Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" TUBB8B TUBB8P12 ENSG00000173213 "Tubulin beta 8B" A6NNZ2 18 47390-49557 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 2.1" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.29e-1)" "unprognostic (6.73e-2)" "unprognostic (1.76e-1)" "unprognostic (6.91e-2)" "unprognostic (1.92e-1)" "unprognostic (4.36e-2)" "unprognostic (1.29e-1)" "unprognostic (2.09e-1)" "unprognostic (4.46e-2)" "unprognostic (7.42e-4)" "unprognostic (3.96e-2)" "unprognostic (5.98e-2)" "unprognostic (4.88e-2)" "unprognostic (3.21e-2)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 THOC1 "HPR1, P84" ENSG00000079134 "THO complex 1" Q96FV9 18 214520-268050 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019096, HPA019687" Enhanced Enhanced "Nuclear speckles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA019096: AB_1857979, HPA019687: AB_1857980" "prognostic favorable (8.43e-4)" "unprognostic (2.06e-3)" "unprognostic (1.84e-1)" "unprognostic (3.69e-2)" "unprognostic (8.75e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.83e-5)" "unprognostic (6.74e-3)" "unprognostic (2.49e-3)" "prognostic favorable (2.89e-5)" "unprognostic (3.60e-2)" "unprognostic (1.35e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (2.03e-1)" "unprognostic (2.24e-1)" "unprognostic (3.42e-1)" "prognostic favorable (9.62e-4)" 6.0 5.2 8.7 8.1 9.7 7.5 5.8 10.0 12.2 5.5 9.8 6.6 6.3 4.7 4.5 6.5 4.1 4.6 4.6 8.8 8.8 7.5 9.9 4.6 12.3 9.4 9.0 4.7 3.9 6.7 3.7 6.4 9.9 5.1 5.5 5.8 6.9 4.1 6.2 6.3 5.9 5.7 8.8 6.3 5.3 16.8 9.5 12.8 4.7 6.2 11.6 9.5 3.8 10.7 27.0 15.8 32.4 26.1 20.8 15.4 40.2 15.4 14.5 29.8 31.1 30.8 16.1 37.2 11.9 20.0 46.0 17.1 43.0 24.4 36.9 12.3 19.1 22.2 18.4 21.0 16.0 50.5 20.2 10.6 14.4 33.3 21.8 13.6 33.3 34.5 52.3 17.4 27.3 20.5 38.1 29.6 31.5 34.2 21.1 53.3 30.3 33.4 17.2 26.1 21.2 16.6 39.0 19.9 25.3 36.7 14.0 37.1 16.6 26.6 29.9 21.8 48.3 15.9 26.4 54.7 22.2 36.0 22.8 13.4 7.3 6.4 9.8 10.7 14.8 13.3 11.7 12.4 11.9 11.5 13.5 13.4 0.7 11.2 9.4 7.2 12.8 6.6 8.7 9.7 10.0 12.2 8.8 8.8 9.4 9.0 9.9 8.8 9.5 10.7 20.4 19.2 11.7 48.3 21.0 12.9 15.6 16.8 23.9 30.8 13.1 14.1 9.6 2.8 17.9 11.0 20.9 24.7 23.2 6.0 15.6 16.5 67.1 15.0 23.6 16.7 9.5 21.0 45.3 8.2 16.7 19.9 9.2 21.9 27.3 32.4 8.2 10.3 16.1 28.6 51.6 8.7 10.2 6.9 11.1 11.6 19.3 15.0 3.6 32.8 14.3 12.9 10.3 41.7 74.6 12.7 7.0 17.0 15.6 16.7 9.2 10.2 10.5 27.6 6.6 21.6 22.9 73.4 30.5 13.8 9.1 18.7 22.3 17.7 13.4 12.9 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 CETN1 "CEN1, CETN" ENSG00000177143 "Centrin 1" Q12798 18 580380-582114 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1084 "testis: 134.3" "Group enriched" "Detected in some" 34 "Early spermatids: 930.9;Late spermatids: 435.6;Spermatocytes: 675.9" "Cancer enriched" "Detected in single" 10 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001470, HPA028956, CAB037244, HPA069157" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centriolar satellite, Cytosol" "CAB037244: AB_476871, HPA001470: , HPA028956: AB_10601798, HPA069157: " "unprognostic (1.51e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 930.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 435.6 12.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 675.9 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 TYMS "HsT422, TMS, TS, Tsase" ENSG00000176890 "Thymidylate synthetase" P04818 18 657653-673578 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Methyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.5;lymphoid tissue: 113.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 105.8;Erythroid cells: 189.3;Extravillous trophoblasts: 115.3;Plasma cells: 112.7;Spermatocytes: 180.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 14.1" "Group enriched" "Detected in many" 6 "NK-cells: 6.7;T-cells: 14.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB002784, HPA074922" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB002784: , HPA074922: " "unprognostic (7.58e-2)" "unprognostic (2.06e-3)" "unprognostic (9.31e-2)" "unprognostic (2.34e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (5.10e-6)" "unprognostic (1.62e-3)" "unprognostic (1.68e-2)" "unprognostic (9.82e-2)" "unprognostic (1.07e-3)" "unprognostic (3.28e-2)" "unprognostic (1.23e-2)" "unprognostic (6.34e-2)" "unprognostic (1.66e-1)" "unprognostic (5.65e-3)" "unprognostic (2.47e-1)" 4.5 3.1 4.3 24.2 7.5 88.5 6.7 4.1 6.5 4.8 2.7 22.9 10.5 5.1 1.3 14.8 5.6 3.8 2.2 5.0 4.9 6.5 11.8 4.9 36.1 4.9 5.2 2.1 3.6 1.8 1.6 22.3 4.4 3.1 27.1 4.2 3.9 2.0 0.4 6.2 14.8 12.7 4.8 10.6 8.8 34.3 6.1 113.6 2.1 0.4 44.5 8.4 5.5 10.3 102.7 156.6 320.4 154.9 35.1 57.9 159.9 238.9 141.1 251.7 299.9 132.8 80.1 160.0 91.5 129.9 143.2 45.1 225.3 89.7 216.1 152.3 244.9 273.1 135.8 229.4 8.2 564.8 286.5 51.5 20.7 159.6 49.6 48.4 214.4 334.0 222.0 249.6 321.8 118.1 687.7 311.4 114.7 124.3 114.0 446.8 287.0 191.3 95.6 88.9 106.0 175.7 201.4 91.6 61.1 197.3 63.5 253.5 85.0 289.7 569.5 267.3 474.2 305.9 405.2 367.3 75.2 240.6 339.2 0.0 0.0 1.3 1.1 0.1 0.0 1.1 2.8 2.2 1.8 0.0 0.0 0.6 0.7 6.7 0.1 0.3 14.1 2.9 4.3 7.5 4.1 6.5 5.0 4.9 4.9 5.2 4.4 4.8 6.1 10.3 2.1 0.0 2.3 1.6 15.7 14.4 15.9 13.0 27.9 0.5 7.8 11.7 3.6 2.8 6.7 0.0 0.0 105.8 14.5 15.5 1.9 2.3 34.4 5.6 8.4 12.5 1.2 189.3 0.4 0.8 115.3 28.3 14.3 7.4 7.0 76.2 6.8 4.3 71.4 0.0 0.6 20.9 10.2 15.6 19.4 31.9 6.2 10.7 10.6 1.0 3.9 45.0 5.2 0.5 15.6 1.5 8.9 3.8 112.7 5.0 13.8 36.6 1.0 2.4 13.1 1.3 32.6 180.8 30.7 48.0 7.2 27.0 21.3 10.5 54.9 18.7 ENOSF1 "FUCD, HSRTSBETA, rTS, TYMSAS" ENSG00000132199 "Enolase superfamily member 1" Q7L5Y1 18 670318-712662 "Enzymes, Predicted intracellular proteins" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 216.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA047829 Enhanced NA NA 7300 "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA047829: AB_2680170" "prognostic favorable (2.27e-4)" "unprognostic (8.03e-2)" "unprognostic (2.02e-2)" "unprognostic (7.87e-3)" "unprognostic (1.85e-1)" "unprognostic (4.29e-2)" "unprognostic (6.48e-3)" "unprognostic (1.55e-2)" "unprognostic (3.50e-3)" "unprognostic (1.33e-3)" "unprognostic (2.44e-2)" "unprognostic (5.07e-3)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.36e-1)" "unprognostic (5.03e-2)" "unprognostic (1.31e-2)" 8.4 25.0 3.1 3.2 4.4 7.7 9.3 3.3 7.2 10.0 5.5 12.0 5.5 6.6 2.1 12.0 10.6 3.2 11.0 2.9 4.2 28.0 29.3 8.1 2.8 3.8 3.4 8.6 15.8 5.0 11.3 4.0 3.7 13.3 3.9 5.9 14.9 2.5 5.0 7.5 11.0 2.3 3.2 9.5 14.6 5.3 4.0 3.2 18.6 1.6 1.9 9.0 8.1 5.3 3.5 9.6 6.0 5.8 1.6 2.1 5.2 4.9 5.4 1.0 3.6 10.6 10.5 3.8 1.8 0.8 4.1 4.1 8.0 3.7 2.2 2.6 4.4 7.2 12.0 5.4 6.9 11.8 3.2 3.2 8.5 1.7 5.7 1.7 5.7 10.5 6.2 9.6 2.0 8.8 13.8 7.3 2.6 13.1 5.0 4.7 2.2 12.7 5.3 14.0 7.6 3.1 7.7 8.4 2.7 2.2 3.2 14.2 2.9 2.8 5.4 5.5 2.6 14.0 15.2 8.1 12.8 8.3 2.6 0.0 0.5 1.4 3.5 1.6 2.7 0.8 2.3 1.9 0.8 0.5 3.3 3.4 0.1 1.2 0.6 2.4 1.7 0.9 3.1 4.4 3.3 7.2 2.9 4.2 3.8 3.4 3.7 3.2 4.0 5.3 17.9 35.3 99.5 36.9 10.1 11.9 29.5 29.6 24.5 35.2 38.4 36.4 19.6 28.6 44.7 47.8 116.7 44.6 25.6 36.7 115.4 32.4 7.0 61.6 32.2 19.6 24.7 73.2 4.2 14.4 27.7 26.5 61.2 40.1 22.2 26.2 23.9 56.6 39.1 0.0 7.6 36.0 38.7 12.6 8.8 6.8 23.6 20.9 19.6 30.0 12.1 30.9 24.7 38.2 143.6 21.9 36.2 28.2 25.2 25.9 50.9 216.9 78.3 98.8 13.1 38.7 15.8 14.7 29.3 39.8 12.1 37.8 22.0 67.8 49.4 20.8 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 ADCYAP1 PACAP ENSG00000141433 "Adenylate cyclase activating polypeptide 1" P18509 18 904871-912172 "Predicted secreted proteins" Neurogenesis Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.9;lymphoid tissue: 10.9" "Group enriched" "Detected in some" 6 "Excitatory neurons: 13.4;granulocytes: 43.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SCLC-21H: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065887 Supported Supported "Secreted in other tissues" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA065887: " "unprognostic (2.68e-1)" "unprognostic (1.83e-2)" "unprognostic (7.09e-2)" "unprognostic (4.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.87e-4)" "unprognostic (9.58e-3)" "unprognostic (1.00e-1)" "unprognostic (2.34e-1)" "unprognostic (6.86e-2)" "unprognostic (4.16e-2)" "unprognostic (9.94e-2)" "prognostic favorable (2.91e-6)" "unprognostic (2.24e-3)" "unprognostic (9.22e-2)" "unprognostic (1.74e-1)" "unprognostic (5.74e-4)" 1.8 0.2 1.9 10.9 2.6 0.0 1.3 0.3 2.9 2.1 0.0 1.8 0.1 3.0 0.0 1.3 0.4 7.1 0.5 2.7 21.7 0.5 0.2 1.6 1.0 31.9 6.8 0.1 4.8 0.2 3.5 0.1 13.7 1.4 1.1 0.3 1.9 0.5 0.2 0.7 1.3 1.0 5.4 0.1 1.5 2.5 17.7 0.4 0.2 0.0 1.0 2.3 1.3 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.6 0.3 2.9 2.7 21.7 31.9 6.8 13.7 5.4 17.7 2.0 0.2 3.2 0.6 0.3 0.0 0.6 0.1 0.1 0.0 0.5 0.1 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 13.4 0.0 0.0 2.4 0.0 0.0 43.1 0.0 0.4 0.0 0.1 0.0 0.5 0.0 4.1 0.0 0.9 1.5 0.3 0.2 0.0 1.9 0.0 0.2 0.0 0.5 1.1 2.0 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 2.6 0.0 0.0 0.4 0.0 2.0 0.0 0.0 0.2 METTL4 "FLJ23017, HsT661" ENSG00000101574 "Methyltransferase like 4" Q8N3J2 18 2537525-2571509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040061, HPA046734" Approved Approved Mitochondria NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA040061: AB_10697713, HPA046734: AB_2732532" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (7.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (5.06e-3)" "unprognostic (1.12e-5)" "unprognostic (1.74e-1)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.89e-1)" "unprognostic (7.72e-2)" "unprognostic (3.26e-1)" "unprognostic (4.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.05e-3)" 7.4 4.9 5.2 7.9 6.0 5.5 5.8 5.7 7.0 8.4 5.6 5.9 5.7 7.5 5.4 6.1 6.2 5.7 5.6 4.9 5.7 6.4 5.0 6.2 11.5 6.3 5.6 6.8 4.4 6.4 5.2 5.9 6.5 6.6 6.7 5.1 5.5 7.1 3.4 5.9 7.9 6.7 6.1 10.4 5.8 7.3 5.6 10.4 8.9 5.5 11.0 6.8 7.8 7.6 12.7 5.0 15.1 8.3 5.9 8.7 19.0 19.9 15.7 18.2 16.9 10.8 9.2 24.3 11.5 8.3 16.4 10.7 24.7 9.3 21.2 18.6 9.1 10.6 10.5 7.9 9.0 23.1 12.0 7.1 19.3 19.6 12.0 10.3 17.8 15.9 14.0 33.8 14.3 5.7 16.0 7.4 9.2 10.5 8.2 12.5 13.6 16.7 8.9 7.0 27.6 12.8 16.2 9.3 18.6 11.6 10.8 14.8 11.1 21.9 28.9 19.4 26.3 16.1 47.6 15.7 14.1 15.5 23.8 18.6 2.7 7.3 6.1 2.6 7.0 6.2 7.0 8.5 1.9 7.3 8.5 7.9 10.0 5.9 2.2 3.8 8.8 4.9 5.2 6.0 5.7 7.0 4.9 5.7 6.3 5.6 6.5 6.1 5.6 7.6 24.3 12.8 8.2 8.5 21.1 4.8 13.6 6.5 10.8 9.6 7.6 7.4 3.8 10.0 10.3 3.7 14.6 7.5 13.7 10.1 0.0 5.9 6.9 7.5 9.1 10.0 2.4 11.0 17.0 7.3 9.4 7.3 12.2 7.4 7.0 10.3 11.4 4.9 6.0 8.4 20.3 7.6 4.1 7.0 6.5 3.3 12.8 7.0 3.6 14.0 4.5 6.6 13.4 18.1 25.8 8.3 4.0 10.9 15.0 10.8 10.1 5.1 12.0 6.5 13.1 8.3 6.8 30.5 21.8 9.0 4.8 10.4 18.3 8.5 6.2 19.4 NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 63.4;Spermatocytes: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.2;granulocytes: 8.3;T-cells: 11.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA066330 Supported Nucleoplasm,Centrosome NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA066330: AB_2685661" "unprognostic (1.96e-1)" "unprognostic (5.38e-2)" "unprognostic (2.96e-1)" "unprognostic (2.21e-3)" "unprognostic (1.87e-1)" "unprognostic (3.63e-2)" "prognostic unfavorable (2.53e-8)" "unprognostic (1.16e-2)" "unprognostic (2.58e-3)" "unprognostic (2.86e-2)" "unprognostic (3.19e-3)" "unprognostic (7.74e-2)" "unprognostic (0.00e+0)" "unprognostic (9.69e-3)" "unprognostic (1.69e-1)" "unprognostic (3.50e-2)" "unprognostic (1.71e-1)" 1.8 0.9 1.4 9.6 1.3 31.2 2.5 2.2 1.7 2.7 0.1 7.0 5.9 4.3 2.1 5.6 1.2 2.5 1.2 1.0 0.6 1.2 1.6 1.5 20.5 1.9 0.6 0.8 0.9 0.5 0.1 10.4 2.9 5.3 9.8 0.7 1.1 14.0 0.9 7.9 6.2 5.0 0.4 5.5 3.8 15.1 1.2 29.2 1.6 0.6 19.3 3.2 4.6 2.5 80.3 17.7 86.5 38.6 4.5 9.8 44.5 91.7 49.1 117.7 99.7 49.2 44.0 86.6 40.4 35.9 49.7 47.9 98.2 39.9 123.6 32.2 24.6 68.8 49.5 38.1 1.5 133.2 55.1 5.1 3.7 67.8 47.8 12.0 54.3 52.8 56.8 107.1 104.0 36.2 65.1 57.2 44.9 51.6 25.3 71.0 88.6 69.7 31.0 38.0 69.3 31.4 84.4 21.7 32.7 34.0 36.7 52.4 33.2 75.7 168.1 60.7 123.2 46.5 78.6 116.0 33.5 60.8 65.8 3.5 0.6 2.5 1.8 0.4 1.7 7.2 3.2 3.8 0.2 5.3 2.0 2.0 8.3 1.7 0.5 1.3 11.3 1.3 1.4 1.3 2.2 1.7 1.0 0.6 1.9 0.6 2.9 0.4 1.2 2.5 2.8 0.0 0.6 0.3 5.8 2.3 0.7 3.8 0.6 0.0 0.6 0.9 15.8 0.0 2.4 0.0 0.0 15.5 4.8 2.1 0.0 0.9 22.0 1.3 3.7 1.9 0.0 63.4 0.6 0.4 21.7 6.8 2.6 2.1 0.0 20.8 5.7 0.5 11.5 0.0 0.5 2.8 8.2 3.2 2.4 7.6 7.5 1.7 0.0 1.0 0.4 0.0 7.2 0.5 0.5 0.3 0.1 23.3 14.1 0.4 0.4 0.2 1.4 0.0 19.7 0.6 6.8 82.8 21.1 4.2 0.6 2.1 8.7 9.8 6.2 1.5 SMCHD1 "FSHD2, KIAA0650" ENSG00000101596 "Structural maintenance of chromosomes flexible hinge domain containing 1" A6NHR9 18 2655726-2805017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 363.7;Plasma cells: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 58.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039441 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 2: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies" "HPA039441: AB_10671042" "unprognostic (2.99e-2)" "unprognostic (5.14e-2)" "unprognostic (1.33e-2)" "unprognostic (9.03e-2)" "unprognostic (8.66e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (5.39e-4)" "unprognostic (1.32e-1)" "unprognostic (4.14e-2)" "unprognostic (3.11e-3)" "unprognostic (3.32e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (8.92e-2)" "unprognostic (2.63e-2)" 13.6 6.9 5.4 24.6 6.6 41.1 12.4 11.4 8.3 16.5 6.8 14.4 13.7 14.9 9.2 8.7 14.1 12.4 10.1 5.0 6.6 6.5 8.4 19.0 33.9 7.2 6.1 15.4 16.3 11.9 7.9 16.3 7.4 13.4 14.7 16.3 10.1 11.2 11.0 9.1 20.3 12.8 6.4 28.6 12.4 14.1 6.3 25.6 9.6 11.5 22.4 15.0 14.2 8.7 24.1 10.7 35.8 22.6 15.0 21.8 25.7 23.7 16.8 22.0 27.7 20.3 7.7 51.6 10.2 21.2 24.7 13.0 29.1 13.6 34.4 10.7 15.1 32.3 21.7 19.5 16.8 93.9 24.3 14.4 12.2 27.9 22.8 16.8 18.3 25.5 38.3 31.1 21.3 8.6 39.4 23.9 14.4 13.0 12.4 31.7 29.1 22.9 13.6 36.5 29.2 18.4 32.0 10.6 18.8 19.8 7.9 39.3 17.5 27.1 37.4 37.1 44.0 18.8 30.4 46.5 17.4 17.1 24.0 5.1 2.5 6.6 3.6 1.7 2.6 5.8 4.8 4.3 0.9 7.5 5.9 3.8 58.7 2.3 2.3 2.6 5.4 1.3 5.4 6.6 11.4 8.3 5.0 6.6 7.2 6.1 7.4 6.4 6.3 8.7 96.5 44.8 44.7 71.5 363.7 27.1 35.3 14.5 48.9 112.1 33.3 32.8 53.0 15.7 27.7 18.4 100.1 36.5 232.7 102.7 5.9 23.4 117.2 43.6 83.3 53.0 22.7 69.0 98.4 19.4 22.3 52.8 68.3 75.9 40.4 54.2 30.7 16.4 19.4 99.3 127.2 35.5 10.2 65.4 69.7 38.6 42.0 116.3 30.2 121.8 142.5 32.3 120.5 111.1 130.4 23.6 60.1 38.0 391.1 52.0 46.5 6.1 22.5 88.5 39.5 59.7 69.8 166.7 115.3 41.3 24.9 46.9 257.9 45.9 30.4 57.8 EMILIN2 "FLJ33200, FOAP-10" ENSG00000132205 "Elastin microfibril interfacer 2" Q9BXX0 18 2847006-2916003 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 76.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 98.0;Hofbauer cells: 61.1;Kupffer cells: 52.9;Langerhans cells: 99.7;Macrophages: 97.5;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 5.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 48.2;BEWO: 37.8;HL-60: 37.8;HMC-1: 60.6;HSkMC: 26.1;SuSa: 25.7;THP-1: 36.7;U-2197: 46.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 25.7" HPA064576 Supported "Secreted to extracellular matrix" NA NA 840000 "Cluster 41: Basophils - Cellular respiration" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "HPA064576: AB_2732717" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "unprognostic (7.91e-3)" "unprognostic (1.11e-2)" "unprognostic (3.98e-3)" "unprognostic (9.91e-3)" "prognostic unfavorable (6.30e-4)" "unprognostic (2.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (1.61e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.49e-1)" "unprognostic (3.15e-3)" "unprognostic (3.72e-2)" "unprognostic (2.96e-1)" 13.0 1.3 1.2 17.2 2.2 11.3 5.1 4.8 1.7 5.3 2.2 2.8 1.6 6.4 0.8 2.4 4.7 5.9 6.8 0.7 1.2 1.1 1.5 11.9 2.4 8.1 4.4 5.9 1.4 76.0 0.4 21.9 5.8 1.0 3.3 0.1 2.3 1.2 0.8 2.7 2.2 8.4 6.6 3.9 1.6 1.8 7.4 2.9 1.6 2.4 2.0 8.0 4.0 10.6 0.2 0.4 2.9 0.0 48.2 19.9 37.8 7.9 0.0 1.4 2.4 5.6 0.1 0.0 0.6 19.3 0.5 0.1 1.0 0.0 2.6 0.0 2.6 0.5 0.2 0.4 1.6 37.8 60.6 26.1 0.0 1.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.1 10.4 4.9 0.4 0.1 0.1 2.5 0.0 0.1 0.2 0.4 0.2 0.2 0.3 1.4 25.7 0.0 36.7 0.4 0.0 5.2 46.7 0.4 0.0 0.0 0.0 3.1 9.1 1.0 5.5 1.1 0.3 0.4 0.8 0.3 0.2 0.4 0.3 1.1 0.3 0.2 0.4 1.1 1.5 0.7 0.7 0.3 0.4 1.2 2.2 4.8 1.7 0.7 1.2 8.1 4.4 5.8 6.6 7.4 10.6 6.8 3.2 6.7 0.0 13.7 5.7 3.3 0.5 0.6 0.1 2.8 3.0 15.7 1.5 5.3 3.7 0.0 4.7 14.5 2.8 1.9 2.7 2.3 19.3 98.0 8.8 3.0 6.7 0.5 1.1 11.9 31.4 5.6 46.0 46.3 5.7 2.9 0.5 61.1 0.0 1.2 4.9 0.0 52.9 99.7 2.3 15.2 97.5 5.4 2.8 51.0 0.0 7.2 11.1 9.1 2.4 7.9 1.2 2.7 3.5 1.5 1.7 4.0 0.2 0.0 2.3 8.7 4.9 5.5 0.4 4.0 2.9 9.6 14.7 5.1 2.8 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 MYOM1 ENSG00000101605 "Myomesin 1" P52179 18 3066807-3219968 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "heart muscle: 412.8;skeletal muscle: 845.6;tongue: 435.6" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 1346.0" "Cancer enhanced" "Detected in many" "liver cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HAP1: 13.5;HMC-1: 3.5;HSkMC: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA014305, HPA049193" Enhanced NA NA 33000 "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA014305: AB_1854257, HPA049193: AB_2680670" "unprognostic (2.51e-1)" "unprognostic (2.08e-3)" "unprognostic (2.19e-3)" "unprognostic (8.01e-3)" "unprognostic (8.94e-2)" "unprognostic (4.31e-2)" "unprognostic (9.10e-2)" "unprognostic (1.59e-1)" "unprognostic (9.27e-2)" "unprognostic (1.87e-1)" "unprognostic (2.38e-1)" "unprognostic (1.63e-2)" "unprognostic (2.01e-1)" "unprognostic (9.15e-2)" "unprognostic (4.90e-2)" "unprognostic (1.73e-1)" "unprognostic (2.62e-1)" 15.1 2.2 7.5 1.3 9.0 0.6 4.1 7.8 6.4 3.0 3.4 14.1 1.9 6.4 2.9 14.1 6.8 14.6 412.8 5.7 11.5 1.5 24.7 1.5 1.3 11.1 12.0 2.9 11.5 0.4 1.6 1.6 11.3 12.4 2.4 2.0 5.3 4.5 845.6 1.6 4.6 11.9 8.6 0.9 3.2 5.7 8.0 0.8 2.8 435.6 0.7 7.6 2.4 8.6 0.0 0.1 0.2 0.0 0.7 0.7 0.3 0.4 0.5 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.0 13.5 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.0 3.5 6.2 0.3 0.2 0.0 0.3 0.0 0.2 0.0 0.4 0.2 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.4 0.1 0.2 0.0 0.6 0.0 0.2 7.5 9.0 7.8 6.4 5.7 11.5 11.1 12.0 11.3 8.6 8.0 8.6 1.2 0.0 0.5 49.0 1.7 1.7 2.3 0.7 0.0 2.1 1.0 0.8 1346.0 27.1 1.2 0.0 2.1 0.9 2.7 7.4 0.0 0.6 11.7 1.1 0.4 12.0 0.0 0.8 3.5 6.3 0.1 27.4 6.6 1.0 0.0 3.4 2.5 19.1 0.3 1.7 7.1 0.7 4.1 1.3 2.1 14.1 2.1 1.3 0.0 7.5 1.5 0.2 2.1 24.6 13.5 1.5 88.9 4.1 0.1 0.8 0.5 0.3 2.1 1.6 6.6 24.6 40.8 4.4 5.4 0.1 1.3 2.2 1.3 1.3 0.6 0.6 MYL12A "MLCB, MRCL3, MRLC3, MYL2B" ENSG00000101608 "Myosin light chain 12A" P19105 18 3247481-3256236 "Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 4234.5;skeletal muscle: 3072.7;tongue: 2082.4" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 6094.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004503, HPA039262, HPA045244, HPA059197" Supported NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB004503: AB_2282358, HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.14e-3)" "unprognostic (5.30e-2)" "unprognostic (1.80e-1)" "unprognostic (5.31e-2)" "unprognostic (3.03e-2)" "unprognostic (7.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.57e-3)" "unprognostic (2.02e-1)" "unprognostic (2.53e-2)" "unprognostic (1.49e-3)" "unprognostic (2.30e-1)" "unprognostic (9.86e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (4.58e-3)" "unprognostic (7.13e-2)" 492.0 246.2 83.6 358.2 86.6 455.0 423.8 91.2 123.7 311.2 114.1 448.8 315.2 258.1 267.0 410.9 274.7 354.6 4234.5 81.0 97.2 427.9 462.3 564.8 562.8 101.2 89.5 191.4 228.8 364.4 106.9 445.4 101.7 247.4 486.6 50.7 282.4 245.6 3072.7 280.7 332.6 317.3 97.0 566.3 369.0 106.8 93.5 461.6 314.3 2082.4 601.6 408.3 240.5 96.8 467.6 298.1 580.7 257.3 701.6 691.8 386.7 1045.3 1176.5 827.9 895.4 440.7 543.5 224.6 263.9 1412.9 627.3 192.7 360.9 601.0 736.0 326.9 129.4 236.6 297.2 360.0 1118.3 658.7 401.0 1129.5 803.3 698.0 420.0 799.7 1332.7 272.6 292.6 694.7 1748.4 793.6 282.9 571.7 253.3 496.5 199.3 167.0 341.1 384.7 1827.8 680.1 86.7 211.5 840.9 333.1 674.0 541.8 233.8 918.2 1717.0 212.6 508.4 635.5 828.0 166.9 278.8 351.6 665.5 249.5 798.1 3164.3 1120.8 2382.2 2287.2 1192.8 2280.2 1588.6 2106.9 2315.1 1639.0 1353.6 1901.6 2215.8 1785.1 1629.3 1464.6 2487.8 2068.3 4517.7 83.6 86.6 91.2 123.7 81.0 97.2 101.2 89.5 101.7 97.0 93.5 96.8 1206.6 737.2 291.0 4.6 530.9 635.9 973.5 1804.3 259.6 29.4 294.8 396.4 6094.3 449.0 949.8 511.3 12.5 748.1 1090.0 1033.5 471.6 1335.5 32.4 570.0 312.1 938.8 105.4 244.9 1.7 1487.7 1168.6 453.0 318.5 662.3 521.0 301.7 870.6 272.5 844.2 57.2 2.9 570.4 889.0 605.3 992.8 32.8 334.6 924.2 442.9 26.2 1616.2 92.6 1388.3 4.0 9.0 2236.5 977.2 396.5 207.4 817.8 758.0 757.7 673.1 42.4 571.9 378.7 757.0 78.9 166.5 262.6 545.1 666.0 1078.8 303.7 429.6 698.2 MYL12B MRLC2 ENSG00000118680 "Myosin light chain 12B" O14950 18 3261479-3278461 "Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039262, HPA045244, HPA059197" Supported NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA039262: AB_2676418, HPA045244: AB_2679269, HPA059197: AB_2683944" "unprognostic (2.55e-2)" "unprognostic (7.31e-2)" "unprognostic (5.69e-2)" "unprognostic (4.05e-2)" "unprognostic (3.66e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-2)" "unprognostic (7.65e-2)" "unprognostic (2.89e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (9.69e-4)" "unprognostic (1.18e-1)" "prognostic favorable (8.17e-5)" "unprognostic (3.38e-1)" "unprognostic (3.77e-1)" "prognostic favorable (6.62e-6)" "unprognostic (1.27e-2)" 360.1 441.4 172.7 232.6 179.2 301.8 377.8 181.2 233.2 317.9 206.8 436.4 420.1 265.9 482.9 509.1 297.0 278.9 312.6 185.2 186.5 559.9 406.1 426.9 272.3 186.2 180.1 231.7 224.3 418.7 189.7 405.2 184.9 244.1 439.6 103.9 364.9 273.0 269.7 342.1 403.5 248.4 180.4 274.1 321.4 152.9 183.3 303.8 340.5 214.7 314.8 404.3 347.9 181.5 565.6 294.1 253.8 247.3 726.9 598.1 437.1 839.9 719.9 751.9 769.3 611.7 439.0 282.5 360.1 1154.6 576.7 277.3 424.3 967.7 748.6 166.1 180.7 285.0 297.2 482.8 744.0 645.0 428.0 533.6 879.0 512.7 320.4 659.9 1128.1 283.3 247.8 266.3 971.9 1146.7 372.0 450.3 170.1 666.5 249.7 181.0 320.2 228.5 1572.8 995.6 208.1 217.4 836.3 497.2 524.7 403.6 429.2 379.3 1422.8 736.3 1111.3 654.0 1036.9 148.1 153.2 342.8 448.2 256.9 586.8 1484.7 500.6 1513.2 643.7 666.4 548.3 436.8 619.3 701.5 582.0 360.0 501.2 582.5 1141.6 485.2 799.0 797.2 742.7 1294.1 172.7 179.2 181.2 233.2 185.2 186.5 186.2 180.1 184.9 180.4 183.3 181.5 846.5 807.7 516.2 16.3 279.4 634.5 889.6 2141.6 412.6 82.6 394.7 556.9 755.3 444.7 1157.4 542.6 25.0 1084.6 470.9 1301.7 1048.7 1453.7 164.3 617.3 362.5 674.4 243.9 269.7 21.9 1470.9 1082.5 447.4 290.0 705.2 446.8 372.9 683.9 292.2 614.1 65.6 20.4 590.3 990.7 375.7 450.1 225.0 446.4 448.1 345.1 52.5 911.6 185.7 461.4 14.1 21.6 2199.0 1180.2 433.3 121.6 814.9 1459.2 1477.9 891.9 94.5 355.0 269.5 542.6 240.0 208.9 486.5 568.4 1402.6 532.9 671.1 568.9 1097.6 TGIF1 "HPE4, TGIF" ENSG00000177426 "TGFB induced factor homeobox 1" Q15583 18 3411608-3459978 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 783.4;Basal respiratory cells: 419.8;Basal squamous epithelial cells: 483.2;Urothelial cells: 426.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA062160 Supported Nucleoplasm NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA062160: AB_2684701" "unprognostic (1.11e-2)" "unprognostic (5.20e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (3.57e-3)" "unprognostic (3.10e-2)" "unprognostic (2.75e-1)" "unprognostic (4.34e-2)" "unprognostic (1.94e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (6.47e-4)" "unprognostic (9.60e-2)" "unprognostic (1.12e-2)" "unprognostic (9.81e-2)" "unprognostic (4.60e-1)" "unprognostic (7.07e-2)" "unprognostic (2.48e-3)" 51.2 40.1 21.7 43.3 20.8 41.5 57.6 22.4 25.7 68.9 30.2 51.5 31.6 51.2 133.7 46.7 74.7 65.3 29.8 20.2 29.3 74.0 61.5 47.6 26.4 29.8 27.3 67.3 46.9 26.9 22.0 63.8 25.7 54.6 65.7 8.0 56.5 56.1 34.4 60.2 37.8 37.4 27.5 35.5 49.1 25.9 25.7 40.0 66.7 26.9 27.0 112.1 40.0 28.4 33.6 148.5 92.7 29.3 90.0 121.7 235.7 63.1 236.6 49.9 62.1 61.0 142.6 1.9 20.9 49.8 165.7 33.7 35.0 73.8 61.6 13.9 16.8 4.3 73.2 110.5 178.8 47.6 38.3 89.5 291.7 89.7 233.7 131.3 104.4 22.3 36.0 0.4 95.6 65.8 31.1 58.8 240.8 119.0 34.8 32.8 43.2 10.3 198.1 156.7 27.1 26.5 166.2 123.0 92.5 151.3 28.1 43.7 49.6 77.5 65.6 92.7 41.1 5.0 0.6 15.7 78.5 18.6 98.2 65.4 42.8 7.6 62.9 16.6 67.8 46.5 52.5 61.9 35.1 32.2 37.1 43.5 19.8 21.5 16.7 3.3 32.1 36.3 21.7 20.8 22.4 25.7 20.2 29.3 29.8 27.3 25.7 27.5 25.7 28.4 41.0 35.3 40.2 8.1 106.5 359.6 783.4 419.8 483.2 0.0 114.1 72.1 5.6 100.1 128.3 123.2 0.0 161.6 60.1 30.0 49.0 117.1 41.5 167.2 58.5 66.6 46.4 25.7 2.7 75.0 220.9 102.8 79.0 240.2 68.0 71.5 29.3 35.7 71.8 1.7 0.6 99.4 136.3 44.9 221.1 9.7 28.6 126.8 76.5 7.5 71.9 6.7 11.3 4.0 1.7 106.0 53.0 15.4 15.1 308.1 24.9 113.1 93.3 0.1 32.9 90.9 86.6 7.9 15.4 223.9 257.1 150.4 103.7 8.0 91.8 426.2 DLGAP1 "DAP-1, GKAP, SAPAP1" ENSG00000170579 "DLG associated protein 1" O14490 18 3496032-4455307 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Group enriched" "Detected in many" 7 "Excitatory neurons: 2145.5;Inhibitory neurons: 3599.2;Oligodendrocyte precursor cells: 1264.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 39.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 10.7;HAP1: 3.7;U-2197: 3.3;U-87 MG: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078234 Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "HPA078234: " "unprognostic (2.50e-3)" "unprognostic (7.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-2)" "unprognostic (3.63e-3)" "unprognostic (2.73e-2)" "unprognostic (1.97e-2)" "unprognostic (2.93e-3)" "unprognostic (5.49e-3)" "unprognostic (5.87e-4)" "unprognostic (2.18e-1)" "unprognostic (2.78e-3)" "unprognostic (3.10e-2)" "unprognostic (4.93e-3)" "unprognostic (8.93e-2)" "unprognostic (9.68e-2)" 0.4 4.3 8.3 0.2 18.3 0.0 1.5 4.4 39.4 0.6 0.0 0.3 0.1 0.7 8.2 0.2 6.5 4.1 0.4 24.0 0.0 1.2 0.1 0.7 0.2 0.0 0.0 1.9 0.2 0.0 2.4 0.6 0.0 2.9 0.2 3.2 1.9 10.1 0.1 0.2 0.2 0.3 0.0 0.5 0.1 3.7 0.0 0.1 0.5 0.4 0.1 0.5 0.6 7.4 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.2 0.0 0.9 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.4 0.8 1.2 0.0 0.1 0.0 0.8 0.2 0.0 0.0 0.0 0.0 1.0 3.3 0.0 0.2 0.0 0.1 2.3 0.0 0.9 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 18.3 4.4 39.4 24.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.5 0.0 4.6 309.8 0.3 0.8 0.3 0.3 5.7 23.6 6.6 2.8 3.1 7.2 0.1 1.8 0.0 0.1 0.1 0.4 0.0 0.2 11.4 31.7 8.3 1.9 3.0 0.0 2145.5 0.2 0.1 1.8 0.5 94.6 0.0 0.0 2.2 0.0 0.2 0.0 3599.2 1.7 0.0 0.0 0.7 13.8 0.6 0.6 12.4 72.1 0.1 0.2 0.0 1264.6 31.0 0.2 0.1 0.4 0.0 3.5 0.0 5.4 4.4 1.4 0.0 0.7 2.2 12.9 4.8 1.6 0.1 0.3 0.8 0.1 0.1 0.1 AKAIN1 C18orf42 ENSG00000231824 "A-kinase anchor inhibitor 1" P0CW23 18 5142911-5197503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.2;brain: 22.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA049365 Uncertain NA NA "Cluster 6: Brain - Smell perception" "HPA049365: AB_2680729" "unprognostic (4.86e-1)" "unprognostic (1.49e-3)" "unprognostic (7.05e-2)" 0.0 10.2 2.5 0.0 1.1 0.0 0.0 22.9 14.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 11.3 1.2 0.2 1.1 0.0 0.0 3.7 2.6 0.1 0.7 0.7 2.4 0.0 2.9 0.0 0.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.8 5.9 0.0 0.1 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 1.1 22.9 14.7 11.3 1.2 3.7 2.6 2.9 1.3 5.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZBTB14 "ZFP161, ZNF478" ENSG00000198081 "Zinc finger and BTB domain containing 14" O43829 18 5289019-5297053 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050758, HPA070819" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Nucleoli, Cytosol" "HPA050758: AB_2681226, HPA070819: AB_2686316" "unprognostic (5.28e-2)" "unprognostic (4.37e-2)" "unprognostic (4.25e-2)" "unprognostic (2.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-2)" "unprognostic (2.95e-2)" "unprognostic (8.64e-2)" "unprognostic (1.19e-3)" "unprognostic (4.72e-3)" "unprognostic (3.25e-2)" "unprognostic (1.49e-1)" "unprognostic (3.70e-2)" "unprognostic (2.03e-1)" "unprognostic (2.53e-1)" "unprognostic (3.73e-1)" "unprognostic (2.90e-2)" 10.3 8.6 9.3 14.7 10.5 9.6 12.5 11.4 12.2 9.6 7.4 10.4 8.7 9.9 16.4 12.4 10.6 12.0 8.6 8.7 9.6 11.2 13.4 11.1 24.7 9.5 10.3 15.6 14.4 12.0 4.8 9.1 9.6 9.8 10.0 7.3 12.2 12.1 8.5 14.0 9.3 8.7 10.2 16.2 11.9 5.9 9.5 21.8 15.5 8.4 21.8 9.6 5.2 11.4 9.0 11.8 15.1 11.2 11.0 14.5 10.0 8.8 13.0 12.0 10.5 11.3 11.5 31.2 7.6 10.7 13.9 8.2 11.2 13.2 12.2 6.0 6.0 12.4 11.1 10.5 7.8 15.8 14.4 11.6 10.9 8.5 7.9 13.0 19.2 22.3 8.1 10.1 12.4 9.9 23.8 10.5 13.4 11.1 6.0 14.0 9.7 9.2 10.0 10.8 13.3 13.0 13.4 8.8 14.3 15.0 10.5 17.9 10.7 15.6 12.8 12.2 13.3 6.4 6.9 19.9 16.4 13.3 14.0 9.8 5.5 14.1 8.7 7.8 8.6 7.5 11.0 10.0 8.2 10.4 11.6 11.1 1.2 7.6 7.5 6.1 7.6 7.3 9.3 10.5 11.4 12.2 8.7 9.6 9.5 10.3 9.6 10.2 9.5 11.4 8.8 6.4 6.7 5.9 8.5 2.4 1.6 2.9 5.2 7.4 5.6 4.3 3.6 1.5 2.2 5.5 0.0 5.3 6.3 5.5 5.9 4.9 0.8 4.3 5.5 7.4 1.2 9.1 2.9 3.3 5.5 4.6 0.5 3.7 15.9 6.0 11.7 6.9 7.1 5.0 3.1 5.1 8.2 7.5 4.5 2.8 5.9 6.3 1.8 1.0 7.8 10.8 6.2 2.5 6.6 3.5 4.0 5.7 2.2 2.4 5.7 5.5 2.5 5.9 0.0 6.0 5.7 1.0 9.3 4.2 3.0 2.2 8.8 5.1 5.2 1.5 EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 171.9;Excitatory neurons: 306.8;Inhibitory neurons: 237.4;Late spermatids: 291.6;Oligodendrocytes: 159.2;Syncytiotrophoblasts: 214.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.4" "Lineage enriched" "Detected in many" 5 "monocytes: 12.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;HUVEC TERT2: 59.5;SCLC-21H: 65.5;TIME: 164.8;U-2 OS: 57.7;U-2197: 57.1;U-251 MG: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 27.6 28.1 5.8 27.4 5.3 4.1 11.7 17.9 49.9 6.4 0.0 17.7 49.6 7.8 5.6 10.7 13.6 9.3 6.5 7.1 24.8 33.9 4.8 13.9 7.9 59.6 14.7 11.4 6.9 59.6 10.4 21.1 53.3 5.8 13.1 45.8 4.0 7.3 6.1 4.0 47.7 13.4 7.7 12.2 3.2 62.3 29.1 6.5 4.6 10.7 3.9 10.3 5.7 29.8 0.3 0.9 3.9 0.0 54.5 62.8 43.7 12.8 0.0 0.0 0.0 0.7 0.1 0.1 0.1 39.8 23.2 0.2 38.6 0.0 0.0 0.0 34.2 0.1 0.4 0.0 0.2 0.1 4.6 33.3 0.0 12.3 0.1 16.2 59.5 0.0 0.4 0.4 0.1 0.0 0.5 0.7 7.9 0.2 12.5 0.3 0.0 0.2 0.4 4.8 65.5 0.5 0.1 0.5 25.9 31.2 0.7 4.8 164.8 0.3 57.7 57.1 71.6 0.1 0.1 0.0 0.2 5.4 6.8 0.0 4.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.7 0.0 12.4 0.0 0.0 0.7 5.8 5.3 17.9 49.9 7.1 24.8 59.6 14.7 53.3 7.7 29.1 29.8 18.2 19.2 6.4 28.7 1.3 15.9 4.1 0.0 3.4 75.6 5.3 1.7 3.5 2.8 1.9 7.3 77.2 98.6 0.2 44.0 15.6 0.4 171.9 2.2 10.1 21.9 9.1 3.2 306.8 0.7 44.2 27.7 0.0 2.1 0.0 0.0 7.1 0.8 58.8 3.3 237.4 10.0 0.0 82.2 66.7 291.6 22.4 81.9 10.6 103.0 50.9 3.3 2.1 44.2 159.2 0.8 8.3 7.9 1.6 3.8 91.2 68.4 1.6 14.7 0.0 3.0 13.1 2.7 11.5 2.3 8.4 214.0 2.6 0.2 12.3 1.7 TMEM200C TTMA ENSG00000206432 "Transmembrane protein 200C" A6NKL6 18 5882072-5895955 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.7;salivary gland: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.3;Cone photoreceptor cells: 6.2;Inhibitory neurons: 8.0;Oligodendrocyte precursor cells: 17.6" "Cancer enhanced" "Detected in single" "glioma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;NTERA-2: 4.7;PC-3: 22.0;U-2 OS: 10.9;U-251 MG: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA047253, HPA050490" Uncertain Approved Microtubules NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Microtubules "HPA047253: AB_2680001, HPA050490: AB_2681144" "unprognostic (6.57e-4)" "unprognostic (3.09e-1)" "unprognostic (1.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.29e-2)" "unprognostic (6.31e-2)" "unprognostic (3.82e-4)" "unprognostic (2.48e-10)" "unprognostic (2.94e-2)" "unprognostic (6.38e-2)" "unprognostic (7.22e-2)" "unprognostic (2.38e-2)" 0.2 3.9 2.2 0.3 2.2 0.0 0.6 0.3 2.2 0.7 0.0 0.5 0.1 0.5 1.1 0.2 0.5 0.4 2.1 1.0 2.5 1.6 1.0 0.1 0.4 2.2 7.7 0.7 0.0 0.1 2.3 0.0 2.6 0.7 0.0 0.8 5.5 0.2 0.0 0.2 0.6 0.1 2.5 0.6 0.4 0.9 2.6 0.1 0.1 0.0 0.3 0.4 0.1 0.9 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 22.0 1.3 0.0 0.0 0.0 0.0 1.1 3.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 10.9 0.0 3.9 0.0 0.0 0.0 1.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.2 0.3 2.2 1.0 2.5 2.2 7.7 2.6 2.5 2.6 0.9 0.1 0.0 1.1 0.3 0.0 0.1 0.0 0.0 0.0 9.3 0.5 2.0 2.4 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 2.0 3.4 0.1 0.7 0.0 0.0 1.6 0.0 0.1 2.2 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.0 0.0 0.0 0.4 1.1 1.2 0.2 0.0 1.0 0.0 0.8 0.0 17.6 0.1 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.0 1.4 0.3 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.1 L3MBTL4 "FLJ35936, HsT1031" ENSG00000154655 "L3MBTL histone methyl-lysine binding protein 4" Q8NA19 18 5954706-6415237 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Late spermatids: 85.8;Microglial cells: 78.7;Oligodendrocyte precursor cells: 191.5;Oligodendrocytes: 252.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 4.8;RPMI-8226: 11.6;SCLC-21H: 5.3;SH-SY5Y: 5.8;U-2 OS: 3.4" "Low region specificity" "Detected in some" "HPA064194, HPA069042" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA064194: AB_2685208, HPA069042: AB_2686071" "unprognostic (1.33e-3)" "unprognostic (8.98e-2)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-1)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" 3.0 4.3 7.1 1.8 11.5 1.6 4.9 0.2 8.4 4.3 0.6 2.1 3.0 3.2 3.6 3.6 4.2 2.5 4.9 3.8 6.8 7.1 8.8 3.9 2.0 3.3 8.2 8.5 6.5 8.5 3.2 0.7 4.7 2.0 2.0 1.7 3.4 2.9 1.0 7.3 3.5 1.3 1.6 2.9 3.2 12.7 6.6 2.9 5.8 1.3 1.6 1.4 4.1 14.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 2.4 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.2 0.0 1.4 3.1 0.0 11.6 0.0 2.0 5.3 5.8 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 3.4 0.1 1.4 0.1 0.0 0.0 1.3 0.0 1.7 0.3 1.1 0.0 0.7 0.3 0.0 0.5 0.1 0.1 0.7 2.5 0.1 0.2 0.1 3.6 0.8 0.1 0.0 0.5 7.1 11.5 0.2 8.4 3.8 6.8 3.3 8.2 4.7 1.6 6.6 14.0 6.5 3.2 12.2 56.2 4.8 7.8 7.0 0.8 10.2 2.2 4.5 4.8 6.4 11.5 4.1 5.5 16.7 0.1 2.7 0.3 3.9 7.4 62.5 8.1 1.2 3.6 11.4 0.8 33.9 5.2 0.0 3.4 1.5 16.9 1.3 15.4 2.5 10.0 3.2 0.0 160.4 1.5 0.0 3.2 5.3 85.8 10.2 2.9 1.8 78.7 27.2 1.8 25.7 191.5 252.9 3.5 1.9 12.8 1.5 10.3 3.5 8.1 1.2 0.6 6.6 6.9 7.2 9.3 2.4 6.5 8.2 0.1 2.1 0.5 2.5 4.6 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 LAMA1 LAMA ENSG00000101680 "Laminin subunit alpha 1" P25391 18 6941742-7117797 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 5.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.8;Distal enterocytes: 173.6;Granulosa cells: 77.3;Intestinal goblet cells: 44.2;Paneth cells: 35.8;Proximal enterocytes: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 56.0;ASC diff: 41.0;BEWO: 199.6;hTEC/SVTERT24-B: 41.7;SK-MEL-30: 38.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" CAB010179 Enhanced "Secreted to extracellular matrix" NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB010179: AB_2133741" "unprognostic (2.75e-1)" "unprognostic (3.66e-4)" "unprognostic (2.08e-1)" "unprognostic (3.56e-1)" "unprognostic (4.97e-3)" "unprognostic (3.66e-2)" "unprognostic (1.72e-2)" "unprognostic (7.94e-2)" "unprognostic (2.23e-2)" "unprognostic (3.43e-2)" "unprognostic (3.02e-1)" "unprognostic (6.80e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-2)" "unprognostic (4.85e-1)" "unprognostic (3.47e-2)" "unprognostic (7.34e-3)" 0.7 0.0 2.0 0.2 1.5 0.0 1.6 1.9 1.1 0.8 0.5 0.1 0.0 0.9 1.4 0.1 0.2 0.0 0.2 2.0 2.0 2.9 0.1 0.3 0.0 2.0 2.8 1.4 1.1 0.0 1.0 0.1 2.1 0.2 0.0 0.4 1.3 0.6 0.0 0.2 0.0 0.3 2.2 0.1 0.0 5.9 3.0 0.1 2.5 0.0 0.0 0.3 0.2 2.9 0.0 0.0 56.0 0.0 41.0 36.5 199.6 2.0 9.8 9.9 21.5 24.4 0.0 0.0 0.5 3.4 8.0 0.1 0.0 7.3 4.1 0.0 3.2 0.0 11.8 0.0 4.8 0.0 0.0 31.1 1.1 41.7 23.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 2.8 0.0 0.0 38.4 11.6 0.0 0.0 0.0 7.5 20.5 4.2 0.1 0.0 0.0 0.0 3.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.5 1.9 1.1 2.0 2.0 2.0 2.8 2.1 2.2 3.0 2.9 2.6 6.4 0.0 90.8 0.0 0.0 0.8 0.8 0.6 0.5 2.3 7.2 1.9 4.3 0.0 0.0 0.0 4.1 0.0 173.6 0.0 0.0 1.6 4.1 0.6 0.2 1.2 0.0 1.4 0.5 3.1 4.2 0.0 4.3 0.0 77.3 0.0 0.1 0.9 0.0 1.7 44.2 0.0 0.0 0.0 3.7 0.0 0.2 0.0 15.0 0.0 3.4 0.0 4.0 1.8 0.0 35.8 0.0 0.0 1.0 47.5 1.4 0.1 0.3 0.0 0.6 3.4 0.4 2.5 0.3 0.0 4.8 0.2 4.6 16.5 0.3 LRRC30 ENSG00000206422 "Leucine rich repeat containing 30" A6NM36 18 7231125-7232047 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 19 "skeletal muscle: 16.2;tongue: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041039 Uncertain NA NA "Cluster 33: Striated muscle - Muscle contraction" "HPA041039: AB_2677270" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 RAB12 ENSG00000206418 "RAB12, member RAS oncogene family" Q6IQ22 18 8609437-8639382 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.4;Inhibitory neurons: 46.3;Microglial cells: 45.9;Oligodendrocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040727 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040727: AB_10794858" "unprognostic (7.92e-2)" "unprognostic (4.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (1.25e-2)" "unprognostic (2.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (9.11e-2)" 36.8 26.2 27.0 17.8 29.8 13.6 27.9 31.6 33.9 28.3 21.6 34.9 11.8 29.7 19.6 28.8 26.7 18.5 85.4 30.0 31.3 31.4 36.5 30.3 20.9 25.3 27.3 31.0 13.4 21.7 21.3 30.0 25.8 22.7 16.9 22.6 18.0 29.7 193.8 31.5 20.2 34.3 28.3 28.0 19.2 12.0 32.7 15.2 19.8 106.6 20.8 29.0 25.3 27.2 33.1 19.4 22.1 23.2 64.3 54.2 12.2 44.0 60.2 49.1 57.4 26.3 29.7 11.3 41.7 53.1 36.8 20.6 25.7 47.1 59.3 4.5 20.8 9.7 20.7 27.7 59.5 12.8 9.8 53.9 65.2 36.3 45.9 50.6 60.2 10.0 15.0 15.8 48.2 35.9 14.8 12.9 14.3 113.8 18.0 10.2 53.6 10.9 48.5 43.8 36.5 25.8 33.6 45.1 57.6 31.0 13.2 19.5 50.6 56.6 33.0 57.2 67.7 10.6 6.6 9.8 42.4 11.8 37.0 4.5 0.9 1.0 0.8 1.5 1.1 1.3 0.9 0.9 0.7 1.1 1.1 1.1 1.6 1.5 2.4 1.7 1.0 0.5 27.0 29.8 31.6 33.9 30.0 31.3 25.3 27.3 25.8 28.3 32.7 27.2 34.1 12.8 19.3 31.6 3.8 6.5 1.7 1.9 2.8 15.1 11.6 12.2 96.4 1.5 8.3 3.7 6.2 1.8 7.1 1.6 3.9 2.3 0.0 8.1 14.1 16.1 5.4 3.2 41.6 1.3 1.4 14.5 4.6 7.6 6.3 9.4 16.4 16.0 1.7 11.8 46.3 2.5 2.0 16.6 12.3 0.4 3.4 9.3 3.6 45.9 4.5 14.1 2.1 23.6 43.3 3.2 1.7 4.5 2.4 6.3 2.2 5.9 7.0 7.7 0.0 13.2 13.6 1.0 1.5 4.5 8.4 1.1 4.5 12.3 3.1 4.5 MTCL1 "CCDC165, KIAA0802, SOGA2" ENSG00000168502 "Microtubule crosslinking factor 1" Q9Y4B5 18 8705661-8832778 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 90.1;intestine: 28.1;retina: 34.0" "Cell type enhanced" "Detected in many" "Early spermatids: 26.0;Excitatory neurons: 86.4;Granulosa cells: 28.9;Inhibitory neurons: 80.4;Oligodendrocyte precursor cells: 24.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 9 "cerebellum: 90.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 32.0" HPA046245 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA046245: AB_10962580" "unprognostic (2.64e-1)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.35e-1)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.01e-1)" "unprognostic (4.41e-4)" "unprognostic (1.30e-2)" "unprognostic (7.19e-2)" "unprognostic (9.95e-2)" "unprognostic (2.51e-1)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.19e-4)" "unprognostic (2.82e-1)" "unprognostic (3.67e-1)" "unprognostic (7.17e-3)" "unprognostic (1.08e-2)" 1.6 0.9 0.0 2.5 0.6 0.5 1.4 90.1 10.1 4.7 0.0 28.1 1.8 2.3 0.7 2.7 1.0 8.1 2.9 0.7 0.5 2.5 1.3 1.2 0.8 4.9 2.6 1.1 3.7 2.8 5.6 2.3 7.3 1.7 1.7 34.0 1.4 3.0 2.1 2.5 4.3 5.2 0.9 0.6 8.9 8.0 0.0 3.7 0.4 1.1 0.5 9.4 4.6 6.3 16.8 35.3 17.4 10.2 7.6 14.1 0.7 22.9 16.9 18.6 13.4 10.4 5.8 10.5 12.8 16.1 13.9 2.5 5.5 9.4 8.5 2.1 4.5 5.1 10.1 9.4 10.9 0.1 7.3 8.3 6.8 10.5 7.2 12.1 14.8 8.8 1.1 17.8 8.7 5.0 0.7 2.5 7.9 40.2 15.2 14.0 12.5 3.8 26.9 29.9 39.3 8.8 10.5 3.0 2.7 14.3 1.0 0.6 28.2 33.8 17.6 27.4 23.8 3.4 2.8 5.1 8.4 0.6 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 90.1 10.1 0.7 0.5 4.9 2.6 7.3 0.9 0.0 6.3 0.4 0.0 1.1 9.4 1.3 0.0 2.8 0.0 4.6 0.0 1.5 1.9 6.5 8.6 0.6 1.8 0.0 5.0 1.8 1.8 1.9 5.6 26.0 2.8 2.3 2.1 1.2 4.6 86.4 3.5 0.4 1.5 5.6 7.8 2.5 28.9 4.6 1.0 0.6 0.0 80.4 1.5 0.0 0.6 0.0 8.8 1.2 0.3 0.0 8.4 0.1 0.0 0.0 24.1 18.3 8.6 0.2 0.4 1.9 4.6 0.2 1.9 0.0 0.0 0.0 0.8 1.9 0.9 5.2 3.0 0.0 1.0 0.4 1.3 1.2 1.3 NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 606.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003404, HPA077896" Supported Approved Nucleoplasm,Mitochondria,Cytosol No No 7600 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "Nucleoplasm, Cytosol" "HPA003404: AB_1079466, HPA077896: AB_2686866" "unprognostic (1.18e-1)" "unprognostic (3.89e-2)" "unprognostic (2.89e-1)" "unprognostic (8.22e-2)" "unprognostic (1.32e-2)" "unprognostic (6.72e-3)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "unprognostic (6.72e-3)" "unprognostic (1.32e-3)" "unprognostic (2.39e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (5.51e-2)" "unprognostic (1.31e-1)" "unprognostic (6.56e-2)" "unprognostic (1.95e-3)" 97.4 171.6 94.3 69.2 97.4 149.8 101.7 106.8 139.7 63.9 106.0 124.2 102.3 69.7 91.1 142.6 64.0 68.7 419.3 96.7 106.0 180.7 404.2 88.6 105.0 105.9 104.4 52.4 111.6 136.7 72.1 73.7 105.9 88.5 119.8 129.9 97.4 72.4 606.9 94.7 100.5 80.6 103.7 86.4 133.8 79.6 102.7 90.2 72.7 538.3 105.1 122.1 76.5 104.6 136.5 139.8 159.1 148.4 116.6 164.0 133.4 165.4 266.5 217.7 205.5 265.1 109.4 209.4 149.5 158.6 200.3 66.9 157.5 175.5 208.8 104.6 136.6 133.0 135.3 364.8 133.6 373.8 159.2 139.2 144.3 134.9 146.2 156.8 239.3 184.3 216.5 644.0 204.6 171.6 263.5 328.9 131.4 750.5 172.3 124.5 118.2 794.2 354.3 218.7 167.0 122.3 164.6 188.0 220.3 113.6 174.2 282.8 145.8 273.4 194.3 198.8 223.0 180.4 292.3 237.1 195.4 166.0 181.0 250.8 161.8 194.2 118.1 196.1 148.3 237.6 176.9 140.5 237.9 201.1 153.5 142.7 76.0 124.2 187.9 315.1 231.9 231.8 94.3 97.4 106.8 139.7 96.7 106.0 105.9 104.4 105.9 103.7 102.7 104.6 107.3 80.1 145.8 17.6 143.1 148.0 319.0 629.4 159.4 101.2 165.0 167.3 69.9 178.7 339.5 150.8 87.6 344.1 146.6 211.0 876.5 415.2 271.5 160.3 108.2 117.3 106.5 165.4 32.9 531.4 323.3 122.0 144.3 183.9 120.3 109.7 96.4 351.5 313.5 94.2 37.3 201.7 480.1 115.7 267.1 186.2 122.1 170.2 231.3 17.8 293.2 167.1 96.8 32.2 46.5 530.3 201.2 102.0 244.9 554.3 349.9 810.6 293.4 184.2 105.2 124.0 196.3 217.4 175.0 226.5 147.6 289.4 165.7 266.7 227.3 469.0 ANKRD12 "FLJ20053, GAC-1, KIAA0874" ENSG00000101745 "Ankyrin repeat domain 12" Q6UB98 18 9136228-9285985 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040705 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA040705: AB_10673301" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-1)" "unprognostic (3.41e-3)" "unprognostic (7.25e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.71e-4)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (3.38e-1)" "unprognostic (2.39e-2)" "unprognostic (4.62e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.03e-2)" 15.8 9.3 17.1 20.5 21.4 20.5 13.7 59.9 26.0 11.1 2.2 13.0 12.9 11.8 9.5 14.4 6.2 14.6 11.9 13.9 18.4 13.0 13.8 11.5 22.4 11.2 13.4 14.1 11.9 10.5 5.9 14.1 13.2 12.2 12.0 29.8 12.3 10.6 26.7 20.2 13.4 9.1 10.4 19.9 14.5 27.7 15.8 11.4 16.4 12.3 18.5 13.5 8.0 32.3 10.1 6.7 9.0 6.0 14.2 14.5 7.3 15.3 14.2 5.4 7.4 6.1 7.6 13.9 8.7 10.6 16.4 9.1 6.8 6.0 14.5 14.8 8.1 6.4 4.7 9.0 10.5 15.0 19.7 7.6 13.1 7.7 12.4 12.2 9.2 8.0 14.7 106.4 13.2 5.7 10.1 10.2 3.4 24.7 6.8 9.0 12.6 51.1 7.1 15.8 20.9 7.7 15.0 7.4 11.1 8.0 9.2 12.4 19.9 39.5 18.1 32.1 14.4 30.8 52.0 25.9 19.4 7.9 15.2 102.0 26.4 85.1 42.4 24.1 47.9 63.6 54.9 42.0 19.2 56.2 55.9 43.4 157.3 30.4 37.2 60.6 44.0 18.3 17.1 21.4 59.9 26.0 13.9 18.4 11.2 13.4 13.2 10.4 15.8 32.3 235.1 278.9 261.5 198.5 246.9 108.2 205.9 83.3 116.7 301.0 87.5 108.5 138.6 94.4 137.7 68.0 523.3 46.3 267.2 163.1 19.6 99.7 204.9 144.3 91.9 136.8 92.7 90.7 172.1 83.5 41.1 126.8 64.2 292.9 187.2 76.3 121.7 74.0 67.8 286.0 218.1 90.4 107.8 99.7 126.2 230.9 134.8 149.3 90.7 161.1 178.2 125.5 244.1 184.5 347.4 93.0 147.1 141.4 210.1 196.8 126.1 37.0 88.5 315.4 111.7 173.2 150.0 239.5 152.8 70.9 96.0 78.1 298.3 63.0 71.0 170.7 TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.2;Peritubular cells: 95.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" No No 3500000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centrosome, Cytosol" "HPA014898: AB_1858467" "unprognostic (2.55e-1)" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (8.95e-3)" "unprognostic (2.92e-3)" "unprognostic (1.83e-1)" "unprognostic (8.29e-2)" "unprognostic (5.88e-2)" "unprognostic (6.33e-2)" "unprognostic (1.05e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" 23.7 19.5 7.7 16.7 9.6 8.2 17.5 9.2 12.2 40.6 12.7 22.1 11.1 51.3 45.8 26.1 30.5 36.3 18.6 7.4 9.2 36.3 10.0 19.7 11.8 10.5 9.4 32.3 9.7 33.2 9.8 24.8 10.4 43.0 22.4 5.7 11.1 64.6 5.7 12.9 12.5 80.1 9.7 13.6 14.9 11.8 8.9 7.0 34.9 16.5 14.9 34.7 16.2 11.0 57.3 19.9 57.6 28.6 111.2 99.7 26.6 107.2 132.4 57.6 81.9 21.2 73.5 8.2 52.7 142.5 37.4 19.5 57.1 42.4 105.3 22.0 15.4 14.7 15.9 10.8 98.7 10.8 29.4 102.0 34.1 48.3 23.3 78.7 90.8 7.8 22.7 14.6 149.2 17.0 11.9 13.2 18.9 33.6 16.1 20.7 58.7 5.0 65.7 75.2 7.4 20.0 83.3 23.1 22.9 23.9 26.1 25.0 75.6 104.9 52.4 99.5 67.5 21.2 20.1 15.1 64.5 14.9 37.9 8.3 2.7 4.0 4.3 1.5 2.8 2.1 2.0 4.5 5.5 1.6 2.3 4.8 1.2 2.9 0.5 5.3 1.0 2.1 7.7 9.6 9.2 12.2 7.4 9.2 10.5 9.4 10.4 9.7 8.9 11.0 9.0 25.6 18.4 13.1 8.1 39.6 21.3 18.5 51.2 4.8 18.5 11.6 7.8 10.0 21.0 75.4 0.0 6.3 12.1 12.1 1.9 9.1 141.2 13.3 38.6 18.1 6.0 9.9 28.0 7.6 18.3 61.9 10.2 23.4 6.3 31.6 17.2 7.5 16.0 3.3 31.0 8.2 57.0 9.4 30.1 30.7 37.6 12.2 23.2 17.8 15.3 16.1 7.2 29.1 31.6 9.2 10.7 95.2 17.8 46.3 1.3 12.6 12.4 5.0 72.3 28.9 56.6 24.6 9.6 26.6 26.9 4.7 10.1 20.4 12.2 27.1 RALBP1 "RIP, RIP1, RLIP76" ENSG00000017797 "RalA binding protein 1" Q15311 18 9475009-9538114 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transport "GTPase activation, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Collecting duct cells: 480.1;Extravillous trophoblasts: 518.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 195.6" "Lineage enriched" "Detected in all" 10 "granulocytes: 195.6" "Cell line enhanced" "Detected in all" "OE19: 239.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046010, HPA046651" Approved Approved "Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Nuclear membrane, Vesicles" "CAB046010: AB_11126824, HPA046651: AB_2679738" "unprognostic (1.23e-1)" "unprognostic (5.84e-3)" "unprognostic (1.58e-1)" "unprognostic (1.74e-2)" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (5.72e-2)" "unprognostic (9.90e-2)" "unprognostic (1.53e-1)" "prognostic favorable (8.47e-4)" "unprognostic (4.03e-3)" "unprognostic (1.76e-1)" "prognostic favorable (5.39e-6)" "unprognostic (1.28e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (1.26e-1)" 29.7 20.4 42.7 23.4 44.1 30.7 27.8 45.8 82.2 26.8 38.6 34.1 18.7 22.1 23.5 50.3 24.8 20.3 28.5 40.7 45.1 42.7 19.9 22.6 24.0 44.1 48.0 26.3 15.4 47.9 16.8 31.4 44.4 32.6 25.4 13.5 25.0 48.2 38.5 75.9 20.4 21.1 43.6 26.5 25.7 13.0 45.3 29.3 22.9 32.5 25.4 33.8 33.3 45.1 58.9 37.6 34.2 39.0 38.3 60.7 43.3 67.7 38.1 35.6 38.0 42.6 57.5 70.5 47.0 64.8 50.2 32.8 48.1 52.7 44.2 71.4 38.5 38.5 34.6 32.7 31.2 114.8 43.0 42.0 52.2 49.6 48.7 47.7 60.6 64.6 53.7 67.7 56.2 46.3 70.7 50.9 25.4 239.5 31.9 93.6 59.4 54.2 48.4 80.7 44.7 34.8 58.2 52.8 30.9 52.3 32.9 53.8 67.4 105.0 76.9 72.3 81.9 38.7 42.9 77.9 45.6 53.4 40.5 13.0 9.6 15.7 10.3 10.6 8.7 9.9 8.7 8.8 8.7 7.5 7.3 9.4 195.6 14.8 17.8 19.8 6.4 4.5 42.7 44.1 45.8 82.2 40.7 45.1 44.1 48.0 44.4 43.6 45.3 45.1 101.8 57.7 35.7 15.3 48.0 156.4 80.9 59.9 112.7 42.6 96.0 102.2 64.8 88.6 64.6 480.1 29.2 104.2 70.9 122.6 123.3 119.4 16.1 99.1 82.6 86.9 74.2 175.7 25.4 90.7 518.6 71.6 56.1 179.4 40.5 85.8 78.9 88.3 70.1 52.2 26.7 87.7 109.9 92.8 69.7 9.5 72.7 78.4 58.7 20.6 99.6 47.6 83.4 17.1 25.3 166.3 78.2 87.3 63.2 174.4 61.0 115.0 38.6 37.3 65.7 76.8 105.6 66.7 80.0 149.6 242.5 44.6 62.6 128.4 90.1 216.4 PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA040905: AB_10794869, HPA041089: AB_10805836" "unprognostic (1.76e-1)" "unprognostic (5.33e-2)" "unprognostic (1.40e-2)" "unprognostic (5.14e-2)" "unprognostic (3.74e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-3)" "unprognostic (9.36e-2)" "unprognostic (1.16e-2)" "unprognostic (4.00e-3)" "unprognostic (3.13e-3)" "unprognostic (4.15e-1)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" 20.7 16.2 16.7 16.8 19.1 32.0 18.8 18.7 17.8 27.2 19.1 24.7 23.2 20.8 17.1 70.7 21.1 20.7 20.7 15.6 17.4 19.6 15.3 34.6 13.0 17.7 17.2 17.0 19.9 23.5 11.7 29.0 17.7 16.6 19.7 13.3 23.3 16.9 16.2 26.1 26.1 23.3 16.9 18.4 24.4 35.7 17.0 19.9 18.7 17.4 24.9 40.7 35.7 20.6 70.3 48.5 115.0 31.6 22.3 33.7 58.3 66.9 44.7 64.9 62.3 44.1 39.6 34.0 47.6 66.1 55.0 29.4 54.0 99.4 87.0 39.8 21.8 32.2 35.0 32.0 34.7 83.0 46.7 30.3 62.8 56.1 52.9 48.5 75.3 22.6 47.5 29.8 70.9 34.5 58.1 31.7 46.1 97.5 30.3 71.5 69.2 21.4 54.6 96.5 33.6 39.5 79.3 35.3 26.4 73.3 19.3 31.5 81.3 113.6 70.2 59.3 83.5 26.5 39.7 60.7 42.5 34.0 52.5 14.6 6.1 10.9 3.9 4.7 5.0 3.8 4.3 3.9 7.0 1.8 1.4 3.2 36.1 4.1 4.7 2.9 4.6 3.5 16.7 19.1 18.7 17.8 15.6 17.4 17.7 17.2 17.7 16.9 17.0 20.6 26.4 99.3 76.1 35.9 11.9 40.4 26.5 30.8 42.7 19.6 20.7 14.7 21.4 7.2 55.4 22.0 10.4 27.0 12.0 31.2 5.9 23.8 77.3 48.1 26.7 29.5 17.4 15.6 43.0 34.9 15.9 19.3 45.3 54.0 3.8 27.0 26.0 12.2 16.8 33.7 54.9 16.4 8.2 19.6 16.7 57.2 17.4 20.7 14.2 34.7 20.5 10.6 13.4 61.9 66.5 49.8 16.2 11.7 10.8 21.0 23.7 10.0 58.9 19.3 13.1 16.5 22.1 20.4 12.3 52.0 42.5 23.0 12.9 9.2 13.6 68.4 RAB31 Rab22B ENSG00000168461 "RAB31, member RAS oncogene family" Q13636 18 9708275-9862551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 180.9;Kupffer cells: 283.8;Langerhans cells: 208.9;Macrophages: 221.6;monocytes: 193.2;Oligodendrocyte precursor cells: 184.0;Syncytiotrophoblasts: 186.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 137.9" "Group enriched" "Detected in many" 8 "dendritic cells: 44.9;granulocytes: 137.9;monocytes: 51.6" "Cell line enhanced" "Detected in many" "GAMG: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019717 Approved NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "HPA019717: AB_10601493" "unprognostic (4.61e-2)" "unprognostic (1.65e-2)" "unprognostic (8.53e-2)" "unprognostic (1.13e-1)" "unprognostic (1.23e-2)" "unprognostic (5.70e-2)" "unprognostic (3.07e-2)" "unprognostic (5.99e-2)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.26e-2)" "unprognostic (3.98e-3)" "unprognostic (8.71e-3)" "unprognostic (1.61e-1)" "unprognostic (6.34e-2)" 35.0 104.8 83.1 42.2 90.5 59.7 22.2 89.1 92.6 85.2 67.7 45.8 11.1 56.2 9.4 31.8 28.8 45.6 20.9 75.9 93.1 16.3 10.5 58.9 22.4 96.6 95.1 44.2 7.0 8.6 10.0 56.5 96.8 21.3 17.7 12.6 13.7 48.7 5.4 12.9 23.7 85.8 91.5 31.3 31.7 42.6 99.3 9.8 25.9 10.5 22.6 54.5 35.2 92.1 2.7 14.4 105.0 0.2 136.7 70.5 74.6 25.4 71.0 18.2 15.8 4.1 14.4 0.1 16.6 99.7 175.3 9.9 25.9 32.6 21.1 6.5 14.6 89.3 104.4 1.8 158.0 7.4 94.2 76.5 6.6 42.1 32.5 78.0 47.4 0.0 22.2 0.4 42.6 11.9 0.1 11.5 22.2 1.2 6.3 0.1 11.5 3.7 13.9 0.3 2.0 6.8 96.4 60.7 34.7 87.5 6.9 48.4 51.9 112.9 56.4 78.3 37.5 19.4 5.7 0.1 153.7 0.1 47.1 137.9 51.6 21.3 0.1 47.2 0.1 9.8 0.2 0.1 44.9 6.7 0.1 0.1 74.4 4.3 50.2 5.2 0.2 19.5 83.1 90.5 89.1 92.6 75.9 93.1 96.6 95.1 96.8 91.5 99.3 92.1 10.0 176.3 33.3 91.4 32.4 15.8 17.7 30.8 23.3 3.2 13.2 12.6 10.6 12.8 51.2 11.0 0.0 180.9 11.0 8.7 7.9 7.9 5.4 10.2 86.0 33.1 0.0 2.5 8.1 19.6 19.0 55.5 5.6 6.2 7.6 72.9 30.0 1.9 157.0 151.4 19.6 0.6 8.2 283.8 208.9 10.9 17.7 221.6 7.2 75.9 193.2 21.5 4.1 184.0 7.0 19.4 1.4 117.4 12.0 27.3 0.0 4.0 47.0 3.9 39.5 14.0 87.3 1.7 4.2 14.5 16.1 186.6 5.1 36.3 0.3 38.8 TXNDC2 SPTRX1 ENSG00000168454 "Thioredoxin domain containing 2" Q86VQ3 18 9885726-9889275 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 311 "testis: 105.2" "Group enriched" "Detected in some" 98 "Early spermatids: 307.9;Late spermatids: 125.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 1.5;U-2 OS: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016414, HPA018817" Enhanced NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "CAB016414: , HPA018817: AB_2241329" "unprognostic (1.21e-2)" "unprognostic (3.55e-3)" "unprognostic (6.31e-2)" "unprognostic (5.25e-2)" "unprognostic (1.33e-1)" "unprognostic (1.25e-1)" "unprognostic (6.13e-1)" "unprognostic (1.21e-1)" "unprognostic (3.17e-2)" "unprognostic (8.95e-3)" "unprognostic (3.75e-2)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (1.71e-1)" "unprognostic (2.18e-2)" 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 105.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.2 0.1 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.3 0.0 0.6 0.0 0.8 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.5 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.4 0.2 1.1 0.5 0.3 0.0 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 307.9 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 125.1 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 VAPA "hVAP-33, VAP-A" ENSG00000101558 "VAMP associated protein A" Q9P0L0 18 9914016-9960021 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009174 Approved Enhanced "Endoplasmic reticulum" NA NA 580000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Endoplasmic reticulum" "HPA009174: AB_1080549" "unprognostic (4.03e-2)" "unprognostic (7.47e-2)" "unprognostic (9.36e-2)" "unprognostic (5.20e-2)" "unprognostic (2.00e-1)" "unprognostic (2.99e-2)" "unprognostic (4.79e-3)" "unprognostic (1.80e-1)" "unprognostic (5.39e-2)" "unprognostic (6.80e-3)" "unprognostic (2.99e-2)" "unprognostic (8.11e-2)" "prognostic favorable (5.72e-7)" "unprognostic (1.03e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-1)" "unprognostic (5.77e-2)" 33.1 67.1 21.5 24.2 26.8 97.1 29.5 30.7 28.1 30.2 21.5 38.6 31.2 32.9 24.8 47.5 29.3 31.9 37.5 23.2 24.9 32.6 36.6 33.9 25.7 34.9 26.3 39.1 40.9 36.2 17.7 29.8 34.5 24.5 35.4 20.1 32.6 22.0 69.7 32.3 30.6 27.4 27.8 26.7 38.9 29.1 25.5 30.0 35.2 38.4 26.3 36.5 32.2 30.7 58.1 34.4 40.7 26.7 46.9 50.5 56.8 69.9 57.9 62.3 67.9 46.6 55.9 56.5 63.6 61.5 53.9 39.7 39.8 66.7 70.7 35.6 49.8 92.4 33.8 72.3 110.8 126.3 169.7 47.8 66.3 59.0 69.6 48.7 64.0 45.4 94.6 57.3 55.2 31.2 97.4 72.9 26.2 197.6 54.3 50.4 55.2 77.5 60.9 57.3 57.2 31.2 81.1 48.7 53.2 37.2 45.7 64.2 68.9 100.7 75.3 105.6 86.3 101.9 89.2 66.6 57.0 53.5 70.8 131.3 143.3 251.0 69.8 127.9 82.9 100.0 72.1 75.4 118.1 94.4 78.1 72.1 226.2 90.8 109.5 84.6 98.9 183.9 21.5 26.8 30.7 28.1 23.2 24.9 34.9 26.3 34.5 27.8 25.5 30.7 173.6 128.2 178.8 63.0 160.0 673.4 358.4 356.5 278.3 113.9 248.2 179.3 218.3 167.3 229.4 207.8 62.6 296.9 148.0 427.2 457.8 291.8 10.5 235.9 182.2 232.4 144.6 188.1 91.4 361.3 321.6 221.4 156.0 255.8 225.2 220.2 211.3 141.1 287.8 136.3 93.2 180.6 390.6 288.2 459.8 21.7 182.0 285.9 279.3 63.7 350.4 124.3 108.1 102.1 150.4 310.2 262.7 216.3 146.6 335.4 255.9 390.4 265.5 79.5 190.7 204.8 371.4 231.3 201.4 267.3 622.5 452.6 190.2 253.6 201.0 390.8 APCDD1 B7323 ENSG00000154856 "APC down-regulated 1" Q8J025 18 10454635-10489949 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 129.8" "Cell type enhanced" "Detected in many" "Astrocytes: 120.5;Cholangiocytes: 85.8;Endometrial stromal cells: 429.5;Melanocytes: 80.0;Oligodendrocyte precursor cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;BJ hTERT+: 70.4;HaCaT: 43.0;HHSteC: 18.9;HSkMC: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.39e-4)" "prognostic favorable (8.23e-4)" "unprognostic (5.61e-3)" "unprognostic (6.79e-3)" "unprognostic (1.24e-1)" "unprognostic (5.59e-3)" "unprognostic (2.59e-2)" "unprognostic (3.14e-1)" "unprognostic (7.77e-2)" "unprognostic (2.04e-3)" "unprognostic (1.77e-1)" "unprognostic (3.06e-2)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" 52.5 14.2 33.4 6.9 31.1 0.4 31.4 30.4 34.3 35.6 17.0 12.8 3.5 32.7 15.6 27.7 32.6 21.9 32.0 39.5 33.0 6.2 1.4 13.2 1.2 33.0 36.9 33.0 8.9 3.4 3.2 26.9 29.8 33.3 13.2 1.6 10.6 14.1 7.3 129.8 14.5 10.6 26.6 4.1 23.8 2.7 33.8 2.2 5.3 18.5 4.7 36.6 35.5 29.6 0.0 0.0 32.0 0.0 5.4 0.0 0.1 2.4 70.4 3.1 4.9 0.1 0.1 0.0 0.0 13.0 0.0 43.0 0.3 0.0 3.3 0.0 1.6 0.1 0.2 0.7 18.9 0.0 0.0 39.3 1.4 6.1 0.0 0.0 0.5 0.0 0.0 0.1 3.1 2.1 1.8 0.5 5.2 15.3 0.0 0.9 0.0 1.2 0.0 0.4 0.8 0.3 0.0 0.0 3.6 2.0 0.0 0.4 0.0 3.8 0.0 0.0 0.3 0.4 0.0 0.1 0.2 0.0 4.8 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.2 33.4 31.1 30.4 34.3 39.5 33.0 33.0 36.9 29.8 26.6 33.8 29.6 3.1 0.0 12.6 120.5 0.4 65.6 3.6 3.6 11.4 4.1 14.1 20.4 4.2 85.8 2.7 3.7 0.0 2.4 1.7 0.1 0.0 11.2 0.7 28.7 429.5 47.1 3.6 0.0 0.2 0.4 0.4 64.4 0.5 10.9 1.3 0.4 1.8 0.2 1.3 0.0 2.1 1.1 2.0 0.3 35.0 0.8 8.7 3.3 80.0 67.5 1.3 0.2 0.0 110.1 15.3 0.2 0.0 37.6 1.6 11.7 0.1 0.1 5.9 2.2 26.3 18.7 28.1 0.3 1.4 13.1 53.8 1.0 4.2 1.3 1.4 4.5 NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Approved "Plasma membrane" NA NA 8800 "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA008208: AB_1854305, HPA011389: AB_1854306" "unprognostic (1.23e-1)" "unprognostic (7.64e-3)" "unprognostic (6.96e-2)" "unprognostic (1.53e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (1.46e-3)" "unprognostic (5.85e-2)" "prognostic favorable (8.14e-4)" "unprognostic (3.81e-2)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (6.96e-2)" 11.3 14.8 18.4 9.7 18.6 7.2 11.8 21.1 25.3 10.5 13.9 11.9 9.3 10.7 12.0 12.1 11.0 13.4 19.9 25.9 20.8 16.4 13.6 9.7 9.6 30.3 20.1 7.5 12.6 12.4 9.9 13.9 32.6 13.7 13.7 12.6 11.7 10.7 10.2 9.9 10.7 11.8 19.4 9.4 13.7 7.4 20.1 9.0 14.5 14.6 11.2 14.3 10.1 21.7 9.4 5.6 9.6 8.3 27.1 18.4 14.0 19.8 28.1 19.0 24.0 12.4 14.1 12.3 15.5 27.3 17.4 9.0 12.7 17.7 26.9 11.0 7.8 9.2 9.8 12.8 25.9 26.0 16.6 20.3 20.6 21.8 16.2 12.4 18.0 16.0 15.1 29.0 28.2 13.2 20.0 11.1 7.7 72.3 8.3 8.7 15.8 21.2 22.5 22.0 38.3 10.1 16.1 16.9 23.1 15.5 7.7 17.2 20.5 29.8 14.4 27.8 21.2 18.8 20.4 13.6 20.1 17.7 14.2 12.5 4.9 14.1 5.1 6.1 4.7 7.5 4.1 5.2 3.8 3.3 5.6 4.8 8.1 5.8 6.1 4.1 4.4 3.1 18.4 18.6 21.1 25.3 25.9 20.8 30.3 20.1 32.6 19.4 20.1 21.7 32.2 28.9 34.7 33.6 29.1 24.3 31.1 26.9 21.6 62.0 21.8 17.4 35.1 21.5 27.5 27.6 12.5 23.6 32.9 30.8 41.1 53.3 18.1 27.9 33.2 23.4 23.4 33.2 68.5 42.5 30.3 25.3 28.5 49.5 45.0 13.6 20.0 21.7 25.4 45.4 53.8 22.3 28.5 22.1 16.1 4.6 7.8 24.5 26.6 30.9 22.4 31.3 22.6 34.7 52.9 77.7 34.1 21.1 36.2 34.8 20.8 39.5 20.8 34.0 26.3 30.5 29.6 26.6 39.9 30.8 21.2 45.1 26.2 28.4 19.0 56.5 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 SLC35G4 "AMAC1L1, SLC35G4P" ENSG00000236396 "Solute carrier family 35 member G4" P0C7Q5 18 11609596-11610612 "Predicted membrane proteins, Transporters" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GNAL ENSG00000141404 "G protein subunit alpha L" P38405 18 11689264-11885685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 99.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.9;Inhibitory neurons: 119.5;Oligodendrocyte precursor cells: 58.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 99.0" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 26.4;HeLa: 27.4;U-2 OS: 13.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 14 "basal ganglia: 164.1" "CAB015464, HPA051160" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "CAB015464: AB_831819, HPA051160: AB_2732564" "unprognostic (2.29e-3)" "unprognostic (7.43e-2)" "unprognostic (8.14e-3)" "unprognostic (3.41e-5)" "unprognostic (4.71e-2)" "unprognostic (9.58e-3)" "unprognostic (9.93e-3)" "unprognostic (1.87e-1)" "unprognostic (2.36e-1)" "unprognostic (7.17e-2)" "unprognostic (1.82e-3)" "unprognostic (6.05e-2)" "unprognostic (1.23e-3)" "unprognostic (1.09e-1)" "unprognostic (3.85e-2)" "unprognostic (4.26e-2)" "unprognostic (7.03e-2)" 7.7 1.5 29.2 2.9 99.0 0.8 4.1 3.5 36.7 7.3 0.0 7.1 1.5 6.6 2.2 8.0 3.9 4.6 3.5 39.6 16.7 4.0 2.0 2.7 4.9 8.3 8.9 2.9 1.8 4.8 16.3 2.8 6.8 9.3 3.6 4.1 4.7 17.0 21.7 7.2 3.2 7.5 1.9 2.9 3.1 6.5 14.4 4.3 7.8 13.1 5.5 13.2 7.0 4.8 0.7 8.7 10.3 0.7 0.8 0.2 1.2 0.1 0.4 0.7 0.0 9.2 1.6 26.4 1.6 0.1 5.7 0.4 9.7 8.1 0.0 5.6 9.0 0.2 27.4 5.2 0.1 0.3 0.6 1.2 11.9 0.0 0.2 0.4 0.0 0.3 2.4 0.3 0.3 0.3 0.3 0.8 8.4 7.2 0.2 0.2 1.4 0.2 0.6 0.3 9.4 0.2 12.3 0.6 3.0 2.3 0.2 0.3 1.5 1.1 13.2 0.5 2.6 0.5 0.3 0.1 0.5 0.3 0.3 0.6 0.0 0.1 1.3 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.6 0.6 0.1 0.0 0.0 0.0 0.5 29.2 99.0 3.5 36.7 39.6 16.7 8.3 8.9 6.8 1.9 14.4 4.8 4.3 3.2 5.9 17.0 1.1 10.6 11.6 6.6 10.2 7.2 2.4 8.9 3.6 0.0 8.0 3.7 16.7 0.5 13.8 3.2 1.9 0.4 4.2 1.7 3.6 5.7 0.0 0.0 76.9 3.0 3.5 7.2 1.5 3.8 5.7 3.2 1.8 1.9 0.9 3.3 119.5 0.6 30.5 0.8 5.2 2.7 0.9 2.3 14.2 8.4 0.0 1.1 21.6 58.8 3.7 1.2 1.9 3.0 1.7 6.8 1.5 5.0 10.4 3.9 6.6 14.5 10.9 4.3 10.5 11.5 7.5 0.5 2.9 0.3 1.4 15.0 CHMP1B "C18orf2, CHMP1.5, Vps46B" ENSG00000255112 "Charged multivesicular body protein 1B" Q7LBR1 18 11851413-11854444 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "skeletal muscle: 361.4" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 514.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061997, HPA062896" Supported Approved Nucleoplasm,Midbody Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Midbody Nucleoplasm "HPA061997: AB_2684653, HPA062896: AB_2684898" "unprognostic (6.73e-2)" "unprognostic (5.35e-2)" "unprognostic (1.09e-2)" "unprognostic (6.74e-3)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" "unprognostic (1.44e-1)" "unprognostic (8.44e-3)" "unprognostic (1.90e-1)" "unprognostic (9.44e-3)" "unprognostic (2.37e-3)" "unprognostic (9.20e-2)" "prognostic favorable (7.37e-8)" "unprognostic (1.88e-2)" "unprognostic (1.59e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-1)" 43.3 35.7 24.5 36.2 25.9 61.2 29.0 19.6 25.4 25.6 30.0 39.1 38.7 28.3 26.2 39.1 24.8 39.3 40.7 25.9 25.6 33.1 31.1 29.7 29.9 21.9 23.2 29.6 24.8 39.9 29.3 27.8 22.6 27.8 37.5 17.6 29.5 35.0 361.4 40.4 48.8 23.6 20.3 30.2 30.5 14.0 24.0 46.0 52.2 53.2 24.8 49.5 23.8 23.6 30.0 28.8 36.5 31.1 46.9 32.7 52.9 31.4 52.6 21.0 27.9 37.5 29.4 18.5 45.9 34.2 35.0 25.0 16.8 43.7 18.5 17.2 20.8 13.5 43.6 31.1 34.6 51.7 22.3 47.7 92.5 23.5 53.9 46.8 30.7 41.6 23.1 23.4 33.3 37.3 36.1 39.6 15.3 94.9 14.3 18.4 18.8 32.1 56.5 40.5 35.5 35.5 53.1 24.7 50.5 33.9 20.2 47.2 45.2 46.7 24.5 37.3 34.0 27.8 34.3 23.5 43.3 23.8 22.7 32.5 38.8 66.7 15.4 35.7 14.3 14.7 14.3 18.5 30.2 14.7 17.6 16.4 77.9 18.3 36.6 26.7 21.5 29.2 24.5 25.9 19.6 25.4 25.9 25.6 21.9 23.2 22.6 20.3 24.0 23.6 71.2 67.3 47.0 0.0 152.9 419.6 141.8 291.8 216.9 30.5 71.3 59.4 21.7 52.9 157.7 132.4 8.4 135.9 171.0 281.4 60.7 123.0 80.4 146.6 110.2 69.9 143.8 40.4 0.0 80.3 144.4 99.3 70.8 298.3 149.9 38.4 52.8 44.1 118.0 28.6 0.0 104.6 111.9 139.9 440.8 42.6 37.9 354.5 158.3 0.0 102.1 32.2 78.2 0.0 0.0 134.0 393.7 37.2 21.8 93.9 179.2 139.1 84.8 16.8 78.9 61.2 94.5 16.0 21.1 177.1 514.7 253.2 135.5 43.9 96.8 252.2 MPPE1 "Cdc1, PGAP5" ENSG00000154889 "Metallophosphoesterase 1" Q53F39 18 11882622-11908366 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, GPI-anchor biosynthesis, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 100.8;neutrophil: 293.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 293.9" "Cell line enhanced" "Detected in all" "OE19: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012639 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus" "HPA012639: AB_1854088" "unprognostic (9.23e-2)" "unprognostic (1.54e-1)" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.00e-2)" "unprognostic (4.46e-1)" "unprognostic (1.61e-1)" "prognostic favorable (6.45e-7)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" "unprognostic (6.15e-2)" 14.9 13.1 11.3 20.0 11.7 28.3 15.4 11.0 11.9 16.1 11.7 21.5 17.7 17.0 20.6 17.2 16.4 21.8 18.6 10.9 11.9 28.8 23.8 25.6 16.0 12.6 11.8 12.7 31.8 20.1 15.0 14.1 12.5 16.3 21.4 15.9 15.0 19.0 23.5 29.0 20.3 15.8 10.6 15.9 22.8 8.5 12.1 16.0 47.1 11.7 14.7 14.9 13.7 13.1 7.8 11.1 8.4 19.9 22.9 26.7 7.9 18.6 26.0 10.6 16.5 20.8 21.6 15.8 39.2 17.6 10.7 8.6 5.8 10.1 9.9 17.7 10.4 4.6 22.9 4.9 31.9 20.3 30.9 40.1 13.3 9.4 6.6 15.7 6.5 13.9 5.8 14.5 17.8 18.1 15.1 13.6 5.6 65.9 3.1 6.0 5.4 18.8 17.2 11.9 11.8 6.7 17.1 13.5 16.0 9.3 9.8 25.9 13.5 21.4 8.3 20.5 10.3 22.6 21.5 19.7 15.8 10.4 21.5 20.6 42.9 100.8 24.8 34.5 18.1 17.9 15.2 23.9 37.3 21.7 18.5 23.8 293.9 29.2 24.6 29.6 27.0 31.8 11.3 11.7 11.0 11.9 10.9 11.9 12.6 11.8 12.5 10.6 12.1 13.1 19.3 57.7 33.0 13.4 24.5 18.0 16.2 20.7 12.5 17.4 14.6 11.6 2.4 24.3 23.1 22.0 12.5 27.9 35.7 43.9 21.5 30.5 20.5 17.9 14.8 15.5 9.6 13.3 20.9 41.9 32.5 16.6 29.6 22.6 27.8 23.5 15.7 27.6 25.4 8.4 21.4 23.4 14.2 33.2 25.7 36.0 12.8 24.8 19.6 20.6 24.2 23.3 52.5 12.5 24.4 36.3 18.4 15.1 16.0 10.1 36.3 27.0 26.7 20.5 13.1 17.2 13.9 7.0 8.7 21.8 20.0 16.7 33.7 16.4 16.1 22.0 IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 359.1;skeletal muscle: 257.1" "Cell type enhanced" "Detected in many" "Distal tubular cells: 440.3;Extravillous trophoblasts: 272.2;Proximal tubular cells: 498.6;Squamous epithelial cells: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.3" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.3;monocytes: 11.4" "Cell line enhanced" "Detected in many" "BEWO: 258.2;OE19: 299.8;SiHa: 155.1" "Low region specificity" "Detected in all" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Mitochondria "HPA029561: AB_10601932" "unprognostic (1.16e-1)" "unprognostic (1.28e-2)" "unprognostic (4.76e-3)" "unprognostic (2.50e-2)" "unprognostic (4.25e-2)" "unprognostic (3.25e-3)" "unprognostic (4.26e-3)" "unprognostic (4.08e-2)" "unprognostic (1.87e-1)" "unprognostic (1.96e-2)" "unprognostic (4.56e-2)" "unprognostic (4.24e-3)" "prognostic favorable (0.00e+0)" "unprognostic (1.95e-1)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (3.35e-2)" 19.8 11.1 2.5 12.3 3.2 31.5 14.8 1.8 4.4 31.0 5.3 50.0 22.4 16.2 1.7 131.2 16.3 19.9 29.5 2.5 2.4 129.4 47.4 23.2 5.7 2.2 2.4 7.8 359.1 5.3 11.1 22.0 2.1 13.7 30.7 0.8 31.0 5.9 257.1 150.0 29.2 15.6 2.3 19.0 53.7 2.9 2.6 5.0 17.4 89.8 7.3 61.0 50.8 2.3 29.3 41.7 11.3 20.4 14.1 10.5 258.2 7.2 18.4 2.9 4.2 35.4 21.7 6.1 17.4 10.1 24.1 19.8 13.2 6.9 0.8 33.5 22.5 0.0 56.0 30.6 8.3 47.5 2.3 23.9 36.3 10.0 5.2 8.5 3.9 30.7 7.4 0.0 10.7 31.8 19.4 27.1 40.5 299.8 42.7 36.0 29.6 28.6 122.1 15.6 15.0 0.3 155.1 35.8 16.2 14.5 33.3 58.5 0.0 5.6 11.5 73.7 7.3 24.5 66.3 17.9 24.0 31.7 9.6 9.4 11.4 26.0 0.7 8.7 0.3 1.5 0.7 0.2 9.0 0.3 0.3 0.5 31.3 0.1 5.8 6.7 1.1 3.1 2.5 3.2 1.8 4.4 2.5 2.4 2.2 2.4 2.1 2.3 2.6 2.3 9.2 19.2 32.7 17.6 7.8 105.5 22.7 32.1 159.4 0.7 16.8 20.2 11.6 72.9 16.1 22.0 0.0 52.5 5.8 72.9 440.3 83.4 2.8 5.7 20.2 6.9 17.5 15.3 4.7 110.6 272.2 16.1 65.2 30.4 2.5 13.4 10.0 66.8 42.5 0.0 1.8 90.2 65.1 37.7 17.0 7.1 4.7 34.2 14.2 5.6 25.5 22.3 2.1 0.5 0.5 56.1 50.1 3.8 8.6 42.9 36.9 498.6 12.3 1.0 105.2 16.0 27.6 0.8 10.1 202.1 141.4 106.3 6.1 14.0 84.4 52.8 ANKRD62 DKFZp779B1634 ENSG00000181626 "Ankyrin repeat domain 62" A6NC57 18 12093843-12129764 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "brain: 1.1;pancreas: 1.0;testis: 1.6" "Cell type enriched" "Detected in some" 5 "Spermatocytes: 92.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059835 Enhanced Uncertain "Nucleoplasm,Nuclear bodies,Actin filaments" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Actin filaments" "HPA059835: AB_2684136" "unprognostic (2.45e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-3)" "unprognostic (9.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (6.61e-2)" "unprognostic (7.95e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-4)" "unprognostic (1.13e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-3)" "unprognostic (8.70e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.4 0.0 0.6 0.0 0.7 0.0 0.0 0.4 0.1 0.0 1.3 0.3 0.1 0.4 0.3 0.0 0.0 1.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 2.2 0.1 0.2 0.5 0.0 0.0 16.5 1.7 0.6 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.6 0.8 2.6 0.6 0.2 0.0 1.0 0.0 0.1 1.0 1.0 0.2 0.5 1.1 0.4 0.0 0.8 0.2 0.0 0.0 0.9 0.0 1.3 0.3 92.8 15.8 0.5 1.1 0.0 0.2 0.1 0.2 0.5 CIDEA CIDE-A ENSG00000176194 "Cell death inducing DFFA like effector a" O60543 18 12254361-12277595 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "adipose tissue: 221.3;breast: 108.0" "Cell type enriched" "Detected in some" 78 "Breast glandular cells: 330.6" "Cancer enhanced" "Detected in some" "breast cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "hTEC/SVTERT24-B: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "unprognostic (2.96e-2)" "unprognostic (2.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (8.93e-3)" "unprognostic (3.20e-2)" "unprognostic (7.00e-2)" "unprognostic (3.72e-2)" "unprognostic (1.91e-3)" "unprognostic (3.17e-2)" "unprognostic (7.67e-3)" "unprognostic (1.96e-1)" 221.3 3.7 2.3 0.2 3.2 0.0 108.0 2.8 5.2 3.5 1.7 1.5 0.0 0.0 0.0 4.8 0.0 1.2 1.9 2.7 1.8 0.2 0.2 0.0 0.3 2.4 2.2 0.0 0.9 0.0 0.0 0.0 2.7 0.1 0.9 0.1 4.3 0.0 1.0 9.3 2.1 0.2 2.2 0.0 1.0 0.1 2.0 0.2 0.5 4.6 0.2 1.1 5.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.8 5.2 2.7 1.8 2.4 2.2 2.7 2.2 2.0 3.0 1.9 0.0 0.0 0.7 0.5 0.1 0.1 0.3 0.0 0.2 330.6 3.8 0.6 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.3 1.0 0.0 0.2 0.3 0.0 0.0 3.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 4.2 0.6 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.3 0.7 1.0 0.0 0.3 0.5 0.0 0.8 TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 190.2;Extravillous trophoblasts: 494.3;Pancreatic endocrine cells: 221.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.3" "Group enriched" "Detected in many" 6 "B-cells: 58.7;dendritic cells: 157.3" "Cell line enhanced" "Detected in many" "TIME: 821.6" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 10.3" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes Yes 52000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA043640: AB_2678594, HPA046280: AB_2679612" "unprognostic (4.40e-2)" "unprognostic (8.28e-3)" "unprognostic (1.22e-2)" "unprognostic (5.20e-3)" "unprognostic (8.42e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-1)" "unprognostic (2.74e-2)" "unprognostic (4.95e-2)" "unprognostic (4.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (5.83e-3)" "unprognostic (1.99e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (9.69e-4)" 197.9 37.9 12.3 82.1 11.7 34.8 134.6 14.7 14.6 106.5 28.6 193.6 31.4 173.5 24.9 217.5 121.2 66.4 166.2 11.8 13.7 66.0 40.8 92.9 31.6 19.2 16.3 81.2 52.7 5.6 33.1 59.7 15.1 84.2 28.8 3.6 69.6 91.3 37.3 78.2 75.8 151.9 14.1 34.0 89.1 28.3 18.4 12.2 52.2 20.2 31.3 129.9 124.2 12.5 211.8 142.3 149.5 76.1 149.0 208.8 108.1 648.5 424.2 492.0 459.1 113.0 65.2 1.3 281.7 440.8 148.6 99.5 84.7 653.6 380.6 1.8 46.1 32.3 159.2 73.6 151.0 2.7 59.5 219.1 146.0 429.4 222.7 148.8 366.1 12.5 159.7 2.5 432.5 216.1 0.8 162.4 79.1 3.3 70.0 1.6 260.0 2.2 99.7 5.8 19.3 27.2 360.3 34.8 113.9 153.7 76.5 203.8 821.6 600.0 510.6 565.7 574.2 11.5 3.8 3.8 458.9 46.9 219.8 2.0 19.4 0.3 0.6 7.6 0.3 42.0 0.1 0.2 25.5 58.7 0.2 0.3 0.4 0.9 7.5 157.3 0.2 13.2 12.3 11.7 14.7 14.6 11.8 13.7 19.2 16.3 15.1 14.1 18.4 12.5 67.0 83.3 7.9 0.7 16.1 69.6 42.7 151.4 16.5 1.2 30.4 44.8 54.3 8.6 37.4 7.3 0.0 53.8 23.6 0.6 1.9 167.6 190.2 6.4 76.9 128.9 0.0 12.2 0.8 104.9 494.3 112.8 1.5 7.1 45.6 7.4 82.5 0.4 69.4 0.0 0.6 0.4 42.7 13.2 85.2 114.9 70.2 36.5 33.8 12.2 65.9 0.2 0.0 0.5 0.4 221.1 0.1 91.4 1.0 51.5 0.1 1.2 18.2 1.6 26.3 89.2 130.5 4.3 6.3 55.7 66.9 22.2 3.6 9.5 0.5 65.2 AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004479, HPA004480" Enhanced Supported Mitochondria NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA004479: AB_1078109, HPA004480: AB_1078108" "unprognostic (1.11e-1)" "unprognostic (7.49e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.31e-1)" "unprognostic (5.06e-3)" "unprognostic (1.61e-1)" "unprognostic (2.33e-1)" "unprognostic (5.35e-2)" "unprognostic (1.54e-2)" "unprognostic (4.05e-2)" "unprognostic (3.00e-2)" "prognostic favorable (6.05e-14)" "unprognostic (5.90e-2)" "unprognostic (9.41e-2)" "unprognostic (5.74e-3)" "unprognostic (2.22e-1)" 26.1 25.9 16.4 21.9 17.0 32.4 29.2 18.2 19.0 24.1 30.8 60.8 79.9 22.1 17.5 41.5 23.8 18.3 88.0 17.0 18.7 62.7 51.0 21.8 23.7 17.7 16.6 24.1 41.1 76.0 18.6 23.5 18.8 24.6 54.1 20.3 30.8 24.4 145.4 29.8 58.7 25.4 15.8 18.5 39.1 18.5 19.0 24.3 39.2 155.8 31.0 30.9 19.6 17.6 56.5 56.6 39.7 44.8 45.2 48.6 52.7 61.9 61.1 86.6 63.1 88.1 34.1 161.3 66.3 56.6 76.8 55.6 101.4 71.3 70.3 38.1 43.5 48.5 59.3 83.5 61.1 185.0 69.8 54.3 76.3 82.1 107.7 47.8 64.0 57.0 111.3 92.8 43.6 89.0 66.7 58.5 55.3 277.4 41.9 74.0 125.1 135.2 74.9 123.6 73.7 51.3 97.0 103.8 90.0 50.5 47.8 84.5 49.0 102.4 88.6 98.7 81.7 64.7 80.7 104.1 56.2 71.4 48.0 3.8 16.5 12.4 11.6 17.6 13.9 14.0 13.8 17.9 21.8 10.3 17.2 20.2 1.1 28.4 16.2 11.5 9.5 13.4 16.4 17.0 18.2 19.0 17.0 18.7 17.7 16.6 18.8 15.8 19.0 17.6 24.3 41.7 49.2 23.2 36.6 22.2 45.3 21.5 42.7 50.2 36.5 36.2 74.9 50.1 28.1 35.0 50.1 58.5 29.1 85.2 72.4 39.5 5.5 37.8 52.3 27.7 39.1 61.0 21.1 37.4 37.9 31.2 53.5 46.1 14.5 41.3 21.8 85.6 37.0 30.3 26.8 82.6 18.3 32.6 14.4 5.5 32.9 34.2 23.2 12.2 27.6 26.9 40.2 14.1 17.7 47.8 43.1 30.1 38.8 43.1 88.7 100.0 22.1 58.3 26.3 53.6 26.9 50.9 65.0 75.8 31.3 92.8 28.4 60.8 94.9 38.2 PRELID3A "C18orf43, FLJ31484, HFL-EDDG1, SLMO1" ENSG00000141391 "PRELI domain containing 3A" Q96N28 18 12407896-12432238 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 24.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.0;Hofbauer cells: 5.7;Horizontal cells: 8.4;Rod photoreceptor cells: 5.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "hTERT-HME1: 36.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.75e-1)" "unprognostic (1.02e-2)" "unprognostic (1.87e-2)" "prognostic unfavorable (5.89e-7)" "unprognostic (2.08e-2)" "unprognostic (3.56e-1)" "unprognostic (2.77e-2)" "unprognostic (2.10e-1)" "unprognostic (1.69e-2)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.11e-1)" "unprognostic (1.08e-11)" "unprognostic (2.63e-2)" "unprognostic (2.65e-1)" "unprognostic (1.44e-2)" "unprognostic (9.42e-2)" 6.1 4.1 10.7 2.7 12.3 7.2 5.0 11.3 14.1 7.4 17.9 6.3 1.7 7.3 5.0 3.2 8.2 4.4 3.5 10.7 9.9 2.9 1.1 4.1 3.5 15.3 10.4 7.4 7.0 2.8 9.3 3.2 14.9 5.2 3.1 10.3 2.4 11.7 1.7 4.1 4.1 5.7 9.2 3.9 3.6 2.9 11.7 2.5 4.7 3.2 2.5 4.9 4.8 24.8 8.5 4.8 5.9 9.9 5.6 9.3 4.5 10.3 4.1 5.9 3.3 5.4 3.6 14.2 3.0 9.4 8.5 4.0 12.1 7.8 3.6 7.5 9.8 6.2 9.4 9.5 8.5 3.1 3.6 8.8 7.3 8.3 36.6 11.8 5.7 0.5 15.8 7.2 3.2 7.5 0.4 16.9 6.7 0.8 5.3 0.3 14.3 11.5 2.8 1.6 27.8 12.3 9.7 5.7 13.4 3.3 6.9 4.7 4.4 20.6 13.0 13.9 14.4 3.2 2.4 23.3 5.6 4.6 6.6 4.0 0.6 2.3 0.4 0.2 0.5 0.8 0.4 0.4 0.4 0.7 0.5 0.6 1.7 0.7 0.4 0.6 0.2 0.2 10.7 12.3 11.3 14.1 10.7 9.9 15.3 10.4 14.9 9.2 11.7 24.8 1.6 3.2 0.0 0.0 0.4 0.0 1.0 0.0 0.6 14.0 2.7 2.9 0.0 0.0 0.6 1.8 2.1 0.1 0.0 0.0 0.0 0.9 0.0 0.3 2.9 1.5 0.0 0.4 0.0 0.8 0.6 1.9 1.5 0.3 0.0 4.2 0.4 0.0 5.7 8.4 0.0 1.2 0.0 0.6 0.0 0.1 1.8 1.5 0.0 0.0 0.0 3.6 0.0 0.0 0.0 1.6 0.0 4.1 1.2 2.8 0.1 0.1 0.0 5.1 0.0 1.4 3.0 0.1 1.1 0.3 0.0 0.1 0.3 2.6 0.7 0.5 SPIRE1 "KIAA1135, spir-1" ENSG00000134278 "Spire type actin nucleation factor 1" Q08AE8 18 12446512-12658134 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 151.8;Early spermatids: 167.4;Excitatory neurons: 165.2;Inhibitory neurons: 155.9;Late spermatids: 321.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 97.3;U-2197: 75.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040737, HPA040942" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA040737: AB_10960987, HPA040942: AB_10960492" "unprognostic (3.39e-1)" "unprognostic (4.77e-2)" "unprognostic (9.18e-2)" "prognostic unfavorable (2.07e-4)" "unprognostic (2.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.09e-1)" "unprognostic (1.60e-1)" "unprognostic (9.49e-2)" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (4.60e-1)" "unprognostic (3.66e-3)" "prognostic unfavorable (7.92e-4)" "unprognostic (1.41e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-1)" 7.6 17.4 22.1 3.8 22.8 1.0 9.0 22.5 27.8 8.6 6.6 7.7 1.7 7.6 5.5 7.2 5.2 7.2 20.7 23.5 18.9 10.7 5.0 10.8 2.8 20.4 20.3 8.0 5.1 17.5 6.1 6.4 20.3 8.3 3.1 14.7 8.9 8.0 20.6 8.4 3.2 8.3 19.9 4.5 5.5 33.6 25.3 3.4 13.2 19.3 4.0 9.1 5.8 26.8 19.0 8.2 17.7 19.7 19.5 17.3 0.9 20.1 20.7 19.4 18.4 0.9 4.1 8.9 22.2 26.0 32.2 4.1 24.0 18.0 24.4 13.4 11.9 5.5 16.9 10.7 40.0 3.9 13.6 12.0 33.4 33.6 97.3 22.4 26.3 3.0 14.2 0.2 29.1 25.2 1.0 5.2 7.5 6.7 20.2 0.0 21.8 19.0 23.5 25.5 25.9 10.6 21.8 17.9 45.3 7.9 5.7 11.7 32.3 32.0 9.5 75.4 24.1 6.6 0.7 0.6 25.6 2.4 8.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 22.1 22.8 22.5 27.8 23.5 18.9 20.4 20.3 20.3 19.9 25.3 26.8 10.1 25.6 43.2 151.8 0.5 3.7 9.7 8.3 1.2 60.5 15.6 12.3 28.5 7.2 13.6 12.9 8.4 0.1 2.5 0.5 21.5 8.2 167.4 5.7 25.6 10.7 3.0 0.8 165.2 4.9 0.9 13.0 2.0 7.9 15.8 11.5 5.3 4.6 14.2 26.9 155.9 3.7 0.0 17.2 5.3 321.5 5.9 12.9 17.8 30.9 2.3 15.5 0.0 93.5 91.2 11.7 0.1 10.9 1.1 23.1 0.2 1.0 8.4 13.2 19.7 20.0 15.4 17.4 17.5 2.0 2.3 0.5 2.2 16.7 0.1 16.8 PSMG2 "CLAST3, HCCA3, HsT1707, MDS003, MGC15092, PAC2, TNFSF5IP1" ENSG00000128789 "Proteasome assembly chaperone 2" Q969U7 18 12658043-12725740 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 537.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 436.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041517, HPA046741" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA041517: AB_2677530, HPA046741: AB_2679780" "unprognostic (2.28e-2)" "unprognostic (9.44e-3)" "unprognostic (9.68e-2)" "unprognostic (1.15e-1)" "unprognostic (4.40e-1)" "unprognostic (1.43e-1)" "unprognostic (4.66e-2)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "prognostic favorable (3.09e-4)" "unprognostic (5.91e-2)" "unprognostic (2.27e-1)" "unprognostic (1.73e-1)" "unprognostic (9.04e-2)" "unprognostic (1.23e-1)" "unprognostic (4.82e-2)" "unprognostic (6.75e-3)" 65.6 50.3 43.5 44.8 43.4 91.9 65.2 47.0 54.8 53.0 43.2 56.3 48.3 49.0 67.5 63.5 47.7 53.2 47.3 43.5 44.9 57.2 65.6 44.3 65.1 44.7 42.8 60.6 55.9 31.1 31.8 52.9 44.4 42.5 60.5 25.1 46.6 47.9 50.9 56.0 47.8 53.0 46.9 43.8 53.7 89.7 42.9 67.6 49.6 39.5 63.7 63.8 52.0 49.2 82.6 51.3 58.2 74.0 100.1 142.5 75.0 81.3 115.7 131.1 147.8 89.1 84.6 90.6 64.6 86.2 108.3 49.8 93.7 99.9 112.2 48.6 52.4 50.1 43.0 101.8 100.7 170.7 78.7 116.8 76.0 80.7 107.6 81.3 92.5 78.7 77.4 112.9 102.4 83.0 109.9 226.1 46.2 436.4 67.8 78.8 87.5 130.2 121.0 106.3 69.6 52.5 77.5 88.1 78.1 56.3 75.8 136.2 63.5 148.9 203.3 131.3 89.4 101.1 142.9 111.1 90.1 88.5 63.3 84.9 89.3 87.6 65.3 95.1 77.6 70.3 84.0 74.8 80.5 62.5 74.6 72.2 30.9 73.9 111.6 65.7 108.2 91.7 43.5 43.4 47.0 54.8 43.5 44.9 44.7 42.8 44.4 46.9 42.9 49.2 96.1 51.3 50.1 42.7 76.4 91.0 98.8 145.2 80.8 25.1 81.4 99.2 36.0 82.9 80.9 82.8 22.9 183.0 80.9 70.8 154.6 110.5 537.7 59.8 75.8 83.9 68.6 97.2 50.1 110.8 140.3 99.3 59.1 53.3 60.9 74.9 101.7 53.1 147.6 25.2 50.3 87.8 54.9 133.0 88.7 140.8 134.2 100.2 72.9 26.2 130.7 63.8 50.4 34.7 38.5 103.2 84.2 97.0 67.1 126.1 120.6 193.8 68.7 21.4 85.5 78.4 89.8 344.9 216.8 119.5 90.1 186.3 78.8 122.3 103.6 130.7 CEP76 "C18orf9, FLJ12542, HsT1705" ENSG00000101624 "Centrosomal protein 76" Q8TAP6 18 12661833-12702777 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 209.7;Late spermatids: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 60.5" "Region enriched" "Detected in all" 9 "cerebellum: 55.0" "Region enriched" "Detected in all" 5 "cerebellum: 16.3" HPA039395 Approved NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039395: AB_10673357" "unprognostic (3.39e-1)" "unprognostic (2.99e-2)" "unprognostic (2.26e-1)" "unprognostic (9.31e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-1)" "unprognostic (2.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.00e-4)" "unprognostic (7.88e-3)" "unprognostic (2.45e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-2)" "unprognostic (4.39e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-2)" "unprognostic (8.21e-2)" 3.0 3.4 2.5 2.6 2.5 6.2 3.8 7.7 3.3 3.4 2.6 2.9 2.7 3.3 5.1 5.3 2.7 2.6 2.7 2.3 2.5 3.1 4.8 2.7 3.8 2.3 2.4 3.2 2.3 2.5 2.2 3.4 2.5 2.8 3.9 4.5 2.9 2.8 3.2 4.0 3.1 3.3 2.3 2.5 2.8 8.2 2.6 7.9 3.7 3.5 4.7 3.2 2.8 2.6 7.3 7.2 12.1 5.9 7.1 3.8 11.7 8.4 9.4 16.1 12.5 16.6 8.5 9.7 7.3 5.5 9.4 5.6 12.1 5.3 13.7 6.1 9.8 8.5 8.0 14.1 5.3 20.0 9.5 3.0 5.3 9.5 6.2 4.5 8.5 13.5 14.5 14.3 10.4 5.5 17.5 13.9 8.7 60.5 4.7 12.2 10.5 10.4 8.4 7.1 9.2 8.0 10.5 6.7 6.9 7.9 4.8 11.0 8.0 10.8 21.9 10.6 10.0 8.0 14.8 11.5 5.4 9.7 7.2 0.4 2.3 2.1 2.6 4.4 3.5 1.8 2.9 3.2 2.1 2.3 2.9 3.4 0.7 3.7 1.7 1.2 3.5 2.2 2.5 2.5 7.7 3.3 2.3 2.5 2.3 2.4 2.5 2.3 2.6 2.6 4.3 6.4 5.9 7.5 7.2 9.7 3.9 3.0 5.2 6.3 4.1 4.6 1.8 1.5 5.4 0.0 12.5 5.9 6.7 3.7 1.9 3.0 209.7 5.5 5.8 5.2 6.0 13.9 16.9 2.5 7.5 4.0 2.0 4.6 5.7 14.0 4.2 4.8 4.1 3.3 16.7 5.5 4.1 3.5 4.1 57.8 3.7 3.4 7.2 3.7 2.5 2.9 6.2 7.5 7.9 3.8 0.6 4.5 10.3 5.1 7.8 2.5 3.5 8.0 6.6 7.1 3.7 27.7 22.1 12.4 8.2 6.2 6.4 11.5 4.8 5.7 PTPN2 "PTPT, TC-PTP, TCELLPTP, TCPTP" ENSG00000175354 "Protein tyrosine phosphatase non-receptor type 2" P17706 18 12785478-12929643 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 99.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015004, HPA046176" Enhanced Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA015004: AB_2669131, HPA046176: AB_2679569" "unprognostic (5.83e-3)" "unprognostic (8.50e-2)" "unprognostic (5.85e-2)" "unprognostic (7.21e-3)" "unprognostic (8.94e-3)" "unprognostic (2.31e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (2.37e-3)" "prognostic favorable (1.37e-4)" "unprognostic (1.06e-2)" "unprognostic (1.75e-2)" "prognostic unfavorable (1.20e-8)" "unprognostic (3.19e-1)" "unprognostic (6.84e-3)" "unprognostic (2.17e-1)" "unprognostic (4.61e-3)" 23.4 15.2 10.0 32.8 10.8 57.2 23.7 21.0 17.1 19.9 15.6 22.2 18.9 16.0 20.4 20.0 17.4 22.4 14.7 11.0 10.4 17.3 25.8 26.3 44.4 12.3 10.4 26.8 33.1 14.1 18.3 19.5 11.8 17.6 24.1 20.2 29.4 13.5 16.7 21.0 19.5 16.9 10.7 28.5 18.0 13.6 10.0 99.8 17.5 11.9 43.5 37.2 19.9 14.3 34.8 20.7 23.7 7.9 26.5 47.4 23.0 22.7 50.2 47.5 42.2 45.4 48.8 54.3 37.2 23.6 53.2 20.4 39.0 62.2 62.1 21.2 23.5 38.4 17.7 47.6 36.4 91.1 35.1 40.2 57.6 43.3 85.1 29.2 24.6 58.1 37.9 71.6 38.6 39.9 91.3 74.5 28.5 141.7 24.0 30.4 37.3 61.9 40.2 54.6 42.3 22.0 46.0 26.7 41.8 25.1 22.4 51.5 18.8 59.8 58.0 45.1 49.8 22.6 24.5 77.8 28.3 49.3 25.7 23.7 52.6 39.2 37.0 47.7 50.4 54.4 43.7 41.4 62.5 39.5 31.6 34.9 19.0 64.1 46.7 53.0 57.3 40.7 10.0 10.8 21.0 17.1 11.0 10.4 12.3 10.4 11.8 10.7 10.0 14.3 25.8 35.3 77.0 38.5 82.4 59.9 106.0 88.0 61.5 44.1 37.0 50.5 15.0 47.1 84.4 14.7 104.3 54.1 130.4 32.2 13.7 55.1 24.3 51.0 44.8 32.0 32.3 40.8 81.1 68.8 52.5 38.1 24.5 78.7 56.4 53.1 20.3 27.9 51.3 15.2 60.5 35.0 69.2 99.2 92.5 23.2 29.2 93.4 23.2 44.0 137.0 17.6 128.8 22.6 55.0 40.0 45.1 25.6 120.2 126.4 29.9 23.1 55.4 84.5 19.7 35.4 33.8 23.3 61.3 40.0 50.2 81.1 84.2 65.2 39.5 152.4 SEH1L "SEC13L, Seh1, SEH1A, SEH1B" ENSG00000085415 "SEH1 like nucleoporin" Q96EE3 18 12947133-12987536 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Chromosome partition, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039964 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA039964: AB_10795241" "unprognostic (5.14e-2)" "unprognostic (1.23e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (7.97e-2)" "unprognostic (1.87e-2)" "unprognostic (1.13e-3)" "unprognostic (7.14e-2)" "unprognostic (1.93e-2)" "unprognostic (1.45e-3)" "unprognostic (7.12e-2)" "unprognostic (8.06e-2)" "unprognostic (3.81e-3)" "unprognostic (5.91e-2)" "unprognostic (3.01e-1)" "unprognostic (2.67e-1)" "unprognostic (7.05e-2)" 17.4 12.0 15.8 16.5 17.0 12.8 14.5 14.8 22.9 12.5 12.5 15.0 11.6 13.7 12.2 19.7 12.1 9.8 15.6 19.8 18.3 14.9 22.4 12.3 19.8 12.2 12.1 12.1 15.1 10.7 14.2 12.6 12.7 11.1 13.9 6.5 11.9 9.1 37.3 15.8 12.0 13.4 13.4 13.2 12.0 15.0 16.6 23.8 12.5 26.9 21.5 19.2 13.2 17.8 53.6 40.6 30.9 49.2 21.2 31.5 45.1 45.5 46.3 52.3 59.8 104.7 27.5 114.8 54.0 53.1 46.8 26.6 72.8 52.0 67.5 31.9 46.8 71.6 38.4 62.3 47.7 197.0 45.4 22.5 40.1 60.6 88.8 21.8 27.7 51.6 98.1 41.5 42.9 57.9 106.3 84.4 39.2 215.5 41.9 70.6 71.8 74.6 40.6 53.4 59.8 35.7 58.2 43.7 47.9 22.3 27.3 64.7 22.4 53.5 123.6 81.4 80.7 30.6 48.1 122.1 35.1 70.1 35.0 4.1 23.5 5.6 14.0 31.6 18.5 23.7 16.3 17.0 37.8 23.9 20.9 18.0 2.6 23.6 26.4 20.6 12.2 22.6 15.8 17.0 14.8 22.9 19.8 18.3 12.2 12.1 12.7 13.4 16.6 17.8 13.1 6.4 20.2 8.5 26.5 54.7 47.0 24.6 40.9 8.0 16.3 12.8 14.0 14.3 18.3 12.9 12.5 23.6 16.1 12.9 9.8 15.0 9.2 18.5 19.2 19.3 19.2 26.1 15.3 13.3 31.8 17.9 15.8 27.6 7.6 17.8 13.2 21.6 21.3 3.3 10.1 20.3 14.2 13.2 20.4 11.4 9.3 19.7 16.0 12.2 16.9 5.8 7.2 6.0 13.3 16.0 15.3 10.9 23.9 46.7 11.5 16.5 8.5 10.1 13.1 26.8 22.3 16.9 14.0 41.6 59.8 23.7 16.0 19.6 24.9 43.0 CEP192 "FLJ10352, KIAA1569, PPP1R62" ENSG00000101639 "Centrosomal protein 192" Q8TEP8 18 12991362-13125052 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 67.6;Excitatory neurons: 94.4;Inhibitory neurons: 91.3;Oligodendrocyte precursor cells: 76.9;Oligodendrocytes: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039392, HPA040503" Uncertain Supported Centrosome,Cytosol Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Centrosome, Cytosol" "HPA039392: AB_10697549, HPA040503: AB_10670919" "unprognostic (6.94e-2)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.89e-2)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (1.13e-3)" "unprognostic (6.87e-3)" "unprognostic (5.83e-3)" "unprognostic (2.20e-2)" "unprognostic (9.00e-2)" "unprognostic (6.61e-2)" "unprognostic (1.28e-1)" "unprognostic (7.89e-2)" "unprognostic (2.39e-1)" "unprognostic (4.54e-2)" "unprognostic (1.66e-3)" 2.9 2.2 5.0 4.6 7.6 10.8 4.9 9.8 5.2 4.7 0.0 4.5 4.0 6.4 3.9 3.7 4.9 5.7 3.6 4.1 2.4 2.8 2.9 4.4 6.9 4.1 4.7 9.9 4.6 4.7 2.5 4.6 3.6 4.0 5.4 6.8 4.1 3.5 1.8 3.5 4.7 4.6 3.4 5.2 4.7 9.3 5.0 11.6 5.5 3.9 5.6 4.1 2.5 9.7 13.5 7.2 19.1 10.1 8.1 12.6 6.1 9.2 12.1 14.3 15.1 9.9 5.8 15.2 6.1 9.4 10.4 6.4 16.7 8.8 16.8 6.0 6.0 13.8 11.3 5.2 4.3 22.2 10.2 8.8 3.2 12.0 10.9 8.2 11.9 10.7 19.3 9.9 11.3 6.8 19.2 9.6 6.1 24.9 4.4 16.3 14.9 7.9 4.9 13.6 13.9 7.8 14.7 7.2 4.4 9.0 5.8 11.3 12.1 11.2 26.2 12.9 12.8 6.6 10.1 17.0 7.2 9.9 11.0 0.4 0.6 0.5 0.9 0.4 0.7 0.5 0.6 0.6 0.3 1.3 0.6 1.0 0.6 0.2 1.7 0.5 0.5 0.3 5.0 7.6 9.8 5.2 4.1 2.4 4.1 4.7 3.6 3.4 5.0 9.7 13.3 9.6 12.8 67.6 11.4 1.9 3.9 4.3 5.2 13.1 6.4 5.8 28.7 4.3 9.3 7.3 22.9 5.3 13.7 7.6 0.0 4.7 23.3 11.0 11.8 8.5 0.0 18.7 94.4 3.6 3.3 10.5 15.8 12.1 2.5 40.9 8.2 6.5 4.6 11.8 91.3 8.7 4.1 10.1 3.9 14.2 10.2 10.1 1.8 62.8 15.3 6.5 14.4 76.9 90.6 4.8 5.7 13.9 15.0 5.5 4.5 1.2 8.0 17.8 26.3 11.3 8.1 33.5 24.0 8.5 3.1 1.9 12.3 60.6 8.0 7.6 LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;lymphoid tissue: 49.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 338.9;Inhibitory neurons: 308.5;Late spermatids: 231.5;Microglial cells: 429.1;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 35.3;JURKAT: 37.4;MOLT-4: 131.3;REH: 31.6;U-698: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" 6.5 4.3 13.9 7.3 38.0 9.7 6.3 34.6 25.9 7.8 37.4 5.8 6.1 12.4 0.9 3.9 11.3 4.6 16.6 10.7 16.4 4.0 10.3 4.6 6.5 46.1 33.2 2.3 3.3 2.9 6.9 6.2 38.6 8.6 2.1 7.0 3.0 5.3 15.4 4.2 7.2 5.7 27.3 5.6 5.0 9.2 48.2 49.3 4.4 9.5 3.8 5.3 5.3 39.6 0.2 0.3 1.4 0.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.7 1.6 0.8 0.4 0.0 0.0 0.0 17.1 1.7 35.3 7.0 1.2 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.4 37.4 0.4 0.7 0.0 2.6 131.3 1.1 2.9 0.3 8.9 31.6 0.1 1.2 0.0 1.1 2.4 3.9 0.5 2.2 0.0 1.9 3.8 4.7 2.4 1.3 11.5 0.2 1.9 5.6 0.4 26.1 0.0 6.9 6.4 12.8 7.0 2.1 6.5 7.7 5.7 5.2 5.8 5.6 3.9 4.4 8.2 7.6 12.1 9.1 8.5 5.9 3.4 4.5 13.9 38.0 34.6 25.9 10.7 16.4 46.1 33.2 38.6 27.3 48.2 39.6 19.4 3.2 4.7 143.3 79.2 10.5 2.7 0.8 0.0 5.4 26.0 16.9 18.4 0.0 5.0 1.8 70.9 0.6 21.0 6.8 1.9 5.1 135.2 16.3 22.0 16.6 58.7 7.6 338.9 3.6 0.7 16.5 13.3 7.8 23.5 7.6 25.0 24.4 21.1 0.0 308.5 9.1 2.0 27.4 160.5 231.5 11.1 56.2 14.2 429.1 13.6 4.7 3.1 318.7 284.9 0.7 2.6 24.5 11.7 13.5 15.6 2.3 13.7 18.7 6.6 2.3 9.7 5.4 4.9 0.4 7.7 1.6 66.0 0.2 8.8 3.2 FAM210A "C18orf19, HsT2329, MGC24180" ENSG00000177150 "Family with sequence similarity 210 member A" Q96ND0 18 13663347-13726663 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 33.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014324, HPA051564" Uncertain Approved "Nucleoplasm,Golgi apparatus,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Golgi apparatus, Mitochondria" "HPA014324: AB_2668972, HPA051564: AB_2681536" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (5.78e-2)" "unprognostic (9.18e-3)" "unprognostic (4.13e-2)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.23e-3)" "unprognostic (1.11e-2)" "unprognostic (2.26e-1)" "unprognostic (5.53e-3)" "unprognostic (6.79e-3)" "unprognostic (2.98e-2)" "unprognostic (3.27e-3)" "unprognostic (7.67e-2)" "unprognostic (2.86e-1)" "unprognostic (1.78e-1)" "unprognostic (4.82e-2)" 6.1 4.7 4.7 5.5 4.5 3.5 4.8 5.8 7.1 4.2 8.0 6.9 9.3 3.9 2.9 8.8 4.2 4.0 21.8 4.6 5.3 9.4 13.2 4.0 6.4 5.2 7.0 5.6 3.3 6.4 2.6 7.5 5.6 4.4 6.4 11.5 5.1 4.6 25.5 3.3 6.2 6.2 5.1 3.7 4.7 8.4 6.3 5.3 6.3 33.1 7.3 6.3 5.0 5.7 24.6 13.6 9.4 8.8 10.9 11.2 13.6 16.5 15.3 18.2 21.1 18.4 11.6 24.9 20.2 11.8 33.6 11.5 18.2 20.6 29.5 17.4 8.4 17.7 9.7 13.0 12.9 30.3 15.9 9.7 15.9 17.5 61.6 12.7 11.9 14.8 24.2 13.4 21.2 16.8 18.7 19.5 10.6 47.7 13.5 15.2 22.3 29.1 15.1 15.3 6.0 10.1 14.5 21.1 40.0 13.4 10.8 14.2 13.2 46.4 45.7 29.1 20.6 15.1 20.1 28.8 24.6 15.6 18.9 3.5 5.3 3.3 6.2 8.0 6.8 5.7 5.2 5.4 6.4 6.3 6.4 6.2 0.8 6.0 4.2 4.0 5.4 3.8 4.7 4.5 5.8 7.1 4.6 5.3 5.2 7.0 5.6 5.1 6.3 5.7 14.9 9.6 8.3 13.7 29.8 55.3 14.8 28.3 12.5 63.2 11.0 11.2 66.4 12.8 14.6 7.3 20.9 20.6 11.6 9.1 21.5 18.6 20.5 16.7 21.6 18.3 11.4 5.9 18.0 8.8 39.0 17.4 10.2 32.7 7.0 36.7 6.8 20.7 20.0 30.3 23.5 10.0 10.2 9.5 43.4 6.1 9.3 26.5 8.8 15.0 11.4 19.0 15.5 18.6 24.8 12.6 4.1 10.1 14.2 19.9 12.1 29.8 5.0 29.9 6.6 16.3 15.4 31.4 32.3 20.6 57.3 25.7 16.8 45.6 20.5 14.8 RNMT RG7MT1 ENSG00000101654 "RNA guanine-7 methyltransferase" O43148 18 13726660-13764556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039409 Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA039409: AB_10795289" "unprognostic (3.02e-1)" "unprognostic (1.07e-2)" "unprognostic (3.48e-1)" "unprognostic (1.71e-3)" "unprognostic (3.57e-1)" "unprognostic (3.04e-1)" "unprognostic (6.17e-3)" "unprognostic (1.43e-1)" "unprognostic (3.76e-2)" "unprognostic (1.42e-3)" "unprognostic (9.45e-2)" "unprognostic (9.15e-2)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (2.77e-2)" "unprognostic (1.78e-1)" 10.9 9.6 11.8 12.6 12.1 43.3 15.3 12.2 13.0 11.3 17.2 11.6 8.5 14.0 11.5 11.3 11.2 9.0 20.3 12.1 14.2 11.6 11.2 9.5 14.4 13.6 15.2 17.2 12.1 13.0 13.9 15.2 14.8 11.6 10.4 27.4 12.1 10.5 18.4 14.2 10.5 12.5 10.9 12.1 10.6 16.7 11.7 14.9 17.5 15.6 15.2 11.4 10.7 12.6 24.9 14.4 27.4 20.9 20.0 25.1 19.2 19.9 24.7 20.3 27.4 17.3 11.7 27.7 23.9 20.6 31.6 9.8 32.7 28.6 34.0 15.4 17.6 21.0 14.8 16.4 21.9 54.9 17.1 19.4 30.5 21.4 59.9 26.6 15.9 31.1 31.8 26.9 23.3 15.4 35.2 19.7 21.0 50.1 11.2 22.7 29.0 37.9 18.6 19.2 21.1 31.7 22.5 16.4 38.1 27.8 14.3 22.6 16.5 40.6 56.8 33.3 21.5 53.8 63.6 56.9 29.9 20.8 20.6 45.1 17.6 12.8 16.7 14.6 13.6 23.9 15.8 14.2 11.8 25.7 20.5 16.2 9.8 14.1 17.3 29.5 19.0 5.6 11.8 12.1 12.2 13.0 12.1 14.2 13.6 15.2 14.8 10.9 11.7 12.6 62.5 73.7 29.9 48.6 148.5 70.4 67.3 97.9 75.1 115.6 50.7 56.1 56.5 35.8 56.5 46.0 123.0 66.3 143.4 46.5 68.4 51.0 75.4 85.2 88.3 43.7 74.8 37.4 75.3 48.0 59.2 71.6 66.3 113.9 34.9 85.6 40.7 38.5 39.8 106.0 83.9 56.3 85.5 59.4 63.6 21.1 72.7 78.8 49.8 45.0 68.0 51.0 60.8 56.8 78.9 56.1 47.0 60.9 99.7 72.3 49.0 64.8 48.0 148.3 39.5 85.6 60.0 111.4 115.1 50.7 68.3 126.4 113.1 48.8 50.0 50.3 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MC2R ACTHR ENSG00000185231 "Melanocortin 2 receptor" Q01718 18 13882044-13915707 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "adrenal gland: 57.9" "Cell type enhanced" "Detected in single" "Late spermatids: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079148 Enhanced NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 31: Spermatids - Spermatogenesis" "HPA079148: " "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.85e-2)" 0.0 57.9 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ZNF519 "FLJ36809, HsT2362" ENSG00000175322 "Zinc finger protein 519" Q8TB69 18 14057457-14132490 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.3;Inhibitory neurons: 64.3;Oligodendrocyte precursor cells: 30.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 5.5;SCLC-21H: 6.6" HPA028982 Uncertain Approved Nucleoli NA NA "Cluster 72: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA028982: AB_10610705" "unprognostic (1.85e-2)" "unprognostic (4.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.90e-1)" "unprognostic (2.53e-2)" "unprognostic (6.70e-2)" "unprognostic (3.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-5)" "unprognostic (1.40e-2)" "unprognostic (1.58e-1)" "unprognostic (2.38e-1)" "unprognostic (3.65e-4)" 0.9 0.5 0.3 0.3 0.3 0.3 0.9 1.3 1.0 2.4 0.0 2.4 0.1 1.9 0.3 1.7 1.5 0.4 0.8 0.3 0.2 0.3 0.4 0.5 0.6 0.2 0.2 2.0 0.6 0.2 0.8 0.2 0.3 1.2 0.5 0.4 0.8 0.4 0.4 0.9 1.0 0.7 0.2 0.9 0.7 0.8 0.2 0.6 0.9 0.3 0.4 1.6 1.7 0.4 0.6 0.0 2.3 2.2 0.0 0.5 0.9 0.4 0.3 1.7 1.6 0.7 0.6 1.2 0.8 0.2 0.5 0.6 2.3 0.3 2.5 1.0 1.4 2.7 1.3 0.4 0.0 5.5 0.8 0.1 0.6 1.2 0.3 0.3 0.2 1.9 0.9 1.8 0.7 0.3 3.7 0.8 0.9 1.2 0.7 3.3 2.9 1.6 0.3 0.4 6.6 1.2 1.2 0.1 0.8 1.8 0.4 0.8 0.2 2.7 2.5 1.1 0.9 0.3 0.6 1.3 0.7 1.8 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.3 1.3 1.0 0.3 0.2 0.2 0.2 0.3 0.2 0.2 0.4 4.6 6.4 9.5 17.6 7.6 2.0 2.4 2.5 11.4 15.0 2.8 3.8 4.9 1.5 1.3 0.0 2.1 3.2 3.3 0.6 1.9 2.5 1.1 0.6 11.2 3.2 1.2 8.0 83.3 2.0 4.2 7.6 3.1 1.1 3.8 18.2 2.9 0.7 1.7 3.3 64.3 1.9 4.1 3.1 1.9 1.8 6.5 2.3 1.8 23.4 1.6 5.9 6.2 30.2 15.9 1.0 0.4 9.1 6.0 1.2 0.3 0.7 2.0 7.4 0.0 8.4 4.2 10.7 12.2 18.3 1.3 0.8 6.4 3.6 2.4 1.4 POTEC "A26B2, CT104.6, DKFZp686J0529, POTE-18, POTE18" ENSG00000183206 "POTE ankyrin domain family member C" B2RU33 18 14507339-14543585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 2.5" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 40.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "unprognostic (9.88e-2)" "unprognostic (8.05e-2)" "unprognostic (1.64e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 40.1 4.9 0.0 0.0 0.3 0.0 0.0 0.1 0.1 ANKRD30B NY-BR-1.1 ENSG00000180777 "Ankyrin repeat domain 30B" Q9BXX2 18 14728272-14854038 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 8.2" "Group enriched" "Detected in some" 8 "Early spermatids: 13.1;Excitatory neurons: 32.6;Inhibitory neurons: 39.3;Late spermatids: 13.9;Spermatocytes: 23.7" "Cancer enriched" "Detected in single" 5 "breast cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 63.1" "HPA060455, HPA071849" Uncertain Uncertain Nucleoli NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "HPA060455: AB_2684282, HPA071849: " "unprognostic (1.53e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" "unprognostic (1.65e-1)" "unprognostic (1.86e-1)" "unprognostic (9.74e-2)" "unprognostic (2.84e-1)" "unprognostic (1.55e-9)" "unprognostic (1.38e-2)" "unprognostic (1.53e-1)" "unprognostic (7.98e-2)" 0.1 0.1 0.2 0.0 0.4 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 8.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 13.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 1.7 0.0 1.1 4.4 0.3 63.1 0.0 6.7 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.6 0.4 0.4 0.4 0.1 0.1 0.2 0.1 0.5 0.0 0.0 0.0 1.6 0.1 0.0 0.4 0.0 0.0 0.0 2.8 1.0 1.9 0.0 0.0 0.0 0.0 0.5 0.0 0.5 1.9 0.0 13.1 0.7 0.1 0.2 1.8 0.0 32.6 0.0 0.4 0.1 0.0 1.8 0.0 0.1 0.0 0.1 0.1 0.0 39.3 1.6 0.0 0.3 0.0 13.9 0.9 0.2 0.0 1.0 0.0 0.0 0.0 2.5 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.1 23.7 1.7 0.0 0.3 0.5 0.1 0.0 1.1 0.3 ROCK1 p160ROCK ENSG00000067900 "Rho associated coiled-coil containing protein kinase 1" Q13464 18 20946906-21111813 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 406.2;Late spermatids: 505.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004562, HPA007567, HPA045639" Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB004562: AB_628223, HPA007567: AB_1856393, HPA045639: AB_2679401" "unprognostic (7.86e-2)" "unprognostic (2.86e-2)" "unprognostic (1.22e-1)" "unprognostic (6.63e-2)" "unprognostic (9.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.74e-2)" "unprognostic (1.00e-1)" "unprognostic (1.63e-1)" "unprognostic (8.89e-3)" "prognostic unfavorable (9.93e-4)" "unprognostic (3.85e-2)" "unprognostic (8.93e-3)" "unprognostic (3.04e-2)" "unprognostic (5.47e-2)" "unprognostic (3.19e-1)" "unprognostic (1.28e-1)" 8.0 4.2 3.8 5.7 4.8 18.2 6.0 4.4 3.9 5.3 4.6 5.0 3.6 5.9 4.6 4.2 6.3 4.2 5.5 2.8 3.5 4.4 4.8 7.6 5.5 5.4 4.0 5.4 5.1 2.9 2.9 4.4 4.9 4.4 3.2 4.8 4.4 3.4 2.6 3.7 5.2 3.2 4.4 6.2 5.8 2.6 4.5 5.5 4.5 1.9 4.2 6.6 5.4 5.3 6.5 3.9 3.9 3.8 7.2 7.7 6.3 8.9 4.3 3.9 4.2 6.6 2.7 8.0 6.2 10.5 2.1 5.2 3.6 5.2 7.8 11.4 4.1 6.4 7.3 2.9 3.6 17.9 9.6 5.6 4.6 5.8 4.7 3.2 6.0 3.1 3.7 7.9 4.6 4.1 8.5 3.8 3.2 4.3 6.6 11.9 4.5 3.1 3.7 5.9 4.5 3.5 7.1 4.6 3.6 3.4 4.6 6.7 9.9 7.7 6.4 7.1 7.2 10.7 5.3 9.0 5.8 7.5 4.8 3.0 5.0 6.8 5.0 3.2 4.0 3.9 3.6 3.8 4.2 5.0 3.5 3.5 18.0 2.8 4.0 5.5 3.6 2.5 3.8 4.8 4.4 3.9 2.8 3.5 5.4 4.0 4.9 4.4 4.5 5.3 98.2 96.1 88.7 64.6 112.6 46.3 60.4 30.7 43.9 100.4 32.2 35.6 138.6 28.6 61.4 33.1 131.3 57.5 136.9 36.6 15.6 62.5 406.2 64.8 86.9 94.4 99.0 47.9 81.3 38.0 64.9 78.4 62.7 73.8 72.7 68.5 60.0 47.4 60.3 60.6 74.2 45.8 40.7 135.3 126.7 505.0 97.6 166.2 65.8 106.8 137.1 52.3 204.9 87.0 140.0 70.9 62.8 138.8 83.2 63.2 32.3 21.0 44.6 128.6 170.9 81.4 197.6 107.4 80.9 38.7 36.7 43.0 127.4 70.5 38.9 73.3 GREB1L "C18orf6, FLJ13687, KIAA1772" ENSG00000141449 "GREB1 like retinoic acid receptor coactivator" Q9C091 18 21242242-21525417 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 9.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 95.2;Inhibitory neurons: 39.2;Leydig cells: 46.0;Oligodendrocytes: 252.5" "Cancer enhanced" "Detected in some" "breast cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 50.7;BEWO: 100.9;CACO-2: 45.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA041647, HPA044218" Uncertain Approved Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA041647: AB_2677597, HPA044218: AB_2678859" "unprognostic (1.88e-3)" "unprognostic (9.01e-4)" "unprognostic (2.92e-1)" "unprognostic (2.45e-1)" "unprognostic (5.03e-2)" "unprognostic (3.67e-3)" "unprognostic (3.65e-1)" "unprognostic (1.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.97e-1)" "unprognostic (4.32e-3)" "unprognostic (2.87e-2)" "unprognostic (3.30e-8)" "unprognostic (4.72e-3)" "unprognostic (1.89e-1)" "unprognostic (8.80e-2)" "unprognostic (1.35e-1)" 2.6 1.4 5.5 0.1 4.3 0.2 3.3 3.5 3.6 1.2 0.0 0.6 0.1 2.6 2.8 0.2 4.4 0.1 5.3 2.6 8.1 0.4 1.8 0.2 0.1 4.0 4.7 3.7 0.1 0.3 1.2 2.1 4.1 1.6 0.1 3.1 0.5 2.9 9.2 1.3 0.5 0.8 1.7 0.0 0.6 6.2 6.4 0.0 3.8 6.8 0.0 0.1 0.7 4.4 0.0 0.9 50.7 0.0 11.4 0.0 100.9 2.4 2.4 4.3 3.8 45.7 3.7 0.1 5.1 7.6 0.1 9.7 19.4 2.4 7.5 0.7 9.3 0.0 13.4 0.4 0.3 0.0 0.0 0.0 0.7 0.1 9.3 0.5 0.0 1.4 0.0 0.3 10.5 3.5 0.2 0.2 4.9 0.4 6.0 0.2 0.0 2.0 4.8 8.7 3.2 0.0 0.1 1.6 0.2 13.2 2.7 0.2 20.9 0.5 2.9 4.9 0.0 0.1 0.7 0.0 2.2 0.0 0.4 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.5 4.3 3.5 3.6 2.6 8.1 4.0 4.7 4.1 1.7 6.4 4.4 0.4 0.0 0.5 0.7 0.4 0.1 0.1 1.0 0.0 32.3 3.1 1.1 13.4 0.0 1.1 3.7 2.1 3.2 1.8 0.1 0.0 0.2 8.3 2.2 3.4 0.5 0.0 0.0 23.1 0.4 13.2 6.2 0.0 7.0 0.0 95.2 0.0 3.1 0.5 0.0 39.2 0.2 0.0 0.0 1.1 17.9 46.0 0.3 1.8 2.8 0.1 0.8 2.1 8.0 252.5 2.8 0.0 35.7 0.0 0.6 0.3 0.0 2.3 1.6 6.6 2.8 2.3 4.3 5.6 0.0 0.9 1.5 0.3 10.5 1.5 0.2 ESCO1 "EFO1, ESO1, KIAA1911" ENSG00000141446 "Establishment of sister chromatid cohesion N-acetyltransferase 1" Q5FWF5 18 21529284-21600884 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 119.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042497 Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "HPA042497: AB_10794278" "unprognostic (8.12e-2)" "unprognostic (2.90e-2)" "unprognostic (1.91e-1)" "unprognostic (2.50e-1)" "unprognostic (6.26e-2)" "unprognostic (3.43e-3)" "unprognostic (1.38e-2)" "unprognostic (1.25e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-3)" "unprognostic (1.72e-3)" "unprognostic (6.80e-3)" "unprognostic (9.29e-2)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.72e-2)" 6.0 5.3 5.8 6.1 6.4 16.3 10.4 10.0 8.8 8.0 5.3 6.7 6.3 6.8 10.1 7.5 5.6 5.2 5.7 5.4 7.3 8.0 9.9 5.3 10.1 6.1 6.2 7.4 7.2 10.1 9.0 8.7 6.5 7.2 5.9 7.8 8.0 6.6 10.3 7.8 7.0 4.8 5.9 8.3 6.9 20.2 6.3 11.1 7.3 5.3 9.9 6.9 7.2 7.0 9.3 4.3 9.3 4.7 8.3 8.8 9.6 5.6 10.7 7.9 11.1 8.8 6.3 16.3 12.5 7.1 8.7 13.3 11.6 7.9 10.9 17.1 7.8 12.7 6.1 14.9 13.5 21.3 12.3 7.4 16.6 6.1 15.9 10.4 10.9 11.9 17.7 16.4 10.9 10.7 15.9 22.4 19.3 17.7 9.9 10.2 11.9 18.3 15.7 13.9 14.4 10.3 10.5 13.2 24.3 14.6 9.7 14.4 6.1 10.1 10.2 7.4 7.0 38.8 24.0 18.8 10.0 12.2 10.1 4.9 0.5 3.9 3.3 1.1 2.8 2.2 2.7 3.1 1.1 1.9 2.6 3.3 3.2 2.2 0.9 0.8 3.1 1.0 5.8 6.4 10.0 8.8 5.4 7.3 6.1 6.2 6.5 5.9 6.3 7.0 29.1 12.8 29.5 29.0 35.5 10.7 21.0 24.4 17.1 43.1 22.6 17.4 36.2 10.0 24.2 11.0 20.9 26.0 47.0 15.8 19.6 26.2 14.4 28.6 23.9 18.5 11.4 13.7 48.8 13.4 16.2 20.1 27.5 36.7 29.2 24.4 16.8 7.6 13.7 30.3 55.2 19.4 24.4 9.5 12.4 9.2 21.1 21.3 16.0 31.9 24.1 17.0 46.4 35.7 50.1 18.8 23.6 22.6 31.6 23.5 19.9 15.7 19.7 35.5 26.3 23.1 20.4 119.1 93.6 15.7 12.5 37.6 38.4 37.4 14.1 27.3 SNRPD1 "HsT2456, Sm-D1, SNRPD" ENSG00000167088 "Small nuclear ribonucleoprotein D1 polypeptide" P62314 18 21612314-21633524 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040516 Supported NA NA 480000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "HPA040516: AB_10673236" "unprognostic (1.83e-2)" "unprognostic (1.81e-1)" "unprognostic (7.85e-2)" "unprognostic (7.52e-2)" "unprognostic (2.18e-1)" "unprognostic (7.61e-2)" "prognostic unfavorable (1.82e-5)" "unprognostic (5.59e-2)" "unprognostic (2.15e-3)" "prognostic favorable (7.90e-6)" "unprognostic (1.87e-2)" "unprognostic (7.39e-2)" "unprognostic (3.87e-3)" "unprognostic (3.33e-2)" "unprognostic (2.06e-1)" "unprognostic (7.36e-2)" "unprognostic (3.83e-1)" 45.9 35.7 33.1 54.5 32.6 94.6 39.0 34.4 51.8 37.1 31.0 48.8 42.2 37.3 26.4 67.0 33.6 23.0 33.0 32.6 34.0 52.3 37.7 33.1 72.6 32.6 34.0 42.0 29.9 23.5 41.9 36.5 33.5 33.1 44.2 33.0 35.0 17.8 48.7 39.6 44.9 28.4 32.8 43.7 36.6 45.0 32.8 79.3 28.9 24.8 71.6 47.3 41.4 33.7 246.1 123.1 377.9 184.5 59.1 49.4 174.4 264.5 85.4 176.9 170.4 234.4 125.5 328.0 214.6 102.7 245.2 231.2 246.0 167.7 191.3 210.4 201.4 276.3 193.1 284.2 78.5 673.4 232.5 52.9 92.1 173.1 156.1 122.0 96.8 327.9 286.5 178.5 120.4 179.7 436.3 470.2 297.7 468.0 214.2 345.1 275.7 351.0 129.9 176.2 235.7 244.4 219.0 165.9 207.3 167.0 120.5 390.7 155.0 179.0 354.4 154.6 455.6 319.8 317.6 671.2 130.4 409.8 203.3 50.1 129.4 48.5 122.5 162.0 134.4 204.4 154.0 152.1 221.4 194.6 160.7 141.6 10.8 137.0 189.7 224.2 193.3 147.3 33.1 32.6 34.4 51.8 32.6 34.0 32.6 34.0 33.5 32.8 32.8 33.7 105.6 80.1 76.3 5.2 123.2 202.5 227.3 343.6 109.8 58.4 116.4 157.6 55.4 111.5 200.4 99.3 12.5 423.3 101.8 101.8 215.2 210.8 15.6 119.2 136.9 138.4 122.8 229.5 12.1 194.3 544.1 132.0 86.2 109.4 100.8 158.7 99.9 113.2 242.9 47.1 12.5 192.1 215.7 106.3 152.5 26.3 108.7 96.9 113.8 6.5 163.6 102.6 117.4 10.1 11.8 236.3 113.2 88.8 122.6 343.1 87.3 214.8 153.4 50.0 98.6 149.0 183.0 282.8 265.2 177.2 221.9 261.9 112.5 161.1 229.8 233.9 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 121.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 8.1 6.3 9.1 6.0 9.1 4.9 11.2 9.2 8.5 11.0 8.0 7.1 5.1 13.0 9.5 8.0 7.1 8.6 6.0 8.4 9.2 11.1 10.4 7.2 7.6 9.5 10.2 11.7 8.1 9.8 5.2 11.0 8.6 10.1 7.0 8.3 8.4 8.5 5.8 9.1 5.2 10.2 10.1 7.2 7.6 8.7 10.3 11.5 13.6 7.0 7.9 8.4 8.2 9.6 19.9 7.6 36.4 25.8 19.5 23.0 9.0 15.6 17.2 10.8 15.6 11.3 7.1 16.9 14.1 21.4 11.8 13.2 21.4 21.0 24.4 22.4 10.4 18.8 9.7 15.9 15.8 38.3 7.8 14.8 23.0 12.6 32.0 16.0 27.8 6.6 26.5 47.5 17.2 9.5 18.9 14.7 9.5 12.2 10.2 121.1 30.3 42.5 18.7 16.9 12.1 30.1 26.8 12.4 13.9 18.6 8.8 25.1 23.9 27.8 14.2 11.7 21.1 25.6 9.5 25.4 11.8 24.1 16.9 0.7 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.5 0.1 0.2 0.4 0.1 9.1 9.1 9.2 8.5 8.4 9.2 9.5 10.2 8.6 10.1 10.3 9.6 35.7 48.1 22.7 68.2 11.9 21.9 15.1 19.8 24.5 28.8 24.1 19.7 18.1 25.8 31.8 16.5 25.0 13.3 18.2 20.8 3.9 13.4 7.0 29.0 59.2 30.8 24.0 23.1 106.7 12.9 7.5 33.1 10.2 32.4 14.5 16.8 24.3 30.0 12.9 15.2 92.6 17.1 26.4 17.2 16.2 5.6 20.5 14.2 26.6 67.5 19.4 17.7 15.5 121.2 109.6 18.8 7.0 24.8 18.1 48.5 8.7 15.9 30.6 14.5 0.0 35.4 26.9 26.2 12.0 23.4 24.6 25.3 14.5 21.8 10.4 25.3 GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.8;ovary: 73.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.6;Gastric mucus-secreting cells: 100.9;Granulosa cells: 52.9" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Cell line enhanced" "Detected in many" "BEWO: 54.8;CACO-2: 69.7;hTERT-RPE1: 25.5;OE19: 37.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB011581: AB_732529, HPA066629: AB_2685695" "unprognostic (1.90e-1)" "unprognostic (1.14e-1)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.72e-2)" "unprognostic (2.16e-1)" "unprognostic (9.43e-2)" "unprognostic (4.36e-2)" "unprognostic (3.47e-1)" "unprognostic (2.61e-1)" "unprognostic (8.45e-3)" "prognostic unfavorable (1.92e-9)" "unprognostic (8.75e-3)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-2)" 22.2 57.8 0.0 2.5 0.2 0.0 3.8 0.0 0.3 4.9 2.8 11.4 22.8 19.8 1.2 0.8 28.9 11.1 43.9 0.1 0.0 3.0 12.6 14.8 1.9 0.1 0.0 73.0 22.7 0.3 0.6 6.5 0.0 5.5 11.0 0.1 0.8 0.7 0.8 1.5 20.7 9.5 0.2 15.0 49.6 6.3 0.1 0.4 5.3 0.6 0.2 23.0 3.2 0.0 10.1 1.4 0.0 0.0 2.1 1.0 54.8 0.3 0.4 0.8 1.0 69.7 3.8 0.0 3.2 1.2 3.4 10.8 0.4 4.5 1.4 0.0 13.6 0.0 4.3 6.1 14.3 0.6 0.6 0.4 8.9 12.1 9.1 25.5 9.5 0.0 0.5 0.0 0.0 1.5 0.0 0.2 0.1 37.6 9.8 0.0 1.1 0.2 0.4 2.8 0.9 0.1 10.7 6.1 3.0 2.7 1.7 0.0 0.7 1.4 1.6 11.4 1.7 0.0 0.0 0.0 6.2 0.3 9.9 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 7.3 44.8 30.2 0.0 0.0 0.9 4.0 4.6 1.8 0.0 3.4 2.7 97.6 30.0 6.1 0.0 0.0 0.9 0.9 50.0 0.0 28.4 44.7 6.3 6.3 11.5 26.0 2.7 0.1 19.6 11.2 24.4 100.9 16.6 5.1 52.9 28.5 11.1 1.6 0.0 0.1 45.8 2.0 0.6 0.9 8.8 3.4 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.2 36.8 27.7 10.1 0.2 4.1 43.3 0.0 3.9 0.0 32.9 0.4 8.6 1.4 1.4 0.9 0.9 1.9 1.3 11.4 47.2 2.9 CTAGE1 "CT21.1, CT21.2, CTAGE, cTAGE-1, cTAGE-2" ENSG00000212710 "Cutaneous T cell lymphoma-associated antigen 1" "Q96RT6, Q9HC47" 18 22413599-22417915 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "testis: 10.3" "Group enriched" "Detected in some" 4 "Early spermatids: 117.4;Spermatocytes: 36.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000387, HPA000922, CAB016204" Uncertain NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "CAB016204: AB_673617, HPA000387: AB_1078582, HPA000922: AB_1078581" "unprognostic (1.41e-1)" "unprognostic (5.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.81e-2)" "unprognostic (1.52e-1)" "unprognostic (1.70e-2)" "unprognostic (3.15e-1)" "unprognostic (1.63e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.1 0.0 0.1 0.0 0.0 0.5 0.4 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.3 16.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.5 0.5 36.1 0.8 0.0 0.3 0.1 0.1 0.1 0.0 0.6 RBBP8 "COM1, CtIP, RIM, SCKL2" ENSG00000101773 "RB binding protein 8, endonuclease" Q99708 18 22798261-23026488 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 125.9;Spermatocytes: 116.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 36.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039890, HPA052946" Approved Supported Nucleoplasm NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA039890: AB_10794756, HPA052946: AB_2681996" "unprognostic (1.55e-3)" "unprognostic (4.10e-3)" "unprognostic (7.89e-2)" "unprognostic (1.01e-1)" "unprognostic (2.44e-1)" "unprognostic (7.28e-2)" "unprognostic (3.60e-3)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (2.29e-2)" "unprognostic (1.58e-3)" "unprognostic (1.04e-2)" "prognostic favorable (1.71e-5)" "unprognostic (3.91e-3)" "unprognostic (2.42e-2)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" 10.1 8.7 6.8 10.0 6.8 18.2 29.4 9.2 11.3 20.9 41.6 14.5 9.3 20.1 23.4 22.1 28.0 12.7 7.0 7.4 9.2 42.2 14.4 13.5 14.0 6.3 7.3 6.4 18.5 22.1 17.5 8.5 6.4 10.8 12.9 6.2 19.5 23.3 2.3 28.5 12.9 16.4 6.2 7.6 13.1 28.7 8.5 32.4 18.2 3.5 17.3 18.3 18.0 7.3 32.9 24.8 36.0 41.9 18.2 19.4 28.2 44.2 31.1 40.3 56.5 45.7 36.3 95.4 19.9 27.9 38.5 67.3 41.2 89.9 78.5 68.3 33.2 41.8 32.0 44.0 22.2 151.5 43.7 13.9 86.0 61.0 105.3 23.6 16.6 65.7 25.0 69.2 41.6 49.1 112.8 50.6 34.2 60.1 41.5 57.6 65.9 58.9 117.4 34.7 84.1 39.8 74.1 22.4 39.0 20.5 129.1 39.4 12.0 107.2 49.3 52.4 78.0 92.9 108.4 105.3 49.1 72.2 58.8 17.0 6.5 3.9 1.2 24.0 0.5 6.6 1.7 2.1 8.2 5.3 0.9 1.5 2.4 7.9 36.7 8.1 4.7 3.8 6.8 6.8 9.2 11.3 7.4 9.2 6.3 7.3 6.4 6.2 8.5 7.3 13.1 35.3 42.8 10.1 22.9 27.4 44.7 125.9 76.8 4.3 22.6 72.6 10.4 35.8 41.9 29.5 4.2 12.7 25.0 14.5 43.0 30.5 17.7 56.0 19.5 14.2 7.7 37.0 20.3 33.0 9.4 13.2 23.0 67.3 66.1 22.3 5.7 16.4 11.7 1.7 15.5 9.3 16.2 11.4 23.5 14.5 6.5 27.5 23.2 8.4 9.0 2.1 4.1 9.5 2.7 44.9 8.6 5.3 53.8 37.5 17.5 26.1 28.2 7.9 0.0 20.4 14.0 116.6 83.4 36.2 19.7 15.2 13.6 9.8 14.9 45.5 CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260467 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.2" "Cell type enhanced" "Detected in many" "Astrocytes: 258.2;Glandular and luminal cells: 54.3;Oligodendrocyte precursor cells: 163.3" "Cancer enriched" "Detected in all" 5 "melanoma: 38.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "SK-MEL-30: 154.3;U-266/70: 216.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073649 Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA073649: AB_2732233" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (1.56e-1)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.10e-3)" "unprognostic (1.42e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "prognostic favorable (4.71e-6)" "unprognostic (1.00e-1)" "unprognostic (1.60e-1)" "unprognostic (4.80e-2)" "unprognostic (7.81e-2)" 17.1 3.3 63.9 2.1 67.9 2.6 13.8 36.8 54.8 6.9 17.1 5.2 7.5 9.4 3.2 6.9 10.9 5.2 4.6 44.9 53.5 13.1 9.9 21.5 2.8 39.6 59.0 3.7 3.0 21.9 4.0 10.4 40.8 3.7 5.1 8.0 22.3 4.5 1.5 17.2 6.7 6.6 31.2 3.7 14.5 3.5 70.2 4.9 15.0 1.8 2.3 5.4 7.8 33.3 13.1 14.4 11.8 0.9 7.1 0.3 20.4 3.1 17.3 4.2 2.5 9.5 23.0 0.7 13.3 14.9 42.3 11.4 9.0 2.3 3.2 0.3 19.4 1.0 38.7 37.1 6.2 2.5 1.0 4.2 2.1 5.3 6.1 26.8 47.1 2.3 0.5 16.2 11.7 30.2 0.1 8.8 7.5 64.5 46.6 3.1 42.2 50.6 21.2 31.5 11.2 8.2 26.1 32.5 154.3 8.3 52.4 7.2 79.3 47.9 0.5 1.6 3.8 216.0 88.9 27.4 0.2 19.2 16.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 63.9 67.9 36.8 54.8 44.9 53.5 39.6 59.0 40.8 31.2 70.2 33.3 2.9 22.4 27.4 258.2 3.8 5.1 2.0 1.4 5.2 4.1 9.2 6.7 1.4 7.2 2.3 3.7 29.2 0.9 1.3 8.5 1.9 1.1 2.0 11.6 4.4 6.0 3.5 1.3 19.2 2.3 1.1 4.1 10.2 54.3 0.0 14.8 25.0 9.3 16.6 0.0 22.2 4.6 0.0 3.5 3.1 3.5 0.0 4.7 28.4 41.2 0.0 1.4 0.0 163.3 1.4 2.4 5.2 6.0 3.6 0.6 6.7 14.3 1.8 18.7 0.0 5.0 2.1 0.2 3.2 1.6 6.7 0.3 1.4 0.5 2.1 2.2 TMEM241 "C18orf45, FLJ44259, MGC11386" ENSG00000134490 "Transmembrane protein 241" Q24JQ0 18 23197144-23437961 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.8;Oligodendrocyte precursor cells: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029489, HPA059922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" Vesicles "HPA029489: AB_2673067, HPA059922: AB_2684164" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (7.80e-2)" "unprognostic (1.02e-2)" "unprognostic (1.37e-1)" "unprognostic (6.48e-2)" "unprognostic (1.15e-4)" "unprognostic (7.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-3)" "unprognostic (9.53e-3)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (2.95e-1)" "unprognostic (4.93e-1)" "prognostic unfavorable (5.80e-4)" 2.1 0.6 0.7 1.8 0.9 1.1 2.3 0.0 1.7 1.8 0.7 1.7 1.5 2.0 1.6 1.7 1.7 1.6 1.5 1.5 0.2 1.1 1.7 1.4 1.4 0.1 0.1 1.6 1.3 2.4 1.1 2.3 0.0 0.9 2.2 0.3 1.2 0.9 1.0 0.8 1.1 2.9 0.0 1.5 1.4 0.6 0.2 1.0 2.2 0.9 1.5 1.6 1.0 1.1 3.2 4.5 1.2 4.1 5.5 5.3 3.5 1.6 1.9 1.9 3.8 1.3 7.6 13.1 3.4 2.7 6.6 6.0 2.9 7.8 5.3 1.4 1.5 2.4 4.5 3.7 3.3 2.7 2.1 5.3 6.5 6.3 6.6 4.1 6.6 6.3 5.5 4.1 5.3 4.6 2.6 0.5 1.8 10.6 2.9 1.9 5.8 11.2 2.6 1.9 4.6 4.3 7.1 3.2 4.2 4.3 4.0 0.8 3.0 10.3 2.4 3.6 3.9 8.4 8.1 5.3 5.1 8.4 7.2 1.2 0.5 0.0 0.9 2.2 1.3 1.3 0.2 0.9 2.0 2.2 0.8 1.2 0.0 6.0 0.8 0.7 1.2 1.1 0.7 0.9 0.0 1.7 1.5 0.2 0.1 0.1 0.0 0.0 0.2 1.1 3.7 0.0 6.9 4.9 3.5 2.8 3.3 3.9 4.0 1.0 16.1 7.9 1.4 1.5 5.2 3.7 4.2 8.3 4.7 1.8 0.0 2.3 0.0 2.4 4.6 2.5 1.2 3.8 70.8 2.2 8.7 3.9 7.1 3.2 2.5 4.2 3.3 3.8 3.1 10.1 16.0 4.0 6.1 0.6 2.9 0.3 1.8 2.4 1.8 11.2 1.4 1.0 5.2 21.6 9.9 3.0 3.1 1.2 5.7 4.6 2.0 3.3 8.3 1.3 0.0 4.2 3.0 1.4 5.5 6.2 4.4 4.7 2.1 4.2 2.3 2.9 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23453287-23486603 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 174.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 23.1 18.5 5.5 20.4 7.1 174.3 19.2 7.9 10.2 17.4 8.3 47.5 51.6 16.7 12.4 65.5 14.8 24.3 32.7 5.9 6.7 29.6 55.6 22.7 22.8 9.3 7.3 15.7 27.6 22.8 5.4 34.9 8.9 20.1 43.5 19.6 23.2 14.5 52.9 33.3 62.5 19.7 7.5 21.5 38.5 36.6 6.9 21.5 22.2 48.8 30.2 25.8 27.0 10.6 41.9 15.7 17.8 25.0 31.8 37.7 28.5 38.9 29.8 27.6 28.4 17.3 47.5 27.6 52.3 43.7 26.9 57.6 25.9 45.4 38.9 29.5 12.0 25.9 26.9 22.2 71.7 74.7 25.8 39.0 91.2 44.1 66.7 36.7 38.4 19.2 39.8 34.7 45.0 19.4 25.8 15.6 17.6 59.0 31.3 31.3 33.2 41.2 39.3 50.0 39.5 28.9 50.1 28.4 37.4 41.0 21.9 45.0 63.7 48.4 10.9 21.2 28.9 66.1 56.0 38.2 31.0 36.7 38.2 50.1 24.5 14.8 15.0 34.6 10.8 14.0 12.3 12.6 19.1 18.5 9.8 11.2 17.2 15.0 39.0 8.6 19.4 20.7 5.5 7.1 7.9 10.2 5.9 6.7 9.3 7.3 8.9 7.5 6.9 10.6 49.7 80.1 57.7 23.2 46.4 120.4 92.4 78.6 113.8 44.1 49.3 35.6 69.1 51.5 81.5 25.8 56.3 43.0 74.6 338.1 25.4 51.0 271.5 130.1 85.5 44.1 62.8 259.8 35.5 52.7 64.6 48.8 93.8 267.2 63.3 40.0 29.6 88.5 41.1 28.6 34.2 119.9 50.8 59.9 51.2 305.8 22.4 85.7 42.7 15.9 80.6 18.3 53.5 34.2 49.5 148.4 210.7 30.1 63.4 118.5 199.5 52.5 72.3 46.4 6.6 43.9 51.6 28.4 10.1 164.2 143.6 88.4 57.3 71.1 77.2 244.4 RMC1 "C18orf8, HsT2591, MIC1, WDR98" ENSG00000141452 "Regulator of MON1-CCZ1" Q96DM3 18 23503470-23531822 "Cancer-related genes, Predicted intracellular proteins" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 14.5;Proximal tubular cells: 19.9;Syncytiotrophoblasts: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043589 Uncertain Uncertain Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA043589: AB_2678568" "unprognostic (6.45e-2)" "unprognostic (6.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (5.51e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (4.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.73e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-1)" "unprognostic (3.03e-1)" "unprognostic (3.76e-1)" "unprognostic (1.25e-1)" "unprognostic (3.04e-2)" "unprognostic (4.13e-2)" 12.8 9.8 4.9 11.2 6.0 27.4 11.2 5.5 7.3 10.9 8.5 11.1 16.7 11.2 9.3 11.7 10.6 10.3 8.8 6.2 6.6 13.0 19.1 14.4 21.3 5.3 4.8 9.6 11.7 11.4 16.6 8.5 5.7 9.3 10.9 25.4 12.2 10.6 13.4 12.5 17.1 10.6 5.1 15.6 14.6 17.2 5.3 15.8 9.8 7.4 19.1 14.8 10.5 7.2 13.9 13.9 10.3 18.1 23.0 16.6 13.5 21.5 22.8 28.2 33.6 12.9 8.1 20.8 17.5 18.7 40.9 26.6 27.1 12.0 24.8 21.6 15.4 10.2 8.7 13.1 30.1 27.7 36.0 14.9 18.6 35.2 19.8 16.2 16.9 17.7 16.7 21.9 18.8 18.1 23.8 13.0 5.6 19.7 21.4 18.3 15.4 20.4 14.7 13.0 13.8 17.9 28.1 13.7 18.2 14.2 10.5 17.6 16.2 23.6 6.0 9.8 18.6 34.1 27.4 23.6 24.5 18.7 18.4 50.5 16.4 37.7 23.8 31.0 24.5 32.5 20.7 23.3 20.0 29.5 14.0 17.2 15.2 32.9 44.5 44.5 30.5 18.7 4.9 6.0 5.5 7.3 6.2 6.6 5.3 4.8 5.7 5.1 5.3 7.2 9.1 9.6 13.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.6 5.8 0.0 0.0 3.7 7.3 0.0 10.7 13.4 0.0 5.9 11.6 0.0 11.4 5.9 2.9 0.0 0.0 0.0 12.1 7.6 3.4 0.0 14.5 3.8 8.7 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 8.8 0.0 0.0 0.0 0.0 11.3 0.0 0.0 1.9 0.0 0.0 19.9 1.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 19.2 6.3 8.3 0.0 0.0 NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 70.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 273.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" 17.5 76.7 35.1 16.9 69.6 42.6 20.0 55.3 47.8 16.7 28.6 13.7 14.5 16.7 15.0 20.5 13.4 15.3 11.5 41.1 44.3 16.8 15.2 29.0 20.4 73.3 55.8 16.0 11.9 72.6 15.0 27.8 66.6 13.1 12.0 28.0 36.8 13.2 22.9 24.3 17.8 15.1 49.8 17.1 20.4 13.7 55.8 12.2 11.8 14.1 15.6 15.8 18.0 110.6 21.5 41.4 17.8 29.3 55.8 44.6 40.7 37.3 81.1 38.8 84.3 28.1 30.7 18.4 28.0 55.0 132.8 59.3 22.6 63.2 35.2 15.0 17.9 6.8 35.7 63.2 79.2 25.0 28.5 42.2 61.3 81.7 273.2 76.8 40.3 20.7 20.1 47.5 44.2 32.4 10.6 14.9 12.5 24.4 37.3 15.3 28.1 45.0 88.8 51.9 7.5 14.5 44.6 62.0 54.3 27.7 15.9 19.5 50.0 81.1 15.3 32.4 32.3 29.7 97.1 12.2 177.7 21.8 37.1 4.4 9.0 8.8 29.7 8.7 20.5 5.0 12.4 20.7 4.0 6.7 5.5 15.0 7.9 10.5 13.8 70.9 17.4 10.6 35.1 69.6 55.3 47.8 41.1 44.3 73.3 55.8 66.6 49.8 55.8 110.6 18.4 25.6 56.1 32.7 9.6 9.3 34.1 16.5 8.0 6.7 10.5 9.4 4.4 11.5 21.8 9.2 18.8 15.1 61.0 24.8 0.0 11.2 1.2 23.3 12.2 16.4 3.6 2.5 23.8 15.1 7.8 13.0 15.3 53.9 10.8 31.6 6.8 9.8 28.9 3.3 20.2 7.3 2.0 11.9 6.5 1.5 9.0 21.0 12.4 59.0 7.2 15.1 25.7 39.2 182.0 34.4 22.6 10.5 15.6 41.5 8.3 5.4 10.0 12.7 0.0 10.3 14.4 13.9 25.1 17.6 14.5 23.8 19.1 52.4 7.6 64.0 ANKRD29 FLJ25053 ENSG00000154065 "Ankyrin repeat domain 29" Q8N6D5 18 23598926-23662911 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 163.8;Alveolar cells type 1: 218.0;Cone photoreceptor cells: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 16.7;BJ hTERT+: 16.6;hTCEpi: 16.2;PC-3: 15.5;U-2197: 20.5;U-87 MG: 21.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041272, HPA049419" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nuclear bodies" "HPA041272: AB_2677387, HPA049419: AB_2680757" "unprognostic (4.52e-3)" "unprognostic (8.37e-2)" "unprognostic (7.04e-2)" "unprognostic (1.78e-1)" "unprognostic (2.01e-3)" "prognostic favorable (1.92e-5)" "unprognostic (3.29e-2)" "prognostic favorable (5.98e-5)" "unprognostic (1.11e-1)" "unprognostic (1.93e-2)" "unprognostic (3.83e-2)" "unprognostic (3.54e-1)" "prognostic favorable (7.20e-5)" "unprognostic (1.10e-2)" "unprognostic (9.46e-2)" "unprognostic (7.36e-2)" "unprognostic (1.64e-5)" 17.8 7.2 14.1 3.6 6.4 0.2 15.8 9.1 13.5 12.9 10.7 4.7 1.5 15.7 5.3 9.4 13.8 5.6 6.8 13.5 10.4 3.6 1.9 31.3 20.1 11.6 14.8 14.5 1.0 24.8 8.1 0.1 11.5 8.3 2.2 4.9 7.5 8.8 4.4 4.4 6.6 11.7 6.8 2.6 15.1 3.7 9.4 3.8 3.3 3.9 14.3 6.6 13.0 10.1 2.4 6.7 0.0 0.0 1.6 16.7 0.1 6.6 16.6 2.6 3.3 3.0 0.6 0.0 0.9 3.2 12.9 3.4 0.0 8.7 0.6 0.2 5.9 0.0 4.3 0.2 0.3 0.0 0.5 4.4 16.2 2.6 4.4 2.4 1.7 0.0 0.0 0.4 4.4 0.7 0.0 0.0 1.2 5.7 15.5 0.0 0.4 1.5 4.1 2.4 1.0 8.0 1.7 0.3 0.1 0.3 1.9 0.1 3.9 0.4 2.3 20.5 6.0 0.0 0.0 0.0 21.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 14.1 6.4 9.1 13.5 13.5 10.4 11.6 14.8 11.5 6.8 9.4 10.1 163.8 218.0 38.7 27.4 0.2 5.1 10.1 5.0 5.2 6.0 5.1 16.6 9.7 8.6 6.3 1.8 66.7 0.0 1.1 0.3 5.9 2.5 40.0 10.2 18.7 39.0 1.8 0.4 22.1 1.1 0.0 6.6 25.5 0.8 3.8 9.7 15.4 0.9 2.3 42.1 27.6 1.7 0.0 0.8 3.3 25.2 7.2 3.6 7.2 22.5 0.2 1.3 0.0 8.5 1.3 11.4 1.2 20.3 1.5 5.1 11.5 10.1 1.6 4.3 13.1 12.1 40.6 2.3 2.6 20.1 2.8 0.0 0.8 21.5 2.5 3.6 LAMA3 "BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa" ENSG00000053747 "Laminin subunit alpha 3" Q16787 18 23689453-23956222 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Epidermolysis bullosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 171.0;Gastric mucus-secreting cells: 138.1;Pancreatic endocrine cells: 585.5;Paneth cells: 170.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "HBEC3-KT: 1237.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA009309, CAB010757" Uncertain Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 1800000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" "CAB010757: AB_477162, HPA009309: AB_1079224" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (6.36e-2)" "unprognostic (3.82e-3)" "unprognostic (2.08e-1)" "unprognostic (1.11e-1)" "unprognostic (1.83e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (7.09e-3)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.98e-1)" "unprognostic (2.36e-1)" "unprognostic (3.15e-1)" "unprognostic (9.91e-3)" "unprognostic (3.98e-2)" "unprognostic (1.13e-1)" 10.0 1.2 8.3 8.5 3.6 0.1 20.3 2.8 5.9 15.4 5.4 13.6 17.8 15.6 4.7 14.5 12.0 7.4 4.2 4.1 3.5 3.2 1.7 20.9 4.1 3.8 5.9 5.7 4.7 10.9 3.0 24.8 3.6 12.2 8.4 3.7 21.3 13.5 2.0 32.1 19.7 6.9 3.5 0.8 31.8 3.3 4.3 9.5 2.3 1.7 4.1 12.2 23.1 2.9 140.5 15.7 0.1 0.1 6.9 1.3 0.3 2.6 1.8 1.3 1.7 5.4 159.5 0.1 17.3 1.8 0.4 248.5 0.2 1237.9 0.9 0.2 8.8 0.0 5.6 2.8 1.2 0.0 0.6 1.6 139.1 0.8 140.0 0.9 5.2 0.2 0.0 0.2 1.6 0.4 0.1 0.1 1.4 42.6 14.4 2.6 0.1 0.2 51.8 15.4 0.6 2.5 4.9 2.0 0.4 0.3 4.5 1.8 12.3 0.9 1.0 6.7 0.6 0.2 0.1 0.6 2.9 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.3 3.6 2.8 5.9 4.1 3.5 3.8 5.9 3.6 3.5 4.3 2.9 28.8 115.4 26.4 13.1 0.7 31.4 104.2 117.1 100.7 6.0 21.8 41.8 2.3 4.3 20.4 1.8 0.0 0.6 0.5 171.0 0.0 30.2 3.9 21.5 4.3 7.5 8.3 0.0 8.3 34.4 0.4 3.6 138.1 24.0 5.7 9.5 2.5 0.9 0.2 0.0 18.5 23.7 4.1 0.0 1.5 4.5 5.9 2.0 1.8 68.4 0.6 0.2 0.0 1.0 2.0 585.5 170.1 3.4 0.2 45.6 39.5 0.0 15.6 2.2 6.6 1.5 22.1 4.5 4.0 28.2 9.9 0.1 1.5 5.9 28.4 18.2 TTC39C "C18orf17, FLJ33761, HsT2697" ENSG00000168234 "Tetratricopeptide repeat domain 39C" Q8N584 18 23992773-24135610 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 94.2;retina: 143.2" "Cell type enhanced" "Detected in many" "Early spermatids: 149.8;Hepatocytes: 169.3;Late spermatids: 320.0;Rod photoreceptor cells: 241.5" "Cancer enriched" "Detected in all" 4 "liver cancer: 19.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 115.9" "Lineage enriched" "Detected in all" 4 "T-cells: 115.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065705, HPA065713" Approved Approved Nucleoplasm NA NA "Cluster 13: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA065705: AB_2685538, HPA065713: AB_2685542" "prognostic favorable (1.48e-4)" "unprognostic (6.37e-2)" "unprognostic (3.66e-1)" "unprognostic (9.97e-2)" "unprognostic (4.37e-2)" "unprognostic (2.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.30e-3)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.60e-5)" "unprognostic (2.32e-1)" "unprognostic (3.51e-1)" "unprognostic (8.94e-3)" "unprognostic (4.48e-3)" 21.1 30.5 6.7 12.3 6.4 36.3 18.9 3.2 26.2 20.1 10.8 10.9 9.1 15.6 7.4 16.0 18.6 23.6 7.2 19.9 4.5 6.1 94.2 15.1 19.0 1.6 2.5 10.2 15.8 1.9 20.1 2.7 0.6 20.0 7.4 143.2 25.2 5.4 10.2 56.1 13.4 8.3 2.1 13.2 12.8 33.3 3.6 15.4 7.1 1.6 21.3 13.3 19.6 5.3 12.6 10.4 6.1 3.7 38.3 39.8 22.9 16.4 39.0 13.9 13.5 1.3 6.8 19.7 16.8 30.4 11.1 15.8 12.3 16.5 10.9 28.7 13.1 6.6 50.6 26.3 7.7 31.4 15.3 33.4 21.8 8.4 11.7 26.9 1.1 14.6 0.1 0.2 8.7 10.7 4.9 10.0 14.5 5.5 25.1 28.1 9.5 7.8 14.7 19.7 15.9 12.4 34.5 10.6 11.4 6.5 8.2 10.6 8.3 11.8 9.6 8.7 8.7 0.4 0.1 32.0 16.0 32.9 8.3 2.4 5.4 0.2 32.8 6.1 84.0 16.4 71.7 40.3 7.8 10.0 30.0 25.0 1.5 18.5 5.2 27.8 115.9 13.1 6.7 6.4 3.2 26.2 19.9 4.5 1.6 2.5 0.6 2.1 3.6 5.3 6.9 0.0 3.4 13.7 23.0 46.0 17.1 10.1 30.1 14.7 28.6 24.1 3.0 64.3 5.0 7.3 45.9 0.7 52.0 2.0 0.0 14.2 149.8 72.9 34.9 7.0 4.2 20.6 114.3 11.5 15.2 16.5 15.8 30.0 2.5 11.5 4.6 169.3 12.6 13.5 80.3 9.4 18.3 26.6 44.5 320.0 11.1 21.5 14.2 20.6 18.9 27.8 38.1 41.7 2.3 8.9 1.5 7.9 7.1 20.8 11.4 1.3 16.7 241.5 0.0 5.2 6.7 42.4 8.0 26.8 86.1 0.5 95.9 9.2 9.0 20.1 CABYR "CBP86, CT88, FSP-2" ENSG00000154040 "Calcium binding tyrosine phosphorylation regulated" O75952 18 24138987-24161600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 28 "testis: 303.5" "Group enriched" "Detected in many" 18 "Early spermatids: 2505.6;Late spermatids: 3543.7" "Cancer enhanced" "Detected in many" "testis cancer: 8.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 4.8;memory B-cell: 4.7;naive B-cell: 5.0;neutrophil: 1.9" "Group enriched" "Detected in many" 6 "B-cells: 5.0;granulocytes: 4.8" "Cell line enhanced" "Detected in many" "SiHa: 26.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA040703, HPA047801" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA040703: AB_2677087, HPA047801: AB_2680159" "unprognostic (1.18e-3)" "unprognostic (4.18e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-1)" "unprognostic (5.26e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.46e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-2)" "unprognostic (7.24e-3)" "unprognostic (1.58e-1)" "unprognostic (3.21e-4)" "unprognostic (2.52e-2)" "unprognostic (5.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 1.5 3.3 5.4 1.2 6.6 1.1 5.2 3.7 9.4 6.8 10.9 1.2 1.0 2.9 2.0 1.7 3.6 1.8 0.9 7.5 8.0 0.8 1.1 1.0 1.2 6.5 4.2 1.7 0.7 0.4 8.3 0.9 7.0 2.3 1.1 5.7 2.1 1.5 1.0 2.1 1.1 3.6 3.7 1.2 1.5 303.5 5.2 1.5 1.0 0.1 1.0 2.4 1.4 10.5 4.9 11.9 3.4 1.7 3.4 9.1 14.7 8.2 5.4 10.2 10.6 2.5 9.2 0.2 6.8 12.6 0.5 4.5 3.4 6.9 10.7 0.6 5.6 0.3 6.9 2.3 4.8 0.4 0.5 11.2 11.1 12.7 3.3 4.8 2.9 0.6 0.0 0.3 2.6 1.4 0.1 0.4 11.3 0.5 7.4 0.7 0.4 0.2 4.2 5.5 7.2 8.3 26.8 5.2 0.5 2.0 11.3 1.2 1.7 0.8 2.3 3.4 0.2 0.3 0.3 0.1 4.7 0.9 0.5 4.8 0.3 0.6 0.2 0.2 0.1 4.7 0.3 0.3 0.1 5.0 0.3 0.6 1.9 0.8 0.4 0.4 0.2 0.4 5.4 6.6 3.7 9.4 7.5 8.0 6.5 4.2 7.0 3.7 5.2 10.5 1.1 0.0 0.0 1.6 1.0 0.3 0.9 7.2 1.2 2.0 3.1 7.1 0.8 0.0 1.9 0.0 2.1 0.2 0.3 2.2 0.0 0.8 2505.6 76.2 3.3 2.0 0.0 0.4 10.7 0.2 0.5 0.9 0.0 5.1 0.0 0.9 0.4 0.0 0.6 0.0 9.9 1.9 6.1 0.0 0.7 3543.7 23.3 2.4 1.8 2.8 0.0 0.0 1.0 7.5 12.6 0.4 1.3 21.8 0.0 0.1 0.2 0.1 2.8 2.1 19.7 0.7 2.0 166.3 19.1 0.5 0.0 0.0 0.5 0.9 0.4 0.3 OSBPL1A "ORP-1, ORP1, OSBPL1B" ENSG00000141447 "Oxysterol binding protein like 1A" Q9BXW6 18 24162045-24397880 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 214.3;Oligodendrocytes: 433.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 22 "basophil: 93.4" "Lineage enriched" "Detected in many" 22 "granulocytes: 93.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040959, HPA043401" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA040959: AB_10964295, HPA043401: AB_10960208" "unprognostic (1.75e-2)" "unprognostic (3.35e-2)" "unprognostic (9.84e-3)" "unprognostic (4.92e-3)" "unprognostic (2.34e-1)" "unprognostic (3.06e-2)" "unprognostic (5.82e-2)" "unprognostic (2.06e-1)" "unprognostic (5.88e-2)" "unprognostic (2.62e-2)" "unprognostic (2.41e-1)" "unprognostic (8.53e-2)" "prognostic favorable (4.98e-13)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.18e-2)" "unprognostic (5.42e-3)" "unprognostic (1.56e-1)" 72.0 27.8 77.1 9.4 105.6 15.4 47.9 99.6 136.0 52.4 114.0 34.9 20.7 48.0 17.2 30.8 29.6 21.1 52.0 77.3 90.6 43.5 13.3 24.2 10.4 89.7 95.0 27.3 16.5 62.8 18.7 8.3 94.5 23.0 22.7 82.2 51.5 26.2 170.9 17.5 20.2 41.1 79.2 9.9 21.3 14.3 91.3 9.6 29.0 123.1 7.9 25.4 20.0 136.8 38.2 11.4 26.3 49.1 60.0 48.7 24.5 14.0 40.4 12.4 10.2 7.1 38.9 0.1 16.0 25.1 19.7 37.9 10.4 24.4 11.4 0.2 19.6 12.1 7.8 0.2 29.9 30.4 6.0 63.4 34.4 9.5 38.4 54.0 15.9 10.4 0.0 0.3 15.5 16.1 7.0 9.1 21.7 19.5 36.8 0.0 21.0 3.2 3.3 27.7 16.9 16.6 32.6 37.5 46.1 24.5 13.7 21.7 3.4 45.9 9.4 14.9 13.6 0.4 5.3 1.0 22.3 8.7 26.8 93.4 4.2 1.1 0.2 2.2 0.1 0.0 0.8 0.6 4.1 0.4 0.6 0.5 1.6 0.2 0.7 4.1 0.8 1.5 77.1 105.6 99.6 136.0 77.3 90.6 89.7 95.0 94.5 79.2 91.3 136.8 214.3 16.0 21.6 142.0 5.4 20.1 43.4 16.6 29.6 66.6 73.6 64.3 78.0 41.5 20.0 20.2 22.9 12.1 11.1 23.6 64.6 13.3 67.7 27.6 55.3 89.9 4.8 18.7 180.3 7.4 8.1 59.9 16.3 17.0 17.2 137.9 37.5 12.4 26.6 25.2 166.4 40.0 40.7 27.4 17.9 76.4 42.9 34.3 58.7 67.5 11.0 124.8 0.0 75.9 433.0 10.7 19.1 54.9 2.5 27.1 29.8 71.7 21.7 112.3 32.9 44.7 65.8 6.7 9.9 27.2 10.2 6.4 3.8 103.7 16.2 26.4 IMPACT RWDD5 ENSG00000154059 "Impact RWD domain protein" Q9P2X3 18 24426634-24453531 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Stress response, Translation regulation" "Actin-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 83.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 65.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 65.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041045, HPA041968" Approved Approved Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA041045: AB_10793866, HPA041968: AB_10795603" "unprognostic (1.13e-1)" "unprognostic (8.59e-2)" "unprognostic (1.15e-2)" "unprognostic (1.62e-1)" "unprognostic (5.12e-2)" "unprognostic (7.94e-2)" "unprognostic (3.29e-2)" "unprognostic (6.14e-2)" "unprognostic (2.94e-2)" "unprognostic (2.15e-1)" "unprognostic (8.20e-2)" "unprognostic (1.22e-1)" "prognostic favorable (7.90e-4)" "unprognostic (5.60e-3)" "unprognostic (9.27e-2)" "unprognostic (1.99e-3)" "unprognostic (5.60e-3)" 19.3 21.0 10.1 12.0 11.5 15.8 25.1 11.2 10.4 15.5 9.6 18.0 16.1 16.4 18.9 21.7 14.2 12.7 19.3 8.6 18.1 24.4 22.3 15.7 11.5 12.2 14.7 17.1 20.5 27.8 10.0 15.0 12.2 18.0 14.9 10.1 25.0 16.0 20.3 11.4 16.5 13.0 12.2 15.2 15.9 34.5 21.9 11.2 32.5 13.1 12.0 12.7 8.0 12.5 27.8 15.6 26.4 33.0 25.2 37.8 43.1 36.4 43.1 20.1 19.9 5.4 23.8 16.7 35.8 38.9 12.4 31.9 9.1 40.3 29.7 0.1 8.2 24.9 14.9 8.8 38.0 99.0 23.1 33.0 30.6 13.4 82.1 24.2 38.7 0.0 21.2 0.2 33.6 25.6 0.2 17.5 44.0 48.8 17.1 0.1 51.6 8.4 22.0 43.2 21.8 26.9 51.6 22.6 37.7 20.8 31.9 33.2 48.0 80.5 10.4 15.3 15.6 31.0 43.0 0.3 32.4 12.3 35.5 65.8 9.6 18.4 4.2 12.2 5.6 4.0 5.5 4.1 12.3 5.3 5.6 4.7 1.5 9.0 9.0 8.5 8.0 6.0 10.1 11.5 11.2 10.4 8.6 18.1 12.2 14.7 12.2 12.2 21.9 12.5 20.8 19.2 14.9 11.1 10.9 11.3 11.5 23.5 18.2 11.3 34.6 26.0 30.4 17.2 22.9 14.7 2.1 30.7 11.0 10.8 37.2 19.5 17.2 21.2 24.2 18.8 15.6 23.3 7.6 22.4 20.2 20.1 16.8 13.7 20.3 43.3 15.0 33.5 26.4 5.0 13.7 25.6 26.4 19.8 10.4 21.0 16.1 21.6 19.6 5.6 25.3 41.7 7.2 10.1 9.9 20.2 7.1 27.1 11.1 15.1 17.3 47.8 25.4 11.0 13.1 15.3 21.0 83.9 75.6 27.0 14.5 16.4 10.3 52.5 21.9 10.2 HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Early spermatids: 1.2;granulocytes: 1.3;Late spermatids: 1.3;Melanocytes: 1.8;Spermatocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.1" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Cell line enhanced" "Detected in single" "HL-60: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035009 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" 0.1 0.1 0.2 0.4 0.1 0.8 0.0 0.3 0.3 0.1 0.3 0.1 0.5 0.2 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.3 0.6 0.5 0.1 0.0 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.2 0.0 1.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.2 0.1 212.9 0.1 61.1 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.2 0.5 0.5 0.2 0.1 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.2 0.0 0.6 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.3 0.4 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.7 1.3 0.0 0.1 1.8 1.0 0.0 0.3 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.8 0.3 1.3 0.3 0.0 0.6 0.0 0.5 0.2 0.0 0.4 ZNF521 "EHZF, Evi3" ENSG00000198795 "Zinc finger protein 521" Q96K83 18 25061924-25352190 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 95.9" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Microglial cells: 53.4;Oligodendrocyte precursor cells: 221.7;Oligodendrocytes: 104.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 95.9" "Group enriched" "Detected in some" 6 "basophil: 11.4;plasmacytoid DC: 8.8" "Group enriched" "Detected in many" 6 "dendritic cells: 8.8;granulocytes: 11.4" "Cell line enhanced" "Detected in many" "AF22: 67.6;fHDF/TERT166: 32.7;HUVEC TERT2: 46.9;THP-1: 38.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 49.7" "HPA023056, HPA023849" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA023056: AB_1859315, HPA023849: AB_1859316" "unprognostic (8.80e-3)" "unprognostic (9.68e-2)" "unprognostic (2.05e-1)" "unprognostic (3.40e-2)" "unprognostic (5.43e-2)" "unprognostic (3.73e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (8.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.19e-3)" "unprognostic (1.16e-3)" "unprognostic (2.43e-1)" "unprognostic (2.52e-3)" "unprognostic (7.82e-4)" 13.4 11.9 8.8 3.1 10.5 2.3 11.4 95.9 9.5 10.8 29.9 4.7 1.7 15.3 4.3 3.9 9.0 10.6 9.1 6.0 14.7 3.2 1.2 6.3 3.8 17.4 14.3 20.5 1.2 1.1 7.6 8.6 21.2 2.6 3.6 5.7 9.0 3.0 3.7 6.1 4.4 13.6 12.4 21.0 2.7 3.6 10.8 4.3 6.8 6.0 2.8 5.8 6.8 13.5 0.1 0.0 67.6 0.1 10.6 18.4 0.2 10.0 14.3 3.4 2.1 0.0 0.1 0.0 0.0 32.7 0.0 0.3 0.0 0.0 2.8 0.0 4.0 14.0 0.6 0.5 1.9 0.0 20.2 23.0 0.0 0.3 0.0 0.0 46.9 16.4 0.3 0.1 6.0 0.0 9.2 0.0 4.7 0.0 0.0 0.0 15.2 1.1 0.0 0.0 8.7 5.5 0.8 0.0 0.0 6.1 0.0 38.9 26.9 26.5 2.0 8.0 1.5 0.1 0.0 0.3 10.0 0.0 22.2 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 8.8 0.0 0.1 8.8 10.5 95.9 9.5 6.0 14.7 17.4 14.3 21.2 12.4 10.8 13.5 19.0 0.0 3.0 170.1 0.3 3.7 0.1 0.0 1.2 42.4 8.0 10.9 11.9 0.0 0.6 0.0 2.1 0.1 1.7 0.0 0.0 0.0 2.1 0.5 3.3 28.6 1.2 13.9 16.5 0.0 0.0 21.4 0.0 0.2 13.3 4.7 20.3 0.0 0.1 15.2 22.7 0.1 0.0 0.6 5.5 3.3 9.9 0.9 14.2 53.4 0.1 0.7 0.0 221.7 104.6 0.0 0.0 7.9 0.1 0.2 0.0 4.0 1.5 3.0 0.0 13.7 6.0 0.1 6.1 0.8 4.4 0.1 0.8 17.2 0.0 0.2 SS18 "SSXT, SYT" ENSG00000141380 "SS18 subunit of BAF chromatin remodeling complex" Q15532 18 26016253-26091217 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055741, HPA059539" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "HPA055741: AB_2682901, HPA059539: AB_2684055" "unprognostic (2.03e-2)" "unprognostic (1.76e-1)" "unprognostic (1.48e-2)" "unprognostic (1.95e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "unprognostic (4.59e-2)" "unprognostic (1.53e-2)" "unprognostic (1.63e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (2.47e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (1.40e-2)" "unprognostic (1.30e-1)" 29.5 46.2 21.2 27.7 24.9 23.0 33.2 23.6 22.6 32.1 26.3 28.4 18.0 32.2 39.4 34.5 33.2 29.8 29.4 21.8 23.6 36.8 41.9 26.8 35.9 25.5 24.7 47.7 23.8 52.0 30.5 36.9 24.5 35.0 23.4 24.7 29.7 31.2 11.6 41.2 27.7 31.8 23.8 28.5 26.8 25.9 22.4 33.6 45.4 17.5 38.6 38.3 31.2 29.1 52.4 37.2 90.8 43.9 69.0 65.1 45.8 62.9 57.6 55.1 53.6 24.5 43.1 90.6 49.1 75.0 49.0 67.1 50.1 62.0 67.5 58.4 23.3 45.4 56.2 39.8 55.6 69.8 66.5 81.4 71.3 68.6 74.3 53.7 43.7 26.6 34.2 45.0 76.3 53.1 28.5 39.9 17.3 51.6 35.7 33.0 70.2 44.2 57.6 60.7 38.1 57.7 96.0 43.8 27.0 64.6 45.5 40.9 51.4 114.1 22.6 26.8 63.9 80.9 58.3 64.0 53.9 47.8 62.2 27.1 13.5 19.4 16.4 19.7 19.2 17.7 15.6 17.1 15.2 15.0 16.2 18.6 5.7 24.6 20.2 8.5 18.2 16.3 21.2 24.9 23.6 22.6 21.8 23.6 25.5 24.7 24.5 23.8 22.4 29.1 28.8 28.9 23.7 43.8 45.9 8.9 27.8 13.9 40.9 28.8 29.4 26.4 16.0 22.8 18.1 23.9 16.7 70.0 34.0 25.2 21.5 30.3 52.7 44.8 31.5 27.9 24.7 26.1 50.7 26.0 48.8 30.4 22.4 32.3 36.8 60.2 22.1 34.5 27.6 87.5 42.7 25.7 6.1 25.5 10.9 51.4 33.2 22.6 5.4 65.6 19.7 51.1 22.6 90.5 118.0 34.8 15.7 41.0 42.0 24.8 19.1 24.9 30.5 29.8 39.5 23.4 31.3 29.3 20.3 37.2 13.2 85.1 34.0 30.7 16.9 24.7 PSMA8 "MGC26605, PSMA7L" ENSG00000154611 "Proteasome 20S subunit alpha 8" Q8TAA3 18 26133852-26193355 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 16.9" "Cell type enriched" "Detected in some" 6 "Spermatocytes: 229.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 72 "Daudi: 25.5;JURKAT: 7.1;U-266/70: 15.9;U-266/84: 17.2" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (5.39e-3)" "unprognostic (7.45e-5)" "unprognostic (2.94e-1)" "unprognostic (3.04e-2)" "unprognostic (1.59e-1)" "unprognostic (2.72e-1)" "unprognostic (1.99e-1)" "unprognostic (8.30e-2)" "unprognostic (7.54e-4)" "unprognostic (4.80e-2)" "unprognostic (1.15e-1)" "unprognostic (2.56e-1)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.1 16.9 0.0 0.5 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 17.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 1.4 0.8 1.2 0.0 1.2 0.9 1.9 0.1 0.4 0.0 0.7 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.5 0.4 0.1 0.0 0.0 10.3 0.0 0.0 0.1 0.0 0.4 0.6 0.0 2.8 0.1 0.0 0.0 0.0 0.3 0.7 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.2 6.9 1.2 0.3 1.8 1.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 1.5 2.4 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 229.1 37.2 0.0 0.0 1.0 0.7 0.5 0.0 0.0 TAF4B "TAF2C2, TAFII105" ENSG00000141384 "TATA-box binding protein associated factor 4b" Q92750 18 26226445-26391685 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 80.3;Plasma cells: 52.3;Suprabasal keratinocytes: 78.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 65.0;U-266/70: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028937 Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - Translation" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "HPA028937: AB_10603034" "unprognostic (2.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-3)" "unprognostic (1.74e-1)" "unprognostic (2.13e-1)" "unprognostic (5.01e-2)" "unprognostic (2.67e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-1)" "unprognostic (4.66e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (7.38e-2)" "unprognostic (9.56e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.72e-4)" 1.5 2.0 0.4 2.8 0.4 2.8 2.7 0.3 1.9 1.2 0.0 1.6 0.4 1.4 0.3 1.0 1.3 0.7 0.4 0.3 0.2 1.5 0.1 1.0 3.1 0.9 0.1 3.1 1.2 0.6 0.2 1.7 1.1 0.8 1.4 0.3 1.1 0.8 1.3 1.5 0.8 1.2 0.0 2.5 1.8 4.6 0.2 1.8 1.7 0.7 3.2 1.5 0.6 0.8 4.3 0.7 0.3 1.1 1.6 2.6 2.1 1.3 1.5 0.7 1.3 1.1 2.3 65.0 5.0 0.3 2.5 4.8 3.7 4.0 3.4 15.5 9.9 7.5 1.9 1.0 2.3 20.5 4.4 4.3 1.5 0.5 11.6 0.6 1.4 8.1 10.2 7.9 0.3 4.2 10.7 4.1 3.5 2.5 5.1 0.0 8.1 17.3 1.0 0.3 6.1 2.8 3.9 5.7 2.7 1.6 2.0 3.6 0.9 2.7 1.6 3.7 4.8 26.2 18.0 21.8 1.3 12.8 2.4 0.0 0.3 0.0 0.1 0.5 1.0 2.3 0.7 1.0 1.0 2.0 2.0 1.6 0.0 0.6 0.2 0.3 0.1 0.6 0.4 0.4 0.3 1.9 0.3 0.2 0.9 0.1 1.1 0.0 0.2 0.8 7.2 6.4 7.2 6.2 34.0 80.3 9.5 1.7 49.5 1.5 15.0 17.9 2.8 0.0 2.5 0.0 0.0 18.6 4.1 5.8 17.6 1.2 0.7 28.9 9.7 9.0 0.0 21.7 44.8 2.0 4.3 15.5 36.7 45.0 1.3 5.4 1.1 0.0 2.4 5.0 28.3 7.0 2.0 1.6 17.9 1.6 3.4 5.9 23.2 4.7 2.6 0.2 1.0 7.5 11.7 2.2 2.5 4.1 52.3 13.9 0.8 4.0 1.0 1.2 0.0 17.6 12.1 25.4 24.8 40.8 78.8 9.7 14.5 14.5 6.2 6.7 KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 106.4;Distal tubular cells: 117.4;Excitatory neurons: 283.7;Squamous epithelial cells: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.6;HaCaT: 113.5;hTCEpi: 100.6;RPTEC TERT1: 97.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.15e-3)" "unprognostic (5.66e-2)" "unprognostic (2.35e-4)" "prognostic unfavorable (2.22e-4)" "unprognostic (3.65e-3)" "unprognostic (7.43e-2)" "unprognostic (2.03e-3)" "unprognostic (6.77e-2)" "unprognostic (2.74e-1)" "unprognostic (1.88e-3)" "unprognostic (5.68e-3)" "unprognostic (1.77e-2)" "prognostic favorable (4.60e-8)" "unprognostic (3.87e-3)" "unprognostic (7.39e-2)" "unprognostic (1.50e-1)" "unprognostic (8.02e-2)" 7.8 16.5 21.7 2.7 41.5 0.6 32.4 14.0 44.3 19.2 9.5 9.7 4.1 14.2 22.6 50.6 50.2 8.4 23.8 31.2 10.3 28.8 3.5 5.5 2.7 9.8 13.6 15.1 7.4 12.0 10.8 11.4 9.2 21.6 10.6 18.4 19.9 22.6 5.1 61.1 3.7 12.5 10.2 3.9 10.3 5.9 13.7 17.6 19.9 6.9 14.3 13.0 36.9 29.6 17.5 55.1 106.6 11.6 61.8 9.7 13.4 14.3 21.5 22.0 21.9 5.1 19.1 2.9 52.2 30.5 18.0 113.5 20.5 30.6 20.6 2.2 8.7 3.1 10.2 8.2 11.1 1.7 4.7 16.7 100.6 6.2 41.4 28.0 21.0 24.1 1.3 1.2 16.0 24.5 16.3 5.2 10.5 57.1 27.1 8.5 5.7 2.3 97.8 25.2 10.3 40.5 20.7 27.5 8.7 61.3 24.1 4.0 11.7 24.4 6.8 4.8 15.0 4.8 4.1 0.4 8.7 11.0 36.8 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 41.5 14.0 44.3 31.2 10.3 9.8 13.6 9.2 10.2 13.7 29.6 3.0 3.2 4.1 80.0 0.7 31.7 55.9 17.2 106.4 5.0 27.3 29.7 13.9 8.6 15.0 25.8 8.4 45.5 0.8 6.2 117.4 8.3 28.0 47.0 7.8 2.9 1.2 0.8 283.7 3.6 7.6 5.5 7.1 42.4 0.0 66.3 2.5 1.7 4.4 21.9 66.1 4.3 20.3 0.8 1.7 12.0 5.3 1.2 23.2 16.9 0.4 21.4 1.0 81.4 42.1 11.8 2.4 3.0 6.6 36.4 0.4 10.7 29.3 5.9 0.0 2.7 6.2 1.8 5.1 109.0 44.5 33.2 1.0 6.3 4.0 51.2 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 CHST9 "GALNAC-4-ST2, GALNAC4ST-2" ENSG00000154080 "Carbohydrate sulfotransferase 9" Q7L1S5 18 26906481-27185308 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 13.8" "Cell type enhanced" "Detected in many" "Club cells: 115.2;Muller glia cells: 69.2;Oligodendrocyte precursor cells: 167.4;Respiratory ciliated cells: 311.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.3;Hep G2: 13.8;RPTEC TERT1: 41.8;SCLC-21H: 9.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA011393 Uncertain "Intracellular and membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA011393: AB_1846733" "unprognostic (9.24e-3)" "unprognostic (1.13e-2)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (4.53e-3)" "unprognostic (9.98e-3)" "unprognostic (9.21e-3)" "unprognostic (7.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.04e-2)" "unprognostic (3.54e-2)" "unprognostic (2.72e-2)" "unprognostic (2.17e-2)" "unprognostic (1.38e-1)" "unprognostic (3.93e-3)" 0.0 0.2 0.8 0.1 0.9 0.0 2.9 0.7 2.4 2.8 0.0 1.6 0.2 0.1 0.4 1.6 10.3 3.1 2.6 2.7 1.2 1.6 8.2 4.3 0.0 3.5 2.3 0.0 9.3 0.0 1.9 0.0 1.2 3.5 0.2 7.3 13.8 1.8 0.2 0.1 0.3 0.1 2.0 5.7 0.7 6.9 1.2 1.0 0.0 0.9 0.6 1.5 0.7 1.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 41.8 0.0 9.0 0.4 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.7 2.4 2.7 1.2 3.5 2.3 1.2 2.0 1.2 1.9 0.1 0.0 2.7 24.8 0.0 0.6 32.6 56.6 4.6 1.3 8.2 8.0 9.2 35.8 115.2 5.5 0.0 0.4 0.1 0.0 11.7 13.0 7.1 49.9 0.7 0.3 3.5 0.0 10.1 0.6 0.1 4.2 0.0 1.8 5.1 0.1 0.0 10.7 0.3 0.0 29.3 0.1 22.4 0.0 0.0 4.4 0.6 0.5 7.2 1.0 0.0 69.2 0.0 167.4 1.0 1.3 0.0 0.4 0.0 8.9 0.0 0.3 311.6 3.2 0.0 3.2 3.7 0.9 1.3 4.7 0.0 0.3 0.4 0.0 0.0 40.3 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSC1 CDHF1 ENSG00000134765 "Desmocollin 1" Q08554 18 31129236-31162856 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 228.8" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 166.5" "Group enriched" "Detected in some" 17 "head and neck cancer: 7.3;melanoma: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "naive CD4 T-cell: 2.7;naive CD8 T-cell: 2.6" "Lineage enriched" "Detected in single" 8 "T-cells: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA075379 Enhanced NA NA 27000000 "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 28: Keratinocytes - Keratinization" "HPA075379: AB_2732290" "unprognostic (1.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.48e-2)" "unprognostic (3.71e-2)" "unprognostic (8.19e-3)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.27e-1)" "unprognostic (1.78e-1)" "unprognostic (5.65e-6)" "unprognostic (5.08e-2)" "unprognostic (2.91e-1)" "unprognostic (6.99e-2)" "unprognostic (4.74e-5)" 0.2 0.0 0.0 0.1 0.0 0.2 9.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 228.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 2.7 2.6 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 14.1 0.3 0.0 2.2 0.9 0.1 0.4 29.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.4 0.0 0.0 3.6 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.5 166.5 0.4 0.6 0.0 0.0 0.3 DSG1 "CDHF4, DSG" ENSG00000134760 "Desmoglein 1" Q02413 18 31318160-31359246 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 564.4" "Group enriched" "Detected in some" 25 "Basal keratinocytes: 117.4;Suprabasal keratinocytes: 315.7" "Group enriched" "Detected in many" 10 "head and neck cancer: 57.0;melanoma: 16.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 23 "hTCEpi: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA022128, HPA074188" Enhanced NA NA 130000000 "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "HPA022128: AB_1847620, HPA074188: " "unprognostic (2.55e-2)" "unprognostic (8.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.13e-1)" "unprognostic (5.22e-1)" "unprognostic (1.81e-2)" "unprognostic (1.57e-2)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (2.19e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.99e-4)" 0.4 0.0 0.0 0.0 0.0 0.2 24.7 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 18.4 0.0 0.1 1.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.6 0.0 2.0 564.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 2.1 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.6 0.0 3.3 0.9 1.7 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.1 0.1 0.0 0.0 8.6 3.5 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.9 0.2 6.5 315.7 0.0 0.2 0.0 0.1 0.0 DSG4 "CDHF13, LAH" ENSG00000175065 "Desmoglein 4" Q86SJ6 18 31376777-31414912 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "skin 1: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Squamous epithelial cells: 1.0;Urothelial cells: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 133 "HaCaT: 37.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059456, HPA079244" Enhanced NA NA 320000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA059456: AB_2684025, HPA079244: " "unprognostic (9.86e-2)" "unprognostic (8.61e-2)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "unprognostic (5.55e-2)" "unprognostic (5.61e-2)" "unprognostic (2.11e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "unprognostic (2.14e-1)" "unprognostic (1.79e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.9 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.0 0.0 0.0 0.0 0.0 0.2 1.3 DSG3 CDHF6 ENSG00000134757 "Desmoglein 3" P32926 18 31447741-31478702 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 313.9;vagina: 119.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 197.6;Basal squamous epithelial cells: 101.9;Squamous epithelial cells: 470.6;Suprabasal keratinocytes: 206.4;Urothelial cells: 87.2" "Cancer enhanced" "Detected in many" "cervical cancer: 104.0;head and neck cancer: 183.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 53 "basophil: 8.2" "Lineage enriched" "Detected in single" 82 "granulocytes: 8.2" "Group enriched" "Detected in some" 7 "HaCaT: 204.4;hTCEpi: 494.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046864, HPA056863, CAB069880" Enhanced NA NA 190000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "CAB069880: AB_2093604, HPA046864: AB_2679846, HPA056863: AB_2683260" "unprognostic (5.76e-3)" "unprognostic (6.99e-2)" "unprognostic (7.67e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-2)" "unprognostic (4.08e-3)" "unprognostic (1.63e-1)" "unprognostic (3.21e-2)" "prognostic unfavorable (1.43e-5)" "unprognostic (8.26e-2)" "unprognostic (8.35e-7)" "unprognostic (8.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (9.90e-4)" 0.3 0.0 0.1 0.2 0.1 0.2 3.9 0.1 0.2 71.1 0.1 0.0 5.4 0.0 0.0 313.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.4 0.1 0.0 43.6 0.0 0.1 39.9 3.9 0.0 0.0 0.0 0.2 0.1 0.2 14.8 0.0 0.0 72.7 1.2 119.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 204.4 0.0 46.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 494.7 0.0 49.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.2 28.9 18.5 0.0 0.2 197.6 17.4 32.2 101.9 0.3 0.5 5.0 0.3 0.0 21.1 0.0 0.0 0.4 1.5 0.2 0.0 0.2 0.6 0.1 0.3 2.7 0.0 0.0 2.7 0.4 0.4 2.2 0.0 0.1 12.6 0.0 0.4 0.3 0.4 0.0 0.1 1.3 2.0 0.3 7.7 0.5 0.0 3.2 7.2 0.0 0.7 0.1 0.0 0.0 0.1 1.3 2.5 0.7 1.2 12.3 7.1 0.1 15.9 0.8 6.6 0.0 1.8 3.3 2.8 470.6 206.4 0.3 1.3 0.0 6.5 87.2 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 TTR "CTS, CTS1, HsT2651, PALB" ENSG00000118271 Transthyretin P02766 18 31557009-31598833 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Transport "Hormone, Thyroid hormone" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "choroid plexus: 142023.1" "Cell type enriched" "Detected in many" 30 "Hepatocytes: 23659.3" "Group enriched" "Detected in many" 28 "liver cancer: 928.2;pancreatic cancer: 666.0" "Group enriched" "Detected in all" 7 "cerebellum: 621.7;hippocampal formation: 1730.9;thalamus: 688.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 160.1;EFO-21: 39.6;Hep G2: 249.0;U-2 OS: 57.0" "Group enriched" "Detected in all" 5 "basal ganglia: 1538.3;hippocampal formation: 4891.0;pons and medulla: 5758.5;thalamus: 3400.4" "Region enhanced" "Detected in all" "medulla oblongata: 1381.8" "CAB002517, HPA002550, CAB062567, CAB073406" Supported Approved "Golgi apparatus" "Secreted to blood" NA NA 345000000000 99000000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "CAB002517: AB_563965, CAB062567: AB_2665620, CAB073406: , HPA002550: AB_1080419" "unprognostic (6.79e-3)" "unprognostic (3.38e-2)" "unprognostic (4.10e-1)" "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (8.15e-2)" "unprognostic (3.74e-2)" "unprognostic (9.66e-3)" "unprognostic (8.72e-2)" "unprognostic (1.23e-2)" "unprognostic (8.35e-3)" "unprognostic (5.26e-1)" "unprognostic (3.52e-2)" 4.2 0.6 148.5 0.5 56.7 9.6 0.4 621.7 83.7 2.0 142023.1 6.0 14.9 1.3 0.9 2.2 0.8 51.2 2.9 1730.9 37.3 18.4 21288.1 0.8 2.4 106.5 86.0 1.1 1785.1 186.8 6.0 2.7 27.1 1.6 4.5 80.1 1.8 0.4 1.1 15.6 6.8 0.3 12.3 3.8 49.8 2.3 688.2 1.1 1.3 0.0 0.1 2.3 0.6 133.9 1.6 0.4 0.6 0.5 0.8 0.1 1.0 0.8 0.3 0.0 0.0 160.1 0.0 2.9 39.6 0.5 0.6 0.4 0.0 0.3 0.0 5.9 0.8 5.2 1.8 249.0 0.4 11.2 1.0 0.1 0.1 0.1 0.0 0.7 0.0 0.3 2.8 0.4 0.0 0.5 0.4 0.7 0.6 4.5 0.3 0.3 7.4 0.2 0.3 1.6 0.9 1.1 5.8 0.0 0.2 1.7 0.6 0.2 1.7 2.4 57.0 0.5 4.3 1.0 2.6 17.6 0.7 4.3 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.0 0.0 148.5 56.7 621.7 83.7 1730.9 37.3 106.5 86.0 27.1 12.3 688.2 133.9 0.0 0.0 0.0 0.0 15.1 0.5 0.0 0.0 0.0 144.8 0.0 0.0 1.8 779.2 0.0 5.5 162.6 0.3 0.0 1.5 5.9 3.1 6.8 0.5 0.5 14.1 356.2 192.5 0.0 2.0 3.6 0.7 13.3 0.0 0.0 0.2 192.4 23659.3 2.4 26.9 0.1 19.6 0.0 313.7 0.0 8.7 0.3 1.2 0.0 0.0 0.0 24.9 0.0 0.0 0.0 130.5 5.2 0.0 0.0 0.2 1.3 26.9 0.0 56.0 0.0 0.0 0.3 3.3 1.1 0.0 0.1 4.0 10.9 0.0 1.7 0.0 B4GALT6 beta4GalT-VI ENSG00000118276 "Beta-1,4-galactosyltransferase 6" Q9UBX8 18 31622247-31685836 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.3" "Group enriched" "Detected in many" 5 "Bipolar cells: 101.3;Cone photoreceptor cells: 39.6;Excitatory neurons: 71.5;Inhibitory neurons: 103.7;Oligodendrocyte precursor cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "REH: 46.8;WM-115: 126.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020701, HPA058284" Approved "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "CAB020701: , HPA058284: AB_2683668" "unprognostic (3.79e-1)" "unprognostic (4.52e-1)" "unprognostic (6.54e-3)" "unprognostic (2.23e-4)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.31e-2)" "unprognostic (4.50e-2)" "unprognostic (5.18e-1)" "unprognostic (1.13e-1)" "prognostic favorable (5.65e-4)" "unprognostic (2.77e-1)" "prognostic favorable (6.40e-5)" "unprognostic (5.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (4.00e-1)" 3.8 12.1 2.0 2.7 3.1 4.5 1.3 8.4 10.2 1.1 1.6 3.4 7.2 1.9 2.0 4.5 2.3 6.6 3.6 5.2 4.8 3.2 2.6 1.1 1.4 1.2 2.7 3.8 1.9 7.4 1.8 2.6 2.1 5.1 3.3 25.3 4.5 3.8 3.5 2.1 9.2 1.7 0.9 1.6 3.0 5.2 5.0 6.3 2.0 6.4 1.1 2.4 0.6 0.4 6.0 13.1 23.7 13.4 0.4 0.5 8.7 1.9 0.0 0.4 0.2 25.2 5.0 9.4 10.9 2.3 28.4 2.4 12.7 10.7 1.5 37.1 11.2 12.4 1.3 0.6 2.6 22.6 2.0 2.4 2.3 3.6 7.5 12.0 13.3 21.9 1.8 0.0 0.1 3.6 25.4 1.7 10.2 7.1 7.2 46.8 4.2 0.0 2.9 12.3 12.6 19.7 8.7 1.5 15.7 19.1 1.7 6.8 13.4 26.5 5.5 0.0 14.9 8.9 0.5 19.4 10.8 20.2 126.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 1.2 0.1 0.0 0.0 0.1 2.0 3.1 8.4 10.2 5.2 4.8 1.2 2.7 2.1 0.9 5.0 0.4 3.2 0.0 0.5 12.7 0.0 5.5 0.9 1.5 12.0 101.3 2.0 1.8 7.6 0.0 1.2 1.8 39.6 0.6 5.9 2.6 3.9 1.3 6.1 1.2 6.2 3.6 3.0 4.6 71.5 1.1 0.2 3.0 2.6 1.3 0.0 4.5 4.2 2.1 0.7 13.5 103.7 2.1 0.0 0.6 1.2 3.5 1.2 1.5 0.0 9.4 0.3 4.6 6.2 81.4 5.3 2.3 3.1 2.6 1.1 2.3 5.4 1.2 0.6 5.6 0.0 1.2 1.6 1.0 9.7 3.7 1.7 0.3 1.4 1.4 3.8 0.7 SLC25A52 MCART2 ENSG00000141437 "Solute carrier family 25 member 52" Q3SY17 18 31759584-31760880 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 8.9" "Group enriched" "Detected in some" 4 "Early spermatids: 55.3;Late spermatids: 106.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046388, HPA058261" Uncertain Approved Mitochondria NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "HPA046388: AB_2679649, HPA058261: AB_2683657" "unprognostic (8.97e-2)" "unprognostic (4.85e-2)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (2.50e-1)" "unprognostic (9.05e-2)" "unprognostic (2.97e-2)" "unprognostic (1.30e-4)" "unprognostic (7.15e-3)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" "unprognostic (3.34e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAPPC8 "GSG1, HsT2706, KIAA1012, TRS85" ENSG00000153339 "Trafficking protein particle complex 8" Q9Y2L5 18 31829197-31953136 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 8.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041107 Approved Approved Microtubules,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Microtubules "HPA041107: AB_10793869" "unprognostic (4.04e-1)" "unprognostic (4.35e-2)" "unprognostic (2.62e-3)" "unprognostic (9.80e-2)" "unprognostic (8.18e-2)" "unprognostic (4.06e-2)" "unprognostic (9.68e-2)" "unprognostic (1.37e-1)" "unprognostic (7.67e-3)" "unprognostic (4.42e-2)" "unprognostic (3.00e-1)" "unprognostic (6.35e-3)" "prognostic favorable (1.85e-9)" "unprognostic (3.55e-2)" "unprognostic (7.03e-2)" "unprognostic (4.26e-1)" "unprognostic (2.92e-1)" 10.5 9.9 5.4 10.1 6.1 10.2 9.8 8.5 6.7 9.3 11.3 9.9 10.2 8.5 5.9 11.5 9.6 7.6 10.5 5.8 5.6 12.7 18.1 8.9 13.0 6.3 5.2 9.0 9.8 14.6 7.1 9.7 5.8 8.3 10.9 20.9 10.4 8.7 16.9 13.6 11.9 9.4 5.0 10.7 10.0 30.2 5.5 16.3 12.4 12.4 13.4 9.2 9.7 8.7 12.3 10.2 11.9 9.0 17.3 16.3 13.0 16.0 16.9 14.7 14.4 7.0 9.1 17.6 12.6 15.5 13.4 18.4 17.2 9.1 20.2 19.8 8.0 14.4 9.5 8.7 13.5 42.4 16.1 14.9 12.1 13.8 19.6 16.4 17.0 14.6 21.2 15.7 15.0 8.4 18.2 14.5 11.9 36.1 8.7 19.0 14.1 18.5 14.4 19.1 9.0 10.6 20.5 12.2 14.3 18.7 13.5 18.3 20.8 15.5 7.8 5.7 9.9 19.6 23.5 25.9 15.0 18.2 16.3 8.7 1.6 1.7 1.0 1.5 2.2 1.3 1.4 1.2 1.6 1.4 1.2 1.3 2.3 1.9 1.5 1.2 1.7 0.7 5.4 6.1 8.5 6.7 5.8 5.6 6.3 5.2 5.8 5.0 5.5 8.7 16.9 28.9 15.1 44.1 26.3 18.0 8.7 10.0 31.9 12.2 14.3 9.7 21.6 21.5 14.6 11.0 29.2 11.2 19.9 27.3 1.9 11.0 35.3 23.4 14.9 16.1 12.6 20.0 68.1 9.4 9.6 14.8 32.6 17.4 3.8 11.1 19.6 34.2 16.6 11.8 71.6 14.7 8.2 24.0 13.3 42.4 15.5 22.3 10.6 43.1 23.4 11.0 23.7 55.3 82.8 14.2 10.1 9.4 18.7 16.1 26.2 15.5 25.8 24.7 13.1 14.8 14.3 88.8 47.4 21.8 27.1 20.5 16.6 11.6 13.7 15.5 RNF125 FLJ20456 ENSG00000101695 "Ring finger protein 125" Q96EQ8 18 32018825-32073219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.4" "Cell type enhanced" "Detected in many" "dendritic cells: 169.6;Early spermatids: 90.7;NK-cells: 160.6;Oligodendrocytes: 64.3;T-cells: 114.8" "Cancer enhanced" "Detected in all" "testis cancer: 8.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 51.5;SK-MEL-30: 13.2;U-937: 11.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041514 Uncertain Supported "Nucleoli,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" Nucleoli "HPA041514: AB_10795596" "unprognostic (2.13e-2)" "unprognostic (2.05e-2)" "unprognostic (2.88e-1)" "unprognostic (3.93e-1)" "unprognostic (5.03e-1)" "unprognostic (4.50e-2)" "unprognostic (2.30e-3)" "unprognostic (6.15e-2)" "unprognostic (4.21e-2)" "unprognostic (3.24e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-2)" "prognostic unfavorable (4.06e-4)" "unprognostic (2.99e-1)" "unprognostic (4.12e-1)" "unprognostic (1.82e-1)" "unprognostic (7.07e-3)" 10.2 1.3 2.0 5.2 3.7 18.4 6.3 2.7 2.7 3.9 1.6 5.0 10.5 2.9 0.5 2.5 3.4 3.3 2.6 1.9 2.3 1.0 12.5 4.7 7.0 3.6 3.2 1.4 3.1 1.7 0.3 3.7 3.4 1.8 6.4 0.3 2.2 1.4 2.3 4.9 11.3 3.3 2.6 5.9 3.4 1.0 3.8 5.3 1.4 2.9 4.0 3.0 1.7 6.2 1.2 0.1 0.2 0.4 0.5 0.8 1.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 1.2 0.1 0.4 0.9 1.6 1.2 0.2 6.6 2.6 0.3 0.4 0.3 0.1 8.9 51.5 1.6 2.4 0.0 2.8 0.3 0.4 2.7 0.1 1.9 0.1 2.0 2.3 8.2 4.2 8.9 1.5 9.2 0.6 0.2 0.5 0.5 0.9 0.3 0.2 0.1 13.2 1.6 1.3 4.2 0.2 0.1 0.7 0.1 0.1 5.9 0.2 0.1 0.6 11.5 6.9 13.3 4.5 4.5 15.0 2.5 9.9 2.5 12.0 12.8 4.2 2.3 9.5 12.3 1.9 15.5 2.8 4.3 13.7 6.9 2.0 3.7 2.7 2.7 1.9 2.3 3.6 3.2 3.4 2.6 3.8 6.2 62.2 3.2 5.8 3.3 16.3 9.8 3.1 1.0 14.2 0.8 5.3 3.7 2.1 4.3 3.8 12.9 0.0 0.4 169.6 24.6 1.9 1.0 90.7 4.9 2.1 28.4 1.2 15.8 2.7 1.8 0.1 5.3 8.6 13.4 18.9 0.2 12.5 25.1 10.5 0.0 3.0 8.3 0.0 19.2 12.6 17.4 2.8 18.4 1.8 30.9 23.8 0.7 160.6 3.5 64.3 1.1 4.5 0.0 49.9 2.7 41.4 4.5 1.7 0.9 0.0 3.2 3.2 0.5 1.8 5.8 6.8 0.8 114.8 0.2 14.7 2.4 RNF138 "NARF, STRIN" ENSG00000134758 "Ring finger protein 138" Q8WVD3 18 32091874-32131561 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0;testis: 119.3" "Group enriched" "Detected in many" 15 "Early spermatids: 982.8;Late spermatids: 3827.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041101 Approved Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA041101: AB_10805837" "unprognostic (2.37e-2)" "unprognostic (4.63e-3)" "unprognostic (2.03e-3)" "unprognostic (1.01e-1)" "unprognostic (2.34e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.90e-2)" "unprognostic (6.90e-2)" "unprognostic (1.27e-2)" "unprognostic (6.15e-2)" "unprognostic (9.52e-3)" "unprognostic (2.77e-1)" "unprognostic (9.58e-2)" "unprognostic (1.90e-1)" 13.7 7.3 7.6 17.4 9.3 96.0 14.5 13.8 11.9 12.4 10.7 23.5 16.7 14.3 8.5 14.9 19.4 13.6 5.9 6.9 8.7 9.7 21.6 13.3 24.2 8.0 8.6 14.9 16.4 11.2 7.5 15.3 8.5 10.5 20.2 8.9 9.9 7.9 6.9 8.8 17.3 11.6 8.3 21.6 14.2 119.3 8.2 28.9 11.8 6.8 19.8 13.3 8.6 12.4 28.3 16.4 66.4 33.2 8.5 17.5 37.6 28.3 15.8 34.7 39.8 19.4 19.3 67.9 34.3 18.6 22.3 28.9 35.1 31.9 47.1 37.7 58.8 53.5 19.2 24.1 33.3 149.3 45.3 17.1 31.3 38.3 53.8 19.9 35.9 59.3 74.7 27.0 22.7 26.6 101.1 66.5 74.4 48.4 22.6 102.5 41.7 39.3 31.9 20.7 75.0 37.5 37.7 21.7 30.1 30.2 14.0 62.2 27.8 41.5 30.5 10.3 32.2 44.4 64.5 117.9 22.6 81.6 41.5 25.0 64.4 63.3 25.0 48.7 32.2 34.6 54.5 35.9 62.5 39.2 102.8 66.9 64.7 42.8 42.0 26.6 44.3 68.3 7.6 9.3 13.8 11.9 6.9 8.7 8.0 8.6 8.5 8.3 8.2 12.4 27.9 16.0 19.7 15.3 65.9 69.3 33.7 11.8 71.2 6.7 32.4 18.0 8.3 24.3 16.8 16.5 0.0 28.3 51.6 43.0 17.6 17.6 982.8 35.6 20.4 29.4 29.9 48.8 25.9 18.4 21.6 21.3 26.0 28.7 22.8 8.4 22.5 16.8 24.8 8.4 28.0 20.8 20.3 25.5 52.3 3827.9 29.5 34.7 26.6 23.4 27.1 9.9 20.6 22.6 36.4 12.9 23.9 22.2 32.4 32.7 16.4 14.5 23.0 5.2 32.9 23.1 26.0 158.1 128.3 51.4 52.1 8.9 59.3 9.9 29.9 37.5 GAREM1 "C18orf11, FAM59A, FLJ21610, GAREM" ENSG00000141441 "GRB2 associated regulator of MAPK1 subtype 1" Q9H706 18 32124877-32470882 "Predicted intracellular proteins" Mitogen "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 29.9" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 54.7;Urothelial cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 15.5;hTERT-HME1: 20.7;RT4: 19.6;SH-SY5Y: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040709, HPA042046" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "HPA040709: AB_2677090, HPA042046: AB_2677818" "unprognostic (9.52e-2)" "unprognostic (4.13e-3)" "unprognostic (2.67e-2)" "unprognostic (3.32e-3)" "unprognostic (3.62e-1)" "unprognostic (5.53e-3)" "unprognostic (1.87e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (5.59e-2)" "prognostic unfavorable (6.73e-5)" "unprognostic (1.45e-1)" "prognostic favorable (5.49e-6)" "unprognostic (2.36e-1)" "unprognostic (2.56e-3)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 5.0 6.0 5.1 1.8 7.0 7.2 4.5 7.5 7.2 4.2 0.3 4.8 4.4 2.3 2.1 8.2 2.7 2.9 5.1 9.5 7.1 11.2 6.7 3.2 0.6 9.8 6.5 2.7 29.9 0.6 3.3 2.8 8.5 3.0 3.7 6.2 7.9 2.9 5.9 11.0 4.2 2.2 7.6 2.0 8.5 3.4 6.7 0.4 2.0 2.8 1.7 7.2 7.4 11.7 1.2 1.8 1.8 0.4 4.9 4.0 4.5 0.5 0.0 0.0 0.0 0.4 2.7 3.4 2.6 0.1 2.0 4.0 2.7 5.0 0.0 1.0 1.9 0.0 3.8 1.3 3.0 0.3 0.3 4.4 15.5 0.2 20.7 0.2 0.2 2.0 0.2 0.9 2.2 2.8 1.0 0.2 2.0 9.9 1.0 1.2 7.4 5.6 8.0 19.6 6.3 18.0 4.1 6.5 0.1 2.3 0.9 3.4 0.2 1.3 1.3 0.0 0.6 2.3 0.4 0.9 2.3 0.0 1.5 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.6 0.3 0.5 1.0 1.1 0.0 1.9 0.0 0.0 5.1 7.0 7.5 7.2 9.5 7.1 9.8 6.5 8.5 7.6 6.7 11.7 11.9 9.6 42.6 0.0 0.2 0.0 37.6 0.0 3.4 34.2 6.9 5.1 0.0 11.5 8.6 25.8 4.2 20.4 0.0 10.7 1.9 11.8 14.8 19.8 8.7 2.0 3.6 0.0 0.0 13.3 2.6 14.3 27.0 41.7 3.8 0.9 0.4 8.8 1.7 42.1 0.0 8.4 0.0 4.0 0.0 3.4 1.8 1.9 0.0 0.0 0.6 34.9 0.0 0.0 0.0 9.3 5.7 5.3 0.5 54.7 19.8 23.4 4.4 7.4 0.0 29.8 6.5 3.9 7.5 13.7 0.0 33.5 0.9 1.7 7.6 114.2 MEP1B ENSG00000141434 "Meprin A subunit beta" Q16820 18 32185069-32220404 "Enzymes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "intestine: 363.9" "Cell type enriched" "Detected in some" 42 "Proximal enterocytes: 231.8" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA029119 Enhanced "Secreted to digestive system" NA NA 310000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 45: Enterocytes - Digestion" "HPA029119: AB_2672913" "unprognostic (1.33e-1)" "unprognostic (6.72e-2)" "unprognostic (2.79e-2)" "unprognostic (1.00e-1)" "unprognostic (3.50e-4)" "unprognostic (1.27e-1)" "unprognostic (1.74e-2)" "unprognostic (4.30e-1)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-4)" "unprognostic (4.74e-2)" "unprognostic (3.39e-1)" "unprognostic (2.71e-1)" "unprognostic (3.39e-2)" "unprognostic (3.75e-2)" 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.3 0.0 0.0 8.2 249.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 6.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 363.9 0.3 0.1 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 4.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.4 0.0 0.0 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.9 0.0 3.8 0.0 0.1 0.2 231.8 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 2.5 0.1 KLHL14 KIAA1384 ENSG00000197705 "Kelch like family member 14" Q9P2G3 18 32672673-32773023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 12.7;thyroid gland: 13.8" "Cell type enhanced" "Detected in some" "B-cells: 21.9;Inhibitory neurons: 9.8;Muller glia cells: 19.4;Plasma cells: 45.7" "Group enriched" "Detected in many" 10 "endometrial cancer: 6.8;ovarian cancer: 15.5;thyroid cancer: 7.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 90 "memory B-cell: 10.5;naive B-cell: 7.3" "Lineage enriched" "Detected in single" 106 "B-cells: 10.5" "Cell line enhanced" "Detected in some" "EFO-21: 3.1;Hep G2: 15.7;REH: 4.2;RPTEC TERT1: 8.4;SCLC-21H: 3.2;U-698: 4.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "hippocampal formation: 14.9;olfactory bulb: 8.1" HPA024777 Uncertain Supported "Actin filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Actin filaments" "HPA024777: AB_1852576" "unprognostic (3.93e-2)" "unprognostic (7.87e-2)" "unprognostic (7.09e-2)" "unprognostic (5.61e-3)" "unprognostic (1.87e-1)" "unprognostic (2.16e-6)" "unprognostic (2.14e-1)" "unprognostic (4.30e-2)" "unprognostic (4.81e-2)" "unprognostic (2.32e-3)" "unprognostic (2.32e-1)" "unprognostic (7.64e-2)" "unprognostic (8.91e-2)" "unprognostic (8.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (1.43e-2)" 0.5 0.2 0.2 1.8 0.3 2.4 0.5 0.0 0.6 2.9 0.0 0.2 0.2 1.7 1.0 0.2 6.6 0.3 0.1 0.2 0.3 5.0 0.0 0.3 7.1 1.4 2.3 0.3 0.0 6.9 0.3 0.8 0.7 1.4 0.2 4.7 0.4 12.7 0.0 0.1 2.0 0.8 0.8 8.7 0.2 1.0 0.2 0.3 13.8 0.0 5.3 0.6 0.5 0.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 3.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 15.7 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 4.2 1.3 0.0 8.4 0.0 3.2 0.4 0.0 0.0 0.7 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 0.0 0.6 0.2 0.3 1.4 2.3 0.7 0.8 0.2 0.1 1.3 0.0 0.0 0.3 21.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 7.3 0.0 0.0 0.1 0.0 3.9 0.0 4.5 7.1 0.3 2.0 0.0 0.0 1.6 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.7 0.0 0.1 1.7 9.8 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.0 0.0 19.4 0.0 1.5 0.2 0.0 0.0 0.0 45.7 0.0 0.5 1.1 0.0 0.8 0.0 0.0 0.1 0.7 0.6 0.0 0.3 0.0 0.2 4.7 0.1 0.0 CCDC178 "C18orf34, FLJ44050" ENSG00000166960 "Coiled-coil domain containing 178" Q5BJE1 18 32937402-33441101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 10.9;testis: 15.2" "Cell type enhanced" "Detected in some" "Adipocytes: 29.2;Early spermatids: 89.0;Late spermatids: 76.8;Spermatocytes: 49.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "HUVEC TERT2: 5.1;U-87 MG: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (9.88e-2)" "unprognostic (2.58e-1)" "unprognostic (2.75e-1)" "unprognostic (2.58e-3)" "unprognostic (2.92e-1)" "unprognostic (5.95e-4)" "unprognostic (4.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.94e-4)" "unprognostic (2.86e-1)" "unprognostic (1.42e-3)" "unprognostic (9.03e-3)" 10.9 0.3 0.2 0.2 0.3 0.0 7.8 0.0 0.4 2.7 0.1 0.8 0.5 1.3 2.2 0.6 1.5 2.5 0.5 0.2 0.3 2.8 0.1 0.7 0.2 0.4 0.6 4.0 0.1 0.0 0.6 0.0 0.2 3.5 0.5 0.1 0.5 2.0 0.3 0.7 0.6 1.5 0.4 7.6 0.6 15.2 0.1 0.1 0.8 0.0 0.6 2.1 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.4 0.2 0.3 0.4 0.6 0.2 0.4 0.1 0.2 29.2 0.0 0.0 0.3 0.0 0.4 0.4 0.0 2.2 0.0 0.1 0.4 0.3 0.0 0.0 1.8 0.0 0.0 0.1 0.0 9.8 0.0 89.0 0.6 0.3 12.8 0.0 0.0 7.9 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 76.8 1.8 0.2 0.0 2.8 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.7 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.2 49.4 16.3 0.1 0.3 0.0 0.0 6.1 0.0 0.0 ASXL3 KIAA1713 ENSG00000141431 "ASXL transcriptional regulator 3" Q9C0F0 18 33578219-33751195 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.2" "Group enriched" "Detected in many" 6 "Early spermatids: 52.5;Excitatory neurons: 125.1;Inhibitory neurons: 101.1;Late spermatids: 31.6;Oligodendrocyte precursor cells: 88.4;Oligodendrocytes: 62.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPMI-8226: 7.4;SCLC-21H: 2.8;SH-SY5Y: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039539, HPA040034" Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA039539: , HPA040034: " "unprognostic (2.05e-2)" "unprognostic (6.88e-2)" "unprognostic (2.91e-1)" "unprognostic (3.73e-4)" "unprognostic (1.30e-1)" "unprognostic (3.19e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (9.16e-2)" "unprognostic (5.35e-3)" "unprognostic (5.92e-2)" "unprognostic (2.47e-12)" "unprognostic (4.69e-2)" "unprognostic (2.32e-1)" "unprognostic (4.98e-3)" "unprognostic (1.67e-2)" 0.2 0.0 1.7 0.0 1.4 0.0 0.2 0.0 1.9 0.7 0.1 0.6 0.2 0.3 0.3 0.0 0.5 0.4 0.5 1.5 0.7 0.6 0.4 0.2 0.0 0.4 0.2 2.2 0.3 0.2 0.7 0.0 0.1 0.6 0.1 0.5 0.2 0.6 0.0 0.1 0.3 0.2 0.1 0.1 0.8 1.6 0.1 0.0 0.9 0.0 0.0 0.5 0.4 0.7 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.0 2.8 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 0.0 1.9 1.5 0.7 0.4 0.2 0.1 0.1 0.1 0.7 1.0 0.0 0.0 11.1 0.0 0.1 1.0 0.0 1.2 5.3 0.2 0.9 4.8 1.5 3.1 1.8 0.0 0.6 0.0 1.0 1.9 1.7 52.5 0.1 1.5 0.4 3.0 0.0 125.1 0.0 0.2 3.2 3.1 0.1 1.3 0.0 0.4 2.0 0.2 1.7 101.1 0.7 0.0 0.0 0.0 31.6 2.1 0.1 0.0 10.3 0.0 1.0 0.0 88.4 62.2 0.4 0.4 1.9 0.0 0.4 1.5 1.2 0.0 0.9 0.0 1.1 2.6 2.9 3.7 0.2 0.0 0.4 0.0 11.2 0.6 0.3 NOL4 "CT125, HRIHFB2255, NOLP" ENSG00000101746 "Nucleolar protein 4" O94818 18 33851100-34224952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.8;pituitary gland: 8.0;retina: 6.3;testis: 12.6" "Cell type enhanced" "Detected in some" "Astrocytes: 133.9;Early spermatids: 268.1;Excitatory neurons: 195.6;Inhibitory neurons: 207.7;Late spermatids: 95.7;Oligodendrocyte precursor cells: 326.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 36.0;SH-SY5Y: 9.5;U-698: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046740 Supported Nucleoplasm No NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA046740: AB_10960527" "unprognostic (7.86e-2)" "unprognostic (1.58e-1)" "unprognostic (3.61e-1)" "unprognostic (5.43e-7)" "unprognostic (5.76e-2)" "unprognostic (1.56e-2)" "unprognostic (7.19e-2)" "unprognostic (3.45e-1)" "unprognostic (1.12e-2)" "unprognostic (4.78e-2)" "unprognostic (3.52e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" "unprognostic (7.77e-2)" "unprognostic (7.71e-2)" 0.0 1.8 6.1 0.1 7.2 0.0 0.1 7.6 7.8 0.5 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.1 8.2 11.6 0.7 2.2 0.2 0.2 0.8 4.1 0.0 1.7 0.0 8.0 0.0 1.0 0.3 0.7 6.3 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.7 12.6 11.8 0.0 1.6 0.0 0.2 0.5 0.0 3.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.2 0.1 0.0 0.0 0.0 36.0 9.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 7.2 7.6 7.8 8.2 11.6 0.8 4.1 1.0 2.5 11.8 3.4 0.0 0.0 0.0 133.9 0.0 0.0 0.0 0.0 0.0 17.0 0.5 1.0 0.6 0.0 0.0 0.0 2.1 0.2 0.0 0.4 1.9 0.0 268.1 0.0 0.0 0.5 73.8 0.0 195.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.1 32.0 207.7 0.2 0.0 0.0 0.0 95.7 2.5 0.1 0.0 22.5 0.0 11.6 0.0 326.8 4.5 0.1 0.1 2.2 0.0 0.0 0.0 5.3 0.0 2.1 0.0 0.0 0.0 10.9 2.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 MAPRE2 "EB1, EB2, RP1" ENSG00000166974 "Microtubule associated protein RP/EB family member 2" Q15555 18 34976928-35143470 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 163.3;Oligodendrocytes: 435.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016738, HPA016739" Enhanced Uncertain Nucleoplasm NA NA 13000000 "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA016738: AB_1853571, HPA016739: AB_1853570" "unprognostic (2.01e-1)" "unprognostic (3.48e-1)" "unprognostic (2.55e-2)" "unprognostic (5.30e-3)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (8.53e-2)" "unprognostic (1.09e-2)" "unprognostic (2.29e-1)" "unprognostic (2.93e-2)" "unprognostic (5.40e-2)" "unprognostic (2.22e-3)" "unprognostic (5.83e-2)" "unprognostic (1.34e-1)" "unprognostic (3.16e-2)" "unprognostic (3.99e-3)" 22.4 58.7 54.2 29.1 65.2 22.1 16.6 58.5 89.4 19.3 1.9 24.5 15.0 14.0 18.9 17.4 12.7 41.1 89.1 68.8 56.9 18.4 33.4 27.2 35.8 74.0 61.0 24.9 12.8 19.2 16.3 28.3 70.6 16.1 24.6 49.1 20.2 17.2 50.4 26.1 19.6 23.8 70.0 27.8 30.6 6.4 68.2 74.4 21.7 91.9 32.6 27.2 14.4 109.0 0.8 26.3 28.9 15.4 17.1 15.9 2.0 18.7 44.7 22.3 37.2 2.0 9.9 87.8 21.3 41.1 23.5 35.0 22.8 15.2 39.8 51.5 21.3 88.9 26.9 52.8 12.6 49.5 72.3 19.6 4.0 30.4 10.5 21.2 124.0 61.4 28.3 37.7 28.8 1.7 104.6 16.4 22.5 28.8 5.2 41.6 35.2 20.0 11.9 0.4 35.9 23.9 14.0 0.7 15.5 27.2 3.2 29.0 21.0 24.1 13.4 14.2 12.7 19.9 50.8 50.8 41.4 65.1 38.2 69.0 30.0 46.7 63.8 37.7 49.5 60.8 44.4 58.3 33.4 55.5 50.6 61.5 21.5 74.4 51.6 47.3 52.9 76.9 54.2 65.2 58.5 89.4 68.8 56.9 74.0 61.0 70.6 70.0 68.2 109.0 27.0 22.4 18.3 104.8 73.0 23.7 5.1 2.0 38.1 109.6 18.9 19.7 105.6 12.8 4.8 5.5 25.0 0.6 107.9 13.3 5.9 9.8 12.4 11.9 12.6 29.4 29.3 25.0 163.3 12.8 9.7 28.5 42.3 14.6 27.3 4.6 33.5 26.1 26.1 52.2 141.7 25.8 4.1 44.7 38.3 6.8 19.3 44.6 30.2 70.3 17.1 40.3 52.5 97.5 435.9 10.1 15.6 21.1 31.6 2.9 12.0 5.1 6.5 12.5 78.9 25.4 74.9 1.9 10.6 9.1 27.6 0.8 76.1 15.0 11.1 3.5 ZNF397 "MGC13250, ZNF47, ZSCAN15" ENSG00000186812 "Zinc finger protein 397" Q8NF99 18 35241030-35267133 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026087 Uncertain Approved "Nucleoli,Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli, Plasma membrane, Cytosol" Microtubules "HPA026087: AB_1859243" "unprognostic (1.97e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "unprognostic (3.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.74e-3)" "unprognostic (1.45e-2)" "unprognostic (1.48e-2)" "unprognostic (3.28e-2)" "prognostic favorable (9.44e-4)" "unprognostic (2.46e-2)" "unprognostic (2.17e-3)" "unprognostic (3.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.09e-3)" 12.9 13.4 17.6 14.4 23.4 5.0 16.1 19.1 20.0 13.5 14.9 12.8 10.6 15.7 12.4 9.8 11.7 10.1 10.5 16.4 20.7 11.3 10.6 10.4 16.2 20.5 20.9 17.8 12.4 14.8 12.0 11.9 20.1 13.9 13.9 25.0 12.4 12.1 11.7 13.6 12.6 11.5 15.4 16.1 13.3 9.9 20.3 13.1 15.7 11.0 15.8 11.9 11.8 34.4 4.2 7.9 18.7 17.1 20.3 17.0 8.9 8.4 8.3 4.1 5.4 3.0 5.7 21.2 7.4 6.7 5.6 11.1 12.2 9.2 5.7 13.5 7.5 0.9 11.7 8.6 6.7 10.3 7.4 7.7 12.1 4.9 14.1 14.6 2.6 16.1 12.7 14.4 10.7 9.1 17.4 7.8 16.1 3.2 3.2 18.2 5.4 15.1 8.4 11.0 20.2 17.4 13.7 7.2 8.2 16.2 12.5 7.6 4.2 13.6 7.6 4.6 3.8 23.2 9.3 11.9 12.0 7.1 13.1 10.1 4.6 8.3 5.7 7.5 4.1 10.6 5.3 4.7 3.3 11.3 7.8 5.4 11.0 4.7 9.4 7.5 3.0 2.2 17.6 23.4 19.1 20.0 16.4 20.7 20.5 20.9 20.1 15.4 20.3 34.4 15.5 35.3 21.0 24.5 35.3 4.1 19.4 8.0 10.2 51.0 11.8 10.4 16.4 15.7 17.3 14.7 35.5 22.6 15.8 14.1 13.7 18.7 66.0 10.8 20.4 17.6 31.0 20.4 17.4 10.9 13.4 18.4 12.8 8.9 11.4 31.7 31.1 12.6 10.8 33.7 19.5 11.5 12.2 20.5 5.4 49.6 18.6 11.8 8.8 23.4 20.3 24.6 15.5 30.2 94.1 10.7 18.3 22.6 6.1 15.8 24.3 11.4 16.4 46.1 32.9 25.3 16.6 29.7 23.4 7.8 4.5 14.6 13.9 22.1 16.1 11.1 ZSCAN30 "ZNF397OS, ZNF917" ENSG00000186814 "Zinc finger and SCAN domain containing 30" Q86W11 18 35251058-35290245 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007289 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA007289: AB_1079726" "unprognostic (6.02e-3)" "unprognostic (1.15e-1)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (8.94e-2)" "unprognostic (3.56e-3)" "unprognostic (7.02e-3)" "unprognostic (3.05e-3)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (3.05e-3)" "unprognostic (2.78e-3)" "unprognostic (8.27e-3)" "unprognostic (1.15e-1)" "unprognostic (8.44e-3)" "unprognostic (8.75e-2)" "unprognostic (1.36e-1)" 9.2 14.1 12.1 7.9 14.4 7.5 10.1 26.1 16.2 12.3 9.3 11.2 8.6 10.7 10.9 7.1 11.7 7.3 17.5 11.0 15.8 12.1 8.4 9.2 11.0 12.9 9.6 11.1 10.7 13.1 16.7 8.1 12.6 11.3 6.8 28.0 9.3 7.0 16.9 9.9 11.2 7.6 7.7 12.9 9.3 10.0 14.5 11.1 14.6 8.7 7.9 9.7 9.1 26.9 6.2 1.7 13.4 18.2 9.1 17.8 9.3 11.9 15.9 6.7 13.1 5.1 7.6 11.3 7.7 12.5 11.5 4.1 6.5 12.4 18.0 11.5 3.7 7.1 8.9 3.6 9.3 5.9 6.8 11.6 9.6 17.9 15.5 17.5 13.2 15.7 12.1 12.8 18.0 2.8 9.1 10.5 8.9 1.8 5.7 13.6 4.6 8.4 10.4 4.2 19.4 9.9 11.7 3.7 4.8 14.1 5.8 8.3 15.5 24.6 5.2 3.8 4.6 23.4 10.7 10.0 18.4 6.8 13.9 1.4 0.6 2.3 2.1 0.8 1.3 2.5 2.0 1.2 1.1 3.3 2.3 2.6 2.3 2.0 1.0 2.6 2.0 1.2 12.1 14.4 26.1 16.2 11.0 15.8 12.9 9.6 12.6 7.7 14.5 26.9 8.4 9.6 8.7 22.2 7.5 1.8 2.0 3.2 13.6 30.5 4.8 5.5 15.5 10.0 9.1 1.8 20.9 3.3 6.4 3.4 5.9 5.2 9.3 7.0 11.9 10.7 7.2 7.8 21.8 3.4 1.5 6.0 7.7 6.5 8.8 18.8 10.0 5.2 2.6 20.2 18.4 4.0 2.0 4.7 1.7 9.0 5.9 3.3 0.0 23.4 2.3 12.2 7.2 26.2 52.1 3.1 4.0 7.9 3.3 2.0 5.9 4.5 6.2 19.3 0.0 10.3 6.3 13.5 5.3 4.2 1.0 1.8 5.3 15.4 3.1 1.6 ZNF24 "KOX17, Zfp191, ZNF191, ZSCAN3" ENSG00000172466 "Zinc finger protein 24" P17028 18 35332227-35345482 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024062, CAB025642" Supported Supported Nucleoplasm NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Nucleoplasm "CAB025642: , HPA024062: AB_1859150" "unprognostic (1.19e-1)" "unprognostic (3.25e-1)" "unprognostic (1.16e-3)" "unprognostic (2.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.49e-2)" "unprognostic (3.12e-2)" "unprognostic (2.79e-2)" "unprognostic (6.01e-2)" "unprognostic (7.69e-2)" "unprognostic (5.68e-2)" "unprognostic (2.44e-2)" "prognostic favorable (1.44e-4)" "unprognostic (5.25e-2)" "unprognostic (1.74e-2)" "unprognostic (9.27e-2)" "unprognostic (5.30e-3)" 19.4 21.9 32.1 22.4 40.0 25.0 35.3 34.9 34.8 21.6 29.7 19.7 20.5 23.8 22.2 17.8 18.2 18.1 20.9 28.7 33.1 23.8 30.9 21.5 28.8 36.4 36.8 26.1 25.8 32.3 12.5 23.4 37.3 25.5 21.4 38.0 23.7 18.3 23.7 15.4 21.4 18.2 33.4 25.6 25.1 19.9 33.4 34.0 33.3 27.6 26.4 19.2 12.6 54.4 19.3 19.1 60.0 31.5 24.9 26.7 16.9 25.9 29.1 31.3 35.7 12.4 15.5 43.7 28.4 21.7 25.0 34.8 44.7 24.3 53.5 40.1 24.3 31.3 40.2 26.7 26.2 66.9 48.6 22.6 41.0 28.0 30.2 36.0 30.2 27.2 48.2 27.6 32.8 22.8 51.3 28.5 31.2 12.8 12.8 38.0 38.8 35.1 31.5 44.0 51.0 43.7 31.6 29.2 54.7 31.0 27.4 50.3 25.7 44.8 20.1 10.8 26.1 69.7 60.6 44.4 25.0 27.0 41.8 30.2 21.0 24.8 24.4 20.3 23.5 30.5 24.1 20.8 19.3 30.2 23.0 21.4 40.9 22.4 30.3 29.7 20.0 15.2 32.1 40.0 34.9 34.8 28.7 33.1 36.4 36.8 37.3 33.4 33.4 54.4 49.0 57.7 63.0 30.0 66.1 32.9 65.9 44.2 29.0 57.2 62.6 55.4 46.9 52.9 60.7 25.8 43.8 41.4 52.7 37.7 27.4 46.4 126.1 47.6 37.6 50.2 55.6 43.1 26.9 41.1 33.6 47.5 29.6 41.1 43.6 40.0 42.8 48.3 35.3 79.1 26.4 39.2 44.7 38.2 25.4 33.8 54.3 38.6 23.2 33.7 43.1 101.3 56.7 33.2 71.7 42.3 37.8 50.0 34.0 67.2 29.8 30.4 59.1 85.5 46.0 50.1 53.9 59.0 51.6 32.7 32.5 70.7 45.6 50.9 32.2 76.5 ZNF396 "FLJ31213, ZSCAN14" ENSG00000186496 "Zinc finger protein 396" Q96N95 18 35366694-35377337 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 14.4;Late spermatids: 12.0;Respiratory ciliated cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006686 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "HPA006686: AB_1080710" "unprognostic (3.28e-2)" "unprognostic (2.07e-2)" "unprognostic (1.24e-2)" "unprognostic (9.58e-3)" "unprognostic (2.27e-1)" "unprognostic (2.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (5.74e-2)" "unprognostic (1.88e-2)" "unprognostic (5.12e-2)" "unprognostic (6.72e-2)" "unprognostic (5.75e-7)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (3.91e-2)" 1.6 2.6 2.2 1.5 3.1 2.4 3.4 3.8 3.2 3.0 4.9 1.6 1.1 1.6 2.7 1.0 4.9 2.4 0.9 2.1 2.5 3.6 1.5 2.0 1.3 3.0 3.2 1.7 3.0 4.4 3.3 0.7 2.6 2.3 1.8 4.0 3.3 2.1 1.4 1.6 2.2 1.2 2.4 1.5 2.7 5.6 3.0 1.5 5.5 1.0 1.6 1.6 1.0 3.3 0.3 2.2 1.9 2.0 1.3 0.8 1.7 0.4 1.1 0.9 1.8 0.7 1.3 0.1 1.0 1.0 1.2 0.2 1.0 1.0 1.3 0.8 1.3 0.8 1.8 1.7 2.2 0.4 1.4 1.1 1.1 0.5 0.5 3.0 1.5 2.7 0.6 2.4 0.7 2.3 0.6 1.0 0.5 0.6 0.4 0.4 0.0 0.7 2.2 1.8 1.0 3.4 1.4 1.1 2.3 1.6 3.3 1.9 0.1 0.3 0.4 0.8 0.6 4.6 1.8 0.1 1.7 0.1 1.5 8.9 1.4 2.6 1.5 0.8 0.9 0.6 1.1 0.9 1.2 1.3 1.6 1.1 5.8 1.5 1.1 1.6 0.5 0.6 2.2 3.1 3.8 3.2 2.1 2.5 3.0 3.2 2.6 2.4 3.0 3.3 0.6 6.4 5.3 1.6 0.2 0.4 1.0 1.1 0.6 2.7 1.9 1.8 0.8 2.8 2.9 0.0 0.0 0.4 0.5 1.2 0.0 1.8 14.4 7.1 1.9 1.0 0.0 0.4 1.2 2.0 0.3 2.3 1.5 1.4 2.5 0.8 1.1 0.7 0.7 3.3 1.5 1.1 6.1 0.8 1.0 12.0 0.9 1.0 0.0 2.8 1.6 4.5 0.0 3.0 2.6 1.4 1.9 1.2 0.1 0.7 1.1 3.0 19.0 5.9 6.6 2.9 2.2 8.4 1.6 0.8 0.1 0.1 0.8 1.8 0.9 0.8 AC007998.2 ENSG00000267140 "Novel protein" 18 35443871-35497940 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8" "Cell type enhanced" "Detected in single" "Endothelial cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 63 "HUVEC TERT2: 257.0" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "unprognostic (6.67e-3)" "unprognostic (5.32e-2)" "unprognostic (2.01e-1)" "unprognostic (3.51e-2)" "unprognostic (1.48e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (7.77e-2)" "unprognostic (4.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.61e-1)" 1.8 0.2 0.1 1.8 0.2 0.5 3.3 0.1 0.2 2.6 0.2 0.9 0.5 0.8 0.2 0.9 3.2 1.7 0.6 0.2 0.2 0.5 0.1 1.5 4.8 0.2 0.2 0.3 0.5 0.1 0.0 0.5 0.2 0.1 0.8 0.0 0.1 0.7 0.9 0.2 0.6 1.7 0.1 0.8 0.5 0.2 0.2 0.4 1.8 1.4 1.4 1.6 0.1 0.2 0.6 0.4 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.8 0.6 1.1 0.0 0.6 0.7 0.2 0.0 1.3 0.9 0.0 0.2 0.2 1.2 4.1 0.3 2.4 0.5 0.6 1.6 0.0 0.5 0.2 0.3 0.7 257.0 0.0 0.1 0.1 0.0 0.3 0.1 1.1 0.1 0.0 0.0 0.1 0.2 1.6 0.2 0.5 1.1 0.2 0.3 0.7 0.0 0.9 0.0 0.0 0.7 0.6 0.1 0.0 0.8 0.5 0.4 2.0 0.3 1.1 0.2 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 INO80C "C18orf37, FLJ38183, hIes6, IES6" ENSG00000153391 "INO80 complex subunit C" Q6PI98 18 35452230-35497979 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 184.7;Pancreatic endocrine cells: 165.1;Spermatocytes: 209.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049060 Approved Approved "Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center" "HPA049060: AB_2680617" "unprognostic (3.40e-1)" "prognostic favorable (3.58e-4)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.62e-5)" "unprognostic (5.56e-2)" "unprognostic (9.68e-2)" "unprognostic (1.72e-3)" "unprognostic (2.03e-1)" "unprognostic (3.32e-3)" "unprognostic (2.08e-3)" "unprognostic (2.61e-1)" "unprognostic (6.94e-3)" "unprognostic (1.18e-1)" "unprognostic (5.82e-2)" "unprognostic (1.44e-2)" "unprognostic (5.14e-3)" "unprognostic (5.38e-2)" 18.0 17.4 23.2 14.5 24.4 46.2 16.0 24.9 23.7 18.4 30.9 21.1 18.4 12.0 13.6 45.7 13.7 13.0 25.6 23.2 31.1 21.8 19.2 17.5 26.2 22.2 23.1 9.8 13.3 8.0 29.2 20.7 24.2 13.9 21.8 33.6 20.7 9.2 42.4 40.5 18.6 11.0 21.0 31.2 30.4 92.2 31.5 21.9 15.2 30.7 29.2 21.4 20.8 23.6 46.5 30.1 27.1 14.9 9.5 23.6 29.7 17.5 13.2 27.3 36.5 37.5 38.7 77.4 36.6 11.9 41.6 31.3 52.4 112.7 24.8 22.9 28.3 97.8 36.0 40.7 21.0 57.4 60.1 10.7 31.9 70.7 37.9 33.7 80.0 32.3 30.4 27.8 44.7 49.3 36.4 48.5 34.6 32.2 18.0 28.5 19.2 26.5 58.4 58.9 37.3 25.8 27.9 31.6 23.4 41.8 31.5 46.1 51.5 30.9 13.5 24.0 32.3 24.1 28.4 137.8 25.2 52.7 19.2 21.3 14.8 35.6 12.3 20.6 12.2 24.9 17.0 16.3 22.2 17.8 17.2 14.2 23.0 12.4 18.3 33.5 21.7 11.8 23.2 24.4 24.9 23.7 23.2 31.1 22.2 23.1 24.2 21.0 31.5 23.6 40.2 6.4 10.1 5.9 19.5 24.0 22.1 72.3 18.8 4.4 16.3 15.2 17.8 18.6 31.6 12.9 4.2 59.8 14.0 81.4 31.3 43.9 184.7 16.7 6.6 30.5 15.0 29.0 15.6 40.0 105.1 14.1 41.8 14.4 20.3 9.0 22.1 16.6 52.2 5.0 11.3 20.4 36.7 17.9 15.0 49.6 6.2 16.4 23.2 6.5 14.1 22.8 14.4 9.0 10.9 165.1 76.0 7.2 26.4 20.7 48.8 80.9 31.5 14.1 0.0 18.5 15.6 209.0 40.3 35.3 39.9 73.2 16.4 11.9 35.9 34.7 GALNT1 GalNAc-T1 ENSG00000141429 "Polypeptide N-acetylgalactosaminyltransferase 1" Q10472 18 35581117-35711834 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 331.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012628 Uncertain "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA012628: AB_1849439" "unprognostic (9.81e-2)" "unprognostic (1.01e-1)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" "unprognostic (2.08e-1)" "unprognostic (2.83e-2)" "unprognostic (1.96e-2)" "unprognostic (7.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.51e-2)" "unprognostic (3.00e-2)" "unprognostic (1.00e-1)" "unprognostic (3.47e-2)" "unprognostic (4.38e-2)" "unprognostic (2.74e-2)" "unprognostic (1.07e-2)" "unprognostic (8.60e-2)" 28.9 20.6 11.9 27.4 12.1 26.0 37.2 12.3 14.2 26.5 15.1 42.8 42.9 19.4 19.7 57.6 15.9 28.9 23.8 10.9 14.4 17.4 45.9 23.3 33.5 13.1 13.2 16.9 24.6 12.2 13.5 52.0 13.5 25.4 41.1 17.1 46.8 18.0 29.0 52.4 49.3 22.7 13.1 25.4 27.1 16.9 13.1 18.6 30.0 37.3 40.8 70.5 27.0 13.9 32.5 34.9 40.5 37.6 78.5 74.0 53.4 33.2 35.4 30.3 27.4 21.0 61.9 38.3 34.9 36.0 28.7 24.4 20.2 63.8 48.1 45.0 18.5 48.7 62.8 48.8 39.2 106.6 62.1 50.7 59.7 47.6 52.1 90.1 331.4 30.8 14.8 49.3 118.9 26.1 31.6 40.5 41.6 33.5 16.4 38.9 53.0 18.5 124.8 148.9 21.8 42.9 59.4 43.0 36.2 77.1 32.9 82.8 116.3 55.7 22.5 37.0 37.1 70.1 35.7 72.5 39.1 72.1 29.5 7.2 3.4 7.6 3.2 4.5 3.6 4.1 2.2 2.9 4.0 2.4 2.0 3.0 4.3 4.6 6.6 4.4 2.5 1.4 11.9 12.1 12.3 14.2 10.9 14.4 13.1 13.2 13.5 13.1 13.1 13.9 85.6 80.1 44.1 35.9 33.4 29.8 28.4 28.8 22.2 31.3 77.2 43.8 43.3 48.6 39.9 16.5 12.5 31.0 44.8 109.1 7.9 42.6 1.4 77.6 44.7 41.7 38.9 30.9 57.5 39.9 92.7 49.8 26.0 73.0 20.3 51.7 35.7 71.3 77.9 85.8 56.3 59.0 16.2 58.8 37.1 2.9 19.0 56.7 19.6 57.1 41.3 105.9 28.8 54.3 56.8 58.5 51.4 18.0 36.7 54.4 76.8 22.0 33.5 28.5 13.1 55.2 28.7 6.5 12.2 26.3 82.1 33.2 33.7 50.3 85.3 52.8 C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.2;Late spermatids: 76.3;Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" 16.4 18.2 15.2 12.8 15.7 71.9 20.5 18.6 19.7 13.6 14.2 15.1 16.2 15.3 18.4 14.7 14.9 12.3 18.3 15.4 15.2 15.1 16.9 12.2 21.8 15.0 15.0 17.0 23.2 17.9 12.9 14.6 15.0 14.4 13.1 19.2 19.3 12.9 34.1 16.3 15.2 13.0 15.6 18.1 19.8 35.8 15.4 21.9 14.0 26.4 18.8 16.3 12.3 16.5 24.9 17.2 35.3 27.0 25.4 36.2 25.9 34.3 34.9 42.3 44.7 15.8 17.8 22.4 33.7 27.4 26.9 26.2 28.2 28.8 45.7 33.4 30.4 22.5 21.2 35.5 35.3 65.4 26.3 37.9 46.7 38.2 39.3 36.8 37.0 30.6 39.7 34.0 29.4 29.5 42.4 48.0 30.4 11.6 18.9 28.0 30.7 43.0 29.2 29.5 25.5 36.0 25.4 18.8 58.3 32.7 28.2 31.2 24.3 43.3 19.1 15.8 31.0 43.2 41.4 46.0 21.4 37.3 22.1 97.5 28.8 34.2 24.5 30.7 24.2 34.7 25.9 23.2 27.1 30.9 19.8 25.9 28.0 28.8 30.0 26.6 41.5 19.8 15.2 15.7 18.6 19.7 15.4 15.2 15.0 15.0 15.0 15.6 15.4 16.5 9.6 19.2 6.1 3.9 13.7 11.9 8.9 17.4 18.2 9.6 13.1 16.5 12.7 10.0 12.1 1.8 6.2 19.0 23.0 10.4 11.7 20.2 145.2 13.7 14.7 10.8 7.2 12.4 5.5 28.8 32.0 12.4 8.6 14.4 14.0 12.9 10.0 9.6 21.3 8.4 6.0 12.9 16.2 20.1 10.3 76.3 22.4 14.4 12.4 5.6 24.4 13.1 20.6 4.5 5.1 20.0 14.0 17.0 13.5 11.7 17.8 20.1 5.1 12.1 0.0 14.1 11.3 124.0 35.9 12.8 12.4 13.1 13.6 17.3 15.9 9.3 RPRD1A "FLJ10656, HsT3101, P15RS" ENSG00000141425 "Regulation of nuclear pre-mRNA domain containing 1A" Q96P16 18 35984387-36067576 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 233.0;Late spermatids: 362.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040602 Supported Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA040602: AB_10673137" "unprognostic (2.06e-1)" "unprognostic (9.14e-2)" "unprognostic (1.41e-3)" "unprognostic (2.22e-1)" "unprognostic (9.92e-3)" "unprognostic (2.69e-1)" "unprognostic (2.93e-3)" "unprognostic (1.68e-1)" "unprognostic (2.80e-2)" "unprognostic (3.94e-3)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (5.50e-3)" "unprognostic (7.95e-2)" "unprognostic (6.78e-3)" "unprognostic (1.49e-1)" "unprognostic (4.30e-1)" 23.3 34.8 40.6 16.4 44.4 11.3 24.7 40.7 59.9 21.1 34.6 29.6 19.0 25.7 115.2 23.6 25.3 18.5 29.1 45.5 43.2 26.7 21.8 19.2 19.5 39.5 40.3 24.1 23.4 26.1 27.8 17.8 40.0 29.6 20.5 41.5 28.3 28.9 54.7 20.9 19.0 21.3 41.4 22.3 21.3 28.0 42.6 19.9 32.1 46.5 19.3 27.6 20.0 44.4 31.6 34.1 57.0 60.8 30.6 35.8 35.5 55.6 54.5 31.7 44.5 9.4 34.2 44.1 57.2 40.7 16.9 51.2 64.1 56.3 44.7 39.2 36.6 46.9 48.9 37.0 53.9 78.9 24.3 27.6 73.7 30.2 85.4 39.8 46.0 51.5 42.8 46.7 41.1 39.3 42.4 33.3 45.9 16.2 24.4 34.7 18.3 70.8 48.4 66.9 99.1 83.4 46.5 25.7 48.3 46.2 35.2 55.9 56.4 33.0 20.6 17.7 46.0 52.5 77.6 45.0 33.6 64.1 33.9 0.7 4.7 2.2 2.9 6.3 4.4 5.0 4.0 3.4 7.8 5.4 5.0 4.0 3.5 7.0 4.2 5.4 2.3 3.3 40.6 44.4 40.7 59.9 45.5 43.2 39.5 40.3 40.0 41.4 42.6 44.4 19.0 32.1 20.7 54.9 40.6 34.4 35.9 23.6 54.7 49.6 29.9 22.2 39.4 17.2 21.0 35.0 31.3 17.1 28.7 13.6 27.4 21.0 233.0 36.3 30.2 23.1 28.8 24.6 105.0 19.9 17.6 19.0 25.0 52.5 13.3 50.7 20.7 29.3 9.8 37.0 91.0 16.7 22.4 20.1 24.2 362.4 22.1 18.8 30.2 58.1 18.1 32.2 18.6 84.9 98.5 20.4 25.2 23.0 33.1 41.5 17.8 26.2 20.3 50.8 13.1 26.1 27.0 39.5 42.2 45.2 38.2 14.6 21.9 51.9 22.2 38.2 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 ELP2 "FLJ10879, STATIP1, StIP" ENSG00000134759 "Elongator acetyltransferase complex subunit 2" Q6IA86 18 36129444-36180557 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation, tRNA processing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002996, CAB020835" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB020835: , HPA002996: AB_1857552" "unprognostic (5.51e-2)" "unprognostic (1.29e-1)" "prognostic favorable (5.41e-4)" "unprognostic (6.66e-3)" "unprognostic (4.33e-2)" "unprognostic (4.54e-1)" "unprognostic (2.23e-1)" "unprognostic (5.89e-2)" "unprognostic (1.92e-1)" "unprognostic (6.74e-3)" "unprognostic (7.31e-3)" "unprognostic (7.07e-2)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (3.05e-2)" "unprognostic (1.14e-1)" "unprognostic (8.97e-2)" 17.7 20.7 12.1 12.3 13.2 13.2 35.3 12.4 11.9 23.5 12.3 19.1 15.2 27.3 31.0 15.9 28.8 20.3 23.6 11.4 14.2 18.9 46.2 16.6 19.9 12.1 12.1 48.6 24.4 24.8 20.7 20.8 12.6 29.4 16.2 21.2 19.1 26.3 32.4 21.5 14.0 22.5 12.2 16.7 16.5 22.2 13.4 23.6 21.8 32.3 23.3 22.5 16.9 16.0 23.7 16.7 30.8 27.8 42.7 63.9 33.9 47.9 69.3 39.6 52.5 17.6 21.5 49.6 32.6 40.4 26.5 32.9 39.7 35.8 55.8 22.6 21.1 19.2 27.4 31.0 46.6 63.0 19.6 52.3 40.2 39.4 63.6 59.5 45.0 33.8 32.9 25.4 42.4 28.4 30.6 27.0 36.7 18.2 12.6 48.7 37.0 34.9 35.7 54.4 24.2 46.3 45.1 17.6 73.0 44.0 22.5 31.2 26.8 35.6 20.5 13.2 24.8 30.4 25.6 46.2 30.0 33.2 31.3 22.0 12.1 10.0 12.6 17.6 17.9 20.0 17.0 15.0 17.6 16.3 21.5 18.9 2.2 22.2 24.8 17.5 18.4 14.0 12.1 13.2 12.4 11.9 11.4 14.2 12.1 12.1 12.6 12.2 13.4 16.0 25.0 48.1 28.8 34.3 46.3 32.9 49.4 33.8 39.9 50.1 42.1 28.6 48.5 22.8 29.2 35.0 43.8 39.5 45.9 10.9 29.4 26.4 55.0 29.9 33.1 29.4 24.7 21.7 61.7 22.2 42.3 39.2 17.3 29.5 36.7 39.9 24.7 75.3 22.8 33.7 60.7 20.3 20.3 28.0 24.8 90.4 43.5 20.8 23.2 34.7 39.1 26.9 41.2 52.3 77.4 18.7 12.1 36.5 34.2 60.9 24.3 19.0 36.5 45.4 6.6 40.8 30.6 40.0 33.2 25.0 36.7 39.8 39.7 28.0 26.9 50.7 MOCOS "FLJ20733, HMCS, MOS" ENSG00000075643 "Molybdenum cofactor sulfurase" Q96EN8 18 36187497-36272157 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.3;liver: 16.0" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 18.8;Hepatocytes: 39.4;Proximal enterocytes: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 40.7;hTERT-HME1: 49.7;SiHa: 54.9;SK-MEL-30: 38.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039412, HPA047958" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA039412: AB_2676496, HPA047958: AB_2680225" "unprognostic (3.07e-3)" "unprognostic (1.81e-1)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-3)" "unprognostic (2.55e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.55e-4)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.91e-2)" "prognostic unfavorable (3.03e-12)" "unprognostic (8.98e-2)" "unprognostic (2.37e-1)" "unprognostic (4.09e-1)" "unprognostic (6.35e-2)" 2.0 10.3 0.3 0.9 0.3 0.3 2.5 0.5 0.5 0.9 0.5 1.6 6.1 0.8 1.9 3.8 1.7 1.4 0.3 0.4 0.4 1.2 16.0 1.6 0.2 1.2 0.3 6.4 0.8 2.3 2.0 1.0 1.3 1.3 1.6 0.7 1.8 3.3 0.6 2.0 6.4 0.6 0.2 0.3 1.6 0.9 0.6 0.1 1.2 0.4 1.2 2.7 0.7 0.3 14.3 4.8 0.2 0.1 4.3 5.5 2.9 8.2 4.6 3.9 10.0 3.1 4.4 0.1 2.5 13.4 1.0 8.6 2.9 12.9 5.4 2.4 2.3 0.2 13.5 11.8 14.6 0.1 3.8 8.7 40.7 15.2 49.7 0.5 0.6 0.1 4.9 0.1 6.2 3.6 0.0 0.1 0.8 3.4 4.1 0.0 0.1 0.0 5.5 18.5 0.1 1.2 54.9 3.3 38.8 0.9 2.5 0.2 2.7 3.0 3.7 6.7 1.4 0.1 0.1 0.1 7.8 0.1 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.5 0.4 0.4 1.2 0.3 1.3 0.2 0.6 0.3 0.9 12.8 5.0 0.3 0.9 0.6 1.4 3.7 1.8 0.3 4.5 1.9 1.0 4.3 6.4 0.0 2.1 0.5 0.2 2.2 0.0 3.1 7.2 5.9 3.4 0.8 3.0 0.0 0.9 12.4 4.3 2.4 1.5 18.8 0.0 2.0 0.4 39.4 0.6 0.0 1.1 3.1 6.1 0.6 2.6 3.2 1.8 1.0 3.6 4.7 11.9 6.6 0.0 1.0 0.3 4.6 2.3 9.1 0.9 2.3 22.4 0.2 4.5 0.5 0.0 6.5 1.2 0.1 0.3 5.1 1.3 2.3 0.5 2.7 4.5 2.2 FHOD3 "FHOS2, FLJ22297, FLJ22717, KIAA1695" ENSG00000134775 "Formin homology 2 domain containing 3" Q2V2M9 18 36297714-36780055 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 172.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.5;Cone photoreceptor cells: 87.6;Excitatory neurons: 132.2;Granulosa cells: 84.9;Inhibitory neurons: 186.5;Oligodendrocyte precursor cells: 114.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 72.3;HDLM-2: 80.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021827, HPA024696" Uncertain "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA021827: AB_1848571, HPA024696: AB_1848573" "unprognostic (8.46e-2)" "unprognostic (8.76e-2)" "unprognostic (6.34e-2)" "unprognostic (3.44e-1)" "unprognostic (8.96e-2)" "unprognostic (8.30e-2)" "unprognostic (4.11e-4)" "unprognostic (2.73e-2)" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (2.16e-3)" "unprognostic (4.55e-2)" "prognostic favorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (4.10e-2)" "unprognostic (3.00e-3)" "unprognostic (1.20e-1)" 3.4 32.1 13.2 2.4 14.3 0.1 6.1 8.7 17.7 5.6 13.9 14.5 1.6 3.0 42.2 9.4 11.2 7.2 172.8 13.8 12.3 23.2 1.4 1.5 1.3 37.9 15.1 6.9 2.1 1.0 10.5 1.3 36.8 27.9 3.4 36.1 11.3 62.8 49.5 6.5 5.5 10.1 11.5 1.3 3.2 4.1 8.5 2.4 3.6 20.5 4.0 14.6 5.2 13.5 15.5 5.4 34.3 8.2 0.2 0.0 2.6 34.1 72.3 6.7 6.5 0.0 24.5 2.8 8.9 16.3 19.2 19.5 11.4 14.8 4.0 80.1 4.0 0.0 1.0 0.1 0.4 0.0 1.1 4.5 7.1 3.6 1.5 36.6 0.2 0.0 0.0 0.2 8.0 0.0 0.1 0.2 7.5 0.0 4.9 0.0 0.0 18.9 32.5 17.0 19.0 44.6 7.4 0.1 4.6 3.0 0.2 0.1 39.6 21.3 1.6 0.9 29.5 31.8 0.0 0.0 23.8 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 14.3 8.7 17.7 13.8 12.3 37.9 15.1 36.8 11.5 8.5 13.5 0.4 0.0 0.0 104.5 0.0 3.2 0.9 8.9 14.8 6.5 2.3 11.4 38.0 0.0 2.7 12.9 87.6 0.1 0.0 0.2 3.9 1.3 1.7 10.2 1.7 0.6 0.0 0.4 132.2 0.9 11.3 7.9 1.1 0.6 0.0 84.9 0.0 0.0 0.2 0.0 186.5 0.2 6.1 0.0 0.6 0.4 0.0 0.3 10.6 11.2 0.0 7.3 0.0 114.1 3.4 3.3 0.1 0.4 0.0 0.6 0.0 7.9 15.3 33.6 0.0 11.2 6.3 2.2 2.8 1.6 0.6 0.4 0.4 29.9 0.3 0.3 TPGS2 "C18orf10, DKFZP586M1523, HsT3006" ENSG00000134779 "Tubulin polyglutamylase complex subunit 2" Q68CL5 18 36777647-36829216 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 499.2;Late spermatids: 1012.6;Spermatocytes: 318.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 266.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040596, HPA040617" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA040596: AB_10796458, HPA040617: AB_10794037" "unprognostic (6.51e-3)" "prognostic favorable (4.09e-4)" "unprognostic (5.82e-2)" "unprognostic (1.18e-1)" "unprognostic (5.05e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (1.24e-5)" "unprognostic (3.78e-2)" "unprognostic (2.36e-1)" "prognostic favorable (1.93e-5)" "unprognostic (2.50e-2)" "unprognostic (1.33e-3)" "unprognostic (7.19e-3)" "unprognostic (2.51e-2)" "prognostic favorable (7.74e-4)" "unprognostic (4.03e-2)" "unprognostic (5.28e-2)" 44.8 52.7 65.8 29.5 70.4 70.2 40.2 68.8 71.3 44.8 169.7 40.1 27.2 37.4 32.5 56.8 54.7 43.5 58.9 71.4 82.7 46.2 27.2 48.6 38.8 80.9 89.1 67.6 35.2 41.1 23.0 35.4 92.2 34.2 41.0 58.4 32.6 34.8 16.4 46.4 34.5 48.4 65.3 24.9 31.9 202.9 68.6 101.3 49.6 22.1 64.6 54.1 37.7 69.9 142.4 109.6 208.8 183.2 102.3 111.0 87.6 152.7 207.6 210.6 252.9 53.2 99.6 138.8 104.0 307.5 133.5 138.1 173.9 215.3 246.9 182.2 59.0 97.2 186.5 145.8 104.9 126.5 83.1 148.9 110.0 188.0 96.6 202.5 253.6 142.1 143.1 100.0 279.9 84.0 202.2 74.0 126.8 62.8 70.9 149.4 192.8 169.6 235.3 136.8 146.5 160.3 229.8 59.4 67.6 181.4 114.1 120.6 143.0 210.6 78.1 30.3 123.6 126.5 129.4 164.4 170.3 101.3 120.9 266.1 44.0 89.5 44.2 50.3 44.4 44.7 51.4 46.2 45.1 31.5 38.5 43.5 13.5 52.3 61.0 35.8 94.3 52.8 65.8 70.4 68.8 71.3 71.4 82.7 80.9 89.1 92.2 65.3 68.6 69.9 26.2 44.8 34.7 9.4 23.7 28.9 39.3 87.8 25.6 21.5 38.2 42.5 19.7 54.3 64.1 25.8 8.4 81.2 25.6 13.9 72.4 123.2 499.2 68.8 27.1 32.0 19.8 125.8 27.1 77.2 144.5 41.3 25.0 50.7 19.0 41.6 36.8 21.7 85.8 8.4 30.9 24.5 69.2 29.9 32.4 1012.6 36.7 27.2 32.0 13.1 58.9 35.7 43.3 11.1 23.0 92.4 23.9 49.2 29.2 18.9 34.6 47.8 77.5 22.8 32.9 21.2 39.5 318.9 131.1 48.4 39.9 31.3 27.3 76.5 43.2 43.2 KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.8;Alveolar cells type 2: 228.3;Inhibitory neurons: 113.9;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 178.0;Respiratory ciliated cells: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040946 Approved Approved "Nuclear speckles,Vesicles,Lipid droplets" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Vesicles, Lipid droplets" "HPA040946: AB_10794998" "unprognostic (3.66e-2)" "unprognostic (5.37e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (3.18e-3)" "unprognostic (4.85e-2)" "unprognostic (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (3.36e-2)" "unprognostic (2.64e-3)" 6.9 7.1 24.6 7.7 33.8 22.0 5.7 54.3 62.5 5.0 10.1 6.2 9.0 9.5 9.0 6.6 6.1 7.2 6.6 27.2 13.9 7.2 7.0 7.3 7.5 5.5 1.5 13.7 5.3 5.1 2.8 8.3 12.5 7.6 5.5 37.9 9.4 3.9 11.0 13.6 9.4 5.5 0.6 8.3 9.0 16.8 12.6 4.0 7.0 4.1 4.6 4.6 3.6 75.8 26.2 7.4 11.2 13.5 3.8 5.8 10.5 10.7 4.0 5.1 3.4 12.9 16.4 18.1 32.8 4.1 8.6 11.7 4.2 4.7 6.4 15.3 5.0 22.9 24.6 9.3 3.6 16.0 11.9 5.4 5.8 5.6 5.0 5.5 4.4 10.9 18.1 40.7 5.0 23.0 10.6 10.6 25.0 9.6 11.4 14.0 11.9 12.8 4.2 22.2 11.7 13.5 12.8 15.9 6.7 20.4 23.3 8.3 13.8 22.4 29.5 13.3 11.2 32.2 43.8 14.4 11.0 11.3 15.4 23.8 6.7 9.9 8.2 5.0 9.8 7.4 7.2 7.0 3.2 11.4 9.3 7.5 13.2 7.4 8.0 5.5 9.4 4.0 24.6 33.8 54.3 62.5 27.2 13.9 5.5 1.5 12.5 0.6 12.6 75.8 10.9 230.8 228.3 85.5 13.3 5.7 7.9 7.0 6.8 36.1 6.5 7.1 6.0 7.2 106.8 5.5 20.9 8.8 6.5 1.7 5.9 7.6 51.9 6.8 10.5 18.2 3.0 5.5 83.8 5.8 7.8 23.9 5.1 6.9 107.9 13.5 9.7 3.0 6.6 16.8 113.9 3.2 2.0 4.4 4.6 13.0 9.3 18.3 7.2 94.6 5.0 10.1 19.6 117.6 178.0 6.3 3.7 7.9 8.0 3.6 4.4 4.4 122.7 30.9 0.0 14.3 11.0 45.3 19.6 6.6 7.0 3.8 20.6 11.5 4.5 5.0 CELF4 BRUNOL4 ENSG00000101489 "CUGBP Elav-like family member 4" Q9BZC1 18 37243040-37565827 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 122.2" "Group enriched" "Detected in many" 4 "Bipolar cells: 126.4;Excitatory neurons: 197.7;Horizontal cells: 294.4;Inhibitory neurons: 197.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "SCLC-21H: 46.7;SH-SY5Y: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013322, HPA037986" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA013322: , HPA037986: AB_10673035" "unprognostic (7.87e-3)" "unprognostic (2.31e-2)" "unprognostic (4.31e-3)" "unprognostic (3.42e-7)" "unprognostic (2.95e-2)" "unprognostic (2.95e-2)" "unprognostic (3.72e-3)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.92e-2)" "unprognostic (1.00e-2)" "unprognostic (3.49e-1)" "unprognostic (1.69e-2)" "unprognostic (2.48e-1)" "unprognostic (8.32e-3)" "unprognostic (6.13e-2)" 0.6 11.5 102.9 1.1 104.8 0.3 0.4 59.5 122.2 0.3 11.1 1.9 0.8 0.4 0.6 0.5 0.4 1.2 1.0 96.4 81.2 1.5 0.3 0.6 0.8 58.3 69.7 1.3 3.9 0.3 28.4 0.8 71.4 0.8 0.4 21.4 1.7 0.2 11.0 1.3 1.2 0.5 34.6 1.1 1.7 3.6 57.4 0.0 1.5 0.2 0.1 0.2 0.5 94.4 0.1 0.1 0.7 0.6 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.5 0.3 1.0 0.0 0.2 0.6 0.1 0.0 0.0 0.8 0.4 0.0 1.8 0.4 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.8 0.0 0.3 0.1 0.5 1.7 0.0 0.3 0.1 0.0 2.1 0.0 0.1 46.7 11.7 1.1 0.3 0.1 0.3 0.2 0.1 0.0 1.4 0.7 0.3 0.2 2.9 0.5 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.9 104.8 59.5 122.2 96.4 81.2 58.3 69.7 71.4 34.6 57.4 94.4 0.2 0.0 0.0 22.5 0.8 0.4 1.4 0.9 0.0 126.4 0.4 0.5 1.9 0.0 0.3 0.0 41.7 0.3 0.1 0.2 0.0 0.4 46.9 0.7 0.9 4.1 12.7 0.0 197.7 1.1 0.3 1.2 2.0 1.2 0.0 1.8 0.7 0.0 8.6 294.4 197.5 2.5 6.1 0.0 0.0 22.6 0.6 0.3 0.0 14.0 0.0 7.3 0.0 19.1 12.3 2.6 0.2 5.3 0.0 2.7 4.4 6.7 0.3 22.0 0.0 4.3 8.2 12.6 7.6 0.0 0.6 0.3 0.3 1.5 3.5 1.2 PIK3C3 Vps34 ENSG00000078142 "Phosphatidylinositol 3-kinase catalytic subunit type 3" Q8NEB9 18 41955234-42087830 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 114.9;Inhibitory neurons: 104.1;Oligodendrocytes: 115.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040718 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA040718: AB_10793862" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (1.40e-2)" "unprognostic (3.55e-3)" "unprognostic (6.15e-2)" "unprognostic (3.61e-2)" "unprognostic (6.00e-3)" "unprognostic (1.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.86e-2)" "unprognostic (6.41e-2)" "prognostic favorable (4.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.76e-1)" "unprognostic (6.85e-3)" 10.9 16.1 6.8 12.0 10.0 15.9 16.4 18.2 11.5 13.2 12.7 11.7 8.9 15.0 16.6 11.8 12.2 12.1 11.5 7.3 7.8 16.2 14.3 11.7 14.1 8.3 7.0 17.0 9.0 18.6 8.0 17.2 9.9 12.8 13.7 16.7 10.9 12.5 12.2 11.4 10.6 13.9 8.7 13.3 11.5 18.0 7.6 18.5 15.3 16.2 15.8 15.1 9.9 12.9 16.2 11.3 27.8 21.3 31.6 33.8 17.1 31.4 39.8 24.7 33.2 5.4 8.0 10.0 17.6 31.8 19.4 26.0 22.1 17.5 34.2 16.3 15.5 20.8 15.4 21.7 26.3 30.9 22.1 37.3 25.8 23.2 29.9 37.9 25.6 19.9 20.9 12.2 34.3 5.3 13.6 19.8 20.4 6.0 8.1 81.9 21.0 26.1 28.3 17.1 24.2 28.1 10.2 7.3 22.2 30.8 10.8 24.8 33.7 33.3 9.7 7.4 14.6 33.3 42.2 11.3 27.5 41.4 18.0 20.5 9.9 21.2 9.2 11.0 10.3 11.4 9.3 11.5 10.2 10.1 11.8 8.9 19.2 12.1 12.5 5.8 17.0 8.2 6.8 10.0 18.2 11.5 7.3 7.8 8.3 7.0 9.9 8.7 7.6 12.9 22.4 22.4 36.9 70.2 21.1 11.5 10.8 15.3 15.4 28.2 11.5 11.0 23.5 4.3 27.3 14.7 20.9 20.6 26.8 13.8 7.9 14.4 28.6 16.9 22.4 19.9 4.9 19.1 114.9 10.3 13.3 22.4 13.7 18.3 17.1 25.4 17.2 13.4 15.6 55.5 104.1 11.5 16.2 17.9 10.1 13.2 14.6 20.9 7.2 58.1 21.5 26.2 13.4 83.4 115.6 14.3 10.0 24.0 18.2 14.5 12.9 12.3 22.4 22.5 19.7 25.4 18.9 20.0 18.6 14.3 11.4 27.4 23.8 24.7 10.6 15.9 RIT2 "RIBA, RIN" ENSG00000152214 "Ras like without CAAX 2" Q99578 18 42743227-43115691 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 25.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 225.8;Oligodendrocyte precursor cells: 202.5" "Cancer enriched" "Detected in single" 49 "glioma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA072174, HPA072526" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Golgi apparatus, Cytosol" "HPA072174: AB_2732195, HPA072526: " "unprognostic (1.37e-2)" "unprognostic (4.15e-1)" "unprognostic (2.14e-1)" 0.0 1.9 9.3 0.1 10.6 0.0 0.0 25.9 16.8 0.1 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 13.3 0.0 0.0 0.0 0.0 12.8 9.2 0.0 0.0 0.0 0.5 0.0 17.4 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 8.9 0.0 0.0 0.2 11.6 0.0 0.0 0.0 0.0 0.0 0.2 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 10.6 25.9 16.8 8.8 13.3 12.8 9.2 17.4 8.9 11.6 8.8 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 225.8 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 42.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 3.7 0.0 1.0 0.0 202.5 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.1 1.4 0.2 0.0 0.0 2.1 0.0 0.5 0.0 0.0 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 SETBP1 "KIAA0437, SEB" ENSG00000152217 "SET binding protein 1" Q9Y6X0 18 44680173-45068510 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" DNA-binding "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 349.0;Inhibitory neurons: 548.3;Oligodendrocyte precursor cells: 170.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 11.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.0;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 5 "B-cells: 3.0;dendritic cells: 2.8;monocytes: 1.0" "Cell line enhanced" "Detected in many" "AF22: 16.1;Karpas-707: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049022, HPA057259" Uncertain Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 66000 "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA049022: AB_2680602, HPA057259: AB_2683384" "unprognostic (1.25e-1)" "unprognostic (1.57e-1)" "unprognostic (1.11e-1)" "unprognostic (1.97e-2)" "unprognostic (4.63e-2)" "unprognostic (1.80e-1)" "unprognostic (1.91e-1)" "unprognostic (3.57e-2)" "unprognostic (3.49e-1)" "unprognostic (2.01e-2)" "unprognostic (2.71e-3)" "unprognostic (6.52e-2)" "prognostic favorable (6.34e-8)" "unprognostic (2.18e-2)" "unprognostic (2.29e-1)" "unprognostic (6.06e-2)" "unprognostic (7.81e-5)" 7.3 1.9 2.0 3.7 3.7 1.8 6.3 11.6 5.7 11.6 0.0 10.9 1.7 8.3 7.2 4.5 7.2 5.0 4.3 2.6 0.2 7.4 4.7 6.6 5.3 0.0 0.1 7.7 5.8 3.7 2.7 7.2 0.1 7.8 3.5 3.0 4.3 9.2 10.7 4.4 4.6 7.4 0.0 3.7 5.6 1.8 0.0 4.4 5.1 9.7 4.7 8.1 8.5 3.8 0.0 2.4 16.1 0.0 4.1 1.2 1.0 1.3 3.0 1.5 1.3 0.2 0.0 1.0 0.5 1.8 1.0 4.8 1.8 4.9 1.0 1.4 0.8 0.0 1.8 1.2 0.0 0.0 0.0 3.8 2.0 0.0 3.0 2.7 0.5 0.0 0.1 44.7 0.4 0.8 0.0 0.1 2.0 0.0 1.1 5.6 0.0 5.5 4.9 3.9 8.2 4.2 0.0 0.0 0.9 7.1 2.2 0.0 0.0 9.5 3.3 0.0 7.7 8.6 0.5 0.0 5.8 0.2 5.5 0.1 0.0 0.0 0.4 0.6 0.0 2.0 0.0 0.2 0.0 3.0 0.0 0.1 0.0 0.0 1.0 2.8 0.0 0.1 2.0 3.7 11.6 5.7 2.6 0.2 0.0 0.1 0.1 0.0 0.0 3.8 7.6 0.0 1.8 85.5 42.4 15.4 8.6 8.3 7.4 12.5 11.0 12.6 3.9 14.3 4.2 16.5 18.8 1.5 25.5 1.6 3.9 4.5 1.3 12.9 15.6 8.3 12.0 0.8 349.0 3.5 1.4 29.3 4.1 14.8 0.0 0.7 17.9 16.5 2.0 3.3 548.3 4.4 10.2 2.4 8.7 3.7 62.7 4.6 3.6 88.1 1.5 10.7 6.2 170.4 62.9 3.7 9.1 39.9 29.6 8.1 0.4 10.5 5.8 18.2 6.6 18.4 28.6 0.3 0.8 4.0 15.2 0.8 5.9 0.1 4.7 1.5 SLC14A2 "HUT2, UT2" ENSG00000132874 "Solute carrier family 14 member 2" Q15849 18 45212995-45683688 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.5;kidney: 3.2" "Cell type enriched" "Detected in many" 7 "Collecting duct cells: 77.3" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.5" "Cell line enriched" "Detected in single" 7 "U-266/70: 4.9" "Region enhanced" "Detected in many" "basal ganglia: 16.9" "Not detected" "Not detected" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.33e-1)" "unprognostic (1.42e-1)" "unprognostic (1.85e-2)" "unprognostic (2.54e-2)" "unprognostic (7.80e-2)" "unprognostic (1.11e-2)" "unprognostic (7.89e-3)" "unprognostic (3.76e-3)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.27e-3)" "unprognostic (8.96e-2)" "unprognostic (3.50e-3)" "unprognostic (1.20e-1)" "unprognostic (7.64e-2)" "unprognostic (7.52e-2)" "unprognostic (6.62e-2)" 1.5 1.1 0.2 0.2 0.2 0.3 0.1 0.3 0.6 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 3.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.2 1.1 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.7 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.7 0.2 4.9 0.2 0.1 0.2 0.7 0.1 0.5 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.2 0.2 0.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 6.4 9.6 5.2 0.7 0.6 0.9 0.3 0.0 1.1 0.4 0.3 0.9 0.0 1.9 77.3 2.1 0.3 0.6 0.3 0.0 0.0 1.3 0.2 0.3 0.9 0.0 0.0 8.8 0.0 0.5 2.4 0.0 0.3 3.8 0.1 1.1 0.0 0.4 1.7 10.6 0.5 0.0 0.3 2.0 1.4 0.6 0.8 1.8 2.8 0.2 0.9 1.0 6.6 1.0 0.1 1.2 0.7 0.1 0.5 4.9 0.2 1.5 2.0 0.0 0.4 0.2 0.3 0.4 0.0 0.1 0.8 1.0 0.2 0.2 0.5 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SIGLEC15 "CD33L3, HsT1361" ENSG00000197046 "Sialic acid binding Ig like lectin 15" Q6ZMC9 18 45825675-45844094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 1.7;intestine: 3.0;urinary bladder: 1.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.6;Hofbauer cells: 10.1;Macrophages: 3.7;Pancreatic endocrine cells: 3.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "classical monocyte: 3.0;myeloid DC: 1.0" "Group enriched" "Detected in many" 21 "dendritic cells: 1.0;monocytes: 3.0" "Cell line enriched" "Detected in some" 5 "U-87 MG: 124.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA053509 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus" "HPA053509: " "unprognostic (3.89e-3)" "unprognostic (1.87e-2)" "unprognostic (1.77e-1)" "unprognostic (7.18e-3)" "unprognostic (2.27e-1)" "unprognostic (8.07e-2)" "unprognostic (5.91e-2)" "unprognostic (2.71e-1)" "unprognostic (9.63e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-2)" "unprognostic (7.65e-2)" "unprognostic (6.55e-2)" "unprognostic (1.42e-1)" "unprognostic (6.06e-2)" "unprognostic (4.40e-2)" "prognostic favorable (9.14e-5)" 0.0 0.4 0.1 0.3 0.4 0.0 1.7 0.6 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 1.0 1.3 0.0 0.0 0.2 0.0 0.0 0.6 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.4 10.9 2.1 0.3 0.0 22.7 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 5.5 0.0 0.1 1.3 0.0 0.0 0.0 124.2 2.9 0.2 0.0 3.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 0.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.9 1.3 0.0 0.0 1.0 3.6 0.9 0.8 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.5 0.4 0.2 1.0 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.7 0.0 0.0 2.2 0.4 10.1 1.7 0.1 0.2 0.0 1.6 2.5 0.0 0.0 3.7 0.0 0.0 1.6 0.0 1.0 0.0 0.0 3.5 0.1 0.0 0.0 1.1 1.2 0.1 0.0 1.0 0.0 1.5 0.4 1.2 0.1 0.0 0.3 0.0 0.3 0.0 0.1 2.8 EPG5 "hEPG5, KIAA1632" ENSG00000152223 "Ectopic P-granules autophagy protein 5 homolog" Q9HCE0 18 45847609-45967329 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 53.1;Oligodendrocytes: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "LHCN-M2: 55.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031689 Uncertain Approved "Nuclear speckles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "HPA031689: AB_10609997" "unprognostic (3.43e-1)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (6.84e-2)" "unprognostic (2.20e-2)" "unprognostic (4.59e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-1)" "unprognostic (4.66e-1)" "unprognostic (4.87e-1)" "unprognostic (1.15e-2)" "unprognostic (7.50e-2)" "prognostic favorable (4.04e-5)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (4.05e-1)" "unprognostic (1.18e-1)" 6.6 6.8 5.8 4.4 6.0 13.8 6.8 6.3 6.2 7.1 5.1 5.8 3.2 6.1 5.8 7.1 6.0 3.2 8.4 6.2 5.3 6.6 6.0 8.8 5.7 5.1 8.1 8.9 6.3 6.9 7.6 4.5 5.3 5.9 4.0 8.6 6.0 3.7 8.6 10.1 6.0 4.1 4.5 9.5 5.6 4.8 5.8 8.4 9.3 6.7 5.9 5.4 6.6 6.3 5.3 4.1 4.1 3.0 13.8 16.6 4.1 33.2 13.7 18.7 19.4 1.2 3.9 5.4 2.0 25.0 22.5 4.9 5.5 6.6 23.7 4.5 2.3 4.2 4.7 4.2 13.1 7.2 10.4 11.2 6.0 20.6 14.0 16.5 9.4 4.7 3.7 2.8 55.8 3.7 3.2 6.9 2.0 1.9 2.5 3.0 5.1 3.8 8.8 7.3 4.4 3.4 5.9 2.4 7.0 5.8 3.4 5.1 23.0 23.2 4.9 3.4 9.2 5.7 4.3 3.0 9.9 6.2 7.7 0.4 0.7 0.7 1.5 0.7 1.4 0.4 0.9 0.8 0.5 0.6 0.7 0.9 0.8 0.4 0.6 0.6 0.5 0.3 5.8 6.0 6.3 6.2 6.2 5.3 5.1 8.1 5.3 4.5 5.8 6.3 8.8 19.2 10.5 24.5 9.0 10.3 4.6 6.8 8.0 16.7 11.9 8.3 17.1 10.0 7.4 11.0 25.0 7.6 15.7 5.8 1.9 6.5 4.6 9.0 9.8 9.3 8.3 11.4 53.1 3.6 4.4 7.8 6.1 16.9 7.0 14.4 13.6 10.3 12.2 13.5 46.5 6.9 6.1 16.0 6.2 3.0 12.5 11.5 14.2 40.3 16.6 6.5 27.8 40.2 51.4 7.8 6.5 11.7 10.0 9.1 6.2 8.3 10.5 17.4 13.1 9.8 6.7 8.4 7.1 5.9 13.2 9.0 15.4 9.8 6.5 9.4 PSTPIP2 ENSG00000152229 "Proline-serine-threonine phosphatase interacting protein 2" Q9H939 18 45983536-46072272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 72.4;lymphoid tissue: 63.4;skeletal muscle: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 44.6;Erythroid cells: 46.7;Macrophages: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 112.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 102.0;HMC-1: 108.3" "Low region specificity" "Detected in all" "HPA040923, HPA040944" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" No No 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Mitochondria" Nucleoplasm "HPA040923: AB_10794429, HPA040944: AB_10795485" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-2)" "unprognostic (4.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (5.21e-2)" "unprognostic (3.55e-1)" "unprognostic (1.61e-1)" "unprognostic (1.93e-1)" 4.4 4.6 0.9 11.1 0.9 72.4 8.5 0.8 1.5 4.2 1.8 4.4 3.6 2.9 1.4 5.1 4.0 5.3 2.1 0.8 1.1 3.7 10.0 11.4 6.3 1.8 1.2 3.6 3.5 3.8 2.9 12.1 1.5 8.0 5.1 2.8 5.9 2.7 33.0 8.8 4.5 4.6 1.1 63.4 6.4 1.3 1.2 3.9 2.1 5.8 4.9 9.6 4.3 1.4 2.9 0.0 3.8 0.1 0.9 6.7 20.6 15.0 7.4 5.3 4.5 11.6 4.0 0.1 0.9 5.0 0.0 36.2 20.3 28.1 6.6 0.0 3.2 102.0 4.6 0.2 5.9 6.0 108.3 5.0 34.4 5.0 16.3 4.8 10.6 0.2 24.8 0.1 23.1 3.6 0.9 0.1 2.3 0.0 0.1 0.1 7.5 4.9 11.2 37.0 0.3 2.1 2.4 10.3 0.5 28.2 32.6 12.0 7.6 0.6 8.2 0.8 0.2 0.1 0.3 0.1 1.3 0.2 0.4 77.3 25.3 112.8 10.4 35.0 3.6 0.1 6.2 7.7 25.3 0.1 7.2 8.8 13.5 2.9 36.4 0.9 4.1 20.0 0.9 0.9 0.8 1.5 0.8 1.1 1.8 1.2 1.5 1.1 1.2 1.4 1.7 12.8 11.6 0.7 2.4 13.8 19.4 44.6 15.4 0.7 11.1 17.1 3.5 2.8 24.9 0.0 0.0 26.6 21.8 0.6 3.9 9.6 2.0 4.1 2.6 3.1 1.2 46.7 1.6 3.9 3.3 4.2 11.2 11.2 43.6 20.6 7.1 17.3 14.6 0.0 1.4 4.2 6.1 42.5 5.5 7.3 2.8 58.7 7.2 2.8 37.4 10.9 25.7 2.0 0.9 17.7 0.3 2.2 3.6 39.7 0.5 4.1 13.0 0.4 6.6 3.1 7.7 1.1 1.6 7.3 10.2 8.8 17.8 7.1 2.4 21.8 ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1760.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 784.3;Distal tubular cells: 1173.9;Extravillous trophoblasts: 463.0;Proximal tubular cells: 939.6;Syncytiotrophoblasts: 578.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013067, HPA040622, HPA044202" Enhanced Supported Mitochondria NA NA 8800000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "CAB013067: AB_221511, HPA040622: AB_2677048, HPA044202: AB_2678855" "unprognostic (3.08e-2)" "unprognostic (9.13e-2)" "unprognostic (1.84e-2)" "unprognostic (3.54e-1)" "unprognostic (6.36e-2)" "unprognostic (2.61e-1)" "unprognostic (1.89e-2)" "unprognostic (6.79e-2)" "unprognostic (8.31e-2)" "unprognostic (4.79e-2)" "unprognostic (7.30e-3)" "unprognostic (1.50e-2)" "prognostic favorable (1.22e-15)" "unprognostic (4.60e-3)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (4.87e-3)" 251.3 453.6 198.6 177.7 209.2 210.5 260.4 233.0 251.4 195.5 401.9 414.0 438.9 192.6 225.6 362.6 227.2 146.3 1498.3 207.7 246.0 730.4 441.6 175.1 223.7 234.6 237.8 211.1 299.9 868.5 277.4 201.7 226.0 211.4 419.8 465.4 307.4 265.9 1602.0 290.3 335.0 233.0 205.4 226.8 419.1 167.6 226.7 277.3 261.4 1760.3 337.6 244.9 224.7 209.6 355.2 353.0 459.6 434.3 546.0 601.8 508.6 399.5 562.4 601.0 522.8 532.7 271.9 833.2 238.9 487.4 322.3 641.7 801.1 614.1 556.4 373.0 450.3 551.7 413.3 667.2 357.1 1182.7 501.6 559.2 422.3 434.6 448.2 481.3 630.4 442.5 454.0 477.2 521.8 367.6 612.8 579.7 432.3 344.5 367.6 596.5 533.8 1131.4 816.2 849.7 465.7 434.7 293.3 361.5 506.9 428.6 466.3 679.3 370.4 328.7 282.7 174.9 354.9 542.5 501.5 533.0 328.1 698.0 358.7 119.1 573.9 162.7 353.6 511.8 455.9 492.3 422.7 388.4 959.5 392.9 503.3 421.7 55.9 414.5 485.1 468.3 527.4 1339.1 198.6 209.2 233.0 251.4 207.7 246.0 234.6 237.8 226.0 205.4 226.7 209.6 79.2 169.9 167.8 0.0 49.9 0.0 0.0 0.0 0.0 0.0 205.7 169.8 0.0 0.0 100.3 171.0 0.0 784.3 86.3 0.0 1173.9 358.3 0.0 125.3 163.3 73.0 0.0 0.0 0.0 269.7 463.0 97.8 0.0 119.3 89.6 198.7 0.0 0.0 409.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 179.9 0.0 0.0 0.0 0.0 199.1 0.0 0.0 24.0 0.0 0.0 939.6 95.5 0.0 0.0 0.0 87.1 0.0 0.0 0.0 0.0 578.2 54.6 319.2 0.0 0.0 HAUS1 "CCDC5, FLJ40084, HEI-C, HsT1461" ENSG00000152240 "HAUS augmin like complex subunit 1" Q96CS2 18 46104378-46128333 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040601, HPA040652" Supported Supported Centrosome,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Centrosome "HPA040601: AB_10794743, HPA040652: AB_10793966" "unprognostic (1.74e-2)" "unprognostic (1.89e-2)" "unprognostic (8.13e-3)" "unprognostic (1.92e-1)" "unprognostic (2.29e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.45e-4)" "unprognostic (1.39e-1)" "unprognostic (4.76e-3)" "prognostic favorable (1.55e-4)" "unprognostic (3.75e-1)" "prognostic unfavorable (6.76e-4)" "unprognostic (5.97e-3)" "unprognostic (5.40e-2)" "unprognostic (9.79e-3)" "unprognostic (3.66e-2)" "unprognostic (7.96e-2)" 14.3 11.0 7.2 18.4 7.2 37.8 18.9 7.3 10.2 13.7 9.0 18.5 14.3 17.0 38.7 14.5 13.4 16.9 11.8 7.0 7.8 13.0 13.7 12.2 35.6 7.5 7.6 26.4 11.4 14.3 10.7 17.8 7.8 10.4 22.1 9.5 10.5 12.9 7.2 10.1 14.3 16.8 8.0 14.6 13.0 16.2 7.3 41.4 13.3 13.2 39.5 16.2 11.9 8.1 72.8 43.6 157.3 86.9 38.8 59.4 42.5 68.4 65.7 105.5 104.4 43.2 39.5 136.4 40.5 48.3 49.8 74.6 94.0 56.4 115.1 77.7 64.2 99.2 40.7 82.0 32.5 184.2 59.7 28.6 21.6 64.6 33.3 45.6 115.1 91.5 72.4 39.8 94.2 41.9 150.0 87.7 101.1 33.0 24.9 144.6 112.4 98.4 85.4 49.9 74.3 77.2 64.3 22.3 52.9 60.7 33.3 89.0 67.9 62.8 42.1 27.9 73.4 43.5 73.2 130.6 39.9 157.0 74.0 11.1 46.5 36.7 40.3 45.4 45.0 79.4 53.0 48.9 58.3 64.8 38.1 45.0 4.9 55.9 35.8 62.5 99.9 55.4 7.2 7.2 7.3 10.2 7.0 7.8 7.5 7.6 7.8 8.0 7.3 8.1 20.6 12.8 12.2 3.3 26.5 17.5 15.8 47.8 16.5 6.1 16.4 18.7 10.1 15.7 33.0 14.7 4.2 58.7 22.0 11.1 17.6 38.2 7.5 15.9 18.3 29.4 12.1 53.9 4.2 42.3 111.7 25.1 7.1 14.5 29.8 31.3 23.2 6.9 50.9 11.8 4.8 24.1 28.5 33.6 24.7 12.4 22.7 25.8 21.4 4.7 45.8 21.5 37.0 8.0 5.2 31.8 12.4 25.9 21.9 8.1 14.3 24.7 29.3 8.7 19.7 15.9 20.2 50.8 55.8 15.3 15.5 23.7 23.9 20.7 26.8 12.9 C18orf25 "Ark2N, ARKL1, MGC12909, RNF111L1" ENSG00000152242 "Chromosome 18 open reading frame 25" Q96B23 18 46173553-46266992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051314, HPA051899" Approved Approved Nucleoplasm,Cytosol No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA051314: AB_2681438, HPA051899: AB_2681657" "unprognostic (1.44e-2)" "unprognostic (2.32e-1)" "unprognostic (2.08e-2)" "unprognostic (5.77e-3)" "unprognostic (4.46e-1)" "unprognostic (7.78e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.97e-1)" "unprognostic (7.46e-2)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" "unprognostic (5.80e-2)" "unprognostic (3.27e-2)" "unprognostic (1.24e-1)" "unprognostic (2.96e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" 8.5 6.9 9.0 8.9 8.9 34.1 10.4 12.3 10.3 11.9 18.1 8.1 7.7 9.2 7.9 37.5 9.6 6.5 15.8 8.0 8.2 8.8 8.1 9.6 12.1 10.2 12.9 9.2 6.0 18.8 6.2 8.2 11.2 8.3 9.2 27.6 13.3 7.5 23.3 13.2 8.9 9.4 7.4 11.1 8.7 12.0 10.2 15.0 11.9 16.0 15.4 9.8 16.4 9.1 18.4 17.9 14.8 16.9 10.4 9.3 19.0 26.0 13.8 27.3 23.1 13.9 20.5 14.0 24.1 17.7 9.8 40.9 27.7 17.7 29.5 23.5 8.9 12.4 16.0 10.6 17.9 23.5 16.0 8.7 20.2 31.9 26.3 15.9 11.0 12.9 14.1 16.3 15.3 13.7 17.9 11.9 13.2 6.3 7.0 16.0 17.6 20.7 26.1 32.5 20.7 10.8 19.1 13.4 13.7 17.9 8.8 14.3 16.0 24.7 17.6 6.0 24.3 21.3 19.7 22.3 12.8 24.4 27.0 4.9 8.9 18.6 6.3 9.9 11.2 6.9 12.3 9.6 8.8 9.0 8.6 6.8 22.7 3.5 14.3 12.6 8.7 6.9 9.0 8.9 12.3 10.3 8.0 8.2 10.2 12.9 11.2 7.4 10.2 9.1 18.4 12.8 9.1 16.0 19.2 25.2 10.4 11.5 11.4 14.5 13.4 9.9 30.4 5.7 9.5 14.7 20.9 8.1 26.1 15.1 1.9 9.1 2.4 42.1 14.4 16.2 12.0 16.8 62.5 6.5 10.5 12.1 13.7 39.2 15.2 9.9 11.7 13.0 9.1 13.5 45.2 10.0 6.1 13.1 18.0 3.5 8.1 12.9 7.2 22.5 11.1 12.4 9.2 25.6 25.9 20.4 10.1 10.5 16.5 13.0 9.2 7.6 16.9 30.6 19.7 14.8 11.8 20.6 14.9 14.2 31.8 24.4 18.6 6.6 10.1 23.3 RNF165 "Ark2C, ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;retina: 18.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.0;Cone photoreceptor cells: 100.1;Excitatory neurons: 47.4;Horizontal cells: 80.8;Inhibitory neurons: 34.4;NK-cells: 41.2;Oligodendrocyte precursor cells: 35.7;Rod photoreceptor cells: 49.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 10.1;HaCaT: 7.3;HeLa: 7.5;RPMI-8226: 6.4;SCLC-21H: 13.9;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA041615: AB_2677582, HPA047798: AB_2680158" "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 0.6 0.5 3.1 0.3 3.7 0.3 0.7 7.6 6.4 0.6 0.0 0.4 0.0 0.2 1.9 1.2 1.2 0.3 1.0 4.7 0.2 1.6 5.2 0.3 0.2 0.0 0.3 0.0 0.3 2.4 4.1 0.2 0.0 2.2 0.1 18.2 0.8 1.3 1.5 1.2 0.3 0.1 0.1 2.0 0.2 0.5 1.3 0.9 4.0 0.8 0.4 0.3 0.5 1.9 1.6 0.1 10.1 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 7.3 0.5 1.0 0.0 0.0 1.1 0.1 7.5 0.0 0.0 3.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 2.3 0.0 0.2 0.0 0.0 2.6 0.9 1.7 0.4 1.3 2.7 0.6 6.4 0.7 2.2 13.9 13.2 2.0 0.0 0.0 0.9 0.3 0.5 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 3.1 3.7 7.6 6.4 4.7 0.2 0.0 0.3 0.0 0.1 1.3 1.9 9.1 3.2 1.7 1.6 0.3 2.7 9.5 12.9 28.5 44.0 2.9 7.2 8.4 1.5 2.8 0.0 100.1 0.2 10.0 0.2 3.9 0.0 3.8 1.5 9.3 5.0 0.0 0.0 47.4 0.0 0.3 2.4 0.0 0.6 0.0 0.0 1.8 8.9 0.1 80.8 34.4 0.0 2.0 1.9 1.3 5.1 2.5 0.4 1.8 1.9 0.3 5.0 41.2 35.7 1.8 0.1 0.0 4.1 0.4 5.0 0.1 0.1 0.6 49.1 0.0 4.5 0.7 0.4 0.9 3.7 2.0 0.3 3.2 3.2 0.0 2.4 LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.2;kidney: 6.9;testis: 23.0" "Group enriched" "Detected in some" 70 "Early spermatids: 199.3;Late spermatids: 439.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in some" "basal ganglia: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077128 Approved "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA077128: " "unprognostic (6.95e-2)" "unprognostic (1.88e-2)" "unprognostic (4.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (7.75e-4)" "unprognostic (9.53e-2)" "unprognostic (7.91e-2)" "unprognostic (7.61e-2)" "unprognostic (9.44e-2)" "unprognostic (1.26e-2)" "unprognostic (1.93e-2)" "unprognostic (7.43e-3)" "unprognostic (6.48e-5)" "unprognostic (2.30e-1)" "unprognostic (8.10e-3)" "unprognostic (1.66e-3)" 2.3 0.0 0.5 0.0 3.4 2.8 0.6 0.0 2.1 0.0 0.1 0.1 0.0 0.1 7.2 0.0 1.7 0.2 0.9 0.3 0.0 6.9 0.0 1.0 0.0 0.0 0.1 0.1 0.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.8 0.1 23.0 0.3 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.9 1.2 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 199.3 0.0 0.1 0.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 439.4 1.8 0.3 0.0 0.0 0.3 0.0 0.0 1.5 0.6 0.0 0.0 2.2 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 4.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.2" "Cell type enhanced" "Detected in all" "Early spermatids: 521.4;Late spermatids: 519.5;Spermatocytes: 238.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068792 Enhanced Supported Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA068792: AB_2686037" "unprognostic (9.59e-3)" "unprognostic (2.14e-1)" "unprognostic (1.63e-1)" "unprognostic (2.75e-2)" "unprognostic (1.25e-1)" "unprognostic (6.39e-2)" "unprognostic (1.05e-3)" "unprognostic (3.67e-2)" "unprognostic (1.05e-1)" "unprognostic (3.71e-3)" "unprognostic (1.77e-3)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.58e-1)" "unprognostic (6.92e-2)" "prognostic unfavorable (1.27e-4)" "unprognostic (1.71e-1)" 4.8 5.4 7.3 4.1 8.1 7.4 5.1 16.9 9.8 4.9 6.4 4.9 2.8 5.0 7.5 3.7 4.5 4.6 6.8 8.7 6.2 6.4 5.9 4.3 6.2 4.7 6.9 5.0 4.2 11.8 5.6 3.9 5.4 6.5 7.0 10.9 5.5 4.4 16.1 7.7 4.2 4.7 3.7 6.0 4.5 67.2 7.9 4.6 8.2 10.2 5.2 4.1 4.4 8.0 13.7 5.5 6.1 8.7 6.0 7.5 2.9 7.0 5.6 6.0 5.5 6.5 5.1 13.7 3.7 5.3 6.1 4.5 12.3 7.5 8.5 6.6 4.6 8.5 5.4 7.7 5.9 14.3 5.8 7.7 4.5 5.3 5.6 9.7 5.5 11.9 6.4 3.5 12.0 7.4 8.2 8.3 6.7 2.5 3.5 15.0 13.1 0.1 5.5 10.4 11.7 9.0 6.4 4.1 4.7 6.8 6.1 6.3 6.9 12.8 5.5 4.5 5.3 10.1 5.4 17.7 9.5 15.1 12.8 0.7 1.7 1.2 2.0 1.3 1.3 1.6 1.8 2.4 2.0 3.0 2.5 2.1 1.0 1.9 1.3 2.1 1.9 0.8 7.3 8.1 16.9 9.8 8.7 6.2 4.7 6.9 5.4 3.7 7.9 8.0 26.3 19.2 21.9 60.4 25.0 20.6 19.9 15.2 23.9 57.7 21.8 13.2 30.7 12.8 12.6 25.8 89.6 2.6 32.8 18.1 19.6 13.5 521.4 16.6 25.4 26.0 28.5 16.6 137.9 8.9 2.3 20.6 19.4 15.9 14.5 48.4 34.2 22.3 28.1 32.0 134.9 18.0 16.2 50.3 15.7 519.5 33.5 24.2 12.4 73.1 34.7 21.9 40.2 133.7 94.0 7.9 17.1 35.0 30.3 28.4 11.8 23.1 13.9 36.0 6.6 42.5 18.2 238.7 72.4 24.7 15.3 1.4 19.2 35.6 25.5 18.0 KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47102243 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.2;Early spermatids: 91.8;Inhibitory neurons: 41.8;Late spermatids: 71.4;Oligodendrocytes: 38.7;Spermatocytes: 58.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 21.5;Daudi: 28.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040712, HPA042029" Approved Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Intermediate filaments" "HPA040712: AB_2677092, HPA042029: AB_2677807" "unprognostic (3.40e-1)" "unprognostic (7.75e-2)" "unprognostic (9.00e-3)" "unprognostic (9.28e-2)" "unprognostic (1.74e-2)" "unprognostic (6.55e-3)" "unprognostic (6.97e-2)" "unprognostic (1.28e-2)" "unprognostic (3.90e-2)" "unprognostic (5.36e-2)" "unprognostic (9.52e-6)" "unprognostic (1.28e-1)" "prognostic favorable (1.24e-7)" "unprognostic (1.64e-1)" "unprognostic (7.14e-4)" "unprognostic (1.06e-3)" "unprognostic (1.61e-1)" 5.3 3.4 9.6 1.8 11.1 2.7 4.0 14.4 14.7 3.4 23.1 2.6 1.4 2.3 5.5 2.6 7.1 4.4 4.4 9.1 9.2 10.4 6.9 3.3 3.2 10.6 11.5 3.3 2.9 18.0 8.0 1.7 11.2 4.3 2.5 10.8 4.4 2.7 6.1 7.4 2.2 1.8 8.6 3.7 2.2 15.5 10.3 1.9 17.5 2.9 2.1 2.3 3.1 12.9 2.7 5.7 3.5 21.5 7.1 7.9 1.6 2.4 2.1 1.9 2.5 0.2 7.5 28.2 2.2 4.2 2.6 0.9 6.9 0.7 1.6 2.6 3.7 1.3 2.0 0.4 2.8 1.7 2.4 16.5 2.6 3.5 0.9 4.9 0.7 12.8 1.0 2.3 11.5 2.7 1.9 3.7 7.6 4.0 3.9 7.8 1.5 0.1 6.4 0.4 7.6 8.8 2.7 0.5 1.0 11.9 15.5 16.7 1.5 7.1 0.7 2.7 1.7 1.8 1.5 19.7 3.7 18.0 13.4 0.1 0.1 0.1 0.2 0.2 0.2 0.5 0.2 0.1 0.0 0.6 0.3 0.3 0.2 0.1 0.2 0.1 0.0 0.0 9.6 11.1 14.4 14.7 9.1 9.2 10.6 11.5 11.2 8.6 10.3 12.9 3.7 0.0 1.1 84.2 1.0 1.5 3.0 2.9 8.0 9.9 1.6 1.3 2.9 1.5 5.2 3.7 6.2 0.0 0.2 2.5 13.7 0.9 91.8 22.6 6.2 2.5 0.0 1.7 28.2 0.2 0.0 3.1 3.6 1.6 0.0 3.9 2.2 4.2 3.6 11.8 41.8 0.7 2.0 1.9 0.9 71.4 1.5 1.5 3.6 18.7 0.9 2.6 0.0 26.7 38.7 0.2 0.3 2.2 0.4 1.0 0.2 12.1 35.2 2.3 0.0 7.5 1.9 58.7 4.6 2.8 1.1 0.1 0.6 2.6 2.3 1.9 AC090373.2 ENSG00000288616 "Elongin A3 family member D" A6NLF2 18 46962768-46964408 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 37 "brain: 3.4;choroid plexus: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 1.4 0.0 2.2 0.0 0.0 1.2 1.4 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.0 0.0 3.4 1.9 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.2 1.4 1.0 0.9 3.4 1.9 2.4 0.8 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ELOA3CP ELOA3C ENSG00000275553 "Elongin A3 family member C, pseudogene" 18 46968695-46969912 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 28 "brain: 2.2;choroid plexus: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049178, HPA050086, HPA053158" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 88: Choroid plexus - Transmembrane transport" Nucleoplasm Cytosol "HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 1.2 0.0 1.7 0.0 0.0 0.6 1.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 0.6 1.1 0.8 0.7 2.0 2.2 2.0 0.9 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012254.6 ENSG00000288607 "Elongin A3 family member B" Q3SY89 18 47022287-47023927 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 34 "brain: 3.4;choroid plexus: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 2.0 0.0 2.7 0.0 0.0 0.9 1.3 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 3.4 3.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.7 0.9 1.3 1.1 1.1 3.4 3.2 2.7 1.8 2.3 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012254.7 ENSG00000288631 "Elongin A3" Q8NG57 18 47028202-47029842 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 44 "brain: 3.9;choroid plexus: 4.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048971, HPA049178, HPA050086, HPA053158" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA NA Nucleoplasm "Nucleoli, Cytosol" "HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " 0.0 0.0 2.0 0.0 2.8 0.0 0.0 1.5 1.8 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 0.0 0.0 0.0 0.0 3.9 3.8 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.8 1.5 1.8 1.6 1.9 3.9 3.8 2.7 1.1 3.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ELOA2 "HsT832, TCEB3B, TCEB3L" ENSG00000206181 "Elongin A2" Q8IYF1 18 47032572-47035621 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 33 "brain: 2.3;choroid plexus: 3.4;testis: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041009, HPA043501, HPA048971, HPA049178, HPA050086, HPA053158" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Cytosol "HPA041009: AB_10959881, HPA043501: AB_10960403, HPA048971: AB_2680578, HPA049178: AB_2680664, HPA050086: AB_2681009, HPA053158: " "unprognostic (2.38e-1)" "unprognostic (4.47e-1)" "unprognostic (2.54e-4)" "unprognostic (2.39e-1)" "unprognostic (8.75e-2)" "unprognostic (5.34e-2)" "unprognostic (3.64e-1)" "unprognostic (5.25e-2)" "unprognostic (1.81e-1)" "unprognostic (1.38e-2)" "unprognostic (3.97e-2)" 0.0 0.0 1.0 0.0 2.0 0.0 0.0 0.8 1.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 2.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 4.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.0 0.8 1.1 0.7 0.6 2.0 2.3 1.9 0.9 1.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 IER3IP1 ENSG00000134049 "Immediate early response 3 interacting protein 1" Q9Y5U9 18 47152834-47176364 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Diabetes mellitus, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 357.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA010027 Supported Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA010027: AB_1079098" "unprognostic (6.13e-2)" "unprognostic (2.96e-2)" "unprognostic (3.82e-2)" "unprognostic (1.45e-2)" "unprognostic (1.11e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (6.47e-6)" "unprognostic (9.86e-2)" "unprognostic (5.13e-2)" "prognostic favorable (8.59e-4)" "unprognostic (6.44e-2)" "unprognostic (6.24e-3)" "unprognostic (1.53e-3)" "unprognostic (8.55e-2)" "unprognostic (2.71e-2)" "unprognostic (8.75e-2)" "unprognostic (1.27e-3)" 13.7 17.2 8.1 11.8 8.2 14.5 14.2 11.1 10.0 10.5 11.2 14.1 16.9 11.2 10.9 12.0 9.0 10.2 17.0 8.2 9.1 31.4 19.5 12.3 11.4 8.8 8.9 11.6 13.7 19.2 15.5 10.9 9.0 13.9 13.0 14.1 15.0 7.9 31.1 13.8 15.7 9.5 8.0 11.1 15.9 9.3 8.9 11.1 15.9 21.7 10.6 13.9 11.0 8.9 27.1 15.3 22.9 20.5 30.5 33.8 15.9 62.7 30.5 30.6 32.2 12.5 22.7 26.5 19.3 28.1 25.0 32.3 21.8 22.1 33.2 43.5 19.5 23.3 23.0 38.2 32.5 70.5 33.2 26.8 27.7 27.6 20.6 28.9 26.7 23.7 19.4 39.7 33.0 15.0 25.1 33.7 11.6 11.5 18.4 24.7 35.9 37.9 31.2 26.0 26.4 29.4 21.5 18.1 38.8 16.4 18.0 40.1 38.7 45.2 23.3 22.0 34.7 56.9 66.4 27.9 35.3 44.4 37.2 15.9 17.2 16.1 25.0 16.6 22.2 18.9 21.1 21.5 16.6 20.9 19.6 20.8 1.9 17.3 17.5 34.5 23.6 19.3 8.1 8.2 11.1 10.0 8.2 9.1 8.8 8.9 9.0 8.0 8.9 8.9 80.8 86.6 51.8 7.8 58.9 0.0 64.6 0.0 73.4 48.0 96.0 51.4 63.1 97.2 19.2 51.5 8.4 104.9 61.3 35.6 140.8 124.3 18.4 49.5 47.7 70.8 37.6 51.3 15.7 138.9 126.3 76.2 57.6 55.6 13.9 40.0 83.6 138.8 108.9 40.4 17.4 69.1 0.0 63.6 0.0 13.3 84.8 54.8 0.0 12.2 79.4 69.6 86.5 16.1 19.1 139.3 50.1 48.5 158.8 117.3 125.0 357.0 26.2 48.0 52.6 40.4 61.6 163.3 158.9 88.1 0.0 177.2 54.4 36.7 62.2 109.4 SKOR2 "CORL2, Fussel-18, FUSSEL18" ENSG00000215474 "SKI family transcriptional corepressor 2" Q2VWA4 18 47206169-47251660 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Group enriched" "Detected in some" 4 "Bipolar cells: 1.8;Spermatocytes: 2.5;Spermatogonia: 5.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "NTERA-2: 3.9" "Region enriched" "Detected in single" 5 "cerebellum: 2.4" "Not detected" "Not detected" HPA046206 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA046206: AB_2679588" "unprognostic (1.53e-1)" "unprognostic (1.93e-1)" "unprognostic (1.92e-1)" "unprognostic (6.31e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.8 0.6 1.8 0.2 1.1 2.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025507, HPA067203, CAB073546" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Cytosol" "CAB025507: , CAB073546: , HPA067203: AB_2685803" "unprognostic (1.55e-1)" "unprognostic (2.49e-1)" "unprognostic (1.43e-2)" "unprognostic (9.82e-3)" "unprognostic (9.88e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.91e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-3)" "unprognostic (6.46e-2)" "unprognostic (4.91e-2)" "unprognostic (9.20e-3)" "unprognostic (2.68e-1)" "unprognostic (6.13e-2)" "unprognostic (3.20e-2)" "unprognostic (6.28e-2)" 48.6 52.6 38.0 38.6 42.4 37.5 46.5 46.2 36.7 43.2 35.6 47.5 36.7 38.6 41.0 55.0 46.8 39.6 53.8 32.9 48.6 43.3 35.6 46.7 44.5 50.2 43.2 52.5 40.4 44.6 20.3 42.7 51.9 36.4 48.7 70.5 36.7 44.8 57.4 34.0 37.4 47.9 47.8 47.5 45.2 51.5 42.4 72.4 75.7 55.5 55.2 53.8 31.1 59.4 81.1 113.7 68.0 66.2 106.1 128.5 77.4 86.1 102.7 87.9 101.8 43.8 75.6 124.8 60.3 110.0 123.0 86.6 77.2 96.1 116.9 136.4 39.3 106.4 164.4 71.9 123.2 149.6 104.1 95.8 121.4 75.5 172.9 102.1 98.6 99.7 50.3 101.6 109.6 52.7 103.4 71.6 33.6 4.4 26.7 74.4 98.9 85.9 197.8 137.2 62.8 73.3 103.7 70.1 85.7 65.8 53.5 97.7 111.4 129.5 74.2 35.6 63.6 99.0 102.7 108.3 89.6 99.9 97.1 58.8 33.6 38.7 23.8 38.5 29.8 16.7 32.3 29.9 32.8 13.9 35.3 27.6 34.1 38.6 33.0 23.3 40.5 31.6 38.0 42.4 46.2 36.7 32.9 48.6 50.2 43.2 51.9 47.8 42.4 59.4 55.0 44.8 36.1 55.8 36.3 54.4 44.1 38.3 54.1 48.0 44.2 30.2 49.2 41.5 45.5 77.3 212.7 48.2 53.0 42.8 39.2 36.5 68.1 58.6 53.0 53.1 51.0 36.4 63.4 43.5 40.3 40.5 44.4 68.1 21.5 80.0 56.4 29.6 43.9 35.3 50.5 46.1 38.7 57.3 41.8 131.9 41.7 48.7 51.6 104.9 63.9 44.8 72.1 96.0 130.0 44.0 31.6 53.4 34.5 66.1 37.9 39.5 41.8 88.1 32.9 53.5 39.6 37.2 39.4 59.2 61.8 69.5 47.4 41.7 42.3 77.2 ZBTB7C "ZBTB36, ZNF857C" ENSG00000184828 "Zinc finger and BTB domain containing 7C" A1YPR0 18 48026672-48410752 "Predicted intracellular proteins, Transcription factors" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Basal squamous epithelial cells: 45.5;Distal enterocytes: 52.5;Excitatory neurons: 48.8;Gastric mucus-secreting cells: 49.5;Oligodendrocyte precursor cells: 51.3;Squamous epithelial cells: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 4 "RT4: 42.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (1.32e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.59e-4)" "unprognostic (2.83e-3)" "unprognostic (6.60e-2)" "unprognostic (2.91e-3)" "unprognostic (8.57e-2)" "unprognostic (2.63e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "unprognostic (1.54e-1)" "unprognostic (1.05e-2)" "unprognostic (2.71e-1)" "unprognostic (5.52e-3)" "unprognostic (3.85e-3)" "unprognostic (2.89e-2)" 5.3 11.2 7.8 2.0 3.9 0.4 6.1 3.6 5.4 8.4 0.0 14.5 1.8 1.7 17.2 40.8 14.0 3.4 1.6 4.6 8.1 1.9 0.9 4.5 0.6 7.6 6.6 6.5 1.0 5.2 1.8 3.7 4.3 3.2 13.4 6.3 14.7 3.9 1.7 22.4 2.9 2.1 5.0 9.2 13.8 9.2 14.7 0.3 16.7 1.6 3.8 11.0 19.5 4.8 0.0 0.0 1.5 1.2 0.2 0.4 0.8 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.5 0.0 1.7 2.7 0.1 0.4 0.2 0.3 1.3 0.2 3.2 0.1 0.0 0.0 0.4 0.1 0.7 0.2 0.4 0.0 0.0 1.2 0.0 0.1 0.6 0.7 1.7 0.5 0.5 8.6 0.0 0.1 0.0 9.7 1.3 42.7 5.4 6.9 0.6 0.3 0.0 1.4 0.9 0.0 0.0 0.1 0.6 0.5 0.0 0.1 0.2 0.0 2.7 0.1 0.2 1.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 7.8 3.9 3.6 5.4 4.6 8.1 7.6 6.6 4.3 5.0 14.7 4.8 0.5 6.4 1.5 47.0 0.1 6.1 5.3 11.6 45.5 1.2 6.0 8.4 3.1 12.8 9.5 1.8 0.0 13.7 0.1 52.5 0.0 1.0 9.6 4.8 1.8 2.9 4.8 0.0 48.8 4.0 0.8 3.4 49.5 6.7 0.0 1.0 0.0 0.6 1.5 1.7 7.0 30.8 6.1 2.1 0.8 4.4 3.7 0.4 3.6 22.5 0.1 1.0 0.0 51.3 2.1 1.2 14.6 12.0 0.0 7.5 3.5 0.0 7.6 2.5 13.1 8.8 11.9 0.9 0.9 96.9 8.8 12.6 0.2 6.6 18.3 13.7 CTIF KIAA0427 ENSG00000134030 "Cap binding complex dependent translation initiation factor" O43310 18 48539031-48863217 "Predicted intracellular proteins, Transporters" "Nonsense-mediated mRNA decay, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Excitatory neurons: 76.4;Inhibitory neurons: 80.6;Oligodendrocyte precursor cells: 75.9;Oligodendrocytes: 59.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016865, HPA024801" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA016865: AB_1852311, HPA024801: AB_1852312" "unprognostic (5.84e-2)" "unprognostic (5.86e-2)" "unprognostic (2.27e-2)" "unprognostic (1.23e-2)" "unprognostic (2.06e-1)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" "unprognostic (8.86e-2)" "unprognostic (1.95e-3)" "unprognostic (2.77e-3)" "unprognostic (1.35e-1)" "prognostic favorable (3.18e-4)" "unprognostic (1.95e-1)" "unprognostic (1.99e-1)" "unprognostic (2.34e-3)" "unprognostic (7.33e-3)" 35.3 20.0 15.7 3.3 13.9 2.0 24.3 10.7 23.2 14.0 0.0 26.0 2.5 21.5 2.6 11.4 16.3 7.5 24.8 16.0 15.5 11.1 24.8 14.3 1.3 20.7 17.4 28.0 9.8 4.6 12.4 4.3 23.3 13.9 1.6 7.4 11.0 5.4 15.8 14.0 9.9 7.0 9.1 6.7 19.6 7.3 19.0 1.4 10.7 4.3 1.0 26.1 12.6 16.7 3.2 3.4 4.5 5.8 11.3 6.0 2.5 15.9 13.2 12.4 11.2 3.5 1.9 0.0 3.5 22.0 5.2 6.7 3.3 9.0 5.3 0.0 2.7 1.4 7.9 8.4 21.6 2.6 4.5 8.4 14.5 7.8 13.8 8.9 8.9 4.1 4.0 9.8 8.0 1.7 0.9 2.0 2.2 3.4 2.8 1.6 5.2 4.2 3.7 4.3 9.6 9.7 5.6 6.0 4.5 3.8 3.8 3.1 18.1 11.4 10.5 3.4 2.9 3.3 4.2 0.0 10.1 1.6 5.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 13.9 10.7 23.2 16.0 15.5 20.7 17.4 23.3 9.1 19.0 16.7 7.3 35.3 3.7 94.7 1.9 3.3 2.1 3.5 2.8 25.6 11.2 8.4 16.0 5.7 5.6 7.3 16.7 1.9 0.8 4.6 7.9 5.1 11.1 1.7 7.7 8.5 3.5 0.4 76.4 4.8 2.8 13.1 7.1 3.6 4.5 19.5 7.5 23.0 4.2 11.8 80.6 3.5 4.1 6.4 2.7 19.3 25.1 5.0 3.6 30.0 1.5 3.6 3.1 75.9 59.7 5.7 2.7 50.8 4.8 3.0 5.9 5.8 4.7 8.8 6.6 8.8 9.4 2.3 1.8 3.5 2.3 1.2 0.7 34.7 3.3 3.3 SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48952052 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 54.5;Distal enterocytes: 56.6;Hepatic stellate cells: 71.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.1;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026212, HPA028897" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "CAB026212: , HPA028897: AB_10600811" "unprognostic (1.63e-1)" "unprognostic (3.72e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (5.61e-4)" "unprognostic (8.15e-2)" "unprognostic (5.35e-1)" "unprognostic (2.76e-1)" "unprognostic (6.02e-2)" "unprognostic (2.37e-1)" "unprognostic (1.87e-2)" "unprognostic (2.70e-1)" "unprognostic (2.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-2)" "unprognostic (4.44e-1)" 17.9 5.9 7.1 8.6 7.3 17.8 14.5 12.0 7.3 17.4 9.6 12.7 10.3 11.2 2.9 4.8 8.2 10.2 46.1 5.4 5.1 11.6 8.6 21.9 5.8 10.9 8.7 7.5 5.3 12.3 6.6 18.9 8.5 11.3 11.9 3.2 6.3 8.6 10.7 8.3 15.0 9.3 10.0 5.9 12.5 1.3 7.9 3.7 16.6 6.7 5.2 13.3 12.2 8.4 3.7 2.8 2.8 8.3 14.3 5.0 21.1 18.6 7.1 6.5 3.1 1.0 5.3 0.3 32.2 13.1 6.0 19.2 6.1 5.8 3.6 38.4 9.4 0.3 10.5 6.9 2.1 6.9 18.6 5.1 4.8 7.8 7.8 32.2 1.1 0.6 6.6 25.9 9.1 1.2 0.0 1.9 17.3 27.7 1.1 2.1 2.5 9.0 9.1 4.2 4.8 10.3 8.0 3.5 6.6 21.2 3.3 5.6 17.3 18.5 9.9 5.3 16.5 13.4 7.1 2.0 8.1 4.9 3.1 4.1 0.1 5.6 0.8 0.5 0.6 0.1 0.8 0.7 0.1 0.0 0.2 0.5 0.0 1.7 0.1 0.0 1.2 0.2 7.1 7.3 12.0 7.3 5.4 5.1 10.9 8.7 8.5 10.0 7.9 8.4 30.4 54.5 9.4 3.9 7.0 12.9 3.5 7.2 14.2 6.1 14.7 10.3 9.7 1.5 11.2 11.0 6.2 9.9 43.7 56.6 9.8 14.4 0.2 43.2 30.5 25.0 12.7 0.0 6.5 13.9 3.3 15.5 8.2 45.9 18.9 4.0 71.4 3.1 8.9 0.0 5.0 19.1 2.0 23.3 8.9 1.1 1.5 14.7 0.0 19.7 8.2 1.4 11.3 5.5 16.3 31.5 17.3 3.4 13.8 3.0 28.7 7.1 3.3 2.5 6.6 11.3 14.1 0.1 0.6 14.2 11.8 12.9 25.2 1.3 12.4 2.6 DYM "DMC, FLJ20071, SMC" ENSG00000141627 Dymeclin Q7RTS9 18 49036387-49461347 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 113.6;Early spermatids: 353.4;Excitatory neurons: 173.2;Inhibitory neurons: 204.1;Late spermatids: 176.1;Microglial cells: 149.9;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 299.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043551, HPA049187" Approved Supported "Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus" "HPA043551: AB_2678547, HPA049187: AB_2680668" "unprognostic (1.88e-2)" "unprognostic (1.23e-1)" "unprognostic (3.12e-3)" "unprognostic (1.33e-2)" "unprognostic (1.95e-1)" "unprognostic (1.59e-1)" "unprognostic (1.85e-3)" "unprognostic (1.77e-1)" "unprognostic (1.72e-1)" "unprognostic (8.30e-3)" "unprognostic (2.53e-2)" "unprognostic (2.58e-2)" "prognostic favorable (2.76e-5)" "unprognostic (3.89e-1)" "unprognostic (1.69e-1)" "unprognostic (4.26e-3)" "prognostic unfavorable (5.26e-5)" 17.9 19.2 17.3 14.8 19.6 24.0 23.3 24.9 20.4 24.9 24.4 20.7 15.8 19.8 20.2 25.3 18.6 17.7 21.1 16.7 20.4 21.1 19.7 15.7 17.0 22.8 21.1 29.4 80.7 28.6 9.9 14.6 24.5 20.6 16.8 36.0 36.6 22.0 49.6 18.2 14.1 25.1 19.0 12.7 16.6 44.0 19.1 33.0 32.6 46.0 20.7 23.2 22.3 23.9 32.9 19.8 30.6 47.0 56.9 63.9 24.1 32.2 42.1 37.7 36.8 14.6 20.7 102.1 27.8 60.1 27.9 41.0 48.1 42.1 46.0 38.6 24.7 23.8 16.9 43.4 56.7 83.5 41.5 50.1 49.1 44.1 112.7 63.3 59.0 51.6 25.7 60.5 30.4 35.0 56.5 35.5 9.8 27.1 15.2 29.2 39.2 48.3 34.8 37.2 56.5 36.5 21.9 26.1 30.2 34.5 36.7 29.8 32.6 35.6 16.9 15.5 18.9 67.8 52.7 57.4 19.1 51.6 40.5 20.9 26.9 32.7 20.2 23.4 27.2 17.0 19.3 18.7 29.2 13.9 19.6 15.2 11.9 30.6 20.6 8.4 21.4 21.4 17.3 19.6 24.9 20.4 16.7 20.4 22.8 21.1 24.5 19.0 19.1 23.9 16.0 6.4 6.9 113.6 29.1 11.6 20.4 8.1 29.0 20.1 17.9 15.4 24.5 17.2 8.4 3.7 6.2 19.5 17.4 10.5 13.7 18.1 353.4 11.6 17.2 16.3 16.2 17.9 173.2 20.3 22.2 20.6 17.3 14.8 16.5 23.3 14.3 11.5 16.7 21.9 204.1 15.1 6.1 23.0 15.1 176.1 27.7 20.5 3.6 149.9 19.7 16.1 24.7 167.9 299.4 14.7 11.4 27.1 23.8 25.0 16.1 22.5 13.4 24.9 13.1 22.4 15.4 49.8 16.2 19.4 11.4 35.2 21.6 18.1 16.2 20.2 C18orf32 FLJ23458 ENSG00000177576 "Chromosome 18 open reading frame 32" Q8TCD1 18 49477243-49487252 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 238.5;Late spermatids: 233.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040921 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Vesicles Nucleoplasm "HPA040921: AB_10795423" "unprognostic (5.83e-2)" "unprognostic (5.48e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-2)" "unprognostic (4.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-2)" "unprognostic (6.36e-2)" "unprognostic (4.36e-3)" "unprognostic (2.58e-3)" "unprognostic (2.76e-2)" "prognostic favorable (8.89e-9)" "unprognostic (1.02e-1)" "unprognostic (7.42e-2)" "unprognostic (1.28e-2)" "unprognostic (4.36e-2)" 41.5 66.7 10.8 5.6 13.8 6.8 39.8 15.3 20.0 34.9 8.3 46.0 6.1 35.6 5.6 32.3 34.5 6.6 59.3 11.3 13.5 79.6 86.8 46.5 7.9 14.8 13.0 38.8 47.0 18.5 67.9 6.9 14.0 39.4 10.2 24.6 43.7 8.4 37.9 27.8 39.9 7.3 13.4 39.2 58.1 40.9 13.1 8.5 43.9 7.2 10.4 38.8 32.6 18.7 4.3 3.2 14.4 13.3 12.3 8.8 8.6 5.5 7.6 6.0 6.8 0.5 3.7 4.9 8.6 7.9 9.0 11.1 5.1 10.6 12.6 11.3 4.1 4.2 2.3 5.4 11.2 5.1 11.2 9.9 21.0 5.0 6.1 16.0 12.2 10.1 4.1 11.4 9.9 1.9 4.6 2.5 4.7 4.9 5.9 4.0 3.6 3.8 7.1 5.0 10.7 12.3 5.1 3.4 4.4 19.8 3.1 2.3 13.1 9.6 5.0 1.7 6.9 13.4 24.1 9.1 5.2 5.9 7.1 27.4 8.4 25.8 8.4 8.8 8.7 8.9 6.9 7.7 6.6 7.4 6.6 8.4 41.4 6.2 11.3 9.5 8.2 10.3 10.8 13.8 15.3 20.0 11.3 13.5 14.8 13.0 14.0 13.4 13.1 18.7 20.2 44.8 29.2 0.0 50.8 5.5 4.6 21.2 39.3 35.0 26.2 15.0 5.5 31.5 22.4 23.9 43.8 22.9 33.8 92.9 39.2 87.5 238.5 38.1 21.0 17.5 95.5 20.2 0.0 82.7 17.7 28.7 63.2 30.3 45.6 5.3 23.6 40.4 22.1 18.5 0.0 57.3 32.6 38.0 12.0 233.1 17.1 48.1 23.2 0.0 73.9 41.4 34.0 0.0 0.0 92.3 77.5 10.1 83.0 5.6 92.7 57.2 42.4 36.3 19.7 10.3 22.7 12.7 13.9 58.4 7.7 38.7 43.4 4.5 40.8 5.2 RPL17-C18orf32 ENSG00000215472 "RPL17-C18orf32 readthrough" 18 49481681-49492479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 153.8;Alveolar cells type 2: 154.3;Club cells: 96.6;granulocytes: 65.6;Respiratory ciliated cells: 117.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043724, HPA046385" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum, Cytosol" "HPA043724: AB_2678637, HPA046385: AB_2679646" "unprognostic (1.62e-1)" "unprognostic (1.67e-2)" "unprognostic (1.70e-3)" "unprognostic (3.83e-4)" "unprognostic (1.95e-1)" "unprognostic (2.46e-1)" "unprognostic (3.02e-1)" "unprognostic (2.38e-1)" "unprognostic (2.46e-2)" "unprognostic (2.87e-1)" "unprognostic (5.42e-2)" 41.7 77.7 109.4 35.7 111.6 49.1 49.6 117.5 159.2 36.5 113.7 43.7 51.3 32.2 70.3 25.7 31.1 38.6 63.6 106.0 119.4 96.0 85.0 42.2 35.1 116.3 112.8 34.4 51.8 84.3 9.4 35.3 116.2 48.7 41.6 104.7 54.5 34.4 30.1 22.2 48.3 26.7 116.2 35.9 55.7 30.5 112.3 32.8 53.4 38.2 27.2 38.1 5.2 126.1 29.4 25.0 57.3 47.1 55.7 42.3 42.7 34.6 36.6 27.9 32.9 7.7 33.8 21.8 74.0 33.5 30.5 29.6 26.2 29.7 31.1 67.7 20.2 28.0 15.7 28.3 56.6 46.3 59.2 50.5 65.0 22.5 42.3 61.4 35.2 48.6 19.2 60.9 79.2 16.8 41.4 26.8 20.1 28.0 13.0 26.2 21.2 59.4 115.2 34.7 64.5 120.0 22.0 36.8 76.1 41.4 50.3 45.4 33.0 37.4 25.7 23.4 36.8 106.2 60.1 24.9 42.0 26.0 42.7 92.6 30.2 71.3 23.0 41.1 33.4 28.3 27.1 26.5 27.9 20.3 23.3 31.2 85.1 22.3 48.5 38.4 30.9 49.2 109.4 111.6 117.5 159.2 106.0 119.4 116.3 112.8 116.2 116.2 112.3 126.1 0.5 153.8 154.3 0.3 0.4 0.3 0.7 0.3 0.6 0.4 0.5 0.5 0.0 0.0 96.6 0.0 0.0 0.1 0.2 0.2 0.0 0.2 2.8 0.3 0.7 17.8 0.0 0.0 0.1 0.2 0.1 18.5 0.5 0.4 65.6 0.2 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.6 0.0 4.3 0.0 20.9 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.2 0.3 117.3 0.3 0.0 0.2 0.4 1.0 0.5 1.0 0.1 0.3 9.1 0.5 0.1 0.5 RPL17 "L17, rpL23" ENSG00000265681 "Ribosomal protein L17" P18621 18 49488453-49492523 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 2876.9;Squamous epithelial cells: 3332.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA043724, HPA046385" Supported Supported "Endoplasmic reticulum,Cytosol" NA NA 160000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum, Cytosol" "HPA043724: AB_2678637, HPA046385: AB_2679646" "unprognostic (1.11e-1)" "unprognostic (8.77e-2)" "unprognostic (1.33e-2)" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (3.34e-3)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.69e-1)" "unprognostic (3.29e-3)" "unprognostic (2.11e-1)" "unprognostic (4.35e-3)" "unprognostic (2.72e-2)" "unprognostic (3.32e-1)" "unprognostic (1.66e-1)" "unprognostic (6.54e-2)" "unprognostic (2.41e-1)" "unprognostic (9.60e-3)" 1966.5 1982.7 942.7 997.8 948.6 2559.4 2698.3 978.7 1418.8 2426.3 974.0 2075.1 880.2 1747.2 1295.2 2261.4 2040.5 820.1 1417.0 919.9 975.3 1619.5 1470.2 1410.7 2009.4 955.0 944.3 4472.1 4182.0 862.3 1495.0 888.2 967.1 1829.2 1089.6 612.3 1788.1 899.7 1351.1 2405.0 1619.7 912.2 988.0 1850.3 2038.0 574.8 969.5 1637.0 1607.1 868.1 1672.5 1972.7 2087.9 978.7 2205.3 1360.2 1937.9 2315.0 3146.0 6392.2 1829.3 2400.4 2783.7 2229.8 1677.4 1860.7 1039.7 3785.8 1572.2 2399.7 1250.1 2569.5 2690.1 4329.7 2377.4 1547.4 2773.8 1999.8 1500.4 2560.9 2718.4 6578.1 1526.2 6150.1 4787.7 2333.9 5487.0 5189.2 3100.5 2538.6 1995.5 2685.2 2794.0 1781.7 2386.9 4203.2 1993.4 1327.9 1110.7 2333.6 2538.1 4932.3 3037.1 2571.4 1462.8 1741.2 882.6 1827.5 3949.5 2366.9 1726.9 4230.9 2473.3 1633.3 1389.1 815.2 2570.9 2341.0 2404.3 3520.5 1564.3 3936.3 1593.2 312.8 840.7 151.3 1081.4 743.0 2106.6 1907.9 1763.3 1442.8 1305.7 1574.1 1936.2 1697.1 104.4 1431.9 618.7 1427.3 1509.5 2477.8 942.7 948.6 978.7 1418.8 919.9 975.3 955.0 944.3 967.1 988.0 969.5 978.7 104.8 663.4 916.1 0.0 1445.5 701.8 237.9 319.7 2876.9 15.3 704.3 451.7 0.7 348.9 969.4 103.0 10.4 396.5 311.7 386.7 497.0 864.7 195.8 102.2 169.2 426.4 819.2 1193.5 0.0 1630.2 582.5 558.6 1132.5 98.5 998.9 58.9 414.1 217.3 272.3 10.1 0.0 1233.6 81.4 561.1 588.8 452.1 527.2 616.8 291.7 0.0 973.9 42.7 515.9 0.0 0.0 1268.6 909.2 272.3 1659.1 177.3 768.9 648.6 561.5 23.8 249.8 401.7 297.5 100.8 100.5 3332.8 922.5 414.8 1066.7 61.1 1437.8 216.6 LIPG EDL ENSG00000101670 "Lipase G, endothelial type" Q9Y5X9 18 49560699-49599185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "placenta: 149.3;thyroid gland: 242.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Extravillous trophoblasts: 67.9;Glandular and luminal cells: 49.0;Hepatocytes: 78.2" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 20.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 122.6;HaCaT: 189.8;RPTEC TERT1: 122.4;TIME: 247.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA016966 Uncertain "Secreted to blood" NA NA 657000000 810000 "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA016966: AB_1852893" "unprognostic (2.20e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" "unprognostic (4.25e-3)" "unprognostic (6.38e-2)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" "unprognostic (4.55e-3)" "unprognostic (9.93e-2)" "unprognostic (1.44e-1)" "unprognostic (6.44e-2)" "unprognostic (8.74e-2)" "unprognostic (2.98e-1)" "unprognostic (8.68e-2)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (1.35e-1)" 4.6 0.2 0.9 16.3 0.6 0.3 1.0 4.0 2.6 0.9 1.7 5.9 6.4 1.4 2.9 1.3 0.5 14.0 1.2 3.2 0.7 6.7 34.7 7.2 1.8 2.8 2.8 0.2 1.9 0.2 0.4 149.3 1.6 1.5 7.2 4.9 0.5 20.9 2.5 1.4 7.2 7.7 1.4 0.4 1.7 7.0 3.7 1.9 242.5 0.1 1.7 14.4 0.6 1.2 2.2 0.3 53.6 122.6 0.5 0.1 0.9 0.6 5.8 0.0 0.1 54.5 19.6 0.2 29.7 0.0 37.2 189.8 8.1 39.0 0.0 0.6 0.3 0.1 0.2 0.3 8.1 0.1 0.8 5.4 43.0 19.1 36.8 0.3 28.0 0.2 0.3 0.3 0.0 0.0 0.0 0.2 8.1 1.4 0.5 0.1 0.0 3.0 122.4 14.8 0.8 0.1 1.0 1.4 0.1 6.9 0.2 0.2 247.4 0.2 0.1 0.1 0.6 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 4.0 2.6 3.2 0.7 2.8 2.8 1.6 1.4 3.7 1.2 0.3 0.0 1.1 0.7 0.3 1.8 5.6 3.3 0.0 0.6 2.8 1.9 1.8 24.3 3.5 14.7 60.5 5.5 0.1 9.3 0.0 3.3 8.4 19.1 8.3 7.9 13.8 0.0 0.2 1.4 67.9 6.0 2.6 49.0 0.0 11.5 5.3 78.2 1.8 0.0 0.3 5.3 2.0 1.9 0.0 8.1 0.3 0.8 1.8 2.8 0.7 1.1 0.0 1.0 0.2 12.8 2.7 0.0 0.3 10.6 10.1 1.3 0.5 2.9 0.0 1.0 2.0 1.4 0.9 0.4 2.6 19.4 1.1 0.1 11.2 11.4 ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1011.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 331.1;Hepatocytes: 810.5;Proximal tubular cells: 708.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042303 Approved Supported Mitochondria NA NA 3800000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA042303: AB_10794046" "unprognostic (7.94e-2)" "unprognostic (3.14e-2)" "unprognostic (2.20e-3)" "prognostic unfavorable (8.53e-4)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (7.63e-2)" "unprognostic (1.70e-1)" "unprognostic (7.97e-2)" "unprognostic (8.03e-3)" "unprognostic (1.72e-1)" "unprognostic (3.84e-1)" "prognostic favorable (1.36e-10)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (8.26e-3)" "unprognostic (3.41e-1)" 126.3 74.2 56.9 44.4 64.9 32.5 79.1 63.7 63.9 24.9 68.4 168.7 170.0 29.0 29.8 30.3 24.4 46.9 223.7 53.2 59.8 378.2 1011.9 48.9 36.6 65.1 61.4 34.8 54.1 35.1 34.9 29.6 64.0 26.4 109.6 31.9 20.3 34.0 165.3 28.0 165.2 44.5 62.8 33.6 37.4 37.7 64.3 39.9 55.8 236.6 31.9 41.6 28.6 64.2 3.9 70.5 110.0 97.5 129.9 69.5 57.4 35.2 52.4 53.6 41.2 146.3 58.9 61.1 73.5 117.5 56.7 4.8 176.8 21.0 51.4 190.5 50.4 45.5 79.0 171.4 62.5 0.7 78.3 91.7 6.7 84.8 26.2 44.6 90.0 87.7 42.5 54.7 147.5 81.8 2.7 89.7 101.5 24.8 26.7 150.8 233.0 217.6 177.7 2.8 163.4 130.9 2.7 76.2 5.6 82.1 45.7 60.0 48.1 49.8 60.5 67.8 36.4 112.3 139.7 157.3 35.0 85.7 47.1 53.0 87.4 96.1 99.2 106.5 123.0 43.2 58.3 88.7 103.2 36.3 50.2 73.2 8.3 120.0 108.1 50.1 76.4 112.7 56.9 64.9 63.7 63.9 53.2 59.8 65.1 61.4 64.0 62.8 64.3 64.2 28.4 38.5 47.3 11.8 31.4 3.6 14.2 15.5 11.4 6.7 25.0 25.5 189.9 234.4 23.7 55.2 4.2 36.5 48.2 331.1 295.4 148.5 71.2 7.9 33.9 30.0 40.1 53.6 1.7 45.7 56.0 47.3 23.9 7.7 45.1 63.3 41.4 810.5 109.6 1.7 4.6 73.0 24.4 64.8 18.5 153.9 48.1 50.6 19.6 13.1 57.2 62.2 106.1 4.5 8.7 101.8 161.2 37.2 41.2 9.8 226.6 708.0 26.4 29.5 19.7 42.1 34.9 51.1 42.7 11.1 4.8 27.0 52.2 93.0 144.8 9.6 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 CFAP53 "CCDC11, FLJ32743" ENSG00000172361 "Cilia and flagella associated protein 53" Q96M91 18 50227193-50266495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 28.5;testis: 79.6" "Group enriched" "Detected in many" 14 "Early spermatids: 809.6;Endometrial ciliated cells: 331.5;Late spermatids: 528.4;Respiratory ciliated cells: 216.5;Spermatocytes: 481.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 4.7" "HPA041069, HPA066142" Enhanced Approved Midbody Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Midbody "HPA041069: AB_10805835, HPA066142: AB_2732739" "unprognostic (1.73e-2)" "unprognostic (1.13e-2)" "unprognostic (5.83e-2)" "unprognostic (3.12e-3)" "unprognostic (3.31e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-4)" "unprognostic (2.90e-2)" "unprognostic (3.68e-2)" "unprognostic (9.75e-3)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "prognostic favorable (5.85e-4)" "unprognostic (3.22e-1)" "unprognostic (1.17e-2)" "unprognostic (4.34e-3)" "unprognostic (4.61e-3)" 0.3 1.2 3.0 0.4 3.4 0.7 1.1 5.0 3.2 2.0 8.5 0.5 0.2 1.1 5.7 0.4 28.5 0.7 0.5 3.1 3.7 2.7 0.4 3.3 0.3 6.8 7.8 1.0 1.1 2.5 3.3 0.3 6.0 0.9 0.2 3.5 0.6 1.2 2.3 1.0 0.4 0.3 5.3 0.4 0.5 79.6 3.4 0.5 3.9 0.4 0.2 0.6 0.6 5.0 1.2 0.8 0.5 1.0 0.7 1.3 0.9 0.2 0.1 0.1 0.2 0.1 1.0 0.7 0.7 0.3 0.3 0.5 0.3 0.5 0.2 0.5 0.7 0.3 0.3 0.1 0.3 0.5 0.4 0.4 2.0 0.5 4.7 1.1 0.3 1.9 1.4 0.4 0.3 1.2 1.2 0.2 0.2 0.2 0.5 0.1 0.2 1.0 1.4 0.0 0.8 0.6 0.1 0.0 0.4 1.3 0.6 0.1 0.0 0.7 0.5 0.4 0.4 2.1 0.8 0.1 0.7 0.5 0.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.2 0.0 0.2 0.2 0.0 3.0 3.4 5.0 3.2 3.1 3.7 6.8 7.8 6.0 5.3 3.4 5.0 0.6 6.4 4.2 2.6 0.6 0.0 2.0 0.0 1.8 4.3 4.7 3.8 0.4 0.0 21.1 9.2 8.4 1.7 0.2 0.3 9.8 3.4 809.6 331.5 3.8 1.4 0.0 0.4 3.8 0.6 0.5 2.2 2.6 7.9 1.3 1.4 1.8 1.0 0.4 1.7 4.4 0.2 0.0 0.0 0.0 528.4 8.4 1.3 0.0 2.8 1.0 2.7 1.0 3.0 6.5 0.8 0.1 5.7 0.9 1.3 0.8 20.5 216.5 10.5 6.6 2.1 0.7 481.5 32.5 1.3 0.0 0.7 1.0 1.7 0.4 1.1 MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 97.4;Spermatocytes: 136.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "CAB009017: AB_2095559, CAB036003: , HPA068850: AB_2732121" "unprognostic (2.12e-2)" "unprognostic (5.05e-2)" "unprognostic (6.88e-2)" "unprognostic (5.01e-3)" "unprognostic (9.20e-2)" "unprognostic (6.85e-2)" "prognostic unfavorable (5.08e-6)" "unprognostic (5.91e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (1.70e-6)" "unprognostic (7.06e-3)" "unprognostic (7.70e-2)" "unprognostic (7.05e-2)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 28.5 39.8 23.9 26.2 25.9 44.2 29.1 24.8 28.2 32.3 19.3 35.7 24.8 32.1 20.5 39.2 31.6 19.6 35.7 26.7 22.2 32.5 35.7 29.9 30.2 23.1 22.0 34.8 34.5 32.4 42.8 24.6 21.1 33.0 17.7 24.0 30.5 23.5 51.0 43.4 33.7 20.4 19.5 41.0 33.6 88.1 23.1 29.6 35.4 28.6 24.2 35.3 32.2 25.6 30.9 28.6 31.5 35.9 33.2 26.9 33.9 36.2 41.4 49.2 37.7 21.6 23.9 48.5 25.8 35.3 28.8 54.4 36.3 63.4 28.4 54.7 23.2 30.6 43.8 23.1 63.9 74.8 62.1 31.5 100.4 56.2 127.2 31.1 40.9 47.4 39.3 73.8 38.3 28.5 63.3 38.9 29.8 16.1 22.7 57.8 23.3 53.2 24.4 13.8 41.5 39.5 27.0 25.5 33.2 25.4 32.4 67.4 44.7 53.0 24.1 17.3 37.2 135.8 62.2 51.6 34.3 56.8 49.0 16.0 11.2 22.7 15.3 9.7 14.6 11.6 13.5 12.9 11.2 11.4 13.8 11.4 14.5 14.3 7.8 10.2 13.8 12.6 23.9 25.9 24.8 28.2 26.7 22.2 23.1 22.0 21.1 19.5 23.1 25.6 17.7 9.6 24.6 19.6 20.1 22.7 13.9 18.2 23.3 15.1 16.5 14.5 28.1 14.3 20.5 16.5 18.8 31.1 25.0 24.5 13.7 15.7 85.1 17.1 16.1 17.6 13.1 9.7 20.4 13.8 24.2 16.5 28.1 17.3 8.8 17.7 13.9 18.1 18.7 15.2 17.3 19.5 24.4 15.8 11.1 97.4 15.5 17.5 16.0 9.4 15.7 17.4 14.4 12.1 16.4 21.1 24.5 19.2 34.6 14.4 21.3 9.7 16.9 20.3 13.1 14.8 18.9 136.0 32.5 21.6 29.3 51.4 20.0 28.1 18.6 17.0 CXXC1 "CFP1, CGBP, hCGBP, HsT2645, PCCX1, PHF18, SPP1, ZCGPC1" ENSG00000154832 "CXXC finger protein 1" Q9P0U4 18 50282343-50287839 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044511 Supported Enhanced Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA044511: AB_10963081" "unprognostic (4.47e-2)" "unprognostic (1.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.18e-6)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (5.08e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.10e-2)" "unprognostic (1.00e-1)" "unprognostic (3.83e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-2)" 18.1 26.7 24.4 22.8 25.4 45.9 19.3 29.8 30.5 28.0 25.9 23.6 27.3 23.3 10.3 23.6 24.9 17.5 19.9 24.6 24.6 25.5 24.5 19.2 34.3 24.6 24.5 30.0 38.7 20.3 21.0 16.0 25.2 24.4 15.9 13.6 32.4 21.4 20.2 29.5 23.5 14.9 22.8 29.6 25.7 22.8 25.0 30.7 23.2 13.1 21.1 25.6 23.7 26.3 24.6 31.9 33.4 46.9 28.9 16.2 46.9 34.3 28.4 38.5 32.1 21.6 19.6 60.2 17.6 22.0 18.5 44.6 51.6 37.0 21.7 51.9 33.0 57.9 42.3 39.5 19.6 126.4 68.7 19.5 32.9 38.0 51.0 26.0 25.0 58.8 29.9 63.8 27.3 37.7 71.6 67.7 47.8 16.9 22.4 74.5 26.9 56.5 26.8 13.9 48.4 47.2 18.0 17.8 21.6 21.2 22.9 56.9 29.2 45.1 28.4 18.4 29.6 119.1 87.7 52.5 28.4 58.6 35.5 24.7 18.8 34.0 24.0 22.0 25.0 26.9 21.6 23.6 21.9 27.5 23.1 18.9 8.1 22.6 18.8 15.5 26.4 20.6 24.4 25.4 29.8 30.5 24.6 24.6 24.6 24.5 25.2 22.8 25.0 26.3 18.1 19.2 27.4 21.9 27.8 26.8 13.1 21.7 21.1 15.3 20.2 17.4 7.3 18.6 23.8 18.4 14.6 34.5 23.7 31.4 13.7 19.4 13.8 20.9 13.8 18.3 35.3 14.9 10.2 21.8 39.2 16.6 33.1 17.6 8.2 20.5 16.8 15.3 22.0 8.4 8.7 25.0 26.4 20.2 17.2 9.8 19.9 21.0 8.8 7.5 21.3 19.3 43.3 9.5 9.4 21.8 26.1 19.5 41.5 13.3 26.5 14.9 21.4 13.5 6.6 19.5 16.9 49.4 22.1 24.5 30.1 37.1 27.7 18.3 26.5 12.0 SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.0;lymphoid tissue: 4.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 22.3;Extravillous trophoblasts: 9.2;Plasma cells: 10.0;Spermatocytes: 16.7;Spermatogonia: 13.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "Karpas-707: 82.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA045495 Approved Approved Microtubules NA Yes "Cluster 17: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules "HPA045495: AB_10960405" "unprognostic (2.18e-2)" "unprognostic (7.85e-3)" "unprognostic (7.66e-3)" "unprognostic (5.93e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (9.60e-8)" "unprognostic (1.03e-3)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "unprognostic (1.18e-4)" "unprognostic (3.91e-3)" "unprognostic (0.00e+0)" "unprognostic (4.50e-3)" "unprognostic (4.66e-2)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" 0.4 0.5 0.9 2.2 0.8 12.0 0.3 2.5 1.1 0.4 0.8 1.6 1.7 0.6 0.2 2.5 0.2 0.3 0.2 1.0 0.5 0.1 0.3 0.4 4.9 1.0 0.9 0.2 0.4 0.1 0.0 1.6 1.2 0.3 2.1 0.4 0.3 0.1 0.6 1.5 1.4 1.1 0.3 1.3 0.8 4.3 1.3 3.6 0.3 0.2 4.8 0.5 0.7 2.4 27.1 10.8 18.6 19.0 1.2 2.1 9.9 30.7 10.6 29.9 28.5 4.7 10.6 21.1 7.6 11.0 25.8 23.6 25.6 13.0 31.4 34.6 2.6 27.0 5.5 18.3 2.3 42.2 26.8 1.5 1.3 20.7 8.2 3.2 20.0 20.0 30.8 82.6 26.4 5.7 34.6 12.1 14.2 6.5 6.4 17.3 18.3 23.5 8.5 1.6 13.7 10.9 17.2 9.9 13.6 15.3 11.4 20.2 10.1 32.8 19.0 12.8 31.8 27.5 41.6 32.4 18.2 34.9 33.3 0.9 0.4 0.1 0.1 0.1 0.1 0.2 0.1 0.5 0.2 0.3 0.2 0.1 0.6 0.6 0.2 0.2 0.4 0.2 0.9 0.8 2.5 1.1 1.0 0.5 1.0 0.9 1.2 0.3 1.3 2.4 0.2 0.0 2.2 0.0 2.8 1.0 0.2 0.4 0.0 0.4 0.7 0.6 0.4 0.0 0.8 0.0 2.1 4.4 0.7 1.6 0.0 0.1 4.5 0.5 0.7 0.4 1.2 22.3 0.2 0.0 9.2 1.4 0.5 1.1 0.0 4.9 2.2 0.1 5.3 0.0 0.1 2.7 0.0 0.8 0.9 2.2 0.3 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 1.1 0.0 10.0 0.4 0.1 0.1 0.2 0.8 0.0 0.2 1.4 16.7 13.5 3.7 0.3 1.5 1.4 0.5 3.4 1.0 MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.9;parathyroid gland: 51.0" "Cell type enhanced" "Detected in some" "Astrocytes: 202.7;Excitatory neurons: 105.2;Inhibitory neurons: 58.5;Late spermatids: 66.4;Muller glia cells: 62.6" "Cancer enriched" "Detected in many" 4 "glioma: 15.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.3;HeLa: 3.3;NTERA-2: 2.2;SCLC-21H: 11.6;SH-SY5Y: 2.8;SK-MEL-30: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Golgi apparatus" Midbody "HPA007461: AB_1079308" "unprognostic (4.12e-2)" "unprognostic (3.24e-2)" "unprognostic (3.60e-1)" "unprognostic (1.42e-3)" "unprognostic (5.17e-2)" "unprognostic (1.84e-2)" "unprognostic (6.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.24e-2)" "unprognostic (1.61e-1)" "unprognostic (4.38e-3)" "unprognostic (2.16e-1)" "unprognostic (3.44e-7)" "unprognostic (1.96e-4)" "unprognostic (5.99e-4)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" 0.9 26.8 56.5 0.2 79.9 0.0 0.8 56.4 46.0 1.5 28.0 6.8 0.6 0.8 3.1 2.3 1.5 1.8 22.1 41.6 57.5 3.3 4.5 2.3 0.0 65.4 70.0 2.9 1.4 51.0 17.8 2.6 56.7 5.0 0.8 22.6 0.9 9.8 1.5 1.3 1.6 1.8 48.8 0.1 2.1 2.4 81.9 7.3 6.2 1.5 0.0 4.6 1.3 38.7 0.0 0.0 1.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 1.1 1.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.6 2.8 0.0 0.8 1.9 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56.5 79.9 56.4 46.0 41.6 57.5 65.4 70.0 56.7 48.8 81.9 38.7 0.4 9.6 0.0 202.7 0.0 0.0 0.4 0.0 0.0 11.4 0.9 1.1 22.9 1.5 0.0 0.0 0.0 4.6 0.0 0.0 5.9 0.9 30.1 0.0 0.0 0.3 0.0 0.0 105.2 0.0 0.3 1.0 0.0 0.0 0.0 0.7 0.0 1.0 0.4 5.0 58.5 0.0 0.0 0.0 0.0 66.4 0.9 0.1 0.0 7.5 0.0 62.6 0.0 18.6 1.9 0.4 0.0 1.5 0.0 0.7 0.0 0.2 0.0 1.0 0.0 1.0 0.7 0.8 0.6 0.0 0.0 1.8 0.0 0.4 0.0 0.1 MRO "B29, C18orf3, FLJ30140" ENSG00000134042 Maestro Q9BYG7 18 50795120-50825402 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 44.7;kidney: 24.1;testis: 28.9" "Cell type enhanced" "Detected in some" "Astrocytes: 30.0;Granulosa cells: 11.3;Hepatic stellate cells: 37.5;Kupffer cells: 13.0;Proximal enterocytes: 20.0;Proximal tubular cells: 16.0" "Cancer enriched" "Detected in some" 7 "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 2.4;ASC TERT1: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022011 Approved NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022011: AB_2670880" "unprognostic (9.21e-5)" "unprognostic (5.22e-2)" "unprognostic (7.87e-3)" "unprognostic (1.45e-2)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-2)" "unprognostic (5.11e-2)" "unprognostic (3.45e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (4.71e-1)" "unprognostic (5.15e-3)" "unprognostic (1.14e-1)" "unprognostic (3.99e-3)" "unprognostic (6.06e-4)" 2.3 2.5 36.6 0.5 42.7 0.2 0.6 32.5 33.1 0.3 18.4 0.2 8.0 0.2 3.1 0.5 0.3 1.0 3.0 33.3 44.7 24.1 7.2 0.2 0.3 35.9 38.5 3.3 1.8 5.3 1.3 0.7 34.4 0.2 0.2 1.6 0.3 2.2 2.0 0.1 4.7 0.3 33.8 2.2 1.3 28.9 40.8 1.2 6.0 1.3 0.1 0.4 0.2 31.0 0.0 0.0 0.0 0.2 2.4 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.3 0.1 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 36.6 42.7 32.5 33.1 33.3 44.7 35.9 38.5 34.4 33.8 40.8 31.0 0.2 0.0 0.0 30.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.8 1.5 0.0 0.0 2.1 0.0 0.0 0.2 5.9 0.0 0.8 0.2 0.0 0.9 0.0 0.0 1.5 1.0 0.8 0.8 1.1 0.1 0.0 11.3 37.5 4.7 8.4 0.0 1.1 0.1 0.0 13.0 0.3 3.3 1.2 1.8 0.0 3.7 0.0 3.9 1.0 5.0 0.3 0.1 0.0 0.7 0.0 0.1 20.0 16.0 0.0 0.2 0.0 0.4 0.1 1.2 0.5 0.0 0.0 0.1 0.1 4.3 0.6 0.1 ME2 ENSG00000082212 "Malic enzyme 2" P23368 18 50879080-50954257 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 176.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008247, HPA008880" Enhanced Supported Mitochondria NA NA 84000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "HPA008247: AB_1853704, HPA008880: AB_1853702" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (9.57e-3)" "unprognostic (2.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.29e-8)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-2)" "unprognostic (4.75e-2)" "unprognostic (1.43e-2)" "unprognostic (4.27e-3)" "unprognostic (2.30e-1)" "unprognostic (2.47e-1)" "unprognostic (4.09e-1)" 12.1 15.7 12.7 21.9 13.6 15.6 9.3 14.1 16.8 8.9 55.5 30.6 38.3 9.0 8.9 12.8 8.5 12.7 45.0 14.8 15.4 12.6 15.1 11.6 25.8 15.6 16.2 8.0 20.9 32.2 10.0 13.1 16.2 13.8 32.4 14.6 7.2 19.9 26.2 8.8 32.3 18.1 13.9 27.2 26.5 18.8 15.4 21.4 10.9 22.9 22.6 16.8 3.4 14.3 40.5 39.9 52.0 61.0 23.2 25.6 24.2 33.2 24.7 42.2 35.5 18.4 21.8 143.3 12.8 29.7 38.5 32.6 78.1 33.3 48.2 60.0 11.6 36.5 22.8 21.5 68.1 123.9 42.5 16.0 40.3 53.1 85.8 27.8 55.0 83.5 39.9 34.1 29.1 8.4 90.4 12.3 34.8 29.0 15.9 58.0 25.8 41.1 45.9 8.6 63.9 34.0 31.0 18.7 33.0 31.0 14.4 59.0 34.6 30.0 32.7 15.8 44.7 62.9 27.1 70.6 30.2 86.5 32.5 7.5 16.4 20.7 6.5 19.0 5.1 7.1 4.2 7.9 13.3 7.2 3.6 4.5 18.1 9.8 25.7 4.4 4.4 7.4 12.7 13.6 14.1 16.8 14.8 15.4 15.6 16.2 16.2 13.9 15.4 14.3 20.9 9.6 11.9 40.1 32.8 15.2 20.2 13.6 12.5 17.0 10.9 10.0 103.6 11.5 22.6 14.7 14.6 16.7 37.9 39.0 39.2 31.9 18.0 18.5 22.6 18.7 12.0 16.6 35.6 38.6 16.3 19.1 43.3 19.1 16.4 176.4 24.3 9.1 89.7 8.4 45.9 27.3 18.3 93.8 15.1 6.7 11.5 54.5 12.4 47.8 48.3 18.0 48.4 52.3 32.5 35.6 22.3 16.6 61.5 25.0 72.4 17.1 10.6 55.0 6.6 23.0 23.2 59.8 30.6 13.2 10.7 8.6 28.1 22.4 36.5 17.4 ELAC1 D29 ENSG00000141642 "ElaC ribonuclease Z 1" Q9H777 18 50967991-50988121 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040867, HPA066483" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA040867: AB_10697716, HPA066483: AB_2685675" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "unprognostic (6.95e-3)" "unprognostic (1.75e-2)" "unprognostic (8.61e-2)" "unprognostic (5.96e-2)" "unprognostic (3.25e-1)" "unprognostic (3.03e-3)" "unprognostic (5.87e-2)" "unprognostic (2.82e-3)" "unprognostic (3.67e-3)" "unprognostic (6.36e-2)" "prognostic favorable (8.43e-8)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" 5.1 7.2 4.2 5.4 4.4 2.3 6.2 3.9 6.0 5.0 4.8 6.2 5.0 4.4 12.8 4.4 6.4 4.1 3.3 4.4 5.2 8.0 9.9 5.1 6.7 3.8 3.9 5.5 8.7 11.8 5.7 5.6 4.0 6.2 7.0 5.0 6.6 6.1 3.1 4.6 6.5 4.3 3.3 6.9 6.3 7.2 5.2 7.2 10.2 2.8 6.9 4.7 3.4 5.1 9.1 6.1 16.0 13.6 17.5 7.4 6.8 9.8 12.7 9.0 6.3 2.3 7.9 7.0 6.5 9.1 7.2 8.8 5.0 10.3 6.1 15.4 1.3 8.6 2.3 1.6 10.4 22.1 5.8 9.3 8.1 4.8 11.0 7.2 9.5 10.0 8.9 16.9 16.0 4.1 7.8 6.4 8.0 7.6 3.1 8.6 5.6 13.0 10.4 3.8 9.4 10.7 8.2 1.4 15.5 6.6 7.5 16.6 8.4 11.6 6.0 3.4 6.7 15.8 14.4 9.3 10.7 7.3 14.9 5.0 9.6 10.0 15.4 11.5 17.1 18.6 14.7 14.9 15.4 16.8 14.0 18.1 0.9 20.8 11.4 13.0 12.8 10.0 4.2 4.4 3.9 6.0 4.4 5.2 3.8 3.9 4.0 3.3 5.2 5.1 5.9 6.4 6.5 7.2 7.6 2.4 5.6 14.5 4.6 7.3 8.7 10.4 8.6 12.8 8.0 3.7 2.1 23.3 4.0 8.5 19.6 14.6 21.4 8.8 6.3 7.9 10.3 5.5 4.1 13.5 13.3 8.1 3.1 4.8 8.2 11.4 10.0 15.2 15.4 5.0 5.3 8.2 14.2 8.9 2.8 22.8 5.0 6.3 5.4 2.8 10.2 15.8 23.7 7.5 8.4 10.4 9.1 7.2 5.6 8.1 15.9 25.5 11.8 8.2 0.0 8.5 6.4 29.1 12.9 5.6 3.4 18.9 6.8 11.1 10.5 4.9 SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019154 Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Centrosome "HPA019154: AB_1853480" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (1.25e-2)" "unprognostic (4.83e-2)" "unprognostic (1.17e-2)" "unprognostic (4.05e-1)" "unprognostic (7.29e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (2.51e-2)" "unprognostic (1.03e-3)" "unprognostic (4.40e-2)" "prognostic favorable (1.92e-5)" "unprognostic (2.62e-2)" "unprognostic (4.23e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" 16.4 11.8 9.0 10.9 10.3 10.6 17.2 21.7 10.5 18.5 11.2 14.9 11.9 20.6 9.8 15.7 16.3 12.8 14.1 11.7 10.0 16.1 19.1 13.1 12.7 9.0 8.2 24.0 21.4 19.9 11.3 18.9 9.4 21.8 14.3 18.3 14.0 18.0 24.9 14.6 12.1 18.9 8.0 13.9 15.2 14.2 11.9 17.7 21.4 24.9 14.5 13.5 13.1 13.8 16.4 22.5 59.4 16.6 23.9 36.6 31.4 27.7 32.2 39.4 49.6 13.0 3.8 25.9 7.8 25.6 19.6 24.9 33.6 13.2 40.7 19.3 14.8 20.6 20.5 15.9 23.7 34.8 13.1 16.6 21.9 19.1 27.8 37.0 28.7 14.0 21.9 25.8 23.5 9.0 18.8 10.0 31.2 9.1 14.3 23.3 30.6 26.9 18.2 7.4 34.4 20.3 27.0 5.0 18.8 24.8 13.3 19.4 20.0 34.5 13.3 8.8 19.7 30.6 28.6 26.2 21.2 12.8 22.6 0.3 0.6 0.6 1.0 0.4 1.1 0.7 1.0 0.8 1.2 0.9 1.2 1.5 1.0 1.0 0.4 1.0 1.4 0.5 9.0 10.3 21.7 10.5 11.7 10.0 9.0 8.2 9.4 8.0 11.9 13.8 32.5 22.4 29.1 55.2 21.0 25.6 20.9 15.1 18.8 17.1 27.3 20.4 38.8 24.3 19.3 22.0 20.9 20.7 24.0 22.7 11.7 16.9 10.6 30.4 36.6 26.2 39.6 12.4 37.0 12.5 20.6 30.3 28.5 35.2 4.5 132.4 28.5 44.1 15.1 15.2 39.0 32.1 16.2 28.5 20.9 16.2 33.2 21.1 28.4 49.6 16.9 20.4 17.5 41.2 72.5 20.1 21.0 30.5 24.8 36.3 26.7 22.6 22.4 20.0 26.3 32.2 34.2 17.2 18.8 20.9 27.3 12.6 20.1 22.1 24.5 29.7 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 118.4" "Group enriched" "Detected in many" 6 "Early spermatids: 555.3;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavorable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 17.6 13.5 9.1 17.0 9.9 49.4 17.4 12.5 12.3 16.4 9.0 13.5 12.6 17.6 10.4 15.5 14.0 18.6 10.8 10.5 9.8 11.9 14.0 13.7 23.6 10.5 10.0 23.5 14.7 17.9 1.7 16.1 10.6 11.5 14.1 14.8 9.6 12.2 9.7 9.2 13.4 20.1 10.7 22.3 13.3 118.4 9.3 40.9 16.1 17.1 26.6 20.2 2.4 11.6 23.8 19.6 71.2 26.8 27.7 36.8 49.6 32.8 37.4 18.9 22.2 33.6 17.3 53.0 13.2 44.2 30.4 44.6 27.9 42.7 31.0 43.0 12.5 10.7 19.1 29.0 44.5 75.2 22.3 28.2 46.5 26.9 76.4 47.0 41.8 36.0 11.3 95.7 40.0 18.0 63.8 24.3 32.1 13.3 15.0 61.7 36.5 46.7 31.1 9.5 34.8 39.1 30.4 12.4 117.7 54.3 13.5 34.3 43.2 46.3 30.9 15.1 28.1 64.5 12.4 87.2 32.9 31.3 110.7 9.7 1.2 1.5 2.3 1.0 2.0 1.9 2.4 2.4 1.4 1.1 0.9 2.3 0.4 3.4 0.7 1.1 2.0 1.4 9.1 9.9 12.5 12.3 10.5 9.8 10.5 10.0 10.6 10.7 9.3 11.6 25.2 19.2 5.0 6.8 18.6 38.2 10.3 12.4 11.4 12.6 25.9 23.2 14.5 14.3 11.2 3.7 20.9 5.2 56.6 9.0 5.9 12.1 555.3 18.9 22.7 30.0 6.7 7.4 8.0 8.5 7.0 18.2 6.1 34.9 12.7 79.3 10.4 7.6 7.7 11.8 7.9 9.4 12.2 10.9 20.5 514.0 16.1 13.8 19.6 5.6 8.2 10.0 34.0 14.1 13.3 16.5 3.9 15.1 20.6 15.4 9.1 9.3 6.4 14.8 0.0 30.2 17.7 14.4 14.2 18.1 45.9 4.2 24.2 14.9 11.5 19.6 DCC "IGDCC1, NTN1R1" ENSG00000187323 "DCC netrin 1 receptor" P43146 18 52340197-53535903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.9;testis: 7.6" "Cell type enhanced" "Detected in some" "Early spermatids: 205.7;Excitatory neurons: 439.7;Inhibitory neurons: 455.8;Late spermatids: 174.9;Oligodendrocyte precursor cells: 1305.9" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 36.4;U-266/70: 112.5;U-266/84: 57.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055376, HPA069552" Enhanced Approved "Golgi apparatus" NA NA 64000 "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus" "HPA055376: AB_2682798, HPA069552: AB_2686151" "unprognostic (1.96e-3)" "unprognostic (1.69e-2)" "unprognostic (3.13e-1)" "unprognostic (3.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-3)" "unprognostic (2.59e-1)" "unprognostic (5.59e-2)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (8.22e-4)" "unprognostic (4.14e-2)" "unprognostic (1.27e-4)" "unprognostic (7.21e-2)" "unprognostic (1.84e-2)" "unprognostic (1.42e-1)" "unprognostic (2.69e-3)" 0.0 0.6 1.2 0.2 6.3 0.0 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.0 6.9 3.6 0.2 0.0 1.4 0.0 0.7 4.7 0.1 0.3 0.0 0.6 0.0 1.5 0.3 0.1 0.3 0.1 1.2 0.0 0.1 0.1 0.0 0.0 0.2 0.2 7.6 1.1 1.0 0.0 0.0 0.3 0.1 0.1 0.9 0.1 0.1 36.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.1 112.5 57.1 0.0 6.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 6.3 0.0 3.9 6.9 3.6 0.7 4.7 1.5 0.0 1.1 0.9 1.4 0.0 6.0 10.1 0.3 0.0 0.1 0.0 0.0 2.5 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 205.7 0.0 0.0 0.1 0.0 0.0 439.7 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 455.8 0.0 0.0 0.0 0.0 174.9 1.2 0.2 0.0 54.4 0.0 0.2 0.0 1305.9 58.6 0.0 0.0 1.2 5.7 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 2.6 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 MBD2 ENSG00000134046 "Methyl-CpG binding domain protein 2" Q9UBB5 18 54151606-54224669 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 5.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037282, HPA067582, HPA067615" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB037282: AB_477234, HPA067582: AB_2685866, HPA067615: AB_2685872" "unprognostic (4.86e-2)" "unprognostic (7.21e-2)" "prognostic favorable (6.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.36e-2)" "unprognostic (2.47e-1)" "unprognostic (2.38e-3)" "unprognostic (2.35e-2)" "unprognostic (2.71e-2)" "unprognostic (2.36e-3)" "unprognostic (8.04e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (8.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-3)" "unprognostic (5.19e-2)" 26.9 10.5 6.5 19.2 8.9 20.3 19.9 9.5 9.4 16.0 6.5 17.3 12.0 11.3 15.8 29.5 11.3 11.5 14.9 6.8 8.9 16.7 16.9 16.4 32.1 7.6 8.3 11.4 17.4 16.5 9.2 18.8 7.7 13.4 16.4 14.3 19.4 15.1 15.4 25.4 15.5 11.9 7.0 21.2 13.9 31.5 7.9 20.1 31.0 16.8 35.2 21.0 20.1 8.2 29.1 13.2 23.2 11.7 27.3 23.0 22.5 26.5 33.9 30.6 26.6 8.5 15.8 68.7 13.1 42.1 13.5 45.1 20.1 36.6 33.4 50.2 11.1 10.2 20.4 18.3 28.2 32.7 17.7 20.2 40.3 23.5 34.1 20.3 35.9 20.7 8.0 62.0 28.0 14.0 33.1 18.1 24.2 11.3 17.2 21.8 13.9 27.9 44.5 29.9 25.6 10.8 21.0 21.1 14.7 30.3 10.9 16.3 31.2 31.1 14.1 10.9 24.4 65.1 38.3 52.5 27.4 27.4 19.0 0.0 1.4 0.7 0.6 2.6 0.9 0.7 0.7 1.0 0.8 1.3 0.3 0.6 1.2 0.2 5.0 0.7 1.5 0.4 6.5 8.9 9.5 9.4 6.8 8.9 7.6 8.3 7.7 7.0 7.9 8.2 71.1 28.9 21.0 30.3 44.9 49.3 37.3 21.2 13.1 19.3 46.0 35.3 35.8 24.3 23.0 33.1 16.7 14.3 57.6 51.2 7.9 26.3 1.9 62.1 48.9 38.0 16.3 22.7 42.5 58.4 49.4 32.7 21.9 103.3 8.2 32.0 32.2 25.2 30.3 21.9 38.3 35.9 10.2 142.6 38.7 4.8 25.1 82.2 26.6 43.1 69.3 45.9 8.2 32.2 49.5 54.3 28.0 26.4 53.7 51.5 35.7 23.5 30.0 27.0 26.3 39.0 35.2 6.5 6.1 54.6 62.5 18.3 47.7 43.0 38.7 79.5 POLI "RAD30B, RAD3OB" ENSG00000101751 "DNA polymerase iota" Q9UNA4 18 54269517-54321266 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.4;Spermatocytes: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012000, HPA064696" Enhanced Supported "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Cytoplasmic bodies" "HPA012000: AB_1847786, HPA064696: AB_2685325" "unprognostic (1.64e-1)" "unprognostic (5.79e-3)" "unprognostic (9.72e-3)" "unprognostic (4.92e-2)" "unprognostic (3.04e-1)" "unprognostic (4.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.05e-2)" "unprognostic (4.04e-3)" "unprognostic (2.22e-2)" "unprognostic (2.07e-3)" "unprognostic (1.30e-3)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.52e-2)" "unprognostic (6.99e-2)" 21.2 9.2 7.6 7.2 10.6 7.0 18.2 7.4 9.2 13.8 4.8 9.5 7.8 15.0 14.4 7.2 11.3 9.6 10.7 5.7 8.5 14.4 7.5 10.0 9.6 9.5 8.0 16.7 13.4 15.8 11.5 14.8 8.3 14.1 8.6 25.4 8.2 14.6 6.3 7.5 6.6 11.5 8.6 9.4 9.7 38.0 8.5 14.6 31.4 5.6 8.4 9.4 8.7 12.9 12.0 4.3 31.4 19.1 10.3 20.1 10.2 9.7 20.6 10.9 18.0 3.2 11.1 5.6 3.1 14.2 11.1 9.6 7.4 11.1 12.2 13.7 3.7 7.1 5.2 8.3 16.9 11.4 5.5 21.9 16.4 9.5 19.6 24.5 23.4 9.1 4.9 15.6 18.3 9.6 8.2 9.9 10.8 3.0 4.7 5.1 6.4 14.1 12.3 15.9 14.6 14.9 6.9 6.0 10.1 20.2 22.1 5.1 11.3 20.4 5.5 3.1 8.2 12.6 3.0 7.9 14.5 10.0 15.1 4.0 6.3 6.7 4.6 3.5 4.3 5.1 4.8 4.8 6.1 6.5 7.0 4.0 3.9 4.9 3.7 4.8 6.1 3.9 7.6 10.6 7.4 9.2 5.7 8.5 9.5 8.0 8.3 8.6 8.5 12.9 8.7 25.6 16.4 24.5 5.0 2.5 8.0 9.1 10.8 15.3 12.1 10.0 10.5 2.8 9.6 5.5 10.4 33.5 4.7 1.8 9.8 9.0 117.4 14.4 12.3 8.0 6.1 5.0 16.5 6.2 16.6 11.0 9.2 10.3 13.3 13.9 8.9 6.1 9.2 3.3 20.3 4.7 8.2 5.9 2.5 25.4 19.9 6.2 7.2 26.2 8.2 18.7 7.2 28.6 43.5 6.2 2.6 18.0 3.3 4.7 3.7 15.6 20.6 23.6 32.9 13.9 9.6 80.1 31.4 4.9 2.6 27.9 6.4 11.7 4.3 3.1 STARD6 ENSG00000174448 "StAR related lipid transfer domain containing 6" P59095 18 54324358-54357964 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 26.6" "Group enriched" "Detected in some" 53 "Early spermatids: 189.8;Late spermatids: 271.2;Spermatocytes: 103.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.0;Karpas-707: 2.7;U-266/70: 3.2;U-266/84: 1.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (7.81e-2)" "unprognostic (1.50e-1)" "unprognostic (5.56e-3)" "unprognostic (1.70e-1)" "unprognostic (3.25e-1)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (8.98e-3)" "unprognostic (6.98e-5)" "unprognostic (1.90e-1)" "unprognostic (2.33e-3)" "unprognostic (2.68e-1)" "unprognostic (9.97e-2)" "unprognostic (1.91e-3)" "unprognostic (1.16e-3)" 0.1 0.3 0.3 0.0 0.5 0.1 0.1 0.5 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 26.6 0.6 0.3 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.3 0.2 0.1 0.0 0.4 0.1 0.0 0.7 0.1 2.0 0.3 0.1 0.0 0.0 0.2 0.7 0.3 0.5 0.1 0.2 0.1 0.2 0.3 0.7 0.1 2.7 0.3 0.0 0.2 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.7 0.3 0.7 0.7 0.4 0.0 0.1 0.2 0.0 0.2 0.7 0.2 0.5 0.3 0.2 3.2 1.6 0.3 0.9 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.5 0.5 0.6 0.4 1.1 0.4 0.3 0.5 0.1 0.6 0.7 0.3 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 189.8 0.0 0.1 0.2 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.9 0.0 0.0 0.0 0.4 271.2 2.5 0.2 0.0 0.0 0.0 1.3 0.0 2.0 1.6 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 103.9 3.5 0.0 0.0 0.3 0.2 0.0 0.0 0.1 C18orf54 "LAS2, MGC33382" ENSG00000166845 "Chromosome 18 open reading frame 54" Q8IYD9 18 54357906-54385218 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 100.0;Extravillous trophoblasts: 24.0;Late spermatids: 29.7;Oligodendrocytes: 23.0;Spermatocytes: 38.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.8" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040704 Approved Nucleoplasm "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA040704: AB_10959454" "unprognostic (2.96e-1)" "unprognostic (5.58e-2)" "unprognostic (5.29e-2)" "unprognostic (8.63e-3)" "unprognostic (2.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.60e-6)" "unprognostic (1.11e-2)" "unprognostic (7.85e-3)" "unprognostic (2.55e-2)" "unprognostic (5.91e-3)" "unprognostic (1.13e-2)" "unprognostic (3.06e-5)" "unprognostic (2.29e-1)" "unprognostic (4.21e-1)" "unprognostic (1.28e-2)" "unprognostic (7.05e-2)" 2.1 0.6 1.7 2.3 3.5 1.3 1.1 2.6 2.4 1.9 0.6 1.4 0.8 2.3 0.4 1.0 0.9 1.1 0.9 1.5 2.4 0.8 0.4 1.3 3.0 3.4 2.7 1.4 0.2 0.6 0.2 3.1 3.3 0.6 1.3 1.2 0.4 0.8 0.3 1.0 0.8 1.8 2.3 1.7 0.8 17.3 2.6 3.5 0.9 1.2 2.7 1.0 1.0 5.0 10.2 6.6 22.8 11.7 5.8 10.0 8.2 16.0 6.8 15.5 19.6 4.4 5.2 6.9 4.3 5.6 6.4 9.7 16.9 9.3 20.1 26.5 5.2 7.8 7.2 6.1 1.3 9.4 8.0 3.4 1.8 20.9 10.6 6.7 21.6 9.6 7.8 15.6 22.6 3.8 9.7 4.7 12.5 1.6 11.2 7.7 18.3 5.3 7.1 6.9 14.4 7.8 7.0 2.6 4.2 11.7 4.7 6.8 17.5 32.0 13.3 5.3 8.8 9.8 11.8 10.6 8.1 14.5 22.4 0.5 0.2 0.0 0.4 0.3 0.3 0.3 0.3 0.2 0.2 0.4 0.3 0.3 0.0 0.2 1.8 0.1 0.7 0.2 1.7 3.5 2.6 2.4 1.5 2.4 3.4 2.7 3.3 2.3 2.6 5.0 3.9 0.0 0.6 1.6 1.1 0.4 0.7 0.8 0.0 2.2 0.9 0.9 1.5 0.0 0.2 1.8 0.0 0.9 2.3 0.6 0.0 0.2 100.0 1.4 2.3 3.2 0.0 11.2 0.6 0.2 24.0 2.9 0.5 0.8 0.0 14.2 3.6 0.3 2.5 0.0 0.7 0.4 0.0 3.1 2.1 29.7 1.5 1.7 1.8 3.7 1.3 2.4 3.1 4.5 23.0 0.4 0.9 0.7 1.9 0.5 0.2 0.3 0.3 0.9 0.0 2.1 3.0 38.4 14.5 0.8 0.4 2.1 1.2 0.9 1.7 0.8 DYNAP "C18orf26, FLJ39106" ENSG00000178690 "Dynactin associated protein" Q8N1N2 18 54587757-54599493 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "esophagus: 29.3" "Cell type enriched" "Detected in single" 4 "Squamous epithelial cells: 1.7" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA011148 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA011148: AB_1845609" "unprognostic (9.88e-2)" "unprognostic (2.51e-2)" "unprognostic (1.75e-3)" "unprognostic (1.45e-1)" "unprognostic (8.09e-3)" 0.8 0.4 1.7 0.6 1.3 2.2 0.6 2.2 2.4 0.6 0.0 0.6 0.6 1.0 2.1 29.3 0.5 0.6 1.0 1.4 1.8 0.9 0.8 0.5 1.1 0.9 0.4 0.8 0.4 0.3 0.0 0.4 1.2 0.3 0.7 2.6 1.9 0.5 0.8 1.1 0.5 0.8 0.1 2.4 0.4 1.0 1.5 0.3 0.5 0.4 1.9 0.3 0.2 2.4 0.5 0.2 1.3 0.6 0.6 1.4 1.3 0.3 0.5 1.0 1.0 0.7 0.5 0.7 0.5 0.6 1.1 0.5 0.9 0.0 0.5 0.2 0.2 0.2 0.9 0.4 0.5 0.7 0.6 0.6 0.1 0.9 0.3 0.3 0.2 0.6 1.0 12.9 0.1 0.2 0.5 0.4 2.0 0.2 0.3 0.5 1.5 0.6 0.3 0.7 0.5 0.7 0.2 0.3 2.4 0.9 0.4 0.8 2.2 0.4 2.4 0.5 0.4 0.5 0.4 1.0 0.6 0.3 0.3 0.3 0.3 0.6 0.2 0.3 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.8 0.2 0.8 0.2 0.0 0.0 1.7 1.3 2.2 2.4 1.4 1.8 0.9 0.4 1.2 0.1 1.5 2.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 44.1" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Gastric mucus-secreting cells: 178.4;granulocytes: 246.6;Late spermatids: 209.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 63.3;hTCEpi: 46.6;hTERT-HME1: 56.0;U-87 MG: 165.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: AB_1856000" "unprognostic (1.59e-1)" "unprognostic (5.20e-2)" "unprognostic (9.89e-3)" "unprognostic (7.51e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-3)" "unprognostic (6.82e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.39e-2)" "unprognostic (1.20e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (5.75e-1)" "unprognostic (1.29e-1)" 0.3 2.6 7.9 1.1 10.2 1.0 11.9 0.0 11.9 3.0 0.0 4.9 5.1 0.8 0.4 14.0 1.1 3.8 0.1 13.3 5.2 0.3 1.3 7.2 0.5 0.0 0.1 0.2 4.1 2.3 1.0 1.1 0.6 20.5 5.3 1.0 14.0 1.0 0.2 15.6 4.9 0.9 0.1 1.7 44.1 4.5 2.6 1.4 0.3 0.5 5.2 6.2 5.2 3.3 7.8 22.4 0.8 0.0 1.5 19.3 0.0 1.7 13.5 1.8 1.3 0.0 8.6 1.3 0.1 3.9 16.7 14.5 0.2 9.0 0.5 0.0 0.5 63.3 5.0 0.0 2.6 3.4 7.0 15.3 46.6 25.5 56.0 21.1 1.2 0.3 0.0 3.9 16.1 7.9 0.2 7.4 0.2 14.0 14.7 0.0 0.0 0.3 4.1 28.9 0.2 10.3 2.2 13.4 0.0 0.1 8.3 0.3 0.3 18.8 0.6 9.8 2.0 0.4 0.0 0.0 165.2 35.6 0.9 0.6 0.0 0.1 2.2 0.0 0.5 0.0 0.7 1.1 0.0 0.0 0.2 1.0 0.2 2.6 0.0 0.0 0.0 1.6 7.9 10.2 0.0 11.9 13.3 5.2 0.0 0.1 0.6 0.1 2.6 3.3 0.3 48.1 37.6 3.3 0.9 25.6 8.6 18.2 8.0 2.4 59.8 25.3 0.5 8.6 36.9 5.5 2.1 6.5 15.0 5.7 1.9 7.2 259.3 30.9 4.4 1.9 4.2 3.4 101.0 41.0 4.5 2.0 178.4 64.0 246.6 0.4 2.5 0.9 0.6 6.7 75.8 31.3 20.3 0.6 2.7 209.9 2.1 38.1 7.2 2.8 2.1 1.4 29.9 98.5 2.6 34.0 18.6 0.4 3.2 78.9 3.0 0.0 15.8 0.4 6.6 0.3 2.2 7.9 1.4 79.2 49.2 2.9 13.9 0.5 7.9 42.2 CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 24.8;placenta: 32.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 95.2;Early spermatids: 95.4;Pancreatic endocrine cells: 87.9;Paneth cells: 68.7;Proximal enterocytes: 61.1" "Cancer enhanced" "Detected in many" "stomach cancer: 4.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 10.8;HHSteC: 13.6;HSkMC: 14.9;RT4: 10.5;TIME: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Cytosol "HPA040865: AB_2677176, HPA048197: AB_2680310" "unprognostic (1.36e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (5.91e-2)" "unprognostic (2.65e-2)" "unprognostic (6.29e-2)" "unprognostic (2.71e-1)" "unprognostic (1.16e-1)" "unprognostic (1.15e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.77e-2)" "unprognostic (9.71e-2)" "unprognostic (6.12e-2)" "unprognostic (2.38e-1)" 5.5 3.8 1.6 4.1 1.5 0.4 3.4 1.4 2.7 4.2 2.3 18.9 20.2 3.3 0.8 1.8 2.4 5.1 5.7 1.5 3.6 2.8 9.5 13.0 0.8 2.0 2.3 15.7 2.8 0.8 3.6 32.4 2.0 4.2 18.2 0.6 1.8 1.3 1.5 0.9 24.8 2.7 1.2 7.2 14.3 8.8 3.3 0.6 2.6 4.4 1.3 2.3 1.8 1.3 10.8 3.3 0.0 0.0 3.0 8.3 0.0 0.3 4.2 0.6 0.7 5.9 6.2 0.0 7.6 0.0 0.1 0.1 0.7 6.8 0.5 0.0 1.6 0.8 3.6 1.2 13.6 0.0 0.0 14.9 0.0 3.2 0.1 0.0 4.9 0.0 0.0 0.1 0.4 0.8 0.0 0.2 0.0 7.6 3.6 0.3 0.0 0.3 1.2 10.5 0.1 2.5 3.3 1.0 0.1 1.2 0.0 0.0 28.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.6 1.5 1.4 2.7 1.5 3.6 2.0 2.3 2.0 1.2 3.3 1.3 38.5 19.2 10.3 0.3 1.0 0.3 7.4 4.8 1.2 0.1 2.0 1.9 5.5 10.0 13.3 1.8 0.0 2.3 0.3 95.2 1.9 7.2 95.4 15.0 2.5 40.8 6.0 3.6 5.7 35.6 2.7 9.6 38.2 27.1 8.8 2.6 37.5 7.0 0.4 0.0 0.5 21.8 8.2 3.2 1.3 36.7 3.4 0.6 0.0 12.2 1.0 3.3 1.0 0.0 0.1 87.9 68.7 0.7 0.0 32.4 61.1 5.3 4.2 0.2 6.6 0.9 3.0 1.2 2.2 1.1 0.0 6.0 0.4 3.8 20.2 6.4 TCF4 "bHLHb19, E2-2, ITF2, SEF2-1B" ENSG00000196628 "Transcription factor 4" P15884 18 55222185-55664787 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Disease variant, Epilepsy, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adipocytes: 820.0;Endothelial cells: 574.5;Inhibitory neurons: 1177.6;Oligodendrocyte precursor cells: 719.8;Oligodendrocytes: 573.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 65.1" "Group enriched" "Detected in many" 14 "memory B-cell: 173.6;naive B-cell: 146.8;plasmacytoid DC: 559.8" "Group enriched" "Detected in many" 33 "B-cells: 173.6;dendritic cells: 559.8" "Cell line enhanced" "Detected in many" "HDLM-2: 140.4;SH-SY5Y: 157.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020722, HPA025958" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "CAB020722: , HPA025958: AB_1857849" "unprognostic (2.11e-1)" "unprognostic (9.10e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (3.03e-2)" "unprognostic (8.64e-2)" "unprognostic (1.79e-2)" "unprognostic (3.29e-2)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (1.99e-3)" "unprognostic (2.68e-2)" "unprognostic (2.76e-3)" "prognostic unfavorable (9.95e-4)" 20.3 9.6 3.7 12.8 12.5 9.5 11.6 65.1 26.5 28.5 0.0 7.4 5.1 23.0 2.1 9.7 13.4 17.4 17.5 29.8 0.0 4.4 4.4 15.5 14.7 5.5 1.0 25.9 5.8 8.0 6.5 28.9 3.9 6.6 7.9 14.0 6.8 10.2 6.1 6.4 5.0 24.1 2.2 13.1 6.0 15.4 2.4 9.8 13.3 16.7 14.7 13.1 7.3 14.4 0.1 4.1 36.8 11.4 8.5 14.4 0.1 18.4 40.6 13.2 17.2 23.1 3.6 28.8 0.1 41.9 2.7 4.5 17.9 17.1 9.2 140.4 13.9 12.1 0.1 0.0 4.0 5.3 2.8 19.6 5.3 18.5 0.7 9.1 45.8 1.6 19.5 22.0 11.0 0.0 7.6 0.0 10.4 0.1 2.4 41.6 14.9 65.4 0.0 0.9 12.6 157.7 0.0 1.5 0.0 11.1 1.6 1.3 49.1 48.5 17.4 2.1 14.6 16.3 32.2 25.7 11.0 5.2 15.5 0.9 7.4 0.8 0.9 8.3 0.7 173.6 0.2 0.5 20.6 146.8 0.5 0.3 1.8 11.2 7.4 559.8 0.7 11.3 3.7 12.5 65.1 26.5 29.8 0.0 5.5 1.0 3.9 2.2 2.4 14.4 820.0 6.4 13.1 501.1 217.4 117.0 37.8 34.0 80.8 293.0 6.5 23.4 35.5 4.3 32.6 22.0 83.4 1.8 446.8 0.1 0.0 1.5 103.2 17.5 201.4 574.5 5.4 34.2 503.8 7.1 1.5 296.7 1.5 12.2 13.9 105.7 316.3 6.6 39.6 25.2 1177.6 0.3 26.4 112.4 129.2 116.3 205.3 80.4 64.0 474.1 32.7 372.8 13.4 719.8 573.6 2.1 0.1 182.1 131.7 20.8 0.0 2.3 25.9 54.7 236.7 304.5 221.0 8.7 14.5 47.5 84.4 2.6 15.1 164.8 0.2 17.8 TXNL1 "TRP32, Txl, TXNL" ENSG00000091164 "Thioredoxin like 1" O43396 18 56597209-56651600 "Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002828, HPA002829, CAB016446" Supported Supported Enhanced Cytosol NA Yes 1100000 "Cluster 34: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "CAB016446: , HPA002828: AB_1858358, HPA002829: AB_1858359" "unprognostic (2.05e-1)" "unprognostic (2.97e-1)" "unprognostic (3.38e-3)" "unprognostic (4.54e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "prognostic unfavorable (9.62e-6)" "unprognostic (1.83e-1)" "unprognostic (1.03e-2)" "prognostic favorable (6.26e-5)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-3)" "unprognostic (1.24e-1)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (1.51e-1)" 38.3 55.9 45.4 38.6 47.5 83.0 49.1 49.1 63.6 42.5 40.1 41.7 42.1 38.3 66.9 54.2 35.2 40.0 80.0 50.0 50.9 51.7 80.7 30.6 41.2 47.7 47.2 47.1 62.2 51.4 38.2 48.1 49.5 40.5 43.4 77.9 48.5 39.3 149.0 36.5 40.6 43.4 46.2 32.2 46.7 41.9 47.5 48.0 197.9 146.8 49.9 51.8 35.1 54.0 77.7 74.8 99.2 102.8 83.2 121.6 70.2 90.2 91.8 113.4 95.4 67.0 74.2 83.4 78.1 98.4 82.3 93.7 94.4 81.3 116.9 85.7 43.1 114.9 58.3 127.1 98.3 168.9 71.7 92.9 82.4 107.4 97.4 118.8 93.0 62.9 85.5 136.0 116.0 74.4 98.1 109.8 71.9 53.5 79.6 78.2 66.8 145.9 133.0 118.6 81.6 74.5 51.3 70.9 88.1 78.3 77.5 89.1 74.3 118.7 62.9 41.9 89.5 130.8 151.1 130.5 77.2 127.0 89.1 98.5 63.1 48.3 26.9 55.8 37.2 38.9 33.0 35.8 54.8 35.4 32.0 32.9 48.3 43.3 54.9 47.0 42.9 61.5 45.4 47.5 49.1 63.6 50.0 50.9 47.7 47.2 49.5 46.2 47.5 54.0 89.7 57.7 45.9 25.5 80.0 134.3 123.1 177.1 75.7 82.7 89.3 110.4 110.1 67.2 108.3 29.5 139.7 242.3 82.7 72.2 109.5 150.5 246.9 88.0 90.0 84.2 75.9 153.8 43.8 128.3 130.9 86.1 52.0 90.3 53.2 167.5 52.8 78.0 150.1 57.2 43.6 111.6 77.3 97.3 97.0 294.1 77.6 90.5 65.8 15.9 121.8 86.0 78.2 26.2 55.6 139.5 83.7 83.8 88.9 121.2 110.0 144.7 75.1 97.1 65.7 73.0 167.1 204.1 108.0 93.9 126.0 358.6 72.4 171.0 109.7 123.1 WDR7 "KIAA0541, TRAG" ENSG00000091157 "WD repeat domain 7" Q9Y4E6 18 56651343-57029811 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 99.6;Excitatory neurons: 268.8;Inhibitory neurons: 223.0;Microglial cells: 111.5;Oligodendrocyte precursor cells: 146.3;Oligodendrocytes: 244.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042074, HPA051057" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA042074: AB_2677833, HPA051057: AB_2732563" "unprognostic (1.03e-1)" "unprognostic (1.32e-2)" "unprognostic (1.65e-2)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" "unprognostic (3.66e-2)" "unprognostic (1.97e-1)" "unprognostic (3.58e-1)" "unprognostic (7.70e-2)" "unprognostic (9.21e-2)" "unprognostic (2.00e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.13e-5)" "unprognostic (4.80e-2)" "unprognostic (4.52e-3)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" 5.9 7.6 13.2 5.9 14.2 7.2 4.9 7.0 19.8 4.8 3.1 5.4 4.1 4.8 5.3 4.4 4.2 5.3 5.9 16.2 11.1 5.3 7.4 5.0 7.4 14.6 8.8 4.2 4.2 9.2 8.4 4.7 14.7 7.5 4.9 18.8 4.2 5.7 8.2 4.3 4.3 5.6 7.8 6.2 4.9 4.6 9.6 10.3 9.1 9.6 5.8 5.0 4.5 16.0 4.7 7.7 8.7 4.9 13.5 7.8 2.2 9.2 7.8 7.4 8.8 3.1 2.9 13.0 3.6 8.3 6.3 4.9 8.8 7.2 9.2 15.1 5.4 12.3 5.8 2.8 8.1 18.7 15.0 6.7 5.9 9.9 6.6 6.1 9.3 6.1 6.0 17.5 9.3 4.6 13.0 5.5 3.7 2.4 5.1 5.8 6.7 6.3 5.7 8.4 11.3 5.6 6.5 3.1 4.3 7.4 4.9 5.2 8.3 10.5 5.3 3.2 5.0 17.4 14.2 13.9 8.6 9.3 7.2 4.0 3.0 5.5 3.6 4.4 4.5 2.4 4.0 3.7 3.6 2.2 4.2 3.8 2.6 4.6 5.5 1.7 5.2 2.0 13.2 14.2 7.0 19.8 16.2 11.1 14.6 8.8 14.7 7.8 9.6 16.0 8.7 3.2 4.8 99.6 7.5 2.9 1.9 2.3 2.8 24.5 3.4 2.4 12.5 5.7 6.8 0.0 31.3 2.0 7.7 5.8 3.9 3.2 21.0 4.4 6.0 6.6 8.4 8.2 268.8 3.6 1.2 6.3 7.7 3.9 10.8 9.0 9.3 8.9 5.8 26.9 223.0 2.7 0.0 16.2 2.8 7.0 5.6 11.3 0.0 111.5 8.8 7.1 10.3 146.3 244.7 2.6 2.6 8.2 10.1 2.6 4.5 3.2 5.7 26.3 6.6 10.7 5.8 2.0 1.7 5.8 2.4 0.7 9.9 9.3 4.1 1.6 BOD1L2 "BOD1P, FAM44C, MGC33608" ENSG00000228075 "Biorientation of chromosomes in cell division 1 like 2" Q8IYS8 18 57147087-57150410 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 930 "testis: 276.4" "Group enriched" "Detected in some" 5 "Early spermatids: 1765.1;Late spermatids: 4911.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036293 Uncertain NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA036293: AB_10673127" "unprognostic (2.35e-3)" "unprognostic (3.72e-1)" "unprognostic (2.47e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 276.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1765.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4911.3 45.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.1 0.0 0.0 0.0 0.0 13.1 0.0 0.0 585.3 21.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ST8SIA3 SIAT8C ENSG00000177511 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" O43173 18 57352557-57371731 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.7;pituitary gland: 8.1;retina: 7.5" "Group enriched" "Detected in some" 8 "Bipolar cells: 29.9;Excitatory neurons: 74.9;Horizontal cells: 63.9;Inhibitory neurons: 56.7;Oligodendrocyte precursor cells: 22.1" "Group enriched" "Detected in some" 11 "glioma: 0.9;pancreatic cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 26 "NTERA-2: 4.4;SCLC-21H: 8.6;SH-SY5Y: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063398, HPA066783" Enhanced Supported "Golgi apparatus" No NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA063398: AB_2685004, HPA066783: AB_2685721" "unprognostic (1.75e-1)" "unprognostic (7.85e-2)" "unprognostic (1.41e-2)" "unprognostic (5.50e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.82e-1)" 0.0 4.3 8.0 0.0 21.7 0.0 0.0 6.7 15.6 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.9 0.0 12.5 14.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 8.1 0.0 0.0 0.0 0.1 7.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.7 2.1 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 9.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 21.7 6.7 15.6 12.5 14.5 0.0 0.0 0.0 0.0 2.1 4.9 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 29.9 0.0 0.0 1.6 5.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 1.4 2.3 0.0 0.0 0.1 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 63.9 56.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.7 0.0 1.2 0.0 22.1 3.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ONECUT2 OC-2 ENSG00000119547 "One cut homeobox 2" O95948 18 57435374-57491298 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.1;gallbladder: 10.1;intestine: 10.1;liver: 8.5;retina: 5.4" "Cell type enriched" "Detected in many" 5 "Horizontal cells: 964.0" "Group enriched" "Detected in many" 7 "liver cancer: 4.3;pancreatic cancer: 4.3;stomach cancer: 5.4" "Group enriched" "Detected in many" 5 "basal ganglia: 9.1;cerebral cortex: 2.3;hypothalamus: 4.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 20.3;HeLa: 14.1;RT4: 6.7;SCLC-21H: 10.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "basal ganglia: 8.7;cerebellum: 4.7;cerebral cortex: 5.6;hippocampal formation: 3.2;hypothalamus: 2.5" HPA057058 Enhanced Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 20: HeLa - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Actin filaments" "HPA057058: AB_2683323" "unprognostic (3.02e-2)" "unprognostic (5.36e-2)" "unprognostic (9.06e-3)" "unprognostic (3.79e-5)" "unprognostic (1.13e-2)" "unprognostic (4.48e-4)" "unprognostic (2.10e-2)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (4.56e-3)" "unprognostic (8.66e-3)" "unprognostic (1.16e-2)" "unprognostic (5.34e-4)" "unprognostic (3.83e-2)" "unprognostic (2.58e-1)" "unprognostic (1.13e-1)" "unprognostic (3.21e-1)" 0.0 0.1 0.4 0.0 9.1 0.0 0.0 0.8 2.3 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 10.1 0.0 0.3 4.2 0.1 8.5 0.0 0.0 0.6 0.3 0.0 2.3 0.8 0.8 0.0 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 1.2 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 1.4 0.0 3.4 0.0 0.1 20.3 3.1 0.7 14.1 3.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 2.3 4.0 0.7 0.0 0.5 1.9 0.0 0.1 1.6 0.7 0.0 1.2 0.0 1.6 6.7 10.1 1.7 0.1 0.0 0.2 0.1 0.5 0.7 0.0 1.0 1.3 0.2 0.2 0.3 3.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 9.1 0.8 2.3 0.3 4.2 0.6 0.3 0.8 0.0 1.0 0.2 0.3 0.0 0.0 2.3 0.0 0.1 0.2 0.0 0.0 4.5 0.4 1.1 2.8 184.5 0.0 7.3 14.6 0.0 0.0 2.0 0.0 79.7 4.9 0.2 0.1 0.5 8.9 0.0 38.7 8.8 0.1 0.3 0.0 0.3 0.0 0.5 5.3 47.0 1.0 964.0 1.8 0.6 0.0 1.3 0.0 3.2 0.3 0.1 0.0 1.0 0.0 3.0 0.0 3.5 1.0 38.7 3.3 0.0 0.0 0.4 0.1 0.1 0.0 5.6 0.0 0.9 0.7 1.9 2.0 0.0 0.1 0.0 0.1 0.2 0.5 0.0 FECH ENSG00000066926 Ferrochelatase P22830 18 57544377-57586702 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Distal tubular cells: 156.5;Erythroid cells: 479.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 32.7;K-562: 31.4;U-266/70: 33.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044100, HPA048177" Approved NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA044100: AB_2678809, HPA048177: AB_2680300" "unprognostic (2.30e-1)" "unprognostic (3.17e-2)" "unprognostic (4.59e-3)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.86e-2)" "unprognostic (3.34e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-1)" "unprognostic (1.92e-1)" "unprognostic (2.36e-1)" "prognostic favorable (2.38e-10)" "unprognostic (1.10e-1)" "unprognostic (8.30e-2)" "unprognostic (4.05e-3)" "unprognostic (3.58e-2)" 9.3 14.7 5.2 1.9 6.3 39.6 8.8 4.7 6.3 7.8 5.8 10.0 1.8 9.2 2.9 12.0 7.6 2.6 17.0 4.8 5.2 20.9 22.0 6.5 1.9 6.3 5.3 8.4 9.2 4.3 8.9 3.2 7.2 9.5 2.4 3.6 9.0 2.4 32.2 8.4 7.2 2.8 5.3 10.0 8.4 4.7 5.3 5.0 9.7 7.4 1.8 9.9 8.5 9.7 5.3 15.1 4.3 8.2 2.6 7.4 4.2 4.5 3.4 2.9 4.0 7.3 3.0 4.8 4.3 6.8 3.9 3.5 4.2 3.8 3.7 6.6 19.0 29.5 12.8 10.5 4.9 17.7 32.7 5.4 4.0 4.0 1.4 4.2 5.3 8.0 31.4 10.9 2.1 10.1 7.8 3.8 4.3 1.9 8.7 6.3 19.7 4.7 8.6 19.1 2.5 8.4 4.8 7.4 3.4 2.5 4.6 2.8 6.8 3.3 1.9 1.4 3.2 33.4 12.4 6.3 3.5 5.6 3.9 3.7 3.8 8.1 4.5 5.0 3.2 2.4 3.0 4.9 6.6 1.0 2.8 3.3 0.6 6.9 5.2 4.3 3.2 3.8 5.2 6.3 4.7 6.3 4.8 5.2 6.3 5.3 7.2 5.3 5.3 9.7 4.9 6.4 10.6 10.4 5.6 2.5 6.7 8.6 5.2 3.8 7.8 6.1 24.5 15.7 7.2 5.5 4.2 36.6 15.4 6.7 156.5 16.4 0.4 6.6 7.9 7.3 2.4 479.7 20.3 16.3 16.5 10.3 4.6 9.7 16.5 11.8 4.2 26.3 33.4 8.4 14.6 4.1 8.2 10.6 4.9 1.1 9.9 12.7 1.8 12.2 15.4 15.1 9.2 12.1 45.5 12.4 6.4 7.2 12.5 6.5 7.0 18.2 9.8 4.1 0.0 9.0 6.8 4.1 5.5 14.2 3.1 24.2 8.1 19.1 5.7 5.0 NARS1 NARS ENSG00000134440 "Asparaginyl-tRNA synthetase 1" O43776 18 57600656-57622213 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 221.3;Cytotrophoblasts: 116.0;Extravillous trophoblasts: 85.2;Hofbauer cells: 117.4;Syncytiotrophoblasts: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034257, HPA040017" Enhanced Supported Cytosol NA NA 76000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Cytosol "CAB034257: AB_2151043, HPA040017: AB_2676801" "unprognostic (9.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.86e-3)" "unprognostic (1.68e-1)" "unprognostic (2.61e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.23e-7)" "unprognostic (1.78e-1)" "unprognostic (1.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "prognostic favorable (1.73e-7)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" 67.2 65.9 51.7 62.1 53.8 48.8 68.3 58.8 77.7 57.5 60.1 108.7 87.3 52.7 66.5 64.2 58.5 56.0 94.8 53.4 60.4 135.1 75.5 51.7 52.8 59.6 55.6 45.4 63.1 125.3 33.2 56.1 58.5 68.4 99.5 68.2 68.8 65.4 127.2 49.6 72.0 65.5 55.9 46.8 79.4 32.7 63.7 59.1 95.0 130.6 67.3 78.0 41.9 60.1 215.1 133.2 129.6 199.1 172.8 130.7 202.5 302.5 161.7 179.2 215.4 100.3 97.0 270.7 136.2 208.7 172.1 241.7 211.0 191.6 259.0 127.5 75.5 217.8 105.4 171.8 299.9 433.0 212.5 146.0 331.2 233.8 245.8 130.6 154.6 169.4 246.5 201.6 200.9 86.2 172.4 111.9 189.6 145.1 118.6 139.8 154.5 229.9 340.3 224.4 140.9 147.6 153.1 184.0 309.4 137.3 108.8 242.6 179.7 190.5 127.7 78.8 215.8 449.1 559.2 260.3 175.1 285.7 227.7 50.9 108.5 38.8 41.8 92.6 50.9 52.6 43.3 44.7 71.7 51.4 58.2 52.6 34.4 43.6 76.8 64.0 49.4 74.9 51.7 53.8 58.8 77.7 53.4 60.4 59.6 55.6 58.5 55.9 63.7 60.1 26.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.3 0.0 0.0 0.0 0.0 116.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 85.2 23.1 0.0 0.0 0.0 0.0 0.0 0.0 117.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 158.6 3.5 0.0 0.0 0.0 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 NEDD4L "KIAA0439, NEDD4-2, RSP5" ENSG00000049759 "NEDD4 like E3 ubiquitin protein ligase" Q96PU5 18 58044226-58401540 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Excitatory neurons: 280.9" "Cancer enhanced" "Detected in all" "prostate cancer: 29.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "T-reg: 5.1" "Lineage enriched" "Detected in many" 4 "T-cells: 5.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 146.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024618 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA024618: AB_1854362" "unprognostic (2.56e-1)" "unprognostic (2.41e-2)" "unprognostic (1.58e-2)" "unprognostic (3.14e-1)" "unprognostic (3.90e-2)" "unprognostic (1.50e-1)" "unprognostic (2.11e-3)" "unprognostic (2.26e-2)" "unprognostic (9.24e-3)" "unprognostic (4.39e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.55e-15)" "unprognostic (2.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.49e-3)" "unprognostic (4.75e-2)" 11.2 16.8 20.9 6.7 34.4 27.0 25.8 25.1 31.3 7.6 0.7 38.8 18.7 5.3 10.0 12.0 9.1 9.5 26.9 32.3 16.2 53.4 36.5 47.9 4.1 10.9 18.4 6.4 60.5 13.6 28.4 12.0 10.4 64.2 42.8 20.5 27.5 20.4 34.0 11.2 33.8 6.2 8.6 7.9 51.5 7.8 16.7 4.5 17.4 13.1 7.9 19.4 5.9 16.3 70.7 24.5 14.6 20.9 5.1 2.1 49.8 19.2 88.2 48.6 74.6 28.6 37.1 15.1 57.7 7.4 51.3 50.3 19.5 86.1 100.8 34.9 15.5 10.6 14.3 111.3 2.4 0.5 6.0 13.0 54.6 66.4 78.8 39.1 4.0 13.2 18.7 6.3 20.0 16.2 1.0 1.0 12.2 26.7 33.3 14.3 20.1 17.6 47.0 88.7 17.5 5.0 16.1 5.1 146.1 28.3 29.4 5.6 28.8 131.5 38.5 7.5 83.4 8.3 15.3 9.5 27.6 10.8 10.8 0.7 0.3 1.2 0.2 0.3 0.5 0.8 0.6 0.1 0.1 0.3 0.3 0.2 0.2 0.3 0.1 0.1 5.1 0.3 20.9 34.4 25.1 31.3 32.3 16.2 10.9 18.4 10.4 8.6 16.7 16.3 6.0 253.2 144.8 110.4 5.1 112.8 161.2 34.0 86.6 18.1 99.5 65.9 47.8 64.3 112.8 62.5 173.0 13.0 3.6 144.5 49.0 35.7 22.6 64.0 7.3 14.7 45.2 57.9 280.9 49.2 4.7 9.5 114.7 75.0 3.8 4.7 17.5 41.3 7.3 62.2 173.3 201.5 101.7 8.4 8.2 6.6 3.4 13.3 14.2 88.1 7.3 45.2 2.1 11.1 105.0 49.9 145.3 17.7 12.7 126.9 127.3 91.6 72.7 10.0 0.0 34.3 6.0 1.1 12.5 62.3 53.0 80.0 6.6 8.2 72.9 155.5 ALPK2 HAK ENSG00000198796 "Alpha kinase 2" Q86TB3 18 58481247-58629091 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 41.9;skeletal muscle: 38.3;tongue: 33.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 120.4;Cone photoreceptor cells: 47.9;Early spermatids: 15.9;Late spermatids: 24.3;monocytes: 18.1" "Cancer enriched" "Detected in some" 6 "renal cancer: 7.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 51.2;BJ hTERT+: 31.0;fHDF/TERT166: 46.6;U-138 MG: 25.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027377, HPA027976, HPA028084, HPA029801" Uncertain Approved Cytosol NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "HPA027377: AB_10600635, HPA027976: AB_10611246, HPA028084: AB_10601996, HPA029801: AB_10602006" "unprognostic (7.35e-2)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.60e-3)" "unprognostic (2.64e-1)" "unprognostic (8.27e-2)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.20e-5)" "unprognostic (5.27e-3)" "unprognostic (2.50e-1)" "unprognostic (4.73e-2)" "unprognostic (3.20e-2)" 0.8 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.3 0.0 0.9 41.9 0.4 0.0 9.2 4.5 0.1 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 2.1 0.3 0.0 38.3 0.5 1.0 0.1 0.0 0.5 1.7 1.1 0.0 3.5 0.0 33.2 4.4 1.5 0.0 0.0 0.0 13.7 0.9 0.0 0.4 3.4 0.3 51.2 31.0 21.2 18.1 3.4 0.0 0.0 5.2 46.6 2.9 0.0 0.0 0.0 21.5 11.5 0.0 0.0 4.4 1.8 2.7 0.0 0.0 3.0 0.0 6.4 0.2 0.7 0.0 0.0 0.0 0.4 13.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 11.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 8.3 0.0 0.0 0.0 25.3 11.2 3.5 8.7 20.9 19.2 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.2 0.1 4.8 120.4 0.0 0.0 0.0 47.9 0.0 0.1 0.0 1.9 1.5 15.9 0.0 2.3 0.9 0.0 0.0 1.0 0.7 0.0 8.9 0.0 0.1 0.0 4.0 0.4 3.0 0.7 1.7 0.7 0.0 0.0 0.3 3.0 24.3 0.3 2.4 0.0 0.0 18.1 2.6 0.0 0.0 0.8 0.2 2.3 0.0 0.6 0.0 0.3 13.6 0.0 0.9 0.0 3.8 1.7 1.1 0.1 0.0 0.9 0.1 0.3 0.0 0.0 0.0 MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 88.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" Cytosol "CAB004494: AB_627909, HPA048432: AB_2680389" "unprognostic (3.25e-1)" "unprognostic (2.31e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" "unprognostic (1.65e-3)" "unprognostic (4.67e-2)" "unprognostic (6.46e-2)" "unprognostic (4.50e-2)" "unprognostic (3.33e-2)" "unprognostic (4.16e-3)" "unprognostic (3.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.53e-2)" "unprognostic (2.34e-1)" "unprognostic (2.97e-1)" "unprognostic (1.03e-1)" "unprognostic (6.00e-2)" 7.1 2.5 2.9 11.2 2.8 10.5 6.3 4.8 3.6 7.7 4.2 5.1 3.6 5.4 4.2 12.5 5.1 5.8 5.4 3.1 4.1 6.7 6.9 7.3 21.1 3.2 2.6 5.3 4.0 5.3 4.7 4.0 3.0 11.5 5.5 8.7 5.8 3.8 8.3 9.4 7.7 4.2 3.0 11.5 4.6 8.2 4.1 15.6 5.3 2.8 23.1 7.1 9.6 3.6 11.4 16.0 16.8 5.2 3.1 6.7 9.2 19.7 12.1 15.7 12.6 13.8 13.5 27.0 10.3 24.0 11.1 12.0 10.8 7.6 20.8 17.0 6.8 9.7 9.0 21.8 4.0 20.1 11.4 4.0 12.2 11.8 10.4 6.6 3.4 7.7 15.3 42.3 9.6 3.3 4.7 9.7 6.3 4.1 7.1 14.8 11.5 19.7 88.9 2.8 2.5 4.5 11.7 6.0 9.3 12.0 5.1 12.2 5.7 22.6 9.1 7.1 20.8 38.5 54.4 16.3 10.6 15.6 9.9 0.3 0.5 0.2 0.7 0.7 0.6 1.1 1.4 0.8 0.7 2.1 1.0 0.8 0.3 0.5 0.5 1.3 0.8 0.4 2.9 2.8 4.8 3.6 3.1 4.1 3.2 2.6 3.0 3.0 4.1 3.6 35.0 22.4 19.2 24.2 67.8 33.0 32.3 4.8 26.2 14.7 13.6 11.0 14.4 10.0 7.0 11.0 85.5 6.2 53.2 11.1 3.9 16.6 12.7 10.4 17.5 31.1 6.7 0.8 61.3 8.5 6.0 15.7 13.7 24.7 31.7 28.1 10.4 11.1 11.8 55.5 42.9 8.6 8.2 21.0 96.5 8.0 10.2 55.9 12.4 34.7 79.5 26.2 20.6 52.3 11.9 16.2 21.9 7.2 42.2 46.6 8.0 30.7 5.8 18.1 19.7 16.1 12.9 40.1 35.6 25.4 24.7 9.0 55.2 5.7 10.7 38.1 ZNF532 FLJ10697 ENSG00000074657 "Zinc finger protein 532" Q9HCE3 18 58862600-58986480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Excitatory neurons: 86.9;Inhibitory neurons: 90.9;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 178.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 118.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015322 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Golgi apparatus" "HPA015322: AB_2304947" "unprognostic (3.43e-1)" "unprognostic (4.36e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (6.46e-5)" "unprognostic (4.24e-1)" "unprognostic (5.84e-2)" "unprognostic (1.50e-3)" "unprognostic (7.40e-2)" "unprognostic (5.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-3)" "unprognostic (1.90e-1)" "unprognostic (7.60e-3)" "unprognostic (1.06e-2)" "unprognostic (1.85e-1)" "unprognostic (5.53e-2)" "prognostic unfavorable (5.76e-4)" 24.0 12.5 33.5 15.7 53.1 1.4 17.9 73.9 39.8 30.3 12.4 25.9 7.2 65.1 20.1 22.3 26.2 24.5 36.0 34.3 45.0 14.1 4.2 19.9 14.2 55.2 44.2 52.8 6.8 16.3 15.7 26.4 56.6 48.0 13.3 25.7 15.8 34.1 61.1 16.5 12.0 41.4 33.8 17.0 12.8 24.2 46.1 11.9 24.7 49.8 17.4 23.0 21.3 84.8 21.3 30.0 118.8 63.4 18.5 42.2 5.8 37.6 35.2 26.0 23.4 10.2 23.0 26.5 28.3 47.2 12.9 34.1 1.0 29.7 26.7 19.5 25.0 0.0 51.8 0.6 24.5 0.2 0.2 33.1 54.5 27.2 49.5 34.4 28.8 0.0 0.3 31.9 30.8 0.0 0.2 0.3 63.0 1.0 19.9 0.6 31.6 4.2 18.1 2.8 27.1 70.3 24.2 2.6 40.8 78.8 30.3 17.3 22.0 70.7 50.1 0.5 30.7 0.4 21.7 7.3 24.0 0.0 55.2 0.0 0.3 0.0 0.4 1.1 0.1 3.7 0.2 0.2 0.7 1.6 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.4 33.5 53.1 73.9 39.8 34.3 45.0 55.2 44.2 56.6 33.8 46.1 84.8 16.6 12.8 12.2 90.1 13.2 10.6 12.5 8.0 12.0 28.8 9.3 8.8 17.0 5.7 10.1 1.8 27.1 2.0 1.4 0.3 0.0 4.9 4.9 8.3 48.3 24.2 4.2 0.0 86.9 0.5 2.7 17.9 3.1 10.0 0.0 15.8 14.6 0.1 4.4 35.3 90.9 0.2 4.1 9.1 14.3 3.5 11.5 9.2 8.8 53.4 5.2 22.1 0.0 130.2 178.2 6.0 1.4 18.0 8.6 33.5 0.0 1.6 8.8 9.7 13.1 15.5 24.2 5.5 17.2 8.9 9.2 3.4 4.3 5.0 0.3 11.9 SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ionocytes: 685.6;Muller glia cells: 544.7;Plasma cells: 1164.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 523.5;Karpas-707: 546.2;RPMI-8226: 1150.0;U-266/70: 587.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane" "Golgi apparatus" "HPA026816: AB_10602089, HPA047533: AB_2680078" "unprognostic (1.47e-2)" "unprognostic (2.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.44e-2)" "unprognostic (3.13e-3)" "unprognostic (4.48e-3)" "unprognostic (2.95e-1)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (4.33e-2)" "unprognostic (1.80e-2)" "unprognostic (1.72e-1)" "unprognostic (6.25e-2)" "unprognostic (3.83e-2)" "unprognostic (4.63e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" 24.6 76.7 110.0 86.5 117.5 63.1 81.8 122.9 140.5 57.8 94.4 92.3 126.7 40.1 284.6 42.5 41.4 47.3 30.0 112.9 146.4 70.2 219.0 62.7 104.2 137.3 130.2 29.9 374.0 153.9 155.2 28.4 136.8 225.7 78.2 108.1 397.3 62.3 15.7 29.7 97.8 30.1 123.7 81.4 138.5 28.1 113.5 53.0 163.7 20.0 117.8 59.4 21.2 135.8 82.4 100.0 52.9 74.1 31.9 6.8 64.7 72.4 62.9 89.9 55.2 78.3 42.5 176.8 109.9 46.6 67.6 82.8 84.7 59.0 58.4 523.5 113.8 58.5 69.3 242.3 99.3 199.4 87.6 20.4 140.7 56.2 161.1 20.2 33.7 78.4 67.4 546.2 34.6 100.0 79.0 79.2 48.1 140.4 60.5 72.8 50.0 1150.0 67.5 76.1 223.2 90.5 43.1 162.5 252.8 29.9 76.0 148.5 24.7 98.5 45.4 36.5 86.9 587.3 434.4 176.0 99.4 131.8 124.5 76.4 70.7 57.9 146.1 97.6 187.6 197.8 150.4 142.5 78.8 127.9 77.7 105.4 12.2 108.3 108.8 299.6 223.7 222.1 110.0 117.5 122.9 140.5 112.9 146.4 137.3 130.2 136.8 123.7 113.5 135.8 64.8 28.9 120.7 19.2 295.9 32.6 49.3 92.4 12.5 63.6 120.0 128.3 59.3 144.4 102.5 60.7 50.1 70.8 148.7 76.3 88.0 164.4 45.4 58.7 34.2 60.3 339.3 43.8 12.2 263.1 109.1 29.2 60.6 147.1 47.5 21.5 56.4 224.7 112.9 50.5 13.3 223.1 685.6 37.1 56.9 18.8 12.5 63.9 256.1 10.3 46.4 544.7 96.8 17.1 31.2 148.9 78.4 23.0 1164.8 380.9 99.3 118.8 81.3 89.3 6.6 23.1 70.6 110.2 81.5 35.5 45.5 149.7 92.3 40.1 88.3 79.2 GRP ENSG00000134443 "Gastrin releasing peptide" P07492 18 59220158-59230774 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1;stomach 1: 12.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 24.4;Early spermatids: 15.5;Ionocytes: 6.1;Late spermatids: 12.2;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.6" "Region enriched" "Detected in all" 4 "midbrain: 26.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BJ hTERT+: 5.1;fHDF/TERT166: 6.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 24.9" "Secreted in other tissues" NA NA 340000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.91e-2)" "unprognostic (1.85e-1)" "unprognostic (2.30e-3)" "unprognostic (3.21e-2)" "unprognostic (7.86e-3)" "unprognostic (3.01e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (1.79e-1)" "unprognostic (5.86e-4)" "unprognostic (2.65e-4)" "unprognostic (9.94e-2)" "unprognostic (6.99e-2)" "unprognostic (5.16e-2)" 0.3 0.2 3.2 0.2 2.6 0.0 2.6 1.3 5.0 0.1 2.8 2.1 0.1 0.3 0.3 0.0 0.0 0.3 0.0 6.1 6.0 0.4 0.0 9.0 0.0 3.0 26.1 0.0 1.2 7.0 3.9 0.0 2.4 2.7 0.1 0.5 0.0 0.1 0.0 0.4 0.7 1.2 2.6 0.3 12.3 2.4 3.5 0.1 6.1 0.0 0.0 0.1 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.0 0.0 0.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.6 1.3 5.0 6.1 6.0 3.0 26.1 2.4 2.6 3.5 1.6 0.1 0.0 0.0 0.0 0.0 0.4 0.1 3.2 0.0 0.0 0.4 24.4 0.1 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 2.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.3 12.2 0.3 0.1 0.0 4.7 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.1 0.1 6.6 0.0 0.2 1.2 0.9 0.0 0.0 0.0 0.3 0.0 0.0 4.2 RAX RX ENSG00000134438 "Retina and anterior neural fold homeobox" Q9Y2V3 18 59267035-59274086 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "pituitary gland: 6.6;retina: 16.0" "Cell type enriched" "Detected in some" 5 "Muller glia cells: 493.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "white matter: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 1.8;SH-SY5Y: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (4.14e-2)" "unprognostic (1.79e-1)" "unprognostic (3.76e-3)" "unprognostic (2.28e-1)" "unprognostic (2.22e-1)" "unprognostic (1.33e-1)" "unprognostic (3.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 6.6 0.0 0.0 0.1 0.0 16.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 83.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 493.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.7 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPLX4 CPX-IV ENSG00000166569 "Complexin 4" Q7Z7G2 18 59275156-59318649 "Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Sensory transduction, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 287 "retina: 314.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 74.1;Cone photoreceptor cells: 112.6;Muller glia cells: 31.8;Rod photoreceptor cells: 173.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA047627 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA047627: " "unprognostic (1.85e-1)" "unprognostic (4.46e-1)" "unprognostic (4.20e-2)" "unprognostic (4.05e-2)" "unprognostic (9.90e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 314.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.1 0.0 0.0 0.3 0.0 0.0 0.0 112.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 31.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 173.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 3.5;fallopian tube: 3.0;retina: 3.9" "Cell type enriched" "Detected in some" 7 "Bipolar cells: 7.3" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 70 "fHDF/TERT166: 94.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 10.2" HPA016719 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" 0.0 0.2 2.2 0.0 2.4 0.0 0.2 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.0 0.0 0.0 1.8 3.5 0.0 0.0 0.0 0.0 1.0 1.5 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.1 2.7 0.3 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 94.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.1 1.7 1.8 3.5 1.0 1.5 0.7 0.4 2.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDH20 "Cdh7, CDH7L3" ENSG00000101542 "Cadherin 20" Q9HBT6 18 61333430-61555779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 33.7;retina: 11.0;tongue: 24.1" "Group enriched" "Detected in some" 6 "Astrocytes: 1264.4;Oligodendrocyte precursor cells: 742.4;Oligodendrocytes: 1030.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.3" "Cell line enhanced" "Detected in some" "AF22: 1.8;ASC diff: 5.7;HHSteC: 2.6;SH-SY5Y: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015490 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA015490: AB_1845900" "unprognostic (2.15e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-2)" "unprognostic (3.68e-3)" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.87e-2)" "unprognostic (1.40e-2)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (3.82e-2)" "unprognostic (1.27e-1)" "unprognostic (3.01e-2)" "unprognostic (1.93e-1)" 4.7 0.1 22.1 0.0 29.9 0.0 0.9 24.8 19.9 0.2 2.3 0.0 0.0 0.1 0.6 0.8 0.2 0.0 0.1 20.0 19.8 0.1 0.0 0.0 0.0 27.5 28.7 0.0 0.1 0.0 1.6 0.0 29.1 0.2 0.0 11.0 0.4 0.0 4.7 0.5 0.2 0.0 21.5 0.1 0.1 0.4 23.1 0.0 0.3 24.1 0.0 0.3 0.0 33.7 0.0 0.0 1.8 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 22.1 29.9 24.8 19.9 20.0 19.8 27.5 28.7 29.1 21.5 23.1 33.7 0.2 0.0 0.0 1264.4 0.1 0.0 0.0 0.0 0.0 26.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 2.6 0.1 0.2 0.2 0.0 0.0 146.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 98.7 0.1 0.0 0.3 0.0 2.7 0.0 0.1 0.0 41.2 0.0 11.1 0.0 742.4 1030.7 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 1.1 0.0 1.0 0.2 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNF152 FLJ39176 ENSG00000176641 "Ring finger protein 152" Q8N8N0 18 61808067-61894247 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.3;choroid plexus: 62.3;kidney: 56.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 96.4;Proximal tubular cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 21.5;SH-SY5Y: 13.4;TIME: 14.2;U-138 MG: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.30e-2)" "unprognostic (1.97e-2)" "unprognostic (1.64e-1)" "unprognostic (8.55e-3)" "unprognostic (2.05e-1)" "unprognostic (2.09e-1)" "unprognostic (2.96e-3)" "unprognostic (3.62e-1)" "unprognostic (1.51e-2)" "unprognostic (8.13e-2)" "unprognostic (5.14e-2)" "unprognostic (6.73e-2)" "prognostic favorable (1.13e-8)" "prognostic unfavorable (2.85e-5)" "unprognostic (3.26e-2)" "unprognostic (2.82e-2)" "unprognostic (4.83e-2)" 7.4 3.4 5.4 0.9 13.9 0.9 6.7 48.3 5.3 8.2 62.3 7.2 1.7 6.3 3.6 4.5 5.2 3.8 7.6 6.1 10.6 56.5 22.1 7.0 0.5 25.5 13.7 4.0 2.5 2.4 2.9 6.5 28.7 5.3 6.6 5.0 14.0 2.8 2.3 11.4 5.5 4.1 8.5 0.6 6.3 1.3 21.1 0.6 5.4 2.3 0.8 4.2 7.5 14.9 0.0 0.0 4.8 1.0 4.4 0.6 0.0 3.1 9.4 0.7 0.5 0.0 0.1 0.1 0.9 4.9 0.1 21.5 5.9 11.4 1.3 0.0 0.6 0.0 0.0 0.0 2.3 0.0 0.1 0.7 8.1 3.6 2.4 2.1 8.7 0.1 0.0 0.1 1.4 0.9 0.8 0.0 0.3 0.7 0.0 0.3 3.1 0.0 0.5 3.7 3.9 13.4 0.0 8.7 1.5 4.2 5.1 0.0 14.2 21.6 2.2 0.0 0.5 0.1 0.0 0.0 0.7 0.0 7.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.4 13.9 48.3 5.3 6.1 10.6 25.5 13.7 28.7 8.5 21.1 14.9 26.8 0.0 0.0 9.4 0.2 42.3 28.1 11.1 11.4 19.1 16.2 10.3 4.8 12.8 10.5 20.2 0.0 0.4 0.9 58.1 46.9 2.5 0.4 16.8 18.5 17.1 16.2 8.0 9.9 2.7 0.1 9.5 18.3 29.9 0.0 0.1 10.8 96.4 0.1 21.9 20.0 5.6 32.6 1.8 7.7 1.4 8.7 2.2 28.4 2.8 0.0 3.5 0.0 16.6 27.5 1.7 34.9 18.4 0.3 8.7 46.6 159.0 1.8 3.6 65.7 2.8 59.7 0.2 0.5 28.0 32.5 0.3 1.7 18.7 16.2 21.2 PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 323.7;Alveolar cells type 2: 372.2;Club cells: 138.4;granulocytes: 159.0;Oligodendrocytes: 123.2;Respiratory ciliated cells: 145.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" 10.0 10.3 9.8 10.9 14.3 16.9 15.9 49.4 47.1 11.8 3.2 16.2 14.0 11.1 11.9 22.7 8.9 12.6 13.5 13.1 9.6 11.9 18.1 9.9 10.5 4.1 0.1 12.1 15.8 16.0 4.3 17.5 9.6 17.3 18.4 38.9 14.8 7.5 13.4 20.1 13.3 8.9 0.0 10.0 21.1 19.8 11.4 12.3 16.9 10.8 12.8 14.9 7.7 49.7 31.6 19.0 18.4 23.0 23.1 31.4 24.3 32.3 25.7 21.2 24.9 24.4 31.9 36.0 44.0 25.0 18.3 44.6 26.0 27.8 32.9 30.3 16.9 21.6 29.6 19.7 16.8 46.0 24.6 18.5 18.1 21.0 24.5 22.3 27.0 25.3 26.1 50.8 23.3 28.2 22.8 13.5 29.9 25.3 17.3 24.1 35.1 35.7 25.5 48.5 20.8 21.4 42.5 29.0 13.6 50.9 46.1 28.6 29.8 41.0 28.2 15.4 23.5 54.3 53.8 17.4 22.5 25.7 40.9 10.1 7.5 6.1 6.9 6.6 7.2 7.9 7.1 6.9 8.9 8.8 8.0 8.4 9.6 12.1 7.8 10.2 6.5 3.7 9.8 14.3 49.4 47.1 13.1 9.6 4.1 0.1 9.6 0.0 11.4 49.7 8.9 323.7 372.2 52.5 9.7 8.0 8.9 8.4 10.2 7.2 16.3 9.4 10.4 12.8 138.4 11.0 4.2 9.6 14.1 11.6 1.9 11.0 6.4 9.1 16.2 24.7 6.7 16.6 54.5 9.5 11.5 26.6 10.2 11.5 159.0 19.3 10.0 12.0 10.1 6.7 41.3 11.6 10.2 9.2 4.0 6.5 7.2 26.9 3.6 44.0 7.9 7.3 3.1 57.8 123.2 10.9 9.4 3.8 8.2 11.7 5.6 5.0 145.5 6.6 6.6 6.8 6.7 20.7 7.3 17.4 17.0 10.4 18.5 10.5 12.3 12.1 RELCH "FLJ33841, HsT3308, HsT885, KIAA1468" ENSG00000134444 "RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing" Q9P260 18 62187255-62310249 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 7.0;Cardiomyocytes: 9.4;Cytotrophoblasts: 6.5;dendritic cells: 8.2;Extravillous trophoblasts: 4.4;Hofbauer cells: 7.2;Plasma cells: 5.2;Syncytiotrophoblasts: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039708, HPA040038" Approved Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Centriolar satellite, Cytosol" "HPA039708: AB_10794753, HPA040038: AB_10793860" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.98e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (4.03e-2)" "unprognostic (1.98e-3)" "unprognostic (2.44e-2)" "unprognostic (6.30e-2)" "unprognostic (3.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.36e-1)" "unprognostic (4.84e-3)" "unprognostic (2.47e-2)" "unprognostic (6.86e-2)" "unprognostic (3.54e-1)" "unprognostic (1.71e-2)" 8.3 8.8 8.7 9.6 10.8 14.2 11.9 11.1 10.0 11.8 7.2 11.5 9.5 8.5 11.8 25.4 7.7 7.9 7.5 9.7 9.3 9.6 7.9 8.0 11.8 7.9 7.6 8.2 8.3 10.3 11.0 8.1 8.2 12.1 14.4 16.3 12.5 8.8 6.8 20.6 10.8 6.2 7.6 11.2 12.7 5.3 8.8 10.8 9.5 5.9 13.2 10.0 16.2 9.4 9.7 8.7 10.4 10.0 10.8 12.7 11.1 17.0 14.1 15.0 16.5 4.5 8.8 6.6 8.6 15.1 9.8 19.7 14.9 10.2 18.3 6.0 9.3 5.6 9.7 10.4 9.6 10.8 7.4 9.4 12.3 12.8 7.8 12.3 10.3 6.2 4.2 6.5 15.9 5.7 6.7 9.3 6.0 6.5 7.3 8.2 13.0 7.9 17.1 19.1 14.7 7.8 10.2 14.9 8.9 13.4 7.7 11.6 12.9 15.9 5.0 6.9 8.6 19.0 3.7 6.4 11.2 11.4 13.0 1.4 1.0 1.2 1.1 0.8 0.8 0.8 1.0 1.0 1.0 0.9 1.1 1.3 1.7 1.1 0.7 0.7 1.3 0.6 8.7 10.8 11.1 10.0 9.7 9.3 7.9 7.6 8.2 7.6 8.8 9.4 7.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 6.5 8.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 4.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 6.6 1.1 0.0 0.0 0.0 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 ZCCHC2 "C18orf49, FLJ20222, FLJ20281, KIAA1744" ENSG00000141664 "Zinc finger CCHC-type containing 2" Q9C0B9 18 62523025-62587709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 143.8;Late spermatids: 158.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040943 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Cytosol" Nucleoplasm "HPA040943: AB_10795496" "unprognostic (9.32e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (4.07e-2)" "unprognostic (4.79e-2)" "unprognostic (2.60e-1)" "unprognostic (1.93e-1)" "unprognostic (8.25e-2)" "unprognostic (2.32e-2)" "unprognostic (1.30e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-1)" "unprognostic (3.72e-2)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 10.7 5.5 6.2 5.8 6.6 26.5 9.1 9.3 8.2 6.7 6.0 7.1 6.7 6.3 5.9 5.5 7.8 8.6 8.5 5.5 6.9 5.5 23.3 10.2 7.0 7.2 6.8 8.0 6.2 5.8 8.0 8.1 6.7 7.3 5.4 10.0 37.2 5.3 12.2 11.6 7.5 5.8 5.3 9.0 6.4 12.0 6.6 7.6 7.3 7.3 6.3 7.9 6.5 11.5 8.0 6.8 5.8 11.5 17.1 7.3 10.9 4.5 6.7 10.5 10.4 3.7 4.8 22.4 5.8 7.4 8.6 13.2 18.6 9.9 4.3 15.5 8.8 5.9 15.6 25.2 5.9 11.4 8.3 7.2 12.6 6.7 12.3 7.6 19.9 9.9 6.4 7.3 3.5 6.5 7.5 4.8 3.7 5.8 6.7 9.7 6.1 0.1 7.3 8.0 7.2 4.5 7.5 16.8 6.6 10.2 5.9 8.9 8.6 10.3 7.0 4.1 6.5 2.8 5.8 9.4 7.6 4.7 3.9 0.0 0.3 0.8 0.5 0.5 0.4 0.1 0.3 0.4 0.1 0.4 0.6 0.4 1.5 0.2 0.1 0.3 0.4 0.1 6.2 6.6 9.3 8.2 5.5 6.9 7.2 6.8 6.7 5.3 6.6 11.5 23.1 25.6 18.8 28.1 10.8 26.6 16.9 7.5 10.8 33.1 15.2 13.2 18.8 20.0 12.4 16.5 54.2 7.4 33.6 10.2 3.9 6.8 143.8 24.1 12.3 28.8 12.6 8.2 48.5 6.2 10.9 9.7 10.2 27.5 2.5 4.4 17.5 35.4 14.1 43.7 33.9 15.5 2.0 44.4 22.0 158.6 8.1 30.6 7.2 29.0 11.9 7.7 9.2 37.2 51.7 5.1 9.1 7.9 10.7 16.5 8.4 5.3 10.8 19.5 6.6 15.6 15.0 16.3 15.2 15.3 18.5 6.8 22.6 5.6 11.5 12.2 PHLPP1 "KIAA0606, PHLPP, PLEKHE1, PPM3A, SCOP" ENSG00000081913 "PH domain and leucine rich repeat protein phosphatase 1" O60346 18 62715541-62980433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 107.2" "Group enriched" "Detected in many" 10 "Astrocytes: 423.7;Oligodendrocyte precursor cells: 538.3;Oligodendrocytes: 1663.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "neutrophil: 4.0;T-reg: 1.3" "Group enriched" "Detected in many" 7 "granulocytes: 4.0;T-cells: 1.3" "Cell line enhanced" "Detected in all" "REH: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020200 Approved "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA020200: AB_2670383" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" "unprognostic (2.26e-1)" "unprognostic (1.18e-1)" "unprognostic (1.89e-1)" "unprognostic (3.07e-2)" "unprognostic (5.57e-2)" "unprognostic (5.24e-1)" "unprognostic (1.63e-1)" "unprognostic (3.10e-1)" "unprognostic (2.95e-1)" "unprognostic (6.03e-2)" "prognostic favorable (5.35e-8)" "unprognostic (1.52e-1)" "unprognostic (3.49e-2)" "unprognostic (8.13e-2)" "unprognostic (8.25e-2)" 5.5 14.6 46.4 1.9 74.3 7.3 6.4 49.5 59.8 4.4 17.1 5.2 5.4 4.6 1.9 7.6 3.4 4.1 3.4 45.6 46.4 3.2 16.6 3.4 2.7 61.8 58.4 4.4 7.0 5.7 7.5 5.5 53.8 4.0 5.6 16.1 10.8 3.5 4.2 12.5 4.9 3.3 47.0 1.8 4.9 10.8 58.7 4.4 4.6 3.7 3.6 5.5 4.8 107.2 13.7 5.0 20.2 6.8 3.4 2.9 15.8 4.0 3.6 7.8 8.0 11.1 8.0 9.1 2.4 6.1 3.1 16.3 10.5 6.4 10.0 28.4 8.8 3.1 5.4 20.6 4.8 4.7 1.5 3.0 4.1 8.4 7.6 6.4 5.6 4.9 8.0 17.9 7.6 3.0 3.5 4.1 8.2 2.7 4.9 32.7 11.5 11.1 4.5 17.5 9.3 3.7 4.4 9.9 8.2 11.8 4.4 13.3 7.2 6.4 3.0 3.9 9.4 2.0 1.1 10.6 3.8 5.4 5.0 0.0 0.1 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 4.0 0.3 0.1 0.2 1.3 0.1 46.4 74.3 49.5 59.8 45.6 46.4 61.8 58.4 53.8 47.0 58.7 107.2 10.1 3.2 1.5 423.7 1.9 16.8 5.0 2.9 8.0 21.2 12.1 11.3 4.1 11.5 6.3 0.0 29.2 12.9 3.3 8.4 1.9 3.8 33.5 13.7 6.0 8.1 12.1 3.8 80.1 4.1 5.8 7.0 10.2 26.6 2.5 9.6 5.3 21.5 2.4 26.9 64.7 8.5 2.0 2.5 9.8 36.4 5.9 5.8 24.9 79.6 2.6 83.6 2.1 538.3 1663.2 4.5 8.0 3.8 1.0 7.5 7.4 1.9 10.0 17.4 0.0 13.5 5.3 8.0 15.4 13.2 18.6 26.1 2.7 8.3 11.1 11.0 BCL2 "Bcl-2, PPP1R50" ENSG00000171791 "BCL2 apoptosis regulator" P10415 18 63123346-63320128 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Apoptosis "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 271.6;Inhibitory neurons: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 18 "B-cells: 5.4;T-cells: 8.5" "Cell line enhanced" "Detected in many" "HDLM-2: 44.2;HL-60: 43.7;Karpas-707: 72.9;U-266/70: 217.4" "Low region specificity" "Detected in all" "CAB000003, HPA055295" Enhanced Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear membrane" Nucleoplasm "CAB000003: AB_2064429, HPA055295: AB_2682776" "unprognostic (1.11e-3)" "prognostic favorable (5.13e-5)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.93e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (8.51e-2)" "prognostic favorable (1.29e-8)" "unprognostic (6.67e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (2.63e-1)" 12.8 1.9 5.5 10.2 7.8 5.0 9.6 4.7 3.4 10.7 0.0 6.2 4.4 11.6 2.9 5.9 11.8 6.5 5.3 2.9 6.6 6.7 2.1 3.7 14.7 11.2 7.9 14.5 3.1 13.0 4.7 4.6 7.5 6.4 5.5 2.1 3.7 7.0 16.5 4.8 8.1 6.6 7.9 17.9 3.8 1.5 8.2 18.3 24.0 8.8 14.6 5.4 7.7 5.7 1.7 0.3 6.8 5.9 6.7 1.3 2.4 1.0 0.7 2.4 2.0 3.5 0.4 0.3 1.1 0.9 4.7 0.4 6.7 0.9 1.5 44.2 1.6 0.5 2.0 0.7 2.0 43.7 5.6 1.7 0.8 3.3 5.8 1.1 0.7 4.3 0.8 72.9 2.2 1.4 9.8 10.7 1.5 0.8 1.3 39.5 1.9 26.5 7.4 8.5 7.2 6.4 0.3 0.3 8.5 1.4 0.3 29.9 0.3 9.9 3.3 0.9 5.1 217.4 40.1 2.9 1.9 24.9 6.0 0.3 0.0 0.0 1.9 0.0 7.6 5.4 6.3 3.4 0.1 3.1 3.3 3.2 0.0 0.2 0.3 0.2 8.5 1.3 5.5 7.8 4.7 3.4 2.9 6.6 11.2 7.9 7.5 7.9 8.2 5.7 7.1 0.0 1.1 271.6 84.9 19.5 33.6 1.6 13.6 1.9 39.7 19.7 17.4 18.6 2.4 7.3 0.0 14.0 39.9 2.7 15.6 3.7 0.4 9.8 9.8 5.9 5.4 3.8 60.7 0.0 0.7 15.8 5.6 24.9 15.8 38.8 3.9 1.2 9.4 0.0 102.3 10.5 24.4 15.0 29.6 1.9 8.7 29.0 46.2 88.1 19.7 18.8 18.6 76.4 56.7 0.2 5.9 13.9 50.1 41.6 0.9 18.0 0.1 0.6 26.3 48.8 19.7 0.3 1.3 6.2 17.6 49.1 76.1 24.1 9.8 76.2 KDSR "DHSR, FVT1, SDR35C1" ENSG00000119537 "3-ketodihydrosphingosine reductase" Q06136 18 63327726-63367228 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Palmoplantar keratoderma, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003673, HPA044884" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "CAB003673: AB_425440, HPA044884: AB_2679131" "unprognostic (4.44e-2)" "unprognostic (8.57e-2)" "unprognostic (2.52e-2)" "unprognostic (4.56e-2)" "unprognostic (5.88e-3)" "unprognostic (7.50e-3)" "unprognostic (1.80e-2)" "unprognostic (2.66e-1)" "unprognostic (2.97e-1)" "unprognostic (1.97e-1)" "unprognostic (2.70e-2)" "unprognostic (6.81e-2)" "prognostic favorable (9.53e-6)" "unprognostic (3.32e-2)" "unprognostic (5.77e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-3)" 32.3 22.4 12.8 8.1 19.9 4.8 25.4 19.5 16.7 26.9 12.3 24.6 7.0 22.7 20.8 22.4 18.9 12.6 20.7 12.7 16.4 20.1 36.7 21.5 7.0 20.6 17.7 21.3 15.7 13.1 12.1 8.5 20.0 16.3 7.4 7.0 22.8 11.6 16.7 44.5 15.1 13.3 17.6 8.4 16.4 6.1 16.6 7.1 17.2 8.9 6.8 23.9 23.4 22.4 14.9 6.5 6.7 7.5 52.6 39.0 13.0 48.8 29.7 10.5 13.9 2.7 10.0 15.1 20.3 19.1 17.4 64.6 8.7 27.3 12.8 28.6 14.5 11.6 8.7 3.4 40.1 22.0 7.8 37.4 50.7 16.8 47.9 19.3 10.5 9.9 9.5 21.0 28.1 6.2 23.6 9.7 8.0 3.7 23.5 15.5 19.7 21.9 29.0 9.6 8.5 16.4 23.4 11.3 21.9 8.8 6.1 12.1 24.9 44.0 10.6 14.8 21.3 90.4 44.9 8.7 33.2 13.0 13.4 0.1 5.2 0.5 6.5 8.1 26.6 5.7 13.6 10.2 8.0 4.7 9.3 6.1 1.3 14.2 3.9 3.8 19.1 5.3 12.8 19.9 19.5 16.7 12.7 16.4 20.6 17.7 20.0 17.6 16.6 22.4 53.1 35.3 49.1 21.9 30.1 158.6 131.7 47.0 122.3 37.4 63.4 63.6 27.7 62.9 43.5 38.6 27.1 58.8 15.6 34.6 15.6 50.7 1.0 43.9 53.0 48.1 20.4 17.4 19.1 36.7 70.4 82.0 26.5 64.9 26.0 52.3 51.8 88.3 36.4 40.4 24.2 31.8 42.7 32.2 47.7 6.5 71.1 39.9 56.9 14.0 31.5 56.5 13.4 21.6 57.0 47.4 44.6 70.7 24.5 104.3 43.4 39.6 41.2 41.1 32.9 73.7 48.4 1.3 5.2 89.7 143.1 91.4 37.7 51.1 40.3 94.7 VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved "Vesicles,Intermediate filaments" No No 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Vesicles "Intermediate filaments" "CAB046445: AB_10603252, HPA040393: , HPA057649: AB_2683489" "unprognostic (8.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.10e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.23e-4)" "unprognostic (4.59e-1)" "unprognostic (1.40e-1)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" 24.2 18.3 10.5 25.5 13.1 52.6 28.8 13.2 17.8 26.8 9.3 42.3 35.1 22.7 19.5 75.4 18.6 23.7 16.2 10.3 14.6 23.8 28.4 23.8 31.2 13.5 15.9 19.3 17.3 27.8 11.5 28.7 14.0 23.4 37.0 7.0 24.7 19.5 11.0 32.3 36.4 21.0 12.6 28.8 32.5 12.1 12.5 31.4 28.5 13.0 39.1 30.2 31.1 15.6 57.1 21.9 22.4 24.5 33.5 47.1 38.9 48.6 45.5 36.4 39.2 15.7 39.4 54.1 31.2 35.7 30.9 119.6 26.8 53.1 47.5 40.6 22.3 27.6 27.8 23.7 48.6 94.5 56.8 43.1 80.3 32.3 56.2 36.5 33.9 31.0 14.3 49.4 52.1 20.2 59.9 29.2 23.2 22.7 32.3 48.8 47.2 52.4 45.6 66.2 38.2 33.6 36.9 35.4 55.3 28.3 34.2 50.5 52.8 55.4 27.3 21.6 32.7 163.6 86.5 69.3 31.9 44.0 42.3 163.6 54.6 125.0 52.2 56.5 49.0 64.8 54.3 54.2 46.2 73.4 48.2 51.1 185.9 68.4 76.5 45.6 66.7 56.6 10.5 13.1 13.2 17.8 10.3 14.6 13.5 15.9 14.0 12.6 12.5 15.6 52.0 115.4 57.4 21.5 62.4 68.8 47.2 66.5 44.9 37.0 54.4 46.0 39.5 47.1 72.4 33.1 22.9 70.0 92.2 142.0 45.0 48.0 113.3 92.2 74.0 44.6 45.5 27.8 27.3 42.1 56.7 51.0 47.4 145.5 59.3 37.7 36.8 55.8 46.4 43.7 29.6 76.8 67.1 58.8 33.0 15.5 49.0 58.0 32.0 18.7 53.4 39.2 76.2 18.6 49.5 91.3 120.7 36.5 42.1 43.1 61.8 57.9 85.1 31.5 59.2 45.6 54.7 30.1 29.4 87.5 83.4 140.4 67.4 56.5 72.6 79.5 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPINB12 YUKOPIN ENSG00000166634 "Serpin family B member 12" Q96P63 18 63542369-63569329 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 13.9;skin 1: 59.1;vagina: 25.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "cervical cancer: 7.3;head and neck cancer: 2.1;lung cancer: 1.9;melanoma: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 8200000 "Cluster 31: Skin - Epidermis development" "unprognostic (7.35e-2)" "prognostic favorable (1.76e-4)" "unprognostic (1.57e-1)" "unprognostic (2.00e-1)" "unprognostic (8.10e-2)" 0.0 0.0 0.1 0.0 0.2 0.1 3.3 0.4 0.2 13.9 0.2 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 59.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 3.4 0.0 0.1 2.1 0.0 25.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 SERPINB13 "headpin, HUR7, hurpin, PI13" ENSG00000197641 "Serpin family B member 13" Q9UIV8 18 63586989-63604639 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 56.6;esophagus: 180.4;vagina: 135.0" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 58.8;Club cells: 54.8;Squamous epithelial cells: 148.6" "Group enriched" "Detected in many" 5 "cervical cancer: 45.9;head and neck cancer: 27.6;lung cancer: 12.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 129 "HaCaT: 198.9;hTCEpi: 74.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052630, HPA057129" Enhanced Approved "Nuclear speckles,Cytosol" NA NA 210000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles, Cytosol" "HPA052630: AB_2681891, HPA057129: AB_2683347" "unprognostic (3.49e-2)" "unprognostic (3.73e-1)" "unprognostic (1.11e-1)" "unprognostic (7.27e-2)" "unprognostic (2.28e-1)" "unprognostic (4.29e-2)" "unprognostic (2.81e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.1 56.6 0.0 0.0 0.0 0.0 0.0 180.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 35.7 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.2 0.0 0.0 22.9 3.3 135.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 1.7 1.9 58.8 13.1 0.0 0.0 0.1 0.1 0.0 54.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 8.5 0.0 0.0 0.0 1.0 0.0 0.0 148.6 1.3 0.5 0.0 0.0 0.0 19.9 SERPINB4 "LEUPIN, PI11, SCCA-2, SCCA1, SCCA2" ENSG00000206073 "Serpin family B member 4" P48594 18 63637259-63644256 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 78.6;esophagus: 93.3;vagina: 150.9" "Cell type enriched" "Detected in some" 4 "Basal respiratory cells: 3577.0" "Group enriched" "Detected in many" 5 "cervical cancer: 104.1;head and neck cancer: 29.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 2.2;HSkMC: 1.1;SiHa: 1.7;U-2197: 6.1" "HPA048341, HPA049988, HPA055992" Supported NA NA 10000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (8.81e-3)" "unprognostic (9.43e-2)" "unprognostic (8.96e-3)" "unprognostic (4.38e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (2.46e-1)" "unprognostic (4.37e-2)" "unprognostic (1.27e-2)" 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 78.6 0.0 0.0 0.0 0.6 0.0 93.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 0.0 23.3 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.0 0.0 4.5 21.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 3577.0 0.0 0.0 0.0 0.0 0.0 0.0 825.8 0.0 0.0 0.0 0.0 0.0 0.0 23.9 1.4 0.1 0.1 0.2 0.0 0.0 0.0 21.7 0.2 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 97.6 0.0 0.0 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.3 0.0 0.0 0.0 32.4 0.0 0.3 53.0 0.0 0.0 0.0 10.7 0.1 0.0 14.8 0.0 0.8 0.0 0.0 0.0 60.5 SERPINB11 EPIPIN ENSG00000206072 "Serpin family B member 11" Q96P15 18 63647579-63726432 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 27.4;prostate: 32.5" "Cell type enhanced" "Detected in some" "Club cells: 6.8;Prostatic glandular cells: 3.3;Respiratory ciliated cells: 4.4;Squamous epithelial cells: 13.7;Urothelial cells: 21.9" "Cancer enriched" "Detected in some" 5 "prostate cancer: 6.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (5.04e-3)" "unprognostic (4.76e-2)" "unprognostic (4.05e-2)" "unprognostic (3.44e-1)" "unprognostic (2.62e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 32.5 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 9.0 2.9 6.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.2 0.0 0.0 21.9 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SERPINB7 MEGSIN ENSG00000166396 "Serpin family B member 7" O75635 18 63752935-63805376 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lymphoid tissue: 38.4;skin 1: 129.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 79.5;Basal respiratory cells: 353.3;Club cells: 120.7;Ductal cells: 157.8;Extravillous trophoblasts: 82.2;Pancreatic endocrine cells: 276.5" "Cancer enhanced" "Detected in many" "cervical cancer: 8.0;head and neck cancer: 8.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 240.4;fHDF/TERT166: 170.8;HaCaT: 412.8;HBEC3-KT: 131.9;HBF TERT88: 223.0;hTERT-HME1: 130.9;U-138 MG: 219.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "cerebral cortex: 12.9;hippocampal formation: 11.4" HPA024200 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 160000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Endoplasmic reticulum" Mitochondria "HPA024200: AB_1856730" "unprognostic (8.66e-3)" "unprognostic (6.31e-3)" "unprognostic (6.55e-2)" "unprognostic (4.03e-4)" "unprognostic (9.11e-2)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (9.99e-2)" "unprognostic (4.70e-2)" "prognostic unfavorable (3.03e-5)" "unprognostic (2.02e-1)" "unprognostic (6.81e-2)" "unprognostic (1.62e-1)" "unprognostic (3.37e-2)" "unprognostic (2.02e-1)" "unprognostic (1.76e-3)" 0.5 0.0 0.0 0.4 0.0 0.0 13.0 0.0 0.0 3.0 0.0 0.7 0.0 0.7 0.0 1.8 0.0 0.3 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.7 0.0 0.5 129.5 0.0 0.1 0.0 0.0 0.7 0.4 0.1 4.5 0.0 0.0 38.4 0.0 4.8 0.0 28.2 0.1 0.0 0.1 0.0 3.7 0.0 240.4 48.2 36.0 26.6 0.0 1.0 0.1 0.1 170.8 62.5 412.8 0.1 131.9 223.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 8.6 22.9 5.5 130.9 1.8 0.0 0.0 0.0 0.8 21.7 0.0 0.0 0.0 0.6 0.0 11.9 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.8 0.1 0.2 0.0 219.4 8.1 4.7 22.8 0.1 0.0 0.0 22.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 79.5 0.9 353.3 0.0 0.0 0.1 0.0 0.0 0.0 120.7 0.0 0.0 1.9 0.0 0.5 0.0 157.8 0.1 0.0 0.0 0.5 0.0 0.0 0.2 8.8 82.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.0 2.0 0.0 3.0 0.0 0.0 0.2 3.6 0.0 1.6 0.0 0.0 0.5 0.3 276.5 1.1 0.0 0.0 4.5 0.0 0.3 13.0 0.0 0.0 0.0 5.4 0.0 0.2 0.0 21.9 6.2 0.1 0.0 0.0 8.2 SERPINB2 "HsT1201, PAI2, PLANH2" ENSG00000197632 "Serpin family B member 2" P05120 18 63871692-63903888 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Plasminogen activation" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 239.1;lymphoid tissue: 81.2;skin 1: 89.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2243.9;Suprabasal keratinocytes: 1053.6;Syncytiotrophoblasts: 439.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 26.5" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.3;thalamus: 1.1" "Immune cell enhanced" "Detected in some" "basophil: 22.0;eosinophil: 10.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 22.0" "Cell line enhanced" "Detected in many" "GAMG: 282.7;HaCaT: 699.1;U-138 MG: 807.0;U-2197: 1243.9" "Region enriched" "Detected in single" 15 "cerebellum: 2.6" "Not detected" "Not detected" "HPA015480, HPA076596, HPA076608" Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 28: Keratinocytes - Keratinization" "HPA015480: AB_1855456, HPA076596: , HPA076608: " "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.46e-2)" "unprognostic (1.36e-4)" "unprognostic (1.17e-1)" "unprognostic (1.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (3.76e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-6)" "unprognostic (3.89e-2)" "unprognostic (3.94e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.55e-5)" 21.0 0.3 0.0 8.6 0.0 36.5 8.7 0.0 1.3 21.0 0.0 0.5 0.1 0.7 0.0 239.1 8.4 0.7 1.0 0.0 0.2 0.2 0.3 2.8 0.0 0.0 0.1 0.3 1.1 0.2 0.1 50.1 0.0 0.2 0.0 0.0 31.2 0.0 0.3 89.2 0.1 1.7 0.0 0.3 0.8 0.0 1.1 2.6 0.1 0.2 81.2 6.6 45.4 0.0 1.4 0.0 0.0 0.8 1.3 0.6 0.2 169.2 179.2 6.0 13.1 0.9 0.4 0.2 0.0 6.1 282.7 699.1 0.0 143.7 118.6 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.5 1.5 13.9 81.7 37.0 1.8 0.6 0.0 0.6 0.4 2.8 0.0 0.2 0.4 0.3 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 1.1 0.0 0.6 0.7 15.7 13.9 807.0 0.4 1243.9 0.0 0.2 0.1 0.0 21.6 1.8 96.7 22.0 4.9 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.5 0.0 0.2 2243.9 4.1 82.1 0.0 0.0 0.6 0.1 0.7 0.0 153.4 0.0 0.0 6.2 0.1 0.0 0.0 92.6 0.0 0.1 0.1 5.5 0.0 0.0 0.0 7.1 1.7 11.0 0.0 0.3 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 26.4 2.9 86.4 0.0 0.0 73.1 94.3 0.0 3.9 0.0 0.0 0.0 0.0 167.2 0.0 0.0 1.0 18.9 0.0 0.0 94.5 0.0 0.0 0.3 14.8 0.0 0.0 94.7 1053.6 439.3 2.5 0.0 0.0 52.0 SERPINB10 "bomapin, PI10" ENSG00000242550 "Serpin family B member 10" P48595 18 63897174-63936111 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 60 "bone marrow: 74.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.4;Club cells: 2.7;Erythroid cells: 1.3;Kupffer cells: 1.2;monocytes: 4.7;Respiratory ciliated cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.3;eosinophil: 1.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "U-937: 104.1" "Not detected" "Not detected" "HPA015480, HPA059582" Uncertain Supported Nucleoplasm,Cytosol NA NA 59000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA015480: AB_1855456, HPA059582: AB_2684072" "unprognostic (4.66e-1)" "unprognostic (5.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.19e-1)" "unprognostic (9.56e-2)" "unprognostic (2.56e-1)" "unprognostic (4.59e-1)" "unprognostic (1.10e-1)" "unprognostic (3.64e-1)" "unprognostic (1.25e-4)" 0.3 0.1 0.1 0.1 0.2 74.7 0.0 0.5 0.4 0.3 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.2 0.0 0.1 1.2 0.1 0.1 0.1 0.7 0.1 0.0 0.3 0.9 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 14.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.7 0.1 1.5 0.1 0.0 0.0 0.1 0.1 104.1 0.1 0.1 1.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.3 0.1 0.2 0.5 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.7 0.0 0.0 4.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.2 HMSD "ACC-6, ACC6, C18orf53" ENSG00000221887 "Histocompatibility minor serpin domain containing" "A8MTL9, P0C7T4" 18 63949301-63981774 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.8" "Group enriched" "Detected in some" 4 "monocytes: 28.4;Oligodendrocytes: 11.1;Spermatogonia: 9.6" "Cancer enhanced" "Detected in single" "cervical cancer: 1.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;GAMG: 8.6;HDLM-2: 18.8;Karpas-707: 7.1" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "unprognostic (5.83e-3)" "unprognostic (1.40e-1)" "unprognostic (1.40e-2)" "unprognostic (5.42e-3)" "unprognostic (6.20e-2)" "unprognostic (1.16e-2)" "unprognostic (4.91e-2)" "unprognostic (3.80e-1)" "unprognostic (1.41e-2)" "unprognostic (5.19e-3)" "unprognostic (8.67e-2)" "unprognostic (1.44e-1)" "unprognostic (7.14e-6)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.45e-3)" "unprognostic (3.55e-1)" 1.3 0.4 2.3 0.8 3.3 0.0 0.3 3.8 6.1 0.2 1.3 0.4 0.1 0.0 0.0 0.9 0.7 0.0 0.9 2.2 2.7 0.5 0.7 1.8 1.6 5.7 3.8 0.2 0.2 0.0 0.1 0.0 5.1 0.2 0.4 0.1 0.2 0.0 0.1 0.7 0.9 0.0 3.6 1.1 0.3 0.6 3.5 0.9 0.7 0.1 1.2 0.1 0.5 6.8 3.3 0.0 0.0 0.0 3.2 7.4 0.0 0.6 2.1 0.3 3.9 0.0 0.8 0.0 0.0 0.9 8.6 3.4 1.3 0.2 2.5 18.8 0.0 0.0 0.1 0.0 0.8 0.0 0.0 4.1 0.0 2.7 0.1 1.0 0.0 0.0 0.0 7.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.0 0.0 0.2 0.0 0.3 1.3 0.0 0.0 3.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.3 3.3 3.8 6.1 2.2 2.7 5.7 3.8 5.1 3.6 3.5 6.8 0.1 3.2 0.0 0.3 0.0 1.7 0.2 3.6 0.0 0.1 0.1 0.1 0.3 0.0 0.9 0.0 0.0 0.4 2.9 0.0 0.0 0.5 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.5 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 2.0 0.0 2.7 0.4 0.3 0.5 0.0 0.0 28.4 0.9 0.0 0.5 11.1 0.4 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.4 1.5 9.6 0.9 0.1 0.1 0.2 0.1 0.6 0.1 SERPINB8 "CAP2, PI8" ENSG00000166401 "Serpin family B member 8" P50452 18 63970029-64019779 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 58.8" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 120.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB034300 Enhanced Approved Nucleoplasm,Cytosol NA NA 920000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB034300: AB_2186486" "unprognostic (8.49e-2)" "unprognostic (4.87e-2)" "unprognostic (4.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (7.71e-2)" "unprognostic (4.50e-2)" "unprognostic (2.19e-1)" "unprognostic (2.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.58e-3)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (8.73e-2)" "unprognostic (3.48e-2)" "unprognostic (1.25e-1)" "unprognostic (1.90e-1)" 10.8 9.5 2.6 15.8 3.2 30.3 9.5 3.4 3.6 9.3 3.5 8.6 6.3 4.7 1.5 30.1 4.4 18.1 5.7 2.8 3.9 9.0 37.8 12.1 13.4 5.2 4.0 4.2 7.1 2.7 3.7 7.2 4.8 4.6 9.7 2.3 10.8 3.3 3.0 58.8 8.8 7.3 4.3 7.8 7.1 2.7 4.6 6.5 5.3 2.3 18.3 23.7 17.1 4.5 24.2 4.8 4.0 28.8 13.9 19.7 2.0 75.6 72.9 46.8 46.4 1.0 10.8 0.4 27.2 45.6 23.3 38.3 0.8 48.2 66.3 33.4 0.9 0.0 8.7 2.5 32.1 120.0 10.0 19.1 41.3 63.6 20.9 30.3 51.4 5.1 0.7 13.4 32.9 2.1 2.1 13.5 1.7 3.8 23.6 1.7 10.5 2.1 21.4 27.1 2.3 2.4 15.0 2.3 28.8 3.3 0.8 45.4 79.2 71.0 15.4 8.8 31.1 5.9 1.0 0.1 72.5 69.2 63.0 2.7 44.2 2.0 7.6 34.2 6.8 7.1 6.3 4.7 53.8 9.9 3.3 5.2 12.4 4.6 18.1 28.8 8.9 11.2 2.6 3.2 3.4 3.6 2.8 3.9 5.2 4.0 4.8 4.3 4.6 4.5 6.0 3.2 8.3 0.3 9.1 41.0 25.9 38.9 5.7 0.4 5.5 3.8 1.2 8.6 25.5 0.0 0.0 4.9 13.4 12.3 0.0 30.0 1.3 7.6 3.3 8.7 1.8 3.0 1.8 19.2 5.6 8.6 8.2 16.3 4.5 0.9 7.5 9.6 15.3 0.0 1.3 3.5 12.2 24.8 35.1 1.1 0.9 35.9 16.0 1.0 29.0 1.6 5.2 1.5 2.9 42.2 10.7 0.0 3.5 13.0 8.5 2.9 12.9 0.3 0.0 12.3 9.8 1.7 2.3 18.2 48.4 31.3 8.2 1.4 5.0 33.3 CDH7 ENSG00000081138 "Cadherin 7" Q9ULB5 18 65750252-65890337 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 16.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 45.7;Inhibitory neurons: 111.4;Muller glia cells: 39.3" "Cancer enhanced" "Detected in single" "prostate cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.2;HEK 293: 2.9;Karpas-707: 5.6;RH-30: 7.3;U-87 MG: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061419 Supported NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA061419: AB_2684511" "unprognostic (2.81e-3)" "unprognostic (6.95e-2)" "unprognostic (2.26e-1)" "unprognostic (2.24e-2)" "unprognostic (3.45e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-3)" "unprognostic (2.88e-1)" "unprognostic (4.28e-4)" "unprognostic (2.70e-2)" "unprognostic (1.49e-1)" "unprognostic (1.72e-1)" 0.0 0.1 0.6 0.0 4.1 0.0 0.0 11.6 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 0.0 0.0 0.0 15.9 3.2 0.3 0.0 0.0 0.4 0.0 16.4 0.7 0.0 3.6 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.4 7.3 0.4 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 7.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.7 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 4.1 11.6 3.5 0.4 3.0 15.9 3.2 16.4 0.6 7.3 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.4 0.0 0.0 14.9 0.1 0.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.6 3.5 0.0 45.7 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 111.4 0.0 0.0 0.0 0.0 3.2 0.6 0.1 0.0 1.0 0.0 39.3 0.0 11.1 1.4 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 4.1 6.6 0.1 0.2 1.4 4.4 0.0 0.0 0.0 0.1 1.1 0.0 0.2 CDH19 CDH7 ENSG00000071991 "Cadherin 19" Q9H159 18 66501083-66604138 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.4;heart muscle: 37.1;intestine: 19.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 60.1;Melanocytes: 44.4;Oligodendrocyte precursor cells: 57.8;Oligodendrocytes: 192.6" "Cancer enriched" "Detected in some" 21 "melanoma: 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SK-MEL-30: 35.9;WM-115: 63.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056332 Uncertain NA NA 320000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA056332: AB_2683102" "unprognostic (1.63e-2)" "unprognostic (2.63e-2)" "unprognostic (4.26e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (3.14e-2)" "unprognostic (1.93e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.39e-2)" "unprognostic (9.33e-2)" "unprognostic (2.25e-2)" "unprognostic (4.58e-3)" "unprognostic (8.16e-3)" "unprognostic (8.21e-2)" "unprognostic (1.56e-5)" 2.3 4.2 3.3 3.1 11.4 0.1 1.3 4.4 7.2 6.7 0.0 19.4 2.2 0.9 1.6 3.0 1.9 2.6 37.1 4.7 5.3 0.4 4.1 1.2 0.1 8.8 7.4 1.1 1.2 0.1 0.4 2.9 7.5 4.2 2.8 0.1 3.4 4.1 4.2 1.9 5.4 1.7 2.7 2.2 4.9 0.7 7.7 0.1 1.0 1.2 0.0 5.2 5.9 18.4 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.1 0.0 0.0 35.9 0.1 1.5 0.0 0.0 0.1 0.3 0.2 0.1 4.0 0.2 0.0 0.1 0.1 63.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 11.4 4.4 7.2 4.7 5.3 8.8 7.4 7.5 2.7 7.7 18.4 0.0 0.0 0.0 1.0 0.0 1.1 0.3 0.2 2.8 0.0 1.1 0.3 9.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 2.8 0.0 0.0 60.1 0.0 0.0 0.0 0.0 12.5 0.3 0.0 0.0 0.5 0.0 2.0 0.6 1.0 0.2 5.3 0.1 44.4 0.0 0.0 0.0 0.0 57.8 192.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 3.6 2.7 0.9 0.3 0.3 0.0 0.1 0.0 0.0 0.4 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 TMX3 "FLJ20793, KIAA1830, PDIA13, TXNDC10" ENSG00000166479 "Thioredoxin related transmembrane protein 3" Q96JJ7 18 68673688-68715108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014157 Uncertain "Intracellular and membrane" NA NA 36000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA014157: AB_1858469" "unprognostic (2.11e-1)" "unprognostic (5.15e-2)" "unprognostic (2.14e-2)" "unprognostic (9.47e-2)" "unprognostic (6.82e-2)" "unprognostic (7.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.54e-1)" "unprognostic (3.21e-3)" "unprognostic (5.20e-2)" "unprognostic (9.83e-3)" "unprognostic (2.73e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.69e-2)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" 22.7 16.2 11.7 24.1 13.0 14.1 19.2 14.2 15.4 15.0 9.9 12.7 18.2 16.6 20.4 14.1 13.8 16.5 20.8 13.5 13.2 14.6 16.2 19.5 27.9 11.1 11.2 13.0 11.9 15.9 9.6 19.8 12.1 17.7 16.3 26.0 10.6 13.0 11.0 16.7 18.8 21.0 11.4 22.6 14.0 11.4 12.1 23.3 17.7 21.0 22.7 20.1 11.2 11.5 11.1 17.4 32.9 25.9 66.6 70.7 24.5 85.7 91.0 61.0 67.7 8.4 31.9 31.4 16.6 125.4 25.9 40.8 21.9 42.9 92.8 30.3 19.6 28.8 27.4 14.7 70.6 62.0 45.7 56.5 27.1 66.2 59.2 61.8 78.4 27.0 18.9 42.5 73.1 6.9 33.3 19.6 13.9 9.1 28.2 30.7 65.5 38.5 51.7 24.2 31.5 24.5 42.0 26.7 31.8 32.4 17.6 52.1 76.4 108.4 30.0 24.7 63.6 28.4 30.4 29.4 65.5 50.1 81.3 2.2 2.9 2.4 3.8 4.7 5.5 3.1 3.9 3.6 4.7 2.1 4.3 4.4 0.7 4.9 3.3 6.4 4.4 2.7 11.7 13.0 14.2 15.4 13.5 13.2 11.1 11.2 12.1 11.4 12.1 11.5 31.4 28.9 27.8 36.2 25.0 20.3 17.2 17.6 12.0 29.1 21.0 15.6 25.1 10.0 18.8 16.5 18.8 15.0 44.3 10.6 1.9 15.2 8.9 18.7 38.5 27.3 18.0 17.0 77.9 10.2 20.8 34.5 13.3 25.6 20.3 24.2 34.2 26.6 18.6 26.9 45.6 13.8 14.2 23.3 26.8 3.3 24.2 23.9 24.9 32.8 18.2 20.5 20.6 49.8 53.1 15.4 15.4 16.6 29.8 19.4 17.5 8.0 28.8 32.5 39.5 23.6 32.0 23.8 28.3 21.7 24.3 12.4 23.3 22.9 9.4 16.6 CCDC102B "ACY1L, AN, C18orf14, FLJ23594, HsT1731" ENSG00000150636 "Coiled-coil domain containing 102B" Q68D86 18 68715209-69055189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 28.4" "Cell type enhanced" "Detected in many" "Astrocytes: 72.8;Early spermatids: 138.2;Excitatory neurons: 80.8;Late spermatids: 83.3;Oligodendrocytes: 90.1;Sertoli cells: 78.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 9.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 9.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 14.2;BJ hTERT+: 29.0;fHDF/TERT166: 26.2;HSkMC: 15.4;Karpas-707: 10.2" "HPA040623, HPA048194" Approved Approved Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria Cytosol "HPA040623: AB_10805715, HPA048194: AB_2680309" "unprognostic (3.92e-2)" "unprognostic (1.62e-1)" "unprognostic (5.58e-2)" "unprognostic (9.50e-3)" "unprognostic (7.13e-2)" "unprognostic (3.50e-1)" "unprognostic (7.87e-3)" "unprognostic (1.36e-1)" "unprognostic (5.59e-2)" "unprognostic (8.62e-3)" "unprognostic (1.95e-1)" "unprognostic (6.04e-2)" "prognostic unfavorable (2.90e-6)" "unprognostic (2.21e-2)" "unprognostic (2.12e-2)" "unprognostic (8.00e-3)" "unprognostic (3.13e-3)" 7.1 2.9 1.5 3.7 1.8 0.7 2.7 0.6 3.5 2.8 0.0 3.8 1.5 1.7 1.1 3.4 1.8 13.6 3.2 1.3 2.0 4.3 1.7 14.3 8.6 2.6 1.6 0.9 1.5 2.6 0.9 28.4 3.1 1.2 4.5 2.2 1.3 1.3 0.6 1.0 2.6 3.7 2.0 2.2 3.6 2.0 2.3 1.5 5.2 1.1 2.0 10.6 1.5 3.6 0.0 0.0 4.0 0.3 3.6 14.2 0.2 0.8 29.0 0.3 0.5 0.1 0.4 0.1 0.6 26.2 0.5 0.4 0.1 0.2 0.4 1.2 0.4 0.8 0.0 1.3 7.0 0.1 0.4 15.4 0.6 0.4 3.5 0.6 0.2 2.0 0.0 10.2 2.4 0.0 0.6 0.3 0.8 0.2 0.5 1.3 0.2 0.5 0.1 0.0 1.7 1.5 0.1 0.0 0.1 1.6 0.3 1.3 4.0 0.6 0.2 0.2 0.3 4.4 0.3 0.8 2.1 1.7 2.5 0.0 0.1 0.3 1.0 0.2 0.9 0.5 0.6 0.8 0.2 0.6 1.8 1.1 0.0 1.0 0.2 9.1 0.3 0.3 1.5 1.8 0.6 3.5 1.3 2.0 2.6 1.6 3.1 2.0 2.3 3.6 11.5 0.0 2.2 72.8 4.4 0.6 0.8 0.8 0.6 6.4 2.7 2.9 10.0 0.0 2.1 3.7 6.2 0.8 12.4 0.4 5.9 0.7 138.2 2.9 6.7 6.8 0.0 3.0 80.8 1.8 0.6 15.3 0.0 1.1 2.5 5.7 8.6 0.8 3.2 6.7 33.6 0.2 0.0 1.9 1.8 83.3 32.3 3.3 0.0 44.0 2.1 11.9 7.2 36.2 90.1 0.2 2.6 9.1 2.2 0.4 0.3 5.3 1.5 13.4 78.9 3.8 37.3 1.9 5.7 0.7 0.6 0.3 3.8 3.7 0.4 0.6 DOK6 "DOK5L, HsT3226, MGC20785" ENSG00000206052 "Docking protein 6" Q6PKX4 18 69400888-69849087 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.8;parathyroid gland: 12.5;retina: 22.3" "Group enriched" "Detected in many" 4 "Bipolar cells: 230.4;Excitatory neurons: 236.8;Inhibitory neurons: 259.1;Oligodendrocyte precursor cells: 178.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.5;Hep G2: 11.1;RPMI-8226: 10.5;SCLC-21H: 4.7;SH-SY5Y: 10.5;SuSa: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041099, HPA063534" Approved Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 56: Bipolar cells - Visual perception" "Focal adhesion sites, Cytosol" "HPA041099: AB_2677299, HPA063534: AB_2685032" "unprognostic (5.83e-2)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (1.55e-1)" "unprognostic (1.90e-2)" "unprognostic (8.62e-2)" "unprognostic (5.99e-2)" "unprognostic (1.04e-2)" "unprognostic (4.60e-3)" "unprognostic (2.13e-4)" "unprognostic (2.30e-3)" "unprognostic (2.88e-2)" "unprognostic (4.49e-3)" "unprognostic (1.09e-3)" 1.1 0.7 8.8 0.7 10.3 0.1 0.5 0.9 14.0 1.8 0.0 0.6 0.3 1.5 0.5 0.7 0.7 3.2 6.2 17.8 10.6 4.9 2.4 2.4 0.5 10.9 11.6 2.2 0.2 12.5 0.7 5.9 9.7 1.3 0.5 22.3 0.8 2.1 0.1 0.5 0.5 2.5 4.1 0.9 0.7 1.5 6.5 0.1 2.2 0.6 0.5 3.1 1.1 5.8 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.0 11.1 0.3 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 10.5 0.0 0.0 4.7 10.5 0.0 0.0 0.0 7.6 0.0 0.0 0.0 4.0 0.6 0.0 1.5 0.3 0.0 0.0 3.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 10.3 0.9 14.0 17.8 10.6 10.9 11.6 9.7 4.1 6.5 5.8 0.5 0.0 0.0 9.8 0.0 0.3 0.1 0.0 0.0 230.4 0.1 0.0 9.1 0.0 1.3 0.0 14.6 0.0 1.2 0.0 1.9 0.0 45.3 0.4 13.3 1.5 0.0 0.0 236.8 0.0 0.0 6.7 0.0 0.3 0.0 17.2 0.0 0.9 0.0 10.1 259.1 0.0 0.0 0.3 0.8 30.6 1.5 2.1 0.0 8.4 0.1 6.9 2.1 178.4 6.4 0.0 0.0 6.8 0.7 0.1 0.0 9.6 0.0 14.6 0.0 0.4 5.5 0.9 1.1 0.1 0.6 0.0 1.2 4.9 0.0 0.1 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 69.3;Oligodendrocyte precursor cells: 48.7;Oligodendrocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTERT-HME1: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041343, HPA041967, HPA075089" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Centrosome "HPA041343: AB_10794409, HPA041967: AB_10796790, HPA075089: " "unprognostic (1.76e-1)" "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.11e-2)" "unprognostic (3.44e-2)" "unprognostic (6.16e-3)" "unprognostic (4.63e-3)" "unprognostic (2.36e-1)" "unprognostic (1.40e-1)" "unprognostic (4.66e-2)" "unprognostic (1.90e-1)" "unprognostic (8.25e-2)" "unprognostic (6.94e-3)" "unprognostic (1.07e-1)" "unprognostic (3.81e-1)" "unprognostic (1.32e-1)" "unprognostic (1.96e-2)" 1.4 1.2 3.5 1.6 5.0 3.1 2.1 3.6 3.4 1.5 2.1 1.3 1.1 1.8 1.5 1.1 1.6 1.2 2.8 2.6 3.0 2.3 2.7 1.6 2.2 4.5 4.0 2.7 1.8 1.7 0.8 1.6 5.1 1.1 1.5 4.1 1.3 0.6 1.8 1.3 1.3 1.0 4.2 2.0 1.3 3.3 6.0 3.6 0.9 1.1 1.9 0.9 1.1 7.1 4.4 6.6 9.4 2.7 1.8 2.0 3.9 7.5 3.4 6.8 7.0 2.5 2.5 3.8 1.0 4.7 6.0 5.4 6.9 11.0 11.1 13.1 3.0 4.1 5.9 3.1 1.3 7.7 4.0 1.6 10.9 7.2 21.2 3.1 4.2 5.8 4.3 8.4 6.1 2.0 7.4 2.1 1.8 1.0 5.8 6.0 8.6 3.9 1.1 3.2 4.0 4.3 4.6 2.6 2.8 6.2 2.8 4.4 3.4 8.8 2.3 3.1 5.7 4.1 3.8 7.8 5.1 4.9 6.0 0.2 0.2 0.1 0.2 0.0 0.4 0.6 0.4 0.3 0.0 0.2 0.6 0.3 0.1 0.3 0.0 0.2 0.3 0.1 3.5 5.0 3.6 3.4 2.6 3.0 4.5 4.0 5.1 4.2 6.0 7.1 6.1 0.0 8.6 19.6 7.1 1.5 1.7 10.1 1.8 8.2 3.9 3.9 5.0 1.5 5.7 0.0 0.0 4.0 4.9 2.9 0.0 1.1 10.6 6.0 5.2 3.4 0.0 4.2 25.4 1.6 1.9 4.0 6.1 6.0 5.1 10.9 1.8 3.7 2.3 16.8 25.8 1.5 2.0 1.3 1.4 3.2 2.1 3.3 0.0 69.3 1.3 1.9 3.1 48.7 110.8 2.0 2.4 1.9 14.7 1.1 2.2 4.1 1.7 9.7 13.1 5.1 4.0 10.6 6.7 3.5 1.7 3.0 5.8 2.5 2.6 2.3 SOCS6 "CIS4, Cish4, HSPC060, SOCS4, SSI4, STAI4, STATI4" ENSG00000170677 "Suppressor of cytokine signaling 6" O14544 18 70289045-70330199 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.6;myeloid DC: 3.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010189 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles" Cytosol "CAB010189: AB_661195" "unprognostic (1.76e-3)" "unprognostic (6.83e-3)" "unprognostic (8.90e-3)" "unprognostic (4.52e-2)" "unprognostic (1.01e-1)" "unprognostic (2.07e-1)" "unprognostic (2.07e-1)" "unprognostic (7.93e-2)" "unprognostic (5.83e-2)" "unprognostic (1.75e-1)" "unprognostic (6.90e-2)" "unprognostic (8.19e-2)" "prognostic favorable (1.02e-4)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" "unprognostic (4.11e-2)" "unprognostic (1.80e-2)" 7.9 8.0 8.3 6.0 10.2 13.1 14.0 11.7 8.1 15.2 5.8 16.2 15.6 11.8 6.9 15.0 12.3 13.5 11.0 7.8 7.6 9.3 28.3 9.7 3.4 14.8 10.2 10.9 13.0 14.1 4.1 13.9 14.4 8.4 14.4 5.6 11.3 7.9 12.8 7.1 22.8 10.9 13.2 4.1 14.0 5.7 17.5 3.2 11.6 13.4 5.6 8.3 8.0 19.3 19.2 41.6 17.4 12.0 16.1 18.9 19.4 40.3 24.5 24.0 18.0 15.6 31.7 2.1 3.6 37.7 29.0 22.2 12.8 13.2 23.3 0.0 7.8 14.4 14.3 24.1 19.1 7.9 15.6 15.3 15.4 20.9 17.4 23.9 12.2 1.7 8.7 9.6 16.5 9.3 6.8 5.8 11.2 12.2 17.7 8.0 16.8 3.5 14.9 15.6 8.0 20.0 20.9 22.8 18.9 12.4 6.8 13.6 15.1 26.3 13.3 5.5 16.5 0.0 0.0 5.2 29.3 0.6 18.1 0.0 3.6 2.9 0.2 0.7 0.1 0.3 0.4 0.0 3.9 0.0 0.6 0.3 0.0 1.0 0.0 0.3 0.0 1.2 8.3 10.2 11.7 8.1 7.8 7.6 14.8 10.2 14.4 13.2 17.5 19.3 15.0 25.6 17.0 8.1 1.2 11.7 13.7 13.3 12.0 12.9 26.6 14.7 22.4 21.5 30.1 11.0 6.2 28.0 2.1 61.0 11.7 18.4 1.3 23.5 23.5 13.9 29.4 3.8 17.0 18.5 15.6 13.7 21.4 34.6 31.0 9.1 13.6 32.4 25.7 37.0 17.5 31.0 10.2 7.7 11.1 2.8 11.5 19.2 26.6 86.2 10.1 7.8 5.2 28.6 32.1 30.5 30.5 12.8 0.9 17.4 36.8 25.6 21.8 4.7 0.0 14.9 12.5 1.3 11.0 20.5 11.9 68.4 2.1 4.4 26.7 34.6 CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 32.5" "Cell type enriched" "Detected in some" 13 "Excitatory neurons: 508.3" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 54.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted in brain" NA NA 1400000 "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.03e-2)" "unprognostic (3.52e-1)" "unprognostic (1.13e-3)" "unprognostic (9.09e-5)" "unprognostic (7.10e-2)" "unprognostic (6.27e-3)" "unprognostic (7.39e-2)" "unprognostic (2.17e-1)" "unprognostic (1.37e-4)" "unprognostic (5.01e-4)" "unprognostic (8.15e-2)" "unprognostic (6.07e-4)" "unprognostic (7.19e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (4.93e-2)" 0.4 0.2 7.9 0.3 17.3 0.0 0.1 0.0 32.5 0.3 0.0 1.8 1.5 0.0 0.0 0.0 0.1 0.0 0.1 3.3 0.2 2.5 0.4 0.0 0.0 5.9 4.5 0.1 0.0 0.0 0.2 0.0 8.7 0.9 1.5 5.1 0.0 5.1 0.0 0.8 2.5 0.8 0.0 0.0 0.1 0.2 13.8 0.0 0.0 0.0 0.7 0.1 0.0 12.8 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 54.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 17.3 0.0 32.5 3.3 0.2 5.9 4.5 8.7 0.0 13.8 12.8 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.7 0.3 37.8 0.0 508.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 0.0 0.3 0.6 0.6 0.0 0.0 10.3 0.0 0.5 0.0 9.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 NETO1 "BCTL1, BTCL1" ENSG00000166342 "Neuropilin and tolloid like 1" Q8TDF5 18 72742314-72868146 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 21.9;retina: 34.6" "Group enriched" "Detected in some" 14 "Bipolar cells: 206.4;Excitatory neurons: 307.1;Inhibitory neurons: 345.9;Oligodendrocyte precursor cells: 172.4" "Cancer enhanced" "Detected in some" "glioma: 1.2" "Group enriched" "Detected in many" 41 "amygdala: 6.6;basal ganglia: 12.4;cerebral cortex: 21.9;hippocampal formation: 17.5;white matter: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 21.9;REH: 20.6;RPMI-8226: 32.7;RT4: 24.7;SCLC-21H: 26.9;U-2 OS: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA064630 Approved "Golgi apparatus" "Secreted in brain" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA064630: AB_2685305" "unprognostic (4.02e-2)" "unprognostic (4.08e-3)" "unprognostic (2.75e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-2)" "unprognostic (1.35e-5)" "unprognostic (4.05e-1)" "unprognostic (4.73e-2)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (6.63e-2)" "unprognostic (1.20e-1)" "unprognostic (1.73e-2)" "unprognostic (3.70e-2)" "unprognostic (3.35e-2)" "unprognostic (1.59e-1)" "unprognostic (9.13e-3)" 1.2 0.0 6.6 0.3 12.4 0.1 1.0 0.0 21.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.7 17.5 0.0 0.1 0.0 0.0 1.0 0.3 0.0 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.1 34.6 0.2 0.0 0.0 0.3 0.5 0.0 0.0 3.1 0.2 0.8 0.2 0.4 0.6 0.0 1.2 0.1 0.0 16.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 8.7 0.0 0.0 20.6 0.0 32.7 4.0 24.7 26.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 12.4 0.0 21.9 17.5 0.0 0.3 0.0 0.3 0.0 0.2 16.3 2.0 0.0 0.0 16.6 6.1 0.0 0.0 0.0 0.0 206.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 307.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 345.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 17.8 0.0 2.2 0.0 172.4 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FBXO15 "FBX15, MGC39671" ENSG00000141665 "F-box protein 15" Q8NCQ5 18 74073353-74147843 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 4.1;testis: 7.1" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Endometrial ciliated cells: 41.1;Oligodendrocytes: 19.3;Respiratory ciliated cells: 59.2;Spermatocytes: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.6" "Lineage enriched" "Detected in single" 6 "T-cells: 1.6" "Cell line enhanced" "Detected in some" "GAMG: 1.6;JURKAT: 2.6;SCLC-21H: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "basal ganglia: 17.6" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.69e-2)" "unprognostic (1.97e-1)" "unprognostic (6.34e-6)" "unprognostic (1.65e-2)" "unprognostic (4.20e-1)" "unprognostic (6.77e-2)" "unprognostic (1.64e-1)" "unprognostic (5.93e-2)" "unprognostic (1.27e-1)" "unprognostic (3.38e-2)" "unprognostic (1.00e-2)" "unprognostic (9.62e-2)" "unprognostic (4.46e-5)" "unprognostic (4.64e-2)" "unprognostic (3.35e-2)" "unprognostic (1.62e-4)" "unprognostic (2.87e-1)" 0.1 0.7 0.9 0.0 1.2 0.1 0.3 1.0 1.1 0.5 1.1 0.1 0.1 0.1 2.2 0.1 4.1 0.2 0.1 1.0 1.1 1.1 0.4 0.4 0.1 2.6 3.4 0.3 0.4 0.6 1.4 0.0 2.4 0.2 0.0 3.4 0.3 0.7 0.1 0.2 0.1 0.0 1.8 0.3 0.2 7.1 0.9 0.2 0.6 0.0 0.0 0.1 0.1 2.9 0.0 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.7 0.0 0.0 0.3 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.3 0.3 0.0 2.6 0.0 0.2 0.1 0.1 0.1 0.1 0.5 0.3 0.8 0.3 0.0 0.0 0.3 0.0 2.7 0.8 0.0 0.0 1.0 0.3 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 1.2 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.2 0.0 0.2 1.6 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.9 1.2 1.0 1.1 1.0 1.1 2.6 3.4 2.4 1.8 0.9 2.9 0.3 6.4 1.1 12.4 1.0 0.3 0.8 3.9 0.0 8.1 1.5 1.8 0.6 0.0 5.9 1.8 0.0 0.5 0.1 0.1 3.9 0.9 36.0 41.1 0.5 0.3 0.0 0.4 6.4 0.2 0.7 0.2 0.0 1.2 0.0 2.2 0.7 0.4 3.1 5.0 8.8 0.2 0.0 0.6 0.3 17.8 1.2 0.4 0.0 2.8 0.0 7.8 0.0 9.0 19.3 0.1 0.1 1.5 0.0 0.2 0.0 5.8 59.2 10.3 0.0 0.8 2.1 41.5 11.7 0.0 0.0 0.4 0.4 0.3 0.2 0.6 TIMM21 "C18orf55, HSPC154, TIM21" ENSG00000075336 "Translocase of inner mitochondrial membrane 21" Q9BVV7 18 74148523-74160531 "Predicted membrane proteins" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010587, HPA051543" Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA010587: AB_1851244, HPA051543: AB_2681528" "unprognostic (4.88e-1)" "unprognostic (2.20e-2)" "unprognostic (1.16e-1)" "unprognostic (8.61e-2)" "unprognostic (3.81e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (9.22e-5)" "unprognostic (1.42e-1)" "unprognostic (1.59e-2)" "unprognostic (1.93e-2)" "unprognostic (4.79e-3)" "unprognostic (1.55e-3)" "prognostic favorable (1.38e-9)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.31e-1)" "unprognostic (6.66e-2)" 13.8 14.6 22.7 10.1 23.8 8.1 10.6 25.7 29.6 9.7 23.0 16.2 12.2 10.4 11.9 13.3 9.5 5.6 48.7 22.8 23.2 21.0 22.3 7.4 9.9 22.9 22.5 11.9 9.6 18.0 11.4 10.0 23.0 12.2 13.5 14.8 10.2 9.9 50.8 11.1 11.5 9.5 22.6 13.8 12.4 7.0 23.1 7.7 12.4 47.9 10.1 12.6 10.2 24.3 25.6 26.6 24.4 30.2 19.7 17.4 35.9 38.5 12.8 22.8 19.2 19.5 18.3 34.2 12.1 15.0 19.1 41.6 34.0 32.8 38.1 21.7 19.6 14.7 46.2 53.9 10.0 55.6 23.7 16.2 19.4 29.0 19.9 18.6 17.5 19.0 30.2 23.2 27.9 25.6 29.6 45.6 23.5 15.3 48.6 27.5 28.2 42.6 30.2 35.5 25.9 14.2 14.5 35.9 23.8 19.1 24.9 28.6 12.6 53.3 37.9 17.5 40.3 7.3 60.3 37.2 26.0 59.7 38.0 8.7 9.8 6.3 12.7 15.6 15.2 16.0 12.2 10.7 13.2 12.3 15.3 17.6 1.2 17.1 18.2 15.7 10.0 8.8 22.7 23.8 25.7 29.6 22.8 23.2 22.9 22.5 23.0 22.6 23.1 24.3 8.0 12.8 17.8 8.1 12.1 8.0 9.3 30.2 21.6 17.1 9.0 12.6 165.5 14.3 16.7 5.5 6.2 29.4 10.2 9.4 54.8 13.2 3.1 7.3 13.5 13.1 14.4 16.2 8.6 9.4 28.3 19.0 14.8 6.7 9.5 12.6 11.7 20.2 18.8 16.8 11.1 11.5 8.2 11.7 3.5 1.5 11.5 8.5 1.8 6.5 13.4 20.0 9.2 8.5 9.2 9.1 6.2 12.4 25.7 10.5 12.5 34.5 15.0 20.1 6.6 15.0 16.5 12.8 12.7 20.2 8.0 16.4 7.5 12.9 18.2 7.7 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 C18orf63 DKFZP781G0119 ENSG00000206043 "Chromosome 18 open reading frame 63" Q68DL7 18 74315839-74359189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 9.8" "Cell type enriched" "Detected in some" 10 "Spermatocytes: 83.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042233 Approved Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA042233: AB_10960843" "unprognostic (1.40e-1)" "unprognostic (1.43e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.7 7.9 0.0 0.0 0.0 0.0 0.1 0.1 0.0 DIPK1C "C18orf51, FAM69C" ENSG00000187773 "Divergent protein kinase domain 1C" Q0P6D2 18 74434775-74457944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 28.6;choroid plexus: 11.3;retina: 16.5" "Cell type enriched" "Detected in single" 27 "Cardiomyocytes: 22.1" "Group enriched" "Detected in some" 18 "glioma: 11.1;melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "SK-MEL-30: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048928 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA048928: AB_2680560" "unprognostic (6.35e-2)" "unprognostic (1.13e-2)" "unprognostic (8.09e-2)" "unprognostic (3.32e-2)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (1.43e-2)" "unprognostic (1.10e-1)" "unprognostic (3.31e-1)" "unprognostic (8.97e-2)" "unprognostic (2.43e-1)" "unprognostic (4.10e-2)" "unprognostic (1.91e-4)" "unprognostic (2.16e-1)" "unprognostic (6.73e-2)" "unprognostic (3.23e-2)" "unprognostic (4.40e-3)" 0.3 0.1 19.6 0.0 26.4 0.0 0.3 21.4 25.8 1.6 11.3 1.4 0.0 0.2 0.1 0.1 0.2 0.4 8.4 18.6 20.6 0.1 0.3 0.0 0.0 19.7 24.4 0.0 0.1 0.0 0.3 0.1 19.2 0.4 0.1 16.5 0.3 0.6 1.1 4.2 0.3 0.1 16.5 0.1 1.5 6.8 26.0 0.7 0.0 2.0 0.0 0.1 0.4 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 26.4 21.4 25.8 18.6 20.6 19.7 24.4 19.2 16.5 26.0 28.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CNDP2 "CN2, CPGL, FLJ10830, HsT2298, PEPA" ENSG00000133313 "Carnosine dipeptidase 2" Q96KP4 18 74495816-74523454 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 334.7;Proximal enterocytes: 629.1;Proximal tubular cells: 487.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 458.7;RPMI-8226: 616.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026196, HPA036898, HPA036899" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 2600000 "Cluster 27: Non-specific - Gene expression" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "CAB026196: , HPA036898: AB_2675370, HPA036899: AB_2675371" "unprognostic (2.81e-2)" "unprognostic (9.96e-2)" "unprognostic (3.28e-1)" "unprognostic (1.19e-3)" "unprognostic (2.57e-2)" "unprognostic (5.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.49e-1)" "unprognostic (9.31e-2)" "unprognostic (1.56e-3)" "unprognostic (1.15e-1)" "prognostic favorable (3.50e-6)" "unprognostic (2.37e-3)" "unprognostic (4.65e-3)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" 54.8 40.7 125.3 75.0 147.0 25.1 60.4 139.4 156.9 136.8 113.0 83.6 190.1 44.2 122.8 78.4 140.8 94.4 63.7 123.7 133.2 327.3 261.1 82.3 86.3 143.1 137.4 34.4 100.7 58.5 48.0 75.4 144.7 122.5 79.5 42.1 57.4 101.7 26.6 47.0 255.0 37.9 140.4 137.0 103.5 20.9 143.9 52.5 159.1 22.4 82.2 94.5 47.4 157.6 64.6 85.0 60.5 57.4 72.2 42.5 252.3 66.0 61.7 88.3 87.4 49.6 67.1 80.3 81.4 72.1 69.0 95.0 92.7 124.9 62.7 121.3 36.7 80.2 42.1 79.6 104.6 158.7 119.3 64.5 93.9 76.4 136.6 50.1 78.3 94.6 86.3 458.7 59.1 71.6 84.9 75.6 91.0 42.4 50.3 91.3 69.4 616.6 346.1 264.1 65.3 34.2 51.6 360.2 91.6 143.0 151.5 64.0 82.5 93.9 79.5 21.2 45.2 85.5 380.6 108.1 63.6 113.8 80.2 37.1 115.4 49.0 77.6 166.3 84.4 102.4 61.6 72.2 185.1 110.5 65.5 72.4 15.9 124.6 174.1 161.3 94.5 135.7 125.3 147.0 139.4 156.9 123.7 133.2 143.1 137.4 144.7 140.4 143.9 157.6 39.2 73.7 62.7 16.6 55.7 9.2 40.3 48.6 12.5 33.6 76.5 36.4 26.9 77.2 56.8 119.5 16.7 157.9 47.8 99.0 187.9 168.1 3.3 187.7 49.7 49.6 65.3 23.3 8.8 154.7 130.9 23.5 63.7 334.7 12.0 34.0 40.0 119.8 216.3 43.7 10.8 82.9 75.3 122.9 24.9 4.1 18.6 79.0 17.8 13.1 90.8 86.6 55.6 15.6 51.7 108.9 103.5 16.6 44.4 65.2 629.1 487.6 73.3 31.6 13.1 15.2 22.3 8.3 7.2 27.1 9.7 109.0 38.2 32.8 99.8 53.8 CNDP1 "CN1, CPGL2, HsT2308, MGC10825" ENSG00000150656 "Carnosine dipeptidase 1" Q96KN2 18 74534500-74587212 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 85.6" "Cell type enriched" "Detected in some" 10 "Oligodendrocytes: 361.7" "Cancer enhanced" "Detected in some" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 38 "U-266/84: 15.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008933, HPA073283" Enhanced "Secreted to blood" NA NA 2100000000 "Cluster 70: Brain - Nervous system development" "Cluster 16: U-266 - Nucleosome" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008933: AB_1847033, HPA073283: " "unprognostic (7.43e-3)" "unprognostic (6.00e-2)" "unprognostic (8.55e-3)" "unprognostic (3.93e-1)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (8.04e-3)" "unprognostic (1.12e-2)" "unprognostic (2.81e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "unprognostic (6.90e-3)" "unprognostic (1.14e-1)" "unprognostic (3.30e-2)" "unprognostic (1.33e-1)" "unprognostic (1.28e-1)" 0.0 0.0 27.4 0.0 74.2 0.1 0.0 80.4 39.0 0.0 6.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 30.5 51.3 0.5 12.9 0.0 0.0 85.6 76.9 0.0 0.0 0.0 0.2 0.0 74.3 0.1 0.0 0.1 0.0 0.1 1.4 0.1 0.2 0.0 39.7 0.0 0.0 0.3 74.9 0.0 0.2 0.0 0.0 0.0 0.0 80.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 15.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 27.4 74.2 80.4 39.0 30.5 51.3 85.6 76.9 74.3 39.7 74.9 80.7 0.2 0.0 0.0 0.3 0.2 0.1 0.4 0.2 0.0 0.6 0.5 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 8.6 0.5 0.2 0.2 0.0 2.7 1.2 0.2 0.0 0.3 0.0 1.5 0.0 0.2 0.7 35.1 0.1 0.0 1.5 0.7 0.0 1.2 1.1 3.1 0.0 0.2 0.0 1.0 0.0 0.5 0.0 3.0 361.7 0.2 0.1 0.0 0.0 0.4 0.4 24.5 0.0 1.0 0.0 0.6 0.2 1.0 0.4 0.0 0.3 0.0 0.4 0.0 0.5 0.2 ZNF407 "FLJ13839, FLJ20307, KIAA1703" ENSG00000215421 "Zinc finger protein 407" Q9C0G0 18 74597870-75065671 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 96.9;Excitatory neurons: 111.0;Inhibitory neurons: 100.2;Microglial cells: 113.4;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028255, HPA041673" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA028255: AB_10603466, HPA041673: AB_2677610" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (2.48e-1)" "unprognostic (8.62e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-2)" "unprognostic (1.76e-2)" "unprognostic (4.31e-1)" "unprognostic (1.19e-3)" "unprognostic (4.04e-4)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "prognostic favorable (9.79e-5)" "unprognostic (8.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.11e-2)" 2.4 1.9 2.9 3.1 3.5 5.3 2.9 8.0 2.8 2.7 8.6 2.8 2.2 3.7 1.9 2.5 2.7 2.1 3.2 2.3 2.9 2.4 2.2 2.4 3.3 3.6 3.0 4.8 2.2 3.9 1.5 2.7 4.1 2.8 2.2 2.9 2.4 2.8 3.9 2.3 2.4 3.1 2.9 3.4 2.3 4.0 3.2 5.5 3.6 3.6 3.0 2.4 2.0 4.1 3.9 4.0 4.4 4.1 3.2 4.7 3.2 5.1 4.4 3.7 4.0 1.7 2.2 5.6 1.5 7.1 2.5 4.5 4.2 5.5 5.4 9.3 2.6 7.1 5.5 3.2 2.9 10.9 6.0 4.3 2.4 5.9 5.1 3.5 5.6 3.9 4.1 8.0 5.7 3.1 5.3 1.5 2.6 1.4 3.6 5.4 5.8 4.4 2.6 7.2 4.2 4.0 4.7 2.9 3.6 3.2 3.4 4.6 7.9 8.3 3.5 2.3 4.1 2.8 6.2 5.7 3.0 4.6 5.0 1.6 0.7 0.9 1.0 0.9 1.0 0.8 0.8 0.6 0.3 0.8 0.9 1.1 2.2 1.1 0.6 1.3 0.2 0.4 2.9 3.5 8.0 2.8 2.3 2.9 3.6 3.0 4.1 2.9 3.2 4.1 16.5 6.4 6.3 96.9 10.6 3.2 5.0 3.0 2.8 11.2 6.3 6.0 19.4 2.8 4.9 5.5 6.2 4.2 11.4 6.9 0.0 4.3 4.6 8.6 15.3 10.0 4.2 3.4 111.0 2.9 2.7 7.6 17.3 14.4 1.3 10.2 3.3 5.5 3.2 5.0 100.2 5.7 2.0 5.3 2.8 3.3 5.3 7.6 5.4 113.4 6.1 6.2 8.2 122.6 130.5 4.8 6.0 4.5 11.1 4.4 4.3 2.6 6.2 13.2 6.6 10.8 8.1 9.0 12.8 5.6 4.1 5.2 10.1 12.1 6.0 3.9 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: AB_1858932, HPA053646: AB_2682216" "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.23e-1)" 17.7 12.9 15.6 11.8 17.8 20.7 22.2 19.2 22.0 18.8 14.0 26.3 19.0 15.5 24.8 20.0 17.9 15.8 34.3 17.0 12.9 24.2 32.5 16.3 19.3 16.8 13.9 23.9 26.6 24.7 21.5 36.6 18.3 17.1 28.7 30.6 23.8 18.2 44.9 22.0 26.0 15.2 16.5 16.1 21.3 7.0 15.5 23.3 27.8 40.7 20.6 16.6 16.9 16.8 21.7 14.1 14.8 30.4 22.6 29.0 16.3 38.5 44.6 14.8 18.5 8.7 30.0 15.2 6.0 38.3 17.4 28.7 18.5 32.6 10.4 94.6 27.1 34.1 32.7 17.0 16.0 58.0 33.2 32.2 31.9 11.9 27.2 27.5 30.9 35.2 18.6 54.0 28.6 25.5 14.6 28.6 3.8 20.9 31.9 31.0 23.7 50.2 28.9 36.2 27.2 22.4 21.4 21.7 24.5 10.4 21.8 28.4 27.7 28.9 22.0 9.2 12.4 8.8 41.2 10.5 19.1 49.5 23.8 1.7 3.4 8.9 3.2 2.9 2.3 2.1 2.6 2.9 2.3 1.5 1.4 2.2 1.7 1.7 3.8 1.7 3.2 1.8 15.6 17.8 19.2 22.0 17.0 12.9 16.8 13.9 18.3 16.5 15.5 16.8 41.5 35.3 17.9 12.4 7.5 9.7 18.7 13.9 9.6 59.0 15.3 10.8 56.3 20.0 12.5 27.6 6.2 8.4 15.9 24.8 19.6 12.3 0.5 8.5 39.0 24.1 23.4 9.9 16.6 21.1 8.1 26.4 12.8 11.1 7.0 42.6 23.6 25.0 16.4 25.2 14.1 25.1 14.2 20.2 19.1 2.1 36.7 18.3 12.4 12.2 23.9 21.3 13.4 20.6 14.9 15.5 21.9 63.2 6.2 18.5 35.2 19.0 8.1 40.9 19.7 25.5 12.3 0.4 4.9 23.7 11.1 6.7 11.0 73.0 27.2 20.9 TSHZ1 "NY-CO-33, SDCCAG33, TSH1" ENSG00000179981 "Teashirt zinc finger homeobox 1" Q6ZSZ6 18 75210755-75289950 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 84.9;Peritubular cells: 187.3;Theca cells: 83.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 44.4" "Region enriched" "Detected in all" 5 "olfactory bulb: 115.6" "Low region specificity" "Detected in all" HPA006982 Approved Approved Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA006982: AB_1079886" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (4.03e-1)" "unprognostic (5.89e-2)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (1.24e-1)" "unprognostic (4.12e-2)" "unprognostic (9.05e-2)" "unprognostic (5.64e-2)" "unprognostic (1.69e-1)" "unprognostic (3.43e-3)" "unprognostic (1.26e-1)" "unprognostic (8.00e-2)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.42e-3)" 12.0 7.7 16.3 7.1 14.1 3.3 12.1 23.5 21.0 17.4 6.3 18.1 13.8 11.4 9.3 10.0 15.9 10.4 10.9 17.0 10.4 12.1 8.2 8.0 7.3 18.8 11.5 35.4 7.2 9.2 9.7 29.7 19.3 8.9 9.3 7.9 12.5 11.1 9.2 10.6 13.7 9.3 20.1 9.4 8.8 6.3 15.5 12.3 8.2 6.4 5.3 10.9 11.0 14.1 5.4 7.0 2.2 12.8 18.8 8.9 2.2 24.2 22.6 4.0 7.4 3.2 12.9 10.8 3.0 21.9 4.5 4.8 2.9 6.9 1.4 44.4 23.2 8.3 14.5 4.3 4.9 20.0 9.4 9.1 7.2 3.3 6.5 6.2 10.1 12.5 4.7 19.1 6.6 5.2 14.3 11.4 0.9 6.3 7.6 12.9 6.6 12.9 7.6 3.9 15.9 12.1 6.8 8.8 6.8 0.8 2.0 10.4 7.6 8.7 5.9 6.0 3.9 6.2 15.9 8.7 8.6 16.6 8.1 0.0 0.5 0.5 2.1 0.2 1.4 0.4 1.0 1.8 0.8 0.6 1.5 2.2 0.3 1.5 0.2 0.8 0.4 0.7 16.3 14.1 23.5 21.0 17.0 10.4 18.8 11.5 19.3 20.1 15.5 14.1 60.2 12.8 14.0 34.3 7.1 17.0 5.6 4.8 27.9 40.8 12.2 12.6 24.4 25.8 7.9 3.7 2.1 4.6 25.6 25.4 3.9 7.5 1.2 12.5 33.9 34.4 16.9 6.9 24.9 10.0 2.2 28.8 4.6 18.2 7.0 22.5 21.0 20.5 6.4 11.8 27.7 15.0 10.2 10.8 30.9 5.9 64.7 14.3 8.8 30.0 11.2 17.9 24.7 84.9 21.3 2.9 14.7 187.3 10.6 7.3 29.7 18.4 9.1 12.1 26.3 21.3 12.2 1.4 4.8 33.1 13.2 3.6 18.2 83.2 17.9 5.4 SMIM21 C18orf62 ENSG00000206026 "Small integral membrane protein 21" Q3B7S5 18 75409476-75427703 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 2.8" "Group enriched" "Detected in some" 67 "Early spermatids: 73.8;Late spermatids: 48.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.1" HPA041686 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA041686: AB_10961179" "unprognostic (7.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF516 "HsT287, KIAA0222" ENSG00000101493 "Zinc finger protein 516" Q92618 18 76357682-76495242 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 75.1;Early spermatids: 77.4;Endometrial stromal cells: 78.9;Langerhans cells: 69.7;Oligodendrocyte precursor cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 10.2" "Cell line enhanced" "Detected in many" "THP-1: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015792 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA015792: AB_1859314" "prognostic favorable (7.09e-4)" "unprognostic (7.28e-2)" "unprognostic (4.51e-1)" "unprognostic (1.22e-3)" "unprognostic (3.33e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.63e-3)" "unprognostic (3.14e-1)" "unprognostic (3.29e-2)" "prognostic favorable (7.96e-4)" "unprognostic (5.87e-2)" "prognostic favorable (1.21e-4)" "unprognostic (1.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.71e-1)" "unprognostic (2.02e-1)" 5.8 7.6 19.6 4.5 18.5 24.5 6.4 9.4 11.2 32.2 2.3 8.4 6.2 32.2 8.5 9.0 23.6 5.1 5.3 18.1 21.9 4.6 6.2 7.6 3.0 16.8 18.2 22.8 6.8 9.5 11.3 3.0 10.8 9.7 2.6 16.2 6.4 17.3 14.2 10.1 6.2 11.8 10.7 6.8 6.3 34.4 18.8 4.4 6.4 5.9 2.8 10.3 15.3 6.8 2.4 2.7 18.8 25.0 5.3 8.0 2.4 14.6 12.1 3.1 5.7 5.5 8.9 12.7 3.0 15.5 7.7 5.2 10.4 14.0 2.0 0.0 8.0 1.2 0.0 11.7 13.2 8.5 8.3 15.4 5.9 6.3 6.7 4.2 3.5 5.2 0.0 0.0 3.0 5.2 0.2 14.4 9.5 1.5 0.7 5.7 1.9 6.6 4.7 11.1 18.9 11.3 0.2 0.0 15.3 7.3 3.1 33.2 2.3 7.1 12.4 0.2 1.5 0.1 0.4 9.9 4.2 5.8 18.6 2.5 1.8 2.9 0.0 1.2 0.4 0.0 0.1 0.0 1.2 0.3 0.4 0.2 10.2 0.7 1.4 0.8 0.0 0.4 19.6 18.5 9.4 11.2 18.1 21.9 16.8 18.2 10.8 10.7 18.8 6.8 9.6 9.6 10.1 75.1 5.0 19.5 17.9 12.7 9.1 15.0 8.6 8.1 8.5 5.7 8.8 1.8 31.3 0.3 6.1 4.2 3.9 5.8 77.4 33.1 78.9 9.8 12.6 3.0 19.8 2.9 0.4 15.6 4.6 47.7 1.3 10.4 7.9 11.4 8.4 3.3 37.3 5.2 6.1 20.0 69.7 43.5 30.4 14.2 12.4 30.0 20.9 8.4 9.2 73.9 0.7 5.5 4.5 35.0 0.6 11.8 7.4 5.4 15.3 30.3 13.1 16.1 15.5 3.7 33.1 7.0 20.2 0.5 2.8 21.5 4.5 20.8 ZNF236 ENSG00000130856 "Zinc finger protein 236" Q9UL36 18 76822557-76972901 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008600 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cell Junctions" Cytosol "HPA008600: AB_1080696" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (3.13e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (9.88e-3)" "unprognostic (5.51e-2)" "unprognostic (1.77e-1)" "unprognostic (2.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "unprognostic (2.95e-2)" "unprognostic (9.40e-2)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" 2.5 2.2 3.2 2.2 5.3 4.9 2.4 9.2 4.4 3.0 0.0 2.8 1.9 3.2 2.8 2.5 2.9 2.0 2.3 3.4 4.3 2.0 2.1 2.1 2.6 2.3 3.5 4.3 2.8 3.1 3.6 2.2 2.6 2.6 1.5 2.4 2.7 2.3 2.5 4.1 2.5 2.1 1.4 2.3 2.8 6.8 3.5 4.1 2.6 3.1 2.4 2.6 2.9 5.7 2.5 2.4 4.7 3.4 3.7 3.4 1.9 1.8 2.6 2.9 2.4 2.3 2.3 3.6 0.9 2.5 3.2 4.6 3.0 2.8 2.5 3.8 3.1 3.4 3.9 2.8 2.1 5.7 3.7 3.4 3.1 2.8 4.4 3.4 3.0 5.5 3.3 2.9 3.1 2.2 6.9 3.2 2.5 0.6 2.6 4.3 4.9 2.4 2.4 3.8 2.6 2.8 3.6 2.2 2.5 2.2 2.5 3.9 3.2 5.3 2.0 1.3 2.9 2.0 3.0 4.4 3.6 3.0 3.9 0.7 2.0 3.9 3.1 1.9 3.0 5.9 2.3 2.1 1.4 4.4 2.6 2.7 2.1 1.9 1.8 2.8 2.7 0.9 3.2 5.3 9.2 4.4 3.4 4.3 2.3 3.5 2.6 1.4 3.5 5.7 9.3 9.6 7.9 39.5 11.9 7.1 8.5 5.4 10.8 15.3 8.0 7.6 9.5 12.8 6.7 7.3 10.4 8.4 12.9 5.6 1.9 5.4 6.9 10.8 12.6 9.3 6.0 12.8 37.7 3.9 7.2 8.8 9.2 10.5 1.3 15.8 10.0 6.8 6.0 25.2 25.3 5.0 6.1 7.2 7.2 6.0 10.5 8.7 7.2 16.9 8.4 9.7 9.2 41.7 39.7 4.7 3.1 7.2 9.1 6.8 5.9 3.0 10.9 15.9 6.6 14.2 10.4 26.7 26.2 8.8 8.4 6.0 12.4 7.8 5.7 6.3 MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 11 "Oligodendrocytes: 2895.5" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 99.3;SK-MEL-30: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" 27.3 7.1 15448.6 20.9 21296.6 43.0 20.9 19749.8 26916.8 17.3 9144.9 19.0 18.6 13.2 7.9 20.5 31.5 17.2 24.1 12696.6 16271.8 28.7 23.5 20.0 26.9 30812.9 22193.8 22.3 22.8 47.5 26.7 4.7 25986.2 15.3 16.9 7.5 22.0 13.0 140.8 28.7 20.7 8.7 23219.4 28.0 17.5 6.1 19406.0 12.5 22.2 81.6 27.8 19.0 20.2 30044.2 26.1 22.4 0.2 0.8 35.8 53.1 8.5 0.6 0.6 0.8 0.6 3.2 39.2 15.9 4.4 1.7 0.2 49.9 3.8 22.1 0.7 60.7 5.3 10.4 3.9 5.2 22.5 99.3 65.3 7.7 18.4 19.8 30.3 16.4 6.5 37.9 0.0 3.6 0.0 3.2 4.1 50.6 2.2 15.6 18.1 1.5 0.4 35.9 34.5 34.3 1.8 0.3 3.2 0.0 204.7 6.1 0.6 60.5 0.1 0.2 0.5 0.2 2.8 0.1 0.5 16.9 5.8 62.0 2.5 21.7 8.5 32.4 21.6 8.1 13.1 5.9 15.4 28.1 9.2 5.1 9.1 17.0 39.5 28.0 8.1 11.9 14.9 11.6 15448.6 21296.6 19749.8 26916.8 12696.6 16271.8 30812.9 22193.8 25986.2 23219.4 19406.0 30044.2 5.5 48.1 39.5 10.7 86.8 118.8 61.1 28.1 84.2 52.8 24.2 22.7 45.0 35.8 50.3 103.0 2.1 0.7 221.8 48.7 41.1 43.7 5.9 159.8 11.2 9.4 49.8 68.8 32.4 35.8 0.8 36.2 59.1 161.1 71.5 2.1 10.0 30.2 44.4 1.7 47.1 51.4 44.7 78.3 123.1 6.3 28.3 98.2 92.5 45.0 84.4 25.7 247.2 124.7 2895.5 60.4 25.5 14.3 45.3 117.6 37.5 36.0 54.0 6.1 0.0 88.7 8.4 7.7 1.1 75.6 154.7 0.7 151.6 0.0 42.1 103.7 GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;brain: 1.9;pituitary gland: 1.4" "Cell type enhanced" "Detected in some" "Early spermatids: 68.1;Enteroendocrine cells: 17.6;Oligodendrocyte precursor cells: 42.7;Respiratory ciliated cells: 11.7" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in many" HPA074584 Supported "Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" 0.1 1.4 0.8 0.1 0.5 0.2 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 1.5 0.0 0.2 0.0 0.0 1.1 1.6 0.0 0.0 0.2 1.4 0.0 0.8 0.2 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.1 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.8 0.7 1.5 1.1 1.6 0.8 1.3 1.9 0.8 4.2 0.0 3.6 0.0 0.0 0.0 1.1 0.0 0.0 4.2 0.0 0.0 0.6 0.0 0.6 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.1 0.3 0.1 0.3 17.6 0.0 1.4 0.0 0.0 1.0 0.0 0.3 1.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.3 0.0 0.0 0.1 0.2 1.0 42.7 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.1 11.7 0.4 0.0 3.1 0.2 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 1.2 SALL3 ZNF796 ENSG00000256463 "Spalt like transcription factor 3" Q9BXA9 18 78980275-79002677 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;prostate: 6.0;vagina: 8.0" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Bipolar cells: 14.7;Cone photoreceptor cells: 47.9;Horizontal cells: 25.2;Oligodendrocyte precursor cells: 21.1" "Cancer enriched" "Detected in some" 6 "glioma: 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;HEK 293: 2.7;NTERA-2: 9.5;SuSa: 1.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.5" "Low region specificity" "Detected in many" HPA016656 Uncertain NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "HPA016656: AB_1856546" "unprognostic (3.96e-2)" "unprognostic (3.41e-3)" "unprognostic (8.16e-2)" "unprognostic (1.87e-2)" "unprognostic (2.37e-1)" "unprognostic (4.23e-1)" "unprognostic (2.12e-1)" "unprognostic (1.11e-1)" "unprognostic (3.22e-1)" "unprognostic (5.86e-3)" 0.0 0.0 5.7 0.0 6.2 0.0 0.0 5.8 5.7 1.0 3.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 5.2 8.2 3.3 0.0 0.0 0.0 9.0 6.5 0.0 0.0 0.0 1.2 0.0 7.2 6.0 0.0 1.8 0.7 0.1 0.0 0.0 0.0 0.0 9.4 0.0 0.0 1.3 6.3 0.0 0.0 0.0 0.0 0.4 8.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 6.2 5.8 5.7 5.2 8.2 9.0 6.5 7.2 9.4 6.3 7.5 0.2 0.0 0.0 25.5 0.0 0.0 7.4 0.0 0.0 14.7 0.0 0.1 1.8 0.0 0.0 1.8 47.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 25.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 4.8 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 1.8 6.6 0.0 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 6.3 ATP9B ATPIIB ENSG00000166377 "ATPase phospholipid transporting 9B (putative)" O43861 18 79069285-79378287 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 128.2;Alveolar cells type 2: 156.2;Excitatory neurons: 126.0;Inhibitory neurons: 115.0;Oligodendrocyte precursor cells: 114.6;Oligodendrocytes: 157.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029364 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA029364: AB_10602595" "unprognostic (2.84e-3)" "unprognostic (1.66e-1)" "unprognostic (1.88e-1)" "unprognostic (6.51e-3)" "unprognostic (7.32e-2)" "unprognostic (7.66e-4)" "unprognostic (2.45e-2)" "unprognostic (7.43e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (1.92e-3)" "unprognostic (1.40e-1)" "unprognostic (1.84e-1)" "unprognostic (2.05e-2)" "unprognostic (1.09e-2)" 8.7 8.1 11.3 8.4 17.7 30.6 9.1 31.9 24.9 8.3 10.9 8.6 6.2 11.1 9.9 9.7 9.2 8.5 7.2 15.2 9.6 10.9 16.2 10.3 9.3 6.0 3.7 14.1 9.2 15.2 4.8 9.6 7.5 10.8 9.7 22.6 10.3 8.1 10.4 11.8 7.6 8.0 2.6 8.8 10.3 19.1 6.6 9.3 12.4 5.8 7.2 7.6 5.5 35.1 25.0 11.7 15.9 17.5 7.9 13.4 12.3 12.1 7.9 6.9 5.8 12.3 15.9 12.5 20.4 8.7 6.5 10.1 13.0 6.7 11.2 19.6 5.6 14.8 13.7 9.0 10.6 27.1 15.1 10.7 8.3 11.1 6.9 10.3 9.7 15.0 14.3 31.7 9.7 20.0 17.5 10.5 23.3 14.5 14.1 16.8 13.2 17.3 9.7 19.6 11.7 12.5 13.3 14.6 8.4 27.2 16.8 15.9 17.4 14.6 24.2 6.6 8.0 16.0 27.5 27.8 8.7 17.6 15.5 11.7 8.7 7.1 6.0 7.5 6.9 6.6 6.7 5.9 6.3 7.0 8.5 6.5 9.8 6.8 13.6 6.0 6.0 5.7 11.3 17.7 31.9 24.9 15.2 9.6 6.0 3.7 7.5 2.6 6.6 35.1 14.3 128.2 156.2 91.1 19.6 5.7 8.5 5.4 14.8 35.7 9.6 8.8 10.1 14.3 55.6 9.2 41.7 7.0 20.6 8.4 1.9 6.1 26.7 8.4 20.5 17.6 12.0 5.5 126.0 5.6 3.9 19.2 30.1 11.8 43.6 21.5 11.4 7.7 14.1 42.1 115.0 8.6 2.0 15.7 9.9 45.3 15.8 25.7 7.2 85.3 11.4 13.2 14.4 114.6 157.2 7.9 10.2 11.3 20.3 6.1 5.9 4.0 95.6 38.1 6.6 17.8 13.0 40.1 25.0 9.3 7.2 7.7 27.3 18.0 10.1 8.0 NFATC1 "NF-ATC, NFAT2, NFATc" ENSG00000131196 "Nuclear factor of activated T cells 1" O95644 18 79395856-79529325 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 50.4;Skeletal myocytes: 52.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 60.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004513, HPA071732" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nuclear bodies" Nucleoplasm "CAB004513: AB_628011, HPA071732: AB_2686439" "unprognostic (3.53e-2)" "unprognostic (2.16e-3)" "unprognostic (3.08e-3)" "unprognostic (3.40e-2)" "unprognostic (4.54e-2)" "unprognostic (2.79e-2)" "unprognostic (1.92e-1)" "unprognostic (4.85e-3)" "unprognostic (7.02e-2)" "unprognostic (8.37e-2)" "unprognostic (1.90e-2)" "unprognostic (1.38e-1)" "unprognostic (5.87e-2)" "unprognostic (1.38e-1)" "unprognostic (4.54e-2)" "unprognostic (5.04e-2)" "unprognostic (3.11e-3)" 12.8 4.6 4.8 11.7 6.0 3.9 10.6 5.6 4.1 6.0 27.9 10.1 3.0 7.7 0.9 3.0 8.0 10.0 15.5 4.3 5.4 4.8 2.7 13.6 21.2 8.3 7.2 7.2 7.0 4.1 3.4 4.1 6.4 6.4 1.5 0.5 6.4 2.9 32.7 10.6 13.2 3.2 7.5 18.7 5.4 8.5 7.2 8.3 7.7 9.3 13.5 7.1 6.1 6.4 0.0 4.0 1.9 3.6 3.3 3.6 6.9 2.4 0.3 0.6 0.3 0.3 3.6 22.0 1.5 3.2 5.6 0.4 9.9 0.0 0.8 15.3 8.0 15.4 0.9 0.1 7.3 4.9 8.2 4.3 0.0 1.2 0.1 0.0 12.2 9.0 12.5 4.5 2.4 8.4 12.8 1.7 3.5 2.9 2.6 4.0 2.5 5.0 1.8 1.6 0.0 0.0 3.2 2.6 5.6 4.2 3.2 19.7 11.4 5.0 20.9 0.0 0.3 0.1 0.1 60.2 0.0 6.6 9.3 1.8 3.4 7.5 4.0 9.1 4.2 7.6 6.2 5.5 3.1 10.0 5.2 3.7 2.9 2.1 13.6 3.0 5.0 4.7 4.8 6.0 5.6 4.1 4.3 5.4 8.3 7.2 6.4 7.5 7.2 6.4 19.4 0.0 6.0 13.4 50.4 37.2 30.0 7.0 6.2 0.1 19.2 13.5 8.4 5.7 8.1 0.0 0.0 0.3 11.8 0.1 0.0 5.7 12.1 10.6 5.4 25.2 0.0 5.9 0.2 4.0 7.2 24.3 8.6 16.1 31.8 1.2 39.3 0.6 12.3 0.0 0.2 0.0 2.0 12.6 35.4 20.3 8.4 21.9 10.6 9.4 6.9 2.5 13.4 4.0 1.3 4.9 0.0 9.8 8.9 12.0 0.0 0.5 4.4 0.1 0.0 52.1 14.2 11.4 13.2 1.5 29.7 0.5 29.4 2.1 0.1 7.7 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 KCNG2 "KCNF2, Kv6.2" ENSG00000178342 "Potassium voltage-gated channel modifier subfamily G member 2" Q9UJ96 18 79863668-79900184 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.2;Horizontal cells: 114.4;Inhibitory neurons: 31.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 5 "hippocampal formation: 10.3" HPA048628 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA048628: AB_2680466" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-1)" "unprognostic (1.99e-1)" "unprognostic (9.69e-2)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.40e-1)" "unprognostic (3.78e-1)" "unprognostic (3.61e-3)" "unprognostic (1.09e-1)" "unprognostic (3.18e-5)" "unprognostic (1.05e-1)" "unprognostic (7.72e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" 0.1 0.0 0.9 0.0 1.2 0.0 0.0 0.0 2.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.7 0.3 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.2 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.0 2.7 3.2 1.7 0.1 1.5 0.1 0.8 0.6 0.5 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.5 0.0 0.0 0.0 0.0 6.9 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 19.2 0.0 8.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 114.4 31.3 0.1 0.0 1.5 0.0 0.0 0.3 0.8 0.0 6.5 0.0 0.0 0.0 2.0 0.9 0.0 0.0 0.0 0.1 0.0 1.2 0.6 0.0 0.9 0.0 0.0 0.0 1.2 2.1 0.0 0.0 6.3 0.0 0.1 0.2 0.0 SLC66A2 "FLJ22378, PQLC1" ENSG00000122490 "Solute carrier family 66 member 2" Q8N2U9 18 79902420-79951657 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 185.4" "Cell type enhanced" "Detected in some" "Adipocytes: 20.3;Cardiomyocytes: 10.8;Cytotrophoblasts: 14.3;dendritic cells: 9.6;Extravillous trophoblasts: 14.6;Hofbauer cells: 36.1;Syncytiotrophoblasts: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051666 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA051666: AB_2681567" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-1)" "unprognostic (6.45e-2)" "unprognostic (3.94e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" "unprognostic (4.34e-1)" "unprognostic (1.40e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" "unprognostic (1.70e-2)" 57.1 24.4 32.1 14.4 30.4 38.3 53.4 25.3 40.0 30.3 33.5 38.0 9.7 27.4 5.6 46.5 27.0 14.5 32.4 37.0 26.9 49.0 185.4 37.4 18.1 34.5 31.2 21.6 33.8 11.5 23.8 10.3 31.9 32.2 7.5 7.2 38.9 9.9 83.9 55.5 24.5 8.5 29.1 34.4 25.6 77.0 34.3 12.3 68.4 25.9 8.9 26.3 34.2 29.2 34.8 11.7 11.9 23.0 26.0 16.6 16.0 22.4 15.1 17.6 16.6 15.6 18.5 14.6 8.5 20.4 10.3 34.8 16.2 23.8 4.7 44.3 23.8 18.2 16.7 42.6 30.9 44.2 44.5 18.6 23.2 16.2 6.2 9.0 15.3 15.8 6.9 11.6 9.2 26.6 22.1 47.6 3.9 4.7 31.5 38.7 12.4 24.6 12.0 24.4 34.8 15.7 16.9 21.3 25.6 3.1 12.7 48.0 19.4 26.8 27.2 14.3 17.2 5.8 10.0 18.8 20.5 53.2 12.1 0.3 1.7 2.0 0.6 1.7 0.4 0.8 0.7 0.3 1.9 0.6 0.9 1.1 1.2 1.0 1.6 3.5 0.8 0.8 32.1 30.4 25.3 40.0 37.0 26.9 34.5 31.2 31.9 29.1 34.3 29.2 20.3 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 14.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 14.6 4.6 0.0 0.0 0.0 0.0 0.0 0.0 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 20.8 2.0 0.0 0.0 0.0 HSBP1L1 "FLJ10967, MGC189743" ENSG00000226742 "Heat shock factor binding protein 1 like 1" C9JCN9 18 79964582-79970822 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 31.9;T-cells: 26.0" "Cell line enhanced" "Detected in many" "HHSteC: 162.8;SK-MEL-30: 100.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048273 Approved Approved Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA048273: AB_2680337" "unprognostic (2.08e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (8.15e-3)" "unprognostic (8.86e-2)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.53e-3)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.76e-2)" 9.6 17.4 18.4 2.9 17.8 2.9 9.6 19.9 26.4 10.0 23.4 16.0 6.7 7.6 11.1 17.4 8.7 5.7 6.7 17.2 18.1 18.6 29.7 10.7 4.2 19.1 18.5 6.6 20.4 19.7 6.7 9.9 19.6 10.2 13.1 14.8 12.8 7.6 12.5 16.0 6.5 5.7 18.1 5.2 10.1 0.8 20.3 4.3 8.9 10.6 4.9 6.2 10.6 17.2 32.2 8.6 0.3 0.5 4.6 15.4 12.7 14.3 32.2 14.8 13.0 16.5 21.7 0.0 3.6 18.8 0.2 18.3 28.5 18.9 7.0 30.6 6.7 0.0 8.8 9.6 162.8 0.0 0.0 18.0 49.6 1.7 10.8 31.5 0.3 4.8 0.0 0.0 0.7 26.8 0.1 0.0 0.0 17.6 30.1 0.3 0.0 0.0 53.7 7.6 0.5 1.8 15.2 20.9 100.2 1.4 11.9 7.6 0.0 0.1 0.0 0.4 0.1 0.0 16.7 0.0 0.2 8.9 0.6 31.9 6.8 8.6 5.8 4.4 6.9 2.2 10.1 6.2 2.8 2.5 26.0 14.0 0.4 5.2 1.6 3.3 4.9 6.2 18.4 17.8 19.9 26.4 17.2 18.1 19.1 18.5 19.6 18.1 20.3 17.2 36.4 54.5 34.5 12.1 5.0 39.8 66.0 135.5 67.2 12.0 89.8 93.6 12.4 48.6 109.2 49.7 22.9 126.6 9.6 119.8 68.4 63.8 1.3 47.2 13.2 23.0 11.5 11.4 5.7 62.1 67.1 16.0 31.6 59.4 19.0 37.2 30.0 122.5 44.7 20.2 11.0 81.3 71.2 20.5 18.0 1.3 19.9 16.0 39.2 6.5 4.0 33.2 6.2 1.0 3.1 137.3 99.6 24.5 2.3 80.2 70.6 80.6 80.3 33.0 0.0 6.3 15.9 1.3 1.3 46.8 57.8 117.4 12.2 34.5 99.6 104.4 TXNL4A "DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD" ENSG00000141759 "Thioredoxin like 4A" P83876 18 79970813-80033949 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, mRNA splicing" Deafness "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 360.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041324 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear membrane" Cytosol "HPA041324: AB_2677410" "unprognostic (7.56e-2)" "unprognostic (1.06e-3)" "unprognostic (5.94e-2)" "unprognostic (2.67e-2)" "unprognostic (6.99e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.38e-4)" "unprognostic (1.45e-1)" "unprognostic (9.39e-2)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (4.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" 61.1 79.1 88.1 39.9 92.5 59.6 52.1 96.0 98.7 37.2 94.9 53.5 32.8 35.7 50.3 69.4 38.1 24.1 88.6 95.0 98.4 87.7 97.1 48.2 53.4 89.4 95.8 32.6 86.0 42.2 95.5 31.6 94.1 53.9 33.2 36.5 55.0 25.3 88.5 59.3 48.0 25.6 93.1 67.8 60.5 88.0 91.6 52.4 51.1 61.3 45.6 46.1 45.5 99.3 98.5 129.3 113.0 108.1 90.3 94.7 99.8 104.3 83.5 138.7 124.9 121.2 68.0 118.8 37.8 100.3 94.1 81.4 137.1 121.5 91.2 139.7 173.7 85.6 196.1 288.7 115.4 247.6 134.1 88.6 105.5 98.7 125.6 87.9 132.4 145.0 76.2 168.0 97.8 177.1 177.0 166.3 88.6 74.3 276.9 106.2 75.7 245.4 137.7 152.7 172.1 125.0 51.6 151.8 200.5 96.9 74.6 145.0 62.9 121.3 149.5 55.7 129.4 74.0 302.3 198.6 113.4 185.7 113.9 10.6 10.3 9.0 14.7 12.7 9.9 15.8 11.8 11.6 14.5 17.6 11.7 14.0 8.2 15.6 13.1 31.3 17.3 6.1 88.1 92.5 96.0 98.7 95.0 98.4 89.4 95.8 94.1 93.1 91.6 99.3 81.0 19.2 42.6 14.0 89.2 87.2 76.9 73.6 64.3 35.7 131.9 139.7 80.3 65.8 62.3 66.2 35.5 107.8 104.8 53.6 360.0 123.4 259.3 98.5 66.0 65.2 56.3 94.1 25.3 125.2 156.9 69.8 71.4 88.1 11.4 84.1 47.2 97.4 126.0 45.4 22.5 88.4 59.0 66.4 76.9 245.5 42.0 89.5 94.3 14.0 87.2 81.5 60.8 21.1 34.8 144.5 54.9 45.1 177.9 177.2 48.6 271.8 41.9 51.3 46.0 61.2 100.8 84.6 74.2 147.6 109.8 96.7 78.7 112.6 71.1 119.4 RBFA "C18orf22, FLJ21172, HsT169" ENSG00000101546 "Ribosome binding factor A" Q8N0V3 18 80034389-80050651 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040485, HPA041479" Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA040485: AB_10795368, HPA041479: AB_10795697" "unprognostic (5.31e-3)" "unprognostic (3.21e-2)" "unprognostic (1.87e-1)" "unprognostic (4.55e-2)" "unprognostic (7.33e-2)" "unprognostic (5.00e-3)" "prognostic unfavorable (2.06e-6)" "unprognostic (2.98e-1)" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (4.28e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (3.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.82e-1)" "unprognostic (5.00e-3)" 18.6 19.9 6.2 9.8 6.1 13.6 17.8 8.1 6.6 13.6 4.7 13.6 12.0 12.4 5.5 17.6 11.0 5.9 18.3 6.3 6.3 14.8 31.3 10.6 8.5 5.8 5.4 10.1 16.7 9.1 8.9 8.3 5.8 11.6 7.9 5.9 12.7 6.8 22.3 20.0 10.9 10.0 5.4 12.4 11.9 12.1 5.8 10.3 11.0 13.3 10.7 13.4 14.2 6.4 28.4 32.6 20.5 20.0 17.5 20.2 27.7 24.0 11.9 25.8 21.9 19.1 22.1 58.6 8.9 16.5 22.6 26.1 21.8 26.1 20.5 22.1 23.9 35.3 24.6 53.0 14.6 55.7 16.7 18.8 24.9 18.6 26.3 11.3 22.4 35.3 19.1 35.7 15.5 30.0 55.6 38.4 22.4 17.7 30.6 38.0 19.6 72.5 26.8 35.2 35.7 21.3 21.0 23.4 17.3 17.0 17.7 29.5 19.7 37.6 37.2 5.5 27.0 14.1 24.5 48.7 22.1 46.2 22.4 0.0 4.8 0.0 6.4 6.5 10.1 8.9 6.5 6.4 7.6 6.5 7.4 6.8 0.2 7.3 10.3 5.7 5.5 5.3 6.2 6.1 8.1 6.6 6.3 6.3 5.8 5.4 5.8 5.4 5.8 6.4 25.4 32.1 10.9 14.0 24.1 18.5 24.4 29.8 25.6 13.5 29.2 32.5 12.2 18.6 24.4 27.6 18.8 50.1 14.8 9.9 31.3 28.4 17.7 23.7 39.0 20.3 20.9 29.9 18.3 24.2 49.9 24.7 19.4 20.9 13.3 34.5 15.7 40.8 24.4 32.0 17.5 21.7 14.2 8.2 20.5 17.0 19.0 15.2 33.8 12.2 9.6 8.0 19.6 19.6 14.1 21.3 7.6 18.4 26.2 23.8 13.7 46.4 19.4 21.8 19.7 17.3 26.3 37.7 49.2 38.2 23.4 24.9 16.7 47.5 25.5 20.9 ADNP2 "KIAA0863, ZNF508" ENSG00000101544 "ADNP homeobox 2" Q6IQ32 18 80109262-80147523 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007126 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Mitochondria, Cytosol" "HPA007126: AB_1080729" "unprognostic (4.93e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-2)" "unprognostic (2.25e-1)" "unprognostic (1.25e-1)" "unprognostic (1.69e-1)" "unprognostic (3.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.24e-1)" "unprognostic (6.05e-2)" "unprognostic (3.40e-2)" "unprognostic (8.35e-2)" "prognostic favorable (6.39e-5)" "unprognostic (8.64e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (9.90e-4)" "unprognostic (5.19e-2)" 8.0 6.2 17.3 6.6 13.1 41.3 8.1 7.3 31.2 6.0 9.9 7.2 9.1 7.4 10.8 8.6 6.6 7.5 8.0 10.2 9.1 6.7 7.9 7.5 7.2 15.4 10.1 8.0 8.2 9.6 6.9 6.7 14.0 6.8 6.6 12.4 6.4 6.3 2.7 12.7 6.6 7.8 9.4 6.5 7.8 22.0 18.0 9.4 8.4 4.5 7.1 7.7 6.9 15.6 23.1 17.8 36.2 27.0 8.1 11.4 27.0 16.3 18.6 19.2 23.8 16.9 11.5 0.2 6.2 13.3 23.6 20.8 35.4 21.1 20.2 21.0 17.8 32.3 12.8 18.5 14.8 47.5 34.5 11.9 19.6 19.7 26.1 12.8 19.4 36.1 31.8 33.3 11.4 16.4 43.8 9.9 24.9 10.3 20.6 16.6 40.5 16.4 11.6 30.3 24.7 31.8 18.4 18.1 13.0 17.6 17.8 36.0 13.3 22.6 56.6 9.5 18.4 11.7 23.1 46.8 15.1 19.8 15.7 0.0 0.4 0.2 1.2 0.7 0.8 0.8 1.5 1.0 0.2 0.3 0.8 1.4 0.6 0.6 1.2 0.8 0.8 0.5 17.3 13.1 7.3 31.2 10.2 9.1 15.4 10.1 14.0 9.4 18.0 15.6 17.0 19.2 20.9 21.9 10.2 39.5 24.4 11.7 16.5 20.3 17.0 11.9 16.6 10.0 12.6 3.7 27.1 10.1 15.5 17.4 0.0 7.9 9.9 15.8 14.2 14.5 22.2 22.3 22.7 10.9 8.3 15.9 13.3 31.2 12.0 13.6 15.4 19.5 9.9 25.2 25.2 18.9 14.2 10.6 13.8 8.2 7.5 14.6 14.2 11.2 5.5 9.7 3.1 17.1 36.8 11.5 15.9 11.7 9.7 21.7 10.6 7.2 10.2 30.2 0.0 15.6 14.5 45.4 38.3 23.7 43.2 9.7 15.5 17.8 13.6 32.2 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4