.25e-2)" "prognostic favorable (1.91e-4)" "unprognostic (8.44e-2)" "unprognostic (1.24e-1)" "unprognostic (2.61e-2)" "unprognostic (2.88e-2)" "unprognostic (1.69e-2)" "unprognostic (4.21e-2)" "unprognostic (4.18e-3)" "unprognostic (3.00e-1)" "prognostic unfavorable (1.18e-6)" "unprognostic (2.81e-1)" "unprognostic (3.07e-1)" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" 4.9 3.4 17.1 7.5 56.6 17.0 4.8 33.4 30.0 4.4 25.2 8.4 10.6 4.1 5.1 3.4 6.2 5.8 7.8 19.5 29.1 4.3 15.2 9.3 1.8 43.4 39.9 6.8 4.7 2.6 8.2 10.2 43.6 7.9 9.4 2.5 6.7 5.6 2.6 5.4 12.9 3.3 19.3 19.3 6.6 6.2 40.7 1.9 15.5 2.8 1.6 4.1 4.9 86.0 19.8 43.2 4.1 0.3 9.8 10.6 14.2 45.5 26.5 12.4 9.6 6.3 15.5 0.4 4.0 40.3 13.7 34.6 4.9 32.5 19.9 6.2 6.1 20.2 40.5 15.8 11.1 5.0 21.6 7.3 12.9 13.6 20.3 13.6 10.7 0.8 0.3 0.8 12.2 11.5 0.7 9.5 4.1 24.4 11.9 0.3 9.0 0.5 9.1 12.0 3.0 1.4 24.0 14.5 4.7 3.4 4.5 4.0 32.1 21.1 13.6 25.5 17.1 0.7 0.2 0.3 27.4 10.2 27.4 14.6 2.5 3.8 0.4 5.5 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.3 30.7 0.4 6.8 0.4 0.0 0.3 17.1 56.6 33.4 30.0 19.5 29.1 43.4 39.9 43.6 19.3 40.7 86.0 2.7 44.8 41.5 96.6 2.2 18.5 13.2 30.5 2.2 9.6 12.8 5.8 13.4 31.5 31.4 14.7 2.1 28.3 20.1 50.6 0.0 10.3 0.9 16.3 10.0 10.6 17.5 9.9 4.9 12.0 100.2 28.1 32.1 53.1 31.0 52.8 8.2 35.0 13.3 1.7 3.6 26.7 8.2 60.3 51.0 5.6 28.9 41.3 85.4 38.4 24.5 20.0 22.6 61.3 789.8 48.9 27.4 48.2 13.4 36.0 60.0 6.2 20.9 2.3 13.1 4.0 12.1 0.9 5.6 5.8 7.2 20.5 10.8 25.1 27.7 16.8 DPCD "DKFZP566F084, RP11-529I10.4" ENSG00000166171 "Deleted in primary ciliary dyskinesia homolog (mouse)" Q9BVM2 10 101570560-101609662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 132.4" "Group enriched" "Detected in many" 4 "Early spermatids: 579.4;Late spermatids: 1068.7;Respiratory ciliated cells: 329.7;Spermatocytes: 313.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 20.2;intermediate monocyte: 22.2;myeloid DC: 29.6;non-classical monocyte: 9.5" "Group enriched" "Detected in all" 14 "dendritic cells: 29.6;monocytes: 22.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036603, HPA036604" Enhanced Approved "Nuclear speckles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear speckles" "HPA036603: AB_2675212, HPA036604: AB_10673503" "unprognostic (1.22e-2)" "unprognostic (1.73e-3)" "unprognostic (4.66e-1)" "prognostic favorable (6.57e-4)" "unprognostic (1.90e-1)" "unprognostic (9.13e-2)" "unprognostic (4.00e-3)" "unprognostic (1.71e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.55e-2)" "unprognostic (2.70e-1)" "unprognostic (5.04e-2)" "unprognostic (3.83e-2)" "unprognostic (7.54e-2)" 10.5 18.7 35.1 8.7 37.2 11.8 19.4 31.5 42.0 21.8 55.1 17.3 6.8 16.7 41.3 20.4 73.3 15.5 29.6 37.4 39.1 30.9 10.4 14.0 6.2 36.2 37.1 23.5 14.7 49.3 49.5 10.6 36.5 16.1 13.5 55.8 21.2 15.7 19.2 13.2 7.1 18.0 33.3 4.5 14.4 132.4 39.7 6.6 33.0 18.3 8.2 14.4 14.9 33.4 97.1 53.4 37.9 77.2 35.2 61.7 15.6 44.5 53.6 59.4 55.1 38.8 51.4 9.0 74.6 42.7 25.2 54.0 55.4 65.3 61.2 23.0 57.5 11.3 49.8 56.7 20.3 58.8 8.1 42.3 54.8 72.0 56.1 153.7 50.8 14.0 32.4 12.6 45.1 122.9 0.0 48.1 28.7 26.9 41.6 0.0 51.8 20.5 92.6 25.3 37.1 63.3 36.5 23.4 31.3 34.1 71.2 23.9 35.5 27.3 24.9 55.7 62.3 37.9 45.9 16.9 94.7 13.7 11.7 0.0 20.2 1.0 1.8 22.2 1.7 1.3 1.4 1.4 29.6 0.7 1.5 1.8 0.9 1.6 9.5 4.1 0.6 8.1 35.1 37.2 31.5 42.0 37.4 39.1 36.2 37.1 36.5 33.3 39.7 33.4 6.9 35.3 12.4 4.9 2.1 9.7 29.5 89.2 9.6 16.4 25.4 29.5 33.7 30.0 56.6 49.7 18.8 24.6 0.9 10.5 95.9 63.3 579.4 136.5 23.5 11.1 23.9 14.1 7.7 27.5 16.7 21.2 10.2 20.2 1.3 19.2 11.4 10.9 24.0 11.8 6.2 12.5 52.9 4.4 14.6 1068.7 23.6 8.7 16.0 3.7 6.9 27.8 2.1 4.0 1.4 33.9 12.4 27.8 5.6 18.6 3.5 117.3 329.7 49.1 0.0 12.4 29.0 313.8 77.4 8.7 14.2 10.7 2.9 25.3 22.1 23.9 DPY30 "Cps25, HDPY-30, Saf19" ENSG00000162961 "Dpy-30 histone methyltransferase complex regulatory subunit" Q9C005 2 31867809-32039805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 388.8;Respiratory ciliated cells: 396.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043761 Supported Supported "Nucleoplasm,Golgi apparatus" NA NA 29000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA043761: AB_10960501" "unprognostic (2.76e-2)" "unprognostic (1.48e-1)" "unprognostic (2.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (4.14e-3)" "unprognostic (1.91e-1)" "unprognostic (7.87e-2)" "unprognostic (1.01e-3)" "unprognostic (1.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (2.70e-1)" "unprognostic (6.77e-2)" "unprognostic (2.79e-2)" "unprognostic (1.49e-1)" 40.2 75.2 66.9 34.3 68.6 31.4 61.3 72.1 84.4 53.2 73.6 50.9 43.4 38.3 78.3 60.2 90.5 42.4 46.7 68.4 73.6 79.1 84.8 44.1 51.8 71.6 71.5 42.7 48.1 58.3 50.9 43.9 73.6 57.3 46.4 33.3 64.6 47.0 48.8 49.7 44.4 37.4 73.2 36.1 46.8 22.6 69.1 52.3 81.6 45.4 49.3 51.8 50.0 77.5 201.8 136.8 100.8 78.1 86.7 128.8 134.9 102.1 90.8 81.2 79.5 197.2 158.3 123.2 102.2 90.8 148.3 79.9 93.1 118.6 88.1 146.4 149.5 110.8 89.7 225.5 76.5 114.3 66.8 87.4 135.6 87.4 76.9 109.1 130.4 55.1 132.5 85.3 125.6 219.4 128.8 228.9 139.2 184.3 140.5 104.0 118.9 155.7 144.2 137.1 162.5 115.9 101.2 141.1 143.6 118.2 98.3 82.1 100.5 73.9 119.1 69.2 125.4 99.9 161.3 166.2 77.6 123.2 91.7 177.6 101.0 150.8 95.5 99.9 116.5 165.9 133.5 119.4 100.5 135.6 118.1 112.0 117.3 105.8 112.8 91.5 200.3 130.6 66.9 68.6 72.1 84.4 68.4 73.6 71.6 71.5 73.6 73.2 69.1 77.5 65.7 51.3 61.5 10.1 61.7 98.0 107.7 233.5 53.5 17.9 110.5 135.1 71.3 80.1 140.8 103.0 0.0 190.2 41.0 84.2 283.7 114.3 64.5 388.8 59.7 62.9 92.1 55.5 16.0 117.2 252.4 63.1 44.4 107.3 46.9 65.1 63.1 102.7 123.5 21.9 17.7 107.6 175.0 65.4 67.2 18.5 72.4 58.7 65.8 13.1 106.8 50.8 55.6 13.6 26.7 125.7 117.8 88.0 40.6 130.5 138.4 296.7 396.4 26.8 85.5 52.4 108.4 65.7 57.4 72.0 122.6 138.7 67.3 67.7 109.0 127.5 DRAP1 NC2-alpha ENSG00000175550 "DR1 associated protein 1" Q14919 11 65919274-65921563 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 813.2;Suprabasal keratinocytes: 1015.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 1032.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006790 Uncertain Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Cytosol "HPA006790: AB_1078702" "unprognostic (1.69e-2)" "unprognostic (1.02e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.84e-2)" "unprognostic (4.06e-2)" "unprognostic (4.89e-3)" "unprognostic (5.58e-2)" "unprognostic (8.47e-2)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "unprognostic (3.82e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (4.70e-2)" "unprognostic (1.38e-1)" "prognostic favorable (4.96e-5)" "unprognostic (1.62e-1)" 87.4 86.4 119.0 71.0 120.8 96.8 80.3 121.2 162.8 91.0 103.7 104.4 56.1 89.3 27.9 107.5 74.0 34.9 129.2 120.3 132.4 75.0 76.2 75.1 71.0 119.9 119.6 67.4 73.3 62.6 81.2 43.1 121.5 73.1 21.1 25.1 58.3 48.0 197.1 112.5 62.9 40.2 118.1 85.6 69.9 173.1 120.7 96.6 118.9 78.5 39.2 84.2 83.4 131.6 578.7 226.8 108.3 200.0 99.9 195.3 75.9 634.9 273.2 344.1 223.6 85.6 302.7 142.2 277.3 420.3 395.5 222.7 42.7 292.0 138.2 187.7 70.1 173.4 103.8 85.4 186.0 145.8 228.2 123.7 126.6 365.8 246.7 191.4 142.2 138.9 78.5 223.6 377.4 301.9 255.0 263.6 167.5 73.1 575.9 216.3 107.1 305.4 113.6 82.3 122.2 137.7 149.6 137.8 348.9 46.1 188.2 104.8 413.0 470.1 461.4 1032.4 556.2 201.8 186.6 149.9 490.1 91.4 650.8 146.5 118.9 290.5 131.0 311.9 117.5 139.5 116.3 136.6 183.2 124.2 114.6 123.3 164.6 194.6 538.9 136.8 148.5 112.7 119.0 120.8 121.2 162.8 120.3 132.4 119.9 119.6 121.5 118.1 120.7 131.6 116.7 6.4 30.5 9.1 131.8 813.2 199.3 238.8 139.5 56.9 122.9 189.0 32.9 64.3 89.8 130.6 35.5 136.6 166.9 111.7 283.7 202.8 128.9 78.6 142.8 110.6 151.9 195.7 11.5 170.7 161.9 130.2 58.1 98.9 238.0 78.9 92.1 96.4 298.5 63.9 10.8 120.4 142.4 152.4 462.0 85.7 179.3 208.1 247.3 14.0 241.9 79.9 286.3 11.6 22.9 289.9 126.2 173.0 131.7 423.3 144.8 257.8 54.4 47.9 92.1 90.1 194.1 131.0 171.1 163.8 1015.8 174.4 197.2 107.1 125.0 425.3 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-aminoacyl-tRNA deacylase 2" Q96FN9 14 31446036-31457506 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001117 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA001117: AB_2666204" "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (5.74e-6)" 8.6 6.3 4.7 4.9 6.8 2.3 7.1 5.2 6.5 4.0 5.2 4.8 3.9 5.2 5.0 5.7 4.9 3.5 3.1 5.3 5.3 5.8 8.1 5.8 5.5 5.5 5.9 5.3 6.3 6.1 4.4 4.3 5.9 5.7 5.4 5.0 6.0 3.9 1.6 5.6 3.7 5.5 4.9 4.9 4.0 4.0 6.2 5.0 6.2 1.6 5.5 4.7 3.8 8.1 11.4 9.5 8.1 10.6 14.6 12.3 5.5 10.3 10.0 8.0 7.1 5.2 10.7 21.6 6.8 11.8 8.6 10.8 13.0 11.6 13.6 11.7 5.7 6.2 6.5 29.0 15.7 12.6 7.3 14.0 12.9 7.1 15.9 6.7 11.8 12.8 12.3 9.9 10.7 13.7 18.3 11.3 11.0 19.6 9.7 12.3 6.0 11.3 15.0 9.8 12.1 8.0 16.8 21.6 12.4 6.9 19.8 6.5 8.6 8.7 7.7 7.1 9.1 12.3 24.5 20.7 3.8 11.4 14.3 2.5 2.6 1.0 2.0 2.2 2.9 2.7 3.0 2.2 3.7 3.2 4.5 3.0 1.5 3.7 1.2 2.2 1.6 2.8 4.7 6.8 5.2 6.5 5.3 5.3 5.5 5.9 5.9 4.9 6.2 8.1 2.9 9.6 9.0 10.1 7.6 5.2 5.7 5.1 13.1 5.9 6.1 4.3 4.8 15.7 4.9 3.7 8.4 9.1 4.9 3.3 3.9 5.7 4.4 6.8 7.2 3.8 3.0 8.0 9.2 6.2 6.3 6.2 5.1 3.0 1.3 5.9 3.9 11.6 5.1 5.0 12.7 6.7 14.2 5.5 3.7 6.6 7.5 4.0 3.6 2.8 4.8 9.5 7.2 35.2 40.2 5.2 3.9 8.2 7.1 6.0 3.3 9.7 6.2 9.2 0.0 7.4 6.8 10.1 2.7 16.2 5.4 2.7 5.4 10.3 7.2 4.2 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 DYNLL2 "Dlc2, DNCL1B, MGC17810, RSPH22" ENSG00000264364 "Dynein light chain LC8-type 2" Q96FJ2 17 58083419-58095542 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 455.4;Late spermatids: 892.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039954 Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 1000000 "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039954: AB_2676771" "unprognostic (7.22e-2)" "unprognostic (7.76e-2)" "unprognostic (3.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.93e-1)" "unprognostic (3.72e-2)" "unprognostic (6.78e-2)" "unprognostic (2.91e-2)" "unprognostic (1.68e-1)" "unprognostic (1.10e-2)" "prognostic favorable (5.26e-4)" "unprognostic (1.24e-1)" "prognostic favorable (1.12e-12)" "unprognostic (2.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (7.02e-2)" 24.5 41.8 76.8 17.7 84.5 17.7 16.9 78.1 77.7 18.2 45.6 26.1 25.0 19.6 22.4 20.3 19.4 13.4 62.8 63.4 80.4 42.1 35.2 17.9 15.5 83.6 90.1 20.4 17.8 47.2 28.7 30.4 83.6 30.3 20.1 41.2 30.8 26.3 113.7 19.1 24.3 18.9 83.4 18.0 21.3 26.2 87.9 22.5 33.0 58.7 18.4 20.7 17.6 72.0 54.1 36.0 72.3 33.1 44.0 24.0 114.6 53.2 21.1 25.2 19.7 80.4 25.4 48.0 58.8 33.1 30.1 28.4 33.8 42.2 43.2 47.8 24.5 52.1 21.9 47.7 34.8 56.2 31.1 24.3 28.2 29.4 23.2 26.4 17.1 39.8 52.7 28.4 24.7 81.5 64.1 23.2 49.9 35.3 36.5 58.3 42.5 19.9 22.0 57.9 49.3 39.4 47.7 19.0 42.0 37.2 56.2 26.1 31.0 49.3 62.2 33.2 39.8 52.6 68.5 57.0 25.5 44.2 35.2 1.0 0.2 0.5 0.6 0.1 0.7 0.4 0.5 0.6 0.1 0.4 0.5 0.8 0.4 0.4 0.9 0.2 0.4 0.2 76.8 84.5 78.1 77.7 63.4 80.4 83.6 90.1 83.6 83.4 87.9 72.0 33.9 12.8 43.8 1.0 28.1 49.1 40.7 13.7 45.5 63.7 55.7 39.8 186.2 44.3 23.8 60.7 39.6 102.1 59.7 56.7 31.3 37.6 455.4 51.5 57.3 32.5 67.2 40.6 1.2 31.2 73.4 30.6 20.9 55.2 22.8 19.1 23.9 104.7 43.0 70.7 2.0 55.7 26.4 28.4 37.4 892.8 29.5 32.8 65.8 1.9 31.9 74.7 19.6 0.5 2.8 38.0 38.6 26.7 19.4 35.3 50.0 78.2 18.4 41.1 26.3 40.1 86.1 46.5 44.8 45.1 46.0 60.1 46.9 29.0 49.7 36.5 DYNLRB1 "DNCL2A, DNLC2A, ROBLD1" ENSG00000125971 "Dynein light chain roadblock-type 1" Q9NP97 20 34516414-34540958 "Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 781.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009845 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "CAB009845: AB_2093671" "unprognostic (2.23e-1)" "unprognostic (7.60e-3)" "unprognostic (5.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (6.44e-4)" "unprognostic (9.10e-2)" "unprognostic (3.41e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.11e-1)" "unprognostic (7.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.37e-2)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" 168.7 208.4 430.4 96.9 440.2 113.7 163.7 416.5 552.8 163.7 400.8 228.4 113.8 193.0 204.9 155.4 198.5 117.1 275.7 448.5 454.1 265.8 122.0 169.4 123.9 444.7 443.3 153.9 115.0 222.9 204.3 154.6 436.7 180.9 128.2 171.7 142.1 170.7 222.8 222.1 156.4 158.7 416.1 143.0 166.7 66.6 422.8 154.3 174.4 224.5 135.1 191.4 158.8 458.8 244.4 317.6 259.4 207.3 307.5 294.9 175.4 264.1 393.5 399.2 340.7 853.3 231.1 135.6 327.4 402.0 385.5 215.3 282.2 391.6 265.9 164.5 198.8 463.2 286.8 679.1 345.7 217.5 249.6 251.4 250.4 320.2 245.7 306.2 282.2 255.8 195.1 249.0 415.5 313.4 314.7 427.4 148.6 284.7 345.2 158.6 359.6 220.2 618.7 160.8 264.2 273.9 382.9 631.9 359.4 249.2 362.5 240.7 251.9 500.8 122.4 351.2 295.8 208.8 310.3 157.3 430.1 186.7 225.0 225.4 112.5 221.2 88.0 123.1 88.8 144.2 145.6 117.2 128.8 127.3 101.4 102.1 111.4 132.4 144.3 161.2 238.7 135.0 430.4 440.2 416.5 552.8 448.5 454.1 444.7 443.3 436.7 416.1 422.8 458.8 188.4 169.9 106.5 26.1 107.9 146.8 176.8 215.9 100.2 105.4 136.0 200.3 125.5 170.1 157.4 292.4 58.4 297.8 112.9 283.9 481.3 264.4 34.0 266.4 139.5 170.9 226.7 98.2 34.7 223.4 211.4 149.1 85.1 208.5 159.0 149.8 162.4 104.1 287.9 80.8 30.0 284.6 256.3 127.8 131.5 51.0 234.9 139.1 193.9 19.7 236.2 435.8 148.3 20.1 61.4 317.5 379.3 240.3 117.0 240.4 388.9 781.8 253.1 127.6 203.8 101.8 210.8 65.6 77.2 106.3 150.0 342.3 124.9 90.9 160.5 184.3 EARS2 "KIAA1970, MSE1, mtGlnRS" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23520754-23557731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA043289: AB_10963932, HPA043633: AB_10959901" "unprognostic (3.10e-2)" "unprognostic (1.60e-1)" "unprognostic (3.65e-3)" "unprognostic (4.20e-1)" "unprognostic (3.57e-1)" "unprognostic (4.64e-2)" "unprognostic (2.73e-1)" "unprognostic (2.91e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (8.09e-2)" "prognostic favorable (3.16e-6)" "unprognostic (2.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (4.29e-2)" 3.7 7.6 3.3 1.2 3.5 1.5 4.0 2.7 4.0 2.9 3.6 3.7 1.1 3.7 3.0 5.2 3.0 1.0 5.3 3.3 3.6 4.9 9.9 3.1 1.8 3.3 2.5 3.3 5.6 4.8 3.5 2.5 2.6 3.0 2.3 1.9 4.6 1.4 4.2 5.6 2.9 2.0 1.5 3.3 4.1 3.8 3.5 2.5 4.3 3.8 2.4 3.3 3.3 3.2 2.6 8.3 2.4 4.8 2.9 3.8 3.9 3.2 3.1 3.6 2.4 5.0 2.9 4.8 2.6 3.3 1.8 2.9 9.6 6.4 4.7 2.9 7.7 2.4 5.3 7.1 2.4 3.4 2.1 3.2 4.4 2.4 4.7 4.5 1.4 5.2 7.0 2.5 2.6 5.5 2.1 2.3 7.5 4.4 2.8 4.1 4.5 8.0 5.5 3.8 5.0 4.1 2.1 5.0 2.7 6.3 5.9 3.0 2.3 3.1 2.1 3.1 3.4 5.1 3.7 3.4 4.1 4.0 4.3 0.1 0.8 0.0 1.0 1.5 1.6 0.8 1.4 1.1 1.7 1.0 1.3 1.1 0.4 1.8 1.1 1.6 1.7 1.3 3.3 3.5 2.7 4.0 3.3 3.6 3.3 2.5 2.6 1.5 3.5 3.2 1.8 9.6 5.9 5.2 3.8 2.2 4.0 4.0 4.0 3.8 6.2 4.7 11.6 2.8 2.9 3.7 2.1 15.1 2.3 2.5 5.9 7.0 2.9 3.3 4.9 3.2 5.4 9.4 8.3 3.5 12.3 4.3 4.1 3.4 5.7 6.5 3.6 11.4 7.1 8.4 7.9 4.3 2.0 3.2 2.5 2.5 2.5 3.4 5.4 3.7 5.3 2.6 4.1 4.0 4.7 3.7 1.7 1.9 8.8 4.9 1.6 8.6 5.3 3.9 0.0 2.7 3.4 5.8 9.8 6.5 3.0 11.4 3.3 12.6 6.2 3.2 EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109565996 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" 23.3 28.4 18.6 17.6 19.9 16.9 32.4 23.4 26.3 36.1 19.8 28.6 23.5 22.8 44.7 17.0 27.6 19.4 24.7 19.1 20.5 37.0 45.2 28.1 25.4 18.9 19.0 22.2 36.7 34.9 20.5 18.1 19.0 23.3 31.2 32.5 42.9 27.6 53.2 17.9 21.0 17.0 19.1 20.7 27.2 25.3 19.3 20.6 57.4 42.3 27.0 17.2 15.3 20.2 36.7 25.2 25.3 17.3 15.3 24.9 19.7 19.5 14.6 27.0 25.4 25.7 38.1 51.7 33.0 13.8 21.8 25.2 24.4 31.3 28.5 57.6 26.9 56.9 15.8 39.6 34.3 20.0 16.1 19.9 60.1 23.4 47.2 21.9 25.7 45.8 59.8 37.0 24.0 55.8 58.2 31.5 15.8 70.1 25.2 30.9 20.1 43.7 31.4 23.7 27.6 22.1 21.3 22.6 27.6 18.4 44.7 25.6 17.5 20.9 15.0 19.1 14.4 54.9 38.3 48.7 21.2 52.7 19.6 5.8 13.4 14.7 19.3 19.5 34.1 40.7 27.1 27.0 22.5 40.3 33.5 30.4 2.8 29.4 17.3 23.8 33.4 14.7 18.6 19.9 23.4 26.3 19.1 20.5 18.9 19.0 19.0 19.1 19.3 20.2 32.0 121.8 102.4 12.7 40.2 21.7 28.6 51.8 44.9 34.5 36.8 46.0 37.6 54.3 65.1 29.5 6.2 50.2 24.0 33.6 64.6 47.3 134.7 42.9 26.7 34.5 31.8 36.0 16.1 65.8 34.0 28.8 22.4 33.0 46.9 16.0 23.2 48.8 32.7 50.5 16.1 39.4 50.8 24.7 22.1 115.0 29.2 27.9 19.6 11.2 25.3 53.4 27.8 18.1 16.1 38.5 41.3 23.0 53.8 36.8 50.5 58.5 61.8 34.7 32.9 35.1 32.1 101.6 50.4 40.5 19.9 22.2 28.5 34.7 46.0 31.7 EBI3 "IL27B, IL35B" ENSG00000105246 "Epstein-Barr virus induced 3" Q14213 19 4229523-4237528 "Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "placenta: 147.6" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 485.6;monocytes: 505.7;Syncytiotrophoblasts: 336.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "intermediate monocyte: 4.8;memory B-cell: 18.7;naive B-cell: 14.7;non-classical monocyte: 6.3" "Group enriched" "Detected in many" 14 "B-cells: 18.7;monocytes: 6.3" "Cell line enriched" "Detected in some" 13 "HDLM-2: 218.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046635 Enhanced "Secreted to blood" NA NA 203000 1400000 "Cluster 19: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 44: HDLM-2 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA046635: AB_2679729" "unprognostic (7.26e-2)" "unprognostic (1.49e-2)" "unprognostic (9.44e-2)" "unprognostic (1.31e-1)" "unprognostic (2.59e-1)" "unprognostic (2.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.10e-2)" "unprognostic (7.78e-2)" "unprognostic (4.87e-2)" "unprognostic (4.25e-3)" "unprognostic (8.27e-2)" "prognostic unfavorable (1.04e-8)" "unprognostic (1.97e-1)" "unprognostic (2.78e-2)" "unprognostic (9.29e-2)" "unprognostic (4.67e-2)" 4.7 4.7 3.8 14.6 3.3 1.2 1.7 3.4 5.3 1.5 3.2 3.0 4.3 1.1 0.1 1.0 2.4 5.4 1.4 3.8 3.7 2.1 3.3 2.9 20.2 5.7 4.2 1.3 2.5 0.4 1.7 147.6 5.2 1.8 1.6 0.1 1.8 1.4 0.2 0.6 8.4 2.1 4.5 34.0 3.7 0.9 5.8 9.4 0.9 0.4 7.3 4.8 1.0 6.1 0.1 1.7 0.1 0.0 0.0 0.0 7.3 0.7 4.2 0.4 0.2 1.3 1.2 4.2 16.4 0.0 2.0 0.1 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.2 0.3 0.0 7.7 0.4 0.0 2.1 0.6 1.6 0.1 0.0 0.4 0.5 0.1 0.1 0.0 3.0 0.4 0.0 0.0 0.0 0.6 0.3 2.6 0.0 0.2 0.4 0.0 0.0 0.0 2.7 0.2 0.2 0.9 0.3 5.1 0.0 0.2 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.1 0.0 0.0 4.8 0.0 18.7 0.0 0.0 0.8 14.7 0.0 0.0 0.2 0.0 6.3 0.0 0.0 0.6 3.8 3.3 3.4 5.3 3.8 3.7 5.7 4.2 5.2 4.5 5.8 6.1 0.5 0.0 0.5 0.3 8.4 0.4 0.0 13.3 0.0 0.0 0.2 0.6 0.1 1.5 10.7 0.0 0.0 10.6 0.5 0.0 0.0 2.8 0.0 0.3 0.4 1.3 0.0 0.0 0.6 0.9 485.6 0.7 0.0 0.3 11.4 0.0 1.1 0.1 9.6 0.0 0.4 0.0 6.1 102.6 11.3 0.0 0.0 19.0 0.0 5.6 505.7 0.1 0.0 0.0 0.1 0.6 0.0 0.0 2.6 0.1 0.0 0.6 1.5 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 336.4 1.0 0.1 0.0 0.1 ECHS1 SCEH ENSG00000127884 "Enoyl-CoA hydratase, short chain 1" P30084 10 133362485-133373354 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1128.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 1476.3;Proximal tubular cells: 2336.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003783, HPA021995, HPA022476" Enhanced Enhanced Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "CAB003783: , HPA021995: AB_1847974, HPA022476: AB_1847975" "unprognostic (3.68e-1)" "unprognostic (2.46e-3)" "unprognostic (9.57e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-1)" "unprognostic (3.14e-1)" "unprognostic (2.51e-3)" "unprognostic (2.30e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "prognostic favorable (8.57e-5)" "unprognostic (2.84e-2)" "unprognostic (1.19e-2)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" 302.4 127.1 127.7 53.7 127.8 43.9 116.9 131.3 136.1 59.8 149.7 143.1 171.6 47.0 89.3 107.9 90.5 66.7 226.4 133.1 129.9 481.7 1128.7 48.5 52.4 129.4 129.9 71.3 96.8 98.7 74.3 73.6 128.8 102.0 104.6 39.8 163.4 123.2 294.3 68.2 153.6 59.4 130.3 48.4 84.5 52.6 134.6 40.0 88.5 271.6 59.0 87.4 57.8 136.0 185.1 229.2 120.4 303.4 173.0 111.4 110.5 132.2 175.9 183.2 154.1 509.5 174.0 139.2 111.9 151.4 94.4 167.7 160.2 136.1 132.0 107.4 281.2 138.5 128.1 367.2 145.0 180.4 93.5 124.5 115.9 121.2 153.6 160.8 165.1 98.3 127.8 117.4 181.6 443.9 90.7 352.0 84.4 289.8 272.1 152.8 146.4 74.6 227.8 236.0 78.1 123.4 137.0 224.1 178.9 69.4 174.8 171.5 132.1 81.3 115.9 169.9 177.4 87.0 58.8 159.8 192.4 98.8 68.7 96.1 184.7 86.8 105.5 212.2 137.6 178.7 117.8 115.8 242.6 148.9 119.3 115.8 19.8 166.0 168.1 104.9 123.0 233.0 127.7 127.8 131.3 136.1 133.1 129.9 129.4 129.9 128.8 130.3 134.6 136.0 99.2 44.8 82.7 16.3 60.5 68.2 86.9 271.8 62.6 57.0 98.5 119.6 255.2 210.1 161.5 174.7 6.2 470.2 34.0 298.6 565.4 162.8 29.9 148.9 92.7 71.4 131.7 72.2 11.6 101.1 163.5 92.5 87.7 226.4 91.2 120.0 88.5 1476.3 221.1 45.4 11.0 223.0 175.0 92.1 61.5 39.1 77.6 88.0 135.2 10.3 113.0 145.2 45.3 10.6 24.3 107.8 248.6 91.7 57.5 88.0 486.2 2336.5 93.2 55.2 85.5 57.0 98.8 52.9 66.1 125.2 76.3 299.1 62.5 220.0 317.2 127.8 ECM2 ENSG00000106823 "Extracellular matrix protein 2" O94769 9 92493554-92536655 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 122.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 73.3;Hepatocytes: 49.3;Leydig cells: 122.1;Peritubular cells: 69.6;Skeletal myocytes: 43.6;Smooth muscle cells: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "ASC diff: 19.1;ASC TERT1: 34.5;HSkMC: 36.8;hTCEpi: 42.8;hTERT-HME1: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035347, HPA035348" Approved Approved "Mitotic spindle,Centrosome,Cytosol" "Secreted to extracellular matrix" Yes NA 10000000 "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Centrosome, Cytosol" "Mitotic spindle" "HPA035347: AB_10669856, HPA035348: " "unprognostic (2.48e-1)" "unprognostic (2.11e-1)" "unprognostic (2.27e-2)" "unprognostic (2.20e-2)" "unprognostic (5.35e-2)" "unprognostic (2.30e-1)" "prognostic favorable (4.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.12e-3)" "unprognostic (2.39e-2)" "unprognostic (3.80e-2)" "unprognostic (6.63e-3)" 122.1 14.3 5.0 2.1 5.0 0.6 34.8 6.0 4.9 43.5 8.1 6.8 9.0 40.8 23.2 9.0 30.0 31.7 31.5 4.5 11.6 28.4 81.5 22.5 8.3 5.2 10.3 91.6 6.3 9.1 6.1 3.5 5.8 21.2 7.4 0.3 7.2 22.2 7.4 9.7 14.8 27.8 4.4 0.9 4.3 16.8 8.0 5.0 11.4 24.6 7.8 13.3 11.1 12.0 0.7 0.1 0.4 0.0 19.1 34.5 1.3 0.8 1.1 0.1 0.5 0.6 0.0 0.0 0.1 1.9 0.3 0.5 0.9 0.8 0.1 4.4 0.0 0.0 0.0 0.0 3.3 0.2 0.0 36.8 42.8 0.9 11.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.1 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.0 6.0 4.9 4.5 11.6 5.2 10.3 5.8 4.4 8.0 12.0 12.9 0.0 2.3 5.5 0.3 11.5 0.1 0.6 0.6 3.0 0.3 1.3 5.5 1.5 2.0 0.0 2.1 0.1 0.3 0.2 0.0 0.1 5.1 0.6 18.6 5.2 0.0 0.8 3.4 0.0 16.2 73.3 0.5 0.5 0.0 18.2 2.2 49.3 0.4 0.0 2.8 0.4 0.0 1.3 15.4 8.9 122.1 1.1 5.4 17.8 0.1 0.1 0.0 0.5 2.9 0.0 0.2 69.6 1.4 0.1 11.1 9.2 3.3 2.5 26.3 43.6 50.2 0.9 0.6 0.9 9.1 0.8 0.9 13.5 0.6 0.2 EDARADD ENSG00000186197 "EDAR associated death domain" Q8WWZ3 1 236348257-236502915 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 8.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.7;granulocytes: 22.7;Syncytiotrophoblasts: 22.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 8 "basophil: 49.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 49.5" "Cell line enhanced" "Detected in some" "BEWO: 15.9;HDLM-2: 13.2;HMC-1: 52.7;RT4: 45.3;T-47d: 12.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA018836 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA018836: AB_1847984" "unprognostic (3.74e-1)" "unprognostic (3.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.12e-2)" "unprognostic (2.06e-3)" "unprognostic (3.12e-3)" "unprognostic (9.94e-2)" "unprognostic (2.96e-2)" "unprognostic (2.62e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-2)" "unprognostic (5.72e-2)" "unprognostic (3.00e-1)" "unprognostic (2.47e-1)" "unprognostic (1.90e-2)" "unprognostic (9.62e-3)" 0.4 0.1 0.2 0.4 0.1 0.4 4.8 0.1 0.1 0.7 0.0 0.3 0.4 0.4 5.2 3.3 1.2 0.8 0.9 0.1 0.1 1.1 0.3 0.7 1.2 0.2 0.2 0.4 3.8 0.1 0.1 4.9 0.1 3.6 0.3 0.0 1.4 6.1 0.0 5.8 0.3 0.1 0.1 1.2 6.3 3.4 0.2 2.3 6.4 0.0 2.6 8.7 1.0 0.1 0.0 3.8 0.3 0.0 0.0 0.0 15.9 0.0 0.0 1.3 0.8 1.0 0.0 0.0 0.0 0.2 4.3 8.8 6.5 9.6 1.2 13.2 7.6 0.1 0.1 1.4 0.0 0.4 52.7 0.0 2.7 0.9 0.8 0.0 0.0 1.8 0.4 0.0 0.0 0.4 0.3 0.0 3.9 0.0 0.0 3.4 0.1 0.0 0.0 45.3 0.4 0.3 0.0 1.2 0.2 0.3 12.6 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 49.5 0.3 0.1 3.1 0.4 4.1 0.1 4.7 6.1 0.5 0.2 0.4 3.2 0.3 5.3 0.2 0.1 5.1 2.1 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.0 1.3 0.0 0.4 6.9 7.3 16.3 13.1 0.0 7.1 7.4 4.1 5.7 8.4 0.0 0.0 26.7 3.0 0.1 3.9 1.7 10.6 0.2 1.2 1.2 0.0 2.5 0.5 0.9 14.2 1.1 5.1 0.4 22.7 2.8 5.0 0.5 3.4 0.0 0.6 0.1 8.2 1.5 8.9 9.3 0.3 0.6 12.4 1.0 3.7 0.6 0.0 1.0 0.4 0.6 0.0 0.4 1.8 4.2 0.1 0.4 3.2 0.1 0.0 1.4 6.1 13.4 3.7 6.5 5.3 22.6 6.2 0.3 0.0 5.3 EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 121.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 358.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA022859: AB_1848029, HPA023092: AB_2293240, HPA023402: AB_1848031" "unprognostic (4.79e-2)" "unprognostic (6.54e-2)" "unprognostic (6.42e-2)" "unprognostic (4.37e-3)" "unprognostic (2.77e-1)" "unprognostic (3.44e-2)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-2)" "unprognostic (5.89e-3)" "unprognostic (5.22e-2)" "unprognostic (3.46e-1)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-3)" 21.7 20.8 22.7 20.8 28.6 14.5 20.0 36.4 35.7 28.3 13.2 21.2 23.2 23.4 38.0 27.5 24.2 21.8 33.9 29.5 9.3 29.8 44.5 27.8 25.3 52.7 13.6 19.3 18.6 33.6 12.0 20.4 59.0 26.9 18.4 121.6 17.3 29.3 41.6 21.2 23.5 36.1 7.0 23.5 22.8 22.1 16.1 24.3 37.8 49.1 27.9 26.9 14.0 23.9 55.3 49.0 15.0 12.4 59.9 68.8 29.9 38.6 54.0 31.5 41.3 10.8 40.4 33.8 35.5 87.6 41.8 17.9 23.9 52.9 38.3 78.3 13.1 33.7 22.7 22.0 57.5 13.0 34.1 58.6 29.6 31.2 49.0 52.2 40.2 16.4 18.7 44.3 56.5 36.1 36.5 11.9 8.5 47.3 30.4 14.5 29.4 16.1 38.0 34.1 10.0 34.6 76.9 10.8 30.6 39.3 34.4 22.0 56.3 55.6 50.9 27.4 40.9 31.3 28.8 20.9 41.2 31.0 29.0 12.0 16.8 17.4 16.2 23.3 14.5 12.6 13.0 13.3 17.3 11.2 11.6 12.0 10.1 15.5 40.9 4.0 11.3 15.8 22.7 28.6 36.4 35.7 29.5 9.3 52.7 13.6 59.0 7.0 16.1 23.9 32.6 41.7 42.8 90.8 40.7 21.2 25.3 29.5 25.0 358.8 29.9 16.6 57.4 28.6 37.5 51.5 91.8 22.8 34.1 33.5 21.5 28.7 4.5 25.9 35.1 29.1 11.4 13.3 126.8 30.9 22.2 34.4 29.0 20.7 25.9 19.8 25.0 79.9 44.5 26.9 122.6 18.7 26.4 59.4 25.0 8.0 19.9 52.9 8.8 60.0 53.3 42.3 42.2 77.9 55.6 25.5 36.0 44.4 32.6 55.8 39.9 58.4 27.7 107.5 19.7 32.3 41.4 52.9 30.9 39.1 31.4 37.1 37.3 36.8 17.0 36.7 EGF ENSG00000138798 "Epidermal growth factor" P01133 4 109912883-110013766 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 110.2;pancreas: 89.5;skeletal muscle: 29.6" "Cell type enhanced" "Detected in some" "Breast glandular cells: 12.9;Breast myoepithelial cells: 8.1;Cardiomyocytes: 8.2;Distal tubular cells: 7.9;Excitatory neurons: 8.5;Inhibitory neurons: 11.2;Muller glia cells: 26.2;Skeletal myocytes: 8.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.4;SK-BR-3: 11.6;U-251 MG: 3.6" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA 209000 680000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.83e-2)" "unprognostic (1.02e-2)" "unprognostic (8.50e-3)" "unprognostic (1.88e-3)" "unprognostic (4.24e-2)" "unprognostic (1.64e-3)" "unprognostic (5.06e-4)" "unprognostic (8.30e-2)" "unprognostic (2.21e-3)" "unprognostic (4.25e-2)" "unprognostic (1.80e-2)" "unprognostic (2.95e-1)" "unprognostic (7.72e-3)" "unprognostic (4.64e-5)" "unprognostic (2.63e-1)" "unprognostic (9.80e-5)" "unprognostic (3.92e-3)" 0.0 0.0 1.0 0.1 1.0 0.2 14.7 0.2 0.8 0.0 0.2 0.8 0.0 0.4 2.4 0.7 0.3 1.0 2.8 0.9 2.0 110.2 0.0 0.5 0.0 1.4 0.9 0.0 89.5 0.2 0.4 0.0 1.5 1.4 1.1 13.6 15.7 0.4 29.6 0.7 0.2 0.5 1.2 0.1 0.0 0.1 0.7 0.0 3.0 17.4 0.0 0.4 0.1 1.8 0.2 0.2 1.9 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.4 0.1 0.0 0.0 6.4 0.6 1.6 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.6 1.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.6 0.1 0.0 0.0 2.3 0.0 0.4 0.1 0.1 0.5 0.4 0.2 0.0 0.0 0.0 11.6 0.4 1.2 2.8 0.0 0.0 0.9 1.3 0.0 3.6 0.0 0.0 0.0 1.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 1.0 1.0 0.2 0.8 0.9 2.0 1.4 0.9 1.5 1.2 0.7 1.8 0.1 0.0 0.0 3.3 0.0 1.0 0.2 0.1 0.0 1.0 12.9 8.1 8.2 0.0 0.5 0.0 0.0 0.0 0.2 2.0 7.9 0.2 5.6 0.2 0.1 0.6 0.0 0.0 8.5 5.7 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 11.2 0.1 0.0 0.0 0.0 1.5 0.0 1.0 0.0 0.0 0.3 26.2 0.0 1.5 0.3 1.0 0.4 0.0 0.0 1.1 0.1 1.2 1.0 1.2 0.0 8.2 0.2 0.5 0.4 0.0 1.4 0.0 0.1 0.1 1.6 0.3 EHHADH ECHD ENSG00000113790 "Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase" Q08426 3 185190624-185281990 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Multifunctional enzyme, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 11 "kidney: 144.3;liver: 344.5" "Group enriched" "Detected in many" 10 "Hepatocytes: 289.0;Proximal tubular cells: 147.1" "Group enriched" "Detected in all" 7 "liver cancer: 42.2;renal cancer: 25.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036401, HPA042021" Enhanced NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036401: AB_10670165, HPA042021: AB_2677801" "unprognostic (1.20e-1)" "unprognostic (5.99e-2)" "unprognostic (2.17e-3)" "unprognostic (2.69e-2)" "unprognostic (6.82e-2)" "unprognostic (1.48e-1)" "unprognostic (4.79e-3)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (3.89e-2)" "unprognostic (3.19e-3)" "unprognostic (1.87e-1)" "prognostic favorable (1.28e-5)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.96e-2)" "unprognostic (2.80e-1)" 10.8 4.3 2.1 3.0 2.9 1.2 4.1 3.9 2.7 3.5 9.2 14.2 21.5 2.8 3.5 5.5 3.6 4.4 10.7 2.1 3.1 144.3 344.5 4.3 2.1 3.2 4.1 2.6 9.9 7.8 1.5 3.2 3.0 6.3 10.8 1.6 5.7 2.2 1.7 4.5 12.9 3.7 2.5 3.7 10.4 2.7 3.1 2.1 6.5 5.6 2.8 3.6 2.1 2.8 12.3 5.0 1.4 0.0 7.3 6.1 1.5 5.7 1.8 3.7 4.1 21.9 7.5 0.0 22.1 5.7 1.4 5.8 0.0 4.8 7.6 16.2 5.2 8.6 1.3 22.5 4.7 1.0 0.2 8.7 6.0 3.7 3.4 5.0 5.5 0.0 5.7 6.1 7.2 6.4 0.2 5.1 3.0 4.3 6.3 0.0 9.9 0.5 15.4 6.8 4.4 6.4 11.2 6.4 10.5 12.1 23.7 10.1 2.6 2.4 3.6 1.9 0.5 1.7 5.6 0.5 0.8 3.9 4.0 0.1 0.9 0.0 0.6 0.8 0.4 0.5 0.4 0.9 2.4 0.0 0.6 1.0 0.0 1.2 0.8 1.0 0.6 0.4 2.1 2.9 3.9 2.7 2.1 3.1 3.2 4.1 3.0 2.5 3.1 2.8 4.9 16.0 10.9 20.9 4.5 1.5 1.4 1.9 1.2 0.7 3.2 2.3 19.2 17.2 3.9 20.2 4.2 8.9 0.4 17.8 19.6 2.1 0.2 6.5 5.1 3.9 7.7 9.7 4.9 6.8 2.9 1.6 8.6 3.1 0.0 6.1 13.6 289.0 4.4 0.0 5.7 12.8 0.0 10.5 1.0 0.7 0.6 2.7 3.6 4.7 9.4 1.9 0.0 3.5 8.0 3.7 9.3 0.4 0.8 2.5 15.0 147.1 4.0 1.2 0.0 1.1 2.4 3.7 4.2 4.9 0.4 1.4 2.2 3.6 10.8 1.8 EIF2AK1 "HRI, KIAA1369" ENSG00000086232 "Eukaryotic translation initiation factor 2 alpha kinase 1" Q9BQI3 7 6022247-6059175 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Protein synthesis inhibitor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Cytotrophoblasts: 219.1;Erythroid cells: 422.0;Syncytiotrophoblasts: 371.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016496, CAB022082, HPA061675" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "CAB022082: , HPA016496: AB_1848057, HPA061675: AB_2684583" "unprognostic (7.15e-3)" "unprognostic (2.00e-2)" "unprognostic (1.45e-1)" "unprognostic (2.91e-1)" "unprognostic (6.70e-2)" "unprognostic (9.69e-3)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.36e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-2)" 27.2 39.4 28.1 27.7 28.9 105.9 35.9 30.6 36.1 29.0 34.9 48.8 37.1 25.0 37.4 30.4 31.0 23.8 33.8 28.1 30.6 43.8 65.1 30.3 35.2 30.5 28.9 29.3 44.3 78.0 25.9 52.3 31.6 35.0 47.3 29.0 46.8 24.2 38.3 33.3 37.2 23.8 29.1 26.6 49.1 19.5 29.8 43.6 39.3 34.4 40.4 27.2 22.4 33.7 144.5 90.5 71.2 108.8 66.4 59.6 92.4 73.0 66.8 64.2 80.8 83.7 96.2 112.5 77.4 81.3 115.5 100.4 93.1 67.1 82.2 69.8 140.3 115.9 91.6 127.3 54.3 100.8 102.0 48.1 82.8 60.7 64.9 67.7 69.4 88.1 189.0 106.8 61.4 146.5 55.6 128.6 88.5 84.6 99.7 120.0 74.6 134.0 82.3 70.3 87.3 156.5 139.3 186.6 63.8 98.6 141.0 122.4 65.9 37.0 134.2 65.3 78.2 106.5 114.8 115.6 73.9 129.8 108.7 11.1 6.9 17.3 8.2 5.5 5.6 12.3 6.5 9.3 6.9 9.5 7.5 6.6 3.7 10.2 6.2 6.0 8.9 4.8 28.1 28.9 30.6 36.1 28.1 30.6 30.5 28.9 31.6 29.1 29.8 33.7 23.1 38.5 43.7 14.4 42.8 23.8 34.9 34.3 41.5 29.7 52.5 34.9 49.6 45.8 37.7 44.1 16.7 219.1 52.5 57.1 66.5 55.0 8.8 59.5 42.3 27.5 38.5 422.0 21.8 44.8 82.1 29.7 64.7 48.1 20.8 44.9 21.0 63.2 53.8 32.0 21.9 68.7 54.9 39.0 29.9 16.1 34.5 65.2 24.9 13.1 62.8 46.4 70.0 19.1 26.9 53.0 47.0 37.6 60.1 43.3 47.5 66.1 48.3 26.5 13.1 32.0 26.0 33.7 34.5 45.5 22.4 371.0 38.0 57.1 52.7 32.3 EIF2B2 "EIF-2Bbeta, EIF2B" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 12000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: AB_1840834, HPA005841: AB_1078725, HPA048028: AB_2680235" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (6.71e-2)" "unprognostic (7.64e-2)" "unprognostic (3.45e-3)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "prognostic favorable (2.95e-4)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" 2.7 5.3 4.0 2.9 4.5 3.2 3.6 8.7 4.8 3.9 2.2 3.0 3.0 3.6 4.9 3.8 3.1 4.0 3.9 3.6 6.1 4.9 3.3 2.7 4.0 4.5 4.2 2.9 4.0 8.5 3.5 4.8 4.5 4.1 3.8 6.8 2.8 4.5 5.5 4.0 2.8 3.4 2.9 2.7 2.6 3.9 4.8 3.9 11.5 7.1 4.2 4.0 2.6 6.9 5.9 7.0 5.6 6.4 6.3 5.2 7.4 3.7 6.1 7.1 8.2 9.0 5.9 5.2 2.3 5.8 4.5 4.4 8.8 8.7 10.6 3.2 6.5 4.6 6.3 6.2 8.2 3.4 5.3 4.8 8.2 9.1 9.3 6.1 24.8 4.5 4.2 4.9 15.5 17.4 5.5 4.3 4.0 7.3 10.3 3.4 6.6 4.3 10.1 7.0 6.0 4.8 3.9 5.5 8.4 6.9 9.0 3.2 6.4 5.4 5.2 2.4 4.8 8.4 7.5 6.2 5.9 4.3 4.2 4.2 1.8 1.4 3.0 1.9 2.5 2.1 2.6 2.5 2.4 2.0 1.9 2.0 1.0 3.3 1.8 2.0 4.0 2.5 4.0 4.5 8.7 4.8 3.6 6.1 4.5 4.2 4.5 2.9 4.8 6.9 18.9 19.2 11.5 6.2 14.1 17.7 19.5 28.9 18.2 28.2 15.4 17.0 18.2 22.8 21.5 25.8 45.9 51.5 16.1 15.3 41.1 36.2 12.1 17.0 14.5 32.1 15.6 20.8 5.3 33.1 56.5 18.3 12.8 12.8 21.5 17.5 13.2 11.9 33.7 28.6 5.4 9.0 20.3 19.1 11.9 12.7 15.8 18.8 14.2 1.9 28.0 27.3 28.8 2.5 8.5 28.1 11.7 16.1 11.3 17.5 19.0 50.8 17.2 29.4 26.3 16.9 27.9 84.2 27.4 27.3 21.9 165.5 14.9 30.5 19.7 19.2 EIF4E "EIF4E1, EIF4EL1, EIF4F" ENSG00000151247 "Eukaryotic translation initiation factor 4E" P06730 4 98879276-98929133 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Translation regulation" "Initiation factor, RNA-binding" "Autism, Autism spectrum disorder, Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 927.0;Late spermatids: 2284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004077, CAB016316, HPA068358" Supported Supported "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA 450000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytosol, Cytoplasmic bodies" Nucleoplasm "CAB004077: AB_823488, CAB016316: AB_627502, HPA068358: " "unprognostic (3.07e-3)" "unprognostic (1.43e-1)" "unprognostic (6.53e-3)" "unprognostic (7.52e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-3)" "unprognostic (2.03e-5)" "unprognostic (6.55e-3)" "unprognostic (1.09e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (1.10e-3)" "unprognostic (5.40e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" 38.0 37.4 27.4 37.7 28.5 57.4 35.6 32.5 34.6 28.5 20.9 45.1 35.9 30.5 38.0 51.7 31.7 31.3 37.5 27.8 34.3 47.4 43.3 27.0 44.6 29.2 31.1 29.1 27.0 45.1 17.0 35.9 29.2 31.4 52.2 54.0 31.2 30.7 39.2 24.2 34.4 39.4 36.2 31.5 35.8 62.6 31.4 53.2 52.6 48.1 58.0 54.4 29.8 34.3 101.1 85.2 139.8 96.5 73.4 74.2 87.3 184.6 105.3 137.0 100.5 111.0 122.7 194.7 59.4 104.4 94.3 49.0 181.9 124.9 158.9 133.5 56.2 135.6 52.7 105.8 62.6 199.3 104.8 54.5 78.3 104.8 82.9 81.5 108.3 97.6 226.6 95.2 120.0 82.9 189.2 110.6 115.0 189.2 72.2 119.7 94.4 90.0 122.0 85.3 123.3 80.3 85.5 188.4 65.4 93.3 89.9 85.9 86.5 110.0 121.6 96.9 153.7 71.4 185.4 179.4 99.7 102.7 127.1 39.5 34.7 59.3 38.2 42.1 44.4 50.0 43.2 40.2 39.6 43.6 47.3 47.3 26.3 54.3 54.8 33.5 46.5 50.3 27.4 28.5 32.5 34.6 27.8 34.3 29.2 31.1 29.2 36.2 31.4 34.3 45.2 32.1 42.2 29.7 93.1 362.1 227.5 202.2 149.7 87.9 81.6 41.1 27.5 55.8 106.0 60.7 35.5 105.3 56.2 140.5 256.3 88.9 927.0 76.1 84.0 77.8 64.6 192.8 45.2 67.4 150.0 87.1 80.0 119.0 51.4 28.0 40.0 77.1 121.1 85.8 45.0 77.4 227.9 61.9 327.6 2284.9 50.7 122.1 193.9 25.3 69.8 82.0 57.7 35.2 50.9 83.8 107.1 49.2 113.0 191.1 83.2 189.2 76.8 64.7 52.6 78.7 151.7 98.7 87.1 171.2 370.9 119.0 82.2 39.8 97.3 224.3 EMC4 "FLJ90746, MGC24415, PIG17, TMEM85" ENSG00000128463 "ER membrane protein complex subunit 4" Q5J8M3 15 34225013-34230156 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053440 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA053440: AB_2682151" "unprognostic (8.99e-2)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (3.29e-2)" "unprognostic (9.23e-2)" "unprognostic (1.29e-3)" "unprognostic (3.25e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (1.78e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-2)" "unprognostic (2.52e-1)" "unprognostic (5.42e-2)" "unprognostic (4.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.97e-2)" 76.1 68.1 83.8 48.8 86.5 58.7 68.4 90.3 103.7 69.3 92.0 69.1 55.1 67.0 102.9 78.3 67.8 52.3 86.4 87.6 88.8 67.9 91.3 57.3 55.4 87.2 85.2 66.2 90.7 83.0 60.3 59.2 88.4 62.3 58.2 65.4 79.0 63.7 214.4 63.9 57.1 58.8 86.9 49.1 69.8 49.4 85.7 58.1 60.6 136.7 54.2 59.2 71.4 95.2 123.1 248.2 103.9 135.1 133.2 119.6 95.0 137.7 156.9 166.0 143.4 162.0 106.1 48.5 177.7 160.0 145.6 229.4 107.0 135.3 118.7 148.3 103.7 91.9 219.4 154.8 161.0 139.8 87.8 121.4 126.3 121.4 136.0 118.1 139.8 144.6 117.0 186.6 147.1 137.9 109.9 149.9 116.9 165.0 163.5 102.0 94.7 138.3 161.0 186.9 137.1 166.4 101.7 148.3 77.6 74.8 99.3 164.7 106.5 151.3 103.8 131.8 142.7 162.8 251.5 122.0 184.5 164.1 131.1 256.5 158.6 176.9 154.5 173.9 170.0 237.2 170.6 185.8 162.6 187.7 172.2 168.8 88.5 197.8 200.2 166.6 216.1 277.6 83.8 86.5 90.3 103.7 87.6 88.8 87.2 85.2 88.4 86.9 85.7 95.2 75.3 54.5 67.7 8.8 67.9 91.5 103.7 206.5 55.8 35.8 83.7 104.1 58.7 58.6 132.4 66.2 18.8 150.6 62.5 39.5 125.2 180.3 121.8 67.6 55.1 86.1 52.0 38.7 14.1 172.3 173.6 87.8 36.7 69.1 88.0 63.2 64.2 78.6 113.7 18.5 15.4 62.8 166.8 48.5 73.2 27.4 100.6 56.5 101.4 13.1 87.9 98.4 76.2 15.1 16.9 184.0 65.4 90.7 117.9 89.6 71.8 117.5 133.3 42.8 85.5 81.4 123.2 169.7 91.9 60.2 110.0 141.7 68.8 69.7 66.4 125.4 EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 153.1;Syncytiotrophoblasts: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved Approved Vesicles NA NA 180000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA012757: AB_1848145" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.81e-3)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-3)" "unprognostic (3.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (7.48e-2)" "unprognostic (7.03e-2)" 11.2 32.7 23.2 13.6 41.7 14.1 12.9 43.2 37.6 16.4 9.7 21.3 11.5 9.1 6.8 40.2 12.0 10.9 20.4 19.5 36.1 17.5 7.9 13.6 13.4 57.6 35.4 5.2 21.1 55.1 14.3 19.8 52.8 15.8 14.4 49.0 29.0 18.3 5.7 38.6 11.9 7.1 27.9 12.9 18.9 3.5 40.3 16.5 20.9 4.9 12.5 19.5 24.9 57.9 47.6 16.2 3.2 1.1 25.0 13.6 17.4 29.2 37.0 12.6 14.8 6.2 39.5 14.6 17.0 15.4 4.0 39.7 6.0 57.4 4.0 56.7 15.0 5.7 19.5 12.4 47.1 18.5 13.4 21.1 74.5 15.1 74.1 10.5 9.4 28.0 18.3 38.5 10.0 49.9 10.3 4.2 1.9 75.7 14.3 2.3 5.6 18.9 33.3 61.2 17.8 3.3 16.4 32.0 22.1 17.0 18.7 18.9 15.1 0.0 5.4 4.8 0.3 66.2 43.9 7.9 20.4 20.9 38.7 7.8 3.7 5.7 6.5 4.8 5.1 5.5 4.4 6.7 4.4 2.2 2.9 3.9 1.0 2.6 5.2 6.4 5.8 3.9 23.2 41.7 43.2 37.6 19.5 36.1 57.6 35.4 52.8 27.9 40.3 57.9 10.6 3.2 13.1 8.5 15.7 18.6 42.9 40.3 27.3 32.2 13.2 14.2 9.0 14.3 25.5 35.0 14.6 66.4 24.5 34.1 37.2 16.8 72.1 28.6 9.0 13.8 17.5 5.5 29.7 20.8 20.4 7.6 38.7 20.1 19.1 6.7 20.3 6.4 15.8 28.6 46.0 32.6 26.4 8.8 9.6 27.0 4.1 8.7 19.6 5.6 13.1 16.4 12.3 15.1 68.0 17.9 29.1 7.2 25.0 23.7 11.0 7.5 40.7 153.1 0.0 6.8 16.4 3.5 6.1 29.6 14.3 101.0 23.2 39.1 31.9 41.9 ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 243.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 100.1;Respiratory ciliated cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Cell line enhanced" "Detected in some" "CAPAN-2: 11.1;HSkMC: 7.1;SuSa: 6.2;T-47d: 8.7;U-266/84: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 620000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol Nucleoplasm "HPA016902: AB_1848172" "unprognostic (1.12e-1)" "unprognostic (5.19e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-1)" "unprognostic (7.61e-2)" "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "prognostic favorable (4.57e-4)" "unprognostic (1.96e-1)" "unprognostic (9.89e-2)" "prognostic favorable (4.04e-4)" "unprognostic (7.00e-2)" "prognostic favorable (4.44e-13)" "unprognostic (4.40e-2)" "unprognostic (2.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.60e-1)" 1.8 8.6 6.2 1.1 7.6 0.2 13.4 6.9 12.6 12.8 4.0 2.6 1.5 1.8 243.6 1.8 15.4 7.0 4.4 7.0 9.7 24.3 0.5 8.8 1.2 5.8 13.0 9.7 9.7 46.3 19.8 1.7 6.2 29.4 3.2 30.6 14.4 31.0 10.7 1.6 1.9 0.9 4.5 5.7 6.7 35.5 14.0 8.2 51.0 10.3 1.4 5.6 1.8 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.5 0.1 0.3 11.1 1.8 3.6 0.2 3.7 0.0 0.6 1.5 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.4 1.9 0.0 0.5 2.3 5.4 0.0 0.0 0.2 0.2 4.5 0.6 4.7 0.2 0.0 4.6 0.0 6.2 8.7 0.0 0.0 0.0 1.2 0.0 0.1 5.3 7.9 0.0 2.8 0.0 0.1 0.0 0.0 0.0 14.9 0.1 8.0 0.5 3.0 9.7 0.0 0.8 0.9 8.7 1.1 2.8 0.0 0.0 0.0 3.2 6.2 7.6 6.9 12.6 7.0 9.7 5.8 13.0 6.2 4.5 14.0 6.3 0.4 12.8 12.2 16.3 1.6 0.9 4.8 0.5 1.2 10.6 18.1 10.8 7.5 8.6 6.1 23.9 4.2 4.9 4.2 1.9 1.9 11.6 0.7 15.3 0.8 0.4 8.3 0.0 24.6 7.5 2.9 4.2 2.0 5.4 4.5 4.0 0.4 0.1 0.4 10.1 14.5 2.8 2.0 0.0 0.4 3.8 2.8 0.5 0.0 1.9 0.6 100.1 23.7 9.0 10.5 2.2 2.3 12.0 0.1 12.0 1.7 16.3 47.3 3.4 6.6 25.7 1.8 0.5 2.4 1.1 0.6 0.3 3.2 21.2 2.9 3.3 ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 11 "U-698: 8664.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 700000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: AB_2681425" "unprognostic (6.27e-2)" "prognostic favorable (8.24e-4)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (2.58e-1)" "unprognostic (8.24e-2)" "unprognostic (1.94e-3)" "unprognostic (1.82e-1)" "unprognostic (2.02e-1)" "unprognostic (1.44e-3)" "unprognostic (1.21e-1)" "unprognostic (5.40e-2)" "unprognostic (2.21e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (7.64e-2)" "unprognostic (8.07e-3)" 140.5 106.6 151.2 115.1 156.7 219.8 154.9 133.6 188.2 145.2 132.6 135.9 133.6 117.8 183.3 288.0 100.5 94.9 120.2 161.6 144.1 118.8 148.8 124.0 128.4 137.2 135.6 102.4 108.5 173.0 92.0 103.7 134.2 97.7 123.9 121.8 122.9 94.6 301.0 241.3 132.7 105.8 136.9 99.7 124.1 45.2 147.4 157.8 134.4 212.3 146.7 147.0 165.6 157.0 287.1 170.8 236.9 206.9 149.7 126.8 220.7 141.0 148.4 199.9 171.7 207.3 216.6 288.9 196.8 122.1 125.1 238.3 198.5 325.4 160.1 415.1 277.4 434.3 239.6 158.2 108.3 372.1 462.6 100.5 202.0 214.1 293.6 118.8 206.2 224.8 321.7 551.8 140.9 775.5 302.3 272.6 431.2 386.2 211.1 298.6 199.9 328.0 299.2 306.0 303.8 193.3 201.6 385.6 222.1 200.8 533.9 442.9 208.2 143.9 261.9 171.8 340.3 309.4 441.4 8664.2 197.1 357.6 191.8 67.3 54.4 94.3 55.6 62.9 52.2 64.3 46.3 57.5 70.7 55.3 37.7 56.0 53.0 68.8 64.3 58.3 58.2 75.1 151.2 156.7 133.6 188.2 161.6 144.1 137.2 135.6 134.2 136.9 147.4 157.0 103.1 41.7 166.1 20.9 132.9 190.3 225.1 303.9 124.7 59.7 152.7 117.1 102.6 98.7 172.9 82.8 45.9 286.5 148.9 170.7 254.3 160.3 9.7 109.1 68.5 114.2 130.8 178.2 44.7 152.4 184.2 85.9 71.9 93.7 224.3 51.1 80.3 86.9 203.3 67.3 29.3 169.1 211.6 101.1 171.4 17.7 86.0 123.3 103.2 19.7 409.7 83.6 184.4 21.6 19.3 91.5 146.8 104.2 135.6 128.0 187.2 186.0 128.8 50.0 72.3 85.5 94.4 27.6 25.0 269.7 286.8 382.8 140.4 87.9 163.9 253.7 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.9;pancreas: 149.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.8;Excitatory neurons: 79.7;Hepatocytes: 125.2;Proximal enterocytes: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 31.7;hTCEpi: 49.8;OE19: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" 21.0 9.7 6.0 4.5 8.7 0.0 15.3 2.0 12.2 4.1 11.8 57.6 47.6 1.2 17.9 1.5 10.8 4.2 8.8 10.7 6.4 6.4 88.9 6.3 0.2 2.7 5.3 13.8 149.1 11.1 1.6 2.5 3.7 7.6 56.7 3.0 26.9 9.1 6.1 15.5 51.9 1.9 7.2 0.1 30.6 7.5 10.9 0.6 44.7 0.7 1.6 2.2 3.4 4.3 8.7 10.8 0.7 0.8 0.8 0.0 31.7 1.1 0.4 3.7 1.9 18.5 8.5 0.0 2.3 1.0 8.9 13.9 21.5 11.5 3.9 9.2 5.1 0.0 3.4 26.5 2.2 0.4 0.0 0.3 49.8 1.5 17.0 1.1 0.2 8.0 0.3 0.0 5.2 22.3 0.4 0.2 13.8 62.8 15.7 0.0 0.0 0.6 12.9 13.1 13.1 1.4 3.4 22.2 0.0 6.3 5.2 0.1 0.5 7.5 7.6 2.5 3.1 0.1 0.1 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 8.7 2.0 12.2 10.7 6.4 2.7 5.3 3.7 7.2 10.9 4.3 0.2 6.4 5.1 2.6 0.4 11.5 5.4 6.0 1.2 7.5 22.7 10.4 18.5 20.0 9.6 7.3 0.0 4.1 0.0 134.8 0.0 3.5 11.7 23.8 2.3 0.8 51.6 0.0 79.7 20.8 2.1 2.5 26.0 20.7 0.0 6.2 5.0 125.2 0.6 38.7 58.9 51.4 12.2 1.6 1.5 1.9 13.4 0.4 1.8 3.7 0.0 1.9 0.0 12.1 3.8 10.2 54.4 2.6 0.0 7.2 79.2 0.8 39.2 1.1 0.0 0.8 1.0 1.4 17.2 0.9 24.0 1.9 0.5 6.8 46.5 6.5 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPS8L2 "FLJ21935, FLJ22171, MGC3088" ENSG00000177106 "EPS8 like 2" Q9H6S3 11 694438-727727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 188.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 211.4;Paneth cells: 175.3;Proximal enterocytes: 235.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 3.1" "Lineage enriched" "Detected in single" 8 "dendritic cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 234.3;BEWO: 220.8;CAPAN-2: 206.6;SK-BR-3: 257.5" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 10 "cerebellum: 9.2" HPA041143 Approved Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "HPA041143: AB_10794985" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (7.58e-2)" "unprognostic (3.40e-2)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.87e-2)" "unprognostic (3.27e-2)" "unprognostic (1.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (2.54e-1)" "unprognostic (1.92e-1)" "unprognostic (3.25e-2)" "unprognostic (2.51e-2)" "unprognostic (4.19e-1)" "unprognostic (2.79e-1)" "unprognostic (5.03e-2)" 7.8 11.2 5.2 5.7 4.8 0.0 27.0 8.9 5.5 49.4 4.9 42.7 100.8 11.4 3.5 188.5 19.2 13.3 4.3 4.5 6.8 98.4 101.7 32.4 0.7 10.9 9.2 11.8 43.7 3.8 11.5 17.7 6.2 29.3 15.5 1.0 94.6 15.2 1.3 76.3 105.0 2.9 7.1 1.4 48.1 3.2 7.1 2.0 70.2 0.4 10.9 17.5 80.1 6.5 234.3 68.6 0.2 1.6 2.7 14.4 220.8 20.1 20.3 29.2 12.5 51.4 206.6 0.4 81.6 21.4 5.4 122.4 0.6 117.8 6.4 0.6 5.4 0.0 27.7 94.7 16.3 0.3 0.4 8.1 77.8 8.0 18.7 12.3 0.2 0.1 1.8 1.1 3.2 72.1 0.5 1.3 2.7 71.5 24.0 0.5 0.8 1.8 103.8 55.2 0.8 0.8 75.9 257.5 0.5 14.3 94.9 0.2 1.5 11.2 27.3 7.2 1.6 0.9 1.0 0.8 6.1 0.6 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.1 5.2 4.8 8.9 5.5 4.5 6.8 10.9 9.2 6.2 7.1 7.1 6.5 1.8 141.1 51.8 3.9 11.2 19.8 26.2 48.8 51.8 0.6 39.1 37.0 4.5 57.2 62.4 90.1 0.0 47.9 21.6 211.4 27.4 55.2 1.0 47.3 7.1 4.7 43.8 1.3 3.1 80.0 33.4 11.5 131.0 60.8 7.0 0.4 0.7 59.4 4.7 0.0 3.8 76.8 32.6 2.1 7.8 2.3 18.0 2.7 14.2 2.8 3.1 10.0 16.5 2.0 0.7 83.2 175.3 11.7 7.6 33.6 235.9 108.2 60.9 1.5 0.0 0.9 7.5 1.1 4.8 74.9 24.4 92.5 18.6 0.9 77.2 32.1 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ERG28 "C14orf1, NET51" ENSG00000133935 "Ergosterol biosynthesis 28 homolog" Q9UKR5 14 75649791-75660876 "Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 152.0;Ductal cells: 95.4;Exocrine glandular cells: 110.3;Extravillous trophoblasts: 154.2;Syncytiotrophoblasts: 116.3;Theca cells: 121.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043172 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" "HPA043172: AB_10793942" "unprognostic (2.68e-3)" "unprognostic (2.11e-2)" "unprognostic (4.55e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (1.34e-3)" "unprognostic (6.25e-2)" "unprognostic (7.66e-2)" "unprognostic (4.64e-1)" "unprognostic (2.66e-2)" "unprognostic (2.47e-1)" "unprognostic (3.01e-2)" "prognostic favorable (4.30e-5)" "unprognostic (1.28e-1)" "unprognostic (2.77e-1)" "unprognostic (9.58e-3)" "unprognostic (2.20e-1)" 9.8 27.7 24.0 9.1 23.3 13.2 17.3 24.6 26.2 16.9 25.1 16.5 21.6 14.9 40.6 34.6 16.9 11.9 13.6 24.6 25.0 18.5 70.2 22.6 11.5 26.2 25.2 20.0 16.1 29.7 17.4 14.9 25.4 21.2 15.5 19.4 19.9 13.8 10.3 24.8 14.5 14.6 25.4 8.3 13.6 47.1 25.8 10.2 21.5 11.3 14.6 12.5 20.1 27.5 39.2 21.6 42.7 33.5 28.6 53.1 26.6 15.6 48.2 29.9 51.0 33.8 91.4 16.6 22.3 19.6 59.7 42.4 38.5 67.0 34.0 31.2 25.4 17.8 20.5 48.4 41.4 19.7 25.5 66.5 56.7 42.9 23.8 24.0 35.3 44.7 16.0 39.3 20.9 77.7 30.2 21.8 41.8 62.5 34.7 23.9 28.7 33.0 99.8 50.5 36.6 20.1 39.2 33.5 24.1 37.8 56.1 28.3 25.1 16.1 32.0 15.8 15.8 25.3 32.5 36.1 25.7 28.5 27.7 33.5 12.3 20.0 40.0 12.7 39.5 39.4 43.1 41.8 29.8 34.5 39.1 38.5 6.6 31.8 13.2 38.4 42.7 31.9 24.0 23.3 24.6 26.2 24.6 25.0 26.2 25.2 25.4 25.4 25.8 27.5 18.8 22.4 57.5 0.0 9.3 0.0 0.0 0.0 0.0 0.0 74.7 57.7 0.0 0.0 11.2 60.7 0.0 152.0 23.6 0.0 49.0 95.4 0.0 43.4 11.5 18.0 0.0 0.0 0.0 110.3 154.2 21.4 0.0 30.3 5.1 63.2 0.0 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 37.7 0.0 0.0 0.0 0.0 76.9 0.0 0.0 3.5 0.0 0.0 47.1 18.2 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 116.3 12.4 121.2 0.0 0.0 ERGIC3 "C20orf47, CGI-54, Erv46, NY-BR-84, PRO0989, SDBCAG84" ENSG00000125991 "ERGIC and golgi 3" Q9Y282 20 35542038-35557634 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 711.0;Late spermatids: 708.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015242, HPA015968" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA015242: AB_1848238, HPA015968: AB_1848239" "unprognostic (4.36e-2)" "unprognostic (3.43e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (2.20e-7)" "unprognostic (2.61e-1)" "unprognostic (2.90e-2)" "unprognostic (9.59e-2)" "unprognostic (8.59e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (9.81e-5)" "unprognostic (9.53e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-1)" "unprognostic (8.64e-2)" 123.3 167.5 123.4 77.7 124.6 164.5 174.9 124.4 180.6 161.8 183.3 154.6 124.2 127.4 456.9 146.9 325.4 135.1 123.8 123.8 131.5 145.3 181.0 115.1 99.4 128.2 129.9 188.3 270.3 188.0 86.9 151.3 128.2 125.9 190.9 67.0 196.9 142.3 103.5 151.4 110.4 142.6 124.7 108.3 162.0 211.6 133.9 119.9 199.8 95.2 154.6 154.0 137.5 128.2 173.2 317.5 161.8 282.4 553.6 417.1 210.1 234.4 503.7 378.3 374.0 726.9 354.2 127.4 214.4 495.4 332.8 249.5 137.7 371.9 279.0 62.8 252.5 272.6 221.1 453.2 285.2 240.1 193.2 462.8 578.1 235.1 298.7 432.5 251.1 163.0 189.8 399.3 307.0 379.1 191.4 354.0 93.4 645.1 305.1 143.1 378.8 365.5 315.6 298.7 155.4 225.5 353.4 286.0 284.7 159.8 276.5 389.0 209.8 429.5 169.0 178.0 208.1 164.7 107.0 102.5 461.2 126.4 235.5 98.5 188.7 106.7 117.9 182.2 143.3 157.9 139.2 130.4 228.7 146.6 136.0 139.9 62.0 150.7 158.9 226.6 177.0 237.8 123.4 124.6 124.4 180.6 123.8 131.5 128.2 129.9 128.2 124.7 133.9 128.2 48.1 35.3 79.9 14.4 107.1 184.2 209.7 289.4 150.2 27.1 194.3 150.2 37.1 153.0 190.7 62.5 18.8 476.5 80.6 224.5 117.4 210.6 711.0 215.5 99.4 101.8 112.6 93.2 8.9 269.8 490.7 122.7 114.7 77.5 78.0 94.7 146.3 146.4 208.1 16.8 10.1 246.9 152.5 148.2 192.5 708.4 105.3 100.4 190.3 8.4 126.7 76.8 82.4 8.0 13.6 185.0 283.1 94.0 344.1 189.8 213.4 207.5 340.2 31.3 118.3 100.5 122.0 415.9 170.5 172.6 200.6 589.4 86.8 111.3 264.6 292.3 ERI3 "FLJ22943, PINT1, PRNPIP" ENSG00000117419 "ERI1 exoribonuclease family member 3" O43414 1 44221070-44355260 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 943.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027147, HPA029895" Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA027147: AB_1855725, HPA029895: AB_2673239" "unprognostic (1.31e-1)" "unprognostic (2.39e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.18e-4)" "unprognostic (5.94e-2)" "unprognostic (6.21e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (6.48e-2)" "unprognostic (2.67e-1)" "unprognostic (6.70e-3)" "unprognostic (5.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (2.07e-1)" "unprognostic (7.47e-2)" "unprognostic (1.08e-1)" "unprognostic (2.07e-3)" 31.1 34.8 105.3 15.5 105.9 24.6 30.5 92.0 140.3 30.1 92.2 34.4 20.6 33.3 34.2 27.9 37.2 20.5 51.7 111.9 98.7 59.8 41.8 25.6 19.3 99.4 108.1 32.4 35.0 45.2 45.1 23.3 122.2 38.8 23.2 22.4 27.8 25.2 77.2 36.1 22.7 28.6 97.2 26.4 28.9 63.3 105.7 24.1 31.2 60.2 20.4 32.2 27.2 103.4 73.6 56.5 69.3 77.7 44.9 55.5 46.0 44.0 61.4 82.1 75.1 37.8 78.3 52.3 76.4 58.7 42.2 41.2 62.6 80.6 55.9 56.9 115.8 60.0 90.2 52.0 67.9 59.3 32.8 57.9 76.9 66.2 91.3 61.0 57.3 59.5 56.4 43.9 55.2 51.2 68.7 57.0 82.2 72.2 83.7 62.6 62.4 75.3 65.2 38.9 120.5 54.9 52.5 71.3 87.7 55.1 46.6 50.1 34.1 54.3 56.5 60.7 72.0 37.7 50.1 56.4 67.7 52.4 70.4 17.6 25.8 15.8 25.5 36.4 27.2 30.8 21.1 24.5 40.3 30.9 24.8 26.0 2.4 26.1 37.3 30.3 29.4 26.2 105.3 105.9 92.0 140.3 111.9 98.7 99.4 108.1 122.2 97.2 105.7 103.4 35.4 25.6 16.5 74.4 26.2 31.6 36.5 64.7 27.3 22.6 36.2 51.3 15.1 15.7 26.2 29.5 2.1 93.2 19.3 31.2 97.8 56.9 202.7 35.3 30.7 27.4 118.3 26.5 36.7 62.5 85.9 39.8 25.0 23.1 15.2 62.8 18.9 22.3 45.0 25.2 34.0 99.1 46.8 19.2 27.2 943.6 36.4 20.1 48.0 38.4 27.9 42.6 15.5 66.4 54.5 37.7 22.2 36.5 28.3 51.0 17.0 167.3 20.4 16.4 6.6 28.5 52.0 68.0 51.4 29.4 34.5 61.6 20.2 54.0 37.1 30.7 ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787044-53818819 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA031501: AB_10600104, HPA031502: AB_10602174, HPA031503: AB_10670425" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (3.17e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.27e-3)" "unprognostic (3.79e-1)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" 38.4 51.0 30.2 31.3 32.1 33.8 48.7 29.3 41.9 66.4 39.3 45.8 37.7 40.9 93.9 26.1 36.2 41.0 45.2 32.9 39.2 38.1 43.4 44.1 32.4 28.7 31.1 38.0 67.1 57.3 59.4 56.6 31.5 72.8 50.2 54.5 54.0 55.9 32.1 20.1 34.0 38.5 30.1 33.1 55.3 42.4 31.5 28.1 72.5 39.5 41.2 44.7 27.2 34.4 42.1 47.3 44.4 27.4 123.3 111.3 65.5 100.5 109.1 49.0 51.4 31.3 55.7 29.4 94.5 106.3 86.3 29.7 29.2 42.3 62.1 67.0 38.7 36.1 29.1 93.8 84.4 60.2 63.9 70.5 69.4 51.6 83.3 99.4 58.1 28.6 39.0 115.8 73.6 35.3 27.7 48.0 34.1 67.1 30.4 24.9 53.1 82.7 57.7 39.3 26.5 46.3 36.6 79.0 64.6 50.3 38.0 45.9 63.3 53.9 47.2 44.0 60.3 170.1 120.3 16.5 88.2 35.8 64.5 77.0 25.1 30.7 41.4 27.8 45.8 36.8 36.3 39.9 28.0 28.6 33.9 39.0 9.6 45.4 33.3 40.1 36.6 41.5 30.2 32.1 29.3 41.9 32.9 39.2 28.7 31.1 31.5 30.1 31.5 34.4 57.2 89.8 116.7 22.2 86.3 25.1 42.5 88.0 34.1 77.0 76.3 54.6 83.5 52.9 93.5 66.2 31.3 100.2 60.9 43.4 33.2 76.1 168.4 67.7 77.5 63.8 55.1 23.1 24.0 115.7 105.8 99.7 54.6 101.7 74.1 36.6 68.6 81.8 60.1 95.9 28.5 169.7 107.8 39.7 31.5 117.9 88.3 41.7 80.0 17.8 61.7 79.7 72.1 20.6 25.3 90.2 42.8 84.2 394.0 113.4 32.3 51.4 118.2 68.6 52.6 55.6 109.5 146.1 65.3 40.3 33.4 183.6 57.0 48.3 57.1 67.5 ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "CAB014894: , HPA002025: AB_1080077" "unprognostic (5.82e-3)" "unprognostic (2.45e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.39e-2)" "unprognostic (1.89e-1)" "unprognostic (3.77e-2)" "unprognostic (6.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.78e-3)" "prognostic favorable (6.67e-6)" "unprognostic (4.78e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "unprognostic (2.33e-1)" 20.3 17.8 15.7 14.6 17.3 14.4 25.0 16.5 16.8 20.0 27.2 24.2 17.7 21.2 32.3 17.9 30.1 19.8 17.8 14.2 16.3 40.4 40.8 15.5 11.5 18.0 18.5 30.8 26.2 41.4 8.3 21.2 17.7 25.4 25.0 21.6 29.4 23.8 18.9 15.3 23.6 19.5 17.9 14.6 24.9 17.0 15.6 14.7 46.5 14.1 12.6 16.8 10.3 18.6 39.0 38.5 43.0 31.4 47.3 33.9 47.2 59.1 51.9 31.8 33.2 20.1 50.8 18.9 95.8 63.4 30.3 41.4 31.2 48.4 46.8 11.2 24.2 27.8 22.7 22.7 31.5 17.8 34.1 43.3 49.1 46.3 48.1 39.6 30.7 17.2 51.1 17.7 47.4 18.3 25.8 14.7 45.9 53.8 17.7 17.9 29.9 15.2 42.8 41.9 7.7 20.7 39.3 12.6 35.6 50.1 62.0 27.1 31.1 30.9 26.4 56.8 31.1 24.3 41.0 24.2 55.0 28.4 40.7 1.3 6.5 13.4 4.4 7.0 3.6 4.5 2.7 3.5 5.4 2.3 4.1 3.8 6.1 2.5 9.6 7.6 5.5 3.1 15.7 17.3 16.5 16.8 14.2 16.3 18.0 18.5 17.7 17.9 15.6 18.6 14.7 12.8 14.3 21.5 7.1 9.7 10.0 18.5 13.1 25.2 24.9 20.7 30.2 25.8 22.8 33.1 20.9 17.9 6.0 19.0 9.8 23.8 21.3 31.3 18.5 13.6 11.4 8.0 3.7 22.1 27.0 18.8 17.3 27.8 3.8 14.4 17.5 41.0 20.6 16.8 6.4 24.3 20.3 23.9 6.6 16.8 11.8 16.1 14.2 7.5 12.3 23.5 5.2 11.6 16.7 18.8 17.4 17.7 16.8 15.2 25.4 19.8 47.6 18.7 19.7 19.1 14.8 47.4 18.5 21.9 7.4 15.7 7.1 12.9 25.4 12.8 ERMP1 "FLJ23309, FXNA, KIAA1815" ENSG00000099219 "Endoplasmic reticulum metallopeptidase 1" Q7Z2K6 9 5765076-5833117 "Enzymes, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 50.1" "Cell type enhanced" "Detected in many" "Collecting duct cells: 73.5;Granulosa cells: 53.4;Oligodendrocytes: 88.8;Urothelial cells: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 76.8;RT4: 154.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055582 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA055582: " "unprognostic (1.93e-2)" "unprognostic (3.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.93e-2)" "unprognostic (2.97e-1)" "unprognostic (8.59e-2)" "unprognostic (4.30e-3)" "unprognostic (2.81e-1)" "unprognostic (5.46e-2)" "unprognostic (4.83e-3)" "unprognostic (3.14e-2)" "unprognostic (2.88e-2)" "prognostic favorable (5.83e-10)" "unprognostic (1.41e-1)" "unprognostic (4.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.36e-1)" 3.9 7.9 4.2 3.7 10.4 2.0 6.3 10.9 3.7 10.8 14.4 11.3 4.4 5.6 2.6 14.9 6.4 11.3 10.0 2.9 6.1 24.9 4.6 6.3 3.5 10.1 10.3 4.5 3.9 50.1 1.5 7.8 8.8 6.0 11.4 2.2 19.1 4.1 7.6 9.3 6.5 3.8 6.5 3.1 13.3 4.7 8.9 4.6 26.6 9.9 6.4 17.1 4.8 13.1 45.1 43.1 1.8 5.2 22.6 20.7 22.6 5.1 11.1 2.3 1.9 10.4 27.2 10.7 19.2 8.4 25.9 32.2 9.6 29.4 3.3 55.6 7.6 56.2 20.0 20.4 4.8 16.0 21.3 10.5 12.9 2.1 13.3 28.6 30.1 4.6 6.9 9.9 2.8 20.7 0.6 6.2 6.6 28.0 8.4 1.7 5.3 14.1 76.8 154.6 9.9 3.3 7.1 52.2 8.1 24.5 33.7 20.5 18.0 1.5 5.0 3.4 16.1 8.9 13.6 5.5 6.7 13.0 4.1 0.2 0.1 0.3 0.4 0.1 0.6 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.0 0.1 0.1 0.1 4.2 10.4 10.9 3.7 2.9 6.1 10.1 10.3 8.8 6.5 8.9 13.1 3.4 6.4 1.1 24.8 2.2 2.9 18.3 13.3 2.8 4.0 11.1 5.8 13.7 12.8 22.8 73.5 10.4 6.8 5.2 32.1 0.0 4.6 22.3 11.4 10.9 6.3 11.4 6.3 21.0 3.0 7.1 4.6 13.7 13.8 8.9 53.4 2.9 6.1 5.7 3.3 32.8 8.9 10.2 1.6 2.2 41.8 3.1 4.5 1.8 24.4 2.1 3.0 8.2 22.1 88.8 3.5 22.5 4.9 4.1 7.0 9.2 3.3 16.6 2.9 6.6 5.8 4.3 8.8 4.6 17.5 4.5 4.1 5.9 39.8 15.7 66.9 ERP29 "C12orf8, ERp28, ERp31, PDI-DB, PDIA9" ENSG00000089248 "Endoplasmic reticulum protein 29" P30040 12 112013348-112023449 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039363, HPA039456" Enhanced Uncertain Nucleoplasm,Microtubules "Intracellular and membrane" NA NA 900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Microtubules Nucleoplasm "HPA039363: AB_10673422, HPA039456: AB_10672963" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.43e-5)" "unprognostic (1.13e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (1.04e-2)" "unprognostic (2.00e-1)" "unprognostic (1.21e-1)" "unprognostic (5.10e-3)" "unprognostic (2.58e-1)" "unprognostic (3.21e-1)" "unprognostic (2.74e-3)" "unprognostic (3.34e-1)" "unprognostic (1.76e-1)" "unprognostic (6.26e-2)" 62.7 100.9 56.9 77.9 58.0 202.3 84.0 65.1 62.0 78.4 91.1 94.5 100.7 60.5 109.8 91.5 74.8 64.1 59.0 56.0 68.7 93.0 179.9 78.8 123.8 61.1 62.6 78.9 174.6 123.6 99.1 73.0 64.2 93.4 91.3 68.3 122.7 87.4 34.3 113.3 96.1 47.1 57.8 118.3 131.4 57.6 60.8 107.6 90.4 34.3 111.2 75.9 71.0 61.6 145.4 137.2 98.8 194.2 367.4 143.7 211.3 139.2 163.7 108.5 139.3 215.2 164.4 152.7 106.4 244.5 117.8 175.4 187.8 181.2 89.3 133.7 104.2 174.3 150.1 239.2 246.8 432.1 164.0 207.5 227.6 178.4 201.6 287.4 156.1 157.9 203.2 277.3 84.7 166.6 140.9 765.7 161.5 513.1 102.5 114.2 120.9 501.2 229.8 213.5 88.6 119.8 173.6 140.1 426.1 187.4 177.1 575.7 116.5 92.6 142.7 88.8 103.3 303.4 379.8 128.0 157.8 268.5 73.2 96.2 241.4 346.2 131.6 178.8 140.4 259.1 170.7 164.1 229.7 264.1 186.5 154.9 47.5 86.5 170.9 455.8 179.6 307.4 56.9 58.0 65.1 62.0 56.0 68.7 61.1 62.6 64.2 57.8 60.8 61.6 102.6 83.3 183.4 13.7 324.8 141.4 205.5 249.3 132.6 125.3 207.8 199.9 91.6 198.8 178.0 185.8 110.5 497.7 396.6 210.1 93.9 239.5 7.7 142.1 84.9 114.9 197.9 134.4 14.4 211.8 405.3 118.3 131.5 149.9 88.8 164.4 146.3 346.6 373.1 80.8 20.6 280.6 343.8 306.9 192.6 16.6 128.9 230.4 168.9 12.2 269.0 152.8 160.6 11.6 22.8 128.7 288.0 106.8 350.1 195.4 355.5 274.6 187.0 164.9 52.6 79.2 112.2 100.3 195.3 143.1 161.0 441.6 221.7 252.4 285.2 219.8 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Ionocytes: 22.4;Proximal enterocytes: 22.6;Squamous epithelial cells: 7.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.4 0.2 0.0 2.4 0.0 8.5 0.5 0.0 0.0 3.5 0.0 1.5 3.9 0.2 0.0 15.4 0.2 0.4 0.1 0.0 0.0 0.9 0.6 0.4 4.4 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.1 1.4 0.0 2.0 0.1 0.0 2.6 4.3 0.7 0.0 1.0 0.9 6.2 0.1 10.7 0.1 0.0 4.9 0.6 5.9 0.0 27.8 23.6 27.6 21.1 0.6 1.9 17.5 15.9 8.6 28.8 19.2 15.8 22.7 49.9 9.5 6.8 17.4 20.2 32.6 9.9 14.3 13.7 32.8 30.6 24.1 11.1 0.1 19.5 25.2 0.6 0.6 15.5 7.6 2.8 15.4 22.2 42.6 41.0 9.1 29.2 30.6 16.4 22.5 14.5 12.9 29.3 30.2 21.4 4.2 11.6 18.9 15.8 11.9 20.4 10.1 13.0 36.9 12.7 8.2 14.5 27.2 11.9 25.5 32.5 29.7 31.9 8.2 19.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.3 0.6 0.9 0.3 0.5 0.6 0.0 1.0 1.3 0.9 0.0 0.4 3.7 0.0 1.9 0.6 2.7 0.0 0.2 0.8 0.2 0.8 1.0 3.5 1.3 0.7 0.0 2.3 1.1 3.6 0.7 0.0 4.4 0.7 6.8 2.6 0.0 0.4 2.7 22.4 0.6 2.1 1.2 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.5 1.5 1.3 0.4 2.1 0.4 22.6 6.6 0.2 0.0 0.0 0.4 0.9 5.5 4.1 7.4 0.6 0.3 0.4 0.1 2.8 0.4 ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.6;parathyroid gland: 46.3;retina: 36.1;stomach 1: 35.1" "Group enriched" "Detected in many" 4 "Astrocytes: 330.7;Excitatory neurons: 415.2;Inhibitory neurons: 495.5;Oligodendrocyte precursor cells: 391.6;Oligodendrocytes: 218.7;Syncytiotrophoblasts: 214.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "RPMI-8226: 23.0;SH-SY5Y: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044678: AB_10963215" "unprognostic (6.48e-2)" "unprognostic (1.11e-1)" "unprognostic (7.06e-2)" "unprognostic (7.32e-2)" "unprognostic (2.34e-1)" "unprognostic (5.48e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (4.55e-2)" "unprognostic (2.88e-1)" "unprognostic (2.35e-1)" "unprognostic (1.79e-2)" "prognostic favorable (1.13e-11)" "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.65e-4)" "unprognostic (2.05e-1)" 0.4 6.4 1.1 0.2 3.1 0.0 3.6 16.9 12.3 1.5 7.4 0.5 5.3 0.4 0.9 1.6 2.5 0.7 10.6 4.4 2.3 29.0 0.7 0.5 0.2 45.4 4.9 0.7 5.7 46.3 1.5 10.6 49.6 3.1 0.3 36.1 16.0 0.7 5.8 0.8 5.0 0.2 1.6 1.1 35.1 1.1 3.5 0.6 5.9 10.2 0.3 0.7 0.2 6.1 0.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 23.0 3.4 2.5 8.1 42.4 0.0 0.4 0.0 2.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 3.1 16.9 12.3 4.4 2.3 45.4 4.9 49.6 1.6 3.5 6.1 0.2 0.0 1.8 330.7 0.2 0.3 3.8 0.6 0.6 29.5 9.5 5.2 51.2 10.0 1.8 23.9 58.4 35.4 0.0 0.0 54.8 5.0 5.1 15.9 2.0 1.3 8.3 0.0 415.2 2.4 4.7 3.0 70.3 3.5 0.0 0.5 1.1 0.6 4.8 48.8 495.5 1.7 14.2 0.3 0.4 8.1 0.3 0.5 8.8 36.5 0.0 13.3 0.0 391.6 218.7 0.4 1.3 0.7 0.1 4.9 16.3 29.0 16.0 41.3 0.0 10.3 0.4 1.6 0.3 0.8 0.3 214.9 0.3 1.1 2.6 1.7 EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 164.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.7;Microglial cells: 146.1;Oligodendrocyte precursor cells: 157.3;Rod photoreceptor cells: 177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" 8.7 14.4 5.9 8.2 7.5 12.9 8.0 7.7 8.6 6.5 8.0 9.6 8.1 6.1 5.7 4.2 5.8 10.1 7.1 8.2 6.0 6.4 10.1 10.7 9.5 3.4 2.4 3.9 10.0 6.3 6.1 37.4 3.7 8.6 10.2 164.2 5.6 4.3 31.8 5.0 9.5 7.7 3.3 9.1 7.0 9.9 6.1 8.5 28.4 19.7 8.2 10.1 3.5 7.1 19.8 24.3 25.7 16.8 1.3 1.6 9.1 9.0 24.9 8.1 9.7 9.1 16.5 22.5 19.0 4.3 6.6 12.3 20.8 5.7 10.1 20.1 20.9 35.1 8.3 11.7 9.6 36.4 30.6 2.2 3.0 7.2 4.8 14.6 113.8 14.6 29.2 14.5 4.0 10.7 15.3 23.2 3.5 40.2 7.0 22.5 11.2 11.6 17.4 13.2 8.5 11.9 9.2 9.2 11.8 6.4 18.2 18.8 22.4 0.6 8.2 7.5 14.7 10.8 12.4 18.1 2.8 41.6 9.3 6.2 4.9 15.2 3.0 3.9 3.0 6.7 3.4 2.8 5.1 6.6 2.7 3.2 30.6 2.8 3.9 11.1 3.3 2.4 5.9 7.5 7.7 8.6 8.2 6.0 3.4 2.4 3.7 3.3 6.1 7.1 28.3 16.0 16.7 33.6 27.6 3.3 10.7 8.6 3.4 40.2 9.8 6.5 12.0 20.0 15.0 16.5 39.6 22.9 24.1 14.3 5.9 28.3 5.4 8.8 3.0 53.1 25.6 39.2 181.7 15.4 7.8 7.8 13.7 16.5 10.8 24.3 77.1 14.2 21.4 23.5 100.3 16.6 14.2 18.2 12.5 12.6 4.4 18.9 5.4 146.1 22.8 27.1 19.6 157.3 84.7 14.1 10.3 14.7 13.8 14.1 10.8 8.4 10.0 177.8 13.1 13.6 9.0 25.0 25.5 4.9 4.8 20.5 18.4 29.8 11.9 15.8 F13A1 F13A ENSG00000124491 "Coagulation factor XIII A chain" P00488 6 6144084-6321013 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 232.8;placenta: 489.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 863.3;Langerhans cells: 205.1;Macrophages: 232.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 141.1;myeloid DC: 179.6" "Group enriched" "Detected in many" 184 "dendritic cells: 179.6;granulocytes: 50.2;monocytes: 141.1" "Cell line enhanced" "Detected in some" "AF22: 24.0;LHCN-M2: 8.9;RH-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA001804, CAB002155" Enhanced "Secreted to blood" NA NA 1400000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 4: Macrophages - Innate immune response" "CAB002155: AB_564077, HPA001804: AB_1078792" "unprognostic (4.44e-1)" "unprognostic (5.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (5.02e-2)" "unprognostic (3.75e-2)" "unprognostic (5.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (6.84e-3)" "unprognostic (4.96e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (6.61e-6)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (2.54e-3)" 232.8 57.9 2.6 52.3 4.2 16.1 46.9 1.3 13.0 50.4 28.5 45.9 9.7 18.5 5.6 51.2 29.1 52.7 39.2 2.1 3.6 21.0 3.0 38.7 30.0 8.3 4.6 10.7 10.0 13.3 8.1 489.2 6.9 8.8 63.9 21.6 18.8 13.4 10.3 22.7 22.0 89.6 2.6 8.8 25.4 17.8 3.7 20.9 17.1 32.8 12.5 144.5 12.1 4.0 0.0 0.1 24.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.9 0.0 0.1 0.2 0.0 0.0 0.0 0.0 43.8 0.8 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 50.2 141.1 1.4 0.5 25.4 0.6 0.4 0.3 0.4 179.6 0.4 0.4 0.2 32.9 0.3 0.7 12.5 0.3 364.9 2.6 4.2 1.3 13.0 2.1 3.6 8.3 4.6 6.9 2.6 3.7 4.0 2.0 0.0 1.9 0.3 1.8 18.7 0.0 0.0 0.6 0.1 0.3 0.4 10.6 5.7 0.0 0.0 0.0 5.0 4.5 0.0 0.0 0.0 5.1 0.6 10.6 3.8 0.0 1.3 3.9 0.0 5.6 13.7 0.0 0.4 1.3 0.0 2.9 0.9 863.3 0.0 1.4 0.0 0.0 92.4 205.1 5.8 4.4 232.0 19.6 64.6 53.1 0.9 6.2 0.5 0.7 0.1 0.0 0.7 1.2 0.0 0.0 11.0 2.2 6.5 59.2 2.5 3.3 1.6 0.9 1.2 15.2 10.1 2.6 0.4 0.0 0.1 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM107A "DRR1, TU3A" ENSG00000168309 "Family with sequence similarity 107 member A" O95990 3 58564117-58627610 "Predicted intracellular proteins" "Cell cycle, Growth regulation, Stress response" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "brain: 1923.8;choroid plexus: 1389.1" "Cell type enhanced" "Detected in many" "Adipocytes: 196.3;Astrocytes: 81.9;Endothelial cells: 121.3;Hepatic stellate cells: 150.6;Muller glia cells: 125.0" "Cancer enriched" "Detected in many" 6 "glioma: 110.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 20.7;HUVEC TERT2: 64.9" "Low region specificity" "Detected in all" HPA055888 Enhanced Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "HPA055888: AB_2682957" "unprognostic (1.20e-2)" "unprognostic (1.19e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (3.11e-1)" "unprognostic (7.80e-3)" "prognostic favorable (3.38e-4)" "unprognostic (1.92e-1)" "unprognostic (1.64e-1)" "unprognostic (5.73e-2)" "unprognostic (7.82e-3)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-2)" "unprognostic (2.82e-1)" "unprognostic (1.92e-1)" "unprognostic (7.95e-3)" 73.2 7.5 1824.7 8.3 1801.2 0.3 58.6 1490.8 1923.8 34.5 1389.1 36.9 5.4 36.3 53.3 29.2 87.0 16.0 140.4 1745.7 1736.7 45.0 5.5 93.2 3.1 1611.9 1644.5 11.8 23.3 5.9 109.6 29.4 1613.0 80.5 16.0 85.1 40.6 38.0 26.3 23.3 45.2 42.5 1564.5 25.7 37.7 5.7 1698.7 43.9 51.4 32.8 8.6 68.9 41.6 1770.4 0.0 0.0 0.9 0.0 20.7 1.3 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 1.4 0.0 0.1 0.1 0.3 64.9 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.2 0.0 3.6 0.3 0.2 0.2 0.1 0.1 0.0 0.1 1.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1824.7 1801.2 1490.8 1923.8 1745.7 1736.7 1611.9 1644.5 1613.0 1564.5 1698.7 1770.4 196.3 6.4 5.5 81.9 0.5 2.2 50.8 0.3 2.2 5.2 2.3 1.3 26.5 4.3 3.2 38.6 52.1 0.1 0.4 0.0 9.8 1.1 14.5 23.2 2.4 121.3 3.6 2.7 1.4 0.2 0.0 18.4 0.0 39.3 1.3 5.9 150.6 1.6 0.0 3.3 5.3 0.0 0.0 2.2 3.7 32.4 32.9 1.9 5.4 14.0 0.0 125.0 0.0 2.0 0.6 0.3 0.0 11.7 1.3 7.3 0.2 4.5 2.3 50.2 6.6 6.6 10.4 0.7 0.4 0.4 2.7 0.0 1.0 0.5 0.0 2.2 FAM162A "C3orf28, E2IG5" ENSG00000114023 "Family with sequence similarity 162 member A" Q96A26 3 122384176-122412334 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 625.3;Distal tubular cells: 540.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035856, HPA075611" Approved Supported Mitochondria NA NA 19000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA035856: AB_10611965, HPA075611: " "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (7.84e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (5.91e-3)" "unprognostic (8.74e-2)" "unprognostic (1.95e-2)" "unprognostic (7.91e-3)" "unprognostic (4.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.06e-1)" "unprognostic (4.10e-2)" "prognostic favorable (3.93e-4)" 49.0 105.7 54.8 31.3 60.2 39.9 43.9 57.3 82.2 84.5 57.1 145.9 56.1 49.5 59.4 207.6 49.7 46.2 174.2 57.1 58.5 107.6 200.3 32.0 32.9 55.9 57.2 84.3 133.9 116.6 51.0 17.6 55.6 74.6 149.0 83.5 59.8 49.2 141.0 89.8 56.3 44.6 56.6 31.7 93.2 43.6 58.8 34.7 44.1 142.6 42.7 76.9 131.5 55.6 132.0 27.7 40.4 75.6 72.1 66.4 20.7 52.9 46.8 49.0 123.9 69.4 58.7 142.1 89.2 18.2 40.3 89.8 73.5 128.1 130.0 74.0 55.1 115.6 44.0 125.8 47.4 114.0 39.6 77.3 65.5 46.7 97.9 164.3 66.0 137.7 79.2 55.6 71.1 52.0 116.9 137.9 59.5 294.9 144.4 69.5 57.8 186.9 144.3 314.9 60.1 48.1 39.4 92.4 114.3 59.9 57.9 55.7 47.0 48.4 34.6 28.7 55.6 108.8 39.9 144.8 143.3 109.7 22.8 9.9 25.8 75.7 58.3 68.2 86.9 75.3 79.5 74.0 84.6 68.1 85.1 88.6 8.5 50.6 75.9 70.4 80.4 38.8 54.8 60.2 57.3 82.2 57.1 58.5 55.9 57.2 55.6 56.6 58.8 55.6 55.7 28.9 46.0 41.1 68.2 128.1 155.3 625.3 82.0 31.5 80.6 109.5 338.4 84.4 188.6 130.6 47.9 51.4 47.9 477.5 540.0 148.2 102.5 82.0 30.1 49.8 106.9 47.7 33.0 177.6 47.8 78.7 84.6 79.2 85.7 59.3 44.6 280.4 92.7 38.7 30.4 374.3 240.1 66.7 108.9 33.1 134.5 61.2 104.9 7.5 108.9 79.7 45.3 22.1 21.6 141.6 313.2 148.6 61.2 121.4 186.2 466.2 95.5 29.9 105.2 83.2 315.3 146.4 68.3 315.1 132.8 47.2 66.0 121.1 358.4 210.9 FAM169A "KIAA0888, SLAP75" ENSG00000198780 "Family with sequence similarity 169 member A" Q9Y6X4 5 74777574-74866966 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2;retina: 71.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 138.0;Cone photoreceptor cells: 141.8;Excitatory neurons: 103.4;Horizontal cells: 85.8;Inhibitory neurons: 101.3;Muller glia cells: 191.3;Rod photoreceptor cells: 179.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 31.9;Hep G2: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041574 Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nuclear membrane, Cytosol" "HPA041574: AB_10794382" "unprognostic (3.39e-1)" "unprognostic (2.25e-2)" "unprognostic (1.75e-4)" "unprognostic (5.87e-2)" "unprognostic (2.28e-2)" "unprognostic (1.46e-3)" "unprognostic (1.53e-1)" "unprognostic (7.11e-2)" "unprognostic (6.48e-2)" "unprognostic (5.11e-2)" "unprognostic (2.72e-2)" "unprognostic (8.02e-2)" "unprognostic (3.51e-3)" "unprognostic (4.57e-1)" "unprognostic (4.72e-2)" "unprognostic (1.12e-1)" "unprognostic (3.93e-2)" 0.1 2.8 13.2 0.7 14.7 1.1 0.5 4.4 12.9 1.0 0.0 1.3 0.3 2.4 18.0 0.3 2.6 2.1 1.3 9.4 27.2 4.7 2.2 0.3 1.5 14.1 10.6 2.1 1.3 5.1 2.1 0.7 9.6 4.5 2.0 71.4 1.4 4.6 0.1 0.2 0.3 0.3 17.0 1.7 1.4 12.4 17.0 5.1 7.1 0.1 1.6 3.1 0.2 17.1 8.0 7.2 4.8 6.7 0.0 0.0 31.9 1.3 2.5 5.1 5.1 3.0 5.2 0.0 3.4 0.1 13.9 5.4 10.2 15.3 5.5 5.7 11.9 2.2 1.3 23.4 0.2 0.0 0.1 0.1 16.2 1.3 7.2 0.8 0.0 7.3 0.0 0.1 3.0 2.2 7.4 0.1 12.8 1.8 4.1 10.9 3.2 0.5 4.8 12.8 2.8 3.8 12.9 5.5 1.0 21.5 5.6 1.4 0.0 0.3 4.8 0.0 5.5 17.7 18.5 0.0 0.6 0.0 0.6 0.0 0.0 0.0 1.0 0.0 1.4 0.2 0.6 0.9 0.0 0.4 1.2 1.3 0.0 0.3 0.0 0.2 0.3 0.6 13.2 14.7 4.4 12.9 9.4 27.2 14.1 10.6 9.6 17.0 17.0 17.1 0.3 0.0 0.0 32.0 5.7 0.3 6.5 2.8 1.2 138.0 1.2 1.5 1.6 1.5 3.5 49.7 141.8 5.4 14.2 1.6 3.9 1.9 15.5 8.5 1.9 2.6 3.5 1.3 103.4 0.0 0.5 1.5 6.6 10.9 1.3 24.7 0.0 4.1 0.5 85.8 101.3 1.3 2.0 1.9 0.0 29.0 5.0 0.7 1.8 14.0 0.9 191.3 11.3 67.3 58.2 2.9 0.5 4.1 4.8 8.1 2.2 2.8 2.8 179.7 0.0 0.3 1.5 25.2 13.4 1.4 0.1 0.3 7.8 5.7 1.4 4.4 FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Intestinal goblet cells: 60.9;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cell line enhanced" "Detected in many" "CACO-2: 74.3;MCF7: 91.8;OE19: 76.3;RPMI-8226: 109.6;RT4: 221.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Intermediate filaments" "HPA015306: AB_2669182" "unprognostic (3.00e-3)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "prognostic favorable (9.03e-5)" "unprognostic (4.68e-2)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (8.23e-3)" "unprognostic (7.67e-3)" "unprognostic (5.05e-3)" "unprognostic (6.60e-2)" "unprognostic (1.33e-1)" "unprognostic (4.67e-2)" "unprognostic (2.01e-1)" "unprognostic (6.64e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-2)" 5.6 5.6 13.8 5.9 13.2 1.1 27.2 9.7 14.6 16.9 9.1 10.7 6.3 8.2 7.2 8.4 24.0 6.1 10.5 13.9 14.5 5.3 6.9 21.0 8.5 14.0 16.0 16.2 76.6 2.9 26.5 6.7 14.6 32.2 15.2 6.4 52.5 16.2 16.2 8.4 8.5 4.9 7.8 4.0 35.0 17.9 14.9 8.0 37.2 15.9 7.4 26.3 6.6 19.5 0.3 12.2 8.0 2.4 0.0 0.2 1.0 4.6 21.8 0.2 0.0 74.3 8.6 1.2 20.6 0.6 5.8 0.4 13.9 0.5 0.0 0.5 6.5 0.7 1.4 1.0 1.3 1.1 3.2 1.0 0.3 0.2 0.2 0.5 10.5 6.8 1.2 54.7 12.2 91.8 2.7 0.1 39.2 76.3 0.0 8.9 22.5 109.6 5.4 221.3 4.9 3.9 6.4 42.7 14.3 22.7 33.8 7.9 0.0 0.0 1.6 0.3 10.3 1.7 17.2 2.6 0.2 0.8 5.3 0.9 0.6 0.8 0.1 0.7 0.2 0.3 1.8 0.0 0.5 0.3 2.0 2.6 2.9 0.7 0.0 3.5 8.9 0.6 13.8 13.2 9.7 14.6 13.9 14.5 14.0 16.0 14.6 7.8 14.9 19.5 8.5 105.8 22.2 13.7 1.7 2.3 14.7 1.7 5.7 7.0 26.3 11.3 5.2 5.7 12.6 7.3 8.4 1.4 2.3 3.7 7.9 5.5 22.6 17.8 4.2 10.3 42.1 0.8 24.0 14.6 21.2 4.9 19.4 23.4 18.4 1.3 22.1 7.0 5.4 11.8 24.4 60.9 24.4 3.8 4.8 57.8 5.9 4.9 12.4 22.5 0.4 3.9 0.0 17.1 44.8 19.1 1.6 1.9 6.6 24.2 3.0 1.5 14.5 3.7 0.0 7.7 3.7 1.0 5.0 3.9 3.0 0.7 3.4 1.8 5.5 24.3 FAM199X CXorf39 ENSG00000123575 "Family with sequence similarity 199, X-linked" Q6PEV8 X 104166453-104195902 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003093 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA003093: AB_1078597" "unprognostic (2.03e-3)" "unprognostic (4.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.18e-2)" "unprognostic (1.89e-2)" "unprognostic (6.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-1)" "unprognostic (1.18e-1)" "unprognostic (9.13e-2)" "unprognostic (6.07e-3)" "unprognostic (1.08e-2)" "unprognostic (4.73e-2)" "unprognostic (4.00e-2)" "unprognostic (2.39e-2)" 19.9 11.7 17.0 7.1 16.9 13.8 11.6 18.2 18.7 9.2 10.2 8.4 7.9 10.6 34.8 7.8 9.1 6.8 7.3 15.2 18.8 15.1 7.7 8.1 8.6 15.5 19.1 11.9 11.1 19.9 8.5 9.0 17.5 10.2 8.4 16.1 10.2 13.9 9.4 9.5 7.2 8.7 16.8 8.8 8.3 10.1 20.5 9.0 17.5 9.7 7.8 8.0 7.6 18.8 23.9 14.9 13.2 14.5 9.6 11.5 13.3 12.4 11.6 15.8 14.7 11.6 19.4 13.1 15.0 11.4 12.5 17.6 23.9 18.3 25.7 6.4 13.4 10.4 19.0 13.2 13.7 20.0 14.1 9.0 22.9 15.5 15.6 24.7 16.2 8.3 11.5 28.6 17.8 17.1 10.8 14.2 13.2 20.9 17.3 11.4 8.6 16.5 26.9 15.8 7.1 8.8 30.0 19.7 21.4 12.9 9.8 9.8 20.1 17.6 6.4 13.8 13.5 13.6 12.1 14.4 19.8 21.1 13.1 0.6 0.5 0.3 0.7 0.4 0.7 0.4 0.6 0.8 0.6 1.3 0.9 0.5 0.6 0.3 0.5 0.3 0.8 0.3 17.0 16.9 18.2 18.7 15.2 18.8 15.5 19.1 17.5 16.8 20.5 18.8 18.6 16.0 14.5 33.0 17.8 24.0 11.5 12.6 13.6 23.3 21.3 14.7 13.7 17.2 12.2 62.5 14.6 11.8 23.1 23.9 23.5 11.9 0.6 20.6 27.3 15.7 16.8 9.4 25.9 18.7 13.0 11.7 18.3 31.5 9.5 16.8 14.6 18.8 17.6 33.7 24.5 17.0 16.2 21.4 27.0 3.9 11.8 15.7 10.6 15.9 14.6 20.0 22.6 26.2 21.6 15.4 18.9 14.7 20.2 14.6 14.2 34.8 10.3 16.9 26.3 17.1 13.7 4.1 9.7 21.0 26.3 14.6 15.9 21.6 15.9 15.5 FAM241B C10orf35 ENSG00000171224 "Family with sequence similarity 241 member B" Q96D05 10 69630247-69633596 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 19.4;Collecting duct cells: 16.5;Distal tubular cells: 11.7;Ductal cells: 24.3;Exocrine glandular cells: 18.4;Pancreatic endocrine cells: 20.7;Proximal tubular cells: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "gdT-cell: 4.3;MAIT T-cell: 10.9;memory CD4 T-cell: 10.5;memory CD8 T-cell: 7.0;naive CD4 T-cell: 17.2;naive CD8 T-cell: 5.7;T-reg: 7.8" "Lineage enriched" "Detected in single" 25 "T-cells: 17.2" "Cell line enhanced" "Detected in many" "PC-3: 57.5" "Low region specificity" "Detected in all" HPA034591 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Centrosome" Cytosol "HPA034591: AB_10670572" "unprognostic (1.12e-1)" "unprognostic (6.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.17e-1)" "unprognostic (7.17e-3)" "prognostic unfavorable (8.64e-4)" "prognostic unfavorable (1.03e-4)" "unprognostic (3.56e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" "unprognostic (3.37e-2)" "unprognostic (3.12e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-1)" "prognostic favorable (9.72e-4)" 1.6 3.0 26.3 1.9 27.3 1.1 4.7 30.4 40.3 2.2 19.2 6.6 2.7 3.2 11.1 4.8 4.3 2.0 6.6 35.5 31.7 10.7 3.7 4.0 2.9 21.7 24.2 2.1 8.2 8.2 12.7 1.2 28.2 7.8 2.3 11.3 5.5 4.7 4.7 3.4 3.5 3.8 21.5 1.4 5.8 22.2 26.4 2.8 5.8 1.2 2.3 5.8 3.0 22.2 29.4 31.9 3.9 31.8 0.0 0.0 13.6 2.9 0.8 5.1 5.6 23.4 23.6 0.0 42.8 0.6 18.6 11.8 16.6 9.6 7.1 29.4 22.8 0.0 6.7 8.8 8.1 0.0 10.0 0.0 9.4 0.2 4.8 3.8 0.0 43.8 11.1 0.1 0.5 39.9 0.3 0.0 19.1 11.8 57.5 0.0 0.0 0.4 10.9 16.6 16.0 22.2 12.1 29.6 19.0 7.8 20.5 5.1 1.4 0.8 19.4 0.1 8.5 5.1 15.2 0.1 0.4 0.0 0.8 0.0 0.0 0.0 4.3 0.0 10.9 0.1 10.5 7.0 0.1 0.4 17.2 5.7 0.6 0.2 0.0 0.1 7.8 3.1 26.3 27.3 30.4 40.3 35.5 31.7 21.7 24.2 28.2 21.5 26.4 22.2 1.4 0.0 4.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.3 19.4 0.0 0.0 3.1 16.5 0.0 7.5 0.6 0.0 11.7 24.3 0.0 5.7 0.4 0.7 0.0 0.0 0.0 18.4 5.6 0.6 0.0 5.0 0.0 8.6 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.3 0.0 0.0 13.5 4.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.9 2.8 3.7 0.0 0.0 FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 88.3;MCF7: 27.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064111, HPA067817" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 15: NK-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: AB_2685191, HPA067817: AB_2685904" "unprognostic (1.15e-1)" "unprognostic (7.76e-2)" "unprognostic (4.28e-2)" "unprognostic (4.43e-2)" "unprognostic (2.12e-3)" "unprognostic (2.69e-1)" "unprognostic (2.38e-2)" "unprognostic (7.13e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (2.15e-1)" "unprognostic (2.90e-1)" "prognostic favorable (4.01e-6)" "unprognostic (1.60e-1)" "unprognostic (3.22e-1)" "unprognostic (1.34e-1)" "unprognostic (9.39e-2)" 6.9 9.1 11.7 3.7 14.3 1.8 7.0 12.3 15.1 8.3 8.5 10.2 6.6 9.7 3.9 6.6 8.8 3.7 18.0 12.5 13.6 9.8 12.9 5.3 5.1 11.7 11.1 9.3 9.2 4.2 10.4 1.7 11.5 6.4 1.4 5.5 10.2 5.8 32.1 7.1 6.5 2.8 11.2 7.1 8.1 14.0 13.0 3.9 9.8 8.8 3.5 9.7 6.3 12.6 6.6 8.7 0.1 0.0 4.9 4.7 0.4 7.6 3.7 5.1 6.5 0.0 11.7 7.0 8.0 5.5 2.0 4.9 0.0 3.0 3.8 88.3 4.6 0.0 21.1 0.0 5.2 0.0 0.1 5.2 6.0 4.0 1.1 1.6 5.1 0.0 0.0 0.0 4.6 27.5 0.0 9.8 1.9 4.0 4.1 0.0 0.0 0.0 2.5 0.0 11.8 10.3 12.4 7.7 0.4 0.0 8.4 7.8 7.2 0.0 0.9 10.1 0.0 0.0 19.7 0.0 2.7 0.6 14.1 5.7 7.9 4.4 11.3 10.8 26.7 25.0 21.8 14.6 10.5 20.8 17.7 11.2 3.3 33.8 17.7 17.3 36.0 9.0 11.7 14.3 12.3 15.1 12.5 13.6 11.7 11.1 11.5 11.2 13.0 12.6 11.4 16.0 7.0 2.6 8.3 6.4 5.7 10.2 15.4 18.1 8.7 13.5 19.8 17.2 8.3 12.9 4.2 4.2 9.3 2.3 33.2 13.5 31.5 6.8 5.0 6.7 1.2 6.7 2.5 11.1 6.9 8.0 7.1 3.3 3.8 7.5 11.0 21.6 10.1 15.2 2.6 3.5 8.2 6.8 4.7 28.8 8.4 5.6 12.4 1.0 8.7 20.9 4.1 1.0 4.6 8.5 5.1 10.9 6.9 3.3 7.4 36.9 6.8 16.0 0.0 13.0 8.4 38.3 43.9 12.5 6.7 1.0 6.1 7.8 3.8 2.1 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 FARS2 "dJ236A3.1, FARS1, mtPheRS" ENSG00000145982 "Phenylalanyl-tRNA synthetase 2, mitochondrial" O95363 6 5261044-5829192 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 110.4;Early spermatids: 77.4;Excitatory neurons: 217.0;Inhibitory neurons: 122.6;Late spermatids: 78.8;Microglial cells: 106.8;Oligodendrocyte precursor cells: 186.5;Oligodendrocytes: 122.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018148, HPA028836" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA018148: AB_1848426, HPA028836: AB_10601377" "unprognostic (2.73e-1)" "unprognostic (4.08e-3)" "prognostic favorable (5.14e-4)" "unprognostic (2.68e-1)" "unprognostic (1.94e-2)" "unprognostic (5.34e-3)" "unprognostic (1.82e-1)" "unprognostic (4.31e-3)" "unprognostic (7.18e-2)" "unprognostic (1.02e-2)" "unprognostic (8.91e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.24e-6)" "unprognostic (2.81e-2)" "unprognostic (2.83e-1)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" 9.4 12.0 8.1 9.6 10.9 11.7 11.0 6.1 10.8 8.8 22.9 10.6 7.4 9.2 7.3 9.8 14.9 6.8 16.0 8.4 9.6 14.2 14.4 9.6 12.4 5.8 6.7 7.8 10.3 13.2 9.8 8.9 6.5 7.3 11.3 6.8 8.4 8.6 19.7 11.4 7.9 9.8 6.1 9.8 9.9 11.7 10.8 12.5 14.4 17.9 11.0 8.8 8.9 8.6 14.2 13.4 14.1 14.7 17.1 20.5 11.6 15.1 17.9 19.4 19.2 18.0 10.7 19.7 23.1 14.9 18.9 13.9 18.2 23.9 20.2 59.5 12.2 7.9 11.0 16.1 8.9 18.9 11.4 16.5 24.0 21.9 15.8 11.4 23.6 21.8 23.7 4.5 14.6 14.5 20.6 21.2 8.7 21.7 12.9 20.0 17.6 38.9 18.7 16.4 23.9 11.8 14.1 11.0 17.6 18.4 22.1 20.6 13.7 20.7 9.4 12.3 19.8 9.3 34.2 10.9 11.6 11.1 26.6 0.1 14.7 5.2 23.1 16.7 20.3 20.0 20.5 21.2 26.0 17.5 22.3 22.1 1.1 24.6 11.9 15.5 28.0 17.6 8.1 10.9 6.1 10.8 8.4 9.6 5.8 6.7 6.5 6.1 10.8 8.6 10.4 9.6 13.7 110.4 15.7 14.8 18.5 17.7 10.2 8.8 8.9 12.1 18.4 12.8 8.5 9.2 2.1 19.5 10.5 6.9 27.4 14.6 77.4 10.2 7.6 10.9 10.7 13.9 217.0 12.9 20.9 10.5 13.3 7.2 22.2 14.3 11.4 12.0 15.8 0.0 122.6 9.4 14.2 12.5 11.6 78.8 6.2 17.4 5.4 106.8 9.4 14.2 8.2 186.5 122.4 7.8 8.6 7.2 16.1 6.6 7.4 30.7 19.3 11.1 0.0 10.1 10.8 19.2 9.4 13.3 13.2 10.7 16.2 24.2 11.9 13.2 FASLG "APT1LG1, CD178, FasL, TNFSF6" ENSG00000117560 "Fas ligand" P48023 1 172659103-172666876 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Apoptosis, Transcription, Transcription regulation" "Cytokine, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.7" "Group enriched" "Detected in some" 14 "dendritic cells: 43.4;NK-cells: 79.3;T-cells: 28.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 58.1" "Group enriched" "Detected in many" 9 "NK-cells: 41.5;T-cells: 58.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054959 Approved "Secreted to blood" NA NA 73600 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054959: AB_2682650" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (8.69e-2)" "unprognostic (1.54e-7)" "unprognostic (3.29e-1)" "unprognostic (2.23e-3)" "unprognostic (5.44e-2)" "unprognostic (1.84e-2)" "unprognostic (4.67e-2)" "unprognostic (4.76e-2)" "unprognostic (8.88e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (3.49e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (3.82e-3)" 0.3 0.8 0.1 1.0 0.2 2.8 0.6 0.1 0.2 0.4 0.1 0.8 1.9 0.5 0.7 0.3 0.3 1.1 0.3 0.2 0.1 0.3 1.1 2.0 5.7 0.3 0.2 0.3 0.1 0.0 0.1 0.2 0.2 0.5 0.9 0.0 0.9 0.3 0.1 0.4 1.4 0.3 0.0 4.1 1.5 0.2 0.1 0.6 0.2 0.0 1.8 0.8 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 0.1 0.0 58.1 0.2 35.5 0.0 11.5 31.4 0.1 0.0 2.2 25.0 1.9 41.5 0.1 0.0 0.2 14.9 0.1 0.2 0.1 0.2 0.2 0.1 0.3 0.2 0.2 0.0 0.1 0.4 0.4 0.0 2.5 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 43.4 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.6 1.8 0.0 0.9 0.0 79.3 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 28.8 0.0 0.0 0.1 FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 270.0;Excitatory neurons: 568.2;Inhibitory neurons: 578.0;Microglial cells: 205.2;Oligodendrocyte precursor cells: 302.6;Oligodendrocytes: 256.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA036410: AB_2675109, HPA036411: AB_10669603" "unprognostic (8.15e-2)" "unprognostic (3.77e-2)" "unprognostic (2.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.58e-2)" "unprognostic (2.72e-2)" "unprognostic (2.08e-2)" "unprognostic (2.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.08e-2)" "unprognostic (5.98e-2)" "unprognostic (6.30e-2)" "prognostic favorable (4.60e-8)" "unprognostic (1.86e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (3.35e-2)" 15.4 13.8 11.8 7.8 13.1 5.9 10.4 7.5 15.3 10.8 3.8 10.1 10.6 9.9 8.9 12.0 9.0 9.1 27.0 12.4 12.5 16.9 14.2 8.9 8.5 9.0 12.2 9.3 10.0 26.0 5.7 5.9 9.0 11.8 10.4 25.6 9.8 13.7 55.8 8.7 10.9 11.7 10.5 10.7 10.1 8.6 11.8 10.1 24.6 41.7 10.7 8.5 4.5 10.3 8.7 8.5 9.6 17.7 15.8 16.4 6.4 10.4 23.3 8.4 11.3 1.7 17.9 9.7 16.0 16.9 13.0 3.8 7.7 11.9 13.0 9.8 6.9 9.2 9.0 4.2 8.2 6.2 10.1 11.8 17.4 7.8 5.7 16.3 10.1 3.9 1.3 12.2 18.5 6.5 5.4 7.9 1.3 6.7 7.9 7.6 12.8 12.7 11.7 11.9 8.2 14.0 13.6 11.9 13.4 6.6 9.4 14.6 11.0 18.9 5.9 5.9 13.6 9.5 14.3 7.0 16.7 9.4 12.6 0.1 0.1 0.8 0.4 0.2 0.4 0.2 0.4 0.4 0.2 0.3 0.4 0.3 0.3 0.2 0.1 0.4 0.2 0.1 11.8 13.1 7.5 15.3 12.4 12.5 9.0 12.2 9.0 10.5 11.8 10.3 13.2 19.2 14.5 270.0 13.9 16.8 7.4 7.5 6.8 37.2 18.6 10.2 38.3 17.2 8.3 29.5 56.3 4.8 12.8 22.8 17.6 7.3 5.6 8.5 9.7 12.3 29.9 5.7 568.2 13.1 6.5 12.1 12.2 10.7 16.5 12.2 21.0 21.4 8.4 30.3 578.0 21.7 2.0 21.0 14.1 5.4 14.0 9.9 16.0 205.2 13.1 20.8 12.3 302.6 256.1 13.3 16.0 16.6 10.7 8.6 14.4 15.0 6.1 50.4 0.0 16.6 9.8 9.5 3.9 10.6 24.6 4.5 12.6 13.8 16.6 8.8 FBXL5 "FBL4, FBL5, FLR1" ENSG00000118564 "F-box and leucine rich repeat protein 5" Q9UKA1 4 15604381-15681679 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 252.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 407.0" "Group enriched" "Detected in all" 5 "dendritic cells: 108.2;granulocytes: 407.0;monocytes: 225.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002484 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA002484: " "unprognostic (1.53e-1)" "unprognostic (8.08e-2)" "unprognostic (6.34e-3)" "unprognostic (1.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (2.18e-2)" "unprognostic (6.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.42e-2)" "unprognostic (3.70e-2)" "unprognostic (5.14e-2)" "prognostic favorable (6.18e-5)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (5.39e-3)" "unprognostic (6.18e-2)" 72.8 50.9 49.0 40.2 53.9 110.9 51.9 56.3 65.5 53.8 50.3 51.3 29.8 42.1 63.5 43.0 46.1 51.6 49.5 48.1 51.2 128.0 77.4 48.8 35.3 49.9 52.6 41.5 32.7 59.4 44.4 37.1 50.1 51.5 36.2 48.0 36.9 56.4 80.1 36.3 31.7 55.1 50.9 45.1 41.5 68.0 52.2 46.3 70.6 85.5 32.6 53.9 37.7 55.2 23.3 17.8 42.3 23.9 65.0 63.9 13.4 30.4 37.2 32.7 45.9 14.3 34.1 18.1 14.2 36.4 57.8 8.5 21.9 36.5 50.3 17.7 11.2 17.8 12.9 16.9 65.3 21.7 16.4 59.0 48.4 30.4 46.9 74.9 86.8 15.7 15.2 14.8 99.1 10.5 41.3 33.4 22.3 19.1 15.8 29.5 43.0 14.8 51.8 32.9 20.4 19.2 28.4 10.0 32.8 57.7 16.2 35.8 20.8 37.8 10.7 26.0 38.0 20.1 22.2 16.8 32.4 37.7 46.6 204.3 225.4 115.2 46.2 112.9 44.9 33.5 42.5 44.7 108.2 31.3 44.0 44.8 407.0 42.4 101.7 16.6 40.6 206.8 49.0 53.9 56.3 65.5 48.1 51.2 49.9 52.6 50.1 50.9 52.2 55.2 37.0 44.8 62.0 63.6 31.3 27.3 37.2 40.5 62.0 52.3 34.6 28.2 88.1 41.5 46.9 36.8 6.2 53.3 38.9 24.4 78.2 29.2 80.3 32.5 41.2 42.5 25.9 29.9 73.6 23.3 41.8 47.0 36.2 42.1 39.9 38.6 40.0 69.1 48.5 40.4 78.7 20.1 32.6 109.9 28.4 52.9 39.7 81.1 30.2 63.7 138.4 36.2 44.3 65.9 120.2 18.8 20.4 58.3 39.1 30.8 37.2 252.3 61.9 41.1 59.2 42.1 46.2 188.5 73.5 63.1 26.1 26.4 45.4 38.4 25.6 32.7 FBXO30 "Fbx30, MGC21674" ENSG00000118496 "F-box protein 30" Q8TB52 6 145793502-145814795 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 9.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012583 Approved Approved Microtubules NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 40: Granulosa cells - Unknown function" Microtubules "HPA012583: AB_2668686" "unprognostic (8.69e-2)" "unprognostic (3.35e-3)" "unprognostic (2.92e-2)" "unprognostic (4.29e-2)" "unprognostic (5.47e-3)" "unprognostic (8.36e-2)" "unprognostic (7.61e-7)" "unprognostic (5.79e-2)" "unprognostic (1.63e-1)" "unprognostic (6.32e-2)" "unprognostic (1.18e-2)" "unprognostic (9.25e-2)" "unprognostic (2.35e-1)" "unprognostic (3.28e-2)" "unprognostic (5.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.78e-1)" 4.5 4.0 3.8 4.2 5.0 7.2 4.0 4.6 3.9 4.1 2.7 9.7 4.1 6.7 3.1 9.6 3.2 5.6 7.2 3.1 6.0 4.1 3.4 3.2 4.3 4.5 5.5 5.9 3.8 4.0 1.6 4.8 4.7 6.0 4.7 5.3 4.4 6.8 11.5 2.6 3.5 8.0 4.2 3.7 3.7 6.5 5.1 2.9 8.0 9.1 4.1 5.7 2.9 5.3 3.7 6.9 9.7 13.2 9.9 8.8 9.9 10.3 9.6 6.9 6.8 8.7 3.3 17.0 7.8 11.8 12.6 5.7 8.4 7.5 10.4 10.0 5.8 10.8 9.1 8.8 17.8 14.1 10.8 14.6 8.3 8.6 11.4 9.0 10.1 4.1 12.6 11.9 13.6 2.9 6.4 7.5 11.2 2.4 5.1 8.2 21.7 5.9 7.2 3.8 4.3 6.9 12.6 6.5 6.1 9.6 3.0 13.8 13.4 7.1 6.0 9.1 10.4 8.8 7.2 6.8 11.4 6.0 7.7 9.3 1.3 1.6 0.4 1.1 0.3 0.6 0.4 0.8 1.6 1.3 0.6 0.6 1.2 0.5 0.9 0.5 0.3 0.6 3.8 5.0 4.6 3.9 3.1 6.0 4.5 5.5 4.7 4.2 5.1 5.3 11.1 3.2 5.9 7.2 5.4 14.3 5.3 4.2 12.5 8.8 10.5 8.3 22.9 10.0 4.7 3.7 4.2 5.8 5.7 4.9 11.7 4.7 10.9 4.1 13.7 13.8 6.0 36.7 5.3 3.2 3.4 15.4 7.1 6.2 12.0 37.1 11.4 9.7 7.5 26.9 6.4 5.0 2.0 11.9 20.8 4.4 11.1 10.2 7.2 7.5 7.5 12.0 0.0 5.0 7.6 5.1 3.2 10.1 11.1 7.1 4.3 8.2 2.8 8.7 0.0 26.5 18.4 19.7 10.5 12.4 17.3 5.6 6.2 7.2 5.0 5.0 FBXO36 "Fbx36, FLJ37592" ENSG00000153832 "F-box protein 36" Q8NEA4 2 229922302-230013119 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Early spermatids: 61.7;Endometrial ciliated cells: 40.8;Respiratory ciliated cells: 53.0;Spermatocytes: 55.8" "Cancer enhanced" "Detected in all" "testis cancer: 9.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053865 Approved Nucleoplasm,Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "HPA053865: AB_2682282" "unprognostic (4.39e-3)" "unprognostic (6.51e-2)" "unprognostic (2.38e-2)" "prognostic favorable (2.28e-4)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.15e-2)" "unprognostic (2.38e-2)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.28e-2)" "unprognostic (8.04e-2)" "unprognostic (7.79e-3)" "unprognostic (3.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.68e-1)" 1.9 3.7 4.6 0.7 4.2 0.8 3.5 4.3 4.5 3.0 3.9 1.2 1.4 2.5 2.8 1.6 11.0 1.7 1.2 3.7 4.4 5.1 1.6 2.3 0.9 5.8 5.6 2.4 1.6 4.3 2.7 1.6 5.1 2.9 1.2 9.0 2.3 2.5 0.8 3.0 1.4 1.7 5.4 0.8 1.7 6.0 4.4 1.5 7.4 0.8 1.0 1.3 1.5 5.1 1.0 1.9 2.3 0.9 1.1 6.8 4.6 1.2 3.2 1.7 2.9 0.7 3.1 0.1 0.6 2.2 2.1 0.8 1.1 0.6 2.9 0.3 0.7 0.4 0.6 1.2 4.4 0.8 0.3 7.2 5.2 3.2 2.4 2.2 1.8 3.4 1.4 0.6 2.0 4.2 1.7 1.9 6.1 2.2 2.2 2.0 0.6 0.5 3.0 0.8 2.2 2.8 2.0 1.6 0.8 2.6 3.4 1.4 1.3 2.8 1.0 4.6 0.5 2.1 1.8 0.7 3.4 0.4 2.1 0.0 0.5 0.0 0.8 0.4 0.6 1.1 0.6 0.6 1.3 0.7 1.4 0.8 0.2 1.0 0.3 0.6 1.2 0.5 4.6 4.2 4.3 4.5 3.7 4.4 5.8 5.6 5.1 5.4 4.4 5.1 3.1 9.6 1.1 11.4 1.1 3.8 2.9 8.3 1.2 8.3 4.3 4.3 3.7 0.0 9.9 11.0 35.5 1.9 0.6 2.3 15.6 6.2 61.7 40.8 4.9 2.3 0.0 2.5 19.5 6.6 2.0 3.7 3.1 4.7 0.0 4.2 1.4 2.7 1.1 10.1 22.1 1.6 14.2 1.6 3.0 10.5 3.4 1.2 3.6 5.6 2.9 7.5 4.1 12.5 12.5 6.2 0.5 4.1 0.7 3.0 2.2 12.2 53.0 28.8 6.6 2.8 4.2 55.8 8.6 3.2 4.5 2.2 1.5 9.1 1.4 1.9 FBXO8 "FBS, FBX8" ENSG00000164117 "F-box protein 8" Q9NRD0 4 174236658-174283667 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 80.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002885 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA002885: AB_1078835" "unprognostic (8.17e-2)" "unprognostic (6.59e-2)" "unprognostic (2.46e-1)" "unprognostic (3.18e-1)" "unprognostic (4.69e-2)" "unprognostic (2.04e-2)" "unprognostic (7.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.84e-2)" "unprognostic (3.72e-1)" "unprognostic (2.11e-2)" "unprognostic (2.25e-1)" "prognostic favorable (1.29e-7)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-1)" 15.7 18.6 13.8 10.5 15.3 10.2 17.8 15.7 17.5 14.3 13.8 18.4 16.3 12.5 19.9 17.0 15.5 15.5 21.2 13.5 16.6 22.9 47.5 14.0 12.9 15.8 14.7 17.0 14.2 21.2 14.2 30.9 16.1 14.7 16.1 17.8 15.2 12.6 6.7 16.1 16.4 16.3 15.1 13.0 15.0 11.2 14.8 15.8 22.2 10.1 12.6 16.0 13.7 17.8 10.0 6.3 12.3 4.3 31.5 33.2 9.8 18.8 19.2 13.3 13.6 5.2 19.9 6.9 19.5 15.7 12.2 6.7 9.2 11.7 13.8 22.5 20.9 7.2 10.4 7.4 23.5 8.5 7.5 19.1 24.5 12.9 13.4 20.5 13.4 8.0 14.9 40.5 18.3 7.9 9.8 8.6 4.4 15.4 7.6 4.9 8.2 12.5 17.8 4.1 13.9 80.8 8.7 16.1 22.4 11.8 11.0 11.0 17.0 9.1 7.3 23.5 11.3 18.5 9.7 6.2 25.2 6.4 13.0 29.4 6.5 14.0 12.1 8.4 15.2 13.2 13.7 12.1 9.0 11.9 12.7 11.6 6.6 10.5 10.0 9.1 16.6 8.4 13.8 15.3 15.7 17.5 13.5 16.6 15.8 14.7 16.1 15.1 14.8 17.8 18.9 3.2 10.0 6.5 15.8 20.6 17.0 26.0 19.4 13.2 16.9 11.4 10.8 15.7 19.5 22.0 6.2 36.6 10.1 20.3 50.9 19.0 20.5 24.9 13.2 15.8 12.1 11.2 10.1 10.9 60.6 32.7 14.8 16.3 2.5 5.3 21.0 58.1 21.2 18.5 13.0 21.5 28.5 19.6 8.2 5.5 17.4 12.2 10.6 11.2 16.3 29.1 9.2 9.0 17.8 12.4 21.4 26.4 9.1 16.8 21.5 44.6 26.2 18.1 13.1 14.9 18.4 34.7 17.6 19.8 31.4 89.6 14.3 10.3 13.7 22.7 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FCER1G ENSG00000158869 "Fc fragment of IgE receptor Ig" P30273 1 161215234-161220699 "FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgE-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.6;lymphoid tissue: 470.1" "Group enriched" "Detected in many" 9 "dendritic cells: 726.6;granulocytes: 705.6;Hofbauer cells: 2318.6;Kupffer cells: 1950.8;Langerhans cells: 1526.3;Macrophages: 1971.3;monocytes: 808.9;NK-cells: 1037.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 1987.3;classical monocyte: 3240.2;intermediate monocyte: 5333.6;myeloid DC: 2386.3;neutrophil: 1831.0;NK-cell: 1750.9;non-classical monocyte: 6984.5;plasmacytoid DC: 3315.6" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "HEL: 77.8;HMC-1: 301.7;THP-1: 276.1;U-266/84: 90.1;U-937: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022108, HPA026872" Supported NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "CAB022108: , HPA026872: AB_1848473" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.40e-2)" "unprognostic (8.73e-3)" "unprognostic (1.46e-1)" "unprognostic (4.28e-2)" "unprognostic (3.10e-3)" "unprognostic (1.84e-1)" "unprognostic (3.25e-1)" "unprognostic (9.63e-2)" "unprognostic (2.28e-2)" "unprognostic (5.67e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.99e-1)" "unprognostic (6.28e-2)" "unprognostic (2.04e-2)" "unprognostic (7.87e-2)" 251.7 86.5 34.0 275.6 33.8 441.6 62.9 35.5 66.0 52.5 47.5 82.7 44.9 30.7 38.7 30.6 72.0 101.5 53.1 33.7 42.0 40.3 177.3 286.6 160.9 53.4 48.7 19.9 22.3 26.8 26.9 211.0 50.1 31.0 113.2 8.3 42.9 38.8 11.9 21.0 60.6 160.3 41.5 470.1 39.4 14.5 49.9 62.7 25.5 34.6 82.5 254.6 21.7 65.4 0.2 0.0 0.7 1.3 1.8 0.7 0.4 0.5 0.2 0.5 0.8 2.2 0.1 0.5 0.7 0.0 0.3 0.2 0.5 0.0 0.4 0.3 1.5 77.8 0.6 14.0 0.3 16.1 301.7 6.0 3.3 2.3 0.2 0.7 0.4 1.8 0.1 7.3 2.4 0.5 1.4 37.9 1.6 0.0 0.0 0.1 6.7 0.2 0.5 0.4 0.3 1.0 0.6 0.1 2.7 1.4 0.2 276.1 0.4 1.8 0.4 0.9 1.1 3.0 90.1 0.9 1.7 87.1 0.5 1987.3 3240.2 307.3 13.6 5333.6 15.9 28.2 10.6 10.6 2386.3 9.0 17.3 45.0 1831.0 1750.9 6984.5 3315.6 21.8 4265.5 34.0 33.8 35.5 66.0 33.7 42.0 53.4 48.7 50.1 41.5 49.9 65.4 12.8 86.6 147.7 0.7 35.9 39.6 1.5 0.2 1.8 0.1 5.2 22.1 6.8 15.7 27.3 18.4 0.0 14.5 726.6 1.0 0.0 1.9 3.0 1.0 0.9 38.6 1.8 79.3 0.1 1.0 18.8 18.3 1.1 1.0 705.6 0.5 41.0 13.6 2318.6 0.0 0.2 0.5 0.0 1950.8 1526.3 9.4 5.3 1971.3 80.0 12.2 808.9 0.2 1037.1 0.0 0.1 1.0 1.4 1.2 10.1 1.3 0.4 5.4 15.3 2.3 72.3 3.8 11.2 1.0 2.5 1.4 35.9 23.7 133.3 0.4 0.6 1.8 FCF1 "Bka, C14orf111, CGI-35, UTP24" ENSG00000119616 "FCF1 rRNA-processing protein" Q9Y324 14 74713144-74738620 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.7;Smooth muscle cells: 67.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA046681 Approved Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA046681: AB_10960541" "unprognostic (1.39e-2)" "unprognostic (1.54e-1)" "unprognostic (5.74e-2)" "unprognostic (1.01e-2)" "unprognostic (1.18e-1)" "unprognostic (7.94e-3)" "prognostic unfavorable (5.54e-6)" "unprognostic (3.17e-1)" "unprognostic (3.43e-2)" "unprognostic (7.36e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (7.79e-2)" "prognostic favorable (2.26e-4)" "unprognostic (3.30e-1)" "unprognostic (1.46e-1)" "unprognostic (3.03e-1)" "unprognostic (1.47e-1)" 32.5 23.1 9.9 25.4 12.7 27.0 34.9 12.7 13.0 30.5 11.5 28.6 18.9 29.2 20.9 24.9 38.4 22.0 26.8 9.4 12.1 30.1 32.8 27.9 34.4 12.5 12.7 39.9 16.5 26.6 12.9 32.1 12.8 28.2 29.3 13.2 19.9 30.6 25.3 17.3 20.5 30.2 11.3 23.5 23.0 18.4 11.4 33.2 43.3 22.4 41.3 29.2 19.0 17.4 109.3 78.7 55.8 63.5 86.8 76.3 73.5 93.6 71.7 91.4 81.2 88.1 87.3 97.2 59.6 82.1 44.2 78.5 94.1 88.5 160.7 90.6 40.8 67.4 46.4 57.9 62.6 83.1 59.5 60.3 76.6 97.3 101.4 72.4 86.6 82.7 82.2 56.9 83.3 77.5 97.0 29.6 75.0 63.2 90.5 72.9 109.5 46.3 46.4 88.1 39.1 56.9 120.1 62.8 55.0 61.4 80.7 57.0 79.9 72.7 77.6 69.5 108.3 49.9 140.7 147.7 69.2 77.5 82.5 13.5 17.0 20.5 19.1 15.3 21.0 24.3 18.4 16.6 13.9 21.2 19.5 20.5 14.7 15.3 18.8 31.3 19.6 9.2 9.9 12.7 12.7 13.0 9.4 12.1 12.5 12.7 12.8 11.3 11.4 17.4 11.9 6.4 18.3 7.5 18.8 3.1 7.6 10.5 11.4 7.5 12.2 7.5 24.0 34.3 14.9 12.9 6.2 11.8 26.6 16.3 15.6 17.4 23.8 28.0 18.5 13.7 10.2 36.2 11.6 19.0 14.7 13.3 6.1 13.5 26.0 9.3 28.5 104.7 12.8 11.8 11.7 15.9 8.2 33.6 4.3 11.9 15.5 12.6 0.0 7.5 16.4 13.5 24.7 11.6 17.5 17.4 10.3 17.0 12.0 6.1 13.1 18.4 45.4 7.2 13.1 12.5 67.7 12.4 12.3 11.1 4.8 8.8 14.3 8.2 15.6 6.7 FCGR3A "CD16, CD16a, FCG3, FCGR3" ENSG00000203747 "Fc fragment of IgG receptor IIIa" P08637 1 161541759-161550737 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 206.3;lymphoid tissue: 306.8" "Cell type enhanced" "Detected in many" "dendritic cells: 333.4;Hofbauer cells: 193.1;Kupffer cells: 807.9;Macrophages: 300.0;NK-cells: 579.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "intermediate monocyte: 1763.5;neutrophil: 1169.8;non-classical monocyte: 3948.7" "Group enriched" "Detected in all" 5 "granulocytes: 1169.8;monocytes: 3948.7" "Not detected" "Not detected" "CAB032435, HPA055431" Supported "Secreted to blood" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB032435: AB_626925, HPA055431: AB_2682815" "unprognostic (5.27e-2)" "unprognostic (9.95e-2)" "unprognostic (2.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (2.24e-2)" "unprognostic (6.06e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.98e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-6)" "unprognostic (1.14e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" "unprognostic (7.51e-2)" 52.9 41.9 18.4 99.8 20.4 27.3 14.7 19.3 27.2 8.2 26.5 12.5 5.8 5.9 5.9 4.9 9.1 24.5 22.3 16.9 22.0 7.9 111.5 206.3 37.1 37.7 27.9 6.6 7.8 13.6 11.3 71.0 30.6 6.9 12.6 6.9 14.7 7.6 3.3 2.2 5.7 68.4 31.7 306.8 6.8 7.7 28.8 9.3 7.0 4.3 3.9 32.5 3.5 39.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.5 26.2 9.6 513.6 1763.5 4.9 3.7 4.7 205.9 175.8 1.4 3.0 184.0 1169.8 136.2 3948.7 4.6 2.6 734.1 18.4 20.4 19.3 27.2 16.9 22.0 37.7 27.9 30.6 31.7 28.8 39.8 2.7 22.4 24.6 0.7 6.5 0.5 0.1 0.0 0.0 0.2 1.4 3.4 0.7 8.6 10.5 3.7 2.1 1.2 333.4 0.0 0.0 0.2 1.4 0.1 0.0 18.9 0.0 16.4 0.0 0.0 1.4 3.9 0.0 0.1 18.9 0.1 8.6 5.3 193.1 0.0 0.1 0.1 0.0 807.9 7.4 3.7 0.3 300.0 0.0 20.6 77.2 0.1 579.9 0.0 0.1 0.0 0.0 0.0 22.1 0.0 0.0 0.8 5.8 1.5 19.7 1.1 0.4 0.0 0.5 0.2 0.0 2.1 88.0 0.0 0.0 0.3 FCGR3B "CD16, CD16b, FCG3, FCGR3" ENSG00000162747 "Fc fragment of IgG receptor IIIb" O75015 1 161623196-161631963 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.6;lymphoid tissue: 82.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Club cells: 3.1;dendritic cells: 2.2;Fibroblasts: 2.2;Kupffer cells: 2.2;Macrophages: 4.3;NK-cells: 2.1;Respiratory ciliated cells: 2.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.7" "Immune cell enriched" "Detected in many" 79 "neutrophil: 7208.7" "Lineage enriched" "Detected in many" 79 "granulocytes: 7208.7" "Not detected" "Not detected" "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.60e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-3)" "unprognostic (4.16e-2)" "unprognostic (1.15e-1)" "unprognostic (6.52e-2)" "unprognostic (3.97e-2)" "unprognostic (6.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (8.67e-2)" "unprognostic (5.16e-2)" "unprognostic (1.35e-1)" "unprognostic (8.37e-3)" "unprognostic (2.28e-1)" "unprognostic (9.24e-2)" 23.0 2.8 0.6 76.4 1.2 36.6 1.3 0.7 6.7 2.8 1.1 2.1 0.5 0.9 0.0 5.0 5.2 16.4 3.5 0.6 0.7 1.9 7.9 22.0 1.3 1.0 0.8 0.4 4.0 1.4 0.7 9.1 2.7 0.8 0.9 0.0 1.3 0.4 0.8 4.0 2.4 5.6 0.7 82.0 1.8 0.2 1.1 6.1 1.3 23.0 1.5 18.3 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.1 12.5 17.2 30.4 0.6 0.3 0.9 6.9 3.0 0.6 0.5 6.2 7208.7 3.6 90.8 0.4 0.6 18.5 0.6 1.2 0.7 6.7 0.6 0.7 1.0 0.8 2.7 0.7 1.1 1.1 0.0 3.2 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 1.5 3.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.3 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 2.2 0.0 0.9 0.0 4.3 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.0 FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 313.7" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1139.6;Theca cells: 745.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 71.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Mitochondria "HPA041630: AB_10793970, HPA062087: AB_2630366" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (5.29e-3)" "unprognostic (4.67e-2)" "unprognostic (2.39e-1)" "unprognostic (4.32e-3)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.10e-2)" "unprognostic (5.48e-2)" "prognostic favorable (3.58e-7)" "prognostic favorable (2.53e-4)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" "unprognostic (2.80e-1)" 9.0 313.7 6.9 6.8 7.5 12.1 8.5 7.5 8.6 7.4 8.7 12.9 22.0 6.2 8.2 9.3 5.9 9.1 16.3 6.8 7.6 29.6 44.3 10.8 7.9 7.3 7.8 5.4 13.4 9.3 6.1 17.7 7.6 8.2 10.7 5.3 8.6 26.3 20.6 6.2 18.4 6.1 7.5 6.7 13.5 7.6 7.9 12.0 20.3 18.5 7.5 10.5 5.5 8.8 10.2 7.0 10.6 11.6 10.1 17.8 23.5 9.2 11.2 8.0 13.5 24.1 16.7 23.8 26.4 11.9 14.2 11.8 12.4 13.9 10.8 22.9 15.8 12.0 12.0 14.8 17.7 12.7 18.8 31.3 11.4 7.3 17.1 13.8 16.5 16.2 12.2 34.4 17.3 11.3 18.2 28.3 9.5 19.3 13.1 26.4 10.1 22.1 17.4 18.1 14.4 7.4 17.5 19.7 12.5 12.3 11.7 8.7 9.8 8.0 9.8 9.8 9.9 7.7 6.4 71.7 6.0 25.5 10.5 1.8 4.5 2.8 3.8 3.3 4.1 9.7 5.2 5.4 5.2 7.5 6.2 4.4 0.5 3.4 4.6 4.0 7.4 2.6 6.9 7.5 7.5 8.6 6.8 7.6 7.3 7.8 7.6 7.5 7.9 8.8 53.2 19.2 38.1 15.0 68.6 68.3 104.3 45.4 42.7 33.0 40.3 37.0 57.1 102.9 28.3 80.9 8.4 174.3 65.7 109.5 244.6 71.4 53.4 49.6 35.6 36.7 47.9 28.8 22.6 144.8 169.4 48.1 61.2 42.0 45.7 36.3 45.0 192.7 113.3 42.1 25.8 56.2 34.6 58.4 68.3 11.0 46.9 77.3 69.4 15.0 57.3 42.3 50.4 22.1 19.6 78.5 76.5 45.5 102.7 114.2 183.9 338.7 18.6 17.3 26.3 50.6 43.6 48.0 67.0 75.3 97.5 1139.6 74.0 745.1 96.4 149.6 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 892.7;tongue: 925.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 759.3;ASC TERT1: 468.5;HHSteC: 593.0;HSkMC: 718.3;hTCEpi: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Enhanced Nucleoplasm No No 39000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB009315: AB_2278350, HPA031092: AB_10600195, HPA031093: AB_10601748, HPA031095: AB_2673734" "unprognostic (2.09e-3)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.72e-1)" "unprognostic (6.30e-3)" "unprognostic (3.70e-3)" "unprognostic (1.47e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (7.48e-3)" "unprognostic (2.18e-3)" "unprognostic (8.31e-2)" "unprognostic (4.22e-2)" "unprognostic (6.90e-3)" 400.1 92.3 18.2 70.1 26.8 26.6 160.4 19.7 32.1 86.4 20.2 110.9 11.3 97.5 63.0 130.6 104.6 78.9 93.7 16.8 20.7 108.8 144.5 92.7 166.7 22.7 23.8 122.1 200.4 227.0 52.9 28.5 23.5 85.0 37.1 25.6 61.0 49.8 892.7 114.0 135.7 81.8 17.0 105.6 129.0 41.4 22.1 229.4 97.2 925.1 80.3 108.9 109.1 26.2 40.0 17.1 73.1 109.7 759.3 468.5 1.2 21.2 1.0 13.6 31.0 29.7 6.9 195.3 19.5 4.1 11.8 0.6 44.1 93.2 32.0 77.7 41.6 84.0 14.1 41.7 593.0 53.3 8.3 718.3 368.6 23.7 220.5 14.8 80.1 38.8 91.3 77.1 144.3 25.3 222.5 99.6 18.9 8.7 12.3 97.7 19.1 95.4 60.2 23.7 27.7 16.8 17.3 19.8 4.2 15.9 108.4 62.2 178.7 19.3 17.3 2.8 29.7 34.9 42.9 243.5 6.6 102.3 7.6 57.6 105.0 70.0 64.4 92.3 78.0 9.7 90.6 68.5 107.5 12.5 133.4 96.7 85.1 45.2 46.8 32.0 37.2 158.5 18.2 26.8 19.7 32.1 16.8 20.7 22.7 23.8 23.5 17.0 22.1 26.2 180.2 12.8 11.3 23.2 42.9 17.6 59.2 20.1 37.0 1.9 32.0 20.8 131.8 74.4 14.2 5.5 0.0 1.2 102.0 14.3 23.5 0.6 9.8 55.7 76.1 57.9 20.9 102.2 25.9 7.9 0.8 97.5 18.8 79.2 38.5 54.7 117.1 225.6 35.1 0.0 2.8 35.5 34.6 384.2 44.8 22.0 160.9 192.2 7.2 66.5 110.3 4.6 44.3 16.6 26.3 2.9 19.3 218.6 66.4 49.9 157.0 27.4 18.2 22.6 144.7 188.1 106.8 14.9 19.1 37.5 21.3 0.4 128.7 2.8 39.5 22.2 FOLR2 FRβ ENSG00000165457 "Folate receptor beta" P14207 11 72216601-72221950 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Transport Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 168.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 1114.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 64.2;intermediate monocyte: 50.6" "Group enriched" "Detected in many" 4 "dendritic cells: 18.7;monocytes: 64.2" "Cell line enriched" "Detected in some" 5 "U-698: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 15000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (2.03e-1)" "unprognostic (6.58e-3)" "prognostic unfavorable (8.42e-4)" "unprognostic (1.47e-1)" "unprognostic (2.76e-1)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-1)" "unprognostic (2.51e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-1)" "unprognostic (3.91e-3)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.98e-3)" 119.1 55.0 10.7 28.2 11.0 10.8 31.7 8.2 18.6 27.9 13.8 36.0 19.5 13.5 12.4 31.6 16.8 80.1 38.6 10.9 9.5 10.8 44.8 39.7 78.5 9.3 10.7 16.0 7.1 7.9 6.1 168.4 11.4 6.1 46.7 0.2 12.8 16.7 5.9 9.8 29.6 46.3 9.3 27.7 21.0 13.0 16.2 28.7 9.1 26.3 29.0 81.3 6.3 16.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.2 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.0 0.2 0.0 18.6 0.5 0.8 0.0 0.0 64.2 0.0 0.3 50.6 0.0 9.5 0.0 0.0 18.7 4.0 0.0 0.0 1.1 1.8 13.7 0.2 0.0 20.4 10.7 11.0 8.2 18.6 10.9 9.5 9.3 10.7 11.4 9.3 16.2 16.1 3.4 0.0 0.6 0.0 8.0 7.9 0.1 0.0 1.2 0.0 0.1 1.1 2.2 1.5 0.0 0.0 0.0 7.6 0.6 0.0 0.0 0.0 0.9 0.3 0.1 2.3 0.0 0.0 0.0 0.0 6.0 2.4 0.0 0.5 2.5 0.0 2.2 1.7 1114.8 0.0 0.0 0.0 0.0 229.3 98.8 2.5 1.5 199.4 0.0 15.9 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 2.1 0.1 0.0 0.2 0.0 0.3 0.0 2.5 1.2 0.6 0.7 1.3 5.1 16.0 1.2 0.1 0.0 0.1 FREM2 DKFZp686J0811 ENSG00000150893 "FRAS1 related extracellular matrix 2" Q5SZK8 13 38687077-38887131 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 7.7;thyroid gland: 4.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 27.2;Astrocytes: 46.0;Cholangiocytes: 15.7;Endometrial ciliated cells: 18.6;Glandular and luminal cells: 48.6;Oligodendrocyte precursor cells: 15.6;Proximal tubular cells: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 10.6;MCF7: 7.8;RT4: 7.2;SK-BR-3: 6.3;SuSa: 29.7;WM-115: 5.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA028831 Uncertain Approved Cytosol NA NA 1500000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Cytosol "HPA028831: AB_10603668" "unprognostic (1.71e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-1)" "unprognostic (4.69e-1)" "unprognostic (6.24e-2)" "unprognostic (1.62e-1)" "unprognostic (8.42e-3)" "unprognostic (8.54e-2)" "unprognostic (1.64e-3)" "unprognostic (4.25e-1)" "unprognostic (2.54e-1)" "prognostic favorable (2.23e-7)" "unprognostic (7.21e-2)" "unprognostic (1.40e-1)" "unprognostic (9.92e-2)" "unprognostic (3.14e-1)" 0.2 0.1 0.3 0.0 1.1 0.0 0.2 0.2 0.9 0.3 0.1 0.5 0.1 0.5 0.2 0.0 0.4 0.8 0.0 0.6 0.0 7.7 2.0 2.2 0.0 0.0 0.4 0.7 2.7 0.0 0.3 1.4 0.0 1.8 0.1 0.3 0.0 0.7 2.8 0.1 0.2 0.3 0.0 0.1 0.9 0.3 0.0 0.2 4.9 3.6 0.0 0.2 0.0 0.0 0.0 0.0 15.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 10.6 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 2.3 0.0 0.2 0.0 1.4 0.1 2.3 7.2 0.2 0.1 0.0 6.3 0.3 29.7 1.1 0.0 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 0.2 0.9 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 27.2 46.0 0.0 0.6 0.1 0.7 0.0 0.2 0.4 0.5 2.7 15.7 1.4 1.8 0.0 5.9 0.0 0.3 5.9 3.2 0.5 18.6 4.5 0.6 0.0 0.0 0.5 0.2 0.4 0.4 0.0 48.6 0.0 0.5 0.0 1.3 0.8 0.0 9.1 0.1 2.0 0.3 0.0 0.1 0.0 0.2 0.0 3.7 0.0 3.3 0.0 15.6 9.7 1.0 0.1 0.0 0.0 0.0 0.0 24.8 2.9 0.3 0.0 3.1 0.7 0.2 0.9 0.0 0.1 1.9 0.5 2.9 0.1 0.1 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUCA2 "dJ20N2.5, MGC1314" ENSG00000001036 "Alpha-L-fucosidase 2" Q9BTY2 6 143494812-143511720 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 165.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031659, HPA031661" Approved "Secreted to blood" NA NA 56000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA031659: AB_10600661, HPA031661: AB_10601681" "unprognostic (1.83e-2)" "unprognostic (1.70e-3)" "unprognostic (1.11e-2)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (2.70e-9)" "unprognostic (1.54e-3)" "unprognostic (1.08e-1)" "unprognostic (7.79e-2)" "unprognostic (2.89e-1)" "unprognostic (1.90e-1)" "unprognostic (8.76e-3)" "unprognostic (9.18e-2)" "unprognostic (2.69e-1)" "unprognostic (7.25e-2)" "unprognostic (5.07e-2)" 28.9 41.4 13.5 25.4 16.4 25.8 26.3 16.0 15.3 29.2 30.2 41.5 42.6 25.6 44.9 14.2 23.7 27.8 27.9 12.4 16.5 54.8 52.3 28.9 17.2 17.1 14.2 30.4 34.6 165.8 15.8 50.5 17.8 21.9 52.8 6.1 25.4 25.8 6.9 12.3 39.3 27.6 16.4 24.6 38.3 12.6 15.9 6.6 32.0 11.6 17.0 33.5 20.4 20.9 97.4 55.7 47.6 86.9 69.0 134.4 90.1 89.9 95.4 108.1 182.0 107.1 94.8 0.2 66.1 120.8 33.9 0.6 24.1 11.7 148.9 87.2 92.6 32.6 100.1 163.2 99.3 0.3 15.8 72.3 69.4 96.6 41.5 91.6 111.4 0.2 117.6 49.3 123.2 114.6 0.2 75.9 62.1 44.2 76.0 0.2 99.7 72.1 129.0 59.5 36.0 23.6 98.7 65.3 82.3 36.3 32.1 79.6 65.9 64.1 54.0 161.6 175.4 18.3 21.3 0.7 74.1 59.1 22.5 38.8 84.9 26.2 13.2 84.0 15.0 11.3 9.8 11.3 65.4 8.3 4.4 7.9 5.5 29.6 62.0 10.3 19.8 51.9 13.5 16.4 16.0 15.3 12.4 16.5 17.1 14.2 17.8 16.4 15.9 20.9 27.3 41.7 35.9 9.1 13.5 11.2 12.6 30.3 9.1 3.7 19.2 12.6 28.0 38.6 37.9 25.8 0.0 52.5 10.3 47.6 11.7 81.9 2.0 26.8 55.2 25.0 9.6 18.7 8.7 124.9 109.8 62.6 34.7 28.9 37.4 38.1 23.6 35.2 110.3 1.7 11.8 38.1 46.8 57.5 29.2 2.6 66.8 51.7 42.7 9.4 49.1 11.1 13.4 5.5 14.5 74.6 38.2 45.5 47.7 13.8 60.3 51.4 34.8 1.1 6.6 33.8 35.0 4.8 4.6 13.2 8.0 46.4 11.5 78.8 50.4 18.4 FUNDC1 MGC51029 ENSG00000069509 "FUN14 domain containing 1" Q8IVP5 X 44523639-44542859 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038773 Uncertain NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA038773: AB_10670789" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.91e-1)" "unprognostic (3.11e-2)" "unprognostic (4.93e-1)" "unprognostic (1.72e-2)" "unprognostic (3.40e-3)" "unprognostic (1.88e-3)" "unprognostic (6.40e-2)" "unprognostic (2.85e-3)" "unprognostic (6.63e-2)" "unprognostic (1.30e-1)" "unprognostic (4.08e-1)" "unprognostic (2.49e-2)" "prognostic favorable (8.35e-4)" "unprognostic (6.67e-3)" "prognostic favorable (2.58e-4)" 11.5 18.4 30.5 9.5 31.3 11.3 20.4 35.9 37.8 14.4 30.3 12.7 12.5 13.4 22.4 13.1 15.3 15.8 37.6 30.5 34.2 25.2 13.0 10.5 17.8 36.0 31.7 19.0 10.2 28.2 14.8 11.5 34.5 16.3 13.5 34.2 49.2 11.5 17.9 16.2 8.0 12.4 32.0 12.8 29.7 14.4 33.3 20.0 16.8 24.9 16.3 15.5 12.0 32.1 39.4 33.1 36.5 22.4 15.8 21.8 20.8 19.4 29.4 38.2 41.7 41.3 32.2 29.0 19.1 26.6 83.5 21.0 60.4 36.7 46.2 32.2 67.6 32.5 41.5 32.3 23.4 35.3 103.3 22.1 35.3 55.1 27.4 36.6 23.8 30.9 34.9 18.0 45.8 41.6 32.9 42.6 43.3 33.6 38.4 20.3 37.1 21.5 39.1 28.0 20.0 31.6 59.3 32.5 37.7 66.0 65.4 0.1 14.0 23.5 34.1 28.0 21.6 14.0 25.2 34.6 31.1 13.8 31.3 7.5 6.3 10.9 7.3 6.3 9.8 10.8 10.1 11.5 11.6 6.6 11.5 9.0 6.8 11.5 4.6 23.8 10.7 5.5 30.5 31.3 35.9 37.8 30.5 34.2 36.0 31.7 34.5 32.0 33.3 32.1 15.2 19.2 10.8 5.2 12.5 14.8 20.1 67.3 18.2 21.9 18.6 21.2 41.6 27.1 34.1 25.8 6.2 35.3 13.0 14.0 115.4 33.6 1.7 27.1 20.9 15.8 10.2 12.0 5.3 36.8 29.4 20.2 16.8 23.1 7.6 36.4 20.3 14.8 37.5 21.9 6.4 13.8 42.7 14.5 7.2 5.7 23.0 13.6 14.2 6.5 13.1 62.9 17.5 6.6 6.8 34.6 26.0 21.8 14.3 17.5 14.5 50.7 26.4 16.1 13.1 12.9 19.8 19.9 45.4 20.7 16.3 26.5 12.7 35.5 17.1 26.0 FXN "CyaY, FA, FARR, FRDA, X25" ENSG00000165060 Frataxin Q16595 9 69035751-69079076 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022164, HPA068304" Supported Supported Mitochondria,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria Cytosol "CAB022164: , HPA068304: AB_2685970" "unprognostic (3.38e-2)" "unprognostic (1.54e-1)" "unprognostic (7.47e-2)" "unprognostic (2.37e-3)" "unprognostic (4.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (4.19e-2)" "unprognostic (2.53e-1)" "unprognostic (2.71e-3)" "unprognostic (1.10e-1)" "unprognostic (9.06e-2)" "unprognostic (1.67e-1)" "unprognostic (4.74e-2)" 10.3 20.1 8.9 7.8 9.2 29.1 10.1 9.7 8.9 9.3 11.7 10.4 7.4 12.1 12.1 9.5 10.2 5.3 27.0 9.0 10.4 12.9 46.3 7.1 9.8 9.8 10.2 17.6 15.1 22.2 8.1 9.1 9.8 10.2 12.3 4.1 11.7 13.6 25.5 5.2 7.7 13.3 9.5 12.6 10.1 10.7 9.9 5.4 10.4 19.8 10.4 12.3 7.9 10.4 27.0 22.1 34.2 17.0 15.7 23.1 34.3 18.6 16.3 28.0 21.2 11.8 16.6 45.9 14.0 19.5 28.8 28.6 41.8 42.6 34.9 53.9 47.5 66.2 14.1 87.2 26.7 48.7 27.7 25.7 33.7 27.8 29.9 9.6 37.7 28.0 50.3 43.9 26.1 25.6 14.0 21.0 47.5 53.1 42.8 32.7 24.0 32.0 32.2 21.5 26.9 12.1 19.2 12.5 20.7 24.3 14.1 14.4 22.7 18.0 32.0 24.1 27.6 11.6 11.4 27.8 8.5 39.7 18.5 8.1 39.9 0.4 48.6 45.4 37.5 36.3 48.0 48.4 42.8 22.7 61.6 59.8 1.9 60.8 36.2 33.2 43.3 49.5 8.9 9.2 9.7 8.9 9.0 10.4 9.8 10.2 9.8 9.5 9.9 10.4 11.0 3.2 11.5 13.1 19.9 9.7 19.8 36.6 14.8 6.8 16.9 20.8 38.2 10.0 10.5 14.7 4.2 39.9 14.9 4.9 21.5 17.5 2.4 11.7 22.5 16.9 7.2 56.1 14.2 14.7 22.3 14.7 14.3 8.7 7.0 15.4 11.0 69.0 33.4 0.0 18.6 15.3 18.3 22.1 16.1 6.3 15.8 13.9 17.8 9.4 18.3 7.6 28.8 6.6 10.8 15.0 3.7 13.2 42.0 17.1 5.8 27.2 7.4 1.6 13.1 10.1 19.8 5.1 32.3 29.8 8.1 14.6 17.1 27.9 17.5 14.1 G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070735-44076344 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "HPA067052: AB_2685771" "unprognostic (9.13e-2)" "unprognostic (2.28e-1)" "unprognostic (3.61e-1)" "prognostic favorable (1.11e-4)" "unprognostic (1.88e-3)" "unprognostic (3.16e-1)" "prognostic unfavorable (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (2.43e-1)" "unprognostic (1.15e-2)" "unprognostic (2.59e-2)" "unprognostic (1.85e-3)" "unprognostic (1.87e-3)" "unprognostic (4.53e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-1)" "unprognostic (4.49e-2)" 56.7 97.2 64.8 22.5 67.8 16.0 55.6 70.5 79.3 47.6 88.8 42.1 28.7 55.4 63.9 37.1 45.6 23.9 61.9 65.3 77.5 75.2 26.4 42.9 19.3 74.9 86.9 44.3 56.5 66.7 95.1 25.8 96.1 59.5 18.2 17.1 48.7 40.6 54.3 26.8 39.6 23.0 67.9 45.2 51.4 55.1 72.7 15.2 71.1 26.4 12.0 48.7 37.7 72.4 40.0 231.7 73.7 128.5 77.9 58.3 55.3 45.0 86.9 96.2 64.4 97.1 62.3 88.9 62.8 95.1 65.4 67.4 53.5 92.1 44.5 46.4 86.0 49.3 142.5 182.4 84.1 46.1 59.8 77.3 44.3 93.1 62.3 59.6 79.3 35.9 51.5 109.6 72.5 112.1 22.4 71.4 99.3 48.7 133.5 45.6 48.4 207.5 137.6 93.6 92.7 83.0 49.1 57.4 59.3 82.9 158.6 45.1 87.6 98.8 53.1 26.8 63.5 74.0 56.2 26.1 110.3 38.2 128.9 3.0 33.1 7.9 9.9 43.4 12.1 12.1 8.0 9.1 54.2 13.9 9.7 12.9 1.4 17.5 26.3 74.5 8.5 16.9 64.8 67.8 70.5 79.3 65.3 77.5 74.9 86.9 96.1 67.9 72.7 72.4 22.3 3.2 12.9 5.2 10.4 2.5 17.3 31.8 8.0 10.5 20.7 21.5 6.4 21.5 25.2 40.5 12.5 64.3 17.1 12.4 13.7 59.3 5.0 18.9 22.1 26.0 22.9 9.7 2.8 49.4 41.1 25.0 16.8 20.1 18.3 20.2 18.5 7.1 58.7 5.0 4.5 14.1 24.4 21.6 12.2 6.2 20.2 20.9 14.2 0.0 21.8 30.7 10.3 8.0 5.5 33.6 13.6 23.0 27.2 19.5 20.5 36.0 24.6 8.3 13.1 15.3 21.4 31.5 26.7 14.3 2.6 42.5 7.0 43.9 19.7 17.2 GABARAP "ATG8A, MM46" ENSG00000170296 "GABA type A receptor-associated protein" O95166 17 7240008-7242449 "Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 498.6;Ductal cells: 462.5;Plasma cells: 482.6;Squamous epithelial cells: 457.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065883 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Vesicles "HPA065883: AB_2685574" "unprognostic (2.58e-1)" "unprognostic (4.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.08e-2)" "unprognostic (1.19e-1)" "unprognostic (4.30e-2)" "unprognostic (1.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "prognostic favorable (9.52e-5)" "unprognostic (1.85e-1)" "unprognostic (1.45e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.22e-2)" "unprognostic (1.58e-1)" 609.8 848.2 777.0 344.7 799.2 478.8 610.9 826.8 1091.7 696.5 776.2 600.1 292.4 548.9 574.9 479.4 561.2 302.8 740.4 753.9 807.5 741.1 625.2 569.8 308.5 819.2 790.0 751.1 732.2 662.1 851.7 302.2 829.3 604.6 372.4 280.6 592.3 385.4 1001.1 662.8 496.8 341.4 817.6 651.6 658.9 604.5 803.0 389.2 552.3 916.4 411.0 534.0 547.5 862.7 233.5 342.1 598.0 404.5 887.1 999.5 227.0 377.1 645.5 330.1 491.2 141.9 200.6 233.9 233.2 672.0 430.6 206.9 428.1 329.7 441.7 421.8 474.4 182.8 301.3 377.3 858.3 118.7 369.6 1016.1 445.4 424.5 378.9 925.6 623.7 350.0 143.6 256.8 577.5 159.4 288.4 267.6 242.0 420.9 329.1 393.8 273.3 318.8 682.9 240.9 262.8 695.8 284.1 262.5 409.4 439.3 333.4 228.4 563.7 363.6 211.1 357.7 314.8 280.6 294.2 152.6 586.1 296.2 383.5 2968.2 4092.7 3746.6 766.9 3665.8 796.1 1262.2 906.3 810.4 3152.3 1156.6 812.9 765.5 7095.7 734.6 3213.5 2410.2 1132.5 4745.4 777.0 799.2 826.8 1091.7 753.9 807.5 819.2 790.0 829.3 817.6 803.0 862.7 24.0 89.8 120.1 44.4 183.6 20.8 3.9 21.3 498.6 2.4 64.1 31.9 0.5 54.3 81.3 27.6 0.0 24.3 35.8 302.0 43.0 462.5 24.1 25.5 32.4 61.5 396.5 179.3 36.7 309.6 31.1 124.2 264.6 24.8 150.0 6.9 45.0 39.9 78.2 1.7 37.7 314.3 34.6 147.0 60.8 71.3 21.1 397.4 33.8 43.1 399.2 15.1 32.0 21.1 87.8 375.2 374.3 13.9 482.6 6.0 384.7 72.0 166.4 3.0 6.6 5.2 74.2 22.1 5.8 457.2 23.2 52.9 105.2 5.2 237.1 4.9 GAL3ST3 GAL3ST2 ENSG00000175229 "Galactose-3-O-sulfotransferase 3" Q96A11 11 66040765-66049161 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.7;thyroid gland: 17.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.9;Cardiomyocytes: 3.6;Cone photoreceptor cells: 10.4;Excitatory neurons: 3.7;Horizontal cells: 5.0;Inhibitory neurons: 4.7;Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 15.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;ovarian cancer: 5.5;thyroid cancer: 10.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "NTERA-2: 6.5;SH-SY5Y: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "prognostic unfavorable (6.53e-6)" "unprognostic (1.24e-1)" "unprognostic (3.30e-1)" "unprognostic (1.57e-2)" "unprognostic (2.62e-1)" "unprognostic (6.08e-2)" "unprognostic (2.01e-3)" "unprognostic (7.26e-2)" "unprognostic (2.07e-2)" "unprognostic (1.40e-1)" "unprognostic (5.29e-1)" 0.0 0.0 5.3 0.0 7.7 0.0 0.0 4.8 5.7 2.9 0.1 0.0 0.0 3.9 0.1 0.0 2.6 0.0 7.1 4.8 2.1 5.3 0.0 0.0 0.0 2.0 2.6 0.2 0.6 0.3 4.1 0.0 1.6 0.8 0.0 5.7 0.0 1.6 0.3 0.1 0.0 2.8 1.5 0.0 0.0 2.1 2.8 0.0 17.1 0.3 0.0 0.0 0.3 3.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.7 4.8 5.7 4.8 2.1 2.0 2.6 1.6 1.5 2.8 3.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 3.6 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 7.5 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 15.4 0.0 0.0 0.3 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GANAB "G2AN, GIIA, GluII, KIAA0088" ENSG00000089597 "Glucosidase II alpha subunit" Q14697 11 62624826-62646726 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026874, HPA061426" Enhanced Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA 23000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA026874: AB_1849745, HPA061426: AB_2684516" "unprognostic (2.12e-1)" "unprognostic (5.95e-3)" "unprognostic (4.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-2)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (5.80e-3)" "unprognostic (1.09e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-3)" "unprognostic (5.91e-2)" "unprognostic (1.01e-3)" "unprognostic (3.81e-2)" "unprognostic (1.82e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.54e-4)" 93.9 73.7 31.8 88.2 34.5 83.7 92.8 36.6 36.7 112.6 51.6 104.7 95.6 102.1 151.7 66.4 106.9 75.3 67.9 31.7 41.2 98.5 171.7 86.8 81.7 38.5 34.9 115.5 88.1 130.6 21.8 141.8 38.1 97.5 116.8 79.4 101.8 111.1 39.4 74.7 90.5 126.0 36.5 86.7 85.2 66.1 39.8 105.2 132.6 53.0 94.8 90.7 34.2 43.4 298.2 245.9 318.2 552.0 464.1 389.0 332.9 312.4 480.4 436.2 362.1 222.2 515.9 201.2 616.0 572.5 337.8 376.4 375.2 376.7 443.8 155.8 191.3 202.9 317.8 125.6 389.0 325.7 248.7 397.2 248.4 433.6 475.3 533.0 422.3 199.6 278.5 352.9 398.2 313.6 167.6 193.4 262.3 236.6 237.7 209.5 368.7 513.1 285.7 230.3 168.6 221.2 451.1 308.2 370.8 321.6 380.9 304.8 311.6 430.0 272.2 342.9 309.9 360.8 423.8 152.2 473.9 173.1 421.7 23.9 19.3 19.1 23.8 23.4 23.1 15.9 17.2 20.0 20.8 14.9 20.9 21.3 8.9 29.8 22.2 18.4 17.3 22.6 31.8 34.5 36.6 36.7 31.7 41.2 38.5 34.9 38.1 36.5 39.8 43.4 42.7 12.8 20.7 17.3 29.8 28.3 29.4 45.8 13.6 31.4 57.4 53.8 7.8 52.9 24.2 68.0 60.5 81.7 33.4 40.1 5.9 47.0 18.5 31.4 59.1 42.2 31.8 25.0 12.6 42.6 137.3 45.9 27.5 46.5 11.4 72.8 48.2 98.0 57.9 35.3 16.0 48.9 34.6 45.8 25.1 16.4 58.4 32.7 35.6 15.9 38.9 36.5 38.1 11.1 16.5 39.5 29.3 68.1 50.4 34.0 47.8 27.0 26.3 41.4 32.9 36.4 34.7 25.3 47.4 21.2 31.3 80.2 25.2 63.1 56.3 32.4 GBA "GBA1, GLUC" ENSG00000177628 "Glucosylceramidase beta" P04062 1 155234452-155244699 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Sphingolipid metabolism, Steroid metabolism, Sterol metabolism" "Glycosidase, Glycosyltransferase, Hydrolase, Transferase" "Disease variant, Gaucher disease, Ichthyosis, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 65.2;Syncytiotrophoblasts: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006667, CAB037171, CAB037289" Supported "Intracellular and membrane" NA NA 470000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "CAB037171: AB_1078958, CAB037289: AB_1078957, HPA006667: AB_1078979" "unprognostic (6.03e-2)" "unprognostic (6.02e-2)" "unprognostic (3.41e-1)" "unprognostic (2.42e-1)" "unprognostic (6.00e-3)" "unprognostic (2.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.76e-2)" "unprognostic (1.22e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" "unprognostic (1.33e-1)" "unprognostic (1.47e-1)" "unprognostic (1.76e-1)" "unprognostic (3.04e-2)" "unprognostic (3.15e-1)" "unprognostic (2.94e-2)" 23.9 37.9 22.5 24.8 24.4 41.7 25.1 25.9 24.3 26.7 27.4 35.1 23.9 22.9 50.2 27.6 20.5 28.3 19.1 26.1 27.7 33.6 33.7 28.3 19.9 27.3 28.0 16.9 33.4 103.1 43.8 39.2 36.2 23.3 39.8 12.4 26.8 33.6 9.1 33.4 22.5 29.7 25.0 29.0 22.7 8.8 29.2 19.7 37.7 13.6 28.0 27.1 21.9 29.5 38.0 72.2 25.1 34.2 254.8 55.8 29.3 65.4 230.4 95.3 119.0 43.2 135.7 26.3 70.4 153.7 152.0 76.2 35.9 46.4 50.3 55.5 25.1 21.8 45.1 23.2 73.6 25.8 87.0 73.4 38.2 199.7 30.2 100.2 85.6 22.2 23.4 42.9 113.5 82.6 32.5 11.9 16.3 61.9 51.2 26.8 41.9 108.1 63.9 29.0 23.9 33.5 57.4 136.4 145.3 45.6 102.6 63.3 65.7 71.7 31.7 91.9 53.7 86.2 78.6 20.4 126.6 23.4 56.4 21.4 36.0 15.3 20.8 35.8 13.2 11.1 15.7 13.8 22.4 7.8 11.0 11.7 28.9 11.6 37.2 12.5 23.4 23.3 22.5 24.4 25.9 24.3 26.1 27.7 27.3 28.0 36.2 25.0 29.2 29.5 6.8 3.2 5.1 3.3 8.8 6.0 5.8 9.5 4.6 4.0 12.7 6.5 8.8 17.2 8.1 12.9 2.1 30.7 6.2 36.1 3.9 30.5 1.4 12.3 9.7 12.2 14.6 7.4 3.4 32.4 27.9 18.6 20.9 17.9 7.0 7.9 17.2 23.2 65.2 5.0 2.7 11.6 4.1 33.3 9.9 2.8 9.9 26.8 26.6 1.0 22.8 11.7 12.3 0.5 3.3 29.5 15.8 9.1 19.8 6.7 28.6 20.6 8.5 6.0 0.0 9.4 21.6 22.5 12.5 8.6 4.4 59.4 8.5 6.0 10.4 6.5 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GET3 "ARSA-I, ASNA1, TRC40" ENSG00000198356 "Guided entry of tail-anchored proteins factor 3, ATPase" O43681 19 12737139-12748323 "Predicted intracellular proteins, Transporters" Transport Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cytotrophoblasts: 106.6;Extravillous trophoblasts: 80.7;Hofbauer cells: 142.4;Syncytiotrophoblasts: 110.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045951, HPA048087" Approved Enhanced Nucleoplasm,Nucleoli NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" Nucleoli Nucleoplasm "HPA045951: AB_2679511, HPA048087: AB_2680258" "unprognostic (2.87e-1)" "prognostic favorable (9.53e-4)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (2.05e-2)" "unprognostic (5.70e-2)" "unprognostic (2.01e-2)" "unprognostic (1.33e-2)" "unprognostic (3.34e-1)" "unprognostic (3.08e-2)" "unprognostic (1.85e-1)" "unprognostic (4.39e-2)" "prognostic favorable (4.27e-5)" "unprognostic (6.11e-2)" "unprognostic (5.77e-2)" "unprognostic (2.32e-3)" "prognostic unfavorable (8.47e-4)" 47.5 61.6 56.4 39.4 58.2 66.2 46.5 59.0 72.8 48.4 62.4 43.0 39.9 49.8 41.0 58.1 47.0 39.3 62.0 59.6 58.4 61.6 38.4 40.8 48.3 55.4 57.3 41.9 48.2 73.3 48.2 28.0 57.9 34.3 28.7 36.4 47.3 31.4 67.6 59.1 38.7 33.9 55.9 43.4 50.9 60.2 58.9 46.9 56.3 58.6 38.1 46.3 43.3 57.3 143.7 116.5 60.7 132.3 118.6 72.4 74.6 72.4 99.7 137.5 107.6 90.3 69.6 64.8 111.0 95.4 157.5 75.2 84.5 97.6 65.4 100.9 132.7 54.3 82.4 105.3 125.8 83.5 104.9 83.6 84.1 111.3 66.1 89.2 99.4 75.9 71.3 86.8 109.5 320.4 112.9 68.1 154.6 92.0 215.6 82.2 93.6 128.4 130.2 120.7 111.6 95.5 97.3 131.3 119.8 51.5 108.2 80.5 85.5 193.3 65.4 217.1 172.4 153.9 279.4 61.7 136.2 137.0 109.0 33.6 44.3 26.3 24.8 34.3 21.2 20.3 22.0 22.2 44.8 17.0 15.7 19.5 15.6 16.7 42.9 29.4 34.2 35.8 56.4 58.2 59.0 72.8 59.6 58.4 55.4 57.3 57.9 55.9 58.9 57.3 14.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 106.6 13.1 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 80.7 12.5 0.0 0.0 0.0 0.0 0.0 0.0 142.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 110.7 1.7 0.0 0.0 0.0 GFRA4 ENSG00000125861 "GDNF family receptor alpha 4" Q9GZZ7 20 3659248-3663399 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "thyroid gland: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 1.6;Late spermatids: 3.2;Proximal tubular cells: 1.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 43: Testis - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (3.50e-2)" "unprognostic (2.36e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.2;choroid plexus: 20.5" "Cell type enriched" "Detected in many" 7 "Astrocytes: 649.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 21.5;HSkMC: 29.5;RPTEC TERT1: 20.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA056426 Approved Supported Nucleoplasm "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA056426: AB_2683128" "unprognostic (6.24e-2)" "unprognostic (2.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.63e-3)" "unprognostic (4.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.81e-2)" "unprognostic (7.14e-2)" "unprognostic (4.66e-2)" "unprognostic (1.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-3)" "unprognostic (6.88e-3)" "unprognostic (8.54e-2)" "unprognostic (1.04e-1)" "unprognostic (6.35e-2)" 4.3 1.6 5.1 2.1 5.5 0.2 1.9 4.9 4.6 7.8 20.5 2.0 0.7 3.3 2.8 0.5 8.7 6.5 2.9 5.4 10.8 7.8 3.3 3.8 1.1 24.2 18.0 6.6 9.7 2.4 2.4 1.4 11.4 3.3 2.1 1.3 3.1 8.2 1.3 0.8 1.5 2.1 13.7 2.0 1.8 2.8 6.5 0.2 18.6 0.8 0.7 4.0 2.4 13.2 1.0 8.5 2.5 0.0 3.7 9.5 0.4 5.9 21.5 3.1 4.4 1.3 3.4 0.0 4.3 5.5 9.6 0.0 2.0 0.0 6.7 2.5 1.2 0.0 0.4 0.0 11.0 0.9 0.0 29.5 0.0 9.8 1.1 5.8 0.4 0.1 0.0 0.2 2.9 0.4 0.0 1.5 0.2 0.0 0.8 0.0 5.2 0.0 20.8 0.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 5.5 3.4 0.9 3.2 13.3 0.0 0.0 0.0 8.1 0.0 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 5.1 5.5 4.9 4.6 5.4 10.8 24.2 18.0 11.4 13.7 6.5 13.2 8.1 9.6 24.0 649.7 1.0 1.9 9.3 17.1 0.6 1.0 4.6 1.3 1.6 75.8 34.5 69.9 0.0 3.2 0.3 3.7 0.0 51.0 5.2 79.6 17.5 11.2 43.7 0.0 18.3 22.6 3.2 21.9 4.1 82.3 1.3 1.6 6.8 8.3 2.4 0.0 54.2 1.6 12.2 0.8 4.0 2.4 13.7 3.4 3.6 86.2 2.2 15.6 0.0 26.7 4.1 49.1 3.9 11.3 0.0 16.5 2.4 16.4 35.7 0.4 0.0 34.4 19.0 1.3 7.4 0.6 1.3 4.2 1.2 8.8 6.6 6.1 GLOD5 ENSG00000171433 "Glyoxalase domain containing 5" A6NK44 X 48761747-48773648 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "epididymis: 5.8;intestine: 10.6;kidney: 11.2;liver: 8.2" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 45.2;Proximal tubular cells: 70.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA010667 Enhanced Uncertain Mitochondria NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA010667: AB_1078975" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (7.78e-2)" "unprognostic (7.04e-2)" "unprognostic (3.14e-1)" "unprognostic (6.11e-2)" "unprognostic (1.80e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-1)" "unprognostic (2.21e-1)" "unprognostic (1.05e-8)" "unprognostic (2.08e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (6.79e-4)" 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.1 0.3 0.0 4.7 10.6 0.0 5.8 0.1 1.9 0.8 0.0 0.0 0.0 11.2 8.2 1.3 0.0 0.1 0.0 0.0 0.7 0.1 0.3 0.0 0.1 0.2 6.1 1.9 0.3 0.3 0.0 0.0 10.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 3.2 2.6 1.3 0.5 0.0 0.3 0.2 0.0 0.6 8.3 1.0 0.0 4.3 0.3 7.3 0.0 0.1 0.0 14.4 13.7 0.6 0.2 3.0 0.1 0.0 1.2 2.7 0.2 0.9 0.1 0.0 0.0 1.1 0.0 0.1 0.0 8.0 0.0 0.0 0.3 7.3 0.0 0.3 0.0 0.2 0.0 0.5 0.0 0.0 0.6 0.5 0.0 0.5 0.5 0.8 13.9 0.0 0.1 0.3 45.2 70.5 2.7 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 8.9 0.7 GLRX5 "C14orf87, GRX5, PR01238" ENSG00000182512 "Glutaredoxin 5" Q86SX6 14 95533503-95544724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 518.5;Erythroid cells: 1134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042465, HPA063716" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "HPA042465: AB_10794048, HPA063716: AB_2685102" "unprognostic (2.57e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-2)" "unprognostic (2.69e-2)" "unprognostic (3.72e-2)" "unprognostic (2.43e-3)" "unprognostic (1.29e-1)" "unprognostic (5.41e-2)" "unprognostic (8.28e-2)" "prognostic favorable (1.08e-5)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "prognostic favorable (7.83e-10)" "unprognostic (1.44e-1)" "unprognostic (3.81e-2)" "unprognostic (2.66e-2)" "unprognostic (8.91e-2)" 37.2 52.1 44.1 17.6 44.9 178.8 27.2 43.8 50.2 22.3 46.7 44.8 46.2 19.2 39.0 24.5 23.6 17.5 76.9 46.6 45.8 74.5 105.5 18.3 23.1 43.3 44.5 32.8 31.5 46.3 18.9 37.8 44.3 26.8 37.3 10.1 29.3 29.6 195.0 18.3 33.2 24.4 42.9 20.8 34.2 35.7 46.2 40.3 26.7 168.9 27.0 24.5 15.0 42.9 77.1 92.7 61.4 68.0 74.2 57.5 202.0 54.9 56.1 69.4 69.1 124.8 87.5 111.7 77.4 42.8 39.2 75.5 116.5 79.6 71.5 68.5 94.4 100.3 63.4 202.2 73.5 160.9 96.5 55.4 74.1 49.9 81.1 28.1 76.1 94.4 115.7 88.3 61.2 205.5 133.6 165.9 81.5 89.7 107.8 220.8 184.3 67.8 93.3 89.3 127.9 75.2 54.8 81.3 87.7 59.9 107.7 72.6 55.6 30.5 65.0 77.6 85.7 41.7 57.9 92.0 67.2 99.8 72.2 0.4 2.9 4.8 3.4 4.3 4.9 4.6 4.6 6.0 4.7 5.4 3.7 3.9 1.3 3.9 2.7 9.0 6.2 1.8 44.1 44.9 43.8 50.2 46.6 45.8 43.3 44.5 44.3 42.9 46.2 42.9 78.7 28.9 30.0 7.8 41.1 108.5 58.7 7.5 61.5 38.5 112.8 135.9 150.0 64.3 10.4 95.6 33.3 97.8 66.5 76.3 518.5 15.2 312.0 49.7 61.5 58.9 54.0 1134.9 15.0 15.6 164.9 66.2 46.4 48.3 14.7 110.3 47.2 147.2 58.7 50.5 16.4 72.1 4.1 41.7 58.7 90.2 54.3 50.7 87.2 7.5 21.3 128.1 52.5 12.5 15.2 15.2 39.5 73.7 75.2 108.2 51.8 281.4 9.1 43.0 59.2 61.1 92.7 115.4 79.0 102.2 124.9 53.8 48.8 169.0 88.0 76.6 GLTP ENSG00000139433 "Glycolipid transfer protein" Q9NZD2 12 109850945-109880541 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 334.1;skin 1: 276.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 266.5;Suprabasal keratinocytes: 479.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056461, HPA065503" Approved Supported Cytosol NA NA 25000 "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA056461: AB_2683138, HPA065503: " "unprognostic (1.18e-1)" "prognostic favorable (2.01e-5)" "unprognostic (7.46e-2)" "unprognostic (6.22e-3)" "unprognostic (1.95e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (6.63e-2)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (2.47e-1)" "unprognostic (3.03e-1)" "unprognostic (4.83e-2)" "unprognostic (4.46e-2)" "unprognostic (2.20e-1)" "prognostic favorable (4.17e-6)" "unprognostic (3.28e-2)" 19.0 21.7 59.1 17.5 98.8 19.3 27.1 93.6 75.1 94.4 43.1 38.4 14.6 15.9 34.8 334.1 13.6 14.2 21.0 62.3 69.9 53.2 15.1 24.4 19.3 110.3 89.5 18.2 23.8 31.4 12.5 17.8 102.5 29.4 31.8 7.0 84.7 19.1 18.6 276.6 32.1 18.8 84.0 21.5 21.6 16.3 87.3 18.0 23.5 18.1 108.2 33.6 178.0 138.5 39.3 27.9 15.5 16.7 36.2 41.4 11.0 47.4 58.2 36.0 29.7 11.3 14.9 34.5 25.3 57.8 17.5 47.3 24.2 54.9 50.7 35.0 21.5 22.6 15.9 16.5 31.6 24.6 25.5 30.1 68.8 64.6 45.3 53.9 61.3 34.8 10.1 22.5 53.2 52.9 33.6 19.8 28.1 32.0 36.8 29.3 36.4 36.3 20.5 116.1 20.0 19.8 30.1 77.1 26.0 14.1 36.1 8.6 83.2 41.4 21.9 61.5 36.5 30.1 27.7 23.8 83.0 25.1 25.9 42.6 65.7 37.3 51.5 66.0 32.4 23.9 31.0 46.5 48.8 21.5 20.1 35.8 32.9 42.4 57.0 8.0 37.6 40.6 59.1 98.8 93.6 75.1 62.3 69.9 110.3 89.5 102.5 84.0 87.3 138.5 48.1 25.6 60.9 10.4 37.5 145.4 109.1 72.1 88.2 11.4 55.6 44.4 14.6 18.6 62.7 44.1 14.6 86.5 48.3 95.6 199.6 39.0 20.5 30.1 33.3 47.9 32.4 10.1 9.9 56.5 20.0 35.0 28.5 59.1 20.8 19.0 34.2 15.3 34.5 13.5 11.4 39.2 50.8 61.6 84.6 11.7 23.0 55.3 60.5 13.1 61.8 23.4 64.9 21.6 140.1 53.5 40.0 18.0 26.2 80.6 102.3 38.2 25.2 12.3 39.5 23.5 37.3 22.9 20.8 266.5 479.2 210.6 46.3 31.4 59.1 129.0 GOT2 "KAT4, KATIV, KYAT4, mitAAT" ENSG00000125166 "Glutamic-oxaloacetic transaminase 2" P00505 16 58707131-58734342 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Aminotransferase, Transferase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 698.4;tongue: 726.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 341.9;Hepatocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018139, HPA058537" Enhanced "Intracellular and membrane" NA NA 2800000 "Cluster 13: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA018139: AB_1849903, HPA058537: " "unprognostic (1.50e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-3)" "unprognostic (2.63e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (1.61e-4)" "prognostic favorable (5.75e-5)" "unprognostic (1.12e-2)" "unprognostic (3.19e-1)" "unprognostic (3.72e-2)" "unprognostic (2.27e-1)" "unprognostic (3.00e-1)" "prognostic favorable (2.90e-9)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.56e-2)" "unprognostic (2.22e-1)" 19.6 73.9 52.4 27.4 55.9 21.1 36.3 62.5 66.9 34.1 129.4 57.6 37.4 36.5 66.3 66.9 46.7 24.1 313.2 57.9 59.3 88.0 321.4 25.2 35.6 60.6 51.0 29.4 33.2 98.6 46.7 24.7 62.5 59.0 65.0 91.4 47.7 65.7 698.4 41.1 35.7 46.7 50.1 28.5 54.9 28.9 58.7 35.9 42.6 726.8 57.0 57.0 45.1 61.0 137.2 182.4 93.8 114.8 66.6 59.8 122.0 101.4 108.8 197.6 107.7 158.9 120.1 302.3 117.3 114.6 86.5 195.5 203.2 199.2 250.1 83.1 182.0 81.4 92.1 179.3 84.2 132.3 71.9 58.4 110.9 125.2 108.2 112.4 201.8 141.9 167.0 30.6 102.2 122.5 164.0 128.0 127.7 90.8 338.0 177.8 142.7 291.1 187.9 197.7 148.2 107.6 195.2 208.5 74.8 84.2 105.5 42.7 82.3 71.4 129.3 56.2 132.4 69.9 68.6 247.4 76.7 130.9 73.8 4.6 20.6 7.4 28.3 16.9 43.7 26.5 33.1 34.1 34.7 22.3 30.1 28.4 1.8 30.2 18.4 30.0 48.7 31.2 52.4 55.9 62.5 66.9 57.9 59.3 60.6 51.0 62.5 50.1 58.7 61.0 15.1 9.6 15.8 11.8 19.8 32.0 37.0 39.4 34.1 34.5 27.5 16.3 341.9 22.8 22.5 36.8 77.2 42.6 11.8 42.6 56.7 50.8 4.0 30.4 20.0 23.8 20.5 39.3 24.7 42.5 38.8 21.1 30.1 25.4 14.5 37.5 23.2 176.1 39.1 20.2 27.1 33.5 26.4 17.0 15.1 8.1 18.0 13.5 24.9 5.6 12.7 16.1 8.2 11.6 17.6 40.3 13.3 22.6 39.2 38.2 27.6 63.2 17.5 48.9 0.0 15.2 24.0 11.9 15.0 68.9 30.0 23.7 17.4 36.4 54.4 69.6 GPR107 "FLJ20998, KIAA1624, LUSTR1, RP11-88G17" ENSG00000148358 "G protein-coupled receptor 107" Q5VW38 9 130053426-130140169 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031704 Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Nucleoplasm "HPA031704: AB_10601018" "prognostic unfavorable (3.56e-5)" "unprognostic (7.48e-2)" "unprognostic (6.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (8.72e-2)" "unprognostic (1.10e-3)" "unprognostic (1.35e-2)" "unprognostic (2.18e-1)" "unprognostic (3.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.85e-1)" "prognostic favorable (1.87e-5)" "unprognostic (4.10e-2)" "unprognostic (5.83e-2)" "unprognostic (6.50e-2)" "unprognostic (1.34e-3)" 18.9 17.3 21.0 15.1 22.1 12.2 20.3 21.9 21.3 20.1 24.4 21.3 11.6 18.8 15.3 18.7 22.0 16.1 18.3 19.5 23.9 20.5 13.0 20.3 11.0 23.4 25.3 17.9 18.8 28.7 16.6 23.3 25.6 23.6 22.6 26.3 18.3 19.9 17.8 22.7 12.9 23.2 21.8 13.4 16.7 17.3 23.5 14.3 34.9 17.0 14.2 15.8 14.2 23.8 29.7 42.0 39.6 31.7 42.4 44.6 39.9 45.9 52.5 37.9 37.5 40.6 39.5 16.4 33.4 52.1 44.5 73.0 30.7 28.6 32.3 24.7 20.3 17.0 49.1 23.8 40.9 36.2 24.4 37.5 44.3 38.1 38.7 44.1 35.9 19.0 25.0 15.8 33.6 36.6 19.4 14.7 26.8 60.0 31.7 18.3 58.7 25.9 32.1 40.2 13.6 30.7 59.8 42.8 33.1 34.9 75.0 19.3 42.9 48.1 25.1 40.3 35.3 9.8 35.6 15.2 43.5 17.0 46.9 1.5 2.8 1.9 0.7 3.4 1.0 1.0 0.7 0.8 1.8 1.0 0.5 1.2 3.3 0.9 3.6 1.1 0.7 1.3 21.0 22.1 21.9 21.3 19.5 23.9 23.4 25.3 25.6 21.8 23.5 23.8 14.8 25.6 19.3 47.7 8.0 6.4 5.1 14.8 5.2 16.9 17.8 12.2 23.0 14.3 16.4 16.5 39.6 15.4 11.4 20.7 0.0 13.4 6.5 23.7 19.3 14.3 9.6 4.6 32.7 17.6 19.2 16.2 16.8 26.4 6.3 17.9 24.3 11.6 15.1 18.5 39.7 19.4 6.1 17.0 17.6 5.7 19.0 13.8 14.2 22.5 15.6 11.0 9.2 38.2 48.6 21.9 15.9 19.2 11.2 13.2 9.3 6.5 24.5 15.5 0.0 16.3 15.3 16.2 11.5 12.2 10.9 26.7 10.4 13.5 18.4 10.9 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 42.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 251.4;Kupffer cells: 173.3;Macrophages: 100.6;Microglial cells: 54.4" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 339.6;eosinophil: 117.9" "Lineage enriched" "Detected in many" 24 "granulocytes: 339.6" "Cell line enhanced" "Detected in single" "HMC-1: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" 28.2 17.1 5.2 15.1 5.2 0.9 21.5 6.1 5.8 14.0 5.6 12.0 6.5 6.7 2.7 8.2 7.8 17.0 8.3 5.0 7.6 5.0 8.5 10.9 20.0 10.6 7.9 7.3 5.4 5.3 1.4 42.7 11.4 3.2 13.1 0.6 3.6 8.8 0.8 1.0 14.6 16.3 9.9 15.6 7.8 2.7 9.7 6.9 3.7 4.6 16.7 13.3 1.7 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 339.6 9.7 117.9 0.0 12.9 0.4 1.5 0.4 0.1 2.0 1.2 0.1 0.3 1.1 14.3 7.0 0.3 0.6 2.8 5.2 5.2 6.1 5.8 5.0 7.6 10.6 7.9 11.4 9.9 9.7 18.8 0.9 0.0 2.8 1.0 2.0 0.6 0.2 0.0 0.0 0.0 0.5 2.3 1.2 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.6 0.1 0.1 5.0 1.2 0.4 0.7 0.0 1.6 1.0 0.5 0.0 37.3 0.0 2.9 0.8 251.4 0.0 0.9 0.0 0.0 173.3 13.6 1.9 0.9 100.6 1.8 54.4 7.1 0.1 1.0 3.5 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.1 0.0 0.8 19.7 0.6 0.3 0.0 0.2 0.4 1.0 2.5 7.2 0.1 0.1 0.0 GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 12.1;Early spermatids: 20.6;Late spermatids: 19.4;Oligodendrocyte precursor cells: 18.6;Spermatocytes: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "A-431: 32.0;CAPAN-2: 26.9;hTEC/SVTERT24-B: 30.8;RT4: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" 0.2 0.0 0.7 0.9 0.7 0.0 2.1 0.5 0.7 4.4 1.3 6.8 4.6 0.4 0.8 0.8 3.6 2.2 0.0 0.4 0.7 2.6 3.3 3.9 0.0 1.6 2.2 0.0 3.9 5.1 0.1 0.1 2.0 0.5 5.7 0.0 0.5 1.0 0.0 1.0 3.7 0.3 1.2 0.0 6.1 0.2 0.7 0.0 1.3 0.0 0.2 2.6 0.6 0.2 32.0 18.1 0.3 0.0 0.5 3.6 0.0 2.8 11.1 5.8 3.3 17.7 26.9 0.0 9.7 1.9 13.1 18.6 0.0 12.9 5.7 0.1 0.0 0.0 1.9 0.7 0.6 0.0 0.0 1.1 9.7 30.8 3.1 7.0 0.1 0.0 0.0 0.0 4.2 3.0 0.0 0.0 0.3 7.3 10.5 0.0 0.5 0.0 21.2 27.9 0.0 0.1 2.0 10.3 0.1 1.1 5.8 0.0 5.6 12.4 12.2 4.2 16.8 0.0 0.0 0.1 18.9 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.7 0.5 0.7 0.4 0.7 1.6 2.2 2.0 1.2 0.7 0.2 0.0 16.0 8.7 12.1 0.0 0.1 0.7 2.4 0.0 0.2 1.5 0.9 0.2 2.8 6.7 0.0 0.0 0.0 2.7 10.3 0.0 5.6 20.6 2.6 0.2 0.1 2.4 0.0 3.9 3.1 0.0 0.2 4.1 1.8 0.0 0.0 0.0 3.6 0.0 0.0 4.9 1.6 0.0 0.6 0.3 19.4 0.3 0.3 0.0 1.0 0.6 1.4 0.0 18.6 1.8 5.9 3.0 0.4 0.1 0.3 1.9 0.7 6.1 0.0 0.0 0.1 0.3 32.4 1.2 0.5 0.0 0.0 0.0 0.0 4.9 1.2 GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 192.7;stomach 1: 230.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3;Gastric mucus-secreting cells: 143.2;Hepatocytes: 183.6;Paneth cells: 153.8;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.7" "Cell line enhanced" "Detected in many" "Hep G2: 82.4;HMC-1: 146.7;PC-3: 80.8;RPTEC TERT1: 172.1;RT4: 89.9;T-47d: 108.0" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" 16.1 19.3 17.4 3.1 18.4 0.4 20.1 48.9 18.1 42.0 28.0 38.7 25.0 17.1 10.2 12.2 30.0 21.3 33.7 14.8 16.9 135.7 192.7 23.0 2.1 18.1 18.7 38.2 136.1 28.2 14.8 11.9 18.6 45.6 14.6 1.5 37.4 24.3 110.1 43.9 30.3 4.0 16.6 22.3 230.3 4.0 17.0 4.4 74.8 33.9 3.0 30.8 20.9 15.7 17.3 61.6 3.8 5.5 0.0 0.0 0.2 0.3 0.0 0.0 0.0 66.4 73.0 0.0 45.0 0.3 18.5 52.9 7.7 1.0 0.1 0.2 10.7 0.0 4.0 82.4 15.8 0.0 146.7 1.3 26.7 0.0 0.0 69.2 0.0 0.1 4.8 1.2 0.0 18.0 0.7 17.2 9.2 79.5 80.8 0.2 0.1 2.8 172.1 89.9 27.5 2.5 3.7 5.9 0.1 33.1 108.0 4.6 0.0 0.0 5.5 0.1 0.1 0.1 0.4 0.2 6.5 2.5 0.4 0.0 1.1 0.1 0.0 2.5 0.0 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 3.7 7.9 0.0 0.3 17.4 18.4 48.9 18.1 14.8 16.9 18.1 18.7 18.6 16.6 17.0 15.7 11.2 3.2 57.7 13.4 1.4 13.6 39.2 79.6 26.7 0.8 27.3 19.4 211.3 67.2 76.2 136.1 0.0 0.8 11.8 74.9 29.4 65.5 0.1 62.5 6.6 20.9 45.5 5.3 0.1 68.1 20.3 11.3 143.2 74.9 10.2 0.1 48.2 183.6 12.3 5.0 0.5 50.8 69.2 16.3 4.6 1.7 18.0 6.3 3.6 2.8 4.1 15.9 0.0 5.0 0.2 41.2 153.8 22.2 1.2 44.6 61.0 73.5 45.4 1.5 144.7 4.7 64.0 0.5 5.0 14.8 11.2 25.3 2.4 1.5 48.5 63.1 GPX7 "FLJ14777, GPX6, NPGPx" ENSG00000116157 "Glutathione peroxidase 7" Q96SL4 1 52602371-52609051 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 68.6;HEL: 63.9;REH: 76.4;RPMI-8226: 130.0;THP-1: 101.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (5.87e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (7.43e-3)" "unprognostic (3.18e-1)" "unprognostic (5.64e-2)" "unprognostic (6.12e-3)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (8.18e-2)" "unprognostic (4.17e-1)" "unprognostic (2.48e-3)" "prognostic unfavorable (2.26e-5)" "unprognostic (1.14e-2)" "unprognostic (9.24e-2)" "unprognostic (3.08e-2)" "unprognostic (5.44e-2)" 8.4 7.9 4.8 12.4 5.0 18.3 11.9 5.2 5.4 11.6 9.3 9.4 3.3 13.1 7.3 4.3 9.1 13.4 10.8 4.6 5.9 6.9 5.3 6.8 16.5 5.2 5.1 8.9 11.5 8.5 12.5 29.3 5.0 8.7 5.5 1.7 5.9 9.7 12.1 5.0 6.0 10.8 5.0 8.1 5.0 5.5 5.0 15.9 17.1 11.5 14.0 12.4 6.9 4.9 0.1 0.0 18.1 33.9 6.6 19.1 0.1 12.5 0.7 14.8 15.3 12.2 0.0 0.1 9.8 68.6 0.0 0.0 29.0 0.0 8.1 0.0 0.2 63.9 3.6 11.3 23.9 0.0 0.0 44.4 0.0 2.5 0.0 0.0 22.9 0.4 0.0 0.0 28.2 0.0 3.3 33.5 31.5 0.0 0.0 76.4 0.0 130.0 1.3 0.0 13.7 27.0 33.3 0.0 21.9 3.0 0.0 101.1 1.4 0.0 3.7 3.8 0.1 0.1 0.0 47.9 0.0 0.2 11.3 0.2 1.7 5.4 22.6 0.4 31.8 32.0 34.6 27.1 5.4 35.2 44.5 29.0 0.9 31.6 0.2 73.7 27.6 21.4 4.8 5.0 5.2 5.4 4.6 5.9 5.2 5.1 5.0 5.0 5.0 4.9 8.4 3.2 5.5 1.0 16.1 2.2 9.0 8.3 1.2 1.0 7.1 13.6 3.9 12.8 6.5 3.7 0.0 22.8 9.2 0.2 5.9 11.1 6.9 8.2 43.7 12.4 1.2 6.7 1.6 15.6 19.8 30.5 0.5 6.5 1.3 25.8 15.4 3.8 12.3 5.0 2.7 1.2 2.0 1.9 0.7 6.6 15.2 6.0 7.2 4.7 5.0 8.3 9.2 4.5 2.0 4.7 0.7 13.5 25.2 5.7 0.0 3.0 7.0 0.6 13.1 13.3 14.5 10.8 12.1 1.9 3.3 15.6 10.9 19.3 0.6 4.9 GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 32.6;granulocytes: 146.9;Macrophages: 82.0;NK-cells: 59.8;T-cells: 57.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Group enriched" "Detected in some" 4 "HEL: 45.7;JURKAT: 175.8;K-562: 44.8;MOLT-4: 122.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" 1.2 0.7 0.2 7.9 0.2 10.3 2.0 0.2 0.3 1.5 0.5 2.2 3.6 0.8 0.5 1.2 0.7 2.6 1.1 0.2 0.3 0.6 1.2 4.4 15.7 0.6 0.3 0.2 0.4 0.1 0.3 0.6 0.5 1.6 2.3 0.3 1.7 0.7 0.4 1.1 4.5 0.9 0.5 9.3 3.8 1.9 0.4 184.8 0.8 0.5 12.9 3.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 45.7 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.2 0.3 0.0 175.8 44.8 0.0 0.0 0.0 122.8 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 6.3 0.7 0.1 51.4 0.3 38.2 3.1 37.5 56.2 1.2 5.2 31.3 58.2 6.6 5.4 0.3 0.8 35.0 74.9 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.3 0.5 0.5 0.4 0.7 1.1 0.0 6.7 0.3 8.2 1.7 0.0 0.0 0.0 0.6 1.1 0.8 1.0 2.8 0.0 0.0 0.0 0.0 18.3 0.1 0.0 0.4 4.8 0.3 0.1 0.8 1.2 32.6 1.3 0.2 0.0 0.6 0.0 0.1 146.9 0.2 2.5 2.3 0.2 0.0 1.2 0.6 0.0 1.9 4.6 2.9 0.3 82.0 1.8 1.0 6.8 0.3 59.8 2.5 1.0 0.0 0.3 0.4 6.3 0.4 0.0 0.4 0.0 0.0 0.0 0.5 0.9 4.4 2.1 0.1 1.1 0.1 57.1 0.0 0.1 0.3 GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242242-21525417 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.2;Inhibitory neurons: 39.2;Leydig cells: 46.0;Oligodendrocytes: 252.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 50.7;BEWO: 100.9;CACO-2: 45.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" 2.6 1.4 5.5 0.1 4.3 0.2 3.3 3.5 3.6 1.2 0.0 0.6 0.1 2.6 2.8 0.2 4.4 0.1 5.3 2.6 8.1 0.4 1.8 0.2 0.1 4.0 4.7 3.7 0.1 0.3 1.2 2.1 4.1 1.6 0.1 3.1 0.5 2.9 9.2 1.3 0.5 0.8 1.7 0.0 0.6 6.2 6.4 0.0 3.8 6.8 0.0 0.1 0.7 4.4 0.0 0.9 50.7 0.0 11.4 0.0 100.9 2.4 2.4 4.3 3.8 45.7 3.7 0.1 5.1 7.6 0.1 9.7 19.4 2.4 7.5 0.7 9.3 0.0 13.4 0.4 0.3 0.0 0.0 0.0 0.7 0.1 9.3 0.5 0.0 1.4 0.0 0.3 10.5 3.5 0.2 0.2 4.9 0.4 6.0 0.2 0.0 2.0 4.8 8.7 3.2 0.0 0.1 1.6 0.2 13.2 2.7 0.2 20.9 0.5 2.9 4.9 0.0 0.1 0.7 0.0 2.2 0.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 4.3 3.5 3.6 2.6 8.1 4.0 4.7 4.1 1.7 6.4 4.4 0.4 0.0 0.5 0.7 0.4 0.1 0.1 1.0 0.0 32.3 3.1 1.1 13.4 0.0 1.1 3.7 2.1 3.2 1.8 0.1 0.0 0.2 8.3 2.2 3.4 0.5 0.0 0.0 23.1 0.4 13.2 6.2 0.0 7.0 0.0 95.2 0.0 3.1 0.5 0.0 39.2 0.2 0.0 0.0 1.1 17.9 46.0 0.3 1.8 2.8 0.1 0.8 2.1 8.0 252.5 2.8 0.0 35.7 0.0 0.6 0.3 0.0 2.3 1.6 6.6 2.8 2.3 4.3 5.6 0.0 0.9 1.5 0.3 10.5 1.5 0.2 GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;stomach 1: 12.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 24.4;Early spermatids: 15.5;Ionocytes: 6.1;Late spermatids: 12.2;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in all" 4 "midbrain: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ hTERT+: 5.1;fHDF/TERT166: 6.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 24.9" "Secreted in other tissues" NA NA 340000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" 0.3 0.2 3.2 0.2 2.6 0.0 2.6 1.3 5.0 0.1 2.8 2.1 0.1 0.3 0.3 0.0 0.0 0.3 0.0 6.1 6.0 0.4 0.0 9.0 0.0 3.0 26.1 0.0 1.2 7.0 3.9 0.0 2.4 2.7 0.1 0.5 0.0 0.1 0.0 0.4 0.7 1.2 2.6 0.3 12.3 2.4 3.5 0.1 6.1 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.0 0.0 0.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 1.3 5.0 6.1 6.0 3.0 26.1 2.4 2.6 3.5 1.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.2 0.0 0.0 0.4 24.4 0.1 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 2.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.3 12.2 0.3 0.1 0.0 4.7 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.1 6.6 0.0 0.2 1.2 0.9 0.0 0.0 0.0 0.3 0.0 0.0 4.2 GRSF1 ENSG00000132463 "G-rich RNA sequence binding factor 1" Q12849 4 70815783-70839897 "Predicted intracellular proteins" "mRNA processing, tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 275.2" "Cell type enhanced" "Detected in all" "monocytes: 301.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036984, HPA036985" Enhanced Enhanced Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" Mitochondria "HPA036984: AB_2675415, HPA036985: AB_10672785" "unprognostic (1.45e-3)" "unprognostic (1.82e-2)" "prognostic favorable (1.47e-5)" "unprognostic (8.63e-2)" "unprognostic (6.73e-2)" "unprognostic (4.15e-3)" "prognostic unfavorable (8.29e-5)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (7.68e-2)" "unprognostic (8.05e-2)" "prognostic favorable (2.72e-9)" "unprognostic (6.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-3)" 38.0 61.2 38.4 36.9 37.7 23.7 37.7 42.5 47.1 36.3 58.9 54.6 43.1 32.5 34.0 42.0 43.0 35.2 80.7 41.0 44.5 55.8 54.4 35.5 47.4 40.3 42.3 38.4 62.0 48.8 21.5 43.8 41.6 39.9 62.7 25.4 83.9 35.3 275.2 32.0 41.3 40.0 40.7 34.6 50.8 32.8 40.9 76.0 45.7 155.0 53.7 50.3 25.8 46.1 116.9 78.1 90.0 94.5 93.5 108.1 128.3 138.2 87.3 102.3 83.5 80.5 117.1 167.6 102.9 143.7 53.0 43.4 161.3 108.6 135.9 91.3 52.8 88.4 75.2 112.4 115.1 130.8 48.7 91.9 102.2 103.6 71.6 123.0 106.9 91.9 102.6 94.7 144.2 124.9 217.4 92.0 96.3 127.1 80.9 88.2 139.8 71.6 126.1 144.0 93.4 84.0 65.3 183.6 234.3 104.7 79.8 63.3 98.4 95.1 99.7 79.4 88.7 78.1 66.2 106.4 78.6 83.6 94.5 12.7 17.4 7.7 10.1 12.3 12.2 7.4 14.6 15.5 28.1 6.1 14.4 12.6 2.0 20.0 15.2 27.2 13.3 8.4 38.4 37.7 42.5 47.1 41.0 44.5 40.3 42.3 41.6 40.7 40.9 46.1 27.8 32.1 36.6 19.6 38.0 50.0 53.7 32.9 48.3 18.2 37.7 28.3 135.5 40.0 30.4 27.6 25.0 106.2 57.4 52.9 74.3 70.3 7.6 53.8 40.4 33.0 69.0 41.2 35.1 61.3 141.3 41.2 65.2 44.5 17.2 60.2 35.0 50.9 63.2 28.6 30.5 73.5 36.7 66.3 53.7 6.7 34.8 45.4 62.2 24.4 301.5 23.8 41.2 21.6 28.0 60.1 46.7 39.1 58.7 65.9 47.1 74.1 27.6 19.6 19.7 38.4 46.2 35.0 61.8 69.7 50.4 77.2 45.1 99.0 89.3 67.0 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 GZMM "LMET1, MET1" ENSG00000197540 "Granzyme M" P51124 19 544034-549924 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cytolysis, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.6;lymphoid tissue: 22.7" "Group enriched" "Detected in many" 13 "dendritic cells: 385.8;NK-cells: 810.5;T-cells: 243.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 583.9" "Group enriched" "Detected in all" 33 "NK-cells: 194.9;T-cells: 583.9" "Cell line enhanced" "Detected in some" "EFO-21: 2.1;HDLM-2: 1.7;HMC-1: 2.1;JURKAT: 3.5;MOLT-4: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015624 Enhanced "Secreted to blood" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA015624: AB_2669245" "unprognostic (2.97e-3)" "unprognostic (2.29e-3)" "unprognostic (7.53e-2)" "prognostic favorable (1.89e-4)" "unprognostic (1.07e-1)" "prognostic favorable (1.87e-7)" "unprognostic (2.35e-1)" "unprognostic (7.46e-2)" "unprognostic (1.67e-1)" "unprognostic (4.98e-2)" "unprognostic (4.53e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.32e-1)" "unprognostic (9.51e-2)" "unprognostic (2.69e-3)" "unprognostic (9.94e-2)" 2.2 1.1 0.9 10.0 0.9 21.6 1.1 3.6 2.0 1.4 0.3 1.5 2.1 0.8 0.2 0.8 1.3 1.8 0.8 0.9 0.9 1.0 3.3 5.3 19.2 1.0 0.8 0.7 0.4 0.0 0.9 0.4 1.0 1.3 0.3 0.2 2.8 0.4 0.7 0.8 6.2 0.2 0.7 22.7 3.7 1.8 0.9 8.7 1.6 0.1 3.8 1.5 1.4 1.0 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.2 0.1 0.0 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.1 0.0 0.4 1.3 0.6 0.3 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.1 0.5 0.1 0.3 0.1 9.1 1.4 1.3 583.9 1.7 366.5 0.9 189.2 471.3 1.5 4.0 182.8 379.2 11.9 194.9 2.3 3.6 99.1 227.5 0.9 0.9 3.6 2.0 0.9 0.9 1.0 0.8 1.0 0.7 0.9 1.0 3.4 0.0 0.0 0.3 5.7 3.1 0.1 0.0 0.6 0.5 2.4 2.2 0.1 1.5 0.0 0.0 0.0 0.2 385.8 0.1 0.0 0.4 0.9 0.6 1.5 1.4 0.0 12.0 0.3 0.4 0.4 2.2 13.3 1.1 0.0 0.1 3.6 1.4 0.2 0.0 0.2 0.4 0.0 3.7 4.7 1.6 0.0 5.9 1.8 1.0 8.6 1.6 810.5 0.5 0.3 0.3 0.0 0.0 35.8 0.1 0.0 1.2 0.0 1.4 0.0 1.5 1.2 0.5 1.1 0.9 1.4 0.5 243.6 0.2 0.1 0.1 HACD3 "B-ind1, HSPC121, PTPLAD1" ENSG00000074696 "3-hydroxyacyl-CoA dehydratase 3" Q9P035 15 65530418-65578349 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014837, HPA060347" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA014837: AB_1855914, HPA060347: AB_2684260" "unprognostic (1.51e-2)" "unprognostic (2.89e-1)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (3.52e-1)" "unprognostic (1.92e-2)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (3.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.57e-1)" "prognostic favorable (3.09e-5)" "unprognostic (3.44e-2)" "unprognostic (5.33e-2)" "unprognostic (1.10e-2)" "unprognostic (2.04e-2)" 23.1 84.1 56.1 18.5 57.1 17.3 74.4 64.6 67.5 40.2 73.2 30.0 28.9 29.9 43.0 19.2 32.4 34.1 11.8 54.3 87.8 79.6 119.1 30.3 18.8 68.3 79.6 47.8 29.8 61.5 44.2 37.2 87.2 41.6 34.3 54.0 28.6 34.3 6.9 27.7 29.2 28.1 70.0 21.2 68.7 34.6 88.3 29.0 70.8 7.8 20.3 43.0 17.8 75.8 88.9 194.4 211.3 106.2 130.3 78.0 99.8 95.9 82.4 106.6 119.6 149.9 129.1 110.8 81.8 104.7 132.6 237.9 344.4 80.1 94.8 61.9 191.8 88.1 88.7 165.3 65.9 110.6 64.9 80.3 58.7 73.3 52.5 102.7 105.5 65.1 117.5 40.8 174.3 105.6 82.5 86.0 180.6 235.3 65.4 91.8 178.9 125.0 152.1 151.2 126.8 111.9 103.6 114.9 110.5 197.5 117.1 57.9 84.2 134.4 117.6 66.9 134.9 79.1 251.2 154.5 89.7 105.8 82.6 8.5 7.5 2.5 31.7 11.2 36.1 23.7 28.6 30.2 13.2 22.2 33.0 32.9 1.0 23.2 12.7 17.4 24.6 22.7 56.1 57.1 64.6 67.5 54.3 87.8 68.3 79.6 87.2 70.0 88.3 75.8 63.6 64.1 64.8 84.5 18.7 0.0 60.5 0.0 76.2 121.3 94.8 64.5 9.9 62.9 27.9 176.6 100.1 189.1 23.8 6.1 25.4 71.3 107.2 62.8 76.2 51.8 43.7 67.3 57.5 46.3 124.4 62.7 73.4 39.8 16.4 127.0 42.1 165.2 51.2 139.7 97.1 26.3 0.0 23.1 0.0 32.5 87.3 22.2 0.0 29.0 5.2 89.8 16.5 57.8 66.7 32.1 18.2 88.4 28.9 71.5 28.3 56.2 36.5 83.7 78.9 40.9 41.9 156.9 110.3 54.3 0.0 113.1 22.3 136.2 45.1 78.7 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HDAC1 "GON-10, HD1, KDAC1, RPD3L1" ENSG00000116478 "Histone deacetylase 1" Q13547 1 32292083-32333635 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005017, HPA029693, CAB068191" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB005017: AB_2248344, CAB068191: AB_2665664, HPA029693: AB_10601659" "unprognostic (2.51e-2)" "unprognostic (9.10e-2)" "unprognostic (2.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.15e-2)" "unprognostic (3.57e-3)" "prognostic unfavorable (5.76e-7)" "unprognostic (9.57e-2)" "unprognostic (5.02e-2)" "unprognostic (3.47e-2)" "unprognostic (7.06e-2)" "unprognostic (4.44e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (6.86e-2)" "unprognostic (3.78e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" 31.4 42.8 20.8 76.7 22.1 59.3 56.0 21.9 28.0 56.6 20.3 119.5 74.5 48.1 51.4 81.3 56.8 55.4 29.0 20.4 21.9 47.9 41.7 41.2 119.7 23.3 21.8 65.7 40.0 62.3 31.6 53.0 23.1 57.6 108.3 18.9 52.1 57.2 15.3 38.0 80.8 46.8 21.8 61.7 84.1 36.2 22.0 103.9 78.4 17.5 123.9 63.7 51.7 23.4 152.5 90.6 57.4 114.7 32.9 39.0 118.7 105.1 117.1 138.0 126.6 168.0 266.3 233.4 190.3 116.9 140.2 173.1 178.1 143.1 151.5 219.3 176.8 161.3 105.7 130.1 77.4 288.1 223.4 70.7 77.0 107.1 70.3 107.7 106.1 298.5 215.2 90.1 61.6 115.7 331.6 161.4 133.2 180.2 229.6 225.0 136.0 104.0 149.5 216.1 44.7 56.6 176.0 117.0 227.9 224.0 137.9 220.6 123.8 91.3 106.2 28.5 261.1 54.4 124.9 319.2 75.3 235.8 121.4 147.5 87.7 200.1 130.0 115.9 107.5 151.6 126.2 140.6 103.0 142.0 143.7 133.6 63.7 144.2 156.4 64.9 142.0 204.6 20.8 22.1 21.9 28.0 20.4 21.9 23.3 21.8 23.1 21.8 22.0 23.4 45.3 25.6 45.4 25.5 82.7 24.9 57.4 99.1 38.7 15.1 35.1 29.1 22.1 61.5 73.4 68.0 16.7 93.1 64.0 142.4 95.9 75.7 20.2 33.7 39.8 56.2 86.3 60.8 1.9 73.6 110.9 25.8 65.2 39.5 30.4 23.6 63.5 28.1 43.6 11.8 8.8 122.8 52.9 38.2 19.0 8.7 41.0 35.0 28.4 16.9 52.7 34.2 69.0 14.6 19.4 92.5 141.5 44.4 38.4 28.5 57.0 30.0 67.3 14.6 59.2 22.8 38.1 72.5 69.8 60.2 25.4 93.4 73.6 102.6 136.0 55.8 HDDC2 "C6orf74, CGI-130, dJ167O5.2" ENSG00000111906 "HD domain containing 2" Q7Z4H3 6 125219962-125302078 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 338.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035677 Approved Approved Nucleoplasm,Nucleoli NA NA 44000 "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA035677: AB_10603768" "unprognostic (8.34e-2)" "unprognostic (5.41e-2)" "unprognostic (6.52e-2)" "unprognostic (6.25e-2)" "unprognostic (2.78e-2)" "unprognostic (6.39e-3)" "unprognostic (1.04e-3)" "unprognostic (1.76e-1)" "unprognostic (2.18e-1)" "unprognostic (2.38e-2)" "unprognostic (8.59e-3)" "unprognostic (5.13e-2)" "unprognostic (4.56e-2)" "unprognostic (2.54e-1)" "unprognostic (3.68e-2)" "unprognostic (1.80e-2)" "unprognostic (9.54e-2)" 47.4 84.4 58.0 20.1 65.9 19.7 42.1 59.5 98.5 47.2 78.4 38.8 20.3 36.2 29.6 49.7 37.0 15.1 82.3 60.8 64.5 75.6 22.9 31.9 27.1 65.1 66.8 41.1 44.5 49.4 50.0 15.7 63.0 38.5 22.1 31.5 45.8 23.8 118.1 39.0 30.6 13.6 60.8 27.6 43.7 58.7 61.6 22.2 40.3 60.7 24.8 39.2 39.5 60.7 29.7 81.2 46.2 191.3 23.0 30.8 59.7 36.4 41.4 30.9 33.1 122.7 30.4 119.9 80.8 57.4 89.0 26.5 53.1 41.1 36.5 46.7 166.8 55.2 43.6 125.1 65.0 76.6 45.3 56.0 61.8 49.6 104.6 44.6 20.2 67.8 205.1 51.4 59.5 162.7 61.2 73.8 57.7 79.9 58.8 92.8 37.2 25.2 68.7 34.1 84.0 44.5 43.9 84.8 88.8 35.4 50.2 126.6 18.2 37.7 44.5 58.8 75.8 72.1 48.2 110.1 56.0 122.6 80.4 13.8 33.4 6.7 53.3 30.6 43.8 71.2 57.7 72.6 36.1 59.4 71.3 78.2 7.3 62.1 29.0 38.3 55.7 44.0 58.0 65.9 59.5 98.5 60.8 64.5 65.1 66.8 63.0 60.8 61.6 60.7 23.0 25.6 41.2 22.5 39.3 44.6 64.3 114.9 70.6 62.6 73.5 114.4 119.9 37.1 55.3 62.5 14.6 86.6 56.0 35.0 338.5 86.0 61.3 50.9 60.7 24.2 64.5 33.4 17.1 98.0 156.4 67.5 33.6 37.5 38.0 84.8 9.3 21.3 112.2 69.0 17.9 76.4 77.3 54.2 20.4 42.1 91.0 34.6 80.0 15.0 31.7 90.5 155.5 19.1 10.6 58.5 45.3 114.7 47.4 101.9 72.3 254.8 38.9 25.0 39.5 83.9 72.6 124.5 74.6 88.6 43.0 45.7 47.6 145.8 84.1 57.9 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 837.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" 72.5 108.1 43.1 21.0 49.6 57.9 66.6 48.0 46.0 54.8 47.3 44.5 242.9 43.8 17.4 42.6 49.9 41.4 58.5 40.9 46.0 69.1 145.8 54.6 28.2 52.5 46.5 80.0 75.9 50.2 27.8 34.6 49.9 42.4 21.7 15.2 43.7 36.8 39.3 59.6 165.7 38.7 49.9 58.5 45.1 29.8 46.8 19.5 122.6 37.7 21.4 51.2 50.3 53.5 74.2 46.2 29.3 54.8 229.6 167.6 20.5 65.0 91.0 60.2 79.7 29.8 26.6 21.2 25.2 128.8 51.9 64.7 37.6 54.2 69.1 3.0 30.0 12.0 51.0 74.2 159.1 22.3 11.3 134.7 47.9 80.7 101.9 187.0 124.3 25.1 13.6 19.4 103.9 48.1 18.3 34.9 42.5 71.5 30.0 40.2 85.3 22.1 50.8 74.1 16.6 14.8 85.6 41.1 86.5 84.2 21.3 33.6 140.2 45.7 53.1 72.6 36.2 16.4 14.4 7.9 73.2 38.5 18.8 15.6 65.7 17.2 9.6 49.4 13.5 11.5 16.5 10.4 51.2 11.8 20.6 12.1 21.0 18.7 69.8 25.3 9.7 25.9 43.1 49.6 48.0 46.0 40.9 46.0 52.5 46.5 49.9 49.9 46.8 53.5 120.1 54.5 21.3 2.0 14.9 37.5 56.2 38.3 39.9 43.0 73.3 95.8 26.7 115.8 19.8 57.0 4.2 36.2 14.5 56.5 99.7 89.5 33.8 8.6 27.4 80.4 20.4 174.4 1.5 100.3 27.1 68.6 28.5 14.6 1.3 31.6 162.4 121.7 82.0 6.7 1.7 45.3 18.3 85.4 43.1 13.0 89.2 53.7 62.2 0.0 78.1 44.2 10.3 4.5 3.5 71.1 90.5 94.0 8.0 79.8 837.6 93.0 7.0 6.7 52.6 35.7 40.8 13.8 7.5 44.5 36.1 26.3 14.5 84.3 93.6 54.3 HIBADH NS5ATP1 ENSG00000106049 "3-hydroxyisobutyrate dehydrogenase" P31937 7 27525442-27662883 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 543.9;Proximal tubular cells: 355.1;Syncytiotrophoblasts: 272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019522, HPA021002" Enhanced NA NA 820000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA019522: AB_1850690, HPA021002: AB_1850692" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "unprognostic (7.50e-2)" "unprognostic (9.79e-2)" "unprognostic (1.72e-1)" "unprognostic (2.28e-3)" "unprognostic (7.22e-3)" "unprognostic (3.14e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (2.05e-2)" "prognostic favorable (5.56e-11)" "unprognostic (2.49e-2)" "unprognostic (5.47e-2)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" 62.1 79.0 15.0 11.9 18.0 7.6 56.5 18.8 18.4 37.2 27.6 33.8 35.0 35.3 11.6 20.4 41.6 28.4 66.7 13.2 18.2 160.5 197.9 20.4 15.1 16.1 17.0 33.4 34.2 97.4 14.1 47.4 16.9 44.7 34.5 31.5 45.4 42.4 117.4 13.1 32.0 37.2 15.6 18.0 34.0 26.4 17.4 21.2 54.5 203.2 14.8 33.5 18.0 17.5 74.0 46.8 31.0 50.1 89.1 109.8 29.3 44.8 83.8 46.3 52.8 27.6 85.2 29.9 38.4 81.4 79.4 67.1 34.5 66.5 67.3 20.9 34.6 14.6 73.0 114.3 73.8 22.4 16.1 101.2 54.1 34.8 120.6 112.1 61.7 35.3 59.7 29.2 117.2 31.2 21.4 34.7 30.0 110.4 56.0 21.2 31.2 33.1 106.5 43.6 28.6 31.7 93.8 173.5 77.9 76.4 75.0 48.6 40.3 28.6 49.5 47.1 31.2 51.8 39.7 17.8 41.2 67.8 85.1 5.3 17.3 8.2 16.7 22.8 22.5 18.2 18.4 19.3 19.3 16.4 24.0 19.8 3.0 22.9 22.0 9.1 13.2 17.4 15.0 18.0 18.8 18.4 13.2 18.2 16.1 17.0 16.9 15.6 17.4 17.5 17.3 9.6 6.4 56.2 14.1 21.3 43.6 51.9 17.1 15.8 58.8 28.2 105.8 58.6 37.7 47.8 4.2 181.1 8.1 23.3 543.9 35.8 58.5 22.8 28.5 21.5 15.6 33.2 64.4 29.1 138.9 44.6 43.3 27.3 2.5 12.0 25.4 149.8 53.7 23.5 85.9 28.9 40.7 28.3 10.0 62.3 44.7 18.5 65.8 51.5 11.0 34.1 8.2 147.2 131.6 28.0 24.1 36.9 20.1 46.1 58.4 355.1 50.8 11.9 46.0 31.6 35.4 35.0 44.3 22.4 15.5 272.4 15.2 77.3 38.8 47.3 HIRA "DGCR1, TUP1, TUPLE1" ENSG00000100084 "Histone cell cycle regulator" P54198 22 19330698-19447450 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.7;Inhibitory neurons: 51.1;Oligodendrocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB039243, CAB039244, HPA050714, HPA052902" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB039243: , CAB039244: , HPA050714: AB_2681219, HPA052902: AB_2681984" "unprognostic (1.32e-1)" "unprognostic (1.74e-3)" "unprognostic (2.45e-3)" "unprognostic (1.11e-1)" "unprognostic (4.59e-2)" "unprognostic (2.46e-1)" "unprognostic (2.42e-2)" "unprognostic (2.17e-2)" "unprognostic (2.50e-1)" "prognostic favorable (8.11e-4)" "prognostic favorable (3.97e-4)" "unprognostic (9.05e-2)" "prognostic favorable (5.18e-6)" "unprognostic (4.84e-2)" "unprognostic (8.57e-2)" "unprognostic (6.36e-2)" "unprognostic (1.32e-3)" 11.2 12.9 16.1 10.6 15.1 26.1 10.2 14.6 15.9 9.4 13.3 14.0 13.9 12.3 6.0 12.4 12.2 7.3 12.9 15.9 14.1 13.8 21.7 10.6 14.2 14.2 15.3 11.2 12.6 22.1 13.2 8.4 13.8 9.3 10.1 7.3 9.9 8.8 23.4 12.5 13.7 9.4 14.0 13.1 14.2 10.1 17.9 20.6 56.1 11.0 11.4 12.2 8.6 14.6 27.0 23.5 32.4 33.7 31.0 20.5 22.5 22.4 25.7 36.1 35.6 53.8 15.4 52.1 10.6 29.0 21.5 30.8 46.4 28.2 23.1 32.1 53.9 48.4 25.5 49.5 33.6 113.1 33.6 24.7 27.1 28.3 27.6 19.4 26.5 51.6 253.1 27.0 20.9 33.7 56.0 40.4 29.6 63.8 23.5 43.7 46.0 15.6 20.9 29.8 47.0 31.2 25.0 25.4 31.7 16.4 16.0 39.0 30.7 24.5 36.0 25.4 26.5 28.4 30.3 53.7 28.7 36.2 20.7 4.8 0.7 3.3 1.3 0.7 1.3 2.4 0.7 1.3 0.9 4.5 0.3 1.0 1.3 2.1 0.4 1.7 0.4 0.8 16.1 15.1 14.6 15.9 15.9 14.1 14.2 15.3 13.8 14.0 17.9 14.6 7.7 6.4 0.5 29.4 7.4 9.2 2.2 4.4 0.6 7.7 6.4 7.4 2.3 2.8 2.3 5.5 2.1 3.8 12.6 11.7 5.9 5.4 6.2 6.8 8.4 5.6 2.4 19.4 49.7 8.9 3.6 4.7 3.1 7.1 0.0 8.7 7.1 21.1 6.6 16.8 51.1 10.5 4.1 9.1 3.8 2.4 5.0 4.9 10.6 38.4 7.9 5.5 14.4 37.7 45.5 7.9 8.4 6.8 4.5 5.0 8.2 9.9 4.2 4.6 6.6 7.7 6.1 12.9 10.3 4.5 10.5 3.0 6.6 9.2 14.2 2.2 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 HMGCL HL ENSG00000117305 "3-hydroxy-3-methylglutaryl-CoA lyase" P35914 1 23801885-23838620 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 322.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.4;Proximal tubular cells: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004727 Enhanced "Intracellular and membrane" NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA004727: AB_1079074" "unprognostic (8.24e-2)" "unprognostic (3.21e-2)" "prognostic favorable (7.67e-4)" "unprognostic (1.23e-3)" "unprognostic (5.47e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (3.05e-1)" "unprognostic (8.24e-2)" "prognostic favorable (5.07e-8)" "unprognostic (1.72e-1)" "unprognostic (2.46e-2)" "unprognostic (8.60e-2)" "unprognostic (3.39e-3)" 27.5 63.0 26.3 16.8 27.5 7.5 25.8 27.5 28.3 27.5 33.0 53.3 45.7 20.2 47.2 32.8 35.6 26.3 42.5 24.6 26.9 115.5 322.5 23.6 21.7 28.0 26.2 21.6 33.4 60.2 26.3 19.9 27.7 31.7 52.9 16.1 30.3 27.9 63.7 25.5 40.0 23.3 27.4 26.8 40.9 17.9 30.1 23.4 40.5 70.2 25.1 28.6 24.2 29.6 28.5 16.0 17.7 13.4 70.6 53.5 6.8 22.0 38.3 23.3 28.2 10.2 53.7 14.8 44.3 34.6 19.0 22.4 21.3 35.7 25.2 30.4 16.1 19.8 13.8 23.5 90.9 7.8 12.7 62.4 52.0 30.8 58.5 62.5 32.2 27.4 20.6 20.3 43.3 29.3 12.2 15.3 4.6 77.4 22.1 17.2 14.5 27.9 55.4 14.5 14.8 13.2 28.6 10.8 49.3 23.3 33.9 19.3 24.3 19.3 11.6 35.5 9.7 28.7 15.2 13.3 47.7 28.7 23.0 103.5 67.0 66.0 36.3 66.0 39.8 45.9 39.1 42.1 58.0 51.2 39.6 37.7 25.5 54.4 77.5 43.9 45.5 61.7 26.3 27.5 27.5 28.3 24.6 26.9 28.0 26.2 27.7 27.4 30.1 29.6 19.9 12.8 25.7 14.0 16.3 5.9 29.9 54.3 9.6 24.6 19.9 17.1 33.7 41.5 30.6 49.7 18.8 43.0 10.0 48.1 119.3 57.7 2.3 25.0 17.5 22.5 9.0 18.7 4.3 24.0 27.3 20.8 30.5 23.1 17.7 29.7 30.4 172.4 61.6 35.3 5.3 49.5 28.5 23.5 7.7 3.6 21.8 23.5 21.4 8.4 41.4 37.1 24.7 6.0 12.5 31.2 53.8 24.5 8.3 29.4 70.9 216.8 31.5 25.5 6.6 17.1 21.6 6.6 5.4 13.8 6.5 41.3 15.2 65.6 48.9 24.3 HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.6;lymphoid tissue: 27.3;testis: 27.5" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Erythroid cells: 133.3;Extravillous trophoblasts: 55.1;Late spermatids: 60.9;Spermatocytes: 100.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "Centrosome, Cytosol" "CAB002433: AB_564080, HPA040025: AB_2676805, HPA043926: , HPA061524: AB_2684551" "unprognostic (3.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.38e-3)" "unprognostic (8.88e-3)" "unprognostic (2.12e-1)" "prognostic unfavorable (5.52e-4)" "prognostic unfavorable (1.93e-7)" "prognostic unfavorable (1.09e-4)" "unprognostic (5.68e-2)" "unprognostic (2.50e-1)" "prognostic unfavorable (3.71e-5)" "unprognostic (1.02e-1)" "unprognostic (0.00e+0)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-2)" 0.8 0.7 0.2 10.1 0.3 20.6 2.1 0.3 0.4 1.1 0.1 6.6 7.4 0.8 0.2 4.0 0.5 0.9 0.8 0.2 0.2 0.7 1.7 0.9 18.1 0.5 0.3 0.2 0.3 0.9 0.2 6.2 0.4 0.5 8.8 0.8 0.8 0.2 1.2 4.2 6.5 2.9 0.3 2.9 3.6 27.5 0.7 27.3 0.7 0.4 17.7 2.2 1.4 0.5 77.0 47.2 94.5 50.8 5.0 9.0 70.3 71.4 34.9 88.0 78.9 96.8 145.1 127.5 66.0 22.2 118.5 86.3 112.4 69.0 148.6 116.1 34.4 76.7 32.3 48.4 1.4 68.7 67.3 2.4 4.1 82.8 64.0 14.7 50.6 85.7 73.2 101.0 93.2 28.5 72.3 38.8 81.9 51.2 51.6 78.0 126.3 63.9 34.8 20.4 78.8 43.8 106.3 32.8 38.6 45.1 97.3 54.5 32.9 63.2 52.4 50.6 97.2 53.7 96.3 102.4 41.4 104.2 61.1 0.2 0.2 0.0 0.1 0.1 0.3 0.3 0.3 0.1 0.2 0.2 0.1 0.2 0.1 0.5 0.0 0.6 1.5 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.5 0.3 0.4 0.3 0.7 0.5 0.4 0.0 1.1 1.3 6.0 2.5 1.8 4.5 2.8 0.6 3.2 3.7 2.5 4.3 3.2 0.0 0.0 37.3 2.3 5.3 0.0 0.8 86.2 3.8 3.1 3.1 1.2 133.3 0.6 0.2 55.1 4.6 11.7 5.7 0.0 21.6 5.3 3.8 22.2 0.0 0.4 7.8 6.1 8.8 2.7 60.9 2.1 7.6 0.0 0.0 2.3 0.1 1.0 0.5 1.2 0.2 0.3 0.7 22.9 1.5 1.3 2.6 2.8 1.0 6.6 0.6 3.8 100.9 23.3 14.1 1.4 4.5 5.2 1.6 15.6 3.0 HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 34.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 440.0;Inhibitory neurons: 112.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB004437: AB_627742, HPA036521: AB_2675170, HPA036522: AB_2675171" "unprognostic (2.80e-1)" "unprognostic (5.30e-2)" "unprognostic (4.00e-2)" "unprognostic (5.79e-2)" "unprognostic (8.83e-2)" "unprognostic (6.40e-2)" "unprognostic (2.00e-3)" "unprognostic (2.41e-3)" "unprognostic (2.22e-1)" "unprognostic (3.79e-1)" "unprognostic (3.07e-3)" "unprognostic (3.98e-1)" "unprognostic (7.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.72e-1)" "unprognostic (2.83e-2)" "unprognostic (2.86e-3)" 2.8 1.3 2.1 2.3 14.0 0.3 2.5 10.6 27.6 3.9 0.0 1.2 0.7 6.7 4.1 4.6 1.7 6.8 20.5 17.9 5.6 5.8 1.7 5.1 1.1 0.0 3.3 3.8 2.2 4.1 2.3 5.4 2.2 1.7 1.0 5.8 1.2 1.7 34.0 2.4 0.8 4.7 0.6 0.8 2.0 5.3 7.4 1.3 15.0 12.9 1.4 8.0 1.7 15.1 14.6 9.8 14.5 23.1 5.4 3.6 33.5 9.0 7.2 9.0 9.6 15.5 9.9 0.2 26.9 7.8 16.2 7.7 18.2 24.5 15.4 2.2 14.3 17.3 3.9 15.7 8.8 8.3 5.4 5.8 15.4 8.1 22.4 3.6 4.3 26.4 21.7 9.3 11.7 20.4 34.8 5.7 24.5 5.2 8.4 22.4 23.8 22.2 9.6 22.3 14.7 8.8 17.2 12.0 9.3 16.0 16.5 7.2 0.7 6.6 16.7 8.0 16.1 4.5 10.8 8.5 18.8 3.3 13.0 0.0 0.0 0.0 0.4 0.0 0.2 0.4 0.1 0.1 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.1 2.1 14.0 10.6 27.6 17.9 5.6 0.0 3.3 2.2 0.6 7.4 15.1 4.3 51.3 9.6 21.9 12.1 64.2 28.0 8.5 20.5 24.4 25.6 18.2 95.2 7.2 12.1 16.5 27.1 58.4 20.3 4.3 11.7 4.8 4.7 30.6 24.9 9.5 11.4 0.4 440.0 4.3 44.8 19.3 5.6 39.9 5.7 16.9 4.6 6.9 11.9 52.2 112.1 7.5 10.2 9.6 29.7 5.5 5.6 13.9 21.4 31.9 3.0 4.4 8.2 86.0 19.3 5.5 2.7 8.6 8.9 23.3 3.1 7.0 10.8 8.1 13.1 29.7 19.3 6.9 10.3 23.9 54.8 84.4 9.8 10.2 3.0 25.2 HOXB8 "HOX2, HOX2D" ENSG00000120068 "Homeobox B8" P17481 17 48611377-48615292 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.1;epididymis: 48.1;kidney: 37.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 88.3;Distal tubular cells: 72.4;Endometrial ciliated cells: 21.3;Enteroendocrine cells: 44.1;Glandular and luminal cells: 26.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 33.3" "Region enhanced" "Detected in many" "spinal cord: 114.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.0;HDLM-2: 17.2;HEK 293: 36.9;LHCN-M2: 17.3;RPTEC TERT1: 35.3" "Region enriched" "Detected in single" 65 "pons and medulla: 6.5" "Region enriched" "Detected in all" 5 "spinal cord: 51.2" HPA075905 Supported Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA075905: AB_2686767" "unprognostic (4.44e-1)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-2)" "unprognostic (9.07e-5)" "unprognostic (6.63e-3)" "unprognostic (1.40e-3)" "unprognostic (6.00e-2)" "unprognostic (5.66e-3)" "unprognostic (2.93e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.30e-7)" "unprognostic (1.77e-2)" "unprognostic (6.64e-2)" "unprognostic (4.57e-2)" "unprognostic (2.88e-3)" 7.2 7.2 0.1 1.5 0.0 0.0 2.7 0.0 0.0 10.7 0.0 4.7 0.0 2.8 48.1 0.0 1.4 0.0 0.0 0.0 0.0 37.6 0.0 0.4 0.0 36.4 0.0 0.1 0.1 0.8 0.1 0.3 1.8 1.0 1.2 0.0 0.0 20.8 0.4 0.5 7.1 1.5 114.1 0.1 6.6 1.0 0.0 0.0 0.1 0.0 0.0 3.7 0.7 20.8 2.1 5.3 0.0 0.8 0.7 1.0 0.8 0.0 0.0 0.0 0.0 0.3 0.8 0.0 34.0 5.3 0.6 0.0 0.1 0.0 0.0 17.2 36.9 1.0 0.1 0.0 0.3 0.0 5.5 1.1 0.0 0.1 0.0 0.7 2.1 0.2 11.6 0.0 17.3 0.0 0.0 0.4 0.0 11.3 0.0 0.0 3.6 0.1 35.3 1.0 0.0 0.1 0.6 0.0 5.4 0.1 0.4 0.0 8.8 0.0 1.6 0.1 0.7 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 36.4 0.0 1.8 114.1 0.0 20.8 4.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 88.3 0.0 0.0 0.1 1.8 72.4 0.0 0.3 21.3 2.1 2.6 44.1 0.0 0.0 0.0 0.8 0.3 0.0 26.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.2 0.0 0.0 0.7 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.2 2.7 8.9 0.0 0.0 0.0 0.1 0.8 2.3 9.2 0.0 0.0 0.0 0.3 0.0 5.0 0.0 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 HSBP1 ENSG00000230989 "Heat shock factor binding protein 1" O75506 16 83807978-83819737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (3.27e-2)" "unprognostic (9.23e-2)" "unprognostic (2.22e-1)" "prognostic favorable (5.73e-4)" "unprognostic (1.85e-2)" "unprognostic (3.74e-3)" "unprognostic (1.03e-2)" "unprognostic (3.07e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.96e-4)" "unprognostic (2.00e-1)" "unprognostic (3.00e-1)" "unprognostic (2.84e-3)" "unprognostic (4.39e-2)" "unprognostic (9.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.70e-2)" 19.6 34.4 34.3 20.5 33.9 12.6 18.7 35.3 39.4 20.4 36.1 20.9 24.9 16.0 12.2 40.4 19.3 8.4 38.4 33.1 37.4 35.2 19.1 18.2 10.3 36.3 34.9 21.6 18.9 32.4 21.8 18.7 36.4 16.6 15.2 21.9 29.7 10.8 40.7 12.5 22.2 13.0 37.2 17.1 21.8 32.9 36.8 19.5 25.1 32.1 14.9 21.1 21.0 38.5 69.1 91.8 124.6 57.5 50.5 44.7 57.9 97.5 47.4 67.6 31.6 77.4 65.7 46.7 96.9 80.3 65.8 66.2 88.3 64.3 60.3 16.8 101.5 35.8 70.9 105.8 41.6 54.3 58.2 44.7 47.1 72.0 39.7 58.1 43.4 35.1 87.8 13.7 52.0 173.4 44.2 65.1 103.8 76.9 67.5 59.7 94.3 22.6 104.4 62.4 85.6 79.7 166.5 34.5 46.9 63.6 119.1 62.9 75.8 86.1 69.8 55.0 70.4 44.6 52.6 186.3 67.5 63.6 96.1 60.9 118.0 158.5 23.4 159.9 25.8 69.1 28.5 26.7 96.2 48.6 26.0 25.0 157.1 31.4 158.1 71.9 43.7 132.7 34.3 33.9 35.3 39.4 33.1 37.4 36.3 34.9 36.4 37.2 36.8 38.5 159.3 157.0 124.8 21.5 79.9 194.6 236.1 694.7 157.1 89.1 239.1 250.3 712.8 140.2 465.6 252.0 20.9 391.1 76.7 233.9 659.3 410.6 364.4 484.6 161.7 183.1 238.9 78.0 16.0 335.7 482.0 231.5 116.2 202.1 68.5 214.2 141.7 161.2 427.1 109.4 23.8 274.7 547.3 223.2 177.0 241.1 219.6 260.9 304.1 15.0 242.4 236.9 76.2 17.6 33.7 440.2 291.0 143.0 90.8 318.7 259.7 562.7 858.5 90.3 118.3 154.1 220.4 685.0 243.5 279.3 207.7 285.4 58.9 282.5 234.4 376.1 HTATSF1 TAT-SF1 ENSG00000102241 "HIV-1 Tat specific factor 1" O43719 X 136497079-136512346 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 173.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000504 Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA000504: AB_10752094" "unprognostic (3.56e-2)" "prognostic favorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (6.72e-2)" "unprognostic (3.70e-1)" "unprognostic (3.32e-3)" "unprognostic (3.27e-1)" "unprognostic (2.09e-2)" "unprognostic (1.49e-1)" "unprognostic (1.73e-2)" "unprognostic (3.37e-2)" "prognostic favorable (8.13e-8)" "unprognostic (7.12e-2)" "unprognostic (2.67e-2)" "unprognostic (2.25e-2)" "unprognostic (4.05e-1)" 38.9 99.7 53.4 31.0 54.1 54.7 35.7 56.0 60.6 33.5 45.9 34.8 25.4 39.4 59.1 30.3 35.1 28.6 65.4 51.5 74.1 43.3 30.8 26.9 34.5 60.8 56.4 60.2 27.7 52.8 144.7 36.4 56.7 35.3 35.3 56.1 28.4 39.6 181.8 35.1 26.0 34.6 56.1 28.5 32.5 41.5 79.9 43.0 47.6 109.2 35.7 35.1 27.8 55.3 151.4 79.3 99.9 70.5 72.1 54.0 87.1 71.5 60.4 57.2 55.5 47.6 66.0 114.1 163.1 68.1 66.3 66.0 120.5 52.3 75.0 86.5 106.9 70.9 99.9 59.2 40.8 138.1 57.7 48.4 66.1 63.2 39.3 40.8 60.3 166.3 67.4 81.0 76.5 114.3 135.7 115.4 58.7 139.4 115.7 104.2 123.7 103.3 62.0 105.9 69.0 106.9 66.7 54.4 56.4 83.9 39.8 96.5 57.4 69.2 52.2 79.5 126.1 47.6 69.1 92.7 44.4 192.4 50.3 48.4 20.6 33.2 41.0 21.5 44.5 33.9 44.4 42.2 28.5 33.3 44.8 40.7 6.7 49.7 35.3 20.6 47.9 27.9 53.4 54.1 56.0 60.6 51.5 74.1 60.8 56.4 56.7 56.1 79.9 55.3 28.2 51.3 42.9 11.4 36.8 29.6 38.0 28.0 38.7 52.5 25.8 23.5 173.3 20.0 53.1 49.7 10.4 95.3 37.6 26.2 49.0 36.7 6.8 51.0 39.3 29.8 81.2 55.5 10.2 34.3 69.8 42.1 42.3 32.9 34.8 48.4 10.4 22.8 38.2 42.1 12.1 37.8 28.5 19.5 19.2 11.7 45.1 30.3 32.0 7.5 34.4 78.0 25.7 8.0 13.6 32.5 18.5 53.8 54.3 37.2 20.4 32.1 44.4 56.7 46.0 46.9 41.0 29.4 92.2 42.7 26.6 116.8 51.6 45.8 32.6 36.8 HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155087392 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.6" "Group enriched" "Detected in some" 4 "Early spermatids: 8.7;Excitatory neurons: 7.6;Inhibitory neurons: 10.0;Late spermatids: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB017467 Approved NA NA "Cluster 6: Brain - Smell perception" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB017467: AB_2122566" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" 0.0 0.0 1.7 0.0 1.6 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.6 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 3.6 2.8 1.3 1.6 0.6 2.7 1.8 0.2 1.2 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ID4 bHLHb27 ENSG00000172201 "Inhibitor of DNA binding 4, HLH protein" P47928 6 19837370-19842197 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 274.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 246.6;Endometrial ciliated cells: 438.4;Endometrial stromal cells: 362.6;Glandular and luminal cells: 335.3;Muller glia cells: 391.8;Smooth muscle cells: 368.8" "Cancer enhanced" "Detected in all" "thyroid cancer: 111.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 45.0;AN3-CA: 50.7;EFO-21: 105.1;HEK 293: 66.0;SCLC-21H: 117.0;SuSa: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075639 Supported Nucleoplasm NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA075639: " "unprognostic (3.25e-3)" "unprognostic (7.37e-3)" "unprognostic (1.80e-1)" "unprognostic (6.34e-3)" "unprognostic (4.17e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" "prognostic favorable (2.49e-4)" "unprognostic (7.26e-2)" "unprognostic (1.66e-3)" "unprognostic (2.41e-2)" "unprognostic (3.13e-2)" "unprognostic (1.03e-3)" "unprognostic (2.57e-3)" 74.6 5.0 50.1 7.5 47.6 0.2 41.7 33.6 55.4 41.0 22.8 9.8 7.2 30.0 9.4 21.7 70.3 10.2 75.7 48.0 59.6 30.8 4.4 27.8 5.0 42.8 60.8 48.4 19.1 2.5 36.4 22.2 42.2 29.7 6.7 19.4 27.1 44.0 3.6 107.8 11.9 21.0 43.6 20.2 19.8 23.0 58.5 2.0 274.7 3.1 2.1 31.4 33.1 40.2 0.0 0.6 45.0 50.7 1.2 0.1 0.1 5.8 0.1 0.4 0.0 0.0 0.0 0.0 105.1 14.1 0.2 20.3 0.0 0.0 0.4 0.0 66.0 0.0 0.0 0.5 0.3 0.0 0.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 8.1 6.3 0.0 0.0 0.0 0.2 7.6 14.2 117.0 1.5 0.0 1.8 7.2 37.6 3.2 0.0 0.0 0.2 5.6 0.1 1.6 0.0 0.1 1.1 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.1 47.6 33.6 55.4 48.0 59.6 42.8 60.8 42.2 43.6 58.5 40.2 31.8 96.1 53.0 229.9 1.9 83.1 190.8 16.7 232.8 11.2 143.8 246.6 42.5 7.2 19.6 68.0 2.1 9.9 2.9 15.6 50.9 18.0 2.1 438.4 362.6 19.9 91.6 0.0 1.8 3.3 9.5 83.9 118.3 335.3 0.0 17.6 23.9 0.0 2.7 3.3 1.2 23.4 22.4 0.6 24.8 7.9 8.1 5.3 88.9 2.8 0.0 391.8 0.0 0.5 0.3 1.4 27.1 0.0 1.4 93.6 8.2 76.0 8.4 13.7 0.0 76.3 368.8 1.2 44.9 119.6 78.6 5.9 6.1 0.7 7.8 42.4 IFT22 "DKFZp761N0823, FAP9, FLJ13225, FLJ14117, RABL5" ENSG00000128581 "Intraflagellar transport 22" Q9H7X7 7 101310914-101321823 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 577.5;Late spermatids: 1478.7;Spermatocytes: 357.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 92.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042930 Approved Approved Microtubules,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" "Microtubules, Cytosol" "HPA042930: AB_10794537" "unprognostic (1.55e-2)" "unprognostic (7.22e-2)" "unprognostic (1.29e-1)" "unprognostic (2.23e-2)" "unprognostic (6.70e-3)" "unprognostic (1.03e-1)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (9.99e-2)" "unprognostic (1.73e-2)" "unprognostic (3.39e-2)" "unprognostic (1.15e-2)" "unprognostic (2.23e-2)" "unprognostic (2.63e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" 12.4 22.1 20.2 3.7 21.4 2.8 14.3 19.1 25.7 18.6 27.2 22.1 2.8 21.1 22.9 8.5 27.8 12.1 24.0 21.4 21.7 35.5 7.8 13.1 4.0 20.0 21.1 19.5 18.4 29.9 31.1 2.8 20.2 18.0 3.4 41.4 14.7 6.4 26.3 10.1 7.5 5.8 20.7 4.7 14.9 76.4 21.2 10.1 24.4 19.6 3.6 17.2 11.5 19.9 26.1 38.6 20.7 47.9 17.1 14.5 4.6 8.6 4.8 10.6 7.9 15.4 19.3 3.1 22.1 17.8 41.1 16.6 12.2 12.7 8.2 6.2 16.4 0.6 16.4 15.8 12.6 8.7 4.9 14.9 10.9 25.2 5.9 36.5 10.4 18.2 11.2 3.4 12.6 92.5 15.6 16.3 21.6 19.5 17.4 14.4 13.1 5.3 20.1 15.8 22.3 37.0 25.3 21.0 13.7 33.5 16.3 6.6 10.6 33.1 24.6 64.0 18.0 3.1 10.3 7.5 21.7 2.5 17.3 1.4 0.8 0.9 4.0 1.7 3.8 7.5 4.8 3.6 1.6 5.9 4.3 4.4 1.1 5.8 3.3 4.7 2.0 2.3 20.2 21.4 19.1 25.7 21.4 21.7 20.0 21.1 20.2 20.7 21.2 19.9 12.0 25.6 14.3 6.5 11.9 0.0 25.1 0.0 22.2 26.6 35.5 54.4 42.9 55.8 19.2 49.7 54.2 19.7 2.3 4.0 138.9 73.9 577.5 176.0 32.1 17.0 18.5 17.4 7.2 36.9 17.3 28.3 12.8 28.0 9.5 37.9 21.8 10.7 17.7 32.0 5.3 13.1 0.0 2.7 0.0 1478.7 37.9 6.9 0.0 2.8 2.9 76.2 3.1 3.0 2.4 29.9 13.5 41.3 4.8 17.1 2.9 170.2 102.7 103.9 13.1 21.8 22.6 357.7 71.5 15.0 0.0 6.6 7.3 36.0 8.0 20.4 IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 1675.3;Late spermatids: 2795.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 41.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035514, HPA035515" Supported Approved "Nuclear speckles,Mitochondria,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "Nuclear speckles" "Mitochondria, Cytosol" "HPA035514: AB_10601757, HPA035515: AB_10696505" "unprognostic (1.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (6.96e-5)" "unprognostic (2.98e-2)" "unprognostic (5.46e-3)" "unprognostic (1.02e-2)" "unprognostic (3.79e-2)" "unprognostic (3.61e-3)" "unprognostic (3.59e-2)" "prognostic favorable (7.63e-4)" "unprognostic (5.04e-2)" "unprognostic (2.78e-1)" "unprognostic (1.68e-3)" "unprognostic (1.86e-1)" "unprognostic (4.70e-2)" "unprognostic (8.67e-3)" "unprognostic (6.12e-2)" 8.9 15.3 11.6 8.6 11.7 13.2 13.1 10.2 15.5 11.7 14.8 13.3 6.0 13.3 45.1 8.5 32.0 13.4 10.4 11.4 11.5 21.3 4.5 40.7 17.3 12.0 12.2 14.0 13.8 23.0 16.3 7.8 11.6 27.5 14.6 24.0 9.1 17.5 4.2 8.6 9.0 10.6 11.9 12.1 9.8 42.8 12.0 8.2 26.1 4.4 16.4 13.9 8.3 11.8 35.5 17.2 12.8 23.1 26.1 26.9 7.1 10.6 25.8 15.3 13.6 12.4 6.1 39.5 13.3 17.8 22.0 13.9 11.5 17.8 25.8 6.2 12.2 13.6 8.0 3.3 19.4 28.5 30.2 16.3 16.1 19.9 34.2 24.4 17.5 6.6 6.4 6.9 17.8 18.9 9.5 25.8 13.6 2.7 21.0 6.1 11.5 6.3 31.6 12.3 21.1 14.7 15.9 5.2 9.9 7.1 11.0 8.3 7.5 19.6 10.2 10.5 12.6 8.1 6.2 20.7 28.4 2.7 7.3 0.2 3.5 3.1 3.6 6.5 5.8 41.9 7.4 4.5 10.2 34.9 6.2 3.7 1.8 6.8 12.8 2.0 5.1 4.9 11.6 11.7 10.2 15.5 11.4 11.5 12.0 12.2 11.6 11.9 12.0 11.8 36.6 471.1 291.2 18.6 98.4 41.0 114.1 72.9 34.7 25.6 42.2 50.9 33.8 58.6 201.9 51.5 68.8 22.3 16.9 51.1 117.4 158.8 1675.3 266.3 57.8 38.2 57.2 13.7 52.6 134.1 19.3 78.9 25.5 37.0 44.3 57.1 25.7 5.9 14.5 28.6 20.3 35.7 42.7 8.1 27.7 2795.4 65.3 19.3 46.2 4.7 13.1 56.8 8.2 13.0 13.5 79.4 36.6 64.3 40.2 151.4 24.3 124.5 528.7 72.7 52.6 61.7 61.3 242.2 43.6 25.4 37.2 14.9 30.2 104.9 52.3 93.0 IFTAP "C11orf74, FLJ38678, HEPIS, NWC" ENSG00000166352 "Intraflagellar transport associated protein" Q86VG3 11 36594369-36675695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 10.0;Cardiomyocytes: 60.7;Cytotrophoblasts: 19.3;Extravillous trophoblasts: 19.0;Fibroblasts: 8.5;Hofbauer cells: 26.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044880 Uncertain Approved Aggresome,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Aggresome, Cytosol" "HPA044880: AB_10796908" "unprognostic (9.22e-3)" "unprognostic (6.79e-2)" "unprognostic (3.23e-2)" "unprognostic (7.47e-2)" "unprognostic (5.00e-3)" "unprognostic (1.13e-2)" "unprognostic (1.13e-2)" "unprognostic (9.86e-2)" "unprognostic (2.36e-1)" "unprognostic (3.65e-2)" "unprognostic (8.52e-2)" "unprognostic (1.92e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" "unprognostic (1.17e-2)" "unprognostic (1.24e-1)" "unprognostic (3.24e-1)" 17.1 20.0 19.5 5.3 20.0 13.3 15.3 19.7 31.0 17.0 33.0 30.7 7.5 16.2 23.7 9.5 31.7 12.7 45.3 19.7 19.1 25.3 18.7 11.8 5.4 19.3 20.0 21.8 18.0 16.5 25.9 10.3 19.4 12.8 10.4 19.5 12.2 10.3 41.0 7.2 10.1 16.5 18.9 8.3 17.5 52.4 19.8 10.5 82.2 42.3 5.0 17.5 12.9 20.1 11.4 19.7 41.4 31.3 39.0 56.2 16.4 24.5 26.8 23.6 43.3 0.7 18.8 0.2 18.1 25.0 32.4 4.5 28.3 33.9 48.8 0.2 47.8 19.9 9.2 20.0 30.0 27.4 4.5 36.4 24.4 15.7 22.4 40.5 40.4 15.2 25.4 0.3 25.6 18.8 4.9 22.7 24.8 7.0 31.0 19.5 51.4 11.3 34.1 3.6 0.6 46.6 28.0 5.4 42.6 37.4 38.3 14.7 24.7 32.3 22.3 43.4 21.8 6.2 12.3 0.0 29.4 33.2 17.0 10.5 18.3 1.2 1.6 15.4 5.1 0.0 4.8 3.9 20.9 0.3 11.6 2.9 1.0 14.1 15.3 28.5 0.7 8.3 19.5 20.0 19.7 31.0 19.7 19.1 19.3 20.0 19.4 18.9 19.8 20.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 0.0 0.0 0.0 19.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 19.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 IGHA1 ENSG00000211895 "Immunoglobulin heavy constant alpha 1" P01876 14 105703995-105708665 "Disease related genes, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 7411.2;lymphoid tissue: 6397.6;salivary gland: 8904.9;stomach 1: 6664.9" "Group enriched" "Detected in many" 10 "B-cells: 17763.5;Plasma cells: 34095.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 203 "memory B-cell: 2571.8;naive B-cell: 1114.6" "Lineage enriched" "Detected in many" 284 "B-cells: 2571.8" "Cell line enhanced" "Detected in many" "HDLM-2: 17.4;RPMI-8226: 34.7;SH-SY5Y: 22.3;U-266/70: 78.2;U-266/84: 24.0" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 130000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (8.87e-5)" "unprognostic (5.36e-3)" "unprognostic (2.10e-2)" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "prognostic favorable (3.81e-5)" "unprognostic (1.17e-1)" "unprognostic (3.86e-1)" "unprognostic (2.62e-1)" "unprognostic (3.26e-2)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.83e-7)" "unprognostic (8.10e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (2.99e-2)" 200.6 41.7 1.4 1121.1 1.0 918.5 953.5 0.7 6.5 214.3 4.2 5973.6 7411.2 79.9 3.5 641.9 203.5 662.9 73.8 0.6 1.3 278.5 327.7 1305.3 1420.6 3.5 1.1 40.6 115.1 3.5 38.3 6.7 1.1 202.5 1338.5 0.0 8904.9 69.0 10.8 56.7 3788.8 69.5 1.4 6397.6 6664.9 23.2 1.0 131.0 447.3 0.4 1949.0 1616.2 302.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.8 0.0 0.0 3.6 0.0 0.0 0.0 17.4 0.0 3.7 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.1 0.0 0.0 4.1 14.4 5.5 0.0 0.0 3.8 4.3 34.7 0.0 0.0 9.7 22.3 2.6 0.0 0.0 0.0 0.0 1.6 5.1 0.0 3.9 4.2 3.2 78.2 24.0 2.2 0.0 2.4 0.0 3.8 3.0 0.6 1.3 0.3 1.0 2571.8 0.7 1.1 1.5 1114.6 0.4 1.0 9.0 0.9 0.9 1.7 1.0 508.3 1.4 1.0 0.7 6.5 0.6 1.3 3.5 1.1 1.1 1.4 1.0 1.9 11.8 131.4 783.5 0.0 17763.5 0.0 26.0 0.0 1.2 0.0 22.4 4.6 4.7 22.8 46.4 0.0 0.0 0.7 55.5 20.8 0.0 0.0 0.0 0.1 0.1 26.5 28.4 167.0 0.0 0.0 0.5 56.5 99.4 0.1 584.8 0.0 353.8 225.1 1.6 0.0 0.0 13.6 0.0 57.8 0.0 0.0 0.0 34.6 0.0 0.0 6.7 0.0 11.3 0.0 0.0 0.0 12.8 0.0 34095.8 33.2 0.0 1.4 16.0 0.0 0.0 2.0 13.6 0.0 0.0 0.8 0.0 6.0 2514.2 0.0 27.9 1.2 IGHA2 ENSG00000211890 "Immunoglobulin heavy constant alpha 2 (A2m marker)" P01877 14 105583731-105588395 "Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 5017.7;salivary gland: 3728.4" "Group enriched" "Detected in many" 22 "B-cells: 3713.4;Plasma cells: 10918.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 876 "memory B-cell: 279.6;naive B-cell: 123.8" "Lineage enriched" "Detected in single" 1214 "B-cells: 279.6" "Group enriched" "Detected in some" 42 "U-266/70: 181.9;U-266/84: 63.9" "Not detected" "Not detected" "HPA001217, HPA006013" Approved "Immunoglobulin genes" NA NA 67000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001217: AB_1079120, HPA006013: AB_1079119" "prognostic favorable (1.98e-9)" "unprognostic (3.20e-2)" "unprognostic (2.23e-2)" "unprognostic (1.53e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.40e-5)" "unprognostic (4.56e-2)" "unprognostic (2.59e-1)" "unprognostic (3.17e-1)" "unprognostic (3.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.50e-6)" "unprognostic (2.12e-1)" "unprognostic (3.28e-2)" "unprognostic (9.70e-2)" "unprognostic (4.47e-1)" 24.3 3.7 0.0 14.2 0.0 12.4 329.7 0.0 0.0 47.6 0.0 5017.7 15.3 8.9 0.0 219.7 35.0 0.9 4.8 0.0 0.0 49.7 35.1 134.2 6.8 0.0 0.0 5.3 30.3 0.0 4.9 0.3 0.0 37.7 8.8 0.0 3728.4 0.1 2.1 17.8 2261.3 1.0 0.0 700.9 670.1 1.1 0.0 22.4 59.8 0.0 13.0 93.4 67.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 2.8 2.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.9 181.9 63.9 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 279.6 0.0 0.1 0.1 123.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.2 12.4 0.0 3713.4 0.0 2.4 0.0 2.8 0.0 1.4 0.3 1.2 5.7 0.6 0.0 0.0 0.1 3.2 3.7 0.0 0.0 0.0 0.0 0.0 15.6 8.5 56.2 0.0 0.0 0.0 8.0 10.7 0.0 15.2 0.0 78.9 6.0 0.3 0.0 0.0 2.9 0.0 10.8 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.0 10918.5 0.3 0.0 0.1 0.0 0.0 0.0 0.1 23.6 0.0 0.0 12.3 0.0 0.4 325.4 0.0 4.8 0.2 IGHG1 ENSG00000211896 "Immunoglobulin heavy constant gamma 1 (G1m marker)" P01857 14 105736343-105743071 "Disease related genes, FDA approved drug targets, Immunoglobulin genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 11451.9;urinary bladder: 3998.0" "Group enriched" "Detected in many" 16 "B-cells: 3900.5;Plasma cells: 9883.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.7" "Immune cell enriched" "Detected in some" 6 "memory B-cell: 766.8" "Lineage enriched" "Detected in many" 123 "B-cells: 766.8" "Group enriched" "Detected in many" 9 "Karpas-707: 157.8;U-698: 392.7" "HPA001245, CAB008642" Supported "Immunoglobulin genes" NA NA 230000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB008642: AB_1617595, HPA001245: AB_1079121" "unprognostic (6.47e-3)" "unprognostic (4.39e-3)" "unprognostic (2.91e-2)" "unprognostic (2.32e-3)" "unprognostic (1.55e-2)" "prognostic favorable (2.67e-4)" "unprognostic (3.90e-2)" "unprognostic (3.25e-1)" "unprognostic (7.52e-2)" "unprognostic (5.36e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.49e-9)" "unprognostic (3.12e-1)" "unprognostic (3.52e-1)" "unprognostic (8.96e-2)" "unprognostic (7.61e-2)" 526.0 696.8 0.7 1661.1 0.6 681.1 203.2 0.5 4.5 518.2 2.8 302.1 103.7 210.6 18.4 334.4 661.5 312.9 143.2 0.4 2.2 491.7 356.1 962.4 3281.1 4.7 3.2 407.0 38.5 7.9 35.8 2.3 2.3 209.8 85.1 0.3 391.6 250.8 13.1 28.5 1008.8 27.6 12.7 11451.9 608.9 172.8 1.2 1773.7 1277.9 0.1 5826.8 3998.0 267.2 1.8 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.7 0.0 0.0 2.3 0.0 0.0 0.0 8.4 0.0 5.3 0.0 0.0 0.0 22.6 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 157.8 0.0 0.0 1.7 2.1 2.6 0.0 0.0 2.9 15.1 3.7 0.0 0.0 18.2 17.0 3.1 0.0 0.0 0.0 0.0 0.2 10.8 0.0 3.2 3.3 4.5 4.9 0.3 392.7 0.1 3.7 0.0 0.2 0.3 0.1 0.3 0.0 0.2 766.8 0.6 0.3 0.4 134.9 0.0 0.1 6.2 0.1 0.1 0.1 0.2 96.2 0.7 0.6 0.5 4.5 0.4 2.2 4.7 3.2 2.3 12.7 1.2 1.8 2.9 73.7 378.5 0.0 3900.5 0.0 8.1 0.0 0.0 0.0 0.5 0.0 2.8 22.8 9.3 0.0 0.0 0.0 0.4 7.0 0.0 0.0 0.5 0.0 0.1 8.5 13.9 83.4 0.0 0.0 0.0 13.6 8.2 0.0 209.4 0.0 46.1 52.9 0.1 0.0 0.0 5.0 0.0 62.8 0.0 0.9 0.0 9.7 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 5.4 0.0 9883.3 9.1 0.0 10.9 1.5 0.1 0.0 0.0 1.5 1.9 1.0 0.0 0.0 0.0 415.6 0.0 13.6 0.1 IGHG2 ENSG00000211893 "Immunoglobulin heavy constant gamma 2 (G2m marker)" P01859 14 105639559-105644790 "FDA approved drug targets, Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "lymphoid tissue: 4319.4" "Group enriched" "Detected in some" 8 "B-cells: 2050.1;Plasma cells: 2918.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 447 "memory B-cell: 339.0;naive B-cell: 119.3" "Lineage enriched" "Detected in single" 661 "B-cells: 339.0" "Group enriched" "Detected in some" 4 "RH-30: 9.6;RPMI-8226: 25.1" HPA001245 Approved "Immunoglobulin genes" NA NA 250000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA001245: AB_1079121" "prognostic favorable (3.53e-4)" "unprognostic (6.88e-3)" "unprognostic (2.40e-2)" "unprognostic (1.55e-2)" "unprognostic (2.40e-2)" "prognostic favorable (3.30e-6)" "unprognostic (1.06e-1)" "unprognostic (6.67e-2)" "unprognostic (1.74e-1)" "unprognostic (7.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.30e-8)" "unprognostic (4.72e-2)" "unprognostic (3.32e-2)" "unprognostic (1.05e-1)" "unprognostic (7.40e-2)" 109.5 11.0 1.3 170.0 1.4 34.8 56.0 0.2 4.1 59.9 0.8 202.8 7.5 55.8 0.8 90.2 51.5 20.7 15.2 0.2 1.1 157.5 98.2 171.0 65.4 0.9 0.2 16.3 8.0 0.1 8.2 0.0 0.5 64.2 9.4 0.0 201.2 1.2 3.5 13.3 330.7 1.0 1.5 4319.4 87.2 2.3 0.3 16.7 134.4 0.0 226.0 100.4 104.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 25.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 339.0 0.5 0.0 0.3 119.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 34.5 1.3 1.4 0.2 4.1 0.2 1.1 0.9 0.2 0.5 1.5 0.3 1.8 0.2 54.5 305.3 0.0 2050.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 2.8 13.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.2 4.1 0.0 32.5 0.0 0.0 0.0 3.1 0.0 0.0 126.1 0.0 8.2 5.1 0.1 0.0 0.0 0.9 0.0 12.4 0.0 0.2 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 2918.6 0.7 0.0 3.5 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.1 305.5 0.0 0.7 0.0 IGHG3 ENSG00000211897 "Immunoglobulin heavy constant gamma 3 (G3m marker)" 14 105764503-105771405 "Immunoglobulin genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 1289.1" "Group enriched" "Detected in many" 7 "B-cells: 2548.4;Plasma cells: 4543.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 415 "memory B-cell: 211.0;naive B-cell: 64.4" "Lineage enriched" "Detected in single" 636 "B-cells: 211.0" "Group enriched" "Detected in some" 5 "HDLM-2: 23.8;Karpas-707: 18.7;U-698: 49.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.49e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.00e-5)" "unprognostic (1.92e-2)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.99e-2)" "unprognostic (8.36e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (8.46e-11)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (9.80e-2)" "unprognostic (6.79e-2)" 63.6 17.6 0.1 90.8 0.3 65.4 23.8 0.1 1.5 37.9 1.0 30.0 11.6 22.8 0.3 32.2 104.4 8.4 6.7 0.1 0.6 72.8 42.4 194.9 346.3 2.8 0.1 13.4 6.3 0.1 6.8 0.1 0.4 41.4 8.8 0.0 69.9 12.7 1.9 2.3 100.9 1.6 1.2 1289.1 65.4 31.7 0.1 27.1 87.6 0.0 929.0 87.3 29.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.3 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 6.0 3.9 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 49.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 211.0 0.0 0.0 0.0 64.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 20.7 0.1 0.3 0.1 1.5 0.1 0.6 2.8 0.1 0.4 1.2 0.1 1.0 1.9 57.7 363.7 0.0 2548.4 0.0 9.7 0.0 0.0 0.0 0.5 0.1 1.9 18.6 11.2 0.0 0.0 0.0 2.0 7.0 0.0 0.0 6.5 0.1 0.2 5.3 13.2 24.5 0.0 0.0 0.0 9.1 2.6 0.0 195.5 0.0 22.9 64.2 0.1 0.0 0.0 7.4 0.0 62.8 0.0 16.4 0.0 7.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.0 4543.8 13.3 0.0 0.5 2.2 0.0 0.0 0.0 0.7 4.7 0.7 0.0 0.0 0.0 467.3 0.0 13.5 0.1 IGHJ1 ENSG00000211905 "Immunoglobulin heavy joining 1" A0A0C4DH62 14 105865407-105865458 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 354.8;lymphoid tissue: 414.0;salivary gland: 120.1;stomach 1: 305.5" "Cell type enriched" "Detected in single" 18 "Plasma cells: 1.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 1.9" "Group enriched" "Detected in some" 72 "memory B-cell: 276.3;naive B-cell: 180.8;plasmacytoid DC: 99.0" "Group enriched" "Detected in many" 73 "B-cells: 276.3;dendritic cells: 99.0" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.7;U-698: 1.8" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.28e-3)" "unprognostic (2.05e-2)" "unprognostic (6.81e-2)" "unprognostic (9.53e-2)" "prognostic favorable (3.55e-4)" "unprognostic (2.51e-1)" "unprognostic (2.45e-1)" "unprognostic (3.00e-2)" "unprognostic (2.90e-2)" 8.6 5.3 0.1 196.9 0.1 35.6 72.8 0.0 1.9 18.6 0.2 260.2 354.8 3.3 0.0 15.7 5.2 12.6 1.4 0.1 0.1 2.3 6.1 28.5 46.8 1.3 0.0 8.2 3.1 0.4 0.0 0.7 0.5 4.3 182.6 0.0 120.1 0.5 0.0 0.0 171.1 12.0 0.3 100.2 305.5 1.0 0.2 14.6 2.9 0.0 414.0 61.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.2 276.3 0.6 2.5 0.2 180.8 0.3 0.3 0.0 0.1 0.1 99.0 0.2 29.1 0.1 0.1 0.0 1.9 0.1 0.1 1.3 0.0 0.5 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ2 ENSG00000211904 "Immunoglobulin heavy joining 2" 14 105865199-105865250 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "cervix: 48.7;intestine: 127.5;lymphoid tissue: 174.5" "Cell type enriched" "Detected in single" 6 "Plasma cells: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "medulla oblongata: 3.8" "Group enriched" "Detected in some" 18 "MAIT T-cell: 49.0;naive B-cell: 12.6" "Group enriched" "Detected in many" 45 "B-cells: 12.6;T-cells: 49.0" "Group enriched" "Detected in some" 25 "Daudi: 3.8;K-562: 1.1" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (1.27e-2)" "prognostic favorable (1.05e-4)" "unprognostic (7.40e-2)" "unprognostic (6.38e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.33e-6)" "unprognostic (4.31e-2)" "unprognostic (1.68e-1)" "unprognostic (5.48e-2)" "unprognostic (4.60e-1)" 2.0 0.0 0.2 0.0 0.5 13.3 20.5 0.2 2.0 48.7 0.1 87.2 0.0 5.4 17.9 18.0 2.1 0.8 0.1 0.2 0.4 1.2 12.0 0.0 7.6 3.8 0.8 7.7 18.9 0.6 0.0 0.0 0.5 15.0 127.5 0.0 0.0 7.1 0.0 0.0 0.0 5.8 0.6 18.8 18.2 0.1 0.5 19.6 5.1 0.0 174.5 6.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 49.0 1.3 0.4 1.6 0.4 12.6 0.0 0.2 0.2 0.0 0.6 0.0 0.0 17.1 0.2 0.5 0.2 2.0 0.2 0.4 3.8 0.8 0.5 0.6 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ3 ENSG00000242887 "Immunoglobulin heavy joining 3" 14 105864587-105864635 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 36.4;intestine: 57.9;pancreas: 61.6" "Cell type enriched" "Detected in single" 48 "Plasma cells: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 9.0;naive B-cell: 29.1" "Group enriched" "Detected in many" 7 "B-cells: 29.1;granulocytes: 9.0" "Cell line enhanced" "Detected in some" "Daudi: 1.5;RPMI-8226: 6.1;TIME: 8.0;U-251 MG: 2.6" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.67e-4)" "unprognostic (8.67e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.86e-5)" "unprognostic (3.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.82e-1)" "unprognostic (4.22e-2)" "unprognostic (2.03e-1)" "unprognostic (5.70e-2)" "prognostic unfavorable (3.24e-4)" "unprognostic (8.47e-2)" "unprognostic (2.54e-1)" "unprognostic (9.62e-2)" "unprognostic (1.30e-1)" 16.2 3.0 0.6 0.0 0.9 0.0 0.0 0.2 2.5 1.9 0.5 0.0 0.0 0.0 0.0 36.4 0.7 9.1 0.0 0.6 0.9 0.9 10.2 17.3 0.0 1.5 0.4 11.3 61.6 0.0 0.0 0.0 1.7 7.5 57.9 0.1 0.0 4.3 0.0 2.4 0.0 0.0 1.4 0.0 0.0 0.3 0.7 0.0 2.4 0.0 0.0 5.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.4 0.2 0.0 0.9 0.0 0.7 1.1 2.6 29.1 1.5 1.2 0.0 0.4 0.7 0.0 1.2 0.0 0.6 0.9 0.2 2.5 0.6 0.9 1.5 0.4 1.7 1.4 0.7 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGHJ4 ENSG00000240041 "Immunoglobulin heavy joining 4" 14 105864215-105864260 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 416.7;lymphoid tissue: 1568.0;urinary bladder: 551.2" "Cell type enriched" "Detected in single" 148 "Plasma cells: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 187 "memory B-cell: 6029.7;naive B-cell: 2618.0" "Lineage enriched" "Detected in all" 261 "B-cells: 6029.7" "Cell line enriched" "Detected in some" 87 "U-698: 3990.3" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 7.2 0.0 2.9 0.0 240.0 0.9 10.8 0.0 3.6 377.5 0.0 0.0 0.0 200.2 7.4 4.1 12.3 0.9 2.5 0.0 39.1 0.0 0.0 8.9 30.7 0.0 0.0 13.6 0.0 2.5 22.3 7.0 416.7 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.0 45.4 7.3 3.7 3.1 32.3 3.9 0.0 1568.0 551.2 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 14.0 17.5 0.0 0.0 0.0 0.0 6.8 3.6 0.0 0.0 0.0 0.0 0.0 8.9 0.0 45.8 0.0 0.0 6.2 0.0 3990.3 0.0 12.2 0.0 13.9 3.6 5.4 5.0 1.3 3.0 6029.7 13.2 4.0 23.1 2618.0 1.5 6.0 20.1 3.3 6.0 0.0 6.6 1048.2 7.2 2.9 0.9 10.8 0.9 2.5 8.9 30.7 22.3 2.0 3.1 1.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ5 ENSG00000242472 "Immunoglobulin heavy joining 5" 14 105863814-105863862 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 33.5;breast: 73.2;intestine: 72.3;prostate: 32.7" "Cell type enriched" "Detected in single" 397 "Plasma cells: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 263 "memory B-cell: 1081.0" "Lineage enriched" "Detected in many" 263 "B-cells: 1081.0" "Group enriched" "Detected in some" 11 "HL-60: 10.5;REH: 14.0;RH-30: 18.0" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" 33.5 0.0 0.7 0.0 3.7 0.0 73.2 0.7 2.0 0.0 2.0 72.3 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.9 4.2 4.5 29.4 17.1 0.0 3.1 1.0 0.0 4.7 0.0 0.0 0.0 1.9 32.7 0.2 0.2 0.0 0.0 0.0 7.9 0.0 0.0 1.6 0.0 0.0 0.4 1.3 0.0 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.6 2.1 1.2 0.7 1081.0 0.4 0.6 4.1 0.0 2.6 0.9 2.3 0.7 0.6 0.0 1.1 316.0 0.7 3.7 0.7 2.0 0.9 4.2 3.1 1.0 1.9 1.6 1.3 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHJ6 ENSG00000211900 "Immunoglobulin heavy joining 6" 14 105863198-105863258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "cervix: 142.4;intestine: 38.6;lung: 47.0;testis: 151.4;urinary bladder: 113.5" "Cell type enriched" "Detected in single" 56 "Plasma cells: 39.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 14 "memory B-cell: 316.2;naive B-cell: 112.7" "Lineage enriched" "Detected in many" 21 "B-cells: 316.2" "Cell line enhanced" "Detected in some" "U-266/84: 1.3;U-937: 1.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.1 0.9 142.4 0.0 2.6 38.6 1.0 0.0 0.0 2.1 0.5 0.9 0.3 0.0 3.0 2.4 47.0 0.4 0.4 0.1 0.0 0.0 3.7 0.0 0.0 0.3 3.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 151.4 0.3 0.0 0.7 0.0 10.7 113.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.2 0.0 3.5 3.5 0.8 0.3 0.0 0.2 316.2 0.5 0.6 0.5 112.7 0.6 0.3 14.8 0.2 1.0 0.0 0.1 89.2 0.0 0.0 0.1 0.9 0.3 0.0 0.4 0.1 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV1-18 ENSG00000211945 "Immunoglobulin heavy variable 1-18" A0A0C4DH31 14 106184901-106185394 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 486.7;salivary gland: 234.3" "Cell type enriched" "Detected in some" 259 "Plasma cells: 13773.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 21 "memory B-cell: 73.2" "Lineage enriched" "Detected in many" 21 "B-cells: 73.2" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HL-60: 3.0;RPMI-8226: 2.9;TIME: 1.6" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.47e-4)" "unprognostic (2.53e-2)" "unprognostic (8.73e-3)" "unprognostic (2.56e-2)" "unprognostic (9.67e-3)" "prognostic favorable (8.27e-4)" "unprognostic (5.47e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-1)" "unprognostic (3.50e-2)" "unprognostic (3.60e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (5.84e-7)" "unprognostic (3.22e-1)" "unprognostic (2.62e-1)" "unprognostic (2.87e-1)" "unprognostic (2.44e-2)" 22.0 3.5 0.0 0.0 0.3 0.0 22.9 0.0 0.6 54.6 0.0 223.2 0.0 8.9 4.5 162.5 24.3 7.7 2.3 0.0 0.0 16.2 14.3 58.3 0.0 0.6 0.1 8.5 3.2 1.9 1.3 0.2 0.4 10.8 0.0 0.0 234.3 0.0 0.4 1.3 103.2 2.6 0.0 486.7 84.0 0.5 0.1 0.0 33.9 0.2 0.0 156.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.9 0.0 0.0 0.0 0.6 0.5 0.8 0.0 0.0 1.1 1.2 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 1.0 0.5 0.0 0.3 0.0 1.4 0.0 3.4 0.0 0.1 0.0 0.0 0.1 73.2 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.6 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 50.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.5 53.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 13773.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 3.2 0.0 0.1 0.0 IGHV1-2 V35 ENSG00000211934 "Immunoglobulin heavy variable 1-2" P23083 14 105986582-105987083 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 462.7;lymphoid tissue: 1157.3" "Cell type enriched" "Detected in some" 38 "Plasma cells: 609.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 52 "memory B-cell: 285.2;naive B-cell: 347.4" "Lineage enriched" "Detected in many" 57 "B-cells: 347.4" "Cell line enriched" "Detected in some" 8 "U-266/70: 14302.7" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.63e-3)" "unprognostic (1.09e-3)" "unprognostic (1.88e-1)" "unprognostic (9.46e-2)" "unprognostic (5.78e-2)" "prognostic favorable (1.67e-5)" "unprognostic (9.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "unprognostic (2.37e-1)" "unprognostic (1.99e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (2.17e-2)" "unprognostic (8.59e-2)" "unprognostic (3.19e-1)" "unprognostic (1.17e-2)" 16.7 43.1 0.3 364.1 0.2 76.0 84.1 0.0 1.2 41.5 0.5 462.7 223.7 13.1 1.3 34.5 58.5 54.4 26.2 0.0 0.1 13.7 18.9 60.7 404.9 0.4 0.0 36.5 3.0 0.6 1.3 0.6 0.2 23.2 283.8 0.0 222.4 52.5 0.4 4.5 121.9 7.5 0.2 393.2 216.1 35.0 0.1 72.1 33.7 0.0 1157.3 255.5 8.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 4.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 2.6 0.0 0.0 2.3 0.4 2.8 0.0 0.0 3.1 0.6 0.5 0.0 0.0 1.3 1.8 0.1 0.0 0.6 0.0 0.0 0.2 0.3 0.0 1.5 0.0 1.3 14302.7 1755.5 0.5 0.0 0.4 0.0 0.3 0.6 0.1 0.3 0.0 0.2 285.2 1.6 0.7 0.2 347.4 1.5 0.6 6.1 0.2 0.3 0.5 1.1 34.0 0.3 0.2 0.0 1.2 0.0 0.1 0.4 0.0 0.2 0.2 0.1 0.6 0.0 0.0 1.3 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 609.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 IGHV1-24 ENSG00000211950 "Immunoglobulin heavy variable 1-24" A0A0C4DH33 14 106276548-106277043 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 186.8;salivary gland: 76.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 231.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "medulla oblongata: 1.2" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.8" "Lineage enriched" "Detected in single" 9 "B-cells: 2.8" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HL-60: 1.8;JURKAT: 1.3;RH-30: 1.4" "Immunoglobulin genes" NA NA 3100000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.01e-4)" "unprognostic (2.67e-2)" "unprognostic (1.66e-2)" "unprognostic (1.93e-3)" "prognostic favorable (3.61e-4)" "unprognostic (1.28e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.59e-1)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.07e-7)" "unprognostic (5.43e-2)" "unprognostic (3.14e-2)" "unprognostic (3.17e-1)" "unprognostic (4.78e-2)" 6.8 1.4 0.1 33.7 0.0 0.0 8.5 0.0 0.3 56.3 0.1 30.5 0.0 5.7 0.0 46.2 6.5 4.6 1.8 0.0 0.1 7.0 6.4 17.7 0.0 1.2 0.1 19.6 1.4 0.1 0.4 0.3 0.0 3.1 14.0 0.0 76.3 0.0 0.1 0.8 24.0 2.1 0.0 186.8 37.0 14.2 0.0 0.4 14.5 0.0 18.4 63.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.8 0.1 0.0 0.0 2.8 0.1 0.2 0.0 0.0 0.0 0.0 0.1 3.6 0.1 0.0 0.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.9 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 19.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 231.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 5.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-3 VI-3B ENSG00000211935 "Immunoglobulin heavy variable 1-3" A0A0C4DH29 14 106005095-106005574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 223.2;lymphoid tissue: 629.4" "Cell type enriched" "Detected in some" 335 "Plasma cells: 13473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "memory B-cell: 52.8;naive B-cell: 27.8" "Lineage enriched" "Detected in many" 9 "B-cells: 52.8" "Cell line enriched" "Detected in some" 11 "Karpas-707: 148.5" "Immunoglobulin genes" NA NA 2600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.39e-2)" "unprognostic (3.81e-3)" "unprognostic (2.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.41e-3)" "unprognostic (2.42e-1)" "unprognostic (7.85e-2)" "unprognostic (5.60e-2)" "unprognostic (3.07e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (5.67e-7)" "unprognostic (7.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-1)" "unprognostic (3.26e-1)" 10.6 59.3 0.0 207.8 0.0 36.4 46.7 0.0 0.5 41.6 0.3 193.3 218.5 4.8 15.3 45.5 6.5 85.4 3.2 0.0 0.1 8.2 8.9 40.9 171.8 0.2 0.0 8.4 7.0 0.3 0.6 0.1 0.1 6.0 223.2 0.0 120.6 23.5 0.6 0.9 140.9 11.2 0.0 246.6 189.1 0.4 0.1 57.8 24.2 0.0 629.4 92.1 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 14.1 1.0 148.5 0.0 0.0 0.8 1.1 0.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 10.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.7 0.0 2.8 1.4 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 52.8 0.6 0.2 0.0 27.8 1.6 0.5 0.0 0.0 0.0 5.8 1.7 6.1 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 40.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 27.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13473.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 4.5 0.0 0.0 0.0 IGHV1-46 ENSG00000211962 "Immunoglobulin heavy variable 1-46" P01743 14 106511117-106511856 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 67.9;lymphoid tissue: 125.7;salivary gland: 67.4" "Cell type enriched" "Detected in some" 201 "Plasma cells: 8432.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;RPMI-8226: 1.2;SH-SY5Y: 1.2;TIME: 2.3;U-266/70: 1.1;U-266/84: 1.2" "Immunoglobulin genes" NA NA 2900000000 "Cluster 24: B-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.28e-4)" "unprognostic (2.49e-2)" "prognostic favorable (7.34e-4)" "unprognostic (1.10e-2)" "unprognostic (3.53e-2)" "unprognostic (1.80e-3)" "unprognostic (1.87e-1)" "unprognostic (6.76e-2)" "unprognostic (8.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-1)" "prognostic unfavorable (1.56e-6)" "unprognostic (6.19e-2)" "unprognostic (2.52e-1)" "unprognostic (2.27e-1)" "unprognostic (5.13e-1)" 5.1 1.3 0.0 0.0 0.0 0.0 7.2 0.0 0.1 6.2 0.0 67.9 0.0 2.5 1.0 4.9 3.5 0.7 5.0 0.0 0.0 3.2 4.2 15.3 0.0 0.1 0.0 3.0 5.3 0.1 0.3 0.3 0.1 1.9 45.1 0.0 67.4 0.0 0.1 0.7 34.2 0.0 0.0 125.7 25.1 0.2 0.0 0.0 10.5 0.2 0.0 5.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 0.5 1.2 0.2 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.3 0.0 0.1 1.1 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 1.9 41.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8432.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 IGHV1-69 IGHV1-E ENSG00000211973 "Immunoglobulin heavy variable 1-69" P01742 14 106714684-106715181 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 139.1;lymphoid tissue: 170.2;urinary bladder: 162.6" "Cell type enriched" "Detected in some" 85 "Plasma cells: 231.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 2.5;pons: 3.0" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0;MOLT-4: 6.2;SCLC-21H: 1.1;U-698: 1.9" "Immunoglobulin genes" NA NA 2700000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.51e-3)" "unprognostic (7.03e-2)" "prognostic favorable (9.56e-5)" "prognostic favorable (8.32e-4)" "unprognostic (1.06e-2)" "unprognostic (1.69e-1)" "unprognostic (1.82e-1)" "unprognostic (3.64e-1)" "unprognostic (1.64e-2)" "unprognostic (1.70e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (1.28e-1)" "unprognostic (2.95e-1)" "unprognostic (8.20e-2)" "unprognostic (6.82e-2)" 7.7 1.4 0.0 0.0 0.1 0.1 6.5 0.0 0.0 21.4 0.1 56.9 0.0 6.9 0.0 7.0 5.7 77.4 0.7 0.0 0.1 7.0 4.8 18.0 0.0 2.5 0.0 2.0 0.8 1.8 0.5 0.0 3.0 4.6 139.1 0.0 55.9 13.0 0.1 0.5 31.7 6.8 0.0 170.2 31.0 0.1 0.0 0.0 25.2 0.0 0.0 162.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.9 0.0 0.0 1.3 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 IGHV1-69D ENSG00000280411 "Immunoglobulin heavy variable 1-69D" A0A0B4J2H0 14 106762092-106762588 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2878.6;stomach 1: 989.1" "Group enriched" "Detected in some" 6 "Plasma cells: 5.8;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 225 "memory B-cell: 184.5;naive B-cell: 433.4" "Lineage enriched" "Detected in many" 316 "B-cells: 433.4" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HL-60: 2.3;MOLT-4: 4.2;RPMI-8226: 2.5;U-266/70: 3.3;U-698: 7.9" "Immunoglobulin genes" NA NA 1200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (3.32e-3)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (3.77e-2)" "unprognostic (2.49e-4)" "prognostic favorable (2.88e-4)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (1.62e-1)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.72e-8)" "unprognostic (5.14e-2)" "unprognostic (9.96e-2)" "unprognostic (2.84e-2)" "unprognostic (2.08e-2)" 26.1 95.3 0.1 462.7 0.1 113.1 146.7 0.0 0.7 37.5 1.0 628.2 491.2 15.0 16.8 98.6 16.0 78.0 20.2 0.0 0.1 17.5 46.6 149.6 2878.6 1.1 0.0 35.9 3.3 0.6 1.1 0.4 0.1 16.5 406.2 0.0 385.0 100.0 0.5 5.2 121.3 43.8 0.2 452.7 989.1 6.8 0.0 135.7 38.3 0.0 2219.2 295.4 11.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.2 0.3 1.3 0.0 0.0 0.9 0.8 2.5 0.0 0.0 0.8 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.6 0.4 3.3 0.1 7.9 0.0 0.7 0.0 0.8 0.3 0.1 0.0 0.0 0.2 184.5 0.3 0.0 0.2 433.4 0.4 0.1 0.4 0.2 0.4 1.3 0.2 33.5 0.1 0.1 0.0 0.7 0.0 0.1 1.1 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGHV2-5 ENSG00000211937 "Immunoglobulin heavy variable 2-5" P01817 14 106037902-106038365 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 465.8;lymphoid tissue: 1426.6;stomach 1: 707.9" "Cell type enriched" "Detected in some" 333 "Plasma cells: 9414.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "memory B-cell: 66.7;naive B-cell: 67.3" "Lineage enriched" "Detected in many" 22 "B-cells: 67.3" "Cell line enriched" "Detected in some" 5 "Karpas-707: 8.8" "Immunoglobulin genes" NA NA 700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.38e-2)" "unprognostic (4.10e-3)" "unprognostic (2.51e-2)" "unprognostic (6.62e-3)" "prognostic favorable (1.41e-4)" "unprognostic (1.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.63e-1)" "unprognostic (1.47e-1)" "unprognostic (8.45e-2)" "unprognostic (3.38e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" 16.9 5.0 0.0 183.0 0.2 112.8 106.0 0.0 0.5 45.0 0.2 465.8 266.6 7.5 2.5 27.9 10.7 65.0 5.8 0.0 0.1 20.9 16.4 83.9 188.0 0.5 0.2 13.8 9.3 1.0 1.1 0.3 0.7 9.4 296.3 0.0 201.4 8.8 0.4 2.9 177.0 17.4 0.3 351.0 707.9 2.3 0.0 121.5 27.6 0.0 1426.6 249.3 12.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.6 0.4 0.0 0.1 1.2 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.4 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 66.7 0.0 0.0 0.1 67.3 0.1 0.1 3.0 0.0 0.0 0.0 0.0 10.5 0.0 0.2 0.0 0.5 0.0 0.1 0.5 0.2 0.7 0.3 0.0 0.4 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.1 27.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 3.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9414.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 IGHV2-70 ENSG00000274576 "Immunoglobulin heavy variable 2-70" P01814 14 106770577-106771020 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "lymphoid tissue: 727.6;stomach 1: 502.1" "Cell type enriched" "Detected in single" 5 "Plasma cells: 2.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Group enriched" "Detected in some" 241 "memory B-cell: 24.6;naive B-cell: 23.5" "Lineage enriched" "Detected in single" 247 "B-cells: 24.6" "Cell line enriched" "Detected in some" 8 "U-698: 12.4" "Immunoglobulin genes" NA NA 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (8.01e-3)" "unprognostic (2.93e-2)" "unprognostic (3.56e-3)" "unprognostic (2.38e-2)" "unprognostic (1.12e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (3.14e-1)" "unprognostic (8.29e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (9.10e-2)" "unprognostic (2.50e-1)" "unprognostic (8.93e-2)" "unprognostic (2.91e-1)" 7.3 25.7 0.0 96.2 0.0 69.2 86.1 0.0 5.2 62.3 0.0 86.7 53.2 4.1 0.0 44.3 8.1 37.5 2.5 0.0 1.4 4.8 13.2 69.9 82.7 0.1 1.1 5.0 1.0 0.9 0.3 0.2 0.1 6.8 82.8 0.0 94.5 14.1 0.1 0.9 42.1 2.5 2.2 156.4 502.1 1.2 0.0 59.5 8.5 0.0 727.6 50.4 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.4 0.8 0.0 0.0 0.8 0.6 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.7 0.0 0.1 0.0 12.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 5.2 0.0 1.4 0.1 1.1 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-11 ENSG00000211941 "Immunoglobulin heavy variable 3-11" P01762 14 106116635-106117204 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 220.1;lymphoid tissue: 613.1;stomach 1: 206.7" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1655.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 445 "memory B-cell: 43.1;naive B-cell: 45.7" "Lineage enriched" "Detected in single" 458 "B-cells: 45.7" "Cell line enhanced" "Detected in some" "Daudi: 1.1;SH-SY5Y: 1.2" "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.07e-3)" "unprognostic (4.84e-2)" "unprognostic (5.81e-3)" "unprognostic (1.07e-2)" "unprognostic (1.04e-2)" "prognostic favorable (3.42e-5)" "unprognostic (4.12e-1)" "unprognostic (6.50e-2)" "unprognostic (2.37e-1)" "unprognostic (3.44e-2)" "unprognostic (3.51e-1)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.86e-1)" "unprognostic (1.30e-1)" 9.3 25.9 0.0 175.0 0.0 38.0 66.0 0.0 0.5 34.7 0.2 220.1 193.4 6.8 12.3 38.6 6.6 43.7 8.6 0.0 0.0 6.8 10.5 29.1 123.7 0.8 0.0 7.8 2.0 0.2 0.8 0.0 0.1 4.0 167.9 0.0 119.7 3.7 0.3 0.7 116.8 11.2 0.1 219.2 206.7 1.3 0.4 44.9 17.0 0.0 613.1 109.4 8.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.5 0.0 0.0 0.8 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1655.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGHV3-15 ENSG00000211943 "Immunoglobulin heavy variable 3-15" A0A0B4J1V0 14 106153624-106154163 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 183.3;lymphoid tissue: 380.2;salivary gland: 177.7;stomach 1: 112.8;urinary bladder: 172.6" "Cell type enriched" "Detected in some" 112 "Plasma cells: 6281.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9 "MAIT T-cell: 21.6;memory B-cell: 24.4" "Group enriched" "Detected in many" 9 "B-cells: 24.4;T-cells: 21.6" "Cell line enhanced" "Detected in some" "BEWO: 2.2;Daudi: 1.9;HL-60: 2.1;K-562: 2.0;NB-4: 2.4;RH-30: 1.9;RPMI-8226: 4.1;SH-SY5Y: 3.7" "Immunoglobulin genes" NA NA 20000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (8.85e-5)" "unprognostic (2.07e-1)" "unprognostic (1.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "prognostic favorable (3.34e-5)" "unprognostic (5.20e-2)" "unprognostic (2.44e-1)" "unprognostic (9.67e-2)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (2.19e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (6.85e-2)" "unprognostic (6.92e-2)" "unprognostic (7.12e-2)" "unprognostic (3.63e-1)" 12.2 36.8 0.0 24.7 0.5 1.8 23.2 0.0 1.2 13.0 0.1 183.3 4.5 5.0 0.9 11.7 16.3 29.6 1.4 0.0 0.2 9.1 10.6 40.0 0.0 1.0 0.0 5.8 19.1 0.4 1.3 0.4 0.3 9.5 14.6 0.0 177.7 23.0 0.8 4.2 107.2 0.3 0.0 380.2 112.8 0.5 0.0 0.0 14.9 0.0 10.4 172.6 9.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.8 2.4 0.7 0.0 0.0 0.0 1.9 4.1 0.0 0.0 0.0 3.7 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 1.6 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.1 0.1 0.0 21.6 24.4 0.1 0.2 0.2 0.0 0.2 0.1 2.5 0.0 0.0 0.2 0.1 1.8 0.0 0.5 0.0 1.2 0.0 0.2 1.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.1 1.1 0.6 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6281.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.3 0.0 IGHV3-20 ENSG00000211946 "Immunoglobulin heavy variable 3-20" A0A0C4DH32 14 106210936-106211453 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 99.2;lymphoid tissue: 216.6;stomach 1: 122.5;urinary bladder: 81.9" "Cell type enriched" "Detected in some" 24 "Plasma cells: 142.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 242 "memory B-cell: 28.5;naive B-cell: 19.8" "Lineage enriched" "Detected in single" 286 "B-cells: 28.5" "Cell line enhanced" "Detected in single" "Daudi: 1.2" "Immunoglobulin genes" NA NA 2200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.56e-5)" "unprognostic (2.30e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-2)" "prognostic favorable (2.93e-4)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.42e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (2.10e-4)" "unprognostic (2.09e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.76e-1)" 2.8 2.1 0.0 36.3 0.2 22.6 23.7 0.0 0.1 17.4 0.2 64.8 99.2 1.8 0.0 10.1 2.2 20.7 3.1 0.0 0.0 1.5 4.7 10.5 58.0 0.1 0.0 2.7 0.4 0.1 0.2 0.0 0.0 1.2 62.5 0.0 43.1 1.4 0.0 0.3 37.7 2.0 0.0 59.6 122.5 1.1 0.0 16.6 2.8 0.0 216.6 81.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.5 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 142.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 IGHV3-21 ENSG00000211947 "Immunoglobulin heavy variable 3-21" A0A0B4J1V1 14 106235064-106235594 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 209.7;lymphoid tissue: 398.1;salivary gland: 213.2" "Cell type enriched" "Detected in some" 86 "Plasma cells: 3885.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.1;NB-4: 2.1;NTERA-2: 1.2;RH-30: 2.3;TIME: 1.9" "Immunoglobulin genes" NA NA 37000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.30e-4)" "unprognostic (1.21e-2)" "unprognostic (7.19e-3)" "unprognostic (1.51e-2)" "unprognostic (9.16e-3)" "prognostic favorable (9.34e-4)" "unprognostic (3.15e-2)" "unprognostic (1.76e-1)" "unprognostic (4.42e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (4.05e-1)" "prognostic unfavorable (9.31e-8)" "unprognostic (1.73e-1)" "unprognostic (3.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.77e-1)" 18.1 2.7 0.3 0.0 0.3 0.0 24.8 0.2 1.1 16.8 0.3 209.7 0.0 7.1 0.9 17.4 30.9 0.0 2.0 0.2 0.3 15.4 10.7 55.3 0.0 0.4 0.3 2.9 16.2 2.3 1.3 0.6 0.4 7.2 0.0 0.0 213.2 0.3 0.4 4.3 111.3 0.8 0.4 398.1 83.0 0.4 0.3 0.0 25.6 0.0 0.0 27.7 10.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 2.1 1.2 0.0 0.0 0.7 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.2 1.1 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.0 44.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 1.0 21.4 0.0 0.0 0.1 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3885.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGHV3-23 ENSG00000211949 "Immunoglobulin heavy variable 3-23" P01764 14 106268606-106269140 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1683.1;lymphoid tissue: 2989.8" "Cell type enriched" "Detected in some" 139 "Plasma cells: 15979.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 406 "memory B-cell: 548.5;naive B-cell: 336.7" "Lineage enriched" "Detected in many" 503 "B-cells: 548.5" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HL-60: 3.3;NB-4: 4.1;RH-30: 3.0;RPMI-8226: 9.0;SH-SY5Y: 5.8" "Immunoglobulin genes" NA NA 42000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (5.43e-2)" "unprognostic (9.68e-3)" "unprognostic (3.31e-3)" "unprognostic (1.34e-2)" "prognostic favorable (3.85e-4)" "unprognostic (3.26e-1)" "unprognostic (4.79e-1)" "unprognostic (7.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.79e-7)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.36e-1)" "unprognostic (6.42e-2)" 66.5 189.3 0.4 912.2 0.4 185.5 343.1 0.1 2.1 80.1 1.5 1683.1 1640.8 37.0 9.8 342.6 30.1 231.2 46.4 0.1 0.3 27.3 56.4 248.7 859.5 0.8 0.1 42.6 31.0 1.5 2.7 0.9 0.4 35.3 1087.1 0.1 697.8 53.4 0.9 15.0 886.8 40.0 0.8 802.7 1058.8 35.0 0.2 197.5 52.3 0.1 2989.8 993.6 27.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.2 4.1 0.7 0.0 0.0 0.6 3.0 9.0 0.0 0.0 2.7 5.8 0.8 0.1 0.0 0.0 0.0 0.0 1.8 0.0 1.3 1.3 1.1 1.5 0.0 0.3 0.0 0.9 0.0 0.4 0.4 0.1 0.2 0.0 0.1 548.5 0.2 0.3 0.3 336.7 0.1 0.2 1.0 0.2 0.2 0.2 0.8 62.4 0.4 0.4 0.1 2.1 0.1 0.3 0.8 0.1 0.4 0.8 0.2 1.4 0.1 0.0 0.0 0.0 114.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 12.0 0.0 0.0 0.0 1.6 19.4 0.0 1.3 0.0 1.8 2.0 0.2 0.0 0.0 0.1 0.0 4.1 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15979.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.1 0.0 IGHV3-30 ENSG00000270550 "Immunoglobulin heavy variable 3-30" "P01768, P0DP03" 14 106335082-106335613 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 534.0;lymphoid tissue: 1294.8;salivary gland: 459.9;stomach 1: 572.6;urinary bladder: 378.9" "Cell type enriched" "Detected in some" 184 "Plasma cells: 14426.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 409 "memory B-cell: 164.0;naive B-cell: 136.6" "Lineage enriched" "Detected in single" 446 "B-cells: 164.0" "Cell line enhanced" "Detected in some" "BEWO: 2.1;Daudi: 1.7;NB-4: 2.3;RPMI-8226: 1.7;SCLC-21H: 1.7;SH-SY5Y: 3.0;U-266/70: 1.3" "Immunoglobulin genes" NA NA 8500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.12e-3)" "unprognostic (5.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-3)" "unprognostic (1.72e-2)" "prognostic favorable (3.23e-5)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.94e-2)" "unprognostic (2.94e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.32e-1)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (6.96e-2)" 25.3 38.5 0.1 320.5 0.2 119.7 143.9 0.0 0.4 49.3 0.5 534.0 265.5 13.3 0.0 134.6 44.8 146.5 30.3 0.4 0.2 29.2 25.1 128.2 374.9 0.6 0.2 23.0 12.3 0.7 3.3 0.7 0.2 18.6 254.9 0.0 459.9 20.4 0.9 3.5 296.1 23.6 0.1 797.4 572.6 5.9 0.1 158.2 76.6 0.1 1294.8 378.9 34.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 1.0 1.7 0.0 0.0 1.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 164.0 0.2 0.0 0.1 136.6 0.3 0.1 0.3 0.0 0.0 0.2 0.0 24.4 0.1 0.2 0.0 0.4 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 78.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 5.4 16.3 0.0 1.3 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14426.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 IGHV3-33 ENSG00000211955 "Immunoglobulin heavy variable 3-33" P01772 14 106359793-106360324 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1066.7;lymphoid tissue: 2371.2;stomach 1: 1778.8" "Cell type enriched" "Detected in some" 26 "Plasma cells: 556.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "Group enriched" "Detected in many" 101 "memory B-cell: 378.9;naive B-cell: 364.1" "Lineage enriched" "Detected in many" 103 "B-cells: 378.9" "Cell line enhanced" "Detected in some" "HDLM-2: 5.4;HL-60: 5.3;RPMI-8226: 7.7;SH-SY5Y: 3.8;U-266/70: 8.1" "Immunoglobulin genes" NA NA 7500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.04e-3)" "unprognostic (2.38e-2)" "unprognostic (8.95e-3)" "prognostic favorable (6.36e-4)" "unprognostic (6.84e-2)" "prognostic favorable (7.19e-5)" "unprognostic (1.80e-1)" "unprognostic (1.95e-1)" "unprognostic (7.31e-2)" "unprognostic (3.82e-2)" "unprognostic (1.70e-1)" "unprognostic (5.18e-1)" "prognostic unfavorable (4.10e-6)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (3.26e-1)" "unprognostic (5.92e-2)" 27.9 67.4 1.0 513.8 0.8 117.8 289.5 0.2 4.0 53.6 2.4 1066.7 882.1 16.2 14.5 127.5 18.9 141.9 32.9 0.2 0.4 15.7 41.8 210.1 795.2 1.4 0.2 110.0 29.4 1.9 1.7 0.8 0.4 23.2 775.6 0.0 619.6 39.5 0.5 3.6 343.9 37.3 0.5 476.1 1778.8 29.4 0.7 296.8 42.2 0.1 2371.2 379.8 18.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 5.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 0.8 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.8 2.9 7.7 0.0 0.0 1.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 0.7 8.1 0.0 0.2 0.0 0.8 0.0 0.2 0.6 0.1 1.1 0.0 1.9 378.9 3.6 0.9 0.3 364.1 1.4 0.6 1.0 0.2 0.1 0.2 0.5 44.6 1.0 0.8 0.2 4.0 0.2 0.4 1.4 0.2 0.4 0.5 0.7 0.7 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 10.0 2.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 556.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGHV3-43 ENSG00000232216 "Immunoglobulin heavy variable 3-43" A0A0B4J1X8 14 106470264-106470800 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 211.9;stomach 1: 312.2;urinary bladder: 153.0" "Cell type enriched" "Detected in some" 28 "Plasma cells: 557.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 321 "memory B-cell: 29.4;naive B-cell: 39.0" "Lineage enriched" "Detected in single" 366 "B-cells: 39.0" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.8;SH-SY5Y: 2.3" "Immunoglobulin genes" NA NA 4000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.31e-4)" "unprognostic (2.22e-2)" "prognostic favorable (1.46e-4)" "unprognostic (4.87e-3)" "prognostic favorable (8.20e-4)" "unprognostic (2.36e-1)" "unprognostic (1.34e-1)" "unprognostic (4.63e-1)" "unprognostic (7.27e-3)" "unprognostic (4.50e-2)" "unprognostic (8.73e-2)" "prognostic unfavorable (2.40e-5)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.75e-2)" 9.3 2.3 0.0 23.7 0.3 11.5 43.7 0.0 0.3 46.0 0.0 101.8 102.5 2.0 0.0 10.2 3.5 10.7 0.4 0.0 0.0 2.7 9.8 10.8 4.3 0.7 0.0 4.2 2.2 1.0 0.3 0.1 0.2 2.7 66.1 0.0 58.1 5.4 0.1 1.0 48.3 4.4 0.0 83.7 312.2 0.2 0.1 0.0 3.8 0.0 211.9 153.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.5 2.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 557.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 IGHV3-48 ENSG00000211964 "Immunoglobulin heavy variable 3-48" P01763 14 106537810-106538344 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 516.4;lymphoid tissue: 858.8;stomach 1: 404.9" "Cell type enriched" "Detected in some" 100 "Plasma cells: 5878.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 527 "memory B-cell: 187.1;naive B-cell: 97.5" "Lineage enriched" "Detected in single" 693 "B-cells: 187.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.5;SH-SY5Y: 1.6" "Immunoglobulin genes" NA NA 49000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.19e-3)" "unprognostic (1.87e-2)" "unprognostic (5.12e-2)" "unprognostic (9.07e-3)" "unprognostic (1.77e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.23e-1)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-2)" "unprognostic (2.64e-1)" "unprognostic (2.44e-1)" "prognostic unfavorable (4.88e-8)" "unprognostic (1.89e-1)" "unprognostic (1.25e-1)" "unprognostic (1.35e-1)" "unprognostic (2.15e-1)" 8.7 22.9 0.0 232.6 0.0 81.2 56.4 0.0 1.3 25.9 0.2 434.1 516.4 8.1 0.1 33.4 12.1 38.6 6.9 0.0 0.0 10.8 18.6 32.3 125.3 0.3 0.0 12.2 8.8 0.9 0.9 0.1 0.7 6.8 253.2 0.0 164.6 16.0 0.6 1.6 134.4 17.7 0.1 271.1 404.9 27.9 0.0 36.3 16.0 0.0 858.8 248.6 7.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.9 0.4 0.0 0.0 0.0 0.8 0.9 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 187.1 0.0 0.0 0.1 97.5 0.0 0.1 0.1 0.0 0.0 0.0 0.2 22.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 58.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.7 17.9 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5878.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 IGHV3-49 ENSG00000211965 "Immunoglobulin heavy variable 3-49" A0A0A0MS15 14 106556936-106557477 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 210.7;lymphoid tissue: 373.5;stomach 1: 182.3" "Cell type enriched" "Detected in some" 46 "Plasma cells: 717.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 187 "memory B-cell: 59.4;naive B-cell: 42.2" "Lineage enriched" "Detected in single" 219 "B-cells: 59.4" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" "Immunoglobulin genes" NA NA 1600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (7.16e-4)" "unprognostic (7.91e-3)" "unprognostic (2.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.12e-1)" "prognostic favorable (2.34e-6)" "unprognostic (4.47e-2)" "unprognostic (4.30e-2)" "unprognostic (7.00e-3)" "unprognostic (9.17e-2)" "unprognostic (2.18e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (1.43e-6)" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (8.96e-2)" "unprognostic (3.00e-1)" 20.8 7.1 0.0 112.3 0.0 45.7 42.5 0.0 0.5 11.5 0.3 210.7 184.4 4.6 3.9 20.0 5.1 10.9 9.4 0.0 0.2 5.0 12.8 43.2 108.6 0.7 0.0 26.5 1.7 0.2 0.4 0.0 0.3 3.0 139.3 0.0 88.5 12.1 0.2 0.4 88.2 11.5 0.1 183.1 182.3 1.8 0.1 21.4 9.7 0.0 373.5 100.0 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.4 0.0 0.0 0.0 42.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 4.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 717.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 IGHV3-53 ENSG00000211967 "Immunoglobulin heavy variable 3-53" P01767 14 106592676-106593347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 81.5;lymphoid tissue: 129.5;stomach 1: 43.3" "Cell type enriched" "Detected in some" 22 "Plasma cells: 176.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 99 "memory B-cell: 54.7;naive B-cell: 52.7" "Lineage enriched" "Detected in single" 101 "B-cells: 54.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 4300000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.41e-3)" "unprognostic (1.12e-1)" "unprognostic (2.46e-3)" "prognostic favorable (5.66e-4)" "prognostic favorable (3.95e-4)" "unprognostic (3.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.82e-2)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "prognostic unfavorable (2.04e-5)" "unprognostic (1.79e-1)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.72e-1)" 2.9 0.8 0.0 37.1 0.0 7.9 15.5 0.0 0.1 4.7 0.0 66.5 81.5 1.0 0.3 4.1 1.9 6.7 1.4 0.0 0.0 1.8 2.8 7.7 38.5 0.1 0.0 3.2 1.3 0.1 0.1 0.0 0.0 1.1 74.0 0.0 32.2 1.9 0.0 0.3 33.9 2.3 0.0 66.9 43.3 1.6 0.0 8.2 4.6 0.0 129.5 10.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 54.7 0.0 0.0 0.0 52.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV3-64D ENSG00000282639 "Immunoglobulin heavy variable 3-64D" A0A0J9YX35 14 106088122-106088573 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 145.2;lymphoid tissue: 272.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 301 "memory B-cell: 43.3;naive B-cell: 18.7" "Lineage enriched" "Detected in single" 420 "B-cells: 43.3" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 7: Non-specific - Mitochondria" 8.3 0.5 0.2 140.3 0.1 10.9 84.2 0.0 0.8 12.9 0.3 130.9 20.4 3.3 1.4 35.4 7.8 46.3 4.8 0.5 0.0 1.5 4.2 36.7 48.8 0.1 0.0 5.1 8.1 0.1 0.1 0.1 0.0 4.1 145.2 0.0 28.9 11.5 0.0 3.8 68.8 3.6 0.1 67.4 74.8 0.5 0.0 16.5 2.9 0.0 272.7 40.5 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.3 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGHV3-66 ENSG00000211972 "Immunoglobulin heavy variable 3-66" A0A0C4DH42 14 106675017-106675544 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.3;intestine: 59.5;urinary bladder: 103.9" "Cell type enriched" "Detected in some" 107 "Plasma cells: 958.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 137 "memory B-cell: 39.7" "Lineage enriched" "Detected in single" 137 "B-cells: 39.7" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.7;U-2 OS: 2.3" "Immunoglobulin genes" NA NA 7200000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.43e-6)" "unprognostic (2.48e-2)" "unprognostic (5.05e-3)" "unprognostic (1.31e-3)" "unprognostic (2.20e-3)" "unprognostic (8.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.83e-2)" "unprognostic (1.87e-2)" "unprognostic (6.95e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.89e-6)" "unprognostic (3.87e-1)" "unprognostic (1.21e-1)" "unprognostic (2.84e-1)" "unprognostic (1.19e-1)" 3.8 0.9 0.0 0.0 0.1 11.1 3.9 0.0 0.4 15.3 0.3 59.5 0.0 1.4 1.2 27.0 3.2 47.3 0.3 0.0 0.0 1.3 3.5 13.1 41.1 0.2 0.0 5.6 0.4 0.0 0.1 0.0 0.0 3.9 32.3 0.0 16.1 5.7 0.0 1.5 10.1 1.3 0.0 31.8 6.3 0.6 0.0 0.0 2.5 0.0 39.7 103.9 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 39.7 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 958.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV3-7 ENSG00000211938 "Immunoglobulin heavy variable 3-7" P01780 14 106062151-106062683 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 461.3;lymphoid tissue: 971.3" "Cell type enriched" "Detected in some" 255 "Plasma cells: 20463.1" "Cancer enhanced" "Detected in many" "stomach cancer: 18.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 147 "memory B-cell: 134.0;naive B-cell: 107.0" "Lineage enriched" "Detected in single" 163 "B-cells: 134.0" "Cell line enhanced" "Detected in some" "Daudi: 7.6;HL-60: 3.1;K-562: 3.0;NB-4: 3.0;RPMI-8226: 5.8;SH-SY5Y: 4.8;TIME: 2.9" "Immunoglobulin genes" NA NA 39000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.29e-2)" "unprognostic (5.57e-3)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-6)" "unprognostic (1.00e-2)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (5.46e-2)" "unprognostic (1.37e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (5.18e-2)" "unprognostic (8.50e-2)" "unprognostic (1.63e-1)" "unprognostic (7.70e-2)" 47.8 10.1 0.7 50.1 1.0 71.1 202.7 0.3 0.8 87.4 0.6 461.3 154.1 37.7 8.2 17.8 13.4 37.0 2.2 0.2 0.4 17.6 20.3 56.4 102.5 1.6 2.8 24.7 4.8 2.9 1.8 0.3 2.3 9.2 303.5 0.0 265.5 22.9 1.3 9.6 206.0 3.6 3.9 610.4 230.4 13.2 0.4 0.0 21.1 0.1 971.3 42.9 14.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.0 0.0 0.0 3.0 0.5 0.0 0.0 0.4 2.6 5.8 0.0 0.0 2.3 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.7 0.0 1.2 1.6 0.0 0.1 0.0 0.6 0.0 0.4 0.8 0.2 0.1 0.0 0.2 134.0 0.2 0.2 0.3 107.0 0.1 0.1 0.1 0.1 0.2 0.6 0.2 12.6 0.7 1.0 0.3 0.8 0.2 0.4 1.6 2.8 2.3 3.9 0.4 1.3 0.0 0.0 0.0 0.0 80.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.5 0.0 5.3 0.0 0.0 0.0 4.4 31.1 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20463.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 7.4 0.0 0.5 0.0 IGHV3-72 ENSG00000225698 "Immunoglobulin heavy variable 3-72" A0A0B4J1Y9 14 106790691-106791233 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 75.7;lymphoid tissue: 121.6;urinary bladder: 101.3" "Cell type enriched" "Detected in some" 271 "Plasma cells: 3507.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "memory B-cell: 52.4" "Lineage enriched" "Detected in many" 50 "B-cells: 52.4" "Cell line enhanced" "Detected in some" "NB-4: 1.3;RH-30: 1.3;RPMI-8226: 1.2;TIME: 2.2;U-698: 5.8" "Immunoglobulin genes" NA NA 9600000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.10e-6)" "unprognostic (2.18e-2)" "unprognostic (1.32e-2)" "unprognostic (2.93e-2)" "prognostic favorable (8.57e-5)" "unprognostic (9.14e-3)" "unprognostic (3.98e-2)" "unprognostic (1.86e-1)" "unprognostic (9.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.27e-2)" "prognostic unfavorable (4.40e-4)" "unprognostic (9.29e-2)" "unprognostic (1.29e-1)" "unprognostic (8.81e-2)" "unprognostic (1.32e-1)" 4.8 2.6 0.1 18.4 0.1 15.5 7.0 0.0 0.6 5.2 0.1 75.7 28.4 3.0 2.9 17.4 3.4 0.3 0.3 0.0 0.0 1.9 5.3 8.6 2.7 0.5 0.0 2.3 3.4 0.1 0.2 0.1 0.1 1.9 47.6 0.0 46.6 0.9 0.1 0.3 58.2 5.4 0.1 121.6 29.4 0.0 0.0 2.6 2.2 0.5 12.1 101.3 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 1.3 0.2 0.0 0.0 0.1 1.3 1.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.2 0.1 0.0 0.3 0.0 5.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 52.4 0.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.1 0.1 0.0 0.6 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.1 7.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3507.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 IGHV3-73 ENSG00000211976 "Immunoglobulin heavy variable 3-73" A0A0B4J1V6 14 106802694-106803233 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 141.8;lymphoid tissue: 83.0;urinary bladder: 81.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Cholangiocytes: 1.5;Erythroid cells: 5.3;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 86 "memory B-cell: 69.9;naive B-cell: 42.9" "Lineage enriched" "Detected in single" 107 "B-cells: 69.9" "Cell line enhanced" "Detected in some" "Daudi: 1.4;HEL: 1.1;HL-60: 1.1;K-562: 1.7" "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 57: B-cells - Immune response" "prognostic favorable (7.89e-4)" "unprognostic (3.61e-2)" "unprognostic (1.55e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.25e-7)" "unprognostic (4.23e-2)" "unprognostic (4.32e-2)" "unprognostic (5.40e-1)" "unprognostic (1.57e-2)" "unprognostic (2.27e-2)" "unprognostic (5.37e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (4.45e-1)" "unprognostic (2.52e-1)" "unprognostic (5.25e-2)" "unprognostic (4.37e-2)" 4.4 13.3 0.0 9.4 0.0 15.8 10.5 0.0 0.5 4.7 0.3 76.9 141.8 5.1 0.0 4.0 3.9 19.1 10.4 0.0 0.0 3.0 9.8 12.3 0.0 0.1 0.0 1.5 5.9 0.0 0.5 0.1 0.2 4.3 58.0 0.0 30.6 3.9 0.4 0.2 23.6 0.4 0.1 83.0 47.5 0.4 0.0 0.0 4.1 0.0 0.2 81.7 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 69.9 0.1 0.0 0.0 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 IGHV3-74 ENSG00000224650 "Immunoglobulin heavy variable 3-74" A0A0B4J1X5 14 106810442-106811131 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.9;lymphoid tissue: 327.0;salivary gland: 102.6" "Cell type enriched" "Detected in some" 454 "Plasma cells: 19404.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 861 "Daudi: 2948.0" "Immunoglobulin genes" NA NA 27000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.47e-4)" "unprognostic (9.70e-2)" "prognostic favorable (8.33e-4)" "unprognostic (6.96e-3)" "unprognostic (1.42e-1)" "prognostic favorable (7.79e-4)" "unprognostic (1.06e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-1)" "unprognostic (3.07e-2)" "unprognostic (2.42e-1)" "unprognostic (9.85e-2)" "prognostic unfavorable (4.70e-6)" "unprognostic (1.14e-1)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" 11.3 1.2 0.1 0.0 0.2 0.0 12.6 0.0 1.5 9.3 0.0 103.9 0.0 2.1 1.9 87.3 2.6 1.3 0.7 0.0 0.3 4.7 6.6 22.2 0.0 0.6 0.0 2.5 1.9 0.6 0.8 0.1 0.2 6.5 0.0 0.0 102.6 0.0 0.5 3.2 74.1 0.0 0.3 327.0 27.5 0.2 0.1 0.0 7.7 0.0 0.0 46.4 5.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 2948.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.1 1.1 0.2 0.0 0.0 0.1 1.2 0.0 0.1 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.7 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.2 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 1.5 0.0 0.3 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.0 0.0 0.0 42.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 1.4 27.5 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 19404.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 2.3 0.0 0.1 0.3 IGHV4-28 ENSG00000211952 "Immunoglobulin heavy variable 4-28" A0A0C4DH34 14 106324254-106324760 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 44.8;lymphoid tissue: 87.4;salivary gland: 39.9;stomach 1: 30.7;urinary bladder: 122.6" "Cell type enriched" "Detected in some" 230 "Plasma cells: 346.4" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "spinal cord: 1.3" "Group enriched" "Detected in some" 206 "memory B-cell: 28.7;naive B-cell: 12.5" "Lineage enriched" "Detected in single" 288 "B-cells: 28.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 2500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.14e-3)" "unprognostic (1.32e-2)" "unprognostic (8.05e-2)" "unprognostic (6.64e-3)" "prognostic favorable (2.63e-4)" "unprognostic (1.58e-2)" "unprognostic (7.52e-2)" "unprognostic (1.03e-1)" "unprognostic (5.74e-2)" "unprognostic (4.76e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (4.79e-6)" "unprognostic (1.45e-1)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-1)" 1.8 11.3 0.0 40.9 0.0 6.0 12.9 0.0 0.2 3.3 0.1 44.8 44.8 1.0 0.0 12.5 1.9 7.7 1.2 0.0 0.0 1.8 2.4 8.9 10.0 0.0 0.0 3.5 0.4 0.0 0.2 0.0 0.0 0.8 44.1 0.0 39.9 1.7 0.0 0.5 30.2 2.0 1.3 42.3 30.7 0.5 0.0 5.8 4.3 0.0 87.4 122.6 1.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.7 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGHV4-31 ENSG00000231475 "Immunoglobulin heavy variable 4-31" A0A087WSY4 14 106349283-106349792 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467.7;urinary bladder: 190.8" "Cell type enriched" "Detected in some" 183 "Plasma cells: 1651.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "spinal cord: 1.6" "Group enriched" "Detected in some" 48 "memory B-cell: 43.6;naive B-cell: 19.4" "Lineage enriched" "Detected in single" 66 "B-cells: 43.6" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.4;SH-SY5Y: 1.0" "Immunoglobulin genes" NA NA 710000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.53e-3)" "unprognostic (9.05e-2)" "unprognostic (1.12e-1)" "prognostic favorable (5.74e-4)" "prognostic favorable (4.64e-5)" "unprognostic (1.16e-2)" "unprognostic (2.22e-1)" "unprognostic (1.04e-1)" "unprognostic (5.05e-2)" "unprognostic (1.72e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (2.00e-1)" "unprognostic (1.48e-1)" "unprognostic (3.63e-1)" "unprognostic (1.09e-1)" 4.3 1.7 0.0 48.0 0.0 5.4 37.6 0.0 0.3 15.4 0.0 103.8 72.1 6.5 1.5 32.2 5.3 105.2 11.7 0.0 0.7 3.9 6.3 19.1 104.0 0.2 0.2 58.0 4.7 0.2 0.5 0.0 0.1 11.4 24.9 0.0 53.2 8.4 0.1 1.3 90.4 3.1 1.6 138.6 87.8 1.3 0.2 76.0 15.7 0.0 467.7 190.8 4.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.1 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.7 0.2 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1651.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-34 ENSG00000211956 "Immunoglobulin heavy variable 4-34" P06331 14 106373663-106374145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 283.3;urinary bladder: 278.5" "Cell type enriched" "Detected in some" 197 "Plasma cells: 15696.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 602 "U-698: 5353.4" "Immunoglobulin genes" NA NA 4300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.34e-3)" "unprognostic (1.32e-1)" "unprognostic (2.25e-2)" "unprognostic (5.34e-3)" "unprognostic (6.12e-2)" "prognostic favorable (2.77e-4)" "unprognostic (8.06e-2)" "unprognostic (3.89e-1)" "unprognostic (1.23e-1)" "unprognostic (4.27e-2)" "unprognostic (2.68e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.55e-6)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (7.51e-2)" 7.9 3.0 0.0 0.0 0.3 0.0 9.8 0.1 1.5 12.0 0.1 83.5 0.0 5.5 0.9 7.3 22.5 0.0 2.3 0.0 0.2 7.2 7.0 33.4 0.0 0.6 0.2 22.0 1.3 0.4 0.9 0.3 0.3 3.8 2.2 0.0 82.1 0.0 0.3 2.8 54.2 0.3 0.1 283.3 48.0 0.3 0.1 0.0 19.3 0.0 0.0 278.5 4.0 1.4 3.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.5 2.6 3.2 0.0 0.0 1.4 0.0 4.1 0.0 0.3 0.0 0.6 3.7 0.0 0.1 8.8 0.4 1.8 0.0 0.8 5353.4 0.0 3.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.1 0.5 0.0 0.8 0.0 0.3 0.1 1.5 0.0 0.2 0.6 0.2 0.3 0.1 0.1 1.4 0.0 0.0 0.0 0.0 79.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15696.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 5.6 0.0 0.0 0.0 IGHV4-39 ENSG00000211959 "Immunoglobulin heavy variable 4-39" P01824 14 106421711-106422218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 251.6;lymphoid tissue: 474.9;salivary gland: 247.1;urinary bladder: 541.3" "Cell type enriched" "Detected in some" 432 "Plasma cells: 48104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.6;naive B-cell: 1.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 2.3;Daudi: 1.8;HL-60: 2.4;NB-4: 2.2;RH-30: 2.1;RPMI-8226: 1.4;U-266/70: 2.1;U-698: 2.0" "Immunoglobulin genes" NA NA 5000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.18e-3)" "unprognostic (2.99e-3)" "unprognostic (5.95e-3)" "unprognostic (1.46e-2)" "unprognostic (5.65e-2)" "unprognostic (2.38e-3)" "unprognostic (4.48e-2)" "unprognostic (2.63e-1)" "unprognostic (1.77e-1)" "unprognostic (2.23e-2)" "unprognostic (2.35e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (2.04e-2)" "unprognostic (2.77e-1)" "unprognostic (7.68e-2)" "unprognostic (8.33e-2)" 17.8 6.5 0.5 378.0 0.5 14.5 33.2 0.1 0.8 24.0 1.5 251.6 4.4 12.5 2.5 19.1 17.7 0.0 11.4 0.1 0.2 13.8 13.8 54.9 0.0 0.8 1.2 17.6 3.7 1.2 1.4 0.0 0.6 7.1 5.0 0.0 247.1 9.5 0.5 12.1 143.6 2.0 0.1 474.9 108.1 1.3 0.4 2.8 37.2 0.0 5.3 541.3 13.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 1.1 2.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.2 0.2 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.2 1.6 0.1 0.1 0.1 1.7 0.5 0.1 1.1 0.1 0.1 0.2 0.1 0.0 0.5 0.5 0.1 0.8 0.1 0.2 0.8 1.2 0.6 0.1 0.4 0.3 0.0 0.0 0.0 0.0 89.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 111.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48104.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.3 0.0 IGHV4-4 ENSG00000276775 "Immunoglobulin heavy variable 4-4" A0A075B6R2 14 106011922-106012420 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 567.7;urinary bladder: 768.4" "Cell type enriched" "Detected in some" 285 "Plasma cells: 2624.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 10 "midbrain: 4.8" "Group enriched" "Detected in some" 23 "memory B-cell: 56.6;naive B-cell: 31.2" "Lineage enriched" "Detected in many" 30 "B-cells: 56.6" "Cell line enriched" "Detected in some" 18 "Karpas-707: 34.5" "Immunoglobulin genes" NA NA 3800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-3)" "unprognostic (1.93e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.60e-6)" "unprognostic (2.24e-1)" "unprognostic (6.27e-2)" "unprognostic (1.30e-1)" "unprognostic (2.10e-1)" "unprognostic (7.45e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (3.16e-1)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (2.05e-1)" 9.4 2.5 0.0 131.4 0.0 17.8 63.6 0.0 0.2 37.5 0.1 205.2 159.9 3.8 0.8 59.8 53.4 104.9 0.9 0.0 0.1 5.5 6.6 36.9 173.2 0.3 4.8 10.0 6.0 0.4 0.4 0.0 0.1 4.0 140.2 0.0 78.2 15.0 0.3 3.8 78.6 13.4 0.4 186.4 175.0 1.6 0.1 31.8 16.7 0.0 567.7 768.4 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 34.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 56.6 0.2 0.2 0.0 31.2 0.6 0.0 0.0 0.0 0.0 1.9 0.6 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.3 4.8 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2624.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 IGHV4-59 ENSG00000224373 "Immunoglobulin heavy variable 4-59" P01825 14 106627249-106627825 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 525.9;lymphoid tissue: 911.2;urinary bladder: 702.5" "Cell type enriched" "Detected in some" 301 "Plasma cells: 12374.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "spinal cord: 2.0" "Group enriched" "Detected in some" 37 "memory B-cell: 169.0;naive B-cell: 77.2" "Lineage enriched" "Detected in many" 51 "B-cells: 169.0" "Cell line enhanced" "Detected in some" "MOLT-4: 8.1;SCLC-21H: 2.0;SH-SY5Y: 4.2" "Immunoglobulin genes" NA NA 5500000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.62e-5)" "unprognostic (3.95e-2)" "unprognostic (7.25e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-2)" "prognostic favorable (9.18e-5)" "unprognostic (2.88e-2)" "unprognostic (3.55e-1)" "unprognostic (2.16e-1)" "unprognostic (3.22e-2)" "unprognostic (2.22e-1)" "unprognostic (3.68e-1)" "prognostic unfavorable (1.41e-7)" "unprognostic (6.04e-2)" "unprognostic (2.24e-1)" "unprognostic (1.94e-1)" "unprognostic (1.76e-1)" 23.9 3.2 0.0 260.5 0.3 95.5 89.3 0.0 1.1 40.4 0.8 525.9 301.0 12.1 2.7 89.6 17.9 168.0 27.9 0.0 0.6 13.8 20.6 89.9 148.0 0.3 0.1 23.5 10.3 1.7 1.5 0.3 0.2 12.6 456.0 0.0 225.7 8.8 0.5 3.6 222.6 19.5 2.0 465.3 260.5 15.0 0.2 86.4 44.1 0.0 911.2 702.5 10.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.8 0.0 0.0 0.0 8.1 1.0 0.3 0.3 0.0 0.8 1.0 0.7 0.0 0.0 2.0 4.2 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.4 0.4 0.1 1.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 169.0 0.0 0.2 1.4 77.2 0.1 0.0 0.0 0.0 0.1 3.3 0.1 11.9 0.0 0.3 0.0 1.1 0.0 0.6 0.3 0.1 0.2 2.0 0.2 0.3 0.0 0.0 0.6 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 11.2 0.0 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 12374.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 3.6 0.0 0.5 0.0 IGHV4-61 ENSG00000211970 "Immunoglobulin heavy variable 4-61" A0A0C4DH41 14 106639119-106639657 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 206.7;lymphoid tissue: 385.2;stomach 1: 143.1" "Cell type enriched" "Detected in some" 98 "Plasma cells: 2432.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 25.5" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Cell line enriched" "Detected in single" 11 "MOLT-4: 8.7" "Immunoglobulin genes" NA NA 4400000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (2.11e-3)" "unprognostic (6.59e-2)" "unprognostic (4.92e-2)" "unprognostic (1.12e-2)" "prognostic favorable (3.71e-6)" "unprognostic (6.96e-2)" "unprognostic (5.98e-2)" "unprognostic (1.26e-1)" "unprognostic (1.72e-2)" "unprognostic (9.95e-2)" "unprognostic (9.02e-2)" "prognostic unfavorable (4.13e-6)" "unprognostic (3.55e-2)" "unprognostic (3.10e-1)" "unprognostic (4.24e-1)" "unprognostic (2.32e-2)" 6.4 44.4 0.0 97.5 0.1 30.8 56.0 0.0 0.2 10.1 0.1 206.7 185.7 5.8 0.0 15.5 5.0 22.4 3.1 0.0 0.1 5.5 10.5 28.2 54.4 0.3 0.1 10.4 1.3 0.2 0.7 0.0 0.3 4.1 121.8 0.0 104.3 7.0 0.2 0.7 86.5 8.0 0.3 181.3 143.1 0.9 0.0 30.1 23.0 0.0 385.2 43.9 5.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.0 0.0 8.7 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.1 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 4.6 0.0 0.1 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2432.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 IGHV5-51 ENSG00000211966 "Immunoglobulin heavy variable 5-51" A0A0C4DH38 14 106578744-106579236 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 245.7;lymphoid tissue: 547.1;salivary gland: 224.5;urinary bladder: 353.3" "Cell type enriched" "Detected in some" 87 "Plasma cells: 5993.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.8;Daudi: 3.7;K-562: 2.4;NB-4: 1.7;TIME: 3.3" HPA006014 Approved "Immunoglobulin genes" NA NA 2700000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA006014: " "unprognostic (2.03e-3)" "unprognostic (1.00e-1)" "unprognostic (3.21e-2)" "unprognostic (7.65e-3)" "unprognostic (1.80e-2)" "prognostic favorable (5.47e-4)" "unprognostic (2.40e-2)" "unprognostic (1.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.47e-2)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.31e-7)" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.70e-1)" "unprognostic (1.17e-1)" 20.0 4.8 0.3 0.0 0.0 0.0 25.9 0.1 1.7 17.8 0.7 245.7 0.0 8.6 6.3 19.1 15.2 27.1 2.1 0.1 0.7 15.4 15.0 56.2 0.0 0.9 0.0 8.8 17.1 1.0 2.2 0.6 0.2 11.2 0.0 0.0 224.5 0.0 0.7 3.2 144.8 1.7 0.6 547.1 99.9 4.8 0.1 0.0 25.6 0.0 0.0 353.3 14.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.3 1.3 1.2 0.8 0.0 0.1 0.0 0.7 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 1.7 0.1 0.7 0.9 0.0 0.2 0.6 0.1 1.3 0.0 0.0 0.0 0.0 68.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 44.9 0.0 0.0 0.0 0.7 1.0 0.1 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5993.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 IGHV6-1 ENSG00000211933 "Immunoglobulin heavy variable 6-1" A0A0B4J1U7 14 105939756-105940253 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 441.3;lymphoid tissue: 159.0" "Cell type enriched" "Detected in some" 175 "Plasma cells: 2295.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "naive B-cell: 19.7" "Lineage enriched" "Detected in single" 53 "B-cells: 19.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 930000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.35e-4)" "unprognostic (9.66e-2)" "unprognostic (4.55e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.85e-5)" "unprognostic (1.84e-1)" "unprognostic (2.13e-2)" "unprognostic (1.89e-3)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.48e-6)" "unprognostic (3.69e-2)" "unprognostic (6.93e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" 13.0 2.1 0.3 0.0 0.1 0.0 7.5 0.0 0.4 4.2 0.2 441.3 0.0 1.2 0.0 17.9 4.3 1.5 2.7 0.0 0.1 3.2 6.2 13.6 0.0 0.3 0.1 0.9 11.5 0.0 0.3 0.0 0.1 1.6 0.0 0.0 56.7 8.6 0.1 2.0 40.9 11.2 0.3 159.0 19.5 0.3 0.2 0.0 6.8 0.0 0.0 3.7 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.1 19.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.0 0.1 0.3 0.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.1 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2295.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGSF21 "MGC15730, RP11-121A23.1" ENSG00000117154 "Immunoglobin superfamily member 21" Q96ID5 1 18107798-18378483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.7" "Group enriched" "Detected in some" 4 "Bipolar cells: 177.8;Excitatory neurons: 82.2;Microglial cells: 74.9;Oligodendrocyte precursor cells: 141.3" "Group enriched" "Detected in many" 5 "breast cancer: 4.1;glioma: 8.6;prostate cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 19.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 23000 "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.50e-3)" "unprognostic (7.06e-2)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.34e-2)" "unprognostic (2.33e-1)" "unprognostic (7.85e-4)" "unprognostic (3.76e-5)" "unprognostic (2.10e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-2)" 2.2 4.8 29.6 0.4 35.8 0.4 3.0 41.4 51.7 1.7 9.2 1.0 0.0 1.0 0.4 0.9 1.0 0.8 1.0 37.4 17.6 1.1 0.4 1.5 0.2 26.9 23.4 0.6 1.9 10.4 1.6 1.4 27.0 3.8 0.3 9.4 1.1 1.1 0.3 0.8 0.4 0.3 21.6 13.0 0.6 0.8 24.5 0.8 0.6 0.4 0.7 3.9 1.1 33.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.6 35.8 41.4 51.7 37.4 17.6 26.9 23.4 27.0 21.6 24.5 33.5 0.1 0.0 0.0 3.6 0.6 0.3 0.2 0.0 0.0 177.8 9.2 2.7 0.6 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 5.9 0.0 0.0 1.8 3.0 0.0 82.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.7 28.9 0.1 0.0 23.6 4.0 12.8 0.6 12.8 0.0 74.9 0.0 6.3 0.0 141.3 2.4 0.1 1.3 0.0 0.0 0.9 0.0 0.0 0.0 13.0 6.6 4.5 0.2 0.4 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 IL2RA "CD25, IDDM10, IL2R" ENSG00000134460 "Interleukin 2 receptor subunit alpha" P01589 10 6010689-6062370 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.9;lymphoid tissue: 17.4;urinary bladder: 11.2" "Group enriched" "Detected in some" 6 "granulocytes: 80.8;monocytes: 177.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 175.9;T-reg: 248.0" "Group enriched" "Detected in many" 14 "granulocytes: 175.9;T-cells: 248.0" "Cell line enriched" "Detected in some" 59 "HDLM-2: 1113.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB002419, HPA054622" Enhanced NA NA 410000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "CAB002419: AB_563538, HPA054622: AB_2682546" "unprognostic (2.82e-1)" "unprognostic (8.10e-3)" "unprognostic (1.75e-2)" "unprognostic (5.86e-2)" "unprognostic (1.50e-1)" "unprognostic (1.45e-3)" "unprognostic (2.78e-2)" "unprognostic (2.73e-1)" "unprognostic (5.03e-2)" "unprognostic (6.32e-2)" "unprognostic (7.21e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.08e-9)" "unprognostic (2.10e-2)" "unprognostic (4.66e-2)" "unprognostic (2.22e-1)" "unprognostic (5.10e-2)" 18.9 1.9 0.0 14.2 0.0 0.4 1.4 0.1 0.2 0.5 1.1 3.3 1.9 0.5 0.2 2.6 0.3 2.9 0.8 0.1 0.1 0.7 0.5 2.4 17.4 0.5 0.1 0.1 0.5 0.3 0.9 2.5 0.4 0.4 2.1 0.0 0.5 0.8 0.1 0.4 6.5 4.7 0.1 7.5 1.2 0.2 0.2 5.2 1.3 0.6 12.9 11.2 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1113.3 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 0.4 18.9 0.0 0.3 0.0 175.9 0.1 20.1 0.6 0.0 2.2 14.7 27.3 3.1 0.2 7.3 2.0 0.2 0.9 13.4 0.3 0.2 248.0 3.2 0.0 0.0 0.1 0.2 0.1 0.1 0.5 0.1 0.4 0.1 0.2 0.2 0.4 0.0 1.8 1.0 13.0 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.0 0.0 0.0 8.3 0.0 0.0 0.1 0.2 0.2 0.6 0.4 0.0 0.8 0.2 0.6 0.0 0.7 1.1 0.1 80.8 0.0 0.4 0.2 0.3 0.0 0.2 0.0 0.0 7.7 4.8 0.1 0.0 19.3 3.6 1.9 177.6 0.0 2.1 0.0 0.3 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.1 0.6 0.0 19.6 0.0 0.1 0.2 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 ILDR1 "DFNB42, MGC50831" ENSG00000145103 "Immunoglobulin like domain containing receptor 1" Q86SU0 3 121987323-122022247 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Club cells: 14.7;Collecting duct cells: 20.2;Cytotrophoblasts: 16.6;Distal enterocytes: 17.5;Glandular and luminal cells: 13.5;Respiratory ciliated cells: 13.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 4 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.3;HDLM-2: 8.2;MCF7: 5.1;RT4: 7.5;T-47d: 5.3;U-266/70: 6.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA018207 Approved "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA018207: AB_1851742" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (9.24e-2)" "unprognostic (4.46e-3)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (1.65e-2)" "unprognostic (2.80e-2)" "unprognostic (2.00e-1)" "unprognostic (2.04e-1)" "unprognostic (7.78e-2)" "unprognostic (2.37e-1)" "prognostic favorable (5.79e-9)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (3.25e-3)" "unprognostic (2.21e-2)" 0.0 0.7 0.2 1.3 0.1 0.3 2.9 0.2 0.3 11.7 0.1 8.2 3.3 1.0 12.8 3.8 5.1 3.3 0.0 0.1 0.0 6.5 0.2 2.9 1.1 0.1 0.1 0.0 6.7 15.7 2.4 1.8 0.1 6.9 7.2 0.2 8.0 10.6 0.1 1.2 2.4 0.3 0.0 0.6 0.8 0.6 0.1 0.8 7.3 0.0 2.2 2.2 1.1 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 6.3 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 8.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.1 0.0 0.1 0.0 1.2 0.0 0.0 0.0 2.4 2.8 7.5 0.2 0.0 0.0 0.7 0.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 6.1 1.4 1.1 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.2 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 12.8 7.4 0.3 1.3 0.0 0.8 7.5 0.0 0.0 4.2 2.4 0.7 4.3 14.7 20.2 0.0 16.6 0.1 17.5 1.9 7.5 0.2 6.3 1.6 0.1 3.5 0.0 0.5 3.7 0.5 0.1 1.1 13.5 0.0 0.2 0.0 0.1 1.2 0.0 0.5 7.9 8.2 0.6 0.0 0.0 0.0 0.3 1.8 1.9 0.0 0.0 0.0 0.0 0.2 2.6 8.9 0.0 2.1 2.2 2.5 2.1 13.7 0.0 0.0 0.0 0.6 0.0 0.1 5.9 0.6 5.1 0.1 0.0 7.8 3.5 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81656914-81686331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved NA No 310000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 12.8 11.3 12.7 12.7 13.3 27.0 10.2 11.8 15.8 8.9 14.8 26.9 23.5 10.4 11.7 20.7 11.8 11.8 25.8 14.6 12.6 16.4 31.3 10.2 17.6 10.9 13.4 13.5 8.6 15.5 10.1 8.2 13.0 11.0 28.4 18.2 8.3 8.1 14.1 5.1 23.2 18.0 12.4 11.2 14.7 38.2 12.1 19.6 21.8 29.0 16.3 14.0 10.5 15.1 12.5 34.6 23.3 17.2 14.0 21.9 9.8 35.7 26.5 31.3 36.7 16.3 20.1 47.2 27.5 26.2 45.6 9.4 27.1 12.0 41.3 50.7 26.5 35.7 19.2 20.8 23.8 36.7 35.0 20.3 17.6 24.9 48.2 30.2 35.2 35.6 32.8 38.7 30.6 8.7 46.1 18.4 10.1 32.2 37.2 21.2 16.9 19.2 31.7 43.5 9.3 38.7 23.9 6.2 41.3 39.6 20.4 27.4 26.4 24.9 32.8 19.8 44.1 45.2 58.5 67.4 29.4 20.7 35.9 50.5 6.6 29.4 13.6 10.3 16.8 20.3 13.5 14.9 7.5 13.7 14.0 16.8 11.2 20.5 11.8 12.0 19.6 9.5 12.7 13.3 11.8 15.8 14.6 12.6 10.9 13.4 13.0 12.4 12.1 15.1 22.2 16.0 12.7 15.3 25.7 13.8 16.9 16.8 28.5 15.8 8.5 6.9 38.3 21.5 17.3 9.2 14.6 9.7 29.4 54.4 31.3 16.2 4.0 23.2 19.7 16.5 21.5 11.6 19.4 20.3 11.0 16.1 12.2 17.3 33.0 11.5 13.9 32.9 14.3 25.2 12.5 19.8 18.3 16.2 13.1 8.2 15.5 16.4 12.4 12.2 21.9 23.4 13.4 14.1 14.0 19.0 62.3 15.1 18.1 14.4 30.4 30.7 25.1 15.9 13.1 15.5 17.0 78.4 19.2 26.9 8.7 3.0 26.2 18.7 22.3 21.3 IMPACT RWDD5 ENSG00000154059 "Impact RWD domain protein" Q9P2X3 18 24426634-24453531 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Stress response, Translation regulation" "Actin-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 65.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 65.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041045, HPA041968" Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA041045: AB_10793866, HPA041968: AB_10795603" "unprognostic (1.13e-1)" "unprognostic (8.59e-2)" "unprognostic (1.15e-2)" "unprognostic (1.62e-1)" "unprognostic (5.12e-2)" "unprognostic (7.94e-2)" "unprognostic (3.29e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-2)" "unprognostic (2.15e-1)" "unprognostic (8.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (7.90e-4)" "unprognostic (5.60e-3)" "unprognostic (9.27e-2)" "unprognostic (1.99e-3)" "unprognostic (5.60e-3)" 19.3 21.0 10.1 12.0 11.5 15.8 25.1 11.2 10.4 15.5 9.6 18.0 16.1 16.4 18.9 21.7 14.2 12.7 19.3 8.6 18.1 24.4 22.3 15.7 11.5 12.2 14.7 17.1 20.5 27.8 10.0 15.0 12.2 18.0 14.9 10.1 25.0 16.0 20.3 11.4 16.5 13.0 12.2 15.2 15.9 34.5 21.9 11.2 32.5 13.1 12.0 12.7 8.0 12.5 27.8 15.6 26.4 33.0 25.2 37.8 43.1 36.4 43.1 20.1 19.9 5.4 23.8 16.7 35.8 38.9 12.4 31.9 9.1 40.3 29.7 0.1 8.2 24.9 14.9 8.8 38.0 99.0 23.1 33.0 30.6 13.4 82.1 24.2 38.7 0.0 21.2 0.2 33.6 25.6 0.2 17.5 44.0 48.8 17.1 0.1 51.6 8.4 22.0 43.2 21.8 26.9 51.6 22.6 37.7 20.8 31.9 33.2 48.0 80.5 10.4 15.3 15.6 31.0 43.0 0.3 32.4 12.3 35.5 65.8 9.6 18.4 4.2 12.2 5.6 4.0 5.5 4.1 12.3 5.3 5.6 4.7 1.5 9.0 9.0 8.5 8.0 6.0 10.1 11.5 11.2 10.4 8.6 18.1 12.2 14.7 12.2 12.2 21.9 12.5 20.8 19.2 14.9 11.1 10.9 11.3 11.5 23.5 18.2 11.3 34.6 26.0 30.4 17.2 22.9 14.7 2.1 30.7 11.0 10.8 37.2 19.5 17.2 21.2 24.2 18.8 15.6 23.3 7.6 22.4 20.2 20.1 16.8 13.7 20.3 43.3 15.0 33.5 26.4 5.0 13.7 25.6 26.4 19.8 10.4 21.0 16.1 21.6 19.6 5.6 25.3 41.7 7.2 10.1 9.9 20.2 7.1 27.1 11.1 15.1 17.3 47.8 25.4 11.0 13.1 15.3 21.0 83.9 75.6 27.0 14.5 16.4 10.3 52.5 21.9 10.2 INA "NEF5, NF-66" ENSG00000148798 "Internexin neuronal intermediate filament protein alpha" Q16352 10 103277138-103290346 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 160.7;pituitary gland: 41.4;retina: 97.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 62.4;Cone photoreceptor cells: 22.9;Early spermatids: 41.4;Excitatory neurons: 28.7;Horizontal cells: 45.4;Inhibitory neurons: 39.8;Late spermatids: 26.5;Rod photoreceptor cells: 48.2;Spermatocytes: 20.3" "Group enriched" "Detected in many" 4 "glioma: 4.7;testis cancer: 18.2;urothelial cancer: 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 53.0;SCLC-21H: 103.3;SH-SY5Y: 58.7;SiHa: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002059, HPA007572, HPA008057" Enhanced Supported Approved "Intermediate filaments,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Intermediate filaments" Cytosol "CAB002059: AB_442031, HPA007572: , HPA008057: AB_1851833" "unprognostic (1.77e-1)" "unprognostic (2.50e-2)" "unprognostic (9.54e-2)" "unprognostic (5.49e-3)" "unprognostic (3.91e-1)" "unprognostic (1.45e-3)" "unprognostic (1.31e-1)" "unprognostic (2.29e-2)" "unprognostic (2.08e-2)" "unprognostic (1.98e-1)" "unprognostic (8.09e-3)" "unprognostic (3.07e-2)" "unprognostic (1.78e-3)" "unprognostic (1.66e-1)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (1.07e-1)" 0.2 12.1 34.2 1.2 35.5 0.0 0.0 63.3 160.7 0.0 0.0 3.3 0.6 0.0 0.0 0.6 0.0 0.1 0.0 31.8 109.5 0.0 0.0 0.2 0.1 107.9 37.5 0.0 2.0 0.4 41.4 0.1 98.1 0.2 1.2 97.3 0.1 0.0 0.0 0.8 1.1 0.8 25.3 0.0 1.1 2.7 72.8 1.7 0.1 0.0 0.2 1.1 0.5 51.9 0.0 25.4 11.8 0.0 0.1 0.0 19.3 13.3 3.3 3.1 0.3 0.0 0.0 0.0 5.4 0.9 1.5 1.9 11.0 0.0 0.7 24.6 4.9 0.0 6.8 0.1 0.2 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 13.6 0.0 53.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 103.3 58.7 71.6 0.1 0.0 2.7 0.0 0.7 0.1 0.0 0.1 0.0 0.0 3.4 3.1 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.2 35.5 63.3 160.7 31.8 109.5 107.9 37.5 98.1 25.3 72.8 51.9 0.1 0.0 0.0 6.2 0.0 0.3 0.1 0.0 0.0 62.4 0.0 0.4 0.5 0.0 0.0 0.0 22.9 0.2 0.0 0.1 0.0 0.1 41.4 0.4 0.2 0.9 7.8 0.0 28.7 0.0 0.2 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.5 45.4 39.8 0.0 0.0 0.0 0.0 26.5 0.3 0.1 0.0 2.8 0.0 8.7 0.0 1.0 5.4 0.4 0.0 0.4 0.0 0.5 0.0 0.0 0.0 48.2 0.0 0.0 0.6 20.3 4.1 1.0 0.4 0.1 0.1 0.1 0.0 0.6 INIP "C9orf80, HSPC043, hSSBIP1, MISE, SOSS-C" ENSG00000148153 "INTS3 and NABP interacting protein" Q9NRY2 9 112683926-112718149 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020382 Approved Supported Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA020382: AB_1845840" "prognostic unfavorable (7.08e-4)" "unprognostic (1.67e-1)" "unprognostic (9.64e-2)" "unprognostic (2.35e-1)" "unprognostic (8.05e-2)" "unprognostic (8.56e-2)" "unprognostic (1.01e-2)" "unprognostic (6.29e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.11e-2)" "unprognostic (4.47e-3)" "prognostic favorable (2.00e-8)" "prognostic favorable (2.53e-4)" "unprognostic (2.28e-1)" "unprognostic (3.50e-2)" "unprognostic (1.26e-1)" 7.4 8.7 8.0 8.4 10.9 10.4 11.4 9.7 11.9 8.0 5.4 10.1 10.3 7.2 8.6 9.8 8.4 8.6 7.5 8.1 9.6 10.8 11.0 8.4 14.5 9.2 8.8 8.2 5.0 10.7 6.5 6.1 9.6 6.9 11.5 10.3 8.1 6.5 6.5 9.2 10.9 7.6 8.4 9.7 7.4 5.4 9.6 14.5 10.6 10.0 14.1 9.3 6.2 15.5 16.5 15.6 21.4 31.0 18.2 19.2 21.9 22.7 12.4 19.4 19.3 19.7 13.2 43.8 13.9 15.7 14.6 22.9 21.0 10.9 25.8 53.0 12.3 18.2 17.6 18.0 11.8 37.1 13.3 10.4 14.7 20.6 16.6 9.5 18.2 22.1 31.7 27.5 21.4 27.8 33.3 19.0 11.1 29.8 28.8 36.5 45.1 18.9 22.2 21.9 27.9 20.9 28.7 18.1 15.7 14.2 27.1 23.1 15.4 16.1 24.7 30.9 22.4 13.7 62.4 37.3 20.4 21.3 27.7 30.4 24.8 32.5 15.7 29.3 20.7 15.5 20.1 23.4 27.1 20.0 21.8 18.9 19.8 18.4 27.0 9.7 20.8 20.3 8.0 10.9 9.7 11.9 8.1 9.6 9.2 8.8 9.6 8.4 9.6 15.5 15.6 22.4 15.6 9.1 19.1 36.7 18.1 31.4 13.1 17.1 19.2 16.5 15.5 15.7 22.4 14.7 16.7 21.4 20.6 19.4 56.7 23.4 3.9 21.0 18.8 18.1 22.3 19.4 18.3 16.1 32.0 14.9 12.8 18.7 26.6 11.2 15.7 17.7 26.1 43.7 15.4 17.1 32.6 24.5 33.5 3.2 14.0 26.2 19.6 3.7 42.3 24.7 34.0 16.6 25.2 24.2 12.3 12.0 11.8 17.9 21.7 31.7 13.0 16.9 0.0 17.3 13.1 17.4 15.8 19.4 41.8 14.8 23.0 12.4 19.8 25.2 INPP5K SKIP ENSG00000132376 "Inositol polyphosphate-5-phosphatase K" Q9BT40 17 1494577-1516742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Congenital muscular dystrophy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 96.1;Late spermatids: 345.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (7.47e-2)" "prognostic favorable (3.91e-4)" "unprognostic (8.91e-2)" "prognostic favorable (2.33e-5)" "unprognostic (3.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.50e-1)" "unprognostic (7.50e-2)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic favorable (1.47e-6)" "unprognostic (4.71e-2)" "unprognostic (9.35e-3)" "unprognostic (3.01e-2)" "unprognostic (7.20e-2)" "unprognostic (4.28e-3)" "unprognostic (1.04e-1)" 34.7 15.2 25.8 12.9 26.0 34.5 29.2 25.3 30.2 19.5 61.5 19.6 10.2 17.0 13.1 17.9 15.3 10.7 28.9 29.8 25.7 16.7 15.0 27.3 18.6 26.9 26.9 17.8 21.9 13.7 14.8 18.6 26.9 19.6 12.7 15.9 18.1 12.9 40.5 30.1 19.4 12.0 25.4 22.8 19.1 20.4 26.9 25.8 30.4 25.2 19.7 18.2 17.9 27.0 14.9 24.0 9.2 18.4 22.5 13.2 12.1 12.0 23.6 15.8 19.6 15.7 9.1 14.6 23.2 22.2 12.5 19.4 22.1 9.6 14.3 35.3 33.0 8.6 18.1 5.9 31.3 7.9 17.0 16.2 24.0 15.8 16.1 10.0 25.3 25.3 9.4 25.9 10.6 12.5 24.5 7.1 3.9 23.9 14.6 19.0 6.7 14.6 12.8 10.3 7.1 18.0 10.2 21.6 24.3 13.0 17.9 7.3 16.2 13.6 13.3 19.8 16.8 12.9 23.4 7.4 14.7 9.1 17.3 104.3 42.2 74.3 48.7 41.9 39.7 27.5 44.5 50.2 36.2 24.4 37.5 41.1 74.7 42.3 66.6 27.0 75.1 62.5 25.8 26.0 25.3 30.2 29.8 25.7 26.9 26.9 26.9 25.4 26.9 27.0 26.1 32.1 14.1 8.5 20.6 30.0 15.7 10.8 18.8 7.8 15.6 12.2 35.8 8.6 11.0 23.9 2.1 13.9 27.5 26.0 13.7 19.4 96.1 10.3 6.9 27.0 17.4 25.2 5.4 24.3 16.4 15.5 13.3 17.4 19.7 7.7 28.5 10.2 11.9 20.2 5.9 17.3 14.2 18.4 19.0 345.7 11.5 13.8 32.0 2.8 37.1 23.1 27.8 2.5 7.0 27.1 23.4 7.5 18.0 13.3 33.2 11.2 6.4 7.9 19.7 12.6 15.3 35.5 20.4 18.1 30.3 31.1 27.2 5.8 13.5 17.4 INSM1 "IA-1, IA1" ENSG00000173404 "INSM transcriptional repressor 1" Q01101 20 20368104-20370949 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.4;pituitary gland: 29.2" "Cell type enriched" "Detected in some" 42 "Enteroendocrine cells: 506.7" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 370.4" "Low region specificity" "Detected in many" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "unprognostic (1.86e-2)" "unprognostic (5.25e-4)" "unprognostic (7.59e-2)" "unprognostic (3.49e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-3)" "unprognostic (4.34e-2)" "unprognostic (2.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-3)" "unprognostic (1.33e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (5.23e-1)" "unprognostic (1.22e-1)" 0.2 7.1 2.4 0.6 5.9 0.0 0.0 13.4 3.1 0.0 0.0 1.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.6 0.0 0.0 0.0 0.5 0.9 2.5 0.0 2.9 0.0 29.2 0.0 1.5 0.2 1.8 0.1 0.0 0.2 0.0 0.1 2.1 0.0 0.4 0.2 5.1 0.4 3.3 2.8 0.0 0.0 0.3 0.1 0.0 2.1 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.1 3.2 19.4 0.0 0.0 370.4 0.3 0.0 0.3 0.0 1.1 0.9 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 5.9 13.4 3.1 2.5 4.6 0.9 2.5 1.5 0.4 3.3 2.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.9 0.0 0.0 0.2 0.1 0.1 506.7 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.4 10.8 0.0 0.0 0.7 0.0 0.0 0.2 3.6 0.0 11.9 0.0 0.0 0.5 3.1 1.5 2.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 2.1 0.0 IPP KLHL27 ENSG00000197429 "Intracisternal A particle-promoted polypeptide" Q9Y573 1 45694324-45750653 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075545 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA075545: " "unprognostic (8.45e-3)" "unprognostic (1.35e-1)" "prognostic favorable (9.11e-4)" "unprognostic (1.63e-1)" "unprognostic (2.87e-1)" "unprognostic (5.84e-3)" "prognostic unfavorable (2.27e-4)" "unprognostic (2.99e-1)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.77e-1)" "unprognostic (7.03e-2)" "prognostic favorable (1.11e-4)" "unprognostic (2.68e-2)" "unprognostic (6.44e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-1)" 5.5 4.4 3.2 3.8 4.7 3.4 6.1 3.9 2.9 4.8 3.7 5.6 4.9 6.5 5.3 6.3 6.5 5.0 7.0 2.6 4.1 7.1 6.8 4.3 4.4 3.5 3.9 7.5 6.6 9.5 2.2 4.0 3.7 7.1 5.7 7.4 5.7 6.4 14.3 5.0 5.3 5.6 3.7 3.8 5.0 10.2 3.6 6.6 9.7 9.0 4.9 3.8 2.8 4.9 9.6 9.1 8.0 11.8 9.8 18.2 6.2 9.9 7.1 6.9 7.0 5.6 6.8 5.2 10.1 12.3 7.9 6.7 8.8 7.3 9.9 12.2 5.2 7.3 7.7 6.9 9.8 2.1 6.2 15.5 8.3 15.0 8.1 8.0 6.8 9.4 9.0 10.3 12.2 6.4 7.3 0.4 4.8 7.0 4.9 3.1 14.7 4.3 5.7 10.4 11.5 7.5 19.1 10.3 9.5 9.1 10.0 1.8 7.9 7.5 9.2 5.3 7.9 8.3 10.4 9.2 12.0 3.1 11.9 4.1 0.6 3.5 4.6 0.4 3.4 3.1 2.7 3.7 0.7 2.6 3.4 4.0 2.6 3.7 0.8 0.6 4.7 2.5 3.2 4.7 3.9 2.9 2.6 4.1 3.5 3.9 3.7 3.7 3.6 4.9 7.6 12.8 10.0 11.1 7.9 2.5 5.6 7.6 6.8 12.4 6.5 4.8 18.8 5.7 8.1 5.5 12.5 7.8 4.7 10.1 3.9 6.5 26.0 10.7 10.1 5.2 5.4 3.0 5.4 7.3 6.9 9.6 9.7 6.7 12.7 15.9 3.3 5.9 1.4 18.5 7.1 6.8 6.1 1.3 1.1 7.6 7.2 2.8 1.8 4.7 3.4 19.0 18.6 6.0 11.9 5.8 4.6 6.4 7.4 3.9 9.5 8.4 10.1 16.8 0.0 14.0 9.3 40.8 14.7 6.7 4.7 7.7 8.4 23.5 5.8 4.9 IQCA1 "DRC11, FLJ22527, IQCA" ENSG00000132321 "IQ motif containing with AAA domain 1" Q86XH1 2 236324147-236507535 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;choroid plexus: 22.7;thyroid gland: 19.2" "Cell type enhanced" "Detected in many" "Astrocytes: 180.9;Endometrial ciliated cells: 54.7;Respiratory ciliated cells: 115.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.3" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;HBEC3-KT: 3.3;HeLa: 3.8;hTERT-RPE1: 6.9;SuSa: 4.4;U-2 OS: 12.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.2" HPA057320 Uncertain Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 9: U-2 OS - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA057320: " "unprognostic (1.73e-2)" "unprognostic (6.38e-2)" "unprognostic (3.75e-3)" "unprognostic (1.62e-2)" "unprognostic (6.27e-3)" "unprognostic (1.73e-2)" "unprognostic (3.23e-5)" "unprognostic (1.55e-1)" "unprognostic (7.23e-3)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.62e-1)" "prognostic favorable (2.54e-4)" "unprognostic (1.19e-3)" "unprognostic (1.67e-3)" "unprognostic (1.91e-3)" "unprognostic (5.30e-2)" 2.2 1.2 23.3 0.4 25.3 0.0 1.8 18.1 46.0 1.3 22.7 0.2 0.1 1.7 5.4 0.7 11.0 1.7 0.5 21.2 21.1 4.6 0.1 2.7 0.4 20.8 27.0 2.4 1.3 1.4 10.3 0.2 19.7 1.5 0.1 2.2 1.2 1.3 0.0 0.2 0.3 0.5 13.9 3.1 0.5 4.5 22.2 2.8 19.2 0.0 0.6 1.7 1.0 16.7 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.2 0.0 0.1 0.3 0.1 0.0 0.0 3.2 0.0 1.0 0.0 0.0 3.3 0.0 0.0 0.1 0.0 3.8 0.0 0.1 0.0 0.0 0.2 1.7 0.0 0.0 6.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 12.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.2 0.3 1.3 0.0 0.4 0.0 0.0 0.0 0.0 23.3 25.3 18.1 46.0 21.2 21.1 20.8 27.0 19.7 13.9 22.2 16.7 2.8 16.0 12.6 180.9 0.4 0.5 7.8 26.9 1.8 26.2 1.7 14.1 1.3 11.5 26.7 3.7 16.7 0.5 0.0 0.0 0.0 10.8 24.0 54.7 5.2 10.4 0.0 0.0 26.0 1.5 5.6 3.3 0.5 9.8 1.3 6.7 2.2 0.0 0.3 0.0 11.6 0.0 16.2 0.0 0.0 14.5 2.1 0.4 0.0 9.4 0.0 0.5 1.0 4.5 2.4 1.2 0.0 6.0 0.3 1.7 0.0 11.7 115.7 2.3 0.0 0.8 2.2 31.0 28.3 0.8 0.3 0.3 0.8 1.9 0.0 3.1 IQCK "FLJ36575, MGC35048" ENSG00000174628 "IQ motif containing K" Q8N0W5 16 19716456-19858467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 128.3;Cone photoreceptor cells: 114.7;Respiratory ciliated cells: 98.7;Rod photoreceptor cells: 107.4;Spermatocytes: 101.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026792, HPA048786" Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear speckles" Cytosol "HPA026792: AB_1853889, HPA048786: AB_2680520" "unprognostic (4.21e-2)" "unprognostic (3.19e-1)" "unprognostic (6.29e-3)" "unprognostic (2.04e-2)" "unprognostic (3.70e-1)" "unprognostic (4.07e-2)" "unprognostic (1.69e-1)" "unprognostic (8.51e-2)" "unprognostic (1.58e-1)" "unprognostic (9.68e-3)" "unprognostic (1.17e-1)" "unprognostic (5.13e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "unprognostic (8.98e-2)" "unprognostic (6.51e-2)" "unprognostic (1.68e-1)" 3.8 2.7 5.3 1.3 5.7 0.5 5.9 5.2 6.8 7.5 8.7 2.6 3.8 4.6 15.4 1.6 20.2 5.7 3.5 5.1 8.7 8.7 2.1 4.0 1.5 6.2 7.2 6.5 3.6 19.4 6.3 3.2 5.7 3.4 2.9 11.0 6.4 7.6 3.0 2.1 1.6 3.8 6.8 1.8 3.9 18.2 5.6 1.6 16.8 2.9 1.1 4.1 2.0 8.0 2.6 6.8 8.7 5.7 2.6 8.1 0.5 0.0 4.4 4.0 3.1 0.4 4.8 0.3 4.7 2.4 2.5 3.0 1.9 3.3 2.8 1.1 1.8 0.1 1.9 3.4 8.2 1.6 0.0 4.7 2.7 5.4 1.2 4.5 4.4 4.2 2.8 0.8 2.5 8.5 1.6 0.9 2.6 2.8 6.4 5.3 0.8 0.4 10.0 1.8 8.1 3.4 3.9 1.2 5.3 1.6 3.6 0.9 3.1 1.1 0.9 4.6 0.9 0.1 0.6 0.0 5.4 0.2 1.9 0.0 0.3 0.0 0.5 1.3 0.9 0.5 0.5 0.8 0.1 0.2 1.0 0.5 0.0 0.0 1.3 0.3 0.5 0.3 5.3 5.7 5.2 6.8 5.1 8.7 6.2 7.2 5.7 6.8 5.6 8.0 42.4 16.0 5.1 128.3 1.7 6.1 9.7 16.4 9.6 54.1 18.3 16.5 0.7 24.3 17.8 46.0 114.7 4.9 1.3 8.6 46.9 47.2 57.2 76.9 19.0 22.1 5.4 0.8 31.9 29.6 2.8 11.8 12.8 14.9 0.0 6.2 11.7 2.1 6.0 3.3 45.9 4.3 32.6 2.4 3.9 34.8 18.0 3.7 17.8 15.0 1.5 26.3 0.0 37.2 53.4 29.8 2.2 18.0 2.3 7.3 2.0 32.5 98.7 107.4 6.6 7.5 15.6 101.7 35.8 3.9 5.1 4.1 3.0 18.1 6.7 5.1 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 11.2;Late spermatids: 26.6;Undifferentiated cells: 7.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: AB_10600108, HPA030143: AB_10601104" "unprognostic (9.99e-3)" "unprognostic (5.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.55e-3)" "unprognostic (1.52e-1)" "unprognostic (4.69e-3)" "prognostic unfavorable (8.94e-6)" "unprognostic (1.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.98e-1)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.30e-2)" "unprognostic (6.81e-2)" 0.7 0.7 0.2 2.2 0.4 15.5 0.6 0.0 0.6 1.1 0.2 4.1 6.6 0.5 1.1 5.2 0.2 0.7 0.4 0.5 0.1 0.6 0.6 1.6 1.6 0.9 0.4 0.1 0.2 0.1 0.1 2.8 0.9 0.4 5.0 0.0 1.0 0.1 0.3 3.7 5.7 2.9 0.0 0.8 4.6 3.8 0.6 3.4 0.2 0.0 2.2 0.9 2.1 0.4 59.2 28.4 25.6 18.1 1.6 4.0 12.4 43.1 28.3 41.0 36.6 32.4 52.5 5.2 15.6 25.2 21.6 54.6 17.5 22.1 36.3 0.1 15.7 7.8 62.6 16.1 0.2 9.7 0.1 1.2 2.5 34.3 50.0 10.0 24.1 12.5 16.1 8.1 30.2 31.2 5.7 13.7 18.6 57.7 28.0 18.9 28.8 6.1 10.4 20.3 16.3 25.2 38.7 44.9 14.9 29.8 35.8 25.6 16.8 36.8 43.7 30.4 51.4 4.0 2.1 2.4 12.4 15.1 42.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.2 0.4 0.0 0.6 0.5 0.1 0.9 0.4 0.9 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.4 1.3 0.1 0.4 0.6 0.0 1.4 1.3 1.0 2.8 0.1 0.0 0.0 2.2 0.1 3.9 0.0 0.3 6.5 0.5 0.7 0.6 1.2 6.5 0.7 0.0 3.6 0.9 11.2 1.4 0.0 4.4 2.5 0.4 3.9 0.0 0.2 3.7 0.0 1.3 6.1 26.6 0.3 1.9 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.5 0.4 0.8 0.4 0.0 0.0 0.0 0.0 1.4 6.4 2.6 3.6 1.0 0.8 0.2 0.3 7.4 0.4 IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 95.4;skin 1: 114.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 387.2;Basal prostatic cells: 253.9;Basal squamous epithelial cells: 217.9;Squamous epithelial cells: 251.9;Suprabasal keratinocytes: 552.4;Urothelial cells: 290.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 10.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 61.9;HaCaT: 210.7;HBEC3-KT: 80.5;hTCEpi: 170.1;hTERT-HME1: 82.2;RT4: 78.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA063121, HPA076162" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA063121: AB_2684942, HPA076162: AB_2686780" "unprognostic (2.59e-1)" "unprognostic (1.79e-3)" "unprognostic (1.74e-1)" "unprognostic (7.80e-2)" "unprognostic (1.33e-2)" "unprognostic (4.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.36e-1)" "unprognostic (7.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (2.03e-1)" "prognostic favorable (0.00e+0)" "unprognostic (2.70e-1)" "unprognostic (2.66e-2)" "unprognostic (2.14e-1)" "unprognostic (4.42e-2)" 1.6 11.4 1.6 3.2 1.5 2.8 35.9 10.9 1.8 21.6 5.2 27.1 26.9 5.9 49.3 95.4 21.7 10.8 29.7 1.7 1.4 17.0 33.3 8.8 0.9 1.9 2.9 1.9 19.7 26.4 6.5 20.4 1.9 32.4 31.5 2.4 39.0 26.4 0.5 114.0 25.0 2.0 2.1 2.1 24.8 2.9 2.3 20.3 17.1 2.7 23.0 40.5 46.8 1.2 61.9 0.0 0.0 0.0 0.4 0.0 20.9 0.1 0.5 0.1 0.3 13.6 20.7 0.0 0.1 0.1 0.0 210.7 0.0 80.5 0.0 0.0 1.3 0.1 0.2 0.0 0.2 0.0 0.2 0.1 170.1 0.1 82.2 0.0 3.7 0.0 0.1 0.2 0.0 8.3 0.0 0.3 1.2 17.0 0.2 0.0 0.0 0.3 7.7 78.8 18.7 6.1 1.4 34.1 1.9 3.8 24.1 0.3 0.0 0.0 0.1 0.0 0.3 0.8 15.8 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.6 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 1.6 1.5 10.9 1.8 1.7 1.4 1.9 2.9 1.9 2.1 2.3 1.2 1.9 16.0 10.4 0.3 1.0 387.2 253.9 154.0 217.9 0.1 47.2 33.3 26.0 32.9 70.4 35.0 0.0 94.2 1.3 95.5 27.4 36.7 1.1 120.2 9.5 6.0 59.9 0.4 0.0 19.2 25.4 4.5 53.0 121.7 2.5 0.0 1.1 35.9 8.3 0.0 0.1 74.9 38.7 1.0 30.1 0.7 0.6 2.3 35.6 1.9 1.0 6.5 0.0 0.0 0.0 49.2 43.8 0.0 2.5 153.9 49.5 11.9 82.1 0.6 0.0 0.4 7.4 8.2 3.7 251.9 552.4 161.6 2.5 0.7 44.5 290.3 ISCA2 "HBLD1, ISA2" ENSG00000165898 "Iron-sulfur cluster assembly 2" Q86U28 14 74493756-74497106 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030492 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA030492: AB_10603772" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "unprognostic (5.73e-2)" "unprognostic (5.62e-2)" "unprognostic (2.51e-1)" "unprognostic (5.89e-3)" "unprognostic (6.03e-3)" "unprognostic (7.98e-2)" "unprognostic (1.66e-1)" "unprognostic (2.59e-2)" "unprognostic (1.31e-2)" "unprognostic (2.21e-1)" "prognostic favorable (1.68e-7)" "unprognostic (3.98e-2)" "unprognostic (1.47e-1)" "prognostic favorable (8.98e-5)" "unprognostic (5.23e-2)" 15.1 33.9 20.3 9.7 20.6 15.5 16.9 22.4 23.9 13.7 27.4 16.9 14.2 11.0 46.4 15.4 19.5 7.6 34.3 19.5 21.2 30.6 22.0 12.9 17.0 21.2 21.1 18.1 18.1 12.9 23.4 12.8 21.3 18.5 17.5 19.1 17.8 12.1 38.3 13.3 16.0 8.4 21.1 20.0 18.1 20.6 22.6 18.5 26.0 29.2 17.4 13.7 13.4 21.5 43.4 30.7 28.4 18.1 25.5 37.2 35.9 19.7 26.3 30.2 36.3 36.3 39.3 21.8 25.3 16.6 38.2 30.7 27.8 25.9 40.7 30.7 20.2 13.7 13.1 39.6 38.3 17.7 30.2 31.2 29.0 18.2 20.6 28.0 30.8 44.4 18.2 25.5 32.7 51.0 42.9 34.5 21.0 60.2 28.3 29.8 31.9 21.8 42.6 34.1 19.1 19.6 20.8 24.4 31.8 30.5 60.2 20.9 16.9 17.1 39.5 25.3 17.7 43.3 60.3 40.2 28.0 20.6 25.4 130.8 109.1 159.0 91.8 108.0 93.5 172.3 127.6 111.6 111.0 165.4 148.5 122.1 87.5 101.5 106.6 218.1 157.4 161.3 20.3 20.6 22.4 23.9 19.5 21.2 21.2 21.1 21.3 21.1 22.6 21.5 25.2 19.2 20.4 7.2 36.2 15.4 27.2 74.9 13.6 22.1 36.2 38.2 113.3 22.8 42.7 33.1 12.5 70.8 28.8 45.5 146.8 62.0 41.0 38.3 17.6 27.2 29.3 73.2 4.4 55.0 70.1 28.8 24.5 18.1 12.6 31.8 28.9 42.4 81.5 28.6 5.5 36.3 63.1 33.2 18.3 19.3 33.5 30.4 8.8 2.8 49.0 69.8 41.2 3.0 7.2 59.5 50.8 18.0 25.0 40.2 51.4 133.5 78.6 31.6 13.1 15.1 25.1 107.2 63.7 25.4 13.2 25.4 30.7 43.1 42.3 27.6 ITFG1 "CDA08, LNKN-1, TIP" ENSG00000129636 "Integrin alpha FG-GAP repeat containing 1" Q8TB96 16 47154387-47464149 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 285.9;Oligodendrocytes: 263.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015590, HPA019728" Approved Approved "Intermediate filaments,Aggresome" "Intracellular and membrane" NA NA 28000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Intermediate filaments" Aggresome "HPA015590: AB_1846347, HPA019728: AB_1846348" "unprognostic (6.53e-3)" "unprognostic (9.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.27e-1)" "unprognostic (1.39e-3)" "unprognostic (3.70e-2)" "unprognostic (9.32e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "prognostic favorable (1.95e-8)" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (4.62e-3)" 25.3 42.2 18.5 16.4 23.8 12.5 25.2 17.1 22.0 28.8 26.0 35.1 30.5 27.8 31.2 19.1 26.3 28.8 44.7 23.7 22.9 47.8 45.4 27.4 13.5 13.6 14.0 28.0 27.3 56.0 15.7 40.7 15.9 29.4 33.1 33.3 21.8 28.9 23.8 12.9 26.7 29.1 16.6 19.3 28.3 36.7 18.5 17.2 43.2 24.6 16.7 24.4 13.8 19.5 22.2 24.8 44.0 31.1 84.1 65.0 54.1 50.7 72.9 45.6 24.3 14.2 51.8 25.9 70.4 63.5 30.9 31.9 21.6 33.0 44.9 11.8 17.0 14.0 22.0 33.2 39.4 32.7 59.6 48.3 55.6 23.3 30.1 96.3 44.4 24.2 40.3 33.5 58.3 21.1 20.2 16.3 14.5 27.4 24.5 31.0 43.4 66.5 60.2 15.9 21.9 30.8 46.0 53.6 24.0 43.7 23.7 29.9 43.0 48.9 23.7 26.3 20.7 47.6 66.7 48.4 48.9 20.6 39.2 17.9 33.9 33.4 16.0 33.0 15.2 16.6 19.0 17.7 25.8 17.2 20.7 17.4 21.2 23.8 33.1 17.5 26.1 29.2 18.5 23.8 17.1 22.0 23.7 22.9 13.6 14.0 15.9 16.6 18.5 19.5 38.9 51.3 28.1 165.9 37.2 38.4 43.4 81.3 27.9 50.8 32.6 23.2 56.8 50.1 62.2 82.8 47.9 100.6 32.3 79.3 9.8 60.5 129.0 33.0 28.7 37.8 61.9 27.8 250.7 52.4 86.4 48.5 41.8 35.0 8.2 54.5 39.3 68.7 50.9 40.4 285.9 43.2 73.2 53.8 30.0 32.0 35.1 41.9 28.4 146.1 45.4 39.4 38.1 214.6 263.5 45.3 37.0 61.3 60.1 35.3 65.2 49.6 54.5 47.4 78.9 30.1 49.8 93.7 98.3 25.5 30.3 114.0 29.9 66.0 38.1 37.4 ITGAL "CD11A, LFA-1" ENSG00000005844 "Integrin subunit alpha L" P20701 16 30472658-30523567 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction, Phagocytosis" "Integrin, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 118.6;monocytes: 36.8;NK-cells: 152.4;Plasma cells: 46.6;T-cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 121.7" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "HMC-1: 608.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025011 Enhanced NA NA 1600000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025011: " "unprognostic (1.10e-2)" "unprognostic (4.26e-3)" "unprognostic (3.72e-3)" "prognostic favorable (5.63e-5)" "unprognostic (2.88e-1)" "prognostic favorable (3.34e-4)" "unprognostic (1.63e-1)" "unprognostic (5.69e-3)" "prognostic favorable (5.57e-4)" "unprognostic (3.37e-2)" "unprognostic (4.98e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (2.89e-1)" "unprognostic (3.05e-2)" "unprognostic (1.39e-1)" "unprognostic (1.71e-2)" 4.2 1.4 0.3 36.7 0.5 36.8 2.3 0.3 1.0 2.4 0.5 5.5 6.0 2.3 1.0 2.5 3.0 7.0 1.4 0.3 0.4 2.6 10.6 22.0 62.4 1.6 1.1 1.3 1.0 0.5 1.2 3.0 1.4 2.4 8.6 0.0 5.3 1.4 0.9 1.4 19.7 3.6 0.7 64.9 8.6 1.0 1.6 55.2 3.5 0.9 46.4 6.9 2.3 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.1 0.0 1.1 608.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 134.3 0.0 0.0 43.3 3.5 0.0 0.0 0.0 0.1 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.4 26.0 0.0 0.0 0.0 0.0 0.0 36.6 12.5 0.0 0.1 3.8 0.0 5.3 24.4 17.0 56.6 48.0 27.7 4.8 21.4 42.7 22.3 1.7 9.4 29.7 14.3 24.2 121.7 6.0 15.6 43.6 0.3 0.5 0.3 1.0 0.3 0.4 1.6 1.1 1.4 0.7 1.6 2.1 1.2 6.4 10.5 0.7 19.1 0.8 0.3 0.0 0.0 0.4 1.2 1.0 1.9 0.0 1.9 1.8 0.0 0.2 118.6 0.3 0.0 0.1 0.5 4.1 0.6 2.3 0.0 4.8 3.6 0.0 0.6 1.4 1.1 0.9 5.1 0.1 5.3 4.9 19.3 0.0 2.8 0.2 0.0 30.0 3.4 0.7 0.0 31.5 1.8 15.9 36.8 0.1 152.4 0.5 1.6 0.0 0.0 0.0 46.6 0.1 0.9 0.3 6.7 0.9 0.0 1.2 0.7 0.2 0.2 0.1 0.3 0.7 84.9 0.1 0.0 0.2 ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847840 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 290.2;Inhibitory neurons: 183.1;Microglial cells: 84.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Immune cell enhanced" "Detected in many" "naive B-cell: 13.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.4;HEL: 41.1;HeLa: 74.9;HMC-1: 40.0;U-87 MG: 56.7" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 208.8" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" 10.6 12.0 1.8 11.8 12.0 7.2 17.3 49.9 20.1 11.5 15.6 19.5 4.5 36.5 10.0 10.6 27.1 14.1 10.1 5.9 0.0 13.9 3.9 13.7 11.2 0.0 0.5 25.3 6.7 45.3 16.0 8.0 0.0 21.7 6.3 3.9 16.1 27.9 3.0 5.0 11.5 24.5 0.0 9.2 11.1 4.5 0.0 10.3 31.7 5.3 10.5 27.9 11.8 6.1 0.4 4.1 1.0 3.0 27.7 1.9 11.8 0.9 0.5 1.3 0.8 1.3 1.2 14.5 0.6 1.9 6.5 0.1 2.2 2.6 2.1 76.4 3.2 41.1 74.9 3.5 27.4 17.7 40.0 9.2 4.0 5.8 1.1 7.6 7.2 8.4 7.9 13.9 3.7 1.8 7.2 3.0 2.1 0.5 9.7 4.2 1.0 1.1 1.7 5.5 0.7 19.5 5.4 4.3 4.3 0.9 2.6 20.6 13.5 1.8 4.3 3.7 2.3 17.7 12.0 9.6 56.7 17.0 2.7 5.8 2.0 1.5 2.3 0.9 1.7 6.7 1.6 1.6 2.2 13.4 2.7 1.6 1.8 1.8 0.9 4.7 1.4 1.1 1.8 12.0 49.9 20.1 5.9 0.0 0.0 0.5 0.0 0.0 0.0 6.1 30.1 0.0 31.4 24.8 49.7 3.8 6.1 6.3 11.4 4.0 40.0 29.7 8.0 2.8 11.2 9.2 0.0 0.5 17.8 0.3 3.9 2.4 5.4 9.1 11.9 31.2 3.5 8.4 290.2 5.1 0.5 21.5 20.4 12.7 26.5 22.6 36.0 2.0 4.7 1.7 183.1 1.3 2.0 12.9 17.4 7.9 30.1 23.9 7.2 84.3 14.2 4.3 6.2 25.1 12.7 1.5 1.2 52.6 8.8 5.4 0.3 3.9 13.1 1.5 39.5 8.8 28.2 1.5 2.9 4.9 3.1 1.0 25.7 22.0 0.8 3.3 IVD ACAD2 ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405485-40435947 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Theca cells: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA041391: AB_2677449, HPA044250: AB_2678875" "unprognostic (9.30e-2)" "unprognostic (3.31e-1)" "unprognostic (1.36e-2)" "unprognostic (4.24e-2)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "prognostic favorable (1.95e-5)" "unprognostic (1.50e-2)" "unprognostic (2.53e-1)" "unprognostic (2.84e-2)" "unprognostic (4.08e-2)" "unprognostic (2.31e-1)" "prognostic favorable (2.91e-9)" "unprognostic (1.40e-1)" "unprognostic (3.40e-2)" "unprognostic (1.14e-1)" "unprognostic (5.46e-3)" 25.8 80.5 35.1 14.5 40.8 15.9 45.3 35.6 40.8 29.4 39.5 31.6 24.3 26.4 29.0 16.0 35.0 21.5 61.7 34.0 41.5 59.1 145.4 24.3 19.6 40.2 38.8 43.3 27.4 39.2 58.3 15.3 37.5 42.1 27.2 13.0 31.8 36.8 55.7 8.6 26.8 23.8 37.9 27.9 46.7 25.0 44.5 16.8 119.2 55.4 19.5 31.1 20.8 45.3 20.9 11.9 22.9 38.9 35.9 32.9 1.0 27.6 32.7 39.4 24.0 36.5 16.0 0.8 57.7 43.4 32.6 20.8 45.9 46.6 30.1 36.4 34.0 52.1 36.2 38.9 64.6 22.0 48.5 45.3 18.5 23.5 55.3 46.3 38.8 60.4 2.5 2.4 42.1 27.1 27.3 38.9 17.8 1.3 33.0 41.2 32.6 27.9 45.2 51.6 37.3 21.5 38.2 83.4 18.7 21.5 69.0 117.6 27.6 29.9 20.2 23.6 24.9 54.5 38.5 1.0 30.9 22.8 28.4 17.0 24.8 36.7 33.3 36.1 31.0 27.5 18.5 26.6 58.8 27.6 18.5 26.7 2.3 39.4 73.1 89.2 26.9 24.3 35.1 40.8 35.6 40.8 34.0 41.5 40.2 38.8 37.5 37.9 44.5 45.3 13.1 28.9 54.5 27.4 19.0 2.3 21.0 17.3 13.1 26.0 27.5 22.2 88.0 45.8 29.9 44.1 14.6 20.3 34.0 17.9 95.9 19.7 5.4 21.4 31.0 18.6 19.7 21.3 15.3 14.9 7.3 20.2 29.6 19.9 34.7 46.5 21.4 135.0 28.1 16.8 16.6 24.4 14.2 18.3 6.2 7.4 20.5 18.6 5.4 21.5 28.8 26.0 26.8 25.1 21.4 14.8 9.4 24.8 10.0 16.6 22.0 97.3 29.3 19.9 19.7 25.0 18.2 16.1 3.7 17.4 0.6 9.9 18.0 105.7 35.4 11.9 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JCHAIN "IGCJ, IGJ, JCH" ENSG00000132465 "Joining chain of multimeric IgA and IgM" P01591 4 70655541-70681817 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 3028.0;intestine: 7979.6;stomach 1: 5916.2" "Cell type enriched" "Detected in many" 16 "Plasma cells: 101294.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 121 "memory B-cell: 4173.0;naive B-cell: 2555.1;plasmacytoid DC: 3578.1" "Group enriched" "Detected in all" 137 "B-cells: 4173.0;dendritic cells: 3578.1" "Cell line enhanced" "Detected in many" "Daudi: 3953.8;Karpas-707: 2117.6;RPMI-8226: 4469.2;U-266/70: 8794.0;U-266/84: 3519.2;U-698: 4949.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034436, HPA044132" Enhanced "Secreted to blood" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB034436: AB_2233368, HPA044132: AB_2678826" "prognostic favorable (1.81e-6)" "unprognostic (1.45e-3)" "unprognostic (7.44e-3)" "unprognostic (1.82e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.56e-7)" "unprognostic (2.37e-2)" "unprognostic (2.70e-2)" "unprognostic (6.30e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (3.43e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.96e-1)" 130.2 76.6 0.7 1089.0 0.8 76.3 3028.0 0.4 3.0 205.2 3.1 7979.6 6145.8 94.2 25.0 654.4 115.0 492.4 45.6 0.4 1.4 43.3 116.8 620.2 1033.5 1.9 1.0 183.5 78.3 2.1 2.0 2.4 0.8 90.2 6426.5 0.3 2420.5 258.4 4.2 13.2 4277.1 200.3 7.0 819.4 5916.2 40.0 0.8 155.3 19.4 0.8 1746.7 1059.4 11.6 2.8 8.9 0.0 0.0 0.0 0.0 0.0 15.5 8.2 1.5 0.1 0.1 0.0 0.0 3953.8 3.3 12.7 0.1 6.6 0.0 0.0 0.6 2.1 0.0 3.3 0.0 0.0 0.0 3.3 9.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 5.4 2117.6 0.1 0.0 6.1 14.9 4.9 0.0 0.0 4.8 2.6 4469.2 0.0 0.0 3.3 15.7 3.7 2.6 2.7 0.0 0.8 6.8 3.9 9.9 11.8 4.9 6.3 8794.0 3519.2 4949.0 2.1 5.2 1.2 25.1 7.5 2.6 4.0 1.5 19.1 4173.0 2.5 3.8 6.6 2555.1 2.1 2.1 28.3 4.5 2.5 3578.1 2.6 1310.4 0.7 0.8 0.4 3.0 0.4 1.4 1.9 1.0 0.8 7.0 0.8 2.8 3.0 22.4 101.3 0.0 6154.9 0.0 28.2 0.0 8.6 0.0 11.7 1.9 2.2 15.7 8.1 0.0 0.0 0.1 700.0 5.1 0.0 0.0 0.5 0.0 0.1 38.1 7.3 139.0 0.0 0.0 0.1 48.8 228.8 0.0 79.5 0.1 66.4 24.6 0.3 0.0 0.0 5.3 0.0 35.8 0.0 0.3 0.0 42.0 0.0 0.0 3.9 0.0 6.2 0.0 0.0 0.0 5.1 0.0 101294.9 32.7 0.0 5.4 3.6 0.0 0.0 0.6 88.4 1.4 0.3 24.3 0.0 0.3 1487.8 0.0 3.5 0.6 JMJD8 C16orf20 ENSG00000161999 "Jumonji domain containing 8" Q96S16 16 681670-684528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.32e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-2)" "unprognostic (2.87e-1)" "unprognostic (4.79e-2)" "unprognostic (1.46e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-2)" "unprognostic (1.63e-2)" "unprognostic (4.96e-3)" "unprognostic (5.53e-2)" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "unprognostic (7.04e-2)" 24.5 25.9 19.9 14.5 19.8 17.4 17.3 18.9 23.7 25.9 31.4 21.0 17.5 24.9 30.5 24.7 29.6 21.3 37.2 20.1 20.0 23.0 23.1 19.2 15.6 22.4 19.9 23.7 41.0 31.5 14.0 15.4 19.9 23.8 10.9 7.5 40.5 32.6 13.1 22.4 15.3 21.9 20.2 15.7 19.3 15.7 21.8 15.1 32.2 14.5 10.8 22.3 15.5 19.6 21.5 59.5 14.6 63.0 59.8 22.9 8.5 26.3 49.0 26.9 30.6 33.7 49.8 7.4 28.2 38.1 0.3 36.8 17.4 34.2 10.2 28.6 27.5 15.5 32.5 4.3 26.4 35.7 27.3 27.3 22.8 18.0 20.9 20.1 41.4 14.9 20.0 40.8 16.1 52.8 18.8 28.1 34.9 35.5 25.3 22.6 3.8 76.3 54.0 13.4 26.1 28.3 38.1 43.0 9.3 8.4 44.3 33.3 21.8 1.9 21.5 12.8 15.6 23.7 14.5 9.5 7.1 16.6 22.5 0.2 6.3 0.1 5.0 5.2 6.5 3.9 5.7 5.0 7.3 4.6 4.8 4.8 0.2 3.4 4.8 4.9 6.7 3.0 19.9 19.8 18.9 23.7 20.1 20.0 22.4 19.9 19.9 20.2 21.8 19.6 33.8 9.6 21.3 5.5 14.0 13.8 21.1 7.2 14.2 15.2 34.5 37.6 11.5 21.5 11.3 23.9 14.6 35.8 19.8 26.2 29.4 46.4 21.2 22.5 23.9 19.8 21.6 9.2 4.3 42.0 40.7 29.1 15.8 18.8 2.5 29.9 15.4 26.8 20.5 16.8 5.0 17.0 8.2 16.1 17.3 50.1 23.3 13.9 17.8 1.9 15.5 31.8 17.5 3.5 4.4 31.0 10.7 29.3 19.9 23.3 15.4 30.6 11.0 21.2 0.0 16.3 32.0 22.4 13.0 18.8 19.5 30.4 14.2 39.2 23.5 18.3 JPH2 JP-2 ENSG00000149596 "Junctophilin 2" Q9BR39 20 44106590-44187188 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.2;skeletal muscle: 120.4" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 64.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 15.3;EFO-21: 15.0;fHDF/TERT166: 19.1;HeLa: 12.6;SiHa: 12.9" "Low region specificity" "Detected in some" HPA052646 Approved NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA052646: AB_2681899" "unprognostic (1.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.61e-4)" "unprognostic (4.71e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.45e-3)" "unprognostic (6.87e-2)" "unprognostic (9.16e-2)" "unprognostic (2.57e-2)" "unprognostic (9.73e-2)" "unprognostic (4.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-2)" 6.0 1.9 0.5 4.5 0.6 0.1 5.7 0.4 0.7 15.1 0.7 63.3 2.1 51.6 2.9 11.9 30.0 3.5 85.2 0.4 0.5 1.4 0.3 5.2 0.2 1.1 1.1 3.9 0.3 0.1 1.2 3.8 0.8 23.8 4.5 0.2 5.8 22.1 120.4 3.8 11.8 27.5 0.9 1.3 16.0 0.8 0.6 0.1 1.5 48.3 0.1 40.5 10.6 0.7 7.5 0.8 0.4 0.0 0.3 0.4 1.5 2.2 4.1 5.4 2.3 15.3 5.9 0.0 15.0 19.1 6.1 10.5 0.0 0.5 2.1 0.0 0.0 0.0 12.6 0.1 0.1 0.3 0.0 0.7 1.1 2.7 3.7 3.3 0.0 0.0 0.0 0.0 7.3 4.3 0.0 0.2 0.3 0.0 0.9 1.7 3.4 0.0 0.4 0.1 0.0 0.1 12.9 3.1 0.1 8.6 10.8 0.1 0.3 2.4 2.7 0.5 4.7 0.1 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.4 0.7 0.4 0.5 1.1 1.1 0.8 0.9 0.6 0.7 0.2 0.0 0.0 0.3 0.0 6.6 0.5 0.9 0.0 0.0 0.4 5.1 64.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.8 0.0 0.5 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 0.0 6.6 15.9 12.8 0.0 1.5 0.0 2.0 0.5 0.1 0.0 0.2 0.1 JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.3;Ductal cells: 90.1;Endometrial ciliated cells: 107.3;Extravillous trophoblasts: 205.9;Glandular and luminal cells: 77.5;Pancreatic endocrine cells: 78.9;Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Approved Approved "Plasma membrane,Cytosol" NA NA 76000 "Cluster 22: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041888: AB_10793937, HPA041908: AB_10794160" "unprognostic (1.49e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-3)" "prognostic favorable (7.85e-4)" "unprognostic (3.60e-1)" "unprognostic (2.37e-2)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.22e-3)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (2.78e-2)" 21.2 17.0 12.7 18.6 21.1 11.3 36.4 33.2 19.8 39.5 14.1 32.7 21.9 21.1 17.9 47.7 63.4 13.6 20.3 12.0 16.3 48.8 41.1 20.0 19.9 58.0 27.8 19.8 29.6 20.9 15.1 48.1 46.9 47.9 30.5 4.6 26.6 18.2 17.5 31.3 24.2 19.5 28.4 12.8 28.2 18.1 25.6 35.5 27.7 14.0 31.3 31.2 25.9 51.7 148.1 147.5 168.4 93.9 23.9 39.3 151.9 143.6 44.8 117.7 99.8 194.5 188.3 94.6 107.8 71.1 116.4 141.9 223.5 194.2 135.7 77.2 135.2 78.4 80.2 111.4 36.7 93.5 44.8 28.1 121.6 116.4 149.6 64.9 75.7 85.4 187.5 37.0 68.6 169.5 117.1 46.6 185.3 164.4 112.0 212.7 159.3 136.2 186.2 82.5 156.1 85.6 214.9 205.3 66.5 161.1 250.3 59.6 87.9 113.9 201.1 54.8 141.1 31.5 136.3 198.8 35.8 71.5 170.5 2.1 3.7 4.1 5.2 3.3 7.2 4.8 5.8 4.2 2.8 7.6 6.3 5.4 0.3 6.8 1.7 6.6 5.8 4.4 12.7 21.1 33.2 19.8 12.0 16.3 58.0 27.8 46.9 28.4 25.6 51.7 11.9 25.6 10.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 33.3 23.4 0.0 0.0 12.4 9.2 0.0 99.3 4.5 0.0 43.0 90.1 0.0 107.3 19.2 8.5 0.0 0.0 0.0 25.6 205.9 7.4 0.0 77.5 2.5 23.4 0.0 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 28.4 0.0 0.0 0.0 0.0 78.9 0.0 0.0 1.2 0.0 0.0 26.0 27.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 168.7 3.6 18.9 0.0 0.0 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Vesicles, Cytosol" "HPA016953: AB_1851277, HPA074328: " "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 31.6 30.0 38.7 23.8 41.0 52.9 32.1 41.7 48.8 39.5 38.6 43.6 21.6 45.1 33.7 34.9 44.9 20.5 32.4 37.9 38.9 32.9 26.3 29.5 28.0 40.0 39.5 39.2 32.7 45.6 33.7 29.9 41.2 33.1 27.0 31.0 29.6 36.3 42.8 47.6 32.2 35.2 40.0 34.3 35.9 45.2 39.9 39.3 38.2 34.6 30.2 39.5 34.8 43.8 37.2 44.1 40.1 29.6 31.3 32.7 41.1 26.7 43.6 44.0 38.0 32.6 42.2 34.3 36.2 47.4 47.5 30.8 50.8 45.1 26.4 44.4 32.5 50.6 36.3 38.9 44.6 55.7 56.4 35.2 49.7 28.9 59.0 33.7 28.1 39.1 52.5 51.1 42.0 68.2 45.7 62.3 33.9 26.8 28.4 38.2 26.5 63.3 40.6 56.2 37.1 38.9 25.4 46.5 51.2 20.8 45.9 34.2 36.3 33.9 30.4 27.6 28.0 38.7 43.7 50.4 29.7 27.0 29.3 42.7 33.6 58.8 33.4 32.0 29.6 28.2 28.8 34.2 34.1 30.4 36.5 29.8 34.8 35.8 34.6 20.9 31.0 36.4 38.7 41.0 41.7 48.8 37.9 38.9 40.0 39.5 41.2 40.0 39.9 43.8 17.6 12.8 17.5 10.7 26.0 21.2 44.2 60.2 17.6 44.9 17.3 15.0 1.0 25.8 33.8 29.5 31.3 51.3 25.6 27.1 35.2 42.2 11.1 20.2 14.2 18.7 30.4 12.4 7.5 51.5 42.6 21.1 20.4 19.8 33.7 27.0 18.2 10.9 36.3 38.7 8.7 25.1 42.7 17.6 15.2 11.1 28.0 20.4 42.7 3.7 38.8 40.3 33.0 7.1 13.8 39.4 30.6 38.7 10.4 24.2 23.3 32.6 30.0 44.8 46.0 27.6 27.0 61.1 27.8 14.6 21.3 102.5 21.6 29.2 26.2 31.0 KAT7 "HBO1, HBOA, MYST2, ZC2HC7" ENSG00000136504 "Lysine acetyltransferase 7" O95251 17 49788648-49835026 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044470, HPA071116" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA044470: AB_10965785, HPA071116: " "unprognostic (1.30e-1)" "unprognostic (3.15e-2)" "unprognostic (6.20e-3)" "unprognostic (2.20e-2)" "unprognostic (7.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (1.36e-1)" "unprognostic (6.26e-2)" "unprognostic (1.44e-2)" "unprognostic (2.52e-1)" "unprognostic (1.33e-3)" "unprognostic (2.75e-1)" "unprognostic (5.03e-2)" "unprognostic (6.23e-2)" "unprognostic (7.68e-2)" 17.6 14.2 16.1 8.1 16.9 40.9 16.6 24.2 21.5 20.1 15.1 20.9 7.2 22.6 12.2 20.4 20.3 6.6 22.8 16.5 14.8 17.7 11.7 14.5 10.4 13.6 12.3 20.9 12.4 23.5 17.1 10.0 15.5 17.5 10.0 19.2 17.8 14.0 37.7 25.5 16.0 12.4 10.3 15.9 16.0 38.6 14.9 17.4 21.1 20.1 13.5 22.5 19.0 18.7 17.1 22.6 22.5 17.3 10.1 14.3 27.2 11.2 16.5 24.7 18.7 35.9 11.5 17.8 21.8 13.7 24.7 16.7 23.0 12.8 32.5 18.6 20.3 20.7 14.8 17.8 15.0 21.6 17.2 13.3 16.6 21.1 25.3 14.4 22.7 16.0 23.6 18.9 27.4 28.8 26.4 23.2 79.0 38.4 20.2 20.6 34.7 18.2 12.8 17.6 25.7 15.7 7.6 9.2 14.9 40.5 38.6 22.9 8.8 24.5 13.3 16.0 19.4 21.4 32.7 23.3 17.3 13.6 23.3 17.1 6.8 9.5 8.3 5.4 10.6 5.8 7.8 8.5 7.0 6.1 9.3 8.5 10.1 11.7 7.1 4.3 8.5 7.9 16.1 16.9 24.2 21.5 16.5 14.8 13.6 12.3 15.5 10.3 14.9 18.7 16.0 25.6 21.3 9.4 23.6 16.8 11.7 10.1 25.0 32.6 18.5 16.6 28.5 20.0 15.6 27.6 31.3 22.7 27.6 11.7 9.8 11.9 23.1 22.4 21.0 18.7 25.1 25.4 14.8 7.5 14.5 15.3 15.3 29.9 24.1 18.2 15.4 10.4 13.3 45.4 16.7 13.4 12.2 22.6 13.2 16.5 16.8 15.9 14.2 10.3 19.1 16.5 25.7 13.0 18.3 10.0 8.9 18.4 18.6 15.4 12.8 10.2 18.6 25.1 39.5 21.2 24.2 73.7 31.6 17.9 20.0 33.8 28.4 15.2 12.1 10.2 KBTBD7 DKFZP434E2318 ENSG00000120696 "Kelch repeat and BTB domain containing 7" Q8WVZ9 13 41189834-41194569 "Predicted intracellular proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 53.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA043709, HPA046861, HPA048914" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "HPA043709: AB_10961260, HPA046861: AB_2679843, HPA048914: AB_2680554" "unprognostic (8.68e-2)" "unprognostic (6.36e-2)" "unprognostic (3.67e-1)" "unprognostic (3.28e-2)" "unprognostic (5.46e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic favorable (5.29e-4)" "unprognostic (4.36e-2)" "unprognostic (7.59e-2)" "prognostic favorable (6.62e-4)" "unprognostic (4.98e-1)" "unprognostic (1.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.68e-2)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" 2.9 4.1 4.5 2.9 4.9 4.4 5.4 6.5 5.8 4.5 4.8 3.1 3.9 3.4 5.2 2.4 5.0 2.2 4.6 4.4 4.4 5.4 6.9 3.1 4.3 4.3 4.5 5.8 4.2 6.2 3.1 4.4 4.7 5.9 2.7 6.0 5.9 5.0 4.2 3.5 3.1 2.7 4.8 4.5 4.9 3.5 4.4 4.7 6.3 4.0 4.6 2.8 1.5 6.1 2.2 4.5 9.0 10.5 9.5 4.1 3.3 2.2 3.1 2.9 2.0 5.9 4.2 3.9 3.3 2.8 3.8 7.3 6.9 4.7 2.9 5.4 8.8 10.5 6.0 5.3 4.4 1.8 8.3 2.3 8.2 1.0 2.7 5.4 3.2 7.1 5.1 0.4 5.6 6.5 9.5 4.1 8.9 9.4 2.3 10.4 5.7 2.0 6.3 5.0 5.2 7.1 3.3 9.9 3.1 7.9 6.0 9.6 3.2 1.7 2.2 1.6 1.9 2.6 3.3 0.0 4.1 4.7 4.1 2.1 5.0 11.5 2.9 5.1 3.4 2.3 3.4 3.4 3.6 2.1 5.0 4.5 13.7 3.2 3.9 1.8 2.6 2.9 4.5 4.9 6.5 5.8 4.4 4.4 4.3 4.5 4.7 4.8 4.4 6.1 10.4 9.6 6.7 4.2 8.3 4.1 14.3 10.3 13.1 27.8 17.2 15.1 9.2 17.2 9.2 12.9 14.6 16.8 7.1 17.1 19.6 6.6 53.2 5.6 9.6 9.7 12.7 16.0 5.4 5.8 14.7 16.6 16.3 8.6 8.9 10.7 15.7 27.6 8.5 5.0 7.2 12.5 16.2 14.2 3.5 5.1 15.8 7.5 5.4 4.7 10.0 17.2 13.4 9.0 9.7 3.7 13.7 21.8 6.1 6.9 12.4 17.4 6.2 19.2 19.7 15.6 12.5 17.7 15.0 10.6 6.8 9.9 6.7 12.2 11.3 11.5 KCNMA1 "KCa1.1, mSLO1, SLO" ENSG00000156113 "Potassium calcium-activated channel subfamily M alpha 1" Q12791 10 76869601-77638369 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 138.7" "Cell type enhanced" "Detected in many" "Astrocytes: 471.1;Bipolar cells: 409.8;Excitatory neurons: 1023.7;Inhibitory neurons: 635.9;Oligodendrocyte precursor cells: 708.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 2.4" "Cell line enhanced" "Detected in many" "BJ: 100.8;hTERT-HME1: 115.3;PC-3: 159.6;U-138 MG: 112.6;U-87 MG: 109.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054648 Approved NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA054648: AB_2682556" "unprognostic (1.25e-1)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" "unprognostic (5.29e-2)" "unprognostic (9.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.77e-1)" "unprognostic (2.81e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" "unprognostic (4.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.26e-2)" "unprognostic (1.42e-2)" "unprognostic (5.19e-2)" "unprognostic (1.42e-2)" "unprognostic (3.99e-3)" 10.9 12.6 36.2 8.9 38.0 1.0 15.8 1.0 45.0 54.4 4.2 118.2 7.3 138.7 31.4 33.7 47.8 22.4 3.7 36.4 10.1 11.4 19.2 9.6 7.8 4.8 15.2 13.9 8.0 0.2 26.9 4.8 5.7 48.3 21.1 40.2 42.8 76.1 96.6 5.0 23.3 92.8 1.0 24.1 33.6 5.8 15.6 2.1 3.0 18.7 3.5 44.3 24.6 28.4 0.3 30.3 0.1 0.3 4.6 24.8 0.3 100.8 89.2 23.9 11.8 6.7 0.6 0.0 0.7 75.9 56.8 0.2 0.0 59.0 14.6 60.9 0.6 0.0 0.0 0.0 45.0 0.0 0.4 17.4 10.7 38.3 115.3 84.0 9.8 0.5 0.0 0.0 42.6 1.2 1.9 0.2 1.8 0.2 159.6 0.1 3.6 0.1 15.3 0.2 9.1 1.1 0.0 2.5 0.1 11.9 12.2 0.1 65.4 112.6 12.7 20.6 90.0 0.0 0.2 0.0 109.8 0.1 45.1 0.0 0.1 0.0 0.0 2.4 0.0 0.7 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.1 36.2 38.0 1.0 45.0 36.4 10.1 4.8 15.2 5.7 1.0 15.6 28.4 0.9 0.0 4.3 471.1 2.8 2.0 71.7 5.7 17.6 409.8 30.4 43.9 3.5 5.7 4.8 1.8 60.5 0.3 0.5 2.8 29.4 3.3 74.4 20.9 17.9 3.4 4.9 0.0 1023.7 10.7 0.2 16.2 0.5 29.7 0.0 1.9 2.5 27.3 10.8 6.7 635.9 59.6 46.8 106.0 3.9 63.1 3.7 36.7 48.0 133.0 4.0 52.3 0.0 708.2 33.9 8.7 1.4 1.2 8.7 64.0 1.4 0.9 0.1 17.2 6.6 20.6 19.2 3.4 2.5 7.7 0.3 0.3 0.7 177.2 1.7 2.4 KCNMB1 hslo-beta ENSG00000145936 "Potassium calcium-activated channel subfamily M regulatory beta subunit 1" Q16558 5 170374671-170389634 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 59.2;intestine: 75.1;smooth muscle: 53.1" "Cell type enriched" "Detected in many" 6 "Peritubular cells: 354.3" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;monocytes: 5.9" "Cell line enhanced" "Detected in some" "REH: 8.8;SK-BR-3: 2.1;U-937: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "unprognostic (2.06e-2)" "unprognostic (2.70e-4)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.37e-2)" "unprognostic (8.88e-2)" "unprognostic (1.61e-2)" "unprognostic (3.46e-1)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (5.37e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.13e-6)" "unprognostic (1.08e-1)" "unprognostic (2.49e-1)" "unprognostic (4.31e-2)" "unprognostic (1.04e-2)" 5.7 1.8 2.7 10.5 2.3 1.7 6.9 2.5 2.7 16.8 1.4 75.1 4.3 59.2 6.2 16.6 20.6 7.3 4.2 2.1 2.4 1.4 0.7 4.0 1.7 5.9 4.0 4.0 0.7 0.3 0.5 1.1 6.2 24.5 8.9 1.1 6.8 50.6 1.0 2.9 14.3 53.1 3.4 2.3 21.5 2.7 4.2 1.0 1.4 1.1 1.3 32.6 11.2 3.9 0.1 0.1 1.5 0.3 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.3 0.1 1.0 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.1 1.2 0.6 0.2 0.0 0.4 0.2 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.7 0.1 0.7 0.0 0.8 0.3 0.0 0.1 8.8 0.0 0.2 0.0 0.2 0.4 0.2 0.1 2.1 0.0 0.7 0.1 1.0 0.5 0.2 0.3 0.3 0.0 0.4 0.2 0.1 0.1 3.8 0.1 1.3 3.3 0.3 0.1 5.9 0.1 0.2 0.2 0.1 5.7 0.3 0.1 0.1 0.9 0.4 5.1 2.0 0.2 1.0 2.7 2.3 2.5 2.7 2.1 2.4 5.9 4.0 6.2 3.4 4.2 3.9 1.3 0.0 6.3 0.3 1.2 2.0 1.2 0.4 0.0 1.6 2.5 55.1 3.7 4.3 4.5 1.8 6.2 0.5 1.7 0.1 0.0 0.1 0.6 0.6 14.4 3.6 0.0 1.3 0.1 0.4 0.6 9.8 0.0 0.6 19.7 0.4 1.8 0.4 7.4 1.7 0.3 0.2 0.0 18.9 10.9 4.5 38.5 15.6 3.6 4.7 27.8 0.6 2.1 0.0 0.1 0.0 0.0 354.3 0.3 1.3 0.0 0.1 4.5 2.3 46.0 2.2 43.6 0.7 1.2 0.1 1.7 0.5 1.7 1.4 0.0 0.7 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 13.7;Breast myoepithelial cells: 12.8;Exocrine glandular cells: 17.1;Gastric mucus-secreting cells: 14.3;Intestinal goblet cells: 20.8;Prostatic glandular cells: 14.3;Proximal tubular cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 26.1;Hep G2: 29.0;RPTEC TERT1: 45.9;U-2 OS: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Vesicles, Cytosol" "HPA041118: AB_10963117, HPA042181: AB_10968059" "unprognostic (7.37e-3)" "unprognostic (4.27e-2)" "unprognostic (7.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.96e-5)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.19e-1)" "prognostic favorable (6.92e-5)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.63e-1)" 3.4 23.1 2.0 1.6 2.0 0.1 20.4 5.1 2.9 10.4 3.2 8.1 4.9 3.4 14.3 1.5 11.7 6.7 0.6 2.1 2.1 11.5 10.3 8.2 0.3 1.9 2.3 0.8 27.2 8.3 2.5 1.3 2.2 7.0 11.9 1.6 28.7 19.1 0.2 1.9 5.2 2.1 1.6 0.6 20.8 0.6 2.5 1.3 15.9 0.6 0.5 2.3 1.4 1.7 0.0 3.5 0.6 0.5 1.3 0.8 3.5 1.8 1.6 3.4 8.4 13.5 8.8 0.1 9.3 1.1 0.4 1.0 0.6 26.1 8.9 0.5 13.2 0.0 3.0 29.0 4.9 0.2 0.1 4.0 0.7 13.9 11.0 2.5 1.0 0.2 0.3 0.1 1.4 0.2 0.3 0.8 6.5 0.5 0.5 0.4 0.0 0.0 45.9 3.5 2.3 0.2 0.0 0.2 4.5 0.8 1.4 1.1 0.8 0.2 20.2 0.7 0.4 0.3 0.2 0.2 0.2 0.2 3.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.0 2.0 2.0 5.1 2.9 2.1 2.1 1.9 2.3 2.2 1.6 2.5 1.7 0.6 3.2 10.8 0.0 0.2 0.4 12.2 2.0 2.8 0.4 13.7 12.8 0.0 1.5 4.1 5.5 0.0 0.6 0.3 5.2 3.9 2.6 0.3 2.7 2.0 0.9 4.8 0.0 0.0 17.1 1.3 1.1 14.3 3.7 1.3 0.5 0.0 4.8 0.2 0.0 0.0 20.8 0.0 0.0 0.0 0.0 3.4 0.4 1.8 0.0 0.1 2.1 0.0 0.0 0.0 10.5 6.6 5.3 0.0 14.3 2.2 15.1 0.1 0.0 0.0 0.0 1.8 0.2 0.3 0.7 0.1 0.7 0.3 0.7 8.5 7.4 KCTD2 KIAA0176 ENSG00000180901 "Potassium channel tetramerization domain containing 2" Q14681 17 75032575-75065889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 24.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 37.8;Horizontal cells: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 8.7;K-562: 8.8;MOLT-4: 8.6;U-266/70: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (1.62e-1)" "unprognostic (1.83e-1)" "unprognostic (2.66e-1)" "unprognostic (1.00e-3)" "unprognostic (1.73e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (1.83e-4)" "unprognostic (5.43e-2)" "unprognostic (3.34e-1)" "unprognostic (6.58e-2)" "prognostic favorable (1.25e-5)" "unprognostic (7.19e-2)" "unprognostic (9.57e-3)" "unprognostic (2.13e-1)" "unprognostic (6.10e-2)" "unprognostic (1.16e-2)" "unprognostic (1.60e-1)" 3.0 1.3 8.1 0.0 10.7 0.6 1.1 24.8 13.9 1.4 2.7 1.3 0.1 1.5 0.0 1.1 1.7 0.0 1.0 8.7 6.0 1.6 0.4 0.8 0.1 5.0 6.9 1.8 0.5 0.0 1.1 0.5 7.5 1.0 0.0 0.3 1.2 0.3 3.6 1.9 0.9 0.0 12.4 0.8 1.0 2.2 11.8 0.0 1.1 0.0 0.0 2.0 1.1 11.4 5.3 0.0 0.1 1.2 0.4 1.2 2.6 7.6 0.7 0.0 0.7 1.0 0.0 7.2 8.0 1.4 0.2 3.4 0.0 0.0 0.0 6.4 8.7 0.8 0.7 0.0 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 8.8 0.5 0.0 0.0 8.6 1.4 2.1 0.1 6.8 8.0 0.3 1.8 0.0 0.2 1.1 4.4 1.7 0.1 3.3 0.1 0.9 0.5 1.7 0.1 6.3 0.5 6.0 11.4 4.6 2.4 1.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 8.1 10.7 24.8 13.9 8.7 6.0 5.0 6.9 7.5 12.4 11.8 11.4 8.2 3.2 11.6 8.8 3.2 2.8 2.5 3.8 6.2 37.8 9.6 10.4 15.5 4.3 3.4 7.3 0.0 6.2 5.8 6.7 7.9 4.0 4.6 4.4 8.5 8.0 3.0 0.8 11.8 5.3 4.4 7.6 4.1 5.8 1.3 11.8 15.7 6.6 5.0 35.3 14.0 5.2 6.1 11.6 2.1 9.8 10.8 5.2 3.6 5.6 6.9 17.6 7.2 9.5 21.7 5.3 3.4 23.3 5.3 7.2 4.4 7.4 5.2 9.8 0.0 7.3 6.3 5.2 17.0 4.8 5.1 4.4 4.6 14.5 6.1 4.1 KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 856.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: AB_10615208" "unprognostic (3.10e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.49e-4)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.35e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.55e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.06e-1)" "unprognostic (1.68e-2)" 109.3 124.4 58.0 61.7 56.5 45.8 106.6 54.5 59.7 132.5 78.1 120.3 132.5 110.0 117.3 107.3 112.2 100.9 96.6 56.1 62.5 119.5 127.2 101.4 53.3 61.1 59.1 165.8 138.9 191.7 116.2 128.7 59.0 102.5 128.5 39.0 137.7 105.0 76.8 103.8 114.5 100.6 56.2 79.5 120.1 93.7 62.9 51.6 121.8 58.4 73.2 102.5 102.4 58.0 216.2 305.3 173.1 184.7 379.7 440.6 126.5 207.4 363.9 247.0 281.0 202.3 238.7 89.1 132.6 456.4 154.4 187.6 211.1 222.2 234.0 72.7 224.5 74.4 99.4 382.2 329.6 84.1 133.4 419.6 268.0 168.5 178.5 387.4 233.0 75.3 131.7 160.9 333.1 173.6 79.4 856.7 126.3 426.8 122.5 112.1 103.4 141.0 316.2 176.3 172.9 134.5 182.1 160.6 113.1 196.7 126.6 102.1 182.6 173.4 142.6 145.3 179.3 451.1 382.0 60.2 110.1 112.4 181.1 10.8 41.0 12.6 18.1 34.7 20.8 17.0 17.6 19.7 30.6 14.3 14.3 16.1 9.9 20.2 30.2 45.4 20.4 18.2 58.0 56.5 54.5 59.7 56.1 62.5 61.1 59.1 59.0 56.2 62.9 58.0 150.8 35.3 54.2 8.5 82.2 75.3 130.6 147.1 124.7 39.4 141.0 154.4 28.8 98.7 110.9 93.8 6.2 231.7 59.5 153.0 56.7 224.1 6.2 72.0 188.8 111.4 145.0 56.8 8.7 169.0 605.5 161.0 120.3 166.3 62.7 149.2 102.8 79.6 180.0 40.4 12.7 379.6 93.6 107.6 73.5 14.2 163.5 103.1 92.5 8.4 102.3 89.8 35.0 10.6 10.6 190.3 199.8 132.0 365.9 161.2 213.8 149.6 49.2 28.1 85.5 87.9 131.6 41.8 69.1 127.7 70.2 387.7 55.4 191.3 202.9 157.6 KDM1B "AOF1, bA204B7.3, C6orf193, dJ298J15.2, FLJ33898, FLJ34109, FLJ43328, LSD2" ENSG00000165097 "Lysine demethylase 1B" Q8NB78 6 18155329-18223854 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 7.2;monocytes: 8.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031269, HPA055597" Uncertain Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA031269: AB_10601587, HPA055597: " "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.57e-2)" "unprognostic (7.25e-2)" "unprognostic (1.08e-1)" "unprognostic (5.57e-3)" "unprognostic (1.32e-2)" "unprognostic (8.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.16e-1)" "unprognostic (3.17e-2)" "unprognostic (6.68e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (7.36e-2)" "unprognostic (3.53e-1)" 5.9 7.6 5.6 11.4 7.6 27.2 6.3 5.3 7.8 7.6 7.6 14.1 8.0 5.7 3.7 9.1 13.4 6.0 6.8 6.6 5.9 7.8 7.4 8.8 10.4 6.9 6.7 6.7 5.9 3.2 5.8 4.6 6.1 5.2 12.2 12.0 5.7 4.7 17.3 11.2 8.9 6.9 6.2 10.5 5.6 15.7 5.6 10.8 27.2 9.1 9.4 7.7 8.1 9.4 15.1 9.7 11.2 23.0 13.8 20.5 24.5 11.7 12.6 7.5 10.2 16.3 7.4 34.1 31.6 19.2 22.8 15.5 17.8 20.8 16.0 31.6 14.6 17.2 8.6 15.0 6.7 25.5 17.5 10.3 23.4 21.5 17.7 12.1 7.7 15.9 38.3 5.2 12.7 12.6 14.1 10.5 3.8 31.6 12.8 26.8 20.3 24.4 10.7 19.8 34.2 10.6 9.7 23.5 22.9 11.7 22.3 20.3 6.5 16.9 9.5 11.9 15.5 5.2 15.9 20.0 6.4 18.9 37.8 1.2 4.6 7.2 0.5 8.6 0.3 1.2 0.5 0.5 3.7 1.3 0.5 0.2 4.9 0.3 6.9 1.6 0.7 1.3 5.6 7.6 5.3 7.8 6.6 5.9 6.9 6.7 6.1 6.2 5.6 9.4 4.9 0.0 8.2 14.7 8.7 12.7 5.7 3.8 7.4 5.0 7.6 6.6 10.4 11.5 10.4 1.8 10.4 2.7 3.0 23.0 1.9 6.6 0.7 36.2 10.0 4.2 6.7 3.8 19.0 4.3 5.1 5.8 8.2 15.5 2.5 3.3 4.2 7.7 7.5 5.0 10.8 9.6 10.2 36.7 11.7 0.7 3.7 20.6 7.2 22.5 27.7 6.6 8.2 16.1 23.8 7.2 21.2 6.8 3.7 5.4 6.2 11.2 21.0 15.5 0.0 6.9 6.2 0.7 18.2 9.7 15.9 1.4 5.6 3.1 10.6 6.6 KIAA0319L "AAVR, KIAA1837" ENSG00000142687 "KIAA0319 like" Q8IZA0 1 35433492-35557950 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 47.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072692 Supported Supported "Nucleoli,Golgi apparatus" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoli "HPA072692: AB_2686549" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (4.23e-3)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (5.92e-5)" "unprognostic (3.41e-3)" "unprognostic (1.19e-1)" "unprognostic (1.44e-1)" "unprognostic (2.05e-2)" "unprognostic (3.79e-1)" "prognostic favorable (1.27e-4)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (5.44e-2)" "unprognostic (1.84e-1)" 14.3 26.6 28.3 13.0 28.0 15.9 27.8 23.4 28.0 25.6 28.9 25.6 26.3 14.4 26.2 18.3 35.1 21.3 44.5 28.0 27.6 38.2 34.2 30.9 17.7 26.9 29.2 14.9 42.1 45.6 26.9 30.6 25.5 34.9 30.0 34.1 33.5 18.5 37.7 20.1 24.8 14.4 24.8 20.1 34.4 17.1 32.4 17.8 41.4 40.1 16.8 15.8 15.1 24.9 13.5 19.6 39.8 31.5 52.7 36.9 37.8 17.9 37.8 25.5 37.5 21.2 52.9 15.0 48.0 19.6 38.1 26.1 29.7 28.8 28.9 23.8 21.7 20.3 23.4 23.6 41.3 16.9 26.8 52.3 36.2 29.5 38.0 84.3 42.2 18.1 27.2 21.0 35.2 13.6 10.1 14.3 45.3 37.4 11.7 11.3 33.8 18.7 41.8 32.4 8.7 24.6 25.8 30.6 53.3 86.9 32.3 23.1 43.6 17.4 18.7 14.9 28.0 31.1 26.7 9.8 44.3 21.8 17.7 8.8 19.4 9.4 5.0 6.1 4.8 3.4 4.1 4.7 5.6 4.1 5.5 4.0 47.2 9.8 4.0 3.7 4.0 8.7 28.3 28.0 23.4 28.0 28.0 27.6 26.9 29.2 25.5 24.8 32.4 24.9 24.2 73.7 74.1 85.2 18.3 7.9 14.4 16.5 15.4 74.8 33.9 26.0 55.0 47.1 42.4 35.0 108.4 33.3 16.6 35.4 3.9 19.2 9.6 21.0 17.7 24.6 21.6 14.7 93.2 32.5 22.5 19.4 28.5 30.8 21.5 42.7 28.9 47.4 19.1 63.9 95.2 59.5 16.2 31.4 7.6 7.5 17.4 19.2 14.2 62.8 31.4 30.5 29.9 115.1 99.3 30.3 27.6 17.3 17.2 26.0 36.8 17.5 45.4 61.9 6.6 24.5 15.7 22.5 21.2 17.8 9.2 31.2 21.9 30.1 31.2 14.8 KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.7;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 9.0;Extravillous trophoblasts: 3.8;Granulosa cells: 5.9;Oligodendrocyte precursor cells: 7.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" HPA024205 Enhanced Supported "Nucleoplasm,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Microtubule ends" "Nuclear bodies, Cytosol" "HPA024205: AB_1852472" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (4.61e-2)" "unprognostic (1.13e-2)" "unprognostic (4.17e-1)" "unprognostic (7.27e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (3.34e-3)" "prognostic unfavorable (6.90e-4)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (8.18e-2)" "unprognostic (0.00e+0)" "unprognostic (4.69e-3)" "unprognostic (1.93e-1)" "unprognostic (3.08e-1)" "unprognostic (1.68e-2)" 0.4 0.4 0.3 3.8 0.4 12.7 0.2 0.7 0.3 0.9 0.3 2.0 2.7 0.4 0.0 5.1 0.2 0.4 0.3 0.3 0.4 0.2 0.4 0.8 5.7 0.5 1.1 0.1 0.1 0.0 0.1 1.9 0.6 0.2 1.7 0.1 0.7 0.0 0.4 3.0 2.5 1.1 0.3 2.9 1.5 2.9 0.6 14.4 0.2 0.0 4.7 0.6 1.6 0.5 31.5 41.7 35.3 32.8 0.8 3.0 28.1 25.8 10.3 34.6 26.9 34.0 27.4 28.3 10.9 10.8 21.5 34.0 25.1 11.3 17.9 56.6 36.4 35.4 51.7 22.1 0.0 30.0 30.2 0.7 0.6 29.7 12.2 4.7 17.9 29.2 28.1 48.0 18.2 25.9 60.0 31.1 25.4 30.4 28.9 43.5 51.8 19.2 5.8 16.7 26.2 24.7 18.0 16.1 9.8 17.0 30.2 21.6 11.2 49.9 48.0 28.8 56.8 15.1 15.7 34.4 16.3 22.9 33.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.4 0.7 0.3 0.3 0.4 0.5 1.1 0.6 0.3 0.6 0.5 0.1 0.0 0.0 0.0 0.9 0.4 0.1 0.2 0.0 0.5 0.5 0.4 2.6 0.0 0.0 0.0 0.0 2.4 0.4 1.9 0.0 0.0 0.0 0.3 0.8 0.6 0.0 9.0 0.3 0.0 3.8 1.4 1.5 0.5 0.0 5.9 0.4 0.3 2.3 0.0 0.3 1.6 0.0 2.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 7.1 0.1 0.1 0.0 0.0 2.1 0.2 0.3 0.0 0.0 0.3 0.0 0.2 0.8 1.1 2.9 2.5 0.4 0.8 1.3 0.3 3.2 0.3 KIF20A RAB6KIFL ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.1;lymphoid tissue: 24.6;testis: 11.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.0;Erythroid cells: 24.6;Extravillous trophoblasts: 13.1;Granulosa cells: 11.1;Spermatocytes: 21.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NK-cell: 6.6;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.6;T-cells: 2.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA036909, HPA036910" Approved Uncertain "Nucleoplasm,Cytokinetic bridge" Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytokinetic bridge" "HPA036909: AB_10670245, HPA036910: AB_10671716" "unprognostic (7.50e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-3)" "unprognostic (1.21e-2)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "prognostic unfavorable (2.14e-12)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.73e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (9.05e-2)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.16e-1)" 0.7 0.8 0.0 4.5 0.1 14.1 1.3 0.1 0.1 1.0 0.1 3.3 3.5 1.4 0.0 6.6 0.4 0.8 0.5 0.0 0.1 0.4 0.9 0.9 8.6 0.1 0.2 0.2 0.2 0.1 0.0 5.4 0.1 0.2 5.1 0.0 1.0 0.1 0.1 4.4 2.8 5.8 0.0 1.9 2.1 11.7 0.5 24.6 0.5 0.1 13.1 1.6 2.0 0.1 87.8 59.5 127.8 84.4 6.7 12.3 53.9 75.0 68.9 162.3 121.4 111.9 80.5 38.8 39.2 96.5 60.6 85.9 121.7 142.5 160.9 56.4 57.4 57.2 101.1 70.7 0.3 28.2 25.1 4.8 2.3 86.2 49.5 27.1 106.7 53.9 24.4 70.4 113.9 81.5 47.6 26.7 80.6 51.8 63.7 51.2 128.5 39.5 43.9 42.3 37.8 37.5 144.1 47.9 30.9 161.6 60.8 28.5 51.1 41.6 60.5 38.0 126.4 36.0 37.5 42.0 26.7 81.1 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 2.5 0.3 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.5 0.1 0.3 0.0 1.7 0.0 0.8 0.4 0.4 2.9 0.0 0.0 1.1 1.3 0.3 0.0 0.7 0.0 0.0 11.0 0.1 2.8 0.0 0.1 1.0 1.0 1.9 1.7 0.0 24.6 0.0 0.0 13.1 3.1 2.6 1.3 4.5 11.1 3.3 0.4 6.1 0.0 0.0 1.6 6.1 2.2 0.4 2.0 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 3.0 0.3 1.2 0.0 0.9 0.0 0.0 0.5 4.4 21.7 7.5 5.3 0.4 1.0 0.7 0.8 3.4 0.6 KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 12.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.6;Erythroid cells: 29.5;Extravillous trophoblasts: 11.5;Granulosa cells: 12.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034745, HPA034746, HPA061583" Approved Supported Nucleoplasm,Midbody Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Midbody" "HPA034745: AB_10670978, HPA034746: AB_10670173, HPA061583: AB_2684564" "unprognostic (8.17e-3)" "unprognostic (2.78e-2)" "unprognostic (1.02e-2)" "unprognostic (3.46e-3)" "unprognostic (3.20e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (7.37e-6)" "unprognostic (2.18e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (9.44e-6)" "unprognostic (3.79e-2)" "unprognostic (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" 0.3 0.3 0.3 3.2 0.2 11.2 0.7 0.1 0.3 0.6 0.3 3.7 3.1 0.8 0.0 3.6 1.5 0.5 0.2 0.2 0.5 0.2 0.5 0.5 5.5 0.9 0.7 0.1 0.1 0.1 0.5 2.3 0.6 0.1 4.5 0.6 0.5 0.1 0.1 2.2 3.3 1.3 0.7 2.4 1.7 1.5 0.6 12.6 0.2 0.0 6.6 0.9 1.1 0.2 60.2 41.1 61.0 30.1 2.9 5.1 24.0 44.7 23.8 59.7 51.6 46.7 34.3 36.7 27.4 22.1 46.2 35.1 66.6 24.2 66.8 42.5 33.4 41.7 50.1 33.4 0.7 46.7 27.8 1.7 1.5 49.6 28.2 7.3 37.0 27.7 53.8 79.1 57.0 38.7 43.0 23.1 61.7 63.8 43.2 47.1 82.2 34.6 14.5 23.4 40.1 33.5 72.9 30.5 18.6 30.6 24.5 18.1 26.0 39.3 50.6 42.6 54.1 22.6 41.7 52.0 20.8 50.4 60.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.1 0.3 0.2 0.5 0.9 0.7 0.6 0.7 0.6 0.2 0.1 0.0 0.5 1.3 1.3 1.8 0.3 1.4 0.6 0.2 1.1 0.8 0.4 1.5 0.2 0.0 0.0 7.0 0.9 2.2 0.0 0.0 0.4 18.6 1.5 1.3 1.2 29.5 1.9 0.0 11.5 2.1 3.1 1.6 0.0 12.2 1.1 0.1 5.3 0.0 1.9 4.6 2.0 1.3 0.7 0.8 0.0 1.4 0.0 0.0 0.2 3.1 0.0 2.0 0.7 0.1 0.1 0.0 8.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 2.9 8.7 5.4 7.2 0.3 1.8 1.8 1.3 6.6 0.5 KIF9 MGC104186 ENSG00000088727 "Kinesin family member 9" Q9HAQ2 3 47228395-47283451 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 64.4" "Cell type enhanced" "Detected in all" "Early spermatids: 690.3;Endometrial ciliated cells: 398.0;Respiratory ciliated cells: 359.0;Spermatocytes: 328.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022031, HPA022033, HPA030429" Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA022031: AB_1852502, HPA022033: AB_1852504, HPA030429: AB_10601921" "unprognostic (1.93e-2)" "unprognostic (6.37e-2)" "prognostic favorable (2.26e-4)" "unprognostic (1.17e-3)" "unprognostic (8.86e-2)" "unprognostic (1.13e-1)" "unprognostic (2.80e-3)" "unprognostic (1.70e-1)" "unprognostic (2.94e-2)" "unprognostic (4.59e-2)" "unprognostic (7.47e-2)" "unprognostic (1.14e-1)" "prognostic favorable (5.95e-6)" "unprognostic (4.21e-2)" "unprognostic (2.03e-1)" "unprognostic (9.17e-2)" "unprognostic (1.23e-1)" 6.5 7.4 9.3 3.1 10.1 11.8 10.6 8.8 14.4 7.6 23.1 9.1 6.1 7.9 20.5 5.8 26.3 6.4 14.1 10.1 9.8 26.8 6.0 8.6 2.6 12.0 12.9 5.0 12.7 10.1 16.4 3.7 11.4 7.7 8.1 18.7 8.9 4.8 9.4 8.4 5.6 4.5 11.0 5.7 9.3 64.4 10.0 2.3 21.0 5.7 3.1 6.8 5.4 9.5 19.4 21.7 7.6 19.1 3.6 8.7 6.2 5.9 6.1 8.8 7.8 8.4 23.0 12.8 7.3 7.6 11.8 12.0 22.6 15.3 8.7 6.6 14.6 11.9 16.5 26.9 3.4 25.3 3.8 4.5 15.3 12.8 9.6 7.4 19.0 13.5 26.5 5.1 6.6 15.5 13.7 37.6 21.7 44.4 30.5 8.6 5.3 18.3 36.7 10.9 10.8 19.9 6.8 13.0 21.8 3.9 8.4 17.6 9.0 5.1 11.0 8.3 13.6 4.4 19.7 16.1 18.9 25.1 11.3 2.5 3.6 2.1 1.5 2.6 3.0 3.5 1.4 2.3 5.7 0.6 1.7 1.9 6.3 3.5 2.3 3.3 1.0 1.3 9.3 10.1 8.8 14.4 10.1 9.8 12.0 12.9 11.4 11.0 10.0 9.5 34.5 19.2 18.4 4.2 6.7 20.1 53.7 44.3 20.5 7.2 61.4 74.5 28.2 38.6 51.9 64.4 35.5 10.7 7.5 23.8 109.5 45.5 690.3 398.0 17.8 29.3 58.9 20.0 16.6 32.7 11.1 12.1 34.1 38.5 29.1 11.3 17.9 20.7 9.2 5.0 10.3 40.1 52.9 7.2 7.1 160.6 14.0 8.0 16.0 2.8 3.8 17.2 3.1 2.5 3.2 26.0 15.7 13.2 5.7 37.6 15.1 198.1 359.0 44.0 13.1 42.2 16.7 328.8 37.3 17.2 20.2 8.2 7.8 21.8 37.8 37.4 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLF13 "BTEB3, FKLF-2, NSLP1, RFLAT-1" ENSG00000169926 "Kruppel like factor 13" Q9Y2Y9 15 31326835-31435665 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 275.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 85.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (2.13e-2)" "unprognostic (9.41e-2)" "unprognostic (5.50e-2)" "unprognostic (1.63e-3)" "unprognostic (3.10e-1)" "unprognostic (9.32e-2)" "unprognostic (2.96e-1)" "unprognostic (5.94e-2)" "unprognostic (1.15e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (2.09e-1)" "prognostic favorable (2.37e-9)" "unprognostic (2.16e-2)" "unprognostic (1.52e-1)" "unprognostic (1.62e-2)" "unprognostic (2.03e-2)" 25.0 11.7 2.8 13.0 8.2 62.0 19.3 16.8 13.7 13.3 0.0 21.5 15.1 17.5 8.6 18.5 21.0 2.7 27.7 10.0 0.0 17.4 20.5 31.8 17.7 5.7 3.4 14.2 44.3 10.9 11.6 4.8 4.6 9.9 13.5 3.9 12.8 10.7 38.6 33.7 29.2 20.8 0.0 29.6 22.6 6.7 16.9 48.8 28.3 18.8 18.1 15.2 13.0 20.8 10.7 0.9 14.8 6.0 34.3 18.2 1.3 10.5 16.7 5.7 6.9 8.8 7.4 2.1 21.5 19.8 18.6 16.1 4.1 12.6 4.3 50.9 3.5 25.6 27.6 7.0 49.3 23.3 33.1 10.7 85.8 4.6 31.9 9.4 0.2 17.3 11.2 5.2 2.9 3.3 32.2 28.1 2.9 42.5 21.0 18.4 14.6 17.3 11.2 4.6 16.7 36.5 13.4 21.6 0.0 17.7 3.3 13.6 22.3 4.3 11.6 16.7 0.1 32.3 19.2 6.6 3.7 34.6 5.1 2.2 4.7 7.0 13.1 2.3 13.8 26.5 7.7 12.6 1.2 24.2 6.7 21.0 8.6 1.5 1.9 21.0 21.3 4.3 2.8 8.2 16.8 13.7 10.0 0.0 5.7 3.4 4.6 0.0 16.9 20.8 56.6 131.4 66.0 7.5 65.4 58.5 32.9 20.2 33.0 34.7 18.9 22.1 47.9 50.1 24.8 16.5 0.0 14.7 149.3 74.0 9.8 19.2 7.7 49.5 36.2 45.1 40.6 74.5 18.6 26.5 25.0 46.0 24.5 67.1 26.6 13.3 42.5 102.5 11.6 275.9 9.1 39.1 10.2 84.8 28.5 6.5 25.4 34.4 32.0 4.7 90.7 28.7 120.5 12.1 40.6 29.8 22.4 46.6 150.0 40.5 56.7 26.0 9.5 12.3 26.3 68.6 52.5 1.5 8.2 35.1 51.3 14.6 82.1 54.2 45.8 44.1 KLHDC10 "KIAA0265, slim" ENSG00000128607 "Kelch domain containing 10" Q6PID8 7 130070534-130135705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020119 Approved Approved Nucleoplasm NA NA "Cluster 24: B-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA020119: AB_2249467" "unprognostic (2.83e-1)" "unprognostic (6.26e-2)" "unprognostic (1.13e-1)" "unprognostic (8.16e-3)" "unprognostic (3.22e-1)" "unprognostic (1.80e-2)" "unprognostic (5.55e-2)" "unprognostic (8.70e-2)" "unprognostic (7.97e-2)" "unprognostic (1.42e-2)" "unprognostic (8.69e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-2)" "unprognostic (8.22e-2)" "unprognostic (2.04e-1)" "unprognostic (2.23e-1)" "unprognostic (1.64e-2)" 12.3 17.3 19.4 9.5 19.8 7.9 14.6 27.0 17.2 12.4 21.6 12.8 11.1 13.0 13.7 12.6 14.9 9.5 13.5 18.5 26.3 21.2 23.2 11.9 8.4 17.4 25.1 14.4 15.4 30.7 14.0 13.9 21.5 12.6 12.7 15.4 10.6 12.2 24.0 13.2 10.4 11.5 16.5 10.8 11.7 38.0 31.1 11.8 18.1 22.0 9.3 8.6 8.9 15.8 24.5 22.5 15.3 83.8 19.9 21.8 7.0 22.9 17.5 17.1 17.7 12.4 18.3 20.7 15.8 21.2 28.4 18.8 24.6 14.6 21.4 16.9 14.8 12.2 24.7 14.6 15.6 22.5 14.4 13.8 24.8 26.2 16.4 21.2 24.4 14.2 59.9 12.7 19.4 20.7 19.5 21.9 2.6 18.0 14.6 15.8 28.6 15.1 23.5 16.7 24.6 19.7 36.8 65.2 18.5 18.5 15.9 16.6 27.7 21.8 9.5 29.5 27.6 16.7 23.6 19.2 45.7 21.4 30.0 0.0 0.4 0.5 0.6 0.6 0.5 0.4 0.4 0.7 0.5 1.1 0.3 0.7 0.4 0.1 0.5 0.4 0.9 0.1 19.4 19.8 27.0 17.2 18.5 26.3 17.4 25.1 21.5 16.5 31.1 15.8 18.6 19.2 20.2 53.8 9.7 23.2 7.8 13.6 14.2 20.1 31.0 20.1 23.1 30.0 19.7 35.0 39.6 11.3 12.6 18.2 3.9 18.3 66.7 31.2 24.9 19.0 19.9 18.7 85.7 23.8 9.6 22.2 13.3 18.4 6.3 19.6 37.9 42.3 12.2 35.3 86.1 15.8 20.3 23.0 12.8 17.4 15.2 11.7 17.8 72.1 15.5 18.4 7.2 82.4 59.9 20.5 9.2 24.5 9.8 13.0 16.2 27.5 27.2 22.1 0.0 30.6 14.7 36.2 6.3 17.5 29.1 11.2 9.6 22.7 20.4 12.2 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 KLHL8 KIAA1378 ENSG00000145332 "Kelch like family member 8" Q9P2G9 4 87160103-87240314 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 60.4" "Cell type enriched" "Detected in all" 4 "Muller glia cells: 216.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013856, HPA017762" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA013856: AB_1852594, HPA017762: AB_2669660" "unprognostic (2.93e-2)" "unprognostic (4.91e-3)" "unprognostic (3.44e-2)" "unprognostic (4.66e-2)" "unprognostic (1.18e-1)" "unprognostic (3.27e-2)" "unprognostic (2.12e-1)" "unprognostic (4.46e-3)" "unprognostic (3.27e-2)" "unprognostic (2.06e-2)" "unprognostic (1.13e-1)" "unprognostic (3.46e-1)" "prognostic favorable (1.53e-5)" "unprognostic (4.24e-3)" "unprognostic (3.05e-1)" "unprognostic (3.57e-3)" "unprognostic (1.57e-3)" 6.7 7.3 4.6 6.1 4.7 3.1 9.4 7.0 4.8 8.7 1.9 8.0 7.8 6.8 60.4 4.8 5.4 4.9 4.6 4.1 5.6 12.0 11.2 5.2 5.8 4.1 5.4 6.0 5.2 8.5 3.6 4.2 3.6 5.5 8.9 27.2 7.1 7.4 13.7 4.0 7.6 6.6 4.7 6.3 4.2 4.3 5.9 8.5 18.9 9.7 4.8 6.0 4.2 5.0 9.9 8.5 15.1 6.8 13.5 9.8 8.1 12.4 6.6 8.1 9.5 13.8 7.3 14.3 9.8 9.2 6.6 4.1 16.2 12.2 17.4 13.7 10.1 17.4 6.0 8.1 11.5 28.9 10.5 12.4 8.6 12.4 12.4 7.9 9.7 10.6 22.8 12.7 8.5 10.9 34.8 14.4 3.8 22.1 3.4 12.9 12.9 8.7 13.7 10.1 31.6 11.0 8.1 19.6 9.2 5.6 6.8 21.0 9.2 10.2 12.6 10.9 10.4 18.7 13.1 25.1 7.7 13.5 11.4 2.0 12.2 7.6 2.9 9.2 4.6 3.2 2.2 2.4 10.4 3.5 4.0 4.0 8.6 8.4 9.8 2.6 0.9 5.0 4.6 4.7 7.0 4.8 4.1 5.6 4.1 5.4 3.6 4.7 5.9 5.0 9.5 3.2 22.9 29.4 14.3 13.8 10.8 10.1 13.6 22.8 11.1 7.7 15.4 5.7 11.6 44.1 41.7 4.1 12.1 21.4 11.7 5.2 4.0 8.3 21.4 12.8 9.0 12.4 44.6 4.5 6.9 10.4 3.1 9.8 7.6 16.8 8.6 20.0 9.7 23.5 41.5 10.8 4.1 38.8 12.0 3.5 9.6 23.3 10.6 24.4 22.1 216.0 11.3 47.3 35.7 4.9 12.2 8.2 6.4 13.8 14.5 19.2 10.1 47.0 13.1 20.1 9.2 32.5 22.5 12.9 14.8 23.8 9.9 4.4 15.2 11.4 KLK11 "PRSS20, TLSP" ENSG00000167757 "Kallikrein related peptidase 11" Q9UBX7 19 51022216-51028039 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 324.2;skin 1: 239.8;vagina: 186.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 152.1;Club cells: 217.9;Late spermatids: 339.0;Prostatic glandular cells: 234.8;Squamous epithelial cells: 176.4;Suprabasal keratinocytes: 217.1;Urothelial cells: 186.1" "Cancer enhanced" "Detected in many" "prostate cancer: 53.3" "Region enhanced" "Detected in single" "hippocampal formation: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 13.0;HaCaT: 41.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB026340 Approved "Secreted in other tissues" NA NA 1800000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB026340: " "unprognostic (4.23e-2)" "unprognostic (1.50e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.78e-4)" "unprognostic (2.08e-2)" "unprognostic (4.67e-1)" "unprognostic (5.32e-2)" "unprognostic (3.72e-1)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.17e-4)" "unprognostic (2.92e-2)" "unprognostic (4.16e-6)" "unprognostic (3.90e-2)" "unprognostic (2.73e-1)" "unprognostic (4.40e-2)" "unprognostic (2.53e-1)" 28.4 0.2 0.0 0.4 0.0 0.0 17.1 0.9 0.1 109.8 44.5 1.9 0.7 7.2 2.6 324.2 34.2 59.3 2.0 1.7 0.0 0.3 0.8 18.9 0.0 0.2 0.1 1.6 89.1 0.0 8.8 0.0 0.3 64.9 0.6 0.7 169.5 4.2 1.9 239.8 1.4 0.3 0.0 0.1 113.3 14.4 0.6 2.5 0.4 0.3 27.2 1.4 186.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 6.4 0.1 13.0 0.0 0.0 41.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.7 0.0 0.2 0.1 0.3 0.0 0.6 0.0 0.2 86.6 10.4 0.0 0.4 106.9 152.1 131.6 13.1 0.2 33.4 35.3 0.8 88.6 217.9 0.0 0.0 0.0 0.0 0.1 0.0 9.2 111.6 4.7 1.1 3.8 20.3 0.0 0.0 130.2 0.0 9.1 91.3 15.6 1.3 0.0 0.0 0.0 0.3 0.0 0.0 10.7 118.0 0.0 11.4 339.0 2.8 1.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 79.4 0.0 0.4 0.5 234.8 0.1 0.0 26.9 1.3 0.0 0.2 7.9 2.1 2.5 176.4 217.1 0.0 1.7 0.0 0.4 186.1 KLK12 KLK-L5 ENSG00000186474 "Kallikrein related peptidase 12" Q9UKR0 19 51029092-51035230 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "cervix: 108.5;esophagus: 208.6;salivary gland: 64.7;vagina: 99.4" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Enteroendocrine cells: 40.3;Intestinal goblet cells: 24.9;Ionocytes: 14.2;Late spermatids: 34.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 17.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB025473 Uncertain "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB025473: " "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (1.08e-3)" "unprognostic (1.15e-1)" "unprognostic (5.80e-3)" "unprognostic (4.99e-3)" "unprognostic (3.18e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.56e-1)" "prognostic favorable (8.01e-4)" "unprognostic (8.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 108.5 2.2 2.1 4.0 0.0 0.0 208.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.1 0.5 0.8 0.0 64.7 0.0 0.0 0.6 5.8 0.1 0.0 0.0 0.4 0.5 0.0 0.1 0.1 0.0 8.9 0.0 99.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.5 0.5 0.2 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 30.7 0.0 0.0 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.9 14.2 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.2 8.4 0.0 0.0 0.0 0.0 1.3 1.7 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.3" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 1531.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 231.3" "Region enhanced" "Detected in some" "cerebellum: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 574.7;CAPAN-2: 501.6;HBEC3-KT: 2492.2;hTERT-HME1: 1487.5;RPTEC TERT1: 579.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004257, HPA024638, HPA046539, CAB078165" Enhanced Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" No No 130000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum, Golgi apparatus" "CAB004257: AB_627873, CAB078165: AB_2665800, HPA024638: AB_1852689, HPA046539: " "unprognostic (7.27e-3)" "unprognostic (7.21e-3)" "unprognostic (3.24e-1)" "unprognostic (6.20e-3)" "unprognostic (9.43e-2)" "unprognostic (4.94e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (1.25e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (7.11e-5)" "unprognostic (2.77e-1)" "unprognostic (7.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" 3.5 0.1 0.2 16.2 1.9 0.1 20.9 2.6 0.6 15.1 0.2 12.1 2.6 12.3 2.1 7.7 34.9 13.0 3.0 0.2 0.2 13.8 0.7 24.9 8.0 0.0 0.1 1.0 3.3 0.0 4.2 10.9 0.1 5.4 12.9 0.1 12.9 6.1 1.7 17.5 15.0 3.3 0.0 0.9 14.9 2.8 0.1 11.3 18.5 2.3 12.3 39.3 6.3 0.2 574.7 25.4 0.0 0.7 4.9 11.9 40.2 4.3 4.7 2.1 0.7 41.4 501.6 0.0 207.9 1.4 16.4 252.4 0.1 2492.2 2.7 0.7 0.2 0.0 0.5 0.1 1.2 0.0 0.2 6.1 189.7 6.0 1487.5 2.3 32.6 0.0 0.0 0.2 2.5 1.1 0.0 0.1 4.5 206.7 35.2 0.1 1.2 0.0 579.4 147.1 30.5 0.1 14.7 0.4 0.9 14.9 2.0 2.7 3.8 2.2 30.2 15.0 7.8 0.9 0.7 0.7 4.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 2.6 0.6 0.2 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 218.0 17.8 0.0 0.2 86.3 227.1 232.7 105.3 0.0 8.2 26.2 2.3 10.0 56.8 23.9 0.0 30.7 0.4 74.4 0.0 183.4 19.6 68.9 3.6 7.8 9.0 0.0 0.4 94.0 11.7 17.2 59.7 97.4 0.0 0.0 0.0 0.0 2.5 0.0 0.3 34.1 14.2 0.0 4.9 11.8 3.4 3.1 8.8 1.0 2.6 0.0 0.0 0.0 0.3 1531.1 91.2 0.4 0.3 302.0 16.7 0.2 69.3 0.0 0.0 3.4 9.6 3.6 1.0 60.3 29.7 83.3 5.3 0.1 15.3 169.9 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAMTOR3 "MAP2K1IP1, MAPBP, MAPKSP1, MP1, Ragulator3" ENSG00000109270 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3" Q9UHA4 4 99878336-99894428 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026858 Supported NA NA 120000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "HPA026858: AB_1853523" "unprognostic (7.77e-2)" "unprognostic (4.13e-2)" "unprognostic (3.07e-1)" "unprognostic (5.36e-3)" "unprognostic (3.96e-2)" "unprognostic (2.77e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.61e-2)" "unprognostic (3.20e-3)" "unprognostic (1.58e-1)" "unprognostic (5.57e-2)" "unprognostic (1.66e-1)" "prognostic favorable (1.75e-9)" "unprognostic (5.17e-2)" "unprognostic (1.66e-2)" "unprognostic (2.98e-1)" "unprognostic (1.40e-2)" 16.9 25.7 14.6 16.4 15.4 32.5 24.9 17.3 26.7 20.8 14.5 24.9 23.5 23.3 39.5 30.1 19.2 19.4 24.3 15.4 15.8 38.1 21.7 17.5 20.4 15.2 16.4 24.3 17.3 36.4 18.9 22.5 15.5 28.3 26.2 23.3 24.6 17.1 21.0 23.8 23.8 19.1 13.6 16.6 21.3 15.6 15.7 20.1 33.9 20.2 21.0 23.8 21.6 14.8 19.9 6.4 26.1 17.5 36.2 35.1 20.2 18.9 18.6 18.3 15.0 15.0 39.0 17.3 18.6 19.5 17.8 9.3 26.1 23.9 25.4 20.5 14.0 12.0 13.1 28.3 35.0 36.1 34.1 23.1 48.9 13.8 15.4 26.9 20.7 12.9 30.4 21.1 35.2 20.4 30.5 35.4 16.1 42.8 10.7 20.2 14.9 19.5 55.2 22.9 20.2 25.2 12.2 40.6 41.0 26.3 20.9 29.3 20.5 14.2 16.7 24.0 14.8 26.5 30.6 33.8 30.0 20.6 20.5 43.5 17.6 38.5 9.8 26.8 12.9 11.4 12.1 11.1 19.0 9.3 14.0 14.1 58.6 18.8 28.4 13.3 13.5 13.8 14.6 15.4 17.3 26.7 15.4 15.8 15.2 16.4 15.5 13.6 15.7 14.8 38.8 57.7 33.7 8.8 35.6 49.6 60.7 77.8 68.3 28.0 53.9 46.1 35.9 24.3 44.2 35.0 12.5 48.8 30.3 95.7 135.0 50.9 12.0 38.3 29.8 27.6 36.1 46.7 15.2 32.6 55.8 37.4 43.8 61.3 41.8 23.9 22.9 25.2 77.8 18.5 13.7 48.9 52.9 41.5 89.8 9.4 40.0 56.9 37.4 3.7 60.7 50.7 38.1 8.5 12.7 43.9 102.5 42.5 30.7 63.9 53.9 130.2 30.3 26.3 19.7 30.9 30.9 72.6 40.2 86.6 64.6 78.4 32.6 22.8 43.3 78.8 LARP7 "DKFZP564K112, HDCMA18P, PIP7S" ENSG00000174720 "La ribonucleoprotein 7, transcriptional regulator" Q4G0J3 4 112637107-112657592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Spermatogenesis, Transcription, Transcription regulation" RNA-binding "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026842, HPA027930" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "HPA026842: AB_10611116, HPA027930: AB_10601233" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (5.72e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (1.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (1.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (2.28e-2)" "prognostic favorable (4.33e-4)" 37.2 31.6 26.3 32.8 28.3 44.6 35.7 28.6 34.6 28.0 28.0 36.2 33.8 33.3 29.8 31.7 25.8 30.5 59.6 24.9 33.5 40.2 44.1 28.1 44.9 30.2 30.2 34.2 18.3 29.9 20.1 34.1 31.0 32.1 36.7 31.5 23.2 27.2 46.6 30.6 33.2 29.5 28.3 36.9 31.5 24.6 29.1 42.2 38.7 45.3 40.3 33.0 21.8 30.8 42.9 34.9 77.7 44.3 50.7 61.6 44.0 55.3 40.6 45.3 42.0 27.9 62.0 95.4 43.7 46.9 42.2 29.6 75.1 45.2 60.2 86.8 52.1 56.4 35.2 41.9 41.0 131.6 84.6 49.3 50.7 40.4 25.1 62.6 40.4 47.6 71.4 51.1 55.3 35.2 107.4 56.7 182.2 67.5 28.2 62.9 66.2 44.3 68.8 44.8 46.5 64.4 32.0 83.4 55.4 131.4 35.1 61.0 43.7 42.4 49.5 47.7 57.6 34.7 62.5 97.6 57.7 52.4 49.2 70.1 28.1 49.9 32.8 43.1 30.3 48.1 33.9 34.2 25.3 47.4 32.3 31.3 33.2 38.7 60.7 64.0 37.9 20.8 26.3 28.3 28.6 34.6 24.9 33.5 30.2 30.2 31.0 28.3 29.1 30.8 66.1 96.1 79.2 45.1 68.8 24.9 66.5 102.6 34.1 61.3 48.3 50.4 113.2 95.8 91.6 47.8 29.2 79.0 88.7 83.2 111.6 69.3 17.6 78.7 70.5 63.2 38.9 43.6 18.0 64.4 70.2 60.6 32.1 58.8 104.4 51.5 81.4 160.9 70.4 58.9 19.9 79.7 61.1 93.7 27.1 14.9 94.4 67.2 24.9 32.8 96.0 107.1 107.1 20.6 43.1 62.0 85.6 100.1 39.1 38.8 73.1 117.0 109.8 54.1 118.3 74.5 68.3 83.5 87.8 33.3 20.9 100.4 65.9 74.2 75.6 47.9 LARS2 "KIAA0028, LEURS, MGC26121, mtLeuRS" ENSG00000011376 "Leucyl-tRNA synthetase 2, mitochondrial" Q15031 3 45388561-45554726 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 35.4;Inhibitory neurons: 37.8;Oligodendrocyte precursor cells: 22.6;Oligodendrocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035951, HPA045450, HPA066085" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Nucleoplasm "HPA035951: AB_10672997, HPA045450: AB_2679328, HPA066085: AB_2685612" "unprognostic (3.89e-1)" "unprognostic (3.89e-1)" "prognostic favorable (1.71e-4)" "unprognostic (3.02e-2)" "unprognostic (3.77e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-3)" "unprognostic (9.19e-2)" "unprognostic (6.13e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-1)" "unprognostic (4.37e-2)" "prognostic favorable (1.32e-11)" "unprognostic (2.81e-1)" "unprognostic (5.74e-2)" "unprognostic (9.90e-2)" "unprognostic (9.07e-2)" 3.3 4.7 9.5 3.4 10.3 2.4 3.9 10.1 11.7 3.7 9.2 6.9 3.9 4.6 4.3 4.2 4.5 3.0 5.5 9.3 10.5 7.5 8.1 2.9 4.3 9.5 10.2 3.8 2.4 12.3 3.7 4.2 9.5 4.3 6.9 4.2 3.6 4.2 6.2 3.6 2.9 4.4 9.2 3.2 3.6 2.2 11.5 6.9 4.5 6.4 4.8 5.0 3.7 8.5 6.3 11.2 10.7 9.3 11.8 13.0 11.1 11.6 15.7 24.7 16.2 20.3 8.8 13.8 8.9 18.0 18.2 5.8 49.0 30.4 16.0 9.5 12.7 12.9 13.6 18.4 12.1 20.9 4.4 19.0 16.8 26.0 12.5 13.1 14.9 19.5 25.1 5.5 19.0 9.7 21.1 11.6 28.4 15.0 21.9 8.9 9.8 16.9 23.6 18.8 7.6 9.7 17.3 7.9 11.8 13.5 14.6 14.7 9.1 12.1 8.3 8.5 12.3 5.3 12.3 15.4 14.0 16.9 9.5 0.0 0.6 0.6 1.2 0.9 1.5 1.0 0.7 1.1 1.2 0.5 0.8 1.0 0.3 1.9 0.8 1.0 0.6 0.7 9.5 10.3 10.1 11.7 9.3 10.5 9.5 10.2 9.5 9.2 11.5 8.5 3.9 0.0 2.0 28.7 4.8 1.1 1.5 1.8 3.4 5.5 3.2 2.8 9.0 1.5 1.8 5.5 4.2 5.0 3.5 4.4 5.9 2.9 0.6 7.6 5.7 4.2 4.8 5.2 35.4 2.7 5.2 3.2 6.6 4.9 1.3 9.8 2.2 7.7 5.4 1.7 37.8 4.5 0.0 2.9 1.3 1.2 1.2 2.6 1.8 19.7 2.3 4.0 2.1 22.6 25.2 3.2 7.0 2.2 5.0 1.9 2.6 2.4 2.9 4.7 0.0 3.1 2.9 0.7 2.4 4.8 1.3 2.9 3.2 8.3 6.8 1.7 LCK ENSG00000182866 "LCK proto-oncogene, Src family tyrosine kinase" P06239 1 32251239-32286165 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "lymphoid tissue: 343.0" "Group enriched" "Detected in many" 9 "dendritic cells: 143.9;NK-cells: 272.9;T-cells: 255.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 12 "gdT-cell: 1109.8;MAIT T-cell: 1034.8;memory CD4 T-cell: 1123.8;memory CD8 T-cell: 1201.7;naive CD4 T-cell: 1260.7;naive CD8 T-cell: 1168.7;NK-cell: 641.5;T-reg: 1682.7" "Group enriched" "Detected in all" 12 "NK-cells: 641.5;T-cells: 1682.7" "Group enriched" "Detected in some" 6 "JURKAT: 365.7;MOLT-4: 536.9;U-698: 302.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA003494, CAB003816" Enhanced Approved "Golgi apparatus" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus" "CAB003816: AB_562158, HPA003494: AB_1852751" "unprognostic (6.38e-3)" "unprognostic (5.45e-3)" "unprognostic (8.39e-2)" "prognostic favorable (2.96e-6)" "unprognostic (2.20e-2)" "prognostic favorable (2.91e-4)" "unprognostic (4.78e-3)" "unprognostic (1.33e-2)" "prognostic favorable (5.65e-5)" "unprognostic (3.07e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (8.15e-2)" "unprognostic (4.05e-2)" "unprognostic (7.39e-2)" "unprognostic (1.17e-2)" 3.4 2.2 0.4 50.6 0.5 13.7 2.3 0.4 0.5 2.2 0.7 6.9 7.6 1.7 13.0 3.9 2.1 9.4 1.9 0.5 0.4 3.8 3.8 11.4 111.0 0.8 0.5 1.6 0.9 0.5 0.8 1.1 0.6 2.8 6.5 0.0 4.8 1.4 1.3 1.9 23.1 2.3 0.6 39.9 12.1 1.1 0.5 343.0 3.7 1.4 79.6 13.2 2.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.7 64.1 3.5 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.6 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 365.7 0.2 0.0 0.0 0.0 536.9 0.2 5.9 4.6 0.3 20.6 0.1 0.3 0.3 0.2 0.1 0.0 0.1 0.3 0.3 0.4 0.6 0.4 0.0 0.0 1.7 0.1 0.1 0.7 0.3 302.7 0.0 0.1 0.0 12.8 5.2 6.0 1109.8 4.9 1034.8 62.0 1123.8 1201.7 5.2 98.9 1260.7 1168.7 33.6 641.5 6.0 7.7 1682.7 1836.9 0.4 0.5 0.4 0.5 0.5 0.4 0.8 0.5 0.6 0.6 0.5 0.6 4.9 0.0 9.3 0.0 23.4 4.6 1.2 0.4 0.0 0.0 3.5 5.2 1.8 4.3 1.6 3.7 0.0 0.3 143.9 0.9 0.0 0.6 0.1 1.0 0.5 3.4 2.4 10.1 0.2 0.5 0.2 3.1 7.7 0.7 5.1 0.0 4.6 1.5 0.3 0.0 0.2 0.3 0.0 7.8 7.3 0.0 0.0 8.1 3.6 0.0 8.7 0.0 272.9 0.5 0.1 4.7 0.0 0.4 15.7 1.0 0.0 1.4 1.8 0.0 0.0 1.5 2.4 4.5 2.0 0.5 3.1 0.4 255.5 2.9 1.3 1.1 LDOC1 "BCUR1, Mar7, Mart7, RTL7, SIRH7" ENSG00000182195 "LDOC1 regulator of NFKB signaling" O95751 X 141111605-141177129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 123.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Proximal tubular cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 24.7;MCF7: 31.9;PC-3: 34.3;U-251 MG: 21.9" "Region enriched" "Detected in many" 5 "cerebellum: 19.2" "HPA051768, HPA061842" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Nucleoli" "HPA051768: AB_2681599, HPA061842: AB_2684624" "unprognostic (4.09e-1)" "unprognostic (4.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.42e-1)" "unprognostic (4.51e-2)" "unprognostic (2.08e-2)" "unprognostic (8.92e-2)" "unprognostic (1.21e-1)" "unprognostic (6.40e-3)" "unprognostic (1.21e-1)" "unprognostic (1.27e-2)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (4.38e-3)" "unprognostic (2.76e-2)" 32.3 34.0 4.7 0.9 5.5 0.1 28.0 2.9 8.5 45.8 0.2 18.8 0.9 53.9 1.8 21.4 48.5 1.6 15.1 6.2 5.8 33.2 4.8 19.6 0.8 5.3 5.0 46.8 19.3 10.5 123.3 0.0 5.0 34.3 0.3 3.4 55.1 5.9 5.5 31.5 12.5 2.0 1.2 14.2 18.4 10.8 5.0 0.9 53.7 0.4 0.7 33.1 30.6 6.0 0.0 24.7 3.0 8.4 5.0 6.2 0.0 5.0 5.8 6.3 8.8 0.0 8.0 0.0 4.2 7.7 6.1 10.4 3.4 7.1 4.5 0.0 6.6 0.0 11.7 0.0 2.0 0.0 1.9 10.9 3.6 5.5 2.9 5.1 5.7 0.0 0.1 0.0 5.7 31.9 0.0 0.0 3.3 0.0 34.3 0.0 2.7 0.0 7.7 4.7 0.0 3.2 0.0 4.0 0.0 1.6 5.1 0.0 11.9 0.0 6.8 0.0 21.9 0.0 0.0 0.0 3.5 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.8 0.9 2.5 0.8 0.2 2.1 2.2 1.4 0.0 6.4 0.0 1.4 2.6 1.0 4.7 5.5 2.9 8.5 6.2 5.8 5.3 5.0 5.0 1.2 5.0 6.0 8.6 0.0 5.3 4.2 4.9 6.0 16.8 4.6 16.5 29.3 23.8 20.2 2.2 30.0 8.2 23.9 8.4 2.8 5.7 0.1 43.0 13.8 0.7 7.8 13.5 12.8 5.4 0.8 9.4 14.0 1.8 16.1 3.6 6.0 2.5 8.8 12.8 0.1 0.9 20.2 9.9 0.4 8.2 0.3 1.8 1.1 22.1 1.0 3.6 7.5 0.3 21.2 5.2 7.1 15.0 13.7 0.2 38.7 0.9 11.9 0.0 43.8 4.6 13.0 13.1 15.3 26.2 0.9 7.6 16.7 6.8 1.5 5.2 13.5 0.3 15.0 LILRA2 "CD85h, ILT1, LIR-7, LIR7" ENSG00000239998 "Leukocyte immunoglobulin like receptor A2" Q8N149 19 54572920-54590287 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.5;lymphoid tissue: 57.4" "Group enriched" "Detected in some" 5 "Hofbauer cells: 22.0;Kupffer cells: 79.9;Macrophages: 39.1;monocytes: 48.7" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 31.6" "Group enriched" "Detected in many" 6 "granulocytes: 31.6;monocytes: 11.6" "Cell line enhanced" "Detected in some" "NB-4: 1.7;REH: 2.0;THP-1: 4.0;U-937: 9.1" "Secreted to blood" NA NA 140000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.04e-1)" "unprognostic (7.72e-2)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (2.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-1)" "unprognostic (3.53e-5)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (5.43e-2)" "unprognostic (5.58e-2)" "unprognostic (3.30e-4)" "unprognostic (4.21e-2)" "unprognostic (6.59e-2)" 5.2 3.2 0.9 2.8 1.0 15.5 1.8 1.0 1.5 0.9 0.9 1.5 0.2 1.0 0.2 0.9 4.0 0.4 1.9 1.0 1.0 1.4 3.4 10.3 0.2 2.0 1.2 0.8 1.4 0.1 0.8 0.1 2.0 1.4 0.2 0.2 1.7 0.1 0.5 0.7 1.7 0.4 1.1 57.4 1.6 0.8 1.6 0.2 0.8 0.2 0.3 2.2 1.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.1 0.0 5.3 7.6 3.0 0.1 11.6 0.1 0.1 0.1 0.1 3.3 0.3 0.1 0.1 31.6 0.4 11.3 0.7 0.1 6.1 0.9 1.0 1.0 1.5 1.0 1.0 2.0 1.2 2.0 1.1 1.6 1.8 0.2 3.2 3.0 0.0 0.3 0.3 1.6 0.0 0.0 0.9 0.4 0.1 0.5 1.5 1.8 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.8 0.0 0.2 0.2 0.6 0.0 0.1 6.3 0.1 0.4 0.4 22.0 0.0 0.0 0.0 0.0 79.9 5.9 0.6 0.0 39.1 0.0 8.4 48.7 0.0 2.1 0.0 0.1 0.0 0.0 0.0 1.1 1.0 0.0 0.1 1.5 0.6 0.0 2.1 0.3 0.3 0.3 0.0 0.1 0.4 1.4 0.0 0.0 0.6 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 LMAN2 "C5orf8, GP36B, VIP36" ENSG00000169223 "Lectin, mannose binding 2" Q12907 5 177331567-177351668 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 530.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003927 Approved NA NA 88000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA003927: AB_1079257" "unprognostic (5.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.87e-2)" "unprognostic (1.85e-3)" "unprognostic (6.25e-2)" "unprognostic (3.90e-3)" "unprognostic (2.88e-3)" "unprognostic (2.06e-2)" "unprognostic (2.08e-1)" "unprognostic (1.51e-3)" "unprognostic (4.56e-2)" "unprognostic (6.67e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (4.43e-2)" "unprognostic (6.13e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-1)" 72.0 79.5 40.1 63.2 43.5 77.6 65.3 42.4 49.3 76.7 62.6 77.0 91.4 74.0 136.1 147.1 70.3 57.0 74.7 44.5 43.0 85.5 207.8 78.8 66.2 45.2 41.5 69.6 155.9 49.9 60.8 72.6 43.1 64.7 40.1 14.7 117.9 48.7 50.6 64.6 81.2 36.2 41.7 86.9 82.4 93.5 46.4 54.8 97.2 29.2 42.7 67.0 73.1 43.6 108.6 196.4 57.3 317.9 201.5 76.2 298.0 122.1 120.8 105.6 132.9 326.2 254.0 115.9 286.2 162.7 196.3 163.9 69.6 242.9 39.6 556.7 166.6 73.9 136.7 196.5 196.2 155.4 210.7 140.5 94.2 106.0 94.8 118.3 142.3 100.3 90.8 452.0 79.3 318.5 115.8 268.3 82.7 159.7 174.8 132.4 97.6 404.9 99.5 122.6 94.9 105.4 113.3 191.9 205.0 51.9 150.4 349.5 145.5 168.2 108.0 89.2 182.7 252.0 200.8 114.8 234.5 217.8 186.6 569.9 411.8 476.9 408.9 379.2 349.7 252.1 295.6 342.9 358.8 256.6 241.0 280.7 552.6 364.8 346.1 500.9 350.2 828.4 40.1 43.5 42.4 49.3 44.5 43.0 45.2 41.5 43.1 41.7 46.4 43.6 82.7 57.7 74.5 12.1 114.8 57.0 147.9 384.3 47.8 33.2 100.9 74.4 44.6 124.4 229.9 108.5 16.7 312.7 147.4 168.3 52.8 233.2 103.8 87.2 99.5 99.5 58.9 71.8 7.0 237.3 444.4 120.4 70.8 131.2 77.4 97.2 81.8 223.4 240.4 55.5 8.3 190.0 266.5 105.0 85.3 28.2 88.0 107.4 120.9 13.1 116.4 89.0 162.7 13.0 9.7 226.1 130.9 63.9 388.4 146.1 186.1 111.9 151.9 46.5 65.7 70.8 108.9 275.8 192.0 134.1 69.9 530.3 112.5 111.8 160.6 165.6 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 33.3 49.4 10.3 11.5 10.8 4.2 31.4 20.7 17.0 28.9 13.3 26.4 13.5 22.5 27.7 25.7 26.3 16.0 27.7 11.1 11.5 53.0 42.9 27.9 12.1 13.6 11.9 34.5 36.5 31.7 26.5 17.2 12.3 19.1 20.5 10.7 33.2 20.0 28.8 28.1 28.6 12.7 11.4 21.8 29.6 10.4 10.2 9.1 35.1 13.1 16.8 30.1 29.4 16.1 3.8 3.8 6.0 10.2 16.5 23.7 17.9 2.2 7.1 2.6 5.6 4.8 8.2 6.5 9.2 8.8 5.8 7.5 3.8 9.8 2.4 16.3 11.9 6.2 4.9 7.8 13.7 3.4 8.7 7.6 9.6 0.8 5.7 19.1 7.4 5.5 9.4 6.1 6.0 8.1 2.5 4.7 4.6 8.5 4.8 0.3 15.4 37.8 17.0 13.8 5.5 8.5 0.9 7.0 13.3 3.0 4.6 25.3 1.1 3.9 4.6 4.3 2.8 8.8 5.5 2.8 2.3 4.0 12.3 6.5 2.2 3.9 2.0 2.5 2.5 12.1 2.9 1.9 1.7 21.0 3.1 2.3 11.4 2.6 4.8 2.2 3.7 2.1 10.3 10.8 20.7 17.0 11.1 11.5 13.6 11.9 12.3 11.4 10.2 16.1 49.7 64.1 38.3 82.3 93.4 29.1 41.9 45.2 71.2 73.7 39.2 25.4 40.6 50.1 56.0 58.8 110.5 69.6 36.2 79.0 19.6 49.0 28.8 48.3 22.7 41.1 18.7 18.5 119.2 49.6 59.2 56.1 36.7 61.7 40.5 15.7 44.6 60.5 42.1 55.5 144.6 37.6 44.7 66.9 36.3 9.3 35.4 52.0 32.0 79.6 49.3 56.3 28.8 122.2 156.6 42.0 51.0 33.8 82.7 19.6 78.7 64.1 65.5 90.8 26.3 36.4 33.9 22.5 16.9 43.4 38.1 77.4 43.2 26.9 31.7 34.2 LPGAT1 "FAM34A, FAM34A1, KIAA0205, NET8" ENSG00000123684 "Lysophosphatidylglycerol acyltransferase 1" Q92604 1 211743457-211830763 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 416.1;Oligodendrocytes: 474.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (3.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (9.47e-3)" "unprognostic (1.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.67e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.70e-2)" 20.0 19.7 17.0 13.4 29.4 20.0 13.4 13.8 19.5 11.4 21.3 9.3 23.6 9.0 10.1 7.7 8.5 12.1 11.8 14.6 18.0 9.8 36.4 8.8 10.5 18.2 22.4 6.0 13.7 13.9 8.9 9.1 17.8 10.1 10.3 41.1 9.4 12.4 9.9 6.2 35.0 12.2 13.2 16.7 7.4 22.3 21.7 8.2 25.8 14.9 9.8 13.8 7.4 39.2 28.2 30.4 9.8 23.5 17.4 24.2 14.1 19.7 31.2 18.0 16.5 9.1 22.9 11.5 11.3 30.7 20.1 15.0 33.2 17.6 22.6 22.6 11.2 12.0 24.5 20.8 20.9 29.9 19.8 14.3 21.2 16.6 21.6 33.1 21.9 16.2 14.0 0.2 24.1 8.8 11.4 11.1 10.7 12.0 4.9 27.2 38.8 3.5 20.1 23.0 56.6 29.3 32.3 33.9 33.9 15.1 17.3 19.3 21.3 32.7 14.4 30.3 32.5 16.1 21.2 30.2 16.2 25.0 22.8 12.3 2.7 16.1 1.4 2.2 1.1 1.8 0.9 1.0 3.2 1.0 0.2 0.8 12.1 5.3 1.7 2.4 0.2 0.9 17.0 29.4 13.8 19.5 14.6 18.0 18.2 22.4 17.8 13.2 21.7 39.2 50.0 28.9 21.0 28.7 42.2 12.2 77.7 11.5 38.1 206.3 32.2 18.9 40.4 72.9 16.9 12.9 62.6 2.3 73.2 25.3 1.9 71.9 416.1 39.1 39.2 31.6 13.8 15.3 73.5 59.4 4.7 30.9 19.9 28.0 12.7 22.0 25.0 56.2 20.9 35.3 92.3 14.6 26.4 49.7 27.3 60.2 47.2 44.9 30.2 46.9 58.6 34.7 49.4 70.4 474.0 47.8 19.5 55.7 15.0 53.3 126.1 24.2 38.2 127.6 19.7 47.1 33.2 67.2 33.3 30.7 7.5 1.1 32.5 129.4 23.4 63.1 LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 11 "NTERA-2: 15.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA070726 Uncertain "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Endoplasmic reticulum" "HPA070726: " "unprognostic (3.64e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-1)" "unprognostic (4.75e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.48e-1)" "unprognostic (2.24e-1)" "unprognostic (2.65e-1)" "unprognostic (9.25e-2)" "unprognostic (1.03e-4)" "unprognostic (4.49e-6)" "unprognostic (6.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" 0.2 0.2 0.6 0.2 0.7 0.5 0.4 0.7 2.6 0.2 1.6 0.5 1.2 0.1 0.3 0.0 0.2 0.5 0.1 0.7 1.2 0.1 2.1 0.3 0.1 1.0 1.1 0.3 0.8 0.2 0.2 0.1 1.3 0.4 0.1 1.0 0.1 0.5 0.8 0.4 1.6 0.1 0.7 0.1 0.3 0.8 0.7 0.0 1.5 0.0 0.1 0.1 0.1 0.9 0.5 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 15.3 0.0 0.0 0.0 0.0 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.6 1.9 0.1 0.1 0.6 0.1 0.1 0.1 0.1 1.5 0.2 0.1 0.1 0.8 0.2 0.2 0.2 0.1 2.2 0.6 0.7 0.7 2.6 0.7 1.2 1.0 1.1 1.3 0.7 0.7 0.9 0.2 0.0 4.4 4.6 0.1 1.1 4.4 4.0 0.6 0.5 8.6 9.1 0.3 11.5 1.7 0.0 0.0 0.1 0.3 0.8 3.9 1.2 15.2 0.9 0.5 0.3 0.0 0.0 2.2 0.8 0.1 1.5 2.0 2.2 0.0 104.4 1.4 2.2 0.1 0.0 0.6 0.9 2.0 0.8 2.8 3.2 0.0 0.3 5.4 0.0 0.0 3.9 0.0 1.0 2.2 1.2 0.0 0.0 0.0 2.4 12.3 1.0 0.9 0.8 0.0 1.4 8.1 10.5 4.7 1.4 1.1 0.3 0.6 0.0 1.2 0.6 LRBA "BGL, CDC4L, LAB300, LBA" ENSG00000198589 "LPS responsive beige-like anchor protein" P50851 4 150264435-151015727 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 213.7;Inhibitory neurons: 192.6;Microglial cells: 161.1;Oligodendrocyte precursor cells: 239.8;Oligodendrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019366, HPA023597" Approved Approved "Golgi apparatus,Cytosol" NA NA 340000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" Cytosol "HPA019366: AB_2138441, HPA023597: AB_1853256" "unprognostic (2.60e-1)" "unprognostic (4.70e-2)" "unprognostic (1.64e-3)" "unprognostic (4.49e-3)" "unprognostic (4.38e-1)" "unprognostic (8.65e-2)" "unprognostic (5.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.29e-2)" "unprognostic (5.88e-2)" "prognostic favorable (2.22e-16)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (4.79e-1)" "unprognostic (3.00e-1)" 7.3 10.7 3.4 9.3 6.9 11.1 22.7 11.1 3.8 13.1 18.6 16.7 13.3 6.9 14.2 13.9 15.2 9.9 8.3 2.9 2.2 23.5 13.4 11.0 15.8 5.1 4.5 8.9 13.5 34.2 6.5 7.0 6.1 20.0 17.4 14.9 13.8 8.9 7.2 19.3 11.5 6.6 3.4 9.6 17.0 9.4 3.7 18.7 19.1 8.9 17.7 12.3 7.0 6.3 27.6 14.3 11.9 11.1 12.2 18.5 17.0 6.0 15.8 10.9 10.2 30.9 35.6 33.7 7.2 8.6 7.5 13.7 22.1 36.6 15.3 25.9 15.8 20.8 19.8 19.0 7.5 29.0 16.2 14.6 21.1 16.0 24.6 23.9 32.9 14.8 22.4 24.3 12.9 21.9 21.9 7.7 10.7 23.7 10.3 18.4 12.0 12.6 42.0 33.7 39.3 13.0 15.1 32.1 7.4 18.1 32.4 6.1 17.2 16.8 12.2 8.7 11.4 20.9 20.5 20.5 26.2 16.0 6.6 5.7 0.6 1.2 5.0 0.2 3.3 4.9 3.3 4.7 1.0 2.1 2.3 4.0 0.1 3.2 2.1 2.1 4.6 1.8 3.4 6.9 11.1 3.8 2.9 2.2 5.1 4.5 6.1 3.4 3.7 6.3 10.4 16.0 14.9 148.5 42.5 17.5 16.4 21.0 28.5 33.5 30.8 18.2 55.9 21.5 21.5 51.5 148.0 23.7 37.7 19.7 9.8 15.2 25.5 51.2 11.0 13.3 42.0 40.2 213.7 13.5 10.6 12.8 56.6 61.8 6.3 22.4 10.0 20.5 6.1 30.3 192.6 23.8 24.4 11.1 12.8 5.5 9.6 17.7 16.0 161.1 8.2 17.7 46.4 239.8 217.4 17.2 20.2 10.1 38.3 22.4 22.0 15.8 36.7 72.6 6.6 13.7 9.8 16.6 22.3 37.3 23.7 24.2 45.6 25.9 27.2 24.0 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRPAP1 "A2MRAP, HBP44, RAP" ENSG00000163956 "LDL receptor related protein associated protein 1" P30533 4 3503612-3532446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 584.3;Syncytiotrophoblasts: 693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008001, CAB025518" Enhanced Supported Supported "Endoplasmic reticulum" NA NA 810000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Endoplasmic reticulum" "CAB025518: , HPA008001: AB_1853292" "unprognostic (3.20e-3)" "unprognostic (7.01e-2)" "unprognostic (2.30e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-2)" "unprognostic (9.61e-2)" "unprognostic (1.01e-2)" "unprognostic (3.89e-3)" "unprognostic (8.58e-2)" "unprognostic (6.12e-2)" "unprognostic (2.14e-3)" "unprognostic (2.19e-1)" "prognostic favorable (4.67e-11)" "unprognostic (6.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.58e-1)" "unprognostic (5.61e-2)" 6.6 9.0 6.6 2.6 10.3 6.0 6.4 8.6 7.6 8.9 10.7 7.6 3.3 8.6 3.2 5.8 7.5 1.9 19.3 5.8 8.1 12.7 9.6 8.5 2.1 8.0 6.9 9.5 14.4 7.7 14.4 6.3 7.9 8.2 1.7 2.8 10.1 4.1 8.9 6.3 6.7 1.9 5.2 8.6 9.2 9.2 7.5 1.6 8.9 2.4 1.4 7.3 6.3 6.3 3.7 7.4 5.7 8.2 5.5 2.9 12.5 5.9 4.8 4.3 3.1 14.9 7.0 2.1 6.0 4.2 7.0 6.2 3.4 5.8 2.4 1.6 7.9 2.9 7.8 10.4 4.2 4.7 12.5 4.0 4.3 3.9 1.9 4.7 5.2 3.9 5.1 7.0 3.6 5.9 3.1 18.4 4.9 5.1 7.8 4.3 4.2 7.1 4.8 8.6 5.6 4.6 7.4 3.0 8.1 3.4 6.7 8.6 5.6 5.1 4.7 4.1 8.2 4.2 2.9 2.8 5.9 13.3 7.2 21.9 23.2 60.1 9.3 19.7 8.1 9.9 8.6 8.8 13.3 10.0 9.4 8.6 20.5 11.7 19.1 10.2 11.5 27.3 6.6 10.3 8.6 7.6 5.8 8.1 8.0 6.9 7.9 5.2 7.5 6.3 95.0 109.0 90.9 21.2 78.0 67.8 174.6 267.7 52.9 70.6 75.3 84.2 165.9 108.7 158.7 195.0 45.9 584.3 75.8 147.7 50.9 159.3 40.4 85.5 229.6 88.2 82.6 35.7 22.5 107.9 184.0 152.5 79.0 71.2 81.1 102.3 62.4 92.6 243.1 38.7 20.6 121.6 164.8 100.5 80.2 60.0 126.2 154.2 147.7 16.9 107.1 140.0 91.6 28.1 16.7 95.4 153.4 151.6 205.2 124.5 204.6 273.7 144.8 86.2 78.9 82.8 108.1 272.5 161.4 40.7 61.4 693.5 86.0 99.9 109.9 140.5 LRRC25 "FLJ38116, MAPA" ENSG00000175489 "Leucine rich repeat containing 25" Q8N386 19 18391137-18397622 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 32.4;lymphoid tissue: 61.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 47.0;Kupffer cells: 123.6;Macrophages: 90.0;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 320.6;eosinophil: 356.2;intermediate monocyte: 512.1;myeloid DC: 229.3;neutrophil: 573.0;non-classical monocyte: 706.7" "Group enriched" "Detected in all" 60 "dendritic cells: 229.3;granulocytes: 573.0;monocytes: 706.7" "Cell line enhanced" "Detected in some" "Hep G2: 1.0;HMC-1: 1.8;THP-1: 1.7;U-937: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029459 Approved Approved "Endoplasmic reticulum,Microtubules,Cytosol" NA NA 630000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Endoplasmic reticulum, Microtubules, Cytosol" "HPA029459: AB_10610005" "unprognostic (2.72e-2)" "unprognostic (6.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.07e-1)" "unprognostic (3.77e-2)" "unprognostic (9.15e-2)" "unprognostic (5.80e-2)" "unprognostic (1.23e-1)" "unprognostic (1.20e-2)" "unprognostic (4.63e-2)" "unprognostic (2.02e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-3)" "unprognostic (5.77e-2)" "prognostic unfavorable (6.93e-4)" "unprognostic (1.74e-1)" "unprognostic (1.14e-1)" 9.4 9.4 2.4 21.8 2.5 32.4 3.1 3.3 2.9 1.8 3.2 3.3 3.7 1.6 0.7 2.3 3.9 5.3 2.5 2.3 3.1 2.4 5.9 11.5 9.9 4.6 4.0 1.5 2.0 0.7 1.2 5.4 4.2 2.0 2.8 0.3 2.6 1.2 3.7 1.0 4.8 6.7 2.8 61.2 2.3 1.2 5.4 3.0 1.2 8.7 4.0 7.0 1.3 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 1.0 0.8 0.4 1.8 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.7 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 1.5 0.1 55.4 320.6 356.2 0.9 512.1 1.9 7.3 0.6 0.7 229.3 8.4 0.5 0.6 573.0 4.6 706.7 32.1 1.3 229.2 2.4 2.5 3.3 2.9 2.3 3.1 4.6 4.0 4.2 2.8 5.4 4.7 0.7 0.0 1.3 0.0 5.0 0.0 0.1 0.1 0.0 0.1 0.3 1.0 0.3 0.0 0.7 0.0 0.0 0.1 2.9 0.1 5.9 0.1 1.9 0.2 0.1 0.9 0.0 2.1 0.1 0.0 0.4 0.5 0.0 0.4 10.2 0.0 1.8 0.5 47.0 0.0 0.1 0.0 0.0 123.6 12.5 0.5 0.0 90.0 1.8 1.0 74.9 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 2.4 0.2 0.0 0.2 0.0 0.1 0.4 1.1 0.2 0.1 0.1 LRRC61 "FLJ31392, HSPC295, MGC3036" ENSG00000127399 "Leucine rich repeat containing 61" Q9BV99 7 150323263-150338156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 48.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 80.6;Hep G2: 53.3;NTERA-2: 67.0" "Low region specificity" "Detected in all" HPA019355 Approved Approved Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA019355: AB_1853339" "unprognostic (4.05e-2)" "unprognostic (9.50e-2)" "unprognostic (1.61e-3)" "unprognostic (5.91e-3)" "prognostic unfavorable (1.11e-5)" "unprognostic (1.46e-2)" "unprognostic (4.43e-3)" "unprognostic (1.82e-1)" "unprognostic (1.76e-2)" "unprognostic (4.22e-2)" "unprognostic (2.53e-2)" "unprognostic (1.56e-1)" "unprognostic (1.66e-2)" "prognostic favorable (2.85e-4)" "unprognostic (1.21e-1)" "unprognostic (3.27e-1)" "unprognostic (1.69e-3)" 4.0 18.3 9.5 4.5 8.4 1.6 4.5 6.9 8.7 7.5 9.8 5.7 4.3 6.5 2.0 8.8 14.5 4.0 4.1 7.7 13.1 12.1 23.4 4.4 7.3 9.7 10.1 15.2 11.2 11.4 13.5 3.8 10.4 6.6 1.9 2.8 5.3 4.3 2.2 6.8 5.8 2.0 8.2 6.1 6.1 9.1 13.4 11.5 8.7 2.3 3.9 4.7 6.5 6.7 20.0 0.5 0.6 0.1 0.0 0.0 9.0 0.2 0.0 2.4 7.8 37.9 19.4 6.2 8.2 0.3 0.0 17.6 0.0 0.0 1.3 80.6 24.4 7.4 23.5 53.3 13.8 0.0 3.7 1.6 7.9 0.0 0.0 0.6 0.1 40.2 25.9 11.5 0.0 36.5 37.5 3.2 67.0 13.8 0.0 0.0 0.1 16.5 5.7 13.2 34.6 33.4 33.6 7.2 13.7 5.6 5.6 4.5 0.1 0.0 0.1 0.0 0.1 12.5 4.4 0.0 0.0 0.0 0.0 2.8 2.9 8.5 10.8 1.1 8.3 8.7 7.3 8.2 3.0 10.7 7.0 8.4 13.1 8.7 1.3 17.9 12.7 5.7 9.5 8.4 6.9 8.7 7.7 13.1 9.7 10.1 10.4 8.2 13.4 6.7 0.3 6.4 1.5 2.3 7.1 1.1 4.7 16.5 8.6 7.8 8.0 8.9 2.2 11.5 6.8 16.5 0.0 25.2 11.1 9.4 19.6 27.3 5.7 20.9 1.6 1.7 19.3 3.8 1.7 28.4 24.5 4.7 7.1 5.8 1.3 22.9 1.8 22.6 6.0 13.5 3.6 6.7 18.3 1.3 0.0 16.3 10.2 3.3 3.6 0.0 16.5 13.7 11.3 4.5 0.3 27.9 11.2 5.7 3.5 4.0 11.7 48.7 20.1 4.5 0.0 5.3 3.2 20.8 23.7 8.1 2.7 27.0 7.4 9.0 10.6 3.0 LSM14A "C19orf13, DKFZP434D1335, FAM61A, RAP55, RAP55A" ENSG00000257103 "LSM14A mRNA processing body assembly factor" Q8ND56 19 34172504-34229288 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Repressor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017961 Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 18000 "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" "Cytoplasmic bodies" Cytosol "HPA017961: AB_1845610" "unprognostic (2.38e-1)" "unprognostic (3.30e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.01e-2)" "unprognostic (2.45e-3)" "unprognostic (1.88e-1)" "unprognostic (9.62e-3)" "unprognostic (5.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (4.98e-2)" "unprognostic (4.17e-2)" "unprognostic (2.52e-2)" "unprognostic (5.55e-2)" "unprognostic (1.56e-1)" 43.9 38.5 26.4 27.5 26.2 72.0 42.0 28.0 39.2 46.2 29.4 49.4 24.8 47.8 31.7 41.2 40.6 22.7 36.4 25.5 26.0 37.7 37.6 37.7 46.5 26.1 27.1 51.7 32.9 33.8 30.4 37.5 26.4 36.5 29.2 52.8 36.4 32.3 74.2 47.1 38.2 33.0 28.3 36.7 32.8 33.1 26.1 50.7 45.9 43.7 40.8 44.2 41.8 27.7 66.0 46.1 62.9 49.7 33.4 42.9 20.4 24.7 39.5 43.9 42.9 50.2 27.7 107.9 28.9 46.7 14.7 17.6 57.0 42.7 70.8 71.5 10.4 102.2 30.0 50.5 58.7 82.1 34.6 39.4 63.0 33.3 47.8 56.1 63.3 36.3 56.6 44.8 45.6 32.0 64.8 62.2 59.9 61.0 7.5 42.7 44.1 40.7 58.4 32.9 52.8 40.8 56.7 85.2 61.5 56.2 54.8 102.0 38.7 66.3 25.6 25.5 53.1 43.3 59.0 78.6 42.0 57.5 40.4 16.5 9.3 18.9 11.4 12.1 15.2 11.9 13.4 12.8 10.9 8.0 14.3 12.7 8.1 17.8 14.6 5.2 13.4 11.1 26.4 26.2 28.0 39.2 25.5 26.0 26.1 27.1 26.4 28.3 26.1 27.7 64.3 25.6 42.8 81.9 118.7 123.9 70.2 64.6 86.0 92.3 68.1 50.0 70.6 61.5 58.4 58.8 20.9 161.2 108.2 39.0 68.4 77.7 65.6 54.3 64.2 75.5 57.2 100.4 68.0 54.1 176.6 70.1 37.8 57.0 62.1 64.6 63.9 50.6 67.0 62.2 70.1 52.7 73.2 63.7 96.7 75.5 126.2 73.5 67.6 85.3 137.2 104.3 232.8 92.0 113.4 59.6 40.2 127.2 80.2 110.0 49.9 88.0 47.6 78.8 78.9 64.2 78.8 194.9 151.6 75.4 131.6 137.4 101.5 69.2 51.4 71.7 LSM3 "SMX4, USS2, YLR438C" ENSG00000170860 "LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated" P62310 3 14178817-14201122 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 752.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044966 Approved Approved Nucleoplasm,Nucleoli NA NA 30000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoli Nucleoplasm "HPA044966: AB_2679159" "unprognostic (3.84e-3)" "unprognostic (7.00e-3)" "unprognostic (3.61e-2)" "unprognostic (2.87e-2)" "unprognostic (2.27e-1)" "unprognostic (2.19e-1)" "unprognostic (2.94e-3)" "unprognostic (5.01e-2)" "unprognostic (2.70e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-2)" "unprognostic (8.07e-3)" "unprognostic (4.93e-3)" "unprognostic (5.57e-2)" "unprognostic (2.88e-1)" "unprognostic (1.46e-1)" "unprognostic (1.89e-3)" 12.6 10.8 12.1 11.0 12.6 18.9 12.6 13.2 16.6 8.7 12.1 12.1 12.4 9.1 10.4 12.1 8.2 6.5 17.4 12.6 12.7 23.3 18.4 8.2 12.9 12.3 12.0 9.4 9.5 11.0 9.0 10.3 12.5 9.8 11.2 10.7 9.2 8.3 30.1 10.1 12.9 8.1 12.4 9.7 10.5 12.3 12.6 16.8 10.7 22.4 11.8 10.3 8.7 13.2 36.0 28.6 30.1 31.3 13.8 16.0 76.3 29.0 19.3 36.6 34.8 32.6 27.6 39.5 23.5 20.3 25.7 16.4 34.5 28.4 36.0 37.5 42.3 41.8 38.1 31.5 7.1 47.3 29.0 12.0 20.2 36.8 15.6 16.4 19.1 34.0 45.9 30.7 27.4 41.5 50.4 64.2 52.1 40.2 38.5 27.4 37.3 43.5 34.6 36.7 16.8 27.2 33.2 46.1 28.6 34.3 53.2 59.7 17.3 23.3 37.2 28.3 50.6 21.4 67.3 73.6 29.5 45.9 33.8 44.1 18.9 30.0 14.8 23.7 17.7 27.3 17.1 17.5 18.3 21.7 18.4 19.7 17.8 21.9 20.3 28.7 22.9 25.7 12.1 12.6 13.2 16.6 12.6 12.7 12.3 12.0 12.5 12.4 12.6 13.2 114.2 67.3 94.3 11.4 118.2 97.8 135.4 328.8 115.5 52.5 124.2 171.4 263.4 155.8 164.6 126.9 18.8 391.8 114.2 158.2 485.2 220.4 337.8 111.2 97.8 104.5 104.7 111.9 8.3 265.5 409.6 120.0 67.8 115.2 138.2 142.4 128.8 234.8 235.5 55.5 8.3 195.4 175.0 132.9 115.0 153.1 140.1 119.6 97.8 5.6 202.4 180.7 170.0 7.1 13.3 219.2 196.7 139.9 154.2 110.2 203.9 752.2 122.3 68.2 105.2 111.5 117.9 288.5 295.5 150.8 101.2 318.4 93.6 144.6 205.7 177.2 LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 705.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA040932: AB_10795529" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.42e-3)" "unprognostic (1.98e-1)" "unprognostic (4.09e-2)" "unprognostic (1.10e-3)" "unprognostic (9.80e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.34e-4)" "unprognostic (8.31e-3)" "unprognostic (1.25e-1)" "prognostic favorable (2.22e-4)" "unprognostic (2.51e-2)" "unprognostic (7.23e-2)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" 56.5 130.5 97.9 31.8 101.8 62.9 55.1 99.7 111.7 52.7 111.4 86.4 57.6 51.6 36.3 100.5 52.8 17.4 108.2 102.8 104.9 118.8 122.8 60.9 41.4 99.6 102.5 50.6 57.4 48.5 72.5 35.5 105.1 64.2 45.2 33.1 55.2 39.6 149.1 70.4 77.1 27.3 95.9 71.1 78.4 126.8 104.8 78.9 62.2 89.4 38.9 62.1 59.7 97.3 294.3 151.2 252.3 226.2 95.4 91.4 291.8 132.2 113.6 167.9 158.7 137.0 305.5 172.0 274.5 139.0 152.5 192.3 276.4 274.5 127.1 201.1 524.0 156.1 247.0 167.5 94.9 148.9 89.2 83.3 160.5 156.9 182.9 94.2 139.6 248.6 333.0 172.3 177.3 479.7 411.0 321.6 327.1 419.2 475.4 229.4 112.0 320.5 212.9 102.0 283.8 264.9 113.0 141.3 204.2 174.8 140.4 157.8 81.0 98.0 113.2 244.3 250.5 160.2 147.7 204.4 131.4 289.3 170.4 171.5 223.2 163.8 148.3 258.5 182.5 163.5 158.3 154.4 252.8 164.5 169.7 171.4 18.4 220.4 205.6 359.0 166.9 283.9 97.9 101.8 99.7 111.7 102.8 104.9 99.6 102.5 105.1 95.9 104.8 97.3 76.8 28.9 38.8 7.5 85.1 67.4 92.4 183.1 46.7 72.0 141.7 134.9 53.2 74.4 90.5 115.8 14.6 270.4 95.8 179.1 299.3 196.7 280.8 102.8 55.1 75.7 124.4 109.8 11.5 182.1 489.1 67.9 68.8 96.9 117.4 115.7 54.3 89.3 288.4 58.9 11.1 194.5 154.6 85.4 129.0 705.7 62.4 109.1 104.9 7.5 243.2 115.6 130.7 7.1 13.4 159.3 205.5 47.4 98.3 153.1 225.3 347.7 94.6 73.0 46.0 38.5 80.7 203.1 378.6 125.5 71.9 170.5 87.7 174.2 237.1 119.9 LSM5 YER146W ENSG00000106355 "LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Y9 7 32485338-32495283 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019054 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA019054: AB_10960217" "unprognostic (1.92e-1)" "unprognostic (5.36e-2)" "unprognostic (3.23e-2)" "unprognostic (1.51e-1)" "unprognostic (8.92e-2)" "unprognostic (3.51e-2)" "prognostic unfavorable (7.53e-5)" "unprognostic (2.22e-1)" "unprognostic (1.77e-2)" "unprognostic (1.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.62e-1)" "prognostic unfavorable (1.84e-4)" "unprognostic (3.08e-1)" "unprognostic (3.89e-2)" "unprognostic (2.53e-2)" "unprognostic (1.18e-1)" 35.8 41.9 26.2 35.8 27.0 77.6 62.6 27.0 40.3 33.7 25.4 58.1 42.4 34.0 35.5 46.6 34.5 28.1 50.1 26.2 26.9 46.8 76.0 28.1 61.7 26.0 26.6 36.4 54.7 30.0 29.1 28.8 26.5 34.3 60.0 28.8 31.4 27.8 57.6 33.8 39.4 36.5 26.7 41.0 47.0 22.5 26.3 67.9 44.4 51.1 72.2 37.6 34.4 27.0 204.6 121.9 162.8 229.4 56.0 62.2 80.9 94.9 79.9 119.3 125.6 168.9 170.0 118.8 49.0 67.7 290.9 119.1 121.1 118.7 161.2 84.6 132.7 124.6 193.5 233.7 49.6 267.4 123.3 52.4 85.1 116.7 137.4 79.2 132.9 203.4 261.0 90.5 169.2 246.3 140.3 598.9 267.9 296.7 139.4 122.3 128.4 200.9 107.3 97.8 140.5 206.4 84.9 237.0 114.6 243.5 148.4 331.6 63.9 102.5 252.6 95.8 246.2 149.2 339.9 354.5 96.9 314.9 296.6 17.9 35.0 34.2 38.6 57.4 58.2 69.2 62.9 50.7 50.7 60.2 89.3 68.9 6.0 44.9 49.5 100.1 57.4 45.2 26.2 27.0 27.0 40.3 26.2 26.9 26.0 26.6 26.5 26.7 26.3 27.0 68.9 32.1 50.6 13.7 135.3 146.4 152.0 254.1 109.8 52.5 201.8 262.4 109.7 94.4 116.7 114.0 22.9 211.9 93.4 95.6 277.8 137.0 16.1 91.1 68.2 81.0 50.5 184.5 15.9 216.6 286.2 98.8 98.8 74.6 72.2 148.2 79.6 285.6 189.8 43.7 20.4 164.9 175.0 117.9 158.2 21.2 75.8 100.1 122.7 13.1 163.9 94.3 78.2 10.1 13.9 146.3 118.2 82.4 187.0 146.9 107.6 343.4 137.5 59.7 65.7 81.9 141.9 88.5 133.2 167.7 177.6 100.6 111.8 123.2 233.2 152.8 LYRM2 DJ122O8.2 ENSG00000083099 "LYR motif containing 2" Q9NU23 6 89568144-89638749 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063932 Uncertain Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA063932: AB_2685155" "unprognostic (3.23e-2)" "unprognostic (1.47e-1)" "unprognostic (8.52e-3)" "unprognostic (8.49e-2)" "unprognostic (4.27e-2)" "unprognostic (6.26e-2)" "prognostic unfavorable (2.58e-8)" "unprognostic (1.46e-1)" "unprognostic (1.18e-1)" "unprognostic (3.29e-3)" "unprognostic (8.07e-3)" "unprognostic (3.63e-2)" "unprognostic (7.98e-2)" "unprognostic (3.70e-1)" "unprognostic (1.45e-1)" "unprognostic (2.23e-2)" "unprognostic (5.64e-2)" 10.7 15.9 11.6 10.3 12.3 14.8 14.1 11.2 12.3 9.4 9.1 13.7 8.6 11.1 14.3 12.3 13.4 10.2 17.4 12.5 12.4 17.4 12.4 10.1 12.8 11.2 11.9 9.9 10.5 22.5 10.7 13.9 11.1 13.2 16.1 9.0 9.8 8.6 21.3 6.2 9.5 11.9 12.5 9.0 13.0 8.7 12.5 9.2 25.2 16.9 10.9 10.7 6.6 12.7 18.4 9.6 32.1 19.7 16.0 24.0 12.8 31.3 22.2 24.0 23.8 8.6 9.6 25.1 29.5 29.6 35.7 16.5 20.6 29.7 30.8 32.0 36.5 39.8 9.9 7.3 24.0 42.6 29.7 29.7 28.2 27.2 36.5 19.4 18.8 27.0 41.8 32.0 27.9 16.5 10.0 15.3 7.6 14.9 12.5 20.7 40.1 18.9 27.2 18.1 35.7 24.2 18.3 11.1 31.1 14.6 15.8 43.0 30.2 15.0 13.2 27.4 44.0 22.9 35.1 13.0 31.6 30.3 28.9 16.4 21.0 14.3 21.5 24.8 23.1 32.6 24.0 28.4 19.7 30.9 26.8 25.1 6.0 27.3 33.9 26.1 24.2 14.8 11.6 12.3 11.2 12.3 12.5 12.4 11.2 11.9 11.1 12.5 12.5 12.7 37.1 41.7 50.3 11.8 47.6 11.9 29.0 43.1 29.0 27.0 37.6 45.7 87.5 27.1 48.3 27.6 16.7 87.6 33.9 31.3 93.9 40.1 66.0 86.2 56.6 30.7 40.7 35.3 17.6 49.4 32.9 35.6 37.2 55.8 32.9 33.9 24.7 27.1 57.8 25.2 19.7 43.4 44.7 35.1 12.9 18.7 30.7 39.9 30.2 15.9 44.8 100.6 44.3 13.0 26.4 40.1 32.8 27.1 30.9 25.9 29.3 68.8 70.6 45.3 52.6 39.2 41.1 57.0 31.6 43.3 16.2 72.4 37.5 81.8 39.8 26.2 LZTFL1 BBS17 ENSG00000163818 "Leucine zipper transcription factor like 1" Q9NQ48 3 45823316-45916042 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 119.0;Endometrial ciliated cells: 56.7;Respiratory ciliated cells: 142.2;Spermatocytes: 170.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043466, HPA048447" Enhanced Supported Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA043466: AB_2678491, HPA048447: AB_2680398" "unprognostic (1.64e-2)" "unprognostic (1.34e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.65e-2)" "unprognostic (5.42e-2)" "unprognostic (1.15e-2)" "unprognostic (2.26e-2)" "unprognostic (4.20e-2)" "unprognostic (2.94e-2)" "unprognostic (7.83e-2)" "unprognostic (5.32e-2)" "unprognostic (1.30e-3)" "unprognostic (6.27e-3)" "unprognostic (8.31e-2)" "unprognostic (4.27e-3)" "unprognostic (4.19e-1)" 5.2 6.2 7.1 4.5 8.2 6.0 12.4 5.8 10.1 12.4 17.5 5.7 7.0 13.2 15.0 5.5 18.9 6.9 4.6 8.7 7.7 12.0 10.0 9.0 4.7 6.7 7.3 11.4 5.6 14.2 11.7 5.9 6.5 7.9 6.2 15.8 7.2 8.8 2.8 6.0 5.7 8.4 6.6 6.0 5.8 25.4 7.1 30.7 18.9 3.5 5.7 4.7 4.1 6.9 10.1 5.0 7.8 5.1 7.2 17.9 4.0 5.3 10.0 12.2 15.8 2.4 7.5 2.7 3.1 7.5 15.2 6.4 9.5 8.6 15.9 0.2 6.1 2.6 6.7 4.5 9.4 9.9 2.8 9.3 29.6 16.8 10.8 7.8 6.0 16.5 8.9 6.7 5.9 1.6 34.1 9.6 8.1 6.7 4.2 3.7 0.8 10.7 14.7 4.7 5.4 11.0 7.0 6.0 13.2 8.7 7.1 18.3 9.9 4.5 3.1 12.2 7.1 18.3 10.0 0.1 14.3 11.7 3.7 0.0 0.9 0.4 1.3 1.2 1.7 4.3 1.1 1.2 2.3 2.4 1.8 1.7 1.0 1.5 0.8 2.5 2.0 1.6 7.1 8.2 5.8 10.1 8.7 7.7 6.7 7.3 6.5 6.6 7.1 6.9 7.6 28.9 25.2 7.8 10.8 13.5 10.5 14.9 12.0 7.9 16.9 14.9 7.6 11.5 23.6 14.7 14.6 3.1 8.4 3.7 15.6 13.3 119.0 56.7 10.5 10.2 11.4 11.6 22.3 6.9 5.1 13.3 6.1 12.3 8.2 10.1 11.7 13.5 6.6 23.5 9.9 10.4 10.2 7.3 7.0 19.2 9.9 5.3 8.8 5.6 10.8 17.8 7.2 6.6 12.2 5.6 5.6 13.5 11.6 5.9 3.2 23.0 142.2 14.6 13.1 15.7 9.2 170.0 24.1 8.4 9.9 2.1 10.5 14.2 8.9 5.6 MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Fibroblasts: 1.7;Hofbauer cells: 4.9;Syncytiotrophoblasts: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 5 "dendritic cells: 12.6;monocytes: 5.4" "Cell line enhanced" "Detected in many" "AF22: 173.9;AN3-CA: 111.5;SCLC-21H: 137.0;SH-SY5Y: 132.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA035865: AB_10672099, HPA041189: AB_2677357" "unprognostic (1.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.46e-2)" "unprognostic (1.46e-2)" "unprognostic (7.71e-3)" "unprognostic (1.85e-1)" "unprognostic (3.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.67e-1)" "unprognostic (9.17e-2)" "unprognostic (7.32e-2)" "unprognostic (1.80e-2)" "unprognostic (1.31e-2)" "unprognostic (3.27e-2)" "unprognostic (4.58e-2)" "unprognostic (8.78e-2)" "unprognostic (4.66e-2)" 3.8 3.2 5.3 5.6 4.5 1.9 10.2 7.3 6.3 14.7 3.3 10.8 9.5 18.3 11.6 17.4 16.5 8.7 13.5 4.1 4.9 15.2 5.2 5.6 4.9 3.8 3.9 13.3 7.8 14.9 14.0 2.1 3.7 13.1 10.5 3.2 10.9 14.4 6.5 10.7 10.1 15.3 3.6 2.7 8.6 11.8 4.2 7.4 10.2 8.6 7.2 13.2 11.8 4.4 4.7 31.1 173.9 111.5 2.5 5.1 0.1 8.6 0.3 16.2 11.0 0.5 55.8 0.0 23.5 2.8 9.1 27.4 15.3 44.8 5.1 81.1 63.4 0.0 0.2 59.1 11.2 1.9 0.8 8.1 30.4 6.4 8.5 23.4 0.0 6.3 0.1 0.6 15.7 37.5 0.2 0.9 74.8 0.2 44.9 0.4 0.5 0.6 30.7 34.0 137.0 132.4 28.6 0.2 0.0 35.2 41.5 20.3 0.0 0.3 32.3 12.4 6.2 0.4 0.1 0.3 0.0 0.2 0.3 1.6 2.4 0.8 0.6 5.4 1.1 0.3 0.9 0.8 12.6 0.3 0.8 0.9 1.4 1.1 3.0 0.2 0.5 1.6 5.3 4.5 7.3 6.3 4.1 4.9 3.8 3.9 3.7 3.6 4.2 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 MAGED1 "DLXIN-1, NRAGE" ENSG00000179222 "MAGE family member D1" Q9Y5V3 X 51803007-51902354 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 335.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 534.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043645 Approved Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA043645: AB_2678597" "unprognostic (5.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.29e-2)" "unprognostic (1.39e-2)" "unprognostic (3.92e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-3)" "unprognostic (2.04e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-3)" "unprognostic (1.42e-1)" "unprognostic (6.10e-3)" "unprognostic (2.14e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (3.25e-4)" "unprognostic (1.71e-3)" 32.4 125.4 69.8 37.7 73.1 16.7 38.0 34.7 71.1 99.7 99.2 40.0 32.4 57.3 102.4 26.6 64.7 58.8 70.2 70.7 108.8 43.0 71.5 40.4 29.2 57.4 66.2 62.5 80.2 76.8 157.0 116.2 76.3 71.7 39.6 37.1 85.3 89.0 46.8 29.9 32.3 77.6 62.0 35.4 54.6 56.5 84.7 49.0 73.7 39.1 31.6 45.4 35.5 49.7 21.3 76.2 238.5 205.8 184.3 330.4 128.1 281.2 357.7 152.5 240.0 157.3 71.0 29.9 53.6 534.9 54.4 15.6 215.5 99.6 113.2 31.8 83.1 20.3 0.4 205.7 140.9 75.8 35.8 312.2 35.0 128.6 29.1 267.7 184.8 77.1 31.5 57.6 310.5 194.8 87.7 25.4 187.6 69.4 154.3 88.4 154.2 4.1 156.7 37.4 60.9 340.1 0.0 80.6 41.9 232.0 145.6 18.8 185.6 66.1 166.5 234.7 31.8 37.5 59.5 60.3 257.9 6.9 175.1 1.5 4.4 3.1 21.1 6.0 18.7 17.2 13.7 18.5 13.2 19.4 17.1 20.5 1.3 16.3 6.1 55.8 21.1 14.3 69.8 73.1 34.7 71.1 70.7 108.8 57.4 66.2 76.3 62.0 84.7 49.7 12.2 76.9 34.5 85.8 17.1 11.5 20.4 48.1 12.5 33.2 41.9 27.9 53.4 32.9 63.8 35.0 8.4 335.2 17.1 18.6 29.4 47.9 2.5 35.6 73.4 24.5 57.1 13.9 97.5 49.9 171.5 69.5 34.7 54.3 17.7 60.7 39.7 62.5 114.6 45.4 138.5 74.4 54.9 9.2 6.8 10.0 43.2 6.3 24.9 42.2 4.9 39.7 13.4 101.6 55.0 33.5 13.5 57.6 72.6 20.2 15.9 33.2 48.3 12.5 13.1 28.2 50.0 5.7 5.9 12.4 8.2 185.7 11.9 169.9 25.2 18.8 MAGEF1 ENSG00000177383 "MAGE family member F1" Q9HAY2 3 184710364-184712064 "Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046899, HPA054190" Uncertain Approved "Actin filaments" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Actin filaments" "HPA046899: AB_2679859, HPA054190: AB_2682411" "unprognostic (7.36e-3)" "unprognostic (3.79e-2)" "unprognostic (3.81e-2)" "unprognostic (1.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.46e-3)" "unprognostic (2.34e-3)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (2.80e-3)" "unprognostic (1.82e-1)" "unprognostic (8.51e-3)" "prognostic favorable (7.59e-4)" "unprognostic (7.65e-2)" "unprognostic (8.97e-2)" "unprognostic (3.15e-3)" "unprognostic (1.19e-1)" 16.8 26.9 28.9 16.4 29.3 2.7 24.0 29.6 33.4 33.7 31.3 28.2 17.4 32.4 35.9 20.7 26.1 15.5 26.2 29.1 37.7 36.3 25.4 20.3 21.3 29.0 29.8 27.4 29.3 35.5 56.3 23.1 29.2 30.3 17.1 27.0 25.9 26.8 32.6 22.7 20.3 19.1 29.7 19.1 27.0 12.3 31.8 21.7 29.7 21.7 17.6 27.3 21.7 27.9 86.3 22.3 89.8 56.1 32.0 12.9 61.8 32.1 34.9 53.2 53.3 54.8 31.3 59.1 65.2 29.2 88.1 60.0 46.2 27.7 49.0 96.2 65.1 17.3 32.9 77.4 31.5 27.4 27.4 29.7 34.4 33.9 10.7 25.4 13.0 19.3 30.3 40.0 31.5 108.8 10.4 60.8 56.9 54.6 38.4 29.9 72.6 18.4 39.5 56.4 99.0 94.6 49.5 83.1 77.4 50.0 132.4 10.1 9.1 35.0 61.6 41.1 62.9 82.9 65.6 78.7 27.6 9.8 46.3 0.1 1.4 2.5 1.6 0.3 0.6 2.8 2.2 1.8 5.7 4.7 6.1 3.1 0.2 1.2 0.2 0.4 2.3 0.9 28.9 29.3 29.6 33.4 29.1 37.7 29.0 29.8 29.2 29.7 31.8 27.9 6.5 32.1 25.8 10.4 22.1 18.7 52.7 56.9 30.1 60.3 37.5 33.7 19.2 48.6 33.0 42.3 10.4 103.2 6.0 9.2 146.8 54.3 1.2 27.0 22.3 16.0 49.3 13.2 14.6 41.3 56.4 37.3 27.5 19.0 5.7 36.1 20.3 26.2 68.6 63.9 15.1 46.1 71.2 8.1 36.3 3.9 55.3 10.1 24.9 6.5 32.3 67.3 20.6 13.6 12.6 30.0 22.4 57.2 26.5 44.3 11.2 64.8 30.1 49.2 32.9 30.7 33.4 21.3 8.9 29.6 13.8 60.5 11.4 56.8 32.5 72.3 MAGEH1 APR1 ENSG00000187601 "MAGE family member H1" Q9H213 X 55452127-55453566 "Predicted membrane proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "epididymis: 515.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011324, HPA011971" Uncertain Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Nucleoli rim" "HPA011324: AB_1853499, HPA011971: " "unprognostic (2.50e-1)" "unprognostic (3.01e-1)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (3.95e-2)" "unprognostic (8.50e-2)" "unprognostic (1.13e-2)" "unprognostic (9.93e-3)" "unprognostic (1.47e-1)" "unprognostic (3.20e-3)" "prognostic favorable (2.60e-4)" "unprognostic (6.37e-2)" "unprognostic (1.81e-2)" "unprognostic (1.29e-3)" "unprognostic (1.90e-1)" "unprognostic (3.95e-2)" "unprognostic (2.52e-1)" 20.2 29.9 46.8 17.6 48.2 5.1 18.4 40.9 59.3 29.6 59.4 21.0 10.2 30.9 515.9 10.0 45.3 18.1 24.1 47.1 60.0 25.5 19.6 23.5 22.7 41.9 47.7 36.3 28.1 25.5 54.1 20.9 45.7 48.8 11.5 22.0 18.6 44.3 12.9 11.3 17.1 27.3 45.5 20.4 25.3 33.8 50.3 32.0 28.6 16.9 17.0 17.9 16.7 48.8 0.1 5.7 32.6 0.0 51.5 31.0 0.4 36.0 32.9 9.7 26.0 0.1 7.4 0.0 48.2 36.4 18.4 4.9 12.5 13.5 15.2 42.5 2.0 11.4 0.0 4.6 17.0 0.6 14.1 25.8 1.2 5.6 4.1 9.1 15.0 12.0 6.5 43.8 10.8 22.0 30.8 9.8 9.3 0.0 6.8 19.1 4.1 24.0 17.9 0.0 0.2 24.5 0.0 9.5 15.5 24.4 4.7 8.5 17.7 13.3 15.4 8.2 1.9 25.9 35.1 4.9 24.8 15.8 17.2 14.0 9.0 20.5 21.5 14.3 19.4 18.9 35.4 24.6 13.7 17.9 48.2 30.5 1.2 18.9 18.5 28.5 52.1 19.0 46.8 48.2 40.9 59.3 47.1 60.0 41.9 47.7 45.7 45.5 50.3 48.8 24.9 6.4 14.4 4.9 18.3 8.0 7.8 20.0 5.2 36.7 8.0 14.1 10.4 18.6 12.5 12.9 10.4 2.8 15.7 1.9 13.7 32.2 1.6 2.8 33.5 29.0 15.8 3.0 14.2 10.7 2.0 42.9 3.1 1.9 12.7 11.1 32.9 14.0 15.0 37.0 17.5 8.4 4.1 3.8 11.2 4.0 47.2 6.2 21.4 6.5 9.3 56.8 23.7 18.6 28.4 4.7 8.8 63.9 39.8 13.7 0.8 20.1 6.7 19.6 26.3 44.5 35.0 1.4 2.7 3.3 6.3 1.6 19.9 19.7 4.6 4.8 MAGT1 "DKFZp564K142, IAP, MRX95, OST3B, SLC58A1" ENSG00000102158 "Magnesium transporter 1" Q9H0U3 X 77825747-77895593 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 145.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049851 Approved "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049851: AB_2680913" "prognostic unfavorable (1.30e-4)" "unprognostic (3.32e-1)" "unprognostic (6.47e-2)" "unprognostic (1.16e-1)" "unprognostic (2.39e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (8.98e-4)" "unprognostic (2.03e-2)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.03e-1)" "unprognostic (1.60e-2)" "unprognostic (5.56e-3)" "unprognostic (1.14e-1)" "unprognostic (6.25e-3)" "unprognostic (1.66e-1)" 25.3 22.6 12.9 24.2 19.4 20.8 36.5 17.2 17.4 39.4 14.4 28.3 25.7 27.5 53.7 25.6 25.9 25.1 37.5 13.0 16.4 41.9 71.2 26.8 22.5 20.9 18.5 23.6 31.9 38.4 18.5 36.4 21.9 33.5 27.0 5.2 34.6 28.0 17.1 18.3 26.2 24.3 16.6 23.5 29.4 11.3 17.9 21.0 78.0 21.9 23.5 29.1 18.2 27.0 62.5 34.1 41.7 48.8 75.0 49.3 64.8 66.9 67.4 51.7 56.5 45.6 99.5 45.6 90.9 71.7 53.3 56.4 88.4 50.8 80.0 32.3 55.4 30.6 46.2 42.5 66.6 64.9 31.1 45.3 43.5 64.6 56.7 55.1 74.0 31.2 36.5 123.2 64.7 40.4 36.2 23.9 56.1 64.6 41.3 43.3 72.5 84.7 61.9 45.8 14.1 26.3 91.6 64.8 58.0 43.6 43.8 35.3 75.2 45.6 51.1 71.7 33.2 44.8 103.1 58.1 49.7 60.5 61.0 15.3 12.9 13.7 17.2 19.7 18.4 12.5 15.6 16.6 11.1 10.7 14.9 17.7 11.0 18.6 21.0 22.2 12.8 15.7 12.9 19.4 17.2 17.4 13.0 16.4 20.9 18.5 21.9 16.6 17.9 27.0 50.2 41.7 53.6 9.8 37.3 33.0 55.3 51.6 24.5 5.2 39.1 25.1 53.4 42.9 51.6 40.5 4.2 33.3 43.4 44.8 3.9 35.3 2.2 23.7 38.9 40.7 22.7 33.0 6.1 34.9 59.3 43.7 33.1 58.0 30.4 24.5 43.2 145.6 42.3 1.7 6.3 39.6 32.6 49.8 46.1 2.5 30.7 45.1 33.8 15.9 33.9 17.1 18.6 13.6 28.0 36.2 37.2 27.1 87.4 65.4 31.2 32.0 20.7 5.2 19.7 38.7 31.2 6.6 16.7 36.5 45.6 81.3 36.0 31.2 26.0 69.4 MANBAL dJ1141E15.2 ENSG00000101363 "Mannosidase beta like" Q9NQG1 20 37289638-37317260 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052348 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria Nucleoplasm "HPA052348: AB_2681795" "unprognostic (1.86e-2)" "unprognostic (9.15e-2)" "unprognostic (1.85e-1)" "unprognostic (2.45e-2)" "unprognostic (3.12e-1)" "unprognostic (2.21e-3)" "prognostic unfavorable (7.07e-4)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (9.61e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "prognostic favorable (3.62e-4)" "unprognostic (1.06e-1)" "unprognostic (1.86e-1)" "unprognostic (8.03e-2)" "unprognostic (2.70e-2)" 51.5 70.5 68.6 23.4 68.2 7.3 51.6 67.3 76.3 67.5 68.8 92.7 35.0 86.1 57.1 64.4 71.6 30.6 43.5 70.0 71.3 57.8 42.0 40.5 16.7 69.4 68.8 66.9 45.5 49.8 57.5 33.2 70.2 77.4 40.1 28.0 45.9 61.8 24.4 58.3 48.7 65.4 68.4 34.2 60.3 42.7 71.9 22.6 55.1 17.9 25.4 81.2 58.5 68.3 66.0 126.5 63.0 63.9 101.0 73.1 54.5 89.9 93.1 85.1 66.6 150.3 87.4 16.9 104.8 109.8 86.7 88.5 60.3 140.2 57.9 12.7 62.5 17.8 51.3 135.3 109.0 19.1 10.8 80.1 97.8 79.3 130.1 85.4 60.2 22.1 29.1 18.1 86.2 77.3 24.0 25.1 50.4 109.6 117.0 14.4 82.7 19.9 81.6 90.3 60.4 68.9 91.1 135.1 76.3 53.7 91.1 30.2 66.6 155.5 58.1 88.6 70.3 24.0 34.9 14.0 111.8 10.4 82.3 12.3 22.8 33.2 14.9 27.0 17.0 24.3 17.9 18.0 21.0 25.6 21.4 20.9 33.8 21.1 21.4 29.2 12.8 16.7 68.6 68.2 67.3 76.3 70.0 71.3 69.4 68.8 70.2 68.4 71.9 68.3 19.9 25.6 27.1 10.1 9.5 30.1 87.3 84.2 33.0 22.7 41.3 47.9 19.6 35.8 42.1 44.1 4.2 97.0 9.1 24.7 39.2 74.5 6.6 23.8 26.6 28.5 30.5 2.1 8.6 109.3 133.4 42.6 23.9 20.4 7.6 31.5 28.9 22.5 30.3 20.2 10.7 36.7 50.8 15.1 20.6 8.0 46.9 12.3 46.2 6.5 18.0 71.4 18.6 13.0 8.4 103.2 48.4 68.4 16.8 96.0 40.9 61.1 29.9 15.4 19.7 27.4 38.7 26.4 43.8 36.5 30.4 76.9 8.4 40.7 34.8 124.7 MAP7 E-MAP-115 ENSG00000135525 "Microtubule associated protein 7" Q14244 6 136342281-136550819 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1501.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 4 "dendritic cells: 5.7;granulocytes: 12.2;monocytes: 3.1" "Cell line enhanced" "Detected in many" "CACO-2: 59.8;HeLa: 69.2;MCF7: 88.5;OE19: 55.3;RT4: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029712, HPA029713" Enhanced Supported Microtubules,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 45: Intestine - Brush border" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Microtubules "HPA029712: AB_10600303, HPA029713: AB_10601339" "unprognostic (8.68e-3)" "prognostic unfavorable (9.70e-5)" "unprognostic (2.33e-3)" "unprognostic (4.35e-3)" "unprognostic (6.95e-2)" "unprognostic (3.35e-1)" "prognostic favorable (9.22e-4)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.72e-1)" "unprognostic (4.61e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.07e-7)" "unprognostic (1.62e-3)" "unprognostic (7.84e-2)" "unprognostic (3.62e-1)" "unprognostic (6.51e-2)" 2.7 8.4 36.6 4.9 81.2 4.8 13.1 53.0 49.8 6.1 0.6 24.6 29.0 2.4 19.5 15.8 10.0 8.2 1.4 40.2 59.8 32.6 17.2 7.0 1.5 78.0 67.2 1.5 25.1 24.9 12.0 6.8 75.8 20.0 23.2 57.3 20.3 6.4 0.8 17.1 26.6 2.4 43.3 1.8 18.7 27.4 63.0 5.1 16.1 0.2 5.1 12.0 9.6 130.4 25.6 39.2 0.3 0.1 0.2 0.2 40.4 0.7 1.2 0.4 0.7 59.8 26.3 0.1 5.3 0.8 6.7 38.2 11.1 34.6 0.7 0.2 24.6 26.6 69.2 0.5 0.3 26.1 3.0 0.1 31.5 0.2 2.4 1.0 0.2 2.0 18.4 0.6 0.1 88.5 0.2 2.6 5.2 55.3 5.7 0.1 1.0 4.8 23.6 68.4 24.4 5.2 27.4 51.7 0.6 9.1 20.5 2.6 0.5 0.1 1.9 0.4 1.7 4.6 6.4 0.2 0.5 10.1 0.7 2.8 2.3 0.0 0.0 1.6 0.3 1.4 0.5 0.0 5.7 1.6 0.1 0.0 12.2 0.7 3.1 0.0 0.2 0.7 36.6 81.2 53.0 49.8 40.2 59.8 78.0 67.2 75.8 43.3 63.0 130.4 4.0 57.7 51.4 117.2 1.9 28.2 48.7 21.7 33.6 367.0 29.5 18.4 3.0 28.6 42.9 18.4 146.0 33.1 0.7 67.9 31.3 35.8 293.9 30.4 5.9 4.9 117.7 35.1 217.1 49.0 23.1 4.4 42.8 60.8 0.0 1.2 0.7 37.0 16.3 304.5 258.6 81.5 22.4 3.2 8.5 53.1 6.8 6.2 17.8 15.0 3.2 50.9 0.0 26.2 1501.2 37.2 51.9 3.4 4.4 56.6 60.7 81.8 56.0 104.7 19.7 2.0 5.2 37.5 23.4 49.0 30.4 76.2 3.4 2.8 64.2 62.8 MAP9 "ASAP, FLJ21159" ENSG00000164114 "Microtubule associated protein 9" Q49MG5 4 155342658-155376970 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.3;parathyroid gland: 33.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 114.4;Respiratory ciliated cells: 125.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (8.00e-2)" "unprognostic (1.60e-1)" "unprognostic (6.53e-2)" "unprognostic (6.11e-2)" "unprognostic (2.11e-1)" "unprognostic (5.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.01e-1)" "unprognostic (7.58e-2)" "unprognostic (2.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-1)" "unprognostic (4.39e-2)" "unprognostic (2.48e-2)" "unprognostic (1.04e-1)" "unprognostic (4.05e-2)" "unprognostic (9.54e-2)" 4.2 5.8 20.5 3.9 21.4 1.8 4.4 26.4 46.3 5.8 26.2 3.1 0.9 7.3 7.6 2.9 9.6 7.9 7.0 23.5 35.1 9.7 0.7 5.0 3.2 31.6 23.9 6.0 5.5 33.9 7.8 5.1 31.3 12.4 1.8 16.3 2.4 8.9 0.2 0.5 1.6 5.7 20.9 2.4 6.1 12.8 28.7 3.4 15.5 0.8 2.4 3.2 1.6 22.1 0.0 10.3 11.0 9.6 11.7 14.0 2.2 11.3 10.2 6.6 5.7 0.1 0.0 7.5 14.7 8.3 24.6 0.0 11.7 12.0 10.8 0.0 9.4 4.7 0.1 0.0 8.6 0.0 0.0 12.0 6.5 9.3 5.7 20.2 0.0 2.9 0.1 0.0 7.5 4.6 8.8 0.1 8.7 3.7 13.3 0.0 0.0 0.2 22.2 8.9 15.1 43.4 0.0 19.4 0.6 7.3 15.7 0.1 1.6 8.8 15.6 0.2 8.4 9.1 0.0 8.2 25.8 0.0 14.3 0.0 0.0 0.0 2.7 0.3 2.1 2.9 1.5 2.5 0.1 4.8 1.3 1.8 0.1 0.8 0.0 2.6 1.0 0.5 20.5 21.4 26.4 46.3 23.5 35.1 31.6 23.9 31.3 20.9 28.7 22.1 3.8 16.0 37.4 34.6 17.0 1.3 13.4 18.7 12.5 67.0 15.2 20.8 33.1 17.2 25.7 25.8 79.2 9.0 10.2 0.4 33.2 35.4 39.3 114.4 44.8 3.5 21.1 5.0 59.0 16.0 3.4 24.5 13.7 24.7 2.5 16.5 1.8 0.6 1.0 72.3 58.3 0.7 26.4 0.9 0.8 14.1 45.7 2.0 5.4 14.0 1.3 53.5 9.2 23.6 27.4 15.9 0.2 49.2 3.8 11.7 0.0 49.1 125.0 92.5 13.1 28.0 31.1 69.4 53.1 2.8 1.1 2.3 14.2 40.1 0.6 4.1 MAPRE1 EB1 ENSG00000101367 "Microtubule associated protein RP/EB family member 1" Q15691 20 32819954-32850405 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003600, CAB009337, CAB019391" Supported Enhanced "Centriolar satellite,Cytosol" NA NA 11000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Centriolar satellite, Cytosol" "CAB009337: AB_2141629, CAB019391: , HPA003600: AB_1079309" "unprognostic (3.74e-1)" "unprognostic (1.89e-1)" "unprognostic (2.68e-1)" "unprognostic (4.48e-3)" "unprognostic (2.98e-3)" "unprognostic (1.10e-2)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.25e-2)" "unprognostic (1.17e-1)" "unprognostic (7.24e-2)" "unprognostic (5.99e-2)" "unprognostic (6.05e-2)" "unprognostic (3.76e-2)" "unprognostic (3.07e-2)" "unprognostic (1.03e-1)" "unprognostic (5.42e-2)" "unprognostic (4.59e-3)" 66.7 44.5 41.2 69.7 46.7 192.7 48.3 45.3 45.5 45.9 41.9 69.0 39.7 61.0 52.9 62.7 44.8 57.4 58.2 37.0 50.0 54.1 30.4 50.6 75.8 48.0 52.5 37.8 40.4 38.3 24.3 66.8 47.9 56.0 58.0 16.1 32.7 70.6 34.1 34.7 41.2 91.3 47.7 57.7 43.9 54.4 47.5 88.0 74.1 39.7 69.3 83.1 37.8 47.0 179.7 161.4 176.6 102.0 93.5 84.3 250.7 171.3 106.3 261.0 191.0 470.0 161.9 271.2 167.4 154.8 265.6 159.9 213.1 191.6 283.7 92.4 83.1 523.3 105.0 253.2 98.7 190.6 222.8 91.6 94.1 213.8 141.7 89.3 165.0 151.4 240.0 150.6 232.4 111.0 263.0 166.2 127.6 182.7 147.5 174.4 312.8 145.9 143.0 121.8 109.7 115.3 307.2 134.3 179.4 160.6 194.3 140.0 147.5 291.9 157.7 147.3 224.7 131.5 194.5 289.6 154.9 428.3 166.0 256.8 125.8 262.1 100.1 150.8 104.0 75.1 94.1 92.9 97.4 81.8 94.6 104.3 139.7 111.1 170.6 89.5 107.1 185.6 41.2 46.7 45.3 45.5 37.0 50.0 48.0 52.5 47.9 47.7 47.5 47.0 71.6 19.2 30.2 8.1 67.0 132.8 194.4 48.1 62.0 11.1 54.7 42.3 36.5 25.8 44.5 55.2 8.4 108.0 82.0 67.6 84.1 68.8 90.2 43.5 44.7 64.8 71.5 52.8 7.8 78.3 130.0 61.4 40.8 60.9 115.4 45.7 39.3 14.9 107.0 10.1 8.5 43.6 36.7 94.6 121.2 76.6 35.8 99.5 71.2 12.2 120.5 36.5 92.7 7.5 12.6 75.0 40.5 64.3 71.1 115.3 32.6 74.3 39.4 11.5 65.7 61.5 102.8 72.1 62.1 65.2 110.8 169.2 89.8 76.6 44.4 123.1 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MAT2A "MATA2, MATII, SAMS2" ENSG00000168906 "Methionine adenosyltransferase 2A" P31153 2 85539168-85545281 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 874.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009968, HPA043028" Approved Approved Nucleoplasm,Cytosol NA NA 1800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB009968: AB_675710, HPA043028: AB_10960707" "unprognostic (1.38e-3)" "unprognostic (2.58e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (5.29e-5)" "unprognostic (9.89e-3)" "unprognostic (5.90e-3)" "prognostic unfavorable (4.87e-4)" "prognostic favorable (8.94e-4)" "prognostic unfavorable (5.94e-5)" "unprognostic (4.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.59e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-2)" 270.4 277.5 184.1 153.2 226.7 98.3 136.1 199.3 235.9 173.0 152.6 193.2 141.4 165.5 236.0 166.2 200.1 209.5 189.6 191.5 207.3 203.6 115.7 168.5 121.8 226.8 219.3 211.0 874.7 165.8 284.1 122.3 208.0 196.2 146.5 248.7 137.7 120.0 278.9 141.1 155.6 127.2 194.4 116.7 225.5 132.3 219.2 102.1 388.8 112.0 127.7 262.9 168.2 289.7 175.3 253.0 290.4 181.6 195.3 236.7 171.1 213.5 195.6 219.3 232.4 208.4 569.9 404.5 137.0 261.0 178.9 264.3 369.6 318.6 279.8 207.0 271.0 242.5 408.7 181.9 355.6 364.3 259.7 215.9 315.8 237.4 164.1 278.1 211.5 230.7 277.9 309.0 505.1 149.5 334.4 398.2 193.5 148.7 320.8 350.3 275.0 264.2 328.9 271.2 227.9 209.6 193.2 183.4 354.6 145.9 156.0 192.3 207.7 267.4 160.9 149.3 260.5 189.0 161.4 290.6 175.0 447.3 143.8 9.1 24.7 8.2 22.3 26.9 32.7 19.8 25.2 23.7 23.6 18.9 23.1 20.5 2.5 27.3 22.3 16.6 24.2 24.9 184.1 226.7 199.3 235.9 191.5 207.3 226.8 219.3 208.0 194.4 219.2 289.7 150.5 48.1 83.6 122.4 104.2 143.5 217.1 47.1 206.1 73.5 116.3 134.6 6.5 82.9 57.6 71.7 68.8 36.2 126.3 60.6 19.6 59.2 75.2 28.8 49.2 83.6 83.3 87.1 56.1 58.5 40.6 121.9 106.0 47.4 84.4 83.3 45.0 44.6 67.4 26.9 60.4 65.1 26.4 118.8 141.9 25.8 72.1 165.7 67.6 26.2 64.6 58.8 27.8 28.6 95.5 53.6 48.0 83.8 78.4 66.7 73.8 138.7 35.2 89.0 111.7 298.5 231.0 54.1 56.2 168.2 118.3 38.2 102.0 51.1 70.6 88.4 MAT2B "MATIIbeta, SDR23E1" ENSG00000038274 "Methionine adenosyltransferase 2B" Q9NZL9 5 163503114-163519354 "Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037721, HPA037722" Uncertain Approved "Plasma membrane" NA NA 1100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA037721: AB_10672389, HPA037722: AB_10671718" "unprognostic (1.22e-2)" "unprognostic (2.80e-2)" "unprognostic (1.80e-3)" "unprognostic (1.64e-1)" "unprognostic (5.06e-1)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (9.72e-2)" "unprognostic (1.68e-1)" "unprognostic (5.19e-3)" "unprognostic (3.57e-2)" "prognostic favorable (4.51e-7)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-3)" 36.6 54.6 31.1 64.7 32.4 31.1 50.5 35.3 39.8 46.9 37.5 61.5 86.9 45.4 59.4 40.9 66.7 42.1 75.3 32.8 33.7 104.8 82.7 56.1 102.6 32.2 35.3 73.3 23.9 69.2 22.0 48.9 33.3 46.1 66.5 47.8 64.3 53.2 57.8 34.6 84.4 44.4 34.6 84.5 57.2 31.7 33.3 89.6 81.4 63.7 92.7 60.9 33.2 34.0 72.4 60.0 100.6 55.1 73.4 72.9 62.2 61.8 68.5 67.7 99.4 41.5 128.5 74.8 127.6 66.0 99.5 56.6 84.8 125.4 89.1 254.5 69.6 67.3 63.3 62.1 95.9 71.0 44.7 60.4 101.1 86.1 66.4 81.8 149.5 76.6 54.8 90.8 84.0 40.7 99.2 85.9 38.6 43.9 40.0 112.4 49.2 123.4 111.7 76.6 40.4 57.9 82.8 58.2 93.8 44.1 76.5 95.1 121.2 73.6 48.5 51.8 107.7 78.4 82.3 68.3 54.1 129.1 51.3 619.4 227.5 477.4 321.5 274.3 355.8 359.1 351.2 349.3 204.6 345.3 352.7 341.4 357.8 401.5 302.4 167.2 528.3 689.9 31.1 32.4 35.3 39.8 32.8 33.7 32.2 35.3 33.3 34.6 33.3 34.0 24.9 48.1 43.3 8.8 90.1 42.7 35.1 75.6 129.1 23.2 26.0 20.7 57.7 41.5 48.1 44.1 8.4 61.3 62.8 49.2 62.6 38.8 39.0 63.5 36.2 38.9 15.0 79.3 15.0 26.2 29.7 34.6 36.2 44.2 28.4 28.1 35.7 58.3 45.3 18.5 12.8 40.8 61.1 83.3 55.3 13.3 34.5 48.5 42.7 18.7 70.6 41.7 80.3 9.0 16.2 28.9 38.1 31.2 65.7 46.8 53.4 103.7 72.6 17.6 46.0 21.7 35.6 23.6 30.5 69.8 36.2 37.6 84.2 23.3 51.3 45.7 MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.5;brain: 41.9" "Cell type enhanced" "Detected in many" "dendritic cells: 177.0;Hofbauer cells: 57.4;NK-cells: 422.2;T-cells: 99.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 76.8" "Group enriched" "Detected in many" 57 "NK-cells: 76.8;T-cells: 46.2" "Cell line enhanced" "Detected in some" "HL-60: 108.3;HMC-1: 30.9;K-562: 48.9;MCF7: 34.4;NB-4: 74.8;SCLC-21H: 30.9;THP-1: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: AB_1079316, HPA066547: " "prognostic favorable (5.27e-4)" "unprognostic (1.28e-2)" "unprognostic (1.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.36e-1)" "unprognostic (3.39e-2)" "unprognostic (9.50e-2)" "unprognostic (1.23e-1)" "unprognostic (7.91e-2)" "unprognostic (3.19e-3)" "unprognostic (2.07e-2)" "unprognostic (4.51e-2)" "unprognostic (1.16e-2)" "unprognostic (7.59e-2)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.33e-2)" 4.7 1.3 18.3 6.6 21.3 20.5 2.5 2.9 41.9 1.1 1.6 2.1 6.6 0.9 0.1 2.1 4.0 4.4 1.4 25.9 8.7 2.4 3.2 9.9 9.4 10.4 11.0 0.7 1.2 0.7 2.7 1.0 8.8 1.3 1.1 2.2 3.2 0.7 0.8 1.9 6.2 0.8 4.7 16.5 4.0 3.1 14.1 3.8 1.6 0.2 4.0 1.6 1.1 23.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.7 0.0 1.0 10.6 13.8 0.4 0.0 0.0 18.1 12.0 1.5 2.9 0.0 108.3 30.9 0.1 0.0 0.2 0.1 0.0 0.0 1.2 48.9 0.1 0.0 34.4 0.3 74.8 8.4 9.0 0.3 0.0 0.1 0.0 0.0 0.0 30.9 0.1 0.1 0.1 0.1 0.9 0.0 27.4 3.3 0.0 0.6 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 46.2 0.0 31.3 0.0 5.7 29.3 0.8 0.9 2.7 16.4 1.0 76.8 0.2 0.3 0.4 7.6 18.3 21.3 2.9 41.9 25.9 8.7 10.4 11.0 8.8 4.7 14.1 23.6 1.4 0.0 1.1 0.3 11.1 0.4 0.1 0.0 0.0 1.4 4.9 7.2 1.3 0.0 0.0 0.0 12.5 0.3 177.0 0.3 0.0 0.0 2.0 0.2 0.5 1.9 7.1 28.6 17.7 0.0 0.5 0.8 11.7 0.5 44.5 0.1 8.6 1.1 57.4 0.0 8.3 0.3 0.0 6.0 14.6 5.1 0.0 11.5 1.8 4.7 3.0 1.3 422.2 2.0 1.6 0.0 1.1 0.0 17.1 0.1 0.3 0.2 0.7 2.0 0.0 0.5 1.2 0.4 4.5 1.3 1.1 0.3 99.7 0.0 1.1 0.0 MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" NA NA 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" 52.0 155.5 41.3 35.6 43.1 34.7 55.1 38.1 40.3 50.4 69.5 32.2 32.5 54.5 42.1 45.9 41.9 44.9 42.3 41.3 46.8 59.4 111.8 45.0 32.1 33.5 41.3 79.2 104.1 52.5 38.7 70.1 41.6 54.0 26.9 83.3 149.7 82.9 83.3 26.0 33.4 52.5 28.0 44.6 33.9 30.9 48.6 30.8 121.0 84.6 34.2 41.2 29.2 34.7 147.7 86.9 74.7 59.7 151.5 215.1 115.4 248.4 254.1 129.4 116.8 116.9 109.4 96.4 297.7 294.7 154.3 81.8 67.0 127.0 207.7 64.5 67.2 101.9 87.1 182.5 236.5 94.8 158.6 163.2 77.8 206.7 178.7 247.9 210.8 28.0 199.3 56.0 266.8 48.7 56.9 67.6 63.9 102.3 84.1 68.3 133.2 106.7 80.3 59.3 23.9 62.2 93.1 46.9 116.0 86.3 33.1 80.6 341.1 298.3 130.5 97.0 164.2 42.0 43.8 76.4 320.2 88.0 100.8 27.2 21.4 29.7 9.6 23.3 12.2 12.5 10.9 10.2 18.4 12.8 14.3 9.8 12.0 9.9 18.3 16.9 9.7 14.0 41.3 43.1 38.1 40.3 41.3 46.8 33.5 41.3 41.6 28.0 48.6 34.7 50.8 105.8 89.1 16.6 29.6 48.2 56.5 65.3 36.5 69.3 64.4 48.5 70.3 38.6 68.8 47.8 39.6 75.5 25.4 26.6 21.5 88.6 144.3 76.4 60.2 64.7 26.8 28.2 19.6 178.5 64.5 70.1 20.4 69.9 50.5 44.1 53.9 155.1 54.5 38.7 23.8 28.5 18.3 40.5 31.3 113.7 62.7 39.2 12.4 7.5 33.8 253.2 12.3 16.1 16.2 152.7 23.1 59.5 43.8 82.4 42.2 41.3 69.6 51.3 65.7 63.9 55.4 48.9 32.6 39.6 44.9 102.1 23.4 74.3 22.8 75.8 MCUR1 "C6orf79, CCDC90A, FLJ20958" ENSG00000050393 "Mitochondrial calcium uniporter regulator 1" Q96AQ8 6 13786557-13814568 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 81.6" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 238.5;Rod photoreceptor cells: 293.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078654 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA078654: " "unprognostic (1.82e-3)" "unprognostic (1.58e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-3)" "unprognostic (8.62e-2)" "unprognostic (2.25e-3)" "unprognostic (2.01e-3)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "prognostic favorable (5.51e-4)" "unprognostic (3.40e-1)" "unprognostic (5.77e-2)" "prognostic favorable (3.32e-4)" "unprognostic (5.86e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-2)" "unprognostic (2.39e-1)" 9.7 5.4 20.2 7.2 21.0 7.1 10.0 19.6 32.6 7.8 18.5 10.8 19.1 7.0 13.1 10.0 4.6 5.5 12.2 20.9 21.3 22.6 9.2 8.6 6.6 21.0 20.8 3.9 12.6 9.0 5.9 8.7 22.0 6.4 9.7 81.6 9.1 7.6 19.3 18.3 16.5 5.1 20.0 7.6 6.4 4.8 22.5 8.1 16.0 15.8 9.4 6.2 7.7 19.7 23.4 6.9 34.4 34.6 19.8 17.0 21.8 21.0 19.9 22.4 23.4 24.0 11.3 31.6 41.0 15.1 35.2 10.2 21.5 17.7 25.4 21.2 13.1 32.3 12.2 24.0 19.4 32.4 12.6 11.9 16.9 29.1 20.9 16.7 8.1 38.7 24.4 16.3 15.8 9.7 40.1 49.0 22.2 59.9 9.0 29.2 30.3 45.2 27.4 14.2 22.0 24.9 14.0 35.4 58.1 53.1 13.2 14.6 11.5 33.5 18.8 24.2 29.3 20.0 71.9 45.4 15.6 19.0 46.4 4.2 1.3 0.3 1.5 1.2 1.8 1.9 2.1 2.2 3.2 1.7 1.6 1.5 0.8 1.7 1.7 2.0 1.3 2.9 20.2 21.0 19.6 32.6 20.9 21.3 21.0 20.8 22.0 20.0 22.5 19.7 40.5 16.0 25.0 13.1 33.2 44.7 24.2 16.9 39.3 48.0 62.8 54.1 43.6 28.6 15.1 57.0 120.9 45.3 27.2 75.0 138.9 27.4 48.9 29.3 83.5 38.7 15.6 62.9 16.7 31.7 66.9 30.5 7.1 31.3 7.0 16.7 28.2 72.4 91.6 26.9 11.5 49.6 24.4 34.7 80.2 6.8 22.1 60.1 51.6 10.3 36.6 50.4 25.7 7.5 13.4 29.2 91.3 27.1 80.7 60.2 161.6 238.5 11.2 293.7 19.7 20.7 34.5 13.1 52.4 47.3 57.4 86.2 21.0 31.0 37.5 31.1 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 MED20 "DKFZp586D2223, PRO0213, SRB2, TRFP" ENSG00000124641 "Mediator complex subunit 20" Q9H944 6 41905354-41921139 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 24.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040717 Uncertain Approved Nucleoplasm,Centrosome NA NA "Cluster 24: B-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Centrosome Nucleoplasm "HPA040717: AB_10794146" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (2.58e-3)" "unprognostic (8.32e-2)" "unprognostic (9.86e-3)" "unprognostic (1.72e-1)" "unprognostic (1.16e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (1.58e-3)" "unprognostic (4.23e-2)" "unprognostic (5.10e-2)" "prognostic favorable (1.17e-4)" "unprognostic (1.71e-2)" "unprognostic (4.63e-1)" "unprognostic (4.13e-3)" "unprognostic (2.31e-1)" 8.1 11.8 6.3 7.7 7.3 6.1 10.9 9.1 8.0 10.6 7.9 10.6 10.5 9.7 13.5 9.8 9.9 7.7 11.6 6.5 7.1 12.8 10.4 7.4 10.0 6.6 6.6 8.2 9.3 10.6 6.4 13.6 7.0 11.2 11.8 5.9 8.7 10.2 14.5 9.7 8.7 12.0 5.8 9.2 9.7 7.4 7.2 12.7 11.9 16.6 13.3 10.2 7.6 9.0 28.5 23.0 25.7 32.1 23.1 24.8 31.7 18.2 17.1 25.9 20.5 29.5 20.3 41.4 34.3 23.0 15.5 22.0 39.7 26.4 31.2 22.2 14.7 37.5 19.6 28.6 23.9 30.5 22.2 18.6 36.8 22.5 33.3 19.6 33.9 36.4 49.0 19.3 32.7 25.7 36.3 22.3 35.1 93.5 19.3 48.0 29.4 15.1 34.9 19.9 23.7 18.6 25.3 12.6 26.5 28.7 24.7 32.4 33.2 18.2 38.9 11.4 22.5 19.3 27.1 85.7 9.9 33.3 26.3 18.7 24.9 18.4 10.7 29.4 14.0 19.0 7.3 12.2 26.1 23.6 9.4 11.3 9.3 17.4 20.7 23.5 14.4 16.7 6.3 7.3 9.1 8.0 6.5 7.1 6.6 6.6 7.0 5.8 7.2 9.0 4.4 9.6 3.9 2.3 6.6 3.7 4.2 7.2 6.8 2.4 7.0 5.1 5.2 2.8 6.8 7.3 0.0 22.7 7.3 6.6 7.9 6.9 0.6 5.1 7.1 4.2 9.6 8.0 2.8 3.3 18.6 5.0 6.1 6.7 7.0 8.3 8.6 8.3 8.7 1.7 2.8 5.6 14.2 6.3 2.6 0.7 3.4 3.7 1.8 4.7 6.3 3.7 7.2 5.5 3.0 4.9 3.1 6.8 5.7 4.7 5.8 10.1 4.6 4.2 0.0 3.6 4.9 8.3 13.6 5.8 5.7 24.9 3.0 7.1 7.2 5.4 MED29 "DKFZp434H247, IXL, MED2" ENSG00000063322 "Mediator complex subunit 29" Q9NX70 19 39391303-39400641 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055956 Supported Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055956: AB_2682986" "unprognostic (3.30e-2)" "unprognostic (3.51e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (2.68e-1)" "unprognostic (1.92e-1)" "unprognostic (2.85e-2)" "unprognostic (1.71e-1)" "unprognostic (5.36e-3)" "unprognostic (1.46e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-2)" "prognostic favorable (5.15e-5)" "unprognostic (9.51e-2)" "unprognostic (4.84e-2)" "unprognostic (2.17e-1)" "unprognostic (1.87e-2)" 18.8 28.6 38.3 16.0 39.5 18.1 19.0 37.5 39.5 22.6 27.9 23.1 17.2 23.2 21.4 16.3 28.7 17.1 24.1 37.8 37.0 21.8 27.9 17.4 19.1 39.6 39.2 31.9 24.0 42.0 27.9 15.6 37.7 23.1 13.1 18.3 23.1 22.8 38.0 17.7 17.4 18.5 37.2 19.7 20.2 16.5 42.1 18.6 29.9 14.1 16.7 20.7 17.5 38.9 28.3 73.2 21.7 22.3 31.0 23.5 17.3 29.9 31.9 27.1 21.8 36.2 26.6 20.9 38.9 27.7 23.7 14.5 20.3 25.4 16.1 40.8 37.3 26.9 28.8 24.6 25.2 25.8 22.7 25.0 20.3 28.5 31.5 29.3 21.8 39.4 18.1 25.3 27.9 36.7 25.3 7.7 16.6 34.5 25.4 41.3 29.8 29.6 26.3 47.0 33.3 30.1 60.8 39.4 26.6 13.1 30.8 27.9 25.2 22.9 23.8 29.0 30.4 32.5 40.3 35.2 32.3 19.2 37.7 48.2 48.3 41.2 38.3 59.7 38.2 46.5 35.7 35.2 36.9 43.0 42.4 40.6 54.2 40.0 77.5 30.0 46.8 47.0 38.3 39.5 37.5 39.5 37.8 37.0 39.6 39.2 37.7 37.2 42.1 38.9 33.6 28.9 41.1 8.8 36.5 22.2 30.2 31.9 25.6 24.9 45.0 57.9 36.5 25.8 30.1 31.3 12.5 36.6 34.9 53.3 52.8 28.0 49.8 46.6 40.6 30.4 32.8 27.8 8.1 28.4 31.4 36.3 126.9 46.7 43.7 28.0 37.5 43.4 40.7 23.5 10.1 40.2 40.7 40.3 72.5 71.6 38.5 46.9 28.4 8.4 38.1 37.5 26.8 5.5 13.5 25.5 60.2 32.4 47.8 17.6 86.8 62.3 37.1 15.9 52.6 33.3 52.5 34.8 16.4 29.3 20.3 28.9 40.1 27.9 32.7 17.9 MEFV "FMF, MEF, TRIM20" ENSG00000103313 "MEFV innate immuity regulator, pyrin" O15553 16 3242027-3256633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" Actin-binding "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 7.6;Kupffer cells: 15.1;Macrophages: 15.5;monocytes: 26.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "neutrophil: 8.3" "Group enriched" "Detected in many" 4 "granulocytes: 8.3;monocytes: 5.7" "Cell line enriched" "Detected in some" 6 "THP-1: 6.6" "Not detected" "Not detected" HPA077497 Supported Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA077497: " "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (4.96e-2)" "unprognostic (2.01e-1)" "unprognostic (2.49e-2)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.97e-2)" "unprognostic (1.09e-1)" "unprognostic (8.89e-2)" "unprognostic (3.27e-1)" "unprognostic (7.58e-7)" "unprognostic (1.08e-1)" "unprognostic (7.16e-4)" "unprognostic (1.73e-3)" "unprognostic (1.48e-1)" 2.4 0.6 0.1 6.5 0.2 6.1 0.3 0.4 1.0 0.2 0.3 0.4 0.5 0.2 0.2 0.3 0.6 1.0 0.5 0.3 0.1 0.4 0.7 4.0 0.4 0.3 0.2 0.1 0.2 0.0 0.2 0.8 0.5 0.2 0.3 0.2 0.3 0.0 0.7 0.2 0.6 1.0 0.0 8.9 0.4 1.3 0.3 0.4 0.3 0.3 0.3 1.8 0.3 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.2 1.1 0.0 2.4 3.2 0.1 0.0 3.4 0.0 0.1 0.1 0.0 1.7 0.2 0.0 0.1 8.3 0.3 5.7 0.1 0.0 1.2 0.1 0.2 0.4 1.0 0.3 0.1 0.3 0.2 0.5 0.0 0.3 0.4 0.2 0.0 1.3 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 7.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.4 0.2 1.0 0.0 0.1 0.0 0.0 15.1 2.4 0.3 0.0 15.5 0.0 0.0 26.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.3 0.7 0.0 0.1 0.0 0.6 0.0 0.0 0.1 MEGF9 EGFL5 ENSG00000106780 "Multiple EGF like domains 9" Q9H1U4 9 120600811-120714470 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 68.2" "Cell type enhanced" "Detected in many" "Astrocytes: 143.0;Cone photoreceptor cells: 212.7;Oligodendrocytes: 240.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 25.2" "Group enriched" "Detected in many" 5 "granulocytes: 25.2;monocytes: 7.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014319, HPA050238" Approved Approved Nucleoplasm,Cytosol NA NA 96000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Cytosol "HPA014319: AB_1848035, HPA050238: AB_2681060" "unprognostic (1.18e-1)" "unprognostic (5.33e-2)" "unprognostic (1.84e-1)" "unprognostic (1.75e-2)" "unprognostic (3.30e-1)" "unprognostic (3.68e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-2)" "unprognostic (3.63e-2)" "unprognostic (1.13e-2)" "unprognostic (5.92e-2)" "unprognostic (4.97e-2)" "prognostic favorable (5.48e-11)" "unprognostic (1.90e-2)" "unprognostic (1.50e-1)" "unprognostic (6.78e-2)" "unprognostic (1.41e-1)" 18.1 10.1 24.1 11.5 28.7 18.8 13.6 28.7 26.1 12.0 4.8 7.2 7.0 6.3 5.6 14.0 14.0 8.5 6.4 26.0 34.4 13.5 38.7 20.3 6.5 37.2 33.6 9.7 5.6 11.5 5.3 5.1 27.3 8.7 6.0 68.2 7.7 6.6 7.3 21.5 7.2 8.9 28.2 15.2 8.0 3.3 34.0 5.6 28.4 8.5 6.2 9.7 7.4 37.3 5.0 19.4 16.7 5.2 22.6 13.9 5.3 5.0 4.4 1.3 1.8 1.1 2.9 18.6 7.4 4.8 6.0 21.2 24.1 8.7 3.6 15.2 6.9 2.5 34.1 8.1 9.6 7.5 15.3 6.5 26.1 8.2 6.6 46.0 11.8 9.9 6.0 8.6 13.9 14.4 14.8 2.7 0.7 11.1 5.2 11.2 18.6 7.9 34.0 16.1 16.4 13.9 6.0 4.8 14.7 2.7 14.5 7.5 13.9 5.0 2.8 18.4 7.7 15.5 19.5 6.0 7.0 8.7 28.8 0.6 7.4 5.1 0.8 2.5 0.3 0.4 0.7 0.6 3.0 0.4 0.6 0.5 25.2 0.5 4.5 0.2 0.7 1.9 24.1 28.7 28.7 26.1 26.0 34.4 37.2 33.6 27.3 28.2 34.0 37.3 6.5 86.6 65.0 143.0 8.4 27.4 5.6 8.4 25.0 31.5 30.3 12.8 28.2 14.3 15.6 23.9 212.7 0.5 10.8 7.5 0.0 4.0 0.9 11.8 5.8 7.6 6.6 18.9 85.9 5.4 1.9 10.3 14.3 19.3 7.0 8.4 10.0 48.0 5.8 13.5 63.8 4.7 16.2 45.2 13.9 2.7 11.5 41.3 26.6 22.5 107.2 30.9 13.4 93.0 240.7 13.8 8.6 11.7 11.5 8.3 7.4 6.6 6.1 75.4 13.1 26.5 9.3 14.8 7.3 41.3 43.9 1.2 11.4 4.8 5.5 6.2 MEI4 ENSG00000269964 "Meiotic double-stranded break formation protein 4" A8MW99 6 77650274-77927028 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 4.0;testis: 3.7;thyroid gland: 2.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 86.1" "Cancer enhanced" "Detected in some" "renal cancer: 0.9;testis cancer: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 43: Testis - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.47e-1)" "unprognostic (9.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (1.88e-1)" "unprognostic (4.62e-2)" "unprognostic (9.70e-4)" "unprognostic (3.16e-1)" "unprognostic (2.86e-4)" "unprognostic (3.35e-2)" "unprognostic (4.17e-2)" "unprognostic (4.85e-2)" 0.1 0.7 0.4 0.0 0.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.2 0.6 4.0 0.8 0.0 0.0 1.0 0.5 0.0 2.0 0.1 1.0 0.0 1.2 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 3.7 0.6 0.0 2.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.2 0.2 0.6 1.0 0.5 1.2 0.5 0.6 0.6 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 86.1 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 21.3 0.3 0.0 0.0 9.4 0.0 0.6 0.0 2.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MELK KIAA0175 ENSG00000165304 "Maternal embryonic leucine zipper kinase" Q14680 9 36572862-36677683 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;lymphoid tissue: 21.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.1;Erythroid cells: 15.2;Extravillous trophoblasts: 44.1;Spermatocytes: 23.2;Spermatogonia: 21.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "T-reg: 1.7" "Lineage enriched" "Detected in single" 4 "T-cells: 1.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA017214 Uncertain NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 12: Non-specific - Cell cycle regulation" "HPA017214: AB_1853798" "unprognostic (5.03e-2)" "unprognostic (9.57e-2)" "unprognostic (2.27e-2)" "unprognostic (3.42e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.91e-7)" "prognostic unfavorable (3.99e-4)" "unprognostic (1.26e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (4.58e-4)" "unprognostic (4.69e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (8.86e-3)" "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (1.35e-1)" 0.9 0.5 0.0 5.7 0.0 10.0 1.4 0.0 0.1 1.3 0.0 6.8 5.2 1.0 0.0 7.9 0.3 0.6 0.2 0.0 0.0 0.3 0.7 0.9 10.0 0.0 0.1 0.2 0.3 0.1 0.0 5.3 0.1 0.3 8.5 0.0 1.2 0.1 0.0 3.4 4.4 2.4 0.0 2.0 3.2 9.2 0.3 21.0 0.3 0.1 11.7 1.7 2.3 0.0 123.4 62.1 81.6 48.5 11.1 18.8 47.1 88.8 62.2 121.5 148.2 47.8 47.3 40.9 27.8 43.8 106.5 41.0 71.7 55.5 133.1 112.3 28.6 32.0 69.1 48.1 4.3 50.2 39.0 6.9 9.8 93.9 53.0 15.6 62.2 61.9 41.7 63.2 100.9 40.9 63.1 23.4 65.1 55.1 47.9 57.4 54.9 25.8 37.7 40.7 55.1 40.8 47.4 45.3 28.6 45.2 38.0 23.7 30.8 65.4 81.8 56.1 82.3 12.3 47.9 60.7 41.2 36.8 91.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 1.9 4.6 0.9 3.5 0.0 0.0 0.9 0.8 0.4 0.0 2.0 0.0 0.0 16.1 0.7 4.5 0.0 1.1 2.8 2.9 1.4 1.3 0.0 15.2 0.8 1.1 44.1 3.3 4.6 2.1 0.0 7.8 1.4 0.7 10.1 0.0 0.7 4.7 4.1 1.6 3.0 2.7 1.2 1.9 0.0 0.0 3.1 0.0 2.1 1.0 0.4 1.7 2.7 0.0 10.2 0.5 0.6 0.1 2.0 0.0 0.0 0.0 3.7 23.2 21.3 9.3 1.7 8.9 2.7 0.7 8.9 2.3 MESD "BOCA, KIAA0081, MESDC2" ENSG00000117899 "Mesoderm development LRP chaperone" Q14696 15 80946289-80989828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" Chaperone "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 341.4;Extravillous trophoblasts: 279.3;Syncytiotrophoblasts: 436.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039414, HPA041721" Approved Supported "Nuclear bodies,Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "Nuclear bodies, Cytosol" "HPA039414: AB_10674981, HPA041721: AB_2756310" "unprognostic (9.21e-2)" "unprognostic (4.50e-2)" "unprognostic (8.02e-2)" "prognostic favorable (2.31e-4)" "unprognostic (4.93e-3)" "unprognostic (2.32e-3)" "unprognostic (3.47e-2)" "unprognostic (3.09e-3)" "unprognostic (4.04e-1)" "prognostic favorable (1.12e-4)" "unprognostic (7.93e-2)" "unprognostic (3.05e-2)" "unprognostic (3.42e-2)" "unprognostic (1.68e-1)" "unprognostic (4.32e-2)" "unprognostic (3.83e-1)" "unprognostic (1.88e-1)" 14.4 17.4 11.9 13.7 13.6 5.4 13.9 13.7 13.0 17.8 14.6 14.6 12.8 11.3 42.7 14.6 12.4 11.5 12.8 11.7 14.2 14.4 20.6 14.1 14.0 13.4 13.1 17.4 19.2 14.0 17.8 26.9 13.8 18.2 14.5 10.4 18.4 14.3 7.7 10.9 12.7 11.1 13.4 13.8 15.3 9.8 13.8 14.2 33.7 10.6 13.2 15.4 14.4 15.0 26.8 40.2 34.6 22.3 57.1 32.4 54.0 40.0 47.4 42.7 51.6 36.0 72.9 22.4 45.4 32.3 45.1 43.8 54.1 41.1 40.3 50.2 35.5 28.3 33.0 61.9 43.7 33.8 30.0 33.9 46.6 36.1 42.4 35.7 41.1 27.0 34.7 55.5 36.7 34.0 20.9 28.3 41.9 39.3 16.4 31.7 21.3 59.7 35.6 36.3 29.9 17.6 43.9 29.3 70.0 62.4 34.0 26.8 32.4 40.9 39.1 22.1 52.2 35.0 48.0 30.2 38.5 59.7 43.8 39.4 26.1 19.1 35.6 24.9 41.8 34.5 37.2 35.4 27.2 35.4 34.6 34.7 8.1 44.8 22.5 45.2 42.5 31.1 11.9 13.6 13.7 13.0 11.7 14.2 13.4 13.1 13.8 13.4 13.8 15.0 59.7 80.1 59.6 0.0 20.6 0.0 0.0 0.0 0.0 0.0 51.0 44.2 0.0 0.0 27.9 58.8 0.0 341.4 41.6 0.0 13.7 100.9 0.0 41.4 79.4 36.9 0.0 0.0 0.0 111.9 279.3 48.4 0.0 69.8 36.6 56.4 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.0 0.0 0.0 86.3 0.0 0.0 0.0 0.0 82.5 0.0 0.0 18.8 0.0 0.0 48.8 43.0 0.0 0.0 0.0 36.8 0.0 0.0 0.0 0.0 436.0 25.8 63.6 0.0 0.0 MFSD6L FLJ35773 ENSG00000185156 "Major facilitator superfamily domain containing 6 like" Q8IWD5 17 8797110-8799365 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 9.4;testis: 25.5" "Cell type enhanced" "Detected in some" "Early spermatids: 125.7;Ionocytes: 28.5;Late spermatids: 46.1;Spermatocytes: 45.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HMC-1: 8.3" "Not detected" "Not detected" HPA023164 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA023164: AB_2142777" "prognostic favorable (1.84e-4)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (3.64e-2)" "unprognostic (1.07e-4)" "unprognostic (3.31e-1)" "unprognostic (1.33e-1)" "unprognostic (2.32e-1)" "unprognostic (2.77e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" "unprognostic (7.26e-2)" "unprognostic (3.98e-3)" "unprognostic (1.33e-1)" "unprognostic (2.84e-1)" "unprognostic (7.68e-3)" "unprognostic (1.25e-1)" 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.0 0.1 1.8 0.0 2.7 2.3 0.1 1.3 0.6 2.0 0.7 0.2 0.0 0.0 1.6 0.0 0.3 0.0 0.1 0.1 0.0 9.4 4.1 4.9 0.4 0.1 0.4 3.1 0.0 6.8 2.1 0.0 0.3 1.5 0.0 0.0 0.2 4.0 25.5 0.2 0.2 3.4 0.0 0.2 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 1.7 0.8 0.2 4.3 1.1 1.8 0.0 2.9 0.0 1.7 0.0 7.2 125.7 1.2 0.1 0.1 1.2 0.0 0.0 7.6 0.3 0.0 3.6 2.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 5.9 28.5 0.6 0.0 46.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.7 1.2 0.1 0.8 0.2 0.0 0.8 0.0 0.0 0.0 0.2 45.0 0.3 0.6 0.0 1.5 0.0 0.0 4.5 1.0 MGAM MGA ENSG00000257335 Maltase-glucoamylase O43451 7 141907813-142106747 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 25.5;intestine: 87.6" "Group enriched" "Detected in some" 5 "Late spermatids: 156.4;Proximal enterocytes: 521.4" "Cancer enriched" "Detected in some" 7 "renal cancer: 4.9" "Region enhanced" "Detected in single" "cerebral cortex: 2.3" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.5" "Lineage enriched" "Detected in single" 102 "granulocytes: 13.5" "Cell line enhanced" "Detected in some" "A549: 1.8;BJ hTERT+: 1.6;HL-60: 2.8;U-937: 4.3;WM-115: 1.0" "Region enriched" "Detected in single" 12 "olfactory bulb: 2.0" "Low region specificity" "Detected in many" HPA002270 Enhanced NA NA 310000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 45: Enterocytes - Digestion" "HPA002270: AB_1079366" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (6.95e-3)" "unprognostic (2.80e-1)" "unprognostic (7.81e-2)" "unprognostic (7.32e-3)" "unprognostic (3.83e-2)" "unprognostic (4.97e-1)" "unprognostic (2.17e-2)" "unprognostic (6.86e-2)" "unprognostic (1.99e-1)" "prognostic favorable (6.16e-5)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.34e-3)" "unprognostic (3.03e-1)" 2.6 0.1 0.2 2.5 0.4 18.1 0.2 0.2 2.3 0.4 0.3 0.5 58.9 0.1 25.5 0.3 1.2 0.4 0.3 0.1 0.3 18.7 0.5 3.2 0.1 0.5 0.4 0.1 0.2 0.0 0.1 0.3 0.6 0.1 0.2 0.0 0.1 7.1 0.1 0.1 87.6 0.4 0.2 12.6 1.8 1.3 0.6 0.4 0.1 1.0 0.0 0.5 0.1 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 4.3 1.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 2.3 0.1 0.3 0.5 0.4 0.6 0.2 0.6 0.4 0.0 0.0 2.5 3.3 0.1 0.0 0.0 0.6 0.0 0.2 0.5 0.1 1.4 0.0 3.2 12.9 0.0 0.0 2.8 1.8 1.9 0.1 59.7 0.1 0.2 0.3 1.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.7 17.8 0.0 0.0 2.5 156.4 0.6 1.1 0.0 0.0 0.7 0.6 5.2 1.5 0.6 0.2 16.3 0.4 0.0 0.1 521.4 24.4 6.7 0.0 0.0 0.5 0.1 1.8 1.2 0.0 0.0 0.0 0.4 0.0 7.3 0.3 MIA2 "cTAGE-5A, cTAGE-5B, cTAGE-5C, cTAGE-5D, CTAGE5, FLJ22404, MEA6, MGEA, MGEA11, MGEA6, TALI" ENSG00000150527 "MIA SH3 domain ER export factor 2" Q96PC5 14 39230231-39388513 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 44.1;Ductal cells: 42.9;Endometrial ciliated cells: 78.7;Exocrine glandular cells: 42.7;Glandular and luminal cells: 93.5;Pancreatic endocrine cells: 41.3;Proximal tubular cells: 61.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 125.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000387, HPA000922, HPA054066, HPA055459" Approved Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" "HPA000387: AB_1078582, HPA000922: AB_1078581, HPA054066: AB_2682368, HPA055459: AB_2682819" "unprognostic (2.62e-1)" "unprognostic (7.17e-3)" "unprognostic (2.33e-1)" "unprognostic (5.27e-4)" "unprognostic (3.21e-4)" "unprognostic (2.63e-1)" "unprognostic (2.48e-1)" "unprognostic (7.18e-2)" "unprognostic (1.12e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-2)" "unprognostic (1.78e-1)" "prognostic favorable (2.81e-4)" "unprognostic (6.93e-2)" "unprognostic (8.08e-2)" "unprognostic (2.91e-1)" "unprognostic (3.97e-2)" 12.1 26.6 5.6 16.8 6.9 23.6 22.1 5.8 7.9 29.7 58.0 30.8 80.4 15.7 40.2 26.9 22.2 30.3 16.6 9.4 6.5 78.4 138.9 15.5 16.2 5.6 4.7 9.6 43.6 40.5 15.5 11.2 6.4 21.1 34.6 12.8 52.5 19.2 54.5 9.9 78.4 12.3 4.1 14.5 45.3 21.0 5.1 14.3 46.7 20.7 19.8 16.2 17.2 7.1 23.0 25.1 10.4 18.5 20.6 23.2 14.5 13.3 13.9 9.3 9.6 19.7 125.4 27.5 40.1 15.0 18.9 34.1 12.7 15.0 11.0 21.4 10.6 17.2 11.5 106.1 48.2 23.2 30.7 14.4 83.7 9.2 69.2 59.0 15.3 31.8 16.6 68.3 14.0 22.1 14.9 18.9 12.0 87.2 20.8 15.2 18.3 34.9 42.7 24.7 8.7 5.1 31.0 32.5 20.4 13.1 31.2 24.8 24.3 14.1 9.2 10.4 8.8 38.7 35.7 27.2 7.9 14.5 12.0 40.9 16.3 25.9 15.4 18.0 14.0 11.7 11.6 14.4 17.8 13.1 14.2 13.2 34.5 14.6 21.0 12.3 11.8 11.8 5.6 6.9 5.8 7.9 9.4 6.5 5.6 4.7 6.4 4.1 5.1 7.1 26.7 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 33.1 19.9 0.0 5.7 0.0 44.1 0.0 5.6 35.9 0.8 7.9 42.9 0.5 78.7 30.7 7.1 0.0 0.0 0.1 42.7 5.0 4.6 0.0 93.5 0.0 10.3 0.0 3.8 7.6 0.0 0.1 1.8 0.0 0.0 0.0 0.6 0.0 12.7 0.0 0.0 23.8 0.0 1.0 0.0 0.0 41.3 0.0 0.0 8.1 0.0 6.6 61.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.0 13.6 20.0 0.2 0.0 MIEF2 "MGC23130, MiD49, SMCR7" ENSG00000177427 "Mitochondrial elongation factor 2" Q96C03 17 18260597-18266552 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 38.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042334 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" "HPA042334: AB_10794418" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" "unprognostic (7.56e-3)" "unprognostic (1.30e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-2)" "prognostic favorable (1.75e-7)" "unprognostic (4.68e-2)" "unprognostic (1.39e-1)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" 4.8 9.9 3.6 1.5 3.8 1.6 6.0 4.9 4.4 8.8 4.5 6.4 3.6 7.6 4.1 11.4 8.2 2.0 17.1 3.6 3.2 11.9 6.5 5.7 2.3 4.6 3.6 10.2 7.7 6.0 10.5 2.4 3.7 7.8 1.5 2.1 10.6 3.3 24.6 9.6 5.7 1.9 3.0 5.7 6.6 4.9 3.2 1.9 9.8 12.0 1.7 6.2 8.1 3.7 24.0 7.0 2.5 5.5 1.8 2.1 4.4 8.1 4.7 6.6 3.3 9.8 7.4 3.4 8.6 4.0 3.1 17.4 1.8 6.1 3.3 3.3 10.6 1.2 12.0 4.6 3.3 0.6 2.9 2.0 6.3 3.3 2.3 5.4 2.8 4.6 2.9 0.9 2.5 6.8 3.0 2.3 2.1 5.6 3.4 4.2 7.4 4.5 9.2 4.4 1.9 4.3 6.0 7.4 3.4 16.0 18.0 2.1 3.4 4.6 7.5 7.3 3.7 3.6 2.3 1.0 6.6 1.2 2.5 1.6 1.9 6.4 3.5 1.8 3.3 2.1 2.8 2.9 2.0 3.3 3.2 3.4 3.2 7.7 4.7 3.0 3.7 2.1 3.6 3.8 4.9 4.4 3.6 3.2 4.6 3.6 3.7 3.0 3.2 3.7 2.9 16.0 6.0 2.6 4.6 1.9 3.9 6.8 2.8 16.9 5.2 5.5 16.2 1.5 5.6 11.0 16.7 12.0 3.4 6.4 9.8 15.1 14.6 11.4 2.7 4.0 4.2 2.5 2.5 6.0 5.5 4.6 1.5 8.4 2.5 7.0 3.9 3.8 4.1 38.7 3.7 5.4 6.1 2.5 1.1 2.3 8.1 1.6 0.0 1.0 1.9 11.2 6.2 1.5 1.4 21.8 8.6 10.1 3.4 4.2 5.8 5.6 12.5 20.6 6.6 5.2 5.5 2.0 3.8 2.1 1.7 7.7 2.8 10.6 4.6 2.9 MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996086-151008375 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Distal tubular cells: 39.2;Ductal cells: 11.6;Proximal tubular cells: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 98.4;eosinophil: 56.2;neutrophil: 85.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 98.4" "Cell line enhanced" "Detected in many" "T-47d: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028351, HPA028358, HPA061086" Approved Enhanced Nucleoplasm NA NA 220000 "Cluster 2: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA028351: AB_10611110, HPA028358: AB_10601102, HPA061086: AB_2684425" "unprognostic (5.73e-2)" "unprognostic (2.86e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-1)" "unprognostic (3.39e-2)" "unprognostic (6.90e-2)" "unprognostic (1.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (9.22e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.43e-8)" "unprognostic (2.30e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (6.06e-2)" 13.8 13.0 24.9 8.2 49.9 7.2 15.0 42.7 33.7 19.0 30.9 18.4 16.8 18.1 7.0 37.1 17.4 14.0 33.5 22.2 30.7 30.4 19.0 12.9 6.4 58.7 43.9 21.7 47.6 30.1 15.1 6.8 53.4 14.3 17.2 13.3 29.6 13.7 16.7 20.6 14.8 15.6 33.3 15.1 25.9 23.6 43.1 3.6 47.3 18.0 8.7 15.0 20.1 75.6 11.3 7.3 7.7 10.8 13.4 11.1 6.4 3.6 9.1 5.0 7.9 15.6 26.3 0.7 8.4 4.7 1.5 5.5 6.1 6.8 2.2 8.6 9.2 11.0 13.8 13.5 3.0 3.3 4.3 9.1 5.9 9.0 2.5 16.8 12.9 3.8 7.0 27.5 5.3 17.4 0.6 7.4 3.5 3.5 2.5 8.3 1.4 34.8 23.4 22.1 13.1 9.7 6.9 12.4 7.4 3.6 49.5 11.1 12.0 4.3 5.5 2.2 3.1 10.1 9.9 37.5 10.2 7.2 20.4 98.4 9.3 56.2 0.4 4.1 0.3 0.8 3.5 1.0 11.5 1.5 5.8 2.0 85.4 4.7 2.8 1.7 4.8 9.9 24.9 49.9 42.7 33.7 22.2 30.7 58.7 43.9 53.4 33.3 43.1 75.6 4.5 9.6 5.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 8.8 5.8 0.0 0.0 3.7 3.7 0.0 3.8 1.4 0.0 39.2 11.6 0.0 3.4 3.7 3.7 0.0 0.0 0.0 7.0 0.8 2.9 0.0 4.5 3.8 6.4 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 12.0 2.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 2.6 0.8 5.0 0.0 0.0 MKI67 "MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 46.3;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 232.9;Extravillous trophoblasts: 86.1;Granulosa cells: 87.0;Plasma cells: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB000058, HPA000451, HPA001164, CAB068198" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli rim" "Mitotic chromosome" "CAB000058: AB_2142367, CAB068198: AB_2665702, HPA000451: AB_1079186, HPA001164: AB_1079187" "unprognostic (2.54e-1)" "unprognostic (1.29e-1)" "unprognostic (3.37e-1)" "unprognostic (9.92e-3)" "unprognostic (3.17e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (3.61e-6)" "unprognostic (7.16e-3)" "unprognostic (1.45e-2)" "unprognostic (3.73e-1)" "prognostic unfavorable (9.47e-5)" "unprognostic (2.45e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.42e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (4.61e-1)" 0.9 0.7 0.0 8.5 0.1 46.3 1.7 0.0 0.1 1.2 0.2 8.1 6.2 1.0 0.0 10.0 0.3 0.9 0.3 0.1 0.1 0.4 0.8 1.4 14.9 0.1 1.0 0.2 0.2 0.1 0.1 4.1 0.6 0.4 9.2 0.0 1.4 0.1 0.0 6.6 5.8 2.6 0.0 4.8 4.2 2.3 0.9 52.7 0.4 0.1 16.4 1.8 2.8 0.3 204.6 101.5 103.2 73.6 4.3 8.7 32.1 75.7 55.3 70.3 62.3 83.9 82.3 152.6 21.3 51.9 46.4 120.7 109.3 56.8 104.7 161.8 53.1 131.0 79.4 52.7 0.1 186.0 68.0 2.0 2.5 72.2 73.2 17.2 69.8 69.5 61.2 142.1 70.5 80.9 111.7 56.6 41.3 52.7 45.7 82.2 135.1 20.3 25.6 56.2 35.9 38.9 107.1 38.0 17.3 33.9 31.4 39.3 65.0 37.0 73.6 53.0 206.8 64.2 54.9 177.2 30.7 83.3 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 1.0 0.6 0.0 0.9 0.3 0.6 0.0 5.4 0.0 16.0 6.4 1.6 5.3 0.6 0.0 3.9 3.2 1.6 1.5 5.3 0.0 0.0 30.6 7.4 25.0 0.0 0.8 4.2 2.3 10.2 6.7 6.7 232.9 0.0 0.0 86.1 13.5 34.7 13.2 1.3 87.0 5.7 1.7 42.1 0.0 0.0 22.4 2.0 12.9 13.7 0.9 0.3 16.6 3.6 0.0 0.2 0.0 8.2 0.0 0.0 0.1 3.0 0.4 107.4 4.6 2.6 0.1 1.6 0.0 0.0 0.5 13.6 8.1 24.1 50.4 3.0 7.8 23.0 2.7 47.1 4.8 MLEC KIAA0152 ENSG00000110917 Malectin Q14165 12 120687149-120701859 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Undifferentiated cells: 397.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 880000 "Cluster 52: Eosinophils - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 32: U-937 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.50e-1)" "unprognostic (1.74e-1)" "unprognostic (2.01e-2)" "prognostic favorable (9.60e-6)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (5.41e-2)" "unprognostic (3.94e-1)" "unprognostic (3.39e-1)" "unprognostic (9.77e-2)" "unprognostic (5.90e-2)" "unprognostic (1.76e-1)" "unprognostic (1.15e-2)" "prognostic favorable (8.77e-4)" "unprognostic (1.98e-1)" "unprognostic (7.88e-2)" "unprognostic (1.05e-1)" 51.7 93.1 35.4 51.8 36.7 34.6 44.3 33.0 34.5 52.8 40.3 127.0 78.3 37.2 138.1 24.5 48.5 48.5 65.9 34.7 40.0 73.5 78.2 34.9 30.3 42.3 39.4 49.2 62.7 101.2 36.7 45.7 37.8 62.4 117.3 25.3 50.7 64.9 79.8 27.8 86.0 50.0 40.0 30.1 45.3 69.1 42.9 33.3 101.0 82.9 37.3 34.1 17.4 37.6 122.7 177.9 113.6 151.8 196.3 107.4 127.9 144.5 126.3 108.9 80.1 127.5 75.1 100.3 129.0 142.2 85.4 101.9 140.4 87.4 138.7 86.5 76.9 142.4 79.4 100.6 72.1 199.3 123.1 82.2 82.7 116.0 91.4 174.1 97.2 93.9 85.9 112.2 116.3 127.8 106.4 122.2 158.1 156.6 91.7 115.7 82.0 109.1 132.2 204.0 58.2 69.2 166.5 85.9 86.0 143.0 127.0 144.6 79.2 115.8 108.5 112.8 100.3 83.3 165.0 76.8 147.6 147.9 120.1 0.5 6.0 8.0 3.8 7.5 4.1 4.7 2.3 3.4 5.0 6.9 4.0 3.4 1.6 3.9 6.5 18.6 2.4 2.2 35.4 36.7 33.0 34.5 34.7 40.0 42.3 39.4 37.8 40.0 42.9 37.6 151.4 25.6 62.2 23.2 65.7 72.8 70.6 32.0 55.2 40.9 99.7 76.3 145.3 97.2 40.0 86.5 45.9 88.4 105.7 155.3 37.2 134.2 243.3 78.3 127.6 94.1 80.3 68.5 21.4 183.7 176.9 90.5 69.3 80.2 49.5 99.8 27.1 206.1 126.8 84.1 24.7 199.2 30.5 61.7 73.2 228.0 82.6 70.1 193.9 34.7 56.4 81.8 74.2 32.2 23.0 95.8 86.0 108.0 217.4 152.6 135.4 121.7 41.9 45.3 85.5 61.4 78.5 165.6 153.4 52.8 58.7 115.6 51.2 142.5 397.0 82.2 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MOCS2 "MOCO1, MOCS2A, MOCS2B" ENSG00000164172 "Molybdenum cofactor synthesis 2" "O96007, O96033" 5 53095679-53110063 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 573.2;Proximal tubular cells: 281.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037679, HPA037680" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear speckles" "HPA037679: AB_2675604, HPA037680: AB_10673635" "unprognostic (3.27e-1)" "unprognostic (3.11e-2)" "unprognostic (2.82e-1)" "unprognostic (8.37e-3)" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.60e-2)" "unprognostic (1.33e-1)" "unprognostic (6.66e-2)" "unprognostic (7.59e-2)" "unprognostic (2.41e-3)" "unprognostic (1.85e-1)" "prognostic favorable (3.68e-6)" "unprognostic (1.04e-1)" "unprognostic (1.04e-2)" "unprognostic (2.04e-1)" "unprognostic (5.86e-2)" 48.7 79.4 79.1 24.9 84.9 9.1 42.1 80.3 107.6 34.7 74.4 41.9 40.8 30.0 45.9 35.2 26.5 31.3 87.0 84.3 86.3 114.8 126.2 28.2 26.1 79.2 80.5 43.5 42.4 89.6 30.5 35.9 82.4 36.8 32.3 59.3 48.9 44.9 109.3 16.6 40.2 34.4 85.6 23.6 37.2 26.0 88.0 28.3 55.4 111.8 25.2 30.8 24.6 87.4 79.4 62.7 42.9 109.9 85.0 83.2 51.6 99.5 91.9 74.4 89.8 79.7 56.5 76.7 143.5 69.9 127.1 45.0 91.7 96.7 117.2 19.6 84.8 61.7 58.2 75.9 94.4 65.0 43.0 65.1 41.7 91.7 83.5 81.0 85.1 101.4 58.7 44.2 129.5 115.5 72.7 31.8 37.0 34.2 130.1 36.0 93.0 67.0 144.1 56.6 29.4 33.7 69.4 57.3 72.9 56.9 107.2 15.4 55.6 76.9 81.0 69.1 120.5 49.4 84.8 91.5 106.7 16.8 125.1 14.5 21.8 15.6 36.9 26.9 46.2 37.5 42.7 42.8 29.8 40.5 55.3 49.2 3.8 43.5 25.4 27.8 44.9 28.9 79.1 84.9 80.3 107.6 84.3 86.3 79.2 80.5 82.4 85.6 88.0 87.4 51.7 54.5 29.7 14.4 23.5 13.4 40.1 48.5 19.9 30.2 55.7 50.5 122.9 62.9 37.9 69.9 27.1 95.4 19.4 18.2 573.2 43.7 7.3 22.6 29.0 37.6 26.4 18.7 19.1 43.7 37.3 55.7 19.9 26.8 10.1 38.8 26.0 132.6 41.3 6.7 18.4 22.7 44.7 31.2 20.1 14.6 50.7 28.7 23.2 6.5 12.2 67.5 29.9 4.5 11.9 22.1 18.2 68.8 26.7 34.5 65.7 281.7 32.9 21.7 32.9 73.8 49.4 46.7 62.9 37.5 15.6 32.3 25.8 64.2 30.9 34.5 MORN2 MOPT ENSG00000188010 "MORN repeat containing 2" Q502X0 2 38875962-38929072 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 174.2" "Cell type enhanced" "Detected in many" "Early spermatids: 1976.5;Endometrial ciliated cells: 783.4;Late spermatids: 3753.7;Respiratory ciliated cells: 848.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057815 Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA057815: AB_2683537" "unprognostic (7.28e-3)" "unprognostic (3.84e-2)" "unprognostic (8.65e-2)" "unprognostic (1.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.24e-3)" "unprognostic (1.66e-2)" "unprognostic (6.01e-2)" "unprognostic (2.60e-2)" "unprognostic (2.93e-1)" "unprognostic (2.21e-1)" "unprognostic (8.37e-3)" "unprognostic (2.35e-1)" "unprognostic (1.09e-2)" "unprognostic (3.55e-1)" "unprognostic (8.80e-2)" 13.5 30.5 41.9 6.2 44.6 9.7 20.6 42.8 55.9 30.5 62.8 14.5 6.6 16.6 73.3 13.7 96.3 16.0 26.2 42.4 44.9 69.3 17.6 18.0 5.5 45.0 46.4 19.4 20.2 79.5 56.8 8.0 45.7 18.0 13.5 37.6 21.3 18.8 20.0 10.2 8.1 11.3 43.7 6.6 15.2 174.2 43.6 8.2 46.0 17.3 5.7 14.5 13.2 44.3 60.9 30.5 37.2 46.0 40.4 60.5 21.0 27.7 42.9 42.5 40.2 18.3 33.5 3.8 21.8 40.9 42.4 15.9 16.5 34.9 63.4 25.3 32.8 12.9 32.6 46.1 34.8 21.2 9.2 35.6 42.8 51.5 18.9 54.0 39.9 11.7 22.7 8.9 35.8 58.6 9.3 40.5 27.6 40.0 31.7 5.2 38.8 13.3 83.0 33.4 37.1 49.4 41.3 27.0 59.6 21.7 36.5 28.5 26.5 30.2 29.8 48.0 44.1 16.6 26.4 2.3 68.8 6.0 54.4 1.5 8.3 1.2 1.6 6.7 3.1 2.5 1.9 2.4 5.9 2.7 3.2 3.3 0.7 2.7 5.5 3.0 4.0 3.8 41.9 44.6 42.8 55.9 42.4 44.9 45.0 46.4 45.7 43.7 43.6 44.3 14.1 16.0 25.3 2.6 7.9 9.7 25.5 103.9 10.2 16.7 29.5 45.7 40.5 35.8 90.9 60.7 10.4 15.9 4.2 19.5 270.1 61.4 1976.5 783.4 34.1 16.0 22.9 7.4 2.5 44.4 22.9 28.8 18.8 43.6 9.5 35.2 12.8 24.5 23.6 16.8 2.3 18.1 73.2 9.0 6.7 3753.7 53.4 15.1 23.2 0.0 10.2 106.7 3.1 1.5 1.8 41.0 34.3 51.6 5.5 22.4 7.4 396.6 848.6 35.1 26.3 21.3 40.5 530.7 92.0 15.7 10.5 7.7 6.1 51.8 22.0 30.0 MPEG1 MPG1 ENSG00000197629 "Macrophage expressed 1" Q2M385 11 59208510-59212927 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 207.4" "Group enriched" "Detected in some" 4 "dendritic cells: 156.0;Kupffer cells: 409.8;Macrophages: 174.6;monocytes: 218.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 290.5;intermediate monocyte: 209.9;myeloid DC: 144.7;non-classical monocyte: 245.2;plasmacytoid DC: 204.9" "Group enriched" "Detected in many" 6 "dendritic cells: 204.9;monocytes: 290.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA046801 Approved "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA046801: AB_2679814" "unprognostic (1.24e-1)" "unprognostic (2.17e-3)" "unprognostic (1.05e-2)" "unprognostic (2.00e-2)" "unprognostic (3.38e-2)" "unprognostic (2.79e-3)" "unprognostic (7.82e-2)" "unprognostic (1.41e-2)" "unprognostic (6.23e-2)" "unprognostic (2.76e-1)" "unprognostic (5.48e-2)" "unprognostic (3.51e-1)" "unprognostic (1.48e-1)" "unprognostic (9.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.76e-1)" "unprognostic (5.86e-2)" 29.2 15.8 1.5 112.4 1.6 21.3 13.5 1.7 2.4 11.6 3.2 32.9 40.9 10.9 3.7 12.6 6.9 36.2 10.3 1.4 2.1 6.0 41.1 35.4 96.3 3.3 1.9 4.9 4.6 4.6 1.6 35.8 2.5 8.0 43.4 0.3 7.3 9.3 3.9 7.1 52.8 28.2 2.9 207.4 19.2 4.5 4.0 42.8 5.9 8.3 75.2 42.7 2.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 290.5 8.4 0.5 209.9 0.5 12.6 0.3 0.2 144.7 14.0 0.2 0.1 38.5 1.2 245.2 204.9 0.6 214.5 1.5 1.6 1.7 2.4 1.4 2.1 3.3 1.9 2.5 2.9 4.0 4.0 0.7 0.0 7.9 0.0 33.8 1.1 0.0 0.0 1.2 0.0 0.3 0.9 1.7 1.5 0.6 0.0 0.0 0.3 156.0 0.1 0.0 0.0 0.2 0.0 0.1 1.7 0.0 4.4 0.0 0.0 0.6 0.8 0.5 0.1 2.5 0.0 4.6 3.7 52.4 0.0 0.0 0.0 0.0 409.8 48.0 0.6 0.0 174.6 1.8 10.3 218.2 0.2 7.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 6.6 0.7 0.4 0.0 0.0 0.3 1.6 0.3 2.7 0.0 0.0 0.1 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPP5 "FLJ12615, PALS1" ENSG00000072415 "Membrane palmitoylated protein 5" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA000993: AB_1079407, HPA063890: AB_2732707" "unprognostic (3.65e-1)" "unprognostic (3.82e-3)" "unprognostic (4.56e-2)" "unprognostic (9.20e-2)" "unprognostic (9.86e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-3)" "unprognostic (9.89e-3)" "prognostic favorable (1.71e-12)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (6.90e-2)" "unprognostic (6.87e-2)" 7.4 8.7 13.9 6.3 20.9 5.6 10.6 17.6 16.5 8.8 26.6 12.7 20.4 6.3 21.1 13.6 7.3 7.9 7.4 11.9 17.4 31.4 19.6 12.3 4.8 18.2 18.2 6.1 8.7 19.6 7.2 9.8 18.3 16.2 12.0 17.2 18.4 12.7 18.0 8.4 20.7 7.2 18.1 6.6 9.4 8.8 17.5 10.3 25.1 13.6 6.1 9.0 8.4 27.5 156.4 24.4 24.1 18.5 13.3 12.3 20.6 46.4 23.6 33.2 21.6 23.8 45.9 12.7 21.5 37.8 11.0 31.0 13.9 26.1 50.2 5.5 9.5 11.8 23.6 16.8 15.5 4.5 8.5 13.1 10.0 17.9 23.7 24.2 19.0 13.5 12.6 4.7 53.9 20.4 14.4 5.0 7.7 22.2 16.2 12.2 37.1 15.2 30.1 36.8 13.2 9.4 28.2 27.0 15.5 21.1 28.6 9.2 29.2 41.4 87.2 13.8 19.9 7.8 7.6 19.3 27.2 10.1 14.7 0.1 0.5 0.8 0.4 1.0 0.3 1.1 0.5 0.6 0.8 0.4 1.1 0.6 0.0 2.2 0.7 0.6 0.3 0.4 13.9 20.9 17.6 16.5 11.9 17.4 18.2 18.2 18.3 18.1 17.5 27.5 13.2 64.1 28.9 37.2 8.8 21.0 26.0 14.6 22.2 8.5 22.4 12.8 24.7 11.5 21.1 22.0 43.8 23.1 5.2 47.2 13.7 21.7 5.9 29.5 15.0 17.7 5.4 6.7 24.8 26.9 11.3 17.3 18.3 46.2 5.1 15.8 17.2 20.7 17.6 3.3 34.7 21.2 12.2 11.9 13.4 4.5 8.1 9.2 3.6 22.5 6.6 23.4 3.1 41.2 129.8 26.7 32.5 11.3 13.1 30.1 54.3 33.5 14.9 34.3 6.6 17.7 22.2 22.4 36.1 29.2 17.3 17.5 7.7 7.5 22.4 38.7 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MRC1 "bA541I19.1, CD206, CLEC13D, CLEC13DL, MRC1L1" ENSG00000260314 "Mannose receptor C-type 1" P22897 10 17809348-17911164 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 122.3" "Group enriched" "Detected in many" 4 "Breast glandular cells: 128.9;Hepatic stellate cells: 397.7;Hofbauer cells: 176.1;Kupffer cells: 361.4;Macrophages: 316.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 16 "myeloid DC: 4.8" "Lineage enriched" "Detected in single" 16 "dendritic cells: 4.8" "Group enriched" "Detected in some" 19 "MOLT-4: 19.3;TIME: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004114, HPA045134, CAB068203" Enhanced NA NA 170000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "CAB068203: AB_2665652, HPA004114: AB_1846270, HPA045134: AB_2679228" "unprognostic (2.20e-1)" "unprognostic (2.07e-1)" "unprognostic (1.03e-2)" "unprognostic (2.58e-1)" "unprognostic (5.62e-2)" "unprognostic (4.30e-1)" "unprognostic (6.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.05e-2)" "unprognostic (6.05e-2)" "unprognostic (5.61e-2)" "unprognostic (4.12e-1)" "unprognostic (2.94e-2)" "unprognostic (4.97e-2)" "unprognostic (3.05e-2)" "unprognostic (1.74e-2)" "unprognostic (7.02e-2)" 54.4 28.7 0.8 24.0 1.7 0.7 16.3 0.3 3.5 17.2 9.2 16.1 9.9 7.2 1.7 13.1 11.9 27.7 10.2 1.1 0.7 7.6 40.9 122.3 15.2 1.4 0.9 6.2 8.1 4.6 1.5 54.3 1.1 2.2 18.5 0.1 4.9 8.0 1.8 2.8 17.5 30.3 0.7 50.6 9.7 7.5 2.8 8.0 5.5 8.7 3.0 29.0 2.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 19.3 0.0 0.2 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.8 1.7 0.3 3.5 1.1 0.7 1.4 0.9 1.1 0.7 2.8 1.3 4.0 32.1 43.5 1.3 3.5 0.4 0.0 0.0 0.0 0.0 128.9 1.7 3.6 11.5 7.4 0.0 0.0 0.9 1.0 1.4 0.0 0.1 27.3 0.0 0.1 39.0 0.0 3.2 0.8 0.4 1.4 2.5 0.0 0.1 13.9 0.1 397.7 13.1 176.1 0.0 1.3 0.9 0.0 361.4 46.8 19.4 1.5 316.5 0.0 60.9 0.5 0.0 0.0 0.5 0.5 0.1 1.5 0.0 1.0 0.0 2.2 0.1 5.8 0.0 32.9 3.0 2.2 0.4 2.3 1.2 0.4 2.1 4.7 1.7 0.8 0.1 MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261940 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 58.8" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" 9.2 17.0 7.3 6.3 6.9 18.0 11.0 5.4 15.5 10.5 6.4 16.2 13.3 9.1 5.3 17.0 11.0 3.6 14.0 7.5 2.7 17.2 11.7 17.0 7.0 11.8 4.2 7.7 26.7 5.6 22.3 5.5 10.9 17.2 3.4 0.9 17.3 5.7 5.2 17.8 17.6 2.1 1.1 21.7 18.9 13.0 4.9 4.2 58.8 2.1 3.7 12.9 12.6 3.8 17.0 6.9 0.9 6.5 3.1 3.3 29.3 7.3 5.1 4.0 5.5 11.6 29.7 8.9 10.5 4.2 9.8 15.9 1.0 11.2 1.8 5.1 9.5 10.8 22.1 10.7 7.8 4.8 11.0 6.1 11.4 6.4 9.2 4.7 5.8 7.2 4.5 3.9 4.5 36.3 8.4 10.2 2.5 11.6 32.0 10.8 2.2 9.3 5.9 33.0 7.4 6.4 18.3 17.5 5.4 2.5 12.8 6.7 14.6 8.1 15.2 16.6 6.1 6.8 3.6 9.5 16.0 14.3 4.9 4.8 5.7 1.5 1.8 7.5 1.3 0.9 1.5 1.8 4.3 1.5 1.4 1.0 1.1 0.8 6.8 1.3 4.6 2.2 7.3 6.9 5.4 15.5 7.5 2.7 11.8 4.2 10.9 1.1 4.9 3.8 5.2 9.6 26.3 33.0 6.5 6.2 8.5 9.2 6.8 36.4 12.6 9.5 12.4 5.7 16.6 5.5 12.5 31.3 7.0 39.8 3.9 12.2 5.1 17.8 6.7 7.8 23.4 1.7 56.7 16.6 19.2 6.4 63.7 25.2 14.5 14.3 3.9 7.0 19.7 37.0 61.2 24.8 18.3 11.9 11.4 12.2 3.1 14.5 1.8 13.1 11.4 5.7 7.2 14.6 7.9 18.6 17.5 2.6 9.7 17.6 30.7 5.8 18.8 3.5 6.6 7.2 6.7 19.1 26.2 9.7 5.8 50.1 9.1 7.8 22.3 14.8 MRPL17 "MRP-L26, RPML26" ENSG00000158042 "Mitochondrial ribosomal protein L17" Q9NRX2 11 6680385-6683340 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043666, HPA050552" Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" "HPA043666: AB_2678607, HPA050552: AB_2681172" "unprognostic (1.12e-1)" "unprognostic (2.10e-1)" "unprognostic (1.33e-2)" "unprognostic (8.26e-2)" "unprognostic (3.70e-3)" "unprognostic (5.93e-3)" "prognostic unfavorable (2.59e-5)" "unprognostic (4.12e-2)" "unprognostic (2.83e-1)" "unprognostic (2.77e-3)" "unprognostic (1.66e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (6.36e-3)" "unprognostic (2.71e-1)" 19.8 32.0 9.1 16.3 9.4 9.3 15.5 8.4 10.7 11.8 9.2 14.3 15.0 12.8 4.8 29.0 11.0 17.2 29.2 8.7 10.1 22.3 14.7 15.6 22.4 9.3 9.3 10.6 20.2 9.0 26.7 14.9 8.9 12.4 6.4 7.4 19.6 7.8 25.3 14.8 12.0 7.7 9.1 18.7 16.5 12.0 9.8 8.2 20.7 10.3 8.4 15.7 13.8 9.3 108.9 77.6 20.0 11.3 18.8 21.8 45.4 107.0 35.7 43.5 58.3 56.2 70.9 46.5 59.7 21.1 21.7 54.4 17.9 41.6 22.2 75.6 57.7 40.5 45.2 51.8 13.4 41.3 36.3 14.1 18.3 29.9 23.5 17.1 38.3 27.4 20.7 25.1 32.5 79.8 60.4 41.6 41.0 20.6 69.0 43.7 26.6 31.2 29.2 50.5 39.7 30.9 59.3 49.7 65.5 6.4 41.3 35.0 84.7 50.6 49.4 106.8 77.8 33.7 72.9 55.8 89.8 73.9 43.3 6.5 26.8 15.7 25.0 36.3 32.2 39.0 41.5 30.5 35.6 34.1 40.8 28.6 3.6 28.2 24.7 63.5 42.3 30.3 9.1 9.4 8.4 10.7 8.7 10.1 9.3 9.3 8.9 9.1 9.8 9.3 66.8 16.0 17.2 4.6 26.7 52.9 44.2 75.4 38.7 18.0 35.3 46.9 57.1 30.0 42.9 33.1 8.4 101.0 28.4 20.3 121.3 64.8 54.3 38.0 50.5 62.6 21.0 27.3 5.1 72.5 141.5 39.5 30.5 30.8 8.2 34.7 75.7 30.3 89.4 33.7 6.1 44.9 59.0 28.5 23.6 29.5 39.1 27.8 42.7 5.6 39.0 35.1 32.0 5.0 5.8 61.6 27.6 27.1 42.8 53.9 31.1 155.2 38.6 26.7 13.1 23.0 40.9 82.7 35.9 63.7 54.7 36.7 20.4 118.7 49.4 37.4 MRPL40 "MRP-L22, NLVCF" ENSG00000185608 "Mitochondrial ribosomal protein L40" Q9NQ50 22 19432545-19436075 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006181 Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA006181: AB_1079411" "unprognostic (4.12e-2)" "prognostic favorable (7.57e-4)" "unprognostic (2.64e-2)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (4.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (4.08e-2)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (2.67e-2)" "unprognostic (1.75e-1)" "unprognostic (8.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.14e-2)" 39.4 54.4 59.9 26.1 61.6 28.3 47.6 63.9 79.7 50.0 60.3 33.6 26.1 31.3 77.4 35.6 54.8 31.5 100.7 59.0 62.3 69.1 118.8 28.9 35.5 62.5 60.6 44.5 57.1 85.0 11.2 30.7 62.5 46.4 35.9 35.0 72.1 43.0 135.8 29.2 24.7 32.6 63.6 27.1 33.8 31.4 61.7 29.7 79.0 142.0 40.9 36.4 7.0 65.0 84.8 83.8 26.9 64.0 111.5 98.8 45.4 62.1 95.6 116.9 133.6 105.5 49.0 73.2 71.0 93.7 67.8 82.9 118.8 141.2 122.6 69.8 129.7 72.8 76.0 184.4 158.1 117.7 46.1 102.3 123.6 101.1 179.8 77.3 95.6 35.0 265.8 91.2 127.5 106.9 44.9 77.6 22.7 190.2 100.3 49.7 110.6 44.2 135.9 67.9 45.6 48.3 100.7 94.0 159.7 60.2 80.2 52.9 60.6 118.6 127.3 41.6 64.0 78.1 115.7 147.6 79.2 71.6 99.5 45.1 88.3 76.6 71.7 108.9 82.7 162.7 72.4 74.6 100.1 155.6 85.9 75.6 10.4 90.5 90.2 106.5 91.9 103.5 59.9 61.6 63.9 79.7 59.0 62.3 62.5 60.6 62.5 63.6 61.7 65.0 43.3 44.8 35.3 8.8 53.8 40.4 73.3 181.9 52.3 31.0 59.4 85.9 86.1 71.4 106.6 47.8 12.5 129.6 42.9 35.2 260.3 83.8 114.9 104.4 61.9 40.3 34.9 27.1 3.6 97.9 128.9 55.9 32.1 46.1 33.7 44.2 40.0 146.3 135.6 21.9 5.8 47.8 91.6 43.6 40.0 152.4 72.4 42.9 85.4 4.7 73.9 120.4 37.0 3.5 12.0 73.9 48.6 72.2 92.6 53.6 89.8 254.9 163.5 50.3 46.0 53.9 74.3 82.9 72.1 64.8 38.5 62.9 35.1 103.8 49.3 52.2 MRPL43 bMRP36a ENSG00000055950 "Mitochondrial ribosomal protein L43" Q8N983 10 100969458-100987515 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073022 Approved Nucleoplasm,Mitochondria NA NA "Cluster 44: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Mitochondria" "HPA073022: " "unprognostic (2.65e-1)" "unprognostic (1.10e-2)" "unprognostic (2.01e-2)" "unprognostic (4.11e-3)" "unprognostic (6.07e-2)" "unprognostic (3.74e-1)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-2)" "unprognostic (2.03e-1)" "unprognostic (6.04e-3)" "unprognostic (3.02e-1)" "unprognostic (3.53e-2)" "unprognostic (7.29e-2)" "unprognostic (2.53e-2)" 58.5 84.9 26.4 21.0 30.2 25.4 61.6 34.0 37.7 63.3 27.6 69.2 28.6 56.3 7.4 63.7 57.7 18.9 65.2 25.0 27.9 79.4 82.8 45.0 23.6 30.1 29.0 71.4 76.3 27.5 51.7 21.7 30.4 62.5 6.9 9.2 65.7 30.8 117.9 71.8 50.7 7.5 30.5 50.7 68.1 41.1 27.7 12.5 65.3 18.2 7.4 66.5 57.5 34.3 102.5 113.6 23.3 41.5 24.0 30.6 72.4 69.7 62.2 52.9 53.4 65.1 78.0 87.1 92.8 29.3 28.9 62.8 8.5 58.1 7.0 66.4 146.1 68.9 76.6 102.6 51.1 55.1 53.2 47.8 44.6 45.1 19.8 25.2 50.0 54.7 34.9 43.3 16.3 107.7 51.4 124.5 37.9 27.7 105.8 54.7 77.8 59.4 29.4 51.9 26.1 67.6 51.0 24.5 80.7 7.5 130.9 26.1 62.4 49.4 65.9 53.4 74.4 89.9 73.5 44.5 63.1 101.5 36.4 100.4 62.2 70.8 58.0 58.8 59.4 67.1 63.5 57.7 69.7 62.8 59.9 54.9 20.9 72.3 58.7 54.3 77.0 68.0 26.4 30.2 34.0 37.7 25.0 27.9 30.1 29.0 30.4 30.5 27.7 34.3 84.3 44.8 49.6 9.8 64.5 55.7 70.6 97.2 60.3 44.0 93.6 130.8 34.3 88.6 74.7 75.4 41.7 135.3 63.7 47.2 180.0 101.1 114.1 74.3 53.2 58.8 61.1 52.6 8.9 127.2 140.6 68.9 53.5 44.5 46.9 64.8 69.3 75.7 98.4 18.5 13.4 77.7 67.1 51.5 43.6 51.5 85.4 47.6 64.0 7.5 67.6 91.5 71.1 12.1 31.0 91.0 77.4 73.7 70.8 72.0 94.3 221.0 79.7 62.4 52.6 66.1 82.2 277.1 76.6 82.6 68.5 103.7 61.6 98.1 80.6 79.2 MRPL49 "C11orf4, L49mt, NOF, NOF1" ENSG00000149792 "Mitochondrial ribosomal protein L49" Q13405 11 65122183-65127371 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 93.9;Syncytiotrophoblasts: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046778 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA046778: AB_2679802" "prognostic unfavorable (3.79e-4)" "unprognostic (2.21e-1)" "unprognostic (6.07e-3)" "unprognostic (1.05e-1)" "unprognostic (2.50e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-2)" "unprognostic (2.74e-1)" "unprognostic (5.36e-2)" "unprognostic (1.44e-2)" "unprognostic (1.30e-3)" "unprognostic (2.53e-1)" "prognostic favorable (4.22e-15)" "unprognostic (9.09e-3)" "unprognostic (1.12e-2)" "unprognostic (6.68e-2)" "unprognostic (7.45e-3)" 23.1 87.3 25.5 21.9 26.5 26.7 35.2 24.1 27.5 29.4 29.5 33.6 28.1 28.3 41.8 43.0 42.1 21.3 32.4 26.6 29.2 55.1 50.9 28.1 30.9 26.3 25.7 42.8 26.9 42.8 36.0 27.0 26.2 35.4 34.8 16.9 29.2 39.4 38.0 41.6 28.3 30.0 25.3 26.0 29.1 18.1 29.0 33.9 45.8 36.4 44.1 31.1 28.5 23.6 68.7 64.0 48.0 44.0 39.7 26.4 47.9 49.4 73.8 98.9 70.2 77.4 95.2 68.7 70.9 56.2 93.6 69.3 97.7 71.1 78.9 57.5 33.5 64.0 43.3 62.0 63.7 65.8 54.6 43.3 61.7 81.6 119.7 54.6 61.2 82.4 82.7 40.1 59.2 99.4 82.3 70.9 79.8 77.9 87.5 71.2 46.0 91.0 81.5 51.9 69.3 48.9 76.7 98.2 89.3 38.1 174.4 51.1 31.2 41.7 62.5 61.6 46.5 75.5 110.0 141.4 57.2 44.7 72.7 133.5 39.3 78.4 68.2 39.5 77.8 77.9 73.6 83.8 52.1 74.8 81.2 69.3 32.7 95.8 56.8 50.2 74.8 96.2 25.5 26.5 24.1 27.5 26.6 29.2 26.3 25.7 26.2 25.3 29.0 23.6 19.8 16.0 15.9 2.3 20.6 11.1 22.8 21.1 13.1 15.3 22.7 21.6 16.6 20.0 16.6 12.9 10.4 60.4 21.6 23.1 93.9 31.6 1.0 17.4 11.2 16.0 22.7 44.8 5.3 20.3 51.1 14.9 10.2 16.2 12.6 21.6 12.8 17.9 21.5 11.8 4.8 23.5 18.3 6.5 9.9 3.4 14.6 12.4 23.2 1.9 35.4 31.1 13.4 0.5 4.3 28.2 16.6 24.5 24.3 20.8 22.3 49.2 28.6 17.9 6.6 10.4 24.6 5.9 15.6 12.8 16.1 111.0 24.6 77.9 22.9 21.4 MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 427.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA042117: AB_2677856, HPA046767: AB_2679795" "unprognostic (2.09e-1)" "unprognostic (1.00e-3)" "unprognostic (3.81e-2)" "unprognostic (1.85e-3)" "unprognostic (1.00e-1)" "unprognostic (4.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.32e-3)" "unprognostic (7.19e-2)" "unprognostic (1.70e-2)" "unprognostic (2.22e-2)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.26e-1)" "unprognostic (2.64e-2)" "unprognostic (6.54e-3)" 56.1 85.5 68.9 41.0 69.0 109.0 54.8 70.6 80.0 47.0 70.5 54.9 53.8 49.8 36.3 58.4 57.8 34.6 78.6 67.5 70.4 78.7 122.9 43.1 63.5 69.5 68.4 46.9 87.8 71.3 64.0 31.4 69.8 57.9 44.0 38.1 71.9 37.1 57.8 55.9 48.8 37.6 69.8 54.4 70.7 54.4 70.1 63.4 57.8 57.8 50.5 50.4 43.8 72.0 115.1 64.4 58.4 57.6 34.2 54.6 49.6 53.8 69.0 126.8 108.5 55.7 39.8 82.1 54.4 66.8 47.6 71.3 77.6 70.9 53.8 53.0 118.4 41.8 33.6 72.0 89.1 89.7 95.0 64.2 121.3 53.2 92.7 49.0 105.8 56.4 80.2 157.1 67.3 77.9 81.1 94.5 77.8 79.8 46.9 69.4 33.2 122.8 97.8 57.9 81.6 67.6 43.8 103.4 83.4 27.8 69.7 126.6 75.5 79.5 45.8 136.5 117.2 95.4 140.5 82.4 78.6 142.3 60.6 96.9 121.2 81.9 103.4 132.8 96.0 139.1 112.5 122.3 134.7 125.8 107.6 99.1 35.3 133.0 133.7 122.7 168.4 144.1 68.9 69.0 70.6 80.0 67.5 70.4 69.5 68.4 69.8 69.8 70.1 72.0 61.1 76.9 79.3 5.5 101.2 49.1 91.9 111.1 63.2 55.6 89.2 98.8 55.2 91.5 91.7 79.1 18.8 134.4 69.7 183.5 358.1 112.7 94.2 90.1 54.7 60.5 105.4 63.1 3.6 193.6 125.7 62.8 90.7 78.8 106.5 47.6 62.4 249.8 157.7 38.7 4.7 234.8 79.3 115.3 65.4 63.0 56.2 90.9 71.2 2.8 120.7 105.1 106.1 2.0 10.1 128.7 185.4 44.8 123.2 116.2 234.4 427.8 76.0 90.9 26.3 65.7 64.4 113.4 47.1 106.7 57.3 176.9 94.6 109.3 171.5 118.2 MRPL57 MRP63 ENSG00000173141 "Mitochondrial ribosomal protein L57" Q9BQC6 13 21176658-21179084 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 719.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039779, HPA059370" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039779: AB_10673362, HPA059370: AB_2683993" "unprognostic (1.00e-1)" "unprognostic (1.92e-1)" "unprognostic (4.32e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-1)" "unprognostic (5.54e-2)" "unprognostic (1.47e-1)" "unprognostic (1.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.68e-2)" "prognostic favorable (8.35e-4)" "unprognostic (7.65e-2)" "unprognostic (2.01e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-1)" "unprognostic (1.10e-1)" "unprognostic (6.78e-2)" 13.6 27.0 16.0 8.4 16.1 11.0 13.9 16.8 18.3 12.1 15.3 17.2 10.8 12.9 11.7 17.6 13.4 5.2 28.1 16.7 20.5 24.7 29.1 11.7 8.8 16.8 17.0 16.1 16.9 15.3 27.9 7.1 16.9 17.9 6.8 15.5 14.9 8.4 38.8 14.9 13.7 5.6 16.3 14.8 16.2 11.8 17.3 17.0 16.4 18.3 6.6 14.8 12.4 16.5 16.9 30.3 20.8 19.0 15.6 12.8 21.9 20.0 12.4 18.5 13.9 39.6 30.6 9.7 22.7 12.5 14.5 28.7 18.3 19.0 13.9 25.8 30.8 44.2 21.3 45.3 23.2 24.6 21.3 13.2 20.8 14.8 13.9 11.2 17.9 39.0 19.5 12.4 13.2 59.3 53.7 64.8 15.1 54.8 35.0 32.1 31.4 17.2 23.1 20.3 41.4 19.4 16.2 20.1 31.2 14.0 20.2 22.8 12.6 9.6 17.9 20.5 17.9 17.2 14.9 17.7 8.6 28.5 24.6 51.1 70.4 56.3 49.8 59.0 56.4 63.1 62.4 53.2 64.0 60.5 69.6 55.6 10.4 54.5 50.4 102.2 70.2 72.4 16.0 16.1 16.8 18.3 16.7 20.5 16.8 17.0 16.9 16.3 17.3 16.5 93.3 80.1 124.4 12.1 95.4 0.0 107.2 0.0 84.2 88.3 172.1 195.7 495.7 140.2 56.3 176.6 45.9 233.6 118.8 171.7 508.7 159.8 256.0 188.6 98.8 91.6 149.5 165.6 16.8 245.1 205.0 94.2 116.2 107.6 72.2 104.5 117.8 478.4 231.4 77.4 21.3 218.9 0.0 126.6 0.0 341.6 115.2 104.1 0.0 8.4 166.2 181.4 109.2 6.6 17.9 171.6 190.7 98.9 141.9 160.4 266.5 719.5 80.9 100.7 52.6 69.0 74.0 83.6 48.9 175.7 0.0 223.1 99.0 179.5 204.1 112.2 MRPS10 FLJ10567 ENSG00000048544 "Mitochondrial ribosomal protein S10" P82664 6 42206807-42217861 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 295.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029133, HPA029134" Supported Approved "Actin filaments,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Actin filaments" "HPA029133: AB_10600084, HPA029134: AB_10600058" "unprognostic (1.06e-1)" "unprognostic (3.90e-2)" "unprognostic (5.55e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-1)" "unprognostic (1.78e-3)" "unprognostic (2.37e-2)" "unprognostic (8.65e-2)" "unprognostic (1.50e-3)" "unprognostic (5.13e-3)" "unprognostic (2.78e-3)" "unprognostic (6.29e-2)" "unprognostic (3.17e-2)" "unprognostic (8.54e-2)" "unprognostic (3.45e-1)" "unprognostic (3.36e-2)" "unprognostic (5.04e-2)" 24.7 24.0 16.3 20.3 17.1 24.1 21.6 16.8 18.4 19.4 16.1 20.3 19.1 18.3 18.1 43.3 14.5 15.9 46.6 17.3 17.7 29.1 37.5 15.7 24.3 16.5 16.8 14.6 17.2 22.9 13.2 21.6 16.7 18.4 23.6 18.3 19.9 17.0 73.6 18.4 17.7 22.1 16.1 18.8 18.3 16.2 17.5 24.9 24.1 61.8 27.7 24.2 23.7 18.0 99.4 35.1 36.1 61.8 49.4 47.6 32.2 64.3 63.3 61.0 53.3 40.3 38.2 70.2 41.7 60.2 68.3 35.3 60.3 87.5 81.6 64.5 49.3 62.5 30.9 67.2 51.4 93.1 38.8 41.3 65.9 57.2 121.1 41.4 62.8 73.5 110.5 53.4 74.7 63.5 61.0 67.1 30.7 295.3 57.1 51.7 54.3 66.8 105.1 44.2 55.0 40.6 36.9 49.9 122.0 33.5 83.0 125.2 40.7 51.7 51.0 50.3 96.9 39.6 64.4 149.1 35.3 91.7 52.6 22.4 26.0 20.1 23.9 30.4 28.2 30.1 29.2 28.7 29.4 27.1 29.6 28.9 13.1 29.8 28.8 37.7 35.1 28.0 16.3 17.1 16.8 18.4 17.3 17.7 16.5 16.8 16.7 16.1 17.5 18.0 40.4 22.4 21.6 6.8 41.8 40.5 53.6 61.5 22.8 26.8 35.3 33.4 131.8 20.0 39.6 38.6 31.3 102.0 48.0 25.2 92.0 66.5 7.6 35.3 52.4 41.3 14.9 74.5 7.6 47.0 67.5 42.9 23.4 26.8 32.9 46.1 24.7 58.9 52.8 32.0 9.0 27.6 67.1 24.4 28.0 8.8 28.9 34.8 30.2 2.8 110.6 47.8 60.8 7.5 9.5 61.1 30.5 36.5 41.9 64.9 30.0 86.9 60.5 57.3 19.7 35.2 43.0 75.5 83.8 62.2 40.6 75.4 33.8 65.7 35.3 69.4 MRPS18A "FLJ10548, MRPS18-3" ENSG00000096080 "Mitochondrial ribosomal protein S18A" Q9NVS2 6 43671202-43687791 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 370.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035450, HPA035451" Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA035450: AB_10670701, HPA035451: AB_10602029" "unprognostic (9.85e-2)" "unprognostic (3.08e-1)" "unprognostic (2.04e-1)" "unprognostic (7.35e-3)" "unprognostic (2.00e-1)" "unprognostic (1.15e-2)" "unprognostic (4.81e-2)" "unprognostic (1.25e-1)" "unprognostic (5.16e-2)" "unprognostic (1.41e-2)" "unprognostic (3.86e-2)" "unprognostic (9.15e-2)" "unprognostic (2.14e-2)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "prognostic favorable (4.03e-5)" "unprognostic (9.35e-2)" 34.5 44.1 37.0 21.0 37.9 21.5 33.3 37.8 43.4 31.5 53.8 42.6 36.3 32.4 20.9 58.3 30.1 20.4 66.7 39.2 37.7 46.9 63.3 25.6 22.7 38.8 38.1 21.9 32.3 39.1 19.5 22.7 37.7 39.5 45.4 15.0 35.1 26.8 149.4 41.7 31.3 27.1 38.2 32.1 56.1 17.5 39.4 26.4 28.4 103.4 33.1 34.8 33.9 38.1 71.0 57.7 45.2 63.9 45.2 30.4 51.4 32.9 50.2 78.6 77.3 118.7 28.4 29.6 55.4 46.0 64.1 56.6 64.3 92.5 40.9 45.6 76.5 55.7 44.3 104.5 78.1 76.1 32.4 41.4 73.5 66.6 100.6 40.2 59.9 73.0 97.9 61.4 47.0 115.2 58.3 63.4 33.6 370.3 46.2 48.8 35.9 95.9 59.1 79.9 72.5 38.9 34.7 64.5 121.8 32.1 65.5 106.7 32.6 49.4 56.4 40.2 60.2 67.1 60.2 110.3 66.2 52.8 134.8 106.6 69.8 76.8 79.1 60.9 74.8 135.4 73.6 76.0 82.3 98.3 73.0 67.9 32.5 93.3 45.2 91.2 86.9 84.1 37.0 37.9 37.8 43.4 39.2 37.7 38.8 38.1 37.7 38.2 39.4 38.1 27.1 32.1 24.5 5.2 31.8 33.4 44.6 97.7 12.0 13.6 29.1 26.4 1.3 30.0 61.2 33.1 2.1 72.7 15.6 96.0 99.7 78.2 16.5 26.2 26.2 25.3 32.3 23.5 5.1 67.4 64.0 24.6 56.6 43.7 26.6 28.8 30.4 51.8 51.1 8.4 4.5 73.4 73.2 17.5 19.8 35.2 22.7 16.5 40.9 7.5 51.7 23.4 29.9 9.0 5.2 69.3 94.2 21.1 42.9 45.0 73.4 115.4 34.7 15.5 32.9 24.7 25.8 27.3 36.2 31.0 27.3 67.5 19.5 61.7 97.2 77.9 MRPS26 "C20orf193, dJ534B8.3, MRP-S13, MRP-S26, RPMS13" ENSG00000125901 "Mitochondrial ribosomal protein S26" Q9BYN8 20 3046052-3048250 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045472, HPA054610" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA045472: AB_10962052, HPA054610: AB_2682541" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (3.71e-1)" "unprognostic (4.41e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (8.13e-3)" "unprognostic (3.14e-1)" "unprognostic (6.83e-2)" "unprognostic (8.21e-2)" "unprognostic (9.65e-3)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (3.77e-1)" "unprognostic (4.11e-2)" "unprognostic (2.95e-1)" "unprognostic (3.93e-3)" 36.9 69.5 61.1 17.1 62.4 18.1 38.3 63.9 69.6 41.6 64.2 50.8 26.9 40.9 34.8 48.6 42.4 11.3 69.7 59.7 65.3 60.6 104.1 27.9 19.2 64.8 62.0 48.0 50.0 38.9 64.8 19.4 63.5 56.3 18.8 14.2 41.0 30.4 56.7 48.6 35.7 19.8 60.6 34.9 45.4 21.3 63.5 18.3 51.1 25.6 20.9 48.6 38.3 63.7 119.0 157.5 34.7 63.6 37.3 28.4 91.0 45.4 30.6 51.4 39.2 138.9 53.0 117.7 56.3 23.7 67.0 109.9 69.6 94.1 29.9 30.2 149.0 53.6 60.8 234.6 51.9 85.2 25.3 32.0 72.0 42.7 64.2 35.7 38.7 68.9 88.1 27.0 31.1 103.6 88.4 149.6 170.8 89.9 154.0 96.4 60.0 126.5 51.2 78.9 108.9 140.7 52.0 171.7 109.2 34.3 77.4 47.5 36.2 33.2 52.6 60.0 84.9 120.0 169.0 72.6 21.6 70.7 37.8 36.1 64.2 33.0 68.6 77.5 87.9 114.4 76.3 74.6 87.5 104.9 87.3 74.9 5.1 97.0 63.6 53.3 65.9 73.2 61.1 62.4 63.9 69.6 59.7 65.3 64.8 62.0 63.5 60.6 63.5 63.7 50.9 16.0 26.8 18.3 61.4 82.0 62.9 113.7 86.6 40.0 87.4 136.5 64.6 54.3 61.5 55.2 35.5 188.1 50.2 72.6 209.4 77.6 4.3 56.9 70.8 43.1 55.1 49.2 20.3 54.8 117.5 57.6 60.1 50.3 14.0 94.0 32.5 120.0 81.1 47.1 20.3 104.1 103.7 23.6 37.5 10.6 69.0 29.2 67.6 5.6 35.3 88.5 56.7 18.1 19.3 52.6 62.0 61.7 46.2 115.3 108.6 239.8 44.4 45.4 59.2 47.3 66.8 60.8 68.7 101.9 92.2 78.5 44.8 164.6 124.2 54.0 MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 359.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" 47.5 88.8 65.1 32.9 67.7 29.1 47.5 70.0 85.3 33.3 73.0 52.9 30.9 27.3 38.3 41.0 35.2 28.8 104.0 64.0 70.2 79.2 110.9 30.4 37.7 70.1 69.8 28.6 32.3 69.6 40.4 40.9 70.1 31.3 41.0 51.7 35.4 33.4 160.3 29.0 29.4 32.8 69.7 26.7 35.3 24.3 66.9 44.9 53.7 137.7 37.9 39.0 30.7 75.3 85.2 84.1 73.0 17.3 60.9 77.2 79.8 94.3 85.7 122.1 104.2 74.0 66.4 107.2 105.3 75.6 124.2 68.5 102.1 105.5 99.0 85.3 89.8 128.8 74.8 114.4 67.7 57.6 55.3 66.4 88.9 71.8 97.4 67.1 81.0 85.2 93.4 42.3 123.7 81.3 133.8 93.5 29.8 219.5 139.5 89.9 58.1 62.0 158.0 81.8 34.8 58.6 41.1 359.5 91.1 83.8 86.6 68.1 59.0 45.8 116.4 81.6 82.7 46.5 81.4 97.2 77.4 66.7 36.8 95.4 53.8 29.1 48.2 77.3 52.3 51.2 52.8 59.4 98.8 54.4 64.1 62.1 11.1 71.5 70.1 111.1 73.0 49.8 65.1 67.7 70.0 85.3 64.0 70.2 70.1 69.8 70.1 69.7 66.9 75.3 32.5 22.4 22.2 57.8 20.8 35.2 19.5 124.5 36.5 10.9 23.4 28.1 51.6 42.9 67.0 33.1 4.2 78.7 20.9 18.1 101.8 67.3 15.1 28.5 16.1 26.2 37.3 21.7 39.0 47.4 74.3 21.2 17.9 24.1 50.0 10.5 23.9 65.5 49.5 5.0 42.5 23.5 69.2 25.5 28.5 10.4 17.7 26.9 44.4 70.3 40.0 23.7 26.8 93.5 81.8 36.0 20.6 22.2 19.9 13.4 24.5 126.9 79.7 17.2 32.9 31.1 26.1 18.6 33.4 41.6 37.8 59.4 20.0 23.2 36.4 16.0 MRPS30 "PAP, PDCD9" ENSG00000112996 "Mitochondrial ribosomal protein S30" Q9NP92 5 44808947-44820428 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018686, HPA021149" Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018686: AB_1854127, HPA021149: AB_1854128" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (4.48e-1)" "unprognostic (2.94e-2)" "unprognostic (5.47e-2)" "unprognostic (3.54e-2)" "prognostic unfavorable (5.91e-4)" "unprognostic (1.01e-1)" "unprognostic (1.64e-2)" "unprognostic (2.15e-1)" "unprognostic (1.05e-1)" "unprognostic (2.45e-2)" "prognostic favorable (2.87e-9)" "unprognostic (2.20e-2)" "unprognostic (5.04e-1)" "unprognostic (7.01e-2)" "unprognostic (8.70e-3)" 13.1 13.4 4.0 8.5 6.3 25.3 14.1 7.3 9.0 9.5 2.6 13.8 13.4 10.3 5.9 16.6 10.5 5.8 24.5 6.2 2.1 15.1 21.4 8.5 11.7 0.5 1.9 9.4 12.9 12.7 6.4 7.5 1.1 8.7 10.8 6.4 11.6 6.4 35.6 20.5 12.0 7.3 1.9 11.3 12.0 11.5 3.5 10.1 12.0 26.7 9.6 11.4 10.9 7.6 33.2 32.5 19.2 36.9 14.0 16.3 61.9 16.2 17.4 22.8 16.1 51.9 40.5 50.4 55.1 10.7 52.6 30.6 37.7 24.2 20.3 32.7 64.5 37.5 67.8 40.8 31.1 51.5 29.8 16.2 24.4 23.9 29.4 17.2 21.7 27.4 58.5 45.6 21.4 28.3 33.3 67.7 32.4 26.0 57.6 31.3 32.1 67.6 34.6 24.1 29.3 22.9 75.1 40.1 52.2 14.5 36.2 38.0 21.4 26.8 39.6 22.3 51.0 24.4 31.0 41.0 22.6 68.4 27.7 26.0 24.0 18.7 30.9 27.2 32.3 37.8 34.2 34.2 25.6 31.7 40.0 33.9 4.4 35.2 33.3 19.4 46.1 33.6 4.0 6.3 7.3 9.0 6.2 2.1 0.5 1.9 1.1 1.9 3.5 7.6 22.1 25.6 16.5 4.6 31.7 48.8 38.8 63.3 26.7 31.3 23.6 21.1 60.2 17.2 31.5 5.5 18.8 40.0 37.6 21.4 33.2 36.5 105.1 21.3 29.4 23.9 28.7 18.7 14.4 33.1 38.0 24.1 21.4 22.5 19.0 24.1 17.9 26.9 32.5 32.0 8.0 24.5 30.5 16.6 15.7 14.3 20.8 18.9 17.8 3.7 26.3 20.4 26.8 3.5 6.9 29.6 22.8 18.0 20.1 27.6 25.6 35.4 21.9 26.3 13.1 24.9 28.7 43.4 26.4 28.6 75.0 18.6 32.6 32.6 37.0 42.3 MRPS33 CGI-139 ENSG00000090263 "Mitochondrial ribosomal protein S33" Q9Y291 7 141002610-141015228 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 354.1;Proximal tubular cells: 386.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030425 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA030425: AB_10602030" "unprognostic (9.83e-2)" "unprognostic (2.91e-1)" "unprognostic (2.19e-2)" "unprognostic (1.01e-1)" "unprognostic (1.79e-2)" "unprognostic (4.03e-2)" "unprognostic (5.99e-2)" "unprognostic (3.82e-1)" "unprognostic (3.66e-2)" "unprognostic (4.55e-3)" "unprognostic (6.94e-3)" "unprognostic (4.26e-1)" "unprognostic (9.80e-3)" "unprognostic (1.16e-1)" "unprognostic (9.52e-2)" "unprognostic (1.01e-1)" "unprognostic (3.52e-2)" 37.7 64.4 43.9 27.5 46.9 25.0 58.5 46.4 68.8 30.3 47.7 65.3 50.1 25.5 79.1 46.3 35.1 22.4 114.5 45.3 48.0 72.7 83.7 20.8 41.0 46.6 45.9 35.2 67.6 81.2 49.1 24.4 48.0 36.6 69.8 29.4 50.0 31.2 173.7 35.9 44.5 26.5 46.8 30.9 44.3 45.3 45.4 41.9 51.7 171.5 43.5 36.9 30.2 47.8 79.0 110.5 61.8 65.7 77.1 104.9 67.6 69.5 68.7 65.1 73.2 67.6 104.9 107.7 100.0 67.3 140.9 50.5 69.5 102.6 89.3 96.6 83.1 67.8 20.6 130.8 93.8 98.3 39.2 99.8 103.0 100.8 89.4 73.3 53.9 108.4 113.3 84.0 128.2 124.8 110.1 153.3 129.3 140.0 125.6 28.4 48.5 186.1 114.9 99.8 111.7 88.2 93.7 93.2 145.5 65.3 79.4 90.8 41.8 56.6 38.4 137.5 75.8 128.3 155.7 126.8 125.3 99.8 95.1 13.0 47.6 37.9 48.9 68.7 61.9 85.4 85.5 61.1 79.5 66.8 98.3 83.5 4.9 79.8 60.5 93.8 77.3 61.2 43.9 46.9 46.4 68.8 45.3 48.0 46.6 45.9 48.0 46.8 45.4 47.8 30.3 38.5 43.6 11.1 54.6 42.6 72.1 207.7 51.2 27.1 101.1 104.6 333.5 82.9 96.5 114.0 31.3 145.4 39.5 96.9 354.1 101.0 136.8 124.2 60.1 42.8 89.7 46.3 8.9 136.8 133.0 55.3 50.0 70.6 48.2 71.4 42.5 221.8 114.1 57.2 9.1 148.3 109.9 59.8 38.1 41.0 57.8 45.7 76.5 8.4 97.4 47.8 51.5 9.0 18.0 95.6 80.6 42.5 88.9 67.1 199.0 386.1 122.5 32.9 19.7 41.0 57.1 157.7 50.8 84.4 45.7 116.8 49.6 82.8 202.3 79.0 MRPS35 "MDS023, MRPS28" ENSG00000061794 "Mitochondrial ribosomal protein S35" P82673 12 27710822-27756295 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 242.6;Proximal tubular cells: 231.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038513 Supported Approved Mitochondria,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA038513: AB_10794084" "prognostic unfavorable (9.41e-4)" "unprognostic (8.35e-2)" "prognostic favorable (5.01e-4)" "unprognostic (2.59e-2)" "unprognostic (5.31e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (7.32e-2)" "unprognostic (2.12e-3)" "unprognostic (2.05e-1)" "unprognostic (3.24e-2)" "unprognostic (7.19e-2)" "prognostic favorable (1.51e-5)" "unprognostic (4.63e-2)" "unprognostic (2.44e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" 27.3 42.1 25.0 26.8 26.1 31.2 42.7 26.7 33.4 23.8 28.0 59.2 52.6 25.8 29.4 35.8 29.4 24.1 62.2 26.0 27.2 78.6 77.7 21.6 31.9 25.7 26.0 26.2 27.8 46.9 14.0 29.1 26.5 31.5 61.1 18.4 29.6 24.1 83.3 23.5 46.4 29.8 26.7 21.0 43.9 18.0 26.4 28.3 44.2 72.5 32.1 35.3 20.4 27.9 95.0 102.1 42.4 65.1 58.9 71.8 156.0 61.4 52.6 84.4 76.2 125.0 132.4 88.2 87.5 63.3 65.5 70.0 88.0 77.9 99.1 74.2 82.8 100.2 39.2 103.7 58.5 138.1 51.1 61.4 95.1 71.1 143.2 77.3 69.6 73.0 110.1 58.6 77.9 57.9 96.7 227.0 158.9 231.8 147.7 101.1 109.8 145.3 130.8 77.3 24.0 48.5 84.4 131.0 106.1 93.9 133.6 108.2 54.5 51.4 54.9 117.8 111.4 22.8 36.9 186.8 68.6 104.5 68.5 11.0 21.5 7.8 15.1 38.3 24.1 20.7 18.9 18.7 30.5 19.7 22.3 20.4 1.2 25.9 46.4 14.4 26.4 23.8 25.0 26.1 26.7 33.4 26.0 27.2 25.7 26.0 26.5 26.7 26.4 27.9 25.0 73.7 40.3 13.4 38.2 47.3 42.3 65.0 46.1 20.8 49.8 43.8 94.8 50.1 55.4 51.5 4.2 104.0 21.2 51.8 242.6 92.0 12.6 42.0 42.4 30.1 60.3 26.3 28.0 59.2 113.4 35.9 72.4 40.0 54.5 34.5 18.9 67.1 73.1 18.5 28.0 81.2 40.7 38.4 28.8 9.1 25.4 42.9 42.7 8.4 64.7 27.1 34.0 19.6 25.4 62.2 52.3 24.5 32.1 55.4 63.6 231.4 70.2 18.0 26.3 35.8 39.8 23.9 27.2 68.7 52.1 61.7 34.8 83.8 116.5 46.1 MS4A4A "CD20L1, MS4A4, MS4A7" ENSG00000110079 "Membrane spanning 4-domains A4A" Q96JQ5 11 60185657-60318080 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 63.1" "Group enriched" "Detected in many" 7 "Hofbauer cells: 376.8;Kupffer cells: 445.0;Macrophages: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 61.2;myeloid DC: 27.6;non-classical monocyte: 82.9;plasmacytoid DC: 27.7" "Group enriched" "Detected in many" 30 "dendritic cells: 27.7;monocytes: 82.9" "Cell line enhanced" "Detected in some" "HEL: 35.6;HMC-1: 45.8;K-562: 154.9" HPA029323 Approved NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" "HPA029323: AB_10601866" "unprognostic (7.93e-2)" "unprognostic (2.05e-2)" "unprognostic (1.37e-3)" "unprognostic (1.98e-1)" "unprognostic (4.46e-2)" "unprognostic (2.31e-1)" "unprognostic (9.66e-2)" "unprognostic (1.59e-1)" "unprognostic (4.56e-1)" "unprognostic (6.65e-2)" "unprognostic (8.10e-2)" "unprognostic (2.11e-1)" "unprognostic (5.02e-3)" "unprognostic (3.32e-2)" "unprognostic (4.66e-2)" "unprognostic (4.89e-2)" "unprognostic (4.21e-2)" 42.8 24.7 3.5 16.5 3.6 6.1 12.3 3.7 8.6 14.1 4.4 14.0 5.2 4.9 3.4 8.9 11.6 25.8 8.4 3.5 3.9 4.8 15.4 28.0 31.3 4.2 3.4 4.1 4.0 3.3 3.3 63.1 3.6 3.4 16.1 2.0 7.6 4.9 2.3 2.9 13.5 20.0 2.5 33.3 6.6 3.0 5.5 11.5 3.7 10.4 7.5 28.0 3.3 4.3 0.3 0.1 0.1 0.6 0.0 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.9 0.8 0.4 0.0 0.4 0.3 0.5 0.1 0.6 1.6 0.0 35.6 0.7 0.6 0.1 1.2 45.8 0.4 0.3 0.2 0.8 0.2 0.0 0.4 154.9 4.2 0.6 0.7 0.6 0.9 0.7 0.3 0.1 0.7 0.0 2.5 0.1 1.5 0.5 0.5 0.3 0.3 0.1 0.7 0.7 8.9 0.8 1.5 0.6 0.4 0.2 6.0 0.7 0.5 0.2 0.8 0.2 0.1 9.9 0.0 0.1 61.2 0.2 1.0 0.1 0.1 27.6 0.3 0.2 0.1 0.9 1.8 82.9 27.7 0.1 6.0 3.5 3.6 3.7 8.6 3.5 3.9 4.2 3.4 3.6 2.5 5.5 4.3 2.3 0.0 7.9 0.0 3.0 1.8 0.1 0.0 0.6 0.0 0.3 2.2 3.4 2.8 2.5 0.0 0.0 1.8 7.5 0.0 0.0 0.0 0.7 0.0 0.0 5.7 0.0 13.0 0.1 0.0 2.0 1.6 0.0 0.0 7.6 0.0 47.5 4.6 376.8 0.0 0.1 0.0 0.0 445.0 24.9 1.0 0.9 264.6 3.6 10.3 8.3 0.4 0.0 0.0 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 13.1 1.2 1.1 0.1 0.2 0.7 1.8 3.6 1.5 0.1 0.0 0.1 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MT1X "MT-1l, MT1" ENSG00000187193 "Metallothionein 1X" P80297 16 56682470-56684196 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 4031.0;skeletal muscle: 6099.6" "Group enriched" "Detected in many" 4 "Hepatocytes: 12792.4;Proximal tubular cells: 14889.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1069.7;HBEC3-KT: 1964.6;NTERA-2: 670.6;U-87 MG: 720.2" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (8.15e-2)" "unprognostic (9.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.18e-3)" "unprognostic (7.05e-3)" "unprognostic (7.26e-3)" "unprognostic (9.49e-3)" "unprognostic (9.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.40e-2)" "unprognostic (4.85e-3)" "unprognostic (3.84e-1)" "prognostic unfavorable (1.82e-10)" "unprognostic (1.56e-1)" "unprognostic (4.25e-2)" "unprognostic (4.11e-1)" "unprognostic (1.37e-3)" 1445.8 168.5 452.1 105.1 574.1 28.3 1082.7 533.4 587.3 486.3 353.3 359.0 107.8 126.6 98.7 1045.3 379.7 96.5 389.8 426.4 474.5 798.8 4031.0 556.9 44.9 514.5 537.0 186.3 1598.7 32.0 251.0 16.0 519.9 505.2 209.2 75.7 584.9 51.6 6099.6 1768.6 214.8 126.9 496.4 43.0 671.7 58.6 575.1 82.4 1025.4 2145.7 116.2 213.7 911.9 483.8 45.0 47.9 1.9 95.2 1069.7 237.5 37.1 142.3 91.7 39.2 43.8 9.0 41.0 35.4 36.6 35.1 47.6 397.4 131.4 1964.6 46.4 135.0 80.7 46.3 26.7 16.4 152.4 298.1 105.2 238.8 375.9 94.7 98.4 35.8 9.1 34.4 8.0 13.1 135.1 124.5 60.9 317.6 670.6 2.8 314.3 62.9 5.5 90.8 394.0 5.7 95.6 33.3 429.1 107.6 30.7 35.1 12.4 75.0 21.0 81.3 97.5 82.4 99.3 14.3 12.3 14.8 720.2 488.8 48.0 73.1 58.0 19.1 75.3 26.9 86.1 15.6 83.5 94.4 58.5 11.7 78.9 98.4 3.1 24.8 11.7 20.1 90.1 52.3 452.1 574.1 533.4 587.3 426.4 474.5 514.5 537.0 519.9 496.4 575.1 483.8 1563.0 67.3 22.1 47.7 116.0 1747.7 967.7 2932.2 1361.9 0.0 367.7 963.0 158.0 290.2 957.0 581.2 0.0 8.7 162.5 1163.7 2111.0 120.5 2.8 784.0 199.0 256.6 143.9 320.4 2.2 100.3 642.6 621.1 481.2 1883.3 38.7 133.1 307.3 12792.4 67.1 0.0 0.8 1150.7 321.4 327.1 150.8 12.6 495.5 382.8 241.9 4.7 66.7 0.0 41.2 7.5 1.4 174.4 2750.0 118.1 162.8 956.5 3283.6 14889.1 180.0 0.0 72.3 2927.3 670.4 1.6 2.7 1963.3 2398.1 68.4 196.6 77.2 1288.2 265.7 MTARC1 "FLJ22390, MARC1, MOSC1" ENSG00000186205 "Mitochondrial amidoxime reducing component 1" Q5VT66 1 220786913-220819659 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 192.3;breast: 86.2;liver: 84.5" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 109.8;Extravillous trophoblasts: 47.9;Syncytiotrophoblasts: 75.1" "Cancer enhanced" "Detected in many" "prostate cancer: 14.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 30.2;classical monocyte: 33.6;eosinophil: 12.3;neutrophil: 42.8" "Group enriched" "Detected in many" 31 "granulocytes: 42.8;monocytes: 33.6" "Cell line enhanced" "Detected in many" "BEWO: 126.5;HeLa: 56.2;Hep G2: 67.6;NTERA-2: 57.8;OE19: 49.4" HPA028702 Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA028702: AB_10601135" "unprognostic (3.15e-2)" "unprognostic (1.27e-1)" "unprognostic (2.16e-2)" "unprognostic (5.04e-2)" "unprognostic (2.90e-1)" "unprognostic (2.31e-1)" "unprognostic (3.71e-3)" "unprognostic (1.39e-1)" "unprognostic (7.51e-2)" "unprognostic (7.71e-3)" "unprognostic (3.71e-1)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.85e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-1)" 192.3 7.4 9.4 6.8 10.5 17.9 86.2 9.8 13.2 7.9 7.9 18.9 7.6 2.8 14.0 7.6 6.2 4.1 8.4 10.0 11.7 10.2 84.5 9.3 2.8 10.1 11.8 5.5 9.6 5.4 7.0 16.0 9.6 36.2 17.3 5.7 27.2 13.5 11.0 3.6 9.7 4.0 9.1 10.2 9.3 1.4 14.3 1.6 53.5 9.2 2.1 8.8 5.0 8.5 15.0 7.8 5.9 0.2 1.3 0.3 126.5 1.4 1.2 0.8 1.5 45.4 1.0 0.1 5.3 1.6 0.1 0.1 28.3 2.9 2.1 0.2 25.7 0.1 56.2 67.6 2.7 0.3 0.5 4.5 1.3 0.2 0.0 0.2 1.1 0.1 4.3 0.3 1.1 14.7 0.1 31.9 57.8 49.4 23.8 0.1 0.0 0.3 7.1 17.4 16.4 36.1 8.1 11.4 0.2 16.4 38.5 34.7 0.4 0.1 12.6 0.1 0.1 0.2 0.1 0.1 0.2 0.0 1.1 30.2 33.6 12.3 0.1 2.5 0.0 0.4 0.0 0.0 1.2 0.2 0.1 0.0 42.8 0.0 1.3 0.3 0.0 9.2 9.4 10.5 9.8 13.2 10.0 11.7 10.1 11.8 9.6 9.1 14.3 8.5 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 109.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 47.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 75.1 0.0 0.0 0.0 0.0 MTHFS HsT19268 ENSG00000136371 "Methenyltetrahydrofolate synthetase" P49914 15 79833585-79897379 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 253.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 205.5;monocytes: 150.8;Proximal tubular cells: 201.6;Syncytiotrophoblasts: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 134.1" "Group enriched" "Detected in all" 5 "granulocytes: 134.1;monocytes: 49.1" "Low cell line specificity" "Detected in many" "HPA008067, HPA054177" Approved Supported Cytosol NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "HPA008067: AB_1078882, HPA054177: AB_2682405" "unprognostic (4.57e-2)" "unprognostic (9.76e-2)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (9.13e-3)" "prognostic favorable (1.29e-6)" "unprognostic (1.34e-2)" "unprognostic (1.03e-1)" "unprognostic (6.18e-3)" "unprognostic (2.91e-2)" "unprognostic (2.76e-1)" "prognostic favorable (2.04e-4)" "unprognostic (1.36e-1)" "unprognostic (2.85e-1)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" 21.9 19.8 8.0 4.6 8.2 5.0 19.0 9.6 12.7 9.9 6.9 12.0 13.7 9.0 10.3 10.1 9.4 7.0 19.0 8.0 9.2 53.1 253.4 17.8 6.4 8.7 9.3 8.6 32.8 26.3 21.5 8.3 9.1 19.5 6.4 5.9 13.6 5.5 20.2 6.2 14.5 6.2 8.8 14.9 19.5 12.1 8.7 10.6 15.9 11.1 10.8 12.4 9.9 9.1 12.6 35.8 5.0 2.6 15.8 12.0 11.9 8.8 13.0 16.4 10.5 34.5 22.4 15.1 25.1 15.5 15.0 19.5 31.9 10.7 15.4 14.7 28.4 14.8 22.9 39.8 25.3 7.8 0.8 17.5 27.8 8.1 23.0 19.6 7.4 16.0 28.8 12.0 17.4 36.0 10.2 36.1 15.6 51.4 17.0 10.8 17.2 25.8 35.1 34.3 8.9 4.8 25.1 14.2 43.8 20.0 17.3 13.0 3.3 5.7 11.1 3.6 7.1 6.8 20.2 17.8 3.3 25.9 6.2 17.5 25.7 73.5 9.4 35.3 12.4 13.5 13.7 12.9 12.3 11.1 16.5 12.6 134.1 17.8 49.1 13.3 15.7 19.1 8.0 8.2 9.6 12.7 8.0 9.2 8.7 9.3 9.1 8.8 8.7 9.1 11.3 19.2 44.0 0.0 20.7 10.7 9.9 63.0 35.9 0.0 25.5 32.5 0.7 58.6 34.3 22.0 0.0 68.1 10.1 10.0 64.6 55.8 2.2 11.9 7.8 10.5 17.6 36.6 0.0 75.7 37.1 13.5 39.8 11.0 8.8 7.2 21.8 205.5 45.7 0.0 0.0 18.7 24.4 22.1 34.8 3.8 13.7 29.3 21.4 0.0 150.8 0.0 35.0 0.0 0.0 75.3 35.9 15.8 13.3 13.3 101.7 201.6 29.9 0.0 13.1 8.4 10.5 6.7 8.5 21.1 8.1 253.8 22.2 9.2 24.9 7.7 MYCBP AMY-1 ENSG00000214114 "MYC binding protein" Q99417 1 38862493-38873368 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 106.0;Respiratory ciliated cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041188, HPA078331" Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Mitochondria "HPA041188: AB_10794405, HPA078331: AB_2686882" "unprognostic (2.42e-2)" "unprognostic (6.60e-2)" "unprognostic (3.85e-3)" "unprognostic (9.46e-3)" "unprognostic (8.77e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.03e-6)" "unprognostic (7.59e-2)" "unprognostic (3.00e-3)" "unprognostic (5.03e-3)" "unprognostic (4.41e-3)" "unprognostic (2.34e-3)" "unprognostic (5.81e-3)" "unprognostic (8.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (2.41e-2)" 11.5 11.0 2.6 16.9 3.4 16.1 18.7 3.4 4.3 12.5 3.7 22.6 16.3 9.6 17.4 23.1 27.1 11.3 8.4 2.4 2.9 18.0 11.5 12.4 16.3 5.6 7.4 6.7 16.1 18.6 8.7 19.3 4.5 14.9 22.5 8.6 16.8 16.1 12.1 13.2 21.6 11.7 2.7 11.2 16.1 15.5 3.2 12.6 18.5 5.6 17.9 16.8 11.7 5.6 51.3 22.5 18.0 13.0 10.7 18.4 74.4 38.9 12.9 38.6 29.7 27.8 56.5 42.1 43.3 18.3 6.5 35.8 29.1 51.9 46.0 52.3 49.7 44.1 29.5 26.7 2.8 107.7 38.9 16.4 38.9 32.3 20.3 14.7 28.3 45.6 64.1 35.8 41.4 31.3 35.1 54.9 47.3 75.3 53.4 33.4 54.4 58.0 50.3 40.6 34.9 23.5 37.0 47.5 25.7 42.4 33.5 52.6 23.2 20.4 33.5 31.2 45.6 25.3 48.7 45.1 20.5 63.9 26.0 51.6 32.8 85.2 18.8 39.7 21.6 22.0 22.1 22.5 40.9 17.7 18.8 21.4 64.4 27.2 38.0 54.3 33.8 22.6 2.6 3.4 3.4 4.3 2.4 2.9 5.6 7.4 4.5 2.7 3.2 5.6 9.2 9.6 13.1 0.0 18.7 10.6 15.7 31.8 22.2 0.7 25.9 14.1 7.9 20.0 37.5 27.6 0.0 106.0 26.7 35.1 64.6 27.0 68.3 84.1 11.4 11.8 9.6 38.7 0.0 27.2 86.2 9.5 21.9 17.9 26.1 9.3 8.9 15.3 21.0 10.1 0.0 25.2 26.4 15.0 14.8 25.2 7.2 20.5 19.6 0.0 31.0 5.5 18.6 0.0 0.0 29.7 40.2 9.1 69.6 18.2 31.2 50.3 142.2 5.0 6.6 6.7 14.8 29.9 64.5 53.4 17.8 88.1 19.3 14.0 31.5 22.4 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYOCD MYCD ENSG00000141052 Myocardin Q8IZQ8 17 12665890-12768949 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.2" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 47.3;Endometrial stromal cells: 48.5;Peritubular cells: 100.8;Sertoli cells: 26.3;Smooth muscle cells: 32.9" "Cancer enhanced" "Detected in some" "stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 6.5;BJ hTERT+: 6.4;HBF TERT88: 10.4;hTEC/SVTERT24-B: 11.7;REH: 8.4;SuSa: 12.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "CAB046485, HPA071528, HPA072582" Approved Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB046485: AB_10600720, HPA071528: , HPA072582: " "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (1.90e-1)" "unprognostic (3.79e-2)" "unprognostic (5.33e-2)" "unprognostic (2.15e-4)" "unprognostic (2.71e-2)" "unprognostic (1.61e-2)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (4.83e-2)" "unprognostic (1.01e-4)" "unprognostic (2.88e-2)" "unprognostic (1.07e-1)" "unprognostic (5.45e-2)" "unprognostic (1.91e-2)" 3.2 1.0 0.4 4.3 0.7 0.0 1.2 0.3 0.8 9.4 1.6 24.2 2.6 13.0 2.4 13.1 8.5 4.6 14.2 0.4 0.4 0.7 0.2 2.7 0.1 0.5 0.5 4.4 0.3 0.1 0.2 3.4 0.8 8.8 4.9 0.0 0.2 20.7 0.5 1.3 5.1 15.8 0.5 0.6 6.1 2.1 0.8 0.1 0.7 0.8 0.1 17.2 4.4 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 6.4 2.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 1.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 12.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.8 0.4 0.4 0.5 0.5 0.8 0.5 0.8 0.4 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 47.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 2.0 48.5 1.2 7.8 0.0 1.2 0.2 0.1 3.6 0.0 1.0 0.0 8.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 1.0 0.5 0.6 0.2 0.0 9.4 0.0 0.0 0.0 1.0 0.3 0.0 0.0 100.8 0.0 0.1 0.0 0.1 0.0 0.0 26.3 0.2 32.9 0.3 0.8 0.1 0.9 0.5 0.4 6.0 0.0 0.1 MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 89.8;lymphoid tissue: 272.2" "Cell type enriched" "Detected in many" 6 "Plasma cells: 4000.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "memory B-cell: 160.4;plasmacytoid DC: 569.3" "Group enriched" "Detected in many" 116 "B-cells: 160.4;dendritic cells: 569.3" "Group enriched" "Detected in some" 5 "Karpas-707: 581.5;RPMI-8226: 2193.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA 350000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA043745: AB_10960359, HPA052694: AB_2681919" "unprognostic (4.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.23e-2)" "prognostic favorable (7.27e-4)" "unprognostic (2.21e-2)" "prognostic favorable (4.60e-5)" "unprognostic (6.57e-2)" "unprognostic (1.35e-1)" "unprognostic (6.45e-3)" "unprognostic (7.10e-3)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.15e-8)" "unprognostic (7.22e-2)" "unprognostic (3.14e-1)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" 4.4 9.1 0.0 87.4 0.1 33.0 21.0 0.0 0.7 18.3 0.2 70.1 89.8 1.8 0.4 10.1 5.7 14.3 2.3 0.0 0.0 5.9 5.8 15.9 123.2 0.1 0.0 4.9 1.3 0.0 0.7 0.0 0.1 5.1 39.9 0.0 56.7 4.9 0.1 0.4 47.8 2.1 0.4 272.2 66.6 2.4 0.1 147.3 9.1 0.0 117.8 58.7 3.6 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 256.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 144.6 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 128.5 0.5 581.5 0.0 0.0 227.8 2.2 0.0 0.0 0.0 90.1 0.3 2193.9 0.0 0.0 0.3 0.8 0.0 11.4 0.0 0.0 3.1 0.1 0.6 0.0 1.8 0.1 0.0 262.0 16.7 223.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.1 3.0 160.4 0.6 1.1 0.5 75.6 0.1 0.2 3.1 2.7 0.0 569.3 0.2 26.1 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.3 0.4 6.4 10.1 0.0 665.7 2.5 1.3 0.1 0.0 0.0 3.7 3.2 1.1 4.3 2.0 0.0 0.0 0.1 235.0 0.9 0.0 0.1 0.1 1.8 0.4 2.0 1.2 49.3 0.0 0.0 0.1 2.0 6.1 0.4 2.5 0.1 11.4 14.0 0.1 0.0 0.0 1.1 0.0 7.1 3.4 1.1 0.0 4.7 540.7 0.0 1.0 0.0 4.1 0.0 0.0 0.1 0.4 0.0 4000.1 3.0 1.2 1.9 1.2 0.0 0.0 1.7 2.1 0.1 0.1 0.4 2.4 2.2 100.7 0.5 9.7 0.4 NAP1L2 "BPX, MGC26243" ENSG00000186462 "Nucleosome assembly protein 1 like 2" Q9ULW6 X 73212299-73214851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.4;Excitatory neurons: 34.3;Horizontal cells: 18.5;Inhibitory neurons: 33.7" "Cancer enhanced" "Detected in many" "prostate cancer: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 16.6;Karpas-707: 14.1;NTERA-2: 18.1;U-2197: 14.6;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054050, HPA057065" Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA054050: AB_2682357, HPA057065: AB_2797258" "unprognostic (1.12e-1)" "unprognostic (6.64e-5)" "unprognostic (4.22e-2)" "unprognostic (9.64e-4)" "unprognostic (1.78e-1)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (8.51e-3)" "unprognostic (1.76e-2)" "unprognostic (2.66e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.53e-2)" "unprognostic (1.54e-2)" "unprognostic (6.95e-4)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.45e-2)" 2.1 6.0 22.7 2.2 24.4 0.5 3.1 28.4 60.4 4.2 4.6 3.4 0.9 5.1 8.2 2.6 4.0 2.3 7.9 28.8 27.0 8.3 1.0 2.3 3.2 18.5 15.4 8.9 2.5 12.1 14.5 0.0 17.9 11.0 2.9 19.1 3.2 5.8 1.3 5.2 2.2 4.7 12.1 4.2 2.2 2.1 15.7 1.7 8.5 2.9 1.6 2.9 2.6 25.7 0.0 4.8 0.1 9.4 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.3 0.0 16.6 0.0 8.9 1.0 3.4 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.8 0.4 1.3 0.2 2.4 0.1 0.3 6.6 0.4 14.1 0.0 1.7 5.9 0.0 18.1 0.0 8.4 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 1.1 0.0 3.5 1.8 0.0 0.1 0.0 10.3 14.6 1.2 6.6 31.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.3 1.2 0.8 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.0 1.0 0.5 22.7 24.4 28.4 60.4 28.8 27.0 18.5 15.4 17.9 12.1 15.7 25.7 1.0 0.0 3.0 8.5 0.9 6.4 6.2 1.0 8.0 24.4 0.7 2.9 11.1 2.8 0.8 12.9 0.0 0.0 2.9 1.8 13.7 1.1 0.0 0.0 0.2 3.1 7.2 0.0 34.3 0.2 0.0 4.1 1.1 0.1 4.5 0.2 3.6 0.7 0.1 18.5 33.7 0.4 0.0 0.3 0.0 0.4 0.3 0.1 0.0 9.4 0.0 13.7 0.0 9.5 9.1 0.8 0.5 0.4 1.9 3.3 0.0 3.3 0.0 9.9 0.0 5.5 4.0 0.2 0.1 2.6 3.0 0.0 3.5 0.2 0.5 1.0 NAP1L4 NAP2 ENSG00000205531 "Nucleosome assembly protein 1 like 4" Q99733 11 2944431-2992377 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011567 Approved Supported Nucleoplasm NA NA 3100000 "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB011567: AB_776638" "unprognostic (1.61e-1)" "prognostic favorable (9.77e-4)" "unprognostic (8.99e-2)" "unprognostic (9.64e-3)" "unprognostic (2.96e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.80e-1)" "unprognostic (6.44e-2)" "unprognostic (1.77e-1)" "unprognostic (6.73e-2)" "unprognostic (2.31e-1)" "unprognostic (6.10e-3)" "unprognostic (1.19e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.55e-4)" "unprognostic (1.54e-1)" 39.6 43.5 44.3 36.1 59.2 50.3 41.3 53.0 178.1 46.7 70.3 60.3 20.1 45.4 17.3 79.6 41.2 32.5 111.4 41.3 52.1 63.7 56.2 40.5 65.7 57.2 53.8 42.9 38.0 63.5 61.4 36.8 60.2 51.9 34.2 38.6 66.4 32.1 146.1 49.0 53.8 39.1 52.2 59.0 56.6 87.4 56.4 78.8 44.6 110.7 75.8 61.9 52.1 72.2 82.8 59.9 81.7 65.7 83.9 92.4 37.7 159.8 104.1 145.4 132.5 129.7 208.4 149.5 95.3 98.0 15.1 140.0 21.9 136.3 166.8 159.2 57.5 106.7 151.4 168.2 57.7 93.0 110.5 77.8 65.1 78.6 59.1 12.0 88.9 77.6 139.3 150.7 128.0 74.5 206.4 4.2 199.8 98.9 75.2 101.4 98.1 117.0 12.2 131.7 121.4 104.3 80.5 118.1 78.3 82.5 7.3 7.4 67.8 112.5 104.4 152.4 13.8 79.3 136.5 201.5 8.4 66.0 75.3 67.5 22.9 32.6 42.3 24.0 39.9 24.7 51.9 53.0 27.2 28.4 45.7 52.1 14.5 57.6 30.4 25.0 70.5 48.0 44.3 59.2 53.0 178.1 41.3 52.1 57.2 53.8 60.2 52.2 56.4 72.2 53.6 44.8 49.8 56.2 64.3 70.1 67.4 76.9 83.1 80.4 54.6 48.3 200.4 42.9 69.0 75.4 45.9 103.8 99.4 37.2 97.8 78.7 97.0 107.7 65.9 55.4 45.4 168.7 36.9 50.4 109.2 56.6 54.0 91.1 74.6 100.6 43.5 50.0 47.3 65.6 56.6 41.4 67.1 30.8 44.7 142.6 48.1 49.7 35.6 38.4 65.3 67.5 95.8 60.8 125.3 74.1 26.8 50.0 100.7 76.1 39.8 76.9 92.6 68.1 46.0 58.8 64.7 166.1 129.0 102.3 66.9 91.3 123.8 79.7 55.1 83.7 NCAPG "CAP-G, FLJ12450, hCAP-G, YCG1" ENSG00000109805 "Non-SMC condensin I complex subunit G" Q9BPX3 4 17810979-17844865 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 59.3;Extravillous trophoblasts: 26.6;Plasma cells: 20.4;Spermatocytes: 63.7;Spermatogonia: 24.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in single" "white matter: 1.6" "Low region specificity" "Detected in all" HPA039613 Uncertain NA Yes 9500 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA039613: AB_10805481" "unprognostic (5.23e-2)" "unprognostic (3.37e-1)" "unprognostic (1.59e-3)" "prognostic unfavorable (8.28e-4)" "unprognostic (4.22e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (1.18e-3)" "unprognostic (1.63e-2)" "unprognostic (6.70e-2)" "prognostic unfavorable (7.65e-5)" "unprognostic (3.44e-2)" "unprognostic (0.00e+0)" "unprognostic (1.94e-2)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (2.07e-1)" 0.7 0.5 0.1 4.1 0.1 13.9 0.9 0.5 0.1 0.7 0.2 3.0 3.8 0.6 0.0 3.5 0.2 0.9 0.3 0.0 0.2 0.2 0.7 0.6 8.7 0.6 1.2 0.2 0.2 0.1 0.1 3.0 0.7 0.3 2.4 0.3 0.7 0.0 0.2 3.5 3.2 1.0 1.2 2.1 1.9 5.6 0.3 15.8 0.3 0.1 8.7 1.2 1.0 0.2 45.1 28.3 63.8 42.2 4.0 7.8 23.1 56.8 22.2 55.0 55.8 36.3 26.8 66.8 11.3 16.0 47.6 19.9 54.5 22.1 74.8 30.5 27.0 53.6 37.3 29.8 0.2 38.4 20.3 1.5 1.5 40.7 18.6 8.8 27.9 28.9 53.1 74.1 55.0 13.4 44.1 36.9 32.8 26.1 27.9 42.8 57.4 28.0 16.6 13.9 50.0 29.7 51.2 10.9 15.7 27.2 25.6 21.3 23.2 52.5 23.6 30.0 78.9 23.2 23.3 56.1 21.7 39.1 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.6 0.4 0.1 0.1 0.5 0.1 0.0 0.2 0.6 1.2 0.7 1.2 0.3 0.2 0.3 0.0 1.1 0.0 3.3 2.4 0.6 1.9 1.2 0.2 0.6 0.6 0.2 0.0 0.8 0.0 0.0 11.7 1.6 2.9 0.0 0.1 15.8 0.9 1.9 1.7 1.8 59.3 0.2 0.0 26.6 3.8 7.1 2.3 1.3 14.2 2.2 0.5 9.5 0.0 0.4 3.1 2.0 2.6 2.9 9.5 0.6 3.7 1.8 1.0 0.7 0.3 3.1 0.5 0.5 0.2 0.1 0.0 20.4 0.4 0.2 0.0 0.0 0.2 0.0 0.2 4.3 63.7 24.3 11.0 1.1 2.2 3.7 0.7 5.6 1.3 NCOA6 "AIB3, ASC2, KIAA0181, NRC, PRIP, RAP250, TRBP" ENSG00000198646 "Nuclear receptor coactivator 6" Q14686 20 34689097-34825651 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 130.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004198, HPA050211" Supported Supported Nucleoplasm NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004198: AB_1078228, HPA050211: AB_2681052" "unprognostic (2.48e-1)" "unprognostic (4.81e-2)" "unprognostic (1.72e-1)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (1.10e-1)" "prognostic unfavorable (4.65e-4)" "unprognostic (2.05e-1)" "unprognostic (2.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-1)" "prognostic favorable (8.78e-5)" "unprognostic (9.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.42e-2)" 10.2 9.0 5.2 9.1 6.7 14.0 9.2 12.7 12.4 10.8 4.8 12.9 13.2 10.7 12.2 11.7 11.3 8.8 9.2 6.1 8.2 9.9 8.4 10.4 8.9 6.3 4.6 11.6 12.6 22.0 10.0 13.5 4.6 9.8 14.5 26.7 12.9 11.3 12.7 13.5 12.0 13.2 2.3 9.4 11.4 18.8 7.4 18.1 13.8 13.1 10.3 10.4 10.5 9.6 25.2 14.7 32.6 19.7 17.5 19.4 21.3 12.0 15.3 21.1 16.9 37.9 17.2 17.7 12.9 21.5 25.8 30.0 29.3 20.2 23.9 9.0 13.2 41.6 16.7 22.4 19.3 23.5 29.4 14.8 36.5 19.8 24.5 14.6 20.2 20.1 21.5 23.7 17.7 16.3 37.5 14.8 6.7 21.0 21.1 24.9 39.3 15.9 15.6 16.6 27.2 18.5 22.0 52.5 20.5 15.0 22.2 18.5 20.0 34.1 20.7 25.6 20.2 26.9 24.3 20.0 22.5 13.5 15.5 1.1 0.6 2.5 0.9 0.5 0.8 1.0 0.8 0.8 1.1 0.8 0.7 0.5 1.5 0.7 0.7 1.0 0.5 0.5 5.2 6.7 12.7 12.4 6.1 8.2 6.3 4.6 4.6 2.3 7.4 9.6 17.3 25.6 16.0 54.9 11.0 17.0 9.1 10.6 13.6 28.8 14.3 10.9 20.1 18.6 11.6 16.5 29.2 13.0 12.2 31.9 5.9 12.5 23.5 16.4 21.3 14.0 10.8 13.3 50.9 12.4 12.1 14.5 15.8 23.3 6.3 18.5 13.9 12.1 10.8 33.7 58.8 17.4 20.3 12.2 10.3 17.3 18.0 13.0 10.6 45.9 17.6 11.5 13.4 54.3 130.4 15.4 12.4 13.5 14.2 16.9 20.3 9.3 17.5 29.8 26.3 16.6 16.9 25.6 27.1 19.2 20.9 15.9 13.1 13.6 17.6 14.6 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NDUFA5 "B13, CI-13kB, CI-13KD-B, NUFM, UQOR13" ENSG00000128609 "NADH:ubiquinone oxidoreductase subunit A5" Q16718 7 123536997-123557904 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 403.3" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 717.3;Distal tubular cells: 1070.2;Proximal tubular cells: 667.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043175 Supported NA NA 81000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043175: AB_10793992" "prognostic favorable (8.47e-5)" "unprognostic (4.00e-2)" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "unprognostic (4.90e-2)" "unprognostic (3.26e-1)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.81e-1)" "unprognostic (2.14e-2)" "unprognostic (1.37e-1)" "unprognostic (9.20e-2)" "prognostic favorable (3.99e-9)" "unprognostic (3.39e-1)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (2.73e-3)" 55.2 129.2 94.7 34.1 99.9 34.8 68.8 94.2 130.1 51.3 93.4 78.5 77.6 47.5 71.5 51.0 51.8 47.0 215.7 100.5 108.4 175.3 114.9 44.4 40.0 92.4 97.6 42.2 41.2 170.1 58.3 39.7 98.5 72.8 73.3 127.1 75.6 63.1 285.1 27.2 72.7 46.9 92.6 35.4 77.4 38.3 94.4 52.8 136.6 403.3 42.5 57.8 33.5 91.6 65.9 41.8 76.3 76.6 64.5 58.6 39.5 57.4 63.1 46.8 61.1 47.1 58.2 108.6 54.8 58.8 91.0 60.7 83.9 75.2 74.3 89.6 71.7 68.8 85.9 78.1 62.7 140.5 56.4 58.6 65.9 45.3 47.3 84.1 68.4 75.4 213.9 104.9 84.4 45.5 127.3 162.1 100.3 154.3 107.0 69.2 75.0 146.6 129.5 63.7 144.9 86.3 76.1 286.2 90.3 102.5 65.6 104.7 53.1 58.9 31.7 262.0 88.5 111.2 109.4 116.4 112.7 106.2 75.7 57.8 26.2 31.5 38.2 48.7 55.4 53.6 48.6 44.9 37.1 41.6 52.5 54.0 9.2 52.7 54.8 40.0 55.8 60.4 94.7 99.9 94.2 130.1 100.5 108.4 92.4 97.6 98.5 92.6 94.4 91.6 99.2 102.5 100.4 38.2 108.7 112.5 146.2 280.3 74.6 183.6 113.0 100.8 717.3 102.9 160.6 165.5 83.4 160.6 105.6 119.0 1070.2 132.2 359.6 123.4 91.1 91.8 138.0 91.1 65.2 89.6 156.8 110.5 108.6 128.6 88.7 59.2 66.0 170.6 109.6 127.9 48.5 168.6 295.0 67.2 92.5 77.5 90.1 94.9 202.7 19.7 65.7 264.6 77.2 32.2 29.2 86.2 130.9 112.1 82.0 107.1 210.2 667.6 158.6 214.7 118.3 97.4 133.7 179.0 99.0 94.7 110.2 158.4 102.3 116.9 172.2 147.0 NDUFAF3 "2P1, C3orf60, DKFZP564J0123, E3-3, MGC10527" ENSG00000178057 "NADH:ubiquinone oxidoreductase complex assembly factor 3" Q9BU61 3 49020459-49023495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 329.8" "Group enriched" "Detected in all" 4 "Distal tubular cells: 475.4;Early spermatids: 1124.6;Late spermatids: 1303.4;Proximal tubular cells: 658.1;Spermatocytes: 913.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035376, HPA035377" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA035376: AB_2674597, HPA035377: AB_10673219" "unprognostic (2.90e-2)" "unprognostic (2.72e-2)" "unprognostic (6.88e-2)" "unprognostic (3.03e-2)" "unprognostic (3.57e-2)" "unprognostic (2.61e-1)" "unprognostic (6.28e-3)" "unprognostic (4.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.64e-2)" "unprognostic (8.62e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.86e-5)" "unprognostic (7.97e-2)" "unprognostic (1.73e-1)" "unprognostic (8.02e-2)" "unprognostic (1.60e-1)" 69.0 121.9 112.1 36.4 119.9 51.7 60.7 124.3 123.6 58.4 117.3 43.5 34.9 58.6 47.7 48.5 61.7 32.3 166.0 109.4 117.8 88.6 85.2 52.2 45.3 121.2 116.5 59.4 48.8 84.1 99.0 29.9 120.2 57.2 27.0 26.2 70.7 51.5 127.0 33.1 41.4 30.7 120.5 53.9 49.8 329.8 118.0 52.0 71.2 99.6 37.7 51.1 45.7 126.8 47.7 68.4 60.6 59.9 78.5 66.6 35.0 59.6 57.5 82.8 64.5 98.9 75.1 55.1 68.5 92.1 113.4 34.9 43.3 95.4 29.6 72.9 76.8 109.5 129.9 124.8 110.4 92.2 50.8 68.5 72.5 116.6 85.8 98.9 73.0 169.4 31.4 136.0 90.8 73.9 134.1 46.5 20.1 78.1 183.0 41.1 24.3 169.3 136.7 97.4 52.9 61.6 55.0 115.1 59.1 27.3 66.5 177.6 64.4 76.4 52.0 108.0 100.1 110.8 79.3 86.6 93.2 48.4 121.8 144.3 164.6 143.9 157.6 175.3 168.4 244.1 172.6 160.6 144.9 234.0 223.3 170.2 51.8 154.9 201.2 297.8 180.5 250.4 112.1 119.9 124.3 123.6 109.4 117.8 121.2 116.5 120.2 120.5 118.0 126.8 117.4 93.0 95.2 7.2 95.3 53.3 143.7 113.6 66.0 60.4 119.4 125.5 198.0 104.4 109.6 150.8 2.1 135.2 81.9 124.6 475.4 171.7 1124.6 123.4 81.8 104.3 132.0 118.2 7.2 155.7 128.0 121.2 50.0 58.2 117.3 73.1 114.9 150.6 217.8 69.0 8.3 118.1 103.7 114.1 73.8 1303.4 170.2 129.5 136.9 11.2 149.6 171.5 103.0 6.6 19.6 139.5 148.0 120.7 151.1 175.5 176.9 658.1 199.2 52.8 72.3 87.5 106.4 913.0 88.6 108.4 54.8 106.9 91.2 105.6 109.4 154.9 NDUFB5 "CI-SGDH, MGC12314, SGDH" ENSG00000136521 "NADH:ubiquinone oxidoreductase subunit B5" O43674 3 179604690-179627647 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 241.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005640 Enhanced Supported Nucleoplasm,Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA005640: AB_1079461" "unprognostic (6.76e-2)" "unprognostic (1.09e-2)" "unprognostic (6.33e-2)" "unprognostic (3.51e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-3)" "unprognostic (1.33e-2)" "unprognostic (1.63e-1)" "unprognostic (4.46e-2)" "unprognostic (5.96e-3)" "unprognostic (4.83e-2)" "unprognostic (7.11e-2)" "prognostic favorable (3.32e-5)" "unprognostic (3.05e-1)" "unprognostic (1.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" 61.0 88.4 35.6 29.0 38.5 19.5 47.8 39.4 57.3 37.7 52.8 64.0 75.1 30.2 15.6 56.7 33.4 28.8 217.0 38.4 40.0 93.5 74.0 34.4 36.1 37.1 36.6 41.9 52.3 66.6 40.2 27.0 37.4 32.6 36.1 22.7 43.7 20.2 241.4 43.6 57.0 22.3 35.4 46.3 63.8 42.2 39.8 31.4 41.6 166.9 24.8 46.2 41.5 38.9 96.5 23.2 51.2 66.8 52.3 66.0 75.6 58.5 42.0 48.1 50.7 79.8 53.4 72.7 193.4 32.7 119.5 89.9 48.9 47.4 38.9 182.5 43.1 90.4 31.2 44.8 52.3 97.9 64.0 64.9 60.7 31.2 51.0 61.0 62.8 62.1 71.2 98.7 51.8 68.8 55.8 60.5 80.2 138.7 80.8 64.2 63.3 205.1 82.5 46.8 41.1 62.4 34.9 169.9 126.7 36.2 265.9 151.2 64.5 46.6 47.8 61.7 139.9 158.0 193.6 122.5 75.8 91.7 67.9 94.6 104.5 49.9 43.8 127.8 64.5 90.2 60.0 51.6 145.5 67.2 59.8 62.9 18.9 48.1 154.8 81.0 84.0 105.6 35.6 38.5 39.4 57.3 38.4 40.0 37.1 36.6 37.4 35.4 39.8 38.9 113.6 48.1 48.5 17.3 90.2 85.1 115.2 374.4 73.4 45.9 121.0 138.6 362.3 88.6 164.3 88.3 33.3 234.0 54.5 115.9 508.7 132.5 162.6 118.4 79.0 89.2 117.5 75.3 16.1 105.7 150.0 87.1 77.5 62.9 93.8 120.1 105.7 118.3 253.5 40.4 22.6 196.0 266.5 261.3 133.0 28.9 81.1 133.6 135.2 15.9 180.0 107.2 70.0 19.6 25.8 81.5 163.4 70.0 75.0 89.8 293.5 462.8 157.9 73.4 72.3 87.1 98.5 265.7 128.3 105.9 88.7 230.0 72.9 257.4 268.8 163.4 NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 583.9;Distal tubular cells: 534.1;Early spermatids: 889.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044001, HPA053334" Supported Enhanced Mitochondria No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "HPA044001: AB_10959448, HPA053334: AB_2682116" "unprognostic (4.09e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.81e-2)" "unprognostic (1.53e-2)" "unprognostic (1.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.10e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-3)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "prognostic favorable (7.47e-10)" "unprognostic (2.70e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" 38.6 50.8 42.7 30.7 45.3 31.0 35.9 47.1 48.1 34.1 42.8 41.8 44.6 38.1 26.8 43.8 36.0 17.6 144.9 44.5 46.5 73.6 66.7 30.5 26.9 44.5 42.9 29.7 31.0 41.8 40.3 22.5 44.6 28.5 29.1 30.7 37.0 22.0 168.0 28.2 43.6 26.7 45.9 28.8 43.5 53.5 44.3 28.7 33.2 101.8 24.5 34.1 33.4 47.1 106.4 63.7 69.6 80.1 46.7 43.0 44.5 69.5 56.5 62.8 68.8 62.8 46.5 78.4 70.5 48.2 65.1 58.8 66.5 76.8 47.0 108.6 106.0 187.2 88.8 65.9 45.2 94.4 46.3 44.8 36.7 56.8 42.9 47.5 57.6 118.4 61.0 86.1 71.9 61.2 128.1 221.2 73.6 90.7 140.1 86.7 58.4 73.1 72.0 39.3 69.7 78.4 80.2 91.1 50.7 52.0 86.3 72.0 51.4 67.9 103.8 75.7 103.8 38.0 77.0 131.5 113.7 65.6 32.7 126.3 97.6 136.1 76.9 94.3 74.5 106.0 81.4 80.0 108.8 89.0 82.3 87.4 302.1 91.9 116.3 152.7 112.4 110.2 42.7 45.3 47.1 48.1 44.5 46.5 44.5 42.9 44.6 45.9 44.3 47.1 69.5 125.0 111.6 15.3 76.2 94.2 106.2 222.9 90.0 44.1 64.6 72.6 583.9 101.5 141.4 108.5 6.2 191.8 69.4 115.8 534.1 172.5 889.5 106.9 86.1 101.0 64.6 196.7 21.8 166.7 143.0 109.5 83.6 86.4 90.5 64.3 74.3 182.2 160.8 18.5 23.8 152.5 209.5 55.0 96.4 146.9 91.6 78.4 160.1 3.7 108.6 115.3 90.6 18.1 21.3 144.4 124.9 89.9 165.7 80.0 201.0 520.3 152.3 56.5 105.2 94.8 151.3 182.0 125.9 139.7 96.7 104.1 81.0 95.6 167.3 103.8 NDUFB7 "B18, CI-B18, MGC2480" ENSG00000099795 "NADH:ubiquinone oxidoreductase subunit B7" P17568 19 14566078-14572066 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002817 Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA002817: AB_1079462" "unprognostic (2.80e-2)" "prognostic favorable (3.54e-4)" "unprognostic (2.03e-1)" "unprognostic (4.09e-2)" "unprognostic (4.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-3)" "unprognostic (2.07e-1)" "unprognostic (1.87e-2)" "unprognostic (2.02e-2)" "unprognostic (4.14e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.40e-1)" "unprognostic (1.69e-1)" "unprognostic (1.59e-1)" "unprognostic (9.25e-3)" 203.1 216.1 209.9 66.1 218.4 103.7 188.8 232.4 325.4 153.6 216.5 256.3 124.6 169.4 51.1 230.7 152.3 57.7 695.8 204.8 222.5 291.7 335.7 127.8 70.4 222.2 221.3 137.3 213.5 143.2 182.8 61.6 218.9 171.0 55.9 28.6 198.7 93.2 709.4 189.4 163.2 50.6 213.2 150.0 231.9 132.8 230.2 50.6 189.7 266.9 39.5 167.3 161.2 222.6 242.1 237.4 95.0 203.1 80.4 80.5 167.4 110.1 120.6 200.0 189.2 317.9 130.2 109.4 322.0 102.9 87.5 185.0 62.6 241.1 26.7 170.1 320.8 212.2 380.9 334.6 142.1 138.7 141.5 131.7 196.6 105.7 49.6 56.1 161.7 194.9 132.9 194.8 94.2 452.7 227.0 308.0 242.4 228.1 773.2 174.3 112.8 264.6 143.0 253.3 204.4 217.6 114.9 265.6 303.4 24.6 175.0 245.1 122.0 253.5 123.2 324.4 207.0 264.4 295.5 144.1 243.7 267.8 174.5 355.6 414.5 140.4 432.9 395.5 403.8 368.6 291.4 368.9 415.4 327.7 241.3 315.5 119.4 422.4 389.5 460.4 373.3 562.3 209.9 218.4 232.4 325.4 204.8 222.5 222.2 221.3 218.9 213.2 230.2 222.6 196.4 76.9 95.9 19.9 155.6 133.4 177.9 358.5 126.9 117.4 285.4 363.9 670.4 245.9 214.2 259.3 56.3 359.7 155.5 937.3 1154.3 324.9 81.8 162.8 133.9 163.5 332.1 152.9 7.4 455.3 330.5 185.2 194.7 152.1 102.2 197.4 203.1 589.1 377.5 72.3 11.4 639.3 299.1 237.9 158.0 252.0 207.5 173.9 378.8 10.3 327.3 236.4 365.6 8.5 25.5 367.9 720.8 200.1 197.5 175.4 916.4 1041.9 193.1 152.4 236.7 193.6 330.8 133.7 252.1 235.7 161.2 225.6 138.6 197.5 631.6 220.1 NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 83.5;skeletal muscle: 268.3;tongue: 158.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1840.3;Distal tubular cells: 1136.7;Proximal tubular cells: 1449.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044556, HPA062427" Enhanced Approved Mitochondria No No "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA044556: AB_10794402, HPA062427: " "unprognostic (6.07e-2)" "unprognostic (4.61e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.23e-5)" "unprognostic (7.11e-2)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.62e-2)" "unprognostic (3.60e-2)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.96e-4)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-1)" "prognostic favorable (7.25e-4)" 9.5 15.3 19.9 8.0 20.4 9.1 11.0 22.4 28.6 7.4 21.3 18.6 23.8 8.1 14.3 10.5 10.5 5.4 83.5 19.6 20.8 26.7 24.1 8.8 10.1 20.3 21.0 10.0 14.8 22.9 15.8 5.9 21.6 9.7 19.0 23.5 18.9 14.4 268.3 13.2 18.6 7.4 19.5 10.4 17.0 12.7 20.5 8.6 14.8 158.5 11.0 8.6 7.9 22.4 21.4 5.9 19.2 30.8 17.7 22.7 20.5 20.1 13.1 11.1 10.4 13.1 23.7 7.7 7.7 15.5 14.9 10.5 38.6 18.2 15.0 13.0 13.5 11.9 13.5 23.0 18.1 11.2 10.1 24.5 18.2 14.4 21.6 16.8 17.5 17.8 25.3 33.8 11.0 17.8 17.8 32.1 16.3 44.1 11.7 14.9 10.6 52.6 24.6 14.2 14.6 14.7 13.8 23.2 10.5 15.6 23.7 23.2 8.1 24.2 6.4 13.0 13.5 23.2 49.5 18.5 18.9 26.7 13.8 26.2 10.1 13.1 8.5 10.3 11.6 7.1 11.7 11.5 8.9 15.9 10.5 11.4 3.0 10.1 14.2 16.2 18.2 10.8 19.9 20.4 22.4 28.6 19.6 20.8 20.3 21.0 21.6 19.5 20.5 22.4 201.8 89.8 145.7 15.7 95.8 140.2 173.3 402.7 185.0 120.4 240.3 349.6 1840.3 221.6 240.1 439.6 33.3 147.4 71.7 343.0 1136.7 270.3 409.9 333.5 115.5 162.7 221.4 175.2 10.9 336.9 166.2 176.9 158.0 196.8 73.3 151.2 133.5 432.9 225.1 119.5 14.3 340.5 276.7 102.0 65.7 70.9 169.3 115.6 266.8 6.5 185.5 446.6 79.3 8.0 13.3 265.3 355.8 206.5 155.6 173.7 471.7 1449.6 297.1 139.1 98.6 159.3 184.4 439.0 197.4 290.1 179.3 118.1 83.5 224.7 343.7 176.0 NDUFC2 "B14.5b, HLC-1" ENSG00000151366 "NADH:ubiquinone oxidoreductase subunit C2" O95298 11 78068297-78079862 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038873, HPA056195" Approved Supported Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA038873: AB_10673480, HPA056195: AB_2683063" "unprognostic (7.32e-2)" "unprognostic (5.91e-3)" "unprognostic (4.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.94e-1)" "unprognostic (8.97e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-3)" "unprognostic (4.75e-3)" "unprognostic (3.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "prognostic favorable (5.00e-5)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (3.61e-3)" 202.3 278.0 118.8 84.5 126.1 126.1 143.0 128.7 150.7 103.0 125.6 143.6 218.4 125.3 68.4 142.6 120.2 108.6 240.7 129.0 145.8 151.1 286.8 100.0 109.1 121.6 117.1 96.2 168.8 186.1 133.5 74.8 124.2 88.7 66.1 59.8 275.1 83.2 487.6 121.9 194.3 63.6 136.8 96.2 130.0 103.0 126.1 73.5 207.0 254.0 62.8 97.1 100.1 136.3 287.6 342.2 183.3 118.8 168.3 105.6 227.2 335.7 190.9 252.4 179.9 910.4 311.8 166.3 583.3 155.8 210.2 293.1 136.1 190.9 99.5 318.8 386.7 183.8 337.4 727.9 270.9 409.7 164.2 147.9 177.8 195.6 75.2 156.0 172.9 158.8 365.3 278.4 137.9 478.7 254.5 722.4 212.4 670.4 415.6 224.5 352.5 570.5 196.4 420.7 261.2 229.0 235.0 499.5 182.3 158.8 391.4 328.2 241.0 256.4 314.9 611.8 297.9 251.5 541.9 400.4 146.4 236.6 251.0 374.5 337.6 354.0 150.1 293.0 138.3 230.8 172.4 163.4 363.5 212.1 144.5 159.8 102.2 225.4 243.0 290.4 202.7 410.9 118.8 126.1 128.7 150.7 129.0 145.8 121.6 117.1 124.2 136.8 126.1 136.3 256.6 166.7 194.7 0.0 106.4 95.5 166.1 443.7 40.5 145.8 346.2 414.0 240.9 243.1 288.2 391.8 66.7 408.8 166.4 206.3 305.2 395.6 311.8 413.8 129.3 183.7 167.9 106.5 0.0 431.5 392.8 165.7 43.3 241.7 153.2 158.1 184.9 856.9 346.2 90.9 0.0 317.9 429.3 174.5 110.7 84.7 215.6 129.4 245.5 0.0 246.7 310.0 175.1 0.0 0.0 456.5 329.1 201.6 102.5 239.0 461.8 454.6 300.0 131.6 236.7 154.5 222.7 384.4 162.1 67.5 114.4 387.1 109.9 226.3 373.2 215.6 NEIL3 "FLJ10858, FPG2, hFPG2, hNEI3, ZGRF3" ENSG00000109674 "Nei like DNA glycosylase 3" Q8TAT5 4 177309874-177362936 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.6;lymphoid tissue: 23.6" "Cell type enhanced" "Detected in some" "Erythroid cells: 14.7;Granulosa cells: 4.8;Plasma cells: 6.1;Squamous epithelial cells: 4.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 72.1;HL-60: 79.1;Karpas-707: 99.1;MOLT-4: 80.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" HPA065761 Enhanced Nucleoplasm NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA065761: AB_2685555" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (5.45e-4)" "unprognostic (4.91e-2)" "unprognostic (2.05e-1)" "unprognostic (3.64e-7)" "prognostic unfavorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (6.51e-4)" "unprognostic (2.82e-3)" "unprognostic (0.00e+0)" "unprognostic (3.25e-2)" "unprognostic (8.13e-2)" "unprognostic (2.03e-1)" "unprognostic (1.04e-2)" 0.1 0.0 0.0 1.7 0.0 6.6 0.3 0.0 0.1 0.2 0.0 1.1 1.1 0.1 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 2.3 1.3 0.5 0.0 0.4 0.6 1.5 0.1 23.6 0.0 0.0 3.5 0.4 0.4 0.0 19.3 15.8 16.4 8.2 1.8 3.3 8.0 23.4 8.6 25.3 14.9 5.8 16.5 21.2 3.4 6.2 25.1 8.8 17.4 9.3 36.6 72.1 11.4 14.7 11.9 15.2 0.5 79.1 9.7 0.3 0.5 26.2 5.6 5.2 9.9 53.9 15.3 99.1 16.7 8.4 80.7 30.2 7.5 5.7 11.5 16.2 11.2 6.8 6.8 2.6 12.8 8.9 11.7 13.4 6.3 7.2 10.9 20.4 4.7 15.2 11.8 7.8 24.0 6.8 4.8 33.5 10.1 27.8 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.1 0.4 1.2 0.0 0.2 0.1 0.4 0.0 1.3 0.0 0.0 2.6 1.6 0.5 0.0 0.0 0.1 0.1 0.6 0.3 0.0 14.7 0.1 0.2 3.3 0.9 0.0 0.5 0.0 4.8 0.4 0.0 1.5 0.0 0.1 1.0 0.0 1.3 0.4 0.2 0.0 1.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 6.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.5 2.7 2.4 4.5 1.3 0.3 1.0 0.5 1.2 0.2 NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 17.9;lymphoid tissue: 19.2;testis: 67.1" "Group enriched" "Detected in many" 4 "Early spermatids: 76.1;Spermatocytes: 244.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "CAB017530, HPA064967" Enhanced Supported Nucleoplasm,Centrosome NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "CAB017530: AB_1126558, HPA064967: AB_2685393" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (1.83e-1)" "unprognostic (1.35e-2)" "prognostic unfavorable (9.47e-6)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.95e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-3)" "unprognostic (8.49e-2)" "unprognostic (0.00e+0)" "unprognostic (8.21e-2)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.71e-1)" 0.7 0.4 0.5 5.3 0.4 17.9 1.5 0.9 0.6 1.1 0.6 5.9 7.4 1.3 0.5 4.4 2.2 0.8 0.4 0.5 0.3 0.3 0.7 0.7 9.0 0.4 0.2 0.4 0.1 0.1 0.0 3.2 0.3 2.5 7.6 1.5 0.8 0.2 0.4 4.3 6.9 2.0 0.2 1.7 2.7 67.1 0.6 19.2 0.4 0.2 10.6 1.3 1.6 0.9 86.0 60.5 45.3 32.6 2.6 4.5 49.7 32.4 30.1 55.4 47.5 32.3 81.7 45.1 15.2 25.2 35.1 44.5 39.9 24.2 69.6 69.5 33.2 21.6 51.4 44.2 0.4 43.2 28.3 1.4 2.9 42.9 45.9 13.4 36.3 45.2 59.9 76.9 56.0 23.6 47.3 28.8 43.0 55.0 30.5 46.2 69.2 68.7 19.7 24.2 41.0 45.0 46.6 51.5 39.3 38.4 79.4 25.1 19.0 27.6 54.1 54.8 88.3 31.6 62.6 59.6 24.1 32.6 46.8 1.2 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.1 0.0 0.4 0.3 0.2 0.7 1.5 0.1 0.2 1.6 0.3 0.5 0.4 0.9 0.6 0.5 0.3 0.4 0.2 0.3 0.2 0.6 0.9 0.1 0.0 0.5 0.3 1.7 2.9 0.7 3.8 0.6 11.3 1.9 2.2 0.5 0.0 2.9 0.0 0.0 9.4 0.8 1.9 0.0 0.2 76.1 15.2 0.7 0.8 0.0 39.6 0.8 0.2 14.1 1.4 5.6 1.5 0.0 3.6 3.6 0.7 5.8 3.3 0.0 3.2 10.2 2.5 1.1 39.0 2.5 2.1 0.0 0.0 0.0 1.6 2.1 0.0 0.1 0.0 2.5 0.7 5.4 0.7 2.1 0.1 5.2 1.8 6.6 0.0 1.5 244.2 26.1 8.6 1.7 1.4 2.0 0.9 9.5 1.4 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" 66.8 46.3 36.8 22.5 39.3 33.4 56.8 40.0 56.0 35.6 37.4 51.4 31.3 35.9 51.9 27.9 35.3 29.0 110.4 37.5 40.9 64.2 39.5 31.8 30.0 40.2 39.7 38.0 39.9 43.3 45.1 38.1 41.4 34.3 38.1 56.9 41.2 36.5 140.8 22.3 33.4 33.1 39.9 31.0 43.8 34.6 39.0 22.8 41.9 120.2 29.5 44.8 31.1 42.0 59.3 59.2 56.1 55.5 70.4 75.4 61.6 61.0 62.0 59.0 47.8 114.7 56.9 42.4 30.0 57.0 85.6 25.4 63.7 64.2 79.5 77.8 62.3 43.5 38.2 102.0 70.1 73.7 59.2 58.4 37.2 67.5 41.2 56.0 65.6 41.8 80.1 41.8 99.1 11.9 39.1 119.0 53.9 62.9 64.3 42.6 85.5 15.6 83.5 57.6 45.9 34.3 35.2 32.2 92.5 57.6 40.8 49.4 67.8 71.3 47.1 52.2 80.8 53.8 48.4 23.1 54.2 74.7 55.8 20.2 13.6 25.5 15.9 18.6 15.6 21.7 16.3 18.9 12.4 25.1 16.9 18.6 4.3 18.0 28.5 25.0 24.8 12.3 36.8 39.3 40.0 56.0 37.5 40.9 40.2 39.7 41.4 39.9 39.0 42.0 30.6 32.1 22.5 9.8 37.0 16.2 35.9 96.7 21.1 23.9 33.2 29.6 92.3 37.1 42.6 38.6 12.5 113.9 34.1 34.6 189.8 56.9 111.0 40.0 27.1 34.9 53.3 25.7 15.4 60.9 70.5 30.9 20.4 25.3 58.3 21.6 33.5 32.0 82.6 18.5 18.8 47.7 57.0 35.8 24.0 34.2 34.8 30.2 39.2 10.3 66.8 55.6 46.4 21.1 27.1 50.3 39.7 36.9 25.4 28.8 56.3 163.0 58.9 33.4 46.0 36.9 44.1 82.9 60.4 18.8 14.9 61.3 33.3 42.7 46.3 35.4 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NIPAL3 "DJ462O23.2, NPAL3" ENSG00000001461 "NIPA like domain containing 3" Q6P499 1 24415802-24472976 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 88.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Oligodendrocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 101.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039978 Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA039978: AB_10697712" "unprognostic (9.36e-2)" "unprognostic (7.63e-2)" "unprognostic (2.88e-2)" "unprognostic (1.19e-2)" "unprognostic (5.96e-2)" "unprognostic (5.38e-2)" "unprognostic (3.72e-3)" "unprognostic (3.60e-2)" "unprognostic (2.43e-1)" "unprognostic (6.66e-2)" "unprognostic (2.79e-1)" "unprognostic (3.14e-1)" "prognostic favorable (3.03e-7)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (3.95e-4)" "unprognostic (2.85e-1)" 8.4 7.4 49.6 8.4 67.3 8.4 12.9 67.7 58.5 9.6 25.8 13.8 11.3 6.2 11.7 15.9 14.6 8.9 12.8 43.6 58.1 13.8 3.5 13.9 11.6 61.8 58.6 7.2 17.1 21.9 7.3 3.5 65.0 55.9 14.4 27.7 15.2 7.6 5.9 14.0 12.7 12.3 56.1 7.8 14.8 4.9 65.0 13.2 29.2 11.9 13.1 8.0 10.4 88.5 32.4 12.1 1.1 4.2 18.9 20.7 4.5 101.8 71.7 35.0 26.2 4.5 36.4 15.4 30.2 55.2 7.3 31.5 12.5 37.1 37.3 29.5 38.1 16.0 18.5 5.4 17.7 14.2 14.4 20.7 36.1 22.3 75.7 34.8 12.2 27.5 9.5 9.7 22.4 7.2 11.5 6.6 8.3 15.4 34.0 5.5 0.1 17.1 41.6 10.1 44.6 4.3 13.1 19.5 26.9 8.6 26.0 10.6 17.9 31.5 6.7 10.9 22.9 29.4 24.1 5.4 21.4 26.8 28.8 16.9 5.8 7.9 16.7 5.7 16.9 22.1 28.8 22.5 11.2 20.1 38.9 24.8 2.5 15.6 4.2 14.6 31.8 16.0 49.6 67.3 67.7 58.5 43.6 58.1 61.8 58.6 65.0 56.1 65.0 88.5 17.1 48.1 27.5 8.8 15.4 9.2 13.5 25.7 14.8 50.3 15.9 12.2 25.9 15.7 24.7 40.5 110.5 3.8 32.1 25.0 3.9 13.1 3.6 11.0 3.5 10.2 18.7 26.1 29.3 15.5 4.7 7.4 16.8 18.3 13.3 10.5 9.3 3.8 4.5 13.5 32.2 16.7 16.2 7.0 7.8 8.0 4.1 5.5 14.2 10.3 8.6 18.7 23.7 24.6 91.8 22.6 22.6 5.3 16.0 34.5 33.2 4.5 16.5 53.6 0.0 4.4 5.9 2.6 6.0 20.0 16.3 4.2 25.3 8.2 17.2 20.9 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NIPSNAP2 GBAS ENSG00000146729 "Nipsnap homolog 2" O75323 7 55951793-56000181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 266.5;skeletal muscle: 645.5;tongue: 784.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 226.9;Endometrial ciliated cells: 107.5;Proximal tubular cells: 106.8" "Cancer enhanced" "Detected in all" "glioma: 73.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 301.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063084 Enhanced Supported Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA063084: AB_2684938" "unprognostic (6.88e-2)" "unprognostic (6.53e-3)" "unprognostic (8.20e-3)" "unprognostic (4.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.53e-3)" "unprognostic (5.95e-3)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (6.38e-3)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "prognostic favorable (3.02e-8)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (6.65e-3)" "unprognostic (3.59e-1)" 61.2 70.3 46.0 25.4 48.4 39.2 59.0 47.2 56.9 45.4 50.8 56.0 31.4 41.1 36.6 49.0 50.4 27.5 266.5 45.1 49.5 63.8 14.5 36.9 26.4 45.2 48.7 34.7 49.2 70.4 27.1 31.0 47.1 53.4 53.8 27.6 79.2 55.9 645.5 21.9 32.4 46.6 49.0 26.1 46.5 20.5 50.0 40.1 86.5 784.2 28.7 40.8 26.0 47.6 301.3 52.3 67.5 112.6 38.7 65.8 33.1 24.7 58.2 69.7 53.5 36.5 64.9 43.8 40.5 46.6 67.5 39.1 51.4 52.2 68.7 27.9 75.4 31.1 27.6 46.9 54.6 68.0 30.2 60.3 78.4 23.8 64.5 79.1 74.6 62.2 56.2 41.9 54.8 13.4 68.1 70.4 66.7 66.5 52.3 68.0 31.3 90.8 94.6 46.7 71.7 80.8 56.2 67.0 78.3 53.0 129.9 72.3 43.9 31.7 47.4 11.3 52.0 34.1 30.9 81.2 35.1 41.9 95.7 48.2 86.6 39.1 22.6 86.4 27.2 37.7 28.8 23.8 91.7 37.0 34.2 25.2 15.3 41.9 69.1 38.1 37.9 72.4 46.0 48.4 47.2 56.9 45.1 49.5 45.2 48.7 47.1 49.0 50.0 47.6 45.4 51.3 57.7 0.0 10.3 0.0 0.0 0.0 0.0 0.0 80.4 63.8 0.0 0.0 43.3 62.5 0.0 76.0 20.1 0.0 226.9 74.8 0.0 107.5 56.1 22.1 0.0 0.0 0.0 57.2 56.4 23.4 0.0 57.6 16.4 64.7 0.0 0.0 88.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 39.8 0.0 0.0 0.0 0.0 46.2 0.0 0.0 5.2 0.0 0.0 106.8 88.2 0.0 0.0 0.0 26.7 0.0 0.0 0.0 0.0 51.4 12.3 74.0 0.0 0.0 NME5 "nm23-H5, RSPH23" ENSG00000112981 "NME/NM23 family member 5" P56597 5 138115175-138139443 "Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 37.2;testis: 53.3" "Group enriched" "Detected in many" 4 "Early spermatids: 704.9;Endometrial ciliated cells: 205.8;Late spermatids: 256.5;Respiratory ciliated cells: 431.9;Spermatocytes: 326.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 29.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035648, HPA044555, HPA058103" Enhanced Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nuclear bodies" "HPA035648: AB_2674719, HPA044555: AB_10960286, HPA058103: " "unprognostic (2.49e-2)" "unprognostic (7.63e-4)" "unprognostic (9.97e-2)" "prognostic favorable (7.24e-5)" "unprognostic (3.27e-2)" "unprognostic (2.27e-1)" "unprognostic (3.04e-3)" "unprognostic (3.06e-1)" "unprognostic (1.34e-1)" "unprognostic (2.39e-2)" "unprognostic (1.83e-2)" "unprognostic (2.14e-1)" "prognostic favorable (1.76e-4)" "unprognostic (9.14e-4)" "unprognostic (1.11e-3)" "unprognostic (3.45e-1)" "unprognostic (3.16e-2)" 1.4 6.5 9.7 0.5 10.5 0.0 4.5 9.2 11.7 8.6 18.6 2.1 0.2 4.9 23.1 1.0 37.2 8.7 3.6 10.5 9.2 20.5 0.5 4.5 0.4 10.5 12.3 5.3 4.4 24.3 8.9 0.1 12.1 5.0 1.1 12.9 3.7 4.5 0.4 0.3 0.6 3.1 9.6 0.2 2.8 53.3 11.0 0.7 12.4 0.6 0.2 2.1 0.6 8.9 0.0 0.0 3.9 4.3 0.0 0.0 0.0 0.7 0.4 0.7 0.3 0.1 1.8 0.0 1.1 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 1.7 0.0 0.0 2.1 0.0 0.9 0.0 3.8 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.4 0.0 0.0 0.0 29.9 0.0 6.7 2.5 0.0 0.8 4.9 1.7 0.5 1.6 0.0 0.7 0.0 0.0 0.9 0.4 0.8 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 10.5 9.2 11.7 10.5 9.2 10.5 12.3 12.1 9.6 11.0 8.9 1.0 6.4 7.5 26.8 0.3 0.6 8.5 41.1 0.0 11.7 9.0 7.9 4.3 8.6 38.1 33.1 14.6 0.5 0.1 0.3 86.1 23.8 704.9 205.8 9.2 3.5 5.4 0.0 57.9 4.0 0.0 4.2 2.6 12.7 0.0 7.7 3.6 0.6 0.1 6.7 42.2 3.3 44.7 0.0 0.3 256.5 9.0 1.4 10.6 3.7 0.6 19.1 0.0 11.1 8.1 4.2 0.3 13.9 0.0 4.8 0.2 92.3 431.9 25.8 0.0 0.5 12.6 326.8 24.7 0.0 0.3 0.0 0.8 10.9 1.7 5.9 NME7 "CFAP67, FLJ37194, NM23-H7" ENSG00000143156 "NME/NM23 family member 7" Q9Y5B8 1 169132531-169367948 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 274.9;Inhibitory neurons: 307.2;Oligodendrocytes: 277.7;Respiratory ciliated cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028334, HPA038014, HPA054289" Approved Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA028334: , HPA038014: AB_10673037, HPA054289: AB_2682437" "unprognostic (1.28e-1)" "unprognostic (8.52e-2)" "unprognostic (6.21e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" "unprognostic (7.44e-3)" "prognostic unfavorable (3.24e-5)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (6.63e-2)" "unprognostic (2.67e-2)" "unprognostic (1.12e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" 6.7 10.6 9.4 5.5 9.9 3.5 11.1 8.4 12.2 13.0 11.8 9.8 3.9 12.9 13.3 7.5 27.7 10.0 6.2 10.8 10.8 12.5 7.9 7.6 5.6 10.2 10.0 13.6 7.2 18.3 14.2 4.8 9.9 8.0 5.6 20.7 4.3 11.5 4.1 4.0 4.6 14.9 9.3 4.4 5.8 16.0 9.9 11.1 13.6 4.9 6.4 8.8 6.2 9.6 24.3 23.6 26.4 20.9 25.1 26.1 9.4 16.6 24.2 28.5 35.8 13.8 33.7 7.1 29.4 14.5 38.8 16.2 15.6 35.3 46.1 25.5 12.3 12.5 21.3 14.1 18.5 23.8 8.3 18.8 20.1 29.5 38.3 39.2 40.8 21.1 12.6 9.5 28.8 7.1 22.7 16.8 26.5 27.4 25.2 16.1 29.4 15.3 46.0 7.3 27.5 40.6 23.0 7.6 18.4 28.3 24.4 16.4 25.4 17.4 59.5 16.5 40.2 11.7 21.3 14.8 19.8 8.2 17.8 1.6 3.9 2.1 9.6 6.3 11.6 9.9 12.0 9.9 6.3 9.3 10.1 11.7 1.1 11.4 9.8 5.1 14.9 5.3 9.4 9.9 8.4 12.2 10.8 10.8 10.2 10.0 9.9 9.3 9.9 9.6 12.3 6.4 10.9 97.6 9.0 14.4 34.5 61.9 15.4 18.9 13.7 14.7 5.1 20.0 29.3 27.6 25.0 7.6 9.2 2.1 23.5 26.6 43.2 75.7 20.4 12.8 17.5 13.7 274.9 8.9 7.4 21.1 12.8 22.2 21.5 21.8 13.9 11.2 14.6 28.6 307.2 4.1 36.7 4.1 11.9 13.8 18.0 6.5 8.8 64.6 3.3 23.8 10.3 106.1 277.7 16.9 6.0 20.7 7.2 8.6 4.9 40.9 142.9 64.9 19.7 21.2 24.7 67.7 21.9 9.2 10.2 2.7 18.7 26.4 6.0 16.5 NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: AB_10601274" "unprognostic (8.76e-2)" "unprognostic (8.94e-2)" "unprognostic (8.38e-2)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "unprognostic (5.77e-2)" "unprognostic (2.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.64e-5)" "unprognostic (1.26e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-3)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "unprognostic (4.79e-2)" 44.3 43.9 29.5 21.7 30.8 29.5 42.0 32.2 34.0 37.5 28.2 44.8 26.8 37.7 23.4 38.2 35.5 16.6 48.2 28.7 31.1 58.5 37.9 32.2 25.8 30.9 31.4 40.7 48.9 40.2 35.9 21.1 31.0 35.1 19.8 16.6 38.0 19.2 44.5 36.9 36.4 16.0 30.8 37.8 37.9 41.7 30.7 15.2 37.1 17.1 20.3 41.4 34.9 33.8 71.7 37.2 31.7 42.7 26.9 26.1 74.4 71.8 29.3 48.4 44.4 60.0 24.9 97.8 137.4 34.4 57.7 46.5 46.9 42.4 47.8 57.5 105.0 91.2 36.3 104.0 45.4 112.0 61.4 25.5 41.5 42.5 24.2 29.8 33.6 45.5 135.7 22.2 44.7 38.1 70.6 147.6 42.1 37.0 74.1 74.4 46.8 140.5 57.9 21.7 92.5 60.3 40.9 88.0 94.9 36.2 53.6 42.8 65.7 48.0 51.9 57.8 108.3 66.2 123.2 100.2 30.7 70.7 75.6 34.5 59.6 82.1 59.2 76.4 68.2 104.0 84.7 71.4 73.2 87.8 90.7 69.0 27.4 61.9 82.9 91.4 96.0 67.9 29.5 30.8 32.2 34.0 28.7 31.1 30.9 31.4 31.0 30.8 30.7 33.8 103.1 93.0 73.5 10.4 112.5 90.8 117.3 151.0 50.1 62.1 78.9 97.0 214.9 68.6 112.0 57.0 22.9 137.4 71.5 72.7 123.3 188.7 202.3 105.8 95.0 109.2 37.1 89.4 14.0 261.2 153.8 90.9 58.1 91.6 90.6 67.0 61.1 61.8 115.1 48.8 17.1 97.8 130.2 52.6 81.8 38.9 82.6 78.5 101.4 8.4 119.7 124.2 78.2 13.6 19.0 175.0 94.3 79.4 138.8 121.7 81.2 163.6 135.6 61.7 65.7 92.5 119.4 186.3 112.9 70.8 90.5 155.3 99.5 99.2 91.0 117.2 NOMO1 PM5 ENSG00000103512 "NODAL modulator 1" Q15155 16 14833721-14896157 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 133.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 76.3;Hep G2: 126.5;LHCN-M2: 65.8;RPMI-8226: 90.4;SiHa: 144.9" "CAB025192, HPA046697, HPA061174" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Endoplasmic reticulum" "CAB025192: , HPA046697: AB_2679758, HPA061174: AB_2684444" "unprognostic (5.33e-3)" "unprognostic (1.60e-1)" "unprognostic (5.27e-1)" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.51e-1)" "unprognostic (4.18e-3)" "unprognostic (2.08e-2)" "unprognostic (2.28e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-2)" "unprognostic (8.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.09e-1)" "unprognostic (1.50e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (3.15e-4)" 24.1 27.6 4.4 10.3 4.4 0.0 23.6 4.4 16.0 22.0 4.4 32.3 0.7 25.6 0.0 24.9 20.4 0.4 92.3 4.5 9.6 32.0 28.3 26.9 2.7 4.8 4.3 21.3 133.9 0.0 29.2 6.8 4.5 21.6 8.2 4.2 31.1 4.5 101.7 28.1 26.1 8.2 4.3 19.9 36.4 31.0 4.5 0.0 21.5 1.4 0.2 28.8 22.2 5.1 1.2 56.8 51.4 76.3 0.0 4.6 42.2 3.4 9.1 11.5 11.0 0.8 2.8 4.3 2.8 8.8 1.0 0.7 8.8 0.7 11.3 6.2 0.0 3.7 57.8 126.5 48.7 5.8 2.7 0.6 0.5 6.2 6.3 1.2 9.0 0.0 29.7 2.6 65.8 0.0 1.6 0.0 0.0 0.0 0.0 1.9 4.3 90.4 0.0 2.6 1.1 45.8 144.9 0.0 0.1 1.7 63.1 0.6 2.1 1.9 0.1 2.6 58.1 0.3 2.1 4.7 2.3 2.3 1.3 3.7 0.2 0.2 0.0 0.4 0.3 0.0 0.1 0.3 0.1 0.5 0.2 0.3 0.6 1.9 2.0 1.6 0.3 0.6 4.4 4.4 4.4 16.0 4.5 9.6 4.8 4.3 4.5 4.3 4.5 5.1 5.6 3.2 10.5 9.1 5.3 6.4 1.4 10.6 3.4 8.7 7.8 5.8 58.4 7.2 8.6 11.0 6.2 6.8 4.2 14.4 0.0 15.6 32.9 3.3 3.1 7.3 7.7 5.5 12.7 29.4 12.4 7.9 11.7 4.2 23.6 13.0 7.9 7.6 6.3 35.3 16.2 11.7 2.0 12.7 2.8 12.0 2.8 10.3 5.4 7.5 11.2 5.4 16.5 13.6 32.1 27.4 10.8 6.4 16.2 2.1 16.1 7.9 7.4 8.5 6.6 5.7 7.5 16.1 13.1 6.7 5.8 9.6 4.2 9.5 13.0 1.6 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NRL "D14S46E, NRL-MAF, RP27" ENSG00000129535 "Neural retina leucine zipper" P54845 14 24078662-24115010 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 75 "retina: 317.3" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 3720.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SuSa: 4.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "CAB026066, HPA064599" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 79: Retina - Phototransduction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "CAB026066: , HPA064599: AB_2685295" "unprognostic (2.71e-2)" "unprognostic (8.17e-4)" "unprognostic (4.60e-2)" "unprognostic (1.80e-1)" "unprognostic (7.23e-2)" "unprognostic (1.99e-2)" "unprognostic (5.29e-2)" "unprognostic (1.88e-5)" "unprognostic (3.59e-2)" "unprognostic (7.84e-3)" "unprognostic (1.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.38e-5)" "unprognostic (2.56e-2)" "unprognostic (1.10e-1)" "unprognostic (1.73e-1)" "unprognostic (1.35e-3)" 0.8 2.5 1.7 0.5 1.5 0.5 1.0 2.3 2.2 1.1 0.6 0.9 1.1 1.1 0.7 1.1 1.0 0.9 2.2 1.5 1.5 3.1 3.6 1.0 1.0 2.3 1.8 1.2 1.7 1.9 2.4 0.3 1.7 1.5 0.3 317.3 1.0 0.7 2.5 0.7 1.3 0.3 1.7 2.1 1.2 4.2 1.6 1.2 2.7 1.4 0.7 1.1 0.8 1.7 0.3 1.2 1.6 1.6 0.3 0.2 0.4 0.3 0.3 0.5 0.3 0.7 0.5 1.2 0.4 0.5 1.0 0.5 0.6 0.3 0.2 0.6 0.5 0.7 0.6 2.2 0.6 1.4 1.6 0.4 0.5 0.2 0.7 0.7 0.5 2.2 0.7 1.2 0.3 0.9 1.2 0.6 1.8 1.8 0.9 1.2 1.5 0.0 0.4 1.3 1.7 1.2 0.8 0.7 0.8 4.8 0.9 1.5 0.4 1.1 0.5 0.1 0.7 3.6 1.9 1.5 0.3 0.9 1.1 0.2 0.3 1.3 0.2 0.4 0.1 1.0 0.2 0.4 0.3 0.7 0.8 0.6 0.1 0.5 0.3 0.4 0.2 0.3 1.7 1.5 2.3 2.2 1.5 1.5 2.3 1.8 1.7 1.7 1.6 1.7 1.4 0.0 0.5 5.5 6.2 0.8 1.6 0.1 1.2 434.4 2.0 1.9 2.1 0.0 0.7 7.3 431.6 1.4 3.2 1.5 13.7 0.6 2.7 1.3 0.7 24.1 1.8 3.2 1.8 1.1 0.9 0.7 2.6 1.0 0.0 0.7 0.7 3.3 2.0 250.7 2.6 1.7 0.0 1.3 0.4 4.2 1.2 1.4 1.8 0.0 1.1 636.4 5.2 2.0 4.4 0.3 5.3 1.9 1.7 2.0 5.6 6.7 0.1 3720.7 0.0 1.2 0.7 9.7 4.3 2.2 0.4 2.5 2.6 2.3 1.0 2.1 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NT5DC1 "dJ486I3.1, MGC24302, NT5C2L1" ENSG00000178425 "5'-nucleotidase domain containing 1" Q5TFE4 6 116100851-116249497 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 117.6" "Cell type enriched" "Detected in all" 4 "Oligodendrocytes: 429.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030352, HPA079264" Uncertain Approved Nucleoplasm,Cytosol NA NA 140000 "Cluster 37: B-cells - Transcription" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA030352: AB_2154066, HPA079264: " "unprognostic (1.30e-1)" "unprognostic (2.92e-1)" "prognostic favorable (2.61e-4)" "unprognostic (1.14e-1)" "unprognostic (3.13e-2)" "unprognostic (7.80e-2)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (2.31e-2)" "unprognostic (4.61e-1)" "unprognostic (1.47e-1)" "prognostic favorable (7.49e-7)" "unprognostic (1.41e-1)" "unprognostic (8.53e-2)" "unprognostic (2.79e-1)" "unprognostic (9.63e-2)" 19.5 24.0 11.4 12.7 24.6 10.0 19.2 22.7 15.0 10.4 117.6 19.8 29.5 9.1 22.4 16.5 20.6 15.7 25.9 11.0 16.3 28.2 42.6 16.7 21.4 24.1 20.9 13.2 22.2 23.8 9.6 8.3 24.1 28.3 19.9 11.2 22.7 16.6 21.5 10.7 26.8 11.3 21.0 13.5 21.6 10.6 19.3 14.5 28.3 23.2 22.4 15.8 9.4 40.9 24.7 20.3 17.7 23.7 19.2 11.6 31.0 17.7 40.3 27.4 32.2 29.4 24.8 50.3 37.4 15.9 29.7 38.7 12.1 28.1 23.8 78.4 26.7 21.0 16.7 31.0 20.9 46.8 1.9 21.7 22.2 17.6 15.0 59.2 24.7 30.0 26.6 27.5 34.8 25.3 9.0 16.3 16.2 54.1 27.0 52.3 48.3 27.2 25.5 29.2 11.8 17.6 37.9 28.7 26.5 19.4 26.6 9.3 21.6 12.3 20.8 23.7 35.6 40.2 59.2 39.8 29.3 31.0 22.4 14.5 18.2 33.2 20.2 10.5 31.4 41.3 29.8 25.4 24.6 30.1 28.2 24.3 12.9 23.1 12.7 12.4 32.4 19.7 11.4 24.6 22.7 15.0 11.0 16.3 24.1 20.9 24.1 21.0 19.3 40.9 15.4 64.1 45.7 62.3 37.9 26.1 37.9 66.5 29.6 14.0 30.3 23.6 44.2 25.8 44.5 18.4 27.1 41.6 24.9 19.1 64.6 39.6 19.8 32.9 10.7 21.7 26.5 16.2 96.1 40.8 30.4 14.0 26.5 19.0 23.5 16.2 33.5 49.3 31.8 45.4 70.1 30.6 30.5 29.2 14.2 8.3 19.0 18.5 19.6 54.4 49.6 19.8 10.3 29.7 429.4 28.8 19.6 20.7 25.3 28.0 54.6 57.4 76.7 20.2 32.9 29.2 23.9 17.2 28.5 27.4 21.5 25.6 23.8 18.3 35.9 31.5 NTRK3 TRKC ENSG00000140538 "Neurotrophic receptor tyrosine kinase 3" Q16288 15 87859751-88256768 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8" "Cell type enhanced" "Detected in many" "Astrocytes: 239.3;Early spermatids: 119.6;Excitatory neurons: 360.0;Inhibitory neurons: 277.8;Late spermatids: 148.9;Microglial cells: 177.1;Oligodendrocyte precursor cells: 499.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "U-138 MG: 100.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009233, HPA027484, HPA048065" Approved Supported "Nuclear membrane,Nucleoli,Nucleoli rim" NA NA 19000000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim" "Nuclear membrane" "CAB009233: AB_632555, HPA027484: AB_2672297, HPA048065: AB_2680245" "unprognostic (1.27e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-2)" "unprognostic (2.04e-2)" "unprognostic (1.65e-1)" "unprognostic (3.34e-1)" "unprognostic (3.18e-2)" "unprognostic (2.23e-2)" "unprognostic (2.34e-1)" "unprognostic (3.91e-1)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-3)" "unprognostic (6.45e-3)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (2.49e-3)" 12.8 3.7 31.3 0.8 33.2 0.1 7.8 30.7 34.3 12.8 0.0 3.4 0.5 10.4 3.2 1.3 15.0 1.6 5.8 38.8 25.8 5.1 1.0 5.3 1.2 21.5 19.6 7.2 1.0 0.1 12.2 1.0 22.1 9.0 2.0 5.2 6.8 4.3 1.8 4.8 2.2 3.7 10.9 2.5 3.2 9.8 33.4 1.2 3.0 1.9 2.0 8.7 7.4 21.5 0.0 13.1 2.7 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 2.5 0.0 0.0 0.0 2.6 0.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.9 0.1 0.1 0.0 100.6 1.8 0.0 1.3 0.0 0.0 0.0 3.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 31.3 33.2 30.7 34.3 38.8 25.8 21.5 19.6 22.1 10.9 33.4 21.5 0.5 0.0 0.0 239.3 0.0 0.5 6.4 0.0 0.0 53.8 3.7 6.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 119.6 0.4 25.0 1.2 0.0 0.0 360.0 0.0 0.0 5.7 0.0 0.5 0.0 0.0 2.2 0.0 1.0 1.7 277.8 0.0 0.0 0.0 0.6 148.9 3.4 0.6 0.0 177.1 0.0 8.6 0.0 499.6 7.4 0.0 0.0 27.4 0.0 1.3 0.0 0.1 0.0 3.7 52.6 20.3 40.9 11.0 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.7 NUBP1 "CIAO5, NBP1, NBP35" ENSG00000103274 "Nucleotide binding protein 1" P53384 16 10743786-10769351 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041656, HPA041799" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA041656: AB_10960278, HPA041799: AB_10960692" "unprognostic (2.51e-2)" "prognostic favorable (2.81e-5)" "unprognostic (4.01e-3)" "unprognostic (1.66e-3)" "unprognostic (2.81e-1)" "unprognostic (7.04e-2)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (8.28e-2)" "unprognostic (5.08e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "prognostic favorable (7.61e-8)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (8.23e-2)" "unprognostic (1.69e-2)" 22.7 39.3 12.6 25.9 12.7 31.0 22.0 13.6 16.5 19.9 15.2 27.4 21.6 21.3 24.8 19.7 25.6 19.6 46.7 12.5 13.1 27.8 31.1 21.2 31.1 13.2 12.7 22.9 31.9 30.3 17.0 19.6 13.1 21.1 20.0 12.0 21.7 21.0 37.7 15.7 22.1 22.7 13.5 28.5 28.7 17.3 12.9 21.4 23.5 34.7 36.9 24.4 16.8 13.8 31.3 55.9 37.2 23.1 16.8 31.0 35.5 29.9 27.9 51.4 42.6 49.0 33.2 53.7 60.5 36.7 40.0 33.5 34.9 30.7 38.2 84.8 43.9 30.3 39.3 80.4 33.7 27.7 34.3 29.2 23.0 35.2 19.2 28.6 34.2 20.6 43.3 31.7 38.3 72.0 18.2 40.2 46.1 25.5 29.9 72.5 48.2 58.6 37.0 37.7 22.9 33.5 51.8 38.6 29.2 23.7 39.3 30.2 30.5 40.0 40.8 49.9 38.2 56.0 52.0 42.4 36.7 55.3 48.0 3.8 82.7 41.3 39.2 88.2 35.9 75.6 34.7 39.1 89.7 69.3 29.9 31.1 9.7 35.2 66.7 44.0 46.5 52.9 12.6 12.7 13.6 16.5 12.5 13.1 13.2 12.7 13.1 13.5 12.9 13.8 20.3 6.4 23.1 3.9 33.7 14.3 26.6 39.8 10.8 17.0 14.9 17.3 6.0 34.3 32.2 23.9 6.2 49.6 19.0 12.3 66.5 54.2 2.4 17.3 12.2 21.3 16.8 12.0 8.4 79.1 29.2 16.7 15.8 17.2 24.1 17.3 14.6 29.6 56.4 6.7 8.1 19.2 40.7 38.4 91.2 3.6 25.7 38.0 16.0 3.7 72.7 30.1 20.6 3.0 5.2 48.7 18.4 19.5 17.6 17.9 27.2 65.0 31.6 18.5 6.6 20.0 15.9 33.1 29.4 12.3 11.9 60.7 17.8 25.3 18.0 29.2 NUCB2 NEFA ENSG00000070081 "Nucleobindin 2" P80303 11 17208153-17349980 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "DNA-binding, Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 758.3;salivary gland: 771.4" "Cell type enhanced" "Detected in all" "Early spermatids: 690.6;Late spermatids: 508.5;Respiratory ciliated cells: 618.8;Syncytiotrophoblasts: 1158.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 1867.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008395, CAB015931, CAB079781" Enhanced Supported Enhanced "Golgi apparatus" "Secreted to blood" NA NA 1250000 690000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus" "CAB015931: , CAB079781: AB_2313672, HPA008395: AB_1854683" "unprognostic (2.49e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.27e-6)" "unprognostic (5.24e-3)" "unprognostic (2.51e-1)" "unprognostic (3.96e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "prognostic favorable (1.98e-4)" "unprognostic (1.46e-2)" "unprognostic (3.38e-2)" "prognostic unfavorable (3.94e-5)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (4.78e-2)" "unprognostic (8.02e-3)" 56.2 75.7 23.9 62.1 27.8 619.9 141.1 28.8 32.1 137.2 58.0 68.3 57.3 60.8 458.2 146.3 107.2 60.8 95.7 22.8 34.7 43.2 102.2 49.8 60.2 25.7 28.2 56.0 758.3 479.1 113.0 90.9 26.8 70.9 68.4 64.5 771.4 190.9 38.5 21.1 40.7 78.5 26.2 42.2 92.9 119.2 28.4 334.2 153.9 30.4 78.5 61.8 44.9 26.6 119.9 49.0 53.7 163.4 118.9 162.3 65.0 260.5 381.0 115.1 203.0 48.7 26.8 182.9 63.5 250.7 107.1 50.1 34.4 66.8 178.7 126.7 76.3 135.8 57.8 85.2 340.5 1867.0 238.6 71.1 86.8 82.9 200.9 284.9 143.3 672.1 120.1 361.1 114.9 105.9 656.2 670.3 12.9 194.0 50.5 239.8 130.4 15.1 51.9 37.5 63.5 35.4 114.6 114.2 61.4 78.0 93.5 498.1 128.1 120.9 110.9 369.1 112.1 70.3 41.3 101.1 140.5 646.1 106.4 210.5 43.5 168.2 94.1 30.5 122.9 22.7 88.5 173.7 40.6 14.5 246.7 271.2 39.3 277.9 25.6 426.0 42.7 119.8 23.9 27.8 28.8 32.1 22.8 34.7 25.7 28.2 26.8 26.2 28.4 26.6 118.7 44.8 70.4 16.3 54.8 27.5 60.2 156.3 14.8 71.0 152.8 87.0 193.8 55.8 176.5 42.3 54.2 127.1 136.5 17.6 27.4 91.1 690.6 112.4 92.9 94.7 42.4 137.8 21.9 132.6 319.1 148.8 40.2 97.0 67.6 80.0 108.5 141.8 70.7 35.3 23.5 189.0 189.2 29.4 40.0 508.5 149.8 37.6 69.4 18.7 24.1 111.2 95.8 13.6 10.8 75.2 13.2 114.3 256.5 108.7 3.9 28.5 618.8 99.3 46.0 50.8 75.4 174.9 61.3 87.7 30.1 1158.2 92.3 88.3 45.3 61.2 NUCKS1 NUCKS ENSG00000069275 "Nuclear casein kinase and cyclin dependent kinase substrate 1" Q9H1E3 1 205712822-205750182 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062351, HPA063843" Supported Supported Nucleoplasm,Nucleoli No No 13000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Nucleoli "HPA062351: AB_2684745, HPA063843: AB_2685134" "unprognostic (1.68e-1)" "unprognostic (3.92e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.87e-1)" "unprognostic (2.93e-1)" "unprognostic (9.20e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (5.16e-3)" "unprognostic (1.18e-3)" "unprognostic (1.37e-1)" "unprognostic (5.82e-3)" "unprognostic (7.45e-3)" "unprognostic (1.44e-1)" "unprognostic (2.25e-2)" "unprognostic (7.57e-2)" 63.3 57.2 88.6 43.3 98.3 33.4 72.8 86.2 102.7 70.8 53.7 52.5 29.5 83.4 62.0 54.4 71.8 46.7 98.3 80.7 88.8 70.4 104.2 48.7 61.2 93.8 87.8 108.9 41.2 96.1 39.0 49.6 94.1 71.7 48.1 81.4 46.8 71.1 113.7 51.4 33.2 69.8 94.6 56.5 43.0 25.8 87.9 97.4 98.1 101.6 60.7 47.8 45.2 115.8 223.5 134.6 354.2 140.8 96.0 131.7 166.1 157.3 161.3 215.6 172.6 74.4 250.0 246.1 89.0 154.2 68.2 160.0 272.6 131.9 245.7 118.6 135.8 160.3 113.2 81.8 70.6 255.0 54.9 105.1 116.9 128.6 221.7 115.6 171.4 156.3 261.9 76.7 170.7 258.1 233.2 128.0 363.0 88.9 99.4 239.1 436.4 141.1 121.4 135.4 146.9 270.9 232.2 183.3 127.5 272.4 280.3 189.9 172.8 164.5 144.8 190.0 282.8 69.9 88.0 192.6 112.8 140.5 226.2 5.6 3.2 3.9 9.1 4.9 8.8 5.6 8.3 8.0 4.6 6.9 10.1 10.7 0.6 10.7 4.2 7.3 5.5 3.8 88.6 98.3 86.2 102.7 80.7 88.8 93.8 87.8 94.1 94.6 87.9 115.8 258.4 214.7 283.4 73.4 179.5 258.1 277.4 212.9 282.9 356.2 221.2 229.7 412.4 318.8 241.8 303.5 73.0 301.5 174.5 125.5 385.4 202.5 61.3 227.0 410.3 254.5 179.0 324.2 85.9 171.5 381.3 356.5 131.0 299.5 215.4 329.0 258.5 668.2 264.1 316.3 88.7 219.2 116.0 216.8 266.4 52.6 512.0 164.0 174.3 71.2 162.1 546.9 195.7 56.8 126.2 117.2 113.2 485.2 128.2 295.3 49.4 384.5 187.8 200.2 315.5 458.0 358.1 70.0 104.1 321.4 243.9 177.2 190.5 443.9 265.1 220.8 NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA038968: AB_10697402, HPA038969: AB_2676295" "unprognostic (9.48e-2)" "unprognostic (5.91e-3)" "unprognostic (2.64e-2)" "unprognostic (9.00e-3)" "unprognostic (4.99e-2)" "unprognostic (2.50e-3)" "unprognostic (2.29e-2)" "unprognostic (7.47e-3)" "prognostic unfavorable (1.25e-5)" "unprognostic (1.04e-1)" "unprognostic (8.50e-2)" "unprognostic (3.69e-1)" "unprognostic (4.63e-2)" "unprognostic (1.84e-3)" "unprognostic (3.35e-1)" "unprognostic (9.58e-2)" "unprognostic (8.93e-3)" 12.2 13.0 7.1 10.1 7.2 18.0 16.4 8.6 8.3 12.9 6.9 20.2 20.8 9.7 13.8 16.3 11.6 9.0 11.0 6.9 8.5 17.2 14.1 9.2 7.5 7.2 7.7 8.6 9.4 8.2 9.4 12.6 7.8 15.1 22.1 10.3 12.1 10.0 11.9 8.7 16.3 10.5 6.8 5.5 13.0 10.7 7.6 10.7 13.4 18.7 10.3 12.9 10.3 7.8 47.5 28.4 52.4 23.1 21.2 30.3 37.8 37.7 35.8 41.3 39.7 42.1 45.2 34.6 20.7 30.3 36.7 54.3 51.3 56.1 63.4 18.3 41.8 34.1 28.0 46.2 19.8 52.0 31.2 20.9 35.3 33.3 46.7 18.4 45.3 34.5 30.7 13.5 67.2 23.2 40.5 48.4 83.0 72.8 32.2 27.6 33.8 22.7 46.2 35.8 31.4 33.1 25.6 43.8 30.3 44.7 22.5 38.7 23.0 28.5 34.7 36.2 53.3 6.9 12.5 43.6 14.8 40.1 47.4 1.6 4.8 3.5 2.9 6.9 2.9 3.1 4.6 3.6 4.9 2.6 5.3 5.8 1.0 2.8 4.8 3.7 3.4 2.7 7.1 7.2 8.6 8.3 6.9 8.5 7.2 7.7 7.8 6.8 7.6 7.8 12.0 12.8 15.7 0.7 14.7 16.6 34.6 18.1 19.9 9.2 14.0 11.6 12.5 12.8 20.7 7.3 2.1 36.2 12.6 30.4 49.0 17.3 16.7 45.7 20.4 15.1 8.4 10.5 3.9 17.6 79.4 12.8 18.3 39.5 9.5 8.7 7.5 17.4 16.8 38.7 3.1 23.5 26.4 7.8 10.5 9.3 16.8 11.4 10.6 1.9 10.3 10.8 6.2 0.5 3.0 16.4 18.3 12.4 16.8 41.9 18.9 40.8 13.6 9.0 0.0 9.5 17.1 8.9 34.4 34.9 20.5 38.0 13.2 15.3 31.9 42.0 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 160.7" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" NA NA 9900 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 23.6 36.1 20.8 16.2 21.4 6.7 19.7 25.5 38.5 27.6 39.1 27.0 42.6 24.8 32.2 19.6 24.9 16.2 28.8 21.9 24.7 40.4 46.6 23.0 13.7 21.0 20.5 26.7 67.6 55.3 29.1 19.9 21.9 30.4 27.1 20.1 28.1 23.8 42.1 16.6 40.3 23.8 19.6 14.7 22.3 22.5 22.1 13.4 28.8 45.0 14.8 22.4 24.3 26.0 30.8 25.6 34.0 19.8 67.6 39.6 26.0 59.8 35.6 21.3 21.1 17.1 53.1 47.6 58.9 47.6 41.0 21.1 32.1 38.1 33.2 34.5 24.0 13.4 34.5 31.8 42.4 25.6 21.2 41.5 52.4 25.6 22.6 45.5 41.6 13.7 40.3 30.0 38.7 33.4 39.1 23.2 29.1 68.5 12.0 45.0 31.8 27.0 160.7 24.2 41.3 28.7 37.6 63.0 30.8 44.5 36.8 38.2 43.7 34.7 34.3 25.8 27.8 21.5 18.7 37.9 51.3 21.9 48.2 1.6 17.9 5.9 19.1 21.2 18.2 22.2 18.5 19.5 21.4 18.8 22.5 26.0 1.8 15.6 24.0 20.6 19.0 16.0 20.8 21.4 25.5 38.5 21.9 24.7 21.0 20.5 21.9 19.6 22.1 26.0 32.6 67.3 44.8 20.2 14.9 9.9 40.4 45.0 9.6 15.3 11.3 13.1 40.9 30.0 55.0 23.9 27.1 33.2 13.1 21.0 41.1 44.7 28.6 26.0 26.2 25.8 16.8 6.7 21.7 36.5 32.5 29.4 8.6 27.0 20.8 23.3 18.2 47.5 33.2 6.7 24.0 18.0 40.7 12.7 11.0 11.5 25.4 14.7 10.6 20.6 16.4 26.8 8.2 18.6 24.8 29.4 37.0 26.7 15.8 32.9 55.7 56.2 41.0 18.6 26.3 36.9 23.7 44.5 23.6 15.7 9.5 37.6 12.1 29.8 24.9 27.3 NUP62CL FLJ20130 ENSG00000198088 "Nucleoporin 62 C-terminal like" Q9H1M0 X 107123427-107206433 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.3;fallopian tube: 17.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 21.5;Endometrial ciliated cells: 26.6;Respiratory ciliated cells: 21.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 21.9;CAPAN-2: 23.5;HeLa: 30.7;K-562: 23.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001884 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA001884: AB_1079512" "unprognostic (1.62e-2)" "prognostic favorable (5.66e-5)" "unprognostic (8.80e-2)" "unprognostic (4.23e-2)" "unprognostic (1.44e-1)" "unprognostic (8.19e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (1.13e-1)" "unprognostic (2.58e-2)" "unprognostic (6.47e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-1)" "unprognostic (2.82e-3)" "unprognostic (4.52e-3)" 0.2 13.9 0.9 1.6 1.0 2.2 3.1 0.7 0.6 1.3 7.6 2.7 3.0 1.8 17.3 1.3 17.2 1.5 1.8 0.8 1.2 6.0 1.9 1.6 1.3 3.6 3.8 1.4 4.3 4.2 2.5 0.4 2.1 0.9 3.3 1.0 2.1 2.9 0.1 1.5 3.0 0.3 2.5 0.2 1.7 12.0 1.2 2.0 10.0 0.5 2.3 0.9 0.9 1.3 13.5 21.9 1.9 0.0 0.0 0.1 9.4 0.0 0.8 0.5 0.5 2.1 23.5 7.7 2.5 0.0 11.9 11.9 13.9 4.8 0.1 0.0 17.8 0.8 30.7 3.9 0.0 0.0 0.0 0.2 6.3 0.1 3.3 0.0 0.0 11.8 23.0 1.9 0.0 6.6 3.0 0.0 2.8 19.1 7.9 0.0 0.0 0.7 7.1 3.6 5.5 6.4 7.8 2.4 0.0 7.8 0.0 0.4 0.0 0.0 7.0 0.1 0.0 2.5 9.4 4.2 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.2 0.2 2.0 0.9 0.0 0.0 1.0 0.4 0.5 0.0 0.7 0.2 0.0 0.4 0.2 0.9 1.0 0.7 0.6 0.8 1.2 3.6 3.8 2.1 2.5 1.2 1.3 0.3 3.2 0.0 0.3 1.7 1.9 3.9 6.3 1.8 0.5 2.8 1.7 1.0 2.8 3.5 9.2 0.0 2.0 0.8 1.7 21.5 2.1 8.8 26.6 0.3 0.4 0.0 3.8 0.4 3.4 1.0 0.2 1.5 4.2 0.0 1.7 0.0 2.2 0.9 1.7 0.5 3.5 6.1 0.0 1.1 3.3 0.3 0.3 5.4 2.8 0.2 1.2 0.0 0.0 0.3 1.4 0.7 0.7 2.4 1.1 1.1 5.7 21.6 0.2 6.6 0.4 0.9 9.6 9.7 1.6 2.8 1.0 1.1 0.0 2.4 2.6 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 17.8 20.0 12.1 22.2 13.0 19.4 22.2 11.4 15.5 60.3 16.1 19.8 16.5 20.6 28.4 15.7 18.4 16.1 11.7 12.9 13.8 28.4 31.6 18.2 21.4 10.8 12.5 16.5 20.4 29.8 11.9 21.6 11.9 20.6 20.3 12.5 30.5 17.6 10.0 11.1 17.6 18.7 11.7 17.8 24.2 12.6 13.5 18.5 35.4 12.6 20.6 23.5 11.7 12.4 27.1 19.5 41.3 46.4 40.7 52.9 101.0 48.3 50.1 39.5 45.1 44.6 29.5 63.4 51.1 44.7 50.0 24.0 62.1 47.2 73.0 47.9 57.0 72.8 31.5 80.2 62.6 92.8 41.2 46.6 52.5 43.3 87.7 40.3 41.3 46.5 88.4 54.9 59.7 30.5 43.9 58.8 48.0 36.9 35.3 41.7 29.7 45.7 79.0 26.6 48.7 38.5 29.1 37.4 36.9 45.6 23.8 95.9 36.4 24.3 30.1 39.2 70.5 75.6 60.8 66.8 57.6 70.0 49.7 1.9 1.3 0.8 1.3 1.4 1.9 1.1 1.6 1.8 1.5 1.0 1.3 1.7 0.1 1.9 2.5 3.8 1.7 1.0 12.1 13.0 11.4 15.5 12.9 13.8 10.8 12.5 11.9 11.7 13.5 12.4 18.7 0.0 22.3 30.3 28.5 60.5 41.9 32.6 19.4 15.3 26.6 13.7 6.3 15.7 24.0 25.8 10.4 26.8 38.1 26.4 27.4 23.4 16.0 15.7 28.9 24.3 13.1 19.1 33.4 30.2 63.6 22.8 38.2 21.4 31.1 15.8 28.2 39.7 35.3 15.2 37.1 29.3 20.3 37.0 42.2 14.0 18.0 30.2 32.0 20.6 28.4 8.3 24.7 35.7 36.5 37.4 22.7 20.3 57.5 73.1 18.6 33.6 23.1 9.6 6.6 21.3 25.9 24.9 25.4 25.7 56.1 57.9 26.2 14.5 26.1 77.5 NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 88.6;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 266.7;Extravillous trophoblasts: 121.2;Granulosa cells: 93.3;Spermatocytes: 99.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 10.7;T-reg: 7.7" "Group enriched" "Detected in many" 15 "granulocytes: 10.7;T-cells: 7.7" "Low cell line specificity" "Detected in many" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: AB_2678220, HPA074847: AB_2732269" "unprognostic (1.19e-1)" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (8.78e-2)" "unprognostic (3.46e-2)" "unprognostic (2.97e-2)" "unprognostic (1.16e-3)" "unprognostic (1.74e-3)" "unprognostic (1.37e-2)" "unprognostic (4.14e-1)" "prognostic unfavorable (6.27e-4)" "unprognostic (8.49e-3)" "prognostic unfavorable (6.82e-14)" "unprognostic (4.76e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (1.22e-1)" 1.8 14.1 0.2 7.8 0.2 88.6 1.5 0.3 0.4 3.6 0.3 6.1 7.0 1.1 0.1 17.7 1.1 1.0 1.1 0.2 0.2 2.6 5.0 3.8 28.7 0.3 0.4 4.4 1.3 0.0 0.6 6.5 0.3 1.1 8.0 0.1 3.6 0.6 5.4 9.4 7.4 2.7 0.2 7.8 4.5 10.9 0.3 101.5 0.9 0.1 31.5 1.9 6.4 0.3 146.0 38.3 165.1 64.6 3.5 5.9 37.0 107.4 74.6 138.9 130.6 58.4 67.0 63.5 42.5 44.4 99.1 107.6 104.2 46.2 132.4 98.5 62.3 149.6 102.0 50.7 0.2 67.3 57.2 0.9 1.3 69.1 37.3 21.7 72.0 104.2 70.1 237.5 105.7 30.7 147.5 82.2 59.8 139.8 55.0 136.5 156.5 67.5 42.4 29.3 85.7 55.2 129.8 88.5 25.7 46.0 106.2 76.1 33.7 89.9 104.8 101.5 206.2 81.3 145.8 200.5 42.1 163.6 171.2 10.7 0.1 0.5 0.1 0.0 0.0 0.3 0.5 0.5 0.3 0.6 0.0 0.3 0.2 0.4 0.0 0.3 7.7 0.5 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.4 0.3 0.2 0.3 0.3 1.9 0.0 1.5 1.3 14.2 38.5 10.3 21.2 31.9 0.9 9.9 13.7 1.1 17.2 5.0 0.0 0.0 72.2 13.4 14.4 3.9 2.3 33.2 10.7 11.6 7.3 3.0 266.7 1.4 0.5 121.2 14.6 25.5 21.8 7.0 93.3 10.8 3.9 36.7 0.0 1.5 15.5 24.4 13.8 22.7 14.6 0.3 17.5 3.6 1.9 6.1 1.9 4.1 1.0 1.3 1.5 0.4 1.9 57.2 5.3 2.6 5.4 1.1 1.0 0.0 2.8 12.1 99.6 59.9 69.5 24.9 19.3 22.9 38.8 30.0 10.3 OCIAD1 "Asrij, FLJ20455, OCIA, TPA018" ENSG00000109180 "OCIA domain containing 1" Q9NX40 4 48805212-48861817 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044803 Approved Approved Mitochondria NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA044803: AB_10961287" "unprognostic (8.18e-2)" "unprognostic (1.60e-2)" "unprognostic (4.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.60e-1)" "unprognostic (4.10e-1)" "unprognostic (2.83e-3)" "unprognostic (1.34e-1)" "unprognostic (5.42e-2)" "unprognostic (1.47e-3)" "unprognostic (9.23e-2)" "unprognostic (2.86e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-2)" 129.5 184.0 161.1 99.4 170.6 107.7 153.9 154.6 212.9 150.3 173.5 161.1 155.8 138.0 192.2 118.1 167.2 124.6 219.3 177.3 177.0 238.1 326.5 124.1 127.3 161.1 153.1 159.1 156.1 248.7 109.9 118.4 157.6 145.9 159.9 143.7 161.9 148.1 255.0 107.1 134.6 133.3 163.1 105.1 141.3 91.0 165.8 133.6 239.4 255.9 133.9 136.3 72.3 172.6 165.2 118.2 231.7 162.8 230.8 283.0 178.6 253.1 393.8 261.1 311.3 110.6 473.2 190.4 241.5 238.0 311.4 141.7 229.4 250.4 296.2 149.4 152.7 293.4 105.7 88.1 336.5 309.1 300.9 292.0 353.5 208.3 258.4 315.4 270.0 173.9 339.8 104.1 300.0 107.7 261.4 287.6 195.2 211.7 110.4 169.6 216.9 203.1 502.9 154.5 139.8 261.0 120.4 101.1 306.5 179.8 212.8 271.5 196.9 176.1 200.7 120.7 333.1 256.3 380.4 283.1 223.2 251.0 220.2 47.8 60.2 76.5 62.6 68.0 90.8 74.1 73.1 79.2 75.4 64.9 90.2 80.5 48.3 95.4 86.5 85.2 68.5 73.5 161.1 170.6 154.6 212.9 177.3 177.0 161.1 153.1 157.6 163.1 165.8 172.6 176.7 160.3 124.5 85.8 107.1 79.7 111.3 243.3 102.4 126.6 96.7 119.6 152.3 102.9 169.4 121.4 66.7 170.5 103.1 140.0 137.0 140.0 34.3 147.3 120.5 120.2 130.1 89.8 125.1 128.3 168.8 124.4 84.1 110.5 141.8 102.6 118.9 167.3 152.7 89.2 137.2 131.3 124.1 94.0 77.2 35.5 132.3 106.1 87.2 76.8 107.2 206.1 121.5 106.1 158.1 130.7 122.5 139.2 115.3 104.2 164.1 178.9 151.2 111.6 124.9 121.3 112.7 188.3 88.3 94.1 75.9 164.7 109.8 197.2 142.7 100.4 OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 155.4" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 1277.4;Proximal enterocytes: 702.0;Proximal tubular cells: 1384.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 325.2;U-251 MG: 399.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 20: T-cells - T-cell receptor" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "HPA040979: AB_10795497, HPA041090: AB_10796236" "unprognostic (4.29e-1)" "unprognostic (2.69e-1)" "unprognostic (3.76e-2)" "prognostic favorable (7.37e-4)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (9.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-1)" "prognostic favorable (6.56e-4)" "prognostic unfavorable (6.89e-4)" "unprognostic (1.38e-1)" "prognostic favorable (2.67e-5)" "unprognostic (1.10e-1)" "unprognostic (8.54e-2)" "unprognostic (8.24e-3)" "prognostic favorable (2.34e-4)" 9.2 20.4 14.1 22.1 13.1 16.3 23.4 10.3 15.3 19.8 14.1 54.7 122.3 20.7 46.9 25.8 22.4 32.4 14.3 17.8 15.6 155.4 129.5 19.0 34.6 13.1 13.2 8.7 26.9 44.4 33.6 8.6 11.7 23.8 49.9 26.9 40.2 29.2 4.4 20.0 88.4 15.0 11.6 12.6 85.0 6.3 13.7 53.6 37.4 3.9 40.3 28.1 12.0 12.7 208.9 108.5 1.6 0.0 0.0 0.0 2.7 53.3 23.9 28.4 26.9 0.0 249.4 35.7 230.1 30.5 248.0 65.5 29.7 325.2 29.1 83.8 22.6 0.1 78.6 0.1 25.6 101.7 0.3 14.7 150.8 0.1 61.1 81.4 115.5 140.2 0.1 17.6 30.3 78.3 172.2 70.2 102.5 234.2 145.2 38.5 0.1 59.4 288.7 135.0 230.3 69.5 75.4 25.5 5.4 0.8 26.2 25.2 195.6 0.2 215.1 1.2 399.5 49.5 59.6 113.3 163.0 0.3 0.4 208.4 3.5 69.1 101.6 1.5 136.9 168.0 191.0 147.3 18.1 156.7 247.2 165.0 11.2 156.0 1.3 122.4 338.7 137.7 14.1 13.1 10.3 15.3 17.8 15.6 13.1 13.2 11.7 11.6 13.7 12.7 135.9 28.9 70.6 2.0 102.5 109.0 146.6 401.4 81.4 17.6 152.7 190.6 39.2 194.5 224.2 176.6 29.2 46.2 66.3 359.7 217.2 510.5 1.4 197.5 22.9 103.3 306.4 38.9 10.1 570.2 11.4 14.9 157.5 190.8 36.8 75.3 31.1 193.9 44.3 1.7 11.6 301.3 341.8 6.4 27.0 2.5 5.0 21.7 65.8 5.6 15.9 49.9 82.4 2.5 1.8 1277.4 311.6 21.4 53.5 180.1 702.0 1384.9 171.4 77.6 0.0 3.7 41.8 2.6 3.2 105.2 131.4 15.3 129.8 52.1 188.6 239.2 OLFML1 UNQ564 ENSG00000183801 "Olfactomedin like 1" Q6UWY5 11 7485388-7511377 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 52.3;Leydig cells: 39.7;Peritubular cells: 39.5;Sertoli cells: 26.3;Smooth muscle cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 31.2;U-2197: 20.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058824 Approved "Secreted - unknown location" NA NA 260000 "Cluster 14: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA058824: " "unprognostic (3.05e-1)" "unprognostic (5.35e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-2)" "unprognostic (5.32e-1)" "unprognostic (1.82e-3)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (7.33e-2)" "unprognostic (1.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (4.28e-8)" "unprognostic (3.13e-3)" "unprognostic (2.00e-2)" "unprognostic (3.34e-2)" "unprognostic (8.72e-3)" 21.6 6.2 1.4 5.2 1.8 0.3 12.5 2.2 1.9 27.2 7.5 8.4 5.0 19.0 21.3 8.2 17.5 23.8 14.8 1.8 1.9 6.4 10.8 18.9 9.3 2.0 1.5 48.6 2.8 2.3 3.1 7.3 1.7 14.1 10.2 0.2 5.6 18.3 5.2 8.3 7.2 18.0 1.2 14.7 5.4 4.1 2.1 3.2 8.2 12.1 5.6 14.9 17.7 2.0 0.0 0.0 0.4 0.0 1.9 1.9 31.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.2 0.1 0.1 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 6.4 0.0 0.0 0.1 0.2 0.1 20.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.1 0.2 0.0 0.8 0.1 0.0 0.0 1.4 1.8 2.2 1.9 1.8 1.9 2.0 1.5 1.7 1.2 2.1 2.0 6.1 0.0 0.0 1.0 0.4 5.2 0.0 0.0 1.2 0.1 0.2 0.3 1.0 0.0 0.6 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.3 13.3 2.9 0.0 0.0 0.1 0.0 2.0 52.3 0.0 0.4 0.0 0.0 5.0 0.9 0.6 0.0 0.1 0.0 0.0 0.0 6.1 0.7 39.7 0.4 7.2 2.8 0.0 0.0 0.0 0.5 1.4 0.1 0.0 39.5 0.2 0.1 0.0 0.3 0.0 0.0 26.3 9.4 16.3 0.3 0.1 0.2 3.7 0.3 0.7 5.0 0.0 0.1 OMD "osteoadherin, SLRR2C" ENSG00000127083 Osteomodulin Q99983 9 92412380-92424471 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fibroblasts: 66.8;Hepatic stellate cells: 26.4;Leydig cells: 97.9;Peritubular cells: 110.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "ASC diff: 6.1;ASC TERT1: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069948 Approved "Nucleoli fibrillar center,Endoplasmic reticulum" "Secreted in other tissues" NA NA 21000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA069948: AB_2732144" "unprognostic (1.18e-1)" "unprognostic (2.33e-3)" "unprognostic (5.04e-2)" "unprognostic (2.26e-1)" "unprognostic (9.42e-2)" "unprognostic (1.87e-2)" "unprognostic (4.31e-3)" "unprognostic (6.42e-2)" "unprognostic (4.53e-1)" "unprognostic (3.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-3)" "unprognostic (5.81e-3)" "unprognostic (6.35e-2)" "unprognostic (2.84e-3)" "unprognostic (2.08e-3)" 13.9 6.9 2.4 0.3 3.2 0.2 12.6 3.0 6.0 15.5 4.1 4.8 0.8 7.6 7.5 4.3 9.4 8.1 20.0 2.4 2.3 1.9 1.1 4.6 0.9 2.3 2.4 12.0 1.7 0.8 3.9 2.8 2.5 5.0 1.9 0.1 2.2 3.4 1.3 3.3 3.2 8.4 2.3 0.4 4.4 3.1 2.4 0.9 8.9 11.3 2.8 5.5 3.9 2.2 0.0 0.0 0.0 0.0 6.1 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.4 0.4 0.4 0.0 0.3 0.6 0.5 0.2 0.2 0.1 0.3 0.5 0.4 2.4 3.2 3.0 6.0 2.4 2.3 2.3 2.4 2.5 2.3 2.4 2.2 4.4 0.0 0.0 0.0 0.3 2.7 0.4 0.1 0.0 0.9 0.1 0.1 1.3 4.3 0.6 1.8 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.3 11.4 7.8 0.0 0.0 1.7 0.0 0.2 66.8 2.0 0.3 0.0 0.1 26.4 0.0 0.3 0.0 1.5 0.0 0.0 0.3 3.3 3.2 97.9 0.2 1.8 9.4 0.0 0.0 0.0 1.0 1.6 0.0 0.0 110.2 0.8 0.2 0.0 0.1 0.0 1.6 0.0 2.2 2.9 0.2 0.1 0.3 2.7 0.0 0.4 0.1 0.0 0.2 OR2W3 "OR2W3P, OR2W8P, OST718" ENSG00000238243 "Olfactory receptor family 2 subfamily W member 3" Q7Z3T1 1 247895587-247896531 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "bone marrow: 13.0;brain: 6.1;thyroid gland: 6.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.5;K-562: 4.1;PC-3: 13.2;U-2 OS: 8.4;U-937: 6.3;WM-115: 9.4" "Not detected" "Not detected" HPA045594 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "HPA045594: AB_10960280" "unprognostic (9.44e-2)" "unprognostic (3.03e-1)" "unprognostic (3.29e-2)" "unprognostic (1.57e-5)" "unprognostic (1.98e-1)" "unprognostic (5.11e-2)" "unprognostic (2.79e-6)" "unprognostic (2.71e-1)" "unprognostic (1.03e-1)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (2.71e-3)" "unprognostic (9.05e-3)" "unprognostic (9.34e-3)" "unprognostic (5.66e-2)" "unprognostic (1.48e-1)" 0.3 0.6 1.1 0.4 1.1 13.0 0.2 0.0 1.5 0.1 0.0 0.7 0.1 0.1 0.1 0.1 0.8 0.1 0.1 1.2 4.3 0.1 0.1 0.5 0.1 3.0 3.1 0.0 0.3 0.0 0.2 1.3 3.9 0.5 0.6 0.3 0.1 0.2 0.0 0.4 0.2 0.5 0.8 1.0 0.2 1.2 6.1 0.1 6.3 0.9 0.0 0.1 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 3.9 0.0 0.0 0.0 0.3 13.5 0.0 0.0 0.0 1.7 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 13.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.9 0.0 0.0 8.4 0.0 0.0 1.4 0.0 0.0 0.0 6.3 9.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.1 1.1 0.0 1.5 1.2 4.3 3.0 3.1 3.9 0.8 6.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ORMDL3 ENSG00000172057 "ORMDL sphingolipid biosynthesis regulator 3" Q8N138 17 39921041-39927601 "Disease related genes, Predicted membrane proteins" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 234.5" "Cell type enhanced" "Detected in many" "Early spermatids: 251.6;Late spermatids: 328.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 427.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (3.31e-2)" "unprognostic (6.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.55e-1)" "unprognostic (2.96e-1)" "prognostic favorable (9.29e-4)" "unprognostic (1.26e-1)" "unprognostic (3.67e-1)" "unprognostic (5.68e-2)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.37e-1)" "unprognostic (4.55e-1)" "unprognostic (1.09e-3)" "prognostic favorable (5.18e-4)" 149.0 29.6 39.6 33.9 39.5 39.7 70.8 37.2 45.8 40.1 55.9 41.9 50.0 36.1 64.7 28.4 28.0 32.4 63.0 41.7 40.2 38.0 234.5 49.0 55.9 40.9 38.6 39.9 109.6 51.1 50.2 35.5 38.3 46.9 38.6 25.1 70.4 41.6 44.2 41.4 47.8 36.6 40.1 38.3 50.0 50.8 41.6 79.4 57.7 29.5 56.4 46.9 26.3 39.1 33.5 40.2 41.8 34.8 106.1 40.2 37.9 48.0 55.4 50.5 48.4 46.1 36.3 24.7 44.6 59.4 34.5 56.0 29.8 38.6 46.9 427.6 53.2 24.1 22.5 113.0 41.5 28.5 40.6 44.2 39.7 34.9 19.7 57.2 22.8 68.5 30.9 194.8 28.0 30.1 85.1 31.9 23.4 44.2 20.1 71.2 37.7 78.4 28.2 80.1 36.6 37.2 31.8 196.6 32.9 46.3 70.8 30.8 18.7 27.4 34.0 23.6 36.8 104.2 95.3 34.5 28.2 27.6 20.6 9.3 4.7 61.1 39.4 7.7 28.3 26.4 39.3 43.3 4.2 23.1 44.2 53.7 7.7 18.4 11.6 21.1 27.7 36.6 39.6 39.5 37.2 45.8 41.7 40.2 40.9 38.6 38.3 40.1 41.6 39.1 7.6 51.3 37.2 2.9 28.7 16.4 13.7 13.1 21.6 18.5 25.9 14.5 28.9 17.2 15.3 42.3 0.0 25.9 18.4 27.3 3.9 18.4 251.6 7.2 12.6 10.3 25.9 34.1 3.4 29.2 17.9 13.9 11.2 13.8 18.4 10.5 7.5 97.8 8.3 13.5 3.8 26.8 18.3 7.5 13.0 328.9 18.6 6.0 16.0 1.9 22.1 44.9 57.7 3.5 3.2 38.8 20.8 28.6 41.2 15.2 29.2 11.9 8.0 11.2 26.3 8.5 16.5 5.8 7.6 11.5 14.3 9.3 35.6 21.0 17.7 12.4 OS9 "ERLEC2, OS-9" ENSG00000135506 "OS9 endoplasmic reticulum lectin" Q13438 12 57693955-57721557 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 7 "RH-30: 3551.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011518, HPA013694" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA 10000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011518: AB_776918, HPA013694: AB_1854812" "unprognostic (1.67e-2)" "unprognostic (4.20e-1)" "unprognostic (3.93e-2)" "unprognostic (1.50e-1)" "unprognostic (9.79e-3)" "unprognostic (1.32e-3)" "unprognostic (4.78e-2)" "unprognostic (8.54e-2)" "unprognostic (2.67e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.67e-2)" "unprognostic (4.81e-2)" "unprognostic (2.21e-2)" 151.0 93.0 61.1 118.6 59.3 149.0 113.4 60.7 60.8 135.6 94.3 158.1 149.9 101.2 141.4 105.2 109.6 106.2 111.0 58.4 71.5 114.8 264.5 130.0 89.7 64.5 62.8 124.6 270.0 171.6 71.5 141.3 63.5 116.4 132.6 75.5 189.0 102.1 59.6 119.8 143.2 110.2 60.8 106.0 137.2 38.9 66.7 72.6 129.4 65.5 94.2 119.7 103.5 63.7 86.8 170.8 86.2 214.4 440.4 295.6 190.5 211.9 268.4 153.4 154.6 180.2 274.5 110.0 345.3 255.2 118.5 152.9 81.3 137.5 121.2 142.0 97.6 124.0 115.3 164.8 287.1 196.9 307.3 273.7 217.6 150.7 152.6 529.4 258.6 71.7 96.0 427.9 162.2 149.5 53.7 239.7 97.7 172.0 121.2 69.8 3551.9 281.5 116.5 210.6 88.4 116.4 300.3 205.5 176.6 158.1 245.4 381.0 238.9 206.0 122.3 140.4 136.4 253.4 234.6 112.9 173.8 141.6 290.4 175.7 241.2 274.6 72.9 213.0 68.5 50.5 61.1 65.0 172.6 54.3 46.8 54.1 246.4 58.8 182.4 149.0 74.4 218.9 61.1 59.3 60.7 60.8 58.4 71.5 64.5 62.8 63.5 60.8 66.7 63.7 83.3 86.6 116.7 22.2 65.8 57.7 85.4 103.3 43.9 44.1 61.2 46.6 14.1 80.1 111.8 73.5 77.2 142.4 64.5 153.0 9.8 144.8 6.7 34.0 73.3 90.2 103.6 53.4 19.5 110.1 124.6 113.6 65.7 60.0 91.1 61.6 81.4 161.1 144.8 50.5 27.0 167.3 107.8 121.1 99.1 10.7 113.4 106.1 119.2 29.0 125.0 87.2 53.5 23.6 24.4 94.7 155.4 79.0 141.1 56.5 154.0 53.9 74.0 50.9 92.1 68.3 66.9 38.1 46.4 51.3 51.6 197.7 59.5 64.9 102.4 65.0 OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.7;retina: 160.8" "Cell type enhanced" "Detected in many" "Early spermatids: 135.4;Excitatory neurons: 132.8;Inhibitory neurons: 156.3;Late spermatids: 304.4;Oligodendrocytes: 182.8;Rod photoreceptor cells: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.9;HeLa: 146.4;hTERT-HME1: 38.2;SiHa: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA021514: AB_1854813" "unprognostic (2.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (6.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-5)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "prognostic favorable (3.79e-6)" "unprognostic (9.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" 1.4 11.8 6.2 2.8 14.4 52.7 1.5 17.0 20.5 1.6 2.1 1.7 7.5 2.0 14.6 3.7 2.0 3.0 12.2 8.5 4.4 2.6 1.0 1.6 2.3 9.6 9.8 1.6 5.0 9.3 20.9 4.6 10.0 2.3 1.7 160.8 2.9 2.4 2.8 5.4 5.6 1.2 1.8 4.8 3.5 28.7 21.3 0.6 3.2 3.2 1.3 4.4 2.1 15.1 7.1 15.4 1.5 6.7 1.0 5.8 1.6 1.3 3.1 4.8 4.8 14.0 3.9 12.5 5.7 1.9 1.5 4.1 6.2 0.6 3.5 6.7 1.8 41.9 146.4 2.7 0.9 0.2 2.5 0.3 16.8 11.8 38.2 1.6 12.1 4.8 26.7 0.5 11.0 7.8 1.3 4.5 3.8 3.3 13.8 3.5 0.5 0.7 0.6 2.7 16.7 6.8 39.2 4.1 0.4 2.9 4.9 2.2 8.8 3.4 18.1 3.2 6.8 3.2 4.8 2.3 13.3 0.0 2.7 0.0 0.7 0.4 0.5 1.1 1.0 0.5 1.0 0.4 0.6 0.6 1.0 1.1 0.7 1.0 0.9 0.2 0.7 2.0 6.2 14.4 17.0 20.5 8.5 4.4 9.6 9.8 10.0 1.8 21.3 15.1 1.2 0.0 3.1 37.9 0.2 5.2 0.9 0.4 0.6 93.2 1.3 0.8 11.2 2.8 1.0 1.8 81.3 0.2 0.3 1.3 1.9 1.8 135.4 1.6 0.5 2.8 7.2 91.3 132.8 1.5 0.2 1.6 2.0 1.6 0.0 3.2 0.4 0.1 0.2 18.5 156.3 2.8 0.0 0.3 1.8 304.4 2.5 1.7 1.8 8.4 0.4 31.4 0.0 35.7 182.8 0.8 5.2 1.9 1.4 1.2 0.7 0.8 1.3 619.5 0.0 1.1 2.3 48.6 4.4 1.4 9.5 0.3 0.5 1.2 1.2 1.3 OSCP1 "C1orf102, NOR1" ENSG00000116885 "Organic solute carrier partner 1" Q8WVF1 1 36415827-36450451 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 58.0;testis: 76.1" "Cell type enhanced" "Detected in many" "Early spermatids: 453.5;Endometrial ciliated cells: 88.6;Respiratory ciliated cells: 199.1;Spermatocytes: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028436, HPA052655" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA028436: AB_10600885, HPA052655: " "unprognostic (3.46e-3)" "unprognostic (7.57e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.88e-4)" "unprognostic (1.28e-2)" "unprognostic (4.81e-2)" "unprognostic (3.38e-2)" "unprognostic (4.52e-2)" "unprognostic (5.52e-2)" "unprognostic (8.80e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.20e-1)" "unprognostic (2.04e-2)" "unprognostic (1.02e-2)" "unprognostic (4.20e-2)" 6.8 8.2 9.7 2.4 10.4 2.0 9.4 7.4 10.5 9.5 31.3 7.3 2.9 10.0 22.0 5.0 58.0 8.8 7.9 11.1 13.0 19.1 2.8 11.0 1.9 11.3 14.7 9.1 8.2 30.2 23.1 5.6 10.9 9.9 3.9 23.1 8.7 8.9 4.9 6.8 2.7 7.9 9.9 1.4 6.3 76.1 13.5 3.6 17.9 5.2 1.5 5.9 4.8 8.3 6.7 6.3 7.6 8.9 8.9 8.6 1.4 4.0 9.7 9.7 6.6 0.1 5.8 1.5 7.3 7.3 7.1 5.1 0.2 7.5 6.2 1.1 5.9 0.1 3.9 0.7 10.9 0.8 1.2 9.8 12.0 13.7 5.9 14.1 6.7 6.3 0.1 1.7 7.7 4.8 3.6 2.5 7.8 2.6 2.6 3.8 3.1 1.2 16.0 2.3 20.4 9.0 7.5 3.5 5.4 7.2 7.6 1.1 5.8 7.0 2.6 12.7 6.9 2.8 3.1 0.8 13.4 0.2 4.7 0.0 0.2 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.6 0.2 0.6 1.0 0.1 0.1 0.0 1.2 0.7 0.2 9.7 10.4 7.4 10.5 11.1 13.0 11.3 14.7 10.9 9.9 13.5 8.3 3.0 9.6 10.9 4.6 0.4 1.5 5.5 21.3 3.4 5.4 7.9 7.5 5.5 5.7 21.3 12.9 16.7 12.2 0.0 2.0 23.5 15.1 453.5 88.6 5.8 3.3 4.9 1.7 8.1 9.3 3.4 6.4 6.1 7.7 0.0 4.8 2.2 2.3 4.2 5.0 6.9 2.3 32.6 0.8 1.2 66.8 12.5 1.4 3.6 1.0 0.1 12.9 0.0 5.0 2.6 7.2 4.0 9.1 0.4 3.5 0.5 26.1 199.1 21.3 0.0 4.7 7.7 163.7 20.6 3.6 3.1 20.1 0.7 13.9 2.3 5.2 OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 43.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Oligodendrocytes: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: AB_1854847, HPA076357: " "unprognostic (2.17e-2)" "unprognostic (2.93e-2)" "unprognostic (1.90e-1)" "prognostic favorable (7.47e-4)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (1.23e-3)" "unprognostic (1.46e-2)" "prognostic favorable (5.09e-5)" "unprognostic (4.90e-2)" "unprognostic (7.72e-2)" "unprognostic (8.94e-2)" "unprognostic (3.37e-2)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (1.58e-2)" 11.7 7.7 21.0 3.8 39.2 1.1 7.8 28.7 18.5 9.9 6.8 7.6 6.2 10.5 3.8 7.7 9.3 4.8 7.1 15.3 22.1 5.6 10.7 7.3 1.9 41.4 37.2 10.9 6.1 10.9 3.4 7.1 35.5 6.6 7.1 10.1 7.8 7.5 18.6 5.8 6.2 10.8 27.9 3.6 6.7 12.7 31.7 2.1 6.7 16.2 3.2 6.3 5.2 43.0 17.2 13.5 9.3 15.6 12.0 11.1 8.8 11.8 17.3 14.0 9.6 10.0 13.6 0.2 7.5 21.7 6.3 13.4 13.2 13.1 14.6 16.5 6.7 6.6 18.9 6.8 12.8 7.6 6.9 12.4 9.9 23.7 20.6 10.9 11.5 2.0 18.4 18.1 10.1 17.5 1.3 2.1 11.9 12.8 13.1 1.8 12.9 4.4 5.4 23.2 6.0 11.4 20.8 15.2 18.5 12.1 12.6 4.0 13.9 14.4 13.2 9.8 14.0 19.1 20.0 2.0 12.8 2.2 24.1 2.0 0.0 0.4 0.7 0.0 0.5 0.1 0.3 0.4 0.0 0.1 0.2 0.3 0.3 0.4 0.0 0.1 0.1 0.0 21.0 39.2 28.7 18.5 15.3 22.1 41.4 37.2 35.5 27.9 31.7 43.0 10.2 35.3 11.7 56.8 3.0 15.9 22.7 8.7 13.1 28.0 18.3 9.3 22.2 12.8 15.3 11.0 106.3 23.5 5.1 41.1 7.9 14.5 63.4 21.8 17.8 16.7 17.4 14.9 20.6 11.1 11.6 14.8 21.4 40.2 0.0 22.0 20.3 33.0 3.1 23.5 24.6 15.8 8.2 0.8 5.9 79.4 14.6 2.4 37.4 22.5 4.3 23.6 15.5 33.2 176.8 20.6 21.3 23.0 4.7 20.2 17.1 11.5 17.4 66.9 0.0 19.8 17.9 11.1 7.2 11.8 16.6 21.2 7.5 11.1 11.1 34.0 PADI4 "PAD, PADI5, PDI4, PDI5" ENSG00000159339 "Peptidyl arginine deiminase 4" Q9UM07 1 17308195-17364004 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "bone marrow: 105.1;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in some" "dendritic cells: 8.3;granulocytes: 12.6;Macrophages: 14.6;monocytes: 22.3;NK-cells: 20.6" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "basophil: 79.9;classical monocyte: 71.3;eosinophil: 97.5;neutrophil: 183.0" "Group enriched" "Detected in all" 9 "granulocytes: 183.0;monocytes: 71.3" "Cell line enhanced" "Detected in some" "HEL: 1.2;RPMI-8226: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017007, HPA042825" Enhanced NA NA 29000 "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA017007: AB_1854921, HPA042825: AB_2678189" "unprognostic (1.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (1.13e-2)" "unprognostic (1.47e-1)" "unprognostic (4.91e-2)" "unprognostic (8.49e-2)" "unprognostic (5.22e-2)" "unprognostic (8.55e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-3)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-2)" "unprognostic (1.80e-1)" 1.8 0.1 0.2 0.7 0.4 105.1 0.3 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.4 1.0 0.4 1.1 0.3 0.2 0.5 1.7 7.9 0.3 0.3 0.1 0.1 0.3 0.0 0.2 0.5 0.3 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.4 0.0 29.9 0.4 0.1 0.1 1.6 0.3 0.3 0.2 0.7 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 79.9 71.3 97.5 0.4 5.7 0.2 1.1 0.5 0.7 13.9 1.8 2.6 4.5 183.0 4.5 1.8 6.2 0.4 35.8 0.2 0.4 0.2 0.8 0.3 0.2 0.3 0.1 0.3 0.0 0.1 0.4 0.0 0.0 3.7 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.6 0.0 0.6 0.6 0.0 0.0 12.6 0.1 0.0 0.4 0.2 0.0 0.4 0.0 0.0 3.3 0.4 0.2 0.0 14.6 0.0 0.0 22.3 0.0 20.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 4.0 0.0 0.0 0.1 2.3 0.1 0.0 0.0 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 23.1 34.3 35.1 21.2 42.2 41.2 20.6 43.9 45.0 20.8 28.4 21.7 22.4 23.8 22.7 23.9 20.9 19.9 28.2 33.9 45.4 25.3 23.8 21.7 20.7 47.6 45.0 23.3 20.3 21.9 24.5 25.4 51.0 22.3 20.0 23.2 17.4 16.1 15.7 22.0 19.4 20.4 48.7 20.4 23.0 30.0 43.6 21.5 31.9 20.3 22.2 26.9 20.9 51.6 43.4 48.5 54.9 79.7 60.1 41.7 42.6 71.0 61.7 38.8 35.2 89.2 92.9 46.6 99.4 85.8 38.7 67.7 80.6 92.0 50.9 41.8 31.1 120.0 41.3 57.9 53.8 42.1 44.0 46.6 71.7 77.4 96.7 42.4 64.8 25.6 65.0 34.6 60.3 27.7 40.8 61.7 50.4 60.0 37.8 44.9 62.2 51.2 59.8 66.7 60.9 80.5 82.2 61.6 28.1 46.6 68.4 35.6 103.8 70.4 46.3 34.8 51.4 10.8 17.9 61.5 28.3 78.8 60.4 63.4 51.4 48.6 39.0 58.7 46.4 43.8 44.7 41.0 37.4 41.2 45.8 49.2 63.7 33.1 66.3 27.4 35.1 53.1 35.1 42.2 43.9 45.0 33.9 45.4 47.6 45.0 51.0 48.7 43.6 51.6 48.5 28.9 34.8 17.9 41.4 122.4 44.5 45.9 54.7 38.6 55.4 32.1 37.6 58.6 32.8 66.2 47.9 40.4 44.4 48.0 46.9 61.3 13.1 63.6 54.8 64.8 82.6 39.4 29.2 39.5 86.7 40.8 33.6 78.4 19.0 36.8 79.6 47.0 43.0 47.1 32.5 41.8 36.7 65.4 175.9 13.7 45.4 52.1 49.8 20.6 59.3 36.2 21.6 13.0 61.2 99.0 50.5 34.3 28.9 67.0 33.7 54.8 32.9 38.3 13.1 42.8 40.0 54.7 84.7 53.2 115.9 54.6 41.6 35.2 45.4 50.6 PAFAH2 HSD-PLA2 ENSG00000158006 "Platelet activating factor acetylhydrolase 2" Q99487 1 25959767-25998117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.7" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018157 Approved NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA018157: AB_1854928" "unprognostic (9.89e-2)" "unprognostic (2.60e-1)" "unprognostic (3.63e-3)" "prognostic favorable (3.28e-6)" "unprognostic (5.19e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-1)" "unprognostic (4.46e-2)" "unprognostic (2.62e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.15e-2)" "unprognostic (8.17e-2)" "unprognostic (1.59e-2)" "unprognostic (7.27e-2)" 4.6 7.3 4.7 6.5 6.5 6.8 9.2 6.3 6.0 8.8 6.7 16.3 17.4 4.9 9.9 7.8 8.3 10.4 9.7 4.5 5.8 19.3 18.3 8.6 8.4 6.4 6.5 4.7 31.2 22.9 5.9 9.2 6.5 8.8 16.6 14.1 10.0 6.3 18.0 11.4 19.0 6.9 5.5 7.6 15.6 7.7 6.5 48.7 16.4 10.7 7.4 7.0 5.5 8.2 8.6 10.7 6.7 7.6 13.9 10.9 13.7 9.6 5.0 8.6 5.7 4.4 18.1 3.8 11.7 5.7 8.1 7.5 10.1 9.3 11.0 7.8 6.1 6.3 4.6 8.8 8.4 3.3 52.5 7.2 21.2 13.2 8.7 4.7 8.3 8.9 8.9 7.1 11.7 3.8 10.3 3.3 13.4 29.9 5.9 8.4 6.3 8.7 13.9 3.0 8.0 6.8 5.7 7.7 18.2 11.0 12.7 6.0 7.8 5.9 7.4 12.5 7.7 13.0 18.1 4.8 12.5 13.2 20.0 36.2 6.7 60.2 23.7 6.4 15.3 3.5 8.3 15.4 5.0 4.4 10.6 14.9 5.8 17.4 2.4 39.0 9.0 8.7 4.7 6.5 6.3 6.0 4.5 5.8 6.4 6.5 6.5 5.5 6.5 8.2 4.6 16.0 12.8 9.8 3.2 1.5 2.1 5.3 1.8 9.5 9.4 4.8 6.8 11.5 11.9 18.4 27.1 11.2 37.7 34.9 3.9 11.1 1.1 8.6 4.5 5.6 7.8 3.2 4.0 7.3 9.5 3.5 12.2 13.2 27.8 7.3 5.7 21.4 11.2 5.0 3.6 18.2 4.1 11.6 1.6 1.0 2.5 7.1 8.8 5.6 7.3 6.3 23.7 4.0 10.0 10.6 15.8 2.6 6.5 4.2 43.1 18.3 8.9 8.8 6.6 5.3 4.1 19.9 8.9 4.5 3.8 10.0 9.0 4.4 19.4 4.9 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "classical monocyte: 182.2;eosinophil: 292.7;intermediate monocyte: 177.7;myeloid DC: 264.3;neutrophil: 431.8;non-classical monocyte: 202.6" "Group enriched" "Detected in all" 11 "dendritic cells: 264.3;granulocytes: 431.8;monocytes: 202.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 560000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 12.7 13.4 32.4 33.9 44.5 59.0 18.2 13.9 57.7 21.1 0.0 43.2 43.1 20.9 29.8 21.4 21.9 30.9 9.4 58.3 8.0 26.1 14.5 16.8 20.4 19.2 12.2 21.1 17.5 20.5 20.7 14.7 19.4 19.1 46.5 25.1 19.9 19.7 87.0 16.2 45.7 27.0 0.9 29.3 41.2 25.7 17.1 29.1 40.6 18.8 23.1 27.7 20.7 30.0 39.9 26.7 56.7 25.5 22.8 37.6 45.9 44.6 32.1 42.0 48.7 38.7 52.8 36.3 16.0 39.4 54.4 20.2 40.2 47.8 65.5 41.4 32.6 38.2 17.6 2.3 15.3 64.3 53.5 28.2 28.8 49.2 73.1 36.6 10.1 41.3 25.5 61.2 77.6 2.9 42.3 30.2 84.5 166.2 22.5 62.6 72.3 1.4 10.6 32.9 24.6 23.9 23.6 9.7 19.5 55.0 45.4 29.0 0.9 27.3 47.5 148.9 37.9 165.7 92.4 23.4 23.0 42.5 30.6 2.5 182.2 292.7 11.2 177.7 9.4 16.8 8.4 10.7 264.3 12.9 7.4 14.5 431.8 28.4 202.6 22.9 7.3 92.3 32.4 44.5 13.9 57.7 58.3 8.0 19.2 12.2 19.4 0.9 17.1 30.0 3.1 3.2 20.5 24.2 23.9 11.9 33.3 28.2 23.9 51.6 25.1 19.7 6.2 35.8 30.8 25.8 8.4 25.4 10.2 78.6 45.0 32.4 38.8 37.3 13.5 3.2 37.8 30.5 219.1 56.3 53.5 24.0 45.9 39.7 132.2 35.2 3.6 11.4 49.8 1.7 118.5 50.8 28.5 59.6 152.9 28.3 14.3 80.0 30.2 54.4 121.7 14.9 10.3 53.3 70.7 50.9 57.9 13.2 28.6 28.7 47.9 55.7 39.0 6.4 13.1 13.8 25.2 50.4 53.8 23.6 10.4 95.0 19.3 10.3 52.8 33.2 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.9;pancreas: 42.7;pituitary gland: 13.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 104.1;Excitatory neurons: 364.0;Inhibitory neurons: 323.5;Oligodendrocyte precursor cells: 165.9;Peritubular cells: 81.3" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Cell line enhanced" "Detected in some" "EFO-21: 10.8;HAP1: 9.9;HDLM-2: 12.4;NTERA-2: 9.7;SCLC-21H: 12.4;SH-SY5Y: 7.7;U-2197: 7.6;U-251 MG: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 1.0 5.2 16.9 1.6 16.2 0.1 5.2 0.0 17.6 2.3 0.0 0.7 0.2 5.4 5.8 0.7 2.5 1.6 0.3 17.8 31.9 0.7 0.2 0.9 1.7 1.6 0.0 6.2 42.7 0.1 13.7 0.6 6.0 3.4 0.7 7.0 2.2 4.8 1.6 1.3 0.5 4.7 0.4 2.0 2.0 2.6 13.2 0.6 6.2 0.4 0.8 0.9 0.7 2.8 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 0.0 0.0 10.8 1.2 1.6 0.0 9.9 0.6 1.3 12.4 0.4 0.0 1.3 0.0 0.0 0.0 0.4 0.3 0.0 0.1 2.2 5.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 9.7 0.0 2.2 0.1 4.3 0.0 0.8 0.0 12.4 7.7 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.7 4.7 7.6 13.6 0.1 0.1 0.1 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 16.2 0.0 17.6 17.8 31.9 1.6 0.0 6.0 0.4 13.2 2.8 0.9 3.2 1.1 16.0 0.6 0.3 13.3 0.2 0.0 104.1 6.9 10.4 1.0 20.0 0.7 0.0 0.0 0.3 0.2 0.2 0.0 4.7 4.4 1.0 10.8 2.3 3.6 0.0 364.0 13.1 0.4 10.3 10.2 1.7 1.3 21.9 1.4 0.2 0.2 6.7 323.5 0.3 0.0 0.3 5.7 7.0 34.2 1.1 0.0 17.8 0.7 27.5 1.0 165.9 12.0 5.3 0.0 81.3 1.0 1.7 0.0 0.6 0.0 6.0 0.0 1.6 7.8 1.4 1.4 0.3 1.1 6.7 2.4 29.2 0.3 0.9 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.6;skin 1: 28.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;NK-cells: 16.5;Suprabasal keratinocytes: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.5;HaCaT: 32.2;hTCEpi: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.2 8.2 11.6 0.4 15.9 0.9 2.1 8.5 16.6 4.5 0.0 1.3 1.5 0.9 1.0 25.6 4.3 1.1 8.3 17.6 3.0 4.7 0.3 2.5 0.9 1.4 1.1 0.6 8.0 8.0 12.1 7.6 1.9 4.4 1.1 0.8 6.1 3.8 4.5 28.2 1.5 0.3 1.8 0.9 3.9 17.7 3.0 0.5 7.5 1.3 1.9 3.5 9.4 5.4 3.9 0.0 0.2 0.0 0.0 0.0 6.0 0.0 0.2 0.7 0.7 26.5 2.9 0.1 3.6 0.0 1.3 32.2 4.5 6.9 0.3 0.2 1.0 0.0 3.0 0.2 0.0 0.1 0.3 0.0 19.4 0.3 4.5 0.2 0.0 5.5 1.8 0.3 0.0 4.5 0.0 0.5 0.5 3.9 2.9 0.2 0.2 2.9 1.5 8.4 7.3 2.0 2.6 10.9 0.3 1.7 1.7 10.3 0.0 0.3 0.6 0.0 0.3 0.1 0.3 0.1 0.7 0.6 0.2 1.2 0.1 1.2 2.3 0.1 0.8 0.6 0.1 1.9 0.3 0.1 0.1 0.4 0.5 0.9 0.1 0.1 0.0 0.6 11.6 15.9 8.5 16.6 17.6 3.0 1.4 1.1 1.9 1.8 3.0 5.4 0.0 0.0 4.2 0.7 0.3 9.8 9.6 4.8 8.6 3.5 2.8 2.9 0.0 4.3 5.4 5.5 0.0 52.7 2.1 0.3 13.7 4.4 8.6 3.3 0.4 0.3 4.9 0.0 8.9 4.3 3.0 0.7 0.5 5.1 0.0 0.7 0.0 0.0 4.1 0.0 7.3 1.1 2.0 0.6 0.9 5.8 1.8 0.3 1.8 1.0 0.0 1.3 16.5 0.5 0.3 2.5 1.0 1.9 0.1 5.2 0.2 0.2 3.9 0.2 0.0 0.3 0.4 1.9 3.3 13.9 19.0 9.0 1.0 0.8 2.0 11.3 PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004190, CAB005870" Supported Supported Nucleoplasm,Cytosol NA NA 35000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytosol" "CAB005870: AB_444361, HPA004190: AB_1079566" "unprognostic (6.88e-3)" "unprognostic (7.50e-2)" "unprognostic (3.48e-2)" "unprognostic (1.16e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (7.45e-2)" "unprognostic (9.63e-2)" "unprognostic (2.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-3)" "unprognostic (8.17e-2)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (7.43e-2)" 249.4 373.6 283.5 213.7 290.0 205.0 235.7 292.9 403.4 201.1 327.7 252.5 145.8 212.2 278.0 161.0 203.2 162.9 388.0 285.5 296.6 311.0 397.6 181.6 269.2 289.6 286.0 234.2 308.5 387.6 283.6 174.1 291.7 234.9 194.9 273.8 240.9 185.6 771.4 127.1 170.5 199.1 295.2 188.2 234.2 139.6 288.1 217.9 286.3 541.8 249.7 226.5 171.2 299.7 537.0 452.5 467.1 523.2 459.8 442.6 218.4 476.7 434.4 450.4 360.3 419.9 549.4 633.1 534.2 505.1 328.6 367.1 483.2 625.3 579.3 574.5 526.2 683.0 678.6 674.5 403.8 662.9 418.6 421.3 262.4 459.8 547.4 359.2 478.2 340.1 676.8 471.7 633.0 485.0 474.3 868.7 376.1 653.6 465.4 366.7 598.0 888.7 714.7 269.7 527.7 447.4 470.4 728.0 798.4 370.1 414.9 503.7 459.3 412.8 344.6 395.5 539.5 452.8 788.4 938.8 551.5 1002.9 606.4 298.4 590.2 394.0 484.7 553.7 459.2 483.6 478.2 577.3 717.4 374.6 406.8 466.8 202.5 551.1 456.9 1378.2 874.4 1060.8 283.5 290.0 292.9 403.4 285.5 296.6 289.6 286.0 291.7 295.2 288.1 299.7 243.6 131.4 157.1 23.2 211.8 208.9 402.4 677.7 200.9 196.2 342.0 381.8 453.3 257.4 318.5 248.3 79.2 553.0 382.3 131.1 851.0 504.3 32.1 272.1 263.9 241.7 238.0 177.1 19.5 478.4 612.1 302.3 146.3 195.9 206.5 291.2 183.1 368.1 435.1 186.7 22.9 279.6 484.2 204.5 304.5 53.6 358.2 258.9 359.3 21.5 605.4 816.4 327.5 18.1 36.0 378.9 186.9 378.7 269.7 523.4 227.1 941.5 327.8 235.5 276.1 277.8 342.6 288.2 302.2 220.4 143.8 469.6 244.4 535.3 312.2 433.1 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 PCCA ENSG00000175198 "Propionyl-CoA carboxylase subunit alpha" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 218.2" "Cell type enhanced" "Detected in all" "Astrocytes: 152.8;Excitatory neurons: 152.8;Inhibitory neurons: 166.5;Microglial cells: 217.4;Oligodendrocyte precursor cells: 200.6;Oligodendrocytes: 182.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 167.0;SCLC-21H: 91.1;U-937: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 290000 "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA041716: AB_2677635, HPA047792: AB_2680156" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-3)" "unprognostic (2.41e-1)" "unprognostic (1.55e-1)" "unprognostic (6.14e-2)" "unprognostic (1.42e-1)" "prognostic favorable (0.00e+0)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (1.18e-1)" "unprognostic (9.32e-2)" 35.4 56.3 29.0 12.4 29.8 6.2 25.8 55.5 34.6 22.3 44.4 37.5 13.2 14.9 218.2 19.4 17.4 11.6 35.4 28.6 26.3 111.7 104.3 12.0 8.0 28.9 27.4 19.9 27.6 25.7 12.3 21.3 31.1 25.9 27.6 25.2 26.9 16.9 17.6 18.6 18.0 13.7 30.3 17.2 40.9 9.2 33.9 11.4 20.4 27.2 6.4 21.3 17.5 38.7 10.6 18.5 29.8 9.9 27.9 24.2 16.6 10.2 15.4 9.5 9.0 23.0 13.9 0.8 15.2 10.1 12.0 11.8 9.1 14.1 15.6 17.5 10.1 24.6 12.7 49.7 15.4 1.2 11.3 22.4 15.2 8.8 14.6 23.0 19.6 13.0 9.8 13.4 17.1 11.6 2.6 54.8 18.6 37.2 8.1 21.4 12.9 17.3 167.0 20.5 91.1 10.9 7.0 38.4 17.9 31.9 27.9 43.1 14.3 9.6 8.0 6.7 7.3 13.1 12.9 0.4 18.4 131.6 6.9 1.6 9.1 1.7 4.5 11.2 5.9 3.6 2.8 4.2 13.5 2.3 3.9 4.9 1.1 8.7 12.3 1.1 6.5 5.2 29.0 29.8 55.5 34.6 28.6 26.3 28.9 27.4 31.1 30.3 33.9 38.7 11.3 3.2 8.7 152.8 6.6 1.9 29.1 12.7 8.6 15.5 13.5 8.8 10.5 52.9 14.8 20.2 29.2 25.7 4.3 20.7 99.7 19.7 17.6 76.5 22.4 12.0 3.6 3.4 152.8 8.4 6.9 12.9 12.2 72.9 14.0 20.7 12.1 48.8 11.8 28.6 166.5 12.4 12.2 14.2 2.2 12.0 8.7 8.2 5.4 217.4 6.0 11.5 10.3 200.6 182.5 5.8 17.5 13.5 9.4 11.2 13.2 86.9 13.2 31.7 13.1 12.3 10.1 7.2 6.2 10.6 3.8 30.2 6.4 17.6 27.6 19.2 PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749443-149811420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1022.2;Late spermatids: 428.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 4100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA003239: AB_1079580" "prognostic unfavorable (4.02e-7)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.35e-2)" "prognostic unfavorable (4.27e-4)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.88e-4)" "prognostic unfavorable (2.58e-4)" "unprognostic (1.91e-2)" "unprognostic (1.58e-2)" "unprognostic (9.02e-2)" "unprognostic (6.45e-2)" "unprognostic (6.77e-2)" "unprognostic (6.14e-2)" "unprognostic (4.38e-1)" "unprognostic (1.70e-1)" "unprognostic (2.17e-2)" "prognostic unfavorable (6.38e-4)" 48.7 43.2 77.5 32.8 85.1 75.9 46.2 70.2 107.1 46.4 56.4 45.5 36.6 38.8 48.5 45.3 39.2 28.4 121.7 87.5 84.8 51.1 73.8 37.9 41.4 80.3 73.0 39.3 38.1 46.3 43.3 42.9 86.2 52.1 43.1 55.8 39.8 50.1 211.9 44.6 34.6 48.9 71.1 34.5 37.8 76.7 72.3 57.4 49.0 163.3 46.7 40.7 38.0 79.2 87.3 68.4 70.4 88.6 152.1 125.9 77.6 140.7 82.9 114.7 143.4 200.1 65.4 117.9 113.0 127.5 126.5 106.6 123.9 143.6 159.9 79.2 180.0 175.5 122.2 192.1 99.2 203.7 197.7 62.8 105.2 128.5 138.5 80.7 107.6 89.8 256.5 107.7 142.3 258.9 98.5 150.4 56.5 84.7 78.6 83.4 89.7 82.6 108.9 62.4 137.5 52.4 111.2 173.9 97.7 82.5 107.8 146.1 83.3 67.2 80.7 124.7 151.2 64.1 109.9 115.4 103.6 135.8 137.7 162.9 193.2 178.0 93.0 182.4 94.7 105.0 93.7 102.8 176.0 81.5 86.5 98.0 101.6 108.5 185.7 79.9 129.2 204.1 77.5 85.1 70.2 107.1 87.5 84.8 80.3 73.0 86.2 71.1 72.3 79.2 57.0 54.5 41.4 21.2 62.6 175.1 74.4 204.4 56.3 72.6 48.0 40.6 154.1 60.1 96.4 79.1 37.5 169.3 66.8 56.6 78.2 113.5 1022.2 51.9 58.4 69.8 55.2 170.1 77.0 110.7 214.0 79.2 26.0 48.8 107.7 38.8 53.9 115.6 119.1 65.6 52.8 72.9 187.2 78.7 127.5 428.1 71.7 78.2 138.7 31.9 143.7 121.2 74.2 30.7 72.2 106.6 57.9 73.7 71.8 67.8 65.1 89.3 106.2 66.3 111.7 64.0 110.4 224.9 96.3 60.7 157.6 148.3 83.0 55.0 58.7 59.1 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018469: AB_1855116, HPA027094: AB_10601387" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.32e-2)" "unprognostic (5.07e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.07e-5)" "unprognostic (1.44e-1)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (8.22e-2)" "prognostic favorable (4.23e-4)" 20.8 22.0 19.1 27.1 21.6 22.9 23.0 21.6 24.3 18.9 16.6 27.3 17.0 24.1 37.2 36.8 22.5 21.3 30.6 18.4 21.3 28.4 18.5 18.4 25.3 21.8 24.7 21.1 11.4 23.4 10.5 23.4 21.7 27.0 28.9 21.1 16.9 23.2 58.8 36.8 17.3 38.6 20.8 17.0 17.6 22.8 22.1 22.4 21.4 34.3 34.0 33.1 17.5 22.2 41.8 58.7 59.9 52.2 19.3 27.4 67.5 51.3 32.5 92.9 58.1 74.2 25.5 68.6 74.0 62.3 122.3 34.2 76.0 50.2 74.0 110.6 65.8 72.0 31.8 89.7 50.8 77.3 73.2 29.8 92.0 82.0 52.3 24.2 58.9 52.8 61.1 43.8 70.7 74.6 75.8 117.7 77.9 45.6 86.6 72.5 63.2 48.0 58.2 98.7 55.9 49.6 41.0 54.7 59.0 48.6 42.3 53.0 45.8 56.4 60.1 44.8 72.2 26.4 54.1 68.3 34.4 90.5 45.7 82.3 64.8 80.2 63.1 124.4 72.8 92.5 95.0 70.4 114.9 78.1 97.7 75.4 7.0 93.9 161.7 64.0 113.6 87.3 19.1 21.6 21.6 24.3 18.4 21.3 21.8 24.7 21.7 20.8 22.1 22.2 37.4 19.2 25.2 1.6 39.5 65.6 36.6 79.2 52.9 13.0 24.8 36.2 40.9 18.6 46.1 14.7 6.2 70.8 61.5 16.0 60.7 50.6 37.0 38.9 26.6 30.2 19.8 21.7 2.3 39.1 51.2 22.6 19.4 34.6 92.9 25.4 12.5 17.0 59.7 11.8 2.0 24.0 89.5 17.8 80.7 14.3 14.6 54.4 35.6 3.7 104.3 19.7 40.2 2.0 4.5 31.8 18.6 33.4 27.7 33.2 19.7 77.9 28.1 16.5 52.6 23.8 54.1 5.5 66.9 63.2 57.5 52.4 91.8 24.5 31.3 32.4 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746410-43773278 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1048.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" NA NA 200000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB011199: AB_609902, CAB015181: AB_2160857, CAB075744: AB_2665750, HPA002645: AB_1079031, HPA003230: AB_1079030" "unprognostic (9.20e-2)" "unprognostic (1.21e-3)" "unprognostic (1.34e-1)" "prognostic favorable (2.05e-4)" "unprognostic (2.40e-2)" "prognostic unfavorable (8.95e-5)" "unprognostic (1.67e-1)" "unprognostic (8.60e-2)" "unprognostic (2.65e-1)" "unprognostic (2.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.11e-8)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (6.63e-2)" 17.0 16.6 7.5 16.5 8.0 27.1 15.6 9.2 7.6 24.7 13.9 20.6 23.6 16.4 44.7 18.9 15.4 13.5 17.3 7.7 9.8 15.3 34.5 16.8 18.7 9.3 8.2 16.5 36.0 22.6 16.2 23.8 9.1 25.2 22.5 8.4 21.6 19.1 7.6 17.3 21.4 17.0 9.0 12.5 20.4 10.8 9.3 9.6 56.0 4.1 12.3 15.6 15.2 9.8 29.4 11.9 24.6 55.1 48.9 51.9 70.8 58.6 62.1 46.0 56.7 33.6 32.1 33.8 37.4 72.9 30.8 47.8 31.8 61.5 39.7 24.3 44.7 47.2 17.6 30.9 80.1 26.0 33.8 33.6 49.8 35.0 58.5 54.0 81.3 11.1 27.7 17.4 45.5 11.1 9.1 30.4 24.4 48.5 44.0 17.9 36.7 26.2 39.3 26.0 22.9 25.4 48.7 49.0 19.4 25.0 33.1 28.1 50.9 37.7 18.9 29.7 29.1 7.1 8.6 33.9 48.1 41.2 28.8 11.6 8.8 13.3 12.1 9.2 12.8 5.4 6.8 9.5 8.3 6.1 6.0 7.1 2.4 12.7 9.9 17.6 5.8 15.8 7.5 8.0 9.2 7.6 7.7 9.8 9.3 8.2 9.1 9.0 9.3 9.8 224.9 192.3 183.9 31.6 177.8 192.2 313.7 665.2 114.4 56.5 137.9 95.5 58.3 124.4 427.7 167.3 41.7 655.2 319.6 228.7 70.5 401.2 24.3 178.8 300.3 223.7 186.1 95.3 29.2 390.4 807.8 350.7 261.0 328.5 261.6 255.1 233.1 342.2 426.0 70.7 38.3 523.1 231.9 157.3 292.2 26.7 253.5 246.5 243.7 36.5 258.0 128.3 279.1 29.7 38.8 279.9 196.8 276.8 341.1 286.5 234.3 129.1 245.6 61.9 124.9 138.4 389.7 186.4 147.6 138.9 148.5 1048.8 237.8 390.8 335.4 291.7 PDIK1L CLIK1L ENSG00000175087 "PDLIM1 interacting kinase 1 like" Q8N165 1 26111165-26125555 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064157 Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA064157: " "unprognostic (1.09e-1)" "unprognostic (1.81e-3)" "unprognostic (2.99e-3)" "unprognostic (2.52e-2)" "unprognostic (2.54e-1)" "unprognostic (1.34e-3)" "unprognostic (3.93e-2)" "unprognostic (1.72e-3)" "unprognostic (7.29e-3)" "unprognostic (1.08e-1)" "unprognostic (2.42e-2)" "unprognostic (3.59e-1)" "unprognostic (1.34e-2)" "unprognostic (4.24e-3)" "unprognostic (2.94e-1)" "unprognostic (4.47e-1)" "unprognostic (1.78e-2)" 3.2 3.4 4.4 4.5 4.0 16.6 8.2 6.6 5.1 5.9 2.7 6.9 7.1 4.4 4.6 4.9 5.4 3.9 3.3 4.1 5.2 6.0 8.1 4.6 6.5 3.9 4.0 6.5 7.8 7.0 2.6 3.4 4.8 4.7 7.3 8.3 6.3 5.0 4.8 5.5 5.6 3.6 3.8 4.6 7.3 5.0 4.9 8.6 15.4 5.2 6.3 4.6 3.2 4.9 7.9 2.9 7.5 9.8 2.7 3.8 2.6 2.3 2.7 5.2 3.3 2.0 11.2 17.8 6.3 2.6 4.0 5.6 11.2 4.0 4.4 6.1 7.7 15.3 4.3 2.2 4.7 15.6 9.0 2.2 5.9 4.6 8.5 3.5 4.8 15.3 18.0 16.8 1.8 4.8 23.5 7.4 3.5 9.5 4.7 12.7 7.3 19.2 3.7 6.1 13.3 10.8 8.2 10.0 10.5 2.0 5.4 5.4 4.4 5.5 5.2 7.0 6.9 23.8 26.5 12.0 5.9 19.2 5.0 10.5 3.8 3.3 4.8 3.6 4.5 4.9 6.6 5.3 7.3 4.2 7.0 5.6 0.3 4.4 5.1 2.8 7.9 4.0 4.4 4.0 6.6 5.1 4.1 5.2 3.9 4.0 4.8 3.8 4.9 4.9 6.4 9.6 4.2 5.9 6.2 3.2 1.7 3.5 7.4 18.6 8.6 3.9 2.3 7.2 7.0 1.8 0.0 3.9 2.7 6.5 0.0 3.7 1.3 3.2 5.7 5.0 13.1 6.3 13.7 4.0 0.7 3.8 7.1 4.9 7.0 6.3 5.0 11.1 4.1 23.5 15.4 8.0 4.1 6.3 5.9 0.5 2.5 4.6 3.6 5.6 3.1 11.0 0.0 10.1 12.1 2.9 3.3 3.0 14.0 3.5 4.5 7.5 8.4 11.7 0.0 2.9 3.6 14.0 11.7 14.5 7.4 1.6 5.4 3.0 8.7 3.0 PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 216.2;tongue: 285.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 123.0;Proximal tubular cells: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Mitochondria" "HPA008287: AB_1079589" "unprognostic (2.74e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.16e-1)" "unprognostic (2.43e-3)" "unprognostic (1.22e-1)" "unprognostic (9.63e-3)" "unprognostic (9.80e-3)" "unprognostic (8.39e-3)" "unprognostic (3.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.17e-2)" "unprognostic (2.21e-1)" "prognostic favorable (9.59e-5)" "unprognostic (3.81e-1)" "unprognostic (2.54e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" 40.8 63.8 49.9 8.7 51.2 5.0 26.4 65.7 58.2 30.5 37.1 42.7 28.1 29.4 124.4 21.8 24.3 18.0 116.6 50.6 41.8 62.7 50.8 15.3 10.1 40.8 44.0 48.2 44.3 40.7 17.0 14.7 41.8 23.5 21.5 14.7 25.7 27.4 216.2 26.0 32.5 25.7 40.8 18.4 33.7 13.7 44.6 12.6 27.3 285.0 9.2 30.9 22.2 44.6 12.4 17.5 20.6 18.5 21.2 16.5 2.2 13.2 19.3 19.3 18.5 1.7 13.2 15.5 21.7 37.0 13.0 6.4 13.7 5.3 18.8 30.6 19.3 14.0 17.1 13.2 11.3 0.0 15.0 33.6 19.6 12.5 0.9 33.7 17.2 20.0 5.7 15.0 11.0 15.8 11.8 0.0 4.5 37.2 17.1 17.5 45.8 21.1 10.4 10.4 13.8 20.7 18.7 5.9 9.0 25.0 35.0 13.7 8.8 22.5 18.4 16.0 10.1 29.4 29.9 8.2 33.3 4.9 15.4 14.3 16.2 8.9 16.2 12.9 12.8 12.9 14.8 18.0 18.4 13.8 17.2 18.0 2.6 22.9 14.1 25.8 22.4 17.4 49.9 51.2 65.7 58.2 50.6 41.8 40.8 44.0 41.8 40.8 44.6 44.6 17.9 9.6 10.3 18.3 12.1 15.2 12.3 12.4 17.6 19.0 16.0 26.8 5.4 12.8 11.7 20.2 6.2 19.6 16.7 38.6 58.7 11.7 8.8 6.5 12.1 11.8 13.8 10.8 18.6 9.1 3.6 17.7 13.7 7.8 1.3 19.0 18.2 52.0 19.9 43.7 15.6 50.2 16.2 13.6 9.1 18.9 24.2 12.0 24.9 8.4 14.5 37.3 7.2 6.0 11.3 6.2 55.2 52.6 25.9 6.7 123.0 131.9 6.5 11.0 19.7 15.0 20.5 3.3 11.7 14.6 18.8 7.9 12.9 29.0 36.9 11.3 PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 82.4;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 74.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA029685: AB_10600219, HPA029686: AB_10602309" "prognostic unfavorable (1.34e-5)" "unprognostic (1.44e-1)" "prognostic favorable (5.74e-5)" "unprognostic (5.76e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-2)" "unprognostic (3.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "prognostic favorable (3.75e-7)" "unprognostic (2.25e-1)" "unprognostic (2.86e-1)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" 7.9 17.9 4.6 6.3 5.2 9.0 8.1 6.1 5.7 9.2 6.8 12.4 9.3 6.8 6.5 8.6 8.6 8.7 13.9 4.6 5.2 21.6 27.1 8.0 7.6 4.9 4.7 9.1 8.4 13.2 8.5 6.8 5.0 14.6 13.2 6.0 15.3 7.4 12.5 6.3 9.6 8.5 4.7 6.7 9.6 7.7 5.3 8.1 13.3 13.7 7.1 7.6 6.1 6.1 7.6 10.0 8.3 13.2 14.2 18.0 19.2 13.1 16.5 12.4 11.8 10.0 10.8 14.4 11.7 14.7 13.1 10.2 20.3 16.5 16.7 9.1 9.8 14.4 11.4 16.9 15.0 18.5 11.1 13.5 19.1 19.5 15.3 10.8 13.1 16.5 20.7 19.0 12.2 9.3 5.4 19.7 5.3 17.3 12.7 9.7 7.4 11.7 15.2 10.2 8.2 7.1 9.0 15.4 19.7 9.0 12.7 22.3 8.3 8.8 5.2 12.4 11.4 5.3 6.8 11.3 16.3 27.4 16.3 3.2 5.1 2.8 3.7 5.9 5.9 4.7 3.8 4.7 7.0 5.5 5.0 4.8 0.6 3.6 9.9 3.3 5.5 3.4 4.6 5.2 6.1 5.7 4.6 5.2 4.9 4.7 5.0 4.7 5.3 6.1 11.4 16.0 19.1 64.9 12.3 4.2 13.8 11.7 13.6 8.2 9.7 8.3 17.4 12.8 13.9 14.7 2.1 26.9 8.3 15.1 35.2 12.7 37.3 16.3 9.3 8.4 10.3 8.0 53.5 14.5 17.3 9.5 8.2 10.9 14.0 11.9 7.5 32.6 11.8 6.7 67.3 15.3 14.2 9.8 5.1 12.7 5.3 10.2 7.2 82.4 8.5 11.8 6.2 72.9 74.5 13.7 14.4 9.4 13.0 12.2 14.2 40.8 21.0 11.5 26.3 8.7 7.9 21.7 11.5 14.3 5.8 11.9 9.8 13.4 17.0 12.5 PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2083.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 3705.6;Hepatocytes: 2242.4;Proximal enterocytes: 2177.7;Proximal tubular cells: 4542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904" Enhanced Approved "Plasma membrane,Cytosol" NA NA 51000000 "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB009906: AB_2163173, CAB013493: AB_2533305, HPA008819: AB_1855173, HPA063904: AB_2732708" "unprognostic (4.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.28e-2)" "unprognostic (3.39e-3)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (7.35e-3)" "unprognostic (5.67e-2)" "unprognostic (3.55e-2)" "prognostic favorable (1.52e-4)" "unprognostic (1.63e-1)" "prognostic favorable (2.15e-13)" "unprognostic (2.17e-1)" "unprognostic (7.72e-2)" "unprognostic (7.96e-2)" "unprognostic (8.80e-2)" 217.9 1754.1 941.2 84.0 966.0 121.8 235.5 987.9 1049.0 258.0 958.4 208.9 601.4 186.6 383.7 219.5 218.4 154.8 463.8 932.6 951.5 1046.1 2083.1 176.4 122.7 959.0 965.9 335.9 357.5 1162.7 292.3 128.8 982.6 261.6 191.2 336.1 344.5 233.2 580.3 190.3 510.6 167.6 1006.6 121.2 201.7 152.2 1025.0 138.1 739.7 546.8 160.2 200.8 179.0 1081.7 289.2 241.6 340.0 348.8 493.5 250.2 500.0 214.5 262.3 347.7 177.1 151.6 96.4 439.6 221.3 336.2 139.9 194.4 495.0 202.8 257.7 115.1 454.2 220.0 274.7 1021.7 289.2 403.6 94.5 240.8 334.7 203.9 140.0 396.1 162.7 240.9 375.8 169.2 356.4 346.3 226.8 813.7 319.7 243.1 273.9 446.1 235.6 829.7 428.7 277.2 397.5 306.9 439.9 306.2 446.0 200.4 443.6 293.0 168.9 253.7 147.0 254.0 237.3 161.6 315.1 234.1 301.1 303.2 280.9 5.0 67.5 20.0 155.2 76.4 247.0 271.7 258.9 193.1 205.1 210.0 244.6 201.2 8.0 138.1 68.6 231.6 259.7 258.4 941.2 966.0 987.9 1049.0 932.6 951.5 959.0 965.9 982.6 1006.6 1025.0 1081.7 193.7 403.8 433.3 101.5 230.9 318.1 449.3 367.6 288.5 539.4 538.4 590.7 697.3 713.4 243.2 783.5 95.9 999.6 144.6 207.1 3705.6 507.9 44.3 499.3 319.0 186.5 320.6 218.1 93.7 244.6 862.3 347.9 169.2 369.8 371.8 419.7 213.8 2242.4 591.6 721.8 99.6 378.8 335.7 201.4 239.0 84.4 543.1 195.3 743.5 53.4 296.8 1792.2 101.0 39.2 199.8 184.2 313.3 731.6 279.3 517.4 2177.7 4542.6 291.6 411.6 368.1 337.5 347.8 330.6 145.7 367.7 325.2 615.5 216.7 921.6 631.3 399.5 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 PEX12 ENSG00000108733 "Peroxisomal biogenesis factor 12" O00623 17 35574795-35578863 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 17.2;Spermatocytes: 21.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069386 Enhanced NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA069386: AB_2686135" "unprognostic (1.45e-1)" "unprognostic (6.06e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-1)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (1.98e-1)" "unprognostic (9.04e-2)" "unprognostic (2.59e-1)" "unprognostic (1.69e-1)" "unprognostic (5.55e-2)" "unprognostic (2.64e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" 3.9 6.8 6.7 3.6 7.2 1.5 5.5 7.9 9.1 5.3 6.7 3.4 3.6 4.3 10.7 3.4 5.6 3.2 9.1 6.8 7.1 8.2 9.0 3.4 4.8 6.8 6.9 8.2 4.0 7.8 4.7 4.7 6.8 5.7 2.9 4.6 5.5 6.9 10.3 4.2 3.5 3.5 7.3 3.9 3.9 6.8 7.0 3.2 7.7 10.8 4.5 3.7 2.7 8.4 2.8 3.7 5.4 4.4 11.0 9.9 3.9 7.3 8.3 6.0 6.3 3.2 3.0 6.4 11.6 4.1 4.9 7.3 6.6 4.8 5.2 2.3 8.7 4.7 3.8 5.9 12.8 6.7 1.2 9.2 9.2 3.7 10.9 7.7 4.6 5.2 7.5 6.6 7.2 2.9 7.9 3.8 2.2 6.3 5.8 3.8 9.3 6.4 7.1 4.2 4.0 4.0 4.6 3.0 9.6 6.5 7.4 3.7 3.7 5.6 3.5 6.3 4.9 13.3 9.9 7.5 6.0 5.1 5.2 2.2 1.5 3.0 1.8 1.1 3.2 2.3 3.0 1.8 1.7 2.6 4.1 3.5 1.0 2.0 1.2 1.7 2.4 1.4 6.7 7.2 7.9 9.1 6.8 7.1 6.8 6.9 6.8 7.3 7.0 8.4 2.7 3.2 0.5 6.5 3.3 0.6 1.9 1.3 1.8 2.1 2.4 2.2 6.3 0.0 2.7 3.7 0.0 6.7 1.4 1.3 3.9 3.5 17.2 1.9 2.3 3.9 1.2 0.8 1.3 1.1 4.1 2.6 2.6 1.5 2.5 2.0 3.3 5.4 2.9 1.7 1.9 1.7 2.0 2.6 0.6 3.0 3.1 1.5 1.8 1.0 0.9 8.3 1.0 4.5 2.8 2.2 1.0 1.5 0.5 2.4 2.7 3.3 1.8 2.2 0.0 2.6 3.7 21.0 10.2 1.4 1.3 5.2 2.8 3.0 2.2 1.3 PEX19 "D1S2223E, HK33, PMP1, PMPI, PXF, PXMP1" ENSG00000162735 "Peroxisomal biogenesis factor 19" P40855 1 160276807-160286348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044837, HPA051966" Supported Supported Peroxisomes NA NA 7900 "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Peroxisomes "HPA044837: AB_10962496, HPA051966: AB_2681677" "unprognostic (1.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.42e-1)" "unprognostic (4.80e-3)" "unprognostic (3.89e-2)" "unprognostic (3.88e-2)" "unprognostic (3.79e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.53e-2)" "unprognostic (8.06e-2)" "unprognostic (1.00e-1)" "prognostic favorable (2.92e-5)" "unprognostic (3.46e-2)" "unprognostic (2.25e-1)" "unprognostic (2.19e-2)" "unprognostic (1.24e-2)" 79.3 25.7 21.1 14.5 22.5 12.3 36.5 22.2 23.5 20.3 15.6 22.6 19.4 18.2 25.0 24.9 22.9 19.6 39.4 21.5 22.7 33.1 109.1 21.6 16.6 22.3 23.5 23.6 17.2 40.4 15.0 21.9 23.5 28.0 23.2 30.9 21.3 26.6 66.2 18.2 18.8 16.7 22.1 16.7 20.0 16.8 22.7 21.0 34.3 84.8 20.5 23.9 15.2 24.5 31.2 18.9 69.8 22.4 59.8 57.8 53.0 25.3 51.3 44.6 35.3 35.1 37.2 37.8 40.9 37.3 26.3 29.7 34.2 44.0 35.3 32.3 17.3 26.6 26.5 36.3 46.9 48.6 32.6 84.7 51.0 60.0 38.6 35.8 32.2 51.4 40.8 27.9 50.0 17.8 37.0 15.8 50.3 38.6 48.2 45.7 34.4 45.5 45.8 61.8 23.2 38.3 98.3 49.5 37.4 71.3 48.1 48.2 24.8 26.5 31.1 29.9 30.1 42.5 57.9 68.6 43.1 20.9 38.9 9.1 5.5 5.0 5.8 8.9 4.2 5.0 2.8 3.5 5.5 1.9 4.0 3.7 2.2 4.7 6.6 3.4 4.2 2.3 21.1 22.5 22.2 23.5 21.5 22.7 22.3 23.5 23.5 22.1 22.7 24.5 16.4 9.6 20.6 9.1 12.7 9.9 21.0 15.4 13.1 18.8 18.9 16.4 45.6 20.0 11.3 16.5 10.4 30.0 6.9 25.4 49.0 22.6 6.6 12.0 13.7 13.6 11.4 15.6 8.6 14.8 51.2 18.4 13.3 12.0 16.5 15.6 20.0 60.1 30.1 25.2 9.0 11.5 0.0 15.7 7.0 3.1 21.8 15.0 21.4 6.5 24.9 39.0 12.3 6.0 11.5 20.2 17.2 29.3 9.5 18.5 29.8 40.7 11.8 12.7 32.9 14.6 16.2 17.8 25.3 15.0 9.9 38.7 12.5 18.2 15.7 25.2 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA049202: AB_2680674" "unprognostic (1.36e-2)" "unprognostic (2.07e-2)" "prognostic favorable (1.61e-4)" "unprognostic (4.01e-3)" "unprognostic (2.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (6.88e-2)" "prognostic favorable (1.85e-10)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (2.65e-1)" 5.2 14.8 4.6 2.0 4.8 3.8 11.9 6.0 5.2 6.8 5.1 7.9 5.3 4.2 17.2 7.3 8.7 4.5 11.7 4.2 4.2 15.6 9.1 4.9 3.2 4.3 4.4 5.0 26.9 17.1 6.0 4.1 4.5 10.4 8.4 6.9 10.6 6.4 10.7 11.2 4.7 3.3 4.4 3.3 15.6 10.0 4.7 3.7 11.0 9.8 3.3 5.4 6.7 5.5 4.4 4.3 4.4 6.2 6.6 9.8 2.4 6.1 8.9 7.5 7.4 4.9 6.0 1.5 11.3 8.3 8.5 5.3 3.3 13.8 9.8 5.7 7.5 6.4 4.3 0.9 13.9 8.1 5.3 9.6 13.1 5.4 7.9 8.7 5.4 12.0 13.0 5.2 10.6 13.4 3.5 7.9 5.0 13.9 8.3 4.8 3.4 5.7 17.4 6.4 8.3 10.6 6.5 9.0 8.4 4.9 5.8 7.7 2.5 4.8 1.7 7.3 5.3 6.9 5.1 0.0 4.2 6.4 4.9 2.9 1.3 2.2 0.7 1.0 0.7 1.5 1.3 1.6 2.3 1.0 2.4 1.5 0.9 1.6 1.9 1.8 2.3 0.9 4.6 4.8 6.0 5.2 4.2 4.2 4.3 4.4 4.5 4.4 4.7 5.5 4.9 3.2 9.4 10.7 6.3 12.1 14.9 16.5 9.1 9.1 19.5 13.8 18.7 11.5 14.7 11.0 8.4 19.6 2.3 11.6 60.7 16.5 12.5 18.7 6.4 5.6 10.3 15.8 12.4 22.7 21.0 6.8 10.2 11.1 14.0 7.9 6.1 7.0 12.4 0.0 14.7 21.8 30.5 5.7 6.2 10.2 9.0 6.4 14.2 5.6 11.9 20.8 4.1 17.6 19.9 16.7 13.2 9.8 3.7 16.0 15.0 38.3 16.1 9.9 6.6 5.7 8.2 30.6 16.7 15.4 18.2 17.1 6.6 24.3 17.2 17.4 PFN2 ENSG00000070087 "Profilin 2" P35080 3 149964904-150050788 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 461.8;Ionocytes: 231.9;Muller glia cells: 289.3;Proximal tubular cells: 198.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035611, CAB037073" Enhanced NA NA 19000 "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" "CAB037073: AB_1079600, HPA035611: AB_10672870" "unprognostic (1.27e-1)" "unprognostic (9.08e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (2.93e-4)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.42e-4)" "prognostic unfavorable (2.19e-7)" "unprognostic (4.11e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-2)" "unprognostic (2.96e-3)" "unprognostic (4.86e-3)" "unprognostic (6.82e-2)" "unprognostic (1.25e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.99e-1)" 27.3 39.1 188.0 19.8 205.1 3.1 35.9 147.7 261.5 42.4 165.3 44.3 25.2 60.9 151.8 25.0 97.1 35.8 45.7 268.1 182.4 116.0 25.0 20.2 7.2 162.1 154.4 60.5 37.8 79.3 61.7 21.4 164.3 66.2 27.4 154.9 49.0 64.7 255.3 14.1 34.4 58.8 165.3 16.3 38.4 27.4 166.3 28.4 99.5 89.9 10.2 52.1 32.5 192.3 556.7 189.8 446.3 184.0 97.5 330.3 119.1 174.0 262.9 268.3 310.1 71.2 435.7 0.1 357.8 383.1 457.2 5.7 187.0 247.5 386.7 17.8 111.3 6.5 94.7 206.0 130.1 31.3 8.8 209.1 205.4 263.9 341.5 285.9 159.3 87.9 1.6 21.3 282.9 206.0 27.3 1.5 195.0 3.7 248.1 31.1 321.7 2.6 200.8 278.6 241.6 248.8 86.4 41.1 239.6 306.6 65.3 4.5 116.1 127.2 177.3 214.1 228.4 28.5 2.3 14.7 275.3 1.8 159.2 1.7 0.2 0.4 2.2 0.1 4.7 2.0 4.8 4.1 0.1 1.0 7.3 4.4 1.2 1.4 0.0 0.2 1.4 2.1 188.0 205.1 147.7 261.5 268.1 182.4 162.1 154.4 164.3 165.3 166.3 192.3 16.2 6.4 6.9 26.4 4.5 9.8 52.4 106.0 100.2 52.1 54.3 37.0 48.3 32.9 47.3 136.1 18.8 11.9 1.9 12.8 461.8 42.1 57.6 75.5 28.3 22.6 121.2 0.0 65.0 27.3 11.5 54.7 7.7 10.6 8.2 39.5 25.4 12.3 3.2 26.9 33.8 27.9 231.9 1.2 9.3 27.2 74.0 2.9 35.6 15.9 4.8 289.3 1.0 21.6 30.3 14.9 19.4 96.7 3.4 57.9 103.2 198.2 116.4 42.2 13.1 52.7 71.8 28.5 19.2 51.5 7.5 10.3 5.0 55.8 30.5 37.7 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PHB PHB1 ENSG00000167085 Prohibitin P35232 17 49404052-49414901 "Plasma proteins, Predicted intracellular proteins" "DNA synthesis, Host-virus interaction" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 473.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 749.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003280 Supported Supported Mitochondria "Intracellular and membrane" NA NA 360000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA003280: AB_1855732" "unprognostic (2.31e-2)" "unprognostic (5.70e-2)" "unprognostic (1.19e-2)" "unprognostic (7.88e-3)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.58e-4)" "prognostic unfavorable (9.91e-4)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.10e-2)" "unprognostic (1.77e-1)" "unprognostic (2.71e-2)" "unprognostic (3.09e-3)" 81.6 88.4 39.2 23.3 42.2 19.8 77.4 44.2 49.8 55.3 54.0 104.5 52.6 68.0 34.1 88.6 55.7 26.9 147.0 40.6 44.4 143.4 120.4 59.0 27.0 43.9 42.5 59.7 62.5 70.1 51.1 33.1 44.1 67.2 60.0 12.1 135.9 44.7 138.1 67.5 68.0 35.7 40.9 61.1 79.7 33.5 41.9 26.2 61.5 98.5 26.8 75.2 59.4 46.0 86.0 339.1 46.4 96.9 81.9 48.3 111.8 69.8 72.3 175.1 122.4 749.5 80.2 119.2 88.1 60.0 67.3 63.4 151.7 135.3 128.4 72.9 327.1 77.7 122.8 361.8 53.0 109.6 58.1 54.9 125.9 130.9 41.6 45.7 87.6 68.6 112.7 27.6 77.5 224.0 106.0 118.5 99.9 135.9 311.1 74.9 144.0 103.8 144.0 116.1 122.1 75.9 35.4 59.1 113.7 71.7 112.2 33.4 58.9 96.3 124.7 78.4 98.4 35.3 65.7 59.1 58.0 125.6 110.7 11.7 45.9 13.4 61.6 53.4 80.5 61.2 56.6 56.3 62.3 46.7 59.4 59.7 8.9 69.0 59.5 155.1 61.4 79.8 39.2 42.2 44.2 49.8 40.6 44.4 43.9 42.5 44.1 40.9 41.9 46.0 88.5 48.1 46.8 8.8 78.3 117.5 147.5 182.6 70.0 44.8 135.7 180.0 8.4 100.1 101.9 84.6 37.5 230.2 144.4 220.8 406.9 233.1 14.0 93.4 85.5 92.6 131.9 77.2 7.8 158.6 278.7 87.8 74.9 131.0 73.0 124.6 61.4 101.8 228.1 21.9 10.0 281.7 223.8 51.9 87.9 24.7 89.5 70.9 158.3 1.9 120.3 83.1 88.6 11.1 15.3 162.8 139.8 115.1 93.0 242.8 151.4 473.6 68.0 42.1 52.6 72.8 306.5 18.0 47.3 107.6 124.0 152.4 75.9 159.9 337.2 161.9 PHKB ENSG00000102893 "Phosphorylase kinase regulatory subunit beta" Q93100 16 47461123-47701523 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" Calmodulin-binding "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 159.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073380 Approved "Golgi apparatus" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA073380: AB_2686598" "unprognostic (2.87e-3)" "unprognostic (2.41e-1)" "prognostic favorable (3.69e-4)" "unprognostic (3.98e-2)" "unprognostic (3.98e-2)" "unprognostic (1.28e-2)" "unprognostic (6.73e-2)" "unprognostic (2.99e-2)" "unprognostic (2.35e-3)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "unprognostic (3.01e-2)" "prognostic favorable (3.89e-9)" "unprognostic (3.56e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (3.24e-4)" "unprognostic (2.53e-2)" 29.7 42.4 15.8 21.9 16.2 28.2 36.1 18.3 19.5 33.8 34.1 39.0 37.8 26.8 32.8 34.5 25.6 30.6 32.7 14.3 21.3 47.2 30.1 30.0 26.2 15.8 16.0 24.2 26.6 56.7 21.6 37.1 18.6 36.2 41.5 18.9 46.1 32.2 159.0 18.9 38.0 32.1 13.8 29.0 40.4 30.6 18.9 31.0 54.1 80.7 29.0 26.5 21.2 16.6 36.7 53.3 60.3 39.1 41.2 38.8 74.9 42.8 41.2 30.1 15.0 29.4 62.2 44.5 63.5 62.7 23.7 50.6 57.0 66.9 42.3 13.8 29.8 42.1 45.4 98.3 37.0 46.2 47.7 35.1 33.4 20.3 38.2 65.4 59.8 53.5 58.8 27.4 43.7 26.3 45.2 44.1 25.5 61.1 39.8 75.7 73.3 74.3 59.2 31.1 31.5 35.8 70.9 92.4 12.0 66.1 36.0 37.7 66.5 54.4 25.4 28.0 22.9 31.1 24.6 57.2 34.5 30.2 22.7 11.1 21.0 18.4 11.8 18.9 15.3 30.6 12.2 9.7 20.6 34.7 11.8 11.7 10.4 18.5 23.7 13.9 15.8 12.6 15.8 16.2 18.3 19.5 14.3 21.3 15.8 16.0 18.6 13.8 18.9 16.6 49.3 19.2 38.0 66.9 46.8 8.9 17.5 28.8 18.8 34.9 28.7 23.4 61.2 32.9 39.9 42.3 100.1 48.5 29.3 43.1 23.5 19.6 64.7 33.5 31.1 42.9 30.5 40.1 109.8 15.6 26.3 28.8 47.9 38.3 18.3 52.6 39.3 30.9 28.4 23.5 149.0 37.8 20.3 58.7 17.0 89.8 25.4 45.1 8.8 104.0 72.2 25.8 32.0 133.2 118.4 27.2 26.4 35.7 28.1 30.2 48.9 35.9 26.7 71.8 26.3 33.3 30.6 53.9 19.5 47.2 7.2 33.8 24.7 74.9 38.6 26.7 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715541-62980433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 107.2" "Group enriched" "Detected in many" 10 "Astrocytes: 423.7;Oligodendrocyte precursor cells: 538.3;Oligodendrocytes: 1663.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 4.0;T-reg: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 4.0;T-cells: 1.3" "Cell line enhanced" "Detected in all" "REH: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Approved "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.5 14.6 46.4 1.9 74.3 7.3 6.4 49.5 59.8 4.4 17.1 5.2 5.4 4.6 1.9 7.6 3.4 4.1 3.4 45.6 46.4 3.2 16.6 3.4 2.7 61.8 58.4 4.4 7.0 5.7 7.5 5.5 53.8 4.0 5.6 16.1 10.8 3.5 4.2 12.5 4.9 3.3 47.0 1.8 4.9 10.8 58.7 4.4 4.6 3.7 3.6 5.5 4.8 107.2 13.7 5.0 20.2 6.8 3.4 2.9 15.8 4.0 3.6 7.8 8.0 11.1 8.0 9.1 2.4 6.1 3.1 16.3 10.5 6.4 10.0 28.4 8.8 3.1 5.4 20.6 4.8 4.7 1.5 3.0 4.1 8.4 7.6 6.4 5.6 4.9 8.0 17.9 7.6 3.0 3.5 4.1 8.2 2.7 4.9 32.7 11.5 11.1 4.5 17.5 9.3 3.7 4.4 9.9 8.2 11.8 4.4 13.3 7.2 6.4 3.0 3.9 9.4 2.0 1.1 10.6 3.8 5.4 5.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 4.0 0.3 0.1 0.2 1.3 0.1 46.4 74.3 49.5 59.8 45.6 46.4 61.8 58.4 53.8 47.0 58.7 107.2 10.1 3.2 1.5 423.7 1.9 16.8 5.0 2.9 8.0 21.2 12.1 11.3 4.1 11.5 6.3 0.0 29.2 12.9 3.3 8.4 1.9 3.8 33.5 13.7 6.0 8.1 12.1 3.8 80.1 4.1 5.8 7.0 10.2 26.6 2.5 9.6 5.3 21.5 2.4 26.9 64.7 8.5 2.0 2.5 9.8 36.4 5.9 5.8 24.9 79.6 2.6 83.6 2.1 538.3 1663.2 4.5 8.0 3.8 1.0 7.5 7.4 1.9 10.0 17.4 0.0 13.5 5.3 8.0 15.4 13.2 18.6 26.1 2.7 8.3 11.1 11.0 PHYH "PAHX, PHYH1, RD" ENSG00000107537 "Phytanoyl-CoA 2-hydroxylase" O14832 10 13277796-13302412 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 667.8;skeletal muscle: 483.6;tongue: 412.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 258.6;Proximal tubular cells: 414.6" "Cancer enhanced" "Detected in all" "liver cancer: 78.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007598, HPA011796" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA007598: AB_1855334, HPA011796: AB_1855335" "unprognostic (5.78e-2)" "unprognostic (3.83e-1)" "unprognostic (6.98e-2)" "unprognostic (3.62e-2)" "unprognostic (5.52e-2)" "unprognostic (1.61e-3)" "unprognostic (1.16e-1)" "unprognostic (1.95e-2)" "unprognostic (7.09e-2)" "unprognostic (6.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.24e-1)" "prognostic favorable (7.28e-12)" "unprognostic (2.07e-1)" "unprognostic (1.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.19e-1)" 57.9 66.5 22.9 9.5 23.7 8.2 32.2 23.5 28.3 28.8 31.7 46.5 58.7 22.1 16.7 22.9 16.7 28.2 126.5 21.7 24.1 191.4 667.8 17.3 7.5 21.6 24.4 36.8 48.2 56.7 20.9 19.3 22.8 22.5 37.2 28.2 33.7 25.4 483.6 17.5 55.8 23.2 22.7 12.8 44.2 15.1 26.0 5.6 56.0 412.7 5.4 27.0 14.8 23.6 17.2 35.2 15.6 22.5 110.7 69.9 12.4 17.2 23.9 19.4 19.1 9.1 30.3 0.9 12.9 29.0 47.0 7.8 20.5 20.2 11.8 41.4 10.7 14.9 9.3 36.6 54.8 2.5 26.8 50.3 28.9 21.0 8.4 22.7 18.7 16.8 8.4 32.2 45.5 16.3 9.2 12.1 14.4 49.4 12.6 15.7 24.1 5.8 40.6 21.9 5.3 16.8 64.8 1.4 32.9 12.5 64.8 44.2 6.4 29.5 10.6 36.4 11.8 36.6 26.3 3.3 38.3 18.9 11.6 16.3 18.7 8.2 8.0 14.2 17.6 11.0 9.9 10.4 15.8 5.6 12.5 12.7 0.8 4.4 11.2 14.4 10.5 12.3 22.9 23.7 23.5 28.3 21.7 24.1 21.6 24.4 22.8 22.7 26.0 23.6 53.6 12.8 19.2 8.5 14.5 11.9 27.6 19.1 6.2 47.0 22.6 24.5 258.6 77.2 19.7 35.0 22.9 137.8 20.5 72.9 144.8 40.6 33.1 18.5 29.0 29.7 31.8 15.2 7.1 19.6 34.3 41.3 41.8 26.8 30.4 28.3 25.0 145.5 55.4 21.9 5.6 57.4 46.8 21.0 22.0 45.4 25.4 25.3 17.8 4.7 10.3 69.3 7.2 2.5 2.4 16.7 46.0 37.6 15.1 11.9 141.9 414.6 19.6 41.8 19.7 30.2 37.5 12.5 1.6 7.3 13.4 83.9 25.2 103.3 46.9 18.1 PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" 6.4 4.8 2.3 5.8 2.6 9.1 9.0 2.8 2.6 5.5 3.1 7.0 7.5 6.4 11.0 5.7 7.8 6.3 2.8 2.5 3.3 10.3 9.4 6.3 8.2 2.8 2.7 4.7 5.7 10.6 3.9 4.8 2.6 7.7 7.8 7.9 4.3 6.8 1.5 6.1 5.8 5.6 2.7 6.1 7.6 6.5 2.7 6.3 13.3 1.8 8.6 7.5 3.7 3.1 10.5 12.2 5.8 4.1 6.6 13.2 7.8 9.0 19.9 10.4 17.8 5.1 10.3 10.9 10.4 12.9 15.6 18.3 3.3 9.5 8.6 10.4 6.4 10.9 13.6 6.7 11.9 30.8 8.7 12.5 11.4 7.9 10.7 13.8 13.6 9.2 12.2 6.9 15.0 9.1 3.4 12.8 3.1 7.9 4.8 4.9 5.6 24.1 18.4 12.4 2.5 6.2 8.1 12.2 17.3 5.4 11.7 22.2 9.5 13.6 4.3 3.7 18.6 8.1 15.9 8.6 12.4 34.5 10.2 13.6 7.7 3.3 6.2 9.7 7.0 6.0 6.1 6.9 7.0 3.9 4.8 5.5 14.5 5.3 11.4 5.4 6.5 5.5 2.3 2.6 2.8 2.6 2.5 3.3 2.8 2.7 2.6 2.7 2.7 3.1 3.5 9.6 9.5 17.6 27.5 4.6 9.5 14.9 4.6 3.3 5.6 4.2 3.4 1.5 14.9 0.0 12.5 12.4 11.2 4.8 1.9 7.4 26.8 4.3 3.2 4.7 6.6 8.2 18.3 10.9 12.0 6.0 6.1 6.4 8.2 4.6 6.8 4.4 8.6 1.7 17.7 4.1 4.1 7.5 6.7 5.1 1.5 8.8 3.6 12.2 8.4 2.7 11.3 17.1 14.6 6.9 4.0 1.5 3.8 3.4 6.4 9.7 7.9 9.4 6.6 4.8 4.2 5.9 3.8 5.7 4.0 6.6 12.5 4.2 4.0 7.4 PIGV FLJ20477 ENSG00000060642 "Phosphatidylinositol glycan anchor biosynthesis class V" Q9NUD9 1 26787054-26800659 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 50.8;Late spermatids: 96.0;Spermatocytes: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054181 Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Endoplasmic reticulum" "HPA054181: " "unprognostic (2.08e-1)" "unprognostic (6.53e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (1.56e-1)" "unprognostic (8.40e-2)" "unprognostic (4.44e-2)" "prognostic favorable (7.60e-7)" "unprognostic (1.71e-1)" "unprognostic (4.24e-1)" "unprognostic (8.92e-2)" "unprognostic (5.96e-3)" 6.6 13.9 4.6 3.4 5.3 3.0 7.6 5.1 4.8 9.5 4.1 8.1 6.5 8.1 13.8 9.0 10.2 6.2 4.4 4.2 4.7 10.9 24.1 6.2 4.2 6.1 5.2 7.9 10.3 13.9 10.0 6.2 5.5 8.4 8.4 3.7 10.0 8.0 4.4 11.3 7.3 6.7 5.2 6.9 8.9 30.0 5.1 6.7 10.6 4.8 6.4 8.5 8.3 5.4 10.6 4.4 4.1 4.7 7.3 10.8 5.8 6.7 14.0 7.6 7.9 2.3 25.9 6.7 7.3 7.7 8.2 20.3 4.2 8.6 8.6 11.5 2.5 5.6 5.1 5.1 10.3 7.7 10.0 11.8 43.8 9.8 12.2 12.0 5.1 9.4 10.0 12.2 14.0 3.9 3.7 3.0 9.9 20.9 3.0 3.8 6.2 15.0 11.0 1.0 7.6 3.9 9.2 4.3 8.7 9.8 14.1 6.5 8.1 10.8 6.5 6.0 1.8 3.8 2.2 2.9 10.7 10.0 8.2 33.1 14.1 11.0 14.0 13.0 21.1 8.8 9.9 14.4 12.5 8.8 10.2 12.4 14.2 21.5 18.5 4.5 9.7 10.8 4.6 5.3 5.1 4.8 4.2 4.7 6.1 5.2 5.5 5.2 5.1 5.4 5.2 3.2 6.0 7.5 6.0 4.2 11.0 27.5 6.2 3.3 10.0 7.6 1.9 4.3 12.7 7.3 8.4 27.4 10.6 5.0 7.9 7.2 50.8 6.7 4.7 4.6 3.5 13.5 2.8 4.6 14.8 8.8 6.1 6.4 0.0 6.8 6.4 16.6 9.2 8.4 3.2 6.5 12.2 5.2 3.2 96.0 7.2 4.2 7.2 2.8 8.2 11.1 7.2 0.0 5.5 4.9 4.8 9.8 6.5 7.6 12.1 10.2 16.3 2.7 0.0 5.7 4.9 80.8 15.1 7.3 4.1 14.1 8.2 12.1 9.2 8.4 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PJA1 "FLJ11830, RNF70" ENSG00000181191 "Praja ring finger ubiquitin ligase 1" Q8NG27 X 69160851-69165521 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 160.0" "Cell type enhanced" "Detected in many" "Early spermatids: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000595 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA000595: AB_1079826" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (4.03e-2)" "unprognostic (2.58e-3)" "unprognostic (5.44e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-2)" "unprognostic (3.82e-3)" "unprognostic (1.84e-2)" "unprognostic (6.10e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.44e-5)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-1)" 22.9 14.5 46.8 8.7 50.5 3.6 19.4 37.2 78.0 19.9 33.0 15.4 6.4 16.4 160.0 12.3 16.0 11.1 15.0 47.1 48.9 19.2 9.4 13.8 10.0 38.9 41.7 25.8 14.5 38.7 28.1 17.3 40.6 15.3 7.6 17.6 10.6 32.4 7.9 14.6 11.1 16.0 40.1 13.3 14.0 26.4 49.0 10.0 22.7 8.8 12.1 17.4 15.1 43.5 27.3 19.6 62.9 43.7 21.3 22.5 18.7 17.8 22.0 16.7 22.3 17.1 25.8 4.4 26.7 28.1 39.2 24.0 99.0 34.9 21.2 20.2 33.0 8.1 16.0 10.9 25.7 4.9 14.4 23.1 23.6 28.6 17.0 15.8 19.0 13.2 7.8 3.0 16.9 14.1 2.1 8.4 43.4 23.1 32.0 20.0 28.2 6.9 23.4 22.6 46.4 30.7 28.6 4.9 22.2 50.1 7.7 7.0 17.8 13.9 22.6 41.7 8.3 0.0 0.2 9.1 15.3 13.1 19.4 6.6 6.8 2.1 29.6 9.2 34.3 16.4 26.1 27.5 7.3 22.8 26.5 31.3 2.3 30.0 6.5 8.9 17.5 19.4 46.8 50.5 37.2 78.0 47.1 48.9 38.9 41.7 40.6 40.1 49.0 43.5 4.7 16.0 4.8 2.9 9.7 41.0 19.4 30.8 23.9 16.8 5.0 6.2 7.1 4.3 14.8 3.7 8.4 35.6 5.9 1.0 15.6 24.9 74.7 3.9 10.4 6.6 5.4 10.8 8.1 11.7 15.3 18.2 7.1 5.8 4.5 27.9 6.8 1.7 7.0 5.0 8.3 3.6 6.1 2.9 9.9 32.7 27.1 5.7 5.4 2.8 2.9 30.6 14.4 5.0 3.7 18.0 1.7 19.5 7.7 17.0 0.5 6.5 4.4 6.1 6.6 9.4 16.3 1.4 1.5 11.2 29.5 20.8 11.2 27.0 2.6 22.5 PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1160.4;tongue: 953.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.8;Cardiomyocytes: 367.0;Excitatory neurons: 103.3;Inhibitory neurons: 78.2;Muller glia cells: 82.8;Oligodendrocyte precursor cells: 82.9" "Cancer enhanced" "Detected in many" "glioma: 15.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.4" "Lineage enriched" "Detected in many" 9 "T-cells: 21.4" "Cell line enhanced" "Detected in many" "HDLM-2: 63.9;HUVEC TERT2: 104.0;RT4: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042791: AB_10795761" "unprognostic (3.83e-3)" "unprognostic (1.89e-1)" "unprognostic (1.55e-2)" "unprognostic (5.59e-6)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.10e-3)" "unprognostic (1.65e-3)" "unprognostic (3.25e-2)" "unprognostic (2.58e-1)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (5.41e-4)" "unprognostic (3.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.52e-3)" 2.5 9.5 44.4 5.6 49.3 2.7 4.1 41.4 49.2 2.2 11.9 3.5 1.2 3.1 3.0 21.5 5.3 8.2 185.9 49.8 44.0 4.7 0.2 8.6 7.6 25.4 34.3 5.8 1.4 108.1 8.0 1.6 36.0 20.3 2.8 33.7 6.2 5.3 1160.4 9.2 2.5 2.6 35.2 4.1 1.6 1.3 48.1 26.3 34.2 953.8 11.0 9.5 3.6 36.2 0.6 0.3 34.2 0.0 18.5 4.8 0.2 32.1 6.3 3.4 7.2 0.0 5.3 14.8 0.2 4.8 3.3 0.5 11.3 10.3 22.3 63.9 24.6 18.5 3.7 0.2 1.2 0.0 10.3 7.7 1.5 0.0 9.6 45.5 104.0 19.8 0.0 15.8 51.4 5.4 28.3 0.0 8.1 0.0 35.3 0.0 29.3 0.0 18.7 100.2 16.6 32.5 4.1 26.4 0.0 8.9 0.0 0.1 41.2 7.8 6.4 1.8 19.2 6.5 6.9 4.9 36.9 0.1 9.8 0.0 0.0 0.0 0.5 0.1 0.4 2.3 9.1 1.8 0.1 2.2 7.7 4.6 0.4 1.7 0.1 0.2 21.4 2.5 44.4 49.3 41.4 49.2 49.8 44.0 25.4 34.3 36.0 35.2 48.1 36.2 0.6 3.2 2.8 104.8 9.8 5.9 8.8 4.5 19.9 40.2 2.6 6.5 367.0 0.0 2.0 1.8 2.1 3.1 2.7 0.4 1.9 0.0 13.9 0.9 0.2 9.1 10.2 4.2 103.3 0.2 2.8 12.3 0.0 1.3 5.7 18.6 2.5 0.0 0.7 58.9 78.2 0.8 6.1 0.0 1.1 5.9 0.0 3.9 3.6 15.0 0.5 82.8 0.0 82.9 17.9 1.5 0.1 0.4 2.3 6.1 0.0 0.1 1.0 6.9 0.0 22.9 4.8 0.4 0.6 13.9 13.8 3.4 8.0 0.1 0.3 3.6 PKMYT1 "MYT1, PPP1R126" ENSG00000127564 "Protein kinase, membrane associated tyrosine/threonine 1" Q99640 16 2968024-2980479 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.6;testis: 56.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 29.0;Extravillous trophoblasts: 52.0;Plasma cells: 22.9;Spermatocytes: 114.7;Spermatogonia: 46.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "T-reg: 1.3" "Lineage enriched" "Detected in single" 6 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068860 Supported "Nucleoplasm,Nucleoli,Golgi apparatus" NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA068860: AB_2686050" "unprognostic (7.82e-2)" "unprognostic (8.70e-2)" "unprognostic (5.93e-2)" "unprognostic (2.04e-2)" "unprognostic (4.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.33e-4)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.52e-2)" "unprognostic (2.15e-1)" "unprognostic (1.61e-2)" "unprognostic (7.95e-3)" "unprognostic (0.00e+0)" "unprognostic (1.09e-3)" "unprognostic (9.13e-2)" "unprognostic (1.96e-1)" "unprognostic (5.91e-2)" 1.1 1.0 0.4 6.8 0.5 27.6 0.6 1.6 1.4 2.2 0.2 3.9 2.8 0.6 0.3 11.5 0.4 0.6 0.9 0.5 0.2 0.9 1.6 2.0 8.0 0.7 0.6 0.3 1.8 0.1 1.0 3.1 0.8 1.0 1.3 17.4 1.9 0.1 2.4 4.4 4.0 1.0 0.5 5.6 3.3 56.9 0.7 9.6 0.5 0.0 4.5 0.7 3.3 0.8 84.2 57.0 22.0 31.2 0.3 0.9 64.0 65.5 15.1 40.0 38.4 45.0 49.3 54.2 29.2 7.9 24.2 106.7 15.7 20.7 7.2 71.7 56.7 27.9 52.7 40.0 0.0 31.2 73.6 0.7 1.8 24.0 6.5 5.0 8.4 57.6 80.6 87.0 13.5 127.5 83.6 88.0 37.9 39.3 34.4 93.7 51.2 100.7 7.8 17.7 42.6 46.7 31.9 77.7 23.9 12.1 44.7 56.9 7.7 53.2 69.7 77.3 68.0 67.6 54.2 94.0 19.4 40.0 61.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.3 0.3 0.4 0.5 1.6 1.4 0.5 0.2 0.7 0.6 0.8 0.5 0.7 0.8 0.0 0.0 1.1 0.0 1.9 2.5 1.3 2.1 0.6 0.4 1.5 1.3 0.6 1.5 1.6 1.8 6.2 16.0 1.3 5.0 0.0 0.8 20.0 0.6 0.8 0.8 1.8 29.0 0.4 0.6 52.0 2.5 3.1 1.9 0.0 4.5 0.0 0.4 11.8 0.0 0.2 3.6 6.1 2.1 1.8 8.6 0.3 1.9 0.0 0.0 0.7 0.2 0.0 0.0 0.3 0.6 0.3 0.4 22.9 0.7 0.3 0.1 0.2 7.1 0.0 0.1 2.6 114.7 46.1 11.2 0.6 7.4 4.2 0.5 8.6 2.0 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHB2 "EVT2, FLJ20783" ENSG00000115762 "Pleckstrin homology domain containing B2" Q96CS7 2 131104847-131353709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075014 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA075014: AB_2732275" "unprognostic (1.99e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "unprognostic (8.78e-2)" "unprognostic (5.18e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (9.33e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.72e-8)" "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.14e-2)" "unprognostic (2.65e-1)" 27.0 55.5 52.7 38.3 55.4 64.8 26.1 61.4 56.2 25.4 53.4 59.9 46.8 16.6 30.7 30.3 26.7 29.7 33.5 57.8 73.1 111.8 22.4 44.4 37.0 64.8 69.4 11.7 20.8 88.5 26.2 31.0 81.3 34.6 60.9 81.1 26.0 26.3 35.6 23.5 56.2 25.9 56.8 42.5 58.5 36.1 60.0 31.2 48.7 30.6 34.5 38.3 18.2 63.1 85.3 65.4 48.6 38.1 37.4 36.2 79.2 94.4 80.0 88.9 73.8 140.0 83.4 68.2 97.5 92.0 64.4 58.8 89.0 81.5 98.8 40.0 48.6 119.4 31.0 81.4 51.9 115.4 88.8 31.9 67.2 105.2 96.9 54.6 71.1 36.5 57.5 53.0 166.9 46.7 71.4 57.0 73.9 80.8 99.1 52.5 37.7 72.7 138.6 89.7 60.3 39.7 29.6 166.3 107.6 64.9 23.6 89.0 86.6 89.2 60.4 76.7 86.5 51.2 85.6 46.5 130.8 76.6 82.8 27.5 54.9 29.0 24.4 69.2 23.9 15.5 18.2 23.2 52.7 17.1 19.4 23.2 32.3 26.5 78.2 18.7 23.6 48.3 52.7 55.4 61.4 56.2 57.8 73.1 64.8 69.4 81.3 56.8 60.0 63.1 37.8 60.9 53.9 14.4 50.0 114.3 35.6 47.2 64.9 85.6 57.6 26.5 28.6 34.3 59.5 64.4 125.1 44.9 59.5 174.4 158.5 62.4 66.4 108.8 44.2 57.2 56.8 44.2 38.9 43.1 51.0 29.6 62.2 164.1 58.9 25.4 31.4 20.9 106.3 101.0 41.5 67.6 128.1 111.0 169.5 22.1 14.3 117.9 76.5 26.2 86.2 46.0 49.4 15.1 32.0 81.5 68.4 24.0 35.8 58.6 120.2 193.4 52.1 78.8 13.1 26.1 35.9 92.3 65.9 97.6 140.4 92.9 59.1 51.0 76.1 70.7 PLGRKT "AD025, C9orf46, FLJ14688, MDS030, Plg-RKT" ENSG00000107020 "Plasminogen receptor with a C-terminal lysine" Q9HBL7 9 5357971-5437925 "Predicted intracellular proteins" "Chemotaxis, Inflammatory response, Plasminogen activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 191.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 244.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 247.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008214, HPA011144" Supported Uncertain Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA008214: AB_1078363, HPA011144: AB_1078364" "prognostic favorable (5.56e-4)" "unprognostic (5.31e-2)" "unprognostic (2.96e-2)" "unprognostic (9.67e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (1.72e-1)" "unprognostic (1.89e-2)" "unprognostic (3.85e-2)" "unprognostic (5.45e-3)" "unprognostic (2.19e-2)" "unprognostic (1.84e-1)" "prognostic favorable (5.09e-5)" "unprognostic (1.45e-2)" "unprognostic (1.47e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-1)" 18.9 17.9 9.6 20.2 10.5 13.6 25.4 10.3 13.8 18.1 15.3 41.2 44.1 12.3 27.7 20.3 19.8 15.6 33.6 9.5 10.1 33.4 21.6 14.6 23.9 10.3 9.8 10.0 12.5 19.9 10.4 15.0 10.7 17.4 46.8 15.8 16.7 13.5 58.6 16.4 36.3 17.3 10.6 14.5 20.0 4.8 9.8 35.3 24.8 37.1 22.7 17.6 12.8 11.1 54.8 15.4 31.8 23.0 20.0 27.7 0.1 26.2 29.0 22.1 25.5 0.2 24.2 12.4 13.7 19.8 32.7 12.6 21.9 72.0 46.1 247.5 14.0 97.6 12.5 17.4 43.3 29.8 22.4 30.6 25.8 20.6 42.0 18.9 32.2 41.0 5.5 86.2 54.3 12.0 32.1 33.6 20.6 44.5 8.9 20.1 15.6 39.6 50.6 11.4 25.1 32.7 26.0 40.6 50.6 22.5 32.8 41.4 23.1 28.0 34.8 24.7 51.7 16.4 25.3 25.6 48.6 18.6 16.1 244.3 18.8 38.3 43.0 25.5 54.0 48.9 53.7 56.7 27.6 42.9 51.1 51.2 22.8 52.7 17.9 44.3 74.9 44.0 9.6 10.5 10.3 13.8 9.5 10.1 10.3 9.8 10.7 10.6 9.8 11.1 27.8 12.8 25.5 25.5 22.0 26.4 23.4 144.2 27.3 11.8 56.9 58.7 58.7 22.8 49.7 22.0 0.0 88.6 23.1 139.2 109.5 82.5 0.8 39.6 28.1 21.2 26.5 25.2 18.8 51.1 108.7 25.3 20.9 22.0 90.7 14.6 15.0 27.5 82.8 10.1 26.7 124.2 83.4 21.7 35.6 1.9 16.4 33.0 33.8 21.5 84.3 24.4 24.7 20.1 40.5 82.7 157.2 19.9 23.0 27.3 191.3 76.8 52.6 15.1 0.0 26.0 33.2 21.2 13.7 41.1 30.3 65.8 33.0 23.1 106.1 24.0 PLN "CMD1P, PLB" ENSG00000198523 Phospholamban P26678 6 118548296-118561716 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "heart muscle: 1563.4;skeletal muscle: 507.3" "Cell type enriched" "Detected in some" 8 "Cardiomyocytes: 2452.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB005597, HPA026900" Enhanced NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB005597: AB_2252716, HPA026900: AB_1855314" "unprognostic (2.49e-1)" "unprognostic (5.67e-2)" "unprognostic (1.96e-3)" "unprognostic (4.81e-2)" "unprognostic (1.20e-1)" "unprognostic (5.54e-2)" "unprognostic (2.35e-3)" "unprognostic (4.66e-2)" "unprognostic (3.97e-1)" "unprognostic (8.98e-2)" "unprognostic (8.98e-2)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.11e-4)" "unprognostic (2.98e-3)" "unprognostic (1.80e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (5.59e-4)" 40.1 12.3 1.5 12.3 3.0 0.6 15.9 2.9 4.0 31.7 2.0 148.7 13.6 121.7 21.8 43.9 81.9 92.2 1563.4 1.6 1.6 15.0 1.2 15.4 2.7 1.8 2.0 20.4 3.2 1.3 1.5 0.3 1.8 35.1 24.4 0.2 5.3 37.0 507.3 8.3 41.6 128.4 1.5 3.0 34.1 4.3 2.2 1.0 12.7 230.2 0.9 44.1 22.9 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 3.0 2.9 4.0 1.6 1.6 1.8 2.0 1.8 1.5 2.2 2.0 4.5 0.0 0.0 0.3 0.2 4.2 0.2 0.0 1.2 1.8 0.4 0.6 2452.8 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 108.2 0.2 0.7 21.4 0.0 0.0 1.0 0.0 0.0 49.1 0.5 0.1 0.0 0.1 0.7 0.1 0.1 0.0 0.9 0.0 0.0 0.0 4.7 25.0 0.9 0.4 3.6 1.0 0.0 0.0 0.0 2.0 1.1 0.1 0.0 11.7 0.0 0.7 0.0 0.0 0.0 0.3 276.1 16.7 248.0 9.2 0.8 0.3 1.6 0.0 0.8 0.0 0.0 0.4 PLOD2 LH2 ENSG00000152952 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2" O00469 3 146069440-146163653 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Basal respiratory cells: 115.1;Distal enterocytes: 143.7;Extravillous trophoblasts: 130.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBF TERT88: 636.0;hTERT-RPE1: 723.8;U-87 MG: 566.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025898, HPA069126" Approved Uncertain Nucleoli,Cytosol "Intracellular and membrane" NA NA 21000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "CAB025898: , HPA069126: " "unprognostic (8.68e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (2.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (1.29e-3)" "prognostic unfavorable (7.64e-10)" "prognostic unfavorable (1.42e-4)" "unprognostic (2.97e-2)" "unprognostic (3.36e-2)" "unprognostic (6.27e-3)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.99e-11)" "prognostic unfavorable (2.83e-4)" "unprognostic (6.07e-2)" "unprognostic (4.06e-2)" "unprognostic (4.41e-3)" 63.1 20.1 13.4 35.6 14.5 1.1 18.6 15.1 17.2 10.2 19.4 36.2 42.2 23.5 13.4 18.2 11.4 41.5 22.1 13.3 15.1 26.1 57.3 12.9 3.8 23.1 18.1 20.5 18.7 16.5 7.9 80.6 16.3 13.2 29.9 56.6 9.5 16.2 3.0 3.9 35.0 46.8 17.8 5.4 20.1 8.5 20.6 10.5 90.0 3.9 5.5 25.7 10.0 17.6 134.5 94.3 29.0 9.5 102.5 109.6 73.2 465.5 141.6 247.7 463.0 7.2 13.4 0.0 88.8 79.5 113.1 27.8 34.0 400.5 636.0 0.6 53.5 33.3 84.3 66.9 262.5 0.1 0.6 192.9 56.5 215.2 104.1 723.8 347.7 0.1 45.1 1.8 441.6 48.8 0.3 0.6 18.5 0.3 40.0 0.2 19.2 0.6 105.0 6.5 14.5 0.5 370.3 39.4 39.9 135.1 107.5 4.2 440.4 304.2 92.2 97.8 280.7 138.9 20.9 0.5 566.5 0.4 55.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 13.4 14.5 15.1 17.2 13.3 15.1 23.1 18.1 16.3 17.8 20.6 17.6 29.1 16.0 11.4 130.9 0.4 7.0 6.4 115.1 30.1 17.1 23.7 10.2 14.3 44.3 47.0 27.6 35.5 9.2 0.3 143.7 9.8 64.5 0.5 35.4 13.8 24.3 19.8 4.6 22.8 53.1 130.6 68.1 19.9 38.7 0.0 42.7 21.0 65.2 5.1 0.0 46.4 19.5 22.4 1.0 2.5 1.2 13.1 3.0 14.2 21.5 0.7 53.8 0.0 64.3 6.0 82.4 48.8 4.9 1.3 8.9 50.5 8.2 33.0 24.7 19.7 36.9 47.2 11.0 18.0 27.5 5.5 18.7 1.0 24.5 25.1 5.6 PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 392.7;Hepatic stellate cells: 779.6;Leydig cells: 1092.6;Peritubular cells: 398.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 168.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cell line enhanced" "Detected in many" "ASC diff: 710.0;ASC TERT1: 351.8;HSkMC: 438.1;U-2197: 660.4" "Low region specificity" "Detected in all" HPA072751 Approved Supported "Golgi apparatus" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "HPA072751: AB_2686555" "unprognostic (2.50e-2)" "unprognostic (3.94e-1)" "unprognostic (1.81e-1)" "unprognostic (1.65e-1)" "unprognostic (2.71e-1)" "unprognostic (2.22e-3)" "unprognostic (5.86e-3)" "unprognostic (7.25e-2)" "unprognostic (1.59e-1)" "unprognostic (3.75e-2)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.59e-4)" "unprognostic (3.16e-2)" "unprognostic (1.74e-1)" "unprognostic (3.54e-2)" "unprognostic (2.09e-1)" 168.4 53.0 93.9 33.6 94.2 13.1 139.8 87.3 105.9 294.6 50.7 56.7 24.0 107.2 56.2 51.3 122.5 66.3 84.6 88.3 90.6 91.4 182.0 87.0 22.4 107.5 108.1 81.9 36.8 130.2 23.1 225.5 87.7 102.8 41.8 19.0 76.2 169.7 50.9 82.1 45.8 65.6 86.8 23.3 66.0 37.3 113.2 29.8 327.6 63.0 19.9 139.2 142.8 88.6 3.3 10.8 14.1 1.5 710.0 351.8 34.5 39.3 39.7 35.5 17.4 31.8 6.2 5.2 4.6 59.3 39.4 5.9 2.1 0.8 7.4 0.0 9.4 1.3 4.4 44.5 17.3 0.1 0.0 438.1 3.0 34.2 28.6 25.1 34.1 0.4 2.9 0.1 39.0 3.2 0.1 0.5 43.3 9.2 42.6 0.1 0.1 1.7 6.1 32.6 0.4 28.1 12.4 16.1 4.2 42.6 5.2 0.0 21.6 176.2 14.4 660.4 1.8 0.0 0.0 0.0 31.0 1.7 12.7 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 93.9 94.2 87.3 105.9 88.3 90.6 107.5 108.1 87.7 86.8 113.2 88.6 148.5 25.6 18.9 0.0 7.2 0.0 19.8 0.0 35.3 3.9 12.2 31.2 0.0 44.3 13.0 22.0 0.0 127.0 1.1 8.1 21.5 21.5 7.9 13.9 139.4 148.3 2.4 8.0 0.0 9.2 9.8 392.7 5.6 16.3 3.8 8.1 779.6 132.6 38.8 0.0 0.0 8.5 0.0 35.2 0.0 28.3 1092.6 14.9 0.0 0.0 0.9 136.0 0.0 0.0 0.0 7.9 5.9 398.7 7.1 20.8 15.5 21.3 4.4 4.1 138.1 179.7 107.2 4.5 3.4 16.4 0.0 214.9 5.0 22.4 7.2 20.1 PLS1 "I-plastin, Plastin-1" ENSG00000120756 "Plastin 1" Q14651 3 142596393-142713664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 315.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 471.4;Intestinal goblet cells: 147.9;Paneth cells: 200.5;Proximal enterocytes: 335.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 36.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.6;NK-cells: 3.2;T-cells: 2.6" "Cell line enhanced" "Detected in many" "A-431: 90.0;BEWO: 112.3;OE19: 166.4;RPTEC TERT1: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055744, HPA061936" Enhanced NA NA 56000000 "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA055744: AB_2682903, HPA061936: " "unprognostic (1.29e-1)" "unprognostic (2.61e-1)" "unprognostic (3.15e-3)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (4.84e-4)" "unprognostic (3.14e-2)" "prognostic favorable (8.76e-6)" "unprognostic (1.99e-2)" "unprognostic (8.64e-2)" "unprognostic (7.22e-2)" "unprognostic (3.82e-2)" 1.6 3.9 0.8 18.8 1.3 7.4 5.7 2.7 2.2 10.1 11.7 144.2 191.6 3.3 3.1 9.6 7.7 27.7 1.2 1.1 1.4 26.7 27.5 14.8 1.7 3.3 0.3 0.9 12.2 15.7 6.2 1.5 3.2 3.1 139.1 24.9 9.1 1.9 0.9 3.6 315.6 4.3 0.3 0.9 45.8 7.5 0.4 5.9 7.7 0.9 2.9 19.6 3.7 1.4 90.0 69.2 4.8 10.4 0.7 0.0 112.3 1.7 2.3 9.4 20.1 31.7 68.8 15.2 35.8 0.1 31.9 18.9 18.8 28.7 20.0 5.5 27.0 27.2 10.2 11.4 0.9 13.0 1.7 0.1 4.7 17.8 11.4 14.8 4.5 16.4 11.8 1.7 1.1 21.0 21.4 7.0 18.9 166.4 25.9 8.7 20.3 12.7 143.6 81.7 24.1 9.7 10.0 7.0 7.8 13.3 55.6 2.2 1.2 1.1 11.3 3.5 21.3 12.7 12.6 18.1 3.2 12.8 3.5 1.9 0.2 2.6 1.5 0.2 2.0 0.3 1.8 2.0 0.4 0.3 2.2 2.6 1.8 3.2 0.2 0.5 1.3 1.0 0.8 1.3 2.7 2.2 1.1 1.4 3.3 0.3 3.2 0.3 0.4 1.4 0.6 54.5 38.0 1.3 1.6 2.9 4.1 23.2 2.8 3.4 9.7 4.2 3.1 54.3 46.8 44.1 16.7 5.8 0.7 471.4 21.5 21.8 64.3 22.2 1.8 0.7 53.9 5.9 18.7 34.0 1.9 1.1 50.0 26.8 8.9 32.3 1.1 31.5 0.6 5.0 25.2 147.9 24.4 1.6 1.0 20.5 1.2 1.4 1.8 5.6 0.8 2.8 0.0 4.0 3.1 70.2 200.5 0.0 2.8 6.8 335.1 40.6 42.2 13.4 0.0 1.2 1.9 4.6 4.1 7.6 3.3 1.4 1.8 1.3 85.2 20.7 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 PNPLA4 "DXS1283E, GS2, iPLA2eta" ENSG00000006757 "Patatin like phospholipase domain containing 4" P41247 X 7898247-7927739 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 95.9;Proximal tubular cells: 126.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003656 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA003656: AB_1079033" "unprognostic (2.97e-1)" "unprognostic (2.45e-1)" "unprognostic (4.17e-3)" "unprognostic (3.08e-2)" "prognostic unfavorable (5.29e-4)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.15e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (6.30e-2)" "unprognostic (7.83e-2)" "unprognostic (2.27e-1)" "prognostic favorable (2.23e-12)" "unprognostic (5.23e-2)" "unprognostic (6.71e-3)" "unprognostic (6.30e-2)" "unprognostic (2.12e-1)" 20.8 27.6 11.9 9.7 12.6 8.7 22.6 12.0 11.8 13.9 16.9 15.4 18.9 14.0 18.1 21.0 24.7 9.4 42.1 11.1 14.2 41.2 40.1 9.8 10.8 12.1 13.5 22.4 28.8 25.2 13.5 8.0 12.4 12.8 12.3 16.8 26.9 10.8 77.9 15.0 11.4 12.1 12.5 9.4 19.5 7.8 15.6 16.3 29.9 66.0 10.2 8.9 13.3 11.9 44.7 18.1 2.8 44.4 0.9 0.5 11.9 13.7 1.5 23.0 14.1 18.1 16.1 13.9 0.1 4.5 0.3 25.7 0.0 45.6 39.2 0.4 32.0 10.0 32.8 38.6 28.6 17.8 14.1 29.5 45.7 11.7 27.3 5.5 16.2 0.3 39.9 0.5 0.3 11.8 0.3 17.2 46.9 30.7 38.0 0.3 0.2 15.6 30.6 20.3 25.3 12.7 41.2 16.8 23.7 49.7 26.1 13.0 9.4 0.2 11.4 35.5 0.2 20.3 0.3 27.0 0.2 0.1 3.7 7.4 11.4 9.7 6.1 13.5 7.0 14.7 8.7 6.7 22.2 16.7 11.3 10.8 0.7 11.9 12.5 16.3 6.0 9.3 11.9 12.6 12.0 11.8 11.1 14.2 12.1 13.5 12.4 12.5 15.6 11.9 10.7 9.6 12.5 3.3 8.2 11.9 16.7 46.0 17.6 11.3 38.2 33.5 55.0 20.0 24.3 20.2 0.0 28.7 7.8 31.2 95.9 34.2 3.1 35.9 20.6 10.6 19.8 15.6 2.8 48.7 21.3 14.6 13.7 15.5 8.2 17.3 13.2 62.1 28.7 10.1 3.6 30.6 38.7 9.2 10.2 3.7 16.4 12.1 17.8 1.0 13.3 36.1 6.2 2.5 1.0 39.8 25.1 20.3 14.2 15.3 47.6 126.4 31.0 15.0 6.6 6.6 14.6 22.2 21.4 24.0 16.8 14.0 6.4 49.0 32.3 16.0 PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 88.8" "Cell type enhanced" "Detected in many" "Distal tubular cells: 62.6;Hepatocytes: 53.4;Proximal tubular cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 450000 "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA023204: AB_1855506, HPA027776: AB_10601246" "unprognostic (1.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-2)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-2)" "unprognostic (6.65e-2)" "unprognostic (8.34e-2)" "unprognostic (2.02e-3)" "unprognostic (7.47e-3)" "unprognostic (8.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.74e-1)" 7.3 15.8 16.5 6.2 15.9 3.5 10.6 16.7 22.0 7.0 12.9 8.8 10.2 5.0 11.6 10.7 10.1 6.6 13.2 16.0 21.9 35.1 88.8 6.4 6.9 19.1 21.2 5.8 10.9 26.6 9.2 7.0 20.6 8.0 8.6 5.4 10.4 7.8 21.1 6.7 9.6 6.1 16.5 7.2 8.6 6.6 20.6 5.8 17.8 19.6 7.7 6.7 7.3 14.3 37.9 30.9 2.4 5.8 15.3 11.7 0.0 12.2 7.7 14.0 11.9 51.1 27.6 35.2 57.4 12.7 5.5 22.0 19.4 34.7 20.3 43.4 16.4 24.6 13.9 53.6 16.3 22.6 16.6 15.4 26.9 25.8 32.7 13.1 18.0 26.1 24.4 12.2 16.5 28.3 25.3 7.8 4.5 37.4 37.1 18.8 10.4 26.2 40.2 19.5 12.1 9.5 11.2 18.6 10.7 8.5 32.4 9.1 19.1 22.6 12.8 22.2 26.2 27.8 34.0 19.0 18.4 19.2 11.7 2.5 12.3 2.8 7.2 17.7 8.2 6.7 6.3 7.6 13.5 5.3 8.2 8.1 1.1 7.9 11.9 9.8 7.0 10.3 16.5 15.9 16.7 22.0 16.0 21.9 19.1 21.2 20.6 16.5 20.6 14.3 7.6 12.8 13.9 7.5 3.9 1.5 6.7 5.0 5.7 1.1 16.2 14.4 1.9 18.6 6.8 12.9 4.2 8.4 7.8 7.3 62.6 18.2 0.8 11.2 6.4 5.9 3.6 7.4 4.2 15.6 1.9 5.3 4.6 13.3 12.7 8.8 6.4 53.4 17.2 3.3 6.2 11.6 2.0 11.4 2.4 0.9 9.9 10.6 1.8 2.8 8.6 7.1 3.1 2.5 3.2 15.0 8.9 6.0 4.9 9.0 20.2 86.3 5.9 1.9 0.0 4.1 3.8 0.7 1.3 7.2 2.3 6.3 4.7 19.5 15.4 5.0 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 397.2;Proximal tubular cells: 316.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 17000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA031361: AB_10602150, HPA031363: AB_2673844" "unprognostic (1.49e-1)" "unprognostic (6.71e-2)" "unprognostic (8.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.84e-3)" "unprognostic (1.68e-2)" "prognostic unfavorable (5.96e-5)" "unprognostic (2.71e-1)" "unprognostic (7.79e-3)" "unprognostic (9.13e-3)" "unprognostic (3.24e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-2)" "unprognostic (6.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.80e-1)" "unprognostic (4.30e-2)" 51.0 62.7 28.2 34.6 29.3 27.1 65.0 29.8 34.6 44.2 36.8 63.5 58.0 35.8 71.0 48.4 31.7 43.1 42.5 28.6 32.0 88.1 99.6 39.8 43.5 30.1 28.8 30.2 66.9 59.8 27.8 38.0 29.1 52.3 58.0 22.4 59.3 44.2 45.9 47.0 56.4 29.0 31.6 42.2 64.7 15.0 29.9 27.8 64.8 40.4 38.2 43.3 40.1 32.9 83.4 34.3 17.2 28.8 52.3 55.0 72.1 40.7 43.3 49.1 44.2 30.7 93.3 22.6 80.7 46.2 30.3 48.8 11.5 62.5 40.3 66.2 35.1 39.9 34.7 31.3 72.5 39.9 69.4 48.8 98.9 35.8 62.4 58.2 48.3 29.9 16.9 17.0 50.5 47.3 20.4 40.1 22.6 70.0 49.8 22.6 18.8 45.3 106.2 70.7 23.0 25.0 47.9 113.2 129.4 50.2 56.7 167.8 31.1 28.2 41.1 42.9 46.5 58.6 37.3 17.5 12.6 44.4 61.0 298.8 231.5 325.6 114.5 245.4 135.2 171.5 141.1 128.0 195.9 182.4 149.5 132.9 159.5 185.6 237.2 135.8 160.9 262.8 28.2 29.3 29.8 34.6 28.6 32.0 30.1 28.8 29.1 31.6 29.9 32.9 61.0 57.7 84.1 5.9 62.6 23.3 42.3 99.4 42.7 12.1 91.3 100.2 104.3 84.4 90.8 64.4 6.2 172.2 52.6 129.2 397.2 96.5 3.5 66.7 43.9 48.7 31.3 29.0 7.4 136.8 131.0 52.9 61.7 59.3 57.0 52.8 44.6 120.1 107.4 11.8 7.0 124.9 103.7 84.4 44.3 4.6 60.6 76.3 81.8 6.5 127.0 64.8 79.3 8.0 8.7 98.5 125.2 63.6 41.8 51.7 159.7 316.3 63.2 28.0 26.3 26.2 48.9 10.3 20.8 66.3 36.2 134.6 62.5 103.2 101.2 60.1 PPIC CYPC ENSG00000168938 "Peptidylprolyl isomerase C" P45877 5 123023250-123036725 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 251.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 229.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039163 Approved "Intracellular and membrane" NA NA 3700000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA039163: AB_2676374" "unprognostic (7.81e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" "unprognostic (7.49e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (3.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.31e-1)" "unprognostic (3.37e-1)" "unprognostic (1.70e-1)" "unprognostic (2.38e-1)" "unprognostic (4.27e-2)" "unprognostic (2.43e-2)" 37.0 20.6 5.3 16.4 5.6 0.2 30.4 6.8 7.0 42.3 12.2 41.4 37.3 31.0 36.5 46.8 14.8 33.5 44.4 5.2 5.8 24.9 28.9 27.0 7.6 6.4 6.3 16.2 30.3 20.9 6.2 48.3 6.2 23.4 49.9 4.9 31.7 24.0 41.2 20.2 32.3 45.2 6.1 7.7 22.4 9.0 6.7 5.8 47.2 33.3 14.2 45.8 28.8 5.8 19.6 16.8 6.4 136.2 229.7 104.6 26.9 54.4 42.3 27.8 56.7 28.1 128.6 0.0 94.2 147.1 83.3 21.9 18.9 68.6 22.1 0.1 33.1 27.8 60.7 32.8 58.9 0.0 14.7 65.8 51.5 32.5 34.0 49.9 58.1 0.0 7.9 0.0 20.1 116.5 0.1 0.3 11.6 120.9 29.0 0.0 14.5 0.0 87.7 67.0 8.5 14.9 106.7 51.1 12.1 77.8 72.0 61.8 64.8 52.9 32.7 18.5 23.9 0.2 0.1 0.4 45.9 0.2 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 5.6 6.8 7.0 5.2 5.8 6.4 6.3 6.2 6.1 6.7 5.8 214.1 32.1 16.5 6.2 1.6 47.4 52.3 251.7 30.7 16.9 63.9 47.5 46.4 61.5 149.0 73.5 4.2 60.1 0.6 134.0 29.4 201.5 1.7 52.4 94.8 106.5 12.7 0.0 0.8 126.4 65.2 198.2 55.0 50.8 1.3 54.2 80.7 57.8 43.2 0.0 2.2 177.1 207.5 4.2 40.3 4.2 112.5 6.9 32.0 5.6 3.2 2.8 0.0 1.0 0.3 90.3 181.0 100.1 0.6 48.2 189.0 81.7 110.5 4.4 39.5 22.7 87.5 41.6 37.8 118.6 49.3 25.0 3.4 61.2 117.0 81.5 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R14A "CPI-17, PPP1INL" ENSG00000167641 "Protein phosphatase 1 regulatory inhibitor subunit 14A" Q96A00 19 38251237-38256532 "Plasma proteins, Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 492.0;intestine: 450.3" "Cell type enhanced" "Detected in many" "Adipocytes: 332.5;Granulosa cells: 435.0;Leydig cells: 341.1;Peritubular cells: 656.0;Sertoli cells: 979.5;Smooth muscle cells: 465.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 299.4;naive B-cell: 283.9;plasmacytoid DC: 246.9" "Group enriched" "Detected in many" 24 "B-cells: 299.4;dendritic cells: 246.9" "Group enriched" "Detected in some" 4 "A549: 164.1;EFO-21: 112.2;K-562: 64.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005044, CAB009803, HPA042097, HPA054534" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA 880000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Nuclear bodies" "CAB005044: AB_562091, CAB009803: AB_2168720, HPA042097: AB_2677846, HPA054534: AB_2682518" "unprognostic (5.40e-2)" "unprognostic (4.00e-3)" "unprognostic (4.02e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-1)" "unprognostic (8.92e-3)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (1.96e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.25e-5)" "prognostic unfavorable (7.12e-4)" "unprognostic (4.13e-1)" "unprognostic (5.81e-2)" "unprognostic (2.22e-2)" 134.0 144.2 175.2 22.1 347.5 2.9 111.9 321.5 226.5 149.7 63.2 450.3 18.6 273.5 5.2 47.6 153.7 14.8 94.6 175.2 219.6 53.3 17.9 163.1 2.6 402.3 322.9 125.1 31.1 2.8 12.6 34.1 336.3 142.0 12.6 0.3 19.0 86.1 27.5 28.6 82.1 57.2 222.0 101.2 140.3 77.6 365.3 1.7 25.8 12.3 1.4 301.6 106.1 492.0 0.0 164.1 0.4 0.0 1.0 0.0 6.1 10.8 0.0 0.1 0.0 12.8 0.2 0.0 112.2 1.0 0.0 0.5 13.6 0.2 0.0 1.4 0.0 25.5 0.0 0.0 4.6 0.0 0.0 0.3 0.0 1.4 0.0 0.0 0.1 0.0 64.5 0.3 0.0 0.8 0.0 0.3 4.9 0.0 0.0 0.2 2.4 0.4 0.4 0.0 3.5 0.2 0.0 0.0 0.1 9.2 0.0 0.4 0.4 0.0 0.8 0.4 0.0 0.4 0.0 0.5 0.2 0.0 0.1 11.3 0.6 1.2 0.1 0.7 0.2 299.4 0.2 0.4 44.3 283.9 0.6 0.1 1.7 8.7 0.2 246.9 0.2 21.6 175.2 347.5 321.5 226.5 175.2 219.6 402.3 322.9 336.3 222.0 365.3 492.0 332.5 0.0 1.1 1.3 29.9 9.6 3.0 1.2 3.4 0.4 8.8 209.8 19.6 2.8 0.7 0.0 0.0 48.3 48.7 32.7 0.0 0.7 14.1 15.4 239.5 108.5 1.8 34.7 0.5 10.9 7.4 66.8 2.0 10.8 3.8 435.0 224.5 2.3 9.5 0.0 0.6 0.4 0.0 5.6 24.6 42.1 341.1 41.4 8.8 14.0 66.1 0.5 4.1 3.5 155.6 2.2 2.6 656.0 4.8 2.4 3.8 0.3 0.0 1.6 979.5 8.7 465.2 9.9 46.2 0.6 8.0 26.4 3.7 66.0 0.4 1.2 PPP1R7 sds22 ENSG00000115685 "Protein phosphatase 1 regulatory subunit 7" Q15435 2 241149576-241183652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 968.8;Late spermatids: 1709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA034500, HPA034501" Supported Approved Nucleoli NA NA 960000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA034500: AB_2674192, HPA034501: AB_10670965" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (4.38e-1)" "unprognostic (8.07e-3)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (4.51e-3)" "unprognostic (1.23e-1)" 59.0 55.9 71.3 54.4 94.7 68.1 50.2 65.5 82.4 46.4 68.3 66.0 58.8 48.5 61.4 80.3 81.3 40.2 100.5 77.5 69.4 64.6 76.0 53.9 78.7 67.2 67.2 37.5 60.0 55.8 42.6 44.5 65.7 94.5 64.2 58.0 63.1 54.0 100.4 64.3 61.0 55.0 66.5 48.7 58.9 158.2 67.2 66.8 65.1 64.4 80.8 58.9 52.9 75.1 117.6 69.5 77.4 98.3 149.7 149.0 106.4 126.3 114.7 85.2 119.8 38.1 145.6 60.0 37.1 108.9 128.0 112.1 127.9 119.6 130.2 156.4 126.1 105.1 112.4 151.4 96.3 147.0 105.9 116.0 92.7 101.1 74.2 115.7 128.5 121.0 108.0 86.2 202.0 155.8 132.0 112.6 106.3 185.7 64.5 90.4 200.9 121.9 159.6 116.7 104.6 82.8 67.6 157.4 120.3 86.4 93.8 156.7 127.7 76.8 72.5 146.1 103.4 90.8 59.6 162.8 215.2 154.1 103.7 107.9 84.9 108.9 64.6 87.6 68.3 71.6 76.5 77.1 81.3 66.5 58.5 67.6 66.5 75.8 96.2 48.4 121.5 89.9 71.3 94.7 65.5 82.4 77.5 69.4 67.2 67.2 65.7 66.5 67.2 75.1 50.5 57.7 54.5 17.6 47.9 27.8 48.6 126.2 25.6 41.5 44.6 36.8 98.4 45.8 105.5 44.1 16.7 89.6 46.9 53.4 121.3 90.6 968.8 83.6 39.3 45.9 25.7 48.0 33.8 145.9 92.4 47.5 34.7 53.4 59.5 48.9 32.9 49.9 100.5 32.0 19.4 68.7 109.9 40.7 46.3 1709.4 51.0 49.4 87.2 13.1 63.7 78.6 80.3 18.1 21.9 94.5 71.3 67.4 54.5 52.1 81.7 120.8 112.2 58.9 72.3 35.1 65.6 315.5 122.5 45.9 38.1 71.6 57.9 117.2 55.3 56.0 PPP2CA "PP2AC, PP2Calpha" ENSG00000113575 "Protein phosphatase 2 catalytic subunit alpha" P67775 5 134194332-134226073 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Meiosis "Hydrolase, Protein phosphatase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003848, HPA043236" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003848: AB_562203, HPA043236: AB_2678379" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.60e-2)" "unprognostic (3.35e-3)" "unprognostic (1.26e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (7.33e-5)" "unprognostic (1.59e-3)" "unprognostic (1.57e-1)" "unprognostic (2.02e-1)" "unprognostic (1.34e-2)" "unprognostic (1.31e-1)" "unprognostic (5.24e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-1)" "unprognostic (6.14e-2)" "unprognostic (1.57e-1)" 47.9 53.1 52.1 42.9 55.1 124.8 46.6 60.6 66.3 38.9 44.9 51.4 46.1 46.6 36.1 71.5 39.0 44.6 90.1 57.8 53.5 57.3 62.1 39.4 58.6 48.6 51.4 30.0 44.3 87.1 26.1 52.2 53.7 37.8 47.1 58.6 36.5 40.4 75.3 54.1 44.5 57.8 54.7 40.0 41.3 34.7 53.6 92.4 48.1 73.1 76.7 75.4 41.0 59.5 157.0 128.8 180.8 97.9 92.1 98.2 126.2 144.1 123.3 214.8 215.4 249.1 119.6 136.5 131.7 134.4 242.9 79.7 175.6 208.6 250.2 123.9 100.1 96.9 142.4 156.5 136.3 97.1 84.2 91.7 141.5 169.0 166.6 107.0 153.5 135.1 97.2 99.1 165.1 112.5 154.9 95.0 98.9 123.6 77.3 136.5 179.6 132.6 130.0 173.4 142.9 99.6 148.9 55.1 166.9 179.7 112.2 112.3 109.2 123.3 69.1 99.6 206.5 88.5 171.6 217.0 83.2 125.9 130.3 43.0 64.7 75.6 46.8 63.1 59.2 53.1 53.2 62.5 77.3 54.7 60.6 57.2 71.3 75.5 67.0 41.5 72.4 95.8 52.1 55.1 60.6 66.3 57.8 53.5 48.6 51.4 53.7 54.7 53.6 59.5 58.7 51.3 47.6 27.1 103.3 239.0 187.4 90.1 121.8 43.9 93.6 53.0 111.2 55.8 63.1 57.0 22.9 152.1 89.0 68.7 107.6 109.7 34.6 85.8 83.2 81.1 87.1 89.0 36.6 87.6 171.3 78.0 77.5 106.1 62.2 44.6 51.8 65.9 111.4 50.5 35.7 62.0 69.2 88.2 194.6 29.8 38.5 95.8 104.9 24.4 115.6 62.9 51.5 36.7 48.9 101.7 56.6 45.5 120.9 143.3 64.9 114.8 53.0 31.4 19.7 76.8 97.6 91.4 85.8 112.4 234.4 309.8 110.6 53.3 69.7 176.7 PPP2R1A "PP2A-Aalpha, PP2AA, PR65A" ENSG00000105568 "Protein phosphatase 2 scaffold subunit Aalpha" P30153 19 52190048-52229518 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromosome partition" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018599 Approved Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "CAB018599: AB_628178" "unprognostic (1.78e-1)" "unprognostic (2.31e-2)" "unprognostic (4.52e-2)" "unprognostic (2.87e-1)" "unprognostic (6.67e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.76e-4)" "prognostic unfavorable (2.50e-4)" "unprognostic (4.30e-2)" "unprognostic (3.06e-1)" "unprognostic (6.48e-3)" "unprognostic (8.28e-2)" "prognostic favorable (1.20e-4)" "unprognostic (1.97e-1)" "unprognostic (3.57e-2)" "unprognostic (1.70e-2)" "unprognostic (9.19e-2)" 98.5 300.7 305.0 60.5 311.1 58.1 98.7 292.0 394.2 126.9 261.4 115.7 91.5 126.8 101.0 164.4 126.8 63.2 322.8 342.6 299.4 156.9 106.0 87.5 72.7 308.9 301.1 163.7 100.7 129.9 123.9 69.1 312.8 123.3 82.2 89.8 99.8 92.2 239.7 119.3 98.5 96.0 280.1 87.6 106.0 67.2 331.7 76.9 107.9 170.7 90.0 123.5 121.9 299.2 153.6 248.4 210.9 182.0 166.9 173.4 105.3 130.3 173.2 174.1 151.1 129.3 122.1 132.5 91.0 213.9 95.7 108.8 228.0 197.9 100.6 101.3 562.8 99.6 126.9 148.2 152.6 105.6 93.1 234.3 163.8 163.5 149.2 162.9 167.9 92.1 114.3 96.8 196.3 178.6 159.6 215.4 204.6 162.2 218.4 148.6 118.3 152.5 285.0 251.7 153.3 161.3 149.0 160.1 100.3 136.3 141.9 197.3 153.1 133.2 120.5 65.7 154.2 96.9 151.5 160.0 143.1 109.7 170.5 172.6 172.0 169.4 143.9 212.2 131.0 143.1 126.3 134.3 192.8 157.1 101.6 119.6 103.7 228.6 199.0 119.7 177.5 255.6 305.0 311.1 292.0 394.2 342.6 299.4 308.9 301.1 312.8 280.1 331.7 299.2 55.3 44.8 35.4 21.5 76.0 70.4 99.0 178.0 56.9 114.0 64.5 71.1 100.2 74.4 99.5 119.5 25.0 203.7 47.3 157.0 117.4 213.5 4.4 77.5 79.7 72.4 107.0 39.7 27.4 155.7 259.9 85.7 77.5 100.7 68.5 96.7 65.0 52.8 146.2 144.7 39.5 128.8 144.5 68.1 39.3 10.4 72.4 58.0 53.4 17.8 103.7 118.0 62.8 25.6 29.9 168.2 189.0 85.4 60.3 88.3 147.5 135.3 80.6 61.5 78.9 49.2 90.3 16.5 68.8 74.4 63.2 182.0 64.2 99.7 185.2 104.2 PRDX2 "MGC4104, NKEFB, PRP, PRX2, PRXII, TDPX1, TSA" ENSG00000167815 "Peroxiredoxin 2" P32119 19 12796820-12801800 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1316.7;Erythroid cells: 3153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB008713 Approved NA NA 800000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" "CAB008713: AB_1620974" "unprognostic (1.12e-1)" "unprognostic (1.98e-3)" "unprognostic (8.58e-2)" "unprognostic (4.40e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (2.44e-1)" "unprognostic (2.59e-2)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.26e-2)" "unprognostic (9.18e-2)" "prognostic favorable (5.66e-11)" "unprognostic (7.01e-3)" "unprognostic (2.15e-1)" "unprognostic (3.51e-2)" "unprognostic (1.41e-1)" 199.0 622.0 350.8 88.3 366.6 686.7 159.7 408.2 461.5 167.8 365.6 208.1 251.7 178.8 144.5 271.8 153.5 133.9 704.0 369.6 400.0 287.7 310.2 109.1 118.3 407.5 380.4 218.2 201.7 454.5 314.6 87.8 408.2 175.3 141.5 207.1 200.1 124.4 722.9 260.7 201.1 127.0 357.0 118.1 226.6 32.8 399.1 181.3 156.3 847.9 129.2 163.6 171.6 355.5 420.4 1.1 553.9 721.3 79.5 54.2 408.4 189.0 188.0 253.9 143.4 438.1 102.8 122.7 430.9 185.0 30.2 389.5 354.7 309.7 72.9 528.5 561.4 222.6 537.4 665.1 212.4 0.7 1.4 233.6 140.5 191.1 93.0 327.6 238.8 255.3 485.7 187.0 98.7 763.3 500.1 190.2 409.1 289.6 789.4 485.8 0.7 593.0 343.1 450.0 683.8 538.5 449.5 454.9 153.7 100.7 408.0 318.0 105.7 188.2 156.9 526.7 417.7 226.3 242.1 573.5 178.9 75.5 43.8 35.4 170.0 85.6 436.1 129.4 460.6 375.2 589.8 446.2 211.6 288.5 594.7 460.9 22.4 213.2 148.0 124.5 697.4 686.6 350.8 366.6 408.2 461.5 369.6 400.0 407.5 380.4 408.2 357.0 399.1 355.5 192.2 22.4 36.7 39.5 117.5 221.3 255.6 877.7 187.2 317.9 271.2 322.2 37.1 265.9 347.7 279.6 100.1 692.8 83.5 367.4 1316.7 329.5 3.1 138.6 218.5 130.3 333.7 3153.4 31.8 167.2 558.8 204.3 214.6 197.7 47.0 466.0 137.8 489.7 234.0 215.4 50.8 360.7 754.8 63.8 128.8 13.0 293.9 58.7 281.1 23.4 61.4 531.2 56.7 41.7 29.1 179.6 250.6 321.2 263.4 169.3 765.6 1097.9 152.7 373.2 157.8 142.4 273.2 4.8 7.7 368.5 229.4 508.4 144.4 816.6 475.7 243.1 PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 1060.4;Proximal tubular cells: 937.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008656, HPA041488, CAB079909" Enhanced Supported Mitochondria NA NA 1600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008656: AB_1620979, CAB079909: AB_2809998, HPA041488: AB_2677508" "unprognostic (8.29e-2)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (1.72e-3)" "unprognostic (4.62e-3)" "unprognostic (2.40e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-2)" "unprognostic (1.29e-2)" "unprognostic (9.48e-2)" "unprognostic (6.03e-3)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" 165.7 335.3 92.4 96.0 92.6 82.3 138.3 101.3 116.0 103.4 139.2 133.3 137.8 87.0 120.8 83.3 116.7 88.0 278.2 95.2 104.5 385.7 571.2 74.9 108.4 97.2 97.1 74.9 96.2 223.8 60.0 126.3 99.0 126.7 139.8 52.5 132.1 131.7 376.0 38.0 132.1 130.0 100.4 76.3 97.5 48.3 98.6 98.3 176.7 402.7 104.0 112.8 65.1 102.7 350.6 392.2 234.1 267.3 241.7 259.8 145.9 244.8 414.8 364.5 380.7 303.4 339.9 407.2 208.8 290.8 173.4 155.5 391.5 296.1 408.8 401.5 411.4 183.7 149.7 542.4 252.5 347.8 212.7 306.8 186.4 292.1 269.7 261.2 268.6 245.2 230.0 82.5 338.7 140.2 265.1 292.7 218.9 264.0 229.3 276.5 339.7 281.5 623.8 164.6 103.0 149.2 259.8 346.1 332.2 201.0 179.6 411.5 190.5 118.3 178.1 170.9 323.1 128.0 200.7 327.0 185.7 507.4 107.3 144.4 429.1 246.9 110.5 369.5 142.7 179.9 145.6 134.6 382.1 149.8 149.5 134.0 239.9 132.8 333.9 214.8 205.7 510.2 92.4 92.6 101.3 116.0 95.2 104.5 97.2 97.1 99.0 100.4 98.6 102.7 61.4 48.1 74.5 14.4 65.1 69.8 117.8 274.0 81.4 27.5 145.2 105.2 236.5 131.5 119.0 147.1 10.4 328.4 50.6 84.5 1060.4 124.5 5.0 105.1 76.0 78.3 110.9 132.8 15.4 75.1 212.0 100.8 116.7 77.3 52.6 131.0 73.2 390.0 247.6 40.4 15.4 132.5 221.8 164.2 96.0 10.5 77.3 127.9 133.4 10.3 158.4 76.9 39.1 12.5 18.8 63.8 99.3 101.2 153.7 95.1 176.1 937.8 163.4 24.8 72.3 63.1 105.3 11.2 23.2 146.4 52.6 155.0 56.1 440.0 207.0 119.6 PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.6;lung: 16.5;lymphoid tissue: 49.4" "Cell type enhanced" "Detected in some" "dendritic cells: 542.1;NK-cells: 1231.7;T-cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 900.4;MAIT T-cell: 628.8;memory CD8 T-cell: 499.1;naive CD8 T-cell: 313.0;NK-cell: 656.8" "Group enriched" "Detected in all" 50 "NK-cells: 656.8;T-cells: 900.4" "Cell line enriched" "Detected in some" 11 "HDLM-2: 240.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" NA NA 2100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB002436: AB_563955, HPA037940: AB_2675747" "unprognostic (6.11e-3)" "unprognostic (1.26e-2)" "unprognostic (1.71e-1)" "prognostic favorable (2.09e-4)" "unprognostic (1.87e-2)" "prognostic favorable (3.54e-4)" "unprognostic (6.98e-3)" "unprognostic (2.62e-1)" "unprognostic (1.44e-3)" "unprognostic (1.69e-2)" "unprognostic (5.22e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.08e-5)" "unprognostic (7.38e-2)" "unprognostic (2.70e-1)" "unprognostic (7.97e-3)" "unprognostic (5.22e-3)" 5.0 2.0 0.7 7.6 0.7 28.6 2.7 0.7 1.3 1.3 1.3 2.2 2.3 3.5 1.1 1.9 1.9 4.2 2.2 0.6 0.6 1.7 6.3 16.5 20.3 1.4 0.7 1.0 1.0 0.5 0.9 2.7 1.0 1.5 1.4 0.0 2.3 1.2 2.6 0.9 5.2 2.0 1.3 49.4 4.7 0.6 1.0 5.8 2.6 1.5 4.9 3.8 1.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 240.1 0.0 1.4 0.0 7.4 0.0 0.3 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 22.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 5.2 1.9 0.9 900.4 1.7 628.8 4.0 125.8 499.1 2.0 3.5 52.1 313.0 15.4 656.8 2.6 2.9 108.8 587.5 0.7 0.7 0.7 1.3 0.6 0.6 1.4 0.7 1.0 1.3 1.0 1.0 3.1 3.2 13.6 0.0 4.4 0.4 0.1 0.0 0.6 0.0 0.5 0.5 0.8 1.5 2.5 0.0 0.0 0.2 542.1 0.1 0.0 0.3 0.0 0.2 0.3 1.9 0.0 19.0 0.0 0.0 0.1 2.1 7.7 0.4 8.8 0.0 10.8 2.7 0.1 0.0 0.0 0.0 0.0 7.8 2.3 0.0 0.0 5.7 0.0 1.9 7.4 0.0 1231.7 0.0 0.1 0.0 0.0 0.0 88.5 0.1 0.1 1.6 1.5 0.0 0.0 1.1 0.8 0.0 0.0 0.5 0.9 0.7 265.4 0.0 0.1 0.0 PRKCQ ENSG00000065675 "Protein kinase C theta" Q04759 10 6427143-6580301 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 33.6;skeletal muscle: 124.5;tongue: 112.6" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;dendritic cells: 22.4;NK-cells: 32.0;Oligodendrocyte precursor cells: 24.6;Oligodendrocytes: 75.2;T-cells: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 23.0;MAIT T-cell: 18.0;memory CD4 T-cell: 24.5;memory CD8 T-cell: 24.5;naive CD4 T-cell: 19.1;naive CD8 T-cell: 17.9;NK-cell: 13.3;T-reg: 39.7" "Group enriched" "Detected in many" 11 "NK-cells: 13.3;T-cells: 39.7" "Cell line enhanced" "Detected in many" "HEL: 57.8;JURKAT: 40.0;MOLT-4: 43.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065279, HPA073098" Enhanced "Centriolar satellite" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Centriolar satellite" "HPA065279: AB_2685453, HPA073098: AB_2686571" "unprognostic (6.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (2.69e-3)" "unprognostic (2.46e-1)" "unprognostic (8.40e-2)" "unprognostic (2.66e-1)" "unprognostic (1.17e-1)" "unprognostic (3.22e-1)" "unprognostic (5.26e-2)" "unprognostic (7.74e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (3.51e-2)" 0.8 0.7 5.3 5.2 8.5 5.7 0.9 6.1 6.3 1.6 12.1 1.4 1.5 2.5 8.3 2.2 3.9 1.5 0.3 5.5 8.2 10.9 1.0 5.3 12.3 6.5 8.6 1.3 3.4 0.7 0.8 0.2 6.4 1.8 1.7 1.5 1.4 1.1 124.5 0.3 3.3 0.7 5.5 5.0 2.1 1.1 7.2 33.6 14.9 112.6 9.4 2.2 0.6 9.8 0.1 5.3 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.2 0.4 3.4 0.3 0.0 0.0 0.0 0.0 3.3 6.0 0.0 0.0 3.9 57.8 0.0 0.4 0.7 2.8 0.6 0.3 3.5 0.1 0.2 0.0 0.5 40.0 12.8 0.1 0.0 0.0 43.9 8.0 5.8 0.5 0.0 8.5 1.3 0.0 11.6 2.9 0.4 2.1 0.0 0.0 0.0 3.4 0.0 5.8 0.0 0.0 5.6 0.0 0.0 0.1 0.0 0.0 0.0 7.1 0.0 2.4 0.1 0.3 23.0 0.4 18.0 0.1 24.5 24.5 0.2 0.0 19.1 17.9 1.6 13.3 0.0 0.0 39.7 10.5 5.3 8.5 6.1 6.3 5.5 8.2 6.5 8.6 6.4 5.5 7.2 9.8 0.2 3.2 7.0 22.9 0.8 0.0 0.3 0.3 0.6 1.6 0.3 0.3 0.4 0.0 0.7 1.8 0.0 0.0 22.4 0.0 7.9 0.3 2.1 0.5 1.2 0.2 1.8 8.0 13.7 0.8 0.1 0.7 1.5 3.0 1.3 8.2 1.1 0.0 0.5 0.0 14.7 0.5 0.0 1.3 0.5 5.6 0.0 1.7 0.0 7.5 0.8 1.2 32.0 24.6 75.2 0.1 0.1 0.0 10.2 0.2 0.0 0.3 0.9 0.4 0.0 4.2 0.4 1.0 2.2 0.5 0.0 0.0 31.7 0.3 0.4 0.1 PRMT6 "FLJ10559, HRMT1L6" ENSG00000198890 "Protein arginine methyltransferase 6" Q96LA8 1 107056674-107067636 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "MCF7: 308.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059424 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA059424: AB_2684012" "unprognostic (5.17e-3)" "unprognostic (1.48e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (2.68e-1)" "unprognostic (2.55e-1)" "unprognostic (1.36e-3)" "unprognostic (2.13e-2)" "unprognostic (9.72e-2)" "unprognostic (2.53e-2)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (3.15e-2)" "unprognostic (1.03e-1)" "unprognostic (8.34e-2)" "unprognostic (1.01e-1)" "unprognostic (1.73e-3)" 4.9 10.0 5.7 7.2 5.6 4.2 8.0 5.6 5.7 6.1 13.8 7.9 6.1 7.0 8.0 6.8 8.8 6.0 3.9 5.2 6.9 12.0 7.1 4.6 9.6 6.1 6.5 8.6 10.9 9.6 8.4 7.3 5.3 8.5 7.2 6.4 6.5 7.8 1.8 5.6 7.2 5.9 5.5 8.3 7.4 6.6 8.2 10.3 7.0 3.1 8.7 7.9 5.0 6.0 13.6 0.2 25.7 11.3 16.6 18.4 7.0 17.8 13.2 16.9 17.2 17.2 9.2 33.1 24.1 16.5 9.2 18.9 23.9 26.2 13.3 0.0 25.4 20.0 35.6 25.0 16.5 41.6 11.9 17.4 14.2 15.2 15.5 11.4 14.8 18.5 27.1 5.0 15.4 308.1 24.5 14.6 11.1 10.6 24.6 30.8 56.0 12.6 41.3 27.1 47.8 58.3 24.2 34.5 12.1 15.5 24.0 30.7 17.2 12.5 25.5 26.3 26.8 5.4 4.0 5.7 18.4 19.3 10.2 2.1 10.4 1.9 7.9 11.9 9.5 7.4 8.3 7.6 14.1 10.3 11.5 11.9 0.6 17.4 12.0 17.2 9.2 9.3 5.7 5.6 5.6 5.7 5.2 6.9 6.1 6.5 5.3 5.5 8.2 6.0 3.0 0.0 4.4 1.3 6.2 4.5 6.9 9.7 8.6 14.2 8.9 5.0 2.6 5.7 5.8 14.7 0.0 18.3 8.5 3.3 27.4 10.3 1.2 5.2 6.2 4.7 17.5 15.8 1.5 7.4 14.6 6.7 4.6 4.9 1.3 9.4 7.5 2.4 10.0 15.2 2.2 7.4 8.2 7.0 1.6 3.0 8.7 3.8 1.8 3.7 3.9 6.9 3.1 2.0 2.2 4.7 8.5 9.1 2.0 5.1 4.1 18.4 7.4 5.1 13.1 5.9 6.3 9.1 8.1 8.9 6.1 7.1 5.0 13.7 10.3 5.4 PROK2 "BV8, KAL4, MIT1, PK2" ENSG00000163421 "Prokineticin 2" Q9HC23 3 71771655-71785206 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Biological rhythms" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 64.5;lymphoid tissue: 22.5" "Cell type enhanced" "Detected in some" "Erythroid cells: 5.9;Kupffer cells: 8.0;Macrophages: 11.3;monocytes: 6.9;Spermatocytes: 23.8" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.1" "Region enriched" "Detected in many" 7 "cerebral cortex: 13.3" "Immune cell enriched" "Detected in many" 50 "neutrophil: 414.4" "Lineage enriched" "Detected in many" 50 "granulocytes: 414.4" "Cell line enhanced" "Detected in some" "HL-60: 9.2;NB-4: 8.9;NTERA-2: 5.5;U-266/70: 12.0;U-266/84: 20.8;U-937: 8.3" "Group enriched" "Detected in some" 6 "basal ganglia: 2.7;hypothalamus: 1.1;olfactory bulb: 3.5" "Low region specificity" "Detected in all" HPA041408 Approved "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA041408: AB_10964057" "unprognostic (5.24e-2)" "unprognostic (3.13e-3)" "unprognostic (3.51e-3)" "unprognostic (3.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.94e-1)" "unprognostic (2.97e-2)" "unprognostic (9.52e-2)" "unprognostic (4.29e-2)" "unprognostic (9.91e-3)" "unprognostic (6.89e-2)" "unprognostic (5.73e-1)" "unprognostic (1.59e-4)" "unprognostic (2.02e-2)" "unprognostic (1.48e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-2)" 7.2 0.3 0.7 17.7 0.5 64.5 0.3 0.1 13.3 0.4 0.7 0.4 0.3 0.2 0.0 0.4 2.7 1.2 1.0 0.2 0.5 0.6 2.5 13.1 0.2 0.5 1.0 0.2 1.1 0.0 0.4 3.1 1.2 0.2 0.2 0.1 0.3 0.0 0.5 0.1 0.5 1.5 0.2 22.5 0.6 11.4 1.9 1.1 0.5 4.2 0.5 6.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.3 1.6 0.0 0.0 0.0 0.3 8.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 20.8 0.0 0.0 8.3 0.0 0.0 8.2 3.5 3.4 0.7 0.0 0.0 2.7 2.9 0.7 0.0 0.9 5.0 414.4 0.0 0.2 0.3 1.7 3.1 0.7 0.5 0.1 13.3 0.2 0.5 0.5 1.0 1.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 1.8 0.0 0.0 2.5 0.0 0.0 0.0 1.6 0.1 0.1 0.1 0.0 5.9 0.0 0.0 0.0 0.9 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 8.0 0.3 2.8 0.3 11.3 1.8 0.0 6.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 23.8 2.9 0.0 0.0 0.0 3.5 0.1 0.0 0.0 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 320000 "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA043760: AB_2678656, HPA051269: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 22.9 28.0 33.7 30.2 35.0 58.0 21.0 32.4 36.4 20.0 59.3 19.0 11.0 23.7 14.8 13.7 25.9 13.9 22.2 33.7 39.6 27.6 51.5 21.5 42.7 35.4 39.1 30.2 21.7 27.2 23.2 14.6 37.6 21.3 17.9 30.2 16.3 17.4 49.1 12.3 16.7 29.5 34.2 26.2 15.5 13.4 35.2 52.0 44.1 37.9 45.7 23.6 15.2 34.4 93.5 128.9 56.4 69.9 32.7 26.5 18.6 253.2 55.8 146.0 122.6 55.5 36.6 156.9 111.7 94.9 104.1 36.6 176.0 53.8 148.3 79.9 150.9 84.2 140.0 100.3 28.8 153.1 55.6 28.2 30.6 90.2 56.2 96.7 52.3 108.2 137.4 183.5 69.0 51.0 101.2 113.6 213.5 77.2 141.4 117.6 96.3 125.4 60.7 54.2 96.2 52.5 131.5 77.6 57.3 106.4 36.0 61.7 31.2 93.2 45.0 108.3 109.1 61.8 115.1 172.7 50.1 163.6 61.6 8.8 8.9 22.6 26.0 14.3 30.8 29.3 31.7 32.2 11.4 31.0 36.1 30.7 4.7 28.5 15.7 16.3 35.5 21.1 33.7 35.0 32.4 36.4 33.7 39.6 35.4 39.1 37.6 34.2 35.2 34.4 21.0 6.4 10.0 4.6 44.2 31.1 18.4 13.2 12.0 28.4 8.3 9.4 12.1 15.7 12.6 16.5 4.2 8.8 29.3 3.0 25.4 18.3 1.2 11.5 13.3 18.1 16.2 52.2 4.8 20.2 11.5 22.2 10.2 5.7 26.6 13.2 14.6 57.5 35.3 15.2 10.0 6.5 6.1 18.6 34.8 3.9 14.0 16.8 26.6 6.5 24.9 20.0 27.8 3.5 4.8 19.1 3.7 17.0 35.7 16.2 1.5 29.4 27.1 14.1 0.0 18.1 30.7 3.6 10.9 10.8 22.3 1.8 45.0 19.7 8.0 9.7 PRSS8 ENSG00000052344 "Serine protease 8" Q16651 16 31131433-31135727 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 245.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 403.5;Extravillous trophoblasts: 648.4;Paneth cells: 262.6;Proximal enterocytes: 358.0;Syncytiotrophoblasts: 450.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 243.7;CACO-2: 165.9;CAPAN-2: 111.9;hTCEpi: 157.8;OE19: 79.6;SK-BR-3: 186.3" "Region enriched" "Detected in single" 8 "hippocampal formation: 1.4" "Low region specificity" "Detected in single" HPA030436 Uncertain "Secreted - unknown location" NA NA 4400000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA030436: AB_10602291" "unprognostic (1.88e-1)" "unprognostic (2.97e-1)" "unprognostic (9.34e-2)" "unprognostic (4.08e-1)" "unprognostic (6.83e-2)" "unprognostic (5.07e-3)" "unprognostic (5.78e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-1)" "unprognostic (4.51e-2)" "unprognostic (8.74e-3)" "unprognostic (1.58e-1)" "prognostic favorable (2.05e-10)" "unprognostic (1.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (3.63e-3)" 0.8 0.4 0.3 15.0 0.4 0.2 25.5 2.1 0.6 31.1 6.7 129.4 155.7 9.9 113.0 136.2 15.4 47.7 0.4 0.6 0.2 90.6 28.0 54.1 0.3 0.3 0.2 0.6 139.4 56.0 8.4 51.0 0.4 49.0 72.6 0.0 245.4 8.5 0.3 115.3 151.8 3.5 0.1 0.2 156.2 0.5 0.2 15.4 50.8 0.0 11.8 4.9 56.0 0.2 63.4 0.2 0.1 0.2 0.0 0.0 243.7 0.0 0.0 0.0 0.0 165.9 111.9 0.0 1.3 0.0 0.0 73.5 0.1 69.7 0.0 0.3 0.4 0.1 0.3 6.5 0.0 0.0 0.3 0.0 157.8 0.0 2.4 0.0 0.0 0.1 1.9 0.1 0.0 68.1 0.6 1.4 20.5 79.6 0.1 0.5 0.0 1.2 7.5 13.1 0.9 0.7 0.0 186.3 0.1 18.8 42.8 0.8 0.0 0.1 1.9 0.6 0.4 0.3 0.5 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.1 0.6 0.6 0.2 0.3 0.2 0.4 0.1 0.2 0.2 0.4 99.3 60.1 0.0 1.0 37.9 82.7 108.9 76.2 0.5 74.4 39.2 0.3 62.9 107.4 42.3 0.0 168.8 0.8 403.5 29.4 192.4 0.0 35.2 11.4 2.6 9.6 2.7 0.1 224.4 648.4 3.5 82.6 109.5 7.0 0.0 0.0 18.2 22.8 0.0 0.2 132.1 87.5 0.3 2.7 0.0 0.6 1.9 3.6 0.0 4.2 0.3 0.0 0.0 0.0 240.7 262.6 0.0 0.1 66.0 358.0 28.6 21.2 0.1 0.0 0.1 4.7 0.0 0.2 81.9 54.0 450.7 2.2 0.0 150.8 91.0 PRUNE1 "DRES-17, H-PRUNE, HTCD37, PRUNE" ENSG00000143363 "Prune exopolyphosphatase 1" Q86TP1 1 151008420-151035713 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Mental retardation, Neurodegeneration, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.0;Breast glandular cells: 9.8;Breast myoepithelial cells: 8.9;Collecting duct cells: 11.0;Granulosa cells: 8.9;Proximal tubular cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 169.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028411 Uncertain Supported Cytosol NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA028411: AB_10603229" "unprognostic (6.24e-2)" "unprognostic (2.24e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (6.91e-2)" "unprognostic (2.02e-1)" "unprognostic (2.12e-3)" "unprognostic (7.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.92e-2)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (2.18e-1)" "unprognostic (3.21e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-1)" 10.1 9.5 12.2 7.7 12.1 4.4 14.9 16.1 15.1 15.0 12.4 14.8 12.5 14.8 15.6 12.4 16.0 9.2 33.4 12.4 12.6 18.8 14.3 10.8 10.8 12.0 12.5 17.2 10.7 20.9 12.6 7.1 11.9 12.2 14.5 10.8 13.2 14.4 29.4 11.5 12.0 14.1 11.9 11.2 11.2 18.3 12.8 16.2 32.5 21.4 12.6 13.7 11.9 13.5 11.0 11.6 20.2 19.3 24.3 6.6 10.9 5.1 11.2 18.7 16.4 14.1 13.0 22.2 21.7 6.9 5.5 15.5 19.9 13.4 14.6 24.5 22.6 26.6 11.8 20.4 13.5 17.5 13.0 8.4 24.7 10.2 9.5 15.4 9.2 29.4 21.1 18.3 8.9 26.2 27.2 14.1 18.7 39.7 15.0 24.2 12.8 21.5 13.4 14.9 28.7 23.5 17.5 23.5 16.1 28.3 32.6 25.7 6.3 6.6 7.8 7.5 8.1 44.1 40.0 169.1 6.5 13.0 16.9 19.1 8.1 17.8 16.4 7.8 19.8 14.4 18.1 18.6 11.9 15.4 21.7 17.5 18.6 18.8 12.2 6.4 18.5 22.3 12.2 12.1 16.1 15.1 12.4 12.6 12.0 12.5 11.9 11.9 12.8 13.5 4.5 6.4 13.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 9.8 8.9 0.0 0.0 3.1 11.0 0.0 4.1 3.2 0.0 0.0 6.0 0.0 4.3 7.8 2.1 0.0 0.0 0.0 5.7 4.8 2.5 0.0 6.4 0.0 8.9 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 5.6 0.0 0.0 1.0 0.0 0.0 8.9 2.9 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 5.1 2.8 4.8 0.0 0.0 PRUNE2 "A214N16.3, bA214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367" ENSG00000106772 "Prune homolog 2 with BCH domain" Q8WUY3 9 76611376-76906114 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.6;intestine: 110.9" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 918.7" "Cancer enhanced" "Detected in many" "renal cancer: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 51.1;LHCN-M2: 83.2;RH-30: 71.5;RPTEC TERT1: 40.1" "Low region specificity" "Detected in all" "HPA022470, HPA031079" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Nucleoplasm, Nucleoli" "HPA022470: AB_1845832, HPA031079: AB_10603230" "unprognostic (1.21e-1)" "unprognostic (3.65e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (2.43e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-2)" "unprognostic (3.60e-1)" "unprognostic (8.69e-2)" "unprognostic (2.11e-2)" "unprognostic (9.79e-2)" "prognostic favorable (1.37e-6)" "unprognostic (7.75e-2)" "unprognostic (1.06e-1)" "unprognostic (3.25e-3)" "unprognostic (3.80e-4)" 11.3 23.2 26.9 11.9 82.9 2.9 5.2 49.5 54.7 16.6 0.0 110.9 7.1 50.6 18.5 34.0 29.4 16.4 8.9 26.9 48.4 15.4 1.9 5.1 2.8 90.0 52.8 4.7 4.3 4.0 30.9 4.0 76.4 47.6 18.5 39.0 14.6 64.8 16.7 5.4 27.7 55.3 31.7 4.4 37.1 4.9 53.1 0.9 2.6 56.8 2.5 69.2 14.4 120.6 0.0 0.0 1.5 0.0 51.1 25.8 0.2 1.8 3.6 6.6 14.7 0.4 0.0 0.3 3.9 4.5 13.6 0.0 0.1 0.0 18.0 0.4 2.9 6.3 3.7 0.0 8.5 0.1 0.3 28.7 0.1 26.7 0.7 15.1 14.4 0.4 0.0 20.8 83.2 0.1 4.6 1.8 4.0 0.0 0.0 0.5 71.5 0.3 40.1 0.0 17.4 0.0 0.0 0.3 4.9 2.8 0.1 0.7 11.9 14.2 0.7 34.9 1.2 22.2 3.2 0.0 11.5 0.3 0.0 0.3 0.5 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.4 0.3 0.2 0.1 0.0 0.2 26.9 82.9 49.5 54.7 26.9 48.4 90.0 52.8 76.4 31.7 53.1 120.6 0.4 0.0 1.1 27.7 0.0 2.3 0.4 0.5 0.0 47.5 1.2 3.4 11.1 0.0 1.0 11.0 0.0 0.0 1.6 3.5 1.9 0.0 12.6 37.7 4.7 3.7 54.3 0.0 152.4 0.5 0.2 2.9 3.1 34.7 0.0 0.1 21.8 0.2 3.2 15.2 65.4 36.4 4.1 3.1 3.1 30.0 0.9 2.3 5.4 13.1 1.7 9.9 2.1 134.7 918.7 0.4 8.8 1.5 0.1 5.1 9.9 20.3 17.0 6.5 0.0 27.2 9.6 4.3 4.2 0.0 1.4 0.0 0.7 0.5 5.2 0.6 PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Intermediate filaments,Cytosol" NA NA 250000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol "Intermediate filaments" "CAB010434: AB_640866, HPA002920: AB_1079708" "unprognostic (1.59e-3)" "unprognostic (4.12e-3)" "unprognostic (3.83e-1)" "unprognostic (3.00e-1)" "unprognostic (4.65e-2)" "unprognostic (1.50e-2)" "unprognostic (3.85e-3)" "unprognostic (2.35e-1)" "unprognostic (1.44e-1)" "unprognostic (2.06e-2)" "unprognostic (4.95e-2)" "unprognostic (7.37e-3)" "unprognostic (1.64e-2)" "unprognostic (1.42e-2)" "unprognostic (2.09e-1)" "unprognostic (5.07e-2)" "unprognostic (1.09e-1)" 28.2 38.6 49.4 26.2 52.3 28.7 35.1 54.5 68.3 34.3 47.4 32.7 25.3 36.4 48.3 34.5 44.9 25.8 26.0 49.9 58.9 34.6 33.4 28.6 34.8 55.4 58.6 31.7 18.6 41.4 33.1 40.4 61.4 31.6 33.2 44.6 26.2 30.4 24.8 26.8 27.0 36.2 56.4 27.1 27.8 27.5 57.5 41.9 38.1 23.9 39.1 33.4 27.7 59.4 101.3 100.5 68.9 62.6 102.6 77.3 61.8 81.6 69.2 73.9 64.0 60.7 64.4 86.0 119.7 80.2 107.6 54.0 109.8 80.3 113.4 91.3 94.8 50.5 91.0 78.2 51.8 79.2 54.8 58.2 85.9 67.2 82.2 73.2 186.4 83.2 99.9 114.3 94.0 133.0 75.3 70.9 124.1 96.9 138.3 74.2 97.5 92.7 80.7 64.8 44.2 42.1 124.8 52.4 86.0 87.4 56.5 66.9 130.5 58.1 33.1 98.3 61.4 88.5 128.5 90.5 80.4 109.2 69.7 83.6 46.8 72.3 45.9 58.1 49.0 47.9 45.8 49.2 52.2 48.0 45.6 51.4 22.0 58.3 71.4 53.0 57.8 69.9 49.4 52.3 54.5 68.3 49.9 58.9 55.4 58.6 61.4 56.4 57.5 59.4 14.2 19.2 19.8 3.3 23.4 22.6 25.9 31.8 23.9 15.1 20.4 20.6 11.2 8.6 35.4 11.0 2.1 28.3 12.8 16.5 31.3 19.9 4.1 38.3 26.9 22.8 14.4 35.7 3.4 18.7 35.3 22.6 11.7 21.6 34.1 17.9 22.1 25.6 31.3 13.5 4.5 16.8 16.2 29.5 19.0 4.4 25.7 20.2 17.8 0.0 26.1 18.3 20.6 5.5 9.6 24.5 14.1 21.1 34.7 26.6 14.9 34.8 69.9 7.7 0.0 13.8 32.1 46.2 40.3 32.4 29.1 25.0 20.2 24.6 19.2 33.7 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 41.9" HPA001125 Approved Approved Vesicles NA NA 36000 "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA001125: AB_2666207" "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favorable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 6.9 12.2 10.4 2.8 11.5 0.9 9.1 11.1 12.1 4.8 11.6 7.2 12.1 4.6 17.2 5.0 12.0 5.2 27.1 9.9 11.7 18.9 19.1 5.6 3.1 11.8 11.9 7.4 5.3 10.6 7.6 2.4 12.1 9.1 5.7 10.7 6.7 5.4 32.8 6.9 8.9 2.6 11.3 3.4 6.2 6.2 10.6 3.0 12.6 32.1 2.6 4.2 4.1 13.9 8.9 11.9 9.6 4.7 7.6 16.3 7.6 3.0 4.1 3.6 5.6 6.8 21.2 0.9 6.8 3.0 8.4 8.8 8.7 6.5 6.6 6.7 4.1 6.2 5.5 3.0 3.8 2.3 2.2 7.7 15.1 5.5 4.4 7.8 1.8 6.1 8.3 1.8 8.2 12.7 6.2 5.9 10.7 11.9 11.6 7.6 3.7 1.5 19.7 8.6 12.7 11.0 7.7 8.1 9.8 9.1 41.9 3.7 2.7 5.3 10.0 3.9 6.6 10.2 4.7 2.8 8.3 5.5 7.2 6.7 1.1 0.9 0.6 0.4 0.6 1.0 1.1 0.5 1.3 1.0 1.8 1.5 0.8 1.3 1.2 1.5 1.1 1.0 10.4 11.5 11.1 12.1 9.9 11.7 11.8 11.9 12.1 11.3 10.6 13.9 4.5 19.2 13.0 10.7 2.9 6.8 12.8 16.7 6.2 8.9 8.4 5.5 43.2 8.6 12.9 18.4 14.6 6.3 2.0 8.6 25.4 11.7 2.4 21.5 5.8 5.2 4.8 4.2 8.0 8.7 2.5 6.1 5.1 7.3 3.8 9.3 3.3 14.3 7.4 33.7 10.3 10.0 10.2 5.5 3.1 2.0 7.2 4.3 8.8 5.6 4.0 22.3 6.2 7.1 20.4 8.7 11.1 6.8 2.9 7.2 24.8 18.4 31.6 20.8 6.6 9.9 6.1 42.1 18.8 3.5 6.7 4.0 2.9 17.3 11.7 7.7 PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 235.1;Late spermatids: 640.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA043932: AB_2678738, HPA060060: " "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (3.29e-2)" "unprognostic (2.77e-2)" "unprognostic (1.93e-3)" "unprognostic (6.76e-2)" "unprognostic (1.72e-1)" "unprognostic (2.68e-3)" "unprognostic (1.21e-1)" "unprognostic (5.39e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 38.8 56.5 15.0 5.3 16.1 9.0 37.4 15.8 17.4 31.1 16.6 31.0 7.6 32.8 7.8 34.8 29.5 4.2 27.7 14.4 16.5 37.6 40.6 36.5 6.1 15.6 16.3 28.0 44.7 9.6 41.9 6.7 15.8 32.7 3.9 4.2 37.1 5.9 41.0 28.1 23.4 4.7 16.0 28.9 39.2 105.4 17.0 4.3 30.6 5.8 4.9 27.5 28.1 16.0 34.5 19.4 2.3 17.8 17.5 11.4 7.0 20.1 17.1 19.4 16.8 27.9 17.6 27.9 22.1 14.7 16.8 30.6 16.9 20.4 16.6 31.4 57.3 12.9 43.8 43.4 25.7 25.2 17.1 12.7 21.9 8.8 24.0 11.2 13.7 26.2 32.6 19.5 14.2 65.4 21.4 41.0 18.8 3.9 37.7 38.6 16.7 22.3 22.5 23.3 15.5 21.4 33.8 11.1 23.2 7.2 53.1 32.7 16.6 13.6 23.3 28.6 33.1 27.1 22.6 18.6 13.6 23.3 10.0 11.2 38.0 38.2 24.8 36.8 23.0 33.7 22.7 26.2 44.9 30.3 22.3 21.0 3.1 26.1 34.6 64.6 28.5 28.8 15.0 16.1 15.8 17.4 14.4 16.5 15.6 16.3 15.8 16.0 17.0 16.0 26.8 22.4 35.0 14.4 31.8 17.8 15.8 58.5 34.1 14.4 64.9 78.4 5.8 45.8 38.6 40.5 4.2 72.2 34.7 19.9 72.4 95.3 235.1 48.0 23.9 24.6 31.3 30.1 8.2 85.8 66.3 23.9 28.1 25.6 17.1 16.5 29.6 39.8 62.4 5.0 10.8 45.7 48.8 32.6 21.2 640.8 46.6 45.6 46.2 6.5 56.2 74.9 41.2 9.5 14.6 106.2 38.8 46.6 61.0 26.0 37.9 72.8 57.2 15.7 19.7 17.3 28.1 179.8 28.6 55.0 17.3 76.8 25.9 21.3 62.7 22.0 PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 124.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 223.1;Astrocytes: 165.2;Oligodendrocytes: 200.2;Rod photoreceptor cells: 179.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 117.6;RT4: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002213, HPA063119" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB002213: AB_564089, HPA063119: " "unprognostic (5.36e-2)" "unprognostic (4.46e-1)" "unprognostic (1.11e-1)" "unprognostic (2.54e-3)" "unprognostic (4.02e-1)" "unprognostic (9.03e-3)" "unprognostic (4.43e-2)" "unprognostic (4.38e-2)" "unprognostic (2.46e-1)" "unprognostic (7.05e-2)" "unprognostic (3.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-3)" "unprognostic (3.95e-3)" "unprognostic (2.26e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-2)" 14.0 6.7 9.9 3.0 16.6 0.3 11.7 8.1 10.8 18.8 22.4 5.2 0.8 13.1 25.5 22.2 13.0 7.7 6.1 14.2 10.6 26.6 1.4 22.9 5.2 16.7 13.1 28.7 4.9 17.5 16.8 3.3 10.5 11.0 2.4 124.3 6.6 10.6 1.0 55.9 2.6 7.9 8.2 4.0 4.1 15.8 13.8 7.6 20.8 5.0 11.5 20.7 22.7 20.4 13.8 6.8 117.6 11.5 48.2 41.9 0.0 25.0 51.0 9.4 11.7 0.1 6.8 0.0 5.3 28.0 3.3 44.4 20.6 37.9 18.0 0.3 15.1 11.4 14.6 0.0 5.9 20.5 0.1 27.2 11.8 6.8 22.4 19.7 0.0 0.0 0.0 19.2 0.0 6.2 1.8 7.4 26.5 0.0 5.1 4.1 0.0 0.0 35.6 57.2 6.8 9.8 7.4 16.4 13.3 18.8 9.6 0.7 0.0 9.1 6.9 0.2 3.3 19.8 0.0 0.0 9.5 0.0 4.0 0.0 0.1 0.0 0.1 1.3 0.9 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 9.9 16.6 8.1 10.8 14.2 10.6 16.7 13.1 10.5 8.2 13.8 20.4 5.3 48.1 223.1 165.2 0.6 109.4 25.6 26.3 79.1 11.6 11.2 8.9 1.8 11.5 52.0 47.8 91.8 0.2 0.3 0.1 3.9 5.0 23.2 16.9 49.4 3.7 4.8 0.8 67.0 3.7 0.1 28.8 4.1 7.7 5.1 7.5 3.6 0.1 0.3 1.7 39.3 1.1 8.2 1.4 10.6 20.8 45.7 4.5 19.6 51.5 0.5 20.3 0.0 75.4 200.2 6.2 2.7 32.7 3.0 16.0 0.1 10.9 27.3 179.0 13.1 10.1 20.8 25.4 20.5 97.8 99.4 0.3 6.6 14.0 0.7 52.5 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 234.3;pituitary gland: 182.3" "Group enriched" "Detected in some" 9 "Bipolar cells: 59.0;Cone photoreceptor cells: 60.5;Enteroendocrine cells: 47.1;Excitatory neurons: 44.6;Horizontal cells: 97.6;Inhibitory neurons: 48.1;Rod photoreceptor cells: 38.4" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-2 OS: 66.4;U-87 MG: 249.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" NA NA 38000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "HPA007152: AB_2667759, HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavorable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 0.7 25.2 91.6 4.8 98.3 0.6 0.2 12.2 139.0 0.2 0.0 5.3 1.6 0.3 0.0 0.3 0.1 0.3 0.3 116.6 234.3 0.3 0.2 0.2 0.1 62.4 85.5 0.2 36.3 0.0 182.3 0.2 138.1 0.4 0.8 21.4 0.1 0.0 0.1 0.9 2.0 1.6 22.2 0.1 6.0 0.7 98.9 0.0 0.4 0.0 0.0 0.9 0.9 70.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 2.5 0.0 0.8 0.0 0.1 0.0 0.0 1.2 4.6 6.8 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.8 1.9 0.0 0.6 8.4 0.0 20.8 0.0 0.2 0.0 0.0 0.4 0.5 1.5 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 10.8 0.0 0.0 0.0 9.0 0.0 0.1 0.0 0.1 66.4 0.0 0.2 0.1 0.3 1.1 249.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 91.6 98.3 12.2 139.0 116.6 234.3 62.4 85.5 138.1 22.2 98.9 70.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.1 0.0 59.0 0.1 0.1 2.0 0.0 0.0 0.0 60.5 0.0 0.1 0.1 1.9 0.1 0.3 0.1 0.2 0.7 47.1 2.7 44.6 0.0 0.3 1.9 2.6 0.0 0.0 0.0 0.0 0.3 0.1 97.6 48.1 0.7 2.0 0.0 0.4 0.8 0.3 1.8 1.8 4.7 0.0 6.0 0.0 1.5 4.0 2.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 38.4 0.0 0.1 1.9 4.2 2.7 0.0 0.1 0.0 0.1 0.0 0.1 0.2 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789728-24793391 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 10.6 26.0 11.7 4.3 11.8 16.1 11.0 12.2 17.5 8.7 13.7 12.8 10.6 7.2 3.5 17.6 6.4 4.2 16.4 12.5 12.6 14.9 14.9 10.2 8.4 12.4 11.9 10.2 13.7 3.6 10.8 6.4 12.6 10.6 5.8 3.0 15.1 4.0 23.9 14.8 11.9 3.3 12.5 11.2 12.3 9.1 12.8 7.1 14.5 8.5 6.2 9.4 10.3 13.0 18.2 40.2 12.7 5.5 6.9 15.2 22.1 12.2 11.3 15.4 9.9 39.7 15.9 14.2 5.2 12.7 10.3 11.7 10.4 11.1 5.1 20.1 70.0 25.7 18.2 43.2 14.2 21.8 23.5 14.6 8.9 7.1 7.9 12.3 14.4 12.8 26.4 11.2 11.4 36.6 17.7 39.0 26.8 10.6 23.7 14.9 38.9 23.9 18.1 31.2 19.9 30.9 13.6 18.1 16.4 5.9 17.7 15.9 24.2 13.6 21.4 6.7 11.2 8.7 28.1 15.4 12.4 13.3 9.3 34.8 90.6 20.7 52.6 66.9 26.8 96.4 51.4 46.2 144.5 81.2 46.6 54.8 10.4 52.8 50.1 149.0 84.4 97.0 11.7 11.8 12.2 17.5 12.5 12.6 12.4 11.9 12.6 12.5 12.8 13.0 27.8 51.3 61.5 1.0 65.0 119.8 79.4 123.3 72.3 10.5 171.4 239.4 81.0 60.1 83.8 66.2 6.2 200.0 87.9 127.0 115.4 91.0 130.9 53.5 37.5 46.9 88.1 68.1 1.9 142.0 153.7 57.4 50.4 48.8 41.2 121.1 62.4 101.5 134.5 1.7 2.2 158.2 79.3 112.5 154.3 157.1 47.2 79.9 67.6 3.7 154.6 78.7 65.9 1.0 2.3 124.2 128.8 39.9 46.6 74.3 120.9 199.2 107.1 12.2 72.3 34.5 56.0 135.6 78.6 133.6 141.8 167.7 52.5 110.4 162.2 125.3 PWWP3B "FLJ33516, MUM1L1" ENSG00000157502 "PWWP domain containing 3B" Q5H9M0 X 106168305-106208956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "ovary: 189.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12.2;Cytotrophoblasts: 1.9;Endothelial cells: 1.7;Fibroblasts: 4.0;Syncytiotrophoblasts: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.9;HHSteC: 1.6;HSkMC: 2.9;LHCN-M2: 5.5;NTERA-2: 2.1;SuSa: 1.5;T-47d: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000168, HPA020464" Enhanced NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA000168: AB_1079431, HPA020464: AB_1854209" "unprognostic (2.79e-1)" "unprognostic (1.08e-2)" "unprognostic (3.83e-2)" "unprognostic (6.08e-2)" "unprognostic (5.06e-2)" "unprognostic (4.12e-6)" "unprognostic (3.48e-2)" "unprognostic (1.31e-1)" "unprognostic (3.86e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (8.43e-3)" "unprognostic (2.11e-5)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (2.53e-2)" 3.5 3.7 4.5 0.0 3.8 0.0 1.0 0.1 7.4 13.7 0.2 0.1 0.0 15.8 9.3 0.3 13.5 1.2 4.3 4.5 12.2 1.4 1.5 0.5 0.0 2.6 8.1 189.9 28.1 0.7 6.1 0.5 5.5 2.4 0.1 0.1 0.2 3.5 10.9 0.2 0.1 3.1 0.5 0.0 1.2 18.0 9.1 0.0 10.3 9.2 0.0 0.3 2.2 3.1 0.0 0.0 2.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.6 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 1.5 1.9 0.0 0.0 0.2 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 3.8 0.1 7.4 4.5 12.2 2.6 8.1 5.5 0.5 9.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 732.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 159.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 19.9 16.7 71.6 31.5 161.3 73.1 15.8 112.3 109.2 46.7 20.4 23.3 10.6 23.5 8.4 11.3 17.5 15.5 17.8 84.1 115.0 18.2 11.6 20.6 43.0 158.2 131.3 18.3 15.7 21.2 13.4 29.7 154.1 12.8 10.5 35.6 14.8 11.7 18.8 14.3 19.3 18.7 82.1 25.2 16.3 12.4 119.0 13.7 63.1 14.3 44.9 19.5 30.2 320.5 13.7 6.9 6.8 12.0 79.7 70.0 17.8 22.6 42.5 19.7 27.3 4.0 3.1 74.7 5.1 33.6 28.4 4.2 18.7 13.2 21.8 18.5 12.5 13.1 11.3 5.8 87.5 112.8 22.5 57.4 31.6 24.6 42.0 72.5 17.8 49.1 15.7 26.1 35.7 5.3 26.2 122.2 7.8 4.1 19.7 40.7 9.4 13.4 12.6 8.0 6.0 4.0 14.2 11.0 19.0 10.7 34.8 122.9 17.9 24.9 11.0 48.5 23.9 19.4 21.6 73.7 36.2 159.3 10.7 39.5 44.6 69.1 23.8 37.2 20.7 62.6 17.1 20.3 41.8 69.6 15.3 17.5 73.5 21.6 57.1 32.1 21.1 32.0 71.6 161.3 112.3 109.2 84.1 115.0 158.2 131.3 154.1 82.1 119.0 320.5 20.1 9.6 6.3 28.4 59.8 14.1 5.8 5.6 7.4 31.0 5.9 7.1 13.1 7.2 6.0 23.9 20.9 19.7 31.7 8.3 33.2 7.1 69.7 9.1 33.0 14.2 7.8 19.3 33.8 5.7 6.8 41.5 6.1 16.0 19.7 15.2 16.4 7.5 13.6 20.2 53.7 5.0 2.0 24.5 31.1 38.3 30.7 25.2 17.8 30.0 28.6 32.7 30.9 79.4 732.6 3.0 5.5 25.2 17.6 6.0 8.7 12.2 6.4 22.2 19.7 18.7 18.2 16.8 21.9 10.1 13.1 35.2 16.9 18.3 5.0 3.9 PXMP4 PMP24 ENSG00000101417 "Peroxisomal membrane protein 4" Q9Y6I8 20 33702758-33720319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 73.6;Late spermatids: 44.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 42.3;SK-BR-3: 75.8;T-47d: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050077 Approved Approved "Nucleoli fibrillar center,Peroxisomes" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Peroxisomes "Nucleoli fibrillar center" "HPA050077: AB_2681006" "unprognostic (3.41e-2)" "unprognostic (1.11e-1)" "unprognostic (2.59e-1)" "unprognostic (1.75e-1)" "unprognostic (5.08e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-1)" "prognostic favorable (3.88e-4)" "unprognostic (3.53e-1)" "unprognostic (4.47e-2)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "prognostic favorable (4.03e-10)" "unprognostic (3.84e-2)" "unprognostic (2.20e-1)" "unprognostic (6.08e-2)" "unprognostic (2.20e-1)" 4.1 11.2 5.1 3.0 5.2 3.2 11.9 3.8 5.6 5.6 4.3 6.2 8.2 4.1 5.1 6.3 6.0 3.3 6.4 5.0 4.0 4.9 8.9 13.9 3.6 4.6 4.5 6.8 6.8 14.7 3.5 3.2 4.1 8.7 5.7 4.4 15.2 6.4 8.0 11.1 7.4 5.1 4.2 4.6 6.8 2.5 5.3 3.5 11.5 6.9 3.9 5.4 5.8 6.5 2.8 12.1 3.3 11.9 5.7 8.3 8.5 8.7 4.7 6.6 2.9 42.3 13.2 0.1 16.2 7.3 16.1 12.5 9.0 10.1 4.7 3.7 3.4 14.0 9.7 0.1 5.3 0.7 10.3 6.4 10.8 9.0 3.0 3.3 4.3 4.4 7.9 8.6 4.7 26.4 12.9 9.8 0.3 21.7 0.0 6.8 16.3 1.7 4.2 9.0 10.7 5.4 24.2 75.8 7.9 1.9 64.0 4.7 8.2 4.7 5.4 11.9 8.2 5.5 13.2 0.2 9.0 4.6 8.1 2.2 11.1 17.5 10.8 22.2 11.3 7.6 10.9 10.9 8.8 9.9 8.3 11.2 2.9 9.1 34.2 5.3 8.5 8.6 5.1 5.2 3.8 5.6 5.0 4.0 4.6 4.5 4.1 4.2 5.3 6.5 5.2 19.2 73.6 7.2 5.5 1.7 4.3 9.4 4.0 11.1 16.8 12.3 12.6 7.2 17.8 18.4 14.6 12.9 3.5 14.2 9.8 8.2 28.7 6.3 6.1 7.6 4.2 9.9 6.4 9.9 24.3 8.5 6.6 5.7 3.8 6.7 8.9 36.0 15.1 5.0 5.7 10.8 6.1 7.5 1.6 44.0 10.5 6.2 3.6 6.5 7.5 13.6 9.2 9.0 10.8 8.5 10.3 11.3 7.0 4.5 23.0 11.2 7.8 11.4 6.6 8.8 7.8 4.6 9.8 9.5 2.4 4.4 5.8 16.9 13.0 4.0 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Enhanced "Vesicles,Centriolar satellite" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Centriolar satellite" "CAB013097: AB_2533987, HPA051697: AB_2732569, HPA060686: AB_2684342" "unprognostic (4.15e-2)" "unprognostic (5.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (3.17e-2)" "unprognostic (7.12e-2)" "unprognostic (8.60e-2)" "unprognostic (4.83e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.29e-2)" "prognostic favorable (1.46e-5)" "unprognostic (9.93e-2)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" 140.0 231.6 79.7 123.9 86.4 126.0 150.1 83.4 105.0 159.3 78.5 223.8 139.8 117.4 130.9 480.0 146.1 185.1 156.3 86.1 97.4 162.9 124.1 148.1 141.2 87.0 83.0 104.9 107.6 192.5 106.8 214.4 101.3 150.3 224.2 99.0 195.1 126.2 119.6 288.5 158.9 149.2 87.2 183.9 216.2 201.8 86.0 143.6 155.3 109.6 246.0 269.8 232.2 86.7 285.2 330.3 330.1 240.8 294.7 275.0 431.1 297.0 300.4 264.4 313.0 305.8 497.4 370.7 295.8 342.6 262.3 429.0 525.0 393.2 248.2 243.7 314.9 445.3 219.9 274.1 224.7 211.5 254.0 282.8 438.1 260.2 214.7 281.7 595.2 197.8 364.5 214.3 378.1 283.7 209.9 167.3 275.9 1057.4 185.9 176.3 250.5 346.3 716.1 734.7 237.4 251.9 214.0 335.6 286.5 387.8 445.0 243.0 453.7 208.4 296.4 203.1 267.8 112.2 289.5 288.8 193.7 353.5 228.8 183.5 154.8 235.2 56.7 133.9 58.8 78.8 85.3 68.6 137.1 64.1 78.9 63.6 232.8 71.3 154.6 87.6 109.5 340.2 79.7 86.4 83.4 105.0 86.1 97.4 87.0 83.0 101.3 87.2 86.0 86.7 155.7 57.7 57.8 15.3 90.2 192.2 180.2 375.2 134.3 42.3 107.5 69.6 89.5 105.8 245.4 187.6 33.3 326.4 76.0 313.4 346.3 360.6 413.1 119.3 72.7 260.7 206.2 91.1 31.3 337.0 340.4 96.9 149.9 194.5 74.9 75.9 235.2 88.4 239.2 57.2 27.7 227.4 244.1 114.8 214.2 80.9 97.3 148.1 186.7 42.2 217.8 137.9 65.9 25.6 21.9 391.1 277.0 86.5 72.1 187.6 205.8 271.5 240.0 36.1 46.0 45.2 161.5 407.5 95.3 225.5 284.4 969.3 96.6 97.6 209.2 360.8 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAB2A RAB2 ENSG00000104388 "RAB2A, member RAS oncogene family" P61019 8 60516936-60623644 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018781 Approved NA NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "CAB018781: AB_654960" "prognostic unfavorable (8.22e-4)" "unprognostic (1.84e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (1.37e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-1)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (5.10e-1)" "unprognostic (7.57e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" 67.0 52.0 42.6 36.5 49.0 48.7 49.1 38.4 63.0 48.5 30.2 54.4 49.1 45.5 48.9 83.2 32.1 37.7 70.2 48.5 52.3 63.3 70.3 40.9 26.4 41.4 41.7 35.0 43.2 68.6 39.0 51.2 44.4 55.0 48.3 41.2 54.5 37.7 115.8 42.1 53.0 40.0 42.2 33.5 60.6 27.4 44.9 31.2 62.4 69.1 27.8 48.4 59.9 42.2 121.6 68.6 46.2 40.4 152.8 105.9 65.7 101.5 72.5 50.3 58.5 29.5 92.0 39.0 40.2 129.4 83.7 70.8 55.4 64.9 69.2 59.8 45.9 56.3 30.1 40.8 112.9 17.3 48.8 113.9 86.6 57.0 68.6 101.1 62.9 32.6 36.0 51.0 80.1 40.4 75.1 29.3 42.6 176.5 30.6 45.6 20.2 33.9 94.2 55.0 31.6 63.2 43.8 84.2 92.0 60.3 84.1 40.3 104.2 66.9 64.3 100.4 63.0 64.7 49.4 43.6 97.3 37.7 82.7 230.0 164.4 241.2 88.0 149.3 81.5 112.3 90.0 101.2 147.7 108.9 92.2 100.1 310.9 130.2 152.0 97.1 117.7 129.3 42.6 49.0 38.4 63.0 48.5 52.3 41.4 41.7 44.4 42.2 44.9 42.2 167.5 157.0 129.0 67.3 99.3 214.4 197.0 267.0 135.5 102.2 152.6 148.2 182.0 117.2 190.7 165.5 16.7 214.4 112.2 198.6 426.5 266.4 404.2 133.2 200.4 163.8 178.6 56.0 103.7 278.1 365.2 194.9 107.6 197.1 92.5 103.6 121.3 261.9 204.2 124.5 89.6 332.0 266.5 100.2 146.1 111.6 175.2 129.4 279.3 89.0 159.3 153.6 129.8 133.7 124.9 324.4 168.6 165.5 143.8 315.2 200.2 366.4 142.1 60.8 170.9 149.3 236.2 219.7 106.2 210.6 241.5 467.8 102.8 162.7 169.9 335.6 RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145326-23164350 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 41.2;Late spermatids: 24.5;Respiratory ciliated cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 11.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 11.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.5;U-266/84: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA059631: " "unprognostic (2.74e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (6.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-3)" "unprognostic (5.56e-3)" "prognostic favorable (4.55e-4)" "unprognostic (7.08e-2)" "unprognostic (7.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.08e-1)" 2.0 5.1 8.8 1.3 8.7 0.7 2.6 3.8 8.4 5.1 21.7 3.2 0.7 4.8 4.4 2.1 32.8 5.3 1.4 9.9 9.1 9.1 0.4 4.8 1.1 9.4 11.2 6.2 3.4 5.6 17.1 2.9 6.9 3.9 1.1 2.0 3.3 6.6 0.6 1.8 1.2 3.8 7.9 1.6 2.1 6.7 10.4 0.3 17.6 0.4 1.3 2.5 2.1 5.1 8.1 9.4 7.1 10.7 1.6 3.4 2.8 4.5 9.1 9.8 3.7 0.6 0.0 0.0 4.8 6.0 5.4 10.0 0.3 5.2 3.1 0.0 4.3 0.1 0.4 0.9 4.1 0.0 1.2 4.3 1.9 9.1 1.8 6.4 1.4 0.0 0.4 8.1 0.4 6.4 0.1 0.1 0.9 5.3 2.5 0.0 0.0 25.5 12.7 1.5 17.3 7.5 0.4 3.9 2.2 0.5 0.0 0.9 0.8 1.3 2.9 3.4 6.5 17.3 26.2 0.1 8.8 0.0 5.8 0.3 0.6 0.0 0.5 0.2 0.3 0.8 0.1 0.2 0.2 0.2 0.3 0.3 11.0 1.6 0.3 0.0 0.0 0.3 8.8 8.7 3.8 8.4 9.9 9.1 9.4 11.2 6.9 7.9 10.4 5.1 0.6 0.0 3.2 3.6 1.4 0.5 0.8 4.2 0.0 0.7 1.8 2.8 0.8 4.3 7.0 1.8 6.2 6.0 0.3 0.0 5.9 3.5 10.6 41.2 2.9 0.7 6.7 0.0 2.9 0.2 0.4 2.0 1.5 2.6 1.3 2.4 1.1 0.1 0.4 1.7 1.7 0.7 6.1 0.8 0.3 24.5 3.4 0.3 1.8 1.0 0.5 3.6 1.0 1.5 1.0 0.2 0.2 3.0 0.3 0.4 0.0 9.6 69.6 0.7 0.0 1.0 2.0 3.6 1.6 0.5 0.1 2.9 0.4 4.5 0.3 0.4 RABL3 MGC23920 ENSG00000144840 "RAB, member of RAS oncogene family like 3" Q5HYI8 3 120684938-120742993 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035150, HPA035151, HPA069861" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "HPA035150: AB_2674493, HPA035151: AB_10601154, HPA069861: " "unprognostic (1.69e-2)" "unprognostic (5.10e-2)" "unprognostic (8.32e-2)" "unprognostic (3.96e-2)" "unprognostic (1.88e-1)" "unprognostic (7.22e-2)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (7.19e-2)" "unprognostic (2.94e-1)" "unprognostic (2.11e-3)" "unprognostic (2.78e-1)" "prognostic favorable (2.79e-5)" "unprognostic (2.33e-1)" "unprognostic (6.15e-2)" "unprognostic (8.44e-3)" "unprognostic (3.65e-1)" 10.8 16.1 2.3 5.6 2.5 5.3 8.8 2.6 4.1 7.0 2.6 8.1 5.5 7.0 2.7 7.9 5.9 5.7 7.3 2.1 3.1 9.8 9.7 5.6 5.9 3.0 2.8 9.2 6.4 11.8 6.3 6.9 2.9 6.9 8.6 5.8 6.9 6.5 13.8 6.3 6.0 6.2 2.7 5.6 7.1 4.2 2.4 6.4 12.3 11.9 7.3 7.3 7.9 3.7 20.6 17.8 12.6 3.9 11.7 17.0 11.4 18.8 13.8 10.0 8.3 12.6 6.5 17.3 8.5 15.4 17.6 7.1 14.0 9.2 18.3 14.8 5.9 16.0 12.9 15.7 8.1 31.2 9.1 8.4 11.2 8.9 10.7 11.6 15.1 9.4 14.2 9.7 12.8 20.8 18.2 3.0 6.4 19.9 8.6 7.7 17.4 6.6 9.6 10.0 5.8 4.5 9.2 5.5 5.4 4.8 10.5 9.8 22.1 6.5 7.5 4.8 17.1 5.4 7.9 13.6 16.7 25.4 8.4 3.7 3.6 2.6 4.6 5.6 3.6 3.2 4.5 5.1 6.5 2.6 3.8 4.4 3.7 5.6 3.1 3.4 5.3 3.4 2.3 2.5 2.6 4.1 2.1 3.1 3.0 2.8 2.9 2.7 2.4 3.7 17.6 9.6 11.7 14.7 11.6 6.4 17.2 17.3 11.4 39.8 13.7 10.0 14.3 12.8 16.7 9.2 116.7 13.3 7.7 13.1 7.9 15.2 25.5 22.3 11.9 12.8 5.4 10.7 11.7 16.2 18.0 13.8 9.7 14.2 8.2 10.4 8.2 18.1 14.7 8.4 10.2 12.7 16.2 10.6 7.2 9.8 5.9 12.0 10.6 2.8 11.4 19.2 9.2 7.5 17.1 14.6 15.8 6.0 11.3 12.2 9.6 26.4 15.7 20.0 0.0 16.5 10.4 26.9 8.5 10.5 11.1 22.0 10.0 16.6 12.1 15.4 RASEF "FLJ31614, RAB45" ENSG00000165105 "RAS and EF-hand domain containing" Q8IZ41 9 82979590-83063177 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 41.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 101.7;Gastric mucus-secreting cells: 356.8;Prostatic glandular cells: 106.4;Respiratory ciliated cells: 100.6;Urothelial cells: 107.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 53.2;RT4: 38.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021431, HPA078596" Approved Uncertain Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Microtubules "HPA021431: AB_1856087, HPA078596: " "unprognostic (1.22e-1)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (1.26e-1)" "unprognostic (2.59e-1)" "unprognostic (2.40e-2)" "unprognostic (9.91e-3)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (8.60e-2)" "unprognostic (1.66e-3)" "unprognostic (3.67e-1)" "unprognostic (1.41e-3)" "unprognostic (5.07e-2)" "unprognostic (6.05e-3)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" 1.1 1.6 16.2 2.8 15.4 3.6 17.6 21.2 21.9 2.9 18.0 15.2 6.3 2.7 10.2 7.1 6.3 12.6 1.1 13.9 9.2 5.3 2.4 8.2 1.5 10.0 6.3 1.5 23.1 5.3 3.9 3.4 9.8 15.2 15.2 5.1 15.3 3.8 1.9 3.8 8.6 1.1 1.0 1.5 41.0 4.0 9.8 3.4 25.9 0.0 3.5 13.8 2.3 24.7 14.0 15.5 1.8 1.5 0.3 0.5 5.6 1.0 0.2 1.6 3.9 8.7 16.9 2.3 13.7 0.4 11.0 16.3 0.3 0.4 1.9 1.4 17.3 1.9 11.9 2.2 0.2 1.7 1.6 0.3 6.7 7.6 0.2 2.1 0.1 2.4 2.5 16.8 0.2 27.2 2.3 1.8 10.5 53.2 6.1 2.5 4.8 6.0 18.0 38.5 5.6 8.3 2.8 26.8 1.1 6.7 22.9 2.0 2.6 2.6 14.6 2.1 1.7 11.3 10.1 1.4 5.8 1.0 3.0 6.5 2.0 1.9 3.7 1.4 3.5 3.9 3.5 2.9 1.1 5.3 3.8 3.3 9.8 3.6 1.6 3.8 2.9 0.7 16.2 15.4 21.2 21.9 13.9 9.2 10.0 6.3 9.8 1.0 9.8 24.7 0.7 76.9 101.7 0.3 1.1 0.8 5.4 7.9 4.0 1.1 61.3 21.1 0.6 42.9 59.7 9.2 4.2 5.5 0.5 61.8 7.9 35.4 0.6 39.7 7.9 4.5 3.6 0.8 1.0 37.4 10.3 5.7 356.8 88.2 22.1 0.4 0.7 1.7 0.8 0.0 0.6 85.7 48.8 0.0 0.4 2.1 0.3 4.2 1.8 4.7 1.6 0.1 0.0 0.0 0.2 46.2 40.0 0.0 1.5 106.4 10.4 8.3 100.6 1.3 0.0 0.7 2.8 0.5 4.8 28.2 0.9 7.5 3.1 1.2 35.7 107.7 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 442.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 136.2" "Group enriched" "Detected in many" 12 "dendritic cells: 34.4;granulocytes: 136.2;monocytes: 45.5" "Cell line enhanced" "Detected in many" "BEWO: 134.0;CAPAN-2: 63.5;OE19: 56.7;SK-BR-3: 58.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA006347: AB_2181208" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.49e-3)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-2)" "unprognostic (7.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.22e-1)" "unprognostic (9.42e-2)" "unprognostic (3.04e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.33e-16)" "unprognostic (1.62e-2)" "unprognostic (9.81e-2)" "unprognostic (1.72e-1)" "unprognostic (5.77e-2)" 9.3 49.7 2.2 20.3 1.9 9.6 24.7 1.8 3.0 15.3 44.9 61.0 68.4 3.5 23.1 42.2 17.7 17.9 1.3 2.8 2.3 67.6 34.5 21.0 8.2 6.0 3.2 2.2 25.9 27.8 3.2 20.1 4.9 33.2 50.5 0.4 59.4 13.4 0.5 9.0 64.1 4.7 4.1 14.7 64.6 6.7 5.7 4.4 49.5 1.1 11.4 22.6 15.5 6.8 31.9 47.8 0.0 1.8 0.2 0.0 134.0 0.8 1.6 0.1 0.6 28.3 63.5 0.2 23.0 1.2 3.8 14.2 0.9 11.8 0.3 0.2 7.6 0.0 3.1 7.9 0.6 0.3 0.3 0.8 6.0 0.1 0.1 1.8 0.0 0.0 1.8 7.0 0.1 18.1 0.2 1.1 13.5 56.7 2.4 0.2 0.0 34.7 46.8 41.6 1.6 0.3 17.3 58.4 0.3 14.8 23.9 9.0 0.0 0.5 1.9 0.3 1.0 23.5 37.7 4.1 5.0 3.9 0.2 0.5 45.5 0.5 0.2 33.1 0.3 5.9 0.2 0.1 34.4 5.4 0.4 0.1 136.2 0.5 26.2 14.1 0.2 16.9 2.2 1.9 1.8 3.0 2.8 2.3 6.0 3.2 4.9 4.1 5.7 6.8 1.1 80.1 116.6 0.7 21.2 58.9 75.2 42.9 95.0 0.1 145.7 63.5 1.9 75.8 92.2 112.2 0.0 99.6 16.3 442.8 64.6 90.6 1.3 132.6 9.5 6.0 121.9 2.5 2.5 115.4 84.3 7.7 174.8 143.7 7.0 8.7 23.6 140.4 92.6 1.7 1.9 234.2 59.0 138.8 92.8 2.6 2.5 119.9 37.4 82.4 80.6 0.3 1.0 2.5 0.8 108.0 228.1 1.2 40.1 164.7 218.1 143.6 118.3 0.1 0.0 1.4 5.1 2.6 10.4 178.1 75.4 262.6 4.8 16.9 203.8 295.4 RDH11 "ARSDR1, MDT1, SDR7C1" ENSG00000072042 "Retinol dehydrogenase 11" Q8TC12 14 67676800-67695793 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Cataract, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 582.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 241.8;Muller glia cells: 299.7;Prostatic glandular cells: 285.7" "Cancer enriched" "Detected in all" 13 "prostate cancer: 286.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB046011 Enhanced "Intracellular and membrane" NA NA 340000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "CAB046011: AB_11129613" "unprognostic (1.38e-1)" "unprognostic (6.86e-3)" "unprognostic (1.77e-1)" "prognostic favorable (2.62e-4)" "unprognostic (6.06e-2)" "prognostic unfavorable (2.89e-5)" "unprognostic (9.29e-2)" "unprognostic (1.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.58e-2)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "prognostic favorable (1.30e-7)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (4.74e-2)" 23.6 59.5 39.3 24.5 43.2 13.9 28.7 50.2 54.4 32.6 35.9 29.2 34.1 33.2 86.0 34.6 23.5 42.7 17.6 40.4 47.2 106.0 153.1 34.9 20.4 49.2 47.7 28.9 42.6 79.8 23.4 21.9 49.3 582.0 31.4 73.9 44.2 34.4 8.3 31.4 23.9 43.6 49.8 22.2 31.9 28.4 46.1 30.7 61.7 13.5 26.2 34.3 30.3 58.4 183.7 81.9 71.3 82.0 111.5 100.4 59.3 68.0 134.2 83.7 150.9 68.6 216.7 31.7 51.2 64.6 104.8 142.5 104.0 150.8 113.7 63.0 42.6 65.1 40.7 69.0 106.9 24.3 46.0 94.4 98.0 109.3 92.0 63.9 97.4 87.0 52.1 101.1 77.2 97.5 72.2 38.8 40.4 49.7 92.8 53.6 87.4 45.8 194.1 93.0 73.8 62.0 71.2 89.7 99.1 58.2 100.7 38.3 74.2 89.5 101.1 38.9 49.5 47.5 40.0 40.7 115.8 66.0 74.3 282.4 71.1 104.0 62.3 57.7 68.2 39.0 67.7 61.5 51.3 45.5 67.3 64.8 11.0 56.3 65.4 59.1 65.1 115.8 39.3 43.2 50.2 54.4 40.4 47.2 49.2 47.7 49.3 49.8 46.1 58.4 27.0 25.6 66.0 38.2 29.2 11.5 40.0 77.9 16.5 53.5 45.4 24.5 20.4 68.6 59.9 47.8 50.1 24.9 32.4 26.8 7.9 92.5 2.5 21.9 50.9 39.3 43.3 29.2 33.3 84.0 38.1 37.5 19.9 38.2 29.2 46.3 47.8 241.8 35.8 79.1 37.6 28.9 89.5 42.4 15.4 6.1 43.2 35.9 35.6 17.8 39.8 299.7 37.0 70.4 43.4 61.2 36.7 56.1 27.3 285.7 17.5 56.0 23.9 97.0 46.0 29.7 38.7 25.8 24.0 20.2 19.2 63.5 29.8 66.7 25.3 46.1 REEP5 "C5orf18, D5S346, DP1, POB16, TB2, Yip2e" ENSG00000129625 "Receptor accessory protein 5" Q00765 5 112876385-112922289 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003895, HPA069960" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA003895: AB_1845723, HPA069960: AB_2686221" "unprognostic (3.26e-3)" "unprognostic (2.60e-1)" "unprognostic (2.71e-1)" "prognostic favorable (5.23e-6)" "unprognostic (8.29e-2)" "unprognostic (1.44e-2)" "unprognostic (1.13e-1)" "unprognostic (8.41e-2)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (7.75e-2)" "unprognostic (5.90e-2)" "prognostic favorable (2.05e-5)" "unprognostic (2.88e-2)" "unprognostic (4.14e-2)" "unprognostic (1.83e-1)" "unprognostic (3.24e-2)" 76.9 105.4 97.1 50.5 100.2 27.3 130.6 92.7 120.7 87.1 76.8 66.6 56.8 58.4 120.0 52.1 64.7 60.8 133.2 107.3 110.5 148.0 124.3 80.4 48.2 112.2 104.8 72.2 123.0 140.7 41.5 66.6 115.2 98.9 58.1 81.5 147.7 84.2 114.3 59.1 58.1 55.0 96.4 54.3 70.2 28.3 120.0 32.1 239.4 99.6 56.7 73.2 49.1 98.3 101.7 90.9 29.7 72.5 136.0 115.9 104.7 102.2 92.6 96.4 103.4 74.9 138.1 42.5 179.6 105.1 112.5 107.5 66.8 138.9 88.5 190.6 116.4 42.8 56.3 63.5 126.8 36.9 77.4 81.3 136.0 82.2 78.0 94.5 113.7 38.7 26.0 84.5 121.3 100.0 15.7 60.7 43.4 73.5 75.3 22.4 84.3 116.6 229.1 108.4 56.9 43.1 148.5 244.6 99.8 75.5 287.3 58.9 142.4 83.4 32.0 126.5 126.4 97.6 126.2 33.8 142.6 65.4 47.8 224.4 222.9 234.3 140.1 249.5 149.4 175.7 112.7 133.9 189.0 149.2 52.5 94.6 253.0 112.7 316.2 133.6 177.9 236.4 97.1 100.2 92.7 120.7 107.3 110.5 112.2 104.8 115.2 96.4 120.0 98.3 141.2 166.7 102.3 30.0 131.1 93.0 177.7 291.6 89.4 83.5 225.3 188.1 217.3 145.8 213.7 195.0 89.6 296.0 138.4 77.0 82.2 275.1 231.5 111.8 97.0 130.5 118.0 34.9 78.6 414.1 352.8 182.3 65.7 141.6 108.9 76.0 118.2 197.0 267.1 87.5 95.0 127.5 256.3 135.0 159.9 42.0 116.2 168.8 206.3 36.5 188.6 97.2 101.0 44.7 71.5 316.5 141.1 133.9 271.6 225.3 134.1 146.1 170.6 80.0 111.7 92.6 253.0 162.8 63.9 118.1 101.6 489.8 123.7 100.3 104.5 214.8 RETN "ADSF, FIZZ3, RETN1" ENSG00000104918 Resistin Q9HD89 19 7669049-7670455 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Hormone "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 247.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 118.2;Kupffer cells: 47.0;Macrophages: 90.4;monocytes: 58.2" "Group enriched" "Detected in many" 4 "lung cancer: 2.6;pancreatic cancer: 4.8;thyroid cancer: 1.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "classical monocyte: 170.4;intermediate monocyte: 91.7;myeloid DC: 118.7;non-classical monocyte: 47.4" "Group enriched" "Detected in many" 11 "dendritic cells: 118.7;monocytes: 170.4" "Group enriched" "Detected in some" 11 "NB-4: 524.3;U-937: 243.2" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Secreted to blood" NA NA 5120000 1200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.61e-2)" "unprognostic (6.20e-3)" "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (5.19e-4)" "unprognostic (1.53e-4)" "unprognostic (7.34e-2)" "unprognostic (3.35e-2)" "unprognostic (9.30e-2)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (4.02e-1)" "unprognostic (7.16e-5)" "unprognostic (4.23e-2)" "unprognostic (2.26e-1)" "unprognostic (8.91e-2)" "unprognostic (1.20e-1)" 3.4 1.0 0.1 5.2 0.1 247.2 1.4 0.0 0.9 0.6 0.0 0.8 6.1 0.7 0.0 0.5 2.4 0.3 2.3 0.4 0.1 1.7 3.3 34.0 0.1 0.1 0.1 0.4 0.9 0.1 0.5 1.1 0.1 1.0 0.2 0.0 1.1 0.0 0.6 0.7 0.7 4.3 0.0 53.3 1.0 0.2 0.0 4.0 0.8 0.0 0.0 0.6 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.9 524.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 243.2 0.0 0.1 170.4 0.1 0.4 91.7 1.2 0.0 1.9 1.5 118.7 0.1 4.4 9.0 13.6 0.3 47.4 4.5 0.0 64.3 0.1 0.1 0.0 0.9 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 12.8 9.9 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 1.1 0.6 0.0 0.0 3.8 0.0 0.4 0.1 118.2 0.0 0.0 0.0 0.0 47.0 8.7 0.2 0.0 90.4 0.0 0.0 58.2 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 2.2 0.0 0.0 0.1 RHPN2 ENSG00000131941 "Rhophilin Rho GTPase binding protein 2" Q8IUC4 19 32978592-33064888 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.0;Endometrial ciliated cells: 90.2;Gastric mucus-secreting cells: 94.8;Glandular and luminal cells: 108.8;Muller glia cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 52.4;OE19: 50.7;RPTEC TERT1: 52.9;SK-BR-3: 54.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051749 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "HPA051749: AB_2681589" "unprognostic (1.18e-1)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (3.65e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.52e-2)" "unprognostic (2.08e-3)" "unprognostic (2.32e-1)" "unprognostic (5.07e-3)" "unprognostic (3.01e-3)" "unprognostic (1.26e-1)" "prognostic favorable (1.22e-8)" "unprognostic (3.74e-2)" "unprognostic (4.44e-2)" "unprognostic (5.81e-2)" "unprognostic (4.40e-2)" 3.0 0.8 5.5 4.4 5.9 0.0 12.7 5.8 6.6 8.4 7.8 23.6 21.7 5.4 2.4 1.2 15.0 13.6 1.5 5.2 5.8 14.5 19.6 4.1 1.3 6.3 6.9 1.7 12.4 16.9 4.8 8.2 6.1 27.1 19.0 20.2 19.4 2.2 0.3 10.5 17.8 1.8 5.1 0.9 35.2 0.7 7.2 1.9 5.4 0.9 2.6 11.5 1.1 6.4 28.6 52.4 4.9 8.6 1.0 0.1 24.5 6.6 5.0 10.0 10.5 45.9 28.6 0.0 41.1 3.7 8.8 13.5 15.9 5.8 12.4 13.2 9.7 3.2 5.9 17.9 6.6 0.0 4.1 1.2 11.5 8.4 4.7 7.6 1.3 1.2 7.2 0.0 3.0 24.4 0.1 2.9 10.5 50.7 8.4 0.0 6.0 5.6 52.9 14.0 11.0 5.8 11.2 54.5 13.4 13.9 15.2 1.4 0.7 0.1 12.7 3.6 11.2 6.3 4.6 2.1 1.6 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.9 5.8 6.6 5.2 5.8 6.3 6.9 6.1 5.1 7.2 6.4 0.3 22.4 1.1 20.2 3.9 1.3 6.3 6.2 7.4 1.9 30.4 15.4 0.9 17.2 14.7 12.9 12.5 18.2 2.1 61.0 3.9 31.0 0.4 90.2 11.1 1.1 4.8 0.0 1.3 13.1 6.8 6.4 94.8 108.8 1.3 0.2 3.3 13.0 1.9 0.0 1.4 22.2 18.3 3.0 0.0 0.3 2.1 1.6 1.8 4.7 0.0 76.8 0.0 9.5 1.6 33.8 52.6 1.2 6.1 23.5 11.7 19.8 51.9 10.1 0.0 0.6 3.7 0.0 1.4 3.8 1.8 3.4 1.1 0.0 23.3 36.1 RIC8B "FLJ10620, hSyn, RIC8" ENSG00000111785 "RIC8 guanine nucleotide exchange factor B" Q9NVN3 12 106774621-106889316 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.4;Inhibitory neurons: 93.9;Microglial cells: 58.1;Oligodendrocyte precursor cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039970, HPA042746" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "HPA039970: , HPA042746: AB_2678143" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (9.87e-3)" "unprognostic (5.43e-2)" "unprognostic (3.28e-2)" "unprognostic (8.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.60e-1)" "unprognostic (1.99e-2)" "unprognostic (3.83e-1)" "unprognostic (1.10e-3)" "unprognostic (5.13e-2)" "unprognostic (3.65e-3)" "unprognostic (2.21e-1)" "unprognostic (3.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" 5.5 5.3 7.7 3.2 26.1 1.3 4.9 7.9 9.7 5.5 6.6 6.4 3.1 7.0 4.3 3.1 6.3 5.6 8.7 6.8 8.7 7.2 5.8 3.7 2.5 6.6 11.5 5.8 6.2 11.5 7.8 3.7 6.5 4.5 3.9 12.6 3.5 8.2 7.3 2.7 4.1 6.4 5.4 4.7 4.1 4.4 9.3 6.5 9.3 8.2 2.4 5.9 4.3 8.4 3.6 11.0 20.7 8.3 9.7 11.7 2.5 11.7 9.3 10.3 9.6 3.7 3.1 2.2 8.0 6.7 4.1 6.2 7.5 4.1 12.3 25.0 10.0 7.5 5.2 4.7 7.5 7.2 4.9 6.8 5.2 6.7 3.4 12.2 9.6 7.7 4.7 0.1 9.4 2.9 8.2 7.8 10.4 5.6 11.0 7.1 12.0 7.2 8.7 3.2 15.1 9.7 8.5 5.3 5.9 7.8 4.7 4.9 9.3 8.3 4.6 5.6 8.5 6.1 13.7 0.1 4.0 4.9 12.4 0.9 1.4 1.2 1.9 0.8 2.2 0.4 1.0 0.9 1.3 0.2 0.8 0.8 0.6 0.9 0.7 0.8 1.1 1.0 7.7 26.1 7.9 9.7 6.8 8.7 6.6 11.5 6.5 5.4 9.3 8.4 10.0 6.4 7.8 47.7 5.9 3.3 3.9 5.5 5.2 14.4 8.5 7.4 33.9 25.8 5.8 3.7 10.4 7.1 5.0 10.9 7.9 21.7 5.7 12.7 17.5 11.2 18.6 5.5 96.4 4.0 3.7 10.5 7.7 7.3 8.2 10.4 15.0 9.2 3.6 6.7 93.9 7.8 8.2 6.6 3.9 5.0 12.8 4.6 7.2 58.1 3.8 5.5 14.4 76.9 52.9 6.6 4.8 19.2 2.6 1.7 7.2 6.7 10.8 45.0 13.1 18.6 9.3 18.4 8.8 2.6 2.8 1.4 7.6 10.6 6.7 1.5 RIOX2 "FLJ14393, JMJD10, mdig, MINA, MINA53, NO52" ENSG00000170854 "Ribosomal oxygenase 2" Q8IUF8 3 97941818-97972457 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.7;Distal tubular cells: 49.0;Endometrial ciliated cells: 25.7;Extravillous trophoblasts: 43.5;Syncytiotrophoblasts: 31.2;Theca cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007603, HPA008080, CAB013458" Supported Supported Nucleoplasm,Nucleoli NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "CAB013458: AB_2533432, HPA007603: AB_1853957, HPA008080: AB_1853960" "prognostic unfavorable (4.41e-4)" "unprognostic (8.64e-2)" "unprognostic (1.59e-3)" "unprognostic (2.11e-2)" "unprognostic (1.26e-1)" "unprognostic (2.53e-3)" "unprognostic (1.64e-3)" "unprognostic (8.68e-2)" "unprognostic (9.68e-2)" "unprognostic (5.34e-2)" "unprognostic (1.56e-3)" "unprognostic (6.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (3.44e-3)" "unprognostic (1.76e-1)" 14.6 9.7 9.8 14.5 11.3 2.2 13.9 9.5 11.2 11.6 8.3 12.4 6.9 10.7 10.6 22.3 10.4 7.3 10.1 9.5 12.3 14.4 14.3 11.0 14.2 12.4 12.4 10.4 18.2 10.8 10.2 15.6 12.0 10.4 12.3 16.8 19.8 9.6 32.0 17.8 10.3 10.4 12.9 8.4 12.8 6.7 10.9 6.9 46.4 11.3 15.0 16.4 15.5 13.6 42.6 27.8 9.1 17.4 20.5 30.3 22.8 20.1 14.3 22.0 18.5 18.6 22.8 59.7 21.2 25.1 34.3 24.3 28.9 28.2 32.5 109.9 13.8 19.2 13.5 19.1 33.4 37.1 7.0 24.5 38.8 17.6 44.4 13.1 23.9 26.4 26.2 23.3 22.1 11.5 29.7 14.5 19.9 47.3 34.4 0.0 32.2 58.7 21.4 24.1 49.6 17.6 25.7 28.7 34.4 10.1 24.7 15.3 16.3 22.9 24.0 13.7 39.9 37.7 18.3 55.5 29.1 37.8 23.8 1.9 13.2 0.7 10.3 11.9 15.8 15.9 14.9 12.0 16.9 13.3 15.0 12.5 0.8 10.8 15.8 26.0 15.2 10.5 9.8 11.3 9.5 11.2 9.5 12.3 12.4 12.4 12.0 12.9 10.9 13.6 18.3 9.6 14.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 14.9 11.2 0.0 0.0 10.5 7.3 0.0 33.7 5.7 0.0 49.0 16.4 0.0 25.7 14.9 5.8 0.0 0.0 0.0 13.2 43.5 7.3 0.0 12.6 2.5 20.2 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 7.2 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.5 0.0 0.0 11.6 13.8 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 31.2 2.2 24.8 0.0 0.0 RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 49.0;Proximal enterocytes: 62.0;Proximal tubular cells: 51.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039094, HPA039095, HPA061531" Supported Supported Nucleoplasm No No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA039094: AB_10671037, HPA039095: AB_2676345, HPA061531: AB_2684554" "unprognostic (7.10e-2)" "unprognostic (4.26e-2)" "unprognostic (2.78e-2)" "unprognostic (3.55e-2)" "unprognostic (2.56e-2)" "unprognostic (6.98e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (3.47e-2)" "unprognostic (2.92e-2)" "unprognostic (1.77e-1)" "unprognostic (1.30e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.59e-3)" "unprognostic (1.44e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 6.8 25.4 17.0 7.1 17.4 7.1 7.7 16.0 20.2 8.7 14.6 9.7 13.1 8.1 6.4 14.3 14.0 5.9 15.0 17.5 15.7 15.9 29.6 6.9 11.1 15.1 15.3 10.6 10.6 9.5 12.6 4.7 15.2 10.1 5.9 4.4 13.7 8.3 31.7 10.8 14.2 4.6 12.6 9.5 8.8 7.4 16.9 9.7 10.4 27.2 8.2 8.5 8.1 15.3 27.0 34.3 8.7 23.0 11.5 8.8 15.6 17.2 35.3 24.9 19.8 40.7 13.0 50.8 26.0 14.6 21.4 20.0 20.0 22.3 14.4 31.3 28.4 17.4 16.6 26.6 18.7 23.4 14.0 13.6 20.2 24.6 13.8 34.5 20.7 24.7 34.0 9.2 14.9 38.6 26.1 63.1 29.2 22.9 41.8 23.2 9.3 43.2 20.3 37.8 28.9 16.6 21.7 45.2 38.2 10.6 38.2 35.5 13.7 15.7 22.3 18.2 24.7 31.6 28.6 56.0 23.4 19.4 22.5 43.7 14.6 9.9 15.3 6.6 15.3 11.0 13.5 13.9 16.5 11.8 13.2 14.6 0.3 20.7 8.6 22.5 16.1 13.5 17.0 17.4 16.0 20.2 17.5 15.7 15.1 15.3 15.2 12.6 16.9 15.3 8.1 0.0 11.3 2.9 11.1 6.4 7.1 14.0 7.4 7.4 14.7 14.7 6.6 12.8 9.1 14.7 4.2 19.3 9.8 17.0 49.0 19.2 10.8 16.7 7.3 9.3 11.4 8.8 6.5 16.4 16.9 7.0 8.2 7.3 0.0 8.7 8.6 37.5 14.2 15.2 6.7 12.5 8.2 7.8 2.4 29.6 9.9 6.3 5.4 2.8 5.9 11.0 19.6 2.0 3.7 15.2 12.9 8.2 14.7 10.1 62.0 51.9 17.1 6.0 6.6 7.7 7.5 4.5 7.8 13.8 6.5 10.1 9.0 17.2 12.7 7.5 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RNASE2 "EDN, RAF3, RNS2" ENSG00000169385 "Ribonuclease A family member 2" P10153 14 20955487-20956436 "Enzymes, Plasma proteins, Predicted secreted proteins" Chemotaxis "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 49 "bone marrow: 1713.7" "Cell type enhanced" "Detected in some" "Erythroid cells: 30.7;Kupffer cells: 174.3;Macrophages: 82.2;monocytes: 54.6" "Cancer enriched" "Detected in many" 7 "glioma: 14.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 457.5;eosinophil: 1352.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 1352.6" "Group enriched" "Detected in some" 303 "HL-60: 539.0;NB-4: 539.8;THP-1: 1405.4;U-937: 1295.9" HPA044983 Enhanced "Secreted to blood" NA NA 200000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA044983: AB_10963689" "unprognostic (6.66e-2)" "unprognostic (3.00e-1)" "unprognostic (6.85e-2)" "unprognostic (7.68e-2)" "unprognostic (2.73e-2)" "unprognostic (9.26e-2)" "unprognostic (4.94e-3)" "unprognostic (6.77e-2)" "unprognostic (9.54e-2)" "unprognostic (3.24e-2)" "unprognostic (3.25e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.28e-13)" "unprognostic (2.27e-2)" "unprognostic (7.14e-3)" "unprognostic (5.33e-2)" "unprognostic (1.50e-1)" 7.1 6.0 3.0 9.1 2.8 1713.7 1.7 2.9 5.5 2.3 4.4 2.2 0.2 2.1 0.3 0.9 5.7 2.6 4.0 2.8 4.2 1.7 4.6 12.2 1.9 5.4 4.1 1.5 1.7 0.5 1.7 1.8 4.4 1.7 0.7 1.7 1.9 0.2 0.7 2.9 1.4 9.7 4.5 35.1 2.1 0.7 4.2 14.8 0.9 0.6 0.6 5.2 1.4 6.3 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 0.0 539.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 539.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 1405.4 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.7 0.0 1295.9 0.0 457.5 109.0 1352.6 0.4 19.3 0.8 0.3 0.4 0.0 191.8 0.4 0.4 0.4 9.8 0.1 2.8 2.6 0.1 39.9 3.0 2.8 2.9 5.5 2.8 4.2 5.4 4.1 4.4 4.5 4.2 6.3 0.2 3.2 0.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.4 0.0 1.9 0.0 0.5 0.0 0.0 1.3 0.0 30.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.4 2.2 13.0 0.0 0.0 0.0 0.0 174.3 0.7 1.7 0.3 82.2 0.0 0.0 54.6 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 19.7 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RNASE6 "RAD1, RNaseK6, RNS6" ENSG00000169413 "Ribonuclease A family member k6" Q93091 14 20781268-20782467 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.5" "Cell type enhanced" "Detected in many" "B-cells: 108.0;dendritic cells: 221.7;Hofbauer cells: 207.9;Kupffer cells: 551.2;Langerhans cells: 198.4;Macrophages: 270.3;monocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 1238.8" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "RPMI-8226: 65.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA000698 Approved "Secreted to blood" NA NA 2600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA000698: AB_2181340" "unprognostic (5.04e-2)" "unprognostic (5.21e-3)" "unprognostic (3.59e-2)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" "unprognostic (7.31e-2)" "unprognostic (7.91e-2)" "unprognostic (2.29e-1)" "unprognostic (4.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.04e-1)" "unprognostic (2.73e-1)" "unprognostic (2.85e-3)" "unprognostic (9.62e-2)" "unprognostic (5.60e-3)" "unprognostic (3.46e-2)" "unprognostic (5.54e-2)" 25.2 29.5 8.0 59.6 7.5 27.5 24.0 7.8 13.6 31.6 10.0 27.7 17.3 10.6 78.4 16.0 11.3 47.7 11.7 7.3 10.9 12.2 21.1 29.6 110.5 13.6 10.1 9.9 8.4 9.0 4.3 44.8 11.9 7.9 34.0 1.8 11.2 17.2 2.0 8.6 33.4 23.6 10.8 62.1 14.9 4.5 12.6 43.8 5.5 6.0 84.5 43.3 5.1 19.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 2.1 2.1 0.0 0.0 0.0 0.0 0.0 1.7 4.7 0.6 0.2 0.0 0.0 1.9 4.6 0.0 0.0 0.0 0.2 0.0 65.6 1.1 0.7 0.0 0.1 0.0 0.0 0.1 0.1 0.0 8.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.7 0.0 441.1 537.3 12.8 5.3 124.8 12.0 324.7 13.6 5.6 513.3 410.3 6.4 1.0 199.0 36.7 2.0 1238.8 1.1 329.8 8.0 7.5 7.8 13.6 7.3 10.9 13.6 10.1 11.9 10.8 12.6 19.5 1.6 6.4 7.5 0.0 108.0 4.5 0.2 0.0 1.8 0.0 1.4 2.8 0.6 14.3 1.2 0.0 0.0 1.1 221.7 2.6 0.0 0.0 0.8 0.1 0.0 3.8 0.0 12.0 0.0 0.0 1.6 1.4 1.1 0.2 0.0 0.0 8.6 3.3 207.9 0.0 0.0 0.5 2.0 551.2 198.4 4.8 2.8 270.3 21.4 1.9 115.8 0.0 9.2 0.0 0.0 0.0 12.6 0.7 52.4 0.2 0.4 0.5 0.2 0.4 13.1 0.6 0.6 0.1 0.7 0.6 3.8 2.2 7.8 0.0 3.4 1.2 RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" 7.2 9.5 8.8 6.6 8.7 5.8 11.3 8.5 9.2 9.8 9.7 8.1 15.9 8.4 20.0 7.4 11.6 7.8 10.0 8.8 9.0 16.4 11.5 7.6 8.1 8.8 9.1 11.2 10.9 24.3 9.5 11.1 8.8 10.6 10.3 15.7 15.1 13.6 17.2 8.3 13.9 11.8 9.0 6.7 9.2 8.7 9.1 7.7 12.9 14.9 10.4 9.1 7.1 8.7 10.9 22.7 20.5 14.6 19.1 15.2 13.8 16.7 17.7 25.4 26.9 46.0 20.9 9.2 14.9 18.5 26.7 22.1 22.7 21.2 26.7 13.8 13.1 14.0 21.5 21.9 14.3 12.8 11.5 14.8 17.9 28.7 18.2 27.9 46.7 13.5 23.2 8.6 22.7 23.5 9.0 14.1 13.7 43.4 21.9 11.0 44.5 7.9 28.3 18.4 13.7 14.6 22.9 20.4 30.4 20.6 22.5 9.5 32.8 19.0 17.2 11.8 14.6 9.6 10.2 9.4 16.5 8.3 17.1 4.4 2.2 2.2 3.0 2.9 3.5 3.2 2.3 2.4 2.3 1.3 2.7 2.9 1.2 3.2 2.1 3.7 2.1 2.9 8.8 8.7 8.5 9.2 8.8 9.0 8.8 9.1 8.8 9.0 9.1 8.7 9.6 6.4 9.6 12.7 9.4 8.8 11.2 22.8 10.2 16.1 12.1 10.9 9.7 12.8 13.3 20.2 20.9 32.0 17.9 15.2 7.9 26.0 6.3 8.9 10.3 6.5 9.6 13.0 19.3 32.3 26.5 11.8 9.2 10.9 7.0 11.6 8.9 14.4 14.2 10.1 16.9 13.2 26.4 6.6 12.9 3.0 13.1 7.6 10.6 15.0 15.0 19.0 10.3 18.1 19.0 29.0 11.0 12.4 17.1 10.3 31.0 20.9 10.3 21.1 19.7 10.0 14.2 25.1 19.6 6.4 5.8 31.1 10.0 13.4 9.4 9.9 RNF128 "FLJ23516, GRAIL" ENSG00000133135 "Ring finger protein 128" Q8TEB7 X 106693794-106797016 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.1;liver: 124.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 67.3;Cholangiocytes: 50.1;Distal enterocytes: 49.3;Gastric mucus-secreting cells: 54.6;Hepatocytes: 76.9;Proximal enterocytes: 85.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.9;CAPAN-2: 35.0;Hep G2: 30.6;OE19: 96.2;RPTEC TERT1: 30.5;RT4: 88.8;WM-115: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019675 Uncertain NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA019675: AB_2670225" "unprognostic (1.78e-1)" "unprognostic (1.44e-2)" "unprognostic (1.23e-1)" "unprognostic (1.88e-3)" "unprognostic (1.92e-4)" "unprognostic (2.14e-3)" "unprognostic (2.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (1.55e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.11e-2)" "unprognostic (7.61e-2)" "unprognostic (6.30e-2)" "unprognostic (5.30e-3)" 0.7 35.0 2.6 1.8 2.4 0.0 7.9 1.9 2.4 0.6 0.8 21.8 62.1 0.1 0.5 4.6 1.0 33.1 0.5 2.5 4.2 31.5 124.6 14.7 0.2 2.7 2.2 2.0 16.4 0.7 6.6 11.1 3.3 2.8 19.6 0.1 28.6 2.1 8.9 6.9 60.8 0.6 1.6 0.1 46.9 0.6 4.3 2.8 29.4 4.1 0.2 20.0 2.0 1.6 11.1 0.0 0.0 0.0 3.4 1.8 41.9 0.1 0.3 0.0 0.0 18.8 35.0 0.0 0.0 0.6 0.4 13.3 0.1 0.0 0.0 0.0 20.6 0.0 0.3 30.6 0.0 0.0 0.0 0.1 14.4 0.0 0.1 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.4 96.2 0.3 0.0 0.1 0.1 30.5 88.8 0.2 0.0 0.0 2.3 2.2 0.3 2.3 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 15.1 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 1.9 2.4 2.5 4.2 2.7 2.2 3.3 1.6 4.3 1.6 0.1 67.3 19.6 6.2 0.5 6.8 6.6 13.1 10.2 0.0 9.7 4.2 0.5 50.1 15.0 33.1 0.0 23.4 0.1 49.3 0.0 14.7 0.1 0.0 0.0 0.3 24.7 2.7 17.9 15.6 3.3 0.3 54.6 0.0 0.0 0.1 1.8 76.9 1.9 0.0 19.6 33.3 2.0 2.7 0.4 0.2 0.0 0.4 3.6 3.7 0.0 0.0 0.0 25.1 13.8 25.6 23.6 0.0 0.0 1.9 85.4 25.3 8.7 0.0 0.0 0.0 1.3 0.0 2.0 11.5 5.3 16.6 0.2 0.5 28.7 8.5 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228496188 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 189.0" "Low region specificity" "Detected in all" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA030098: AB_10602923" "unprognostic (4.84e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (2.83e-4)" "unprognostic (4.90e-3)" "unprognostic (1.13e-1)" "unprognostic (2.93e-2)" "unprognostic (3.46e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-1)" "unprognostic (5.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.92e-3)" "unprognostic (1.59e-1)" "unprognostic (9.76e-2)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" 26.8 66.6 16.2 7.5 16.2 11.3 25.8 14.8 24.3 40.5 3.4 28.1 8.6 31.8 4.3 59.1 28.7 5.6 35.4 15.9 16.9 40.7 52.0 23.6 7.3 19.4 15.2 39.3 34.5 22.5 47.7 5.5 18.4 33.5 3.7 9.0 39.7 8.2 64.2 45.0 22.5 5.6 15.6 37.0 27.6 20.8 18.5 8.5 36.1 19.8 6.1 29.9 41.2 19.8 26.7 23.1 14.8 28.9 16.8 12.5 26.6 21.5 17.3 15.6 12.7 12.8 19.2 65.9 43.1 28.9 11.4 20.9 19.1 22.1 5.8 25.9 28.5 20.8 13.2 12.6 46.1 22.1 34.4 20.4 44.7 11.6 15.8 18.3 14.0 52.6 35.6 115.2 12.4 17.7 35.2 20.8 30.7 19.1 24.0 27.8 12.5 61.5 11.4 17.2 29.9 30.0 21.9 44.1 62.3 4.3 34.6 50.2 27.8 18.3 16.9 19.6 19.3 189.0 56.7 36.4 46.7 22.7 28.7 0.0 0.5 3.6 0.6 1.0 0.7 0.5 0.7 1.0 0.6 1.0 0.6 0.7 0.1 0.4 1.4 0.7 0.6 0.3 16.2 16.2 14.8 24.3 15.9 16.9 19.4 15.2 18.4 15.6 18.5 19.8 54.0 25.6 15.5 8.1 47.2 36.2 42.9 10.6 38.7 85.2 59.5 58.5 70.8 65.8 14.2 40.5 18.8 19.7 52.2 39.8 113.5 15.2 0.8 35.5 47.2 32.1 40.0 118.4 16.6 24.5 27.1 54.4 34.7 32.0 44.5 45.0 41.7 67.4 27.4 55.5 17.2 36.6 2.0 40.1 30.5 4.2 24.5 35.8 39.2 12.2 29.7 145.3 62.8 7.1 12.6 21.4 23.4 25.9 35.4 44.0 32.9 126.4 10.3 47.7 19.7 52.2 38.4 4.2 21.5 57.0 55.3 17.6 54.6 217.5 38.6 31.7 RNF20 "BRE1, BRE1A, FLJ11189, FLJ20382, hBRE1, KAIA2779" ENSG00000155827 "Ring finger protein 20" Q5VTR2 9 101533853-101563344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 76.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012478, HPA051773" Supported Enhanced Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB012478: , HPA051773: AB_2681604" "unprognostic (7.02e-2)" "unprognostic (2.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.03e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.01e-1)" "unprognostic (5.47e-2)" "unprognostic (7.27e-3)" "unprognostic (1.60e-1)" "prognostic favorable (1.64e-6)" "unprognostic (2.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-1)" "unprognostic (9.54e-3)" 17.8 17.8 21.3 16.3 24.6 14.8 19.0 22.0 22.8 17.0 21.4 17.7 11.1 19.0 19.2 21.6 19.8 14.1 26.4 20.4 23.2 21.4 15.7 16.3 18.6 22.8 23.7 21.5 21.3 28.1 10.3 14.6 23.7 20.9 16.9 30.4 16.7 17.9 29.7 17.3 12.3 18.9 22.0 17.6 14.5 32.5 22.6 19.9 23.4 24.9 21.0 15.0 15.0 26.8 25.8 64.2 36.4 40.0 43.8 34.4 31.0 44.1 35.3 43.1 37.6 39.2 26.8 56.8 23.2 34.3 36.0 64.0 42.6 37.5 44.1 59.7 19.8 30.5 55.9 39.7 32.2 53.0 35.2 34.0 39.4 38.2 49.2 32.4 25.7 20.7 29.5 32.5 47.4 33.6 41.4 14.0 80.5 57.8 32.3 39.4 125.7 28.3 17.8 24.5 38.7 48.6 62.1 32.9 36.1 36.3 29.7 24.7 36.6 39.8 39.7 28.6 37.3 35.1 118.0 30.4 35.1 19.6 49.2 24.5 15.2 23.7 20.4 20.3 15.5 15.3 16.7 15.4 14.6 12.4 17.3 16.4 15.7 17.1 30.0 9.2 14.7 13.4 21.3 24.6 22.0 22.8 20.4 23.2 22.8 23.7 23.7 22.0 22.6 26.8 15.9 25.6 31.2 10.7 16.8 6.4 9.7 13.7 17.1 32.4 11.6 11.4 49.5 8.6 23.9 22.0 6.2 16.7 10.2 17.9 5.9 18.3 54.5 20.3 18.5 18.7 24.6 22.3 16.3 13.8 11.5 16.9 10.2 11.5 22.1 19.7 11.7 18.1 16.4 43.7 18.7 12.1 16.2 27.4 4.3 21.4 18.0 20.0 10.6 8.4 31.4 31.4 33.0 11.1 21.9 11.0 13.0 23.7 13.1 9.3 10.1 11.5 28.5 26.5 32.9 21.8 17.5 76.0 16.7 18.3 5.8 7.7 16.1 15.4 15.3 6.4 RNLS "C10orf59, FLJ11218, renalase" ENSG00000184719 "Renalase, FAD dependent amine oxidase" Q5VYX0 10 88273864-88584530 "Enzymes, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 103.0;Inhibitory neurons: 101.1;Oligodendrocyte precursor cells: 51.8;Oligodendrocytes: 61.8;Proximal tubular cells: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 18.3;fHDF/TERT166: 17.1;HSkMC: 19.5" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 10500000000 "Cluster 7: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.27e-2)" "unprognostic (9.16e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-1)" "unprognostic (1.46e-3)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (3.98e-1)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (7.74e-3)" "unprognostic (1.37e-2)" "unprognostic (9.80e-2)" "unprognostic (1.71e-1)" 7.1 13.4 2.0 2.8 2.4 2.2 6.7 6.1 3.5 7.4 7.2 7.6 5.5 5.0 5.3 4.9 6.1 5.5 11.8 2.0 2.9 16.6 8.7 3.0 3.8 5.0 6.6 5.8 8.2 9.0 5.3 2.0 5.2 7.0 8.3 4.8 6.0 3.9 11.8 4.3 5.6 3.5 3.4 2.8 6.7 5.3 2.7 2.5 9.1 9.8 4.0 4.7 4.4 3.2 18.3 8.2 0.3 0.1 2.4 2.8 0.0 5.1 0.5 2.7 2.3 1.0 5.2 0.0 8.0 17.1 0.0 2.4 0.0 0.9 2.2 3.8 0.1 2.9 5.1 0.2 11.2 0.0 0.5 19.5 1.4 10.2 0.1 0.3 5.7 0.1 1.4 9.2 0.1 6.3 0.0 3.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 4.3 0.1 0.1 4.0 12.4 4.9 2.2 8.9 1.3 2.5 4.1 6.3 3.9 5.3 8.4 0.2 0.0 9.8 0.0 0.0 2.1 1.2 2.3 3.6 1.7 2.4 1.7 1.6 3.1 2.2 1.8 1.4 0.1 2.7 2.3 2.7 0.9 1.8 2.0 2.4 6.1 3.5 2.0 2.9 5.0 6.6 5.2 3.4 2.7 3.2 1.2 3.2 1.5 32.0 5.5 3.2 6.8 5.7 4.0 6.5 5.5 3.9 16.7 4.3 5.8 1.8 2.1 2.0 3.2 6.2 23.5 6.4 8.9 3.8 3.1 1.3 5.4 4.6 103.0 9.6 0.5 6.2 7.1 3.2 1.3 2.2 2.5 10.1 6.5 5.0 101.1 5.5 2.0 4.7 3.8 4.3 1.5 3.8 3.6 40.3 3.7 6.8 3.1 51.8 61.8 4.2 8.9 6.4 3.9 4.4 8.5 43.1 1.6 5.7 0.0 4.6 4.6 4.7 8.2 10.4 5.5 1.6 3.0 2.9 7.2 6.9 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 RPA3 REPA3 ENSG00000106399 "Replication protein A3" P35244 7 7636518-7718607 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 428.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005708 Approved NA NA 17000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA005708: AB_1856411" "unprognostic (2.06e-2)" "unprognostic (2.27e-2)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (7.20e-3)" "unprognostic (3.75e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (5.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (7.41e-2)" "unprognostic (1.08e-1)" "unprognostic (7.24e-2)" "unprognostic (2.61e-1)" "unprognostic (5.83e-2)" 16.4 25.7 12.4 22.9 14.4 46.2 24.4 14.3 19.7 12.5 19.9 25.2 15.8 10.5 37.1 19.6 25.5 10.6 20.5 12.3 15.7 35.7 40.5 14.6 37.9 13.9 13.1 12.7 15.4 46.4 27.2 16.4 15.3 11.5 19.9 34.1 14.5 13.6 18.7 13.3 18.4 9.6 14.7 23.4 20.8 22.5 13.8 51.8 19.3 12.5 35.6 16.3 12.5 15.7 174.1 95.9 94.8 102.3 35.2 31.9 67.2 47.6 44.3 73.0 116.2 92.3 153.1 88.4 45.2 36.0 235.9 129.2 64.5 85.9 106.4 41.1 112.0 48.1 111.9 189.2 15.3 102.5 38.9 23.4 29.9 85.0 59.6 36.0 41.9 168.6 119.5 132.6 70.8 257.0 83.9 198.1 149.9 104.9 125.1 98.3 154.9 141.6 52.3 84.0 70.5 86.8 88.2 91.6 51.0 137.9 122.0 107.4 19.3 60.5 169.1 99.8 113.7 102.7 199.9 167.7 89.7 119.3 118.5 17.9 25.3 27.2 34.1 40.8 40.9 75.4 55.7 44.0 31.9 76.9 45.6 46.3 22.2 29.7 49.0 61.6 68.5 35.7 12.4 14.4 14.3 19.7 12.3 15.7 13.9 13.1 15.3 14.7 13.8 15.7 35.6 38.5 39.5 2.9 93.2 40.5 65.0 160.8 41.5 24.1 54.7 73.9 39.0 60.1 89.5 71.7 10.4 152.2 53.2 61.9 273.9 84.8 96.9 144.8 34.9 35.7 25.3 218.2 5.2 105.4 257.5 43.3 39.8 61.8 53.9 43.2 36.0 154.5 131.4 16.8 5.6 75.1 83.4 48.7 54.2 24.4 39.1 49.9 56.9 1.9 68.2 63.7 56.7 6.0 5.8 64.1 70.4 24.5 75.8 25.9 74.3 428.6 269.9 44.7 6.6 34.7 46.9 112.7 65.9 59.6 34.4 66.2 68.7 46.1 90.5 66.2 RPL26L1 RPL26P1 ENSG00000037241 "Ribosomal protein L26 like 1" Q9UNX3 5 172958729-172969771 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 408.0;Spermatocytes: 316.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030449 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA030449: AB_10602125" "unprognostic (3.02e-1)" "unprognostic (1.41e-1)" "unprognostic (3.39e-2)" "unprognostic (4.12e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (2.04e-3)" "unprognostic (2.45e-1)" "unprognostic (7.51e-2)" "unprognostic (5.86e-3)" "unprognostic (3.18e-1)" "unprognostic (1.06e-1)" "unprognostic (7.17e-2)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (2.14e-3)" 27.4 45.8 28.0 28.9 29.2 39.1 27.3 29.7 39.1 23.5 26.4 24.5 25.2 28.5 37.7 37.5 26.6 22.1 37.8 31.0 29.8 43.7 47.9 22.1 34.4 29.3 28.9 25.7 24.9 34.5 30.3 23.8 30.6 25.5 26.2 17.9 24.6 28.9 37.8 21.3 21.9 26.0 28.1 26.8 26.2 91.2 29.3 34.0 29.5 28.1 29.0 30.4 25.4 29.1 129.8 114.7 101.9 140.8 68.9 72.3 131.7 120.6 70.6 170.5 151.1 141.1 135.3 96.6 301.5 166.6 181.6 82.1 170.1 239.8 156.4 124.1 220.9 71.6 122.8 174.5 135.1 105.7 60.8 91.0 99.2 176.1 122.3 69.1 99.2 93.6 100.3 79.0 123.1 286.6 129.5 165.6 65.2 59.7 180.5 93.3 157.5 128.4 101.0 80.1 102.0 62.7 110.6 100.2 167.6 64.7 122.8 111.5 105.4 193.2 109.0 114.3 92.5 70.3 119.0 182.3 152.6 130.2 117.6 25.4 86.6 39.9 33.1 80.5 42.7 50.4 40.4 46.1 99.5 38.1 32.9 42.0 42.9 39.5 72.2 68.1 55.8 55.7 28.0 29.2 29.7 39.1 31.0 29.8 29.3 28.9 30.6 28.1 29.3 29.1 41.5 41.7 32.8 4.6 29.8 48.8 56.9 191.3 32.5 18.8 50.2 61.8 45.5 41.5 82.7 58.8 18.8 111.6 28.7 36.2 181.9 119.0 408.0 98.4 70.0 47.7 40.2 49.2 4.5 113.0 124.5 45.3 29.6 70.6 26.6 60.2 41.4 132.1 115.0 15.2 5.2 48.6 93.6 48.6 51.9 79.9 37.9 45.6 51.6 2.8 93.5 61.7 49.4 2.0 5.0 138.0 38.6 41.0 59.2 67.9 48.2 216.2 92.4 20.2 19.7 35.6 56.1 316.7 178.6 70.5 52.8 78.9 28.9 81.1 59.1 57.7 RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 599.6;Syncytiotrophoblasts: 621.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB019277: , HPA008297: AB_1856457, HPA025922: AB_1856458" "unprognostic (9.59e-3)" "unprognostic (5.22e-2)" "unprognostic (1.66e-2)" "unprognostic (1.06e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.82e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "prognostic unfavorable (1.44e-10)" "unprognostic (2.83e-1)" "unprognostic (6.99e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (2.44e-4)" 112.6 132.5 48.2 131.9 50.4 180.8 146.1 49.9 55.9 161.8 98.0 156.9 125.5 108.7 344.1 106.8 122.9 119.8 107.3 49.5 56.5 145.1 212.1 129.7 109.2 54.0 50.6 94.8 159.6 180.9 79.1 257.9 53.9 164.4 175.2 117.0 158.2 157.5 110.4 91.5 110.9 156.6 53.8 118.1 145.1 144.2 55.4 108.5 232.5 75.1 143.3 165.4 87.9 61.9 328.2 290.6 302.7 401.2 413.1 308.2 586.7 426.7 516.8 544.8 459.2 939.2 564.8 255.3 501.6 572.3 506.4 468.4 318.8 516.4 492.0 121.2 196.5 295.3 308.4 634.1 398.9 468.4 467.0 294.6 505.1 432.3 447.5 519.8 530.4 239.2 458.7 805.1 389.1 300.9 270.6 451.0 240.4 839.3 415.7 242.3 549.1 852.7 371.6 304.3 246.4 261.0 517.9 1231.1 489.4 353.6 606.1 765.6 338.0 600.8 358.2 317.1 371.9 474.7 608.4 259.9 583.4 314.9 493.2 424.2 427.5 285.5 365.5 410.5 417.0 291.0 336.1 363.8 481.2 232.4 298.8 308.7 78.3 398.8 357.6 591.0 338.2 676.5 48.2 50.4 49.9 55.9 49.5 56.5 54.0 50.6 53.9 53.8 55.4 61.9 85.7 118.6 158.0 22.2 107.8 61.8 134.1 264.6 62.0 72.6 90.0 74.2 81.4 133.0 197.7 80.9 45.9 461.6 109.6 113.9 23.5 278.0 37.3 73.2 103.5 98.6 63.0 91.7 18.8 241.1 599.6 127.4 84.1 151.2 105.2 109.3 100.6 206.3 233.2 63.9 18.6 168.5 162.8 150.4 75.3 24.4 105.0 117.0 90.7 20.6 122.2 136.8 65.9 24.1 20.5 160.1 109.5 110.9 392.3 121.3 64.6 82.3 98.5 100.8 85.5 65.3 122.0 335.2 288.9 67.7 57.8 621.0 81.5 213.7 138.7 117.6 RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 129.1;Distal tubular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cell line enhanced" "Detected in many" "Karpas-707: 63.9;SCLC-21H: 33.1;U-266/70: 80.0;U-266/84: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Centrosome" "HPA068664: AB_2686016" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.80e-4)" "unprognostic (3.75e-2)" "unprognostic (1.66e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.47e-8)" "unprognostic (8.41e-3)" "unprognostic (1.23e-1)" "unprognostic (9.46e-2)" "unprognostic (4.40e-2)" 9.8 9.1 14.0 2.3 18.9 11.6 8.2 31.8 16.1 9.4 17.9 4.0 1.7 1.5 6.9 13.8 13.7 3.6 38.4 15.9 13.9 26.5 4.4 7.0 2.8 16.4 12.2 1.6 6.4 22.7 11.4 3.2 17.2 6.1 1.8 21.8 52.2 2.8 84.5 6.7 2.0 2.1 21.5 4.8 1.7 6.9 14.8 5.5 28.1 60.3 2.5 5.8 6.2 23.8 0.1 1.7 4.4 3.3 0.4 0.0 0.3 0.0 0.0 0.5 0.9 0.1 0.1 0.0 1.5 0.0 22.6 0.1 24.5 0.1 0.0 0.0 12.1 5.8 0.1 0.1 1.8 16.9 19.0 0.4 1.5 0.0 0.1 0.0 0.0 16.9 0.5 63.9 0.1 1.8 8.2 8.4 3.6 0.0 1.8 16.8 23.1 0.2 5.8 0.6 33.1 1.8 0.6 2.2 28.8 1.3 0.7 13.2 0.0 1.8 2.8 11.5 3.0 80.0 39.8 0.0 6.1 12.5 1.9 2.6 0.6 1.4 0.0 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.3 3.3 0.1 2.4 0.3 0.0 0.1 14.0 18.9 31.8 16.1 15.9 13.9 16.4 12.2 17.2 21.5 14.8 23.8 1.4 9.6 16.7 5.2 3.7 16.2 17.0 5.8 4.0 21.7 17.4 9.7 129.1 17.2 13.9 14.7 31.3 0.6 4.7 0.1 117.4 20.2 25.6 10.4 2.5 4.8 1.2 5.0 17.6 16.9 1.5 10.0 1.1 15.0 4.5 2.9 2.5 9.7 51.9 47.1 20.6 0.5 42.7 25.8 9.2 15.5 3.1 23.2 39.2 3.7 10.4 29.6 0.0 13.0 17.2 8.1 0.0 4.1 8.0 28.4 0.0 18.6 19.4 16.3 0.0 11.8 7.0 21.7 30.3 32.4 22.6 0.7 3.9 0.2 0.2 30.2 RRAS2 TC21 ENSG00000133818 "RAS related 2" P62070 11 14277922-14364506 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010420, HPA050942" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB010420: AB_2253855, HPA050942: AB_2681285" "unprognostic (6.13e-2)" "unprognostic (1.85e-1)" "unprognostic (1.92e-1)" "unprognostic (1.47e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (7.80e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (4.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.50e-2)" "unprognostic (4.15e-1)" "unprognostic (9.02e-2)" "unprognostic (1.05e-1)" "unprognostic (6.80e-2)" "unprognostic (1.63e-1)" 30.8 14.1 8.0 16.1 8.0 5.2 21.2 9.7 10.7 21.7 14.9 22.3 20.8 19.7 9.2 15.4 14.2 11.9 44.4 12.0 10.5 39.3 39.1 22.9 28.3 7.0 8.1 18.3 18.2 17.2 8.5 29.4 8.0 20.1 18.7 12.1 18.0 19.3 40.8 12.1 39.5 18.0 6.3 16.3 17.7 25.1 10.4 14.4 29.0 34.0 37.7 23.4 14.0 6.3 89.3 38.2 35.7 30.8 122.0 121.1 52.8 309.1 160.7 260.5 328.1 78.0 108.7 102.2 46.8 209.0 84.3 97.1 61.0 110.8 260.5 88.7 49.6 6.8 21.5 62.4 133.6 0.3 0.7 129.5 205.0 104.2 331.2 106.5 131.7 24.8 45.9 0.2 229.3 43.5 21.5 5.6 98.3 18.2 31.4 19.0 118.5 1.9 133.7 48.8 9.7 18.4 74.7 46.0 42.5 119.9 30.6 6.2 303.1 139.6 74.0 272.1 85.1 0.2 0.2 48.4 56.0 0.1 29.0 2.1 0.0 0.0 5.5 0.0 2.4 11.8 1.0 2.8 0.0 6.6 0.5 2.1 0.4 3.8 0.0 0.2 0.0 0.9 8.0 8.0 9.7 10.7 12.0 10.5 7.0 8.1 8.0 6.3 10.4 6.3 6.6 19.2 18.9 14.4 57.8 69.3 76.2 17.7 23.9 5.5 22.6 13.7 31.5 40.0 20.6 18.4 0.0 36.5 31.2 30.5 23.5 46.5 55.2 25.8 16.0 15.2 19.1 3.2 32.8 18.4 58.0 29.7 12.8 34.7 8.9 15.6 13.6 33.4 8.2 13.5 35.4 16.0 14.2 2.4 12.0 45.2 16.4 2.3 26.6 9.4 2.0 21.7 56.7 28.6 4.9 57.1 30.1 11.3 22.0 120.3 89.9 112.9 15.0 10.1 19.7 20.7 21.4 39.5 42.1 20.3 49.9 29.0 29.5 13.3 20.8 96.5 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 RSPH3 "dJ111C20.1, RSHL2, RSP3" ENSG00000130363 "Radial spoke head 3" 6 158972871-159000202 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 149.3;Respiratory ciliated cells: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039109 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "HPA039109: AB_10794423" "unprognostic (6.18e-3)" "unprognostic (3.62e-3)" "unprognostic (4.54e-2)" "unprognostic (6.20e-2)" "unprognostic (1.88e-1)" "unprognostic (9.18e-2)" "unprognostic (1.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (6.74e-3)" "unprognostic (6.98e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.19e-4)" "unprognostic (5.89e-2)" "unprognostic (1.67e-1)" "unprognostic (5.14e-2)" "unprognostic (1.79e-2)" 2.9 4.7 0.8 2.2 1.0 1.6 3.7 0.2 4.7 3.9 14.5 4.2 5.9 3.4 4.6 5.7 6.1 3.3 3.8 2.0 1.0 6.3 2.7 4.6 1.4 1.9 2.6 3.4 4.3 13.2 3.5 3.1 1.5 5.2 3.7 6.7 4.4 4.1 1.5 3.8 5.6 3.7 1.6 2.3 4.1 9.9 1.1 1.8 7.6 2.2 2.0 2.9 3.0 1.6 8.5 3.7 2.1 4.9 4.8 6.3 2.2 6.2 7.0 1.9 2.8 1.2 4.6 1.7 4.8 7.2 6.3 6.1 1.4 5.6 2.8 4.4 2.9 2.2 3.9 2.6 4.6 2.4 1.6 7.1 9.5 3.8 6.9 10.0 2.5 2.5 2.8 2.6 4.5 4.3 1.5 2.7 1.2 3.8 2.7 2.2 0.3 1.6 8.6 2.6 2.8 4.0 11.6 3.8 2.2 2.4 4.7 5.3 5.4 2.0 5.5 4.8 3.0 2.9 6.1 1.2 10.1 2.9 3.9 0.9 4.0 0.6 0.6 3.0 1.2 0.9 0.9 1.2 4.0 2.4 0.7 1.1 10.5 1.7 7.0 4.6 1.3 1.5 0.8 1.0 0.2 4.7 2.0 1.0 1.9 2.6 1.5 1.6 1.1 1.6 2.3 25.6 17.9 15.0 4.0 7.4 17.2 19.1 6.2 14.2 12.2 7.6 17.5 17.2 25.1 22.0 35.5 10.3 5.7 25.6 13.7 15.8 149.3 67.0 6.9 6.0 13.1 2.1 32.8 10.2 11.4 7.6 10.2 12.7 2.5 9.2 7.9 8.4 10.1 3.3 18.5 17.6 16.2 9.5 16.5 62.9 14.0 12.6 7.2 4.7 8.3 14.4 4.1 6.0 3.5 13.1 21.1 17.7 5.7 18.4 33.1 19.7 120.4 32.5 6.6 5.9 10.2 57.3 10.9 18.6 8.8 5.9 6.1 12.2 13.1 23.1 RTN3 "ASYIP, HAP, NSPL2, NSPLII, RTN3-A1" ENSG00000133318 "Reticulon 3" O95197 11 63681446-63759891 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, ER-Golgi transport, Host-virus interaction, Stress response, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 514.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1074.7" "Group enriched" "Detected in all" 6 "granulocytes: 1074.7;monocytes: 400.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015649, HPA015650" Enhanced Supported "Endoplasmic reticulum" NA NA 130000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA015649: AB_1856498, HPA015650: AB_1856499" "unprognostic (8.11e-3)" "unprognostic (8.51e-2)" "unprognostic (3.61e-2)" "unprognostic (7.88e-3)" "unprognostic (1.41e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.30e-6)" "unprognostic (5.49e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-2)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (9.87e-4)" "unprognostic (1.60e-2)" "unprognostic (2.54e-1)" "unprognostic (2.73e-2)" "unprognostic (1.57e-2)" 207.5 81.8 361.4 54.1 412.2 108.5 93.3 338.4 514.5 87.6 190.7 88.1 54.0 62.5 81.2 55.7 88.5 56.3 57.4 428.4 378.9 92.8 87.5 77.8 36.0 404.5 309.1 48.1 91.1 109.9 81.0 62.2 417.2 53.3 79.9 194.4 138.8 76.1 70.2 103.7 65.2 80.1 329.2 51.7 57.0 46.6 334.0 53.7 175.5 43.7 48.5 55.7 54.2 384.0 157.5 113.8 134.0 128.4 242.3 170.9 53.4 139.3 147.5 120.5 128.4 99.6 338.1 184.2 231.7 210.0 115.7 157.2 194.0 68.7 157.5 149.5 103.5 236.5 151.3 70.4 201.1 212.8 182.4 113.5 199.2 146.7 162.3 200.7 165.2 158.9 136.2 290.1 107.4 129.2 113.4 235.2 156.7 127.3 127.3 148.4 93.8 342.9 239.7 87.5 282.7 164.0 226.2 245.3 271.5 95.4 271.1 172.7 155.2 71.3 95.6 251.1 108.4 183.4 169.9 145.6 274.7 173.8 77.2 441.0 400.1 487.7 41.4 187.6 44.8 28.6 41.6 41.3 130.8 19.4 30.1 32.7 1074.7 41.7 240.4 79.0 68.6 323.0 361.4 412.2 338.4 514.5 428.4 378.9 404.5 309.1 417.2 329.2 334.0 384.0 62.8 134.6 67.5 110.7 35.9 144.5 103.5 63.0 101.3 157.7 125.2 59.9 36.1 81.5 91.9 244.6 70.9 68.6 55.6 118.2 29.4 154.4 35.8 96.4 74.3 68.1 99.8 85.8 398.8 117.1 105.6 96.7 60.1 129.2 77.3 71.4 85.6 81.3 143.7 82.4 372.7 83.5 122.1 178.3 110.8 71.2 79.2 151.4 113.8 100.2 178.0 150.3 42.2 200.6 294.8 103.3 82.0 89.9 94.8 79.4 94.5 55.9 156.0 97.6 78.9 53.1 78.6 194.7 133.5 85.9 146.2 86.5 48.8 51.7 96.5 99.8 RTN4IP1 NIMP ENSG00000130347 "Reticulon 4 interacting protein 1" Q8WWV3 6 106570771-106629498 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036357 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA036357: AB_10673128" "prognostic unfavorable (9.18e-6)" "unprognostic (5.87e-2)" "unprognostic (2.20e-3)" "unprognostic (2.88e-1)" "unprognostic (3.51e-2)" "unprognostic (3.71e-2)" "unprognostic (7.37e-3)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "unprognostic (3.35e-1)" "unprognostic (2.51e-2)" "unprognostic (1.72e-2)" "prognostic favorable (8.55e-6)" "unprognostic (1.62e-1)" "unprognostic (9.82e-2)" "unprognostic (3.71e-1)" "unprognostic (5.76e-2)" 2.5 6.8 2.8 3.1 3.0 1.8 3.2 3.3 3.9 2.6 3.3 6.3 4.8 2.7 5.5 4.2 2.7 1.6 14.7 2.7 2.7 6.4 7.4 2.0 4.6 2.5 2.5 2.2 3.2 5.2 4.5 2.2 2.8 2.7 6.0 6.0 4.6 2.7 15.6 2.9 4.5 2.9 2.5 4.2 5.9 5.5 2.8 3.0 4.0 15.4 6.1 2.9 2.8 3.4 7.6 10.8 7.3 12.6 5.9 3.5 8.6 5.0 7.0 7.7 7.4 17.4 4.1 11.6 7.6 6.5 15.1 10.8 13.0 10.7 12.1 8.1 7.4 12.1 8.4 14.0 6.1 12.5 8.1 5.2 8.3 10.3 6.7 4.7 6.9 16.3 21.7 4.7 8.5 11.3 4.7 14.4 9.1 10.7 7.9 16.1 13.3 8.8 12.4 8.1 7.1 5.7 4.7 12.3 11.2 7.5 15.5 8.0 3.6 4.4 6.1 8.8 8.9 3.5 5.7 24.8 11.5 18.1 9.6 0.1 4.6 2.2 3.2 5.1 3.3 11.4 4.4 3.4 10.7 16.0 4.0 3.9 0.8 6.5 3.7 5.6 8.2 3.3 2.8 3.0 3.3 3.9 2.7 2.7 2.5 2.5 2.8 2.5 2.8 3.4 1.6 0.0 2.8 7.8 8.1 0.8 1.9 6.4 0.6 5.5 2.8 1.7 18.4 4.3 3.1 1.8 8.4 12.5 1.3 5.2 27.4 6.7 8.5 7.6 2.0 2.1 4.2 1.3 15.6 8.6 15.0 2.1 4.1 4.2 2.5 3.6 2.5 5.5 7.3 0.0 17.2 3.0 10.2 5.4 1.8 3.4 0.6 3.6 0.0 8.4 0.9 3.7 1.0 6.6 17.5 4.9 3.0 1.9 4.2 1.2 3.3 14.5 5.4 6.2 13.1 2.1 2.5 11.9 16.7 4.1 1.0 5.6 2.8 5.6 6.4 2.0 RWDD4 "FAM28A, MGC10198, RWDD4A" ENSG00000182552 "RWD domain containing 4" Q6NW29 4 183639635-183659203 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036501, HPA036502" Approved Approved "Intermediate filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Intermediate filaments" "HPA036501: AB_2675159, HPA036502: AB_10670800" "unprognostic (1.30e-1)" "unprognostic (4.15e-1)" "unprognostic (7.50e-2)" "unprognostic (2.30e-1)" "unprognostic (7.80e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-1)" "unprognostic (1.97e-2)" "unprognostic (6.27e-2)" "unprognostic (2.21e-2)" "unprognostic (4.68e-2)" "unprognostic (2.98e-1)" "prognostic favorable (1.01e-6)" "unprognostic (6.77e-2)" "unprognostic (1.14e-1)" "unprognostic (3.51e-2)" "unprognostic (4.65e-2)" 11.9 52.1 9.2 8.9 9.6 14.7 19.1 10.9 12.5 12.3 14.5 12.0 11.0 12.1 14.3 14.5 13.7 12.7 16.2 9.2 11.7 23.7 15.9 9.6 10.7 9.8 10.2 40.4 26.2 11.8 19.0 11.6 9.5 15.2 12.1 6.2 20.6 11.0 44.9 11.2 10.0 10.7 9.5 9.8 13.7 10.0 10.9 15.9 22.2 32.2 12.5 14.0 10.4 10.1 25.6 14.6 22.0 27.2 35.1 36.5 16.7 31.8 25.4 38.9 24.7 9.5 32.8 38.6 7.1 26.6 18.8 11.8 31.1 29.7 40.8 25.5 14.0 27.7 16.4 24.4 24.7 42.5 20.3 24.2 30.0 21.6 24.0 30.2 29.8 29.7 27.0 48.5 42.0 10.8 44.7 36.7 14.7 9.8 19.2 30.7 17.0 24.8 38.5 12.1 21.0 29.6 29.9 34.4 29.0 16.9 17.3 25.8 20.9 16.3 8.0 17.6 24.9 16.2 13.1 13.1 30.6 31.8 23.7 3.2 3.4 6.8 4.4 4.5 4.4 3.8 4.0 4.2 4.4 2.5 3.7 3.9 2.9 6.5 5.5 4.7 5.7 3.5 9.2 9.6 10.9 12.5 9.2 11.7 9.8 10.2 9.5 9.5 10.9 10.1 29.4 22.4 19.5 7.2 25.6 33.6 35.4 32.0 27.3 17.9 39.2 40.8 11.5 37.1 25.3 18.4 6.2 25.9 32.9 19.7 74.3 38.8 10.6 38.4 28.6 27.3 21.7 30.3 10.3 77.5 42.4 33.4 28.1 28.2 35.5 35.9 26.4 35.6 36.1 10.1 9.5 21.6 38.7 30.1 21.9 9.9 74.0 23.8 56.9 6.5 34.7 30.9 32.0 6.6 7.7 55.8 17.1 70.7 32.5 90.3 19.6 116.1 32.0 22.1 19.7 44.5 27.4 47.7 59.7 46.0 35.5 27.1 26.7 70.2 25.4 59.1 S100A12 "CAAF1, CAGC, CGRP, ENRAGE, MRP6, p6" ENSG00000163221 "S100 calcium binding protein A12" P80511 1 153373711-153375621 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 3489.7" "Group enriched" "Detected in many" 20 "Kupffer cells: 711.7;Macrophages: 475.0;monocytes: 998.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 51.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 1321.1;neutrophil: 1781.4" "Group enriched" "Detected in many" 13 "granulocytes: 1781.4;monocytes: 1321.1" "Cell line enhanced" "Detected in some" "hTCEpi: 2.6;THP-1: 1.6" "Region enhanced" "Detected in some" "cerebral cortex: 4.0" "HPA002881, CAB025872" Enhanced "Secreted to blood" NA NA 28500000 8300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "CAB025872: , HPA002881: AB_1848175" "unprognostic (1.33e-1)" "unprognostic (4.51e-2)" "unprognostic (7.49e-2)" "unprognostic (1.36e-1)" "unprognostic (7.30e-2)" "unprognostic (4.36e-2)" "unprognostic (3.79e-2)" "unprognostic (8.79e-3)" "unprognostic (9.04e-2)" "unprognostic (3.14e-2)" "unprognostic (1.58e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (5.03e-4)" "unprognostic (3.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.31e-2)" "unprognostic (7.70e-2)" 54.9 3.2 2.6 82.0 3.1 3489.7 7.0 2.9 7.7 21.9 3.2 5.5 1.7 2.1 0.0 52.4 19.3 6.7 16.6 2.7 2.6 15.2 25.6 148.4 1.9 3.2 2.9 2.1 3.6 1.3 4.3 19.8 3.9 3.5 0.4 0.3 11.4 0.2 4.0 3.7 4.4 40.4 3.0 523.2 8.9 0.9 2.9 30.2 6.0 14.8 46.5 41.9 33.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1321.1 5.2 1.9 44.9 1.0 3.2 0.8 1.5 122.7 1.0 1.1 0.5 1781.4 0.4 9.6 8.3 2.0 1031.8 2.6 3.1 2.9 7.7 2.7 2.6 3.2 2.9 3.9 3.0 2.9 2.9 0.0 19.2 24.4 0.0 6.1 0.1 0.3 9.8 0.0 0.0 0.1 0.0 1.1 8.6 9.2 1.8 0.0 0.5 2.9 0.0 0.0 0.1 1.4 0.0 0.0 2.1 0.0 14.1 0.1 0.2 0.9 4.1 1.1 0.0 13.9 0.0 6.8 3.8 8.6 0.0 0.1 0.0 0.0 711.7 0.8 1.8 0.0 475.0 0.0 1.0 998.3 0.0 36.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.7 7.8 0.0 0.0 0.8 0.4 0.0 0.2 5.7 0.0 0.5 6.9 0.0 0.1 0.2 S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP8, P8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 35382.0;esophagus: 24565.6;vagina: 11166.4" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 4126.5;Kupffer cells: 6348.0;Macrophages: 3758.3;monocytes: 6932.6;Squamous epithelial cells: 8480.1" "Cancer enhanced" "Detected in all" "cervical cancer: 2290.9;head and neck cancer: 2382.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 9 "classical monocyte: 26833.7;neutrophil: 52973.6" "Group enriched" "Detected in all" 9 "granulocytes: 52973.6;monocytes: 26833.7" "Group enriched" "Detected in some" 24 "hTCEpi: 241.8;SK-BR-3: 719.0;THP-1: 400.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" NA NA 10900000 370000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Intermediate filaments" Cytosol "CAB002791: , HPA024372: AB_1856536" "unprognostic (1.98e-1)" "unprognostic (1.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.58e-2)" "unprognostic (8.60e-3)" "unprognostic (9.26e-3)" "unprognostic (4.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.83e-1)" "unprognostic (6.13e-2)" "unprognostic (3.77e-2)" "unprognostic (2.24e-2)" "prognostic unfavorable (8.94e-7)" "unprognostic (1.17e-1)" "unprognostic (8.90e-2)" "unprognostic (8.27e-2)" "unprognostic (8.94e-3)" 582.3 54.3 41.7 1245.8 45.6 35382.0 70.0 43.4 88.0 5650.6 45.5 55.2 15.4 23.1 5.5 24565.6 236.1 99.0 121.1 40.9 42.7 103.0 176.7 1061.7 29.5 47.7 44.8 25.8 52.0 9.6 41.7 205.8 50.7 43.1 14.7 5.6 3988.2 5.0 48.5 267.3 47.7 430.2 44.2 3239.5 93.8 16.2 45.5 281.3 48.8 174.8 8952.6 561.9 11166.4 46.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.0 1.3 0.0 0.3 12.4 0.0 18.7 0.0 0.1 0.0 3.5 0.0 0.0 0.0 5.6 0.1 0.0 241.8 0.0 7.5 0.0 0.0 0.0 9.6 1.2 0.0 0.9 0.4 1.5 0.3 0.0 0.0 0.4 5.8 1.0 0.0 0.0 0.4 0.5 3.6 719.0 0.0 0.0 4.7 400.6 10.6 0.0 0.2 0.9 0.1 0.2 1.3 2.7 0.3 13.9 0.0 848.0 26833.7 3023.7 33.4 1999.2 49.2 57.2 21.8 18.2 4686.1 23.5 21.6 23.3 52973.6 27.1 493.1 188.1 37.1 24979.9 41.7 45.6 43.4 88.0 40.9 42.7 47.7 44.8 50.7 44.2 45.5 46.2 1.1 224.4 489.8 0.0 77.2 19.6 3.5 4126.5 50.7 0.0 13.2 3.9 10.0 70.1 817.0 14.7 0.0 5.8 67.1 0.3 0.0 1.0 210.7 0.5 0.6 33.1 0.0 143.5 0.0 0.9 8.5 61.3 1.1 0.5 227.1 0.1 76.1 54.6 417.5 0.0 0.0 0.2 207.5 6348.0 5.1 172.4 4.1 3758.3 0.0 0.0 6932.6 0.0 289.4 0.0 0.0 1.4 0.0 1.5 26.1 0.9 0.0 25.0 162.8 0.0 0.0 7.7 32.3 2.1 1.0 8480.1 113.2 6.7 91.4 0.0 0.0 31.3 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 1410.7;stomach 1: 1742.0;urinary bladder: 1777.0" "Cell type enhanced" "Detected in many" "Club cells: 1088.3;Gastric mucus-secreting cells: 2306.9;Syncytiotrophoblasts: 2773.6;Urothelial cells: 4448.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 564.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 46 "basophil: 1789.3;eosinophil: 836.9;neutrophil: 2961.8" "Lineage enriched" "Detected in many" 73 "granulocytes: 2961.8" "Cell line enhanced" "Detected in many" "BEWO: 879.0;Hep G2: 1283.2;hTCEpi: 1185.6;OE19: 4335.4;RT4: 2619.8;SK-BR-3: 1057.4" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA019502: AB_1856530, HPA075251: " "unprognostic (1.46e-1)" "unprognostic (1.50e-1)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.22e-1)" "unprognostic (7.34e-2)" "unprognostic (1.60e-3)" "unprognostic (3.92e-2)" "unprognostic (7.19e-2)" "unprognostic (9.24e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (3.65e-1)" "unprognostic (1.12e-2)" 14.0 1.7 1.0 42.4 1.4 1410.7 7.4 1.6 6.3 15.0 1.4 155.6 13.2 5.9 0.0 340.6 6.9 52.1 2.7 1.4 0.9 2.1 8.8 14.7 1.0 1.1 1.1 0.5 4.7 0.4 1.7 474.7 3.2 25.5 176.0 0.1 8.2 0.5 0.4 20.9 23.8 16.6 0.6 34.3 1742.0 1.4 1.0 10.6 0.6 12.2 96.9 1777.0 34.5 1.1 115.2 89.1 0.0 0.1 0.0 0.5 879.0 0.0 1.0 0.0 0.0 5.2 17.6 0.7 40.1 0.6 1.2 137.6 0.5 1.1 0.0 54.7 0.0 1.9 106.7 1283.2 0.0 53.4 3.2 0.6 1185.6 0.0 1.1 0.2 0.2 0.8 3.1 0.0 0.0 214.5 1.6 126.5 1.5 4335.4 149.6 0.9 0.5 0.5 0.0 2619.8 1.1 0.7 156.8 1057.4 2.4 39.9 31.0 169.6 0.5 0.0 1.4 0.2 0.9 1.2 0.7 0.8 0.1 479.1 0.2 1789.3 40.6 836.9 1.4 9.5 1.1 0.4 1.7 1.1 1.6 0.5 0.3 0.8 2961.8 0.1 5.7 0.4 1.1 16.7 1.0 1.4 1.6 6.3 1.4 0.9 1.1 1.1 3.2 0.6 1.0 1.1 0.9 9.6 48.6 0.0 6.2 1.1 318.3 568.6 4.0 0.0 3.4 3.6 1.2 27.1 1088.3 1.8 0.0 550.7 2.2 322.2 0.0 4.8 12.3 37.5 38.9 8.7 16.6 0.0 0.0 31.1 783.4 13.8 2306.9 202.5 31.6 0.0 1.4 7.4 69.2 0.0 0.0 443.7 152.5 11.8 1.0 7.4 0.0 11.0 8.8 0.0 5.6 0.0 2.1 0.0 0.1 828.1 580.9 0.0 5.9 288.4 2.2 0.5 301.5 0.0 0.0 0.1 32.1 0.5 0.6 18.6 6.3 2773.6 9.8 0.1 173.2 4448.3 SAE1 "AOS1, FLJ3091, Sua1" ENSG00000142230 "SUMO1 activating enzyme subunit 1" Q9UBE0 19 47113274-47210636 "Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041906, HPA043552" Supported Enhanced Nucleoplasm,Cytosol NA NA 37000 "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cytosol" "HPA041906: AB_2677735, HPA043552: AB_2678548" "unprognostic (9.69e-3)" "unprognostic (1.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.49e-8)" "unprognostic (9.86e-2)" "unprognostic (1.62e-2)" "unprognostic (1.58e-1)" "unprognostic (1.93e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.15e-5)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (1.27e-1)" 43.9 34.7 33.1 18.7 33.9 21.5 38.9 30.2 39.9 47.8 29.7 115.7 9.9 58.5 4.9 53.0 44.5 14.7 44.3 34.2 34.3 29.4 32.4 39.5 23.1 33.4 33.5 36.4 29.3 22.1 27.2 21.6 33.4 38.5 15.8 11.0 31.0 22.3 53.6 41.3 43.2 27.6 30.5 51.8 59.1 76.6 35.6 36.5 50.8 17.7 24.9 68.1 42.3 34.4 126.7 71.6 189.2 81.8 57.9 68.8 51.3 180.7 130.3 154.7 192.7 76.0 61.6 131.4 72.6 112.0 89.6 49.4 179.6 93.2 141.0 138.4 172.0 117.4 45.2 62.7 68.4 142.3 81.7 64.0 42.2 75.4 72.0 58.9 142.2 141.3 138.7 51.3 135.9 68.0 127.1 396.8 87.3 116.0 68.5 171.7 110.2 47.9 56.2 77.1 59.9 79.3 126.8 87.9 79.3 84.3 70.8 75.9 72.7 71.0 103.8 47.0 161.9 97.0 352.1 206.5 44.7 108.7 98.5 55.3 37.6 21.7 41.6 34.7 45.2 37.2 50.4 43.2 45.2 29.6 69.9 54.6 18.9 63.8 23.6 30.1 69.4 65.3 33.1 33.9 30.2 39.9 34.2 34.3 33.4 33.5 33.4 30.5 35.6 34.4 29.2 9.6 18.7 11.4 24.1 25.6 32.6 33.2 16.5 20.1 19.2 16.3 21.9 15.7 18.6 12.9 6.2 77.7 20.5 18.5 11.7 41.6 13.1 13.3 34.4 39.4 19.2 36.6 20.9 34.9 107.2 30.8 17.3 22.0 15.2 40.2 22.1 21.0 57.6 20.2 21.8 25.2 42.7 17.2 25.0 19.1 15.5 19.2 46.2 10.3 48.5 25.8 41.2 10.6 16.3 38.1 20.1 18.8 26.3 32.6 11.4 15.6 7.2 16.6 52.6 16.5 39.0 151.3 113.7 22.4 24.6 57.5 33.5 35.4 32.5 30.5 SAMD12 FLJ39458 ENSG00000177570 "Sterile alpha motif domain containing 12" Q8N8I0 8 118189455-118622112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 537.6;Inhibitory neurons: 531.7;Oligodendrocytes: 1158.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 34.6;U-266/70: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024634 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA024634: AB_1856549" "unprognostic (6.96e-2)" "unprognostic (9.35e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (4.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.99e-2)" "unprognostic (1.68e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-1)" "prognostic favorable (1.52e-6)" "unprognostic (3.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (6.35e-3)" 0.7 1.4 2.4 1.1 4.9 0.4 3.0 0.7 8.8 2.3 0.0 4.0 3.7 1.1 4.0 4.1 5.3 3.6 6.9 7.5 0.8 5.2 1.6 4.2 0.7 1.4 0.5 0.9 1.9 9.6 3.3 0.1 2.6 3.7 4.7 5.9 2.4 5.0 0.8 0.8 2.0 0.7 0.9 2.6 5.7 1.3 2.1 1.0 10.2 0.1 2.0 4.4 1.1 8.4 10.2 0.7 0.9 0.0 0.0 0.0 2.1 3.4 10.4 7.8 4.3 1.1 12.1 3.4 0.8 8.2 1.6 1.9 2.0 4.7 11.9 0.1 1.1 0.0 5.7 0.0 0.0 0.0 0.2 0.0 2.3 4.6 0.4 2.8 0.2 5.9 0.0 6.0 6.0 2.0 1.6 0.0 0.8 13.2 1.3 0.0 0.0 9.7 5.4 13.5 4.0 0.0 2.8 34.6 0.0 2.1 0.5 0.0 0.0 0.1 3.8 1.4 1.2 14.9 10.2 0.4 1.8 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.0 1.5 0.8 0.5 0.0 1.0 1.0 0.6 0.1 0.6 0.0 0.3 0.8 0.2 2.4 4.9 0.7 8.8 7.5 0.8 1.4 0.5 2.6 0.9 2.1 8.4 4.7 112.2 95.0 53.5 8.0 1.7 10.1 10.3 13.1 16.8 10.9 5.1 12.1 12.8 57.5 29.5 43.8 0.0 3.3 10.5 19.6 12.9 5.2 12.1 1.5 13.0 14.3 2.1 537.6 12.4 0.1 9.1 26.5 16.4 56.8 4.4 7.5 5.2 0.1 30.3 531.7 11.2 14.2 0.3 0.0 6.1 0.3 6.5 7.2 163.0 0.7 4.5 4.1 122.6 1158.0 13.0 3.5 0.4 16.9 5.0 8.6 17.4 68.0 26.9 0.0 0.5 0.9 0.5 2.4 15.9 1.7 0.0 8.9 4.5 11.9 13.6 SAMD3 "bA73O6.2, FLJ34032" ENSG00000164483 "Sterile alpha motif domain containing 3" Q8N6K7 6 130144315-130365425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Cell type enhanced" "Detected in many" "dendritic cells: 157.0;NK-cells: 271.9;Plasma cells: 43.7;T-cells: 84.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 47 "NK-cells: 128.4;T-cells: 113.8" "Cell line enhanced" "Detected in some" "HBF TERT88: 1.8;HDLM-2: 3.4;hTEC/SVTERT24-B: 2.2;hTERT-RPE1: 1.9;NTERA-2: 1.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 2.1" "HPA028992, HPA028993" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA028992: AB_10598914, HPA028993: AB_10601891" "unprognostic (2.91e-3)" "unprognostic (5.35e-3)" "unprognostic (4.15e-2)" "unprognostic (2.70e-2)" "unprognostic (1.50e-2)" "unprognostic (2.48e-4)" "unprognostic (1.20e-2)" "unprognostic (2.42e-3)" "unprognostic (2.39e-2)" "unprognostic (2.46e-2)" "unprognostic (5.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.07e-6)" "unprognostic (7.09e-2)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (3.45e-2)" 1.1 2.3 1.4 4.0 2.0 4.2 0.9 0.6 1.6 2.9 0.6 1.2 0.7 4.4 1.9 0.7 1.5 2.3 0.5 2.9 1.2 1.1 1.7 3.3 10.4 0.8 2.0 1.8 1.2 0.1 4.8 0.7 0.9 0.7 2.3 1.4 0.7 0.4 0.8 0.5 1.4 1.7 0.4 9.3 1.6 3.2 1.9 6.3 0.8 0.7 4.2 1.3 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.3 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.8 3.4 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.3 0.0 2.2 0.1 1.9 0.2 0.4 0.1 0.0 0.2 0.0 0.1 0.0 1.7 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.5 113.8 0.4 90.0 2.5 39.8 102.1 0.6 0.3 28.8 68.9 2.3 128.4 0.6 0.6 41.7 41.4 1.4 2.0 0.6 1.6 2.9 1.2 0.8 2.0 0.9 0.4 1.9 0.4 1.1 0.0 2.3 1.3 2.3 0.4 0.0 0.0 0.6 3.0 0.6 0.5 0.8 0.0 0.0 0.0 0.0 0.0 157.0 1.6 0.0 0.2 25.4 1.0 2.1 0.8 3.6 6.6 12.1 0.0 0.0 0.7 0.0 0.5 1.3 14.8 2.9 0.4 0.0 0.0 5.7 0.3 0.0 3.4 1.4 6.7 0.6 1.8 5.4 12.2 2.3 0.0 271.9 1.5 0.6 0.0 1.5 1.9 43.7 0.0 0.1 0.6 0.7 0.4 0.0 0.3 1.4 2.3 1.6 0.2 0.4 0.0 84.3 2.0 0.5 0.1 SAP18 "2HOR0202, MGC27131, SAP18p" ENSG00000150459 "Sin3A associated protein 18" O00422 13 21140514-21149084 "Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011352, CAB012273" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nuclear bodies" Cytosol "CAB012273: , HPA011352: AB_1856563" "unprognostic (5.08e-2)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-3)" "unprognostic (2.84e-1)" "unprognostic (5.21e-2)" "unprognostic (3.02e-1)" "unprognostic (3.18e-1)" "unprognostic (8.15e-2)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (4.14e-2)" "unprognostic (2.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.70e-2)" "unprognostic (3.70e-3)" "unprognostic (2.78e-2)" 125.7 164.3 140.9 122.9 152.2 242.3 121.6 149.6 198.9 120.4 137.8 141.8 137.4 123.8 97.5 159.2 112.9 82.4 195.8 147.4 160.7 190.4 171.1 106.5 118.0 154.7 153.8 109.5 134.6 114.2 129.6 111.7 157.7 109.7 58.5 89.5 126.3 73.0 297.9 119.5 127.5 51.7 164.1 107.6 119.5 194.3 155.7 115.5 110.7 156.3 64.8 131.7 118.5 170.7 182.1 99.3 159.5 173.1 169.0 140.5 246.9 227.1 167.2 205.5 151.3 181.1 342.4 187.3 272.0 189.1 223.4 186.5 198.1 142.4 231.5 288.0 100.4 267.6 121.2 305.9 191.8 367.1 207.5 143.0 159.7 157.5 187.1 158.4 157.3 223.1 128.8 103.6 188.2 231.0 417.0 599.0 200.7 501.5 109.7 261.1 251.4 187.1 295.7 160.7 185.0 161.1 145.7 213.8 296.5 176.5 206.8 528.0 192.6 126.0 141.9 230.1 268.9 159.6 243.6 536.7 122.5 214.9 236.4 433.0 431.5 540.0 344.1 485.0 349.3 493.7 418.2 410.9 427.8 443.6 405.9 402.9 430.5 395.3 547.4 568.8 517.5 909.3 140.9 152.2 149.6 198.9 147.4 160.7 154.7 153.8 157.7 164.1 155.7 170.7 638.0 134.6 143.5 15.0 291.7 458.6 336.3 640.9 310.7 101.5 298.9 594.9 592.9 194.5 383.8 233.6 41.7 566.2 397.4 353.6 759.2 396.5 1259.5 334.1 231.1 273.1 234.5 214.4 20.8 365.6 528.0 374.0 170.2 256.2 258.6 176.6 180.2 242.0 396.0 119.5 23.4 364.5 468.0 189.5 440.9 206.0 342.3 260.4 407.4 17.8 385.0 370.8 233.8 19.6 26.2 401.9 417.6 303.6 182.3 325.9 475.0 1100.6 446.8 132.3 203.8 362.5 438.3 547.7 319.9 271.7 422.2 908.3 338.8 254.2 344.7 419.9 SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "Rods & Rings" "HPA040400: AB_2676962" "unprognostic (1.11e-1)" "unprognostic (4.78e-2)" "unprognostic (4.27e-3)" "unprognostic (1.38e-3)" "unprognostic (7.86e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (8.03e-2)" "unprognostic (6.70e-3)" "unprognostic (1.06e-2)" "unprognostic (5.09e-2)" "unprognostic (3.88e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-1)" 139.9 294.5 208.6 169.1 228.0 253.0 169.9 187.2 246.6 153.8 196.2 143.0 123.9 152.1 408.6 91.0 205.9 182.1 151.8 234.6 308.8 205.2 302.3 167.5 218.9 214.0 258.8 255.7 231.4 236.5 138.9 309.2 247.6 228.2 143.5 219.1 212.9 172.7 111.1 70.8 140.5 139.1 219.5 159.0 161.1 104.3 290.5 243.4 245.4 129.0 186.5 141.0 64.0 218.5 119.9 112.4 147.9 79.9 209.3 149.8 69.7 139.2 247.0 128.5 173.7 72.2 139.9 80.9 183.5 156.0 134.7 97.7 100.8 112.4 146.9 33.6 49.5 112.2 87.3 119.2 189.6 48.8 130.6 175.2 260.0 121.6 125.5 257.4 192.0 150.7 128.4 191.2 142.9 74.2 128.4 88.8 96.0 253.6 61.3 98.7 88.4 107.4 220.3 100.4 48.6 162.5 140.6 160.5 208.2 115.7 112.2 93.3 144.0 89.6 230.5 35.0 56.5 103.4 110.6 81.0 215.8 118.4 146.5 964.6 252.9 443.1 321.2 253.2 364.8 233.1 473.0 377.9 247.0 302.4 776.2 543.6 478.1 258.8 335.3 212.0 483.8 920.3 208.6 228.0 187.2 246.6 234.6 308.8 214.0 258.8 247.6 219.5 290.5 218.5 179.8 169.9 147.6 79.0 458.5 0.0 331.6 0.0 154.8 291.5 247.8 166.2 135.4 261.7 82.3 211.5 123.0 235.9 566.8 142.2 127.2 387.5 629.8 235.9 114.8 170.8 115.3 145.4 128.0 358.9 254.5 181.7 170.7 133.6 223.3 325.7 240.2 273.4 292.0 139.7 157.8 122.0 0.0 448.6 0.0 908.1 218.7 387.9 0.0 60.9 298.5 317.2 358.4 82.9 111.7 250.1 137.0 294.2 505.1 280.7 252.6 289.7 212.1 252.5 177.5 203.7 177.1 194.7 133.9 133.4 0.0 276.9 794.4 167.8 115.9 310.6 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCD5 "ACOD4, FADS4, FLJ21032, HSCD5, SCD4" ENSG00000145284 "Stearoyl-CoA desaturase 5" Q86SK9 4 82629539-82798796 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.7;brain: 353.6" "Cell type enhanced" "Detected in many" "Astrocytes: 248.4;Oligodendrocyte precursor cells: 892.7;Oligodendrocytes: 513.6" "Group enriched" "Detected in all" 6 "glioma: 152.4;thyroid cancer: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 69.2;RPTEC TERT1: 90.1" "Low region specificity" "Detected in all" HPA042380 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" "HPA042380: AB_10794797" "unprognostic (3.23e-2)" "unprognostic (3.84e-2)" "unprognostic (2.86e-1)" "unprognostic (6.98e-2)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (3.82e-2)" "unprognostic (6.82e-2)" "unprognostic (3.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "prognostic favorable (2.32e-5)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.88e-3)" "unprognostic (2.92e-2)" 6.8 156.7 226.1 3.7 283.7 2.9 5.7 302.5 260.4 10.6 85.2 12.9 4.5 12.5 97.6 5.8 18.7 9.3 8.1 212.6 277.4 33.1 2.5 15.0 3.0 353.6 272.7 93.7 40.9 18.7 31.4 7.5 291.0 12.7 4.0 70.2 18.0 24.3 1.3 8.2 6.0 12.0 314.1 4.5 10.6 33.3 255.6 10.6 35.5 4.2 4.4 7.7 8.7 316.2 11.2 7.1 36.0 18.6 19.7 12.5 0.6 69.2 33.9 29.7 22.8 0.5 1.7 22.5 23.5 14.5 8.0 19.9 10.6 7.6 37.0 4.4 4.7 1.0 8.1 0.7 2.9 10.0 6.9 10.0 30.6 5.9 5.2 30.5 48.4 25.8 1.3 2.2 15.6 4.4 42.6 2.1 2.6 0.2 5.0 35.6 21.5 17.9 90.1 11.2 20.1 11.5 11.4 0.5 6.8 3.5 1.3 5.0 59.5 31.5 18.1 11.9 18.9 6.0 2.5 2.2 15.3 10.5 9.0 1.9 0.6 0.1 3.9 0.2 2.5 0.2 0.8 2.3 0.3 0.4 0.7 2.6 0.7 1.1 0.4 0.7 0.2 1.2 226.1 283.7 302.5 260.4 212.6 277.4 353.6 272.7 291.0 314.1 255.6 316.2 1.4 44.8 3.9 248.4 0.8 10.7 16.5 16.3 5.7 101.4 6.8 4.8 2.9 27.1 25.7 27.6 25.0 1.9 3.9 0.4 13.7 79.7 115.0 13.5 9.3 7.7 7.7 0.0 84.3 46.9 0.2 16.8 2.6 14.8 0.0 10.5 10.4 0.2 1.1 101.0 107.0 0.3 10.2 1.3 3.3 100.3 55.0 1.8 3.6 23.4 1.9 145.3 4.1 892.7 513.6 8.9 0.0 58.3 0.7 11.3 0.2 20.4 13.0 14.6 6.6 3.6 11.5 2.9 3.7 2.7 7.2 0.1 3.2 137.4 2.0 9.3 SCFD1 "C14orf163, KIAA0917, RA410, SLY1, STXBP1L2" ENSG00000092108 "Sec1 family domain containing 1" Q8WVM8 14 30622291-30737694 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003579 Approved NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA003579: AB_1079872" "unprognostic (2.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.24e-2)" "unprognostic (1.21e-1)" "unprognostic (3.21e-2)" "unprognostic (3.07e-2)" "unprognostic (8.35e-2)" "unprognostic (2.65e-1)" "unprognostic (7.52e-3)" "unprognostic (1.05e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-1)" "unprognostic (6.32e-2)" 23.2 29.3 11.8 22.3 12.4 9.9 29.2 12.3 12.6 34.0 13.0 27.6 22.2 21.8 40.8 29.7 21.7 19.6 29.6 11.9 12.4 32.5 35.1 22.5 26.2 11.8 12.1 23.6 46.4 41.8 29.3 27.8 11.8 27.7 29.8 14.9 52.3 24.0 24.6 19.5 23.8 22.9 11.5 19.0 28.0 26.6 11.6 25.6 44.3 29.3 29.1 30.0 20.8 12.0 71.7 26.0 37.8 22.9 64.1 67.0 53.4 57.0 68.4 69.5 83.5 42.2 58.9 36.9 24.2 79.7 38.8 44.5 41.3 46.5 80.0 53.2 22.2 30.7 28.6 149.5 77.9 50.2 32.4 49.1 39.1 48.9 78.1 58.5 45.5 26.5 42.6 68.0 74.7 66.8 30.7 27.8 40.7 83.9 45.1 30.2 42.1 42.2 70.7 45.6 35.9 33.0 58.7 54.4 53.6 42.9 70.5 35.3 48.1 41.9 44.0 43.0 45.3 45.3 40.8 49.4 26.9 36.7 52.9 26.8 17.2 20.2 14.0 23.2 17.8 20.1 16.2 17.3 23.7 14.7 15.2 14.1 3.0 23.1 27.8 16.9 24.4 16.1 11.8 12.4 12.3 12.6 11.9 12.4 11.8 12.1 11.8 11.5 11.6 12.0 33.0 51.3 31.3 67.9 47.7 25.0 55.2 55.1 18.2 35.0 26.9 27.1 35.3 18.6 50.8 25.8 43.8 61.9 51.3 31.8 64.6 49.2 29.3 34.9 51.6 32.3 47.2 24.2 123.0 50.6 61.0 47.9 20.9 34.2 53.7 32.1 24.3 20.6 44.9 30.3 112.8 44.9 36.7 27.7 33.4 16.6 38.5 35.5 37.4 90.9 66.9 31.1 62.8 112.6 106.6 41.2 23.5 40.3 70.9 42.3 28.8 40.9 52.1 39.9 13.1 53.7 49.0 71.8 53.5 20.5 24.4 83.0 41.4 47.8 30.0 43.5 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 212.4;Enteroendocrine cells: 283.4;Inhibitory neurons: 109.9;Ionocytes: 138.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.3;HSkMC: 45.9;hTERT-RPE1: 46.5;SCLC-21H: 47.6;SH-SY5Y: 20.7;WM-115: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 9.2 360.1 49.2 30.2 78.4 0.4 0.5 17.1 54.7 1.5 2.2 10.6 47.7 3.5 0.4 0.6 0.2 4.0 1.7 21.7 426.2 0.6 0.2 3.3 0.4 118.3 195.4 6.1 28.3 0.5 269.0 1.1 250.9 3.5 13.0 40.6 0.3 1.2 0.3 1.0 21.3 12.8 77.4 0.2 17.9 0.2 130.7 0.1 6.4 0.8 0.1 0.8 1.3 30.3 0.0 3.1 10.3 8.5 2.3 53.3 0.2 0.5 2.0 4.0 10.1 0.4 1.0 0.0 0.9 0.7 6.2 0.2 0.2 0.0 5.0 0.1 0.5 0.0 0.6 0.0 0.5 0.7 4.6 45.9 0.2 5.8 2.0 46.5 0.0 0.0 0.2 0.4 5.1 0.3 0.0 0.2 7.3 0.1 0.2 0.0 0.3 0.3 0.9 0.1 47.6 20.7 0.0 0.5 2.5 1.6 0.0 0.1 0.1 5.4 2.2 0.2 3.6 0.1 0.0 0.3 1.6 0.1 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 78.4 17.1 54.7 21.7 426.2 118.3 195.4 250.9 77.4 130.7 30.3 0.0 6.4 0.0 12.7 0.0 0.0 0.4 2.8 0.0 212.4 0.0 0.0 0.1 0.0 1.3 0.0 2.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 6.7 283.4 0.0 27.7 0.2 0.0 2.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 8.4 109.9 14.7 138.4 0.3 0.3 0.0 0.6 0.0 1.8 3.7 0.0 11.6 0.0 34.2 8.2 14.8 6.2 0.4 0.0 2.1 0.1 0.1 0.7 14.6 0.0 1.8 1.7 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.5 0.8 SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 157.3" "Cell type enhanced" "Detected in many" "Collecting duct cells: 114.0;Distal enterocytes: 230.9;Glandular and luminal cells: 189.8;Intestinal goblet cells: 180.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 6.8" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 300.5;HBEC3-KT: 202.4;hTCEpi: 85.3;RPTEC TERT1: 103.7;RT4: 114.1;SK-BR-3: 96.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA012743 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "HPA012743: AB_1856627" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.62e-1)" "unprognostic (2.19e-1)" "unprognostic (5.16e-2)" "unprognostic (6.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.62e-2)" "unprognostic (5.13e-2)" "prognostic unfavorable (8.86e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (5.56e-2)" "prognostic favorable (9.21e-8)" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" 3.4 12.5 0.2 5.6 0.1 0.5 20.6 1.1 0.2 64.7 113.6 66.4 18.7 7.6 43.2 140.1 57.9 17.7 0.7 6.8 0.0 148.5 8.2 62.9 0.2 0.1 0.3 3.5 40.0 0.7 16.6 0.4 0.1 43.7 65.4 0.0 157.3 49.5 0.5 54.6 26.0 2.9 0.1 0.7 63.6 4.7 1.3 1.9 94.3 0.1 12.5 20.8 57.6 0.1 21.6 4.1 0.0 1.9 0.3 0.4 17.6 0.0 0.1 0.1 0.0 6.1 300.5 0.3 0.8 0.1 0.1 14.0 0.0 202.4 0.0 0.0 0.0 0.0 17.5 3.1 20.9 0.0 0.1 5.1 85.3 0.0 61.6 0.4 0.0 0.5 0.0 0.1 0.5 1.9 0.1 0.3 17.6 38.9 0.8 0.2 0.0 0.5 103.7 114.1 1.2 0.1 2.3 96.7 0.1 17.1 22.3 0.0 0.0 0.2 0.7 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 1.5 0.0 0.0 1.0 0.5 0.1 0.2 0.1 1.1 0.2 6.8 0.0 0.1 0.3 0.1 0.1 1.3 0.1 1.7 73.7 75.7 0.0 1.3 1.9 25.1 17.0 10.8 0.9 17.7 21.2 0.8 54.3 52.5 114.0 4.2 1.4 1.8 230.9 5.9 45.0 0.5 85.3 17.8 3.2 27.1 0.0 0.3 33.9 0.3 2.0 97.3 189.8 2.5 1.3 1.4 3.2 0.3 1.7 0.2 180.3 63.1 1.9 3.1 0.6 1.8 2.5 0.0 0.0 1.6 0.3 1.0 0.5 0.1 39.4 95.8 1.5 0.3 30.9 12.2 6.2 36.7 1.4 0.0 5.6 4.3 1.2 3.7 48.1 8.8 1.6 3.6 0.2 31.5 42.1 SCOC "HRIHFB2072, SCOCO, UNC-69" ENSG00000153130 "Short coiled-coil protein" Q9UIL1 4 140257286-140385728 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 320.8;Early spermatids: 537.1;Proximal tubular cells: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061198, HPA070321" Approved Approved "Nucleoplasm,Golgi apparatus" NA NA 22000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA061198: AB_2684449, HPA070321: AB_2686252" "unprognostic (2.27e-2)" "unprognostic (2.26e-2)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (7.34e-3)" "unprognostic (1.37e-3)" "unprognostic (8.99e-3)" "unprognostic (1.13e-1)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.30e-1)" "unprognostic (4.03e-1)" "prognostic favorable (4.82e-12)" "unprognostic (2.98e-2)" "unprognostic (1.32e-1)" "unprognostic (7.51e-2)" "unprognostic (1.28e-2)" 44.8 66.8 81.8 27.7 84.5 14.7 69.4 87.4 114.6 42.6 72.0 43.9 45.4 48.0 79.5 54.1 44.7 39.7 103.6 85.1 109.1 101.6 74.3 35.9 29.7 91.3 96.8 42.6 51.3 94.1 43.2 48.3 103.1 59.9 49.8 74.5 49.2 47.1 40.8 29.9 37.1 50.9 91.4 27.9 53.7 33.8 95.2 29.3 67.4 59.3 32.8 38.9 19.4 105.6 53.9 38.1 92.6 49.9 80.6 109.3 67.4 85.5 78.0 64.6 71.8 24.4 81.0 22.0 75.5 83.9 60.6 22.6 57.3 113.6 95.7 79.1 40.4 33.5 18.8 59.7 70.1 70.2 40.5 72.5 155.9 59.0 63.1 124.1 87.1 63.8 53.0 60.0 116.3 36.5 94.7 42.5 30.2 47.6 57.1 54.0 39.1 32.1 197.1 52.9 68.4 70.4 57.0 84.5 97.0 81.7 63.4 41.9 68.0 104.4 60.5 86.9 83.1 94.4 193.4 64.9 118.2 32.2 102.3 47.8 16.5 23.0 27.5 23.0 35.1 36.8 32.3 27.3 21.4 30.3 46.8 36.4 9.7 36.9 23.1 26.7 33.2 37.0 81.8 84.5 87.4 114.6 85.1 109.1 91.3 96.8 103.1 91.4 95.2 105.6 63.2 48.1 47.2 15.3 34.4 61.1 69.7 74.1 78.6 135.0 84.9 96.0 140.3 62.9 51.8 126.9 22.9 139.9 31.3 63.4 320.8 99.2 537.1 67.5 52.4 54.4 37.8 34.7 33.8 112.8 82.2 58.3 66.8 58.4 36.8 32.0 51.4 65.0 47.6 171.6 37.1 42.7 114.0 23.0 27.9 91.2 60.0 34.5 138.7 17.8 36.7 205.6 22.6 20.6 42.9 92.9 37.0 66.2 30.8 91.7 46.8 311.1 54.9 71.0 46.0 40.8 64.5 60.7 56.1 83.8 56.7 88.9 36.3 39.6 46.1 56.0 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" 16.2 32.2 14.6 8.7 14.6 8.8 14.2 14.9 15.2 17.5 18.5 15.7 8.0 14.4 27.2 13.8 17.3 13.0 17.5 14.9 16.3 18.5 23.2 15.4 9.4 15.4 15.3 19.7 19.9 20.1 19.1 20.5 16.0 18.2 11.1 6.6 21.8 15.7 14.7 11.5 13.0 14.4 15.3 16.1 15.3 9.4 15.9 12.7 16.2 12.9 8.1 20.2 14.3 14.9 18.8 54.3 25.2 18.7 107.1 29.6 18.0 53.6 48.4 39.6 49.8 34.6 23.5 8.0 47.8 57.6 36.6 30.5 24.7 22.6 27.8 62.3 29.8 13.7 26.6 28.6 30.9 8.1 17.2 53.7 28.5 38.3 8.8 34.4 39.9 11.0 14.9 19.4 45.1 35.9 20.7 22.2 12.9 48.8 19.2 12.5 37.1 24.8 45.3 29.6 15.6 18.1 42.3 32.4 30.3 37.5 43.7 10.4 45.0 21.0 23.3 24.2 31.2 25.2 35.2 11.9 32.0 12.9 23.9 189.1 45.1 129.1 64.4 39.6 62.6 50.8 52.2 62.8 30.0 44.4 47.1 55.9 203.1 71.1 42.1 62.5 74.2 59.7 14.6 14.6 14.9 15.2 14.9 16.3 15.4 15.3 16.0 15.3 15.9 14.9 61.1 25.6 21.7 10.4 45.5 34.0 59.1 125.6 41.5 26.4 49.4 44.6 13.1 38.6 71.1 42.3 25.0 130.3 74.0 82.8 29.4 74.8 7.4 36.2 43.6 52.2 57.1 37.5 11.1 47.2 109.0 52.6 27.5 44.9 21.0 47.2 53.2 46.2 56.7 13.5 12.2 57.5 71.2 44.9 49.7 3.9 76.1 38.1 37.4 8.4 50.2 49.9 56.7 11.1 17.8 80.4 90.4 66.5 46.2 54.1 88.0 50.7 47.8 31.1 72.3 36.7 48.1 30.5 32.1 40.6 37.6 211.0 53.2 86.0 46.2 86.9 SDHD "cybS, PGL, PGL1" ENSG00000204370 "Succinate dehydrogenase complex subunit D" O14521 11 112086824-112120016 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 530.2;Proximal tubular cells: 449.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045727 Approved "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "HPA045727: AB_10963114" "unprognostic (9.13e-2)" "unprognostic (3.51e-2)" "unprognostic (4.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.93e-1)" "unprognostic (4.98e-2)" "unprognostic (5.69e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-3)" "unprognostic (7.10e-2)" "unprognostic (3.03e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.99e-10)" "unprognostic (5.14e-2)" "unprognostic (1.58e-2)" "unprognostic (1.56e-2)" "unprognostic (7.51e-2)" 117.5 95.7 60.0 84.5 63.1 72.9 102.6 68.6 76.3 92.5 65.1 185.2 208.1 88.2 96.7 126.7 92.6 85.6 254.7 60.1 65.4 319.9 391.8 79.3 131.7 63.4 62.5 91.6 77.8 152.4 37.0 95.0 63.2 87.9 190.8 37.4 112.6 100.9 354.7 64.3 175.6 98.1 64.7 85.1 101.1 34.1 63.7 102.5 136.8 449.6 124.8 117.9 76.4 68.2 84.0 67.3 58.1 89.4 212.0 170.7 97.3 97.5 147.6 106.8 132.2 244.8 222.1 155.5 288.4 131.0 156.1 203.5 175.4 139.8 129.8 129.9 92.4 142.8 51.9 140.1 165.6 222.4 107.5 189.6 160.2 110.5 189.1 124.6 153.0 109.6 156.0 208.7 135.0 95.2 143.9 215.0 77.4 333.8 211.6 126.2 145.8 294.4 221.6 175.2 83.5 55.8 135.3 194.8 107.0 81.8 198.9 164.2 108.0 103.8 132.3 114.7 95.0 59.1 73.2 270.7 58.8 297.0 100.5 233.7 293.3 208.8 158.4 390.1 173.1 235.2 170.8 168.8 308.7 198.1 204.3 191.8 257.5 207.9 322.9 151.7 189.9 348.9 60.0 63.1 68.6 76.3 60.1 65.4 63.4 62.5 63.2 64.7 63.7 68.2 104.3 80.1 51.1 12.4 78.0 81.6 102.2 262.2 83.6 12.2 61.0 78.4 216.5 120.1 108.1 90.1 8.4 154.3 55.2 203.8 530.2 82.9 9.9 41.6 67.6 76.4 50.4 70.2 9.6 58.9 124.1 104.6 75.4 41.2 65.9 32.3 76.8 169.7 162.9 11.8 11.2 129.1 154.6 97.1 74.4 37.0 104.1 94.2 76.5 9.4 118.6 52.9 75.2 8.0 9.7 54.1 134.2 99.6 80.9 61.6 253.1 449.9 60.5 18.9 92.1 78.3 110.7 70.4 55.8 127.1 74.4 179.0 71.4 86.2 176.0 98.6 SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.6" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2;Hepatocytes: 116.7;Hofbauer cells: 95.7;monocytes: 103.1;Proximal tubular cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.8" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HMC-1: 51.4;MCF7: 90.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA005740 Approved Approved Cytosol NA NA 48000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA005740: AB_10601486" "unprognostic (1.34e-1)" "unprognostic (8.33e-2)" "unprognostic (3.62e-2)" "unprognostic (3.54e-2)" "unprognostic (2.24e-2)" "unprognostic (6.17e-3)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.22e-2)" "unprognostic (2.00e-2)" "prognostic favorable (8.58e-4)" "unprognostic (2.93e-1)" "prognostic favorable (3.09e-5)" "unprognostic (2.22e-2)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (7.33e-2)" 4.5 33.1 12.7 7.1 14.2 3.2 4.9 16.4 15.2 4.6 10.8 12.2 16.8 4.8 9.9 2.5 7.9 7.7 12.8 11.8 16.1 34.9 104.6 5.7 3.4 18.7 16.2 4.6 18.7 12.4 15.5 4.4 16.0 8.5 8.5 2.4 4.8 6.6 3.0 1.3 12.2 5.2 15.8 5.8 9.1 10.6 16.4 1.5 23.9 1.3 1.7 6.2 1.4 17.4 8.5 33.3 4.7 14.1 0.9 1.9 3.2 4.8 1.2 5.2 4.4 14.1 8.7 0.4 24.2 8.1 14.4 8.6 2.2 11.4 1.7 20.5 8.4 22.1 8.5 6.3 27.5 2.8 51.4 4.4 16.0 12.8 18.8 5.9 8.0 0.0 17.3 6.6 6.5 90.2 0.1 10.2 4.6 9.6 14.6 0.0 7.0 16.5 13.6 10.6 1.5 0.5 20.6 23.6 18.4 4.2 28.6 24.8 7.2 6.2 11.9 26.9 4.2 1.4 1.4 0.3 26.3 8.4 7.8 0.2 8.7 0.0 0.0 10.0 0.0 2.2 0.0 0.0 18.5 0.1 0.0 0.0 0.4 1.8 1.3 17.8 0.3 2.5 12.7 14.2 16.4 15.2 11.8 16.1 18.7 16.2 16.0 15.8 16.4 17.4 1.2 0.0 5.1 2.0 3.1 0.9 2.2 7.0 0.0 0.5 15.3 10.2 18.2 27.1 6.3 29.5 2.1 16.3 4.9 43.7 78.2 36.1 0.5 14.8 7.7 4.0 31.8 10.1 1.3 20.1 3.0 4.5 12.8 10.1 43.8 15.3 6.4 116.7 95.7 3.3 0.6 36.4 4.1 18.1 8.4 1.5 2.8 36.9 3.6 1.9 103.1 33.5 0.0 1.5 2.0 16.2 63.2 5.7 0.0 6.1 63.2 115.7 3.8 2.6 0.0 0.2 7.3 0.2 0.4 1.1 0.6 7.3 1.9 29.5 31.0 5.9 SEC62 "Dtrp1, HTP1, TLOC1" ENSG00000008952 "SEC62 homolog, preprotein translocation factor" Q99442 3 169966635-169998373 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014059, HPA061450" Approved Approved "Endoplasmic reticulum,Intermediate filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Endoplasmic reticulum" "Intermediate filaments" "HPA014059: AB_1858029, HPA061450: AB_2684524" "unprognostic (8.15e-2)" "unprognostic (6.84e-2)" "unprognostic (2.72e-1)" "unprognostic (4.93e-3)" "unprognostic (5.13e-1)" "unprognostic (1.10e-3)" "unprognostic (1.24e-1)" "unprognostic (4.04e-1)" "unprognostic (6.78e-2)" "unprognostic (5.97e-2)" "unprognostic (6.36e-2)" "unprognostic (3.15e-1)" "unprognostic (2.83e-2)" "unprognostic (4.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" 104.9 86.5 82.9 58.6 94.3 94.4 64.5 88.1 120.6 74.4 74.6 60.9 58.5 74.7 131.9 44.4 52.3 58.5 49.1 81.8 108.1 118.6 193.7 67.6 63.3 94.9 97.7 75.9 116.5 109.7 41.5 71.0 97.9 82.5 56.6 128.9 130.4 83.5 55.3 27.4 59.4 68.3 95.5 83.5 91.1 34.6 92.3 51.1 120.9 60.2 67.0 63.7 31.7 99.9 140.4 96.6 74.2 66.3 217.9 114.7 46.7 175.5 128.3 80.0 82.5 104.0 143.9 156.8 190.7 125.9 132.5 130.3 92.3 84.8 124.7 123.1 89.2 108.6 57.2 105.6 157.9 111.6 68.5 115.0 79.7 88.0 85.3 108.8 80.1 47.3 68.0 147.2 96.3 117.2 58.9 59.0 76.4 110.8 62.5 77.6 107.6 212.8 115.1 88.5 76.1 71.9 143.7 155.8 125.3 71.3 233.5 101.0 107.8 113.1 51.0 95.6 143.1 168.8 134.9 240.8 118.5 85.1 108.0 17.2 34.8 62.3 44.2 37.1 49.2 77.6 40.6 43.5 30.9 82.1 50.9 46.6 52.0 31.8 29.0 35.1 39.1 27.6 82.9 94.3 88.1 120.6 81.8 108.1 94.9 97.7 97.9 95.5 92.3 99.9 419.0 237.2 291.5 64.6 362.7 254.4 252.8 511.1 144.0 362.0 223.3 278.5 582.1 320.3 431.7 680.5 277.3 218.7 209.5 144.7 195.6 256.4 31.6 302.9 424.8 363.7 261.1 874.1 79.3 347.6 215.0 396.3 104.5 455.3 293.5 105.2 463.7 1081.6 214.7 452.6 86.8 285.4 364.2 237.2 268.0 43.4 560.1 208.4 279.3 48.7 280.0 486.8 183.4 47.3 103.1 283.4 217.4 435.6 469.8 223.5 233.7 416.9 385.8 418.4 295.9 358.9 423.4 206.5 142.2 90.2 172.3 434.1 205.5 175.9 182.2 176.8 SEC63 "DNAJC23, ERdj2, PRO2507, SEC63L" ENSG00000025796 "SEC63 homolog, protein translocation regulator" Q9UGP8 6 107867756-107958208 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Protein transport, Transport" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Theca cells: 354.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053295, HPA060535" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA053295: AB_2682105, HPA060535: AB_2684312" "prognostic unfavorable (3.32e-4)" "prognostic unfavorable (4.01e-4)" "unprognostic (4.08e-1)" "unprognostic (1.56e-1)" "unprognostic (4.36e-3)" "unprognostic (1.51e-2)" "unprognostic (8.33e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (6.16e-4)" "unprognostic (2.35e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (4.41e-2)" 27.5 33.0 11.6 22.0 14.3 32.9 23.3 14.4 12.9 30.2 25.7 19.2 16.8 25.2 29.6 19.5 21.8 22.0 19.0 12.4 15.3 20.0 46.6 21.7 16.7 13.3 12.0 40.4 61.2 31.7 14.4 20.9 14.2 27.7 18.6 21.2 77.8 23.3 14.3 15.5 18.0 22.2 12.3 16.1 23.1 33.0 12.1 22.6 52.1 14.1 17.3 21.8 14.0 17.7 28.5 17.1 46.0 57.6 47.1 55.2 41.4 59.2 65.0 27.8 39.2 30.8 34.6 52.8 49.4 53.7 34.4 40.9 32.3 38.3 42.5 63.8 35.7 57.2 25.2 31.6 73.2 65.9 32.5 43.5 61.4 44.5 97.6 50.0 39.3 31.7 48.5 82.8 57.7 22.7 20.6 29.5 36.4 30.0 18.1 65.2 54.4 43.7 33.5 37.1 40.3 45.7 32.9 48.8 59.1 31.2 34.9 95.8 42.5 41.6 25.8 42.2 46.6 31.4 25.0 52.9 45.9 56.4 48.7 5.6 5.2 5.0 4.8 4.7 7.5 4.4 3.9 3.9 5.4 4.0 4.3 3.4 1.7 7.1 9.8 6.9 2.2 3.5 11.6 14.3 14.4 12.9 12.4 15.3 13.3 12.0 14.2 12.3 12.1 17.7 55.6 118.6 143.3 38.2 64.4 85.0 70.5 90.9 42.7 57.7 67.8 54.2 78.8 81.5 125.5 53.3 39.6 80.8 71.6 39.2 11.7 86.0 40.3 48.7 102.8 61.6 53.5 31.5 52.5 125.4 96.4 107.1 46.9 54.8 68.9 84.8 59.6 126.7 62.7 47.1 50.8 80.0 83.4 56.7 78.9 23.9 106.2 54.8 80.0 42.2 54.3 61.0 59.8 60.3 64.8 81.9 53.5 118.8 144.6 91.1 37.2 38.4 116.7 49.9 46.0 108.2 77.2 143.1 75.0 44.7 80.0 91.0 52.3 354.8 60.8 73.8 SEL1L "Hrd3, IBD2, SEL1L1" ENSG00000071537 "SEL1L adaptor subunit of ERAD E3 ubiquitin ligase" Q9UBV2 14 81471547-81533853 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "pancreas: 403.4" "Cell type enhanced" "Detected in all" "Plasma cells: 238.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 339.5;U-266/84: 313.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024267 Enhanced "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA024267: AB_1856659" "unprognostic (4.94e-1)" "unprognostic (8.69e-2)" "unprognostic (1.09e-2)" "unprognostic (1.91e-1)" "unprognostic (5.93e-2)" "unprognostic (1.16e-1)" "unprognostic (3.29e-1)" "unprognostic (2.78e-1)" "unprognostic (9.97e-2)" "unprognostic (2.58e-2)" "unprognostic (2.76e-3)" "unprognostic (4.86e-1)" "unprognostic (3.31e-2)" "unprognostic (1.30e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-2)" "unprognostic (1.25e-2)" 30.6 19.1 13.9 31.1 17.8 17.7 25.2 17.0 17.0 21.4 11.5 35.7 36.7 24.2 18.1 16.8 17.1 22.0 22.8 14.5 17.4 28.8 66.6 27.6 21.6 18.9 16.7 17.1 403.4 29.9 8.7 38.4 19.3 31.6 31.8 15.7 19.6 22.8 22.2 15.5 32.5 28.1 18.4 30.6 35.0 11.2 17.6 17.8 54.3 21.1 29.3 29.0 12.1 25.9 35.3 69.3 27.4 35.5 60.2 58.6 48.5 54.6 52.3 31.2 33.0 26.6 53.7 36.0 58.8 63.2 38.1 32.8 19.2 30.6 56.1 56.0 13.6 26.3 21.7 33.2 86.0 53.6 60.3 47.8 72.0 31.4 68.0 45.9 51.7 29.5 16.2 195.2 38.6 42.7 30.6 15.1 8.7 58.7 29.6 21.2 38.9 28.4 24.0 54.1 15.5 25.7 42.7 39.4 44.9 23.5 68.5 35.5 86.8 87.7 49.0 49.2 34.1 339.5 313.1 35.4 96.5 24.1 34.4 31.5 19.7 24.8 16.8 25.6 13.7 14.2 12.9 13.4 18.9 13.1 12.0 12.9 45.7 16.7 22.5 13.7 14.0 14.5 13.9 17.8 17.0 17.0 14.5 17.4 18.9 16.7 19.3 18.4 17.6 25.9 51.6 12.8 35.2 27.1 44.8 26.8 19.0 27.1 15.9 23.5 31.5 18.9 67.0 32.9 24.9 27.6 31.3 23.5 44.1 48.8 5.9 24.1 3.5 21.1 48.9 40.0 21.6 15.4 35.9 45.6 21.9 44.7 37.8 28.0 34.2 32.0 38.9 125.7 31.9 30.3 35.2 38.9 50.8 58.1 40.4 5.4 23.6 47.6 53.4 29.0 39.7 18.3 30.9 42.3 70.7 40.1 33.1 28.2 238.9 40.0 34.8 20.2 27.8 18.3 46.0 28.5 51.8 14.0 18.8 16.0 26.1 41.9 32.9 38.9 32.0 33.9 SELENOF SEP15 ENSG00000183291 "Selenoprotein F" O60613 1 86862445-86914424 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 248.6;Ductal cells: 235.9;Extravillous trophoblasts: 338.3;Hofbauer cells: 241.2;Syncytiotrophoblasts: 315.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054937 Approved Nucleoli,Cytosol "Intracellular and membrane" No No 420000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA054937: AB_2682642" "unprognostic (6.15e-2)" "unprognostic (6.98e-3)" "prognostic favorable (6.53e-4)" "unprognostic (6.20e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (8.17e-4)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.65e-1)" "unprognostic (6.51e-3)" "unprognostic (3.38e-2)" "unprognostic (3.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.79e-3)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (8.24e-3)" "unprognostic (1.34e-2)" 118.1 137.9 77.6 118.8 80.0 107.9 147.4 80.9 106.1 156.6 97.9 127.8 113.5 117.4 211.4 83.6 130.1 123.3 84.6 75.2 84.3 160.3 173.9 114.9 140.6 82.6 79.8 124.6 93.4 115.7 88.4 155.8 84.0 121.1 134.2 90.7 104.1 116.4 45.6 66.3 111.3 107.1 86.4 107.2 116.8 66.7 79.0 135.5 234.0 64.7 126.9 146.6 72.6 92.5 203.1 133.3 118.0 129.1 383.0 396.4 178.3 249.1 317.3 251.4 254.8 176.8 261.8 245.2 309.7 248.9 195.7 131.8 135.2 150.7 296.0 222.1 180.2 252.4 108.5 178.2 245.2 336.8 166.1 272.3 233.0 152.8 253.0 180.2 220.2 207.8 241.4 262.3 253.3 90.2 254.4 227.3 170.7 211.2 197.9 207.7 205.1 251.9 355.5 198.5 149.5 122.6 241.6 235.6 349.2 104.7 104.0 298.5 205.3 180.0 122.9 347.6 277.0 155.1 158.7 251.9 107.7 268.4 216.7 170.9 111.3 113.4 89.7 115.9 116.1 161.4 98.7 97.2 107.1 194.2 98.8 102.3 109.3 82.3 132.4 166.3 115.2 171.3 77.6 80.0 80.9 106.1 75.2 84.3 82.6 79.8 84.0 86.4 79.0 92.5 131.6 118.6 155.2 0.0 52.4 0.0 0.0 0.0 0.0 0.0 142.1 107.7 0.0 0.0 74.9 108.5 0.0 248.6 89.3 0.0 74.3 235.9 0.0 102.2 119.1 73.2 0.0 0.0 0.0 193.5 338.3 85.2 0.0 98.1 64.3 68.8 0.0 0.0 241.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.1 0.0 0.0 64.1 0.0 0.0 0.0 0.0 197.8 0.0 0.0 19.1 0.0 0.0 151.5 70.0 0.0 0.0 0.0 61.5 0.0 0.0 0.0 0.0 315.2 53.9 122.2 0.0 0.0 SELENOT SELT ENSG00000198843 "Selenoprotein T" P62341 3 150602875-150630445 "Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 215.1;Extravillous trophoblasts: 230.6;Hofbauer cells: 238.8;Pancreatic endocrine cells: 206.0;Proximal tubular cells: 176.8;Syncytiotrophoblasts: 489.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039780 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA039780: AB_10805594" "unprognostic (1.13e-1)" "unprognostic (4.03e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-1)" "unprognostic (3.31e-1)" "unprognostic (1.34e-2)" "unprognostic (2.65e-3)" "unprognostic (1.49e-1)" "unprognostic (8.96e-2)" "unprognostic (5.79e-3)" "unprognostic (6.30e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-3)" "unprognostic (4.91e-2)" "unprognostic (4.08e-2)" "unprognostic (1.58e-1)" "unprognostic (3.41e-2)" 49.2 73.5 44.0 56.4 47.2 100.0 47.8 49.8 58.9 44.0 44.8 49.1 51.2 39.2 62.7 41.0 49.1 38.9 51.9 46.0 52.2 75.4 72.4 51.0 80.5 46.9 46.9 36.0 45.4 84.2 45.6 60.6 49.9 49.5 56.6 69.7 45.5 48.8 44.9 28.3 50.3 54.1 50.5 46.4 45.1 39.7 47.7 58.3 67.2 54.0 73.2 63.4 32.0 53.9 232.1 94.9 57.1 51.8 86.7 84.0 111.3 174.3 127.3 120.7 79.6 145.9 129.1 125.6 192.2 128.7 107.5 76.1 89.6 110.3 177.7 124.8 77.3 130.9 48.4 68.1 94.6 77.1 102.5 74.1 86.5 107.6 92.1 86.7 132.2 58.2 31.0 359.9 173.4 137.6 107.5 46.1 65.4 134.2 99.0 79.0 73.8 215.4 102.6 132.7 64.2 39.8 106.4 64.4 74.8 71.2 133.6 96.2 125.7 65.1 41.1 121.1 172.6 261.3 151.4 176.1 88.8 142.1 56.9 218.1 163.8 142.5 133.7 138.4 148.5 119.6 111.3 125.4 126.5 102.3 87.4 110.1 198.8 106.3 155.7 90.7 132.3 324.7 44.0 47.2 49.8 58.9 46.0 52.2 46.9 46.9 49.9 50.5 47.7 53.9 80.6 60.9 67.9 0.0 53.4 0.0 0.0 0.0 0.0 0.0 97.2 66.5 0.0 0.0 29.1 108.5 0.0 215.1 114.7 0.0 97.8 166.8 0.0 63.9 46.8 35.5 0.0 0.0 0.0 135.0 230.6 30.9 0.0 64.7 45.4 31.5 0.0 0.0 238.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 72.5 0.0 0.0 123.5 0.0 0.0 0.0 0.0 206.0 0.0 0.0 21.0 0.0 0.0 176.8 32.8 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 489.3 48.1 63.4 0.0 0.0 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA4A "CORD10, FLJ12287, SEMAB, SemB" ENSG00000196189 "Semaphorin 4A" Q9H3S1 1 156147366-156177752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Angiogenesis, Differentiation, Immunity, Neurogenesis" "Developmental protein" "Cone-rod dystrophy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 51.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 63.7;Plasma cells: 61.2;Skeletal myocytes: 100.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 123.9;eosinophil: 120.2;intermediate monocyte: 132.7;myeloid DC: 183.0;neutrophil: 210.7;non-classical monocyte: 76.1" "Group enriched" "Detected in all" 13 "dendritic cells: 183.0;granulocytes: 210.7;monocytes: 132.7" "Cell line enhanced" "Detected in many" "Karpas-707: 151.8;U-698: 67.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069136 Supported NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA069136: AB_2686093" "unprognostic (1.90e-1)" "unprognostic (2.39e-2)" "unprognostic (4.24e-1)" "unprognostic (5.20e-2)" "unprognostic (8.04e-2)" "prognostic favorable (1.09e-4)" "unprognostic (1.97e-1)" "unprognostic (2.50e-2)" "unprognostic (3.51e-1)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (8.20e-4)" "unprognostic (8.77e-2)" "unprognostic (4.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.28e-2)" 6.1 1.0 22.7 24.8 21.5 37.5 9.1 6.1 23.2 10.8 4.7 6.9 3.6 3.0 51.3 32.5 7.9 8.8 3.0 25.3 23.0 18.1 2.1 15.2 31.5 12.2 15.5 5.2 4.0 1.5 3.6 1.8 15.3 16.3 6.1 2.0 19.2 12.5 3.1 32.3 4.8 3.6 11.4 26.9 10.6 4.1 29.0 8.1 23.1 2.2 33.1 10.8 17.4 13.1 12.6 0.0 0.5 0.0 0.0 0.9 0.3 0.2 0.4 0.1 0.2 0.1 0.3 8.1 0.3 0.6 0.1 11.7 0.9 10.0 0.4 3.5 0.0 0.4 0.2 0.4 0.4 18.5 1.1 0.6 9.2 0.2 0.4 2.3 0.9 2.8 1.3 151.8 0.5 15.2 0.1 6.5 3.6 12.4 0.0 0.6 0.3 5.4 17.9 24.1 0.1 0.3 0.0 19.2 1.0 1.7 22.3 23.3 0.9 0.0 0.1 0.0 0.0 29.3 3.0 67.6 0.5 17.5 0.4 16.0 123.9 120.2 4.0 132.7 8.5 13.2 1.3 8.0 183.0 10.9 0.2 1.3 210.7 4.3 76.1 25.7 1.4 66.4 22.7 21.5 6.1 23.2 25.3 23.0 12.2 15.5 15.3 11.4 29.0 13.1 13.6 19.2 63.7 25.8 13.9 23.5 22.5 25.8 24.5 1.9 28.3 27.6 5.9 14.3 13.8 40.5 0.0 0.9 9.8 6.5 1.9 6.1 6.4 12.9 21.6 9.5 3.6 1.3 7.5 0.7 0.4 20.9 22.4 33.5 17.7 0.6 9.3 0.6 15.4 0.0 5.2 24.1 8.2 22.8 42.1 4.3 1.8 37.8 16.0 1.0 32.6 6.3 2.1 1.0 1.0 1.1 7.2 1.2 61.2 14.2 0.8 0.7 9.6 0.4 0.0 100.1 11.3 3.1 0.7 39.0 27.6 1.8 10.0 1.4 17.6 15.6 SEPHS1 "SPS, SPS1" ENSG00000086475 "Selenophosphate synthetase 1" P49903 10 13317428-13348298 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037645, HPA062118" Enhanced Uncertain Nucleoplasm NA NA 21000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "HPA037645: AB_10671631, HPA062118: AB_2732676" "unprognostic (8.18e-3)" "unprognostic (1.79e-1)" "unprognostic (1.06e-3)" "unprognostic (2.07e-1)" "unprognostic (3.50e-2)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.16e-7)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (2.61e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.09e-1)" "unprognostic (1.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (5.11e-2)" 27.8 28.6 23.2 23.6 23.9 25.3 33.5 25.3 22.3 25.6 28.1 31.2 23.2 32.3 35.9 24.6 35.3 23.8 30.8 21.7 24.1 56.5 48.6 24.3 29.3 26.7 28.4 35.7 33.6 48.1 23.5 27.8 23.1 26.4 32.7 25.0 26.9 24.7 33.3 20.9 24.6 33.2 25.9 21.8 25.6 22.1 24.6 64.3 55.4 36.6 34.3 24.8 17.4 24.4 127.7 90.8 182.4 176.3 59.4 45.1 85.8 55.4 42.6 115.6 97.9 103.5 116.4 123.1 67.2 65.0 55.9 79.6 195.2 91.4 120.5 186.7 80.9 67.4 66.8 132.9 61.4 92.0 41.4 39.6 64.6 67.7 39.5 53.9 95.0 255.9 90.7 97.5 83.2 168.1 228.8 39.3 301.8 119.8 40.9 176.3 88.8 73.7 62.2 51.0 64.5 119.5 169.6 74.1 75.7 157.7 93.8 96.1 64.1 51.1 96.3 67.6 117.6 71.3 143.4 228.1 41.2 67.6 41.9 10.2 11.6 8.8 7.7 17.1 9.5 9.5 7.8 8.9 13.6 6.4 10.0 9.4 1.7 15.4 24.8 15.4 13.3 8.3 23.2 23.9 25.3 22.3 21.7 24.1 26.7 28.4 23.1 25.9 24.6 24.4 24.1 12.8 13.1 8.1 12.3 17.2 16.5 19.3 9.6 17.1 23.8 19.4 14.1 20.0 18.0 22.0 0.0 31.6 27.1 17.6 33.2 26.4 13.5 16.9 15.4 26.1 16.7 19.3 8.2 30.1 45.2 18.0 11.7 16.1 15.8 27.7 19.6 32.7 21.1 21.9 8.3 13.7 20.3 10.1 11.7 14.1 14.9 13.1 16.0 4.7 8.0 35.2 9.2 4.0 12.9 34.1 15.3 18.4 18.7 17.5 16.4 44.6 13.4 15.6 6.6 14.2 26.1 17.6 21.2 15.0 16.9 25.6 13.2 25.9 18.0 15.1 SEPTIN1 "DIFF6, PNUTL3, SEPT1" ENSG00000180096 "Septin 1" Q8WYJ6 16 30378133-30395991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 16.7;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "B-cells: 6.7;Cytotrophoblasts: 11.4;dendritic cells: 25.9;Fibroblasts: 4.9;Hofbauer cells: 9.2;Plasma cells: 10.2;Syncytiotrophoblasts: 4.9;T-cells: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 38.2;JURKAT: 48.5;MOLT-4: 66.3;REH: 39.0;U-266/70: 21.6;U-266/84: 33.4;U-698: 23.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA041566, HPA060339, HPA073635" Enhanced Approved "Actin filaments" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA041566: AB_10794671, HPA060339: , HPA073635: " "unprognostic (3.65e-3)" "prognostic favorable (9.72e-5)" "unprognostic (5.06e-2)" "prognostic favorable (3.04e-5)" "unprognostic (3.32e-4)" "prognostic favorable (6.63e-4)" "unprognostic (2.08e-1)" "prognostic favorable (7.24e-5)" "unprognostic (1.24e-2)" "unprognostic (6.52e-3)" "prognostic favorable (2.22e-4)" "unprognostic (3.46e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (3.95e-1)" "unprognostic (1.72e-2)" 1.6 0.9 1.0 3.6 1.1 0.7 1.1 1.2 1.9 1.9 1.0 3.4 4.1 1.4 0.7 2.0 2.0 0.3 0.8 1.0 1.1 1.4 1.9 2.6 15.3 1.0 1.0 1.6 0.8 0.5 0.7 0.3 1.1 1.7 0.0 0.1 3.2 0.8 0.2 1.3 16.7 0.7 1.0 35.9 4.4 0.2 1.4 16.0 1.9 0.6 6.6 2.0 1.6 1.0 0.3 0.0 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 38.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 7.3 3.0 0.0 0.0 0.3 0.0 5.1 1.2 0.2 0.1 0.1 0.0 0.7 0.0 48.5 0.3 16.7 0.0 0.0 66.3 1.4 0.0 0.0 0.7 39.0 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 21.6 33.4 23.2 0.6 7.0 0.0 118.4 2.5 102.2 319.3 2.3 245.1 170.1 286.7 292.4 9.6 179.4 264.6 268.7 8.5 230.4 1.6 270.6 329.6 272.6 1.0 1.1 1.2 1.9 1.0 1.1 1.0 1.0 1.1 1.0 1.4 1.0 1.2 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 11.4 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 4.9 6.1 0.0 0.0 0.0 SETD3 "C14orf154, FLJ23027" ENSG00000183576 "SET domain containing 3, actin histidine methyltransferase" Q86TU7 14 99397748-99480889 "Enzymes, Predicted intracellular proteins" "Actin-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 206.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003591, HPA003639" Approved Approved Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA003591: AB_1079930, HPA003639: AB_1079931" "unprognostic (6.82e-2)" "unprognostic (2.66e-2)" "unprognostic (8.07e-2)" "unprognostic (2.16e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.46e-4)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (2.01e-1)" "unprognostic (4.42e-1)" "prognostic favorable (1.89e-15)" "unprognostic (6.81e-2)" "unprognostic (3.21e-1)" "unprognostic (2.20e-1)" "unprognostic (2.62e-3)" 38.8 26.6 49.6 25.2 50.6 23.5 30.1 46.9 59.2 29.2 45.1 49.5 36.3 26.2 83.5 36.6 46.6 29.4 79.0 48.1 47.8 96.1 47.2 37.4 24.1 46.4 45.5 22.0 37.6 40.1 21.6 42.6 45.9 35.9 37.9 64.5 57.8 41.6 174.0 31.6 37.4 39.4 46.2 28.4 29.1 85.0 52.2 24.5 53.4 118.2 24.8 36.3 24.4 52.1 39.9 44.6 33.1 31.7 37.6 42.0 117.1 49.4 37.4 50.3 51.1 43.5 65.7 38.8 39.5 55.6 39.5 50.4 40.8 55.2 79.6 38.5 22.0 35.3 27.8 40.2 46.9 53.6 51.2 29.6 71.3 44.7 64.8 37.9 63.4 57.2 28.3 56.9 56.3 74.7 56.6 57.9 19.9 98.5 50.7 34.1 67.8 32.0 72.6 48.4 58.9 27.4 44.3 45.4 38.4 59.7 61.6 46.2 56.6 22.6 31.5 153.8 38.2 40.6 49.3 42.1 42.6 52.5 35.3 7.6 18.1 24.9 17.7 21.5 20.6 11.4 15.0 16.6 22.4 8.9 12.3 15.4 10.8 20.6 19.2 14.1 12.2 14.8 49.6 50.6 46.9 59.2 48.1 47.8 46.4 45.5 45.9 46.2 52.2 52.1 31.1 25.6 44.5 43.1 16.9 24.3 18.6 14.4 21.6 26.0 22.8 17.1 83.0 18.6 24.8 25.8 27.1 61.9 37.3 37.2 33.2 24.7 206.6 29.9 24.9 29.1 21.7 11.3 47.7 28.0 45.4 22.2 17.3 30.7 32.9 7.5 22.9 27.5 35.8 18.5 43.6 28.2 14.2 29.7 23.2 121.0 19.0 35.9 10.6 52.5 27.9 47.6 60.8 38.2 36.8 25.7 20.3 21.1 23.6 26.1 30.1 101.5 28.1 39.5 6.6 25.3 23.0 130.4 73.0 25.0 32.4 30.0 27.9 9.2 30.5 20.8 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 SGPP2 "FLJ39004, SPP2" ENSG00000163082 "Sphingosine-1-phosphate phosphatase 2" Q8IWX5 2 222424543-222562621 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.0;Excitatory neurons: 43.5;Glandular and luminal cells: 54.2;Microglial cells: 48.7;Urothelial cells: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.2;EFO-21: 13.0;hTCEpi: 52.6;RPTEC TERT1: 59.0;SCLC-21H: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.56e-3)" "unprognostic (1.79e-1)" "unprognostic (8.50e-2)" "unprognostic (2.97e-2)" "unprognostic (1.24e-3)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.31e-2)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.74e-2)" "unprognostic (2.69e-2)" 2.8 6.1 11.1 4.0 12.8 1.4 5.3 15.0 15.3 13.3 2.1 17.3 17.3 2.7 3.8 21.4 13.2 11.5 5.2 11.0 13.7 16.4 0.4 8.0 3.9 17.9 10.9 0.5 3.1 26.8 5.9 0.1 17.6 1.5 18.1 3.6 7.9 7.6 0.8 22.4 18.2 1.4 9.7 1.0 25.1 1.6 15.2 5.3 21.2 0.0 15.2 22.3 10.0 9.8 1.4 1.1 0.4 1.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 16.2 0.6 13.0 0.0 0.2 0.3 0.2 0.1 0.0 0.3 4.6 1.0 0.4 0.0 0.0 1.7 0.8 0.0 52.6 0.0 0.2 0.0 0.0 0.7 0.3 0.6 0.0 0.8 0.4 1.2 0.5 10.6 0.4 0.7 0.4 0.6 59.0 3.7 16.5 0.6 0.0 1.9 0.1 0.8 0.2 0.1 0.0 0.2 0.5 0.6 0.5 0.5 0.4 1.0 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 11.1 12.8 15.0 15.3 11.0 13.7 17.9 10.9 17.6 9.7 15.2 9.8 0.1 3.2 11.5 1.3 2.2 3.7 4.4 29.1 4.6 5.3 1.6 1.5 6.9 7.2 26.2 12.9 6.2 0.1 0.6 20.2 1.9 14.5 9.7 33.0 4.8 1.5 1.2 0.0 43.5 1.8 0.3 1.4 25.5 54.2 0.0 0.4 0.0 0.1 0.2 1.7 15.8 5.5 14.2 0.0 1.1 3.7 0.6 0.8 0.0 48.7 0.1 0.7 1.0 2.5 1.1 9.3 16.3 0.4 2.3 7.5 13.1 0.5 20.4 5.9 0.0 2.1 1.7 3.1 1.0 26.3 14.3 2.5 2.5 0.3 9.9 39.4 SHMT1 "CSHMT, MGC15229, MGC24556, SHMT" ENSG00000176974 "Serine hydroxymethyltransferase 1" P34896 17 18327860-18363563 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 168.5;liver: 398.7" "Group enriched" "Detected in many" 4 "Hepatocytes: 307.7;Proximal tubular cells: 435.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023314, HPA078682" Enhanced Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA023314: AB_1856830, HPA078682: " "unprognostic (4.76e-2)" "unprognostic (1.98e-2)" "unprognostic (5.46e-2)" "unprognostic (3.76e-1)" "unprognostic (2.45e-1)" "unprognostic (8.44e-3)" "prognostic favorable (2.52e-4)" "unprognostic (7.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.42e-1)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "prognostic favorable (8.54e-6)" "unprognostic (1.70e-2)" "unprognostic (2.66e-1)" "unprognostic (2.57e-3)" "unprognostic (4.04e-2)" 37.5 9.4 8.1 4.0 9.4 9.5 36.3 12.6 9.5 13.6 7.1 17.5 13.8 7.6 4.9 59.2 13.1 7.7 5.7 8.8 8.5 168.5 398.7 10.3 9.0 10.8 9.3 11.7 8.8 85.7 4.1 7.7 10.7 10.1 6.1 3.1 30.0 10.0 18.8 22.6 24.4 3.7 8.0 21.7 13.3 12.8 9.4 21.1 23.5 18.6 17.6 11.5 19.3 16.0 39.6 28.9 5.5 34.5 29.9 15.8 63.0 11.3 10.3 30.8 31.2 22.1 22.5 26.8 27.8 3.6 16.4 18.8 32.4 39.7 24.3 17.3 30.6 13.0 39.9 21.6 7.2 4.4 11.0 21.1 13.6 23.1 7.2 10.9 9.7 32.3 10.0 10.9 11.3 12.4 46.0 13.9 17.4 43.6 5.1 29.7 48.5 34.7 69.3 17.0 24.0 5.3 82.7 14.9 21.4 50.2 64.5 19.4 2.6 5.7 14.0 71.4 17.6 10.7 20.5 7.1 10.3 12.7 16.5 10.2 4.7 5.2 5.3 5.9 8.1 4.4 6.6 5.5 3.5 3.7 6.8 6.4 0.2 8.5 5.2 1.1 11.2 4.3 8.1 9.4 12.6 9.5 8.8 8.5 10.8 9.3 10.7 8.0 9.4 16.0 11.2 12.8 31.0 3.3 10.4 10.3 21.7 16.5 18.8 3.1 22.7 13.8 2.7 42.9 11.2 36.8 4.2 23.7 5.2 8.9 82.2 13.7 10.9 6.2 1.9 7.4 1.2 28.0 5.2 7.7 76.1 8.0 9.2 10.1 8.2 9.9 13.6 307.7 39.6 0.0 4.8 12.9 4.1 36.8 3.5 5.5 5.9 17.2 12.4 9.4 4.4 33.8 5.2 2.0 11.4 5.3 9.7 3.0 20.3 5.9 53.7 435.7 3.5 4.2 19.7 8.1 4.4 30.0 21.4 35.4 10.5 8.5 10.1 4.9 32.2 10.9 SIAE "CSE-C, LSE, MGC87009, YSG2" ENSG00000110013 "Sialic acid acetylesterase" Q9HAT2 11 124633113-124695707 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 104.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 58.0;Cardiomyocytes: 59.5;Distal enterocytes: 102.4;Paneth cells: 53.0;Proximal enterocytes: 51.6;Undifferentiated cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 88.6;ASC TERT1: 91.3;HSkMC: 98.9;OE19: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038052, HPA038053" Approved "Intracellular and membrane" NA NA 2200000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA038052: AB_10671518, HPA038053: AB_10673039" "unprognostic (9.97e-2)" "unprognostic (1.28e-2)" "unprognostic (2.48e-3)" "prognostic favorable (4.66e-5)" "unprognostic (3.30e-2)" "unprognostic (5.20e-2)" "unprognostic (4.90e-2)" "unprognostic (4.32e-2)" "unprognostic (1.18e-1)" "unprognostic (2.26e-1)" "unprognostic (2.45e-1)" "unprognostic (9.19e-2)" "prognostic favorable (4.42e-11)" "unprognostic (7.24e-2)" "unprognostic (3.22e-1)" "unprognostic (4.49e-2)" "unprognostic (1.92e-2)" 18.7 17.3 16.8 11.8 21.6 3.7 15.9 26.9 19.8 13.0 38.9 97.8 34.3 7.1 34.3 13.6 19.3 16.7 43.8 16.1 27.1 62.1 43.4 20.6 5.8 25.3 23.7 5.7 17.3 45.3 14.4 11.8 24.7 20.4 104.4 6.2 18.4 15.3 26.7 13.0 35.8 10.4 23.0 9.1 19.0 10.3 24.9 3.7 54.0 33.3 6.7 16.8 7.8 26.3 8.9 14.0 8.0 34.6 88.6 91.3 20.9 16.8 24.0 4.3 2.6 10.9 61.4 5.5 24.2 21.5 9.4 17.3 12.8 18.7 4.2 26.0 3.9 8.6 3.7 11.1 41.8 0.7 7.2 98.9 24.9 11.4 17.3 58.5 30.6 11.0 7.1 37.5 14.8 16.5 0.2 0.6 5.0 97.7 28.5 3.2 0.2 8.4 51.4 12.1 2.4 5.1 46.5 18.6 8.0 24.0 36.8 3.2 34.1 23.6 4.3 26.5 4.0 9.4 7.5 0.7 8.3 4.6 9.8 7.6 2.9 0.1 0.4 2.1 0.3 0.5 1.3 0.6 1.9 0.7 1.7 1.1 0.5 0.2 3.7 0.5 0.6 1.8 16.8 21.6 26.9 19.8 16.1 27.1 25.3 23.7 24.7 23.0 24.9 26.3 4.2 19.2 58.0 11.8 2.4 3.2 6.3 6.7 7.4 6.5 10.1 4.3 59.5 12.8 9.4 36.8 0.0 7.6 0.6 102.4 9.8 15.2 14.0 9.1 9.3 6.9 14.5 5.2 15.0 3.8 8.8 7.5 12.8 14.0 1.3 3.9 8.9 30.0 4.5 5.0 9.1 31.0 4.1 3.5 1.6 12.0 3.1 4.3 3.6 6.5 4.5 1.9 1.0 8.0 6.7 5.2 53.0 1.2 3.9 7.4 51.6 26.2 11.9 1.8 0.0 4.9 7.9 14.8 9.6 12.2 5.3 6.7 2.0 8.9 63.6 7.1 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIGLEC9 CD329 ENSG00000129450 "Sialic acid binding Ig like lectin 9" Q9Y336 19 51124906-51136651 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.7" "Cell type enhanced" "Detected in some" "Hofbauer cells: 42.1;Kupffer cells: 39.8;Langerhans cells: 13.4;Macrophages: 26.8;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 198.9;intermediate monocyte: 182.5;myeloid DC: 169.1;neutrophil: 212.0;non-classical monocyte: 121.9" "Group enriched" "Detected in many" 13 "dendritic cells: 169.1;granulocytes: 212.0;monocytes: 198.9" "Group enriched" "Detected in some" 10 "Karpas-707: 23.4;RPMI-8226: 16.5" HPA010682 Uncertain NA NA 270000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" "HPA010682: AB_1079968" "unprognostic (2.31e-1)" "unprognostic (3.99e-2)" "unprognostic (1.03e-2)" "unprognostic (1.36e-1)" "unprognostic (4.69e-2)" "unprognostic (6.86e-2)" "unprognostic (5.10e-2)" "unprognostic (2.10e-1)" "unprognostic (1.31e-1)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (7.03e-3)" "prognostic unfavorable (6.17e-5)" "unprognostic (6.56e-2)" "unprognostic (7.38e-3)" "unprognostic (2.95e-1)" "unprognostic (1.73e-1)" 8.0 5.4 2.0 17.9 2.1 9.0 1.9 2.2 4.3 1.4 2.8 2.1 1.7 0.9 0.2 0.9 2.5 5.0 2.1 1.9 3.4 1.4 5.5 8.3 5.0 5.4 4.0 3.2 1.2 4.1 0.9 7.9 5.0 1.1 2.4 0.3 1.5 0.9 0.4 0.5 2.2 6.4 4.0 20.7 1.4 1.7 6.2 1.4 0.9 1.3 2.5 5.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 23.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.0 1.5 0.0 17.3 198.9 1.6 15.2 182.5 8.6 0.2 2.5 5.8 169.1 0.1 0.6 2.7 212.0 3.1 121.9 9.2 0.9 84.9 2.0 2.1 2.2 4.3 1.9 3.4 5.4 4.0 5.0 4.0 6.2 5.9 0.1 0.0 0.5 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.7 0.0 1.3 0.0 0.0 0.2 2.7 0.0 0.0 0.0 1.8 0.0 0.1 1.1 0.0 0.0 0.2 0.0 0.4 0.5 0.0 0.0 0.0 0.1 5.3 0.8 42.1 0.0 0.2 0.0 0.0 39.8 13.4 0.4 5.0 26.8 0.0 5.6 10.4 0.0 7.2 0.0 0.1 0.0 0.0 2.2 0.4 0.0 0.0 0.1 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.1 0.3 1.3 2.8 0.0 0.0 SIL1 "BAP, MSS, ULG5" ENSG00000120725 "SIL1 nucleotide exchange factor" Q9H173 5 138946724-139293557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011949 Enhanced "Intracellular and membrane" NA NA 710000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA011949: AB_1856875" "unprognostic (1.06e-1)" "unprognostic (9.01e-2)" "unprognostic (2.04e-1)" "prognostic favorable (4.34e-4)" "prognostic unfavorable (4.27e-4)" "unprognostic (9.12e-3)" "unprognostic (3.60e-1)" "unprognostic (2.45e-1)" "unprognostic (1.33e-1)" "unprognostic (6.91e-2)" "unprognostic (2.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.21e-3)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (6.79e-2)" "unprognostic (1.22e-2)" 26.4 46.4 9.0 19.7 10.6 24.1 21.6 8.5 11.8 21.7 17.9 20.0 24.6 21.7 32.5 16.5 19.2 23.2 29.5 9.2 9.3 20.9 54.9 22.6 14.1 10.6 9.9 19.1 67.7 33.7 28.5 28.7 10.5 23.9 12.8 5.7 36.7 25.8 41.4 23.2 16.4 17.2 8.2 17.3 29.5 49.8 11.3 9.0 36.2 18.0 10.0 20.6 16.2 10.3 33.7 34.9 11.3 56.2 84.0 48.3 65.0 54.0 58.2 26.6 57.3 36.9 78.9 12.4 89.7 74.2 32.2 29.8 12.0 76.0 15.8 33.7 20.7 16.4 23.9 40.9 67.2 4.9 72.6 60.7 73.1 46.4 79.0 42.7 40.5 15.4 8.7 131.3 32.2 52.1 12.4 15.1 2.4 38.6 4.2 8.9 7.8 92.7 38.9 17.7 19.5 13.0 46.3 44.3 74.5 24.8 38.4 30.6 30.6 46.8 10.9 17.9 23.6 56.3 31.6 8.2 34.3 38.1 39.9 18.1 47.7 19.4 17.4 52.4 10.9 20.1 12.1 16.8 51.3 14.7 12.1 15.1 5.7 22.1 42.3 37.3 11.7 27.1 9.0 10.6 8.5 11.8 9.2 9.3 10.6 9.9 10.5 8.2 11.3 10.3 22.5 19.2 47.0 51.6 32.5 22.0 33.4 61.6 15.4 9.0 33.8 21.6 30.3 38.6 48.1 42.3 37.5 121.2 19.0 41.5 11.7 61.8 109.1 25.5 37.0 21.9 33.5 7.6 75.7 81.7 104.2 46.3 38.7 32.1 60.3 29.2 29.3 143.8 70.3 25.2 73.7 64.3 52.9 33.9 21.0 195.7 28.6 36.7 48.0 49.6 113.8 15.2 17.5 66.4 57.6 46.2 34.9 22.2 114.5 32.1 51.1 46.5 51.6 26.6 19.7 21.4 27.7 96.9 61.8 13.0 23.9 153.6 16.9 60.3 43.0 30.1 SIRPB2 "dJ776F14.2, PTPN1L, PTPNS1L3" ENSG00000196209 "Signal regulatory protein beta 2" Q5JXA9 20 1470741-1491587 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.1" "Cell type enhanced" "Detected in some" "Hofbauer cells: 5.1;Kupffer cells: 20.0;Macrophages: 9.5;Microglial cells: 14.0;monocytes: 8.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "classical monocyte: 51.1;eosinophil: 31.7;intermediate monocyte: 30.4;myeloid DC: 21.1;neutrophil: 69.5;non-classical monocyte: 24.4" "Group enriched" "Detected in many" 329 "dendritic cells: 21.1;granulocytes: 69.5;monocytes: 51.1" "Cell line enhanced" "Detected in some" "A-431: 4.7;HBEC3-KT: 4.0;HMC-1: 7.8;hTCEpi: 8.5;HUVEC TERT2: 4.3;THP-1: 7.7;TIME: 3.7;U-937: 8.3" "Low region specificity" "Detected in all" "HPA011548, HPA048032" Uncertain Approved "Nuclear bodies" NA NA 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nuclear bodies" "HPA011548: AB_2668514, HPA048032: AB_2680236" "unprognostic (3.22e-2)" "unprognostic (5.57e-2)" "unprognostic (2.29e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (2.21e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.75e-1)" "unprognostic (2.38e-1)" "unprognostic (2.43e-1)" "unprognostic (3.50e-5)" "unprognostic (3.59e-3)" "unprognostic (9.24e-3)" "unprognostic (1.37e-1)" "unprognostic (1.06e-1)" 5.6 2.4 1.1 12.0 1.2 6.5 1.6 1.3 1.6 1.8 1.8 1.5 0.9 0.9 0.1 1.8 1.6 3.7 1.4 1.1 1.5 1.1 1.8 7.2 7.0 2.7 2.1 0.5 0.7 0.6 0.6 7.5 2.4 0.9 1.7 0.2 1.3 0.6 0.5 0.9 2.0 4.1 1.6 13.1 1.2 0.5 2.7 1.4 0.7 1.8 3.2 3.9 0.9 2.6 4.7 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 1.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 7.8 0.0 8.5 0.0 0.2 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 7.7 3.7 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 8.3 0.0 3.0 51.1 31.7 0.1 30.4 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.0 69.5 0.0 24.4 0.6 0.0 18.9 1.1 1.2 1.3 1.6 1.1 1.5 2.7 2.1 2.4 1.6 2.7 2.6 0.0 0.0 1.1 0.0 0.5 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.6 0.6 0.0 0.1 1.3 0.0 1.4 0.2 5.1 0.0 0.1 0.0 0.0 20.0 3.3 0.0 0.0 9.5 0.0 14.0 8.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.1 0.7 0.3 0.1 0.0 0.6 SKA2 "FAM33A, FLJ12758" ENSG00000182628 "Spindle and kinetochore associated complex subunit 2" Q8WVK7 17 59109857-59155260 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059235 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "HPA059235: AB_2683953" "unprognostic (2.67e-1)" "unprognostic (6.42e-3)" "unprognostic (9.69e-3)" "unprognostic (5.93e-3)" "unprognostic (2.07e-1)" "unprognostic (4.44e-2)" "unprognostic (7.70e-3)" "unprognostic (9.81e-2)" "unprognostic (2.74e-2)" "unprognostic (1.05e-2)" "unprognostic (3.96e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.59e-1)" "unprognostic (1.39e-1)" "unprognostic (4.75e-3)" "unprognostic (1.05e-1)" 19.9 12.6 30.8 20.1 33.4 24.2 11.8 43.3 39.5 18.4 29.1 22.1 18.8 20.3 12.5 24.4 18.1 13.0 34.5 27.8 36.3 21.9 22.4 16.1 33.6 34.3 37.6 16.7 11.5 26.1 14.9 22.9 34.3 16.3 20.0 44.4 10.9 19.9 12.6 13.9 16.8 24.6 37.2 15.8 18.3 12.5 34.4 53.7 25.5 20.4 28.5 20.3 18.1 38.3 217.6 78.6 249.4 85.6 32.4 24.5 76.8 107.1 102.8 163.1 182.5 120.2 122.6 114.1 118.8 87.0 124.3 90.9 162.9 149.3 231.0 197.8 127.4 179.4 142.2 75.1 36.8 142.3 112.5 35.6 63.1 104.8 84.5 64.4 77.2 127.3 114.3 164.5 117.1 297.7 215.4 71.9 66.6 238.3 145.1 114.0 281.3 81.0 121.4 93.2 112.3 96.2 119.1 53.8 66.9 165.4 179.2 112.0 68.0 160.5 153.4 130.5 244.8 111.7 255.6 135.9 85.4 105.3 117.6 26.7 13.1 17.2 18.7 23.5 14.4 18.4 25.6 24.1 15.4 13.7 19.8 22.4 2.4 22.9 38.3 18.3 48.3 12.8 30.8 33.4 43.3 39.5 27.8 36.3 34.3 37.6 34.3 37.2 34.4 38.3 24.8 25.6 18.2 23.2 24.6 21.4 21.6 49.2 25.6 36.1 10.8 17.1 46.3 12.8 26.7 9.2 25.0 62.6 25.8 16.1 39.2 38.3 20.8 22.4 30.2 26.9 10.3 96.8 10.9 25.2 61.7 26.9 30.5 21.0 18.3 26.6 25.4 33.0 46.3 50.5 20.1 23.0 14.2 37.0 22.6 9.4 27.1 28.2 23.2 15.0 42.9 49.3 39.1 15.1 26.3 31.9 24.7 25.6 52.0 8.9 12.8 32.1 26.8 39.4 0.0 13.8 41.5 38.8 30.7 34.1 13.5 30.9 35.0 33.8 35.2 18.9 SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 12.1;testis: 6.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Extravillous trophoblasts: 21.0;Spermatocytes: 21.7;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039272, HPA039356, HPA061534" Approved Supported "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle" "Centrosome, Cytosol" "HPA039272: AB_10805359, HPA039356: AB_10805475, HPA061534: " "unprognostic (3.46e-2)" "unprognostic (7.21e-2)" "unprognostic (2.15e-1)" "unprognostic (1.62e-2)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (9.73e-6)" "unprognostic (2.03e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.39e-2)" "unprognostic (0.00e+0)" "unprognostic (2.24e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" 0.2 0.1 0.2 2.5 0.2 4.7 0.8 0.1 0.3 0.2 0.0 1.7 1.0 0.5 0.0 1.9 0.2 0.4 0.0 0.5 0.2 0.1 0.2 0.2 4.3 0.2 0.2 0.0 0.0 0.0 0.0 1.6 0.2 0.0 3.0 0.0 0.2 0.0 0.0 1.8 2.1 1.1 0.2 0.7 1.0 6.3 0.3 12.1 0.1 0.1 3.7 0.4 0.5 0.2 26.1 13.0 25.8 20.5 0.9 5.1 19.1 35.0 14.8 42.1 28.7 23.4 27.8 35.6 10.0 19.3 18.5 24.4 34.4 15.2 54.7 30.3 15.9 47.3 7.7 12.7 0.0 39.5 17.7 1.5 1.0 34.9 15.4 4.2 20.7 30.6 26.3 14.2 33.9 21.0 60.7 37.8 27.9 42.8 23.8 36.5 50.3 15.8 12.2 9.9 30.1 11.1 11.8 17.1 8.1 17.9 15.3 33.5 8.7 16.0 23.8 17.0 43.9 9.0 19.7 34.5 4.4 31.1 51.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.2 0.2 0.1 0.3 0.5 0.2 0.2 0.2 0.2 0.2 0.3 0.2 0.4 0.0 0.0 0.0 2.6 2.0 0.7 2.4 0.0 0.1 0.9 0.8 0.8 0.0 1.8 0.0 0.0 8.7 1.0 2.1 0.0 1.2 6.3 2.8 0.9 1.4 0.0 12.8 0.8 1.3 21.0 2.1 1.5 1.6 0.0 5.8 1.8 0.4 5.5 0.0 0.6 1.8 2.0 1.9 2.9 7.7 1.5 1.6 0.0 1.9 0.8 0.3 3.1 0.0 0.2 1.0 1.6 1.2 8.5 0.3 0.4 0.6 2.0 0.4 0.0 0.3 2.3 21.7 18.2 5.8 2.8 2.2 1.2 0.5 5.0 0.7 SKP1 "EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L" ENSG00000113558 "S-phase kinase associated protein 1" P63208 5 134148935-134176964 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012982, HPA053745, HPA058134" Approved Supported Nucleoplasm,Cytosol No No 880000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "CAB012982: AB_2533076, HPA053745: AB_2682245, HPA058134: AB_2683617" "prognostic unfavorable (7.53e-4)" "unprognostic (1.97e-1)" "unprognostic (9.81e-3)" "unprognostic (1.07e-1)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (4.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.72e-1)" "unprognostic (2.73e-1)" "unprognostic (3.07e-1)" "prognostic favorable (5.20e-4)" "unprognostic (1.02e-2)" "unprognostic (2.06e-1)" "unprognostic (8.26e-2)" "unprognostic (2.40e-1)" 430.5 566.7 442.5 194.9 463.6 363.7 559.0 471.7 648.6 455.4 486.2 529.3 230.1 441.3 490.7 401.9 437.8 330.1 650.5 470.8 492.5 588.6 442.8 346.6 305.9 465.9 457.1 525.4 266.6 776.2 501.0 394.6 474.2 420.9 350.2 484.3 366.9 550.9 1056.8 419.5 354.9 422.6 494.4 304.8 385.9 380.4 470.5 456.1 551.5 814.1 332.0 452.9 391.6 515.0 657.0 500.1 730.3 986.5 1103.6 891.8 519.2 744.6 939.1 854.0 877.1 773.0 620.0 481.9 1084.9 1009.8 974.9 356.6 738.2 1124.1 988.3 442.6 519.5 380.7 724.0 555.8 518.7 296.3 452.0 771.1 886.2 750.1 588.7 1060.4 928.4 611.2 467.4 411.8 1295.2 515.6 642.0 314.8 423.9 619.6 530.7 349.2 780.7 591.7 952.3 724.6 594.6 463.8 1010.2 254.4 726.9 942.4 738.5 454.6 705.3 547.5 338.4 578.2 766.4 254.7 459.1 717.8 762.3 555.5 608.0 1745.5 851.4 1484.9 884.6 841.7 1011.4 1202.8 1264.6 1099.9 817.8 1094.4 1495.5 1174.8 811.4 1096.1 1027.0 728.1 1416.7 2538.6 442.5 463.6 471.7 648.6 470.8 492.5 465.9 457.1 474.2 494.4 470.5 515.0 430.1 285.2 306.3 64.0 403.6 674.3 1025.7 1354.7 380.1 230.0 539.8 558.4 700.9 497.6 767.4 594.1 73.0 881.0 417.7 441.8 1696.3 644.9 593.3 511.9 405.3 410.1 356.0 617.8 66.5 376.9 749.4 561.5 270.1 439.0 336.9 433.9 340.2 376.9 471.6 223.8 65.8 402.2 1192.2 296.1 505.1 1048.6 601.4 344.8 718.6 33.7 565.4 792.8 338.8 43.7 87.0 378.1 564.0 712.8 278.2 744.7 630.0 1577.8 965.7 217.5 506.2 480.4 668.1 753.5 652.7 349.0 645.6 1347.0 511.1 500.4 410.4 837.6 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLC12A8 CCC9 ENSG00000221955 "Solute carrier family 12 member 8" A0AV02 3 125082636-125212864 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 22.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 23.9;Excitatory neurons: 38.4;granulocytes: 17.8;Inhibitory neurons: 27.8;Intestinal goblet cells: 36.6;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.6;HHSteC: 33.6;OE19: 27.6;U-2197: 67.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031123 Uncertain Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "HPA031123: AB_2301872" "unprognostic (4.74e-2)" "unprognostic (1.46e-3)" "unprognostic (1.39e-1)" "unprognostic (5.91e-3)" "unprognostic (7.35e-3)" "unprognostic (1.79e-1)" "unprognostic (2.07e-1)" "unprognostic (3.76e-2)" "unprognostic (1.01e-1)" "unprognostic (7.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.13e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (7.18e-2)" "unprognostic (3.47e-2)" "unprognostic (2.57e-2)" "unprognostic (1.78e-2)" 1.5 1.1 2.9 1.2 3.2 0.0 2.3 1.0 3.1 1.4 11.7 3.5 5.6 0.6 3.6 4.1 2.0 8.3 0.6 3.4 2.4 3.2 6.8 2.2 0.6 1.6 2.0 0.3 10.0 4.3 2.2 2.7 1.9 2.8 4.2 0.1 11.9 0.6 0.1 1.3 3.6 0.7 1.0 0.3 4.1 2.3 2.0 0.5 22.9 0.0 0.9 2.1 2.2 2.0 14.7 0.0 2.7 0.0 3.3 4.6 6.7 0.8 2.0 0.9 1.7 19.6 6.8 0.0 1.9 5.6 2.8 8.5 0.0 0.0 0.5 0.0 0.0 0.0 7.2 0.0 33.6 0.0 1.0 8.7 8.3 1.9 0.9 16.3 0.0 0.0 0.0 0.6 1.3 3.9 0.0 0.0 9.3 27.6 0.7 0.0 0.2 0.0 6.8 1.3 4.2 0.0 7.0 8.4 0.1 0.9 15.6 0.4 0.2 0.2 1.3 67.9 0.0 0.1 1.9 5.0 3.3 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.2 1.0 3.1 3.4 2.4 1.6 2.0 1.9 1.0 2.0 2.0 0.2 0.0 0.5 7.2 0.1 1.0 1.3 3.3 3.4 0.0 5.6 4.3 1.1 2.8 2.5 23.9 0.0 0.5 0.1 1.6 0.0 3.9 0.3 0.8 1.4 0.3 5.4 0.0 38.4 3.5 6.5 2.1 7.7 2.7 17.8 1.8 0.0 9.4 0.9 0.0 27.8 36.6 0.0 0.0 0.7 0.5 0.0 0.5 0.0 7.5 2.1 0.0 1.0 31.7 2.0 2.9 3.4 0.0 0.2 6.2 2.6 1.5 0.4 0.0 0.0 0.2 0.7 0.6 0.4 4.3 0.3 3.0 0.8 0.1 5.6 1.0 SLC16A12 MCT12 ENSG00000152779 "Solute carrier family 16 member 12" Q6ZSM3 10 89430299-89556641 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" Cataract "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 92.2;epididymis: 51.8;kidney: 85.2;pancreas: 25.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 18.1;Leydig cells: 27.1;Peritubular cells: 26.7;Proximal tubular cells: 69.2" "Cancer enriched" "Detected in many" 10 "renal cancer: 18.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC TERT1: 23.0;HSkMC: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037587 Approved Mitochondria NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA037587: AB_2732475" "unprognostic (5.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.79e-2)" "unprognostic (2.28e-2)" "unprognostic (3.51e-1)" "unprognostic (5.35e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-2)" "unprognostic (2.42e-1)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic favorable (4.50e-12)" "unprognostic (3.84e-2)" "unprognostic (7.91e-2)" "unprognostic (8.29e-2)" "unprognostic (1.84e-3)" 1.8 2.5 0.8 0.1 1.1 0.0 1.9 1.0 2.7 9.2 92.2 0.8 0.1 1.4 51.8 0.3 4.1 0.1 4.9 2.9 0.3 85.2 2.0 2.5 0.1 0.5 1.6 1.3 25.3 0.1 3.4 11.6 0.6 0.6 0.2 0.0 0.4 14.1 1.6 0.5 0.3 0.3 1.2 0.0 1.0 3.3 1.0 0.4 6.2 2.5 0.0 0.4 0.7 0.6 0.2 0.0 0.0 0.0 3.0 23.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.5 0.0 3.7 0.0 0.0 8.2 0.2 1.2 1.5 2.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 1.0 2.7 2.9 0.3 0.5 1.6 0.6 1.2 1.0 0.6 0.8 3.2 3.9 3.3 0.6 0.0 2.2 0.1 0.0 0.1 4.6 0.1 3.3 1.5 2.9 14.7 0.0 16.4 0.1 0.0 15.6 0.0 8.3 11.5 0.8 1.3 18.1 0.0 0.3 4.1 1.1 2.2 0.0 1.0 1.3 0.0 0.4 2.2 1.2 3.3 0.4 0.2 0.0 0.0 0.9 4.8 27.1 1.0 0.0 11.2 0.1 0.0 0.0 0.0 0.4 2.1 0.1 26.7 0.0 0.7 0.0 69.2 6.2 0.6 13.1 3.4 7.8 0.2 0.5 0.0 0.3 9.0 0.9 0.1 0.0 1.8 SLC20A2 "Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1" ENSG00000168575 "Solute carrier family 20 member 2" Q08357 8 42416475-42541926 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Phosphate transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 130.6;skeletal muscle: 131.2" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 250.2;Oligodendrocytes: 151.7;Urothelial cells: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 132.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026540 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA026540: AB_1855408" "prognostic unfavorable (7.67e-4)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.27e-2)" "unprognostic (2.12e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.95e-1)" "unprognostic (7.62e-2)" "unprognostic (2.06e-1)" "unprognostic (3.43e-2)" "prognostic favorable (1.01e-4)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (5.86e-2)" "unprognostic (4.95e-2)" 11.9 8.0 33.4 9.8 45.3 3.0 12.1 55.4 37.1 15.8 130.6 22.8 46.7 18.5 9.9 32.7 24.5 15.1 63.2 30.1 48.7 17.5 39.7 15.1 6.5 46.5 56.5 8.1 51.6 15.0 10.5 13.5 47.5 13.6 19.0 7.5 87.9 17.6 131.2 23.3 18.8 17.9 42.7 7.4 15.1 15.9 67.8 11.9 82.8 57.6 9.1 22.0 21.7 52.8 52.7 14.3 19.0 16.0 10.4 8.8 41.1 46.9 80.8 23.9 58.7 38.9 132.9 17.4 53.6 42.1 13.5 81.1 11.4 45.2 41.6 4.3 8.7 27.8 4.8 22.0 14.9 9.9 12.3 9.5 40.2 24.7 22.7 16.7 12.0 13.7 27.2 14.0 47.3 14.4 18.1 16.1 19.2 50.5 8.8 14.9 20.9 18.5 21.4 47.5 5.1 19.2 12.8 21.8 12.8 15.0 17.5 17.3 34.9 50.0 17.4 12.3 25.7 9.0 22.2 12.6 15.8 19.5 28.3 3.2 2.2 0.2 3.6 1.6 4.3 2.1 4.0 3.5 3.7 2.1 4.8 3.7 0.8 6.8 1.3 2.0 4.1 3.1 33.4 45.3 55.4 37.1 30.1 48.7 46.5 56.5 47.5 42.7 67.8 52.8 11.1 28.9 18.6 51.6 9.1 98.9 250.2 22.7 96.2 13.4 21.7 14.9 60.2 14.3 21.7 16.5 16.7 23.9 14.3 76.2 13.7 29.6 10.4 79.9 15.8 18.9 12.0 6.9 88.9 31.4 23.7 15.8 15.8 61.2 3.8 17.1 6.4 30.7 10.2 6.7 88.4 11.5 18.3 7.7 12.2 10.0 7.2 10.2 10.6 78.7 7.3 14.4 14.4 63.3 151.7 47.4 35.8 11.7 8.6 76.6 20.0 7.3 57.6 10.2 6.6 22.9 28.3 5.2 7.2 73.9 74.3 25.4 14.2 23.7 12.5 170.3 SLC25A23 "APC2, FLJ30339, MGC2615" ENSG00000125648 "Solute carrier family 25 member 23" Q9BV35 19 6436079-6465203 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 238.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 164.2;Proximal enterocytes: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009675, HPA050883" Approved Supported Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA009675: AB_2668252, HPA050883: AB_2681260" "unprognostic (3.51e-1)" "unprognostic (1.53e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.05e-2)" "unprognostic (3.65e-3)" "unprognostic (3.43e-2)" "unprognostic (1.31e-3)" "unprognostic (1.27e-1)" "unprognostic (3.82e-1)" "unprognostic (1.30e-1)" "unprognostic (3.25e-1)" "prognostic favorable (1.10e-12)" "unprognostic (8.95e-2)" "unprognostic (3.20e-1)" "unprognostic (5.44e-2)" "unprognostic (4.22e-1)" 28.8 38.0 144.8 12.0 238.7 0.8 18.0 77.5 200.1 32.1 72.0 94.4 39.3 41.8 24.0 64.7 36.6 21.4 79.0 206.5 95.1 45.0 38.5 24.0 9.2 108.8 98.2 33.6 24.2 58.8 22.2 4.7 109.5 35.0 49.1 41.2 68.9 40.0 90.8 33.5 40.5 65.5 82.7 11.9 41.3 9.5 101.4 7.2 60.7 78.2 31.2 55.8 31.1 115.8 58.2 22.9 32.2 101.9 42.3 18.6 14.9 17.0 26.4 31.0 37.2 58.2 37.1 32.2 40.0 41.3 34.1 48.0 66.3 39.0 24.3 0.1 58.6 23.2 46.7 46.2 39.2 1.6 52.5 53.3 33.4 27.6 12.0 62.9 32.8 34.7 68.8 39.4 6.2 41.6 20.7 32.8 23.6 61.0 71.1 10.0 8.8 49.4 83.3 10.2 2.4 31.9 11.7 70.8 30.0 34.8 37.1 50.1 11.7 9.8 41.8 2.6 11.2 7.3 10.7 28.3 4.5 54.2 15.6 0.5 0.0 0.0 2.0 0.0 0.4 1.0 1.1 0.9 0.2 0.4 1.5 1.4 0.0 0.3 0.0 0.4 1.3 0.4 144.8 238.7 77.5 200.1 206.5 95.1 108.8 98.2 109.5 82.7 101.4 115.8 6.2 9.6 20.9 11.8 7.0 10.5 8.8 11.5 12.0 13.1 18.9 15.6 39.5 47.1 10.0 46.0 8.4 1.4 4.5 164.2 19.6 54.7 15.9 8.2 6.4 8.0 13.8 1.3 24.7 28.5 1.8 10.2 12.8 17.5 7.0 17.9 16.1 38.0 2.7 8.4 17.9 34.5 10.2 3.0 2.6 71.2 19.0 1.4 17.8 12.2 1.0 28.7 4.1 17.1 12.6 55.5 57.9 29.3 17.6 13.6 106.8 28.7 6.4 22.0 13.1 12.1 12.7 0.5 4.6 34.1 23.3 0.8 5.2 39.5 34.2 30.3 SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 330.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 31.6;Endometrial stromal cells: 23.9;Enteroendocrine cells: 45.2;Glandular and luminal cells: 52.0;Hepatic stellate cells: 24.7" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Endometrium - Transcription" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" 1.5 0.1 0.1 0.0 0.2 0.0 0.3 0.2 0.1 1.4 0.2 0.2 0.1 2.7 0.1 0.0 0.5 0.6 0.7 0.0 0.1 23.8 0.0 0.1 3.7 0.1 0.1 0.1 1.2 0.2 0.3 0.3 0.2 0.1 0.4 0.0 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 6.1 0.5 0.2 0.0 330.3 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.4 3.9 0.0 1.5 5.9 0.1 0.3 0.4 0.2 0.0 0.0 1.9 0.6 1.1 0.0 0.3 23.9 0.0 0.0 0.0 0.3 13.7 0.1 11.9 31.6 23.9 1.5 45.2 0.0 0.5 0.2 0.0 1.5 1.5 52.0 0.0 0.1 24.7 0.1 0.1 0.0 0.7 0.7 2.0 0.6 0.3 2.9 3.7 0.2 3.6 0.0 0.0 0.1 0.0 0.0 3.8 1.4 0.2 0.0 0.0 0.3 0.0 0.3 1.9 0.2 0.0 0.0 4.4 0.6 1.1 0.0 0.1 0.0 0.4 0.5 0.3 0.1 SLC30A5 "FLJ12496, FLJ12756, MGC5499, ZnT-5, ZNT5, ZNTL1, ZTL1" ENSG00000145740 "Solute carrier family 30 member 5" Q8TAD4 5 69093949-69131069 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035373 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Nucleoplasm "HPA035373: AB_10794630" "unprognostic (9.81e-3)" "unprognostic (3.33e-1)" "unprognostic (2.82e-2)" "unprognostic (8.16e-2)" "unprognostic (1.65e-1)" "unprognostic (3.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.47e-2)" "unprognostic (4.65e-2)" "unprognostic (5.41e-2)" "unprognostic (3.57e-2)" "unprognostic (2.92e-1)" "unprognostic (1.49e-1)" "unprognostic (2.53e-2)" "unprognostic (2.07e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" 25.8 25.6 9.8 21.0 10.3 19.6 30.3 11.7 15.9 29.7 17.4 26.9 24.7 25.6 38.2 19.3 24.3 24.0 24.1 9.7 10.6 29.1 29.0 21.1 24.7 10.1 11.4 22.3 33.0 35.9 24.0 27.4 10.2 29.4 24.7 18.5 30.8 24.0 16.4 27.1 23.6 22.8 9.7 21.9 26.3 16.4 10.9 20.8 37.5 16.5 23.7 23.6 19.7 12.1 37.4 29.9 26.3 46.2 69.1 53.2 82.5 58.8 53.6 36.4 55.1 26.0 45.7 50.2 70.6 41.4 63.7 38.8 38.6 46.1 61.5 60.2 43.5 55.7 35.0 43.2 55.0 34.8 58.3 35.7 57.1 38.3 46.5 50.1 36.6 34.2 34.9 57.0 46.1 46.9 46.4 71.6 29.4 25.3 33.3 35.5 33.2 89.9 53.6 34.5 46.0 36.8 47.4 45.0 84.5 36.0 43.7 76.2 33.3 23.2 29.5 58.7 58.2 49.5 67.5 37.9 46.6 62.3 58.9 11.9 5.1 8.5 4.1 5.3 4.4 6.9 6.4 6.2 6.3 4.3 5.9 4.8 4.1 4.0 5.5 9.6 4.9 2.8 9.8 10.3 11.7 15.9 9.7 10.6 10.1 11.4 10.2 9.7 10.9 12.1 17.3 19.2 21.5 14.7 26.9 18.7 27.9 27.5 19.9 15.3 28.5 20.6 29.2 18.6 23.2 25.8 22.9 42.0 35.3 19.9 29.4 22.0 6.9 28.8 35.8 19.3 13.2 29.9 29.6 27.1 80.4 24.8 34.7 23.7 41.3 15.4 21.8 19.8 22.3 8.4 30.6 27.9 32.6 17.2 18.4 9.9 24.2 16.8 14.2 19.7 21.2 14.9 15.5 22.1 23.3 19.0 16.7 22.2 51.8 34.7 16.9 21.3 27.7 24.7 26.3 17.5 21.4 11.0 14.9 26.6 21.5 51.6 23.4 20.9 23.2 28.6 SLC30A9 "C4orf1, GAC63, HUEL, ZNT9" ENSG00000014824 "Solute carrier family 30 member 9" Q6PML9 4 41990502-42090461 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transcription, Transcription regulation, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004014 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "HPA004014: AB_1080005" "unprognostic (4.26e-2)" "unprognostic (2.20e-1)" "unprognostic (1.31e-3)" "unprognostic (1.44e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.19e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-2)" "unprognostic (1.43e-1)" "unprognostic (1.55e-1)" "unprognostic (6.99e-2)" "prognostic favorable (2.86e-14)" "unprognostic (4.67e-2)" "unprognostic (1.34e-1)" "unprognostic (2.22e-2)" "unprognostic (1.39e-2)" 8.8 15.4 11.4 6.9 12.4 5.8 13.8 12.0 16.1 11.8 12.2 13.4 12.6 10.3 16.0 9.3 9.9 8.6 21.1 12.8 11.9 30.5 14.2 8.9 7.4 11.1 11.3 11.1 12.9 22.7 14.6 9.4 11.6 13.6 13.9 19.8 12.2 10.0 14.7 9.6 11.6 8.5 10.9 7.9 12.9 6.8 11.5 9.1 17.3 20.5 7.8 9.5 8.0 11.7 12.7 6.2 20.3 23.2 15.3 21.3 11.4 17.3 20.8 14.8 17.5 6.4 16.2 13.0 12.2 20.0 19.1 6.3 17.3 14.3 21.1 4.4 10.2 14.9 10.7 10.9 27.1 20.8 10.3 17.0 14.4 12.7 16.5 23.8 16.3 12.9 20.4 6.0 26.2 6.1 12.0 19.6 15.6 19.7 8.5 5.9 18.4 10.8 30.2 10.6 22.5 25.3 12.3 13.5 15.9 14.3 17.2 15.5 17.7 17.4 10.1 17.6 20.3 11.9 9.5 12.3 23.8 17.4 15.5 3.1 1.8 1.0 1.2 2.3 1.3 1.3 1.3 1.5 2.5 1.1 1.7 1.4 0.8 2.1 1.9 1.8 1.6 1.4 11.4 12.4 12.0 16.1 12.8 11.9 11.1 11.3 11.6 10.9 11.5 11.7 19.7 48.1 44.5 48.3 26.5 15.2 22.8 24.7 24.5 34.9 30.3 16.9 90.7 32.9 33.8 38.6 25.0 44.4 11.4 33.8 103.7 35.9 7.1 27.3 29.2 22.1 33.5 32.2 70.0 36.4 34.0 27.7 37.8 26.8 34.2 33.3 21.4 25.4 24.2 50.5 74.7 36.7 30.5 22.2 21.1 8.7 20.8 23.8 24.9 43.1 28.0 29.7 9.2 63.3 84.7 34.3 17.4 22.6 35.8 27.1 25.5 111.7 43.6 39.3 6.6 29.3 28.1 16.1 18.0 40.8 22.7 49.4 21.2 44.8 38.3 24.2 SLC35A3 ENSG00000117620 "Solute carrier family 35 member A3" Q9Y2D2 1 99969351-100035634 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015253 Uncertain NA NA "Cluster 6: Non-specific - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA015253: AB_1857106" "unprognostic (1.05e-1)" "unprognostic (2.69e-1)" "unprognostic (1.57e-3)" "unprognostic (5.89e-2)" "unprognostic (9.64e-2)" "unprognostic (1.61e-1)" "unprognostic (1.72e-1)" "unprognostic (4.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (1.76e-3)" "unprognostic (1.69e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (2.73e-2)" "unprognostic (9.34e-2)" 11.6 7.3 4.3 10.4 5.1 11.4 18.3 6.6 5.8 19.1 10.0 53.3 49.7 9.6 11.4 14.4 13.1 13.5 5.5 4.1 4.7 21.3 37.3 11.5 8.0 4.7 4.6 8.1 11.5 19.8 4.8 10.2 5.1 23.0 53.8 6.9 22.0 11.6 4.9 10.8 41.4 8.8 4.5 7.9 33.4 2.8 4.9 18.9 24.9 6.1 8.9 10.5 10.2 6.3 28.3 7.6 6.7 7.1 14.8 12.9 26.7 24.5 14.8 9.4 13.6 4.9 15.1 15.1 30.0 14.3 13.3 16.0 12.7 11.0 21.6 18.7 9.4 13.7 10.7 11.8 9.2 22.1 1.6 6.8 12.1 11.5 22.2 11.3 11.1 11.9 23.0 21.9 19.3 7.1 14.6 11.4 8.2 16.0 24.9 4.5 20.4 9.4 17.1 16.0 8.6 4.8 17.0 32.3 13.7 6.2 19.7 16.6 13.0 14.3 13.0 32.0 13.3 12.9 16.2 11.2 23.0 13.5 6.1 4.4 2.1 1.1 2.2 2.1 2.5 2.5 2.2 2.6 1.7 1.8 2.7 2.3 0.6 4.3 1.7 5.0 2.8 1.9 4.3 5.1 6.6 5.8 4.1 4.7 4.7 4.6 5.1 4.5 4.9 6.3 23.5 80.1 28.6 12.4 17.8 25.0 21.6 30.5 18.8 15.7 33.9 15.4 8.8 27.1 50.5 55.2 20.9 19.4 51.4 211.0 7.9 18.1 4.4 49.4 22.4 20.5 19.8 9.7 24.4 15.3 30.5 17.0 43.3 46.3 17.1 19.5 20.7 49.3 14.2 10.1 26.6 110.6 22.4 17.8 17.1 2.1 13.4 14.2 8.8 23.4 18.0 19.0 14.4 30.2 46.7 21.7 82.8 13.2 25.6 43.3 112.4 25.3 92.6 25.1 6.6 14.4 17.7 16.2 8.3 21.2 29.7 23.3 23.8 12.8 116.4 48.4 SLC39A9 FLJ11274 ENSG00000029364 "Solute carrier family 39 member 9" Q9NUM3 14 69398015-69462390 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007921, HPA075390" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 27: Mucus-secreting cells - Mucin production" "Endoplasmic reticulum" "HPA007921: AB_1080007, HPA075390: AB_2686748" "unprognostic (2.37e-1)" "unprognostic (9.29e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (4.35e-2)" "unprognostic (1.10e-1)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.05e-6)" "unprognostic (1.20e-1)" "unprognostic (1.83e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" 15.2 21.6 17.3 12.1 17.5 10.7 24.4 17.7 24.6 18.2 20.9 20.3 21.5 14.8 25.6 23.1 15.6 14.3 12.2 17.4 18.9 29.8 43.0 15.6 12.7 17.0 17.3 13.7 28.5 26.4 22.8 17.7 17.0 19.0 21.5 12.7 33.8 15.1 7.9 18.3 19.4 15.5 18.7 16.0 21.8 8.9 18.3 18.0 22.2 11.6 17.8 15.3 15.3 20.1 55.0 46.3 26.9 28.7 46.2 34.6 25.1 31.9 40.2 30.7 34.8 35.4 49.7 49.3 23.8 39.8 14.2 45.3 30.9 30.5 37.4 31.9 17.0 28.9 23.0 24.8 36.0 20.9 38.1 30.3 50.3 27.1 40.5 30.6 30.8 38.1 22.2 44.2 32.5 33.6 33.0 26.1 20.9 47.7 31.2 32.8 37.6 30.3 40.9 56.1 28.3 46.1 32.2 55.1 22.2 20.2 76.9 37.8 30.4 50.8 36.2 22.1 24.6 48.8 27.4 36.6 47.1 25.4 42.0 11.2 10.3 9.4 7.9 9.7 8.1 6.9 6.8 7.7 11.3 4.8 6.7 7.0 8.7 6.8 9.4 5.9 5.5 6.8 17.3 17.5 17.7 24.6 17.4 18.9 17.0 17.3 17.0 18.7 18.3 20.1 13.3 19.2 12.6 37.9 13.4 12.1 8.0 19.2 17.1 8.4 27.7 14.1 7.9 18.6 18.0 16.5 6.2 14.1 7.3 42.8 5.9 15.0 16.2 16.0 16.1 17.0 29.4 15.4 31.0 25.1 17.3 14.3 22.4 17.8 12.0 13.8 22.1 67.7 15.9 10.1 30.9 30.3 14.2 24.5 8.7 22.4 13.1 13.8 7.2 24.4 16.4 9.5 12.3 30.2 37.0 28.6 22.4 12.8 18.6 18.7 34.6 15.8 24.6 11.2 6.6 12.6 12.0 13.9 9.2 18.3 12.5 17.8 9.2 14.2 25.7 20.2 SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 102.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA065396: , HPA073994: " "unprognostic (9.60e-2)" "prognostic favorable (4.27e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (9.88e-2)" "unprognostic (1.54e-2)" "unprognostic (6.63e-3)" "prognostic favorable (1.34e-6)" "unprognostic (1.45e-1)" "unprognostic (5.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" 27.5 37.4 98.8 6.9 131.6 12.3 27.6 116.7 104.3 26.8 58.5 26.8 7.4 20.2 16.2 28.9 28.4 15.4 29.0 96.2 99.8 44.1 15.2 22.3 7.0 125.5 127.0 53.1 19.5 29.4 17.7 17.7 113.4 20.4 10.6 11.2 20.2 22.7 29.9 22.0 14.3 16.6 103.2 25.8 22.1 9.9 126.8 7.9 52.6 21.5 8.2 27.6 22.6 135.6 11.9 36.3 5.7 42.8 36.4 15.5 12.3 8.3 18.3 7.8 8.0 11.7 31.0 7.2 102.7 23.3 15.5 45.4 7.3 9.6 6.0 59.1 6.8 49.4 30.4 16.1 20.8 13.3 27.9 9.2 19.3 11.2 13.6 40.6 22.1 20.0 13.1 28.3 5.1 24.7 6.5 13.7 3.9 21.9 17.1 6.0 1.6 39.0 31.5 31.3 7.3 3.3 11.0 13.8 7.8 10.2 46.0 12.2 12.3 10.9 14.3 21.1 6.0 21.6 14.3 2.2 14.2 62.8 6.7 0.1 17.9 12.4 5.2 13.5 4.7 10.4 6.4 5.5 12.9 9.9 7.7 6.4 36.7 2.0 7.7 2.6 5.5 6.3 98.8 131.6 116.7 104.3 96.2 99.8 125.5 127.0 113.4 103.2 126.8 135.6 35.2 9.6 13.5 35.3 6.2 6.6 9.7 6.4 22.2 11.1 15.5 15.2 16.4 20.0 5.5 51.5 2.1 9.5 2.3 9.0 23.5 10.4 8.5 10.9 6.2 22.3 8.4 53.0 9.1 9.8 2.3 15.6 4.6 18.0 1.3 16.4 16.8 11.8 24.1 15.2 8.3 13.5 6.1 18.0 9.9 12.5 32.6 14.1 5.4 8.4 28.4 26.8 2.1 11.1 100.3 6.6 5.2 23.0 10.1 12.9 9.2 34.9 2.3 11.2 6.6 11.9 11.6 4.1 10.5 20.9 11.9 3.6 3.3 18.0 7.5 11.6 SLC4A4 "hhNMC, HNBC1, NBC1, NBC2, pNBC, SLC4A5" ENSG00000080493 "Solute carrier family 4 member 4" Q9Y6R1 4 71062667-71572087 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 119.5;pancreas: 260.3" "Cell type enhanced" "Detected in many" "Astrocytes: 819.1;Cholangiocytes: 133.0;Distal enterocytes: 282.9;Ductal cells: 129.2;Proximal tubular cells: 211.0" "Group enriched" "Detected in many" 5 "glioma: 23.9;pancreatic cancer: 22.5;prostate cancer: 47.4;renal cancer: 19.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 13.0;fHDF/TERT166: 6.1;HBF TERT88: 5.7;hTERT-RPE1: 6.0;RPTEC TERT1: 15.4;U-138 MG: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022493, HPA035628, HPA035629, HPA079220" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB022493: , HPA035628: AB_2674708, HPA035629: AB_2674709, HPA079220: " "unprognostic (3.92e-2)" "unprognostic (1.63e-1)" "prognostic favorable (7.69e-4)" "unprognostic (5.32e-2)" "unprognostic (1.01e-1)" "unprognostic (5.09e-2)" "unprognostic (4.24e-2)" "unprognostic (7.49e-2)" "unprognostic (1.46e-1)" "unprognostic (9.22e-3)" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.18e-4)" "unprognostic (7.00e-2)" "unprognostic (2.92e-1)" "unprognostic (2.05e-3)" "unprognostic (2.04e-1)" 5.1 0.7 30.0 2.2 43.6 0.5 1.0 47.0 32.5 11.5 0.0 41.1 54.3 0.4 0.3 1.2 0.9 29.4 6.2 21.5 37.9 119.5 21.7 6.9 0.2 38.6 28.0 0.8 260.3 17.2 5.8 2.7 24.8 34.7 41.2 5.1 2.5 1.1 2.2 0.1 14.6 1.7 38.2 0.8 18.6 0.5 38.5 3.5 22.0 3.5 0.0 4.5 0.4 33.2 0.0 3.5 1.0 0.0 0.0 0.0 0.1 13.0 1.9 2.2 1.6 0.0 0.1 0.0 0.1 6.1 0.5 0.0 0.2 0.0 5.7 0.0 1.7 0.9 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 6.0 0.0 0.7 0.0 0.5 1.2 0.0 4.8 0.2 0.1 0.2 0.0 0.0 0.0 0.9 15.4 4.1 0.9 0.1 0.0 0.0 0.2 1.3 0.0 0.0 0.0 7.7 0.7 5.5 0.6 0.0 0.0 0.0 5.1 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 30.0 43.6 47.0 32.5 21.5 37.9 38.6 28.0 24.8 38.2 38.5 33.2 1.5 3.2 37.1 819.1 2.2 0.0 4.3 3.2 0.6 3.2 0.9 0.3 24.0 133.0 31.1 25.8 0.0 0.3 7.2 282.9 15.6 129.2 11.5 2.8 0.5 1.3 8.5 4.0 51.4 24.2 0.1 4.9 33.1 5.8 1.3 0.6 3.9 35.8 0.2 0.0 93.4 65.6 2.0 0.6 0.2 1.5 0.0 2.3 1.8 34.7 1.0 3.9 1.0 29.1 3.7 16.2 60.8 0.0 1.7 40.8 31.8 211.0 10.4 1.5 6.6 1.0 6.2 0.1 1.0 5.5 0.0 0.3 6.8 2.4 68.1 12.3 SLC5A8 AIT ENSG00000256870 "Solute carrier family 5 member 8" Q8N695 12 101155493-101210238 "Metabolic proteins, Predicted membrane proteins, Transporters" "Apoptosis, Ion transport, Sodium transport, Symport, Transport" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 20.3;kidney: 5.6;thyroid gland: 15.5" "Cell type enhanced" "Detected in some" "Club cells: 9.1;Early spermatids: 7.9;Enteroendocrine cells: 31.5;Excitatory neurons: 14.6;Horizontal cells: 10.1;Inhibitory neurons: 17.3;Proximal tubular cells: 21.4" "Group enriched" "Detected in many" 4 "breast cancer: 2.7;renal cancer: 7.6;thyroid cancer: 5.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "SK-BR-3: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "prognostic favorable (9.04e-6)" "unprognostic (1.84e-1)" "unprognostic (1.17e-2)" "unprognostic (1.27e-3)" "unprognostic (1.24e-1)" "unprognostic (5.20e-1)" "unprognostic (1.16e-2)" "prognostic favorable (1.97e-4)" "unprognostic (6.16e-2)" "unprognostic (2.30e-2)" "unprognostic (2.87e-2)" 0.0 2.4 0.5 0.0 0.5 0.0 0.0 0.3 1.2 20.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 5.6 0.0 0.9 0.0 0.9 0.3 1.0 0.0 0.0 0.1 0.0 0.5 0.8 0.0 0.1 0.9 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.2 1.5 0.2 15.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.4 0.8 0.9 0.3 0.5 0.5 1.5 0.8 0.0 0.0 5.3 1.3 0.0 0.0 0.0 4.6 0.0 3.9 0.1 0.1 0.6 0.0 9.1 1.8 0.0 0.0 0.0 0.3 1.9 0.0 7.9 0.0 0.1 0.0 31.5 0.0 14.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 17.3 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.6 0.2 21.4 2.1 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.9 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SLC7A8 "LAT2, LPI-PC1" ENSG00000092068 "Solute carrier family 7 member 8" Q9UHI5 14 23125295-23183674 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 331.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 74.1;Kupffer cells: 90.0;Proximal tubular cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 9.3;eosinophil: 14.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 14.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.8;BEWO: 110.6;K-562: 136.9;NTERA-2: 64.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046015, HPA051950, HPA060672" Enhanced NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB046015: AB_2239464, HPA051950: AB_2681670, HPA060672: AB_2684340" "unprognostic (1.50e-1)" "unprognostic (1.52e-1)" "unprognostic (2.88e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-2)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.97e-4)" "prognostic favorable (3.15e-4)" "unprognostic (1.24e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-3)" "unprognostic (9.44e-2)" "unprognostic (7.00e-2)" "unprognostic (2.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.52e-4)" 27.6 15.2 1.2 7.0 7.1 1.6 27.7 5.5 7.6 31.3 42.8 12.5 36.3 43.6 4.8 37.5 45.9 18.6 7.9 3.4 6.5 119.3 6.9 15.4 4.5 3.4 3.1 67.5 19.9 331.1 15.8 16.0 5.8 39.2 13.7 13.9 23.8 35.5 49.4 31.6 24.2 20.9 0.0 18.5 63.4 21.2 6.7 4.9 23.7 15.4 9.0 29.9 37.5 1.4 1.6 0.0 52.9 0.1 68.8 8.5 110.6 6.0 26.3 0.3 2.0 60.4 3.6 0.4 0.8 13.9 5.4 11.7 8.5 3.5 0.3 0.0 5.2 0.6 0.3 0.0 25.5 0.2 35.8 54.1 33.2 0.9 0.9 11.6 5.2 5.4 136.9 0.3 1.5 1.2 0.3 0.8 64.0 12.9 47.4 0.1 0.9 12.5 0.7 21.4 8.2 0.3 0.2 12.0 32.3 60.1 42.8 0.6 0.5 2.3 1.8 0.7 0.0 0.3 15.9 0.2 6.9 0.0 0.4 9.3 0.1 14.0 0.0 0.1 1.1 0.1 0.9 0.1 0.0 0.0 0.9 3.3 0.4 0.0 0.1 0.0 0.5 2.3 1.2 7.1 5.5 7.6 3.4 6.5 3.4 3.1 5.8 0.0 6.7 1.4 0.5 16.0 15.0 2.3 1.8 3.1 28.8 6.4 29.0 26.4 31.6 15.2 5.7 0.0 9.0 16.5 0.0 18.7 0.5 8.3 5.9 1.9 2.2 13.6 74.1 2.1 33.0 0.0 24.8 2.4 4.4 15.5 53.5 18.4 5.1 27.3 66.4 1.3 59.2 26.9 53.5 33.7 4.1 90.0 3.3 3.1 9.6 15.3 19.6 15.9 0.5 39.3 0.0 4.0 2.6 3.0 6.5 7.9 1.6 26.4 27.3 144.8 1.0 4.4 0.0 2.8 4.7 1.1 1.3 25.3 3.0 41.3 2.9 3.4 18.5 32.3 SLIT2 "SLIL3, Slit-2" ENSG00000145147 "Slit guidance ligand 2" O94813 4 20251905-20620561 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 256.7;Inhibitory neurons: 544.9;Oligodendrocytes: 157.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.0;BJ hTERT+: 200.8;BJ hTERT+ SV40 Large T+: 97.8;fHDF/TERT166: 117.8;HBF TERT88: 112.0;HEK 293: 88.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007590, HPA019511, HPA023088" Uncertain "Secreted in other tissues" NA NA 77000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB007590: , HPA019511: AB_1857226, HPA023088: AB_1857227" "unprognostic (1.44e-1)" "unprognostic (4.54e-2)" "unprognostic (3.26e-2)" "unprognostic (6.13e-2)" "unprognostic (9.01e-3)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (4.78e-2)" "unprognostic (1.73e-1)" "unprognostic (6.16e-3)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "prognostic favorable (6.51e-4)" "unprognostic (4.93e-3)" "unprognostic (6.80e-3)" "unprognostic (1.74e-1)" "unprognostic (7.16e-4)" 8.0 24.9 3.2 3.3 6.4 0.0 9.4 0.0 14.0 24.0 11.7 11.5 2.4 16.4 9.9 5.8 13.1 9.4 7.8 6.6 20.5 12.3 2.0 34.9 1.8 7.9 3.1 4.3 2.8 1.5 8.8 25.2 4.5 12.6 5.4 13.2 6.1 15.7 2.9 3.8 4.8 24.9 0.4 14.2 9.0 1.3 17.6 2.4 9.2 5.1 1.2 13.1 13.9 2.4 0.1 0.0 54.6 0.0 37.8 34.8 1.7 98.0 200.8 97.8 36.9 0.4 0.1 0.0 3.4 117.8 0.2 1.2 15.7 7.9 112.0 0.2 88.3 0.0 0.4 0.0 7.2 0.9 0.0 8.5 0.0 63.6 18.6 2.1 35.0 0.0 0.0 0.0 4.6 0.0 0.0 0.4 1.7 0.0 6.3 61.2 0.5 0.0 1.0 0.1 3.5 0.8 0.0 0.2 0.4 1.9 0.2 0.2 2.0 34.9 5.0 35.0 54.2 0.0 0.1 0.0 0.9 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 6.4 0.0 14.0 6.6 20.5 7.9 3.1 4.5 0.4 17.6 2.4 1.6 0.0 9.0 10.1 0.0 8.0 2.0 0.1 0.6 47.6 1.0 0.6 5.2 1.5 1.3 0.0 0.0 1.1 0.0 0.6 1.9 1.7 0.6 6.4 1.9 2.0 1.2 0.0 256.7 0.5 1.2 58.8 0.0 7.1 2.5 1.3 4.2 0.2 1.9 0.0 544.9 0.0 0.0 1.0 9.7 1.7 26.4 0.7 8.8 31.9 0.0 1.3 0.0 43.7 157.9 0.2 0.0 26.7 0.1 3.7 0.0 11.5 7.4 2.1 6.6 3.2 6.4 0.2 1.7 1.2 6.7 2.1 1.1 20.3 0.1 1.9 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 48.6 52.6 38.0 38.6 42.4 37.5 46.5 46.2 36.7 43.2 35.6 47.5 36.7 38.6 41.0 55.0 46.8 39.6 53.8 32.9 48.6 43.3 35.6 46.7 44.5 50.2 43.2 52.5 40.4 44.6 20.3 42.7 51.9 36.4 48.7 70.5 36.7 44.8 57.4 34.0 37.4 47.9 47.8 47.5 45.2 51.5 42.4 72.4 75.7 55.5 55.2 53.8 31.1 59.4 81.1 113.7 68.0 66.2 106.1 128.5 77.4 86.1 102.7 87.9 101.8 43.8 75.6 124.8 60.3 110.0 123.0 86.6 77.2 96.1 116.9 136.4 39.3 106.4 164.4 71.9 123.2 149.6 104.1 95.8 121.4 75.5 172.9 102.1 98.6 99.7 50.3 101.6 109.6 52.7 103.4 71.6 33.6 4.4 26.7 74.4 98.9 85.9 197.8 137.2 62.8 73.3 103.7 70.1 85.7 65.8 53.5 97.7 111.4 129.5 74.2 35.6 63.6 99.0 102.7 108.3 89.6 99.9 97.1 58.8 33.6 38.7 23.8 38.5 29.8 16.7 32.3 29.9 32.8 13.9 35.3 27.6 34.1 38.6 33.0 23.3 40.5 31.6 38.0 42.4 46.2 36.7 32.9 48.6 50.2 43.2 51.9 47.8 42.4 59.4 55.0 44.8 36.1 55.8 36.3 54.4 44.1 38.3 54.1 48.0 44.2 30.2 49.2 41.5 45.5 77.3 212.7 48.2 53.0 42.8 39.2 36.5 68.1 58.6 53.0 53.1 51.0 36.4 63.4 43.5 40.3 40.5 44.4 68.1 21.5 80.0 56.4 29.6 43.9 35.3 50.5 46.1 38.7 57.3 41.8 131.9 41.7 48.7 51.6 104.9 63.9 44.8 72.1 96.0 130.0 44.0 31.6 53.4 34.5 66.1 37.9 39.5 41.8 88.1 32.9 53.5 39.6 37.2 39.4 59.2 61.8 69.5 47.4 41.7 42.3 77.2 SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" 12.2 13.9 21.6 6.1 22.2 17.6 19.5 25.7 27.7 14.6 21.2 14.7 10.3 12.3 19.5 12.6 15.2 7.4 20.0 22.1 22.0 18.2 15.1 9.7 16.1 21.6 21.4 22.5 21.5 18.0 14.9 7.3 22.2 16.1 11.2 16.0 22.7 13.4 35.6 14.8 13.5 8.4 21.3 12.6 17.7 6.9 21.3 12.4 18.6 37.9 12.2 12.4 11.9 22.4 5.7 3.7 7.4 8.9 13.1 9.5 5.8 2.0 10.0 12.1 10.5 7.1 5.3 7.8 2.4 10.3 3.4 6.1 9.8 10.4 7.7 3.8 15.7 4.7 8.1 10.3 16.5 8.6 5.9 7.4 17.3 4.8 9.9 6.9 12.2 5.1 7.9 12.3 8.4 11.2 12.1 13.0 2.8 14.1 2.7 10.8 6.5 20.8 15.5 6.4 9.2 6.0 5.0 11.1 12.8 3.7 9.3 9.3 4.8 5.1 5.3 4.5 3.9 8.2 9.8 16.9 7.9 8.5 4.1 4.0 5.8 2.9 3.1 3.1 5.9 5.9 8.6 4.5 8.4 7.2 9.3 6.0 0.5 5.5 4.5 6.4 5.4 5.4 21.6 22.2 25.7 27.7 22.1 22.0 21.6 21.4 22.2 21.3 21.3 22.4 161.1 83.3 109.3 11.8 295.0 166.7 202.2 157.3 191.2 71.6 400.9 477.3 350.9 237.4 160.3 204.1 20.9 308.7 127.8 285.6 573.2 160.0 114.0 156.8 81.1 138.2 345.2 135.7 10.5 199.6 190.6 127.8 150.3 127.2 91.4 55.4 161.3 380.1 256.1 55.5 12.8 356.5 262.4 164.5 200.6 131.9 189.2 187.7 211.7 5.6 125.8 196.4 124.6 7.5 13.8 193.7 314.0 149.0 275.8 238.2 486.7 623.4 223.7 109.5 124.9 133.6 202.7 256.0 55.5 271.5 274.1 308.8 186.3 151.7 308.8 272.2 SMIM10L1 ENSG00000256537 "Small integral membrane protein 10 like 1" P0DMW3 12 11171194-11176016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" "unprognostic (2.27e-1)" "unprognostic (5.11e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-2)" "unprognostic (3.49e-2)" "unprognostic (1.36e-1)" "unprognostic (2.97e-3)" "unprognostic (3.14e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.71e-4)" "unprognostic (2.80e-2)" "unprognostic (2.78e-1)" "prognostic unfavorable (3.56e-4)" "unprognostic (8.37e-2)" "unprognostic (1.38e-1)" "unprognostic (1.45e-1)" "prognostic favorable (9.70e-4)" 5.9 16.1 12.0 4.8 12.1 5.8 4.9 11.3 15.5 4.4 11.8 9.8 5.2 6.7 7.9 4.2 4.6 3.5 14.4 12.4 12.5 7.5 10.6 4.7 4.7 12.3 12.5 3.8 4.8 5.6 8.8 4.8 12.3 6.6 4.5 7.3 11.5 6.2 21.7 2.7 5.9 5.5 13.0 6.1 6.4 3.2 12.4 6.2 6.0 10.2 4.0 6.9 3.9 12.6 10.5 6.3 16.6 7.3 13.2 9.6 14.5 15.4 9.2 9.9 7.7 13.3 9.2 8.7 6.7 8.7 12.6 6.8 9.9 7.7 12.6 30.3 11.7 15.9 9.2 12.9 9.1 22.4 5.1 8.5 6.7 10.1 10.1 11.8 8.1 14.5 11.6 7.7 11.4 10.1 15.7 18.6 26.9 5.7 8.1 13.0 19.8 9.3 12.5 11.9 8.8 9.7 12.5 7.6 23.0 27.0 4.1 15.1 9.9 17.7 25.1 7.7 15.5 6.6 14.5 21.3 12.9 13.0 16.3 22.1 9.7 11.4 8.9 8.3 9.6 6.1 9.3 9.4 7.9 7.4 10.3 8.5 1.2 12.8 7.9 9.6 10.4 9.0 12.0 12.1 11.3 15.5 12.4 12.5 12.3 12.5 12.3 13.0 12.4 12.6 33.8 16.0 27.4 0.0 25.6 0.0 15.3 0.0 23.3 26.7 33.6 38.2 88.4 35.8 18.0 7.3 25.0 56.7 47.3 9.3 52.8 48.7 5.2 33.1 26.0 36.1 12.2 40.0 0.0 50.7 23.9 28.0 17.3 21.0 16.4 24.9 29.3 34.9 43.8 26.9 0.0 18.5 0.0 25.8 0.0 9.9 26.4 26.8 0.0 0.0 38.5 29.5 56.7 0.0 0.0 52.7 13.3 32.4 41.8 23.4 38.0 68.1 16.8 34.4 32.9 22.9 33.6 11.5 22.0 19.8 0.0 17.9 30.7 46.8 17.3 11.1 SMIM15 "C5orf43, DKFZP686E2158" ENSG00000188725 "Small integral membrane protein 15" Q7Z3B0 5 61157704-61162468 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (1.18e-1)" "unprognostic (2.56e-1)" "unprognostic (2.33e-2)" "unprognostic (3.82e-1)" "unprognostic (3.32e-2)" "unprognostic (6.03e-2)" "unprognostic (9.83e-3)" "unprognostic (4.43e-2)" "unprognostic (2.44e-2)" "unprognostic (4.09e-1)" "unprognostic (5.08e-2)" "unprognostic (1.72e-1)" "unprognostic (5.34e-3)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (1.89e-1)" "prognostic favorable (9.23e-4)" 19.0 23.6 13.5 24.6 14.7 22.5 29.1 14.4 17.2 26.9 12.0 49.1 42.6 22.3 23.4 32.5 30.9 25.1 15.8 12.8 15.2 31.8 43.3 24.3 26.8 14.1 13.7 33.1 27.5 36.4 16.1 30.3 14.6 30.7 41.4 21.4 27.1 27.7 11.2 18.5 40.8 23.7 15.6 19.5 46.6 15.3 13.6 27.7 35.6 15.6 28.9 40.3 21.5 17.7 95.3 79.6 51.4 84.1 48.8 58.0 52.9 78.5 86.0 77.1 103.2 69.4 141.4 46.2 133.4 82.6 101.3 54.5 0.0 94.3 90.3 97.4 42.1 72.9 60.7 67.9 95.4 54.2 65.9 69.0 85.9 95.7 108.6 58.9 62.9 57.1 87.0 61.7 87.4 99.5 27.9 0.7 63.4 38.7 92.7 9.8 63.8 106.2 83.3 112.6 71.0 67.9 90.4 48.2 99.4 35.9 90.9 58.3 72.4 46.1 73.9 58.9 100.9 62.6 117.3 85.9 63.2 29.6 96.7 33.2 56.4 20.2 34.7 70.5 38.7 41.6 38.3 39.9 51.4 33.9 46.0 32.1 11.3 58.8 57.8 41.2 55.9 39.4 13.5 14.7 14.4 17.2 12.8 15.2 14.1 13.7 14.6 15.6 13.6 17.7 26.8 57.7 37.1 4.9 39.4 86.8 122.1 58.1 60.3 25.7 45.2 33.4 21.2 35.8 53.2 42.3 8.4 71.9 34.6 79.9 135.0 70.8 23.3 35.6 40.3 25.7 55.2 29.2 3.9 61.3 62.9 50.0 57.1 40.9 23.5 35.4 25.7 40.4 73.4 40.4 4.3 74.0 42.7 40.8 30.5 24.5 46.3 40.5 40.9 2.8 33.8 59.3 44.3 4.5 8.7 75.2 116.1 42.2 41.9 108.6 73.2 93.0 37.0 20.8 26.3 28.2 37.6 18.7 12.3 78.6 82.7 47.5 34.9 45.7 82.8 152.6 SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" 55.2 57.1 34.7 18.4 35.4 32.5 64.9 35.8 44.3 31.9 35.8 41.7 30.0 32.6 80.0 33.2 57.0 27.8 59.6 36.1 35.8 76.9 136.8 31.5 36.9 34.2 34.9 42.2 68.5 36.2 26.8 23.3 35.1 31.9 34.6 21.1 62.6 30.1 121.8 44.8 38.9 25.1 35.7 33.3 46.2 43.9 35.0 36.6 73.5 74.1 33.9 36.4 29.9 37.3 38.9 28.5 61.0 52.6 35.9 43.2 19.9 29.9 40.2 23.4 27.8 6.8 84.4 42.4 12.2 25.1 57.0 27.2 31.8 19.2 24.3 33.8 26.3 35.9 17.9 15.5 73.9 25.7 9.0 35.4 16.1 19.6 62.7 45.3 21.5 49.1 28.8 94.5 23.7 38.0 18.8 39.0 72.1 90.4 19.5 21.1 43.4 72.4 60.7 28.5 12.7 46.0 30.0 32.2 93.1 32.6 68.0 48.2 27.3 14.7 12.5 40.8 19.6 88.7 53.8 56.9 62.2 40.9 39.6 92.2 42.3 31.4 46.3 34.0 56.5 71.3 59.6 57.0 65.1 68.3 55.6 54.3 15.3 80.7 28.8 107.2 78.2 40.0 34.7 35.4 35.8 44.3 36.1 35.8 34.2 34.9 35.1 35.7 35.0 37.3 53.1 22.4 45.9 5.9 43.0 45.8 63.5 89.8 70.6 25.2 89.9 108.8 75.7 88.6 66.2 33.1 6.2 90.1 58.6 36.2 201.5 67.9 183.9 109.6 26.0 43.9 16.3 45.6 12.7 126.8 62.9 65.5 43.3 54.8 40.0 52.3 47.8 142.5 78.3 23.5 13.4 74.4 61.1 45.9 51.0 77.5 69.0 47.3 92.5 11.2 64.0 66.7 42.2 10.6 14.6 85.5 69.5 59.5 29.0 53.3 161.9 228.2 110.9 14.3 26.3 67.6 50.7 131.3 48.6 58.4 49.6 47.2 43.3 76.4 74.8 63.2 SMIM30 LINC00998 ENSG00000214194 "Small integral membrane protein 30" A4D0T7 7 113116718-113118560 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 126.9;Distal tubular cells: 414.8;Hofbauer cells: 243.9;Proximal tubular cells: 396.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.25e-1)" "unprognostic (1.73e-3)" "unprognostic (6.77e-2)" "unprognostic (1.04e-2)" "unprognostic (2.44e-3)" "unprognostic (3.89e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (7.25e-2)" "unprognostic (5.00e-3)" "unprognostic (7.07e-3)" "unprognostic (6.80e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.46e-2)" "unprognostic (1.82e-1)" "unprognostic (2.63e-1)" "unprognostic (1.35e-1)" 44.6 53.2 40.8 26.8 41.5 12.2 47.2 41.4 57.8 37.2 40.8 33.3 32.3 30.6 70.9 39.5 30.5 37.4 205.3 40.7 42.7 83.7 57.6 40.0 38.5 42.8 40.0 26.9 41.6 83.9 26.3 29.4 42.5 37.6 35.6 43.5 47.8 30.0 142.5 20.8 27.6 39.0 42.5 41.4 39.4 19.7 41.0 30.2 60.0 149.6 31.8 50.6 21.5 44.8 48.0 24.1 56.3 49.6 100.8 159.8 0.2 57.3 95.0 60.5 94.0 25.1 82.7 57.4 69.5 72.0 104.5 29.9 55.8 126.5 146.8 37.9 113.3 130.3 32.7 42.9 66.8 179.2 0.4 120.8 120.1 91.6 46.8 111.0 95.7 60.6 176.1 52.4 199.6 24.7 76.3 196.4 58.6 72.6 66.0 47.7 136.2 156.9 118.8 63.9 85.1 61.8 43.1 85.6 140.2 97.5 57.5 117.4 55.1 96.8 49.6 110.9 86.2 77.6 102.6 205.3 126.9 161.0 138.0 2.0 15.8 12.5 16.1 17.6 17.9 19.6 18.3 16.9 25.2 17.0 17.2 17.5 0.6 19.7 14.1 36.5 23.2 16.7 40.8 41.5 41.4 57.8 40.7 42.7 42.8 40.0 42.5 42.5 41.0 44.8 32.6 51.3 68.9 0.0 10.4 0.0 0.0 0.0 0.0 0.0 77.4 42.7 0.0 0.0 32.8 126.9 0.0 76.2 8.2 0.0 414.8 102.3 0.0 51.5 37.8 27.7 0.0 0.0 0.0 69.8 61.8 20.7 0.0 43.5 32.8 27.0 0.0 0.0 243.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 44.5 0.0 0.0 0.0 0.0 83.7 0.0 0.0 1.3 0.0 0.0 396.3 32.8 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 41.6 11.0 70.8 0.0 0.0 SMIM7 "C19orf42, MGC2747" ENSG00000214046 "Small integral membrane protein 7" Q9BQ49 19 16630751-16660442 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043127 Uncertain Approved "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "HPA043127: AB_10806378" "unprognostic (6.61e-2)" "unprognostic (1.61e-2)" "unprognostic (1.90e-1)" "unprognostic (3.71e-2)" "unprognostic (2.52e-1)" "unprognostic (2.28e-1)" "unprognostic (9.65e-2)" "unprognostic (1.79e-2)" "unprognostic (6.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-3)" "unprognostic (8.29e-3)" "unprognostic (2.94e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (7.64e-2)" 41.6 39.5 39.6 24.8 41.8 19.9 47.2 41.4 48.5 36.7 39.8 34.1 34.4 32.5 72.9 30.0 36.9 30.5 35.8 37.8 41.3 52.7 66.7 33.5 33.7 42.9 41.1 32.2 47.7 54.1 16.1 34.7 42.2 46.5 42.0 18.6 52.3 39.3 18.7 32.1 25.4 36.4 43.0 26.7 38.2 21.0 41.7 29.3 50.0 21.0 34.0 32.8 17.9 44.2 60.6 52.1 48.7 42.3 74.4 64.4 48.9 50.4 69.4 70.7 68.8 45.2 111.8 44.4 67.7 69.3 50.5 48.0 44.5 69.8 86.7 38.1 34.4 42.4 34.9 48.5 43.3 64.2 46.5 49.3 49.8 51.5 52.9 43.0 68.9 40.3 59.9 53.7 81.6 120.2 42.4 55.1 45.2 121.5 77.4 41.3 32.9 43.4 83.4 66.3 26.0 48.2 37.8 41.0 51.2 26.8 59.9 80.5 41.5 55.4 35.7 130.3 83.2 46.4 72.6 56.0 56.3 75.6 71.2 47.5 73.3 38.3 37.1 65.8 35.3 49.6 38.0 37.0 58.8 44.3 37.0 33.6 31.0 42.8 78.3 79.2 44.9 45.3 39.6 41.8 41.4 48.5 37.8 41.3 42.9 41.1 42.2 43.0 41.7 44.2 63.5 67.3 64.5 29.0 75.5 34.2 62.8 114.3 70.6 70.1 69.0 84.6 38.5 57.2 68.8 57.0 95.9 144.1 68.5 67.6 129.1 85.2 18.4 58.2 60.8 61.5 73.0 54.7 35.3 86.3 105.2 74.9 57.1 51.5 50.1 42.3 66.0 85.7 115.6 63.9 32.1 78.3 77.3 77.2 43.9 21.6 88.9 64.6 48.0 21.5 102.4 101.3 98.9 21.6 44.8 87.6 87.0 83.1 76.5 77.6 85.1 140.0 54.6 121.4 72.3 42.3 64.8 84.0 81.0 74.7 35.8 156.4 54.7 66.7 62.7 57.7 SNRPC "U1-C, Yhc1" ENSG00000124562 "Small nuclear ribonucleoprotein polypeptide C" P09234 6 34757505-34773857 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 384.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034338, HPA042419, HPA055490" Supported Enhanced Nucleoplasm NA NA 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "CAB034338: AB_2295245, HPA042419: AB_2677989, HPA055490: AB_2682833" "unprognostic (1.84e-1)" "unprognostic (3.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.32e-3)" "unprognostic (1.45e-1)" "unprognostic (3.93e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.48e-2)" "unprognostic (6.16e-2)" "unprognostic (1.16e-3)" "unprognostic (7.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (8.20e-5)" "unprognostic (4.39e-2)" "unprognostic (8.64e-2)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" 71.7 73.9 68.4 67.7 73.7 176.7 74.2 73.1 84.5 67.0 75.3 78.5 73.1 83.5 63.1 85.5 84.8 48.9 195.7 70.5 71.8 91.7 92.0 62.6 101.6 72.2 70.5 75.0 87.0 78.2 57.6 73.5 73.1 65.8 65.6 39.7 75.2 55.3 162.0 67.4 75.6 65.3 75.4 84.7 81.8 124.4 72.6 115.5 75.3 125.0 95.3 73.9 66.6 78.4 332.8 203.2 260.7 331.6 137.7 134.7 199.0 186.6 204.9 367.9 308.6 349.6 128.4 373.9 239.1 235.0 255.6 156.0 398.7 279.1 297.8 247.6 420.0 287.7 158.7 493.4 240.1 371.2 171.0 167.3 266.4 372.5 264.1 144.9 237.0 354.4 471.2 205.0 270.4 280.8 443.8 592.0 282.4 493.9 245.8 295.2 219.4 350.5 242.0 140.9 316.9 229.9 167.3 167.0 422.3 167.7 256.0 541.5 157.4 219.8 258.3 181.0 460.4 228.5 645.6 522.4 101.2 629.7 381.1 122.8 165.7 133.4 127.2 200.4 149.4 233.5 156.2 148.4 196.1 210.7 168.3 153.9 30.3 163.3 238.6 207.6 235.7 245.6 68.4 73.7 73.1 84.5 70.5 71.8 72.2 70.5 73.1 75.4 72.6 78.4 43.6 121.8 107.9 5.2 70.5 44.0 76.0 178.6 72.8 25.9 47.4 64.4 229.3 82.9 131.3 68.0 25.0 239.8 69.0 49.1 189.8 148.4 185.6 74.2 58.0 74.3 90.7 73.2 11.1 156.8 213.9 72.3 51.5 63.7 80.4 83.6 71.4 101.1 232.2 28.6 10.1 92.6 118.0 77.3 55.1 83.8 55.3 75.4 64.0 1.9 158.2 96.6 123.6 8.5 14.6 149.3 66.7 41.8 116.6 70.0 96.0 214.6 127.4 41.4 65.7 49.0 82.8 384.6 99.7 83.8 44.8 113.3 70.7 86.3 109.6 67.8 SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: AB_1080042" "unprognostic (3.30e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (4.44e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.52e-2)" "unprognostic (3.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" 30.5 31.1 24.7 35.2 25.7 39.2 37.5 29.6 34.8 31.8 25.7 50.5 33.2 35.5 35.5 43.5 36.7 20.2 35.3 25.0 25.8 48.0 64.9 26.9 47.7 23.7 23.9 34.3 23.7 51.2 27.0 24.7 25.5 33.8 40.7 54.1 29.7 31.9 103.7 28.8 35.7 29.5 23.6 34.3 36.5 24.7 25.0 74.4 38.9 86.2 53.3 39.5 32.3 30.7 182.5 45.7 188.6 58.5 70.1 57.7 56.1 173.1 74.8 166.1 148.1 61.4 65.8 158.7 70.1 109.2 83.0 130.7 252.1 219.3 175.5 107.9 188.8 152.4 95.4 113.9 66.2 408.0 95.7 66.5 93.8 186.3 86.6 81.8 120.6 139.8 116.2 60.5 61.5 56.8 187.0 82.6 98.9 237.8 61.9 179.5 190.7 66.6 154.5 130.0 82.2 95.6 83.4 62.7 87.7 162.7 102.3 97.5 135.5 127.0 126.3 74.3 126.2 74.3 168.2 283.7 70.1 127.1 91.4 18.5 42.9 53.9 35.6 50.2 37.6 60.5 38.4 39.2 54.2 50.7 36.6 41.3 18.6 51.1 51.1 49.7 41.1 47.4 24.7 25.7 29.6 34.8 25.0 25.8 23.7 23.9 25.5 23.6 25.0 30.7 120.0 96.1 81.8 7.5 118.2 108.6 115.3 293.1 133.1 61.1 94.2 138.8 95.9 101.5 162.9 130.6 35.5 239.5 123.1 112.6 291.6 161.9 91.0 176.6 157.7 96.8 111.0 139.4 8.1 114.8 228.8 121.0 92.2 147.9 86.2 145.3 66.0 203.3 176.4 38.7 8.7 134.2 168.9 74.5 84.8 85.1 116.2 98.1 67.6 10.3 151.0 134.3 86.5 8.0 13.4 129.4 118.2 118.5 120.7 96.8 191.7 310.5 135.2 68.9 65.7 102.8 209.6 111.1 131.4 164.9 113.7 180.3 111.9 176.2 139.0 113.3 SNU13 "15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1" ENSG00000100138 "Small nuclear ribonucleoprotein 13" P55769 22 41673933-41690504 "Predicted intracellular proteins, Ribosomal proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1057.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA029199 Uncertain NA NA 28000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "HPA029199: AB_10601041" "unprognostic (3.02e-1)" "unprognostic (4.82e-2)" "unprognostic (8.58e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (4.54e-2)" "unprognostic (1.94e-3)" "unprognostic (2.43e-1)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (3.46e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" "unprognostic (1.43e-1)" 64.9 125.6 156.5 74.5 157.7 135.7 80.7 146.4 159.5 81.8 134.4 77.8 64.9 64.6 99.0 65.5 91.2 55.7 145.1 159.1 191.3 75.7 65.2 61.9 97.4 159.5 159.4 96.7 74.8 113.6 52.7 67.5 173.3 65.8 73.5 85.5 74.8 70.9 187.1 73.3 56.1 71.4 150.1 71.2 66.3 94.9 173.3 98.2 90.1 178.0 108.4 88.7 34.0 151.9 222.8 100.2 151.8 203.7 192.7 173.5 160.1 212.6 181.4 303.0 259.6 215.1 195.0 148.6 165.5 183.6 91.6 160.3 183.6 239.0 205.5 178.1 428.0 163.0 191.1 313.1 249.5 345.3 217.9 157.7 247.0 226.6 330.2 142.1 175.2 161.2 227.3 244.8 200.6 262.7 238.0 369.7 215.6 852.4 240.8 252.7 126.7 505.5 279.6 128.9 135.9 125.0 102.4 249.4 333.7 160.6 116.8 218.1 125.1 152.6 175.3 191.0 166.8 273.7 366.5 353.6 206.9 195.5 218.1 205.5 224.8 210.8 210.5 233.3 225.3 357.4 252.0 226.6 240.3 311.2 266.1 247.4 67.5 205.3 208.5 288.2 346.2 339.9 156.5 157.7 146.4 159.5 159.1 191.3 159.5 159.4 173.3 150.1 173.3 151.9 217.9 80.1 121.9 0.0 265.1 0.0 390.5 0.0 196.9 160.1 224.4 272.3 0.0 190.1 65.0 185.8 25.0 367.3 205.8 42.1 655.4 310.0 1057.6 223.4 169.0 198.0 70.4 144.7 0.0 302.3 438.5 172.4 125.4 251.9 77.0 162.3 181.3 205.0 293.1 109.4 0.0 118.9 0.0 140.1 0.0 318.4 211.9 162.9 0.0 0.0 186.3 181.8 151.4 0.0 0.0 340.9 127.7 174.2 261.9 630.5 202.2 462.5 68.5 128.4 138.1 169.0 143.0 505.9 279.5 219.8 0.0 460.5 208.0 193.8 139.5 505.0 SNUPN "RNUT1, SNURPORTIN-1, Snurportin1" ENSG00000169371 "Snurportin 1" O95149 15 75598083-75626469 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 137.1;Spermatocytes: 93.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005004 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB005004: AB_425829" "unprognostic (2.37e-2)" "unprognostic (1.54e-1)" "unprognostic (2.36e-2)" "unprognostic (8.73e-2)" "unprognostic (2.25e-1)" "unprognostic (1.18e-1)" "unprognostic (4.76e-2)" "unprognostic (6.74e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.99e-3)" "unprognostic (9.07e-2)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (3.12e-1)" "unprognostic (2.14e-2)" 18.2 16.0 21.0 15.5 21.6 13.8 23.5 20.5 26.3 20.4 21.9 18.1 14.9 18.9 20.3 14.3 23.7 13.5 16.4 22.1 20.9 20.1 22.1 14.9 20.1 19.5 20.1 26.3 12.7 21.0 12.1 15.2 20.1 16.5 17.4 13.2 19.8 17.6 34.7 16.7 15.4 24.5 18.7 17.2 15.8 34.3 20.5 22.1 20.9 30.5 21.1 18.0 15.5 21.2 26.1 34.1 30.4 21.6 42.1 46.8 23.2 26.1 38.5 44.2 47.8 25.4 62.6 47.4 35.7 34.0 36.6 29.9 60.3 38.3 34.5 27.3 56.1 56.4 29.3 16.4 40.6 39.4 37.3 44.6 37.3 32.8 41.0 40.1 42.4 36.8 36.8 30.9 45.4 9.0 38.5 38.7 40.6 42.7 19.5 48.7 23.7 46.7 39.7 13.6 28.5 19.9 11.4 38.7 68.9 37.5 33.0 73.8 27.9 35.3 32.8 19.4 23.3 21.9 43.7 69.8 38.7 59.6 47.0 10.3 39.5 12.2 47.4 37.7 57.3 34.7 48.9 45.8 47.7 41.1 63.2 53.0 6.7 36.9 40.1 47.0 42.1 41.0 21.0 21.6 20.5 26.3 22.1 20.9 19.5 20.1 20.1 18.7 20.5 21.2 19.1 12.8 14.5 7.8 13.1 13.3 10.4 30.5 18.2 19.0 18.7 21.5 11.7 14.3 16.8 9.2 12.5 28.7 19.2 10.3 54.8 23.1 137.1 14.9 23.6 14.4 16.2 14.1 9.0 19.3 38.5 25.2 10.7 12.8 12.7 20.4 17.2 18.5 24.7 13.5 8.2 12.4 14.2 17.7 17.3 60.3 31.4 19.1 19.6 7.5 24.2 18.3 25.7 3.0 7.6 14.7 10.5 29.3 9.9 11.5 17.6 34.1 15.1 20.4 19.7 16.6 14.5 93.2 14.6 15.0 10.9 11.9 16.2 27.3 18.1 5.7 SNX1 "HsT17379, MGC8664, SNX1A, Vps5" ENSG00000028528 "Sorting nexin 1" Q13596 15 64094123-64146090 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 177.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA047373, HPA052761" Approved Enhanced Endosomes,Lysosomes NA NA 6100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA047373: AB_2680018, HPA052761: AB_2681939" "unprognostic (3.99e-2)" "unprognostic (8.65e-3)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (7.13e-2)" "unprognostic (2.73e-1)" "unprognostic (7.15e-2)" "unprognostic (6.49e-3)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.47e-2)" "unprognostic (3.26e-1)" "prognostic favorable (9.88e-6)" "unprognostic (2.27e-1)" "unprognostic (3.98e-1)" "unprognostic (2.59e-2)" "unprognostic (1.95e-1)" 63.4 69.0 47.1 59.0 64.1 34.8 46.2 60.9 49.8 52.8 44.5 60.2 49.8 47.6 67.7 60.6 37.5 42.9 50.4 46.2 51.4 56.8 69.3 54.7 67.1 67.5 63.6 39.0 44.3 72.1 32.0 57.8 66.4 51.9 47.6 27.0 55.4 64.4 69.1 48.5 52.4 53.0 62.5 61.0 54.8 34.2 57.2 79.5 102.9 36.8 66.8 62.1 51.2 76.8 75.4 93.5 69.1 60.8 116.4 81.3 23.0 93.5 91.5 81.4 94.5 64.6 115.6 74.4 100.5 86.7 79.7 113.8 102.6 95.2 63.5 136.1 56.0 101.2 110.4 98.2 63.6 94.7 108.0 102.9 62.6 65.2 50.2 59.7 86.1 77.0 74.0 29.2 85.1 107.8 111.4 80.2 54.5 103.2 52.1 100.0 65.3 118.1 127.1 170.5 56.3 56.4 91.4 61.1 86.3 59.5 87.0 86.6 103.0 80.1 120.2 50.8 52.5 93.4 220.5 120.1 72.9 123.5 85.8 144.1 149.1 162.1 83.4 143.1 70.9 101.1 70.4 82.2 127.3 101.9 67.0 66.6 113.7 98.1 144.2 86.1 95.8 156.0 47.1 64.1 60.9 49.8 46.2 51.4 67.5 63.6 66.4 62.5 57.2 76.8 34.4 115.4 74.2 35.6 32.9 26.5 38.1 39.3 29.0 18.9 29.7 29.2 50.6 34.3 52.8 18.4 22.9 51.5 51.6 32.1 33.2 40.9 3.7 36.4 36.7 34.2 26.5 26.5 44.2 37.2 35.1 36.2 27.5 44.9 39.2 44.9 35.3 34.2 72.2 15.2 39.3 28.3 28.5 46.8 27.4 4.0 32.3 42.7 32.0 44.0 56.3 19.7 35.0 121.7 177.7 34.6 30.3 37.6 34.0 32.7 39.2 53.6 31.9 16.5 46.0 36.0 64.0 33.3 23.4 33.8 27.1 47.7 35.0 39.3 28.8 33.9 SNX12 ENSG00000147164 "Sorting nexin 12" Q9UMY4 X 71056332-71073426 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB070423 Approved NA NA 89000 "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "CAB070423: AB_11153407" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.39e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (4.83e-3)" "unprognostic (9.88e-3)" "unprognostic (1.61e-2)" "unprognostic (1.34e-1)" "unprognostic (2.46e-1)" "unprognostic (9.55e-2)" "unprognostic (1.29e-3)" "unprognostic (6.15e-2)" "prognostic favorable (1.51e-7)" "unprognostic (3.52e-2)" "unprognostic (8.81e-2)" "unprognostic (1.54e-1)" "unprognostic (9.59e-2)" 26.6 37.6 36.4 27.4 38.3 28.1 29.6 34.4 39.9 31.9 26.0 35.9 37.4 36.1 34.2 49.7 33.2 30.0 40.7 33.7 40.2 42.1 25.0 26.9 23.4 36.8 38.7 39.2 24.8 59.6 18.8 35.6 37.2 33.7 34.3 28.5 27.9 43.9 44.3 43.3 42.8 41.0 37.4 24.1 32.6 16.1 40.6 25.2 42.0 51.3 29.3 40.4 31.2 34.4 67.9 97.6 53.6 46.8 79.9 73.2 58.7 75.8 75.7 74.1 65.7 73.2 110.7 36.4 62.9 89.7 120.3 57.4 104.8 89.4 64.3 29.0 55.4 39.3 108.8 40.7 65.4 38.4 46.0 57.9 94.3 94.5 67.5 61.3 87.1 37.6 60.8 61.3 108.6 69.7 46.5 28.9 71.6 109.7 84.6 45.2 81.6 57.2 60.5 58.3 36.9 28.4 101.4 55.9 65.1 65.2 35.5 30.1 101.5 66.8 64.8 92.6 46.0 35.0 54.8 42.7 64.8 83.9 47.8 6.9 2.9 4.9 2.6 4.2 3.0 4.2 2.9 2.3 3.3 3.1 2.2 3.5 2.5 3.5 2.5 2.7 4.7 1.6 36.4 38.3 34.4 39.9 33.7 40.2 36.8 38.7 37.2 37.4 40.6 34.4 12.2 0.0 6.7 2.9 11.8 15.3 22.5 17.2 22.2 10.1 15.4 13.5 21.4 21.5 12.8 11.0 2.1 40.2 5.6 21.8 11.7 27.3 0.5 3.6 11.8 16.8 10.8 10.1 6.4 24.4 22.5 13.5 10.7 8.2 14.5 6.6 16.8 13.8 24.3 15.2 6.0 16.8 16.2 17.6 11.2 1.2 10.8 12.8 17.8 1.9 24.1 12.5 15.5 7.1 4.8 31.5 9.0 19.9 5.9 12.3 48.1 29.7 3.4 10.2 26.3 8.7 14.8 5.9 14.7 22.2 16.3 33.1 10.1 25.8 16.5 18.0 SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85505496-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Cytosol" "HPA017639: AB_1857345" "unprognostic (1.16e-2)" "unprognostic (3.29e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (1.57e-2)" "unprognostic (3.14e-2)" "unprognostic (2.37e-2)" "unprognostic (1.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (4.72e-3)" 27.3 39.9 39.0 23.0 40.5 31.4 41.7 44.4 61.0 30.8 49.7 39.7 29.8 23.5 57.3 24.3 28.2 28.3 24.8 40.7 47.0 54.4 69.6 39.6 32.6 40.1 40.7 26.8 43.6 47.1 36.3 36.2 43.1 33.2 35.1 47.2 27.8 30.8 16.4 28.6 31.7 22.4 40.9 37.4 45.3 87.0 42.5 18.9 40.5 12.9 28.8 35.1 24.7 44.2 46.1 27.3 44.5 64.9 98.3 71.6 46.0 58.0 78.5 44.2 67.5 49.0 75.4 60.3 69.8 74.4 85.9 60.7 30.5 58.8 69.4 53.3 18.0 66.1 36.4 75.1 80.9 62.4 65.0 63.0 43.7 52.0 51.6 81.1 79.4 23.2 67.7 50.4 96.9 52.1 4.4 117.0 18.3 72.1 31.1 26.2 90.6 29.1 107.1 82.7 19.8 44.5 35.0 76.6 56.3 57.9 47.9 108.9 71.6 35.4 21.8 44.1 60.3 50.4 87.0 22.8 71.3 72.2 71.8 36.7 21.5 33.0 19.9 33.6 14.7 13.3 13.4 18.1 26.2 14.7 12.0 15.0 9.9 22.9 40.9 7.9 16.7 15.7 39.0 40.5 44.4 61.0 40.7 47.0 40.1 40.7 43.1 40.9 42.5 44.2 28.5 93.0 47.2 76.4 25.3 14.7 18.7 32.8 15.9 36.4 23.3 15.1 16.9 15.7 39.1 22.0 56.3 50.4 32.6 30.7 5.9 31.7 87.1 37.3 22.2 26.9 31.8 13.2 115.2 41.6 31.9 23.1 37.8 32.5 31.6 36.0 26.0 28.7 35.4 15.2 124.4 26.1 65.1 37.7 22.3 21.6 19.6 33.4 28.4 63.7 43.1 26.1 41.2 85.5 91.0 34.4 22.0 29.3 23.8 15.7 31.9 25.1 58.9 40.7 19.7 26.2 33.0 173.0 14.9 15.9 14.8 56.5 26.4 26.5 28.6 17.7 SNX2 ENSG00000205302 "Sorting nexin 2" O60749 5 122775079-122834543 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 349.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "memory B-cell: 290.2;naive B-cell: 289.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037400 Approved Supported Endosomes,Lysosomes NA NA 150000 "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Endosomes, Lysosomes" "HPA037400: AB_10670381" "unprognostic (9.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.03e-1)" "unprognostic (3.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "prognostic favorable (8.76e-7)" "unprognostic (8.76e-2)" "unprognostic (1.01e-1)" "unprognostic (1.07e-1)" "unprognostic (8.59e-2)" 40.6 31.0 6.0 17.9 6.5 14.2 33.8 9.5 8.5 27.8 6.2 32.6 13.4 28.2 12.5 30.1 29.0 12.8 22.4 6.2 6.5 37.8 28.0 33.7 26.5 6.4 7.0 37.1 31.3 14.1 23.2 19.2 6.5 24.2 14.5 7.1 29.1 10.1 27.0 29.0 34.8 17.9 6.9 52.4 32.9 17.1 7.1 10.4 38.3 7.7 24.0 33.6 26.1 8.5 18.9 14.1 18.7 13.1 27.8 19.0 79.6 6.2 21.1 15.1 24.2 27.1 27.2 18.8 18.5 14.9 37.4 6.1 24.6 16.2 18.0 13.4 12.2 23.3 15.8 29.7 19.7 7.7 10.8 16.1 12.8 9.6 16.6 17.6 16.8 15.4 10.1 14.9 14.0 16.1 5.5 11.6 6.3 22.2 10.7 20.2 14.3 25.4 17.3 33.9 12.0 13.3 16.0 19.8 17.0 46.4 24.2 16.0 10.7 13.7 6.9 19.1 11.7 4.4 14.9 24.4 13.6 32.1 15.6 77.9 78.5 57.0 15.4 89.1 18.3 290.2 25.7 24.2 66.5 289.1 23.6 21.0 34.7 18.5 86.6 20.1 48.7 72.7 6.0 6.5 9.5 8.5 6.2 6.5 6.4 7.0 6.5 6.9 7.1 8.5 48.4 35.3 42.8 33.0 260.8 40.7 46.9 82.3 45.5 43.1 23.8 29.3 34.4 40.0 62.4 80.9 8.4 153.9 36.2 19.9 131.0 69.1 25.5 71.5 44.7 49.0 31.8 34.3 38.5 51.8 244.9 62.1 52.5 52.2 65.1 41.8 89.6 31.4 349.2 26.9 42.2 32.6 69.2 125.8 75.8 15.0 53.4 133.0 33.8 61.8 215.8 71.7 23.7 51.8 51.4 35.7 37.0 53.0 37.5 28.1 57.8 114.7 77.8 38.0 46.0 42.8 74.5 89.1 75.9 32.9 38.9 122.9 47.2 92.4 39.8 37.5 SNX4 ATG24B ENSG00000114520 "Sorting nexin 4" O95219 3 125446650-125520202 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 163.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005709 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA005709: AB_1080049" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (1.91e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.97e-2)" "unprognostic (1.80e-1)" "unprognostic (1.19e-2)" "unprognostic (6.33e-2)" "unprognostic (4.93e-2)" "unprognostic (4.06e-1)" "unprognostic (3.42e-1)" "unprognostic (6.99e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (7.13e-3)" "unprognostic (1.05e-1)" 16.7 22.1 11.0 12.7 11.2 16.3 25.3 11.5 16.7 19.9 12.4 24.9 35.8 14.1 13.7 14.9 14.2 19.8 16.5 11.1 12.3 53.8 56.5 18.1 16.3 11.9 11.1 14.9 19.5 18.0 14.4 31.7 12.0 22.7 27.7 9.1 22.4 11.4 18.9 10.2 34.2 13.4 11.8 13.0 21.6 16.1 10.8 21.1 44.9 23.3 17.1 16.8 11.3 14.0 34.8 10.9 34.5 21.8 20.9 17.4 39.1 18.5 17.5 35.9 32.1 23.7 15.5 22.0 21.4 22.5 15.5 18.0 32.4 15.6 42.9 20.6 23.8 35.6 14.5 36.0 24.5 37.8 22.1 22.7 17.0 18.2 14.5 20.0 34.1 31.8 38.6 10.9 27.6 26.2 41.8 25.4 20.2 37.6 13.0 38.2 42.0 40.3 33.0 30.6 36.1 50.9 29.8 38.3 47.4 32.0 37.7 61.3 22.3 18.0 22.9 23.4 21.9 22.1 20.1 60.2 22.0 23.8 27.8 12.4 14.0 25.8 9.7 18.8 13.0 13.8 12.4 11.2 18.3 10.3 15.8 13.8 2.6 17.4 19.1 16.1 15.1 12.0 11.0 11.2 11.5 16.7 11.1 12.3 11.9 11.1 12.0 11.8 10.8 14.0 27.1 28.9 39.4 33.6 24.5 12.1 17.9 21.3 12.5 13.4 27.2 17.1 17.7 37.1 34.1 22.0 0.0 87.2 20.6 39.9 60.7 45.4 21.6 23.8 22.1 24.7 30.0 22.7 46.7 36.6 57.8 26.9 26.0 20.9 31.0 30.9 24.7 75.8 50.9 18.5 44.9 37.0 46.8 27.0 22.6 31.5 22.1 28.3 30.2 31.9 45.7 21.3 34.0 37.7 47.8 42.9 37.9 18.0 26.2 22.5 48.8 163.4 37.1 12.0 13.1 27.8 30.3 33.0 29.8 23.0 11.8 41.2 22.9 27.2 29.6 15.7 SNX5 ENSG00000089006 "Sorting nexin 5" Q9Y5X3 20 17941597-17968980 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 271.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 639.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020679, HPA051187, HPA076450" Approved Supported Vesicles,Cytosol NA NA 8200 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020679: , HPA051187: AB_2681379, HPA076450: " "unprognostic (6.00e-2)" "unprognostic (2.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.00e-2)" "unprognostic (4.47e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (2.30e-10)" "unprognostic (1.67e-1)" "unprognostic (6.19e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-2)" "unprognostic (6.50e-2)" "unprognostic (3.48e-2)" "unprognostic (2.99e-1)" 42.4 51.4 12.5 43.7 15.2 57.5 37.6 14.9 12.4 35.7 14.5 37.6 47.1 28.3 49.4 35.2 33.5 24.9 28.5 11.0 13.5 59.3 33.7 36.1 59.1 15.5 13.6 51.4 32.0 24.8 21.7 28.9 16.8 23.6 40.1 14.2 34.3 17.2 70.8 28.7 40.2 24.4 17.2 57.5 33.1 15.5 14.0 21.2 70.2 21.8 51.2 34.7 32.5 21.2 103.0 108.6 45.3 49.6 29.6 49.8 270.7 84.1 43.3 49.9 55.9 104.8 140.2 169.6 48.6 49.9 69.7 112.2 63.8 124.6 67.2 44.1 57.8 150.1 49.5 639.4 48.0 106.6 173.9 49.2 54.2 54.6 98.3 37.1 72.8 111.3 72.8 109.6 58.6 79.6 94.2 92.6 48.4 87.0 55.3 110.0 115.2 126.1 61.2 116.4 45.0 26.4 76.0 113.7 102.1 34.0 62.4 67.8 57.3 77.8 98.7 49.2 101.5 77.8 129.2 137.2 38.5 37.6 69.6 69.6 58.7 83.6 54.8 81.7 50.0 80.6 49.6 54.6 71.9 75.2 29.7 42.7 4.8 39.0 92.3 37.2 67.3 54.9 12.5 15.2 14.9 12.4 11.0 13.5 15.5 13.6 16.8 17.2 14.0 21.2 35.6 64.1 113.1 21.5 93.0 31.7 45.7 49.0 48.3 19.1 48.9 44.2 38.5 38.6 59.8 49.7 27.1 101.0 54.9 59.6 160.4 47.8 43.6 51.1 42.3 48.7 31.7 98.4 18.8 44.8 137.7 57.7 52.0 66.9 130.8 47.9 139.9 41.4 151.9 16.8 19.9 54.4 34.6 174.6 47.2 16.0 60.9 88.2 26.6 31.9 68.4 66.3 55.6 24.6 20.3 37.2 58.3 51.6 96.7 49.2 100.0 271.5 52.0 19.8 19.7 50.7 39.6 19.1 44.6 83.5 32.4 78.5 53.0 66.5 100.1 57.4 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 163.8;liver: 247.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 138.7;Hepatocytes: 649.4;Prostatic glandular cells: 218.8;Proximal tubular cells: 270.2" "Group enriched" "Detected in all" 4 "liver cancer: 30.3;prostate cancer: 72.5;thyroid cancer: 30.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 10 "basophil: 86.3;eosinophil: 55.9" "Lineage enriched" "Detected in all" 12 "granulocytes: 86.3" "Cell line enhanced" "Detected in many" "SK-BR-3: 57.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040260, HPA040621" Enhanced Approved Cytosol NA NA 2800000 "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA040260: AB_10794872, HPA040621: AB_10795384" "unprognostic (8.18e-2)" "unprognostic (7.58e-2)" "unprognostic (8.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.69e-3)" "unprognostic (3.90e-2)" "prognostic favorable (6.14e-5)" "unprognostic (3.33e-3)" "unprognostic (1.67e-1)" "unprognostic (4.95e-2)" "unprognostic (7.04e-3)" "unprognostic (1.40e-1)" "unprognostic (4.26e-2)" "unprognostic (1.23e-2)" "unprognostic (8.53e-2)" "unprognostic (2.31e-2)" "unprognostic (1.56e-1)" 2.0 15.7 4.9 3.1 3.8 2.8 53.8 7.4 8.4 163.8 1.9 5.3 7.5 4.3 6.9 10.2 6.7 8.2 5.6 5.0 4.5 50.3 247.0 3.2 2.6 4.3 3.7 2.4 5.7 4.4 3.1 2.5 4.0 87.9 7.8 4.8 5.3 27.0 2.2 16.6 7.2 3.5 4.2 2.3 9.2 12.2 3.9 3.7 89.4 2.8 3.4 9.1 6.9 6.3 12.3 12.2 4.7 20.8 4.4 5.3 5.9 1.8 3.5 12.2 7.0 12.2 5.8 2.7 8.0 5.4 4.1 17.6 19.9 19.1 9.2 29.9 12.3 13.5 12.1 50.3 0.2 18.0 25.5 6.7 18.0 6.6 9.5 5.4 12.5 15.1 11.7 10.6 14.9 8.1 18.4 38.3 39.0 29.4 13.8 0.9 16.6 6.4 16.8 12.1 25.1 12.2 2.1 57.3 5.9 5.2 16.4 22.5 4.7 3.5 38.0 1.6 5.8 8.7 4.5 4.4 14.2 18.6 10.6 86.3 1.7 55.9 1.6 1.5 1.7 5.4 1.3 1.6 1.7 6.9 1.6 1.4 3.8 1.1 2.1 2.4 2.5 2.0 4.9 3.8 7.4 8.4 5.0 4.5 4.3 3.7 4.0 4.2 3.9 6.3 3.9 0.0 3.1 5.5 11.9 7.8 26.5 14.8 17.6 10.8 24.7 17.5 3.2 25.8 28.1 33.1 0.0 1.3 2.3 15.0 29.4 68.2 31.7 40.2 17.4 4.9 84.8 37.5 4.8 138.7 5.1 7.5 31.1 43.7 8.8 11.5 15.7 649.4 16.0 3.3 5.4 32.5 22.4 24.2 6.4 24.1 3.7 12.2 16.0 1.0 13.3 9.0 2.1 7.1 8.9 89.0 18.1 6.0 7.9 218.8 8.0 270.2 42.5 4.7 0.0 8.9 8.9 7.4 2.8 35.1 20.3 1.0 6.5 15.3 39.4 131.2 SOWAHB ANKRD56 ENSG00000186212 "Sosondowah ankyrin repeat domain family member B" A6NEL2 4 76894152-76898144 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.1" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Gastric mucus-secreting cells: 4.6;Squamous epithelial cells: 2.7;Urothelial cells: 6.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.9;BEWO: 8.3;CACO-2: 3.9;OE19: 7.4;RT4: 19.4;T-47d: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA036809, HPA036810" Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli fibrillar center" "HPA036809: AB_10672479, HPA036810: AB_2675327" "unprognostic (2.05e-1)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-2)" "unprognostic (1.02e-2)" "unprognostic (3.28e-2)" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (3.06e-1)" "unprognostic (2.85e-2)" "unprognostic (1.46e-1)" "prognostic favorable (1.22e-15)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (3.73e-3)" 0.0 0.3 1.2 0.7 1.4 0.0 1.3 0.0 2.8 1.0 0.7 7.7 5.5 0.3 0.8 6.2 1.1 1.3 0.0 1.8 0.1 7.7 19.1 1.6 0.0 0.5 0.0 0.0 5.8 6.9 0.4 0.6 0.6 0.8 6.3 0.2 2.4 2.7 0.0 1.5 8.1 0.2 0.0 0.0 4.6 0.0 0.0 0.2 2.4 0.0 2.3 6.0 2.2 1.1 3.9 0.1 0.3 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 3.9 2.6 0.0 0.1 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 7.4 0.0 0.0 0.0 0.0 0.5 19.4 0.1 0.0 0.0 1.7 0.0 0.6 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.0 2.8 1.8 0.1 0.5 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.2 0.0 0.8 0.0 0.2 0.0 0.0 0.2 0.0 1.5 1.9 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 4.6 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.1 1.1 0.9 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.5 6.1 SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.7;salivary gland: 80.1" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Basal squamous epithelial cells: 166.8;Breast glandular cells: 141.0;Cholangiocytes: 190.1;Gastric mucus-secreting cells: 144.8;Muller glia cells: 141.3;Squamous epithelial cells: 273.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 78.1;Hep G2: 97.0;OE19: 74.3;U-251 MG: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001758, CAB022456, CAB068240" Enhanced Enhanced Nucleoplasm NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB022456: , CAB068240: AB_2665670, HPA001758: AB_1080067" "unprognostic (6.92e-2)" "unprognostic (1.73e-2)" "unprognostic (4.47e-3)" "unprognostic (4.43e-2)" "unprognostic (2.55e-2)" "unprognostic (7.96e-3)" "unprognostic (4.32e-3)" "prognostic unfavorable (2.07e-4)" "unprognostic (4.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.92e-3)" "unprognostic (1.21e-1)" "unprognostic (3.26e-3)" "unprognostic (2.77e-3)" "unprognostic (1.15e-1)" "unprognostic (8.88e-2)" "unprognostic (1.21e-2)" 3.1 2.2 54.7 4.4 50.4 0.1 28.0 42.3 58.5 7.4 46.8 17.1 19.7 2.9 0.9 13.7 7.5 13.0 15.8 50.6 49.3 12.7 3.5 3.1 1.1 73.7 72.2 0.3 38.4 0.1 10.3 0.3 48.8 24.8 17.8 15.0 80.1 10.9 2.7 23.3 15.1 1.2 56.9 0.2 40.5 30.7 51.4 0.5 20.2 1.2 4.4 1.9 6.4 49.0 31.1 19.2 38.9 78.1 3.9 1.1 0.1 4.8 4.2 8.2 4.4 27.0 40.8 0.0 2.9 1.1 43.8 31.3 0.0 18.6 7.5 0.0 2.5 0.0 4.2 97.0 0.3 0.0 0.1 0.7 1.6 9.5 9.0 47.0 0.0 0.0 0.0 0.1 11.7 0.4 0.0 0.1 1.5 74.3 29.1 0.0 31.4 0.4 35.2 2.0 1.9 1.9 4.0 4.7 0.1 21.0 16.7 0.2 0.0 15.8 42.0 8.5 66.5 0.0 0.0 0.1 11.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.4 42.3 58.5 50.6 49.3 73.7 72.2 48.8 56.9 51.4 49.0 1.1 12.8 5.6 160.0 1.9 55.4 88.2 28.9 166.8 3.0 141.0 108.2 13.6 190.1 21.1 36.8 0.0 0.3 2.8 52.1 7.9 55.3 5.1 18.4 0.9 3.2 59.7 0.0 3.1 46.7 0.0 26.0 144.8 21.7 4.5 1.9 0.0 3.4 0.2 0.0 1.5 99.0 24.4 0.0 3.4 14.5 4.4 2.3 12.4 9.4 1.0 141.3 0.0 4.5 11.1 40.8 39.1 0.4 2.8 81.1 17.7 61.0 36.4 6.8 6.6 59.9 14.5 10.2 3.1 273.5 17.8 0.1 2.8 0.1 103.8 77.2 SPA17 "CT22, SP17" ENSG00000064199 "Sperm autoantigenic protein 17" Q15506 11 124673844-124697518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 231.3" "Cell type enhanced" "Detected in many" "Early spermatids: 1583.7;Endometrial ciliated cells: 371.2;Late spermatids: 2667.9;Respiratory ciliated cells: 368.6;Spermatocytes: 580.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037568 Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA037568: AB_10672905" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (2.39e-3)" "prognostic favorable (1.03e-4)" "unprognostic (2.85e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-4)" "unprognostic (2.64e-1)" "unprognostic (3.80e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (8.54e-2)" "unprognostic (1.71e-3)" "unprognostic (6.78e-2)" "unprognostic (9.78e-3)" "unprognostic (8.52e-2)" "unprognostic (2.71e-1)" 3.2 4.2 2.6 1.1 2.8 1.6 3.8 2.4 2.6 4.4 9.0 5.4 1.4 4.4 10.5 5.0 24.5 2.3 4.5 2.8 3.1 11.6 2.1 7.7 1.0 4.6 4.9 1.6 4.3 4.7 13.5 0.9 4.1 4.3 3.2 1.0 3.5 2.1 1.2 2.6 3.0 1.6 3.8 1.8 4.0 231.3 3.3 2.6 8.9 0.2 1.4 3.2 3.0 3.3 4.1 5.4 12.6 4.3 4.2 6.4 4.7 3.8 8.4 5.4 4.4 1.4 11.5 2.8 2.2 6.7 4.3 3.4 4.9 8.0 7.3 2.6 3.6 3.6 0.8 2.4 2.3 1.0 1.6 2.6 4.8 7.9 4.1 4.2 4.5 5.7 5.5 2.2 12.4 5.5 0.5 0.2 4.7 8.3 4.3 3.8 1.5 0.1 12.8 3.1 6.6 5.8 9.1 2.7 1.8 4.6 17.1 3.1 3.2 4.8 3.8 2.8 4.5 1.4 0.9 1.1 5.0 0.9 5.1 0.5 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.1 0.0 0.2 2.6 2.8 2.4 2.6 2.8 3.1 4.6 4.9 4.1 3.8 3.3 3.3 5.9 3.2 12.6 3.6 0.9 2.7 4.7 26.9 1.8 2.6 6.2 6.5 2.1 17.2 54.2 20.2 4.2 6.7 2.3 13.0 19.6 29.2 1583.7 371.2 13.8 7.2 7.2 3.2 5.8 15.5 10.8 5.8 8.2 19.4 0.0 7.1 1.8 1.5 11.9 0.0 2.8 9.2 32.6 3.1 1.0 2667.9 28.0 6.6 1.8 1.9 2.6 8.1 0.0 1.0 0.7 12.7 10.0 18.0 1.4 2.9 6.3 47.0 368.6 1.2 13.1 6.2 10.5 580.0 63.6 4.9 2.3 2.7 2.6 8.4 10.4 5.6 SPATA2 "KIAA0757, PD1, PPP1R145, tamo" ENSG00000158480 "Spermatogenesis associated 2" Q9UM82 20 49903391-49915529 "Predicted intracellular proteins" Necrosis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 45.2;Late spermatids: 62.5;Spermatocytes: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048581, HPA052224" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA048581: AB_2680449, HPA052224: AB_2681769" "unprognostic (4.02e-2)" "unprognostic (5.98e-2)" "unprognostic (8.26e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.76e-1)" "unprognostic (2.90e-2)" "unprognostic (3.25e-3)" "unprognostic (8.77e-2)" "prognostic favorable (9.08e-4)" "unprognostic (8.33e-2)" "unprognostic (6.45e-3)" "unprognostic (5.99e-2)" "unprognostic (4.89e-2)" "unprognostic (9.57e-2)" "unprognostic (4.38e-1)" "prognostic unfavorable (4.53e-4)" "unprognostic (2.52e-1)" 3.9 5.8 19.9 3.7 21.6 12.2 3.7 17.5 20.9 3.9 8.1 7.8 7.8 5.3 3.6 5.6 4.7 3.4 6.9 21.0 16.7 5.0 5.8 4.0 3.6 17.2 19.0 4.5 8.0 5.6 7.9 3.5 16.7 5.8 6.3 6.5 5.9 3.9 13.1 5.0 7.5 3.1 17.0 11.4 5.7 14.3 21.1 3.8 8.0 7.8 3.6 4.1 3.7 21.5 7.8 9.4 6.3 5.7 7.0 5.0 10.3 4.9 7.2 16.7 7.0 29.7 6.1 5.9 10.1 4.9 8.6 14.1 4.7 8.1 8.8 8.3 4.5 3.1 5.6 19.5 6.6 8.5 12.2 5.0 9.6 8.6 5.4 5.5 3.6 8.2 10.8 6.6 4.0 16.5 8.7 21.5 9.5 10.5 11.3 6.5 6.8 6.2 5.4 6.1 6.0 6.4 9.8 29.6 7.8 4.9 7.2 7.3 5.1 11.9 9.8 9.9 7.0 16.2 13.4 6.3 9.3 4.4 5.4 0.1 1.5 1.4 1.4 1.1 1.3 1.3 1.3 1.7 1.3 2.1 1.6 1.9 2.5 1.5 0.5 0.6 1.5 1.0 19.9 21.6 17.5 20.9 21.0 16.7 17.2 19.0 16.7 17.0 21.1 21.5 5.4 9.6 2.2 2.9 7.8 7.4 6.6 4.3 12.5 7.4 11.9 8.6 4.9 10.0 2.8 0.0 8.4 11.0 8.3 34.7 3.9 6.0 45.2 11.4 4.7 6.3 26.4 1.7 6.8 8.0 13.4 5.4 9.7 9.0 4.5 5.4 10.4 7.1 4.8 6.7 5.0 22.2 2.0 4.4 5.4 62.5 5.0 3.6 5.4 1.9 7.0 5.4 4.1 2.0 8.5 8.3 16.1 5.7 6.4 7.4 20.7 4.8 6.7 7.6 6.6 5.8 6.6 41.3 16.9 7.8 7.2 30.1 6.8 10.3 18.4 8.5 SPATA24 "CCDC161, T6441" ENSG00000170469 "Spermatogenesis associated 24" Q86W54 5 139396563-139404089 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "testis: 147.0" "Group enriched" "Detected in many" 26 "Early spermatids: 1073.6;Late spermatids: 2829.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 85.6" HPA044000 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA044000: AB_10959668" "unprognostic (2.19e-3)" "unprognostic (1.18e-1)" "unprognostic (2.09e-1)" "unprognostic (9.30e-2)" "unprognostic (3.82e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.26e-2)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (5.36e-3)" "unprognostic (1.07e-1)" "unprognostic (6.11e-2)" "unprognostic (1.24e-1)" "unprognostic (3.44e-1)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" 2.9 7.1 6.1 2.9 5.4 1.8 4.1 5.5 7.1 3.3 5.8 4.6 6.5 4.1 21.0 3.4 15.0 3.8 20.6 5.9 6.6 15.0 5.1 3.1 7.2 7.8 8.0 4.2 5.3 12.5 12.7 3.1 7.0 4.9 2.9 6.5 6.6 4.0 23.0 2.9 7.1 2.9 7.6 4.0 4.3 147.0 6.2 3.1 7.3 19.2 5.4 3.9 3.2 6.1 13.4 8.4 11.6 6.3 3.3 6.5 9.2 3.3 6.3 7.0 12.0 18.7 17.2 21.0 9.5 6.4 23.5 7.3 8.7 14.6 7.4 85.6 10.4 6.5 15.7 14.4 12.7 1.4 11.1 5.7 7.1 10.2 12.6 7.7 8.3 13.3 6.5 36.1 9.3 7.4 13.8 10.1 8.5 5.4 7.1 31.6 7.5 28.9 16.3 7.2 8.8 8.0 12.8 24.2 6.0 28.0 7.0 14.5 15.3 4.1 5.3 7.7 9.5 8.7 8.9 19.4 7.6 10.8 3.4 0.0 2.1 1.5 3.0 1.6 4.1 3.5 3.1 3.5 2.4 1.9 3.4 4.8 0.1 2.0 0.6 1.4 1.5 1.5 6.1 5.4 5.5 7.1 5.9 6.6 7.8 8.0 7.0 7.6 6.2 6.1 2.2 0.0 4.1 2.6 3.4 1.7 6.4 6.4 2.8 0.3 3.8 3.4 24.7 7.2 3.7 5.5 8.4 6.0 2.3 3.0 13.7 4.6 1073.6 14.9 1.6 4.1 0.0 0.8 1.0 1.8 3.2 2.2 2.0 2.4 0.0 3.6 4.2 3.7 5.2 1.7 1.3 1.5 2.0 2.7 1.4 2829.6 14.3 2.4 1.8 0.0 1.5 3.3 7.2 0.5 0.9 2.6 3.1 13.5 1.7 3.3 6.8 36.5 20.8 1.4 26.3 3.7 4.1 75.0 18.2 2.4 1.8 4.5 3.2 8.5 3.1 5.4 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 95.3 154.7 75.1 64.1 76.6 61.3 100.5 80.7 101.1 97.4 88.7 110.1 94.8 101.0 110.8 117.0 92.1 48.4 119.7 75.4 83.9 137.3 172.8 87.8 71.2 82.3 80.5 91.1 231.2 89.5 141.1 59.4 82.1 96.3 84.7 124.6 145.2 79.1 142.2 109.0 103.9 53.0 81.7 105.6 151.1 153.2 81.4 66.6 113.2 49.7 87.1 103.0 94.7 84.9 114.6 102.2 113.4 139.3 164.9 134.4 157.2 157.6 144.5 139.4 128.4 108.1 171.0 114.6 65.7 145.4 142.5 110.2 109.9 142.5 149.1 154.3 115.8 138.6 169.2 164.6 175.1 213.3 229.1 104.7 190.5 148.5 174.4 130.5 117.4 147.5 118.8 418.0 151.8 105.5 168.8 207.2 195.8 317.2 203.9 67.9 95.7 608.6 232.7 148.3 73.6 157.4 148.7 178.1 224.2 102.4 188.1 248.1 106.2 127.3 119.1 226.3 192.1 406.2 654.1 169.8 196.5 209.4 169.8 292.7 129.9 258.2 131.1 137.0 155.1 202.0 158.5 144.2 143.9 149.3 146.8 152.1 100.1 119.6 152.5 620.5 177.1 253.8 75.1 76.6 80.7 101.1 75.4 83.9 82.3 80.5 82.1 81.7 81.4 84.9 172.5 64.1 104.2 23.8 282.3 156.5 227.9 470.7 136.1 465.4 289.0 351.0 148.7 221.6 283.6 310.8 118.9 373.5 488.1 195.2 361.9 353.8 597.8 286.4 180.8 157.6 167.7 143.9 27.1 339.4 399.8 181.9 119.8 181.5 211.6 138.7 131.4 301.8 311.0 102.6 34.4 291.3 325.5 202.9 189.9 1177.6 216.3 192.5 380.6 13.1 321.9 296.9 213.1 21.1 53.2 274.8 274.1 191.8 888.8 295.0 405.5 665.1 374.1 251.3 164.3 152.6 335.5 746.4 504.5 195.8 184.4 351.2 220.8 283.6 267.7 285.3 SPCS2 KIAA0102 ENSG00000118363 "Signal peptidase complex subunit 2" Q15005 11 74949247-74979033 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 933.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013386 Approved Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA013386: AB_1857426" "unprognostic (2.43e-1)" "unprognostic (7.01e-2)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (9.30e-2)" "unprognostic (2.31e-2)" "unprognostic (7.04e-3)" "unprognostic (9.61e-2)" "unprognostic (8.83e-2)" "unprognostic (2.02e-3)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (5.70e-2)" "unprognostic (1.37e-1)" "unprognostic (8.62e-2)" 81.0 99.4 86.4 104.9 96.6 60.1 108.2 98.7 131.1 127.5 88.8 119.3 90.5 92.2 220.1 72.8 95.9 66.5 76.2 86.3 102.7 105.6 151.6 79.5 98.2 98.5 93.3 84.3 137.3 147.7 75.1 81.2 98.9 106.9 115.1 75.4 139.0 93.3 71.4 56.6 83.3 93.1 99.7 92.5 105.5 50.4 94.3 97.8 143.9 69.5 154.8 95.0 68.1 107.7 141.7 163.4 213.2 192.2 183.2 122.0 115.9 198.6 192.4 179.0 154.8 322.9 311.7 228.2 244.1 168.9 213.6 254.2 187.3 146.1 220.5 190.0 136.4 232.2 189.7 268.9 208.1 249.3 156.7 109.7 186.1 151.5 245.5 156.8 173.7 166.6 271.9 578.0 163.9 215.0 179.1 158.0 131.0 558.3 153.5 219.2 328.2 522.4 208.2 232.3 172.3 172.6 198.1 262.9 687.6 146.7 254.1 187.6 142.0 201.9 124.9 212.1 177.5 245.1 268.8 423.8 83.0 173.4 209.4 546.3 229.2 219.2 279.8 231.0 315.2 400.7 253.7 269.4 222.0 344.3 191.7 229.5 148.5 260.9 209.8 459.5 272.0 428.3 86.4 96.6 98.7 131.1 86.3 102.7 98.5 93.3 98.9 99.7 94.3 107.7 192.3 86.6 143.6 40.5 323.2 304.5 314.0 812.0 129.7 97.6 212.6 199.9 69.1 214.4 406.0 239.1 52.1 330.8 233.5 130.3 189.8 290.0 36.5 126.4 250.4 181.4 125.4 191.5 46.6 288.0 334.4 239.4 104.5 240.2 155.2 114.7 158.1 338.0 278.9 95.9 55.4 255.1 431.3 140.1 283.3 27.2 240.8 159.7 521.2 23.4 188.6 215.6 197.8 48.7 73.5 253.2 140.0 195.6 933.5 355.5 141.7 280.8 231.1 87.3 170.9 153.6 253.6 127.8 133.1 112.1 229.4 464.8 204.6 192.2 189.5 298.1 SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Cardiomyocytes: 61.5;Late spermatids: 39.6;Sertoli cells: 46.0;Smooth muscle cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 45.9;U-87 MG: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 16.1 6.8 16.8 7.7 18.7 0.0 15.3 15.5 20.7 75.5 9.7 174.8 5.3 89.5 6.2 15.6 70.0 7.3 48.5 19.8 14.5 4.1 1.3 8.7 0.6 16.1 15.8 21.9 3.4 4.4 34.3 4.5 14.6 58.8 3.8 1.0 10.0 25.5 118.0 7.8 31.9 23.1 15.3 2.4 48.1 5.4 15.3 0.5 5.9 21.7 0.2 87.7 42.1 15.6 6.1 0.5 3.1 4.9 1.6 4.7 1.8 13.1 8.5 8.6 6.4 4.5 1.9 0.0 4.5 9.7 4.3 7.2 2.5 3.1 3.4 0.0 1.7 0.0 6.1 0.3 2.1 0.0 0.5 13.2 4.6 7.8 1.9 45.9 0.0 3.2 3.5 0.0 6.1 1.6 0.1 18.8 6.5 0.0 2.4 2.8 7.0 1.1 8.5 0.0 3.4 15.1 0.6 0.0 0.3 14.3 0.3 0.2 0.0 20.6 21.3 2.4 21.1 0.4 0.0 0.2 23.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 18.7 15.5 20.7 19.8 14.5 16.1 15.8 14.6 15.3 15.3 15.6 2.4 0.0 2.2 45.7 0.4 3.2 6.0 1.3 2.8 5.3 10.3 14.6 61.5 4.3 0.1 1.8 2.1 0.6 1.4 4.1 0.0 1.5 21.8 0.9 3.6 2.2 6.7 2.7 20.5 1.2 0.9 10.0 3.6 1.3 0.0 1.0 5.7 3.1 1.1 5.0 20.9 4.1 0.0 5.6 1.9 39.6 10.5 1.6 3.6 4.7 1.4 8.4 0.0 5.0 1.0 0.2 3.2 18.8 0.9 6.5 8.5 4.3 0.1 0.9 46.0 17.1 32.4 11.6 3.7 0.2 1.4 1.4 1.2 0.4 3.5 5.3 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" 56.6 61.7 48.4 50.8 54.1 69.4 68.8 51.5 52.9 60.4 66.0 61.6 52.1 60.2 150.1 46.1 73.4 54.7 54.4 47.8 50.3 85.3 113.1 61.9 56.9 52.1 50.2 55.3 54.7 72.1 47.1 66.3 52.7 49.8 59.3 38.6 45.7 59.0 74.3 58.5 46.6 64.5 51.1 52.6 60.1 35.0 52.6 57.7 83.1 42.4 58.8 61.2 47.8 59.4 87.0 127.0 62.8 119.5 158.7 155.7 78.0 52.8 179.7 103.2 119.8 57.4 131.1 99.1 80.6 124.8 153.1 113.3 182.1 124.5 97.8 41.0 58.5 85.7 81.7 104.0 200.7 82.2 72.7 107.0 139.3 82.1 154.2 100.7 125.6 112.2 72.7 78.3 127.8 124.1 75.8 71.5 69.6 193.9 66.3 78.2 67.3 174.6 107.1 103.6 76.7 68.6 62.7 131.4 124.9 123.3 89.9 140.9 61.5 87.1 90.6 125.4 80.6 55.6 101.8 58.2 112.8 215.1 75.1 9.9 138.2 15.5 14.1 84.2 13.1 39.0 13.8 14.7 76.9 37.6 19.9 10.9 181.4 15.7 69.8 25.1 17.5 52.3 48.4 54.1 51.5 52.9 47.8 50.3 52.1 50.2 52.7 51.1 52.6 59.4 29.4 9.6 56.3 11.1 67.7 74.9 81.8 70.6 66.6 16.2 62.7 39.4 32.1 61.5 51.5 71.7 37.5 202.9 33.6 42.7 137.0 97.1 6.0 32.9 36.9 56.9 64.8 54.3 13.1 74.1 92.2 67.5 46.9 34.3 28.5 37.5 38.2 121.6 153.9 20.2 13.7 58.2 61.1 158.7 145.4 13.2 86.6 128.5 80.0 16.9 123.2 24.8 64.9 5.5 19.6 62.3 93.5 89.9 66.2 145.2 121.1 202.3 57.9 18.9 39.5 93.4 39.5 35.4 51.3 75.4 82.8 186.5 46.5 35.5 69.5 123.5 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SRBD1 FLJ10379 ENSG00000068784 "S1 RNA binding domain 1" Q8N5C6 2 45388680-45612165 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030567, HPA030568" Approved Approved Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" "HPA030567: AB_10611244, HPA030568: AB_10601856" "unprognostic (1.16e-2)" "unprognostic (1.27e-1)" "unprognostic (4.97e-3)" "unprognostic (2.46e-1)" "unprognostic (8.20e-3)" "unprognostic (4.14e-1)" "unprognostic (8.69e-3)" "unprognostic (9.74e-2)" "unprognostic (7.11e-2)" "unprognostic (9.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.76e-1)" "unprognostic (3.42e-3)" "unprognostic (3.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (2.29e-1)" 6.8 5.6 1.9 7.2 2.5 6.5 7.6 2.1 1.9 9.8 3.5 7.1 5.7 7.2 11.8 4.7 5.4 5.6 5.8 1.7 2.5 7.6 8.7 6.5 7.5 2.5 2.3 5.4 7.3 12.2 3.7 6.8 2.8 7.4 8.0 3.7 5.2 5.7 3.1 3.8 5.4 6.8 2.4 8.6 8.1 9.0 2.5 11.5 10.2 4.9 7.5 5.3 3.9 2.8 18.7 9.5 19.1 12.9 6.9 15.0 15.1 14.1 12.2 13.2 12.1 8.0 7.8 16.1 10.2 10.1 9.8 8.7 19.0 17.9 24.3 22.1 10.6 21.4 7.4 17.3 8.1 17.9 12.1 9.3 7.2 15.7 18.2 5.8 16.2 5.8 15.6 11.9 19.8 17.0 24.3 13.8 21.9 12.0 10.3 16.5 27.5 14.7 15.0 12.1 16.8 13.7 12.3 13.1 14.0 9.9 8.2 6.4 14.9 18.4 14.7 9.0 12.3 12.5 4.9 9.6 10.4 17.6 13.5 3.9 6.2 13.1 5.4 7.0 4.8 5.3 4.0 6.3 6.1 4.6 5.4 5.0 2.3 8.3 12.3 5.7 4.5 4.3 1.9 2.5 2.1 1.9 1.7 2.5 2.5 2.3 2.8 2.4 2.5 2.8 10.9 19.2 7.7 28.7 13.0 3.6 3.5 6.2 8.6 7.9 8.7 8.0 8.8 8.6 10.6 3.7 4.2 8.4 15.7 5.9 9.8 8.3 3.5 11.5 20.7 9.3 7.2 15.8 22.0 9.1 7.1 10.9 20.9 9.9 8.2 11.0 7.9 13.8 9.6 13.5 32.7 9.7 0.0 22.5 3.9 2.5 7.5 13.8 7.2 46.9 13.7 12.9 13.4 48.2 51.8 4.6 6.3 6.4 19.8 2.9 5.9 10.8 7.8 14.7 13.1 12.9 10.2 37.5 28.4 9.5 3.8 5.6 12.8 16.6 5.1 2.2 SRP14 "ALURBP, MGC14326" ENSG00000140319 "Signal recognition particle 14" P37108 15 40035690-40039181 "Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053738, HPA065118" Approved Nucleoplasm,Nucleoli NA NA 440000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA053738: , HPA065118: " "unprognostic (2.52e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-3)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (5.39e-3)" "unprognostic (2.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (7.99e-2)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.31e-4)" "unprognostic (2.20e-1)" "unprognostic (8.03e-3)" "unprognostic (1.41e-3)" "unprognostic (4.94e-2)" 309.1 307.5 330.1 118.1 327.1 252.7 300.4 323.8 426.0 301.7 320.4 272.5 121.5 311.2 282.1 257.7 270.7 155.8 390.1 317.9 349.3 391.5 229.5 220.8 168.0 357.0 402.7 323.5 192.4 324.3 306.8 143.8 339.7 264.4 158.9 212.8 237.8 158.9 354.7 201.2 215.7 163.4 321.1 219.7 247.6 165.6 326.2 276.9 275.6 338.5 172.9 266.7 253.9 355.1 131.8 163.7 399.5 301.4 300.0 275.5 189.4 232.4 265.0 213.4 223.3 297.8 113.7 107.9 245.0 305.1 319.5 216.6 322.8 260.9 207.0 257.5 230.3 258.3 530.2 364.0 231.4 238.2 211.8 276.0 298.3 177.8 213.3 391.0 360.6 297.7 280.2 204.2 356.3 204.5 370.2 291.4 217.6 520.1 301.3 247.6 176.8 192.6 477.5 401.7 287.2 255.0 231.2 243.2 171.2 243.7 332.8 448.6 290.9 240.4 160.3 229.4 171.1 161.8 494.7 291.0 234.7 255.4 229.7 729.8 525.0 875.7 484.5 485.8 473.9 600.9 547.9 549.0 562.5 509.0 522.0 510.2 452.7 525.9 459.5 1148.0 755.1 1262.6 330.1 327.1 323.8 426.0 317.9 349.3 357.0 402.7 339.7 321.1 326.2 355.1 1378.8 461.6 415.0 83.2 577.0 667.1 861.7 1395.7 427.4 432.9 617.7 914.5 880.3 649.1 906.9 995.0 125.1 867.3 812.5 742.7 2551.3 1366.9 353.1 1215.7 729.8 957.7 554.0 619.4 39.4 1087.2 1100.4 699.1 324.7 1513.6 564.0 669.5 654.7 819.4 1022.1 348.3 56.1 676.9 1226.8 631.1 882.8 377.3 1039.8 645.8 789.8 36.5 1174.3 1262.8 619.0 39.2 76.0 1240.7 894.4 986.9 610.9 826.3 874.5 2276.2 935.5 477.3 624.5 651.9 749.3 779.9 643.1 631.5 710.3 758.8 644.1 831.9 673.2 975.0 SRP9 ENSG00000143742 "Signal recognition particle 9" P49458 1 225777813-225790468 "Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 22000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.45e-2)" "unprognostic (2.28e-1)" "unprognostic (5.84e-2)" "unprognostic (9.00e-2)" "unprognostic (1.59e-1)" "unprognostic (2.75e-2)" "unprognostic (3.40e-2)" "unprognostic (2.02e-1)" "unprognostic (3.78e-2)" "unprognostic (1.57e-3)" "unprognostic (1.30e-1)" "unprognostic (1.83e-1)" "unprognostic (5.06e-2)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" 153.1 254.2 200.6 140.1 202.9 182.6 228.7 211.2 279.3 162.7 207.6 207.3 165.5 151.8 215.3 148.4 163.1 161.3 197.9 195.7 232.4 266.6 350.5 136.6 194.1 202.8 204.5 155.6 135.5 218.0 113.0 116.3 213.4 189.6 202.5 165.1 156.1 139.5 255.3 129.0 164.1 148.9 219.2 135.2 148.7 113.4 211.8 270.4 193.0 265.4 197.6 167.0 93.1 225.4 453.4 259.9 712.4 371.3 288.7 352.2 274.8 310.0 335.2 336.3 390.3 291.0 323.9 450.0 410.8 376.9 319.4 284.5 450.8 375.1 489.7 375.6 613.9 363.8 347.7 398.5 245.5 667.8 302.7 260.9 341.2 308.3 382.0 360.3 534.8 450.5 657.0 299.2 562.2 199.7 629.2 484.1 227.9 816.3 436.9 496.5 664.4 523.7 540.7 424.8 624.2 532.6 356.7 407.9 461.6 363.4 471.1 619.7 342.4 299.8 263.1 404.4 589.9 174.0 537.1 420.0 347.5 450.9 597.1 343.8 316.8 376.9 270.1 350.2 343.7 340.9 333.0 312.7 354.4 296.4 395.5 340.2 177.3 371.2 305.2 256.8 457.0 635.4 200.6 202.9 211.2 279.3 195.7 232.4 202.8 204.5 213.4 219.2 211.8 225.4 217.7 105.8 96.0 30.7 162.9 262.8 185.6 410.5 126.3 67.5 234.4 181.0 157.6 205.9 224.8 174.7 31.3 221.7 145.4 151.0 598.7 256.4 39.1 228.8 121.3 174.3 239.9 223.2 21.3 186.2 259.0 171.4 135.1 158.9 84.3 204.3 127.5 201.2 207.5 63.9 29.3 244.8 518.8 129.4 213.9 34.9 187.4 128.0 316.6 15.9 177.2 556.2 201.8 25.6 40.4 179.2 172.0 212.5 154.7 249.8 152.7 537.3 236.7 101.1 131.5 114.1 208.0 302.6 123.1 190.2 290.2 199.1 167.8 322.8 248.0 264.2 SRRD "HC/HCC, SRR1L" ENSG00000100104 "SRR1 domain containing" Q9UH36 22 26483877-26494658 "Predicted intracellular proteins" "Biological rhythms, Heme biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 49.0;Late spermatids: 54.9;Pancreatic endocrine cells: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002945 Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA002945: AB_1079265" "unprognostic (3.25e-1)" "unprognostic (3.01e-2)" "unprognostic (1.65e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (9.00e-2)" "unprognostic (8.51e-3)" "unprognostic (2.49e-2)" "unprognostic (4.50e-3)" "unprognostic (3.93e-2)" "unprognostic (2.63e-1)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (1.76e-3)" "unprognostic (2.96e-1)" 5.0 3.5 8.4 4.1 8.8 6.2 6.2 10.4 9.7 5.5 6.2 6.0 3.6 6.3 6.1 5.3 5.5 3.7 7.6 8.7 8.0 6.4 6.9 5.3 5.6 8.2 8.2 7.1 5.5 6.7 5.1 5.3 7.7 6.8 5.2 5.8 4.9 7.2 19.6 6.0 3.9 7.0 8.1 5.4 4.9 4.8 8.6 5.7 10.5 17.1 7.3 5.5 4.2 8.6 10.7 6.3 10.6 10.9 10.8 6.5 6.1 7.4 10.4 14.7 13.5 6.2 4.6 23.6 5.1 9.7 7.4 9.5 16.6 15.6 14.3 12.2 16.5 10.4 5.5 10.1 7.6 23.1 7.8 6.2 13.4 10.5 16.4 9.7 12.9 13.8 17.2 14.5 9.7 9.2 10.4 7.3 6.6 11.7 7.9 23.3 13.2 17.0 9.7 7.6 11.2 7.6 8.5 7.6 19.7 8.8 9.1 9.0 9.9 11.3 37.2 6.4 13.1 9.5 8.3 19.4 7.7 9.4 15.0 0.3 0.5 0.2 0.7 0.4 1.0 1.1 0.8 1.0 0.5 0.6 1.1 1.2 0.4 0.9 0.4 0.4 0.2 0.3 8.4 8.8 10.4 9.7 8.7 8.0 8.2 8.2 7.7 8.1 8.6 8.6 12.1 0.0 6.4 3.6 10.6 29.7 16.2 7.5 3.4 13.0 10.0 10.5 3.0 12.8 5.9 1.8 2.1 13.3 5.9 3.7 9.8 24.9 22.4 5.8 10.6 11.2 4.8 46.9 3.1 49.0 22.9 8.9 7.7 8.9 11.4 15.1 11.0 15.4 14.1 13.5 3.0 4.5 2.0 3.8 8.6 54.9 7.2 8.6 8.8 1.0 6.1 9.8 10.3 3.5 1.9 48.9 2.4 9.1 10.4 12.1 3.4 19.9 3.2 9.3 6.6 12.6 10.3 17.8 12.9 7.7 31.8 16.7 9.1 21.7 5.9 14.7 SRSF9 "SFRS9, SRp30c" ENSG00000111786 "Serine and arginine rich splicing factor 9" Q13242 12 120461672-120469748 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049849 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Nucleoli "HPA049849: AB_2680911" "unprognostic (3.80e-1)" "unprognostic (3.84e-1)" "unprognostic (1.50e-1)" "unprognostic (1.75e-2)" "unprognostic (2.41e-1)" "unprognostic (2.50e-3)" "prognostic unfavorable (9.85e-7)" "unprognostic (9.65e-3)" "prognostic unfavorable (7.80e-4)" "unprognostic (2.31e-2)" "unprognostic (4.35e-1)" "unprognostic (1.19e-2)" "unprognostic (1.19e-3)" "unprognostic (9.57e-2)" "unprognostic (3.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.60e-1)" 68.2 112.1 71.2 75.5 74.3 95.0 72.0 73.9 75.2 70.3 81.0 88.7 73.0 57.5 85.5 126.6 76.1 48.7 38.8 70.6 75.1 94.7 92.0 62.1 99.3 72.7 77.2 71.2 113.8 94.2 78.2 85.2 74.0 76.9 84.2 21.8 77.1 57.4 30.0 80.6 63.5 58.9 74.4 86.7 82.6 93.3 77.6 110.2 80.6 27.5 129.1 82.9 75.6 72.1 334.7 229.2 344.3 222.7 153.6 153.7 365.3 224.3 200.7 281.5 240.2 276.9 153.1 323.6 254.7 189.4 152.7 194.9 312.0 318.9 308.5 244.7 321.9 276.3 152.8 273.5 197.7 344.7 241.8 163.4 201.8 244.6 211.0 301.2 260.4 207.0 353.6 95.3 245.9 466.8 339.7 668.7 429.6 224.8 198.2 374.2 144.1 312.9 246.4 420.4 303.9 217.3 262.5 137.3 276.2 222.4 415.9 299.4 229.1 207.8 247.0 157.8 246.3 288.6 234.5 404.9 218.8 255.7 221.5 28.7 16.9 49.3 22.5 19.8 17.5 41.2 17.4 19.9 22.5 36.7 17.3 19.1 19.7 26.5 27.7 30.7 20.1 8.7 71.2 74.3 73.9 75.2 70.6 75.1 72.7 77.2 74.0 74.4 77.6 72.1 172.6 25.6 37.2 17.3 190.1 264.9 269.7 81.2 140.0 74.5 235.6 174.4 1.7 157.3 60.4 161.8 29.2 339.2 204.5 119.5 489.1 200.6 68.5 179.1 149.9 143.8 144.7 141.9 24.1 155.1 469.4 148.9 105.5 143.9 33.7 321.3 132.8 150.0 202.9 72.3 23.6 160.5 63.1 136.3 322.0 28.5 124.5 171.3 200.9 11.2 192.7 134.4 129.8 14.1 24.1 152.4 102.2 155.0 317.8 336.8 89.8 404.3 63.6 55.3 52.6 128.1 165.5 288.5 248.8 218.2 313.4 475.4 158.1 433.1 160.6 392.2 SSR1 TRAPA ENSG00000124783 "Signal sequence receptor subunit 1" P43307 6 7268306-7347446 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011276, HPA017062" Enhanced Supported "Endoplasmic reticulum" NA NA 1600000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA011276: AB_1857503, HPA017062: AB_1857505" "unprognostic (2.27e-1)" "unprognostic (2.10e-1)" "unprognostic (5.98e-3)" "unprognostic (1.57e-2)" "unprognostic (3.10e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.92e-4)" "unprognostic (7.83e-2)" "unprognostic (2.27e-2)" "unprognostic (4.72e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.79e-6)" "unprognostic (3.17e-1)" "unprognostic (2.56e-2)" "unprognostic (6.51e-3)" "unprognostic (2.19e-2)" 64.0 64.4 20.3 89.6 24.6 101.9 70.3 25.4 24.8 88.5 35.7 65.3 65.6 62.7 74.2 71.6 50.8 64.5 41.2 19.0 28.9 58.6 95.5 56.7 68.4 27.6 25.2 67.0 67.9 49.4 25.8 71.5 27.2 59.2 76.4 36.6 79.7 56.0 28.3 42.6 62.4 76.9 23.7 62.4 68.2 38.5 27.8 55.9 84.8 29.1 84.2 74.4 32.8 34.7 122.2 121.7 92.3 171.7 244.9 173.1 144.4 274.5 225.5 183.4 219.1 167.5 98.5 162.9 472.1 282.5 168.3 107.0 112.0 156.6 251.6 172.2 94.6 174.3 130.6 350.7 253.4 325.6 189.6 154.2 169.0 210.2 429.2 140.4 205.2 80.4 199.3 191.1 204.6 146.4 89.6 86.6 78.2 136.5 137.2 120.1 116.0 615.7 161.3 171.5 124.6 57.9 167.0 91.1 263.4 276.8 147.9 141.7 183.1 196.1 149.0 153.3 238.1 195.7 312.1 130.4 95.3 180.4 367.1 146.1 169.5 114.5 82.9 121.9 105.6 73.0 91.7 93.9 199.9 56.1 86.3 86.9 93.3 85.7 110.1 139.3 109.4 214.7 20.3 24.6 25.4 24.8 19.0 28.9 27.6 25.2 27.2 23.7 27.8 34.7 54.0 28.9 48.1 32.3 106.1 77.8 62.1 120.2 69.4 75.4 85.3 46.1 48.5 84.4 93.7 130.6 100.1 78.2 118.6 65.4 15.6 96.0 16.1 48.7 96.0 69.6 62.3 80.8 38.6 103.0 208.5 95.4 68.8 74.3 47.5 64.0 78.1 148.1 130.0 70.7 41.3 130.4 81.4 157.3 251.5 12.4 78.6 129.7 94.3 35.6 131.5 64.1 87.6 49.8 47.8 71.9 47.0 73.0 302.1 111.2 61.5 67.1 57.8 104.2 26.3 57.6 71.6 53.4 58.7 96.0 75.4 121.8 83.6 61.2 93.6 70.4 SST SMST ENSG00000157005 Somatostatin P61278 3 187668912-187670394 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 449.5;intestine: 386.6;pancreas: 479.4;stomach 1: 418.0" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 1404.1;Intestinal goblet cells: 460.2" "Cancer enriched" "Detected in many" 4 "pancreatic cancer: 1039.3" "Region enhanced" "Detected in all" "hypothalamus: 449.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 22.4;U-2 OS: 44.7;U-251 MG: 7.6;U-698: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000075, HPA019472, CAB034105" Enhanced Supported "Secreted to blood" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB000075: AB_2688022, CAB034105: AB_2271061, HPA019472: AB_1857360" "unprognostic (2.44e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.12e-3)" "unprognostic (1.54e-2)" "unprognostic (4.69e-1)" "unprognostic (3.31e-2)" "unprognostic (8.16e-3)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (8.47e-2)" "unprognostic (4.19e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" 5.5 43.0 59.9 4.6 52.1 4.2 0.5 1.3 67.8 0.6 2.5 31.8 386.6 0.7 0.1 1.6 0.4 1.1 1.3 30.6 449.5 6.2 0.3 0.3 1.5 96.9 48.1 2.4 479.4 0.0 9.3 0.1 50.3 1.3 23.8 6.3 0.1 21.6 0.1 8.9 133.3 2.8 137.8 0.2 418.0 0.2 117.2 1.1 1.0 0.0 0.0 7.3 1.8 18.7 0.0 0.0 0.8 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 22.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 44.7 0.4 7.6 0.0 2.9 11.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 52.1 1.3 67.8 30.6 449.5 96.9 48.1 50.3 137.8 117.2 18.7 0.0 0.0 0.0 9.1 0.5 0.0 0.0 3.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 5.5 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.5 0.1 1404.1 0.0 1.7 0.0 0.2 0.7 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 146.2 460.2 215.7 0.0 0.0 0.1 0.0 0.0 0.0 9.4 3.6 0.0 0.0 3.0 9.1 0.0 0.6 0.0 0.0 0.0 11.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.9 13.8 0.2 SSX2IP hMsd1 ENSG00000117155 "SSX family member 2 interacting protein" Q9Y2D8 1 84643706-84690803 "Predicted intracellular proteins" "Cell adhesion, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 118.7;testis: 105.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 260.6;Early spermatids: 774.9;Late spermatids: 1095.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075946 Supported Approved "Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA075946: " "unprognostic (5.18e-3)" "unprognostic (2.13e-1)" "prognostic favorable (1.45e-4)" "unprognostic (2.83e-2)" "unprognostic (2.75e-1)" "unprognostic (3.29e-2)" "unprognostic (1.28e-3)" "unprognostic (7.73e-2)" "unprognostic (2.38e-1)" "unprognostic (3.37e-2)" "unprognostic (9.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (7.23e-3)" "unprognostic (2.08e-2)" "unprognostic (2.45e-2)" "unprognostic (3.46e-2)" 1.9 3.1 8.2 5.8 13.1 14.9 5.1 12.9 23.4 6.8 4.4 8.1 43.2 9.3 22.6 6.4 7.2 8.7 9.4 13.8 3.6 16.5 14.5 3.9 6.4 1.1 1.4 2.0 7.1 9.2 9.6 6.3 1.4 12.7 7.8 118.7 6.9 11.8 3.5 6.5 26.8 10.7 0.0 5.4 7.1 105.7 1.5 12.1 8.2 2.6 6.3 5.7 3.5 11.9 39.1 19.0 15.1 27.7 5.0 15.7 18.4 65.6 33.2 28.3 22.7 13.7 8.4 38.6 11.3 55.8 36.5 21.4 27.0 21.2 39.5 7.7 23.0 36.4 22.2 11.9 10.3 32.1 2.9 6.7 34.1 31.9 20.1 18.9 9.7 14.7 76.5 14.1 18.1 15.0 22.5 12.7 22.3 7.4 29.6 15.1 66.0 17.0 29.5 22.3 29.4 36.7 18.4 29.6 32.9 9.5 17.2 16.4 2.9 26.8 39.2 36.9 65.9 14.7 18.7 42.0 22.4 28.2 16.9 0.8 0.8 3.9 8.2 1.9 4.5 1.2 2.6 3.3 3.5 1.2 3.3 5.1 1.1 4.6 2.6 4.5 1.5 3.9 8.2 13.1 12.9 23.4 13.8 3.6 1.1 1.4 1.4 0.0 1.5 11.9 4.4 3.2 3.0 38.2 3.7 10.5 8.6 8.7 12.5 45.6 10.5 7.0 36.8 21.5 7.3 11.0 260.6 5.3 23.9 3.9 7.9 7.3 774.9 14.9 8.9 5.0 8.4 46.7 108.5 12.0 1.9 15.7 5.6 11.6 4.5 4.2 3.6 14.9 2.7 20.2 70.2 9.3 2.0 1.9 5.6 1095.3 15.8 24.1 5.4 18.7 3.5 187.4 15.5 16.6 23.9 9.4 4.6 11.3 12.7 4.3 19.7 44.9 13.3 158.0 0.0 4.2 7.3 71.7 53.6 13.6 9.8 0.5 8.4 2.0 10.7 4.2 ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 184.1;Early spermatids: 131.4;Excitatory neurons: 191.5;Inhibitory neurons: 176.0;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 115.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA038325: AB_10671740, HPA038326: AB_10672644" "unprognostic (3.40e-2)" "unprognostic (1.04e-1)" "unprognostic (1.33e-1)" "unprognostic (4.70e-2)" "unprognostic (1.09e-1)" "unprognostic (8.18e-2)" "unprognostic (3.32e-2)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (4.45e-3)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "prognostic favorable (3.39e-5)" "unprognostic (1.80e-1)" "unprognostic (1.96e-1)" "unprognostic (8.41e-2)" "unprognostic (3.40e-2)" 13.5 21.7 22.6 6.7 22.0 17.8 15.2 50.6 24.7 19.9 11.1 13.6 12.1 14.5 35.8 9.7 18.6 12.3 22.4 21.8 22.6 29.4 41.3 26.1 7.6 15.0 17.4 17.4 32.9 19.0 24.5 20.9 15.9 13.8 12.4 12.6 21.7 21.2 12.5 11.5 11.0 12.6 14.6 10.4 17.3 8.7 22.5 8.6 28.4 11.2 8.6 12.6 11.1 19.7 29.4 17.2 28.2 24.4 31.0 20.5 12.3 23.0 30.2 24.4 35.2 24.0 32.8 7.7 25.5 21.4 34.7 24.6 24.2 24.5 31.3 11.1 33.9 23.4 26.5 20.2 21.8 27.4 39.4 16.1 24.3 30.7 21.8 21.6 24.9 5.2 36.0 54.6 22.3 18.1 0.2 21.0 26.9 40.1 19.3 6.7 18.8 33.6 25.5 16.2 42.2 33.8 27.8 115.5 32.0 20.6 10.1 23.3 19.1 27.6 11.0 30.5 23.3 34.7 28.2 29.6 22.9 24.0 28.6 1.5 3.1 0.4 7.3 1.2 5.1 2.2 4.4 6.2 5.7 1.0 2.9 3.0 0.0 7.0 1.1 5.6 10.3 3.0 22.6 22.0 50.6 24.7 21.8 22.6 15.0 17.4 15.9 14.6 22.5 19.7 6.3 22.4 38.1 184.1 5.0 7.5 8.6 8.8 10.8 12.2 9.0 7.4 13.5 12.8 12.9 5.5 0.0 21.1 6.4 3.1 5.9 6.0 131.4 7.1 5.9 9.5 3.6 15.8 191.5 13.4 22.8 10.6 12.8 14.2 19.6 3.5 8.6 24.5 8.7 3.3 176.0 6.8 8.2 14.4 6.0 53.5 11.1 7.9 7.2 44.0 7.5 12.8 4.1 111.1 46.9 8.8 3.6 6.0 10.3 6.7 3.6 17.3 6.3 1.3 0.0 9.9 12.1 12.8 5.8 7.4 5.5 21.2 4.6 4.6 5.3 8.8 ST8SIA3 SIAT8C ENSG00000177511 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" O43173 18 57352557-57371731 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.7;pituitary gland: 8.1;retina: 7.5" "Group enriched" "Detected in some" 8 "Bipolar cells: 29.9;Excitatory neurons: 74.9;Horizontal cells: 63.9;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 22.1" "Group enriched" "Detected in some" 11 "glioma: 0.9;pancreatic cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "NTERA-2: 4.4;SCLC-21H: 8.6;SH-SY5Y: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063398, HPA066783" Enhanced Supported "Golgi apparatus" No NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA063398: AB_2685004, HPA066783: AB_2685721" "unprognostic (1.75e-1)" "unprognostic (7.85e-2)" "unprognostic (1.41e-2)" "unprognostic (5.50e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.82e-1)" 0.0 4.3 8.0 0.0 21.7 0.0 0.0 6.7 15.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.9 0.0 12.5 14.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 8.1 0.0 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 9.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 21.7 6.7 15.6 12.5 14.5 0.0 0.0 0.0 0.0 2.1 4.9 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 1.6 5.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.4 2.3 0.0 0.0 0.1 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 63.9 56.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.7 0.0 1.2 0.0 22.1 3.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STMP1 "C7orf73, Mm47, PL-5283" ENSG00000243317 "Short transmembrane mitochondrial protein 1" E0CX11 7 135662496-135693418 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 249.0;Distal tubular cells: 197.6;Extravillous trophoblasts: 261.3;Hofbauer cells: 185.2;Proximal tubular cells: 209.5;Syncytiotrophoblasts: 275.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 431.7;eosinophil: 127.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 431.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065565 Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA065565: AB_2685512" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (3.11e-2)" "unprognostic (3.64e-2)" "unprognostic (1.81e-1)" "unprognostic (2.99e-3)" "unprognostic (1.12e-1)" "unprognostic (4.43e-3)" "prognostic favorable (2.95e-4)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (7.21e-3)" "unprognostic (4.90e-2)" "unprognostic (9.99e-2)" "unprognostic (9.62e-3)" "unprognostic (6.81e-2)" 15.7 28.5 15.5 17.7 17.3 41.3 22.9 15.8 20.5 21.1 17.9 19.8 18.2 16.1 25.7 46.7 15.9 16.6 25.4 15.2 17.2 27.9 32.0 15.2 21.2 17.6 16.4 12.9 15.1 18.5 19.0 19.8 18.1 20.3 22.5 19.2 21.0 15.0 48.4 21.5 19.2 16.4 16.9 14.7 20.4 23.8 16.6 28.8 32.2 32.8 26.2 20.0 27.4 17.6 41.5 19.4 44.9 42.4 52.6 73.2 27.3 44.8 43.5 36.3 37.8 12.0 45.2 38.3 39.3 68.7 35.6 17.0 43.9 57.0 48.9 48.2 36.1 59.4 20.4 28.8 51.7 61.3 36.8 46.0 63.6 43.6 40.4 54.9 30.5 48.5 65.3 33.0 80.9 54.0 87.6 69.5 88.6 57.4 48.5 43.6 48.0 63.0 102.2 21.5 56.6 54.7 60.8 41.3 43.9 43.1 16.9 66.0 51.1 35.3 29.0 63.5 63.2 38.1 58.5 72.9 109.1 63.1 65.9 431.7 57.3 127.7 23.8 61.2 22.8 24.9 22.5 24.3 61.0 21.0 21.0 24.1 44.6 38.9 68.1 34.5 33.1 50.9 15.5 17.3 15.8 20.5 15.2 17.2 17.6 16.4 18.1 16.9 16.6 17.6 67.4 41.7 47.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 128.9 145.3 0.0 0.0 27.9 97.5 0.0 249.0 57.2 0.0 197.6 164.3 0.0 102.2 97.3 39.4 0.0 0.0 0.0 97.4 261.3 43.9 0.0 90.8 56.8 80.1 0.0 0.0 185.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.7 0.0 0.0 146.8 0.0 0.0 0.0 0.0 131.8 0.0 0.0 6.4 0.0 0.0 209.5 34.2 0.0 0.0 0.0 53.0 0.0 0.0 0.0 0.0 275.4 29.8 65.8 0.0 0.0 STRBP "FLJ11307, ILF3L, SPNR" ENSG00000165209 "Spermatid perinuclear RNA binding protein" Q96SI9 9 123109500-123268586 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 415.7;Inhibitory neurons: 256.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 157.0;U-698: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020651 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA020651: AB_1857616" "unprognostic (1.92e-2)" "unprognostic (3.56e-2)" "unprognostic (4.47e-2)" "unprognostic (4.07e-1)" "unprognostic (9.06e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (5.89e-2)" "unprognostic (1.10e-1)" "unprognostic (8.11e-2)" "unprognostic (1.10e-1)" "unprognostic (8.86e-2)" "prognostic favorable (1.70e-10)" "unprognostic (3.25e-2)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (2.13e-1)" 3.9 4.4 4.8 11.5 6.1 14.4 12.6 8.8 17.5 9.1 8.6 17.5 15.4 6.2 18.9 16.3 14.8 6.9 5.5 5.1 6.0 11.7 8.1 6.6 29.5 2.6 5.2 3.8 12.1 37.6 15.3 5.5 2.3 9.0 17.0 22.0 15.8 6.9 5.3 5.5 14.0 5.6 2.2 11.0 11.0 37.6 8.1 24.0 17.6 2.9 35.1 7.4 6.7 8.8 24.7 22.7 30.8 16.6 3.9 2.0 40.6 6.3 1.8 9.6 7.1 24.5 28.6 157.0 13.1 4.9 42.7 22.6 36.3 13.1 15.3 23.1 18.3 33.9 23.9 24.2 7.6 70.4 9.0 1.3 16.1 2.6 11.0 4.4 11.9 46.6 71.6 67.7 2.9 38.2 59.0 31.0 40.8 56.0 17.8 94.5 26.4 51.3 22.8 19.4 45.8 16.5 26.3 28.2 23.0 36.0 37.3 45.3 7.0 1.7 14.3 16.9 19.0 80.4 92.9 141.5 8.5 26.9 11.4 3.8 0.4 1.1 1.3 0.2 1.2 8.1 1.2 1.3 0.4 6.3 1.7 1.3 1.2 2.0 0.6 5.1 1.0 0.7 4.8 6.1 8.8 17.5 5.1 6.0 2.6 5.2 2.3 2.2 8.1 8.8 7.1 19.2 28.8 62.7 94.2 8.9 22.9 7.6 14.8 39.5 29.9 16.1 28.0 21.5 26.0 16.5 87.6 18.3 34.5 33.7 17.6 20.8 80.4 81.5 23.5 9.7 32.4 38.9 415.7 19.0 10.0 5.5 15.8 42.4 12.0 16.7 10.8 15.2 9.8 16.8 256.3 25.2 12.2 2.1 14.0 32.4 5.3 8.3 17.8 88.1 8.2 47.1 5.2 100.5 52.1 18.2 25.7 4.9 52.9 25.3 32.5 17.9 92.5 61.6 0.0 5.5 8.8 128.7 34.4 40.0 10.4 12.9 17.9 5.1 29.8 32.2 STT3A "ITM1, MGC9042, STT3-A, TMC" ENSG00000134910 "STT3 oligosaccharyltransferase complex catalytic subunit A" P46977 11 125591712-125625215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 391.8" "Cell type enhanced" "Detected in all" "Plasma cells: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030735 Approved NA NA 23000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "HPA030735: AB_10603342" "unprognostic (8.25e-3)" "unprognostic (5.45e-2)" "unprognostic (3.02e-2)" "prognostic favorable (1.32e-4)" "unprognostic (5.10e-2)" "unprognostic (1.72e-2)" "prognostic unfavorable (3.57e-4)" "unprognostic (8.40e-2)" "unprognostic (4.80e-2)" "unprognostic (1.16e-2)" "unprognostic (8.96e-3)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.60e-2)" "unprognostic (6.38e-2)" "unprognostic (1.28e-1)" "unprognostic (1.82e-2)" 38.5 39.2 14.6 44.6 17.7 31.8 55.8 17.9 16.9 84.9 29.8 54.0 42.2 60.8 140.4 30.2 56.3 39.5 38.5 15.0 20.1 45.8 69.0 39.0 32.9 19.4 18.4 68.0 69.0 391.8 29.0 63.8 19.6 56.2 59.5 40.0 80.1 77.2 18.4 31.6 42.1 58.9 17.5 34.4 51.4 44.5 17.5 34.8 83.9 24.4 48.8 50.4 33.3 23.1 113.1 99.5 123.7 173.6 230.1 176.4 133.8 198.5 238.5 158.6 196.6 304.2 294.3 143.6 236.2 297.3 222.4 202.7 173.5 176.2 208.5 114.8 90.0 341.0 63.7 215.1 254.4 208.4 153.6 138.4 125.8 219.5 424.5 186.1 182.2 63.9 147.1 210.6 205.4 82.7 84.4 65.6 78.6 221.8 106.0 98.9 107.1 221.5 173.7 170.1 77.5 66.2 142.9 229.3 72.5 144.9 267.8 148.1 164.5 227.7 82.0 97.6 159.7 66.3 82.4 109.6 87.4 206.3 184.7 96.2 46.7 36.6 56.1 45.4 77.9 42.8 53.7 52.0 65.2 32.1 37.1 44.4 15.7 52.8 41.8 158.3 44.0 47.5 14.6 17.7 17.9 16.9 15.0 20.1 19.4 18.4 19.6 17.5 17.5 23.1 17.4 28.9 25.0 6.8 20.8 16.2 14.3 40.3 12.5 11.6 15.2 9.8 23.3 27.1 29.1 16.5 20.9 45.4 21.7 16.1 1.9 30.1 10.6 22.9 51.0 17.3 15.6 19.6 7.6 27.2 73.4 33.0 26.0 57.0 17.1 29.0 32.2 38.5 30.7 1.7 8.9 37.3 20.3 23.6 31.9 5.4 21.5 17.3 24.9 9.4 12.6 13.2 11.3 11.6 10.9 28.6 12.2 18.8 91.9 19.3 15.6 13.6 23.6 15.1 19.7 23.1 32.8 33.5 13.1 21.9 14.8 45.6 14.6 22.3 26.9 13.9 STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 264.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 17000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036448: AB_2675129, HPA036646: AB_10673472" "unprognostic (2.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (7.91e-5)" "unprognostic (1.60e-1)" "unprognostic (3.11e-1)" "unprognostic (2.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-3)" "unprognostic (3.68e-2)" "unprognostic (3.86e-2)" "unprognostic (9.18e-2)" "unprognostic (1.42e-1)" "unprognostic (6.71e-3)" "unprognostic (1.02e-1)" 42.8 59.9 21.1 52.2 29.5 63.7 57.1 23.3 27.0 62.1 30.9 59.7 47.9 51.8 90.3 44.8 45.3 60.2 49.4 22.6 30.7 49.6 74.8 49.3 59.9 24.3 23.1 105.5 45.7 76.6 24.8 60.3 23.9 56.3 61.4 38.6 49.9 51.3 62.1 44.7 49.1 57.7 25.4 44.2 55.1 94.3 26.1 71.8 80.7 57.8 58.8 56.6 32.1 27.6 77.9 128.0 115.4 121.7 142.0 142.3 249.7 142.3 124.9 104.2 119.9 117.7 164.5 134.0 67.8 130.0 85.8 63.9 108.1 123.5 135.9 377.1 70.2 115.0 120.7 126.4 109.4 252.0 131.1 109.8 129.7 148.8 186.7 160.7 107.1 168.3 62.8 209.6 144.0 44.4 246.8 154.8 92.9 129.6 70.7 252.3 62.6 196.0 122.0 110.7 48.7 59.4 141.3 207.2 84.5 98.3 93.4 132.8 209.3 139.8 88.6 139.7 127.3 129.0 166.4 111.4 126.9 170.0 117.6 2.1 3.3 6.2 3.1 3.9 5.0 2.4 5.6 4.4 2.9 2.7 5.3 4.3 1.2 6.1 2.9 5.5 3.0 2.0 21.1 29.5 23.3 27.0 22.6 30.7 24.3 23.1 23.9 25.4 26.1 27.6 32.1 86.6 57.7 34.6 69.6 68.1 58.4 34.1 74.6 51.0 57.2 29.5 71.1 54.3 76.0 44.1 68.8 67.3 65.3 41.8 13.7 34.1 162.8 25.0 65.9 42.0 45.1 50.9 61.5 45.3 100.5 49.6 45.3 43.5 31.1 43.6 37.9 68.2 54.8 45.4 59.4 57.5 36.7 58.0 76.0 264.9 36.4 71.5 51.6 53.4 49.1 34.2 56.7 60.3 73.3 36.5 50.0 32.7 144.2 74.1 50.5 31.5 42.2 37.4 26.3 39.0 53.3 90.9 55.2 65.0 61.8 95.4 78.3 68.4 66.1 69.4 STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" 64.2 30.1 38.1 26.6 39.0 10.8 37.0 40.8 45.6 28.8 25.4 30.7 36.3 30.9 62.9 39.2 23.9 39.8 20.9 37.3 41.7 35.2 29.1 50.0 25.6 42.0 45.3 22.1 30.3 46.5 26.6 33.3 43.6 30.7 32.5 43.2 26.9 32.1 21.4 27.0 32.8 35.9 42.2 30.5 65.5 13.4 38.4 17.3 94.7 27.1 22.2 39.1 23.4 44.6 23.2 10.9 28.8 19.0 53.9 65.0 14.8 47.9 70.3 43.1 48.5 13.5 29.5 25.2 49.6 64.6 18.5 19.0 19.2 23.9 42.9 22.2 22.8 14.4 12.0 13.7 42.2 16.1 29.0 61.3 28.7 60.6 34.5 35.3 70.3 14.3 19.1 24.6 47.7 8.5 13.7 12.3 12.1 34.3 15.3 8.7 23.1 15.5 38.1 37.5 32.3 17.6 22.4 19.3 35.2 23.3 13.1 14.0 76.2 21.9 12.5 50.0 16.6 14.5 11.2 14.3 35.1 24.1 31.2 24.6 35.7 13.7 6.1 39.4 10.6 13.6 7.3 9.7 25.2 10.8 8.1 6.8 16.5 9.2 40.6 12.4 7.9 17.4 38.1 39.0 40.8 45.6 37.3 41.7 42.0 45.3 43.6 42.2 38.4 44.6 93.0 54.5 36.3 25.1 43.6 109.4 97.2 30.7 51.2 46.2 42.0 25.7 18.9 30.0 40.8 57.0 31.3 30.0 28.3 82.8 37.2 51.9 2.0 34.7 33.1 71.1 41.3 17.7 70.9 58.4 33.5 53.2 108.6 49.4 22.8 26.7 47.8 20.4 50.6 26.9 65.7 29.5 14.2 91.4 77.7 4.2 36.1 62.3 53.4 56.2 41.3 67.9 36.0 34.7 59.1 68.4 58.6 47.4 33.9 74.9 51.3 69.7 27.4 51.2 39.5 45.7 57.5 20.0 20.1 69.9 99.2 78.0 31.6 54.0 29.9 99.9 STXBP5L "KIAA1006, LLGL4" ENSG00000145087 "Syntaxin binding protein 5 like" Q9Y2K9 3 120908072-121424761 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 69.0" "Group enriched" "Detected in some" 10 "Excitatory neurons: 1544.2;Inhibitory neurons: 529.4;Oligodendrocyte precursor cells: 390.6" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "cerebellum: 69.0;cerebral cortex: 25.6;hippocampal formation: 19.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.4;HeLa: 4.7;MOLT-4: 6.6;NTERA-2: 3.5;RH-30: 3.3;SCLC-21H: 8.8;SH-SY5Y: 3.9;U-937: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.42e-1)" "unprognostic (9.47e-2)" "unprognostic (6.30e-2)" "unprognostic (2.85e-3)" "unprognostic (1.75e-1)" "unprognostic (2.89e-2)" "unprognostic (7.01e-2)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" "unprognostic (6.73e-3)" "unprognostic (2.52e-1)" "unprognostic (6.52e-3)" "unprognostic (5.13e-2)" "unprognostic (3.58e-1)" "unprognostic (1.86e-3)" "unprognostic (8.61e-3)" 0.0 1.8 3.8 0.0 6.4 0.0 0.0 69.0 25.6 0.6 0.0 1.2 0.3 0.9 0.0 0.3 0.1 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 9.4 0.2 0.0 2.9 0.0 3.8 2.1 0.2 4.3 0.1 3.0 0.0 0.0 0.3 0.8 0.0 0.0 0.4 2.1 0.0 0.0 7.6 0.0 0.0 0.9 0.3 4.4 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 4.7 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 6.6 0.0 3.5 0.0 0.7 0.0 3.3 0.0 0.0 0.6 8.8 3.9 0.0 0.0 0.1 0.0 0.9 2.5 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 1.7 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 6.4 69.0 25.6 19.1 0.0 4.3 0.0 3.8 0.0 0.0 4.4 0.0 0.0 0.0 51.2 0.0 0.1 0.9 0.0 0.0 32.8 0.0 0.0 0.5 0.0 0.0 0.0 75.0 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.3 0.1 12.1 0.0 1544.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 10.1 529.4 0.6 0.0 0.0 0.0 12.8 2.8 0.0 0.0 24.4 0.0 0.8 0.0 390.6 27.9 0.1 0.1 0.4 0.0 0.9 0.0 0.1 0.0 1.1 0.0 0.7 0.3 11.2 7.2 0.0 0.0 0.0 0.0 3.6 0.0 0.2 STXBP6 "amisyn, HSPC156" ENSG00000168952 "Syntaxin binding protein 6" Q8NFX7 14 24809656-25050297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 128.6;Inhibitory neurons: 180.6;Oligodendrocytes: 188.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 48.6;Daudi: 50.7;HBF TERT88: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003552, HPA074869" Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA003552: AB_10603343, HPA074869: " "unprognostic (1.52e-1)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.20e-2)" "unprognostic (9.01e-2)" "unprognostic (2.28e-2)" "unprognostic (1.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.69e-1)" "unprognostic (6.46e-3)" "unprognostic (1.51e-1)" "unprognostic (6.73e-3)" "unprognostic (5.10e-3)" "unprognostic (1.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.36e-1)" "unprognostic (1.48e-3)" 7.3 0.8 18.5 3.8 19.6 0.2 5.0 16.2 27.7 13.5 0.6 11.9 12.3 7.5 38.1 6.0 7.0 11.0 24.7 18.9 21.6 3.6 4.3 26.3 1.6 23.9 23.6 2.8 39.5 23.0 1.0 42.8 17.8 12.7 14.8 2.1 15.0 9.5 4.4 15.0 18.5 5.1 11.4 0.7 9.8 4.4 42.1 7.8 18.0 7.6 5.5 12.3 2.6 19.1 0.1 1.0 2.0 0.5 12.9 22.3 0.2 15.1 40.2 35.5 37.5 48.6 0.3 50.7 0.1 42.6 0.0 0.1 0.0 0.1 64.1 27.2 3.2 12.1 0.4 37.0 9.4 0.9 6.3 3.3 0.0 0.0 0.2 2.0 0.0 1.4 0.5 16.9 34.2 9.7 0.2 0.1 6.6 25.4 0.0 0.0 28.1 0.4 0.0 2.8 2.3 0.1 0.1 7.8 42.6 4.3 0.5 0.7 0.0 6.4 17.2 41.2 2.1 5.1 6.0 2.4 21.8 0.3 24.2 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.2 18.5 19.6 16.2 27.7 18.9 21.6 23.9 23.6 17.8 11.4 42.1 19.1 50.3 51.3 7.7 128.6 0.4 67.7 48.4 0.1 20.5 0.6 2.9 3.3 27.4 64.3 3.4 20.2 0.0 1.4 1.7 12.6 0.0 47.9 20.4 38.8 4.9 35.8 40.7 8.6 72.9 98.7 1.5 44.9 20.4 72.8 42.6 0.8 36.8 5.8 20.1 0.0 180.6 64.6 2.0 1.0 11.0 4.6 1.5 2.9 110.3 113.4 2.0 2.7 0.0 113.6 188.1 39.9 49.6 1.2 3.1 73.9 71.8 9.6 0.0 0.5 0.0 16.4 6.5 12.6 19.7 4.1 48.2 4.0 3.2 0.0 51.7 16.4 SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 232.2;tongue: 271.9" "Cell type enhanced" "Detected in all" "Early spermatids: 256.2;Late spermatids: 314.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA039435: AB_10673144, HPA039536: AB_2676561, HPA061528: AB_2684553" "unprognostic (5.66e-3)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.76e-2)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-1)" "prognostic favorable (7.59e-14)" "unprognostic (3.53e-1)" "unprognostic (2.19e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (1.22e-4)" 53.9 40.6 28.4 20.2 30.8 13.6 38.7 36.6 39.2 32.4 33.6 37.1 58.2 27.2 24.8 33.1 24.7 20.3 100.2 30.7 38.2 77.5 29.0 18.2 22.0 30.6 30.0 30.9 25.4 71.2 20.4 28.1 32.3 35.8 36.3 44.2 33.9 31.3 232.2 20.5 44.7 33.1 30.6 19.9 29.7 17.9 33.8 30.7 36.4 271.9 23.9 26.0 25.3 35.1 44.9 49.5 60.6 37.1 68.4 51.3 38.9 64.8 72.4 66.9 44.5 91.3 47.9 61.3 49.3 63.9 39.9 60.0 81.9 61.9 81.6 59.8 75.9 69.2 45.8 58.0 47.6 69.9 38.9 48.4 71.2 45.3 52.6 54.4 49.0 70.7 47.7 21.1 65.8 31.4 73.1 80.8 64.4 150.2 64.7 60.9 55.4 49.3 94.4 41.9 34.7 41.2 54.5 49.3 39.1 66.5 43.8 60.8 39.0 36.2 24.1 53.0 45.7 23.0 37.4 72.7 22.8 50.9 54.8 12.6 50.2 27.8 34.4 53.7 41.9 34.6 38.0 42.2 62.5 33.1 47.7 47.5 8.8 51.8 46.1 49.8 46.6 36.5 28.4 30.8 36.6 39.2 30.7 38.2 30.6 30.0 32.3 30.6 33.8 35.1 20.8 25.6 16.8 17.6 20.1 32.4 37.7 57.5 21.1 44.8 28.9 26.5 148.8 17.2 40.2 31.3 12.5 48.7 18.1 29.1 164.4 32.3 256.2 50.9 32.0 22.0 19.2 21.0 37.0 17.8 42.7 37.7 19.9 52.6 33.7 25.2 16.1 14.7 29.9 45.4 39.0 19.5 71.2 16.7 20.4 314.2 37.0 21.7 42.7 21.5 24.9 43.3 13.4 26.2 38.2 20.2 30.6 46.3 22.1 35.9 62.3 127.4 29.9 42.4 39.5 33.3 50.0 36.3 29.0 22.8 31.7 52.1 19.7 47.3 30.4 39.0 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SURF1 ENSG00000148290 "SURF1 cytochrome c oxidase assembly factor" Q15526 9 133351758-133356676 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Leigh syndrome, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033946 Uncertain NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "CAB033946: AB_2302648" "unprognostic (1.87e-1)" "unprognostic (7.76e-3)" "unprognostic (1.34e-2)" "unprognostic (4.26e-3)" "unprognostic (3.43e-1)" "unprognostic (2.58e-1)" "unprognostic (1.35e-1)" "unprognostic (7.68e-2)" "unprognostic (3.00e-1)" "unprognostic (4.75e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "prognostic favorable (6.92e-9)" "unprognostic (3.91e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.98e-1)" 41.8 54.3 31.8 9.8 32.9 16.8 39.9 32.3 41.3 33.6 34.2 53.8 18.8 32.8 38.5 34.9 34.5 12.7 70.6 31.0 31.8 59.0 93.1 33.4 16.7 31.9 32.3 31.7 79.4 34.8 41.2 11.9 31.7 42.5 20.8 8.9 42.4 21.4 80.2 41.4 41.1 13.8 32.1 39.9 65.4 33.9 33.8 20.3 43.7 41.2 21.8 45.6 31.8 32.4 9.6 21.8 16.5 23.5 39.7 22.0 35.6 11.5 27.8 18.9 16.5 29.6 32.6 13.0 16.3 18.2 27.6 27.8 20.4 27.6 15.0 23.8 13.3 13.2 31.5 23.4 46.9 21.1 13.5 26.3 47.8 13.2 32.1 23.1 14.9 33.2 13.7 26.3 21.0 42.4 26.7 21.8 18.6 86.9 22.1 18.2 24.7 40.8 31.4 20.4 16.2 45.0 26.2 34.2 30.6 22.4 50.1 15.8 12.2 23.3 14.3 16.1 11.6 32.2 51.9 16.3 22.1 10.3 24.0 10.7 11.6 24.1 6.6 7.8 7.9 23.9 9.8 9.0 10.2 19.3 14.0 7.7 11.1 6.5 7.1 13.4 14.9 5.6 31.8 32.9 32.3 41.3 31.0 31.8 31.9 32.3 31.7 32.1 33.8 32.4 46.2 28.9 29.6 5.2 55.6 46.5 54.9 56.1 43.3 24.4 85.5 97.3 94.6 75.8 44.0 68.0 6.2 93.4 55.7 114.0 137.0 90.4 48.3 54.5 25.2 36.8 53.8 32.2 4.8 101.0 87.5 38.3 41.8 36.9 22.9 44.3 50.3 158.1 101.1 28.6 5.6 74.3 99.7 93.2 83.6 127.1 52.2 60.3 69.4 4.7 96.9 95.2 62.8 4.5 10.4 71.9 102.1 48.2 74.3 56.1 215.0 174.5 45.1 25.3 32.9 41.5 56.6 66.2 94.4 50.4 49.0 80.6 51.5 52.6 79.6 63.4 SYAP1 "FLJ14495, PRO3113" ENSG00000169895 "Synapse associated protein 1" Q96A49 X 16719612-16765340 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000175, HPA000882, HPA048047" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 13000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA000175: AB_1080142, HPA000882: AB_2666128, HPA048047: AB_2680240" "unprognostic (4.66e-2)" "unprognostic (2.99e-2)" "unprognostic (1.25e-2)" "unprognostic (5.44e-2)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (9.53e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.82e-1)" "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (3.95e-3)" "unprognostic (1.14e-2)" "unprognostic (8.10e-2)" "unprognostic (5.28e-3)" 15.3 25.1 5.8 11.2 6.5 25.5 12.4 7.1 7.8 13.1 11.8 14.6 17.4 9.2 8.7 11.3 11.1 13.2 9.5 6.8 7.4 16.0 29.4 9.1 10.3 7.1 6.7 10.9 11.8 15.5 7.6 8.7 7.0 12.8 13.0 7.8 10.7 8.0 12.6 10.3 15.6 9.9 6.6 7.1 13.2 6.4 7.7 7.9 11.5 7.6 10.7 10.8 8.3 8.8 29.2 24.1 17.0 32.0 22.6 25.6 7.8 22.7 16.2 18.6 18.4 22.8 23.5 22.6 32.4 22.3 37.9 16.9 21.0 29.7 24.7 14.8 41.9 9.0 25.4 21.9 16.2 15.5 13.4 17.6 13.7 32.2 27.1 21.5 26.0 6.9 19.8 12.2 25.4 34.2 8.4 16.6 19.9 16.1 26.3 9.1 21.5 22.8 27.8 18.9 17.3 21.3 42.2 29.7 23.1 22.0 39.5 13.8 20.6 23.7 12.5 48.7 18.6 13.4 12.2 26.1 23.3 7.7 19.8 7.4 7.2 9.3 9.9 7.9 8.1 9.0 8.4 9.2 7.8 7.0 8.3 8.7 12.0 10.1 11.4 6.5 10.5 6.5 5.8 6.5 7.1 7.8 6.8 7.4 7.1 6.7 7.0 6.6 7.7 8.8 60.4 64.1 75.6 14.4 96.0 64.1 107.0 69.5 37.0 20.2 116.0 78.2 74.3 88.6 92.2 79.1 22.9 66.5 273.8 164.3 111.6 119.6 214.8 219.3 84.7 53.3 106.1 45.9 13.9 132.1 83.3 65.5 72.4 176.3 210.0 38.3 71.4 216.0 49.5 23.5 16.0 107.4 63.1 70.8 241.0 296.2 42.3 171.5 67.6 8.4 55.7 49.4 64.9 11.6 26.9 183.6 159.2 54.5 185.5 80.3 148.3 164.3 169.7 21.5 59.2 56.9 68.1 15.3 21.5 42.0 52.6 150.5 156.6 48.5 118.6 104.4 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYPL1 SYPL ENSG00000008282 "Synaptophysin like 1" Q16563 7 106090505-106112576 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 633.6;Spermatocytes: 536.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014141 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA014141: AB_1857716" "unprognostic (8.88e-2)" "unprognostic (8.10e-2)" "unprognostic (3.39e-3)" "unprognostic (1.47e-1)" "unprognostic (4.76e-2)" "unprognostic (4.61e-2)" "unprognostic (8.74e-2)" "unprognostic (9.15e-2)" "unprognostic (3.71e-2)" "unprognostic (2.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.32e-1)" "prognostic favorable (1.25e-9)" "unprognostic (2.09e-1)" "unprognostic (1.83e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-1)" 78.7 70.1 35.3 49.2 50.2 51.2 98.3 55.5 63.5 93.6 34.8 83.1 60.4 100.0 88.9 147.2 104.1 70.1 73.3 33.4 41.1 127.2 66.6 66.9 86.0 71.6 50.8 72.1 54.3 125.8 26.3 84.1 69.5 96.8 77.1 13.0 135.8 119.8 149.6 94.0 58.2 109.4 56.2 59.8 81.7 97.6 44.8 56.7 117.4 101.6 121.4 107.5 94.8 82.8 187.1 85.3 44.9 74.4 188.8 142.9 65.0 115.0 128.3 105.8 128.5 58.5 323.6 187.0 150.9 144.2 179.5 154.9 72.4 186.0 174.8 51.6 85.5 82.6 49.5 57.4 148.0 140.7 65.5 107.5 236.7 111.1 142.8 140.9 147.9 69.5 85.5 0.4 212.7 161.3 149.3 167.1 49.8 214.5 112.6 18.4 75.7 97.7 224.4 300.4 22.1 50.1 111.3 266.4 115.6 106.8 81.6 111.0 133.2 210.3 107.3 226.0 132.4 82.1 102.2 193.7 92.6 239.8 121.0 66.9 39.8 44.8 13.6 37.9 28.2 130.3 36.3 27.3 32.5 125.1 53.5 34.3 15.2 71.3 31.2 31.3 33.9 40.9 35.3 50.2 55.5 63.5 33.4 41.1 71.6 50.8 69.5 56.2 44.8 82.8 186.9 54.5 63.4 27.1 238.6 171.7 285.3 326.6 252.6 8.9 111.5 70.4 69.7 181.6 172.9 187.6 16.7 211.6 45.9 51.6 113.5 167.0 633.6 96.6 57.3 153.3 37.8 81.2 8.4 107.5 144.7 125.1 88.7 87.7 91.4 47.9 152.4 96.5 90.5 20.2 7.6 82.7 175.0 83.4 95.3 170.3 95.1 69.4 145.9 16.9 39.4 103.9 15.5 8.5 70.8 130.0 66.2 94.0 23.8 213.6 61.0 221.4 131.2 12.8 157.8 76.3 144.4 536.4 126.3 309.0 173.0 184.0 79.5 113.6 101.1 271.8 SYS1 "C20orf169, dJ453C12.4" ENSG00000204070 "SYS1 golgi trafficking protein" Q8N2H4 20 45361937-45376798 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046716 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA046716: AB_2679769" "unprognostic (8.24e-2)" "unprognostic (1.19e-1)" "unprognostic (5.58e-2)" "unprognostic (1.51e-2)" "unprognostic (1.04e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.10e-2)" "unprognostic (1.63e-2)" "unprognostic (4.77e-1)" "unprognostic (4.66e-3)" "unprognostic (2.33e-1)" "unprognostic (4.28e-2)" "unprognostic (4.90e-2)" "unprognostic (4.38e-2)" "unprognostic (5.38e-3)" "unprognostic (2.01e-2)" 19.7 18.4 15.9 16.4 18.4 25.5 18.2 16.9 16.7 19.2 45.1 21.2 11.6 21.6 17.6 16.1 33.0 18.8 16.5 17.3 18.6 23.6 24.9 19.8 26.7 16.7 17.4 25.1 19.2 23.2 16.4 16.0 17.1 14.9 14.5 21.5 26.1 19.6 23.4 12.7 18.1 16.9 16.0 15.3 20.4 8.5 18.4 16.4 29.8 15.8 24.3 19.0 15.6 19.9 16.8 30.4 12.9 22.0 40.2 24.6 20.4 17.3 24.3 25.5 21.8 76.1 32.0 10.5 39.1 28.7 32.8 35.8 25.6 30.5 17.8 15.1 13.9 12.3 16.6 41.5 33.4 23.0 23.9 30.1 44.6 28.0 17.7 25.6 25.6 18.6 19.3 15.3 18.9 36.6 19.0 23.1 13.8 20.2 42.2 3.1 15.0 16.3 30.6 14.5 9.8 11.8 27.5 16.6 34.2 13.3 37.3 14.6 15.1 32.2 21.3 17.9 16.3 18.1 13.0 4.1 22.0 15.5 18.7 51.8 23.4 37.7 33.8 23.4 35.7 26.3 32.5 34.8 26.4 31.3 35.1 30.6 29.7 22.9 25.6 103.9 37.8 30.6 15.9 18.4 16.9 16.7 17.3 18.6 16.7 17.4 17.1 16.0 18.4 19.9 18.5 19.2 28.1 0.0 39.5 29.1 37.6 24.6 19.9 25.3 29.9 25.4 12.7 27.1 17.3 23.9 29.2 28.4 61.1 31.7 17.6 39.6 30.3 48.7 15.8 23.1 16.1 7.6 0.0 57.9 45.2 26.8 9.2 28.5 26.1 15.0 24.7 34.5 60.6 20.2 0.0 22.6 22.4 38.4 15.4 19.9 17.4 30.3 24.9 0.0 24.4 34.3 35.0 0.0 0.0 42.0 28.5 19.2 14.8 36.2 47.5 29.4 58.4 37.1 13.1 21.0 33.2 17.4 13.8 16.6 30.5 52.5 37.2 18.9 17.1 39.4 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 SYT5 ENSG00000129990 "Synaptotagmin 5" O00445 19 55171196-55180289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 72.6;pituitary gland: 59.3" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Enteroendocrine cells: 57.6;Excitatory neurons: 20.3;Late spermatids: 41.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "EFO-21: 27.1;HMC-1: 60.2;K-562: 22.7;OE19: 95.7;SCLC-21H: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078390 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA078390: AB_2732382" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (9.76e-2)" "unprognostic (4.59e-2)" "prognostic unfavorable (6.54e-4)" "unprognostic (9.85e-2)" "unprognostic (3.24e-3)" "unprognostic (5.94e-2)" "unprognostic (1.36e-3)" "unprognostic (1.82e-1)" "prognostic favorable (5.54e-4)" "unprognostic (1.15e-3)" "unprognostic (3.71e-7)" "unprognostic (7.09e-2)" "unprognostic (5.21e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-1)" 0.2 9.7 40.1 1.9 46.0 0.5 0.1 0.0 72.6 0.8 0.0 2.0 1.3 0.1 0.0 0.2 0.2 0.2 0.2 53.4 58.5 0.1 0.1 0.2 0.2 12.2 20.3 0.0 2.5 0.7 59.3 0.0 22.1 0.1 0.7 4.4 0.0 0.0 0.1 0.8 1.1 0.5 13.3 0.1 1.9 5.4 32.4 0.2 0.1 0.0 0.3 0.1 0.3 39.9 0.2 0.2 0.4 0.4 0.9 0.0 0.3 0.6 0.0 0.0 0.9 0.0 1.1 1.7 27.1 0.0 0.8 0.7 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.1 1.1 0.1 60.2 0.7 0.2 0.0 0.1 0.0 0.5 0.5 22.7 3.8 0.0 0.6 0.5 0.0 0.1 95.7 3.8 0.1 0.4 0.3 0.0 0.1 15.9 7.1 0.0 1.1 0.9 0.0 0.5 0.1 0.1 1.4 1.3 1.7 0.1 0.2 1.4 0.9 0.5 0.1 0.3 1.4 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.5 0.2 0.1 0.1 0.9 0.3 0.1 0.2 0.1 0.1 40.1 46.0 0.0 72.6 53.4 58.5 12.2 20.3 22.1 13.3 32.4 39.9 0.2 0.0 0.0 3.3 1.0 0.6 0.1 1.4 0.0 2.8 0.1 0.6 1.1 0.0 0.4 0.0 4.2 0.0 1.0 0.8 0.0 0.3 15.4 9.1 0.3 0.1 57.6 2.7 20.3 0.4 0.1 0.3 5.6 0.2 0.0 0.7 0.4 0.0 0.2 6.7 11.9 0.8 4.1 0.6 0.0 41.4 0.3 0.1 0.0 3.7 0.1 0.4 0.0 1.5 2.5 0.9 0.1 0.4 0.1 0.1 2.1 0.0 4.0 0.4 0.0 0.0 0.7 8.2 7.6 0.0 0.1 0.0 1.0 0.2 0.6 0.4 SYT9 ENSG00000170743 "Synaptotagmin 9" Q86SS6 11 7238778-7469043 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.9;retina: 7.6" "Cell type enhanced" "Detected in some" "Astrocytes: 48.6;Late spermatids: 23.5;Oligodendrocyte precursor cells: 55.3;Oligodendrocytes: 139.2" "Cancer enhanced" "Detected in some" "breast cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEK 293: 10.3;RT4: 17.9;SH-SY5Y: 13.2;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "unprognostic (1.47e-1)" "unprognostic (9.41e-2)" "unprognostic (1.39e-5)" "unprognostic (1.63e-1)" "unprognostic (1.12e-1)" "unprognostic (5.50e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.64e-2)" "unprognostic (1.81e-1)" "unprognostic (3.31e-3)" "unprognostic (4.35e-2)" "unprognostic (1.92e-4)" "unprognostic (1.22e-4)" 0.0 2.0 9.1 0.0 9.2 0.0 0.8 11.7 5.9 0.4 1.4 0.1 0.0 1.2 0.0 0.0 0.1 0.1 0.3 4.7 7.6 2.0 3.6 0.0 0.0 9.9 11.8 0.1 1.3 0.9 1.5 0.0 9.6 1.0 0.0 7.6 0.0 3.6 0.0 0.1 0.1 0.1 8.1 0.0 0.1 0.9 15.9 0.0 1.1 0.0 0.0 0.2 0.3 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 3.5 0.0 0.0 0.0 0.0 17.9 3.2 13.2 0.0 0.0 0.0 0.4 0.0 0.0 20.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 9.2 11.7 5.9 4.7 7.6 9.9 11.8 9.6 8.1 15.9 11.7 0.0 0.0 0.0 48.6 0.5 0.0 0.1 0.0 0.0 13.6 0.7 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 13.9 0.0 0.2 0.0 0.0 0.0 15.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 3.3 9.8 0.0 0.0 0.3 0.0 23.5 0.0 0.0 0.0 5.6 0.0 2.0 0.0 55.3 139.2 0.0 0.0 0.0 0.0 0.2 0.0 1.5 0.0 3.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TADA3 "ADA3, FLJ20221, FLJ21329, hADA3, NGG1, TADA3L" ENSG00000171148 "Transcriptional adaptor 3" O75528 3 9779860-9793011 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042250 Approved Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA042250: AB_10794043" "unprognostic (5.77e-2)" "unprognostic (1.72e-2)" "unprognostic (2.78e-1)" "unprognostic (2.00e-3)" "unprognostic (6.83e-2)" "unprognostic (4.70e-2)" "unprognostic (9.15e-3)" "unprognostic (2.71e-1)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.47e-2)" "unprognostic (6.56e-2)" "prognostic favorable (5.47e-5)" "unprognostic (1.10e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-3)" 32.5 60.1 51.3 36.9 51.4 34.8 32.5 48.8 57.0 37.9 43.2 44.8 31.4 44.3 23.2 34.2 44.1 32.0 47.2 51.0 54.4 41.6 50.8 34.0 46.3 54.0 53.5 56.8 29.0 35.5 45.0 22.2 50.5 49.6 27.1 18.1 35.5 40.8 59.8 28.6 33.8 32.5 52.4 38.9 39.4 54.5 56.6 32.8 39.3 40.0 37.9 41.6 31.9 48.4 48.0 49.7 78.2 44.2 67.1 61.3 167.6 50.0 83.6 64.3 80.3 50.7 55.1 52.8 59.1 107.7 84.3 28.4 43.9 65.3 29.2 66.0 53.7 118.0 60.6 55.3 95.5 44.6 185.5 62.6 83.3 91.5 65.8 85.0 43.3 75.0 80.6 63.4 80.0 136.0 43.2 44.5 73.5 62.8 47.8 22.2 39.6 67.2 66.3 47.6 30.5 88.5 42.9 23.1 81.5 43.2 80.6 106.2 62.9 88.0 70.4 47.1 70.0 50.3 61.3 92.4 126.0 76.5 74.0 62.8 44.0 126.0 58.2 68.4 30.6 33.8 40.7 48.1 49.6 30.4 35.9 39.2 51.6 53.0 88.9 31.5 54.5 55.2 51.3 51.4 48.8 57.0 51.0 54.4 54.0 53.5 50.5 52.4 56.6 48.4 26.1 12.8 12.8 22.5 37.0 16.8 88.3 66.2 32.5 28.6 43.4 45.7 8.6 41.5 30.2 33.1 14.6 47.3 59.1 80.2 66.5 65.2 93.3 28.7 32.9 24.4 35.5 41.6 9.9 64.2 53.5 34.4 32.1 22.6 47.0 31.9 35.0 43.1 65.0 25.2 10.9 63.0 44.7 50.3 25.4 75.6 36.7 48.8 32.0 6.5 92.8 96.9 146.2 5.0 10.0 67.1 68.2 42.9 31.9 43.1 64.9 70.3 25.2 29.3 72.3 33.9 42.2 86.9 81.2 32.7 16.6 36.8 50.2 41.0 52.7 53.0 TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 400.6;Rod photoreceptor cells: 323.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017160 Approved Uncertain Mitochondria NA NA 520000 "Cluster 18: Basophils - Vesicular transport" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Mitochondria "HPA017160: AB_1851994" "unprognostic (3.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.65e-1)" "unprognostic (3.74e-2)" "unprognostic (5.18e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-1)" "unprognostic (5.86e-2)" "unprognostic (1.00e-1)" "unprognostic (7.38e-2)" "unprognostic (2.76e-2)" "unprognostic (8.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.08e-2)" "unprognostic (4.14e-3)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" 15.4 18.2 33.9 24.9 35.7 41.9 17.1 36.8 38.5 12.7 27.9 23.8 27.1 16.8 12.7 18.2 10.5 19.5 18.5 33.0 38.1 16.2 18.4 23.2 33.8 34.2 35.3 19.3 11.7 15.5 18.7 14.3 33.5 29.0 24.6 48.3 15.2 16.0 21.8 20.3 28.8 17.7 33.6 26.0 25.2 10.7 41.2 31.6 21.1 13.0 33.0 20.6 13.3 42.6 25.7 17.2 12.7 11.1 30.6 37.0 14.5 26.2 29.8 14.9 19.3 8.9 38.5 77.4 8.4 34.9 21.5 22.5 11.2 23.5 23.3 28.3 9.2 91.7 9.0 11.7 35.6 95.2 123.5 25.3 27.7 46.9 68.4 31.3 48.3 45.5 54.3 9.0 27.8 18.2 50.0 62.0 4.7 11.7 9.2 29.1 17.2 8.3 14.1 43.8 2.3 12.5 24.1 10.9 33.6 5.5 22.0 70.0 75.9 25.5 4.5 24.2 22.6 8.7 8.9 60.6 35.8 64.1 35.2 122.3 39.4 91.5 60.9 53.8 58.1 47.9 46.0 53.4 52.4 44.9 40.3 52.9 86.2 86.9 95.4 48.8 46.6 46.0 33.9 35.7 36.8 38.5 33.0 38.1 34.2 35.3 33.5 33.6 41.2 42.6 43.2 35.3 98.9 203.4 110.7 35.2 46.7 30.4 38.1 69.9 52.3 39.6 57.6 52.9 36.7 46.0 212.7 36.1 138.5 116.3 70.5 40.3 18.6 17.5 30.6 36.2 25.1 65.2 117.0 59.1 93.5 37.8 75.4 39.2 167.6 31.6 29.6 57.7 78.5 40.4 156.2 80.7 22.4 104.3 103.0 10.3 38.8 160.5 35.6 133.0 156.9 48.4 217.3 400.6 202.2 91.0 111.7 47.8 84.9 44.4 105.2 37.4 20.7 323.8 46.0 29.9 55.2 101.4 53.3 48.3 31.4 43.8 103.5 66.4 69.3 53.7 TBX21 "T-bet, TBLYM" ENSG00000073861 "T-box transcription factor 21" Q9UL17 17 47733236-47746122 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 11.1;lung: 3.3;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in some" "dendritic cells: 92.8;NK-cells: 119.4;Plasma cells: 22.8;T-cells: 45.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "gdT-cell: 15.7;NK-cell: 14.3" "Group enriched" "Detected in many" 7 "NK-cells: 14.3;T-cells: 15.7" "Cell line enriched" "Detected in single" 113 "HDLM-2: 16.3" "Region enriched" "Detected in single" 27 "olfactory bulb: 22.1" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.2" "CAB009524, CAB030043" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB009524: AB_2200557, CAB030043: AB_1595503" "unprognostic (3.31e-3)" "unprognostic (3.17e-3)" "unprognostic (1.17e-2)" "unprognostic (5.35e-6)" "unprognostic (3.93e-1)" "unprognostic (2.56e-4)" "unprognostic (5.86e-4)" "unprognostic (6.90e-2)" "unprognostic (3.63e-3)" "unprognostic (6.26e-4)" "unprognostic (1.43e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-4)" "unprognostic (7.92e-2)" "unprognostic (2.67e-1)" "unprognostic (9.19e-3)" "unprognostic (4.43e-3)" 0.9 0.4 0.3 1.9 0.3 11.1 0.4 0.3 0.3 0.4 0.4 0.5 0.9 0.3 0.4 0.3 0.4 0.8 0.3 0.2 0.3 0.5 1.2 3.3 7.5 0.4 0.3 0.2 0.2 0.0 0.2 0.2 0.3 0.4 0.5 0.0 0.6 0.2 0.5 0.2 1.6 0.4 0.3 11.7 1.2 0.4 0.3 1.0 0.7 0.2 2.2 0.6 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 3.6 2.0 3.1 8.9 0.0 0.5 0.4 7.8 0.2 14.3 0.0 0.1 0.1 2.4 0.3 0.3 0.3 0.3 0.2 0.3 0.4 0.3 0.3 0.3 0.3 0.3 1.1 0.0 0.6 0.0 7.6 0.0 0.0 0.0 0.6 0.0 0.6 0.9 1.3 1.5 0.0 0.0 0.0 0.1 92.8 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 1.3 0.1 0.0 0.0 0.2 1.1 0.2 2.5 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 1.9 0.0 1.9 0.8 0.0 119.4 0.0 0.1 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.1 0.0 45.6 0.0 0.0 0.0 TBXAS1 "CYP5, CYP5A1, THAS, TS, TXAS, TXS" ENSG00000059377 "Thromboxane A synthase 1" P24557 7 139777051-140020325 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 57.8" "Group enriched" "Detected in many" 4 "granulocytes: 71.0;Hofbauer cells: 88.8;Kupffer cells: 193.6;Macrophages: 132.9;Microglial cells: 191.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 14 "basophil: 324.3;classical monocyte: 322.4;eosinophil: 333.6;intermediate monocyte: 466.0;myeloid DC: 129.0;neutrophil: 271.1;non-classical monocyte: 423.1" "Group enriched" "Detected in all" 22 "dendritic cells: 129.0;granulocytes: 333.6;monocytes: 466.0" "Cell line enhanced" "Detected in many" "NB-4: 76.7;PC-3: 23.7;RPTEC TERT1: 21.0;U-937: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA031257, HPA031258, HPA031259" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 890000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Cytosol" "HPA031257: AB_2673812, HPA031258: AB_2673813, HPA031259: AB_2673814" "unprognostic (4.46e-2)" "unprognostic (3.07e-1)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (2.72e-1)" "unprognostic (9.41e-2)" "unprognostic (5.10e-2)" "unprognostic (3.12e-1)" "unprognostic (2.38e-1)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.52e-1)" "unprognostic (5.00e-3)" "unprognostic (8.53e-2)" "unprognostic (5.34e-2)" 13.2 10.8 5.3 28.1 5.1 24.8 8.2 5.4 5.9 5.4 5.8 10.1 10.3 3.2 2.0 5.4 4.9 21.2 3.3 4.5 6.8 5.8 12.8 23.9 12.4 10.0 6.6 2.9 3.6 2.9 2.3 14.2 8.8 6.4 13.0 1.6 9.0 4.0 1.0 1.3 11.9 12.6 8.9 57.8 11.2 1.4 9.7 15.1 1.8 3.3 8.3 13.9 2.1 14.7 0.2 5.4 0.3 0.1 1.2 3.9 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 12.1 0.0 0.3 0.0 0.0 0.0 0.0 9.4 0.7 17.8 0.0 0.0 1.6 6.2 15.3 2.1 0.0 0.0 0.9 1.1 2.3 0.1 0.6 2.2 0.6 0.2 2.4 76.7 0.2 18.0 23.7 2.6 0.0 1.2 21.0 0.0 0.2 1.1 0.2 0.0 0.8 0.0 0.0 14.4 2.0 0.6 0.2 1.4 1.0 4.6 0.9 0.3 0.4 60.8 1.7 324.3 322.4 333.6 7.3 466.0 11.9 8.3 13.5 3.7 129.0 4.5 2.3 1.3 271.1 11.9 423.1 22.6 13.9 216.7 5.3 5.1 5.4 5.9 4.5 6.8 10.0 6.6 8.8 8.9 9.7 14.7 3.9 3.2 10.8 8.1 9.9 0.4 1.2 0.5 2.8 1.0 3.0 3.0 1.1 5.7 1.7 1.8 6.2 0.6 16.4 0.8 9.8 5.2 0.4 1.0 0.6 5.0 1.8 12.8 1.2 9.5 0.5 2.9 7.1 3.8 71.0 0.5 16.8 8.6 88.8 3.3 1.8 1.9 12.2 193.6 19.5 0.7 0.3 132.9 3.6 191.1 63.7 4.9 26.8 3.0 5.9 4.4 7.9 0.0 16.4 5.8 0.2 6.3 1.0 4.1 19.7 1.3 1.7 0.5 0.7 26.2 0.6 0.5 13.4 0.3 2.7 1.2 TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA043786: AB_10959468" "unprognostic (5.35e-2)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (2.11e-3)" "unprognostic (3.34e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (1.77e-1)" "unprognostic (4.14e-2)" "unprognostic (1.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.80e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" 52.7 46.0 44.1 56.5 47.5 81.2 62.2 44.7 58.3 55.3 42.5 49.7 47.1 55.6 45.8 53.9 52.4 42.6 35.9 42.0 46.0 59.8 90.4 46.7 98.3 47.2 44.6 61.9 68.4 80.0 28.2 49.3 47.0 59.0 50.7 49.0 56.5 54.2 42.0 49.8 46.9 52.4 47.5 49.5 52.2 36.8 44.2 72.4 124.2 41.7 112.6 54.6 41.4 55.1 161.3 157.9 138.1 145.7 99.3 121.8 100.9 122.1 147.3 143.5 160.2 91.4 131.0 392.5 136.9 147.0 152.5 120.9 182.3 116.6 212.9 225.0 88.5 293.6 71.5 139.5 309.7 116.8 122.7 88.5 308.1 137.4 606.2 121.3 128.2 132.9 191.1 334.0 135.5 75.6 245.8 83.3 229.1 265.0 47.1 185.1 48.2 72.5 204.0 107.0 129.9 95.5 101.9 91.0 356.3 132.2 129.6 132.6 110.6 106.1 96.3 120.6 114.5 201.1 134.4 260.9 184.9 133.2 152.1 82.3 64.1 78.7 103.9 63.1 98.3 213.8 107.0 96.7 81.8 174.1 93.9 99.3 23.1 97.5 60.6 116.7 153.0 73.5 44.1 47.5 44.7 58.3 42.0 46.0 47.2 44.6 47.0 47.5 44.2 55.1 94.7 89.8 106.2 24.2 253.2 135.5 128.3 98.9 257.2 77.0 129.2 124.3 23.9 82.9 109.4 99.3 89.6 115.5 143.8 61.0 168.3 121.0 86.4 126.9 145.4 92.5 87.2 330.7 17.7 109.9 125.1 118.8 111.6 124.4 98.7 75.7 66.4 160.7 87.7 57.2 20.1 96.6 118.0 89.5 134.2 191.0 134.8 124.2 117.4 17.8 132.5 166.0 170.0 22.1 29.7 121.1 71.6 132.8 341.1 146.0 72.2 207.6 110.6 104.5 78.9 102.6 130.4 94.9 103.1 237.2 150.6 112.1 154.8 108.5 88.1 148.6 TCEAL8 "MGC45400, WEX3" ENSG00000180964 "Transcription elongation factor A like 8" Q8IYN2 X 103252995-103255192 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059115 Uncertain Approved Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA059115: AB_2683909" "unprognostic (1.51e-2)" "unprognostic (4.56e-2)" "unprognostic (9.24e-2)" "unprognostic (7.13e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.71e-3)" "unprognostic (1.88e-2)" "unprognostic (5.52e-2)" "unprognostic (4.80e-3)" "unprognostic (4.03e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (3.26e-2)" "unprognostic (7.22e-2)" "unprognostic (9.12e-2)" "unprognostic (9.32e-2)" 42.9 62.6 51.9 36.3 53.1 29.3 60.0 55.0 69.6 67.2 53.8 47.9 30.5 58.3 131.1 38.8 45.3 57.1 93.1 53.1 54.6 69.4 42.7 43.9 47.6 53.4 52.2 69.4 40.9 71.0 56.5 62.2 53.9 59.2 49.5 33.2 61.5 56.1 18.8 39.3 40.4 63.2 55.1 45.8 42.0 42.9 53.4 71.9 71.3 32.0 45.7 57.3 36.5 55.9 49.2 26.4 110.9 51.8 161.9 269.3 53.2 104.9 154.7 90.6 141.0 20.6 94.5 25.8 68.2 120.7 157.7 32.1 19.6 120.0 116.5 0.4 61.5 111.2 34.5 30.8 98.8 114.4 105.6 184.9 68.0 79.5 0.0 190.3 123.9 75.3 135.0 23.8 223.6 0.0 98.2 43.9 123.2 4.4 52.7 37.1 152.8 7.6 124.7 36.4 57.7 75.4 58.3 18.1 130.8 105.7 33.9 38.0 83.1 53.5 71.0 164.4 35.2 26.2 49.8 1.1 86.7 61.0 87.6 73.7 31.9 20.0 66.3 29.3 76.6 62.4 78.1 71.4 58.2 52.6 84.5 73.5 3.0 120.6 23.2 101.3 109.5 54.5 51.9 53.1 55.0 69.6 53.1 54.6 53.4 52.2 53.9 55.1 53.4 55.9 72.3 51.3 66.7 6.8 32.7 60.8 83.9 169.4 68.9 52.3 70.5 69.2 76.6 104.4 89.4 97.5 10.4 188.8 48.5 27.5 273.9 137.8 6.8 46.2 71.8 85.0 78.5 33.2 10.3 109.4 176.3 93.9 29.6 49.7 69.6 76.2 169.6 102.5 98.7 50.5 10.0 133.7 81.4 90.6 81.1 17.2 125.9 52.4 120.9 10.3 71.4 110.4 104.0 7.1 11.3 68.2 49.2 121.9 27.2 51.3 73.5 276.2 60.1 37.5 85.5 80.6 77.4 5.6 4.0 47.6 59.5 134.9 45.1 68.1 78.7 79.5 TCF20 "AR1, SPBP" ENSG00000100207 "Transcription factor 20" Q9UGU0 22 42160013-42343616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 127.0;Inhibitory neurons: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017849, HPA036786" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "CAB017849: , HPA036786: AB_2675313" "unprognostic (2.17e-1)" "unprognostic (2.12e-2)" "prognostic favorable (1.88e-4)" "unprognostic (2.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (4.89e-4)" "unprognostic (1.77e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-3)" "unprognostic (7.30e-2)" "unprognostic (1.17e-3)" "unprognostic (3.07e-3)" "unprognostic (4.94e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 7.1 6.5 4.2 1.7 3.1 1.6 7.5 0.0 2.9 10.2 0.0 9.1 1.6 9.0 0.2 16.3 6.9 1.0 4.9 3.7 2.4 7.6 7.4 7.1 1.6 0.9 1.0 7.6 8.2 1.2 7.4 1.2 1.1 6.9 1.3 0.9 9.9 1.0 5.7 14.3 10.0 1.4 0.0 7.3 8.0 15.3 1.8 2.3 9.6 1.3 1.6 7.8 11.0 2.1 6.6 2.3 3.2 2.1 1.0 2.1 5.5 4.2 2.8 2.1 3.5 5.0 2.5 10.9 3.6 1.1 3.1 5.4 3.9 3.3 1.2 8.5 3.9 3.4 2.2 1.6 1.5 6.0 4.7 1.2 2.9 3.0 3.0 0.9 1.0 3.1 4.1 3.9 1.6 3.0 9.4 1.8 3.4 2.2 3.1 4.7 2.0 5.7 0.5 5.2 6.2 2.0 2.7 2.0 2.7 2.0 1.2 4.8 3.9 3.8 8.9 3.9 1.9 7.0 6.2 4.5 2.3 4.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.1 0.0 2.9 3.7 2.4 0.9 1.0 1.1 0.0 1.8 2.1 10.0 0.0 9.6 23.5 9.1 22.6 11.3 19.4 12.0 25.1 11.5 6.9 7.3 17.2 10.1 9.2 18.8 6.3 11.0 16.6 0.0 10.8 127.0 14.2 9.9 9.3 16.8 9.9 54.0 7.5 5.5 8.1 10.7 22.2 1.3 10.0 8.9 12.6 6.2 10.1 63.5 13.8 12.2 12.4 13.3 36.2 12.5 9.4 7.2 22.5 12.0 5.6 6.2 29.7 55.0 13.3 13.5 6.4 8.7 20.9 13.0 6.0 13.4 12.6 6.6 5.8 8.5 19.1 13.4 19.5 22.9 4.5 13.0 4.3 17.9 14.6 TCTA ENSG00000145022 "T cell leukemia translocation altered" P57738 3 49412206-49416475 "Disease related genes, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007342 Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "HPA007342: AB_2202399" "unprognostic (5.58e-2)" "unprognostic (4.33e-2)" "unprognostic (6.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.17e-2)" "unprognostic (3.35e-2)" "unprognostic (2.18e-1)" "prognostic favorable (6.76e-4)" "unprognostic (3.74e-1)" "unprognostic (3.38e-3)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (5.00e-15)" "unprognostic (1.68e-1)" "unprognostic (1.96e-1)" "unprognostic (3.43e-1)" "unprognostic (6.41e-3)" 21.7 48.0 49.1 13.1 52.3 12.3 21.5 50.1 52.9 23.2 47.0 24.7 18.9 23.1 60.6 15.6 26.1 16.6 22.6 48.4 50.6 51.0 41.9 23.5 15.8 51.6 51.6 27.1 24.1 39.8 48.8 14.5 52.3 34.5 28.8 14.0 21.8 25.1 19.6 14.2 23.1 21.8 48.8 25.9 23.3 15.7 52.1 20.1 45.3 13.8 16.0 25.4 15.9 51.5 12.8 15.5 9.8 14.8 42.5 18.5 12.9 26.0 19.2 25.8 21.6 9.1 13.6 15.2 18.6 61.5 29.6 14.4 19.3 26.2 21.0 22.9 13.4 25.4 19.6 11.9 25.8 10.9 31.9 40.2 26.8 28.7 22.9 24.7 27.0 12.0 9.4 33.8 63.8 11.7 13.4 9.8 8.0 24.1 35.5 8.1 10.6 36.0 44.5 16.7 26.3 8.7 30.9 33.8 28.6 19.7 28.8 10.2 24.5 19.3 11.9 40.4 9.8 18.4 26.1 10.4 45.4 19.3 27.2 20.4 17.8 23.2 19.1 34.2 11.1 12.0 12.0 14.7 10.1 13.7 14.9 15.5 20.1 23.0 47.5 15.6 17.8 22.4 49.1 52.3 50.1 52.9 48.4 50.6 51.6 51.6 52.3 48.8 52.1 51.5 15.5 25.6 15.6 8.8 19.3 2.7 10.0 10.3 14.2 10.2 19.9 18.0 14.1 20.0 12.9 27.6 12.5 25.9 20.5 34.0 46.9 15.3 8.0 15.5 15.0 14.7 17.5 9.0 12.3 11.6 11.5 17.6 53.5 17.0 5.7 7.1 11.4 31.8 24.8 10.1 11.0 19.1 20.3 18.6 6.0 14.3 15.5 19.2 14.2 11.2 15.5 26.3 26.8 11.1 16.8 15.1 28.6 16.1 13.2 13.4 34.9 50.3 22.8 11.3 6.6 13.7 16.6 8.2 6.1 10.4 4.5 20.0 21.6 22.1 16.6 7.9 TDRD9 "C14orf75, DKFZp434N0820, FLJ36164, NET54" ENSG00000156414 "Tudor domain containing 9" Q8NDG6 14 103928456-104052667 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "parathyroid gland: 30.6;testis: 40.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 43.2;Spermatocytes: 63.2;Spermatogonia: 38.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 1.6" "Lineage enriched" "Detected in single" 6 "monocytes: 1.6" "Cell line enhanced" "Detected in some" "HDLM-2: 24.4;HeLa: 21.5;HMC-1: 94.2;RPTEC TERT1: 25.5;SK-MEL-30: 13.3" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.71e-1)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (1.91e-1)" "unprognostic (1.55e-1)" "unprognostic (2.74e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-4)" "unprognostic (1.60e-2)" "unprognostic (4.57e-3)" "unprognostic (8.97e-2)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.41e-2)" 0.4 0.5 0.9 0.6 0.8 1.7 0.5 1.3 0.9 0.4 1.2 0.3 0.1 0.4 0.4 0.2 0.9 0.9 0.6 0.8 0.8 2.1 0.3 1.0 0.5 1.7 1.0 0.2 0.5 30.6 1.0 0.5 2.0 0.3 0.2 3.5 0.3 0.5 0.1 0.1 0.3 0.5 1.1 3.0 0.8 40.7 1.1 0.3 5.4 0.5 0.5 0.4 0.2 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.4 0.0 0.0 21.5 0.0 0.0 0.0 94.2 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 8.7 0.0 0.0 0.6 13.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.8 1.3 0.9 0.8 0.8 1.7 1.0 2.0 1.1 1.1 1.3 0.9 6.4 2.0 2.3 0.0 0.0 0.1 0.1 0.0 4.3 1.0 0.4 12.4 0.0 0.7 0.0 4.2 0.0 0.5 0.0 1.9 0.6 13.1 43.2 1.5 0.9 0.0 1.3 9.1 0.0 0.0 0.7 0.0 3.7 0.0 0.3 0.4 0.1 1.9 6.7 4.6 0.0 2.0 1.8 0.0 7.3 0.9 1.5 0.0 2.8 2.9 0.6 0.0 1.0 4.6 0.5 0.0 2.2 0.3 0.5 0.0 2.5 0.2 2.3 6.6 0.9 0.8 63.2 38.6 0.0 0.0 0.0 0.3 11.7 0.0 0.1 TENM3 "KIAA1455, ODZ3, Ten-M3, TEN3" ENSG00000218336 "Teneurin transmembrane protein 3" Q9P273 4 182143987-182803024 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.8;placenta: 13.1" "Cell type enriched" "Detected in many" 4 "Inhibitory neurons: 635.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 66.3;BEWO: 63.3;HDLM-2: 90.0;T-47d: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047043 Approved Approved Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA047043: AB_2679914" "unprognostic (5.79e-2)" "unprognostic (3.01e-2)" "unprognostic (6.62e-2)" "unprognostic (4.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (8.28e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (4.85e-2)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (8.59e-2)" "unprognostic (1.07e-2)" "unprognostic (5.25e-4)" 5.0 5.1 12.0 1.6 18.4 0.0 2.0 0.0 12.3 1.5 0.0 4.3 0.8 2.9 0.6 0.8 1.0 2.4 1.4 21.8 8.1 0.9 0.3 0.8 0.8 2.8 7.3 3.8 1.2 5.1 4.5 13.1 0.0 3.7 0.8 3.9 0.6 3.6 2.1 0.4 0.9 2.3 0.8 2.2 0.7 2.1 7.4 2.8 6.1 4.3 1.2 1.6 1.4 2.0 0.3 2.6 66.3 0.4 13.2 23.5 63.3 7.8 2.7 6.9 6.1 33.9 17.6 0.0 0.9 52.6 28.6 3.3 16.0 3.4 6.8 90.0 26.7 0.0 0.0 0.0 1.3 0.0 0.0 31.2 1.2 21.5 15.0 15.4 9.6 0.0 0.0 0.4 10.6 2.3 0.1 0.1 21.4 0.0 2.8 0.0 17.1 0.2 0.1 0.1 27.2 25.2 4.0 0.5 0.1 35.8 86.0 3.4 21.2 53.7 38.2 0.2 39.6 0.0 0.0 0.0 28.2 0.0 40.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 18.4 0.0 12.3 21.8 8.1 2.8 7.3 0.0 0.8 7.4 2.0 0.1 0.0 0.0 23.8 0.0 0.4 0.2 0.7 1.8 50.8 1.6 2.2 3.9 0.0 0.1 3.7 4.2 112.7 0.0 0.0 1.9 0.1 12.4 0.1 4.5 0.7 5.3 0.0 115.6 1.8 54.6 4.1 0.0 0.6 0.0 7.7 1.1 0.7 10.4 5.0 635.6 0.0 0.0 0.0 0.7 3.2 8.4 0.0 1.8 8.4 0.0 10.6 0.0 12.1 24.4 0.4 0.0 2.6 0.0 0.4 0.0 0.3 0.0 3.1 0.0 4.8 3.2 3.8 7.2 1.8 0.0 133.4 0.1 4.1 0.1 0.1 TEX2 "HT008, KIAA1738, TMEM96" ENSG00000136478 "Testis expressed 2" Q8IWB9 17 64147227-64263260 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5;Late spermatids: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "plasmacytoid DC: 20.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 20.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020648, HPA057116" Approved Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA020648: AB_1857908, HPA057116: AB_2683341" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "prognostic favorable (3.90e-6)" "unprognostic (1.69e-2)" "unprognostic (3.84e-2)" "unprognostic (8.34e-2)" "unprognostic (6.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.53e-1)" "unprognostic (8.39e-2)" "unprognostic (1.11e-1)" "unprognostic (7.97e-2)" "unprognostic (7.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.53e-3)" "unprognostic (5.59e-3)" 16.6 24.2 38.4 7.3 46.9 18.7 19.6 38.3 39.3 17.8 31.1 13.6 10.2 14.7 11.4 17.3 13.4 16.7 27.2 37.6 46.2 18.5 33.2 14.9 6.3 43.5 46.4 15.7 29.4 31.5 11.2 9.9 43.3 16.3 13.5 23.0 19.4 17.0 45.0 15.5 10.2 14.6 40.4 12.7 13.2 53.5 44.9 8.9 40.2 41.9 6.8 10.5 11.1 44.2 32.6 15.2 9.5 19.5 44.7 26.3 11.5 44.1 49.7 39.2 27.0 14.2 7.8 11.3 11.0 55.9 24.3 15.5 17.0 53.3 44.7 16.6 11.6 76.3 9.9 27.0 16.7 22.5 12.2 19.3 29.0 26.7 54.3 27.5 19.1 18.8 21.3 13.6 29.8 36.1 20.5 10.4 5.4 25.3 26.9 12.6 85.8 16.1 22.7 14.9 14.4 24.0 21.9 55.9 24.3 52.2 26.4 19.0 22.6 36.5 21.1 28.5 25.8 14.0 20.1 7.2 14.5 21.0 33.6 0.0 3.1 0.9 1.5 1.0 1.7 0.3 1.7 1.8 2.9 0.6 1.7 1.7 0.3 3.3 2.0 20.6 1.3 1.8 38.4 46.9 38.3 39.3 37.6 46.2 43.5 46.4 43.3 40.4 44.9 44.2 8.1 3.2 8.1 27.4 3.4 8.8 6.8 5.1 16.5 4.2 17.6 13.7 33.3 8.6 6.2 12.9 6.2 2.5 14.7 10.7 1.9 4.7 53.5 6.0 10.5 8.8 12.1 15.4 41.6 8.3 2.0 7.4 16.3 4.2 3.8 12.2 8.6 30.4 12.0 10.1 35.6 11.3 6.1 11.5 3.7 52.9 6.5 9.2 7.2 17.8 2.9 7.2 1.0 33.2 39.3 6.5 4.6 12.8 10.1 7.1 7.1 8.3 8.2 17.3 0.0 12.6 7.4 22.5 8.8 14.6 8.9 1.4 3.6 9.4 10.9 5.4 TEX264 "FLJ13935, ZSIG11" ENSG00000164081 "Testis expressed 264, ER-phagy receptor" Q9Y6I9 3 51662693-51704323 "Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 374.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005002, HPA017739" Enhanced Approved Nucleoli,Cytosol "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoli, Cytosol" "CAB005002: AB_425976, HPA017739: AB_1857910" "unprognostic (2.80e-3)" "unprognostic (1.05e-2)" "unprognostic (2.69e-1)" "unprognostic (2.79e-3)" "unprognostic (8.11e-2)" "unprognostic (8.26e-3)" "unprognostic (2.05e-1)" "unprognostic (3.06e-3)" "unprognostic (2.30e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.83e-1)" "prognostic favorable (7.95e-9)" "unprognostic (4.99e-2)" "unprognostic (3.65e-1)" "unprognostic (3.17e-1)" "unprognostic (4.67e-2)" 34.7 73.4 43.5 23.1 46.5 22.3 35.6 48.7 51.7 39.0 53.1 41.5 39.0 34.2 41.2 41.1 44.0 39.7 41.4 43.8 47.2 67.6 65.3 29.8 33.5 47.2 45.5 31.3 54.3 88.5 26.2 29.4 46.4 45.1 34.5 20.4 58.7 46.9 34.2 69.3 37.6 26.3 46.3 40.9 46.7 111.5 45.9 29.1 48.7 29.6 26.3 35.9 34.9 48.4 36.5 65.5 11.6 59.3 116.8 56.4 23.5 31.0 72.0 50.1 50.1 35.2 84.2 51.6 21.9 44.1 84.2 34.7 32.7 61.6 23.7 42.0 51.9 49.6 40.2 47.8 104.0 31.5 53.6 74.8 96.9 56.3 57.1 45.3 36.9 39.0 26.6 87.7 51.9 42.1 50.9 73.3 12.6 59.8 72.7 24.3 15.3 98.7 79.7 50.1 16.5 26.8 37.4 101.5 48.0 15.7 49.6 66.0 27.3 49.8 20.8 53.0 41.2 61.0 71.3 26.4 61.5 65.9 50.9 99.2 110.1 69.3 119.7 115.6 120.3 98.6 122.6 113.6 104.6 102.4 100.9 103.1 23.5 76.1 115.6 92.4 159.9 139.9 43.5 46.5 48.7 51.7 43.8 47.2 47.2 45.5 46.4 46.3 45.9 48.4 63.6 35.3 21.9 12.4 36.7 34.8 46.7 123.9 45.5 33.5 69.9 68.2 24.4 65.8 68.2 99.3 58.4 142.9 52.3 70.3 62.6 83.1 57.7 44.9 31.8 54.8 32.9 24.8 6.5 75.7 88.9 41.4 29.0 48.2 16.5 45.3 38.9 63.1 105.4 42.1 9.1 56.5 118.0 48.3 45.5 61.2 51.0 47.8 65.8 8.4 56.1 62.6 89.6 7.5 12.3 59.6 76.4 48.9 36.0 45.6 137.6 126.7 49.7 55.4 26.3 30.8 30.7 374.8 111.7 46.3 35.4 76.3 61.9 110.4 86.0 49.9 TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.1;salivary gland: 97.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 79.1;Distal enterocytes: 117.9;Glandular and luminal cells: 83.0;Ionocytes: 262.4" "Cancer enhanced" "Detected in many" "testis cancer: 21.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.2;HEL: 15.7;hTCEpi: 17.3;RPTEC TERT1: 42.4;RT4: 31.8;SCLC-21H: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" Mitochondria "HPA029708: AB_10602479" "unprognostic (8.85e-3)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.25e-2)" "unprognostic (2.72e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "prognostic favorable (7.72e-6)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (6.67e-3)" "unprognostic (2.01e-1)" 1.9 0.3 0.9 1.7 1.6 0.2 28.7 1.7 1.1 18.1 19.0 19.0 0.6 0.5 8.3 13.3 3.5 2.9 0.2 1.7 0.9 49.1 0.2 5.6 0.2 1.6 2.1 0.1 6.4 2.6 0.8 7.4 1.1 13.6 22.6 0.0 97.5 2.0 2.6 31.9 3.2 0.6 0.7 1.8 16.3 1.1 1.9 0.2 37.6 0.1 1.2 1.8 10.9 0.7 0.0 1.6 0.0 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.7 0.0 0.7 0.4 4.4 4.5 0.0 0.0 3.2 15.7 0.0 0.0 0.0 0.0 0.6 0.0 17.3 0.0 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.9 0.1 0.0 0.5 2.1 42.4 31.8 13.3 0.1 1.7 0.1 0.0 6.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.7 1.1 1.7 0.9 1.6 2.1 1.1 0.7 1.9 0.7 0.1 6.4 28.8 3.9 0.3 1.7 38.0 10.3 28.5 0.0 22.1 11.6 2.6 17.2 35.4 79.1 0.0 32.2 0.9 117.9 31.3 2.7 0.1 43.5 5.8 1.0 10.2 0.0 0.2 1.5 2.3 0.8 58.6 83.0 0.0 1.2 0.0 0.4 4.9 0.0 0.3 31.2 262.4 4.6 0.8 0.5 0.3 5.5 7.2 9.4 0.2 0.5 0.0 0.0 0.1 7.4 28.0 0.0 2.1 36.3 0.3 27.7 11.9 0.0 0.0 1.9 1.1 0.1 1.5 41.0 3.3 20.2 1.1 9.5 44.3 40.7 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 THEMIS "bA325O24.3, bA325O24.4, C6orf190, C6orf207, FLJ40584, TSEPA" ENSG00000172673 "Thymocyte selection associated" Q8N1K5 6 127708072-127918631 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 47.1;Microglial cells: 15.0;T-cells: 59.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 22 "gdT-cell: 26.7;MAIT T-cell: 34.0;memory CD4 T-cell: 33.5;memory CD8 T-cell: 48.9;naive CD4 T-cell: 30.0;naive CD8 T-cell: 58.3" "Lineage enriched" "Detected in single" 88 "T-cells: 58.3" "Group enriched" "Detected in some" 4 "HDLM-2: 32.6;JURKAT: 54.1;MOLT-4: 51.6;RPMI-8226: 21.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031422, HPA031425" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Nucleoplasm "HPA031422: AB_2673874, HPA031425: AB_10670129" "unprognostic (1.47e-4)" "unprognostic (2.50e-3)" "unprognostic (1.31e-2)" "unprognostic (1.41e-4)" "unprognostic (1.41e-1)" "unprognostic (5.20e-3)" "unprognostic (7.48e-3)" "unprognostic (9.01e-3)" "unprognostic (1.47e-1)" "unprognostic (7.41e-3)" "unprognostic (1.24e-1)" "unprognostic (1.28e-1)" "unprognostic (2.65e-4)" "unprognostic (2.04e-1)" "unprognostic (3.91e-2)" "unprognostic (4.98e-2)" "unprognostic (1.60e-2)" 0.4 0.5 0.5 3.3 3.2 1.7 0.6 0.1 2.3 0.4 0.3 0.7 1.6 0.2 0.4 0.6 0.2 1.4 0.1 0.9 0.1 0.2 0.7 1.4 7.5 0.6 0.3 0.1 0.3 0.0 0.0 0.1 0.4 0.4 0.9 0.0 0.9 0.1 0.1 0.2 2.3 0.3 0.3 3.2 1.5 0.1 0.3 32.9 0.4 0.1 4.0 1.1 0.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.0 0.0 0.0 0.0 51.6 0.0 0.0 0.0 0.0 0.0 0.0 21.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 26.7 0.1 34.0 0.1 33.5 48.9 0.2 0.2 30.0 58.3 0.6 0.1 0.2 0.2 1.7 20.3 0.5 3.2 0.1 2.3 0.9 0.1 0.6 0.3 0.4 0.3 0.3 1.9 0.5 0.0 3.0 2.9 2.0 0.5 0.0 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.9 0.1 0.2 0.4 0.0 1.7 47.1 0.0 0.0 0.7 5.1 0.1 1.3 0.0 1.1 0.1 0.1 0.0 0.9 0.0 0.0 0.8 0.8 0.2 0.0 1.5 7.2 15.0 1.4 0.0 0.0 0.0 9.7 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.1 0.0 0.1 1.4 0.0 59.9 0.0 0.0 0.1 TIFA "MGC20791, T2BP, T6BP, TIFAA" ENSG00000145365 "TRAF interacting protein with forkhead associated domain" Q96CG3 4 112274537-112285904 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 86.6;Syncytiotrophoblasts: 79.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 137.4;U-698: 123.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045889 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli" Cytosol "HPA045889: AB_10963785" "unprognostic (2.41e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.86e-1)" "unprognostic (4.98e-3)" "unprognostic (1.05e-1)" "unprognostic (2.25e-1)" "unprognostic (2.48e-2)" "unprognostic (2.14e-2)" "unprognostic (4.60e-3)" "unprognostic (5.26e-2)" "unprognostic (6.44e-3)" "unprognostic (1.52e-1)" "unprognostic (2.56e-1)" "unprognostic (2.99e-1)" "unprognostic (8.49e-3)" 6.4 6.3 2.0 19.9 1.8 40.6 13.7 4.3 2.1 7.7 4.3 7.0 6.7 5.6 2.1 15.6 6.8 7.5 10.7 2.3 2.4 5.2 11.3 10.2 32.2 2.3 2.1 9.3 41.3 11.5 2.1 14.2 2.5 6.7 6.9 2.8 34.8 3.7 3.8 9.3 8.8 5.3 2.1 11.7 10.3 2.1 2.3 15.4 21.1 6.4 34.6 11.6 7.7 2.3 21.9 5.5 7.9 13.4 9.5 7.7 15.9 17.0 32.0 10.6 18.1 2.8 19.1 66.3 13.5 6.8 15.5 6.3 10.9 13.0 22.1 54.1 6.4 6.6 12.4 6.2 6.4 21.2 8.8 10.4 7.0 11.4 12.3 18.0 17.0 18.1 6.8 137.4 14.3 11.0 37.3 11.5 1.6 13.4 7.0 63.7 19.9 44.7 23.6 14.7 18.1 18.6 13.7 28.2 6.6 3.4 12.2 29.9 12.7 16.7 19.8 14.2 13.6 85.3 84.8 123.8 15.7 13.8 12.6 6.8 7.2 4.0 11.1 5.2 18.1 38.2 20.4 19.4 13.2 40.4 9.0 11.6 21.4 17.4 6.8 12.3 33.9 11.3 2.0 1.8 4.3 2.1 2.3 2.4 2.3 2.1 2.5 2.1 2.3 2.3 35.7 19.2 27.4 0.0 44.8 21.3 15.7 27.8 43.9 1.4 31.6 30.9 15.4 12.8 15.7 12.9 0.0 47.9 23.4 4.4 19.6 16.5 0.1 10.0 9.6 31.8 9.0 7.6 1.4 24.4 20.9 22.3 14.8 21.0 3.8 5.4 6.4 10.7 17.8 0.0 0.6 8.4 28.5 13.0 29.7 1.4 9.0 13.1 33.8 2.8 7.1 12.5 11.3 0.5 0.1 11.4 8.0 10.9 86.6 29.2 11.0 9.5 8.8 0.6 6.6 27.2 10.5 2.5 3.8 39.2 26.0 79.4 35.9 5.7 7.0 15.1 TIMM10B "FXC1, TIM10B, Tim9b" ENSG00000132286 "Translocase of inner mitochondrial membrane 10B" Q9Y5J6 11 6481501-6484681 "Predicted intracellular proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA052265 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA052265: AB_2681778" "unprognostic (1.70e-1)" "unprognostic (2.00e-1)" "unprognostic (1.96e-2)" "unprognostic (3.06e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-1)" "unprognostic (2.15e-3)" "unprognostic (1.10e-3)" "unprognostic (8.72e-2)" "unprognostic (2.86e-1)" "unprognostic (6.78e-2)" "unprognostic (1.65e-1)" "prognostic favorable (3.19e-10)" "unprognostic (9.92e-2)" "unprognostic (3.84e-1)" "unprognostic (3.61e-1)" "unprognostic (2.42e-1)" 16.5 24.0 12.1 14.2 13.3 16.9 18.1 14.4 16.8 18.5 11.4 22.6 17.0 21.6 21.9 17.0 19.4 14.8 16.1 11.5 15.6 27.5 20.3 17.7 17.2 18.7 18.2 21.6 24.5 28.9 19.2 17.3 18.4 21.9 18.6 18.2 18.2 20.1 12.4 15.5 17.6 18.8 13.3 18.4 22.7 12.9 14.6 13.9 26.6 11.3 16.8 20.6 15.8 16.9 21.7 11.8 25.6 24.4 30.6 31.1 17.8 21.2 29.4 26.3 30.1 21.7 43.5 21.8 14.8 24.7 32.7 28.5 23.8 32.3 25.4 22.0 23.3 28.6 23.8 25.0 34.3 39.6 31.1 30.9 36.0 16.8 26.4 16.9 19.7 29.1 51.5 40.2 25.3 17.2 38.7 20.9 39.5 33.8 21.1 28.8 17.2 21.4 32.8 30.4 27.2 29.5 25.0 36.1 35.9 16.7 23.1 28.4 20.7 28.4 20.2 22.9 14.8 36.3 39.9 33.3 27.4 29.2 31.0 17.2 28.9 25.8 36.5 29.8 38.5 36.0 32.6 34.8 26.7 37.9 45.2 39.6 6.5 36.0 25.2 32.9 28.6 39.6 12.1 13.3 14.4 16.8 11.5 15.6 18.7 18.2 18.4 13.3 14.6 16.9 18.7 19.2 24.1 3.9 28.5 29.1 44.8 32.2 19.4 26.2 24.1 19.3 21.0 0.0 28.2 18.4 25.0 29.5 28.0 23.3 58.7 24.4 19.8 17.1 17.7 16.9 31.0 12.6 8.6 29.7 29.5 22.6 10.2 20.6 31.1 21.1 0.0 0.0 29.3 11.8 9.9 34.5 30.5 0.0 18.9 10.9 18.3 19.1 23.2 5.6 28.7 21.8 44.3 7.5 11.7 29.3 26.9 21.1 21.6 41.7 25.0 34.0 35.8 31.2 26.3 14.9 24.1 49.0 35.2 24.0 31.1 40.2 22.5 33.3 27.2 63.7 TLR8 CD288 ENSG00000101916 "Toll like receptor 8" Q9NR97 X 12906620-12923169 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.7;lymphoid tissue: 16.8" "Group enriched" "Detected in some" 6 "Kupffer cells: 49.8;Macrophages: 21.1;monocytes: 39.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 74 "classical monocyte: 16.7;intermediate monocyte: 14.9;myeloid DC: 8.4;neutrophil: 27.6;non-classical monocyte: 15.6" "Group enriched" "Detected in many" 78 "dendritic cells: 8.4;granulocytes: 27.6;monocytes: 16.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA001608 Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA001608: AB_1080295" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (3.96e-3)" "unprognostic (4.43e-2)" "unprognostic (9.63e-2)" "unprognostic (2.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.61e-2)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.72e-2)" "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.52e-1)" "unprognostic (5.66e-2)" 3.6 0.5 0.2 16.8 0.2 5.7 0.9 0.2 0.3 0.7 0.5 1.7 0.8 0.4 0.1 0.9 0.6 2.5 0.8 0.1 0.3 0.5 2.2 10.7 6.1 1.1 0.7 0.4 0.6 0.3 0.1 4.3 0.8 0.3 1.8 0.0 0.3 0.2 0.2 0.2 1.5 3.8 0.5 13.3 0.8 0.4 0.4 1.7 0.4 1.3 1.9 3.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.0 14.9 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.0 27.6 0.0 15.6 0.0 0.0 3.8 0.2 0.2 0.2 0.3 0.1 0.3 1.1 0.7 0.8 0.5 0.4 0.9 0.0 0.0 3.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.7 5.3 0.0 0.0 0.0 0.0 49.8 5.1 0.0 0.0 21.1 0.0 0.0 39.7 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA054064: AB_2682366" "unprognostic (1.41e-1)" "unprognostic (8.76e-2)" "unprognostic (2.06e-2)" "unprognostic (2.55e-3)" "unprognostic (1.15e-1)" "unprognostic (8.37e-2)" "unprognostic (2.29e-1)" "unprognostic (8.62e-2)" "unprognostic (2.51e-2)" "unprognostic (5.40e-2)" "unprognostic (4.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.14e-2)" "unprognostic (2.92e-2)" "unprognostic (2.63e-1)" "unprognostic (3.78e-2)" "unprognostic (2.78e-2)" 32.2 38.3 58.9 23.5 62.8 28.2 33.9 57.0 74.7 36.7 51.4 31.1 24.6 40.8 43.5 23.9 34.2 29.6 47.8 62.0 70.1 32.2 58.1 28.1 30.5 54.9 58.7 55.7 30.3 40.6 35.7 31.7 58.5 32.7 24.2 32.3 34.4 35.3 44.5 27.0 26.2 32.1 55.9 29.2 29.1 28.0 61.1 29.5 45.2 55.7 31.7 32.8 28.5 58.0 20.1 48.9 25.6 46.6 71.9 53.1 31.3 25.9 42.6 30.0 33.4 26.4 55.5 32.5 34.9 35.5 50.7 45.9 40.3 33.3 23.7 31.2 88.4 48.7 39.9 45.4 47.2 38.4 55.8 44.2 66.3 18.1 37.4 42.1 42.1 41.5 40.6 47.8 47.9 40.8 28.3 40.2 39.5 90.4 16.2 33.9 32.3 51.0 61.5 52.0 34.3 31.3 35.8 37.4 54.3 43.7 35.5 49.8 33.7 31.6 32.5 21.2 28.9 45.0 71.2 35.3 26.9 47.5 26.7 36.4 40.6 81.9 41.2 41.9 46.4 30.6 33.6 31.6 29.1 44.8 44.1 41.4 69.6 52.4 32.4 24.6 38.4 41.3 58.9 62.8 57.0 74.7 62.0 70.1 54.9 58.7 58.5 55.9 61.1 58.0 52.4 25.6 28.7 22.2 55.8 66.3 58.5 142.3 32.5 47.1 42.6 45.8 35.7 35.8 67.9 42.3 33.3 73.7 51.9 23.0 19.6 61.0 8.0 28.1 38.2 48.8 27.0 30.3 41.5 42.3 64.7 53.7 23.0 44.8 25.3 37.6 60.3 56.6 32.3 69.0 55.3 23.2 91.6 42.1 36.4 10.8 73.7 39.2 26.6 37.5 44.4 60.6 56.7 29.1 45.8 27.8 20.7 62.8 41.3 66.6 32.6 39.5 47.2 46.8 72.3 40.1 67.0 89.3 84.2 25.0 55.4 91.0 55.1 21.5 27.8 40.0 TM9SF1 "HMP70, MP70" ENSG00000100926 "Transmembrane 9 superfamily member 1" O15321 14 24189149-24195687 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA059249 Supported Approved "Golgi apparatus" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA059249: AB_2683959" "unprognostic (3.27e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (9.31e-2)" "unprognostic (1.48e-1)" "unprognostic (3.84e-2)" "unprognostic (1.19e-2)" "unprognostic (4.84e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (2.62e-3)" "unprognostic (2.44e-1)" "unprognostic (4.24e-1)" "unprognostic (2.20e-1)" "unprognostic (4.18e-3)" 28.0 35.2 7.5 10.5 7.6 3.7 25.6 7.9 7.9 29.2 18.2 23.9 12.7 31.1 31.3 25.4 27.9 17.5 21.7 7.4 7.7 25.1 34.6 26.7 7.7 8.8 9.4 24.8 46.8 36.6 20.0 18.1 8.4 23.4 15.5 5.9 35.6 21.3 19.5 24.2 21.4 18.1 8.5 19.4 29.4 20.2 8.3 8.3 30.7 11.1 12.4 23.8 23.6 8.4 22.0 45.1 17.7 18.0 59.4 40.4 22.4 37.6 55.4 53.7 60.5 19.1 49.0 12.5 25.2 50.3 30.7 50.5 14.9 29.7 39.3 18.4 15.4 9.4 21.3 56.2 41.8 18.5 22.8 41.3 56.1 36.9 50.5 42.3 32.3 7.9 11.2 30.7 43.6 51.2 12.1 15.7 8.4 62.1 39.2 15.6 22.1 24.7 42.5 37.9 16.3 18.6 39.0 44.3 24.5 16.8 28.8 14.1 26.0 47.5 21.2 23.1 28.1 31.0 25.5 7.4 18.1 11.5 39.5 33.4 20.5 25.0 14.1 18.1 15.3 15.0 14.6 12.6 23.4 16.3 13.0 12.9 28.3 23.1 18.5 39.2 17.2 13.5 7.5 7.6 7.9 7.9 7.4 7.7 8.8 9.4 8.4 8.5 8.3 8.4 5.5 16.0 5.3 8.8 11.2 3.3 6.1 7.3 18.8 4.4 6.1 5.0 1.5 7.2 7.6 1.8 14.6 9.8 5.0 4.0 0.0 8.2 13.9 5.2 7.4 8.7 1.8 5.5 6.6 4.9 10.4 14.9 13.7 6.3 2.5 5.3 5.0 4.8 4.1 0.0 7.1 3.5 6.1 2.5 4.5 6.2 5.3 5.6 1.8 4.7 5.3 5.4 4.1 9.0 7.3 5.3 6.1 4.5 54.3 7.7 3.5 3.0 30.0 7.6 6.6 10.1 7.4 7.0 5.4 19.5 4.7 11.9 9.1 5.7 4.1 3.8 TM9SF2 P76 ENSG00000125304 "Transmembrane 9 superfamily member 2" Q99805 13 99446311-99564048 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005657 Supported NA NA 2100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA005657: AB_1080303" "unprognostic (9.77e-3)" "unprognostic (3.51e-2)" "unprognostic (2.85e-2)" "unprognostic (1.09e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (6.40e-4)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "unprognostic (2.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.19e-2)" "prognostic favorable (5.21e-7)" "unprognostic (6.49e-2)" "unprognostic (8.55e-2)" "unprognostic (2.20e-2)" "unprognostic (2.21e-1)" 66.6 67.2 34.4 66.7 37.4 64.6 90.6 35.9 41.4 100.2 62.5 115.8 119.4 63.6 119.0 56.1 76.6 73.6 51.0 35.8 40.3 108.4 169.4 78.6 62.1 35.9 35.1 53.2 90.2 126.8 41.5 98.2 36.6 97.8 123.7 41.9 109.6 73.2 36.3 56.6 119.3 65.7 39.8 62.4 104.1 59.6 36.9 49.7 121.2 48.3 71.3 90.0 44.4 44.9 187.3 56.7 75.8 107.8 223.2 134.8 108.2 124.1 154.5 86.6 134.8 93.1 234.7 72.1 100.0 150.1 88.4 183.1 81.1 108.7 117.8 80.8 57.8 89.6 90.9 100.2 118.0 235.8 100.0 106.2 132.4 75.1 76.8 133.2 110.4 72.8 90.7 70.0 103.0 62.8 59.1 91.9 66.3 335.7 70.0 49.3 61.0 78.7 178.9 137.3 71.7 87.5 71.7 285.6 94.8 145.5 174.0 280.5 109.1 69.6 50.7 70.5 77.8 96.6 120.8 29.0 163.8 120.0 103.0 192.4 156.4 174.9 57.7 180.5 72.8 86.9 68.4 65.3 139.6 60.1 62.8 58.4 251.3 76.0 182.1 159.6 109.6 178.1 34.4 37.4 35.9 41.4 35.8 40.3 35.9 35.1 36.6 39.8 36.9 44.9 68.9 83.3 76.3 29.0 72.5 40.9 57.3 132.8 48.9 20.6 82.9 40.5 44.0 70.1 170.7 86.5 18.8 99.3 94.5 141.1 11.7 98.6 149.2 101.0 75.6 65.4 83.0 47.9 36.6 102.7 122.8 74.6 89.2 93.9 54.5 35.2 87.4 172.9 116.0 21.9 44.4 167.9 128.1 137.6 57.2 41.8 50.1 100.7 72.9 44.0 97.4 42.7 42.2 34.2 44.8 83.4 116.7 52.3 143.1 69.0 123.5 70.8 187.7 25.3 19.7 44.1 104.1 109.7 56.3 69.8 52.1 171.4 53.2 43.2 119.4 104.0 TMBIM4 "CGI-119, GAAP, LFG4, S1R, ZPRO" ENSG00000155957 "Transmembrane BAX inhibitor motif containing 4" Q9HC24 12 66135846-66170072 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA077642 Supported "Golgi apparatus" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" "HPA077642: AB_2686849" "unprognostic (5.41e-2)" "unprognostic (1.27e-1)" "unprognostic (3.19e-1)" "unprognostic (8.14e-2)" "unprognostic (2.69e-2)" "unprognostic (5.62e-2)" "unprognostic (7.18e-3)" "unprognostic (8.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.33e-2)" "unprognostic (3.36e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.68e-2)" "unprognostic (3.75e-2)" "unprognostic (2.20e-3)" 79.7 88.6 28.0 75.3 34.3 61.5 81.4 34.0 29.7 67.3 47.6 90.5 59.5 61.0 68.6 62.6 65.8 70.1 70.8 27.1 35.6 94.0 109.6 76.7 74.5 38.5 32.1 56.7 103.5 104.7 40.1 74.2 39.1 72.8 70.2 39.7 89.3 73.7 46.7 52.2 69.8 58.5 34.7 74.4 93.3 85.1 31.0 63.1 97.9 61.5 56.0 80.0 42.9 41.5 49.1 62.4 39.7 72.8 131.4 122.7 41.9 74.4 129.1 56.7 45.8 32.8 78.7 45.6 86.3 105.2 42.6 78.9 20.1 65.7 36.6 74.5 27.3 87.7 30.0 38.6 66.6 106.9 109.2 86.9 92.8 27.7 31.1 79.0 87.2 51.8 65.9 160.3 94.3 79.5 41.1 37.5 47.4 76.1 63.3 21.5 26.5 50.8 126.8 80.3 20.1 47.6 84.5 154.5 102.3 34.2 146.3 146.7 106.0 69.1 25.9 50.5 44.8 82.7 48.5 32.2 94.8 103.7 84.1 420.7 372.7 371.6 136.0 381.4 137.9 205.9 139.7 139.4 256.2 196.6 157.9 139.1 662.3 135.3 434.3 171.7 159.8 483.9 28.0 34.3 34.0 29.7 27.1 35.6 38.5 32.1 39.1 34.7 31.0 41.5 232.8 150.6 147.2 34.0 131.3 0.0 64.1 0.0 84.2 47.8 202.2 152.1 37.0 0.0 66.2 244.6 45.9 137.0 128.2 191.4 103.7 213.8 330.6 116.2 96.4 114.5 74.7 32.0 15.8 338.1 116.9 140.7 85.1 105.8 179.0 72.7 0.0 0.0 210.7 45.4 25.2 172.4 0.0 0.0 0.0 143.8 104.4 193.2 0.0 62.8 205.5 114.1 123.6 42.7 77.0 202.9 176.9 91.0 126.8 87.9 128.9 214.5 99.1 65.9 59.2 67.8 75.7 391.0 40.8 112.5 0.0 130.8 99.3 142.7 182.2 62.8 TMBIM6 "BAXI1, BI-1, TEGT" ENSG00000139644 "Transmembrane BAX inhibitor motif containing 6" P55061 12 49707725-49764934 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1803.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 2394.6;Late spermatids: 2375.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017378 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "HPA017378: AB_2669604" "prognostic unfavorable (3.54e-4)" "unprognostic (6.25e-2)" "unprognostic (1.90e-2)" "unprognostic (6.52e-2)" "unprognostic (8.46e-3)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.37e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-2)" "unprognostic (6.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.80e-1)" "prognostic favorable (1.00e-5)" "unprognostic (1.95e-1)" "unprognostic (9.27e-2)" "unprognostic (1.28e-1)" "unprognostic (1.54e-2)" 333.4 364.8 332.1 276.3 361.6 315.4 416.8 347.5 376.4 413.7 528.2 493.6 475.8 252.3 640.9 406.3 431.1 360.3 215.5 301.1 358.3 1144.5 1803.2 423.3 292.3 374.4 346.9 281.2 574.2 577.5 133.7 303.1 378.7 383.2 494.4 305.0 479.8 409.3 232.1 231.4 536.1 294.7 351.9 267.8 549.8 247.9 366.9 313.0 596.4 232.3 332.3 406.2 216.5 395.2 609.6 516.6 413.3 381.1 1169.3 645.1 513.6 450.2 854.0 572.0 519.7 837.6 1703.8 380.3 746.9 882.6 598.6 648.1 363.7 659.4 619.2 551.7 390.3 606.2 367.8 414.0 707.7 701.9 959.4 657.5 1511.3 640.9 925.8 809.3 481.6 461.0 556.2 1526.5 662.5 589.5 362.1 424.2 432.1 730.6 392.2 302.8 413.0 651.0 871.5 909.9 319.0 208.7 603.5 786.1 511.2 530.7 989.4 731.6 456.8 522.6 393.9 355.8 396.9 654.2 717.8 326.8 730.9 324.3 260.8 896.4 749.8 795.5 559.9 721.8 587.8 403.6 501.1 558.5 585.5 356.6 438.9 501.8 1242.0 463.8 769.5 587.0 544.8 1813.1 332.1 361.6 347.5 376.4 301.1 358.3 374.4 346.9 378.7 351.9 366.9 395.2 428.2 477.5 455.5 80.6 314.2 261.0 535.0 836.9 222.5 245.8 526.8 337.6 221.0 571.9 766.5 544.4 114.7 406.9 366.7 995.8 131.0 927.3 1504.8 340.5 240.0 321.9 294.9 232.7 43.9 816.9 913.0 336.0 325.7 501.9 257.7 194.5 358.7 2394.6 618.9 180.0 57.3 612.6 598.1 570.6 292.8 2375.1 288.6 458.2 247.3 58.1 540.3 467.7 285.3 94.5 115.5 846.7 651.3 287.3 589.8 550.0 1585.8 809.6 874.1 154.8 170.9 191.7 361.1 458.1 214.7 272.7 235.0 891.0 315.9 372.8 552.2 654.4 TMCO1 "HP10122, TMCC4" ENSG00000143183 "Transmembrane and coiled-coil domains 1" Q9UM00 1 165724293-165827755 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, Glaucoma, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054768, HPA078775" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "HPA054768: AB_2682597, HPA078775: " "unprognostic (1.22e-2)" "unprognostic (3.28e-3)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (5.17e-7)" "prognostic unfavorable (3.21e-4)" "unprognostic (5.92e-2)" "unprognostic (4.16e-2)" "unprognostic (7.95e-3)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.85e-1)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (9.80e-2)" 67.5 92.5 46.4 51.6 50.2 48.4 91.1 53.8 63.5 74.0 72.2 127.0 115.7 55.9 111.5 58.5 65.9 80.1 56.4 46.4 55.6 110.3 162.5 55.0 62.4 54.1 55.5 59.5 73.5 143.6 33.8 57.4 55.0 79.6 128.7 74.3 77.8 69.9 48.7 39.3 108.9 61.4 56.6 46.5 80.7 75.4 49.8 89.3 103.8 48.0 70.8 97.7 29.1 60.6 158.4 172.1 132.2 77.9 243.9 120.7 126.9 259.4 191.7 156.0 162.1 249.9 229.2 99.1 267.4 195.9 67.1 214.7 171.8 140.3 175.1 252.0 164.2 121.1 180.3 158.7 195.1 216.6 154.1 159.0 173.9 179.5 142.6 148.4 117.1 122.6 329.7 186.0 227.3 123.1 172.1 160.6 169.4 527.6 197.3 125.0 143.4 256.1 204.7 198.4 133.5 235.4 201.3 209.2 170.9 195.0 277.1 275.7 121.5 138.9 116.5 123.8 248.3 357.4 521.1 346.5 111.4 139.7 187.4 213.3 172.2 172.9 159.7 169.4 170.4 151.8 168.7 173.1 135.5 132.6 134.3 156.5 132.1 156.6 201.7 243.8 207.1 290.3 46.4 50.2 53.8 63.5 46.4 55.6 54.1 55.5 55.0 56.6 49.8 60.6 124.0 96.1 70.7 23.8 95.6 84.8 89.8 264.5 75.1 79.1 142.9 135.9 62.6 224.4 181.1 213.3 68.8 136.1 138.9 371.5 43.0 202.3 82.2 131.4 147.9 92.7 88.6 75.5 20.7 191.7 148.4 113.1 64.2 154.7 76.5 71.9 106.7 326.0 140.9 75.7 24.9 137.0 227.9 106.4 76.0 151.6 123.6 92.7 99.6 16.9 78.9 236.7 152.4 25.6 23.3 227.0 215.7 129.4 153.5 73.6 290.0 151.5 175.2 75.9 124.9 67.7 101.7 232.1 87.7 89.4 92.9 111.4 109.2 117.6 143.6 94.5 TMED1 "Il1rl1l, IL1RL1LG, MGC1270, p24g1, p24gamma1, ST2L" ENSG00000099203 "Transmembrane p24 trafficking protein 1" Q13445 19 10832067-10836318 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018507 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 38: EFO-21 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "HPA018507: AB_1858063" "unprognostic (6.98e-2)" "unprognostic (3.42e-1)" "unprognostic (3.03e-3)" "unprognostic (1.28e-1)" "unprognostic (8.65e-2)" "unprognostic (2.27e-1)" "unprognostic (1.98e-2)" "unprognostic (4.20e-2)" "unprognostic (9.86e-2)" "unprognostic (7.27e-2)" "unprognostic (9.52e-2)" "unprognostic (4.93e-2)" "prognostic favorable (8.66e-5)" "unprognostic (9.49e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-2)" "unprognostic (2.45e-2)" 23.6 31.2 13.4 15.4 15.3 21.6 25.1 15.6 17.3 30.0 24.9 19.5 18.9 25.0 16.3 19.9 24.8 18.8 42.3 13.0 16.9 37.8 51.9 19.6 14.3 16.6 15.1 34.4 34.5 24.4 35.9 21.4 15.5 26.5 8.1 4.4 24.2 14.8 64.4 19.1 17.4 10.6 15.2 22.3 26.2 20.2 14.5 10.2 28.7 34.9 7.0 22.3 21.0 17.4 40.4 63.3 26.7 43.6 26.2 28.5 27.8 63.3 53.0 59.0 82.3 59.2 57.2 29.1 146.5 46.0 30.8 32.2 18.8 33.4 23.6 44.2 38.5 41.5 49.8 48.5 35.4 35.2 91.4 42.2 35.1 34.9 24.9 25.8 37.4 22.3 30.3 80.6 25.3 63.9 25.4 38.0 41.3 23.6 60.5 27.8 22.9 44.6 35.0 33.3 29.5 29.0 37.6 37.0 33.9 11.2 43.8 38.5 41.5 75.1 34.4 80.3 71.6 48.9 56.6 27.8 58.1 63.5 41.6 12.3 94.6 44.3 59.3 94.0 40.9 50.9 39.9 48.6 81.1 42.2 36.6 40.5 35.7 122.8 103.0 59.9 38.9 66.0 13.4 15.3 15.6 17.3 13.0 16.9 16.6 15.1 15.5 15.2 14.5 17.4 20.2 9.6 15.3 4.6 16.5 18.5 24.4 53.9 12.0 10.2 31.8 32.0 0.2 41.5 33.0 53.3 8.4 111.5 24.5 22.7 41.1 54.4 5.5 30.9 26.7 26.4 23.5 30.7 1.0 44.2 94.0 38.1 15.8 21.7 27.3 43.7 24.3 43.9 52.5 5.0 1.2 21.1 46.8 20.2 16.6 6.3 22.4 20.0 42.7 1.0 25.0 40.3 28.8 4.0 3.2 41.7 35.5 20.3 24.4 35.4 37.7 57.4 42.9 18.0 32.9 28.9 27.1 21.7 30.9 14.8 17.5 146.3 15.1 62.3 28.8 23.3 TMED10 "p23, P24(DELTA), p24d1, p24delta1, TMP21" ENSG00000170348 "Transmembrane p24 trafficking protein 10" P49755 14 75131469-75176612 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034442, CAB037251, HPA047139, HPA050539" Enhanced Supported "Golgi apparatus" NA NA 220000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "CAB034442: AB_2204336, CAB037251: AB_1841216, HPA047139: AB_2679951, HPA050539: AB_2681163" "unprognostic (2.00e-1)" "unprognostic (1.73e-2)" "unprognostic (2.02e-1)" "unprognostic (2.51e-3)" "unprognostic (4.06e-1)" "unprognostic (1.17e-3)" "unprognostic (5.88e-2)" "unprognostic (1.21e-1)" "unprognostic (3.68e-2)" "unprognostic (6.46e-3)" "unprognostic (1.01e-2)" "unprognostic (1.27e-2)" "unprognostic (1.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (2.06e-2)" 68.0 70.3 51.8 55.2 55.8 18.0 93.2 52.6 60.7 137.9 61.2 77.0 62.3 92.6 133.1 59.9 100.6 69.2 82.3 49.5 66.1 62.7 126.9 68.0 61.0 65.8 54.3 99.7 131.9 91.4 53.6 76.3 63.2 91.0 82.3 48.8 130.7 85.9 73.7 56.0 58.8 78.9 57.5 54.6 78.3 40.0 58.2 73.7 146.0 61.0 65.9 66.9 59.7 69.6 93.3 52.2 85.5 142.5 197.5 183.7 110.9 96.5 159.5 99.5 111.2 51.8 161.2 82.5 80.6 167.5 56.8 90.8 80.4 140.6 160.5 43.7 36.2 50.5 31.1 79.2 167.1 101.7 50.2 135.1 221.5 77.0 220.1 196.0 176.9 91.7 44.6 177.8 145.0 104.6 71.0 80.7 51.9 145.2 55.8 70.6 55.3 116.6 119.7 94.8 82.9 87.1 89.0 147.0 175.9 81.0 138.3 163.3 122.3 97.0 62.9 65.9 50.7 98.9 99.3 91.3 177.0 88.3 95.8 107.4 46.4 28.9 60.8 39.4 93.8 39.7 58.7 59.3 62.9 30.3 51.9 55.9 20.4 101.8 42.6 70.9 38.2 91.4 51.8 55.8 52.6 60.7 49.5 66.1 65.8 54.3 63.2 57.5 58.2 69.6 80.8 64.1 106.3 32.0 141.8 114.2 180.4 488.1 107.0 55.6 182.5 130.6 155.3 187.3 279.9 200.5 27.1 181.0 186.7 186.2 62.6 319.1 14.5 147.7 177.5 107.3 140.7 75.5 26.9 385.7 609.9 164.4 145.8 172.0 100.1 170.9 123.1 339.7 255.0 77.4 30.0 276.2 272.6 159.4 166.3 31.5 179.3 151.6 297.1 38.4 129.5 137.9 130.7 50.8 84.2 225.8 148.9 209.9 538.8 218.7 120.3 138.9 304.8 63.1 78.9 112.7 132.2 317.7 116.5 151.7 135.1 309.2 122.1 145.8 161.9 207.7 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMED3 "C15orf22, p24B, p24g4, p24gamma4" ENSG00000166557 "Transmembrane p24 trafficking protein 3" Q9Y3Q3 15 79311112-79427432 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 409.4" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049314, HPA076949" Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "HPA049314: AB_2680708, HPA076949: AB_2686820" "prognostic unfavorable (7.71e-4)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (8.86e-3)" "unprognostic (1.41e-1)" "unprognostic (2.03e-3)" "unprognostic (2.42e-2)" "unprognostic (2.49e-1)" "unprognostic (4.85e-1)" "unprognostic (9.06e-2)" "unprognostic (8.09e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.16e-1)" "unprognostic (2.88e-1)" "unprognostic (2.50e-1)" "unprognostic (1.52e-1)" 25.9 26.2 19.6 23.1 19.2 37.0 66.4 21.5 20.5 56.6 30.6 49.9 25.4 38.3 138.7 132.3 38.7 37.8 41.9 20.8 31.9 34.7 12.4 30.9 26.0 22.4 22.0 30.9 246.7 54.9 89.6 42.4 26.5 60.0 55.4 11.3 409.4 54.6 4.6 106.8 26.6 37.3 21.6 32.4 73.1 35.0 22.6 23.1 76.3 7.2 37.8 48.7 75.1 25.1 68.1 169.0 31.9 63.6 220.3 167.5 69.0 153.0 206.7 103.3 126.9 141.4 123.3 31.5 117.3 236.0 135.9 124.5 95.7 98.5 53.0 62.7 145.6 104.5 143.0 110.3 131.5 112.2 200.4 126.5 144.4 59.6 86.9 123.5 120.8 105.9 47.1 0.6 101.4 144.3 32.1 106.0 45.7 251.6 92.2 39.1 47.4 158.9 94.2 51.4 99.4 48.8 80.6 162.1 159.3 103.5 141.5 81.7 98.5 85.2 75.7 2.2 111.4 61.7 78.8 44.1 109.8 180.7 103.1 74.9 69.8 95.1 58.1 85.3 62.7 75.5 57.2 63.9 106.7 63.6 71.4 69.1 6.0 61.4 95.7 109.1 73.1 92.2 19.6 19.2 21.5 20.5 20.8 31.9 22.4 22.0 26.5 21.6 22.6 25.1 9.9 28.9 43.6 6.8 41.2 95.8 109.4 125.6 64.9 14.9 153.8 132.8 16.9 55.8 108.5 57.0 8.4 167.8 40.7 67.7 23.5 143.4 48.9 31.6 39.6 31.7 83.9 33.7 10.0 250.5 294.5 68.1 54.6 70.4 47.0 44.0 65.7 6.4 100.5 13.5 10.2 219.3 87.5 52.7 54.4 118.6 49.7 49.2 85.4 9.4 60.0 38.0 44.3 17.1 12.9 173.3 79.9 27.4 71.1 165.2 43.9 28.9 37.7 17.0 19.7 25.6 57.0 51.1 60.3 104.7 121.8 172.4 30.4 64.6 126.4 200.1 TMED4 "HNLF, p24a3, p24alpha3" ENSG00000158604 "Transmembrane p24 trafficking protein 4" Q7Z7H5 7 44577894-44582287 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014650 Approved "Intracellular and membrane" NA NA 24000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA014650: AB_1858066" "unprognostic (7.34e-2)" "unprognostic (1.68e-3)" "unprognostic (1.46e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (2.09e-3)" "unprognostic (4.50e-3)" "unprognostic (2.54e-2)" "unprognostic (3.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.42e-3)" "unprognostic (4.65e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.21e-1)" "unprognostic (6.12e-2)" "unprognostic (4.11e-1)" "unprognostic (6.61e-2)" 35.2 51.7 40.5 32.2 48.3 49.5 42.9 44.8 43.2 48.9 53.2 46.5 87.9 51.2 78.6 37.3 53.9 37.2 65.0 40.9 48.5 88.3 49.0 42.1 37.1 47.8 45.3 72.0 73.0 139.4 68.3 61.9 47.9 57.5 48.1 92.0 67.3 65.1 61.5 40.5 92.8 44.3 44.1 38.5 51.7 31.4 44.0 38.3 114.0 41.6 38.1 42.3 40.5 56.7 47.2 57.0 80.0 90.8 70.7 41.8 68.6 55.7 68.8 56.4 70.1 62.2 114.1 44.5 90.9 60.0 120.8 74.9 42.5 46.7 67.9 59.3 69.0 39.5 100.4 59.6 63.7 63.8 72.8 54.5 69.7 59.7 48.4 103.8 50.7 68.9 62.8 96.4 67.6 42.4 61.8 86.2 51.5 73.1 57.5 52.6 37.2 87.4 81.7 76.6 64.0 91.3 59.4 132.7 64.4 90.7 103.8 64.1 47.3 41.3 61.0 47.8 88.1 143.9 140.0 53.6 84.6 67.5 148.8 95.3 60.2 87.2 85.3 63.3 103.4 67.4 85.0 82.2 55.1 54.5 69.5 77.8 58.5 82.8 71.3 120.7 79.2 56.6 40.5 48.3 44.8 43.2 40.9 48.5 47.8 45.3 47.9 44.1 44.0 56.7 41.4 118.6 74.0 11.8 70.3 56.2 53.5 61.0 44.9 150.5 83.2 77.2 69.8 62.9 66.0 154.5 75.0 176.0 83.5 79.7 41.1 79.4 54.9 79.3 61.7 36.8 62.9 49.2 25.5 60.6 57.4 75.2 45.9 92.9 41.1 89.9 36.4 55.5 70.7 112.7 30.2 75.0 63.1 45.9 55.0 100.4 78.3 50.4 40.9 12.2 56.9 115.7 41.2 25.1 31.0 79.0 78.6 81.3 142.7 75.6 267.7 140.9 69.4 135.9 59.2 87.1 65.8 51.8 60.8 47.0 56.8 159.9 74.1 60.3 79.6 76.3 TMED7 "CGI-109, FLJ90481, p24g3, p24gamma3" ENSG00000134970 "Transmembrane p24 trafficking protein 7" Q9Y3B3 5 115613210-115632992 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008960, CAB025883" Supported NA NA 13000 "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "CAB025883: , HPA008960: AB_1080280" "unprognostic (1.40e-1)" "unprognostic (8.42e-2)" "unprognostic (1.45e-2)" "unprognostic (1.22e-1)" "unprognostic (2.04e-1)" "unprognostic (4.35e-2)" "unprognostic (1.27e-1)" "unprognostic (2.26e-3)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (6.15e-3)" "unprognostic (4.10e-2)" "unprognostic (6.82e-2)" "unprognostic (4.95e-2)" "unprognostic (3.06e-1)" "unprognostic (4.79e-2)" "unprognostic (1.22e-1)" 35.0 41.2 23.1 29.5 31.9 31.8 37.8 31.2 32.7 50.5 37.8 42.1 36.9 41.2 70.2 32.4 38.6 33.5 43.5 21.9 24.6 54.2 80.2 30.5 23.4 39.8 27.2 31.0 35.2 53.6 28.0 43.8 28.1 48.7 42.3 19.2 43.4 44.3 22.0 18.9 38.3 45.0 33.3 25.9 41.5 18.9 28.5 19.5 79.8 24.9 24.1 37.6 22.6 44.8 63.6 42.4 43.8 54.7 112.3 84.4 68.1 109.8 116.4 79.7 129.8 36.3 110.1 33.1 105.7 115.1 99.5 49.6 41.3 128.0 125.7 76.0 34.4 30.5 39.2 76.8 119.8 31.9 59.0 78.2 60.5 76.1 95.8 100.4 78.5 22.3 29.6 44.5 87.1 30.1 24.0 28.5 30.8 37.7 35.5 25.9 65.1 63.8 98.6 44.6 33.3 39.8 90.0 52.3 68.1 41.7 63.0 41.8 80.1 109.0 46.3 79.2 66.3 29.3 24.0 33.5 88.7 52.2 61.8 25.5 23.8 20.2 14.9 23.1 15.3 10.4 11.5 13.3 19.3 9.1 11.1 12.0 16.3 14.2 18.5 13.3 11.5 20.7 23.1 31.9 31.2 32.7 21.9 24.6 39.8 27.2 28.1 33.3 28.5 44.8 37.8 38.5 29.8 0.0 26.9 45.6 30.1 35.3 15.4 31.5 47.4 21.5 42.4 61.5 29.3 46.0 10.4 44.2 30.6 63.8 13.7 37.4 28.7 34.5 48.9 30.6 87.3 9.1 0.0 28.3 103.6 51.8 34.1 45.6 10.1 20.4 44.3 114.2 50.1 30.3 0.0 85.8 24.4 51.6 55.5 20.1 46.9 38.4 51.6 0.0 36.8 52.6 19.6 0.0 0.0 37.4 39.9 53.4 13.9 60.5 50.0 42.2 36.9 25.8 39.5 42.9 43.1 39.2 18.0 25.3 44.0 82.8 23.6 33.9 46.9 55.6 TMEM106B "FLJ11273, MGC33727" ENSG00000106460 "Transmembrane protein 106B" Q9NUM4 7 12211270-12243367 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Amyotrophic lateral sclerosis, Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058342 Approved Supported Endosomes,Lysosomes NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Endosomes, Lysosomes" "HPA058342: AB_2683684" "unprognostic (5.29e-2)" "unprognostic (2.34e-2)" "unprognostic (4.20e-2)" "unprognostic (6.20e-2)" "unprognostic (2.73e-1)" "unprognostic (1.87e-2)" "unprognostic (3.50e-2)" "unprognostic (5.89e-2)" "unprognostic (4.44e-2)" "unprognostic (1.30e-1)" "unprognostic (3.01e-3)" "unprognostic (2.09e-2)" "unprognostic (1.75e-3)" "unprognostic (5.52e-2)" "unprognostic (3.06e-2)" "unprognostic (2.16e-2)" "unprognostic (1.70e-1)" 9.9 26.1 6.0 7.1 8.5 7.2 10.9 10.7 9.1 13.1 7.6 12.6 8.6 14.7 12.2 10.3 11.2 9.1 11.4 6.3 7.0 17.8 18.8 7.7 7.9 7.4 7.4 12.0 10.1 12.7 9.9 14.0 8.1 14.6 11.5 14.6 13.1 13.9 14.7 9.0 10.2 12.7 10.5 8.4 8.9 7.0 7.4 6.7 16.0 12.2 6.8 10.7 10.2 14.5 13.9 26.3 14.8 24.2 26.3 21.3 11.5 19.7 33.3 12.6 12.7 8.6 42.1 3.7 21.2 23.5 30.0 14.6 11.9 12.5 10.5 7.2 11.5 5.5 14.5 8.3 20.8 20.5 8.6 22.1 14.1 9.9 19.2 57.5 16.0 10.2 16.1 11.1 14.9 4.4 3.9 8.6 17.4 17.5 13.9 11.1 10.9 10.1 23.5 12.4 15.4 21.4 18.8 15.4 16.7 20.0 13.9 10.0 18.9 14.0 20.3 14.1 16.2 15.0 28.6 5.9 19.6 6.7 35.2 11.6 4.3 5.3 9.1 5.2 12.8 6.1 10.6 10.6 2.9 7.8 17.3 13.2 2.8 14.4 7.9 0.9 10.3 6.8 6.0 8.5 10.7 9.1 6.3 7.0 7.4 7.4 8.1 10.5 7.4 14.5 45.0 73.7 40.3 41.1 34.3 36.8 42.6 38.5 62.6 55.0 46.0 30.4 46.0 38.6 49.3 66.2 45.9 54.0 18.9 53.6 17.6 115.4 5.0 29.2 56.3 34.6 57.6 24.4 60.1 58.7 36.0 65.8 36.7 37.8 14.5 53.8 41.7 85.1 33.3 65.6 78.6 37.9 57.0 29.2 23.9 4.3 49.0 23.9 37.4 28.1 19.1 95.2 39.1 66.9 82.3 75.3 53.4 60.9 39.9 85.0 57.1 67.7 47.4 51.8 32.9 49.5 41.6 40.1 31.6 56.4 43.3 135.6 41.1 70.7 47.2 81.9 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 988.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" 56.0 80.2 53.0 120.2 60.3 225.1 153.3 56.7 68.2 114.9 67.0 120.0 63.5 174.7 47.8 100.1 91.7 99.6 71.2 48.0 61.0 93.2 393.7 119.2 196.4 71.2 68.6 86.8 82.5 70.7 15.8 98.5 65.1 105.2 97.1 9.2 224.0 104.1 20.4 95.6 78.8 130.6 61.3 111.2 125.5 73.3 61.5 238.6 312.3 49.7 142.9 146.8 70.7 89.8 220.5 195.8 186.9 174.8 233.5 185.6 135.8 169.7 352.0 324.4 358.1 247.9 988.1 370.2 423.9 387.9 234.5 228.3 212.3 272.9 339.4 228.4 82.5 192.0 67.8 352.3 207.5 404.1 137.4 219.1 280.7 240.1 352.3 433.9 361.8 187.8 134.3 0.9 257.7 71.8 353.0 135.4 115.8 340.3 181.1 214.7 532.0 359.3 291.3 207.9 90.7 110.5 201.8 267.6 109.9 197.2 161.3 154.0 451.9 211.3 249.4 190.5 126.6 139.4 84.3 366.6 62.0 432.7 143.2 159.7 113.3 207.0 102.6 121.8 155.3 70.1 158.8 123.8 126.1 95.3 208.6 181.7 72.4 223.9 111.0 33.7 183.8 248.7 53.0 60.3 56.7 68.2 48.0 61.0 71.2 68.6 65.1 61.3 61.5 89.8 93.3 125.0 78.1 33.0 179.3 160.3 257.1 307.3 157.6 0.7 144.9 118.4 53.9 143.0 202.8 163.7 0.0 45.8 91.8 48.2 80.3 153.7 41.3 141.1 47.6 140.0 90.5 68.3 1.0 118.8 41.1 82.2 88.2 161.4 58.9 126.6 271.3 317.6 107.1 1.7 2.2 163.1 160.7 249.6 419.9 23.6 94.1 189.8 161.9 63.7 229.4 4.7 83.4 25.6 114.0 127.8 55.1 93.3 117.8 324.2 31.0 52.9 257.0 1.1 65.7 181.9 80.2 23.1 74.9 146.3 177.2 30.4 164.8 109.4 146.3 270.2 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM144 FLJ11155 ENSG00000164124 "Transmembrane protein 144" Q7Z5S9 4 158201604-158255416 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 418.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 994.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.1;plasmacytoid DC: 2.2" "Group enriched" "Detected in many" 10 "dendritic cells: 2.2;monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 36.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063554 Approved Mitochondria NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA063554: AB_2685039" "unprognostic (1.26e-2)" "unprognostic (7.05e-2)" "unprognostic (2.06e-2)" "prognostic favorable (2.89e-4)" "unprognostic (2.90e-1)" "unprognostic (1.71e-5)" "unprognostic (8.27e-2)" "unprognostic (3.32e-1)" "unprognostic (2.21e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (9.34e-2)" "unprognostic (1.13e-2)" "unprognostic (1.35e-1)" "unprognostic (9.26e-2)" "unprognostic (3.88e-2)" "unprognostic (4.05e-2)" 8.6 12.9 91.0 3.6 235.8 3.1 15.4 164.3 134.4 7.6 15.3 14.4 29.4 6.1 15.6 5.4 6.8 12.5 14.9 101.1 122.5 3.8 3.2 6.3 2.3 204.2 158.6 13.5 7.4 4.6 1.3 6.5 201.8 9.0 15.9 0.6 5.9 10.9 2.8 3.4 20.7 7.1 133.8 4.0 11.2 27.0 163.9 1.9 16.9 2.6 1.6 6.6 2.6 418.0 4.7 12.1 0.2 2.6 8.6 11.8 36.5 1.9 3.9 1.7 2.8 15.1 17.8 0.0 2.8 0.6 10.0 2.2 5.1 16.7 2.4 0.0 5.5 8.5 3.0 13.5 2.8 10.7 2.3 8.9 20.0 7.0 3.0 0.5 9.7 1.7 5.5 0.2 12.8 5.1 0.0 0.0 3.2 15.1 2.9 0.0 0.0 0.4 4.2 12.3 1.9 0.0 0.5 19.6 4.2 7.1 12.6 2.4 1.8 3.9 2.7 0.7 2.1 0.0 1.1 0.9 5.4 1.4 3.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.1 0.3 2.2 0.0 0.3 91.0 235.8 164.3 134.4 101.1 122.5 204.2 158.6 201.8 133.8 163.9 418.0 2.9 9.6 9.1 53.2 0.3 3.1 7.7 5.2 2.8 0.9 12.4 10.7 12.7 12.8 8.4 0.0 0.0 13.7 1.5 36.6 0.0 15.4 231.8 14.5 8.6 4.8 4.9 3.0 10.9 13.3 6.5 4.4 14.8 24.5 4.5 14.6 4.6 1.2 29.0 0.0 12.5 21.4 8.2 20.8 5.0 98.2 10.5 12.9 3.6 12.2 10.6 1.3 0.0 5.5 994.4 9.0 18.9 9.1 0.2 3.5 44.1 6.4 8.8 0.2 0.0 8.5 2.6 3.0 2.2 5.8 5.1 8.8 0.9 6.8 18.6 6.4 TMEM14B MGC1223 ENSG00000137210 "Transmembrane protein 14B" Q9NUH8 6 10747759-10852753 "Predicted membrane proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.45e-3)" "unprognostic (6.80e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.51e-4)" "unprognostic (5.45e-1)" "unprognostic (2.58e-3)" "prognostic unfavorable (9.35e-5)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "prognostic favorable (7.41e-4)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (8.24e-2)" "unprognostic (4.77e-2)" "unprognostic (4.83e-2)" "unprognostic (1.92e-1)" "unprognostic (1.07e-1)" 78.4 101.1 58.2 45.0 60.6 186.3 74.8 62.9 81.2 51.8 77.6 60.3 53.7 46.5 78.0 47.4 72.0 48.7 132.8 59.8 60.6 81.9 91.0 45.2 70.9 61.1 59.3 50.1 64.3 77.3 40.3 41.5 60.5 65.5 58.8 151.6 86.1 44.1 146.5 46.0 59.2 42.6 61.0 42.2 64.4 27.5 60.4 78.6 128.1 141.5 57.5 52.2 41.4 63.6 376.2 155.9 72.9 106.7 80.0 102.8 106.4 77.9 136.6 163.8 193.2 153.8 171.8 130.8 187.1 93.1 375.9 81.8 65.5 135.1 253.4 89.3 89.6 107.9 123.1 235.2 120.0 163.2 102.1 83.6 76.7 174.6 174.9 92.3 91.6 120.1 267.2 54.1 135.0 134.7 144.4 182.0 110.1 198.6 118.9 120.1 97.1 304.9 198.7 91.7 117.9 88.0 95.7 188.6 251.3 139.0 132.3 145.0 91.7 120.0 150.0 82.3 268.6 128.4 289.4 175.7 98.5 92.4 190.1 178.1 112.1 161.2 86.1 109.8 121.5 121.7 120.7 100.1 136.3 114.7 130.3 111.5 64.4 117.0 122.3 168.6 141.0 154.9 58.2 60.6 62.9 81.2 59.8 60.6 61.1 59.3 60.5 61.0 60.4 63.6 103.2 80.1 77.2 21.5 95.4 82.0 92.1 169.9 90.5 85.5 157.9 206.8 141.4 144.4 113.8 88.3 60.5 177.1 89.7 94.1 365.9 183.3 18.9 190.4 73.2 83.5 80.5 399.9 19.9 220.9 183.0 97.0 68.3 101.9 82.4 90.2 70.6 156.3 210.0 107.7 21.2 143.2 130.2 121.0 132.6 53.5 96.3 110.1 120.9 9.4 265.8 239.0 52.5 17.1 18.1 261.3 102.5 75.2 102.5 145.8 142.0 309.5 247.6 196.1 26.3 95.6 92.8 46.5 129.9 103.9 100.7 105.9 99.4 133.3 164.3 109.0 TMEM167B "AD-020, C1orf119, FLJ90710" ENSG00000215717 "Transmembrane protein 167B" Q9NRX6 1 109090764-109096934 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (7.89e-2)" "unprognostic (3.28e-1)" "unprognostic (4.96e-2)" "prognostic favorable (8.86e-4)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-3)" "unprognostic (2.37e-2)" "unprognostic (1.28e-1)" "unprognostic (7.20e-2)" "unprognostic (1.74e-1)" "unprognostic (3.01e-1)" "unprognostic (3.21e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (2.25e-1)" 31.7 35.5 29.9 24.2 30.3 53.7 33.1 30.0 34.4 32.4 29.6 27.7 23.2 30.9 31.6 24.0 25.4 25.6 35.9 30.1 30.5 33.3 33.0 28.4 26.2 29.1 30.2 29.7 25.7 45.1 15.9 33.8 29.6 36.9 29.8 31.3 30.3 27.9 21.3 28.9 23.7 30.6 31.3 28.3 32.4 23.4 30.9 25.1 41.7 25.9 27.7 27.2 16.3 33.0 36.1 6.5 23.4 32.3 47.8 47.0 20.9 54.2 49.7 30.0 27.8 13.7 13.4 24.0 30.1 55.9 17.8 17.4 15.1 24.1 43.0 37.4 11.4 22.4 8.7 18.8 53.6 43.6 36.6 38.8 64.7 27.9 46.7 40.8 26.5 30.8 28.5 33.9 33.0 22.2 33.0 28.1 17.7 31.0 33.1 20.5 37.1 19.0 38.6 22.5 16.6 17.0 26.2 38.0 53.0 20.8 23.7 32.0 25.2 30.6 30.8 67.0 26.6 34.0 20.6 23.7 51.7 44.7 65.0 38.1 20.7 35.4 13.3 23.8 19.1 14.4 17.6 17.0 19.1 13.5 17.8 17.8 45.4 17.5 30.8 11.7 17.9 19.9 29.9 30.3 30.0 34.4 30.1 30.5 29.1 30.2 29.6 31.3 30.9 33.0 29.6 32.1 31.4 10.7 30.1 30.5 29.4 25.7 16.5 30.1 28.2 17.9 34.0 22.8 28.6 18.4 12.5 42.1 38.7 20.0 19.6 26.7 19.1 16.2 25.2 30.7 20.9 25.9 11.5 30.1 44.3 32.3 23.0 27.1 32.3 21.7 27.8 21.7 39.1 25.2 12.5 25.2 24.4 36.8 42.8 17.0 28.9 38.8 26.6 6.5 56.3 36.0 24.7 12.5 16.4 29.3 19.7 25.2 16.8 39.8 25.9 29.6 19.7 30.1 0.0 21.7 26.8 28.9 28.2 26.0 35.7 63.1 32.9 20.4 19.1 51.5 TMEM171 PRP2 ENSG00000157111 "Transmembrane protein 171" Q8WVE6 5 73120569-73131809 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 35.6;kidney: 10.8;lymphoid tissue: 14.3;stomach 1: 25.4;thyroid gland: 31.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.6;Distal enterocytes: 106.0;Gastric mucus-secreting cells: 29.6;Ionocytes: 40.7;Paneth cells: 63.4;Proximal enterocytes: 41.9;Undifferentiated cells: 51.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "MAIT T-cell: 24.1;memory CD8 T-cell: 8.2" "Lineage enriched" "Detected in single" 89 "T-cells: 24.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 35.0;LHCN-M2: 66.1;RPTEC TERT1: 51.5;WM-115: 177.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 3.7" HPA042308 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA042308: AB_10796901" "unprognostic (7.34e-2)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (7.74e-3)" "unprognostic (2.81e-5)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.44e-3)" "unprognostic (1.77e-1)" "unprognostic (1.85e-1)" "unprognostic (4.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (3.93e-10)" "unprognostic (6.13e-3)" "unprognostic (2.43e-1)" "unprognostic (9.10e-3)" "unprognostic (1.57e-1)" 0.1 0.1 2.0 3.1 3.5 0.0 1.6 1.8 2.8 0.3 1.3 35.6 27.7 0.0 0.7 4.8 0.4 0.8 0.0 2.1 2.5 10.8 2.1 0.2 0.4 1.9 2.9 0.1 0.8 0.9 0.1 0.5 2.2 0.1 33.1 0.1 0.5 3.8 0.7 1.0 19.8 1.2 1.5 14.3 25.4 0.6 2.9 0.5 31.1 0.6 3.0 0.7 0.2 3.7 23.4 1.0 0.0 0.2 7.3 10.3 0.0 7.1 35.0 13.6 23.1 0.7 10.7 0.0 15.0 9.4 2.7 17.3 0.3 1.1 11.2 0.0 3.7 0.0 0.2 0.0 2.7 0.0 1.1 2.2 0.9 18.9 1.6 5.3 8.7 0.0 0.0 0.3 66.1 2.3 0.0 0.1 1.9 0.3 1.4 0.0 0.0 12.5 51.5 0.3 0.1 0.0 5.4 0.2 0.1 3.9 1.2 0.1 0.0 0.2 1.2 19.8 0.4 0.0 0.0 0.0 18.1 0.0 177.2 0.0 0.0 0.0 1.6 0.0 24.1 0.0 0.9 8.2 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.8 2.0 3.5 1.8 2.8 2.1 2.5 1.9 2.9 2.2 1.5 2.9 3.7 0.2 0.0 0.0 0.0 0.6 1.8 0.6 25.4 1.2 0.0 6.8 0.4 0.3 28.6 9.2 7.3 0.0 0.2 0.0 106.0 15.6 6.9 0.0 0.2 0.1 0.9 2.4 0.0 0.3 9.9 0.4 1.4 29.6 0.5 0.0 0.0 0.7 1.5 1.3 0.0 0.3 21.2 40.7 0.0 0.4 0.0 0.0 0.1 1.8 1.9 0.0 0.0 5.2 1.0 9.7 10.4 63.4 0.0 0.1 0.8 41.9 8.9 4.4 0.0 0.0 0.0 0.4 0.2 1.7 6.5 1.7 0.5 1.0 0.0 51.4 1.0 TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 66.5;Proximal tubular cells: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (1.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (9.81e-3)" "unprognostic (2.05e-3)" "unprognostic (3.17e-2)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (4.90e-1)" "unprognostic (6.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" 3.2 8.0 6.6 4.8 7.1 1.0 6.8 7.4 7.7 5.3 3.3 10.9 16.1 6.6 9.0 5.7 10.6 3.9 8.2 6.8 4.6 13.4 25.7 3.3 5.1 4.2 6.2 7.9 5.5 8.2 12.5 3.2 4.5 5.9 9.1 7.2 6.9 5.9 12.2 6.7 13.7 5.2 3.9 4.0 6.3 7.7 6.6 4.7 5.6 7.0 5.2 5.2 4.9 6.6 22.9 19.9 17.2 16.7 4.6 4.5 8.9 8.4 10.4 24.3 18.3 50.4 12.6 37.9 20.1 7.4 19.9 13.7 27.9 28.7 14.0 18.0 51.4 19.5 11.8 56.7 10.1 12.5 13.9 12.4 20.1 19.2 12.5 9.3 15.7 22.3 30.7 4.9 13.3 19.0 21.8 24.3 44.0 16.7 29.2 19.6 16.8 22.4 24.4 11.8 33.8 19.3 10.9 23.2 26.9 15.9 17.7 21.1 12.8 12.0 28.7 9.2 16.7 4.9 3.8 23.3 4.5 15.2 22.0 0.0 2.6 2.6 8.2 2.1 8.5 6.6 6.9 8.4 4.9 8.7 16.2 10.3 0.8 7.2 1.4 5.8 7.9 5.5 6.6 7.1 7.4 7.7 6.8 4.6 4.2 6.2 4.5 3.9 6.6 6.6 2.6 3.2 0.0 3.3 3.6 2.9 12.1 13.9 1.8 13.3 8.2 9.7 13.0 11.5 10.7 5.5 14.6 11.9 2.1 8.9 66.5 16.0 2.2 4.0 6.8 5.0 2.4 3.4 4.1 14.3 9.7 5.4 5.6 2.8 0.0 10.1 1.4 30.5 6.3 11.8 4.1 7.2 8.2 1.2 1.1 2.1 7.5 1.5 14.2 0.0 4.7 9.4 5.2 5.5 2.0 12.3 6.5 12.4 3.4 9.2 22.8 47.2 5.4 21.8 0.0 2.6 6.1 6.5 6.6 5.1 2.0 2.1 4.1 21.5 14.1 4.5 TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 11.3;parathyroid gland: 11.9;tongue: 12.2" "Group enriched" "Detected in many" 5 "Astrocytes: 175.0;Excitatory neurons: 584.8;Inhibitory neurons: 566.2;Oligodendrocyte precursor cells: 306.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 6.0;HDLM-2: 5.7;NTERA-2: 5.1;RPTEC TERT1: 8.2;SCLC-21H: 6.4;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" 0.3 1.4 3.7 0.6 5.4 0.0 0.5 0.2 7.4 0.3 0.0 0.8 0.0 0.8 0.4 0.7 0.3 0.3 11.3 7.0 5.0 1.3 0.0 0.3 1.4 1.5 5.9 0.1 0.9 11.9 4.2 0.0 5.6 2.3 0.3 5.5 1.2 0.5 4.6 0.2 0.4 1.0 0.6 0.7 0.3 0.5 5.2 1.4 8.5 12.2 3.1 0.5 0.2 1.9 0.0 0.1 0.0 0.0 0.5 0.2 1.5 0.1 2.3 0.7 0.8 0.0 0.0 1.9 2.0 0.1 0.5 0.0 6.0 0.0 1.9 5.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 5.1 0.0 0.0 0.4 0.9 2.6 8.2 2.4 6.4 3.9 0.1 0.2 0.9 1.2 0.8 0.0 0.0 0.1 0.9 2.7 0.0 0.0 0.0 0.0 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.2 7.4 7.0 5.0 1.5 5.9 5.6 0.6 5.2 1.9 1.3 0.0 0.0 175.0 0.0 0.5 0.7 0.9 0.6 25.5 1.4 0.5 48.7 0.0 1.3 1.8 2.1 0.0 0.0 0.0 1.9 0.1 1.3 0.2 0.1 1.2 0.0 0.0 584.8 0.4 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 30.3 566.2 0.0 2.0 0.0 0.0 1.6 0.0 0.1 1.8 24.4 0.0 4.2 0.0 306.1 81.3 0.8 0.0 0.7 0.0 2.2 0.0 3.4 0.2 1.8 0.0 3.9 0.8 1.4 0.7 2.9 0.1 0.3 0.3 0.2 0.1 2.0 TMEM179B ENSG00000185475 "Transmembrane protein 179B" Q7Z7N9 11 62787402-62790400 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016585, HPA062068" Enhanced "Nuclear speckles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear speckles" "HPA016585: AB_1844357, HPA062068: AB_2684676" "unprognostic (1.18e-2)" "unprognostic (2.83e-1)" "unprognostic (2.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.68e-1)" "unprognostic (6.11e-3)" "unprognostic (1.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.44e-1)" "unprognostic (1.25e-2)" "unprognostic (4.61e-3)" "unprognostic (2.76e-2)" "unprognostic (4.56e-1)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (5.74e-3)" "unprognostic (3.60e-2)" 52.1 60.3 32.4 22.0 34.7 21.5 55.0 33.7 36.4 50.5 41.8 48.7 34.7 44.4 71.2 47.9 46.7 28.4 34.0 30.8 32.9 54.3 64.3 51.0 26.9 35.3 33.3 39.6 58.7 34.1 31.0 30.0 35.6 45.8 40.1 10.4 59.1 26.4 27.2 58.2 49.8 26.3 33.7 48.1 53.9 41.6 33.0 33.0 55.4 21.6 29.8 43.3 46.0 36.9 35.6 68.8 17.7 35.7 136.3 34.3 22.6 38.2 47.5 29.8 34.2 39.3 82.9 16.5 53.1 78.0 44.2 64.8 33.4 35.4 23.2 48.6 44.9 24.1 29.2 36.3 90.8 30.9 32.2 65.8 55.8 57.1 70.0 60.0 30.3 46.9 33.2 46.3 34.5 81.1 40.2 59.5 26.5 76.8 74.6 26.5 28.8 86.1 57.7 42.6 24.4 26.7 49.3 65.3 70.4 35.8 76.2 37.8 42.2 39.6 29.4 73.3 32.2 51.2 32.5 22.6 57.0 19.0 47.3 302.9 300.4 332.7 149.4 305.0 147.9 169.2 135.5 144.9 198.2 140.6 118.2 117.3 224.3 140.2 305.9 366.1 146.6 282.5 32.4 34.7 33.7 36.4 30.8 32.9 35.3 33.3 35.6 33.7 33.0 36.9 119.6 60.9 59.2 15.3 52.7 68.7 73.9 175.6 86.0 12.4 108.0 122.2 1.3 65.8 121.1 60.7 0.0 174.5 71.7 91.2 37.2 138.1 5.8 75.2 54.5 83.7 65.2 40.4 9.9 149.0 160.5 76.8 54.6 66.5 54.6 43.8 69.9 81.9 133.2 8.4 9.0 103.5 128.1 63.7 83.0 11.0 75.8 76.5 106.7 12.2 98.3 74.4 91.6 16.1 28.1 124.0 137.1 45.9 93.9 97.1 179.4 87.5 122.9 14.7 65.7 50.5 57.8 120.8 100.5 93.2 76.0 185.1 60.0 90.4 94.8 97.5 TMEM203 "HBEBP1, MGC14327" ENSG00000187713 "Transmembrane protein 203" Q969S6 9 137204082-137205648 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "unprognostic (1.31e-1)" "unprognostic (2.65e-2)" "unprognostic (4.53e-2)" "unprognostic (8.72e-2)" "unprognostic (1.10e-1)" "unprognostic (6.54e-2)" "unprognostic (2.72e-2)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (7.16e-2)" "prognostic favorable (4.78e-6)" "unprognostic (2.94e-1)" "prognostic favorable (1.50e-5)" "unprognostic (3.50e-3)" "unprognostic (1.57e-1)" "unprognostic (4.04e-2)" "unprognostic (1.19e-1)" 25.7 32.6 32.8 17.2 33.6 10.9 25.5 33.8 36.8 28.1 33.1 30.2 22.2 29.9 26.4 31.4 24.2 16.4 45.9 32.9 33.4 33.2 49.2 20.5 27.0 33.6 33.6 27.7 26.2 30.7 25.6 15.9 33.4 27.1 18.2 16.4 26.8 21.8 49.7 43.6 28.5 16.9 32.8 30.4 30.1 19.1 34.9 20.3 25.1 45.9 22.7 27.8 27.6 33.0 38.0 39.3 36.5 60.7 53.1 41.1 43.6 48.4 46.6 55.1 41.1 32.6 33.3 39.0 45.7 42.2 53.0 72.6 45.3 48.1 32.1 71.0 43.5 27.0 45.5 37.4 44.3 63.1 26.8 39.6 75.4 36.0 47.4 36.8 35.8 50.5 64.2 44.4 43.2 65.2 50.5 54.6 60.8 72.4 63.2 54.2 51.1 78.2 46.5 27.2 48.3 47.3 38.6 48.8 39.2 25.0 68.8 50.6 32.0 56.3 30.1 63.6 55.1 23.8 80.0 49.5 43.5 46.3 47.3 4.7 3.8 4.1 5.2 4.3 6.4 8.3 5.8 6.5 4.6 4.5 8.7 6.0 1.9 7.5 3.9 4.8 4.0 2.6 32.8 33.6 33.8 36.8 32.9 33.4 33.6 33.6 33.4 32.8 34.9 33.0 23.2 9.6 6.8 4.6 21.4 17.6 22.7 7.0 23.9 33.6 29.6 33.8 13.5 40.0 7.9 31.3 4.2 30.5 23.7 15.9 52.8 49.4 3.5 15.3 24.2 20.7 16.3 29.8 5.7 42.0 26.3 22.3 14.8 13.3 5.7 31.7 21.4 41.1 29.3 32.0 6.2 13.4 10.2 27.1 13.2 9.4 22.1 20.8 24.9 5.6 54.2 58.8 24.7 2.5 6.1 41.7 10.8 20.7 13.3 37.2 18.5 59.2 4.9 25.7 13.1 19.5 32.5 18.6 15.9 28.5 27.3 19.4 24.4 36.2 18.6 17.9 TMEM205 "MBC3205, UNQ501" ENSG00000105518 "Transmembrane protein 205" Q6UW68 19 11342776-11346518 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 405.8;Hepatocytes: 520.1;Late spermatids: 662.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041504 Approved Approved "Nucleoplasm,Nuclear membrane,Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum" "Nucleoplasm, Nuclear membrane" "HPA041504: AB_10795595" "unprognostic (2.54e-2)" "unprognostic (2.60e-2)" "unprognostic (7.19e-2)" "unprognostic (1.57e-2)" "unprognostic (6.83e-2)" "unprognostic (1.80e-1)" "unprognostic (5.04e-3)" "unprognostic (3.77e-2)" "unprognostic (1.01e-2)" "unprognostic (5.56e-3)" "unprognostic (2.70e-2)" "unprognostic (1.19e-1)" "unprognostic (8.10e-2)" "unprognostic (5.78e-2)" "unprognostic (8.18e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" 70.3 177.5 111.5 36.8 113.2 55.2 76.0 110.7 142.9 92.8 135.4 73.8 62.3 69.5 92.6 53.7 85.2 61.1 119.7 117.2 122.4 139.2 276.9 73.9 38.9 112.8 113.1 86.8 155.0 210.0 97.4 53.6 114.0 93.2 36.4 25.9 92.4 78.7 122.2 74.3 57.2 42.2 113.6 62.6 86.3 78.8 113.6 39.3 132.1 66.0 34.1 92.4 64.0 122.7 95.5 229.7 28.5 96.2 54.1 64.5 52.6 35.2 80.9 75.9 59.4 70.0 29.5 84.7 209.3 71.6 74.5 95.6 40.5 106.6 50.5 100.7 39.2 23.0 76.5 117.7 135.9 38.9 69.8 61.3 106.7 48.7 81.0 78.5 92.3 79.9 70.4 349.8 47.0 238.8 58.6 108.9 49.9 123.0 174.5 54.3 43.4 225.9 186.9 169.0 50.2 76.7 37.3 151.1 88.1 33.1 132.2 111.3 54.0 94.3 36.2 104.4 80.2 207.0 225.3 51.5 90.4 172.2 74.0 31.8 336.5 36.7 67.2 150.0 67.9 112.7 54.7 58.5 208.2 95.8 43.9 52.2 52.6 55.8 91.0 150.9 73.7 175.8 111.5 113.2 110.7 142.9 117.2 122.4 112.8 113.1 114.0 113.6 113.6 122.7 80.5 67.3 70.5 40.1 44.1 51.5 135.9 281.3 62.0 32.5 113.3 134.4 68.5 175.8 202.3 152.6 12.5 123.7 27.7 53.7 60.7 159.2 405.8 63.2 65.8 72.4 117.6 14.5 30.8 162.7 83.0 76.4 26.0 97.0 29.2 45.4 69.3 520.1 94.4 26.9 27.3 81.4 136.3 67.5 50.0 662.3 80.8 61.2 96.0 5.6 62.1 91.9 19.6 17.6 22.2 97.7 68.6 68.1 70.7 136.7 104.1 224.6 69.3 33.1 46.0 76.3 70.9 38.1 15.6 46.4 54.0 96.7 29.8 101.6 79.3 130.9 TMEM236 "bA162I21.2, bA16O1.2, FAM23A, FAM23B" ENSG00000148483 "Transmembrane protein 236" Q5W0B7 10 17752201-17800868 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "intestine: 33.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 81.1;Enteroendocrine cells: 23.4;Intestinal goblet cells: 28.8;Paneth cells: 48.1;Proximal enterocytes: 96.5;Undifferentiated cells: 19.0" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.7;pancreatic cancer: 0.5;stomach cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "MOLT-4: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA045096 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA045096: AB_2732516" "unprognostic (4.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.88e-3)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (3.36e-2)" "unprognostic (2.52e-3)" "unprognostic (1.37e-1)" "unprognostic (3.98e-1)" "unprognostic (1.42e-1)" "unprognostic (5.06e-3)" "unprognostic (1.75e-1)" "unprognostic (1.62e-2)" "unprognostic (1.72e-1)" "unprognostic (3.43e-2)" "unprognostic (3.16e-2)" "unprognostic (1.54e-2)" 0.7 0.6 0.3 1.7 0.3 0.5 0.4 0.8 0.5 0.5 0.4 14.1 21.8 0.3 0.2 0.3 0.2 0.4 0.3 0.3 0.1 0.2 0.1 0.7 0.3 0.1 0.0 0.3 0.5 0.1 0.0 1.5 0.2 0.1 14.0 0.3 0.1 0.2 0.3 0.3 33.5 1.0 0.0 0.3 0.4 0.2 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.7 0.2 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.3 0.3 0.2 0.0 0.2 0.9 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.1 0.2 0.1 0.2 10.3 0.1 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.8 0.5 0.3 0.1 0.1 0.0 0.2 0.0 0.1 0.7 0.2 0.0 0.5 0.0 0.2 0.1 0.5 0.0 0.0 0.3 7.3 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.1 81.1 0.0 0.1 1.1 0.1 0.1 0.2 23.4 0.4 0.4 0.9 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.0 7.2 0.0 0.4 28.8 0.0 4.8 0.8 1.1 0.0 5.9 0.0 3.7 0.0 0.1 0.0 0.0 0.6 0.7 48.1 0.0 0.0 0.4 96.5 0.0 0.0 0.9 0.0 0.7 0.3 0.4 0.1 0.2 0.0 0.3 0.4 0.2 19.0 0.6 TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 113.5;Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" 16.6 22.9 7.3 6.4 7.8 2.7 16.9 7.9 10.0 15.5 8.2 22.9 10.3 14.2 16.5 13.1 14.7 6.7 25.6 7.6 7.6 33.2 17.2 17.1 8.0 7.7 7.8 14.2 21.2 10.3 19.8 6.9 7.8 25.7 12.5 20.7 19.6 9.2 30.6 13.7 18.1 6.8 7.4 15.9 21.8 8.4 8.1 8.6 17.6 12.4 6.9 17.2 12.8 9.0 11.0 12.1 15.3 16.1 17.2 7.3 9.4 7.9 8.2 12.7 16.2 7.8 11.1 12.1 12.9 7.9 15.9 15.9 17.8 12.6 17.7 9.3 13.4 10.9 8.8 18.3 15.2 16.0 14.7 9.3 14.6 10.0 16.2 6.8 12.2 13.5 9.3 12.0 11.6 52.5 10.2 12.8 8.3 28.0 11.6 4.7 16.0 11.3 16.6 23.6 12.9 13.4 11.7 6.0 36.9 12.4 17.7 11.4 5.0 6.1 10.8 14.6 9.4 9.3 16.0 11.8 11.4 6.1 9.1 6.8 9.7 13.6 3.9 9.4 2.9 4.7 4.6 4.4 8.0 5.5 5.2 5.9 10.5 5.3 13.0 7.3 4.1 4.2 7.3 7.8 7.9 10.0 7.6 7.6 7.7 7.8 7.8 7.4 8.1 9.0 13.4 3.2 14.4 5.2 22.4 23.2 37.9 33.6 13.1 14.8 41.1 39.1 22.5 32.9 22.0 31.3 27.1 36.6 16.5 44.8 113.5 30.3 1.8 33.1 16.3 11.9 15.0 11.3 5.9 26.6 21.1 16.6 20.9 35.7 17.2 15.2 8.9 19.2 110.1 13.5 7.8 36.1 26.4 28.4 20.0 2.3 11.8 39.6 32.0 2.8 16.2 34.8 12.3 5.0 13.8 17.7 23.8 10.9 13.1 43.3 31.7 69.6 17.2 30.6 39.5 13.9 23.2 4.5 17.8 18.1 31.1 27.4 16.1 17.6 30.9 36.4 TMEM30B CDC50B ENSG00000182107 "Transmembrane protein 30B" Q3MIR4 14 61277370-61281761 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 124.0;Prostatic glandular cells: 101.1;Urothelial cells: 131.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 68.7;CAPAN-2: 54.4;HaCaT: 31.7;HBEC3-KT: 39.0;hTCEpi: 29.1;MCF7: 44.6;RT4: 94.9;T-47d: 30.4" "Not detected" "Not detected" HPA043162 Uncertain NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043162: AB_10796688" "unprognostic (4.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (3.47e-2)" "unprognostic (2.01e-1)" "unprognostic (6.20e-2)" "unprognostic (2.45e-3)" "unprognostic (3.43e-2)" "unprognostic (9.10e-2)" "unprognostic (2.20e-1)" "unprognostic (5.10e-2)" "unprognostic (2.26e-1)" "prognostic favorable (5.89e-5)" "unprognostic (2.21e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (1.85e-1)" 3.9 1.6 0.5 3.7 0.7 0.4 14.8 0.5 1.0 16.4 0.9 29.1 43.3 3.8 28.2 14.1 15.2 23.9 2.0 0.3 0.7 12.3 12.3 14.5 1.2 0.6 0.5 2.5 35.7 59.1 18.2 5.7 0.5 21.9 26.1 0.3 27.7 13.4 1.2 8.6 34.4 1.7 0.5 0.7 42.2 2.6 0.6 5.3 50.0 1.9 4.4 16.1 9.3 0.4 68.7 0.2 0.0 0.0 6.7 1.6 0.1 0.1 0.0 0.0 0.0 11.6 54.4 0.0 0.1 0.0 0.0 31.7 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 29.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 44.6 0.0 0.1 0.6 28.2 1.6 0.0 1.5 0.2 0.0 94.9 11.2 0.1 0.8 25.6 0.1 1.9 30.4 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.3 0.1 0.0 0.0 0.7 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.5 0.7 0.5 1.0 0.3 0.7 0.6 0.5 0.5 0.5 0.6 0.4 0.6 28.9 31.9 0.0 0.6 64.9 124.0 19.5 61.5 0.0 32.2 16.5 1.9 47.1 24.5 40.5 0.0 28.0 1.1 90.8 13.7 24.8 0.9 23.8 3.9 3.9 23.4 0.0 0.0 37.2 11.4 5.5 62.7 45.3 2.5 0.7 4.2 14.1 2.0 0.0 0.0 73.1 20.3 1.0 6.8 1.6 8.7 1.5 5.4 1.0 0.6 2.9 2.1 0.0 0.1 31.9 75.3 79.0 0.4 101.1 73.6 1.0 22.7 0.3 13.1 2.4 5.4 5.9 3.6 43.3 63.6 35.8 3.6 0.9 64.7 131.9 TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.1;liver: 100.0;parathyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.9;Hepatocytes: 184.5;Muller glia cells: 146.8;Proximal enterocytes: 575.7;Proximal tubular cells: 188.1" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "EFO-21: 26.9;Hep G2: 74.7;RPTEC TERT1: 60.0" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" 53.1 11.1 2.1 6.6 2.0 0.7 25.6 1.8 3.6 21.9 2.5 37.3 53.5 6.4 4.8 6.8 3.4 23.2 4.8 1.5 1.8 101.1 100.0 15.4 10.2 2.5 2.1 12.7 13.3 124.7 1.0 14.9 2.3 3.9 19.0 23.6 7.0 7.6 2.4 10.5 76.1 4.8 2.5 25.7 18.1 5.1 3.7 3.0 31.1 4.2 4.9 7.0 5.6 3.2 0.0 7.3 0.7 0.3 4.3 0.4 1.0 0.2 0.1 0.0 0.1 11.4 6.4 0.0 26.9 3.4 0.6 1.7 3.0 0.0 0.0 0.0 2.9 1.0 4.0 74.7 5.9 0.0 0.1 9.7 0.0 0.0 0.0 0.2 5.9 0.0 0.2 10.9 0.0 0.7 0.0 0.8 5.4 0.1 0.2 0.0 0.1 9.9 60.0 4.9 0.9 0.4 0.3 2.9 0.0 5.0 1.2 1.7 3.8 0.0 10.4 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.1 2.0 1.8 3.6 1.5 1.8 2.5 2.1 2.3 2.5 3.7 3.2 12.2 25.6 9.6 0.0 3.2 2.0 0.3 11.1 0.0 2.4 1.8 1.5 2.1 82.9 13.6 18.4 0.0 64.9 0.1 179.9 50.9 36.1 0.3 7.7 98.8 15.1 9.1 5.3 0.0 52.3 3.8 17.9 11.7 10.3 1.3 16.4 61.8 184.5 64.6 6.7 0.0 22.0 14.2 65.5 5.0 1.9 49.7 19.5 1.8 0.0 0.6 146.8 0.0 0.0 0.6 15.3 68.1 3.8 0.0 0.1 575.7 188.1 7.6 17.4 0.0 0.9 14.8 0.0 0.8 1.0 2.8 104.1 2.4 45.3 23.3 2.3 TMEM59 "C1orf8, HSPC001" ENSG00000116209 "Transmembrane protein 59" Q9BXS4 1 54026681-54053504 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075447 Approved NA NA 27000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA075447: " "unprognostic (2.63e-1)" "unprognostic (9.88e-2)" "unprognostic (2.63e-2)" "unprognostic (2.86e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.63e-2)" "unprognostic (8.28e-2)" "unprognostic (4.10e-1)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (4.49e-2)" "unprognostic (6.34e-3)" "unprognostic (9.84e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-3)" "unprognostic (7.38e-2)" 257.6 359.7 181.9 164.6 220.8 259.7 341.4 240.3 253.8 343.6 379.5 488.3 364.1 208.7 415.5 241.8 403.2 299.3 275.7 178.4 202.0 473.7 505.7 264.0 162.6 240.6 205.0 225.4 586.1 532.5 170.2 325.8 239.1 350.2 485.3 254.2 550.3 279.9 194.5 194.7 369.1 219.8 235.7 188.7 433.0 174.9 204.6 186.9 341.3 247.6 189.2 289.2 202.6 286.8 188.9 122.3 142.8 185.2 844.1 371.1 182.8 347.9 499.1 211.5 276.0 99.1 391.9 96.7 322.6 595.6 257.7 281.1 166.2 237.5 221.9 237.7 177.4 133.5 266.6 166.1 317.8 165.7 268.7 408.3 411.2 207.5 219.2 566.9 246.6 127.8 158.9 326.3 245.1 91.6 97.9 137.3 201.0 528.3 226.3 94.0 251.6 403.2 257.6 248.0 208.2 173.3 381.5 386.0 398.3 266.2 184.9 348.4 259.3 259.8 90.7 193.3 187.8 289.0 338.7 114.5 349.4 275.4 222.3 1183.5 654.6 831.5 439.7 532.9 461.8 449.3 465.9 480.4 520.9 405.2 430.3 426.4 1196.5 430.4 595.9 527.1 576.1 1153.8 181.9 220.8 240.3 253.8 178.4 202.0 240.6 205.0 239.1 235.7 204.6 286.8 355.3 233.9 181.3 49.6 221.3 404.2 637.0 1214.2 237.3 150.2 409.0 325.1 155.1 479.0 991.8 437.7 118.9 477.7 244.5 905.2 160.4 527.8 357.1 348.5 201.9 279.5 408.2 277.0 44.3 352.5 528.7 410.6 226.8 217.2 155.2 89.5 334.4 413.2 320.2 132.9 42.1 672.8 1131.1 302.9 290.3 183.1 432.7 225.4 690.1 27.2 209.3 473.5 190.5 60.3 176.6 329.3 1064.8 354.0 692.8 583.2 1015.8 468.8 977.4 183.6 368.1 198.6 350.4 488.9 210.1 245.5 414.3 687.1 227.2 185.8 534.9 750.4 TMEM9B C11orf15 ENSG00000175348 "TMEM9 domain family member B" Q9NQ34 11 8947202-8965011 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037784 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA037784: AB_10671886" "unprognostic (3.18e-1)" "unprognostic (4.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.84e-3)" "unprognostic (1.13e-1)" "unprognostic (8.48e-3)" "unprognostic (2.56e-2)" "unprognostic (6.34e-2)" "unprognostic (1.52e-1)" "unprognostic (3.78e-2)" "unprognostic (1.89e-2)" "unprognostic (5.06e-1)" "prognostic favorable (4.26e-5)" "unprognostic (1.83e-1)" "unprognostic (1.82e-1)" "unprognostic (5.51e-3)" "unprognostic (9.56e-2)" 34.2 40.0 67.6 33.8 70.5 78.0 47.9 70.1 80.8 37.0 62.3 63.6 54.6 22.2 59.0 62.4 31.4 39.5 53.3 65.1 69.3 60.2 39.8 50.7 40.5 70.6 69.5 24.1 41.4 63.9 38.5 45.2 71.5 34.2 67.0 42.3 51.4 26.0 47.4 45.5 54.8 22.2 70.8 41.7 59.3 27.5 72.0 35.6 75.0 42.9 43.3 47.3 35.9 75.2 63.0 42.4 23.7 46.0 117.1 65.9 41.1 78.4 69.3 45.2 46.3 32.4 96.7 39.1 40.3 81.6 53.2 81.9 22.3 57.5 47.3 72.7 45.0 26.2 36.8 31.0 66.3 53.2 79.5 61.1 94.6 27.9 56.0 61.7 54.5 26.4 21.0 58.0 87.2 43.9 16.6 33.9 7.4 90.1 49.5 18.8 30.4 31.6 67.7 72.4 26.4 22.5 44.8 92.3 40.6 29.7 55.7 35.1 59.4 55.0 24.9 93.7 48.6 24.1 44.7 27.8 69.0 35.0 47.5 178.7 104.5 151.8 98.5 134.7 101.7 103.2 94.3 109.8 112.6 89.3 77.7 109.0 50.5 93.3 150.2 80.7 136.8 159.8 67.6 70.5 70.1 80.8 65.1 69.3 70.6 69.5 71.5 70.8 72.0 75.2 61.5 41.7 52.0 17.9 65.7 65.0 65.5 155.5 58.6 61.0 67.5 35.9 28.6 70.1 104.1 95.6 20.9 104.8 69.6 124.0 70.5 84.5 16.4 29.2 28.0 49.3 31.2 111.6 21.9 80.7 112.9 48.0 34.7 43.8 88.1 21.1 55.0 30.5 109.3 43.7 23.2 78.8 213.6 79.0 109.8 13.4 38.2 70.1 60.5 15.9 58.1 82.6 77.2 24.1 33.8 70.9 103.9 28.6 53.6 59.2 114.7 45.7 53.2 49.2 19.7 41.6 26.2 56.4 58.2 83.7 87.4 160.8 66.8 40.3 82.8 80.6 TMIGD3 AD026 ENSG00000121933 "Transmembrane and immunoglobulin domain containing 3" P0DMS9 1 111483348-111563962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 55.1" "Cell type enhanced" "Detected in some" "Early spermatids: 272.5;Hofbauer cells: 236.3;Kupffer cells: 161.3;Late spermatids: 118.9;Spermatocytes: 198.3" "Cancer enriched" "Detected in all" 5 "glioma: 16.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 44 "eosinophil: 62.8" "Lineage enriched" "Detected in many" 44 "granulocytes: 62.8" "Cell line enhanced" "Detected in some" "HDLM-2: 7.0;HMC-1: 2.5;Karpas-707: 1.2;NB-4: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "prognostic unfavorable (3.58e-4)" "unprognostic (7.64e-3)" "unprognostic (7.47e-3)" "unprognostic (2.11e-2)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (9.48e-2)" "unprognostic (5.70e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (4.46e-2)" "unprognostic (9.50e-2)" "unprognostic (4.48e-2)" "unprognostic (5.69e-3)" "unprognostic (3.30e-1)" "unprognostic (1.44e-5)" "unprognostic (9.22e-2)" 0.8 3.3 1.7 1.3 3.0 2.0 0.8 2.2 3.2 0.6 1.2 0.8 0.3 0.2 0.0 0.7 0.4 0.7 0.4 2.3 2.6 0.2 2.6 0.7 0.9 4.4 4.5 0.2 0.2 0.4 0.2 4.6 4.8 0.3 0.5 0.3 0.3 1.3 0.1 0.1 1.5 0.8 3.0 1.4 0.6 55.1 3.9 0.6 0.2 0.5 0.4 0.4 0.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 7.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 3.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 62.8 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.3 0.3 0.6 0.0 0.6 1.7 3.0 2.2 3.2 2.3 2.6 4.4 4.5 4.8 3.0 3.9 6.1 1.0 0.0 2.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 272.5 0.0 0.0 5.1 0.0 2.7 0.7 0.2 1.9 0.3 0.0 0.0 0.0 0.0 5.3 1.2 236.3 0.0 0.7 0.0 0.0 161.3 0.0 118.9 3.7 59.5 0.0 29.0 1.3 0.5 0.0 0.5 4.4 0.0 0.0 1.2 0.0 0.1 0.0 0.5 0.0 0.3 13.1 0.0 0.1 198.3 2.6 0.1 0.0 2.9 0.7 0.2 0.0 0.1 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNIK KIAA0551 ENSG00000154310 "TRAF2 and NCK interacting kinase" Q9UKE5 3 171058414-171460408 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.7" "Cell type enhanced" "Detected in many" "Astrocytes: 1074.4;Excitatory neurons: 248.4;Inhibitory neurons: 360.8;Oligodendrocyte precursor cells: 374.5;Oligodendrocytes: 205.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 65.2;HMC-1: 71.3;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012128, HPA012297" Approved Supported Nucleoplasm,Cytosol NA NA 160000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA012128: AB_1858226, HPA012297: AB_1858225" "unprognostic (2.29e-1)" "unprognostic (1.12e-2)" "unprognostic (1.32e-1)" "unprognostic (5.90e-2)" "unprognostic (5.25e-2)" "unprognostic (9.23e-2)" "unprognostic (4.91e-2)" "unprognostic (2.41e-3)" "unprognostic (1.91e-1)" "unprognostic (7.81e-2)" "unprognostic (5.91e-2)" "unprognostic (1.96e-2)" "unprognostic (3.34e-3)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.13e-2)" "unprognostic (3.97e-2)" 1.4 4.4 25.7 6.2 33.7 4.4 2.1 4.1 17.5 1.3 0.0 8.2 21.0 3.4 0.9 4.1 2.8 5.1 9.4 20.8 15.7 3.8 3.1 8.9 6.7 25.5 18.7 1.5 3.7 0.5 8.4 1.9 6.3 3.5 6.7 19.4 1.9 4.6 23.2 1.0 21.3 4.3 19.0 4.5 7.0 7.7 20.1 7.0 6.3 23.6 5.3 4.8 2.1 10.7 0.9 1.2 43.4 4.7 0.8 0.1 10.4 9.3 2.5 7.3 4.8 41.5 16.9 0.0 3.4 9.0 6.9 14.1 6.3 2.6 7.3 0.3 9.8 65.2 3.7 0.0 19.0 13.0 71.3 6.1 5.9 4.3 0.9 15.7 43.6 10.5 23.3 0.1 1.1 1.1 4.1 13.5 18.2 30.6 17.9 0.0 11.8 16.6 12.0 0.1 2.1 2.3 5.8 0.4 9.6 4.1 20.4 2.9 0.5 0.0 7.9 20.5 7.1 0.1 0.0 0.1 1.8 13.8 52.1 4.6 0.1 10.5 3.5 0.0 4.4 0.0 4.2 3.2 0.0 0.2 5.8 3.1 0.1 2.4 0.1 0.0 5.3 1.0 25.7 33.7 4.1 17.5 20.8 15.7 25.5 18.7 6.3 19.0 20.1 10.7 0.7 6.4 50.4 1074.4 4.9 2.5 1.6 1.3 9.1 19.2 8.4 6.5 28.6 21.5 7.1 9.2 14.6 6.3 32.5 19.6 5.9 12.1 48.6 1.1 2.5 1.6 13.2 13.5 248.4 7.7 1.3 9.1 21.4 0.3 83.5 0.4 2.5 8.1 2.9 0.0 360.8 10.3 0.0 6.5 1.9 38.0 2.5 10.4 1.8 57.1 1.6 65.0 51.5 374.5 205.5 7.1 21.6 6.4 11.7 0.7 56.2 17.3 1.8 28.7 0.0 12.4 6.2 3.1 1.0 10.3 1.6 2.5 47.4 9.9 16.6 3.2 TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 498.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Approved Cytosol NA NA 140000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA038621: AB_10673177, HPA038622: AB_10675946" "unprognostic (8.39e-2)" "unprognostic (1.89e-1)" "unprognostic (2.18e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (8.89e-2)" "unprognostic (2.51e-1)" "unprognostic (8.53e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.11e-16)" "unprognostic (2.72e-1)" "unprognostic (1.46e-1)" "unprognostic (3.21e-2)" "unprognostic (1.29e-2)" 26.8 35.4 58.2 12.4 73.5 13.6 25.8 27.5 80.9 35.9 17.6 26.3 25.5 23.5 11.5 93.4 22.4 18.4 31.3 85.0 39.4 43.1 113.3 26.6 14.2 39.9 39.1 24.6 58.2 18.9 54.2 12.1 39.8 31.4 8.2 11.4 31.6 20.5 76.2 75.9 23.4 11.1 32.9 28.8 31.9 73.4 42.7 13.2 24.7 22.7 14.2 33.5 48.8 56.5 31.4 32.6 16.3 18.6 34.0 21.2 14.2 27.2 24.5 31.3 27.7 35.4 19.5 14.6 25.6 25.3 47.9 27.7 14.7 33.4 8.5 30.1 30.1 11.9 6.9 54.2 48.4 22.8 29.0 32.1 38.5 18.6 17.9 17.1 19.7 21.7 19.9 38.5 26.1 26.3 29.1 27.9 20.0 33.9 42.1 21.8 16.6 14.6 20.9 41.3 43.5 25.5 24.4 29.4 30.7 8.3 23.3 25.7 36.0 33.8 14.4 14.4 16.0 38.8 37.8 18.3 53.2 14.9 27.0 45.4 126.6 139.6 33.4 114.0 27.8 38.8 35.3 31.5 99.9 50.0 27.4 26.1 179.1 44.5 108.8 52.4 48.8 77.3 58.2 73.5 27.5 80.9 85.0 39.4 39.9 39.1 39.8 32.9 42.7 56.5 19.5 9.6 19.3 15.0 27.8 66.9 43.9 71.7 23.3 42.6 30.3 24.6 22.8 58.6 30.9 23.9 8.4 49.2 28.0 50.8 70.5 66.3 173.6 11.7 14.8 24.9 51.6 45.0 35.1 69.2 41.1 27.6 19.4 15.8 38.1 20.7 37.9 112.2 92.1 74.0 17.0 30.8 48.8 38.4 33.1 498.2 21.8 48.3 71.2 16.9 50.6 38.1 19.6 10.6 15.0 76.3 53.7 30.9 33.4 55.7 66.6 110.1 15.4 20.6 6.6 18.5 24.5 100.7 39.6 76.3 98.9 104.4 22.0 27.4 29.3 74.0 TOM1L1 SRCASM ENSG00000141198 "Target of myb1 like 1 membrane trafficking protein" O75674 17 54899387-54961956 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 103.7;Late spermatids: 184.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022916 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "HPA022916: AB_1858181" "unprognostic (1.50e-1)" "unprognostic (7.70e-3)" "prognostic favorable (1.61e-4)" "unprognostic (9.59e-2)" "unprognostic (1.59e-3)" "unprognostic (6.26e-3)" "unprognostic (1.18e-2)" "unprognostic (1.32e-1)" "unprognostic (2.49e-3)" "unprognostic (2.00e-2)" "unprognostic (2.14e-1)" "unprognostic (3.87e-2)" "prognostic favorable (3.81e-6)" "unprognostic (7.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (3.62e-2)" 7.8 16.5 5.7 7.1 6.8 1.4 32.9 7.7 6.9 36.5 19.8 33.6 106.9 12.6 45.1 21.1 35.0 19.0 8.0 4.9 6.2 78.7 108.2 17.1 5.2 4.8 5.9 4.8 42.4 64.9 12.9 6.8 4.1 32.9 36.4 19.1 32.8 20.1 2.7 20.6 60.9 8.5 6.4 4.2 54.7 15.4 6.2 7.9 57.5 3.4 12.0 12.1 12.1 6.0 48.6 50.3 8.8 59.6 0.2 0.5 0.6 25.2 39.9 24.0 33.8 33.1 48.3 0.2 62.2 22.7 36.5 31.4 47.9 52.6 36.0 1.2 59.7 72.3 43.5 52.4 50.2 0.4 0.2 21.3 83.8 22.5 124.2 44.0 14.5 14.3 30.9 0.4 23.7 45.1 2.1 0.7 21.1 90.1 36.1 0.6 39.2 29.2 108.5 61.2 42.2 48.5 24.8 41.5 60.1 41.9 102.7 7.0 17.8 13.3 1.9 31.7 45.3 0.9 37.1 1.1 22.4 0.2 28.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 5.7 6.8 7.7 6.9 4.9 6.2 4.8 5.9 4.1 6.4 6.2 6.0 1.1 22.4 21.6 15.3 1.9 15.8 17.2 21.3 19.4 14.3 30.4 26.7 4.9 27.1 20.6 36.8 22.9 8.9 0.8 37.4 103.7 60.8 82.5 29.4 6.0 0.9 18.7 3.8 57.0 44.9 3.7 4.2 36.7 29.7 1.3 16.4 1.8 43.2 3.1 15.2 28.6 55.2 8.2 1.3 1.2 184.0 2.8 3.1 12.4 7.5 3.2 12.7 0.0 40.7 20.2 52.0 30.4 3.0 0.7 26.0 86.1 93.2 20.1 19.0 6.6 4.9 6.5 2.5 6.6 28.0 17.8 3.1 1.2 21.5 42.8 18.5 TOP2A TOP2 ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 127.8;testis: 65.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 216.8;Granulosa cells: 117.5;Spermatocytes: 621.2;Spermatogonia: 269.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in some" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Nucleoli "CAB002448: AB_564035, HPA006458: AB_1858189, HPA026773: AB_1858190" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "unprognostic (2.28e-3)" "unprognostic (9.42e-3)" "unprognostic (1.80e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.92e-6)" "prognostic unfavorable (4.99e-4)" "unprognostic (6.21e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.83e-5)" "unprognostic (5.03e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.46e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" 2.2 2.5 0.2 20.0 0.2 42.0 5.4 0.1 0.7 5.0 1.1 17.8 18.1 3.9 0.3 29.0 1.5 2.6 1.2 0.2 0.2 1.2 2.8 4.1 40.3 0.2 0.8 1.0 0.9 0.3 0.3 15.9 0.5 1.4 19.8 0.1 4.3 0.5 0.3 15.3 17.0 7.6 0.2 9.9 8.9 65.7 1.1 127.8 1.9 0.2 42.5 6.0 9.6 0.4 212.6 275.6 343.1 158.0 16.8 33.9 76.3 283.3 151.5 255.0 224.2 130.5 157.6 339.4 140.1 96.7 152.7 326.5 266.8 113.5 339.5 182.7 177.8 224.8 167.9 216.7 1.6 318.4 228.6 7.4 9.2 179.8 181.4 55.1 136.3 216.5 247.5 225.8 279.2 72.6 372.3 209.6 143.0 152.4 108.3 310.7 531.9 141.3 61.6 133.3 201.6 144.6 229.3 281.4 89.4 198.2 236.9 143.2 90.3 167.0 233.2 195.5 276.7 128.4 154.9 290.7 94.3 214.9 285.0 0.2 0.0 0.0 0.2 0.0 0.0 0.6 0.3 0.3 0.1 0.1 0.0 0.0 0.1 1.4 0.1 0.0 2.4 0.4 0.2 0.2 0.1 0.7 0.2 0.2 0.2 0.8 0.5 0.2 1.1 0.4 1.0 0.0 2.0 0.3 17.4 11.7 3.7 15.0 2.2 0.0 18.7 17.1 1.3 2.8 5.8 0.0 0.0 72.9 6.1 19.8 0.0 0.8 20.3 12.7 15.8 9.3 0.0 216.8 0.2 0.0 92.4 23.3 23.0 10.0 0.0 117.5 20.7 5.4 83.5 0.0 0.1 34.2 18.3 33.9 13.2 19.1 4.7 14.1 1.8 0.0 2.6 0.0 3.1 0.0 0.1 0.3 3.5 1.9 31.3 3.1 3.4 0.1 1.8 0.0 72.3 0.5 19.5 621.2 269.6 45.1 6.1 8.9 14.8 4.3 61.0 6.9 TOP2B ENSG00000077097 "DNA topoisomerase II beta" Q02880 3 25597905-25664907 "Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Autism spectrum disorder, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004601, HPA024120, HPA050441" Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004601: AB_628384, HPA024120: AB_1858191, HPA050441: AB_2681127" "unprognostic (2.90e-2)" "unprognostic (5.17e-2)" "unprognostic (7.21e-3)" "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (7.86e-2)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (7.14e-2)" "unprognostic (1.08e-1)" "prognostic favorable (2.43e-4)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (7.93e-2)" 27.1 25.5 15.3 38.9 17.6 49.1 34.7 25.2 16.5 36.2 12.0 30.1 28.8 42.9 25.5 34.1 29.7 26.2 38.5 15.3 16.0 32.1 27.7 28.0 50.4 13.5 16.2 40.6 28.8 53.2 11.7 34.4 15.1 38.7 33.3 112.3 27.1 34.2 29.9 32.4 28.6 34.2 16.4 36.4 32.1 19.5 14.6 82.5 45.8 36.7 46.6 43.7 18.5 25.3 57.6 58.6 125.9 155.3 41.1 51.7 50.1 54.4 69.6 49.4 53.9 30.1 44.6 176.9 37.1 79.2 30.5 47.7 105.6 60.5 82.5 85.5 56.7 268.5 71.2 50.6 28.9 212.8 137.4 37.1 29.7 55.3 48.2 49.8 81.7 118.6 92.0 84.3 64.4 64.0 138.5 52.5 95.9 38.5 44.1 569.9 71.0 82.6 43.9 199.5 63.2 109.7 81.1 57.4 49.9 72.2 59.7 187.1 78.7 68.3 52.6 55.2 58.9 129.6 78.6 185.1 44.9 155.6 46.5 3.2 1.4 2.8 3.0 1.7 3.3 2.0 2.9 3.1 2.2 2.5 3.3 3.0 1.0 3.9 2.6 2.8 2.3 1.1 15.3 17.6 25.2 16.5 15.3 16.0 13.5 16.2 15.1 16.4 14.6 25.3 36.4 64.1 62.7 65.3 47.3 39.1 47.9 30.9 31.3 62.4 44.4 31.9 121.5 34.3 36.1 25.8 56.3 47.8 65.8 29.9 13.7 34.3 3.6 48.0 58.8 36.6 59.3 65.6 77.8 33.4 24.5 40.2 28.5 45.1 34.1 71.4 25.0 35.1 26.2 60.6 89.8 32.3 20.3 40.7 50.1 6.0 39.1 45.3 23.2 43.1 49.8 51.3 68.0 76.4 113.0 35.5 22.2 33.4 46.0 56.2 20.6 25.6 39.2 95.7 32.9 56.5 51.0 94.9 44.0 57.9 37.6 46.7 53.7 48.4 39.2 64.3 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 TPMT ENSG00000137364 "Thiopurine S-methyltransferase" P51580 6 18128311-18155077 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 76.4;liver: 68.8;thyroid gland: 76.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 144.6;Proximal tubular cells: 307.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019851, HPA062364" Enhanced NA NA 39000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA019851: AB_1858213, HPA062364: " "unprognostic (6.24e-2)" "unprognostic (3.16e-2)" "unprognostic (5.46e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (4.98e-2)" "unprognostic (2.25e-1)" "unprognostic (8.16e-2)" "unprognostic (4.36e-3)" "unprognostic (9.62e-2)" "prognostic favorable (1.41e-4)" "unprognostic (4.49e-2)" "unprognostic (3.40e-2)" "prognostic favorable (1.10e-4)" "unprognostic (7.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.39e-3)" 5.8 16.4 9.2 12.9 12.2 10.0 10.0 10.5 12.2 7.7 9.6 34.5 34.5 6.9 17.5 10.3 7.0 10.4 12.2 10.4 9.7 76.4 68.8 9.3 10.0 9.8 9.7 4.5 11.6 18.0 7.5 5.6 9.9 10.8 35.1 13.1 12.1 6.6 13.2 10.3 28.9 10.5 9.3 11.0 12.2 6.7 9.9 9.2 76.9 11.7 10.1 15.9 7.4 9.8 24.5 7.3 7.9 19.9 12.9 24.9 19.5 27.7 30.8 23.3 36.2 17.1 5.9 3.1 20.3 37.0 18.0 12.0 11.3 20.0 38.6 16.2 16.2 20.0 12.0 25.2 14.1 9.3 17.4 14.5 21.2 26.0 16.5 15.1 32.9 13.5 40.6 5.6 17.2 11.1 9.6 12.7 13.2 33.9 20.7 11.9 19.6 13.8 27.2 24.8 13.0 10.0 18.3 31.9 36.9 19.9 22.9 9.0 14.0 53.1 10.3 28.0 40.0 8.1 38.9 8.0 19.0 12.3 54.5 8.7 22.1 7.2 11.6 46.7 14.9 2.7 9.2 11.1 32.3 2.6 8.1 11.2 2.2 10.4 40.7 6.5 16.2 17.2 9.2 12.2 10.5 12.2 10.4 9.7 9.8 9.7 9.9 9.3 9.9 9.8 13.9 16.0 15.5 4.6 12.6 42.7 41.3 23.0 13.6 15.3 20.9 15.0 22.9 25.8 15.8 35.0 22.9 20.7 20.5 144.6 115.4 52.7 1.2 38.4 15.3 14.3 24.0 18.1 18.7 37.4 25.3 11.3 14.8 39.4 22.9 4.3 17.5 86.5 44.9 6.7 13.2 34.8 22.4 48.5 60.9 2.8 4.1 41.1 24.9 9.4 32.6 33.5 29.9 11.1 10.2 76.8 106.6 10.1 9.7 38.8 80.8 307.6 12.2 19.5 0.0 9.3 13.9 0.7 7.7 19.5 34.5 17.5 21.1 9.5 50.7 78.9 TPX2 "C20orf1, C20orf2, DIL-2, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 48.0;lymphoid tissue: 70.3;testis: 30.7" "Cell type enhanced" "Detected in many" "Erythroid cells: 90.7;Extravillous trophoblasts: 68.5;Granulosa cells: 46.6;Spermatocytes: 114.5;Spermatogonia: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.1;NK-cells: 3.6;T-cells: 8.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: AB_1858223" "unprognostic (2.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.43e-6)" "unprognostic (2.99e-1)" "unprognostic (7.56e-2)" "prognostic unfavorable (8.07e-7)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.68e-5)" "unprognostic (5.99e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.39e-1)" 1.9 1.4 0.9 13.0 0.9 48.0 2.7 0.8 1.0 2.3 0.5 11.6 9.4 2.4 0.2 13.2 0.9 1.8 0.8 1.1 0.6 0.7 4.2 1.9 26.6 0.6 1.0 0.5 0.4 0.4 0.2 8.3 0.7 0.7 14.2 0.5 2.0 0.5 1.4 9.8 9.4 6.8 0.6 5.2 6.2 30.7 1.3 70.3 1.0 0.8 32.3 3.4 4.1 0.9 455.1 149.1 176.4 139.1 13.8 25.2 169.8 186.1 104.5 264.0 197.7 319.1 190.4 212.4 106.7 104.5 196.8 232.7 203.7 169.0 298.8 92.3 78.8 416.3 139.7 219.6 4.2 161.9 102.8 8.7 9.1 166.0 120.0 37.9 144.6 157.1 313.8 187.8 209.7 186.2 272.2 125.3 197.1 174.0 159.3 152.5 475.5 128.2 71.2 72.8 127.5 85.7 284.6 106.3 82.0 120.9 185.1 97.3 98.3 294.1 179.7 136.5 290.0 74.4 138.6 187.3 92.2 565.1 195.8 5.1 0.0 0.4 0.4 0.0 0.2 0.6 1.4 1.7 0.5 0.2 0.3 0.5 0.2 3.6 0.1 1.0 8.1 1.0 0.9 0.9 0.8 1.0 1.1 0.6 0.6 1.0 0.7 0.6 1.3 0.9 1.0 0.0 4.2 0.0 5.9 6.9 1.5 4.3 1.2 0.9 3.0 3.4 0.9 4.3 3.8 0.0 0.0 23.3 3.8 6.4 0.0 1.2 9.3 7.3 6.6 3.9 1.2 90.7 2.9 0.4 68.5 9.2 16.3 8.4 0.0 46.6 8.9 3.0 19.5 1.7 0.9 9.8 10.2 8.0 5.5 13.1 0.9 7.6 0.0 1.0 2.1 0.4 3.1 0.5 0.5 1.8 1.4 0.0 30.8 2.5 0.9 0.0 0.7 0.4 0.0 1.1 15.4 114.5 63.1 31.2 6.1 4.7 8.2 4.2 18.4 2.9 TRAC ENSG00000277734 "T cell receptor alpha constant" 14 22547506-22552156 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in all" 7 "lymphoid tissue: 787.9" "Cell type enhanced" "Detected in many" "dendritic cells: 166.3;Rod photoreceptor cells: 75.9;T-cells: 428.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "MAIT T-cell: 2123.1;memory CD4 T-cell: 2939.7;memory CD8 T-cell: 2508.6;naive CD4 T-cell: 2671.8;naive CD8 T-cell: 2388.0;T-reg: 4379.2" "Lineage enriched" "Detected in all" 41 "T-cells: 4379.2" "Cell line enhanced" "Detected in many" "HDLM-2: 127.0;JURKAT: 294.7;NB-4: 83.1;U-266/84: 126.2;U-698: 62.1" "Low region specificity" "Detected in all" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "prognostic favorable (3.21e-4)" "prognostic favorable (4.87e-6)" "unprognostic (9.92e-3)" "prognostic favorable (4.15e-6)" "unprognostic (3.71e-2)" "prognostic favorable (5.25e-5)" "unprognostic (2.83e-2)" "unprognostic (9.81e-3)" "unprognostic (2.51e-3)" "unprognostic (1.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.99e-1)" "prognostic unfavorable (3.40e-5)" "unprognostic (2.13e-1)" "unprognostic (6.35e-2)" "unprognostic (1.33e-1)" "unprognostic (2.75e-2)" 17.5 7.7 5.4 157.5 14.8 29.5 16.9 6.9 3.9 12.0 2.4 33.6 46.6 9.3 39.3 17.2 10.0 42.2 45.3 2.0 2.0 10.5 16.5 47.0 394.3 3.4 8.2 7.3 3.3 1.9 11.4 2.3 4.0 15.3 43.4 112.7 25.8 5.5 3.3 19.5 78.3 10.4 2.5 134.1 54.9 7.2 2.2 787.9 12.2 2.7 287.6 58.4 9.7 2.3 0.3 0.0 11.6 0.0 0.0 0.0 0.2 0.1 0.4 0.3 0.4 1.8 0.0 11.4 1.5 0.0 0.2 0.0 0.2 0.1 1.1 127.0 0.0 0.2 0.0 0.0 0.0 16.4 0.8 0.0 0.0 4.3 0.2 0.0 3.1 294.7 0.4 0.1 1.2 0.0 45.7 83.1 3.1 0.1 0.6 22.9 2.8 0.2 0.7 0.0 0.0 0.2 0.0 0.0 1.1 1.7 0.0 1.6 8.3 3.4 0.7 0.3 1.0 2.7 126.2 62.1 1.0 0.5 0.1 24.5 10.2 9.8 520.5 6.7 2123.1 105.6 2939.7 2508.6 7.9 94.6 2671.8 2388.0 57.7 89.7 11.0 11.8 4379.2 2965.8 5.4 14.8 6.9 3.9 2.0 2.0 3.4 8.2 4.0 2.5 2.2 2.3 9.0 3.2 25.6 0.0 46.3 0.0 1.0 0.0 5.7 9.0 4.9 8.5 35.7 0.0 6.2 0.0 12.5 0.2 166.3 0.9 17.6 0.7 46.2 0.9 0.6 3.3 0.0 16.4 0.0 0.0 0.2 15.9 4.1 0.5 10.1 0.0 9.3 1.4 1.3 0.0 0.0 0.9 0.0 8.1 0.0 4.8 1.8 12.2 0.0 0.0 20.2 11.8 44.3 0.0 0.0 0.1 1.2 5.3 25.4 0.2 0.5 4.6 0.0 75.9 0.0 2.6 4.7 2.2 0.8 5.4 0.0 0.3 428.0 0.0 0.7 0.2 TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 75.3;Endometrial ciliated cells: 150.3;Late spermatids: 75.1;Respiratory ciliated cells: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 49: Ciliated cells - Cilium organization" "HPA037857: AB_2675706, HPA037858: AB_10671724" "unprognostic (1.25e-1)" "unprognostic (9.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.80e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (9.04e-2)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (4.78e-3)" "unprognostic (7.48e-3)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.07e-1)" 7.1 5.0 7.9 4.2 7.7 2.0 6.7 7.1 9.3 7.1 10.5 10.2 5.2 8.4 12.3 6.5 19.3 5.7 5.3 7.4 8.6 6.9 5.6 6.7 4.7 9.9 10.0 7.2 5.4 12.2 5.9 4.9 9.0 7.1 6.0 6.7 6.4 8.1 11.3 5.6 4.9 7.4 9.4 4.9 5.9 14.2 8.5 4.0 10.7 7.5 5.3 7.0 6.2 7.3 8.6 10.4 9.4 11.4 9.2 11.4 6.9 6.9 10.4 8.9 8.3 3.7 6.6 0.2 3.6 9.9 10.3 8.5 10.5 7.9 13.7 5.2 10.7 2.2 9.2 12.7 9.7 10.4 5.8 8.8 12.3 11.3 9.1 8.3 9.1 7.6 10.5 1.9 9.6 10.8 8.3 5.7 10.5 6.8 5.4 13.0 17.1 3.4 12.1 4.0 12.8 6.9 11.7 9.0 9.0 5.7 7.6 7.8 10.4 10.8 8.4 11.0 9.1 4.9 2.8 3.3 10.6 3.7 7.3 0.2 0.2 0.1 0.3 0.1 0.6 0.3 0.3 0.4 0.1 0.2 0.3 0.3 0.3 2.0 1.5 0.4 0.0 0.2 7.9 7.7 7.1 9.3 7.4 8.6 9.9 10.0 9.0 9.4 8.5 7.3 10.9 32.1 18.1 20.5 5.0 7.9 7.8 5.2 9.6 20.3 15.6 11.0 14.6 2.8 21.7 1.8 37.5 7.1 7.4 10.5 0.0 8.1 75.3 150.3 25.2 10.4 10.7 6.1 37.9 9.1 6.0 11.6 9.2 24.5 6.3 16.0 8.2 16.0 4.5 47.1 36.9 9.9 8.2 2.5 6.0 75.1 11.1 4.9 3.6 15.0 3.2 14.5 4.1 16.1 18.1 8.4 7.1 17.0 4.2 7.0 7.8 8.2 105.3 37.8 6.6 17.9 12.4 48.1 44.1 9.1 8.0 3.7 5.1 18.1 11.4 5.9 TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 670.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA023929: AB_1858239" "unprognostic (3.85e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (8.34e-3)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (5.93e-2)" "unprognostic (8.94e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.39e-3)" "unprognostic (3.61e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (7.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" 93.2 82.8 26.6 95.9 28.9 102.3 115.8 27.6 42.1 139.2 47.7 85.4 91.7 93.4 148.5 65.2 78.5 117.7 59.8 24.8 31.1 120.7 190.2 146.3 103.5 32.5 27.9 73.4 175.5 117.3 38.8 146.8 32.4 87.2 79.7 33.3 193.9 86.0 26.7 49.2 93.6 96.7 29.1 90.0 94.7 61.0 29.1 98.6 170.7 54.9 114.3 120.2 47.7 34.5 171.1 172.5 73.6 45.2 352.6 367.8 105.2 302.9 301.7 231.7 279.1 109.9 275.8 169.1 58.5 259.6 91.3 219.3 67.6 262.1 221.8 112.2 76.1 118.5 54.6 125.7 515.4 91.3 66.3 441.5 249.6 114.2 410.8 238.5 196.7 85.0 77.8 430.3 288.6 47.2 210.4 65.7 48.3 132.3 81.0 100.9 55.3 113.8 610.5 160.4 53.4 54.2 195.0 389.0 180.5 103.1 144.1 102.0 195.3 141.0 117.5 162.4 102.0 338.7 140.1 85.5 160.3 92.9 105.0 150.1 97.3 64.9 120.8 107.7 153.5 107.9 132.1 137.6 114.3 87.9 119.6 125.2 28.2 130.7 113.7 190.4 146.8 232.7 26.6 28.9 27.6 42.1 24.8 31.1 32.5 27.9 32.4 29.1 29.1 34.5 138.3 275.7 132.0 19.6 166.4 85.5 85.2 214.0 69.4 23.7 114.2 62.4 43.0 131.5 209.3 178.4 14.6 154.3 200.5 69.3 68.4 174.5 142.8 77.9 140.7 134.3 44.2 59.7 27.4 247.7 236.7 177.0 70.8 186.6 72.4 59.0 137.8 202.9 182.7 23.5 26.1 95.5 156.6 134.9 251.0 222.2 127.4 123.7 202.7 29.0 132.1 65.6 128.8 34.2 40.3 290.5 51.0 94.4 670.6 199.6 78.0 147.0 110.2 32.9 124.9 76.4 99.5 134.8 56.8 72.3 88.5 194.3 154.2 78.2 65.5 130.6 TRBC1 "BV05S1J2.2, TCRBC1" ENSG00000211751 "T cell receptor beta constant 1" 7 142791694-142793368 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 28 "lymphoid tissue: 1520.1" "Group enriched" "Detected in many" 10 "dendritic cells: 338.0;NK-cells: 580.9;T-cells: 399.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 3232.4" "Lineage enriched" "Detected in all" 9 "T-cells: 3232.4" "Cell line enriched" "Detected in some" 5 "JURKAT: 1467.5" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (1.08e-4)" "unprognostic (7.96e-4)" "unprognostic (6.02e-2)" "unprognostic (1.26e-4)" "unprognostic (1.81e-2)" "unprognostic (5.42e-5)" "unprognostic (1.76e-2)" "unprognostic (6.94e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-2)" "unprognostic (1.67e-2)" "unprognostic (3.56e-1)" "unprognostic (3.18e-6)" "unprognostic (3.98e-1)" "unprognostic (8.83e-3)" "unprognostic (1.02e-1)" "unprognostic (4.19e-3)" 9.2 5.1 1.3 140.0 1.5 53.5 9.5 1.1 2.1 7.7 1.5 18.5 26.8 6.4 5.7 12.0 7.0 26.7 5.0 1.0 1.1 5.4 11.4 31.5 322.2 2.0 1.2 6.4 2.7 0.9 2.0 2.3 1.7 9.0 19.4 0.0 19.0 4.6 1.0 9.9 49.7 4.2 1.7 92.5 27.1 2.7 1.6 1520.1 8.4 2.1 227.0 33.2 6.2 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.6 0.0 1467.5 2.0 0.0 0.0 0.0 0.0 1.7 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 296.5 2.0 0.0 1.9 0.0 45.6 7.2 4.7 869.6 3.5 693.8 17.1 1893.1 1259.3 5.8 15.7 1989.8 1450.7 37.3 359.8 8.3 9.7 3232.4 1917.5 1.3 1.5 1.1 2.1 1.0 1.1 2.0 1.2 1.7 1.7 1.6 1.9 7.3 19.2 40.8 0.0 11.7 0.0 0.3 0.0 0.0 0.0 5.9 5.5 0.0 0.0 3.1 1.8 0.0 0.2 338.0 0.0 0.0 0.5 0.6 1.1 0.7 1.5 0.0 10.7 0.0 0.0 0.1 3.2 4.6 0.8 20.2 0.0 5.3 1.5 0.3 0.0 0.0 0.1 0.0 8.4 0.0 1.9 17.4 13.9 0.0 0.0 17.3 0.0 580.9 0.0 0.0 0.0 0.1 8.2 23.6 0.3 0.0 2.4 0.7 0.0 0.0 1.1 3.5 0.0 0.1 0.5 0.0 0.1 399.0 0.1 0.1 0.4 TRBC2 TCRBC2 ENSG00000211772 "T cell receptor beta constant 2" 7 142801041-142802748 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 115.8;lymphoid tissue: 190.2" "Group enriched" "Detected in many" 4 "B-cells: 164.7;dendritic cells: 358.8;NK-cells: 264.7;T-cells: 498.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "T-reg: 76.0" "Lineage enriched" "Detected in many" 7 "T-cells: 76.0" "Cell line enriched" "Detected in some" 45 "MOLT-4: 277.9" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "prognostic favorable (8.04e-5)" "prognostic favorable (1.80e-4)" "unprognostic (4.19e-3)" "prognostic favorable (3.42e-8)" "unprognostic (5.53e-2)" "prognostic favorable (6.58e-5)" "unprognostic (3.21e-2)" "unprognostic (1.30e-2)" "prognostic favorable (2.81e-4)" "unprognostic (7.53e-3)" "unprognostic (5.96e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.90e-7)" "unprognostic (2.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.30e-2)" "unprognostic (4.09e-3)" 18.9 3.1 0.4 3.9 0.3 1.5 8.6 0.1 1.2 11.9 0.1 21.2 1.7 8.7 0.0 14.6 15.7 2.2 4.9 0.3 0.0 9.6 12.7 32.3 8.6 0.2 0.3 18.3 3.5 0.1 4.0 0.0 0.2 14.2 2.7 0.0 7.9 0.1 3.3 6.5 115.8 0.5 0.1 190.2 16.9 8.7 0.3 109.2 16.4 1.2 10.9 14.0 12.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 3.5 0.0 0.0 0.0 0.0 277.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.9 0.0 0.0 14.4 0.0 35.0 8.1 47.6 47.3 0.3 7.7 46.6 40.3 2.0 10.5 0.1 0.0 76.0 42.4 0.4 0.3 0.1 1.2 0.3 0.0 0.2 0.3 0.2 0.1 0.3 0.1 8.3 9.6 52.4 0.0 164.7 0.0 0.3 0.0 1.8 0.1 6.2 9.7 4.8 5.7 3.7 1.8 0.0 0.4 358.8 1.4 0.0 2.9 1.0 1.1 0.8 4.0 0.0 16.6 0.0 1.3 0.1 10.8 8.6 0.9 20.2 0.0 15.0 1.6 0.4 0.0 0.0 0.8 0.0 9.0 0.0 4.2 63.6 18.9 0.0 0.0 19.0 15.6 264.7 0.0 0.0 20.1 0.1 70.3 30.6 0.4 0.1 2.2 2.9 0.4 65.7 4.2 12.4 0.1 0.8 1.3 0.0 0.3 498.0 1.4 0.9 0.2 TRBV19 "TCRBV17S1A1T, TCRBV19S1" ENSG00000211746 "T cell receptor beta variable 19" A0A075B6N1 7 142618849-142619532 "Predicted intracellular proteins, T-cell receptor genes" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 53.4" "Cell type enriched" "Detected in some" 5 "T-cells: 11.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 50.8;memory CD8 T-cell: 40.2;naive CD4 T-cell: 71.1;naive CD8 T-cell: 53.5;T-reg: 88.5" "Lineage enriched" "Detected in single" 191 "T-cells: 88.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (3.62e-3)" "unprognostic (8.91e-4)" "unprognostic (1.14e-2)" "unprognostic (5.81e-3)" "unprognostic (2.38e-2)" "unprognostic (2.29e-4)" "unprognostic (3.96e-3)" "unprognostic (3.62e-3)" "unprognostic (4.51e-3)" "unprognostic (1.14e-2)" "unprognostic (2.07e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.59e-4)" "unprognostic (9.78e-2)" "unprognostic (4.14e-2)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" 0.6 0.1 0.0 5.7 0.0 0.7 0.7 0.1 0.3 0.8 0.0 1.2 0.5 0.5 0.0 0.4 0.3 3.7 0.1 0.1 0.0 0.2 0.7 1.1 28.5 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.1 0.4 2.1 0.0 0.2 0.3 0.1 0.4 3.0 0.2 0.0 3.8 2.9 0.1 0.1 53.4 0.5 0.2 1.9 0.5 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 1.4 0.1 13.5 0.4 50.8 40.2 0.1 0.0 71.1 53.5 0.4 0.1 0.2 0.0 88.5 15.5 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 TRGC2 "TCRGC2, TRGC2(2X), TRGC2(3X)" ENSG00000227191 "T cell receptor gamma constant 2" 7 38239580-38249572 "Predicted membrane proteins, T-cell receptor genes" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "bone marrow: 30.5;lymphoid tissue: 34.6;prostate: 23.7" "Group enriched" "Detected in some" 7 "dendritic cells: 149.1;NK-cells: 90.6;T-cells: 122.0" "Cancer enriched" "Detected in many" 18 "prostate cancer: 26.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 720.5" "Lineage enriched" "Detected in many" 5 "T-cells: 720.5" "Cell line enhanced" "Detected in some" "HL-60: 11.4;JURKAT: 36.6;NB-4: 29.9;SK-BR-3: 9.8;U-937: 53.9" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "unprognostic (2.79e-3)" "prognostic favorable (1.06e-5)" "unprognostic (1.62e-4)" "unprognostic (3.52e-5)" "unprognostic (3.34e-1)" "unprognostic (1.46e-3)" "unprognostic (8.79e-4)" "unprognostic (4.60e-2)" "unprognostic (1.10e-2)" "unprognostic (1.91e-3)" "unprognostic (1.12e-1)" "unprognostic (3.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (2.92e-1)" "unprognostic (1.77e-1)" "unprognostic (5.91e-3)" 3.6 1.1 8.8 5.1 9.0 30.5 1.8 8.6 19.6 1.5 7.1 3.5 4.5 1.3 3.2 1.1 2.2 3.9 0.9 8.4 8.5 1.6 3.6 9.7 17.5 9.6 8.9 0.5 0.8 0.2 1.0 0.5 9.2 23.7 4.0 0.1 1.8 0.8 0.4 0.6 8.0 1.0 9.3 29.7 3.8 2.2 10.2 34.6 2.1 0.1 7.0 3.4 2.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 3.7 1.2 29.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 53.9 0.0 1.1 1.3 1.4 720.5 1.2 287.4 0.6 64.8 341.6 1.0 0.3 13.5 212.9 4.9 149.7 1.0 1.2 1.3 167.5 8.8 9.0 8.6 19.6 8.4 8.5 9.6 8.9 9.2 9.3 10.2 9.5 1.2 0.0 2.4 0.0 2.4 0.0 0.2 0.0 0.0 0.0 1.0 1.3 0.7 1.5 0.6 0.0 0.0 0.0 149.1 0.3 0.0 0.2 15.5 0.2 0.1 0.8 0.0 6.6 0.0 0.0 0.0 0.4 2.6 0.2 0.0 0.2 3.9 1.0 0.0 0.0 0.0 0.5 0.0 3.5 0.0 6.7 0.0 2.8 0.0 0.0 10.6 0.0 90.6 0.0 0.0 0.0 0.0 0.4 14.2 2.8 0.0 0.5 0.0 0.0 0.0 0.2 1.3 0.8 0.2 0.3 0.0 0.3 122.0 0.0 0.2 0.3 TRIM2 "CMT2R, KIAA0517, RNF86" ENSG00000109654 "Tripartite motif containing 2" Q9C040 4 153152163-153339319 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 116.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1132.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD4 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 47.0;SK-MEL-30: 46.8" "HPA035853, HPA035854" Supported Uncertain Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Centrosome "HPA035853: AB_10669533, HPA035854: AB_10669659" "unprognostic (8.94e-2)" "unprognostic (7.89e-2)" "unprognostic (6.21e-3)" "unprognostic (7.51e-3)" "unprognostic (2.07e-2)" "unprognostic (2.32e-1)" "unprognostic (1.16e-2)" "unprognostic (2.30e-3)" "unprognostic (5.30e-2)" "unprognostic (6.77e-2)" "unprognostic (1.93e-2)" "unprognostic (1.42e-2)" "prognostic favorable (6.58e-14)" "unprognostic (5.89e-2)" "unprognostic (1.17e-2)" "unprognostic (4.19e-2)" "unprognostic (4.13e-2)" 5.8 11.8 29.5 4.8 64.4 0.1 11.8 38.6 46.2 23.6 0.0 21.6 17.4 9.9 8.0 10.7 15.2 12.6 8.4 48.0 34.8 24.2 7.9 7.2 2.2 40.1 33.2 12.8 12.7 1.0 21.6 2.5 56.3 13.1 19.3 19.4 42.9 13.4 2.1 7.1 17.3 7.0 35.3 10.6 27.4 1.9 37.9 2.9 50.6 3.0 3.9 12.0 11.5 116.2 10.2 0.2 47.0 24.2 22.0 27.2 0.5 12.7 15.4 3.6 4.5 4.1 0.2 0.1 7.7 21.7 8.5 6.4 24.7 4.7 3.2 0.0 5.4 0.1 4.6 0.5 24.7 0.1 0.1 13.5 2.3 5.4 4.7 12.9 3.4 0.4 0.2 0.0 4.9 0.4 2.4 0.1 37.4 27.5 8.8 1.0 9.4 0.0 37.0 11.8 14.5 27.3 4.4 2.7 46.8 6.9 1.7 0.5 2.8 12.7 3.0 10.8 3.9 0.0 0.0 0.1 20.9 0.0 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 29.5 64.4 38.6 46.2 48.0 34.8 40.1 33.2 56.3 35.3 37.9 116.2 11.2 6.4 33.7 189.0 2.6 7.0 15.3 40.2 9.1 67.7 40.5 29.1 39.6 17.2 82.1 58.8 29.2 2.0 0.7 59.4 101.8 9.6 3.3 113.3 16.3 17.3 62.3 0.4 266.4 26.1 0.5 22.0 80.0 95.6 1.3 4.8 21.0 12.4 1.4 111.0 211.2 64.1 54.9 0.8 7.7 2.4 29.5 2.2 64.0 21.5 3.2 86.9 0.0 237.2 1132.8 22.5 41.4 32.7 1.5 17.8 62.9 14.7 106.0 23.4 26.3 14.7 16.2 0.4 1.3 5.0 4.0 0.7 2.8 8.7 90.8 33.7 TRIM58 BIA2 ENSG00000162722 "Tripartite motif containing 58" Q8NG06 1 247857187-247880138 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 32.2;thyroid gland: 15.2" "Cell type enriched" "Detected in many" 23 "Erythroid cells: 456.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.3;HEL: 40.7;K-562: 21.8;PC-3: 37.0;U-2 OS: 29.0;WM-115: 42.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA023637 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA023637: AB_1858309" "unprognostic (3.85e-1)" "unprognostic (5.24e-3)" "unprognostic (7.00e-2)" "unprognostic (6.52e-4)" "unprognostic (1.46e-1)" "unprognostic (3.47e-2)" "unprognostic (1.10e-1)" "unprognostic (4.14e-5)" "unprognostic (3.59e-1)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (5.00e-2)" "unprognostic (3.31e-1)" "unprognostic (1.08e-2)" "unprognostic (3.34e-1)" "unprognostic (1.00e-2)" "unprognostic (2.57e-2)" 0.5 0.6 0.7 0.6 0.5 32.2 0.5 0.1 1.0 0.4 0.0 1.1 0.1 0.2 0.1 0.1 1.3 0.3 0.2 0.6 2.9 0.2 0.2 1.3 0.2 3.2 4.1 0.0 0.2 0.1 0.2 5.8 4.3 1.5 0.9 0.6 0.3 0.2 0.2 0.9 0.3 0.6 1.3 2.4 0.4 2.7 3.1 0.3 15.2 1.6 0.1 0.2 0.2 0.9 0.0 0.0 0.0 0.0 0.7 2.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.4 1.7 18.3 0.0 0.0 0.0 1.3 40.7 0.0 0.0 0.0 5.5 2.4 0.0 0.0 0.2 0.0 0.0 0.0 1.4 21.8 0.1 0.0 0.0 0.2 0.3 2.7 0.0 37.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.2 4.7 0.0 0.0 29.0 0.0 0.0 6.3 0.0 0.0 0.0 13.0 42.1 0.7 0.1 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.3 0.1 0.1 0.0 0.6 0.7 0.5 0.1 1.0 0.6 2.9 3.2 4.1 4.3 1.3 3.1 0.9 0.6 3.2 3.0 0.3 1.7 1.0 1.4 0.0 0.6 3.4 1.1 0.3 0.5 0.0 5.6 1.8 12.5 3.3 0.4 0.8 0.0 0.1 4.3 2.5 0.7 1.7 1.2 456.4 3.7 0.0 4.6 3.0 0.0 2.1 8.2 0.4 1.8 0.1 2.4 0.0 1.8 0.4 0.0 3.2 1.4 1.2 0.9 19.4 1.8 0.0 1.0 2.7 2.1 0.5 0.3 0.2 0.7 0.7 0.3 4.0 0.0 0.2 3.7 3.7 0.0 0.9 0.7 2.8 9.7 0.1 0.9 4.9 1.7 0.3 0.8 0.8 TSN "BCLF-1, REHF-1, TRSLN" ENSG00000211460 Translin Q15631 2 121737103-121767853 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059561 Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA059561: AB_2684063" "unprognostic (3.15e-2)" "unprognostic (1.83e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (7.05e-4)" "unprognostic (7.13e-3)" "unprognostic (3.12e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (2.32e-2)" "unprognostic (7.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.04e-2)" "unprognostic (3.42e-2)" "unprognostic (3.18e-1)" 16.2 16.9 20.9 13.5 21.9 47.8 25.4 22.7 28.4 17.4 18.9 23.3 16.9 15.8 17.9 16.6 14.2 13.2 19.5 21.0 23.6 24.4 22.9 14.3 19.1 21.3 22.4 16.7 18.4 21.7 13.1 10.8 22.3 14.5 18.8 16.6 14.9 17.2 31.6 19.3 14.6 14.2 21.4 14.7 15.0 26.2 22.0 24.1 17.2 31.0 18.2 15.6 12.8 23.8 56.2 24.8 38.4 34.1 35.0 27.8 21.1 45.6 43.2 50.3 48.4 71.1 32.3 81.7 51.9 45.4 30.1 27.0 55.0 46.6 69.8 43.2 44.3 48.0 33.0 68.3 40.0 69.3 32.5 24.2 51.3 56.3 38.7 23.0 43.2 40.0 72.9 39.4 47.4 30.5 38.2 77.5 46.6 32.8 47.2 67.6 43.1 59.3 63.7 36.0 48.9 30.6 31.4 46.6 61.2 29.2 29.3 54.1 30.8 36.2 56.4 22.9 45.1 33.8 97.0 85.4 40.3 46.8 45.6 27.6 29.8 28.6 22.5 27.9 26.9 27.4 23.4 19.8 27.4 21.0 26.5 22.9 9.3 26.9 24.3 20.1 25.6 28.8 20.9 21.9 22.7 28.4 21.0 23.6 21.3 22.4 22.3 21.4 22.0 23.8 34.7 32.1 24.4 15.0 37.5 39.1 34.4 49.1 23.3 32.1 38.2 27.6 34.7 42.9 36.9 42.3 22.9 34.9 34.3 22.3 43.0 64.4 80.0 24.9 29.7 42.7 19.9 34.7 19.8 60.0 33.3 32.5 15.8 23.9 40.0 36.0 58.5 44.4 35.2 16.8 19.8 27.7 57.0 35.6 34.9 19.8 36.4 29.8 67.6 15.0 45.4 88.7 44.3 29.1 33.5 45.4 22.2 31.2 25.4 34.7 24.4 58.7 33.0 29.5 26.3 39.9 81.8 152.8 96.6 36.7 43.9 28.5 36.8 38.5 37.9 28.8 TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "glioma: 54.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 139.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: AB_2683447" "unprognostic (2.66e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "unprognostic (1.82e-1)" "unprognostic (8.96e-3)" "prognostic unfavorable (1.09e-4)" "unprognostic (4.31e-3)" "unprognostic (1.19e-1)" "unprognostic (6.51e-3)" "unprognostic (5.31e-2)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "prognostic favorable (9.91e-5)" "unprognostic (1.68e-1)" "unprognostic (1.59e-1)" "unprognostic (6.32e-2)" "unprognostic (1.58e-1)" 24.5 29.7 9.0 11.2 10.8 5.5 23.1 10.8 15.6 26.2 11.8 20.5 16.4 26.2 13.2 20.4 25.8 20.9 26.7 9.5 10.3 26.7 20.9 22.8 11.8 11.2 10.2 25.6 25.2 32.7 24.4 12.5 11.0 22.1 10.7 29.7 25.6 13.5 21.0 18.6 18.5 8.4 11.1 20.8 23.0 8.0 9.9 9.8 30.2 21.2 8.7 21.0 20.1 13.0 9.5 23.4 21.1 5.4 44.3 24.0 13.5 15.8 11.7 4.6 5.1 16.7 46.4 7.6 32.7 29.0 9.4 17.5 5.7 26.7 10.7 23.1 15.4 10.7 18.7 6.6 45.2 10.6 17.9 29.6 30.2 13.7 30.3 22.1 14.6 4.6 7.5 19.9 19.6 19.4 9.2 5.9 4.3 18.3 7.0 10.5 139.8 20.0 15.7 19.0 6.6 16.7 15.6 21.3 10.5 4.5 41.1 15.8 27.6 11.3 9.5 5.6 7.4 28.9 8.1 4.1 32.7 6.3 19.2 25.4 26.3 16.4 35.8 28.6 34.8 31.1 28.5 30.7 27.6 31.0 28.3 26.2 5.8 35.4 42.0 58.3 22.1 33.0 9.0 10.8 10.8 15.6 9.5 10.3 11.2 10.2 11.0 11.1 9.9 13.0 37.1 48.1 32.4 8.1 23.8 11.2 46.4 37.4 22.2 43.2 32.0 27.4 5.1 20.0 31.4 31.3 41.7 20.9 29.8 19.9 9.8 37.6 1.2 18.5 32.5 26.7 26.5 8.2 9.1 39.0 15.2 31.7 11.7 20.4 45.0 28.9 22.1 21.6 22.4 21.9 9.1 21.6 32.6 18.0 16.4 1.8 25.7 24.2 32.0 8.4 21.6 62.7 35.0 11.1 13.3 37.6 20.3 17.3 18.4 30.5 30.6 18.1 27.9 60.4 19.7 22.3 31.9 9.2 7.7 16.1 12.6 24.5 20.4 35.3 19.4 31.8 TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 422.5;Granulosa cells: 684.8;Late spermatids: 1708.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 6 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "NTERA-2: 121.7;RT4: 153.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" 29.6 18.2 7.2 4.9 7.5 0.6 34.2 7.2 8.9 26.9 26.8 40.0 19.7 20.5 14.8 46.8 39.5 16.7 8.6 7.4 9.0 36.5 70.2 11.3 3.0 8.7 9.3 53.4 20.2 34.7 36.9 20.0 8.2 18.9 33.1 6.2 52.6 10.3 4.6 9.7 18.5 7.2 8.9 8.7 14.8 74.9 9.6 4.2 19.3 5.3 6.8 32.2 24.1 12.0 24.8 23.0 80.6 42.2 28.7 16.6 30.4 12.9 17.3 20.3 47.6 54.9 37.7 0.0 53.3 12.2 16.9 19.9 0.3 19.7 25.8 0.1 33.3 3.8 14.9 62.0 17.1 0.1 2.5 30.2 9.3 19.5 6.6 34.4 49.3 0.0 0.0 0.1 21.7 19.8 0.1 0.3 121.7 35.4 18.4 0.0 35.5 0.0 33.0 153.5 4.7 20.3 11.6 10.0 18.5 61.9 16.6 3.3 12.7 16.0 24.4 24.3 8.6 0.1 0.2 0.3 13.4 0.0 11.5 0.3 0.0 0.1 0.3 0.0 1.1 0.1 0.8 0.3 0.0 0.1 2.1 1.2 0.3 0.1 0.1 0.1 0.0 0.3 7.2 7.5 7.2 8.9 7.4 9.0 8.7 9.3 8.2 8.9 9.6 12.0 147.0 3.2 10.1 14.4 2.3 7.1 41.0 75.7 29.0 0.6 72.5 46.1 8.2 50.1 89.4 93.8 0.0 28.7 1.1 94.9 23.5 80.3 422.5 54.0 21.4 37.4 33.6 4.8 0.9 12.6 40.7 25.6 21.9 19.2 0.0 684.8 47.5 104.0 4.5 0.0 0.8 47.9 193.3 10.2 3.1 1708.3 32.9 3.1 10.6 1.0 1.0 48.2 0.0 9.5 0.4 18.7 55.5 35.7 0.3 33.0 43.5 43.8 193.9 1.9 19.7 17.1 43.1 20.9 32.4 23.3 5.4 13.5 2.5 49.4 94.3 89.7 TSPYL1 TSPYL ENSG00000189241 "TSPY like 1" Q9H0U9 6 116267760-116279930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031970 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 38: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli" "HPA031970: AB_2674092" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (6.11e-2)" "unprognostic (9.99e-2)" "unprognostic (1.70e-1)" "unprognostic (3.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "unprognostic (2.76e-1)" "unprognostic (9.18e-3)" "prognostic favorable (5.40e-4)" "unprognostic (5.12e-1)" "prognostic favorable (1.48e-13)" "unprognostic (1.61e-1)" "unprognostic (1.81e-1)" "unprognostic (2.34e-2)" "unprognostic (2.47e-1)" 26.5 73.8 51.1 17.1 56.4 34.4 23.4 35.2 78.2 22.5 25.5 30.8 24.4 28.4 33.0 34.0 31.4 20.5 43.3 64.9 38.1 50.4 40.9 21.4 21.4 25.9 22.2 34.9 33.3 63.9 40.1 16.0 26.0 42.0 17.7 26.1 30.2 33.9 114.9 29.4 30.0 24.3 17.1 29.5 35.5 28.9 34.6 22.3 39.6 91.9 25.6 31.4 22.7 44.5 22.2 21.5 27.3 50.3 47.2 30.9 22.7 35.2 34.7 31.3 35.8 27.7 15.9 47.3 43.0 40.8 28.2 38.5 21.6 59.8 33.2 19.4 56.0 19.1 29.9 50.8 29.8 31.9 11.2 36.2 46.0 32.5 31.2 32.9 30.3 20.7 34.3 36.1 44.2 48.9 21.5 18.9 13.6 21.3 19.8 19.1 23.5 26.3 54.9 42.9 23.7 23.6 29.2 38.8 18.0 30.6 51.0 39.1 37.3 21.2 18.7 17.2 38.7 19.8 22.7 25.2 35.1 20.3 14.1 121.0 30.1 51.5 40.5 51.0 61.4 46.4 52.4 45.4 26.1 52.2 51.1 50.0 24.1 33.2 57.7 44.9 44.8 34.0 51.1 56.4 35.2 78.2 64.9 38.1 25.9 22.2 26.0 17.1 34.6 44.5 29.4 35.3 45.9 15.7 65.2 166.1 100.6 37.6 70.6 81.0 91.7 47.5 100.0 61.5 40.5 104.8 27.1 54.8 54.2 49.3 154.6 40.8 33.0 40.5 42.0 40.4 74.6 49.7 65.4 43.9 25.5 63.1 41.3 34.9 31.7 67.5 73.9 81.3 42.4 38.7 50.5 59.3 46.8 82.1 116.0 20.2 75.5 40.2 87.2 22.5 38.3 82.6 42.2 15.6 20.2 48.8 52.5 95.5 24.1 77.0 60.3 218.9 41.4 58.1 131.5 87.6 63.5 61.9 39.8 55.5 162.0 59.7 69.1 101.3 70.2 75.8 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TSTD1 KAT ENSG00000215845 "Thiosulfate sulfurtransferase like domain containing 1" Q8NFU3 1 161037631-161038977 "Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 684.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 205.3;OE19: 215.1;SK-BR-3: 284.0;T-47d: 274.9;U-266/70: 315.4;U-266/84: 243.2" "Region enriched" "Detected in some" 4 "olfactory bulb: 6.6" "Low region specificity" "Detected in all" "HPA006518, HPA006655" Approved Approved "Cytosol,Cytoplasmic bodies" NA NA 57000 "Cluster 37: B-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cytosol, Cytoplasmic bodies" "HPA006518: AB_2667608, HPA006655: AB_10600919" "unprognostic (6.10e-2)" "unprognostic (4.70e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" "unprognostic (5.77e-2)" "unprognostic (1.63e-1)" "unprognostic (6.56e-2)" "unprognostic (2.51e-3)" "unprognostic (2.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "unprognostic (1.13e-1)" "unprognostic (4.64e-2)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (8.57e-3)" "unprognostic (8.88e-3)" 33.8 72.1 28.3 25.8 31.4 48.3 73.6 19.8 40.3 31.4 34.6 60.3 40.4 10.4 101.5 91.3 69.2 18.9 55.4 28.2 28.0 125.3 74.7 47.4 52.8 21.2 23.4 55.1 93.5 167.2 119.2 13.2 23.2 98.6 40.8 11.4 175.7 43.5 38.7 79.6 50.5 8.5 20.8 39.7 61.3 35.6 27.3 59.5 140.0 18.6 51.2 29.9 46.4 24.9 119.8 1.6 0.3 0.6 0.0 0.0 2.1 0.2 0.0 0.2 0.0 11.1 112.5 25.0 67.9 0.0 0.0 107.2 0.1 46.4 0.0 98.4 84.9 13.3 43.2 0.0 12.2 43.7 0.9 0.6 28.2 0.0 4.8 0.1 15.6 100.8 0.4 130.8 12.8 205.3 118.6 0.6 0.7 215.1 0.3 38.7 0.0 184.8 98.0 32.8 67.5 37.2 0.0 284.0 0.9 54.0 274.9 0.6 0.5 0.0 41.5 0.6 4.8 315.4 243.2 26.3 0.3 0.2 0.4 438.2 24.2 357.7 226.5 72.0 218.8 530.9 296.2 252.0 72.6 506.1 333.3 282.1 337.5 306.5 104.8 203.9 410.8 220.6 28.3 31.4 19.8 40.3 28.2 28.0 21.2 23.4 23.2 20.8 27.3 24.9 6.5 253.2 228.8 1.0 170.3 86.3 307.5 331.1 160.5 16.2 443.9 457.1 68.4 223.1 259.0 367.8 27.1 271.5 101.2 478.1 684.8 169.7 16.3 336.9 29.2 14.0 218.5 29.0 5.8 151.5 112.7 35.8 59.1 201.2 124.7 88.7 10.8 149.3 72.3 3.3 1.9 418.1 402.8 18.7 116.2 25.1 8.4 40.7 151.2 1.9 178.3 73.0 206.0 1.0 0.7 131.5 383.6 9.8 110.5 386.2 426.6 665.8 615.1 31.8 19.7 99.5 37.7 73.3 44.4 199.6 135.8 151.0 149.3 31.7 267.0 384.9 TTC1 TPR1 ENSG00000113312 "Tetratricopeptide repeat domain 1" Q99614 5 160009113-160065543 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036557, HPA057502" Approved Enhanced Cytosol NA NA 17000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA036557: AB_10670112, HPA057502: AB_2683450" "unprognostic (4.34e-3)" "unprognostic (2.26e-2)" "unprognostic (3.05e-2)" "unprognostic (7.38e-2)" "unprognostic (6.62e-2)" "unprognostic (8.13e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.29e-2)" "unprognostic (2.38e-1)" "unprognostic (5.50e-2)" "unprognostic (2.31e-1)" "unprognostic (2.35e-1)" "unprognostic (1.08e-3)" "unprognostic (2.04e-2)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (6.16e-2)" 37.0 46.5 77.6 35.6 79.7 26.2 39.4 84.2 111.7 31.5 71.2 44.5 27.3 32.2 58.1 37.4 32.2 26.2 59.9 79.4 83.1 49.5 45.5 33.0 47.8 90.6 85.4 32.6 27.4 45.1 29.8 35.5 88.7 33.4 45.4 42.9 39.4 37.2 91.2 34.8 30.9 41.8 80.3 36.6 34.6 33.8 83.8 48.7 35.7 77.0 55.9 35.7 27.6 84.1 83.2 85.1 62.2 104.4 71.9 51.6 70.5 90.8 80.4 97.7 115.6 120.2 94.0 84.5 172.7 78.2 132.9 63.9 83.5 124.7 156.6 157.7 88.4 75.9 63.0 87.3 102.0 127.2 61.2 48.7 81.0 86.5 71.8 71.8 118.8 74.2 73.6 81.7 112.3 65.0 92.8 99.8 70.7 67.3 85.8 88.4 87.0 93.6 124.2 76.8 51.2 57.7 63.1 74.4 175.1 58.3 117.6 121.5 84.4 64.8 55.8 58.5 141.9 58.4 114.8 82.3 89.6 143.3 85.9 109.8 72.8 105.7 57.6 80.9 73.4 92.6 68.3 68.0 73.5 86.0 62.5 69.1 103.0 87.7 80.6 65.4 90.2 113.1 77.6 79.7 84.2 111.7 79.4 83.1 90.6 85.4 88.7 80.3 83.8 84.1 48.6 67.3 50.8 20.9 55.0 47.0 33.6 89.2 28.5 38.4 40.4 47.0 237.0 40.0 67.4 46.0 20.9 108.7 36.0 58.0 162.4 114.2 115.3 62.8 46.5 61.3 35.3 89.2 54.0 106.5 77.9 57.4 23.4 54.8 83.4 41.3 52.1 72.8 90.0 35.3 47.6 51.4 83.4 48.1 34.7 39.9 46.9 52.4 28.4 23.4 70.1 99.1 68.0 43.7 57.0 98.5 54.7 63.9 42.9 37.6 53.7 144.9 89.4 50.2 59.2 55.7 59.2 142.9 101.5 37.8 47.3 99.9 50.8 53.6 53.7 21.9 TTC19 "FLJ20343, MGC19520" ENSG00000011295 "Tetratricopeptide repeat domain 19" Q6DKK2 17 15999784-16045015 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023010, HPA052380" Enhanced Enhanced Mitochondria "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA023010: AB_1858429, HPA052380: AB_2681806" "unprognostic (1.04e-2)" "unprognostic (4.90e-3)" "unprognostic (2.87e-2)" "unprognostic (4.80e-3)" "unprognostic (8.09e-2)" "unprognostic (2.86e-1)" "unprognostic (1.06e-2)" "unprognostic (2.84e-2)" "unprognostic (8.34e-2)" "unprognostic (1.72e-2)" "unprognostic (2.30e-3)" "unprognostic (5.14e-2)" "prognostic favorable (5.67e-4)" "unprognostic (1.31e-1)" "unprognostic (3.22e-1)" "unprognostic (4.85e-2)" "unprognostic (2.24e-1)" 6.6 11.4 8.1 3.8 7.8 11.2 7.5 19.4 11.6 6.9 8.4 8.0 10.3 6.9 5.2 6.8 5.8 5.2 8.6 8.8 9.6 8.7 7.7 6.6 4.6 7.9 7.4 6.9 12.4 11.2 8.0 5.8 7.9 6.8 5.7 9.9 9.1 4.2 8.8 9.5 9.8 3.8 6.3 4.5 8.4 3.6 8.0 3.9 10.6 4.4 3.3 6.3 6.7 10.5 7.0 4.1 7.6 12.1 6.4 5.6 4.0 3.1 4.6 3.1 3.8 6.5 12.8 8.9 9.8 4.3 4.6 9.1 9.9 8.3 3.8 12.5 10.2 8.2 9.2 6.3 9.1 9.3 11.6 5.6 7.0 2.6 11.4 9.6 7.1 12.4 4.6 7.7 6.8 7.6 7.5 6.8 10.0 11.8 3.0 7.8 8.0 8.2 11.6 10.5 6.6 5.5 7.6 9.8 16.6 24.6 6.9 4.6 13.1 4.2 1.2 6.1 7.5 4.8 1.5 4.2 9.8 9.8 9.5 5.2 0.7 1.8 0.7 0.7 1.2 0.9 0.9 1.2 0.7 1.1 1.0 1.3 0.7 0.6 0.7 1.1 1.0 0.4 8.1 7.8 19.4 11.6 8.8 9.6 7.9 7.4 7.9 6.3 8.0 10.5 51.0 41.7 38.6 69.5 60.8 105.3 83.5 30.8 70.6 147.8 65.1 47.9 34.8 42.9 35.4 46.0 143.9 75.7 62.8 59.7 70.5 50.0 59.4 49.4 41.5 60.3 45.6 32.4 115.1 41.2 41.9 34.2 43.8 67.9 31.1 46.8 42.8 36.0 25.6 129.5 100.9 52.3 26.4 25.8 76.7 7.2 41.0 46.5 55.2 35.6 34.8 73.9 70.0 54.3 57.8 47.7 57.9 33.4 34.5 89.1 75.4 47.1 26.5 180.4 46.0 56.5 40.2 30.2 31.1 56.9 116.8 65.5 68.9 69.9 63.3 72.7 TTC8 "BBS8, RP51" ENSG00000165533 "Tetratricopeptide repeat domain 8" Q8TAM2 14 88824153-88881078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 66.8;Theca cells: 69.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.8" "Cell line enhanced" "Detected in all" "SH-SY5Y: 118.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.19e-2)" "unprognostic (1.08e-1)" "unprognostic (5.47e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.49e-1)" "unprognostic (7.10e-2)" "unprognostic (5.00e-3)" "unprognostic (1.54e-1)" "unprognostic (2.19e-1)" "prognostic favorable (7.77e-4)" "unprognostic (3.54e-2)" "unprognostic (2.51e-1)" "prognostic favorable (4.89e-4)" "unprognostic (1.65e-2)" "unprognostic (1.84e-1)" "unprognostic (2.44e-1)" "unprognostic (3.80e-2)" 8.3 38.9 13.9 6.6 14.6 9.3 18.6 11.8 14.2 15.5 20.4 9.4 6.0 13.5 35.9 13.0 23.2 15.5 11.5 14.9 19.3 13.6 13.2 8.9 4.3 14.0 14.4 68.9 12.0 22.5 22.4 6.8 12.7 23.6 9.9 37.4 10.0 18.6 2.6 8.8 5.8 14.4 13.3 6.8 8.4 23.7 16.5 5.9 37.1 4.2 5.0 16.4 5.0 13.4 19.8 28.1 16.7 16.2 35.1 43.5 14.0 24.0 37.6 31.8 21.5 7.9 37.2 8.7 20.6 30.3 19.3 28.5 18.1 19.4 32.2 6.6 7.3 5.5 9.1 11.1 25.4 10.6 1.9 27.3 23.9 23.0 19.9 30.4 19.3 11.6 20.5 9.8 27.3 33.9 10.9 10.2 8.9 10.3 27.0 3.3 23.0 5.2 31.3 30.6 19.6 118.5 38.0 21.3 22.4 11.5 52.6 8.3 11.7 22.6 11.9 20.2 16.6 1.2 6.8 3.8 33.3 2.8 9.9 13.8 0.7 3.8 0.4 0.9 0.6 0.4 0.5 0.5 1.9 2.2 0.2 0.4 0.7 1.7 1.5 0.7 0.0 0.5 13.9 14.6 11.8 14.2 14.9 19.3 14.0 14.4 12.7 13.3 16.5 13.4 3.7 3.2 9.0 38.8 2.1 8.8 8.0 12.3 19.4 17.0 11.7 9.1 6.0 10.0 11.2 9.2 39.6 10.2 0.6 4.3 13.7 13.5 8.1 24.1 10.6 4.9 10.8 4.8 51.1 6.2 9.7 12.8 6.1 11.7 0.0 66.8 5.3 8.0 6.7 20.2 53.4 6.1 6.1 3.5 6.6 7.4 19.6 4.4 7.2 14.0 0.4 12.5 1.0 51.3 21.3 7.8 2.4 25.2 3.7 4.9 2.3 15.5 28.3 41.7 19.7 5.8 12.2 14.6 6.9 8.3 6.5 1.8 1.2 69.0 6.6 4.7 TUNAR "HI-LNC78, LINC00617, TUNA" ENSG00000250366 "TCL1 upstream neural differentiation-associated RNA" 14 95876392-95925663 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 42.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.1;Endometrial ciliated cells: 11.5;Endometrial stromal cells: 8.9;Excitatory neurons: 4.6;Glandular and luminal cells: 16.8;Spermatogonia: 3.5" "Cancer enhanced" "Detected in many" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 16.3;HAP1: 7.0;NTERA-2: 11.8;SCLC-21H: 16.1;SuSa: 4.6" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "unprognostic (1.28e-3)" "unprognostic (3.94e-1)" "unprognostic (4.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "prognostic favorable (1.55e-4)" "unprognostic (5.33e-2)" "unprognostic (2.92e-2)" "unprognostic (1.18e-1)" 0.0 0.1 6.3 0.1 42.5 0.3 0.4 5.6 10.8 0.3 0.0 0.0 0.1 6.5 0.1 0.0 8.5 0.1 0.0 9.5 9.6 0.2 0.0 0.0 0.3 30.8 12.0 0.1 2.7 0.0 1.2 0.0 30.5 0.0 0.0 8.5 0.0 3.5 0.0 0.1 0.0 0.0 11.6 0.1 0.5 1.3 23.0 0.1 1.1 0.0 0.2 0.0 0.0 3.9 0.0 0.1 16.3 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 7.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 11.8 0.0 0.1 0.7 0.0 0.0 0.4 0.1 16.1 1.3 0.0 0.1 0.0 4.6 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 42.5 5.6 10.8 9.5 9.6 30.8 12.0 30.5 11.6 23.0 3.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 1.3 0.0 0.0 0.0 2.8 11.5 8.9 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TVP23B "CGI-148, FAM18B, FAM18B1, YDR084C" ENSG00000171928 "Trans-golgi network vesicle protein 23 homolog B" Q9NYZ1 17 18781111-18806714 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019585, HPA065603" Uncertain Supported "Golgi apparatus" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" "HPA019585: AB_1848385, HPA065603: AB_2685517" "unprognostic (1.91e-1)" "unprognostic (1.58e-1)" "unprognostic (1.05e-1)" "unprognostic (9.32e-3)" "unprognostic (1.13e-2)" "unprognostic (8.51e-2)" "unprognostic (2.37e-1)" "unprognostic (3.32e-2)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (3.54e-1)" "unprognostic (5.27e-1)" "unprognostic (7.78e-2)" "unprognostic (8.55e-2)" 26.4 43.2 11.1 20.0 11.7 19.9 30.3 12.8 15.1 38.2 23.3 25.8 29.9 26.5 40.4 52.3 34.5 30.4 22.8 10.6 13.5 31.0 44.0 20.8 25.4 12.3 13.0 30.1 33.6 47.8 32.7 29.6 13.0 33.5 31.2 32.1 34.3 24.4 17.3 19.3 23.8 21.7 13.1 17.4 40.5 34.9 12.4 20.4 46.9 16.2 31.4 32.7 34.2 13.3 55.0 63.8 23.6 26.2 68.8 60.9 56.1 93.5 75.0 42.8 54.6 37.6 38.7 17.9 33.9 60.3 42.6 74.1 19.2 40.2 63.2 44.3 39.7 17.0 47.1 46.3 48.0 13.0 35.6 31.6 95.7 46.0 67.7 78.7 36.0 12.6 14.0 13.1 62.9 27.6 17.2 18.3 11.0 99.2 25.6 17.4 52.1 23.1 52.7 36.0 13.4 29.9 49.8 32.4 60.4 129.0 46.9 19.7 41.6 32.7 28.1 69.8 57.5 25.9 31.7 9.5 50.2 22.2 68.2 54.4 20.4 44.6 29.7 27.4 40.5 32.1 33.0 32.1 17.3 26.9 34.8 34.8 24.2 32.3 27.1 27.9 26.3 32.1 11.1 11.7 12.8 15.1 10.6 13.5 12.3 13.0 13.0 13.1 12.4 13.3 10.0 12.8 13.2 9.4 29.4 25.2 28.1 70.4 54.7 8.6 16.5 9.7 4.2 10.0 42.4 9.2 10.4 13.3 15.7 8.5 11.7 13.9 8.6 21.7 16.1 12.9 6.1 17.2 8.1 11.6 30.3 19.1 40.2 16.2 22.2 7.1 11.0 10.3 10.0 1.7 8.8 14.6 44.7 10.3 10.7 4.2 16.8 16.0 26.6 11.2 9.1 9.1 17.5 14.1 12.8 16.5 10.7 17.0 62.1 28.5 12.0 14.0 60.0 11.1 13.1 9.0 17.0 50.8 43.0 65.5 30.5 26.1 23.7 8.9 8.6 32.4 TWF1 "A6, PTK9" ENSG00000151239 "Twinfilin actin binding protein 1" Q12792 12 43793723-43806328 "Disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018116 Approved Supported Cytosol NA NA 75000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "HPA018116: AB_1855899" "unprognostic (3.06e-1)" "unprognostic (1.95e-2)" "prognostic favorable (8.29e-4)" "unprognostic (7.39e-3)" "unprognostic (2.35e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (5.19e-2)" "unprognostic (1.13e-2)" "unprognostic (7.30e-2)" "unprognostic (3.11e-3)" "unprognostic (2.51e-1)" "unprognostic (8.48e-2)" "unprognostic (1.03e-1)" "unprognostic (2.19e-1)" "unprognostic (2.95e-1)" "unprognostic (2.62e-1)" 45.2 40.2 27.9 39.0 33.0 46.2 49.4 30.6 38.9 54.8 27.2 65.9 68.7 39.9 48.5 93.8 45.3 48.7 13.1 26.5 32.5 51.2 53.9 24.9 30.5 32.5 30.9 27.1 39.0 39.9 23.9 35.0 32.6 46.0 65.7 32.5 42.5 73.5 5.8 36.7 67.8 46.6 31.8 20.2 46.1 20.1 30.8 24.4 73.1 11.7 34.2 74.6 38.0 37.2 121.3 88.5 45.1 55.5 115.8 132.5 109.3 165.3 136.1 131.7 99.2 143.3 165.2 32.5 150.0 159.6 77.3 79.8 62.6 118.2 186.1 11.3 72.5 30.2 68.6 67.7 93.9 35.0 37.6 91.0 94.4 136.8 152.0 167.5 117.0 16.1 33.4 35.9 207.4 64.8 16.8 24.1 27.5 0.0 142.7 14.1 51.1 36.8 175.9 149.1 33.3 50.0 138.2 123.7 121.7 62.8 116.2 34.4 113.0 161.5 107.1 130.8 139.8 31.1 32.9 44.4 148.8 89.0 62.6 10.2 2.6 5.7 5.1 4.1 5.9 6.1 6.0 6.6 4.1 3.0 5.9 6.7 4.4 12.1 4.4 2.7 6.6 3.2 27.9 33.0 30.6 38.9 26.5 32.5 32.5 30.9 32.6 31.8 30.8 37.2 40.7 12.8 33.8 6.2 24.7 41.7 33.3 32.6 42.1 22.7 43.9 30.6 6.0 30.0 40.3 35.0 20.9 41.5 36.2 92.8 41.1 50.9 20.6 70.9 40.3 32.0 44.9 7.8 10.1 79.7 58.0 32.4 53.0 53.6 5.1 27.7 24.3 28.7 26.9 20.2 10.3 45.2 48.8 30.0 20.9 10.8 26.8 24.7 35.6 8.4 17.7 33.5 14.4 10.1 15.7 74.9 77.4 32.0 34.0 57.5 66.3 68.7 53.5 32.9 26.3 25.4 41.7 11.7 22.1 95.0 51.1 85.0 25.8 39.6 61.8 74.9 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Plasma cells: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 141.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" 15.7 14.2 4.5 22.5 5.6 55.4 16.6 7.7 5.9 20.8 16.6 30.0 38.5 15.1 23.6 13.1 16.2 17.3 13.7 5.0 4.9 25.7 44.3 34.9 25.3 4.8 4.8 16.6 26.5 45.1 12.6 17.0 4.8 24.4 29.8 15.3 34.8 14.9 30.1 12.0 32.0 15.6 4.6 22.4 36.1 8.5 4.9 20.6 34.4 14.9 27.9 25.3 11.8 5.0 26.1 17.7 8.2 11.2 21.6 18.0 14.4 25.3 34.5 22.7 29.1 8.8 40.5 65.2 41.6 32.0 30.9 22.9 10.2 21.4 18.5 29.4 13.5 13.9 19.4 43.8 31.7 20.6 27.1 13.7 23.6 25.4 39.9 17.6 28.9 14.6 21.5 81.8 20.2 23.7 16.1 7.9 10.7 18.6 9.1 20.5 16.5 141.9 26.0 13.7 11.5 10.9 49.6 38.2 27.3 9.1 23.4 28.1 30.1 10.5 12.0 49.8 14.7 110.5 64.8 39.5 22.3 25.7 17.9 3.5 2.4 7.7 1.8 1.7 4.5 3.8 3.3 4.1 2.6 4.6 3.2 2.1 0.7 5.6 2.2 2.0 6.8 2.8 4.5 5.6 7.7 5.9 5.0 4.9 4.8 4.8 4.8 4.6 4.9 5.0 16.2 44.8 46.2 21.9 49.2 14.7 24.8 12.9 23.3 16.2 16.1 18.0 9.1 18.6 24.6 18.4 50.1 21.1 27.2 45.8 15.6 20.4 3.1 19.9 14.6 15.2 24.5 6.5 23.0 39.7 29.8 14.0 45.3 28.5 15.2 13.0 15.7 39.3 30.3 23.5 25.5 44.0 8.2 18.1 26.9 1.4 20.2 29.2 23.2 18.7 21.2 16.4 15.5 22.1 18.6 26.1 21.0 13.2 307.9 28.0 37.1 15.2 15.9 23.4 6.6 13.8 16.2 11.6 13.1 17.5 11.8 25.0 25.2 11.3 27.7 32.1 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "dendritic cells: 5.9;Erythroid cells: 3.8;T-cells: 20.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 22.9;memory CD4 T-cell: 28.2;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.2;naive CD8 T-cell: 24.0;T-reg: 27.9" "Lineage enriched" "Detected in many" 12 "T-cells: 32.2" "Group enriched" "Detected in some" 7 "HEL: 23.0;JURKAT: 39.0;MOLT-4: 47.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA035367 Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm "Golgi apparatus" "HPA035367: AB_2732466" "unprognostic (5.14e-4)" "unprognostic (3.91e-4)" "unprognostic (1.57e-2)" "unprognostic (4.10e-5)" "unprognostic (4.33e-2)" "unprognostic (1.85e-6)" "unprognostic (5.54e-4)" "unprognostic (1.46e-3)" "unprognostic (6.17e-4)" "unprognostic (2.47e-3)" "unprognostic (1.94e-2)" "unprognostic (1.81e-1)" "unprognostic (2.37e-6)" "unprognostic (1.65e-1)" "unprognostic (7.96e-2)" "unprognostic (3.24e-2)" "unprognostic (4.17e-2)" 0.4 0.6 0.0 5.2 0.0 2.5 0.2 0.0 0.1 0.5 0.1 0.8 1.6 0.5 0.0 0.4 0.4 2.0 0.4 0.0 0.1 0.4 0.7 1.7 11.1 0.2 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.4 0.9 0.0 0.9 0.1 0.2 0.3 2.4 0.1 0.1 4.4 1.9 0.1 0.0 18.9 0.5 0.1 5.1 1.7 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 23.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 39.0 4.4 0.0 0.0 0.0 47.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 12.9 0.0 22.9 0.1 28.2 24.8 0.0 0.0 32.2 24.0 0.5 2.5 0.1 0.1 27.9 10.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.8 0.4 0.0 0.8 0.0 0.0 0.2 0.3 1.0 0.0 0.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.0 3.8 0.0 0.0 0.0 0.4 1.1 0.5 1.3 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.1 0.6 0.0 0.3 0.0 20.5 0.0 0.0 0.0 UBB "FLJ25987, MGC8385" ENSG00000170315 "Ubiquitin B" P0CG47 17 16380798-16382745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013048, HPA041344, HPA049132" Supported NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "CAB013048: AB_2533002, HPA041344: AB_2677422, HPA049132: AB_2680646" "unprognostic (1.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (3.86e-1)" "unprognostic (9.32e-2)" "unprognostic (1.29e-3)" "unprognostic (2.48e-2)" "unprognostic (5.81e-2)" "unprognostic (2.15e-3)" "unprognostic (2.88e-2)" "unprognostic (1.45e-2)" "prognostic favorable (1.07e-4)" "unprognostic (1.02e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 942.4 1676.7 1564.8 674.6 1589.2 2376.9 770.4 1662.2 2231.7 812.8 1565.4 1065.5 1179.6 788.9 1367.0 656.3 656.8 813.0 1668.3 1644.2 1719.8 1593.6 2982.1 1046.3 1002.7 1672.3 1765.4 726.2 1305.1 1677.7 1373.8 1012.3 1713.9 808.0 1097.8 566.0 1294.6 861.8 2656.6 692.3 1134.0 932.4 1670.6 1078.8 1245.6 1591.8 1597.4 1226.8 1181.5 2162.1 993.0 974.7 689.1 1980.8 1646.5 3022.4 1559.8 1912.1 1530.0 963.9 1131.3 1609.5 2166.2 2855.8 2453.4 2916.5 1270.4 1662.3 2631.3 1916.6 1678.5 1295.4 0.8 1054.2 3076.0 2126.4 2231.3 1649.8 1653.1 2183.7 1022.3 6.6 2162.4 1468.9 1010.2 2183.4 848.2 1486.0 1582.3 1562.2 1888.9 1530.9 1743.0 3858.5 2354.7 2086.6 1288.4 4642.0 1177.2 2185.1 1984.7 1484.1 2312.8 1911.4 1179.0 1757.0 2109.6 1239.7 1454.4 3025.5 1392.6 1936.0 1152.7 1417.8 867.8 1087.6 2507.7 845.7 1238.7 1366.4 1688.3 1757.9 1356.3 5348.4 1684.4 3262.9 2632.2 2121.6 2131.1 3065.4 2048.1 2372.7 1501.1 2872.4 1787.4 2146.5 981.5 3290.2 1875.7 2799.7 2592.8 7841.1 1564.8 1589.2 1662.2 2231.7 1644.2 1719.8 1672.3 1765.4 1713.9 1670.6 1597.4 1980.8 1607.0 1003.2 1168.4 46.7 786.3 979.5 1548.2 1890.9 796.2 426.2 763.6 1161.1 370.3 948.0 1262.5 551.8 120.9 1661.1 1082.7 1377.9 1829.3 1114.8 3648.2 961.6 510.0 870.9 922.4 4506.0 29.1 880.2 996.8 1202.3 1270.6 799.9 1800.7 412.4 669.3 1509.8 1168.9 233.9 37.3 1351.2 1310.2 589.0 1180.7 2126.9 592.4 826.6 1812.5 50.6 1001.9 912.0 1051.5 30.7 133.6 751.3 1879.5 775.2 700.4 974.6 1970.0 3101.7 2080.6 506.8 880.9 714.4 3554.9 3297.7 1090.7 739.1 1112.3 1815.4 1231.6 935.0 993.8 1036.2 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 654.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.08e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 61.6 45.8 57.8 40.1 60.8 48.3 58.1 59.9 71.5 56.2 51.4 51.4 46.7 51.6 55.8 46.7 58.3 71.4 54.2 74.3 59.7 71.8 58.3 39.9 39.6 56.6 57.8 52.5 56.5 79.4 35.3 48.6 58.0 40.0 54.4 68.4 54.6 39.6 175.1 57.0 42.5 42.9 62.3 40.3 59.2 56.8 58.8 67.9 73.7 88.6 48.4 61.6 46.9 64.1 104.8 46.6 654.4 22.8 189.8 243.1 104.0 137.1 171.9 112.8 139.2 51.0 124.0 51.4 117.1 188.5 94.5 43.8 400.7 140.5 202.1 125.9 120.3 177.2 59.0 142.5 91.6 83.5 81.3 96.7 127.9 99.3 94.8 114.6 150.9 105.4 91.9 93.3 280.7 57.5 152.6 77.7 125.6 71.2 217.6 147.0 66.8 122.1 193.2 91.1 113.4 126.3 59.7 62.8 58.1 178.3 33.7 121.5 140.1 218.2 143.2 129.4 162.0 81.1 55.0 143.7 215.7 32.6 124.3 29.1 28.2 53.7 17.6 25.4 21.3 15.0 13.6 22.7 18.4 9.5 14.3 15.7 25.6 18.5 36.3 60.0 5.9 20.5 57.8 60.8 59.9 71.5 74.3 59.7 56.6 57.8 58.0 62.3 58.8 64.1 69.3 9.6 24.2 100.9 50.3 102.9 83.7 111.2 70.6 151.8 84.4 74.4 37.7 108.7 63.7 55.2 29.2 31.9 84.8 56.4 229.0 95.8 36.9 54.3 51.6 59.8 59.8 108.8 115.4 101.9 83.4 81.2 60.6 57.8 23.5 61.8 72.1 55.9 85.3 75.7 67.7 39.4 91.6 71.4 63.9 79.7 62.7 76.3 129.9 71.2 62.4 103.9 79.3 160.9 158.3 113.7 41.6 36.1 87.7 74.8 58.9 172.6 51.8 73.3 26.3 56.4 81.7 83.1 191.6 77.3 122.3 36.0 55.4 57.9 50.9 103.4 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 544.4" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol NA NA 5800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: AB_2684756" "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favorable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 41.5 46.0 63.7 37.1 64.8 54.4 33.9 65.0 72.0 35.5 54.4 45.5 39.6 35.0 41.0 49.1 38.5 34.0 51.5 65.4 65.3 40.1 40.9 33.9 48.8 67.8 64.7 33.9 30.3 43.2 31.2 42.7 66.8 39.1 45.6 28.1 33.9 36.8 63.5 36.2 40.7 48.6 62.3 37.6 37.5 28.5 66.7 51.9 36.4 53.1 52.5 46.8 32.3 65.5 121.9 68.9 98.3 77.4 105.1 93.1 56.6 100.0 113.6 125.8 118.7 79.0 57.0 114.2 49.0 133.5 94.7 101.4 132.1 108.6 124.3 114.4 142.9 132.1 63.3 94.8 70.0 190.9 91.0 82.7 93.1 91.2 65.7 90.6 143.4 69.4 544.4 59.3 137.9 89.6 100.0 137.6 72.8 134.8 71.6 80.5 147.6 31.2 118.8 96.2 88.0 65.4 79.9 99.1 95.6 89.4 61.7 104.0 103.8 88.6 113.5 75.5 103.6 57.3 99.7 103.7 120.0 87.5 86.0 84.4 87.8 105.7 84.9 102.2 79.7 77.3 79.9 91.6 109.2 73.6 69.0 82.9 73.2 81.2 89.0 106.3 106.1 141.1 63.7 64.8 65.0 72.0 65.4 65.3 67.8 64.7 66.8 62.3 66.7 65.5 102.6 109.0 83.9 26.1 110.7 125.5 171.6 318.5 51.2 54.5 76.9 72.8 64.9 101.5 180.3 71.7 16.7 312.1 159.0 215.1 197.6 288.2 79.9 133.1 104.6 125.9 126.0 173.0 25.6 385.0 406.5 102.6 60.1 124.9 129.3 79.3 109.6 159.8 298.5 69.0 24.3 153.1 193.3 126.9 159.7 61.1 87.3 140.9 126.3 19.7 257.9 98.4 200.8 22.6 30.4 432.1 222.1 103.8 98.4 186.7 213.5 257.2 173.9 45.5 105.2 81.0 205.4 202.8 121.2 87.6 129.7 372.1 130.1 133.7 154.0 208.4 UBL3 "DKFZP434K151, FLJ32018, HCG-1, PNSC1" ENSG00000122042 "Ubiquitin like 3" O95164 13 29764371-29850617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 350.5;Late spermatids: 316.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBF TERT88: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053772, HPA058781" Uncertain Approved Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Centrosome "HPA053772: AB_2682258, HPA058781: AB_2683818" "unprognostic (2.83e-2)" "unprognostic (5.48e-2)" "unprognostic (3.20e-1)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (2.20e-1)" "unprognostic (3.22e-1)" "unprognostic (3.22e-2)" "unprognostic (3.63e-1)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "prognostic favorable (4.23e-4)" "unprognostic (8.49e-2)" "unprognostic (1.96e-1)" "unprognostic (5.01e-2)" "unprognostic (2.84e-1)" 23.3 20.7 39.6 17.8 49.6 22.2 29.3 58.0 47.1 38.3 25.9 28.6 27.7 42.4 25.6 42.9 27.1 31.5 20.5 38.5 52.3 35.1 41.7 36.9 19.3 51.5 54.8 30.7 55.8 30.0 17.1 22.6 49.0 22.5 27.7 47.2 29.2 22.7 29.7 24.1 29.0 30.7 53.8 25.2 72.8 22.4 47.3 21.5 40.4 35.5 19.0 19.5 23.6 61.3 12.5 7.8 23.9 14.5 33.0 31.7 25.3 101.2 59.2 42.5 34.0 18.6 27.7 10.9 22.3 101.3 19.7 12.2 11.0 15.1 121.0 17.3 13.5 11.5 9.9 15.0 10.4 17.0 14.8 18.8 48.2 22.4 14.3 36.7 15.5 12.9 5.8 7.7 18.1 84.5 12.8 14.3 14.3 29.3 11.1 14.5 30.8 12.5 28.2 14.7 27.8 13.9 14.3 49.0 106.8 50.6 26.4 28.6 13.4 54.7 13.6 30.3 13.8 17.7 7.4 8.2 19.4 14.4 37.0 10.4 11.2 10.0 10.7 11.4 5.0 2.9 13.5 10.5 10.9 4.1 7.6 9.5 11.2 6.9 13.0 5.1 34.7 9.1 39.6 49.6 58.0 47.1 38.5 52.3 51.5 54.8 49.0 53.8 47.3 61.3 60.7 192.3 46.2 58.4 47.0 77.0 99.6 30.6 57.5 166.8 47.3 29.6 35.6 70.1 63.3 36.8 77.2 17.2 55.2 81.8 92.0 36.7 350.5 113.7 66.4 44.0 60.6 8.6 77.2 37.3 87.9 73.0 154.5 103.6 14.5 16.4 35.0 58.0 39.1 95.9 95.1 58.8 42.7 60.0 92.1 316.1 34.8 69.4 97.8 91.8 56.6 174.9 38.1 97.0 214.1 60.9 34.8 33.1 58.3 65.9 45.1 50.8 80.4 67.9 19.7 91.0 49.6 72.5 24.5 55.2 80.0 29.6 56.8 76.5 43.8 104.0 UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 167.4;Granulosa cells: 191.2;Hepatocytes: 65.7;Late spermatids: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" 10.2 17.3 17.0 7.1 12.0 8.8 14.1 12.2 16.1 10.4 0.0 12.5 13.1 10.4 49.9 10.7 13.2 13.5 4.9 13.3 5.4 22.1 44.1 8.7 8.1 10.3 4.2 79.9 33.0 20.5 2.8 15.6 10.6 16.3 16.3 11.6 8.5 18.6 3.7 16.9 12.1 10.8 1.7 11.1 12.4 37.1 9.2 14.3 25.9 5.4 9.7 10.4 3.3 12.7 16.4 17.0 11.7 12.2 17.9 25.2 14.3 29.5 17.2 15.2 19.6 27.6 6.1 26.8 23.2 24.5 25.9 14.8 3.1 16.8 24.6 23.9 27.2 77.0 14.0 33.0 27.3 18.1 41.8 20.2 17.4 25.6 12.7 13.6 14.1 12.8 71.9 21.8 35.5 16.1 18.6 14.6 22.9 52.2 12.9 21.4 10.9 18.3 27.7 22.4 6.4 17.7 8.3 26.0 52.1 14.1 16.8 30.4 17.3 17.0 7.8 8.2 28.3 8.8 29.2 19.7 15.0 29.0 25.5 0.0 4.6 0.6 6.2 4.9 5.4 4.7 3.3 5.8 5.2 1.9 3.0 5.5 0.8 2.8 2.4 6.5 3.2 2.7 17.0 12.0 12.2 16.1 13.3 5.4 10.3 4.2 10.6 1.7 9.2 12.7 20.5 3.2 8.2 5.5 5.2 0.0 5.4 0.0 8.0 2.5 7.5 7.6 4.3 17.2 3.1 14.7 20.9 23.8 10.7 7.5 7.9 9.7 167.4 9.1 18.6 12.4 8.5 12.8 5.4 5.3 20.2 22.8 9.7 11.3 14.0 191.2 21.4 65.7 22.0 11.8 7.8 9.7 0.0 16.7 0.0 180.4 14.3 8.9 0.0 6.5 11.6 8.1 12.3 4.5 16.3 3.1 6.0 9.8 6.7 4.9 6.9 25.4 0.7 2.2 6.6 8.7 10.4 16.1 24.2 13.0 0.0 15.2 6.6 27.1 11.8 4.4 UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Supported Nucleoplasm,Cytosol No No 700000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "CAB037139: AB_1841234, CAB037208: AB_1841235, HPA019678: AB_1858583" "unprognostic (4.16e-1)" "unprognostic (3.84e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (5.15e-2)" "unprognostic (6.46e-3)" "prognostic unfavorable (6.41e-4)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (9.71e-2)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (4.47e-2)" "unprognostic (3.97e-1)" "unprognostic (2.76e-2)" "unprognostic (8.84e-2)" "unprognostic (3.26e-2)" 20.7 56.9 20.6 20.2 24.2 33.5 34.2 20.3 25.2 15.3 17.2 35.4 21.6 12.4 63.2 58.0 13.0 17.7 29.3 21.7 20.5 32.2 50.9 15.0 21.3 18.6 18.9 7.4 30.9 23.9 22.9 24.6 18.5 19.5 39.5 9.7 27.2 18.2 53.9 48.6 19.9 25.1 18.9 15.9 25.1 43.3 20.5 25.7 44.4 40.6 34.6 44.3 26.6 21.0 196.0 31.9 26.9 18.8 49.9 58.6 78.6 72.3 70.3 90.7 100.5 177.5 92.1 100.4 50.2 75.7 70.2 105.8 64.1 175.3 137.1 53.8 55.9 62.2 50.7 114.9 71.6 150.4 45.7 52.6 118.7 71.7 114.2 38.4 90.1 79.6 70.0 27.9 138.9 70.2 62.4 100.2 40.3 229.0 95.1 49.5 42.9 66.3 108.4 77.9 81.0 23.8 40.8 78.3 34.5 58.2 45.7 42.0 70.8 39.6 47.9 42.7 98.2 39.5 45.5 117.1 80.4 161.3 29.0 57.6 68.7 49.3 29.9 134.4 39.6 51.5 54.1 43.0 99.5 51.5 53.0 49.5 15.6 62.7 117.9 134.9 71.8 50.1 20.6 24.2 20.3 25.2 21.7 20.5 18.6 18.9 18.5 18.9 20.5 21.0 18.2 9.6 23.4 9.1 20.3 76.3 80.4 197.5 35.9 9.3 48.8 66.2 27.2 28.6 88.2 46.0 2.1 105.2 32.9 39.0 92.0 146.2 198.2 35.4 17.4 26.6 24.0 24.4 22.5 143.1 163.6 25.1 23.9 36.2 24.1 19.3 13.9 45.7 88.0 16.8 22.3 54.6 81.4 28.8 28.8 43.5 16.8 32.8 26.6 18.7 33.3 17.3 22.6 22.6 24.9 153.1 44.3 11.7 33.3 133.1 40.4 119.6 48.0 8.9 19.7 24.5 73.5 159.3 36.8 64.8 79.1 169.0 22.1 47.6 60.8 96.2 UFSP2 "C4orf20, FLJ11200" ENSG00000109775 "UFM1 specific peptidase 2" Q9NUQ7 4 185399537-185425979 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 190.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039985, HPA043298" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA039985: AB_10794206, HPA043298: AB_10795037" "unprognostic (8.87e-2)" "unprognostic (1.85e-2)" "unprognostic (1.52e-1)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (3.63e-2)" "unprognostic (3.19e-2)" "unprognostic (3.69e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.07e-8)" "unprognostic (1.92e-1)" "unprognostic (8.12e-2)" "unprognostic (9.36e-3)" "unprognostic (6.70e-3)" 21.2 24.9 19.9 9.5 21.7 5.7 24.3 25.2 24.1 21.6 29.6 19.5 13.0 19.9 28.1 25.8 17.7 15.6 32.1 20.4 21.9 37.3 24.1 17.1 11.9 20.4 20.2 31.4 19.7 23.8 10.0 14.0 20.9 19.8 15.3 56.4 20.3 19.2 48.5 21.6 12.0 20.2 20.7 14.5 17.5 21.0 21.3 14.3 25.9 40.6 16.1 16.2 10.1 25.3 17.5 11.9 28.8 24.3 25.8 25.6 15.3 20.3 20.5 19.3 19.3 18.4 23.2 17.9 9.0 19.7 14.7 16.1 20.4 32.2 17.4 21.8 12.4 11.8 13.0 23.3 30.2 15.3 12.3 14.7 26.8 16.5 16.7 26.7 35.7 21.9 24.8 34.3 28.2 16.3 22.0 16.4 8.7 11.8 16.7 20.2 11.5 20.4 31.9 11.4 18.6 14.8 11.3 25.6 23.1 17.6 15.4 13.6 27.3 9.5 16.8 7.5 17.2 34.6 14.8 9.5 30.5 11.0 25.3 10.8 12.3 7.6 21.2 10.4 25.7 22.0 21.7 24.1 14.1 15.4 23.2 22.9 0.7 21.5 11.1 19.9 20.6 12.5 19.9 21.7 25.2 24.1 20.4 21.9 20.4 20.2 20.9 20.7 21.3 25.3 33.8 6.4 23.9 14.7 30.1 22.0 28.7 35.1 33.0 47.6 20.9 25.5 27.0 15.7 31.1 20.2 66.7 26.0 23.4 8.3 111.6 28.3 190.5 16.4 28.9 24.1 19.3 24.0 12.2 33.1 29.7 34.2 20.4 19.2 29.7 21.9 21.8 17.3 27.2 18.5 17.8 18.6 28.5 22.1 18.8 52.9 35.4 18.5 35.6 12.2 17.3 71.8 21.6 23.6 33.2 19.7 14.6 42.2 53.0 15.4 22.2 100.9 23.7 87.9 65.7 31.8 38.9 89.3 56.7 22.6 18.9 41.9 27.1 35.6 14.8 19.6 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 UPRT "DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3" ENSG00000094841 "Uracil phosphoribosyltransferase homolog" Q96BW1 X 75156388-75304885 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000805 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA000805: AB_1080482" "unprognostic (3.12e-3)" "unprognostic (5.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (1.18e-2)" "unprognostic (4.62e-2)" "unprognostic (1.04e-3)" "unprognostic (9.64e-2)" "unprognostic (1.37e-2)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.14e-4)" "unprognostic (6.09e-2)" "unprognostic (2.54e-2)" "unprognostic (2.74e-1)" "unprognostic (4.53e-3)" 6.2 10.9 7.2 6.3 7.4 13.4 7.9 7.4 8.7 8.1 8.1 7.6 10.9 5.9 8.9 7.9 7.2 6.1 9.3 7.1 8.2 11.4 8.6 7.6 8.9 7.2 8.3 6.1 6.5 14.0 7.0 5.8 7.9 9.2 7.9 6.4 8.7 6.0 8.9 5.6 8.1 6.5 7.4 7.3 10.3 1.9 8.1 8.9 10.2 10.8 8.2 6.9 4.7 8.1 11.6 7.6 8.9 8.1 9.4 9.9 8.4 8.0 9.2 8.4 9.6 7.2 7.7 16.3 6.6 8.5 15.1 4.8 20.7 6.8 13.9 14.3 8.0 10.2 7.8 9.1 9.0 20.2 20.1 7.5 5.0 11.2 6.1 13.4 15.1 13.1 12.1 15.7 22.6 4.8 22.7 12.4 17.8 8.6 13.0 10.7 22.8 8.1 21.9 6.4 0.6 9.2 11.0 11.4 11.4 15.7 5.3 12.6 12.6 10.6 6.3 19.4 6.8 10.7 36.5 15.8 11.2 21.9 6.9 6.9 7.3 9.2 7.7 10.6 9.0 8.2 7.6 8.0 10.9 7.0 9.4 8.3 1.4 14.4 17.9 5.2 13.5 7.1 7.2 7.4 7.4 8.7 7.1 8.2 7.2 8.3 7.9 7.4 8.1 8.1 8.5 6.4 5.0 8.1 8.0 6.2 8.7 10.0 3.4 8.5 5.3 3.8 6.6 5.7 11.2 9.2 0.0 8.4 8.1 5.3 27.4 8.8 2.0 4.8 4.1 8.6 6.0 4.6 8.8 6.0 15.1 5.2 5.1 4.1 24.1 5.2 11.7 6.0 11.6 10.1 8.8 5.3 22.4 16.1 8.8 1.8 4.4 10.8 14.2 3.7 7.8 9.4 13.4 13.0 8.4 5.6 3.2 3.4 9.8 5.5 8.4 15.4 6.1 7.2 6.6 4.8 7.1 0.7 2.4 4.2 6.0 12.2 12.1 6.5 7.2 7.4 UQCR10 "HSPC051, QCR9, UCCR7.2, UCRC" ENSG00000184076 "Ubiquinol-cytochrome c reductase, complex III subunit X" Q9UDW1 22 29767369-29770413 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4406.3;Distal tubular cells: 2296.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.09e-1)" "unprognostic (2.96e-3)" "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (2.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.75e-3)" "unprognostic (3.05e-2)" "unprognostic (9.24e-3)" "unprognostic (2.94e-1)" "unprognostic (1.12e-2)" "prognostic favorable (5.45e-5)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.80e-3)" 87.8 167.6 175.5 59.0 182.2 72.2 70.8 186.9 221.3 58.7 180.2 124.6 111.7 54.0 72.1 111.0 70.4 52.4 433.7 181.4 186.4 169.9 170.0 75.4 68.4 177.2 175.8 61.9 73.4 142.8 98.8 53.7 177.0 94.6 87.6 90.4 85.4 64.0 509.1 73.7 98.2 52.9 179.6 89.8 121.7 101.7 182.0 81.0 86.3 463.5 65.8 79.5 71.0 178.1 173.3 177.3 167.7 131.3 154.0 100.8 93.1 93.8 116.2 164.1 170.8 230.4 96.8 129.6 99.6 149.7 120.5 168.2 200.6 219.9 101.8 162.6 423.2 162.2 200.9 512.2 110.1 210.7 170.0 169.8 132.0 171.6 115.1 137.4 124.1 137.3 112.6 169.8 163.8 434.9 159.4 246.5 96.6 413.1 232.4 171.3 134.6 235.1 289.7 324.3 184.6 92.9 109.3 231.7 156.2 105.7 164.5 198.9 98.2 168.4 204.8 104.8 141.3 127.2 140.2 176.0 152.2 161.4 108.7 982.0 782.2 1009.7 455.0 820.3 503.6 1000.7 620.1 587.4 842.3 830.2 670.6 571.5 552.9 554.9 762.4 864.6 890.3 1160.1 175.5 182.2 186.9 221.3 181.4 186.4 177.2 175.8 177.0 179.6 182.0 178.1 138.4 246.8 290.2 42.7 231.0 181.8 205.4 1090.3 149.1 167.6 354.1 421.9 4406.3 443.2 563.5 627.1 77.2 680.2 215.8 819.5 2296.9 438.5 356.7 361.2 190.9 200.9 380.1 380.7 26.0 553.2 549.2 291.0 423.5 345.2 150.1 279.1 180.2 1306.4 737.2 114.4 33.8 791.0 783.3 390.7 254.0 652.3 234.6 337.1 311.3 15.9 424.2 455.0 310.0 16.1 32.4 499.6 771.6 206.5 293.4 335.2 1114.8 1872.1 522.9 307.1 210.4 150.2 327.7 577.2 165.7 490.0 281.7 582.0 226.2 346.5 782.7 389.6 UQCRC2 "QCR2, UQCR2" ENSG00000140740 "Ubiquinol-cytochrome c reductase core protein 2" P22695 16 21953288-21983660 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 722.2;tongue: 933.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 556.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007998, HPA019146" Enhanced Enhanced Mitochondria NA NA 180000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA007998: AB_1858648, HPA019146: AB_1858649" "unprognostic (1.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.49e-3)" "unprognostic (3.35e-1)" "unprognostic (1.26e-2)" "unprognostic (6.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (8.87e-2)" "unprognostic (1.67e-2)" "unprognostic (2.43e-2)" "prognostic favorable (6.58e-9)" "unprognostic (2.33e-1)" "unprognostic (9.78e-3)" "unprognostic (4.67e-3)" "unprognostic (7.36e-2)" 158.8 117.7 69.0 103.1 71.2 127.7 108.4 75.5 90.0 90.8 113.9 259.8 292.5 98.2 72.7 157.4 109.7 99.5 559.4 72.4 73.7 240.0 245.1 75.4 120.0 74.1 69.5 114.5 89.7 257.2 39.8 96.5 72.7 95.6 262.8 142.3 133.8 104.3 722.2 85.4 233.6 121.2 65.8 80.9 153.2 55.8 76.5 131.3 107.9 933.2 149.3 153.6 59.8 73.3 173.9 193.1 116.5 66.4 154.3 186.8 169.1 163.8 160.6 177.5 174.5 347.9 177.7 338.9 144.3 170.4 129.8 324.6 222.3 212.7 193.7 151.4 178.4 185.9 166.1 494.3 164.6 249.1 501.2 232.3 229.4 130.3 186.2 169.4 248.1 224.1 217.9 159.1 177.2 230.6 288.6 175.0 124.6 261.1 148.8 310.9 263.6 390.0 285.8 214.6 154.4 114.9 237.2 318.6 190.3 151.6 354.4 264.1 179.3 103.3 98.1 104.0 148.0 126.3 87.2 302.7 188.7 239.8 126.4 80.1 128.7 71.4 80.0 147.8 103.3 96.0 98.3 89.3 153.9 77.9 106.8 97.6 45.9 101.8 148.1 67.6 134.8 157.3 69.0 71.2 75.5 90.0 72.4 73.7 74.1 69.5 72.7 65.8 76.5 73.3 105.5 64.1 52.5 81.9 81.1 90.6 190.8 444.0 74.6 109.1 91.7 79.6 556.2 84.4 194.9 71.7 87.6 238.3 82.6 233.4 455.9 124.5 88.0 72.0 55.7 91.3 113.8 92.4 65.0 109.6 157.6 89.0 144.3 65.8 92.6 99.6 84.3 122.3 195.5 69.0 74.0 224.4 238.0 145.1 100.6 89.9 68.3 104.6 131.6 27.2 162.1 108.0 91.6 60.3 50.7 97.2 214.0 97.0 72.9 114.4 378.0 306.9 110.2 152.6 78.9 94.1 109.5 68.9 56.7 132.0 88.4 278.3 91.3 170.2 358.7 204.3 UROS ENSG00000188690 "Uroporphyrinogen III synthase" P10746 10 125784980-125823258 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044038 Approved Approved Nucleoplasm,Cytosol NA NA 69000 "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm Cytosol "HPA044038: AB_10966692" "unprognostic (8.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.77e-1)" "unprognostic (7.19e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (5.82e-2)" "unprognostic (1.27e-1)" "unprognostic (4.35e-3)" "unprognostic (4.23e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (3.93e-1)" 27.9 41.3 54.1 13.4 55.3 67.5 26.9 40.6 64.5 15.9 33.0 29.9 20.9 21.4 56.9 24.9 19.3 15.6 73.2 56.3 45.8 40.7 59.7 20.5 18.8 41.6 48.1 22.5 32.9 30.0 29.9 11.3 43.5 27.4 16.5 26.2 29.6 19.1 83.8 23.0 24.2 18.1 40.2 28.0 29.6 31.2 51.8 18.6 32.5 80.0 19.1 27.3 17.0 47.8 45.5 56.3 29.8 74.9 38.5 42.2 51.9 51.4 94.5 39.0 34.6 22.9 54.0 58.4 24.7 72.9 24.3 23.5 18.5 43.1 31.3 78.1 39.9 125.3 27.9 40.1 67.3 50.7 29.7 59.3 20.7 25.8 66.0 47.5 34.4 48.5 24.4 54.1 63.5 65.2 51.2 72.8 37.7 31.8 54.0 33.1 34.1 37.3 53.9 28.2 26.2 46.8 51.6 41.8 80.7 30.8 40.4 59.1 33.8 52.3 19.6 38.1 48.2 50.7 36.8 40.6 75.6 23.1 26.3 4.9 31.9 4.6 30.1 33.1 33.9 30.1 29.3 38.6 53.5 37.5 38.1 29.6 2.1 53.6 31.9 25.3 29.8 38.1 54.1 55.3 40.6 64.5 56.3 45.8 41.6 48.1 43.5 40.2 51.8 47.8 19.0 19.2 23.1 20.5 34.3 9.3 12.0 31.8 9.6 49.3 36.2 39.5 70.5 40.0 28.6 36.8 45.9 60.8 36.3 19.1 101.8 59.7 57.0 11.2 25.5 22.2 14.5 231.5 23.9 59.6 47.4 33.3 23.9 16.9 11.4 112.3 28.2 53.4 79.3 47.1 25.2 25.6 40.7 47.8 20.8 123.7 35.8 31.6 62.2 9.4 58.7 77.0 69.0 13.6 29.6 42.7 15.8 40.6 46.9 27.3 52.9 142.6 20.4 42.3 6.6 22.8 36.7 55.7 100.9 28.5 12.8 20.0 37.8 55.0 38.8 21.3 USP51 ENSG00000247746 "Ubiquitin specific peptidase 51" Q70EK9 X 55484616-55489202 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 51.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.7;Muller glia cells: 32.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SuSa: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001942 Uncertain Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Nucleoli fibrillar center" "HPA001942: AB_1080536" "unprognostic (1.19e-2)" "unprognostic (4.65e-2)" "unprognostic (3.67e-2)" "unprognostic (1.02e-3)" "unprognostic (8.08e-2)" "unprognostic (3.26e-1)" "unprognostic (3.17e-3)" "unprognostic (2.07e-3)" "unprognostic (5.69e-2)" "prognostic favorable (5.70e-4)" "unprognostic (1.01e-3)" "unprognostic (1.27e-1)" "prognostic favorable (2.63e-5)" "unprognostic (2.81e-3)" "unprognostic (5.92e-2)" "unprognostic (5.85e-2)" "unprognostic (1.63e-1)" 1.4 3.1 2.5 0.9 2.7 0.5 1.7 2.8 2.8 1.9 4.2 0.8 0.4 3.1 51.7 0.6 5.5 0.8 2.1 2.2 4.2 3.7 1.2 1.5 1.1 2.2 3.1 6.5 1.1 5.6 1.4 2.4 2.4 2.4 0.8 3.1 0.8 2.5 0.4 1.1 0.7 1.9 2.5 1.8 0.8 2.3 3.8 2.4 5.3 1.1 1.2 0.9 0.7 2.5 0.0 0.6 3.9 1.1 1.9 1.0 0.0 0.6 0.3 0.7 0.9 1.2 0.5 0.0 4.6 0.8 0.8 0.2 1.0 0.4 1.2 1.3 0.0 1.0 0.2 0.0 0.8 2.5 0.2 3.9 0.0 0.4 0.0 0.3 0.2 3.0 3.1 3.0 0.6 2.6 2.4 1.3 4.8 0.0 0.2 3.4 0.7 1.5 0.9 0.1 0.0 0.7 1.1 0.1 3.7 7.0 0.9 1.3 0.2 1.5 2.1 0.4 0.1 4.7 2.0 0.9 1.0 1.4 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 2.7 2.8 2.8 2.2 4.2 2.2 3.1 2.4 2.5 3.8 2.5 5.1 3.2 5.5 3.3 2.6 0.9 2.2 0.9 2.2 23.7 3.8 7.4 6.9 1.5 2.0 3.7 6.2 4.3 1.2 0.2 9.8 1.5 0.3 9.0 9.2 6.0 3.6 5.0 2.7 0.0 2.2 8.1 0.0 2.1 1.3 7.9 6.4 0.7 7.6 6.7 5.0 0.5 0.0 5.6 2.5 1.0 4.1 4.7 5.4 1.9 0.3 32.9 3.1 3.5 3.7 0.2 0.3 8.2 1.0 1.0 0.0 13.1 11.2 16.4 0.0 7.1 5.0 11.4 12.5 1.0 0.4 2.7 3.1 13.0 0.4 0.5 UTP14C "2700066J21Rik, KIAA0266" ENSG00000253797 "UTP14C small subunit processome component" Q5TAP6 13 52024691-52033600 "Predicted intracellular proteins" "Differentiation, Meiosis, Ribosome biogenesis, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;JURKAT: 2.2;MOLT-4: 1.3;NB-4: 5.7;RPTEC TERT1: 2.1;THP-1: 2.9" "HPA047217, HPA054023" Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA047217: AB_2679987, HPA054023: AB_2682346" "unprognostic (7.89e-2)" "unprognostic (5.98e-2)" "unprognostic (4.47e-1)" "unprognostic (1.25e-1)" "unprognostic (2.33e-3)" "unprognostic (2.51e-1)" "unprognostic (2.02e-1)" "unprognostic (3.30e-1)" "unprognostic (7.16e-2)" "prognostic unfavorable (7.52e-4)" "unprognostic (7.35e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.46e-5)" "unprognostic (2.44e-2)" "unprognostic (3.43e-1)" "unprognostic (1.74e-1)" "unprognostic (3.04e-2)" 5.7 5.2 3.8 0.0 3.5 0.0 5.2 3.6 4.4 5.9 4.0 6.1 0.3 7.1 0.0 4.4 5.9 0.0 6.2 3.4 3.5 5.9 7.7 4.7 0.6 3.3 3.9 5.5 6.8 1.2 5.5 0.0 3.3 5.3 0.0 2.2 6.6 0.0 6.7 3.7 5.6 0.2 3.3 5.1 5.9 3.2 3.7 1.8 6.1 2.4 0.0 5.5 5.1 3.8 0.0 0.0 1.2 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.2 1.3 5.7 0.0 0.0 0.0 0.5 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 4.4 3.4 3.5 3.3 3.9 3.3 3.3 3.7 3.8 9.9 6.4 17.5 8.5 8.2 5.9 5.6 10.8 9.6 13.9 13.7 7.9 23.8 12.8 15.8 16.5 4.2 10.1 5.1 21.2 0.0 7.3 0.4 9.1 13.9 13.9 18.6 19.9 8.9 7.6 9.6 13.9 5.1 12.4 11.4 14.4 14.6 33.6 9.3 25.2 9.0 14.7 8.2 13.5 3.9 0.8 10.5 8.1 8.8 5.6 8.2 14.1 10.3 6.6 10.7 7.7 11.3 14.3 8.4 12.7 9.9 6.4 14.8 11.6 6.6 20.2 12.6 7.2 13.3 14.0 8.4 7.0 7.2 9.4 14.1 6.7 VEGFC "VEGF-C, VRP" ENSG00000150630 "Vascular endothelial growth factor C" P49767 4 176683538-176792922 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 39.3;Endothelial cells: 22.0;Leydig cells: 13.7;Microglial cells: 36.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 146.5;HBF TERT88: 114.4;hTEC/SVTERT24-B: 116.5;LHCN-M2: 129.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 7.0" "Secreted to blood" NA NA 383000 340000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (4.18e-1)" "unprognostic (4.07e-2)" "unprognostic (4.84e-3)" "unprognostic (1.15e-2)" "unprognostic (2.83e-2)" "unprognostic (3.05e-3)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.88e-5)" "unprognostic (4.53e-1)" "unprognostic (2.80e-2)" "unprognostic (2.23e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (1.89e-3)" "unprognostic (4.41e-2)" "unprognostic (2.54e-1)" "unprognostic (1.22e-1)" 25.0 6.9 2.6 4.2 2.5 0.2 16.7 2.7 2.8 9.7 2.1 4.7 2.4 7.3 1.8 4.0 8.5 6.8 12.7 2.4 2.4 6.7 4.2 16.8 8.0 3.1 2.8 5.9 1.8 2.7 1.5 19.3 2.9 5.1 3.3 1.2 7.4 5.0 3.1 5.1 6.8 6.6 2.6 3.9 3.2 1.4 3.7 1.1 27.7 4.1 3.4 10.3 7.6 2.5 5.9 2.8 1.8 0.0 25.5 25.3 0.0 146.5 87.3 79.2 62.5 0.0 0.7 0.0 0.0 82.7 33.1 4.4 1.3 54.8 114.4 0.1 2.8 0.0 3.8 0.0 13.9 0.0 0.0 27.0 2.5 116.5 80.5 79.3 49.7 0.0 0.0 0.0 129.9 2.1 0.0 0.0 1.3 0.0 47.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 2.3 3.3 0.1 0.7 0.7 0.2 24.2 83.6 9.2 20.8 42.1 0.2 0.0 0.0 34.9 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.6 2.5 2.7 2.8 2.4 2.4 3.1 2.8 2.9 2.6 3.7 2.5 39.3 3.2 0.0 10.1 0.1 2.4 1.3 3.2 0.0 1.0 3.2 1.7 1.5 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.5 3.1 8.3 10.9 22.0 0.0 0.0 2.0 0.0 0.0 9.1 0.0 11.0 0.0 8.5 10.0 0.0 0.3 1.7 2.0 0.0 4.1 0.3 2.2 1.2 13.7 0.4 3.6 36.5 0.0 3.4 0.0 1.5 0.6 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.2 0.0 1.9 11.7 0.2 2.0 0.3 2.0 0.0 0.2 1.9 0.0 3.6 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6 VPS13D "FLJ10619, KIAA0453" ENSG00000048707 "Vacuolar protein sorting 13 homolog D" Q5THJ4 1 12230030-12512047 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.4;Inhibitory neurons: 149.2;Late spermatids: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027332, HPA051621" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" Cytosol "HPA027332: AB_2672223, HPA051621: AB_2681555" "unprognostic (2.97e-1)" "unprognostic (8.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.75e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-3)" "unprognostic (3.33e-1)" "unprognostic (2.00e-2)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "prognostic favorable (7.42e-12)" "unprognostic (5.13e-1)" "unprognostic (1.72e-1)" "unprognostic (4.04e-2)" "unprognostic (8.31e-2)" 10.9 6.9 14.3 4.4 17.2 5.0 10.3 14.5 17.9 13.7 18.1 12.2 3.8 8.1 8.7 12.6 8.9 5.3 21.9 15.8 14.5 10.5 10.4 8.8 6.4 14.6 16.5 8.9 10.9 13.4 7.7 5.3 14.3 17.4 6.4 14.1 10.8 9.3 18.1 24.7 8.7 6.0 13.4 9.3 11.1 6.1 17.8 6.6 15.5 15.3 6.2 9.6 10.6 16.6 9.3 5.2 5.8 4.4 15.1 11.9 2.7 4.4 7.7 7.4 7.0 3.5 6.4 8.7 5.4 12.6 6.2 8.3 10.1 8.7 10.3 4.7 3.4 7.4 8.1 2.8 6.3 10.8 3.7 10.1 11.9 9.5 9.3 9.2 12.0 8.2 15.5 4.3 6.9 4.3 6.4 4.2 2.3 5.0 6.5 5.5 6.9 2.6 5.3 5.4 2.8 3.8 12.9 9.4 9.0 5.4 8.1 3.6 13.1 4.6 4.7 12.0 3.7 3.8 3.3 13.4 5.2 7.5 7.1 3.2 0.7 0.5 1.1 0.7 1.2 0.9 1.2 0.8 0.6 1.6 1.1 0.9 0.9 0.7 0.5 1.5 0.6 0.3 14.3 17.2 14.5 17.9 15.8 14.5 14.6 16.5 14.3 13.4 17.8 16.6 28.9 19.2 23.4 111.0 19.8 21.7 45.1 23.2 19.9 38.1 18.8 12.8 68.0 14.3 35.7 18.4 73.0 8.4 20.3 24.7 3.9 9.1 83.1 20.6 23.5 23.0 14.4 9.4 181.4 14.4 7.2 19.4 28.1 48.1 12.6 26.3 17.9 21.2 11.5 47.1 149.2 15.1 18.3 17.3 15.5 208.7 23.0 17.5 12.4 79.6 16.7 23.0 17.5 78.4 107.4 17.0 11.2 21.8 11.8 32.0 18.2 9.8 32.0 34.1 46.0 23.4 46.5 18.8 12.3 38.2 31.4 14.8 21.4 20.3 15.5 37.3 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 WDR61 REC14 ENSG00000140395 "WD repeat domain 61" Q9GZS3 15 78277835-78299703 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039932, HPA040065" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 28000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "HPA039932: AB_10796336, HPA040065: AB_10793926" "unprognostic (1.08e-1)" "unprognostic (1.85e-2)" "unprognostic (8.91e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.36e-1)" "unprognostic (2.44e-1)" "unprognostic (1.60e-1)" "unprognostic (3.05e-1)" "unprognostic (2.74e-3)" "unprognostic (4.21e-1)" "unprognostic (5.72e-2)" "prognostic favorable (2.03e-10)" "unprognostic (1.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.18e-1)" "unprognostic (1.09e-2)" 38.8 52.7 34.5 29.6 36.5 61.5 59.9 50.4 63.0 40.8 31.1 39.5 36.2 34.9 115.7 40.1 46.6 28.6 41.0 40.8 40.4 60.8 50.9 34.6 37.4 41.5 41.2 34.6 41.3 55.6 49.9 35.5 40.0 46.0 43.5 49.4 39.5 37.4 45.4 52.1 30.4 41.4 38.2 29.9 33.5 49.0 37.0 48.5 56.8 38.2 46.0 41.4 32.4 61.5 39.3 92.4 74.3 77.4 74.1 61.6 56.1 60.9 68.6 76.6 73.6 87.9 67.9 80.7 72.6 69.8 119.2 78.2 165.8 71.5 58.3 53.9 123.8 66.2 79.9 84.6 62.6 99.2 63.3 52.8 50.5 30.8 24.0 52.7 82.7 80.0 113.1 78.8 92.5 116.6 82.3 81.6 54.3 98.5 76.2 74.7 59.7 89.1 81.3 112.3 103.7 56.2 88.0 90.9 323.7 76.9 56.0 124.2 58.2 53.7 66.0 38.2 103.6 69.3 113.7 113.0 80.5 153.3 112.6 39.0 91.2 33.6 59.6 100.0 65.0 66.4 59.7 62.1 134.2 53.5 62.2 68.6 7.7 72.4 86.0 71.6 72.7 89.1 34.5 36.5 50.4 63.0 40.8 40.4 41.5 41.2 40.0 38.2 37.0 61.5 38.7 35.3 44.7 20.5 26.7 49.1 61.5 105.0 31.9 57.2 44.8 47.2 25.8 28.6 57.5 38.6 47.9 106.1 29.2 23.2 125.2 62.5 32.2 41.5 38.6 42.2 23.4 37.6 34.6 55.6 78.1 51.0 20.4 29.1 47.5 49.1 40.0 47.0 66.1 43.7 36.8 38.0 93.6 37.0 47.2 12.4 50.1 37.0 58.7 12.2 61.1 81.9 42.2 17.1 33.1 41.0 28.5 50.8 36.4 51.6 35.4 132.7 70.1 50.7 6.6 37.8 90.2 122.4 60.2 38.3 58.7 92.4 31.7 59.4 52.4 57.7 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WDSUB1 "FLJ36175, UBOX6, WDSAM1" ENSG00000196151 "WD repeat, sterile alpha motif and U-box domain containing 1" Q8N9V3 2 159235798-159286703 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036840, HPA058172" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "Nucleoplasm, Cytosol" "HPA036840: AB_10670926, HPA058172: AB_2683628" "unprognostic (1.37e-2)" "prognostic favorable (3.35e-4)" "unprognostic (2.56e-1)" "unprognostic (7.33e-3)" "unprognostic (3.44e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.76e-3)" "unprognostic (4.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (6.75e-2)" "unprognostic (3.46e-3)" "unprognostic (8.49e-2)" "unprognostic (1.72e-1)" "unprognostic (1.00e-2)" "unprognostic (2.87e-2)" 6.7 10.9 9.1 4.6 10.2 10.6 12.0 10.7 12.0 7.8 11.7 6.7 4.9 8.2 17.5 7.5 9.8 5.9 10.1 8.9 9.3 23.5 6.9 9.0 7.9 9.7 9.3 13.5 10.6 13.9 9.1 9.7 9.8 9.1 7.6 11.1 10.4 6.8 6.7 6.9 5.8 6.6 8.9 8.6 7.4 6.7 9.4 7.0 17.3 6.5 5.8 6.2 6.3 11.7 8.4 6.3 5.4 9.0 10.1 11.4 19.1 6.7 13.0 11.4 20.4 13.7 13.6 11.7 6.9 9.9 20.3 5.2 15.9 5.9 16.1 4.5 13.4 12.1 6.8 14.0 12.2 10.2 15.6 6.7 21.5 14.4 12.0 22.2 9.8 14.9 16.0 8.5 11.1 8.8 7.3 18.5 7.5 14.3 13.6 11.3 8.3 6.2 13.6 12.2 10.3 6.8 7.0 8.6 15.9 26.0 6.7 17.3 4.1 8.2 6.2 11.8 6.5 4.2 7.7 10.7 14.4 12.6 5.3 3.9 11.1 3.5 14.3 8.6 10.9 11.8 5.6 9.1 12.2 9.9 6.7 8.0 0.8 20.8 7.9 11.6 3.3 7.8 9.1 10.2 10.7 12.0 8.9 9.3 9.7 9.3 9.8 8.9 9.4 11.7 8.2 12.8 6.8 28.4 10.7 5.4 8.7 13.0 11.4 6.9 9.3 8.0 11.3 10.0 11.3 20.2 2.1 25.4 11.2 5.1 35.2 9.5 4.5 13.7 6.9 7.0 5.4 6.7 42.4 3.6 9.2 9.9 10.2 16.1 12.0 13.2 6.4 2.0 17.3 5.0 52.0 4.5 12.2 14.8 4.8 2.9 12.8 10.2 5.4 29.0 9.2 6.6 14.4 31.7 34.6 4.0 7.0 11.3 3.8 6.8 6.9 23.7 15.0 9.7 0.0 12.0 7.8 10.1 22.5 11.1 6.3 23.0 9.1 12.7 7.1 7.3 WWC1 "KIAA0869, KIBRA, PPP1R168" ENSG00000113645 "WW and C2 domain containing 1" Q8IX03 5 168291645-168472303 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 142.3" "Cell type enhanced" "Detected in many" "Astrocytes: 162.2;Cone photoreceptor cells: 91.8;Endometrial ciliated cells: 81.8;Glandular and luminal cells: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 120.2;RPTEC TERT1: 260.4;SK-BR-3: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038016, HPA038017" Approved Approved "Golgi apparatus" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA038016: AB_10697091, HPA038017: AB_10669513" "unprognostic (3.60e-1)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "unprognostic (1.51e-1)" "unprognostic (6.77e-3)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.31e-2)" "unprognostic (7.38e-2)" "prognostic favorable (1.95e-8)" "unprognostic (2.81e-3)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" 7.8 0.6 41.8 2.9 43.3 0.1 21.2 41.0 39.7 6.0 50.4 6.4 24.3 2.8 6.8 22.9 17.2 8.7 1.6 40.3 41.3 73.3 38.1 20.2 3.0 56.8 47.0 0.8 28.3 23.5 7.8 10.2 43.6 16.4 6.1 17.8 142.3 11.8 0.0 19.9 20.2 1.1 46.6 0.7 22.9 1.7 54.3 1.3 29.7 0.0 6.9 9.3 10.1 38.6 50.6 56.4 9.2 0.4 0.0 0.0 96.8 3.7 0.9 17.1 15.3 120.2 73.6 0.0 58.6 1.2 47.4 35.0 18.9 46.1 20.1 0.1 18.6 0.0 28.6 29.9 0.9 4.4 0.0 6.0 13.9 32.3 28.5 13.2 0.0 3.0 0.0 7.2 1.3 56.4 0.0 0.1 13.3 60.8 8.2 0.0 0.4 29.1 260.4 68.8 30.7 11.4 66.5 136.4 17.1 11.6 67.8 4.3 0.0 3.0 34.2 0.4 36.9 0.8 0.4 0.2 3.4 0.1 8.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.8 43.3 41.0 39.7 40.3 41.3 56.8 47.0 43.6 46.6 54.3 38.6 0.3 64.1 72.3 162.2 1.3 11.9 14.7 6.0 1.8 1.4 35.7 25.7 1.8 34.3 42.1 58.8 91.8 11.6 0.6 17.9 13.7 44.9 0.4 81.8 10.8 1.3 7.8 0.0 50.1 40.5 2.3 5.3 15.3 149.2 1.3 5.6 1.1 16.9 1.3 0.0 27.9 7.8 6.1 0.6 1.1 0.1 1.2 4.2 10.6 8.4 1.1 18.1 0.0 17.6 1.9 73.1 10.9 0.7 0.1 38.8 18.9 61.8 36.7 9.1 0.0 0.2 5.6 0.3 5.0 7.3 13.9 18.2 2.1 2.5 12.2 16.5 WWOX "FOR, SDR41C1, WOX1" ENSG00000186153 "WW domain containing oxidoreductase" Q9NZC7 16 78099430-79212667 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" Oxidoreductase "Disease variant, Epilepsy, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 14 "Astrocytes: 927.8;Excitatory neurons: 270.5;Inhibitory neurons: 540.9;Microglial cells: 471.2;Oligodendrocyte precursor cells: 914.9;Oligodendrocytes: 793.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 85.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050992 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Cytosol "HPA050992: AB_2681299" "prognostic unfavorable (9.07e-5)" "unprognostic (1.14e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-2)" "unprognostic (2.32e-1)" "unprognostic (1.81e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-1)" "unprognostic (3.61e-3)" "unprognostic (4.33e-2)" "unprognostic (3.50e-2)" "prognostic favorable (4.49e-5)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.77e-1)" 8.6 6.3 18.6 4.0 23.9 4.2 7.4 24.0 20.3 8.6 21.2 5.2 5.3 8.2 10.1 7.7 9.0 7.4 5.2 18.8 22.5 12.7 12.0 5.3 4.6 24.0 22.4 7.6 8.3 12.1 9.8 5.3 25.3 7.7 3.2 6.9 8.5 6.4 3.3 7.1 4.5 5.1 22.0 4.7 6.0 9.3 21.0 9.0 21.8 2.1 6.0 6.7 7.1 30.0 11.1 9.5 9.2 7.7 11.0 5.3 11.1 1.6 3.2 3.7 3.2 7.0 9.6 19.5 8.6 1.5 5.2 10.0 5.1 1.3 2.6 11.0 26.8 6.0 1.9 15.7 7.5 16.7 3.4 5.9 3.8 2.3 2.4 0.9 4.4 25.9 9.2 4.2 2.6 85.7 27.7 21.9 8.6 5.9 5.7 32.2 3.9 19.1 5.3 3.9 17.6 10.0 7.1 11.9 4.0 9.3 12.8 12.0 1.6 2.7 10.4 2.2 6.4 0.0 18.3 41.2 10.4 8.4 4.6 7.0 9.1 2.1 11.4 7.9 13.4 9.3 8.2 9.1 7.7 6.6 8.4 8.3 0.7 9.1 5.8 14.5 13.5 6.0 18.6 23.9 24.0 20.3 18.8 22.5 24.0 22.4 25.3 22.0 21.0 30.0 12.0 6.4 6.9 927.8 9.0 9.2 21.2 8.0 19.4 7.4 12.1 16.1 8.8 17.2 13.3 14.7 4.2 25.7 10.9 4.5 33.2 12.4 43.1 18.2 13.9 9.5 9.6 13.3 270.5 10.3 11.9 12.0 9.2 7.6 12.7 18.7 13.2 18.9 9.2 5.0 540.9 5.1 0.0 5.6 5.7 38.2 14.0 7.7 5.4 471.2 5.9 46.3 9.2 914.9 793.5 4.5 5.9 17.7 18.4 11.5 8.7 28.3 18.7 12.2 6.6 10.3 11.8 19.7 17.9 13.3 6.8 17.4 9.9 12.1 6.8 13.0 YAF2 ENSG00000015153 "YY1 associated factor 2" Q8IY57 12 42157104-42238349 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 8 "Cardiomyocytes: 1187.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026867 Supported Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA026867: AB_1858911" "unprognostic (1.41e-1)" "unprognostic (2.24e-1)" "unprognostic (9.30e-2)" "unprognostic (3.06e-1)" "unprognostic (2.06e-2)" "unprognostic (4.12e-1)" "unprognostic (7.10e-3)" "unprognostic (2.70e-1)" "unprognostic (2.86e-3)" "unprognostic (2.44e-2)" "unprognostic (3.58e-2)" "unprognostic (5.57e-2)" "unprognostic (4.57e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-1)" "unprognostic (5.76e-2)" "unprognostic (1.20e-2)" 11.5 9.5 9.7 8.1 10.5 10.8 10.0 13.9 12.0 10.3 4.3 8.1 5.9 9.4 8.7 6.9 8.8 8.6 36.6 11.6 10.4 9.5 18.0 8.1 12.5 9.2 9.1 9.0 6.3 7.8 8.6 9.0 10.3 8.2 7.3 14.2 6.6 8.4 29.4 6.3 7.9 10.3 9.9 10.6 6.9 7.3 10.1 13.5 11.1 21.1 10.0 10.0 8.9 12.6 13.5 10.6 15.3 12.1 19.1 16.9 9.9 19.1 17.1 15.5 15.1 14.4 10.7 8.6 14.0 16.6 6.2 11.5 15.0 10.7 21.7 20.5 14.9 18.0 4.6 6.8 11.0 17.6 11.1 12.1 14.9 12.8 25.3 15.7 16.3 8.3 17.2 20.1 20.1 5.6 20.4 21.2 3.9 16.0 14.1 15.0 16.6 13.9 20.1 10.1 11.6 14.6 16.0 18.3 14.8 6.9 12.4 13.0 14.4 13.6 12.1 16.7 9.5 16.6 26.4 31.7 15.0 82.3 6.8 43.2 15.6 28.9 18.2 18.9 18.6 20.6 17.6 20.9 12.5 24.2 13.4 14.5 56.6 27.1 17.2 19.3 26.5 9.7 9.7 10.5 13.9 12.0 11.6 10.4 9.2 9.1 10.3 9.9 10.1 12.6 41.9 22.4 13.4 68.2 41.1 58.1 40.8 31.0 33.0 75.0 45.2 35.1 1187.5 31.5 27.6 20.2 85.5 40.1 71.2 22.7 62.6 32.2 33.6 27.7 43.1 61.7 38.9 36.2 105.5 45.5 22.4 49.7 18.3 37.0 70.5 88.4 50.7 104.7 27.8 144.7 89.4 33.1 46.8 44.7 61.3 15.9 58.1 37.6 42.7 83.4 48.8 94.6 84.5 97.0 57.8 35.3 26.8 76.8 44.6 37.2 29.9 66.0 20.1 99.7 105.2 44.8 63.8 38.0 38.2 30.5 51.1 45.3 58.7 36.2 27.5 32.7 YIPF2 "FinGER2, MGC3262" ENSG00000130733 "Yip1 domain family member 2" Q9BWQ6 19 10922185-10928681 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 159.1;Syncytiotrophoblasts: 174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019902 Approved Approved "Golgi apparatus,Mitochondria" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Mitochondria" "HPA019902: AB_1858925" "unprognostic (1.27e-1)" "unprognostic (8.56e-2)" "unprognostic (2.90e-3)" "unprognostic (8.38e-2)" "unprognostic (3.66e-1)" "unprognostic (3.96e-1)" "unprognostic (1.93e-1)" "unprognostic (7.65e-2)" "unprognostic (4.30e-2)" "unprognostic (5.62e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (3.28e-2)" "unprognostic (3.92e-2)" "unprognostic (5.99e-2)" "unprognostic (2.00e-2)" 29.5 43.5 18.1 15.9 18.7 29.6 34.1 20.5 26.6 41.7 30.7 34.7 31.8 38.1 26.8 51.0 35.2 30.3 31.6 19.4 20.3 45.1 56.1 32.8 16.8 22.4 19.6 39.6 114.3 33.4 108.2 38.9 21.0 40.3 15.8 6.5 105.7 23.6 24.8 33.8 29.9 14.2 18.2 27.7 39.2 76.8 19.4 14.3 47.5 10.3 11.2 32.6 39.6 20.4 64.9 22.3 17.5 25.4 40.0 38.9 30.1 48.9 71.6 36.6 52.9 68.1 51.6 12.8 80.2 56.2 16.7 49.8 11.9 47.6 9.5 41.7 43.2 24.2 27.3 39.1 62.1 42.5 49.3 35.7 33.6 24.7 35.4 47.7 26.2 31.1 31.6 69.2 22.9 109.4 27.4 42.7 29.4 44.3 55.2 22.8 14.1 65.3 33.0 30.2 45.4 22.2 35.2 56.4 48.8 15.3 51.7 60.1 39.1 41.6 15.3 60.2 36.7 96.7 42.5 24.2 65.1 72.9 43.9 39.2 18.8 9.3 13.3 21.3 10.4 16.3 10.4 12.3 22.3 9.5 9.3 13.3 3.1 12.1 19.4 34.1 12.6 10.4 18.1 18.7 20.5 26.6 19.4 20.3 22.4 19.6 21.0 18.2 19.4 20.4 20.5 16.0 21.2 2.6 16.0 6.8 41.6 22.4 17.1 19.4 46.9 37.8 0.5 27.1 27.3 35.0 16.7 109.5 20.6 31.9 27.4 69.3 131.1 23.0 20.1 19.2 43.3 17.2 6.4 80.7 114.1 36.0 33.6 29.3 21.6 22.5 22.5 23.0 38.7 18.5 6.7 69.4 14.2 15.3 5.2 34.6 35.1 20.5 5.4 5.6 21.1 23.8 16.5 3.5 3.3 50.3 47.7 25.6 55.4 51.6 52.5 27.0 26.1 16.4 6.6 20.0 21.9 159.1 16.6 22.6 7.0 174.3 13.9 27.9 50.6 50.0 YIPF3 "C6orf109, dJ337H4.3, DKFZp566C243, FinGER3, KLIP1" ENSG00000137207 "Yip1 domain family member 3" Q9GZM5 6 43511832-43516985 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 494.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014859, HPA063699" Supported Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Nucleoplasm "HPA014859: AB_1845729, HPA063699: AB_2685095" "unprognostic (2.82e-2)" "unprognostic (1.29e-1)" "unprognostic (2.29e-2)" "unprognostic (4.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.05e-1)" "unprognostic (2.15e-3)" "unprognostic (3.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.70e-3)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-2)" "unprognostic (3.55e-1)" "unprognostic (1.21e-1)" "unprognostic (1.10e-1)" 72.3 120.2 78.9 43.3 79.9 46.4 70.0 79.5 92.0 74.0 102.6 74.3 65.2 72.1 100.5 80.3 69.7 63.3 87.6 80.2 78.9 78.2 105.4 68.9 42.6 80.5 79.2 75.6 152.0 110.0 91.9 77.8 81.2 76.3 62.1 49.8 118.6 61.1 82.8 70.0 66.1 57.5 78.3 67.2 106.1 48.0 81.6 46.0 74.3 83.4 46.5 69.1 67.3 80.8 95.0 66.2 95.3 185.4 208.3 168.5 56.1 111.9 174.6 91.8 115.7 79.1 67.6 37.8 84.4 208.6 78.4 93.4 71.0 110.2 59.4 69.9 95.7 61.2 91.8 153.2 163.2 64.7 85.9 169.0 141.2 77.9 78.3 154.4 141.1 61.1 67.8 88.2 111.5 146.9 47.5 82.3 49.7 494.4 71.1 42.6 43.0 103.2 164.3 101.4 76.7 109.0 50.3 66.9 122.2 72.8 111.4 133.5 133.5 103.1 53.4 57.0 78.8 102.5 88.8 74.3 73.2 53.5 71.5 147.2 84.8 128.7 60.0 82.2 52.3 46.1 53.7 54.1 78.7 48.5 42.7 48.5 316.0 65.5 83.2 70.3 79.8 78.2 78.9 79.9 79.5 92.0 80.2 78.9 80.5 79.2 81.2 78.3 81.6 80.8 77.8 35.3 33.6 12.7 41.4 40.7 63.8 121.7 63.2 54.6 62.8 49.4 31.7 82.9 86.5 55.2 37.5 192.2 41.1 109.7 49.0 149.6 38.1 63.5 60.5 78.9 107.1 42.1 12.1 101.8 209.5 78.2 59.7 67.9 40.6 77.9 74.6 71.0 99.3 58.9 14.7 117.6 101.7 49.1 31.2 79.0 69.9 49.6 65.8 14.0 72.4 115.0 42.2 15.1 17.7 117.5 108.8 67.0 111.6 71.4 129.1 74.9 51.2 63.5 32.9 45.5 64.4 44.0 40.8 52.8 35.5 264.1 34.9 101.9 80.0 81.6 YIPF6 "FinGER6, MGC21416" ENSG00000181704 "Yip1 domain family member 6" Q96EC8 X 68498562-68537282 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003720 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA003720: AB_1080626" "unprognostic (5.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.72e-1)" "unprognostic (7.17e-2)" "unprognostic (5.90e-3)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (1.33e-2)" "unprognostic (3.15e-1)" "unprognostic (8.85e-3)" "unprognostic (8.48e-2)" "unprognostic (2.90e-2)" "unprognostic (3.25e-1)" "unprognostic (6.32e-2)" 14.3 14.7 13.9 7.8 15.7 6.6 14.9 15.6 15.4 14.5 15.4 12.5 11.7 13.3 14.5 11.6 13.2 11.1 11.6 12.9 16.0 18.9 21.6 12.4 6.4 15.9 16.5 10.5 14.5 20.6 15.0 18.2 14.9 19.9 14.1 14.3 16.4 14.5 16.9 10.7 11.4 12.9 15.1 8.3 15.3 6.2 15.7 6.7 21.8 16.4 7.4 12.4 8.4 15.5 23.5 22.4 22.6 7.9 28.7 17.8 24.8 18.0 22.5 13.8 17.4 23.5 23.5 0.1 32.6 15.1 22.8 18.2 29.8 12.2 23.2 6.8 20.2 10.4 22.6 19.6 26.4 11.4 14.3 17.6 22.3 20.5 25.4 24.1 13.8 13.4 16.6 22.3 18.8 24.8 6.6 9.7 24.0 34.0 23.3 6.7 27.5 12.3 22.9 25.9 23.5 24.6 30.6 20.9 21.7 20.4 12.9 11.8 18.8 15.4 14.8 49.2 35.0 12.2 15.0 4.6 22.8 17.2 26.1 5.3 4.0 4.7 2.2 4.7 1.5 3.9 2.2 2.0 3.0 2.1 2.2 1.9 10.5 2.9 4.2 3.6 2.6 2.8 13.9 15.7 15.6 15.4 12.9 16.0 15.9 16.5 14.9 15.1 15.7 15.5 42.1 70.5 99.6 25.5 25.6 34.9 62.3 110.0 21.6 54.6 47.4 32.3 33.7 32.9 88.6 57.0 47.9 101.6 19.8 43.8 35.2 47.4 25.9 50.9 35.2 41.7 54.4 80.4 18.8 43.9 111.3 53.1 27.5 47.8 53.7 33.6 42.1 60.2 44.1 45.4 21.9 61.8 93.6 25.9 42.0 63.2 42.6 38.5 35.6 23.4 23.4 63.5 29.9 26.7 34.9 47.3 34.7 47.4 42.7 90.4 42.4 62.4 81.6 52.7 26.3 50.8 44.6 31.5 28.1 31.4 43.3 278.8 29.0 29.6 33.5 89.5 YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350" Approved Supported Cytosol NA NA 83000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016200: AB_626619, CAB021109: AB_10060396, CAB047350: , HPA008445: AB_1844336" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-2)" "prognostic favorable (6.48e-6)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (2.73e-2)" "unprognostic (4.77e-3)" "unprognostic (4.53e-2)" "unprognostic (5.14e-2)" "unprognostic (1.59e-1)" "unprognostic (2.73e-1)" "unprognostic (1.92e-3)" "unprognostic (8.33e-2)" "unprognostic (2.57e-1)" "unprognostic (3.24e-2)" "unprognostic (8.94e-2)" 221.9 198.9 251.8 122.8 264.2 121.3 198.7 266.3 272.8 168.8 195.7 161.1 136.8 155.6 192.7 239.1 188.1 103.7 242.3 260.7 275.4 229.3 211.7 176.9 113.7 271.1 246.8 170.8 154.9 236.9 178.8 198.2 267.1 150.0 168.1 220.8 184.8 121.6 656.7 193.3 129.3 137.3 279.2 101.5 136.9 165.4 262.2 211.0 208.5 441.8 164.5 186.9 179.7 302.7 615.3 565.8 700.2 563.4 376.9 454.7 589.8 382.1 481.5 724.5 571.3 907.5 305.5 524.7 411.9 621.9 439.7 463.1 859.2 745.6 798.7 294.2 930.9 334.1 366.2 409.4 483.4 277.1 311.1 421.6 458.6 619.3 897.0 520.6 729.2 458.5 402.8 337.9 719.7 368.5 445.8 264.1 566.6 596.9 332.7 477.3 255.9 380.4 547.7 365.7 354.2 497.2 531.1 240.3 364.3 439.9 442.3 290.9 467.4 411.9 293.8 453.7 731.4 190.5 329.9 346.6 478.4 387.5 585.4 78.6 137.2 41.2 47.3 153.6 57.8 78.1 67.3 55.1 180.3 59.1 55.7 51.2 49.9 64.1 144.8 133.8 99.7 151.0 251.8 264.2 266.3 272.8 260.7 275.4 271.1 246.8 267.1 279.2 262.2 302.7 363.6 298.1 194.4 83.2 161.1 573.9 457.5 468.4 281.7 153.6 313.6 219.1 473.4 265.9 310.9 371.5 50.1 463.2 128.7 300.7 745.4 460.8 258.0 573.6 414.3 352.6 352.6 244.7 73.4 421.4 709.5 319.4 194.7 502.7 211.5 328.1 262.3 309.0 384.9 111.0 72.4 346.3 376.4 260.9 434.9 434.3 280.8 227.5 425.2 60.0 320.5 357.8 55.6 56.8 112.1 464.8 289.8 294.9 279.5 487.9 272.1 707.8 504.6 173.3 243.3 361.2 524.6 508.7 573.3 333.8 586.6 519.5 130.7 287.2 361.1 474.4 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 ZBTB16 "PLZF, ZNF145" ENSG00000109906 "Zinc finger and BTB domain containing 16" Q05516 11 114059711-114256765 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 105.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 134.8;Inhibitory neurons: 125.9;NK-cells: 119.4;Skeletal myocytes: 163.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 23.3;MAIT T-cell: 39.4;naive B-cell: 11.0;NK-cell: 10.9" "Group enriched" "Detected in many" 5 "B-cells: 11.0;NK-cells: 10.9;T-cells: 39.4" "Cell line enhanced" "Detected in some" "ASC diff: 71.5;ASC TERT1: 38.6;HEL: 40.7;HHSteC: 26.6;HSkMC: 26.7;hTCEpi: 30.6;hTERT-HME1: 25.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001499, CAB004540" Uncertain NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB004540: AB_2218941, HPA001499: AB_1079640" "unprognostic (2.21e-1)" "unprognostic (2.17e-1)" "unprognostic (7.30e-2)" "unprognostic (1.18e-1)" "unprognostic (2.53e-1)" "unprognostic (3.05e-1)" "unprognostic (1.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (8.79e-4)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.21e-4)" "unprognostic (2.57e-3)" "unprognostic (2.67e-1)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" 55.8 20.8 5.1 3.4 14.9 7.6 32.3 11.7 24.8 25.9 17.7 20.9 0.9 29.6 4.0 28.1 30.9 13.1 28.1 9.9 8.4 10.6 14.5 27.1 8.8 20.1 8.4 51.4 61.7 34.3 6.4 9.6 15.2 15.1 3.3 2.2 13.3 7.0 88.6 28.5 16.3 15.8 4.9 13.2 18.3 4.0 7.1 6.5 29.3 105.8 2.0 29.4 19.7 18.0 0.0 0.0 13.0 0.0 71.5 38.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 40.7 0.0 0.0 26.6 0.9 0.7 26.7 30.6 0.0 25.6 0.0 4.6 5.5 0.1 0.0 0.8 0.0 2.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 4.2 1.2 23.3 1.2 39.4 0.4 1.2 3.5 0.1 11.0 1.3 0.6 0.3 10.9 1.2 0.0 0.4 5.7 5.1 14.9 11.7 24.8 9.9 8.4 20.1 8.4 15.2 4.9 7.1 18.0 95.3 22.4 7.7 59.1 16.3 11.1 81.7 7.7 8.6 32.6 12.6 16.8 35.1 42.9 7.1 9.2 0.0 0.1 51.2 0.7 1.9 1.9 21.1 1.7 41.3 49.5 7.2 18.1 134.8 0.9 0.2 59.8 1.1 3.8 14.5 38.2 65.7 50.9 0.8 0.0 125.9 3.7 8.2 27.0 5.3 27.7 89.8 32.1 7.2 65.6 7.6 20.2 119.4 45.8 43.4 0.3 0.1 92.2 17.7 38.6 28.8 6.6 6.8 1.9 105.2 163.9 75.3 0.4 9.9 1.8 6.8 0.3 27.8 0.2 3.5 9.4 ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043848 Approved Nucleoplasm No No "Cluster 2: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA043848: AB_10961146" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (1.31e-1)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (6.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.81e-1)" "unprognostic (6.54e-3)" "unprognostic (1.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.66e-2)" "unprognostic (9.32e-3)" 10.2 15.1 1.2 2.6 1.2 2.1 11.3 1.1 3.5 15.6 0.7 10.4 4.7 15.6 8.5 13.3 12.6 1.7 10.6 1.2 0.9 11.9 10.1 12.0 1.1 2.1 1.3 14.9 12.2 11.6 10.5 2.3 1.4 12.1 4.2 5.7 12.0 3.8 8.6 19.2 11.6 3.0 1.5 13.7 11.8 6.1 1.0 5.3 15.1 3.9 3.9 12.0 13.2 1.4 0.3 0.3 8.5 4.4 8.3 3.3 3.5 7.5 7.3 7.1 4.6 0.1 1.9 1.9 5.6 12.5 9.1 0.6 0.3 4.6 5.2 11.7 2.8 7.5 4.4 4.1 0.0 0.0 2.8 10.8 10.0 0.3 2.6 9.8 0.7 6.3 2.9 7.8 2.6 4.7 4.6 6.7 0.0 0.4 2.2 0.5 0.1 4.2 6.3 0.4 9.7 0.6 0.7 0.4 4.3 5.0 0.7 0.4 10.7 3.9 4.5 0.2 0.2 4.3 4.5 1.9 5.6 1.1 4.3 0.8 0.2 0.8 0.3 0.3 0.1 0.5 0.4 0.2 0.2 0.3 0.7 0.1 0.3 0.1 0.2 0.4 0.1 0.2 1.2 1.2 1.1 3.5 1.2 0.9 2.1 1.3 1.4 1.5 1.0 1.4 9.4 0.0 5.0 2.6 7.3 6.4 16.3 6.0 8.6 20.1 9.9 7.6 4.3 4.3 4.9 7.3 8.4 6.3 3.3 9.8 23.5 11.0 1.6 8.3 5.2 7.7 7.7 4.0 2.8 7.1 4.6 6.7 5.6 6.9 3.8 6.5 7.9 2.0 5.3 20.2 2.8 8.7 12.2 4.4 4.0 1.8 9.3 5.3 1.8 3.7 12.1 18.2 8.2 3.5 2.6 6.5 8.6 6.4 4.0 10.9 7.6 8.3 6.0 21.2 13.1 10.0 7.6 2.2 2.0 8.1 7.4 10.1 4.9 8.0 5.8 11.8 ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 23.9;testis: 55.3" "Group enriched" "Detected in many" 5 "Early spermatids: 165.2;Late spermatids: 195.1;Spermatocytes: 198.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" Mitochondria "HPA050928: AB_2681277, HPA065062: AB_2732728" "unprognostic (8.01e-2)" "unprognostic (2.01e-2)" "unprognostic (9.61e-2)" "unprognostic (8.01e-2)" "unprognostic (1.97e-3)" "unprognostic (6.00e-2)" "unprognostic (8.94e-2)" "unprognostic (1.20e-2)" "unprognostic (3.71e-3)" "unprognostic (3.22e-2)" "unprognostic (1.09e-3)" "unprognostic (2.26e-1)" "prognostic favorable (4.63e-13)" "unprognostic (4.69e-3)" "unprognostic (7.37e-2)" "unprognostic (3.12e-1)" "unprognostic (1.81e-1)" 1.1 2.5 2.5 0.6 2.7 0.4 1.7 2.8 2.9 1.8 5.1 2.7 3.1 1.3 23.9 1.3 11.0 1.6 5.2 2.4 2.9 5.5 8.4 2.5 0.2 3.1 3.7 0.6 5.1 6.9 6.1 0.8 2.9 1.3 2.4 2.6 2.9 3.4 4.7 1.6 2.4 1.0 2.8 0.8 1.6 55.3 2.9 2.3 7.0 1.5 0.5 1.4 0.6 3.3 3.8 2.8 0.3 3.3 0.2 0.0 1.8 0.3 1.1 1.4 0.8 4.8 6.9 3.3 2.6 0.4 2.6 1.0 0.0 0.0 1.2 3.9 0.3 0.6 1.0 2.3 2.5 0.0 1.8 0.3 0.4 1.6 0.0 1.7 1.1 0.2 5.8 1.0 0.7 0.6 0.4 0.3 0.7 2.4 1.8 0.0 0.2 0.7 4.3 0.3 5.7 1.3 2.4 2.0 1.5 0.6 2.9 0.9 0.7 0.9 0.9 1.0 0.8 4.0 4.9 1.1 1.4 0.4 0.6 0.3 0.0 0.2 0.6 0.0 0.1 0.4 0.3 0.1 0.1 0.2 0.1 0.1 0.1 1.2 0.1 0.2 0.9 0.1 2.5 2.7 2.8 2.9 2.4 2.9 3.1 3.7 2.9 2.8 2.9 3.3 0.8 6.4 9.7 2.0 0.9 1.8 1.9 1.3 4.6 4.5 7.9 5.1 7.0 2.8 6.6 11.0 10.4 2.3 1.6 2.5 3.9 4.6 165.2 21.0 2.1 2.0 5.3 0.4 2.4 1.4 1.1 2.5 1.1 1.9 1.3 1.1 2.9 4.7 1.7 11.8 2.1 2.3 0.0 1.0 0.7 195.1 3.1 1.0 3.6 1.0 0.9 3.0 8.2 0.5 1.0 1.6 0.6 2.6 0.6 2.8 4.2 7.4 32.5 8.5 6.6 5.2 2.0 198.5 5.5 1.9 0.9 5.1 0.9 2.3 3.9 1.3 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 ZDHHC4 "FLJ10479, ZNF374" ENSG00000136247 "Zinc finger DHHC-type palmitoyltransferase 4" Q9NPG8 7 6577434-6589374 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032124 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA032124: AB_10610699" "unprognostic (1.07e-1)" "prognostic unfavorable (9.35e-4)" "unprognostic (6.82e-2)" "unprognostic (8.36e-2)" "unprognostic (3.66e-1)" "prognostic unfavorable (3.95e-6)" "unprognostic (9.80e-2)" "unprognostic (1.40e-1)" "unprognostic (2.37e-1)" "unprognostic (4.60e-2)" "unprognostic (1.52e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.18e-7)" "unprognostic (8.75e-2)" "unprognostic (9.41e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (8.94e-4)" 25.9 31.0 17.5 16.2 19.4 18.8 24.3 19.4 18.8 24.4 21.1 38.2 19.1 28.0 34.2 19.5 31.0 23.3 26.5 17.8 21.1 33.6 35.7 21.9 20.6 19.5 20.9 27.6 37.9 33.0 23.9 18.5 20.5 25.3 20.8 19.3 32.2 25.5 54.5 13.5 22.5 24.6 19.1 17.9 32.9 33.8 20.9 18.6 36.8 43.7 19.4 29.2 18.7 19.6 50.7 35.0 11.7 68.8 60.8 41.4 52.4 26.2 6.5 31.2 44.3 44.3 69.7 29.9 40.1 51.3 66.2 44.2 40.8 25.7 33.2 16.8 24.0 31.4 37.8 48.6 47.8 39.8 36.6 45.2 37.6 24.1 0.0 40.8 27.9 51.8 72.4 40.3 43.5 59.2 22.1 39.6 59.4 45.0 28.1 29.4 57.5 40.3 25.9 43.7 26.9 68.7 35.5 11.8 51.7 60.4 43.1 45.8 18.7 40.6 54.9 39.2 39.3 62.1 58.7 66.7 21.6 50.0 56.5 56.3 25.0 44.8 24.1 31.9 24.8 38.8 25.1 27.3 28.1 36.0 31.4 31.1 2.9 28.7 26.5 113.9 24.5 29.3 17.5 19.4 19.4 18.8 17.8 21.1 19.5 20.9 20.5 19.1 20.9 19.6 11.7 38.5 20.1 2.9 23.3 11.3 46.5 63.4 24.5 30.2 42.1 34.7 4.4 57.2 42.4 35.0 10.4 69.0 46.1 12.1 86.1 60.5 3.0 24.1 22.1 14.3 32.4 26.5 4.6 66.4 69.4 26.0 20.9 20.3 10.2 25.9 25.0 47.3 55.3 21.9 5.4 21.2 42.7 36.5 18.2 3.5 18.0 24.8 21.4 2.8 35.3 71.8 28.8 5.0 6.7 54.6 21.4 32.7 34.2 39.5 27.2 71.9 32.5 24.6 13.1 20.9 25.6 70.2 69.7 19.2 9.2 48.8 19.0 40.6 27.5 39.5 ZFAND3 "FLJ13222, TEX27" ENSG00000156639 "Zinc finger AN1-type containing 3" Q9H8U3 6 37819727-38154624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 821.8;Late spermatids: 3021.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016755 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA016755: AB_1859011" "unprognostic (3.32e-1)" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" "unprognostic (2.89e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.36e-2)" "unprognostic (9.30e-2)" "unprognostic (1.48e-2)" "unprognostic (9.60e-3)" "unprognostic (1.01e-1)" "unprognostic (2.94e-1)" "unprognostic (7.41e-2)" "unprognostic (4.33e-1)" 44.2 42.3 36.6 31.7 38.0 42.6 36.4 36.8 36.4 42.6 33.2 50.3 39.3 41.2 35.3 37.4 33.4 36.3 51.1 37.0 41.4 47.7 53.3 37.8 28.1 46.2 40.8 32.3 39.0 56.6 33.8 48.8 41.5 35.3 32.1 39.4 32.8 46.1 137.8 33.8 39.5 46.9 39.2 31.6 42.0 113.0 38.2 39.7 52.0 67.3 29.3 49.3 31.2 42.9 59.1 33.8 116.8 82.8 72.4 75.9 42.5 88.6 115.6 87.3 92.8 68.4 33.4 24.6 71.8 106.8 96.2 39.5 48.3 73.4 122.3 102.2 30.6 75.6 17.3 65.3 171.0 29.5 59.4 96.1 93.7 91.7 157.0 101.6 76.8 56.9 37.3 48.1 68.4 50.6 50.2 27.0 33.4 84.5 38.4 52.4 48.4 29.6 79.5 94.0 74.2 63.2 54.6 43.6 151.5 98.1 70.2 61.5 81.5 87.2 66.2 47.5 58.8 47.3 47.7 74.2 32.4 47.1 91.9 0.5 1.7 6.1 1.5 1.7 1.1 1.3 1.1 1.2 0.9 1.9 0.9 1.5 6.0 1.6 1.3 2.9 1.5 0.9 36.6 38.0 36.8 36.4 37.0 41.4 46.2 40.8 41.5 39.2 38.2 42.9 25.4 22.4 11.5 241.0 27.0 27.3 30.9 20.0 52.9 25.8 19.8 19.4 23.0 25.8 11.6 47.8 22.9 35.0 23.2 55.2 74.3 27.3 821.8 25.4 26.6 28.1 16.2 22.5 332.7 29.3 33.1 27.2 31.6 33.2 5.1 33.9 27.5 48.8 33.8 30.3 262.9 30.5 6.1 43.7 44.3 3021.1 38.8 49.2 14.2 283.9 32.9 47.4 34.0 276.0 316.4 38.9 29.1 55.3 28.3 52.3 57.6 38.2 17.2 21.6 32.9 32.9 31.2 63.5 54.1 41.3 30.1 86.1 31.2 21.1 21.5 61.2 ZFAND6 "AWP1, ZA20D3, ZFAND5B" ENSG00000086666 "Zinc finger AN1-type containing 6" Q6FIF0 15 80059568-80138393 "Predicted intracellular proteins" "Apoptosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 496.7;Late spermatids: 598.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034845, HPA052746, HPA077824" Uncertain Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA034845: AB_10671234, HPA052746: , HPA077824: " "unprognostic (2.04e-1)" "unprognostic (2.25e-2)" "unprognostic (3.26e-1)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (3.70e-2)" "unprognostic (4.26e-2)" "unprognostic (1.03e-1)" "unprognostic (4.91e-2)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (6.48e-3)" "unprognostic (4.90e-3)" "unprognostic (1.22e-1)" "unprognostic (1.45e-1)" "unprognostic (1.55e-1)" "prognostic favorable (8.20e-4)" 63.2 70.2 41.3 48.4 43.1 79.9 65.4 54.5 48.8 47.8 48.7 61.5 54.8 58.2 66.2 54.9 54.9 49.8 90.5 42.1 50.1 76.3 123.5 55.7 73.2 50.6 46.4 40.8 42.1 60.6 41.2 50.6 47.7 56.3 61.1 74.2 52.9 50.6 128.5 44.0 53.9 59.8 53.7 60.9 59.6 135.9 44.0 50.9 100.9 109.8 75.5 55.2 43.1 57.2 78.9 161.0 116.9 67.3 118.0 93.4 110.3 91.7 127.2 78.7 107.0 56.6 133.6 87.5 115.7 94.3 76.6 63.1 125.9 92.3 83.8 52.8 107.2 207.1 72.7 78.5 138.2 74.7 131.9 83.3 117.8 87.3 117.7 108.3 120.0 74.4 84.5 66.8 87.3 83.3 59.5 74.0 73.6 70.3 53.4 48.1 102.6 200.8 196.3 129.4 23.9 68.8 79.2 91.0 238.4 144.5 89.1 106.7 111.5 82.1 66.5 53.2 89.8 88.9 189.1 102.6 85.0 127.1 58.6 505.1 90.0 290.1 93.6 118.9 82.5 226.4 84.7 91.2 103.1 174.4 88.2 98.4 216.3 85.0 167.1 89.5 91.2 135.7 41.3 43.1 54.5 48.8 42.1 50.1 50.6 46.4 47.7 53.7 44.0 57.2 60.5 54.5 86.8 76.0 122.5 149.5 141.3 236.1 46.7 40.3 96.2 60.1 92.7 85.8 147.8 75.4 41.7 125.3 101.1 95.9 199.6 103.7 496.7 102.0 57.0 75.0 82.6 97.2 18.1 98.3 130.8 75.0 69.8 135.3 105.1 57.0 72.8 154.6 144.2 32.0 27.7 88.6 203.4 96.1 173.5 598.2 53.1 109.8 124.5 78.7 167.2 101.3 91.6 61.9 73.9 126.5 107.6 62.8 92.7 174.1 64.8 278.8 168.3 89.9 92.1 70.0 98.6 230.6 173.3 62.8 169.3 392.8 87.0 67.6 67.3 183.4 ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA055357: AB_2682793" "unprognostic (4.36e-3)" "unprognostic (6.73e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (8.73e-3)" "unprognostic (5.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (6.00e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.76e-2)" 28.2 14.8 24.5 12.1 24.3 13.5 18.7 27.0 28.1 20.8 21.3 15.6 18.4 17.4 15.2 37.0 18.5 15.1 15.2 23.3 31.9 22.9 39.5 14.4 12.6 25.4 27.7 20.8 17.2 22.8 12.7 14.3 26.5 17.9 14.8 35.0 17.4 18.6 15.5 27.8 19.3 19.2 23.1 15.8 14.8 10.1 24.1 19.8 37.7 19.4 15.0 19.8 17.9 29.4 29.7 13.2 18.0 21.3 34.3 28.3 11.6 35.3 19.6 25.6 29.6 23.5 12.4 44.7 46.1 42.8 11.4 19.6 51.3 32.5 32.4 89.5 26.5 72.6 29.1 14.2 23.3 26.9 33.3 21.4 36.9 35.1 30.0 21.9 20.5 21.2 86.0 34.1 38.3 89.7 62.0 12.1 4.8 62.1 27.7 31.3 16.2 32.0 22.9 66.0 86.3 32.1 40.3 113.6 14.1 10.5 45.4 30.6 19.3 40.1 53.4 32.6 23.8 32.1 95.1 49.6 27.2 49.7 11.2 1.5 3.6 3.6 3.8 6.4 4.8 3.3 4.8 3.5 4.9 3.9 4.5 4.8 1.3 6.5 14.0 2.7 5.7 2.9 24.5 24.3 27.0 28.1 23.3 31.9 25.4 27.7 26.5 23.1 24.1 29.4 35.0 25.6 25.7 0.0 15.7 37.1 28.0 19.7 47.3 46.3 28.8 27.1 30.7 25.8 26.8 20.2 47.9 10.4 22.8 33.5 31.3 16.6 10.9 13.0 52.5 30.8 43.3 19.8 0.0 22.3 6.6 33.0 19.4 13.8 28.5 19.1 28.9 71.5 15.0 146.4 0.0 23.1 14.2 24.2 19.0 21.7 46.6 19.4 26.6 0.0 20.5 46.3 27.8 0.0 0.0 16.7 25.8 64.3 15.3 21.2 35.8 33.2 21.4 34.3 39.5 34.4 38.0 38.5 27.6 84.4 62.5 9.6 20.0 27.0 22.8 29.2 ZMAT5 "SNRNP20, ZC3H19" ENSG00000100319 "Zinc finger matrin-type 5" Q9UDW3 22 29730956-29767011 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004858 Approved Supported Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004858: AB_1080657" "unprognostic (2.14e-1)" "unprognostic (8.03e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-3)" "unprognostic (6.04e-3)" "unprognostic (5.69e-2)" "unprognostic (5.75e-2)" "unprognostic (3.71e-2)" "unprognostic (2.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.62e-1)" "unprognostic (4.10e-2)" 14.3 26.0 25.8 10.6 26.4 14.2 14.5 26.5 34.9 17.1 25.9 19.6 12.2 18.0 19.8 21.1 20.5 10.0 25.5 25.3 26.0 21.3 26.8 13.7 15.0 27.5 26.5 16.2 20.4 23.0 10.6 8.4 25.5 19.2 7.2 7.8 18.2 16.6 37.1 18.1 14.4 13.8 26.0 19.9 20.1 10.6 27.2 17.8 19.1 24.5 12.2 19.0 15.8 26.8 17.9 22.1 19.3 37.5 23.7 26.2 8.7 19.4 23.9 28.5 34.7 19.4 11.0 12.2 18.9 20.8 22.0 16.5 16.5 19.9 18.6 39.2 36.3 46.9 10.8 36.3 43.8 21.6 14.8 22.7 30.2 36.5 22.2 24.2 30.4 19.0 12.3 25.9 23.8 26.7 31.0 22.5 7.2 34.7 25.9 37.1 34.2 32.6 22.8 10.9 14.8 27.4 18.1 22.4 27.9 10.9 33.7 30.0 19.4 38.8 19.4 26.4 29.2 24.0 20.5 20.4 29.9 25.6 27.9 48.1 84.6 95.3 46.1 94.6 47.3 61.6 47.7 48.6 73.9 60.3 41.8 49.1 69.5 60.8 94.7 57.6 61.0 65.3 25.8 26.4 26.5 34.9 25.3 26.0 27.5 26.5 25.5 26.0 27.2 26.8 17.0 16.0 20.8 6.2 14.6 9.6 21.0 32.0 10.2 12.7 16.2 22.6 1.4 17.2 20.4 14.7 18.8 21.5 11.3 16.4 33.2 35.3 0.9 13.8 14.3 15.2 14.4 8.6 3.7 27.3 18.1 15.9 13.3 10.4 33.7 13.0 15.0 17.1 45.1 5.0 5.1 19.4 24.4 21.4 17.9 3.0 15.8 22.1 12.4 3.7 27.7 26.0 34.0 6.0 6.5 31.7 18.1 21.8 14.9 12.4 27.8 40.0 19.3 21.4 32.9 15.1 40.0 11.0 22.8 14.0 11.8 14.1 18.0 18.2 14.4 18.9 ZMYND11 BS69 ENSG00000015171 "Zinc finger MYND-type containing 11" Q15326 10 134465-254637 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015816 Supported Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA015816: AB_1845427" "unprognostic (1.96e-1)" "unprognostic (1.66e-1)" "unprognostic (3.00e-1)" "unprognostic (1.12e-1)" "unprognostic (9.12e-2)" "unprognostic (2.33e-2)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (1.80e-2)" "unprognostic (3.73e-2)" "unprognostic (4.47e-3)" "unprognostic (6.35e-2)" "prognostic favorable (4.76e-7)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (9.04e-2)" "unprognostic (1.42e-1)" 41.7 37.1 50.7 26.3 58.8 11.3 45.8 60.0 64.6 47.4 38.5 54.8 29.9 55.0 46.6 42.8 39.8 35.6 58.0 50.7 54.8 51.1 34.9 39.0 26.3 54.1 52.8 55.3 46.4 99.7 27.7 34.8 54.8 52.8 33.8 43.2 46.1 56.0 58.1 33.1 30.9 50.9 52.4 32.7 39.2 33.1 54.1 23.8 88.0 64.7 24.8 46.7 31.1 59.1 64.0 64.6 53.8 42.9 57.3 55.0 33.3 63.0 35.8 43.7 40.5 39.2 62.3 0.1 19.8 78.4 13.8 38.3 28.9 44.2 55.8 25.1 25.1 71.8 33.4 42.3 64.6 19.5 38.8 38.4 60.6 42.3 38.3 56.8 55.6 32.8 19.5 44.7 76.0 75.4 29.3 27.3 17.4 69.3 10.7 28.4 34.4 34.5 58.0 72.7 24.3 44.3 72.3 83.3 34.1 29.4 74.9 37.8 72.2 43.4 15.8 89.2 48.8 37.0 48.4 4.6 44.2 36.1 30.3 15.6 2.3 19.5 11.9 3.5 10.4 5.2 8.3 11.9 3.8 3.1 9.2 9.1 1.0 14.7 1.7 4.5 8.9 5.0 50.7 58.8 60.0 64.6 50.7 54.8 54.1 52.8 54.8 52.4 54.1 59.1 51.2 60.9 51.4 90.8 25.3 25.9 27.0 17.5 34.1 37.5 46.3 33.8 103.0 31.5 31.9 33.1 12.5 15.2 39.4 14.6 50.9 29.3 28.6 27.0 50.3 45.7 25.9 25.0 110.8 31.8 4.6 45.7 27.5 37.1 46.2 42.1 35.3 28.1 14.4 20.2 118.0 26.2 16.2 25.1 14.9 27.1 39.1 21.7 24.9 94.6 13.9 62.5 34.0 128.2 131.5 28.1 14.5 56.1 31.1 44.1 19.1 41.9 23.7 22.0 13.1 56.9 49.8 26.8 25.6 32.2 27.8 12.4 32.6 28.5 22.1 29.8 ZNF114 MGC17986 ENSG00000178150 "Zinc finger protein 114" Q8NC26 19 48270081-48287608 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "thyroid gland: 5.9" "Cell type enhanced" "Detected in some" "Spermatogonia: 4.4;Syncytiotrophoblasts: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 22.2;Hep G2: 27.8;NTERA-2: 13.8;REH: 14.6" "HPA025019, HPA029553" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "HPA025019: AB_1859080, HPA029553: AB_10603005" "unprognostic (1.82e-1)" "unprognostic (1.88e-1)" "unprognostic (5.41e-2)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.29e-4)" "unprognostic (2.67e-1)" "unprognostic (3.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-1)" "unprognostic (4.56e-3)" "unprognostic (5.21e-2)" "unprognostic (1.13e-7)" "unprognostic (9.74e-2)" "unprognostic (2.78e-1)" "unprognostic (9.15e-2)" "unprognostic (1.63e-1)" 0.8 0.4 1.8 0.7 1.6 0.8 0.6 2.1 2.1 1.1 0.8 0.3 0.3 1.1 0.7 0.5 0.9 0.5 0.7 1.7 1.8 0.5 0.2 0.7 0.6 1.4 1.8 0.4 0.8 1.6 0.4 1.4 1.2 0.4 0.2 0.6 0.4 0.5 0.5 1.0 0.1 0.2 0.6 0.6 0.1 0.9 1.8 0.2 5.9 0.4 0.6 0.2 0.3 2.3 3.8 5.9 6.9 0.2 0.0 0.0 22.2 0.4 0.0 2.1 2.8 2.2 5.6 0.0 6.4 0.3 2.4 7.4 9.5 0.1 2.5 0.1 0.6 0.3 1.4 27.8 1.5 3.7 0.5 0.4 0.7 1.1 0.0 0.5 0.1 0.4 0.7 0.0 0.2 10.9 0.3 11.6 13.8 10.3 0.9 14.6 0.0 0.0 0.2 2.7 2.7 3.1 3.7 0.1 3.7 4.2 1.4 7.0 0.9 0.5 2.2 1.7 0.6 0.2 0.2 0.0 0.2 1.8 0.5 1.8 0.3 0.3 0.2 0.2 0.1 0.4 0.2 0.1 0.7 1.2 0.1 0.1 2.0 0.7 0.2 1.0 0.1 0.1 1.8 1.6 2.1 2.1 1.7 1.8 1.4 1.8 1.2 0.6 1.8 2.3 2.3 3.2 1.8 0.7 0.2 0.4 1.3 0.5 0.0 1.2 0.3 0.4 0.5 0.0 2.6 0.0 0.0 2.1 0.2 0.0 1.9 0.5 2.6 3.3 1.6 1.4 0.0 1.3 0.2 0.6 2.5 0.6 0.0 3.9 0.0 0.9 2.2 0.8 1.8 0.0 0.9 0.0 0.0 0.3 2.0 0.8 1.2 0.6 0.0 0.0 0.2 1.3 0.0 2.0 0.2 0.3 0.0 0.7 0.1 0.9 0.0 0.4 0.8 0.7 0.0 0.9 0.6 0.8 4.4 0.0 0.1 15.3 0.5 0.7 0.1 1.1 ZNF148 "BERF-1, BFCOL1, HT-BETA, pHZ-52, ZBP-89, ZFP148" ENSG00000163848 "Zinc finger protein 148" Q9UQR1 3 125225669-125375325 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001656, CAB017486" Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Golgi apparatus" "CAB017486: AB_794260, HPA001656: AB_1079995" "unprognostic (2.40e-1)" "unprognostic (1.12e-2)" "unprognostic (5.03e-2)" "unprognostic (3.94e-2)" "unprognostic (5.94e-3)" "unprognostic (5.66e-2)" "unprognostic (1.24e-2)" "unprognostic (2.36e-1)" "unprognostic (1.69e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (3.63e-2)" "unprognostic (2.72e-1)" 8.9 7.5 5.6 9.4 8.9 7.9 12.1 12.9 7.8 12.6 0.0 10.8 7.6 13.9 10.2 10.3 12.4 9.5 15.5 4.5 16.4 12.9 11.7 10.3 12.3 4.2 6.5 17.4 9.5 15.8 4.7 9.7 4.2 11.1 11.5 13.1 10.0 11.1 11.1 5.8 8.9 13.7 2.3 11.9 9.8 10.5 14.5 16.9 30.0 12.0 14.4 10.6 6.1 8.3 30.6 19.8 21.1 18.9 18.4 19.7 16.0 27.2 31.5 29.9 28.4 19.1 16.6 24.4 18.5 40.3 24.1 24.4 23.2 20.5 42.4 10.9 8.9 30.1 23.3 9.8 13.6 20.9 29.1 16.1 21.0 28.0 29.4 19.7 20.7 17.7 15.0 20.2 22.3 23.9 26.1 7.7 13.6 20.6 16.8 18.6 23.2 13.9 17.1 33.6 18.2 15.3 36.2 18.2 29.7 11.7 22.7 20.8 26.6 22.6 24.1 28.5 17.5 17.4 21.5 36.6 16.9 13.1 21.3 4.4 15.3 32.0 21.8 14.5 22.5 24.5 19.2 20.9 13.0 22.2 27.9 22.0 51.4 33.2 23.4 11.3 19.6 20.1 5.6 8.9 12.9 7.8 4.5 16.4 4.2 6.5 4.2 2.3 14.5 8.3 54.7 93.0 41.3 92.7 56.7 35.6 26.0 36.2 48.9 68.0 37.0 35.7 75.2 24.3 43.0 33.1 39.6 28.7 53.7 34.7 25.4 37.5 82.0 28.8 54.3 51.6 47.9 32.0 166.7 37.4 24.3 44.5 31.1 38.1 50.6 75.7 37.9 41.0 31.1 75.7 170.3 34.4 26.4 37.1 21.2 135.2 48.1 41.2 17.8 143.4 50.1 45.7 59.8 154.3 151.4 33.7 25.6 59.0 35.8 36.6 28.2 43.9 27.5 39.4 32.9 63.4 60.7 24.4 24.2 32.5 38.4 31.6 52.0 42.0 33.6 35.6 ZNF280B "5'OY11.1, SUHW2, ZNF279, ZNF632" ENSG00000275004 "Zinc finger protein 280B" Q86YH2 22 22484421-22508742 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.4" "Group enriched" "Detected in many" 7 "Early spermatids: 135.6;Late spermatids: 99.3;Spermatocytes: 104.2;Spermatogonia: 161.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 20.9;U-2 OS: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059519 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA059519: AB_2684050" "unprognostic (7.32e-2)" "unprognostic (2.99e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (2.65e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-2)" "unprognostic (2.85e-3)" "unprognostic (1.10e-1)" "unprognostic (5.42e-2)" "unprognostic (3.34e-2)" "unprognostic (4.80e-1)" "unprognostic (2.44e-2)" "unprognostic (5.34e-2)" 0.1 1.6 2.4 0.6 2.4 0.3 0.2 1.5 3.2 0.4 0.1 0.3 0.2 1.1 1.0 0.2 0.8 0.4 0.5 2.3 4.0 0.2 0.1 0.2 1.0 2.3 2.8 2.1 0.6 1.2 1.3 0.2 2.3 0.9 0.4 3.3 0.2 1.0 0.3 0.3 0.4 0.8 1.6 0.9 0.4 13.4 3.6 0.8 1.9 0.2 0.9 0.2 0.1 2.2 0.0 2.5 3.2 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.0 1.8 1.1 3.2 3.1 0.1 3.0 0.0 2.8 0.3 0.0 0.0 3.8 4.0 0.6 3.6 2.4 2.5 4.4 1.2 0.0 2.7 0.0 0.5 2.7 3.1 20.9 1.4 1.0 0.0 3.0 1.7 2.4 1.5 0.5 3.0 0.0 0.2 0.8 0.0 2.0 2.2 0.0 0.0 1.1 2.6 0.0 1.9 1.0 4.4 9.8 1.0 0.1 1.7 1.9 1.9 3.0 2.1 0.2 12.9 1.6 2.9 2.6 2.5 4.2 2.8 3.2 2.5 1.5 2.8 3.8 4.5 4.1 5.2 5.4 2.4 2.6 1.8 2.4 2.4 1.5 3.2 2.3 4.0 2.3 2.8 2.3 1.6 3.6 2.2 0.1 0.0 0.6 3.9 5.3 0.1 0.6 0.4 0.0 7.1 0.9 1.3 2.6 2.8 0.6 0.0 4.2 0.3 0.8 0.3 0.0 2.8 135.6 3.4 2.4 1.8 3.0 0.4 12.7 3.7 0.3 1.3 1.1 3.9 0.0 11.4 1.4 0.2 3.0 5.0 14.6 0.7 0.0 0.8 1.9 99.3 2.5 2.6 5.4 1.0 1.9 6.9 5.2 7.5 4.2 2.3 0.1 7.2 0.7 0.8 0.0 4.4 0.0 8.0 6.6 2.3 0.5 104.2 161.7 0.0 0.0 0.3 2.3 17.2 1.6 0.1 ZNF627 FLJ90365 ENSG00000198551 "Zinc finger protein 627" Q7L945 19 11559374-11619161 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA049770, HPA073463" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 10: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm Nucleoli "HPA049770: AB_2680871, HPA073463: AB_2686606" "unprognostic (1.81e-1)" "unprognostic (9.89e-2)" "unprognostic (1.64e-2)" "unprognostic (3.14e-2)" "unprognostic (7.89e-3)" "prognostic favorable (8.12e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (1.83e-3)" "unprognostic (3.17e-2)" "unprognostic (2.03e-1)" "unprognostic (1.67e-2)" "prognostic favorable (6.93e-7)" "unprognostic (2.10e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-1)" "unprognostic (6.39e-3)" 5.6 4.1 5.7 4.3 5.9 7.6 11.1 7.4 6.8 8.3 6.0 5.9 5.7 10.6 8.7 4.6 12.2 5.0 5.2 5.6 5.9 9.6 7.1 6.1 6.8 6.1 6.0 13.1 7.5 8.9 5.8 6.3 5.9 8.0 6.8 8.3 5.9 6.5 4.0 5.5 5.0 6.2 6.2 6.6 6.0 8.0 6.3 9.3 13.1 5.6 5.6 6.4 5.6 7.9 6.0 5.2 15.0 18.8 6.7 6.9 8.5 8.4 10.0 9.5 9.5 3.9 4.0 4.6 8.4 6.6 4.8 5.1 6.0 8.2 10.5 8.3 2.8 12.8 2.8 7.6 12.5 6.9 6.9 8.4 11.6 6.2 14.3 14.5 10.6 10.9 11.9 6.0 12.5 12.3 11.3 6.9 11.3 4.0 10.4 12.6 11.3 6.3 10.8 9.2 20.8 15.5 11.5 6.1 12.6 12.7 11.1 19.6 9.2 10.0 4.8 6.2 5.9 8.6 9.0 4.8 4.6 11.3 8.4 14.2 4.5 7.4 4.6 4.9 5.3 9.0 5.6 5.8 7.2 5.8 7.4 6.7 2.4 7.3 4.8 2.7 3.2 4.2 5.7 5.9 7.4 6.8 5.6 5.9 6.1 6.0 5.9 6.2 6.3 7.9 2.9 12.8 5.9 6.2 11.2 1.3 3.4 4.0 6.2 4.5 6.2 5.8 15.0 7.2 3.1 9.2 4.2 5.2 5.4 3.7 17.6 5.4 7.9 7.0 4.9 4.3 5.3 8.0 4.5 2.6 4.3 4.3 10.2 3.7 1.3 6.1 6.1 6.1 3.2 6.7 4.8 3.2 10.2 4.4 4.4 4.0 5.3 3.1 0.0 3.7 3.2 4.9 3.1 6.6 7.3 4.1 3.1 5.3 6.7 4.9 3.5 7.3 11.6 5.8 0.0 3.1 4.7 15.5 4.4 3.6 2.7 4.7 4.8 3.1 4.3 3.3 ZNRF1 "DKFZp434E229, FLJ14846, nin283" ENSG00000186187 "Zinc and ring finger 1" Q8ND25 16 74999024-75110994 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.4;T-reg: 2.4" "Group enriched" "Detected in many" 4 "granulocytes: 2.4;T-cells: 2.4" "Cell line enhanced" "Detected in all" "HMC-1: 176.9;MOLT-4: 134.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027470 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "HPA027470: AB_10603108" "unprognostic (2.78e-2)" "prognostic favorable (9.90e-4)" "unprognostic (4.45e-3)" "unprognostic (1.51e-1)" "unprognostic (4.34e-2)" "unprognostic (1.18e-2)" "unprognostic (2.51e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-2)" "unprognostic (5.38e-2)" "unprognostic (3.69e-1)" "unprognostic (2.28e-1)" "unprognostic (1.46e-1)" "unprognostic (4.89e-2)" "unprognostic (2.87e-1)" "unprognostic (2.10e-2)" "unprognostic (1.44e-2)" 18.7 16.5 21.1 9.6 22.3 6.7 17.8 9.1 22.8 25.3 19.0 30.6 9.6 22.5 9.5 65.9 18.0 7.5 21.0 23.4 24.5 14.7 17.6 24.1 7.7 19.6 22.5 17.4 11.5 11.8 13.4 11.2 18.6 13.7 12.1 7.4 16.9 7.0 81.2 25.0 15.3 11.4 13.4 4.5 21.0 37.4 30.7 53.2 29.3 30.6 13.3 22.5 26.4 17.5 10.9 15.7 26.7 27.5 27.7 21.4 91.2 13.0 18.3 17.5 17.1 25.4 33.2 2.9 9.9 28.3 16.8 25.5 13.0 17.8 13.9 26.7 7.5 56.7 4.8 47.0 22.0 27.5 176.9 19.5 14.7 18.4 14.9 30.8 29.0 68.3 27.8 8.8 13.7 104.5 134.6 100.6 37.1 31.4 16.7 59.0 10.0 17.4 25.1 30.5 35.4 37.7 20.7 27.0 8.3 21.7 71.6 25.8 19.9 12.0 21.0 21.5 7.9 50.5 55.1 31.6 15.8 30.2 12.6 2.4 0.5 0.4 0.0 0.5 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.5 0.0 2.4 0.1 21.1 22.3 9.1 22.8 23.4 24.5 19.6 22.5 18.6 13.4 30.7 17.5 34.8 9.6 14.4 16.6 1.8 15.9 16.0 11.2 4.6 12.6 24.3 22.4 16.4 18.6 14.0 3.7 52.1 6.4 2.3 25.5 0.0 8.9 25.9 30.7 15.1 30.2 19.8 30.5 45.2 12.7 10.1 15.1 18.3 28.0 36.8 23.7 12.8 14.4 10.4 3.3 42.4 14.0 14.2 7.3 10.9 16.3 6.8 7.3 14.2 33.7 7.6 15.0 0.0 33.7 29.5 20.0 12.1 4.1 1.8 17.2 9.6 6.2 15.1 6.5 0.0 12.4 14.7 13.6 18.7 21.0 19.6 4.5 13.3 16.7 12.7 29.6 ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883572-29057488 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 504.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)" 2.8 7.1 11.3 1.3 11.2 0.3 2.6 8.1 13.8 4.4 1.0 3.9 3.0 5.1 13.4 3.4 4.8 2.1 2.6 12.1 5.5 8.2 6.6 4.3 0.5 13.2 9.2 5.9 3.3 8.7 2.7 5.0 4.2 7.2 3.4 1.1 7.5 7.7 3.8 5.3 2.7 4.6 5.1 1.2 4.4 5.0 13.6 1.3 4.1 1.9 0.6 3.2 3.3 6.2 5.8 13.7 12.5 3.5 2.3 2.6 23.7 3.5 1.7 2.7 2.6 20.8 3.2 0.1 5.4 1.8 4.9 9.8 8.7 5.5 3.3 7.8 8.9 2.3 2.5 46.1 2.0 6.9 2.3 2.7 5.0 4.3 4.3 2.3 2.4 4.1 5.0 3.2 3.9 5.6 0.2 3.5 4.6 7.3 5.4 6.9 8.2 5.3 11.6 8.5 20.6 7.6 6.2 6.1 3.5 3.8 4.1 3.1 2.3 10.3 8.8 8.2 5.8 4.3 6.3 8.1 4.4 3.9 5.5 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 11.3 11.2 8.1 13.8 12.1 5.5 13.2 9.2 4.2 5.1 13.6 6.2 4.2 12.8 23.6 504.1 0.3 12.6 5.2 4.9 15.9 3.7 5.7 9.5 7.5 8.6 5.3 12.9 0.0 28.1 0.5 2.1 1.9 5.0 12.7 8.0 8.0 5.8 8.4 4.0 62.9 2.5 2.5 5.8 5.6 15.5 0.0 5.4 2.2 17.6 3.5 1.7 37.4 9.4 0.0 1.0 3.1 15.0 10.8 0.8 0.0 82.4 0.0 6.0 0.0 54.8 34.4 3.7 2.1 12.8 0.6 9.6 2.4 11.6 4.9 3.9 0.0 16.0 6.6 4.6 3.2 7.8 7.5 7.7 0.7 14.5 12.9 2.8