Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" A2M "CPAMD5, FWP007, S863-7" ENSG00000175899 Alpha-2-macroglobulin P01023 12 9067664-9116229 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 1678.3" "Cell type enhanced" "Detected in many" "Adipocytes: 1319.0;Endothelial cells: 797.7;Hepatic stellate cells: 526.1;Hepatocytes: 910.1;Horizontal cells: 681.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.5" "Lineage enhanced" "Detected in single" "T-cells: 1.5" "Group enriched" "Detected in some" 5 "AF22: 772.0;ASC diff: 223.5;Hep G2: 649.8;SK-MEL-30: 230.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002265, CAB017621" Supported "Secreted to blood" NA NA 1630000000000 170000000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB017621: AB_1118894, HPA002265: AB_1078142" "unprognostic (1.73e-2)" "unprognostic (1.05e-3)" "unprognostic (1.72e-1)" "unprognostic (2.29e-2)" "unprognostic (7.36e-2)" "unprognostic (3.91e-2)" "unprognostic (7.95e-2)" "unprognostic (3.65e-2)" "unprognostic (2.38e-1)" "unprognostic (7.19e-2)" "unprognostic (4.71e-2)" "unprognostic (2.06e-2)" "unprognostic (1.28e-2)" "unprognostic (8.04e-3)" "unprognostic (2.32e-2)" "unprognostic (8.58e-2)" "unprognostic (9.03e-3)" 451.5 182.3 157.5 149.8 158.5 5.6 295.3 169.3 223.5 227.2 163.3 257.0 141.2 306.2 244.1 218.3 228.4 452.4 312.8 149.8 175.0 311.4 1250.0 1678.3 98.2 192.9 167.6 101.7 91.5 153.7 135.3 445.2 193.0 293.8 316.3 129.9 131.8 226.7 147.8 71.5 182.7 520.0 196.2 240.6 171.6 58.9 190.7 53.9 202.7 285.6 59.2 847.0 160.2 192.7 0.3 0.0 772.0 0.0 223.5 16.2 2.0 93.1 25.5 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 10.1 649.8 0.0 0.8 0.8 36.9 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.0 0.2 2.0 3.3 0.0 0.1 1.8 0.9 0.8 0.0 0.3 0.3 0.7 1.8 0.0 230.1 3.2 0.0 0.3 0.3 0.1 6.7 1.5 0.5 0.7 0.3 0.7 0.2 0.5 15.4 0.0 0.1 0.0 1.5 0.0 0.8 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 157.5 158.5 169.3 223.5 149.8 175.0 192.9 167.6 193.0 196.2 190.7 192.7 1319.0 12.8 85.6 5.2 9.0 19.5 2.3 0.0 12.0 5.5 10.8 95.5 106.1 22.8 6.8 1.8 8.4 2.5 8.1 0.0 0.0 0.2 18.8 8.3 54.7 797.7 0.0 45.9 3.2 5.5 2.9 241.3 9.2 14.7 27.8 2.5 526.1 910.1 233.0 681.4 2.9 0.0 0.0 123.1 41.4 36.8 77.3 130.7 23.2 355.1 37.8 6.1 1.0 5.5 4.7 0.2 0.0 141.4 11.2 4.7 0.0 0.3 4.4 21.2 335.2 22.1 328.0 2.7 8.8 8.2 14.1 4.1 13.0 73.3 0.0 3.6 A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 ADCY4 AC4 ENSG00000129467 "Adenylate cyclase 4" Q8NFM4 14 24318349-24335093 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 90.9;Endothelial cells: 74.6;Hepatic stellate cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 2.9" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.9" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 2.9;TIME: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB005070, HPA048344" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB005070: AB_2273639, HPA048344: AB_2680366" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (3.47e-4)" "prognostic favorable (8.20e-4)" "unprognostic (4.06e-1)" "unprognostic (2.82e-3)" "unprognostic (1.75e-4)" "unprognostic (8.58e-2)" "unprognostic (2.51e-2)" "unprognostic (7.88e-2)" "unprognostic (6.77e-2)" "unprognostic (7.87e-2)" "prognostic unfavorable (7.01e-4)" "unprognostic (8.02e-2)" "unprognostic (3.88e-2)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" 18.0 2.6 2.8 2.3 2.2 0.0 16.1 2.2 2.8 9.2 2.0 3.9 0.9 8.8 0.5 3.7 8.2 2.9 16.9 2.0 2.1 10.2 1.4 9.9 1.6 2.7 2.5 2.4 2.3 1.0 1.7 9.9 2.6 5.3 0.7 0.0 3.7 1.4 4.3 4.7 4.5 1.9 2.4 9.9 3.7 1.1 3.0 0.4 7.7 2.8 0.8 5.9 6.7 2.3 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.1 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.8 2.2 2.2 2.8 2.0 2.1 2.7 2.5 2.6 2.4 3.0 2.3 90.9 0.0 1.8 0.3 1.0 3.6 0.4 0.3 3.4 0.0 1.5 1.5 10.6 0.0 0.9 1.8 0.0 0.2 1.6 2.9 0.0 1.2 1.3 0.5 1.1 74.6 1.2 0.4 0.2 3.1 0.1 4.7 7.1 0.6 1.3 0.0 50.3 0.2 1.4 1.7 0.2 7.9 0.0 5.0 3.1 6.9 0.0 1.5 7.2 12.2 2.5 0.9 1.0 0.0 0.0 2.1 3.8 0.0 1.4 0.4 2.4 0.0 1.1 0.2 6.6 1.7 5.7 0.3 0.8 0.6 2.8 0.0 1.6 0.5 2.1 0.2 ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 104.5" "Cell type enhanced" "Detected in many" "Adipocytes: 428.1;Alveolar cells type 1: 291.7;Alveolar cells type 2: 539.9;Endothelial cells: 222.6;Hepatic stellate cells: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 25.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" 69.8 22.8 15.1 6.9 15.0 0.0 46.0 15.0 18.0 10.4 8.6 9.9 5.7 16.0 7.7 7.0 15.0 16.9 51.6 12.8 15.1 58.9 13.0 104.5 8.5 16.6 15.6 6.5 6.4 13.2 6.7 50.6 18.2 8.9 5.7 1.8 5.9 9.2 30.4 7.7 8.5 21.8 13.8 40.5 8.4 3.1 21.6 3.7 32.2 70.2 3.2 11.4 10.0 15.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 74.1 0.0 0.2 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 15.0 15.0 18.0 12.8 15.1 16.6 15.6 18.2 13.8 21.6 15.3 428.1 291.7 539.9 2.0 2.9 0.0 0.2 0.0 2.2 0.0 1.5 2.9 16.2 8.6 89.7 1.8 0.0 0.2 1.1 0.6 11.7 0.2 10.6 0.8 1.2 222.6 0.0 0.0 8.4 0.0 1.1 9.0 2.6 0.4 12.6 0.0 251.3 4.0 0.2 0.0 1.0 0.5 0.0 13.7 0.0 4.8 3.1 2.7 0.0 104.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.6 0.5 0.2 48.1 0.7 98.6 9.6 80.1 0.2 0.9 0.6 0.0 0.3 1.8 15.5 0.1 0.8 ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 73.1" "Group enriched" "Detected in many" 5 "Adipocytes: 559.9;Endothelial cells: 276.0;Hepatic stellate cells: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 101.2;HUVEC TERT2: 330.0;TIME: 379.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" 73.1 8.2 7.7 9.7 8.2 0.7 64.0 8.5 13.8 22.1 7.0 9.3 4.7 16.3 6.2 9.0 12.1 22.4 24.2 8.0 8.0 15.2 14.3 18.0 9.9 9.1 7.7 4.8 4.7 9.7 5.1 22.5 9.1 9.4 6.3 3.0 7.9 8.9 14.2 9.0 8.6 27.6 7.6 39.8 8.0 6.7 9.8 4.6 20.8 23.6 7.1 24.0 10.4 8.4 0.0 0.0 25.7 0.2 7.3 24.7 0.0 7.8 7.7 0.5 0.3 0.8 0.2 0.2 0.6 22.5 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.5 0.7 0.1 25.3 0.0 0.3 17.8 0.4 55.7 0.3 101.2 330.0 0.2 0.4 2.5 7.0 0.0 0.0 1.0 0.4 0.2 0.4 0.2 0.0 0.0 61.1 3.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 379.3 0.2 5.8 2.0 0.0 0.8 0.5 0.1 0.3 0.5 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 7.7 8.2 8.5 13.8 8.0 8.0 9.1 7.7 9.1 7.6 9.8 8.4 559.9 0.0 6.0 0.3 1.2 0.0 0.4 0.0 4.6 0.0 1.8 2.5 7.6 5.7 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.2 45.3 0.8 1.5 276.0 0.0 2.7 1.5 0.2 0.0 10.2 0.0 3.8 0.0 0.0 287.7 3.5 0.6 1.7 1.0 0.0 0.0 19.2 0.0 57.9 0.6 1.5 0.0 72.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.4 1.2 1.3 0.0 0.0 0.0 0.4 0.0 5.1 5.7 7.2 1.8 1.0 0.0 0.0 1.1 5.4 0.0 0.7 AFAP1L1 FLJ36748 ENSG00000157510 "Actin filament associated protein 1 like 1" Q8TED9 5 149271859-149343637 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.6" "Cell type enhanced" "Detected in many" "Adipocytes: 62.4;Cardiomyocytes: 39.3;Early spermatids: 105.4;Endothelial cells: 72.0;Extravillous trophoblasts: 47.1;Hepatic stellate cells: 47.2;Late spermatids: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.6;HUVEC TERT2: 20.8;TIME: 33.9;WM-115: 79.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.91e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.20e-1)" "unprognostic (3.44e-1)" "unprognostic (2.61e-1)" "unprognostic (1.41e-3)" "unprognostic (5.25e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" "unprognostic (4.00e-1)" "unprognostic (9.64e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-3)" "unprognostic (1.97e-1)" "unprognostic (1.88e-1)" "unprognostic (9.88e-2)" 23.9 2.8 1.7 2.1 0.9 0.1 15.2 1.1 1.3 4.2 1.0 3.5 0.8 7.1 0.6 4.3 10.1 4.0 26.1 0.9 1.0 4.1 2.1 13.3 2.3 1.4 1.1 3.3 1.0 6.1 2.4 14.4 1.4 3.3 0.7 1.3 3.4 1.9 31.6 6.0 3.4 3.5 1.1 2.9 2.4 2.3 1.8 3.4 7.4 16.6 0.8 4.6 3.7 0.9 7.0 2.4 0.1 0.3 9.9 2.1 42.6 1.5 5.5 5.4 8.9 0.1 4.1 0.0 3.3 2.5 13.7 1.4 0.8 6.2 2.2 0.0 1.0 1.6 0.9 0.0 5.2 0.0 0.1 7.3 1.0 3.0 11.6 4.3 20.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 1.0 0.0 5.4 0.0 0.0 0.0 3.5 1.1 0.7 1.1 4.4 0.1 14.8 1.5 0.2 0.4 33.9 2.5 7.7 0.1 1.2 0.0 0.0 0.0 0.5 0.1 79.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.7 0.9 1.1 1.3 0.9 1.0 1.4 1.1 1.4 1.1 1.8 0.9 62.4 0.0 1.3 0.3 0.2 1.5 1.4 4.6 0.0 0.3 0.4 0.5 39.3 1.5 4.1 0.0 0.0 14.2 0.2 0.0 0.0 0.3 105.4 0.3 0.4 72.0 0.0 0.0 2.9 0.0 47.1 4.5 0.0 0.2 1.3 0.0 47.2 0.6 2.7 0.0 1.2 0.0 0.0 4.2 1.3 50.4 9.6 0.7 7.2 10.3 0.0 0.5 0.0 2.0 0.3 0.0 0.0 15.8 0.0 4.0 0.0 0.8 6.4 5.3 13.1 4.6 4.0 0.5 4.8 0.3 1.4 6.4 0.5 1.8 0.0 5.4 ARAP3 "CENTD3, DRAG1, FLJ21065" ENSG00000120318 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3" Q8WWN8 5 141653401-141682230 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 33.2;Endothelial cells: 28.3;Hepatic stellate cells: 28.5;Horizontal cells: 38.7;Microglial cells: 15.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.3;neutrophil: 2.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "EFO-21: 39.4;HUVEC TERT2: 74.3;TIME: 53.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042887 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042887: AB_10796681" "unprognostic (1.98e-1)" "unprognostic (4.88e-2)" "unprognostic (9.30e-2)" "unprognostic (1.31e-1)" "unprognostic (5.58e-2)" "unprognostic (5.26e-2)" "unprognostic (3.77e-3)" "unprognostic (9.76e-2)" "unprognostic (3.43e-2)" "unprognostic (1.39e-1)" "unprognostic (4.42e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.59e-6)" "unprognostic (4.96e-2)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" 11.4 4.1 4.6 5.4 4.7 6.2 10.1 5.2 5.4 9.5 1.5 4.5 3.2 7.5 5.4 3.2 7.8 6.7 14.1 3.3 2.9 7.8 2.1 15.8 2.3 4.1 4.4 3.7 2.5 5.3 5.1 11.9 4.4 7.4 2.6 3.9 3.9 5.8 7.0 2.6 4.6 5.9 3.1 7.3 4.3 1.6 6.3 0.7 8.5 9.2 1.2 7.8 7.3 2.9 11.9 7.5 29.4 0.0 1.8 4.5 0.3 7.0 7.9 7.2 9.2 4.7 0.9 0.1 39.4 2.6 11.7 12.8 5.0 16.8 5.5 0.2 2.1 11.0 12.6 0.1 8.2 0.9 0.4 8.3 7.6 3.9 8.9 20.1 74.3 0.0 0.8 0.1 1.0 0.3 0.0 9.5 17.4 3.9 9.4 0.2 2.3 0.0 0.8 5.4 0.5 24.7 15.1 0.8 12.7 10.6 0.4 2.8 53.3 4.8 10.8 1.3 14.7 0.0 0.1 0.1 12.4 12.6 24.3 0.3 0.5 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 0.0 0.4 0.0 0.1 0.2 4.6 4.7 5.2 5.4 3.3 2.9 4.1 4.4 4.4 3.1 6.3 2.9 33.2 3.2 8.6 0.3 0.3 0.5 1.7 3.1 0.0 6.1 0.9 2.2 5.2 0.0 2.6 1.8 0.0 0.1 1.6 1.3 0.0 1.2 0.0 0.7 2.3 28.3 0.0 0.0 2.4 0.7 0.1 2.2 1.1 1.2 1.3 0.0 28.5 0.3 1.3 38.7 3.2 1.3 2.0 4.4 2.1 0.6 0.3 2.2 0.0 15.0 2.7 3.6 2.1 1.5 0.1 4.6 1.8 1.5 1.6 2.8 0.0 0.1 0.9 0.9 0.0 1.2 3.3 0.5 0.9 0.8 0.4 0.1 1.5 0.4 2.7 3.6 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHSY1 "CSS1, KIAA0990" ENSG00000131873 "Chondroitin sulfate synthase 1" Q86X52 15 101175727-101252048 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 216.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "unprognostic (7.28e-2)" "unprognostic (6.39e-2)" "unprognostic (9.24e-2)" "unprognostic (1.55e-1)" "unprognostic (7.60e-2)" "unprognostic (9.51e-3)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (1.77e-1)" "unprognostic (1.32e-2)" "unprognostic (5.97e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (6.33e-5)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" 27.5 18.6 10.3 18.5 9.8 23.0 21.7 9.0 11.8 19.5 14.4 7.7 6.0 17.3 9.5 10.8 14.9 22.7 20.1 9.2 10.3 13.7 10.0 23.6 11.6 14.2 13.8 19.7 7.3 7.4 8.5 46.7 11.9 14.4 8.2 7.0 10.1 11.4 6.5 15.0 7.7 20.0 11.5 13.9 10.4 8.7 12.5 10.5 10.0 7.4 10.3 34.8 14.0 9.8 9.1 11.2 36.8 18.7 18.9 25.0 24.5 21.8 19.2 25.8 26.2 9.7 7.1 22.0 12.7 36.3 16.8 24.7 24.5 27.7 28.2 24.6 12.4 43.4 12.2 11.4 23.3 66.9 42.9 23.2 22.8 22.3 20.1 29.3 30.8 9.7 16.2 216.3 19.7 7.9 9.2 46.3 42.5 17.7 7.9 20.6 36.9 32.8 18.1 17.7 6.4 34.6 23.0 11.1 40.8 29.8 12.6 81.6 26.2 41.9 24.1 20.0 46.5 38.2 94.5 12.7 32.5 62.2 32.0 0.0 1.3 2.9 1.5 0.8 1.7 0.9 0.9 1.6 0.8 1.0 0.5 1.0 4.9 0.7 0.9 0.5 1.8 0.6 10.3 9.8 9.0 11.8 9.2 10.3 14.2 13.8 11.9 11.5 12.5 9.8 55.0 0.0 15.7 27.7 11.4 57.9 20.7 10.1 20.5 10.7 41.9 29.8 9.3 5.7 9.4 16.5 6.2 6.1 14.6 1.6 1.9 5.3 1.2 10.0 33.4 45.8 3.0 12.0 34.2 2.2 28.8 40.0 5.1 13.8 25.9 51.9 60.0 5.4 16.6 38.7 36.1 3.6 10.2 17.8 37.1 2.5 55.0 41.2 26.6 59.0 10.2 9.2 10.3 21.1 24.2 5.5 2.5 47.0 9.3 19.3 1.2 2.4 8.1 7.5 46.0 47.9 53.5 3.9 7.5 10.5 62.5 13.8 15.2 23.0 3.9 10.2 CLEC14A C14orf27 ENSG00000176435 "C-type lectin domain containing 14A" Q86T13 14 38254000-38256093 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Adipocytes: 396.6;Endothelial cells: 272.8;Hepatic stellate cells: 567.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 83.7;HUVEC TERT2: 451.8;TIME: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039468, HPA048119" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus" NA NA 4100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum, Golgi apparatus" "HPA039468: AB_2676524, HPA048119: AB_2680270" "unprognostic (4.02e-1)" "unprognostic (4.26e-2)" "unprognostic (4.20e-3)" "unprognostic (9.44e-2)" "unprognostic (1.35e-1)" "prognostic favorable (4.13e-6)" "unprognostic (2.55e-3)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (5.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-2)" "unprognostic (1.75e-2)" "unprognostic (1.55e-1)" "unprognostic (4.97e-2)" "unprognostic (5.28e-2)" 67.1 9.5 13.6 7.9 13.4 0.1 50.6 13.8 15.2 24.8 10.9 15.2 10.1 31.2 7.6 11.1 22.6 19.0 65.1 11.5 13.3 15.9 9.4 55.5 6.6 15.0 13.9 9.5 7.8 10.5 6.1 25.0 15.4 14.5 7.2 0.8 13.6 9.8 33.2 15.8 18.8 19.8 13.1 16.7 13.8 3.5 14.9 4.6 31.4 43.3 4.2 19.2 16.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 451.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 158.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 13.4 13.8 15.2 11.5 13.3 15.0 13.9 15.4 13.1 14.9 15.6 396.6 0.0 3.2 0.0 0.9 3.4 0.2 0.0 1.8 0.1 1.5 2.5 6.4 1.5 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.2 0.5 272.8 0.0 0.0 0.4 0.2 0.1 31.0 0.0 0.3 1.3 0.1 567.2 2.1 0.4 0.0 0.2 0.0 0.0 6.4 3.1 1.0 0.6 1.1 5.4 15.0 0.0 0.2 0.0 4.0 2.9 0.0 0.0 0.4 1.4 0.2 0.0 0.0 0.0 0.5 0.0 14.1 7.5 1.6 0.9 0.9 3.1 0.1 1.3 6.7 0.0 0.3 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 68.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoli fibrillar center, Cytosol" "HPA007301: AB_1847693" "unprognostic (1.81e-1)" "unprognostic (1.52e-1)" "prognostic favorable (1.14e-4)" "unprognostic (4.21e-3)" "unprognostic (4.54e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (1.05e-1)" "prognostic favorable (8.08e-4)" "unprognostic (1.38e-1)" "unprognostic (1.63e-1)" "unprognostic (9.99e-2)" "unprognostic (5.12e-2)" 14.5 4.8 5.6 10.3 4.6 0.5 11.3 4.4 6.1 11.8 3.1 15.5 7.5 15.2 4.7 19.5 8.4 16.5 6.3 4.4 7.6 9.1 5.6 13.0 6.2 7.3 6.6 9.4 4.6 7.4 3.5 20.2 7.1 8.9 14.8 8.2 7.0 9.2 3.0 15.4 10.5 13.5 5.7 10.6 8.6 5.8 5.9 4.3 8.3 6.9 8.2 15.6 11.8 7.6 21.8 7.9 25.7 12.2 17.0 22.3 8.6 33.6 31.4 21.4 21.1 6.1 10.7 3.4 13.2 25.4 10.5 17.4 16.9 23.2 24.9 7.1 8.1 4.6 13.1 4.9 19.7 1.6 7.8 26.4 14.0 26.5 23.0 24.5 52.7 5.7 4.2 3.0 29.9 6.4 3.0 0.6 16.6 6.1 12.3 5.3 24.0 0.0 32.6 15.9 12.6 13.2 26.0 5.3 13.3 24.5 4.3 1.8 68.5 21.3 24.9 22.0 15.8 0.4 3.1 0.1 22.1 2.0 57.0 0.0 2.6 0.0 0.0 2.1 0.0 0.1 0.0 0.0 8.6 0.3 0.0 0.0 0.1 0.0 0.4 3.7 2.0 0.4 5.6 4.6 4.4 6.1 4.4 7.6 7.3 6.6 7.1 5.7 5.9 7.6 100.4 57.7 22.4 17.6 4.4 38.7 30.2 32.0 24.5 10.2 12.3 9.5 9.7 7.2 41.4 22.0 6.2 17.6 4.6 64.0 3.9 39.1 3.3 29.1 30.7 71.6 8.3 3.6 44.1 21.6 12.8 24.2 14.8 58.5 19.0 17.8 41.7 1.6 13.5 5.0 31.2 27.4 30.5 29.7 131.7 4.0 10.5 40.8 16.0 81.5 30.5 11.0 0.0 30.2 25.1 47.7 52.7 11.3 0.7 25.4 21.7 22.6 17.5 7.9 19.7 20.1 29.2 16.8 16.7 25.0 60.7 25.4 2.7 9.1 24.4 69.3 CYYR1 C21orf95 ENSG00000166265 "Cysteine and tyrosine rich 1" Q96J86 21 26466209-26573286 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 200.0;Endothelial cells: 150.0;Hepatic stellate cells: 79.9;Microglial cells: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 38 "plasmacytoid DC: 31.4" "Lineage enriched" "Detected in single" 82 "dendritic cells: 31.4" "Cell line enhanced" "Detected in some" "AF22: 14.1;NTERA-2: 39.2;PC-3: 11.0;RH-30: 16.6;SCLC-21H: 33.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034921, HPA067685" Uncertain Approved Nucleoplasm NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB034921: AB_2089315, HPA067685: AB_2685887" "unprognostic (5.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.44e-3)" "unprognostic (9.29e-3)" "unprognostic (2.26e-1)" "unprognostic (1.88e-1)" "unprognostic (1.49e-2)" 36.4 46.4 9.7 8.1 9.0 7.8 30.2 8.7 11.4 16.4 8.4 8.4 6.1 19.2 8.1 9.0 12.9 16.1 22.3 8.1 9.4 12.7 4.8 23.7 6.0 9.9 10.5 4.5 5.5 15.5 3.8 36.3 10.6 9.5 6.6 0.9 6.8 11.4 15.1 8.2 9.6 23.6 9.6 32.5 7.7 1.9 10.8 6.0 14.1 31.8 4.6 12.6 9.5 9.4 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 7.1 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.5 0.0 0.4 0.0 5.6 0.0 0.0 0.0 2.6 0.0 0.0 0.1 39.2 0.0 11.0 0.0 16.6 0.0 1.7 0.0 33.7 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 31.4 0.0 0.1 9.7 9.0 8.7 11.4 8.1 9.4 9.9 10.5 10.6 9.6 10.8 9.4 200.0 0.0 0.6 1.6 1.5 11.7 2.0 10.2 27.3 0.1 14.9 15.0 6.7 0.0 1.7 14.7 0.0 0.1 14.9 0.0 3.9 0.0 0.7 0.4 6.9 150.0 0.0 11.1 1.6 0.0 0.2 8.3 0.0 0.4 0.0 3.7 79.9 0.4 0.3 0.0 4.6 0.0 2.0 3.2 8.0 1.5 2.1 1.4 7.2 58.1 0.7 0.5 0.0 0.0 0.7 0.1 0.0 0.0 2.5 1.1 0.0 6.8 1.1 0.3 0.0 13.3 4.4 0.2 1.3 4.9 5.4 0.3 1.5 0.4 0.0 0.7 DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 287.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA052923: AB_2681989, HPA055009: AB_2682669" "unprognostic (5.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.03e-1)" "unprognostic (3.48e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.15e-2)" "unprognostic (3.10e-1)" "prognostic unfavorable (1.14e-6)" "unprognostic (9.86e-3)" "unprognostic (1.03e-1)" "unprognostic (4.32e-1)" "unprognostic (1.40e-2)" 45.8 23.5 72.4 23.2 90.5 21.7 36.3 85.0 80.7 36.1 45.5 44.2 5.8 38.5 14.1 17.4 37.5 23.3 58.0 65.1 85.4 25.5 15.7 46.1 16.8 81.5 86.6 30.2 23.2 18.5 20.5 28.8 77.0 24.5 12.9 34.7 19.5 40.0 26.7 17.3 20.2 47.5 74.9 31.4 23.7 15.8 87.3 28.0 22.0 33.7 15.9 40.4 25.1 81.3 18.8 23.3 63.7 56.1 113.0 92.0 61.7 69.2 99.8 85.7 104.5 16.4 13.6 0.0 30.5 129.0 82.4 12.7 64.3 22.5 111.4 73.0 30.9 6.2 32.2 34.5 61.0 34.4 13.9 76.8 11.5 51.1 74.6 59.7 83.8 21.9 33.6 0.3 101.9 11.0 19.4 15.1 19.7 3.2 28.6 34.2 46.1 0.3 41.6 13.4 15.9 32.1 65.8 29.7 27.2 70.4 15.7 24.6 59.2 63.0 41.0 78.7 47.3 1.4 0.4 18.7 63.4 14.1 51.9 4.4 5.0 5.7 0.1 6.3 0.6 1.8 1.3 1.3 4.6 0.2 3.8 1.9 10.8 1.0 9.2 1.1 0.0 1.9 72.4 90.5 85.0 80.7 65.1 85.4 81.5 86.6 77.0 74.9 87.3 81.3 34.1 19.2 14.5 43.8 7.4 21.7 19.3 10.3 10.2 9.7 15.3 13.8 33.2 14.3 8.0 14.7 60.5 15.9 6.4 0.3 0.0 7.3 1.1 26.3 31.8 31.3 6.6 7.8 47.7 6.7 20.1 27.1 3.1 57.8 2.5 11.6 21.4 10.9 21.8 13.5 74.2 2.2 4.1 36.3 63.4 2.0 21.5 48.9 19.6 68.4 41.1 11.6 3.1 136.2 287.1 8.4 1.4 20.7 0.9 32.5 0.1 10.3 4.8 10.5 26.3 34.4 31.6 7.9 12.3 6.3 8.2 11.2 6.3 16.0 0.8 15.0 DIPK2B "CXorf36, DIA1R, FLJ14103" ENSG00000147113 "Divergent protein kinase domain 2B" Q9H7Y0 X 45148373-45200901 "Disease related genes, Predicted secreted proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Adipocytes: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 57 "HUVEC TERT2: 81.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002806 Uncertain "Secreted - unknown location" NA NA 940000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA002806: AB_1078595" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (8.51e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (4.07e-3)" "unprognostic (7.30e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (3.39e-1)" "unprognostic (6.06e-2)" "unprognostic (1.32e-1)" "unprognostic (1.75e-3)" "unprognostic (3.79e-3)" "unprognostic (1.98e-1)" "unprognostic (8.47e-2)" "unprognostic (3.11e-2)" 40.8 5.3 14.4 6.1 15.0 0.8 36.9 11.7 13.9 19.6 7.8 9.1 2.6 20.5 6.9 6.5 18.0 8.8 27.3 11.4 13.1 7.0 1.4 14.1 5.7 14.4 14.2 6.9 3.5 4.6 3.3 40.5 14.1 11.3 3.8 1.4 6.8 7.2 16.6 7.4 7.7 20.7 12.4 3.1 6.3 1.5 14.8 2.7 18.5 16.6 3.4 14.3 13.9 15.4 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 81.7 0.1 0.0 0.5 0.0 0.1 0.0 0.3 0.1 1.4 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.4 15.0 11.7 13.9 11.4 13.1 14.4 14.2 14.1 12.4 14.8 15.4 96.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EFNB2 "EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228" ENSG00000125266 "Ephrin B2" P52799 13 106489745-106535662 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 239.7;Hepatic stellate cells: 187.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 76.5;OE19: 45.5;SH-SY5Y: 42.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008999, CAB009368" Supported Supported Nucleoplasm,Cytosol NA NA 940000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "CAB009368: AB_2095700, HPA008999: AB_1078721" "unprognostic (1.70e-1)" "unprognostic (1.95e-3)" "unprognostic (1.72e-1)" "unprognostic (5.22e-3)" "unprognostic (4.52e-3)" "prognostic unfavorable (3.11e-6)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (2.09e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (8.70e-5)" "unprognostic (1.60e-1)" "unprognostic (1.09e-2)" "unprognostic (1.30e-1)" "unprognostic (3.07e-1)" "unprognostic (4.62e-2)" "unprognostic (2.27e-3)" 20.7 6.1 3.8 4.3 5.9 0.2 17.1 1.3 6.2 11.0 0.0 22.1 7.9 10.2 0.7 12.1 8.8 4.2 15.5 5.5 4.9 11.2 4.8 23.4 3.2 0.1 0.1 7.2 3.9 3.2 6.3 15.4 0.3 12.5 9.9 3.2 14.0 10.6 6.5 17.2 14.4 5.5 0.1 7.4 15.0 5.4 1.6 3.6 11.9 8.0 3.2 6.5 14.1 4.3 23.3 1.8 76.5 0.1 0.2 0.7 0.3 10.8 5.4 8.2 4.7 19.1 28.7 0.0 11.0 2.5 0.6 28.4 2.9 10.9 8.9 0.0 24.3 0.1 6.0 0.0 1.5 6.9 0.6 3.5 19.0 0.4 16.1 4.1 10.4 0.2 0.1 0.0 9.1 3.3 0.2 0.1 4.7 45.5 5.0 21.9 3.3 0.1 11.9 2.5 5.8 42.7 3.6 1.7 0.1 21.4 1.0 0.2 9.6 16.3 0.0 0.5 23.8 0.4 0.0 0.0 34.5 0.4 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 5.9 1.3 6.2 5.5 4.9 0.1 0.1 0.3 0.1 1.6 4.3 239.7 6.4 35.7 38.8 4.4 83.2 52.9 15.4 13.1 10.4 39.8 45.3 8.8 5.7 13.2 25.8 0.0 1.4 8.6 114.6 0.0 6.8 0.4 24.7 69.8 106.5 50.6 0.0 49.3 1.4 3.1 15.4 69.3 42.1 17.8 11.8 187.4 1.3 1.1 6.7 29.7 59.8 26.4 5.8 11.9 1.0 0.3 4.0 32.0 48.7 0.0 89.1 0.0 3.5 13.9 46.3 64.3 0.4 1.0 25.1 15.9 0.2 8.7 3.4 0.0 33.1 22.8 0.7 3.3 41.1 86.0 1.9 7.9 6.4 71.5 72.0 EGFL7 ZNEU1 ENSG00000172889 "EGF like domain multiple 7" Q9UHF1 9 136658856-136672678 "Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 806.1;Endothelial cells: 436.5;Hepatic stellate cells: 511.5;Hofbauer cells: 290.3;Spermatogonia: 179.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.1;eosinophil: 3.5;intermediate monocyte: 6.2;non-classical monocyte: 5.5;plasmacytoid DC: 5.9" "Group enriched" "Detected in many" 20 "dendritic cells: 5.9;granulocytes: 3.5;monocytes: 6.2" "Cell line enhanced" "Detected in many" "EFO-21: 183.9;HUVEC TERT2: 329.0;RPMI-8226: 136.8;TIME: 312.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050716 Approved "Secreted to extracellular matrix" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA050716: AB_2732562" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (9.76e-3)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.31e-3)" "unprognostic (4.39e-2)" "unprognostic (1.14e-3)" "unprognostic (6.35e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (5.69e-2)" "unprognostic (1.74e-1)" "unprognostic (4.09e-2)" "unprognostic (4.49e-2)" 195.6 50.2 108.8 13.4 90.4 14.4 192.3 85.0 144.3 112.9 74.4 49.1 13.4 104.3 9.8 39.8 98.5 27.4 243.3 89.8 86.5 144.3 56.1 204.2 20.8 102.0 96.9 37.8 28.2 18.5 51.3 181.6 100.9 74.9 3.5 1.0 39.4 13.2 60.5 47.8 51.4 13.4 89.9 191.7 40.7 43.3 111.7 5.6 105.5 25.2 2.9 87.5 86.3 85.2 0.1 45.7 14.6 52.7 1.2 1.0 33.4 12.9 2.3 7.3 2.3 16.2 42.4 0.3 183.9 4.3 11.9 6.5 3.7 8.3 0.3 77.2 14.1 28.8 3.4 1.3 11.4 0.0 40.1 1.5 3.2 3.7 0.0 2.5 329.0 2.1 104.9 0.1 2.5 83.5 0.5 0.7 21.1 64.3 2.6 91.4 5.9 136.8 4.6 1.1 9.3 31.0 6.3 5.9 12.2 4.2 15.5 43.6 312.6 1.8 37.2 4.4 2.5 0.4 0.1 0.5 0.2 0.1 38.4 0.0 2.1 3.5 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.8 0.2 5.5 5.9 0.0 2.4 108.8 90.4 85.0 144.3 89.8 86.5 102.0 96.9 100.9 89.9 111.7 85.2 806.1 0.0 26.5 2.3 6.2 11.9 5.6 5.5 9.6 2.0 5.9 6.7 23.7 5.7 4.2 3.7 0.0 3.1 5.9 1.4 7.9 19.4 2.7 1.4 3.4 436.5 1.2 58.9 15.0 2.0 17.8 18.5 0.5 1.9 20.3 2.0 511.5 20.5 290.3 3.3 10.1 4.6 2.0 24.5 14.2 9.2 8.7 18.7 19.6 102.1 1.2 1.9 0.0 3.5 1.8 5.8 3.7 6.0 4.0 19.1 22.5 25.2 0.2 2.3 13.1 13.0 18.4 18.9 179.8 2.7 9.5 6.0 2.9 4.8 0.5 3.5 ELF2 "EU32, NERF, NERF-1A, NERF-1B, NERF-2" ENSG00000109381 "E74 like ETS transcription factor 2" Q15723 4 139028112-139177218 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 279.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006057, HPA071166" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Nuclear bodies" "HPA006057: AB_1078733, HPA071166: AB_2686351" "unprognostic (7.21e-2)" "unprognostic (3.84e-2)" "unprognostic (7.41e-2)" "unprognostic (3.72e-2)" "unprognostic (2.29e-1)" "unprognostic (2.80e-2)" "unprognostic (1.49e-1)" "unprognostic (2.43e-2)" "unprognostic (7.05e-3)" "unprognostic (1.67e-1)" "unprognostic (5.73e-2)" "unprognostic (2.21e-2)" "unprognostic (2.48e-2)" "unprognostic (3.65e-1)" "unprognostic (3.47e-1)" "unprognostic (1.31e-1)" "unprognostic (4.97e-3)" 23.7 14.2 12.1 15.2 17.3 47.3 24.5 19.2 16.1 21.8 9.6 24.6 15.0 24.7 18.5 17.3 20.7 17.8 20.1 11.1 15.6 15.5 20.4 19.0 19.9 15.6 14.9 28.2 16.7 20.0 22.6 26.8 15.9 21.5 19.2 30.7 21.4 21.7 36.0 23.2 17.6 23.0 13.2 19.6 17.4 37.4 14.5 32.8 23.0 33.6 21.4 19.2 18.4 20.2 15.9 11.3 27.9 21.4 28.2 31.7 26.9 18.4 31.8 19.6 21.8 22.2 31.2 32.3 18.5 25.7 10.4 16.8 41.2 26.3 20.5 20.2 18.6 28.5 26.4 20.0 20.7 32.1 22.1 31.1 24.8 19.3 23.3 25.7 29.5 18.0 46.8 18.4 17.7 27.8 37.8 28.6 17.0 36.4 13.1 36.0 36.8 30.1 25.1 27.2 28.4 32.6 23.1 28.5 17.6 32.4 19.7 38.5 25.0 18.3 15.9 16.7 12.4 40.8 48.6 28.3 13.5 32.4 17.2 13.3 8.3 14.1 12.0 7.2 13.2 17.5 11.8 10.8 9.9 19.3 14.6 13.5 9.1 12.9 7.9 18.0 9.4 5.3 12.1 17.3 19.2 16.1 11.1 15.6 15.6 14.9 15.9 13.2 14.5 20.2 103.0 48.1 22.5 64.0 57.6 53.2 41.1 36.1 120.1 42.0 50.3 40.4 37.0 40.0 39.1 40.5 75.0 32.6 71.9 31.0 43.0 26.4 26.0 60.0 54.3 67.1 47.3 43.5 73.6 24.2 32.3 63.7 35.7 56.3 34.8 44.0 53.2 46.9 22.2 67.3 75.3 38.1 42.7 52.2 40.1 24.6 52.5 59.5 30.2 98.4 49.2 37.3 77.2 83.9 279.4 24.1 33.5 38.0 51.0 52.6 35.9 23.1 48.2 57.7 39.5 81.4 59.2 59.7 42.0 79.0 47.6 23.7 50.7 33.6 27.7 39.6 EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 230.6" "Group enriched" "Detected in many" 7 "Alveolar cells type 1: 4163.5;Suprabasal keratinocytes: 1174.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MCF7: 268.1;RT4: 182.0;SK-BR-3: 256.2;T-47d: 156.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 42: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA014711: AB_1848147, HPA070816: " "unprognostic (1.75e-1)" "unprognostic (4.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.82e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (9.27e-2)" "unprognostic (8.90e-2)" "unprognostic (2.41e-2)" "unprognostic (4.40e-1)" "unprognostic (1.86e-1)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (2.85e-8)" "unprognostic (9.54e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (9.52e-2)" 56.8 9.7 15.5 12.4 15.5 0.7 49.5 14.8 17.1 51.0 18.6 48.0 15.5 25.9 45.5 152.1 35.5 17.7 64.1 13.6 15.6 20.3 83.2 230.6 5.7 16.1 16.8 54.9 13.7 32.8 13.3 23.0 16.0 38.8 34.1 2.0 39.2 17.3 22.5 140.6 28.3 22.3 15.2 16.0 39.1 7.2 18.8 5.3 27.7 25.4 32.8 39.6 72.9 15.7 28.7 39.1 15.9 18.9 35.0 30.0 31.3 40.0 36.8 23.9 35.7 128.5 98.2 0.2 12.6 48.4 17.2 123.9 41.1 49.8 31.3 0.1 26.1 0.1 76.6 72.1 6.1 0.2 0.4 18.4 13.1 31.9 3.2 5.4 10.1 0.1 9.6 2.6 66.9 268.1 0.4 0.6 18.3 46.4 9.5 7.5 18.2 61.7 5.5 182.0 22.0 25.0 49.6 256.2 15.2 45.2 156.6 6.2 5.7 75.5 32.2 25.6 22.7 0.8 1.0 0.2 33.2 0.5 75.7 1.3 0.2 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 1.1 0.3 0.3 0.3 0.2 0.1 15.5 15.5 14.8 17.1 13.6 15.6 16.1 16.8 16.0 15.2 18.8 15.7 239.7 4163.5 368.4 13.1 3.1 356.9 137.9 172.2 111.0 2.3 105.0 94.0 53.1 100.1 255.8 42.3 0.0 74.2 3.1 119.5 0.0 3.8 8.0 78.8 30.9 183.9 104.9 0.0 0.7 67.0 17.8 152.7 46.4 51.9 36.7 68.7 161.0 235.1 10.1 0.0 0.6 207.8 81.4 19.6 136.5 9.3 190.7 17.0 87.2 41.2 33.6 5.7 0.0 22.6 0.6 32.9 158.4 276.1 1.6 86.0 21.0 0.2 142.8 2.2 52.6 256.3 129.3 5.7 12.9 319.5 1174.3 48.0 9.3 73.3 178.5 221.4 ERG "erg-3, p55" ENSG00000157554 "ETS transcription factor ERG" P11308 21 38380027-38661780 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 94.4;Endothelial cells: 105.5;Hepatic stellate cells: 69.9;Microglial cells: 88.1" "Cancer enriched" "Detected in all" 4 "prostate cancer: 18.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 138.3;MOLT-4: 47.7;REH: 151.5;TIME: 113.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018377, HPA046598" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "CAB018377: AB_675518, HPA046598: AB_2679715" "unprognostic (2.14e-1)" "prognostic unfavorable (6.18e-6)" "unprognostic (6.44e-3)" "unprognostic (8.64e-3)" "unprognostic (5.65e-2)" "unprognostic (1.91e-1)" "unprognostic (9.03e-4)" "unprognostic (4.30e-2)" "unprognostic (2.63e-2)" "unprognostic (1.29e-1)" "unprognostic (3.42e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.31e-3)" "unprognostic (3.88e-2)" "unprognostic (2.64e-2)" "unprognostic (5.63e-3)" 24.6 4.1 5.1 7.1 5.5 7.6 20.0 5.0 5.5 10.0 3.0 5.4 3.4 11.6 1.9 5.2 9.1 12.0 12.4 4.5 5.1 12.8 6.1 19.6 7.5 5.9 5.4 4.4 4.9 2.4 2.4 24.3 6.2 7.1 3.4 0.5 3.7 4.3 7.9 4.9 6.5 12.0 4.7 26.6 4.6 1.5 7.0 4.1 10.0 9.9 3.7 9.2 6.9 5.4 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.0 0.0 0.2 22.3 0.0 0.1 0.9 0.0 0.0 138.3 0.1 0.0 0.0 0.0 1.0 47.7 0.0 0.5 0.0 0.0 151.5 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.0 113.4 0.7 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.1 5.5 5.0 5.5 4.5 5.1 5.9 5.4 6.2 4.7 7.0 5.4 94.4 0.0 3.9 0.3 0.7 3.4 1.7 0.6 3.4 0.0 0.6 4.3 3.8 4.3 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.7 0.4 105.5 0.0 13.5 13.3 0.0 0.0 5.7 0.0 2.1 24.0 4.4 69.9 1.3 0.3 0.0 1.7 0.4 0.0 5.9 3.4 2.1 0.9 0.9 3.6 88.1 0.2 0.0 0.0 7.1 1.4 0.0 0.0 0.0 1.5 1.4 0.0 0.0 0.0 0.1 0.0 2.4 3.7 0.3 1.4 0.5 3.4 0.0 0.6 0.5 0.3 0.6 ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 328.8" "Cell type enhanced" "Detected in many" "Adipocytes: 263.1;dendritic cells: 378.9;Endothelial cells: 190.4;Hepatic stellate cells: 213.8;NK-cells: 399.6;T-cells: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 352.9;JURKAT: 362.3;U-698: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002575, HPA063230" Enhanced Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB002575: AB_563721, HPA063230: AB_2684965" "unprognostic (1.76e-2)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.22e-2)" "unprognostic (3.07e-1)" "unprognostic (2.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.46e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-3)" 101.2 19.2 11.7 145.7 10.4 35.3 65.4 9.8 14.1 35.9 8.9 31.2 26.9 36.5 9.3 21.8 20.2 62.5 43.0 8.9 11.3 30.4 47.6 76.2 277.1 13.1 14.7 27.0 20.1 28.4 7.8 56.3 13.4 17.1 31.4 1.8 16.5 20.7 25.6 18.1 49.3 38.1 11.6 185.8 46.1 8.0 15.2 328.8 39.8 42.3 250.2 67.9 19.2 11.3 87.7 15.7 72.8 0.3 30.7 49.3 0.2 65.7 140.2 80.9 77.3 5.1 91.7 312.1 65.7 109.5 184.7 29.8 7.0 190.0 169.0 66.6 1.1 352.9 6.4 0.3 82.2 36.7 4.0 97.2 15.0 69.6 252.2 46.1 67.9 362.3 0.6 63.3 98.1 0.0 185.7 27.4 27.0 7.9 55.0 50.4 118.7 24.5 64.2 95.6 0.9 5.0 34.5 0.7 73.6 48.5 0.3 17.7 126.1 180.5 57.1 35.5 109.1 46.7 8.9 462.5 32.2 68.0 162.1 51.2 0.1 6.6 20.4 0.3 28.9 12.3 27.0 25.0 0.2 9.2 32.5 26.1 1.1 27.8 1.0 6.2 33.3 9.5 11.7 10.4 9.8 14.1 8.9 11.3 13.1 14.7 13.4 11.6 15.2 11.3 263.1 25.6 26.5 2.9 125.6 114.8 41.0 12.4 1.8 0.0 8.2 7.2 9.0 4.3 24.3 11.0 0.0 0.2 378.9 13.1 0.0 31.9 6.2 26.3 51.0 190.4 15.5 13.7 2.0 22.6 0.5 45.5 17.3 66.2 19.6 1.3 213.8 5.4 7.3 0.0 25.6 15.0 10.2 18.3 48.2 1.5 14.0 12.5 69.4 65.6 16.8 0.2 399.6 55.3 9.5 99.3 6.6 15.4 129.6 26.8 2.2 4.6 5.9 0.2 105.2 55.5 76.6 0.7 1.8 1.5 63.2 0.4 323.2 40.4 5.8 32.6 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FLI1 "EWSR2, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "B-cells: 65.7;Endothelial cells: 84.2;Hepatic stellate cells: 64.6;Kupffer cells: 86.4;Microglial cells: 231.4;monocytes: 68.4;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 113.9;HUVEC TERT2: 60.5;REH: 49.8;TIME: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA065030: , HPA073099: AB_2686572" "unprognostic (1.38e-2)" "unprognostic (7.46e-2)" "unprognostic (6.16e-2)" "unprognostic (3.74e-2)" "unprognostic (6.22e-2)" "unprognostic (4.26e-3)" "unprognostic (1.33e-1)" "unprognostic (8.32e-3)" "unprognostic (2.97e-1)" "unprognostic (9.91e-2)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.79e-2)" "unprognostic (2.07e-2)" "unprognostic (2.62e-1)" "unprognostic (4.79e-2)" 10.2 1.9 3.7 10.9 2.3 12.2 6.0 2.1 2.8 5.7 1.2 3.7 3.2 4.6 1.1 2.8 2.7 6.1 6.2 1.8 2.9 2.1 2.8 10.8 12.3 4.7 2.7 1.2 1.7 3.5 0.7 12.5 4.3 1.9 2.9 0.5 2.2 2.2 2.8 1.7 4.0 5.9 3.5 35.8 4.3 0.9 3.9 17.2 2.9 6.6 10.4 6.7 1.9 2.8 0.2 0.0 5.6 0.0 0.8 1.0 0.1 3.3 9.2 3.8 3.1 0.0 0.0 18.5 31.7 11.1 1.1 0.1 0.8 13.5 4.1 9.0 0.2 113.9 0.5 0.0 6.0 13.7 14.6 0.8 1.1 7.7 17.3 11.1 60.5 25.6 0.0 23.3 0.8 0.0 13.3 8.1 1.8 0.0 3.1 49.8 0.1 19.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.0 0.0 20.4 63.0 0.7 0.0 0.2 3.5 7.3 16.4 16.6 0.1 31.8 5.2 34.5 15.5 24.5 10.1 15.3 11.9 6.8 8.9 8.2 19.1 6.0 3.7 8.2 11.8 12.3 19.1 3.3 11.1 20.1 3.7 2.3 2.1 2.8 1.8 2.9 4.7 2.7 4.3 3.5 3.9 2.8 53.4 6.4 5.3 0.3 65.7 5.1 0.3 1.7 2.2 0.0 0.7 1.3 5.5 5.7 0.1 1.8 0.0 0.4 43.1 0.0 0.0 0.0 0.5 0.4 0.6 84.2 0.0 23.4 0.3 0.0 0.4 5.9 2.0 0.3 22.8 0.0 64.6 1.3 43.2 0.0 1.5 0.1 0.0 86.4 24.7 0.5 1.8 60.3 7.2 231.4 68.4 0.1 93.7 4.0 0.7 0.0 0.0 0.7 56.9 0.3 0.0 0.4 0.8 0.4 6.6 2.1 3.1 0.2 0.1 0.6 4.1 0.3 52.8 0.9 0.2 0.4 GIMAP5 "HIMAP3, IAN4L1, IAN5" ENSG00000196329 "GTPase, IMAP family member 5" Q96F15 7 150722253-150750033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 106.2" "Cell type enhanced" "Detected in some" "Adipocytes: 22.1;Basal keratinocytes: 11.1;Endothelial cells: 29.7;Langerhans cells: 13.9;Suprabasal keratinocytes: 10.7;T-cells: 31.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "MOLT-4: 41.7" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (6.77e-2)" "unprognostic (8.83e-3)" "unprognostic (1.61e-1)" "unprognostic (4.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.34e-3)" "unprognostic (2.21e-3)" "unprognostic (6.42e-2)" "unprognostic (2.12e-1)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (9.87e-2)" "unprognostic (2.77e-3)" "unprognostic (4.13e-1)" "unprognostic (7.15e-3)" "unprognostic (1.86e-1)" "unprognostic (1.47e-2)" 34.4 13.6 13.3 44.8 14.2 5.2 25.5 13.7 16.8 15.9 12.7 16.6 10.6 17.1 8.8 12.4 18.9 17.9 24.2 12.8 13.2 12.7 23.3 39.7 106.2 15.2 14.1 5.9 8.7 9.1 4.1 26.4 14.8 6.6 16.5 0.8 7.2 9.0 12.4 7.2 22.1 30.5 14.2 64.2 15.6 3.5 14.7 25.1 18.3 43.9 66.4 26.7 6.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.3 0.0 1.4 0.0 0.0 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.4 0.0 3.6 70.5 1.1 260.4 106.3 337.2 1.1 436.3 334.0 8.0 0.6 521.5 280.6 8.3 188.3 43.6 1.6 176.9 510.2 13.3 14.2 13.7 16.8 12.8 13.2 15.2 14.1 14.8 14.2 14.7 13.8 22.1 0.0 1.7 0.0 1.4 11.1 0.3 0.0 1.2 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.1 5.8 0.2 0.0 0.0 0.1 0.0 0.1 29.7 0.0 0.4 0.0 0.0 0.4 2.6 0.5 0.1 2.5 0.0 8.9 0.6 3.1 0.0 0.0 0.2 0.0 5.3 13.9 0.1 0.0 7.1 3.6 0.0 2.2 0.0 9.2 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.1 0.1 0.0 0.1 0.0 0.7 3.2 0.2 0.1 0.1 10.7 0.3 31.5 0.1 0.1 0.1 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 IL3RA CD123 ENSG00000185291 "Interleukin 3 receptor subunit alpha" P26951 X 1336616-1382689 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.0;dendritic cells: 137.5;Endothelial cells: 83.2;Langerhans cells: 47.6;monocytes: 72.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 2665.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 2665.0" "Cell line enhanced" "Detected in many" "HDLM-2: 128.8;NB-4: 24.9;RPMI-8226: 54.1" "HPA003539, CAB018374" Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "CAB018374: AB_2233620, HPA003539: AB_1078438" "prognostic favorable (9.78e-4)" "prognostic favorable (4.27e-4)" "unprognostic (8.13e-2)" "unprognostic (9.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.29e-3)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-1)" "unprognostic (3.73e-2)" "unprognostic (5.77e-3)" "unprognostic (1.43e-1)" "unprognostic (1.50e-3)" "unprognostic (9.41e-2)" "unprognostic (2.85e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" 25.2 2.9 7.1 15.8 13.6 25.0 20.6 16.1 11.7 6.4 0.2 8.1 5.5 8.7 1.6 5.4 8.0 11.3 13.0 5.9 8.1 9.2 1.8 25.0 25.1 11.7 10.6 8.8 5.4 3.4 2.8 6.2 11.1 7.0 6.6 22.0 9.5 3.2 12.1 12.7 9.2 12.3 7.5 11.1 6.9 3.5 10.1 4.4 10.3 8.6 13.0 12.4 6.3 20.5 0.2 9.4 3.6 1.3 0.1 0.0 1.1 1.2 0.3 0.0 0.1 0.9 1.5 1.2 7.2 0.2 0.6 9.6 0.0 0.0 0.0 128.8 3.9 0.6 2.1 0.4 0.0 0.8 15.6 0.0 0.0 0.0 0.0 4.1 8.2 0.9 0.3 6.1 0.0 1.4 0.7 24.9 3.1 0.8 0.5 1.4 4.2 54.1 0.0 1.4 0.6 0.4 0.6 0.3 2.8 1.8 1.2 17.8 0.4 0.5 1.5 0.5 0.3 12.5 3.9 1.1 9.8 2.8 0.1 2665.0 5.6 83.9 0.6 31.7 1.0 2.5 0.9 0.5 14.9 8.9 0.7 0.7 4.6 14.2 42.5 628.5 0.5 12.0 7.1 13.6 16.1 11.7 5.9 8.1 11.7 10.6 11.1 7.5 10.1 20.5 79.0 3.2 1.8 11.8 6.8 5.9 0.7 0.9 1.2 2.3 0.5 0.9 2.2 1.5 1.0 0.0 10.4 0.1 137.5 4.7 0.0 0.4 0.2 2.7 1.4 83.2 0.0 3.0 7.3 0.2 0.1 4.3 0.5 1.5 11.4 0.4 24.3 0.7 4.6 0.0 14.3 7.3 0.0 2.8 47.6 0.1 0.3 32.9 8.8 13.1 72.6 0.6 1.0 6.0 18.2 0.1 3.4 0.7 4.0 0.7 0.2 0.0 0.4 3.2 0.0 3.6 3.2 0.1 0.7 0.7 5.5 0.3 1.6 1.3 0.6 2.1 ITGA1 "CD49a, VLA1" ENSG00000213949 "Integrin subunit alpha 1" P56199 5 52787916-52959209 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 36.6" "Cell type enhanced" "Detected in many" "Adipocytes: 264.1;Endothelial cells: 120.5;Hepatocytes: 110.5;Sertoli cells: 98.6;Smooth muscle cells: 143.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 4.5;HHSteC: 4.5;SH-SY5Y: 1.7;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042555 Uncertain NA NA 6300000 "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA042555: AB_10794281" "unprognostic (1.48e-1)" "unprognostic (1.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (9.89e-3)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (1.79e-3)" "unprognostic (1.50e-2)" "unprognostic (2.62e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.13e-3)" "unprognostic (2.06e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-2)" 13.9 22.4 0.6 1.0 0.8 0.0 10.2 0.7 0.9 5.1 0.4 36.6 1.1 16.3 2.5 5.7 9.9 2.2 10.6 0.5 0.8 11.0 17.1 22.1 0.8 0.8 0.8 3.6 3.1 2.1 2.3 5.8 0.8 12.6 2.7 0.1 2.3 7.2 4.6 2.3 12.5 5.8 0.8 27.9 16.6 0.8 0.8 0.2 9.7 2.5 0.4 17.9 5.1 0.9 0.0 0.0 0.3 0.0 1.4 0.4 0.1 0.3 1.3 0.3 0.7 0.7 0.0 0.0 0.1 4.5 0.5 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.3 4.5 0.0 0.0 0.7 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 1.7 0.5 0.0 0.0 0.7 0.0 0.0 0.6 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.7 0.9 0.5 0.8 0.8 0.8 0.8 0.8 0.8 0.9 264.1 54.5 26.8 2.9 1.7 3.2 4.7 1.5 2.8 1.8 3.6 13.8 12.6 5.7 8.7 5.5 2.1 1.5 2.9 5.5 1.9 3.0 21.3 7.7 41.8 120.5 16.4 5.3 3.6 5.4 16.8 40.2 6.1 22.1 10.1 1.0 77.1 110.5 2.2 0.0 19.5 14.0 0.0 7.2 8.2 6.1 9.3 5.6 7.2 63.7 9.1 0.4 0.0 1.5 4.2 19.6 7.7 8.2 2.9 3.2 6.5 15.1 6.3 2.0 98.6 18.6 143.9 0.9 1.1 0.5 3.1 3.4 46.0 13.6 14.0 2.3 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KBTBD2 "BKLHD1, DKFZP566C134" ENSG00000170852 "Kelch repeat and BTB domain containing 2" Q8IY47 7 32868172-32894131 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021133 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli fibrillar center" "HPA021133: AB_1852093" "unprognostic (1.01e-1)" "prognostic unfavorable (1.89e-4)" "unprognostic (3.17e-2)" "unprognostic (9.19e-2)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (3.96e-3)" "unprognostic (1.05e-1)" "unprognostic (2.61e-1)" "unprognostic (2.80e-3)" "unprognostic (5.05e-1)" "unprognostic (6.79e-3)" "unprognostic (3.81e-3)" "unprognostic (1.42e-2)" "unprognostic (8.69e-2)" "unprognostic (2.96e-1)" 26.4 16.4 23.0 21.7 25.2 54.6 20.9 27.3 24.9 17.2 21.4 16.9 15.9 20.8 10.7 16.1 15.6 25.2 20.3 21.0 24.8 15.3 21.5 22.5 25.6 27.2 25.8 16.4 11.8 17.1 15.0 25.8 27.2 16.3 19.6 25.9 14.4 15.0 57.6 16.3 17.6 23.6 26.3 27.0 14.8 18.1 26.5 30.5 18.6 40.3 24.0 22.0 17.3 28.8 38.3 18.8 47.5 23.5 28.1 28.0 17.1 33.4 33.9 31.2 37.6 18.7 28.6 31.9 22.6 34.7 52.3 27.5 24.5 26.2 39.2 12.6 17.6 27.1 30.6 24.4 28.9 29.3 34.2 30.1 26.9 34.0 32.9 28.9 34.9 28.6 50.3 46.2 46.4 31.4 24.3 47.9 38.6 26.5 17.7 23.4 41.6 26.7 27.6 22.3 24.9 46.4 21.5 29.1 38.6 39.6 20.7 49.5 30.5 29.6 38.7 28.3 46.5 37.5 39.3 57.6 28.8 34.9 77.0 14.5 6.4 21.4 10.9 12.2 9.2 7.1 5.4 9.7 5.6 9.8 4.2 6.9 39.2 10.7 14.6 2.9 7.6 4.1 23.0 25.2 27.3 24.9 21.0 24.8 27.2 25.8 27.2 26.3 26.5 28.8 67.2 28.9 23.9 24.5 27.0 40.4 15.7 13.4 44.3 14.6 20.4 15.6 18.4 20.0 22.1 1.8 10.4 6.9 41.4 18.1 0.0 11.8 7.7 21.6 23.1 48.7 14.9 25.2 21.0 12.2 8.7 22.2 17.9 33.8 43.7 20.4 36.8 14.6 13.3 8.4 20.5 14.0 4.1 24.6 23.1 6.2 13.1 32.5 24.9 34.7 13.0 8.7 15.5 29.7 36.8 16.8 10.3 6.0 25.2 17.1 10.5 5.1 7.3 8.9 19.7 26.4 21.1 19.1 8.8 25.9 36.1 7.5 28.4 10.8 11.4 18.5 KL ENSG00000133116 Klotho Q9UEF7 13 33016423-33066143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Glycosidase, Hormone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;kidney: 128.7;parathyroid gland: 135.2" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 123.3" "Group enriched" "Detected in many" 6 "prostate cancer: 5.9;renal cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 2.4;SK-BR-3: 4.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 13.3;cerebral cortex: 6.7;hippocampal formation: 7.4;medulla oblongata: 4.2" "Secreted to blood" NA NA 510000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.32e-1)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (2.73e-3)" "unprognostic (3.37e-1)" "unprognostic (1.15e-4)" "unprognostic (3.06e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (2.60e-1)" "prognostic favorable (4.44e-4)" "unprognostic (9.46e-2)" "prognostic favorable (1.29e-9)" "unprognostic (4.76e-3)" "unprognostic (1.91e-1)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" 3.3 1.4 0.9 0.8 3.1 0.1 2.5 0.8 1.5 1.8 47.1 2.1 2.7 1.2 8.8 1.1 0.8 1.3 1.1 4.2 1.1 128.7 0.4 3.5 1.0 0.5 0.5 0.1 1.2 135.2 0.3 30.4 0.5 8.0 0.9 0.0 0.8 2.5 0.7 0.6 2.6 1.2 0.6 2.4 2.0 0.5 0.8 0.5 1.3 1.5 0.5 1.6 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.1 0.8 1.5 4.2 1.1 0.5 0.5 0.5 0.6 0.8 0.5 15.8 0.0 0.5 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.6 0.3 1.0 0.0 0.7 12.9 0.0 0.2 0.0 0.4 5.9 0.0 1.8 0.1 2.5 10.2 16.3 0.4 1.2 0.0 0.1 1.6 0.0 0.1 0.0 0.1 1.1 0.2 2.8 0.0 0.5 1.1 0.0 0.9 1.0 0.8 0.3 1.9 0.0 6.5 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.6 1.8 123.3 0.7 0.0 0.0 1.1 2.3 1.4 0.5 0.0 0.1 0.1 1.1 0.1 1.9 0.1 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 NOTCH1 TAN1 ENSG00000148400 "Notch receptor 1" P46531 9 136494433-136546048 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Angiogenesis, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.2;Astrocytes: 67.3;Hepatic stellate cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 47.0;HDLM-2: 32.3;HMC-1: 39.7;MOLT-4: 72.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008112, CAB022466, HPA067168" Supported Approved Nucleoplasm NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "CAB008112: AB_2153490, CAB022466: , HPA067168: AB_2685795" "unprognostic (1.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.16e-1)" "unprognostic (8.38e-3)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (7.56e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-3)" "unprognostic (5.50e-3)" "unprognostic (8.78e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.14e-2)" "unprognostic (1.92e-1)" "unprognostic (5.65e-2)" "unprognostic (8.84e-2)" 18.2 4.2 10.4 4.9 16.1 4.3 15.0 12.1 9.3 14.3 0.0 19.8 4.3 12.7 0.2 16.3 11.9 0.9 14.9 8.6 5.5 11.8 9.2 22.2 3.0 13.5 12.3 5.1 14.0 0.7 6.3 2.6 9.8 15.4 0.6 0.6 10.7 3.1 5.0 24.2 14.2 1.3 9.7 24.8 10.0 2.5 13.9 4.0 11.2 1.2 0.9 14.2 16.5 14.0 8.8 10.6 4.0 2.6 0.0 0.4 17.7 3.3 0.4 1.4 0.4 1.8 0.9 13.3 10.3 1.3 1.6 47.0 1.0 8.6 0.1 32.3 2.0 5.5 6.1 0.6 2.1 6.9 39.7 0.3 16.7 1.4 1.9 0.7 9.0 3.7 3.6 1.1 0.0 9.0 72.3 13.1 8.4 2.9 7.7 15.7 9.2 19.3 0.6 4.2 0.0 0.7 6.1 4.3 3.4 1.0 3.2 10.4 22.7 5.0 9.3 5.9 4.3 2.4 2.6 4.1 3.7 5.0 26.1 0.2 0.4 0.6 0.3 0.1 0.1 0.1 0.1 0.5 0.3 0.0 0.1 0.3 2.3 0.7 0.1 0.1 0.1 0.5 10.4 16.1 12.1 9.3 8.6 5.5 13.5 12.3 9.8 9.7 13.9 14.0 56.2 9.6 21.9 67.3 8.4 24.9 12.3 35.1 23.9 0.8 10.7 12.4 11.0 5.7 16.3 1.8 2.1 1.1 14.2 11.8 0.0 5.1 0.3 12.3 9.9 53.2 2.4 5.2 0.3 4.0 2.2 6.4 1.1 17.3 34.9 1.0 68.2 7.7 9.3 1.7 0.4 14.8 18.3 10.1 17.5 0.3 1.2 15.2 7.2 18.7 14.3 46.6 24.7 33.7 19.6 2.1 11.5 0.7 5.7 8.4 4.1 3.4 3.8 2.0 6.6 14.7 18.4 0.2 3.3 20.6 29.8 1.1 15.0 1.4 28.8 15.6 NOTCH4 INT3 ENSG00000204301 "Notch receptor 4" Q99466 6 32194843-32224067 "Human disease related genes, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 24.2;breast: 19.8" "Group enriched" "Detected in many" 4 "Adipocytes: 263.8;Endothelial cells: 121.0;Hepatic stellate cells: 188.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA 6400000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (2.27e-1)" "unprognostic (2.27e-1)" "unprognostic (6.80e-3)" "unprognostic (9.50e-2)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (3.88e-2)" "unprognostic (3.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.93e-3)" "unprognostic (2.00e-1)" "prognostic unfavorable (3.84e-4)" "unprognostic (1.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" "unprognostic (3.13e-1)" 24.2 4.0 0.0 0.5 0.0 0.0 19.8 0.0 0.0 5.8 0.0 3.6 0.5 7.2 3.2 2.7 5.8 0.0 15.8 0.0 0.0 8.5 2.5 18.5 0.4 0.0 0.1 2.8 2.6 0.0 3.0 1.4 0.0 6.0 0.1 0.0 2.6 0.0 5.6 2.8 3.9 0.0 0.0 2.6 3.9 0.9 0.0 0.0 9.6 0.0 0.1 5.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 263.8 0.0 6.1 0.0 6.0 5.2 32.1 9.9 13.6 2.7 2.6 6.6 8.7 0.0 4.2 5.5 4.2 0.4 11.9 0.6 0.0 2.6 46.0 2.6 3.1 121.0 6.0 12.0 0.2 1.1 0.3 4.7 0.0 1.0 0.0 1.8 188.8 2.3 1.7 6.7 0.2 0.8 4.1 9.3 5.2 35.6 7.2 6.8 3.6 10.3 1.6 21.0 0.0 0.0 0.5 0.4 0.3 5.3 0.7 18.0 1.0 0.9 3.1 3.6 0.0 7.8 9.3 5.5 1.9 1.9 1.6 0.3 3.6 3.7 0.9 5.6 NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Human disease related genes, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7" "Cell type enhanced" "Detected in some" "Adipocytes: 39.4;Bipolar cells: 56.7;Endothelial cells: 32.0;Excitatory neurons: 21.8;Hepatic stellate cells: 42.5;Horizontal cells: 21.9;Inhibitory neurons: 20.9" "Cancer enriched" "Detected in many" 4 "glioma: 5.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.7;HDLM-2: 11.0;HUVEC TERT2: 16.9;SH-SY5Y: 5.6;TIME: 25.8;U-2 OS: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: AB_10962628" "unprognostic (9.84e-2)" "unprognostic (2.07e-1)" "unprognostic (9.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-1)" "unprognostic (3.04e-3)" "unprognostic (1.46e-1)" "unprognostic (6.21e-2)" "unprognostic (2.36e-1)" "unprognostic (3.02e-3)" "unprognostic (6.42e-5)" "unprognostic (1.16e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (5.05e-2)" "unprognostic (2.54e-1)" "unprognostic (1.41e-1)" "unprognostic (8.31e-2)" 6.7 1.9 12.4 0.7 15.1 0.0 5.7 0.5 16.7 3.2 0.0 1.8 0.6 3.4 0.6 1.4 2.9 1.4 6.7 16.0 5.8 4.7 1.0 9.3 0.5 4.6 3.0 1.2 1.1 1.0 6.2 3.9 3.6 2.3 0.5 5.6 1.1 0.8 2.3 1.1 1.7 2.0 0.6 1.5 1.5 2.0 4.6 0.4 4.5 2.5 0.2 2.5 2.0 9.8 0.0 0.1 9.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 1.3 0.0 0.0 11.0 0.4 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 5.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 15.1 0.5 16.7 16.0 5.8 4.6 3.0 3.6 0.6 4.6 9.8 39.4 0.0 0.0 5.9 0.1 0.6 0.2 0.0 0.6 56.7 0.1 0.5 3.4 1.5 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.1 32.0 0.0 0.0 21.8 0.2 0.0 1.2 0.0 0.1 0.0 0.1 42.5 0.5 0.1 21.9 20.9 0.0 0.0 1.6 1.5 3.5 0.0 0.1 0.0 9.4 0.0 1.3 0.0 11.6 9.5 0.2 0.0 0.4 1.2 0.3 0.0 0.0 0.0 3.3 0.0 0.6 0.6 2.4 2.3 0.3 0.1 0.0 0.5 0.4 0.0 0.3 PEA15 "HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15" ENSG00000162734 "Proliferation and apoptosis adaptor protein 15" Q15121 1 160205380-160215376 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 246.3;monocytes: 267.6;Muller glia cells: 315.8" "Cancer enhanced" "Detected in all" "glioma: 466.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 78.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028356, HPA070820" Enhanced Supported Nucleoplasm,Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Cytosol Nucleoplasm "HPA028356: AB_10602814, HPA070820: AB_2732166" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (1.64e-2)" "unprognostic (1.99e-3)" "unprognostic (6.10e-2)" "unprognostic (4.57e-1)" "unprognostic (1.25e-1)" "unprognostic (6.31e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (6.53e-7)" "unprognostic (2.60e-2)" "unprognostic (1.39e-1)" "unprognostic (2.82e-3)" "unprognostic (1.24e-1)" 190.2 82.2 863.3 121.7 900.6 16.6 142.7 908.1 949.4 110.1 612.5 146.5 31.7 124.5 83.4 119.2 104.2 88.2 241.9 884.6 939.2 112.0 41.2 147.9 75.5 1028.2 1010.2 80.4 39.6 85.4 80.0 102.3 981.5 112.2 58.5 461.4 80.8 119.4 61.1 105.6 64.8 194.6 933.0 103.2 75.8 80.5 915.2 40.7 83.5 84.5 96.9 133.4 110.2 1106.4 139.2 46.8 190.5 82.5 344.5 191.5 63.6 593.2 503.3 471.6 328.5 103.7 72.3 63.4 210.9 729.4 226.6 146.4 71.5 181.7 365.3 34.4 40.2 52.4 32.5 26.7 423.9 17.8 62.0 161.8 100.7 260.2 328.5 259.6 360.7 45.7 55.1 111.8 640.6 68.3 21.0 41.1 127.0 160.9 134.3 34.4 200.6 43.8 173.0 71.0 38.0 100.0 310.4 207.6 179.9 409.4 128.1 122.6 487.7 311.3 246.4 234.4 254.5 88.1 59.5 118.7 287.1 33.2 450.8 1.3 39.3 5.2 8.4 78.2 6.5 18.9 6.2 6.9 56.7 13.5 3.8 4.2 1.8 7.9 38.7 25.0 7.9 14.9 863.3 900.6 908.1 949.4 884.6 939.2 1028.2 1010.2 981.5 933.0 915.2 1106.4 137.8 16.0 29.9 40.5 38.6 80.2 124.2 21.8 33.6 172.1 76.9 60.2 246.3 11.5 24.7 5.5 73.0 21.8 13.7 12.7 29.4 74.7 65.4 36.4 33.7 125.1 12.0 7.4 24.8 46.3 61.1 81.5 17.9 85.9 31.1 17.2 89.3 6.5 63.3 92.5 19.1 12.0 8.2 42.6 234.6 55.4 66.8 68.9 74.7 14.0 267.6 315.8 8.2 12.1 48.3 102.5 4.7 109.9 14.8 119.4 5.4 18.3 13.8 129.2 46.0 69.4 78.3 16.5 4.1 42.7 73.3 45.3 19.4 18.5 12.8 178.8 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 335.7" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 378.4" "Group enriched" "Detected in all" 4 "granulocytes: 378.4;monocytes: 176.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 440000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026010: , HPA065232: AB_2685440" "unprognostic (5.16e-2)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-2)" "unprognostic (3.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.77e-2)" "unprognostic (4.15e-2)" "unprognostic (4.91e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (2.29e-2)" "unprognostic (8.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" 53.8 35.9 30.6 57.2 30.8 60.0 39.9 32.8 38.7 44.3 33.1 59.2 50.5 37.5 15.8 73.3 45.7 44.8 51.0 32.3 37.7 56.5 34.2 50.7 35.8 30.8 33.6 28.7 25.6 335.7 16.6 63.1 30.6 51.0 51.8 25.8 36.2 31.7 30.1 25.7 44.8 46.5 31.3 54.2 39.3 29.9 37.9 27.5 30.8 43.9 35.0 51.0 49.1 32.8 179.8 47.7 46.8 29.5 71.2 115.5 66.7 121.4 105.8 93.3 70.5 99.4 118.0 7.1 63.9 131.6 88.2 64.1 22.5 93.1 85.7 293.3 25.8 84.4 36.3 71.3 46.0 45.1 144.9 60.3 99.0 97.2 74.0 77.1 272.9 6.3 66.5 28.1 108.2 91.9 5.9 100.0 31.7 71.6 101.9 1.2 59.3 38.1 97.5 45.6 13.3 32.1 50.4 137.9 85.1 39.3 43.3 66.3 168.4 91.1 69.8 93.9 48.8 16.2 9.1 12.8 72.7 57.5 95.6 101.8 80.9 230.5 19.0 117.7 18.5 45.0 18.0 19.0 65.4 59.6 11.9 13.7 378.4 25.5 176.1 6.9 24.6 59.5 30.6 30.8 32.8 38.7 32.3 37.7 30.8 33.6 30.6 31.3 37.9 32.8 69.3 9.6 27.0 6.5 23.8 19.4 30.1 22.4 7.4 4.1 23.2 7.9 55.8 18.6 21.9 11.0 12.5 6.0 11.8 95.3 66.5 84.9 18.8 28.4 22.8 77.8 18.6 8.4 12.9 55.0 128.5 32.7 17.9 26.7 106.1 90.6 78.5 9.8 53.6 13.5 9.7 19.1 18.3 54.3 59.4 23.0 19.9 66.7 35.6 16.9 62.6 26.3 21.6 10.1 5.4 138.1 62.1 31.2 6.7 28.5 44.6 104.4 46.3 7.5 19.7 18.3 33.4 13.1 16.2 16.4 18.9 36.7 19.5 12.9 31.3 32.2 RASIP1 "FLJ20401, RAIN" ENSG00000105538 "Ras interacting protein 1" Q5U651 19 48720585-48740610 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 121.8;Endothelial cells: 83.9;Hepatic stellate cells: 94.2;Theca cells: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 14.7;HeLa: 13.9;HUVEC TERT2: 38.5;SiHa: 21.1;TIME: 52.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077251 Approved NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA077251: AB_2732337" "unprognostic (9.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (3.64e-2)" "prognostic favorable (7.17e-5)" "unprognostic (8.44e-2)" "unprognostic (2.63e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "prognostic favorable (9.46e-4)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (1.32e-1)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" 24.4 7.0 5.9 2.6 4.3 0.7 21.0 4.4 4.6 9.2 1.4 5.6 2.5 11.2 1.1 5.1 9.9 3.8 18.8 3.6 4.0 12.6 2.6 27.9 2.2 4.9 5.3 4.9 13.2 1.6 4.1 7.9 5.9 5.5 0.7 0.1 4.8 2.7 7.7 6.0 5.7 4.2 4.5 16.8 10.3 6.8 7.3 1.5 10.5 4.0 1.4 7.6 7.7 3.6 10.2 0.1 0.2 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.6 1.1 0.8 2.2 0.0 0.0 2.5 0.2 2.2 0.0 0.0 14.7 0.2 13.9 0.4 2.2 0.0 0.7 2.2 1.2 0.0 0.0 0.0 38.5 1.3 1.3 0.1 0.0 0.9 0.0 1.3 0.3 0.4 0.0 0.2 0.0 0.4 0.0 0.8 6.7 0.5 21.1 0.0 0.0 0.1 0.1 0.0 52.4 0.0 0.4 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 4.3 4.4 4.6 3.6 4.0 4.9 5.3 5.9 4.5 7.3 3.6 121.8 0.0 1.3 0.0 1.2 6.5 5.7 2.0 0.6 1.1 5.9 10.8 7.3 1.5 1.2 1.8 0.0 0.4 0.7 0.1 0.0 0.7 5.9 3.2 4.8 83.9 0.0 2.7 3.4 0.7 1.9 9.5 2.0 3.8 0.0 6.0 94.2 1.9 0.7 6.7 1.1 0.1 4.1 6.3 3.0 5.2 10.2 1.0 19.6 16.9 0.0 2.1 0.0 1.5 1.5 0.8 0.0 11.3 1.4 10.1 0.2 0.3 2.1 0.7 19.7 1.9 6.2 1.0 11.0 3.7 6.0 0.3 1.0 40.2 0.2 6.4 RIPOR1 "FAM65A, FLJ13725" ENSG00000039523 "RHO family interacting cell polarization regulator 1" Q6ZS17 16 67518418-67546788 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Endothelial cells: 23.6;Hofbauer cells: 30.0;Pancreatic endocrine cells: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 11.2;eosinophil: 9.3;intermediate monocyte: 15.6;memory B-cell: 15.8;myeloid DC: 10.2;naive B-cell: 9.4;neutrophil: 6.6;non-classical monocyte: 15.1;plasmacytoid DC: 14.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005923 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Cytosol" "HPA005923: AB_1078809" "unprognostic (7.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.56e-3)" "unprognostic (3.71e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.10e-2)" "prognostic unfavorable (5.00e-5)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (3.38e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.82e-8)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (1.19e-1)" "unprognostic (7.46e-2)" 44.4 28.1 27.6 23.4 30.6 27.2 37.7 26.4 38.6 39.9 7.5 36.0 8.8 45.2 6.0 18.5 36.2 21.5 53.6 33.6 16.3 67.6 16.7 55.8 20.8 26.6 17.1 33.2 30.1 20.6 26.5 29.8 25.4 30.6 7.4 43.8 22.8 20.2 34.9 21.4 32.7 25.2 12.3 61.2 25.9 18.6 21.5 10.8 36.4 22.3 17.5 37.1 30.4 18.6 44.0 36.6 16.1 25.3 40.0 35.7 35.7 45.7 44.9 51.6 43.0 75.7 31.5 6.0 62.4 78.8 26.0 24.4 32.7 41.3 33.2 19.3 17.0 57.9 53.6 17.4 44.7 4.6 28.0 35.5 18.8 69.7 47.1 36.8 55.2 10.2 6.5 6.4 38.7 47.7 13.8 14.4 4.4 8.5 29.1 46.8 29.0 31.2 39.0 22.1 12.1 31.9 85.1 13.8 28.6 15.9 30.2 10.7 96.8 58.3 34.2 49.8 32.2 9.0 6.8 17.8 38.8 11.1 31.7 0.1 11.2 9.3 1.2 15.6 1.8 15.8 1.0 0.5 10.2 9.4 0.7 0.7 6.6 1.7 15.1 14.4 0.8 6.0 27.6 30.6 26.4 38.6 33.6 16.3 26.6 17.1 25.4 12.3 21.5 18.6 49.2 16.0 16.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 12.1 8.8 0.0 0.0 1.8 7.3 0.0 0.8 3.7 0.0 0.0 15.8 0.0 9.3 17.9 23.6 0.0 0.0 0.0 12.5 1.3 6.9 0.0 18.5 10.1 7.9 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 37.0 0.0 0.0 2.3 0.0 0.0 5.8 2.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 2.1 2.3 16.6 0.0 0.0 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 60.1;brain: 75.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.9;Hepatic stellate cells: 145.6;Horizontal cells: 138.0;Oligodendrocyte precursor cells: 138.7;Oligodendrocytes: 311.3;Syncytiotrophoblasts: 348.1" "Cancer enhanced" "Detected in all" "testis cancer: 20.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 44.3;HAP1: 52.0;NTERA-2: 115.2;SuSa: 221.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 620000 "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: AB_10610423, HPA031267: " "unprognostic (3.79e-2)" "unprognostic (3.91e-1)" "unprognostic (1.82e-2)" "unprognostic (6.81e-2)" "unprognostic (2.69e-2)" "unprognostic (3.77e-1)" "prognostic unfavorable (4.39e-4)" "unprognostic (1.64e-1)" "unprognostic (4.71e-2)" "unprognostic (5.82e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.62e-3)" "unprognostic (1.92e-1)" "unprognostic (6.21e-3)" "unprognostic (7.32e-3)" 13.4 60.1 24.1 4.9 48.6 3.5 13.1 39.9 31.9 10.0 0.3 20.6 19.9 6.0 2.8 4.4 8.2 12.9 7.1 24.5 40.3 8.6 5.6 17.9 4.5 51.9 41.0 18.1 11.2 2.0 5.8 31.9 50.0 6.0 17.5 10.4 16.6 2.5 8.2 6.9 25.5 5.8 32.9 11.2 7.0 7.5 44.1 3.6 9.1 6.5 2.2 5.6 8.1 75.2 0.3 0.1 36.9 44.3 0.2 0.0 38.2 0.7 0.4 0.2 0.2 2.2 1.5 1.6 1.7 0.6 0.7 0.4 52.0 0.0 0.1 1.6 7.7 0.7 0.7 13.1 0.5 0.5 2.6 0.7 0.0 0.0 0.0 0.5 0.2 0.3 0.3 0.4 0.2 0.8 0.7 3.9 115.2 0.2 0.3 6.9 24.2 1.8 19.0 33.7 10.3 3.7 0.2 0.7 19.7 221.1 14.4 2.6 0.9 3.6 3.1 0.4 1.5 0.6 0.7 0.8 0.6 1.8 13.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 24.1 48.6 39.9 31.9 24.5 40.3 51.9 41.0 50.0 32.9 44.1 75.2 64.7 0.0 0.6 71.8 1.1 6.5 0.7 13.1 34.7 17.9 17.0 8.3 8.6 61.5 3.1 14.7 2.1 128.9 0.3 73.3 0.0 42.9 13.6 12.2 4.8 60.9 28.1 2.7 26.9 1.3 8.1 15.4 1.1 10.6 0.0 9.7 145.6 0.9 12.5 138.0 62.2 30.7 0.0 14.8 4.6 2.4 6.5 1.1 24.9 54.4 0.1 5.8 0.0 138.7 311.3 2.0 46.7 1.9 2.6 1.5 40.7 4.4 0.6 3.5 0.0 36.1 8.1 0.9 1.5 11.3 4.1 348.1 0.8 3.5 40.3 2.2 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TIE1 "JTK14, TIE" ENSG00000066056 "Tyrosine kinase with immunoglobulin like and EGF like domains 1" P35590 1 43300982-43323108 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 130.8;Endothelial cells: 108.8;Hepatic stellate cells: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 2.1;NK-cell: 2.5" "Group enriched" "Detected in many" 24 "granulocytes: 2.1;NK-cells: 2.5" "Group enriched" "Detected in some" 4 "EFO-21: 106.3;HUVEC TERT2: 238.4;TIME: 210.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA 87000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "unprognostic (1.53e-3)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.02e-1)" "unprognostic (9.34e-2)" "unprognostic (1.91e-2)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (2.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.29e-2)" "unprognostic (2.35e-2)" 47.0 10.1 16.6 8.1 14.8 0.9 37.8 14.6 16.9 14.0 10.1 11.2 5.2 20.4 5.3 6.5 16.0 13.3 34.2 13.1 14.2 19.8 6.7 35.3 10.1 16.4 16.5 7.5 4.2 3.2 8.0 48.6 16.8 10.8 3.1 0.4 7.4 6.5 14.0 7.9 11.0 14.1 13.9 19.9 8.8 3.0 21.1 2.1 24.2 20.7 2.9 15.1 11.8 14.8 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 106.3 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 41.9 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.7 238.4 0.0 0.0 0.0 0.0 0.0 0.0 20.4 1.3 0.0 0.1 8.1 16.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.1 210.0 1.2 0.4 0.0 0.2 0.0 0.2 0.4 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 16.6 14.8 14.6 16.9 13.1 14.2 16.4 16.5 16.8 13.9 21.1 14.8 130.8 0.0 4.2 0.0 0.4 2.2 0.6 0.0 1.2 0.3 1.0 0.9 4.9 1.5 1.8 0.0 0.0 0.3 0.7 0.9 0.0 0.0 2.0 0.1 0.4 108.8 0.0 2.5 0.4 0.2 0.1 3.1 0.0 0.4 20.3 0.1 128.8 1.3 0.5 0.0 0.2 0.1 0.0 5.6 3.1 2.5 2.1 1.1 1.8 29.0 0.1 0.1 1.0 1.0 1.1 0.0 0.0 0.7 0.1 0.7 0.1 0.9 3.6 0.9 0.0 2.2 2.2 0.9 0.7 0.5 1.4 0.3 2.3 0.5 0.2 0.7 USHBP1 "AIEBP, FLJ38709, MCC2" ENSG00000130307 "USH1 protein network component harmonin binding protein 1" Q8N6Y0 19 17249171-17282786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 41.5;Endothelial cells: 28.3;Hepatic stellate cells: 21.4;Ionocytes: 20.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 10.9;HeLa: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA052471 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA052471: AB_2681843" "unprognostic (1.48e-1)" "unprognostic (1.82e-1)" "unprognostic (2.91e-2)" "unprognostic (3.97e-2)" "unprognostic (1.73e-2)" "unprognostic (2.66e-3)" "unprognostic (1.44e-3)" "unprognostic (3.94e-2)" "unprognostic (4.42e-3)" "unprognostic (2.52e-1)" "unprognostic (4.46e-3)" "unprognostic (5.12e-1)" "unprognostic (5.12e-2)" "unprognostic (1.16e-1)" "unprognostic (6.88e-2)" "unprognostic (8.45e-2)" "unprognostic (1.88e-1)" 8.8 1.9 5.0 1.6 4.9 2.9 8.2 7.2 5.2 2.9 4.1 1.9 1.9 3.6 1.1 1.3 3.1 1.7 12.6 5.0 4.1 4.5 1.2 6.9 2.6 4.6 4.5 1.4 4.8 0.8 1.2 5.6 5.1 2.3 0.5 1.1 2.0 0.9 6.2 2.1 2.2 1.3 3.3 3.5 1.7 1.0 5.1 0.5 4.5 4.8 0.5 2.8 2.3 4.6 0.6 0.9 1.7 0.4 0.0 0.0 10.9 0.3 0.0 0.0 0.0 1.9 0.9 2.9 3.4 0.0 0.1 1.2 0.1 0.2 0.0 0.7 1.3 0.7 5.0 1.1 0.0 2.4 2.4 0.3 0.0 0.2 0.2 0.6 3.2 1.1 1.4 1.5 0.0 0.1 0.4 2.4 1.3 0.3 2.7 1.4 0.2 0.7 0.0 1.3 1.1 0.7 0.7 0.7 0.2 0.9 1.3 0.9 1.9 1.8 0.5 1.5 1.0 2.6 0.9 2.8 0.6 1.5 0.6 2.0 0.4 0.7 0.7 0.3 0.6 0.6 0.6 0.7 0.1 1.0 0.9 0.8 1.6 0.7 0.2 0.8 0.8 0.5 5.0 4.9 7.2 5.2 5.0 4.1 4.6 4.5 5.1 3.3 5.1 4.6 41.5 3.2 0.5 0.7 0.0 0.5 0.9 0.1 0.6 0.3 0.5 0.1 6.7 0.0 0.7 0.0 0.0 1.1 3.1 0.2 0.0 0.1 0.7 0.7 0.8 28.3 0.0 0.0 0.4 0.6 0.9 0.9 0.0 1.5 1.3 0.1 21.4 0.3 0.1 0.0 0.5 0.2 20.3 0.6 1.2 0.2 0.6 0.3 5.4 6.5 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 1.3 0.1 1.7 0.0 2.2 1.5 0.2 0.4 0.2 1.0 4.5 0.7 0.3 0.0 0.8 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0