Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" FAM110C ENSG00000184731 "Family with sequence similarity 110 member C" Q1W6H9 2 38814-46870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 32.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 248.8;Basal squamous epithelial cells: 90.0;Endometrial ciliated cells: 85.6;Glandular and luminal cells: 158.2;Urothelial cells: 236.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 13.3;HBEC3-KT: 10.3;hTCEpi: 10.1;RPTEC TERT1: 17.3;RT4: 24.5;SK-BR-3: 10.9" "Region enriched" "Detected in single" 6 "olfactory bulb: 1.9" "Low region specificity" "Detected in some" "HPA036144, HPA036145" Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA036144: AB_10670710, HPA036145: AB_2674968" "unprognostic (4.29e-2)" "unprognostic (1.96e-1)" "unprognostic (8.47e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.07e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (3.94e-1)" "unprognostic (1.73e-1)" "unprognostic (8.36e-2)" "unprognostic (1.90e-1)" "unprognostic (5.02e-2)" "unprognostic (3.64e-2)" "unprognostic (1.41e-2)" "unprognostic (4.82e-3)" "unprognostic (2.68e-1)" 11.1 3.4 2.0 1.8 3.2 0.1 5.3 0.0 2.5 8.7 3.3 8.4 10.9 3.9 20.7 32.8 8.7 8.4 3.2 2.5 0.5 16.5 17.5 3.3 0.2 1.1 0.5 6.5 14.3 5.3 4.0 0.2 0.7 4.2 10.1 1.1 5.8 19.8 0.1 9.9 9.6 1.8 0.6 0.3 7.5 3.6 1.2 1.9 5.8 0.3 2.2 11.1 15.4 1.7 5.2 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 8.3 0.0 6.3 0.0 0.3 13.3 0.0 10.3 0.0 0.8 0.4 0.0 1.8 1.1 0.0 0.0 0.0 0.0 10.1 0.0 1.7 0.0 0.0 9.1 0.0 0.0 0.0 9.0 6.0 0.1 1.2 6.1 3.2 0.0 0.0 0.0 17.3 24.5 0.6 0.0 0.0 10.9 0.0 1.0 3.8 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 2.0 3.2 0.0 2.5 2.5 0.5 1.1 0.5 0.7 0.6 1.2 1.7 0.1 0.0 5.8 2.3 0.2 22.9 248.8 12.1 90.0 0.1 9.5 4.7 5.8 27.1 17.4 35.0 0.0 0.0 0.7 40.1 19.6 13.5 0.2 85.6 14.2 1.6 29.8 0.0 2.7 5.3 0.0 4.4 10.2 158.2 0.0 57.3 0.7 13.4 0.1 3.3 0.7 35.8 6.1 0.3 0.7 0.9 2.1 1.6 0.0 0.0 0.0 2.2 1.0 0.0 0.3 9.0 38.6 1.9 1.4 23.1 14.6 13.3 4.3 0.1 0.0 0.1 3.4 0.5 0.2 71.8 30.1 0.0 2.6 0.1 11.1 236.0 SH3YL1 "DKFZP586F1318, Ray" ENSG00000035115 "SH3 and SYLF domain containing 1" Q96HL8 2 217730-266398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 606.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 223.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030926, HPA030927" Enhanced Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA030926: AB_10670148, HPA030927: AB_10669874" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (5.10e-2)" "unprognostic (2.28e-3)" "unprognostic (5.06e-3)" "unprognostic (1.82e-1)" "unprognostic (1.46e-1)" "unprognostic (6.57e-3)" "unprognostic (9.25e-2)" "unprognostic (6.40e-2)" "unprognostic (1.71e-2)" "unprognostic (2.81e-1)" "prognostic favorable (7.70e-4)" "unprognostic (1.95e-3)" "unprognostic (1.10e-1)" "unprognostic (1.47e-1)" "unprognostic (3.22e-3)" 13.6 32.0 26.6 11.9 27.7 11.6 54.8 27.5 37.2 31.8 28.3 45.6 35.1 27.0 40.8 43.8 43.6 45.2 11.0 26.8 25.5 145.6 11.6 35.7 22.1 27.4 26.8 28.6 161.6 55.7 33.9 26.9 27.8 34.4 53.2 10.7 114.0 24.3 13.4 75.0 51.7 11.9 26.4 16.0 72.3 17.0 27.9 15.4 59.2 8.3 28.0 49.3 27.1 33.1 12.7 2.4 13.5 6.0 18.1 16.8 9.0 15.7 17.4 5.8 6.0 33.6 46.3 0.6 7.3 13.8 3.9 51.6 3.4 67.6 5.4 10.2 2.4 3.0 3.9 10.9 14.5 1.5 3.8 18.6 68.2 3.5 11.0 28.7 8.7 17.2 0.9 2.3 12.0 37.1 13.4 6.9 4.4 223.4 2.6 6.4 4.1 0.9 41.4 69.8 5.5 9.1 2.6 64.1 11.9 17.5 44.0 10.6 6.6 2.9 0.8 16.9 6.9 1.7 0.1 1.2 28.8 20.7 9.8 38.9 2.5 1.9 4.5 3.1 14.3 12.6 22.4 11.5 6.1 10.1 33.9 20.5 1.5 22.9 4.9 5.5 30.6 8.2 26.6 27.7 27.5 37.2 26.8 25.5 27.4 26.8 27.8 26.4 27.9 33.1 14.8 57.7 116.7 51.2 29.7 82.7 173.5 174.4 42.7 19.3 140.2 130.3 6.6 313.1 139.7 101.2 22.9 197.7 15.8 84.5 291.6 129.2 136.6 148.5 32.3 15.9 49.1 3.8 62.3 143.9 69.9 22.6 31.1 216.6 15.8 51.9 19.2 7.9 26.5 26.9 57.1 97.4 109.9 9.5 17.0 113.1 36.7 14.9 72.9 23.4 15.2 9.4 30.9 44.2 87.2 104.6 115.3 41.0 4.7 166.3 125.1 606.2 85.2 9.7 26.3 20.4 20.5 63.3 23.2 29.5 115.4 247.0 35.7 37.1 123.8 245.3 ACP1 "HAAP, LMW-PTP, LMWPTP" ENSG00000143727 "Acid phosphatase 1" P24666 2 264140-278283 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 1061.1;Late spermatids: 2128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016754 Approved Approved Nucleoplasm,Cytosol NA NA 2000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Cytosol "HPA016754: AB_1844505" "unprognostic (1.15e-1)" "unprognostic (1.36e-1)" "unprognostic (1.37e-2)" "unprognostic (6.25e-3)" "unprognostic (1.06e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (6.67e-6)" "unprognostic (2.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (9.72e-3)" "unprognostic (4.89e-2)" "unprognostic (2.71e-2)" "unprognostic (7.10e-2)" "unprognostic (2.88e-2)" "unprognostic (3.39e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" 41.2 104.0 43.1 45.5 47.6 91.9 64.7 43.9 54.0 43.4 63.9 61.4 64.0 46.6 69.3 43.3 57.9 45.4 57.3 49.4 47.1 78.1 106.4 46.8 66.2 43.4 44.2 59.2 94.1 73.9 59.2 61.7 44.3 52.1 64.7 72.7 71.1 44.2 76.6 41.3 60.7 41.5 44.9 44.7 67.1 46.1 45.3 66.2 63.7 74.9 61.9 47.5 36.4 50.2 78.3 112.5 177.4 97.4 76.1 77.1 142.2 92.6 97.7 91.9 80.8 151.7 78.5 48.8 70.7 85.1 114.6 76.5 169.4 97.0 82.3 118.7 157.9 142.3 99.0 348.5 105.7 162.5 80.4 78.7 90.5 81.9 102.3 95.5 105.8 176.9 145.1 95.1 110.9 103.1 178.5 161.3 214.1 204.7 111.7 118.2 176.1 114.5 144.2 110.5 191.6 191.3 56.0 137.6 196.3 115.0 82.1 89.8 88.9 101.3 65.2 84.0 142.6 123.8 261.2 150.4 120.0 138.9 123.7 65.4 61.6 57.2 88.8 75.2 118.1 106.6 100.4 103.2 57.3 97.2 118.1 115.2 10.9 121.5 80.2 65.3 117.6 115.0 43.1 47.6 43.9 54.0 49.4 47.1 43.4 44.2 44.3 44.9 45.3 50.2 62.5 44.8 96.7 9.1 102.6 79.2 105.3 173.4 51.8 53.1 118.8 130.0 84.9 131.5 119.6 68.0 8.4 207.1 101.3 81.9 270.1 226.7 1061.1 113.1 56.2 70.6 82.5 291.5 20.4 169.0 279.7 74.2 54.6 85.5 70.3 95.9 56.0 115.8 141.1 28.6 21.0 125.1 126.1 72.0 66.3 2128.2 94.4 74.6 81.8 16.9 117.8 92.2 152.4 19.6 26.0 174.4 109.2 92.2 106.4 187.0 174.2 306.6 128.1 56.9 92.1 42.5 87.0 122.6 137.4 87.4 91.2 187.7 86.0 124.4 143.9 148.3 ALKAL2 "AUGA, FAM150B" ENSG00000189292 "ALK and LTK ligand 2" Q6UX46 2 279558-288851 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 205.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 20.3;Ductal cells: 37.0;Endometrial ciliated cells: 24.0;Glandular and luminal cells: 50.3;Granulosa cells: 64.3;Proximal tubular cells: 28.1" "Cancer enhanced" "Detected in many" "renal cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "AF22: 138.8" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 4.3;basal ganglia: 3.0;cerebral cortex: 2.5;hippocampal formation: 3.4;spinal cord: 2.3" "Secreted - unknown location" NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.39e-3)" "unprognostic (1.44e-2)" "unprognostic (2.41e-2)" "unprognostic (2.03e-3)" "unprognostic (2.88e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.35e-1)" "unprognostic (9.29e-3)" "unprognostic (5.19e-2)" "unprognostic (3.68e-1)" 28.8 205.4 4.6 2.0 6.3 0.6 26.6 3.5 2.9 4.9 4.8 8.2 3.7 26.4 13.4 2.0 26.2 10.7 2.2 3.1 5.4 21.1 4.5 34.0 0.9 3.6 2.1 74.4 64.3 2.3 8.6 9.6 2.7 6.5 6.5 0.4 5.4 2.6 1.5 17.3 7.7 9.9 1.8 12.3 17.3 35.5 5.1 1.7 10.4 0.5 1.6 4.7 5.3 4.8 0.0 0.0 138.8 0.1 0.8 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.0 0.4 1.3 0.0 0.0 0.2 0.5 0.0 0.0 0.5 0.3 0.0 0.1 0.7 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.2 2.4 0.0 0.0 6.8 0.4 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.1 0.1 0.2 0.2 0.3 0.7 0.1 0.3 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.1 4.6 6.3 3.5 2.9 3.1 5.4 3.6 2.1 2.7 1.8 5.1 4.8 2.5 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 14.6 20.3 0.0 0.0 0.0 1.8 0.0 0.1 1.4 0.0 3.9 37.0 0.0 24.0 6.3 4.5 0.0 0.0 0.0 0.7 0.1 3.1 0.0 50.3 0.0 64.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.6 0.9 0.0 0.0 TMEM18 "DKFZp434C1714, lncND" ENSG00000151353 "Transmembrane protein 18" Q96B42 2 663877-677406 "Predicted membrane proteins, Transporters" Transcription DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040233 Approved Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Endoplasmic reticulum" "HPA040233: AB_10794737" "unprognostic (9.01e-3)" "unprognostic (2.45e-1)" "unprognostic (7.48e-2)" "unprognostic (1.77e-3)" "unprognostic (2.68e-2)" "unprognostic (1.61e-1)" "unprognostic (1.27e-2)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (6.05e-2)" "unprognostic (1.86e-1)" "unprognostic (9.45e-2)" "unprognostic (8.20e-2)" "unprognostic (2.49e-1)" "unprognostic (3.65e-1)" "unprognostic (4.98e-3)" "unprognostic (8.08e-2)" 18.5 19.9 9.3 6.3 9.1 8.8 18.5 8.8 11.7 14.8 7.6 12.3 8.9 17.7 9.7 14.8 15.8 8.5 11.6 9.6 10.0 13.2 10.1 11.0 8.4 9.8 9.4 28.3 25.2 12.4 9.7 9.9 9.8 9.5 6.2 12.0 14.3 7.0 27.3 15.4 10.1 9.5 9.4 9.2 13.3 12.2 10.2 7.0 12.8 12.2 6.4 13.6 13.1 10.4 17.4 14.1 20.3 21.7 23.9 35.4 19.0 23.8 19.0 20.2 19.5 1.9 27.6 25.1 44.5 31.1 10.7 24.0 7.2 26.3 17.8 37.1 16.6 14.4 7.6 28.7 25.9 13.5 11.9 24.6 26.4 35.1 26.7 18.2 5.9 39.1 14.7 14.7 30.5 48.1 32.7 32.1 13.8 15.1 21.4 17.8 9.9 17.8 21.0 16.3 14.4 24.9 13.1 22.7 25.4 9.5 16.2 25.6 19.5 19.0 25.5 12.6 36.7 19.3 34.4 21.8 20.7 14.4 13.1 3.8 16.1 6.9 11.8 15.7 11.3 18.4 13.5 9.5 16.6 14.8 14.8 14.4 1.0 18.5 18.4 22.3 17.1 13.1 9.3 9.1 8.8 11.7 9.6 10.0 9.8 9.4 9.8 9.4 10.2 10.4 49.2 22.4 32.8 4.6 39.4 35.9 29.7 46.0 61.5 19.8 68.3 108.2 28.3 31.5 39.2 27.6 8.4 72.5 28.1 26.0 31.3 34.1 14.2 37.5 53.7 41.0 19.8 37.9 4.1 46.3 62.1 47.1 27.0 53.1 29.8 77.6 38.2 37.4 49.1 20.2 3.9 39.4 36.7 37.4 31.5 13.1 63.3 31.2 40.9 2.8 36.4 49.8 20.6 4.5 10.2 36.6 50.7 51.1 43.1 40.1 51.0 45.8 32.1 33.7 19.7 31.8 48.8 93.3 68.1 72.6 43.2 81.1 30.0 63.5 41.7 40.4 SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 68.2;Excitatory neurons: 24.4;Horizontal cells: 90.9;Late spermatids: 44.7;Spermatocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HAP1: 1.7;JURKAT: 1.6;MOLT-4: 1.1;NTERA-2: 2.0;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" 2.0 0.3 0.6 0.0 0.7 0.0 1.8 1.0 0.6 1.0 1.1 0.5 0.1 1.2 0.2 0.5 1.2 0.2 0.4 1.7 0.7 0.1 0.0 0.3 0.0 1.7 0.9 0.2 0.9 0.0 2.9 0.0 1.3 0.6 0.2 2.1 0.5 0.0 0.4 1.1 0.6 0.7 0.4 3.2 0.3 1.8 0.7 0.2 0.7 0.9 0.1 0.8 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.0 0.6 1.7 0.7 1.7 0.9 1.3 0.4 0.7 0.6 6.8 0.0 0.0 0.7 0.4 0.9 0.1 0.0 0.6 0.8 0.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.2 0.1 0.9 7.3 0.0 0.0 24.4 0.2 0.5 0.8 0.0 0.0 0.0 3.0 0.0 0.0 0.1 90.9 10.7 0.0 0.0 0.0 1.2 44.7 0.3 0.0 1.8 9.4 0.0 0.6 0.0 1.5 1.3 0.0 0.0 4.1 0.0 0.3 0.0 0.5 0.0 4.6 0.0 0.3 0.4 22.0 5.4 0.1 0.1 0.0 0.2 0.2 0.0 0.2 TPO TPX ENSG00000115705 "Thyroid peroxidase" P07202 2 1374066-1543711 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen peroxide, Thyroid hormones biosynthesis" "Oxidoreductase, Peroxidase" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 70 "thyroid gland: 1588.2" "Cell type enhanced" "Detected in some" "Adipocytes: 24.5;Early spermatids: 4.2;Endothelial cells: 12.6;Late spermatids: 7.5;Peritubular cells: 3.8" "Cancer enriched" "Detected in some" 364 "thyroid cancer: 188.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory CD4 T-cell: 2.0;T-reg: 1.2" "Lineage enriched" "Detected in single" 20 "T-cells: 2.0" "Group enriched" "Detected in some" 5 "Karpas-707: 9.9;RPMI-8226: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA007987, CAB009587" Enhanced "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB009587: , HPA007987: AB_1080270" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" "unprognostic (2.88e-1)" "unprognostic (1.77e-2)" "unprognostic (3.56e-2)" "unprognostic (9.11e-2)" "unprognostic (2.24e-2)" "unprognostic (1.85e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-4)" "unprognostic (2.61e-2)" "unprognostic (3.29e-1)" "unprognostic (5.44e-4)" "unprognostic (1.21e-1)" "unprognostic (3.73e-2)" "unprognostic (4.98e-3)" "unprognostic (7.10e-3)" 13.1 0.3 0.1 0.4 0.0 0.1 11.0 0.0 0.6 0.1 0.0 4.6 0.6 0.6 0.0 2.0 0.7 3.0 11.5 0.1 0.2 0.2 0.6 0.8 1.4 0.2 0.1 0.3 2.3 0.3 0.6 0.0 0.1 0.6 0.9 0.2 3.4 0.0 6.0 1.8 3.8 0.6 0.1 22.8 2.8 1.2 0.2 0.0 1588.2 5.6 0.4 2.1 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.9 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.2 0.1 0.0 0.0 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.4 24.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.2 0.0 0.2 12.6 0.0 0.0 2.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.6 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 1.1 3.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.8 0.3 0.5 0.1 0.0 0.0 0.2 0.1 0.0 0.1 PXDN "D2S448, D2S448E, KIAA0230, MG50, PRG2, PXN" ENSG00000130508 Peroxidasin Q92626 2 1631887-1744852 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 79.1;Endometrial stromal cells: 99.4;Endothelial cells: 95.1;Hepatic stellate cells: 71.4;Skeletal myocytes: 120.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 323.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA012375 Approved "Secreted to extracellular matrix" NA NA 9100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA012375: AB_1855965" "unprognostic (4.37e-2)" "prognostic unfavorable (6.28e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.75e-4)" "unprognostic (8.16e-3)" "unprognostic (1.91e-1)" "unprognostic (1.92e-2)" "unprognostic (3.15e-3)" "unprognostic (6.50e-3)" "unprognostic (1.34e-2)" "unprognostic (6.78e-2)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.18e-1)" "unprognostic (7.33e-3)" "unprognostic (5.54e-3)" 59.5 5.5 4.1 24.3 3.5 0.9 33.7 1.9 4.1 18.2 27.5 36.1 7.9 32.8 4.0 4.9 18.0 22.7 22.7 3.1 7.7 9.0 12.4 27.6 5.0 4.2 6.2 32.7 3.8 3.0 11.7 33.4 4.7 17.5 8.7 5.2 13.6 11.1 7.7 6.9 16.3 61.8 2.6 10.0 13.2 6.4 5.2 2.1 8.4 11.5 2.1 33.8 13.5 3.4 39.9 13.9 72.0 0.1 198.3 180.9 54.6 231.4 182.3 99.0 107.9 0.1 0.5 0.0 323.8 230.3 4.5 8.3 0.3 142.3 125.5 0.6 2.4 0.0 139.3 0.0 196.4 0.6 0.0 200.7 41.0 112.2 83.8 299.5 247.0 35.9 0.1 0.0 142.6 23.6 6.8 8.0 58.3 0.0 52.3 13.2 250.8 0.6 115.9 0.1 0.2 131.9 0.2 73.6 0.4 142.9 27.0 0.9 242.4 162.8 79.7 6.2 180.7 0.2 205.4 1.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 4.1 3.5 1.9 4.1 3.1 7.7 4.2 6.2 4.7 2.6 5.2 3.4 79.1 6.4 2.3 2.6 0.4 2.9 2.8 12.8 0.6 2.5 17.5 14.1 5.8 17.2 7.0 1.8 0.0 0.6 0.2 0.3 0.0 10.4 33.4 4.2 99.4 95.1 1.8 0.0 6.6 0.0 11.3 45.2 0.0 3.4 1.3 43.7 71.4 1.8 1.9 0.0 7.3 1.3 20.3 5.7 4.4 40.7 26.8 0.7 7.2 8.4 0.6 10.0 1.0 55.8 0.7 0.5 0.1 15.1 0.0 14.0 0.0 0.2 6.7 0.8 46.0 120.1 51.1 22.0 16.0 0.5 2.8 1.4 1.0 33.3 0.5 1.4 MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.8;pituitary gland: 14.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 582.4;Inhibitory neurons: 635.5;Oligodendrocyte precursor cells: 265.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 45.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 18.6;SH-SY5Y: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" 0.0 1.4 7.8 0.2 14.1 0.1 0.0 4.2 45.8 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 17.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 14.8 0.1 0.0 0.1 0.1 5.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 18.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 7.8 14.1 4.2 45.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.1 6.4 6.1 16.6 0.0 1.8 0.5 0.0 0.0 46.7 0.5 0.4 4.5 0.0 3.1 1.8 2.1 0.1 0.2 0.1 0.0 0.0 5.0 0.4 0.1 1.3 0.0 0.0 582.4 0.0 0.2 1.3 0.0 0.2 6.3 0.1 0.7 0.4 0.1 117.8 635.5 0.0 0.0 0.6 0.8 4.7 0.0 0.8 0.0 18.7 0.0 1.5 0.0 265.4 11.1 0.1 0.0 1.5 0.1 0.4 0.0 0.2 1.5 7.4 6.6 1.5 0.4 50.0 31.4 0.0 1.0 0.3 0.9 0.1 0.0 0.6 EIPR1 "EIPR-1, TSSC1" ENSG00000032389 "EARP complex and GARP complex interacting protein 1" Q53HC9 2 3188925-3377830 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 48.6;Distal tubular cells: 50.9;Ductal cells: 28.7;Extravillous trophoblasts: 36.9;Hofbauer cells: 34.0;Proximal tubular cells: 41.6;Syncytiotrophoblasts: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031231, HPA031232, HPA031233, HPA031234" Approved Supported "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Nucleoli" "Intermediate filaments" "HPA031231: AB_10669881, HPA031232: AB_10603222, HPA031233: AB_10670026, HPA031234: AB_2673803" "unprognostic (2.16e-1)" "unprognostic (2.22e-1)" "unprognostic (2.71e-1)" "unprognostic (1.66e-1)" "unprognostic (4.27e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (3.67e-7)" "unprognostic (1.94e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (2.10e-1)" "unprognostic (2.50e-1)" "unprognostic (1.78e-1)" "unprognostic (1.02e-2)" "unprognostic (3.43e-1)" "unprognostic (2.24e-2)" "unprognostic (3.83e-2)" 8.5 15.2 24.8 13.8 25.6 18.2 9.8 24.3 27.3 9.3 20.5 13.6 12.2 9.9 19.4 19.7 13.2 7.7 11.9 26.0 26.2 17.9 16.5 9.3 19.2 22.2 23.2 6.9 10.5 15.8 27.8 9.1 23.9 9.5 11.8 15.9 11.2 7.8 14.0 13.9 10.6 10.6 22.9 14.6 10.8 11.6 25.1 22.2 22.4 15.2 18.0 10.8 11.1 23.6 25.4 48.2 25.9 28.2 15.7 21.1 56.2 26.8 27.8 32.0 24.2 32.5 32.6 45.3 46.8 28.3 30.1 25.9 20.9 39.3 17.3 35.5 37.5 40.7 28.4 76.2 29.9 40.2 49.9 19.5 35.1 32.2 43.6 17.6 41.9 79.0 45.2 30.9 29.7 48.5 37.6 57.9 29.4 61.5 38.1 43.6 26.6 61.6 39.6 35.7 54.5 62.6 18.5 31.7 30.1 13.8 29.0 36.9 29.9 25.3 13.1 21.2 36.9 34.9 88.0 37.8 30.0 40.8 24.1 22.2 15.2 12.8 19.7 17.9 19.6 16.8 16.1 20.6 27.4 20.6 17.6 18.8 6.5 22.2 16.7 30.3 22.2 18.6 24.8 25.6 24.3 27.3 26.0 26.2 22.2 23.2 23.9 22.9 25.1 23.6 5.6 3.2 9.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 8.5 7.0 0.0 0.0 6.2 20.2 0.0 48.6 7.0 0.0 50.9 28.7 0.0 14.9 7.5 7.0 0.0 0.0 0.0 16.0 36.9 5.0 0.0 11.5 3.8 13.7 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 0.0 0.0 0.0 20.7 0.0 0.0 2.3 0.0 0.0 41.6 4.4 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 26.7 5.7 24.5 0.0 0.0 TRAPPC12 "CGI-87, TTC-15, TTC15" ENSG00000171853 "Trafficking protein particle complex 12" Q8WVT3 2 3379675-3485094 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 96.6" "Cell type enhanced" "Detected in all" "Early spermatids: 293.9;Late spermatids: 504.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034799, HPA043196" Uncertain Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "HPA034799: AB_10600920, HPA043196: " "prognostic favorable (1.80e-5)" "unprognostic (9.21e-2)" "unprognostic (1.01e-2)" "unprognostic (1.97e-2)" "unprognostic (7.96e-2)" "unprognostic (1.32e-2)" "unprognostic (1.57e-2)" "unprognostic (1.80e-2)" "unprognostic (1.38e-1)" "unprognostic (4.27e-1)" "prognostic favorable (9.15e-4)" "unprognostic (3.23e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.53e-1)" "unprognostic (7.18e-2)" 21.7 26.0 13.9 10.9 14.4 10.1 21.8 15.0 23.3 20.2 13.5 27.9 10.1 23.7 6.3 23.0 22.2 10.4 46.7 14.8 15.9 22.6 28.0 17.1 16.0 15.9 14.1 21.4 26.2 18.4 26.7 6.6 17.1 20.6 4.7 9.1 25.8 10.0 45.8 35.7 21.2 5.2 14.6 22.1 28.4 96.6 14.8 15.7 24.7 6.4 5.0 26.1 18.9 15.5 16.4 28.0 9.1 10.4 19.9 24.5 23.9 26.6 6.5 7.6 4.2 17.5 13.6 18.8 28.6 9.0 6.7 20.8 10.5 11.9 3.1 22.8 39.5 16.2 8.1 60.8 9.0 20.4 28.0 18.1 9.0 8.5 21.2 5.8 6.7 21.5 25.5 10.0 13.5 22.5 20.6 34.9 22.1 7.3 39.4 15.4 12.4 15.3 8.1 13.5 23.2 37.8 10.6 11.8 18.5 4.0 13.9 16.3 17.2 18.6 10.6 18.7 23.6 28.5 22.4 15.0 21.8 15.9 10.5 0.7 1.0 3.8 0.8 2.5 2.0 0.5 1.3 2.2 1.4 0.5 0.8 1.0 1.0 0.9 3.6 4.3 2.5 0.8 13.9 14.4 15.0 23.3 14.8 15.9 15.9 14.1 17.1 14.6 14.8 15.5 18.8 9.6 12.8 59.4 20.7 11.5 16.2 15.1 14.2 31.8 13.7 16.0 68.4 21.5 11.2 12.9 33.3 21.3 16.9 17.1 58.7 21.7 293.9 20.3 16.4 18.5 3.5 19.1 56.2 18.0 15.2 23.7 23.0 14.5 5.7 22.3 11.0 16.0 25.9 26.9 62.5 17.7 14.2 17.9 10.0 504.5 26.4 20.7 16.0 30.0 28.5 42.6 15.5 52.3 56.4 23.9 11.9 24.0 19.6 16.0 20.3 30.0 19.4 42.0 26.3 20.9 21.7 125.2 26.3 18.8 17.8 17.6 14.4 33.8 15.7 12.2 ADI1 "APL1, ARD, FLJ10913, HMFT1638, MTCBP-1, mtnD, SIPL" ENSG00000182551 "Acireductone dioxygenase 1" Q9BV57 2 3497366-3519531 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 590.7" "Cell type enhanced" "Detected in all" "Distal tubular cells: 888.3;Hepatocytes: 1234.6;Proximal tubular cells: 1546.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035403, HPA035404" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus" "HPA035403: AB_10603576, HPA035404: AB_2674611" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (4.23e-3)" "unprognostic (2.36e-3)" "unprognostic (4.00e-3)" "unprognostic (2.97e-2)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (9.94e-2)" "unprognostic (6.76e-2)" "unprognostic (8.74e-2)" 55.1 76.9 31.1 28.0 32.6 31.7 50.4 31.7 42.1 54.2 43.3 58.3 105.2 45.6 43.3 48.2 45.2 66.7 146.4 32.0 31.0 200.2 590.7 44.6 30.1 33.0 32.2 50.0 34.9 49.6 33.5 41.3 33.6 101.1 52.3 17.1 53.6 55.9 121.1 35.7 68.9 37.9 31.6 57.2 82.4 16.7 31.6 26.9 36.5 56.0 34.5 57.9 36.5 34.7 46.5 64.5 55.9 50.2 187.5 85.0 91.9 95.6 124.1 102.7 74.5 86.9 59.2 22.1 143.4 109.5 21.4 45.1 62.9 49.0 59.2 39.5 131.4 67.6 42.2 184.1 165.4 71.2 151.3 91.4 72.3 55.0 63.7 45.3 75.8 36.1 51.8 45.3 87.4 137.8 25.6 147.1 44.4 131.9 86.4 27.1 31.3 128.2 90.2 83.3 57.0 54.0 53.0 75.0 37.2 36.8 55.6 95.5 54.1 75.9 29.0 35.9 56.6 35.4 91.6 88.7 58.6 115.5 41.0 87.6 134.3 336.9 28.5 126.5 31.8 66.8 67.4 26.7 127.7 53.4 79.3 25.6 59.4 54.5 117.4 186.3 67.4 189.0 31.1 32.6 31.7 42.1 32.0 31.0 33.0 32.2 33.6 31.6 31.6 34.7 44.8 67.3 111.1 25.1 73.1 76.0 154.5 107.8 92.2 9.2 103.0 88.9 275.8 338.8 109.5 152.6 14.6 395.0 80.6 140.1 888.3 157.2 8.8 65.9 116.3 61.6 57.2 123.1 9.4 87.2 247.1 129.1 66.3 116.3 41.8 75.1 207.8 1234.6 263.2 8.4 15.0 146.1 236.0 168.8 67.6 23.8 137.0 90.0 204.5 7.5 108.2 197.2 40.2 5.5 19.0 79.7 272.5 210.3 97.4 143.6 409.8 1546.8 38.0 15.3 164.3 45.5 109.3 5.3 11.3 113.6 76.9 381.4 53.0 120.8 147.2 156.9 RNASEH1 ENSG00000171865 "Ribonuclease H1" O60930 2 3541430-3558333 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Disease variant, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA034817, HPA043037" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Cytosol "HPA034817: , HPA043037: AB_2678280" "unprognostic (1.64e-1)" "unprognostic (1.38e-1)" "unprognostic (8.81e-3)" "unprognostic (4.32e-3)" "unprognostic (1.79e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (7.83e-6)" "unprognostic (9.43e-2)" "unprognostic (8.46e-3)" "unprognostic (6.38e-2)" "unprognostic (2.29e-3)" "unprognostic (2.67e-1)" "unprognostic (4.06e-2)" "unprognostic (2.34e-2)" "unprognostic (2.11e-1)" "unprognostic (3.06e-2)" "unprognostic (2.23e-3)" 10.6 8.7 9.7 9.5 10.6 11.4 9.7 8.2 12.3 8.5 6.8 7.8 7.2 11.7 11.3 9.6 7.8 7.5 13.0 11.1 11.2 7.1 8.1 7.9 10.2 10.1 9.1 8.2 8.7 9.1 3.3 7.9 10.1 9.3 9.5 8.7 7.7 11.8 15.3 9.9 7.8 13.3 9.2 9.0 6.9 7.0 11.7 10.3 9.5 15.0 10.9 8.5 4.7 10.5 11.9 21.4 22.1 22.5 24.9 23.2 17.2 29.0 30.6 24.8 16.5 19.4 13.0 33.6 13.7 31.5 18.8 14.7 32.6 23.2 30.9 12.4 17.5 33.1 18.9 27.5 35.5 42.0 23.3 23.5 24.9 24.2 29.3 18.5 21.5 54.8 33.0 19.4 31.1 9.3 32.7 27.3 34.7 20.6 17.0 26.9 32.0 34.3 21.0 19.7 33.3 48.9 17.8 15.9 27.5 16.7 10.3 22.9 24.8 24.1 11.5 24.7 40.7 36.1 37.5 43.9 43.2 35.1 37.5 0.1 0.6 1.3 1.3 1.2 2.2 1.1 1.0 1.7 0.7 0.6 1.0 2.1 0.5 0.4 1.2 1.5 0.4 0.7 9.7 10.6 8.2 12.3 11.1 11.2 10.1 9.1 10.1 9.2 11.7 10.5 15.6 22.4 6.9 9.1 30.7 7.5 26.1 21.0 13.6 25.7 14.9 12.6 25.9 11.5 14.7 3.7 20.9 32.7 25.4 14.4 37.2 44.3 5.1 9.6 20.8 20.1 15.0 13.5 11.8 48.7 44.3 20.2 17.9 11.0 27.3 17.9 16.8 18.0 30.8 35.3 10.7 16.4 14.2 18.8 8.9 3.4 13.7 16.2 10.6 10.3 32.3 17.5 30.9 7.5 9.8 48.3 9.9 26.4 41.7 50.2 16.6 28.6 14.1 18.8 19.7 23.6 23.4 21.0 27.5 17.8 12.1 36.5 18.9 27.7 15.9 37.9 RPS7 "eS7, S7" ENSG00000171863 "Ribosomal protein S7" P62081 2 3575260-3580920 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056586 Approved Approved "Endoplasmic reticulum,Cytosol" NA Yes 820000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA056586: AB_2683179" "unprognostic (3.28e-3)" "unprognostic (1.85e-1)" "unprognostic (7.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.00e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (5.27e-4)" "unprognostic (6.41e-2)" "unprognostic (6.02e-3)" "unprognostic (7.08e-2)" "unprognostic (5.60e-2)" "unprognostic (6.27e-2)" "prognostic unfavorable (1.34e-8)" "unprognostic (3.70e-2)" "unprognostic (2.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" 1083.4 764.7 778.0 774.7 787.2 2152.4 2194.5 772.7 1112.6 1124.8 800.2 1044.1 766.0 867.6 1309.0 1281.8 1152.1 642.5 744.5 755.7 779.1 925.4 1082.6 717.6 1622.5 785.1 770.8 2394.6 1624.1 725.0 686.2 939.7 784.8 887.8 1166.3 603.2 1213.7 697.3 906.5 1419.8 866.8 895.3 805.3 964.6 1011.3 396.3 795.7 1665.6 797.7 843.0 1841.7 1038.2 1063.0 798.4 1235.6 1178.5 1778.9 1923.5 1725.8 3754.0 2913.5 1458.3 2527.9 2370.8 1371.5 2053.4 1890.4 4081.0 2369.1 1697.7 1646.1 1321.0 2038.5 2370.0 2077.4 1289.4 2743.3 1496.8 758.2 2998.2 4156.0 2622.8 1489.1 3183.4 3497.5 1475.1 3176.3 2552.1 2816.8 3707.9 2356.3 2015.2 2433.4 1661.0 2930.2 5815.8 2638.6 3679.7 1810.5 2300.9 1812.6 3670.5 2725.7 1487.1 2016.6 3028.5 771.7 2931.1 4670.0 1487.2 1615.3 3727.3 1327.2 1415.1 931.1 987.9 2387.5 2240.1 4420.9 4079.3 1489.6 3113.0 1617.9 337.1 656.8 243.1 808.8 570.7 1192.3 1411.3 1159.2 1036.9 1063.6 1172.7 1254.6 1132.2 129.3 1032.8 553.2 1016.6 1083.5 2065.3 778.0 787.2 772.7 1112.6 755.7 779.1 785.1 770.8 784.8 805.3 795.7 798.4 2544.8 496.8 793.2 28.1 3845.5 3923.3 4252.7 2961.9 3989.5 401.5 4245.2 7977.4 154.5 1720.0 1620.6 647.4 325.2 3627.9 2815.0 730.8 2606.1 2129.9 1517.5 1255.0 3316.9 1997.7 1250.9 2352.4 33.5 3434.0 5702.2 1854.2 1378.2 1489.1 1171.5 2855.2 2067.5 1515.6 2338.1 141.3 37.2 2244.0 929.8 2534.9 3126.0 485.1 2927.6 2110.0 2001.1 50.6 3250.8 1257.2 2634.4 27.6 49.8 2878.9 1747.3 1748.6 2572.7 4420.1 1233.7 4372.3 847.1 741.6 1452.9 1699.5 3261.7 1248.6 775.4 4912.8 5050.7 3716.9 3078.6 3673.3 2604.1 4351.5 COLEC11 "CL-K1, MGC3279" ENSG00000118004 "Collectin subfamily member 11" Q9BWP8 2 3594832-3644644 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 54.2;liver: 143.1" "Cell type enhanced" "Detected in many" "Fibroblasts: 37.4;Hepatic stellate cells: 89.3;Peritubular cells: 52.3;Proximal tubular cells: 127.1;Sertoli cells: 72.3" "Cancer enhanced" "Detected in many" "liver cancer: 13.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 135.7;SH-SY5Y: 111.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA035241 Uncertain "Secreted to blood" NA NA 130000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035241: AB_10600701" "unprognostic (3.35e-1)" "unprognostic (4.73e-2)" "unprognostic (2.44e-3)" "unprognostic (2.31e-3)" "unprognostic (1.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.95e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-2)" "unprognostic (2.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.96e-2)" "unprognostic (2.26e-1)" "unprognostic (9.27e-3)" "unprognostic (7.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.60e-1)" 13.8 40.6 1.0 0.9 1.0 1.9 3.3 4.8 1.9 1.8 6.9 2.8 3.5 1.2 0.4 1.6 4.4 54.2 46.6 1.4 0.9 24.8 143.1 2.4 1.9 1.3 0.5 46.4 13.8 1.2 5.8 2.4 1.3 3.3 0.6 0.5 0.6 1.1 0.6 1.4 3.8 1.1 0.4 3.8 3.1 7.4 1.1 4.0 17.0 0.8 0.2 7.1 1.0 1.3 0.2 1.4 0.7 2.5 0.0 0.0 11.7 0.7 0.0 0.3 0.2 0.7 0.2 0.3 4.0 0.1 0.4 0.4 0.1 0.4 0.3 0.2 0.8 0.6 1.4 5.0 135.7 0.2 1.0 1.6 0.1 0.2 0.0 0.4 0.1 0.8 11.1 0.8 0.0 0.1 0.0 0.8 0.6 0.2 0.9 0.0 0.0 0.5 0.0 0.3 2.1 111.7 1.6 1.1 0.8 0.3 0.5 1.0 0.0 0.0 0.7 0.6 0.5 3.2 26.2 1.5 0.3 1.3 0.6 0.7 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.2 0.9 0.3 0.1 0.2 0.1 0.0 1.0 1.0 4.8 1.9 1.4 0.9 1.3 0.5 1.3 0.4 1.1 1.3 7.3 0.0 0.0 0.7 0.6 1.0 0.0 0.0 2.8 0.5 0.1 0.3 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.1 17.6 0.0 0.3 1.1 22.0 4.2 0.0 0.0 2.2 0.0 1.4 37.4 0.0 0.6 0.0 1.3 89.3 7.9 2.5 0.0 0.9 0.1 0.0 1.9 0.3 0.5 7.5 0.8 3.6 1.0 0.0 1.4 0.0 0.5 0.2 0.1 0.0 52.3 0.0 0.2 0.0 127.1 0.0 0.1 72.3 0.3 18.0 1.3 11.6 0.6 0.9 1.2 0.7 27.0 0.0 0.1 ALLC ALC ENSG00000151360 Allantoicase Q8N6M5 2 3658200-3702671 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 17 "testis: 16.5" "Cell type enriched" "Detected in some" 4 "Early spermatids: 140.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "U-266/84: 6.1" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (5.47e-2)" "unprognostic (3.24e-2)" "unprognostic (2.91e-3)" "unprognostic (4.75e-1)" "unprognostic (2.17e-1)" "unprognostic (1.06e-1)" "unprognostic (9.83e-3)" "unprognostic (5.42e-2)" "unprognostic (1.74e-4)" "unprognostic (1.01e-2)" "unprognostic (2.73e-1)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.4 0.6 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.2 3.4 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.2 0.0 0.0 0.0 0.5 0.0 0.0 13.1 0.0 0.1 5.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DCDC2C ENSG00000214866 "Doublecortin domain containing 2C" A8MYV0 2 3703575-3848008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.1" "Group enriched" "Detected in some" 7 "Early spermatids: 171.3;Late spermatids: 59.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA045848 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA045848: AB_10961120" "unprognostic (2.63e-2)" "unprognostic (1.81e-1)" "unprognostic (3.81e-3)" "unprognostic (6.98e-2)" 0.1 0.0 0.6 0.0 0.5 0.4 0.1 0.9 0.9 0.0 1.2 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.5 0.5 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.1 0.4 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.2 4.1 0.6 0.2 0.1 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.9 0.9 0.5 0.5 0.1 0.1 0.2 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 171.3 0.0 0.4 2.3 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 59.9 5.6 0.1 0.0 15.9 0.0 0.0 0.0 0.0 0.2 0.3 0.0 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 CMPK2 "NDK, TYKi, UMP-CMPK2" ENSG00000134326 "Cytidine/uridine monophosphate kinase 2" Q5EBM0 2 6840570-6866635 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.6;salivary gland: 8.5" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 12.8;BJ hTERT+ SV40 Large T+ RasG12V: 11.9;HEL: 20.3;MOLT-4: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041430 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria Nucleoplasm "HPA041430: AB_10796674" "unprognostic (2.37e-1)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.82e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-2)" "unprognostic (8.93e-2)" "unprognostic (6.63e-2)" "unprognostic (4.54e-3)" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (1.09e-3)" "unprognostic (1.28e-1)" "unprognostic (1.77e-2)" "unprognostic (7.69e-2)" "unprognostic (4.32e-2)" 2.1 1.4 1.7 1.4 2.8 6.4 1.8 0.7 1.8 1.4 1.7 1.3 1.6 0.9 0.3 0.7 0.7 0.8 2.1 1.2 1.9 1.1 0.9 2.8 1.3 6.0 3.0 0.4 1.3 0.9 1.1 1.6 3.2 0.7 0.6 0.1 8.5 0.7 1.1 0.4 2.2 0.9 10.6 3.5 2.9 2.0 2.0 1.9 1.2 1.6 0.7 0.9 0.6 1.5 0.3 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.2 12.8 11.9 0.0 1.4 3.1 0.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.2 20.3 0.0 0.0 0.0 0.6 1.8 0.1 0.0 0.2 0.0 0.0 0.0 2.0 5.8 0.1 0.0 0.1 11.8 3.6 0.3 0.0 1.0 3.6 0.0 0.0 0.0 0.4 0.4 0.5 0.2 0.0 1.9 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.0 3.3 0.4 0.0 0.0 3.6 0.8 3.1 1.6 4.9 0.3 3.9 0.2 1.1 0.2 0.2 1.1 0.1 0.2 0.3 1.1 0.5 2.0 0.1 0.4 0.7 1.7 2.8 0.7 1.8 1.2 1.9 6.0 3.0 3.2 10.6 2.0 1.5 20.8 3.2 7.5 0.0 1.9 0.4 0.9 0.5 0.0 1.5 1.7 1.3 1.6 0.0 0.5 1.8 0.0 3.0 3.4 10.0 1.9 2.6 4.0 5.4 0.8 11.7 7.2 86.3 1.9 6.6 2.9 2.7 11.2 1.0 2.5 1.7 7.1 1.4 19.5 0.0 2.5 2.5 0.0 12.3 2.8 1.6 1.5 11.3 0.0 9.4 11.9 5.3 3.1 1.5 0.2 6.2 8.4 5.7 2.1 1.0 8.4 0.7 4.1 0.2 0.0 2.2 2.0 2.7 4.4 0.7 0.4 0.8 4.5 1.6 1.6 2.0 RSAD2 "cig5, vig1, Viperin" ENSG00000134321 "Radical S-adenosyl methionine domain containing 2" Q8WXG1 2 6865557-6898239 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Lyase Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 21.0" "Cell type enhanced" "Detected in many" "Adipocytes: 35.6;Alveolar cells type 1: 35.3;Distal enterocytes: 72.3;Erythroid cells: 44.2;Paneth cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 30.7;eosinophil: 43.3;neutrophil: 25.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 43.3" "Group enriched" "Detected in some" 5 "BJ hTERT+ SV40 Large T+: 75.7;BJ hTERT+ SV40 Large T+ RasG12V: 117.6;HMC-1: 55.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA041160, HPA049409" Approved Supported "Nucleoli fibrillar center,Endoplasmic reticulum" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Nucleoli fibrillar center" "HPA041160: AB_10795489, HPA049409: AB_2680751" "unprognostic (8.91e-2)" "unprognostic (3.85e-2)" "unprognostic (7.89e-2)" "prognostic unfavorable (4.60e-4)" "unprognostic (3.27e-1)" "unprognostic (3.25e-1)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (3.66e-3)" "unprognostic (9.47e-3)" "unprognostic (4.06e-2)" "unprognostic (1.27e-2)" "unprognostic (3.98e-2)" "unprognostic (4.54e-3)" "unprognostic (4.47e-2)" "unprognostic (1.79e-1)" 4.2 2.3 2.9 4.0 3.7 13.7 3.0 2.1 3.7 6.5 4.6 5.2 3.6 2.1 2.1 1.5 2.8 5.5 5.7 2.7 2.7 2.7 3.5 8.3 2.9 5.1 3.1 2.1 1.5 1.1 3.9 6.6 4.7 1.7 3.0 1.1 21.0 1.9 5.7 0.8 2.9 4.5 11.8 10.1 6.3 2.0 3.0 7.4 1.8 7.6 1.8 2.5 1.4 3.3 0.2 0.0 0.2 0.1 0.0 0.5 0.9 0.0 1.2 75.7 117.6 0.0 2.5 1.1 0.1 0.0 11.6 1.2 0.0 0.0 0.2 0.2 0.0 17.8 0.1 0.0 0.1 0.0 55.7 0.1 0.0 5.7 0.0 0.0 0.0 2.6 1.6 1.0 0.0 0.1 7.0 1.5 0.2 0.0 0.4 0.3 0.0 0.1 0.1 1.1 0.1 0.3 0.1 0.1 3.6 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 1.4 1.5 0.0 0.1 1.2 0.4 30.7 4.9 43.3 2.3 7.5 2.8 0.3 2.6 2.2 2.7 0.4 3.7 3.0 25.2 2.5 7.0 0.3 1.3 2.7 2.9 3.7 2.1 3.7 2.7 2.7 5.1 3.1 4.7 11.8 3.0 3.3 35.6 35.3 3.9 3.9 1.5 0.5 3.3 2.4 1.2 0.8 1.0 0.6 5.2 2.8 3.2 0.0 2.1 0.6 1.9 72.3 0.0 3.8 1.3 19.2 3.1 21.7 9.0 44.2 12.6 6.2 0.8 3.8 34.7 16.1 23.5 8.3 8.9 0.6 9.5 0.0 13.2 2.6 6.1 1.6 2.2 1.1 1.5 8.5 0.0 21.5 7.0 6.3 6.2 17.1 0.9 7.7 107.7 2.2 1.7 4.1 1.7 0.1 13.4 0.7 0.0 2.5 2.8 0.4 0.5 1.2 0.3 2.9 3.6 1.7 1.0 7.4 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.6;Inhibitory neurons: 101.7;Oligodendrocyte precursor cells: 194.5;Oligodendrocytes: 330.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 7 "granulocytes: 6.1;T-cells: 2.4" "Cell line enhanced" "Detected in many" "HEL: 39.7;HMC-1: 127.9;SH-SY5Y: 39.0;SK-MEL-30: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 9.7 28.5 21.1 4.1 46.1 13.9 10.1 59.2 36.7 24.2 1.2 5.7 2.6 26.3 7.7 4.3 7.8 7.1 8.1 17.5 24.0 7.3 1.3 5.4 6.0 30.1 27.0 19.3 30.7 38.1 12.9 5.9 33.4 9.1 5.3 23.0 4.6 6.4 9.6 5.4 3.8 11.6 21.5 23.0 2.6 4.7 30.3 7.5 3.4 10.1 5.6 4.4 7.5 73.6 0.8 5.8 30.1 6.2 6.6 13.6 23.0 0.2 0.0 1.1 2.8 0.1 0.7 2.9 3.3 0.3 8.7 0.7 10.0 0.0 0.0 1.6 2.6 39.7 0.3 11.8 0.3 0.7 127.9 21.7 0.1 2.2 0.0 0.0 0.0 9.9 17.3 0.6 0.0 4.9 20.6 1.7 11.0 0.7 13.6 15.9 21.8 2.6 1.0 10.2 9.9 39.0 0.5 4.0 39.8 3.9 1.7 2.6 0.1 3.9 10.0 10.7 4.5 10.4 3.5 0.1 14.7 8.7 14.3 1.3 0.0 6.1 1.2 0.0 1.8 0.0 1.3 0.9 0.1 0.1 2.4 1.7 0.3 0.5 0.0 0.0 0.6 0.4 21.1 46.1 59.2 36.7 17.5 24.0 30.1 27.0 33.4 21.5 30.3 73.6 27.8 3.2 4.2 34.3 2.4 2.4 0.7 0.0 1.8 4.6 2.5 2.5 11.5 2.8 1.9 0.0 75.0 2.4 5.3 15.4 1.9 3.3 5.5 6.1 15.4 13.9 25.4 18.5 176.6 5.8 3.1 10.4 2.6 10.7 8.9 31.5 23.2 1.1 4.9 10.1 101.7 2.7 0.0 1.0 1.7 14.2 4.4 1.7 24.9 17.8 1.2 7.6 10.3 194.5 330.3 3.0 11.1 10.5 3.1 3.0 2.0 0.3 1.5 39.8 0.0 16.1 5.2 1.8 6.6 5.2 1.6 1.1 9.8 19.1 2.7 1.7 ID2 "bHLHb26, GIG8" ENSG00000115738 "Inhibitor of DNA binding 2" Q02363 2 8678845-8684461 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 1209.7" "Cell type enhanced" "Detected in all" "Langerhans cells: 2393.2;monocytes: 1987.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1038.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 731.4;HEK 293: 459.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027612 Approved "Nucleoplasm,Nuclear bodies,Centrosome" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nuclear bodies" Centrosome "HPA027612: AB_10599729" "unprognostic (2.53e-1)" "unprognostic (8.16e-3)" "unprognostic (8.51e-2)" "unprognostic (6.66e-2)" "unprognostic (2.24e-1)" "prognostic favorable (9.95e-4)" "unprognostic (4.39e-2)" "unprognostic (6.31e-2)" "unprognostic (1.95e-1)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (5.98e-2)" "unprognostic (2.42e-2)" "unprognostic (1.74e-1)" "unprognostic (1.38e-3)" "unprognostic (1.92e-3)" 160.8 175.9 86.6 73.9 88.5 390.3 82.6 83.8 118.2 97.4 68.5 149.9 99.1 69.7 21.0 35.3 108.3 150.8 177.4 89.6 86.8 128.2 562.5 108.1 92.6 80.2 82.9 213.1 60.1 1209.7 65.7 70.3 85.2 125.1 124.7 69.7 114.3 142.4 18.9 69.6 99.4 85.3 81.4 107.4 66.7 13.8 90.1 73.8 223.5 41.2 47.4 110.2 76.2 95.8 2.0 132.4 56.0 68.6 86.8 13.9 208.5 156.6 18.3 68.4 29.1 266.0 7.3 4.1 175.1 262.5 16.9 115.9 36.0 1.0 20.7 731.4 459.5 101.3 81.7 333.9 24.8 76.5 266.3 23.4 3.1 30.5 1.9 19.2 1.4 6.7 6.2 113.9 109.1 45.3 7.8 9.0 102.4 338.5 102.9 9.7 38.4 75.6 71.3 60.5 103.5 146.6 8.4 117.8 12.1 142.0 19.3 44.9 27.5 83.9 14.5 126.5 9.4 8.9 7.9 88.7 106.6 230.2 46.5 110.3 76.0 1038.0 356.7 221.7 214.2 3.6 108.1 251.9 223.8 1.6 133.7 262.1 96.6 880.8 248.9 10.3 9.2 200.1 86.6 88.5 83.8 118.2 89.6 86.8 80.2 82.9 85.2 81.4 90.1 95.8 429.9 141.1 237.9 316.7 41.4 131.3 143.0 494.8 138.9 9.8 231.2 218.4 179.5 316.0 211.2 101.2 16.7 260.3 604.5 337.7 555.7 471.0 12.0 601.1 344.6 281.1 425.9 59.8 23.5 160.3 142.4 276.0 189.1 647.2 973.6 17.1 487.6 554.7 700.3 6.7 13.8 548.0 494.4 415.8 2393.2 21.7 124.2 528.4 282.8 15.9 1987.9 519.9 1070.1 26.7 3.2 69.6 301.9 32.7 86.0 130.1 231.3 264.1 66.7 27.4 19.7 166.6 185.6 2.1 39.9 97.6 104.6 666.0 690.0 16.7 323.1 51.3 KIDINS220 ARMS ENSG00000134313 "Kinase D interacting substrate 220" Q9ULH0 2 8721081-8837630 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Neurogenesis "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014790 Supported Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA014790: AB_1852460" "unprognostic (3.58e-1)" "unprognostic (1.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.78e-3)" "unprognostic (2.05e-1)" "unprognostic (2.01e-1)" "unprognostic (1.33e-2)" "prognostic favorable (9.64e-4)" "unprognostic (1.68e-1)" "unprognostic (9.21e-2)" "unprognostic (9.74e-2)" "unprognostic (7.39e-2)" "prognostic favorable (9.29e-6)" "unprognostic (4.12e-2)" "unprognostic (1.47e-1)" "unprognostic (9.27e-2)" "unprognostic (1.15e-1)" 21.2 21.6 20.9 14.5 40.6 24.4 19.6 34.9 27.5 22.3 21.6 19.6 11.4 29.3 15.3 15.1 16.6 17.7 21.9 22.1 28.9 22.1 15.7 23.6 13.1 43.9 31.5 37.7 18.8 42.8 16.9 21.4 43.4 20.0 16.5 38.0 14.5 18.0 14.5 16.7 13.8 23.6 35.7 17.1 16.5 10.6 32.0 21.6 20.0 16.7 12.3 16.7 17.9 73.9 13.5 21.3 41.8 26.8 51.4 33.9 21.9 26.2 21.6 16.4 15.0 21.5 13.5 25.2 26.1 39.4 31.5 22.5 37.9 16.1 24.0 36.4 25.7 22.7 15.9 22.6 36.3 23.6 29.9 35.3 24.9 26.1 33.7 25.1 25.9 21.6 44.7 30.8 29.2 14.8 24.2 12.7 22.7 22.3 18.8 22.7 30.7 12.7 21.7 25.4 35.4 59.3 20.8 20.7 23.6 21.7 13.3 26.6 34.4 36.1 19.0 36.6 28.5 22.4 21.1 33.5 21.1 31.2 28.1 4.1 3.4 4.2 3.6 3.9 2.6 1.9 2.6 3.0 2.7 1.8 2.7 3.1 5.3 3.2 4.6 1.8 2.4 2.2 20.9 40.6 34.9 27.5 22.1 28.9 43.9 31.5 43.4 35.7 32.0 73.9 57.1 99.3 115.7 129.6 25.2 32.8 27.6 25.1 19.9 86.2 31.3 25.0 40.2 25.8 48.6 29.5 139.7 21.5 35.0 33.9 0.0 33.3 1.3 32.3 77.8 51.8 43.3 36.4 108.3 23.6 10.0 55.0 39.8 53.1 35.4 144.0 47.8 30.9 28.8 154.8 149.2 23.4 44.7 52.7 46.0 5.9 69.6 45.9 24.9 60.9 44.2 60.5 34.0 162.3 322.2 29.0 29.8 65.5 27.3 25.7 24.5 10.5 34.4 58.0 6.6 65.4 54.2 28.1 23.4 26.4 29.5 10.9 40.2 52.1 23.9 36.0 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 171.1;Erythroid cells: 162.6;Excitatory neurons: 134.6;Horizontal cells: 141.3;Oligodendrocyte precursor cells: 177.4;Oligodendrocytes: 230.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" 2.2 2.1 16.4 2.4 23.6 26.9 9.0 20.5 18.4 7.7 26.2 7.6 2.4 4.6 2.7 15.8 2.9 3.6 4.6 18.9 21.9 7.0 0.8 6.7 1.9 21.8 22.2 5.8 1.4 29.3 5.4 3.2 22.4 14.4 8.5 15.6 5.7 2.3 1.1 11.6 3.7 3.9 20.6 2.4 6.1 2.1 21.9 2.4 4.5 1.1 4.8 3.8 8.4 29.3 14.0 4.2 12.7 5.4 5.6 12.5 7.3 6.5 2.4 8.5 5.6 1.1 21.9 3.9 7.5 15.9 6.8 10.5 11.4 13.5 12.6 12.3 19.0 16.7 5.9 0.0 6.9 0.0 5.0 9.1 7.8 8.1 5.6 18.5 4.5 5.5 14.4 3.0 7.5 3.6 4.9 0.3 5.0 6.4 15.8 7.4 20.0 0.1 12.6 2.0 7.6 23.0 6.9 41.1 6.6 6.2 7.7 4.8 2.5 14.7 7.7 11.6 19.0 1.1 0.4 4.3 23.3 2.4 5.1 4.7 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.0 0.2 16.4 23.6 20.5 18.4 18.9 21.9 21.8 22.2 22.4 20.6 21.9 29.3 7.7 19.2 12.7 171.1 1.7 3.3 4.6 33.1 0.6 20.6 18.1 12.1 12.2 7.2 54.7 40.5 8.4 3.9 1.1 28.2 5.9 5.6 9.7 3.2 19.4 13.4 37.6 162.6 134.6 1.5 1.4 12.7 21.4 2.9 8.2 14.7 4.6 0.2 1.8 141.3 107.8 59.3 32.6 1.9 17.7 12.7 5.3 5.0 14.2 33.7 29.0 98.7 0.0 177.4 230.5 88.1 42.9 7.5 0.3 19.5 1.6 10.4 45.7 8.8 6.6 10.5 15.2 12.1 24.8 24.4 5.1 1.9 2.0 1.9 12.7 66.4 ASAP2 "CENTB3, DDEF2, KIAA0400, PAP, SHAG1" ENSG00000151693 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 2" O43150 2 9206765-9405683 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 46.8" "Cell type enhanced" "Detected in many" "Astrocytes: 141.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 7 "basophil: 2.7" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018615 Approved Supported Cytosol NA NA 260000 "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB018615: AB_2242947" "unprognostic (1.19e-1)" "unprognostic (2.66e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (3.06e-2)" "unprognostic (1.08e-3)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (8.33e-2)" "unprognostic (1.58e-3)" "unprognostic (3.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.64e-2)" "unprognostic (3.24e-2)" 12.4 3.3 3.9 5.6 11.8 0.7 6.8 11.0 9.1 11.4 4.7 17.7 13.8 12.8 10.0 8.8 10.7 10.1 9.6 6.3 7.0 23.7 3.8 10.0 2.8 8.1 6.1 7.7 7.8 9.9 9.5 10.4 8.9 5.2 16.1 8.8 5.6 9.2 2.5 13.1 13.6 13.9 0.8 1.5 24.3 46.8 3.2 2.7 19.1 6.4 3.1 8.5 7.8 7.0 34.8 19.9 35.8 21.2 26.0 35.9 5.9 34.4 27.7 24.9 24.9 13.9 51.0 0.1 29.8 39.2 54.7 32.8 19.9 60.6 30.6 25.1 8.1 8.0 15.4 24.1 63.1 0.0 2.4 13.6 24.5 30.1 96.8 74.5 51.9 6.4 3.7 3.6 97.8 21.1 10.2 2.0 16.9 49.5 23.2 19.5 53.7 6.5 48.7 26.7 15.6 59.6 28.7 18.9 30.7 18.7 13.1 5.5 81.8 41.6 1.9 32.5 31.7 0.0 0.2 0.1 30.4 0.2 54.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 3.9 11.8 11.0 9.1 6.3 7.0 8.1 6.1 8.9 0.8 3.2 7.0 41.0 19.2 8.3 141.0 1.4 37.2 22.8 16.6 14.8 28.2 8.4 7.7 1.6 4.3 12.9 35.0 0.0 1.6 0.3 60.7 50.9 15.4 67.0 14.9 20.8 36.1 9.1 0.0 76.2 14.0 0.3 26.0 52.5 26.8 1.3 9.7 51.8 4.4 12.8 6.7 46.5 40.8 20.3 4.4 12.9 50.7 2.8 10.6 33.8 39.4 7.9 20.4 0.0 48.2 55.0 62.1 45.4 3.8 0.2 33.8 21.6 31.1 12.9 5.3 26.3 24.9 35.3 39.8 8.9 5.5 32.1 0.4 1.2 1.6 21.4 53.3 ITGB1BP1 "ICAP-1A, ICAP-1alpha, ICAP-1B, ICAP1, ICAP1A, ICAP1B" ENSG00000119185 "Integrin subunit beta 1 binding protein 1" O14713 2 9403475-9423528 "Predicted intracellular proteins" "Angiogenesis, Biomineralization, Cell adhesion, Differentiation, Notch signaling pathway, Transcription, Transcription regulation" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 391.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067348, HPA071538" Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA067348: AB_2732765, HPA071538: AB_2686413" "unprognostic (2.21e-1)" "unprognostic (8.31e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.39e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (4.67e-5)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (2.33e-1)" "unprognostic (6.46e-2)" "unprognostic (4.66e-2)" "prognostic unfavorable (7.10e-5)" "unprognostic (3.75e-2)" "unprognostic (2.01e-1)" "unprognostic (1.14e-3)" "unprognostic (4.08e-3)" 113.7 23.2 45.5 19.3 63.1 31.3 60.4 50.3 58.0 43.7 49.3 37.3 13.6 31.0 26.6 20.9 24.3 22.6 37.3 46.4 48.3 50.2 13.3 22.8 22.1 48.2 47.0 22.3 11.8 26.2 19.1 24.2 49.9 18.5 24.2 27.5 15.5 23.7 29.8 29.7 19.1 35.9 41.8 15.2 22.9 9.4 54.3 27.0 22.4 33.5 25.7 30.4 32.5 52.7 53.5 35.4 43.4 51.5 148.9 131.2 23.3 94.9 66.2 83.8 66.1 49.5 33.1 55.6 43.1 135.9 56.1 50.1 66.3 62.7 92.8 158.6 30.2 53.2 43.2 61.1 54.1 42.2 57.4 70.5 49.5 78.4 56.5 75.2 76.6 43.0 29.9 46.1 109.0 44.6 74.7 25.5 35.9 90.3 53.9 39.4 59.1 51.4 88.5 40.6 44.1 45.0 54.8 40.3 71.3 38.9 30.5 32.1 48.6 73.8 54.5 103.3 105.7 46.8 111.0 89.0 106.1 54.8 54.5 86.1 43.1 56.0 54.9 54.0 52.5 40.1 46.6 53.2 56.8 33.0 35.2 45.7 9.3 50.4 41.1 52.8 61.7 53.1 45.5 63.1 50.3 58.0 46.4 48.3 48.2 47.0 49.9 41.8 54.3 52.7 90.0 28.9 18.1 18.3 47.1 61.2 40.6 70.4 40.9 25.2 30.4 41.8 104.3 22.8 35.1 38.6 2.1 45.0 70.7 16.1 391.3 72.0 26.3 31.3 51.9 85.5 33.1 49.4 61.6 72.7 73.9 98.6 25.5 30.9 41.7 44.4 53.6 21.6 91.4 35.3 47.3 30.4 32.6 45.0 88.5 25.7 54.3 51.7 97.8 15.9 95.6 64.2 121.5 25.6 40.1 108.9 27.0 57.2 42.7 35.2 24.7 88.4 35.6 30.6 92.1 49.0 102.4 27.8 19.0 47.5 63.1 31.5 63.0 70.7 35.2 60.4 CPSF3 "CPSF-73, CPSF73, YSH1" ENSG00000119203 "Cleavage and polyadenylation specific factor 3" Q9UKF6 2 9423651-9473101 "Predicted intracellular proteins" "mRNA processing" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 187.6;Spermatocytes: 151.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034657 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "HPA034657: AB_10669728" "unprognostic (9.07e-2)" "unprognostic (2.23e-1)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.56e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.30e-1)" "unprognostic (6.82e-2)" "unprognostic (8.45e-3)" "unprognostic (7.39e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (3.64e-1)" "unprognostic (1.10e-2)" 14.2 15.0 10.5 18.4 11.9 23.4 16.9 11.7 13.5 14.5 12.2 17.1 13.9 13.2 23.4 16.2 14.4 11.3 11.1 10.2 11.3 15.6 19.9 12.9 26.3 11.6 10.8 10.4 12.7 14.3 10.6 16.2 12.1 12.7 19.4 11.6 11.5 13.3 15.0 19.2 13.2 16.8 11.4 15.4 13.8 50.9 12.1 32.2 16.4 12.4 30.5 16.4 11.5 13.5 35.7 79.2 85.1 74.4 46.6 54.6 89.2 56.2 60.3 67.2 63.7 100.6 64.5 112.2 51.8 49.3 61.0 61.6 96.0 66.6 81.5 73.9 70.5 95.6 37.7 94.5 40.1 92.8 61.0 49.0 44.6 84.6 61.3 38.2 55.9 71.9 117.0 46.9 64.1 78.7 96.2 121.0 125.9 89.2 54.9 92.6 107.2 94.2 59.9 52.4 46.4 110.7 55.0 41.5 63.5 71.5 40.7 63.1 42.5 53.3 46.1 54.3 70.8 56.1 80.5 118.9 62.3 95.0 57.9 32.9 34.4 23.1 22.2 39.9 23.3 25.3 20.3 23.3 50.1 23.6 20.9 22.6 5.8 38.0 38.4 33.2 36.7 30.5 10.5 11.9 11.7 13.5 10.2 11.3 11.6 10.8 12.1 11.4 12.1 13.5 7.1 6.4 12.7 3.9 15.7 10.5 10.5 26.4 8.6 12.2 7.2 6.5 11.1 8.6 19.5 5.5 8.4 39.5 19.7 9.0 19.6 22.5 187.6 14.6 15.7 11.8 12.6 36.2 9.8 22.5 43.4 13.1 8.6 14.0 8.2 19.9 6.8 14.2 26.1 21.9 9.6 11.9 26.4 20.1 9.5 33.9 11.1 20.6 19.6 10.3 36.3 18.2 16.5 8.5 13.7 16.4 7.4 12.4 15.7 6.5 9.7 18.7 18.0 20.1 6.6 12.3 38.0 151.4 43.2 16.1 8.8 27.2 13.1 26.1 15.1 8.7 IAH1 ENSG00000134330 "Isoamyl acetate hydrolyzing esterase 1 (putative)" Q2TAA2 2 9473658-9496543 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 433.4;Late spermatids: 503.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040523, HPA076040" Approved Approved Nucleoplasm NA NA 240000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA040523: AB_2677021, HPA076040: " "unprognostic (1.51e-2)" "unprognostic (1.19e-2)" "unprognostic (1.27e-1)" "unprognostic (9.41e-2)" "unprognostic (9.35e-2)" "unprognostic (2.06e-2)" "unprognostic (5.40e-2)" "unprognostic (2.28e-2)" "unprognostic (2.98e-2)" "unprognostic (5.40e-2)" "unprognostic (7.39e-2)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.64e-4)" "unprognostic (2.26e-1)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (3.91e-2)" 40.7 47.5 27.5 16.9 28.2 27.3 34.1 32.6 37.3 33.3 32.6 41.2 20.0 30.4 31.4 26.6 28.2 23.0 56.9 27.4 29.6 39.4 46.0 31.3 27.0 27.6 27.8 35.6 23.3 45.6 31.1 24.2 28.6 26.6 29.1 22.3 22.4 29.3 43.0 22.6 26.2 27.4 27.5 25.9 29.9 65.8 29.0 28.5 28.8 72.6 31.0 30.6 29.9 31.8 41.0 40.8 4.7 0.5 73.4 140.7 0.9 33.4 76.8 48.7 46.4 0.5 44.2 21.1 17.6 106.7 35.2 27.8 15.4 32.2 48.5 81.2 26.8 26.7 16.1 27.5 139.6 0.1 21.2 85.1 92.9 36.6 42.6 93.6 49.2 37.8 0.4 13.3 100.1 39.4 106.6 4.2 6.4 53.6 20.6 26.0 0.1 6.1 79.4 21.1 29.0 56.2 26.0 37.2 52.6 2.4 37.9 46.4 38.6 38.7 17.0 17.5 52.6 10.6 0.7 8.2 53.4 16.6 44.3 33.3 38.0 31.9 30.2 35.3 33.8 38.5 35.2 34.6 49.6 32.7 27.2 30.9 23.0 37.6 42.8 52.4 46.0 25.6 27.5 28.2 32.6 37.3 27.4 29.6 27.6 27.8 28.6 27.5 29.0 31.8 44.4 32.1 26.2 25.1 53.7 89.9 100.5 92.4 21.6 33.6 41.3 51.2 45.4 52.9 40.1 49.7 12.5 74.2 65.0 36.2 92.0 68.9 433.4 49.9 56.9 30.1 25.7 41.4 43.2 76.9 109.8 73.5 16.8 50.1 36.8 74.0 36.4 53.1 87.4 42.1 35.1 28.6 42.7 78.2 95.2 503.0 93.8 66.3 92.5 19.7 116.8 44.0 80.3 23.1 44.4 90.5 37.3 73.0 38.5 75.6 68.0 138.8 42.7 57.4 98.6 82.8 75.2 243.2 48.8 41.4 95.8 44.5 64.9 87.0 47.5 89.5 ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 154.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010738, HPA051575" Approved Supported Cytosol NA NA 300000 "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA010738: AB_1078100, HPA051575: AB_2681539" "unprognostic (2.28e-1)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (5.15e-2)" "unprognostic (2.12e-3)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (3.69e-1)" "unprognostic (3.53e-3)" "unprognostic (3.13e-1)" "unprognostic (3.82e-3)" "unprognostic (8.63e-2)" "unprognostic (2.61e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (4.23e-5)" 10.3 5.5 8.7 9.1 8.6 5.8 10.4 7.8 10.6 8.7 9.5 5.4 4.1 7.2 11.4 10.0 6.5 9.0 6.7 8.6 9.4 4.7 4.6 14.6 8.5 9.7 8.3 8.9 4.1 7.9 4.2 20.1 9.4 4.0 6.8 4.5 6.2 6.3 6.9 11.1 6.1 8.6 8.3 9.3 5.1 9.9 9.1 9.6 6.6 6.8 12.7 10.4 7.1 10.4 10.0 18.2 23.2 25.9 45.9 34.7 45.4 8.6 25.4 16.1 24.6 19.2 31.6 33.4 18.1 18.8 42.1 21.9 16.4 29.4 22.6 8.4 12.1 15.8 14.7 13.9 68.0 20.7 17.8 41.2 32.2 25.1 47.5 26.6 46.0 8.7 30.0 12.3 17.3 8.7 8.5 23.4 19.2 13.7 4.6 14.3 21.6 20.5 25.8 18.7 11.7 28.6 14.9 16.5 30.1 27.0 6.6 19.4 29.0 25.5 12.0 19.1 22.1 15.1 17.5 29.6 20.2 11.1 31.1 5.0 3.7 2.8 1.0 3.7 1.9 1.7 0.9 1.1 2.3 0.9 0.9 1.0 5.5 1.2 2.5 0.7 1.1 0.9 8.7 8.6 7.8 10.6 8.6 9.4 9.7 8.3 9.4 8.3 9.1 10.4 53.8 48.1 66.9 19.6 34.5 130.0 48.2 37.0 19.9 25.2 40.8 26.4 3.6 27.1 38.8 31.3 54.2 29.8 37.7 20.7 5.9 23.7 72.1 30.0 32.0 45.1 19.7 16.8 66.7 19.4 45.1 44.1 13.7 51.5 30.9 31.3 41.4 13.5 34.6 10.1 46.2 13.8 12.2 80.4 84.5 16.0 19.0 76.9 40.9 42.2 40.3 12.9 16.5 26.7 41.5 20.9 18.3 16.1 23.2 57.2 12.9 7.0 37.2 41.4 39.5 79.4 27.3 35.7 35.2 33.7 154.7 56.0 30.1 17.7 15.4 104.3 YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007925, CAB010286" Approved Supported Nucleoplasm,Cytosol NA NA 49000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB010286: AB_2218221, HPA007925: AB_1844340" "unprognostic (2.65e-2)" "unprognostic (3.99e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (1.53e-1)" "unprognostic (5.78e-3)" "prognostic unfavorable (9.83e-6)" "unprognostic (4.90e-3)" "unprognostic (2.98e-2)" "unprognostic (5.51e-2)" "unprognostic (6.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.95e-2)" "unprognostic (6.74e-2)" "unprognostic (9.75e-2)" "unprognostic (1.63e-1)" "unprognostic (4.39e-3)" 144.6 141.0 190.8 106.1 223.2 178.4 153.6 216.5 239.1 177.0 149.4 161.2 119.4 184.3 141.6 187.3 136.5 122.6 218.7 205.1 229.7 140.0 116.3 119.3 132.0 218.6 203.8 163.2 201.5 131.9 112.9 123.2 212.4 161.1 133.0 143.6 120.2 140.2 53.5 121.5 116.2 177.4 203.9 89.8 127.5 144.6 205.7 148.2 137.6 62.1 141.1 144.4 161.8 280.5 316.1 465.2 412.0 400.3 316.6 434.5 385.7 421.6 412.3 432.5 360.2 352.9 269.3 404.4 214.0 608.5 451.3 288.5 462.8 459.7 553.6 1003.0 374.8 378.8 268.9 379.9 241.1 369.1 219.7 295.8 264.5 473.6 305.9 394.9 493.5 285.6 378.5 236.8 539.3 219.3 658.2 374.4 700.7 351.9 527.5 473.0 533.3 497.4 478.8 276.9 390.1 659.9 384.1 392.2 317.3 343.8 244.4 187.0 453.9 539.6 380.7 473.4 654.4 239.3 351.4 526.6 461.8 378.9 458.8 99.5 102.7 120.5 207.8 137.8 255.6 151.9 192.8 223.5 144.2 147.8 103.6 170.1 31.1 252.0 137.0 73.1 208.4 344.1 190.8 223.2 216.5 239.1 205.1 229.7 218.6 203.8 212.4 203.9 205.7 280.5 186.6 51.3 67.3 26.1 144.0 316.7 366.5 339.0 143.4 201.4 198.4 153.7 82.6 90.1 143.4 136.1 27.1 261.6 189.9 209.9 416.7 371.5 281.9 132.9 175.8 191.0 187.1 179.2 57.3 283.7 615.3 242.0 115.2 131.6 125.0 152.5 84.9 97.9 215.3 572.0 45.1 129.2 270.6 111.9 228.3 360.5 174.0 132.3 295.3 30.0 195.0 229.2 155.5 39.7 186.6 261.2 150.9 250.5 187.9 323.7 135.9 278.8 111.7 105.8 197.2 191.5 312.7 432.2 205.8 252.1 355.3 238.6 217.7 252.9 186.5 457.3 TAF1B "RAF1B, RAFI63, SL1, TAFI63" ENSG00000115750 "TATA-box binding protein associated factor, RNA polymerase I subunit B" Q53T94 2 9843443-9934416 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071254 Supported Nucleoplasm,Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA071254: " "unprognostic (1.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (8.58e-5)" "unprognostic (1.44e-3)" "unprognostic (5.43e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.94e-7)" "unprognostic (9.17e-2)" "unprognostic (3.29e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (2.98e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.59e-1)" "unprognostic (2.49e-1)" "unprognostic (2.79e-2)" "unprognostic (1.49e-2)" 7.2 7.6 4.1 8.4 4.1 7.1 8.7 5.3 4.2 6.9 6.4 5.9 5.1 9.7 6.6 9.6 9.6 7.2 4.8 3.8 5.1 13.3 6.3 8.7 11.4 3.9 5.4 5.7 4.4 14.7 3.7 13.0 3.7 9.0 5.7 9.0 8.1 9.0 2.8 8.6 4.2 8.1 3.8 7.1 6.1 11.0 5.4 11.4 10.5 3.4 12.7 7.9 6.0 4.7 25.1 20.4 29.2 9.6 14.1 21.2 52.7 29.9 23.3 25.3 23.3 19.1 18.1 27.1 13.6 21.3 26.7 15.0 26.9 31.7 27.3 31.3 35.9 31.5 8.9 28.3 19.5 22.1 32.4 17.0 16.5 21.4 28.5 20.8 37.4 14.8 19.8 27.2 25.0 15.3 16.6 20.1 37.7 15.6 17.5 10.2 27.2 8.0 24.9 24.3 12.3 33.6 23.5 28.9 21.9 18.9 10.4 17.4 20.4 31.9 39.8 31.1 35.7 14.9 19.9 39.7 18.4 24.8 26.7 3.6 9.1 6.2 12.1 15.5 12.1 11.1 10.2 14.3 13.4 11.7 6.3 10.0 0.5 10.2 12.4 10.6 11.1 5.2 4.1 4.1 5.3 4.2 3.8 5.1 3.9 5.4 3.7 3.8 5.4 4.7 12.5 19.2 22.0 22.2 13.1 16.2 29.9 17.9 19.9 24.5 8.0 6.1 4.0 2.8 26.0 12.9 27.1 25.0 12.6 2.4 13.7 19.5 11.6 26.8 21.0 15.4 1.8 10.5 38.8 18.9 37.4 18.4 13.7 17.3 8.8 12.7 6.8 4.7 12.7 15.2 27.1 3.3 8.2 12.0 11.5 3.8 19.0 14.6 0.0 15.0 15.5 25.5 15.5 32.6 23.5 15.7 3.8 13.2 16.6 9.5 1.7 26.5 29.7 21.0 19.7 15.9 16.2 47.6 33.9 19.7 13.2 23.7 15.1 24.8 4.4 18.7 GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 119.6;skin 1: 87.7;vagina: 66.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Cytotrophoblasts: 61.9;Extravillous trophoblasts: 80.5;Suprabasal keratinocytes: 132.7;Syncytiotrophoblasts: 184.6;Urothelial cells: 104.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "BEWO: 212.3;RT4: 41.4;SK-BR-3: 112.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Vesicles "HPA005798: AB_1079026, HPA006420: AB_1079025" "unprognostic (2.26e-3)" "unprognostic (5.80e-2)" "unprognostic (8.35e-2)" "unprognostic (7.33e-3)" "unprognostic (2.70e-1)" "unprognostic (2.76e-2)" "unprognostic (4.43e-3)" "unprognostic (6.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-4)" "unprognostic (3.66e-1)" "unprognostic (3.40e-1)" "unprognostic (4.04e-2)" "unprognostic (2.14e-1)" 4.5 1.3 2.2 1.2 2.3 8.7 39.8 0.8 2.8 31.0 1.0 1.5 1.2 1.0 7.3 119.6 2.2 3.0 2.5 2.7 2.5 4.0 12.2 5.0 1.0 0.8 1.5 0.4 4.2 29.0 3.6 26.7 0.9 11.4 1.0 11.4 44.7 7.3 1.1 87.7 0.7 0.7 0.6 0.8 3.7 3.2 4.3 0.9 2.9 0.4 26.1 13.9 66.9 1.7 10.9 0.2 1.2 3.0 0.4 0.5 212.3 1.0 1.5 0.7 1.2 0.9 7.5 1.4 0.4 0.1 1.5 6.5 13.0 1.4 3.1 3.2 5.9 0.3 2.3 4.3 0.3 0.7 1.2 0.4 5.5 6.0 0.0 0.0 1.1 2.3 2.2 4.1 0.0 14.3 2.2 1.7 0.8 3.5 2.5 0.9 1.0 1.9 1.4 41.4 2.4 1.6 2.0 112.3 2.7 17.4 13.7 0.4 1.2 0.6 2.6 3.3 1.3 2.7 1.7 1.5 0.6 1.7 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 1.7 2.2 2.3 0.8 2.8 2.7 2.5 0.8 1.5 0.9 0.6 4.3 1.7 2.2 3.2 8.1 3.9 1.2 40.0 23.1 10.7 2.8 25.5 37.1 19.9 2.1 1.5 31.1 20.2 62.6 61.9 1.3 1.2 0.0 2.9 6.4 4.5 1.3 4.2 3.5 0.0 14.6 9.1 80.5 5.4 3.1 9.6 10.2 0.4 2.5 7.7 7.7 11.8 6.0 0.8 4.1 1.0 15.7 3.0 0.0 10.6 21.4 1.9 1.0 1.1 0.0 4.0 1.0 5.7 0.1 0.4 1.0 31.5 0.1 2.4 18.6 11.5 0.0 3.0 3.7 9.6 5.1 35.2 132.7 184.6 2.1 0.1 1.2 104.6 KLF11 "MODY7, TIEG2, Tieg3" ENSG00000172059 "Kruppel like factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Suprabasal keratinocytes: 86.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: AB_2683664" "unprognostic (9.66e-3)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (3.02e-3)" "unprognostic (2.63e-3)" "unprognostic (6.34e-2)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (3.08e-2)" "unprognostic (2.48e-3)" "unprognostic (8.96e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-2)" "unprognostic (9.24e-2)" 27.7 15.6 4.0 7.6 3.2 27.8 22.3 8.3 3.9 13.5 4.1 17.9 7.5 20.0 9.7 13.2 13.7 18.1 19.1 2.9 3.9 15.7 35.2 22.4 9.3 3.7 3.3 23.9 54.2 18.3 2.5 19.5 3.4 10.1 9.3 3.0 15.9 14.8 12.1 26.9 8.7 16.8 3.2 18.8 12.4 30.0 3.5 4.0 16.5 27.3 5.5 12.6 13.1 5.1 6.9 3.3 7.8 0.7 5.3 9.4 18.8 7.9 7.9 4.4 4.6 7.8 15.8 0.0 13.9 9.6 17.9 1.6 6.8 6.1 2.9 47.6 5.2 3.5 9.7 1.6 5.2 14.6 22.1 14.7 22.3 8.4 2.3 11.4 3.9 1.3 9.7 30.8 4.6 8.2 0.0 2.7 12.5 5.6 6.7 7.8 0.2 13.6 10.8 8.5 10.0 6.2 12.0 24.5 23.4 12.2 5.7 19.6 11.2 19.3 15.9 14.7 2.6 27.9 36.0 18.7 5.0 3.8 10.4 0.0 8.2 2.0 2.6 12.3 0.8 3.2 1.8 1.9 7.3 2.9 0.5 1.1 0.2 6.6 14.8 0.3 3.0 5.4 4.0 3.2 8.3 3.9 2.9 3.9 3.7 3.3 3.4 3.2 3.5 5.1 58.8 6.4 4.6 0.3 12.5 60.5 17.7 5.5 25.6 6.2 14.3 13.2 3.5 10.0 6.1 7.3 6.2 3.2 10.1 2.5 29.4 8.2 135.0 9.1 21.5 33.3 7.1 4.6 1.7 8.5 4.2 17.5 9.7 26.6 8.2 15.5 37.5 38.1 12.5 3.3 1.4 7.0 16.2 32.4 42.4 25.9 14.6 22.0 30.2 1.0 16.6 2.2 3.1 0.5 0.3 8.9 1.5 16.6 5.3 15.0 6.1 8.4 4.3 5.8 32.9 10.4 35.7 13.8 39.0 13.1 86.2 8.2 10.8 11.2 7.8 11.7 CYS1 ENSG00000205795 "Cystin 1" Q717R9 2 10056780-10080944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 124.6;pancreas: 33.6" "Group enriched" "Detected in many" 4 "Cholangiocytes: 32.9;Collecting duct cells: 51.5;Distal tubular cells: 70.5;Muller glia cells: 48.0;Proximal tubular cells: 54.1" "Cancer enhanced" "Detected in many" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "RPTEC TERT1: 111.5" "Low region specificity" "Detected in all" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (8.48e-2)" "unprognostic (8.00e-2)" "unprognostic (9.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.56e-1)" "unprognostic (5.71e-2)" "unprognostic (1.94e-2)" "unprognostic (9.53e-2)" "unprognostic (7.05e-2)" "unprognostic (7.03e-2)" "prognostic favorable (1.27e-5)" "unprognostic (2.19e-3)" "unprognostic (1.47e-1)" "unprognostic (8.93e-2)" "unprognostic (1.20e-2)" 3.1 1.6 6.0 1.2 5.7 0.0 1.9 5.3 7.8 8.4 15.5 11.7 2.5 7.8 3.6 3.9 6.3 9.1 6.1 5.5 5.5 124.6 1.0 6.1 1.1 6.9 6.0 12.4 33.6 1.7 7.2 0.1 5.6 4.9 1.8 2.2 2.9 7.2 1.0 1.5 3.4 5.9 6.4 2.9 3.9 1.0 5.2 0.5 5.6 2.1 2.1 3.5 6.6 5.9 0.0 0.3 0.0 0.0 0.5 2.6 0.1 0.4 1.6 0.2 0.1 0.2 0.0 0.0 0.4 4.4 0.9 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 111.5 0.0 0.0 0.5 0.4 0.3 0.0 1.3 2.0 0.2 0.0 6.0 3.2 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 5.7 5.3 7.8 5.5 5.5 6.9 6.0 5.6 6.4 5.2 5.9 0.9 6.4 1.1 1.0 1.0 0.5 0.1 0.6 0.0 10.3 0.5 5.5 7.3 32.9 0.0 51.5 0.0 0.0 0.2 0.0 70.5 7.0 0.1 0.3 0.9 0.6 0.0 0.0 2.9 1.1 0.6 8.8 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.3 0.0 3.4 1.0 0.0 2.8 0.0 48.0 0.0 3.0 0.6 0.4 0.0 4.5 0.1 0.3 0.0 54.1 0.0 1.9 0.0 0.5 3.9 0.0 1.4 0.0 0.1 0.0 0.3 0.1 0.0 0.1 RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "DNA replication" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 44.2;esophagus: 18.4;intestine: 19.7;lymphoid tissue: 58.1" "Group enriched" "Detected in many" 4 "Erythroid cells: 214.0;Extravillous trophoblasts: 254.1;Plasma cells: 248.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056994 Enhanced Supported Cytosol Yes Yes 13000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA056994: AB_2683304" "unprognostic (2.10e-2)" "unprognostic (1.62e-1)" "unprognostic (6.40e-3)" "unprognostic (4.42e-3)" "unprognostic (5.70e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (1.39e-5)" "unprognostic (1.04e-3)" "unprognostic (6.67e-3)" "unprognostic (4.53e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.11e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.38e-1)" "unprognostic (2.09e-2)" 1.5 1.3 0.3 12.4 0.3 44.2 2.9 0.5 0.4 3.0 1.9 14.2 9.4 2.2 0.7 18.4 0.8 1.1 0.5 0.3 0.3 0.9 3.2 2.4 35.5 0.4 0.4 0.3 1.1 0.3 0.2 4.6 0.4 0.9 19.7 0.2 2.1 0.5 0.1 3.7 7.5 6.1 0.3 11.1 6.0 2.9 0.8 58.1 0.9 0.1 37.6 6.0 4.6 0.5 110.2 25.0 127.1 49.9 7.4 22.5 116.8 209.2 128.6 170.2 187.9 70.8 59.1 114.4 9.5 88.6 151.1 55.0 188.0 136.6 198.0 210.7 41.8 146.3 52.1 105.1 0.8 146.7 87.4 8.1 3.4 234.6 16.2 27.7 103.3 110.4 63.4 328.6 214.3 57.1 167.3 90.9 83.0 133.3 103.6 87.6 187.0 67.8 87.1 62.7 67.7 56.2 198.0 116.6 17.3 51.8 69.2 31.4 57.6 93.1 125.1 66.9 289.6 212.1 184.9 195.9 51.0 134.4 107.7 0.3 0.1 0.1 1.2 0.0 0.0 0.1 0.3 0.8 0.1 0.1 0.1 0.4 0.4 0.8 0.0 0.1 0.2 0.2 0.3 0.3 0.5 0.4 0.3 0.3 0.4 0.4 0.4 0.3 0.8 0.5 0.2 3.2 1.5 0.0 25.0 10.5 3.0 9.2 1.2 0.0 3.9 4.4 1.4 1.5 2.3 0.0 0.0 42.3 5.6 12.9 1.9 1.2 3.9 2.2 3.5 4.2 0.0 214.0 0.1 0.0 254.1 11.2 11.7 3.6 5.7 12.2 3.9 3.7 47.9 0.0 0.0 26.9 2.0 7.2 8.8 6.8 0.3 5.0 0.0 1.0 0.0 0.0 7.2 0.0 0.0 0.5 0.3 0.4 248.0 1.5 2.4 2.1 4.6 0.0 0.0 0.2 14.6 22.9 34.0 51.5 1.6 48.7 11.9 1.2 36.7 5.6 HPCAL1 "BDR1, HLP2, VILIP-3" ENSG00000115756 "Hippocalcin like 1" P37235 2 10302889-10427617 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 182.4" "Cell type enhanced" "Detected in all" "Horizontal cells: 228.8;Intestinal goblet cells: 308.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 310.6;HDLM-2: 324.5;PC-3: 354.2;U-87 MG: 334.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Supported NA NA 92000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA043245: AB_2678385" "unprognostic (3.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.11e-5)" "unprognostic (2.73e-1)" "unprognostic (6.76e-3)" "unprognostic (5.26e-2)" "unprognostic (7.36e-3)" "unprognostic (4.16e-2)" "unprognostic (1.04e-1)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (4.06e-1)" "unprognostic (3.64e-2)" "unprognostic (1.04e-1)" "unprognostic (2.55e-1)" 47.1 62.1 123.2 24.1 140.0 14.4 31.4 182.4 146.9 42.8 54.3 43.2 35.2 90.4 9.3 16.9 40.3 15.1 49.6 114.1 132.2 71.4 62.5 102.3 27.7 129.9 114.8 15.5 52.6 8.5 65.0 22.1 138.2 21.9 21.3 21.2 20.4 9.0 27.3 18.8 63.7 28.1 84.0 47.3 73.3 46.8 123.8 16.6 33.1 15.1 17.3 20.9 23.0 81.1 51.8 88.6 6.2 25.5 13.8 35.4 59.8 41.0 110.5 58.3 63.6 31.4 128.5 20.1 47.3 30.6 310.6 18.9 16.7 56.8 26.1 324.5 30.1 44.8 94.8 69.2 61.4 27.8 86.5 19.3 25.9 139.1 43.1 207.3 77.7 30.5 41.8 129.1 105.5 70.5 23.2 168.4 32.5 43.2 354.2 29.5 24.3 88.8 85.0 14.8 22.8 152.5 43.0 51.6 102.7 21.6 16.2 72.5 94.2 72.8 22.4 77.7 69.8 38.5 44.7 10.5 334.9 67.4 174.0 24.5 50.9 61.9 21.6 39.9 23.6 26.7 38.9 27.4 43.5 21.3 46.3 30.7 70.0 24.5 36.3 15.7 36.0 29.5 123.2 140.0 182.4 146.9 114.1 132.2 129.9 114.8 138.2 84.0 123.8 81.1 88.6 83.3 86.8 9.4 48.2 33.8 23.4 4.3 11.4 76.9 19.9 12.4 15.9 30.0 16.9 18.4 16.7 4.9 30.1 39.7 93.9 48.6 25.7 10.3 15.1 72.2 62.6 18.7 23.5 37.1 145.6 22.9 53.0 10.8 55.2 26.3 81.8 32.7 67.6 228.8 23.3 308.8 4.1 79.2 77.9 19.2 17.1 65.1 56.9 31.9 43.9 51.7 46.4 12.5 10.3 46.1 64.5 10.9 45.5 14.8 111.7 100.3 6.8 33.6 6.6 18.2 14.5 20.8 14.9 15.6 30.1 41.3 45.0 6.2 44.8 19.2 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448327 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 560.8;Late spermatids: 834.9;Prostatic glandular cells: 412.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 47.2 23.2 31.0 69.3 31.5 172.9 33.0 30.5 32.2 33.5 48.5 64.8 32.4 66.0 49.2 29.4 56.3 43.7 55.9 29.9 33.0 132.2 92.1 52.4 111.0 32.4 33.0 54.8 61.8 99.6 92.5 20.0 30.6 91.1 72.0 46.2 27.0 55.1 163.3 29.2 41.6 71.2 34.1 42.9 51.5 133.3 34.0 77.1 58.5 73.5 149.1 113.6 26.9 35.7 166.8 130.6 177.1 211.4 31.1 92.4 410.1 234.6 114.9 216.3 99.9 697.3 75.4 870.2 114.6 143.6 208.6 30.2 549.1 265.5 261.2 334.0 231.5 398.1 212.2 429.9 250.8 680.1 91.8 62.5 70.5 490.1 608.3 111.4 176.3 237.6 674.2 274.3 121.7 109.0 680.1 267.3 324.9 228.3 418.8 478.5 556.0 586.3 130.9 119.5 246.6 209.9 293.6 88.8 121.8 135.7 60.0 300.5 124.7 174.4 362.6 227.9 511.7 128.0 416.1 780.8 156.7 443.6 109.9 0.0 1.5 3.0 2.9 2.9 3.3 14.8 4.1 4.8 3.4 15.0 2.8 4.5 0.5 1.4 1.8 12.2 4.4 3.2 31.0 31.5 30.5 32.2 29.9 33.0 32.4 33.0 30.6 34.1 34.0 35.7 78.2 44.8 161.4 7.5 228.9 58.0 123.7 48.8 19.4 36.8 53.2 68.3 55.1 81.5 33.9 40.5 31.3 1.5 188.1 77.7 72.4 50.6 560.8 90.9 66.2 52.2 271.0 111.3 7.5 27.6 70.0 63.2 204.4 127.6 58.9 103.8 14.6 50.3 46.8 6.7 4.1 234.1 22.4 32.1 22.4 834.9 15.5 191.8 23.2 8.4 22.1 126.3 37.0 4.5 2.4 28.6 64.5 11.3 287.4 412.4 31.6 154.1 21.9 77.4 0.0 223.0 79.9 186.5 75.8 52.2 87.5 3.4 133.0 30.2 180.5 142.2 NOL10 "FLJ14075, PQBP5" ENSG00000115761 "Nucleolar protein 10" Q9BSC4 2 10570754-10689987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 189.3;Late spermatids: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035286, HPA043075" Approved Supported Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoli "HPA035286: AB_2674552, HPA043075: AB_10794652" "unprognostic (6.53e-3)" "unprognostic (1.61e-1)" "unprognostic (6.84e-2)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.31e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (1.43e-7)" "unprognostic (1.25e-1)" "unprognostic (3.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.61e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (7.51e-5)" "unprognostic (2.43e-2)" "unprognostic (2.92e-1)" "unprognostic (3.82e-1)" "unprognostic (3.87e-2)" 12.6 14.8 6.6 10.1 8.0 16.2 11.3 10.2 8.2 9.6 5.1 10.8 8.1 9.3 11.0 13.7 7.8 6.6 11.2 7.5 7.1 13.7 14.4 9.0 10.3 6.2 6.6 9.1 16.0 12.1 8.3 10.9 6.1 10.0 10.6 6.2 12.9 8.6 19.4 13.1 9.0 8.8 6.3 9.6 11.7 13.1 7.3 9.9 10.2 11.9 11.7 12.3 10.7 8.8 19.7 33.2 18.6 32.6 22.1 24.2 34.9 33.1 25.8 36.9 27.5 37.5 24.0 45.4 19.5 32.1 30.8 24.5 43.8 38.7 43.6 32.2 33.8 43.8 20.3 46.6 28.0 52.8 23.9 22.6 28.7 40.7 39.1 16.7 25.5 25.0 59.4 28.5 33.9 38.2 36.4 37.4 49.7 51.8 28.8 32.0 49.2 41.4 26.1 30.6 31.6 34.3 24.2 39.4 29.1 20.2 20.8 20.4 24.2 33.8 41.1 33.6 53.9 37.9 63.7 52.4 28.1 49.7 41.5 1.5 3.9 2.2 4.0 5.2 5.9 4.8 4.2 4.2 4.9 3.7 3.2 4.8 0.5 4.8 5.9 3.1 6.0 2.8 6.6 8.0 10.2 8.2 7.5 7.1 6.2 6.6 6.1 6.3 7.3 8.8 22.2 16.0 16.7 31.6 17.1 33.0 29.9 17.2 17.1 13.0 16.3 12.8 19.2 11.5 16.1 12.9 12.5 32.7 16.4 9.9 15.6 27.5 189.3 8.9 19.5 22.9 11.4 19.8 72.9 24.1 33.7 20.2 13.3 17.8 14.0 20.2 12.5 12.2 15.4 16.8 57.6 12.4 18.3 9.8 13.0 163.0 17.1 12.2 8.8 36.5 23.8 13.9 20.6 54.3 54.2 19.0 7.0 16.6 22.1 30.3 10.6 17.0 7.3 16.7 13.1 36.4 22.5 26.4 42.1 17.8 34.2 29.6 17.7 30.4 18.3 22.3 ATP6V1C2 "ATP6C2, VMA5" ENSG00000143882 "ATPase H+ transporting V1 subunit C2" Q8NEY4 2 10721100-10785110 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 80.3;salivary gland: 103.2;skin 1: 87.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.2;Distal tubular cells: 45.0;Enteroendocrine cells: 41.5;Glandular and luminal cells: 73.4;Ionocytes: 93.6;Syncytiotrophoblasts: 169.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BEWO: 78.4;SK-BR-3: 27.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034734, HPA067305" Approved Uncertain Mitochondria NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA034734: AB_2674305, HPA067305: AB_2732763" "unprognostic (2.29e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (6.55e-3)" "unprognostic (2.69e-2)" "unprognostic (2.20e-2)" "unprognostic (7.03e-3)" "unprognostic (8.53e-2)" "unprognostic (1.29e-1)" "unprognostic (2.11e-2)" "unprognostic (6.77e-2)" "unprognostic (2.73e-2)" "prognostic unfavorable (1.12e-11)" "unprognostic (6.17e-2)" "unprognostic (3.30e-1)" "unprognostic (2.37e-1)" "unprognostic (8.27e-2)" 3.4 4.0 1.4 1.7 2.1 4.3 5.7 0.7 1.4 57.5 0.9 2.4 0.9 4.7 80.3 18.3 2.9 0.9 3.0 1.8 0.8 43.3 6.0 2.8 2.0 0.7 0.8 2.9 3.8 1.2 23.5 36.7 0.6 5.1 2.5 1.6 103.2 6.8 1.0 87.6 2.7 0.2 0.6 4.0 2.4 2.0 0.9 0.5 3.8 0.0 5.0 2.0 19.0 1.6 0.6 0.9 2.4 2.7 0.0 0.0 78.4 1.1 0.0 0.0 0.0 1.5 1.9 1.9 1.3 0.0 1.2 1.2 1.3 0.1 0.1 1.1 2.6 0.9 1.4 2.7 0.0 1.8 1.0 0.0 0.3 0.0 0.0 1.8 0.0 0.6 0.9 3.6 0.0 2.1 0.7 2.9 1.8 1.1 0.8 1.6 1.4 5.5 0.0 1.7 1.9 2.3 0.7 27.2 0.8 10.0 2.4 4.0 0.4 0.9 1.8 1.1 1.1 6.2 2.5 1.1 1.1 1.5 0.8 0.0 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.2 1.4 2.1 0.7 1.4 1.8 0.8 0.7 0.8 0.6 0.6 0.9 1.6 13.6 0.0 2.6 0.3 1.0 0.4 3.7 2.8 1.2 0.0 1.4 1.8 0.9 0.0 6.6 7.3 0.0 147.2 0.8 0.3 45.0 0.1 0.7 31.3 13.4 1.4 41.5 0.0 2.4 0.2 33.0 2.7 1.1 73.4 2.5 0.3 0.0 0.2 13.8 0.0 1.2 0.2 93.6 0.8 0.8 0.4 0.6 0.9 0.0 2.8 0.0 0.0 0.0 0.5 1.3 0.2 0.1 0.0 4.0 1.1 0.0 1.1 4.4 0.0 0.0 0.7 1.2 0.2 1.2 0.6 2.4 169.1 1.0 0.3 0.8 0.4 PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 1202.1;Plasma cells: 883.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Cytosol" "Intracellular and membrane" NA NA 15000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Cytosol" "CAB034347: AB_2299360, HPA034652: AB_2674263, HPA034653: AB_10601982" "unprognostic (8.16e-2)" "prognostic unfavorable (1.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.20e-4)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" "unprognostic (5.25e-3)" "unprognostic (6.03e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (6.59e-2)" "unprognostic (2.34e-1)" "unprognostic (1.38e-2)" "unprognostic (3.69e-3)" 118.3 112.3 54.5 155.8 64.6 140.8 124.9 57.1 66.7 178.8 71.2 156.0 122.4 131.6 418.5 98.2 133.5 96.7 113.4 55.9 60.8 130.3 260.5 103.8 118.1 61.1 55.4 99.8 252.1 149.7 74.0 171.3 60.7 127.4 171.6 48.0 184.1 135.5 59.3 64.3 121.5 155.5 60.9 107.4 155.4 55.1 62.6 86.6 363.3 59.4 153.7 130.9 75.7 66.4 287.0 304.6 425.7 672.6 535.6 459.4 753.4 677.8 625.9 348.3 465.1 435.1 548.5 460.9 464.7 668.9 674.1 228.0 324.1 568.3 371.1 363.2 253.4 374.2 228.4 713.2 577.5 387.9 268.9 334.2 428.4 338.1 603.3 642.1 798.0 171.8 328.0 963.6 348.7 338.8 150.5 400.8 356.6 923.4 236.4 355.7 433.0 846.4 498.3 339.9 272.0 543.2 267.6 387.0 396.2 547.8 136.8 648.5 395.0 324.4 409.8 296.3 399.1 900.0 596.6 297.1 438.5 479.6 464.8 276.1 200.0 95.5 198.4 210.9 219.0 197.6 154.2 187.6 215.0 161.0 74.3 125.1 35.0 241.6 161.4 268.9 174.4 319.2 54.5 64.6 57.1 66.7 55.9 60.8 61.1 55.4 60.7 60.9 62.6 66.4 217.1 57.7 124.2 17.6 193.9 103.0 294.2 552.8 61.5 69.1 121.1 91.7 35.9 148.7 264.6 196.8 29.2 456.3 164.6 125.8 43.0 338.6 8.2 146.5 382.9 176.2 157.7 89.2 47.4 240.6 1202.1 228.2 138.1 255.0 131.3 210.6 211.3 355.6 413.1 42.1 30.5 276.3 170.9 155.7 149.8 16.2 121.2 145.9 199.3 15.0 132.1 106.5 142.2 32.6 25.3 175.4 131.2 135.1 883.2 385.4 99.9 149.6 145.8 60.1 85.5 96.9 225.3 98.5 117.9 95.4 102.6 554.1 125.7 254.3 248.3 265.3 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 28.9;choroid plexus: 32.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Extravillous trophoblasts: 14.4;Inhibitory neurons: 8.8;Oligodendrocyte precursor cells: 18.1;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 14.3;MCF7: 5.1;T-47d: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.1 0.0 20.6 0.1 28.9 0.0 0.2 0.0 21.5 0.0 32.1 1.2 0.2 0.6 0.0 0.2 0.1 0.1 0.7 28.8 14.7 0.4 0.0 0.3 0.1 0.0 5.3 0.0 0.9 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.5 0.3 0.5 12.5 0.3 0.0 0.0 0.0 0.6 0.0 15.8 0.1 14.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 2.1 0.1 1.5 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.1 6.1 0.7 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.9 0.0 21.5 28.8 14.7 0.0 5.3 0.0 0.6 12.5 15.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 2.0 0.8 1.4 1.4 0.0 0.0 0.0 2.1 0.0 0.1 1.6 0.0 0.0 2.2 0.8 0.3 0.9 1.2 0.0 9.3 0.0 14.4 0.7 0.0 2.0 0.0 0.2 0.0 0.0 0.2 0.0 8.8 0.2 0.0 0.0 0.0 3.4 0.3 0.1 0.0 1.9 0.0 0.3 0.0 18.1 1.4 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 7.7 0.0 0.4 0.3 0.1 C2orf50 FLJ25143 ENSG00000150873 "Chromosome 2 open reading frame 50" Q96LR7 2 11133128-11151317 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.7;fallopian tube: 7.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 8.4;Endometrial ciliated cells: 21.5;Excitatory neurons: 9.7;Respiratory ciliated cells: 27.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.0" "HPA062894, HPA067681" Enhanced Uncertain "Golgi apparatus,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" Cytosol "HPA062894: AB_2684897, HPA067681: " "unprognostic (6.29e-2)" "unprognostic (1.33e-1)" "unprognostic (3.53e-4)" "unprognostic (1.92e-3)" "unprognostic (3.35e-2)" "unprognostic (6.19e-2)" "unprognostic (3.55e-1)" "unprognostic (1.31e-1)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (2.00e-2)" "unprognostic (2.45e-1)" "unprognostic (3.97e-4)" "unprognostic (7.03e-2)" "unprognostic (2.92e-1)" "unprognostic (8.25e-3)" "unprognostic (7.36e-2)" 0.1 0.2 1.5 0.2 1.8 0.5 0.2 0.4 1.6 0.4 5.7 0.1 0.3 0.3 0.2 0.1 7.4 0.1 0.0 1.3 1.4 0.2 0.1 0.6 0.3 1.8 1.9 0.3 0.2 0.1 0.7 0.1 0.5 0.2 0.2 1.5 0.3 0.1 0.2 0.4 0.1 0.1 1.0 0.3 0.2 0.3 1.0 0.2 0.2 0.0 0.1 0.1 0.0 1.0 0.1 0.5 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 1.0 0.2 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.7 0.1 0.3 0.2 0.2 0.1 0.5 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.7 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.2 0.3 0.1 0.6 0.2 0.2 0.2 0.1 0.1 1.5 1.8 0.4 1.6 1.3 1.4 1.8 1.9 0.5 1.0 1.0 1.0 0.0 0.0 1.8 0.7 0.5 0.0 0.5 0.5 0.0 0.4 0.4 0.5 0.4 0.0 3.5 0.0 8.4 0.0 0.1 0.0 0.0 0.3 0.2 21.5 0.4 0.0 0.0 0.0 9.7 0.2 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 1.7 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.9 0.0 2.5 0.4 0.2 0.0 1.5 0.0 0.1 0.0 0.2 27.1 3.0 0.0 1.0 0.5 0.5 1.4 0.0 0.0 0.0 0.3 0.9 0.0 0.1 SLC66A3 "C2orf22, MGC33602, PQLC3" ENSG00000162976 "Solute carrier family 66 member 3" Q8N755 2 11155198-11178870 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 15.5;Cytotrophoblasts: 17.5;Extravillous trophoblasts: 82.4;Fibroblasts: 16.1;Hofbauer cells: 56.3" "Cancer enhanced" "Detected in all" "testis cancer: 72.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 64.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061607 Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA061607: AB_2797264" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (5.55e-2)" "unprognostic (1.65e-2)" "unprognostic (2.16e-1)" "unprognostic (1.09e-3)" "unprognostic (9.11e-2)" "unprognostic (3.14e-1)" "unprognostic (2.24e-1)" "unprognostic (4.93e-3)" "unprognostic (2.93e-1)" "unprognostic (1.19e-2)" "unprognostic (1.12e-1)" "unprognostic (2.21e-1)" "unprognostic (2.34e-1)" "unprognostic (4.00e-2)" 30.6 26.3 9.7 17.3 9.8 9.9 29.2 10.2 14.0 38.4 17.0 17.6 10.8 23.8 47.3 14.3 19.8 27.8 15.1 9.6 10.2 25.8 17.5 27.0 22.5 12.0 10.1 29.9 29.0 13.2 5.8 14.4 12.0 22.6 19.3 2.5 17.1 19.8 8.5 14.7 15.5 21.4 11.3 39.8 20.0 11.6 10.2 14.3 17.3 17.1 16.8 22.5 17.2 14.2 7.1 23.3 4.3 13.4 64.6 43.9 15.5 14.8 19.3 6.8 8.0 4.3 27.3 2.5 10.5 28.5 29.3 9.1 6.9 7.3 6.8 43.8 3.2 6.5 2.7 3.0 26.1 3.3 19.5 31.7 24.5 4.3 9.7 14.5 15.5 15.3 6.2 14.8 18.8 31.6 4.8 6.6 9.1 25.2 7.6 6.2 7.2 7.7 25.8 11.6 1.6 7.2 12.4 37.9 27.9 19.1 33.9 12.2 22.0 9.6 3.8 10.2 4.1 25.2 19.6 1.2 24.9 15.5 19.4 79.4 153.7 150.3 68.8 194.9 60.7 42.4 65.6 66.7 153.6 31.9 35.9 49.5 9.5 59.9 207.4 28.7 73.2 166.2 9.7 9.8 10.2 14.0 9.6 10.2 12.0 10.1 12.0 11.3 10.2 14.2 15.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 17.5 11.9 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 82.4 16.1 0.0 0.0 0.0 0.0 0.0 0.0 56.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 11.2 2.2 0.0 0.0 0.0 ROCK2 ENSG00000134318 "Rho associated coiled-coil containing protein kinase 2" O75116 2 11179759-11348330 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 280.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007459, CAB008666, HPA044109" Approved Supported Cytosol NA NA 710000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "CAB008666: AB_1622617, HPA007459: AB_1079828, HPA044109: AB_2678813" "unprognostic (4.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.18e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "unprognostic (2.71e-1)" "unprognostic (1.39e-2)" "unprognostic (2.72e-1)" "unprognostic (3.62e-2)" "unprognostic (6.66e-2)" "unprognostic (3.83e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.57e-5)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-2)" "unprognostic (3.47e-2)" 36.4 9.3 6.7 13.5 16.3 6.8 22.3 19.1 14.3 18.7 0.8 22.6 16.7 22.0 10.3 16.2 13.6 15.6 17.0 12.1 3.5 14.5 16.5 16.9 10.1 1.7 4.4 19.0 11.7 12.8 5.9 24.9 1.4 17.4 26.2 13.5 14.6 18.1 30.4 8.5 19.2 27.9 2.0 16.4 14.1 7.8 6.4 8.4 13.9 28.9 8.8 21.1 11.0 10.4 17.5 41.7 33.8 33.2 59.7 41.6 21.6 40.4 37.7 25.8 27.1 39.8 37.2 21.9 23.4 64.5 31.3 18.9 24.7 23.4 40.6 31.2 14.7 43.8 70.6 79.7 21.4 24.7 12.1 32.6 14.6 31.9 22.6 21.0 42.0 11.9 38.6 8.6 38.8 14.8 18.2 12.7 18.8 36.9 25.3 21.7 74.2 7.0 14.0 48.8 15.9 16.9 79.6 27.4 27.4 25.5 11.3 13.6 57.3 52.9 38.2 21.2 36.0 6.8 8.9 18.8 22.8 28.2 75.4 0.9 0.4 0.4 0.6 0.4 0.7 0.3 0.4 0.4 0.3 0.5 0.4 0.4 0.6 0.8 0.4 0.6 0.4 0.2 6.7 16.3 19.1 14.3 12.1 3.5 1.7 4.4 1.4 2.0 6.4 10.4 114.5 115.4 79.1 81.3 16.0 39.9 43.0 15.3 21.1 35.7 33.5 41.1 107.0 37.1 53.1 22.0 58.4 26.3 20.4 97.7 1.9 27.1 11.0 53.6 141.2 90.3 21.2 22.5 280.4 39.5 19.1 64.0 18.3 55.3 29.0 36.9 56.0 43.1 19.6 80.8 158.1 92.2 10.2 20.3 27.0 4.9 43.8 30.4 23.2 107.7 20.6 38.4 15.5 99.0 66.9 39.1 43.6 78.6 16.2 53.5 45.3 15.7 32.7 48.5 131.5 70.0 118.5 30.3 24.6 19.9 27.8 31.5 18.5 34.2 54.8 40.7 E2F6 E2F-6 ENSG00000169016 "E2F transcription factor 6" O75461 2 11444375-11466177 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 7.8" "Lineage enriched" "Detected in single" 17 "granulocytes: 7.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA075185 Supported Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA075185: AB_2732282" "unprognostic (7.13e-2)" "unprognostic (2.44e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (7.13e-4)" "unprognostic (4.18e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.90e-1)" "unprognostic (3.05e-3)" "unprognostic (7.58e-2)" "unprognostic (3.17e-3)" "unprognostic (3.64e-3)" "unprognostic (2.08e-3)" "unprognostic (2.72e-2)" "unprognostic (1.02e-1)" "unprognostic (9.01e-2)" "unprognostic (2.13e-1)" 5.5 5.2 5.0 2.5 5.3 3.8 4.3 5.1 6.2 3.3 5.1 4.5 2.8 5.4 3.9 2.7 4.9 3.1 7.6 4.8 5.8 2.6 2.8 3.0 2.4 5.3 5.4 4.7 4.6 3.4 5.0 3.1 5.1 3.3 2.2 3.5 3.6 3.4 14.6 3.7 3.6 4.4 5.1 3.2 4.9 2.8 5.2 2.5 2.7 11.5 1.9 4.0 3.0 5.2 4.2 5.2 10.7 6.0 4.8 3.9 8.0 4.0 7.1 4.6 4.2 10.3 5.6 8.2 4.5 4.6 9.3 3.1 7.6 5.9 4.8 10.6 11.3 14.9 4.0 12.8 9.4 15.4 14.7 6.7 5.5 5.0 5.9 3.9 4.2 7.1 11.3 15.3 3.7 10.1 8.9 16.9 15.3 5.1 6.7 15.6 12.1 8.4 5.0 3.7 9.2 19.1 4.6 6.7 18.8 4.6 6.2 7.7 3.5 6.6 8.5 4.2 9.0 22.0 17.4 19.9 7.2 14.5 10.3 7.8 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 5.0 5.3 5.1 6.2 4.8 5.8 5.3 5.4 5.1 5.1 5.2 5.2 15.7 6.4 4.8 7.2 8.4 24.3 23.6 10.6 13.6 12.4 14.5 9.7 9.0 10.0 8.4 3.7 16.7 17.3 8.5 3.4 7.9 11.7 1.4 11.0 14.1 12.2 6.7 3.4 13.9 11.0 13.9 14.3 13.3 14.0 0.0 13.6 8.6 8.8 12.5 13.5 14.9 4.7 8.2 5.4 11.5 2.6 8.7 11.3 17.8 6.5 7.0 10.1 5.2 3.5 20.8 9.4 3.7 11.3 6.1 21.3 5.3 8.4 4.1 11.8 0.0 22.2 12.3 15.7 48.2 8.2 21.9 22.2 8.4 11.7 6.0 16.7 GREB1 KIAA0575 ENSG00000196208 "Growth regulating estrogen receptor binding 1" Q4ZG55 2 11482341-11642788 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "ovary: 278.3" "Cell type enriched" "Detected in many" 9 "Granulosa cells: 545.2" "Cancer enhanced" "Detected in many" "prostate cancer: 17.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 40.3;Hep G2: 39.6;MCF7: 61.8;SH-SY5Y: 40.5;SK-MEL-30: 30.4;T-47d: 138.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024616, HPA027843, HPA028416" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Mitochondria, Cytosol" "HPA024616: AB_10599728, HPA027843: AB_10601103, HPA028416: AB_10601344" "unprognostic (1.52e-2)" "unprognostic (4.63e-1)" "unprognostic (1.46e-1)" "prognostic favorable (1.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.38e-1)" "unprognostic (3.68e-1)" "unprognostic (3.63e-2)" "unprognostic (7.51e-4)" "unprognostic (2.42e-2)" "unprognostic (3.34e-1)" "unprognostic (2.46e-3)" "unprognostic (4.80e-2)" 1.8 3.4 8.5 0.7 9.6 0.4 13.7 2.1 9.9 60.2 0.8 1.0 0.7 61.3 7.0 0.6 53.4 2.8 4.6 7.8 20.4 1.8 3.1 1.4 0.6 8.7 8.5 278.3 7.6 0.7 8.9 3.0 4.4 63.4 0.2 1.5 1.1 3.8 4.0 2.7 0.9 12.8 3.2 0.2 3.0 14.9 10.7 0.3 0.6 4.8 0.3 1.7 21.5 6.5 0.1 1.0 40.3 0.5 0.2 0.2 1.8 0.0 0.1 0.1 0.3 0.3 0.2 2.5 0.3 0.0 6.9 0.2 3.1 0.2 0.1 5.1 3.6 0.4 0.3 39.6 0.5 0.3 2.1 0.5 2.2 0.6 0.4 0.4 0.0 3.9 0.5 1.0 0.3 61.8 1.2 2.0 13.0 0.1 0.1 29.1 0.0 1.9 0.1 0.0 11.8 40.5 0.9 1.1 30.4 5.2 138.0 0.7 0.0 4.1 2.0 0.4 0.1 6.0 4.4 24.7 6.8 11.9 1.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.1 0.1 0.0 8.5 9.6 2.1 9.9 7.8 20.4 8.7 8.5 4.4 3.2 10.7 6.5 0.4 0.0 0.5 20.2 0.7 0.8 1.9 0.0 0.6 4.8 24.7 13.7 8.3 5.7 0.6 0.0 2.1 0.2 0.1 0.1 0.0 0.3 0.8 35.7 36.0 1.3 0.0 0.0 15.0 0.2 3.6 16.9 0.0 23.4 3.8 545.2 0.7 8.9 3.2 3.3 46.9 0.0 0.0 0.0 1.2 2.5 20.2 1.4 5.4 1.0 0.0 0.2 0.0 11.6 20.9 0.4 0.0 55.3 5.0 14.3 0.0 2.5 2.9 0.5 0.0 7.2 14.8 1.1 2.9 0.3 0.3 0.3 1.1 33.1 0.0 2.5 NTSR2 NTR2 ENSG00000169006 "Neurotensin receptor 2" O95665 2 11658178-11670195 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 58 "brain: 85.4;choroid plexus: 43.7" "Cell type enriched" "Detected in some" 32 "Astrocytes: 32.7" "Cancer enriched" "Detected in single" 15 "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (5.40e-2)" "unprognostic (2.30e-2)" "unprognostic (2.36e-2)" "unprognostic (5.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.80e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-1)" "unprognostic (1.64e-1)" 0.5 0.9 74.8 0.0 84.2 0.0 0.2 67.7 78.2 0.0 43.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.7 75.8 0.0 0.0 0.0 0.0 65.8 85.4 1.1 0.2 0.0 0.2 0.0 68.9 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 60.5 0.0 0.0 0.2 82.9 0.0 0.0 0.0 0.0 0.0 0.0 60.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.8 84.2 67.7 78.2 65.7 75.8 65.8 85.4 68.9 60.5 82.9 60.8 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.5;tongue: 137.2" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1705.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 36.2 15.0 29.0 14.9 30.6 8.6 36.7 24.2 24.9 25.1 21.9 16.7 11.9 16.6 19.0 40.5 15.6 13.0 20.1 21.0 32.1 14.9 27.0 16.1 22.3 31.8 38.2 31.5 9.9 23.1 34.2 11.7 35.3 13.7 8.5 14.8 27.3 14.1 193.5 13.4 19.7 13.0 14.1 14.8 14.9 57.4 35.0 16.1 14.6 137.2 26.3 19.9 23.1 18.8 16.2 18.0 15.9 34.9 71.4 77.9 7.8 22.2 38.7 14.0 24.3 6.9 15.4 8.2 2.9 18.6 41.6 17.3 17.4 49.2 12.8 32.9 9.8 20.3 11.5 9.7 25.1 14.1 90.1 71.1 21.7 57.9 22.6 41.7 28.0 19.6 27.4 68.3 10.4 6.4 13.5 12.0 16.2 5.5 18.9 18.1 28.6 52.0 36.9 10.0 42.8 33.6 8.0 19.7 51.9 15.0 4.9 7.9 19.5 22.1 19.9 14.4 19.0 108.0 92.0 15.2 31.3 24.7 16.6 11.2 2.9 13.4 10.3 2.3 11.2 7.3 9.9 10.1 2.7 5.1 8.6 7.2 1.1 9.5 2.3 10.3 12.2 3.7 29.0 30.6 24.2 24.9 21.0 32.1 31.8 38.2 35.3 14.1 35.0 18.8 15.6 22.4 56.8 167.8 46.1 19.1 45.1 12.6 18.8 48.6 32.8 22.9 59.6 31.5 43.9 11.0 85.5 8.7 68.0 21.2 7.9 23.0 338.4 27.8 44.4 25.8 36.2 9.7 55.7 28.0 6.0 28.8 19.4 76.5 35.4 13.1 17.5 48.7 8.9 48.8 71.7 25.2 22.4 15.7 39.4 1705.8 119.0 25.5 17.8 21.5 15.4 14.7 66.9 41.7 43.5 36.5 29.7 179.8 76.0 34.9 5.4 4.8 52.0 49.0 32.9 32.4 18.4 20.6 19.7 5.5 11.9 12.3 73.2 26.6 16.3 31.3 TRIB2 "GS3955, TRB2" ENSG00000071575 "Tribbles pseudokinase 2" Q92519 2 12716889-12742734 "Enzymes, Predicted membrane proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 104.3;Muller glia cells: 100.3" "Cancer enhanced" "Detected in all" "melanoma: 74.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 48.8" "Group enriched" "Detected in many" 8 "B-cells: 12.2;NK-cells: 19.3;T-cells: 48.8" "Cell line enhanced" "Detected in many" "AN3-CA: 183.5;HEL: 185.7;K-562: 258.0;SK-MEL-30: 189.3;WM-115: 246.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001305 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA001305: AB_1080371" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (4.31e-3)" "unprognostic (1.86e-3)" "unprognostic (6.68e-3)" "unprognostic (3.93e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (3.32e-2)" "unprognostic (2.52e-3)" "unprognostic (1.67e-2)" "unprognostic (1.08e-3)" "unprognostic (1.30e-1)" "unprognostic (8.71e-2)" "unprognostic (9.59e-2)" "unprognostic (2.13e-2)" 43.3 63.1 29.1 38.9 29.9 16.8 38.3 36.1 35.2 21.7 30.5 27.0 17.8 44.4 43.4 15.5 23.4 28.8 51.0 31.6 37.7 92.3 21.0 39.8 72.7 31.4 30.8 97.8 26.2 18.0 20.0 46.6 29.7 33.0 13.4 137.8 20.4 25.6 14.3 16.9 25.2 34.2 29.7 79.7 41.8 28.5 32.4 39.3 23.9 19.5 69.6 48.4 19.5 28.0 0.2 0.4 138.8 183.5 48.9 44.7 0.2 7.9 7.5 4.9 7.9 0.9 15.3 16.3 5.5 16.9 0.8 2.3 10.3 16.1 4.2 18.3 28.9 185.7 0.4 2.7 60.7 10.7 68.0 41.7 16.0 20.3 5.6 48.9 22.1 23.8 258.0 0.3 7.9 1.7 24.4 44.8 66.1 7.0 18.0 0.0 46.2 6.7 31.9 23.4 118.9 56.6 1.1 7.4 189.3 41.4 0.2 1.1 13.9 65.3 32.0 0.6 17.8 0.1 0.2 22.9 35.2 36.3 246.7 1.7 0.2 3.2 12.7 0.0 15.8 9.6 26.1 13.8 1.2 12.2 15.0 9.2 0.5 19.3 0.2 0.1 48.8 8.9 29.1 29.9 36.1 35.2 31.6 37.7 31.4 30.8 29.7 29.7 32.4 28.0 52.2 3.2 8.3 25.5 12.5 6.1 9.1 26.9 19.4 55.0 7.9 8.6 17.1 12.8 15.6 16.5 31.3 2.6 17.5 0.7 7.9 17.2 4.3 9.7 11.6 43.9 0.0 22.1 13.5 104.3 0.2 11.3 20.9 15.9 34.2 77.3 59.6 6.7 5.8 20.2 6.9 0.4 28.5 5.1 8.2 14.3 77.3 3.8 30.2 13.1 3.0 100.3 26.8 59.8 2.7 45.3 0.2 74.4 21.0 11.6 0.3 1.0 17.9 66.7 52.6 9.9 41.2 1.0 6.0 5.7 5.4 0.8 27.1 30.5 0.8 32.5 LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 32.2;intestine: 41.0" "Group enriched" "Detected in some" 8 "Cytotrophoblasts: 162.2;Syncytiotrophoblasts: 207.8" "Cancer enhanced" "Detected in many" "colorectal cancer: 35.0" "Group enriched" "Detected in many" 7 "amygdala: 19.7;basal ganglia: 10.8;cerebral cortex: 18.1;hippocampal formation: 13.0;white matter: 6.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 9.4;hTCEpi: 18.0;RT4: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA047703: AB_2680123" "unprognostic (1.05e-2)" "unprognostic (9.22e-2)" "unprognostic (2.24e-3)" "unprognostic (1.13e-1)" "unprognostic (4.28e-2)" "unprognostic (7.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (1.20e-1)" "unprognostic (9.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.13e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-3)" "unprognostic (1.36e-1)" 0.5 1.4 19.7 4.9 10.8 0.0 2.4 0.0 18.1 10.6 0.0 41.0 26.3 2.7 32.2 28.6 2.9 3.4 2.1 13.0 2.0 4.0 1.4 3.0 0.2 0.0 0.2 8.2 3.2 5.2 3.3 5.3 0.0 13.6 36.2 0.9 13.9 2.0 0.9 18.5 25.3 2.8 0.0 0.2 3.0 12.3 1.4 1.3 2.2 0.1 1.4 14.8 16.6 6.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.2 2.5 0.6 0.5 0.0 0.3 0.0 0.0 0.3 0.0 9.4 1.0 4.2 1.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 18.0 0.0 5.9 0.2 0.0 0.0 0.0 0.0 1.3 7.8 0.0 0.2 0.8 0.0 4.0 0.0 0.0 0.1 6.9 49.3 4.3 2.0 0.0 1.8 0.0 0.3 0.0 0.0 2.9 8.2 0.7 0.0 3.2 0.0 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.7 10.8 0.0 18.1 13.0 2.0 0.0 0.2 0.0 0.0 1.4 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 162.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 22.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 207.8 0.0 0.0 0.0 0.0 NBAS NAG ENSG00000151779 "NBAS subunit of NRZ tethering complex" A2RRP1 2 15166914-15561334 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.8;Inhibitory neurons: 187.9;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 159.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036817 Approved Approved "Nuclear membrane,Nucleoli,Golgi apparatus" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nuclear membrane, Nucleoli" "HPA036817: AB_10670925" "unprognostic (1.72e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.80e-2)" "unprognostic (4.16e-2)" "unprognostic (1.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.53e-2)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "prognostic unfavorable (5.84e-5)" 16.8 21.0 37.4 7.2 38.8 16.1 15.9 37.7 42.7 18.8 35.7 22.7 8.2 18.4 13.7 17.2 18.8 8.1 38.3 37.2 36.3 19.9 21.6 15.8 9.4 37.0 35.2 22.5 34.4 16.3 29.6 10.1 38.7 19.0 10.5 13.4 15.4 10.4 30.5 21.8 20.1 11.8 34.4 21.1 24.5 41.2 37.2 14.5 17.4 17.7 9.1 19.7 16.5 38.1 10.5 13.7 14.8 10.7 37.8 41.5 15.2 19.1 20.8 14.5 14.6 13.8 15.0 13.4 4.3 29.3 15.1 12.5 16.5 23.9 17.2 13.5 10.4 51.3 11.5 38.8 38.8 13.4 25.1 27.3 18.9 19.2 32.8 30.2 30.4 18.7 40.6 15.0 22.4 13.0 11.2 30.1 12.8 17.1 12.8 11.7 26.0 16.2 30.5 14.0 8.7 14.2 16.2 13.4 25.2 18.3 9.4 12.0 26.6 18.5 11.2 13.5 13.9 22.1 20.3 18.7 33.1 15.5 16.8 1.5 4.4 2.5 5.7 3.1 6.7 4.1 4.2 7.3 4.0 3.4 4.2 4.3 0.8 7.2 7.5 4.5 5.3 2.9 37.4 38.8 37.7 42.7 37.2 36.3 37.0 35.2 38.7 34.4 37.2 38.1 16.1 19.2 13.8 96.6 15.1 7.4 9.3 11.9 12.0 17.3 11.7 9.4 32.3 17.2 13.8 18.4 29.2 11.5 15.1 9.4 0.0 11.1 39.3 22.2 21.3 14.6 7.3 38.7 217.8 14.0 13.1 13.4 20.9 14.8 38.6 30.2 8.9 9.1 9.0 13.5 187.9 14.8 10.2 6.9 8.0 61.9 11.5 11.6 5.4 106.8 18.4 12.5 9.2 159.3 159.2 8.6 9.5 16.6 27.2 9.2 39.3 8.5 26.0 25.5 0.0 24.7 16.3 33.7 22.4 12.9 11.2 10.4 19.9 70.0 12.5 7.6 DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15634346 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 362.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Supported Nucleoplasm,Cytosol NA NA 86000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "CAB012280: , HPA034502: AB_10794321, HPA034503: AB_10795025" "unprognostic (9.94e-2)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (8.36e-3)" "unprognostic (9.28e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (9.09e-9)" "unprognostic (2.55e-1)" "unprognostic (2.05e-1)" "unprognostic (4.81e-3)" "unprognostic (3.89e-2)" "unprognostic (2.03e-1)" "prognostic favorable (9.69e-4)" "unprognostic (3.80e-1)" "unprognostic (1.34e-1)" "unprognostic (4.94e-2)" "unprognostic (1.20e-3)" 52.8 53.4 32.6 39.0 33.5 37.8 61.7 36.1 44.2 49.9 39.6 54.3 45.0 45.4 48.0 56.5 42.4 31.7 97.6 33.8 37.1 76.7 62.0 38.9 35.3 36.8 32.6 45.7 59.0 89.5 46.7 50.9 36.0 44.6 58.0 55.5 52.9 47.8 157.9 50.3 46.0 56.5 34.7 33.8 50.5 42.5 35.3 47.0 62.3 134.2 46.8 48.4 41.0 36.3 84.1 127.1 172.3 126.2 148.1 125.5 193.3 176.8 142.6 165.1 135.9 203.0 80.7 221.8 80.4 202.8 120.9 118.8 245.5 166.8 170.7 94.6 154.3 244.5 150.6 241.8 110.2 204.5 102.3 101.2 105.9 140.6 129.6 100.8 151.0 98.4 253.4 61.8 161.9 112.2 110.3 126.7 221.0 205.6 104.4 125.0 276.8 152.6 178.9 161.9 136.6 169.3 124.3 118.0 154.8 123.2 83.6 77.5 133.7 132.1 139.8 84.2 197.2 84.5 169.3 296.2 120.5 153.7 128.4 32.4 34.5 20.3 31.0 42.0 33.2 28.6 35.8 37.0 38.8 30.5 39.9 35.8 3.0 38.5 42.0 30.1 38.1 34.1 32.6 33.5 36.1 44.2 33.8 37.1 36.8 32.6 36.0 34.7 35.3 36.3 41.3 80.1 57.6 25.8 34.9 40.3 57.2 96.4 31.9 58.9 50.3 41.5 362.7 67.2 78.6 90.1 52.1 112.1 29.0 43.7 142.8 112.3 23.1 49.2 69.6 57.2 52.1 64.2 52.1 120.3 108.5 67.0 28.5 51.2 57.0 49.3 47.5 123.0 53.4 45.4 48.6 69.8 83.4 30.3 19.7 19.5 72.7 28.1 49.8 29.0 41.2 60.1 55.6 45.8 49.0 107.2 52.4 78.2 32.8 31.3 74.5 170.2 80.6 75.9 59.2 51.3 94.6 174.0 76.8 30.0 42.3 80.2 30.7 73.5 74.1 36.6 MYCN "bHLHe37, MYCNOT, N-myc, NMYC" ENSG00000134323 "MYCN proto-oncogene, bHLH transcription factor" P04198 2 15940550-15947007 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 9.5" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 84.2;Granulosa cells: 26.4" "Cancer enriched" "Detected in many" 5 "testis cancer: 45.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 44.1;BEWO: 239.1;HMC-1: 57.3;NTERA-2: 91.3;RH-30: 63.3;SuSa: 40.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057420 Approved Nucleoplasm,Nucleoli NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoli Nucleoplasm "HPA057420: AB_2683434" "unprognostic (8.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-2)" "unprognostic (4.11e-1)" "unprognostic (2.46e-2)" "unprognostic (1.23e-2)" "unprognostic (3.03e-2)" "unprognostic (1.81e-1)" "unprognostic (3.35e-3)" "unprognostic (3.09e-2)" "unprognostic (2.09e-1)" "unprognostic (1.12e-3)" "unprognostic (8.89e-2)" "unprognostic (2.47e-1)" "unprognostic (4.90e-2)" "unprognostic (1.23e-1)" 0.4 0.8 3.5 0.6 3.5 0.9 0.4 3.1 3.9 1.5 0.8 0.6 1.6 0.9 0.1 0.7 0.5 0.3 1.2 3.4 3.0 3.3 0.8 0.7 1.6 4.4 3.9 5.1 0.2 0.1 0.3 9.5 3.7 0.1 0.5 1.0 4.7 0.2 0.4 1.4 0.9 0.3 3.3 0.3 4.6 3.6 3.5 2.9 2.9 0.7 1.2 0.5 0.4 5.9 0.0 0.0 44.1 0.0 0.0 0.0 239.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 4.2 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 57.3 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.0 0.8 0.4 0.2 91.3 2.1 0.0 0.0 63.3 12.8 0.0 3.1 1.0 16.0 0.0 0.1 0.0 40.9 0.1 0.0 0.0 0.0 1.2 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.5 3.1 3.9 3.4 3.0 4.4 3.9 3.7 3.3 3.5 5.9 0.8 0.0 0.0 0.7 0.0 0.5 0.1 0.0 0.0 2.6 0.1 0.9 0.7 0.0 0.0 0.0 0.0 5.6 0.0 0.2 0.0 0.0 1.2 0.5 0.1 2.7 0.0 4.2 2.0 0.0 84.2 1.0 2.6 0.8 0.0 26.4 0.0 0.6 2.4 0.0 4.2 0.9 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.1 1.0 0.0 10.1 7.5 0.3 1.1 0.4 0.0 0.0 0.4 3.2 0.0 0.2 0.0 4.2 0.7 1.3 3.7 0.3 0.0 11.5 0.0 9.4 0.3 0.0 CYRIA "CYRI-A, DKFZP566A1524, FAM49A, FLJ11080" ENSG00000197872 "CYFIP related Rac1 interactor A" Q9H0Q0 2 16549459-16666331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 46.4;Extravillous trophoblasts: 102.6;Hofbauer cells: 37.1;Macrophages: 24.0;Syncytiotrophoblasts: 150.0" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 53.1;HUVEC TERT2: 43.1;RH-30: 95.6;SK-BR-3: 28.2;TIME: 34.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017847, HPA060398" Approved Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 41: Macrophages - Immune response" Nucleoplasm "CAB017847: , HPA060398: AB_2684275" "unprognostic (3.45e-1)" "unprognostic (1.83e-2)" "unprognostic (6.50e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-1)" "unprognostic (7.78e-2)" "unprognostic (8.61e-2)" "unprognostic (3.83e-2)" "unprognostic (2.61e-1)" "unprognostic (2.00e-2)" "unprognostic (5.74e-2)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.83e-6)" "unprognostic (1.32e-2)" "unprognostic (3.43e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (4.46e-4)" 13.9 11.0 29.8 21.1 34.2 23.2 8.8 4.6 37.9 15.8 2.5 7.9 3.4 10.1 2.2 5.1 9.1 10.9 4.1 37.2 18.3 1.9 7.6 13.0 19.2 9.9 20.6 11.9 2.8 1.1 6.4 20.0 13.2 8.2 6.3 6.4 4.1 8.6 8.4 3.6 6.5 10.7 14.5 27.8 4.2 1.9 24.1 5.0 40.9 7.3 18.1 10.3 9.4 19.6 0.5 0.0 6.1 0.3 6.2 1.8 18.0 0.0 0.1 0.0 0.0 0.1 0.0 2.9 1.0 0.0 4.2 3.7 1.5 2.4 0.0 6.8 0.2 3.8 0.1 0.0 3.3 0.1 53.1 3.1 2.3 0.5 0.0 4.9 43.1 0.1 0.4 4.8 3.8 0.4 0.1 12.9 2.7 0.3 0.0 2.1 95.6 0.4 5.1 24.4 1.0 3.6 0.0 28.2 0.0 7.4 1.1 1.7 34.1 0.4 5.4 0.0 0.2 2.8 0.1 3.4 13.9 2.8 2.0 0.2 100.1 140.5 21.6 129.7 2.5 37.2 1.0 11.3 66.4 32.3 0.8 8.1 195.4 58.1 159.2 33.0 0.4 43.2 29.8 34.2 4.6 37.9 37.2 18.3 9.9 20.6 13.2 14.5 24.1 19.6 12.2 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 46.4 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 102.6 4.7 0.0 0.0 0.0 0.0 0.0 0.0 37.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 150.0 0.7 0.0 0.0 0.0 RAD51AP2 FLJ17540 ENSG00000214842 "RAD51 associated protein 2" Q09MP3 2 17510584-17518439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 9.4" "Cell type enriched" "Detected in some" 8 "Spermatocytes: 457.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (3.87e-2)" "unprognostic (3.31e-2)" "unprognostic (9.98e-2)" "unprognostic (3.12e-2)" "unprognostic (4.61e-1)" "unprognostic (3.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.84e-3)" "unprognostic (2.64e-1)" "unprognostic (1.92e-1)" "unprognostic (1.71e-1)" "unprognostic (6.26e-3)" "unprognostic (3.82e-2)" "unprognostic (1.62e-3)" "unprognostic (1.15e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.6 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.7 0.2 0.5 1.5 0.9 1.2 0.1 0.7 2.8 0.9 0.0 0.2 0.0 2.1 0.0 0.0 6.0 0.0 0.0 12.8 0.0 0.1 0.2 0.0 0.0 8.0 0.0 0.0 0.2 2.0 0.0 0.0 0.1 0.0 1.7 0.1 0.0 4.1 0.7 0.0 0.0 0.2 5.7 0.9 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.1 0.4 0.1 1.1 0.0 0.1 0.2 0.2 26.3 0.1 0.4 457.6 51.7 0.6 0.6 0.0 0.0 0.5 1.6 0.9 VSNL1 "HLP3, HPCAL3, HUVISL1, VILIP, VILIP-1" ENSG00000163032 "Visinin like 1" P62760 2 17539126-17657018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 663.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 442.7;Inhibitory neurons: 243.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 663.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 125.9;Hep G2: 124.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053808 Approved Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA053808: AB_2682270" "unprognostic (1.04e-1)" "unprognostic (7.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (6.90e-4)" "unprognostic (4.90e-2)" "unprognostic (5.48e-2)" "unprognostic (2.81e-2)" "unprognostic (4.66e-2)" "unprognostic (2.99e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-1)" "unprognostic (5.14e-4)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.19e-3)" "unprognostic (1.51e-2)" 0.8 27.5 100.4 1.4 143.0 0.1 6.2 12.9 663.3 13.5 0.0 4.6 0.2 1.1 0.0 47.9 2.0 0.2 39.7 105.8 12.3 1.9 20.8 2.9 0.1 21.6 0.0 3.6 1.2 0.2 2.7 5.4 19.7 3.9 5.4 18.6 9.7 0.8 1.3 13.8 0.3 1.1 0.0 0.3 1.4 0.8 4.3 1.1 0.8 2.9 7.3 1.5 26.3 188.8 0.7 0.1 1.4 21.2 2.4 3.0 0.1 0.0 0.0 0.0 0.6 0.3 13.6 0.0 0.0 0.0 0.0 125.9 0.8 4.0 0.0 0.0 0.5 0.0 0.1 124.4 0.0 0.0 0.3 0.9 6.0 0.0 2.9 0.1 0.0 0.0 0.1 0.6 1.6 0.0 0.0 0.1 21.0 6.7 0.0 0.1 0.1 0.0 0.0 0.4 9.3 8.5 0.0 0.0 0.0 4.9 0.0 0.1 0.0 4.2 0.0 0.0 2.4 0.1 0.0 0.0 3.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.4 143.0 12.9 663.3 105.8 12.3 21.6 0.0 19.7 0.0 4.3 188.8 0.1 0.0 0.5 41.1 0.0 18.2 29.8 54.3 59.2 8.8 4.9 19.7 30.8 4.3 18.0 0.0 0.0 0.3 0.1 2.2 1.9 0.1 5.1 0.0 0.1 1.1 1.2 0.0 442.7 0.2 0.2 5.9 0.0 0.1 0.0 0.1 0.0 17.8 0.6 3.3 243.2 7.1 18.3 0.3 0.8 6.5 0.6 0.5 3.6 54.4 0.6 3.7 0.0 36.7 42.9 0.2 1.0 0.0 0.0 15.0 0.0 4.0 0.8 14.7 0.0 0.2 1.3 1.7 0.9 85.5 20.2 0.4 0.8 1.8 5.6 14.2 SMC6 "FLJ22116, SMC6L1" ENSG00000163029 "Structural maintenance of chromosomes 6" Q96SB8 2 17663812-17800242 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 153.4;Spermatocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035057, CAB037186, HPA042733" Uncertain Supported Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB037186: AB_1080031, HPA035057: AB_2674435, HPA042733: AB_2678134" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-2)" "unprognostic (1.33e-3)" "unprognostic (1.70e-2)" "unprognostic (6.57e-2)" "unprognostic (1.38e-2)" "unprognostic (3.91e-2)" "unprognostic (2.03e-2)" "unprognostic (2.94e-3)" "unprognostic (9.33e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.15e-4)" "unprognostic (7.02e-2)" "unprognostic (1.57e-1)" "unprognostic (1.25e-1)" "unprognostic (5.25e-2)" 8.4 5.2 6.8 14.7 7.6 13.3 8.5 11.4 7.7 9.5 31.9 11.9 9.0 9.4 17.4 13.2 8.7 9.4 8.6 8.0 8.4 8.9 17.2 9.0 21.6 6.2 6.9 6.9 6.1 6.0 11.6 14.2 7.4 6.7 13.3 6.8 12.4 10.8 9.4 14.7 11.4 8.7 5.3 14.9 9.8 35.2 8.4 14.3 7.7 8.8 22.6 8.6 11.4 10.6 50.6 24.8 31.9 26.6 33.6 32.2 32.2 26.4 18.6 16.7 16.2 27.9 19.4 43.9 16.6 24.2 27.9 34.4 38.5 31.0 25.7 52.3 25.2 60.3 16.2 42.1 31.3 42.3 31.2 24.3 21.4 27.0 35.1 20.5 38.9 26.4 67.5 35.4 31.9 20.8 32.8 21.7 43.3 25.3 19.7 38.7 90.0 29.9 16.2 27.7 28.0 29.9 38.4 20.0 30.0 35.1 12.7 18.7 42.7 41.3 16.5 32.5 47.2 25.0 43.5 87.9 21.0 45.7 30.0 2.2 3.8 8.2 7.8 4.2 6.6 24.8 6.0 7.1 5.1 26.4 4.3 6.0 3.1 7.5 6.7 27.7 14.4 4.1 6.8 7.6 11.4 7.7 8.0 8.4 6.2 6.9 7.4 5.3 8.4 10.6 25.6 48.1 12.5 34.9 63.7 18.2 21.6 41.5 68.3 15.2 8.4 9.3 36.5 14.3 30.8 5.5 12.5 15.2 51.5 18.9 11.7 17.0 153.4 33.0 26.3 21.9 11.3 36.6 51.1 11.7 27.5 21.0 32.1 18.2 20.8 38.6 15.7 19.3 17.6 6.7 47.9 15.7 16.2 10.0 9.1 123.7 22.4 20.1 26.6 30.0 22.0 12.5 25.7 56.3 60.5 19.7 17.2 27.4 25.3 25.1 16.0 14.5 27.2 17.4 46.0 41.2 67.8 150.0 87.9 37.4 14.2 12.4 22.2 28.9 21.2 14.9 GEN1 "FLJ40869, Gen" ENSG00000178295 "GEN1 Holliday junction 5' flap endonuclease" Q17RS7 2 17753858-17788946 "Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA020078, HPA021141" Enhanced Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA020078: AB_2670352, HPA021141: AB_2670599" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "unprognostic (1.52e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (8.64e-2)" "unprognostic (1.67e-3)" "unprognostic (7.90e-4)" "unprognostic (4.53e-2)" "unprognostic (1.70e-3)" "unprognostic (8.60e-3)" "unprognostic (8.04e-2)" "unprognostic (6.99e-2)" "unprognostic (1.89e-12)" "unprognostic (3.97e-3)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (1.49e-3)" 1.6 1.8 1.1 4.8 1.0 15.1 3.2 0.7 1.2 2.3 15.4 5.2 3.2 1.8 9.3 5.6 1.4 4.4 2.3 1.5 1.7 1.7 8.6 2.0 10.8 2.1 2.4 0.9 2.2 1.1 3.0 3.9 1.8 2.7 6.9 2.5 5.6 2.7 1.7 7.5 4.5 1.4 1.7 5.1 3.0 8.5 1.6 5.4 1.9 1.5 11.8 1.5 3.7 1.8 29.4 15.0 14.0 9.9 3.2 4.1 23.9 21.3 6.7 9.9 9.6 19.6 13.0 27.4 8.2 7.3 10.4 18.4 16.4 12.8 13.7 21.4 9.1 15.7 16.3 9.5 1.9 20.2 17.0 3.1 4.7 16.8 7.7 3.0 8.0 13.7 21.0 19.6 16.4 14.1 15.2 16.4 9.5 9.4 6.8 17.7 36.3 10.9 5.6 19.6 15.3 20.8 11.5 14.3 7.5 9.5 9.8 10.6 10.7 22.4 9.8 12.2 21.8 13.1 26.0 45.1 9.6 18.3 16.0 0.1 0.4 0.3 0.3 0.3 0.2 1.7 0.3 0.6 0.6 0.7 0.4 0.4 0.1 0.4 0.4 0.6 0.5 0.3 1.1 1.0 0.7 1.2 1.5 1.7 2.1 2.4 1.8 1.7 1.6 1.8 3.6 6.4 3.6 12.1 16.9 2.8 2.7 5.2 5.7 5.7 4.5 3.0 4.4 1.5 8.1 3.7 12.5 4.4 6.9 9.3 0.0 2.1 4.6 4.9 8.5 4.0 1.8 15.3 14.1 2.3 4.8 4.2 17.3 6.6 1.3 14.5 2.2 5.4 3.8 3.3 13.0 7.3 0.0 3.1 1.0 3.7 1.8 4.0 1.8 6.5 2.9 3.8 1.0 12.5 11.0 2.9 4.0 0.7 11.2 3.2 5.3 2.5 5.0 3.6 6.6 15.0 5.3 14.2 11.4 8.1 1.8 3.3 3.7 8.0 7.2 2.9 MSGN1 pMesogenin1 ENSG00000151379 "Mesogenin 1" A6NI15 2 17816460-17817798 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 26 "Basal squamous epithelial cells: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (3.63e-2)" "unprognostic (3.25e-2)" "unprognostic (1.66e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lung: 23.5;skeletal muscle: 86.0;tongue: 45.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Enteroendocrine cells: 32.5;Theca cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 69.2;RPMI-8226: 28.9;RT4: 48.2;U-266/84: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.9 1.1 2.6 3.8 2.9 0.0 6.2 3.9 4.0 7.8 9.5 12.5 3.7 3.2 2.6 6.0 3.9 5.4 6.6 2.9 4.2 5.0 3.8 23.5 0.6 10.5 7.9 1.0 9.8 2.9 1.2 11.0 12.5 6.5 5.0 0.4 11.2 3.1 86.0 5.6 5.4 3.3 5.3 1.0 9.5 3.9 4.3 1.4 2.3 45.5 2.0 6.8 6.3 4.4 8.5 1.4 0.7 0.0 1.6 0.8 3.8 2.8 8.5 1.7 2.0 0.1 17.1 0.0 0.9 3.0 1.9 2.7 20.7 0.1 1.8 0.0 5.7 0.0 0.2 0.1 8.1 0.2 0.7 0.7 12.9 0.1 1.2 15.5 0.4 3.9 0.4 0.0 1.0 2.2 0.0 0.0 10.2 11.5 0.2 2.4 69.2 28.9 1.8 48.2 20.3 0.7 0.0 5.3 6.1 4.8 2.8 0.0 0.2 2.7 0.0 0.2 21.6 0.1 34.9 0.1 15.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 3.9 4.0 2.9 4.2 10.5 7.9 12.5 5.3 4.3 4.4 3.8 28.9 8.2 0.0 0.0 13.9 16.8 6.9 21.1 0.2 11.5 7.0 0.5 18.6 6.8 11.0 0.0 0.6 0.0 10.9 0.0 21.5 0.3 0.9 0.6 5.9 32.5 0.0 0.3 0.4 3.5 12.1 8.2 0.9 1.3 4.3 2.5 5.4 0.5 0.0 16.9 5.6 14.2 0.0 4.5 1.2 1.5 0.4 21.4 1.9 0.7 0.1 0.0 7.1 2.5 2.4 4.9 3.8 1.2 13.6 4.1 5.5 1.7 0.2 6.6 13.5 10.6 0.3 3.4 8.0 5.8 0.8 0.6 30.6 10.3 7.1 RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA056686: AB_2683209, HPA078577: " "unprognostic (5.79e-2)" "unprognostic (3.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.03e-2)" "unprognostic (1.99e-2)" "unprognostic (8.71e-3)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (8.83e-3)" "unprognostic (6.41e-2)" "unprognostic (1.92e-1)" "unprognostic (1.82e-1)" "unprognostic (8.98e-2)" "unprognostic (1.58e-2)" "unprognostic (4.32e-2)" "unprognostic (3.69e-2)" 14.4 14.5 10.6 8.3 10.8 5.4 12.6 11.0 12.4 10.1 15.7 14.6 11.6 14.2 12.2 9.8 11.9 9.4 29.8 10.5 10.8 14.0 18.5 11.8 12.5 10.8 10.5 10.0 14.1 18.7 11.3 13.0 11.3 13.3 10.4 8.3 10.7 11.0 28.1 9.6 11.4 12.0 11.1 11.5 14.6 11.5 10.7 12.5 11.1 27.1 9.5 15.5 10.2 11.7 28.6 8.9 7.3 6.0 21.8 22.9 24.7 16.8 17.7 15.2 15.0 6.9 14.6 28.2 9.7 10.3 19.7 15.3 10.8 19.9 17.6 15.6 28.8 10.8 10.6 21.4 18.6 13.7 14.1 17.5 19.9 14.8 22.9 21.2 14.2 11.2 19.9 9.2 25.2 9.2 11.8 23.7 19.9 21.9 24.1 16.5 20.1 12.1 29.9 18.4 11.2 19.3 9.3 20.4 25.8 15.4 10.1 7.2 14.4 21.5 13.1 16.6 20.6 26.0 23.1 20.8 15.1 9.0 17.1 1.4 1.4 6.5 3.3 1.7 5.5 7.3 3.9 4.9 1.9 11.6 5.5 4.5 0.5 3.1 1.7 6.1 5.1 1.3 10.6 10.8 11.0 12.4 10.5 10.8 10.8 10.5 11.3 11.1 10.7 11.7 21.7 16.0 12.8 0.0 36.1 24.5 31.0 27.9 31.3 23.5 20.1 24.5 55.6 32.9 20.9 16.5 6.2 44.6 34.8 20.6 31.3 37.8 27.4 27.4 19.7 19.4 13.2 18.7 0.0 35.3 50.3 38.5 20.4 19.7 12.7 16.4 20.3 30.0 24.2 15.2 0.0 27.1 20.3 17.2 14.6 13.6 66.8 15.4 23.2 0.0 23.2 31.3 29.9 0.0 0.0 27.0 36.3 44.8 15.6 45.1 23.3 38.1 18.8 22.4 32.9 28.5 29.6 79.5 30.6 18.9 18.6 45.7 27.1 30.9 29.2 27.3 NT5C1B-RDH14 ENSG00000250741 "NT5C1B-RDH14 readthrough" 2 18555545-18589564 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 126 "testis: 16.6" "Group enriched" "Detected in some" 97 "Early spermatids: 52.3;Late spermatids: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 35.5" "Group enriched" "Detected in some" 29 "Early spermatids: 159.5;Late spermatids: 300.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.5 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.1 2.6 0.1 0.7 0.1 0.0 1.0 0.1 0.7 0.6 0.1 0.1 0.3 0.2 0.2 0.3 0.3 0.5 0.0 0.4 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.2 0.0 0.1 0.2 0.8 35.5 0.4 0.0 0.7 0.0 0.0 0.3 0.1 0.2 1.2 0.2 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 1.2 0.5 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.4 0.1 0.0 1.0 0.0 0.1 0.2 0.2 0.6 0.1 0.2 0.3 0.0 1.1 0.8 0.4 0.9 0.1 0.5 0.1 0.2 0.2 0.6 0.5 0.3 1.0 0.1 0.3 0.2 0.7 0.9 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.4 0.4 0.1 0.3 0.8 0.7 0.0 0.2 0.0 1.2 0.1 0.1 0.2 0.3 0.2 0.2 0.1 0.1 0.3 0.5 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 159.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 300.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSR1 ODD ENSG00000143867 "Odd-skipped related transcription factor 1" Q8TAX0 2 19351485-19358623 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 81.4" "Cell type enhanced" "Detected in some" "Fibroblasts: 35.8;Leydig cells: 133.6;Peritubular cells: 45.9;Smooth muscle cells: 21.4" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.9" "Region enhanced" "Detected in some" "thalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 11 "U-2197: 101.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015525 Uncertain NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA015525: AB_1854822" "unprognostic (1.71e-3)" "unprognostic (1.23e-1)" "unprognostic (6.85e-4)" "unprognostic (1.42e-1)" "unprognostic (1.39e-1)" "unprognostic (1.45e-2)" "unprognostic (8.47e-4)" "unprognostic (2.79e-1)" "unprognostic (1.91e-1)" "unprognostic (6.87e-2)" "unprognostic (3.56e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-3)" "unprognostic (1.89e-1)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" 38.6 2.4 0.4 3.5 0.8 0.0 22.4 0.3 1.7 16.7 1.8 23.1 1.4 10.3 0.3 3.6 8.1 5.9 13.4 1.6 0.0 1.5 0.5 17.0 0.5 0.3 0.1 6.1 2.8 0.2 2.7 3.3 0.2 13.9 2.0 0.0 31.5 3.7 3.0 10.8 11.1 11.3 0.2 0.1 9.7 5.4 3.4 0.6 10.2 3.5 0.1 81.4 12.3 0.0 0.0 2.4 0.1 4.7 3.2 9.2 0.0 6.0 2.8 5.6 2.8 0.0 0.1 0.0 0.0 8.5 2.7 0.0 3.0 1.4 1.4 0.0 0.2 0.0 0.1 3.5 4.0 0.0 0.2 4.6 0.0 5.2 6.9 4.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.1 0.0 3.6 5.0 0.0 0.2 0.0 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 1.3 0.4 101.8 0.2 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.3 1.7 1.6 0.0 0.3 0.1 0.2 0.2 3.4 0.0 1.2 0.0 0.5 0.0 0.0 4.7 1.0 1.7 0.6 0.0 1.0 6.1 7.2 0.0 1.1 3.7 0.0 0.5 0.1 0.1 0.0 1.3 0.7 0.0 0.7 0.5 0.0 0.0 0.1 0.0 0.4 35.8 0.0 0.1 1.3 1.2 0.0 0.0 0.9 0.0 0.0 0.3 4.1 0.0 4.9 3.8 133.6 0.3 3.6 2.8 0.0 0.0 0.0 0.0 0.1 0.4 0.1 45.9 0.0 0.4 0.0 2.9 0.3 0.0 0.0 1.3 21.4 0.4 0.1 0.3 4.1 0.4 0.7 0.8 0.2 1.1 TTC32 ENSG00000183891 "Tetratricopeptide repeat domain 32" Q5I0X7 2 19896631-19901983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036024 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria Nucleoplasm "HPA036024: AB_10673493" "unprognostic (2.77e-3)" "unprognostic (5.44e-2)" "unprognostic (8.85e-2)" "unprognostic (8.80e-3)" "unprognostic (1.08e-1)" "unprognostic (2.62e-1)" "unprognostic (5.25e-2)" "prognostic favorable (9.44e-4)" "unprognostic (4.46e-2)" "unprognostic (1.48e-2)" "unprognostic (4.92e-3)" "unprognostic (6.22e-2)" "prognostic unfavorable (5.45e-6)" "unprognostic (1.21e-1)" "unprognostic (1.40e-1)" "unprognostic (1.72e-2)" "unprognostic (2.27e-2)" 11.8 8.8 8.7 12.3 10.5 34.7 16.6 13.6 17.2 12.3 8.6 11.7 12.2 13.9 26.0 7.4 11.9 6.7 7.1 8.8 9.1 11.4 12.3 10.0 15.5 10.6 10.0 16.5 8.6 8.2 11.3 8.5 11.3 16.0 10.2 33.0 11.1 9.3 22.5 13.8 13.1 8.0 9.5 15.6 11.4 12.5 9.7 19.7 12.4 7.7 10.1 11.3 11.2 14.2 22.5 14.4 12.8 9.6 5.6 12.3 2.7 4.8 8.0 7.7 5.0 7.3 25.6 14.5 2.7 5.1 9.6 14.6 5.6 15.4 4.9 21.3 23.3 14.8 20.4 12.8 12.1 14.2 25.5 11.7 9.6 8.6 20.4 6.5 7.5 23.3 27.1 28.5 6.4 6.8 10.7 21.7 9.6 8.4 24.1 12.6 8.5 24.1 21.6 8.6 20.6 19.1 16.1 8.5 18.2 14.1 11.9 5.5 5.6 11.6 12.4 11.5 6.6 29.8 27.3 24.0 17.9 13.9 6.7 9.2 7.6 23.1 7.3 5.7 8.7 12.2 11.6 7.8 7.2 11.9 15.8 12.2 28.0 6.7 6.9 5.0 15.6 4.9 8.7 10.5 13.6 17.2 8.8 9.1 10.6 10.0 11.3 9.5 9.7 14.2 23.2 9.6 14.4 8.5 24.7 18.9 33.4 36.0 34.7 66.9 27.4 39.0 15.8 15.7 26.4 12.9 14.6 14.6 13.7 10.0 45.0 12.2 27.2 25.8 6.1 16.2 28.3 34.0 7.1 24.8 8.7 19.6 14.8 13.2 8.8 7.2 7.5 24.1 9.1 42.1 8.6 19.9 32.6 8.8 8.9 7.2 19.9 17.4 7.2 5.6 14.6 67.8 11.3 9.5 22.0 14.6 12.9 9.8 12.3 15.8 13.7 28.5 48.7 39.2 13.1 21.1 21.3 113.2 38.7 22.4 26.1 9.6 21.6 9.0 11.7 26.7 WDR35 "FAP118, IFT121, IFTA1, KIAA1336, MGC33196" ENSG00000118965 "WD repeat domain 35" Q9P2L0 2 19910263-19990105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 36.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044147 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA044147: AB_10970242" "unprognostic (2.51e-1)" "unprognostic (4.93e-2)" "unprognostic (9.13e-2)" "unprognostic (4.01e-2)" "unprognostic (3.66e-2)" "unprognostic (2.79e-1)" "unprognostic (2.94e-3)" "unprognostic (3.08e-2)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-2)" "unprognostic (3.68e-2)" "unprognostic (6.98e-2)" "unprognostic (2.17e-2)" "unprognostic (5.03e-2)" "unprognostic (1.02e-1)" "unprognostic (2.71e-1)" 3.6 5.1 4.3 2.7 4.4 2.0 7.8 4.1 4.7 6.6 10.0 4.9 1.7 9.3 7.2 2.9 11.3 3.5 3.3 4.1 5.5 7.9 2.0 4.5 2.7 5.5 5.5 9.6 3.8 14.4 9.0 2.7 5.1 5.5 3.0 12.6 3.0 6.3 2.5 3.4 3.0 6.2 4.9 2.0 3.7 10.6 6.0 4.8 8.8 2.6 2.6 4.4 3.7 5.7 8.3 10.4 9.9 9.5 7.6 7.4 0.5 4.2 7.4 6.0 4.3 3.2 3.6 0.0 1.8 4.7 5.0 2.6 10.6 10.3 9.9 1.6 8.2 8.1 6.6 10.0 6.6 15.8 3.1 9.0 7.2 10.7 15.2 10.8 7.4 3.3 13.1 2.3 6.1 3.0 2.3 11.4 11.9 1.5 10.0 0.0 7.1 3.5 12.8 4.7 18.6 21.9 6.9 4.6 12.3 4.7 4.9 3.4 7.7 6.8 3.3 9.4 12.4 4.7 8.3 0.0 12.7 1.1 6.8 2.9 0.1 0.3 0.5 0.0 0.1 0.4 0.3 0.3 0.2 0.6 0.3 0.4 0.2 0.4 0.0 0.1 0.4 0.2 4.3 4.4 4.1 4.7 4.1 5.5 5.5 5.5 5.1 4.9 6.0 5.7 2.9 3.2 9.0 36.6 5.7 3.3 3.5 5.0 2.2 6.5 5.8 7.2 10.8 11.5 7.2 11.0 2.1 0.2 2.9 0.3 0.0 3.3 1.9 16.1 13.1 3.1 6.0 7.8 30.0 4.0 1.0 9.7 5.1 4.0 9.5 9.4 3.6 2.4 1.3 6.7 21.9 1.5 4.1 0.9 2.8 3.5 10.2 2.0 3.6 18.7 1.1 10.0 2.1 25.1 27.6 6.3 0.7 10.9 2.4 2.0 0.7 5.6 28.6 15.2 6.6 14.6 7.4 28.8 9.0 2.2 2.6 0.3 5.4 9.0 1.5 1.1 MATN3 "EDM5, HOA" ENSG00000132031 "Matrilin 3" O15232 2 19992052-20012668 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 13.2;placenta: 11.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 38.5;Sertoli cells: 26.3" "Cancer enhanced" "Detected in all" "pancreatic cancer: 13.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "Hep G2: 143.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 1.7" HPA051250 Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" NA NA 440000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum, Golgi apparatus" "HPA051250: AB_2681406" "unprognostic (3.47e-1)" "prognostic unfavorable (1.41e-4)" "unprognostic (7.57e-2)" "unprognostic (2.75e-2)" "unprognostic (1.71e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (8.62e-5)" "unprognostic (1.27e-1)" "unprognostic (4.84e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (2.54e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.51e-1)" "unprognostic (7.04e-2)" "unprognostic (3.15e-2)" 2.2 0.6 5.1 0.5 3.2 0.0 2.7 3.4 5.7 2.5 2.5 0.6 0.4 2.1 0.9 0.5 1.9 2.1 0.4 3.4 3.9 1.9 0.0 13.2 0.3 5.2 6.0 0.7 0.4 0.4 0.3 11.3 5.2 1.6 0.5 0.3 0.6 4.6 0.3 0.8 0.4 1.7 4.7 0.3 1.8 0.9 7.6 0.1 1.3 0.6 0.3 0.8 1.2 3.6 6.4 4.9 16.1 0.1 4.5 9.7 1.0 2.0 1.1 6.5 8.2 4.7 2.7 0.0 0.8 1.7 6.2 1.1 0.4 12.7 9.2 0.0 0.4 0.0 1.1 143.4 1.1 0.0 0.0 21.3 0.7 7.1 1.7 4.5 8.7 0.0 0.0 0.0 13.8 2.5 0.0 0.0 5.0 0.2 2.4 0.0 0.0 0.0 19.5 4.5 0.1 2.1 10.6 1.8 6.5 27.1 19.2 0.1 4.9 9.5 11.4 0.4 1.2 0.1 0.0 0.0 1.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.2 3.4 5.7 3.4 3.9 5.2 6.0 5.2 4.7 7.6 3.6 1.6 38.5 2.2 0.0 0.0 0.3 0.3 2.6 0.0 0.0 5.4 1.3 0.3 0.0 2.3 1.8 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.3 0.8 2.8 0.0 0.0 0.1 0.2 1.9 1.9 0.0 0.5 0.0 4.4 0.0 0.0 0.1 0.0 0.2 0.0 4.1 0.0 0.3 0.4 1.5 0.1 3.6 4.7 0.0 0.0 0.0 0.5 0.2 1.1 0.0 4.5 0.0 0.3 0.0 0.8 1.6 0.0 26.3 0.8 6.8 0.0 1.3 0.0 0.1 0.1 0.1 6.3 0.0 0.2 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 SDC1 "CD138, SDC, SYND1, syndecan" ENSG00000115884 "Syndecan 1" P18827 2 20200797-20225433 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 491.6;liver: 484.7;skin 1: 447.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 267.4;Hepatocytes: 603.1;Squamous epithelial cells: 246.6;Syncytiotrophoblasts: 250.8;Urothelial cells: 492.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 7 "midbrain: 17.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 482.2;hTCEpi: 436.6;U-251 MG: 470.0;U-266/70: 467.4;U-266/84: 1069.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "CAB002424, HPA006185, HPA067477" Enhanced Approved "Focal adhesion sites" "Secreted to blood" NA NA 63100000 3100000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 22: Epithelial cell types - Mixed function" "Focal adhesion sites" "CAB002424: AB_442050, HPA006185: AB_1857705, HPA067477: " "prognostic unfavorable (2.22e-4)" "unprognostic (6.80e-3)" "unprognostic (6.80e-2)" "unprognostic (7.84e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (4.02e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (3.66e-1)" "unprognostic (2.27e-3)" "unprognostic (1.79e-1)" "unprognostic (1.63e-1)" "unprognostic (1.94e-2)" "unprognostic (4.27e-1)" "unprognostic (1.62e-2)" "unprognostic (1.52e-1)" 2.4 17.4 0.7 17.2 0.2 1.2 23.8 2.3 0.8 127.2 0.7 61.8 75.8 2.2 19.9 491.6 10.5 77.1 0.6 0.3 2.0 99.5 484.7 59.6 7.3 0.6 17.3 1.6 16.6 5.4 2.0 32.6 0.8 56.3 33.3 0.7 85.8 25.9 1.6 447.4 53.6 2.2 0.2 20.1 87.3 3.3 2.5 5.1 18.3 0.0 43.2 104.8 242.1 0.1 252.6 137.6 42.7 108.1 11.6 1.6 134.9 68.7 65.4 62.7 52.8 29.5 148.9 0.3 24.8 48.8 34.8 241.4 19.0 482.2 41.8 1.3 12.5 0.0 12.2 150.2 10.3 11.0 1.0 6.4 436.6 56.5 132.9 87.2 6.9 0.0 6.4 94.7 34.0 149.6 0.6 2.6 38.7 189.6 263.1 5.3 15.7 189.9 80.5 370.0 12.4 99.7 51.9 342.4 15.2 17.1 34.5 2.8 10.7 246.9 78.6 9.2 470.0 467.4 1069.8 1.0 74.5 0.6 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.2 2.3 0.8 0.3 2.0 0.6 17.3 0.8 0.2 2.5 0.1 0.4 93.0 99.0 0.0 33.0 113.9 189.1 162.8 81.4 0.6 29.9 26.7 0.9 267.4 161.8 42.3 0.0 3.8 0.7 147.2 31.3 61.3 0.1 16.6 5.0 3.5 10.8 13.5 0.3 21.8 46.3 5.0 55.0 22.9 6.3 7.5 7.5 603.1 2.3 21.9 0.2 73.1 50.8 10.6 11.9 0.3 0.6 2.5 21.4 0.0 0.6 0.3 0.0 1.0 0.0 111.4 78.0 1.2 165.1 78.0 106.5 88.5 43.4 0.4 0.0 0.1 15.0 1.0 14.0 246.6 229.0 250.8 4.0 0.1 85.1 492.8 PUM2 "KIAA0235, PUMH2" ENSG00000055917 "Pumilio RNA binding family member 2" Q8TB72 2 20248691-20352234 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030316, HPA049670" Approved Enhanced Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "HPA030316: AB_10610289, HPA049670: AB_2680845" "unprognostic (2.41e-1)" "unprognostic (8.77e-2)" "unprognostic (1.97e-1)" "unprognostic (2.31e-2)" "unprognostic (9.89e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (3.86e-2)" "unprognostic (1.23e-1)" "unprognostic (4.49e-3)" "unprognostic (1.05e-2)" "unprognostic (6.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.09e-1)" "unprognostic (2.41e-1)" "unprognostic (4.81e-2)" "unprognostic (2.87e-2)" 27.6 29.8 29.7 33.4 31.7 33.4 41.7 42.5 32.7 36.2 32.4 36.5 34.4 36.3 32.8 39.2 29.7 27.1 33.1 31.1 30.9 36.8 43.1 33.2 48.6 26.0 29.3 44.6 27.4 41.4 8.3 40.3 26.1 37.3 37.0 66.8 33.0 33.1 21.5 47.2 35.6 32.3 29.1 42.6 35.8 24.9 31.6 70.5 57.6 32.6 47.6 38.0 18.3 37.6 72.4 50.0 65.3 46.1 40.2 40.5 65.9 49.2 53.6 48.4 42.2 43.5 33.0 96.3 11.0 44.9 58.2 38.9 61.4 35.6 71.2 87.0 38.2 105.0 35.3 62.2 43.4 107.2 93.3 29.7 79.7 42.1 77.4 45.5 53.1 57.1 75.0 82.9 57.3 35.5 93.6 65.9 55.8 68.3 31.5 80.6 110.9 73.8 45.0 68.1 55.9 76.6 42.2 58.3 48.1 43.4 33.0 61.5 52.5 58.6 58.5 38.3 64.6 93.3 123.0 181.8 35.3 75.8 51.4 11.5 4.0 5.8 6.0 5.2 7.1 4.8 6.7 7.5 4.2 5.3 7.3 6.0 11.6 7.7 7.3 3.7 5.8 3.7 29.7 31.7 42.5 32.7 31.1 30.9 26.0 29.3 26.1 29.1 31.6 37.6 43.6 35.3 51.6 89.5 57.6 79.7 32.2 26.4 74.0 94.6 46.9 30.5 46.5 32.9 33.8 47.8 62.6 36.3 43.6 44.0 11.7 16.6 10.1 33.9 35.6 45.0 34.6 41.0 134.7 15.5 16.9 36.5 43.8 45.9 20.3 53.0 41.4 56.3 29.1 58.9 153.5 43.2 38.7 70.7 44.2 5.8 34.2 44.9 32.0 144.3 42.7 26.8 43.3 155.3 186.0 22.6 28.1 26.4 54.7 57.8 33.9 29.7 39.5 72.3 32.9 40.5 47.6 16.8 16.6 75.2 106.3 52.0 50.1 31.2 40.2 56.6 RHOB "ARH6, ARHB, MST081, RHOH6" ENSG00000143878 "Ras homolog family member B" P62745 2 20447074-20449440 "Cancer-related genes, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Protein transport, Transport" "Developmental protein" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1272.8;Basal squamous epithelial cells: 1327.7;Hepatocytes: 1360.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 5.6;eosinophil: 18.0;intermediate monocyte: 11.4;neutrophil: 21.5;non-classical monocyte: 13.3" "Group enriched" "Detected in many" 13 "granulocytes: 21.5;monocytes: 13.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 297.9;RPTEC TERT1: 462.9;SK-BR-3: 561.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (9.66e-3)" "unprognostic (5.57e-3)" "unprognostic (8.29e-2)" "unprognostic (6.48e-2)" "unprognostic (2.85e-1)" "unprognostic (9.16e-3)" "unprognostic (5.41e-3)" "unprognostic (4.91e-2)" "unprognostic (1.04e-2)" "unprognostic (3.22e-2)" "unprognostic (3.29e-1)" "unprognostic (2.13e-2)" "prognostic favorable (4.23e-4)" "unprognostic (5.71e-2)" "unprognostic (2.56e-1)" "unprognostic (3.01e-2)" "unprognostic (2.49e-2)" 592.1 538.8 216.9 94.7 331.1 71.9 459.9 309.1 207.4 495.7 106.2 657.1 40.4 370.7 67.0 166.4 599.0 166.4 354.7 181.8 260.8 173.7 642.3 386.6 43.7 356.0 315.0 437.3 111.5 34.4 135.2 170.3 317.1 342.9 81.0 27.5 136.0 219.7 366.7 391.8 203.4 260.8 328.1 115.7 438.5 52.9 286.8 52.4 171.1 153.4 13.1 490.0 353.6 356.2 29.0 42.5 79.9 19.4 202.3 48.1 112.7 133.5 48.2 58.0 19.6 27.2 32.9 0.1 13.8 68.2 113.8 16.4 1.3 27.4 20.5 33.5 86.8 1.5 118.4 224.4 52.7 0.4 86.0 88.7 93.3 34.6 45.5 55.8 297.9 0.2 8.6 51.1 35.6 78.0 1.4 10.9 35.4 45.3 17.7 7.5 35.8 52.4 462.9 66.6 64.7 39.7 27.9 561.2 81.7 224.2 98.6 7.3 178.8 25.8 61.2 10.8 51.7 96.4 15.3 0.5 6.6 0.4 24.3 5.6 2.5 18.0 0.6 11.4 0.1 0.2 0.0 0.4 1.3 0.2 0.0 0.1 21.5 0.9 13.3 0.1 0.1 1.1 216.9 331.1 309.1 207.4 181.8 260.8 356.0 315.0 317.1 328.1 286.8 356.2 1272.8 48.1 101.9 238.3 118.7 73.9 281.4 53.0 1327.7 20.4 465.1 460.4 118.6 700.6 70.6 77.3 2.1 114.2 66.8 655.2 64.6 296.4 6.0 346.3 283.8 409.6 561.2 33.7 17.3 119.9 134.5 621.3 670.7 364.6 24.7 390.9 376.6 1360.8 190.1 33.7 18.2 496.4 73.2 418.1 136.4 20.9 270.6 473.4 96.0 43.1 31.6 344.8 5.2 32.6 91.9 200.8 318.8 197.5 191.6 212.1 203.1 289.0 89.1 19.3 927.0 542.5 800.5 6.5 22.5 701.2 90.5 270.1 62.5 244.6 340.7 85.2 HS1BP3 HS1-BP3,FLJ14249 ENSG00000118960 "HCLS1 binding protein 3" Q53T59 2 20560448-20651130 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 42.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035050 Approved Approved Nucleoli,Cytosol No No 54000 "Cluster 18: Basophils - Vesicular transport" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoli Cytosol "HPA035050: AB_10601816" "unprognostic (4.52e-2)" "unprognostic (5.93e-2)" "unprognostic (2.67e-1)" "unprognostic (4.39e-1)" "unprognostic (4.61e-2)" "unprognostic (1.45e-3)" "prognostic unfavorable (2.97e-5)" "unprognostic (2.06e-3)" "unprognostic (1.88e-2)" "unprognostic (2.16e-1)" "unprognostic (9.53e-2)" "unprognostic (8.00e-2)" "prognostic favorable (2.30e-4)" "unprognostic (1.80e-1)" "unprognostic (1.19e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-1)" 18.5 31.0 16.4 10.0 20.6 13.7 15.9 17.9 19.6 21.5 19.4 33.6 13.1 22.2 13.3 18.6 19.4 16.4 23.3 16.9 17.5 24.8 57.4 18.5 9.2 20.4 19.3 17.5 14.5 13.1 16.3 15.5 19.4 26.7 12.6 3.7 16.7 17.5 13.0 23.3 17.7 21.1 15.8 18.4 22.0 13.8 21.3 7.4 17.8 10.1 7.6 29.2 17.8 23.3 20.3 23.1 11.5 14.1 58.8 39.2 22.7 7.6 34.9 17.7 23.0 18.2 24.0 13.5 5.9 11.1 80.1 12.5 23.1 24.0 8.6 17.4 19.1 7.2 11.3 61.2 54.8 5.5 30.5 42.1 53.8 20.0 36.5 20.7 34.1 11.9 4.7 28.3 20.5 17.4 2.5 9.3 9.6 29.9 16.4 13.3 23.3 13.4 39.0 24.4 10.9 16.7 5.4 23.4 45.0 23.2 14.6 11.2 21.7 17.3 18.5 27.0 11.7 19.9 24.5 12.9 37.3 25.8 18.7 17.9 14.7 14.5 6.0 13.9 4.2 6.8 3.6 4.7 9.9 4.3 3.0 3.3 17.7 3.8 18.3 3.6 3.4 8.6 16.4 20.6 17.9 19.6 16.9 17.5 20.4 19.3 19.4 15.8 21.3 23.3 17.6 6.4 17.9 3.3 8.2 4.5 7.4 5.6 2.2 4.0 6.2 8.0 6.2 8.6 10.9 7.3 0.0 9.8 6.5 12.5 17.6 21.4 20.8 9.3 9.4 8.4 6.7 7.0 2.6 14.9 17.8 9.7 8.2 12.5 2.5 8.5 11.0 9.2 30.7 15.2 2.5 7.3 12.2 20.1 5.5 42.7 8.4 13.9 14.2 4.7 13.1 8.9 15.5 3.0 5.4 9.7 11.9 10.5 4.9 5.2 21.6 28.2 10.4 5.3 0.0 7.1 17.1 16.7 10.5 5.8 5.3 17.5 6.3 7.8 7.7 4.5 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 LDAH "C2orf43, FLJ21820" ENSG00000118961 "Lipid droplet associated hydrolase" Q9H6V9 2 20684014-20823130 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034729, HPA034730" Approved NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA034729: AB_10603684, HPA034730: AB_2674304" "unprognostic (1.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.52e-3)" "unprognostic (1.36e-1)" "unprognostic (2.21e-2)" "unprognostic (6.34e-2)" "prognostic unfavorable (6.09e-6)" "unprognostic (3.57e-2)" "unprognostic (1.36e-1)" "unprognostic (1.27e-2)" "unprognostic (6.45e-2)" "unprognostic (2.44e-1)" "prognostic favorable (1.18e-4)" "unprognostic (1.05e-1)" "unprognostic (2.31e-1)" "unprognostic (2.22e-1)" "unprognostic (3.97e-2)" 7.3 14.1 5.1 7.3 6.8 5.0 7.6 4.8 5.6 7.9 6.8 10.8 7.4 7.3 9.3 8.0 6.2 6.8 4.3 5.3 6.4 16.8 12.1 5.5 11.1 5.7 5.1 8.0 7.4 9.4 5.8 8.7 5.8 7.0 11.7 8.3 6.9 6.2 1.2 6.1 6.5 8.1 5.9 9.0 7.8 5.0 6.0 11.7 8.2 1.7 13.4 9.7 6.0 7.7 20.2 18.3 45.6 0.0 18.6 24.6 28.5 17.9 12.2 14.5 11.1 19.8 12.3 25.3 0.0 13.1 25.4 16.9 34.8 12.9 14.9 31.6 17.2 37.1 16.6 30.5 19.0 28.2 8.9 20.9 18.9 14.0 3.6 19.7 27.7 33.8 49.7 18.6 25.5 13.0 41.1 19.4 29.1 41.7 0.0 33.1 36.6 28.8 29.0 29.4 25.0 37.9 11.8 18.7 19.9 37.9 15.9 19.7 25.6 13.0 6.6 17.0 10.7 22.7 45.2 11.6 25.3 26.8 24.6 0.9 3.2 0.3 6.6 4.9 4.3 7.8 6.5 5.6 5.8 5.5 5.9 5.9 0.2 5.5 3.9 5.4 6.1 4.2 5.1 6.8 4.8 5.6 5.3 6.4 5.7 5.1 5.8 5.9 6.0 7.7 5.0 16.0 10.6 0.0 9.3 0.0 3.4 0.0 5.7 9.3 5.3 3.9 2.8 7.2 4.3 7.3 16.7 12.0 4.6 3.4 7.9 7.4 8.7 4.2 10.9 6.3 3.6 13.3 0.0 6.4 11.6 5.1 9.7 6.1 6.3 14.8 8.6 7.9 9.0 11.8 0.0 6.0 0.0 9.8 0.0 2.7 7.5 5.5 0.0 0.0 4.7 15.0 5.2 0.0 0.0 6.5 5.5 6.8 9.9 3.7 5.0 12.0 0.0 9.6 6.6 4.2 5.4 4.3 5.2 7.7 0.0 11.5 6.7 15.8 6.1 3.6 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 TDRD15 ENSG00000218819 "Tudor domain containing 15" B5MCY1 2 21123968-21144368 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 5.4" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Late spermatids: 12.1;Sertoli cells: 6.6;Spermatocytes: 34.5;Spermatogonia: 8.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.5;U-266/70: 7.5;U-266/84: 3.0" "HPA051770, HPA054675" Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA051770: AB_2681601, HPA054675: AB_2682569" "unprognostic (4.20e-3)" "unprognostic (1.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 2.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 12.1 0.6 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.0 34.5 8.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 KLHL29 "KBTBD9, KIAA1921" ENSG00000119771 "Kelch like family member 29" Q96CT2 2 23385179-23708611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Excitatory neurons: 146.4;Inhibitory neurons: 132.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 16.9;RH-30: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049057, HPA057379" Approved Approved Mitochondria,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Cytosol "HPA049057: AB_2680615, HPA057379: AB_2683422" "unprognostic (8.08e-3)" "unprognostic (2.91e-1)" "unprognostic (7.43e-3)" "unprognostic (2.65e-2)" "unprognostic (9.11e-2)" "unprognostic (1.67e-2)" "unprognostic (3.54e-3)" "unprognostic (1.16e-1)" "unprognostic (4.71e-2)" "unprognostic (2.18e-1)" "prognostic favorable (2.19e-4)" "unprognostic (2.53e-1)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.12e-2)" "unprognostic (9.06e-2)" "unprognostic (7.44e-2)" "unprognostic (5.25e-4)" 6.6 9.2 3.9 2.2 4.0 0.1 5.8 0.7 8.9 5.3 3.4 8.8 0.9 6.1 1.2 2.9 4.4 3.1 2.5 5.2 3.3 4.2 2.6 3.9 2.6 2.0 2.6 2.5 1.9 2.3 10.2 3.3 2.5 7.7 1.2 7.0 3.0 4.8 10.7 5.7 3.8 3.0 3.0 5.0 3.9 0.9 3.4 1.6 1.6 2.9 1.6 4.4 5.1 4.5 1.4 1.1 7.5 3.8 7.0 4.6 12.9 7.8 6.0 3.1 2.2 0.0 0.4 5.1 2.6 3.0 16.9 0.2 1.7 6.7 2.1 0.0 8.0 0.0 6.7 0.0 2.4 0.0 9.9 3.4 8.9 4.1 11.6 1.0 5.3 0.2 0.0 0.0 1.7 0.7 1.8 0.0 3.7 0.0 2.3 0.5 19.3 0.1 5.8 2.3 11.3 2.3 1.0 0.8 4.5 3.0 0.0 0.1 5.4 3.1 14.4 6.7 2.7 0.2 0.0 0.0 11.8 0.5 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 4.0 0.7 8.9 5.2 3.3 2.0 2.6 2.5 3.0 3.4 4.5 1.2 6.4 5.3 6.8 0.3 4.7 10.4 2.9 7.4 8.4 0.4 6.0 2.3 4.3 1.3 1.8 27.1 1.2 0.1 0.1 0.0 1.2 1.8 3.5 5.4 2.3 4.2 0.0 146.4 0.2 0.9 3.9 0.0 3.9 0.0 0.2 0.7 0.5 0.3 1.7 132.7 0.7 0.0 0.0 0.0 0.7 5.0 0.4 1.8 7.5 0.0 1.7 0.0 5.5 4.7 0.4 0.4 4.1 0.0 1.9 0.0 1.3 1.7 26.1 6.6 6.5 6.5 0.1 1.1 2.0 5.8 0.8 0.4 0.4 0.8 1.5 ATAD2B KIAA1240 ENSG00000119778 "ATPase family AAA domain containing 2B" Q9ULI0 2 23748664-23927123 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 93.0;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 143.7;Oligodendrocytes: 125.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034555 Uncertain Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA034555: AB_10601665" "unprognostic (2.40e-1)" "unprognostic (4.36e-2)" "unprognostic (2.58e-1)" "unprognostic (2.16e-1)" "unprognostic (1.62e-2)" "unprognostic (5.93e-3)" "unprognostic (5.57e-3)" "unprognostic (2.22e-2)" "unprognostic (1.85e-2)" "unprognostic (1.23e-1)" "unprognostic (9.14e-2)" "unprognostic (7.56e-3)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.46e-1)" "unprognostic (2.68e-1)" "unprognostic (2.67e-2)" "unprognostic (1.98e-1)" 4.8 3.1 4.9 5.9 6.1 9.8 4.5 8.1 5.5 5.9 11.0 4.2 5.1 4.9 2.6 6.0 4.6 3.5 3.7 4.0 6.1 3.7 4.1 4.8 7.3 6.5 5.7 5.8 4.3 3.3 4.1 4.0 5.7 4.3 4.3 9.4 4.8 2.3 4.4 8.3 5.2 2.8 4.8 5.1 3.9 4.3 5.9 10.3 5.2 2.8 6.5 4.0 6.6 7.7 4.1 3.4 11.0 5.0 3.1 3.4 8.5 2.7 2.2 3.5 2.4 5.5 2.0 13.4 2.4 2.5 1.6 5.3 8.6 3.0 2.9 8.8 4.1 11.3 4.5 6.6 3.4 10.2 8.1 2.7 5.2 2.1 3.4 2.9 4.8 7.4 12.2 5.8 2.7 7.0 9.5 11.9 6.5 6.8 1.9 10.8 11.8 3.1 3.8 9.1 5.1 8.4 7.4 9.0 4.2 6.0 4.4 10.0 4.6 3.5 4.0 3.0 3.2 6.0 2.9 10.0 1.9 11.5 3.3 15.8 7.9 5.1 3.9 4.7 4.4 8.5 3.6 3.5 7.6 6.4 5.2 4.2 12.0 6.0 6.2 11.0 3.4 1.8 4.9 6.1 8.1 5.5 4.0 6.1 6.5 5.7 5.7 4.8 5.9 7.7 18.4 3.2 16.0 93.0 26.1 10.7 7.7 6.4 13.1 27.6 9.5 7.1 11.3 10.0 12.2 9.2 47.9 8.4 33.8 15.2 0.0 7.7 60.2 10.1 20.1 14.6 15.6 11.1 60.3 12.2 7.4 14.7 19.9 17.0 13.3 21.2 11.7 10.7 8.2 10.1 95.5 11.0 10.2 14.4 17.6 36.1 12.5 23.8 3.6 85.3 30.9 13.0 22.6 143.7 125.3 8.9 18.6 10.9 14.0 10.8 17.2 2.4 8.5 45.4 6.6 19.1 13.5 23.5 16.8 20.0 17.5 10.9 22.6 13.1 11.3 16.5 UBXN2A UBXD4 ENSG00000173960 "UBX domain protein 2A" P68543 2 23927285-24004909 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065482, HPA069096" Supported Approved Centrosome NA NA "Cluster 6: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 51: Myeloid cells - Hemostasis" Centrosome "HPA065482: AB_2685495, HPA069096: AB_2686084" "unprognostic (5.29e-2)" "unprognostic (1.93e-1)" "unprognostic (1.43e-2)" "unprognostic (9.01e-2)" "unprognostic (1.14e-1)" "unprognostic (8.86e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (9.26e-2)" "unprognostic (2.76e-1)" "unprognostic (1.15e-2)" "unprognostic (1.28e-2)" "unprognostic (1.04e-1)" "unprognostic (2.18e-1)" "unprognostic (8.85e-2)" "unprognostic (2.14e-1)" "unprognostic (4.60e-2)" "unprognostic (6.75e-2)" 6.1 3.7 3.5 3.4 4.1 5.0 5.0 5.9 3.6 3.1 2.6 4.9 5.7 5.1 3.9 5.1 3.5 3.7 7.8 2.9 3.9 4.1 5.7 4.6 3.9 4.2 4.5 3.9 3.0 7.4 1.5 5.3 4.2 3.8 4.1 5.6 4.5 4.7 10.9 4.8 5.4 6.9 3.9 3.0 2.9 3.2 3.9 4.5 3.9 7.9 4.3 4.0 2.4 5.8 14.8 9.6 13.1 8.8 14.8 12.9 6.6 14.8 9.9 14.1 9.8 7.2 6.5 12.7 4.5 9.5 9.9 6.2 12.7 10.5 12.5 25.7 12.0 14.9 6.4 10.9 10.9 9.5 6.4 15.8 8.3 12.4 9.4 10.0 8.5 9.6 17.0 12.3 12.4 11.2 12.6 6.0 10.4 9.5 6.8 16.9 32.7 5.6 5.9 11.3 6.5 15.6 14.2 6.9 18.6 9.2 4.1 5.3 14.2 10.1 10.5 9.3 9.6 17.7 20.3 18.0 7.9 8.7 10.4 4.8 2.1 2.5 3.2 1.2 3.5 3.7 3.3 3.1 1.7 2.9 3.6 3.3 1.9 4.7 1.6 4.1 2.7 1.6 3.5 4.1 5.9 3.6 2.9 3.9 4.2 4.5 4.2 3.9 3.9 5.8 26.9 25.6 19.2 27.1 29.3 25.5 26.9 13.6 35.9 17.1 29.7 35.2 54.9 15.7 13.6 16.5 43.8 33.9 38.9 23.1 17.6 27.4 2.3 28.9 38.7 23.5 4.2 19.6 22.0 27.2 34.4 33.4 26.5 30.6 17.7 25.2 25.4 16.3 15.6 42.1 35.5 18.3 18.3 15.4 17.5 2.9 26.4 28.2 35.6 13.1 26.7 25.6 27.8 26.7 53.6 38.4 29.9 26.7 28.7 32.8 32.3 17.7 14.7 28.4 32.9 27.6 34.7 25.0 15.6 27.5 31.3 37.4 29.0 10.2 19.5 36.3 MFSD2B ENSG00000205639 "Major facilitator superfamily domain containing 2B" A6NFX1 2 24010081-24063321 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "bone marrow: 11.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 25.1;Erythroid cells: 65.2;Prostatic glandular cells: 41.0;Urothelial cells: 30.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "basophil: 2.9" "Lineage enriched" "Detected in single" 24 "granulocytes: 2.9" "Group enriched" "Detected in some" 14 "HEL: 8.3;K-562: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044145 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA044145: AB_2678833" "unprognostic (5.67e-2)" "unprognostic (1.25e-3)" "unprognostic (1.84e-1)" "unprognostic (5.35e-5)" "unprognostic (2.82e-1)" "unprognostic (1.74e-1)" "unprognostic (4.26e-2)" "unprognostic (7.47e-2)" "unprognostic (2.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.21e-3)" "unprognostic (1.90e-2)" "unprognostic (6.87e-6)" "unprognostic (7.76e-2)" "unprognostic (1.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.72e-1)" 0.0 0.0 0.2 0.0 0.4 11.8 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.4 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 1.3 0.2 0.4 0.5 0.3 0.1 0.3 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.0 1.3 0.3 1.6 10.1 25.1 0.7 0.0 0.9 0.3 0.3 4.6 1.5 0.5 0.0 4.2 6.9 0.2 0.9 3.9 5.0 0.6 0.1 0.3 1.7 1.2 65.2 0.3 1.8 4.4 1.6 0.0 0.3 5.1 0.3 0.4 0.0 3.1 0.0 0.5 2.9 2.0 1.4 5.9 0.8 0.0 4.5 0.0 1.0 0.6 0.1 0.0 0.0 0.3 10.6 2.3 0.0 0.2 41.0 3.1 0.2 0.0 1.5 0.0 1.1 0.7 0.9 2.1 0.0 11.2 7.5 1.1 0.0 5.5 30.3 WDCP "C2orf44, FLJ21945, MMAP" ENSG00000163026 "WD repeat and coiled coil containing" Q9H6R7 2 24029347-24049575 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 9.2;Distal tubular cells: 7.9;Granulosa cells: 4.3;Theca cells: 4.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041054 Approved Approved Nucleoli,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoli Cytosol "HPA041054: AB_10796566" "unprognostic (1.07e-1)" "unprognostic (3.19e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (6.53e-4)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (5.14e-8)" "unprognostic (7.69e-2)" "unprognostic (9.01e-3)" "unprognostic (2.05e-1)" "unprognostic (1.07e-1)" "unprognostic (5.19e-2)" "unprognostic (2.76e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (7.76e-2)" "unprognostic (3.00e-1)" 2.6 3.7 3.9 3.8 4.1 1.4 4.4 4.7 4.0 3.5 4.6 4.2 2.5 4.2 3.7 3.2 3.2 2.7 3.4 3.8 4.0 3.5 4.1 2.6 6.6 3.9 4.1 5.4 2.6 5.0 2.3 4.2 4.0 3.6 2.9 6.3 2.9 4.5 6.1 2.9 3.3 3.5 3.9 4.2 3.0 4.9 4.3 7.7 3.1 8.7 7.0 3.6 2.7 4.6 12.3 18.8 20.1 14.0 13.6 10.7 7.2 14.6 7.8 15.1 14.1 17.2 5.6 32.0 6.2 7.5 12.6 8.8 28.7 10.0 15.6 19.4 16.4 19.7 8.5 17.8 9.3 18.0 13.0 6.5 7.6 15.6 7.7 7.8 14.3 18.4 27.5 8.7 15.9 5.6 23.8 10.8 24.3 12.2 14.3 25.7 33.8 12.9 7.1 6.1 15.4 21.3 7.2 7.0 9.1 14.0 5.4 7.9 13.9 12.0 13.1 7.2 13.6 14.4 19.2 45.2 7.7 19.0 9.5 0.0 1.8 1.1 5.2 2.7 5.3 3.3 3.3 3.8 3.1 2.9 4.6 5.0 0.4 3.9 2.0 1.1 5.4 3.3 3.9 4.1 4.7 4.0 3.8 4.0 3.9 4.1 4.0 3.9 4.3 4.6 3.1 3.2 3.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.7 2.7 0.0 0.0 0.6 9.2 0.0 2.9 1.8 0.0 7.9 2.3 0.0 1.5 3.2 1.6 0.0 0.0 0.0 2.0 2.5 1.4 0.0 1.0 0.0 4.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.1 1.0 4.5 0.0 0.0 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 47.9;NTERA-2: 42.9;SH-SY5Y: 30.7;SuSa: 46.1;TIME: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 5.6 4.4 32.5 2.2 36.1 1.6 5.5 26.5 47.9 6.7 23.0 7.1 19.6 4.8 2.7 8.3 3.9 5.4 5.1 39.2 30.9 8.7 6.6 10.5 1.5 27.7 27.6 5.5 7.5 7.0 6.4 4.0 30.3 7.2 3.3 7.7 6.6 6.3 1.4 6.5 6.8 2.7 25.9 2.8 15.0 1.6 32.7 1.6 6.7 1.2 2.3 5.6 8.1 30.5 0.2 2.0 17.2 0.0 10.9 4.7 6.2 5.8 6.0 2.5 3.6 1.2 2.0 0.0 4.3 10.3 15.4 6.8 25.7 20.2 1.6 3.0 16.1 6.0 0.2 47.9 4.5 0.0 14.1 3.9 4.6 5.9 1.1 14.7 16.5 6.8 1.5 0.1 5.9 0.2 2.0 0.0 42.9 1.7 3.0 3.1 1.5 0.2 2.0 1.3 4.1 30.7 0.3 0.1 5.8 46.1 1.2 2.2 38.0 0.0 5.2 0.2 1.4 1.1 0.5 0.0 6.4 0.0 1.3 0.4 0.4 2.2 0.1 0.4 0.0 0.1 0.2 0.2 1.0 1.2 0.0 0.1 0.0 0.1 0.0 0.2 2.8 0.5 32.5 36.1 26.5 47.9 39.2 30.9 27.7 27.6 30.3 25.9 32.7 30.5 9.3 0.0 6.8 2.9 1.8 9.2 14.0 13.7 11.4 2.1 6.5 13.7 0.9 22.8 4.7 7.3 0.0 4.9 2.7 15.8 13.7 27.6 0.6 3.5 5.0 10.9 9.5 7.0 16.9 38.2 31.9 6.9 16.3 7.1 1.3 3.4 15.7 10.2 7.5 1.7 7.8 8.9 2.0 4.0 17.4 2.9 2.8 9.1 28.4 4.7 13.0 31.4 1.0 2.5 1.3 49.8 25.4 4.1 2.4 15.5 10.6 6.8 2.0 3.6 26.3 2.9 10.6 1.6 5.4 9.1 7.4 5.2 4.9 1.4 4.5 19.3 SF3B6 "CGI-110, Ht006, P14, SAP14a, SF3B14a" ENSG00000115128 "Splicing factor 3b subunit 6" Q9Y3B4 2 24067586-24076373 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034829, HPA034830" Enhanced Supported Nucleoplasm NA NA 11000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA034829: AB_10673104, HPA034830: AB_10669680" "unprognostic (6.37e-2)" "unprognostic (1.38e-1)" "unprognostic (3.59e-1)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (5.35e-3)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.74e-2)" "unprognostic (8.75e-2)" "unprognostic (7.41e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (5.44e-2)" "unprognostic (2.91e-1)" 79.0 86.5 82.4 65.1 84.1 211.2 137.9 86.4 125.3 99.1 82.5 106.2 91.1 84.7 141.9 123.5 89.2 78.2 89.3 82.7 85.7 111.5 132.6 67.3 102.8 85.9 84.2 93.7 63.7 103.0 62.9 88.3 86.3 81.2 108.7 64.4 71.6 84.2 74.7 76.4 84.7 89.0 88.6 65.1 70.4 66.6 82.0 138.6 104.9 106.2 123.3 117.2 85.2 92.4 307.2 152.4 231.6 207.9 182.7 292.8 139.3 233.6 253.8 279.1 284.2 329.9 197.0 236.6 117.3 213.1 265.4 187.7 245.2 293.7 345.5 218.0 263.4 256.6 197.2 299.4 324.4 314.3 151.3 268.5 342.5 281.3 319.3 286.4 288.8 199.4 290.2 181.3 294.2 250.3 234.1 486.1 194.7 362.8 264.0 170.6 327.7 239.1 334.6 189.0 214.4 320.7 123.6 268.3 570.9 195.4 122.7 309.4 173.9 159.6 213.6 157.3 384.4 171.2 239.1 655.3 215.4 515.8 224.5 225.0 118.9 185.7 96.0 133.5 108.1 153.9 122.9 117.8 138.9 114.7 118.0 130.0 173.5 133.7 124.3 129.6 179.6 143.8 82.4 84.1 86.4 125.3 82.7 85.7 85.9 84.2 86.3 88.6 82.0 92.4 207.4 70.5 91.5 11.8 125.1 0.0 280.4 0.0 208.3 50.7 194.3 320.5 120.8 133.0 55.1 138.0 16.7 296.5 149.2 217.1 389.4 206.1 195.9 226.4 208.1 149.0 180.3 164.7 9.2 167.4 413.2 153.0 85.6 210.7 100.1 185.1 142.1 167.1 232.7 18.5 10.2 253.5 0.0 129.3 0.0 49.4 210.3 132.6 0.0 10.3 227.4 175.4 149.3 11.6 19.4 205.4 314.5 180.5 134.0 327.5 381.2 423.1 78.0 68.4 118.3 155.0 158.9 272.4 173.7 257.8 0.0 271.7 126.6 344.4 242.7 438.1 FAM228B ENSG00000219626 "Family with sequence similarity 228 member B" P0C875 2 24076526-24169640 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.9;Late spermatids: 100.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052598, HPA063357" Uncertain Approved "Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Golgi apparatus" "HPA052598: AB_2681880, HPA063357: AB_2684994" "unprognostic (2.48e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (2.66e-1)" "unprognostic (3.81e-1)" "unprognostic (5.05e-2)" "unprognostic (1.85e-2)" "unprognostic (9.14e-2)" "unprognostic (3.32e-1)" "unprognostic (1.32e-1)" "unprognostic (3.39e-5)" "unprognostic (5.62e-2)" "unprognostic (1.02e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (5.15e-1)" "unprognostic (6.93e-2)" 21.8 15.0 44.4 2.9 48.1 7.9 17.1 53.2 63.6 21.1 33.8 20.7 1.7 12.2 19.2 6.8 18.4 9.2 26.0 40.4 47.3 17.0 4.9 11.0 5.5 45.3 43.8 21.4 8.3 14.9 30.6 6.5 45.5 21.6 4.3 8.9 7.5 12.4 13.2 8.2 10.4 7.8 45.6 12.7 11.4 33.4 45.1 6.2 14.0 9.7 5.0 16.9 14.5 54.9 2.6 1.9 3.7 13.9 9.6 12.5 0.4 6.3 5.9 2.3 1.5 0.2 1.6 3.3 3.1 4.8 4.6 0.2 0.9 0.7 2.2 5.0 6.1 4.0 0.6 0.7 18.6 2.0 1.0 11.7 6.5 1.0 9.3 15.5 5.0 3.0 0.4 4.0 3.1 4.1 0.6 9.4 1.2 0.3 5.4 3.2 1.7 1.5 6.8 2.7 1.3 10.0 2.0 0.0 11.3 5.9 3.8 9.3 5.2 4.2 0.4 0.8 2.1 6.7 2.2 3.9 9.2 7.1 2.9 9.4 5.0 10.1 5.2 3.5 2.6 7.4 3.7 4.2 6.0 4.8 5.5 5.7 4.1 4.5 3.3 9.9 3.8 3.1 44.4 48.1 53.2 63.6 40.4 47.3 45.3 43.8 45.5 45.6 45.1 54.9 19.1 51.3 35.3 49.9 10.7 6.4 9.5 8.8 5.2 24.7 11.5 18.7 24.7 10.0 34.9 14.7 8.4 9.7 17.2 1.6 31.3 5.4 116.9 13.2 11.8 17.4 9.6 6.9 52.1 5.5 4.2 20.1 2.6 5.5 25.9 22.3 20.7 3.5 10.4 37.0 52.1 3.2 10.2 12.8 21.7 100.5 42.3 13.2 10.6 39.4 14.7 39.0 21.6 41.7 78.3 3.8 1.1 38.4 4.6 4.3 2.4 12.3 41.9 27.7 52.6 24.3 21.6 39.4 11.4 2.6 7.4 3.3 13.2 17.4 3.1 5.4 TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.8;Late spermatids: 213.9;Proximal enterocytes: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "T-47d: 599.7" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" 20.2 24.6 8.6 16.1 9.8 20.0 17.2 8.4 9.6 29.6 11.2 54.4 51.5 17.3 4.5 119.2 16.5 26.3 15.4 7.5 9.0 46.8 15.2 29.9 7.2 9.4 11.1 8.2 40.1 7.0 11.7 10.6 8.5 15.0 40.8 2.0 25.3 11.2 6.2 8.0 69.1 16.9 7.7 11.9 25.3 38.4 13.0 14.2 23.6 5.9 10.1 22.3 63.8 9.7 27.5 86.8 50.6 21.1 38.8 85.3 37.2 27.3 32.3 22.6 31.1 22.1 48.4 3.5 15.0 44.0 6.1 8.0 13.1 46.5 13.8 21.6 2.0 8.7 33.3 57.5 25.2 4.1 15.3 92.3 72.3 60.2 14.7 46.1 102.0 16.3 7.3 23.4 95.5 18.1 5.0 0.6 39.2 30.8 36.0 10.1 45.7 0.9 38.1 41.4 7.2 32.9 35.1 7.8 6.1 40.5 599.7 5.6 80.6 26.9 63.8 18.5 13.7 10.6 7.4 3.0 8.9 0.4 7.0 11.8 19.1 16.9 0.2 12.6 0.2 4.9 0.2 0.6 16.0 5.5 0.1 0.4 4.1 0.3 5.6 7.1 0.5 6.1 8.6 9.8 8.4 9.6 7.5 9.0 9.4 11.1 8.5 7.7 13.0 9.7 19.2 28.9 38.4 3.9 6.8 4.7 24.7 69.7 6.8 0.8 25.8 33.0 9.0 50.1 51.9 42.3 0.0 41.9 1.1 175.8 109.5 93.5 127.8 50.4 47.4 20.3 79.4 7.2 0.4 134.7 31.9 30.6 83.6 68.2 12.7 85.8 23.9 12.9 45.0 0.0 0.4 63.9 57.0 22.9 11.1 213.9 7.8 20.9 14.2 4.7 23.9 9.5 0.0 5.0 0.3 91.1 138.5 9.1 8.0 11.4 200.9 104.7 19.2 1.9 19.7 14.1 36.8 56.6 14.3 38.8 7.0 28.9 3.4 16.2 75.2 49.9 PFN4 ENSG00000176732 "Profilin family member 4" Q8NHR9 2 24114809-24123464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 27 "testis: 81.1" "Group enriched" "Detected in some" 6 "Early spermatids: 491.1;Spermatocytes: 319.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.20e-3)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "unprognostic (1.24e-1)" "unprognostic (3.52e-2)" "unprognostic (1.37e-1)" "unprognostic (4.56e-4)" "unprognostic (1.25e-1)" "unprognostic (3.82e-2)" "unprognostic (2.21e-2)" "unprognostic (2.74e-2)" "unprognostic (8.97e-3)" "unprognostic (1.77e-5)" "unprognostic (2.55e-2)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (9.10e-2)" 0.8 0.6 1.6 0.2 1.2 0.2 1.3 1.4 1.7 0.7 1.2 0.4 0.2 0.9 2.0 0.8 1.7 0.6 1.2 1.0 1.1 1.2 0.3 0.8 0.5 1.0 1.2 1.8 0.4 1.0 1.2 0.5 1.1 0.8 0.6 3.0 0.7 0.7 1.0 0.6 0.4 0.4 0.7 0.7 0.3 81.1 1.1 0.4 1.9 0.5 0.7 0.4 0.6 1.3 2.0 1.0 0.4 1.8 1.9 1.9 0.7 0.6 0.3 0.6 0.4 0.4 2.1 1.2 0.3 0.0 2.3 0.2 0.0 0.2 0.2 1.5 0.0 0.1 0.5 0.0 1.1 0.3 0.1 2.4 1.2 0.5 1.2 0.4 0.3 1.3 0.4 1.1 1.0 1.4 0.3 0.6 0.4 0.0 1.3 0.4 1.0 0.0 1.0 0.2 1.1 1.6 0.7 0.2 0.6 0.7 2.1 0.4 0.9 0.9 0.7 0.1 0.7 1.7 1.7 1.1 1.6 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.2 1.4 1.7 1.0 1.1 1.0 1.2 1.1 0.7 1.1 1.3 0.3 0.0 1.1 0.7 0.2 0.3 0.6 0.4 0.0 0.8 0.9 0.6 2.4 0.0 0.3 0.0 0.0 0.4 0.2 0.1 3.9 0.5 491.1 4.6 0.9 1.1 0.0 0.0 1.3 1.4 0.7 0.7 0.0 0.7 0.0 1.7 0.4 0.8 1.0 1.7 1.7 0.2 0.0 0.0 0.0 66.9 6.5 0.7 0.0 0.0 0.0 1.1 0.0 0.5 1.4 0.8 0.0 1.9 0.1 0.3 0.1 2.0 4.3 1.0 0.0 0.5 0.5 319.1 3.6 0.0 0.6 0.3 0.1 0.8 0.2 0.4 FAM228A "C2orf84, FLJ30851" ENSG00000186453 "Family with sequence similarity 228 member A" Q86W67 2 24175053-24200849 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 35.1" "Group enriched" "Detected in some" 5 "Early spermatids: 119.7;Spermatocytes: 176.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.5;hTERT-RPE1: 1.1;TIME: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075817 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA075817: " "unprognostic (2.57e-1)" "unprognostic (7.14e-2)" "unprognostic (2.92e-2)" "unprognostic (1.98e-3)" "unprognostic (7.13e-4)" "unprognostic (2.19e-3)" "unprognostic (1.55e-1)" "unprognostic (3.05e-1)" "unprognostic (9.57e-2)" "unprognostic (2.14e-1)" "unprognostic (4.44e-5)" "unprognostic (1.73e-2)" "unprognostic (1.04e-4)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.33e-2)" 2.0 0.9 1.9 0.6 1.7 0.0 1.6 1.4 2.8 0.9 0.0 0.9 0.3 0.7 0.9 0.9 0.6 1.1 1.7 1.3 1.0 0.8 0.3 0.8 0.6 0.8 0.7 0.7 0.3 0.1 0.4 1.0 0.8 0.8 0.3 0.9 0.2 0.9 0.4 0.4 0.4 0.5 0.2 0.4 0.7 35.1 0.7 0.3 0.6 0.4 0.2 0.9 0.5 1.9 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.5 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.2 0.2 0.0 0.1 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.1 1.9 1.7 1.4 2.8 1.3 1.0 0.8 0.7 0.8 0.2 0.7 1.9 0.4 3.2 0.5 3.3 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.7 119.7 0.0 0.4 0.5 0.0 0.0 5.5 0.5 0.2 1.6 0.0 0.0 0.0 0.6 1.1 0.1 0.5 1.7 5.8 0.0 0.0 0.8 0.4 24.8 2.8 0.3 0.0 2.8 0.1 0.3 1.0 3.0 3.1 0.7 0.0 4.5 0.0 0.1 0.0 0.0 0.1 0.2 6.6 1.0 0.8 176.0 10.4 0.0 0.1 0.1 0.1 0.5 0.0 0.2 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 PTRHD1 "C2orf79, LOC391356" ENSG00000184924 "Peptidyl-tRNA hydrolase domain containing 1" Q6GMV3 2 24789728-24793391 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019951 Approved Approved Nucleoplasm NA NA 100000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA019951: AB_1853109" "unprognostic (1.28e-2)" "unprognostic (5.79e-2)" "unprognostic (6.34e-2)" "unprognostic (1.34e-2)" "unprognostic (2.61e-2)" "unprognostic (3.99e-1)" "unprognostic (8.84e-3)" "unprognostic (1.26e-1)" "unprognostic (3.69e-1)" "unprognostic (8.31e-3)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.51e-1)" "unprognostic (5.76e-2)" 10.6 26.0 11.7 4.3 11.8 16.1 11.0 12.2 17.5 8.7 13.7 12.8 10.6 7.2 3.5 17.6 6.4 4.2 16.4 12.5 12.6 14.9 14.9 10.2 8.4 12.4 11.9 10.2 13.7 3.6 10.8 6.4 12.6 10.6 5.8 3.0 15.1 4.0 23.9 14.8 11.9 3.3 12.5 11.2 12.3 9.1 12.8 7.1 14.5 8.5 6.2 9.4 10.3 13.0 18.2 40.2 12.7 5.5 6.9 15.2 22.1 12.2 11.3 15.4 9.9 39.7 15.9 14.2 5.2 12.7 10.3 11.7 10.4 11.1 5.1 20.1 70.0 25.7 18.2 43.2 14.2 21.8 23.5 14.6 8.9 7.1 7.9 12.3 14.4 12.8 26.4 11.2 11.4 36.6 17.7 39.0 26.8 10.6 23.7 14.9 38.9 23.9 18.1 31.2 19.9 30.9 13.6 18.1 16.4 5.9 17.7 15.9 24.2 13.6 21.4 6.7 11.2 8.7 28.1 15.4 12.4 13.3 9.3 34.8 90.6 20.7 52.6 66.9 26.8 96.4 51.4 46.2 144.5 81.2 46.6 54.8 10.4 52.8 50.1 149.0 84.4 97.0 11.7 11.8 12.2 17.5 12.5 12.6 12.4 11.9 12.6 12.5 12.8 13.0 27.8 51.3 61.5 1.0 65.0 119.8 79.4 123.3 72.3 10.5 171.4 239.4 81.0 60.1 83.8 66.2 6.2 200.0 87.9 127.0 115.4 91.0 130.9 53.5 37.5 46.9 88.1 68.1 1.9 142.0 153.7 57.4 50.4 48.8 41.2 121.1 62.4 101.5 134.5 1.7 2.2 158.2 79.3 112.5 154.3 157.1 47.2 79.9 67.6 3.7 154.6 78.7 65.9 1.0 2.3 124.2 128.8 39.9 46.6 74.3 120.9 199.2 107.1 12.2 72.3 34.5 56.0 135.6 78.6 133.6 141.8 167.7 52.5 110.4 162.2 125.3 CENPO "CENP-O, MGC11266" ENSG00000138092 "Centromere protein O" Q9BU64 2 24793136-24822376 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 11.2;Extravillous trophoblasts: 11.5;Spermatocytes: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046189 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA046189: AB_2679579" "unprognostic (1.67e-2)" "unprognostic (2.42e-1)" "unprognostic (1.98e-2)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.79e-1)" "unprognostic (7.48e-3)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.56e-2)" "unprognostic (4.02e-1)" "unprognostic (4.81e-2)" "unprognostic (5.93e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (5.71e-13)" "unprognostic (4.23e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "unprognostic (1.96e-1)" 5.2 4.0 3.5 3.5 3.3 9.2 4.6 2.9 4.1 4.0 2.3 3.3 3.2 3.1 0.8 4.5 3.0 1.5 2.8 3.7 3.5 2.9 2.6 3.6 4.9 3.7 3.4 4.5 1.9 1.6 3.6 3.2 3.5 3.1 3.7 1.4 2.5 1.1 3.0 3.8 3.9 2.2 3.2 4.3 2.7 8.3 3.8 11.4 3.4 2.0 5.8 2.5 3.7 3.1 31.1 36.4 40.7 21.7 4.8 7.3 22.7 36.8 21.7 51.0 38.7 46.2 15.5 21.4 4.2 22.8 29.8 16.3 40.6 14.0 34.1 28.1 21.1 34.3 23.9 31.0 2.4 28.7 24.4 3.6 2.5 51.5 11.4 9.3 24.0 25.4 40.3 23.8 31.8 21.8 39.2 20.6 29.3 21.0 22.8 31.0 53.4 11.5 12.9 18.6 27.0 29.3 22.1 16.9 7.9 18.5 16.3 11.8 15.4 46.9 42.8 15.9 41.6 14.5 20.1 42.8 14.5 27.5 36.4 0.0 0.3 0.0 1.0 0.2 0.4 0.4 0.4 0.5 0.4 0.3 0.3 0.7 0.1 0.7 0.3 1.1 0.7 0.3 3.5 3.3 2.9 4.1 3.7 3.5 3.7 3.4 3.5 3.2 3.8 3.1 0.7 3.2 2.2 4.2 1.5 1.1 0.7 1.3 2.2 0.9 1.9 1.4 6.5 0.0 1.2 3.7 0.0 3.9 1.9 3.0 1.9 1.5 3.9 1.5 2.2 2.0 0.0 11.2 5.3 1.3 11.5 2.4 6.6 1.5 1.3 6.5 1.8 0.9 4.9 1.7 4.9 1.6 0.0 1.6 1.1 9.6 0.3 1.1 1.8 3.7 1.2 1.6 1.0 2.0 2.5 1.1 0.5 1.2 8.6 0.5 1.8 1.7 0.7 0.7 0.0 1.1 3.3 11.7 9.5 3.3 1.4 2.9 1.4 2.8 2.7 0.9 ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 58.4;Sertoli cells: 111.7;Smooth muscle cells: 62.8;Theca cells: 92.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010223 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB010223: AB_630839" "unprognostic (3.05e-1)" "unprognostic (1.10e-1)" "unprognostic (4.91e-2)" "unprognostic (1.39e-3)" "unprognostic (5.01e-2)" "unprognostic (7.66e-2)" "unprognostic (1.28e-1)" "unprognostic (6.06e-2)" "unprognostic (8.43e-2)" "unprognostic (6.89e-2)" "unprognostic (8.22e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (1.32e-9)" "unprognostic (3.74e-2)" "unprognostic (5.56e-2)" "unprognostic (1.11e-1)" "unprognostic (8.55e-3)" 94.4 17.3 43.5 17.3 55.1 17.7 74.6 36.7 50.1 66.7 28.4 27.5 10.9 56.4 20.5 30.4 62.1 23.0 36.6 43.3 43.4 25.9 6.6 42.5 18.9 41.6 43.8 71.9 15.7 17.0 41.7 83.6 41.1 40.6 15.8 4.2 21.6 33.0 15.2 38.4 34.4 35.3 36.9 30.4 25.0 9.8 50.6 11.4 36.8 20.4 18.1 36.4 48.9 44.9 76.5 40.4 17.2 28.3 84.5 75.4 29.6 32.3 65.9 37.1 37.8 38.6 25.1 26.0 6.2 53.2 51.0 54.5 43.1 54.5 24.0 58.4 55.8 43.0 40.0 1.7 64.0 24.0 24.6 55.7 47.5 36.6 50.8 23.6 33.8 27.9 15.5 49.2 19.3 43.6 17.9 2.1 14.9 39.9 24.4 38.8 75.3 59.5 15.5 38.7 31.6 19.1 45.8 54.2 30.2 13.0 13.5 22.5 33.5 59.7 34.2 39.1 54.1 42.4 101.6 113.6 18.7 39.2 31.4 2.6 1.5 0.0 0.4 1.6 0.3 5.5 0.9 0.5 9.5 6.0 0.7 0.5 0.0 1.2 0.4 9.0 3.4 1.0 43.5 55.1 36.7 50.1 43.3 43.4 41.6 43.8 41.1 36.9 50.6 44.9 14.6 0.0 1.8 17.0 8.2 11.0 4.2 4.1 5.2 3.0 18.6 8.0 2.8 0.0 1.3 1.8 0.0 1.0 5.2 5.0 0.0 0.9 0.3 1.9 42.2 10.6 1.2 5.2 40.1 0.0 2.1 25.5 2.0 2.2 18.4 3.7 5.0 0.3 12.6 0.0 36.8 6.0 2.0 5.4 6.9 3.9 58.4 10.1 7.2 21.5 4.0 1.6 0.0 15.1 33.2 1.0 5.8 29.3 4.9 11.2 8.3 0.2 1.1 2.2 111.7 6.5 62.8 0.4 2.4 4.4 11.8 1.2 7.2 92.9 12.1 3.9 DNAJC27 "RabJS, RBJ" ENSG00000115137 "DnaJ heat shock protein family (Hsp40) member C27" Q9NZQ0 2 24943636-24972094 "Predicted intracellular proteins" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 59.8;Spermatocytes: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036815, HPA036816" Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 29: U-266 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA036815: , HPA036816: AB_10673506" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (1.63e-1)" "unprognostic (4.53e-2)" "unprognostic (3.09e-1)" "unprognostic (5.17e-3)" "unprognostic (5.41e-2)" "unprognostic (5.58e-3)" "unprognostic (2.13e-1)" "unprognostic (4.60e-2)" "unprognostic (7.44e-4)" "unprognostic (8.84e-2)" "prognostic favorable (8.48e-5)" "unprognostic (3.35e-1)" "unprognostic (3.66e-1)" "unprognostic (3.05e-2)" "unprognostic (1.78e-3)" 5.6 3.4 4.3 2.1 5.6 3.8 3.7 7.1 7.0 3.7 4.1 3.7 1.9 4.2 5.0 2.2 4.6 3.0 4.9 4.6 8.7 3.8 2.0 2.7 2.7 7.5 6.5 7.0 2.7 5.1 6.1 2.9 8.2 3.3 2.7 13.3 2.2 3.1 4.6 2.9 2.7 3.0 5.7 2.9 2.9 22.2 6.0 3.5 3.3 7.0 2.4 3.1 2.9 6.5 2.8 1.2 2.6 2.6 3.6 3.0 2.0 2.1 3.2 2.2 1.9 1.3 1.3 2.6 0.5 1.5 1.8 2.2 1.9 1.3 2.3 1.1 1.6 1.6 1.6 1.2 2.3 1.5 2.2 2.3 2.2 1.7 3.5 2.5 0.9 3.1 1.1 2.4 2.4 1.0 2.7 2.6 1.7 1.0 1.1 1.6 5.1 1.4 2.1 1.5 0.9 3.2 2.0 1.5 3.0 2.7 1.3 1.1 0.8 2.9 2.0 1.5 2.0 6.1 2.3 3.1 1.5 2.4 1.3 0.0 0.2 0.9 0.2 0.1 0.5 0.4 0.3 0.2 0.2 0.3 0.4 0.5 0.0 1.3 0.3 0.1 0.3 0.2 4.3 5.6 7.1 7.0 4.6 8.7 7.5 6.5 8.2 5.7 6.0 6.5 7.8 9.6 10.0 19.2 11.2 2.0 5.6 3.6 8.0 24.1 9.8 8.5 25.4 4.3 3.0 7.3 37.5 3.6 10.8 4.5 3.9 2.6 59.8 12.5 9.7 7.7 15.5 11.8 18.2 2.5 2.0 8.8 8.2 5.2 10.8 9.5 6.1 3.4 3.3 37.0 22.1 5.9 6.1 3.2 4.6 32.5 8.7 5.9 1.8 7.5 4.3 12.2 4.1 12.1 24.1 1.7 0.9 6.4 8.8 4.6 4.3 3.1 17.3 25.1 0.0 12.8 23.9 70.7 17.0 8.3 3.3 4.2 11.3 23.2 5.4 3.8 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 POMC "ACTH, CLIP, LPH, MSH, NPP, POC" ENSG00000115138 Proopiomelanocortin P01189 2 25160853-25168903 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Endorphin, Hormone" "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 903 "pituitary gland: 34360.0" "Cell type enhanced" "Detected in many" "Early spermatids: 119.8;Late spermatids: 352.6;Spermatocytes: 83.0" "Cancer enriched" "Detected in many" 6 "testis cancer: 18.5" "Group enriched" "Detected in all" 6 "hypothalamus: 38.0;thalamus: 13.1" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;THP-1: 2.1" "Region enriched" "Detected in all" 7 "hypothalamus: 44.0" "Region enriched" "Detected in all" 5 "hypothalamus: 88.1" "CAB002762, HPA046135, HPA063644, CAB079881" Enhanced "Secreted to blood" NA NA 380000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "CAB002762: , CAB079881: , HPA046135: AB_2679552, HPA063644: AB_2685071" "unprognostic (8.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.78e-2)" "unprognostic (1.96e-3)" "unprognostic (3.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (4.30e-2)" "unprognostic (8.74e-3)" "unprognostic (1.38e-1)" "prognostic favorable (5.70e-4)" "unprognostic (8.02e-2)" "unprognostic (4.29e-2)" "unprognostic (2.94e-3)" "unprognostic (1.42e-1)" "unprognostic (1.37e-3)" "unprognostic (3.84e-2)" 6.1 19.1 2.7 1.2 2.8 1.1 3.5 3.2 4.4 3.0 2.2 6.9 0.4 3.1 0.3 13.7 2.2 0.2 12.1 2.3 38.0 4.9 12.9 3.5 1.1 4.5 3.3 5.0 22.6 0.1 34360.0 1.2 3.7 5.0 0.0 0.2 5.8 0.3 5.7 35.7 4.8 0.1 4.0 11.1 15.5 25.7 13.1 1.2 8.4 5.2 0.4 2.5 3.7 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 12.6 8.6 11.5 13.2 9.1 16.8 8.8 11.3 15.9 17.4 11.6 12.6 3.8 18.2 8.0 27.9 10.5 9.7 2.7 2.8 3.2 4.4 2.3 38.0 4.5 3.3 3.7 4.0 13.1 3.5 22.3 0.0 2.2 1.0 16.1 4.5 2.2 6.9 2.2 2.6 6.1 6.7 2.5 2.8 2.5 0.0 0.0 0.5 24.4 0.2 15.6 7.8 119.8 0.6 4.9 11.6 0.0 28.8 0.3 17.3 6.0 5.2 4.6 0.6 7.0 9.7 15.4 2.0 34.5 6.7 0.6 0.0 6.1 10.9 7.9 352.6 4.7 17.2 17.8 1.9 8.5 11.5 15.5 0.0 0.3 10.1 1.1 13.2 17.8 4.1 0.1 3.9 0.7 7.5 13.1 4.6 3.8 83.0 27.3 1.6 5.5 0.4 14.9 12.9 0.6 3.8 DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 127.2;Horizontal cells: 95.9;Rod photoreceptor cells: 143.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 59.6;REH: 59.5;SH-SY5Y: 71.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009469, HPA026588" Approved Supported Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB009469: AB_2093990, HPA026588: AB_1847812" "unprognostic (2.38e-1)" "unprognostic (2.94e-1)" "unprognostic (5.65e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (8.38e-2)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (2.24e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.18e-4)" "unprognostic (2.35e-2)" "prognostic unfavorable (2.49e-4)" "unprognostic (1.43e-1)" "unprognostic (1.87e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-2)" 5.6 9.0 8.9 9.8 12.6 8.7 6.2 9.3 10.7 9.1 2.4 11.3 6.7 9.3 8.7 6.0 7.5 6.3 5.9 8.8 7.9 11.3 5.3 7.3 11.1 9.0 7.6 13.0 8.3 4.2 11.5 15.7 8.6 7.2 6.6 15.4 6.2 5.9 21.0 4.9 8.9 7.1 5.2 13.4 8.5 5.2 9.4 20.6 6.9 10.2 9.0 7.3 6.2 11.3 1.6 8.1 34.6 8.3 3.8 2.7 45.2 1.9 2.2 4.7 3.8 21.1 13.2 0.0 4.7 4.7 3.5 2.2 3.8 5.2 2.8 5.7 4.3 14.7 12.8 25.4 8.8 2.9 7.6 8.2 2.6 6.0 2.2 9.1 19.5 34.0 18.0 2.9 3.5 20.6 33.7 36.5 59.6 14.3 4.2 59.5 32.5 3.8 2.9 3.4 18.6 71.5 2.7 19.6 6.2 29.5 2.1 16.2 6.8 5.4 4.7 1.0 2.5 5.6 5.1 19.6 2.2 8.4 5.5 2.8 1.0 2.1 2.7 1.7 4.0 1.3 1.7 2.4 1.3 1.6 4.6 3.9 2.5 5.5 2.7 2.3 1.9 1.2 8.9 12.6 9.3 10.7 8.8 7.9 9.0 7.6 8.6 5.2 9.4 11.3 18.5 6.4 13.1 28.1 11.0 5.2 10.2 6.6 5.7 73.3 12.1 9.8 15.8 5.7 9.9 20.2 127.2 40.6 15.3 6.3 5.9 16.9 1.6 13.3 19.1 20.5 13.1 15.8 49.4 9.8 10.7 16.4 9.7 10.7 37.4 37.3 11.0 6.4 23.2 95.9 43.2 11.4 2.0 14.2 3.9 1.9 19.3 13.7 7.2 38.4 7.4 20.6 13.4 36.7 63.4 9.3 9.4 15.4 9.8 12.4 6.2 6.6 7.3 143.5 19.7 15.1 14.3 2.8 14.6 8.1 2.6 32.2 19.6 26.1 12.1 10.2 DTNB ENSG00000138101 "Dystrobrevin beta" O60941 2 25377198-25673647 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 36.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.8;Inhibitory neurons: 214.1;Oligodendrocyte precursor cells: 137.7;Oligodendrocytes: 343.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA061357 Uncertain Approved Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria "HPA061357: AB_2684489" "unprognostic (1.14e-1)" "unprognostic (1.39e-2)" "unprognostic (3.17e-2)" "unprognostic (7.40e-2)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (1.78e-2)" "unprognostic (3.67e-3)" "unprognostic (3.98e-2)" "unprognostic (9.45e-2)" "unprognostic (4.67e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (6.49e-2)" 2.1 2.1 7.8 1.6 6.7 2.9 9.7 3.4 12.1 4.2 0.0 1.7 1.2 2.8 10.1 4.5 4.6 3.3 2.0 12.4 3.6 4.2 3.4 4.3 2.5 4.9 1.7 4.4 7.7 9.9 5.8 1.9 4.5 8.4 1.0 5.0 36.0 5.1 2.7 4.5 1.6 1.2 0.1 2.7 5.6 6.7 2.9 4.0 11.1 1.5 1.9 3.5 4.0 5.6 10.7 9.1 6.6 7.5 4.0 5.2 0.2 3.2 4.2 4.0 5.3 3.5 2.6 5.5 1.3 2.5 5.0 3.7 4.6 13.1 2.2 8.2 11.1 4.5 2.9 10.0 2.9 5.4 4.1 3.6 10.9 4.2 7.2 4.9 5.5 10.5 0.4 8.0 3.0 10.9 8.5 4.6 7.3 2.9 5.4 7.0 11.5 9.7 4.9 9.7 8.9 13.7 10.3 16.2 12.9 3.6 8.7 3.3 2.3 1.6 7.3 2.4 5.7 14.6 6.8 10.0 4.6 9.5 5.7 0.4 1.6 5.7 4.1 0.9 4.4 4.4 5.0 3.7 0.5 5.8 5.0 3.3 3.2 4.1 0.4 0.9 5.2 2.0 7.8 6.7 3.4 12.1 12.4 3.6 4.9 1.7 4.5 0.1 2.9 5.6 3.9 9.6 12.8 53.2 12.6 8.0 26.6 16.4 44.3 9.4 20.3 18.9 2.3 7.2 9.3 14.7 6.2 3.7 4.2 0.9 11.7 4.0 3.1 7.2 4.2 4.7 3.0 4.4 176.8 11.6 1.5 3.2 15.8 12.1 1.3 4.6 5.0 5.6 33.6 21.9 214.1 2.8 14.2 7.8 1.7 6.9 1.5 4.9 12.4 83.4 3.2 18.5 7.2 137.7 343.3 9.5 1.4 2.6 8.7 17.9 0.3 9.3 2.2 9.9 6.6 1.9 3.2 12.6 27.9 15.7 2.0 2.1 10.8 2.3 1.3 17.7 ASXL2 "ASXH2, FLJ10898, KIAA1685" ENSG00000143970 "ASXL transcriptional regulator 2" Q76L83 2 25733753-25878487 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034646, HPA058040" Enhanced Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA034646: AB_2674261, HPA058040: AB_2683586" "unprognostic (4.78e-2)" "unprognostic (3.41e-2)" "unprognostic (2.23e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.88e-2)" "unprognostic (2.98e-2)" "unprognostic (2.80e-1)" "unprognostic (2.68e-3)" "unprognostic (3.17e-2)" "unprognostic (1.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-3)" "unprognostic (1.82e-1)" "unprognostic (1.58e-1)" "unprognostic (2.31e-1)" "unprognostic (3.75e-2)" 6.8 6.2 3.8 9.5 5.1 8.3 7.2 4.8 3.9 8.2 4.5 9.1 6.4 7.1 5.0 7.7 7.2 6.8 7.1 3.5 7.7 8.7 6.1 6.9 11.1 7.5 5.0 6.6 7.7 14.1 3.5 7.1 7.5 6.3 8.9 8.8 6.6 6.3 8.0 7.6 7.1 8.2 3.6 9.9 7.8 17.7 6.3 13.9 10.5 7.3 10.5 7.5 4.2 6.4 25.1 23.1 11.0 7.8 9.8 13.7 12.9 16.0 19.0 12.4 10.5 19.4 12.6 14.8 9.7 13.9 13.8 14.1 21.1 14.9 16.9 22.5 10.2 32.9 20.1 16.6 8.3 42.2 25.1 6.8 15.2 17.9 15.3 10.4 15.2 8.8 29.0 12.2 12.5 9.2 15.5 9.2 14.4 13.2 9.4 15.4 48.2 11.4 10.7 30.1 11.3 12.5 22.2 13.9 13.5 10.4 8.9 12.3 31.4 16.6 22.0 15.9 22.4 26.8 39.8 41.0 15.5 27.4 13.2 1.7 2.7 4.2 2.7 1.4 2.3 2.2 1.9 1.9 1.5 2.0 2.2 2.5 6.0 1.2 3.3 2.3 2.2 0.8 3.8 5.1 4.8 3.9 3.5 7.7 7.5 5.0 7.5 3.6 6.3 6.4 16.1 25.6 24.1 54.2 25.9 32.4 8.9 15.9 29.0 22.3 19.1 10.8 27.0 14.3 19.1 9.2 25.0 10.2 22.5 20.1 15.6 15.7 48.9 25.8 20.4 22.0 10.3 33.6 62.5 14.4 9.4 17.3 24.5 19.8 23.5 12.6 28.5 12.6 18.2 25.2 47.6 16.8 18.3 25.7 23.6 26.9 19.6 25.2 23.2 68.4 34.4 12.4 12.3 46.3 72.8 18.4 14.2 13.2 29.8 13.4 12.4 14.3 41.3 24.9 39.5 20.6 16.8 34.4 26.6 29.7 41.1 14.6 45.0 17.2 19.7 19.3 KIF3C ENSG00000084731 "Kinesin family member 3C" O14782 2 25926598-25982749 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 75.5;retina: 19.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.5;Horizontal cells: 42.1;Inhibitory neurons: 45.9;Oligodendrocyte precursor cells: 27.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 54.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035755 Approved "Nuclear membrane,Nuclear bodies,Intermediate filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nuclear bodies, Intermediate filaments" "Nuclear membrane" "HPA035755: AB_10602242" "unprognostic (3.95e-1)" "unprognostic (1.40e-2)" "unprognostic (7.85e-2)" "prognostic unfavorable (1.32e-5)" "unprognostic (2.75e-1)" "unprognostic (4.69e-2)" "unprognostic (3.96e-4)" "unprognostic (1.53e-2)" "prognostic favorable (1.22e-4)" "unprognostic (2.03e-1)" "unprognostic (2.20e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (7.57e-4)" "unprognostic (3.90e-2)" "unprognostic (3.54e-1)" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" 3.1 6.8 28.4 2.3 40.2 1.5 2.9 6.9 75.5 4.0 0.0 5.4 1.3 3.6 1.7 2.2 2.7 3.6 2.9 46.1 18.6 1.6 0.7 2.0 1.2 37.5 10.9 6.8 1.4 3.7 11.7 2.1 32.7 2.9 1.7 19.6 2.2 3.8 1.8 2.5 2.5 4.2 0.0 1.6 2.3 2.3 13.8 2.6 3.0 2.5 1.1 2.7 3.7 37.8 25.7 38.1 19.9 15.4 11.4 13.1 15.9 13.1 6.4 7.7 8.7 6.8 3.8 0.0 10.6 11.9 24.1 2.7 15.2 7.8 5.2 4.5 7.3 9.3 2.6 14.0 6.7 2.3 7.7 9.6 2.3 24.2 4.8 29.6 25.8 7.3 3.3 3.2 8.3 1.8 6.7 3.2 20.5 0.7 11.1 10.4 9.9 1.7 17.7 6.2 24.2 54.4 5.2 2.2 27.3 16.4 0.8 3.1 20.6 13.4 13.7 6.1 12.9 0.8 4.6 3.1 30.4 12.5 11.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.1 0.1 0.5 0.2 0.0 0.0 0.4 0.3 28.4 40.2 6.9 75.5 46.1 18.6 37.5 10.9 32.7 0.0 13.8 37.8 1.9 0.0 0.0 9.4 0.2 0.5 1.6 1.5 1.2 16.7 2.0 2.4 3.5 2.8 1.1 0.0 6.2 0.6 2.1 0.1 0.0 8.4 3.4 1.0 2.1 5.6 3.0 0.0 53.5 1.4 4.2 2.6 0.5 1.4 7.0 8.8 7.9 0.1 3.5 42.1 45.9 0.3 2.0 4.6 1.1 4.8 1.8 2.6 3.6 12.2 2.0 7.0 0.0 27.6 13.7 10.1 0.0 4.5 1.5 1.0 0.0 1.2 1.3 9.6 6.6 2.8 3.1 0.3 1.6 1.0 0.3 1.2 1.7 5.1 0.2 1.0 RAB10 ENSG00000084733 "RAB10, member RAS oncogene family" P61026 2 26034084-26137454 "Enzymes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Suprabasal keratinocytes: 488.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045611 Approved NA Yes 4300000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 10: Non-specific - Unknown function" "HPA045611: AB_10961124" "unprognostic (7.73e-3)" "unprognostic (2.45e-2)" "unprognostic (8.21e-3)" "prognostic unfavorable (7.40e-4)" "unprognostic (8.22e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.99e-5)" "unprognostic (9.22e-3)" "unprognostic (6.14e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (7.37e-5)" "unprognostic (1.06e-2)" "unprognostic (8.69e-3)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.99e-2)" 47.4 51.5 42.8 44.2 49.0 17.7 45.1 48.7 56.7 55.6 29.7 58.8 41.3 38.9 40.3 172.9 39.6 41.9 49.8 41.2 47.3 56.8 48.5 39.9 42.8 52.9 46.9 37.1 37.7 66.3 21.5 40.9 54.4 42.6 57.9 29.0 51.7 41.6 213.9 71.0 46.3 48.1 51.5 44.4 58.8 24.0 46.4 43.8 54.2 114.0 64.5 78.5 78.1 62.8 117.1 139.7 63.8 53.1 131.2 108.2 61.9 90.3 76.8 69.7 61.6 83.2 83.8 77.9 83.4 96.7 79.5 62.0 77.3 84.4 73.9 82.3 56.0 135.1 54.4 134.8 122.6 112.2 73.5 89.0 135.9 85.9 100.3 109.6 89.0 48.9 114.1 76.7 95.1 52.0 69.1 87.1 65.2 139.5 81.7 65.2 133.4 132.8 141.6 111.8 90.1 83.7 75.2 135.1 94.9 70.5 59.5 80.1 110.2 107.1 56.2 75.7 97.2 50.5 84.2 124.4 107.9 132.6 83.5 58.0 75.5 35.5 31.5 135.2 38.6 33.4 36.9 34.1 69.9 32.0 31.1 35.2 54.6 50.6 152.6 24.3 44.6 81.0 42.8 49.0 48.7 56.7 41.2 47.3 52.9 46.9 54.4 51.5 46.4 62.8 70.8 80.1 49.7 37.9 56.2 341.8 195.5 156.4 122.3 23.8 85.2 64.6 76.4 85.8 134.7 92.0 8.4 121.0 48.7 168.8 115.4 188.3 35.5 67.8 76.7 78.4 65.2 101.0 43.6 96.0 204.4 80.7 97.3 98.3 50.7 44.0 53.2 66.8 159.7 26.9 36.0 94.1 107.8 157.2 285.1 29.6 62.7 151.6 88.9 36.5 246.8 104.9 38.1 47.7 78.1 136.8 123.8 70.0 63.6 199.7 85.9 135.2 107.4 32.7 85.5 94.1 159.5 85.3 73.4 255.9 488.0 128.3 59.3 65.6 117.7 334.3 GAREM2 "FAM59B, FLJ00375, GAREML, KIAA2038" ENSG00000157833 "GRB2 associated regulator of MAPK1 subtype 2" Q75VX8 2 26173088-26189663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 37.2;choroid plexus: 10.4;parathyroid gland: 22.9" "Group enriched" "Detected in many" 4 "Distal tubular cells: 46.9;Muller glia cells: 19.5;Proximal tubular cells: 42.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 16.8;SH-SY5Y: 10.2;U-2 OS: 13.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071575 Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA071575: AB_2686420" "unprognostic (1.70e-2)" "unprognostic (5.62e-2)" "unprognostic (7.61e-4)" "unprognostic (1.56e-2)" "unprognostic (8.27e-2)" "unprognostic (2.19e-1)" "unprognostic (2.90e-2)" "unprognostic (1.99e-1)" "unprognostic (2.12e-2)" "unprognostic (2.65e-1)" "unprognostic (1.33e-1)" "unprognostic (3.94e-2)" "unprognostic (1.15e-3)" "unprognostic (1.35e-1)" "unprognostic (3.22e-1)" "unprognostic (1.46e-2)" "unprognostic (1.04e-1)" 2.2 0.8 27.1 1.1 30.8 0.4 1.9 30.1 22.5 2.3 10.4 3.3 0.6 3.2 0.9 1.5 2.5 1.7 3.0 21.3 26.2 2.0 0.2 1.0 1.5 32.9 32.0 3.6 2.9 22.9 2.3 0.8 27.7 1.8 1.8 3.3 1.4 2.1 2.7 1.4 1.6 2.3 27.0 1.4 2.0 2.6 37.2 0.6 1.7 2.5 1.2 2.7 2.1 23.5 3.0 4.4 5.2 0.4 0.9 1.8 0.4 1.6 0.0 0.5 0.4 8.5 1.0 0.0 2.1 3.4 5.3 0.1 16.8 0.0 0.7 1.9 6.2 1.5 1.5 0.5 6.2 0.1 0.3 2.5 0.8 2.5 0.2 0.3 2.0 4.1 8.1 0.1 3.1 0.0 0.4 0.6 5.6 0.5 1.2 1.7 0.0 0.1 2.7 0.9 1.1 10.2 3.7 0.4 3.2 1.5 0.2 9.0 0.9 2.3 13.8 4.1 0.1 0.3 0.0 1.9 0.1 0.0 3.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 27.1 30.8 30.1 22.5 21.3 26.2 32.9 32.0 27.7 27.0 37.2 23.5 1.2 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 1.0 0.5 0.9 0.0 1.5 0.0 3.7 2.1 0.4 1.2 1.3 46.9 2.2 4.4 0.5 2.2 1.7 0.0 0.4 0.0 1.6 2.6 3.8 3.6 0.5 0.0 0.8 0.4 0.0 0.6 0.0 0.0 0.7 0.0 0.3 0.0 7.6 2.1 1.1 0.0 0.0 0.6 19.5 2.1 0.0 0.0 1.6 1.2 3.4 0.1 1.1 0.1 42.1 0.0 1.2 6.6 1.6 1.7 1.9 6.2 0.1 0.0 0.3 2.3 0.4 1.5 0.3 HADHA "GBP, LCEH, LCHAD, MTPA" ENSG00000084754 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha" P40939 2 26190635-26244672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 502.5" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 527.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015536, HPA056070" Approved Enhanced Mitochondria NA NA 470000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Mitochondria "HPA015536: AB_1850473, HPA056070: AB_2683026" "unprognostic (2.02e-1)" "unprognostic (1.38e-2)" "unprognostic (2.55e-1)" "unprognostic (3.43e-1)" "unprognostic (2.67e-2)" "unprognostic (3.23e-2)" "unprognostic (1.25e-2)" "unprognostic (2.02e-1)" "unprognostic (5.16e-2)" "unprognostic (3.45e-1)" "unprognostic (3.81e-1)" "unprognostic (1.16e-1)" "prognostic favorable (3.68e-5)" "unprognostic (7.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.87e-3)" "unprognostic (2.64e-2)" 105.0 125.3 57.7 31.1 60.7 46.3 94.9 65.0 69.6 72.6 59.1 108.4 115.0 61.8 30.7 90.1 60.1 32.4 330.2 52.8 61.9 99.0 156.7 66.9 35.3 64.4 62.2 77.8 101.4 95.0 57.4 39.2 64.2 60.2 76.1 14.9 77.9 33.4 502.5 95.7 106.2 57.4 61.8 68.4 93.8 49.0 62.4 46.7 59.5 300.7 58.5 79.1 73.6 67.2 105.7 88.1 58.4 90.8 221.1 139.9 51.5 80.6 84.7 78.5 67.7 114.7 104.1 71.7 50.2 138.4 78.6 66.8 103.4 152.6 72.5 139.1 103.6 103.3 86.2 197.9 73.3 132.2 69.2 142.7 101.6 112.4 109.3 82.8 127.7 70.4 140.2 133.2 101.1 128.2 63.4 137.7 50.1 77.5 134.1 52.9 128.5 143.7 90.3 125.3 41.9 85.1 94.6 104.6 102.4 44.5 52.2 125.8 127.1 48.8 70.7 69.9 58.0 44.8 86.5 113.4 77.6 150.2 56.2 22.5 84.0 33.5 31.8 92.3 39.1 40.5 36.8 38.7 80.8 31.2 42.6 40.1 20.9 38.8 86.1 31.3 50.9 89.9 57.7 60.7 65.0 69.6 52.8 61.9 64.4 62.2 64.2 61.8 62.4 67.2 122.4 89.8 99.0 47.0 101.2 89.0 137.5 139.9 97.3 35.6 89.7 96.4 349.9 82.9 128.0 77.3 52.1 182.0 95.1 242.1 131.0 120.8 39.2 73.3 121.1 99.1 91.4 155.9 22.8 108.5 94.7 96.1 100.4 85.5 139.9 140.3 84.3 185.1 163.0 20.2 28.2 156.5 89.5 136.8 106.0 74.3 92.6 145.0 81.8 12.2 170.7 65.4 93.7 30.7 37.4 90.0 195.6 84.2 90.4 76.2 527.4 182.5 84.8 62.3 52.6 129.9 109.6 147.9 54.9 136.5 103.3 129.2 100.5 154.7 216.7 104.4 HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 793.3;skeletal muscle: 950.6;tongue: 1097.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1167.5;Distal tubular cells: 520.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037539, HPA037540, HPA066099" Enhanced Supported Mitochondria No No 61000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA037539: AB_10671374, HPA037540: AB_2675531, HPA066099: AB_2685618" "unprognostic (5.15e-2)" "unprognostic (8.72e-2)" "unprognostic (8.21e-2)" "unprognostic (8.67e-2)" "unprognostic (7.70e-2)" "unprognostic (2.59e-2)" "unprognostic (7.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (2.03e-1)" "unprognostic (8.94e-2)" "prognostic favorable (1.37e-9)" "unprognostic (2.47e-1)" "unprognostic (2.50e-1)" "unprognostic (2.88e-1)" "unprognostic (9.68e-2)" 127.0 224.7 120.6 51.1 135.4 58.8 91.3 146.4 138.1 65.2 128.0 110.7 224.2 55.9 73.7 101.3 68.8 64.3 793.3 109.0 138.1 231.4 324.8 64.7 54.9 135.9 141.6 78.4 83.7 209.5 48.1 65.6 139.6 77.1 113.2 63.0 104.8 75.0 950.6 74.4 184.4 79.0 141.4 75.8 109.0 67.1 143.3 53.1 90.8 1097.1 62.5 89.2 64.1 152.8 108.2 83.2 56.6 102.2 342.1 190.1 57.9 89.0 134.6 89.0 86.8 100.5 101.7 53.9 60.8 145.3 100.1 82.8 95.2 124.8 109.2 121.1 83.1 123.6 44.9 194.2 145.9 100.6 90.0 183.7 201.6 92.7 149.0 151.0 168.2 81.0 105.2 83.9 189.5 78.0 57.1 190.7 39.8 160.2 89.0 61.7 188.3 103.2 183.3 148.9 27.2 93.7 151.7 169.8 239.5 68.5 105.4 177.9 118.0 83.5 86.9 79.3 65.1 62.6 101.1 94.7 95.5 158.4 84.4 95.7 168.1 66.4 45.2 150.3 57.6 65.5 61.3 56.6 154.2 49.7 55.8 51.3 72.7 88.2 123.3 51.8 94.7 135.6 120.6 135.4 146.4 138.1 109.0 138.1 135.9 141.6 139.6 141.4 143.3 152.8 106.5 48.1 36.5 63.0 48.3 62.1 136.5 183.3 49.5 29.3 49.5 52.3 1167.5 104.4 107.7 97.5 56.3 227.9 42.4 129.5 520.4 124.0 93.4 59.5 49.0 75.2 74.9 85.2 32.7 57.2 75.2 79.5 53.0 60.2 62.8 94.2 69.9 277.6 139.6 13.5 33.0 93.4 114.0 98.1 67.4 99.7 56.5 78.1 88.9 27.2 110.2 65.0 32.0 35.2 47.5 58.4 134.8 62.8 37.1 60.5 376.0 321.1 73.5 80.0 72.3 72.9 80.7 120.4 49.4 53.8 54.7 186.6 45.2 194.0 113.5 110.3 ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Astrocytes: 11.4;Early spermatids: 12.0;Late spermatids: 28.0;Microglial cells: 5.6;Oligodendrocytes: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 1.4;U-937: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" 0.1 0.1 0.5 0.4 0.3 0.4 0.0 1.0 0.6 0.0 0.5 0.1 0.5 0.1 0.0 0.2 0.1 0.1 0.0 0.4 0.4 0.8 0.1 0.1 0.5 0.6 0.3 0.2 0.8 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.3 0.3 0.2 0.5 0.4 0.4 0.2 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.5 0.0 0.1 0.8 0.1 0.0 0.0 0.1 0.2 0.0 1.0 0.6 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.7 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.0 0.0 1.4 0.4 0.9 0.0 0.0 0.8 0.7 0.3 0.0 1.1 0.8 0.4 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.3 0.1 0.7 0.7 1.2 0.0 1.4 0.1 0.0 0.0 0.4 0.2 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.3 1.0 0.6 0.4 0.4 0.6 0.3 0.4 0.3 0.4 0.4 0.4 0.0 0.0 11.4 1.3 0.0 0.3 0.0 0.0 0.9 0.3 0.4 0.7 0.0 0.0 0.0 2.1 0.1 0.8 0.0 0.0 0.1 12.0 0.9 1.1 0.2 0.0 0.0 3.4 0.0 0.1 0.2 0.5 0.8 0.0 0.2 0.0 0.2 0.1 1.7 4.1 0.1 0.0 0.0 0.0 28.0 0.0 0.5 0.0 5.6 0.3 0.2 0.0 3.0 6.3 0.1 0.0 0.0 2.7 0.1 0.4 0.1 0.0 1.2 0.0 0.2 0.3 1.5 0.4 0.1 0.0 0.1 0.9 0.2 0.2 0.1 SELENOI "EPT1, KIAA1724, SELI, SEPI" ENSG00000138018 "Selenoprotein I" Q9C0D9 2 26308547-26395891 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Endometrial ciliated cells: 16.3;Glandular and luminal cells: 15.3;Pancreatic endocrine cells: 13.6;Syncytiotrophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064125 Approved NA NA "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA064125: " "unprognostic (6.29e-2)" "unprognostic (7.46e-2)" "unprognostic (1.38e-3)" "unprognostic (3.05e-3)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "unprognostic (7.44e-3)" "unprognostic (5.00e-3)" "unprognostic (7.79e-2)" "unprognostic (2.55e-2)" "unprognostic (6.65e-2)" "unprognostic (9.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.76e-1)" "unprognostic (9.87e-3)" "unprognostic (1.42e-2)" 3.6 6.4 7.9 5.5 8.4 12.1 8.1 11.2 10.6 5.4 5.0 8.6 12.3 4.1 5.4 11.1 3.5 4.0 3.9 10.3 9.3 7.9 23.2 4.4 5.7 6.8 7.3 3.5 9.0 17.2 4.5 4.7 8.6 6.2 8.7 9.3 6.2 4.2 7.0 18.3 18.4 3.7 9.7 4.3 7.1 4.4 7.2 6.3 7.1 6.6 6.1 7.5 7.1 10.0 42.7 25.7 20.9 21.0 12.8 10.2 32.0 20.3 9.2 10.0 10.2 54.5 26.6 49.5 24.2 9.5 21.4 34.1 32.4 17.9 14.4 13.7 15.4 31.3 17.5 32.3 12.2 41.9 9.7 8.1 15.6 22.3 21.9 6.1 9.4 17.6 35.9 16.6 13.5 18.4 25.1 20.7 26.8 21.6 17.4 22.6 49.2 25.0 19.3 32.4 45.7 19.4 17.3 36.2 16.4 17.3 17.4 12.4 15.1 17.1 22.0 22.7 31.7 22.6 60.8 65.8 17.5 25.4 15.6 0.0 0.7 0.0 0.9 1.0 0.9 2.5 0.9 1.2 0.7 1.0 1.2 2.0 0.2 0.9 0.9 1.3 1.8 0.4 7.9 8.4 11.2 10.6 10.3 9.3 6.8 7.3 8.6 9.7 7.2 10.0 9.1 12.8 8.7 0.0 3.0 0.0 0.0 0.0 0.0 0.0 12.2 7.1 0.0 0.0 3.1 22.0 0.0 6.1 11.7 0.0 0.0 10.4 0.0 16.3 12.8 3.7 0.0 0.0 0.0 10.4 6.2 2.9 0.0 15.3 1.3 8.6 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 13.6 0.0 0.0 3.9 0.0 0.0 5.6 2.2 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 16.6 4.7 11.5 0.0 0.0 DRC1 "C2orf39, CCDC164, CILD21, FLJ32660, MGC16372" ENSG00000157856 "Dynein regulatory complex subunit 1" Q96MC2 2 26401920-26456711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.3;fallopian tube: 39.3;testis: 20.8" "Group enriched" "Detected in some" 5 "Early spermatids: 142.0;Endometrial ciliated cells: 112.8;Late spermatids: 321.2;Respiratory ciliated cells: 260.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "neutrophil: 8.9" "Lineage enriched" "Detected in single" 89 "granulocytes: 8.9" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "midbrain: 6.9" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.28e-3)" "unprognostic (2.68e-2)" "unprognostic (5.36e-2)" "unprognostic (5.27e-3)" "unprognostic (3.41e-3)" "unprognostic (8.56e-3)" "unprognostic (7.02e-4)" "unprognostic (1.45e-1)" "unprognostic (1.98e-1)" "unprognostic (7.26e-2)" "unprognostic (1.97e-3)" "unprognostic (2.99e-1)" "unprognostic (3.06e-3)" "unprognostic (8.19e-2)" "unprognostic (9.91e-3)" "unprognostic (2.16e-1)" "unprognostic (1.30e-2)" 0.0 0.0 2.3 0.0 2.5 0.7 0.0 1.4 1.4 1.5 10.3 0.1 0.0 0.9 0.1 0.0 39.3 0.0 0.0 2.1 2.8 0.2 0.0 3.1 0.0 5.7 7.3 0.0 0.0 0.0 3.2 0.0 4.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 20.8 2.9 0.3 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 2.3 2.5 1.4 1.4 2.1 2.8 5.7 7.3 4.5 5.0 2.9 4.9 0.2 0.0 1.1 1.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.3 0.5 0.0 17.9 1.8 0.0 0.0 0.0 0.1 0.0 0.0 142.0 112.8 1.2 0.3 0.0 0.0 4.3 0.7 0.0 0.5 0.0 1.5 1.3 0.0 0.0 0.0 0.1 0.0 4.8 0.1 10.2 0.0 0.0 321.2 2.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 1.2 0.4 0.0 0.2 1.3 0.1 260.8 0.0 0.0 0.0 2.4 39.5 1.8 0.0 0.0 0.0 0.2 0.0 0.1 0.0 OTOF "DFNB6, DFNB9, FER1L2" ENSG00000115155 Otoferlin Q9HC10 2 26457203-26558756 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Hearing "Deafness, Disease variant, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "bone marrow: 6.4;brain: 23.1" "Group enriched" "Detected in some" 4 "Inhibitory neurons: 4.0;Skeletal myocytes: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HDLM-2: 32.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012410 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "HPA012410: AB_1854836" "unprognostic (4.01e-3)" "unprognostic (7.85e-2)" "unprognostic (8.95e-2)" "unprognostic (7.20e-5)" "unprognostic (1.82e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (2.46e-1)" "unprognostic (6.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.26e-1)" "unprognostic (2.97e-3)" "unprognostic (4.85e-14)" "unprognostic (1.33e-2)" "unprognostic (5.19e-1)" "unprognostic (9.65e-2)" "unprognostic (8.96e-5)" 0.2 0.5 23.1 0.3 16.3 6.4 0.2 0.2 13.1 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.0 0.3 0.1 4.1 3.3 0.0 0.0 0.2 0.1 5.2 2.8 0.0 0.1 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.3 0.1 4.2 0.5 0.2 1.1 3.0 0.9 0.1 0.3 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 0.3 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 23.1 16.3 0.2 13.1 4.1 3.3 5.2 2.8 4.0 4.2 3.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.2 0.8 0.3 0.0 0.0 0.1 0.5 0.4 0.0 0.0 FAM166C "C2orf70, LOC339778" ENSG00000173557 "Family with sequence similarity 166 member C" A6NJV1 2 26562585-26579532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.6;testis: 26.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062453 Enhanced Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane, Vesicles" "HPA062453: AB_2684769" "unprognostic (5.44e-2)" "unprognostic (9.30e-3)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (1.99e-2)" "unprognostic (9.40e-6)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (6.49e-4)" "unprognostic (4.58e-2)" "unprognostic (1.52e-1)" "unprognostic (2.98e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-3)" "unprognostic (7.08e-3)" 0.1 0.1 0.8 0.1 0.7 0.0 0.2 0.5 0.6 0.3 4.1 0.6 0.1 0.2 0.3 0.1 7.6 0.0 0.4 0.8 2.5 1.0 0.0 0.4 0.0 2.0 2.0 0.0 0.7 0.1 0.7 0.0 1.2 0.2 0.4 0.1 1.9 0.2 0.1 0.1 0.1 0.1 1.5 0.0 4.8 26.6 2.9 0.0 1.1 0.0 0.0 0.1 0.0 1.0 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 3.7 0.0 0.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.5 0.6 0.8 2.5 2.0 2.0 1.2 1.5 2.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIB4 ENSG00000157884 "Calcium and integrin binding family member 4" A0PJX0 2 26581205-26641366 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 17.3" "Cell type enriched" "Detected in some" 7 "Early spermatids: 181.0" "Cancer enhanced" "Detected in some" "renal cancer: 0.7;thyroid cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA036130, HPA036131" Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA036130: AB_10670709, HPA036131: AB_2674959" "unprognostic (3.63e-3)" "unprognostic (1.78e-1)" "unprognostic (2.61e-4)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (4.29e-4)" "unprognostic (1.57e-1)" "unprognostic (3.19e-5)" "unprognostic (1.20e-2)" "unprognostic (3.63e-1)" "unprognostic (1.76e-3)" "unprognostic (3.50e-1)" 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.3 0.0 0.1 0.2 0.0 0.8 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.3 0.3 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.3 0.6 0.3 0.7 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 14.6 0.0 0.0 5.5 2.1 0.0 0.0 0.0 0.0 0.0 181.0 0.0 0.3 0.3 1.8 0.0 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 24.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 11.9 0.7 0.0 0.0 0.8 0.0 0.5 0.0 0.0 KCNK3 "K2p3.1, TASK, TASK-1, TASK1" ENSG00000171303 "Potassium two pore domain channel subfamily K member 3" O14649 2 26692690-26733420 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "adrenal gland: 181.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.1;Collecting duct cells: 103.0;Enteroendocrine cells: 23.4;Exocrine glandular cells: 95.2" "Cancer enhanced" "Detected in many" "renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.1;EFO-21: 11.0;HeLa: 3.6;SCLC-21H: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.16e-3)" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.67e-4)" "unprognostic (2.08e-1)" "unprognostic (2.91e-1)" "unprognostic (5.01e-2)" "unprognostic (2.16e-1)" "unprognostic (3.31e-1)" "unprognostic (5.48e-2)" "unprognostic (3.77e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.37e-7)" "unprognostic (3.09e-2)" "unprognostic (7.45e-2)" "unprognostic (1.44e-2)" "unprognostic (9.24e-3)" 3.8 181.6 5.1 1.3 4.4 0.1 2.9 4.9 6.0 8.4 0.0 5.5 1.2 6.3 1.5 2.1 4.0 1.2 13.1 3.0 14.3 2.7 0.5 25.7 0.1 27.0 19.3 2.1 35.5 12.1 8.4 24.8 26.8 6.3 0.9 3.3 0.4 3.3 0.8 0.7 2.4 2.7 5.4 1.1 4.2 0.6 10.4 0.1 3.6 0.0 0.0 4.2 2.8 3.9 0.0 0.7 0.2 0.0 5.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 11.0 0.0 1.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.4 0.0 25.9 2.3 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 5.1 4.4 4.9 6.0 3.0 14.3 27.0 19.3 26.8 5.4 10.4 3.9 0.3 0.0 2.8 0.3 0.1 0.0 0.2 0.3 0.0 82.1 0.2 3.6 12.7 0.0 0.0 103.0 0.0 0.2 0.1 0.0 0.0 1.0 0.4 0.3 7.7 1.2 23.4 0.0 2.1 95.2 0.2 2.7 0.0 0.2 0.0 1.2 0.4 0.0 0.4 1.7 14.5 1.8 0.0 0.0 0.9 1.9 0.9 0.3 0.0 0.0 0.6 1.4 0.0 1.5 0.3 19.2 0.0 0.0 0.3 1.6 0.1 0.1 0.0 4.1 6.6 0.6 4.9 0.0 1.5 0.0 0.1 0.5 0.4 11.5 0.1 0.4 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 CENPA "CenH3, CENP-A" ENSG00000115163 "Centromere protein A" P49450 2 26764289-26801067 "Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.0;Extravillous trophoblasts: 33.2;Granulosa cells: 24.2;Plasma cells: 17.8;Spermatogonia: 28.6" "Cancer enhanced" "Detected in many" "testis cancer: 24.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB008371, HPA073086" Enhanced Supported Nucleoplasm NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB008371: AB_591074, HPA073086: AB_2686569" "unprognostic (3.94e-2)" "unprognostic (1.38e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.13e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (2.88e-8)" "prognostic unfavorable (3.70e-4)" "unprognostic (1.69e-3)" "unprognostic (7.80e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (4.21e-3)" "unprognostic (0.00e+0)" "unprognostic (5.74e-2)" "unprognostic (1.33e-1)" "unprognostic (7.68e-2)" "unprognostic (2.07e-1)" 0.2 0.3 0.0 4.0 0.0 3.7 0.4 0.1 0.1 0.5 0.0 2.9 4.1 0.7 0.0 3.7 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.4 7.3 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.1 2.6 0.0 0.6 0.0 0.0 3.6 2.9 0.9 0.0 2.0 1.6 2.2 0.1 13.3 0.1 0.0 8.4 0.7 1.1 0.0 86.4 21.0 34.9 19.3 2.4 4.5 24.3 26.2 22.2 37.3 31.5 15.4 30.0 25.7 16.2 10.4 45.7 25.6 28.9 15.3 37.7 77.3 25.6 44.0 11.0 28.6 0.8 26.7 49.0 0.4 1.6 16.1 24.4 6.7 22.1 33.7 36.7 58.5 32.5 30.1 39.0 42.2 26.6 35.3 34.3 45.4 53.6 30.8 17.5 5.5 27.5 26.7 25.7 32.7 23.6 12.9 18.2 27.2 12.6 23.9 54.2 27.9 46.4 51.5 53.5 107.3 11.1 54.7 46.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 5.2 6.2 0.7 1.9 1.8 0.0 2.0 2.5 2.7 0.0 0.5 0.0 0.0 15.3 1.0 2.3 0.0 0.5 0.6 1.6 1.6 1.5 4.2 45.0 0.1 0.2 33.2 4.9 2.6 3.0 0.0 24.2 3.9 0.6 15.7 0.0 0.1 6.6 0.0 2.9 2.8 0.1 0.9 4.4 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.1 1.4 0.0 17.8 2.1 0.8 0.2 0.1 0.0 0.0 0.6 3.9 16.1 28.6 12.5 5.3 3.4 3.4 1.5 11.1 2.0 DPYSL5 "CRAM, CRMP-5, CRMP5, CV2, Ulip6" ENSG00000157851 "Dihydropyrimidinase like 5" Q9BPU6 2 26847747-26950351 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 111.5" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 85.5;Late spermatids: 134.3;Oligodendrocytes: 331.2" "Group enriched" "Detected in some" 15 "glioma: 17.7;testis cancer: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 141.0;HAP1: 118.7;SCLC-21H: 167.3;SH-SY5Y: 99.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034544, HPA072387" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Cytosol "HPA034544: AB_10671228, HPA072387: AB_2686516" "unprognostic (1.07e-4)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (3.64e-6)" "unprognostic (3.94e-1)" "unprognostic (6.21e-2)" "unprognostic (6.12e-2)" "unprognostic (2.66e-1)" "unprognostic (1.54e-1)" "unprognostic (3.54e-2)" "unprognostic (1.35e-1)" "unprognostic (1.77e-2)" "unprognostic (5.67e-3)" "unprognostic (3.62e-2)" "unprognostic (1.08e-1)" "unprognostic (2.43e-1)" 0.0 1.9 22.6 0.3 49.4 0.0 0.0 59.4 41.7 0.1 3.8 0.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 17.6 42.1 0.1 0.0 0.0 0.0 79.6 50.2 0.1 0.0 0.0 7.8 0.0 65.5 0.1 0.2 15.8 0.0 0.0 0.1 0.0 0.3 0.3 54.8 0.0 0.1 7.8 60.2 0.0 0.0 0.0 0.0 0.0 0.1 111.5 0.0 3.0 141.0 0.1 0.6 0.0 3.3 0.0 0.0 0.0 0.0 13.2 0.0 0.0 1.0 0.0 3.9 0.0 118.7 0.0 0.0 0.0 26.2 0.0 0.1 0.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 31.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 167.3 99.0 3.8 0.2 0.0 3.3 0.0 0.0 0.0 0.0 4.1 0.1 3.8 0.0 5.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.6 49.4 59.4 41.7 17.6 42.1 79.6 50.2 65.5 54.8 60.2 111.5 0.1 0.0 0.0 13.4 0.1 0.0 0.3 0.0 0.0 12.1 0.1 0.0 6.0 0.0 0.0 0.0 85.5 0.1 0.0 0.0 0.0 0.0 45.6 0.1 0.1 0.4 0.0 0.0 18.3 0.0 0.0 0.3 0.0 0.2 2.5 0.2 0.0 0.2 0.1 8.4 40.5 0.0 0.0 0.0 0.7 134.3 1.5 0.2 1.8 2.8 0.1 17.2 0.0 18.1 331.2 0.0 0.0 1.2 0.1 0.2 0.0 0.1 0.0 12.1 0.0 0.7 0.3 2.9 4.6 0.0 0.3 0.0 0.2 0.7 0.0 0.1 MAPRE3 "EB3, RP3" ENSG00000084764 "Microtubule associated protein RP/EB family member 3" Q9UPY8 2 26970637-27027219 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 146.6" "Group enriched" "Detected in many" 5 "Early spermatids: 428.2;Late spermatids: 311.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 69.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009263 Uncertain NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "HPA009263: AB_1078716" "unprognostic (1.24e-1)" "unprognostic (1.10e-1)" "unprognostic (8.31e-2)" "unprognostic (2.94e-2)" "unprognostic (1.04e-2)" "unprognostic (3.40e-2)" "unprognostic (2.22e-2)" "unprognostic (1.35e-3)" "unprognostic (1.75e-2)" "unprognostic (3.49e-1)" "unprognostic (4.77e-3)" "unprognostic (2.37e-1)" "unprognostic (1.22e-2)" "unprognostic (3.84e-2)" "unprognostic (3.43e-1)" "unprognostic (2.48e-1)" "unprognostic (2.30e-1)" 24.0 23.1 100.7 7.3 102.4 1.3 23.6 73.5 133.2 26.6 50.8 25.4 7.2 24.8 10.4 12.2 42.2 12.6 45.2 108.8 105.2 30.4 37.6 17.8 5.9 94.4 82.9 46.1 14.7 36.8 101.7 10.8 98.1 26.1 9.8 70.5 18.3 15.0 146.6 43.3 10.5 12.9 66.5 15.8 23.2 56.4 107.0 7.6 24.4 56.8 6.5 22.0 19.0 95.8 19.8 15.2 13.6 24.0 24.4 13.5 3.9 15.3 12.2 12.7 12.9 5.7 25.8 0.0 14.4 19.1 33.5 10.1 7.6 16.3 7.5 16.5 18.7 2.9 8.1 1.3 22.4 2.3 36.5 11.1 28.5 6.4 11.9 34.6 3.1 1.7 19.4 15.1 7.7 9.0 0.1 1.0 6.0 69.2 23.9 0.1 0.3 2.0 8.8 13.0 34.4 17.0 10.6 7.5 11.0 8.9 8.0 1.4 3.3 11.1 11.4 16.0 13.7 11.5 4.4 0.1 39.9 1.5 22.6 0.2 1.3 0.3 0.7 1.4 0.4 0.6 0.3 0.2 0.8 0.3 0.5 0.1 3.5 0.5 1.7 0.0 0.1 0.7 100.7 102.4 73.5 133.2 108.8 105.2 94.4 82.9 98.1 66.5 107.0 95.8 13.7 3.2 2.8 25.8 2.6 8.8 21.8 15.2 11.4 44.0 6.4 8.8 8.3 5.7 6.6 3.7 25.0 1.4 1.6 32.3 17.6 11.5 428.2 64.7 11.2 5.5 25.1 2.5 43.7 4.6 4.6 11.2 11.2 4.1 38.1 13.8 14.3 8.6 2.1 58.9 45.0 1.9 18.3 2.8 4.5 311.4 12.8 4.6 7.2 5.6 0.8 69.3 4.1 26.2 27.4 12.0 8.4 11.7 2.7 9.6 0.2 6.8 48.8 44.6 32.9 10.2 14.0 21.0 14.4 6.5 13.8 18.9 3.4 38.6 3.0 15.0 TMEM214 FLJ20254 ENSG00000119777 "Transmembrane protein 214" Q6NUQ4 2 27032910-27041694 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034551 Supported "Endoplasmic reticulum,Golgi apparatus,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Cytosol" "HPA034551: AB_10602481" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.10e-1)" "unprognostic (4.12e-3)" "unprognostic (1.90e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.96e-4)" "unprognostic (1.96e-1)" "unprognostic (3.70e-1)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.74e-2)" "prognostic unfavorable (2.39e-10)" "unprognostic (1.54e-2)" "unprognostic (1.97e-2)" "unprognostic (2.04e-1)" "unprognostic (2.92e-2)" 45.8 39.0 14.7 30.8 15.8 23.1 43.2 15.3 17.3 45.0 28.7 38.3 30.5 43.7 66.2 31.5 37.5 30.7 36.7 14.8 17.0 30.0 46.5 37.7 25.1 19.1 18.7 41.4 79.9 56.0 60.4 45.8 18.3 37.9 41.7 8.8 83.6 44.4 35.7 37.8 33.6 45.1 15.6 37.4 40.8 19.5 17.8 21.7 42.3 21.3 34.4 36.7 33.9 14.9 82.4 53.5 32.2 68.2 102.8 103.7 69.4 105.9 142.4 76.0 85.2 53.0 67.3 37.6 52.4 156.6 59.7 57.6 39.3 74.9 61.0 36.3 44.1 49.9 41.4 109.8 128.1 45.7 82.5 90.4 52.7 66.8 112.0 58.6 83.5 24.3 46.0 75.3 85.9 59.6 23.3 34.1 23.1 110.0 42.8 31.3 58.5 91.0 57.1 57.0 27.8 32.3 49.4 83.3 38.2 31.0 45.9 27.0 72.4 55.2 52.8 57.0 60.4 100.9 73.3 59.2 71.1 56.8 77.9 5.7 3.5 2.8 3.9 3.8 5.0 2.5 3.0 2.8 2.8 2.8 1.5 2.1 0.6 5.6 2.2 5.0 2.6 2.5 14.7 15.8 15.3 17.3 14.8 17.0 19.1 18.7 18.3 15.6 17.8 14.9 15.8 3.2 20.1 3.9 18.5 7.6 9.6 10.4 3.4 9.3 19.8 11.0 8.2 21.5 15.0 14.7 10.4 43.6 15.0 37.5 1.9 24.7 6.4 11.3 25.4 17.5 17.9 18.5 4.8 34.6 62.9 26.9 33.1 23.8 14.5 17.0 32.5 28.9 27.3 6.7 4.4 37.6 10.2 18.9 12.8 7.8 32.6 11.7 5.4 6.5 14.6 6.9 14.4 4.0 3.8 21.7 22.3 20.3 63.0 20.8 25.4 10.4 11.0 8.4 26.3 11.6 19.6 24.4 12.7 8.4 9.2 71.7 12.0 17.6 27.6 15.8 AGBL5 "CCP5, FLJ21839" ENSG00000084693 "ATP/GTP binding protein like 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 49.9;testis: 192.9" "Group enriched" "Detected in many" 6 "Early spermatids: 302.7;Late spermatids: 338.0;Spermatocytes: 156.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030981 Uncertain Supported "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Cytokinetic bridge" "Microtubules, Cytosol" "HPA030981: AB_10611673" "unprognostic (1.29e-2)" "unprognostic (8.70e-2)" "unprognostic (2.26e-1)" "unprognostic (3.13e-3)" "unprognostic (1.95e-1)" "unprognostic (1.07e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.86e-1)" "unprognostic (4.34e-1)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-2)" "unprognostic (5.56e-2)" "unprognostic (2.05e-1)" "unprognostic (1.69e-2)" "unprognostic (4.50e-2)" 8.8 16.7 8.4 8.0 7.4 13.6 12.4 7.8 8.2 14.4 9.5 16.2 8.8 14.0 26.0 18.3 20.8 14.3 12.7 7.3 11.3 22.5 7.2 11.2 10.7 8.3 7.8 14.4 15.0 49.9 12.5 11.2 8.9 15.2 11.5 16.3 21.2 16.5 7.1 20.5 9.9 14.6 6.1 8.5 11.8 192.9 9.1 15.6 28.5 6.5 8.6 14.9 7.3 7.5 55.0 34.7 55.4 37.2 11.6 23.0 62.9 10.9 23.5 30.9 31.9 30.2 40.5 30.3 34.0 18.9 43.4 24.6 44.8 49.4 33.9 25.9 66.8 44.5 42.0 65.7 23.6 21.6 14.4 24.4 36.7 27.1 22.0 46.9 32.8 43.5 38.9 23.8 30.3 21.5 63.2 32.3 39.4 39.4 23.7 64.5 62.9 48.0 31.9 13.6 37.1 53.6 21.5 16.7 35.0 53.9 24.9 16.3 16.4 28.6 39.2 13.8 23.9 47.7 27.2 62.4 31.8 24.4 26.1 8.8 1.8 4.5 3.3 1.1 2.5 4.6 4.1 4.6 4.1 2.3 3.6 2.2 1.1 8.5 0.7 2.3 2.8 3.8 8.4 7.4 7.8 8.2 7.3 11.3 8.3 7.8 8.9 6.1 9.1 7.5 3.6 0.0 10.1 5.2 6.3 3.3 8.3 7.2 13.6 5.7 8.6 6.7 6.7 10.0 6.8 9.2 0.0 14.7 1.8 5.9 19.6 8.3 302.7 13.0 3.9 4.9 2.4 11.6 7.9 6.0 7.9 6.4 5.6 5.8 1.3 14.1 6.4 4.1 5.2 0.0 9.1 8.4 6.1 3.1 3.5 338.0 10.5 8.0 7.2 6.5 4.9 6.8 0.0 10.1 10.1 5.0 7.6 11.3 17.1 6.0 6.3 25.0 10.7 10.0 0.0 4.2 7.0 156.8 41.2 16.3 2.7 8.3 5.0 9.4 8.6 10.5 OST4 ENSG00000228474 "Oligosaccharyltransferase complex subunit 4, non-catalytic" P0C6T2 2 27070472-27071654 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 32: Non-specific - Translation" "unprognostic (5.15e-2)" "unprognostic (4.42e-2)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (5.95e-2)" "unprognostic (1.95e-3)" "prognostic unfavorable (5.11e-4)" "unprognostic (2.66e-1)" "unprognostic (1.18e-1)" "unprognostic (2.88e-2)" "unprognostic (7.89e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (7.35e-5)" "unprognostic (1.33e-1)" "unprognostic (8.52e-2)" "unprognostic (1.38e-1)" "unprognostic (9.88e-2)" 302.0 323.9 359.4 276.6 368.6 446.0 288.7 370.1 440.9 365.2 371.6 366.6 255.3 214.6 458.9 268.4 258.6 297.8 541.4 357.5 387.2 313.6 392.9 220.8 370.4 373.4 375.4 329.2 295.3 377.2 169.0 232.2 375.8 268.4 327.6 146.3 411.8 320.7 396.9 211.7 298.1 325.7 375.9 260.8 269.2 137.9 371.6 443.2 277.0 534.2 352.1 480.9 231.8 387.8 526.7 444.8 492.1 336.3 1362.9 1154.9 327.7 635.8 749.7 386.9 559.9 450.5 435.2 248.4 427.1 1044.1 572.4 244.1 321.3 701.9 305.9 486.4 491.5 527.4 300.4 1082.4 769.3 386.5 465.7 1235.3 591.0 509.8 468.3 952.9 916.5 490.1 337.2 509.8 882.5 641.8 472.7 710.4 293.7 1029.8 695.8 274.1 543.6 617.9 906.6 577.2 289.7 660.5 337.8 541.2 469.8 622.6 294.5 449.5 683.7 541.5 461.0 409.5 449.6 835.8 720.7 893.5 551.9 427.2 466.0 3182.5 1405.3 2129.1 1337.7 1230.8 1558.0 1748.5 1752.0 1469.2 1341.1 1473.3 1607.2 1551.1 1133.7 1049.8 1221.4 2614.4 1818.9 4735.8 359.4 368.6 370.1 440.9 357.5 387.2 373.4 375.4 375.8 375.9 371.6 387.8 370.4 176.3 301.9 13.7 522.3 411.2 417.7 1106.0 233.9 58.1 754.0 1020.4 369.3 377.4 595.2 663.9 20.9 527.6 555.4 597.3 1195.4 611.5 211.3 296.4 453.3 395.7 435.1 465.9 4.7 661.7 841.8 394.3 215.6 561.8 460.2 316.1 616.8 808.5 843.3 33.7 6.1 993.1 573.7 569.5 600.1 142.5 504.2 577.1 597.7 6.5 1041.6 309.1 632.4 9.5 13.5 668.3 725.3 429.1 749.7 509.8 1012.6 1348.1 310.0 81.8 295.9 230.7 492.5 242.3 392.6 424.9 589.0 577.1 532.4 299.2 669.3 620.6 EMILIN1 "DKFZp586M121, gp115" ENSG00000138080 "Elastin microfibril interfacer 1" Q9Y6C2 2 27078615-27086403 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 64.5;Fibroblasts: 111.3;Hepatic stellate cells: 45.0;Leydig cells: 85.1;Peritubular cells: 167.3;Sertoli cells: 72.3;Smooth muscle cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 98.2;BJ hTERT+: 65.0;HHSteC: 99.0;HSkMC: 109.6;SH-SY5Y: 129.4;U-138 MG: 63.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002822 Supported "Secreted to extracellular matrix" NA NA 4300000 "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA002822: AB_1078738" "unprognostic (3.14e-1)" "unprognostic (2.44e-2)" "unprognostic (3.92e-2)" "unprognostic (3.42e-2)" "unprognostic (3.26e-2)" "unprognostic (1.46e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-2)" "unprognostic (4.10e-3)" "unprognostic (3.07e-2)" "unprognostic (1.85e-1)" "unprognostic (7.97e-2)" "prognostic unfavorable (8.13e-9)" "unprognostic (8.96e-3)" "unprognostic (3.77e-2)" "unprognostic (1.20e-2)" "unprognostic (5.70e-3)" 55.5 55.7 6.9 47.0 7.1 1.9 43.6 6.4 7.1 139.8 4.6 223.5 24.9 206.3 7.4 23.3 129.2 35.4 68.9 5.9 7.5 55.5 42.4 100.7 11.7 13.0 7.6 172.4 21.2 1.4 26.9 16.2 9.5 96.4 7.9 0.3 17.5 52.1 10.3 19.1 72.0 50.3 8.3 118.1 87.6 16.9 10.4 2.4 29.7 2.6 2.2 142.9 70.2 8.6 0.9 0.7 5.9 0.9 35.8 49.0 1.1 98.2 65.0 20.7 29.7 0.5 0.8 0.6 0.9 56.6 0.1 0.9 0.2 0.2 3.8 3.1 1.3 1.8 0.5 43.9 99.0 1.5 27.0 109.6 0.1 14.2 0.0 0.2 0.2 1.3 1.0 0.9 4.3 1.1 0.9 28.8 3.2 0.5 0.7 15.6 1.3 1.2 0.0 0.4 1.6 129.4 0.3 0.5 1.1 0.4 0.4 2.5 11.9 63.6 2.0 7.6 0.4 1.7 1.8 1.1 0.7 1.3 17.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 6.9 7.1 6.4 7.1 5.9 7.5 13.0 7.6 9.5 8.3 10.4 8.6 5.2 0.0 0.5 6.5 0.4 3.3 0.2 0.0 0.0 0.6 0.8 7.1 2.9 1.5 0.0 0.0 0.0 1.6 0.6 0.2 0.0 0.4 0.6 1.9 64.5 6.3 0.0 4.0 0.2 0.4 1.5 111.3 0.5 1.3 4.5 0.2 45.0 1.0 6.4 0.0 0.3 0.3 0.0 2.5 5.8 10.0 85.1 4.1 10.6 8.4 0.5 3.6 0.0 0.5 0.3 0.8 0.1 167.3 0.8 0.2 0.5 1.0 0.0 1.1 72.3 35.3 52.4 0.6 0.4 0.4 3.1 2.9 1.3 10.7 0.1 0.1 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "intestine: 121.2;kidney: 104.4;liver: 180.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 428.5;Proximal enterocytes: 1858.7;Proximal tubular cells: 1019.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 32.8;Hep G2: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 2.2 4.6 4.2 3.0 4.3 1.7 2.0 7.1 5.9 2.6 1.2 4.2 112.4 3.8 0.6 2.4 4.3 1.3 1.4 4.8 3.9 104.4 180.5 1.6 1.9 5.4 4.0 3.6 9.4 2.6 1.4 0.5 5.5 1.6 1.2 1.5 4.4 1.4 3.8 2.4 121.2 1.9 3.6 2.0 2.9 3.2 3.8 0.7 1.1 2.0 1.2 1.8 2.3 4.7 25.0 18.5 2.8 11.0 2.0 0.5 2.5 1.7 1.1 2.3 1.4 9.0 5.3 3.7 5.8 0.1 2.6 10.7 9.4 3.1 0.8 8.8 17.2 32.8 5.2 48.0 1.1 4.6 3.7 0.1 1.3 2.7 0.2 1.2 2.1 5.1 5.9 6.1 0.2 16.0 5.4 3.6 4.0 22.3 7.2 18.9 1.4 20.9 2.7 3.0 10.2 15.8 3.6 6.2 6.9 1.0 2.7 2.0 1.9 0.7 3.6 1.6 6.5 7.5 14.4 6.3 3.0 10.7 1.8 0.0 5.4 0.3 4.1 3.1 5.5 3.8 6.6 6.0 4.9 3.6 4.7 5.8 0.5 4.9 1.4 6.1 4.7 4.9 4.2 4.3 7.1 5.9 4.8 3.9 5.4 4.0 5.5 3.6 3.8 4.7 6.5 3.2 3.7 1.6 6.8 3.6 2.6 0.8 6.8 3.6 4.7 5.8 1.8 20.0 1.0 40.5 2.1 4.1 1.3 7.4 129.1 3.2 1.2 0.1 0.6 5.5 6.0 15.6 3.4 3.0 3.6 2.4 3.6 0.3 4.5 2.9 9.7 428.5 8.3 6.7 2.7 89.6 4.1 11.9 2.0 6.2 1.8 10.8 8.8 0.0 1.9 9.8 4.1 2.5 2.3 2.1 95.7 1.5 8.0 0.7 1858.7 1019.7 0.0 5.4 0.0 5.0 5.0 1.1 5.8 4.6 6.8 9.4 6.8 0.8 82.6 2.2 CGREF1 CGR11 ENSG00000138028 "Cell growth regulator with EF-hand domain 1" Q99674 2 27098889-27119128 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;salivary gland: 25.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.6;Excitatory neurons: 16.6;Inhibitory neurons: 15.9;Oligodendrocyte precursor cells: 12.5;Spermatogonia: 16.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 40.1;SK-BR-3: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008241, HPA071103" Uncertain Approved "Golgi apparatus" "Secreted in brain" NA NA 700000 "Cluster 65: Brain - Ion transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA008241: AB_1846605, HPA071103: " "unprognostic (1.39e-2)" "unprognostic (1.26e-2)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.18e-4)" "unprognostic (8.45e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (7.57e-4)" "unprognostic (5.22e-2)" "unprognostic (7.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.57e-1)" "unprognostic (2.27e-1)" "unprognostic (2.52e-3)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (7.24e-4)" "unprognostic (1.20e-2)" 4.2 2.3 20.4 1.0 21.7 1.9 6.3 17.1 28.3 3.5 2.1 2.6 3.9 11.6 1.4 3.5 12.4 3.9 4.9 27.0 18.1 3.8 14.9 1.1 0.5 12.8 12.1 13.9 2.1 0.2 3.3 0.3 12.8 4.2 3.8 3.7 25.3 0.9 6.5 2.3 5.6 5.4 10.2 0.6 11.4 3.8 17.2 0.2 1.8 6.9 0.4 3.7 1.5 16.4 7.6 6.3 0.3 8.1 18.3 6.8 0.7 9.1 0.0 0.8 0.4 1.7 6.2 0.1 2.4 18.2 2.2 0.4 1.4 2.1 0.5 0.7 3.7 0.1 10.4 16.4 16.9 5.3 0.6 4.7 18.1 2.6 2.1 11.6 0.7 1.3 0.2 0.4 1.2 24.0 4.0 6.8 2.1 40.1 16.8 0.3 0.0 0.6 0.1 0.3 17.8 26.6 17.7 78.7 9.4 0.2 25.3 13.3 0.0 0.0 6.9 0.0 0.7 2.3 0.8 0.7 0.0 0.2 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.7 17.1 28.3 27.0 18.1 12.8 12.1 12.8 10.2 17.2 16.4 0.1 0.0 0.0 2.6 0.4 0.6 0.2 0.0 1.8 9.2 9.2 12.6 1.4 0.0 0.0 0.0 4.2 0.0 0.1 0.2 0.0 0.1 1.1 0.3 3.0 0.4 0.0 5.5 16.6 1.5 0.2 3.8 4.6 0.1 0.0 0.4 3.6 5.0 0.4 0.0 15.9 6.8 0.0 0.6 0.7 3.1 4.4 0.2 0.0 1.9 0.0 0.5 0.0 12.5 0.8 2.1 0.0 8.6 1.1 1.8 3.4 4.4 0.0 2.2 0.0 1.7 0.7 3.2 16.2 2.2 0.4 0.1 0.1 3.2 0.9 0.1 ABHD1 "FLJ36128, LABH1" ENSG00000143994 "Abhydrolase domain containing 1" Q96SE0 2 27123789-27130812 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 21.6" "Group enriched" "Detected in many" 9 "Early spermatids: 295.1;Late spermatids: 1030.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.5;T-47d: 3.3;U-266/70: 3.0;U-266/84: 2.8" "Low region specificity" "Detected in all" HPA044390 Uncertain NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA044390: AB_10959380" "unprognostic (1.20e-3)" "unprognostic (6.07e-3)" "unprognostic (7.71e-4)" "unprognostic (1.63e-2)" "unprognostic (6.68e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-3)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (9.09e-4)" "unprognostic (9.76e-2)" "unprognostic (1.70e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-2)" "unprognostic (3.09e-2)" "unprognostic (7.97e-2)" 1.2 0.6 0.8 0.1 0.7 0.0 0.5 1.5 1.1 0.1 0.3 0.1 0.0 0.3 0.4 0.1 0.2 0.2 0.5 0.7 0.8 0.3 3.3 0.1 0.2 0.9 0.7 0.4 0.1 0.4 0.2 0.0 0.9 0.7 0.0 0.4 1.5 0.2 1.9 0.0 0.1 0.3 0.9 0.1 0.2 21.6 0.9 0.0 0.4 1.7 0.1 0.0 0.0 0.9 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.0 0.0 1.5 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.2 3.0 2.8 0.0 0.1 0.1 0.1 0.0 0.2 0.8 0.6 0.0 0.2 0.5 0.3 0.3 0.0 0.3 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.8 0.7 1.5 1.1 0.7 0.8 0.9 0.7 0.9 0.9 0.9 0.9 0.8 0.0 0.0 4.9 1.0 0.0 3.3 0.0 2.8 5.1 1.9 2.8 3.1 1.5 0.0 0.0 8.4 0.2 0.9 0.2 0.0 0.3 295.1 0.4 0.6 1.9 0.0 3.2 0.6 0.2 0.0 1.3 0.0 0.5 1.3 1.6 2.5 3.9 0.1 0.0 0.8 0.2 0.0 0.3 0.3 1030.5 6.5 1.2 0.0 1.9 0.5 8.1 3.1 2.0 2.2 0.0 0.0 5.7 0.5 3.6 0.2 3.0 0.7 4.9 0.0 2.4 1.2 70.5 3.9 0.3 0.3 0.0 1.8 0.3 0.2 2.2 PREB SEC12 ENSG00000138073 "Prolactin regulatory element binding" Q9HCU5 2 27130756-27134666 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 101.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 369.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013582, HPA014133" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "HPA013582: AB_1855694, HPA014133: AB_1855695" "unprognostic (2.32e-1)" "unprognostic (2.11e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.01e-2)" "unprognostic (1.21e-2)" "unprognostic (4.96e-3)" "unprognostic (1.44e-1)" "unprognostic (9.89e-2)" "unprognostic (1.21e-3)" "unprognostic (1.24e-2)" "unprognostic (2.69e-1)" "unprognostic (2.33e-3)" "unprognostic (5.13e-2)" "unprognostic (4.14e-2)" "unprognostic (5.25e-2)" "unprognostic (1.28e-2)" 45.2 46.0 40.0 28.6 41.4 16.5 39.5 41.5 47.9 38.7 37.3 34.0 27.7 57.3 104.8 41.0 46.1 25.9 62.5 42.0 42.6 49.0 137.2 33.4 33.3 44.2 41.4 49.9 73.9 30.8 42.8 22.6 41.4 42.7 27.7 16.7 60.0 34.6 134.5 29.6 36.0 40.7 41.8 51.5 42.5 35.1 42.1 31.0 30.3 112.0 38.3 34.9 32.3 42.6 63.5 62.2 35.4 56.5 84.8 30.2 65.8 44.6 46.5 63.5 44.4 59.1 38.7 78.3 45.9 44.5 68.7 35.3 70.3 56.3 41.3 58.7 63.2 64.2 30.7 128.3 111.1 74.3 58.2 28.8 67.5 60.2 68.2 34.2 44.7 61.4 48.0 68.3 57.6 73.4 69.2 56.5 37.2 81.5 64.8 63.9 70.9 369.2 46.9 33.2 79.8 42.8 42.8 88.3 65.7 36.1 39.4 125.3 25.0 33.9 48.7 29.8 51.0 150.5 67.9 95.1 56.4 83.4 65.4 73.7 61.0 103.3 50.4 52.2 53.7 44.5 42.1 50.2 62.5 43.9 40.1 41.7 25.4 65.0 55.8 74.1 50.9 63.9 40.0 41.4 41.5 47.9 42.0 42.6 44.2 41.4 41.4 41.8 42.1 42.6 9.7 16.0 12.7 5.5 33.5 18.0 9.8 14.3 9.1 12.2 21.8 19.0 14.2 20.0 10.6 20.2 12.5 45.3 22.8 17.3 35.2 29.8 5.9 5.8 14.7 10.8 8.4 30.7 7.4 35.1 60.3 18.2 28.1 11.9 23.6 13.1 16.1 36.1 38.0 6.7 7.7 28.5 20.3 19.8 16.3 9.1 23.6 17.9 19.6 8.4 16.6 25.3 24.7 9.5 9.1 30.9 20.4 44.8 101.5 18.4 30.0 29.2 3.8 10.9 32.9 10.2 21.0 32.1 44.8 18.7 17.3 77.4 22.6 16.2 22.3 12.9 PRR30 "C2orf53, MGC44505" ENSG00000186143 "Proline rich 30" Q53SZ7 2 27136848-27139410 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1006 "testis: 147.6" "Group enriched" "Detected in some" 48 "Early spermatids: 646.9;Late spermatids: 773.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (5.60e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 646.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 773.6 5.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCF23 "bHLHa24, OUT" ENSG00000163792 "Transcription factor 23" Q7RTU1 2 27149004-27156974 "Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 51.2;fallopian tube: 24.6;ovary: 18.5;smooth muscle: 20.4" "Cell type enhanced" "Detected in some" "Leydig cells: 10.5;Peritubular cells: 29.0;Sertoli cells: 52.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 12 "THP-1: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044596 Approved "Nuclear speckles" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear speckles" "HPA044596: AB_10797258" "unprognostic (1.04e-1)" "unprognostic (2.47e-3)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (3.65e-2)" "unprognostic (2.68e-2)" "unprognostic (1.70e-2)" "unprognostic (4.07e-2)" "unprognostic (3.21e-1)" "unprognostic (1.74e-2)" "unprognostic (4.08e-2)" "unprognostic (8.58e-2)" "unprognostic (2.41e-5)" "unprognostic (7.58e-3)" "unprognostic (3.01e-1)" "unprognostic (8.58e-4)" "unprognostic (2.64e-2)" 0.4 0.0 0.2 0.0 0.2 0.2 0.0 0.5 0.4 4.6 0.2 0.2 0.1 51.2 5.8 0.0 24.6 0.7 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.1 18.5 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.5 0.2 0.1 0.1 20.4 0.0 2.3 0.1 2.6 0.2 0.0 0.0 0.0 0.0 0.2 2.9 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.2 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.4 0.3 0.2 1.1 0.3 0.1 0.4 0.1 0.0 0.2 0.2 0.5 0.4 0.3 0.2 0.1 0.1 0.3 0.0 0.2 0.5 0.1 0.0 2.2 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.3 0.3 0.7 0.0 0.6 0.0 2.1 0.0 0.2 0.1 0.0 0.0 1.7 0.2 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 1.3 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 10.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.7 0.0 0.1 0.0 0.6 52.6 1.0 1.5 0.3 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.6 SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.1;Extravillous trophoblasts: 111.7;Hepatocytes: 67.7;Syncytiotrophoblasts: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 310.9;SK-BR-3: 337.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" 42.4 8.6 27.5 14.2 25.2 18.1 31.5 24.0 30.6 9.4 46.2 13.0 20.9 14.3 67.4 10.9 11.5 7.5 7.7 23.4 23.9 8.5 104.0 7.9 13.8 24.0 24.4 10.2 11.6 9.8 8.0 39.1 25.9 9.3 12.7 6.4 12.5 11.1 17.0 10.0 15.3 9.7 23.9 9.1 10.1 23.4 30.6 11.6 8.0 8.8 26.5 11.3 8.8 21.9 78.9 79.6 49.9 66.1 45.4 16.5 310.9 28.1 19.1 41.8 28.7 118.8 27.0 54.2 41.3 15.4 44.7 42.8 108.3 32.4 29.1 42.2 63.5 96.6 34.9 184.4 53.8 125.1 47.8 57.1 27.1 51.4 39.7 11.1 38.2 43.3 143.6 21.1 27.0 161.0 42.7 60.4 144.8 90.1 29.0 70.7 58.7 78.2 24.0 74.5 42.0 61.7 30.3 337.1 40.1 48.6 74.9 26.0 17.5 45.3 62.5 27.9 76.1 35.7 88.6 84.7 24.5 86.1 65.2 0.1 5.9 1.8 7.4 6.6 8.9 5.8 7.0 7.0 8.7 5.3 7.1 8.6 0.3 6.3 8.9 8.9 7.6 5.8 27.5 25.2 24.0 30.6 23.4 23.9 24.0 24.4 25.9 23.9 30.6 21.9 2.5 0.0 4.4 7.8 13.4 8.0 8.6 3.8 7.4 5.3 41.9 31.9 6.8 8.6 3.1 7.3 4.2 119.1 12.5 6.7 1.9 9.8 15.1 3.9 7.4 6.2 5.4 12.6 7.2 8.2 111.7 6.0 5.6 6.9 0.0 18.1 7.1 67.7 21.8 11.8 9.0 9.2 4.1 9.1 6.0 32.0 7.2 6.6 0.0 29.0 47.9 2.5 6.2 6.6 5.0 7.0 4.3 13.9 10.0 14.1 11.7 3.9 2.9 3.1 13.1 5.5 5.2 35.1 21.5 7.6 6.3 227.9 8.6 9.4 15.2 7.8 ATRAID "APR3, C2orf28, HSPC013, p18" ENSG00000138085 "All-trans retinoic acid induced differentiation factor" Q6UW56 2 27212027-27217178 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051353 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051353: AB_2681451" "unprognostic (4.58e-2)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.85e-2)" "unprognostic (4.41e-2)" "unprognostic (1.59e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.73e-2)" "unprognostic (5.35e-3)" "unprognostic (2.36e-2)" "unprognostic (4.86e-2)" "unprognostic (1.77e-1)" "unprognostic (3.76e-1)" "unprognostic (1.92e-1)" 86.5 79.6 57.3 48.0 62.2 72.2 109.9 62.7 70.8 108.8 73.8 82.0 59.8 82.1 343.6 59.1 123.7 68.0 129.7 56.9 61.8 133.2 72.0 74.8 63.8 64.5 60.1 119.6 120.2 120.5 40.7 74.8 64.2 81.5 92.3 56.7 107.7 107.3 142.6 55.9 59.4 72.7 61.7 64.4 73.3 96.1 59.3 68.4 114.1 139.1 66.2 79.2 38.1 66.4 126.9 145.6 82.4 144.9 408.7 242.2 126.9 75.6 227.6 93.8 87.0 116.2 184.4 63.5 126.6 201.3 134.8 108.7 75.9 132.2 81.1 101.2 77.2 75.0 79.4 182.6 185.9 65.2 93.6 192.5 275.5 80.2 179.3 213.3 123.7 110.5 76.4 191.7 144.5 161.8 78.8 174.0 124.0 263.3 123.0 70.5 218.7 293.2 161.2 68.6 90.7 136.5 89.7 112.4 122.8 118.4 96.3 98.5 82.8 147.9 87.4 54.1 77.8 302.4 249.6 166.2 152.9 124.8 143.5 188.4 242.1 206.7 198.5 223.2 202.9 278.5 227.6 226.9 251.1 271.1 238.8 219.6 54.1 189.1 240.7 293.2 277.5 443.1 57.3 62.2 62.7 70.8 56.9 61.8 64.5 60.1 64.2 61.7 59.3 66.4 143.0 60.9 82.1 7.8 96.4 102.2 176.4 306.4 112.1 44.2 135.0 155.7 163.2 114.4 169.9 143.5 18.8 273.0 95.0 68.6 181.9 182.5 159.6 113.7 109.5 118.4 91.8 47.1 4.3 191.3 328.2 200.0 57.6 96.8 90.7 124.6 113.2 82.7 209.4 28.6 6.6 134.6 205.4 110.7 104.8 223.9 196.3 100.9 176.1 9.4 157.6 153.9 92.7 9.5 13.9 126.1 123.1 141.1 177.0 109.6 135.1 212.0 160.8 48.9 52.6 103.8 137.8 374.7 162.6 110.2 100.7 250.5 93.5 167.8 137.6 153.7 CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217369-27243943 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007781, HPA065158, HPA069341" Supported Supported Cytosol NA No 260000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "CAB007781: AB_562057, HPA065158: , HPA069341: AB_2686125" "unprognostic (1.69e-1)" "unprognostic (7.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.71e-3)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.72e-11)" "unprognostic (1.25e-1)" "unprognostic (2.22e-1)" "unprognostic (2.37e-1)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.93e-3)" 15.0 13.5 12.7 12.4 14.1 9.0 14.9 12.7 15.5 19.8 12.2 16.5 8.5 23.8 9.9 19.2 19.3 7.7 11.6 12.3 12.8 18.0 27.8 12.3 14.9 13.8 13.5 22.3 22.3 5.9 18.7 7.5 14.5 15.2 7.8 5.0 12.3 8.8 10.3 18.7 16.1 11.9 12.7 20.1 14.0 22.2 14.2 11.6 15.8 5.9 10.5 16.9 15.8 15.2 75.2 66.4 28.9 58.4 46.1 37.6 22.9 31.0 21.4 38.3 27.0 75.7 29.2 66.4 27.4 28.5 29.6 41.4 85.7 41.1 28.5 43.8 69.2 95.2 55.0 40.0 23.0 75.7 46.2 28.8 33.1 55.7 63.0 17.8 41.6 60.6 68.3 36.0 34.2 74.8 48.7 112.0 69.7 31.3 49.7 84.0 86.5 69.5 28.6 37.6 57.9 29.1 43.3 30.5 37.4 21.3 23.9 31.3 37.7 57.7 47.5 45.5 63.5 74.0 51.8 135.2 23.3 71.7 51.0 0.0 0.8 0.4 3.1 1.5 2.5 3.4 4.4 5.2 1.9 3.1 2.8 2.8 0.5 2.7 0.9 3.4 5.9 2.0 12.7 14.1 12.7 15.5 12.3 12.8 13.8 13.5 14.5 12.7 14.2 15.2 4.2 3.2 3.9 12.7 5.3 3.7 4.3 5.0 5.7 10.6 7.1 8.6 8.3 10.0 4.7 1.8 16.7 5.9 3.9 3.9 0.0 6.1 1.5 2.9 7.9 5.1 6.6 9.7 5.6 3.7 6.6 7.0 6.1 4.3 4.5 16.9 3.3 6.6 7.7 6.7 5.7 5.8 0.0 3.0 1.9 1.9 6.2 3.6 3.6 6.5 4.7 4.1 5.2 8.5 7.4 5.9 1.9 9.8 7.3 8.0 2.5 2.0 3.5 6.8 0.0 8.2 5.2 5.6 12.1 6.2 3.4 2.2 5.1 9.7 7.5 2.2 SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.4;Early spermatids: 17.8;Excitatory neurons: 15.6;Late spermatids: 42.4;Peritubular cells: 15.1;Spermatocytes: 16.6;Spermatogonia: 10.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HAP1: 11.2;Hep G2: 12.0;REH: 22.8;RH-30: 11.0" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" 0.1 2.1 14.5 0.1 10.3 0.3 0.1 0.0 18.2 0.2 0.0 0.1 0.0 0.4 68.5 0.1 0.3 0.1 7.9 22.2 0.0 0.1 0.2 0.2 0.5 0.5 0.0 0.2 0.0 0.5 0.3 0.0 0.8 0.3 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 35.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 1.5 0.4 1.3 0.1 2.0 0.2 0.2 0.3 0.0 0.0 1.3 1.4 0.5 0.5 0.0 0.1 0.0 8.8 0.3 11.2 0.0 0.3 0.0 1.2 5.9 0.5 12.0 0.2 0.2 2.3 0.0 0.0 0.6 0.0 0.2 0.9 2.9 1.7 0.1 0.2 3.9 0.1 0.4 1.8 0.4 0.0 22.8 11.0 1.4 0.0 0.3 0.0 0.7 2.8 0.0 0.0 0.1 0.0 0.8 0.1 0.3 5.1 0.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 14.5 10.3 0.0 18.2 22.2 0.0 0.5 0.0 0.8 0.0 0.0 1.5 0.3 0.0 0.0 2.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 17.8 0.0 0.1 0.4 0.0 0.0 15.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 42.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 15.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 16.6 10.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 DNAJC5G "CSP-gamma, FLJ40417" ENSG00000163793 "DnaJ heat shock protein family (Hsp40) member C5 gamma" Q8N7S2 2 27275433-27281499 "Predicted membrane proteins" Chaperone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 14 "epididymis: 46.9;testis: 22.8" "Group enriched" "Detected in some" 4 "Early spermatids: 69.1;Late spermatids: 83.6;Spermatocytes: 105.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA041445 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041445: AB_2677485" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (2.26e-1)" "unprognostic (3.99e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-1)" "unprognostic (4.06e-1)" "unprognostic (1.75e-4)" "unprognostic (2.08e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" "unprognostic (7.67e-2)" "unprognostic (1.97e-2)" 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.0 2.5 0.4 0.0 0.1 0.0 0.4 46.9 0.0 0.4 0.0 1.3 0.8 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.8 0.1 0.0 2.5 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.1 0.0 0.0 0.3 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 83.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 105.1 19.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 213.2;skeletal muscle: 580.7;tongue: 177.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 81.7;Ductal cells: 35.5;Exocrine glandular cells: 42.5;Pancreatic endocrine cells: 46.5;Skeletal myocytes: 17.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.1" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Group enriched" "Detected in some" 8 "HAP1: 7.3;NTERA-2: 15.6" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" 0.4 9.3 1.5 0.0 0.9 0.0 0.3 0.9 5.1 0.9 0.1 0.3 4.3 0.8 24.5 5.0 0.8 0.2 213.2 2.3 0.0 1.7 0.1 0.2 0.2 0.6 0.3 0.5 0.5 0.0 0.1 0.0 0.3 3.4 0.0 0.0 9.5 0.1 580.7 0.9 2.1 0.0 0.3 0.9 0.1 22.3 0.1 0.1 0.5 177.3 0.0 0.1 0.5 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.4 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 15.6 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 1.5 0.9 0.9 5.1 2.3 0.0 0.6 0.3 0.3 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.3 0.0 0.0 0.5 0.4 81.7 10.0 0.1 3.7 0.0 0.0 0.3 2.3 0.0 35.5 1.5 0.1 0.0 0.8 0.0 2.7 11.3 42.5 0.0 2.2 0.0 0.2 4.5 0.0 0.4 0.0 0.1 0.0 0.8 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.3 46.5 1.9 0.7 0.0 0.2 2.4 3.1 0.2 0.0 0.0 17.9 16.8 6.8 2.4 0.0 0.0 0.0 0.3 0.2 6.4 0.3 UCN "UI, UROC" ENSG00000163794 Urocortin P55089 2 27307400-27308445 "Predicted secreted proteins" Hearing Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2" "Cell type enhanced" "Detected in many" "Astrocytes: 7.8;Excitatory neurons: 6.5;Inhibitory neurons: 5.5;Oligodendrocytes: 6.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 19.4" "Low region specificity" "Detected in many" CAB010911 Approved Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 133000 "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "CAB010911: AB_261834" "unprognostic (7.35e-2)" "unprognostic (2.77e-1)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.42e-2)" "unprognostic (5.08e-2)" "unprognostic (7.72e-2)" "unprognostic (5.69e-3)" "unprognostic (2.66e-1)" "unprognostic (2.48e-1)" "unprognostic (1.15e-1)" "unprognostic (3.80e-2)" "unprognostic (3.75e-2)" "prognostic unfavorable (1.84e-7)" "unprognostic (4.84e-2)" "unprognostic (3.87e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" 1.5 5.1 8.6 0.6 8.2 1.1 1.5 8.4 13.5 3.3 4.2 2.4 0.3 2.4 0.5 0.9 3.0 0.8 4.2 8.0 7.3 2.0 5.9 1.9 0.7 9.7 18.2 2.9 2.3 0.0 4.3 1.0 14.9 3.0 0.0 0.9 0.9 0.3 4.8 1.3 1.9 0.4 7.1 2.9 1.3 2.8 8.4 0.6 1.7 0.4 0.2 2.8 1.7 10.1 1.2 2.7 0.4 0.7 1.2 1.0 5.1 0.4 1.0 0.4 0.4 0.2 2.1 1.1 0.6 0.4 1.2 0.4 0.4 0.3 0.0 3.4 4.4 2.4 2.0 2.2 2.9 0.2 2.6 1.5 2.0 0.2 2.4 2.6 0.0 2.0 2.4 1.9 0.1 2.0 1.3 7.2 4.4 0.1 2.8 3.5 2.3 1.5 0.1 0.5 0.7 2.3 1.1 0.1 6.4 0.3 1.1 3.2 0.2 0.8 4.8 1.4 1.9 19.4 2.3 0.7 3.7 5.7 1.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.1 0.0 8.6 8.2 8.4 13.5 8.0 7.3 9.7 18.2 14.9 7.1 8.4 10.1 0.8 0.0 0.5 7.8 1.1 0.5 0.3 0.3 0.0 2.3 1.8 1.0 0.4 4.3 0.2 0.0 0.0 0.6 3.2 0.5 0.0 0.7 0.6 0.5 0.9 0.8 0.0 2.7 6.5 3.8 0.6 0.7 0.0 0.5 0.0 1.2 1.1 1.1 0.7 1.7 5.5 0.3 2.0 1.3 2.4 0.4 1.5 0.9 0.0 3.7 0.9 1.8 0.0 2.5 6.0 0.6 1.1 0.7 0.1 0.7 1.1 0.5 0.5 3.5 0.0 1.5 1.2 1.1 0.6 0.0 0.0 0.8 0.8 0.4 0.5 0.1 MPV17 SYM1 ENSG00000115204 "Mitochondrial inner membrane protein MPV17" P39210 2 27309492-27325680 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (9.34e-3)" "unprognostic (2.70e-1)" "unprognostic (9.50e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-1)" "unprognostic (1.89e-2)" "prognostic unfavorable (6.99e-6)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.22e-1)" "unprognostic (1.48e-1)" "unprognostic (1.44e-3)" "unprognostic (2.59e-3)" "unprognostic (2.52e-1)" "unprognostic (5.10e-3)" "unprognostic (4.62e-2)" 50.2 86.5 56.4 37.8 58.1 31.3 39.9 59.1 58.4 36.0 59.3 32.5 25.0 37.9 47.7 32.6 37.7 36.7 78.2 56.3 59.1 48.6 22.6 39.1 43.2 58.8 57.1 43.7 33.2 70.0 38.9 35.0 58.1 34.1 34.1 26.7 35.9 35.0 18.3 32.0 27.5 57.7 56.9 37.1 29.1 15.5 60.3 46.0 51.6 30.0 48.1 44.9 28.1 63.2 74.1 68.2 49.7 42.6 202.7 237.0 46.6 70.8 143.6 67.2 60.7 55.0 52.0 41.5 72.8 97.2 124.0 61.3 64.1 134.1 69.5 56.9 63.7 79.5 58.8 105.6 125.4 47.3 48.7 229.3 116.3 118.6 169.4 94.3 100.2 49.8 77.0 77.1 113.9 107.4 46.9 71.5 55.7 106.7 69.1 64.6 73.2 85.2 149.2 58.5 33.1 107.2 37.6 43.7 82.1 49.3 49.0 60.6 88.6 67.0 68.8 83.4 76.4 108.1 106.1 130.4 109.2 105.4 76.1 59.5 93.7 42.9 59.3 81.4 64.4 84.5 60.5 67.4 120.5 73.6 58.0 67.8 7.8 76.0 81.7 87.4 81.4 92.1 56.4 58.1 59.1 58.4 56.3 59.1 58.8 57.1 58.1 56.9 60.3 63.2 36.0 25.6 29.3 10.7 26.3 17.2 32.8 69.2 33.0 20.5 49.5 52.8 48.9 18.6 46.5 33.1 8.4 51.1 26.3 8.8 64.6 43.3 27.4 17.3 32.6 35.9 16.8 21.6 18.4 24.3 60.2 37.5 12.2 17.5 42.5 28.7 28.2 9.9 116.9 8.4 22.7 15.0 59.0 28.5 24.0 34.2 35.4 33.7 40.9 8.4 38.1 38.9 28.8 13.6 15.5 20.7 12.9 35.0 31.4 32.1 17.6 87.1 36.7 12.7 0.0 30.1 30.8 15.5 21.2 33.9 18.8 59.4 22.2 41.8 17.7 30.7 GTF3C2 "KIAA0011, TFIIIC110" ENSG00000115207 "General transcription factor IIIC subunit 2" Q8WUA4 2 27325849-27357034 "Predicted intracellular proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA008274, HPA035836" Uncertain Supported Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA008274: , HPA035836: AB_10601813" "unprognostic (1.76e-1)" "unprognostic (9.64e-2)" "unprognostic (9.89e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (1.33e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (1.21e-8)" "unprognostic (1.57e-1)" "unprognostic (1.77e-2)" "unprognostic (1.47e-1)" "unprognostic (2.59e-2)" "unprognostic (7.39e-2)" "unprognostic (1.86e-2)" "unprognostic (1.01e-1)" "unprognostic (1.94e-1)" "unprognostic (7.97e-2)" "unprognostic (3.00e-1)" 18.7 25.6 19.5 23.2 20.8 23.5 21.1 26.2 27.6 19.0 23.5 25.3 22.4 19.8 23.7 34.5 24.4 15.3 23.2 19.9 20.8 23.3 21.1 19.7 26.6 21.2 18.7 20.7 30.7 33.1 20.0 19.6 20.0 20.1 27.7 25.2 25.2 18.5 28.7 32.2 24.2 23.3 17.2 26.8 24.3 26.0 22.0 30.4 29.4 18.5 33.5 23.2 21.4 28.1 86.2 75.7 62.5 60.6 36.2 35.2 91.2 30.8 41.8 39.8 33.7 56.3 53.7 75.1 54.1 43.0 40.8 50.6 93.2 59.2 38.0 59.5 81.0 63.3 48.5 76.0 33.0 69.7 60.6 44.4 52.3 45.4 58.4 38.0 51.8 50.4 90.1 54.9 38.8 70.4 64.9 50.7 118.2 69.0 47.6 79.1 69.2 83.9 56.8 63.9 58.0 101.5 33.1 78.6 57.7 52.8 42.2 39.3 39.6 48.2 52.4 36.9 58.1 60.2 71.9 169.4 48.1 55.4 53.8 29.6 18.2 14.5 14.3 15.0 15.1 13.3 12.6 15.2 15.6 11.4 12.4 12.2 8.4 13.3 19.2 9.8 8.5 19.7 19.5 20.8 26.2 27.6 19.9 20.8 21.2 18.7 20.0 17.2 22.0 28.1 7.9 19.2 22.1 11.8 17.5 9.8 9.8 11.9 18.2 11.3 13.9 11.6 11.7 14.3 14.9 5.5 22.9 19.3 12.9 22.2 9.8 16.6 54.9 13.6 10.9 10.3 3.5 24.8 17.3 22.8 23.6 10.0 17.3 14.6 18.3 16.2 10.0 11.1 16.1 10.1 16.2 17.6 12.2 18.4 7.6 61.9 9.3 12.1 5.4 16.9 18.3 8.9 12.3 14.1 18.9 21.5 9.0 7.9 18.6 13.0 16.0 11.8 14.8 18.0 6.6 9.7 11.8 9.1 16.4 19.4 12.6 20.0 13.7 11.8 15.1 14.4 EIF2B4 "DKFZP586J0119, EIF-2B, EIF2B, EIF2Bdelta" ENSG00000115211 "Eukaryotic translation initiation factor 2B subunit delta" Q9UI10 2 27364352-27370457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.4;Late spermatids: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032234, HPA039993, HPA068855" Approved Approved "Nuclear membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear membrane" "Actin filaments" "CAB032234: AB_668909, HPA039993: AB_2676790, HPA068855: " "unprognostic (2.26e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" "unprognostic (7.55e-2)" "unprognostic (2.37e-1)" "unprognostic (4.63e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.64e-2)" "unprognostic (2.18e-1)" "unprognostic (3.56e-3)" "unprognostic (1.11e-1)" "unprognostic (2.68e-1)" "prognostic unfavorable (5.46e-8)" "unprognostic (1.79e-1)" "unprognostic (1.70e-1)" "unprognostic (8.76e-2)" "unprognostic (1.67e-2)" 21.4 24.8 23.3 15.2 24.3 10.7 20.7 24.0 23.8 21.3 22.5 31.7 14.6 21.0 16.9 27.8 20.3 13.4 28.0 23.2 23.7 18.2 21.5 18.1 17.2 24.4 24.3 19.8 31.4 20.4 20.3 18.8 24.0 25.4 18.4 19.3 24.6 20.8 51.8 29.3 18.4 22.8 23.2 18.6 24.7 38.1 24.4 18.9 18.1 35.2 22.9 24.1 21.4 24.1 38.7 59.8 44.3 34.6 58.4 42.7 48.4 41.0 43.7 55.7 37.3 89.2 16.9 49.7 38.7 48.7 46.6 27.6 62.5 50.8 36.2 37.4 40.7 61.7 39.3 104.5 51.1 58.2 23.0 41.3 51.1 69.2 51.6 40.4 53.3 37.2 59.5 24.9 53.0 35.2 28.8 61.7 49.1 59.8 38.9 52.9 69.9 43.2 50.0 32.7 34.3 37.4 34.1 53.8 42.6 39.6 31.3 23.4 52.8 40.1 47.0 35.4 49.7 50.9 65.7 74.7 33.9 47.9 38.6 56.6 53.9 38.8 32.1 48.1 44.6 31.1 31.6 32.6 52.5 25.3 30.2 32.9 7.7 30.8 52.2 38.6 43.8 43.2 23.3 24.3 24.0 23.8 23.2 23.7 24.4 24.3 24.0 23.2 24.4 24.1 19.9 12.8 14.8 9.8 17.5 35.9 18.9 32.0 15.4 22.6 28.0 18.7 33.0 14.3 27.0 22.0 66.7 40.9 27.8 23.4 19.6 29.0 196.4 22.3 23.9 19.9 24.0 8.2 6.6 33.4 25.0 24.6 14.8 17.6 31.6 16.9 25.7 34.4 24.3 10.1 6.5 24.8 28.5 20.7 28.0 299.6 23.3 16.5 23.2 2.8 29.5 23.2 16.5 6.0 8.8 26.7 27.1 24.8 28.4 21.2 23.0 27.6 24.9 58.9 19.7 17.0 34.9 71.5 38.9 14.5 34.8 46.1 24.3 23.8 20.5 14.4 SNX17 KIAA0064 ENSG00000115234 "Sorting nexin 17" Q15036 2 27370496-27377535 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043867 Supported Enhanced Vesicles,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Cytosol "HPA043867: AB_10961129" "unprognostic (2.57e-1)" "unprognostic (7.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.61e-2)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (1.06e-3)" "unprognostic (1.86e-1)" "unprognostic (4.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.04e-2)" "unprognostic (9.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.20e-2)" "unprognostic (1.37e-1)" "unprognostic (2.39e-1)" "unprognostic (6.32e-3)" 62.5 74.6 32.2 23.1 32.6 19.8 57.0 35.3 31.8 59.7 32.1 58.5 17.3 62.8 16.6 62.2 57.7 22.1 60.3 30.3 32.7 54.6 62.9 53.8 32.3 33.5 33.1 62.4 53.9 42.5 61.1 28.1 37.1 54.2 23.3 12.8 50.3 31.6 49.2 57.0 53.3 33.4 36.3 80.8 54.1 34.1 35.0 43.9 54.3 33.9 33.8 59.8 50.9 37.0 40.1 70.0 45.3 56.4 85.9 71.5 29.0 47.3 85.2 71.8 52.2 43.5 37.8 39.5 55.4 113.9 61.9 23.7 42.4 63.8 57.9 40.7 72.5 44.8 20.3 55.4 80.9 47.6 41.6 66.9 56.7 49.6 59.5 54.1 78.3 32.7 35.5 32.8 87.2 47.7 50.2 31.3 29.2 62.5 67.1 22.7 74.0 64.9 53.5 34.1 46.3 55.1 38.6 39.0 18.1 31.9 30.5 29.6 50.6 57.4 31.6 33.8 45.5 56.8 47.5 49.4 50.0 49.8 60.9 87.5 138.7 88.9 65.6 135.2 66.9 72.7 61.2 67.6 135.6 73.2 57.5 60.6 30.8 72.2 146.9 73.8 78.5 231.9 32.2 32.6 35.3 31.8 30.3 32.7 33.5 33.1 37.1 36.3 35.0 37.0 60.8 16.0 39.1 6.5 68.3 32.5 48.2 78.3 32.5 30.9 47.1 61.3 31.5 35.8 43.3 29.5 14.6 173.5 69.3 56.9 82.2 84.0 8.9 34.4 39.9 52.7 55.1 49.2 6.8 63.9 132.7 60.3 35.2 25.6 43.1 64.5 47.5 64.9 134.9 45.4 7.7 48.3 79.3 118.1 42.7 9.7 58.4 83.4 69.4 2.8 141.9 80.1 76.2 11.1 11.2 64.8 54.1 85.0 60.3 41.4 75.4 95.3 38.6 23.2 32.9 41.4 68.4 58.0 53.2 55.0 34.4 99.6 63.2 102.1 60.0 34.9 ZNF513 "FLJ32203, RP58, Zfp513" ENSG00000163795 "Zinc finger protein 513" Q8N8E2 2 27377235-27380790 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Transcription regulation, Vision" DNA-binding "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SH-SY5Y: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051493 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "HPA051493: AB_2681505" "unprognostic (1.11e-1)" "unprognostic (1.68e-1)" "unprognostic (4.67e-3)" "unprognostic (1.16e-1)" "unprognostic (2.99e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (6.21e-5)" "unprognostic (2.86e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-1)" "unprognostic (9.48e-3)" "unprognostic (1.18e-1)" "unprognostic (5.18e-3)" "unprognostic (9.31e-2)" "unprognostic (1.79e-1)" "unprognostic (1.75e-1)" "unprognostic (1.01e-3)" 16.2 23.7 15.7 12.7 15.0 12.1 16.7 17.5 19.2 16.6 12.6 22.5 18.7 18.2 5.7 23.8 16.7 9.3 14.3 15.2 14.2 27.3 38.5 18.2 11.1 15.5 15.4 13.4 20.5 10.1 30.2 6.6 14.4 25.8 7.8 4.8 18.7 10.6 11.4 19.5 23.6 7.1 14.1 27.2 24.2 36.1 16.6 8.7 23.5 5.4 6.5 19.4 17.2 15.1 10.3 12.4 15.7 16.0 10.3 8.6 20.6 13.1 15.1 9.6 8.3 10.2 7.6 3.5 11.6 9.4 10.1 9.1 6.7 11.8 2.8 13.0 11.0 9.9 8.9 7.7 18.3 3.4 26.6 14.7 13.0 9.5 11.5 6.3 11.4 13.8 6.2 2.1 9.2 3.9 6.4 16.6 23.7 9.9 8.0 8.2 11.7 6.6 13.5 17.8 9.7 50.8 6.4 7.4 12.9 8.5 5.5 9.8 10.9 6.7 4.4 5.5 3.9 30.1 19.9 6.6 9.3 8.0 13.5 1.2 0.5 1.0 0.4 1.0 0.0 0.0 0.4 0.1 0.7 0.1 0.4 0.2 0.8 0.0 0.5 0.7 0.0 0.3 15.7 15.0 17.5 19.2 15.2 14.2 15.5 15.4 14.4 14.1 16.6 15.1 7.2 3.2 7.5 4.9 2.5 9.2 6.0 5.7 10.2 7.9 10.3 6.9 0.4 10.0 4.3 5.5 4.2 5.6 4.0 14.8 0.0 6.2 44.1 9.0 8.9 7.7 8.4 4.4 4.5 10.2 4.7 4.9 22.4 11.5 0.0 6.9 2.5 10.8 6.0 5.0 5.1 10.6 6.1 2.9 4.6 10.5 4.1 5.3 5.4 1.9 5.9 11.7 2.1 3.0 3.7 9.0 13.5 3.4 4.8 11.0 9.2 5.2 4.7 6.5 6.6 5.6 6.2 9.3 10.3 12.2 13.4 16.1 4.5 10.8 9.4 13.6 PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381195-27409591 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 233.9" "Cell type enhanced" "Detected in all" "Early spermatids: 1540.4;Late spermatids: 3492.8;Spermatocytes: 793.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm NA NA 19000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA035530: AB_10670021, HPA035531: AB_10610283" "unprognostic (7.50e-2)" "unprognostic (8.89e-2)" "unprognostic (1.53e-1)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (4.15e-2)" "prognostic unfavorable (3.14e-7)" "unprognostic (9.36e-3)" "unprognostic (7.73e-2)" "prognostic favorable (6.08e-5)" "unprognostic (3.74e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-3)" "unprognostic (1.06e-2)" "unprognostic (5.33e-2)" "unprognostic (1.78e-1)" "unprognostic (7.83e-2)" 46.0 49.6 34.7 45.1 35.1 73.5 43.6 35.4 37.8 38.4 36.9 48.3 39.9 45.6 26.1 62.6 39.0 28.0 44.9 35.0 37.0 40.7 45.3 40.6 59.6 35.4 36.0 34.9 53.0 41.4 43.4 37.6 35.3 36.0 51.3 20.0 45.1 38.8 95.7 41.2 43.0 44.9 35.1 47.1 47.8 233.9 36.0 64.9 36.8 53.0 75.3 47.0 39.6 35.3 302.0 243.1 174.0 134.8 108.7 88.0 160.6 182.8 119.8 214.8 170.9 377.7 154.4 352.7 130.9 130.9 181.8 160.3 296.4 205.6 191.4 148.4 241.1 343.6 172.9 404.0 97.9 343.5 139.2 95.7 116.9 219.2 175.1 101.7 209.1 171.1 293.3 106.0 165.5 269.4 256.7 370.5 254.1 207.1 173.1 261.1 365.0 185.3 145.9 206.4 233.2 264.0 164.4 178.9 135.9 137.4 99.4 111.3 169.5 159.3 192.6 141.6 281.8 229.0 277.0 545.5 124.8 275.6 122.5 67.3 41.5 59.0 57.5 52.3 56.8 44.7 61.1 60.3 65.4 37.9 45.1 47.4 20.9 55.0 71.4 91.9 88.9 48.0 34.7 35.1 35.4 37.8 35.0 37.0 35.4 36.0 35.3 35.1 36.0 35.3 72.9 64.1 51.3 9.8 76.7 81.1 88.7 71.9 83.6 40.8 63.1 59.3 37.9 52.9 63.7 69.9 29.2 93.9 114.2 81.0 33.2 135.7 1540.4 102.7 75.8 80.8 80.7 119.6 19.5 139.3 163.8 56.6 69.3 89.8 59.1 76.1 40.4 44.7 85.4 48.8 21.1 78.9 54.9 59.7 75.7 3492.8 70.2 68.2 24.9 17.8 127.3 69.7 112.3 17.1 15.9 156.7 52.7 71.1 137.8 152.1 52.6 61.4 61.8 41.7 46.0 54.9 80.5 793.3 298.9 108.7 80.6 53.1 89.7 123.7 106.4 122.6 NRBP1 "BCON3, MADM, MUDPNP, NRBP" ENSG00000115216 "Nuclear receptor binding protein 1" Q9UHY1 2 27427790-27442259 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 234.3;Extravillous trophoblasts: 231.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029527, CAB033078" Supported Supported Cytosol NA NA 39000 "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "CAB033078: AB_2154375, HPA029527: AB_10601379" "unprognostic (4.95e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (3.62e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (7.36e-2)" "unprognostic (1.44e-1)" "unprognostic (6.11e-2)" "unprognostic (3.13e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.84e-5)" "unprognostic (1.26e-1)" "unprognostic (2.69e-1)" "unprognostic (2.75e-2)" "unprognostic (3.48e-3)" 59.7 49.6 38.1 49.4 38.9 109.1 55.2 39.3 42.1 76.1 44.3 72.0 52.2 69.7 43.1 99.9 55.1 53.5 57.6 37.7 44.5 44.7 55.2 50.3 54.0 43.1 44.2 63.7 51.0 44.5 46.9 83.0 45.6 51.6 46.5 47.6 57.2 60.7 126.2 70.7 52.4 75.6 36.8 51.2 51.8 71.1 42.1 51.9 42.4 90.3 67.2 67.3 70.8 37.5 123.7 121.0 98.1 130.9 148.2 146.6 119.0 114.8 143.1 159.8 123.5 123.5 49.1 35.5 83.7 182.9 158.6 82.9 98.4 102.9 102.3 70.0 61.4 70.8 47.0 163.5 124.1 40.0 91.1 120.8 127.3 163.7 108.6 103.9 178.5 38.8 40.5 54.8 142.3 185.6 53.0 96.1 124.0 108.5 75.7 40.5 209.5 40.0 113.8 84.1 26.3 74.1 135.6 96.5 72.4 108.8 53.3 43.9 143.0 140.6 138.5 85.1 94.2 114.3 122.7 42.4 109.8 68.6 71.9 203.6 88.6 187.0 96.7 118.0 85.6 59.3 82.3 87.9 90.2 55.1 73.9 77.1 117.9 91.0 111.5 57.4 107.8 117.4 38.1 38.9 39.3 42.1 37.7 44.5 43.1 44.2 45.6 36.8 42.1 37.5 47.3 6.4 21.4 15.7 46.4 57.2 57.8 73.9 56.9 37.8 34.3 31.5 25.9 28.6 47.2 35.0 35.5 155.7 72.6 67.4 31.3 88.7 234.3 47.5 66.8 54.9 28.1 42.7 14.8 95.9 231.5 61.8 30.1 64.1 20.8 39.3 47.2 38.8 77.3 28.6 15.9 42.7 38.7 35.2 44.7 38.6 46.0 46.6 30.2 8.4 67.2 46.8 51.5 13.0 17.0 100.0 45.6 60.5 72.2 49.7 67.4 52.6 36.5 56.3 32.9 37.4 77.6 92.8 106.8 50.3 52.4 203.2 67.2 36.9 30.8 58.8 KRTCAP3 KCP3 ENSG00000157992 "Keratinocyte associated protein 3" Q53RY4 2 27442366-27446481 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 182.0;Proximal enterocytes: 168.7;Undifferentiated cells: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "MAIT T-cell: 6.8;memory B-cell: 4.5;memory CD4 T-cell: 5.6;memory CD8 T-cell: 2.6;naive B-cell: 6.4;naive CD4 T-cell: 6.6;naive CD8 T-cell: 2.7;T-reg: 4.4" "Group enriched" "Detected in many" 13 "B-cells: 6.4;T-cells: 6.8" "Cell line enhanced" "Detected in many" "A-431: 84.6;CAPAN-2: 122.5;OE19: 46.6;SCLC-21H: 60.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA047136, HPA060203" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA047136: AB_2679949, HPA060203: AB_2684221" "prognostic favorable (2.67e-5)" "unprognostic (5.93e-2)" "unprognostic (5.03e-2)" "unprognostic (3.41e-1)" "unprognostic (1.29e-1)" "unprognostic (7.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (9.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-2)" "unprognostic (4.63e-2)" "unprognostic (1.04e-1)" "unprognostic (3.73e-3)" "unprognostic (3.79e-2)" "unprognostic (8.21e-2)" "unprognostic (9.42e-3)" 2.2 2.7 3.0 6.3 3.5 3.0 16.0 5.3 5.6 11.8 3.7 39.6 44.3 5.8 1.8 18.3 24.9 9.5 0.7 2.9 3.5 7.9 9.8 11.3 3.3 3.9 3.5 2.4 44.6 18.6 14.1 2.9 3.7 20.9 27.8 7.3 38.5 12.7 3.2 14.1 45.5 1.7 3.0 3.1 42.4 2.2 3.3 3.7 11.5 0.0 5.2 10.0 11.2 4.6 84.6 1.2 6.1 2.7 0.3 0.6 17.4 0.9 0.3 1.0 0.9 32.7 122.5 1.0 1.1 0.2 0.5 28.4 0.9 25.0 0.3 1.0 0.6 2.2 1.9 2.7 0.0 0.3 3.9 1.1 2.7 0.6 1.5 1.2 1.0 2.8 1.8 1.5 0.9 27.2 0.9 7.8 27.7 46.6 1.1 0.8 1.8 2.5 1.7 2.4 60.2 2.2 2.3 25.4 3.6 2.0 2.5 1.4 2.4 3.4 5.4 1.2 1.1 7.0 5.9 1.1 2.3 1.1 0.8 0.0 0.0 0.0 0.6 0.0 6.8 4.5 5.6 2.6 0.0 6.4 6.6 2.7 0.0 0.5 0.0 0.0 4.4 1.5 3.0 3.5 5.3 5.6 2.9 3.5 3.9 3.5 3.7 3.0 3.3 4.6 1.1 22.4 27.9 2.6 2.9 23.3 125.1 135.4 71.7 4.9 100.9 105.2 0.5 88.6 92.5 42.3 8.4 17.0 1.9 74.2 5.9 105.4 6.4 50.9 3.8 2.7 62.0 3.6 1.2 182.0 27.6 3.4 68.3 47.9 4.5 0.9 1.4 15.2 2.1 1.7 1.1 123.6 105.8 1.0 2.5 4.7 0.3 2.0 7.2 1.9 2.9 1.9 2.1 1.5 1.3 108.7 112.9 0.0 0.7 123.7 168.7 7.7 85.2 5.9 0.0 0.9 6.9 3.8 29.4 48.0 15.5 7.9 3.0 0.7 190.2 144.2 IFT172 "BBS20, NPHP17, osm-1, SLB, wim" ENSG00000138002 "Intraflagellar transport 172" Q9UG01 2 27444377-27489805 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 439.9;Late spermatids: 703.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044893 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 34: Spermatids - Unknown function" "HPA044893: AB_10795009" "unprognostic (1.05e-3)" "unprognostic (6.52e-2)" "unprognostic (7.04e-2)" "unprognostic (3.57e-3)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.05e-6)" "unprognostic (6.86e-3)" "unprognostic (1.45e-1)" "unprognostic (8.49e-2)" "unprognostic (1.08e-1)" "unprognostic (1.51e-2)" "unprognostic (4.32e-2)" "unprognostic (9.52e-2)" "unprognostic (5.49e-2)" "unprognostic (1.19e-1)" "unprognostic (5.47e-2)" 3.1 3.3 2.2 2.5 2.6 1.8 4.0 2.5 2.4 5.2 11.8 4.6 1.8 4.5 1.6 2.4 17.0 3.2 4.3 2.3 2.8 4.5 1.5 4.9 2.0 3.6 3.6 8.9 4.8 13.0 9.9 2.4 3.5 3.6 2.1 5.7 4.2 4.2 3.6 2.9 2.7 3.8 2.4 3.9 3.5 12.5 2.4 2.7 5.9 3.9 2.1 3.6 3.4 3.7 5.8 5.3 7.1 10.0 12.6 10.6 4.5 5.5 4.0 6.5 5.5 4.8 4.6 6.3 8.3 7.3 3.9 6.4 13.4 6.7 6.2 3.1 9.4 16.1 9.4 5.6 7.3 7.8 3.4 8.6 3.0 10.3 3.8 9.0 10.8 7.3 5.3 2.2 2.4 4.5 4.4 3.8 5.0 4.6 5.5 0.0 3.7 3.5 5.0 3.7 5.5 8.8 2.8 4.8 9.7 6.0 4.8 4.6 11.6 2.9 1.7 3.7 8.3 2.8 1.7 6.7 11.9 2.3 5.7 0.0 0.4 0.3 0.4 0.6 0.3 0.7 0.2 0.4 0.9 0.5 0.3 0.3 0.0 0.9 0.1 0.4 0.2 0.4 2.2 2.6 2.5 2.4 2.3 2.8 3.6 3.6 3.5 2.4 2.4 3.7 5.2 3.2 9.4 53.5 3.1 2.0 16.6 35.3 8.6 15.4 17.2 12.1 6.3 38.6 32.7 23.9 52.1 1.0 1.7 82.4 0.0 34.4 439.9 59.0 7.1 4.5 34.7 7.6 63.2 98.7 0.6 5.9 23.9 14.2 0.0 11.0 5.7 1.2 1.7 5.0 64.3 96.4 57.0 3.2 1.6 703.6 12.8 2.8 5.4 11.2 1.9 7.1 5.2 24.6 44.9 104.9 106.3 10.9 2.4 7.5 142.0 2.3 154.6 41.7 0.0 11.7 8.5 22.6 6.6 10.1 1.4 0.4 2.8 10.1 75.1 39.8 FNDC4 "FLJ22362, FRCP1" ENSG00000115226 "Fibronectin type III domain containing 4" Q9H6D8 2 27491883-27495200 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 124.2;liver: 126.9" "Cell type enhanced" "Detected in many" "Early spermatids: 255.2;Hepatocytes: 130.9;Late spermatids: 557.6;Pancreatic endocrine cells: 89.2" "Cancer enhanced" "Detected in all" "glioma: 39.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 35.3;ASC diff: 34.7;HUVEC TERT2: 43.3;SH-SY5Y: 33.2;TIME: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051804, HPA063581" Uncertain Approved Nucleoplasm,Aggresome,Cytosol "Intracellular and membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Aggresome, Cytosol" "HPA051804: AB_2681617, HPA063581: AB_2685048" "unprognostic (2.57e-1)" "unprognostic (1.19e-3)" "unprognostic (3.87e-2)" "prognostic unfavorable (5.07e-4)" "unprognostic (1.46e-3)" "unprognostic (1.27e-1)" "unprognostic (4.77e-3)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (9.64e-2)" "unprognostic (8.28e-3)" "unprognostic (4.41e-2)" "unprognostic (1.28e-2)" "unprognostic (1.13e-2)" "unprognostic (5.74e-3)" "unprognostic (2.40e-3)" "prognostic unfavorable (6.11e-4)" 34.5 124.2 55.4 2.9 54.6 0.0 26.2 59.8 69.0 7.5 40.3 5.9 1.1 4.2 2.7 24.9 3.8 12.2 11.7 58.9 56.0 11.4 126.9 4.6 1.1 64.6 57.5 38.3 11.9 36.5 11.2 2.5 63.6 11.8 1.8 10.4 9.0 3.2 4.1 4.9 3.4 5.4 56.2 5.4 5.6 27.3 59.2 0.4 5.9 4.0 2.8 6.0 8.0 56.1 0.0 0.3 19.9 35.3 34.7 21.2 0.3 8.1 16.3 5.8 5.0 1.6 0.6 0.0 0.9 25.9 7.5 0.0 13.3 4.9 5.0 0.0 2.2 1.7 0.1 18.7 12.9 0.0 0.2 18.2 2.3 10.0 2.0 26.0 43.3 0.0 1.9 0.0 21.3 0.0 0.0 0.1 12.4 0.0 0.7 0.0 0.0 0.0 3.4 0.0 0.3 33.2 0.2 0.0 0.3 2.6 0.1 0.0 39.7 5.4 2.4 2.1 6.3 0.0 0.0 0.0 29.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 54.6 59.8 69.0 58.9 56.0 64.6 57.5 63.6 56.2 59.2 56.1 14.8 0.0 0.5 5.2 0.8 3.4 3.2 0.4 5.7 9.1 8.3 12.8 2.4 14.3 0.2 0.0 4.2 0.2 0.4 0.0 3.9 72.9 255.2 1.6 18.8 10.9 0.0 2.7 20.1 48.3 0.2 17.3 6.1 2.0 5.7 5.9 10.0 130.9 0.5 0.0 18.7 0.5 0.0 3.2 5.3 557.6 15.5 1.0 3.6 5.6 1.0 23.7 0.0 10.6 2.1 89.2 0.0 11.7 0.7 11.9 0.0 0.4 0.2 12.9 0.0 34.4 15.6 5.0 8.4 1.4 2.4 0.0 1.5 1.0 0.1 1.7 GCKR ENSG00000084734 "Glucokinase regulator" 2 27496839-27523684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 136.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 96.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 14.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.4;Hep G2: 20.7;HUVEC TERT2: 6.4;TIME: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034098, HPA045855, HPA052227" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Cytosol" Nucleoli "CAB034098: AB_2247323, HPA045855: , HPA052227: " "unprognostic (3.31e-1)" "unprognostic (2.11e-3)" "unprognostic (2.27e-1)" "unprognostic (6.97e-2)" "unprognostic (1.68e-2)" "unprognostic (5.70e-2)" "unprognostic (2.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.52e-1)" "unprognostic (4.12e-1)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (1.02e-7)" "unprognostic (6.51e-2)" "unprognostic (1.18e-1)" "unprognostic (9.27e-3)" "unprognostic (1.50e-2)" 0.8 7.1 0.8 0.2 1.3 0.9 0.6 4.7 1.6 0.5 1.4 0.1 0.7 0.5 0.6 1.5 0.2 2.3 0.4 1.0 1.3 0.5 136.4 0.2 0.6 1.7 1.2 5.8 1.8 0.2 0.4 0.2 1.6 0.5 0.3 0.9 0.4 0.2 0.3 0.8 0.2 0.3 0.3 1.6 6.5 2.7 1.1 0.2 0.1 0.1 0.3 0.3 0.4 1.4 0.2 0.4 0.4 0.2 0.3 0.2 0.1 0.0 0.1 0.3 0.0 0.4 0.1 0.2 0.5 0.7 0.2 0.2 0.2 0.0 0.0 0.1 0.0 13.4 0.7 20.7 0.8 0.0 0.4 0.3 1.0 0.5 0.1 2.2 6.4 0.1 0.0 0.2 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.5 0.2 4.2 0.1 0.3 0.6 0.2 0.4 0.1 0.2 1.2 0.1 0.2 0.8 0.2 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.4 0.1 0.1 0.4 0.3 0.0 0.1 0.0 0.2 0.8 1.3 4.7 1.6 1.0 1.3 1.7 1.2 1.6 0.3 1.1 1.4 0.3 0.0 0.0 1.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 7.9 0.1 0.6 0.6 0.0 0.0 2.0 10.4 0.0 0.2 18.3 0.1 0.0 0.1 0.7 96.5 0.1 0.0 1.6 0.0 0.0 2.1 0.0 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 13.7 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 1.7 0.2 0.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 C2orf16 DKFZp434G118 ENSG00000221843 "Chromosome 2 open reading frame 16" Q68DN1 2 27537386-27582721 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 21.4" "Cell type enriched" "Detected in some" 6 "Early spermatids: 94.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 2.4;SiHa: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052136, HPA056962" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 74: Testis - Spermatogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA052136: AB_2681742, HPA056962: AB_2683290" "unprognostic (4.32e-2)" "unprognostic (1.08e-2)" "unprognostic (8.36e-2)" "unprognostic (3.40e-3)" "unprognostic (6.36e-2)" "unprognostic (6.17e-2)" "unprognostic (6.15e-2)" "unprognostic (3.07e-1)" "unprognostic (9.35e-2)" "unprognostic (3.79e-3)" "unprognostic (4.59e-1)" "unprognostic (2.19e-2)" "unprognostic (8.82e-2)" "unprognostic (8.00e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-2)" "unprognostic (8.53e-3)" 0.1 0.4 0.1 0.2 0.1 0.0 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.2 0.0 0.3 0.2 0.2 0.3 0.1 0.2 0.2 1.2 0.1 0.1 0.3 0.1 0.5 0.3 0.0 0.5 0.0 0.3 0.2 0.0 1.5 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.4 21.4 0.3 0.0 0.4 0.0 0.0 0.2 0.2 0.2 0.6 0.6 0.9 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.8 0.3 0.8 0.0 0.6 0.2 0.0 0.0 0.0 0.6 0.1 1.2 0.5 0.6 0.0 0.7 0.5 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.5 0.8 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.5 0.5 0.2 0.0 0.6 2.4 0.4 1.8 0.4 0.2 0.1 0.4 0.4 1.1 0.5 0.8 0.3 0.4 0.1 0.0 0.7 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.2 0.3 0.1 0.3 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.4 94.1 0.3 0.2 0.1 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 0.0 0.0 0.0 14.4 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF512 KIAA1805 ENSG00000243943 "Zinc finger protein 512" Q96ME7 2 27582969-27623217 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031430 Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA031430: AB_10603844" "prognostic favorable (9.79e-4)" "unprognostic (4.19e-2)" "unprognostic (1.87e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.33e-1)" "unprognostic (3.07e-2)" "unprognostic (7.75e-3)" "prognostic favorable (5.08e-9)" "unprognostic (6.08e-2)" "unprognostic (2.33e-1)" "prognostic favorable (5.19e-4)" "unprognostic (1.10e-2)" "unprognostic (8.09e-3)" "unprognostic (4.44e-2)" "unprognostic (1.85e-1)" "unprognostic (5.66e-2)" "unprognostic (5.60e-3)" 11.3 13.1 8.8 10.7 9.4 6.1 16.6 9.1 12.6 19.5 8.1 16.5 7.8 25.0 14.9 8.3 21.4 10.9 13.1 9.1 12.5 12.4 7.0 13.8 16.9 8.6 10.3 34.3 7.7 20.1 13.6 13.0 9.1 18.1 12.0 26.4 11.1 19.2 7.4 7.2 12.9 16.9 8.7 17.0 11.0 13.2 11.5 27.0 20.5 10.5 17.5 16.4 13.0 11.1 26.2 22.8 46.2 20.6 22.4 25.2 0.0 12.7 17.9 23.6 27.7 17.7 16.2 22.8 14.0 14.6 19.6 8.7 41.3 12.0 25.0 21.2 33.0 47.9 18.4 27.0 17.3 31.4 20.8 23.2 12.9 18.4 5.3 18.9 37.9 39.3 42.0 16.2 35.0 3.3 3.3 24.0 32.1 17.2 0.0 52.2 65.0 19.8 16.8 7.2 45.0 44.8 12.0 7.6 36.0 21.9 9.3 17.8 31.5 8.3 20.0 8.6 16.8 16.2 12.1 38.9 12.5 38.4 17.3 24.5 5.5 9.8 10.2 6.7 14.1 12.4 12.9 15.0 8.2 11.1 17.1 14.6 1.7 22.1 5.5 5.9 9.8 10.8 8.8 9.4 9.1 12.6 9.1 12.5 8.6 10.3 9.1 8.7 11.5 11.1 8.9 9.6 14.2 16.6 10.0 3.8 10.4 4.3 6.8 22.8 8.1 7.6 15.6 7.2 7.8 18.4 16.7 1.6 9.7 2.2 9.8 6.8 11.9 5.2 12.7 11.5 9.0 14.7 22.5 1.9 1.1 11.6 8.2 5.2 6.3 25.5 11.7 4.4 5.3 18.5 28.9 6.3 6.1 7.2 7.1 5.7 14.9 6.2 1.8 23.4 8.9 17.0 9.2 25.1 27.2 4.6 3.3 17.3 9.0 5.8 2.3 4.2 8.9 15.7 19.7 14.6 13.4 8.3 9.0 6.6 3.0 1.2 10.3 13.6 5.0 6.9 CCDC121 "FLJ13646, FLJ43364" ENSG00000176714 "Coiled-coil domain containing 121" Q6ZUS5 2 27625638-27629012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.3" "Cell type enriched" "Detected in many" 4 "Early spermatids: 186.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 10.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA051791 Uncertain Approved "Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Actin filaments, Cytosol" "HPA051791: AB_2681611" "unprognostic (1.52e-1)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (3.93e-1)" "unprognostic (1.28e-1)" "unprognostic (4.71e-3)" "prognostic favorable (4.12e-4)" "unprognostic (4.03e-2)" "unprognostic (1.23e-1)" "unprognostic (5.65e-4)" "unprognostic (7.78e-2)" "prognostic favorable (1.87e-5)" "unprognostic (2.50e-1)" "unprognostic (1.72e-1)" "unprognostic (7.86e-2)" "unprognostic (5.42e-2)" 4.0 3.1 5.1 1.8 5.7 1.3 5.2 6.1 6.3 3.9 5.0 3.0 2.4 4.8 4.4 2.8 7.1 2.6 6.0 4.8 5.6 5.3 2.9 4.0 2.3 8.6 7.2 9.9 2.4 7.7 2.5 3.4 6.0 4.3 3.0 7.2 5.3 5.7 3.6 3.0 2.2 3.4 5.4 4.1 3.4 25.3 8.6 2.4 7.1 5.6 2.2 2.3 1.8 7.8 3.3 3.8 5.1 5.7 9.1 4.0 6.4 1.7 0.8 1.7 0.8 2.9 3.0 1.7 2.6 1.1 4.9 3.1 3.8 1.4 1.8 2.4 4.1 1.0 2.1 3.8 1.7 1.5 2.9 1.3 4.5 0.9 2.4 2.8 3.4 0.8 4.6 2.3 2.4 2.8 1.2 1.6 5.3 4.2 1.9 5.7 12.4 3.0 3.5 2.6 6.6 7.6 1.4 6.3 2.2 4.1 5.2 3.6 1.8 1.5 5.5 1.3 4.7 1.4 1.5 2.5 3.6 2.1 1.8 1.8 1.9 10.8 0.4 2.9 1.3 2.3 1.4 0.5 1.4 1.9 2.3 1.6 4.2 2.3 3.4 0.4 0.3 1.0 5.1 5.7 6.1 6.3 4.8 5.6 8.6 7.2 6.0 5.4 8.6 7.8 7.3 6.4 2.6 1.6 2.9 0.6 1.7 0.8 0.6 5.1 2.4 3.2 3.2 4.3 1.9 0.0 20.9 3.1 1.3 1.9 7.9 3.6 186.5 17.1 5.2 5.8 1.2 1.7 0.7 1.1 2.0 4.2 2.6 7.6 0.0 2.8 5.3 2.0 1.9 3.3 1.1 1.3 2.0 1.6 2.1 44.7 8.7 2.2 1.8 0.0 0.8 12.7 0.0 1.5 2.9 2.0 0.8 6.8 0.3 1.2 1.4 3.9 21.2 12.4 13.1 5.6 3.2 31.0 10.0 1.4 1.1 1.8 1.7 4.9 2.1 0.8 GPN1 "ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1" ENSG00000198522 "GPN-loop GTPase 1" Q9HCN4 2 27628247-27651511 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 86.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036793, HPA036794, CAB037303" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" Mitochondria "CAB037303: AB_477173, HPA036793: AB_2675318, HPA036794: AB_10672230" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (5.64e-2)" "prognostic unfavorable (2.88e-5)" "unprognostic (2.57e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.71e-5)" "unprognostic (3.50e-2)" "unprognostic (8.27e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-3)" "unprognostic (2.34e-1)" "unprognostic (1.21e-2)" "unprognostic (2.51e-1)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.72e-1)" 22.8 22.8 19.3 20.3 19.8 34.1 26.4 19.9 26.1 18.1 19.5 22.7 19.9 19.1 19.9 25.5 21.0 18.6 21.3 19.4 21.6 26.3 24.6 18.6 28.7 22.5 22.6 18.4 22.8 25.9 16.6 26.5 21.8 17.7 25.6 24.9 21.5 16.9 32.4 24.8 19.6 22.4 19.6 22.2 20.6 25.5 21.9 30.1 22.8 27.2 30.3 24.0 19.5 21.2 94.6 53.3 48.8 35.4 44.3 44.8 48.7 52.0 50.5 70.7 52.1 58.0 47.4 58.8 49.2 56.4 65.4 39.5 67.6 63.4 71.5 55.4 47.6 66.8 38.3 70.7 57.3 100.0 33.7 46.7 54.8 72.6 67.1 49.4 75.2 51.5 84.7 53.5 84.1 54.2 60.3 75.1 83.4 70.9 50.7 60.2 144.4 61.0 57.9 53.5 42.9 67.6 57.2 61.5 58.4 44.7 37.1 56.0 62.9 61.5 91.1 30.9 122.7 60.8 71.8 156.9 88.0 85.0 51.8 92.4 61.3 55.1 79.1 71.6 86.0 74.6 72.2 92.0 89.7 68.7 63.8 78.2 9.3 106.1 72.1 46.8 79.2 82.3 19.3 19.8 19.9 26.1 19.4 21.6 22.5 22.6 21.8 19.6 21.9 21.2 17.6 12.8 10.4 2.3 18.7 21.7 21.7 28.2 10.8 9.2 14.8 11.8 11.8 14.3 19.7 14.7 4.2 43.5 28.8 9.5 23.5 46.4 86.3 20.5 14.1 17.3 17.4 18.7 6.6 36.3 46.2 14.3 9.7 21.7 24.7 17.7 17.5 10.2 33.4 11.8 6.6 13.0 20.3 20.1 26.8 76.0 14.9 17.6 23.2 2.8 28.9 15.0 27.8 5.0 5.0 46.3 13.5 10.9 11.2 20.1 16.2 20.8 14.3 10.9 13.1 13.2 19.0 36.6 23.4 13.6 18.6 33.1 31.0 20.2 20.0 18.9 SUPT7L "KIAA0764, SPT7L, STAF65, STAF65gamma" ENSG00000119760 "SPT7 like, STAGA complex subunit gamma" O94864 2 27650809-27663840 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039565, HPA063643" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA039565: AB_10795109, HPA063643: AB_2685070" "unprognostic (1.10e-1)" "unprognostic (1.15e-1)" "unprognostic (3.07e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (7.54e-2)" "unprognostic (3.70e-1)" "prognostic unfavorable (4.46e-7)" "unprognostic (5.15e-2)" "unprognostic (1.43e-3)" "unprognostic (2.27e-2)" "unprognostic (1.97e-3)" "unprognostic (9.75e-3)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.26e-1)" "unprognostic (4.86e-1)" "unprognostic (3.79e-1)" "unprognostic (5.23e-3)" 31.2 35.1 31.9 22.5 32.0 35.7 27.7 32.0 37.5 34.3 38.9 30.9 22.9 31.9 25.0 25.8 32.2 20.4 36.8 31.9 33.3 33.4 37.8 29.6 27.4 31.1 31.9 39.6 31.1 22.8 46.2 27.1 32.0 34.0 25.3 55.5 24.0 22.1 30.2 20.8 32.7 28.1 30.3 41.6 29.8 20.6 31.9 26.2 36.3 27.1 24.2 29.2 29.5 35.4 33.6 28.6 41.2 31.9 36.8 30.1 49.0 32.0 30.9 28.4 30.4 37.2 36.8 29.2 32.9 34.0 40.0 35.8 37.3 35.6 27.6 33.7 36.1 39.8 43.7 42.4 48.1 32.4 37.5 42.3 43.8 42.0 44.0 52.7 37.3 35.3 45.8 34.0 37.3 23.1 28.1 52.9 27.5 33.5 25.0 26.8 44.1 37.4 36.7 31.1 32.5 42.3 28.6 29.6 54.7 52.0 20.5 27.9 28.8 39.2 29.0 19.9 30.8 60.9 47.8 60.4 30.5 39.8 27.3 30.4 14.8 13.6 18.2 15.7 20.7 10.6 14.3 19.0 20.9 17.3 17.2 16.3 3.7 22.9 14.7 14.0 17.6 13.6 31.9 32.0 32.0 37.5 31.9 33.3 31.1 31.9 32.0 30.3 31.9 35.4 15.3 22.4 17.1 33.6 15.9 8.4 13.2 19.9 13.1 18.6 12.7 11.7 21.3 12.8 21.6 22.0 41.7 34.2 25.8 12.1 21.5 18.1 12.5 19.1 18.3 18.5 10.8 11.1 31.2 14.6 29.3 17.7 21.4 14.7 19.6 20.7 15.7 15.6 25.1 15.2 32.7 12.3 12.2 12.3 11.1 3.9 13.7 17.1 3.6 14.0 13.4 19.0 16.5 17.6 33.1 13.9 8.2 15.4 25.5 8.5 10.8 20.6 24.3 24.7 19.7 15.0 16.5 29.4 22.6 15.4 8.7 42.3 19.3 22.1 13.9 11.6 SLC4A1AP "HLC3, kanadaptin" ENSG00000163798 "Solute carrier family 4 member 1 adaptor protein" Q9BWU0 2 27663471-27694976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036679 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA036679: AB_2675244" "unprognostic (5.63e-2)" "unprognostic (1.01e-1)" "unprognostic (4.62e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.21e-1)" "unprognostic (7.89e-3)" "prognostic unfavorable (3.76e-7)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (9.66e-2)" "unprognostic (9.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.79e-4)" 13.7 16.6 15.3 16.1 16.2 15.8 14.5 17.9 20.9 11.8 12.7 12.3 12.6 13.4 12.4 15.1 12.7 10.4 20.6 16.4 16.2 16.0 16.2 13.9 17.4 15.7 15.6 15.5 14.4 21.1 12.7 15.7 15.7 12.9 12.9 19.8 12.9 12.0 30.6 16.4 13.3 13.2 13.3 15.0 13.9 33.9 15.6 17.1 15.3 22.1 16.9 12.6 12.0 16.4 44.6 25.4 25.1 23.6 25.3 23.2 36.8 36.1 24.8 37.2 30.3 37.4 31.7 28.0 32.7 29.1 39.2 31.0 40.6 28.0 33.2 39.2 33.2 32.2 26.2 41.5 30.7 46.6 29.5 20.9 34.8 37.1 34.8 31.2 38.4 27.1 47.5 29.7 34.7 27.1 31.5 45.4 25.4 29.3 24.7 25.9 54.9 32.4 38.5 20.4 27.2 26.8 28.1 37.9 36.0 25.2 23.0 30.1 39.3 34.5 31.3 24.2 42.7 48.5 73.8 88.4 37.4 36.8 28.2 104.8 33.4 48.9 31.6 32.6 31.8 26.1 28.6 28.0 25.8 36.7 34.5 29.1 31.9 43.7 37.6 20.8 34.9 28.0 15.3 16.2 17.9 20.9 16.4 16.2 15.7 15.6 15.7 13.3 15.6 16.4 17.1 32.1 28.9 14.7 17.3 11.9 12.3 27.1 14.8 19.9 13.3 11.0 30.1 11.5 29.1 18.4 18.8 24.5 21.0 11.4 5.9 28.4 47.2 22.0 20.3 21.9 16.3 11.8 25.5 36.9 20.3 17.4 13.3 20.4 38.6 18.5 15.4 13.9 24.4 25.2 23.7 11.5 16.2 13.9 8.2 7.9 17.4 18.9 17.8 8.4 31.5 21.6 19.6 12.5 18.2 30.5 9.3 19.2 22.1 8.7 11.5 16.1 24.4 21.1 32.9 23.3 21.7 143.4 82.4 15.7 11.9 24.4 21.8 21.5 10.1 10.8 MRPL33 "C2orf1, RPL33L" ENSG00000243147 "Mitochondrial ribosomal protein L33" O75394 2 27771717-27988087 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1318.9;Distal tubular cells: 710.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066872 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA066872: AB_2685739" "unprognostic (5.13e-2)" "unprognostic (1.06e-1)" "unprognostic (1.64e-2)" "unprognostic (7.92e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.68e-4)" "prognostic unfavorable (1.66e-4)" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.78e-2)" "unprognostic (9.67e-2)" "unprognostic (2.48e-1)" "unprognostic (1.70e-3)" "unprognostic (1.54e-1)" "unprognostic (8.20e-2)" 157.7 642.9 142.0 66.7 146.7 98.2 131.4 145.2 215.2 127.7 146.4 233.3 76.8 145.7 151.2 94.1 140.8 81.8 555.1 142.2 146.0 297.4 135.6 131.6 79.8 143.2 141.5 132.5 120.0 161.0 189.2 74.2 142.9 151.1 98.0 135.8 114.8 120.7 716.4 79.0 114.8 121.2 142.6 122.9 166.7 108.6 143.0 110.5 112.8 650.0 81.9 162.7 110.1 148.5 378.2 168.6 302.0 124.0 186.5 209.7 141.3 233.7 294.8 230.7 300.9 151.0 288.2 108.1 286.5 246.9 347.4 112.8 171.6 186.1 328.9 169.6 325.9 211.0 161.8 272.2 282.7 213.4 120.5 270.6 162.2 209.1 364.8 370.9 297.2 163.5 167.6 178.4 307.1 126.0 147.6 231.8 170.4 384.0 241.9 73.8 341.1 152.1 711.5 150.6 172.8 248.4 161.7 205.2 268.1 277.6 92.0 216.5 253.1 145.8 314.7 143.3 375.0 205.5 347.2 325.7 200.8 346.6 137.1 502.5 203.4 211.2 126.7 160.5 136.8 128.3 143.8 135.6 284.0 112.3 121.5 147.2 154.2 125.9 160.6 183.3 175.0 125.4 142.0 146.7 145.2 215.2 142.2 146.0 143.2 141.5 142.9 142.6 143.0 148.5 213.3 179.5 144.5 10.4 104.3 56.0 107.2 283.5 66.0 48.6 171.2 190.4 1318.9 165.8 205.6 321.8 25.0 138.1 103.8 132.3 710.2 202.8 97.0 249.6 143.3 207.1 153.2 66.3 16.3 349.6 131.4 131.1 81.1 229.1 190.4 91.7 165.0 259.2 150.2 42.1 17.2 186.8 207.5 161.3 120.2 53.2 170.6 119.3 154.7 6.5 200.7 134.4 141.1 12.1 16.8 239.3 151.3 197.8 84.7 134.7 134.9 386.1 191.5 64.9 164.3 134.3 184.0 214.9 152.4 71.4 57.1 104.0 113.0 101.8 173.9 129.9 RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781379-27890681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 79.0;Proximal tubular cells: 110.9;Respiratory ciliated cells: 59.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 17.8;RPTEC TERT1: 40.8;U-266/84: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019725, HPA028285" Enhanced Approved Nucleoplasm,Cytosol No No 11000 "Cluster 22: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "HPA019725: AB_1856105, HPA028285: AB_10601480" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-2)" "unprognostic (5.54e-3)" "unprognostic (4.15e-3)" "unprognostic (2.44e-1)" "unprognostic (1.43e-2)" "unprognostic (4.77e-2)" "unprognostic (2.45e-1)" "unprognostic (5.35e-2)" "unprognostic (1.46e-1)" "unprognostic (3.98e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (9.27e-2)" 5.8 24.8 3.9 2.0 4.3 1.8 3.9 5.2 5.1 3.5 5.0 6.1 25.2 2.8 10.9 3.1 15.5 2.7 5.2 4.1 4.4 27.5 46.5 3.1 1.7 4.4 4.6 8.1 4.6 9.3 11.0 1.8 4.3 2.4 5.2 13.8 2.1 3.4 8.2 1.5 25.6 2.2 3.9 1.7 2.8 9.2 3.9 3.1 9.8 5.9 2.2 2.2 2.3 4.4 6.4 4.9 0.5 0.6 0.4 1.7 3.9 1.3 1.7 1.5 1.1 9.3 2.9 2.4 17.8 3.6 3.0 2.3 0.6 2.7 2.1 0.9 0.3 0.1 0.7 8.2 2.7 1.7 0.2 2.4 3.3 5.8 7.8 1.5 1.2 3.8 0.5 4.0 3.6 8.2 1.5 4.6 0.8 4.6 4.3 1.8 0.3 1.4 40.8 0.5 1.7 2.5 6.1 7.7 2.8 2.3 3.9 9.3 0.2 1.2 0.9 4.3 2.7 13.6 18.2 3.8 3.6 5.6 0.2 1.6 2.5 1.4 1.9 0.9 4.2 4.4 2.7 4.8 3.5 3.7 3.1 2.3 1.0 4.5 0.2 0.4 4.2 2.3 3.9 4.3 5.2 5.1 4.1 4.4 4.4 4.6 4.3 3.9 3.9 4.4 9.9 6.4 5.0 14.7 24.0 2.0 3.1 11.7 26.7 10.7 5.1 7.1 7.1 5.7 9.7 18.4 4.2 4.2 10.5 12.2 46.9 12.6 36.9 35.2 2.4 7.8 3.6 3.0 13.9 12.3 1.3 10.9 8.6 7.4 2.5 4.6 2.9 29.5 6.5 8.4 18.3 4.7 6.1 4.4 3.4 26.4 1.5 50.8 1.8 2.8 2.4 15.5 3.1 15.6 10.3 7.0 14.9 2.6 21.2 1.0 79.0 110.9 59.0 25.6 0.0 3.3 11.2 23.8 20.0 5.2 1.6 1.5 19.6 9.5 10.7 1.9 BABAM2 "BRCC4, BRCC45, BRE" ENSG00000158019 "BRISC and BRCA1 A complex member 2" Q9NXR7 2 27889941-28338901 "Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "adrenal gland: 380.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.1;Distal tubular cells: 84.1;Ductal cells: 53.4;Proximal tubular cells: 84.1;Syncytiotrophoblasts: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017926, HPA048867" Enhanced Supported Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017926: AB_1845443, HPA048867: " "unprognostic (1.28e-1)" "unprognostic (2.30e-1)" "unprognostic (1.53e-3)" "unprognostic (1.61e-3)" "unprognostic (1.89e-1)" "unprognostic (2.68e-3)" "prognostic unfavorable (6.33e-4)" "unprognostic (1.03e-1)" "unprognostic (2.38e-2)" "unprognostic (8.98e-2)" "unprognostic (2.13e-1)" "unprognostic (6.52e-2)" "unprognostic (4.41e-3)" "unprognostic (1.02e-1)" "unprognostic (4.74e-2)" "unprognostic (2.91e-2)" "unprognostic (1.22e-2)" 30.9 380.0 22.1 21.2 25.2 41.6 27.5 22.9 28.4 31.8 24.6 27.2 18.3 32.1 33.5 24.5 31.0 32.0 54.2 27.4 28.4 54.2 28.6 24.9 20.5 22.4 23.4 36.3 21.7 35.1 32.8 23.3 30.9 24.9 26.2 26.2 20.5 29.0 73.8 25.9 23.0 36.9 18.6 28.6 25.2 27.2 21.1 21.4 24.0 54.8 26.3 31.2 25.3 21.6 39.5 42.8 33.6 35.7 42.4 56.5 33.2 19.4 49.0 36.0 37.2 36.5 39.4 44.4 64.1 47.3 28.9 25.7 27.7 50.9 52.5 37.8 37.1 53.2 17.5 40.9 61.3 28.1 41.5 139.0 43.6 50.3 51.9 45.1 38.7 41.0 27.7 47.3 50.7 33.3 32.8 34.2 25.7 51.4 27.8 29.9 53.6 42.9 104.2 20.4 22.0 35.0 23.0 39.9 40.3 33.9 28.6 36.5 31.7 34.1 45.2 31.7 27.1 53.5 55.8 57.7 63.5 75.6 36.4 106.3 65.6 27.8 57.9 53.1 64.6 50.6 48.7 55.3 86.3 37.6 45.7 43.6 34.3 59.0 55.3 34.4 62.2 56.9 22.1 25.2 22.9 28.4 27.4 28.4 22.4 23.4 30.9 18.6 21.1 21.6 26.7 3.2 19.6 0.0 7.0 0.0 0.0 0.0 0.0 0.0 16.0 18.0 0.0 0.0 5.6 40.5 0.0 46.1 19.0 0.0 84.1 53.4 0.0 22.6 17.4 10.0 0.0 0.0 0.0 44.3 36.8 11.0 0.0 32.5 31.5 23.1 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 25.8 0.0 0.0 0.0 0.0 20.2 0.0 0.0 4.0 0.0 0.0 84.1 8.7 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 48.2 9.7 44.5 0.0 0.0 FOSL2 "FLJ23306, FRA2" ENSG00000075426 "FOS like 2, AP-1 transcription factor subunit" P15408 2 28392448-28417317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 287.6;Langerhans cells: 319.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 36.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004817, CAB013460, HPA061417" Supported Enhanced Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB013460: , HPA004817: AB_1849014, HPA061417: AB_2684509" "unprognostic (1.21e-1)" "unprognostic (3.60e-1)" "unprognostic (1.21e-1)" "unprognostic (8.55e-2)" "unprognostic (1.28e-3)" "unprognostic (3.41e-2)" "unprognostic (7.24e-2)" "unprognostic (3.78e-3)" "unprognostic (1.08e-1)" "unprognostic (7.73e-3)" "unprognostic (1.40e-2)" "unprognostic (2.08e-1)" "unprognostic (2.38e-1)" "unprognostic (2.38e-1)" "unprognostic (1.72e-2)" "unprognostic (1.99e-2)" "unprognostic (2.79e-2)" 149.4 169.7 18.8 67.6 18.4 232.1 78.6 18.8 31.8 83.0 17.4 64.3 30.2 77.8 7.0 129.5 85.7 79.6 75.1 34.7 32.2 65.8 30.9 83.4 9.1 36.0 19.3 133.5 37.2 7.5 46.6 46.9 18.8 53.8 40.2 10.7 47.4 26.7 101.7 103.4 52.2 81.5 18.2 32.7 76.6 7.3 23.5 17.2 35.2 33.9 16.6 82.3 112.1 15.0 45.0 30.2 2.0 23.2 23.9 41.6 62.0 37.7 38.0 58.8 51.1 35.9 34.6 0.2 53.9 48.6 59.6 42.0 2.5 49.7 52.6 10.6 3.1 4.6 59.3 6.3 37.3 7.9 18.9 66.9 123.3 69.0 60.5 49.5 31.2 1.5 0.6 12.5 39.7 7.3 0.7 24.3 3.6 45.2 14.8 1.8 57.4 4.3 94.3 152.5 15.7 2.3 61.0 35.2 10.9 16.8 3.8 35.5 93.8 122.8 81.9 72.3 55.2 19.1 7.6 0.2 81.5 43.3 21.6 17.2 9.9 8.7 7.7 7.3 7.4 0.0 1.6 3.8 3.9 0.0 0.4 2.5 36.6 4.6 6.4 1.3 1.2 5.1 18.8 18.4 18.8 31.8 34.7 32.2 36.0 19.3 18.8 18.2 23.5 15.0 183.1 32.1 50.9 4.6 20.2 143.1 86.3 85.8 90.0 0.8 76.4 41.7 27.9 70.1 59.7 167.3 0.0 27.4 287.6 140.6 19.6 58.5 1.3 115.7 88.0 111.0 28.1 4.4 11.9 59.8 148.3 79.7 115.7 193.6 108.3 68.1 56.7 16.5 37.4 0.0 8.1 65.2 40.7 58.0 319.8 4.3 22.4 181.2 85.4 15.0 62.8 2.3 53.5 0.5 0.6 54.1 91.5 24.5 67.0 82.2 124.8 35.1 38.2 1.4 26.3 93.8 122.3 1.6 2.5 157.6 150.7 50.2 142.4 23.6 57.6 152.8 PLB1 "FLJ30866, PLB" ENSG00000163803 "Phospholipase B1" Q6P1J6 2 28457145-28644142 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 39.0" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 112.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 3.0;eosinophil: 3.0;intermediate monocyte: 4.4;myeloid DC: 5.7;neutrophil: 8.8;non-classical monocyte: 5.0" "Group enriched" "Detected in many" 40 "dendritic cells: 5.7;granulocytes: 8.8;monocytes: 5.0" "Cell line enhanced" "Detected in some" "BEWO: 3.6;OE19: 7.8;RT4: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.18e-2)" "unprognostic (2.49e-1)" "unprognostic (6.58e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (4.91e-3)" "unprognostic (4.74e-2)" "unprognostic (4.48e-2)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.17e-1)" "unprognostic (2.61e-9)" "unprognostic (2.48e-2)" "unprognostic (2.19e-2)" "unprognostic (4.99e-2)" "unprognostic (8.03e-2)" 1.8 5.7 3.4 1.8 3.3 5.0 1.8 1.0 3.0 1.9 2.2 1.5 0.7 1.6 1.7 1.0 1.3 1.5 1.2 2.7 2.6 0.7 0.5 1.6 0.4 2.4 2.3 0.9 0.6 0.3 1.6 2.1 2.0 2.1 1.8 0.1 1.4 1.5 2.0 7.9 39.0 2.7 2.5 4.1 0.9 2.6 2.9 0.6 2.0 0.6 0.3 1.7 1.3 1.6 0.4 0.0 2.4 0.0 0.5 0.3 3.6 0.1 1.0 0.2 0.2 2.5 0.2 0.2 0.2 0.4 1.0 0.5 0.0 1.9 0.2 0.1 0.0 0.2 0.4 0.4 0.8 0.4 0.1 0.4 1.1 0.4 0.5 0.4 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.1 7.8 0.5 0.0 0.4 0.0 1.1 2.7 1.0 0.2 0.1 0.1 0.2 0.2 0.0 1.3 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.8 1.8 0.0 0.0 3.0 3.0 0.0 4.4 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 8.8 0.0 5.0 0.3 0.1 1.1 3.4 3.3 1.0 3.0 2.7 2.6 2.4 2.3 2.0 2.5 2.9 1.6 0.6 0.0 0.6 0.7 0.3 0.4 1.0 0.6 0.6 0.1 1.6 1.5 1.6 0.0 1.5 0.0 0.0 0.5 2.1 6.5 1.9 1.6 27.0 2.4 1.0 1.5 1.2 0.0 3.2 0.9 23.2 0.6 0.0 1.1 5.7 0.1 1.1 0.0 12.5 0.0 3.4 5.4 0.0 17.4 10.1 18.3 1.2 12.5 0.0 15.0 4.8 0.3 0.0 1.5 0.4 1.0 2.6 0.7 0.5 0.4 112.6 0.0 1.5 0.0 0.0 1.1 0.3 1.0 0.9 0.3 0.4 8.2 1.5 0.6 2.5 1.6 PPP1CB "MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 985.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 90.9 75.2 55.8 74.7 73.5 119.1 110.5 55.6 74.9 148.6 67.8 109.2 84.8 138.4 104.0 245.7 113.5 103.1 185.2 54.3 73.8 84.4 70.5 73.3 60.4 73.9 61.2 92.7 76.2 126.9 45.9 74.8 74.5 149.1 92.9 70.8 114.6 123.4 386.0 73.7 76.0 159.7 71.8 65.8 81.7 47.6 63.5 71.3 78.8 262.8 91.1 118.0 104.1 88.2 186.0 114.6 391.1 121.7 130.8 121.0 227.0 97.7 110.6 92.2 91.0 102.6 106.9 147.5 119.2 101.5 102.7 111.4 112.6 129.9 109.8 235.9 58.2 111.3 130.1 111.5 284.3 127.8 50.5 93.5 181.3 100.1 207.8 97.4 113.8 77.0 103.6 140.4 123.3 93.2 136.9 110.3 128.3 141.8 89.8 132.2 344.9 112.7 304.3 220.6 106.7 131.3 151.4 166.2 136.2 111.4 80.4 70.6 137.6 122.6 134.6 89.3 119.0 100.4 171.0 299.8 130.1 135.0 93.5 72.4 59.4 84.9 39.8 96.7 50.8 38.6 59.3 46.8 65.4 31.6 51.8 58.8 103.6 61.4 115.2 49.8 74.3 52.8 55.8 73.5 55.6 74.9 54.3 73.8 73.9 61.2 74.5 71.8 63.5 88.2 172.2 93.0 80.6 59.4 147.8 492.1 176.7 101.5 64.9 62.4 208.0 117.0 352.1 112.9 124.1 310.8 27.1 129.6 210.4 324.5 244.6 297.0 514.0 330.2 245.7 129.3 283.0 200.2 68.5 210.5 202.1 147.8 78.5 258.9 146.6 91.2 137.8 108.7 114.7 163.2 71.8 144.2 111.9 182.6 985.1 406.2 196.7 238.1 336.2 59.0 137.9 116.6 55.6 64.3 68.4 236.8 181.3 302.0 100.9 364.9 106.6 227.4 213.3 65.2 631.1 225.8 264.8 55.2 66.6 135.6 458.0 392.9 237.7 65.8 154.4 498.9 SPDYA "Ringo3, SPDY1, SPY1" ENSG00000163806 "Speedy/RINGO cell cycle regulator family member A" Q5MJ70 2 28782517-28850611 "Predicted intracellular proteins" "Cell cycle, DNA damage" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "testis: 32.5" "Group enriched" "Detected in many" 4 "Early spermatids: 58.8;Spermatocytes: 225.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 2.6;THP-1: 2.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035162, HPA066214" Enhanced Supported Nucleoplasm NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA035162: AB_2674501, HPA066214: AB_2685636" "unprognostic (3.41e-2)" "unprognostic (3.20e-3)" "unprognostic (2.45e-1)" "unprognostic (3.53e-2)" "unprognostic (4.21e-2)" "unprognostic (4.04e-3)" "unprognostic (1.10e-4)" "unprognostic (3.04e-3)" "unprognostic (1.95e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.99e-2)" "unprognostic (1.66e-13)" "unprognostic (8.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.85e-1)" "unprognostic (5.55e-5)" 0.8 0.9 0.2 0.2 0.2 0.6 0.7 0.2 0.3 1.8 0.0 0.8 0.5 0.7 0.0 0.9 0.9 0.5 0.8 0.3 0.0 1.7 1.4 0.7 0.5 0.0 0.0 1.4 0.8 0.0 1.4 0.2 0.0 1.7 0.0 1.0 0.7 0.0 0.3 1.6 0.9 0.0 0.0 1.8 0.8 32.5 0.1 0.0 1.2 0.0 0.0 0.7 1.0 0.1 0.4 0.2 0.7 1.6 0.0 0.0 0.8 0.4 0.0 0.1 0.0 0.4 0.3 0.3 0.5 0.0 0.4 1.0 0.1 0.0 0.1 0.2 0.4 0.3 1.0 1.3 0.0 0.5 0.7 0.1 0.0 0.1 0.2 0.3 0.0 0.3 0.2 0.6 0.3 0.2 0.1 2.6 0.2 0.1 0.1 0.3 1.2 0.4 0.5 0.3 0.5 0.3 0.8 1.0 0.3 0.7 0.3 2.5 0.1 1.2 1.0 0.6 0.6 0.3 0.7 0.7 0.3 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.5 3.2 0.5 6.5 2.6 0.3 1.0 0.4 0.6 0.8 3.7 3.8 0.6 0.0 1.4 1.8 6.2 0.1 2.1 2.1 0.0 0.7 58.8 9.9 2.7 1.4 0.0 0.4 9.0 0.5 0.2 1.9 4.1 12.2 2.5 0.8 1.8 0.1 0.4 0.0 6.0 0.0 0.0 0.3 3.1 29.1 2.5 6.7 0.0 1.9 0.8 0.1 0.0 9.0 6.0 0.8 0.3 2.2 2.9 1.2 0.5 0.1 1.6 1.4 6.6 9.0 1.7 225.0 9.6 1.8 0.1 0.5 3.8 0.5 0.5 2.1 TRMT61B FLJ20628 ENSG00000171103 "TRNA methyltransferase 61B" Q9BVS5 2 28849821-28870309 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026747, HPA026751" Enhanced Uncertain Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA026747: AB_1848782, HPA026751: AB_1848784" "unprognostic (1.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.63e-3)" "unprognostic (2.05e-2)" "unprognostic (3.32e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.36e-2)" "unprognostic (2.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-2)" "prognostic favorable (9.61e-5)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (5.38e-2)" "unprognostic (2.34e-1)" 8.8 13.1 9.8 8.5 9.9 9.2 13.1 12.1 17.0 9.4 12.0 8.4 14.1 10.1 14.0 8.6 8.1 7.2 15.2 9.8 9.9 14.4 12.6 6.6 11.0 9.7 9.8 9.4 7.0 15.1 9.0 8.9 10.0 10.6 9.3 9.4 8.7 7.9 13.8 8.7 14.1 10.3 9.8 8.7 9.2 7.4 9.7 10.2 9.1 16.6 9.1 10.7 7.5 10.6 28.5 16.7 16.7 29.6 22.3 19.0 20.1 16.5 20.3 20.6 19.2 19.3 15.0 29.9 14.8 14.5 24.7 21.7 23.5 20.1 21.3 22.6 15.8 9.1 13.6 25.7 25.2 19.4 10.0 19.5 22.0 16.4 22.2 15.2 20.0 19.1 18.9 11.2 17.2 11.3 17.3 29.6 31.0 33.6 26.7 12.7 26.9 26.1 18.2 18.2 28.1 29.8 17.8 27.8 28.5 13.9 14.2 6.7 15.8 13.7 23.1 13.6 21.0 13.7 24.2 46.6 18.1 28.9 18.8 0.0 8.0 3.5 11.2 8.5 13.8 14.5 12.4 12.0 7.8 14.1 13.7 9.9 1.1 17.7 7.1 8.3 14.7 7.4 9.8 9.9 12.1 17.0 9.8 9.9 9.7 9.8 10.0 9.8 9.7 10.6 10.2 16.0 8.7 18.3 17.7 18.1 11.0 23.7 17.1 10.8 9.9 10.2 2.8 11.5 14.7 9.2 6.2 22.1 11.8 4.5 15.6 14.5 9.3 9.4 11.8 8.5 4.8 10.9 38.0 10.2 13.8 10.8 21.4 7.7 9.5 15.8 7.5 11.5 9.2 6.7 34.8 9.8 20.3 7.3 8.2 3.6 8.7 7.0 7.2 7.5 11.0 10.3 8.2 36.2 32.2 10.3 8.5 10.5 13.5 7.6 23.6 30.3 15.0 21.6 6.6 12.2 10.6 24.1 9.7 15.3 15.8 8.8 12.4 15.9 12.1 7.3 WDR43 "KIAA0007, NET12, UTP5" ENSG00000163811 "WD repeat domain 43" Q15061 2 28894667-28948219 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 383.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044733 Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "HPA044733: AB_10959613" "unprognostic (3.39e-1)" "unprognostic (1.06e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (2.76e-2)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.66e-5)" "unprognostic (7.00e-2)" "unprognostic (1.94e-2)" "unprognostic (1.60e-1)" "unprognostic (2.33e-3)" "unprognostic (2.66e-2)" "unprognostic (2.56e-3)" "unprognostic (6.20e-2)" "unprognostic (8.66e-2)" "unprognostic (6.30e-2)" "unprognostic (1.11e-1)" 22.1 11.3 7.3 17.5 8.0 42.3 23.6 11.6 8.4 16.5 9.0 16.6 12.1 15.5 9.0 18.2 14.6 12.1 9.6 7.4 8.8 12.3 23.0 11.1 20.3 7.6 7.9 17.0 22.8 15.6 7.4 17.5 8.8 12.1 16.5 13.3 11.5 12.0 55.6 17.6 11.5 19.1 8.4 14.4 12.8 19.8 8.9 18.5 14.5 15.7 24.2 24.2 11.9 10.4 108.5 90.7 42.9 57.0 37.7 47.4 127.1 69.1 44.7 61.4 44.8 92.6 48.6 138.2 50.1 57.9 77.1 54.4 116.6 103.4 98.1 57.9 81.8 122.4 65.5 135.6 57.1 160.9 56.3 49.3 60.5 97.0 164.0 29.3 58.9 52.5 130.2 52.5 54.4 63.7 127.0 89.6 111.0 74.7 59.3 96.3 130.1 95.1 43.4 111.8 61.6 63.8 40.9 67.6 75.1 40.5 30.4 40.5 53.5 63.5 73.1 50.8 118.8 64.2 95.0 383.1 44.2 101.3 60.8 0.4 11.5 8.7 12.5 13.6 22.7 17.3 15.5 14.0 14.8 16.5 19.5 15.0 2.5 22.0 15.5 12.6 14.0 11.7 7.3 8.0 11.6 8.4 7.4 8.8 7.6 7.9 8.8 8.4 8.9 10.4 40.8 51.3 50.7 17.6 54.1 167.7 93.1 41.2 82.0 29.8 53.1 49.7 36.5 37.1 71.5 25.8 22.9 39.0 35.3 21.8 15.6 55.7 88.7 46.1 75.6 40.5 20.9 36.6 28.6 46.2 44.4 56.5 34.7 82.7 45.5 27.5 20.3 49.6 24.3 21.9 29.0 32.1 26.4 21.6 29.6 125.8 37.6 30.3 33.8 30.9 31.8 17.7 27.8 34.2 26.5 55.2 15.7 29.3 42.8 50.8 15.0 19.6 29.7 42.3 6.6 82.7 46.4 33.6 38.6 67.8 148.0 40.4 38.6 41.4 53.8 58.5 TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 34.9;choroid plexus: 25.2;fallopian tube: 20.1" "Group enriched" "Detected in some" 4 "dendritic cells: 20.1;Endometrial ciliated cells: 65.4;Respiratory ciliated cells: 30.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;JURKAT: 1.2;NB-4: 1.3" "Low region specificity" "Detected in many" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "HPA037561: AB_10670384, HPA037562: AB_2675545, HPA075216: " "unprognostic (8.35e-5)" "unprognostic (2.85e-3)" "unprognostic (1.41e-1)" "unprognostic (7.01e-3)" "unprognostic (6.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-3)" "unprognostic (3.93e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-3)" "unprognostic (5.92e-2)" "unprognostic (3.94e-11)" "unprognostic (3.75e-2)" "unprognostic (4.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.81e-3)" 0.1 1.2 4.5 0.6 11.5 1.9 0.2 10.6 2.3 0.5 25.2 0.3 0.5 0.6 0.1 0.4 20.1 0.3 2.8 4.5 7.6 0.1 0.2 2.8 0.8 19.2 34.9 0.5 0.3 0.0 1.1 0.3 17.3 0.2 0.2 0.2 0.2 0.1 1.2 0.3 0.4 0.5 12.5 2.0 1.0 1.3 10.6 0.2 0.1 3.0 0.7 0.2 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.7 0.0 0.6 0.1 0.2 0.6 2.3 0.1 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.3 0.3 0.0 0.3 1.3 1.0 0.4 0.1 0.0 0.3 0.6 0.3 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.5 4.5 11.5 10.6 2.3 4.5 7.6 19.2 34.9 17.3 12.5 10.6 5.3 0.3 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 65.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.2 30.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.6 0.5 0.0 0.0 PCARE "C2orf71, FLJ34931, RP54" ENSG00000179270 "Photoreceptor cilium actin regulator" A6NGG8 2 29060976-29074523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "retina: 28.5" "Cell type enriched" "Detected in single" 20 "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 79: Retina - Phototransduction" "Cluster 43: Cardiomyocytes - Nuclear processes" "unprognostic (2.28e-3)" "unprognostic (1.23e-1)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (1.88e-1)" "unprognostic (5.88e-3)" "unprognostic (6.68e-3)" "unprognostic (1.21e-1)" "unprognostic (6.61e-2)" "unprognostic (3.81e-2)" "unprognostic (2.37e-1)" "unprognostic (2.08e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-4)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.5 0.4 0.0 0.1 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.5 0.2 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLIP4 "FLJ21069, RSNL2" ENSG00000115295 "CAP-Gly domain containing linker protein family member 4" Q8N3C7 2 29097705-29189643 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.2;Inhibitory neurons: 142.8;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 247.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 25.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 83.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043366, HPA056246" Uncertain Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA043366: AB_10963051, HPA056246: AB_2683078" "unprognostic (1.97e-2)" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (2.47e-3)" "unprognostic (3.64e-1)" "unprognostic (6.82e-2)" "unprognostic (1.15e-2)" "unprognostic (8.82e-3)" "unprognostic (3.62e-1)" "unprognostic (4.32e-2)" "unprognostic (2.73e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.59e-3)" "unprognostic (6.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.99e-2)" 19.3 9.8 15.1 9.5 24.7 1.9 14.2 20.6 19.7 14.3 18.3 20.8 4.8 13.7 8.7 23.4 15.5 13.4 30.0 15.2 18.9 9.0 4.5 18.7 10.2 20.6 21.8 22.7 6.3 14.3 20.0 16.4 20.9 16.6 7.0 17.9 13.9 15.2 71.9 30.9 10.7 18.6 18.6 10.0 10.2 17.5 18.1 13.5 33.5 43.8 10.7 20.8 19.9 31.4 82.3 22.6 3.4 12.1 31.4 47.0 0.1 31.8 54.4 17.5 19.9 0.7 52.7 10.2 15.9 55.1 69.9 33.0 3.6 24.7 24.8 18.9 5.4 0.0 29.1 1.2 79.7 0.0 16.2 33.3 61.3 23.2 83.8 62.8 12.4 7.4 0.5 31.5 26.7 0.6 7.9 3.6 0.9 4.8 5.0 0.1 20.1 1.6 32.0 14.4 5.3 13.7 27.6 11.2 29.0 3.3 0.0 4.9 39.4 4.1 31.6 13.7 13.8 16.2 0.1 0.1 19.0 0.0 12.7 2.5 6.1 0.2 7.9 14.8 12.4 1.4 6.1 8.4 2.4 0.5 6.9 6.8 1.2 5.6 25.9 0.0 2.3 5.6 15.1 24.7 20.6 19.7 15.2 18.9 20.6 21.8 20.9 18.6 18.1 31.4 0.9 64.1 15.0 78.7 7.2 17.1 27.6 26.8 30.1 31.0 11.4 8.9 76.2 0.0 18.5 12.9 29.2 6.7 18.6 0.1 3.9 10.7 169.2 16.1 8.4 2.5 0.0 2.5 75.1 9.1 1.7 26.5 4.1 12.9 5.1 13.1 1.4 1.8 9.9 20.2 142.8 0.0 8.2 36.1 6.0 91.1 27.4 25.9 8.8 15.9 17.5 18.7 19.6 130.2 247.2 22.1 0.0 24.0 30.9 25.8 0.0 5.9 32.1 17.9 13.1 24.2 9.2 9.4 1.6 29.7 27.3 21.5 21.9 16.4 0.2 24.2 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 YPEL5 CGI-127 ENSG00000119801 "Yippee like 5" P62699 2 30146941-30160533 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 438.1" "Cell type enhanced" "Detected in all" "Late spermatids: 548.0;Plasma cells: 545.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042809 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA042809: AB_2678179" "unprognostic (7.22e-3)" "unprognostic (6.50e-3)" "unprognostic (9.16e-2)" "unprognostic (5.47e-2)" "unprognostic (4.88e-2)" "unprognostic (1.83e-2)" "unprognostic (3.60e-2)" "unprognostic (3.39e-2)" "unprognostic (1.95e-1)" "unprognostic (5.73e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-3)" "unprognostic (1.16e-2)" "unprognostic (7.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.67e-3)" 65.2 67.0 61.5 44.9 65.6 438.1 55.2 58.0 81.2 61.3 68.2 70.3 40.5 51.4 84.3 55.6 51.3 64.0 56.7 66.0 64.7 87.4 64.4 61.1 62.7 64.0 57.2 60.3 44.8 101.5 45.6 64.6 63.0 68.8 45.5 77.2 63.3 95.5 54.1 51.9 44.4 65.1 61.8 58.9 49.4 71.4 60.8 77.2 61.8 48.7 62.8 78.1 47.0 61.6 35.9 18.1 42.5 20.9 113.3 109.4 35.0 50.7 152.6 28.5 43.3 16.3 36.7 21.4 32.7 100.7 65.0 19.1 9.9 50.5 40.2 94.1 19.1 11.0 8.0 26.0 98.3 3.7 24.9 114.1 100.7 53.0 67.6 122.5 53.8 13.5 15.5 36.8 77.2 18.5 11.3 26.3 23.9 41.2 22.7 7.0 56.8 20.9 96.4 69.6 16.7 51.1 24.6 24.4 65.2 77.1 27.3 20.5 70.6 77.4 29.5 21.2 14.2 86.5 34.9 28.7 55.1 9.9 31.7 229.3 82.4 190.7 53.3 95.4 54.7 89.9 65.8 64.2 78.0 74.0 62.2 55.8 306.9 56.5 149.5 152.9 95.8 146.6 61.5 65.6 58.0 81.2 66.0 64.7 64.0 57.2 63.0 61.8 60.8 61.6 83.8 83.3 90.5 13.4 398.6 134.0 162.9 184.8 122.3 70.7 142.5 105.5 73.2 47.1 119.3 101.2 47.9 172.8 300.4 104.1 138.9 90.9 253.9 178.0 71.0 74.3 208.9 93.7 30.9 78.8 140.4 84.2 126.9 213.7 81.3 46.4 56.0 43.3 103.3 63.9 25.9 94.5 114.0 132.1 168.7 548.0 57.8 214.9 170.7 15.9 321.0 103.4 50.4 19.6 28.3 110.2 108.6 82.8 545.7 143.3 84.8 137.0 101.4 63.5 52.6 87.4 114.9 133.8 78.0 97.4 142.6 408.0 358.5 53.5 46.8 281.2 LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 210.6;Pancreatic endocrine cells: 298.9;Smooth muscle cells: 435.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.4;MAIT T-cell: 110.2;memory B-cell: 92.0;memory CD4 T-cell: 83.8;memory CD8 T-cell: 86.1;naive B-cell: 123.0;naive CD4 T-cell: 140.2;naive CD8 T-cell: 124.6;T-reg: 89.2" "Group enriched" "Detected in all" 7 "B-cells: 123.0;T-cells: 140.2" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 302.4;hTERT-RPE1: 150.6;U-2 OS: 95.1" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA034669: AB_10600820" "unprognostic (2.13e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (4.77e-3)" "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (3.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.25e-2)" "unprognostic (7.91e-3)" "unprognostic (1.67e-1)" 35.2 10.3 8.4 57.4 7.9 28.6 32.0 13.7 22.4 45.6 18.4 27.4 14.4 83.0 27.0 17.0 41.7 44.9 119.3 15.2 33.9 39.3 15.0 130.7 117.8 23.0 17.4 63.3 14.4 84.8 16.7 54.5 18.4 27.3 18.1 70.8 63.9 26.3 14.3 30.3 41.2 48.2 11.2 83.5 22.8 9.8 14.4 125.7 68.9 20.4 100.9 35.5 22.7 11.8 0.1 11.4 14.0 2.5 3.6 2.2 1.1 14.5 19.1 3.8 0.6 59.4 15.2 28.6 33.3 302.4 3.8 19.5 81.1 0.8 0.6 41.3 3.4 4.6 12.2 0.2 10.9 0.4 4.0 13.0 1.1 5.0 0.3 150.6 0.7 19.0 14.6 0.2 14.2 0.2 32.3 0.4 84.6 2.6 0.6 33.1 75.4 9.7 2.6 5.0 3.9 10.0 23.7 2.3 1.0 49.7 0.1 1.2 18.9 26.8 95.1 52.0 1.8 53.8 3.3 2.7 11.9 1.8 8.4 0.7 0.7 1.1 112.4 1.2 110.2 92.0 83.8 86.1 0.8 123.0 140.2 124.6 4.0 18.9 3.2 12.1 89.2 110.4 8.4 7.9 13.7 22.4 15.2 33.9 23.0 17.4 18.4 11.2 14.4 11.8 46.9 109.0 20.0 0.7 167.3 12.4 64.5 51.7 16.5 41.2 13.0 125.0 65.1 12.8 40.8 25.8 210.6 18.3 152.2 6.0 13.7 85.4 39.4 110.5 18.0 81.8 23.8 85.9 2.2 56.9 10.8 54.7 23.4 45.2 15.8 2.3 23.6 1.2 33.2 8.4 16.4 9.3 30.5 10.0 23.1 144.5 10.5 14.3 23.2 14.0 6.7 13.1 163.7 9.5 0.7 298.9 8.7 26.7 26.3 95.3 0.7 21.7 67.8 45.4 177.5 36.3 435.6 0.7 6.6 9.1 10.7 9.3 205.3 8.8 6.3 56.8 LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 67.3;Inhibitory neurons: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" Cytosol "HPA031880: AB_10610002, HPA049217: AB_2680678" "unprognostic (6.60e-2)" "unprognostic (2.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.52e-3)" "unprognostic (4.10e-1)" "prognostic unfavorable (9.67e-4)" "prognostic unfavorable (8.72e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-2)" "unprognostic (7.11e-3)" "unprognostic (2.85e-2)" "unprognostic (4.14e-2)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (3.93e-3)" "unprognostic (1.10e-1)" 4.2 4.9 6.1 5.0 6.7 9.9 5.3 10.8 9.3 6.7 3.4 7.8 12.3 7.2 9.8 5.1 6.1 6.2 11.3 5.3 7.8 9.5 8.6 5.1 5.4 2.9 3.3 4.9 5.9 6.3 3.2 4.3 3.1 7.8 7.9 10.6 4.6 7.0 9.6 6.6 9.5 8.7 0.8 5.3 5.3 8.3 7.0 6.4 10.9 4.1 5.4 4.9 3.7 10.2 16.9 21.6 11.3 19.3 2.6 5.7 16.3 11.8 11.7 12.3 10.3 21.8 19.0 10.5 10.7 18.4 15.2 18.3 38.8 16.0 12.1 13.6 13.0 19.4 12.8 21.6 12.0 28.1 14.3 4.6 12.4 13.0 18.0 8.0 8.7 6.0 18.3 9.5 9.6 12.8 16.1 16.5 12.5 13.6 12.4 15.6 22.9 21.8 9.7 24.7 13.1 20.5 26.4 17.4 15.7 7.7 12.6 9.5 10.0 22.1 18.2 12.4 18.9 7.0 16.2 23.2 22.7 20.1 17.3 15.9 2.3 5.0 5.2 3.8 6.2 7.5 8.3 6.7 2.8 9.7 11.7 11.5 7.2 4.6 3.6 2.0 4.2 3.0 6.1 6.7 10.8 9.3 5.3 7.8 2.9 3.3 3.1 0.8 7.0 10.2 6.5 9.6 6.9 27.1 11.4 7.1 5.0 8.4 6.8 15.5 6.9 5.3 20.1 18.6 8.7 14.7 27.1 5.2 6.7 10.4 0.0 7.7 3.9 12.0 7.0 7.7 13.1 10.3 67.3 16.4 5.3 6.7 3.1 9.4 3.8 11.6 8.6 21.5 6.1 15.2 86.8 14.3 0.0 5.7 3.9 1.4 5.6 3.4 5.4 45.0 2.4 7.9 5.2 50.8 37.3 12.9 8.6 9.1 5.2 5.4 21.4 12.1 16.6 18.2 6.6 10.9 16.3 13.9 21.0 7.9 6.7 1.9 9.1 10.9 17.0 4.7 CAPN13 FLJ23523 ENSG00000162949 "Calpain 13" Q6MZZ7 2 30722771-30820542 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 29.2;stomach 1: 28.5" "Cell type enhanced" "Detected in many" "Club cells: 76.6;Gastric mucus-secreting cells: 50.0;Proximal enterocytes: 35.2;Undifferentiated cells: 18.1;Urothelial cells: 19.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "RT4: 9.3;SK-BR-3: 21.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA029496, HPA029497, HPA030034" Uncertain Approved Nucleoplasm NA NA "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA029496: AB_2673072, HPA029497: AB_2673073, HPA030034: AB_2673281" "unprognostic (7.42e-2)" "unprognostic (1.19e-1)" "unprognostic (7.01e-3)" "unprognostic (1.96e-1)" "unprognostic (8.56e-2)" "unprognostic (1.51e-1)" "unprognostic (1.68e-1)" "unprognostic (1.32e-3)" "unprognostic (2.17e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-1)" "unprognostic (1.96e-2)" "unprognostic (3.64e-1)" "unprognostic (3.32e-2)" "unprognostic (5.03e-2)" "unprognostic (4.28e-3)" 0.0 0.0 0.8 0.0 1.4 0.0 7.2 0.9 1.3 9.7 1.0 11.4 20.8 0.2 0.3 0.9 1.1 2.8 0.0 0.7 0.8 2.5 0.2 7.2 0.0 1.1 1.3 0.0 3.6 0.4 0.2 0.0 1.0 3.8 24.6 0.0 1.2 0.1 0.0 0.2 29.2 0.2 1.0 0.1 28.5 0.1 1.1 0.0 0.0 0.0 0.6 4.1 0.5 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 9.3 0.1 0.4 0.0 21.9 0.0 0.7 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.4 0.9 1.3 0.7 0.8 1.1 1.3 1.0 1.0 1.1 2.3 0.0 6.4 3.1 0.3 0.0 0.0 10.2 3.5 4.0 0.0 4.2 1.8 1.3 0.0 76.6 1.8 0.0 0.0 0.0 16.9 0.0 1.3 0.8 2.0 0.0 0.1 15.0 0.0 0.3 5.3 0.0 0.6 50.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 1.5 12.0 6.1 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 8.4 1.9 6.2 0.0 0.0 2.7 35.2 0.2 12.4 0.0 0.0 0.0 6.1 0.0 0.1 1.4 0.0 0.0 0.1 0.0 18.1 19.4 GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.3" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 21.6;Excitatory neurons: 29.1;Inhibitory neurons: 79.2;Proximal enterocytes: 21.9;Proximal tubular cells: 45.5" "Cancer enriched" "Detected in many" 7 "renal cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cell line enhanced" "Detected in many" "A549: 28.6;RPMI-8226: 32.3;RPTEC TERT1: 41.3;RT4: 35.3;SCLC-21H: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 27000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Nucleoplasm "HPA030138: AB_2673332" "unprognostic (5.69e-2)" "unprognostic (1.35e-1)" "unprognostic (2.05e-2)" "unprognostic (2.82e-3)" "unprognostic (3.85e-2)" "unprognostic (2.10e-2)" "unprognostic (3.32e-1)" "unprognostic (7.58e-2)" "unprognostic (1.96e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.18e-3)" "unprognostic (5.18e-3)" "unprognostic (2.67e-2)" "unprognostic (2.56e-1)" "unprognostic (9.51e-3)" 1.2 1.5 3.9 1.0 10.6 5.9 0.8 2.0 4.5 1.3 3.6 0.3 0.5 0.3 0.3 11.8 1.2 2.2 0.3 2.9 3.2 41.3 1.3 0.6 2.2 1.7 6.7 0.1 3.1 4.0 5.9 0.0 0.8 1.6 0.1 0.6 1.2 0.0 0.1 2.1 3.3 0.7 1.8 2.4 0.5 2.5 10.9 0.4 0.9 0.4 4.8 2.3 1.3 3.3 23.6 28.6 0.0 0.0 0.0 0.0 0.0 7.9 4.1 4.9 0.6 0.0 0.0 22.1 7.8 0.4 0.0 0.0 1.0 1.0 0.8 0.6 2.8 12.1 0.0 0.0 0.0 18.2 0.0 0.1 4.5 0.0 17.0 0.2 0.0 0.6 0.0 19.0 0.0 10.7 0.1 0.0 12.6 0.0 0.0 15.5 0.0 32.3 41.3 35.3 24.4 18.3 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 19.6 0.0 0.5 1.9 6.2 0.1 0.0 11.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 3.9 10.6 2.0 4.5 2.9 3.2 1.7 6.7 0.8 1.8 10.9 3.3 2.2 0.0 0.0 1.0 1.4 2.8 4.1 5.3 21.6 0.3 0.6 2.4 1.1 0.0 6.2 9.2 0.0 0.0 0.0 0.3 13.7 2.9 5.7 0.0 0.1 1.2 0.0 0.0 29.1 0.4 0.0 1.1 0.5 0.4 0.0 0.0 8.2 0.2 0.1 0.0 79.2 0.9 2.0 0.6 0.3 12.0 0.0 0.4 0.0 2.8 0.0 0.2 0.0 4.0 8.7 2.6 0.0 0.0 3.1 14.2 21.9 45.5 1.1 0.4 6.6 0.4 2.2 3.4 6.9 9.2 0.9 0.0 0.4 0.2 1.8 5.1 CAPN14 ENSG00000214711 "Calpain 14" A8MX76 2 31173056-31233858 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "esophagus: 144.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.2;Inhibitory neurons: 4.2;Squamous epithelial cells: 8.2;Urothelial cells: 15.5" "Cancer enhanced" "Detected in some" "cervical cancer: 2.9;head and neck cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RT4: 1.1;U-266/70: 3.4" "Not detected" "Not detected" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (5.81e-3)" "unprognostic (1.20e-1)" "unprognostic (4.57e-2)" "unprognostic (1.88e-2)" "unprognostic (3.85e-2)" "unprognostic (3.30e-1)" "unprognostic (3.61e-2)" "unprognostic (4.67e-2)" "unprognostic (1.71e-1)" "unprognostic (3.14e-1)" "unprognostic (3.77e-1)" "unprognostic (1.60e-1)" "unprognostic (3.71e-4)" "unprognostic (8.42e-2)" "unprognostic (6.84e-2)" "unprognostic (1.91e-1)" "unprognostic (4.47e-4)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 144.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.5 0.1 0.6 0.8 0.1 0.0 1.7 0.0 0.7 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.6 0.8 0.1 0.2 0.0 0.0 3.2 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 1.7 4.2 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.5 0.5 0.0 2.2 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.2 8.2 0.0 1.4 0.1 0.0 0.1 15.5 EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;esophagus: 43.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Hepatic stellate cells: 120.3;Syncytiotrophoblasts: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.8;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.8" "Cell line enhanced" "Detected in many" "BJ: 79.7;BJ hTERT+: 192.2;HEL: 77.4;U-266/70: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Approved "Plasma membrane" NA NA 15000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (3.44e-1)" "unprognostic (8.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (5.49e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.72e-2)" "unprognostic (9.92e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (4.88e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-3)" "unprognostic (4.92e-3)" 2.5 9.1 20.5 5.9 29.5 1.9 3.2 10.5 38.7 5.5 1.1 2.5 1.6 4.4 3.0 43.9 4.5 3.4 15.9 29.5 18.5 20.0 11.0 5.7 6.8 11.7 17.8 2.5 1.3 21.1 9.1 11.7 13.9 5.5 1.7 9.0 5.9 4.4 2.3 3.1 3.7 4.6 9.6 7.3 2.2 1.3 31.1 2.7 3.2 5.1 11.1 6.6 6.0 26.2 1.8 8.4 4.5 3.9 7.5 11.3 0.7 79.7 192.2 7.5 6.9 0.0 0.9 0.6 2.9 26.0 6.5 0.8 0.2 5.2 5.3 3.2 7.1 77.4 0.4 0.0 25.7 0.0 0.2 18.1 2.3 7.3 3.0 20.0 0.1 0.2 0.3 0.4 5.6 12.6 1.0 0.1 17.7 0.0 4.3 2.8 0.3 1.8 5.8 8.9 2.2 12.1 0.8 1.3 0.0 14.1 1.2 0.0 0.0 5.8 5.4 0.3 6.5 48.7 6.5 0.1 14.8 0.0 12.4 0.6 0.5 0.5 2.1 1.0 1.1 20.8 1.0 1.4 0.5 5.6 0.9 0.5 1.2 0.8 2.8 0.0 0.5 10.2 20.5 29.5 10.5 38.7 29.5 18.5 11.7 17.8 13.9 9.6 31.1 26.2 1.9 0.0 0.0 2.6 16.2 0.8 1.8 1.7 10.2 9.7 0.6 6.2 24.3 5.7 0.9 0.0 0.0 4.1 0.6 0.0 0.0 0.5 0.1 0.7 2.3 8.4 1.8 6.1 17.1 0.2 8.4 3.3 1.1 0.5 0.0 0.4 120.3 5.0 1.7 0.0 11.1 0.1 0.0 16.1 0.4 0.0 1.2 5.9 0.0 4.7 1.1 9.0 0.0 22.6 5.4 0.2 0.1 3.0 5.8 2.6 0.0 0.2 0.4 5.9 19.7 3.0 7.0 0.6 2.7 10.7 0.9 43.9 1.4 0.7 0.1 4.7 XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 42.2;intestine: 49.5;liver: 68.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 262.1;Distal enterocytes: 143.5;Hepatocytes: 46.9;Paneth cells: 48.8;Proximal enterocytes: 96.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 8.2;HBEC3-KT: 20.0;hTERT-HME1: 31.0;U-251 MG: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" No No 77000 "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm Nucleoli "HPA062641: AB_2684816, HPA069323: AB_2686121" "unprognostic (8.58e-2)" "unprognostic (4.07e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (4.38e-3)" "unprognostic (7.48e-3)" "unprognostic (3.55e-1)" "unprognostic (3.60e-2)" "unprognostic (3.95e-3)" "unprognostic (3.51e-2)" "unprognostic (1.24e-6)" "unprognostic (2.25e-1)" "unprognostic (5.25e-2)" "unprognostic (2.54e-1)" "prognostic favorable (8.73e-6)" 0.2 0.0 0.0 4.8 0.0 0.1 42.2 0.3 0.0 0.3 0.4 11.1 44.9 0.9 2.3 9.8 0.1 4.5 0.0 0.0 0.0 0.2 68.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.5 0.1 0.1 1.3 9.5 0.1 3.6 0.1 0.5 1.1 49.5 0.7 0.0 0.0 3.2 0.1 0.0 0.2 0.3 0.0 2.3 2.7 2.0 0.1 2.0 0.4 0.0 0.0 0.0 0.1 0.1 8.2 4.7 1.0 1.4 0.3 2.3 0.1 1.6 0.3 0.8 4.2 0.0 20.0 1.0 1.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 1.8 1.1 31.0 0.4 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.4 1.2 0.2 0.0 1.4 4.5 5.7 5.2 0.0 0.1 0.1 0.3 0.0 1.7 0.0 0.0 0.0 3.8 2.4 0.2 8.9 2.5 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 2.4 0.0 0.2 0.5 6.0 5.5 2.8 0.3 262.1 6.5 0.4 2.8 3.6 0.0 0.0 0.3 1.1 143.5 0.0 3.9 0.3 7.9 2.8 0.3 11.9 0.0 0.2 8.2 0.6 0.2 2.0 37.0 0.0 0.0 1.4 46.9 0.0 0.0 0.2 8.4 2.0 1.9 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 48.8 0.0 0.0 2.2 96.8 0.0 1.0 0.7 0.0 0.3 0.7 0.0 0.2 1.2 0.1 0.4 0.7 0.2 22.2 16.9 SRD5A2 ENSG00000277893 "Steroid 5 alpha-reductase 2" P31213 2 31522480-31580938 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Sexual differentiation" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "epididymis: 23.5;fallopian tube: 20.4;liver: 60.8;prostate: 16.8;seminal vesicle: 18.0" "Group enriched" "Detected in some" 5 "Early spermatids: 71.7;Endometrial ciliated cells: 29.6;Hepatocytes: 20.0;Late spermatids: 59.9" "Group enriched" "Detected in some" 6 "endometrial cancer: 1.1;liver cancer: 4.2;prostate cancer: 3.2" "Region enriched" "Detected in single" 11 "midbrain: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (6.75e-3)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-3)" "unprognostic (5.92e-3)" "unprognostic (3.37e-2)" "unprognostic (2.79e-3)" "unprognostic (6.56e-2)" "unprognostic (9.10e-2)" "unprognostic (1.39e-2)" "unprognostic (3.06e-2)" "unprognostic (9.79e-3)" "unprognostic (6.61e-6)" "unprognostic (4.37e-2)" "unprognostic (2.04e-1)" "unprognostic (3.85e-1)" "unprognostic (3.48e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 23.5 0.0 20.4 0.0 0.0 0.0 0.0 0.3 60.8 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 0.0 0.1 0.0 18.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.0 0.0 0.0 1.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.7 29.6 0.2 0.2 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.5 0.0 0.0 0.4 20.0 0.0 0.0 1.0 0.0 0.0 0.3 0.0 59.9 0.6 0.1 0.0 3.7 0.0 0.0 0.0 0.5 0.9 0.1 0.0 1.2 0.0 0.7 0.0 0.3 7.3 0.0 0.0 0.0 0.2 1.2 0.8 0.0 0.0 0.0 0.1 0.0 0.0 8.6 MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 115.0;Inhibitory neurons: 111.2;Microglial cells: 100.2;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 9100 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042603: AB_10806243, HPA057952: AB_2683562" "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.94e-5)" "unprognostic (1.02e-2)" "unprognostic (3.96e-2)" "unprognostic (2.24e-4)" "unprognostic (1.70e-2)" "unprognostic (6.73e-2)" "unprognostic (8.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (5.95e-9)" "unprognostic (6.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.77e-2)" "unprognostic (4.23e-2)" 17.2 23.7 15.0 23.2 13.7 45.7 14.7 14.0 14.1 15.1 9.9 17.5 16.7 14.4 16.7 33.6 13.1 13.4 36.3 13.4 13.7 16.4 35.9 13.9 31.9 14.2 14.2 10.7 17.3 14.6 11.9 20.6 13.9 14.2 20.7 11.7 16.8 13.6 58.8 19.2 16.7 19.5 13.4 20.3 17.3 62.2 14.4 31.5 12.5 36.5 34.2 26.3 19.3 16.8 87.7 37.4 40.5 37.8 34.8 49.4 73.0 73.6 45.7 41.1 31.5 51.0 48.2 92.4 23.2 50.6 54.2 43.4 48.4 63.9 54.0 61.8 26.4 67.0 22.8 62.7 48.6 67.7 53.7 37.2 40.7 40.6 40.7 46.7 65.1 21.8 49.0 41.4 72.2 38.3 81.5 137.8 60.0 74.9 46.2 54.4 46.0 71.4 81.8 83.6 34.2 63.3 38.0 90.7 59.2 33.9 38.2 80.4 61.0 57.0 63.4 45.8 82.1 42.8 69.8 79.7 51.7 96.1 45.7 1.8 16.6 17.1 7.5 23.4 5.7 9.6 9.2 9.0 24.4 7.5 6.6 6.5 13.4 12.6 27.9 9.1 17.1 10.1 15.0 13.7 14.0 14.1 13.4 13.7 14.2 14.2 13.9 13.4 14.4 16.8 6.7 6.4 13.3 70.8 19.1 27.8 17.2 10.3 17.6 15.3 10.6 6.3 4.7 12.8 9.3 11.0 16.7 13.3 9.0 8.3 1.9 4.9 3.6 5.2 9.1 11.3 13.1 18.3 115.0 2.6 10.5 9.6 11.2 8.7 10.1 10.2 14.3 14.0 10.1 11.8 111.2 7.0 8.2 19.2 18.4 3.0 13.1 15.2 12.4 100.2 21.8 4.6 14.4 106.1 134.4 7.5 8.3 8.6 11.2 19.7 8.5 2.4 8.8 10.5 6.6 12.5 6.0 12.2 6.4 26.9 16.6 16.6 12.8 7.9 10.4 16.8 DPY30 "Cps25, HDPY-30, Saf19" ENSG00000162961 "Dpy-30 histone methyltransferase complex regulatory subunit" Q9C005 2 31867809-32039805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 388.8;Respiratory ciliated cells: 396.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043761 Supported Supported "Nucleoplasm,Golgi apparatus" NA NA 29000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Golgi apparatus" "HPA043761: AB_10960501" "unprognostic (2.76e-2)" "unprognostic (1.48e-1)" "unprognostic (2.52e-2)" "unprognostic (1.07e-2)" "unprognostic (1.64e-1)" "unprognostic (4.57e-3)" "unprognostic (4.14e-3)" "unprognostic (1.91e-1)" "unprognostic (7.87e-2)" "unprognostic (1.01e-3)" "unprognostic (1.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (2.70e-1)" "unprognostic (6.77e-2)" "unprognostic (2.79e-2)" "unprognostic (1.49e-1)" 40.2 75.2 66.9 34.3 68.6 31.4 61.3 72.1 84.4 53.2 73.6 50.9 43.4 38.3 78.3 60.2 90.5 42.4 46.7 68.4 73.6 79.1 84.8 44.1 51.8 71.6 71.5 42.7 48.1 58.3 50.9 43.9 73.6 57.3 46.4 33.3 64.6 47.0 48.8 49.7 44.4 37.4 73.2 36.1 46.8 22.6 69.1 52.3 81.6 45.4 49.3 51.8 50.0 77.5 201.8 136.8 100.8 78.1 86.7 128.8 134.9 102.1 90.8 81.2 79.5 197.2 158.3 123.2 102.2 90.8 148.3 79.9 93.1 118.6 88.1 146.4 149.5 110.8 89.7 225.5 76.5 114.3 66.8 87.4 135.6 87.4 76.9 109.1 130.4 55.1 132.5 85.3 125.6 219.4 128.8 228.9 139.2 184.3 140.5 104.0 118.9 155.7 144.2 137.1 162.5 115.9 101.2 141.1 143.6 118.2 98.3 82.1 100.5 73.9 119.1 69.2 125.4 99.9 161.3 166.2 77.6 123.2 91.7 177.6 101.0 150.8 95.5 99.9 116.5 165.9 133.5 119.4 100.5 135.6 118.1 112.0 117.3 105.8 112.8 91.5 200.3 130.6 66.9 68.6 72.1 84.4 68.4 73.6 71.6 71.5 73.6 73.2 69.1 77.5 65.7 51.3 61.5 10.1 61.7 98.0 107.7 233.5 53.5 17.9 110.5 135.1 71.3 80.1 140.8 103.0 0.0 190.2 41.0 84.2 283.7 114.3 64.5 388.8 59.7 62.9 92.1 55.5 16.0 117.2 252.4 63.1 44.4 107.3 46.9 65.1 63.1 102.7 123.5 21.9 17.7 107.6 175.0 65.4 67.2 18.5 72.4 58.7 65.8 13.1 106.8 50.8 55.6 13.6 26.7 125.7 117.8 88.0 40.6 130.5 138.4 296.7 396.4 26.8 85.5 52.4 108.4 65.7 57.4 72.0 122.6 138.7 67.3 67.7 109.0 127.5 SPAST "ADPSP, FSP2, KIAA1083, SPG4" ENSG00000021574 Spastin Q9UBP0 2 32063556-32157637 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Differentiation, Neurogenesis" "Allosteric enzyme, Developmental protein, Isomerase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 55.2;Oligodendrocyte precursor cells: 59.3;Oligodendrocytes: 62.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017311 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA017311: AB_1857415" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (5.33e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.26e-2)" "unprognostic (2.35e-2)" "unprognostic (7.39e-2)" "unprognostic (5.98e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.71e-2)" "unprognostic (3.04e-1)" "unprognostic (1.53e-2)" "unprognostic (1.13e-1)" 5.8 5.9 9.0 7.2 12.7 9.9 6.2 10.8 12.9 8.6 1.6 7.1 7.4 7.7 5.0 6.9 6.5 6.5 3.9 9.0 10.6 5.9 9.6 6.3 9.7 10.8 11.2 9.1 5.3 6.2 4.4 6.8 10.5 6.3 7.5 6.9 4.2 5.3 7.8 7.4 8.0 7.3 11.6 7.0 6.3 9.8 10.7 14.1 8.5 10.0 9.2 7.3 4.4 13.9 17.5 12.2 19.7 19.5 12.0 14.2 17.8 9.4 13.7 9.7 8.6 16.9 14.8 30.2 8.5 13.1 14.2 12.0 19.5 9.6 11.9 20.7 11.8 33.3 6.0 20.5 11.0 23.2 22.4 7.9 12.3 12.4 11.6 11.7 21.5 9.6 27.6 10.0 10.7 7.4 37.8 19.4 20.5 19.2 7.1 19.8 27.9 19.5 13.0 10.7 27.9 29.9 16.0 13.2 15.9 16.0 8.7 15.8 18.8 10.6 16.2 9.5 11.1 14.7 29.7 23.8 11.6 19.9 13.0 1.8 3.5 3.8 1.8 4.9 2.5 2.4 2.8 2.9 3.9 1.9 2.9 3.0 5.3 3.9 3.8 1.7 4.2 2.5 9.0 12.7 10.8 12.9 9.0 10.6 10.8 11.2 10.5 11.6 10.7 13.9 15.0 9.6 4.4 26.4 12.2 9.6 5.9 7.9 11.4 15.4 11.7 6.9 8.0 8.6 7.9 5.5 22.9 9.6 21.4 11.4 0.0 6.6 4.4 16.9 11.8 11.3 10.8 10.3 38.9 8.0 7.4 8.1 9.7 13.7 10.1 16.7 7.9 12.0 9.7 10.1 55.2 10.8 10.2 17.5 9.9 8.5 8.7 17.6 1.8 36.5 21.1 7.9 18.6 59.3 62.7 10.4 9.8 10.1 12.5 8.7 10.9 7.0 13.0 14.1 0.0 11.9 11.9 16.7 21.2 11.7 13.1 8.1 13.3 10.9 10.4 7.2 SLC30A6 "FLJ31101, ZNT6" ENSG00000152683 "Solute carrier family 30 member 6" Q6NXT4 2 32165841-32224379 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055032, HPA057328" Uncertain Enhanced "Golgi apparatus" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Golgi apparatus" "HPA055032: AB_2682677, HPA057328: AB_2683411" "unprognostic (5.61e-2)" "unprognostic (9.11e-3)" "unprognostic (1.05e-3)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.58e-6)" "unprognostic (2.98e-1)" "unprognostic (9.47e-2)" "unprognostic (1.88e-1)" "unprognostic (3.30e-3)" "unprognostic (7.05e-2)" "unprognostic (3.06e-2)" "unprognostic (3.51e-1)" "unprognostic (3.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" 10.3 8.9 4.0 8.5 4.8 4.2 10.1 5.2 4.8 10.1 5.1 10.0 8.6 9.2 7.5 8.8 8.0 9.0 7.6 4.0 4.5 11.7 11.2 8.4 9.8 5.0 4.4 9.0 10.4 11.3 4.3 12.1 4.9 8.8 10.0 6.0 7.7 7.8 7.8 8.0 8.4 9.4 4.8 7.8 9.2 6.2 4.4 9.4 11.8 7.6 10.3 9.9 5.6 6.2 27.7 20.3 20.5 18.0 25.4 22.6 22.7 25.3 25.0 20.4 18.5 15.8 25.4 13.1 16.4 20.4 23.4 17.0 24.7 17.4 25.8 26.6 13.7 28.6 10.9 20.3 16.3 30.4 16.9 17.0 26.7 27.4 21.8 20.7 16.6 9.2 24.6 17.2 23.6 10.2 16.1 13.9 31.0 30.8 10.6 14.2 24.7 19.3 22.5 23.9 15.3 23.3 19.9 21.2 20.4 19.0 11.7 13.6 14.3 25.9 14.3 17.2 30.3 23.1 43.5 19.2 23.0 23.4 26.6 12.8 2.4 1.9 2.5 2.0 3.5 3.0 2.3 2.8 2.9 2.7 3.4 3.2 2.4 7.0 2.3 2.0 4.6 2.0 4.0 4.8 5.2 4.8 4.0 4.5 5.0 4.4 4.9 4.8 4.4 6.2 8.6 9.6 9.9 19.9 14.9 9.1 5.3 14.9 13.6 4.5 9.0 5.7 4.1 8.6 8.3 7.3 6.2 19.8 8.4 9.5 5.9 7.5 2.8 7.4 10.1 10.9 3.6 13.2 29.2 8.7 14.7 9.5 11.7 10.5 3.8 12.9 11.4 15.3 10.7 1.7 31.0 7.9 14.2 8.8 9.3 1.0 6.5 6.6 8.8 10.3 7.7 7.5 12.3 27.2 37.2 9.8 7.0 7.9 20.0 8.7 9.1 8.3 10.0 7.1 13.1 7.3 7.3 12.3 9.4 13.6 6.3 27.5 9.5 9.0 9.0 5.2 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 129.1;choroid plexus: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" 7.0 6.2 69.9 5.5 66.9 2.5 8.4 69.6 129.1 6.1 65.6 6.9 5.8 6.9 7.2 5.0 5.0 4.5 7.4 71.7 68.8 7.7 9.2 5.6 5.9 69.3 67.7 6.6 14.8 6.5 5.2 5.9 71.9 6.6 6.2 13.1 7.4 5.6 8.0 7.0 5.8 6.5 66.8 6.9 6.4 4.2 67.3 7.9 10.1 6.0 5.1 5.3 5.1 75.4 8.9 4.4 8.6 7.7 9.8 12.4 4.5 7.5 7.5 7.7 5.0 5.9 6.6 4.7 5.1 8.2 7.4 6.8 9.2 6.6 10.0 7.6 14.3 7.6 9.8 10.7 11.5 10.2 6.2 8.7 12.4 6.9 11.0 10.6 6.6 5.2 10.7 9.6 8.5 5.8 8.0 10.6 7.0 9.6 7.5 5.5 12.7 8.9 8.4 3.8 9.6 9.2 6.4 6.4 11.7 5.5 3.5 8.6 7.4 10.1 4.8 7.1 7.2 14.2 19.1 5.8 15.9 9.7 5.7 14.9 5.4 5.7 4.4 5.1 3.7 4.6 4.4 4.1 4.6 4.0 4.5 4.0 14.9 6.4 5.1 5.4 4.6 4.7 69.9 66.9 69.6 129.1 71.7 68.8 69.3 67.7 71.9 66.8 67.3 75.4 61.4 93.0 69.8 13.1 68.5 51.4 56.9 59.5 50.7 113.8 63.3 28.2 88.0 60.1 58.3 42.3 106.3 68.4 81.3 68.8 33.2 45.3 34.7 39.5 57.9 59.0 57.1 86.9 18.8 39.3 69.9 66.6 28.1 40.1 40.0 56.3 67.8 80.9 48.3 101.0 20.1 70.2 50.8 81.7 60.7 21.0 86.6 58.0 81.8 21.5 85.1 53.1 114.4 22.1 31.8 41.8 66.8 74.9 62.6 78.5 62.7 60.1 62.2 122.2 78.9 71.9 66.2 160.2 59.6 41.1 65.9 192.8 60.7 65.4 46.8 74.7 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 TTC27 FLJ20272 ENSG00000018699 "Tetratricopeptide repeat domain 27" Q6P3X3 2 32628032-32821051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031246 Approved Approved Nucleoli,Mitochondria No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Mitochondria Nucleoli "HPA031246: AB_10603139" "unprognostic (3.10e-2)" "unprognostic (8.84e-2)" "unprognostic (3.21e-3)" "unprognostic (6.28e-3)" "unprognostic (8.90e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.42e-5)" "unprognostic (7.68e-2)" "unprognostic (2.30e-1)" "unprognostic (2.13e-1)" "unprognostic (2.07e-3)" "unprognostic (1.58e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.37e-1)" "unprognostic (2.96e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" 7.9 8.2 3.4 8.1 4.4 7.5 12.2 3.9 4.1 7.7 3.6 7.3 5.7 9.1 8.9 9.2 9.6 5.4 8.6 3.2 6.2 7.3 7.9 6.3 9.4 3.8 3.3 11.7 8.3 10.8 4.4 8.3 4.1 6.9 8.6 5.2 8.9 5.6 9.9 8.4 5.9 9.3 3.4 8.6 6.7 12.5 4.6 7.5 9.9 8.4 11.3 9.5 7.1 8.2 43.0 20.6 13.9 10.5 11.5 23.1 6.7 17.5 14.2 26.3 22.9 31.6 25.3 37.3 15.2 26.3 27.3 21.2 22.4 27.4 38.1 17.9 27.4 42.0 10.3 43.7 21.9 40.7 21.3 15.3 24.5 32.0 34.5 12.9 24.4 9.2 59.5 10.7 23.6 17.0 32.4 14.0 25.3 18.9 21.3 21.2 29.9 32.1 20.2 24.8 11.4 16.6 14.3 13.1 16.7 16.1 16.2 9.6 20.6 16.4 18.2 19.8 30.3 15.0 4.1 41.8 17.8 31.2 17.9 0.0 4.7 0.0 9.1 10.0 10.1 9.9 10.1 9.1 10.5 9.7 12.6 9.8 0.2 9.3 7.1 4.9 9.6 5.9 3.4 4.4 3.9 4.1 3.2 6.2 3.8 3.3 4.1 3.4 4.6 8.2 6.8 9.6 10.4 19.9 10.1 5.6 9.2 7.2 8.0 5.1 6.3 4.3 8.2 4.3 8.8 0.0 4.2 13.4 4.8 2.2 7.9 10.1 18.2 5.6 6.7 8.0 7.3 6.3 27.6 9.5 12.7 8.8 7.7 5.2 12.0 12.0 3.9 4.9 7.6 3.3 33.7 4.5 2.0 8.1 4.6 2.7 8.4 4.0 5.4 27.2 6.5 5.5 1.0 32.2 66.7 5.1 4.7 7.2 6.5 7.0 2.2 4.8 12.4 6.0 6.6 9.7 6.4 28.3 11.3 7.4 5.7 6.4 8.2 9.9 7.9 6.8 LTBP1 ENSG00000049323 "Latent transforming growth factor beta binding protein 1" Q14766 2 32946953-33399509 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 161.4" "Cell type enhanced" "Detected in many" "Astrocytes: 108.4;Fibroblasts: 116.1;Leydig cells: 90.4;Peritubular cells: 161.0;Skeletal myocytes: 85.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "ASC TERT1: 569.4;HSkMC: 185.3;HUVEC TERT2: 194.5;U-2197: 181.1;U-87 MG: 255.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" CAB025428 Approved "Secreted to extracellular matrix" NA NA 96000000 "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "CAB025428: " "unprognostic (1.02e-2)" "unprognostic (1.12e-1)" "unprognostic (5.29e-2)" "unprognostic (6.23e-2)" "unprognostic (3.11e-3)" "unprognostic (1.83e-1)" "unprognostic (1.06e-3)" "unprognostic (5.67e-2)" "unprognostic (7.48e-2)" "unprognostic (1.14e-1)" "unprognostic (9.96e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.79e-6)" "unprognostic (4.61e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (1.62e-4)" 22.9 13.1 7.8 22.1 9.4 11.5 14.5 7.1 7.5 161.4 10.5 27.2 10.2 58.9 37.8 21.2 37.0 73.0 89.0 8.8 9.1 38.6 18.6 27.5 6.9 12.1 10.6 30.2 7.9 2.4 9.0 73.2 9.2 46.9 16.5 0.7 14.6 73.6 15.7 10.8 15.0 96.7 9.1 8.3 32.8 17.9 8.8 8.2 6.5 28.4 18.7 53.9 28.3 13.4 0.3 12.5 31.3 0.3 26.1 569.4 13.5 46.5 95.7 6.4 9.3 25.3 4.6 41.3 1.0 6.0 8.8 2.4 0.7 1.5 22.0 0.6 15.3 135.6 15.0 4.1 118.6 0.5 15.7 185.3 4.4 141.2 6.9 61.8 194.5 6.3 8.7 0.3 51.1 19.9 5.5 0.2 22.4 1.0 39.2 4.7 65.8 0.6 0.4 22.4 6.3 3.4 9.5 72.1 0.8 49.1 27.9 0.4 126.4 6.4 26.2 181.1 37.6 74.8 80.0 58.8 255.9 5.2 10.8 3.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 5.3 7.8 9.4 7.1 7.5 8.8 9.1 12.1 10.6 9.2 9.1 8.8 13.4 33.6 0.0 0.6 108.4 0.4 13.5 5.6 13.0 10.2 0.0 6.9 6.6 80.9 4.3 3.6 1.8 0.0 45.2 0.3 12.9 0.0 9.6 6.3 7.3 18.3 28.1 1.2 30.3 30.4 6.5 23.4 116.1 10.2 10.5 0.0 11.8 20.3 11.0 7.6 0.0 54.3 2.8 2.0 0.3 18.1 7.1 90.4 12.0 19.6 39.4 0.4 0.2 0.0 70.4 52.4 19.1 3.3 161.0 1.3 19.1 0.7 0.3 6.3 0.3 59.2 85.8 67.9 0.7 11.9 6.9 9.8 43.5 2.0 2.6 4.1 33.4 RASGRP3 "CalDAG-GEFIII, GRP3, KIAA0846" ENSG00000152689 "RAS guanyl releasing protein 3" Q8IV61 2 33436324-33564750 "Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;skeletal muscle: 42.0" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 186.5;Plasma cells: 64.8;Urothelial cells: 106.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 13.9;memory B-cell: 12.3;naive B-cell: 15.2" "Group enriched" "Detected in many" 16 "B-cells: 15.2;granulocytes: 13.9" "Group enriched" "Detected in many" 7 "Daudi: 88.7;HEL: 92.0;U-266/70: 143.5;U-266/84: 59.1;U-698: 38.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058937 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Golgi apparatus" "HPA058937: AB_2683858" "unprognostic (2.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.45e-1)" "unprognostic (5.76e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (3.90e-1)" "unprognostic (7.57e-2)" "unprognostic (2.39e-2)" "unprognostic (4.35e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (9.96e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" 7.8 2.9 17.7 15.1 35.2 4.8 5.3 29.8 21.6 3.7 10.2 4.7 7.3 2.5 1.1 2.4 2.5 6.5 34.2 15.1 20.2 6.5 5.5 7.7 27.9 37.4 27.1 1.0 3.4 6.8 2.4 11.0 34.6 1.6 6.6 1.0 6.1 2.0 42.0 1.8 4.7 4.7 25.0 14.8 7.4 0.9 30.7 4.2 6.7 17.6 33.6 6.7 1.2 56.4 0.1 0.0 0.0 0.0 0.0 0.5 0.2 1.2 0.7 4.3 12.4 2.3 0.5 88.7 0.4 0.7 1.0 0.1 0.0 0.0 1.1 9.0 0.8 92.0 0.6 0.0 1.3 0.4 12.4 0.1 0.0 0.1 0.2 1.8 5.3 0.8 0.3 4.8 2.0 0.0 0.7 7.2 0.4 0.5 0.1 0.2 4.1 0.1 1.0 5.3 0.6 0.0 0.0 0.3 4.6 0.1 0.1 0.4 1.7 0.3 0.3 0.4 0.8 143.5 59.1 38.7 0.2 0.4 0.3 13.9 0.0 0.0 0.3 0.0 0.4 12.3 0.6 0.6 0.3 15.2 0.9 0.2 0.0 0.3 0.1 0.0 0.8 1.1 17.7 35.2 29.8 21.6 15.1 20.2 37.4 27.1 34.6 25.0 30.7 56.4 41.4 0.0 5.8 2.0 46.7 5.4 31.2 0.9 0.0 1.6 4.8 2.8 50.8 1.5 3.7 5.5 0.0 0.5 3.6 1.1 11.7 21.1 1.6 10.0 3.9 57.9 0.0 7.4 4.9 54.6 1.3 4.4 3.6 31.0 17.8 2.4 60.7 6.0 44.5 0.0 3.5 0.0 2.0 9.4 26.1 0.8 0.9 29.1 40.9 34.7 13.8 0.2 0.0 2.5 186.5 44.8 0.1 1.9 64.8 37.0 0.2 14.3 3.9 1.3 0.0 5.5 4.1 1.4 2.1 0.4 3.7 0.5 8.1 3.8 0.4 106.4 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 CRIM1 S52 ENSG00000150938 "Cysteine rich transmembrane BMP regulator 1" Q9NZV1 2 36355778-36551135 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 163.8" "Cell type enhanced" "Detected in many" "Adipocytes: 262.9;Hepatic stellate cells: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 466.5;fHDF/TERT166: 462.5;TIME: 651.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000556 Enhanced "Intracellular and membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "HPA000556: AB_1078567" "unprognostic (2.15e-1)" "unprognostic (5.41e-2)" "unprognostic (6.39e-2)" "unprognostic (3.17e-3)" "unprognostic (3.88e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (4.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.51e-4)" "unprognostic (1.98e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (6.67e-2)" 88.3 14.6 27.0 18.8 28.1 3.5 58.9 9.4 23.5 26.7 51.4 28.7 14.9 26.6 16.7 30.5 34.4 32.2 34.5 20.3 28.8 70.0 16.0 50.1 14.8 23.5 21.9 36.9 23.5 29.2 7.4 163.8 21.2 25.8 23.2 29.5 31.1 32.6 50.1 27.2 18.2 35.7 22.1 47.1 17.5 12.4 36.1 9.9 33.8 36.5 8.7 38.9 22.2 17.1 100.9 75.4 15.2 17.5 69.1 78.0 125.0 466.5 244.7 255.4 133.4 95.3 34.2 0.2 297.9 462.5 166.1 42.8 11.4 75.2 206.5 1.1 8.7 3.2 96.7 55.5 221.5 2.2 0.6 110.1 55.2 102.4 182.4 238.4 361.9 1.9 4.7 0.7 271.6 9.2 0.2 1.2 11.9 5.2 22.1 5.4 19.6 15.5 159.8 41.1 1.8 0.2 81.5 26.4 3.4 56.2 72.3 2.0 651.1 321.7 116.1 40.4 229.1 25.5 0.5 0.9 94.7 0.4 100.8 1.4 0.1 0.5 0.6 0.0 0.4 0.3 0.2 0.3 0.1 0.2 0.0 0.3 0.2 0.4 0.6 2.1 0.2 0.0 27.0 28.1 9.4 23.5 20.3 28.8 23.5 21.9 21.2 22.1 36.1 17.1 262.9 12.8 43.3 100.2 5.4 66.0 38.5 30.1 43.9 12.0 55.6 72.9 34.4 47.1 26.5 132.4 2.1 111.9 27.1 49.5 3.9 33.5 1.0 37.1 27.7 159.8 31.8 10.7 85.1 2.6 40.6 41.0 10.2 75.9 1.3 27.4 207.1 3.6 27.7 0.0 57.5 37.7 36.7 7.7 32.5 2.0 19.0 8.2 39.2 135.9 7.1 18.5 6.2 65.9 17.2 26.5 30.9 19.9 6.9 75.5 11.5 38.4 28.9 42.5 46.0 18.4 164.6 2.1 9.4 22.0 30.1 173.5 17.1 5.7 33.2 58.3 FEZ2 ENSG00000171055 "Fasciculation and elongation protein zeta 2" Q9UHY8 2 36531805-36646087 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035978 Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoli, Nucleoli rim" "Golgi apparatus, Cytosol" "HPA035978: AB_10672235" "unprognostic (1.42e-1)" "unprognostic (5.02e-3)" "unprognostic (2.89e-1)" "unprognostic (1.15e-2)" "unprognostic (2.91e-2)" "unprognostic (1.94e-3)" "prognostic unfavorable (7.79e-6)" "unprognostic (1.09e-1)" "unprognostic (7.05e-2)" "unprognostic (2.42e-1)" "unprognostic (1.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.65e-2)" "unprognostic (7.82e-3)" "unprognostic (7.07e-2)" "unprognostic (3.47e-2)" "unprognostic (1.82e-1)" 53.0 39.1 48.2 21.0 51.6 16.5 35.9 48.2 68.6 26.9 42.8 34.5 22.1 33.1 18.9 31.7 23.8 23.6 46.7 49.2 48.4 33.6 29.4 27.1 24.3 49.5 46.3 27.6 10.8 20.3 14.2 46.8 48.2 23.5 27.9 26.5 17.1 32.5 108.1 17.0 28.5 41.1 50.1 30.3 21.9 20.8 49.6 18.2 23.9 78.5 19.5 29.1 24.3 56.3 64.9 37.1 49.4 22.3 91.3 122.1 39.5 157.1 76.5 90.7 56.0 24.6 21.5 39.1 94.7 199.2 41.0 25.1 42.4 54.3 98.5 9.3 24.7 31.7 12.2 43.5 44.4 32.9 8.5 119.9 44.2 57.8 69.6 61.2 131.0 9.5 35.4 12.0 170.2 22.7 19.6 27.5 27.1 33.9 57.8 16.9 44.3 14.0 72.9 57.6 1.9 45.7 38.7 31.9 37.8 51.7 11.3 39.1 161.2 59.7 32.9 33.4 92.9 9.8 11.5 26.6 58.9 22.4 84.8 2.5 3.5 5.1 1.7 3.4 1.0 1.6 1.3 1.0 3.5 1.0 1.5 0.7 4.2 3.2 2.3 15.6 1.4 0.8 48.2 51.6 48.2 68.6 49.2 48.4 49.5 46.3 48.2 50.1 49.6 56.3 109.4 54.5 37.5 25.8 23.7 31.4 94.7 45.5 41.5 52.5 31.7 33.1 43.1 17.2 70.2 58.8 45.9 96.4 61.1 57.6 56.7 80.3 5.6 38.4 44.7 100.9 24.0 15.3 45.4 30.6 87.6 50.7 27.0 64.3 24.1 66.0 97.5 37.2 93.7 21.9 22.9 28.8 38.7 88.1 65.4 10.7 54.3 64.6 56.9 45.0 56.0 97.1 35.0 23.1 50.5 74.4 41.4 66.2 17.9 99.1 65.6 45.1 35.9 36.3 59.2 64.0 51.2 12.1 34.9 24.0 32.1 180.1 24.2 47.2 37.7 140.6 VIT ENSG00000205221 Vitrin Q6UXI7 2 36696690-36814792 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 35.4;tongue: 41.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 68.3;Fibroblasts: 58.8;Granulosa cells: 45.1;Leydig cells: 115.2;Skeletal myocytes: 45.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3;naive CD8 T-cell: 1.3" "Lineage enriched" "Detected in single" 10 "T-cells: 2.3" "Cell line enhanced" "Detected in some" "ASC diff: 33.6;ASC TERT1: 65.2;BJ: 32.9;fHDF/TERT166: 112.3;SuSa: 62.2;THP-1: 35.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (5.34e-4)" "unprognostic (4.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.20e-1)" "unprognostic (7.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.81e-1)" "unprognostic (3.08e-1)" "unprognostic (3.35e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" "unprognostic (3.66e-6)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (3.62e-3)" "unprognostic (1.41e-2)" 35.4 0.9 0.2 0.5 0.5 0.9 15.4 0.8 0.9 6.0 0.4 3.9 0.4 1.0 0.6 8.7 7.9 2.3 18.6 0.3 0.1 0.2 0.0 1.2 2.3 0.1 0.1 28.7 1.0 0.6 3.1 2.2 0.1 7.0 1.5 0.0 11.6 2.3 12.5 12.7 2.7 0.2 0.0 0.1 4.7 3.0 0.3 1.0 8.9 41.1 2.2 15.0 14.6 0.2 0.0 0.0 0.0 0.0 33.6 65.2 0.0 32.9 7.7 10.4 4.3 0.0 0.0 0.0 0.0 112.3 0.1 0.2 6.2 0.0 6.9 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.3 1.6 0.0 0.0 0.0 2.5 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.7 0.0 62.2 0.0 35.6 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 2.5 2.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.5 0.8 0.9 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.2 4.1 0.0 0.0 0.7 0.0 4.2 0.9 0.0 68.3 0.0 0.2 10.0 3.2 0.0 0.0 0.0 0.0 10.6 0.9 0.3 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.0 1.8 0.0 11.0 58.8 0.0 0.0 0.0 45.1 0.4 0.0 1.1 0.0 0.7 0.4 0.0 0.0 3.5 2.7 115.2 0.5 7.2 20.6 0.0 0.0 4.1 0.5 0.3 0.0 0.1 23.3 0.8 0.1 0.0 0.0 0.0 0.0 6.6 45.2 6.1 1.1 0.6 1.6 3.4 4.2 1.1 0.1 0.3 0.2 STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 294.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Nucleoplasm "HPA017286: AB_1857618" "unprognostic (1.65e-1)" "unprognostic (1.65e-1)" "unprognostic (3.57e-3)" "unprognostic (2.23e-2)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.63e-3)" "unprognostic (7.37e-2)" "unprognostic (1.25e-1)" "unprognostic (2.42e-1)" "unprognostic (1.77e-3)" "unprognostic (1.33e-1)" "prognostic favorable (2.27e-4)" "unprognostic (1.13e-1)" "unprognostic (6.43e-2)" "unprognostic (2.11e-1)" "unprognostic (3.43e-2)" 8.4 4.7 5.3 9.4 16.7 14.9 8.6 11.9 9.0 8.6 0.6 9.1 8.1 6.2 3.8 21.2 5.3 6.8 21.2 5.5 10.2 8.4 7.5 7.8 7.7 13.0 11.6 7.7 5.6 7.3 2.4 10.1 13.1 5.5 10.7 10.1 10.7 5.0 11.6 11.2 8.6 7.7 9.8 8.1 9.0 8.0 14.2 13.3 6.2 11.5 12.6 8.4 10.1 24.7 38.3 19.0 25.2 10.4 13.3 18.0 24.6 14.8 14.2 14.5 13.3 19.4 12.2 24.7 11.8 19.7 20.6 17.6 21.4 17.0 17.9 27.9 16.0 40.2 16.4 10.3 12.1 24.9 21.8 11.4 12.9 23.2 18.3 10.7 18.6 10.0 30.4 19.2 18.2 11.1 24.7 7.4 19.8 15.7 9.4 15.9 38.5 11.2 9.7 31.0 4.5 15.1 22.4 16.9 13.6 13.7 12.2 9.2 24.9 25.4 25.4 16.0 20.1 19.5 31.0 21.6 13.2 23.2 18.2 1.3 0.2 0.4 0.5 0.4 0.2 0.4 0.4 0.3 0.1 0.2 0.2 0.2 1.0 0.2 0.4 0.2 0.1 0.1 5.3 16.7 11.9 9.0 5.5 10.2 13.0 11.6 13.1 9.8 14.2 24.7 26.5 9.6 10.0 38.8 18.8 20.6 12.3 11.3 21.6 12.7 16.0 9.4 55.4 8.6 17.4 23.9 20.9 8.0 22.8 25.0 9.8 10.5 1.9 14.2 14.3 19.4 11.4 26.5 65.3 8.4 10.3 13.6 20.4 26.2 5.1 16.0 16.4 7.9 8.8 18.5 55.2 17.8 10.2 20.7 10.0 2.1 9.6 18.0 8.8 47.8 20.3 10.1 35.0 55.3 294.0 16.8 14.1 12.4 14.3 19.3 13.0 8.5 8.2 16.9 0.0 13.6 16.5 15.2 19.2 31.4 33.2 16.3 19.4 17.7 16.0 39.4 HEATR5B "DKFZp686P15184, KIAA1414" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.3;Inhibitory neurons: 58.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042025, HPA055639" Approved Approved "Nuclear speckles,Vesicles,Cytosol" NA NA 6800 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Vesicles, Cytosol" "HPA042025: AB_10959880, HPA055639: AB_2682870" "unprognostic (3.11e-2)" "unprognostic (1.65e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.66e-1)" "unprognostic (8.07e-2)" "unprognostic (5.80e-3)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.95e-1)" 9.7 8.8 7.1 15.0 7.1 24.3 14.5 11.7 9.8 9.9 4.9 9.9 10.8 9.5 16.9 11.7 8.1 10.7 9.7 7.4 6.4 9.3 9.3 10.8 31.9 5.8 5.2 9.8 18.2 13.4 6.3 10.2 6.4 11.4 13.5 24.3 14.3 7.7 4.9 18.2 11.5 8.3 3.9 19.0 12.3 9.6 7.0 24.7 11.8 9.4 31.2 10.1 8.5 8.1 16.2 8.1 11.7 17.8 11.9 11.7 14.9 10.1 7.4 9.0 9.1 9.6 10.9 34.6 7.1 8.6 11.9 13.4 11.6 8.2 11.7 17.0 12.6 22.6 11.3 13.1 7.4 24.5 28.5 10.8 11.2 13.0 12.3 9.9 15.5 18.3 21.6 29.8 10.9 9.6 21.5 17.4 7.7 16.7 5.6 20.5 11.9 26.3 10.5 13.8 14.3 12.6 10.6 16.7 7.8 11.7 12.0 7.9 17.2 13.5 7.7 9.9 7.9 18.5 16.2 39.0 11.0 14.3 9.0 18.3 5.0 12.3 7.7 2.8 7.1 9.7 8.5 8.7 9.0 14.0 8.7 7.6 5.2 7.5 4.4 11.2 9.7 5.9 7.1 7.1 11.7 9.8 7.4 6.4 5.8 5.2 6.4 3.9 7.0 8.1 12.9 22.4 10.3 35.9 20.8 9.8 4.2 4.7 6.8 13.0 11.9 8.3 20.8 8.6 7.1 5.5 10.4 7.0 24.4 11.3 1.9 4.6 6.3 14.8 10.0 9.5 5.4 18.7 62.3 6.2 6.2 9.4 25.5 11.1 7.0 9.8 11.7 7.8 6.3 16.8 58.9 8.9 6.1 17.0 15.7 2.6 9.0 13.2 7.2 56.2 9.2 6.5 16.5 57.3 69.7 8.8 6.3 6.4 17.6 5.5 12.7 5.4 12.8 16.2 19.7 6.5 10.6 3.6 11.2 11.7 11.6 5.6 14.5 7.7 8.7 4.9 GPATCH11 "CCDC75, CENP-Y, CENPY, FLJ38348" ENSG00000152133 "G-patch domain containing 11" Q8N954 2 37084451-37099244 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038231, HPA038232" Enhanced Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA038231: AB_2675904, HPA038232: AB_10675788" "unprognostic (1.28e-2)" "unprognostic (1.58e-1)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (3.88e-2)" "unprognostic (2.23e-2)" "unprognostic (4.58e-3)" "unprognostic (2.40e-2)" "unprognostic (2.44e-2)" "unprognostic (4.39e-2)" "unprognostic (1.16e-1)" "unprognostic (1.26e-1)" "unprognostic (8.64e-3)" "unprognostic (4.31e-2)" "unprognostic (4.44e-2)" "unprognostic (3.40e-2)" "unprognostic (7.16e-2)" 23.0 6.3 7.5 7.8 8.5 10.0 6.9 8.8 9.9 7.0 6.0 4.5 4.8 4.8 3.7 5.1 3.7 4.4 5.4 7.7 8.8 5.5 5.7 6.3 12.7 8.3 8.0 5.9 3.0 5.5 3.5 5.7 8.5 4.0 4.9 21.0 3.7 4.1 2.4 5.9 5.0 4.3 8.5 8.0 4.8 11.6 8.0 10.3 6.4 5.4 11.7 5.2 3.1 10.4 12.5 7.4 12.4 9.7 25.7 11.9 13.2 22.1 8.9 13.1 10.7 9.4 5.2 14.4 12.1 8.3 11.4 8.8 14.8 5.3 19.5 24.7 16.1 26.3 9.8 9.6 8.3 31.7 27.5 7.8 9.4 18.0 10.1 8.6 11.6 9.0 25.0 65.8 15.4 6.3 20.6 17.4 5.3 20.5 10.3 16.9 26.4 40.7 5.7 5.3 14.9 13.9 11.6 7.4 11.2 9.9 7.6 14.6 12.9 23.7 13.1 17.4 24.7 25.6 28.2 21.6 16.9 26.2 21.3 5.9 2.4 2.2 4.4 2.0 4.4 8.7 3.2 3.7 3.6 6.8 3.4 3.5 0.8 6.7 0.7 12.2 2.6 1.5 7.5 8.5 8.8 9.9 7.7 8.8 8.3 8.0 8.5 8.5 8.0 10.4 14.7 12.8 8.1 3.9 23.3 4.2 2.7 5.7 7.4 24.3 6.2 7.0 14.1 8.6 5.0 11.0 25.0 8.8 48.7 12.1 11.7 9.3 32.9 12.6 20.0 12.8 3.0 22.1 14.3 14.1 30.5 12.2 8.6 13.9 12.0 8.7 17.9 15.0 13.4 13.5 12.1 9.1 6.1 18.8 15.0 10.5 16.1 21.1 3.6 5.6 12.7 28.9 22.6 10.6 12.5 14.8 4.9 22.2 23.2 1.6 9.7 13.2 11.5 52.7 13.1 13.4 21.7 75.5 43.6 7.8 5.4 3.8 16.8 13.7 6.0 2.0 EIF2AK2 "EIF2AK1, PKR, PPP1R83, PRKR" ENSG00000055332 "Eukaryotic translation initiation factor 2 alpha kinase 2" P19525 2 37099210-37157522 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003845, HPA019795, HPA063893" Approved Enhanced Cytosol NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB003845: AB_562332, HPA019795: AB_1848060, HPA063893: AB_2685144" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.77e-3)" "unprognostic (8.42e-2)" "unprognostic (8.02e-2)" "unprognostic (4.67e-2)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.19e-1)" "unprognostic (3.15e-3)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (4.65e-2)" "unprognostic (5.32e-2)" 11.1 9.0 7.2 10.5 8.1 30.1 8.6 7.4 9.5 9.8 8.6 8.8 7.6 10.5 8.0 6.3 8.3 9.5 6.3 7.8 11.1 8.5 7.7 8.9 8.0 10.9 8.1 10.8 7.4 11.1 6.6 11.2 10.9 10.1 8.6 6.6 17.7 8.4 4.5 4.6 9.9 11.1 15.6 11.9 9.5 3.3 13.0 11.7 10.0 5.8 7.1 8.0 5.9 8.7 38.4 22.1 16.7 17.4 21.5 28.3 20.1 21.2 29.1 56.3 41.1 23.0 23.2 27.4 27.0 29.8 66.2 27.4 24.2 27.1 29.5 45.7 12.0 33.8 19.2 18.7 17.9 32.2 0.2 22.5 13.1 23.7 19.3 17.7 18.0 10.7 19.1 23.6 20.3 13.4 35.5 17.0 15.8 8.4 10.8 27.6 40.9 12.1 15.3 18.7 14.1 20.4 32.0 24.0 50.7 12.7 9.2 9.0 31.4 25.7 24.9 15.1 36.2 19.0 30.8 0.3 15.9 20.0 23.1 10.7 5.3 6.3 5.4 7.9 5.2 5.3 4.5 5.2 4.8 4.2 3.0 4.3 15.7 6.5 8.0 3.1 6.5 2.1 7.2 8.1 7.4 9.5 7.8 11.1 10.9 8.1 10.9 15.6 13.0 8.7 94.5 67.3 34.0 25.1 35.9 19.5 42.3 33.0 31.3 38.8 26.6 26.0 29.9 32.9 46.0 22.0 14.6 47.8 44.8 32.2 21.5 40.2 2.4 55.8 68.7 76.3 15.0 36.0 39.6 48.5 89.2 52.6 22.4 41.7 41.1 93.5 33.5 21.9 38.2 47.1 42.9 24.0 16.2 29.9 20.8 4.2 57.2 50.7 21.4 48.7 47.1 50.9 45.3 51.3 16.8 54.7 21.8 84.2 46.0 39.5 33.6 33.0 48.9 24.8 39.5 60.5 45.9 2.4 5.5 22.5 10.1 40.8 40.0 61.3 28.6 40.5 SULT6B1 ENSG00000138068 "Sulfotransferase family 6B member 1" Q6IMI4 2 37167820-37196598 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.6;testis: 2.4" "Group enriched" "Detected in some" 8 "Early spermatids: 3.5;Late spermatids: 1.8;Spermatocytes: 2.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "WM-115: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.86e-1)" "unprognostic (8.98e-2)" 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.6 0.3 0.1 0.2 0.4 0.3 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CEBPZOS CEBPZ-AS1 ENSG00000218739 "CEBPZ opposite strand" A8MTT3 2 37196488-37216193 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053866 Uncertain Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA053866: AB_2682283" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" "unprognostic (8.05e-3)" "prognostic unfavorable (1.72e-6)" "unprognostic (2.34e-2)" "unprognostic (2.40e-2)" "unprognostic (5.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (3.46e-7)" "unprognostic (3.69e-2)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (1.33e-2)" 22.3 46.5 23.6 15.0 24.7 25.4 22.4 26.4 32.7 23.9 25.6 28.8 23.8 23.4 38.5 24.3 23.9 17.7 42.5 26.4 24.9 35.9 27.9 17.8 22.7 24.7 24.0 28.3 22.9 24.9 31.1 22.0 24.8 29.9 22.6 28.1 26.1 18.2 53.4 23.9 22.5 20.2 23.1 20.6 24.5 22.7 24.5 18.3 26.0 37.3 19.6 24.0 22.0 27.9 59.9 19.4 41.1 32.9 42.5 47.0 39.4 43.2 39.3 27.2 19.8 18.5 26.4 20.7 22.9 42.8 36.2 33.7 22.4 32.9 33.4 55.3 47.1 56.2 21.6 29.0 38.2 70.5 29.4 49.6 44.0 37.1 42.1 36.7 44.3 21.4 42.6 28.9 45.3 11.9 17.2 67.6 60.2 47.6 29.5 51.4 55.8 47.2 48.6 15.9 43.4 42.6 33.4 54.0 43.5 22.1 23.9 41.2 39.0 29.1 35.9 43.2 38.1 53.0 0.5 44.1 54.0 41.2 42.5 32.4 23.0 21.2 27.3 26.4 32.2 34.1 31.1 29.2 22.8 26.9 38.5 34.9 8.8 23.2 20.6 49.2 23.5 22.3 23.6 24.7 26.4 32.7 26.4 24.9 24.7 24.0 24.8 23.1 24.5 27.9 46.6 54.5 40.9 13.7 37.7 0.0 51.6 0.0 51.2 46.5 37.6 38.9 43.0 27.1 21.1 38.6 18.8 83.0 43.6 25.7 92.0 46.8 76.0 59.1 35.7 27.9 17.5 30.1 14.7 33.7 50.7 35.6 41.3 41.4 17.1 30.3 27.5 27.4 44.5 32.0 19.5 32.6 0.0 27.7 0.0 18.2 47.2 34.7 0.0 18.7 39.9 59.8 46.4 13.6 27.1 41.8 31.0 44.4 30.4 38.9 54.2 92.1 27.0 56.2 46.0 31.0 33.0 115.8 58.8 48.5 0.0 69.1 37.8 33.4 33.1 41.6 CEBPZ "CBF2, CTF2" ENSG00000115816 "CCAAT enhancer binding protein zeta" Q03701 2 37201612-37231596 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 282.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052065 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA052065: AB_2681715" "unprognostic (1.64e-2)" "unprognostic (1.20e-1)" "unprognostic (3.00e-3)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.88e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (8.84e-2)" "unprognostic (3.85e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.13e-4)" "unprognostic (2.65e-2)" "unprognostic (5.36e-2)" "unprognostic (4.19e-2)" "unprognostic (8.76e-2)" "unprognostic (2.05e-1)" "unprognostic (8.01e-2)" 21.1 27.8 10.3 18.9 11.5 31.3 26.2 15.8 12.8 17.9 11.9 19.5 17.4 20.1 19.9 20.5 17.2 16.7 15.3 9.8 11.8 25.3 27.1 19.3 24.6 10.9 11.0 23.9 20.6 22.3 10.2 23.0 11.4 19.7 20.0 24.4 16.3 15.6 36.3 17.9 18.1 16.9 10.8 19.9 17.4 38.4 11.1 24.0 22.4 24.4 24.4 26.6 12.6 14.2 61.2 46.6 46.9 26.1 45.2 48.6 39.9 57.0 39.2 47.2 50.5 74.5 45.1 111.5 49.4 33.8 64.4 51.0 122.8 58.5 60.2 71.8 53.9 104.0 47.5 60.9 35.8 105.7 44.9 37.3 56.4 62.8 63.4 31.1 43.3 27.8 114.8 49.8 48.6 31.8 61.5 82.4 153.3 81.0 43.2 48.6 76.3 84.3 45.3 56.9 49.9 80.7 47.5 57.6 65.5 67.6 41.8 45.9 35.5 45.8 52.3 41.3 79.1 55.5 62.0 88.1 40.8 95.6 51.2 34.8 16.8 16.3 23.8 21.7 30.0 29.6 24.7 23.4 17.6 30.0 31.1 26.1 6.1 26.1 22.3 25.6 21.4 14.6 10.3 11.5 15.8 12.8 9.8 11.8 10.9 11.0 11.4 10.8 11.1 14.2 73.4 86.6 82.9 15.0 91.6 107.1 109.2 64.4 83.1 45.5 50.4 54.1 34.4 47.1 81.9 49.7 43.8 54.7 93.4 36.7 107.6 56.1 282.1 56.0 87.2 60.5 44.2 66.7 15.6 62.5 37.4 67.4 52.5 67.5 73.4 44.7 43.9 76.4 35.1 43.7 19.3 56.6 44.7 37.0 36.1 43.3 60.9 44.6 21.4 15.0 54.1 57.1 63.8 18.6 21.4 54.9 30.2 50.8 67.7 79.0 30.2 89.1 54.2 95.5 52.6 94.3 68.3 186.7 99.3 56.8 101.2 45.0 87.7 62.1 64.2 80.9 NDUFAF7 "C2orf56, MidA, PRO1853" ENSG00000003509 "NADH:ubiquinone oxidoreductase complex assembly factor 7" Q7L592 2 37231631-37253403 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.8" "Group enriched" "Detected in all" 4 "Early spermatids: 196.6;Late spermatids: 109.6;Spermatocytes: 118.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045217 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 43: Testis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045217: AB_10960395" "unprognostic (6.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.13e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (3.08e-4)" "unprognostic (5.44e-2)" "unprognostic (1.55e-2)" "unprognostic (9.88e-2)" "unprognostic (8.12e-3)" "unprognostic (5.94e-2)" "unprognostic (3.48e-2)" "unprognostic (1.03e-1)" "unprognostic (5.73e-2)" "unprognostic (8.67e-3)" 6.2 12.7 6.7 5.4 7.1 6.0 6.0 7.7 7.8 8.0 6.2 12.1 4.6 7.8 8.0 5.6 6.0 5.9 15.5 7.3 6.6 9.3 10.6 5.5 6.9 6.5 6.5 7.0 5.7 8.2 6.8 5.9 6.8 6.6 5.9 10.0 5.7 5.4 20.4 4.9 5.7 7.3 5.8 6.6 6.2 38.8 6.2 8.2 5.1 24.4 5.9 6.7 6.1 7.1 20.2 10.6 13.2 11.6 8.3 17.6 7.3 6.6 10.5 11.1 14.1 22.9 8.5 17.1 8.1 6.0 18.9 14.8 16.2 8.3 13.1 11.9 12.1 12.6 13.1 21.1 10.2 12.6 6.1 13.8 13.6 9.1 5.6 11.8 17.4 6.4 15.5 11.1 6.7 7.4 12.6 13.5 17.3 15.9 9.5 11.3 10.2 14.4 15.4 7.4 13.7 11.0 8.2 13.9 14.3 18.6 8.4 4.9 3.4 9.2 12.3 11.6 12.1 9.7 6.0 19.8 13.4 16.9 7.9 3.0 4.3 2.6 4.1 3.7 1.8 4.7 3.6 3.5 5.3 4.1 3.5 3.1 2.7 4.1 2.7 4.2 4.6 2.0 6.7 7.1 7.7 7.8 7.3 6.6 6.5 6.5 6.8 5.8 6.2 7.1 10.9 9.6 10.0 12.7 15.5 4.8 9.5 12.3 11.4 18.1 6.4 5.6 13.4 2.8 8.4 11.0 22.9 15.0 16.1 3.7 17.6 10.5 196.6 6.6 12.1 9.4 2.4 6.5 30.5 6.3 10.8 9.7 8.6 7.2 7.6 11.9 7.5 5.6 9.4 11.8 26.9 5.5 12.2 7.3 7.8 109.6 13.4 9.4 3.6 15.0 10.5 7.6 10.3 13.6 15.4 8.8 2.0 16.6 9.3 5.9 7.7 14.8 11.3 21.8 6.6 10.1 18.0 118.4 14.4 7.4 4.0 11.5 13.6 16.1 6.2 6.3 PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324833 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 152.1;U-266/84: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029529 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA029529: AB_10602082" "unprognostic (1.39e-1)" "unprognostic (7.34e-2)" "prognostic favorable (4.84e-4)" "unprognostic (1.23e-2)" "unprognostic (5.61e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.81e-1)" "unprognostic (7.62e-3)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.35e-1)" 15.1 19.9 6.1 18.1 6.8 8.7 14.4 7.8 7.3 19.3 3.9 16.4 8.2 18.9 13.8 10.7 9.9 13.3 9.8 6.0 7.5 12.0 10.1 14.7 29.1 7.2 7.1 18.0 9.1 11.7 6.5 14.9 7.8 11.7 11.0 41.6 10.5 12.5 14.9 12.2 10.3 16.2 7.6 23.4 12.4 23.3 8.1 20.7 13.4 12.1 28.9 15.5 9.5 7.1 38.8 14.3 44.4 36.1 33.2 55.1 31.5 25.0 48.8 29.1 28.7 23.4 14.0 58.5 20.1 39.6 43.2 15.0 31.1 31.9 39.0 72.3 38.7 39.2 24.4 17.8 13.8 26.2 21.5 26.0 16.2 46.2 29.7 26.6 52.6 19.9 32.3 70.9 33.8 6.1 11.6 21.6 45.4 0.4 14.2 40.8 67.9 51.8 18.9 42.1 32.5 81.0 24.6 13.9 152.1 22.8 15.1 25.1 47.7 80.0 40.5 31.5 28.5 78.1 159.7 68.2 27.8 11.2 48.7 6.9 7.7 6.1 9.5 6.7 8.1 10.6 8.5 8.1 7.7 14.6 9.6 10.8 1.4 6.9 3.6 8.1 4.4 3.6 6.1 6.8 7.8 7.3 6.0 7.5 7.2 7.1 7.8 7.6 8.1 7.1 41.4 41.7 17.8 21.9 60.2 37.9 32.1 24.1 14.8 47.6 14.7 15.5 9.1 27.1 16.6 18.4 68.8 11.2 37.7 7.3 3.9 13.1 57.1 8.3 38.5 48.0 18.8 12.0 24.8 10.6 37.0 33.0 20.4 14.1 76.9 26.8 44.3 12.2 12.8 43.7 18.7 6.9 22.4 31.2 91.2 100.6 33.5 24.4 49.8 68.4 32.7 15.9 27.8 37.7 12.6 16.1 4.3 30.9 60.2 34.3 6.6 8.6 10.3 118.8 26.3 27.5 24.0 54.7 39.9 10.6 23.9 9.7 33.5 29.1 12.3 34.1 QPCT "GCT, QC" ENSG00000115828 "Glutaminyl-peptide cyclotransferase" Q16769 2 37342827-37373322 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 170.3;epididymis: 104.0" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 217.0;Ionocytes: 138.4;Langerhans cells: 163.4;Melanocytes: 528.3" "Cancer enhanced" "Detected in all" "melanoma: 97.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 1527.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 1527.7" "Cell line enhanced" "Detected in many" "SCLC-21H: 117.1;SK-MEL-30: 426.8;U-266/84: 341.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008406 Enhanced Approved Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA008406: AB_1855981" "unprognostic (6.25e-3)" "unprognostic (6.69e-2)" "unprognostic (4.95e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-2)" "unprognostic (9.32e-2)" "unprognostic (1.13e-3)" "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "unprognostic (3.67e-2)" "unprognostic (1.17e-1)" "unprognostic (6.78e-2)" "unprognostic (7.76e-3)" "unprognostic (1.21e-1)" "unprognostic (9.48e-3)" "unprognostic (3.62e-3)" 5.6 170.3 8.4 14.2 7.5 47.3 15.8 5.1 11.5 21.2 4.2 25.3 5.6 9.8 104.0 3.4 2.2 10.8 5.1 8.9 27.4 6.1 2.6 5.6 8.1 9.7 11.6 1.0 13.7 14.8 27.0 9.2 14.7 7.2 10.2 11.9 25.5 6.7 4.1 36.3 4.5 8.3 7.8 13.9 7.6 2.0 20.3 5.1 3.8 2.8 12.5 15.2 4.6 6.7 1.0 40.7 0.1 0.0 6.0 13.3 0.1 6.6 86.5 6.4 10.1 2.9 7.1 0.2 3.0 32.6 72.9 0.1 2.7 0.6 10.3 0.6 76.0 18.7 0.3 7.7 0.6 3.0 0.1 8.5 0.0 47.3 0.2 0.4 26.2 0.0 0.0 0.0 0.2 4.5 0.0 1.7 0.6 0.3 0.0 0.0 0.0 0.8 42.6 10.9 117.1 0.2 6.4 1.4 426.8 8.0 0.7 2.9 19.4 0.0 0.2 0.1 0.6 15.3 341.7 0.3 25.8 0.3 0.0 9.8 344.8 3.2 0.4 38.7 1.0 2.6 0.6 0.5 124.7 1.2 0.5 0.3 1527.7 0.2 3.3 2.4 0.1 169.8 8.4 7.5 5.1 11.5 8.9 27.4 9.7 11.6 14.7 7.8 20.3 6.7 1.8 3.2 2.3 0.3 12.5 39.0 13.6 40.0 2.2 21.8 7.9 8.5 1.1 1.5 17.7 22.0 2.1 0.7 0.8 6.1 1.9 45.4 0.6 2.6 24.7 17.5 217.0 1.7 8.5 2.4 6.1 26.7 3.1 4.0 55.3 1.6 22.5 0.3 20.5 43.7 7.3 6.6 138.4 21.2 163.4 2.9 3.1 26.8 528.3 6.5 64.3 0.8 3.1 3.0 1.3 31.8 1.8 23.7 26.0 9.1 0.2 11.7 4.3 3.2 13.1 0.6 6.6 1.7 0.7 0.6 14.5 4.7 5.6 5.0 7.3 5.8 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 42.5" "Group enriched" "Detected in many" 4 "Early spermatids: 270.4;Late spermatids: 163.5;Theca cells: 77.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: AB_2674292, HPA034706: AB_10696362" "unprognostic (1.34e-1)" "unprognostic (2.61e-1)" "unprognostic (4.03e-2)" "unprognostic (1.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.76e-1)" "unprognostic (3.06e-2)" "prognostic favorable (2.63e-4)" "unprognostic (7.85e-2)" "unprognostic (9.96e-2)" "unprognostic (7.50e-2)" "unprognostic (1.94e-1)" "unprognostic (2.88e-2)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "unprognostic (4.34e-3)" "unprognostic (3.34e-1)" 4.6 42.5 3.8 4.1 3.5 3.4 5.3 4.8 4.5 7.7 2.9 12.4 8.4 5.1 9.2 3.4 3.9 6.2 4.4 4.1 2.6 7.8 29.2 11.3 4.6 3.9 2.6 2.8 4.1 3.2 3.0 3.9 2.6 7.2 10.6 4.2 3.7 12.8 5.1 2.9 13.9 5.8 3.0 20.0 4.4 21.7 3.6 5.9 5.4 3.2 2.9 4.3 3.5 3.7 3.3 4.7 2.6 1.8 10.4 11.4 1.5 7.0 9.3 3.6 3.2 1.1 10.9 2.2 2.8 9.9 2.2 3.5 0.8 5.1 4.9 5.0 3.0 3.6 1.6 3.1 5.3 0.0 3.8 16.2 4.6 4.5 0.7 5.4 2.0 1.8 4.4 2.1 6.8 1.3 0.9 4.5 5.1 6.5 3.8 0.0 0.8 0.6 9.0 2.7 2.1 7.5 5.7 0.7 7.3 2.2 1.1 5.9 3.8 4.4 5.1 2.5 2.6 3.8 7.7 4.6 5.4 1.1 4.6 0.0 2.8 0.7 2.0 4.6 3.1 4.1 1.0 1.3 1.8 2.3 1.0 2.2 2.7 3.7 3.5 3.4 0.1 1.4 3.8 3.5 4.8 4.5 4.1 2.6 3.9 2.6 2.6 3.0 3.6 3.7 3.4 28.9 29.6 25.1 6.5 2.4 6.8 16.3 8.6 3.5 1.9 4.2 5.3 11.5 20.0 5.5 2.1 2.1 6.0 20.9 7.9 5.4 270.4 3.7 11.8 4.6 4.8 3.0 33.8 3.8 1.0 9.2 2.6 3.1 15.8 13.1 5.3 15.5 4.7 5.0 24.5 11.4 6.1 6.3 1.7 163.5 9.3 4.8 5.4 19.7 4.4 4.7 6.2 39.2 7.1 2.5 6.1 6.0 1.8 2.2 29.6 6.7 10.2 2.6 6.6 6.4 5.1 9.4 4.8 1.7 2.4 0.8 3.9 77.6 15.2 2.3 CYP1B1 "CP1B, GLC3A" ENSG00000138061 "Cytochrome P450 family 1 subfamily B member 1" Q16678 2 38066973-38109902 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Steroid metabolism" "Lyase, Monooxygenase, Oxidoreductase" "Disease variant, Glaucoma, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 170.8;Prostatic glandular cells: 747.6;Urothelial cells: 498.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "classical monocyte: 156.9" "Lineage enriched" "Detected in many" 24 "monocytes: 156.9" "Cell line enhanced" "Detected in many" "ASC diff: 128.7;ASC TERT1: 136.8;HSkMC: 551.3;hTERT-RPE1: 128.9;SiHa: 270.0;U-87 MG: 142.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 34.6" "CAB011705, HPA026863" Approved Uncertain Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB011705: AB_731810, HPA026863: AB_10600900" "unprognostic (7.25e-3)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.68e-1)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (9.69e-2)" "unprognostic (4.20e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (4.39e-6)" "unprognostic (1.87e-3)" "unprognostic (1.81e-1)" "unprognostic (6.67e-2)" "prognostic unfavorable (2.76e-4)" 28.4 12.0 2.7 31.9 6.2 2.0 29.4 1.6 8.9 34.9 10.4 3.7 2.2 41.0 19.5 7.6 44.9 23.8 29.2 2.5 2.3 24.1 7.0 16.8 11.6 3.6 2.9 5.6 7.2 0.9 14.8 4.5 3.0 34.7 2.1 1.2 4.3 39.2 3.4 6.3 5.8 35.1 3.6 27.3 15.9 8.0 7.3 28.3 8.7 5.5 1.9 35.0 6.7 1.5 7.0 71.9 2.3 0.0 128.7 136.8 0.4 0.6 4.4 1.3 12.3 0.2 30.1 0.0 19.1 17.8 3.1 58.7 0.3 4.0 2.3 5.5 3.8 0.0 21.2 0.0 36.0 0.2 0.1 551.3 55.3 30.7 1.4 128.9 0.0 0.3 0.7 0.2 0.7 29.2 0.3 22.5 7.5 10.4 14.2 0.1 0.0 0.2 13.4 0.9 0.5 2.1 270.0 38.8 0.0 7.5 49.4 10.8 0.0 1.1 0.2 107.9 0.1 0.3 0.2 0.0 142.2 0.1 11.8 1.6 156.9 0.0 0.1 23.2 0.0 0.1 0.1 0.0 1.5 0.0 0.1 0.1 6.5 0.1 18.6 0.7 0.1 70.2 2.7 6.2 1.6 8.9 2.5 2.3 3.6 2.9 3.0 3.6 7.3 1.5 56.8 19.2 66.3 0.0 1.7 17.7 118.4 86.9 8.0 0.7 18.3 42.0 3.4 0.0 79.7 46.0 0.0 0.3 1.1 0.9 15.6 6.0 15.1 11.7 100.4 103.8 1.8 0.0 4.5 0.5 0.8 114.1 3.6 28.2 3.8 0.1 7.5 12.2 12.6 0.0 0.3 1.3 4.1 103.0 50.6 12.1 159.7 112.2 17.8 64.6 140.1 1.6 3.1 0.0 0.2 0.6 0.1 170.8 0.3 747.6 0.1 1.6 11.2 0.5 19.7 4.5 32.7 12.6 2.6 2.4 14.2 0.3 2.4 1.3 1.0 498.7 ATL2 ARL6IP2 ENSG00000119787 "Atlastin GTPase 2" Q8NHH9 2 38293954-38377285 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029108, HPA075302" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA029108: AB_10670557, HPA075302: AB_2732289" "unprognostic (5.80e-2)" "unprognostic (2.23e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.64e-2)" "unprognostic (1.18e-1)" "unprognostic (9.10e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.09e-2)" "unprognostic (1.27e-3)" "unprognostic (8.22e-2)" "unprognostic (6.86e-2)" "unprognostic (4.28e-2)" "unprognostic (2.09e-1)" "unprognostic (6.33e-2)" "unprognostic (1.84e-1)" 19.1 32.4 15.0 16.9 20.4 32.5 41.6 26.6 18.0 29.1 16.8 52.5 33.7 33.4 19.5 41.9 29.5 18.5 16.7 17.1 14.2 28.1 40.2 22.9 19.2 13.5 13.6 37.0 15.7 15.8 13.5 16.8 12.0 31.4 26.7 25.4 51.8 31.2 53.7 50.0 31.4 36.0 11.2 20.3 31.7 17.9 16.3 27.9 54.9 46.2 35.1 27.4 33.2 14.7 84.3 36.0 51.0 37.2 44.8 27.9 61.1 31.5 25.0 33.9 38.7 40.8 65.2 61.6 33.7 20.2 47.4 94.8 64.7 32.2 56.4 74.5 44.7 38.9 26.6 58.7 24.5 47.1 35.8 20.3 68.6 32.7 45.2 21.7 34.6 23.5 60.3 37.5 28.7 31.1 56.0 46.1 64.1 89.5 22.4 46.9 50.4 45.4 25.9 43.6 26.1 44.2 32.0 40.3 38.2 39.0 22.1 28.7 21.9 34.8 52.4 33.2 57.8 48.8 48.3 79.0 23.4 47.9 42.7 1.3 2.7 10.6 2.3 2.1 3.8 2.8 2.7 2.7 3.4 4.3 4.1 3.3 3.3 2.5 3.8 2.0 3.6 2.4 15.0 20.4 26.6 18.0 17.1 14.2 13.5 13.6 12.0 11.2 16.3 14.7 18.5 12.8 32.4 62.7 18.7 36.8 32.5 25.9 14.8 20.6 40.8 33.8 7.6 11.5 44.8 7.3 14.6 15.7 14.9 12.0 7.9 11.7 22.1 12.3 17.4 17.0 6.6 22.9 66.3 5.0 14.7 16.5 11.7 17.8 4.5 14.3 14.3 34.4 10.8 21.9 55.5 11.7 77.3 8.5 16.1 19.5 14.3 12.9 12.4 59.0 8.2 8.6 7.2 46.3 20.4 5.7 8.7 16.6 13.1 23.9 17.8 12.6 23.5 21.1 32.9 16.9 19.4 16.7 21.3 46.4 46.9 14.6 13.6 9.0 12.7 31.3 HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 155.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Mitochondria, Cytosol" "HPA046084: AB_10960895" "unprognostic (2.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.63e-2)" "unprognostic (5.18e-1)" "unprognostic (2.10e-3)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.22e-4)" "unprognostic (1.52e-2)" "unprognostic (1.52e-1)" "unprognostic (1.80e-1)" "unprognostic (4.20e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (2.25e-1)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (9.30e-2)" 16.0 16.4 16.3 12.5 20.7 51.7 14.7 19.3 21.3 16.2 12.9 16.1 15.5 18.2 13.9 10.2 16.7 14.1 12.8 28.6 8.3 11.1 10.8 16.4 12.5 5.9 8.1 16.9 15.9 16.8 9.2 13.1 7.2 13.9 11.8 26.6 12.8 15.0 13.8 11.4 12.7 12.8 7.8 12.0 15.7 22.6 9.3 31.0 17.7 11.9 9.6 15.2 12.8 15.8 36.7 16.9 48.2 28.4 22.9 21.6 30.1 33.8 27.5 28.8 24.1 19.0 20.7 0.5 29.5 30.4 30.9 23.0 30.7 25.4 29.6 54.6 26.8 26.7 32.3 48.6 21.6 49.9 26.4 16.9 19.6 24.0 26.5 28.5 30.6 23.9 45.9 79.7 34.3 17.2 54.9 27.2 48.4 35.2 30.6 10.6 33.9 18.1 25.0 47.2 32.9 36.9 29.8 25.8 26.0 26.7 21.8 21.6 32.0 21.5 32.1 23.8 28.1 43.4 46.9 0.3 18.5 12.2 26.8 10.6 6.3 9.7 10.3 3.2 17.9 0.4 24.2 18.9 12.0 1.9 7.2 4.6 4.2 6.8 1.2 0.2 38.5 5.8 16.3 20.7 19.3 21.3 28.6 8.3 5.9 8.1 7.2 7.8 9.3 15.8 17.0 19.2 23.4 26.8 5.5 28.7 35.2 16.5 33.0 13.3 18.0 15.2 18.8 8.6 18.8 27.6 8.4 26.2 6.4 13.9 19.6 22.4 155.6 18.1 18.8 20.1 14.4 22.5 68.6 24.3 28.9 26.0 32.1 11.6 9.5 26.3 22.5 7.4 24.4 6.7 40.1 15.4 6.1 15.0 90.2 48.7 27.7 23.1 39.2 37.5 24.5 22.3 2.1 48.7 28.4 21.2 14.2 52.3 23.0 23.6 16.6 18.6 14.5 11.7 39.5 22.6 28.4 91.1 28.8 19.4 21.3 22.2 48.0 22.3 18.8 21.4 GALM ENSG00000143891 "Galactose mutarotase" Q96C23 2 38666081-38741237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 86.5;kidney: 120.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 97.8;Proximal enterocytes: 161.1;Proximal tubular cells: 222.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 68.3" "Group enriched" "Detected in all" 5 "granulocytes: 39.1;T-cells: 68.3" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;Karpas-707: 71.1;U-266/70: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035472, HPA035473, HPA064835" Enhanced Approved Nucleoplasm NA NA 620000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA035472: AB_10669906, HPA035473: AB_2674642, HPA064835: AB_2732723" "unprognostic (5.02e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (9.20e-2)" "unprognostic (1.88e-2)" "unprognostic (9.99e-3)" "unprognostic (1.63e-2)" "unprognostic (2.80e-3)" "unprognostic (1.87e-1)" "unprognostic (7.17e-2)" "unprognostic (6.65e-2)" "unprognostic (6.45e-2)" "prognostic favorable (9.06e-5)" "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (4.34e-1)" "prognostic favorable (1.32e-4)" 9.0 86.5 5.2 12.2 5.1 3.8 10.4 6.0 6.1 9.3 8.3 34.7 71.4 8.1 23.0 5.8 35.8 16.5 13.0 4.9 4.8 120.2 72.5 14.3 16.0 5.4 6.1 15.5 15.0 21.3 3.0 7.7 5.4 10.2 33.3 4.4 8.7 20.8 13.1 3.8 52.8 10.4 5.7 6.6 14.9 4.4 7.0 11.0 15.1 12.3 10.2 10.8 6.4 6.0 0.2 27.1 8.1 0.0 27.3 15.4 14.9 3.2 10.3 7.5 12.2 32.4 14.4 10.9 18.9 15.3 14.5 4.3 11.7 0.7 14.5 49.5 19.3 5.9 7.1 62.7 10.0 2.4 0.4 11.1 0.4 17.5 0.0 10.5 8.2 0.0 17.2 71.1 13.9 0.9 23.4 41.0 12.4 59.2 8.6 15.2 0.6 21.3 9.3 45.1 1.5 11.2 0.1 18.9 14.7 10.2 9.0 5.4 3.4 2.5 0.5 18.6 1.0 76.4 54.3 0.3 17.9 7.0 0.3 39.1 4.8 4.2 21.5 3.3 31.8 6.8 33.1 31.2 10.3 4.7 11.7 10.2 11.3 5.5 0.7 0.8 68.3 11.9 5.2 5.1 6.0 6.1 4.9 4.8 5.4 6.1 5.4 5.7 7.0 6.0 9.7 28.9 11.0 13.4 10.0 6.6 6.7 3.4 10.8 3.6 7.8 4.2 23.4 24.3 6.5 69.9 0.0 23.6 19.0 83.2 25.4 12.1 1.4 28.5 11.6 10.0 13.2 8.2 2.3 15.1 31.4 16.1 17.9 10.1 7.0 16.8 14.6 48.1 94.8 3.3 1.4 40.5 4.1 18.6 43.6 1.3 20.2 34.7 17.8 4.7 9.9 38.2 18.6 0.5 1.3 6.8 64.5 97.8 14.7 5.7 161.1 222.1 14.8 6.8 6.6 16.6 10.4 1.0 2.3 3.2 6.0 6.3 44.0 43.3 80.4 5.7 SRSF7 "9G8, AAG3, HSSG1, RBM37, SFRS7, ZCCHC20, ZCRB2" ENSG00000115875 "Serine and arginine rich splicing factor 7" Q16629 2 38743599-38751494 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043850, HPA056926" Supported Enhanced Nucleoplasm NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA043850: AB_10964495, HPA056926: AB_2683277" "unprognostic (2.74e-1)" "unprognostic (1.53e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.86e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (2.90e-5)" "unprognostic (3.24e-2)" "unprognostic (2.53e-2)" "unprognostic (2.61e-1)" "unprognostic (3.75e-1)" "unprognostic (4.44e-3)" "prognostic unfavorable (3.18e-8)" "unprognostic (1.02e-2)" "unprognostic (1.87e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-3)" 68.3 44.5 30.5 59.3 31.8 132.8 53.3 32.3 36.0 37.3 33.9 55.0 30.4 43.8 40.7 65.3 45.2 24.0 37.7 32.3 33.6 47.0 49.4 50.5 72.0 30.8 30.2 34.6 33.6 36.1 30.0 50.7 30.8 38.9 52.2 25.0 37.4 34.5 41.9 37.8 46.2 52.9 33.3 45.8 50.6 54.0 30.7 87.0 34.3 27.7 90.1 68.4 40.9 34.4 271.3 229.3 304.4 197.1 91.8 71.8 213.7 225.2 96.6 222.9 177.9 272.9 202.4 436.1 150.9 148.2 206.9 149.2 385.7 277.1 266.7 274.7 240.9 264.3 154.8 281.2 78.1 329.3 185.4 43.4 92.8 153.3 295.0 94.3 187.9 180.3 388.5 171.1 191.6 298.9 421.2 289.9 331.5 313.3 208.4 367.8 253.4 248.0 168.2 257.3 207.2 201.6 215.3 190.1 156.5 189.7 172.8 295.0 163.1 134.3 210.2 116.3 317.6 186.6 297.8 658.9 159.1 339.1 189.3 23.4 71.2 27.8 59.8 103.3 65.0 63.3 46.1 60.3 142.4 40.7 51.4 59.7 6.8 65.7 61.7 85.8 53.4 77.5 30.5 31.8 32.3 36.0 32.3 33.6 30.8 30.2 30.8 33.3 30.7 34.4 445.1 80.1 208.8 31.3 453.7 259.5 460.8 255.9 220.3 122.7 226.9 367.2 67.8 87.2 177.0 64.4 118.9 313.7 730.0 214.7 156.5 195.4 173.6 104.6 193.5 245.7 178.0 153.5 96.6 132.2 478.1 264.0 258.9 130.4 320.4 273.2 150.0 85.3 241.9 121.1 82.2 222.5 140.4 123.4 242.6 45.2 138.5 289.2 152.9 65.6 222.6 253.9 239.9 74.9 100.8 149.0 179.3 109.9 337.7 309.9 192.1 94.1 116.4 225.8 118.3 317.9 408.1 286.7 287.3 163.0 243.5 250.2 652.4 186.4 242.8 344.7 GEMIN6 FLJ23459 ENSG00000152147 "Gem nuclear organelle associated protein 6" Q8WXD5 2 38751534-38785002 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 164.5;Spermatocytes: 87.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035726, HPA035727" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" "HPA035726: AB_10669528, HPA035727: AB_2674753" "unprognostic (1.97e-2)" "unprognostic (3.83e-1)" "unprognostic (2.32e-1)" "unprognostic (1.31e-2)" "unprognostic (1.86e-1)" "unprognostic (2.10e-2)" "unprognostic (3.82e-3)" "unprognostic (3.10e-2)" "unprognostic (8.13e-2)" "unprognostic (3.53e-3)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (2.47e-1)" "unprognostic (2.38e-1)" "unprognostic (1.04e-1)" "unprognostic (1.67e-2)" 6.5 10.1 7.7 7.7 8.2 3.6 8.3 8.2 10.9 6.7 8.2 6.9 9.0 6.5 10.3 7.1 9.0 5.5 6.0 7.7 7.6 12.5 13.8 5.3 10.8 7.7 7.8 9.8 6.8 7.5 6.2 7.4 8.1 5.6 8.5 6.1 6.1 5.2 13.1 5.4 7.8 8.7 7.4 7.9 7.2 19.6 8.0 8.1 6.7 7.0 12.4 7.7 5.8 10.5 38.8 31.2 21.3 24.9 27.3 23.8 36.4 32.4 16.1 28.1 23.3 33.1 18.1 52.8 36.3 16.8 39.4 18.1 33.5 31.6 40.7 45.5 42.3 34.4 17.9 54.4 18.7 29.0 17.2 16.3 22.9 37.6 18.5 19.2 29.9 14.1 35.9 17.9 28.4 27.4 35.1 37.0 36.6 45.4 37.0 24.1 37.6 28.9 25.8 13.4 26.6 41.9 8.3 31.1 25.3 24.7 16.0 9.8 16.4 27.1 34.6 21.4 49.1 36.7 77.4 50.6 21.8 43.0 27.7 3.1 24.3 7.8 19.6 28.6 21.7 32.4 20.3 20.3 24.0 29.5 24.4 25.5 3.6 26.3 26.6 17.7 31.3 22.4 7.7 8.2 8.2 10.9 7.7 7.6 7.7 7.8 8.1 7.4 8.0 10.5 11.8 12.8 24.0 1.0 18.7 8.3 10.3 31.5 7.4 6.9 13.9 21.1 9.1 14.3 22.3 11.0 4.2 29.7 7.5 7.5 29.4 22.2 164.5 28.6 21.3 14.9 1.2 18.5 1.7 17.8 37.8 16.1 16.8 8.3 12.6 19.0 16.8 33.5 26.4 11.8 1.8 10.7 6.1 19.5 15.5 29.0 20.5 15.0 10.6 1.9 23.4 9.2 15.5 1.5 1.2 19.1 11.4 11.3 13.3 10.7 21.2 68.5 32.6 7.9 19.7 10.7 15.7 87.8 18.3 16.1 11.5 7.3 12.5 30.5 17.7 7.7 DHX57 DDX57 ENSG00000163214 "DExH-box helicase 57" Q6P158 2 38797729-38875934 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 136.3;Late spermatids: 352.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036160 Uncertain Approved "Nucleoli,Intermediate filaments,Microtubules,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments, Microtubules" "Nucleoli, Cytosol" "HPA036160: AB_10670711" "unprognostic (6.78e-2)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (2.03e-3)" "unprognostic (3.25e-2)" "unprognostic (3.43e-1)" "prognostic unfavorable (3.32e-6)" "unprognostic (1.75e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.47e-1)" "unprognostic (3.88e-2)" "unprognostic (7.03e-3)" "unprognostic (1.77e-1)" 6.1 9.2 6.6 5.2 6.9 4.8 6.5 6.4 8.8 8.1 6.9 7.1 2.2 7.7 10.3 5.4 6.6 4.2 5.3 7.1 7.2 6.8 5.3 4.9 6.2 5.8 6.5 7.8 7.0 9.7 10.0 5.8 6.0 6.2 5.5 8.5 5.6 6.3 9.1 7.1 5.2 7.3 6.0 5.9 5.7 23.4 6.6 6.7 7.2 5.5 6.3 7.4 6.2 6.5 23.4 19.3 21.0 15.8 13.5 16.6 16.2 15.5 15.9 15.2 14.7 15.7 7.2 7.1 15.6 16.9 17.1 11.8 23.6 18.2 24.9 28.0 18.4 13.3 11.5 21.3 12.2 14.5 7.3 16.0 10.8 20.0 12.5 10.8 20.7 5.2 17.8 9.5 16.7 17.7 14.7 12.9 25.1 10.1 11.4 7.0 27.7 13.9 14.2 8.6 16.8 24.8 15.8 16.4 17.4 14.7 11.7 8.0 15.4 15.1 16.5 10.9 17.7 9.3 12.2 2.8 11.4 10.1 10.2 1.6 6.3 1.2 2.8 4.5 3.6 3.8 2.3 2.1 3.2 4.6 2.9 1.7 0.4 2.3 5.6 1.2 2.5 2.9 6.6 6.9 6.4 8.8 7.1 7.2 5.8 6.5 6.0 6.0 6.6 6.5 6.2 3.2 10.9 24.2 8.8 2.7 2.7 5.9 6.2 24.7 5.2 7.6 6.2 10.0 10.9 23.9 56.3 7.2 4.7 2.5 0.0 7.7 136.3 18.0 13.4 6.3 11.9 8.2 36.7 7.6 6.7 9.3 7.1 6.2 10.8 19.4 9.7 6.2 7.0 18.5 38.0 5.7 4.1 11.7 3.8 352.8 15.8 8.5 1.8 25.3 23.9 9.5 8.2 33.2 20.9 8.5 3.1 13.9 8.1 2.0 2.1 6.0 27.3 27.7 0.0 8.8 6.0 19.3 9.8 5.3 2.6 2.9 7.9 14.7 5.0 2.2 MORN2 MOPT ENSG00000188010 "MORN repeat containing 2" Q502X0 2 38875962-38929072 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 174.2" "Cell type enhanced" "Detected in many" "Early spermatids: 1976.5;Endometrial ciliated cells: 783.4;Late spermatids: 3753.7;Respiratory ciliated cells: 848.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057815 Approved Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA057815: AB_2683537" "unprognostic (7.28e-3)" "unprognostic (3.84e-2)" "unprognostic (8.65e-2)" "unprognostic (1.24e-2)" "unprognostic (1.84e-1)" "unprognostic (1.48e-1)" "unprognostic (1.24e-3)" "unprognostic (1.66e-2)" "unprognostic (6.01e-2)" "unprognostic (2.60e-2)" "unprognostic (2.93e-1)" "unprognostic (2.21e-1)" "unprognostic (8.37e-3)" "unprognostic (2.35e-1)" "unprognostic (1.09e-2)" "unprognostic (3.55e-1)" "unprognostic (8.80e-2)" 13.5 30.5 41.9 6.2 44.6 9.7 20.6 42.8 55.9 30.5 62.8 14.5 6.6 16.6 73.3 13.7 96.3 16.0 26.2 42.4 44.9 69.3 17.6 18.0 5.5 45.0 46.4 19.4 20.2 79.5 56.8 8.0 45.7 18.0 13.5 37.6 21.3 18.8 20.0 10.2 8.1 11.3 43.7 6.6 15.2 174.2 43.6 8.2 46.0 17.3 5.7 14.5 13.2 44.3 60.9 30.5 37.2 46.0 40.4 60.5 21.0 27.7 42.9 42.5 40.2 18.3 33.5 3.8 21.8 40.9 42.4 15.9 16.5 34.9 63.4 25.3 32.8 12.9 32.6 46.1 34.8 21.2 9.2 35.6 42.8 51.5 18.9 54.0 39.9 11.7 22.7 8.9 35.8 58.6 9.3 40.5 27.6 40.0 31.7 5.2 38.8 13.3 83.0 33.4 37.1 49.4 41.3 27.0 59.6 21.7 36.5 28.5 26.5 30.2 29.8 48.0 44.1 16.6 26.4 2.3 68.8 6.0 54.4 1.5 8.3 1.2 1.6 6.7 3.1 2.5 1.9 2.4 5.9 2.7 3.2 3.3 0.7 2.7 5.5 3.0 4.0 3.8 41.9 44.6 42.8 55.9 42.4 44.9 45.0 46.4 45.7 43.7 43.6 44.3 14.1 16.0 25.3 2.6 7.9 9.7 25.5 103.9 10.2 16.7 29.5 45.7 40.5 35.8 90.9 60.7 10.4 15.9 4.2 19.5 270.1 61.4 1976.5 783.4 34.1 16.0 22.9 7.4 2.5 44.4 22.9 28.8 18.8 43.6 9.5 35.2 12.8 24.5 23.6 16.8 2.3 18.1 73.2 9.0 6.7 3753.7 53.4 15.1 23.2 0.0 10.2 106.7 3.1 1.5 1.8 41.0 34.3 51.6 5.5 22.4 7.4 396.6 848.6 35.1 26.3 21.3 40.5 530.7 92.0 15.7 10.5 7.7 6.1 51.8 22.0 30.0 ARHGEF33 ENSG00000214694 "Rho guanine nucleotide exchange factor 33" A8MVX0 2 38889875-38975454 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.8;Excitatory neurons: 15.2;Late spermatids: 26.8;Spermatocytes: 34.7;Spermatogonia: 35.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Group enriched" "Detected in some" 4 "BEWO: 5.6;HeLa: 2.6;SiHa: 7.2" "Region enriched" "Detected in many" 32 "cerebellum: 280.4" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "HPA034661, HPA041051" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA034661: AB_10669679, HPA041051: AB_2677274" "unprognostic (8.38e-2)" "unprognostic (7.05e-4)" "unprognostic (1.95e-1)" "unprognostic (4.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-1)" "unprognostic (3.66e-1)" "unprognostic (3.37e-1)" "unprognostic (5.82e-2)" "unprognostic (2.05e-3)" "unprognostic (4.99e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" 0.4 2.1 4.9 0.6 5.2 0.0 0.9 22.6 5.8 1.5 4.4 1.0 0.1 1.5 2.6 0.4 1.4 0.8 0.5 4.9 4.1 0.9 0.2 0.7 0.3 4.1 5.4 3.5 0.4 0.7 3.4 0.5 4.0 0.9 0.3 4.0 0.5 0.7 0.3 0.8 0.4 0.5 3.1 0.3 0.5 5.7 7.2 0.1 1.1 0.0 0.2 0.7 0.7 5.0 0.2 0.0 0.2 0.1 0.1 0.1 5.6 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.1 2.6 0.1 0.4 0.2 0.1 0.5 0.6 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.3 0.2 7.2 0.3 0.0 0.6 0.0 0.2 0.4 0.1 0.9 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.2 3.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.9 5.2 22.6 5.8 4.9 4.1 4.1 5.4 4.0 3.1 7.2 5.0 0.4 0.0 1.5 7.8 0.1 0.0 0.1 0.0 0.6 2.5 0.3 0.6 0.8 1.5 0.6 0.0 0.0 1.1 0.0 0.1 0.0 0.1 34.8 1.8 1.2 0.4 0.0 2.7 15.2 0.0 1.9 1.2 0.0 0.2 0.0 1.4 0.0 0.2 1.0 0.0 11.4 0.4 0.0 0.0 0.0 26.8 1.2 0.2 0.0 1.9 0.1 3.6 0.0 5.5 3.4 0.0 0.0 3.4 0.0 0.1 0.0 0.4 3.9 2.9 0.0 0.3 1.5 34.7 35.6 0.1 0.1 0.5 0.0 2.0 0.1 0.2 SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38981549-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.6;Inhibitory neurons: 224.0;Microglial cells: 161.1;Oligodendrocyte precursor cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 134.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "CAB005396: AB_2270724" "unprognostic (6.68e-2)" "unprognostic (2.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.14e-3)" "unprognostic (4.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.74e-3)" "unprognostic (4.55e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.38e-2)" "unprognostic (8.96e-3)" "unprognostic (7.61e-2)" "unprognostic (5.59e-2)" "unprognostic (1.33e-2)" 17.5 8.4 8.2 14.8 10.2 10.8 9.8 14.1 10.3 13.1 6.8 11.0 14.7 14.3 10.3 12.3 11.2 13.5 9.5 9.7 10.8 11.0 11.9 11.0 16.9 9.5 10.2 20.1 9.1 17.1 0.1 17.0 9.5 13.4 12.9 13.2 9.0 12.2 13.7 9.4 15.6 13.8 6.7 12.5 11.5 10.3 8.7 15.4 15.1 16.4 17.8 13.5 0.1 10.6 24.8 15.1 22.8 16.2 29.1 35.0 23.8 15.3 18.7 12.0 11.4 16.3 14.6 35.8 10.3 20.1 18.5 14.4 26.9 13.9 22.1 36.3 11.9 55.5 12.8 22.0 11.8 17.9 134.9 21.6 20.5 16.3 15.8 19.5 18.9 8.1 23.9 16.4 15.4 13.5 19.4 15.8 14.3 30.4 10.4 21.5 20.5 10.5 12.1 19.8 22.0 22.0 18.3 32.3 18.2 18.5 10.4 9.3 21.5 19.8 16.0 15.7 15.4 19.3 20.9 18.4 15.8 17.3 12.0 0.0 0.5 1.4 1.3 0.7 1.9 1.6 1.3 1.4 0.4 1.0 1.5 1.4 0.6 2.7 0.9 0.6 0.9 0.4 8.2 10.2 14.1 10.3 9.7 10.8 9.5 10.2 9.5 6.7 8.7 10.6 72.3 16.0 31.2 120.5 20.9 20.8 15.5 10.9 19.9 19.0 18.4 16.9 33.9 18.6 17.8 9.2 10.4 10.2 27.6 19.5 1.9 11.0 64.9 30.0 36.6 43.2 12.0 12.8 226.6 11.9 8.4 22.9 21.4 34.0 3.8 30.0 12.8 18.6 10.3 8.4 224.0 16.9 26.4 19.1 13.2 11.4 22.7 19.9 7.2 161.1 19.6 15.1 26.8 173.4 125.2 14.2 14.6 21.8 37.5 25.3 28.0 12.8 20.4 11.2 6.6 27.1 22.7 11.3 7.0 17.1 25.3 10.4 33.2 18.4 17.0 28.4 CDKL4 ENSG00000205111 "Cyclin dependent kinase like 4" Q5MAI5 2 39175646-39229588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 2.0;testis: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.8;Excitatory neurons: 5.4;Late spermatids: 6.8;Respiratory ciliated cells: 5.9;Spermatocytes: 8.7;Spermatogonia: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RT4: 1.3;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" HPA067895 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA067895: AB_2685920" "unprognostic (3.57e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.98e-2)" "unprognostic (3.29e-1)" "unprognostic (7.46e-3)" "unprognostic (3.26e-2)" "unprognostic (4.26e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-3)" "unprognostic (1.77e-2)" "unprognostic (8.43e-2)" "unprognostic (8.45e-4)" "unprognostic (8.59e-2)" "unprognostic (4.95e-1)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" 0.1 0.4 0.6 0.0 0.6 0.0 0.1 0.7 0.7 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.7 1.1 0.1 0.0 0.2 0.1 0.5 0.6 0.1 0.1 0.2 0.5 0.4 0.5 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 2.9 1.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 2.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 1.3 0.2 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.6 0.6 0.7 0.7 0.7 1.1 0.5 0.6 0.5 0.2 1.0 0.4 0.5 3.2 0.0 0.7 0.0 0.1 0.2 0.3 0.0 0.1 0.6 0.5 0.2 0.0 2.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 11.8 1.2 0.3 0.3 0.0 0.0 5.4 0.2 0.4 0.2 1.1 1.8 0.0 0.2 0.0 0.1 0.2 0.0 3.4 0.0 2.0 0.0 0.0 6.8 0.3 0.2 0.0 1.9 0.0 0.2 0.0 1.5 0.4 0.4 0.1 0.4 0.1 0.4 0.0 0.3 5.9 0.8 0.0 0.5 0.1 8.7 4.3 0.0 0.0 0.0 0.3 0.2 0.0 0.1 MAP4K3 "GLK, MAPKKKK3, RAB8IPL1" ENSG00000011566 "Mitogen-activated protein kinase kinase kinase kinase 3" Q8IVH8 2 39249266-39437301 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 118.8;Excitatory neurons: 201.0;Inhibitory neurons: 198.3;Microglial cells: 144.3;Oligodendrocyte precursor cells: 160.4;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "AF22: 102.3;RT4: 97.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030380 Approved Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" Nucleoplasm "HPA030380: AB_10601132" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (5.87e-3)" "unprognostic (7.34e-3)" "unprognostic (6.77e-2)" "unprognostic (2.57e-1)" "unprognostic (1.05e-2)" "unprognostic (6.73e-2)" "unprognostic (1.66e-1)" "unprognostic (6.73e-2)" "unprognostic (4.33e-3)" "unprognostic (4.26e-2)" "unprognostic (2.12e-1)" "unprognostic (3.08e-2)" "unprognostic (3.30e-1)" "unprognostic (2.43e-1)" "unprognostic (5.08e-2)" 15.8 17.1 11.6 6.7 12.5 10.5 16.6 21.6 16.7 15.0 15.3 15.5 13.2 17.2 13.4 10.2 13.6 14.7 19.3 14.2 11.2 24.5 15.1 13.3 6.1 9.9 10.0 20.2 12.2 25.3 12.2 27.4 10.0 16.9 13.0 28.0 10.8 14.0 30.9 16.4 14.3 14.5 11.3 11.6 26.6 21.3 10.2 8.1 24.4 22.2 6.1 18.3 11.4 14.4 25.6 15.6 102.3 16.3 16.3 32.4 28.0 22.1 28.3 21.6 18.3 13.3 12.6 5.5 24.3 15.3 22.1 13.6 39.0 19.7 32.6 6.3 16.0 9.2 10.8 30.9 42.3 4.0 14.5 29.3 19.0 28.1 30.1 22.6 18.8 5.0 12.1 9.9 29.2 13.9 9.0 6.0 30.7 24.0 23.4 9.9 33.3 4.2 28.3 97.3 18.2 20.7 12.9 20.7 58.8 32.0 13.9 5.6 15.4 16.7 19.7 15.0 12.1 15.1 9.3 1.9 20.5 6.6 19.0 0.7 0.1 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 11.6 12.5 21.6 16.7 14.2 11.2 9.9 10.0 10.0 11.3 10.2 14.4 36.2 3.2 8.4 118.8 8.1 17.6 17.9 11.0 16.5 24.7 14.1 12.3 38.2 21.5 16.5 22.0 25.0 13.1 4.1 12.5 19.6 10.3 45.1 22.3 19.9 20.6 9.6 4.6 201.0 12.4 6.7 18.2 25.5 59.4 2.5 15.6 14.3 18.6 9.7 6.7 198.3 13.9 2.0 10.9 20.6 103.0 20.8 14.4 5.4 144.3 4.4 13.2 3.1 160.4 129.2 17.5 5.7 17.7 14.3 18.6 14.0 11.9 19.5 37.9 19.7 18.7 17.6 22.6 19.8 11.8 19.2 10.4 5.9 17.4 10.6 30.2 TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.4;Excitatory neurons: 109.1;Inhibitory neurons: 109.2;Oligodendrocyte precursor cells: 33.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 138.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" 5.9 7.6 65.4 0.6 71.3 0.2 6.2 135.5 104.1 4.1 38.6 8.9 1.9 3.6 1.5 1.8 6.3 2.7 4.5 71.7 51.3 42.7 9.9 6.7 0.5 64.7 54.9 5.9 4.6 2.3 12.9 3.2 65.5 11.6 1.7 15.7 21.9 1.6 2.8 3.3 3.2 2.4 65.7 2.6 8.6 2.2 51.5 0.5 12.3 1.9 0.5 3.9 3.0 108.0 0.0 0.0 138.7 0.1 0.1 3.3 0.2 0.6 0.1 0.0 0.3 0.0 0.3 0.0 3.7 0.0 0.0 0.3 4.5 0.0 0.5 0.3 0.1 0.0 0.0 0.4 1.1 0.1 0.0 2.6 0.3 0.0 0.4 4.3 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 17.7 0.2 0.1 1.7 0.0 0.0 1.0 0.2 25.7 0.6 0.0 0.6 0.3 23.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 71.3 135.5 104.1 71.7 51.3 64.7 54.9 65.5 65.7 51.5 108.0 3.2 0.0 2.0 14.7 0.0 0.4 0.5 0.6 1.8 9.1 1.1 32.4 3.9 0.0 1.3 12.9 6.2 0.3 0.1 0.8 0.0 0.2 0.4 3.0 1.2 4.3 16.1 0.0 109.1 0.2 0.0 2.6 0.0 6.5 0.0 1.4 0.7 0.5 0.2 1.7 109.2 0.4 2.0 0.0 0.4 0.1 0.0 0.2 1.8 7.5 0.0 1.1 0.0 33.7 19.3 0.4 0.3 0.0 0.0 3.7 0.5 0.7 4.3 6.1 0.0 0.9 0.6 0.2 0.5 0.1 0.6 0.5 0.1 0.5 0.4 0.3 THUMPD2 "C2orf8, MGC2454" ENSG00000138050 "THUMP domain containing 2" Q9BTF0 2 39736060-39779267 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043042, HPA058025" Approved Uncertain Nucleoplasm Yes No "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA043042: AB_10964424, HPA058025: " "unprognostic (6.30e-2)" "unprognostic (9.12e-3)" "unprognostic (2.48e-2)" "unprognostic (4.62e-3)" "unprognostic (2.16e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.22e-1)" "unprognostic (2.31e-2)" "unprognostic (1.30e-1)" "unprognostic (2.72e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (7.27e-5)" "unprognostic (2.17e-1)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.14e-3)" 2.4 2.0 2.6 0.5 2.5 1.7 2.1 2.9 3.0 1.9 2.6 1.9 0.5 1.7 0.2 3.5 1.5 0.5 3.3 2.6 2.6 2.4 2.3 2.2 1.4 2.6 2.8 3.2 2.2 0.5 2.3 0.4 2.6 2.0 0.7 0.4 2.1 0.4 6.0 2.5 2.0 0.4 2.4 2.5 2.2 0.9 2.6 2.0 2.1 4.0 1.5 2.1 2.4 2.8 4.9 4.7 1.0 6.5 2.3 3.3 2.7 1.3 2.5 3.0 3.1 5.0 4.5 7.8 2.7 1.6 7.6 2.0 9.7 4.4 3.2 13.1 10.8 4.7 3.0 5.7 4.1 6.3 2.4 3.9 3.2 3.1 1.0 2.9 4.9 1.5 5.9 1.8 6.1 2.3 3.3 5.0 0.0 13.0 2.9 3.4 4.2 5.4 2.9 2.6 5.7 3.1 1.3 5.6 3.2 0.4 1.8 3.9 2.5 4.0 2.5 1.1 3.6 2.4 3.1 5.1 2.0 11.4 3.2 0.0 0.6 0.0 0.1 0.4 0.6 0.7 0.4 0.1 0.5 0.3 0.6 0.4 0.1 0.4 0.1 0.9 0.1 0.6 2.6 2.5 2.9 3.0 2.6 2.6 2.6 2.8 2.6 2.4 2.6 2.8 17.4 25.6 20.6 26.8 17.8 14.3 29.0 19.5 15.9 26.8 14.4 29.8 23.7 8.6 20.3 14.7 18.8 11.5 23.0 7.2 19.6 16.6 4.5 7.5 16.9 13.7 9.6 23.8 42.2 13.7 13.6 18.4 17.9 10.9 7.0 19.2 10.0 9.9 11.3 6.7 41.6 8.1 8.2 10.9 7.7 4.0 28.0 10.0 5.4 45.0 11.8 12.1 15.5 45.2 30.3 16.7 17.1 25.6 8.2 23.7 10.3 16.4 10.9 21.1 6.6 20.5 16.0 9.1 19.7 16.9 13.5 6.8 12.6 22.2 13.5 22.7 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 PKDCC "SgK493, Vlk" ENSG00000162878 "Protein kinase domain containing, cytoplasmic" Q504Y2 2 42048021-42058517 "Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins" "Differentiation, Osteogenesis, Protein transport, Transport" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 85.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 71.9;Fibroblasts: 55.4;Leydig cells: 137.6;Peritubular cells: 112.1;Rod photoreceptor cells: 95.9;Theca cells: 135.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 85.9;ASC diff: 61.7;CACO-2: 101.0;HHSteC: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026427, HPA026442, HPA026526" Approved "Secreted to blood" NA NA 80000 "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "HPA026427: AB_10600773, HPA026442: AB_10601237, HPA026526: AB_10602416" "unprognostic (6.77e-2)" "unprognostic (3.35e-1)" "unprognostic (1.04e-2)" "unprognostic (3.59e-3)" "unprognostic (8.31e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-2)" "unprognostic (5.79e-3)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (2.14e-2)" "unprognostic (9.08e-2)" "unprognostic (2.62e-1)" "unprognostic (4.73e-3)" "unprognostic (2.58e-3)" 25.7 11.3 3.1 4.9 3.8 0.8 16.1 0.8 6.2 31.8 6.4 20.3 10.7 25.7 2.1 2.2 24.2 3.3 37.6 4.8 1.0 10.7 6.9 16.5 2.1 1.5 1.6 50.1 7.0 1.1 6.8 3.6 1.3 12.2 5.7 5.3 20.7 5.8 85.5 3.8 13.7 9.8 1.4 9.6 9.6 14.8 2.1 6.4 5.1 27.7 1.4 32.5 17.4 4.7 0.0 5.5 14.0 85.9 61.7 0.7 5.3 0.2 0.0 1.2 1.5 101.0 0.2 0.0 0.3 1.7 1.8 0.0 1.3 0.0 0.0 8.1 3.5 0.2 3.3 27.0 53.7 0.0 1.2 5.7 0.3 0.2 0.0 0.6 0.7 0.0 1.2 0.0 0.3 0.3 0.0 0.3 23.8 6.8 1.7 0.0 27.3 0.0 0.0 0.0 2.8 5.1 1.3 0.0 0.2 16.3 0.1 0.7 0.0 0.6 2.8 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.8 0.8 6.2 4.8 1.0 1.5 1.6 1.3 1.4 2.1 4.7 28.8 19.2 0.5 4.2 0.3 3.2 0.2 0.0 0.0 4.7 1.3 2.0 9.2 1.5 0.0 1.8 16.7 0.5 0.6 22.8 0.0 2.1 1.1 6.0 31.4 3.1 71.9 0.0 22.8 1.3 1.3 55.4 2.6 26.3 0.0 4.5 2.9 2.7 0.6 0.0 3.3 18.6 0.0 0.6 3.1 5.4 137.6 0.6 1.8 3.7 0.0 21.3 0.0 10.1 1.8 1.9 16.0 112.1 0.0 0.8 15.2 3.9 0.0 95.9 13.1 14.2 15.1 0.7 1.7 0.0 1.8 0.3 0.8 135.4 35.9 0.1 EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported Microtubules,Cytosol NA NA 25000 "Cluster 13: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Microtubules Cytosol "HPA036687: AB_2675251, HPA036688: AB_10671968, HPA065337: AB_2685474" "unprognostic (1.70e-1)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "unprognostic (3.53e-3)" "unprognostic (1.79e-2)" "unprognostic (9.19e-2)" "unprognostic (8.61e-3)" "unprognostic (1.61e-2)" "unprognostic (2.96e-3)" "unprognostic (6.80e-2)" "unprognostic (7.44e-2)" "unprognostic (1.60e-2)" "unprognostic (1.86e-2)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (2.13e-2)" 11.2 13.7 1.5 32.4 2.5 41.1 14.1 1.0 1.4 11.7 3.9 23.6 38.8 11.1 4.6 11.1 9.9 19.9 4.6 1.6 1.0 19.4 38.1 24.3 28.3 2.2 1.6 8.9 24.3 13.8 4.3 35.6 1.6 9.7 23.7 10.3 21.0 8.0 2.4 18.3 36.5 14.1 2.0 28.3 20.9 20.4 3.7 14.9 21.5 3.9 30.0 27.3 5.7 2.8 45.1 76.7 43.7 34.9 15.6 25.4 47.7 27.3 21.4 29.7 28.5 80.8 55.1 41.1 18.5 26.9 45.6 22.7 38.0 26.3 51.3 80.8 31.8 37.7 23.5 186.3 19.7 28.8 37.1 27.9 9.8 39.4 26.5 14.4 20.9 14.0 37.9 40.3 32.5 26.4 27.3 7.7 44.8 57.8 21.9 27.8 69.2 24.3 24.2 64.3 42.9 86.3 26.9 27.7 20.8 39.6 14.4 11.4 24.6 30.1 39.9 24.3 24.9 44.9 33.3 34.6 26.3 27.0 21.6 5.6 4.7 9.9 9.0 13.7 19.0 13.9 15.0 14.8 4.1 9.1 12.8 9.6 12.3 11.9 14.6 5.3 22.3 7.6 1.5 2.5 1.0 1.4 1.6 1.0 2.2 1.6 1.6 2.0 3.7 2.8 47.0 60.9 107.3 37.9 137.6 67.3 74.3 60.5 75.1 35.1 53.5 45.7 7.0 51.5 60.9 40.5 47.9 143.0 120.8 57.0 17.6 34.0 33.1 33.4 50.1 50.8 102.3 20.8 54.2 75.4 47.5 55.3 76.0 86.6 48.1 80.7 43.9 61.9 65.6 16.8 60.0 69.3 34.6 40.3 56.6 31.0 23.9 74.8 16.0 119.9 38.4 35.1 47.4 62.8 32.9 38.1 58.9 23.0 139.5 65.4 51.3 41.3 28.6 47.3 6.6 25.0 47.6 46.5 39.4 73.4 79.7 118.9 223.8 42.0 85.0 96.4 COX7A2L "COX7AR, COX7RP, EB1, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "CAB073545: , HPA059124: AB_2683912" "unprognostic (3.90e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (5.45e-2)" "unprognostic (4.60e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-1)" "unprognostic (1.66e-2)" "unprognostic (2.43e-1)" "unprognostic (7.07e-3)" "unprognostic (1.54e-2)" "unprognostic (2.76e-1)" "unprognostic (5.53e-2)" "unprognostic (6.19e-2)" "unprognostic (1.02e-1)" 79.5 222.7 53.9 18.7 57.5 56.9 78.3 53.1 62.5 93.0 56.1 84.0 32.5 74.8 42.8 60.8 81.0 22.7 102.6 56.2 56.9 130.2 113.9 64.0 32.3 54.8 53.2 127.6 89.8 71.8 128.0 22.8 55.9 71.6 39.2 62.4 67.2 32.4 83.3 72.1 66.0 28.0 53.0 65.9 99.9 54.5 54.8 42.0 56.6 39.3 35.0 74.2 70.4 53.4 72.1 50.7 49.0 54.0 92.4 121.8 55.8 58.2 85.8 51.5 66.0 56.9 48.9 63.1 54.8 71.9 70.0 30.3 65.5 65.9 80.1 99.5 47.5 46.0 31.9 95.5 106.2 66.5 42.5 123.7 128.6 55.5 132.6 78.5 77.4 49.7 64.1 101.1 83.9 68.6 75.3 96.8 45.3 91.6 48.1 40.7 87.5 51.6 84.6 57.4 55.8 63.7 25.7 60.4 166.1 58.2 43.2 73.3 60.1 45.4 61.2 55.3 57.1 84.1 98.7 46.0 63.1 68.8 39.9 103.7 78.6 43.2 57.9 71.1 75.6 72.6 70.4 67.1 84.4 61.9 77.8 67.0 34.1 69.1 80.1 99.0 87.3 189.3 53.9 57.5 53.1 62.5 56.2 56.9 54.8 53.2 55.9 53.0 54.8 53.4 150.7 32.1 76.3 11.4 152.5 265.6 197.9 387.2 135.5 114.8 206.8 237.6 158.7 171.6 173.4 149.0 37.5 228.1 163.4 103.8 645.6 239.1 27.4 189.5 133.3 144.0 288.7 188.7 28.2 229.5 316.2 128.5 123.8 175.9 87.0 155.8 132.1 222.3 234.0 131.2 26.1 285.8 282.8 236.3 225.1 26.3 161.8 161.6 220.5 19.7 298.4 326.8 166.9 13.6 24.5 202.1 173.0 158.7 167.7 214.2 247.1 492.4 160.9 123.6 111.7 137.6 175.2 220.4 270.8 162.7 245.5 329.6 161.8 296.2 257.0 241.7 KCNG3 Kv6.3 ENSG00000171126 "Potassium voltage-gated channel modifier subfamily G member 3" Q8TAE7 2 42442017-42493982 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 5.7" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 12.1;Excitatory neurons: 16.4;Glandular and luminal cells: 12.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.1" "Group enriched" "Detected in many" 8 "amygdala: 1.8;basal ganglia: 2.3;cerebral cortex: 3.7;hippocampal formation: 5.7;pons: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HAP1: 4.7;HMC-1: 16.2;NTERA-2: 10.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041625 Approved "Cytoplasmic bodies" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Cytoplasmic bodies" "HPA041625: " "unprognostic (1.56e-1)" "unprognostic (4.22e-3)" "unprognostic (2.48e-1)" "unprognostic (7.67e-3)" "unprognostic (7.95e-2)" "unprognostic (9.14e-3)" "unprognostic (4.83e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (2.56e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (2.76e-1)" "unprognostic (6.47e-2)" "unprognostic (1.23e-1)" 0.0 0.9 1.8 0.1 2.3 0.0 0.0 0.0 3.7 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.5 0.0 0.4 0.0 1.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.2 0.0 4.7 0.0 0.0 0.0 2.5 0.0 0.5 0.9 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.0 0.1 0.9 0.0 10.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.5 0.6 1.0 1.6 0.4 1.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.3 0.0 3.7 5.7 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.1 3.2 1.1 0.7 0.0 1.3 0.3 0.0 0.0 1.6 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.6 12.1 1.5 0.2 1.8 0.0 16.4 0.0 0.0 0.5 0.0 12.8 0.0 0.3 0.0 0.0 0.1 0.0 1.4 0.4 0.0 0.0 0.3 0.2 1.8 0.1 0.0 0.0 0.0 2.0 0.0 1.5 0.4 0.2 0.2 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 1.1 0.0 1.1 0.1 0.1 1.8 0.3 0.3 MTA3 KIAA1266 ENSG00000057935 "Metastasis associated 1 family member 3" Q9BTC8 2 42494569-42756947 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 137.0;Oligodendrocyte precursor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039433 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA039433: AB_10794747" "unprognostic (5.40e-2)" "unprognostic (4.89e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.13e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (5.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (1.28e-2)" 11.8 41.8 16.4 5.6 18.9 1.6 14.9 9.1 19.4 18.5 7.1 16.6 7.8 16.8 27.5 21.8 16.1 10.0 12.4 21.9 14.9 13.6 7.9 8.8 10.7 12.3 13.9 29.2 18.8 17.3 15.1 15.3 18.8 14.4 13.2 9.3 13.6 16.8 9.1 19.1 11.4 12.0 11.7 7.8 16.8 21.0 16.1 70.4 12.6 9.9 14.5 15.3 17.8 14.8 13.0 16.6 20.1 14.3 17.4 28.0 46.6 7.4 18.6 21.7 19.2 22.2 26.2 45.4 12.6 22.1 15.9 8.2 51.6 25.2 34.2 14.1 21.0 6.7 8.8 36.4 21.9 5.0 29.0 29.5 29.1 13.4 16.6 28.1 30.4 23.9 16.5 6.1 25.7 27.8 30.3 22.0 84.4 20.8 9.7 18.4 18.9 0.0 25.7 12.1 12.3 37.1 13.5 45.5 17.8 61.6 23.2 7.0 14.2 8.9 12.1 7.2 8.1 11.5 4.7 63.5 12.6 5.7 11.1 2.5 0.9 0.0 1.7 0.6 2.6 1.2 2.0 2.9 1.5 1.3 4.4 3.0 0.2 1.8 0.9 0.4 1.1 1.5 16.4 18.9 9.1 19.4 21.9 14.9 12.3 13.9 18.8 11.7 16.1 14.8 12.7 12.8 12.5 60.4 10.8 15.3 21.1 33.0 15.4 0.0 24.6 19.6 12.5 15.7 25.7 22.0 0.0 58.5 5.1 19.1 17.6 22.9 10.7 44.5 23.1 13.1 9.6 2.5 137.0 28.0 42.0 21.7 31.1 32.3 12.0 72.3 20.7 13.3 12.4 0.0 81.8 20.0 50.8 6.6 7.1 26.0 33.8 5.2 17.8 53.4 6.9 0.0 9.2 106.1 65.9 20.2 21.8 39.9 10.9 17.7 25.2 33.1 18.4 0.0 13.1 15.8 35.9 25.5 41.1 24.5 18.3 59.9 12.6 44.5 21.5 17.3 OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762481-42764261 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 56.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 8.3;Proximal enterocytes: 16.1;Skeletal myocytes: 12.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 67.0;eosinophil: 144.5" "Lineage enriched" "Detected in many" 79 "granulocytes: 144.5" "Cell line enhanced" "Detected in some" "CACO-2: 6.6;Hep G2: 7.6;HMC-1: 6.1;REH: 3.2;THP-1: 2.8" HPA051433 Approved NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" 2.1 1.8 1.2 1.5 1.2 2.4 1.9 0.3 1.8 6.9 1.1 3.9 5.0 3.1 2.3 2.4 3.6 1.4 2.4 1.3 0.6 8.4 56.3 1.9 1.2 0.9 0.9 9.1 7.2 0.3 3.8 1.7 0.7 6.6 1.8 0.3 1.5 1.7 0.9 3.1 8.5 0.8 0.4 4.9 2.3 1.2 1.0 1.0 2.2 0.4 1.1 6.0 4.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 6.6 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.3 2.2 0.0 7.6 0.0 0.1 6.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 1.4 0.0 0.0 3.2 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.6 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 67.0 1.8 144.5 0.1 0.6 0.0 0.2 0.0 0.0 1.4 0.1 0.0 0.0 16.9 0.0 0.1 0.2 0.0 0.8 1.2 1.2 0.3 1.8 1.3 0.6 0.9 0.9 0.7 0.4 1.0 0.6 0.1 0.0 0.5 0.7 0.1 0.5 0.6 0.2 0.6 1.6 0.4 0.6 0.4 2.8 0.2 1.8 0.0 0.1 0.0 1.9 1.9 0.6 0.0 0.1 2.0 0.1 1.2 0.0 0.0 2.0 0.1 2.0 0.0 0.1 2.5 0.4 0.4 8.3 1.0 0.0 0.0 3.4 0.0 1.3 1.2 0.3 3.4 1.5 3.6 1.0 3.0 0.9 0.0 0.0 0.0 0.6 5.3 1.9 0.0 0.5 16.1 4.9 0.2 0.0 0.0 12.9 1.1 0.3 0.2 0.3 0.1 0.3 1.1 0.3 5.1 0.3 HAAO ENSG00000162882 "3-hydroxyanthranilate 3,4-dioxygenase" P46952 2 42767089-42792593 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 295.8" "Group enriched" "Detected in many" 5 "Hepatocytes: 209.8;Proximal enterocytes: 236.8;Proximal tubular cells: 162.7" "Group enriched" "Detected in all" 5 "liver cancer: 46.5;renal cancer: 13.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 23.2" "Group enriched" "Detected in many" 5 "dendritic cells: 23.2;granulocytes: 19.2;monocytes: 17.4" "Cell line enhanced" "Detected in some" "CACO-2: 14.0;Hep G2: 49.4;REH: 9.9;THP-1: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036394, HPA042024" Enhanced NA NA 580000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA036394: AB_10673131, HPA042024: AB_2677803" "unprognostic (6.97e-3)" "unprognostic (1.86e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-1)" "unprognostic (7.23e-3)" "prognostic favorable (5.77e-4)" "unprognostic (6.20e-2)" "unprognostic (7.58e-2)" "unprognostic (5.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (2.03e-1)" 8.7 5.4 1.8 5.9 2.1 4.1 12.9 2.1 2.5 16.0 3.3 13.2 23.1 10.5 14.5 6.0 10.6 6.1 7.0 1.8 2.3 41.8 295.8 5.7 6.1 2.0 2.5 14.0 26.3 2.9 4.5 8.5 2.3 10.1 11.6 0.3 3.8 11.3 2.4 5.0 40.8 4.7 2.1 5.4 9.6 1.8 2.1 4.0 5.8 3.2 4.5 15.8 9.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 4.6 14.0 0.1 0.0 0.1 0.6 0.0 0.0 4.7 0.0 0.8 0.0 1.4 5.6 0.0 49.4 0.4 1.9 0.1 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 2.6 0.2 0.0 9.9 1.1 0.3 0.0 0.0 0.1 0.0 0.6 1.0 0.0 1.3 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 7.9 17.4 19.2 0.0 10.5 0.0 3.5 0.0 0.0 23.2 3.9 0.0 0.1 5.5 0.7 2.9 7.7 0.0 5.6 1.8 2.1 2.1 2.5 1.8 2.3 2.0 2.5 2.3 2.1 2.1 2.3 2.5 0.0 1.1 3.6 3.5 4.0 6.3 2.3 14.8 0.1 2.9 7.6 0.6 14.3 1.6 1.8 0.0 1.1 2.9 18.3 17.6 7.4 0.0 0.6 8.1 1.9 6.7 12.0 3.4 13.3 0.5 18.0 1.5 0.3 30.4 1.2 4.6 209.8 21.3 0.0 2.2 14.9 0.0 13.5 4.9 0.2 12.5 8.7 5.4 8.4 8.4 3.6 1.0 5.5 1.0 4.8 28.7 10.5 0.5 2.1 236.8 162.7 0.5 0.3 13.1 37.7 13.8 0.4 0.7 6.0 4.8 1.2 1.2 2.2 25.5 2.7 ZFP36L2 "BRF2, ERF2, RNF162C, TIS11D" ENSG00000152518 "ZFP36 ring finger protein like 2" P47974 2 43222402-43226606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Developmental protein, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1727.3;Basal squamous epithelial cells: 2181.9;Plasma cells: 2029.3;Suprabasal keratinocytes: 1549.6;T-cells: 1760.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047428 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA047428: AB_10963428" "unprognostic (2.07e-2)" "unprognostic (1.81e-2)" "unprognostic (9.77e-2)" "unprognostic (6.10e-2)" "unprognostic (9.66e-2)" "unprognostic (2.36e-1)" "unprognostic (1.41e-1)" "unprognostic (7.62e-3)" "unprognostic (2.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.67e-3)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (2.50e-1)" "unprognostic (4.52e-2)" "unprognostic (1.23e-1)" "unprognostic (2.98e-2)" 187.0 110.8 33.0 150.1 39.9 195.2 175.0 41.0 31.9 141.5 36.9 130.3 113.6 101.7 38.7 103.7 121.1 124.1 97.6 28.5 45.6 64.7 91.4 169.7 171.1 109.1 50.3 187.4 78.7 19.9 37.7 31.7 51.9 123.1 132.5 17.0 92.5 63.8 64.9 219.9 171.2 65.2 58.5 120.7 127.2 19.2 51.5 160.9 180.8 42.1 121.9 93.5 133.7 45.7 36.2 17.4 17.0 9.5 208.0 211.4 6.9 51.7 93.1 21.6 16.4 61.0 16.7 26.0 37.9 59.7 12.0 66.9 18.2 89.9 18.3 46.6 38.0 42.0 6.4 65.1 61.8 92.3 35.0 149.8 143.4 22.1 143.2 32.6 38.9 39.1 42.6 100.1 21.4 192.0 109.4 190.8 26.0 113.2 30.1 81.0 12.7 151.7 36.9 51.5 15.0 37.6 9.8 58.9 32.2 23.2 10.0 150.4 18.6 58.3 25.2 49.7 32.1 84.1 25.1 39.0 19.6 227.7 27.5 18.7 42.5 82.1 46.6 35.3 45.8 18.1 46.1 62.8 51.2 22.7 34.1 33.9 61.6 52.7 28.1 22.0 19.5 30.0 33.0 39.9 41.0 31.9 28.5 45.6 109.1 50.3 51.9 58.5 51.5 45.7 540.1 48.1 67.1 91.1 1144.2 1727.3 1232.0 76.3 2181.9 3.7 455.0 420.5 120.8 420.4 72.4 136.1 0.0 12.2 1167.2 470.8 84.1 37.2 2.4 192.4 241.9 371.7 187.8 340.6 0.4 37.0 22.2 635.9 562.7 292.0 138.5 497.7 185.6 146.8 236.5 0.0 0.6 538.1 26.4 436.2 435.2 12.5 311.9 579.7 302.4 97.4 318.5 214.2 620.0 29.7 13.8 41.1 378.8 259.9 2029.3 590.1 319.2 81.4 48.2 30.5 105.2 631.8 246.5 3.4 27.8 534.9 1549.6 17.0 1760.1 342.5 581.4 238.0 THADA "ARMC13, FLJ21877, GITA, KIAA1767" ENSG00000115970 "THADA armadillo repeat containing" Q6YHU6 2 43230851-43596038 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 74.7;Excitatory neurons: 77.5;Inhibitory neurons: 77.2;Microglial cells: 89.9;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 17.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035191, HPA035192" Uncertain Approved Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA035191: AB_10670290, HPA035192: AB_2674512" "unprognostic (1.20e-1)" "unprognostic (2.95e-1)" "unprognostic (2.07e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (4.26e-1)" "prognostic unfavorable (6.48e-4)" "unprognostic (8.27e-2)" "unprognostic (9.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (4.38e-2)" "unprognostic (1.12e-1)" "unprognostic (3.43e-2)" "unprognostic (5.25e-2)" "unprognostic (2.14e-1)" 11.0 9.3 7.0 7.5 8.3 8.9 11.1 7.1 7.3 12.1 14.8 9.1 4.2 11.0 10.2 9.9 11.1 6.1 9.0 6.9 7.3 9.6 17.3 9.8 14.3 8.3 8.2 11.5 11.5 12.4 11.1 6.1 7.9 13.0 6.1 8.3 10.2 6.9 10.1 13.8 9.4 7.3 7.3 11.7 9.1 10.2 8.1 10.2 13.5 6.1 9.8 10.5 11.0 9.3 19.2 22.6 10.0 0.3 26.6 22.8 14.4 12.6 10.3 11.6 9.8 13.3 11.3 17.5 21.0 15.0 15.8 17.4 15.7 21.6 19.9 14.6 15.5 12.5 8.6 17.7 9.3 19.5 9.7 15.0 19.1 24.5 31.8 12.2 16.1 6.5 22.6 9.1 14.2 24.2 19.4 21.7 20.2 27.4 12.7 8.9 18.1 13.3 18.4 16.9 13.2 20.5 11.9 11.5 11.3 11.6 11.8 10.1 13.6 19.0 14.0 14.7 22.9 23.0 15.2 19.6 15.4 19.1 15.7 17.2 2.6 1.2 3.4 4.0 3.7 3.6 3.7 4.2 4.2 3.6 3.4 4.0 1.8 5.4 2.9 3.2 4.5 2.2 7.0 8.3 7.1 7.3 6.9 7.3 8.3 8.2 7.9 7.3 8.1 9.3 11.7 19.2 14.4 74.7 15.4 8.5 16.5 8.9 23.3 11.9 11.8 11.0 8.5 18.6 12.0 14.7 16.7 7.9 9.6 5.1 1.9 8.8 20.9 19.5 17.0 10.3 7.3 12.4 77.5 9.6 5.4 12.5 15.3 11.2 6.3 19.7 11.4 17.8 9.7 3.3 77.2 5.4 4.1 9.7 7.4 11.1 9.9 12.9 3.6 89.9 7.9 5.3 10.3 73.9 111.0 6.4 7.2 8.6 11.5 11.3 2.5 7.4 22.6 24.9 0.0 16.2 9.1 20.7 14.1 11.0 4.4 4.8 16.5 20.3 6.3 7.4 PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Endometrial stromal cells: 150.5;Oligodendrocyte precursor cells: 191.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.4;RPTEC TERT1: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: AB_2686828" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (4.27e-3)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" 13.1 3.0 2.8 1.7 2.7 0.1 8.9 3.6 2.8 20.9 8.8 11.8 3.7 19.8 4.4 4.6 15.9 7.3 4.8 2.3 2.8 15.9 1.7 27.6 2.9 3.0 3.4 23.0 2.9 5.4 2.0 3.8 3.1 5.1 4.3 1.7 4.8 5.0 1.8 8.4 6.5 9.8 2.7 5.4 5.0 3.9 2.7 0.4 5.5 2.5 1.8 6.2 8.5 2.5 0.5 4.0 1.6 0.0 3.1 7.4 0.3 0.5 2.0 0.8 2.0 0.0 1.3 1.0 0.2 0.6 3.3 2.6 0.5 0.6 1.5 0.0 1.1 0.1 0.6 0.1 0.5 0.0 0.5 2.2 0.6 1.9 0.1 1.1 1.7 1.6 3.9 0.1 0.7 1.1 0.8 0.1 0.9 0.6 3.9 0.0 4.6 0.0 6.3 0.2 1.2 0.6 0.4 0.0 3.9 1.1 0.5 0.1 0.2 4.5 1.3 0.2 1.4 0.9 0.2 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 2.7 3.6 2.8 2.3 2.8 3.0 3.4 3.1 2.7 2.7 2.5 4.6 38.5 8.7 19.2 0.9 8.7 17.5 5.8 6.8 1.0 5.3 8.3 2.9 11.5 12.9 66.2 6.2 0.3 1.3 0.1 5.9 6.2 1.6 5.9 150.5 3.8 0.0 0.0 15.6 1.4 0.3 57.4 3.1 8.8 1.3 42.6 2.2 0.0 0.8 0.0 4.3 0.3 2.0 0.3 8.6 3.3 35.8 1.2 12.4 15.9 0.2 5.8 0.0 191.0 52.7 7.2 0.0 50.4 0.4 9.2 0.3 4.1 7.3 4.1 46.0 40.7 24.6 10.8 5.9 2.6 8.4 0.5 3.6 13.1 0.6 8.7 C1GALT1C1L ENSG00000223658 "C1GALT1 specific chaperone 1 like" P0DN25 2 43675151-43676429 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 7.0;Muller glia cells: 5.1;Spermatocytes: 18.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 13.1;U-2 OS: 8.2" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.18e-1)" "unprognostic (3.71e-2)" "unprognostic (2.50e-2)" "unprognostic (1.02e-2)" "unprognostic (2.32e-1)" "unprognostic (5.71e-3)" "unprognostic (2.19e-3)" "unprognostic (4.91e-2)" "unprognostic (2.78e-2)" "unprognostic (2.71e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (7.73e-2)" "unprognostic (3.81e-3)" "unprognostic (8.88e-2)" "unprognostic (1.39e-2)" "unprognostic (8.86e-2)" 1.7 1.8 0.7 0.4 1.0 0.0 2.0 1.0 1.1 2.1 0.8 2.3 0.3 4.0 6.0 0.3 1.1 0.6 2.3 0.7 0.9 1.8 0.1 0.3 0.2 0.9 1.0 1.1 1.0 2.0 0.7 0.9 0.9 1.5 0.7 3.9 1.2 2.4 0.5 0.5 0.5 3.2 0.9 0.3 0.5 5.8 0.9 0.2 1.2 0.8 0.3 1.0 0.7 1.0 0.0 0.3 0.0 0.0 2.4 1.2 0.1 0.2 0.4 0.8 1.0 0.5 3.8 0.0 3.7 0.3 3.3 0.3 0.0 0.2 2.0 0.0 2.9 1.7 1.1 0.8 0.8 0.0 0.0 1.6 0.6 2.5 0.1 1.3 2.6 0.0 2.0 0.0 0.2 4.0 0.0 3.7 0.0 0.0 0.0 0.0 1.4 0.0 3.2 0.8 0.1 13.1 0.0 0.2 2.7 0.3 0.9 2.7 0.0 3.3 8.2 0.2 0.8 0.0 2.0 0.0 2.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 1.0 1.1 0.7 0.9 0.9 1.0 0.9 0.9 0.9 1.0 0.9 0.0 0.5 0.0 0.0 0.0 0.5 0.0 1.8 1.0 0.5 1.0 0.5 2.8 0.6 0.0 0.0 0.3 0.1 0.0 0.0 1.3 2.8 1.0 7.0 0.5 0.0 0.0 0.0 0.6 0.3 2.4 0.0 0.3 0.0 1.6 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.8 2.5 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.1 0.1 0.2 1.5 3.7 0.0 1.9 2.1 18.8 2.4 0.2 0.0 0.1 0.0 2.2 0.3 0.1 DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 197.5;Respiratory ciliated cells: 133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 110.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062905 Approved Supported Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA062905: AB_2684899" "unprognostic (3.46e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-2)" "unprognostic (2.89e-2)" "unprognostic (4.05e-2)" "unprognostic (1.84e-3)" "unprognostic (9.85e-2)" "unprognostic (2.87e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.73e-5)" "unprognostic (1.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.32e-2)" "unprognostic (4.60e-2)" 16.2 23.2 20.2 7.5 21.3 6.8 32.6 16.1 23.6 28.3 34.9 15.4 19.0 35.6 46.6 11.0 53.4 20.7 15.5 20.0 21.9 50.2 13.4 23.4 10.2 20.4 19.3 39.7 16.2 42.2 31.2 13.6 18.7 20.8 17.9 44.0 16.3 20.0 10.2 15.8 16.3 19.8 17.9 11.0 17.1 44.9 21.3 10.8 34.3 8.5 9.7 15.0 13.9 20.6 21.2 12.0 20.5 13.1 32.5 64.5 17.6 11.5 24.8 13.3 12.4 4.0 14.4 12.0 24.8 15.2 17.0 13.8 9.9 16.5 15.4 15.4 21.1 9.4 5.5 15.3 31.3 18.7 14.8 38.3 23.4 26.5 12.1 40.6 18.5 14.1 29.0 5.6 18.7 10.8 9.2 20.6 9.4 27.3 12.0 12.2 19.0 3.8 110.1 18.0 14.0 25.1 13.0 7.1 15.5 19.4 19.7 16.9 13.1 11.6 10.5 14.4 9.8 21.0 12.3 3.0 25.8 4.7 12.6 14.8 2.3 2.1 1.7 3.9 1.8 3.7 2.2 2.4 3.1 2.1 2.7 2.3 0.8 2.6 3.1 1.8 1.4 1.4 20.2 21.3 16.1 23.6 20.0 21.9 20.4 19.3 18.7 17.9 21.3 20.6 11.9 19.2 16.8 58.1 6.4 9.7 18.2 42.9 7.4 21.7 19.3 22.4 13.9 21.5 31.3 53.3 29.2 19.7 2.3 10.2 90.1 21.7 197.5 71.7 42.2 8.1 12.7 5.5 96.8 22.0 9.1 27.8 15.3 24.2 17.7 26.2 14.6 7.3 12.4 16.8 64.9 20.3 50.8 4.5 5.3 39.4 33.2 5.9 23.2 22.5 3.3 29.3 4.1 33.7 43.4 14.5 32.1 33.8 4.7 9.6 52.4 84.1 133.8 36.9 19.7 14.8 14.8 102.1 15.9 9.1 9.1 9.3 4.9 30.1 17.5 12.8 ABCG5 STSL ENSG00000138075 "ATP binding cassette subfamily G member 5" Q9H222 2 43812472-43838865 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 69 "intestine: 47.8;liver: 62.0" "Group enriched" "Detected in some" 6 "Hepatocytes: 60.3;Paneth cells: 23.9;Proximal enterocytes: 30.9" "Cancer enriched" "Detected in some" 23 "liver cancer: 11.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 54 "Hep G2: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.71e-1)" "unprognostic (5.47e-2)" "unprognostic (4.01e-1)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "unprognostic (9.97e-2)" "prognostic favorable (2.60e-5)" "unprognostic (4.59e-2)" "unprognostic (3.10e-1)" "unprognostic (1.38e-3)" "unprognostic (3.07e-4)" "unprognostic (1.86e-1)" "unprognostic (3.07e-1)" "unprognostic (5.52e-3)" "unprognostic (8.29e-2)" "unprognostic (5.31e-2)" "unprognostic (3.08e-2)" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 47.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 62.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.6 5.7 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.0 0.1 0.6 0.1 0.0 0.0 5.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.7 60.3 0.0 0.0 3.2 2.5 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 1.8 0.0 23.9 0.0 0.0 0.0 30.9 0.0 0.0 0.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.7 0.0 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43995989 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced Mitochondria No No 210000 "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB033786: AB_2137450, HPA036408: AB_10670438, HPA036409: AB_2675108" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.61e-3)" "prognostic unfavorable (1.72e-5)" "unprognostic (1.68e-1)" "unprognostic (8.34e-3)" "prognostic unfavorable (2.31e-7)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-3)" "unprognostic (7.68e-2)" "prognostic favorable (6.65e-6)" "unprognostic (9.07e-2)" "unprognostic (1.92e-1)" "unprognostic (1.12e-1)" "unprognostic (5.00e-2)" 32.2 33.2 30.1 23.8 31.3 49.6 41.6 39.3 35.4 23.9 49.2 50.6 33.4 32.5 28.4 28.4 27.6 18.2 47.0 30.8 31.8 63.5 48.3 19.6 31.2 33.0 30.4 34.1 30.4 48.7 19.2 27.2 35.2 27.7 48.9 40.4 27.8 25.3 100.9 30.2 30.3 27.6 30.2 24.3 27.1 33.2 32.1 29.3 31.2 93.5 31.7 27.0 22.5 36.3 127.8 101.9 62.3 80.0 58.1 79.9 108.0 82.7 59.4 88.0 67.3 164.4 65.7 181.7 78.4 50.8 58.8 105.2 118.8 86.3 116.8 110.2 75.2 164.2 76.5 217.9 85.5 239.9 71.4 77.3 73.8 81.6 130.4 49.2 71.2 53.6 246.5 71.5 75.8 68.5 126.8 273.7 104.0 123.8 71.8 139.7 140.7 147.6 95.3 115.3 111.0 107.3 93.6 120.6 154.5 79.2 90.1 140.6 62.6 63.2 86.4 66.9 89.2 72.5 87.4 156.2 60.0 144.1 55.6 10.5 16.5 2.9 13.3 16.2 25.5 22.5 18.0 17.9 23.5 24.5 24.8 21.9 1.2 20.3 18.9 9.6 16.3 20.2 30.1 31.3 39.3 35.4 30.8 31.8 33.0 30.4 35.2 30.2 32.1 36.3 29.2 22.4 34.1 56.8 46.2 46.3 27.2 34.6 46.1 66.4 37.6 30.4 97.2 32.9 35.4 46.0 31.3 37.1 22.5 33.1 21.5 25.6 5.3 31.2 48.2 30.4 27.5 58.4 91.6 17.7 23.6 32.4 40.2 40.1 29.2 51.0 22.1 55.1 25.2 65.6 96.5 49.2 20.3 38.8 25.9 6.3 25.1 28.9 21.4 38.4 36.8 24.5 23.7 55.3 94.9 20.0 33.0 23.7 34.4 31.9 36.6 62.3 25.8 57.0 13.1 45.8 32.6 27.2 33.3 53.9 44.3 33.2 32.2 63.7 76.0 31.9 PPM1B "PP2CB, PP2CBETA, PPC2BETAX" ENSG00000138032 "Protein phosphatase, Mg2+/Mn2+ dependent 1B" O75688 2 44167969-44244384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 218.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016745 Approved Approved Nucleoli,Cytosol NA NA 75000 "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoli, Cytosol" "HPA016745: AB_1855622" "unprognostic (5.49e-2)" "unprognostic (2.67e-2)" "unprognostic (1.11e-2)" "unprognostic (2.96e-3)" "unprognostic (1.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.58e-1)" "unprognostic (1.94e-1)" "unprognostic (2.25e-1)" "unprognostic (6.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (1.75e-2)" 40.2 20.4 41.2 19.5 48.0 44.0 23.9 45.1 61.8 23.0 43.1 28.6 20.3 23.9 30.0 22.5 21.2 21.8 33.3 38.6 42.1 29.0 44.0 21.9 28.7 41.4 44.1 22.9 32.4 35.8 18.9 18.8 42.1 30.6 28.7 49.9 27.0 23.3 129.4 20.5 21.7 22.8 40.2 26.4 23.1 21.4 42.7 36.0 22.8 86.5 27.0 24.7 21.4 50.9 37.1 32.8 41.8 31.2 51.3 23.8 47.6 27.9 32.0 28.2 24.8 43.8 23.3 40.7 42.4 32.4 23.0 19.6 47.6 18.2 41.6 41.7 18.4 42.9 19.9 30.8 41.4 38.6 34.1 23.0 31.5 22.5 37.9 22.2 23.5 18.4 31.7 41.5 25.7 30.6 38.6 61.5 52.4 33.4 11.0 40.5 46.6 27.1 66.3 36.9 33.7 42.5 25.3 37.4 33.5 62.3 20.2 26.7 21.6 24.7 35.5 20.6 27.8 36.2 25.5 37.7 13.4 63.2 18.3 6.9 2.2 8.1 4.6 3.0 3.9 4.2 4.3 3.9 3.7 4.5 5.8 4.0 6.1 3.2 3.6 3.6 4.3 1.1 41.2 48.0 45.1 61.8 38.6 42.1 41.4 44.1 42.1 40.2 42.7 50.9 17.4 19.2 20.8 78.4 49.3 60.5 40.3 14.4 35.3 51.9 31.8 19.9 55.4 38.6 24.0 40.5 64.6 31.5 68.6 64.5 46.9 42.5 68.5 44.1 33.3 22.0 40.2 32.8 95.9 46.4 29.7 33.7 35.2 62.4 26.6 27.4 20.3 55.0 26.8 107.7 91.8 31.5 30.5 55.2 63.0 43.0 35.8 45.0 56.9 38.4 46.7 57.5 51.5 112.6 218.0 44.7 46.6 33.8 51.9 71.2 26.8 41.0 16.9 147.5 26.3 33.5 32.4 48.5 27.7 36.6 62.4 64.6 63.8 29.5 37.3 88.7 SLC3A1 "ATR1, CSNU1, D2H, NBAT, RBAT" ENSG00000138079 "Solute carrier family 3 member 1" Q07837 2 44275458-44321494 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cystinuria, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 136.2;kidney: 649.3;pancreas: 217.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 74.4;Glandular and luminal cells: 128.9;Proximal enterocytes: 258.9;Proximal tubular cells: 363.0" "Cancer enriched" "Detected in many" 7 "renal cancer: 61.9" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 106.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038360, HPA071102" Enhanced Approved "Nuclear bodies,Mitochondria" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Nuclear bodies" "HPA038360: AB_2675975, HPA071102: AB_2732171" "unprognostic (1.67e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (6.14e-2)" "unprognostic (9.45e-2)" "unprognostic (2.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.90e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "prognostic favorable (3.67e-7)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (3.77e-1)" "unprognostic (1.58e-4)" 0.5 0.3 1.2 1.1 1.7 0.6 0.4 6.8 3.4 1.0 0.1 22.4 113.9 1.4 1.9 0.2 0.6 51.5 0.4 1.6 1.3 649.3 36.6 0.4 0.4 0.6 0.6 0.5 217.5 0.0 0.5 0.1 0.7 1.0 22.7 3.5 0.3 0.3 1.0 0.6 136.2 0.5 0.0 0.5 0.9 1.7 1.0 0.0 0.4 0.1 0.1 0.3 0.3 1.7 0.0 1.0 0.0 0.2 0.2 0.1 0.3 0.1 0.0 0.0 0.1 4.9 0.0 0.1 4.3 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.4 0.1 1.2 0.5 0.1 0.1 0.2 106.1 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.2 0.1 0.4 0.2 0.3 0.1 0.3 0.2 0.4 0.3 0.3 0.7 0.3 0.4 0.5 0.6 0.3 0.1 1.0 0.6 0.7 0.4 0.4 0.1 0.3 0.2 0.1 1.2 1.7 6.8 3.4 1.6 1.3 0.6 0.6 0.7 0.0 1.0 1.7 0.2 3.2 1.5 0.3 6.1 0.0 0.3 0.0 0.0 12.1 0.2 0.0 0.4 74.4 0.0 42.3 10.4 0.1 0.8 18.2 62.6 37.0 12.4 62.2 14.4 0.6 0.0 0.0 9.1 13.8 0.0 0.9 1.1 128.9 0.0 0.1 0.4 4.6 0.1 21.9 9.0 8.4 0.0 0.0 0.0 8.5 1.2 3.2 0.0 1.0 1.6 1.0 1.0 3.0 3.7 4.8 18.6 0.4 1.5 1.1 258.9 363.0 0.0 11.2 0.0 2.6 1.2 0.8 0.4 0.7 0.1 0.1 2.8 0.2 15.7 1.2 PREPL KIAA0436 ENSG00000138078 "Prolyl endopeptidase like" Q4J6C6 2 44316281-44361862 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 243.1;Inhibitory neurons: 219.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063238 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA063238: AB_2684967" "unprognostic (5.60e-3)" "unprognostic (9.81e-2)" "unprognostic (4.51e-2)" "unprognostic (4.65e-3)" "unprognostic (2.22e-1)" "unprognostic (8.53e-2)" "unprognostic (5.98e-3)" "unprognostic (4.38e-3)" "unprognostic (2.27e-1)" "unprognostic (2.72e-2)" "unprognostic (1.52e-2)" "unprognostic (4.67e-2)" "unprognostic (2.33e-2)" "unprognostic (3.79e-1)" "unprognostic (1.87e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-1)" 26.2 50.9 64.6 18.4 67.4 5.5 31.9 42.9 133.1 35.9 27.5 24.4 26.1 47.2 70.9 22.9 33.6 28.4 62.7 73.1 93.1 62.5 21.6 24.5 17.4 45.3 26.0 49.8 25.2 54.4 52.5 21.4 41.7 37.3 29.4 123.8 26.2 33.1 34.3 22.3 27.9 34.1 34.0 23.1 26.4 28.2 53.4 19.1 61.3 51.3 17.9 23.6 23.9 58.4 41.2 31.7 35.3 45.3 55.7 58.0 26.8 45.1 34.6 32.0 27.4 34.1 28.4 52.3 61.2 47.5 36.6 34.6 50.6 33.0 61.0 48.7 36.2 35.5 24.2 26.3 40.0 35.8 32.5 37.9 64.6 61.8 50.1 62.9 31.4 24.3 45.6 72.6 43.6 22.2 39.1 17.4 33.4 52.8 35.1 30.1 42.8 38.0 61.4 24.0 58.3 46.5 28.9 30.6 67.4 33.9 41.4 27.6 32.8 56.3 32.1 44.6 31.0 40.2 28.2 34.3 65.9 40.1 42.5 6.9 4.4 3.5 7.9 4.9 11.2 8.5 7.3 8.5 6.3 7.0 10.7 8.7 1.3 11.1 4.3 2.9 8.8 5.8 64.6 67.4 42.9 133.1 73.1 93.1 45.3 26.0 41.7 34.0 53.4 58.4 16.3 32.1 37.4 83.2 34.0 13.0 16.0 13.2 21.6 89.1 33.4 26.7 88.1 32.9 21.1 64.4 47.9 8.7 30.0 20.4 39.2 17.4 21.1 40.1 36.7 18.7 33.0 13.9 243.1 23.6 4.9 29.5 28.1 32.1 13.3 21.9 16.8 32.8 11.6 144.7 219.9 24.2 18.3 13.5 7.5 10.0 35.4 14.2 17.8 55.3 12.8 41.4 32.0 81.4 126.2 13.6 20.8 33.1 21.8 16.3 12.2 38.8 35.5 63.2 19.7 44.5 27.2 29.2 28.7 16.3 14.8 8.8 29.1 26.0 17.1 10.7 CAMKMT "C2orf34, CLNMT" ENSG00000143919 "Calmodulin-lysine N-methyltransferase" Q7Z624 2 44361947-44772592 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 155.1;Excitatory neurons: 88.7;Inhibitory neurons: 93.7;Microglial cells: 114.3;Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067912 Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA067912: AB_2685922" "unprognostic (2.28e-1)" "unprognostic (6.15e-2)" "unprognostic (1.96e-1)" "unprognostic (2.39e-2)" "prognostic favorable (9.10e-4)" "unprognostic (1.03e-1)" "unprognostic (9.58e-3)" "unprognostic (1.46e-3)" "unprognostic (1.85e-1)" "unprognostic (7.42e-2)" "unprognostic (8.76e-2)" "unprognostic (1.37e-1)" "unprognostic (3.33e-1)" "unprognostic (4.82e-2)" "unprognostic (4.66e-2)" "unprognostic (1.70e-1)" "unprognostic (8.57e-2)" 4.2 5.3 15.9 3.9 21.1 10.2 5.3 19.4 21.1 5.9 17.8 7.0 5.3 4.1 6.5 6.1 4.9 5.7 5.0 15.5 17.1 7.5 4.8 3.9 5.4 17.7 16.4 3.9 9.8 9.8 5.6 3.3 17.3 3.5 6.8 8.5 4.8 3.9 7.8 5.8 5.7 3.9 15.5 3.7 5.8 13.2 17.9 6.2 7.3 3.3 5.4 4.5 4.7 20.4 10.2 6.2 7.4 6.8 8.0 8.1 15.0 7.4 6.0 4.3 5.5 11.9 9.0 9.6 8.6 5.6 5.3 8.3 10.6 13.2 7.6 35.2 13.3 14.2 12.1 22.4 3.1 9.4 9.5 2.6 8.0 5.9 10.9 6.1 6.4 9.9 10.4 17.1 7.1 10.9 17.6 19.1 13.9 24.6 6.1 10.3 8.3 19.4 20.8 11.6 14.0 13.4 7.6 24.1 9.2 7.0 8.8 7.7 7.6 5.5 6.4 6.1 5.9 13.3 11.5 18.2 6.1 16.5 3.9 13.1 8.2 6.2 11.1 6.9 11.5 20.9 11.2 9.7 9.7 14.7 16.9 13.4 5.2 8.7 8.4 10.1 18.3 6.9 15.9 21.1 19.4 21.1 15.5 17.1 17.7 16.4 17.3 15.5 17.9 20.4 5.4 6.4 3.1 155.1 11.0 5.2 7.9 10.9 9.1 5.3 6.6 5.2 2.2 10.0 5.5 9.2 0.0 3.3 6.9 4.5 23.5 13.3 74.3 8.2 7.2 4.0 0.0 13.3 88.7 15.6 4.5 6.2 11.7 10.0 5.7 2.0 3.3 6.3 5.8 1.7 93.7 5.5 20.3 1.9 4.9 39.0 8.1 4.3 10.6 114.3 6.4 20.3 13.4 121.2 211.7 8.6 8.3 5.7 13.3 5.8 7.2 14.5 7.4 3.0 0.0 3.6 5.0 35.5 5.8 10.7 7.4 2.6 9.2 7.9 8.1 6.0 SIX3 HPE2 ENSG00000138083 "SIX homeobox 3" O95343 2 44941702-44946071 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 22.7;choroid plexus: 12.2;parathyroid gland: 9.1;pituitary gland: 27.8;retina: 25.3" "Group enriched" "Detected in some" 14 "Bipolar cells: 203.9;Horizontal cells: 185.1;Muller glia cells: 392.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "hTERT-RPE1: 68.7;SCLC-21H: 63.1;SH-SY5Y: 25.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 38.7;hypothalamus: 19.5" HPA067988 Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067988: AB_2685939" "unprognostic (1.19e-3)" "unprognostic (1.05e-2)" "unprognostic (4.76e-1)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (1.76e-2)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (1.44e-1)" "unprognostic (6.82e-2)" "unprognostic (1.22e-1)" "unprognostic (2.49e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (2.73e-2)" 0.0 0.0 8.3 0.0 22.7 0.0 0.1 0.8 16.4 0.7 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 18.2 0.1 0.0 0.0 0.1 0.5 4.5 0.0 0.6 9.1 27.8 0.0 0.5 0.0 0.0 25.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 1.8 10.9 0.0 0.0 0.1 0.0 0.0 0.2 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.6 0.0 11.7 0.0 0.0 0.6 5.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 68.7 0.0 1.4 0.0 0.0 0.0 0.0 0.4 2.7 0.4 0.0 0.3 0.0 0.4 0.0 0.0 0.0 63.1 25.2 0.1 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.1 0.2 0.2 0.2 0.3 0.4 0.4 0.5 0.2 0.3 0.1 8.3 22.7 0.8 16.4 1.8 18.2 0.5 4.5 0.5 0.2 10.9 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 203.9 1.1 1.3 0.7 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 11.2 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.1 0.1 0.2 0.0 0.0 0.3 2.7 0.0 0.1 0.0 0.0 0.0 392.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.2 18.3 0.0 0.5 0.4 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SIX2 ENSG00000170577 "SIX homeobox 2" Q9NPC8 2 45005182-45009452 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 21.1;skeletal muscle: 33.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 6.1;Cardiomyocytes: 3.3;Fibroblasts: 3.0;Ionocytes: 8.2;Skeletal myocytes: 8.5;Smooth muscle cells: 3.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.8;LHCN-M2: 46.8;RH-30: 31.9;SCLC-21H: 54.3;U-2197: 35.3;U-698: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA056958 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear membrane" "HPA056958: AB_2683287" "unprognostic (1.14e-3)" "unprognostic (2.73e-2)" "unprognostic (3.09e-6)" "unprognostic (1.28e-2)" "unprognostic (3.28e-1)" "unprognostic (8.77e-2)" "unprognostic (4.06e-3)" "unprognostic (9.17e-2)" "unprognostic (1.48e-1)" "unprognostic (1.96e-1)" "unprognostic (1.02e-2)" "unprognostic (1.07e-2)" "unprognostic (4.53e-9)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-5)" "unprognostic (1.05e-1)" 10.4 0.1 0.1 0.1 0.3 0.0 1.6 0.2 0.5 11.6 0.5 0.7 0.0 1.7 0.1 0.2 0.2 0.0 1.5 0.9 0.2 0.5 0.0 0.2 0.1 0.4 1.5 0.1 6.0 2.1 12.9 0.1 1.7 6.2 0.0 0.9 21.1 1.2 33.8 0.4 0.1 0.1 0.1 0.0 9.5 0.3 0.2 3.9 0.6 15.5 0.0 1.8 8.6 0.2 0.7 0.0 0.0 4.2 13.0 48.8 0.0 0.2 2.3 1.0 0.1 0.4 0.0 0.0 2.2 0.0 0.4 0.1 4.7 8.5 0.6 0.0 2.5 0.0 16.7 0.0 0.0 0.0 4.5 2.4 0.1 10.4 0.1 0.4 1.6 0.5 0.2 0.0 46.8 1.7 0.0 2.8 0.4 0.0 10.2 0.0 31.9 0.0 0.1 2.7 54.3 0.4 7.1 0.2 0.0 0.5 0.4 4.2 0.7 0.9 2.7 35.3 0.0 1.0 0.0 43.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.5 0.9 0.2 0.4 1.5 1.7 0.1 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.9 0.4 6.1 0.0 0.0 1.2 0.6 3.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.4 0.0 0.0 0.0 2.2 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 1.2 0.0 0.0 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.5 0.0 8.5 3.2 0.0 0.4 0.0 0.9 0.0 0.0 0.2 0.0 0.2 SRBD1 FLJ10379 ENSG00000068784 "S1 RNA binding domain 1" Q8N5C6 2 45388680-45612165 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030567, HPA030568" Approved Approved Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Mitochondria, Cytosol" "HPA030567: AB_10611244, HPA030568: AB_10601856" "unprognostic (1.16e-2)" "unprognostic (1.27e-1)" "unprognostic (4.97e-3)" "unprognostic (2.46e-1)" "unprognostic (8.20e-3)" "unprognostic (4.14e-1)" "unprognostic (8.69e-3)" "unprognostic (9.74e-2)" "unprognostic (7.11e-2)" "unprognostic (9.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.76e-1)" "unprognostic (3.42e-3)" "unprognostic (3.99e-1)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (2.29e-1)" 6.8 5.6 1.9 7.2 2.5 6.5 7.6 2.1 1.9 9.8 3.5 7.1 5.7 7.2 11.8 4.7 5.4 5.6 5.8 1.7 2.5 7.6 8.7 6.5 7.5 2.5 2.3 5.4 7.3 12.2 3.7 6.8 2.8 7.4 8.0 3.7 5.2 5.7 3.1 3.8 5.4 6.8 2.4 8.6 8.1 9.0 2.5 11.5 10.2 4.9 7.5 5.3 3.9 2.8 18.7 9.5 19.1 12.9 6.9 15.0 15.1 14.1 12.2 13.2 12.1 8.0 7.8 16.1 10.2 10.1 9.8 8.7 19.0 17.9 24.3 22.1 10.6 21.4 7.4 17.3 8.1 17.9 12.1 9.3 7.2 15.7 18.2 5.8 16.2 5.8 15.6 11.9 19.8 17.0 24.3 13.8 21.9 12.0 10.3 16.5 27.5 14.7 15.0 12.1 16.8 13.7 12.3 13.1 14.0 9.9 8.2 6.4 14.9 18.4 14.7 9.0 12.3 12.5 4.9 9.6 10.4 17.6 13.5 3.9 6.2 13.1 5.4 7.0 4.8 5.3 4.0 6.3 6.1 4.6 5.4 5.0 2.3 8.3 12.3 5.7 4.5 4.3 1.9 2.5 2.1 1.9 1.7 2.5 2.5 2.3 2.8 2.4 2.5 2.8 10.9 19.2 7.7 28.7 13.0 3.6 3.5 6.2 8.6 7.9 8.7 8.0 8.8 8.6 10.6 3.7 4.2 8.4 15.7 5.9 9.8 8.3 3.5 11.5 20.7 9.3 7.2 15.8 22.0 9.1 7.1 10.9 20.9 9.9 8.2 11.0 7.9 13.8 9.6 13.5 32.7 9.7 0.0 22.5 3.9 2.5 7.5 13.8 7.2 46.9 13.7 12.9 13.4 48.2 51.8 4.6 6.3 6.4 19.8 2.9 5.9 10.8 7.8 14.7 13.1 12.9 10.2 37.5 28.4 9.5 3.8 5.6 12.8 16.6 5.1 2.2 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 412.0;placenta: 445.6" "Cell type enhanced" "Detected in many" "Adipocytes: 831.5;Endothelial cells: 425.8;Hepatic stellate cells: 538.7;Syncytiotrophoblasts: 349.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.6;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.6" "Cell line enhanced" "Detected in many" "BEWO: 267.3;BJ hTERT+: 266.7;HHSteC: 326.3;RT4: 339.8;TIME: 337.8;U-138 MG: 284.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031200, HPA069697" Supported Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Cytosol "HPA031200: AB_2673785, HPA069697: AB_2732139" "unprognostic (1.74e-1)" "unprognostic (9.47e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.75e-1)" "unprognostic (2.22e-2)" "unprognostic (8.67e-2)" "unprognostic (6.00e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-2)" "unprognostic (9.29e-2)" "prognostic favorable (2.63e-4)" "unprognostic (6.66e-3)" "unprognostic (7.75e-2)" "unprognostic (7.56e-2)" "unprognostic (1.36e-1)" 296.0 52.1 53.4 66.1 48.6 2.3 166.7 44.6 47.7 72.9 139.1 57.1 46.3 87.9 26.0 72.7 80.1 83.2 122.1 39.2 44.7 89.5 110.1 412.0 47.9 60.5 54.2 34.5 59.6 79.4 25.9 445.6 60.2 51.8 42.6 53.6 40.0 66.3 80.5 42.9 50.9 71.7 45.6 84.6 42.8 20.0 75.4 17.9 138.1 153.6 40.3 94.9 47.8 44.6 32.2 33.5 2.1 2.5 153.8 98.6 267.3 98.7 266.7 55.6 60.1 5.8 5.5 0.1 23.8 188.5 55.2 15.2 0.6 79.0 41.3 0.9 1.6 0.0 10.3 71.8 326.3 0.1 19.8 145.0 106.9 108.7 75.8 41.0 193.1 0.7 3.1 0.2 34.2 27.8 0.9 0.8 1.3 22.4 18.5 1.0 3.7 10.5 34.5 339.8 1.4 68.5 77.4 175.5 21.0 68.3 11.7 14.1 337.8 284.0 8.1 38.3 8.4 0.2 0.2 0.1 207.4 5.4 7.4 20.6 0.1 8.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.1 0.1 53.4 48.6 44.6 47.7 39.2 44.7 60.5 54.2 60.2 45.6 75.4 44.6 831.5 76.9 151.7 28.4 4.1 48.2 69.8 108.6 43.9 4.5 27.4 29.5 79.2 32.9 124.9 3.7 10.4 126.2 6.6 112.6 1.9 23.0 12.9 36.1 32.7 425.8 4.2 18.7 1.2 52.4 299.9 76.8 32.1 67.6 41.2 2.3 538.7 78.0 55.5 0.0 1.6 13.9 22.4 60.9 30.3 52.7 12.5 21.4 28.4 155.5 0.6 95.5 0.0 31.2 1.3 26.1 53.7 6.4 3.9 57.8 45.9 30.2 31.7 59.3 282.7 23.3 250.5 1.5 4.6 65.0 33.2 349.7 15.9 4.7 23.6 85.7 TMEM247 ENSG00000284701 "Transmembrane protein 247" A6NEH6 2 46479565-46484425 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 21.8" "Group enriched" "Detected in some" 12 "Early spermatids: 443.1;Late spermatids: 400.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 24 "U-266/84: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079482 Enhanced NA NA "Cluster 16: U-266 - Nucleosome" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA079482: " 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 443.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 400.3 3.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.0 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ATP6V1E2 "ATP6E1, ATP6EL2, ATP6V1EL2, MGC9341, VMA4" ENSG00000250565 "ATPase H+ transporting V1 subunit E2" Q96A05 2 46490750-46542577 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 28.4" "Group enriched" "Detected in many" 10 "Early spermatids: 350.9;Late spermatids: 196.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 19.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA075092 Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA075092: " "unprognostic (1.62e-1)" "unprognostic (9.65e-3)" "unprognostic (4.31e-2)" "unprognostic (4.39e-3)" "unprognostic (1.02e-1)" "unprognostic (1.52e-2)" "unprognostic (4.52e-3)" "unprognostic (8.56e-2)" "unprognostic (2.98e-1)" "unprognostic (5.44e-2)" "unprognostic (1.51e-1)" "unprognostic (1.58e-1)" "unprognostic (2.19e-1)" "unprognostic (1.43e-1)" "unprognostic (1.98e-1)" "unprognostic (8.07e-2)" "unprognostic (9.32e-2)" 1.8 2.3 4.1 1.4 4.2 0.9 2.1 3.6 4.4 1.5 3.1 1.7 0.4 1.5 6.4 1.2 1.4 0.7 1.6 3.8 3.7 2.1 1.9 1.2 1.7 4.0 3.8 1.7 2.8 1.7 2.8 1.1 4.0 2.9 0.7 2.4 2.4 1.6 3.4 2.9 1.4 0.8 4.0 2.0 1.6 28.4 3.8 1.2 1.4 1.4 1.6 1.8 1.6 4.0 8.6 5.5 1.8 4.2 1.7 3.1 0.9 2.9 1.1 1.3 0.6 1.7 1.4 5.1 5.2 2.8 4.2 2.0 4.2 2.1 2.8 7.8 3.3 1.2 1.0 1.2 1.9 2.2 2.4 2.6 19.2 1.8 4.0 1.5 1.3 5.4 3.6 8.8 0.9 5.6 1.5 6.6 3.5 4.4 4.6 3.7 4.4 6.4 2.6 1.9 4.8 10.3 1.9 2.0 4.3 3.0 1.3 1.0 1.3 1.4 5.1 2.5 2.1 4.3 3.7 5.3 2.0 6.6 2.3 0.0 0.8 0.2 0.8 0.4 1.1 0.8 1.5 1.6 0.7 1.0 1.1 1.6 0.5 0.3 0.5 1.7 1.0 0.5 4.1 4.2 3.6 4.4 3.8 3.7 4.0 3.8 4.0 4.0 3.8 4.0 4.7 3.2 0.5 5.5 12.9 5.7 11.3 1.7 8.6 11.8 14.8 18.5 6.7 5.7 2.4 3.7 12.5 2.9 4.0 2.5 9.8 3.3 350.9 3.8 7.8 3.1 3.5 2.5 7.2 3.3 2.2 9.8 5.1 3.9 0.0 5.0 5.0 2.7 2.2 18.5 6.8 2.1 0.0 7.7 5.1 196.3 9.9 5.9 5.4 1.0 7.0 16.5 6.2 4.5 7.4 3.3 0.1 6.8 7.0 5.5 0.3 7.1 3.9 25.8 6.6 6.8 7.4 7.7 10.4 5.0 8.1 0.8 7.8 2.7 3.1 3.8 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 PIGF ENSG00000151665 "Phosphatidylinositol glycan anchor biosynthesis class F" Q07326 2 46580937-46617055 "Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051389 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051389: AB_2681464" "unprognostic (3.85e-3)" "unprognostic (5.42e-2)" "unprognostic (1.11e-3)" "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (4.52e-3)" "prognostic unfavorable (1.39e-5)" "unprognostic (4.97e-2)" "unprognostic (9.29e-3)" "unprognostic (6.08e-2)" "unprognostic (5.89e-2)" "unprognostic (9.40e-2)" "unprognostic (1.02e-1)" "unprognostic (7.30e-3)" "unprognostic (1.84e-1)" "unprognostic (6.04e-2)" "unprognostic (6.71e-2)" 16.7 29.0 16.8 18.3 19.3 10.3 17.0 20.3 21.0 12.7 19.8 18.4 17.3 11.1 27.8 15.7 14.9 18.2 17.0 17.1 20.9 20.1 16.6 12.6 15.7 19.8 19.2 13.7 23.0 20.1 15.5 17.4 20.2 15.4 19.1 25.3 21.9 9.9 25.8 12.2 17.9 7.6 21.5 13.3 16.4 26.2 18.4 8.4 22.8 14.4 12.4 18.5 11.6 22.5 31.0 18.9 39.7 22.9 47.2 48.8 22.1 37.5 22.8 15.1 15.1 9.4 22.2 18.2 68.8 25.3 39.9 25.1 35.9 27.1 30.4 52.1 36.7 36.2 13.9 49.9 27.5 23.1 25.6 33.4 40.7 23.1 34.7 50.5 41.8 16.6 33.8 51.5 56.7 8.7 18.1 22.5 31.3 64.9 29.7 18.7 36.4 38.2 44.0 32.9 27.6 35.1 17.1 24.4 57.0 35.1 14.4 27.7 27.1 25.2 29.0 35.8 36.7 25.8 31.2 32.2 27.6 43.8 45.0 3.6 12.5 11.5 9.3 18.4 10.2 11.8 11.2 9.4 14.4 14.0 8.2 10.7 6.2 10.9 17.7 19.1 14.7 6.6 16.8 19.3 20.3 21.0 17.1 20.9 19.8 19.2 20.2 21.5 18.4 22.5 35.0 9.6 18.5 32.0 23.8 25.5 38.0 93.5 30.1 32.9 35.9 34.0 3.7 30.0 54.3 20.2 29.2 39.2 24.6 18.3 35.2 29.6 65.0 31.9 26.3 26.4 17.4 17.9 21.9 29.7 53.4 24.7 18.8 25.8 19.0 34.5 26.7 22.4 37.6 37.0 24.4 26.3 81.4 22.5 21.5 29.5 14.9 24.8 30.2 30.0 27.9 71.1 23.7 41.2 70.7 21.1 23.8 16.1 38.6 45.6 26.0 31.7 38.1 27.4 6.6 20.9 31.3 96.4 41.8 37.9 34.1 32.3 19.7 39.1 36.8 44.9 CRIPT HSPC139 ENSG00000119878 "CXXC repeat containing interactor of PDZ3 domain" Q9P021 2 46616416-46630176 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046080, HPA056765" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA046080: AB_2679529, HPA056765: AB_2683230" "unprognostic (3.38e-2)" "unprognostic (4.08e-1)" "unprognostic (1.67e-1)" "unprognostic (7.51e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.10e-1)" "unprognostic (6.07e-2)" "unprognostic (1.54e-2)" "unprognostic (3.38e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.12e-2)" "unprognostic (4.42e-2)" 7.0 7.7 4.7 2.2 4.6 6.0 6.6 7.6 6.0 5.9 5.3 7.2 3.0 5.9 5.5 6.3 5.5 1.8 11.9 4.8 4.1 7.2 6.1 4.3 3.3 5.5 4.3 7.2 5.4 2.7 6.0 2.1 5.0 5.6 2.8 10.7 7.0 1.9 12.3 6.1 5.6 2.2 3.6 4.7 6.3 5.8 4.6 2.4 4.7 2.8 3.1 6.3 6.3 7.8 3.8 2.5 2.3 2.4 2.7 2.9 3.4 2.7 1.8 1.7 1.7 2.9 2.7 2.9 5.7 2.9 2.4 2.6 2.3 2.4 3.3 4.4 2.6 3.6 3.4 3.8 3.1 2.8 2.2 3.3 2.9 2.4 1.7 3.2 2.7 1.6 3.7 3.4 2.1 2.4 1.9 3.5 3.0 3.6 2.5 1.7 4.6 4.4 3.2 2.7 4.2 6.7 3.1 2.4 3.2 2.3 2.0 2.1 3.5 2.7 2.6 2.7 3.0 3.7 3.1 2.8 4.1 3.1 2.3 6.3 2.6 3.8 2.9 2.3 2.6 3.6 3.0 2.6 2.1 3.5 3.0 2.9 5.8 3.0 2.4 3.2 3.6 1.9 4.7 4.6 7.6 6.0 4.8 4.1 5.5 4.3 5.0 3.6 4.6 7.8 28.6 19.2 13.7 19.2 34.5 43.1 65.5 71.3 28.5 28.9 56.5 54.4 60.4 45.8 51.8 31.3 25.0 56.7 48.4 38.5 68.4 64.5 41.8 46.4 33.7 29.5 65.1 91.8 22.5 39.8 81.4 35.1 20.4 37.7 28.5 28.3 38.6 57.5 48.1 16.8 25.7 39.9 42.7 38.9 30.2 15.9 36.4 29.3 30.2 20.6 48.7 40.4 51.5 44.2 31.2 67.6 58.4 25.6 46.2 58.6 81.0 102.6 48.7 51.2 19.7 26.0 48.0 56.0 49.6 39.1 53.0 95.6 35.8 26.2 32.6 74.9 SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 121.0;fHDF/TERT166: 121.9;U-138 MG: 80.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: AB_1857356" "unprognostic (1.69e-1)" "unprognostic (1.98e-2)" "unprognostic (5.71e-2)" "unprognostic (1.64e-2)" "unprognostic (2.20e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (4.52e-2)" "unprognostic (9.13e-2)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.10e-3)" "unprognostic (3.01e-1)" "unprognostic (1.47e-3)" "unprognostic (8.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" 12.0 10.2 7.6 6.3 7.7 7.7 13.0 15.9 9.6 13.0 7.5 9.7 5.2 14.1 9.1 8.5 9.3 11.3 11.3 8.1 7.6 9.2 6.7 8.7 6.7 8.3 8.3 23.2 6.2 14.2 5.6 7.3 8.5 9.9 6.6 12.7 8.7 12.4 9.0 7.5 6.7 13.9 8.5 9.0 6.6 10.3 8.2 7.6 9.9 16.0 6.7 9.3 8.5 8.6 14.5 10.8 9.3 13.8 29.9 42.3 11.4 66.5 121.0 31.5 18.6 10.3 6.9 7.5 12.7 121.9 9.7 7.1 9.9 10.8 41.2 7.3 9.4 11.8 10.0 13.2 18.4 6.9 12.7 33.9 15.8 26.7 10.7 35.8 11.0 3.0 10.2 8.1 21.5 5.3 5.9 12.0 10.4 15.1 8.7 7.8 15.9 9.5 13.2 11.1 7.3 19.8 16.4 10.7 13.0 8.9 4.4 10.3 12.8 80.0 17.7 26.9 13.2 9.7 6.4 6.5 36.9 13.7 25.5 0.5 0.4 2.5 0.9 0.4 1.1 1.8 0.5 0.6 0.5 3.0 1.1 1.5 0.4 1.0 1.7 0.5 1.0 0.7 7.6 7.7 15.9 9.6 8.1 7.6 8.3 8.3 8.5 8.5 8.2 8.6 17.2 3.2 6.1 18.9 11.3 16.6 7.2 8.3 16.5 12.8 15.1 12.2 14.2 18.6 8.0 3.7 22.9 3.7 6.2 11.0 5.9 7.3 12.3 9.9 29.2 24.3 10.8 6.1 43.4 6.8 2.5 18.8 10.2 12.0 17.1 17.4 17.2 7.9 4.5 18.5 51.5 7.1 2.0 8.4 15.2 8.1 17.4 7.7 7.2 18.7 8.4 9.7 6.2 38.2 25.4 6.8 8.8 17.0 7.0 11.0 5.1 7.3 5.3 5.5 13.1 13.8 20.1 13.3 18.8 9.9 14.5 2.7 7.0 7.3 5.6 7.8 MCFD2 "F5F8D, LMAN1IP, SDNSF" ENSG00000180398 "Multiple coagulation factor deficiency 2, ER cargo receptor complex subunit" Q8NI22 2 46901870-46941855 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 253.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022410, HPA034593" Supported "Intracellular and membrane" NA NA 1200000 "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "CAB022410: , HPA034593: AB_2674239" "unprognostic (1.16e-2)" "unprognostic (5.71e-3)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (2.50e-1)" "unprognostic (2.87e-2)" "unprognostic (3.98e-2)" "unprognostic (3.10e-2)" "unprognostic (3.93e-2)" "unprognostic (8.32e-2)" "unprognostic (1.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.64e-4)" 52.0 155.5 41.3 35.6 43.1 34.7 55.1 38.1 40.3 50.4 69.5 32.2 32.5 54.5 42.1 45.9 41.9 44.9 42.3 41.3 46.8 59.4 111.8 45.0 32.1 33.5 41.3 79.2 104.1 52.5 38.7 70.1 41.6 54.0 26.9 83.3 149.7 82.9 83.3 26.0 33.4 52.5 28.0 44.6 33.9 30.9 48.6 30.8 121.0 84.6 34.2 41.2 29.2 34.7 147.7 86.9 74.7 59.7 151.5 215.1 115.4 248.4 254.1 129.4 116.8 116.9 109.4 96.4 297.7 294.7 154.3 81.8 67.0 127.0 207.7 64.5 67.2 101.9 87.1 182.5 236.5 94.8 158.6 163.2 77.8 206.7 178.7 247.9 210.8 28.0 199.3 56.0 266.8 48.7 56.9 67.6 63.9 102.3 84.1 68.3 133.2 106.7 80.3 59.3 23.9 62.2 93.1 46.9 116.0 86.3 33.1 80.6 341.1 298.3 130.5 97.0 164.2 42.0 43.8 76.4 320.2 88.0 100.8 27.2 21.4 29.7 9.6 23.3 12.2 12.5 10.9 10.2 18.4 12.8 14.3 9.8 12.0 9.9 18.3 16.9 9.7 14.0 41.3 43.1 38.1 40.3 41.3 46.8 33.5 41.3 41.6 28.0 48.6 34.7 50.8 105.8 89.1 16.6 29.6 48.2 56.5 65.3 36.5 69.3 64.4 48.5 70.3 38.6 68.8 47.8 39.6 75.5 25.4 26.6 21.5 88.6 144.3 76.4 60.2 64.7 26.8 28.2 19.6 178.5 64.5 70.1 20.4 69.9 50.5 44.1 53.9 155.1 54.5 38.7 23.8 28.5 18.3 40.5 31.3 113.7 62.7 39.2 12.4 7.5 33.8 253.2 12.3 16.1 16.2 152.7 23.1 59.5 43.8 82.4 42.2 41.3 69.6 51.3 65.7 63.9 55.4 48.9 32.6 39.6 44.9 102.1 23.4 74.3 22.8 75.8 TTC7A "KIAA1140, TTC7" ENSG00000068724 "Tetratricopeptide repeat domain 7A" Q9ULT0 2 46916157-47076137 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 168.0;Microglial cells: 77.8;Oligodendrocytes: 86.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "REH: 90.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036781, HPA036782" Enhanced NA NA "Cluster 30: Non-specific - Translation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA036781: AB_10673665, HPA036782: AB_10671711" "unprognostic (2.51e-1)" "unprognostic (1.43e-1)" "unprognostic (8.56e-2)" "unprognostic (1.67e-2)" "unprognostic (4.01e-2)" "unprognostic (1.03e-3)" "unprognostic (1.51e-3)" "unprognostic (3.60e-1)" "unprognostic (4.36e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (3.19e-3)" "unprognostic (1.15e-1)" "unprognostic (5.06e-3)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" 8.7 16.8 2.5 6.9 4.1 18.4 6.6 3.7 3.3 6.3 10.1 6.7 12.9 4.1 1.9 14.0 5.0 3.8 3.7 2.6 3.7 6.2 5.7 12.5 10.4 6.6 4.5 4.3 16.1 4.6 4.5 5.7 5.6 4.9 5.7 4.0 12.9 4.3 1.9 12.7 12.5 2.7 3.8 10.6 10.3 40.8 4.2 29.1 10.4 0.8 14.6 4.8 8.8 5.6 39.9 14.6 4.6 1.3 6.9 8.5 19.2 10.7 14.2 6.9 6.4 22.6 23.2 26.5 10.2 19.9 8.0 16.4 6.4 13.5 5.6 51.9 5.3 2.7 11.6 24.1 2.9 10.8 10.4 3.4 15.9 8.6 10.6 8.1 5.6 10.2 10.4 17.5 3.9 14.8 54.5 11.4 5.1 42.5 3.7 90.0 7.8 47.6 6.5 10.0 5.8 5.4 19.8 39.8 3.5 8.5 7.5 22.7 14.1 7.8 6.0 5.9 9.0 10.7 4.3 13.5 5.7 13.0 4.4 0.0 1.5 0.0 0.3 0.8 0.3 1.2 0.9 0.3 0.7 1.1 0.6 0.2 0.3 0.2 0.3 1.6 0.3 0.4 2.5 4.1 3.7 3.3 2.6 3.7 6.6 4.5 5.6 3.8 4.2 5.6 2.4 22.4 12.4 32.0 22.0 6.5 4.8 5.1 9.1 1.9 4.7 2.7 4.3 11.5 5.4 7.3 0.0 8.0 16.7 29.1 3.9 5.1 52.9 27.9 10.9 5.0 6.7 7.4 24.2 7.5 11.2 8.4 13.3 15.4 8.2 4.7 1.8 9.2 16.4 0.0 18.8 9.4 0.0 29.5 15.7 168.0 4.7 24.6 5.4 77.8 18.6 22.6 1.0 17.6 86.8 22.2 11.8 6.8 22.9 3.1 38.7 4.6 12.4 3.7 0.0 8.0 5.2 6.1 6.8 12.2 5.5 4.0 11.5 2.9 7.6 4.5 STPG4 "C2orf61, FLJ40172" ENSG00000239605 "Sperm-tail PG-rich repeat containing 4" Q8N801 2 47045538-47155308 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 23 "testis: 14.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA047366, HPA052691" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" Nucleoplasm Cytosol "HPA047366: , HPA052691: AB_2681918" "unprognostic (6.74e-3)" "unprognostic (5.81e-4)" "unprognostic (3.43e-2)" "unprognostic (1.23e-3)" "unprognostic (1.72e-1)" "unprognostic (1.55e-3)" "unprognostic (4.36e-2)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (2.78e-2)" "unprognostic (2.36e-3)" "unprognostic (6.23e-2)" "unprognostic (3.64e-6)" "unprognostic (5.14e-2)" "unprognostic (6.00e-2)" "unprognostic (1.39e-1)" "unprognostic (2.53e-1)" 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.6 0.2 0.0 0.0 0.1 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 14.7 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.2 0.1 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.4 0.3 0.3 0.4 0.6 0.2 0.4 0.2 0.4 0.1 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CALM2 "CAMII, PHKD" ENSG00000143933 "Calmodulin 2" P0DP24 2 47160083-47176921 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007790, HPA044999" Approved NA Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB007790: AB_562257, HPA044999: AB_2679177" "prognostic unfavorable (5.05e-4)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (9.21e-2)" "unprognostic (2.04e-3)" "prognostic unfavorable (8.35e-5)" "unprognostic (1.63e-2)" "unprognostic (4.67e-3)" "unprognostic (1.79e-2)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (2.29e-2)" "prognostic favorable (1.94e-5)" "unprognostic (1.24e-1)" 509.3 652.1 1177.9 334.4 1219.1 240.3 686.1 1229.7 1745.6 420.1 988.8 683.9 549.8 507.6 551.1 366.8 526.5 390.8 443.0 1229.0 1219.0 445.7 493.1 505.6 427.9 1209.1 1192.8 416.1 213.3 332.3 441.3 468.9 1227.6 449.1 706.0 574.8 490.8 561.5 262.9 304.2 621.2 634.7 1209.4 643.0 390.4 508.8 1257.9 571.0 443.3 258.1 467.2 459.0 340.2 1411.8 2459.6 905.8 1062.2 459.7 579.4 679.5 655.8 2177.2 1504.3 1437.1 1240.1 958.1 923.2 956.1 979.5 1753.2 1030.4 624.7 878.3 855.6 1907.0 729.3 438.6 821.6 526.6 1409.6 779.5 996.3 686.2 381.2 825.0 1265.3 1347.0 1230.4 977.3 312.8 812.1 854.7 3485.7 635.9 1270.2 984.3 801.3 2961.6 488.6 314.3 1142.9 1021.9 1631.0 441.0 756.8 2016.6 726.5 756.0 1120.1 1144.3 573.7 556.7 1084.8 1060.8 1135.8 627.0 1703.6 648.8 529.1 1038.2 718.8 711.3 1357.7 944.7 447.6 776.8 139.7 844.1 177.2 285.6 203.4 213.2 354.0 182.1 173.7 201.6 417.9 277.1 761.4 445.6 227.4 496.5 1177.9 1219.1 1229.7 1745.6 1229.0 1219.0 1209.1 1192.8 1227.6 1209.4 1257.9 1411.8 597.4 1387.8 613.5 195.2 570.7 1780.5 1101.0 2616.3 524.8 654.3 844.4 572.9 639.6 581.9 1751.8 759.6 98.0 931.4 649.8 906.5 2304.8 1977.0 312.7 889.1 363.8 652.0 597.1 697.1 317.5 683.4 627.9 943.6 354.8 452.5 665.4 484.5 280.6 536.6 1267.1 341.6 179.0 1020.1 3352.8 867.1 1858.2 287.0 1055.3 911.0 1771.6 143.4 1167.2 2063.1 350.1 129.7 339.8 2584.9 1114.4 863.6 309.7 1016.8 1231.6 1020.2 3245.3 334.2 907.2 671.6 1882.0 2193.5 714.3 503.0 1663.1 255.3 669.1 615.4 771.1 1062.2 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 KCNK12 "K2p12.1, THIK-2, THIK2" ENSG00000184261 "Potassium two pore domain channel subfamily K member 12" Q9HB15 2 47509290-47570985 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 7.0;pituitary gland: 3.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.2;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.0;Extravillous trophoblasts: 33.7;Inhibitory neurons: 30.4;NK-cells: 11.3" "Cancer enriched" "Detected in single" 12 "testis cancer: 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 10.5;SCLC-21H: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 6: Brain - Smell perception" "Cluster 14: REH - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (6.10e-2)" "unprognostic (1.24e-1)" "unprognostic (6.02e-3)" "unprognostic (3.29e-2)" "unprognostic (2.50e-1)" "unprognostic (3.77e-2)" "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (2.54e-2)" "unprognostic (2.14e-1)" "unprognostic (6.55e-3)" "unprognostic (2.12e-1)" "unprognostic (1.12e-6)" "unprognostic (1.36e-1)" "unprognostic (1.34e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-1)" 0.1 0.1 1.5 0.1 1.2 0.1 0.0 7.0 5.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.3 0.0 0.0 0.0 0.1 3.0 0.4 0.0 0.0 0.0 3.5 0.1 2.9 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.6 0.0 0.3 10.5 0.0 0.8 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 1.2 7.0 5.6 1.5 0.3 3.0 0.4 2.9 0.9 1.0 2.4 0.2 0.0 0.0 0.3 3.2 0.1 0.1 0.0 0.0 10.2 0.2 0.3 1.3 0.0 0.0 0.0 14.6 0.2 2.6 0.0 0.0 0.0 8.3 0.2 0.4 0.1 0.0 0.4 19.0 0.0 33.7 0.3 0.5 0.1 0.0 1.0 0.0 0.0 0.4 1.7 30.4 0.0 0.0 0.3 0.4 5.2 0.3 0.0 0.0 0.0 0.1 0.6 11.3 1.0 8.2 0.0 0.0 0.4 4.7 0.6 0.0 0.1 0.0 5.3 0.0 0.2 0.4 3.9 2.5 0.0 0.0 0.8 3.0 1.3 0.0 0.1 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 FBXO11 "FBX11, UBR6" ENSG00000138081 "F-box protein 11" Q86XK2 2 47789316-47906498 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002690 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "HPA002690: AB_1848448" "unprognostic (1.18e-1)" "unprognostic (8.65e-3)" "unprognostic (3.93e-2)" "unprognostic (2.05e-2)" "unprognostic (7.92e-2)" "unprognostic (1.42e-1)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (2.55e-2)" "unprognostic (9.82e-2)" "unprognostic (5.77e-2)" "unprognostic (2.33e-2)" "unprognostic (3.21e-2)" "unprognostic (1.55e-1)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.20e-2)" 27.9 19.6 24.5 19.1 25.9 32.2 20.9 32.7 28.7 21.1 21.0 19.7 16.8 33.1 24.8 18.7 22.2 20.9 22.8 26.5 25.6 21.7 26.8 22.5 25.7 22.8 23.1 34.4 19.6 30.2 17.5 23.0 24.0 22.7 20.1 33.3 16.5 20.4 28.3 19.1 17.3 29.7 22.9 24.2 19.1 41.0 25.9 22.5 26.1 28.7 27.7 22.1 16.9 25.2 52.8 26.9 62.9 53.9 42.6 40.2 37.2 36.0 48.6 32.6 31.9 22.9 25.9 32.8 45.4 50.2 40.5 25.6 42.5 37.1 47.9 22.3 21.5 31.6 21.3 36.6 41.0 33.5 32.1 39.3 41.7 28.8 48.2 51.9 42.1 16.6 31.3 33.9 40.4 25.5 31.7 32.8 38.2 34.7 26.2 40.9 58.3 25.5 47.1 42.5 44.1 52.3 34.2 31.5 54.6 46.4 14.7 27.9 46.4 40.2 37.2 27.5 40.0 28.9 16.5 60.9 27.4 30.8 42.1 4.3 1.1 2.1 1.5 1.2 1.6 2.1 1.4 1.7 1.4 1.5 2.6 1.7 2.6 2.2 1.1 2.0 1.6 1.1 24.5 25.9 32.7 28.7 26.5 25.6 22.8 23.1 24.0 22.9 25.9 25.2 40.6 16.0 39.0 100.9 34.1 67.0 44.4 22.0 24.5 45.1 22.3 15.1 11.0 15.7 24.9 18.4 33.3 19.6 37.8 24.7 11.7 17.2 34.4 38.6 40.3 39.4 23.9 17.1 151.4 15.2 16.0 37.0 23.4 48.6 29.1 37.3 33.2 20.0 25.5 55.5 134.8 17.1 24.4 40.1 81.4 40.4 30.1 51.8 35.6 137.7 30.9 30.2 25.7 138.7 143.8 25.8 17.1 39.9 36.3 44.3 17.3 14.6 37.4 42.5 19.7 42.3 34.6 86.6 50.7 24.2 59.0 36.0 35.6 33.4 19.5 65.1 FOXN2 HTLF ENSG00000170802 "Forkhead box N2" P32314 2 48314637-48379295 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 54.0;brain: 53.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 152.3;Oligodendrocytes: 282.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003485 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA003485: AB_1078905" "unprognostic (5.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.65e-3)" "prognostic favorable (3.85e-4)" "unprognostic (4.00e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-1)" "unprognostic (8.95e-2)" "unprognostic (2.59e-1)" "unprognostic (5.15e-3)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (2.24e-2)" "unprognostic (1.55e-1)" "unprognostic (2.34e-2)" "unprognostic (1.12e-2)" 17.9 5.5 13.3 15.4 30.3 54.0 8.0 25.3 19.0 7.7 4.2 7.7 8.3 6.7 4.2 9.3 5.5 9.7 8.6 13.9 16.3 6.6 19.8 9.5 19.4 24.1 21.0 5.9 8.9 9.5 3.0 13.4 21.9 5.0 8.0 3.4 5.5 4.2 4.8 3.6 10.3 9.8 20.0 18.1 7.9 6.3 19.2 14.9 6.9 6.4 17.1 10.6 3.9 53.3 13.1 19.5 22.2 19.6 17.2 12.7 24.3 14.4 15.8 11.9 13.2 17.3 15.9 28.4 18.7 17.0 14.5 16.2 13.7 16.5 17.2 22.3 11.7 56.1 13.3 17.4 30.0 30.9 42.1 11.4 6.9 12.9 22.3 9.6 12.8 11.6 26.6 32.7 19.5 10.1 34.4 20.3 16.8 9.8 10.2 17.0 46.5 23.2 10.2 16.5 12.4 12.6 6.9 13.2 24.9 7.5 5.7 18.0 15.0 16.0 16.1 15.2 15.2 17.8 14.2 40.5 13.9 27.5 22.2 120.9 32.4 129.6 24.0 26.2 27.4 21.2 23.1 22.4 33.6 20.6 17.2 17.7 40.8 25.7 36.4 20.8 28.8 17.2 13.3 30.3 25.3 19.0 13.9 16.3 24.1 21.0 21.9 20.0 19.2 53.3 22.1 0.0 7.4 66.6 31.3 15.6 27.5 10.0 15.4 6.7 5.4 5.6 11.1 14.3 6.1 1.8 0.0 6.7 28.3 7.0 5.9 6.0 4.8 8.9 17.2 21.8 2.4 22.5 28.1 5.4 32.1 13.3 14.3 13.3 22.8 1.2 20.7 19.7 17.9 13.5 25.2 8.0 8.2 39.5 47.3 4.7 12.2 44.4 12.4 35.6 44.1 7.8 26.8 152.3 282.0 11.0 7.1 11.3 31.0 35.2 11.3 4.8 3.3 3.6 6.6 17.8 27.4 22.7 13.1 11.9 21.2 16.6 38.3 2.8 8.9 35.9 PPP1R21 "CCDC128, FLJ16566, KLRAQ1" ENSG00000162869 "Protein phosphatase 1 regulatory subunit 21" Q6ZMI0 2 48440598-48515391 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 99.6;Oligodendrocytes: 190.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036791, HPA036792" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036791: AB_10671713, HPA036792: AB_2675317" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (1.57e-2)" "unprognostic (1.01e-1)" "unprognostic (2.78e-3)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (3.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.13e-1)" "prognostic favorable (4.59e-6)" "unprognostic (9.23e-2)" "unprognostic (1.93e-1)" "prognostic favorable (9.87e-4)" "unprognostic (6.60e-2)" 9.3 10.6 10.6 10.5 13.4 9.9 8.5 8.2 13.4 8.5 10.7 8.8 7.9 12.7 19.6 12.1 14.5 10.8 10.1 9.7 9.4 28.1 11.6 11.2 13.3 11.1 11.0 13.4 8.1 33.5 9.6 12.8 10.2 11.4 10.6 12.0 5.7 10.6 5.7 10.5 9.9 13.0 8.7 13.0 9.0 9.4 11.7 13.9 21.4 4.8 12.2 9.5 7.6 18.9 17.3 8.2 6.8 8.5 17.1 12.5 18.3 10.0 11.0 6.1 7.2 4.5 10.6 11.8 16.4 14.2 11.7 9.3 5.8 9.1 12.4 15.1 4.8 12.6 7.2 10.8 11.6 5.5 9.8 15.9 8.1 11.0 13.2 15.1 15.3 5.9 5.2 19.2 16.7 9.5 10.9 9.5 17.7 12.3 8.4 9.1 18.8 13.1 11.9 10.8 9.2 5.7 19.0 4.8 18.1 18.2 8.6 9.0 13.9 6.4 7.8 5.6 8.0 14.3 4.1 10.5 10.2 12.5 8.6 18.6 4.7 8.1 3.7 5.4 2.9 5.4 4.3 4.4 5.0 6.8 6.4 5.5 11.6 3.8 4.8 3.1 4.6 2.3 10.6 13.4 8.2 13.4 9.7 9.4 11.1 11.0 10.2 8.7 11.7 18.9 14.5 22.4 16.5 37.5 23.6 10.5 32.9 8.6 13.6 9.1 6.9 6.7 11.0 14.3 9.2 25.8 2.1 21.7 8.5 11.7 5.9 11.0 3.9 10.2 11.5 10.9 18.7 10.3 99.6 8.4 16.3 15.0 25.5 12.3 12.0 12.4 10.8 13.6 35.2 28.6 49.6 10.7 10.2 26.1 12.2 5.7 12.2 19.3 12.4 44.0 24.3 21.2 19.6 69.9 190.3 12.2 9.3 20.7 19.4 17.0 10.7 59.3 20.0 6.8 13.1 9.6 14.2 9.8 10.8 17.4 14.1 27.1 20.5 12.1 8.4 27.2 STON1 "SBLF, stoned-b1" ENSG00000243244 "Stonin 1" Q9Y6Q2 2 48529383-48598513 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 42.0;Muller glia cells: 33.4;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;neutrophil: 1.0" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "ASC diff: 23.7;ASC TERT1: 28.6;HSkMC: 36.1;hTERT-RPE1: 17.0;SuSa: 19.6" "Low region specificity" "Detected in all" HPA005715 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "HPA005715: AB_1080113" "unprognostic (1.61e-1)" "unprognostic (4.44e-1)" "unprognostic (7.97e-2)" "unprognostic (1.02e-4)" "unprognostic (1.54e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "unprognostic (8.99e-3)" "unprognostic (1.09e-1)" "unprognostic (1.76e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.69e-4)" "unprognostic (1.06e-2)" "unprognostic (2.50e-1)" "unprognostic (8.68e-2)" "unprognostic (2.49e-3)" 20.8 5.2 2.3 5.7 2.8 0.5 10.9 10.5 2.0 10.5 10.7 34.5 3.6 27.4 4.6 16.0 17.2 15.6 6.4 1.9 7.1 9.3 2.1 10.9 2.8 33.2 12.5 24.5 1.9 2.1 2.8 18.4 25.9 21.7 8.4 18.1 2.5 19.3 2.2 4.1 7.9 25.1 25.6 7.4 13.0 1.1 4.1 2.5 4.6 6.3 1.4 22.2 10.5 29.2 0.1 0.0 8.6 0.1 23.7 28.6 4.9 1.0 9.2 0.9 2.1 0.1 0.0 0.0 0.3 12.0 4.6 9.0 8.3 0.3 1.7 0.1 2.3 1.4 0.6 0.0 13.5 0.0 0.4 36.1 1.7 2.5 1.0 17.0 16.4 0.8 0.2 0.2 5.7 0.5 0.7 0.3 8.0 0.0 0.1 1.3 1.7 0.0 0.9 6.6 0.3 1.9 0.7 1.5 4.0 19.6 0.7 0.3 8.8 3.0 2.3 0.0 0.7 0.5 0.1 0.0 1.6 0.1 1.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.3 2.8 10.5 2.0 1.9 7.1 33.2 12.5 25.9 25.6 4.1 29.2 16.4 0.0 0.5 0.0 1.1 2.4 15.4 1.1 16.5 3.8 0.8 1.8 2.3 0.0 0.8 5.5 2.1 15.1 0.5 0.6 3.9 0.8 0.4 1.9 42.0 7.7 2.4 0.0 0.0 0.4 1.0 9.9 0.5 2.6 0.0 3.9 11.4 0.2 2.7 13.5 0.0 0.3 0.0 1.3 2.8 0.9 12.2 1.6 0.0 0.0 1.2 33.4 1.0 0.0 0.0 0.4 0.3 10.1 0.2 13.8 0.4 2.0 0.6 2.3 26.3 1.9 15.1 0.3 1.7 1.9 2.4 12.6 1.5 2.6 0.9 14.3 STON1-GTF2A1L SALF ENSG00000068781 "STON1-GTF2A1L readthrough" 2 48529925-48776517 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1" "Cell type enhanced" "Detected in some" "Early spermatids: 8.4;Excitatory neurons: 2.9;Late spermatids: 2.2;Oligodendrocyte precursor cells: 12.1;Spermatocytes: 8.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 2.1;ASC TERT1: 2.0;HSkMC: 1.4;hTERT-RPE1: 3.6;SuSa: 7.3" HPA005715 Uncertain NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA005715: AB_1080113" "unprognostic (5.66e-3)" "unprognostic (8.85e-2)" "unprognostic (1.18e-3)" "unprognostic (8.26e-2)" "unprognostic (5.08e-2)" "unprognostic (3.53e-1)" "unprognostic (1.09e-1)" "unprognostic (2.59e-1)" "unprognostic (1.15e-1)" "unprognostic (7.59e-2)" "unprognostic (2.81e-1)" "unprognostic (1.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-1)" "unprognostic (1.46e-2)" 2.2 0.3 0.4 0.8 0.6 0.0 0.3 2.9 0.6 1.6 2.0 3.6 0.2 2.1 0.5 1.3 1.3 2.1 0.2 0.4 1.1 0.6 0.0 0.4 0.0 6.7 3.0 1.8 0.0 0.0 0.1 0.7 7.1 0.8 0.9 2.1 0.0 0.9 0.0 0.0 0.4 2.5 4.8 0.5 1.0 0.5 0.8 0.1 0.1 0.0 0.0 2.6 0.4 6.5 0.0 0.0 0.8 0.0 2.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.1 1.4 0.1 0.0 0.0 3.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 2.9 0.6 0.4 1.1 6.7 3.0 7.1 4.8 0.8 6.5 0.2 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.0 0.4 0.0 12.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 GTF2A1L ALF ENSG00000242441 "General transcription factor IIA subunit 1 like" Q9UNN4 2 48617798-48733148 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 60.0" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Late spermatids: 2.3;Spermatocytes: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.6;hTERT-RPE1: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.59e-1)" "unprognostic (7.00e-2)" "unprognostic (2.63e-1)" "unprognostic (4.77e-1)" "unprognostic (5.02e-2)" 2.1 0.5 0.5 0.0 0.5 0.0 1.2 1.4 0.8 2.9 0.7 8.7 0.4 4.2 0.4 0.7 2.9 1.1 0.8 0.4 0.6 1.1 0.2 1.1 0.2 3.4 1.0 2.1 0.2 0.0 0.5 0.2 2.6 2.1 0.1 0.1 0.2 0.2 0.6 0.4 1.7 0.6 2.0 1.3 2.6 60.0 0.8 0.1 0.5 0.1 0.0 4.2 1.6 2.2 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.8 0.4 0.6 3.4 1.0 2.6 2.0 0.8 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2;ovary: 2.1;testis: 2.2" "Cell type enriched" "Detected in some" 22 "Theca cells: 143.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009814 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 52: Non-specific - Transcription" "CAB009814: AB_2135467" "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" 1.3 0.8 0.3 0.0 0.4 0.0 0.7 0.9 0.5 0.0 0.7 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.2 0.6 0.2 0.0 0.1 0.0 3.2 0.7 2.1 0.0 0.0 0.5 0.0 2.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 2.2 0.8 0.2 0.6 0.1 0.0 0.3 0.0 1.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.9 0.5 0.2 0.6 3.2 0.7 2.0 1.6 0.8 1.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 5.3 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.3 1.0 1.2 0.1 0.0 6.5 0.0 0.0 0.0 2.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 143.2 0.0 0.0 FSHR "FSHRO, LGR1, ODG1" ENSG00000170820 "Follicle stimulating hormone receptor" P23945 2 48962157-49154527 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.0;ovary: 2.0;testis: 2.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 10.1;Granulosa cells: 33.8;Late spermatids: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (5.94e-2)" "unprognostic (4.06e-3)" "unprognostic (5.78e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.8 2.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.3 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.0 0.6 0.8 0.4 0.3 0.5 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 ASB3 ASB-3 ENSG00000115239 "Ankyrin repeat and SOCS box containing 3" Q9Y575 2 53532672-53860160 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003940 Uncertain NA NA "Cluster 46: Basophils - DNA binding" "Cluster 6: Brain - Smell perception" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "HPA003940: AB_1845067" "unprognostic (8.32e-2)" "unprognostic (3.42e-2)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (3.31e-3)" "unprognostic (4.77e-1)" "unprognostic (1.64e-4)" "unprognostic (5.45e-5)" "unprognostic (6.73e-2)" "unprognostic (2.57e-1)" "unprognostic (2.07e-1)" "unprognostic (4.82e-1)" "unprognostic (1.43e-5)" "unprognostic (3.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.05e-2)" "unprognostic (1.82e-1)" 8.4 11.5 28.1 8.3 29.9 15.0 10.3 32.0 32.8 10.4 14.3 7.6 6.7 11.4 14.0 8.4 9.5 7.8 9.6 29.1 23.8 9.0 10.8 10.0 11.0 18.9 25.9 12.2 7.4 10.3 14.5 11.5 18.4 13.0 8.0 23.4 8.8 10.2 7.2 9.6 8.6 8.2 17.5 12.7 7.1 11.5 24.7 17.2 11.6 7.7 12.2 7.9 9.8 27.9 15.4 12.5 26.8 10.6 17.6 14.7 23.0 16.3 11.5 12.2 15.2 10.8 10.9 14.5 26.1 11.6 22.6 9.4 19.6 12.1 18.0 29.0 17.6 16.0 16.2 21.2 13.7 20.7 12.2 12.3 8.0 11.4 22.4 21.1 15.1 18.9 17.6 17.9 18.1 9.9 23.4 27.3 20.7 14.3 10.8 21.5 20.2 11.9 13.9 12.8 19.1 15.0 18.8 17.4 15.3 23.2 6.8 11.4 13.9 19.0 11.3 15.1 18.8 26.4 13.3 8.1 16.3 15.5 16.3 16.6 6.9 12.9 9.0 6.6 12.7 12.2 10.4 10.2 7.5 10.4 11.1 11.1 5.0 11.2 7.5 6.2 11.6 6.8 28.1 29.9 32.0 32.8 29.1 23.8 18.9 25.9 18.4 17.5 24.7 27.9 5.9 25.6 23.2 16.3 14.4 0.0 6.3 0.0 12.5 16.1 5.1 6.1 0.0 5.7 14.9 1.8 4.2 11.6 6.4 1.5 0.0 4.8 5.0 6.6 7.2 6.0 1.2 9.0 3.6 2.7 10.0 9.1 7.1 3.1 16.4 5.5 4.6 4.4 4.6 3.3 3.1 3.6 0.0 5.7 0.0 2.5 9.6 5.9 0.0 3.7 4.0 10.1 9.2 26.7 3.5 4.4 1.5 9.8 18.9 3.2 3.3 3.9 12.4 10.3 6.6 6.5 5.7 16.8 14.5 8.9 0.0 7.7 11.3 6.5 3.0 3.4 CHAC2 GCG1 ENSG00000143942 "ChaC glutathione specific gamma-glutamylcyclotransferase 2" Q8WUX2 2 53767804-53775196 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 44.0;Plasma cells: 27.0;Spermatocytes: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049235 Approved Approved Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA049235: AB_2680686" "unprognostic (2.22e-1)" "unprognostic (1.31e-1)" "unprognostic (2.11e-2)" "unprognostic (3.91e-3)" "unprognostic (1.61e-2)" "unprognostic (4.74e-3)" "prognostic unfavorable (3.80e-7)" "unprognostic (5.52e-2)" "unprognostic (1.74e-2)" "unprognostic (1.30e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (4.28e-6)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" 5.0 4.4 1.6 4.8 1.7 6.9 2.1 2.4 2.4 1.2 0.9 4.4 7.3 1.1 2.6 4.5 0.7 1.3 2.5 1.6 2.0 2.9 4.4 1.4 6.6 1.6 1.6 0.6 1.9 1.3 1.6 1.1 1.5 1.7 3.7 3.7 1.7 1.5 4.9 1.2 4.5 2.2 1.3 4.2 4.5 5.4 1.8 4.9 1.0 4.7 6.5 3.2 2.2 1.4 39.9 13.0 13.5 12.1 6.7 3.3 2.9 17.9 3.6 12.5 14.8 9.1 10.0 33.5 25.3 7.8 18.8 14.0 31.1 21.3 21.7 71.3 27.1 26.6 16.3 15.0 10.2 31.8 11.6 4.2 6.2 23.2 17.5 3.3 24.8 23.0 27.8 19.2 16.6 13.0 38.0 26.5 17.5 17.1 23.1 28.6 28.9 34.2 17.3 10.6 16.8 4.7 20.7 15.3 8.7 8.1 9.3 12.5 11.0 7.3 26.1 28.2 29.3 18.9 26.1 28.8 9.9 39.5 10.2 1.3 0.3 0.8 3.5 0.7 3.7 4.3 3.8 3.9 0.8 4.4 4.3 4.1 1.0 1.1 0.5 1.8 3.9 1.9 1.6 1.7 2.4 2.4 1.6 2.0 1.6 1.6 1.5 1.3 1.8 1.4 2.3 0.0 1.1 2.0 11.7 3.4 3.7 7.4 0.6 1.6 2.2 2.0 3.0 7.2 4.1 1.8 0.0 1.9 5.1 3.4 11.7 5.4 13.1 2.2 1.0 3.0 0.0 44.0 4.8 8.0 0.9 1.6 10.2 2.2 1.3 1.5 3.3 7.6 7.8 1.7 4.3 4.6 2.0 1.9 3.0 3.5 2.8 1.7 3.6 1.0 5.8 5.7 8.2 5.0 2.1 7.9 1.4 4.1 27.0 4.1 3.7 9.8 1.9 6.8 0.0 2.4 3.1 47.0 6.6 5.5 3.4 0.4 5.3 5.1 10.6 4.0 ERLEC1 "C2orf30, CL25084, ERLECTIN, XTP3-B, XTP3TPB" ENSG00000068912 "Endoplasmic reticulum lectin 1" Q96DZ1 2 53787044-53818819 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 394.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031501, HPA031502, HPA031503" Enhanced "Intracellular and membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "HPA031501: AB_10600104, HPA031502: AB_10602174, HPA031503: AB_10670425" "unprognostic (1.27e-2)" "unprognostic (3.36e-3)" "unprognostic (3.17e-1)" "unprognostic (1.97e-3)" "unprognostic (1.08e-2)" "unprognostic (1.86e-1)" "unprognostic (3.27e-3)" "unprognostic (3.79e-1)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-2)" "unprognostic (1.47e-1)" "unprognostic (8.13e-2)" "unprognostic (2.33e-2)" "unprognostic (3.92e-2)" 38.4 51.0 30.2 31.3 32.1 33.8 48.7 29.3 41.9 66.4 39.3 45.8 37.7 40.9 93.9 26.1 36.2 41.0 45.2 32.9 39.2 38.1 43.4 44.1 32.4 28.7 31.1 38.0 67.1 57.3 59.4 56.6 31.5 72.8 50.2 54.5 54.0 55.9 32.1 20.1 34.0 38.5 30.1 33.1 55.3 42.4 31.5 28.1 72.5 39.5 41.2 44.7 27.2 34.4 42.1 47.3 44.4 27.4 123.3 111.3 65.5 100.5 109.1 49.0 51.4 31.3 55.7 29.4 94.5 106.3 86.3 29.7 29.2 42.3 62.1 67.0 38.7 36.1 29.1 93.8 84.4 60.2 63.9 70.5 69.4 51.6 83.3 99.4 58.1 28.6 39.0 115.8 73.6 35.3 27.7 48.0 34.1 67.1 30.4 24.9 53.1 82.7 57.7 39.3 26.5 46.3 36.6 79.0 64.6 50.3 38.0 45.9 63.3 53.9 47.2 44.0 60.3 170.1 120.3 16.5 88.2 35.8 64.5 77.0 25.1 30.7 41.4 27.8 45.8 36.8 36.3 39.9 28.0 28.6 33.9 39.0 9.6 45.4 33.3 40.1 36.6 41.5 30.2 32.1 29.3 41.9 32.9 39.2 28.7 31.1 31.5 30.1 31.5 34.4 57.2 89.8 116.7 22.2 86.3 25.1 42.5 88.0 34.1 77.0 76.3 54.6 83.5 52.9 93.5 66.2 31.3 100.2 60.9 43.4 33.2 76.1 168.4 67.7 77.5 63.8 55.1 23.1 24.0 115.7 105.8 99.7 54.6 101.7 74.1 36.6 68.6 81.8 60.1 95.9 28.5 169.7 107.8 39.7 31.5 117.9 88.3 41.7 80.0 17.8 61.7 79.7 72.1 20.6 25.3 90.2 42.8 84.2 394.0 113.4 32.3 51.4 118.2 68.6 52.6 55.6 109.5 146.1 65.3 40.3 33.4 183.6 57.0 48.3 57.1 67.5 GPR75 WI-31133 ENSG00000119737 "G protein-coupled receptor 75" O95800 2 53852912-53859967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Cone photoreceptor cells: 2.1;Gastric mucus-secreting cells: 2.0;Glandular and luminal cells: 1.9" "Cancer enriched" "Detected in many" 5 "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "unprognostic (1.88e-1)" "unprognostic (2.39e-2)" "unprognostic (2.77e-1)" "unprognostic (4.44e-2)" "unprognostic (5.96e-2)" "unprognostic (5.27e-3)" "unprognostic (8.31e-3)" "unprognostic (2.59e-3)" "unprognostic (4.71e-2)" "unprognostic (2.20e-1)" "unprognostic (3.07e-4)" "unprognostic (1.10e-1)" "unprognostic (3.97e-3)" "unprognostic (8.23e-2)" "unprognostic (1.94e-1)" "unprognostic (3.38e-1)" "unprognostic (5.75e-2)" 1.1 1.5 10.5 1.1 9.6 1.4 2.1 6.5 3.4 0.9 0.0 0.7 0.3 1.4 0.8 0.9 1.3 1.3 0.8 5.2 10.7 0.5 2.7 1.0 1.0 9.7 17.7 2.0 1.3 3.3 2.0 0.4 8.2 1.5 0.6 7.7 1.9 1.3 1.1 0.9 0.9 1.6 5.5 1.4 1.0 0.7 16.8 1.1 2.0 0.7 0.7 0.9 0.7 2.3 1.6 1.7 2.4 2.2 0.8 0.5 3.2 1.3 0.8 1.5 1.4 4.4 0.7 3.4 1.1 1.8 1.3 2.4 2.9 2.4 2.3 2.9 1.9 3.9 2.8 2.4 0.5 2.2 2.6 1.1 0.7 3.8 0.7 0.8 1.2 1.2 2.3 0.9 1.3 1.2 1.0 1.7 3.2 0.4 1.9 1.7 2.2 0.6 0.8 2.4 1.4 2.1 1.1 0.9 0.6 2.5 0.8 0.7 3.2 2.6 2.5 2.1 3.7 0.7 0.5 1.0 2.4 2.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 10.5 9.6 6.5 3.4 5.2 10.7 9.7 17.7 8.2 5.5 16.8 2.3 0.3 0.0 0.0 0.0 0.1 0.6 0.2 0.2 1.2 0.2 0.6 0.4 0.3 0.0 0.2 0.0 2.1 0.1 0.9 0.1 0.0 0.0 0.2 0.6 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.3 2.0 1.9 0.0 0.2 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.4 0.0 0.7 0.3 0.1 0.2 1.0 0.9 0.0 0.3 0.1 0.1 0.2 PSME4 "KIAA0077, PA200" ENSG00000068878 "Proteasome activator subunit 4" Q14997 2 53864069-53970993 "Predicted intracellular proteins" "Differentiation, DNA damage, DNA repair, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.8" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 238.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060922 Approved Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA060922: AB_2684386" "unprognostic (2.77e-2)" "unprognostic (1.57e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.26e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (4.84e-4)" "unprognostic (4.76e-2)" "unprognostic (6.67e-2)" "unprognostic (5.65e-2)" "unprognostic (3.72e-3)" "unprognostic (1.38e-1)" "unprognostic (1.80e-3)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-1)" 7.4 8.6 5.3 8.1 8.8 16.1 12.1 5.7 7.4 15.4 11.1 9.8 5.9 16.1 6.2 8.8 8.0 11.9 16.9 6.4 7.1 7.0 16.6 8.0 11.1 7.1 7.0 6.7 7.9 8.3 6.8 8.5 6.4 10.0 8.4 8.9 14.5 7.4 59.8 7.2 7.1 15.0 5.0 9.5 10.6 33.6 8.1 10.7 14.4 45.2 12.2 13.2 8.1 12.6 28.0 18.3 27.6 8.5 9.1 19.4 18.1 29.1 25.6 29.3 23.6 28.3 10.6 38.7 26.1 29.4 14.1 18.1 32.1 23.5 52.7 29.4 18.8 59.8 18.3 38.5 11.7 32.1 17.1 14.8 14.2 33.1 26.6 12.1 30.4 10.1 48.1 24.0 26.3 10.9 19.5 15.4 26.7 13.7 15.4 22.8 41.9 25.3 15.7 27.1 20.6 23.1 18.2 23.9 14.8 17.4 18.1 12.7 39.6 25.5 21.4 19.7 27.0 17.1 16.6 24.9 20.1 26.4 16.1 0.5 0.1 0.5 0.7 0.3 0.4 0.6 0.4 0.4 0.3 0.9 0.5 0.7 0.4 0.6 0.2 0.4 0.3 0.1 5.3 8.8 5.7 7.4 6.4 7.1 7.1 7.0 6.4 5.0 8.1 12.6 20.0 16.0 35.0 58.1 33.1 75.8 72.4 37.4 60.9 20.6 40.0 19.6 63.5 20.0 45.4 22.0 45.9 16.1 51.0 20.1 3.9 20.8 99.7 60.0 49.6 27.3 40.6 28.8 100.3 37.1 12.8 27.2 41.3 97.0 28.5 34.9 18.5 34.3 19.5 25.2 83.5 19.5 30.5 28.7 47.7 92.5 21.1 35.1 28.4 71.2 28.0 15.7 36.0 64.3 238.5 43.6 9.3 10.5 61.3 92.5 8.7 10.3 39.0 27.8 13.1 48.9 26.5 36.0 18.0 79.3 66.1 29.7 42.6 14.0 18.8 107.3 ACYP2 ENSG00000170634 "Acylphosphatase 2" P14621 2 53970838-54305300 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 207.4;tongue: 163.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 162.6;Excitatory neurons: 158.8;Oligodendrocytes: 180.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035301 Uncertain Approved Nucleoplasm "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA035301: AB_10670291" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (3.40e-1)" "unprognostic (2.16e-1)" "unprognostic (6.90e-3)" "unprognostic (6.21e-2)" "unprognostic (2.03e-3)" "unprognostic (3.17e-1)" "unprognostic (5.22e-2)" "unprognostic (7.83e-3)" "unprognostic (3.64e-3)" "unprognostic (1.16e-1)" "unprognostic (6.66e-2)" "unprognostic (2.13e-1)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" "unprognostic (2.24e-2)" 19.5 42.8 64.9 5.4 72.9 7.1 15.7 74.8 85.4 10.6 61.5 14.3 7.4 11.5 12.8 10.4 11.6 8.5 63.4 63.9 72.8 14.5 28.0 10.6 10.9 69.5 68.8 9.3 12.7 13.6 26.2 6.5 70.3 14.4 5.3 24.1 15.2 9.2 207.4 9.9 9.0 7.9 70.4 12.7 12.9 10.2 70.4 10.7 12.6 163.2 8.4 14.0 10.7 76.9 11.7 5.9 6.0 4.4 23.7 17.3 3.7 11.5 9.7 8.3 7.3 1.5 7.1 21.5 33.0 12.6 7.8 8.5 3.3 10.8 7.4 14.4 13.1 13.4 6.3 16.3 8.5 12.7 6.3 13.6 19.3 5.6 9.5 15.2 3.9 9.8 5.5 11.5 17.9 7.6 7.5 17.0 5.9 8.4 6.7 5.4 4.7 12.2 18.8 10.6 17.6 10.0 17.4 10.0 5.7 1.9 3.4 13.2 10.9 11.5 10.6 3.5 11.1 21.4 12.5 10.2 16.3 24.3 12.4 41.2 14.0 26.1 16.9 13.0 15.4 29.0 16.6 16.1 20.3 26.9 20.1 16.4 11.5 18.6 13.5 33.4 16.3 11.3 64.9 72.9 74.8 85.4 63.9 72.8 69.5 68.8 70.3 70.4 70.4 76.9 21.7 16.0 17.9 84.9 30.6 20.5 41.9 52.8 18.8 15.5 49.7 65.7 162.6 34.3 32.0 18.4 10.4 13.6 27.9 24.5 62.6 24.3 86.8 29.5 23.6 23.1 30.6 14.5 158.8 38.1 6.1 21.0 26.0 19.5 19.7 17.6 30.7 74.2 31.9 28.6 134.1 21.9 36.7 40.0 28.5 64.7 13.4 25.4 23.2 59.0 26.1 90.1 24.7 67.8 180.1 29.9 18.8 30.9 36.4 27.4 29.1 55.6 32.2 31.6 52.6 30.8 30.0 22.9 9.8 28.9 21.3 10.3 22.7 29.7 18.6 45.0 TSPYL6 ENSG00000178021 "TSPY like 6" Q8N831 2 54253178-54256229 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 21.5" "Group enriched" "Detected in some" 6 "Spermatocytes: 33.9;Spermatogonia: 22.5" "Cancer enriched" "Detected in single" 27 "testis cancer: 1.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 69 "K-562: 8.3" "HPA034699, HPA034700" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Cytosol" "HPA034699: AB_2674288, HPA034700: AB_10670159" "unprognostic (8.21e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (1.00e-1)" "unprognostic (5.54e-6)" "unprognostic (4.50e-2)" "unprognostic (1.77e-1)" "unprognostic (5.73e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.7 0.1 0.3 0.3 0.0 0.4 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 33.9 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf73 FLJ40298 ENSG00000177994 "Chromosome 2 open reading frame 73" Q8N5S3 2 54330034-54383742 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 50.6" "Group enriched" "Detected in some" 8 "Early spermatids: 1101.7;Late spermatids: 600.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "hTERT-RPE1: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055221, HPA059596" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 34: Spermatids - Unknown function" "HPA055221: AB_2682744, HPA059596: AB_2684077" "unprognostic (1.56e-2)" "unprognostic (7.00e-3)" "unprognostic (1.51e-2)" "unprognostic (1.39e-2)" "unprognostic (5.46e-2)" "unprognostic (2.74e-2)" "unprognostic (6.69e-3)" "unprognostic (2.36e-2)" "unprognostic (1.62e-3)" "unprognostic (7.69e-2)" "unprognostic (3.00e-2)" "unprognostic (5.01e-3)" "unprognostic (1.17e-2)" "unprognostic (8.99e-2)" "unprognostic (3.80e-2)" 0.1 0.6 1.9 0.0 2.1 0.0 0.1 1.6 2.0 0.5 6.4 0.1 0.0 0.3 1.3 0.0 7.6 0.0 0.1 1.9 2.1 0.6 0.0 1.1 0.0 3.8 3.4 0.3 0.6 0.9 1.4 0.0 2.5 0.3 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.0 50.6 2.0 0.0 1.1 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.1 1.6 2.0 1.9 2.1 3.8 3.4 2.5 3.2 2.0 2.3 0.7 0.0 0.0 13.7 0.0 0.3 0.4 1.8 0.0 0.3 0.5 0.9 0.1 0.0 9.7 3.7 0.0 0.0 0.0 0.0 5.9 0.2 1101.7 36.0 0.6 0.8 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.0 2.0 0.0 0.4 600.3 7.8 0.3 0.0 1.0 0.0 2.4 0.0 1.5 2.1 0.0 0.0 4.1 0.0 0.2 0.0 3.7 56.4 1.7 0.0 0.2 0.8 97.8 7.3 0.0 0.1 0.0 0.0 0.3 0.0 0.2 SPTBN1 ENSG00000115306 "Spectrin beta, non-erythrocytic 1" Q01082 2 54456317-54671446 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 615.4;Peritubular cells: 663.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012685, HPA013149" Supported Approved "Golgi apparatus" NA Yes 1500000 "Cluster 39: Non-specific - mRNA processing" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "HPA012685: AB_1857433, HPA013149: AB_1857434" "unprognostic (2.72e-1)" "unprognostic (4.44e-3)" "unprognostic (3.00e-2)" "unprognostic (3.25e-1)" "unprognostic (4.09e-2)" "unprognostic (7.95e-2)" "unprognostic (9.24e-2)" "unprognostic (3.72e-2)" "unprognostic (7.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.26e-2)" "unprognostic (7.25e-2)" "prognostic favorable (2.59e-5)" "unprognostic (2.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.68e-3)" "unprognostic (5.18e-3)" 187.3 70.9 210.6 34.7 205.1 37.6 78.7 97.4 166.1 54.1 94.2 62.8 32.7 52.0 36.3 41.7 56.2 69.2 135.9 156.2 99.7 65.3 83.8 131.6 28.9 141.2 154.4 73.2 45.5 129.2 27.8 97.4 120.4 43.8 52.4 56.0 55.1 74.4 54.0 39.4 46.8 59.9 134.8 58.7 55.6 32.6 214.6 29.3 72.8 87.2 30.0 45.6 38.6 163.6 96.5 150.5 60.4 57.2 234.7 158.8 74.8 40.2 82.3 63.7 61.4 101.7 66.6 0.4 112.1 142.0 55.1 110.9 85.1 128.0 66.0 0.8 35.6 43.7 118.4 166.2 97.7 59.7 24.4 62.3 64.8 193.8 119.7 77.6 151.6 95.1 50.0 64.0 86.1 21.6 105.0 14.5 66.3 129.6 70.2 116.2 95.0 37.2 92.2 120.6 36.3 113.3 121.5 39.5 88.1 58.9 19.6 9.9 235.2 89.9 79.0 110.2 58.2 62.8 42.8 32.7 98.1 17.7 163.7 2.3 0.4 2.8 3.7 0.0 3.9 3.7 3.4 3.6 1.3 3.5 5.0 3.6 0.6 5.2 0.0 1.1 3.2 3.1 210.6 205.1 97.4 166.1 156.2 99.7 141.2 154.4 120.4 134.8 214.6 163.6 615.4 407.1 124.6 233.4 45.7 83.1 50.0 64.7 42.7 94.4 60.8 58.0 262.9 144.4 100.6 145.3 73.0 28.3 31.7 343.6 7.9 223.7 12.1 140.4 80.3 426.4 83.1 21.5 231.3 121.9 42.0 271.6 139.7 115.7 35.4 68.2 228.5 184.6 14.2 141.3 195.4 135.5 77.3 17.7 47.0 31.5 503.2 16.6 147.7 294.2 9.7 131.9 36.0 154.8 283.1 243.3 109.9 663.5 76.3 75.6 142.8 44.1 187.3 93.6 164.3 340.3 171.9 54.7 53.3 79.7 68.2 11.1 49.2 56.6 151.9 88.1 EML6 FLJ42562 ENSG00000214595 "EMAP like 6" Q6ZMW3 2 54723499-54972025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.3;retina: 13.9" "Cell type enhanced" "Detected in many" "Astrocytes: 145.0;Excitatory neurons: 372.7;Inhibitory neurons: 265.1;Oligodendrocyte precursor cells: 95.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 10.9;SCLC-21H: 34.0;U-698: 35.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062808, HPA068759" Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Vesicles "HPA062808: AB_2684872, HPA068759: AB_2686027" "unprognostic (1.06e-1)" "unprognostic (6.89e-4)" "unprognostic (7.83e-2)" "unprognostic (9.96e-2)" "unprognostic (6.24e-2)" "unprognostic (3.26e-4)" "unprognostic (5.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (6.27e-2)" "unprognostic (6.85e-6)" "unprognostic (5.00e-1)" "unprognostic (5.81e-2)" "unprognostic (6.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (5.13e-3)" 0.3 3.0 1.6 4.0 1.8 0.7 0.7 1.4 3.8 0.2 0.2 0.7 0.7 0.3 1.1 0.5 0.4 0.2 0.1 2.2 2.1 1.7 0.5 0.4 7.0 1.3 1.4 0.1 0.8 1.9 3.2 1.4 1.3 0.6 0.8 13.9 0.5 0.5 1.0 0.9 2.0 0.4 0.6 2.6 0.5 1.3 1.4 0.6 2.6 0.5 10.3 0.6 0.4 2.9 0.7 2.0 0.2 1.5 1.0 0.3 2.0 0.2 0.3 0.2 0.2 0.8 0.3 10.9 0.2 0.7 0.4 0.3 1.4 0.5 0.4 1.0 0.4 0.6 0.9 5.1 0.0 0.3 0.0 0.1 0.1 0.6 1.1 0.2 0.2 6.2 0.0 2.0 0.0 1.1 2.1 0.4 0.5 0.2 2.3 0.9 0.7 0.8 0.1 1.4 34.0 4.2 0.5 0.1 0.0 0.2 0.1 0.1 0.3 0.4 2.1 0.5 0.6 7.8 2.2 35.0 1.8 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 1.4 3.8 2.2 2.1 1.3 1.4 1.3 0.6 1.4 2.9 0.9 0.0 1.1 145.0 7.3 3.7 1.9 0.6 1.8 28.0 1.1 0.8 2.0 0.0 3.5 3.7 56.3 0.4 0.4 0.5 0.0 0.2 24.6 2.9 0.6 1.3 2.4 0.0 372.7 0.4 0.6 1.0 2.0 1.2 0.0 0.8 1.4 0.6 1.3 38.7 265.1 3.6 0.0 1.0 2.3 11.2 0.6 0.6 0.0 19.7 0.0 14.3 1.0 95.5 30.2 0.1 0.1 0.7 8.4 1.6 1.1 0.7 7.0 32.7 0.0 2.2 1.5 5.1 2.6 0.6 4.4 0.1 0.8 0.9 0.4 2.3 RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 3547.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 95.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1801.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 3400000 "Cluster 38: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "CAB005388: AB_2285559, HPA023977: AB_2671391" "unprognostic (1.31e-2)" "unprognostic (1.71e-3)" "unprognostic (6.76e-2)" "unprognostic (1.28e-3)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.79e-2)" "unprognostic (1.84e-3)" "unprognostic (2.47e-1)" "unprognostic (1.97e-1)" "unprognostic (3.91e-3)" "unprognostic (4.38e-1)" "unprognostic (4.41e-2)" "unprognostic (1.29e-2)" "unprognostic (4.99e-2)" "unprognostic (1.27e-1)" "unprognostic (4.91e-2)" 586.2 302.7 376.3 150.9 461.9 115.4 253.1 465.9 534.3 118.0 297.1 186.9 236.2 153.9 176.5 217.9 130.0 196.8 166.0 411.8 431.6 442.5 551.9 211.8 83.6 498.6 456.5 132.0 122.7 236.7 84.0 177.3 524.8 223.9 179.2 640.6 127.1 183.4 996.0 252.9 292.5 246.4 440.8 110.3 124.0 78.6 453.2 87.1 130.7 777.9 88.2 291.2 147.9 591.2 402.9 285.3 273.3 71.7 908.4 845.0 153.2 1301.6 1097.4 393.5 365.7 235.5 371.7 87.1 673.8 889.9 657.7 355.6 181.5 524.4 596.2 248.3 139.4 120.3 159.6 376.6 1801.9 218.1 59.7 638.5 490.8 540.3 1041.9 792.3 751.3 215.6 249.8 195.0 1724.1 117.8 268.3 222.0 245.9 86.8 252.0 118.5 360.3 180.0 924.0 475.9 179.2 211.3 297.7 173.3 378.1 465.1 147.2 165.1 1074.9 764.8 326.1 304.8 756.5 118.0 103.4 56.1 778.7 247.9 630.1 95.8 9.5 27.5 9.2 11.6 7.6 6.8 14.7 8.2 9.2 3.8 24.1 10.2 15.6 41.1 19.0 13.7 37.6 9.9 376.3 461.9 465.9 534.3 411.8 431.6 498.6 456.5 524.8 440.8 453.2 591.2 451.4 176.3 203.4 201.4 102.3 1062.1 1456.6 367.0 225.9 644.6 297.6 260.6 182.0 243.1 251.0 676.8 379.5 529.6 173.6 408.6 291.6 559.7 459.7 316.6 264.6 308.0 222.1 98.2 454.5 323.4 611.9 421.9 98.4 324.7 150.4 161.5 181.3 633.4 669.1 425.7 370.4 280.5 231.9 339.0 578.4 266.6 167.4 371.7 341.5 215.5 396.4 3547.4 137.0 249.3 1334.3 571.2 309.7 226.1 81.6 921.4 897.1 678.3 233.6 540.0 216.9 420.5 324.6 382.7 90.1 247.1 1059.3 362.0 145.5 100.1 238.1 1226.5 CLHC1 "C2orf63, FLJ31438" ENSG00000162994 "Clathrin heavy chain linker domain containing 1" Q8NHS4 2 55172547-55232563 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.6;Early spermatids: 52.6;Late spermatids: 40.1;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 40.2;Respiratory ciliated cells: 44.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045418, HPA053557" Uncertain Approved "Nucleoli fibrillar center,Centrosome" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center, Centrosome" "HPA045418: AB_10962144, HPA053557: AB_2682188" "unprognostic (1.60e-1)" "unprognostic (2.86e-1)" "unprognostic (3.43e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (4.91e-2)" "unprognostic (6.41e-3)" "unprognostic (1.03e-3)" "unprognostic (1.39e-1)" "unprognostic (3.54e-4)" "unprognostic (6.36e-2)" "unprognostic (1.05e-4)" "unprognostic (1.84e-1)" "unprognostic (1.47e-1)" "unprognostic (1.19e-2)" "prognostic favorable (2.15e-4)" 2.3 2.8 2.7 1.8 3.2 2.1 3.3 6.7 3.8 3.2 11.4 2.8 2.1 4.2 5.0 2.6 4.4 3.1 2.4 3.2 2.7 3.6 1.6 2.5 2.8 4.9 5.5 3.2 2.6 5.4 5.9 3.6 3.1 4.5 3.1 7.7 2.7 3.5 1.7 4.9 2.7 3.5 3.4 3.4 2.4 15.1 3.0 4.1 3.9 1.0 2.1 2.9 2.9 4.5 3.4 2.2 6.6 3.4 2.4 3.3 5.1 4.2 3.9 2.1 1.9 4.5 2.8 4.7 2.6 1.9 2.7 5.3 2.8 3.7 4.3 4.3 3.6 7.1 7.9 4.5 2.8 4.4 3.5 4.3 3.0 2.8 6.0 6.6 2.2 4.3 3.8 2.9 2.4 2.5 3.9 4.6 2.3 1.2 1.0 3.8 3.3 3.0 3.5 4.2 6.4 4.4 2.8 4.0 4.7 4.7 2.8 2.4 5.8 5.2 3.4 2.7 3.5 5.4 1.5 2.6 4.3 4.4 1.4 0.5 0.2 1.3 0.3 0.6 0.0 0.4 0.5 0.3 0.4 0.4 0.6 0.3 0.1 0.9 0.5 0.9 0.4 0.3 2.7 3.2 6.7 3.8 3.2 2.7 4.9 5.5 3.1 3.4 3.0 4.5 3.0 0.0 4.1 35.6 2.7 1.9 5.2 7.0 4.0 12.3 3.9 3.8 4.7 1.5 9.8 3.7 16.7 3.4 1.0 2.1 5.9 3.8 52.6 19.3 7.1 3.0 7.3 2.1 18.8 1.4 1.7 5.1 3.6 4.3 0.0 13.5 5.0 0.3 2.3 10.1 27.0 1.7 4.1 4.6 0.7 40.1 4.1 3.1 1.8 15.0 2.0 9.6 2.1 48.2 40.2 1.0 1.2 5.7 1.6 3.9 1.8 3.0 44.9 19.7 0.0 3.8 3.7 29.9 2.3 3.5 2.3 3.4 2.2 7.6 2.9 4.1 RPS27A "S27A, Uba80, UBCEP80" ENSG00000143947 "Ribosomal protein S27a" P62979 2 55231903-55235853 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033319, HPA041344, HPA049132, HPA054087" Supported Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA Yes 230000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "CAB033319: AB_793618, HPA041344: AB_2677422, HPA049132: AB_2680646, HPA054087: AB_2682373" "unprognostic (7.32e-2)" "unprognostic (1.41e-2)" "unprognostic (1.11e-1)" "unprognostic (3.20e-3)" "unprognostic (2.16e-1)" "unprognostic (9.75e-2)" "prognostic unfavorable (2.26e-4)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (2.46e-1)" "unprognostic (6.89e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.09e-1)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (3.60e-1)" 1440.7 1208.5 1115.0 1077.7 1151.0 2567.0 2511.6 1098.2 1883.7 2166.1 1099.2 1563.5 823.5 1450.9 1105.1 1698.4 1726.7 572.2 943.7 1085.1 1131.6 1254.8 1162.3 1097.1 1955.6 1133.6 1117.0 3146.7 2043.5 730.2 1057.5 872.9 1131.4 1430.2 1045.0 631.9 1387.4 917.9 1089.6 1767.3 1328.6 814.7 1172.6 1719.2 1478.2 405.9 1150.4 1520.4 1201.6 793.7 1774.4 1506.3 1694.7 1157.1 2384.4 1092.2 1412.2 1842.3 1892.6 3200.3 2412.6 1824.5 1779.4 1692.3 1069.1 2073.7 1987.4 3081.3 2833.2 1698.5 1115.0 1784.3 2061.7 2465.1 1981.0 2899.1 2419.0 2693.9 1088.0 2758.1 2705.9 3674.4 1605.2 3166.1 4213.4 1280.5 3401.6 3015.5 2415.9 1959.5 2469.0 2228.9 1937.3 1509.9 2307.6 4328.7 2831.1 2690.2 1710.6 2086.4 3051.2 3173.8 1994.3 1817.4 1546.0 1319.2 1064.4 4071.8 3843.7 2065.9 1811.0 3411.1 2108.9 1351.7 2395.8 1318.7 3006.7 2322.2 1881.5 1867.9 1923.5 3226.7 1392.6 1301.5 1656.9 637.7 2924.2 1530.8 4268.2 4727.8 4504.3 3592.2 2219.0 4232.8 5675.0 4744.3 351.6 3178.7 1388.8 3292.5 3058.2 8225.2 1115.0 1151.0 1098.2 1883.7 1085.1 1131.6 1133.6 1117.0 1131.4 1172.6 1150.4 1157.1 3051.9 1272.4 2321.3 39.8 7158.8 8321.0 8963.0 6850.9 5010.5 446.4 8189.8 10987.6 438.8 3029.7 3486.3 1397.8 214.8 5340.9 5465.1 1499.3 4055.8 3640.9 1050.2 1695.4 3081.0 3385.0 2057.4 3362.1 45.8 7348.0 6754.1 3043.5 1762.0 1917.3 3014.6 3565.0 3729.5 3181.0 3498.7 218.7 47.8 3995.4 2199.2 5051.0 6045.7 1576.9 5081.5 3382.7 3639.2 59.0 6346.8 2229.4 5579.8 29.1 61.0 5045.3 3396.0 2881.2 3458.4 8189.2 3670.3 5961.1 1726.4 760.9 1643.5 5220.3 4020.2 1047.7 863.4 5750.5 8931.2 5390.3 6365.7 3721.9 4717.6 7980.9 MTIF2 IF-2mt ENSG00000085760 "Mitochondrial translational initiation factor 2" P46199 2 55236595-55269347 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006021, HPA061422" Approved Enhanced Mitochondria NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA006021: AB_2147687, HPA061422: AB_2684514" "unprognostic (2.91e-2)" "unprognostic (9.58e-2)" "unprognostic (1.52e-2)" "unprognostic (1.87e-3)" "unprognostic (8.86e-2)" "unprognostic (5.57e-2)" "unprognostic (9.76e-3)" "unprognostic (1.88e-1)" "unprognostic (6.85e-3)" "unprognostic (3.01e-2)" "unprognostic (6.58e-3)" "unprognostic (1.76e-1)" "unprognostic (3.98e-2)" "unprognostic (2.54e-2)" "unprognostic (1.66e-1)" "unprognostic (9.45e-3)" "unprognostic (1.33e-1)" 17.5 18.2 14.8 16.7 16.6 14.2 19.6 17.0 18.0 14.4 19.1 27.7 27.2 10.8 17.8 18.7 13.0 11.6 31.9 15.0 17.4 24.8 33.0 12.3 20.6 16.8 16.1 11.4 26.7 24.2 10.9 13.4 17.0 14.4 31.5 15.5 18.5 14.0 44.2 16.1 22.0 12.4 16.4 17.4 20.7 12.2 16.8 16.8 20.5 48.8 20.3 15.0 13.2 18.1 42.4 39.8 23.2 40.2 27.8 37.7 53.1 37.8 29.9 35.5 30.9 48.0 39.8 69.1 69.6 34.5 39.7 36.7 55.2 54.5 58.3 77.1 42.6 63.3 30.9 89.4 53.4 101.6 36.4 41.7 54.9 49.1 101.9 31.4 29.1 37.8 114.4 38.4 37.0 35.2 31.5 68.2 49.3 52.2 48.5 32.7 74.3 67.1 34.4 36.8 41.3 26.2 33.7 54.8 71.0 27.8 28.9 33.6 28.5 37.0 42.5 44.6 62.8 71.3 68.3 18.8 39.3 74.3 29.7 5.6 10.3 9.7 9.0 12.7 11.7 7.5 9.2 8.6 13.5 9.5 11.2 11.5 4.0 16.7 10.8 6.6 12.2 6.8 14.8 16.6 17.0 18.0 15.0 17.4 16.8 16.1 17.0 16.4 16.8 18.1 10.9 22.4 23.6 9.8 16.6 7.6 19.1 18.8 13.6 0.0 15.5 14.2 80.7 22.8 16.9 7.3 0.0 32.1 22.2 18.7 29.4 33.6 16.9 24.0 17.6 13.5 19.2 22.1 8.9 33.5 31.1 14.0 17.3 15.6 21.5 26.7 10.4 29.9 23.8 0.0 9.7 19.3 18.3 25.1 7.0 18.2 9.0 19.0 8.8 12.2 35.5 0.0 21.6 8.5 13.6 29.8 15.3 10.5 21.5 11.8 26.3 25.7 22.5 0.0 6.6 14.0 20.6 30.1 17.8 20.3 7.4 16.3 13.3 29.0 33.3 15.1 CCDC88A "APE, FLJ10392, GIV, GRDN, HkRP1, KIAA1212" ENSG00000115355 "Coiled-coil domain containing 88A" Q3V6T2 2 55287842-55419895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA replication, Neurogenesis" "Guanine-nucleotide releasing factor" "Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in many" "Early spermatids: 634.4;Late spermatids: 699.8;Oligodendrocytes: 754.9;Spermatocytes: 429.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 7.4;classical monocyte: 7.2;intermediate monocyte: 7.0;myeloid DC: 11.3;non-classical monocyte: 6.8;plasmacytoid DC: 23.9" "Group enriched" "Detected in all" 7 "dendritic cells: 23.9;granulocytes: 7.4;monocytes: 7.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038101, HPA038102" Enhanced NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA038101: AB_10670654, HPA038102: AB_2675833" "unprognostic (1.20e-1)" "unprognostic (2.86e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.06e-4)" "unprognostic (1.91e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.86e-4)" "unprognostic (8.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (3.18e-3)" "unprognostic (1.71e-1)" "prognostic unfavorable (5.98e-8)" "unprognostic (1.42e-2)" "unprognostic (2.61e-1)" "unprognostic (5.74e-3)" "unprognostic (8.96e-3)" 11.4 9.7 48.4 14.0 65.3 15.6 8.4 53.2 77.6 8.7 29.6 9.6 3.8 9.8 3.3 5.4 7.5 7.7 9.2 48.8 54.4 4.7 8.4 14.5 17.2 54.8 60.8 9.3 10.7 3.4 13.2 8.3 57.7 5.9 5.2 26.3 6.7 5.4 7.3 4.2 7.1 9.3 48.8 13.3 6.5 47.3 62.6 18.8 5.8 9.6 15.1 9.6 6.2 80.9 22.8 19.7 45.2 18.3 29.4 24.3 4.0 32.3 30.1 18.9 20.6 2.1 12.0 60.2 19.5 32.6 28.9 0.4 28.9 19.3 46.8 69.8 16.8 41.4 21.7 28.6 12.6 70.7 26.8 15.8 3.8 44.6 28.6 27.1 50.3 48.1 44.9 95.9 51.9 0.2 33.5 41.1 37.4 0.3 24.8 39.7 71.1 0.3 22.9 12.1 23.5 34.8 57.4 0.1 28.9 26.2 1.1 20.2 34.9 54.4 36.5 36.6 39.6 28.8 24.0 25.8 38.0 56.2 23.7 7.4 7.2 2.1 1.4 7.0 0.8 1.8 0.6 1.1 11.3 0.6 0.7 0.6 0.6 1.2 6.8 23.9 0.3 2.1 48.4 65.3 53.2 77.6 48.8 54.4 54.8 60.8 57.7 48.8 62.6 80.9 35.6 12.8 27.9 197.9 25.5 8.4 7.4 11.2 9.1 225.1 7.2 11.9 52.8 4.3 12.8 5.5 37.5 6.5 90.5 0.2 1.9 4.2 634.4 8.0 58.8 41.0 10.8 51.3 317.1 16.8 18.4 38.1 9.2 3.1 152.8 64.4 22.1 18.5 110.8 79.1 318.9 0.0 4.1 142.0 126.7 699.8 29.8 184.2 16.0 129.3 236.1 109.8 11.3 296.6 754.9 31.1 0.2 28.6 114.7 2.9 0.0 8.1 10.1 61.9 32.9 45.1 55.4 429.0 95.5 5.9 6.5 2.3 22.4 82.3 0.1 2.8 CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1342.4;Late spermatids: 262.5;Spermatocytes: 346.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli fibrillar center, Nuclear bodies" Cytosol "HPA008994: AB_2275429, HPA017061: AB_1846129" "unprognostic (8.11e-2)" "unprognostic (3.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.36e-2)" "unprognostic (7.98e-2)" "unprognostic (3.68e-1)" "unprognostic (4.65e-3)" "unprognostic (7.79e-2)" "unprognostic (1.51e-2)" "unprognostic (1.58e-2)" "unprognostic (3.66e-3)" "unprognostic (7.63e-2)" "unprognostic (8.57e-3)" "unprognostic (4.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-3)" "unprognostic (2.96e-1)" 39.1 42.7 72.7 20.2 74.8 16.5 48.9 61.8 98.8 49.8 82.8 52.3 15.1 47.1 77.0 21.9 62.3 40.9 35.7 75.0 78.5 63.2 17.7 33.9 21.7 71.8 70.4 58.9 33.6 78.0 106.7 20.6 72.1 41.6 23.2 124.3 28.7 45.0 19.2 18.8 25.2 37.4 65.9 18.2 42.1 145.2 73.6 22.8 78.0 27.1 19.7 40.7 33.6 70.1 59.5 47.3 50.2 66.3 64.4 119.4 30.4 36.6 73.4 54.9 46.6 34.6 21.2 21.3 82.3 48.9 81.9 38.4 39.3 51.4 67.7 51.9 76.2 31.0 43.9 38.1 70.0 59.4 38.4 58.1 82.7 74.0 92.1 146.8 58.9 42.5 40.1 18.2 66.1 44.4 35.7 67.5 25.2 38.7 44.8 27.2 59.7 21.7 112.1 33.7 74.1 36.6 49.4 25.6 68.5 26.2 42.1 19.7 32.5 57.6 33.7 58.5 50.8 29.9 14.2 7.3 94.0 26.7 26.8 15.5 4.3 13.6 18.3 5.0 35.4 16.9 50.6 29.6 5.8 11.7 41.1 26.0 5.2 12.3 6.4 13.5 30.5 15.9 72.7 74.8 61.8 98.8 75.0 78.5 71.8 70.4 72.1 65.9 73.6 70.1 51.3 48.1 30.6 15.7 14.5 0.0 52.6 0.0 22.2 39.6 48.7 77.2 37.9 38.6 27.2 35.0 8.4 14.3 14.8 6.4 92.0 61.9 1342.4 184.4 51.8 42.9 17.0 21.0 51.6 60.7 27.0 44.7 21.9 36.3 39.1 27.1 42.1 10.7 23.6 23.5 41.1 12.2 0.0 8.7 0.0 262.5 75.2 12.8 0.0 14.0 16.9 145.0 16.5 21.6 13.3 37.0 11.5 67.7 11.4 41.3 7.6 146.9 99.1 92.4 59.2 43.0 43.4 346.0 29.8 16.1 0.0 7.8 24.7 36.0 9.9 35.6 PPP4R3B "FLFL2, FLJ31474, KIAA1387, PSY2, SMEK2" ENSG00000275052 "Protein phosphatase 4 regulatory subunit 3B" Q5MIZ7 2 55547292-55618880 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001233, CAB017185" Approved Supported "Nucleoplasm,Nuclear speckles,Centrosome" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Centrosome "CAB017185: , HPA001233: AB_1080033" "unprognostic (9.60e-2)" "unprognostic (2.47e-2)" "unprognostic (5.77e-2)" "unprognostic (1.87e-2)" "unprognostic (6.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.66e-2)" "unprognostic (3.27e-2)" "unprognostic (8.27e-3)" "unprognostic (7.62e-2)" "unprognostic (1.07e-2)" "unprognostic (3.69e-1)" "prognostic unfavorable (6.03e-4)" "unprognostic (9.73e-2)" "unprognostic (1.45e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" 29.0 27.4 14.8 28.2 15.1 25.8 29.1 20.9 16.9 26.8 20.0 28.1 31.6 23.7 19.3 31.7 32.3 24.7 14.3 13.8 16.9 33.4 48.0 23.4 38.1 15.0 16.3 25.7 32.1 27.4 12.5 24.5 16.2 24.9 27.7 35.3 28.1 23.2 14.7 29.6 32.1 21.8 15.9 28.7 30.8 23.7 15.1 42.2 33.0 20.3 38.7 26.7 16.9 18.7 42.8 33.0 35.6 30.0 37.2 38.9 49.1 34.0 35.9 28.2 24.0 39.5 40.9 57.7 67.5 32.7 44.8 36.4 39.9 27.5 41.4 84.6 16.7 56.7 30.0 52.9 60.3 66.0 45.6 29.8 64.9 34.1 60.1 36.9 45.0 31.6 55.2 57.4 37.7 50.9 42.8 43.7 35.1 55.9 25.3 40.1 53.6 44.6 39.3 43.8 43.4 26.9 36.8 49.9 54.8 23.5 31.6 52.0 36.3 43.3 56.8 21.6 47.2 59.1 47.3 22.3 40.8 61.3 47.2 25.6 16.5 26.9 20.4 20.9 23.2 18.1 21.2 21.6 18.4 18.6 24.5 21.5 19.6 22.5 23.0 9.9 24.0 23.9 14.8 15.1 20.9 16.9 13.8 16.9 15.0 16.3 16.2 15.9 15.1 18.7 46.8 44.8 41.3 0.0 61.8 0.0 48.9 0.0 44.3 44.1 42.7 27.9 0.0 31.5 29.1 16.5 33.3 30.6 51.4 25.3 39.2 32.4 9.5 85.1 43.2 32.9 18.2 46.7 0.0 41.0 28.5 33.9 43.8 39.6 30.3 39.0 26.0 52.5 26.2 53.8 0.0 29.4 0.0 37.7 0.0 7.6 28.0 44.9 0.0 0.0 47.9 53.1 49.4 0.0 0.0 35.4 24.1 36.1 57.2 57.4 46.1 52.9 62.7 38.5 6.6 54.9 28.4 39.1 25.7 53.3 0.0 47.7 56.3 44.6 29.0 57.2 PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634061-55693863 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease variant, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033424, HPA034602, HPA034603" Supported Supported Mitochondria,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria Cytosol "CAB033424: AB_2299801, HPA034602: AB_2674243, HPA034603: AB_10603130" "unprognostic (9.09e-2)" "unprognostic (7.40e-2)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (3.40e-2)" "unprognostic (1.03e-2)" "prognostic unfavorable (1.95e-7)" "unprognostic (1.88e-1)" "unprognostic (5.93e-3)" "unprognostic (5.23e-2)" "prognostic unfavorable (5.44e-5)" "unprognostic (2.19e-2)" "unprognostic (2.11e-2)" "unprognostic (6.92e-2)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (1.21e-1)" 6.7 5.9 5.4 4.0 7.0 7.4 5.7 6.4 7.7 5.2 6.4 5.7 3.3 6.4 4.5 4.6 5.7 3.0 6.6 4.8 6.5 5.6 5.2 5.0 4.3 6.9 6.0 4.8 7.8 4.9 5.0 2.9 7.1 4.4 5.2 5.5 5.0 3.2 11.5 5.9 5.3 4.2 5.7 6.2 5.8 3.2 6.3 3.4 5.2 5.9 3.3 5.6 4.5 9.0 9.0 4.3 6.5 2.9 4.7 7.8 8.4 12.2 7.7 19.8 13.1 13.5 4.2 17.9 5.4 5.8 6.2 7.1 8.3 10.1 9.5 6.3 16.3 10.2 5.9 7.0 11.8 25.0 6.4 8.6 6.9 8.4 7.0 4.7 6.4 7.3 11.5 4.2 8.0 4.4 15.4 17.9 15.5 9.3 8.1 15.2 10.9 16.6 8.6 5.2 15.2 9.6 4.4 14.3 17.0 5.6 3.8 11.4 6.4 4.6 3.9 4.2 13.5 18.9 1.3 3.8 9.2 21.1 8.3 3.3 3.4 4.0 4.2 2.8 2.4 3.1 1.7 4.1 1.3 5.6 3.4 3.9 3.4 2.2 2.7 4.1 1.4 2.9 5.4 7.0 6.4 7.7 4.8 6.5 6.9 6.0 7.1 5.7 6.3 9.0 25.1 48.1 57.0 23.8 21.6 24.2 23.1 17.5 29.0 41.3 12.6 11.2 25.6 15.7 46.8 20.2 58.4 19.9 14.2 7.7 9.8 18.6 25.6 27.9 28.9 24.4 10.2 17.4 48.4 16.0 23.3 25.3 14.8 14.3 58.7 21.8 11.7 14.7 15.4 30.3 48.1 12.8 26.4 12.2 17.7 4.8 17.4 26.7 16.0 17.8 16.5 23.9 13.4 34.2 97.7 15.8 11.4 18.4 23.1 26.0 7.6 19.8 38.5 58.6 26.3 31.7 22.3 43.4 20.7 25.7 20.2 12.3 24.7 58.2 18.6 17.6 EFEMP1 "DHRD, FBLN3, FBNL, MTLV, S1-5" ENSG00000115380 "EGF containing fibulin extracellular matrix protein 1" Q12805 2 55865967-55924139 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 367.7;Cytotrophoblasts: 1365.8;Fibroblasts: 309.7;Syncytiotrophoblasts: 889.6" "Cancer enhanced" "Detected in all" "glioma: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 953.6;hTERT-RPE1: 2226.5;HUVEC TERT2: 4270.9;TIME: 3554.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016368, HPA049806, HPA070841, HPA071588" Supported Supported Mitochondria "Secreted to extracellular matrix" NA NA 1900000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "CAB016368: AB_2277777, HPA049806: , HPA070841: AB_2686319, HPA071588: " "unprognostic (8.21e-2)" "unprognostic (7.68e-2)" "unprognostic (9.01e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (3.43e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (9.07e-2)" "unprognostic (1.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.89e-8)" "unprognostic (3.15e-3)" "unprognostic (4.94e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (6.68e-5)" 240.5 55.7 57.0 57.2 82.8 0.2 115.3 57.1 88.8 54.9 180.7 74.6 22.5 73.2 128.4 51.5 134.8 140.4 187.8 47.5 75.6 57.4 12.9 150.1 27.2 80.8 121.1 175.1 29.2 17.6 22.6 329.7 65.5 58.4 91.0 42.8 87.7 161.2 14.7 55.2 45.3 93.5 72.2 42.4 46.9 8.0 71.0 16.8 139.1 93.8 21.2 203.9 77.3 71.9 358.4 3.1 8.5 0.3 320.9 217.1 0.8 208.1 233.7 25.2 20.5 0.0 18.0 0.5 140.4 234.3 22.1 323.4 1.6 234.6 8.9 1.0 1.0 0.3 87.4 0.2 843.2 0.3 0.6 953.6 117.5 21.9 260.9 2226.5 4270.9 0.5 1.2 0.2 99.2 36.7 2.6 0.5 4.2 0.1 0.8 0.2 0.3 0.9 9.8 7.3 2.0 0.4 284.6 105.0 0.7 8.1 289.8 1.5 3554.3 1.5 107.5 397.9 138.5 13.7 0.5 1.4 73.1 0.3 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.0 82.8 57.1 88.8 47.5 75.6 80.8 121.1 65.5 72.2 71.0 71.9 26.6 250.0 109.1 234.1 0.1 79.4 79.1 367.7 42.1 2.8 6.2 78.2 12.5 12.8 98.2 27.6 0.0 1365.8 0.4 0.0 9.8 36.2 0.5 2.2 38.9 73.5 0.0 0.0 1.0 25.6 173.0 309.7 6.1 2.1 2.5 3.9 48.5 0.7 94.9 0.0 4.7 0.0 40.7 0.8 33.9 0.9 42.6 3.2 17.8 6.5 0.6 137.3 0.0 2.5 0.8 2.8 0.0 0.0 1.5 24.2 0.0 14.7 88.8 4.7 0.0 7.0 28.7 0.4 1.8 6.0 31.7 889.6 5.0 61.3 0.0 6.2 CCDC85A KIAA1912 ENSG00000055813 "Coiled-coil domain containing 85A" Q96PX6 2 56183990-56386172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.3" "Cell type enhanced" "Detected in some" "Adipocytes: 57.7;Excitatory neurons: 228.7;Inhibitory neurons: 160.5;Microglial cells: 60.0" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 45.9;fHDF/TERT166: 74.5;U-266/70: 32.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043106, HPA057020" Uncertain "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043106: AB_10794770, HPA057020: AB_2683311" "unprognostic (2.29e-1)" "unprognostic (1.28e-1)" "unprognostic (6.87e-2)" "unprognostic (3.66e-2)" "unprognostic (7.87e-2)" "unprognostic (7.62e-2)" "unprognostic (3.07e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-2)" "unprognostic (2.94e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-1)" "unprognostic (6.55e-5)" "unprognostic (3.28e-2)" "unprognostic (1.00e-1)" "unprognostic (2.88e-2)" "unprognostic (1.83e-2)" 12.5 0.6 5.4 0.6 7.4 0.0 3.5 1.2 8.0 2.5 0.0 0.7 0.3 6.3 0.8 0.7 2.1 1.2 4.5 6.9 7.2 1.0 0.1 5.5 0.5 17.3 6.5 0.5 0.7 1.3 0.2 10.0 7.0 2.0 0.7 4.0 1.2 2.7 5.4 1.7 0.4 4.7 11.8 0.7 0.5 0.4 5.1 0.6 9.1 7.5 0.6 0.7 0.7 15.2 0.0 0.8 0.1 0.0 13.9 0.8 0.0 11.6 1.1 9.8 0.9 0.0 0.1 45.9 1.7 74.5 0.0 2.0 0.0 0.0 5.6 0.0 0.3 0.0 0.6 0.0 0.7 0.0 0.1 3.3 0.3 0.0 1.2 5.5 9.7 0.0 0.0 6.1 1.3 0.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 1.7 1.3 0.0 0.3 0.1 0.0 2.1 5.3 0.0 15.3 7.9 2.3 0.1 0.9 32.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 7.4 1.2 8.0 6.9 7.2 17.3 6.5 7.0 11.8 5.1 15.2 57.7 25.6 0.6 15.3 0.8 3.3 0.5 0.0 0.0 7.8 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.3 3.6 0.2 1.9 14.8 1.2 0.0 228.7 0.4 0.1 3.7 0.0 0.5 0.0 0.2 8.6 0.0 2.3 0.0 160.5 0.2 0.0 0.3 2.0 11.9 0.3 0.3 5.4 60.0 0.0 0.7 0.0 33.7 7.2 0.7 0.1 0.0 0.1 0.3 0.0 0.3 0.0 1.5 0.0 10.0 2.7 0.2 0.8 0.1 1.3 0.1 0.1 3.6 0.9 0.3 VRK2 ENSG00000028116 "VRK serine/threonine kinase 2" Q86Y07 2 57907629-58159920 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 540.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046459, HPA047503" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "CAB046459: AB_1858773, HPA047503: AB_2680071" "unprognostic (1.87e-1)" "unprognostic (5.84e-2)" "unprognostic (4.65e-2)" "unprognostic (1.33e-3)" "unprognostic (1.27e-1)" "unprognostic (1.60e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (3.90e-2)" "unprognostic (4.76e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (3.48e-1)" "unprognostic (1.62e-1)" "unprognostic (2.99e-1)" "unprognostic (3.56e-1)" 14.8 13.2 14.9 20.2 26.4 18.8 17.2 15.1 16.2 10.8 9.3 14.0 10.9 15.3 16.7 19.5 13.4 11.9 15.6 12.8 16.0 10.7 16.8 15.9 22.5 23.9 21.1 10.7 19.7 14.7 7.6 14.6 23.0 14.2 16.4 4.8 13.8 11.4 14.3 13.3 11.0 19.4 14.8 18.0 13.7 13.3 18.9 12.7 18.6 15.1 26.0 14.7 12.6 40.6 37.1 24.3 2.7 16.3 16.7 30.6 48.4 32.8 33.3 22.7 22.9 49.8 38.5 44.3 43.0 29.8 37.1 27.4 34.9 36.7 33.7 80.9 23.1 50.9 19.0 35.8 27.8 44.1 29.0 17.7 42.6 36.3 52.8 26.1 64.9 6.2 50.2 28.5 38.2 21.2 0.3 32.9 29.9 56.9 11.6 49.4 12.0 30.6 36.8 30.2 9.4 0.3 52.5 31.2 27.5 26.2 22.0 26.1 37.0 0.5 74.4 20.6 0.6 40.5 33.9 24.0 18.2 52.7 38.4 31.0 24.5 35.3 15.1 32.2 18.4 30.6 14.2 17.7 25.5 31.7 10.6 13.6 9.0 18.7 34.3 26.4 18.5 15.4 14.9 26.4 15.1 16.2 12.8 16.0 23.9 21.1 23.0 14.8 18.9 40.6 17.9 22.4 11.2 1.3 26.4 9.8 12.6 21.8 14.8 1.0 14.0 10.2 21.8 7.2 22.4 18.4 0.0 21.2 13.7 6.5 15.6 27.1 23.0 12.7 10.9 15.8 6.6 39.1 2.7 26.2 21.1 14.0 16.3 12.7 17.7 9.6 8.9 8.4 18.4 0.0 4.7 5.1 30.5 19.1 19.1 8.4 5.9 26.2 10.6 54.4 41.7 5.3 16.5 32.2 540.8 24.8 8.7 6.0 25.7 18.4 2.5 9.5 30.7 4.0 6.6 7.4 14.3 22.0 10.9 19.2 8.4 19.4 16.5 6.8 7.9 16.4 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 8.5 35.3 39.4 11.0 49.5 15.1 19.5 35.3 39.4 18.6 27.2 12.1 11.5 19.9 18.4 11.5 13.9 12.0 13.0 34.1 45.1 12.2 21.7 9.6 14.8 51.6 40.3 24.8 14.5 14.0 44.3 12.5 55.4 14.7 14.8 24.6 18.7 10.7 9.1 17.9 12.8 13.5 40.9 16.8 13.1 19.1 41.2 13.2 17.1 9.1 12.6 11.7 14.6 68.6 48.6 35.0 69.4 34.0 11.9 15.1 36.9 34.8 21.5 33.8 43.5 30.9 59.4 33.4 43.8 11.4 46.3 27.5 39.0 26.4 56.0 78.8 61.7 54.8 49.5 42.1 13.0 53.3 29.0 11.8 12.4 24.8 9.7 29.9 27.0 23.5 51.9 29.6 23.2 24.6 18.9 65.8 75.2 77.4 7.2 35.2 52.5 26.1 29.9 47.2 78.1 39.3 49.5 20.2 33.8 37.0 18.7 35.4 15.9 30.0 45.0 22.3 39.0 30.4 20.6 19.7 63.7 35.7 46.6 3.2 3.0 4.9 3.7 5.6 3.0 9.1 3.2 4.2 5.9 9.3 1.0 2.3 0.8 7.6 4.3 5.3 4.8 2.2 39.4 49.5 35.3 39.4 34.1 45.1 51.6 40.3 55.4 40.9 41.2 68.6 16.7 19.2 20.0 18.6 9.4 10.3 13.9 26.1 11.4 16.6 12.5 15.4 16.4 8.6 16.1 9.2 4.2 29.1 4.8 7.2 11.7 9.7 2.5 11.1 15.8 14.8 9.0 14.5 45.0 4.2 14.0 12.2 15.3 6.2 10.8 25.8 13.2 12.5 10.9 8.4 38.4 15.0 30.5 6.3 4.6 3.6 10.8 7.0 26.6 34.7 6.8 22.8 3.1 81.4 188.9 4.6 13.3 14.3 9.7 6.2 21.7 5.7 23.2 18.7 13.1 10.8 12.4 52.6 37.9 9.5 6.8 7.4 5.6 13.2 16.0 9.3 BCL11A "BCL11A-L, BCL11A-S, BCL11A-XL, CTIP1, EVI9, HBFQTL5, ZNF856" ENSG00000119866 "BAF chromatin remodeling complex subunit BCL11A" Q9H165 2 60450520-60554467 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.8;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "B-cells: 149.0;Basal squamous epithelial cells: 118.4;dendritic cells: 140.3;Excitatory neurons: 180.8;Inhibitory neurons: 153.2;Squamous epithelial cells: 120.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 312.7;naive B-cell: 415.7;plasmacytoid DC: 899.0" "Group enriched" "Detected in all" 15 "B-cells: 415.7;dendritic cells: 899.0" "Cell line enhanced" "Detected in many" "Daudi: 51.1;MOLT-4: 49.0;REH: 48.3;U-698: 106.7;U-937: 34.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 52.5;cerebral cortex: 82.3;hippocampal formation: 69.2;olfactory bulb: 66.7" "CAB014891, HPA029003, HPA075941" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Nuclear bodies" "CAB014891: , HPA029003: AB_2672863, HPA075941: " "unprognostic (4.10e-3)" "unprognostic (6.72e-2)" "unprognostic (4.50e-2)" "unprognostic (9.41e-3)" "unprognostic (2.37e-1)" "unprognostic (4.47e-3)" "unprognostic (2.53e-2)" "unprognostic (1.68e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-1)" "unprognostic (4.27e-4)" "unprognostic (1.23e-2)" "unprognostic (2.35e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-1)" "unprognostic (4.40e-2)" "unprognostic (2.99e-2)" 0.7 2.1 31.4 11.3 34.7 25.3 7.1 10.5 47.8 5.2 9.7 18.4 9.7 2.1 1.4 18.4 5.7 2.5 8.0 38.7 15.5 1.0 0.5 2.1 29.2 31.6 15.3 0.6 10.8 1.7 3.0 0.9 31.0 7.8 6.1 1.7 13.8 1.9 1.7 33.2 13.9 3.4 15.9 19.6 4.8 2.0 15.9 33.9 2.3 0.2 40.9 3.3 11.5 38.7 0.6 0.0 4.2 0.1 0.8 0.8 0.3 1.5 0.0 0.1 0.0 0.0 0.2 51.1 0.2 0.2 0.0 10.5 15.4 7.4 0.2 0.9 15.2 0.1 0.6 0.2 0.0 18.7 0.1 1.7 4.1 0.0 2.5 4.0 2.6 17.1 0.8 0.3 0.1 0.1 49.0 19.9 28.6 7.7 0.2 48.3 1.3 19.7 0.0 0.9 20.1 4.8 0.3 0.4 0.3 8.0 0.3 9.1 1.0 0.3 11.6 0.3 0.1 0.8 0.2 106.7 0.1 34.0 1.6 4.5 23.8 5.1 0.5 44.1 1.1 312.7 0.5 0.5 89.9 415.7 1.3 1.1 11.0 8.4 33.7 899.0 1.1 11.4 31.4 34.7 10.5 47.8 38.7 15.5 31.6 15.3 31.0 15.9 15.9 38.7 0.6 0.0 7.4 3.6 149.0 46.3 16.0 34.0 118.4 2.5 31.6 28.6 18.2 4.3 11.7 1.8 0.0 0.6 140.3 7.5 5.9 9.5 12.0 3.9 2.0 1.4 19.8 69.6 180.8 6.4 0.5 3.6 5.1 4.8 10.1 67.4 0.7 0.1 43.2 52.2 153.2 13.6 6.1 7.0 86.1 5.0 0.3 20.5 16.0 11.2 16.0 0.3 0.0 3.5 4.6 4.7 12.5 0.0 6.0 11.7 16.2 0.5 5.5 0.3 0.0 0.2 2.0 2.9 6.9 120.3 69.9 0.8 4.6 1.0 28.9 5.8 PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756253-60802086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017795, HPA035349, HPA035350" Approved Enhanced Nucleoplasm No No "Cluster 38: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB017795: , HPA035349: AB_2674583, HPA035350: AB_2674584" "unprognostic (1.83e-1)" "unprognostic (1.06e-1)" "unprognostic (2.14e-1)" "unprognostic (3.39e-2)" "unprognostic (5.56e-2)" "unprognostic (3.54e-1)" "unprognostic (6.72e-4)" "unprognostic (2.49e-1)" "unprognostic (6.97e-3)" "unprognostic (6.83e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (2.62e-2)" 3.7 3.0 2.2 2.2 2.3 1.4 3.4 3.2 3.1 4.2 1.7 3.2 1.3 4.1 1.2 3.5 3.2 1.4 3.1 2.3 2.3 2.5 2.3 3.2 3.0 2.5 2.1 4.9 3.5 1.7 3.1 2.0 2.5 2.6 1.5 4.0 3.8 1.2 4.2 3.7 3.6 1.5 1.9 4.1 3.4 3.5 2.6 3.7 6.2 1.7 2.5 3.2 4.1 3.0 1.8 1.5 3.4 2.0 3.1 3.7 2.4 1.5 1.9 1.4 1.2 2.4 1.3 2.6 1.7 1.3 1.4 2.8 3.7 1.8 2.3 4.0 2.1 4.0 1.7 1.7 1.9 4.4 2.4 2.2 2.5 1.7 3.7 2.9 2.6 2.6 3.2 1.9 1.4 1.4 5.0 3.6 5.3 2.9 1.1 3.4 4.9 2.7 1.9 1.4 1.6 2.4 2.2 2.7 1.9 3.2 1.3 2.7 2.4 1.8 1.8 1.3 1.7 2.4 1.5 5.4 2.2 4.8 1.4 3.7 0.8 1.5 1.3 1.0 1.7 1.1 1.2 1.2 0.7 1.4 1.7 1.5 2.2 1.4 1.2 0.8 2.2 0.8 2.2 2.3 3.2 3.1 2.3 2.3 2.5 2.1 2.5 1.9 2.6 3.0 11.5 12.8 12.2 13.1 13.9 12.5 13.5 4.6 12.0 6.8 8.4 8.6 7.9 7.2 8.8 9.2 25.0 6.0 21.0 6.9 3.9 4.8 4.7 6.1 13.2 10.9 2.4 13.3 29.5 4.3 4.6 11.0 6.6 6.6 13.3 14.6 11.7 5.0 7.4 5.0 24.8 5.7 10.2 10.4 22.7 4.3 7.5 17.8 12.4 25.3 12.0 5.1 8.2 19.1 22.1 4.9 6.0 8.6 12.7 15.4 4.3 3.5 7.1 10.3 26.3 9.3 11.3 30.3 17.3 13.2 15.9 8.8 20.8 10.6 4.0 16.2 REL "c-Rel, I-Rel" ENSG00000162924 "REL proto-oncogene, NF-kB subunit" Q04864 2 60881521-60931612 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.4" "Cell type enhanced" "Detected in all" "Langerhans cells: 2061.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 61.2;U-698: 109.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB004404 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "CAB004404: AB_670194" "unprognostic (2.77e-1)" "unprognostic (2.05e-2)" "unprognostic (8.26e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-1)" "unprognostic (4.41e-2)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (2.15e-1)" "unprognostic (5.87e-2)" "unprognostic (4.38e-2)" "unprognostic (4.37e-1)" "unprognostic (2.82e-2)" "unprognostic (2.91e-2)" "unprognostic (3.53e-1)" "unprognostic (3.85e-1)" "unprognostic (3.66e-2)" 4.8 4.5 2.2 14.1 1.8 37.4 5.5 8.6 4.2 4.6 0.4 4.6 4.7 5.7 2.7 6.0 3.2 8.2 2.2 2.1 2.9 3.4 7.3 6.7 15.8 3.0 1.7 5.0 5.0 6.2 1.9 5.5 2.3 4.1 4.9 9.8 4.6 2.7 2.4 8.3 5.2 3.5 0.5 11.1 5.8 3.5 2.4 9.2 4.1 2.5 16.3 13.1 3.3 3.4 7.2 3.8 3.4 4.5 2.7 2.6 7.3 2.5 3.2 1.8 2.1 3.2 6.0 61.2 6.4 2.2 4.6 7.7 5.3 3.9 4.0 7.0 5.0 6.3 6.5 3.5 1.5 13.3 7.1 2.3 10.1 4.6 7.0 3.0 4.8 6.6 7.6 4.3 1.7 4.0 9.1 5.6 4.2 5.0 1.8 12.0 8.8 2.7 2.8 24.5 3.3 3.5 6.4 7.9 2.3 5.0 4.6 5.5 5.6 5.0 6.0 3.5 3.8 5.4 2.8 109.7 3.0 10.9 2.7 3.4 4.1 2.6 2.8 4.5 2.0 5.9 1.5 2.2 3.5 7.9 1.0 2.1 5.0 2.9 5.7 3.1 1.9 2.3 2.2 1.8 8.6 4.2 2.1 2.9 3.0 1.7 2.3 0.5 2.4 3.4 67.5 320.5 325.8 8.1 430.2 517.6 123.3 69.4 194.6 82.0 95.3 58.5 5.0 48.6 165.0 51.5 85.5 29.0 469.7 59.0 3.9 31.7 4.2 150.5 79.5 103.5 42.5 37.0 16.3 29.4 58.5 97.3 96.4 300.1 412.1 82.4 30.0 19.1 51.7 58.9 16.7 49.1 46.8 141.5 2061.4 3.4 15.5 463.9 135.2 42.2 451.1 21.3 145.2 8.5 9.2 35.1 46.6 23.7 119.5 99.7 34.3 7.7 153.1 56.2 13.1 65.9 73.9 51.5 38.4 158.0 463.1 77.6 303.7 21.3 50.1 260.6 PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: AB_2679066, HPA049582: AB_2680824" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (3.49e-2)" "unprognostic (2.44e-4)" "unprognostic (1.77e-1)" "unprognostic (1.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.72e-2)" "unprognostic (2.90e-2)" "unprognostic (8.21e-2)" "unprognostic (3.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-4)" "unprognostic (1.07e-1)" "unprognostic (6.60e-2)" "unprognostic (9.45e-2)" "unprognostic (1.15e-3)" 3.6 3.7 2.7 4.1 2.7 5.1 5.4 2.9 3.4 3.0 3.2 3.6 7.5 3.3 6.4 2.7 3.7 4.1 3.7 2.7 2.5 4.8 15.0 4.9 6.8 2.7 2.6 4.8 4.0 3.9 2.9 3.2 3.0 4.8 4.4 3.9 3.8 2.6 3.1 4.9 9.3 2.7 2.9 4.8 3.4 4.5 2.9 4.5 6.9 1.8 6.8 2.6 1.6 3.6 3.2 1.7 4.9 8.4 4.1 4.6 5.3 6.1 5.5 6.0 5.6 4.8 4.4 12.8 6.3 3.4 5.4 4.2 5.7 4.9 7.4 10.0 2.9 9.0 2.5 15.9 7.6 10.6 5.8 5.3 6.0 4.2 9.4 7.7 7.9 9.1 9.2 6.4 4.6 2.7 8.0 8.7 4.4 3.0 3.5 7.7 6.6 4.7 4.3 6.3 2.8 3.9 5.0 9.7 9.9 3.5 3.4 6.3 5.9 5.7 4.6 3.9 4.7 8.1 3.8 23.6 5.0 6.8 6.5 9.1 1.2 1.1 2.3 1.3 2.5 3.0 1.4 1.6 0.9 1.7 1.7 1.9 2.3 3.1 4.8 3.0 1.0 1.1 2.7 2.7 2.9 3.4 2.7 2.5 2.7 2.6 3.0 2.9 2.9 3.6 6.6 0.0 14.3 20.5 6.8 2.4 3.5 3.3 1.8 6.6 5.9 2.8 5.1 1.5 4.3 3.7 0.0 7.0 8.1 11.9 7.9 3.7 1.6 6.2 4.3 5.8 1.2 5.9 28.3 5.1 4.7 3.1 5.1 8.5 0.0 9.9 4.6 16.3 5.8 1.7 21.7 2.5 4.1 5.7 2.1 1.8 3.1 4.6 1.8 14.0 9.0 7.0 7.2 19.1 24.4 3.5 3.0 1.5 4.6 3.8 26.7 6.3 7.7 7.1 6.6 3.1 3.0 13.9 13.4 3.9 2.3 12.4 6.6 8.2 4.5 10.6 PEX13 ENSG00000162928 "Peroxisomal biogenesis factor 13" Q92968 2 61017225-61051990 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 125.8;Urothelial cells: 112.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032141, HPA032142, CAB032689" Enhanced Supported Peroxisomes NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Peroxisomes "CAB032689: AB_2162137, HPA032141: AB_2674176, HPA032142: AB_10669676" "unprognostic (2.44e-3)" "unprognostic (4.10e-2)" "unprognostic (7.84e-3)" "unprognostic (2.73e-2)" "unprognostic (1.28e-1)" "unprognostic (5.08e-2)" "unprognostic (2.05e-2)" "unprognostic (1.78e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (5.42e-2)" "unprognostic (4.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.84e-1)" "unprognostic (1.41e-1)" "unprognostic (2.63e-2)" 9.5 8.0 6.6 6.7 7.1 7.4 11.1 9.7 9.2 10.2 10.2 10.2 10.2 9.2 7.5 10.2 6.6 8.8 11.9 6.8 7.4 13.6 25.0 9.3 6.8 6.7 7.1 11.0 11.8 9.6 7.4 9.3 6.8 14.6 10.7 8.8 8.7 5.8 14.6 7.9 9.8 8.1 6.6 6.7 10.1 14.9 7.1 7.3 13.7 13.6 6.7 13.8 9.1 7.7 15.5 11.3 15.7 20.3 14.8 11.5 24.2 15.9 12.3 10.6 10.8 16.9 22.9 10.0 16.7 15.6 19.9 22.8 14.1 19.2 20.0 9.9 9.7 9.2 15.1 28.0 17.5 13.9 10.8 14.2 28.9 14.5 22.3 16.2 19.4 11.3 22.8 8.7 16.3 14.1 10.4 16.6 17.2 28.6 11.2 11.1 17.4 12.7 20.3 38.2 17.7 12.2 17.7 23.7 14.9 18.5 15.8 7.1 15.3 20.2 27.0 11.8 13.6 14.2 11.6 25.0 12.7 14.0 14.5 12.4 3.9 5.9 5.0 3.9 4.7 5.4 5.8 5.5 5.1 4.1 6.1 4.6 3.7 5.5 5.0 4.5 5.4 3.9 6.6 7.1 9.7 9.2 6.8 7.4 6.7 7.1 6.8 6.6 7.1 7.7 12.9 19.2 19.1 14.0 13.8 51.2 35.1 61.9 25.6 11.9 23.0 13.2 21.9 28.6 53.0 22.0 8.4 36.9 13.4 27.6 25.4 28.8 125.8 24.5 16.1 15.1 2.4 9.9 18.8 28.5 43.1 14.5 12.8 28.8 8.2 15.6 13.6 49.3 20.9 16.8 16.8 14.5 36.7 14.6 25.9 28.7 9.6 14.8 16.0 25.3 19.3 12.6 18.6 14.1 19.4 23.2 13.2 11.7 9.9 43.9 28.8 33.2 38.7 15.0 6.6 11.6 18.8 66.8 26.4 21.8 50.3 68.7 15.0 11.4 18.1 112.0 KIAA1841 ENSG00000162929 KIAA1841 Q6NSI8 2 61065871-61138034 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 11.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Excitatory neurons: 91.2;Inhibitory neurons: 78.5;Oligodendrocytes: 63.8;Respiratory ciliated cells: 58.0;Rod photoreceptor cells: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051240 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli" "HPA051240: AB_2681401" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.18e-2)" "unprognostic (5.71e-8)" "unprognostic (1.13e-1)" "unprognostic (5.06e-3)" "unprognostic (7.53e-2)" "unprognostic (6.09e-2)" "unprognostic (8.92e-2)" "unprognostic (7.85e-6)" "unprognostic (8.54e-2)" "unprognostic (1.04e-2)" "unprognostic (3.51e-1)" "unprognostic (2.25e-1)" 2.4 1.6 3.2 1.8 3.7 1.1 1.8 4.1 6.2 4.2 1.2 3.2 2.6 1.8 2.2 1.6 3.4 1.3 2.5 3.4 3.3 1.2 1.0 3.6 1.5 5.2 3.2 1.0 1.6 1.3 3.3 1.6 5.7 4.2 3.7 11.2 1.4 1.3 1.8 3.9 2.8 2.4 2.2 1.4 2.5 3.7 5.2 2.5 1.8 2.2 1.6 1.5 1.8 6.1 5.1 10.9 12.5 5.3 6.5 7.7 4.3 10.1 2.2 4.8 4.4 3.4 3.2 2.1 2.6 7.5 9.8 6.3 8.2 3.3 6.7 10.0 3.0 2.2 6.9 8.8 3.5 2.5 2.0 3.7 4.9 8.8 3.1 5.3 7.1 3.0 2.1 1.7 13.5 0.4 2.1 1.7 3.9 5.9 2.5 6.7 10.5 0.5 5.4 10.6 7.5 4.7 11.8 2.6 3.4 9.1 1.8 2.7 9.4 7.8 3.1 6.5 6.8 1.0 3.1 3.0 5.6 1.8 5.5 0.4 0.5 1.8 0.4 0.7 0.4 0.5 0.4 0.2 0.5 0.1 0.0 0.3 1.3 0.5 1.0 0.3 1.5 0.2 3.2 3.7 4.1 6.2 3.4 3.3 5.2 3.2 5.7 2.2 5.2 6.1 12.9 6.4 5.8 26.1 1.5 2.5 3.2 4.4 1.8 14.5 3.5 2.8 7.0 2.8 11.6 3.7 56.3 1.1 4.5 7.5 0.0 3.8 4.0 22.4 8.3 8.0 7.7 5.5 91.2 6.2 2.7 8.0 14.8 4.5 1.3 18.6 7.1 0.9 5.8 8.4 78.5 5.3 4.1 5.9 5.3 2.6 3.7 5.2 3.6 22.5 9.1 5.1 7.2 19.1 63.8 9.2 8.4 1.9 2.0 4.0 4.7 0.8 58.0 45.4 0.0 4.4 7.5 10.5 20.7 4.8 3.3 0.4 4.0 0.9 4.7 2.7 C2orf74 LOC339804 ENSG00000237651 "Chromosome 2 open reading frame 74" A8MZ97 2 61145068-61164828 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 191.7;Early spermatids: 573.5;Proximal tubular cells: 142.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA026826 Approved Approved Centrosome NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Centrosome "HPA026826: AB_10671091" "unprognostic (1.20e-1)" "unprognostic (2.44e-1)" "unprognostic (2.03e-2)" "unprognostic (4.54e-2)" "unprognostic (8.10e-2)" "unprognostic (1.43e-1)" "unprognostic (2.97e-1)" "unprognostic (1.95e-1)" "unprognostic (1.01e-1)" "unprognostic (1.28e-3)" "unprognostic (3.57e-2)" "unprognostic (1.87e-1)" "unprognostic (1.54e-1)" "unprognostic (2.69e-2)" "unprognostic (6.65e-2)" "unprognostic (3.52e-1)" "unprognostic (6.22e-2)" 25.7 28.1 65.3 12.8 66.1 4.2 27.5 63.6 92.1 22.7 58.2 29.8 5.4 18.6 42.8 13.4 19.9 13.1 43.3 64.9 68.4 38.8 35.8 17.4 20.7 65.4 67.1 26.7 19.7 23.8 38.4 16.9 65.7 20.7 8.7 32.7 16.0 17.2 25.0 8.2 13.7 15.0 63.7 22.3 20.0 56.0 66.6 16.3 24.0 17.9 15.8 23.3 13.0 65.9 15.1 25.7 26.2 0.0 55.0 55.6 23.6 38.7 44.4 36.4 30.0 0.2 25.1 18.8 52.7 31.8 24.0 19.9 0.0 31.6 62.0 24.1 16.0 0.0 26.1 30.2 22.0 23.5 20.4 57.5 51.1 27.2 55.1 26.0 20.5 0.4 0.0 13.9 56.1 27.6 0.1 43.4 25.1 11.4 16.2 34.1 32.5 31.9 50.2 11.8 54.0 20.7 4.9 5.0 34.2 23.0 20.0 22.0 10.8 30.4 13.3 18.4 48.0 58.0 28.6 71.4 40.3 16.5 27.5 16.2 7.7 27.6 16.8 16.5 20.9 31.5 18.1 17.2 16.8 20.9 29.6 23.8 1.8 30.1 16.1 14.0 26.3 10.7 65.3 66.1 63.6 92.1 64.9 68.4 65.4 67.1 65.7 63.7 66.6 65.9 16.5 12.8 14.5 4.9 14.0 0.0 16.5 1.0 8.6 9.6 15.5 28.6 3.8 21.5 2.8 22.0 8.4 25.7 11.2 0.0 191.7 23.8 573.5 15.8 10.5 16.4 0.0 7.4 5.1 31.0 24.2 11.3 4.6 6.0 14.5 23.1 34.6 24.3 21.8 11.8 4.7 0.2 0.0 28.9 0.2 103.0 37.0 15.2 1.8 2.8 23.9 33.0 29.9 1.5 7.1 24.3 0.0 45.1 11.7 8.7 0.2 142.3 11.8 20.1 19.7 13.1 11.0 21.1 27.7 2.2 0.0 6.4 11.6 40.8 0.2 8.8 USP34 "KIAA0570, KIAA0729" ENSG00000115464 "Ubiquitin specific peptidase 34" Q70CQ2 2 61187463-61471087 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 310.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025815, HPA070764" Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA025815: AB_1858681, HPA070764: AB_2686308" "unprognostic (4.04e-2)" "unprognostic (8.21e-3)" "unprognostic (5.08e-2)" "unprognostic (3.14e-2)" "unprognostic (4.13e-2)" "unprognostic (1.43e-2)" "unprognostic (1.04e-1)" "unprognostic (2.66e-1)" "unprognostic (1.47e-1)" "unprognostic (2.90e-2)" "unprognostic (8.91e-2)" "unprognostic (4.62e-2)" "unprognostic (9.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.53e-1)" "unprognostic (6.34e-2)" "unprognostic (7.01e-2)" 32.2 36.0 49.9 21.7 53.9 37.7 35.6 57.7 58.3 36.1 59.9 47.0 14.8 38.4 54.4 35.8 33.3 21.1 33.7 49.7 53.5 43.3 34.8 36.4 44.1 52.1 51.8 43.4 32.4 35.1 45.0 17.4 52.3 38.6 26.8 77.5 27.2 32.4 53.9 41.4 40.8 27.9 50.3 45.8 36.3 45.1 54.5 47.8 32.2 36.8 45.1 36.9 32.8 56.8 43.6 29.9 38.9 40.3 71.8 48.1 32.4 26.3 37.1 23.0 21.7 43.0 16.3 102.2 27.0 56.9 24.3 23.4 30.9 34.4 42.6 36.7 24.4 61.6 29.5 69.6 60.2 46.1 37.8 52.9 43.6 41.9 62.1 55.7 49.0 28.8 42.7 32.2 51.5 40.6 30.6 66.6 26.3 43.9 23.9 32.4 46.5 27.7 67.9 52.2 31.9 34.0 40.5 30.1 48.3 49.4 16.0 33.2 43.6 36.1 48.2 21.5 34.7 37.0 19.7 103.6 33.8 42.5 31.7 2.1 1.2 1.6 3.8 1.1 3.5 2.6 2.6 2.9 1.0 3.1 2.9 3.9 1.8 3.1 2.8 3.2 2.5 1.4 49.9 53.9 57.7 58.3 49.7 53.5 52.1 51.8 52.3 50.3 54.5 56.8 64.5 64.1 68.3 193.6 82.8 61.1 54.2 40.3 46.7 139.7 54.0 46.6 46.0 48.6 54.6 33.1 250.2 33.5 87.3 46.0 9.8 41.4 133.5 59.9 66.9 59.3 48.6 53.2 256.6 33.6 23.8 53.0 73.9 70.6 32.3 78.0 31.8 38.9 21.6 107.7 240.4 37.8 59.0 45.4 48.6 138.0 56.8 56.0 40.9 212.7 55.2 60.0 87.6 232.2 310.0 49.9 41.1 67.0 69.9 79.9 38.3 23.4 44.1 178.1 26.3 78.2 63.9 95.8 115.9 53.1 61.4 53.4 70.5 74.7 35.6 69.9 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 28.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 100.1;Early spermatids: 183.2;Late spermatids: 293.1;Rod photoreceptor cells: 417.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032119 Approved NA Yes "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA032119: AB_10602806" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.23e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (1.56e-5)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (2.14e-2)" "unprognostic (4.35e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-2)" "unprognostic (3.93e-1)" "unprognostic (8.08e-3)" "unprognostic (7.04e-2)" 0.9 1.2 0.8 0.5 1.1 0.3 1.1 0.6 1.6 2.1 2.4 1.0 0.4 1.6 1.2 1.1 4.0 1.4 1.5 0.9 1.1 1.9 0.7 1.0 0.7 0.8 0.9 5.2 2.3 1.9 2.4 1.1 0.8 1.0 0.6 28.9 0.7 1.1 1.2 0.6 0.7 0.6 0.6 0.7 2.6 5.5 1.0 1.6 3.6 0.3 0.6 1.1 1.1 0.9 3.4 3.1 7.1 3.3 3.4 3.2 2.1 2.9 1.5 3.4 4.2 2.1 1.7 6.6 1.5 0.5 6.1 1.6 4.3 0.5 8.0 4.5 4.7 2.4 2.8 3.3 2.9 2.7 0.5 1.3 0.0 6.6 1.9 4.0 3.7 6.4 0.9 2.5 2.4 1.3 4.9 5.2 11.0 4.2 3.3 8.4 12.1 3.3 2.4 0.8 8.7 7.3 6.2 0.8 4.7 6.7 1.5 1.8 0.7 5.9 5.2 4.2 6.7 3.8 3.1 8.1 4.2 4.5 1.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.8 1.1 0.6 1.6 0.9 1.1 0.8 0.9 0.8 0.6 1.0 0.9 3.9 3.2 9.7 20.2 3.7 5.5 9.4 10.2 6.2 49.7 4.8 7.0 14.5 7.2 10.5 20.2 100.1 14.0 2.3 1.5 1.9 4.3 183.2 42.7 11.0 6.7 6.0 5.5 16.6 3.8 7.7 10.7 5.1 4.8 4.5 42.7 4.2 3.8 3.6 16.8 19.0 2.5 14.2 1.2 3.6 293.1 20.8 2.3 8.8 4.7 2.0 42.4 2.1 11.1 33.0 1.3 0.3 16.6 4.0 4.7 0.0 13.0 47.1 417.2 0.0 14.2 9.0 98.0 39.3 5.3 4.1 11.1 3.6 16.4 3.5 3.4 CCT4 Cctd ENSG00000115484 "Chaperonin containing TCP1 subunit 4" P50991 2 61868085-61888671 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029349 Supported Supported Nucleoplasm,Cytosol NA NA 1700000 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "HPA029349: AB_10600800" "prognostic unfavorable (2.03e-4)" "unprognostic (2.80e-2)" "unprognostic (6.46e-2)" "unprognostic (1.74e-3)" "unprognostic (5.03e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (9.37e-12)" "unprognostic (1.28e-3)" "unprognostic (2.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.88e-2)" "unprognostic (1.10e-1)" "unprognostic (2.10e-2)" "unprognostic (5.18e-2)" "unprognostic (2.00e-1)" "unprognostic (3.96e-1)" "unprognostic (2.14e-2)" 66.4 67.0 60.4 59.9 62.6 64.9 90.2 67.1 114.9 68.4 66.7 65.1 45.8 68.7 50.8 75.6 74.4 43.1 67.0 62.3 65.7 73.5 63.7 48.7 81.4 63.9 62.6 109.3 95.3 62.8 45.9 65.8 66.1 57.8 58.9 56.8 53.7 57.5 96.7 66.4 48.5 72.0 70.4 55.3 64.5 77.6 66.0 83.3 65.3 74.0 92.0 68.4 61.2 80.0 274.5 313.6 203.1 190.1 166.2 251.5 342.5 244.6 174.3 345.6 230.4 550.5 193.2 437.9 239.7 176.5 354.6 192.4 405.8 313.9 362.3 216.0 398.9 280.4 149.4 347.7 149.3 347.8 179.1 215.0 214.4 278.8 287.2 259.5 293.3 220.0 406.5 137.2 297.5 246.4 299.6 451.2 365.3 364.2 276.0 336.9 319.2 297.4 237.5 186.2 177.6 148.8 177.2 221.9 324.5 235.7 161.9 245.6 185.2 190.6 275.5 143.3 400.1 205.3 297.3 739.8 188.9 391.7 255.7 58.2 60.7 25.0 83.2 88.9 106.9 93.6 87.1 100.8 100.4 88.6 112.9 112.2 8.4 107.5 103.3 64.3 100.7 125.2 60.4 62.6 67.1 114.9 62.3 65.7 63.9 62.6 66.1 70.4 66.0 80.0 111.8 73.7 54.3 20.9 125.4 152.6 350.8 206.6 136.1 52.9 131.3 136.4 47.7 82.9 116.7 73.5 14.6 256.5 106.5 52.8 135.0 156.0 250.0 111.9 117.2 118.0 140.6 156.9 28.0 130.6 284.9 114.9 67.8 92.8 95.8 148.2 95.3 79.4 163.5 32.0 31.3 105.9 175.0 105.0 112.4 72.1 88.3 110.2 94.3 30.0 125.8 64.9 71.1 26.7 40.8 143.9 61.4 97.8 111.9 200.3 67.9 165.2 143.1 63.3 92.1 117.2 297.8 338.8 153.2 151.2 151.3 180.6 146.6 173.7 138.2 203.8 COMMD1 "C2orf5, MGC27155, MURR1" ENSG00000173163 "Copper metabolism domain containing 1" Q8N668 2 61888724-62147247 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034633, HPA049223" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA034633: AB_10601800, HPA049223: AB_2680680" "unprognostic (6.08e-2)" "unprognostic (2.34e-2)" "unprognostic (2.83e-1)" "unprognostic (1.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.22e-2)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (4.93e-1)" "unprognostic (3.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.07e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (1.27e-1)" "unprognostic (5.51e-2)" "unprognostic (2.77e-1)" 20.8 26.4 22.2 21.9 23.4 20.4 27.0 25.2 33.0 23.0 22.9 18.6 22.6 20.0 30.1 24.8 20.9 20.2 54.7 23.5 22.9 31.2 35.9 18.7 23.5 22.1 22.1 21.3 24.1 24.4 14.8 26.5 22.6 22.2 22.6 20.1 33.5 20.2 35.2 22.2 14.9 29.9 22.4 20.6 19.2 24.4 22.2 20.7 28.1 38.1 25.5 23.9 19.8 24.1 23.2 29.1 32.0 25.4 41.2 41.2 27.4 27.2 45.6 53.7 37.9 50.1 20.4 40.4 22.3 50.8 45.8 17.6 18.0 33.1 55.8 43.9 21.1 31.5 16.3 56.0 35.1 49.6 23.8 34.6 37.7 26.1 30.8 39.2 54.6 23.2 19.6 64.3 56.7 43.6 38.6 87.4 27.9 19.0 39.0 27.1 42.4 46.7 49.3 25.0 19.5 21.7 30.7 50.9 28.6 31.8 32.4 21.4 25.9 48.1 41.5 30.2 42.4 26.6 22.9 48.6 26.5 42.8 42.8 62.4 96.2 48.4 63.0 86.5 63.4 91.8 71.5 72.0 117.3 84.7 68.1 73.8 8.1 91.1 78.4 109.5 88.8 110.8 22.2 23.4 25.2 33.0 23.5 22.9 22.1 22.1 22.6 22.4 22.2 24.1 53.0 35.3 33.8 56.8 38.2 54.4 73.8 98.7 47.8 35.4 47.0 72.4 176.7 41.5 57.3 35.0 10.4 127.3 37.3 27.4 129.1 71.5 195.6 50.6 52.1 53.2 21.6 43.1 91.9 65.1 75.5 67.6 32.1 47.2 57.7 60.4 52.5 72.4 101.7 28.6 78.4 29.8 63.1 36.0 81.3 163.5 41.3 46.3 83.6 71.2 118.6 45.3 30.9 89.5 109.7 57.1 37.1 49.7 71.5 48.9 49.0 192.3 49.1 33.2 32.9 57.6 97.2 124.5 58.7 49.6 61.7 147.2 38.6 81.6 30.1 64.0 B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196115-62224731 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 115.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles NA NA 99000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" 17.3 20.8 6.6 13.3 13.6 72.7 26.1 5.9 9.8 25.9 9.0 19.4 27.7 24.6 6.2 25.1 12.7 27.4 19.0 6.8 8.6 33.4 21.8 34.2 24.1 6.9 8.3 5.9 39.7 7.6 13.2 30.6 9.7 10.8 24.3 5.2 15.5 8.2 3.2 11.0 14.4 24.1 6.1 14.9 18.2 7.6 8.5 25.5 19.5 9.0 18.3 20.1 12.8 6.7 20.7 14.0 20.9 9.3 22.5 10.0 60.0 19.8 21.8 15.4 20.5 29.2 32.5 22.3 17.8 18.5 21.6 19.4 13.3 16.6 26.5 46.8 10.8 55.1 6.4 17.2 16.8 33.2 23.8 12.3 30.7 29.6 10.5 11.0 23.4 15.3 30.4 13.7 18.9 15.7 63.7 49.6 20.0 37.4 5.8 115.0 14.4 12.3 29.2 20.1 20.1 14.9 14.1 29.9 23.5 33.4 8.6 38.7 26.7 18.6 16.4 31.7 19.9 38.2 14.4 96.2 14.6 56.5 18.4 14.9 9.0 56.2 20.0 8.6 28.0 14.8 14.7 34.6 10.6 16.6 17.3 26.0 21.3 41.0 11.7 13.3 26.2 17.6 6.6 13.6 5.9 9.8 6.8 8.6 6.9 8.3 9.7 6.1 8.5 6.7 40.3 64.1 9.8 2.0 31.4 71.5 30.9 20.8 92.2 15.6 40.0 20.7 9.2 18.6 21.9 18.4 0.0 40.9 43.8 42.7 23.5 24.0 0.1 51.1 30.3 31.8 9.5 61.6 11.2 57.2 38.3 19.5 36.7 97.3 3.8 9.7 37.5 21.3 60.4 0.0 3.4 22.7 87.5 20.5 58.5 0.7 2.5 34.4 35.6 14.0 19.7 8.6 18.6 2.5 7.2 36.3 24.8 2.2 25.8 25.5 14.2 19.0 19.1 2.1 65.7 8.1 68.2 0.3 1.6 77.4 64.8 65.3 45.9 10.6 13.9 41.1 TMEM17 FLJ34583 ENSG00000186889 "Transmembrane protein 17" Q86X19 2 62500218-62511894 "Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 25.4;Spermatocytes: 39.2;Spermatogonia: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.9" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018100 Uncertain Approved "Actin filaments" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 17: WM-115 - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Actin filaments" "HPA018100: AB_2240686" "unprognostic (8.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (5.02e-3)" "unprognostic (3.78e-1)" "unprognostic (1.87e-4)" "unprognostic (1.21e-1)" "unprognostic (1.47e-1)" "unprognostic (3.44e-2)" "unprognostic (2.26e-1)" "unprognostic (2.36e-1)" "unprognostic (7.68e-3)" "unprognostic (1.11e-2)" "unprognostic (3.06e-2)" "unprognostic (3.62e-1)" "unprognostic (1.49e-6)" 2.4 5.0 4.1 0.5 4.3 0.8 2.4 2.6 4.2 1.8 4.8 1.4 1.0 2.3 1.6 2.6 4.3 2.9 2.2 4.4 9.5 4.3 2.3 1.8 1.0 4.5 5.5 3.1 3.2 6.1 4.3 1.7 5.5 2.5 0.9 4.0 2.2 2.0 1.8 2.4 0.8 1.6 3.5 0.8 1.3 4.8 8.5 1.4 4.6 1.8 0.9 1.5 1.3 3.4 3.3 4.6 4.7 1.8 2.4 3.1 3.0 2.5 2.3 2.0 2.1 0.3 6.1 0.0 3.2 3.3 6.7 3.2 2.1 1.4 1.5 3.2 1.4 1.5 1.8 0.3 3.5 2.3 1.8 2.8 3.9 1.7 3.9 3.4 2.5 0.3 1.4 0.2 5.3 0.9 0.4 0.5 2.3 3.0 2.3 0.2 0.6 0.2 4.3 1.0 1.2 4.0 2.6 0.9 9.1 1.6 1.5 3.0 1.7 4.0 2.2 4.8 2.6 0.4 0.0 0.0 5.8 0.4 8.4 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.5 0.3 0.1 1.9 0.0 0.4 4.1 4.3 2.6 4.2 4.4 9.5 4.5 5.5 5.5 3.5 8.5 3.4 2.9 3.2 4.1 2.6 0.4 5.0 2.3 10.7 9.1 7.1 3.0 2.8 2.6 4.3 7.5 5.5 8.4 2.3 1.5 0.1 0.0 5.3 4.8 11.4 2.1 2.7 1.2 1.7 2.8 8.5 2.2 4.2 1.1 1.7 1.3 2.8 3.9 2.5 2.6 10.1 3.9 0.9 6.1 0.6 1.5 2.8 4.7 1.4 3.6 1.0 0.9 9.9 0.0 0.0 2.9 7.9 0.3 3.8 1.4 1.0 0.4 2.5 25.4 4.8 6.6 2.4 1.8 39.2 21.7 5.5 2.8 0.4 0.3 5.4 1.1 1.5 EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 203.4;Early spermatids: 220.3;Excitatory neurons: 262.3;Inhibitory neurons: 245.4;Late spermatids: 495.6;Oligodendrocyte precursor cells: 226.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" 30.0 17.2 15.1 10.7 16.3 6.4 17.4 27.7 19.3 29.0 11.7 41.9 9.7 31.1 7.9 29.5 21.3 20.4 11.7 20.0 16.5 17.1 53.9 11.6 8.8 13.3 22.1 48.0 15.9 15.2 12.2 11.9 14.1 16.0 14.2 20.9 15.7 18.6 8.0 13.0 14.9 30.0 10.9 8.1 17.5 37.4 22.6 13.4 14.4 13.1 10.2 18.1 21.6 16.2 49.7 66.9 26.8 16.4 46.1 89.0 27.2 43.6 42.4 31.6 25.9 80.4 36.2 34.2 15.4 79.8 47.5 29.1 35.1 30.5 51.9 36.3 16.5 29.7 22.9 95.2 31.5 17.5 21.5 40.9 54.1 31.6 61.9 31.3 20.5 26.7 20.6 19.1 51.1 19.4 20.0 10.9 26.3 40.8 26.2 17.8 33.8 14.9 20.8 16.1 29.6 23.6 35.1 25.9 43.0 28.5 12.6 17.0 15.2 33.3 34.4 55.8 23.0 21.5 16.2 32.7 33.3 26.3 69.4 0.2 2.2 2.5 4.1 2.4 4.0 6.3 4.2 3.9 3.7 4.9 4.2 3.6 0.8 3.4 1.3 2.4 2.5 2.2 15.1 16.3 27.7 19.3 20.0 16.5 13.3 22.1 14.1 10.9 22.6 16.2 29.0 38.5 18.8 203.4 10.4 15.6 12.0 27.1 43.3 39.7 10.5 12.8 15.2 22.8 20.7 14.7 4.2 10.9 9.9 5.3 15.6 22.1 220.3 10.3 45.4 19.9 16.2 8.8 262.3 40.5 30.1 36.6 9.2 12.1 2.5 15.2 30.0 59.6 5.0 18.5 245.4 5.4 6.1 8.6 11.4 495.6 58.4 7.6 10.6 119.0 6.5 20.1 13.4 226.7 98.7 41.7 5.0 40.3 9.6 13.9 11.4 15.1 14.5 17.8 6.6 33.1 19.4 53.7 31.1 55.4 14.2 2.9 12.7 18.2 8.1 13.1 OTX1 ENSG00000115507 "Orthodenticle homeobox 1" P32242 2 63050057-63057836 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "salivary gland: 18.0;skin 1: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 9.8;Basal respiratory cells: 6.3;Club cells: 4.1;Ionocytes: 6.1;Respiratory ciliated cells: 6.8;Suprabasal keratinocytes: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 95 "neutrophil: 9.4" "Lineage enriched" "Detected in single" 95 "granulocytes: 9.4" "Cell line enriched" "Detected in many" 9 "THP-1: 54.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052122 Uncertain Approved Nucleoplasm NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "HPA052122: AB_2681736" "unprognostic (2.25e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.36e-3)" "unprognostic (2.32e-1)" "unprognostic (1.67e-2)" "unprognostic (6.92e-3)" "unprognostic (3.66e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (2.26e-3)" "unprognostic (1.71e-1)" "unprognostic (0.00e+0)" "unprognostic (4.64e-2)" "unprognostic (2.31e-1)" "unprognostic (3.80e-4)" "unprognostic (3.67e-3)" 0.1 0.0 2.1 0.0 1.7 0.0 0.2 0.1 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.1 0.0 0.2 2.5 0.0 0.2 0.0 0.0 0.0 0.7 0.7 0.0 0.0 18.0 0.0 0.0 8.4 0.0 0.0 0.0 0.1 0.2 0.3 2.8 0.0 0.0 0.0 0.5 0.0 0.1 1.8 2.3 1.3 4.2 2.5 0.0 0.1 5.9 0.0 0.3 0.3 0.4 4.4 2.2 0.1 0.8 0.0 1.1 3.0 2.7 1.9 0.5 1.1 2.5 2.7 2.2 5.0 0.0 1.9 2.0 0.0 0.7 0.0 0.7 0.8 0.0 2.6 2.4 0.0 0.2 2.1 2.6 4.6 0.0 2.2 1.6 2.3 3.6 0.7 1.2 0.8 0.4 0.5 1.8 0.2 1.5 0.0 1.0 54.1 0.1 0.9 1.7 0.0 0.9 1.5 1.1 4.0 0.3 2.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.5 1.9 1.4 0.2 2.5 0.7 0.0 2.8 1.8 0.2 0.0 0.0 9.8 0.1 1.7 0.0 6.3 0.6 0.0 0.8 1.0 0.8 0.0 4.1 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.2 0.6 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.1 0.0 0.0 0.3 0.0 0.0 6.8 0.0 0.0 0.7 0.3 0.3 0.5 1.1 2.6 0.1 0.0 0.1 0.2 0.1 WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Alveolar cells type 2: 128.0;Astrocytes: 124.7;Excitatory neurons: 261.4;Inhibitory neurons: 240.9;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 296.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Cell Junctions" Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 6: Brain - Smell perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA044144: AB_10969458" "unprognostic (3.36e-1)" "unprognostic (3.22e-2)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-3)" "unprognostic (7.22e-2)" "unprognostic (6.48e-2)" "unprognostic (1.93e-1)" "unprognostic (4.87e-2)" "unprognostic (2.34e-3)" "unprognostic (6.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.25e-3)" "unprognostic (2.00e-1)" 4.7 3.5 11.3 2.5 11.7 8.2 3.2 17.7 15.7 2.5 6.5 1.6 1.8 3.9 4.0 2.0 4.2 2.8 4.9 10.4 6.9 3.6 2.4 2.5 3.3 6.4 5.4 4.6 1.5 2.9 1.9 2.6 8.4 2.6 1.8 12.2 2.2 2.1 5.3 3.4 1.7 3.0 3.2 3.3 3.3 5.1 6.3 3.6 3.5 2.9 2.7 1.8 1.1 18.6 5.2 4.6 3.3 4.0 3.7 4.6 3.0 4.3 2.2 2.8 2.3 3.3 2.6 5.8 3.5 2.9 3.3 3.4 2.3 2.8 3.3 5.7 3.8 6.1 3.5 2.8 2.5 5.0 4.1 2.3 1.9 2.9 1.9 3.7 2.9 6.7 2.3 5.7 2.9 5.3 5.8 5.1 3.9 2.7 1.7 6.2 4.3 5.0 1.9 2.5 5.2 5.2 3.7 4.4 5.3 4.7 3.8 3.9 4.7 4.6 7.2 4.0 3.6 5.3 3.6 10.3 5.2 5.3 5.3 6.6 2.8 1.5 1.9 1.5 3.7 1.8 1.7 2.6 2.3 3.1 2.3 3.6 1.9 3.8 1.3 2.7 1.5 1.1 11.3 11.7 17.7 15.7 10.4 6.9 6.4 5.4 8.4 3.2 6.3 18.6 6.0 169.9 128.0 124.7 8.0 4.1 3.2 4.3 2.8 16.1 4.4 3.2 10.1 7.2 59.6 1.8 22.9 2.5 5.5 0.8 1.9 2.6 46.7 17.9 6.2 14.4 0.0 7.8 261.4 2.2 2.6 13.5 6.6 3.7 65.0 7.4 5.0 1.8 4.0 11.8 240.9 1.3 4.1 3.0 4.4 17.5 4.4 8.4 5.4 103.0 3.8 7.5 6.2 136.2 296.3 1.8 1.6 3.8 5.1 1.5 0.5 4.5 98.8 27.4 0.0 8.6 5.7 16.1 9.5 2.3 3.4 1.9 9.4 4.0 1.1 1.7 MDH1 ENSG00000014641 "Malate dehydrogenase 1" P40925 2 63588609-63607197 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1349.1;tongue: 1843.8" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1926.9;Proximal tubular cells: 1428.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027296, CAB047333, HPA054276" Uncertain Supported Centrosome,Cytosol NA NA 49000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Centrosome, Cytosol" "CAB047333: , HPA027296: AB_10611118, HPA054276: AB_2682434" "unprognostic (1.01e-1)" "unprognostic (6.52e-3)" "unprognostic (1.61e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (1.83e-1)" "unprognostic (8.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.79e-2)" "unprognostic (9.52e-2)" "unprognostic (2.05e-1)" "unprognostic (3.26e-1)" "unprognostic (8.80e-2)" "prognostic favorable (9.95e-4)" "unprognostic (6.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.97e-2)" "unprognostic (3.05e-1)" 274.6 213.6 235.9 86.7 249.7 79.1 137.9 245.9 353.6 89.6 230.2 167.7 154.7 82.0 161.3 125.3 114.5 87.2 1349.1 253.2 261.5 371.6 266.3 89.8 131.9 248.5 218.3 80.4 69.9 411.8 107.2 92.5 253.3 125.5 190.9 240.7 122.0 142.0 792.5 87.7 133.1 171.5 215.7 71.6 192.6 70.5 259.1 170.4 125.5 1843.8 165.4 131.5 62.8 237.7 268.2 219.5 257.8 173.2 369.6 280.9 282.3 215.1 295.9 300.6 304.1 252.5 215.4 355.2 112.8 264.1 358.8 214.3 303.0 355.0 425.5 207.6 253.1 337.0 173.2 376.8 202.1 384.1 223.9 277.7 241.3 271.5 152.7 236.2 235.3 308.1 183.7 217.3 395.1 157.8 300.6 317.5 158.0 376.3 266.5 235.2 349.7 310.5 460.9 251.0 249.9 153.6 182.5 257.7 384.1 205.6 191.9 341.9 149.6 220.3 211.9 187.1 252.9 264.6 264.8 407.6 266.2 312.2 184.1 271.3 186.3 200.2 202.7 267.8 218.8 258.5 236.6 224.6 241.0 258.5 230.3 221.6 28.1 214.6 253.4 184.3 320.9 321.2 235.9 249.7 245.9 353.6 253.2 261.5 248.5 218.3 253.3 215.7 259.1 237.7 44.4 60.9 54.3 54.9 78.7 81.6 109.4 562.9 50.7 165.4 81.0 86.7 1926.9 95.8 227.2 134.3 70.9 248.7 78.4 128.4 630.0 186.2 12.4 116.1 72.6 61.0 62.8 62.9 120.2 108.1 257.0 134.7 112.7 68.8 80.5 95.0 36.0 153.2 397.0 122.8 130.0 115.9 380.5 85.2 65.8 15.1 100.0 98.4 177.9 43.1 155.0 136.3 73.2 51.3 58.8 91.3 99.8 109.1 82.1 48.8 177.4 1428.3 224.5 164.1 59.2 68.3 167.8 58.0 65.6 82.7 84.0 149.5 84.3 137.4 167.8 102.6 UGP2 "SVUGP2, UGP1, UGPP1" ENSG00000169764 "UDP-glucose pyrophosphorylase 2" Q16851 2 63840952-63891562 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 858.6;tongue: 756.1" "Cell type enhanced" "Detected in all" "Distal enterocytes: 849.9;Hepatocytes: 559.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 417.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034696, HPA034697, HPA064836" Enhanced Approved Nucleoplasm,Centrosome,Mitochondria NA NA 13000000 "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "Centrosome, Mitochondria" Nucleoplasm "HPA034696: AB_10670171, HPA034697: AB_2674287, HPA064836: AB_2685365" "unprognostic (1.00e-2)" "unprognostic (6.93e-2)" "unprognostic (5.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "prognostic favorable (2.50e-5)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (1.84e-1)" "unprognostic (1.57e-2)" "unprognostic (8.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-2)" "unprognostic (3.93e-2)" "unprognostic (3.81e-1)" "unprognostic (8.44e-2)" 267.3 72.0 79.8 65.8 89.3 40.1 119.7 72.7 109.8 65.9 78.8 177.9 66.0 75.2 50.6 97.5 68.9 60.7 232.5 87.9 81.4 105.4 858.6 65.4 65.7 77.7 77.0 47.0 74.4 113.3 49.8 137.8 77.6 57.4 159.3 36.8 92.9 66.2 498.0 59.1 67.6 78.5 73.2 50.8 69.5 38.3 83.3 106.2 64.5 756.1 73.7 88.4 63.7 91.8 122.3 77.6 63.1 42.0 176.1 222.4 220.6 129.1 116.1 82.7 89.4 170.0 104.5 149.5 48.3 165.6 79.9 57.4 73.4 102.6 137.0 99.2 35.7 86.5 50.4 117.9 87.0 79.1 73.9 148.1 175.8 76.1 80.3 108.4 119.4 38.9 48.2 58.1 327.8 56.7 104.6 75.2 122.9 207.7 50.1 80.4 117.9 84.5 147.4 77.7 36.5 29.6 103.3 149.8 64.3 162.6 51.7 59.2 144.3 84.4 125.9 113.8 90.5 101.3 51.4 174.9 99.2 122.7 225.7 417.1 33.0 53.1 48.0 40.7 51.8 33.0 53.6 50.1 27.9 31.8 57.6 53.6 45.4 70.0 39.5 29.7 127.2 62.0 79.8 89.3 72.7 109.8 87.9 81.4 77.7 77.0 77.6 73.2 83.3 91.8 73.4 28.9 54.0 107.4 65.3 75.8 87.8 245.9 34.7 49.6 360.6 87.1 264.3 104.4 171.6 47.8 64.6 414.3 81.1 849.9 242.6 140.6 91.5 53.0 106.3 69.8 44.5 56.0 86.1 103.6 445.5 159.3 79.0 49.5 67.8 42.4 63.5 559.4 120.9 87.5 78.4 179.8 144.5 102.4 90.2 86.1 79.2 89.1 96.0 62.8 139.7 58.8 154.5 37.2 79.3 91.6 313.9 77.5 60.7 81.2 176.2 284.4 139.3 57.3 72.3 50.5 129.2 84.9 54.9 50.9 57.8 472.8 143.1 90.6 189.5 109.1 VPS54 "HCC8, PPP1R164" ENSG00000143952 "VPS54 subunit of GARP complex" Q9P1Q0 2 63892146-64019428 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 81.8;Microglial cells: 76.8;Oligodendrocyte precursor cells: 105.6;Oligodendrocytes: 108.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055894, HPA067981, HPA070582" Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" Nucleoplasm "HPA055894: AB_2682961, HPA067981: AB_2685938, HPA070582: AB_2686282" "unprognostic (1.35e-1)" "unprognostic (3.37e-2)" "unprognostic (6.47e-2)" "unprognostic (2.46e-1)" "unprognostic (3.37e-1)" "unprognostic (9.47e-3)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.16e-1)" "unprognostic (4.62e-2)" "unprognostic (1.82e-1)" "prognostic favorable (2.03e-4)" "unprognostic (3.20e-1)" "unprognostic (8.38e-2)" "unprognostic (3.02e-2)" "unprognostic (1.36e-1)" "unprognostic (1.57e-1)" "unprognostic (4.91e-2)" 11.7 11.5 8.1 10.6 9.7 15.0 14.5 13.5 9.6 13.5 10.9 11.6 13.0 14.4 12.3 10.8 12.4 10.4 8.4 7.8 8.5 16.0 14.4 13.1 11.1 8.8 8.7 14.6 17.0 28.3 13.0 13.5 8.9 17.4 13.4 17.3 36.8 12.8 9.3 10.9 12.2 12.8 8.5 12.9 14.4 13.4 8.5 13.2 17.7 9.9 11.2 10.9 9.8 11.0 23.3 11.9 22.5 17.4 15.7 17.1 16.6 14.3 21.4 15.0 14.9 22.0 14.9 15.8 10.5 20.1 22.3 10.7 22.1 12.9 27.1 23.0 15.9 14.7 10.0 38.9 15.0 10.3 6.2 16.3 19.8 10.5 22.7 18.0 23.0 11.3 16.6 13.4 19.4 10.1 10.9 11.5 13.8 22.9 9.1 10.8 21.8 9.0 17.1 13.1 13.1 19.6 12.8 16.3 17.8 17.3 11.9 20.6 16.8 19.3 15.3 11.8 23.9 30.8 8.7 20.4 14.3 20.5 16.4 1.0 0.7 0.3 0.5 0.6 0.5 0.6 0.4 0.5 0.4 0.7 0.6 0.5 0.6 0.7 0.5 0.6 0.9 0.2 8.1 9.7 13.5 9.6 7.8 8.5 8.8 8.7 8.9 8.5 8.5 11.0 16.6 16.0 22.3 62.7 5.2 11.1 8.7 6.4 3.4 20.9 11.8 9.8 14.3 15.7 14.2 1.8 12.5 6.5 6.4 11.1 1.9 6.8 53.9 9.3 16.6 13.4 13.2 2.1 71.6 13.2 6.8 11.8 15.8 11.0 2.5 15.2 10.8 15.4 8.1 23.5 81.8 17.4 2.0 9.8 9.3 37.4 18.6 12.2 5.4 76.8 9.6 9.4 3.1 105.6 108.9 11.3 12.8 12.4 7.7 17.3 11.6 9.9 10.6 16.2 19.7 13.4 12.8 14.9 8.3 9.4 10.4 5.5 7.5 15.9 12.9 13.8 PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 228.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.1;Plasma cells: 318.8;Squamous epithelial cells: 208.0;Suprabasal keratinocytes: 217.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 76.9" "Group enriched" "Detected in all" 4 "granulocytes: 76.9;monocytes: 23.2" "Cell line enhanced" "Detected in many" "CACO-2: 58.8;U-698: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053182 Approved Approved "Nucleoplasm,Nucleoli,Intermediate filaments" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nucleoli, Intermediate filaments" "HPA053182: AB_2682072" "unprognostic (3.33e-2)" "unprognostic (3.43e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (3.12e-3)" "unprognostic (6.73e-3)" "unprognostic (8.01e-3)" "unprognostic (4.16e-2)" "unprognostic (3.52e-3)" "unprognostic (5.99e-3)" "unprognostic (3.33e-1)" "prognostic unfavorable (5.67e-6)" "unprognostic (6.72e-2)" "unprognostic (6.22e-2)" "unprognostic (8.88e-2)" "unprognostic (1.03e-1)" 27.6 7.9 10.2 28.1 14.4 228.5 25.7 11.9 13.5 17.9 9.2 18.6 17.6 17.3 8.6 42.9 12.7 26.1 11.8 13.8 11.2 10.6 13.5 31.0 24.7 12.2 11.2 5.5 9.3 37.9 15.8 15.6 12.2 8.9 20.1 5.1 18.9 7.7 7.1 29.7 23.2 13.9 12.6 21.8 18.1 10.7 10.9 28.3 9.7 10.0 29.0 22.4 23.7 15.6 3.6 2.8 36.5 24.6 4.2 3.2 8.3 4.8 5.4 4.3 6.8 58.8 4.1 48.3 11.3 1.7 1.6 5.8 11.1 10.5 8.6 12.2 8.9 4.4 1.7 9.5 12.4 4.8 8.3 4.2 8.1 6.4 21.6 4.5 24.3 18.2 2.7 11.7 3.7 0.3 10.6 6.9 23.8 11.1 1.7 13.2 12.6 28.1 17.7 10.8 16.7 23.3 3.6 5.5 12.9 11.3 3.0 3.3 17.5 4.0 5.7 4.0 7.1 27.0 2.8 146.7 2.1 4.3 10.9 15.0 15.6 15.0 0.9 14.1 1.7 8.5 4.8 1.9 5.4 6.6 5.6 2.5 76.9 3.0 23.2 0.5 11.6 6.6 10.2 14.4 11.9 13.5 13.8 11.2 12.2 11.2 12.2 12.6 10.9 15.6 94.5 28.9 49.2 4.6 84.4 224.1 74.6 48.2 105.9 1.7 60.9 50.3 5.7 15.7 52.0 5.5 0.0 1.7 16.9 57.9 1.9 5.3 10.6 34.6 26.4 52.1 25.7 3.4 23.4 26.7 8.6 24.5 75.4 58.7 15.2 6.3 37.5 7.5 22.8 3.3 19.1 23.4 30.5 67.6 103.7 11.2 1.5 107.0 112.1 119.9 30.6 5.5 3.1 82.9 67.9 20.9 45.9 1.9 318.8 44.7 32.7 9.6 43.6 2.0 0.0 10.1 51.9 8.4 9.6 208.0 217.5 4.0 49.4 3.2 32.4 145.8 LGALSL "GRP, HSPC159" ENSG00000119862 "Galectin like" Q3ZCW2 2 64453969-64461381 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 90.6;skin 1: 93.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 95.6;Rod photoreceptor cells: 152.8;Suprabasal keratinocytes: 137.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.5;neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 50.2;CACO-2: 35.6;HAP1: 72.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046079 Approved Approved Nucleoplasm NA NA 4100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA046079: AB_10967075" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "unprognostic (7.18e-2)" "unprognostic (3.77e-2)" "unprognostic (3.12e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (1.25e-2)" "unprognostic (8.43e-2)" "unprognostic (3.57e-3)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (4.34e-2)" "unprognostic (6.57e-2)" "unprognostic (6.20e-2)" "unprognostic (9.19e-2)" "unprognostic (2.77e-2)" 9.3 16.9 7.1 4.1 8.3 8.1 17.2 9.5 8.7 8.8 8.6 12.6 10.1 7.2 8.9 24.6 5.3 6.3 13.5 7.4 8.6 9.2 9.6 15.9 2.1 5.7 5.4 6.4 6.3 19.2 7.5 10.6 5.7 15.5 11.8 90.6 9.3 7.1 60.1 93.6 10.9 7.3 5.4 6.0 8.8 4.3 5.8 2.9 5.3 18.2 15.8 4.4 10.0 6.6 11.6 7.5 20.7 50.2 0.7 0.2 6.2 2.9 8.1 6.3 6.0 35.6 2.4 0.0 4.7 1.6 12.2 14.3 72.8 13.7 5.0 13.8 19.1 0.2 4.0 17.8 6.2 3.4 4.4 3.1 8.6 2.6 9.7 5.6 3.9 7.7 0.1 3.5 0.2 9.3 4.9 0.6 16.8 7.1 8.8 5.3 12.0 3.5 7.5 8.5 3.5 13.1 10.5 7.2 6.2 12.7 5.1 0.5 1.7 4.0 12.4 2.5 6.2 14.7 7.1 10.0 0.0 2.1 5.4 0.0 0.1 1.5 0.0 0.0 0.7 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.4 7.1 8.3 9.5 8.7 7.4 8.6 5.7 5.4 5.7 5.4 5.8 6.6 28.9 22.4 66.2 2.3 6.0 67.6 25.5 9.7 29.0 31.9 39.0 20.8 16.5 10.0 6.3 11.0 33.3 1.4 1.6 45.2 15.6 6.2 11.8 10.9 8.1 18.2 9.1 0.8 6.6 13.3 2.7 14.8 23.4 23.0 1.3 4.1 17.9 11.9 1.0 13.5 6.0 38.6 6.1 6.6 14.4 6.3 8.1 26.2 10.6 1.9 2.4 95.6 2.1 5.0 2.4 19.9 22.6 4.5 29.8 24.1 31.0 14.3 1.6 152.8 19.7 15.1 45.9 8.1 5.1 51.9 137.0 1.5 2.7 2.8 24.3 36.2 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 SERTAD2 "KIAA0127, Sei-2, TRIP-Br2" ENSG00000179833 "SERTA domain containing 2" Q14140 2 64631621-64751005 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 85.7" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 177.6;Basal squamous epithelial cells: 153.1;Suprabasal keratinocytes: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019021, HPA020904" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA019021: AB_1856740, HPA020904: AB_1856741" "unprognostic (1.40e-2)" "unprognostic (7.41e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.15e-2)" "unprognostic (8.15e-2)" "unprognostic (3.39e-3)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (5.95e-3)" "unprognostic (1.98e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.21e-3)" "unprognostic (6.78e-2)" "unprognostic (4.98e-2)" "unprognostic (3.84e-1)" 14.1 6.7 4.3 13.8 5.8 85.7 9.4 5.3 5.5 12.7 3.8 8.5 6.2 8.6 7.9 22.8 6.9 9.4 10.3 5.0 4.5 7.5 14.6 9.7 19.2 6.3 5.9 13.5 6.6 10.7 3.6 12.6 5.8 9.3 8.7 15.6 11.7 8.5 8.6 18.8 9.0 8.1 5.4 19.3 9.2 7.2 5.3 35.3 8.1 9.6 27.3 15.9 16.8 7.1 30.9 9.0 16.5 16.6 13.9 35.2 18.9 24.2 23.2 14.1 13.2 23.1 23.0 26.0 13.0 39.8 19.6 12.0 10.9 14.8 29.6 2.5 16.4 17.2 8.8 16.8 3.1 15.3 8.4 24.0 19.1 32.2 20.9 21.1 8.6 12.7 10.9 14.1 33.2 7.4 16.5 16.7 9.0 16.9 23.6 14.3 28.2 10.2 19.1 28.0 19.1 7.5 17.1 11.9 31.5 15.3 7.9 12.1 26.1 75.7 39.1 44.8 19.9 24.0 9.8 29.6 28.0 27.7 30.3 1.3 1.6 2.3 0.9 1.5 0.5 2.5 0.9 1.0 1.5 2.5 2.2 1.6 2.0 1.5 1.8 4.9 0.5 0.9 4.3 5.8 5.3 5.5 5.0 4.5 6.3 5.9 5.8 5.4 5.3 7.1 25.6 6.4 23.6 22.9 40.8 177.6 40.9 22.5 153.1 24.8 28.7 28.6 26.4 32.9 25.9 9.2 18.8 38.6 33.0 31.6 1.9 12.8 51.2 57.8 18.5 35.4 11.3 26.5 27.3 10.0 42.8 35.1 17.3 97.7 8.8 4.8 25.4 24.1 23.6 10.1 19.8 17.1 18.3 39.3 84.7 35.4 17.1 43.6 39.2 38.4 27.4 20.0 14.4 19.6 35.5 20.7 45.4 10.5 28.1 43.9 11.6 9.5 24.9 24.3 13.1 26.8 31.0 10.8 6.7 135.4 148.3 60.1 25.5 3.7 13.3 71.5 SLC1A4 "ASCT1, SATT" ENSG00000115902 "Solute carrier family 1 member 4" P43007 2 64988477-65023865 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 59.9" "Cell type enhanced" "Detected in many" "Astrocytes: 69.9;Granulosa cells: 49.2;Melanocytes: 85.4;Plasma cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "SK-MEL-30: 294.5;U-266/70: 132.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034963, HPA034964" Approved Enhanced Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 65: Plasmacytoid DCs - Unknown function" Centrosome "HPA034963: AB_2797223, HPA034964: AB_2674386" "unprognostic (7.61e-2)" "prognostic favorable (3.59e-4)" "unprognostic (2.49e-1)" "unprognostic (3.19e-3)" "unprognostic (1.26e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.23e-5)" "unprognostic (1.26e-2)" "unprognostic (2.10e-1)" "unprognostic (3.16e-2)" "unprognostic (2.28e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.87e-4)" "unprognostic (6.37e-3)" "unprognostic (4.14e-2)" "unprognostic (3.53e-2)" "unprognostic (1.98e-2)" 4.3 26.4 49.1 9.1 46.8 13.4 13.6 32.1 48.6 14.0 18.0 9.4 6.1 12.8 8.2 7.5 4.8 3.9 6.2 43.4 56.6 1.9 9.0 4.9 10.7 37.2 43.1 13.2 29.6 5.5 13.7 6.6 52.1 9.6 8.4 19.3 7.5 7.1 40.1 18.6 5.6 12.3 29.5 7.5 8.1 11.7 59.9 20.5 5.7 17.0 19.0 4.8 6.2 30.3 15.3 11.6 6.6 34.9 14.7 9.5 9.4 28.5 14.0 11.7 19.8 3.2 2.2 49.7 6.5 44.8 14.7 43.2 13.7 3.6 12.0 20.1 5.4 26.0 13.1 30.9 31.0 43.8 23.1 4.4 73.8 15.8 24.2 3.9 7.3 49.1 20.7 122.0 8.4 13.5 37.7 29.1 4.7 20.1 13.9 13.5 1.9 125.5 4.9 7.7 29.3 14.1 17.9 16.1 294.5 3.0 19.3 47.8 1.6 16.0 19.0 31.2 17.5 132.8 71.2 118.8 23.6 86.5 86.2 0.0 2.1 1.8 0.9 4.8 1.2 0.9 0.9 1.5 3.9 0.3 0.0 0.8 0.0 5.1 9.4 7.2 3.5 1.4 49.1 46.8 32.1 48.6 43.4 56.6 37.2 43.1 52.1 29.5 59.9 30.3 3.6 0.0 2.7 69.9 13.6 20.0 2.1 6.7 46.1 6.3 21.0 7.1 5.5 1.5 1.7 1.8 33.3 2.4 20.2 2.9 0.0 2.0 32.4 5.4 8.2 5.3 8.4 6.1 20.6 9.3 1.3 4.0 5.1 5.6 7.0 49.2 7.5 13.1 17.7 6.7 25.5 9.0 6.1 6.8 11.8 47.5 11.1 11.1 85.4 8.4 5.1 14.6 2.1 5.0 3.9 7.1 0.8 29.7 65.7 2.6 0.4 1.5 5.4 17.7 0.0 5.1 7.3 2.0 0.9 5.9 6.1 2.5 10.9 0.4 5.8 1.0 CEP68 KIAA0582 ENSG00000011523 "Centrosomal protein 68" Q76N32 2 65056366-65087004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 72.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040493, HPA040620" Enhanced Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Centriolar satellite" "HPA040493: AB_10673411, HPA040620: AB_10794144" "unprognostic (7.99e-2)" "unprognostic (6.15e-2)" "unprognostic (5.09e-2)" "unprognostic (4.90e-3)" "unprognostic (1.31e-2)" "unprognostic (1.75e-2)" "unprognostic (4.84e-3)" "unprognostic (8.25e-3)" "unprognostic (9.94e-2)" "unprognostic (5.09e-2)" "unprognostic (9.22e-2)" "unprognostic (1.77e-1)" "prognostic favorable (3.93e-4)" "unprognostic (2.25e-1)" "unprognostic (2.50e-1)" "unprognostic (8.45e-2)" "unprognostic (1.71e-1)" 15.9 5.8 11.2 6.9 11.3 4.6 14.1 13.8 11.6 15.3 8.5 12.1 5.5 16.9 6.1 9.8 13.7 10.1 13.9 12.3 9.5 7.1 2.6 7.8 10.0 10.5 9.2 21.6 9.1 9.9 5.9 10.2 10.9 11.0 7.0 7.4 10.7 12.3 26.7 11.8 7.5 14.3 8.1 9.2 8.1 6.0 10.1 10.6 9.6 27.7 8.5 10.3 10.5 11.0 3.9 6.9 13.2 9.7 11.6 13.0 24.2 3.7 6.5 5.6 4.9 5.4 3.4 6.6 4.5 6.7 5.7 5.3 8.7 5.6 5.8 8.0 7.5 9.0 2.5 6.5 3.2 5.1 6.1 12.3 7.8 5.1 7.1 9.8 16.1 13.5 8.4 20.7 7.1 4.5 8.6 9.4 13.3 7.1 5.5 8.9 15.9 7.8 5.0 5.1 23.1 15.7 7.3 5.3 7.9 8.0 3.1 3.3 6.4 5.2 7.1 8.2 3.7 22.4 6.5 15.3 2.8 3.9 6.4 0.9 1.3 0.3 2.3 2.5 2.6 2.6 5.4 4.3 3.5 3.6 8.3 5.2 1.1 4.4 5.0 7.2 4.4 2.5 11.2 11.3 13.8 11.6 12.3 9.5 10.5 9.2 10.9 8.1 10.1 11.0 72.0 28.9 10.9 17.9 13.2 7.1 14.2 15.5 22.2 26.7 11.8 13.6 16.7 8.6 15.5 9.2 25.0 15.4 15.4 3.6 9.8 10.3 3.7 11.2 22.2 47.1 13.1 7.2 28.8 21.4 7.5 17.8 9.2 19.8 6.3 24.9 28.5 6.9 9.4 23.5 31.6 5.8 8.2 7.2 14.4 6.2 37.9 18.9 7.2 22.5 18.4 15.5 8.2 22.6 21.2 8.9 4.3 27.1 6.9 8.9 2.8 9.0 15.0 21.3 32.9 30.5 18.5 11.6 23.9 10.1 5.8 34.1 16.1 9.9 11.2 7.3 RAB1A "RAB1, YPT1" ENSG00000138069 "RAB1A, member RAS oncogene family" P62820 2 65070696-65130331 "Plasma proteins, Predicted intracellular proteins" "Autophagy, ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 911.4;Syncytiotrophoblasts: 703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005331, HPA056141" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 3000000 "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Cytosol" "CAB005331: AB_632290, HPA056141: AB_2683051" "unprognostic (4.78e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-3)" "unprognostic (2.08e-1)" "unprognostic (1.79e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (1.55e-3)" "unprognostic (2.61e-1)" "unprognostic (1.06e-1)" "unprognostic (1.35e-1)" "unprognostic (4.30e-3)" "unprognostic (2.79e-1)" "unprognostic (4.81e-2)" "unprognostic (2.77e-1)" "unprognostic (7.80e-2)" "unprognostic (1.83e-2)" "unprognostic (8.63e-2)" 142.5 142.9 84.2 90.6 86.8 232.4 119.1 85.2 105.2 122.6 103.7 128.1 133.6 109.7 179.9 155.0 103.5 100.1 127.3 89.0 91.9 194.1 194.9 141.9 70.5 86.0 88.4 94.4 133.9 113.1 117.2 148.3 91.3 96.6 126.8 89.4 131.8 93.8 100.3 101.3 127.6 117.4 87.7 88.6 135.9 86.2 90.4 59.0 129.6 80.4 91.1 119.2 120.5 91.3 211.3 150.7 186.2 110.5 445.5 261.2 287.5 299.9 212.3 134.8 142.8 270.1 137.5 85.8 167.9 311.2 221.4 130.6 173.7 277.6 214.1 96.3 100.6 108.3 119.2 403.8 281.9 115.4 93.7 232.0 279.6 176.9 158.5 213.3 271.2 67.7 157.2 96.6 271.1 190.6 67.3 138.6 148.6 329.1 134.6 68.3 177.3 137.3 266.1 236.0 133.9 118.5 139.2 230.6 282.4 218.7 143.3 106.9 253.4 172.5 214.6 183.2 171.8 147.6 95.3 205.6 230.2 173.9 170.4 96.8 84.6 78.7 41.9 86.3 46.7 42.6 45.4 45.8 76.0 29.3 43.2 45.1 102.1 56.4 80.9 63.1 59.0 54.3 84.2 86.8 85.2 105.2 89.0 91.9 86.0 88.4 91.3 87.7 90.4 91.3 84.8 83.3 89.1 51.2 64.6 297.2 322.0 384.6 74.0 48.5 117.1 71.8 120.7 87.2 218.6 125.0 6.2 309.5 70.3 182.0 328.7 216.5 350.3 102.8 110.9 133.0 133.4 45.0 50.7 219.5 366.9 171.6 105.0 162.8 50.7 67.1 102.4 183.7 375.3 58.9 53.4 200.4 262.4 122.9 221.6 911.4 145.7 153.3 197.5 83.4 110.5 144.7 41.2 50.3 71.7 234.0 148.2 212.9 107.1 323.2 168.4 441.7 162.4 45.6 72.3 103.8 210.9 193.8 106.7 90.7 293.8 703.8 70.5 76.5 168.4 477.9 ACTR2 ARP2 ENSG00000138071 "Actin related protein 2" P61160 2 65227788-65271253 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005083, HPA015050" Approved Approved Cytosol NA NA 35000000 "Cluster 14: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "CAB005083: AB_2221848, HPA015050: AB_1844556" "unprognostic (2.23e-1)" "unprognostic (1.15e-3)" "unprognostic (3.89e-2)" "unprognostic (2.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (4.50e-4)" "unprognostic (3.88e-2)" "unprognostic (3.16e-2)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (8.59e-2)" "unprognostic (2.36e-3)" "unprognostic (3.18e-2)" "unprognostic (4.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.03e-2)" 113.0 70.7 39.9 216.2 48.3 160.5 77.0 42.2 54.7 81.4 38.3 142.4 104.8 70.1 64.5 111.0 53.7 90.9 64.9 51.4 47.2 85.6 108.9 115.9 246.4 43.6 41.4 43.9 61.7 61.9 25.0 109.6 42.9 71.7 139.1 70.2 64.9 64.1 60.4 69.4 118.2 104.4 48.0 172.0 107.3 46.2 45.5 182.2 73.1 64.9 256.3 128.6 46.0 61.1 267.3 221.2 205.5 224.5 218.8 296.1 213.2 367.3 284.1 280.0 193.6 249.3 214.2 590.6 181.8 406.9 174.3 196.8 179.8 258.3 459.4 337.2 150.8 652.1 147.6 235.9 248.0 619.8 731.6 256.5 201.6 312.2 297.7 228.6 356.6 202.0 282.1 209.2 480.0 198.2 325.4 330.6 173.2 245.7 157.5 347.9 266.0 248.6 328.7 341.7 105.2 171.6 239.0 273.5 262.0 186.9 167.6 417.4 467.9 306.5 184.8 202.8 408.9 158.0 155.2 824.1 264.4 598.7 353.9 325.4 182.4 220.6 104.3 241.4 111.8 97.1 91.1 98.6 213.1 80.4 70.3 99.2 258.2 104.1 273.3 79.3 113.9 344.5 39.9 48.3 42.2 54.7 51.4 47.2 43.6 41.4 42.9 48.0 45.5 61.1 187.1 86.6 112.7 32.3 202.4 74.7 88.0 93.0 70.0 81.8 75.8 57.1 76.3 51.5 93.2 97.5 66.7 81.8 257.9 280.5 50.9 100.5 37.5 114.5 131.4 131.0 110.8 89.8 152.6 129.0 138.6 96.0 105.0 163.2 191.1 77.8 113.6 102.9 277.7 104.3 106.0 166.5 85.5 450.1 311.8 92.5 65.3 352.0 88.9 97.4 378.9 87.9 207.0 38.7 68.9 164.4 195.3 74.4 119.7 114.9 131.1 89.0 127.7 82.4 124.9 63.3 122.8 31.4 41.8 102.5 90.6 124.4 203.2 74.2 172.8 181.7 SPRED2 "FLJ21897, FLJ31917, Spred-2" ENSG00000198369 "Sprouty related EVH1 domain containing 2" Q7Z698 2 65310851-65432637 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 108.7;Excitatory neurons: 138.5;Inhibitory neurons: 122.4;Oligodendrocyte precursor cells: 124.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 1.9;plasmacytoid DC: 4.2" "Group enriched" "Detected in many" 4 "dendritic cells: 4.2;NK-cells: 1.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038256, HPA064394" Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA038256: , HPA064394: AB_2732712" "unprognostic (1.49e-1)" "unprognostic (5.95e-3)" "unprognostic (3.46e-2)" "unprognostic (4.40e-3)" "unprognostic (8.94e-2)" "unprognostic (1.63e-1)" "unprognostic (2.90e-2)" "unprognostic (9.94e-2)" "unprognostic (9.07e-2)" "unprognostic (4.25e-1)" "unprognostic (5.05e-2)" "unprognostic (1.92e-1)" "unprognostic (2.37e-2)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (7.21e-3)" "unprognostic (5.43e-2)" 23.9 11.4 12.0 9.7 15.3 7.0 21.7 11.8 22.8 13.5 5.6 16.5 14.9 16.5 8.6 10.9 13.3 13.2 14.7 14.4 11.4 13.7 24.8 18.4 14.0 14.4 12.5 14.0 18.0 16.7 11.5 15.8 11.2 12.3 16.1 10.9 15.9 10.8 8.0 11.3 13.7 11.5 11.1 8.5 19.8 7.4 13.3 28.7 17.9 13.9 15.4 15.5 14.0 12.7 60.4 32.9 32.2 32.4 41.1 40.9 22.2 16.1 25.2 10.9 14.5 43.4 16.4 41.2 9.2 20.8 29.2 18.7 18.2 37.2 21.9 52.3 11.6 9.7 9.1 45.2 21.0 25.7 18.8 33.1 22.2 37.2 36.9 22.9 6.9 24.9 39.1 16.9 17.7 40.9 22.6 26.7 16.1 43.4 35.4 17.1 28.6 24.2 34.1 52.3 13.1 45.1 18.1 14.8 44.2 20.1 15.1 23.7 11.4 27.6 35.8 23.8 27.4 33.2 13.8 73.7 44.7 27.1 54.2 0.0 0.2 0.0 0.6 0.7 0.0 0.0 0.1 0.5 0.4 0.0 0.1 0.1 0.6 1.9 0.3 4.2 0.0 0.7 12.0 15.3 11.8 22.8 14.4 11.4 14.4 12.5 11.2 11.1 13.3 12.7 49.7 19.2 16.0 108.7 1.8 39.9 29.0 12.0 41.5 17.8 22.7 17.7 7.5 14.3 6.6 9.2 6.2 11.0 3.3 32.0 13.7 11.0 1.5 16.8 11.4 18.6 11.4 1.7 138.5 8.6 8.4 21.0 14.8 35.0 1.3 2.8 13.9 14.1 6.7 25.2 122.4 24.1 8.2 7.5 67.6 4.1 17.1 10.2 19.6 68.4 26.0 7.9 0.0 124.1 23.2 13.9 21.5 12.4 0.5 23.4 17.1 7.4 7.2 9.8 26.3 17.0 17.4 3.9 10.4 16.6 16.8 3.0 3.8 4.7 10.9 24.0 MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Disease related genes, Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 110.5;Endometrial stromal cells: 117.2;Horizontal cells: 82.4;Oligodendrocytes: 227.5;Rod photoreceptor cells: 121.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.5;HeLa: 29.3;HHSteC: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 51: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB011521: AB_776272, HPA056000: AB_2683004, HPA058641: AB_2683784" "unprognostic (6.84e-2)" "unprognostic (1.08e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-1)" "prognostic favorable (2.70e-5)" "unprognostic (2.45e-2)" "unprognostic (7.78e-3)" "unprognostic (2.36e-2)" "unprognostic (5.91e-2)" "unprognostic (1.07e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (6.52e-2)" "unprognostic (9.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-2)" 21.8 52.0 7.0 12.0 10.4 2.5 13.1 33.1 8.7 89.8 4.0 72.2 5.7 84.0 23.0 23.0 82.7 15.7 13.8 4.1 8.0 9.5 3.8 34.1 2.3 14.0 10.5 43.6 45.0 6.9 1.6 15.3 18.1 33.8 12.2 43.0 39.0 35.4 5.6 11.7 19.7 50.0 11.3 18.4 31.7 2.9 8.8 4.7 5.8 3.4 6.9 39.2 55.9 19.4 0.3 1.6 12.4 2.7 16.3 10.9 1.6 17.0 43.5 14.4 15.2 1.5 12.3 0.0 4.2 13.5 0.8 2.0 7.7 7.5 14.1 0.0 6.9 20.3 29.3 3.1 31.3 0.0 5.8 9.6 8.8 6.0 2.4 11.5 6.7 3.3 1.8 0.0 0.6 0.7 1.8 0.4 0.3 1.6 1.8 0.0 3.3 3.6 1.2 4.0 3.8 26.2 3.0 1.0 1.3 9.4 1.3 2.5 2.1 3.1 4.8 2.3 4.8 3.4 1.1 0.1 2.3 18.2 0.8 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.5 1.6 0.0 1.3 0.1 2.1 7.0 10.4 33.1 8.7 4.1 8.0 14.0 10.5 18.1 11.3 8.8 19.4 0.6 0.0 0.5 55.5 0.2 3.2 11.9 10.1 15.4 19.8 2.5 1.4 18.7 1.5 8.3 0.0 110.5 5.7 0.4 2.1 0.0 21.6 10.3 36.8 117.2 4.4 1.2 5.9 6.5 17.5 1.6 19.4 7.1 27.9 0.0 0.2 16.1 1.8 2.2 82.4 5.8 0.7 10.2 1.4 1.9 14.1 34.5 10.3 3.6 15.9 0.5 21.4 1.0 54.3 227.5 20.1 67.3 28.2 0.0 2.4 0.6 3.2 6.8 121.0 19.7 6.7 12.5 2.7 2.0 17.9 2.3 1.9 2.0 6.3 1.2 18.8 ETAA1 ETAA16 ENSG00000143971 "ETAA1 activator of ATR kinase" Q9NY74 2 67397322-67412089 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035048, HPA035049" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA035048: AB_10670300, HPA035049: AB_2674430" "unprognostic (1.23e-1)" "unprognostic (2.56e-1)" "unprognostic (5.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (3.39e-2)" "unprognostic (6.47e-2)" "unprognostic (5.53e-2)" "unprognostic (1.12e-2)" "unprognostic (8.33e-2)" "unprognostic (9.89e-2)" "unprognostic (1.87e-1)" "unprognostic (8.52e-3)" "unprognostic (9.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.01e-2)" "unprognostic (1.14e-2)" 4.7 11.1 2.7 4.3 3.1 3.9 7.1 4.0 3.3 6.7 3.9 5.0 3.6 6.9 6.2 5.9 6.6 4.3 3.9 2.4 2.7 6.1 5.3 5.4 6.5 2.9 2.8 7.3 8.2 6.1 3.3 4.2 2.9 5.0 4.4 5.7 6.2 3.9 3.5 6.2 5.5 5.1 2.7 5.5 5.2 4.6 2.8 6.3 6.3 3.1 5.0 5.1 6.6 3.5 7.9 5.9 10.2 9.0 7.6 10.4 8.0 8.2 10.8 8.7 8.3 4.8 9.3 14.8 4.4 6.8 12.1 9.5 8.9 10.0 12.3 8.6 6.8 8.1 14.7 7.1 7.2 8.3 7.4 8.3 13.8 6.4 9.7 13.7 13.8 11.8 6.8 6.1 12.0 3.5 12.3 9.0 10.3 12.7 6.3 8.6 16.0 6.8 10.5 5.1 8.5 16.7 8.4 7.6 8.0 9.9 6.6 4.0 9.6 11.6 8.9 5.6 9.8 6.8 6.5 11.6 10.9 8.6 9.0 1.3 1.1 0.9 2.2 1.8 2.4 3.5 2.0 1.3 1.4 3.6 2.7 2.4 0.1 2.0 2.6 2.0 3.2 1.3 2.7 3.1 4.0 3.3 2.4 2.7 2.9 2.8 2.9 2.7 2.8 3.5 7.7 22.4 21.0 10.4 7.6 2.4 7.9 8.3 6.8 5.1 8.8 8.4 10.1 15.7 9.1 12.9 0.0 6.6 9.1 3.5 11.7 17.8 0.6 15.0 15.0 7.8 10.7 13.7 6.3 18.4 6.3 10.9 6.6 11.1 6.3 15.4 10.4 8.9 4.8 5.0 6.6 7.1 2.0 5.1 1.5 1.9 12.2 4.8 1.8 2.8 9.4 6.5 15.5 15.1 13.6 20.4 4.7 13.2 7.0 8.0 5.9 15.0 16.6 4.6 0.0 8.9 7.3 12.7 8.2 7.9 2.6 2.1 7.2 14.1 7.0 6.1 C1D "LRP1, Rrp47, SUN-CoR, SUNCOR" ENSG00000197223 "C1D nuclear receptor corepressor" Q13901 2 68041130-68110948 "Predicted intracellular proteins" "Apoptosis, rRNA processing, Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037413, HPA037588" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 34: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "HPA037413: AB_2675463, HPA037588: AB_10672907" "unprognostic (1.84e-1)" "unprognostic (1.85e-1)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.03e-1)" "unprognostic (1.49e-2)" "unprognostic (4.01e-3)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.98e-1)" "unprognostic (3.90e-2)" "unprognostic (1.29e-2)" "unprognostic (4.24e-3)" "unprognostic (6.18e-2)" "unprognostic (2.50e-1)" "unprognostic (8.80e-2)" "unprognostic (1.01e-1)" 21.7 25.3 11.6 17.0 11.8 48.1 21.4 11.9 19.0 19.9 12.8 19.1 16.6 20.0 17.0 19.3 18.3 14.7 22.2 12.0 12.8 31.5 33.4 19.0 21.4 11.3 11.8 19.3 15.8 24.0 15.3 17.5 11.6 19.5 14.7 16.6 18.7 15.5 46.9 17.5 18.5 13.7 12.0 21.7 21.4 14.8 12.0 17.5 19.6 31.9 16.5 17.4 28.2 13.9 36.6 20.3 22.0 21.0 22.2 27.0 29.6 48.7 28.1 29.3 22.4 40.8 45.0 45.2 27.2 28.9 28.1 18.0 24.7 20.4 43.1 43.0 36.6 43.5 17.6 46.3 22.3 68.1 54.4 25.0 32.4 22.1 20.9 36.3 22.0 41.4 44.8 41.1 26.6 22.2 51.3 69.6 25.4 29.8 24.4 29.6 28.3 39.9 28.2 29.2 20.5 25.4 15.1 30.0 51.6 26.7 22.2 41.2 30.9 27.9 34.5 34.0 38.9 38.0 40.8 58.6 38.9 41.3 34.2 45.3 17.6 43.7 19.0 23.3 22.5 24.2 22.0 16.6 20.6 21.3 23.4 24.3 34.9 30.3 25.2 19.2 25.3 15.2 11.6 11.8 11.9 19.0 12.0 12.8 11.3 11.8 11.6 12.0 12.0 13.9 65.2 76.9 47.9 13.1 70.7 85.0 83.2 132.8 33.6 34.3 52.9 58.4 36.5 64.3 86.3 64.4 22.9 98.9 76.2 48.1 234.8 83.4 52.4 53.7 47.2 42.9 51.6 121.2 17.7 59.4 82.7 60.2 44.9 46.6 44.3 32.8 43.5 81.7 87.5 35.3 15.9 42.6 109.9 61.9 46.1 21.7 55.6 66.9 56.9 8.4 80.1 57.4 88.6 14.1 21.9 65.6 63.3 59.0 58.5 78.1 57.0 251.4 95.4 36.8 98.6 54.2 65.3 164.5 100.3 44.5 86.2 107.8 62.9 52.2 32.8 109.0 WDR92 "FLJ31741, Monad" ENSG00000243667 "WD repeat domain 92" Q96MX6 2 68122936-68157549 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 47.9;Respiratory ciliated cells: 40.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035335, HPA035336" Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA035335: AB_10959456, HPA035336: AB_10964348" "unprognostic (3.55e-2)" "unprognostic (3.42e-3)" "unprognostic (6.80e-2)" "unprognostic (1.69e-2)" "unprognostic (1.31e-1)" "unprognostic (3.20e-2)" "unprognostic (3.76e-3)" "unprognostic (2.51e-2)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (4.91e-2)" "unprognostic (3.61e-1)" "unprognostic (3.56e-3)" "unprognostic (9.86e-2)" "unprognostic (7.23e-2)" "unprognostic (4.07e-1)" "unprognostic (3.15e-2)" 6.0 7.0 4.9 6.6 6.4 3.6 8.6 7.6 5.5 5.4 10.4 6.1 6.3 7.4 16.0 7.0 11.1 5.3 9.0 5.0 4.9 5.5 5.2 5.8 9.7 5.7 7.2 6.9 4.3 7.2 4.7 5.7 4.6 8.1 8.0 6.9 6.4 6.8 11.4 10.5 5.3 7.5 5.2 8.2 5.9 8.0 4.7 8.1 8.3 9.1 8.9 5.0 5.1 5.5 15.3 9.4 12.0 12.6 14.5 14.7 10.3 11.6 10.1 12.1 12.8 7.0 12.5 16.5 3.7 10.3 16.5 15.0 13.0 8.8 15.6 11.2 13.8 16.9 13.1 8.0 7.0 18.5 5.2 9.4 11.5 10.0 8.6 12.9 11.7 15.2 11.3 11.1 14.3 7.3 13.2 18.6 12.2 12.8 12.9 15.9 15.3 14.1 12.5 8.6 12.4 10.6 8.6 15.5 9.6 11.8 11.9 12.1 13.6 18.4 7.4 11.6 10.1 7.6 11.6 11.6 17.3 17.6 9.3 0.7 2.3 1.7 3.2 2.5 4.2 5.3 3.4 3.8 2.7 4.9 4.0 5.0 1.0 6.3 1.8 5.1 4.0 2.1 4.9 6.4 7.6 5.5 5.0 4.9 5.7 7.2 4.6 5.2 4.7 5.5 7.8 3.2 10.9 5.9 5.2 3.4 4.7 6.5 2.2 28.7 5.6 5.6 3.1 1.5 11.1 5.5 47.9 13.6 12.2 1.3 1.9 6.7 5.8 26.3 6.8 7.4 0.0 7.0 17.9 6.5 9.2 5.7 1.5 4.3 13.3 9.7 8.2 6.3 7.3 11.8 16.4 3.3 4.1 3.5 1.2 2.8 7.8 3.5 1.8 8.4 7.2 12.0 6.2 14.1 11.6 6.2 2.9 9.4 2.0 3.3 3.7 6.7 40.2 21.9 6.6 9.0 5.9 26.0 15.2 1.8 4.1 5.1 3.6 9.4 6.0 2.1 PNO1 "KHRBP1, RRP20" ENSG00000115946 "Partner of NOB1 homolog" Q9NRX1 2 68157888-68176238 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056928 Supported Nucleoplasm,Nucleoli NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Nucleoplasm "HPA056928: " "unprognostic (1.81e-3)" "unprognostic (4.83e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (5.88e-2)" "unprognostic (1.66e-3)" "prognostic unfavorable (3.04e-8)" "unprognostic (5.82e-2)" "unprognostic (2.59e-2)" "unprognostic (1.16e-1)" "unprognostic (9.13e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-2)" "unprognostic (1.42e-1)" "unprognostic (2.58e-1)" "unprognostic (3.74e-2)" "unprognostic (7.66e-2)" 15.1 14.2 6.4 12.1 8.0 19.5 11.6 7.0 11.8 7.6 6.9 9.7 7.6 9.8 11.2 11.1 8.8 9.9 10.2 12.0 7.3 14.1 12.6 8.6 12.6 6.7 6.9 7.0 12.7 12.5 7.1 12.7 6.8 10.0 9.1 19.0 7.1 10.8 20.1 9.1 6.7 11.5 6.7 8.2 8.8 8.9 6.9 8.1 12.5 12.6 12.2 19.8 7.6 7.4 37.8 40.1 18.5 30.5 22.5 18.3 46.0 34.7 23.0 39.1 27.8 77.9 21.9 51.4 28.5 23.6 54.0 31.6 60.6 41.9 61.3 35.2 40.6 49.7 17.4 58.2 34.6 40.2 22.4 24.1 30.2 39.4 45.0 11.3 29.1 32.7 69.7 27.3 35.7 27.4 39.9 38.1 52.0 68.7 43.1 33.3 45.2 54.8 29.8 31.7 32.7 24.0 26.1 32.4 57.8 29.7 22.9 22.4 21.2 44.2 48.0 40.1 97.9 21.6 33.1 78.1 36.3 59.1 62.1 0.9 12.6 2.8 12.2 18.1 19.1 19.2 13.8 14.4 16.8 14.5 16.0 14.6 2.4 15.0 13.0 11.8 16.0 21.3 6.4 8.0 7.0 11.8 12.0 7.3 6.7 6.9 6.8 6.7 6.9 7.4 23.7 16.0 13.2 3.3 29.9 83.2 62.8 29.5 25.6 22.7 18.6 18.4 11.9 18.6 36.2 7.3 12.5 39.5 20.2 7.9 19.6 36.7 33.5 28.7 37.7 25.5 17.3 21.4 10.6 29.8 43.5 28.3 9.7 20.9 31.6 13.6 12.5 15.8 26.0 18.5 9.0 12.1 30.5 10.4 38.7 7.7 12.5 20.7 12.4 4.7 18.9 21.0 14.4 7.1 10.4 29.1 5.8 16.6 27.8 56.6 4.6 34.7 28.6 51.3 6.6 40.4 29.6 28.9 41.7 21.0 56.1 47.6 25.7 20.5 20.2 37.6 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 CNRIP1 "C2orf32, CRIP1, CRIP1a, CRIP1b, DKFZP566K1924" ENSG00000119865 "Cannabinoid receptor interacting protein 1" Q96F85 2 68284171-68320051 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.2;Erythroid cells: 116.2;granulocytes: 122.9" "Cancer enhanced" "Detected in all" "glioma: 14.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 109 "basophil: 12.2" "Lineage enriched" "Detected in single" 109 "granulocytes: 12.2" "Cell line enhanced" "Detected in many" "HEL: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035337 Approved Cytosol NA NA 54000 "Cluster 38: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "HPA035337: AB_10601359" "unprognostic (1.23e-1)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (2.85e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (6.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.86e-2)" "unprognostic (4.58e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (1.04e-2)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (3.38e-3)" 27.4 6.4 59.0 5.9 62.3 6.1 20.2 50.9 71.6 30.1 29.6 17.1 3.5 22.4 6.1 5.3 24.2 8.5 16.0 65.1 51.8 10.3 2.9 18.3 5.1 40.4 45.1 31.2 3.0 1.8 15.4 12.1 44.3 15.1 4.6 29.6 5.8 8.9 6.6 8.1 10.9 9.3 44.7 10.2 10.6 2.6 52.7 2.7 8.9 7.0 2.9 20.7 19.2 51.8 0.0 1.1 9.0 0.0 34.1 24.6 0.1 34.5 26.6 30.6 22.3 0.0 0.0 0.0 1.2 33.2 22.6 0.0 0.7 0.2 32.6 0.0 8.1 158.7 2.3 0.0 34.7 0.1 21.7 22.1 0.0 20.0 11.5 18.7 47.8 0.0 0.2 0.1 23.4 0.1 0.0 0.4 16.3 0.0 15.6 0.0 13.2 0.0 0.0 0.0 45.8 47.8 2.2 0.0 28.3 0.1 0.0 1.7 51.4 21.1 12.9 18.5 51.0 0.0 0.0 0.1 16.9 0.0 15.5 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 59.0 62.3 50.9 71.6 65.1 51.8 40.4 45.1 44.3 44.7 52.7 51.8 50.2 0.0 4.3 15.0 0.6 12.9 0.4 0.0 4.6 72.2 0.6 1.7 2.1 0.0 0.6 0.0 22.9 1.2 0.1 0.0 0.0 0.4 0.7 1.9 30.4 60.6 0.0 116.2 48.8 0.2 9.3 44.4 0.5 0.6 122.9 1.3 36.4 0.8 56.3 28.6 39.5 0.0 0.0 25.7 40.9 2.6 45.4 13.9 37.4 16.9 2.5 42.0 0.0 24.1 19.6 0.5 0.0 42.5 0.5 1.2 0.0 0.1 0.0 54.3 46.0 18.7 41.9 0.7 0.5 0.7 10.7 2.1 3.8 27.3 0.0 1.0 PLEK P47 ENSG00000115956 Pleckstrin P08567 2 68365282-68397453 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 604.8" "Cell type enhanced" "Detected in many" "dendritic cells: 310.7;Hofbauer cells: 220.3;Kupffer cells: 213.9;Langerhans cells: 456.5;Macrophages: 412.7;monocytes: 178.3;NK-cells: 355.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 552.9;HL-60: 126.7;HMC-1: 202.5;NB-4: 187.5;THP-1: 215.6;U-266/84: 147.8;U-698: 147.1;U-937: 342.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031838, HPA057341" Enhanced Approved Nucleoli NA NA 380000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoli "HPA031838: AB_10602146, HPA057341: AB_2732609" "unprognostic (2.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.52e-3)" "unprognostic (3.52e-1)" "unprognostic (3.08e-2)" "unprognostic (4.67e-2)" "unprognostic (3.40e-2)" "unprognostic (4.00e-2)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (1.22e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (3.57e-1)" "unprognostic (4.42e-2)" "unprognostic (2.03e-1)" "unprognostic (1.56e-1)" 36.4 9.8 4.9 99.4 7.1 604.8 8.2 6.0 10.0 6.9 6.5 13.2 10.4 4.7 3.3 6.0 7.2 21.0 5.4 4.9 5.3 4.0 27.5 35.6 129.9 8.0 6.1 2.6 2.7 2.7 1.9 29.2 8.1 4.2 18.8 0.5 5.7 3.1 1.7 3.4 13.0 22.2 7.3 93.5 11.3 3.2 7.2 33.7 3.8 5.2 118.2 52.3 2.5 12.3 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 93.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 552.9 0.0 0.0 0.0 126.7 202.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 58.9 0.0 0.0 0.2 187.5 0.0 0.0 0.0 1.5 0.1 27.3 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.0 0.0 215.6 0.1 0.0 0.4 0.1 0.5 7.9 147.8 147.1 0.2 342.5 0.1 231.9 297.5 429.2 298.5 351.6 157.6 157.7 52.2 218.7 229.6 103.6 14.5 161.8 573.9 249.5 390.8 474.8 5.7 606.9 4.9 7.1 6.0 10.0 4.9 5.3 8.0 6.1 8.1 7.3 7.2 12.3 3.4 19.2 24.6 0.0 77.0 6.5 0.3 0.0 0.0 0.0 1.4 3.7 2.3 1.5 15.5 1.8 0.0 1.2 310.7 0.0 0.0 0.2 1.5 0.2 0.3 6.3 0.0 21.9 0.6 0.6 1.8 10.2 1.5 0.3 62.0 0.0 5.7 1.5 220.3 0.0 0.2 0.0 0.0 213.9 456.5 5.1 0.6 412.7 17.8 20.6 178.3 0.0 355.3 0.0 0.1 0.1 0.1 0.4 48.4 0.0 0.0 0.7 13.1 0.1 13.1 1.1 1.8 0.8 0.9 0.6 6.7 2.6 78.3 0.4 0.0 0.3 FBXO48 ENSG00000204923 "F-box protein 48" Q5FWF7 2 68459422-68467294 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Alveolar cells type 2: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA049775, HPA054782" Uncertain Approved "Nuclear bodies" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Non-specific - Microtubule organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "HPA049775: AB_2680874, HPA054782: AB_2682599" "unprognostic (2.90e-1)" "unprognostic (2.62e-2)" "unprognostic (2.25e-1)" "unprognostic (2.75e-3)" "unprognostic (6.56e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-1)" "unprognostic (4.74e-2)" "unprognostic (6.01e-3)" "unprognostic (3.92e-2)" "unprognostic (3.81e-2)" "unprognostic (2.33e-1)" "unprognostic (2.09e-2)" "unprognostic (6.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.39e-3)" "unprognostic (1.89e-2)" 1.1 1.2 1.3 1.4 1.8 0.7 1.3 1.5 1.5 1.1 1.2 1.1 1.8 0.8 1.1 1.1 0.7 0.8 0.7 1.3 1.2 1.4 2.0 1.0 1.7 1.5 1.4 1.7 0.8 1.3 0.5 1.2 1.7 0.8 1.2 3.0 1.3 0.7 3.1 2.5 1.5 0.6 1.2 1.8 1.3 1.0 1.7 1.2 1.1 1.8 1.8 0.7 0.9 2.7 2.1 0.7 1.3 0.9 1.6 1.8 0.9 1.5 1.8 1.4 1.6 1.0 0.9 2.6 1.0 0.7 1.9 1.1 1.2 1.2 2.7 3.5 1.3 1.3 0.7 0.5 0.7 0.6 1.5 0.8 2.1 2.0 1.7 0.7 0.6 4.3 0.6 4.9 1.1 0.4 1.5 1.9 0.7 1.4 1.0 1.3 2.3 1.7 1.1 0.6 1.3 0.9 0.7 0.3 1.7 1.1 0.4 0.6 0.6 1.6 1.5 2.0 1.6 3.9 2.5 1.1 1.0 1.1 1.2 2.6 0.7 0.9 1.0 0.7 1.0 0.9 1.7 1.0 0.4 1.0 1.2 1.2 1.4 1.0 1.3 0.9 2.1 0.6 1.3 1.8 1.5 1.5 1.3 1.2 1.5 1.4 1.7 1.2 1.7 2.7 9.1 32.1 52.0 1.3 6.4 7.1 5.0 3.1 9.1 3.9 7.7 10.4 11.7 7.2 16.3 5.5 2.1 4.2 4.5 7.1 11.7 3.2 1.7 4.0 3.1 8.2 3.0 4.0 0.8 3.3 3.5 6.8 3.1 4.1 12.6 2.1 5.3 7.1 4.1 3.3 0.8 6.2 0.0 5.1 6.6 1.0 4.1 8.7 1.8 0.0 2.5 2.2 2.1 1.5 1.7 3.1 2.7 1.5 5.8 3.4 7.4 9.2 12.9 5.7 0.0 5.5 3.9 18.0 11.1 6.7 8.0 1.6 8.1 2.8 3.5 3.9 APLF "C2orf13, MGC47799, Xip1, ZCCHH1" ENSG00000169621 "Aprataxin and PNKP like factor" Q8IW19 2 68467572-68655862 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 103.7;Late spermatids: 164.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 7.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029396, HPA034642, HPA034643" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA029396: AB_10610285, HPA034642: AB_2674259, HPA034643: AB_10602431" "unprognostic (9.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.14e-1)" "unprognostic (4.29e-3)" "unprognostic (5.18e-3)" "unprognostic (2.39e-3)" "unprognostic (3.24e-1)" "unprognostic (1.46e-1)" "unprognostic (4.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.25e-3)" "unprognostic (3.28e-1)" "unprognostic (5.02e-3)" "unprognostic (8.44e-2)" "unprognostic (5.95e-2)" "unprognostic (1.35e-2)" "unprognostic (1.85e-3)" 1.2 1.1 2.0 0.8 3.2 0.7 1.4 0.1 2.2 1.1 0.0 1.1 0.6 1.3 1.0 1.5 0.5 1.0 0.9 2.7 1.9 0.9 1.5 0.9 1.2 0.7 2.2 0.9 0.6 0.9 0.4 1.8 1.0 1.1 0.8 0.4 1.1 1.3 1.1 2.3 0.5 1.1 0.9 0.8 0.7 1.0 1.5 0.8 1.1 1.3 1.2 1.0 1.4 3.2 1.8 0.3 1.7 1.8 3.4 4.4 1.0 1.7 3.6 1.1 1.4 0.7 1.1 3.4 1.1 1.7 2.2 0.5 0.3 2.7 2.7 2.9 0.4 2.5 0.1 0.4 1.5 0.8 2.4 2.4 2.2 1.7 2.5 2.2 0.8 1.7 0.2 2.8 1.2 0.2 1.3 3.1 1.1 1.8 0.9 1.5 0.6 1.6 2.4 1.0 0.4 1.1 1.8 0.0 1.7 2.6 0.0 0.6 1.2 3.4 0.6 1.5 1.3 2.0 0.9 2.4 1.5 0.8 2.0 7.0 0.5 1.9 0.4 0.7 0.6 0.6 0.8 0.7 0.8 0.5 0.8 0.4 0.0 1.0 0.6 0.7 1.4 0.5 2.0 3.2 0.1 2.2 2.7 1.9 0.7 2.2 1.0 0.9 1.5 3.2 3.6 3.2 2.6 14.0 3.1 2.4 2.4 4.4 8.0 0.5 2.4 3.6 3.5 0.0 2.9 0.0 2.1 6.3 2.6 0.3 0.0 3.5 103.7 1.4 4.0 3.1 3.5 3.4 21.8 1.9 2.2 3.2 4.6 1.7 0.0 3.9 2.2 1.2 2.2 3.3 3.2 0.7 2.0 1.9 2.6 164.1 4.4 2.3 0.0 9.4 4.2 0.5 3.1 22.6 29.0 1.4 0.5 1.9 6.4 2.8 0.2 2.2 1.3 0.2 0.0 4.8 4.7 7.7 4.8 5.0 3.3 4.9 1.8 2.2 0.7 1.5 PROKR1 "GPR73, GPR73a, PKR1, ZAQ" ENSG00000169618 "Prokineticin receptor 1" Q8TCW9 2 68643579-68658251 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.6;epididymis: 3.5" "Cell type enhanced" "Detected in single" "Adipocytes: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 2.0" "Low region specificity" "Detected in all" HPA029396 Uncertain NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA029396: AB_10610285" "unprognostic (5.46e-2)" "unprognostic (1.60e-2)" "unprognostic (8.75e-2)" "unprognostic (4.99e-4)" "unprognostic (1.18e-1)" "unprognostic (2.55e-3)" "unprognostic (1.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.85e-1)" "unprognostic (4.52e-2)" "unprognostic (1.89e-1)" "unprognostic (9.72e-2)" "unprognostic (8.96e-7)" "unprognostic (4.07e-2)" "unprognostic (2.53e-1)" "unprognostic (4.19e-1)" "unprognostic (7.22e-2)" 1.6 1.1 0.0 0.2 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.6 0.4 0.5 0.4 0.1 0.1 1.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARHGAP25 KIAA0053 ENSG00000163219 "Rho GTPase activating protein 25" P42331 2 68679601-68826833 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.8" "Cell type enhanced" "Detected in many" "B-cells: 88.7;granulocytes: 210.8;Microglial cells: 88.1;NK-cells: 103.0;T-cells: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 657.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 66.7;HMC-1: 256.1;NB-4: 47.3;U-266/70: 50.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035346, HPA061395" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Vesicles" "HPA035346: AB_10601116, HPA061395: AB_2684501" "unprognostic (1.13e-3)" "prognostic favorable (7.72e-4)" "unprognostic (2.45e-2)" "unprognostic (4.44e-3)" "unprognostic (8.07e-2)" "unprognostic (1.36e-2)" "unprognostic (1.13e-1)" "unprognostic (6.16e-3)" "unprognostic (2.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.00e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.10e-1)" "unprognostic (4.26e-2)" "unprognostic (3.61e-1)" "unprognostic (4.49e-2)" 11.1 5.2 5.2 38.8 5.4 37.4 8.0 5.6 7.9 6.0 5.1 7.2 6.2 6.7 22.7 4.3 4.7 11.7 6.7 5.2 5.6 7.1 10.1 21.3 71.4 7.6 6.0 16.7 2.1 2.3 3.5 10.7 6.7 5.0 9.6 0.6 5.1 3.8 3.2 6.2 23.3 8.3 7.1 72.8 8.8 2.5 7.0 27.3 5.1 8.4 67.3 11.9 4.7 8.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 20.8 0.5 0.0 0.1 2.5 0.0 20.5 0.0 2.3 0.0 66.7 0.0 0.0 1.0 14.8 256.1 0.2 2.4 0.4 8.1 0.0 0.0 22.2 0.4 23.6 0.0 0.0 17.2 47.3 1.2 0.2 0.0 18.7 4.3 0.8 0.0 5.4 4.1 0.6 0.2 0.0 1.4 1.4 0.0 12.3 3.5 0.1 0.9 0.1 0.5 50.8 29.0 16.8 0.2 33.3 0.3 234.8 60.8 528.7 171.3 75.9 107.0 156.4 76.2 150.0 37.4 100.8 54.2 95.2 657.3 170.6 94.8 52.3 102.0 132.0 5.2 5.4 5.6 7.9 5.2 5.6 7.6 6.0 6.7 7.1 7.0 8.4 14.1 3.2 15.0 0.3 88.7 5.6 12.4 2.9 5.7 0.8 0.7 6.1 1.4 1.5 2.0 0.0 0.0 0.5 35.1 0.1 1.9 0.1 1.8 0.7 0.6 16.6 3.0 11.6 15.5 0.2 0.4 3.5 2.0 0.4 210.8 0.1 15.4 1.0 48.6 0.0 0.9 0.5 2.0 27.3 12.8 3.6 1.5 22.6 1.8 88.1 40.9 0.5 103.0 0.5 0.9 0.0 0.1 2.6 34.7 1.2 0.0 0.2 5.2 0.2 6.6 0.8 2.1 0.6 1.3 2.5 1.4 0.3 53.7 1.8 0.2 2.5 BMP10 ENSG00000163217 "Bone morphogenetic protein 10" O95393 2 68860909-68871397 "Predicted secreted proteins" "Cell adhesion" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "heart muscle: 447.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "JURKAT: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 230000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.74e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 447.8 0.0 0.0 0.0 6.6 0.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GKN2 "blottin, BRICD1B, GDDR, PRO813, TFIZ1, VLTI465" ENSG00000183607 "Gastrokine 2" Q86XP6 2 68945232-68952893 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 57 "stomach 1: 4612.5" "Cell type enriched" "Detected in some" 22 "Gastric mucus-secreting cells: 2770.2" "Cancer enriched" "Detected in some" 8 "stomach cancer: 43.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;HaCaT: 1.1;HMC-1: 2.0;MOLT-4: 1.6;NTERA-2: 2.3;PC-3: 4.5;U-2 OS: 1.6;U-266/70: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057765 Enhanced "Secreted to digestive system" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA057765: AB_2683520" "unprognostic (1.81e-1)" "unprognostic (1.44e-4)" "unprognostic (2.22e-1)" 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.4 0.9 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.1 80.8 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 1.4 4612.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 2.3 0.0 4.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.2 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 115.4 109.3 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.9 2770.2 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 121.2 0.0 0.0 10.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 GKN1 "AMP18, BRICD1, CA11" ENSG00000169605 "Gastrokine 1" Q9NS71 2 68974573-68980980 "Plasma proteins, Predicted secreted proteins" Mitogen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1840 "stomach 1: 37425.0" "Cell type enriched" "Detected in some" 28 "Gastric mucus-secreting cells: 9780.9" "Cancer enriched" "Detected in some" 116 "stomach cancer: 255.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 6.5;HMC-1: 17.2;MOLT-4: 12.4;NTERA-2: 16.0;REH: 7.2;U-2 OS: 10.1;U-266/70: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA047684 Enhanced "Secreted to digestive system" NA NA 18000000 "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA047684: AB_2680120" "unprognostic (5.40e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (4.54e-1)" "prognostic favorable (4.53e-4)" 3.0 1.8 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.4 0.0 1.4 0.0 0.3 0.0 3.6 0.4 0.0 1.0 0.0 0.0 1.8 0.8 3.5 0.0 0.0 0.0 0.4 4.8 0.0 0.3 20.3 0.0 0.7 0.3 0.0 0.4 0.1 1.0 0.5 0.4 0.0 0.0 10.4 37425.0 0.4 0.0 1.1 0.2 0.2 0.1 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.0 6.5 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.4 0.0 16.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 10.1 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.3 3.3 9780.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 346.5 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.5 0.0 0.0 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 184.2;Intestinal goblet cells: 244.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 93000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (4.38e-3)" "unprognostic (8.20e-2)" "prognostic favorable (7.13e-5)" "unprognostic (2.97e-1)" "unprognostic (1.32e-1)" "unprognostic (2.40e-2)" "unprognostic (1.08e-2)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (4.84e-2)" "unprognostic (5.00e-2)" "unprognostic (3.83e-2)" "unprognostic (9.49e-2)" "unprognostic (1.78e-1)" "unprognostic (1.63e-1)" "unprognostic (2.58e-1)" 31.2 17.9 6.6 21.5 6.5 15.0 22.4 5.5 7.1 37.8 31.5 74.3 38.4 15.6 41.6 16.4 24.3 32.5 24.8 7.0 11.0 21.6 23.1 17.0 10.6 4.9 10.5 12.0 33.7 26.2 18.9 36.0 10.8 36.7 76.6 10.4 42.4 25.9 10.2 6.0 41.2 23.2 5.3 9.5 64.3 46.6 8.0 10.2 91.8 13.9 15.9 21.8 9.2 6.8 46.6 42.7 34.7 20.9 107.7 75.8 73.5 97.1 94.5 44.7 59.3 109.5 50.5 31.7 31.9 92.9 61.4 22.6 47.1 28.6 73.6 38.4 18.4 38.2 25.0 94.5 123.0 27.9 17.9 47.8 132.5 88.7 158.8 55.5 43.4 29.8 34.8 58.3 85.2 30.9 31.3 22.9 37.0 116.7 27.4 28.2 79.1 18.3 70.6 42.0 25.2 11.9 35.2 52.4 93.7 73.5 22.7 17.2 61.8 37.2 62.3 64.6 47.5 39.5 32.2 25.4 65.7 18.3 46.9 9.2 3.5 4.9 7.5 4.3 7.0 6.4 6.5 8.3 4.7 3.6 6.3 6.2 1.2 5.2 5.2 4.4 5.0 4.2 6.6 6.5 5.5 7.1 7.0 11.0 4.9 10.5 10.8 5.3 8.0 6.8 14.6 51.3 49.5 15.7 29.8 28.4 21.6 31.7 26.7 13.7 50.6 16.5 43.1 42.9 54.5 44.1 12.5 28.6 30.3 184.2 17.6 34.1 123.9 54.4 54.1 17.2 75.1 3.8 49.2 89.5 70.3 37.6 110.1 60.0 24.1 19.2 17.9 53.6 17.0 6.7 56.3 244.0 16.2 10.0 31.4 23.7 23.3 16.0 53.4 27.2 28.1 10.6 13.4 42.7 43.8 66.0 83.3 28.2 82.1 72.3 62.5 30.0 89.7 14.0 19.7 21.6 41.8 134.1 45.3 20.3 21.0 34.3 33.4 15.7 135.3 56.3 NFU1 "CGI-33, HIRIP5, NifU, NIFUC" ENSG00000169599 "NFU1 iron-sulfur cluster scaffold" Q9UMS0 2 69396113-69437628 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 189.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035826 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 38: Heart - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Nucleoplasm "HPA035826: AB_2674803" "unprognostic (4.49e-3)" "unprognostic (5.62e-2)" "unprognostic (5.40e-2)" "unprognostic (1.84e-1)" "unprognostic (2.81e-1)" "unprognostic (2.16e-3)" "unprognostic (2.63e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (1.55e-1)" "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (2.21e-3)" "unprognostic (2.63e-1)" "unprognostic (1.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.87e-1)" 66.8 46.3 36.8 22.5 39.3 33.4 56.8 40.0 56.0 35.6 37.4 51.4 31.3 35.9 51.9 27.9 35.3 29.0 110.4 37.5 40.9 64.2 39.5 31.8 30.0 40.2 39.7 38.0 39.9 43.3 45.1 38.1 41.4 34.3 38.1 56.9 41.2 36.5 140.8 22.3 33.4 33.1 39.9 31.0 43.8 34.6 39.0 22.8 41.9 120.2 29.5 44.8 31.1 42.0 59.3 59.2 56.1 55.5 70.4 75.4 61.6 61.0 62.0 59.0 47.8 114.7 56.9 42.4 30.0 57.0 85.6 25.4 63.7 64.2 79.5 77.8 62.3 43.5 38.2 102.0 70.1 73.7 59.2 58.4 37.2 67.5 41.2 56.0 65.6 41.8 80.1 41.8 99.1 11.9 39.1 119.0 53.9 62.9 64.3 42.6 85.5 15.6 83.5 57.6 45.9 34.3 35.2 32.2 92.5 57.6 40.8 49.4 67.8 71.3 47.1 52.2 80.8 53.8 48.4 23.1 54.2 74.7 55.8 20.2 13.6 25.5 15.9 18.6 15.6 21.7 16.3 18.9 12.4 25.1 16.9 18.6 4.3 18.0 28.5 25.0 24.8 12.3 36.8 39.3 40.0 56.0 37.5 40.9 40.2 39.7 41.4 39.9 39.0 42.0 30.6 32.1 22.5 9.8 37.0 16.2 35.9 96.7 21.1 23.9 33.2 29.6 92.3 37.1 42.6 38.6 12.5 113.9 34.1 34.6 189.8 56.9 111.0 40.0 27.1 34.9 53.3 25.7 15.4 60.9 70.5 30.9 20.4 25.3 58.3 21.6 33.5 32.0 82.6 18.5 18.8 47.7 57.0 35.8 24.0 34.2 34.8 30.2 39.2 10.3 66.8 55.6 46.4 21.1 27.1 50.3 39.7 36.9 25.4 28.8 56.3 163.0 58.9 33.4 46.0 36.9 44.1 82.9 60.4 18.8 14.9 61.3 33.3 42.7 46.3 35.4 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 89.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 777.7;Rod photoreceptor cells: 640.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebral cortex: 31.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 9.1 12.6 0.3 8.1 0.6 12.0 8.1 0.9 31.0 7.1 0.0 7.0 4.6 9.9 9.9 7.4 7.5 5.4 20.4 2.9 0.0 10.5 5.1 10.3 9.0 4.7 2.9 5.5 13.1 89.7 13.7 9.9 3.5 8.6 6.3 28.2 6.7 8.2 13.0 6.3 8.5 7.6 0.0 8.6 12.6 6.7 4.8 13.2 23.4 6.7 7.7 7.8 7.1 4.8 25.1 15.3 14.6 12.3 13.7 14.3 41.0 19.4 16.8 12.0 11.3 15.6 10.0 0.9 4.6 27.6 16.5 11.4 11.7 11.4 27.1 20.6 4.4 13.3 9.0 10.0 11.7 9.5 31.3 12.9 9.6 23.7 30.9 10.2 27.4 12.3 3.2 14.1 22.5 3.7 8.8 5.6 6.4 4.9 8.3 5.8 13.8 2.2 10.0 51.0 4.2 6.6 12.0 8.8 10.2 9.9 5.3 12.9 25.6 26.4 17.5 19.7 19.4 12.9 3.9 1.5 23.0 16.0 19.1 1.4 0.5 0.2 1.4 0.2 1.4 0.1 1.3 1.0 0.3 0.3 1.7 1.5 1.5 1.1 2.2 0.2 1.0 0.5 0.3 0.6 0.9 31.0 2.9 0.0 4.7 2.9 3.5 0.0 4.8 4.8 54.6 35.3 34.2 77.7 13.4 15.9 20.8 15.9 32.5 254.4 42.2 40.9 86.7 102.9 19.3 143.5 777.7 81.6 149.1 130.6 43.0 46.0 23.9 36.6 67.4 56.0 72.1 35.3 265.8 67.4 56.3 29.5 44.9 65.7 21.0 24.4 118.2 38.2 62.4 306.2 327.7 31.6 12.2 128.8 23.5 32.7 38.2 67.1 10.6 156.4 72.7 53.2 252.4 147.8 113.9 55.9 76.3 46.6 57.4 42.1 56.0 90.0 10.7 640.8 19.7 26.7 45.5 46.9 59.3 23.3 9.9 213.3 158.1 33.6 21.7 49.0 ANXA4 ANX4 ENSG00000196975 "Annexin A4" P09525 2 69644425-69827112 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 569.9;pancreas: 356.8" "Cell type enhanced" "Detected in all" "Cholangiocytes: 2344.8;Ductal cells: 1469.8;Proximal enterocytes: 657.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 414.2;Hep G2: 456.9;RPTEC TERT1: 623.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005076, HPA007393, CAB017560" Enhanced Approved Cytosol NA NA 550000 "Cluster 24: B-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 1: Pancreatic cells - Digestion" Cytosol "CAB005076: AB_630869, CAB017560: AB_2227370, HPA007393: AB_1078168" "prognostic unfavorable (8.55e-4)" "unprognostic (3.37e-2)" "unprognostic (4.82e-2)" "unprognostic (9.03e-2)" "unprognostic (1.62e-3)" "unprognostic (1.66e-1)" "unprognostic (3.57e-1)" "unprognostic (3.21e-1)" "unprognostic (4.52e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (7.23e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.79e-1)" "unprognostic (8.85e-2)" "unprognostic (3.60e-2)" "unprognostic (3.97e-2)" 48.2 21.6 14.5 33.6 15.4 30.8 45.9 14.9 18.9 62.4 52.4 101.7 271.3 50.9 30.3 43.0 68.6 569.9 26.1 14.4 15.2 104.0 120.9 81.6 21.1 15.6 15.1 38.8 356.8 78.0 11.9 52.7 15.8 46.3 92.3 30.0 39.2 52.1 17.2 61.0 232.4 52.0 15.7 24.2 108.2 9.7 15.2 23.0 43.6 20.4 24.0 61.3 50.2 16.6 69.6 249.4 3.4 31.0 185.0 158.3 11.3 66.0 101.5 27.1 38.0 37.9 121.7 22.8 414.2 109.5 78.9 104.7 23.8 108.1 27.6 65.2 20.3 35.0 20.5 456.9 131.2 12.5 43.0 95.9 104.8 36.5 87.3 62.9 71.1 11.0 2.0 20.1 74.7 63.8 18.3 22.8 6.1 280.0 34.3 19.4 6.8 28.3 623.2 99.1 5.1 22.9 72.9 99.5 103.8 35.6 33.3 156.3 100.9 49.2 23.8 65.5 37.7 8.2 9.7 1.3 75.8 59.7 34.1 80.4 34.7 29.6 23.1 42.5 17.5 40.6 11.7 17.5 50.6 46.7 2.0 12.5 4.9 9.5 58.7 15.5 14.5 24.2 14.5 15.4 14.9 18.9 14.4 15.2 15.6 15.1 15.8 15.7 15.2 16.6 66.4 205.1 154.8 47.3 27.3 74.2 98.5 148.2 68.9 8.2 36.8 36.4 10.6 2344.8 139.4 84.6 6.2 86.4 27.2 315.1 221.1 1469.8 14.6 257.9 79.0 49.1 18.6 12.6 29.9 344.4 370.1 103.6 196.7 488.8 111.5 24.3 33.9 68.5 227.6 8.4 17.7 193.8 240.1 46.1 80.4 11.2 64.7 54.5 92.5 63.7 87.2 48.7 45.3 17.6 106.0 245.7 268.6 92.2 6.9 55.6 657.1 400.4 230.2 59.9 6.6 27.6 64.6 15.8 3.7 61.3 79.6 439.6 32.5 19.1 174.1 96.9 GMCL1 "BTBD13, FLJ13057, GCL1, SPATA29" ENSG00000087338 "Germ cell-less 1, spermatogenesis associated" Q96IK5 2 69829660-69881384 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 264.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 93.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039579 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "HPA039579: AB_10805480" "unprognostic (1.89e-2)" "unprognostic (4.95e-2)" "unprognostic (2.53e-2)" "unprognostic (1.79e-2)" "unprognostic (4.09e-2)" "unprognostic (1.96e-1)" "unprognostic (5.20e-2)" "unprognostic (2.60e-3)" "unprognostic (1.27e-1)" "unprognostic (8.80e-2)" "unprognostic (3.04e-1)" "unprognostic (5.94e-2)" "unprognostic (2.48e-3)" "unprognostic (1.10e-2)" "unprognostic (1.68e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" 9.4 6.5 4.4 8.1 4.8 13.6 10.6 5.3 6.7 8.6 11.6 10.7 15.9 7.7 8.8 8.2 7.9 8.5 4.8 5.2 4.4 11.5 10.7 7.7 12.0 4.4 4.7 8.5 9.1 19.1 6.5 9.3 4.3 11.1 12.2 6.1 9.4 8.7 4.1 8.8 13.1 6.4 4.6 9.1 8.6 16.3 4.5 18.5 9.2 5.4 12.2 8.3 6.3 5.3 14.7 10.3 17.2 18.4 15.0 13.1 18.4 12.1 8.0 8.1 13.7 9.9 13.5 30.7 9.7 8.0 9.5 14.2 20.3 10.5 14.1 14.2 21.2 48.0 11.3 22.8 9.9 36.1 32.4 7.2 11.3 6.4 14.9 10.5 14.5 23.2 19.5 21.8 12.9 12.6 37.1 33.7 18.4 24.9 9.6 26.1 22.6 23.6 11.9 22.2 27.0 22.5 13.2 19.1 14.8 13.4 12.6 22.2 9.0 12.4 15.5 19.4 14.7 22.1 28.6 18.9 12.8 29.5 13.0 93.5 8.0 40.1 11.1 6.3 19.1 8.8 10.9 13.7 7.5 8.3 15.6 15.5 26.8 26.8 10.3 7.9 15.5 9.4 4.4 4.8 5.3 6.7 5.2 4.4 4.4 4.7 4.3 4.6 4.5 5.3 17.9 28.9 27.4 22.9 25.9 26.8 21.4 19.5 27.3 22.5 28.3 20.4 7.6 74.4 22.0 18.4 27.1 38.3 42.5 40.0 41.1 36.1 264.8 26.7 21.8 19.5 23.4 29.0 68.1 17.5 51.9 19.4 16.3 18.4 22.2 24.2 26.4 25.4 15.9 21.9 63.8 37.0 44.7 23.8 13.1 50.8 15.8 15.0 16.0 11.2 22.8 44.2 50.4 42.7 45.6 15.2 21.7 22.6 28.2 33.0 42.1 23.2 38.4 37.0 13.1 26.0 21.1 44.2 45.1 38.4 27.7 81.5 36.7 17.5 30.6 25.7 SNRNP27 "RY1, U4/U6.U5-27K" ENSG00000124380 "Small nuclear ribonucleoprotein U4/U6.U5 subunit 27" Q8WVK2 2 69893956-69905575 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034541 Approved Approved Nucleoplasm NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA034541: AB_10602408" "unprognostic (2.24e-1)" "unprognostic (6.11e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.89e-2)" "unprognostic (1.28e-2)" "unprognostic (1.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.61e-2)" "unprognostic (1.30e-2)" "unprognostic (1.26e-1)" "unprognostic (3.18e-1)" "unprognostic (4.35e-3)" "unprognostic (9.12e-2)" "unprognostic (2.16e-1)" "unprognostic (2.26e-1)" "unprognostic (1.86e-1)" 31.0 33.4 25.3 23.9 26.6 43.2 26.1 28.0 40.1 19.9 21.5 18.2 17.4 23.5 24.3 19.8 19.1 21.5 39.5 27.3 27.6 23.5 24.6 19.2 32.8 23.6 26.5 21.7 18.5 32.1 16.3 30.3 25.2 23.7 20.9 25.3 21.8 19.3 62.2 19.5 20.4 24.0 26.0 22.6 18.4 14.2 25.3 31.7 26.9 71.8 27.7 24.8 13.4 30.7 27.9 16.2 52.0 31.4 44.7 49.0 41.7 38.5 45.4 54.2 42.9 34.0 31.3 29.6 30.5 31.5 56.0 15.3 34.9 16.1 67.3 33.3 34.1 34.2 14.4 42.2 40.1 43.6 57.9 36.0 38.6 35.4 30.4 44.4 42.0 41.6 49.0 46.6 72.1 15.6 59.4 73.9 38.1 30.1 16.2 46.0 42.9 31.1 60.0 18.5 53.0 41.9 28.7 30.8 42.7 39.0 28.1 35.4 24.6 37.1 51.3 53.7 58.5 28.5 29.9 45.7 33.2 52.4 71.7 43.2 25.1 38.9 23.6 23.5 25.2 37.9 25.7 23.4 22.2 32.2 27.8 27.7 13.7 32.2 25.2 40.8 30.3 25.1 25.3 26.6 28.0 40.1 27.3 27.6 23.6 26.5 25.2 26.0 25.3 30.7 45.3 54.5 39.3 6.5 57.1 49.1 40.5 47.0 44.9 31.6 53.0 32.4 60.7 47.1 36.1 62.5 14.6 49.2 69.9 40.5 74.3 57.7 37.4 37.0 44.8 42.0 38.9 82.7 14.1 55.1 70.1 50.5 18.8 44.6 60.0 24.5 56.4 78.8 57.4 23.5 11.6 52.7 22.4 57.7 46.6 12.4 51.3 48.5 37.4 8.4 50.6 41.8 68.0 4.0 7.6 70.4 42.8 57.9 60.2 34.3 33.9 63.8 47.2 31.2 39.5 32.4 45.2 76.2 61.7 33.9 46.0 52.5 51.7 20.3 37.5 37.7 MXD1 "bHLHc58, MAD, MAD1" ENSG00000059728 "MAX dimerization protein 1" Q05195 2 69897688-69942945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 173.4;esophagus: 130.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 507.0;Langerhans cells: 224.8;Paneth cells: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 496.3" "Lineage enriched" "Detected in all" 49 "granulocytes: 496.3" "Cell line enhanced" "Detected in many" "hTERT-HME1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001599 Enhanced Uncertain Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" Cytosol "HPA001599: AB_1079434" "unprognostic (1.59e-1)" "unprognostic (5.11e-2)" "unprognostic (1.63e-2)" "prognostic unfavorable (8.14e-6)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (4.36e-2)" "unprognostic (8.73e-3)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (8.50e-4)" "unprognostic (8.72e-2)" "unprognostic (3.24e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-1)" "unprognostic (1.56e-3)" "unprognostic (1.77e-2)" 13.5 3.6 6.2 40.4 6.9 173.4 7.0 10.0 15.8 35.2 6.4 30.3 28.8 5.4 1.9 130.0 8.1 9.4 8.3 6.5 7.8 6.8 11.3 36.5 3.9 7.1 6.3 6.1 4.6 6.8 6.7 10.9 8.1 5.5 28.9 15.6 17.4 2.0 6.0 12.8 43.7 9.1 5.4 32.8 16.9 6.3 10.7 13.9 7.5 6.5 15.1 17.4 50.6 10.5 5.0 2.1 3.0 2.2 6.5 3.2 11.2 5.5 3.1 2.6 1.9 6.8 3.8 2.8 2.8 2.1 2.5 17.3 5.8 10.7 2.7 1.6 6.9 5.9 6.6 7.0 21.9 7.3 5.7 3.7 17.8 5.9 27.0 3.2 3.4 2.8 10.4 10.9 1.6 4.0 3.4 14.1 0.8 7.3 3.5 1.6 3.1 7.1 3.4 5.8 9.8 4.1 7.3 9.3 3.9 3.4 1.4 4.1 13.2 3.7 1.0 4.1 5.2 7.5 13.7 1.1 3.8 12.5 1.4 124.0 10.2 105.7 2.3 6.4 2.5 1.1 1.6 1.7 5.2 1.3 1.8 1.9 496.3 2.8 5.5 1.6 1.5 4.5 6.2 6.9 10.0 15.8 6.5 7.8 7.1 6.3 8.1 5.4 10.7 10.5 18.0 38.5 23.7 16.0 25.4 25.7 31.6 61.8 21.6 29.8 51.6 29.3 6.9 10.0 44.7 1.8 54.2 10.1 46.2 507.0 7.9 12.9 17.0 34.3 17.5 12.0 97.5 17.7 23.6 16.5 8.0 17.9 110.1 81.6 27.3 3.0 5.7 6.8 28.6 10.1 20.2 155.5 71.2 56.5 224.8 17.8 4.7 190.8 16.0 11.2 40.7 62.1 18.6 20.1 21.7 70.1 369.6 2.6 33.1 43.3 178.8 6.9 24.2 21.7 0.0 14.7 18.3 19.9 2.7 88.2 56.4 105.9 30.3 5.2 65.9 126.7 ASPRV1 "FLJ25084, SASPase, Taps" ENSG00000244617 "Aspartic peptidase retroviral like 1" Q53RT3 2 69960089-69962265 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Aspartyl protease, Hydrolase, Protease" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "skin 1: 424.0" "Cell type enhanced" "Detected in some" "NK-cells: 3.1;Oligodendrocytes: 4.2;Spermatogonia: 3.3;Suprabasal keratinocytes: 10.7" "Group enriched" "Detected in many" 8 "head and neck cancer: 23.1;melanoma: 35.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 8.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 8.7" "Cell line enhanced" "Detected in some" "NB-4: 2.9;REH: 4.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA034809, HPA034810" Enhanced Approved Cytosol NA NA 150000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 61: Skin - Cornification" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "HPA034809: AB_2674343, HPA034810: AB_10601456" "unprognostic (4.75e-4)" "unprognostic (1.90e-3)" "unprognostic (2.34e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-1)" "unprognostic (1.17e-2)" "unprognostic (1.93e-3)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (4.19e-3)" "unprognostic (1.27e-1)" "unprognostic (4.01e-2)" "unprognostic (3.00e-1)" "unprognostic (1.74e-1)" "unprognostic (4.84e-2)" "unprognostic (2.43e-2)" 2.6 2.1 5.8 0.9 7.3 0.9 17.1 6.1 6.6 3.1 3.0 1.7 1.6 2.5 2.6 0.9 2.3 1.1 1.8 5.3 6.0 2.2 1.9 1.7 1.0 7.2 6.7 4.8 0.7 0.2 4.0 0.9 6.5 2.2 0.6 1.5 1.3 1.3 4.4 424.0 1.7 1.2 6.0 3.9 1.2 3.6 6.5 2.1 1.3 2.1 1.0 1.5 4.5 9.3 0.0 0.3 0.9 1.9 1.2 0.4 0.2 0.2 0.4 0.2 0.1 0.6 0.0 0.7 0.1 0.2 0.2 0.2 0.8 0.1 0.2 1.3 2.5 1.5 0.2 0.6 0.4 1.3 1.0 0.5 0.4 0.2 0.4 0.3 0.2 1.6 0.5 1.9 0.2 0.3 1.1 2.9 1.0 0.2 0.2 4.9 0.5 0.3 0.0 0.0 1.0 0.2 0.1 0.7 0.8 0.2 0.0 0.5 0.1 0.0 0.9 0.0 0.2 2.0 1.3 1.4 0.1 0.9 1.0 0.0 0.1 1.5 0.5 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.1 0.4 8.7 0.3 0.0 0.8 0.7 0.4 5.8 7.3 6.1 6.6 5.3 6.0 7.2 6.7 6.5 6.0 6.5 9.3 1.1 0.0 0.0 1.3 0.0 0.4 0.1 0.2 0.0 1.1 0.5 0.9 2.6 0.0 0.1 1.8 0.0 0.3 0.1 0.5 0.0 0.1 0.1 0.4 0.5 0.8 0.0 0.0 1.0 0.2 0.0 0.7 0.0 0.4 0.0 1.1 1.4 0.1 0.2 0.0 1.5 0.9 0.0 0.3 0.6 0.5 0.9 0.3 0.0 1.0 0.2 1.2 3.1 1.5 4.2 0.3 0.0 0.7 0.1 0.2 1.1 0.9 0.2 1.6 0.0 0.7 1.1 1.4 3.3 0.0 10.7 0.4 0.2 0.5 0.2 0.1 PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" No No 1600000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Cytoplasmic bodies" "CAB037113: AB_1840915, HPA043803: AB_2678676, HPA068497: AB_2685996" "unprognostic (1.63e-1)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (7.08e-2)" "unprognostic (5.37e-1)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (9.94e-3)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (3.85e-2)" "unprognostic (9.25e-2)" "unprognostic (1.22e-1)" "unprognostic (5.90e-2)" 278.3 276.3 145.5 199.8 155.0 390.0 240.4 168.5 203.5 209.3 159.1 259.9 172.8 253.9 142.6 278.4 193.8 134.9 223.2 142.1 155.6 218.1 304.3 233.6 227.1 163.7 146.9 186.0 249.9 174.6 140.2 194.8 159.2 143.9 125.8 90.5 185.0 139.5 782.3 216.6 203.1 172.4 163.8 241.3 214.5 95.2 150.4 301.0 170.8 308.3 209.6 233.8 206.0 190.9 384.9 387.5 327.1 257.5 345.1 262.4 525.9 280.5 257.2 272.0 227.0 453.0 250.6 522.9 140.9 320.7 293.7 334.7 388.4 408.6 276.5 376.2 299.9 419.2 219.5 701.3 388.0 350.8 385.8 230.3 261.6 224.5 310.5 203.4 350.7 138.9 437.2 375.6 346.2 475.7 454.7 524.7 331.5 361.1 253.2 362.9 358.0 527.1 375.5 389.6 309.7 249.1 230.3 465.8 342.1 229.8 277.6 314.2 325.1 253.5 317.6 217.6 359.4 495.7 551.2 531.7 268.6 480.4 319.5 42.6 89.7 141.5 80.3 92.5 73.8 41.1 62.1 69.3 82.9 36.4 62.8 71.2 138.2 95.4 80.5 58.9 81.7 100.5 145.5 155.0 168.5 203.5 142.1 155.6 163.7 146.9 159.2 163.8 150.4 190.9 241.0 153.8 132.7 27.4 312.7 484.0 296.0 192.1 196.9 64.9 270.8 212.6 0.6 208.8 134.5 196.8 22.9 372.4 208.7 401.7 272.0 196.0 34.4 187.6 220.8 242.8 178.6 485.3 19.1 199.2 470.1 196.9 227.9 284.8 114.2 129.6 227.0 392.7 385.7 58.9 18.0 239.8 138.4 509.2 795.9 34.4 186.1 382.4 300.6 30.0 422.9 122.3 347.1 14.1 49.1 211.7 311.7 186.5 357.1 278.5 338.4 481.0 128.6 56.1 170.9 222.9 241.9 131.0 65.5 267.0 545.8 703.4 291.2 148.4 232.9 366.6 C2orf42 FLJ20558 ENSG00000115998 "Chromosome 2 open reading frame 42" Q9NWW7 2 70149885-70248615 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0" "Cell type enhanced" "Detected in many" "Early spermatids: 262.9;Late spermatids: 98.5;Spermatocytes: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031840, HPA031841, HPA031842" Enhanced Enhanced Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA031840: AB_2674066, HPA031841: AB_10601124, HPA031842: AB_2674068" "unprognostic (8.49e-2)" "unprognostic (2.09e-1)" "unprognostic (2.52e-1)" "unprognostic (1.03e-1)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (1.92e-1)" "unprognostic (2.20e-3)" "unprognostic (2.26e-1)" "unprognostic (3.73e-1)" "prognostic favorable (5.94e-5)" "unprognostic (4.66e-2)" "unprognostic (9.41e-2)" "unprognostic (2.11e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-1)" "unprognostic (2.49e-3)" 6.5 7.3 11.2 5.9 12.7 4.8 6.4 16.3 12.5 7.8 10.6 6.5 4.4 8.5 10.9 6.4 11.2 7.5 5.8 10.4 11.7 8.4 15.4 6.0 12.4 10.8 11.5 10.2 6.7 11.5 7.8 8.0 11.5 6.7 5.2 7.5 6.4 7.2 6.7 6.7 6.3 7.5 10.9 8.8 6.1 59.0 11.9 10.1 8.2 8.4 11.6 8.2 6.2 16.1 5.9 9.6 8.9 8.1 17.9 10.4 10.1 13.9 9.4 11.0 9.4 7.8 5.1 7.5 7.9 8.3 18.0 8.0 9.4 7.9 12.2 13.1 8.3 8.8 6.8 7.7 15.9 7.3 8.6 12.5 14.1 10.5 13.3 12.0 10.8 9.4 7.5 27.6 14.7 4.6 9.4 10.7 6.4 9.9 10.6 8.8 12.1 13.8 9.0 6.8 7.4 7.5 7.5 11.6 14.4 6.2 5.2 8.9 8.5 9.8 6.7 9.1 11.4 15.1 16.2 7.5 7.6 11.8 8.9 2.3 7.7 9.9 12.1 7.2 15.5 14.2 12.2 14.7 7.9 13.0 13.9 14.9 8.3 21.9 7.8 7.0 15.5 10.9 11.2 12.7 16.3 12.5 10.4 11.7 10.8 11.5 11.5 10.9 11.9 16.1 4.0 0.0 2.2 7.8 8.9 2.5 3.4 3.7 5.7 5.8 4.0 5.0 2.8 1.5 2.8 5.5 0.0 8.8 6.1 4.2 7.9 4.5 262.9 3.8 3.3 3.6 1.2 4.0 9.2 2.4 4.0 4.4 3.6 2.8 2.5 5.0 6.4 6.9 4.3 0.0 8.9 2.1 2.0 4.7 3.1 98.5 7.5 3.6 3.6 2.8 3.1 9.0 9.2 8.0 12.3 2.0 3.1 7.9 8.4 2.9 3.3 6.4 6.6 4.1 0.0 4.2 3.8 63.1 12.0 3.5 4.3 9.6 5.3 4.3 2.5 2.0 TIA1 TIA-1 ENSG00000116001 "TIA1 cytotoxic granule associated RNA binding protein" P31483 2 70209444-70248660 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 172.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056961 Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "HPA056961: AB_2683289" "unprognostic (1.04e-1)" "unprognostic (1.74e-1)" "unprognostic (3.68e-2)" "unprognostic (1.07e-1)" "unprognostic (7.64e-3)" "unprognostic (2.51e-3)" "unprognostic (3.37e-3)" "prognostic favorable (6.79e-5)" "unprognostic (5.09e-3)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (8.05e-7)" "unprognostic (4.00e-1)" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "prognostic favorable (1.02e-5)" 27.3 34.4 20.0 34.3 23.5 28.0 47.5 27.6 29.2 63.6 25.0 42.3 35.6 68.5 70.2 26.1 50.5 36.6 27.3 20.0 21.4 46.0 33.1 32.8 49.6 22.4 21.1 73.8 41.2 29.7 49.3 36.7 22.7 43.5 39.8 68.0 42.2 35.1 24.6 40.3 45.8 41.0 21.4 51.4 37.0 19.7 21.2 67.6 47.6 25.7 35.8 36.8 39.9 29.7 21.0 22.9 117.4 66.1 32.7 55.1 56.6 36.6 25.8 34.8 34.4 31.0 31.7 47.1 30.7 27.3 20.2 33.8 57.5 20.0 48.9 44.2 25.1 48.9 43.2 74.4 26.1 49.5 26.6 41.2 29.0 20.0 21.9 82.3 65.1 37.5 38.4 41.9 49.4 17.9 91.9 78.0 95.8 30.0 27.0 110.5 63.8 48.0 53.3 40.7 71.0 60.6 43.2 50.8 36.0 60.5 30.4 36.2 53.6 42.5 44.3 20.1 36.6 34.9 36.9 86.7 24.9 62.1 57.6 13.5 5.9 8.4 5.6 5.0 5.4 7.1 5.5 5.8 8.8 5.2 5.0 5.6 2.3 8.2 3.1 4.5 7.6 3.9 20.0 23.5 27.6 29.2 20.0 21.4 22.4 21.1 22.7 21.4 21.2 29.7 45.8 83.3 63.4 91.7 44.7 25.4 31.2 25.1 38.1 52.7 46.9 40.6 30.8 28.6 54.8 20.2 47.9 31.3 40.3 23.0 0.0 31.0 21.0 31.9 70.6 40.1 52.6 42.9 95.0 27.1 34.6 40.8 36.2 34.2 55.7 106.7 33.2 30.6 21.1 35.3 94.5 31.7 32.6 29.4 28.7 9.3 36.1 32.4 16.0 57.1 44.0 31.4 28.8 152.3 172.0 30.1 23.6 35.7 38.2 32.5 24.8 14.0 58.8 51.8 26.3 25.4 45.7 30.0 19.3 26.0 24.0 24.8 43.5 44.3 31.9 29.7 PCYOX1 "KIAA0908, PCL1" ENSG00000116005 "Prenylcysteine oxidase 1" Q9UHG3 2 70257386-70281185 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 599.4;Hepatocytes: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 313.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035193 Approved "Intracellular and membrane" NA NA 510000000 "Cluster 44: Non-specific - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA035193: AB_10602017" "unprognostic (1.09e-1)" "unprognostic (1.72e-2)" "unprognostic (7.91e-2)" "unprognostic (1.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.05e-1)" "unprognostic (6.87e-2)" "unprognostic (6.28e-2)" "unprognostic (1.14e-1)" "unprognostic (1.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.26e-2)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" 78.5 33.5 15.4 12.7 15.7 3.7 34.4 12.1 18.4 56.5 29.3 26.9 24.9 39.9 33.6 38.8 35.6 31.7 37.7 14.7 27.8 92.6 103.5 56.2 14.6 16.5 22.0 39.6 20.6 66.0 17.9 29.0 24.9 44.3 23.6 30.7 70.1 46.6 92.1 33.0 24.5 40.8 14.6 15.6 22.1 14.2 28.4 11.1 60.0 50.4 14.2 25.7 25.2 13.2 38.8 54.9 43.2 48.6 313.2 160.0 37.9 64.8 59.4 35.4 26.5 86.5 33.6 4.0 27.3 89.2 58.2 62.2 31.7 50.2 40.5 22.1 26.9 14.9 41.0 75.7 31.4 14.1 12.7 154.9 54.1 47.4 13.3 93.9 42.6 14.2 27.0 27.8 50.7 23.6 10.7 22.8 26.1 55.9 23.1 19.6 90.2 34.5 50.1 42.8 11.3 24.1 97.8 47.7 45.5 61.0 39.1 18.2 53.4 59.2 32.7 52.9 34.2 22.9 55.1 5.1 71.3 19.3 22.1 16.3 6.5 6.8 8.3 5.4 10.4 3.7 8.0 6.7 5.9 2.8 10.8 9.2 4.1 6.1 6.0 7.4 7.8 6.5 15.4 15.7 12.1 18.4 14.7 27.8 16.5 22.0 24.9 14.6 28.4 13.2 37.3 599.4 77.5 16.0 12.2 21.3 23.1 43.9 29.6 48.7 46.0 31.8 81.1 40.0 49.9 53.3 43.8 43.4 12.1 30.7 7.9 26.7 1.7 18.4 65.9 33.4 8.5 12.0 24.7 10.2 36.0 81.9 22.4 36.2 10.1 20.9 39.7 187.8 22.1 57.2 36.8 21.0 36.7 17.4 9.2 3.9 89.2 14.3 24.9 23.4 8.6 90.3 11.3 21.6 18.0 13.9 21.0 120.7 26.2 27.0 47.7 69.0 25.0 36.9 72.3 65.5 63.7 14.7 32.2 40.8 28.3 22.0 14.5 56.2 26.5 18.4 SNRPG Sm-G ENSG00000143977 "Small nuclear ribonucleoprotein polypeptide G" P62308 2 70281362-70293740 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA064152, HPA067814" Supported Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA064152: AB_2685199, HPA067814: AB_2685903" "unprognostic (6.42e-2)" "unprognostic (7.89e-2)" "unprognostic (6.10e-2)" "unprognostic (5.42e-2)" "unprognostic (1.29e-1)" "unprognostic (1.11e-3)" "unprognostic (1.75e-3)" "unprognostic (2.28e-2)" "unprognostic (3.60e-3)" "unprognostic (6.19e-2)" "unprognostic (1.00e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (1.08e-6)" "unprognostic (4.37e-2)" "unprognostic (1.33e-1)" "unprognostic (8.96e-2)" "unprognostic (1.41e-2)" 66.9 92.0 55.9 85.9 58.0 118.0 85.1 58.4 85.7 50.4 60.2 87.9 62.1 55.2 103.0 95.5 45.6 40.5 102.2 55.3 58.3 97.1 95.5 59.8 100.7 58.9 58.0 49.2 53.1 69.5 60.4 83.8 59.5 53.7 80.3 92.7 59.2 46.0 88.3 43.5 63.2 51.6 59.1 76.6 61.1 60.1 58.4 139.9 61.2 83.8 96.9 91.4 56.3 63.1 398.0 414.3 412.2 240.0 146.5 157.1 369.0 255.4 230.5 332.8 307.2 718.7 258.1 355.1 180.6 202.2 404.9 253.9 415.1 355.7 356.7 333.2 404.5 474.0 256.6 875.4 194.0 602.3 313.6 140.2 198.1 312.8 308.8 135.0 341.5 301.1 645.3 254.8 266.9 479.0 541.5 961.8 430.4 489.9 340.2 350.4 507.9 419.0 483.9 367.1 238.1 204.4 235.9 201.1 295.8 250.7 202.1 470.1 232.9 235.3 440.2 246.3 520.4 188.1 228.3 731.8 211.1 510.0 260.9 163.1 168.5 181.1 144.2 219.2 147.4 209.1 193.4 168.8 202.5 166.0 157.8 188.9 88.1 135.8 222.4 273.0 230.1 264.8 55.9 58.0 58.4 85.7 55.3 58.3 58.9 58.0 59.5 59.1 58.4 63.1 191.7 201.9 198.9 7.2 237.0 299.1 340.3 625.6 143.4 88.8 192.3 239.1 145.7 178.7 314.8 202.3 33.3 655.3 175.7 249.1 534.1 389.6 51.0 253.2 184.7 209.1 186.6 319.4 7.4 391.5 818.7 173.3 119.3 188.4 213.3 140.7 175.3 391.8 390.8 65.6 8.7 301.5 370.2 186.6 270.8 45.4 175.8 194.0 224.1 5.6 329.1 446.1 208.1 4.5 13.8 434.1 271.6 159.1 251.9 366.1 226.5 676.1 401.8 91.4 184.1 181.3 244.4 340.7 367.4 236.6 318.2 521.5 220.2 125.9 324.1 375.1 FAM136A FLJ14668 ENSG00000035141 "Family with sequence similarity 136 member A" Q96C01 2 70295975-70302090 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030103, HPA030104" Enhanced Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" Mitochondria "HPA030103: AB_10600194, HPA030104: AB_10600534" "unprognostic (2.81e-1)" "unprognostic (5.76e-2)" "unprognostic (9.16e-2)" "unprognostic (3.69e-2)" "unprognostic (5.53e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (1.28e-2)" "unprognostic (5.91e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (1.33e-6)" "unprognostic (4.95e-3)" "unprognostic (3.03e-1)" "unprognostic (4.03e-1)" "unprognostic (2.00e-3)" 10.7 12.2 16.0 17.8 16.4 20.4 16.8 16.4 19.4 15.2 16.1 25.9 26.1 10.0 14.6 19.2 14.3 9.7 21.5 16.0 17.8 20.1 32.5 10.5 17.5 17.0 17.0 10.6 31.4 20.6 10.3 18.0 17.9 15.8 27.1 16.4 27.1 14.1 24.5 14.7 21.6 14.0 15.8 13.6 19.6 8.9 17.9 17.7 20.6 22.2 21.4 17.8 10.5 15.5 94.8 83.4 51.5 72.4 26.5 39.1 78.4 50.2 47.7 67.8 46.8 222.0 53.3 64.9 44.5 43.6 58.9 42.5 106.8 40.0 69.2 67.1 121.3 99.7 62.1 138.8 38.1 166.5 62.7 27.0 27.3 63.9 54.0 36.3 73.8 93.0 161.1 51.0 51.0 138.0 107.6 143.9 129.2 127.7 88.7 71.2 96.2 107.1 104.9 65.4 119.7 52.3 37.7 90.6 76.1 47.3 37.6 47.9 44.9 28.9 85.1 44.7 96.2 42.3 70.0 75.2 72.0 93.2 50.1 35.8 27.9 21.0 21.3 39.8 31.9 37.0 23.6 25.9 37.8 33.2 27.3 27.6 2.6 53.4 27.9 24.8 20.5 29.6 16.0 16.4 16.4 19.4 16.0 17.8 17.0 17.0 17.9 15.8 17.9 15.5 16.7 41.7 31.6 8.8 49.5 28.0 35.4 41.3 35.3 26.3 46.6 46.1 54.7 11.5 38.9 33.1 25.0 89.5 46.0 52.3 70.5 71.8 1.3 39.3 28.3 20.1 32.9 50.5 8.6 99.1 107.5 31.9 40.8 47.1 27.9 46.1 18.9 59.3 69.8 8.4 9.4 61.2 44.7 22.4 29.2 3.6 13.4 31.9 28.4 3.7 42.0 29.1 49.4 6.0 3.6 95.0 58.1 18.4 88.6 54.8 69.7 73.5 31.8 26.7 13.1 19.8 32.5 14.0 53.8 49.8 41.9 29.6 36.8 49.2 66.7 45.7 TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 59.3;Pancreatic endocrine cells: 74.5;Urothelial cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.3;eosinophil: 23.8;neutrophil: 23.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 23.8" "Cell line enhanced" "Detected in many" "A-431: 72.5;CAPAN-2: 82.5;HBEC3-KT: 72.3;OE19: 54.6;RPTEC TERT1: 72.6;U-87 MG: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" No No 57900 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" 2.2 0.5 9.2 5.0 16.8 1.6 6.9 15.0 12.2 6.1 5.2 10.7 8.5 1.3 2.9 25.5 6.1 14.1 0.7 10.4 11.7 13.4 4.5 3.9 4.1 21.0 15.8 0.1 7.5 3.0 0.5 1.9 18.5 2.4 7.9 7.4 6.4 1.2 0.1 12.2 10.0 1.4 16.6 5.8 8.5 2.5 13.2 1.0 8.1 0.3 9.0 10.0 12.8 27.3 72.5 11.3 0.1 0.2 0.0 0.0 0.0 11.0 0.0 0.3 0.1 0.2 82.5 0.0 43.2 0.4 11.2 37.1 0.6 72.3 0.1 0.1 1.6 0.0 1.8 6.0 0.0 0.9 0.1 0.0 29.1 0.1 27.8 3.4 0.0 5.6 0.0 0.4 0.0 2.6 0.1 1.4 1.1 54.6 22.9 0.0 0.5 19.8 72.6 27.2 0.6 0.1 5.8 0.0 0.1 0.2 9.8 0.7 0.6 0.3 4.9 0.1 15.7 0.4 0.6 0.1 69.0 2.4 25.6 11.3 0.8 23.8 1.7 0.2 4.4 0.0 1.0 1.0 1.0 0.0 0.5 0.4 23.8 0.3 0.0 0.0 0.0 0.7 9.2 16.8 15.0 12.2 10.4 11.7 21.0 15.8 18.5 16.6 13.2 27.3 0.4 6.4 2.7 0.3 0.2 16.2 12.3 16.9 10.8 1.4 9.8 12.1 2.3 24.3 21.8 25.8 0.0 0.0 2.2 19.8 1.9 37.3 21.3 8.1 0.7 1.7 1.2 0.0 0.8 10.0 0.0 0.6 13.7 10.5 5.7 0.0 0.0 3.0 3.9 0.0 3.6 6.2 12.2 3.2 2.4 1.9 0.3 4.1 0.0 6.5 18.2 7.9 2.1 59.3 36.1 74.5 9.0 0.0 0.7 16.8 21.1 6.6 20.4 0.7 0.0 0.1 1.1 0.6 0.2 12.2 24.9 0.0 1.9 0.0 5.6 63.6 ADD2 ADDB ENSG00000075340 "Adducin 2" P35612 2 70607618-70768225 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.5;brain: 52.8" "Cell type enhanced" "Detected in many" "Early spermatids: 31.7;Erythroid cells: 74.1;Excitatory neurons: 70.1;Horizontal cells: 139.7;Inhibitory neurons: 51.8;Late spermatids: 62.4" "Group enriched" "Detected in many" 5 "glioma: 5.2;testis cancer: 11.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 33.9;JURKAT: 33.1;K-562: 46.5;NTERA-2: 86.7;RPMI-8226: 41.7;SCLC-21H: 42.8;U-251 MG: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009796, HPA034509, HPA034510" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009796: AB_2223572, HPA034509: AB_2674201, HPA034510: AB_2674202" "unprognostic (3.58e-2)" "unprognostic (2.68e-4)" "unprognostic (3.83e-2)" "unprognostic (3.01e-4)" "unprognostic (1.94e-1)" "unprognostic (2.25e-3)" "unprognostic (1.35e-1)" "unprognostic (3.26e-1)" "unprognostic (3.49e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (8.93e-2)" "unprognostic (4.47e-7)" "unprognostic (2.81e-4)" "unprognostic (1.77e-1)" "unprognostic (1.71e-3)" "unprognostic (1.31e-3)" 1.8 1.7 19.5 1.9 21.0 66.5 0.9 14.6 52.8 0.7 0.0 0.9 0.1 0.5 0.3 1.4 0.7 0.3 0.9 18.7 10.8 0.4 0.2 0.9 2.5 14.0 0.2 0.2 1.7 0.2 4.0 0.7 9.5 0.5 0.3 16.0 0.2 0.2 0.8 0.3 0.9 1.0 0.0 1.2 0.3 2.8 0.9 0.7 1.4 1.0 2.2 0.5 0.6 9.6 17.6 20.5 0.8 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 2.7 12.3 0.0 33.9 0.0 0.0 0.1 20.1 1.7 0.2 0.0 0.0 4.7 0.1 0.0 0.0 0.0 0.0 8.0 0.0 33.1 46.5 0.0 0.0 0.1 0.2 1.6 86.7 0.0 0.4 0.0 0.5 41.7 5.7 0.0 42.8 19.3 21.6 0.1 0.1 9.4 0.1 10.7 0.8 0.2 0.9 0.0 47.1 14.1 17.0 0.0 0.7 7.1 7.9 0.0 0.0 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.0 1.7 0.8 0.4 0.0 0.0 2.3 0.0 0.0 0.3 19.5 21.0 14.6 52.8 18.7 10.8 14.0 0.2 9.5 0.0 0.9 9.6 2.8 0.0 0.5 1.0 4.2 0.1 0.3 0.0 0.0 23.3 0.2 0.0 2.5 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.1 31.7 0.1 0.2 3.9 0.0 74.1 70.1 1.1 0.2 1.0 1.1 0.1 0.0 0.0 2.9 0.0 0.2 139.7 51.8 0.0 0.0 1.0 0.4 62.4 0.9 0.6 1.8 2.8 0.8 0.8 0.0 17.6 1.8 0.3 0.0 0.7 0.1 0.6 0.0 0.0 0.0 8.7 0.0 0.6 0.3 3.5 6.8 0.0 0.1 0.3 0.5 1.5 0.0 1.3 FIGLA bHLHc8 ENSG00000183733 "Folliculogenesis specific bHLH transcription factor" Q6QHK4 2 70777310-70790643 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "retina: 1.1" "Group enriched" "Detected in some" 17 "Early spermatids: 1.9;Late spermatids: 6.4;Spermatogonia: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA071241 Supported NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 31: Spermatids - Spermatogenesis" "HPA071241: " "unprognostic (1.82e-1)" "unprognostic (4.04e-1)" "unprognostic (1.73e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Horizontal cells: 5.0;Macrophages: 4.5;monocytes: 4.0;Rod photoreceptor cells: 6.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cell line enhanced" "Detected in single" "AN3-CA: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA056101: " "unprognostic (8.14e-3)" "unprognostic (3.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (4.91e-2)" "unprognostic (5.41e-2)" "unprognostic (3.66e-2)" "unprognostic (2.07e-2)" "unprognostic (9.29e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-2)" "unprognostic (9.59e-2)" "unprognostic (2.44e-1)" 1.5 0.0 0.1 0.6 0.0 0.0 1.1 0.1 0.2 2.7 0.1 0.7 1.6 1.6 0.8 0.7 1.4 1.0 0.7 0.1 0.1 0.6 0.7 0.9 1.2 0.0 0.0 0.6 0.3 0.0 0.6 0.1 0.1 1.5 0.8 17.2 1.7 0.9 1.0 1.3 4.5 1.2 0.0 3.4 0.6 1.0 0.1 0.2 0.3 0.6 0.8 0.7 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.5 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.2 0.3 0.3 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.1 0.0 0.0 1.0 2.3 1.4 0.0 4.5 0.0 0.0 4.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 87.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.0;Langerhans cells: 9.7;Macrophages: 7.6;Melanocytes: 5.4;Suprabasal keratinocytes: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cell line enriched" "Detected in some" 4 "AN3-CA: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Cytosol "CAB002222: AB_563850, HPA011216: AB_1078453" "unprognostic (1.45e-2)" "unprognostic (8.28e-3)" "unprognostic (9.34e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-3)" "unprognostic (1.05e-1)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "unprognostic (1.63e-1)" "unprognostic (7.92e-4)" "unprognostic (2.13e-2)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (2.46e-2)" 0.4 0.1 0.0 0.3 0.0 0.0 3.2 0.0 0.0 1.6 0.1 1.2 3.7 0.8 0.4 17.8 0.9 2.0 0.2 0.0 0.0 0.1 0.7 1.6 0.9 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 2.4 2.7 5.5 1.1 0.8 0.8 87.7 4.9 0.7 0.0 3.7 1.4 0.5 0.0 3.4 0.1 0.3 4.8 1.4 1.7 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 1.6 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.6 4.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.2 0.0 7.6 5.4 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.0 VAX2 DRES93 ENSG00000116035 "Ventral anterior homeobox 2" Q9UIW0 2 70900576-70965373 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.4;retina: 11.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 9.5;Cone photoreceptor cells: 16.7;Horizontal cells: 11.8;Muller glia cells: 7.6;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 4.7;MCF7: 5.6;RH-30: 4.6;SCLC-21H: 4.6;SH-SY5Y: 5.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.2" HPA009708 Approved "Nuclear speckles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear speckles" "HPA009708: AB_2668261" "unprognostic (1.56e-1)" "unprognostic (1.45e-1)" "unprognostic (1.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.63e-2)" "unprognostic (2.17e-1)" "unprognostic (3.52e-2)" "unprognostic (7.23e-3)" "unprognostic (2.42e-1)" "unprognostic (1.98e-1)" "unprognostic (3.81e-1)" "unprognostic (2.16e-1)" "unprognostic (7.74e-3)" "unprognostic (6.63e-3)" "unprognostic (4.65e-1)" "unprognostic (6.67e-3)" "unprognostic (2.18e-2)" 1.5 0.4 1.8 0.1 1.0 0.0 1.1 5.4 1.6 0.9 0.6 0.6 0.0 1.0 0.0 0.4 0.7 0.0 0.6 1.9 2.6 0.4 0.0 0.5 0.0 0.9 1.0 0.7 1.2 0.2 0.9 0.2 1.0 0.7 0.0 11.1 0.8 0.0 0.5 1.2 0.3 0.3 0.7 0.0 0.2 0.2 1.6 0.0 0.2 0.1 0.0 0.5 0.4 1.0 1.5 3.6 0.8 4.7 1.2 0.7 2.6 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.5 0.2 1.8 0.0 0.1 0.0 3.0 0.0 0.0 2.1 0.6 0.0 0.0 1.2 0.0 0.2 0.0 1.3 0.4 0.2 0.0 0.0 1.8 5.6 0.0 0.0 2.0 0.0 0.0 0.0 4.6 0.0 1.5 1.2 4.6 5.6 3.7 0.0 2.1 0.1 2.1 0.2 0.9 2.2 0.5 1.1 0.9 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.0 5.4 1.6 1.9 2.6 0.9 1.0 1.0 0.7 1.6 1.0 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 9.5 1.4 1.4 0.1 0.0 0.1 0.0 16.7 0.1 0.1 0.2 1.9 1.2 0.1 0.0 0.1 1.5 0.0 0.0 0.6 0.6 0.4 1.4 0.0 0.0 0.0 0.0 1.1 0.1 0.0 11.8 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.8 0.0 4.2 7.6 0.0 2.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 19.5 0.0 0.8 0.8 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.0 ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 127.4;salivary gland: 139.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 197.3;Distal tubular cells: 49.0;Ionocytes: 321.4;Syncytiotrophoblasts: 64.9" "Group enriched" "Detected in many" 5 "ovarian cancer: 94.7;renal cancer: 23.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "BEWO: 21.6;HaCaT: 20.3;SK-BR-3: 49.2" "Not detected" "Not detected" "Not detected" "Not detected" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane" "CAB009523: AB_677577, HPA031847: AB_2674072" "unprognostic (2.28e-2)" "unprognostic (6.02e-2)" "unprognostic (2.20e-5)" "unprognostic (1.15e-2)" "unprognostic (3.96e-1)" "unprognostic (1.31e-1)" "unprognostic (2.22e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-2)" "unprognostic (1.48e-1)" "unprognostic (2.94e-2)" "unprognostic (1.40e-1)" "unprognostic (1.33e-3)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (3.63e-5)" "unprognostic (1.97e-2)" 2.2 0.5 0.5 0.2 0.3 0.0 11.8 0.7 0.9 31.1 0.0 0.6 0.5 1.4 1.2 1.6 12.8 0.2 1.1 0.2 0.0 127.4 0.2 1.7 0.5 0.1 0.0 1.2 3.3 0.8 4.2 17.9 0.1 2.0 0.1 3.9 139.8 1.4 0.5 32.5 0.6 0.8 0.0 0.0 0.3 0.3 0.0 0.1 0.3 0.2 0.0 0.6 0.8 0.3 0.4 0.3 0.6 1.3 2.6 3.1 21.6 0.4 0.2 0.0 0.0 0.1 2.0 0.1 0.2 1.2 0.0 20.3 0.7 0.0 0.0 0.5 0.6 0.0 0.3 0.3 0.0 0.0 0.0 1.5 0.1 0.0 0.3 3.1 0.0 0.1 0.0 0.0 0.2 1.2 0.1 0.3 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.2 0.5 1.5 0.7 49.2 0.1 2.7 0.6 0.0 0.4 0.6 0.2 0.9 0.5 0.0 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.7 0.9 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.7 3.2 0.0 0.3 0.0 0.1 1.3 1.7 0.0 0.9 5.6 3.7 0.4 0.0 13.9 0.0 8.4 197.3 0.1 0.6 49.0 0.1 1.5 0.0 0.1 1.1 0.0 0.0 1.0 0.6 38.3 3.8 0.0 0.1 0.0 0.0 0.0 0.1 11.7 1.7 0.4 0.0 321.4 0.0 0.3 0.1 0.0 0.1 30.2 0.0 0.0 0.5 1.0 1.0 0.1 0.4 0.0 1.2 0.0 0.6 0.3 0.2 2.6 3.8 0.0 1.1 1.0 0.4 1.2 0.0 0.4 64.9 0.1 0.1 0.1 0.6 AC007040.2 ENSG00000258881 "Novel protein" 2 70939318-70995336 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.2;retina: 1.4" "Cell type enriched" "Detected in single" 4 "Cytotrophoblasts: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.1;JURKAT: 2.4;U-2 OS: 2.1" NA NA "Cluster 6: Brain - Smell perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (1.86e-1)" "unprognostic (2.94e-1)" "unprognostic (7.99e-4)" "unprognostic (1.36e-1)" "unprognostic (9.49e-2)" "unprognostic (1.78e-3)" "unprognostic (2.35e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-1)" "unprognostic (1.95e-2)" "unprognostic (1.52e-1)" "unprognostic (2.93e-1)" "unprognostic (2.53e-9)" "unprognostic (6.54e-2)" "unprognostic (7.86e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" 0.1 0.0 0.6 0.1 0.6 0.2 0.1 1.2 1.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.6 0.3 0.1 0.0 0.0 0.1 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.0 1.4 0.3 0.0 0.2 0.5 0.0 0.0 0.2 0.1 0.0 0.8 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.9 1.1 0.1 0.1 0.6 0.1 0.1 0.4 0.0 0.0 0.2 0.2 0.1 0.1 1.6 0.1 0.2 3.1 0.2 0.4 0.0 0.3 1.3 1.0 1.0 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.6 2.4 0.1 0.4 0.2 0.3 0.1 0.1 0.1 0.2 0.1 1.3 0.4 0.0 0.3 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.3 0.0 0.4 1.2 2.1 0.3 1.0 0.1 0.0 0.0 1.3 0.5 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.6 1.2 1.0 0.6 0.3 0.5 0.4 0.6 0.2 0.5 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 ANKRD53 "FLJ12056, FLJ36160" ENSG00000144031 "Ankyrin repeat domain 53" Q8N9V6 2 70978380-70985499 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.5" "Group enriched" "Detected in many" 21 "Early spermatids: 158.6;Late spermatids: 481.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HHSteC: 1.6;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049574 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "HPA049574: AB_2680819" "unprognostic (6.11e-3)" "unprognostic (6.51e-2)" "unprognostic (1.70e-3)" "unprognostic (2.68e-1)" "unprognostic (2.01e-2)" "unprognostic (6.31e-3)" "unprognostic (2.20e-1)" "unprognostic (6.35e-2)" "unprognostic (3.53e-1)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-2)" "unprognostic (1.68e-3)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" 7.5 1.7 0.3 0.6 0.2 0.3 6.1 1.5 0.5 1.8 0.0 1.9 0.7 1.8 0.4 0.7 3.0 0.7 1.3 0.3 0.2 0.8 0.6 1.3 0.3 0.8 0.4 4.1 8.2 0.3 3.2 0.3 0.2 2.0 0.2 6.1 4.5 0.6 0.4 0.8 1.7 0.6 0.3 0.8 2.0 27.5 0.1 0.1 3.1 0.3 0.3 1.6 1.6 0.2 0.0 0.0 0.1 0.1 1.0 0.4 0.1 0.1 0.4 0.4 0.4 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.6 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.3 0.2 1.5 0.5 0.3 0.2 0.8 0.4 0.2 0.3 0.1 0.2 1.1 0.0 0.0 0.3 1.1 0.1 1.4 0.5 4.6 1.3 0.3 1.3 0.4 1.5 0.1 0.0 2.1 0.1 1.0 0.0 0.0 1.2 158.6 4.3 0.5 0.7 0.0 0.4 0.4 0.4 1.0 1.9 1.1 2.2 0.0 0.4 1.1 0.2 0.0 1.7 1.2 0.0 0.0 0.0 0.4 481.3 3.4 0.4 0.0 0.0 0.0 4.1 0.0 1.5 0.3 0.5 0.0 3.0 11.7 0.7 0.1 1.5 0.6 15.1 6.6 2.8 1.5 1.5 1.7 0.6 0.0 0.3 0.4 0.1 0.1 0.1 TEX261 "MGC32043, TEG-261" ENSG00000144043 "Testis expressed 261" Q6UWH6 2 70985942-70994873 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA016631 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA016631: AB_2240434" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (4.23e-4)" "unprognostic (5.52e-3)" "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (3.15e-2)" "unprognostic (3.70e-3)" "unprognostic (3.36e-1)" "unprognostic (5.59e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.99e-1)" 39.5 38.8 30.8 21.5 34.8 20.0 29.7 33.1 31.2 32.2 39.1 28.3 25.0 25.4 45.5 27.5 35.3 22.7 36.0 29.3 32.7 41.1 38.8 30.4 22.0 38.5 34.5 39.6 47.5 66.1 29.2 25.0 33.5 31.6 32.7 43.9 36.0 34.3 56.4 20.9 25.6 34.0 32.9 23.5 30.0 36.9 33.4 25.7 46.1 54.3 27.0 26.2 21.6 33.4 61.9 57.1 39.4 50.3 116.4 58.9 44.7 69.8 65.6 79.1 49.6 67.5 49.8 50.2 25.9 122.5 74.7 45.6 75.3 82.7 113.8 38.4 62.8 60.1 28.7 71.8 68.3 70.7 48.7 53.7 54.3 76.2 51.6 43.4 81.5 51.3 75.7 32.4 93.6 48.2 61.2 39.3 26.2 98.7 66.4 43.1 120.7 43.1 57.7 53.1 64.0 33.8 72.3 70.9 46.0 26.2 46.3 41.3 66.1 96.8 83.6 52.4 93.8 25.3 23.9 58.4 84.4 91.7 83.2 8.7 3.8 7.7 3.4 3.9 2.9 1.8 3.7 4.6 2.9 2.7 4.1 3.3 2.8 2.6 3.9 3.1 3.3 2.1 30.8 34.8 33.1 31.2 29.3 32.7 38.5 34.5 33.5 32.9 33.4 33.4 14.7 3.2 14.7 9.4 11.3 8.3 10.7 8.2 5.7 14.7 20.6 14.9 22.9 20.0 8.4 23.9 37.5 16.4 9.0 21.8 7.9 24.9 15.7 10.8 11.9 15.5 8.4 17.4 8.0 23.8 17.4 16.3 12.2 13.3 2.5 17.1 16.4 35.2 19.5 8.4 7.5 18.2 8.2 18.3 6.4 28.5 15.8 11.9 19.6 6.5 13.0 28.1 14.4 15.1 12.6 21.1 14.9 18.4 7.4 12.9 24.4 18.3 5.5 72.9 0.0 16.7 15.0 45.3 11.2 12.8 7.5 17.9 8.7 14.4 18.9 7.7 NAGK GNK ENSG00000124357 "N-acetylglucosamine kinase" Q9UJ70 2 71064344-71079808 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 216.9;Syncytiotrophoblasts: 318.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 391.8;granulocytes: 288.7;monocytes: 594.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035206, HPA035207" Enhanced Approved Nucleoplasm,Cytosol NA NA 1000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol Nucleoplasm "HPA035206: AB_2674517, HPA035207: AB_10602031" "unprognostic (6.15e-2)" "unprognostic (4.23e-3)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.44e-1)" "prognostic favorable (5.87e-4)" "unprognostic (4.65e-3)" "unprognostic (2.18e-2)" "unprognostic (2.31e-1)" "unprognostic (9.99e-2)" "unprognostic (4.32e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.35e-4)" "unprognostic (8.60e-2)" "unprognostic (1.45e-2)" "unprognostic (5.50e-3)" "unprognostic (2.13e-2)" 41.2 36.0 47.0 61.2 48.0 21.9 35.1 49.5 52.1 57.5 47.0 37.7 21.0 33.6 40.6 156.2 29.0 44.1 31.4 46.9 52.9 35.1 42.8 39.6 79.6 50.9 50.4 31.0 42.2 80.7 42.3 44.3 53.7 30.0 34.2 16.5 75.0 37.9 26.6 63.0 33.6 50.1 48.3 88.9 33.9 50.2 49.0 60.8 27.4 32.3 98.4 71.7 59.7 52.1 55.9 39.2 22.6 25.8 114.2 67.5 98.3 119.0 65.5 95.6 86.8 54.3 29.5 30.3 29.3 107.4 113.5 25.7 22.4 43.9 62.7 44.9 16.4 17.0 12.6 37.5 91.6 10.5 37.7 60.7 49.6 101.8 16.4 68.3 107.7 31.7 8.1 34.8 143.4 52.2 28.6 40.2 28.7 53.5 38.4 22.1 64.2 15.8 65.5 91.4 25.1 13.0 35.2 62.1 45.1 50.7 30.4 13.9 66.0 99.0 37.8 36.9 44.8 23.0 24.8 18.0 69.6 31.5 54.5 86.6 594.1 245.1 36.9 526.5 39.2 102.5 44.2 37.0 391.8 103.7 36.7 30.0 288.7 65.3 378.2 318.5 54.7 466.2 47.0 48.0 49.5 52.1 46.9 52.9 50.9 50.4 53.7 48.3 49.0 52.1 22.9 38.5 34.2 15.0 48.6 26.9 28.4 60.8 19.4 46.1 27.4 27.6 18.0 17.2 56.9 38.6 22.9 146.0 67.4 13.9 41.1 66.1 151.3 22.5 26.1 31.7 23.4 12.8 11.5 45.7 144.0 35.6 15.8 24.9 51.9 31.1 30.0 12.9 216.9 47.1 15.2 20.4 28.5 121.8 67.5 33.0 30.1 106.0 39.2 26.2 118.6 45.4 17.5 17.1 24.0 59.1 32.3 37.6 51.2 15.5 23.3 64.7 35.2 55.6 19.7 31.8 37.4 68.0 25.6 39.9 41.6 318.8 29.1 32.2 16.2 34.7 MCEE "GLOD2, MCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 92.0;Proximal tubular cells: 77.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035196 Approved Nucleoli "Intracellular and membrane" No No 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoli "HPA035196: AB_10601871" "unprognostic (7.65e-2)" "unprognostic (8.20e-2)" "unprognostic (3.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.35e-1)" "prognostic favorable (4.76e-4)" "prognostic favorable (5.78e-4)" "unprognostic (4.86e-3)" "unprognostic (6.48e-2)" "unprognostic (1.08e-1)" "unprognostic (7.43e-3)" "unprognostic (8.59e-2)" "unprognostic (9.40e-3)" "unprognostic (4.90e-2)" "unprognostic (3.55e-1)" "unprognostic (6.51e-2)" "unprognostic (5.38e-2)" 17.8 30.0 8.9 12.3 9.7 9.1 32.7 10.5 12.5 22.1 15.4 20.1 20.1 13.1 30.5 26.3 14.8 14.2 35.9 8.9 9.4 33.7 69.8 13.7 14.7 9.5 9.1 18.5 36.1 35.6 24.1 17.6 9.9 23.9 23.9 12.3 42.8 17.8 36.5 28.4 16.9 12.2 9.7 16.0 23.5 6.0 9.4 13.3 14.1 61.7 15.5 16.5 21.9 11.7 12.1 5.2 10.6 7.6 34.3 46.6 30.2 18.5 23.3 9.2 13.9 14.7 14.8 18.7 5.5 18.5 7.0 12.5 12.4 9.6 9.5 17.1 10.7 12.7 16.3 42.5 19.5 14.5 10.3 31.3 13.5 6.2 12.3 20.5 10.6 14.6 17.1 31.9 9.1 15.5 10.9 16.9 9.6 33.1 14.6 12.8 12.3 35.2 14.8 10.4 11.9 8.8 6.9 40.1 18.1 12.1 31.7 13.4 13.7 10.6 8.3 10.9 7.5 30.7 13.1 20.0 17.5 23.7 9.9 20.3 23.2 27.6 15.4 25.6 21.9 21.6 19.3 15.5 19.9 16.7 17.6 15.0 6.1 16.5 25.3 23.9 35.3 14.6 8.9 9.7 10.5 12.5 8.9 9.4 9.5 9.1 9.9 9.7 9.4 11.7 11.1 25.6 13.4 13.7 12.8 8.5 10.5 18.4 21.6 2.6 37.5 27.3 75.2 25.8 18.2 5.5 2.1 36.2 11.2 14.0 92.0 13.3 1.1 17.2 16.2 9.0 9.0 12.0 13.3 18.4 36.8 23.3 17.3 20.2 0.0 5.2 12.8 73.0 15.1 5.0 14.5 32.5 18.3 10.4 8.7 1.0 29.2 9.4 14.2 14.0 9.1 7.3 5.2 16.1 20.8 9.6 16.2 17.7 42.0 11.0 35.0 77.1 19.4 8.6 26.3 12.7 17.9 3.7 5.1 25.6 20.9 11.4 10.1 16.9 23.0 11.9 MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130632-71150101 "Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: AB_2674436, HPA035060: AB_10601875, HPA049907: AB_2680947" "unprognostic (3.20e-3)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (6.41e-3)" "unprognostic (6.13e-2)" "unprognostic (3.50e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (3.89e-7)" "unprognostic (1.24e-1)" "unprognostic (2.91e-1)" "unprognostic (2.47e-1)" "unprognostic (2.23e-2)" 22.6 18.4 15.2 20.4 16.4 26.5 25.0 17.7 21.4 19.9 15.4 17.6 17.7 22.1 27.5 28.6 16.6 18.4 23.2 15.3 17.7 17.8 30.8 16.9 25.2 17.1 17.0 25.9 19.7 22.9 15.8 20.3 17.0 24.6 19.1 15.1 21.0 16.7 33.1 26.7 15.5 16.8 15.6 19.6 17.8 15.4 16.3 22.5 21.7 24.0 27.5 23.8 18.1 17.6 45.8 33.7 42.7 51.3 39.1 36.7 58.3 49.8 39.6 40.6 29.7 60.7 32.9 64.3 30.5 35.3 31.0 41.1 54.8 35.3 54.1 44.7 43.2 77.3 26.3 139.1 34.1 101.0 58.2 32.0 44.4 33.4 44.4 27.4 34.8 39.1 113.5 49.1 41.0 49.1 81.6 101.5 71.0 63.5 38.1 66.6 66.7 75.4 33.1 49.0 51.8 40.0 33.6 75.0 49.9 36.1 38.2 44.5 36.0 47.2 51.1 45.3 64.0 41.0 50.6 104.1 40.5 82.8 49.1 17.6 12.4 9.8 15.2 17.8 20.2 18.0 19.6 18.8 15.3 15.0 21.4 19.2 1.9 17.1 26.1 16.3 18.3 11.3 15.2 16.4 17.7 21.4 15.3 17.7 17.1 17.0 17.0 15.6 16.3 17.6 38.6 35.3 55.5 8.1 36.8 33.4 42.7 37.8 30.7 37.2 26.0 36.8 44.5 30.0 53.0 18.4 4.2 50.5 47.7 17.9 25.4 47.8 6.0 40.4 52.4 40.4 18.0 26.9 9.8 41.8 48.1 43.2 19.9 65.4 48.1 31.2 21.8 33.2 27.2 18.5 11.4 21.6 26.4 17.7 20.8 6.3 48.7 19.0 12.4 15.0 39.2 25.5 47.4 12.1 15.9 33.1 15.0 43.6 25.6 40.6 14.2 22.7 29.2 53.2 39.5 62.2 49.1 70.2 84.5 35.6 33.5 32.4 39.9 42.8 28.2 31.9 PAIP2B KIAA1155 ENSG00000124374 "Poly(A) binding protein interacting protein 2B" Q9ULR5 2 71182738-71227103 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 181.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 86.0;Early spermatids: 95.1;Hepatocytes: 67.1;Proximal tubular cells: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 15.8;SCLC-21H: 23.1" "Low region specificity" "Detected in all" "HPA046784, HPA072371" Approved Approved Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol "HPA046784: AB_2679804, HPA072371: AB_2686514" "unprognostic (8.70e-2)" "unprognostic (8.20e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.17e-5)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (9.67e-3)" "unprognostic (1.51e-2)" "unprognostic (3.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.25e-2)" "unprognostic (2.76e-1)" "prognostic favorable (6.96e-12)" "unprognostic (1.63e-2)" "unprognostic (3.87e-1)" "unprognostic (1.21e-2)" "unprognostic (4.61e-2)" 2.4 1.6 131.5 1.8 159.1 1.3 4.5 108.3 176.8 3.1 66.3 3.8 3.7 2.9 1.8 6.1 7.2 1.1 23.0 94.7 116.5 10.3 18.1 2.7 2.1 134.9 136.6 11.5 54.2 6.0 2.2 0.6 143.0 4.8 3.7 27.7 37.9 3.5 48.5 16.4 2.7 1.7 132.8 2.2 10.5 2.2 130.3 2.4 11.6 26.7 4.6 2.8 4.0 181.5 2.5 0.6 1.0 3.6 0.4 0.5 4.4 0.3 0.1 0.3 0.2 0.9 1.0 3.2 0.6 0.0 2.4 2.0 6.1 3.7 1.2 1.7 5.0 3.1 0.4 0.1 1.6 0.8 0.2 0.6 3.3 0.2 3.6 0.9 0.6 7.2 5.5 3.0 0.2 3.2 1.0 1.7 2.6 5.8 2.3 0.0 10.5 15.8 1.9 1.7 23.1 1.3 2.6 1.7 1.1 5.5 7.5 0.2 0.1 0.3 1.9 1.9 1.0 6.1 5.5 3.9 0.2 1.1 0.5 0.5 0.3 0.5 1.0 0.4 1.2 2.5 1.3 1.0 0.4 2.6 2.1 1.9 0.2 0.8 0.4 2.3 0.6 0.6 131.5 159.1 108.3 176.8 94.7 116.5 134.9 136.6 143.0 132.8 130.3 181.5 3.3 3.2 4.5 5.2 9.9 7.8 7.0 4.0 5.7 11.3 14.8 8.8 86.0 12.8 2.7 7.3 6.2 3.2 13.2 2.7 21.5 4.9 95.1 18.4 3.9 3.9 41.5 15.6 4.2 41.3 9.2 4.7 11.2 17.5 1.3 7.5 7.1 67.1 1.9 6.7 4.6 6.3 14.2 3.2 1.6 30.0 5.3 2.6 14.2 2.8 2.4 12.3 4.1 2.5 31.9 10.4 4.0 5.3 29.9 9.4 1.3 56.9 15.5 43.3 0.0 9.3 4.0 32.9 7.7 17.3 20.0 6.3 4.7 4.3 8.1 6.0 ZNF638 "MGC26130, NP220, ZFML, Zfp638" ENSG00000075292 "Zinc finger protein 638" Q14966 2 71276561-71435069 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 342.3;Oligodendrocytes: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036784, HPA057395" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA036784: AB_10672478, HPA057395: AB_2683426" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (7.57e-2)" "unprognostic (1.26e-3)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-2)" "unprognostic (5.68e-3)" "unprognostic (2.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (2.66e-3)" "unprognostic (3.28e-1)" "unprognostic (7.68e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.73e-5)" 21.1 22.1 35.7 21.6 48.9 28.2 24.6 77.6 52.3 23.0 37.7 22.0 15.6 29.2 18.4 19.8 22.1 19.1 41.0 35.7 41.3 24.2 30.9 21.2 25.0 41.9 36.8 37.3 21.9 27.9 24.9 23.2 41.9 22.2 19.5 48.6 21.0 19.5 51.5 16.8 19.0 22.9 34.8 23.1 21.8 29.7 38.9 30.9 29.8 33.7 22.6 21.3 17.1 82.5 36.2 51.0 77.0 36.1 44.4 48.3 59.2 40.4 46.6 33.6 30.0 49.2 34.6 59.2 36.6 37.1 52.3 29.9 72.1 41.4 48.7 60.5 40.1 77.8 54.8 45.4 38.3 72.0 50.6 30.8 39.5 36.1 66.7 47.8 52.5 39.2 79.4 33.8 49.6 36.1 50.9 52.9 66.7 54.1 32.4 43.0 116.5 41.7 36.0 54.3 59.0 38.7 49.8 34.7 52.8 76.3 32.3 43.7 54.3 41.4 60.0 31.1 41.2 27.6 45.7 57.4 34.8 46.3 45.8 64.1 17.0 33.5 18.1 16.3 17.2 25.4 17.1 17.2 14.0 26.0 22.5 16.7 29.1 21.5 24.1 17.7 16.0 10.8 35.7 48.9 77.6 52.3 35.7 41.3 41.9 36.8 41.9 34.8 38.9 82.5 63.1 67.3 112.4 227.9 63.9 31.7 56.8 40.8 46.1 111.5 36.8 35.4 107.0 27.1 59.0 40.5 123.0 42.5 46.7 39.2 19.6 43.0 15.7 54.2 63.7 65.9 38.4 57.2 286.9 40.9 29.0 83.5 50.0 59.2 79.1 112.8 38.6 48.6 32.5 67.3 268.4 34.2 32.6 41.9 33.3 15.8 75.2 49.6 23.2 225.8 71.6 56.4 56.7 342.3 619.5 39.6 35.7 63.9 50.5 60.0 38.1 21.6 74.7 104.0 32.9 98.3 73.1 110.1 78.3 37.4 30.3 50.2 56.1 74.0 36.8 58.9 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;skin 1: 31.4" "Group enriched" "Detected in many" 4 "Leydig cells: 75.8;Peritubular cells: 229.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 9.8;HaCaT: 14.8;RH-30: 18.4;U-2 OS: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA012567 Uncertain Approved Cytosol "Intracellular and membrane" No No "Cluster 27: Brain & Skin - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "HPA012567: AB_1847429" "unprognostic (1.70e-1)" "unprognostic (1.05e-1)" "unprognostic (8.76e-2)" "unprognostic (2.19e-4)" "unprognostic (3.46e-2)" "unprognostic (4.40e-1)" "unprognostic (2.17e-4)" "unprognostic (8.41e-2)" "unprognostic (1.51e-1)" "unprognostic (1.40e-1)" "unprognostic (7.55e-3)" "unprognostic (1.52e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (9.44e-3)" "unprognostic (2.04e-2)" 26.2 4.3 12.0 1.9 3.3 0.1 15.0 12.3 7.0 5.0 0.4 3.2 3.7 2.5 1.5 3.9 5.5 1.1 8.5 6.7 1.3 8.8 1.0 2.7 4.9 48.0 10.4 4.5 0.6 0.8 9.3 3.3 49.9 2.6 1.2 4.2 9.9 7.3 5.9 31.4 4.7 1.6 0.0 3.5 1.2 13.8 0.7 19.3 14.4 2.3 2.9 3.2 4.2 3.5 0.6 5.9 0.0 0.1 9.8 4.0 5.9 0.9 0.1 0.2 0.2 1.8 0.5 0.0 0.5 0.7 3.0 14.8 8.5 0.0 0.1 0.0 2.7 0.0 7.0 0.9 0.2 0.0 0.3 0.0 0.5 0.0 0.3 3.0 1.1 4.0 0.6 0.1 0.9 2.9 0.0 0.1 0.0 0.1 1.0 0.1 18.4 0.0 0.0 1.3 0.6 0.1 3.0 0.0 3.5 1.2 0.3 0.9 0.0 1.6 19.3 9.0 3.0 0.1 1.2 0.0 6.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 3.3 12.3 7.0 6.7 1.3 48.0 10.4 49.9 0.0 0.7 3.5 2.4 0.0 0.0 2.0 1.2 14.7 1.1 0.8 0.6 0.2 2.3 0.8 1.4 4.3 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.2 4.1 0.2 0.2 19.0 1.8 5.3 5.3 0.0 0.9 15.6 0.0 0.3 0.0 1.5 34.6 0.8 0.1 0.0 0.7 0.0 0.0 6.1 19.1 9.6 75.8 0.4 7.2 0.0 0.0 7.4 0.0 2.0 0.5 0.4 1.5 229.9 0.0 0.5 0.2 0.1 0.2 0.3 0.0 5.7 20.7 1.5 3.8 1.6 9.7 0.1 0.8 7.5 0.1 0.4 EXOC6B "KIAA0919, SEC15B, SEC15L2" ENSG00000144036 "Exocyst complex component 6B" Q9Y2D4 2 72175984-72826041 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.7" "Cell type enhanced" "Detected in many" "Astrocytes: 210.3;Excitatory neurons: 351.1;Inhibitory neurons: 393.6;Microglial cells: 286.7;Oligodendrocyte precursor cells: 288.5;Oligodendrocytes: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034546, HPA063991" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nuclear bodies" Cytosol "HPA034546: AB_2674218, HPA063991: AB_2685168" "unprognostic (5.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.92e-1)" "unprognostic (1.18e-3)" "unprognostic (1.81e-1)" "unprognostic (7.56e-2)" "unprognostic (1.06e-2)" "unprognostic (9.34e-2)" "unprognostic (1.32e-1)" "unprognostic (2.16e-3)" "unprognostic (3.38e-2)" "unprognostic (2.61e-1)" "unprognostic (4.35e-3)" "unprognostic (4.38e-3)" "unprognostic (1.55e-1)" "unprognostic (1.18e-1)" "unprognostic (5.29e-2)" 11.3 13.4 22.3 4.2 32.7 1.2 8.6 18.8 23.9 12.6 3.2 8.6 7.3 10.1 6.0 15.1 7.8 6.5 50.7 20.7 25.7 7.2 3.8 7.2 3.1 23.9 25.7 15.0 5.0 13.2 6.1 13.0 23.3 8.0 5.7 14.1 7.7 8.9 11.1 26.5 9.1 10.0 16.4 5.2 6.9 6.9 22.2 4.4 10.2 11.5 6.4 9.7 13.0 40.9 21.7 16.3 14.7 17.8 41.2 16.9 25.3 15.6 21.9 13.2 8.6 22.3 3.3 5.6 9.5 26.2 19.6 35.4 12.4 25.7 18.9 4.2 10.1 16.7 11.0 12.8 22.2 2.4 5.5 14.6 36.6 14.9 23.1 20.6 21.8 8.7 1.8 0.0 17.6 7.5 6.4 2.9 15.3 14.9 9.0 3.4 26.4 2.3 12.7 50.1 7.3 6.3 26.7 8.2 10.9 16.1 5.7 2.3 24.3 15.2 12.8 13.1 9.6 5.5 5.9 0.0 17.7 1.2 12.4 1.3 0.5 0.0 0.7 0.4 0.5 0.7 0.5 0.4 0.4 0.7 0.6 0.9 0.0 0.5 0.6 0.1 0.8 0.4 22.3 32.7 18.8 23.9 20.7 25.7 23.9 25.7 23.3 16.4 22.2 40.9 17.8 0.0 4.1 210.3 4.1 26.1 10.2 9.8 14.8 17.4 5.2 5.2 87.1 12.8 5.1 9.2 25.0 15.1 5.0 10.2 5.9 9.3 62.9 5.6 14.5 14.1 3.0 2.1 351.1 11.5 13.2 12.4 30.5 9.2 8.2 11.6 11.4 5.6 4.6 16.8 393.6 6.0 4.1 12.0 7.1 8.2 8.4 5.0 5.4 286.7 2.0 9.9 1.0 288.5 863.3 11.0 8.6 7.5 3.7 8.1 28.2 5.5 8.4 11.1 0.0 13.5 14.7 12.0 4.9 13.1 37.4 24.6 4.7 5.5 4.5 10.7 SPR SDR38C1 ENSG00000116096 "Sepiapterin reductase" P35270 2 72887382-72892158 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 85.3;Exocrine glandular cells: 81.1;Proximal tubular cells: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 8.3;intermediate monocyte: 2.4;myeloid DC: 8.9" "Group enriched" "Detected in many" 11 "dendritic cells: 8.9;monocytes: 8.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039505 Uncertain Supported Nucleoplasm,Cytosol NA NA 180000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA039505: AB_10795466" "unprognostic (4.09e-1)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (1.97e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-2)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (9.79e-2)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (7.50e-3)" "unprognostic (2.87e-1)" "unprognostic (1.43e-3)" "unprognostic (1.95e-1)" 25.9 50.8 26.0 7.6 27.2 0.6 20.0 27.2 61.4 14.5 39.6 36.4 23.4 13.4 36.9 19.7 26.3 11.9 44.4 26.8 30.0 44.2 99.8 15.9 3.2 27.9 31.5 12.2 63.5 38.4 10.9 6.8 29.8 26.2 32.5 3.1 31.2 16.7 43.9 9.1 22.0 11.5 27.9 9.6 42.1 7.3 28.5 2.4 20.5 25.4 5.1 25.2 13.7 28.0 47.5 130.9 0.6 20.0 51.2 18.5 31.8 21.4 31.8 16.0 15.0 84.0 48.0 34.5 25.4 26.1 80.6 43.9 58.1 35.1 13.3 10.0 43.7 51.7 30.8 87.4 19.1 8.2 13.6 16.7 38.7 17.6 19.7 32.7 42.6 25.4 54.0 6.8 21.4 100.5 3.3 31.1 10.9 139.9 118.7 0.0 82.8 20.3 85.8 73.4 8.0 14.6 39.6 89.7 31.0 16.9 40.4 9.9 52.8 17.4 42.2 30.5 38.7 7.2 16.9 2.3 25.0 17.6 31.0 0.0 8.3 0.7 0.3 2.4 0.3 0.0 0.1 0.1 8.9 0.0 0.1 0.3 0.0 0.0 0.9 0.9 0.0 2.4 26.0 27.2 27.2 61.4 26.8 30.0 27.9 31.5 29.8 27.9 28.5 28.0 13.8 12.8 7.3 0.3 1.1 8.4 23.0 14.8 20.5 0.7 22.2 16.5 46.2 38.6 10.8 42.3 0.0 18.1 0.4 85.3 21.5 56.9 0.3 12.5 4.2 16.7 11.4 6.6 0.7 81.1 10.6 13.9 26.0 6.7 4.5 8.4 17.2 62.9 42.1 1.7 0.4 39.6 12.2 6.0 7.4 1.5 9.3 9.7 14.2 1.9 20.8 13.8 0.0 0.0 0.3 43.3 50.4 5.7 1.4 33.9 71.0 91.6 11.2 0.7 6.6 8.3 8.6 0.4 10.2 17.8 6.5 4.4 1.9 8.7 57.8 15.6 EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 13.1;kidney: 36.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 55.2;Excitatory neurons: 13.0;Proximal tubular cells: 35.7" "Cancer enriched" "Detected in some" 5 "renal cancer: 3.7" "Region enriched" "Detected in some" 10 "cerebral cortex: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.3;CACO-2: 3.7;HEK 293: 8.3;HMC-1: 1.6;RPTEC TERT1: 1.4;U-2 OS: 1.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "amygdala: 2.7;cerebral cortex: 10.5;hippocampal formation: 7.8" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: AB_2667542, HPA006421: AB_1078739" "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (8.71e-2)" "unprognostic (2.22e-6)" "unprognostic (4.82e-2)" "unprognostic (1.70e-1)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (2.99e-1)" "unprognostic (3.07e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (1.08e-3)" "unprognostic (5.02e-2)" 0.2 0.1 0.1 0.0 1.3 0.0 0.0 0.0 13.1 0.0 0.0 0.4 0.8 0.0 0.7 0.1 0.0 0.0 0.0 1.3 0.0 36.4 0.1 0.0 0.0 0.0 0.0 0.0 0.3 5.9 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 3.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.3 0.0 0.0 1.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 13.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 55.2 0.0 0.1 0.0 1.2 5.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.0 0.0 0.0 1.6 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 35.7 0.0 0.0 0.0 0.0 0.0 1.5 5.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 SFXN5 "BBG-TCC, SLC56A5" ENSG00000144040 "Sideroflexin 5" Q8TD22 2 72942036-73075619 "Predicted intracellular proteins, Predicted membrane proteins" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 63.6" "Cell type enhanced" "Detected in many" "Astrocytes: 405.2;Early spermatids: 96.4;Late spermatids: 168.4" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015473, HPA056866" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 11: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Mitochondria" "HPA015473: AB_1856794, HPA056866: AB_2683261" "unprognostic (7.75e-2)" "unprognostic (1.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-3)" "unprognostic (1.21e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (1.22e-1)" "prognostic favorable (2.26e-6)" "unprognostic (1.57e-1)" "unprognostic (8.51e-2)" "unprognostic (3.50e-1)" "unprognostic (3.23e-1)" "unprognostic (3.97e-1)" "unprognostic (1.43e-2)" 3.2 11.7 52.1 4.6 45.5 13.7 2.5 40.0 63.6 3.2 21.9 6.1 6.9 3.1 16.6 3.1 4.2 4.0 3.5 48.0 45.2 11.4 29.4 3.6 3.9 51.5 49.2 2.6 2.4 2.0 3.5 3.7 41.4 4.2 5.7 6.2 2.2 4.5 7.7 4.5 6.5 3.9 42.6 5.6 4.6 2.4 57.0 4.9 3.7 4.6 3.0 3.8 2.3 37.4 4.2 9.1 13.7 11.5 3.0 5.0 5.4 8.4 5.4 13.3 6.9 13.7 10.7 2.3 8.8 8.9 9.2 3.7 10.8 11.1 6.0 10.2 6.7 10.7 11.0 18.7 4.4 5.9 11.1 5.8 3.5 9.0 1.1 4.9 7.4 3.2 9.5 2.9 4.3 8.7 1.5 9.5 17.1 8.1 6.6 10.6 12.2 3.1 8.1 10.5 9.0 2.7 8.6 4.3 3.5 7.7 2.2 5.3 6.8 4.1 13.5 6.1 10.2 4.0 4.1 3.1 15.0 10.3 5.3 4.7 6.0 3.5 0.6 2.6 0.9 1.6 0.3 0.7 2.7 2.4 0.4 0.5 4.6 4.3 3.2 1.9 0.7 1.7 52.1 45.5 40.0 63.6 48.0 45.2 51.5 49.2 41.4 42.6 57.0 37.4 7.1 0.0 4.4 405.2 4.8 4.7 4.3 7.6 4.6 26.8 6.9 5.5 5.8 7.2 4.8 36.8 33.3 12.4 6.8 18.4 3.9 5.1 96.4 5.1 13.1 7.6 13.8 13.7 84.4 9.1 2.4 8.9 9.2 11.2 0.0 42.8 9.3 61.3 12.4 20.2 57.4 8.6 2.0 8.7 9.6 168.4 10.5 9.6 8.8 43.1 19.7 65.8 10.3 40.2 29.9 8.0 6.5 11.3 7.1 3.6 17.5 22.2 3.2 42.3 13.1 12.2 8.8 11.2 15.7 7.3 9.2 4.2 6.3 15.9 8.8 2.3 RAB11FIP5 "GAF1, KIAA0857, pp75, RIP11" ENSG00000135631 "RAB11 family interacting protein 5" Q9BXF6 2 73073382-73156721 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.7" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Late spermatids: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036406, HPA036407" Enhanced Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Centriolar satellite" "HPA036406: AB_2675105, HPA036407: AB_10669778" "unprognostic (1.49e-1)" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.58e-3)" "unprognostic (4.08e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (3.23e-3)" "unprognostic (1.45e-1)" "prognostic favorable (2.26e-5)" "unprognostic (1.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "unprognostic (9.66e-3)" 8.0 5.3 5.2 2.3 4.7 0.5 7.5 2.3 19.8 6.9 0.0 6.5 2.0 10.6 1.5 5.8 7.5 3.7 6.6 6.0 6.2 11.7 2.3 6.8 1.0 17.4 6.2 6.9 7.4 12.2 5.4 1.7 16.1 5.1 0.8 0.8 7.5 3.3 11.5 8.2 3.4 3.2 4.2 14.3 5.9 44.7 11.6 0.4 5.1 3.0 0.9 6.7 5.8 6.0 20.0 8.8 0.6 6.2 6.7 7.9 11.1 28.6 15.9 10.1 8.0 6.9 4.4 0.0 15.3 16.3 10.7 8.1 4.1 8.6 4.4 38.1 11.1 7.8 4.0 4.2 7.8 0.0 1.4 9.5 8.9 12.5 8.3 9.3 13.5 3.6 6.0 3.6 7.1 0.6 0.1 0.2 4.8 3.2 15.0 7.1 7.8 18.3 8.7 2.7 2.8 2.9 10.0 3.3 4.3 2.1 2.2 0.5 35.4 24.4 13.2 17.3 15.0 13.8 4.3 0.1 18.0 8.5 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 5.2 4.7 2.3 19.8 6.0 6.2 17.4 6.2 16.1 4.2 11.6 6.0 12.1 6.4 3.6 4.6 1.3 25.5 8.3 6.7 12.5 4.4 13.0 6.9 12.0 12.8 3.7 20.2 0.0 1.2 5.5 7.7 27.4 12.1 86.2 6.1 3.2 20.4 1.8 0.0 11.1 18.4 12.2 9.0 3.1 12.8 0.0 34.5 16.8 6.1 2.1 6.7 11.5 2.5 2.0 1.3 8.1 171.6 14.3 1.9 8.8 7.5 1.0 7.4 1.0 1.0 1.3 22.7 2.7 8.6 6.1 13.4 0.4 46.9 5.0 2.6 26.3 7.2 6.2 39.8 6.6 5.1 17.6 14.8 4.5 6.4 4.6 16.4 NOTO ENSG00000214513 "Notochord homeobox" A8MTQ0 2 73202574-73212513 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Microglial cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034660, HPA063906" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA034660: AB_10601974, HPA063906: " "unprognostic (6.09e-2)" "unprognostic (9.77e-2)" "unprognostic (4.84e-2)" "unprognostic (1.09e-1)" "unprognostic (6.66e-2)" "unprognostic (1.68e-2)" 0.0 0.1 0.3 0.1 0.2 0.5 0.0 0.6 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.3 0.2 0.6 0.3 0.2 0.2 0.5 0.3 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMYD5 "NN8-4AG, RAI15, RRG1, ZMYND23" ENSG00000135632 "SMYD family member 5" Q6GMV2 2 73214222-73227221 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015514, HPA049002" Uncertain Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA015514: AB_2669205, HPA049002: AB_2680595" "unprognostic (1.75e-1)" "unprognostic (3.39e-1)" "unprognostic (5.22e-2)" "unprognostic (6.66e-3)" "unprognostic (3.86e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (6.58e-7)" "unprognostic (1.28e-1)" "unprognostic (1.60e-2)" "unprognostic (3.84e-2)" "unprognostic (3.84e-1)" "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (3.94e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (2.40e-1)" 13.3 19.1 27.2 12.1 27.8 11.6 14.8 24.3 30.5 15.5 22.0 12.5 7.3 14.4 19.4 14.1 19.5 7.3 17.9 28.2 28.0 18.8 15.2 9.8 13.1 28.9 26.5 28.3 18.4 17.9 15.4 13.1 28.8 15.4 11.3 13.0 12.2 13.4 17.7 14.5 12.4 14.5 25.9 16.2 11.4 17.4 26.9 8.2 14.3 13.0 16.0 17.5 13.1 26.9 24.3 45.2 27.0 25.9 19.3 28.4 45.7 22.8 23.0 43.4 26.6 59.4 24.4 43.1 20.9 38.6 52.1 24.4 42.2 49.4 39.1 26.3 29.7 41.8 19.5 65.9 26.0 41.5 16.5 24.0 31.4 39.7 47.3 19.2 26.7 33.9 44.9 20.2 27.9 34.1 38.8 27.1 42.2 50.8 36.3 25.6 50.6 35.5 28.6 34.6 17.4 25.9 20.7 30.7 26.4 24.4 25.0 14.7 18.5 29.7 46.3 36.5 38.1 22.0 17.7 38.2 33.5 35.2 24.3 0.0 1.4 0.0 5.1 3.9 11.1 6.0 7.0 6.8 3.2 6.2 7.0 7.7 0.0 4.5 4.3 3.0 3.1 4.5 27.2 27.8 24.3 30.5 28.2 28.0 28.9 26.5 28.8 25.9 26.9 26.9 4.1 3.2 5.6 5.2 5.6 5.1 3.9 2.3 1.8 10.2 5.4 6.7 7.2 2.8 4.4 5.5 4.2 9.0 3.4 2.4 1.9 8.5 0.5 2.8 4.2 4.9 0.0 9.5 5.0 8.8 10.4 4.5 2.6 3.7 7.0 9.5 2.9 4.8 5.9 5.0 5.2 4.4 4.1 2.4 2.5 2.9 2.8 2.7 5.4 2.8 3.7 4.0 4.1 1.5 3.5 5.6 1.5 3.0 3.1 5.0 1.3 8.1 1.3 5.3 6.6 4.0 4.6 6.7 11.1 5.7 3.4 4.8 4.5 4.6 5.6 3.6 PRADC1 "C2orf7, hPAP21, MGC13004, PAP21" ENSG00000135617 "Protease associated domain containing 1" Q9BSG0 2 73228010-73233239 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.6" "Cell type enhanced" "Detected in all" "Late spermatids: 144.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051066 Approved "Secreted to blood" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA051066: AB_2681333" "unprognostic (2.94e-1)" "unprognostic (1.93e-2)" "unprognostic (1.22e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (3.93e-2)" "unprognostic (8.54e-2)" "unprognostic (9.08e-3)" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (1.09e-3)" "unprognostic (9.99e-3)" "unprognostic (3.56e-2)" "unprognostic (2.96e-1)" "unprognostic (4.89e-1)" "unprognostic (1.93e-1)" "unprognostic (9.23e-2)" 22.8 35.9 46.0 9.8 48.1 8.7 19.3 48.6 50.6 15.1 54.1 29.0 25.2 12.6 16.3 25.8 11.3 9.8 101.4 45.8 46.9 27.0 71.5 12.7 9.2 47.6 47.3 11.0 41.6 21.2 23.1 8.2 47.4 19.3 21.4 15.5 29.1 14.7 126.6 20.6 22.1 14.8 46.7 23.6 27.1 31.3 49.0 11.0 17.9 107.1 9.9 23.1 16.3 46.4 21.7 16.6 16.2 31.3 49.3 19.2 22.6 37.8 15.1 32.5 18.7 46.6 20.6 23.3 20.2 38.0 29.3 19.5 25.8 22.7 23.0 36.2 28.2 36.7 21.4 35.2 15.3 20.3 33.7 25.0 13.5 29.2 15.4 9.4 30.5 39.0 32.4 46.1 37.8 41.9 51.7 34.0 5.2 93.7 74.2 31.0 68.6 71.8 18.6 19.0 34.5 12.3 18.1 42.5 15.7 17.3 22.5 15.7 18.9 37.6 16.6 32.9 31.8 52.2 43.9 22.3 24.0 39.6 15.7 15.6 35.0 35.4 24.8 84.3 20.1 17.5 23.8 23.6 36.3 21.8 22.3 19.5 5.0 39.2 105.3 73.3 31.1 48.2 46.0 48.1 48.6 50.6 45.8 46.9 47.6 47.3 47.4 46.7 49.0 46.4 21.7 9.6 4.6 10.1 11.0 15.6 11.3 34.5 4.6 15.2 23.3 23.9 62.6 15.7 20.0 14.7 8.4 25.7 25.4 44.7 72.4 23.3 57.3 12.1 9.3 17.7 32.3 4.2 6.9 46.9 47.2 20.4 13.7 6.0 28.6 4.8 30.7 63.0 49.1 11.8 6.9 47.7 44.7 25.5 14.0 144.3 16.8 19.3 16.0 1.9 7.2 31.4 21.6 6.0 7.0 23.2 31.2 16.1 29.2 10.7 101.4 65.2 15.8 28.3 32.9 19.1 19.1 61.5 21.1 30.1 24.0 13.5 9.7 27.2 50.2 15.4 CCT7 "Ccth, Nip7-1" ENSG00000135624 "Chaperonin containing TCP1 subunit 7" Q99832 2 73233420-73253021 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 393.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008425 Approved Approved Cytosol NA NA 1900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "HPA008425: AB_1078428" "unprognostic (5.02e-3)" "unprognostic (9.51e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (4.60e-2)" "unprognostic (1.37e-2)" "prognostic unfavorable (1.84e-5)" "unprognostic (4.37e-3)" "unprognostic (8.76e-2)" "unprognostic (3.17e-1)" "unprognostic (4.24e-2)" "unprognostic (3.78e-1)" "unprognostic (1.41e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (3.07e-3)" "unprognostic (3.12e-2)" 113.3 150.8 104.5 108.6 109.7 93.4 111.4 114.6 110.9 109.6 118.1 113.6 84.8 123.0 117.1 119.7 133.3 69.0 162.9 109.1 114.5 111.9 114.0 83.4 126.5 109.7 109.4 140.4 114.2 134.7 97.0 101.4 114.0 115.2 123.2 83.7 92.1 110.7 252.4 103.9 88.3 147.5 112.7 98.7 106.8 162.9 110.7 153.0 87.4 241.2 158.5 120.0 101.1 120.7 396.3 641.9 361.8 393.0 259.1 211.7 460.7 348.6 311.8 573.6 359.0 1054.5 272.1 760.3 219.0 365.9 529.3 328.2 816.6 533.8 635.9 420.7 722.9 516.2 403.2 755.3 287.5 614.9 367.5 328.9 297.7 565.9 683.3 301.4 521.0 444.7 650.2 265.8 488.7 613.6 686.5 776.1 519.1 540.6 455.8 614.8 927.2 535.0 411.6 374.7 512.4 315.9 302.6 411.0 406.7 333.6 235.2 331.4 339.7 390.9 464.3 245.7 679.7 298.1 341.1 709.2 319.4 686.1 435.6 157.7 131.4 78.1 190.8 178.8 211.3 216.6 193.5 191.4 202.0 208.8 208.9 195.3 39.5 192.1 209.8 203.7 186.0 299.3 104.5 109.7 114.6 110.9 109.1 114.5 109.7 109.4 114.0 112.7 110.7 120.7 77.7 57.7 45.6 12.4 87.5 69.1 149.7 161.5 55.8 81.1 63.8 77.1 99.2 68.6 96.7 58.8 18.8 190.2 74.3 54.8 109.5 148.2 393.0 99.8 96.4 91.6 75.3 77.8 10.8 139.0 213.2 94.8 57.1 58.1 73.6 108.2 61.8 69.3 133.6 82.4 13.3 102.2 118.0 58.8 58.1 246.3 104.7 57.3 74.7 10.3 98.9 125.5 74.2 12.1 15.0 134.1 60.3 107.2 112.3 156.0 67.3 133.2 108.2 88.6 72.3 91.8 126.7 288.9 127.8 71.1 73.6 166.5 77.2 190.6 127.6 112.5 FBXO41 "Fbx41, KIAA1940" ENSG00000163013 "F-box protein 41" Q8TF61 2 73254682-73284478 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.9;Enteroendocrine cells: 12.0;Excitatory neurons: 28.8;Inhibitory neurons: 22.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 21.2;basal ganglia: 31.0;cerebral cortex: 42.3;hippocampal formation: 29.6;white matter: 24.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055246, HPA058386" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA055246: AB_2682758, HPA058386: AB_2683701" "unprognostic (1.15e-3)" "unprognostic (9.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.74e-2)" "unprognostic (5.85e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-1)" "unprognostic (7.97e-3)" "unprognostic (7.55e-2)" "unprognostic (9.13e-3)" "unprognostic (4.35e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-2)" 1.3 3.0 21.2 4.6 31.0 3.3 1.5 7.2 42.3 1.7 0.0 1.8 1.4 1.6 2.3 1.3 1.7 1.7 1.0 29.6 4.6 1.1 0.4 1.5 7.7 4.2 3.8 2.5 3.7 5.5 13.9 0.5 4.6 2.6 1.4 3.1 2.6 2.0 0.1 2.3 5.3 1.2 1.1 9.1 1.8 2.3 5.4 5.5 1.2 0.1 6.9 1.5 1.4 24.8 6.4 3.1 1.0 0.0 0.3 0.2 1.4 1.2 1.0 2.0 2.5 7.2 3.6 46.6 0.2 0.2 4.5 5.1 6.5 4.1 2.0 19.4 0.6 14.5 8.0 3.0 1.5 22.2 10.4 2.5 1.6 0.1 1.6 5.6 0.3 12.7 2.9 7.6 2.1 1.7 7.7 20.4 4.7 2.4 2.7 25.4 11.7 23.2 1.3 2.2 15.7 5.8 8.0 3.3 5.0 0.3 4.5 9.2 0.4 7.0 5.9 6.4 1.2 8.5 3.9 22.1 1.8 23.7 3.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 21.2 31.0 7.2 42.3 29.6 4.6 4.2 3.8 4.6 1.1 5.4 24.8 0.3 0.0 0.6 2.6 5.1 0.3 0.3 1.0 1.2 13.9 1.8 1.4 2.1 1.5 0.3 1.8 0.0 0.0 3.4 0.5 0.0 0.5 0.2 0.3 2.5 0.4 12.0 0.0 28.8 2.5 0.1 2.1 0.0 1.1 2.5 2.1 0.7 0.0 1.9 6.7 22.4 0.4 2.0 4.7 1.1 1.5 0.3 3.2 1.8 7.5 2.6 0.9 2.1 5.5 0.9 1.1 0.3 0.7 3.6 0.8 0.1 0.3 1.1 2.3 0.0 0.3 0.7 1.3 2.4 0.5 0.3 0.0 3.1 5.4 0.8 0.2 EGR4 "NGFI-C, PAT133" ENSG00000135625 "Early growth response 4" Q05215 2 73290929-73293701 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 54.0" "Cell type enriched" "Detected in many" 6 "Enteroendocrine cells: 99.5" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 6 "cerebellum: 31.4;cerebral cortex: 54.0;hippocampal formation: 22.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "HMC-1: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028983 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA028983: AB_10603665" "unprognostic (7.75e-2)" "unprognostic (1.17e-1)" "unprognostic (1.39e-4)" "unprognostic (2.43e-3)" "unprognostic (2.68e-2)" "unprognostic (8.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (5.20e-2)" "unprognostic (4.00e-1)" "unprognostic (2.29e-4)" "unprognostic (2.41e-1)" "unprognostic (1.75e-2)" "unprognostic (3.20e-2)" "unprognostic (1.77e-1)" "unprognostic (1.21e-2)" "unprognostic (4.07e-3)" 0.2 0.1 2.6 0.1 5.5 0.1 0.0 31.4 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 22.1 1.6 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 3.4 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 5.5 31.4 54.0 22.1 1.6 0.0 2.4 2.4 0.0 1.5 2.6 1.3 0.0 0.0 0.0 2.6 2.7 13.2 0.6 0.6 3.0 6.8 7.2 1.2 0.0 0.2 0.0 0.0 0.1 5.0 0.4 0.0 0.2 0.0 2.9 7.0 1.0 99.5 0.0 3.8 1.0 0.3 0.7 5.1 15.9 8.9 16.1 0.0 0.0 0.2 0.0 0.5 0.6 2.0 0.6 5.3 0.6 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 1.1 0.0 1.0 10.8 0.0 0.0 0.1 0.8 0.0 0.2 5.7 0.2 13.2 1.7 2.3 0.8 1.5 3.4 0.8 0.2 ALMS1 KIAA0328 ENSG00000116127 "ALMS1 centrosome and basal body associated protein" Q8TCU4 2 73385758-73625166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Cone-rod dystrophy, Deafness, Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 68.4;Excitatory neurons: 64.9;Late spermatids: 86.6;Oligodendrocytes: 92.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 32.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035277, HPA043200" Enhanced Approved "Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles, Centrosome" Cytosol "HPA035277: , HPA043200: AB_10796689" "unprognostic (2.86e-1)" "unprognostic (9.67e-2)" "unprognostic (2.58e-2)" "unprognostic (4.50e-3)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (2.91e-3)" "unprognostic (7.73e-2)" "unprognostic (1.02e-1)" "unprognostic (8.58e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (3.43e-2)" "unprognostic (1.63e-1)" "unprognostic (7.85e-2)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" 2.6 2.4 5.3 2.4 6.8 5.5 4.3 16.0 5.2 4.1 4.5 3.1 2.3 4.5 4.7 1.9 6.4 2.5 1.6 5.3 4.8 3.5 2.4 3.1 3.2 6.8 6.4 9.8 4.5 4.8 1.7 2.7 6.0 3.5 3.0 10.4 2.9 3.6 0.8 2.9 1.9 3.6 5.1 2.4 2.9 22.2 5.7 8.7 4.6 3.1 2.9 2.6 1.5 7.8 14.3 4.6 9.0 8.2 6.2 5.8 6.7 4.8 5.0 6.2 4.8 4.8 1.5 13.8 3.3 6.7 8.0 6.5 12.3 4.2 8.3 6.7 4.1 7.9 4.4 10.2 4.1 10.9 3.8 4.5 3.7 7.6 3.9 3.9 6.3 9.3 7.4 4.9 7.1 7.0 10.2 14.3 10.6 5.7 3.9 10.8 32.5 5.1 4.1 3.7 7.1 10.0 9.1 1.5 5.2 7.5 1.7 2.5 5.4 8.2 8.3 7.1 11.7 6.6 4.0 10.4 3.7 8.2 4.0 0.2 0.0 0.5 0.2 0.1 0.1 0.2 0.3 0.2 0.0 0.2 0.2 0.3 0.0 0.2 0.1 0.3 0.2 0.0 5.3 6.8 16.0 5.2 5.3 4.8 6.8 6.4 6.0 5.1 5.7 7.8 7.3 6.4 10.3 48.3 5.6 2.4 3.1 2.6 6.8 23.3 4.7 4.8 7.2 7.2 9.1 11.0 25.0 3.3 12.8 4.4 0.0 4.7 68.4 30.6 13.2 8.0 7.3 15.4 64.9 3.7 2.7 8.9 10.7 9.3 5.1 21.8 4.6 2.2 3.3 21.9 55.8 5.2 0.0 3.1 2.7 86.6 8.1 6.3 3.6 31.9 5.3 9.2 5.2 54.3 92.7 3.4 1.3 9.1 10.2 3.2 4.0 1.7 25.2 39.7 6.6 14.8 9.5 30.6 26.7 6.9 3.3 1.9 7.8 11.5 5.3 2.0 NAT8 "ATase2, GLA, Hcml1, TSC501" ENSG00000144035 "N-acetyltransferase 8 (putative)" Q9UHE5 2 73640723-73642422 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "kidney: 732.4" "Cell type enriched" "Detected in some" 13 "Proximal tubular cells: 2565.5" "Cancer enriched" "Detected in some" 5 "renal cancer: 242.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "Hep G2: 10.7" "Low region specificity" "Detected in all" "HPA067855, HPA074519" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum" "HPA067855: AB_2732774, HPA074519: AB_2686699" "unprognostic (4.51e-2)" "unprognostic (6.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (1.90e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (8.60e-2)" "unprognostic (1.37e-3)" "unprognostic (2.07e-2)" "unprognostic (4.11e-3)" "unprognostic (2.13e-2)" "unprognostic (8.36e-5)" 0.1 0.3 1.1 0.1 0.5 0.1 0.2 0.1 0.7 0.2 0.0 1.1 4.6 0.1 0.0 0.0 1.2 0.6 0.1 0.8 0.8 732.4 82.7 0.2 0.0 0.6 0.3 1.3 0.2 0.0 0.6 0.0 0.1 0.2 0.1 1.8 0.1 0.1 0.0 0.0 7.2 0.1 0.4 1.1 0.6 0.5 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.1 0.7 0.8 0.8 0.6 0.3 0.1 0.4 1.0 0.8 0.0 0.0 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 36.8 0.0 0.0 0.0 0.3 187.9 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 22.9 51.1 0.0 0.0 0.0 1.1 0.0 1.0 0.4 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 61.3 2565.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.6 0.1 TPRKB "CGI-121, CGI121" ENSG00000144034 "TP53RK binding protein" Q9Y3C4 2 73729104-73737400 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "tRNA processing" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035712 Approved Supported Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA035712: AB_10669674" "unprognostic (1.11e-1)" "unprognostic (2.41e-2)" "unprognostic (6.59e-2)" "unprognostic (2.31e-2)" "unprognostic (2.74e-1)" "unprognostic (2.67e-2)" "unprognostic (1.21e-3)" "unprognostic (4.96e-2)" "unprognostic (3.16e-3)" "unprognostic (3.01e-3)" "unprognostic (5.10e-3)" "unprognostic (6.06e-2)" "unprognostic (2.68e-3)" "unprognostic (5.66e-2)" "unprognostic (8.45e-3)" "unprognostic (1.82e-1)" "unprognostic (5.03e-2)" 22.7 23.1 11.8 22.3 12.3 70.2 42.7 14.5 17.2 32.7 12.6 36.5 38.7 30.2 35.8 31.0 54.9 20.2 34.0 12.0 12.5 35.5 39.2 17.3 37.0 12.7 12.2 36.1 26.7 18.5 12.7 22.6 12.7 25.0 33.9 16.1 31.1 19.0 68.1 25.7 35.5 29.1 12.7 22.3 24.9 51.8 12.1 37.0 21.3 50.9 33.7 26.3 25.2 13.1 106.1 73.3 73.4 85.5 27.2 37.6 62.2 73.5 40.0 72.2 54.2 110.8 66.0 67.0 54.0 38.2 130.7 62.6 60.6 77.6 116.0 53.4 79.2 135.7 49.8 90.6 26.6 198.3 72.8 27.2 43.6 76.4 76.3 37.4 76.9 114.7 119.8 105.1 75.5 56.4 142.5 130.6 94.9 130.5 93.9 83.6 211.6 93.8 67.2 89.8 69.1 83.1 53.1 79.5 105.6 59.8 58.7 78.6 48.5 62.4 104.7 113.6 182.6 69.1 127.6 176.9 55.9 131.2 78.4 32.5 18.2 29.1 16.5 28.5 26.4 23.9 23.6 22.3 22.1 20.9 27.0 25.5 13.1 24.6 21.5 30.1 25.4 15.8 11.8 12.3 14.5 17.2 12.0 12.5 12.7 12.2 12.7 12.7 12.1 13.1 56.3 32.1 39.8 7.2 43.1 53.2 66.8 123.0 38.7 15.0 51.8 94.9 63.5 50.1 70.6 22.0 4.2 81.3 39.7 64.0 88.0 95.4 138.9 50.2 42.7 81.9 33.6 62.1 8.6 184.9 107.9 45.1 17.9 43.4 48.7 51.3 148.2 44.3 86.7 8.4 8.7 71.2 71.2 55.6 60.0 28.9 59.0 52.1 33.8 2.8 65.0 36.6 64.9 10.1 8.3 110.7 76.9 52.3 35.6 47.8 103.4 154.9 54.4 21.8 52.6 61.7 46.2 259.3 87.8 44.8 53.0 45.6 42.8 53.9 85.4 58.2 DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73762184-73780157 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: AB_2670577" "unprognostic (2.45e-3)" "unprognostic (1.06e-1)" "unprognostic (2.19e-2)" "unprognostic (7.87e-3)" "unprognostic (9.14e-2)" "unprognostic (5.28e-3)" "prognostic unfavorable (2.10e-7)" "unprognostic (7.20e-2)" "unprognostic (5.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.67e-3)" "unprognostic (3.84e-2)" "unprognostic (7.56e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-3)" "unprognostic (1.46e-1)" 16.0 13.3 7.9 17.1 7.7 35.2 20.4 13.4 11.2 22.4 7.6 16.0 17.3 21.2 19.3 30.5 39.0 15.9 14.2 8.1 6.9 20.2 17.9 14.3 25.3 6.1 5.7 23.5 11.0 14.7 14.0 20.5 6.1 16.5 17.4 8.3 16.0 14.4 14.3 27.6 15.3 19.6 4.8 19.0 16.3 16.8 6.5 24.8 16.5 17.8 26.1 25.2 22.4 8.3 39.4 16.7 17.6 18.6 31.2 38.7 31.2 28.2 36.7 35.8 36.4 24.2 29.1 50.6 17.7 30.6 32.1 26.7 22.0 56.8 34.3 35.2 22.9 31.2 12.0 37.3 32.7 35.5 28.0 31.6 67.3 32.1 44.1 31.1 40.4 24.2 33.6 28.6 40.2 21.3 34.3 37.6 28.4 36.7 22.7 13.6 47.3 46.0 29.3 32.1 25.9 14.1 26.1 30.6 35.7 21.0 16.4 18.6 23.1 25.4 31.4 29.5 33.7 30.7 26.2 68.1 23.5 35.5 25.3 72.5 42.2 99.5 56.3 39.3 73.5 68.3 65.8 67.4 47.3 65.9 69.4 65.5 65.2 69.8 40.6 35.7 88.6 71.7 7.9 7.7 13.4 11.2 8.1 6.9 6.1 5.7 6.1 4.8 6.5 8.3 26.5 9.6 12.0 7.5 39.5 83.2 55.1 93.0 39.3 11.0 12.9 15.1 8.6 27.1 45.7 12.9 4.2 32.8 34.8 15.5 50.9 29.6 9.1 18.0 15.7 34.6 12.0 21.0 14.9 27.3 42.0 26.5 16.3 13.6 40.7 20.5 52.1 15.3 30.7 5.0 12.7 18.0 36.7 20.2 27.1 7.0 28.9 17.0 23.2 10.3 34.8 9.8 41.2 13.0 13.8 28.2 17.8 25.6 31.8 30.0 22.8 50.4 38.2 16.6 6.6 18.2 23.1 23.8 34.6 42.8 83.0 38.6 39.8 20.7 18.8 60.9 C2orf78 "COG5373, FLJ43987, hCG1989538" ENSG00000187833 "Chromosome 2 open reading frame 78" A6NCI8 2 73784189-73817147 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 23 "testis: 12.4" "Cell type enriched" "Detected in some" 5 "Early spermatids: 49.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (5.25e-2)" "unprognostic (6.56e-3)" "unprognostic (2.42e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 1108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 15.6 11.6 21.7 14.6 30.6 13.3 20.2 29.7 23.8 19.3 19.3 21.5 20.7 20.6 15.5 25.4 18.3 16.9 22.3 20.6 24.5 21.9 19.0 15.7 19.3 31.3 28.0 17.7 12.2 24.3 9.3 17.3 30.4 22.1 23.2 14.6 21.5 15.6 37.4 16.7 20.4 21.3 27.9 14.9 18.2 15.8 27.1 23.2 22.6 42.8 21.6 16.8 16.0 38.6 39.0 44.0 34.0 31.6 31.1 37.2 39.1 23.3 31.7 42.1 40.3 73.7 35.9 32.2 35.8 19.8 55.7 30.0 36.6 81.7 47.6 56.6 41.3 43.3 29.1 58.1 43.4 35.8 50.0 30.1 57.6 49.6 70.7 53.5 25.1 43.7 47.9 47.8 1108.9 46.8 55.9 32.4 54.9 55.1 22.7 38.6 89.4 46.1 45.2 43.0 62.0 45.8 28.4 34.6 49.1 36.4 32.3 21.4 22.0 37.5 44.5 22.9 41.9 44.8 46.9 24.9 46.4 38.1 44.7 30.7 18.9 34.2 15.9 21.4 17.2 21.5 18.3 15.6 19.9 19.3 18.9 14.4 27.6 22.3 19.9 19.5 25.8 14.9 21.7 30.6 29.7 23.8 20.6 24.5 31.3 28.0 30.4 27.9 27.1 38.6 22.1 19.2 17.7 22.9 21.5 16.3 28.9 61.7 31.3 22.3 28.8 27.7 41.1 28.6 34.4 25.8 12.5 43.0 27.4 48.7 49.0 37.9 80.8 35.6 37.3 21.4 10.3 34.9 18.5 36.3 32.5 26.0 18.8 45.8 52.6 21.2 17.5 41.1 33.0 26.9 22.1 36.4 40.7 27.7 16.2 125.0 32.6 25.2 7.2 16.9 34.1 24.9 25.7 26.2 67.2 44.5 41.8 34.6 21.5 40.9 57.2 68.8 24.5 21.0 39.5 28.2 27.2 33.1 44.2 44.5 21.6 44.5 21.4 27.5 34.3 27.1 ACTG2 "ACTA3, ACTL3, ACTSG" ENSG00000163017 "Actin gamma 2, smooth muscle" P63267 2 73892314-73919865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8846.3;seminal vesicle: 6238.4;smooth muscle: 8607.9" "Group enriched" "Detected in many" 4 "Breast myoepithelial cells: 394.2;Smooth muscle cells: 287.8" "Cancer enhanced" "Detected in all" "prostate cancer: 255.0;stomach cancer: 237.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "T-reg: 8.6" "Lineage enriched" "Detected in single" 17 "T-cells: 8.6" "Cell line enhanced" "Detected in many" "BEWO: 63.8;BJ hTERT+: 53.5;BJ hTERT+ SV40 Large T+: 214.8;HHSteC: 55.1;SuSa: 52.5;U-251 MG: 229.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 11.8;spinal cord: 4.7" "HPA041264, HPA041271" Supported NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA041264: AB_2677383, HPA041271: AB_2677386" "unprognostic (5.79e-3)" "unprognostic (2.25e-1)" "unprognostic (2.36e-2)" "unprognostic (2.91e-1)" "unprognostic (4.56e-3)" "unprognostic (2.50e-1)" "unprognostic (8.05e-2)" "unprognostic (6.53e-2)" "unprognostic (4.48e-2)" "unprognostic (2.93e-1)" "unprognostic (7.23e-2)" "unprognostic (4.75e-2)" "prognostic unfavorable (3.95e-7)" "unprognostic (9.30e-3)" "unprognostic (6.84e-2)" "unprognostic (2.29e-2)" "unprognostic (7.57e-3)" 189.6 37.1 2.8 724.8 3.9 0.0 138.2 2.8 10.0 494.7 4.8 8846.3 392.1 3622.6 124.6 1954.7 857.3 330.4 30.4 2.9 2.9 11.3 10.8 137.5 6.8 3.4 3.1 88.5 8.1 0.9 6.1 96.4 3.1 2250.2 1179.0 0.0 75.1 6238.4 16.3 91.8 1353.8 8607.9 2.9 16.6 2099.7 4.8 3.1 2.8 33.8 6.9 1.2 2914.5 667.3 2.8 0.7 0.3 20.5 0.3 0.0 0.0 63.8 13.5 53.5 214.8 38.6 6.7 0.0 0.3 0.9 0.0 0.4 0.1 36.9 0.0 28.3 0.1 0.0 0.0 2.9 0.5 55.1 0.2 0.6 0.5 0.3 29.0 0.0 1.5 0.0 0.2 0.0 0.0 0.5 0.0 2.9 7.9 0.2 0.0 0.1 0.2 0.4 3.1 0.5 13.6 0.6 2.3 0.3 2.8 1.2 52.5 0.0 0.3 0.0 1.1 2.3 2.5 229.9 0.1 0.3 0.8 0.7 1.0 0.9 0.2 0.5 0.3 0.2 0.3 0.1 0.1 0.8 0.3 0.4 0.1 0.4 0.5 0.1 0.2 0.4 0.1 8.6 2.4 2.8 3.9 2.8 10.0 2.9 2.9 3.4 3.1 3.1 2.9 3.1 2.8 3.5 0.0 0.5 0.0 0.4 4.5 2.7 0.5 0.6 0.0 9.8 394.2 14.6 0.0 0.1 0.0 0.0 7.4 0.7 0.0 0.0 0.0 5.8 2.8 1.5 3.1 0.0 0.0 0.1 0.0 36.8 74.1 0.0 4.8 0.0 1.0 22.9 0.3 5.4 0.0 0.1 0.0 0.0 0.0 10.4 26.6 0.3 1.0 7.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 10.8 0.0 0.4 0.8 0.0 6.6 1.8 287.8 0.2 3.2 0.4 7.7 6.4 1.7 8.4 0.0 3.7 DGUOK dGK ENSG00000114956 "Deoxyguanosine kinase" Q16854 2 73926826-73958961 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034766, HPA057246" Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA034766: AB_10669850, HPA057246: AB_2683381" "unprognostic (3.40e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.94e-2)" "unprognostic (1.20e-1)" "unprognostic (4.17e-2)" "unprognostic (2.14e-2)" "unprognostic (1.37e-2)" "unprognostic (4.10e-3)" "unprognostic (5.07e-2)" "unprognostic (1.41e-1)" "unprognostic (9.84e-2)" "prognostic unfavorable (8.69e-7)" "unprognostic (3.86e-1)" "unprognostic (2.21e-2)" "unprognostic (5.98e-2)" "prognostic favorable (7.47e-4)" 20.8 30.0 37.1 20.3 39.2 27.1 28.1 36.5 48.4 23.0 36.8 25.0 17.7 23.1 34.4 21.8 31.3 19.4 23.0 38.5 42.8 24.6 30.5 17.7 36.8 37.9 37.7 30.0 16.3 11.0 41.3 21.5 39.1 24.5 29.1 34.5 19.8 22.5 17.1 26.5 20.2 21.9 37.9 25.9 21.0 32.8 38.8 36.3 22.6 17.7 40.9 22.2 20.9 38.8 45.1 72.5 74.4 67.9 47.8 53.8 37.1 29.3 56.0 66.7 61.1 91.2 51.5 83.0 27.4 42.1 74.1 34.7 85.4 57.1 79.3 47.1 53.6 65.8 25.4 107.5 70.5 62.1 66.0 49.7 51.3 50.4 58.9 48.6 48.3 91.4 67.2 37.0 78.8 54.4 59.6 101.2 76.7 60.5 53.9 73.8 73.1 59.7 55.8 49.6 85.0 82.6 27.9 28.2 77.1 35.5 34.0 34.8 45.3 43.3 68.8 37.8 52.6 32.3 31.4 86.1 62.2 65.9 95.1 129.8 70.9 138.7 62.3 87.3 72.4 108.5 77.0 69.6 81.6 114.5 98.6 79.6 56.4 79.4 84.7 91.3 79.9 91.3 37.1 39.2 36.5 48.4 38.5 42.8 37.9 37.7 39.1 37.9 38.8 38.8 72.5 32.1 42.8 14.7 103.4 74.2 138.7 249.6 88.2 52.3 85.0 128.1 19.1 78.6 108.6 60.7 6.2 159.4 89.7 58.9 84.1 102.6 12.3 82.3 69.1 74.1 113.1 67.1 17.5 149.1 165.4 88.3 40.2 82.6 57.6 87.4 76.1 69.9 90.9 52.2 21.1 100.1 158.7 88.3 112.3 15.1 93.5 80.2 110.3 15.9 151.9 89.5 118.4 12.5 27.2 173.0 88.1 86.9 70.2 146.2 88.2 119.7 87.2 40.4 92.1 55.3 89.3 105.3 129.4 88.3 83.3 124.5 101.4 124.5 104.9 142.9 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.2 1.6 3.7 5.2 2.4 19.7 3.0 6.3 13.7 2.5 0.0 4.1 5.4 2.0 1.4 7.6 1.9 2.5 1.2 9.3 1.7 1.6 3.9 4.1 3.7 2.0 1.5 1.5 2.6 2.0 1.5 4.6 2.2 2.5 4.3 3.6 4.2 1.1 1.2 16.2 6.0 2.1 0.6 3.8 4.3 1.6 2.7 5.8 2.3 1.3 4.1 3.4 4.0 5.8 9.0 8.0 14.5 8.9 1.2 1.3 26.4 1.8 2.4 3.4 2.7 16.6 8.1 14.9 3.5 2.4 1.6 9.4 13.0 5.2 3.6 6.7 5.2 19.2 7.0 5.6 5.1 20.2 11.3 2.0 13.3 4.2 9.9 4.3 5.3 10.3 13.4 4.8 2.0 14.6 10.0 13.0 8.1 7.7 2.7 15.4 9.1 5.2 3.8 16.5 18.1 15.5 4.0 10.3 4.9 5.7 6.6 16.1 6.7 3.7 15.4 1.8 6.8 4.2 2.0 12.7 2.4 13.9 4.9 0.1 0.4 0.2 0.0 0.4 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.2 3.7 2.4 6.3 13.7 9.3 1.7 2.0 1.5 2.2 0.6 2.7 5.8 4.2 6.4 9.0 31.3 6.4 49.5 3.5 4.2 14.8 16.3 8.0 5.8 2.9 2.8 8.0 1.8 20.9 7.0 7.3 10.5 0.0 3.5 4.7 18.8 11.9 6.6 6.0 24.8 88.5 4.4 30.1 3.4 13.7 29.6 2.5 6.2 3.6 6.1 10.1 10.1 45.7 8.0 8.2 26.9 23.2 0.8 0.6 26.9 10.6 54.4 27.1 1.5 2.1 41.7 86.7 6.2 7.7 3.0 4.8 6.2 10.3 1.5 11.9 8.6 0.0 3.8 7.7 0.5 2.6 24.4 68.2 2.5 5.5 2.3 6.9 7.0 BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 173.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 313.2;Distal tubular cells: 352.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: AB_2682063" "unprognostic (1.38e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-2)" "unprognostic (4.23e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.86e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (4.03e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (9.90e-5)" "unprognostic (1.19e-1)" "unprognostic (1.92e-1)" "unprognostic (1.33e-1)" "unprognostic (4.40e-1)" 35.6 39.3 52.1 22.6 54.3 40.8 31.4 58.9 66.1 20.2 55.0 46.5 33.8 24.5 25.1 31.7 20.8 11.9 101.0 52.7 56.5 59.8 33.7 23.5 22.2 57.0 53.8 16.6 44.7 56.2 29.6 14.2 56.0 25.4 37.6 35.7 39.7 23.7 117.8 16.6 28.9 22.6 54.7 21.9 41.1 15.8 53.7 24.8 28.8 173.9 21.6 27.1 24.3 55.3 102.8 134.0 44.8 46.2 81.5 78.3 113.9 92.5 54.5 104.0 72.0 176.6 45.4 67.2 79.7 82.4 99.3 53.2 107.9 135.4 95.8 126.5 172.8 85.4 88.3 269.8 76.1 167.3 39.0 62.2 96.6 100.9 124.2 45.9 79.4 144.3 183.2 73.7 116.0 163.6 136.4 123.1 66.9 196.8 198.6 88.5 120.1 132.0 138.8 106.2 70.4 40.7 68.3 106.8 123.3 62.0 62.6 102.8 42.6 83.9 142.9 93.8 185.4 67.5 135.3 92.7 87.6 131.8 73.8 14.7 14.2 3.9 68.3 29.9 75.7 45.4 92.7 72.6 37.8 44.5 79.3 68.7 3.0 51.7 33.5 65.1 91.2 40.6 52.1 54.3 58.9 66.1 52.7 56.5 57.0 53.8 56.0 54.7 53.7 55.3 54.7 9.6 29.8 8.5 33.2 22.7 44.5 111.8 43.3 29.9 82.0 109.5 313.2 44.3 50.1 84.6 16.7 54.9 42.8 125.4 352.1 93.2 20.0 67.0 46.2 45.5 76.1 138.2 14.3 111.4 167.5 48.6 58.1 61.5 25.4 31.9 36.4 113.3 113.9 26.9 15.0 128.3 83.4 32.1 28.9 10.2 32.9 32.2 99.6 3.7 59.4 61.8 62.8 7.5 7.7 95.0 70.9 46.3 76.1 50.9 85.6 266.4 51.2 52.6 19.7 39.6 64.4 66.8 80.5 101.0 16.9 22.3 45.1 83.0 176.2 52.0 MOB1A "C2orf6, FLJ10788, FLJ11595, Mats1, MOB1, Mob4B, MOBK1B, MOBKL1B" ENSG00000114978 "MOB kinase activator 1A" Q9H8S9 2 74152528-74178898 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047088, HPA071690" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Nucleoli" "HPA047088: AB_2679927, HPA071690: AB_2686432" "unprognostic (5.32e-2)" "unprognostic (2.45e-1)" "unprognostic (5.38e-2)" "unprognostic (2.62e-1)" "unprognostic (2.19e-1)" "unprognostic (8.19e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (9.36e-2)" "unprognostic (3.91e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-3)" "unprognostic (1.04e-1)" "unprognostic (2.20e-3)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (1.10e-1)" "unprognostic (5.11e-3)" 36.6 24.7 12.6 64.2 11.8 90.5 31.4 12.9 13.5 36.4 18.6 41.0 42.3 35.0 25.5 40.2 33.2 35.5 25.3 11.4 15.6 48.1 30.7 38.9 91.9 15.8 13.6 31.9 16.0 28.6 9.1 35.8 16.7 30.3 42.7 10.2 19.5 29.4 13.2 38.9 41.7 40.5 15.8 61.1 34.2 19.8 12.8 56.1 33.6 19.4 93.1 46.6 26.0 17.9 78.2 43.9 53.9 58.5 86.9 94.0 63.5 61.3 82.0 78.1 76.6 60.2 55.4 159.0 51.3 77.4 58.2 63.7 69.6 70.2 117.7 113.0 41.5 143.7 28.0 64.3 69.1 126.1 222.1 80.2 67.1 62.6 52.5 58.6 83.3 60.4 62.5 57.2 76.8 42.1 159.4 106.9 50.3 66.4 35.6 108.2 185.2 85.2 67.3 96.1 27.3 35.6 87.1 63.6 56.4 40.4 51.0 59.1 79.6 100.9 53.0 71.4 98.7 42.2 40.5 119.5 68.0 105.3 55.3 103.7 65.3 91.5 37.3 106.1 40.3 57.8 33.3 40.3 60.5 46.1 30.2 36.4 65.6 56.4 126.0 42.1 37.2 79.7 12.6 11.8 12.9 13.5 11.4 15.6 15.8 13.6 16.7 15.8 12.8 17.9 82.6 51.3 58.0 3.9 173.0 136.9 96.5 107.4 60.9 13.3 66.8 45.1 40.0 35.8 79.5 82.8 6.2 63.8 170.1 114.1 92.0 60.9 11.1 88.3 91.3 73.1 37.7 48.8 7.4 52.6 101.9 67.2 55.0 102.2 110.4 58.5 61.1 43.0 169.5 26.9 7.9 67.4 65.1 196.6 246.9 11.8 62.4 226.1 67.6 14.0 350.8 25.2 117.4 6.0 10.1 83.4 85.7 68.4 106.4 127.8 80.4 170.2 116.6 14.5 72.3 60.6 75.3 99.5 44.6 86.6 132.0 66.4 124.4 79.3 74.0 155.3 MTHFD2 ENSG00000065911 "Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase" P13995 2 74186172-74217565 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Hydrolase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 243.6;monocytes: 184.1;Smooth muscle cells: 239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003684, HPA049657" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 48: Smooth muscle cells - ECM organization" Mitochondria "CAB003684: AB_425867, HPA049657: AB_2680842" "unprognostic (1.82e-3)" "unprognostic (4.60e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.07e-5)" "prognostic favorable (1.01e-4)" "unprognostic (3.10e-3)" "unprognostic (2.24e-3)" "unprognostic (4.75e-3)" "unprognostic (2.64e-2)" "unprognostic (3.96e-2)" "unprognostic (3.76e-3)" "unprognostic (3.57e-3)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.66e-2)" "unprognostic (6.52e-2)" "unprognostic (9.07e-2)" "unprognostic (2.34e-3)" 40.0 12.3 11.2 54.5 13.0 25.8 34.8 12.7 14.7 28.5 11.2 30.6 18.6 21.5 14.5 23.0 34.2 20.1 19.6 10.0 16.6 19.6 7.3 23.0 45.6 16.6 15.8 11.7 65.9 9.8 18.0 17.7 17.1 16.3 33.7 2.9 17.7 16.7 36.7 11.8 16.0 27.3 14.8 19.0 36.1 17.7 13.1 28.5 18.5 55.3 57.8 48.0 20.5 15.7 197.4 107.8 89.2 235.6 90.0 113.9 186.1 286.2 185.2 156.2 216.7 242.8 81.8 391.0 65.4 154.2 167.5 70.7 296.7 142.0 314.9 248.9 100.9 424.6 55.4 181.9 319.8 360.1 234.8 202.9 423.4 188.5 794.4 74.8 99.0 636.5 192.2 548.0 157.5 159.6 209.5 261.0 161.1 293.3 95.8 222.6 266.3 339.4 72.0 80.8 198.2 143.8 97.4 238.3 549.7 56.9 208.5 324.4 52.9 39.1 359.9 97.7 286.5 484.5 257.6 379.2 111.4 304.1 132.5 43.9 24.0 31.1 8.5 56.6 13.0 13.4 15.2 10.1 34.9 12.2 11.5 7.9 3.2 29.3 57.0 13.0 36.8 22.0 11.2 13.0 12.7 14.7 10.0 16.6 16.6 15.8 17.1 14.8 13.1 15.7 19.7 16.0 20.2 0.3 49.7 89.3 58.8 54.1 27.3 0.0 53.2 38.0 11.5 4.3 28.2 1.8 0.0 31.5 48.2 19.9 3.9 55.7 3.9 9.7 104.7 35.1 19.1 104.1 1.0 107.9 56.9 45.6 68.8 21.7 53.3 8.7 19.2 0.8 66.2 0.0 3.7 64.0 38.7 61.6 243.6 3.8 22.7 100.6 71.2 12.2 184.1 0.0 27.8 6.6 1.1 81.2 7.5 21.1 141.2 95.7 3.3 3.3 8.5 0.0 138.1 126.3 239.0 36.5 54.9 42.0 74.6 14.0 71.4 21.6 34.0 64.2 SLC4A5 NBC4 ENSG00000188687 "Solute carrier family 4 member 5" Q9BY07 2 74216242-74343414 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Sodium transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 73.4;retina: 42.0;thyroid gland: 26.7" "Cell type enriched" "Detected in many" 4 "Horizontal cells: 168.2" "Cancer enriched" "Detected in single" 11 "thyroid cancer: 3.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "U-266/70: 8.8" "Group enriched" "Detected in many" 5 "basal ganglia: 1.6;hippocampal formation: 5.2;pons and medulla: 6.5;thalamus: 3.5" "Low region specificity" "Detected in many" HPA036621 Uncertain NA NA "Cluster 11: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036621: AB_10696779" "unprognostic (1.30e-1)" "unprognostic (3.78e-2)" "unprognostic (2.75e-2)" "unprognostic (1.83e-4)" "unprognostic (3.38e-1)" "unprognostic (2.36e-2)" "unprognostic (2.56e-3)" "unprognostic (5.37e-4)" "unprognostic (1.39e-1)" "unprognostic (2.55e-1)" "unprognostic (1.55e-3)" "unprognostic (3.24e-2)" "unprognostic (1.72e-5)" "unprognostic (1.57e-1)" "unprognostic (1.06e-2)" "unprognostic (8.47e-2)" "unprognostic (9.27e-4)" 1.6 0.7 3.3 1.1 5.2 2.3 1.4 12.5 4.6 1.3 73.4 1.2 0.7 1.4 2.3 0.9 2.1 1.0 1.4 6.1 4.1 1.0 1.0 2.6 1.8 5.3 4.8 1.6 1.5 12.4 2.4 0.6 4.8 1.2 0.7 42.0 1.7 1.3 1.8 5.0 1.0 1.5 2.8 1.3 0.9 16.1 5.3 1.0 26.7 1.5 0.8 1.1 1.1 8.5 0.3 0.5 0.9 0.9 0.9 1.6 0.9 0.2 0.9 0.5 0.7 0.3 0.7 1.5 0.2 0.0 0.3 0.1 1.0 0.1 0.2 1.2 0.6 2.2 0.7 0.5 0.1 0.5 1.3 0.4 1.3 0.0 0.2 0.5 0.3 1.0 0.5 1.5 0.2 3.5 0.3 1.5 0.4 0.5 0.3 0.8 0.7 0.0 0.2 0.6 0.6 1.2 0.3 1.1 1.6 0.7 0.8 1.5 0.0 0.9 1.6 0.9 0.3 8.8 1.4 1.0 0.6 0.8 0.2 4.3 0.3 0.3 0.6 0.3 0.4 0.7 1.0 0.9 0.3 0.9 0.8 1.0 1.9 0.7 0.1 2.5 1.2 0.2 3.3 5.2 12.5 4.6 6.1 4.1 5.3 4.8 4.8 2.8 5.3 8.5 1.1 3.2 10.8 16.0 0.5 0.6 0.6 0.3 0.0 13.9 0.6 0.5 0.4 1.5 2.6 0.0 35.5 0.1 3.3 0.3 0.0 0.4 0.6 1.0 0.7 0.9 0.0 0.4 7.3 0.6 0.0 0.8 0.0 0.8 0.0 1.1 0.7 0.0 0.1 168.2 10.6 0.5 0.0 0.0 0.4 0.6 1.2 0.4 1.8 4.7 0.1 3.3 2.1 4.0 31.1 0.5 0.3 0.4 0.1 0.6 0.3 0.1 4.1 40.4 0.0 2.5 1.1 1.7 1.3 0.0 0.4 0.0 0.6 0.3 0.2 0.7 DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009108, HPA034635, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No 250000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB009108: AB_2090601, HPA034635: AB_2674256, HPA071875: " "unprognostic (1.14e-1)" "unprognostic (7.19e-2)" "unprognostic (1.33e-3)" "unprognostic (4.08e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-1)" "unprognostic (4.61e-3)" "unprognostic (2.11e-2)" "unprognostic (2.79e-1)" "unprognostic (3.73e-3)" "unprognostic (1.87e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.34e-7)" "unprognostic (5.41e-2)" "unprognostic (3.11e-1)" "unprognostic (7.86e-3)" "unprognostic (1.12e-3)" 43.3 40.0 90.5 27.0 94.7 23.7 37.4 76.4 113.2 44.3 20.8 51.3 22.2 51.4 17.0 42.6 38.7 28.2 82.6 99.9 80.1 27.6 18.2 36.0 22.8 110.9 85.1 39.2 28.6 118.0 61.2 32.6 112.6 30.0 25.5 43.5 56.3 38.0 87.6 44.2 32.2 49.9 76.0 26.5 39.5 51.3 101.9 34.7 31.3 63.4 24.6 47.6 39.0 116.2 65.0 74.7 68.4 71.9 122.5 90.7 55.2 102.0 105.2 127.0 89.9 99.9 48.6 88.8 40.8 213.0 70.1 63.5 84.3 129.5 96.1 111.2 85.0 92.5 55.6 84.7 94.4 50.7 109.3 109.6 62.0 138.3 82.3 86.9 110.3 79.4 40.3 61.4 97.3 55.6 92.8 52.5 74.0 78.6 78.3 82.3 120.1 63.8 70.2 39.6 83.3 74.1 57.1 67.7 60.6 59.0 43.5 36.5 84.3 115.0 82.7 50.0 77.2 37.8 32.7 78.9 107.6 81.4 82.5 8.3 11.3 12.7 14.4 13.0 11.7 10.1 8.2 10.8 11.2 6.8 5.6 6.3 9.2 9.2 15.6 8.8 7.7 16.5 90.5 94.7 76.4 113.2 99.9 80.1 110.9 85.1 112.6 76.0 101.9 116.2 28.6 32.1 25.4 9.8 23.2 10.1 10.3 19.1 25.6 27.2 19.6 17.8 56.4 18.6 20.0 29.5 25.0 29.8 19.4 41.0 19.6 22.5 7.3 21.5 32.8 26.6 16.7 27.3 28.4 19.9 27.1 25.1 49.5 27.8 29.2 30.8 29.6 19.9 28.8 90.9 26.7 31.8 24.4 21.0 11.3 9.3 44.7 21.2 16.0 8.4 27.3 14.9 23.7 12.1 29.7 26.6 33.6 51.9 24.7 9.6 34.2 19.6 19.4 45.5 19.7 28.3 30.0 40.6 38.5 29.0 11.8 25.2 20.0 33.9 24.9 10.7 C2orf81 "hCG40743, LOC388963" ENSG00000284308 "Chromosome 2 open reading frame 81" A6NN90 2 74414176-74421591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.3" "Cell type enhanced" "Detected in many" "Early spermatids: 45.6;Late spermatids: 31.4;Respiratory ciliated cells: 25.7;Spermatocytes: 20.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 15.1;RPMI-8226: 14.5;SCLC-21H: 17.8;SH-SY5Y: 19.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049564, HPA054835" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli fibrillar center" "HPA049564: , HPA054835: AB_2682620" 2.1 1.5 3.4 1.7 3.9 0.5 2.6 3.7 4.7 5.7 10.0 3.1 1.1 4.9 0.8 1.1 17.7 2.4 2.0 4.4 4.2 5.1 0.7 3.8 2.6 6.1 6.3 4.0 2.2 5.5 17.6 0.6 3.7 5.0 0.4 3.0 2.1 2.5 0.7 1.6 2.5 0.9 4.6 3.7 2.1 27.3 3.6 2.2 3.7 0.5 0.8 3.1 2.5 3.5 4.4 8.0 2.4 8.6 2.6 2.2 0.8 0.6 2.6 0.7 0.8 0.2 4.9 10.5 1.8 1.3 2.1 1.6 0.2 2.1 0.8 5.9 0.4 1.1 0.5 0.0 1.3 2.1 2.1 1.3 5.2 1.0 1.0 3.0 0.1 5.6 0.2 1.6 1.3 15.1 2.7 5.5 4.6 2.4 1.7 1.4 0.8 14.5 3.2 1.9 17.8 19.3 2.4 3.9 1.3 0.3 3.7 1.9 0.0 0.9 3.8 2.7 2.2 3.7 7.4 3.4 5.2 2.0 1.8 0.1 1.9 0.0 0.6 2.0 0.3 6.6 0.7 0.8 6.3 5.8 3.3 1.6 0.1 3.0 1.5 13.3 0.7 1.3 3.4 3.9 3.7 4.7 4.4 4.2 6.1 6.3 3.7 4.6 3.6 3.5 1.7 0.0 2.4 0.0 0.8 0.6 1.0 2.9 1.8 0.9 1.9 4.7 1.4 4.3 3.6 3.7 0.0 0.0 2.9 0.7 5.9 3.2 45.6 11.7 1.9 2.1 7.2 0.0 1.1 2.2 0.0 4.1 0.5 3.1 0.0 1.1 4.2 0.0 0.0 3.3 0.9 1.7 4.1 1.9 3.4 31.4 3.4 1.1 3.6 1.0 6.1 6.1 1.0 1.0 0.2 2.6 0.3 7.5 0.2 0.7 0.4 5.9 25.7 3.9 6.6 2.4 3.9 20.1 1.5 0.1 0.9 0.0 0.6 1.2 1.2 0.3 WDR54 FLJ12953 ENSG00000005448 "WD repeat domain 54" Q9H977 2 74421678-74425755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 70.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 207.0;Late spermatids: 124.6;Respiratory ciliated cells: 395.9;Spermatocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043257, HPA053558" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA043257: AB_10795981, HPA053558: AB_2682189" "unprognostic (1.12e-1)" "unprognostic (3.68e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-2)" "unprognostic (2.62e-1)" "unprognostic (3.06e-3)" "unprognostic (4.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (7.25e-3)" "unprognostic (3.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.85e-2)" 8.2 8.5 11.0 6.5 11.7 6.7 7.7 8.5 11.2 11.8 17.6 6.7 3.2 10.4 5.6 3.4 70.2 8.4 4.3 11.8 14.2 12.1 1.9 10.7 11.6 10.3 12.5 10.8 6.3 30.0 24.4 6.3 11.2 7.4 4.0 28.0 5.2 9.9 1.3 4.9 7.0 7.7 10.8 12.2 7.0 38.0 11.7 18.5 7.8 1.7 11.2 8.6 6.3 9.9 44.9 78.3 37.9 32.5 14.0 25.7 11.8 22.5 45.8 56.8 52.8 6.9 34.4 39.3 22.5 25.1 34.5 37.6 27.8 100.6 49.8 30.3 16.8 19.4 42.4 4.7 14.3 30.6 15.3 11.6 27.6 58.1 30.3 67.5 30.6 61.6 7.7 45.8 32.4 69.8 48.6 32.3 30.3 10.9 29.8 41.2 44.1 84.4 51.3 22.4 66.4 52.1 17.6 15.9 27.0 11.2 25.6 14.7 15.3 29.2 50.9 32.1 50.7 49.2 26.7 10.1 86.5 18.8 21.6 6.6 8.5 0.6 31.1 11.5 31.4 24.2 35.5 33.7 28.6 22.0 25.1 23.8 0.7 29.1 10.1 46.7 36.8 21.6 11.0 11.7 8.5 11.2 11.8 14.2 10.3 12.5 11.2 10.8 11.7 9.9 20.0 3.2 12.8 1.3 23.1 7.0 20.1 64.1 10.2 48.3 9.4 10.9 1.7 20.0 39.4 23.9 83.4 9.8 30.1 1.5 19.6 28.5 77.8 207.0 18.5 25.1 28.9 5.5 5.6 6.0 14.6 14.3 7.1 9.2 12.7 23.8 30.0 1.9 8.6 32.0 4.1 6.0 38.7 6.9 17.4 124.6 17.1 7.4 12.4 0.0 29.8 51.9 26.8 3.0 2.4 13.6 4.4 22.2 17.5 9.4 0.8 28.4 395.9 112.5 0.0 8.4 30.6 147.9 19.3 1.7 4.8 2.9 30.5 37.2 3.8 13.3 RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 149.6;liver: 124.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 4 "dendritic cells: 6.6;NK-cells: 2.3" "Cell line enhanced" "Detected in many" "Hep G2: 96.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria Nucleoplasm "HPA030259: AB_10601484" "unprognostic (4.09e-1)" "unprognostic (1.28e-1)" "unprognostic (1.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-3)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (2.57e-2)" "unprognostic (9.43e-3)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (2.96e-2)" "unprognostic (7.15e-2)" "unprognostic (1.85e-1)" "unprognostic (5.81e-2)" "unprognostic (1.23e-3)" 9.8 8.3 69.5 5.0 104.1 0.6 11.3 85.4 84.6 13.5 51.9 20.3 31.8 8.7 3.5 20.8 12.7 14.2 17.3 72.0 84.3 54.4 124.7 10.3 3.1 100.4 95.5 7.7 30.8 20.7 14.7 11.8 95.7 19.1 12.6 1.9 26.0 9.5 12.8 32.0 25.3 6.3 73.4 5.2 15.3 3.3 93.5 6.3 19.5 7.5 5.3 8.3 16.6 149.6 50.4 15.5 19.5 56.3 11.8 13.7 82.1 7.6 9.9 11.0 8.0 76.3 26.8 0.3 21.2 7.4 13.6 67.2 7.3 48.6 5.3 9.9 31.3 12.0 2.8 96.7 7.2 0.0 0.1 8.4 37.7 9.5 30.0 20.2 5.5 0.7 6.2 0.3 16.5 35.8 1.9 10.1 20.9 70.9 30.3 11.1 60.6 7.6 52.4 0.3 19.0 18.8 20.7 79.3 45.2 17.5 44.6 4.4 0.6 20.5 14.0 9.3 10.6 4.8 3.7 1.8 19.6 0.1 19.5 0.0 0.0 0.0 0.2 0.0 0.2 0.7 0.1 0.2 0.6 1.0 0.0 0.1 0.0 2.3 0.0 6.6 0.0 0.4 69.5 104.1 85.4 84.6 72.0 84.3 100.4 95.5 95.7 73.4 93.5 149.6 4.3 9.6 11.8 4.9 2.0 20.0 22.1 37.2 19.4 0.1 14.4 12.2 3.1 28.6 18.3 11.0 2.1 46.7 4.5 21.7 21.5 43.0 0.7 12.6 6.1 8.8 30.7 1.3 0.5 20.1 8.3 8.9 15.8 26.0 1.3 4.9 5.3 40.1 10.1 0.0 0.9 20.1 18.3 2.2 3.8 1.5 12.8 1.1 28.4 3.7 0.7 6.9 5.2 34.7 48.2 30.5 31.0 8.6 1.4 35.4 44.7 54.7 5.8 0.4 6.6 36.9 3.9 1.1 5.6 12.9 21.6 33.4 2.5 3.1 30.5 15.6 INO80B "hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4" ENSG00000115274 "INO80 complex subunit B" Q9C086 2 74455087-74457944 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 28.0;Suprabasal keratinocytes: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA070644, HPA078274" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Nucleoli, Nuclear bodies" "HPA070644: AB_2732159, HPA078274: " "prognostic favorable (2.89e-4)" "unprognostic (2.24e-2)" "unprognostic (5.62e-2)" "unprognostic (6.59e-3)" "unprognostic (9.45e-2)" "unprognostic (3.82e-2)" "unprognostic (2.20e-3)" "unprognostic (1.21e-2)" "unprognostic (1.16e-1)" "unprognostic (1.54e-2)" "unprognostic (7.52e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.56e-5)" "prognostic favorable (8.44e-4)" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (1.18e-3)" 26.3 30.5 18.9 18.0 20.7 20.6 29.1 17.2 27.6 38.1 15.7 24.1 19.4 30.4 17.1 31.1 31.5 15.1 20.1 19.6 17.5 27.4 32.1 25.9 18.9 18.4 17.1 48.1 41.9 19.6 42.0 11.6 19.2 34.7 12.3 18.7 29.9 17.9 30.1 40.8 23.9 14.8 14.2 24.5 32.7 31.0 16.7 12.8 39.3 9.1 20.1 27.1 32.2 20.9 27.8 29.0 11.0 14.2 21.0 29.6 28.2 25.7 23.0 19.4 16.3 19.9 34.4 46.7 32.2 18.8 18.2 29.1 9.1 20.4 15.8 42.5 28.8 35.9 14.5 20.5 22.4 33.9 17.2 29.5 35.0 27.8 31.2 48.4 26.2 27.4 20.7 18.5 16.5 32.7 44.3 47.7 7.7 20.2 39.7 26.3 34.9 47.4 23.5 18.9 16.7 31.8 13.5 37.3 15.4 12.1 16.1 11.6 22.1 17.7 27.9 29.7 20.0 65.8 48.4 16.9 33.3 21.3 18.9 3.2 2.5 1.0 1.2 1.9 1.6 2.6 1.4 0.7 1.6 2.1 1.2 1.1 3.2 2.1 1.7 3.2 2.2 0.9 18.9 20.7 17.2 27.6 19.6 17.5 18.4 17.1 19.2 14.2 16.7 20.9 4.4 0.0 2.2 0.0 5.4 28.0 2.8 8.5 2.2 14.0 11.3 6.0 0.9 4.3 6.8 3.7 12.5 4.3 7.1 5.8 0.0 15.9 3.0 6.5 5.7 5.4 4.8 9.3 0.0 27.0 4.7 3.4 2.6 3.8 5.7 2.4 6.8 10.8 5.6 13.5 0.0 7.9 12.2 9.7 21.0 6.5 3.1 4.3 5.4 0.0 12.5 4.7 9.2 0.0 0.0 17.4 3.3 3.0 5.1 2.2 11.6 6.5 12.3 15.0 0.0 2.1 4.9 5.6 1.9 3.3 31.7 5.3 7.5 2.2 6.7 2.0 WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Gastric mucus-secreting cells: 33.1;Plasma cells: 57.2;Squamous epithelial cells: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057067 Approved Approved Cytosol No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Cytosol "HPA057067: AB_2683326" "unprognostic (5.94e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (1.04e-4)" "unprognostic (6.05e-2)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (5.80e-2)" "unprognostic (1.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "prognostic favorable (6.83e-4)" "unprognostic (1.17e-2)" "unprognostic (1.87e-2)" "unprognostic (1.78e-1)" "unprognostic (1.57e-1)" "unprognostic (5.09e-2)" "prognostic favorable (6.36e-4)" 36.9 70.7 141.7 19.6 145.8 31.9 37.7 139.4 171.9 48.2 133.1 46.6 29.1 39.1 44.8 35.7 56.1 36.5 49.9 137.7 136.6 71.2 80.3 33.7 32.2 144.2 141.3 55.6 62.3 73.7 60.8 24.9 138.2 69.9 17.7 24.4 56.4 37.3 31.4 34.9 33.2 19.8 138.1 42.5 58.0 31.8 145.0 44.7 66.9 53.9 20.6 45.7 37.5 139.0 20.6 91.3 56.2 66.7 69.9 54.0 45.7 20.6 40.3 22.4 17.5 47.3 41.9 19.4 39.3 48.9 33.2 28.3 24.8 55.8 19.0 74.3 49.1 27.4 41.4 68.9 47.6 10.3 27.4 76.2 58.9 30.4 42.2 93.8 44.7 51.6 11.5 72.0 54.8 133.8 40.1 25.5 43.3 53.6 46.3 36.4 63.5 33.6 55.9 83.1 35.0 81.3 28.2 49.9 62.5 49.4 65.5 26.9 26.5 53.0 41.9 20.0 23.5 106.7 38.8 22.2 56.2 27.0 48.5 24.1 28.5 19.2 26.5 23.5 22.5 28.4 23.0 25.5 30.2 27.8 31.3 28.0 18.6 34.6 20.1 47.0 39.2 27.1 141.7 145.8 139.4 171.9 137.7 136.6 144.2 141.3 138.2 138.1 145.0 139.0 1.5 3.2 4.2 0.0 14.3 0.9 0.6 2.0 29.0 1.6 3.2 2.2 0.5 0.0 4.2 1.8 2.1 1.4 1.7 3.3 1.9 5.5 2.4 3.1 2.4 3.6 1.8 9.7 0.0 3.9 1.4 7.2 33.1 1.8 1.3 1.1 0.4 0.8 1.7 0.0 0.0 4.7 2.0 2.4 1.0 1.8 2.1 7.1 0.0 0.0 6.0 1.7 2.1 0.0 0.0 5.2 3.1 1.2 57.2 1.2 5.6 3.3 13.1 1.7 0.0 0.5 5.8 0.6 0.2 28.1 1.3 1.8 10.4 0.9 3.7 0.3 MOGS "CWH41, DER7, GCS1" ENSG00000115275 "Mannosyl-oligosaccharide glucosidase" Q13724 2 74461057-74465410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011322, HPA011969" Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA011322: AB_2668483, HPA011969: AB_1849579" "unprognostic (5.66e-2)" "unprognostic (1.98e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.91e-2)" "unprognostic (4.67e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (2.34e-6)" "unprognostic (1.48e-2)" "unprognostic (2.66e-2)" "unprognostic (3.32e-2)" "unprognostic (6.21e-2)" "unprognostic (4.36e-1)" "prognostic unfavorable (2.79e-8)" "unprognostic (1.40e-2)" "unprognostic (3.06e-2)" "unprognostic (2.66e-1)" "unprognostic (7.59e-3)" 18.4 18.3 8.1 20.2 9.1 8.5 18.6 9.0 13.3 19.2 9.2 22.8 41.7 18.3 5.5 22.5 20.0 14.4 16.9 8.3 9.0 20.9 34.3 24.9 21.6 9.4 8.7 18.6 42.3 21.5 21.7 34.5 9.9 23.3 13.4 9.6 31.1 14.6 21.3 24.9 29.7 11.4 9.3 31.7 35.5 19.0 8.9 19.8 21.9 16.2 18.1 20.1 19.1 9.8 53.1 46.2 23.5 29.6 55.3 38.9 90.1 38.7 58.3 59.8 58.2 81.9 58.7 45.2 34.9 36.3 46.7 50.6 40.2 43.3 32.5 46.7 39.9 20.3 14.4 68.6 54.9 49.8 46.6 25.6 77.1 41.9 39.0 62.2 68.4 27.8 39.6 51.6 28.5 58.8 32.3 62.0 42.6 64.1 22.5 35.5 57.4 74.1 38.0 19.5 19.7 29.2 15.5 84.8 62.7 21.8 38.7 34.3 40.1 26.5 49.7 36.3 56.5 66.5 36.5 22.7 46.9 49.3 39.0 6.7 2.4 1.9 2.6 1.5 3.3 1.2 2.3 2.5 2.1 1.9 1.4 1.6 0.4 8.4 3.3 2.1 3.3 1.7 8.1 9.1 9.0 13.3 8.3 9.0 9.4 8.7 9.9 9.3 8.9 9.8 13.9 6.4 15.9 16.3 22.0 15.8 21.8 20.8 18.2 14.9 18.9 12.8 8.6 24.3 21.3 23.9 18.8 39.5 34.6 18.7 5.9 21.9 65.6 12.4 12.2 13.3 13.9 16.4 13.9 26.1 50.5 12.3 40.8 17.4 4.5 20.9 17.9 25.6 19.9 6.7 12.1 25.7 20.3 12.9 14.8 222.0 15.2 17.9 10.6 12.2 25.5 7.0 30.9 11.1 10.7 22.3 19.7 7.2 43.6 22.7 37.7 7.4 17.7 14.1 13.1 9.4 12.7 13.0 5.1 15.2 17.3 52.0 21.2 16.5 23.3 19.6 MRPL53 ENSG00000204822 "Mitochondrial ribosomal protein L53" Q96EL3 2 74471982-74472687 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034612, HPA056185" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA034612: , HPA056185: AB_2683060" "unprognostic (2.22e-2)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (7.36e-5)" "unprognostic (3.60e-2)" "unprognostic (1.24e-1)" "unprognostic (4.06e-2)" "prognostic favorable (1.37e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.16e-8)" "unprognostic (8.76e-2)" "unprognostic (2.79e-1)" "unprognostic (4.13e-1)" "unprognostic (2.45e-2)" 60.9 82.9 68.8 46.8 72.2 61.8 38.9 77.0 98.9 31.3 79.2 41.5 48.0 28.7 39.1 41.0 50.2 34.0 114.4 67.1 72.3 54.5 65.1 34.2 78.4 72.3 69.3 61.5 118.0 72.1 35.1 34.8 72.7 46.0 20.3 27.1 107.1 36.2 169.7 27.3 45.9 24.4 74.2 54.7 55.0 23.1 70.2 50.3 47.1 89.0 42.3 44.7 27.0 76.5 101.5 271.0 60.0 58.5 77.9 69.7 103.4 79.8 73.7 70.5 60.9 224.7 130.1 87.6 78.8 61.4 97.3 76.3 32.5 105.7 24.5 174.6 188.3 77.7 115.6 133.7 70.7 88.4 85.6 96.7 75.1 90.4 59.0 82.3 75.3 109.0 93.0 156.6 63.8 316.5 118.6 163.3 57.5 166.0 204.5 89.1 196.0 212.9 88.9 115.6 103.5 128.0 74.1 195.6 137.3 40.8 102.3 111.1 83.6 115.9 119.6 101.7 135.2 292.3 260.6 141.1 116.4 94.8 125.8 244.9 293.8 133.8 168.2 277.6 188.5 350.0 215.9 173.1 250.3 367.5 282.0 211.4 185.5 167.6 271.8 360.3 275.3 345.5 68.8 72.2 77.0 98.9 67.1 72.3 72.3 69.3 72.7 74.2 70.2 76.5 5.2 9.6 23.2 4.6 18.0 17.2 6.0 9.7 12.0 2.0 24.0 16.4 1.6 4.3 12.1 11.0 0.0 14.7 10.5 29.5 21.5 32.8 8.9 7.2 4.3 11.2 39.7 18.9 3.4 56.9 17.5 10.9 15.3 4.7 33.6 3.0 16.1 23.8 18.0 1.7 3.5 27.2 6.1 25.9 23.9 2.3 8.7 15.6 26.6 2.8 35.8 4.6 15.5 2.0 7.1 35.8 43.5 4.5 34.8 4.9 41.8 45.3 46.1 4.0 6.6 7.7 11.2 11.2 6.8 16.6 25.1 15.7 14.6 3.3 21.7 6.9 CCDC142 FLJ14397 ENSG00000135637 "Coiled-coil domain containing 142" Q17RM4 2 74471986-74483408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.3;Respiratory ciliated cells: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056946 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA056946: AB_2683282" "unprognostic (2.00e-1)" "unprognostic (3.25e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.73e-1)" "unprognostic (1.69e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (9.05e-2)" "unprognostic (5.15e-2)" "unprognostic (2.44e-2)" "unprognostic (5.65e-3)" "unprognostic (8.94e-3)" "prognostic unfavorable (3.71e-7)" "unprognostic (1.31e-1)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "unprognostic (5.31e-3)" 1.9 2.6 3.0 2.4 2.9 1.5 1.9 5.6 3.5 2.7 3.6 2.8 4.4 2.6 1.3 2.4 2.4 1.2 1.8 2.8 2.6 2.2 4.6 1.8 2.6 3.5 2.7 2.6 2.2 2.7 2.9 1.2 3.1 2.8 1.9 1.3 2.4 2.0 1.5 2.6 3.3 1.5 2.3 3.3 2.4 3.2 3.1 2.5 2.4 1.2 2.2 2.3 2.0 4.1 2.7 2.1 4.3 3.4 2.8 2.7 7.5 4.0 2.4 3.2 2.4 6.3 3.8 3.2 2.6 2.5 3.9 4.8 2.8 3.1 2.1 4.5 8.9 5.6 7.7 4.6 1.2 3.6 4.2 1.9 2.1 5.0 2.1 4.1 2.5 3.8 2.6 2.2 3.0 2.3 4.8 3.6 4.1 4.7 5.3 5.7 7.8 2.9 1.9 3.9 5.5 3.4 3.1 6.4 3.5 3.1 4.3 2.5 2.1 6.3 4.0 4.4 4.9 6.6 3.1 3.2 2.9 1.9 3.7 6.3 3.0 5.9 5.1 1.8 4.1 3.3 2.9 3.6 1.6 5.3 4.6 3.8 2.4 4.7 3.8 2.9 1.4 1.1 3.0 2.9 5.6 3.5 2.8 2.6 3.5 2.7 3.1 2.3 3.1 4.1 2.5 9.6 28.3 3.3 6.1 3.2 2.4 1.4 1.8 16.4 2.8 2.0 4.1 2.8 16.2 0.0 18.8 3.1 6.1 6.2 1.9 2.7 1.1 1.3 4.2 5.6 6.0 4.8 3.3 2.0 2.2 6.7 4.1 1.8 18.3 8.6 6.8 2.1 2.0 5.0 3.6 5.3 0.0 3.3 3.0 0.4 7.5 5.8 0.0 5.6 4.2 11.5 16.5 2.5 2.4 1.5 5.7 6.0 4.6 1.7 14.0 1.3 31.2 22.9 0.0 6.1 4.0 8.1 5.0 1.2 3.0 1.9 7.7 5.9 6.3 2.0 TTC31 FLJ12788 ENSG00000115282 "Tetratricopeptide repeat domain 31" Q49AM3 2 74483073-74494559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041783 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA041783: AB_10794306" "unprognostic (2.38e-2)" "unprognostic (7.44e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.70e-4)" "unprognostic (2.64e-1)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (6.56e-2)" "unprognostic (7.22e-2)" "unprognostic (7.61e-2)" "unprognostic (1.13e-2)" "unprognostic (1.46e-3)" "unprognostic (9.61e-2)" "unprognostic (3.24e-1)" "unprognostic (4.83e-2)" "prognostic favorable (2.49e-4)" 6.4 4.8 3.5 8.4 3.9 9.0 4.8 3.4 4.3 5.4 3.8 7.9 11.1 5.9 4.5 6.1 5.9 5.9 5.7 3.3 3.6 6.0 18.7 6.8 9.8 4.3 3.8 6.3 7.9 9.2 3.2 9.2 3.9 5.2 8.2 4.8 4.7 4.5 3.7 8.8 9.9 7.4 3.8 8.2 7.5 3.2 3.8 9.7 4.8 3.9 10.6 5.7 4.6 4.5 16.0 13.1 11.7 6.3 7.3 17.0 12.9 11.2 11.4 16.2 11.9 11.3 13.0 20.6 6.4 9.5 14.2 11.8 9.5 10.5 11.0 23.0 8.3 22.4 12.9 24.9 11.0 10.1 21.5 11.5 13.7 14.0 9.8 14.3 11.0 12.0 15.0 11.5 12.0 13.7 17.4 9.2 7.6 12.2 7.9 13.7 24.0 11.5 11.5 11.8 5.6 16.5 7.9 12.4 10.2 7.4 9.7 6.2 17.6 12.5 18.7 9.5 12.6 13.6 10.8 14.1 13.5 12.5 11.4 4.9 8.3 6.1 6.5 8.1 7.2 7.0 4.9 6.2 8.1 4.7 4.6 5.4 0.8 6.6 8.7 4.4 7.3 7.4 3.5 3.9 3.4 4.3 3.3 3.6 4.3 3.8 3.9 3.8 3.8 4.5 5.4 16.0 9.2 7.2 10.8 2.8 4.1 5.2 4.6 11.1 5.2 5.0 3.5 14.3 7.8 9.2 39.6 8.3 9.8 7.8 1.9 5.8 4.6 3.8 8.0 6.7 6.1 13.3 3.0 5.5 5.3 6.0 7.1 5.9 19.0 8.8 4.6 20.8 8.3 5.0 3.4 5.9 6.1 7.9 3.5 5.0 6.2 7.5 3.6 10.3 13.2 9.2 19.6 2.5 4.4 5.9 9.4 5.7 9.6 3.1 13.9 6.0 4.3 23.6 6.6 7.3 5.3 8.3 10.0 4.2 3.3 8.1 9.8 8.2 6.5 3.8 LBX2 ENSG00000179528 "Ladybird homeobox 2" Q6XYB7 2 74497517-74503316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.3;liver: 8.7;stomach 1: 3.2" "Cell type enhanced" "Detected in some" "Hepatocytes: 3.7;Proximal tubular cells: 7.5;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 10.5;Hep G2: 22.1;SK-MEL-30: 10.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 1.9;olfactory bulb: 1.0" HPA044257 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Midbody "HPA044257: AB_2678880" "unprognostic (5.24e-2)" "unprognostic (7.97e-2)" "unprognostic (2.35e-5)" "unprognostic (8.22e-4)" "unprognostic (2.95e-1)" "unprognostic (2.94e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-1)" "unprognostic (2.76e-2)" "unprognostic (1.85e-1)" "unprognostic (3.25e-2)" "unprognostic (1.43e-5)" "unprognostic (5.77e-2)" "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" 1.3 0.3 0.3 0.4 0.3 0.4 0.6 0.9 0.4 0.4 0.0 1.1 5.3 0.3 0.2 0.2 0.2 0.4 0.3 0.1 0.2 1.3 8.7 0.5 0.4 0.5 0.2 0.1 0.7 0.1 0.0 0.5 0.5 0.3 0.1 0.1 0.5 0.3 0.4 0.9 4.8 0.2 0.1 1.1 3.2 0.1 0.4 0.0 0.3 0.0 0.1 0.3 0.2 1.3 4.4 1.6 0.0 0.1 2.0 1.5 7.1 0.3 0.2 0.4 0.4 10.5 6.2 0.2 1.7 0.8 0.6 1.7 0.0 0.3 0.0 9.0 1.8 4.7 0.7 22.1 1.4 0.3 3.0 1.9 1.6 1.6 0.3 0.2 1.8 0.1 3.1 2.2 0.3 2.3 0.1 0.7 0.4 1.7 0.2 0.4 0.4 0.2 0.2 1.4 0.2 1.1 2.6 0.4 10.1 0.1 0.2 0.3 4.1 1.5 6.6 8.1 0.2 2.9 2.3 0.2 1.5 0.8 4.8 0.5 1.5 0.1 0.3 0.8 0.2 0.0 0.1 0.4 0.8 0.0 0.1 0.2 0.6 1.1 2.2 0.2 0.0 0.7 0.3 0.3 0.9 0.4 0.1 0.2 0.5 0.2 0.5 0.1 0.4 1.3 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.7 0.5 0.7 1.5 0.5 1.8 0.0 0.3 0.5 0.9 0.0 0.6 0.0 0.4 0.5 1.0 2.4 0.4 0.0 0.6 0.5 1.3 1.1 0.2 0.0 0.0 1.4 3.7 1.1 0.0 0.0 0.2 0.0 0.6 0.3 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 0.0 2.4 7.5 0.7 0.0 6.6 0.0 0.9 0.4 0.1 0.3 0.1 0.5 0.5 0.2 1.0 0.1 PCGF1 "MGC10882, NSPC1, RNF68" ENSG00000115289 "Polycomb group ring finger 1" Q9BSM1 2 74505043-74507695 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011356, HPA069156" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA011356: AB_1855063, HPA069156: AB_2686095" "unprognostic (2.41e-1)" "unprognostic (5.97e-2)" "unprognostic (1.11e-3)" "unprognostic (2.71e-2)" "unprognostic (4.25e-2)" "unprognostic (2.73e-2)" "unprognostic (2.32e-2)" "unprognostic (4.18e-3)" "unprognostic (2.26e-1)" "unprognostic (2.14e-1)" "unprognostic (1.57e-1)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.00e-1)" "unprognostic (5.09e-2)" "unprognostic (1.21e-1)" "unprognostic (2.13e-1)" 9.9 10.4 13.7 8.6 14.5 17.8 15.2 14.6 17.3 12.8 13.0 11.5 11.2 12.5 14.4 9.7 14.4 10.0 12.3 14.1 13.9 10.9 13.0 12.3 14.1 13.9 13.8 14.8 11.0 17.6 2.3 11.4 14.7 9.3 12.3 18.1 11.0 8.8 12.1 14.8 10.8 11.2 13.7 8.5 11.7 11.0 14.5 14.4 14.2 17.6 14.7 10.7 2.1 15.1 18.9 11.6 12.3 19.0 15.4 19.0 19.0 17.8 23.8 16.2 10.9 25.5 12.8 16.9 7.6 16.5 38.0 11.4 20.7 23.5 14.6 16.3 24.7 12.0 15.7 25.6 24.9 31.7 16.5 25.5 33.3 10.5 57.4 26.0 12.8 21.8 25.0 23.0 17.8 27.8 22.6 42.0 16.3 23.5 12.3 18.0 27.3 14.1 24.8 21.0 14.0 27.8 13.8 27.1 30.1 12.1 10.1 21.4 11.7 26.2 17.5 14.5 24.1 12.5 9.7 18.3 22.1 22.6 16.3 11.1 24.2 10.4 15.5 20.1 18.3 18.1 20.7 19.8 26.9 17.9 16.3 16.8 8.7 14.4 23.3 13.1 24.2 14.2 13.7 14.5 14.6 17.3 14.1 13.9 13.9 13.8 14.7 13.7 14.5 15.1 7.0 3.2 1.8 2.3 8.7 12.5 9.0 23.8 31.3 5.0 10.5 10.9 3.5 12.8 10.6 3.7 4.2 12.2 6.5 9.5 31.3 11.0 19.0 11.3 11.5 8.5 1.2 10.3 1.7 10.4 19.5 13.1 6.1 10.4 10.2 2.9 7.1 6.2 13.6 5.0 1.6 12.8 18.3 9.9 14.0 4.9 7.8 10.8 7.2 0.0 15.0 6.7 19.6 0.5 2.3 11.3 15.9 4.9 11.4 9.4 14.2 17.5 9.5 9.5 6.6 10.4 14.0 19.3 8.0 24.3 18.9 18.3 9.6 5.0 9.4 8.5 TLX2 "Enx, HOX11L1, NCX" ENSG00000115297 "T cell leukemia homeobox 2" O43763 2 74513463-74517148 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 2.0;retina: 3.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 20.9;Rod photoreceptor cells: 18.0;Spermatocytes: 4.3;Spermatogonia: 7.4" "Cancer enhanced" "Detected in single" "cervical cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "SH-SY5Y: 64.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA062254 Approved Nucleoplasm NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA062254: AB_2684727" "unprognostic (7.30e-2)" "unprognostic (3.03e-4)" "unprognostic (9.54e-4)" "unprognostic (2.86e-2)" "unprognostic (2.33e-1)" "unprognostic (1.69e-2)" "unprognostic (6.77e-2)" "unprognostic (1.36e-1)" "unprognostic (9.00e-2)" "unprognostic (3.91e-2)" "unprognostic (1.39e-1)" "unprognostic (5.40e-1)" "unprognostic (3.92e-7)" "unprognostic (2.51e-1)" "unprognostic (6.86e-2)" "unprognostic (5.04e-2)" "unprognostic (1.18e-1)" 0.0 2.0 1.0 0.2 0.3 0.0 0.0 0.4 0.8 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.2 1.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.9 0.0 3.4 0.0 0.0 0.0 0.0 4.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.0 3.2 0.0 0.1 0.1 0.0 0.0 0.0 1.4 3.8 0.2 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.4 0.8 0.1 0.1 0.5 0.4 0.4 0.2 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 20.9 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 4.3 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DQX1 FLJ23757 ENSG00000144045 "DEAQ-box RNA dependent ATPase 1" Q8TE96 2 74518131-74526281 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 16.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 17.3;Gastric mucus-secreting cells: 13.7;Intestinal goblet cells: 17.3;Paneth cells: 13.9;Proximal enterocytes: 44.2;Undifferentiated cells: 12.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 5.8;Hep G2: 18.4;hTCEpi: 6.1;OE19: 15.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039158, HPA046763" Enhanced Approved "Nucleoli fibrillar center" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "HPA039158: AB_10960125, HPA046763: " "unprognostic (2.17e-1)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (9.95e-2)" "unprognostic (2.20e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-1)" "unprognostic (4.54e-2)" "unprognostic (1.68e-1)" "unprognostic (7.67e-2)" "unprognostic (2.21e-2)" "unprognostic (0.00e+0)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-3)" 0.0 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.2 0.4 0.0 6.3 16.4 0.0 0.0 1.6 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 5.6 0.0 0.4 0.0 0.0 1.1 13.9 0.5 0.0 0.1 3.2 0.0 0.1 0.0 0.0 0.0 1.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.1 5.8 0.1 0.0 0.0 0.5 0.2 18.4 0.0 0.2 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 15.5 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 0.0 2.4 0.0 0.9 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.5 0.5 0.1 4.5 4.6 0.4 0.1 0.0 0.3 1.5 3.5 0.0 2.1 1.6 0.0 17.3 0.0 0.0 0.0 0.2 0.1 0.0 2.4 0.0 0.6 0.0 0.8 0.6 13.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 17.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 13.9 0.0 0.4 0.0 44.2 0.0 5.0 0.9 0.0 0.1 0.1 0.6 0.3 3.1 0.0 1.1 0.1 0.0 12.5 0.2 AUP1 ENSG00000115307 "AUP1 lipid droplet regulating VLDL assembly factor" Q9Y679 2 74526645-74529760 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007674 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA007674: AB_1078251" "unprognostic (1.09e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-2)" "unprognostic (2.11e-2)" "unprognostic (5.97e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.00e-1)" "unprognostic (2.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (2.97e-9)" "unprognostic (9.68e-2)" "unprognostic (1.59e-1)" "unprognostic (3.35e-1)" "unprognostic (3.96e-2)" 48.0 42.2 68.0 44.4 69.0 78.8 52.6 71.0 85.8 56.0 72.1 76.9 70.6 38.7 78.6 49.9 45.3 46.0 38.4 67.6 71.0 48.8 106.9 48.7 41.3 73.0 69.6 38.1 127.3 77.6 2.1 60.6 69.7 38.9 81.0 32.4 89.1 46.3 57.7 42.3 68.5 55.8 70.5 39.5 56.7 24.5 70.1 42.5 50.9 66.6 51.5 69.6 20.7 72.1 114.2 133.4 55.3 87.5 183.1 107.7 124.9 89.1 152.6 122.3 77.3 196.9 130.6 126.4 61.9 126.5 210.3 143.4 140.4 115.1 98.5 100.1 128.7 153.6 71.2 180.7 181.5 97.8 127.9 128.5 256.7 174.4 198.6 101.1 117.3 105.1 202.2 164.5 134.0 124.6 79.0 200.6 111.4 298.3 111.9 95.3 150.0 270.3 139.3 90.9 80.7 79.6 65.2 200.4 162.2 70.8 90.2 156.7 59.3 162.9 97.2 50.6 146.8 87.9 88.1 120.4 129.6 155.9 184.9 113.8 132.9 108.9 81.9 169.3 89.6 90.6 81.0 82.0 124.6 113.9 72.9 75.8 68.8 85.3 144.7 118.3 107.9 132.2 68.0 69.0 71.0 85.8 67.6 71.0 73.0 69.6 69.7 70.5 70.1 72.1 64.8 67.3 44.6 22.5 97.3 73.2 120.7 161.1 80.8 31.7 71.4 59.6 34.9 74.4 108.1 68.0 14.6 140.0 86.6 150.4 23.5 125.2 24.3 36.2 50.1 74.9 73.8 72.4 17.7 208.7 217.3 73.0 121.8 58.7 89.9 57.3 50.0 114.3 161.8 37.0 16.1 127.7 136.3 83.5 95.5 29.7 44.4 95.2 97.8 17.8 67.2 74.5 72.1 14.6 23.4 153.1 141.3 38.0 229.9 141.1 196.0 59.6 46.6 43.2 59.2 60.0 104.2 85.9 64.6 95.7 78.7 223.8 77.6 68.4 134.2 143.9 HTRA2 "OMI, PARK13, PRSS25" ENSG00000115317 "HtrA serine peptidase 2" O43464 2 74529725-74533332 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" Apoptosis "Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004004, HPA006602, HPA027366" Uncertain Supported Mitochondria NA NA 260000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "CAB004004: AB_326421, HPA006602: AB_2667622, HPA027366: AB_1851301" "unprognostic (3.09e-1)" "unprognostic (4.06e-2)" "unprognostic (2.82e-1)" "unprognostic (2.58e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (7.77e-8)" "unprognostic (2.12e-3)" "unprognostic (4.18e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-2)" "unprognostic (8.15e-2)" "unprognostic (7.23e-3)" "unprognostic (4.03e-1)" "unprognostic (1.73e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-2)" 11.4 8.6 8.1 8.1 8.7 11.1 6.8 9.1 9.7 7.1 7.7 6.4 6.9 6.9 1.0 6.0 7.1 4.7 9.4 8.1 8.3 8.1 6.5 6.6 7.8 8.6 8.5 10.9 7.4 9.4 4.7 6.3 8.3 4.8 3.3 2.5 8.5 5.3 14.5 5.4 7.9 5.3 8.2 9.9 6.4 6.2 9.6 9.1 6.8 9.0 4.8 6.5 5.8 9.2 19.1 14.7 14.7 12.6 21.3 9.0 30.1 17.0 10.3 10.3 7.0 21.1 8.5 16.6 12.9 10.7 26.0 19.7 12.0 19.6 2.4 34.0 31.4 33.3 10.8 19.0 19.8 15.3 22.4 9.9 13.7 18.4 19.5 18.4 14.2 23.5 43.9 24.9 9.7 14.1 22.0 31.1 10.0 22.8 37.7 15.8 37.0 17.1 9.6 8.2 15.1 17.7 8.9 18.6 32.5 7.3 9.3 13.2 10.6 19.2 19.7 33.4 35.3 29.5 10.2 9.8 13.6 23.4 13.0 5.8 7.0 4.0 4.8 5.7 5.8 11.0 4.8 4.1 8.6 9.9 4.3 4.1 2.6 5.0 4.5 4.5 5.7 5.5 8.1 8.7 9.1 9.7 8.1 8.3 8.6 8.5 8.3 8.2 9.6 9.2 30.7 0.0 4.8 6.2 27.3 20.6 19.7 33.8 13.6 12.0 17.4 21.7 0.9 21.5 15.7 11.0 0.0 24.7 25.8 12.5 35.2 32.4 30.8 11.9 18.1 29.6 9.0 118.5 6.3 17.7 37.8 23.3 11.2 12.9 27.3 20.9 22.9 12.7 31.5 10.1 6.3 12.3 20.3 10.7 19.4 48.9 24.8 14.6 30.2 2.8 26.3 20.2 30.9 5.5 7.5 26.1 16.8 20.7 36.0 21.3 24.8 36.8 13.5 16.3 26.3 18.7 56.5 64.3 43.3 16.7 22.0 20.2 20.6 27.1 20.0 15.7 LOXL3 ENSG00000115318 "Lysyl oxidase like 3" P58215 2 74532258-74555690 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Inflammatory response" Oxidoreductase "Deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Hofbauer cells: 17.9;Kupffer cells: 12.5;Macrophages: 12.3;Microglial cells: 30.0;Muller glia cells: 10.6;Oligodendrocyte precursor cells: 11.6;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "melanoma: 15.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 11.7;non-classical monocyte: 9.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 143.4;HDLM-2: 110.7;U-138 MG: 245.9;WM-115: 549.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035281 Approved "Secreted to extracellular matrix" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "HPA035281: AB_10601766" "unprognostic (7.54e-2)" "unprognostic (2.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.55e-3)" "unprognostic (6.85e-2)" "unprognostic (1.96e-1)" "unprognostic (1.68e-3)" "unprognostic (6.84e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.22e-2)" "unprognostic (7.33e-3)" "unprognostic (7.09e-2)" "unprognostic (3.38e-2)" 6.8 5.3 4.5 7.8 4.7 14.3 3.0 4.5 5.3 5.1 3.8 7.3 4.0 7.4 1.7 3.2 4.9 6.5 8.2 4.5 5.6 2.0 1.5 4.6 4.1 7.0 5.0 2.9 1.1 1.7 2.7 15.9 6.3 3.3 3.7 4.9 1.6 4.0 1.3 2.0 3.9 8.1 5.6 8.9 2.7 2.6 7.0 1.4 2.2 1.5 2.3 5.2 4.0 7.3 1.6 0.3 21.8 3.7 17.1 20.6 4.5 71.0 143.4 33.8 31.8 25.6 1.3 0.1 0.9 73.1 1.6 1.1 2.8 1.8 19.8 110.7 1.0 17.6 1.8 0.2 5.7 0.6 16.7 22.6 0.2 90.6 3.8 12.0 0.7 0.8 0.8 2.8 6.4 4.1 0.2 6.5 12.0 0.8 0.7 2.0 3.1 0.3 0.3 1.2 11.2 12.8 0.6 1.1 14.7 3.2 2.3 1.3 0.3 245.9 8.2 1.4 0.9 1.4 0.5 0.1 92.5 6.8 549.6 0.1 6.0 0.3 0.0 11.7 0.0 0.1 0.1 0.0 3.5 0.1 0.0 0.0 2.5 0.0 9.3 0.4 0.0 2.6 4.5 4.7 4.5 5.3 4.5 5.6 7.0 5.0 6.3 5.6 7.0 7.3 0.9 0.0 0.5 14.0 0.3 0.9 0.2 0.6 0.6 0.9 0.4 0.8 0.3 1.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.8 0.0 0.2 4.8 1.2 0.0 0.4 0.4 0.0 1.5 7.1 0.0 0.5 1.3 0.7 0.4 0.1 17.9 1.7 4.2 0.1 0.0 12.5 2.5 0.7 5.0 12.3 0.0 30.0 4.8 10.6 1.0 11.6 0.6 0.3 0.0 4.5 0.1 0.3 0.0 0.1 0.0 0.9 19.7 1.6 5.3 0.6 0.8 0.1 0.1 0.8 0.4 0.2 0.0 0.2 DOK1 p62dok ENSG00000115325 "Docking protein 1" Q99704 2 74549026-74557551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "granulocytes: 36.8;Hofbauer cells: 48.6;Macrophages: 31.2;monocytes: 41.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004224, HPA048561" Approved Supported Cytosol NA NA 80000 "Cluster 14: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "CAB004224: AB_627447, HPA048561: AB_2680443" "unprognostic (2.40e-2)" "unprognostic (2.07e-2)" "unprognostic (2.60e-1)" "prognostic favorable (8.42e-4)" "unprognostic (9.86e-3)" "unprognostic (1.28e-1)" "unprognostic (7.10e-2)" "prognostic favorable (4.64e-4)" "unprognostic (7.57e-2)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.16e-6)" "unprognostic (8.65e-2)" "unprognostic (2.40e-2)" "unprognostic (1.37e-1)" "unprognostic (1.20e-2)" 10.8 3.7 8.8 10.2 8.3 13.7 4.7 8.2 9.0 6.6 7.6 5.2 4.4 4.9 0.7 1.4 6.3 3.2 2.8 7.8 8.7 2.7 1.5 6.6 12.3 10.7 8.7 4.2 3.7 6.3 2.2 4.0 9.2 3.1 3.8 0.9 3.0 4.0 1.1 1.6 5.8 4.8 9.2 11.6 6.7 1.7 9.4 7.6 3.9 1.7 10.1 4.7 2.7 9.0 5.3 2.0 6.0 3.0 13.9 16.8 4.2 12.8 10.0 5.2 8.5 1.6 6.1 3.3 18.0 12.3 11.3 0.7 6.1 2.8 1.9 76.3 5.7 43.1 4.4 0.3 10.0 22.0 41.0 12.5 0.0 28.5 14.7 21.7 6.2 13.8 12.7 9.5 10.5 5.6 15.8 45.7 11.1 10.8 1.6 13.0 12.9 3.5 2.7 4.5 2.0 10.0 2.5 0.7 6.7 1.7 3.3 24.1 11.7 32.7 15.1 15.3 2.9 12.6 9.6 0.1 32.9 35.3 5.5 39.0 52.3 38.9 17.3 51.4 13.9 22.9 14.1 15.4 51.3 26.3 10.3 10.3 52.9 27.4 59.3 10.8 24.3 39.8 8.8 8.3 8.2 9.0 7.8 8.7 10.7 8.7 9.2 9.2 9.4 9.0 6.7 9.6 8.8 2.9 15.0 2.0 1.1 3.7 1.2 0.5 2.2 2.8 1.8 4.3 2.0 5.5 0.0 1.9 13.6 8.7 0.0 11.9 0.3 7.4 5.8 7.2 3.0 12.4 0.1 9.1 4.2 6.5 6.1 5.6 36.8 5.8 9.7 0.6 48.6 1.7 0.5 5.9 2.0 26.3 24.2 1.0 5.0 31.2 3.6 4.7 41.1 9.8 16.5 0.5 0.6 10.2 10.0 6.0 6.3 2.4 8.1 3.9 1.7 0.5 6.6 4.1 8.3 0.5 2.1 0.3 1.6 2.3 13.5 7.0 6.8 1.6 M1AP "C2orf65, D6Mm5e, SPATA37" ENSG00000159374 "Meiosis 1 associated protein" Q8TC57 2 74557883-74648338 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.0" "Group enriched" "Detected in some" 4 "Spermatocytes: 16.2;Spermatogonia: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 2.1;RT4: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045420, HPA059302" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA045420: AB_10961177, HPA059302: AB_2683972" "unprognostic (1.76e-1)" "unprognostic (6.58e-3)" "unprognostic (1.26e-2)" "unprognostic (2.87e-1)" "unprognostic (9.15e-2)" "unprognostic (1.35e-3)" "unprognostic (1.86e-1)" "unprognostic (2.17e-3)" "unprognostic (3.42e-1)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (6.11e-2)" "unprognostic (7.74e-2)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.46e-1)" 0.3 0.2 1.1 0.1 0.7 2.5 0.5 0.0 1.2 2.5 0.8 0.1 0.1 1.1 0.3 0.1 2.6 0.1 0.0 1.1 0.6 1.0 0.0 0.4 0.1 0.0 0.2 0.0 0.3 1.3 1.8 0.1 0.0 0.1 0.0 0.5 0.9 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.4 8.0 1.7 0.6 2.0 0.0 0.3 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 1.2 1.1 0.6 0.0 0.2 0.0 0.2 1.7 0.3 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.4 0.4 0.0 0.1 3.7 0.0 0.5 0.1 0.2 0.0 0.3 3.1 2.2 0.1 0.0 0.0 0.4 3.1 0.0 1.6 0.0 0.0 0.9 0.0 0.0 0.0 0.1 3.8 0.0 1.0 0.8 0.0 1.6 0.8 3.9 0.0 2.0 0.0 2.8 0.4 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.5 0.2 0.0 0.1 1.8 1.4 0.0 0.1 0.0 16.2 22.5 0.0 0.0 0.3 0.1 0.0 0.1 0.1 SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.5;Inhibitory neurons: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064095, HPA065969" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA064095: AB_2732710, HPA065969: AB_2685590" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" 3.2 2.3 5.4 0.9 7.0 0.4 3.2 3.2 8.2 4.1 0.1 2.5 0.5 3.6 1.7 1.3 3.3 0.8 2.7 8.0 6.3 3.5 1.0 2.5 1.5 4.2 2.1 5.3 2.6 3.0 7.2 0.9 3.9 3.1 1.0 4.7 2.7 1.4 1.4 1.9 2.1 1.6 1.5 2.6 2.2 4.1 8.1 1.2 3.1 1.3 1.4 2.6 3.2 3.8 6.1 3.4 3.7 5.5 5.8 3.3 2.6 3.9 8.9 7.4 6.5 1.4 3.3 2.3 5.0 6.2 14.4 1.9 6.7 5.7 7.5 5.3 7.0 4.4 1.4 3.8 2.3 1.0 5.4 2.6 6.0 4.9 2.4 14.1 2.9 4.4 0.2 0.2 4.8 2.1 3.3 0.8 2.6 2.7 4.0 0.0 5.4 0.0 6.0 2.6 2.9 5.8 7.0 1.8 6.5 5.0 2.6 0.7 4.9 11.5 5.8 2.9 7.1 5.2 5.6 0.3 13.4 0.3 5.6 0.3 0.1 0.7 1.9 0.0 1.2 1.1 1.1 1.7 0.0 0.8 1.1 1.3 0.3 1.0 0.2 0.0 0.9 0.8 5.4 7.0 3.2 8.2 8.0 6.3 4.2 2.1 3.9 1.5 8.1 3.8 2.2 0.0 6.5 4.9 2.7 0.4 1.8 1.8 2.2 8.8 1.8 2.5 2.4 5.7 4.8 5.5 12.5 0.8 1.4 0.7 1.9 2.1 3.2 0.6 0.6 2.2 7.2 0.8 44.5 1.6 2.4 3.3 1.5 1.0 2.5 3.0 3.3 0.6 0.8 11.8 22.7 0.6 2.0 0.0 0.7 3.7 0.9 0.7 0.0 4.7 1.5 3.3 4.1 4.5 5.8 2.7 1.4 1.5 0.7 1.3 0.4 0.3 1.3 6.7 6.6 3.1 1.4 5.6 11.2 0.5 0.4 0.4 3.5 0.5 1.0 1.6 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958643-74970128 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 110.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054979, HPA071815" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 47: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Cytosol "HPA054979: AB_2682661, HPA071815: AB_2686453" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (3.09e-1)" "unprognostic (1.99e-1)" "unprognostic (2.95e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (8.64e-3)" "unprognostic (6.61e-2)" "unprognostic (3.73e-1)" "unprognostic (3.47e-2)" "unprognostic (1.95e-1)" 19.7 17.1 16.0 5.4 16.1 23.3 19.9 14.5 25.3 14.7 13.9 16.4 5.9 12.0 2.7 11.4 11.9 7.7 15.0 15.8 14.9 14.5 15.2 12.1 12.5 15.4 15.2 13.6 8.6 3.0 3.1 6.5 15.8 10.7 6.0 7.1 12.2 6.7 29.0 10.5 13.2 7.3 15.1 12.1 14.6 6.8 15.5 5.3 10.3 16.9 7.3 15.0 12.0 17.2 37.4 33.5 3.3 3.3 11.2 23.4 0.0 24.3 29.1 36.6 30.7 43.1 16.2 33.3 19.9 26.6 10.1 16.0 15.6 19.5 39.6 15.5 42.2 28.0 20.3 46.7 38.8 40.4 41.5 23.8 37.0 15.3 33.3 12.6 16.1 4.8 33.9 21.2 28.1 35.6 12.0 110.1 24.2 23.0 59.1 14.1 28.8 29.4 30.3 1.0 10.8 15.9 33.5 13.9 19.1 1.9 10.4 13.6 18.4 8.7 9.6 6.0 24.7 7.3 5.0 12.8 31.2 58.8 43.4 7.0 53.6 19.1 13.3 32.7 14.5 35.2 19.2 16.1 29.7 33.3 20.5 14.7 3.5 10.6 30.2 33.8 20.4 31.8 16.0 16.1 14.5 25.3 15.8 14.9 15.4 15.2 15.8 15.1 15.5 17.2 156.9 25.6 40.4 3.9 83.9 84.5 96.6 82.4 62.0 33.9 89.9 80.4 40.3 48.6 52.6 73.5 43.8 156.3 69.5 116.4 148.7 53.6 12.1 37.3 34.2 96.0 12.2 50.9 6.2 80.7 154.7 66.4 30.5 33.4 61.6 53.9 94.2 147.1 115.6 18.5 6.6 100.8 44.7 113.7 111.5 24.0 67.1 91.9 97.8 9.4 134.1 174.9 87.6 4.0 11.1 83.5 157.5 54.5 55.8 100.3 190.7 182.3 49.2 126.8 78.9 99.4 68.8 45.9 91.5 57.8 97.7 94.0 70.3 108.1 88.3 95.4 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 7 "Inhibitory neurons: 83.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" 6.2 0.3 1.7 0.7 3.6 0.0 5.0 0.0 7.2 4.9 0.0 1.0 0.2 3.0 0.7 1.2 2.9 1.1 0.1 0.6 3.7 0.7 0.0 0.8 1.3 2.2 4.3 0.6 0.1 0.2 0.1 0.5 10.0 1.5 0.5 1.0 1.5 1.0 0.3 4.0 0.7 2.7 0.8 0.0 0.5 0.0 2.5 1.1 0.5 0.3 1.3 2.0 2.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.6 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.6 0.0 7.2 0.6 3.7 2.2 4.3 10.0 0.8 2.5 0.9 7.6 0.0 0.0 1.0 0.0 2.5 0.0 0.0 0.0 1.0 0.3 0.3 1.4 0.0 0.0 0.0 2.1 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 11.8 0.0 0.0 4.5 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 83.2 0.2 0.0 0.0 2.6 0.9 0.0 0.0 7.2 2.8 0.0 0.4 0.0 3.5 4.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 3.3 0.0 0.2 0.2 0.0 0.0 0.1 1.8 0.1 0.1 0.0 0.0 0.2 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 MRPL19 "KIAA0104, MRP-L15, RLX1, RPML15" ENSG00000115364 "Mitochondrial ribosomal protein L19" P49406 2 75646783-75690851 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 167.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046805, HPA056622" Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA046805: AB_2679816, HPA056622: AB_2683195" "unprognostic (9.24e-2)" "unprognostic (3.84e-2)" "prognostic favorable (7.39e-4)" "unprognostic (8.40e-2)" "unprognostic (1.59e-2)" "unprognostic (7.52e-3)" "unprognostic (5.75e-2)" "unprognostic (9.86e-2)" "unprognostic (6.21e-3)" "unprognostic (9.71e-3)" "prognostic unfavorable (1.97e-5)" "unprognostic (2.42e-1)" "unprognostic (3.67e-2)" "unprognostic (1.55e-1)" "unprognostic (3.30e-1)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" 31.3 30.1 21.8 18.9 27.4 13.9 28.6 26.5 23.5 29.1 14.8 27.8 23.7 21.7 25.2 25.0 18.1 20.7 35.0 18.8 26.7 56.0 63.7 17.8 20.3 23.4 24.4 17.4 23.6 45.2 12.2 25.7 25.4 21.6 30.9 19.3 24.1 25.1 66.4 23.9 19.9 29.0 26.8 16.9 18.4 16.5 24.9 24.3 36.9 44.8 25.1 24.5 15.1 32.5 100.7 57.5 53.3 48.3 57.0 68.1 75.6 63.4 57.0 78.5 62.2 88.5 40.6 56.5 62.1 69.2 73.8 69.5 83.7 95.8 117.8 63.2 72.4 77.4 44.4 114.3 61.0 82.9 44.5 45.6 72.4 79.7 72.3 49.6 84.1 60.8 86.4 32.3 78.5 61.9 76.1 64.9 69.9 102.9 65.2 94.5 116.5 74.5 134.1 61.9 58.8 50.2 62.2 71.2 72.4 53.3 61.1 32.8 57.0 68.3 75.4 61.2 94.6 33.3 53.8 47.1 53.9 81.0 61.1 17.7 20.2 14.2 22.1 26.8 25.1 26.8 22.7 23.8 29.7 22.7 19.9 24.6 1.4 24.4 24.9 35.0 26.5 17.2 21.8 27.4 26.5 23.5 18.8 26.7 23.4 24.4 25.4 26.8 24.9 32.5 31.8 19.2 29.6 10.7 27.4 29.1 28.6 77.8 21.1 38.3 32.4 29.5 40.2 25.8 49.4 49.7 52.1 90.3 26.3 24.0 125.2 88.7 27.6 42.7 48.4 27.7 27.6 32.8 13.9 61.1 87.3 33.7 36.7 50.3 19.0 35.8 27.1 67.6 47.3 48.8 14.3 36.5 44.7 14.6 17.0 11.2 35.4 23.7 33.8 12.2 35.0 39.6 34.0 15.1 20.0 53.6 27.7 36.5 36.5 36.1 36.5 167.7 32.8 50.9 19.7 31.4 38.1 55.5 17.6 44.3 28.3 57.7 25.3 62.2 50.7 35.6 GCFC2 "C2orf3, DNABF, GCF, TCF9" ENSG00000005436 "GC-rich sequence DNA-binding factor 2" P16383 2 75652000-75710985 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077882 Approved Supported Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA077882: AB_2686864" "unprognostic (1.98e-1)" "unprognostic (5.18e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (9.59e-4)" "unprognostic (5.67e-3)" "unprognostic (2.75e-1)" "unprognostic (2.34e-2)" "unprognostic (3.74e-2)" "unprognostic (8.80e-2)" "unprognostic (4.21e-2)" "unprognostic (1.63e-1)" "unprognostic (5.71e-2)" "unprognostic (3.20e-2)" "unprognostic (8.37e-2)" "unprognostic (1.04e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (6.07e-2)" 10.7 10.5 13.8 4.2 16.3 7.4 12.1 14.4 17.3 19.2 9.7 9.7 3.7 11.1 11.4 9.6 13.7 4.7 11.3 12.2 14.4 19.0 28.5 7.8 8.8 13.7 14.5 14.3 14.1 7.5 11.2 6.9 13.9 14.0 3.8 11.7 7.8 5.5 29.1 15.8 8.1 6.3 15.1 12.3 9.4 12.0 14.4 7.6 12.1 9.1 6.5 9.0 10.4 17.3 14.4 13.9 9.8 11.6 5.3 6.7 12.7 9.5 7.7 9.7 9.2 16.7 10.3 14.2 13.4 6.5 11.9 5.5 11.9 6.5 13.0 20.9 25.5 10.9 13.6 44.9 8.3 18.8 10.2 7.2 8.2 4.8 14.5 11.0 11.6 17.6 16.5 8.2 9.3 11.3 19.6 31.8 15.5 10.5 15.3 22.8 20.1 34.6 16.3 15.7 18.0 22.6 12.8 14.5 16.2 6.9 10.8 10.6 12.6 9.3 12.2 13.4 19.3 9.5 17.7 10.8 9.2 11.7 20.7 0.6 8.1 3.8 10.4 5.7 11.9 18.2 9.7 12.1 9.4 12.6 14.3 13.2 0.4 5.4 9.6 13.3 11.5 8.9 13.8 16.3 14.4 17.3 12.2 14.4 13.7 14.5 13.9 15.1 14.4 17.3 11.6 16.0 11.2 49.6 15.7 27.8 20.5 14.0 21.6 11.2 14.4 13.5 22.4 17.2 20.2 12.9 0.0 36.7 14.8 7.3 21.5 16.0 31.5 11.4 18.0 15.0 16.2 12.0 60.8 19.0 23.5 21.9 8.2 8.7 13.9 15.6 13.2 24.9 12.5 16.8 51.7 7.5 8.2 13.9 12.0 75.4 16.8 8.8 14.2 20.6 7.1 10.6 16.5 75.9 75.9 13.8 7.8 9.8 11.3 18.0 6.2 19.3 15.1 9.1 13.1 20.2 13.5 15.5 22.7 16.5 24.7 23.7 13.3 17.4 10.6 16.8 LRRTM4 FLJ12568 ENSG00000176204 "Leucine rich repeat transmembrane neuronal 4" Q86VH4 2 76747685-77593319 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 17.6;retina: 6.8" "Group enriched" "Detected in some" 16 "Excitatory neurons: 3972.6;Inhibitory neurons: 2310.6;Oligodendrocyte precursor cells: 3758.4" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 10 "Karpas-707: 125.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (2.00e-1)" "unprognostic (4.40e-2)" "unprognostic (3.13e-1)" "unprognostic (4.72e-4)" "unprognostic (7.20e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-2)" "unprognostic (9.15e-2)" "unprognostic (3.93e-1)" "unprognostic (5.84e-2)" "unprognostic (4.22e-2)" "unprognostic (1.40e-1)" "unprognostic (2.64e-1)" "unprognostic (5.77e-3)" "unprognostic (3.54e-2)" "unprognostic (7.99e-2)" 0.4 0.6 5.8 0.3 11.4 1.7 0.2 0.1 17.6 0.4 0.0 0.5 0.8 0.4 1.5 0.8 0.2 0.7 0.1 13.5 1.6 0.2 1.3 0.8 0.4 0.2 4.1 0.6 0.5 0.0 1.0 0.9 1.2 0.6 0.5 6.8 0.9 1.5 1.6 0.8 0.5 0.3 0.0 0.5 0.6 0.3 0.0 0.1 0.7 0.3 0.2 0.3 0.5 14.5 1.4 1.7 0.9 0.8 0.0 0.0 0.9 0.3 0.0 0.0 0.0 2.1 0.5 1.0 2.2 0.8 0.7 0.8 0.2 0.0 0.3 0.8 2.5 0.5 4.8 3.1 0.4 1.3 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.5 125.8 0.0 2.8 0.5 0.7 12.2 0.2 1.2 0.5 0.1 2.6 0.0 4.1 3.7 1.4 0.8 0.7 0.8 2.0 1.4 0.9 0.0 2.9 3.7 0.1 0.2 0.0 2.4 0.1 2.8 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.2 0.1 0.0 0.1 0.0 5.8 11.4 0.1 17.6 13.5 1.6 0.2 4.1 1.2 0.0 0.0 14.5 0.0 0.0 0.5 208.6 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.3 0.3 0.0 0.0 0.0 4.2 0.1 0.0 0.0 0.0 0.0 1.1 0.4 0.2 0.4 0.0 0.0 3972.6 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 2310.6 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 84.3 0.0 2.8 0.0 3758.4 176.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.7 2.3 6.6 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 REG3G "LPPM429, PAP1B, UNQ429" ENSG00000143954 "Regenerating family member 3 gamma" Q6UW15 2 79025686-79028505 "Predicted secreted proteins" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "pancreas: 3517.1" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 184.9;Pancreatic endocrine cells: 53.5;Proximal enterocytes: 39.4" "Cancer enriched" "Detected in many" 13 "pancreatic cancer: 71.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047894, HPA048334, HPA060705" Uncertain Approved Cytosol "Secreted to digestive system" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (3.29e-1)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (8.82e-2)" "unprognostic (7.20e-3)" "unprognostic (5.64e-2)" 1.0 46.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 2.4 0.1 165.7 0.3 0.3 0.0 0.2 0.0 0.0 6.0 0.4 0.1 0.0 0.0 0.0 0.2 3517.1 0.0 0.3 1.1 0.0 0.1 0.0 0.0 0.3 1.3 0.2 0.1 37.0 1.5 0.0 0.2 0.4 57.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.7 0.0 0.0 0.1 0.0 0.0 0.0 184.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 6.2 0.6 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 53.5 0.0 0.7 0.0 0.4 39.4 2.2 0.0 0.0 0.0 0.0 0.2 1.3 1.2 0.0 0.0 0.0 0.0 0.9 5.4 0.0 REG1B "PSPS2, REGH, REGI-BETA, REGL" ENSG00000172023 "Regenerating family member 1 beta" P48304 2 79085023-79088019 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 39745.3" "Cell type enriched" "Detected in some" 4 "Exocrine glandular cells: 36125.0" "Cancer enriched" "Detected in some" 5 "pancreatic cancer: 201.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 4.1;RPMI-8226: 3.0;U-2 OS: 15.7;U-251 MG: 3.9;U-266/84: 3.8" "HPA045549, HPA045579" Supported "Secreted to digestive system" NA NA 32000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (4.08e-1)" "unprognostic (1.09e-1)" "unprognostic (3.51e-3)" "unprognostic (9.20e-2)" 14.6 2.1 0.0 35.8 0.0 9.8 3.3 0.0 0.1 3.9 0.0 17.3 738.0 2.0 0.0 3.5 2.1 0.4 3.3 0.0 0.0 2.6 5.5 1.7 1.7 0.0 0.0 2.1 39745.3 0.0 3.1 0.1 0.0 2.0 108.1 0.0 3.1 0.0 1.6 16.1 2754.3 112.1 0.0 3.2 5.0 1.5 0.0 0.0 1.7 0.0 0.0 1.3 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.1 3.9 0.0 3.8 1.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 86.7 0.0 0.0 0.0 3.3 1.8 0.0 0.0 36125.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.6 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 178.3 0.0 0.0 0.0 0.0 7978.5 174.7 0.0 0.0 0.0 3101.3 0.1 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 178.8 0.0 REG1A "PSP, PSPS, PSPS1, PTP, REG" ENSG00000115386 "Regenerating family member 1 alpha" P05451 2 79120362-79123409 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "pancreas: 103906.5" "Cell type enriched" "Detected in some" 5 "Exocrine glandular cells: 115721.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 1268.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.3;EFO-21: 18.3;HDLM-2: 15.2;NB-4: 11.0;OE19: 10.7;RPMI-8226: 32.5;SH-SY5Y: 12.5;U-2 OS: 31.1;U-251 MG: 10.8;U-266/84: 13.3" "CAB025138, HPA045549, HPA045579" Enhanced "Secreted to digestive system" NA NA 68000000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "CAB025138: , HPA045549: AB_2679365, HPA045579: AB_2679374" "unprognostic (1.89e-1)" "unprognostic (2.91e-2)" "unprognostic (3.39e-1)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.52e-2)" "unprognostic (3.54e-3)" "unprognostic (5.53e-2)" "unprognostic (5.54e-2)" 26.8 5.8 0.0 198.7 0.0 20.7 9.9 0.0 0.0 10.9 0.0 96.5 7597.3 5.3 0.0 9.3 6.4 96.6 10.2 0.0 0.0 93.0 15.9 4.5 7.5 0.0 0.0 25.6 103906.5 0.0 8.5 3.4 0.0 6.1 283.0 0.0 9.4 0.1 4.3 28.1 5638.4 178.1 0.0 8.5 945.9 3.9 0.0 0.0 4.0 0.0 0.4 3.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.5 10.7 0.0 0.0 0.0 32.5 0.0 0.0 1.4 12.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 31.1 2.0 10.8 0.0 13.3 5.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.2 0.0 0.0 0.0 0.0 0.0 25.5 1.9 1549.8 0.1 0.1 0.0 12.7 5.3 0.0 0.0 115721.8 0.0 0.9 692.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1813.1 0.0 0.0 0.0 0.1 0.0 17.0 0.0 0.0 507.5 0.0 0.0 0.0 0.0 22774.8 732.4 0.0 0.2 0.0 5100.1 20.8 0.0 0.0 0.0 0.0 51.7 0.0 0.4 0.0 0.0 0.0 0.6 0.0 5419.7 0.0 REG3A "HIP, PAP, PAP1, PBCGF, REG-III, REG3" ENSG00000172016 "Regenerating family member 3 alpha" Q06141 2 79157003-79159753 "Plasma proteins, Predicted secreted proteins, Transporters" "Acute phase, Inflammatory response" Antimicrobial "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 61 "intestine: 6743.6;pancreas: 12212.2" "Group enriched" "Detected in some" 11 "Exocrine glandular cells: 1988.6;Pancreatic endocrine cells: 5382.1" "Cancer enhanced" "Detected in some" "pancreatic cancer: 710.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 17.6;EFO-21: 15.8;HDLM-2: 15.4;NB-4: 17.7;RPMI-8226: 24.6;SH-SY5Y: 14.6;U-2 OS: 28.5;U-251 MG: 11.0;U-266/84: 15.1" "HPA047894, HPA048334, HPA060705" Supported Approved Cytosol "Secreted to digestive system" NA NA 23000000 "Cluster 25: Pancreas - Digestion" "Cluster 24: NB-4 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA047894: AB_2680202, HPA048334: AB_2680363, HPA060705: AB_2684346" "unprognostic (2.43e-2)" "unprognostic (2.12e-1)" "unprognostic (3.62e-2)" "unprognostic (1.42e-1)" 18.5 10.0 0.0 13.3 0.0 0.2 0.6 0.0 0.0 0.3 0.0 19.2 5180.0 2.9 0.0 1.4 0.2 24.9 1.0 0.0 0.0 2.6 2.0 0.5 4.9 0.0 0.0 0.9 12212.2 0.0 2.1 0.1 0.0 0.5 0.0 0.0 2.1 0.0 0.6 0.4 6743.6 0.2 0.0 1.3 156.5 0.9 0.0 0.0 0.6 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.1 0.4 0.0 0.0 0.0 24.6 0.0 0.0 1.8 14.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.5 5.4 11.0 0.0 15.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 152.8 7.7 0.0 0.0 3.0 0.0 0.0 0.0 1988.6 0.0 0.0 189.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.2 0.0 0.0 0.0 6.8 0.0 1.4 0.0 0.0 55.8 0.0 0.0 0.0 0.0 5382.1 32.5 0.0 0.2 0.0 215.0 0.0 0.0 0.0 0.0 0.0 16.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 315.9 0.0 CTNNA2 "CAP-R, CT114" ENSG00000066032 "Catenin alpha 2" P26232 2 79185231-80648861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Differentiation" "Developmental protein" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 99.0;epididymis: 67.0;retina: 80.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3673.8;Early spermatids: 560.8;Excitatory neurons: 1358.5;Inhibitory neurons: 1056.9;Oligodendrocyte precursor cells: 1304.4" "Group enriched" "Detected in some" 7 "endometrial cancer: 3.9;glioma: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 96 "basophil: 55.3" "Lineage enriched" "Detected in single" 553 "granulocytes: 55.3" "Cell line enhanced" "Detected in some" "AF22: 7.1;Karpas-707: 8.2;NTERA-2: 6.7;SCLC-21H: 3.8;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" CAB037175 Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "CAB037175: AB_476883" "unprognostic (9.15e-2)" "unprognostic (2.26e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (4.04e-1)" "unprognostic (3.17e-2)" "unprognostic (5.62e-2)" "unprognostic (7.96e-3)" "unprognostic (8.76e-2)" "unprognostic (2.27e-4)" "unprognostic (7.80e-2)" "unprognostic (8.44e-4)" "unprognostic (1.73e-4)" "unprognostic (2.83e-1)" 0.1 4.7 74.1 0.5 82.5 0.1 0.0 51.8 99.0 0.4 28.5 1.9 0.3 3.3 67.0 0.2 1.9 0.2 0.2 78.8 59.3 0.1 0.1 0.0 0.0 47.0 71.2 0.1 0.8 0.0 7.1 0.0 50.8 1.0 0.9 80.4 0.2 0.7 0.2 0.1 0.7 0.5 36.6 0.0 1.1 17.4 78.9 0.0 0.0 0.0 0.0 0.1 0.4 62.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 6.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 3.8 10.7 0.0 0.0 0.5 1.0 0.0 0.6 0.0 0.4 0.7 0.2 0.0 2.3 0.0 0.0 2.7 0.0 2.0 55.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 74.1 82.5 51.8 99.0 78.8 59.3 47.0 71.2 50.8 36.6 78.9 62.0 0.0 0.0 0.0 3673.8 0.0 0.0 0.0 0.0 0.0 17.2 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 560.8 12.9 7.0 0.5 0.0 0.0 1358.5 0.0 0.0 0.1 0.0 34.3 0.0 4.7 0.0 0.0 0.0 5.0 1056.9 0.0 0.0 0.0 0.0 144.4 2.5 0.5 0.0 187.4 0.0 112.1 0.0 1304.4 230.7 0.3 0.0 3.0 0.0 0.0 0.0 0.2 0.0 5.0 0.0 0.0 0.2 10.3 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LRRTM1 FLJ32082 ENSG00000162951 "Leucine rich repeat transmembrane neuronal 1" Q86UE6 2 80288351-80304752 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.4;salivary gland: 12.8" "Group enriched" "Detected in some" 4 "Endometrial stromal cells: 4.8;Excitatory neurons: 7.2;Inhibitory neurons: 13.2;Oligodendrocyte precursor cells: 10.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 11 "endometrial cancer: 8.8;ovarian cancer: 16.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046607, HPA062660" Approved Approved "Golgi apparatus" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "HPA046607: , HPA062660: AB_2684824" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (5.63e-2)" "unprognostic (6.67e-2)" "unprognostic (4.35e-1)" "unprognostic (2.66e-1)" "unprognostic (8.16e-2)" "unprognostic (6.03e-3)" "unprognostic (7.10e-4)" "unprognostic (3.16e-2)" "unprognostic (1.90e-1)" "unprognostic (4.96e-4)" 0.5 0.9 6.4 0.3 13.4 0.0 0.1 0.0 10.0 2.2 0.0 3.7 0.6 0.6 0.3 0.3 1.2 0.2 1.3 16.3 5.2 0.3 0.4 0.1 0.0 0.9 9.4 0.3 0.1 0.0 1.9 0.0 2.0 1.0 0.3 0.4 12.8 1.2 0.0 0.1 1.3 0.3 0.2 0.0 0.7 0.2 22.4 0.0 1.6 0.1 0.0 0.6 0.8 4.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 13.4 0.0 10.0 16.3 5.2 0.9 9.4 2.0 0.2 22.4 4.6 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 1.3 1.0 4.8 0.3 0.0 0.0 7.2 0.7 0.0 0.1 0.0 0.9 0.0 0.4 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 10.6 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 6.6 0.0 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 DNAH6 "Dnahc6, DNHL1, FLJ37357, HL-2" ENSG00000115423 "Dynein axonemal heavy chain 6" Q9C0G6 2 84516455-84819589 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;choroid plexus: 12.1;fallopian tube: 5.4" "Cell type enhanced" "Detected in many" "Early spermatids: 77.5;Endometrial ciliated cells: 98.2;Excitatory neurons: 94.2;Respiratory ciliated cells: 143.6" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "OE19: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA036391, HPA061401" Enhanced NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA036391: AB_10672220, HPA061401: " "unprognostic (4.87e-2)" "unprognostic (4.60e-2)" "unprognostic (1.04e-1)" "unprognostic (1.40e-2)" "unprognostic (1.42e-1)" "unprognostic (9.72e-2)" "unprognostic (1.67e-1)" "unprognostic (6.43e-2)" "unprognostic (6.06e-2)" "unprognostic (3.46e-1)" "unprognostic (8.11e-8)" "unprognostic (2.04e-1)" "unprognostic (2.33e-1)" "unprognostic (2.11e-2)" "unprognostic (1.87e-1)" "unprognostic (1.80e-2)" "unprognostic (5.97e-2)" 0.3 0.2 1.4 0.1 2.4 0.0 0.4 0.0 1.7 0.2 12.1 0.1 0.0 0.5 1.2 0.0 5.4 0.1 0.0 1.5 1.1 0.4 1.1 0.8 0.1 4.4 4.6 0.3 0.2 1.6 0.4 0.0 2.4 0.1 0.2 0.8 0.0 0.2 0.0 0.0 0.1 0.1 2.7 0.0 0.5 2.7 1.6 0.5 1.2 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.4 2.4 0.0 1.7 1.5 1.1 4.4 4.6 2.4 2.7 1.6 1.6 0.6 6.4 4.1 18.6 0.6 0.1 2.2 5.4 0.0 0.8 1.4 1.8 1.2 1.5 13.7 0.0 2.1 0.9 0.3 0.3 0.0 0.3 77.5 98.2 1.5 0.9 0.0 0.4 94.2 0.9 0.2 2.7 4.1 3.0 0.0 1.6 0.0 6.9 0.1 0.0 28.2 1.0 10.2 0.3 0.2 25.0 0.6 0.3 1.8 9.4 0.0 2.0 0.0 5.5 13.7 0.3 0.3 0.7 0.1 1.0 0.2 1.0 143.6 4.8 0.0 2.1 1.7 23.3 5.1 0.0 0.0 0.3 1.3 0.3 1.1 0.3 TRABD2A "C2orf89, TIKI1" ENSG00000186854 "TraB domain containing 2A" Q86V40 2 84821650-84907008 "Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 42.7;lymphoid tissue: 11.4;ovary: 26.7" "Cell type enhanced" "Detected in many" "Early spermatids: 575.5;Granulosa cells: 108.7;Late spermatids: 326.8;Undifferentiated cells: 141.9" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 14.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 71.9" "Lineage enriched" "Detected in many" 18 "T-cells: 71.9" "Cell line enhanced" "Detected in many" "BEWO: 41.7;HDLM-2: 35.1;HSkMC: 22.3;hTEC/SVTERT24-B: 17.8;SiHa: 17.8" HPA045817 Approved "Intracellular and membrane" NA NA 18000 "Cluster 32: T-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "HPA045817: AB_2679460" "unprognostic (7.49e-3)" "unprognostic (3.35e-1)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (3.82e-5)" "unprognostic (2.46e-2)" "unprognostic (2.47e-1)" "unprognostic (1.31e-1)" "unprognostic (6.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.47e-4)" "unprognostic (4.29e-2)" "unprognostic (7.60e-2)" "unprognostic (1.41e-3)" "unprognostic (1.37e-1)" 2.5 0.4 2.1 8.9 2.1 3.7 2.2 0.3 3.4 0.3 0.3 40.0 4.2 0.2 0.7 0.3 0.8 0.5 0.3 1.9 1.5 0.6 1.0 2.8 11.4 0.3 2.7 26.7 0.1 2.1 0.3 0.9 0.3 0.2 42.7 0.0 0.5 0.1 0.1 1.0 10.7 2.8 0.4 3.8 1.1 0.4 3.8 8.1 0.4 0.6 7.8 0.7 0.4 1.6 1.3 1.1 0.4 0.2 12.4 13.4 41.7 2.0 3.3 5.8 10.8 0.5 4.7 0.0 0.5 6.5 10.8 0.0 2.8 0.6 8.6 35.1 0.7 0.0 8.4 0.0 1.5 0.1 0.0 22.3 0.0 17.8 8.1 1.3 0.0 0.3 0.0 0.1 0.8 0.0 0.1 0.1 1.1 2.3 0.9 0.3 0.7 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.2 0.3 0.0 0.2 0.3 5.8 0.8 0.0 2.1 4.0 0.0 0.1 5.3 3.5 0.0 0.0 0.3 0.0 8.5 0.3 10.5 0.7 33.6 12.4 1.8 3.9 71.9 46.1 1.3 3.9 0.2 1.6 23.5 13.2 2.1 2.1 0.3 3.4 1.9 1.5 0.3 2.7 0.3 0.4 3.8 1.6 9.0 3.2 11.0 0.0 7.8 1.0 0.6 0.6 0.0 1.1 1.4 0.4 85.4 0.0 0.9 0.0 0.0 9.4 4.6 51.1 0.0 0.1 575.5 4.3 0.6 7.5 12.7 0.8 10.6 0.9 41.5 6.1 2.6 1.9 2.5 108.7 2.2 0.1 2.6 0.0 0.7 67.9 0.0 1.3 6.6 326.8 5.0 4.6 3.6 3.7 12.6 0.0 3.1 1.0 0.7 0.6 73.8 2.6 5.4 0.5 17.4 1.2 1.7 0.1 6.6 0.9 7.3 3.5 5.6 0.4 0.6 4.4 29.7 0.2 141.9 0.5 TMSB10 TB10 ENSG00000034510 "Thymosin beta 10" P63313 2 84905656-84906671 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 16401.2;Pancreatic endocrine cells: 17155.8;Paneth cells: 14859.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (3.60e-1)" "unprognostic (4.52e-2)" "unprognostic (7.03e-2)" "unprognostic (6.19e-3)" "unprognostic (2.61e-2)" "unprognostic (4.73e-2)" "unprognostic (1.17e-3)" "unprognostic (3.26e-3)" "unprognostic (2.99e-2)" "unprognostic (2.76e-3)" "unprognostic (2.20e-3)" "unprognostic (7.24e-2)" "prognostic unfavorable (8.49e-7)" "unprognostic (1.28e-1)" "unprognostic (2.83e-1)" "prognostic favorable (4.97e-5)" "unprognostic (3.16e-2)" 2615.3 793.1 2689.6 2321.3 2793.9 2151.3 2237.7 2475.2 3465.2 1864.6 2537.0 3101.8 1043.8 1084.7 3568.4 2055.5 934.6 1678.7 1531.9 2920.3 2746.7 1511.5 753.6 2686.1 3289.8 2618.9 2602.9 3000.9 773.5 422.1 667.6 1867.9 2664.9 930.2 2727.6 164.6 1424.6 625.1 425.8 1055.5 2153.5 1746.1 2610.3 2314.6 1225.6 726.8 2697.0 3880.9 1050.7 1001.2 2614.6 2634.4 1379.7 2735.7 4179.1 4879.7 4367.9 2450.2 5716.2 11866.8 2267.0 6207.1 8860.4 6955.7 8321.0 3926.0 6366.0 2141.4 4396.8 12906.3 4202.7 1577.1 1269.9 14656.3 7495.5 7204.8 1203.6 969.6 3115.0 3298.9 3576.8 922.9 869.4 10328.2 7273.4 8459.2 4525.9 7545.5 10791.9 1117.3 371.3 3548.2 11749.0 3349.8 3276.5 3837.4 1546.6 11202.2 4994.4 2449.8 6704.6 1757.5 10528.0 804.1 2320.1 2096.0 4162.9 3586.1 5349.0 3999.0 1082.4 1596.4 10174.1 5455.4 3862.3 5018.4 6361.9 700.7 1262.7 1992.4 9124.5 3943.6 4390.2 10530.4 18217.1 11082.3 9181.1 15870.9 5713.8 16178.6 13824.2 9777.6 19825.0 16572.3 14273.3 12095.8 2524.9 7907.9 13950.4 11840.7 24168.9 49770.5 2689.6 2793.9 2475.2 3465.2 2920.3 2746.7 2618.9 2602.9 2664.9 2610.3 2697.0 2735.7 8162.0 1189.1 1204.5 38.5 3447.0 2152.8 1551.7 6421.9 1175.8 28.5 3535.0 3219.3 162.5 1265.3 2597.6 1923.8 14.6 4025.2 4651.7 3067.5 1013.5 7642.4 124.4 5122.3 2856.2 5762.7 2298.3 1028.8 73.5 7323.5 12194.2 3030.8 2692.7 6575.0 1398.4 7787.7 3750.9 382.6 6521.7 18.5 20.9 5508.5 2370.1 9660.7 10699.9 381.9 1523.5 7008.1 3317.3 122.7 16401.2 56.4 5596.3 24.1 36.4 17155.8 14859.3 1188.2 2808.9 2936.5 10487.4 2720.9 1187.9 103.8 1012.4 1252.2 3039.8 84.8 210.0 2596.4 1958.8 1560.0 4498.5 2022.2 6534.2 3048.3 KCMF1 "DEBT91, DKFZP434L1021, PCMF, ZZZ1" ENSG00000176407 "Potassium channel modulatory factor 1" Q9P0J7 2 84971093-85059472 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030383, HPA030384" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Nucleoplasm "HPA030383: AB_10599977, HPA030384: AB_10601230" "unprognostic (8.01e-2)" "unprognostic (1.98e-2)" "unprognostic (9.95e-2)" "unprognostic (7.42e-3)" "unprognostic (1.24e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (5.68e-3)" "unprognostic (1.43e-1)" "unprognostic (9.81e-2)" "prognostic unfavorable (6.10e-5)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.18e-6)" "unprognostic (6.11e-2)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (1.01e-1)" 39.7 24.0 23.4 34.0 22.2 60.8 33.8 21.3 30.2 28.1 20.4 46.7 34.8 29.2 39.7 58.3 27.6 29.5 44.1 25.6 24.1 33.1 45.0 31.9 36.1 25.2 26.5 24.7 80.0 39.2 20.8 33.0 24.8 27.9 46.4 32.4 36.8 31.8 140.0 35.2 36.2 40.5 24.8 28.3 33.5 69.0 27.3 37.0 40.4 71.7 52.3 37.7 36.1 22.1 102.3 76.4 66.7 51.8 69.0 66.2 114.5 106.0 96.0 97.4 64.6 93.8 104.5 110.9 107.2 141.6 97.0 65.1 52.7 100.6 127.8 87.6 37.9 69.8 55.9 97.3 134.7 77.9 63.9 69.0 155.7 95.7 262.5 86.4 74.7 57.2 71.3 83.1 98.4 91.5 76.9 42.6 74.9 125.5 64.1 55.4 94.7 68.5 88.3 85.8 64.8 48.9 61.0 76.0 101.8 76.4 35.3 48.1 66.2 98.9 99.2 93.5 111.8 99.1 130.9 110.4 74.5 55.7 75.8 3.1 1.6 5.4 2.7 1.4 2.1 2.3 1.9 2.0 1.4 3.1 1.6 1.8 4.5 1.9 2.2 2.6 6.0 1.0 23.4 22.2 21.3 30.2 25.6 24.1 25.2 26.5 24.8 24.8 27.3 22.1 45.5 32.1 26.6 25.5 29.6 70.9 92.9 32.7 24.5 31.8 42.8 34.3 51.4 21.5 33.2 12.9 14.6 23.6 42.0 56.2 25.4 34.8 85.2 55.3 33.8 33.1 19.2 29.0 47.9 53.4 32.0 31.9 18.8 80.5 17.7 30.9 24.3 32.9 20.1 72.3 47.4 29.0 20.3 33.3 61.1 127.7 25.7 34.7 26.6 51.5 36.8 37.5 21.6 45.8 36.6 61.2 40.8 29.0 27.6 107.6 44.8 30.7 22.5 27.5 26.3 48.2 47.2 44.9 24.6 34.4 79.0 40.8 32.1 27.1 33.7 135.5 TCF7L1 TCF3 ENSG00000152284 "Transcription factor 7 like 1" Q9HCS4 2 85133392-85310387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 49.2;Astrocytes: 76.4;Leydig cells: 65.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 43.3;NTERA-2: 99.0;RH-30: 44.7;T-47d: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071298 Supported Nucleoplasm,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA071298: AB_2686383" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (3.64e-3)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.05e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (6.16e-5)" "unprognostic (1.79e-2)" "unprognostic (3.59e-3)" "unprognostic (2.73e-1)" "unprognostic (5.17e-3)" "unprognostic (1.69e-1)" "prognostic unfavorable (2.06e-4)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.70e-1)" "unprognostic (3.52e-2)" "prognostic unfavorable (5.38e-4)" 37.8 5.3 7.5 4.0 9.9 3.7 33.4 7.8 6.4 33.1 13.8 27.6 4.3 25.9 6.7 10.0 20.1 7.2 20.3 6.9 7.7 15.7 12.5 17.8 5.9 10.8 13.0 27.5 4.5 7.0 8.9 5.2 6.9 20.0 4.1 1.7 13.1 14.5 15.0 14.6 12.2 13.0 7.4 11.8 10.7 9.1 10.0 5.8 30.6 7.9 3.5 18.3 24.1 6.7 2.1 1.5 33.5 25.8 12.6 2.6 20.3 2.5 8.5 5.8 5.3 5.2 2.0 0.7 4.0 5.6 6.4 4.7 25.9 43.3 4.0 1.8 4.1 0.7 2.1 2.3 1.2 0.3 4.9 2.1 7.7 0.6 1.4 2.6 11.2 1.3 0.5 1.3 6.8 1.6 0.2 1.6 99.0 1.3 0.9 0.6 44.7 0.5 2.7 3.7 1.0 10.4 4.0 17.1 1.3 25.9 44.3 0.9 12.1 6.5 9.2 0.4 3.3 1.1 0.3 0.4 0.2 1.0 5.2 5.1 0.5 1.1 0.5 0.4 0.7 1.1 0.6 0.7 0.2 1.5 0.7 0.9 1.3 0.9 0.5 0.9 0.6 0.1 7.5 9.9 7.8 6.4 6.9 7.7 10.8 13.0 6.9 7.4 10.0 6.7 49.2 6.4 37.3 76.4 1.0 6.0 14.4 12.9 15.9 0.2 20.0 33.1 9.1 5.7 10.5 16.5 0.0 6.3 0.8 0.3 0.0 3.7 28.2 9.4 17.5 31.4 0.0 0.0 1.1 5.6 4.0 28.9 0.5 16.0 5.1 39.4 45.7 6.7 1.7 0.0 2.2 2.9 8.2 9.1 8.3 5.4 65.3 2.2 3.6 22.5 1.0 4.9 0.0 32.2 1.5 1.1 1.6 28.6 1.4 10.8 5.0 2.2 7.7 0.2 6.6 24.9 28.9 1.9 9.3 3.4 3.4 1.4 1.2 2.9 2.1 2.4 TGOLN2 "TGN38, TGN46, TGN48, TGN51, TTGN2" ENSG00000152291 "Trans-golgi network protein 2" O43493 2 85318020-85328296 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011489, HPA012609, HPA012723" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Nucleoplasm "CAB011489: AB_443302, HPA012609: AB_1857976, HPA012723: AB_1857975" "unprognostic (3.03e-2)" "unprognostic (1.82e-2)" "unprognostic (2.35e-1)" "unprognostic (4.39e-2)" "unprognostic (3.90e-2)" "unprognostic (2.66e-1)" "unprognostic (5.50e-3)" "unprognostic (2.49e-1)" "unprognostic (2.98e-1)" "unprognostic (1.52e-2)" "unprognostic (5.19e-2)" "unprognostic (2.72e-2)" "unprognostic (6.30e-2)" "unprognostic (2.83e-2)" "unprognostic (3.22e-2)" "unprognostic (2.04e-2)" "unprognostic (5.37e-2)" 70.0 67.5 37.5 82.6 42.1 129.9 58.3 38.5 44.0 63.5 32.2 85.8 110.6 62.0 60.9 41.1 65.1 75.7 63.5 39.6 45.3 120.8 136.5 86.8 73.9 45.5 43.4 61.3 56.0 67.1 26.9 76.6 44.9 66.9 102.3 31.8 59.8 62.5 34.7 40.1 111.9 74.0 40.4 83.2 74.8 37.1 45.1 65.2 91.3 46.2 66.1 61.4 41.0 50.0 46.5 116.4 51.8 68.6 124.0 129.0 120.7 144.1 172.2 98.5 78.5 100.6 142.2 60.6 108.3 207.1 132.9 76.4 37.8 71.9 161.8 96.5 36.7 87.2 41.3 113.3 67.1 173.0 189.5 96.2 45.2 125.5 76.1 152.1 144.4 49.5 50.9 94.1 147.1 43.9 54.0 86.3 46.0 109.3 47.5 55.4 193.1 45.6 104.8 73.2 47.4 40.5 127.2 95.5 83.6 61.7 50.7 77.0 155.7 205.5 73.9 158.6 173.5 58.7 81.9 58.1 152.3 131.1 137.3 62.6 78.0 68.5 32.4 73.3 25.0 25.0 23.8 22.4 41.5 24.4 24.3 23.6 96.3 25.1 103.5 15.9 20.9 75.6 37.5 42.1 38.5 44.0 39.6 45.3 45.5 43.4 44.9 40.4 45.1 50.0 104.4 102.5 96.4 22.5 89.7 38.2 57.1 72.5 43.9 53.3 89.2 56.4 64.3 150.2 84.2 180.3 39.6 59.4 116.9 216.1 9.8 92.7 6.0 86.3 89.5 91.7 89.5 39.5 29.5 93.2 80.9 87.5 64.7 105.7 158.8 70.5 86.7 245.0 113.0 208.6 37.9 99.0 52.9 187.1 85.3 7.8 49.4 145.6 60.5 33.7 126.9 47.8 95.8 25.1 50.6 101.6 121.8 69.2 74.0 62.8 211.2 82.8 111.4 36.5 65.7 85.0 65.8 36.1 37.1 32.6 34.9 44.6 91.1 61.9 100.3 70.8 RETSAT FLJ20296 ENSG00000042445 "Retinol saturase" Q6NUM9 2 85341955-85354531 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 247.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 264.9;Proximal enterocytes: 249.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007961, HPA046513" Uncertain Uncertain Nucleoli NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoli "HPA007961: AB_1079802, HPA046513: AB_2679680" "unprognostic (6.17e-2)" "unprognostic (1.02e-1)" "unprognostic (1.29e-1)" "unprognostic (5.84e-3)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" "prognostic favorable (4.23e-4)" "unprognostic (1.89e-1)" "unprognostic (2.16e-1)" "unprognostic (3.59e-2)" "unprognostic (1.77e-2)" "unprognostic (1.59e-1)" "prognostic favorable (1.95e-10)" "unprognostic (2.73e-2)" "unprognostic (5.34e-1)" "unprognostic (8.24e-3)" "unprognostic (9.90e-2)" 247.0 52.3 16.5 17.6 20.9 3.8 63.9 19.8 15.8 18.9 27.3 89.6 167.0 16.0 38.4 36.9 15.7 32.0 20.3 14.9 20.0 54.9 115.9 24.6 11.7 21.0 20.0 17.0 37.5 36.9 7.2 11.6 20.0 32.5 73.5 9.5 27.8 23.6 68.3 48.8 142.4 22.0 19.2 11.7 60.9 14.6 19.9 12.2 47.4 55.1 19.9 19.0 23.7 23.7 52.7 30.1 16.8 40.0 197.8 37.0 22.1 37.8 46.5 22.5 31.5 20.9 36.2 18.5 30.3 29.6 17.9 42.6 22.9 65.6 21.6 22.8 15.9 9.0 23.5 50.6 47.6 17.9 19.3 48.6 87.2 28.7 38.1 51.4 37.6 15.4 9.7 43.1 42.0 11.0 12.5 9.0 5.6 52.6 36.2 8.1 33.7 23.9 39.1 30.1 8.3 13.8 31.4 59.9 101.8 11.2 28.2 2.9 30.0 25.3 13.8 23.5 19.9 23.0 22.9 7.2 30.9 20.5 17.6 0.0 3.8 1.8 4.8 4.0 6.2 2.6 3.5 6.0 4.0 1.5 2.5 2.5 3.7 5.1 8.7 2.7 4.2 3.4 16.5 20.9 19.8 15.8 14.9 20.0 21.0 20.0 20.0 19.2 19.9 23.7 7.3 28.9 29.6 5.9 4.5 11.3 10.8 18.6 12.5 3.7 13.0 7.9 21.7 21.5 15.5 12.9 18.8 10.9 4.3 264.9 0.0 23.7 27.6 9.7 6.8 9.7 10.8 2.5 5.7 36.1 6.5 9.0 56.1 16.6 10.8 5.5 7.5 54.7 9.9 11.8 4.5 45.0 8.2 10.4 8.6 60.0 14.6 7.4 30.2 7.5 8.3 8.3 10.3 6.6 12.1 32.7 79.2 12.4 10.3 11.8 249.9 17.8 11.9 4.9 0.0 7.7 8.8 2.9 3.1 24.9 14.9 8.5 7.7 9.9 56.6 9.8 ELMOD3 "DFNB88, FLJ21977, RBED1, RBM29" ENSG00000115459 "ELMO domain containing 3" Q96FG2 2 85354394-85391752 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012126 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Mitochondria" "HPA012126: AB_1848130" "unprognostic (1.90e-1)" "unprognostic (9.80e-3)" "unprognostic (1.42e-3)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (1.60e-2)" "unprognostic (1.35e-2)" "unprognostic (1.52e-2)" "unprognostic (4.62e-2)" "unprognostic (5.63e-2)" "prognostic favorable (6.16e-6)" "unprognostic (1.34e-1)" "prognostic unfavorable (1.09e-6)" "unprognostic (5.71e-2)" "unprognostic (1.53e-1)" "unprognostic (9.51e-2)" "prognostic favorable (2.85e-5)" 11.1 8.2 7.0 3.7 7.4 2.7 8.7 6.6 8.0 7.2 5.1 7.6 4.9 5.6 5.9 5.0 6.9 6.1 5.3 5.9 6.4 6.0 8.8 4.9 5.4 6.9 6.8 6.5 6.0 8.9 6.6 6.1 6.2 8.4 4.9 3.1 6.2 7.0 12.1 5.1 5.6 6.7 6.4 6.6 7.1 2.7 6.7 5.4 6.3 10.2 5.0 7.3 6.3 7.0 4.9 6.0 6.7 10.0 20.9 9.2 4.0 8.6 6.7 12.6 11.7 5.0 2.4 3.7 6.7 7.2 15.9 5.1 9.7 11.9 11.4 13.0 6.7 6.5 3.4 3.7 10.9 4.9 8.2 9.6 10.6 12.1 13.6 10.6 9.1 7.4 6.6 4.2 11.9 3.9 7.2 2.9 3.3 9.8 6.4 5.2 13.9 3.5 5.8 3.0 6.3 3.3 5.3 7.3 7.9 7.6 4.0 3.5 4.8 9.1 4.9 7.9 8.0 5.0 9.9 4.9 9.1 5.7 9.4 6.5 2.7 8.0 5.0 1.9 2.7 3.1 3.2 2.0 3.2 2.6 2.7 4.8 2.5 5.0 4.5 0.9 5.5 2.8 7.0 7.4 6.6 8.0 5.9 6.4 6.9 6.8 6.2 6.4 6.7 7.0 9.0 6.4 8.4 36.9 15.7 4.7 10.0 13.0 8.6 27.2 10.7 7.6 5.2 10.0 16.7 11.0 29.2 15.2 9.8 17.3 7.9 8.6 5.6 4.6 6.9 9.5 8.4 7.4 24.3 9.1 5.9 10.0 12.8 4.0 8.9 20.7 12.5 7.5 8.6 30.3 21.4 11.4 14.2 10.0 9.3 5.6 19.3 9.5 17.8 18.7 16.5 14.1 28.8 28.6 49.7 10.4 15.3 23.7 7.7 10.8 24.9 7.1 11.7 30.9 19.7 10.0 8.0 19.7 10.9 6.7 6.5 12.4 14.0 18.3 12.7 9.4 CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 548.8;Hofbauer cells: 1107.4;Macrophages: 432.1;monocytes: 432.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1136.5;classical monocyte: 1139.3;eosinophil: 712.7;intermediate monocyte: 431.6;memory B-cell: 575.6;myeloid DC: 1363.2;naive B-cell: 516.8;NK-cell: 605.5;plasmacytoid DC: 959.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 563.6;HMC-1: 972.7;SK-MEL-30: 722.2;THP-1: 513.5;U-937: 569.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Enhanced Nucleoplasm Yes No 5400000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "HPA018843: AB_2669948, HPA019080: AB_1845979, HPA019092: AB_1845980" "unprognostic (2.82e-2)" "unprognostic (1.37e-1)" "unprognostic (8.80e-2)" "unprognostic (1.28e-2)" "unprognostic (4.37e-2)" "unprognostic (7.52e-2)" "prognostic unfavorable (3.22e-5)" "unprognostic (8.83e-2)" "unprognostic (3.22e-2)" "unprognostic (1.54e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-1)" "prognostic favorable (2.96e-4)" "unprognostic (1.45e-1)" "unprognostic (7.68e-2)" "unprognostic (5.30e-3)" "unprognostic (7.89e-3)" 92.4 26.3 42.8 82.4 44.2 159.3 94.9 46.3 79.6 119.1 37.5 56.9 30.3 50.0 46.2 289.5 48.7 44.4 19.2 41.7 51.1 201.1 8.9 175.7 117.9 60.2 46.3 19.7 44.9 151.7 27.2 26.1 57.2 76.5 42.9 4.2 111.8 38.0 16.5 219.9 54.2 24.5 57.5 46.2 94.4 26.0 66.1 58.0 162.3 5.8 109.5 97.1 174.8 79.4 165.5 75.9 0.7 6.9 50.2 102.8 83.7 59.6 6.1 51.2 49.8 9.4 563.6 28.1 96.6 116.0 64.0 181.1 0.2 113.7 23.0 142.0 4.4 74.3 128.0 29.3 40.6 44.8 972.7 93.8 80.5 53.8 70.3 3.6 37.5 143.8 8.2 60.1 38.1 150.1 101.3 414.8 23.2 166.5 112.8 87.3 13.3 11.8 220.6 77.7 0.8 1.4 86.9 128.4 722.2 44.2 40.0 513.5 148.7 111.6 26.8 4.6 2.4 1.4 6.2 10.3 259.5 569.5 1.5 1136.5 1139.3 712.7 12.2 431.6 39.2 575.6 107.8 41.1 1363.2 516.8 30.5 13.9 162.9 605.5 131.3 959.7 122.1 977.9 42.8 44.2 46.3 79.6 41.7 51.1 60.2 46.3 57.2 57.5 66.1 79.4 6.6 19.2 24.5 3.3 84.7 121.2 167.5 265.0 60.9 0.8 86.8 70.4 1.3 51.5 119.6 316.3 0.0 34.3 91.5 211.0 211.3 113.8 4.1 33.0 10.3 16.2 28.8 16.0 0.2 91.5 324.0 34.7 124.9 63.9 548.8 1.2 3.6 1.1 1107.4 1.7 0.2 55.9 50.8 141.6 337.2 15.2 46.9 432.1 147.7 1.0 432.4 43.6 11.3 0.5 0.1 405.8 205.4 22.6 17.2 106.0 74.1 168.5 48.8 1.7 13.1 2.0 54.0 9.6 33.1 167.4 169.5 35.7 101.9 0.9 83.9 253.1 SH2D6 FLJ35993 ENSG00000152292 "SH2 domain containing 6" 2 85418931-85437029 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "intestine: 1.9" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 10.7;Gastric mucus-secreting cells: 18.3;Proximal tubular cells: 16.7;Spermatocytes: 6.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "LHCN-M2: 1.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA053873 Uncertain NA NA "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA053873: AB_2682286" "unprognostic (4.70e-1)" "unprognostic (3.55e-2)" "unprognostic (3.30e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.67e-2)" "unprognostic (7.95e-3)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (1.46e-1)" "unprognostic (2.70e-1)" "unprognostic (2.49e-1)" "unprognostic (5.06e-7)" "unprognostic (2.54e-1)" "unprognostic (8.65e-2)" "unprognostic (1.23e-2)" "unprognostic (5.65e-3)" 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.8 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.4 0.1 0.2 0.3 0.2 0.3 0.1 0.3 0.4 0.0 0.0 0.0 1.3 0.2 0.0 0.5 0.0 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 1.9 0.0 0.3 0.1 0.1 0.0 10.7 0.0 0.6 0.0 0.0 0.1 18.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 2.0 0.0 0.3 0.3 0.4 0.0 0.2 0.0 0.0 0.0 0.4 0.0 1.0 2.4 0.1 2.3 0.4 0.1 0.3 0.6 16.7 0.0 0.2 0.0 0.8 0.2 6.8 2.3 0.0 0.0 0.1 0.3 0.1 1.5 0.0 MAT2A "MATA2, MATII, SAMS2" ENSG00000168906 "Methionine adenosyltransferase 2A" P31153 2 85539168-85545281 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 874.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009968, HPA043028" Approved Approved Nucleoplasm,Cytosol NA NA 1800000 "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "CAB009968: AB_675710, HPA043028: AB_10960707" "unprognostic (1.38e-3)" "unprognostic (2.58e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (5.29e-5)" "unprognostic (9.89e-3)" "unprognostic (5.90e-3)" "prognostic unfavorable (4.87e-4)" "prognostic favorable (8.94e-4)" "prognostic unfavorable (5.94e-5)" "unprognostic (4.07e-2)" "unprognostic (2.02e-1)" "unprognostic (2.59e-2)" "unprognostic (9.63e-3)" "unprognostic (1.04e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (1.77e-2)" 270.4 277.5 184.1 153.2 226.7 98.3 136.1 199.3 235.9 173.0 152.6 193.2 141.4 165.5 236.0 166.2 200.1 209.5 189.6 191.5 207.3 203.6 115.7 168.5 121.8 226.8 219.3 211.0 874.7 165.8 284.1 122.3 208.0 196.2 146.5 248.7 137.7 120.0 278.9 141.1 155.6 127.2 194.4 116.7 225.5 132.3 219.2 102.1 388.8 112.0 127.7 262.9 168.2 289.7 175.3 253.0 290.4 181.6 195.3 236.7 171.1 213.5 195.6 219.3 232.4 208.4 569.9 404.5 137.0 261.0 178.9 264.3 369.6 318.6 279.8 207.0 271.0 242.5 408.7 181.9 355.6 364.3 259.7 215.9 315.8 237.4 164.1 278.1 211.5 230.7 277.9 309.0 505.1 149.5 334.4 398.2 193.5 148.7 320.8 350.3 275.0 264.2 328.9 271.2 227.9 209.6 193.2 183.4 354.6 145.9 156.0 192.3 207.7 267.4 160.9 149.3 260.5 189.0 161.4 290.6 175.0 447.3 143.8 9.1 24.7 8.2 22.3 26.9 32.7 19.8 25.2 23.7 23.6 18.9 23.1 20.5 2.5 27.3 22.3 16.6 24.2 24.9 184.1 226.7 199.3 235.9 191.5 207.3 226.8 219.3 208.0 194.4 219.2 289.7 150.5 48.1 83.6 122.4 104.2 143.5 217.1 47.1 206.1 73.5 116.3 134.6 6.5 82.9 57.6 71.7 68.8 36.2 126.3 60.6 19.6 59.2 75.2 28.8 49.2 83.6 83.3 87.1 56.1 58.5 40.6 121.9 106.0 47.4 84.4 83.3 45.0 44.6 67.4 26.9 60.4 65.1 26.4 118.8 141.9 25.8 72.1 165.7 67.6 26.2 64.6 58.8 27.8 28.6 95.5 53.6 48.0 83.8 78.4 66.7 73.8 138.7 35.2 89.0 111.7 298.5 231.0 54.1 56.2 168.2 118.3 38.2 102.0 51.1 70.6 88.4 GGCX VKCFD1 ENSG00000115486 "Gamma-glutamyl carboxylase" P38435 2 85544720-85561547 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 118.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 163.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018284 Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "HPA018284: AB_1849641" "unprognostic (4.88e-3)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (1.82e-6)" "unprognostic (5.67e-2)" "unprognostic (1.85e-3)" "unprognostic (2.96e-2)" "unprognostic (3.77e-2)" "unprognostic (5.64e-2)" "unprognostic (2.18e-2)" "unprognostic (6.45e-3)" "unprognostic (5.23e-2)" "unprognostic (8.17e-3)" "unprognostic (7.85e-2)" "unprognostic (2.59e-1)" "unprognostic (7.63e-3)" "unprognostic (9.38e-2)" 13.8 11.0 6.0 8.3 7.4 3.2 10.8 8.3 7.7 10.7 11.7 7.8 7.4 10.5 13.8 9.2 10.5 11.3 9.5 6.9 6.2 16.3 118.8 13.8 6.3 7.4 6.9 12.4 15.8 18.0 7.8 23.4 7.5 10.0 9.9 7.7 14.7 12.1 7.9 9.2 7.3 13.4 7.3 6.2 9.1 4.7 7.0 4.8 12.6 8.6 7.2 12.2 8.8 11.2 17.1 27.2 19.0 21.3 93.8 26.6 42.2 29.9 35.1 21.6 30.4 47.3 20.6 6.1 29.7 49.3 27.1 27.2 13.7 37.7 23.7 10.9 18.7 11.1 17.4 45.2 34.8 7.0 10.1 33.1 22.0 43.8 29.7 35.6 31.0 10.8 13.5 8.7 63.5 22.4 3.5 5.3 8.9 47.7 23.4 6.6 44.6 15.3 30.0 32.5 7.2 12.1 26.8 52.2 28.2 32.1 25.6 6.8 28.6 27.5 23.9 27.1 20.9 6.8 20.1 5.1 26.5 7.1 39.4 3.7 4.2 2.2 1.7 4.4 1.6 0.4 0.7 0.7 2.9 0.4 1.7 1.6 1.7 1.4 2.6 2.4 1.2 2.0 6.0 7.4 8.3 7.7 6.9 6.2 7.4 6.9 7.5 7.3 7.0 11.2 27.1 28.9 40.3 10.1 25.1 18.7 20.6 27.8 13.6 21.6 22.9 19.8 27.9 32.9 24.1 29.5 16.7 60.8 28.4 16.1 7.9 29.9 4.2 16.9 19.4 20.8 14.4 5.7 10.9 39.5 50.2 29.4 11.7 26.8 15.8 17.8 23.9 163.0 31.3 8.4 8.9 17.6 22.4 26.9 29.0 2.2 20.2 24.5 21.4 5.6 29.6 19.5 17.5 9.5 12.6 25.0 12.6 20.3 38.4 16.4 16.2 27.1 16.9 33.6 6.6 42.3 22.8 23.5 11.2 20.0 15.2 53.8 20.8 15.1 16.4 23.6 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 RNF181 HSPC238 ENSG00000168894 "Ring finger protein 181" Q9P0P0 2 85595725-85597708 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 851.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046112, HPA062121" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA046112: AB_2679542, HPA062121: AB_2684687" "unprognostic (3.79e-1)" "unprognostic (8.31e-2)" "unprognostic (5.08e-2)" "unprognostic (2.05e-1)" "unprognostic (3.24e-1)" "unprognostic (1.67e-2)" "unprognostic (3.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.22e-2)" "unprognostic (5.85e-2)" "unprognostic (1.11e-1)" "unprognostic (4.96e-2)" "prognostic unfavorable (1.06e-6)" "unprognostic (3.24e-1)" "unprognostic (2.04e-1)" "prognostic favorable (4.59e-5)" "unprognostic (1.49e-2)" 110.4 135.0 87.6 60.2 92.4 76.7 109.8 93.3 101.9 105.5 85.7 101.3 75.1 85.2 85.0 118.0 87.4 50.2 141.1 88.9 93.2 174.3 169.5 114.0 69.1 92.8 91.5 90.7 168.5 80.1 61.9 82.9 91.8 111.0 69.0 36.0 110.0 73.0 172.1 102.6 91.4 65.2 93.7 101.2 121.8 107.6 94.5 59.5 93.8 105.1 89.6 107.5 98.7 97.7 125.7 120.4 96.3 103.8 94.3 113.4 152.2 104.7 195.4 207.7 199.7 185.2 132.2 118.8 196.8 150.6 206.2 117.5 83.5 164.8 223.8 133.9 104.0 91.6 58.5 224.7 168.0 104.8 122.1 122.0 208.5 144.5 237.1 166.2 175.4 110.8 109.1 119.7 282.7 193.0 97.8 235.6 68.6 164.9 180.2 105.1 202.5 171.7 200.8 109.3 57.2 74.5 88.4 126.2 171.7 114.8 125.4 136.2 160.1 104.9 77.2 218.4 149.6 170.3 143.5 143.1 166.4 144.9 95.5 213.9 418.5 339.7 176.1 326.0 164.6 251.9 181.4 169.2 321.4 214.8 156.4 153.0 356.6 195.5 254.9 360.4 262.0 439.0 87.6 92.4 93.3 101.9 88.9 93.2 92.8 91.5 91.8 93.7 94.5 97.7 89.3 147.4 104.8 7.8 89.3 116.9 102.5 343.7 75.7 27.1 92.8 95.4 122.8 124.4 200.2 150.8 2.1 237.1 104.2 148.1 416.7 236.5 365.7 70.5 63.6 102.8 70.2 85.2 2.2 290.4 260.2 113.7 55.0 93.2 102.7 59.0 99.6 214.4 263.4 18.5 2.2 138.4 185.1 154.0 182.3 250.6 88.3 147.6 170.7 3.7 188.7 80.4 94.7 2.0 6.9 304.0 201.5 78.2 113.8 123.8 271.9 851.7 141.7 29.1 59.2 66.3 108.8 121.3 33.1 97.9 118.6 221.2 86.7 62.6 102.0 115.6 TMEM150A "FLJ90024, TM6P1, TMEM150, TTN1" ENSG00000168890 "Transmembrane protein 150A" Q86TG1 2 85598547-85603196 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 133.5;Early spermatids: 137.5;Proximal tubular cells: 85.0;Syncytiotrophoblasts: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 52.9;HHSteC: 49.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019015 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA019015: AB_2204758" "unprognostic (2.80e-1)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-3)" "unprognostic (4.09e-3)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (1.42e-2)" "unprognostic (5.80e-2)" "unprognostic (2.64e-2)" "unprognostic (2.54e-3)" "unprognostic (7.16e-2)" "unprognostic (8.27e-3)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (1.37e-2)" "unprognostic (6.87e-3)" 18.7 16.3 10.0 5.2 10.8 1.2 17.0 9.8 11.1 16.3 11.1 21.0 6.5 17.7 6.3 11.0 17.1 10.4 15.5 9.7 10.3 32.8 38.5 19.3 6.0 11.9 10.7 17.1 37.9 8.0 11.7 22.4 10.9 17.4 4.1 1.4 14.9 10.2 53.7 9.3 12.9 11.5 10.6 9.7 20.6 24.4 11.3 2.5 14.9 27.2 4.2 22.2 13.1 10.1 2.7 5.1 6.3 9.3 52.9 23.7 15.3 5.2 9.1 4.3 2.0 23.6 7.1 0.8 19.8 15.3 8.0 2.2 6.8 13.7 2.0 1.2 6.7 1.5 3.0 39.9 49.6 0.4 4.7 28.5 18.4 7.0 9.9 20.6 15.2 1.0 14.0 1.5 17.5 11.9 0.4 6.9 11.5 10.8 5.1 4.1 0.6 15.8 13.4 10.6 1.0 3.9 5.4 35.4 13.5 5.9 8.7 6.2 12.6 5.2 4.4 4.5 1.8 10.6 2.8 5.2 8.5 6.0 2.3 0.0 15.2 7.2 5.5 17.9 6.5 5.3 6.2 5.6 12.8 8.1 6.9 4.2 0.7 8.4 15.1 7.6 1.5 6.0 10.0 10.8 9.8 11.1 9.7 10.3 11.9 10.7 10.9 10.6 11.3 10.1 24.1 9.6 14.9 10.7 9.0 4.5 15.3 16.0 10.2 6.8 15.3 12.7 5.2 12.8 16.2 14.7 0.0 133.5 10.4 3.5 29.4 16.9 137.5 5.0 9.0 14.9 3.0 1.7 3.9 14.4 18.2 14.3 5.6 6.0 10.2 5.2 15.7 19.7 37.9 3.3 5.0 5.2 16.2 10.3 13.1 64.8 19.9 14.6 10.6 9.4 15.2 6.5 7.2 5.5 5.9 12.8 7.0 24.5 5.9 20.3 16.4 85.0 8.3 3.4 13.1 14.6 11.7 2.4 5.6 7.9 3.7 146.0 7.0 9.2 7.0 13.1 USP39 "CGI-21, SAD1, SNRNP65" ENSG00000168883 "Ubiquitin specific peptidase 39" Q53GS9 2 85602856-85649283 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034823, HPA077350" Supported Supported Supported Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA034823: AB_10602488, HPA077350: " "unprognostic (1.10e-2)" "unprognostic (3.31e-3)" "unprognostic (1.83e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (8.46e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (2.84e-6)" "unprognostic (1.10e-2)" "unprognostic (1.69e-1)" "unprognostic (1.89e-1)" "unprognostic (5.17e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (4.05e-7)" "unprognostic (3.95e-3)" "unprognostic (2.25e-1)" "unprognostic (2.52e-2)" "unprognostic (2.52e-1)" 22.6 16.1 18.1 19.8 18.7 40.8 21.3 19.0 20.6 22.2 22.7 24.2 17.1 23.5 26.1 22.7 19.5 12.7 22.7 17.9 19.5 21.7 18.5 21.4 26.5 18.9 18.4 20.1 17.2 21.8 14.3 26.9 18.9 18.7 22.7 22.0 19.0 21.2 55.2 23.8 19.5 21.3 18.9 20.9 20.6 15.6 18.8 41.0 19.8 42.6 32.2 24.7 20.6 19.8 71.0 70.0 70.0 77.5 49.7 38.7 79.5 59.2 54.6 84.1 74.5 113.9 49.8 83.0 53.4 54.6 62.3 50.6 135.7 62.5 105.8 83.9 86.4 103.4 39.1 100.6 49.0 127.4 67.5 27.9 49.3 65.1 57.8 39.3 68.1 85.3 129.8 47.2 62.8 81.4 125.2 94.8 92.8 84.9 64.2 114.1 150.0 63.1 45.0 53.8 65.1 53.7 36.4 58.9 51.4 56.7 39.5 60.5 43.9 51.7 65.0 62.7 97.2 42.0 83.0 87.7 44.9 130.5 63.6 51.1 35.8 44.5 40.2 42.4 46.6 34.7 41.8 41.7 40.6 37.0 40.4 37.0 23.1 40.4 41.6 32.0 53.4 43.6 18.1 18.7 19.0 20.6 17.9 19.5 18.9 18.4 18.9 18.9 18.8 19.8 18.4 19.2 25.2 19.9 17.5 20.5 16.7 17.9 22.2 8.5 14.1 14.0 17.3 11.5 19.9 12.9 8.4 54.1 17.8 14.8 21.5 21.1 26.1 9.8 15.4 17.1 12.1 18.3 13.9 18.8 31.8 17.1 9.7 11.7 17.1 16.3 17.5 14.2 25.6 5.0 18.2 13.4 24.4 11.9 14.7 13.0 19.3 17.6 19.6 17.8 26.4 15.3 12.3 16.1 33.1 19.2 8.5 18.8 14.0 16.0 11.2 14.6 15.6 11.6 0.0 13.0 17.7 19.5 17.1 15.5 16.2 35.7 21.3 12.7 15.7 16.3 C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: AB_2681360" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.12e-6)" "unprognostic (9.34e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.76e-6)" "unprognostic (4.24e-3)" "unprognostic (8.41e-2)" "unprognostic (2.34e-1)" "unprognostic (2.88e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (1.18e-1)" "unprognostic (1.76e-1)" "unprognostic (3.70e-2)" "unprognostic (8.81e-3)" 11.0 9.4 8.8 10.0 11.6 10.5 12.6 15.4 9.9 18.7 10.7 13.6 11.0 15.7 12.2 12.1 15.2 6.6 12.3 8.6 9.4 12.8 11.7 14.0 14.2 11.7 10.8 20.4 17.2 8.5 14.0 12.5 11.0 16.4 10.9 20.0 16.4 10.7 21.8 16.3 16.6 9.9 9.8 16.9 14.3 9.5 10.2 13.7 16.3 9.8 13.9 13.6 15.4 15.2 8.8 7.9 15.7 11.5 14.2 7.6 10.2 4.3 5.6 6.7 8.7 7.1 10.6 12.4 6.0 7.3 6.0 10.4 7.9 7.5 7.2 6.8 19.1 21.1 13.8 8.5 11.2 12.3 11.4 11.3 9.7 4.4 12.7 10.6 10.1 14.7 10.7 12.4 6.3 9.3 13.3 13.4 6.9 10.2 7.3 14.8 27.8 11.5 8.5 10.1 19.8 14.2 6.5 8.5 9.0 8.7 9.1 6.5 7.0 4.8 12.8 5.9 4.2 17.9 11.8 10.8 7.2 12.9 6.0 32.7 30.5 59.0 22.4 21.8 21.3 14.6 21.1 21.0 22.4 20.7 30.5 28.2 49.2 31.2 27.0 15.2 17.7 16.7 8.8 11.6 15.4 9.9 8.6 9.4 11.7 10.8 11.0 9.8 10.2 15.2 8.2 64.1 63.1 15.0 18.6 5.9 18.2 10.0 9.6 17.4 16.0 12.3 10.7 37.1 24.3 35.0 35.5 47.2 24.4 24.6 17.6 17.9 4.8 9.4 8.7 13.9 19.2 19.5 2.7 19.8 17.7 12.9 17.9 9.6 34.7 15.6 17.9 25.3 23.3 25.2 6.8 16.9 12.2 34.9 14.3 12.8 24.2 26.0 14.2 15.0 31.4 12.3 38.1 10.1 16.9 19.4 14.0 13.5 13.6 14.4 32.7 26.6 21.0 27.0 19.7 13.7 8.5 37.2 20.1 27.4 9.8 24.9 18.1 10.0 15.8 19.2 SFTPB "SFTP3, SP-B" ENSG00000168878 "Surfactant protein B" P07988 2 85657314-85668741 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 32 "lung: 3566.0" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 15343.4" "Cancer enriched" "Detected in many" 5 "lung cancer: 1306.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 2.8;NB-4: 3.5;U-2197: 6.7;U-266/70: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002440, HPA034820, HPA062148" Enhanced "Secreted in other tissues" NA NA 80000000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "CAB002440: AB_564142, HPA034820: AB_2674347, HPA062148: AB_2684697" "unprognostic (6.46e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.71e-6)" "unprognostic (2.25e-3)" "unprognostic (4.57e-3)" "unprognostic (8.57e-3)" "unprognostic (6.45e-3)" "unprognostic (1.13e-1)" "unprognostic (3.04e-2)" "unprognostic (2.50e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (2.99e-6)" "unprognostic (2.37e-1)" "unprognostic (1.09e-1)" "unprognostic (7.90e-2)" "unprognostic (4.38e-2)" 0.8 4.4 1.5 2.2 1.4 0.4 0.5 1.7 3.0 0.5 1.1 0.5 0.3 0.2 0.7 0.4 0.3 0.2 1.4 1.3 2.1 2.1 1.2 3566.0 0.3 1.4 1.1 11.0 0.9 0.2 5.4 1.5 1.5 1.2 0.4 2.9 0.5 2.0 1.2 0.8 0.7 0.1 0.8 4.1 5.1 0.4 1.4 0.3 113.1 0.3 0.2 0.2 0.4 1.5 0.1 0.2 0.2 0.5 0.3 0.5 2.8 0.2 0.2 0.1 0.0 0.3 0.6 0.0 0.2 0.0 0.3 2.0 0.2 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.1 0.1 1.4 0.0 0.3 0.2 0.1 0.5 0.0 0.4 0.3 0.4 0.1 0.3 1.1 3.5 1.6 0.5 0.4 1.3 0.2 0.3 0.2 0.3 0.4 0.3 0.0 0.4 0.2 0.3 0.3 0.3 0.0 0.2 0.6 6.7 0.1 2.4 0.6 0.2 0.6 0.5 0.1 0.3 0.6 0.2 0.2 1.1 0.1 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 0.2 0.7 0.2 0.4 0.4 1.5 1.4 1.7 3.0 1.3 2.1 1.4 1.1 1.5 0.8 1.4 1.5 0.0 3650.6 15343.4 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.5 0.0 1930.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 14.4 0.0 0.0 0.2 0.2 0.0 26.9 0.0 0.0 262.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 16.2 0.0 0.3 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 185.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 36.5 0.0 0.0 0.2 GNLY "D2S69E, LAG-2, LAG2, NKG5, TLA519" ENSG00000115523 Granulysin P22749 2 85685175-85698852 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 288.7;endometrium 1: 71.9;lymphoid tissue: 86.3" "Group enriched" "Detected in many" 5 "dendritic cells: 5070.6;NK-cells: 8318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "NK-cell: 17623.2" "Group enriched" "Detected in all" 63 "NK-cells: 17623.2;T-cells: 7874.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025186, HPA058021" Enhanced "Secreted to blood" NA NA 2920000 17000 "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025186: , HPA058021: AB_2683581" "unprognostic (5.80e-2)" "unprognostic (5.64e-3)" "unprognostic (6.68e-2)" "prognostic favorable (3.48e-5)" "unprognostic (4.34e-2)" "unprognostic (9.22e-2)" "unprognostic (2.60e-1)" "unprognostic (2.79e-2)" "prognostic favorable (6.60e-5)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (8.46e-2)" "unprognostic (3.37e-1)" "unprognostic (1.86e-1)" "prognostic favorable (8.07e-4)" 6.9 2.7 8.1 11.6 7.8 288.7 5.2 8.1 18.7 4.3 7.1 5.7 4.0 71.9 3.9 2.6 6.1 6.5 4.3 7.8 9.8 2.9 10.4 36.8 21.9 12.7 11.6 1.5 1.2 0.8 1.8 17.0 10.6 2.0 6.1 0.5 2.0 5.3 9.2 1.5 10.3 4.3 8.8 86.3 5.0 0.9 9.8 3.5 3.6 3.5 17.6 6.4 2.5 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.0 177.1 26.2 17.7 7874.6 26.3 2145.8 34.2 837.4 3344.7 22.4 23.0 231.3 2928.7 202.5 17623.2 32.3 58.2 40.3 8118.6 8.1 7.8 8.1 18.7 7.8 9.8 12.7 11.6 10.6 8.8 9.8 9.8 26.8 12.8 78.9 0.0 23.3 7.0 0.2 0.0 0.0 0.1 7.2 3.7 3.0 10.0 6.2 0.0 2.1 2.3 5070.6 1.3 1.9 1.9 0.0 7.5 12.0 13.0 1.8 47.2 0.2 0.0 3.4 29.3 0.5 10.6 52.4 0.1 23.2 5.3 6.0 0.0 0.1 3.3 0.0 22.4 7.2 0.2 0.3 28.4 80.0 9.4 48.6 0.1 8318.3 0.0 0.1 0.0 1.2 0.0 247.4 0.1 2.4 9.5 3.6 0.2 0.0 7.0 5.4 0.2 0.6 0.6 7.7 1.1 1230.0 1.0 1.6 0.6 ATOH8 "bHLHa21, FLJ14708, HATH6" ENSG00000168874 "Atonal bHLH transcription factor 8" Q96SQ7 2 85751344-85791383 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 54.7" "Cell type enhanced" "Detected in many" "Adipocytes: 123.8;Endothelial cells: 41.7;Hepatocytes: 39.1;Muller glia cells: 32.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 6.2;fHDF/TERT166: 6.8;hTERT-RPE1: 5.0;RH-30: 9.5;RT4: 5.6;TIME: 7.9;U-2197: 5.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA028406 Supported Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "HPA028406: AB_2672587" "unprognostic (7.70e-2)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (2.84e-3)" "unprognostic (2.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.78e-1)" "unprognostic (6.28e-3)" "unprognostic (1.56e-1)" "prognostic favorable (8.98e-6)" "unprognostic (3.32e-2)" "prognostic favorable (3.80e-5)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.96e-1)" "unprognostic (1.91e-2)" 33.8 1.8 2.1 0.3 2.2 0.0 29.9 2.7 1.6 20.9 0.5 8.8 0.2 25.9 0.2 5.6 19.4 0.4 30.6 1.5 5.1 7.3 25.1 25.6 0.8 5.7 4.9 15.0 4.2 0.2 5.4 0.3 5.3 17.4 0.4 0.6 5.2 1.9 54.7 19.9 8.9 1.3 1.6 12.2 9.4 2.1 3.1 0.2 48.5 2.0 0.1 21.7 20.6 3.3 0.0 1.1 4.1 6.2 3.0 0.4 0.0 3.4 0.5 0.8 0.3 0.0 0.0 0.0 1.1 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.1 1.6 0.0 0.0 2.1 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 9.5 0.0 0.0 5.6 3.0 1.4 0.6 0.0 0.6 0.0 0.0 0.0 7.9 1.2 0.0 5.5 0.0 0.0 0.0 0.0 0.8 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.2 2.7 1.6 1.5 5.1 5.7 4.9 5.3 1.6 3.1 3.3 123.8 9.6 18.3 10.7 0.3 2.5 8.5 11.8 0.6 0.4 0.5 0.8 13.2 5.7 17.5 1.8 0.0 0.1 0.1 1.1 0.0 11.9 13.6 5.9 5.7 41.7 4.2 0.0 0.3 2.3 0.6 11.4 1.1 20.5 1.3 5.3 5.7 39.1 3.2 0.0 0.3 2.2 6.1 3.1 4.0 25.9 3.4 4.3 1.8 5.6 0.6 32.3 0.0 14.6 3.1 1.0 5.5 0.4 0.0 4.5 0.0 0.6 2.4 1.3 0.0 12.2 11.6 3.0 2.7 0.2 1.4 0.3 0.5 0.1 1.0 2.3 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 POLR1A "DKFZP586M0122, FLJ21915, RPA1, RPA190, RPO1-4" ENSG00000068654 "RNA polymerase I subunit A" O95602 2 86020216-86106155 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010145, HPA031513, HPA049700" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center,Intermediate filaments" No No "Cluster 7: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" "Nucleoplasm, Intermediate filaments" "CAB010145: AB_675814, HPA031513: AB_2673916, HPA049700: AB_2680856" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (3.70e-9)" "unprognostic (1.06e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.31e-2)" "unprognostic (4.56e-2)" "unprognostic (3.27e-1)" "unprognostic (2.20e-3)" "unprognostic (1.94e-1)" "prognostic unfavorable (8.41e-4)" "unprognostic (7.20e-2)" 5.4 5.7 3.7 5.8 4.0 4.9 4.5 3.1 4.7 4.9 4.0 4.9 4.1 8.2 3.0 6.0 5.2 2.9 5.8 3.9 3.6 4.6 5.0 4.0 4.6 3.4 3.6 5.2 5.2 7.1 4.9 5.0 3.3 4.5 5.0 3.5 3.9 5.1 10.8 5.5 3.8 6.9 2.7 3.8 4.5 6.2 4.4 6.2 4.5 7.4 4.9 5.2 4.2 4.3 18.5 41.1 18.0 34.7 17.2 13.7 25.9 16.6 10.9 23.2 14.4 51.9 14.2 41.9 17.2 17.0 22.7 20.9 46.6 24.4 20.6 17.6 24.0 36.2 18.0 35.1 12.1 34.8 18.7 10.5 15.0 34.6 26.7 8.8 18.2 19.0 48.8 10.3 16.2 16.4 25.8 15.1 32.7 24.4 26.8 30.7 39.5 19.6 10.5 29.7 27.7 14.6 18.3 23.8 12.7 12.3 14.0 12.0 29.3 28.0 22.2 24.3 33.8 14.5 15.3 35.7 14.6 29.3 25.3 0.5 0.4 0.0 0.7 0.6 0.9 0.5 0.3 0.6 0.4 0.6 0.3 0.4 0.1 0.5 0.5 0.7 0.1 0.4 3.7 4.0 3.1 4.7 3.9 3.6 3.4 3.6 3.3 2.7 4.4 4.3 4.9 3.2 9.1 13.4 8.8 4.2 4.9 5.3 12.0 12.4 6.2 5.5 11.1 8.6 4.7 9.2 16.7 6.3 7.2 5.1 3.9 6.0 3.0 5.4 13.8 6.5 9.6 10.9 19.7 4.9 5.4 7.7 8.2 6.9 6.3 11.0 4.2 8.3 12.5 11.8 18.1 6.7 2.0 3.1 3.5 1.7 6.2 5.5 5.4 6.5 3.3 4.2 6.2 20.1 18.2 6.6 3.0 5.3 10.1 9.1 3.5 3.4 5.2 9.7 0.0 14.3 6.2 5.0 7.2 13.4 2.7 3.8 7.5 12.4 10.4 4.0 PTCD3 "DKFZp666K071, FLJ20758" ENSG00000132300 "Pentatricopeptide repeat domain 3" Q96EY7 2 86106223-86142157 "Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041154, HPA041382" Supported Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA041154: AB_10795488, HPA041382: AB_10795695" "unprognostic (1.16e-2)" "unprognostic (4.47e-2)" "unprognostic (1.37e-2)" "unprognostic (9.30e-3)" "unprognostic (2.40e-2)" "unprognostic (2.54e-1)" "unprognostic (4.92e-3)" "unprognostic (2.06e-2)" "unprognostic (4.78e-2)" "unprognostic (3.78e-1)" "unprognostic (7.42e-3)" "unprognostic (5.49e-3)" "unprognostic (1.26e-1)" "prognostic favorable (6.77e-4)" "unprognostic (3.69e-1)" "unprognostic (7.79e-2)" "prognostic favorable (6.86e-4)" 10.0 15.8 13.1 7.6 14.2 14.7 9.9 15.2 15.9 11.6 16.3 12.6 10.1 11.7 10.2 10.7 11.7 6.4 26.2 13.3 14.5 12.4 16.5 9.6 11.8 13.6 14.0 15.1 10.7 13.1 14.8 9.2 14.7 10.4 13.5 13.2 9.8 7.5 32.8 10.3 11.9 9.0 13.7 12.0 11.8 16.6 13.5 10.5 12.0 36.3 11.1 10.3 10.7 16.7 16.2 37.6 22.0 18.5 16.1 16.6 26.2 32.6 13.8 18.0 18.0 69.9 15.1 39.7 11.8 17.1 18.6 28.9 44.7 17.7 22.9 17.8 37.0 31.8 23.0 59.2 16.3 26.0 23.1 19.8 12.8 13.7 24.4 18.8 15.7 28.6 33.5 14.8 16.0 15.0 21.7 31.0 20.2 31.5 23.9 28.8 30.9 30.6 24.6 31.7 23.9 14.7 15.2 25.0 30.4 20.6 13.2 15.7 11.3 14.2 15.1 14.6 19.2 33.7 47.6 31.6 13.8 29.4 11.1 4.4 9.6 7.6 12.4 7.0 14.6 15.3 11.2 13.2 10.6 16.4 15.1 11.3 0.3 14.3 14.1 10.7 13.9 8.8 13.1 14.2 15.2 15.9 13.3 14.5 13.6 14.0 14.7 13.7 13.5 16.7 17.1 57.7 33.5 50.3 31.0 26.0 26.3 27.7 34.7 61.7 19.2 16.8 105.7 18.6 37.4 23.9 66.7 53.0 30.6 21.7 25.4 18.8 34.8 27.5 33.3 23.5 31.1 39.5 52.9 11.9 27.0 30.5 30.1 24.2 33.6 47.5 21.4 41.7 21.7 37.0 53.1 25.3 20.3 19.6 13.3 22.4 27.1 17.7 8.8 21.5 22.7 49.8 28.8 48.7 53.4 15.0 19.2 19.5 26.4 23.7 23.2 30.1 26.2 65.3 13.1 36.3 21.3 98.3 62.4 28.7 24.7 36.7 31.8 47.9 38.5 20.4 IMMT "HMP, Mic60, MICOS60, MINOS2, P87, P89" ENSG00000132305 "Inner membrane mitochondrial protein" Q16891 2 86143932-86195472 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 288.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022439, HPA036164, HPA036165" Supported Enhanced Mitochondria NA NA 220000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB022439: , HPA036164: AB_2674979, HPA036165: AB_2674980" "unprognostic (3.83e-3)" "unprognostic (1.56e-1)" "unprognostic (1.95e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (1.40e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (5.66e-2)" "unprognostic (1.53e-1)" "unprognostic (8.10e-2)" "unprognostic (7.35e-2)" "unprognostic (2.21e-1)" "prognostic favorable (3.51e-6)" "unprognostic (2.06e-3)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" 41.3 82.4 30.3 34.9 31.8 40.3 36.5 33.1 39.0 30.2 41.9 57.4 57.4 35.0 27.6 43.4 30.9 27.1 174.8 31.9 34.5 80.9 65.0 32.5 44.3 35.3 34.2 28.1 48.5 90.2 36.0 36.7 35.1 29.4 58.1 42.4 37.9 35.1 200.9 38.0 46.6 38.9 29.8 44.8 56.0 49.2 32.6 52.3 35.5 288.9 47.1 41.5 33.8 32.8 115.6 111.2 99.2 45.6 93.7 88.3 101.5 80.5 85.6 108.0 98.7 160.7 89.1 175.7 78.9 87.7 87.7 83.4 128.9 118.4 131.8 71.4 105.9 139.0 65.6 192.0 95.7 135.9 91.1 100.6 84.0 101.7 119.5 67.2 124.7 99.7 138.4 96.7 105.1 99.0 135.6 140.8 117.8 175.1 88.2 89.9 211.2 158.7 122.5 128.3 119.3 89.0 82.9 124.0 126.3 77.4 70.7 94.6 93.6 76.0 83.6 112.0 101.8 76.6 104.1 119.9 86.9 158.8 94.4 12.1 29.2 12.2 23.5 34.0 20.7 15.9 20.6 19.3 32.9 13.7 18.3 22.3 3.8 20.8 33.2 17.2 23.2 25.4 30.3 31.8 33.1 39.0 31.9 34.5 35.3 34.2 35.1 29.8 32.6 32.8 29.3 54.5 49.2 31.3 42.1 23.3 34.9 51.6 30.1 40.9 21.6 19.7 223.0 24.3 57.3 40.5 33.3 94.9 49.6 57.9 133.1 59.9 152.4 26.5 34.0 38.3 56.0 76.1 41.6 52.8 73.9 36.3 39.8 26.8 48.0 55.6 35.7 64.2 70.9 23.5 46.5 46.2 38.7 49.4 28.3 158.9 27.7 48.9 17.8 26.2 80.6 30.2 52.5 29.1 44.1 43.3 36.3 36.9 56.4 28.6 59.8 92.6 41.8 42.5 6.6 39.7 58.2 100.7 54.6 41.1 24.9 98.5 45.6 118.6 68.0 33.6 MRPL35 ENSG00000132313 "Mitochondrial ribosomal protein L35" Q9NZE8 2 86199355-86213790 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043482 Uncertain "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA043482: AB_10959449" "unprognostic (3.68e-2)" "unprognostic (6.24e-2)" "unprognostic (9.14e-3)" "unprognostic (1.68e-2)" "unprognostic (9.38e-3)" "unprognostic (7.72e-2)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.81e-2)" "unprognostic (1.76e-2)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" "unprognostic (1.66e-1)" "prognostic favorable (9.96e-6)" "unprognostic (1.94e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (2.52e-3)" 25.0 29.7 19.6 24.7 22.0 20.5 25.3 21.2 26.1 18.9 18.8 55.5 57.9 17.8 13.6 31.2 21.9 19.9 83.8 20.1 21.9 47.5 46.1 15.5 35.6 19.7 19.6 17.3 19.7 45.9 12.0 20.9 20.9 19.1 58.7 23.2 24.3 25.1 69.4 14.3 43.3 30.1 20.5 21.6 32.2 16.2 21.7 29.1 19.9 113.5 40.0 32.2 18.0 21.2 83.4 35.8 53.6 55.0 55.1 51.6 77.2 71.5 51.5 88.0 64.9 31.4 69.1 154.1 79.0 61.6 70.9 71.2 109.3 64.2 98.1 89.0 51.0 88.5 25.9 80.5 44.7 143.0 68.0 38.6 75.0 95.4 46.4 42.3 81.4 82.6 111.4 66.1 82.0 50.2 82.0 97.3 56.2 107.0 46.4 71.4 143.1 129.8 90.6 60.2 45.2 43.7 66.1 106.8 116.8 37.5 43.7 57.0 62.2 70.4 85.9 89.8 112.6 49.9 157.4 170.0 61.7 150.1 65.6 30.4 36.0 19.0 21.4 48.4 24.0 45.2 31.9 28.0 41.9 41.4 37.4 29.7 5.1 23.5 50.8 42.2 40.4 32.4 19.6 22.0 21.2 26.1 20.1 21.9 19.7 19.6 20.9 20.5 21.7 21.2 17.3 22.4 15.0 7.2 17.5 7.1 20.3 67.4 11.4 21.9 17.0 20.1 135.9 18.6 42.2 18.4 31.3 49.2 15.0 46.7 97.8 42.0 3.7 22.0 28.3 19.2 26.5 35.1 11.6 43.0 49.7 19.8 23.4 22.1 21.0 21.9 15.7 52.9 65.3 23.5 12.7 31.4 48.8 23.8 6.1 5.0 12.8 23.7 10.6 12.2 32.1 21.5 19.6 5.0 11.5 41.8 29.5 17.7 29.5 17.3 52.6 82.8 24.9 25.4 26.3 17.2 47.2 14.6 26.3 29.0 8.5 27.0 14.6 38.1 56.3 25.2 REEP1 "C2orf23, FLJ13110, SPG31, Yip2a" ENSG00000068615 "Receptor accessory protein 1" Q9H902 2 86213993-86338083 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 86.2;Inhibitory neurons: 95.5;Oligodendrocyte precursor cells: 39.2" "Cancer enhanced" "Detected in many" "glioma: 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 68.1;HAP1: 15.0;RPMI-8226: 16.0;SCLC-21H: 32.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058061 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA058061: AB_2683591" "unprognostic (1.94e-2)" "unprognostic (1.61e-3)" "unprognostic (2.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.29e-2)" "unprognostic (5.10e-2)" "unprognostic (6.63e-2)" "unprognostic (9.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (6.15e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-2)" "unprognostic (6.77e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (1.07e-3)" 4.7 6.2 17.0 1.8 15.8 0.0 4.9 4.1 30.4 3.9 11.5 42.4 4.4 18.9 3.7 6.2 13.6 3.8 16.6 15.4 44.0 2.0 1.1 3.6 0.5 24.6 38.1 1.9 9.9 7.9 13.9 2.2 50.0 7.3 5.0 12.9 1.6 12.9 19.8 2.0 9.3 20.7 4.4 2.0 8.8 44.5 18.7 0.3 2.0 14.3 0.6 21.7 5.8 14.3 0.0 0.0 2.2 2.9 0.1 0.0 68.1 0.0 0.0 4.5 0.5 2.5 0.0 0.0 3.2 0.0 3.4 4.9 15.0 0.1 3.9 0.0 8.1 0.0 5.0 0.4 0.0 0.3 0.4 0.7 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.0 0.1 2.7 0.1 0.0 2.6 0.1 0.0 0.1 6.5 16.0 0.3 0.3 32.0 3.1 3.5 1.6 0.2 1.3 5.1 0.9 0.0 0.0 2.3 1.3 6.3 7.2 5.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 15.8 4.1 30.4 15.4 44.0 24.6 38.1 50.0 4.4 18.7 14.3 1.7 9.6 0.5 14.7 0.2 2.0 0.3 0.3 0.0 10.0 3.6 1.1 23.0 2.8 2.8 0.0 2.1 2.4 0.0 0.4 1.9 3.5 18.0 17.1 0.3 5.7 4.8 0.0 86.2 6.2 26.6 2.4 0.0 0.7 0.0 0.8 12.5 0.2 0.9 3.3 95.5 0.2 8.2 0.8 1.6 14.4 2.5 0.4 1.8 6.5 0.6 13.4 0.0 39.2 6.0 6.5 0.0 3.4 0.0 1.6 0.0 5.1 16.6 15.8 19.7 4.2 13.5 4.0 2.7 0.5 1.1 6.6 0.2 0.0 0.5 0.4 KDM3A "JHMD2A, JMJD1, JMJD1A, KIAA0742, TSGA" ENSG00000115548 "Lysine demethylase 3A" Q9Y4C1 2 86440647-86492716 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055543, HPA065162" Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA055543: AB_2682842, HPA065162: AB_2685424" "unprognostic (1.97e-2)" "unprognostic (3.03e-3)" "unprognostic (1.32e-2)" "unprognostic (4.04e-2)" "unprognostic (5.06e-2)" "unprognostic (5.24e-2)" "prognostic unfavorable (2.15e-6)" "unprognostic (2.01e-1)" "unprognostic (3.35e-3)" "unprognostic (9.50e-3)" "unprognostic (4.44e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (2.17e-1)" "unprognostic (2.24e-1)" "unprognostic (1.24e-1)" "unprognostic (2.66e-2)" 21.2 12.9 17.9 13.1 19.0 70.3 19.9 17.5 18.9 18.0 18.6 25.0 18.9 20.7 18.2 20.8 18.4 15.9 21.7 15.3 18.1 15.4 12.9 16.7 17.9 18.1 17.4 21.5 16.1 14.6 12.8 22.1 17.8 16.6 15.9 54.7 19.8 19.7 21.5 38.6 20.1 15.0 16.6 18.4 14.9 50.9 18.7 27.4 20.0 21.4 19.6 20.8 20.2 20.1 34.7 13.5 31.5 8.3 15.9 16.1 29.4 16.5 16.2 15.1 18.5 17.3 14.3 20.1 30.4 13.8 31.1 21.5 23.7 16.6 29.2 27.1 19.7 32.4 12.6 24.8 11.9 26.1 19.9 17.8 24.5 13.6 24.9 51.9 19.0 18.5 21.1 31.9 16.1 8.9 36.2 36.4 28.3 20.6 20.4 24.5 42.6 44.0 13.6 19.2 24.4 25.9 21.7 15.5 30.2 27.5 9.0 16.8 21.2 30.6 12.6 31.8 19.1 33.3 33.9 29.6 38.8 26.6 38.2 16.9 3.0 5.8 6.7 3.3 7.1 4.2 7.5 6.6 4.6 3.6 7.9 7.0 13.4 5.0 2.2 4.2 8.3 3.9 17.9 19.0 17.5 18.9 15.3 18.1 18.1 17.4 17.8 16.6 18.7 20.1 26.0 35.3 17.0 56.8 19.7 30.5 23.2 19.5 43.3 24.0 18.9 14.6 30.3 7.2 24.8 5.5 52.1 5.2 29.2 24.2 0.0 12.1 82.0 36.6 15.6 23.4 15.6 21.0 28.7 9.8 8.5 19.1 23.0 35.5 38.6 11.9 15.4 7.6 10.4 55.5 27.4 13.7 26.4 10.9 18.2 29.7 17.4 17.5 21.4 28.1 8.6 36.0 21.6 26.2 23.5 11.3 8.0 17.3 21.4 16.0 23.0 5.6 44.1 34.4 6.6 21.3 20.4 38.7 14.1 35.5 40.1 11.6 27.4 15.2 10.7 13.6 CHMP3 "CGI-149, NEDF, VPS24" ENSG00000115561 "Charged multivesicular body protein 3" Q9Y3E7 2 86503430-86563479 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA015673, HPA073383" Supported NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA015673: AB_1858761, HPA073383: AB_2732224" "unprognostic (2.49e-3)" "unprognostic (1.32e-1)" "unprognostic (7.29e-2)" "unprognostic (1.35e-2)" "unprognostic (2.13e-1)" "unprognostic (2.83e-2)" "prognostic unfavorable (3.92e-5)" "unprognostic (2.67e-1)" "unprognostic (6.16e-2)" "unprognostic (8.40e-2)" "prognostic unfavorable (7.39e-4)" "unprognostic (1.20e-1)" "prognostic favorable (5.32e-4)" "unprognostic (1.34e-1)" "unprognostic (8.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.64e-1)" 70.0 56.1 39.5 41.0 54.3 30.9 64.2 49.3 45.6 57.9 26.1 72.3 63.1 68.8 56.9 93.0 51.8 54.8 100.2 46.3 39.9 59.9 23.3 64.0 34.0 35.9 36.5 49.0 66.7 70.3 33.1 31.8 37.1 64.3 75.9 30.8 52.9 61.9 97.1 58.6 64.5 73.4 38.7 40.3 60.5 34.2 42.5 31.7 68.0 80.9 39.9 70.2 50.6 38.1 105.3 96.1 54.4 39.6 71.2 136.7 52.5 76.7 103.2 64.4 55.6 86.2 90.2 34.3 71.7 97.7 71.8 82.8 33.3 67.0 70.3 21.0 42.5 45.5 45.5 98.8 62.5 36.4 47.7 82.4 147.7 40.8 64.9 70.4 73.1 34.1 49.1 25.3 104.7 90.7 24.4 32.4 18.8 138.9 73.8 15.3 125.2 27.2 85.7 117.3 65.7 71.4 73.3 68.0 66.1 25.8 58.3 55.7 88.7 114.2 46.8 112.2 86.7 21.0 33.1 22.9 81.5 58.0 61.3 158.5 61.5 171.5 28.0 73.8 33.6 49.5 41.8 33.8 49.9 49.3 48.7 37.9 228.7 35.5 66.5 42.1 46.1 54.4 39.5 54.3 49.3 45.6 46.3 39.9 35.9 36.5 37.1 38.7 42.5 38.1 102.5 147.4 93.5 0.0 49.6 95.3 83.3 94.4 83.6 55.7 115.2 72.6 125.2 147.3 111.4 40.5 41.7 51.1 42.7 222.1 148.7 180.7 206.6 46.7 84.9 96.2 133.5 73.0 0.0 174.8 59.2 67.4 58.6 70.4 147.6 30.0 144.5 59.1 89.5 69.0 0.0 159.2 65.1 126.2 48.4 108.5 71.7 77.2 71.2 0.0 93.6 60.5 78.2 0.0 0.0 186.7 219.4 91.0 25.0 95.9 201.1 173.3 76.1 42.4 65.7 73.6 78.5 100.7 57.3 101.9 94.1 85.0 47.5 57.3 165.4 103.4 RNF103-CHMP3 RNF103-VPS24 ENSG00000249884 "RNF103-CHMP3 readthrough" 2 86505668-86721122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.3;brain: 3.9;heart muscle: 4.1" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Excitatory neurons: 17.6;Inhibitory neurons: 12.3;Microglial cells: 6.5;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 11.4" "HPA015673, HPA073383" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA015673: AB_1858761, HPA073383: AB_2732224" "unprognostic (3.77e-2)" "unprognostic (5.47e-2)" "unprognostic (8.91e-4)" "unprognostic (9.64e-3)" "unprognostic (1.39e-1)" "unprognostic (8.67e-2)" "unprognostic (1.03e-4)" "unprognostic (3.21e-3)" "unprognostic (1.00e-1)" "unprognostic (7.56e-2)" "unprognostic (5.83e-3)" "unprognostic (7.12e-2)" "unprognostic (8.90e-3)" "unprognostic (4.68e-2)" "unprognostic (6.56e-2)" "unprognostic (6.45e-2)" "unprognostic (6.94e-3)" 0.4 0.3 1.1 0.9 1.4 4.3 1.1 3.6 3.9 0.4 0.0 0.5 0.7 0.4 0.0 0.7 0.6 0.4 4.1 1.6 0.4 0.2 0.4 0.2 0.3 2.0 0.7 0.3 0.1 0.3 0.2 0.6 1.0 0.4 0.3 0.4 0.1 0.4 2.2 0.3 0.3 0.3 0.4 0.3 0.9 1.2 0.8 0.6 0.2 0.5 0.5 0.1 0.2 1.9 1.5 0.4 0.9 1.0 1.0 0.0 1.6 1.2 0.6 0.7 1.0 1.3 2.0 2.3 0.8 0.7 11.4 0.6 0.3 0.3 0.2 1.6 0.6 0.8 0.0 1.0 0.2 1.0 1.3 0.8 0.2 0.4 1.1 1.1 0.1 2.5 0.9 1.2 1.3 0.3 2.0 1.0 0.0 0.6 0.2 4.7 2.1 0.1 0.1 1.2 1.7 1.5 1.7 1.8 0.7 0.2 0.2 1.2 0.5 0.6 3.9 0.8 0.9 1.8 0.4 2.1 0.8 1.4 0.2 0.0 0.3 0.2 0.1 0.4 0.5 1.3 0.3 0.4 0.4 1.7 0.1 0.1 2.0 0.7 0.0 1.8 0.2 0.2 1.1 1.4 3.6 3.9 1.6 0.4 2.0 0.7 1.0 0.4 0.8 1.9 0.0 0.0 1.1 5.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 1.3 17.6 0.4 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 6.5 0.0 0.0 1.0 10.1 4.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 RNF103 "hkf-1, KF1, ZFP103" ENSG00000239305 "Ring finger protein 103" O00237 2 86603398-86623866 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057922 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "HPA057922: AB_2683555" "unprognostic (4.41e-1)" "unprognostic (1.56e-1)" "unprognostic (6.04e-2)" "unprognostic (3.26e-1)" "unprognostic (3.20e-2)" "unprognostic (1.79e-1)" "unprognostic (7.42e-2)" "unprognostic (8.37e-2)" "unprognostic (4.06e-1)" "unprognostic (1.13e-2)" "unprognostic (6.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.54e-3)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (3.67e-2)" "prognostic favorable (6.77e-5)" 14.6 15.3 25.7 9.0 28.8 13.6 20.9 35.8 31.6 15.9 22.6 21.9 18.7 23.7 45.4 14.0 16.9 19.4 37.7 24.8 25.1 15.3 54.5 11.3 8.1 26.8 27.2 16.0 24.7 25.2 15.6 15.6 25.7 23.3 16.5 10.3 18.7 17.7 21.4 14.3 23.0 21.0 27.2 10.5 22.6 15.4 26.7 8.1 10.2 19.1 10.0 14.4 13.9 30.6 9.6 12.9 6.4 9.9 28.6 18.3 10.3 13.6 20.6 6.8 9.2 7.5 16.1 15.9 15.9 20.4 24.8 11.5 8.7 10.7 10.2 13.4 11.7 9.1 5.4 16.7 27.1 3.0 13.0 26.9 21.8 10.1 12.6 24.3 20.7 7.4 3.3 9.3 19.0 11.9 7.0 8.0 2.9 19.0 9.0 4.3 27.5 9.4 25.1 14.9 10.2 10.4 16.0 35.2 14.0 8.0 13.5 7.4 23.6 13.2 6.3 13.4 8.2 32.3 11.5 10.7 10.5 5.1 6.5 4.5 0.5 7.2 0.7 0.7 1.0 0.9 1.1 1.6 1.1 1.0 1.2 0.9 1.0 2.3 0.4 0.8 2.5 0.6 25.7 28.8 35.8 31.6 24.8 25.1 26.8 27.2 25.7 27.2 26.7 30.6 22.6 9.6 14.5 0.0 16.6 48.3 35.5 13.9 33.6 15.8 45.9 31.1 40.0 31.5 22.1 20.2 4.2 13.6 15.7 72.4 1.9 17.6 16.8 20.4 17.9 22.4 31.8 16.4 0.0 28.4 7.8 27.6 44.4 30.0 18.4 19.9 22.9 68.9 9.6 18.5 0.0 45.9 12.2 14.1 29.5 9.3 25.4 19.8 10.6 0.0 8.0 17.2 2.1 0.0 0.0 33.9 41.5 23.0 41.1 45.0 56.1 12.9 33.6 9.5 6.6 40.3 25.7 27.5 12.6 32.6 44.2 40.9 19.5 9.0 24.3 48.6 RMND5A "FLJ13910, GID2, GID2A, p44CTLH, RMD5" ENSG00000153561 "Required for meiotic nuclear division 5 homolog A" Q9H871 2 86720291-86778041 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046795, HPA060843" Uncertain Supported Nucleoplasm NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA046795: AB_10963573, HPA060843: AB_2684378" "unprognostic (4.54e-2)" "unprognostic (9.23e-2)" "unprognostic (3.45e-2)" "prognostic unfavorable (3.03e-4)" "unprognostic (2.32e-2)" "unprognostic (4.40e-2)" "unprognostic (1.52e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (1.49e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-2)" "unprognostic (8.34e-3)" "unprognostic (1.41e-1)" "unprognostic (1.47e-1)" "unprognostic (1.56e-1)" 17.8 11.2 19.4 9.3 24.3 31.2 16.2 54.5 25.2 13.4 20.0 19.7 16.4 13.0 13.3 31.3 12.9 6.8 38.2 21.6 17.5 18.2 42.9 10.5 11.6 18.4 20.6 11.1 11.6 20.8 7.9 11.6 18.3 12.4 21.2 18.9 11.4 11.1 63.6 22.4 15.5 13.7 20.4 14.3 12.1 7.8 18.7 31.4 13.0 37.0 14.0 10.0 17.0 28.8 19.4 10.2 17.6 10.5 22.9 10.1 36.3 7.5 6.1 9.7 11.0 37.6 20.3 66.7 22.4 6.9 11.3 22.6 45.1 15.8 15.0 19.4 34.4 58.7 21.8 34.2 23.1 43.2 18.6 15.4 30.5 10.2 35.2 11.0 17.0 48.7 37.7 37.3 7.9 12.6 40.1 36.9 29.8 23.1 13.0 47.3 54.2 42.3 20.1 22.8 32.6 25.1 16.9 33.5 27.9 24.8 16.8 36.8 16.3 6.7 12.9 12.2 11.7 16.7 18.8 45.0 5.6 51.3 7.8 37.5 11.9 8.1 8.1 10.1 9.7 4.7 6.2 9.1 9.4 6.4 8.4 11.6 27.5 8.8 12.5 7.4 4.7 8.6 19.4 24.3 54.5 25.2 21.6 17.5 18.4 20.6 18.3 20.4 18.7 28.8 32.8 12.8 15.9 15.3 27.0 41.9 23.4 10.4 46.7 26.3 25.5 15.6 93.2 24.3 10.5 11.0 6.2 21.0 36.2 73.3 23.5 13.1 13.7 33.8 28.7 26.0 39.5 105.2 27.3 14.1 18.6 20.1 24.5 35.3 8.2 16.3 25.0 76.7 15.1 23.5 27.2 57.4 14.2 34.4 42.7 5.6 19.3 26.3 32.0 14.0 23.7 15.3 30.9 10.6 42.3 21.9 30.9 17.3 30.1 34.8 38.1 34.4 26.6 16.3 6.6 22.7 20.1 17.9 27.8 50.0 54.8 24.6 31.4 24.6 28.7 34.0 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 RGPD1 RGP1 ENSG00000187627 "RANBP2 like and GRIP domain containing 1" P0DJD0 2 86907953-87013976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.6;placenta: 6.8;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Early spermatids: 2.5;Excitatory neurons: 4.3;granulocytes: 3.8;Inhibitory neurons: 4.0;Microglial cells: 2.8;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.6;MOLT-4: 10.7;NTERA-2: 3.1;RPMI-8226: 2.4;SuSa: 5.3" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (8.24e-2)" "unprognostic (6.05e-2)" "unprognostic (6.41e-2)" "unprognostic (1.39e-2)" "unprognostic (9.06e-2)" "unprognostic (6.28e-2)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.88e-5)" "unprognostic (2.23e-1)" "unprognostic (2.22e-2)" "unprognostic (5.36e-3)" "unprognostic (1.99e-2)" 0.1 0.1 0.2 0.1 0.2 0.0 0.1 2.0 0.4 8.6 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.1 0.6 0.1 0.1 0.1 0.2 1.5 0.3 0.1 1.6 0.3 1.5 6.8 1.2 0.1 0.0 2.1 0.2 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.3 15.4 0.6 0.9 0.2 0.0 0.5 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 10.7 0.2 3.1 0.1 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.7 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.0 0.4 0.1 0.6 1.5 0.3 1.2 0.1 0.6 0.3 0.1 0.0 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.0 0.4 4.3 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 1.5 1.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.2 0.8 0.0 0.0 0.3 1.0 0.0 0.0 0.0 PLGLB1 "PLGL, PRP-B" ENSG00000183281 "Plasminogen like B1" Q02325 2 87002559-87021852 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in all" 6 "liver: 234.9" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 95.9" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Secreted to blood" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 15: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (1.75e-2)" "unprognostic (1.39e-5)" "unprognostic (7.04e-3)" "unprognostic (1.15e-1)" "unprognostic (8.53e-4)" "unprognostic (1.60e-1)" "unprognostic (4.56e-4)" "unprognostic (9.90e-3)" "unprognostic (2.96e-5)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (4.32e-2)" "unprognostic (3.98e-5)" 3.6 5.5 19.9 4.5 19.9 8.5 3.6 33.4 26.5 6.9 21.3 4.9 3.9 5.9 8.2 4.0 4.3 4.7 5.9 20.0 20.3 8.5 234.9 3.3 7.9 16.7 17.4 6.7 4.1 2.2 9.5 2.3 16.0 6.6 2.7 42.5 4.8 3.2 8.8 14.2 5.3 2.4 15.0 9.5 4.0 4.3 20.0 7.2 5.6 4.4 4.3 4.9 4.9 19.6 2.7 3.7 4.6 2.6 3.6 5.2 4.5 3.2 2.3 1.7 2.6 2.9 6.9 7.3 3.3 1.3 1.3 2.4 1.2 0.5 1.8 8.2 3.1 5.8 6.6 3.1 2.5 3.5 1.5 4.0 4.2 4.7 4.8 7.9 0.8 8.0 3.0 5.9 2.2 3.9 13.3 11.5 5.9 2.4 2.4 3.1 1.7 3.9 4.5 2.9 3.6 4.0 2.9 2.5 2.7 4.6 1.3 7.6 5.0 3.3 2.3 2.3 2.0 6.7 5.1 2.9 1.9 4.7 1.9 1.9 0.3 0.4 0.7 0.1 0.6 1.2 0.7 0.5 0.1 0.8 0.9 0.5 1.0 0.4 0.3 0.6 1.1 0.1 19.9 19.9 33.4 26.5 20.0 20.3 16.7 17.4 16.0 15.0 20.0 19.6 1.3 0.0 3.4 0.7 1.0 1.1 0.3 0.4 1.2 10.3 1.1 1.0 2.6 1.5 1.5 0.0 6.2 0.2 1.5 0.7 0.0 1.1 0.8 1.0 1.0 1.6 1.2 4.0 0.9 0.2 0.2 1.6 0.5 0.9 0.0 1.0 1.8 95.9 0.2 5.0 1.1 2.5 0.0 1.3 0.4 0.3 1.2 1.1 3.6 0.0 1.6 2.7 1.0 0.0 0.8 0.3 0.3 1.9 0.9 0.5 0.7 1.8 2.3 18.2 0.0 2.5 1.0 0.7 0.5 1.5 1.3 0.0 1.4 0.9 0.9 0.3 IGKV3OR2-268 "IGKV268, IGKV3/OR2-268, IGKV3/OR2-268A, IGKV3OR2-268A" ENSG00000233999 "Immunoglobulin kappa variable 3/OR2-268 (non-functional)" 2 87338511-87339035 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 100.4;lymphoid tissue: 85.7" "Cell type enriched" "Detected in some" 302 "Plasma cells: 2604.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 220.0;naive B-cell: 78.9" "Lineage enriched" "Detected in many" 7 "B-cells: 220.0" "Group enriched" "Detected in some" 71 "U-266/70: 183.9;U-266/84: 593.2" HPA047702 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (8.06e-4)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.26e-1)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (8.68e-2)" "unprognostic (2.61e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.12e-6)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (1.58e-1)" "unprognostic (4.41e-1)" 0.4 1.3 0.3 45.8 0.4 11.8 28.5 0.1 0.6 3.4 0.2 100.4 33.9 0.9 0.0 1.3 0.7 24.7 1.3 0.3 0.4 0.6 2.6 7.5 23.8 0.3 0.2 3.3 1.2 0.0 0.0 0.1 0.2 1.6 59.5 0.0 29.4 1.6 0.0 0.6 27.7 4.1 0.1 19.3 34.0 0.4 0.2 10.3 1.2 0.0 85.7 24.4 0.8 0.5 0.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.5 0.2 183.9 593.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 220.0 2.8 0.1 0.1 78.9 0.0 0.1 0.1 0.1 0.0 0.2 30.0 32.7 0.3 0.4 0.1 0.6 0.3 0.4 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2604.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 PLGLB2 PLGP1 ENSG00000125551 "Plasminogen like B2" Q02325 2 87748087-87759476 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in some" 163 "liver: 454.4" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 76.3" "Cancer enriched" "Detected in single" 25 "liver cancer: 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (1.10e-2)" "unprognostic (8.78e-2)" "unprognostic (3.42e-2)" "unprognostic (7.03e-4)" "unprognostic (1.68e-2)" "unprognostic (3.77e-1)" "unprognostic (1.82e-2)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (5.04e-4)" "unprognostic (6.39e-2)" "unprognostic (4.06e-2)" "unprognostic (3.22e-2)" "unprognostic (7.11e-2)" 0.4 0.8 1.0 0.5 0.7 0.5 0.3 2.0 1.0 0.8 0.2 0.3 0.2 0.6 0.6 0.6 0.7 0.2 0.8 0.9 0.1 0.9 454.4 0.3 0.9 0.2 0.3 0.5 1.3 0.4 0.9 0.4 0.2 0.7 0.3 2.7 0.4 0.4 0.6 1.0 0.5 0.2 0.1 0.9 0.5 1.0 0.2 0.8 0.5 0.5 0.7 0.3 0.2 0.6 0.0 0.1 1.2 0.3 0.4 0.5 0.4 0.6 0.4 0.1 0.2 0.1 0.3 0.7 0.4 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.5 1.2 0.0 0.1 0.5 0.2 0.5 0.3 0.1 0.2 1.0 0.4 0.7 0.0 0.1 0.4 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.0 0.4 0.0 0.0 0.7 0.2 0.2 0.0 0.3 0.0 0.3 0.2 0.1 0.5 0.4 0.3 0.5 1.2 0.3 0.4 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.0 0.1 0.0 1.0 0.7 2.0 1.0 0.9 0.1 0.2 0.3 0.2 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.5 4.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.0 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 76.3 0.1 0.0 0.3 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 RGPD2 "RANBP2L2, RGP2" ENSG00000185304 "RANBP2 like and GRIP domain containing 2" P0DJD1 2 87755960-87825952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.0;dendritic cells: 5.1;Early spermatids: 5.5;Excitatory neurons: 4.3;Late spermatids: 6.7;Plasma cells: 7.5;T-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.6" "Lineage enriched" "Detected in single" 11 "T-cells: 9.6" "Cell line enhanced" "Detected in some" "BEWO: 11.0;JURKAT: 5.4;MOLT-4: 13.3;NTERA-2: 5.4;SuSa: 15.2;THP-1: 5.2" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (4.49e-2)" "unprognostic (1.99e-1)" "unprognostic (1.26e-2)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (7.46e-3)" "unprognostic (1.71e-1)" "unprognostic (1.72e-2)" "unprognostic (4.10e-2)" "unprognostic (4.24e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-6)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (5.09e-2)" "unprognostic (2.59e-1)" 1.8 2.8 0.8 1.3 0.7 8.9 1.4 2.6 1.4 10.5 1.6 1.7 2.0 1.4 0.4 0.9 3.2 0.4 1.2 0.6 0.6 1.2 9.6 2.6 2.2 1.7 0.8 2.6 7.9 0.3 5.8 9.5 2.0 1.7 0.7 3.4 1.3 0.7 1.0 1.2 3.7 0.5 0.4 3.2 2.7 16.6 1.0 5.6 1.8 0.3 2.5 0.8 1.6 0.7 0.0 0.0 0.6 0.0 0.0 0.0 11.0 0.5 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 2.6 0.2 0.0 0.1 0.0 5.4 4.0 0.3 0.0 0.4 13.3 0.0 5.4 2.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 2.7 4.5 0.1 0.0 15.2 0.0 5.2 0.1 0.8 0.1 0.0 0.0 2.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.3 0.6 2.1 0.4 0.0 0.8 1.0 0.2 0.3 0.1 0.0 0.0 9.6 0.3 0.8 0.7 2.6 1.4 0.6 0.6 1.7 0.8 2.0 0.4 1.0 0.7 0.9 0.0 1.1 1.0 4.0 0.1 0.0 0.0 0.0 0.5 0.1 0.3 7.0 0.0 0.0 0.0 0.0 0.4 5.1 0.2 0.0 0.1 5.5 1.7 2.3 0.7 0.0 0.0 4.3 0.2 0.6 0.9 0.5 0.7 0.0 0.2 0.4 0.3 0.1 0.0 3.4 0.0 0.0 0.0 0.4 6.7 0.0 1.7 0.0 1.9 0.0 0.0 0.0 1.5 2.2 0.1 0.0 0.0 7.5 0.1 0.0 0.1 0.8 1.7 0.0 1.0 0.8 2.5 0.6 0.0 0.0 1.0 4.5 0.1 0.0 0.0 KRCC1 FLJ22333 ENSG00000172086 "Lysine rich coiled-coil 1" Q9NPI7 2 88027205-88064252 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045618, HPA052666" Approved Approved Nucleoli,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Nucleoli "HPA045618: AB_10960406, HPA052666: AB_2681907" "unprognostic (7.37e-3)" "unprognostic (1.30e-1)" "unprognostic (2.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (2.59e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "unprognostic (4.83e-2)" "unprognostic (2.22e-1)" "unprognostic (6.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-3)" 28.2 21.0 20.1 28.7 22.8 10.1 38.4 21.7 28.0 33.0 20.7 45.9 32.0 23.9 41.7 32.2 27.1 22.2 31.7 19.9 21.6 31.9 43.6 21.9 38.0 23.2 22.0 24.6 28.6 34.1 15.7 21.9 23.7 25.2 43.8 14.5 24.8 26.0 29.1 25.8 35.7 22.9 21.8 30.7 27.2 15.2 21.7 31.5 33.2 34.6 32.4 24.4 24.9 24.9 29.4 17.8 27.4 20.1 64.1 75.3 20.2 45.5 50.3 23.7 23.1 1.6 38.5 41.4 16.0 28.9 36.1 14.8 6.3 9.4 26.7 43.7 8.7 8.0 4.4 2.8 46.7 12.2 5.5 38.0 46.3 15.9 33.7 61.9 27.1 32.9 11.5 20.2 51.7 25.0 14.1 16.9 20.9 42.3 11.8 28.3 5.0 4.5 36.0 15.8 21.1 21.3 17.3 23.7 54.8 20.1 16.7 49.2 38.2 28.0 2.1 46.5 14.5 45.3 33.6 32.5 30.1 32.0 67.5 59.4 21.6 77.7 18.8 23.8 21.7 36.6 23.0 23.2 25.7 32.5 25.8 21.0 35.8 31.6 21.5 22.5 34.3 16.8 20.1 22.8 21.7 28.0 19.9 21.6 23.2 22.0 23.7 21.8 21.7 24.9 24.2 35.3 41.7 29.4 61.8 33.0 32.6 49.9 53.5 11.9 50.9 50.9 41.3 40.0 49.0 35.0 2.1 46.1 24.8 109.1 60.7 50.5 16.7 34.4 37.8 31.6 41.6 28.2 14.5 70.9 16.3 42.5 17.3 30.9 43.1 28.4 37.9 59.5 48.6 10.1 13.9 56.8 26.4 40.3 39.8 5.3 47.8 38.8 28.4 44.0 53.6 35.9 58.7 34.7 53.5 51.4 79.6 43.2 29.6 62.6 60.4 76.0 62.6 5.4 19.7 40.3 29.7 41.0 20.7 45.4 42.6 41.9 37.2 32.2 72.4 26.4 SMYD1 "BOP, KMT3D, ZMYND22" ENSG00000115593 "SET and MYND domain containing 1" Q8NB12 2 88067825-88113384 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "heart muscle: 160.4;skeletal muscle: 493.6;tongue: 301.3" "Cell type enriched" "Detected in some" 27 "Cardiomyocytes: 208.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.9;stomach cancer: 1.6" "Region enriched" "Detected in some" 4 "basal ganglia: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HSkMC: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA062282 Enhanced NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA062282: AB_2684736" "unprognostic (1.93e-2)" "unprognostic (2.49e-1)" "unprognostic (4.09e-2)" "unprognostic (8.51e-3)" "unprognostic (2.74e-1)" "unprognostic (3.91e-1)" "unprognostic (8.81e-3)" "unprognostic (1.40e-1)" 0.0 0.0 0.2 0.2 4.1 0.0 5.4 0.1 1.0 0.0 0.0 17.9 2.0 0.0 0.0 7.3 0.0 0.0 160.4 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 2.4 0.0 0.0 0.3 4.0 1.9 0.0 3.9 0.0 493.6 0.1 7.0 28.1 0.1 0.0 7.3 0.3 0.1 0.4 0.1 301.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.1 0.1 1.0 0.4 0.1 0.1 0.2 0.3 0.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.7 208.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 1.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "intestine: 5501.2;liver: 13065.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 12424.2;Hepatocytes: 7459.2;Paneth cells: 3975.2;Proximal enterocytes: 15929.5" "Group enriched" "Detected in many" 14 "colorectal cancer: 175.1;liver cancer: 437.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 122.1;Hep G2: 393.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 45000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cytosol" "CAB002305: AB_563728, HPA028275: AB_10600909" "unprognostic (1.91e-1)" "unprognostic (7.91e-3)" "unprognostic (5.47e-2)" "unprognostic (1.96e-1)" "unprognostic (2.03e-2)" "unprognostic (2.35e-1)" "unprognostic (7.99e-2)" "unprognostic (8.92e-2)" "unprognostic (2.29e-1)" 6.7 0.8 0.6 160.2 0.6 0.0 10.7 0.5 1.8 0.7 0.4 5501.2 4751.8 13.0 0.0 2.6 3.9 0.5 0.8 0.6 0.7 727.6 13065.3 0.9 3.7 0.6 0.5 0.9 1.0 0.3 0.8 0.7 0.5 2.6 3416.4 0.1 0.5 8.4 0.9 0.5 4727.6 230.4 0.5 2.8 15.8 1.1 0.6 0.1 0.5 0.4 0.1 0.6 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 33.3 0.0 0.0 0.0 0.0 122.1 0.0 1.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.2 0.0 393.9 0.0 7.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 33.0 0.5 0.0 0.0 0.3 6.4 37.4 0.0 0.5 3.6 24.7 2.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 11.8 0.7 0.4 0.1 2.5 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.8 0.6 0.7 0.6 0.5 0.5 0.5 0.6 0.7 0.0 0.0 0.0 0.3 42.6 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.3 120.1 0.0 60.7 0.0 0.2 0.0 12424.2 156.5 0.0 0.0 0.0 0.0 7.5 261.9 149.7 0.1 0.0 1.2 0.1 2.6 0.0 129.2 0.0 105.3 7459.2 1.5 0.0 0.1 1061.1 0.0 166.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3975.2 0.0 0.0 0.1 15929.5 2014.4 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.0 1.4 29.3 0.0 1708.4 0.0 THNSL2 "FLJ10916, SOFAT, TSH2" ENSG00000144115 "Threonine synthase like 2" Q86YJ6 2 88170295-88186636 "Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 58.7;Proximal tubular cells: 87.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 31.6;MCF7: 12.2;SK-MEL-30: 12.6;SuSa: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035395 Approved "Secreted - unknown location" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035395: AB_10601600" "unprognostic (1.51e-2)" "unprognostic (1.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (8.73e-2)" "unprognostic (6.64e-2)" "unprognostic (7.26e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-2)" "unprognostic (2.01e-3)" "unprognostic (6.98e-2)" "unprognostic (8.81e-2)" "unprognostic (1.40e-1)" "unprognostic (1.24e-2)" 13.9 22.6 14.9 2.4 16.9 0.9 16.4 15.1 15.6 14.8 15.0 18.0 5.6 11.2 22.6 6.5 19.2 7.7 17.8 13.8 18.1 28.5 50.0 7.2 1.9 16.7 16.2 14.9 14.2 32.3 29.1 8.6 16.0 22.3 3.7 7.3 12.9 13.5 50.1 9.3 12.6 6.3 16.1 7.5 13.5 13.0 16.7 1.1 21.9 35.8 1.8 12.5 9.9 16.3 0.3 0.0 0.0 0.0 2.7 0.9 1.5 4.6 5.0 6.4 8.3 6.6 7.7 0.0 2.2 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.0 0.0 0.0 31.6 0.0 0.6 5.1 10.3 1.9 0.0 0.5 0.0 0.0 0.0 0.0 4.7 12.2 0.0 0.1 6.2 7.1 0.6 0.0 0.0 0.0 5.2 0.5 0.3 0.0 5.4 0.4 12.6 15.0 8.8 2.0 0.0 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.2 0.3 0.3 0.4 0.2 0.4 0.1 0.2 0.4 0.7 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 14.9 16.9 15.1 15.6 13.8 18.1 16.7 16.2 16.0 16.1 16.7 16.3 2.8 3.2 9.3 13.1 3.1 6.6 8.6 8.3 9.6 12.8 23.2 20.2 17.3 20.0 2.9 14.7 0.0 42.5 0.4 9.2 58.7 14.8 1.3 14.5 8.9 3.6 2.4 6.1 2.8 3.0 15.7 13.8 6.6 8.4 0.0 8.1 7.9 43.6 4.6 13.5 3.0 6.8 4.1 10.7 4.6 4.2 9.0 2.8 14.2 5.6 11.3 43.5 3.1 4.0 16.7 5.4 8.9 9.8 1.7 6.3 13.4 87.2 5.2 7.3 0.0 8.9 6.4 3.7 11.4 3.7 5.1 23.9 1.7 13.8 6.2 5.6 FOXI3 ENSG00000214336 "Forkhead box I3" A8MTJ6 2 88446787-88452693 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "placenta: 5.2;retina: 2.0" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 3.3;Muller glia cells: 6.4;Syncytiotrophoblasts: 2.7" "Cancer enriched" "Detected in some" 5 "testis cancer: 10.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 43.2;SuSa: 55.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (2.72e-1)" "unprognostic (1.20e-1)" "unprognostic (2.92e-1)" "unprognostic (6.72e-4)" "unprognostic (8.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.58e-2)" "unprognostic (5.29e-2)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 5.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 43.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.5 0.0 0.0 0.0 55.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.5 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.7 0.0 0.0 0.0 0.0 TEX37 "C2orf51, FLJ25369, TSC21" ENSG00000172073 "Testis expressed 37" Q96LM6 2 88524649-88529585 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 640 "testis: 85.0" "Group enriched" "Detected in some" 229 "Early spermatids: 846.6;Late spermatids: 3191.0" "Cancer enriched" "Detected in single" 17 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 31 "BEWO: 50.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA043987, HPA070239" Enhanced Supported Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA043987: AB_10961125, HPA070239: " "unprognostic (1.08e-3)" "unprognostic (2.24e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 50.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 846.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3191.0 8.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.4 8.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 EIF2AK3 "PEK, PERK" ENSG00000172071 "Eukaryotic translation initiation factor 2 alpha kinase 3" Q9NZJ5 2 88556741-88627464 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Stress response, Translation regulation, Unfolded protein response" "Kinase, Serine/threonine-protein kinase, Transferase" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 19.6" "Cell type enhanced" "Detected in many" "Plasma cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 46.8;U-266/70: 44.0;U-698: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009204, HPA015737" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB009204: AB_2230863, HPA015737: AB_1848062" "unprognostic (7.25e-3)" "unprognostic (5.35e-2)" "unprognostic (3.03e-3)" "unprognostic (9.32e-2)" "unprognostic (9.39e-3)" "unprognostic (3.25e-2)" "unprognostic (2.27e-2)" "unprognostic (3.46e-3)" "unprognostic (9.84e-2)" "unprognostic (3.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.31e-1)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (9.80e-2)" "unprognostic (3.60e-3)" "unprognostic (2.90e-3)" 3.3 3.1 0.8 4.0 1.1 2.6 1.6 1.6 1.4 2.3 1.6 4.7 6.2 1.9 1.0 1.6 1.3 1.4 1.5 0.8 1.5 2.0 1.9 1.8 3.2 1.0 1.2 1.9 19.6 3.4 1.1 3.2 0.9 4.0 1.8 0.1 9.7 1.2 2.0 1.4 5.0 0.9 1.5 3.1 12.3 1.0 1.2 1.3 3.5 0.0 2.3 1.9 1.8 2.1 8.7 3.3 1.2 4.3 2.8 2.0 15.9 12.4 1.1 0.7 2.1 3.5 2.9 46.8 8.0 1.3 3.1 7.2 1.6 1.3 1.1 25.3 7.1 4.6 1.7 2.0 1.1 3.9 12.3 0.1 1.5 0.7 2.0 0.8 1.4 4.9 3.0 8.7 0.6 4.4 5.5 2.2 6.2 2.7 7.2 25.1 7.0 8.2 1.3 5.0 5.6 9.9 6.3 6.5 8.2 1.7 2.2 4.4 3.9 2.5 5.5 10.8 7.1 44.0 24.4 31.0 4.6 4.2 6.2 0.0 0.1 0.1 0.3 0.0 0.2 1.0 0.2 0.8 0.1 1.9 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 1.1 1.6 1.4 0.8 1.5 1.0 1.2 0.9 1.5 1.2 2.1 9.2 9.6 7.5 14.7 43.8 20.3 8.9 7.2 26.7 8.4 14.7 8.9 8.2 17.2 7.2 12.9 8.4 4.1 13.4 14.0 0.0 3.7 0.1 18.4 18.3 7.6 13.7 1.7 31.3 6.5 6.9 15.2 40.2 39.2 1.3 4.4 8.9 11.8 4.6 1.7 39.0 30.1 14.2 5.1 41.2 0.7 7.5 27.7 32.0 21.5 3.9 3.0 9.2 20.1 26.2 7.0 7.7 5.7 121.3 13.0 5.4 2.9 7.7 2.3 0.0 13.4 9.4 3.1 3.6 23.8 18.3 6.7 12.8 3.5 6.8 16.6 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 IGKC HCAK1 ENSG00000211592 "Immunoglobulin kappa constant" 2 88857161-88857683 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 35196.7;lymphoid tissue: 63075.6" "Group enriched" "Detected in many" 12 "B-cells: 72318.1;Plasma cells: 96515.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 21 "memory B-cell: 39143.0;naive B-cell: 35081.5" "Lineage enriched" "Detected in all" 23 "B-cells: 39143.0" "Group enriched" "Detected in many" 6 "Daudi: 9909.1;U-266/70: 10337.6;U-266/84: 3927.9;U-698: 12154.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB015377 Uncertain "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB015377: AB_2251264" "prognostic favorable (6.59e-4)" "unprognostic (1.04e-2)" "unprognostic (3.54e-2)" "unprognostic (1.06e-2)" "unprognostic (8.82e-3)" "prognostic favorable (1.18e-4)" "unprognostic (1.24e-1)" "unprognostic (1.79e-1)" "unprognostic (3.19e-2)" "unprognostic (2.81e-3)" "unprognostic (2.82e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (2.17e-9)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.59e-1)" 1025.4 2379.8 13.1 20500.0 13.3 6315.2 11287.7 11.3 33.6 3649.2 26.7 35196.7 24515.5 877.3 474.1 5708.4 1137.6 5995.3 810.4 11.4 16.7 1176.6 1580.5 5824.2 21356.1 25.1 18.2 2214.9 462.9 72.6 101.8 22.2 15.3 843.6 30618.3 4.0 19606.1 2123.2 32.9 250.8 17061.1 1259.7 43.5 26904.1 22740.5 1083.9 13.4 8576.0 2151.1 8.1 63075.6 24817.5 705.0 20.2 17.1 0.0 0.0 0.0 0.0 0.0 103.7 0.0 0.0 0.1 0.0 0.0 0.0 9909.1 15.3 0.0 1.0 22.2 0.0 0.0 0.0 510.2 0.0 30.9 0.0 0.0 0.0 67.8 29.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.8 0.4 0.0 0.0 18.3 83.2 28.8 0.0 0.0 16.7 56.4 1509.5 0.6 0.0 79.6 146.1 19.6 1.5 6.0 0.5 0.5 17.2 66.7 0.0 56.9 24.3 44.0 10337.6 3927.9 12154.4 0.0 28.9 0.0 47.5 55.6 31.6 24.6 11.2 21.7 39143.0 28.3 18.3 46.6 35081.5 15.2 16.8 65.2 24.1 29.1 1735.4 23.7 8567.0 13.1 13.3 11.3 33.6 11.4 16.7 25.1 18.2 15.3 43.5 13.4 20.2 58.6 336.5 1863.8 0.0 72318.1 0.0 189.2 0.0 2.2 0.0 8.8 7.0 5.7 163.0 88.5 0.0 0.0 48.0 452.1 39.8 3.9 0.0 2.8 0.7 0.3 72.8 77.8 1658.9 0.0 0.2 37.3 186.5 64.7 0.4 849.0 15.5 340.2 334.8 8.9 0.0 0.0 35.1 0.0 496.3 0.0 11.0 0.0 64.4 0.0 0.0 26.4 0.0 59.8 0.0 0.0 0.0 25.9 0.4 96515.7 193.2 0.3 45.2 12.4 0.0 0.0 3.7 38.4 0.3 0.2 5.9 0.0 49.4 6505.3 0.1 50.2 1.9 IGKJ5 ENSG00000211593 "Immunoglobulin kappa joining 5" 2 88860568-88860605 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "intestine: 1221.3;lymphoid tissue: 1365.8;salivary gland: 643.7;stomach 1: 1066.6;urinary bladder: 436.6" "Cell type enriched" "Detected in single" 13 "B-cells: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 24 "memory B-cell: 9254.1;naive B-cell: 8737.5" "Lineage enriched" "Detected in all" 25 "B-cells: 9254.1" "Cell line enriched" "Detected in some" 24 "U-698: 3392.4" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (4.92e-2)" "unprognostic (2.57e-2)" "unprognostic (3.68e-2)" "unprognostic (9.30e-3)" "prognostic favorable (1.83e-4)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (5.49e-6)" "unprognostic (2.00e-2)" "unprognostic (4.25e-1)" "unprognostic (2.02e-1)" 25.2 42.2 0.5 1365.8 0.7 164.5 236.5 0.6 4.5 73.7 0.3 1194.4 1221.3 13.4 5.8 130.7 8.8 78.5 26.1 0.9 0.7 18.0 30.8 157.6 529.7 1.6 0.6 63.3 29.2 6.6 0.0 4.1 1.2 22.8 1171.9 0.0 643.7 17.1 0.0 5.8 1078.7 40.6 4.9 672.7 1066.6 12.4 0.7 61.5 4.3 0.0 1213.5 436.6 0.0 0.9 17.7 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.0 142.3 0.0 0.0 0.0 0.0 0.0 7.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 58.5 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.3 3.5 11.4 3.2 1.9 3392.4 0.0 8.1 0.0 3.3 10.1 10.2 3.8 1.3 2.2 9254.1 18.4 3.5 7.4 8737.5 9.5 3.4 9.4 7.6 3.4 373.6 8.8 1167.3 0.5 0.7 0.6 4.5 0.9 0.7 1.6 0.6 1.2 4.9 0.7 0.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ4 ENSG00000211594 "Immunoglobulin kappa joining 4" 2 88860886-88860922 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3282.9;lymphoid tissue: 2905.5;stomach 1: 2295.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 42 "memory B-cell: 36413.7;naive B-cell: 27723.7" "Lineage enriched" "Detected in all" 48 "B-cells: 36413.7" "Cell line enhanced" "Detected in some" "BEWO: 16.9;Daudi: 23.5;HDLM-2: 58.4;RPMI-8226: 43.3;SH-SY5Y: 27.6;U-698: 25.7" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 80.0 268.7 0.6 2905.5 0.7 407.6 414.6 0.3 4.1 110.0 0.5 1844.1 3282.9 29.5 62.5 433.0 33.3 138.1 34.8 0.6 1.1 48.2 104.6 481.3 932.6 2.9 0.7 117.5 29.3 1.7 0.0 1.3 1.3 56.4 1849.6 0.3 1142.3 54.8 3.9 17.3 2184.0 78.1 2.6 1246.0 2295.9 39.7 1.8 113.5 11.4 0.0 2661.5 645.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 58.4 0.0 0.0 0.0 0.0 0.0 9.1 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 2.0 10.4 0.0 0.0 0.0 0.0 9.1 43.3 0.0 0.0 6.7 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 7.3 8.5 3.3 0.0 25.7 0.0 0.0 0.0 114.4 64.9 20.3 24.9 9.5 16.8 36413.7 15.8 15.2 32.5 27723.7 22.7 16.1 60.0 21.5 25.4 759.9 22.8 3519.3 0.6 0.7 0.3 4.1 0.6 1.1 2.9 0.7 1.3 2.6 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ3 ENSG00000211595 "Immunoglobulin kappa joining 3" 2 88861221-88861258 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 1010.8;lymphoid tissue: 997.2;stomach 1: 710.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 12 "spinal cord: 18.3" "Group enriched" "Detected in all" 26 "memory B-cell: 8663.4;naive B-cell: 7153.9" "Lineage enriched" "Detected in all" 28 "B-cells: 8663.4" "Group enriched" "Detected in some" 6 "HDLM-2: 105.2;RPMI-8226: 89.2;U-698: 41.2" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" 15.1 19.6 0.8 886.7 0.7 115.0 111.2 0.3 1.3 19.2 0.5 587.3 1010.8 7.6 0.0 68.8 7.9 44.8 9.3 0.9 0.6 14.3 41.1 101.9 490.2 1.2 0.5 31.1 0.0 0.0 0.0 1.9 1.5 18.2 546.6 0.6 362.3 12.6 8.7 2.5 726.3 19.9 18.3 548.6 710.1 9.7 0.9 53.9 5.1 3.9 997.2 236.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 105.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 89.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 0.0 0.0 41.2 0.0 0.0 0.0 17.0 8.6 57.9 1.9 1.1 9.2 8663.4 3.0 3.3 5.9 7153.9 5.7 5.1 61.8 7.1 15.2 309.9 7.8 660.0 0.8 0.7 0.3 1.3 0.9 0.6 1.2 0.5 1.5 18.3 0.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKJ2 J2 ENSG00000211596 "Immunoglobulin kappa joining 2" 2 88861525-88861563 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 2670.6;lymphoid tissue: 2226.1;salivary gland: 1187.7;stomach 1: 1719.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 22200.6;naive B-cell: 20663.6" "Lineage enriched" "Detected in all" 52 "B-cells: 22200.6" "Group enriched" "Detected in many" 7 "HDLM-2: 213.9;RPMI-8226: 179.1" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" 67.9 154.0 0.6 1862.6 0.9 296.5 312.9 0.1 4.0 158.7 0.7 1762.7 2670.6 37.5 0.0 308.3 14.3 114.1 19.6 0.6 0.6 27.0 61.7 236.7 693.3 4.3 1.4 71.6 72.5 1.9 0.0 1.1 1.2 46.0 1364.3 0.0 1187.7 20.2 2.9 5.2 1974.3 28.2 1.5 1097.1 1719.7 44.8 0.9 73.5 5.1 0.0 2226.1 494.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.1 0.0 0.0 3.5 0.0 0.0 0.0 213.9 0.0 9.7 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 8.0 3.6 0.0 0.0 7.4 2.5 179.1 0.0 0.0 3.2 17.5 4.8 0.0 0.0 0.0 0.0 29.6 10.7 0.0 3.4 3.7 7.6 5.3 0.0 29.0 0.0 1.8 0.0 19.7 33.6 12.8 10.3 7.7 12.8 22200.6 15.0 8.1 23.3 20663.6 9.5 9.6 42.6 10.8 18.6 430.3 17.4 2451.2 0.6 0.9 0.1 4.0 0.6 0.6 4.3 1.4 1.2 1.5 0.9 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKJ1 J1 ENSG00000211597 "Immunoglobulin kappa joining 1" A0A0A0MT89 2 88861886-88861923 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 3082.3;lymphoid tissue: 3301.5;salivary gland: 1202.6;stomach 1: 2816.8;urinary bladder: 1106.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 418 "memory B-cell: 38345.4;naive B-cell: 32121.1;plasmacytoid DC: 14778.6" "Group enriched" "Detected in all" 390 "B-cells: 38345.4;dendritic cells: 14778.6" "Cell line enriched" "Detected in many" 4 "U-266/70: 21925.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" 70.6 227.2 1.9 3301.5 1.5 424.8 363.1 1.3 9.2 71.7 5.0 1960.8 3082.3 41.6 0.0 278.0 18.1 157.4 31.0 3.2 2.2 31.7 92.0 382.5 839.3 3.4 2.4 127.7 50.3 2.0 0.0 6.3 2.9 50.4 1743.7 0.2 1202.6 16.4 6.9 8.8 2231.5 61.2 3.4 1516.0 2816.8 31.2 2.1 115.3 6.2 0.0 2770.1 1106.5 0.0 2.9 22.9 0.0 0.0 0.0 0.0 0.0 62.7 0.0 0.0 0.0 0.0 7.4 0.0 9.9 2.5 0.0 0.0 14.6 0.0 0.0 0.0 851.1 0.0 10.1 0.0 0.0 0.0 34.5 21.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 10.3 12.1 11.8 0.0 0.0 23.1 0.0 4365.8 0.0 0.0 10.3 18.7 0.0 0.0 4.9 0.0 0.0 31.0 0.0 0.0 9.7 2.4 34.6 21925.7 5461.9 93.7 0.0 6.3 0.0 48.3 44.8 22.7 19.1 17.9 25.4 38345.4 27.2 13.8 57.2 32121.1 20.1 20.9 68.0 38.9 26.9 14778.6 29.9 3897.0 1.9 1.5 1.3 9.2 3.2 2.2 3.4 2.4 2.9 3.4 2.1 2.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV4-1 "B3, IGKV41" ENSG00000211598 "Immunoglobulin kappa variable 4-1" P06312 2 88885397-88886153 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1805.7;lymphoid tissue: 3169.0" "Cell type enriched" "Detected in some" 219 "Plasma cells: 46306.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 588 "memory B-cell: 3036.3;naive B-cell: 3070.9" "Lineage enriched" "Detected in all" 591 "B-cells: 3070.9" "Cell line enhanced" "Detected in some" "Daudi: 14.9;RPMI-8226: 10.4;SH-SY5Y: 6.9;U-266/70: 7.5" "Immunoglobulin genes" NA NA 8500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.41e-5)" "unprognostic (9.19e-2)" "unprognostic (4.29e-3)" "unprognostic (5.42e-3)" "unprognostic (2.08e-2)" "prognostic favorable (8.25e-4)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (3.32e-1)" "unprognostic (3.71e-3)" "unprognostic (1.56e-1)" "unprognostic (3.29e-1)" "prognostic unfavorable (2.52e-6)" "unprognostic (1.99e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" "unprognostic (1.19e-1)" 55.9 296.3 0.4 1054.1 0.9 342.1 665.2 0.4 3.4 145.2 2.4 1805.7 1769.7 46.8 19.4 195.7 41.3 188.2 51.9 0.4 1.2 35.0 76.1 302.3 816.8 1.9 0.8 86.5 28.3 2.5 2.8 1.0 3.5 43.9 1318.2 0.1 701.8 89.6 1.0 8.6 1023.0 66.4 3.6 972.3 1125.7 125.7 0.7 405.1 51.0 0.1 3169.0 758.2 19.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.9 0.0 1.7 0.0 0.0 0.0 3.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.6 3.6 0.3 0.0 0.0 1.4 2.2 10.4 0.0 0.0 4.0 6.9 2.3 0.0 0.0 0.0 0.0 0.7 2.6 0.0 0.8 1.1 1.0 7.5 0.2 0.8 0.0 1.2 0.0 3.9 3.2 5.1 1.6 0.9 1.7 3036.3 1.9 1.1 2.8 3070.9 2.1 1.3 2.4 1.6 2.4 2.3 1.7 344.9 0.4 0.9 0.4 3.4 0.4 1.2 1.9 0.8 3.5 3.6 0.7 1.5 0.0 0.0 0.0 0.0 210.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 17.0 40.2 0.0 0.0 0.0 2.2 2.8 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 46306.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 15.7 0.0 0.1 0.0 IGKV5-2 "B2, IGKV52" ENSG00000211599 "Immunoglobulin kappa variable 5-2" P06315 2 88897232-88897784 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9;lymphoid tissue: 83.1" "Cell type enriched" "Detected in some" 193 "Plasma cells: 1664.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "memory B-cell: 21.4;naive B-cell: 17.2" "Lineage enriched" "Detected in many" 21 "B-cells: 21.4" "Group enriched" "Detected in some" 19 "Daudi: 4.2;HDLM-2: 1.8;RPMI-8226: 2.3" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 4700000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.77e-3)" "unprognostic (1.26e-2)" "unprognostic (1.34e-1)" "unprognostic (2.49e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.37e-1)" "unprognostic (2.26e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (8.62e-6)" "unprognostic (2.60e-1)" "unprognostic (2.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.85e-2)" 0.9 0.0 0.0 10.3 0.0 6.4 19.6 0.0 0.0 5.3 0.0 23.3 35.9 0.8 0.0 4.0 0.9 0.9 0.1 0.0 0.0 0.9 1.0 6.3 17.3 0.0 0.0 0.4 0.4 0.5 0.0 0.0 0.0 0.6 11.1 0.0 14.9 1.9 0.0 0.5 14.3 0.2 0.0 23.5 15.3 0.0 0.0 3.0 1.0 0.0 83.1 4.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 17.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1664.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 IGKV1-5 ENSG00000243466 "Immunoglobulin kappa variable 1-5" P01602 2 88947301-88947957 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 777.1;lymphoid tissue: 1459.2;urinary bladder: 945.2" "Cell type enriched" "Detected in some" 240 "Plasma cells: 39194.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 364 "memory B-cell: 859.0;naive B-cell: 860.5" "Lineage enriched" "Detected in many" 364 "B-cells: 860.5" "Cell line enhanced" "Detected in some" "Daudi: 4.0;HL-60: 2.4;RPMI-8226: 5.0;SCLC-21H: 2.9;SH-SY5Y: 4.5" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.19e-4)" "unprognostic (1.26e-2)" "unprognostic (3.12e-3)" "unprognostic (5.00e-3)" "unprognostic (1.59e-2)" "prognostic favorable (3.47e-4)" "unprognostic (7.60e-2)" "unprognostic (2.84e-1)" "unprognostic (1.68e-1)" "unprognostic (3.32e-2)" "unprognostic (2.28e-1)" "unprognostic (3.58e-1)" "prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (8.27e-2)" "unprognostic (3.17e-2)" 35.8 82.0 0.2 639.7 0.2 115.4 233.9 0.1 1.6 115.8 0.6 777.1 528.7 17.1 2.0 146.2 86.9 124.8 18.7 0.1 0.5 36.2 32.0 125.3 387.2 1.0 0.2 60.8 10.8 0.5 3.0 0.4 0.3 16.7 745.0 0.0 392.2 34.8 0.9 3.2 429.7 24.4 1.3 915.4 456.3 11.5 0.2 155.3 58.4 0.0 1459.2 945.2 28.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.4 1.6 0.5 0.0 0.0 0.3 1.0 5.0 0.0 0.0 2.9 4.5 0.2 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.4 0.7 0.4 0.6 0.1 0.4 0.0 0.6 0.0 0.7 1.2 1.3 0.5 0.2 0.4 859.0 2.3 0.3 1.0 860.5 0.2 0.3 1.4 0.4 0.6 0.7 0.6 113.5 0.2 0.2 0.1 1.6 0.1 0.5 1.0 0.2 0.3 1.3 0.2 0.5 0.0 0.0 0.6 0.0 163.2 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.0 0.0 0.0 7.0 89.7 0.0 0.0 0.0 0.7 3.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39194.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 11.8 0.0 0.2 0.0 IGKV1-6 ENSG00000239855 "Immunoglobulin kappa variable 1-6" A0A0C4DH72 2 88966262-88966767 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 155.5;lymphoid tissue: 606.3" "Cell type enriched" "Detected in some" 33 "Plasma cells: 877.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 801 "memory B-cell: 123.6;naive B-cell: 85.7" "Lineage enriched" "Detected in single" 946 "B-cells: 123.6" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.44e-5)" "unprognostic (5.25e-3)" "unprognostic (3.78e-2)" "unprognostic (8.68e-3)" "unprognostic (3.23e-2)" "prognostic favorable (1.81e-4)" "unprognostic (3.86e-3)" "unprognostic (3.86e-2)" "unprognostic (3.00e-2)" "unprognostic (5.80e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (5.23e-3)" "unprognostic (3.02e-1)" "unprognostic (2.54e-1)" "unprognostic (2.54e-1)" 8.2 1.7 0.1 84.1 0.1 37.0 50.3 0.0 0.4 16.5 0.1 155.5 110.5 4.0 4.1 23.5 5.0 18.1 5.3 0.0 0.0 7.7 6.3 20.0 82.3 0.1 0.1 4.0 1.8 0.0 1.1 0.0 0.0 4.3 145.9 0.0 95.0 2.2 0.2 0.6 59.1 5.1 0.2 209.5 130.3 0.7 0.0 22.7 16.4 0.0 606.3 144.8 8.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 123.6 0.0 0.0 0.1 85.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.1 0.1 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 877.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 IGKV3-7 ENSG00000243063 "Immunoglobulin kappa variable 3-7 (non-functional)" A0A075B6H7 2 88978468-88979081 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 18.6;lymphoid tissue: 22.2;salivary gland: 15.9;stomach 1: 10.2" "Group enriched" "Detected in some" 37 "B-cells: 1.5;Plasma cells: 5.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 27.8;naive B-cell: 24.3" "Lineage enriched" "Detected in single" 65 "B-cells: 27.8" "Not detected" "Not detected" HPA047702 Approved "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.17e-4)" "unprognostic (3.07e-3)" "unprognostic (3.96e-2)" "unprognostic (1.28e-2)" "unprognostic (1.20e-3)" "unprognostic (1.19e-1)" "unprognostic (5.91e-2)" "unprognostic (2.73e-1)" "unprognostic (4.24e-2)" "unprognostic (2.15e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" 0.3 0.4 0.0 15.0 0.0 4.2 3.9 0.0 0.0 2.1 0.0 18.6 15.1 0.3 0.1 1.5 0.1 1.3 0.0 0.0 0.0 0.2 0.5 1.8 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.4 13.6 0.0 15.9 0.1 0.0 0.0 11.2 0.7 0.0 4.9 10.2 0.0 0.0 1.4 0.1 0.0 22.2 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.8 0.0 0.0 0.0 24.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-8 "IGKV18, L9" ENSG00000240671 "Immunoglobulin kappa variable 1-8" A0A0C4DH67 2 88992409-88992931 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 29.7;lymphoid tissue: 55.0;salivary gland: 21.2;stomach 1: 18.6;urinary bladder: 41.7" "Cell type enriched" "Detected in some" 40 "Plasma cells: 622.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 311 "memory B-cell: 131.0;naive B-cell: 136.4" "Lineage enriched" "Detected in single" 317 "B-cells: 136.4" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 6100000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.64e-4)" "unprognostic (1.56e-2)" "unprognostic (8.07e-2)" "unprognostic (6.41e-3)" "prognostic favorable (5.13e-4)" "unprognostic (6.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-2)" "unprognostic (1.75e-1)" "unprognostic (7.79e-2)" "prognostic unfavorable (4.14e-7)" "unprognostic (6.94e-2)" "unprognostic (1.34e-1)" "unprognostic (4.22e-2)" "unprognostic (2.98e-1)" 2.1 2.5 0.0 13.5 0.0 7.1 6.7 0.0 0.1 2.0 0.0 29.7 12.0 1.3 0.0 2.9 1.4 5.4 1.5 0.0 0.0 3.3 2.1 4.8 13.7 0.0 0.0 0.5 0.9 0.0 0.1 0.0 0.0 1.4 19.3 0.0 21.2 0.7 0.0 0.1 13.9 0.6 0.0 51.3 18.6 0.3 0.0 7.0 3.3 0.0 55.0 41.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 131.0 0.0 0.4 0.1 136.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 622.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1-9 "IGKV19, L8" ENSG00000241755 "Immunoglobulin kappa variable 1-9" A0A0C4DH69 2 89009982-89010515 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 428.1;lymphoid tissue: 671.3;stomach 1: 283.7" "Cell type enriched" "Detected in some" 116 "Plasma cells: 7178.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 705 "memory B-cell: 300.5;naive B-cell: 296.8" "Lineage enriched" "Detected in single" 709 "B-cells: 300.5" "Cell line enhanced" "Detected in some" "HL-60: 1.2;NB-4: 1.0;RPMI-8226: 2.9;TIME: 1.2" HPA048721 Approved "Immunoglobulin genes" NA NA 4500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.10e-7)" "unprognostic (1.30e-2)" "unprognostic (1.95e-2)" "unprognostic (2.55e-3)" "unprognostic (4.70e-2)" "prognostic favorable (4.91e-4)" "unprognostic (3.30e-2)" "unprognostic (1.57e-1)" "unprognostic (1.09e-2)" "unprognostic (6.80e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.04e-8)" "unprognostic (4.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (3.40e-1)" 12.6 12.6 0.2 184.3 0.4 53.6 202.8 0.0 1.3 15.8 0.4 428.1 267.0 8.3 0.8 52.9 78.3 30.0 13.9 0.1 0.1 15.4 17.9 40.1 201.8 0.3 0.1 20.7 2.5 0.5 1.3 0.1 0.2 12.8 348.6 0.0 221.3 13.3 0.5 1.6 182.8 13.3 0.4 313.1 283.7 35.1 0.1 85.1 34.2 0.0 671.3 187.5 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 1.0 0.3 0.0 0.0 0.0 0.9 2.9 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.1 0.0 0.5 0.0 0.2 0.0 0.2 0.0 0.2 0.4 0.1 0.2 0.0 0.1 300.5 0.1 0.0 0.3 296.8 0.0 0.1 0.3 0.2 0.2 0.1 0.3 34.5 0.2 0.4 0.0 1.3 0.1 0.1 0.3 0.1 0.2 0.4 0.1 0.3 0.0 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 10.7 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7178.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 IGKV3-11 ENSG00000241351 "Immunoglobulin kappa variable 3-11" P04433 2 89027171-89027731 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1373.3;lymphoid tissue: 2812.9;urinary bladder: 1822.6" "Cell type enriched" "Detected in some" 129 "Plasma cells: 27475.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 9 "spinal cord: 19.8" "Group enriched" "Detected in many" 292 "memory B-cell: 1729.8;naive B-cell: 1401.2" "Lineage enriched" "Detected in many" 323 "B-cells: 1729.8" "Cell line enhanced" "Detected in some" "BEWO: 3.0;Daudi: 2.0;SCLC-21H: 3.7;SH-SY5Y: 4.6" HPA047702 Approved "Immunoglobulin genes" NA NA 18000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (3.97e-3)" "unprognostic (1.17e-2)" "unprognostic (3.51e-2)" "unprognostic (1.91e-2)" "unprognostic (2.70e-2)" "prognostic favorable (1.36e-5)" "unprognostic (2.02e-1)" "unprognostic (3.20e-1)" "unprognostic (5.73e-2)" "unprognostic (2.86e-2)" "unprognostic (1.70e-1)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.26e-8)" "unprognostic (5.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" 45.8 60.5 0.4 733.2 0.3 189.1 385.3 0.2 2.1 136.2 0.6 1373.3 701.6 32.1 11.5 143.5 34.0 253.5 18.9 0.2 0.6 44.4 55.2 227.4 575.7 0.6 0.7 120.8 13.7 1.9 3.2 0.9 0.9 30.1 1090.9 0.1 496.0 60.9 1.2 14.2 536.0 59.5 19.8 1100.0 788.6 22.2 0.3 261.9 88.8 0.9 2812.9 1822.6 33.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.4 1.8 1.5 0.0 0.0 3.7 4.6 0.4 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.7 0.7 0.6 1.8 0.3 0.1 0.0 1.4 0.0 1.9 1.3 1.2 2.0 0.2 0.7 1729.8 0.8 0.6 1.6 1401.2 0.8 0.8 5.3 0.9 1.1 1.2 1.3 186.7 0.4 0.3 0.2 2.1 0.2 0.6 0.6 0.7 0.9 19.8 0.3 1.0 0.0 0.0 0.5 0.0 211.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 82.6 0.0 0.0 0.0 2.5 1.9 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.7 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27475.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.0 62.0 0.0 0.3 0.0 IGKV1-12 "IGKV112, L19" ENSG00000243290 "Immunoglobulin kappa variable 1-12" A0A0C4DH73 2 89040224-89040745 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 395.8;lymphoid tissue: 788.8" "Cell type enriched" "Detected in some" 92 "Plasma cells: 12442.9" "Cancer enhanced" "Detected in many" "stomach cancer: 17.2" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 820 "memory B-cell: 259.8;naive B-cell: 164.2" "Lineage enriched" "Detected in single" 1005 "B-cells: 259.8" "Cell line enhanced" "Detected in some" "BEWO: 1.5;Daudi: 2.1;RPMI-8226: 1.9;SH-SY5Y: 1.9" HPA048721 Approved "Immunoglobulin genes" NA NA 13000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (6.09e-4)" "prognostic favorable (1.59e-4)" "unprognostic (7.33e-2)" "unprognostic (3.74e-2)" "prognostic favorable (3.85e-5)" "unprognostic (5.89e-2)" "unprognostic (5.74e-1)" "unprognostic (7.13e-2)" "unprognostic (6.15e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (6.59e-8)" "unprognostic (1.18e-1)" "unprognostic (1.84e-1)" "unprognostic (2.68e-1)" "unprognostic (1.71e-1)" 13.6 144.8 0.0 201.7 0.2 73.1 116.8 0.0 0.4 50.8 0.2 395.8 240.6 7.3 0.0 57.1 16.2 69.6 9.9 0.1 0.1 13.7 17.8 65.3 238.6 0.6 0.0 18.1 7.2 0.2 1.4 0.0 1.1 7.2 278.6 0.0 219.0 5.4 0.4 2.8 231.2 11.2 1.2 360.5 254.9 6.7 0.0 69.5 32.7 0.0 788.8 243.3 9.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.0 259.8 0.0 0.1 0.1 164.2 0.0 0.1 0.2 0.1 0.1 0.1 0.1 24.3 0.0 0.2 0.0 0.4 0.1 0.1 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 1.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 1.8 1.6 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12442.9 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.0 0.3 5.0 0.0 0.0 0.0 IGKV3-15 ENSG00000244437 "Immunoglobulin kappa variable 3-15" P01624 2 89085177-89085787 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 785.8;lymphoid tissue: 1996.3;urinary bladder: 784.8" "Cell type enriched" "Detected in some" 85 "Plasma cells: 22923.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 561 "memory B-cell: 2243.8;naive B-cell: 1651.4" "Lineage enriched" "Detected in all" 646 "B-cells: 2243.8" "Cell line enhanced" "Detected in some" "Daudi: 1.7;K-562: 1.3;NB-4: 1.9;RH-30: 1.2;RPMI-8226: 2.2;SCLC-21H: 1.4;SH-SY5Y: 2.5" HPA047702 Approved "Immunoglobulin genes" NA NA 7200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.57e-4)" "unprognostic (1.29e-2)" "unprognostic (7.02e-3)" "unprognostic (3.89e-3)" "unprognostic (9.06e-3)" "unprognostic (2.06e-3)" "unprognostic (5.36e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-1)" "unprognostic (5.82e-3)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.15e-7)" "unprognostic (2.00e-1)" "unprognostic (2.54e-1)" "unprognostic (2.07e-1)" "unprognostic (1.17e-1)" 47.9 114.5 0.0 603.8 0.1 131.0 174.3 0.0 1.5 141.8 0.3 785.8 431.4 19.4 34.7 120.0 30.0 144.4 14.8 0.1 0.3 35.2 36.7 184.8 500.9 0.7 0.3 55.4 9.3 2.5 3.0 0.5 0.3 18.3 649.4 0.0 399.3 114.2 1.0 2.7 335.8 29.5 1.5 1020.7 629.8 64.8 0.2 250.2 77.7 0.0 1996.3 784.8 28.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.4 1.9 0.6 0.0 0.0 0.0 1.2 2.2 0.0 0.0 1.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.4 0.7 0.5 0.0 0.0 0.0 1.0 0.0 1.8 3.4 0.8 1.0 0.4 0.8 2243.8 1.0 1.1 1.8 1651.4 1.0 1.1 1.9 1.0 1.3 1.7 1.5 193.1 0.0 0.1 0.0 1.5 0.1 0.3 0.7 0.3 0.3 1.5 0.2 1.0 0.0 0.0 0.0 0.0 269.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.6 73.4 0.0 0.0 0.0 1.4 1.1 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 22923.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.5 0.0 0.0 0.2 0.0 0.0 28.2 0.0 0.0 0.0 IGKV1-16 "IGKV116, L1" ENSG00000240864 "Immunoglobulin kappa variable 1-16" P04430 2 89099859-89100361 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 279.7;lymphoid tissue: 597.8;urinary bladder: 260.3" "Cell type enriched" "Detected in some" 559 "Plasma cells: 18463.6" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 523 "memory B-cell: 164.7;naive B-cell: 112.8" "Lineage enriched" "Detected in single" 621 "B-cells: 164.7" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 10000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.63e-4)" "unprognostic (7.81e-2)" "unprognostic (1.43e-3)" "unprognostic (2.61e-2)" "unprognostic (3.22e-2)" "unprognostic (1.12e-3)" "unprognostic (1.69e-2)" "unprognostic (1.87e-1)" "unprognostic (8.35e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (2.84e-1)" "unprognostic (1.17e-1)" "unprognostic (3.84e-2)" "unprognostic (5.82e-2)" 11.8 4.7 0.1 159.1 0.1 40.0 75.9 0.0 0.8 76.0 0.6 279.7 199.4 6.3 0.5 34.3 6.6 99.0 11.4 0.0 0.1 9.2 14.9 40.5 155.0 0.2 0.0 17.7 2.0 0.1 3.6 0.1 0.1 5.6 235.6 0.0 126.9 30.9 0.8 0.7 143.6 11.8 0.1 315.4 158.9 2.0 0.1 45.7 18.4 0.0 597.8 260.3 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 164.7 0.0 0.0 0.1 112.8 0.0 0.1 0.2 0.0 0.0 0.0 0.0 16.9 0.1 0.1 0.0 0.8 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.6 21.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18463.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 IGKV1-17 "A30, IGKV117" ENSG00000240382 "Immunoglobulin kappa variable 1-17" P01599 2 89117342-89117844 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 375.0;lymphoid tissue: 454.4" "Cell type enriched" "Detected in some" 113 "Plasma cells: 4510.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 425 "memory B-cell: 105.7;naive B-cell: 82.2" "Lineage enriched" "Detected in single" 478 "B-cells: 105.7" "Cell line enhanced" "Detected in some" "Daudi: 1.9;K-562: 1.2;RPMI-8226: 2.0;SH-SY5Y: 1.4" HPA048721 Approved "Immunoglobulin genes" NA NA 8400000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (7.72e-3)" "unprognostic (1.60e-1)" "unprognostic (7.37e-3)" "unprognostic (1.78e-2)" "unprognostic (5.08e-3)" "prognostic favorable (4.11e-4)" "unprognostic (8.04e-2)" "unprognostic (1.00e-1)" "unprognostic (9.59e-2)" "unprognostic (1.76e-2)" "unprognostic (5.06e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (3.44e-7)" "unprognostic (3.12e-3)" "unprognostic (8.83e-2)" "unprognostic (3.80e-1)" "unprognostic (7.28e-2)" 12.8 26.5 0.1 183.7 0.2 27.7 87.1 0.0 0.7 11.9 0.4 358.5 294.8 6.6 4.1 54.7 12.4 55.7 10.9 0.0 0.1 10.3 14.2 36.5 95.7 0.6 0.0 12.4 3.3 1.1 1.0 0.1 0.2 5.5 375.0 0.0 134.3 31.0 1.3 1.2 152.7 4.7 0.1 306.1 159.7 2.4 0.3 45.6 25.8 0.0 454.4 182.6 6.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.8 2.0 0.0 0.0 0.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 105.7 0.0 0.0 0.1 82.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 12.6 0.1 0.2 0.0 0.7 0.0 0.1 0.6 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4510.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 IGKV3-20 ENSG00000239951 "Immunoglobulin kappa variable 3-20" P01619 2 89142574-89143160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3080.6;lymphoid tissue: 5246.5" "Cell type enriched" "Detected in some" 138 "Plasma cells: 52154.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 329 "memory B-cell: 1602.7;naive B-cell: 1222.4" "Lineage enriched" "Detected in many" 373 "B-cells: 1602.7" "Group enriched" "Detected in many" 215 "U-266/70: 3769.9;U-266/84: 1732.3" HPA047702 Approved "Immunoglobulin genes" NA NA 20000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (1.86e-4)" "unprognostic (4.16e-2)" "unprognostic (1.64e-2)" "unprognostic (1.97e-2)" "unprognostic (1.13e-1)" "prognostic favorable (9.01e-4)" "unprognostic (1.43e-1)" "unprognostic (3.43e-1)" "unprognostic (1.37e-1)" "unprognostic (3.93e-3)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.07e-6)" "unprognostic (7.35e-2)" "unprognostic (5.08e-1)" "unprognostic (6.64e-2)" "unprognostic (2.70e-2)" 104.8 56.4 0.9 1791.2 0.9 380.3 736.4 0.5 4.2 326.9 2.6 3080.6 1714.2 59.0 7.8 302.1 105.2 637.2 55.7 0.5 1.6 106.2 113.5 454.0 2815.6 2.1 8.4 153.5 32.8 5.8 9.6 1.8 1.4 56.1 2731.8 0.2 1270.5 224.5 3.3 13.4 1355.8 82.8 10.4 2699.1 1412.9 24.7 1.2 671.5 224.3 1.8 5246.5 1644.0 70.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.5 0.0 2.1 0.0 0.0 0.0 6.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 2.0 5.9 2.8 0.0 0.0 3.0 6.0 10.4 0.0 0.0 7.7 12.8 1.4 0.0 0.1 0.0 0.0 0.8 4.4 0.0 2.0 1.5 4.3 3769.9 1732.3 1.8 0.0 2.3 0.0 4.0 1.2 0.7 0.7 0.4 0.8 1602.7 0.8 0.6 3.5 1222.4 0.4 0.7 4.2 0.8 1.0 0.9 0.8 196.9 0.9 0.9 0.5 4.2 0.5 1.6 2.1 8.4 1.4 10.4 1.2 1.5 0.1 3.2 1.3 0.0 376.9 0.0 0.0 0.0 5.2 0.0 0.1 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 9.4 0.0 0.0 0.0 55.3 124.4 0.0 1.3 0.0 3.6 5.0 0.1 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 52154.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.0 0.0 0.0 26.7 0.0 0.2 0.0 IGKV6-21 "A26, IGKV621" ENSG00000211611 "Immunoglobulin kappa variable 6-21 (non-functional)" A0A0C4DH24 2 89159751-89160366 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 97.3;lymphoid tissue: 141.0" "Cell type enriched" "Detected in some" 142 "Plasma cells: 1715.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 194 "memory B-cell: 28.8;naive B-cell: 9.8" "Lineage enriched" "Detected in single" 289 "B-cells: 28.8" "Cell line enriched" "Detected in some" 6 "U-266/70: 10.5" "Immunoglobulin genes" NA NA 250000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.82e-4)" "unprognostic (1.80e-2)" "unprognostic (4.99e-3)" "unprognostic (2.32e-2)" "unprognostic (1.51e-3)" "unprognostic (1.93e-1)" "unprognostic (6.32e-2)" "unprognostic (4.74e-2)" "unprognostic (8.91e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" 2.2 0.4 0.0 41.6 0.0 12.0 37.4 0.0 0.1 3.3 0.0 97.3 38.8 1.8 0.6 8.4 1.9 5.9 0.5 0.0 0.0 2.7 2.6 11.9 64.4 0.2 0.0 2.1 0.8 0.0 0.1 0.0 0.0 1.5 79.3 0.0 43.5 9.0 0.0 0.5 38.5 5.0 0.1 63.8 36.3 0.9 0.0 10.2 3.5 0.0 141.0 37.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1715.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV2-24 ENSG00000241294 "Immunoglobulin kappa variable 2-24" A0A0C4DH68 2 89176328-89177160 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 272.7;lymphoid tissue: 474.9;urinary bladder: 935.2" "Cell type enriched" "Detected in some" 252 "Plasma cells: 5620.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "memory B-cell: 48.1" "Lineage enriched" "Detected in single" 482 "B-cells: 48.1" "Cell line enhanced" "Detected in single" "NB-4: 1.3" "Immunoglobulin genes" NA NA 840000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.74e-6)" "unprognostic (4.92e-3)" "unprognostic (1.04e-2)" "unprognostic (2.38e-2)" "unprognostic (3.79e-3)" "prognostic favorable (1.59e-4)" "unprognostic (5.02e-2)" "unprognostic (1.65e-1)" "unprognostic (2.71e-2)" "unprognostic (1.31e-1)" "unprognostic (4.10e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.82e-5)" "unprognostic (1.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" 13.7 14.6 0.1 65.8 0.1 27.4 91.8 0.0 0.6 11.5 0.4 272.7 250.8 3.2 1.1 82.0 6.6 24.1 14.7 0.2 1.0 7.8 8.6 30.0 131.7 0.6 0.1 6.3 5.6 0.2 0.9 0.2 0.9 5.4 180.6 0.0 219.3 3.3 0.3 3.3 98.5 7.9 1.1 474.9 106.8 1.2 0.2 23.7 11.1 0.0 235.6 935.2 14.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.1 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.1 0.0 0.6 0.2 1.0 0.6 0.1 0.9 1.1 0.2 0.3 0.0 0.0 0.0 0.0 22.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5620.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGKV1-27 "A20, IGKV127" ENSG00000244575 "Immunoglobulin kappa variable 1-27" A0A075B6S5 2 89213423-89213928 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0;lymphoid tissue: 347.1;salivary gland: 177.6" "Cell type enriched" "Detected in some" 126 "Plasma cells: 4951.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 683 "memory B-cell: 152.7;naive B-cell: 185.3" "Lineage enriched" "Detected in single" 748 "B-cells: 185.3" "Cell line enhanced" "Detected in single" "BEWO: 1.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 8300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.56e-5)" "unprognostic (6.50e-3)" "unprognostic (2.65e-2)" "unprognostic (1.68e-3)" "unprognostic (1.72e-2)" "prognostic favorable (8.14e-4)" "unprognostic (9.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.41e-1)" "unprognostic (6.99e-3)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (8.84e-5)" "unprognostic (3.23e-2)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-2)" 17.2 9.2 0.0 133.5 0.0 28.5 70.0 0.0 0.4 16.8 0.1 268.0 183.3 6.2 7.7 30.4 6.9 37.5 10.7 0.1 0.1 11.8 9.7 55.2 124.7 0.7 0.3 8.8 4.9 0.2 1.0 0.0 0.1 6.4 212.3 0.0 177.6 8.8 0.6 0.9 200.2 5.1 0.2 276.9 91.9 1.0 0.0 46.9 19.4 0.0 347.1 87.7 6.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 152.7 0.1 0.1 0.1 185.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 15.8 0.0 0.0 0.0 0.4 0.1 0.1 0.7 0.3 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 39.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.3 12.2 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4951.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 IGKV2-28 ENSG00000244116 "Immunoglobulin kappa variable 2-28" A0A075B6P5 2 89221698-89222461 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1044.6;lymphoid tissue: 1735.3" "Cell type enriched" "Detected in some" 92 "Plasma cells: 1868.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 11.1" "Lineage enriched" "Detected in single" 13 "B-cells: 11.1" "Cell line enhanced" "Detected in some" "BEWO: 2.4;Daudi: 2.8;HL-60: 3.6;K-562: 2.0;NB-4: 2.7;RPMI-8226: 4.5;SCLC-21H: 2.1;SH-SY5Y: 1.7" "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.03e-2)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.32e-4)" "unprognostic (2.12e-2)" "unprognostic (6.32e-3)" "unprognostic (3.14e-1)" "unprognostic (3.71e-2)" "unprognostic (5.21e-2)" "unprognostic (2.64e-2)" 36.2 40.2 0.2 402.4 0.2 180.2 425.2 0.1 1.1 56.6 0.9 1044.6 756.7 38.2 4.9 662.7 29.0 130.8 22.3 0.1 0.3 46.2 40.2 157.6 584.6 0.6 0.9 87.9 19.5 3.8 3.3 0.5 0.3 21.1 709.6 0.1 732.4 95.0 1.8 7.1 425.6 23.9 0.8 1207.7 530.0 161.9 0.2 167.6 84.8 0.0 1735.3 494.1 30.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 1.1 4.5 0.0 0.4 2.1 1.7 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.9 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.4 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.2 11.1 0.2 0.1 0.8 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.1 1.1 0.1 0.3 0.6 0.9 0.3 0.8 0.2 0.9 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1868.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 20.3 0.0 0.0 0.0 IGKV2-30 ENSG00000243238 "Immunoglobulin kappa variable 2-30" P06310 2 89244781-89245596 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 631.0;lymphoid tissue: 670.2;stomach 1: 323.1" "Cell type enriched" "Detected in some" 365 "Plasma cells: 25365.6" "Cancer enhanced" "Detected in many" "stomach cancer: 26.0" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 316 "memory B-cell: 561.0;naive B-cell: 325.4" "Lineage enriched" "Detected in many" 400 "B-cells: 561.0" "Cell line enriched" "Detected in some" 388 "U-698: 8426.0" "Immunoglobulin genes" NA NA 6800000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.84e-5)" "unprognostic (1.26e-2)" "unprognostic (2.88e-2)" "unprognostic (1.41e-1)" "prognostic favorable (6.78e-5)" "unprognostic (6.92e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-2)" "unprognostic (9.82e-3)" "unprognostic (1.84e-1)" "unprognostic (3.07e-1)" "prognostic unfavorable (4.53e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.53e-1)" "unprognostic (3.50e-1)" 15.0 9.4 0.1 160.7 0.2 75.9 237.0 0.1 1.3 19.6 0.7 631.0 394.3 5.6 0.8 37.8 11.5 35.0 17.9 0.1 0.1 15.1 29.6 67.3 176.7 1.4 0.1 15.8 7.8 0.1 2.3 0.2 0.2 7.8 324.5 0.0 220.5 23.3 0.6 2.0 260.2 19.1 0.6 670.2 323.1 21.2 0.1 40.9 18.8 0.0 600.3 207.5 21.5 1.1 5.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 13.1 4.6 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.1 2.7 1.9 0.0 0.4 0.0 0.9 3.8 0.0 2.6 0.0 0.0 5.6 0.0 0.0 21.7 0.1 2.6 0.3 1.7 8426.0 0.0 2.7 0.0 0.5 0.4 0.2 0.2 0.0 0.2 561.0 0.1 0.2 0.4 325.4 0.0 0.2 1.4 0.2 0.3 0.7 0.3 53.3 0.1 0.2 0.1 1.3 0.1 0.1 1.4 0.1 0.2 0.6 0.1 1.1 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 30.5 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25365.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.2 0.0 0.3 0.0 IGKV1-33 "IGKV133, O18" ENSG00000242076 "Immunoglobulin kappa variable 1-33" P01594 2 89266494-89268506 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1727.5;stomach 1: 627.3;urinary bladder: 623.3" "Cell type enriched" "Detected in some" 131 "Plasma cells: 2044.1" "Cancer enhanced" "Detected in many" "stomach cancer: 5.5" "Region enriched" "Detected in many" 7 "spinal cord: 12.0" "Group enriched" "Detected in some" 378 "memory B-cell: 369.6;naive B-cell: 441.5" "Lineage enriched" "Detected in many" 411 "B-cells: 441.5" "Cell line enhanced" "Detected in some" "RPMI-8226: 2.7;SCLC-21H: 9.1;SH-SY5Y: 8.8;U-251 MG: 3.5" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.76e-2)" "unprognostic (6.79e-2)" "unprognostic (1.52e-2)" "prognostic favorable (4.58e-5)" "unprognostic (5.06e-2)" "unprognostic (8.55e-3)" "unprognostic (2.31e-1)" "unprognostic (1.63e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-1)" 50.5 21.9 0.1 266.2 0.5 139.5 320.5 0.6 1.0 129.8 0.4 471.5 296.2 20.7 2.8 106.2 33.4 187.2 23.2 0.2 1.6 36.7 37.9 130.4 529.5 0.4 1.0 37.0 8.3 1.9 2.7 0.4 0.7 18.7 511.9 0.2 476.4 127.7 0.7 2.5 175.9 14.5 12.0 820.8 627.3 13.5 0.2 381.9 53.9 0.2 1727.5 623.3 26.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.1 1.9 2.7 0.0 0.0 9.1 8.8 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.4 3.5 0.7 0.0 0.2 0.0 0.6 0.0 0.4 0.3 0.4 0.1 0.0 0.1 369.6 0.2 0.1 0.3 441.5 0.2 0.1 1.0 0.2 0.3 0.3 0.2 39.5 0.1 0.5 0.6 1.0 0.2 1.6 0.4 1.0 0.7 12.0 0.2 1.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2044.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 IGKV1-37 "IGKV137, O14" ENSG00000239862 "Immunoglobulin kappa variable 1-37 (non-functional)" A0A075B6S9 2 89297264-89297785 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.2;lymphoid tissue: 17.2;urinary bladder: 5.6" "Cell type enriched" "Detected in some" 24 "Plasma cells: 73.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 247 "memory B-cell: 21.2;naive B-cell: 28.2" "Lineage enriched" "Detected in single" 283 "B-cells: 28.2" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (3.47e-1)" "unprognostic (1.17e-1)" 0.1 0.2 0.0 2.9 0.0 0.8 2.4 0.0 0.0 0.5 0.0 4.5 3.1 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.4 1.2 2.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 2.6 0.6 0.0 0.0 2.0 0.2 0.0 3.7 1.5 0.0 0.0 0.9 0.1 0.0 17.2 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1-39 ENSG00000242371 "Immunoglobulin kappa variable 1-39" P01597 2 89319625-89320146 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 108.5;lymphoid tissue: 254.9;salivary gland: 151.2;stomach 1: 83.2" "Cell type enriched" "Detected in some" 151 "Plasma cells: 16225.1" "Cancer enhanced" "Detected in many" "stomach cancer: 13.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 388 "memory B-cell: 1069.8;naive B-cell: 935.1" "Lineage enriched" "Detected in many" 415 "B-cells: 1069.8" "Cell line enriched" "Detected in some" 21 "Daudi: 194.2" HPA048721 Approved "Immunoglobulin genes" NA NA 8000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.76e-4)" "unprognostic (5.10e-3)" "unprognostic (4.71e-2)" "prognostic favorable (1.70e-5)" "unprognostic (2.38e-1)" "unprognostic (7.33e-2)" "unprognostic (1.78e-1)" "unprognostic (6.62e-6)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (4.27e-1)" "unprognostic (2.25e-1)" 10.9 9.1 0.0 54.7 0.1 14.2 17.7 0.0 0.1 21.8 0.0 108.5 70.5 5.7 0.0 11.6 12.5 14.3 1.5 0.2 0.0 10.9 6.8 27.2 36.5 0.0 0.0 1.8 3.2 0.0 0.5 0.0 0.2 4.2 13.3 0.0 151.2 0.9 0.2 1.3 74.4 1.2 0.0 254.9 83.2 0.3 0.0 5.9 31.0 0.0 42.5 17.5 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 194.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 1.8 0.0 9.0 0.0 0.0 0.0 0.9 1.0 0.7 0.3 0.3 0.3 1069.8 0.5 0.4 1.1 935.1 0.3 0.6 2.5 0.4 0.6 1.3 0.8 136.4 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 107.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 10.7 0.0 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16225.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 4.9 0.0 0.3 0.0 IGKV2-40 ENSG00000273962 "Immunoglobulin kappa variable 2-40" A0A087WW87 2 89330110-89330429 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 42.8;urinary bladder: 34.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 15.4;naive B-cell: 7.1" "Lineage enriched" "Detected in single" 66 "B-cells: 15.4" "Cell line enhanced" "Detected in single" "Daudi: 1.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (3.31e-1)" "unprognostic (1.94e-2)" 0.4 0.1 0.0 9.3 0.0 1.1 6.7 0.0 0.1 10.2 0.0 9.7 42.8 0.9 0.0 10.5 15.5 0.1 0.1 0.0 0.0 0.3 1.4 10.9 0.9 0.0 0.0 3.2 0.0 0.0 0.1 0.0 0.0 1.1 7.1 0.0 5.9 2.0 0.0 0.1 6.2 0.0 0.0 17.8 19.6 0.2 0.0 1.9 1.2 0.1 6.2 34.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-40 ENSG00000251039 "Immunoglobulin kappa variable 2D-40" P01614 2 89851791-89852497 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 123.3" "Cell type enriched" "Detected in some" 489 "Plasma cells: 1517.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 30.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 494 "memory B-cell: 134.9;naive B-cell: 96.8" "Lineage enriched" "Detected in single" 575 "B-cells: 134.9" "Cell line enhanced" "Detected in single" "Daudi: 3.7" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.01e-4)" "unprognostic (1.16e-2)" "unprognostic (8.37e-2)" "unprognostic (6.04e-2)" "prognostic favorable (9.78e-7)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (2.32e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (3.59e-2)" "unprognostic (3.02e-1)" "unprognostic (2.91e-1)" "unprognostic (1.25e-1)" 1.7 1.4 0.0 21.0 0.0 14.8 13.5 0.0 0.1 10.0 0.0 16.6 6.9 3.0 0.0 35.6 14.4 7.7 2.0 0.0 0.0 1.0 2.9 19.5 65.7 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.6 21.8 0.0 32.3 21.7 0.0 0.0 31.2 1.6 0.0 44.8 38.6 0.4 0.0 26.3 5.7 0.0 123.3 34.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 134.9 0.0 0.0 0.0 96.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1517.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGKV1D-39 ENSG00000251546 "Immunoglobulin kappa variable 1D-39" P04432 2 89862482-89862981 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2922.1;lymphoid tissue: 6491.8;stomach 1: 2259.8" "Cell type enriched" "Detected in some" 298 "Plasma cells: 7890.2" "Cancer enhanced" "Detected in many" "stomach cancer: 12.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 226 "memory B-cell: 470.5;naive B-cell: 733.0" "Lineage enriched" "Detected in many" 275 "B-cells: 733.0" "Group enriched" "Detected in some" 36 "Daudi: 731.4;U-698: 516.7" HPA048721 Approved "Immunoglobulin genes" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.88e-4)" "unprognostic (4.70e-2)" "unprognostic (2.14e-3)" "prognostic favorable (5.99e-5)" "unprognostic (3.84e-1)" "unprognostic (4.34e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (2.96e-2)" "unprognostic (3.92e-1)" "unprognostic (1.84e-1)" 147.3 181.1 0.6 1609.8 0.8 466.1 990.4 0.5 4.2 369.0 2.1 2922.1 2055.2 80.0 52.5 611.3 132.1 629.8 87.5 0.4 2.0 82.3 171.8 685.1 1968.9 2.6 0.8 214.9 26.5 3.5 5.5 1.3 3.6 80.9 2261.1 0.4 1229.7 148.4 2.3 33.2 1255.9 88.7 4.2 1712.0 2259.8 27.6 1.3 770.5 209.3 0.0 6491.8 1816.1 46.9 2.5 0.3 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 731.4 0.5 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.0 0.0 5.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 2.3 6.6 2.4 0.0 0.0 1.0 2.9 10.3 0.0 0.0 11.1 17.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.8 2.5 0.0 0.1 516.7 0.0 1.6 0.0 0.5 0.4 0.8 0.6 0.2 0.4 470.5 0.3 0.3 0.4 733.0 0.5 0.2 2.6 0.8 0.4 0.4 0.3 47.6 0.6 0.8 0.5 4.2 0.4 2.0 2.6 0.8 3.6 4.2 1.3 2.5 0.0 0.0 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7890.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 14.0 0.0 0.0 0.0 IGKV1D-37 "IGKV1D37, O4" ENSG00000250036 "Immunoglobulin kappa variable 1D-37 (non-functional)" P0DSN7 2 89884740-89885216 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 12.7;stomach 1: 15.0;urinary bladder: 20.1" "Cell type enriched" "Detected in single" 11 "Plasma cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 209 "memory B-cell: 13.6;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 284 "B-cells: 29.1" "Cell line enriched" "Detected in single" 5 "HDLM-2: 2.5" HPA048721 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (2.68e-1)" 0.1 0.0 0.0 4.2 0.0 3.3 2.4 0.0 0.0 0.8 0.0 8.6 12.7 0.1 0.4 2.1 0.2 0.5 0.2 0.4 0.0 0.1 0.4 0.8 4.1 0.0 0.1 0.4 1.2 0.0 0.0 0.1 0.0 0.7 1.0 0.0 7.1 0.0 0.2 0.0 6.0 0.2 0.0 6.5 15.0 0.2 0.0 1.1 0.1 0.0 2.5 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-33 ENSG00000239975 "Immunoglobulin kappa variable 1D-33" P01593 2 89913982-89916052 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;lymphoid tissue: 63.0;salivary gland: 73.3" "Cell type enriched" "Detected in some" 410 "Plasma cells: 5131.4" "Cancer enhanced" "Detected in many" "stomach cancer: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 116 "memory B-cell: 6.3;naive B-cell: 16.8" "Lineage enriched" "Detected in single" 169 "B-cells: 16.8" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 4900000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (5.10e-3)" "unprognostic (2.03e-1)" "unprognostic (2.11e-2)" "unprognostic (2.03e-4)" "unprognostic (7.90e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-2)" 2.8 0.5 0.0 3.8 0.1 2.3 8.3 0.0 0.1 3.6 0.1 32.7 1.3 1.4 0.0 4.6 2.7 2.6 0.2 0.2 0.2 4.0 2.2 17.9 6.8 0.0 0.2 0.4 0.5 0.0 0.1 0.0 0.0 1.6 2.0 0.0 73.3 8.6 0.0 0.5 19.1 0.0 0.5 63.0 21.2 0.1 0.0 4.7 3.3 0.2 9.1 16.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5131.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 IGKV2D-30 ENSG00000239571 "Immunoglobulin kappa variable 2D-30" A0A075B6S6 2 89936859-89937679 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3;lymphoid tissue: 33.5;stomach 1: 22.2" "Cell type enriched" "Detected in some" 222 "Plasma cells: 1314.8" "Cancer enhanced" "Detected in some" "stomach cancer: 2.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 379 "memory B-cell: 124.9;naive B-cell: 164.0" "Lineage enriched" "Detected in single" 430 "B-cells: 164.0" "Cell line enriched" "Detected in some" 6 "U-698: 51.7" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.17e-3)" "unprognostic (6.82e-2)" "unprognostic (1.58e-1)" "unprognostic (2.98e-4)" "unprognostic (5.74e-3)" "unprognostic (3.19e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.55e-1)" 0.4 0.4 0.0 6.4 0.0 4.3 5.9 0.0 0.1 0.8 0.0 15.3 11.8 0.4 0.0 1.0 0.4 0.8 0.8 0.1 0.1 1.4 0.7 2.8 6.7 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.1 0.5 11.2 0.0 13.0 4.6 0.0 1.2 8.5 2.0 0.0 29.3 22.2 0.1 0.0 1.6 0.8 0.0 33.5 5.6 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 51.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 124.9 0.0 0.1 0.1 164.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 19.3 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1314.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 IGKV2D-29 ENSG00000243264 "Immunoglobulin kappa variable 2D-29" A0A075B6S2 2 89947512-89948279 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 252.2;lymphoid tissue: 464.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 184.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Group enriched" "Detected in some" 253 "memory B-cell: 360.5;naive B-cell: 489.4" "Lineage enriched" "Detected in many" 292 "B-cells: 489.4" "Cell line enhanced" "Detected in some" "Daudi: 8.5;HDLM-2: 1.2;TIME: 2.1;U-698: 2.2" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.31e-4)" "unprognostic (2.43e-2)" "unprognostic (1.34e-3)" "unprognostic (1.76e-2)" "prognostic favorable (8.34e-4)" "unprognostic (4.43e-3)" "unprognostic (1.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.47e-2)" "unprognostic (5.09e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (9.46e-2)" "unprognostic (2.20e-1)" "unprognostic (2.61e-1)" "unprognostic (7.80e-2)" 11.3 1.0 0.0 73.7 0.1 29.4 49.4 0.1 1.3 12.6 0.8 252.2 97.0 3.9 0.0 9.5 6.5 14.2 3.8 0.1 0.2 3.6 8.4 41.4 139.4 0.3 0.0 9.8 2.8 0.2 0.3 0.0 0.2 3.6 110.9 0.0 106.8 10.3 0.4 3.0 67.9 2.9 0.4 170.2 126.0 1.0 0.1 38.0 7.8 0.0 464.7 35.1 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.0 2.2 0.0 0.1 0.0 0.3 0.4 0.2 0.1 0.0 0.2 360.5 0.2 0.1 0.6 489.4 0.0 0.1 1.6 0.2 0.4 0.2 0.2 42.2 0.0 0.1 0.1 1.3 0.1 0.2 0.3 0.0 0.2 0.4 0.1 0.2 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 184.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 IGKV2D-28 ENSG00000242534 "Immunoglobulin kappa variable 2D-28" P01615 2 89959979-89960754 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 221.6;lymphoid tissue: 462.7;salivary gland: 259.7" "Cell type enriched" "Detected in some" 98 "Plasma cells: 4332.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 224 "memory B-cell: 3054.0;naive B-cell: 2203.9" "Lineage enriched" "Detected in all" 260 "B-cells: 3054.0" "Cell line enhanced" "Detected in some" "HDLM-2: 5.0;RPMI-8226: 2.0;SCLC-21H: 1.9;SH-SY5Y: 4.3;U-698: 4.4" "Immunoglobulin genes" NA NA 3500000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.88e-3)" "unprognostic (2.68e-2)" "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.17e-1)" "unprognostic (1.13e-1)" "unprognostic (2.66e-1)" 9.9 4.8 0.1 162.1 0.2 23.3 35.2 0.0 1.5 7.6 0.3 203.7 221.6 8.3 1.2 113.5 14.0 26.1 4.8 0.3 0.4 11.5 13.3 40.6 166.6 0.7 0.2 2.8 1.9 0.1 0.9 0.4 0.4 11.1 65.9 0.0 259.7 19.2 0.3 1.4 143.3 8.7 0.2 462.7 186.4 5.7 0.2 40.9 37.8 0.3 192.0 157.9 8.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 1.1 0.0 0.0 0.0 5.0 0.0 1.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 0.0 1.9 4.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.6 1.3 0.0 4.4 0.0 1.1 0.0 11.7 7.8 1.2 1.2 0.5 1.3 3054.0 1.3 0.9 2.0 2203.9 0.2 0.9 2.2 1.0 1.5 1.4 1.3 248.7 0.1 0.2 0.0 1.5 0.3 0.4 0.7 0.2 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4332.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 31.5 0.0 0.1 0.0 IGKV2D-26 ENSG00000211623 "Immunoglobulin kappa variable 2D-26" A0A0A0MRZ7 2 89985922-89986702 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 6.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 245 "memory B-cell: 21.8;naive B-cell: 27.1" "Lineage enriched" "Detected in single" 272 "B-cells: 27.1" "Cell line enriched" "Detected in single" 10 "U-698: 1.0" "Immunoglobulin genes" NA NA 1000000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.11e-1)" "unprognostic (6.09e-2)" 0.0 0.4 0.0 1.5 0.1 0.5 1.0 0.0 0.2 0.1 0.0 4.6 3.5 0.0 0.0 0.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.1 0.0 0.0 0.0 2.8 0.0 0.0 2.3 1.3 0.0 0.0 0.5 0.0 0.0 6.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV2D-24 ENSG00000241566 "Immunoglobulin kappa variable 2D-24 (non-functional)" A0A075B6R9 2 90004797-90005629 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.7;lymphoid tissue: 25.5;urinary bladder: 15.3" "Cell type enriched" "Detected in single" 207 "Plasma cells: 165.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hippocampal formation: 1.8" "Group enriched" "Detected in some" 48 "memory B-cell: 6.7;naive B-cell: 2.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Cell line enriched" "Detected in single" 8 "U-937: 1.0" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.21e-4)" "unprognostic (1.78e-1)" "prognostic favorable (8.07e-4)" "unprognostic (2.09e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (4.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.74e-5)" "unprognostic (7.60e-2)" "unprognostic (1.57e-2)" "unprognostic (3.85e-1)" "unprognostic (3.47e-1)" 0.6 0.8 0.0 4.3 0.0 2.7 6.1 0.0 0.7 0.5 0.0 16.8 19.7 0.1 0.0 1.5 0.4 3.5 0.1 1.8 0.0 0.6 0.5 1.8 6.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 7.2 0.0 9.6 0.5 0.0 0.3 7.0 0.1 0.1 25.0 5.2 0.1 0.1 1.7 0.4 0.0 25.5 15.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 165.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV6D-21 "A10, IGKV6D21" ENSG00000225523 "Immunoglobulin kappa variable 6D-21 (non-functional)" A0A0A0MT36 2 90021567-90022185 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 67.0;lymphoid tissue: 152.7;urinary bladder: 227.3" "Cell type enriched" "Detected in some" 7 "Plasma cells: 234.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 154 "memory B-cell: 14.2;naive B-cell: 16.5" "Lineage enriched" "Detected in single" 166 "B-cells: 16.5" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.95e-4)" "unprognostic (5.47e-3)" "unprognostic (2.85e-3)" "prognostic favorable (5.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (3.45e-7)" "unprognostic (7.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (2.07e-1)" 1.1 0.4 0.0 17.2 0.0 17.2 11.8 0.0 0.1 5.4 0.0 67.0 38.8 1.6 0.0 22.1 0.8 2.7 2.1 0.2 0.0 1.6 2.4 6.3 19.8 0.6 0.0 1.1 1.1 0.0 0.0 0.0 0.1 0.8 31.8 0.0 21.1 17.3 0.0 1.2 37.8 1.0 0.0 45.3 13.4 3.4 0.0 9.1 1.4 0.0 152.7 227.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 234.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV3D-20 ENSG00000211625 "Immunoglobulin kappa variable 3D-20" A0A0C4DH25 2 90038848-90039479 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 131.8;lymphoid tissue: 275.4" "Cell type enriched" "Detected in some" 38 "Plasma cells: 289.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 1042 "memory B-cell: 197.3;naive B-cell: 99.0" "Lineage enriched" "Detected in single" 1388 "B-cells: 197.3" "Cell line enriched" "Detected in some" 4 "U-266/70: 19.5" HPA047702 Approved "Immunoglobulin genes" NA NA 11000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.82e-4)" "unprognostic (4.70e-3)" "unprognostic (3.16e-2)" "unprognostic (8.10e-3)" "unprognostic (2.05e-1)" "unprognostic (2.60e-3)" "unprognostic (3.37e-1)" "unprognostic (1.68e-1)" "unprognostic (5.15e-2)" "unprognostic (2.53e-2)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.56e-6)" "unprognostic (7.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.73e-1)" 4.0 6.3 0.0 81.2 0.0 16.0 32.4 0.0 0.6 12.2 0.1 131.8 55.9 2.7 0.0 15.3 4.2 16.2 6.4 0.0 0.1 3.0 6.4 20.6 73.5 0.2 0.1 7.1 3.3 0.0 0.3 0.1 0.1 3.7 88.1 0.0 64.0 3.3 0.1 2.6 77.7 6.0 0.3 88.4 82.5 1.2 0.0 16.2 5.2 0.0 275.4 38.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 19.5 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 197.3 0.0 0.1 0.1 99.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34.1 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 289.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 IGKV6D-41 ENSG00000211626 "Immunoglobulin kappa variable 6D-41 (non-functional)" A0A0C4DH26 2 90069662-90070238 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.7;intestine: 3.4;lymphoid tissue: 2.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 0.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 40 "memory B-cell: 3.0;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 49 "B-cells: 4.9" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 32000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.64e-2)" "unprognostic (4.43e-1)" 0.0 1.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 4.7 0.0 3.4 0.9 0.0 0.0 0.3 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-17 ENSG00000242766 "Immunoglobulin kappa variable 1D-17" A0A075B6S4 2 90082635-90083291 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;lymphoid tissue: 12.5;salivary gland: 5.7" "Cell type enriched" "Detected in some" 13 "Plasma cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 60 "memory B-cell: 7.7;naive B-cell: 4.1" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 1000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.47e-4)" "unprognostic (4.23e-2)" "unprognostic (2.43e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.68e-4)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-5)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (1.17e-1)" "unprognostic (4.04e-3)" 1.3 0.1 0.1 5.1 0.1 0.9 0.8 0.1 0.2 0.3 0.8 6.8 1.5 0.2 0.0 0.5 0.8 0.6 0.0 0.1 0.1 0.3 0.4 1.5 0.8 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 2.2 0.0 5.7 0.3 0.0 0.4 4.7 0.4 0.1 12.5 2.0 0.0 0.1 0.3 0.5 0.0 4.5 1.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-16 ENSG00000241244 "Immunoglobulin kappa variable 1D-16" P01601 2 90100236-90100738 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 79.1;intestine: 92.0;lymphoid tissue: 165.5" "Cell type enriched" "Detected in some" 249 "Plasma cells: 1994.1" "Cancer enhanced" "Detected in many" "lung cancer: 17.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 327 "memory B-cell: 57.6;naive B-cell: 120.1" "Lineage enriched" "Detected in single" 442 "B-cells: 120.1" "Not detected" "Not detected" HPA048721 Approved "Immunoglobulin genes" NA NA 9000000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.41e-4)" "unprognostic (4.41e-3)" "unprognostic (3.96e-3)" "unprognostic (5.39e-2)" "unprognostic (1.35e-3)" "unprognostic (8.61e-2)" "unprognostic (2.92e-1)" "unprognostic (1.27e-1)" "unprognostic (1.54e-2)" "unprognostic (6.61e-3)" "unprognostic (3.25e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (4.37e-1)" "unprognostic (2.38e-1)" "unprognostic (4.66e-2)" "unprognostic (2.84e-1)" 2.4 0.4 0.0 30.2 0.0 15.0 18.9 0.0 0.4 11.0 0.1 92.0 39.0 1.6 0.0 13.8 2.5 79.1 1.3 0.0 0.0 1.7 3.9 10.0 27.5 0.0 0.0 2.5 0.9 0.6 0.1 0.0 0.1 3.6 50.3 0.0 30.3 0.9 0.0 0.2 34.4 1.0 0.3 56.6 26.7 0.4 0.0 9.9 2.7 0.0 165.5 23.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 57.6 0.0 0.0 0.1 120.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1994.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 IGKV3D-15 ENSG00000224041 "Immunoglobulin kappa variable 3D-15" A0A087WSY6 2 90114838-90115402 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 126.7;lymphoid tissue: 203.0;salivary gland: 54.1;stomach 1: 87.4;urinary bladder: 58.0" "Cell type enriched" "Detected in some" 622 "Plasma cells: 3673.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 191 "memory B-cell: 181.1;naive B-cell: 155.6" "Lineage enriched" "Detected in single" 206 "B-cells: 181.1" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HL-60: 2.6;SiHa: 1.7" HPA047702 Approved "Immunoglobulin genes" NA NA 4800000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.11e-4)" "prognostic favorable (7.46e-4)" "unprognostic (9.16e-3)" "unprognostic (1.74e-1)" "unprognostic (1.90e-3)" "unprognostic (7.20e-2)" "unprognostic (9.19e-2)" "unprognostic (4.93e-1)" "unprognostic (3.42e-2)" "unprognostic (1.41e-1)" "unprognostic (2.97e-1)" "prognostic unfavorable (1.82e-6)" "unprognostic (8.99e-2)" "unprognostic (2.62e-1)" "unprognostic (1.21e-1)" "unprognostic (2.04e-1)" 3.1 4.4 0.1 93.5 0.4 11.1 17.1 0.1 0.5 5.9 0.3 111.6 63.0 1.0 0.0 16.4 5.2 10.1 2.3 0.1 0.2 3.6 2.0 18.0 43.6 0.4 0.2 17.9 4.0 0.3 0.1 0.0 0.2 1.7 126.7 0.0 54.1 1.1 0.1 0.6 46.7 4.3 0.3 56.3 87.4 0.2 0.1 13.0 4.5 0.0 203.0 58.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.6 0.0 0.6 0.0 0.1 0.8 0.0 0.0 0.0 0.0 181.1 0.0 0.0 0.1 155.6 0.0 0.0 0.0 0.1 0.1 0.0 0.1 27.5 0.1 0.4 0.1 0.5 0.1 0.2 0.4 0.2 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3673.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGKV1D-13 ENSG00000276566 "Immunoglobulin kappa variable 1D-13" "A0A0B4J2D9, P0DP09" 2 90154073-90154574 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 103.7;lymphoid tissue: 317.6" "Cell type enriched" "Detected in some" 141 "Plasma cells: 6195.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 733 "memory B-cell: 480.8;naive B-cell: 331.6" "Lineage enriched" "Detected in single" 868 "B-cells: 480.8" "Cell line enhanced" "Detected in single" "Daudi: 1.0" HPA048721 Approved "Immunoglobulin genes" NA NA 370000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (4.68e-6)" "unprognostic (4.10e-2)" "unprognostic (2.16e-1)" "unprognostic (5.71e-3)" "unprognostic (3.01e-3)" "unprognostic (1.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.84e-2)" "unprognostic (8.14e-2)" "unprognostic (2.50e-1)" "unprognostic (2.27e-1)" "unprognostic (4.68e-3)" "unprognostic (4.68e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (6.60e-2)" 4.8 0.4 0.0 101.2 0.0 34.8 34.3 0.0 0.0 46.6 0.0 85.6 21.7 5.4 0.0 17.9 10.2 2.5 3.5 0.0 0.0 8.1 6.4 39.4 317.6 0.0 0.0 1.0 1.9 0.0 0.4 0.0 0.1 3.1 78.3 0.0 54.2 1.4 0.0 1.1 103.7 6.8 0.0 102.8 20.3 2.7 0.0 29.0 7.2 0.0 223.2 45.9 2.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.4 0.3 0.1 0.1 0.2 480.8 0.2 0.1 0.5 331.6 0.0 0.0 0.4 0.1 0.1 0.2 0.1 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6195.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-12 ENSG00000278857 "Immunoglobulin kappa variable 1D-12" P01611 2 90159840-90160335 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.6;lymphoid tissue: 47.5;salivary gland: 34.6" "Cell type enriched" "Detected in some" 178 "Plasma cells: 232.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "memory B-cell: 13.0;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 35 "B-cells: 13.0" "Cell line enhanced" "Detected in single" "RH-30: 2.2" HPA048721 Approved "Immunoglobulin genes" NA NA 12000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (1.94e-4)" "unprognostic (9.04e-4)" "unprognostic (3.42e-2)" "prognostic favorable (3.23e-4)" "unprognostic (3.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" 1.7 0.3 0.0 9.6 0.0 0.9 7.6 0.0 0.2 3.0 0.0 26.6 1.6 1.3 0.0 2.2 1.8 0.0 0.3 0.0 0.0 1.7 1.0 11.6 12.5 0.1 0.0 0.2 0.4 0.0 0.2 0.1 0.1 1.1 9.1 0.0 34.6 0.3 0.1 0.2 22.7 5.5 0.0 47.5 9.5 0.2 0.0 1.3 4.0 0.0 9.4 2.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.1 12.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV3D-11 ENSG00000211632 "Immunoglobulin kappa variable 3D-11" A0A0A0MRZ8 2 90172802-90173414 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.6;lymphoid tissue: 58.5;stomach 1: 27.7" "Cell type enriched" "Detected in some" 34 "Plasma cells: 196.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 468 "memory B-cell: 152.5;naive B-cell: 146.1" "Lineage enriched" "Detected in single" 478 "B-cells: 152.5" "Cell line enhanced" "Detected in single" "U-266/70: 2.1" HPA047702 Approved "Immunoglobulin genes" NA NA 6700000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "prognostic favorable (6.40e-5)" "unprognostic (7.90e-3)" "unprognostic (1.91e-2)" "unprognostic (2.24e-3)" "prognostic favorable (5.58e-5)" "unprognostic (2.65e-2)" "unprognostic (2.13e-1)" "unprognostic (2.78e-1)" "unprognostic (6.31e-2)" "unprognostic (3.49e-1)" "unprognostic (3.61e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (1.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.99e-1)" "unprognostic (1.24e-2)" 1.3 0.7 0.3 35.9 0.2 8.9 6.4 0.0 0.1 1.7 0.0 38.6 32.2 0.8 0.0 2.4 2.1 2.7 0.5 0.0 0.1 2.1 1.3 12.4 13.0 0.1 0.3 1.5 0.5 0.0 0.1 0.0 0.1 0.7 26.6 0.0 18.8 0.3 0.0 0.1 23.6 0.7 0.2 29.9 27.7 0.2 0.0 4.2 2.3 0.0 58.5 17.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.8 0.4 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 152.5 0.0 0.0 0.1 146.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 30.2 0.3 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 196.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 IGKV1D-42 ENSG00000211633 "Immunoglobulin kappa variable 1D-42 (non-functional)" A0A075B6H8 2 90190193-90190681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 25.3" "Cell type enriched" "Detected in single" 93 "Plasma cells: 9.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 5.6;naive B-cell: 1.6" "Lineage enriched" "Detected in single" 57 "B-cells: 5.6" "Cell line enriched" "Detected in single" 5 "RPMI-8226: 2.6" HPA048721 Approved "Immunoglobulin genes" NA NA 41000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 37: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "unprognostic (8.08e-6)" "unprognostic (4.83e-2)" "unprognostic (2.22e-2)" "unprognostic (2.51e-3)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (1.66e-5)" "unprognostic (1.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.39e-1)" 0.1 0.0 0.0 7.6 0.0 6.6 10.8 0.0 0.0 0.8 0.0 18.8 7.5 0.2 0.3 1.4 0.2 1.7 0.1 0.0 0.0 0.0 0.3 2.8 2.6 0.1 0.0 4.1 1.1 0.0 0.0 0.0 0.0 0.1 47.7 0.0 8.5 0.0 0.0 0.1 7.9 0.0 0.0 4.2 13.9 0.0 0.0 0.6 0.3 0.0 25.3 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGKV1D-43 ENSG00000242580 "Immunoglobulin kappa variable 1D-43" A0A0B4J1Z2 2 90209873-90210529 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.9;lymphoid tissue: 4.8;stomach 1: 3.6" "Cell type enriched" "Detected in some" 86 "Plasma cells: 695.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 152 "memory B-cell: 13.3;naive B-cell: 17.0" "Lineage enriched" "Detected in single" 171 "B-cells: 17.0" "Cell line enriched" "Detected in single" 310 "RPMI-8226: 79.1" HPA048721 Approved "Immunoglobulin genes" NA NA 380000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (3.32e-5)" "unprognostic (6.71e-2)" "unprognostic (4.01e-2)" "unprognostic (1.27e-2)" "unprognostic (4.57e-3)" "unprognostic (1.37e-3)" "unprognostic (3.15e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-5)" "unprognostic (3.96e-2)" "unprognostic (2.20e-1)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" 0.2 0.0 0.0 2.8 0.0 1.3 1.4 0.0 0.0 0.0 0.0 2.7 1.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 1.1 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 2.0 0.2 0.0 0.0 2.9 0.0 0.0 1.8 3.6 0.0 0.0 0.5 0.1 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 79.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 695.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV1D-8 ENSG00000239819 "Immunoglobulin kappa variable 1D-8" A0A087WSZ0 2 90220727-90221384 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 4.2;lymphoid tissue: 14.2;salivary gland: 5.6" "Cell type enriched" "Detected in some" 29 "Plasma cells: 338.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 323 "memory B-cell: 32.7;naive B-cell: 31.8" "Lineage enriched" "Detected in single" 328 "B-cells: 32.7" "Cell line enriched" "Detected in some" 26 "RPMI-8226: 38.3" HPA048721 Approved "Immunoglobulin genes" NA NA 1900000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (2.93e-4)" "unprognostic (1.03e-3)" "unprognostic (2.23e-2)" "unprognostic (2.76e-3)" "prognostic favorable (8.80e-5)" "unprognostic (6.07e-2)" "unprognostic (9.76e-3)" "unprognostic (2.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.12e-6)" "unprognostic (1.35e-1)" "unprognostic (9.51e-2)" "unprognostic (1.06e-1)" "unprognostic (1.32e-1)" 0.5 0.0 0.0 5.3 0.0 0.7 1.2 0.0 0.0 0.6 0.0 4.2 1.6 0.1 0.0 0.5 0.3 0.0 0.1 0.0 0.0 0.3 0.3 1.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 2.6 0.0 5.6 0.0 0.0 0.0 2.8 0.0 0.0 8.3 1.9 0.0 0.0 1.2 0.6 0.0 14.2 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 338.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 IGKV3D-7 ENSG00000228325 "Immunoglobulin kappa variable 3D-7" A0A0C4DH55 2 90234812-90235370 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.6;lymphoid tissue: 5.5;stomach 1: 4.4;urinary bladder: 5.5" "Cell type enriched" "Detected in single" 415 "Plasma cells: 207.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "memory B-cell: 2.8;naive B-cell: 4.3" "Lineage enriched" "Detected in single" 44 "B-cells: 4.3" "Cell line enriched" "Detected in some" 12 "RPMI-8226: 48.7" HPA047702 Approved "Immunoglobulin genes" NA NA 3700000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA047702: " "unprognostic (2.74e-1)" "unprognostic (8.62e-3)" "unprognostic (6.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.05e-1)" "unprognostic (4.02e-1)" 0.1 0.0 0.0 5.5 0.2 1.3 0.1 0.0 0.1 0.2 0.0 4.0 4.6 0.0 0.0 1.9 0.1 1.5 0.0 0.1 0.1 0.0 0.2 0.5 1.4 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 2.1 0.1 0.0 0.0 4.4 0.0 0.0 3.8 4.4 0.0 0.1 0.2 0.6 0.0 4.3 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 207.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL845331.1 ENSG00000259916 "Putative aquaporin-7-like protein 3" 2 94588522-94604573 "Metabolic proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "adipose tissue: 7.5;breast: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "ASC diff: 1.9" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (8.07e-3)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (9.15e-3)" "unprognostic (6.22e-2)" "unprognostic (4.66e-2)" 7.5 0.1 0.0 0.0 0.5 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TEKT4 MGC27019 ENSG00000163060 "Tektin 4" Q8WW24 2 94871430-94876823 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 13.4" "Group enriched" "Detected in many" 7 "Early spermatids: 137.1;Endometrial ciliated cells: 49.0;Late spermatids: 129.3;Respiratory ciliated cells: 51.6" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 2.7" "Region enhanced" "Detected in single" "midbrain: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "midbrain: 2.9" "HPA048600, HPA053929, HPA069872" Enhanced Uncertain "Intermediate filaments" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "Intermediate filaments" "HPA048600: AB_2680460, HPA053929: AB_2682314, HPA069872: " "unprognostic (1.49e-2)" "unprognostic (4.00e-1)" "prognostic favorable (1.29e-4)" "unprognostic (9.95e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (2.82e-3)" "unprognostic (2.15e-1)" "unprognostic (5.25e-2)" "unprognostic (5.00e-2)" "unprognostic (9.01e-2)" "unprognostic (5.25e-3)" "unprognostic (5.45e-3)" "unprognostic (2.33e-1)" "unprognostic (3.27e-2)" "unprognostic (7.56e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 13.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.7 1.6 0.5 0.3 0.1 0.2 3.6 0.0 1.5 2.9 0.4 1.5 0.1 1.9 0.0 0.0 0.7 0.6 0.5 7.2 4.7 1.8 0.0 0.5 0.1 0.3 1.9 1.9 137.1 49.0 1.3 1.3 0.0 0.0 1.3 0.4 0.5 1.1 0.0 0.9 1.3 0.1 1.8 1.5 0.2 0.0 0.9 0.2 0.0 1.6 0.5 129.3 2.8 0.8 0.0 1.0 2.6 0.0 0.0 2.0 2.3 0.8 0.0 1.2 0.0 0.4 0.0 8.3 51.6 0.0 6.6 0.6 0.9 12.4 2.4 0.0 1.3 0.5 0.5 0.0 0.2 0.4 MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2817.9;vagina: 863.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 373.3;Distal tubular cells: 236.7;Muller glia cells: 91.5;Oligodendrocytes: 168.1;Skeletal myocytes: 82.3;Squamous epithelial cells: 90.9" "Cancer enhanced" "Detected in many" "renal cancer: 101.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 217.6;naive CD4 T-cell: 293.3;naive CD8 T-cell: 138.1;T-reg: 233.6" "Lineage enriched" "Detected in many" 38 "T-cells: 293.3" "Cell line enhanced" "Detected in some" "HDLM-2: 516.4;MOLT-4: 722.0;RPMI-8226: 256.7;RPTEC TERT1: 2531.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065691 Approved "Golgi apparatus,Centrosome" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" Centrosome "HPA065691: AB_2685533" "unprognostic (1.57e-3)" "unprognostic (2.64e-2)" "unprognostic (1.08e-2)" "prognostic unfavorable (5.18e-6)" "unprognostic (1.67e-1)" "unprognostic (2.30e-2)" "unprognostic (5.13e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (3.59e-1)" "unprognostic (4.61e-2)" "unprognostic (3.89e-2)" "prognostic favorable (3.96e-9)" "unprognostic (1.91e-1)" "unprognostic (2.84e-2)" "unprognostic (5.35e-2)" "unprognostic (1.57e-1)" 5.3 1.8 251.3 10.8 333.9 12.7 4.4 264.8 400.2 450.7 177.4 50.8 2.2 2.6 8.3 2817.9 8.9 2.9 17.9 260.8 256.7 400.4 1.7 25.3 25.1 281.3 282.1 3.2 3.0 0.4 3.9 3.4 272.9 21.8 6.3 10.1 544.0 11.1 2.8 12.6 17.0 2.4 264.0 9.4 52.7 1.1 303.2 261.2 21.3 4.3 352.8 15.0 863.2 449.3 51.3 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 12.0 0.0 0.3 2.4 0.2 0.0 0.5 516.4 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 2.4 0.4 0.1 0.1 0.0 722.0 0.2 0.2 0.0 0.0 0.7 0.0 256.7 2531.4 65.3 0.6 0.0 0.1 9.4 1.6 2.1 0.3 0.9 0.8 0.0 0.2 0.1 0.5 0.4 0.3 0.3 0.3 0.4 0.1 0.7 0.6 0.1 4.7 0.3 2.1 3.1 217.6 38.4 0.5 3.5 293.3 138.1 2.6 7.7 0.6 1.2 233.6 71.0 251.3 333.9 264.8 400.2 260.8 256.7 281.3 282.1 272.9 264.0 303.2 449.3 0.9 0.0 0.0 12.1 3.1 1.1 0.2 0.0 1.8 1.5 1.2 0.9 11.3 0.0 1.3 373.3 4.2 0.2 0.9 0.0 236.7 0.1 5.3 4.3 0.6 0.5 0.0 46.1 0.5 0.0 0.0 4.7 24.5 8.2 1.3 3.2 2.5 0.0 0.1 5.0 0.5 0.0 14.2 0.0 1.3 19.5 0.9 1.0 17.8 1.9 2.5 91.5 4.1 6.6 168.1 0.1 0.0 0.0 8.9 0.2 0.0 3.2 0.0 2.7 6.6 82.3 5.3 0.0 0.6 90.9 1.0 0.3 35.8 0.0 0.1 0.8 MRPS5 "MRP-S5, S5mt" ENSG00000144029 "Mitochondrial ribosomal protein S5" P82675 2 95085369-95149434 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055765 Approved Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA055765: AB_2682911" "unprognostic (1.18e-1)" "unprognostic (7.79e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (7.98e-7)" "unprognostic (7.51e-3)" "unprognostic (6.30e-3)" "prognostic unfavorable (7.73e-5)" "unprognostic (8.59e-2)" "unprognostic (1.87e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-2)" "unprognostic (1.29e-1)" "prognostic favorable (6.36e-4)" "unprognostic (1.25e-1)" 26.0 33.6 5.6 3.8 5.7 7.6 22.3 6.9 7.1 24.4 6.3 34.5 6.9 24.1 4.7 34.5 24.3 3.6 53.6 5.7 5.6 34.6 53.6 24.3 5.5 5.7 5.5 24.9 24.1 6.8 19.9 3.7 5.8 18.5 6.9 5.0 24.7 2.9 71.2 19.4 26.8 5.1 5.1 25.0 30.1 19.5 5.8 6.2 23.8 13.7 5.4 23.7 24.8 6.3 18.8 14.8 8.1 7.8 8.6 10.6 15.3 9.5 4.2 7.1 7.6 28.7 12.9 18.4 7.5 8.4 17.1 11.3 14.0 11.8 13.8 13.0 11.2 11.6 12.3 22.8 11.6 16.5 7.3 10.5 9.3 12.0 12.5 9.0 12.3 10.4 18.0 7.8 10.4 15.1 18.6 17.8 9.0 16.5 13.5 10.5 8.0 21.3 17.4 18.5 12.4 7.8 8.2 17.2 17.6 12.8 7.4 16.0 9.5 10.6 12.9 15.1 15.5 7.6 8.9 14.0 8.8 16.3 9.6 2.5 5.4 3.8 3.6 7.2 4.4 4.5 4.8 4.2 4.8 3.3 4.2 4.4 2.2 3.6 7.4 3.3 5.9 4.2 5.6 5.7 6.9 7.1 5.7 5.6 5.7 5.5 5.8 5.1 5.8 6.3 46.3 80.1 84.6 33.3 52.3 34.8 59.1 112.5 56.9 52.8 42.1 40.5 130.2 58.6 74.4 66.2 50.1 81.8 51.2 68.3 185.9 74.8 68.3 48.5 69.9 48.1 59.4 79.3 31.8 55.4 83.8 53.9 51.0 43.0 40.4 90.7 50.3 129.8 74.1 47.1 29.3 65.0 109.9 51.8 41.2 48.9 51.3 55.3 44.4 7.5 61.5 29.7 44.3 30.7 40.3 50.2 44.2 53.4 69.7 68.1 87.3 131.8 72.3 69.0 39.5 52.2 59.5 80.9 99.1 78.7 32.0 39.4 57.4 60.7 104.5 48.2 ZNF514 FLJ14457 ENSG00000144026 "Zinc finger protein 514" Q96K75 2 95145000-95165413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028974 Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA028974: AB_10603845" "unprognostic (8.79e-2)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-1)" "unprognostic (5.99e-2)" "unprognostic (1.11e-2)" "unprognostic (1.80e-2)" "unprognostic (4.68e-2)" "unprognostic (1.42e-2)" "unprognostic (1.73e-1)" "unprognostic (5.17e-2)" "unprognostic (1.80e-3)" "unprognostic (4.33e-2)" "unprognostic (1.91e-1)" "unprognostic (1.00e-1)" "unprognostic (1.79e-2)" 9.3 9.3 13.5 5.9 13.5 2.5 13.2 14.5 14.4 18.3 12.6 14.1 10.2 15.7 26.8 7.8 14.5 5.9 9.6 13.9 13.1 14.2 6.6 9.0 8.7 13.5 12.7 23.3 10.2 12.7 17.2 8.1 14.3 14.8 9.9 29.9 11.7 11.3 14.4 15.0 9.8 10.5 10.9 10.1 10.8 11.2 13.8 10.1 17.9 13.3 8.2 11.4 13.0 15.9 16.7 5.5 16.0 11.5 11.1 15.0 12.2 6.6 7.2 11.0 11.2 9.3 6.5 2.8 3.3 7.1 16.8 10.7 8.6 6.3 12.2 5.5 11.1 3.2 8.8 7.6 4.6 1.9 8.3 8.9 18.9 6.9 4.7 16.4 5.1 9.5 9.3 3.4 8.9 8.2 5.0 10.3 5.3 5.4 6.0 8.5 5.8 6.1 7.1 6.6 14.8 11.2 7.1 3.5 7.6 21.6 6.3 6.4 5.9 7.9 9.9 2.7 5.6 8.5 6.9 4.9 8.2 3.7 5.2 12.7 4.3 8.4 3.9 2.3 4.7 6.8 5.1 3.7 4.2 7.0 8.5 7.0 1.4 6.1 2.6 3.5 6.2 4.2 13.5 13.5 14.5 14.4 13.9 13.1 13.5 12.7 14.3 10.9 13.8 15.9 8.0 9.6 7.9 20.2 4.6 5.6 9.9 8.0 2.2 13.9 9.4 11.9 14.0 12.8 6.7 0.0 18.8 6.3 4.9 6.3 27.4 6.6 44.1 7.1 7.9 8.0 9.6 7.0 22.8 5.2 3.5 7.2 4.6 5.3 1.3 27.9 7.1 9.4 8.3 15.2 22.3 10.6 10.2 5.1 2.2 43.2 10.5 5.4 7.2 13.1 5.9 12.9 8.2 15.1 34.3 4.9 5.1 7.5 3.1 10.0 10.3 18.2 10.3 31.5 6.6 7.9 8.0 20.6 12.5 3.8 6.3 3.7 4.7 8.2 8.7 10.7 ZNF2 "A1-5, Zfp661, ZNF661" ENSG00000275111 "Zinc finger protein 2" Q9BSG1 2 95165432-95184317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041358 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA041358: AB_10795539" "unprognostic (1.18e-1)" "unprognostic (6.41e-3)" "unprognostic (5.81e-2)" "unprognostic (9.29e-2)" "unprognostic (4.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.13e-3)" "prognostic favorable (4.69e-5)" "unprognostic (1.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.37e-2)" "unprognostic (2.63e-2)" "unprognostic (2.66e-3)" "unprognostic (2.57e-2)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" 2.1 2.6 2.3 2.3 2.5 0.7 2.5 2.7 2.9 3.2 2.0 2.4 2.1 2.4 3.2 2.3 2.9 1.5 3.1 2.2 2.2 2.7 1.9 2.4 3.1 2.3 2.3 3.9 2.1 3.8 1.9 2.2 2.4 2.6 1.7 3.0 2.3 3.2 3.4 2.9 1.8 2.6 2.1 2.9 2.5 3.0 2.3 3.2 3.1 3.6 3.2 2.3 1.8 3.0 4.1 3.7 4.5 7.6 6.2 5.1 2.8 4.0 5.7 6.1 7.7 3.9 2.5 2.2 3.0 4.1 4.3 3.0 5.1 3.2 6.1 5.8 4.0 5.8 2.9 4.9 5.1 2.8 3.4 4.4 4.3 5.5 7.8 6.3 5.1 4.6 3.9 1.9 5.9 3.1 4.2 4.1 1.8 3.3 4.9 4.1 7.4 3.3 3.4 2.3 4.0 5.2 4.1 5.7 4.9 3.8 3.6 4.4 4.0 7.0 4.2 5.4 3.6 3.4 3.3 3.0 4.4 3.7 5.2 5.6 3.4 12.9 6.3 4.8 4.4 5.4 4.9 5.5 4.0 5.1 6.3 6.2 2.6 3.5 4.0 3.1 6.2 4.0 2.3 2.5 2.7 2.9 2.2 2.2 2.3 2.3 2.4 2.1 2.3 3.0 2.1 0.0 1.7 3.3 2.0 1.0 0.7 1.1 1.8 3.3 2.3 1.5 2.6 5.7 2.1 1.8 0.0 1.8 2.9 0.8 5.9 1.8 2.7 1.3 2.0 1.9 0.0 1.3 7.7 2.0 1.4 2.1 1.5 1.2 1.3 4.7 2.5 1.6 2.5 1.7 6.2 0.7 0.0 2.5 1.2 0.8 2.1 2.2 0.0 3.7 0.5 4.2 4.1 7.1 5.7 0.9 0.5 3.0 1.4 0.9 1.5 2.8 2.5 2.7 6.6 1.6 2.0 5.5 7.5 0.9 1.1 1.6 1.6 2.8 1.1 0.7 AC092835.1 ENSG00000233757 "Novel C2H2 type zinc finger protein" 2 95207535-95259774 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adipocytes: 1.1;Endometrial stromal cells: 1.9;Granulosa cells: 2.2;Theca cells: 1.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (7.89e-2)" "unprognostic (3.55e-1)" "unprognostic (9.21e-2)" "unprognostic (9.21e-3)" "unprognostic (1.74e-2)" "unprognostic (2.44e-1)" "unprognostic (9.49e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (1.73e-1)" "unprognostic (7.72e-2)" "unprognostic (6.65e-3)" "unprognostic (1.50e-1)" "unprognostic (1.02e-1)" "unprognostic (2.96e-1)" "unprognostic (7.92e-2)" "unprognostic (4.47e-2)" 0.7 0.4 0.8 0.6 1.0 0.2 0.7 1.1 1.7 0.9 0.0 0.6 0.4 1.2 0.2 0.5 0.7 0.6 0.7 0.7 0.2 0.7 0.1 0.6 0.5 0.4 0.4 0.9 1.0 1.4 0.3 0.8 0.7 0.5 0.4 1.6 0.8 0.9 0.5 0.2 0.3 0.8 0.0 1.0 0.5 2.1 0.8 1.7 1.5 0.3 0.7 0.5 0.4 3.2 2.0 0.6 3.7 4.1 1.0 2.0 2.3 0.8 0.8 1.9 2.0 0.5 0.5 1.6 0.4 0.8 1.5 1.6 3.1 1.1 2.6 0.0 0.4 0.3 1.6 0.0 0.5 0.0 2.8 0.6 1.1 1.5 3.5 1.5 1.0 4.3 0.0 0.0 1.4 0.0 5.2 0.4 4.5 0.5 0.0 4.6 0.4 0.0 0.6 0.8 5.3 2.4 0.5 1.1 0.0 3.8 1.0 0.8 1.1 0.7 2.5 0.6 0.0 0.0 0.6 0.1 0.0 0.0 2.1 0.0 0.1 0.2 0.7 0.0 0.0 0.5 0.1 0.2 0.2 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.8 1.0 1.1 1.7 0.7 0.2 0.4 0.4 0.7 0.0 0.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.9 0.0 0.0 0.6 0.0 0.0 0.1 0.7 0.0 0.0 0.6 0.0 0.5 1.9 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.5 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Club cells: 39.9;Collecting duct cells: 33.1;Squamous epithelial cells: 37.2;Urothelial cells: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 79.5;CAPAN-2: 135.9;HaCaT: 73.2;hTCEpi: 78.4;MCF7: 62.1;RT4: 83.8;SK-BR-3: 117.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" 0.7 0.3 1.1 1.5 1.3 0.3 10.3 1.0 2.1 16.6 0.2 11.4 10.5 1.9 27.9 88.1 5.5 27.0 1.1 0.9 0.6 32.4 0.8 1.7 0.1 1.4 0.7 1.1 10.2 25.5 1.5 4.5 1.2 24.7 9.8 0.4 35.2 27.7 0.7 60.0 4.8 0.8 0.3 0.6 26.3 0.6 1.4 2.0 11.9 0.2 7.9 25.7 37.9 2.1 79.5 0.1 0.2 0.8 0.3 0.1 38.5 0.1 0.2 0.3 0.4 0.8 135.9 0.0 0.0 0.1 0.1 73.2 0.0 42.4 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 78.4 0.1 0.4 1.9 0.0 0.1 0.0 0.1 0.0 62.1 0.4 0.5 0.1 3.7 0.5 0.2 0.0 0.1 0.2 83.8 0.6 0.2 0.0 117.7 0.1 0.9 37.2 0.1 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.0 2.1 0.9 0.6 1.4 0.7 1.2 0.3 1.4 2.1 0.4 3.2 4.2 1.3 0.1 6.6 25.2 27.6 14.2 0.4 29.1 14.9 1.7 37.1 39.9 33.1 4.2 19.0 0.1 8.0 11.7 15.6 0.5 2.7 0.6 0.9 3.6 0.0 0.6 11.0 3.5 0.6 25.5 5.5 0.0 0.7 0.0 0.0 2.4 0.0 1.2 10.4 12.2 0.0 0.8 1.4 0.3 0.2 7.2 0.0 0.6 0.1 0.0 1.5 3.2 17.5 12.4 0.7 0.0 14.1 0.7 0.1 12.3 1.1 0.0 0.4 2.2 0.6 0.1 37.2 12.8 11.2 0.2 0.8 17.4 37.5 KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.0;Leydig cells: 25.4;Oligodendrocyte precursor cells: 54.8;Peritubular cells: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 13.8;BJ hTERT+: 18.0;hTERT-RPE1: 23.2;RPTEC TERT1: 35.2;U-138 MG: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA066717: , HPA069797: AB_2686199" "unprognostic (1.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.33e-3)" "prognostic unfavorable (1.58e-5)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (2.32e-1)" "unprognostic (4.09e-1)" "unprognostic (1.44e-3)" "unprognostic (8.90e-2)" "unprognostic (6.51e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-1)" 6.7 1.5 21.8 0.8 20.0 0.0 5.4 15.2 31.2 10.7 12.2 9.8 1.2 10.6 3.6 2.4 10.1 1.5 6.0 22.1 16.8 8.4 2.0 2.4 0.4 15.4 17.2 10.1 2.4 27.0 6.4 5.3 15.2 9.3 0.9 0.5 5.6 14.7 1.5 6.0 3.7 5.1 15.3 2.6 5.5 12.2 18.0 24.4 19.7 1.8 0.5 9.0 10.6 19.3 13.8 0.0 0.8 6.1 5.3 4.2 0.0 6.3 18.0 10.1 9.3 0.0 0.0 0.0 0.6 8.3 5.5 0.2 4.0 1.1 4.3 0.0 1.4 0.0 1.8 0.0 2.2 0.0 0.0 2.9 3.6 2.2 10.0 23.2 0.0 1.0 0.0 0.0 0.8 8.0 0.1 0.0 0.1 0.0 3.7 0.0 0.0 0.0 35.2 0.0 0.7 0.2 0.3 0.3 6.8 0.0 0.3 0.1 0.3 16.3 3.8 0.0 4.9 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 20.0 15.2 31.2 22.1 16.8 15.4 17.2 15.2 15.3 18.0 19.3 0.4 0.0 1.1 13.4 0.5 0.4 0.8 0.0 1.2 8.1 1.0 1.0 1.6 0.0 0.0 1.8 0.0 0.0 0.0 0.2 7.9 0.2 0.6 0.3 3.7 1.0 4.2 0.0 39.0 0.0 0.1 3.5 0.0 0.3 0.0 7.5 0.0 0.5 0.1 0.0 5.1 0.1 0.0 0.0 0.4 1.3 25.4 0.1 7.2 1.9 0.6 0.5 0.0 54.8 3.0 0.2 0.0 42.9 0.0 0.5 1.0 1.5 0.0 0.0 0.0 8.3 3.7 0.1 0.9 0.2 0.9 0.0 0.0 1.5 0.3 0.1 FAHD2A CGI-105 ENSG00000115042 "Fumarylacetoacetate hydrolase domain containing 2A" Q96GK7 2 95402708-95416616 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 114.8" "Cell type enhanced" "Detected in all" "Early spermatids: 101.7;Hepatocytes: 99.3;Proximal enterocytes: 104.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042145, HPA044987, CAB045971, CAB045972" Enhanced NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 2: Hepatocytes - Metabolism" "CAB045971: AB_11126570, CAB045972: AB_11140511, HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.52e-2)" "unprognostic (1.25e-3)" "unprognostic (9.36e-2)" "unprognostic (1.27e-2)" "unprognostic (7.77e-3)" "unprognostic (6.82e-2)" "unprognostic (2.80e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-2)" "unprognostic (1.61e-1)" "unprognostic (4.58e-2)" "unprognostic (7.30e-2)" "unprognostic (3.24e-2)" "unprognostic (1.17e-2)" "unprognostic (1.95e-1)" "unprognostic (1.88e-2)" "unprognostic (1.55e-2)" 21.0 22.1 22.6 8.7 24.2 14.7 21.8 25.5 29.7 18.4 18.8 18.3 32.4 19.0 5.3 13.3 17.8 10.9 39.3 23.5 22.4 28.6 114.8 13.9 10.9 22.3 22.4 22.6 30.0 18.1 12.3 10.8 22.7 15.5 13.9 5.9 86.2 12.2 37.8 18.5 25.4 15.3 21.2 14.6 26.1 29.9 23.3 18.6 37.8 57.9 12.2 14.3 15.7 27.6 30.2 27.9 31.7 20.4 34.4 31.1 22.4 28.2 47.5 32.5 51.6 17.6 12.9 18.5 12.1 29.1 41.0 16.2 22.8 25.7 32.3 16.0 27.9 14.9 13.2 29.1 44.3 22.8 8.2 29.9 28.6 30.0 37.9 51.6 43.2 35.6 21.6 41.1 41.6 36.6 40.6 31.1 10.2 17.6 27.2 29.9 20.0 52.0 36.3 12.1 18.9 9.3 16.8 27.0 33.2 39.3 16.9 9.0 20.4 41.2 28.3 17.6 19.6 44.0 20.3 18.8 28.0 20.5 20.9 3.3 15.7 8.1 18.2 17.8 20.7 15.5 16.7 17.6 23.3 10.4 16.8 14.2 1.0 12.3 9.0 27.3 19.6 14.4 22.6 24.2 25.5 29.7 23.5 22.4 22.3 22.4 22.7 21.2 23.3 27.6 14.6 9.6 12.5 10.7 13.8 9.8 13.8 14.6 21.1 17.6 26.6 26.4 36.8 28.6 16.8 29.5 10.4 30.3 16.6 14.4 70.5 29.5 101.7 11.2 10.5 13.9 4.9 14.5 15.2 23.1 14.7 21.4 21.9 7.7 4.5 32.7 16.4 99.3 26.0 16.8 13.2 17.3 10.2 12.0 8.3 87.1 37.0 11.0 17.8 2.8 19.8 22.2 13.4 3.5 10.8 18.7 17.3 52.3 23.9 15.4 104.6 52.7 15.0 18.8 13.1 15.3 21.3 49.1 19.1 19.0 7.7 17.1 12.4 36.5 23.9 12.1 TRIM43B ENSG00000144010 "Tripartite motif containing 43B" A6NCK2 2 95477164-95484731 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042223, HPA042772" Uncertain NA NA "HPA042223: AB_10962361, HPA042772: AB_10964436" "unprognostic (3.93e-1)" "unprognostic (1.24e-1)" 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM43 TRIM43A ENSG00000144015 "Tripartite motif containing 43" Q96BQ3 2 95592001-95599778 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.4;Spermatogonia: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042223, HPA042772" Uncertain NA NA "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA042223: AB_10962361, HPA042772: AB_10964436" "unprognostic (7.17e-3)" "unprognostic (1.42e-1)" "unprognostic (9.27e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKRD36C DKFZp667P0924 ENSG00000174501 "Ankyrin repeat domain 36C" Q5JPF3 2 95836919-95991831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 615.1;Gastric mucus-secreting cells: 498.9;Inhibitory neurons: 290.7;Pancreatic endocrine cells: 311.5;Urothelial cells: 411.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "PC-3: 30.9" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "HPA051757: AB_2681594, HPA057661: AB_2683494" "unprognostic (2.21e-1)" "unprognostic (5.39e-2)" "unprognostic (6.32e-2)" "unprognostic (2.50e-1)" "unprognostic (1.83e-1)" "unprognostic (3.79e-3)" "unprognostic (1.29e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.44e-2)" "unprognostic (5.29e-3)" "unprognostic (5.35e-6)" "unprognostic (9.99e-2)" "unprognostic (2.47e-1)" "unprognostic (3.44e-2)" "unprognostic (1.79e-1)" 2.0 1.5 5.3 2.1 9.3 16.3 6.1 24.0 8.9 2.6 1.5 2.8 1.2 3.8 2.3 2.3 3.1 4.8 1.4 4.2 9.3 1.2 0.6 2.6 3.5 9.4 5.9 6.0 1.8 1.6 1.6 1.5 11.3 1.9 2.6 10.6 14.6 1.5 0.7 3.6 1.6 1.9 2.6 2.9 5.4 12.0 9.7 6.5 1.6 0.9 2.9 3.2 1.9 25.8 8.4 1.6 3.3 2.3 2.1 5.7 1.3 1.9 1.4 2.5 3.3 1.9 1.9 8.3 2.5 1.4 2.5 1.9 3.0 1.5 3.2 4.8 4.1 3.2 4.5 2.4 0.5 9.9 2.4 1.7 1.2 2.0 1.0 2.5 4.3 11.7 3.3 10.2 2.8 1.2 7.7 3.7 0.7 0.4 30.9 4.0 2.5 3.3 1.3 1.6 3.0 2.7 1.3 2.1 1.3 1.2 1.0 2.3 4.8 3.1 3.4 2.4 2.4 3.8 3.4 8.9 0.9 6.7 1.3 48.0 3.3 2.8 20.8 0.5 13.4 17.1 16.7 13.9 2.5 19.5 14.5 14.2 0.2 12.6 1.0 35.0 15.6 1.3 5.3 9.3 24.0 8.9 4.2 9.3 9.4 5.9 11.3 2.6 9.7 25.8 32.3 38.5 19.9 123.1 26.9 10.7 53.4 33.6 11.4 84.4 38.4 20.8 29.1 4.3 91.0 9.2 79.2 0.3 47.2 23.5 0.0 226.3 118.4 42.6 28.7 25.8 21.0 27.1 227.9 615.1 0.8 26.3 498.9 25.8 34.1 41.3 15.4 1.5 8.3 33.7 290.7 70.2 12.2 7.0 14.7 17.7 32.6 15.9 14.2 46.9 27.4 15.8 50.4 147.8 177.7 311.5 8.4 36.5 48.7 145.8 7.7 0.9 82.3 72.9 19.7 56.1 31.0 178.7 22.4 7.7 7.4 0.3 47.5 13.1 22.0 411.9 GPAT2 CT123 ENSG00000186281 "Glycerol-3-phosphate acyltransferase 2, mitochondrial" Q6NUI2 2 96021946-96039451 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Breast glandular cells: 84.5;Sertoli cells: 98.6;Smooth muscle cells: 30.3;Spermatocytes: 64.4;Spermatogonia: 45.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ: 8.2;BJ hTERT+ SV40 Large T+: 19.6;BJ hTERT+ SV40 Large T+ RasG12V: 11.6;OE19: 13.9;U-2 OS: 10.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036841 Uncertain Approved Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" Mitochondria "HPA036841: AB_10601479" "unprognostic (1.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.69e-2)" "unprognostic (3.83e-1)" "unprognostic (1.44e-1)" "unprognostic (2.38e-3)" "unprognostic (4.99e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (5.96e-2)" "unprognostic (4.67e-2)" "unprognostic (7.43e-6)" "unprognostic (2.11e-1)" "unprognostic (7.68e-2)" "unprognostic (3.49e-1)" "unprognostic (3.65e-1)" 5.8 0.8 1.5 1.4 1.7 1.2 4.5 1.4 1.7 2.4 3.3 1.8 0.2 1.5 3.1 0.8 1.6 1.6 7.4 1.2 1.3 1.6 1.0 1.3 2.4 1.7 1.6 1.2 1.6 0.1 0.6 1.4 2.0 1.1 1.0 0.2 2.2 2.8 2.1 1.1 2.2 1.6 1.3 4.6 2.1 7.6 2.4 0.8 1.7 3.0 1.9 2.0 1.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.2 0.0 19.6 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.4 0.0 2.8 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 1.0 0.7 1.0 1.6 0.5 0.7 0.4 2.4 0.3 1.1 0.0 0.1 1.0 0.0 0.5 0.6 1.5 1.7 1.4 1.7 1.2 1.3 1.7 1.6 2.0 1.3 2.4 2.1 12.9 0.0 1.1 0.3 3.5 1.0 1.1 0.7 0.6 0.7 84.5 3.4 1.3 1.5 0.5 1.8 0.0 0.1 1.7 3.1 1.9 2.2 1.9 0.1 0.5 6.5 0.0 0.8 1.0 2.0 0.6 3.3 1.5 0.5 1.3 0.2 10.8 0.0 2.4 8.4 0.4 0.6 0.0 0.8 2.1 5.3 0.6 1.5 1.8 1.9 0.7 1.0 1.0 0.0 1.4 0.8 1.3 0.0 3.6 0.4 0.0 0.2 0.2 0.4 98.6 3.2 30.3 64.4 45.3 0.4 0.1 0.1 2.2 0.3 2.1 1.8 ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 9.0;Langerhans cells: 8.0;Sertoli cells: 32.9;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;EFO-21: 1.0" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in some" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" 6.4 2.1 1.5 0.3 1.7 0.8 3.0 1.4 2.7 1.5 4.9 2.3 0.3 1.9 3.8 0.7 3.0 0.6 10.1 1.2 1.4 5.1 7.0 0.5 0.2 1.8 1.6 1.7 0.8 0.5 0.5 0.8 1.7 1.4 0.3 0.0 2.2 1.5 6.4 1.9 2.6 0.7 1.3 8.6 2.2 1.6 2.6 0.2 1.3 5.0 0.1 2.5 1.8 2.4 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 2.7 1.2 1.4 1.8 1.6 1.7 1.3 2.6 2.4 2.9 0.0 0.0 0.0 0.9 1.1 0.7 0.7 0.6 0.0 0.9 0.9 2.5 0.0 1.5 1.8 0.0 0.8 2.9 0.1 0.0 0.2 0.0 2.2 1.0 2.4 2.4 0.0 0.0 0.6 0.2 1.0 1.1 9.0 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.2 0.0 0.3 8.0 0.0 1.8 5.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.4 0.7 0.0 0.1 1.4 0.0 32.9 0.7 13.3 0.0 0.3 0.6 1.4 0.4 2.8 0.1 0.1 0.3 ASTL "ovastacin, SAS1B" ENSG00000188886 "Astacin like metalloendopeptidase" Q6HA08 2 96123850-96138436 "Predicted intracellular proteins" Fertilization "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 4.1;brain: 4.3" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 1.0;Macrophages: 1.2;T-cells: 1.7" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA015620 Uncertain "Intracellular and membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" "HPA015620: AB_1845121" "unprognostic (3.21e-2)" "unprognostic (1.45e-2)" "unprognostic (3.87e-2)" "unprognostic (3.45e-4)" "unprognostic (1.00e-2)" "unprognostic (3.03e-2)" "unprognostic (3.53e-2)" "unprognostic (5.12e-2)" "unprognostic (3.62e-1)" "unprognostic (3.40e-1)" "unprognostic (1.95e-1)" "unprognostic (2.61e-5)" "unprognostic (3.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" 0.1 0.0 0.9 0.3 0.2 4.1 0.1 0.7 4.3 0.0 0.0 0.2 0.1 0.1 0.2 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.2 1.0 0.0 0.9 0.4 0.0 0.0 0.7 0.2 0.3 0.0 0.7 0.0 0.0 0.3 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.7 4.3 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.5 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.0 0.0 DUSP2 PAC-1 ENSG00000158050 "Dual specificity phosphatase 2" Q05923 2 96143169-96145440 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 129.5" "Cell type enhanced" "Detected in many" "dendritic cells: 919.7;Glandular and luminal cells: 321.1;Langerhans cells: 924.0;Macrophages: 353.9;T-cells: 764.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebral cortex: 55.0" "Immune cell enhanced" "Detected in all" "gdT-cell: 199.3" "Group enriched" "Detected in all" 10 "NK-cells: 148.1;T-cells: 199.3" "Cell line enhanced" "Detected in many" "Daudi: 30.4;HeLa: 29.7;JURKAT: 27.6;Karpas-707: 33.8;NB-4: 29.1;RT4: 34.2;SCLC-21H: 29.6;U-698: 43.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA071920 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane" Nucleoplasm "HPA071920: AB_2686472" "unprognostic (2.69e-3)" "unprognostic (6.70e-3)" "unprognostic (1.15e-1)" "unprognostic (5.46e-3)" "unprognostic (3.32e-2)" "unprognostic (8.54e-2)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (2.86e-1)" "unprognostic (3.66e-2)" "unprognostic (3.10e-1)" "unprognostic (6.30e-2)" "prognostic unfavorable (4.97e-5)" "unprognostic (1.82e-1)" "unprognostic (2.41e-1)" "unprognostic (3.94e-2)" "unprognostic (1.31e-3)" 17.0 6.0 7.6 18.6 11.6 129.5 5.5 7.5 55.0 8.1 9.2 4.5 1.6 7.0 7.7 6.8 7.6 12.5 19.5 13.4 6.2 12.7 7.5 18.2 47.1 8.0 6.3 7.8 2.3 1.7 35.1 1.3 6.7 17.6 2.0 0.4 3.9 61.5 2.8 26.0 11.8 3.4 6.7 42.0 7.4 3.6 6.9 47.3 6.7 3.7 24.6 39.5 9.0 9.3 3.2 0.0 0.2 0.2 0.4 0.5 4.4 3.7 0.0 5.3 5.1 8.9 0.6 30.4 10.6 4.1 0.0 2.2 7.5 0.0 1.0 0.5 0.0 0.7 29.7 0.0 1.9 12.8 2.6 0.9 2.0 0.9 0.0 0.1 0.0 27.6 0.0 33.8 0.2 5.2 25.5 29.1 6.5 0.8 10.6 0.0 0.4 24.3 0.2 34.2 29.6 1.5 1.4 0.3 5.6 0.0 2.0 14.4 0.1 0.0 7.9 0.0 1.7 2.3 3.9 43.2 0.0 13.9 0.3 2.3 4.3 1.0 199.3 10.5 95.4 17.5 46.7 176.2 10.7 13.9 32.0 99.3 6.1 148.1 9.1 3.0 16.1 40.5 7.6 11.6 7.5 55.0 13.4 6.2 8.0 6.3 6.7 6.7 6.9 9.3 50.8 0.0 7.7 0.7 303.7 96.7 155.0 31.3 70.6 27.8 65.8 72.0 37.8 2.8 12.0 9.2 22.9 0.9 919.7 20.4 1.9 0.9 0.9 115.6 62.7 28.7 87.8 50.5 5.2 1.4 1.7 22.8 86.6 321.1 104.3 7.4 12.8 3.9 80.2 0.0 1.4 37.5 8.2 40.4 924.0 1.4 1.8 353.9 144.1 1.9 3.4 1.5 90.6 1.0 0.5 1.0 2.5 1.9 268.5 70.4 1.6 1.4 2.7 3.6 0.0 14.7 26.6 0.6 4.8 50.4 109.7 1.6 764.7 3.0 51.6 41.1 STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB033965: AB_2302780, HPA064958: AB_2685391, HPA064978: AB_2685397" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (1.67e-1)" "prognostic unfavorable (8.56e-5)" "prognostic favorable (3.89e-6)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.22e-4)" "unprognostic (2.72e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.38e-6)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (2.64e-2)" "unprognostic (2.42e-2)" 44.7 54.3 57.8 46.7 62.4 34.3 43.9 61.9 53.2 33.9 60.6 57.6 55.7 29.8 30.5 36.8 44.0 29.1 98.5 49.8 61.4 80.3 62.8 61.1 70.6 56.4 55.5 29.4 42.2 69.7 23.6 29.3 54.9 39.0 56.2 54.4 65.2 45.7 202.5 35.2 45.4 37.6 60.5 53.1 44.6 21.1 66.9 56.2 56.6 174.0 86.9 42.1 27.0 74.4 128.8 79.1 102.3 106.2 134.9 66.9 150.1 122.6 107.0 121.2 129.6 188.8 117.7 228.7 129.0 98.6 95.8 102.3 183.3 106.4 157.3 147.2 131.9 204.1 74.3 218.3 62.2 158.1 106.9 65.4 77.9 101.0 99.1 77.2 123.2 92.6 211.1 89.2 108.8 113.0 175.9 161.0 173.3 110.3 115.2 171.6 156.4 227.1 73.2 162.2 191.6 90.5 62.5 201.8 115.8 126.0 60.5 171.6 103.8 100.1 100.4 112.0 125.8 113.9 114.0 201.7 92.8 174.9 112.6 35.6 25.4 22.7 25.6 30.2 26.1 42.6 21.5 26.6 36.2 37.8 23.6 23.4 3.0 30.8 19.9 42.2 41.5 26.0 57.8 62.4 61.9 53.2 49.8 61.4 56.4 55.5 54.9 60.5 66.9 74.4 32.0 134.6 44.2 21.5 71.2 63.7 43.2 34.3 101.9 39.5 58.1 50.2 176.9 55.8 47.1 46.0 108.4 35.8 83.8 63.3 74.3 32.4 2.5 34.5 43.2 49.9 44.4 48.6 25.6 38.0 40.3 31.3 37.8 48.6 15.8 45.4 41.7 114.7 71.0 40.4 23.8 58.4 24.4 122.4 102.3 6.9 23.3 54.4 42.7 20.6 95.8 38.4 30.9 19.1 42.6 35.8 26.6 25.2 120.6 68.4 50.1 65.7 31.8 58.1 26.3 43.5 43.0 22.7 35.1 75.4 57.4 35.4 62.9 36.8 81.9 38.8 TMEM127 "FLJ20507, FLJ22257" ENSG00000135956 "Transmembrane protein 127" O75204 2 96248514-96265997 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (5.15e-3)" "unprognostic (2.67e-1)" "unprognostic (1.72e-2)" "unprognostic (6.51e-2)" "unprognostic (5.82e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (6.59e-4)" "unprognostic (6.73e-2)" "unprognostic (4.25e-1)" "unprognostic (1.06e-2)" "unprognostic (7.50e-2)" "unprognostic (2.17e-1)" "prognostic favorable (6.69e-5)" "unprognostic (3.59e-1)" "unprognostic (1.52e-1)" "unprognostic (5.15e-2)" "unprognostic (3.65e-2)" 29.3 34.6 25.9 28.5 24.6 53.0 25.6 20.1 30.6 30.7 15.7 34.4 32.6 30.0 21.4 40.0 25.2 32.3 67.8 26.7 23.6 29.5 35.4 31.6 21.4 24.5 26.3 31.9 28.5 73.1 29.4 26.8 24.5 26.1 30.5 27.6 39.7 42.4 25.9 33.0 34.7 35.1 21.1 34.7 27.8 10.2 29.7 19.1 26.2 30.6 25.4 38.6 27.8 21.9 28.8 38.0 19.9 30.7 86.0 43.3 36.7 36.9 65.9 38.6 35.2 37.9 40.0 17.9 52.8 73.3 67.8 45.1 23.1 34.2 26.8 36.1 17.8 31.2 17.6 37.5 55.4 26.7 54.0 52.7 48.0 48.0 35.3 51.4 44.5 12.1 19.5 37.6 39.8 32.8 17.6 16.8 27.3 33.9 40.4 16.4 25.0 26.9 42.9 48.7 22.3 23.4 27.1 63.8 31.3 40.2 23.6 28.2 52.5 63.9 36.2 55.9 25.8 28.2 29.6 14.1 42.6 30.9 34.7 3.9 6.3 8.2 2.8 6.6 3.0 1.8 2.1 3.0 4.3 1.9 1.6 2.2 14.3 1.5 5.3 2.5 1.6 3.2 25.9 24.6 20.1 30.6 26.7 23.6 24.5 26.3 24.5 21.1 29.7 21.9 24.8 19.2 15.3 7.2 13.4 17.2 16.6 14.5 12.0 22.1 20.0 12.8 39.6 22.8 20.2 27.6 27.1 11.4 19.3 88.2 15.6 29.7 5.2 16.4 15.1 23.1 16.3 9.0 12.9 34.8 13.1 16.7 14.8 28.8 13.9 13.6 29.6 35.7 37.7 21.9 15.7 26.7 12.2 59.8 33.2 5.8 13.7 34.0 16.0 5.6 41.9 7.8 15.5 8.0 6.6 41.0 35.1 17.0 13.0 23.1 43.9 13.3 15.7 16.9 6.6 18.5 19.4 9.1 2.9 12.6 23.3 24.2 14.3 15.9 18.6 34.1 CIAO1 "CIA1, WDR39" ENSG00000144021 "Cytosolic iron-sulfur assembly component 1" O76071 2 96266159-96274173 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017882 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Cytosol "HPA017882: AB_1846738" "unprognostic (2.34e-1)" "unprognostic (4.68e-2)" "unprognostic (5.32e-2)" "prognostic unfavorable (4.13e-5)" "unprognostic (1.55e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (9.86e-2)" "unprognostic (5.16e-2)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (8.72e-2)" "unprognostic (2.33e-1)" "unprognostic (5.26e-2)" "unprognostic (2.15e-2)" 18.4 32.4 26.8 17.0 28.3 12.1 19.4 30.2 29.7 18.9 26.3 16.8 20.1 14.8 18.0 20.1 19.7 15.1 30.4 27.8 27.8 31.0 32.8 17.6 22.3 27.7 27.6 18.6 17.9 36.2 13.4 18.7 28.3 16.9 17.6 17.4 23.6 19.5 27.8 19.3 17.6 16.5 28.9 21.3 16.7 17.1 28.6 22.2 20.5 28.0 21.3 18.6 13.9 30.2 31.8 27.2 28.8 32.3 49.8 40.9 32.0 27.1 31.9 37.5 39.8 44.1 23.0 44.6 46.6 29.8 42.0 28.0 40.8 29.7 33.4 25.0 58.0 28.9 19.4 47.4 28.8 37.8 32.2 35.1 34.5 28.5 43.2 35.9 39.9 33.8 36.9 29.8 35.9 38.1 42.2 40.8 51.3 44.5 58.0 38.3 33.2 47.3 42.6 31.6 36.0 42.2 19.9 48.0 53.1 40.1 24.8 41.4 30.4 26.2 35.4 36.7 29.3 43.5 49.6 30.1 38.4 37.9 31.4 30.9 27.7 34.2 27.8 23.8 31.9 20.9 25.8 29.8 29.1 24.9 24.3 28.5 23.6 30.0 33.8 18.8 23.5 33.0 26.8 28.3 30.2 29.7 27.8 27.8 27.7 27.6 28.3 28.9 28.6 30.2 33.3 28.9 31.4 26.8 32.4 29.1 28.7 39.0 35.9 24.3 23.2 28.4 27.0 15.7 31.6 14.7 14.6 59.3 42.5 21.8 39.2 40.0 25.0 21.2 30.7 30.1 15.7 32.4 44.5 33.6 60.1 32.6 28.1 21.2 37.2 33.3 19.2 27.4 45.2 26.9 36.6 21.1 44.7 23.4 29.6 25.8 20.2 30.6 19.6 20.6 40.6 19.0 42.2 25.1 25.2 35.5 13.0 16.6 44.8 51.7 43.6 72.7 36.2 24.0 32.9 27.3 34.4 42.5 42.3 43.5 34.5 49.8 38.6 54.5 23.6 43.0 SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274338-96321271 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029321 Approved Supported Nucleoplasm NA NA 78000 "Cluster 41: Basophils - Cellular respiration" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA029321: AB_10604096" "unprognostic (2.63e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.89e-4)" "unprognostic (1.50e-1)" "unprognostic (1.09e-1)" "unprognostic (2.48e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (2.69e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" 26.5 21.8 11.2 38.1 11.3 58.8 38.6 16.9 12.1 31.9 25.5 29.6 29.4 41.0 20.2 29.5 39.8 25.8 26.9 9.9 11.1 28.8 29.3 29.3 43.2 13.1 10.3 53.2 34.3 52.4 19.7 39.2 12.0 31.6 34.6 67.6 35.1 33.0 47.4 30.8 30.3 38.5 12.2 36.5 30.6 40.4 9.8 73.5 37.4 38.7 52.3 30.1 21.6 14.6 97.8 107.7 144.1 106.1 63.1 57.1 131.5 67.3 80.6 119.5 112.9 197.3 69.3 169.3 101.3 83.3 178.9 74.9 264.4 88.8 130.8 94.3 139.4 221.6 169.8 106.7 40.9 171.2 92.4 58.1 53.7 133.2 112.0 61.3 97.3 98.3 198.2 112.3 68.3 82.3 158.8 49.4 182.8 77.9 102.4 185.0 139.3 107.4 43.8 145.4 159.8 150.5 107.7 88.7 65.4 165.0 86.4 100.5 86.2 98.3 117.2 101.3 96.2 101.0 134.0 207.6 66.2 109.0 106.2 16.7 4.7 6.0 7.9 5.0 8.9 5.7 6.0 9.5 5.6 6.1 5.2 7.1 4.7 7.3 6.1 5.8 6.8 5.5 11.2 11.3 16.9 12.1 9.9 11.1 13.1 10.3 12.0 12.2 9.8 14.6 47.3 44.8 53.9 21.9 57.4 29.6 27.2 35.5 38.1 79.3 40.2 42.4 35.2 54.3 46.2 51.5 104.3 43.2 64.2 43.4 5.9 42.6 29.3 42.4 48.7 44.8 46.7 54.1 21.2 46.7 36.1 37.9 52.0 48.8 25.3 79.0 40.4 49.4 35.1 87.5 21.1 40.6 34.6 31.9 33.2 18.2 57.5 35.2 17.8 16.9 45.2 79.1 73.2 17.1 16.7 46.1 30.7 55.3 68.3 34.8 47.3 17.9 50.7 135.2 65.7 54.7 45.5 77.6 56.0 38.7 33.0 44.6 71.6 53.3 49.4 30.3 ITPRIPL1 KIAA1754L ENSG00000198885 "ITPRIP like 1" Q6GPH6 2 96325317-96330517 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Group enriched" "Detected in many" 10 "Early spermatids: 170.7;Late spermatids: 145.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 12.9" "Lineage enriched" "Detected in many" 5 "T-cells: 12.9" "Cell line enhanced" "Detected in many" "HEK 293: 30.9;HEL: 32.0;MOLT-4: 34.5;RPMI-8226: 33.0;U-698: 35.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.26e-3)" "unprognostic (3.56e-3)" "unprognostic (4.78e-2)" "unprognostic (9.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.56e-4)" "unprognostic (3.04e-2)" "unprognostic (2.87e-1)" "unprognostic (6.50e-2)" "unprognostic (5.36e-2)" "unprognostic (8.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.41e-5)" "unprognostic (4.97e-2)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (6.39e-2)" 3.4 0.4 0.5 2.9 1.0 1.1 3.8 3.2 0.7 0.9 0.3 0.9 1.2 0.5 0.5 1.5 0.8 1.6 1.3 0.5 0.5 0.5 0.5 1.4 3.9 0.9 0.5 0.4 1.4 0.5 0.4 1.2 0.8 2.0 0.9 0.9 7.5 1.5 1.5 0.8 1.7 1.0 0.6 2.6 1.2 27.8 0.6 5.1 0.7 2.0 4.2 1.5 1.2 0.8 0.0 0.0 7.3 0.1 0.8 1.9 8.3 1.6 8.7 7.2 14.1 3.3 0.3 0.0 0.1 3.1 0.1 0.7 25.4 0.0 8.1 15.7 30.9 32.0 0.2 14.4 3.9 0.1 0.0 5.4 0.0 8.3 0.0 0.0 4.7 20.4 0.0 10.6 0.2 0.0 34.5 5.0 10.5 0.0 0.0 22.7 23.1 33.0 0.3 0.0 21.2 14.2 0.0 0.0 0.1 4.4 0.0 5.3 2.4 0.0 0.8 0.1 0.1 15.4 21.4 35.3 4.1 0.0 6.8 0.4 0.2 0.0 10.2 0.2 12.9 1.6 3.3 9.7 1.2 0.4 0.7 4.1 0.1 2.7 0.0 0.5 6.3 2.3 0.5 1.0 3.2 0.7 0.5 0.5 0.9 0.5 0.8 0.6 0.6 0.8 9.4 3.2 0.0 0.0 2.3 0.3 4.8 1.8 2.2 0.7 3.6 2.9 0.7 2.8 3.5 0.0 4.2 0.9 6.9 1.0 0.0 0.1 170.7 0.2 0.6 2.7 0.0 1.7 0.2 0.2 2.3 0.9 0.5 0.1 0.0 0.8 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.3 2.4 145.2 1.2 1.8 1.8 0.0 0.3 4.3 11.3 0.0 0.0 0.3 0.1 0.7 7.6 3.3 0.0 0.3 0.8 1.7 6.6 0.6 2.9 3.6 2.8 1.7 1.0 0.4 14.8 0.3 0.4 1.3 NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.2;lymphoid tissue: 37.4;testis: 35.4" "Cell type enhanced" "Detected in many" "Plasma cells: 26.3;Spermatocytes: 89.3;Spermatogonia: 29.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.8;T-cells: 6.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Nucleoplasm "HPA002647: AB_1078300, HPA003008: AB_1078301" "unprognostic (5.52e-2)" "unprognostic (7.37e-2)" "unprognostic (2.93e-2)" "unprognostic (2.85e-3)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "prognostic unfavorable (9.53e-6)" "prognostic unfavorable (6.73e-4)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.16e-2)" "unprognostic (0.00e+0)" "unprognostic (3.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (2.30e-2)" 1.2 0.7 0.3 9.9 0.4 35.2 1.8 0.9 0.9 1.3 0.1 7.7 5.6 0.9 0.2 6.3 0.5 1.6 0.4 0.3 0.2 0.4 1.0 1.1 20.3 0.1 0.0 0.3 0.3 0.5 0.2 5.2 0.3 0.4 9.3 1.8 1.5 0.2 0.3 4.7 6.2 2.8 0.0 3.7 3.6 35.4 0.1 37.4 0.4 0.1 22.0 2.6 2.0 0.3 134.1 52.0 115.1 60.6 3.9 6.1 80.8 58.7 40.3 115.1 118.4 93.5 71.5 121.0 41.8 26.6 106.2 57.2 100.2 39.6 117.2 110.0 63.4 123.7 49.3 74.5 0.7 112.2 101.3 1.8 4.2 89.1 35.9 10.2 46.6 89.7 89.5 88.8 53.0 59.5 183.8 104.2 85.9 57.6 56.6 133.4 106.7 95.5 23.6 49.6 71.2 52.3 34.8 46.5 19.9 42.4 36.6 80.0 24.1 83.5 126.3 76.9 101.9 44.4 70.1 134.0 33.7 111.5 95.3 3.8 0.0 0.2 0.8 0.9 0.1 0.9 1.2 1.0 0.4 0.9 0.0 0.4 0.3 0.1 0.0 0.0 6.2 0.5 0.3 0.4 0.9 0.9 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 4.9 0.0 0.0 0.0 3.5 0.6 0.7 1.9 1.2 0.4 1.0 0.8 0.5 0.0 1.6 0.0 8.4 9.4 2.0 2.1 0.0 0.5 5.9 1.7 0.9 1.8 0.0 16.4 0.4 0.0 16.3 1.8 4.1 1.2 1.3 5.5 1.4 0.4 8.5 0.0 0.3 2.8 0.0 3.8 3.7 4.9 0.9 2.2 1.8 0.0 0.2 8.5 0.0 0.5 1.0 0.2 0.1 0.4 26.3 0.7 0.4 0.0 1.6 2.3 0.0 0.2 3.5 89.3 29.4 8.8 0.9 1.9 5.1 0.6 5.7 1.1 NEURL3 "Lincr, LOC93082, RNF132" ENSG00000163121 "Neuralized E3 ubiquitin protein ligase 3" Q96EH8 2 96497646-96508109 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 16.2;pancreas: 25.1;salivary gland: 30.3" "Group enriched" "Detected in many" 4 "Ductal cells: 114.6;Exocrine glandular cells: 36.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.8;CAPAN-2: 15.6;GAMG: 5.5;RPMI-8226: 10.1;RT4: 4.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (4.97e-2)" "unprognostic (6.07e-2)" "unprognostic (7.22e-2)" "unprognostic (1.42e-2)" "unprognostic (2.49e-2)" "unprognostic (4.35e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.29e-1)" "unprognostic (9.55e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-1)" "unprognostic (8.14e-3)" "unprognostic (1.23e-2)" "unprognostic (5.83e-2)" "unprognostic (6.57e-2)" "unprognostic (2.44e-1)" "unprognostic (6.57e-4)" 0.1 0.0 0.8 0.4 0.8 0.3 1.9 0.6 0.9 0.1 0.5 0.7 1.6 0.1 0.1 0.1 0.2 2.1 0.2 0.8 0.7 16.2 2.5 2.5 0.2 0.8 0.7 0.0 25.1 0.0 0.3 0.0 0.8 3.9 0.5 0.1 30.3 2.5 0.1 0.6 2.1 0.0 0.7 0.6 0.5 0.4 0.7 4.8 0.0 0.0 0.3 0.4 0.0 0.9 1.0 0.5 0.0 0.3 0.0 0.0 3.8 0.0 0.4 0.3 0.2 2.3 15.6 0.0 1.2 0.0 5.5 2.3 0.2 0.0 0.0 0.6 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 0.0 10.1 2.1 4.7 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.8 0.6 0.9 0.8 0.7 0.8 0.7 0.8 0.7 0.7 0.9 0.4 0.0 1.5 0.7 0.9 0.0 10.2 0.0 0.0 0.0 7.6 8.3 0.4 11.5 0.6 9.2 0.0 0.3 0.3 6.9 3.9 114.6 0.0 4.9 0.2 1.0 2.4 3.2 0.4 36.5 0.0 0.2 0.0 0.8 0.0 0.1 0.0 0.2 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 12.2 0.8 0.0 0.0 0.1 17.8 5.2 0.0 0.0 13.2 10.6 5.8 0.0 0.0 0.0 0.0 0.4 0.7 1.9 0.0 0.0 0.0 0.2 1.4 1.2 5.9 ARID5A "MRF-1, RP11-363D14" ENSG00000196843 "AT-rich interaction domain 5A" Q03989 2 96536743-96552634 "Predicted intracellular proteins, Transcription factors" "Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 137.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HDLM-2: 295.3;RPMI-8226: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002860, HPA023879" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Nucleoli "HPA002860: , HPA023879: AB_1845014" "prognostic favorable (2.05e-6)" "unprognostic (1.08e-3)" "unprognostic (1.69e-2)" "unprognostic (3.89e-3)" "unprognostic (1.90e-2)" "unprognostic (3.38e-2)" "unprognostic (3.03e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (2.46e-1)" "unprognostic (1.56e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.24e-8)" "unprognostic (2.74e-2)" "unprognostic (9.79e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-2)" 32.6 4.5 8.1 19.5 8.9 11.8 38.8 8.7 11.1 18.5 7.7 25.9 5.0 25.2 2.0 7.8 24.1 12.3 28.8 7.8 8.7 12.3 8.5 48.1 19.0 14.3 10.8 10.8 6.9 2.2 9.3 9.6 11.5 23.2 2.3 2.2 10.2 2.6 23.5 11.3 19.8 7.3 10.6 22.8 14.6 5.6 10.2 10.3 13.0 2.3 9.9 19.9 15.4 9.6 3.4 1.9 1.6 5.4 2.7 3.0 7.5 5.1 17.2 6.1 5.3 3.1 0.9 1.1 3.8 2.9 9.1 4.6 1.4 0.3 2.1 295.3 4.1 6.9 1.1 5.8 3.4 4.7 4.9 2.1 5.7 5.0 0.9 5.3 5.4 8.1 5.4 38.5 2.4 2.9 8.7 16.1 3.3 1.5 0.2 12.2 11.3 117.5 0.7 2.5 2.2 1.1 0.5 0.6 4.3 1.3 0.2 10.0 6.0 5.4 6.7 6.2 4.6 24.7 21.5 3.1 3.0 11.1 4.9 10.5 7.9 32.8 15.3 6.9 14.9 5.9 13.1 14.6 10.3 6.5 14.1 14.4 21.5 27.5 5.5 18.4 16.0 14.9 8.1 8.9 8.7 11.1 7.8 8.7 14.3 10.8 11.5 10.6 10.2 9.6 97.1 3.2 18.3 3.9 59.9 52.4 46.5 17.0 5.7 24.8 80.3 44.7 14.7 8.6 14.7 3.7 31.3 4.9 121.1 10.8 3.9 33.7 14.2 16.7 26.8 82.2 0.0 3.4 1.5 30.9 9.0 41.2 11.2 32.4 61.9 2.1 38.6 28.7 72.6 0.0 1.6 10.7 20.3 41.5 137.1 36.7 3.7 61.6 58.7 15.9 66.6 6.5 123.6 3.5 1.3 29.1 23.9 6.4 54.5 28.2 0.6 10.6 8.3 25.7 46.0 49.1 120.1 3.2 17.9 1.1 32.5 4.0 98.2 2.1 7.8 26.9 KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035017, HPA035018" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Vesicles "HPA035017: AB_2674414, HPA035018: AB_10601763" "unprognostic (2.19e-1)" "unprognostic (6.94e-2)" "unprognostic (5.62e-2)" "unprognostic (8.72e-3)" "unprognostic (3.28e-1)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.01e-2)" "unprognostic (2.99e-2)" "unprognostic (2.04e-3)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-3)" "unprognostic (4.99e-3)" 11.8 9.9 1.9 8.6 2.4 14.9 12.3 1.6 3.1 13.7 8.1 11.8 7.2 15.0 7.7 8.9 12.5 6.9 10.7 2.9 2.6 8.8 6.4 9.9 8.2 2.1 2.9 15.1 9.8 15.1 8.8 9.0 2.3 11.2 6.9 6.3 12.5 14.7 33.9 10.8 12.0 10.6 3.3 10.1 9.8 12.8 3.3 13.1 12.9 21.1 8.9 13.0 10.8 2.3 13.1 7.9 26.0 19.4 10.6 6.4 11.4 9.7 15.2 20.1 21.4 15.1 7.8 18.1 14.6 16.2 14.7 8.2 18.8 9.4 17.5 12.8 14.8 26.0 8.1 16.2 15.0 17.4 9.0 15.0 5.8 12.8 11.4 12.0 11.0 21.0 18.6 12.8 12.8 6.9 32.3 13.5 12.5 6.7 12.8 26.2 16.5 10.6 12.4 12.7 26.8 16.9 12.3 11.8 11.8 14.7 11.4 5.5 15.9 13.5 11.8 9.8 8.9 10.1 6.7 15.7 7.0 19.9 12.2 2.4 1.3 0.5 2.8 1.5 2.1 1.6 1.7 2.9 0.7 1.5 1.2 2.3 0.2 3.1 1.3 0.7 1.1 1.7 1.9 2.4 1.6 3.1 2.9 2.6 2.1 2.9 2.3 3.3 3.3 2.3 11.6 44.8 30.8 29.0 10.5 4.6 9.9 8.1 9.1 15.0 14.8 12.2 23.8 10.0 18.8 11.0 43.8 8.1 10.0 15.0 3.9 10.5 13.4 13.0 13.7 12.1 13.1 6.7 35.6 9.6 4.3 12.7 17.3 13.5 18.3 33.1 15.7 12.7 8.1 15.2 36.2 18.4 10.2 12.5 5.6 28.6 9.9 11.2 7.2 16.9 13.7 10.2 9.2 29.7 37.3 13.2 7.9 12.8 10.6 10.3 10.7 5.8 13.1 29.5 13.1 16.0 13.6 23.3 9.7 11.3 6.5 11.1 14.2 18.3 15.6 10.1 FER1L5 DKFZp434I0121 ENSG00000249715 "Fer-1 like family member 5" A0AVI2 2 96642737-96704887 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 1.7;testis: 4.1" "Cell type enhanced" "Detected in some" "Astrocytes: 4.9;Early spermatids: 22.7;Excitatory neurons: 5.5;Late spermatids: 6.9;Spermatocytes: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.11e-2)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (3.34e-3)" "unprognostic (5.81e-3)" "unprognostic (2.06e-1)" "unprognostic (1.12e-4)" "unprognostic (4.49e-4)" "unprognostic (1.39e-2)" "unprognostic (6.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (2.95e-2)" "unprognostic (2.68e-2)" "unprognostic (2.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.16e-3)" 0.0 0.0 0.3 0.0 0.9 0.0 0.3 0.4 0.3 0.0 1.7 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.0 0.2 0.7 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.4 0.3 0.4 0.3 0.2 0.7 0.2 0.0 0.2 0.1 0.1 3.2 1.1 4.9 0.5 0.0 1.1 0.0 0.0 0.3 0.7 0.3 1.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.5 22.7 0.1 0.5 0.2 0.0 0.0 5.5 0.6 0.0 0.3 0.0 0.1 1.3 0.1 1.1 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 6.9 0.3 0.1 0.0 0.0 0.0 0.7 0.0 0.5 0.3 0.1 0.0 0.4 0.1 0.6 0.0 0.1 1.5 0.1 0.0 0.4 0.2 4.3 1.4 0.0 0.0 0.3 0.2 1.3 0.0 0.4 LMAN2L "DKFZp564L2423, VIPL" ENSG00000114988 "Lectin, mannose binding 2 like" Q9H0V9 2 96705929-96740064 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026600 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA026600: AB_1852939" "unprognostic (3.02e-1)" "unprognostic (2.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-2)" "unprognostic (4.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" "unprognostic (6.91e-3)" "unprognostic (1.16e-1)" "unprognostic (5.30e-2)" "unprognostic (8.14e-2)" "unprognostic (2.17e-1)" "unprognostic (1.52e-1)" "unprognostic (3.29e-1)" 10.1 11.0 16.5 4.9 17.4 1.3 12.2 16.6 20.0 15.8 15.9 14.4 5.6 13.8 17.2 9.5 17.1 6.7 19.2 16.6 21.9 17.9 18.1 9.8 5.9 18.1 17.7 21.1 11.9 13.7 17.3 11.6 17.9 15.0 10.6 7.7 10.9 13.6 16.7 11.0 8.2 15.6 16.7 8.6 10.8 11.2 22.9 9.1 15.5 19.1 7.1 13.2 12.5 17.2 21.1 33.3 25.6 26.6 31.9 15.1 23.4 19.3 23.9 39.9 43.5 57.4 15.7 10.2 71.4 47.8 99.2 25.1 36.9 30.2 50.2 27.1 20.4 8.9 21.4 49.0 20.1 15.3 14.3 17.4 28.2 30.5 9.6 34.7 23.7 17.2 20.3 20.5 25.5 14.5 11.0 14.5 13.9 14.9 36.0 23.1 21.1 11.6 32.9 10.9 16.2 8.5 21.8 16.6 20.1 46.8 19.8 26.4 17.3 31.8 22.7 25.1 25.9 13.3 46.1 8.6 18.8 18.1 26.3 37.8 17.5 22.4 14.0 10.6 32.0 20.0 16.2 18.9 14.5 16.9 19.6 16.6 9.5 15.9 16.0 20.8 14.8 18.5 16.5 17.4 16.6 20.0 16.6 21.9 18.1 17.7 17.9 16.7 22.9 17.2 4.7 12.8 6.8 12.4 3.2 3.4 5.4 11.1 2.2 3.1 10.5 7.6 12.2 5.7 6.3 12.9 6.2 17.9 5.2 5.4 9.8 13.7 20.6 4.6 6.9 6.1 9.5 6.5 13.4 7.8 10.4 11.8 2.0 5.6 5.1 16.8 9.3 10.7 9.9 1.7 13.4 5.0 0.0 5.6 1.4 18.0 6.8 2.7 3.6 7.5 12.3 12.2 6.2 11.1 11.0 7.5 3.8 8.6 3.1 4.5 4.6 10.1 6.3 5.1 13.1 4.4 8.1 13.3 14.0 2.5 2.7 13.4 4.0 8.6 6.5 2.1 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNNM3 ACDP3 ENSG00000168763 "Cyclin and CBS domain divalent metal cation transport mediator 3" Q8NE01 2 96816245-96835382 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 33.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016711 Supported Approved Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA016711: AB_1847394" "unprognostic (1.50e-2)" "unprognostic (6.96e-2)" "unprognostic (2.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-1)" "unprognostic (3.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.32e-3)" "unprognostic (3.64e-1)" "unprognostic (5.31e-3)" "unprognostic (7.35e-2)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" 7.8 8.9 8.0 6.7 10.1 7.0 7.9 15.0 9.5 8.4 8.0 10.5 17.3 8.5 5.2 5.6 10.9 9.4 5.7 7.5 7.1 7.5 20.0 9.1 9.1 9.2 9.0 10.3 26.6 21.4 8.0 10.2 8.5 8.9 8.8 13.1 12.4 9.0 45.1 8.5 14.2 5.8 6.9 9.5 12.4 11.3 8.6 11.4 8.4 6.1 7.2 8.3 7.6 12.5 10.4 9.2 8.7 13.4 10.2 5.4 24.3 6.8 5.5 6.4 6.3 25.3 16.4 11.7 23.3 5.2 7.4 11.8 12.6 8.8 4.8 11.3 29.4 15.3 12.9 28.1 8.9 14.0 11.2 4.5 11.8 8.1 7.3 8.7 7.9 9.6 14.1 19.8 2.7 13.0 12.8 17.4 11.6 15.6 11.5 15.6 11.6 14.4 11.3 12.7 26.5 17.0 8.7 14.2 8.2 13.3 13.5 10.2 3.7 5.6 16.1 9.2 9.8 17.8 18.1 8.6 3.5 13.2 6.0 1.6 0.8 3.5 2.6 0.6 1.6 1.8 1.6 2.1 0.3 2.1 1.5 1.5 3.3 1.5 1.4 1.8 2.2 0.8 8.0 10.1 15.0 9.5 7.5 7.1 9.2 9.0 8.5 6.9 8.6 12.5 4.1 9.6 4.8 9.1 5.4 1.3 2.7 1.1 0.6 17.5 4.9 5.0 15.6 8.6 3.0 0.0 8.4 5.0 8.9 4.7 0.0 5.0 7.3 5.3 4.4 3.7 4.2 5.7 5.7 4.3 2.6 4.3 5.6 12.6 0.0 11.7 6.4 17.4 2.6 33.7 9.5 7.6 4.1 3.4 0.6 1.3 2.5 1.9 3.6 4.7 2.3 6.4 6.2 18.1 19.6 2.7 1.9 4.1 6.4 7.1 8.4 1.9 2.8 13.5 13.1 5.7 4.5 5.9 6.3 2.8 1.6 1.6 6.9 11.5 8.2 3.4 ANKRD23 "DARP, FLJ32449, MARP3" ENSG00000163126 "Ankyrin repeat domain 23" Q86SG2 2 96824526-96857934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "skeletal muscle: 1438.6;tongue: 448.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 5.0;Respiratory ciliated cells: 7.4;Rod photoreceptor cells: 5.2;Skeletal myocytes: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "Karpas-707: 38.5" "Low region specificity" "Detected in many" HPA036201 Approved Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Actin filaments" "HPA036201: AB_10673347" "unprognostic (2.48e-1)" "unprognostic (7.83e-4)" "unprognostic (4.93e-4)" "unprognostic (1.21e-2)" "unprognostic (4.28e-1)" "unprognostic (3.28e-1)" "unprognostic (3.27e-2)" "unprognostic (6.66e-2)" "unprognostic (2.46e-2)" "unprognostic (3.59e-2)" "unprognostic (1.81e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-6)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.54e-1)" "unprognostic (2.70e-4)" 0.8 0.9 1.6 0.4 2.1 0.7 1.2 2.2 2.1 1.4 0.6 1.3 0.8 1.8 0.0 6.0 2.5 0.2 24.2 1.5 1.4 0.7 2.2 1.0 0.6 2.5 1.6 1.7 1.6 0.3 10.4 0.2 1.8 5.3 0.1 0.1 18.5 0.3 1438.6 2.5 1.3 0.2 1.5 2.3 0.7 0.7 1.9 0.6 1.1 448.6 0.4 1.2 1.1 2.3 0.5 0.7 0.4 0.8 0.0 0.2 1.1 0.3 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.3 0.3 0.2 1.1 1.0 0.5 0.8 0.2 0.1 0.8 1.8 0.3 0.3 0.6 0.0 0.2 0.1 1.5 0.9 38.5 0.3 0.9 0.5 0.8 0.4 0.1 0.3 1.4 0.0 5.0 0.2 0.9 1.4 0.2 0.3 0.7 0.0 0.2 1.1 0.0 0.3 0.5 0.6 0.7 0.1 1.7 0.7 0.3 0.4 1.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 2.1 2.2 2.1 1.5 1.4 2.5 1.6 1.8 1.5 1.9 2.3 1.1 0.0 1.1 2.0 0.5 0.8 0.5 0.4 0.6 2.6 0.8 2.3 5.0 0.0 1.5 0.0 2.1 0.4 2.1 0.9 0.0 0.3 3.3 1.3 1.9 0.8 0.0 0.4 2.8 1.1 0.2 1.3 0.5 0.7 1.3 1.1 1.4 1.2 0.2 1.7 2.7 1.0 0.0 0.6 0.3 1.8 1.5 0.6 0.0 1.0 0.2 1.1 1.0 0.5 2.9 0.1 0.3 3.0 0.4 0.3 0.6 0.2 7.4 5.2 0.0 6.1 1.6 1.3 0.4 0.4 1.3 0.3 1.1 0.7 0.9 0.2 ANKRD39 MGC41816 ENSG00000213337 "Ankyrin repeat domain 39" Q53RE8 2 96836611-96858016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 263.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042678 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Vesicles "HPA042678: AB_10794532" "unprognostic (6.26e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (9.53e-2)" "unprognostic (2.28e-2)" "unprognostic (2.09e-1)" "unprognostic (4.03e-2)" "unprognostic (1.68e-1)" "unprognostic (9.25e-2)" "unprognostic (3.12e-3)" "prognostic favorable (6.12e-5)" "unprognostic (6.15e-2)" "prognostic unfavorable (6.78e-9)" "unprognostic (3.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.03e-2)" "prognostic favorable (5.21e-4)" 6.8 14.1 13.1 7.2 13.4 10.5 7.3 15.9 18.7 6.9 8.9 11.0 8.3 10.2 2.9 7.5 10.2 5.9 14.9 13.2 13.2 7.9 14.8 6.2 11.0 13.0 12.5 6.6 8.3 12.3 16.0 5.5 13.4 8.2 4.0 5.3 7.4 6.8 7.9 8.7 7.4 6.2 12.3 9.7 8.3 4.1 12.5 7.4 5.8 4.5 6.5 8.5 6.8 14.5 24.0 15.7 8.8 19.2 2.9 5.7 21.1 18.1 8.4 22.5 17.3 38.8 9.9 15.2 26.4 13.2 17.7 10.3 11.2 17.3 5.0 17.6 34.1 11.0 14.4 53.5 14.8 24.9 25.6 11.0 10.2 20.5 7.9 8.4 16.3 31.1 23.5 263.1 8.4 37.9 23.3 19.5 11.1 8.1 35.8 17.8 6.2 85.3 11.8 12.3 20.3 13.3 13.1 30.6 23.7 8.0 9.3 13.5 8.2 14.0 13.8 16.0 32.5 13.4 16.2 25.3 14.0 28.5 14.9 20.1 16.0 13.4 44.4 20.8 37.7 41.6 43.6 39.3 16.6 33.2 24.0 29.2 8.3 37.6 23.5 70.4 71.0 21.1 13.1 13.4 15.9 18.7 13.2 13.2 13.0 12.5 13.4 12.3 12.5 14.5 14.0 6.4 8.9 2.6 16.9 9.4 17.2 25.7 9.1 25.2 14.9 23.2 19.5 18.6 17.6 9.2 4.2 44.9 28.1 15.1 25.4 28.8 6.1 18.1 18.7 12.9 18.6 13.5 4.6 32.0 38.6 14.9 11.7 11.8 12.7 12.7 10.8 32.0 31.6 33.7 5.3 19.9 18.3 11.1 10.4 2.9 12.5 13.8 28.4 1.0 9.3 15.9 37.0 4.5 5.9 41.3 11.3 14.7 26.2 12.5 23.4 29.4 35.0 29.8 26.3 24.9 18.8 13.6 14.3 18.9 17.8 21.6 24.4 33.5 16.9 15.7 SEMA4C "Semacl1, Semaf, SEMAI" ENSG00000168758 "Semaphorin 4C" Q9C0C4 2 96859718-96870757 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 137.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "BEWO: 298.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011090 Approved NA NA 700000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA011090: AB_2185705" "unprognostic (1.25e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.53e-5)" "unprognostic (7.10e-2)" "unprognostic (4.46e-2)" "unprognostic (1.57e-2)" "unprognostic (4.20e-3)" "unprognostic (3.08e-1)" "unprognostic (2.16e-1)" "unprognostic (3.56e-2)" "unprognostic (1.82e-1)" "unprognostic (3.57e-1)" "prognostic unfavorable (9.50e-7)" "unprognostic (4.78e-3)" "unprognostic (3.09e-1)" "unprognostic (7.31e-2)" "unprognostic (4.08e-1)" 21.3 8.9 11.5 11.3 24.2 3.0 17.7 16.8 19.9 29.0 0.5 42.1 7.4 37.2 6.0 14.0 33.3 15.3 20.2 11.8 15.6 14.9 13.3 14.4 9.8 24.9 21.1 23.1 9.4 7.1 10.2 41.8 21.0 20.8 5.7 7.0 16.5 20.6 7.5 15.9 14.6 19.3 18.7 28.5 15.1 2.7 19.0 6.5 12.3 13.4 5.3 32.3 22.3 39.1 8.0 11.7 35.6 39.7 8.4 10.5 298.5 13.9 17.4 13.4 13.5 11.8 13.3 0.0 22.3 8.5 13.3 8.1 10.2 6.9 6.5 15.2 11.8 5.4 10.5 22.2 19.2 2.2 13.7 16.1 5.4 12.3 10.4 14.9 9.9 2.6 36.5 11.6 12.7 41.0 0.1 17.4 49.1 0.4 10.6 12.5 20.0 13.8 4.8 17.1 22.4 32.4 11.2 24.6 60.8 27.6 8.7 21.4 3.1 21.9 27.3 30.9 14.6 0.2 1.0 0.1 10.6 17.2 37.1 0.5 0.0 0.0 0.6 0.2 0.8 0.0 0.2 0.4 0.0 0.0 0.4 0.1 0.0 1.4 1.5 0.8 0.3 0.4 11.5 24.2 16.8 19.9 11.8 15.6 24.9 21.1 21.0 18.7 19.0 39.1 28.1 0.0 10.3 15.3 1.1 11.5 7.9 7.6 18.2 32.2 9.9 8.3 6.9 12.8 8.6 5.5 10.4 46.8 9.7 1.8 1.9 9.7 0.5 7.4 15.8 26.6 5.4 2.1 7.2 5.0 137.3 17.3 3.1 11.6 1.3 10.2 23.9 9.8 7.9 15.2 4.1 5.7 6.1 4.4 6.1 1.5 13.4 9.2 21.4 18.7 3.2 23.6 12.3 4.5 35.5 10.5 1.2 9.1 3.6 9.4 0.1 0.8 7.4 38.8 19.7 11.4 24.1 0.6 4.2 13.0 10.2 45.0 9.5 4.9 3.9 4.8 FAM178B LOC51252 ENSG00000168754 "Family with sequence similarity 178 member B" Q8IXR5 2 96875882-96986580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 18.9;brain: 10.5;epididymis: 5.5;lymphoid tissue: 12.1;testis: 8.2" "Cell type enriched" "Detected in many" 4 "Erythroid cells: 88.3" "Cancer enriched" "Detected in many" 5 "melanoma: 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 25.7;OE19: 7.0;RPMI-8226: 28.0;WM-115: 27.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 2.4" "HPA042516, HPA062110" Uncertain Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 33: Fibroblasts - ECM organization" "Nuclear speckles" "Golgi apparatus" "HPA042516: AB_10806241, HPA062110: " "unprognostic (2.47e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" "unprognostic (8.04e-4)" "unprognostic (1.39e-1)" "unprognostic (1.28e-2)" "unprognostic (9.02e-4)" "unprognostic (4.70e-2)" "unprognostic (8.55e-2)" "unprognostic (6.49e-3)" "unprognostic (1.49e-1)" "unprognostic (5.13e-2)" "unprognostic (9.82e-11)" "unprognostic (6.93e-2)" "unprognostic (1.57e-1)" "unprognostic (9.63e-3)" "unprognostic (1.08e-1)" 1.7 0.0 4.9 0.0 8.7 18.9 0.9 6.3 7.3 0.5 2.3 2.2 0.0 1.6 5.5 0.7 1.3 0.1 0.4 4.7 6.8 0.1 0.0 0.4 0.1 7.7 8.0 0.5 0.0 0.0 0.1 0.9 7.4 1.1 0.1 0.1 0.3 0.8 0.2 1.2 0.5 0.4 6.5 12.1 0.3 8.2 7.3 0.1 0.1 0.0 0.0 2.1 0.8 10.5 6.2 0.0 0.0 2.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.5 2.5 0.0 0.0 0.2 7.0 0.0 0.0 6.7 28.0 0.0 0.0 0.8 0.0 0.0 4.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 27.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 0.1 4.9 8.7 6.3 7.3 4.7 6.8 7.7 8.0 7.4 6.5 7.3 10.5 0.2 0.0 0.0 1.0 1.2 0.8 0.6 0.4 0.0 0.2 0.5 1.4 0.4 0.0 0.0 0.0 2.1 3.2 0.5 0.1 0.0 0.0 3.6 0.1 0.3 0.2 0.0 88.3 7.2 0.0 7.1 3.0 0.0 0.1 0.0 0.2 0.4 0.0 1.2 1.7 1.1 0.0 10.2 0.0 0.9 7.8 0.9 1.0 3.6 1.0 0.2 2.9 1.0 1.0 20.7 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.2 0.0 2.8 1.6 3.2 20.1 0.6 1.7 2.5 0.2 0.3 0.1 0.4 FAHD2B DKFZp434N062 ENSG00000144199 "Fumarylacetoacetate hydrolase domain containing 2B" Q6P2I3 2 97083583-97094882 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 235.0;Late spermatids: 212.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 8.8;NK-cells: 16.2;T-cells: 15.5" "Low cell line specificity" "Detected in many" "HPA042145, HPA044987" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "HPA042145: AB_2677873, HPA044987: AB_2679170" "unprognostic (6.55e-3)" "unprognostic (5.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.03e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (9.03e-3)" "unprognostic (4.13e-3)" "unprognostic (8.84e-3)" "unprognostic (1.59e-1)" "unprognostic (1.41e-1)" "unprognostic (8.65e-3)" "unprognostic (1.94e-1)" "unprognostic (7.67e-2)" "unprognostic (1.48e-1)" "unprognostic (5.03e-2)" "unprognostic (6.26e-3)" "unprognostic (2.04e-1)" 10.7 7.1 24.5 3.2 28.2 3.5 12.8 29.5 25.2 16.6 21.1 14.5 2.5 17.6 38.1 7.4 17.2 4.2 30.0 23.7 28.8 12.6 4.0 7.9 5.7 27.8 25.8 23.6 14.4 11.1 10.3 1.7 28.9 10.9 5.5 6.8 10.8 6.8 30.3 13.6 8.2 11.2 29.6 6.8 24.7 46.8 28.6 4.2 3.9 45.9 7.7 14.3 12.2 33.1 5.0 6.0 8.2 16.8 8.0 9.5 13.0 4.3 5.0 7.3 6.7 5.6 7.7 9.6 3.7 1.7 13.7 5.2 12.0 9.6 4.1 12.5 22.1 10.5 7.6 4.5 25.6 11.9 6.5 12.8 10.0 0.9 15.5 3.4 7.8 37.0 18.3 22.9 0.5 0.0 14.5 35.5 8.1 2.2 16.7 14.0 2.3 34.5 8.1 8.3 1.8 7.1 14.7 3.8 21.5 15.3 16.1 9.4 1.3 0.8 13.7 1.0 4.2 15.1 21.1 25.4 1.2 30.5 10.1 0.0 0.2 0.2 11.3 0.3 15.5 8.8 11.0 11.1 1.8 4.2 7.5 9.7 0.2 16.2 0.1 2.9 15.0 4.8 24.5 28.2 29.5 25.2 23.7 28.8 27.8 25.8 28.9 29.6 28.6 33.1 8.2 6.4 11.1 11.1 6.1 6.5 11.5 5.9 9.6 6.3 17.9 21.0 42.3 4.3 8.0 5.5 2.1 2.1 5.8 1.1 27.4 7.3 235.0 2.3 6.5 7.8 1.8 5.5 10.4 4.3 1.0 13.5 30.1 1.2 5.7 18.5 8.2 2.3 3.5 5.0 12.1 3.3 6.1 1.6 2.6 212.6 17.1 2.2 30.2 2.8 1.6 21.7 9.2 2.5 8.0 6.9 1.2 17.0 17.3 7.7 0.2 3.8 4.6 5.8 0.0 9.7 10.5 24.5 7.3 7.3 7.1 1.0 8.2 11.1 4.4 8.3 ANKRD36 UNQ2430 ENSG00000135976 "Ankyrin repeat domain 36" A6QL64 2 97113153-97264521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.0;retina: 20.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 240.8;Inhibitory neurons: 255.3;Oligodendrocyte precursor cells: 155.3;Oligodendrocytes: 217.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA051757: AB_2681594, HPA057661: AB_2683494" "unprognostic (4.24e-3)" "unprognostic (7.59e-2)" "unprognostic (6.15e-3)" "unprognostic (9.86e-2)" "unprognostic (9.83e-3)" "unprognostic (5.25e-3)" "unprognostic (5.65e-2)" "unprognostic (1.49e-2)" "unprognostic (4.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.00e-1)" "unprognostic (2.51e-2)" "unprognostic (9.14e-7)" "unprognostic (1.67e-2)" "unprognostic (2.23e-1)" "unprognostic (2.64e-2)" "unprognostic (1.75e-1)" 1.8 1.6 5.8 2.7 8.3 11.8 3.2 25.0 7.8 2.2 0.3 1.8 1.8 3.6 4.2 1.0 2.1 1.9 1.3 5.3 4.0 0.9 0.6 2.4 2.9 7.1 2.0 4.5 1.8 1.8 1.9 1.3 8.2 2.3 2.6 20.3 2.1 1.4 0.7 3.2 1.8 2.3 1.5 3.3 2.8 7.1 6.2 3.1 2.1 0.5 2.2 1.4 1.8 9.5 4.4 1.4 3.9 2.4 0.9 2.1 1.5 2.1 1.3 1.5 1.5 1.3 2.3 5.5 1.0 1.4 1.2 2.9 1.4 1.9 1.3 2.9 2.4 4.7 6.4 2.4 0.4 3.8 1.9 1.4 0.9 1.2 1.9 2.2 2.9 8.9 3.6 10.1 0.8 1.0 4.4 4.4 0.9 0.4 2.8 5.0 1.9 2.2 0.8 2.3 3.3 2.2 2.3 1.3 0.7 1.5 1.4 1.9 3.9 4.2 3.8 4.1 2.3 6.5 2.8 5.1 2.2 4.5 1.0 9.2 2.2 3.1 7.2 1.0 7.4 9.2 7.1 6.1 0.9 8.1 7.2 7.5 3.3 4.9 2.3 10.1 6.6 2.0 5.8 8.3 25.0 7.8 5.3 4.0 7.1 2.0 8.2 1.5 6.2 9.5 16.9 44.8 27.4 85.5 27.8 15.7 8.4 28.2 14.2 51.0 9.0 11.2 26.2 2.8 31.5 7.3 75.0 1.4 38.2 4.9 0.0 7.1 70.7 39.6 22.2 19.3 13.8 14.3 240.8 18.6 5.6 19.5 84.6 19.3 26.6 39.4 11.7 1.1 5.1 21.9 255.3 10.5 12.2 3.8 26.2 14.3 26.1 10.2 39.2 46.9 6.1 9.3 26.8 155.3 217.7 9.5 3.6 18.0 56.3 5.9 2.2 2.7 43.2 65.0 0.0 36.4 20.7 123.4 22.1 9.8 9.2 0.4 39.6 9.1 8.1 14.1 ANKRD36B "FLJ21281, KIAA1641" ENSG00000196912 "Ankyrin repeat domain 36B" Q8N2N9 2 97492663-97589965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.5" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 73.4;Oligodendrocytes: 71.1;Plasma cells: 81.7;Spermatocytes: 76.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA051757: AB_2681594, HPA057661: AB_2683494" "unprognostic (2.07e-1)" "unprognostic (9.96e-2)" "unprognostic (1.53e-1)" "unprognostic (2.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-1)" "unprognostic (8.72e-3)" "unprognostic (5.03e-2)" "unprognostic (7.17e-3)" "unprognostic (4.20e-2)" "unprognostic (4.00e-2)" "unprognostic (2.13e-6)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (7.71e-3)" "unprognostic (6.98e-2)" 4.4 1.8 3.0 1.6 4.8 21.5 4.7 13.7 5.8 4.7 0.0 3.2 1.0 4.1 2.3 1.8 5.0 1.7 2.7 3.1 2.5 2.4 1.1 3.0 2.6 4.7 1.2 5.3 6.1 1.0 2.9 0.8 5.3 3.4 2.8 10.1 4.3 1.4 1.3 4.1 3.5 2.8 1.0 3.1 3.2 13.1 4.1 2.9 2.7 0.2 1.9 3.1 3.1 7.2 2.9 1.4 1.4 1.7 1.1 2.8 1.8 1.5 1.2 1.0 1.1 1.8 3.2 4.7 1.1 1.5 1.0 0.4 1.1 1.1 1.1 1.5 2.2 3.6 3.5 1.3 0.8 2.6 1.6 1.5 1.5 1.5 2.4 2.8 1.4 7.1 3.8 5.0 1.2 0.5 3.0 3.3 0.9 0.5 1.4 3.2 0.6 0.7 1.4 2.1 1.8 2.3 1.2 0.7 0.9 3.1 1.6 2.0 2.6 1.5 1.8 2.5 2.8 3.9 5.7 3.3 1.9 3.9 1.3 1.9 0.1 0.2 0.6 0.1 0.6 0.6 0.8 0.5 0.1 1.0 0.9 0.6 0.1 0.8 0.0 0.8 0.4 0.1 3.0 4.8 13.7 5.8 3.1 2.5 4.7 1.2 5.3 1.0 4.1 7.2 14.6 12.8 15.0 27.1 28.3 0.0 6.9 0.0 20.5 36.7 5.4 7.4 15.4 5.7 17.3 9.2 20.9 1.4 15.4 5.9 0.0 9.4 48.9 29.6 10.1 12.5 14.4 16.4 68.5 14.0 3.9 11.4 73.4 14.1 22.8 23.4 4.2 0.7 3.4 16.8 68.7 12.6 0.0 1.2 0.0 7.3 12.8 9.5 0.0 19.7 7.3 6.8 12.3 42.3 71.1 9.7 3.6 7.5 81.7 5.0 2.5 1.3 16.8 34.1 6.6 25.2 9.9 76.4 11.1 24.0 0.0 0.1 35.2 7.1 6.7 12.4 COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1151.3;skeletal muscle: 1332.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 3614.3;Distal tubular cells: 3621.5;Proximal enterocytes: 2795.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034517 Supported Enhanced Mitochondria NA NA 230000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034517: AB_10603561" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (1.92e-2)" "unprognostic (2.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (2.72e-2)" "unprognostic (1.79e-2)" "unprognostic (4.20e-2)" "unprognostic (4.02e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.73e-4)" 209.1 252.9 323.0 42.8 339.7 113.3 178.7 373.1 436.0 138.1 349.2 322.6 164.2 124.6 72.3 284.6 136.9 32.6 1151.3 319.2 357.2 478.6 372.8 120.4 40.3 341.7 339.9 138.4 165.6 234.0 169.0 47.1 339.9 158.2 113.4 74.5 196.7 90.1 1332.7 213.2 211.9 51.1 332.9 153.2 290.6 101.2 353.1 64.4 185.0 705.9 54.3 179.8 179.1 355.3 144.9 165.5 106.8 169.7 115.9 105.8 428.3 180.0 100.8 118.3 130.5 459.9 148.7 240.8 377.3 116.5 188.4 217.9 117.5 181.8 56.4 188.7 493.2 324.2 166.6 559.8 220.3 310.6 231.2 193.8 161.6 113.4 91.2 125.4 104.4 187.8 243.6 115.5 94.0 360.0 203.5 450.0 196.6 257.2 854.3 194.9 170.6 368.8 167.5 227.9 202.2 210.3 175.0 225.0 374.8 146.0 115.7 345.5 186.9 107.5 181.4 174.4 118.7 265.8 274.7 183.1 194.9 264.5 113.5 1086.6 1062.7 933.1 458.0 1057.0 445.1 801.5 547.4 481.8 990.1 666.0 528.0 468.8 1016.6 469.6 926.3 677.6 783.4 1543.0 323.0 339.7 373.1 436.0 319.2 357.2 341.7 339.9 339.9 332.9 353.1 355.3 461.0 221.2 256.0 33.3 292.7 386.6 629.5 1166.0 377.9 239.1 433.2 536.2 3614.3 567.6 618.5 800.0 227.2 736.0 257.4 1960.0 3621.5 599.5 207.5 399.4 300.8 380.0 740.3 308.8 27.3 604.1 897.1 391.6 616.7 439.7 330.6 392.2 361.3 1234.9 875.0 141.3 33.7 1430.5 1043.6 485.2 651.9 360.8 351.6 456.6 912.4 30.0 711.7 461.5 314.1 15.6 39.4 505.4 1836.0 304.6 353.3 468.2 2795.9 2663.5 485.4 386.3 447.0 340.2 569.9 265.2 310.7 944.2 479.9 613.2 291.9 455.7 1576.9 915.9 ACTR1B "Arp1B, CTRN2" ENSG00000115073 "Actin related protein 1B" P42025 2 97655939-97664044 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047443 Approved Microtubules NA NA 49000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Microtubules "HPA047443: AB_2680049" "unprognostic (5.26e-2)" "unprognostic (8.91e-3)" "unprognostic (2.83e-3)" "unprognostic (2.67e-1)" "unprognostic (2.96e-1)" "unprognostic (2.82e-1)" "unprognostic (3.68e-3)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (7.84e-2)" "unprognostic (8.21e-2)" "unprognostic (6.29e-2)" "unprognostic (3.42e-2)" "unprognostic (2.78e-1)" "unprognostic (2.89e-2)" "unprognostic (4.58e-2)" "prognostic favorable (4.69e-4)" 38.5 68.3 60.0 24.9 61.0 38.8 41.9 54.1 66.4 41.1 59.3 52.1 36.1 48.1 21.5 37.5 43.4 26.0 68.6 60.6 57.0 47.0 54.3 36.7 30.9 57.3 55.2 47.1 72.9 51.1 41.4 20.6 58.4 43.6 22.1 22.0 45.4 37.3 86.9 39.3 43.2 26.5 56.6 57.8 52.1 20.8 58.2 33.2 45.8 68.8 24.8 44.0 36.4 57.7 52.8 28.5 27.1 35.8 49.1 39.8 78.1 49.2 74.2 34.6 28.9 22.5 28.1 38.0 45.3 50.5 37.1 28.4 21.9 56.5 14.6 76.6 36.8 28.2 28.3 62.1 38.3 22.8 43.1 39.7 41.5 22.0 67.7 51.8 39.0 46.8 20.1 44.8 52.1 58.5 44.2 28.6 27.5 40.1 38.1 24.7 39.6 63.2 55.0 41.1 31.7 23.8 23.7 48.1 36.2 34.8 38.1 35.9 41.1 23.0 35.6 24.7 20.8 57.7 27.0 13.7 68.8 32.5 21.1 11.7 15.0 19.2 19.1 13.5 14.6 14.6 20.9 19.2 21.1 14.7 17.2 18.8 5.7 14.9 20.5 8.5 29.7 16.4 60.0 61.0 54.1 66.4 60.6 57.0 57.3 55.2 58.4 56.6 58.2 57.7 43.8 19.2 18.2 15.0 30.4 13.6 30.9 28.4 16.5 38.5 24.9 20.8 32.8 22.8 22.2 22.0 12.5 29.0 26.1 26.5 35.2 69.2 13.2 16.2 16.4 30.9 25.8 24.6 33.4 58.0 57.7 24.3 23.4 13.1 29.9 20.4 28.2 18.7 29.1 55.5 26.4 31.7 36.7 18.5 20.0 10.0 24.2 17.4 23.2 12.2 57.3 29.5 43.3 17.1 26.1 42.8 32.8 26.7 21.9 55.5 59.9 40.5 22.2 30.0 39.5 25.3 28.5 13.1 31.7 29.9 16.3 16.3 31.4 47.7 36.4 39.8 C2orf92 LINC01125 ENSG00000228486 "Chromosome 2 open reading frame 92" A0A1B0GVN3 2 97664217-97703064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 11.7" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Alveolar cells type 2: 7.5;Breast glandular cells: 3.3;Breast myoepithelial cells: 2.7;Club cells: 2.5;Endometrial ciliated cells: 3.7;Endometrial stromal cells: 2.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.6;HDLM-2: 2.0" "Not detected" "Not detected" NA NA "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.53e-2)" "unprognostic (8.76e-2)" "unprognostic (1.65e-2)" "unprognostic (2.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.09e-3)" "unprognostic (9.29e-2)" "unprognostic (1.22e-2)" "unprognostic (1.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.98e-3)" "unprognostic (2.76e-2)" "unprognostic (7.45e-7)" "unprognostic (5.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (5.23e-5)" 1.4 1.3 2.5 0.3 2.6 0.3 1.8 2.7 4.4 1.8 2.6 1.1 0.4 0.9 1.7 0.8 1.2 0.2 1.6 2.5 2.5 1.5 2.6 1.6 0.2 2.6 2.6 0.9 2.0 0.3 1.5 0.3 2.7 2.0 0.4 0.7 1.9 0.6 1.5 2.0 1.3 0.2 2.6 3.0 1.1 11.7 2.6 0.4 3.5 0.0 0.5 0.8 1.3 2.8 0.1 0.0 1.6 0.3 0.7 0.6 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.7 2.0 0.0 0.8 0.2 0.0 0.0 0.5 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.4 0.1 0.0 1.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.8 0.4 0.6 0.1 0.5 0.7 0.2 1.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.7 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.6 2.7 4.4 2.5 2.5 2.6 2.6 2.7 2.6 2.6 2.8 2.5 0.0 7.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 3.3 2.7 0.0 0.0 2.5 0.0 0.0 0.7 1.6 0.0 0.0 0.6 0.0 3.7 2.7 0.5 0.0 0.0 0.0 1.6 0.6 0.6 0.0 2.3 1.3 1.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.9 1.6 0.0 0.0 ZAP70 "SRK, STD, ZAP-70" ENSG00000115085 "Zeta chain of T cell receptor associated protein kinase 70" P43403 2 97713576-97739862 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 79.9" "Group enriched" "Detected in many" 4 "dendritic cells: 101.0;NK-cells: 155.5;T-cells: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 41 "gdT-cell: 137.4;MAIT T-cell: 93.2;memory CD4 T-cell: 71.7;memory CD8 T-cell: 108.3;naive CD4 T-cell: 50.8;naive CD8 T-cell: 79.8;NK-cell: 112.2;T-reg: 80.1" "Group enriched" "Detected in many" 56 "NK-cells: 112.2;T-cells: 137.4" "Group enriched" "Detected in some" 11 "JURKAT: 121.0;MOLT-4: 183.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002625, HPA003134" Enhanced NA NA 14000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB002625: , HPA003134: AB_1080629" "unprognostic (4.11e-3)" "prognostic favorable (6.89e-5)" "unprognostic (3.82e-3)" "prognostic favorable (9.66e-8)" "unprognostic (5.78e-2)" "prognostic favorable (3.93e-6)" "unprognostic (2.30e-3)" "unprognostic (1.09e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-2)" "unprognostic (9.23e-3)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.02e-8)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (6.40e-2)" "unprognostic (5.83e-3)" 3.3 1.3 0.5 28.0 0.6 24.8 1.9 0.5 0.9 1.7 0.7 4.0 5.8 1.4 0.5 2.3 2.2 5.4 1.4 0.5 0.7 2.8 3.9 8.7 57.0 0.8 1.3 0.8 1.0 0.4 1.1 0.9 0.7 2.5 1.5 0.0 2.3 0.8 2.0 2.4 18.5 0.5 0.6 35.5 6.7 2.7 1.2 79.9 3.5 2.8 17.7 4.9 2.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 121.0 0.0 0.7 0.0 0.0 183.4 0.5 0.1 0.0 0.0 7.2 0.1 9.1 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 14.1 0.1 0.0 0.0 0.3 0.3 0.5 137.4 0.4 93.2 0.2 71.7 108.3 0.3 1.6 50.8 79.8 2.2 112.2 1.0 0.9 80.1 64.2 0.5 0.6 0.5 0.9 0.5 0.7 0.8 1.3 0.7 0.6 1.2 0.6 0.8 9.6 13.6 0.3 3.9 1.5 0.0 0.0 0.0 0.0 0.8 0.5 3.0 0.0 0.0 0.0 0.0 0.1 101.0 0.2 1.9 0.2 1.0 1.6 0.5 0.8 0.0 8.8 0.2 0.0 0.0 1.8 4.6 0.4 2.5 0.1 2.5 0.7 2.2 0.0 0.2 0.0 0.0 2.8 2.2 0.7 0.0 3.4 1.8 2.8 5.0 0.0 155.5 0.0 0.1 0.0 0.0 0.0 28.0 0.1 0.0 0.5 0.0 0.0 0.0 14.3 0.6 1.3 2.1 0.2 1.4 0.0 105.6 0.1 0.1 0.2 TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Vesicles, Intermediate filaments" "HPA017678: AB_1858086, HPA017682: AB_1858087" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (7.42e-2)" "unprognostic (8.58e-2)" "unprognostic (4.18e-2)" "unprognostic (7.59e-3)" "unprognostic (3.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.10e-3)" "unprognostic (5.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.77e-1)" 12.1 12.2 7.2 20.7 7.5 17.5 10.6 7.2 7.6 18.8 9.3 25.8 18.5 16.3 8.5 14.3 15.3 15.8 13.0 7.4 5.5 12.1 13.5 12.4 25.4 6.1 7.5 16.3 19.0 27.5 11.1 18.3 6.1 16.6 23.2 11.4 13.4 11.5 24.4 24.1 19.4 16.5 6.6 18.4 26.2 14.7 10.3 18.4 12.8 22.3 23.1 14.1 10.4 8.6 26.1 15.7 28.8 21.0 29.6 35.8 31.4 37.8 36.5 18.9 22.7 20.3 36.8 41.3 20.4 39.3 32.2 18.4 30.5 50.5 28.0 29.4 19.8 30.0 10.6 29.3 33.4 28.2 38.6 34.4 20.2 33.7 34.7 32.0 23.5 19.8 18.1 42.8 58.2 15.7 20.6 17.9 15.8 20.2 33.4 29.7 18.3 18.3 19.3 30.7 32.3 15.7 24.4 16.7 23.2 30.7 14.0 25.8 28.1 49.1 22.4 23.9 14.7 18.1 26.8 20.6 38.5 24.3 33.9 3.7 1.3 3.6 1.7 1.6 1.9 2.1 1.5 1.7 1.7 1.9 1.7 2.3 0.9 2.5 1.6 2.4 1.0 1.0 7.2 7.5 7.2 7.6 7.4 5.5 6.1 7.5 6.1 6.6 10.3 8.6 29.4 16.0 27.9 90.1 41.2 19.8 17.7 16.3 24.5 28.3 17.3 16.0 34.7 15.7 23.4 20.2 22.9 15.4 33.1 62.2 3.9 9.7 14.4 88.9 33.9 19.3 30.1 23.5 113.1 24.0 12.7 23.5 60.1 86.8 23.5 21.3 22.9 26.0 24.5 25.2 99.7 45.6 10.2 29.2 18.5 20.1 20.8 35.8 12.4 87.1 47.0 14.1 9.2 92.5 129.8 18.1 40.1 19.2 36.3 17.9 27.4 7.0 38.2 19.3 13.1 31.9 24.9 21.2 26.0 25.0 25.6 13.5 22.4 28.0 36.6 16.0 VWA3B "DKFZp686F2227, MGC26733" ENSG00000168658 "Von Willebrand factor A domain containing 3B" Q502W6 2 98087116-98313299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.3;testis: 30.0" "Group enriched" "Detected in many" 5 "Early spermatids: 467.1;Late spermatids: 995.9" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.1" "Low region specificity" "Detected in all" "HPA036700, HPA036701" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA036700: AB_2675261, HPA036701: AB_10673505" "unprognostic (2.36e-2)" "unprognostic (4.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.01e-3)" "unprognostic (5.16e-2)" "unprognostic (3.27e-1)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (1.44e-2)" "unprognostic (4.53e-2)" "unprognostic (6.41e-2)" "unprognostic (2.63e-7)" "unprognostic (2.57e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (4.96e-2)" 0.0 0.0 1.4 0.0 1.1 0.0 0.0 0.9 0.7 0.6 5.0 0.1 0.0 0.2 0.0 0.0 22.3 0.0 0.0 1.3 1.5 0.1 0.0 2.5 0.0 7.0 5.8 0.2 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.1 30.0 1.2 0.7 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 0.9 0.7 1.3 1.5 7.0 5.8 3.7 4.8 1.2 2.7 0.3 0.0 1.1 11.8 0.1 0.3 1.7 2.2 0.0 1.0 0.1 0.3 0.9 0.0 12.1 1.8 31.3 0.0 0.0 0.8 0.0 0.0 467.1 53.8 0.6 0.6 1.8 0.0 1.9 0.4 0.2 0.8 4.6 1.6 0.0 0.1 1.1 0.0 0.2 0.0 1.0 2.8 6.1 0.0 0.8 995.9 4.7 0.7 0.0 3.7 0.6 0.7 0.0 1.5 0.7 0.2 2.7 5.7 0.2 0.4 0.2 0.0 124.5 0.5 0.0 0.5 1.0 17.6 6.0 0.0 0.4 0.0 0.1 0.2 1.0 0.8 CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.7;intestine: 4.2;pituitary gland: 10.1;retina: 5.9" "Cell type enriched" "Detected in some" 14 "Cone photoreceptor cells: 43.8" "Cancer enriched" "Detected in some" 9 "glioma: 7.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "U-87 MG: 6.8" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" "CAB079025: , HPA049378: AB_2732551" "unprognostic (2.34e-2)" "unprognostic (1.83e-2)" "unprognostic (4.96e-2)" "unprognostic (4.81e-2)" "unprognostic (1.13e-1)" "unprognostic (2.18e-1)" "unprognostic (4.17e-4)" "unprognostic (4.65e-2)" "unprognostic (1.86e-3)" "unprognostic (2.88e-1)" "unprognostic (3.85e-3)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (3.71e-2)" 0.1 0.0 0.6 0.5 0.5 0.0 0.2 0.2 0.8 0.0 2.9 4.2 1.0 0.0 0.0 1.5 0.4 0.0 0.0 0.7 5.6 0.1 0.0 0.1 0.0 3.4 1.5 0.0 0.3 0.0 10.1 0.0 3.6 0.0 1.1 5.9 0.2 0.2 0.0 0.0 1.3 0.8 5.7 0.0 0.9 0.5 1.3 0.0 0.0 0.0 0.0 0.6 0.1 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.2 0.8 0.7 5.6 3.4 1.5 3.6 5.7 1.3 4.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.7 0.0 0.0 0.0 43.8 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 0.1 0.0 0.0 3.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 1.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 INPP4A INPP4 ENSG00000040933 "Inositol polyphosphate-4-phosphatase type I A" Q96PE3 2 98444854-98594392 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.5;Inhibitory neurons: 124.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 67.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001628 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Nuclear membrane" "HPA001628: AB_10961254" "unprognostic (3.45e-1)" "unprognostic (2.39e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (3.70e-6)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "unprognostic (1.15e-3)" "unprognostic (9.44e-2)" "unprognostic (1.37e-2)" "unprognostic (1.23e-1)" "unprognostic (9.65e-2)" "unprognostic (3.70e-2)" "unprognostic (2.90e-2)" "unprognostic (4.89e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" 8.7 8.2 15.9 13.2 19.5 12.7 6.1 18.8 22.0 7.0 1.0 11.3 7.3 7.5 5.2 7.7 6.6 9.9 10.5 15.9 9.9 5.2 4.1 9.6 17.2 9.2 3.5 7.0 6.6 8.9 7.7 8.1 9.2 6.0 7.9 10.7 5.6 6.3 8.4 4.1 8.8 9.8 4.7 16.7 7.3 5.9 5.9 20.3 5.9 11.6 12.5 10.8 5.5 10.1 12.7 11.0 18.2 14.8 10.4 11.1 19.2 10.0 9.4 10.9 11.3 14.6 11.5 7.8 13.3 15.4 14.0 12.6 12.6 11.1 8.5 27.7 10.9 9.5 9.7 6.5 8.8 17.3 34.3 9.9 9.9 10.6 9.0 9.5 15.1 44.9 8.5 67.4 8.3 16.2 26.3 16.8 17.6 7.4 11.3 12.0 12.5 51.9 5.6 41.6 12.8 15.7 12.1 10.1 9.5 18.7 4.8 13.8 14.3 12.7 17.9 10.1 7.5 50.2 31.1 5.8 10.5 16.2 11.5 1.1 1.0 2.3 2.8 2.2 3.3 0.4 1.6 1.8 1.1 0.1 2.2 2.5 1.1 3.2 3.4 3.3 0.9 1.0 15.9 19.5 18.8 22.0 15.9 9.9 9.2 3.5 9.2 4.7 5.9 10.1 14.6 6.4 13.1 50.9 11.2 8.0 6.4 2.8 9.1 49.7 5.3 4.2 12.6 2.8 7.8 5.5 8.4 10.2 64.6 4.1 3.9 4.0 13.5 6.2 9.1 14.2 5.4 7.2 150.5 1.5 8.7 9.9 6.6 6.3 0.0 22.4 14.3 3.4 10.5 33.7 124.4 5.6 4.1 36.4 18.4 10.9 9.3 25.3 10.6 73.1 26.8 8.4 71.1 55.8 26.1 3.8 2.5 12.0 48.6 5.9 1.2 3.3 5.1 14.1 6.6 9.9 12.4 8.6 14.0 5.2 6.1 9.4 48.3 9.4 3.6 6.8 COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 180.0;Proximal tubular cells: 175.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057768 Uncertain Supported Mitochondria No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA057768: AB_2683521" "unprognostic (1.00e-1)" "unprognostic (4.19e-2)" "unprognostic (3.85e-2)" "unprognostic (1.67e-3)" "unprognostic (2.61e-2)" "unprognostic (7.11e-2)" "unprognostic (4.69e-2)" "prognostic favorable (2.65e-4)" "unprognostic (1.32e-3)" "unprognostic (3.71e-3)" "unprognostic (8.00e-3)" "unprognostic (3.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.29e-1)" "unprognostic (4.93e-2)" "unprognostic (2.50e-1)" "prognostic favorable (1.00e-5)" 14.9 20.9 39.7 10.4 40.9 9.7 18.5 46.0 46.0 19.0 35.6 21.4 14.7 18.5 29.8 11.7 19.2 11.0 21.2 40.1 40.4 26.6 22.8 12.9 16.3 40.7 40.8 21.2 15.6 22.0 23.5 13.4 40.6 19.8 14.4 38.4 15.1 17.6 28.5 16.8 17.7 12.4 40.3 19.4 17.8 12.9 42.6 17.3 22.5 22.0 15.5 18.1 14.1 44.1 18.5 7.9 24.4 17.5 28.1 22.6 20.4 10.6 8.5 11.4 11.8 16.3 15.1 9.6 18.4 8.7 21.7 13.1 21.2 11.5 13.8 24.5 18.5 13.3 15.2 26.0 20.4 13.1 11.6 22.7 23.6 8.1 10.5 19.7 12.0 26.6 18.6 10.8 12.4 14.6 17.2 22.9 16.9 19.8 16.7 10.4 17.2 21.1 24.8 9.9 18.4 23.1 9.1 11.3 27.6 27.4 13.9 26.4 11.1 17.2 15.3 10.4 9.0 17.6 25.0 12.0 21.0 28.0 14.5 20.2 24.9 29.4 23.9 23.5 20.3 23.6 21.0 22.5 24.0 25.3 25.5 25.5 28.0 20.1 25.8 31.2 31.1 22.9 39.7 40.9 46.0 46.0 40.1 40.4 40.7 40.8 40.6 40.3 42.6 44.1 39.5 16.0 28.7 10.4 27.3 10.5 26.3 46.5 28.5 25.5 45.5 62.6 66.6 37.1 32.6 47.8 6.2 36.9 34.8 26.3 180.0 43.4 28.0 52.8 30.4 30.6 27.0 29.4 12.0 24.5 38.8 29.8 21.9 35.6 26.6 33.3 31.8 63.6 52.8 21.9 12.4 37.2 59.0 38.1 12.5 14.9 32.6 30.5 28.4 4.7 41.3 51.4 54.6 8.5 19.1 30.8 29.6 35.0 24.0 34.4 46.1 175.0 49.2 32.0 13.1 23.5 29.7 118.4 33.8 32.5 11.6 32.7 23.5 46.1 33.2 33.6 UNC50 "GMH1, UNCL, URP" ENSG00000115446 "Unc-50 inner nuclear membrane RNA binding protein" Q53HI1 2 98608579-98618515 "Predicted membrane proteins" "Protein transport, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027009 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA027009: AB_1858620" "prognostic unfavorable (4.79e-4)" "unprognostic (3.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.74e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" "unprognostic (5.31e-2)" "unprognostic (6.31e-2)" "unprognostic (1.58e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "unprognostic (7.12e-3)" "unprognostic (4.82e-3)" 36.6 49.1 46.3 34.2 48.2 36.8 45.8 48.8 57.3 38.1 53.6 35.0 37.9 46.3 69.2 30.9 42.7 36.2 38.7 46.2 48.3 52.5 46.9 38.6 41.4 48.5 46.6 44.2 42.0 82.4 41.4 52.2 49.1 41.3 43.2 60.0 56.0 45.4 31.6 39.9 34.4 38.7 49.0 39.3 45.5 48.9 47.2 36.6 64.1 35.9 42.6 37.8 30.5 54.3 55.2 35.6 65.2 44.3 95.7 82.6 73.0 51.2 71.8 61.9 54.2 54.5 64.0 16.6 75.2 44.1 94.0 52.0 45.9 41.5 50.9 56.4 46.2 37.5 47.3 89.4 103.0 71.7 56.7 54.6 92.5 33.1 60.4 71.5 55.1 43.3 61.2 50.2 63.5 39.2 31.7 80.3 49.6 46.1 41.7 20.1 47.3 58.8 68.9 48.6 24.2 35.6 35.9 47.3 86.5 75.8 40.7 91.9 42.7 67.4 41.3 34.5 35.0 76.1 63.2 44.2 63.6 51.7 60.1 61.6 54.3 66.7 50.6 54.9 43.9 52.8 42.2 47.9 54.9 48.1 46.2 52.9 45.3 58.5 51.4 51.3 37.4 44.2 46.3 48.2 48.8 57.3 46.2 48.3 48.5 46.6 49.1 49.0 47.2 54.3 45.3 25.6 31.0 13.7 35.7 47.2 51.2 139.4 42.7 36.7 46.7 40.8 39.5 38.6 85.8 35.0 16.7 118.6 41.2 27.4 33.2 52.3 47.7 38.3 35.3 48.3 21.6 19.1 21.2 53.2 77.1 58.9 19.4 30.7 27.3 23.7 47.2 33.9 73.2 33.7 24.1 34.1 85.5 31.3 33.3 29.9 54.7 33.0 44.4 19.7 41.7 84.6 48.4 19.1 25.8 40.7 33.0 74.9 51.0 75.7 29.0 46.6 73.8 49.8 46.0 45.0 58.9 215.1 58.7 34.6 49.7 152.6 29.2 39.1 30.1 44.6 MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.0" "Cell type enhanced" "Detected in many" "Microglial cells: 175.2;Proximal enterocytes: 132.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 127.2;HUVEC TERT2: 48.3;JURKAT: 86.5;TIME: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "HPA007608: AB_10602008" "prognostic unfavorable (4.30e-4)" "unprognostic (1.15e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.48e-8)" "unprognostic (1.35e-1)" "unprognostic (2.28e-2)" "unprognostic (3.82e-3)" "unprognostic (1.89e-1)" "unprognostic (3.76e-1)" "unprognostic (3.58e-1)" "unprognostic (2.80e-2)" "unprognostic (2.32e-2)" "unprognostic (4.17e-2)" "unprognostic (1.50e-1)" "unprognostic (4.62e-2)" "unprognostic (4.04e-2)" "unprognostic (2.04e-1)" 11.2 7.8 13.2 20.8 17.8 96.0 12.5 26.1 15.6 8.9 15.1 24.4 29.5 5.8 3.7 6.3 7.0 12.7 7.6 13.1 15.2 27.5 9.7 16.9 21.1 16.4 15.8 3.2 38.8 28.0 9.8 19.6 15.5 7.5 25.5 5.4 25.9 6.4 3.8 4.1 43.8 11.5 18.1 8.1 11.3 6.3 15.5 20.5 8.7 4.7 18.2 13.1 4.7 22.9 8.8 1.7 3.4 7.3 0.0 0.0 127.2 0.0 0.1 0.9 0.0 21.0 10.6 0.0 18.9 0.0 2.4 0.4 7.2 1.0 0.2 10.6 7.9 0.5 0.0 36.7 0.2 17.8 6.4 0.0 4.7 0.0 0.7 0.3 48.3 86.5 1.6 9.2 0.0 17.3 39.3 30.9 1.1 7.6 1.4 9.8 0.0 10.5 24.8 17.6 10.4 3.3 2.5 32.2 4.8 9.2 7.6 23.8 78.8 0.0 4.0 0.1 2.6 3.2 7.6 2.2 0.0 26.7 0.6 7.0 5.1 12.7 20.8 1.0 27.5 3.6 25.2 23.7 3.8 2.5 32.6 27.2 14.0 15.3 2.5 17.1 16.0 12.5 13.2 17.8 26.1 15.6 13.1 15.2 16.4 15.8 15.5 18.1 15.5 22.9 80.8 54.5 25.7 19.2 22.7 9.9 21.1 6.1 11.4 19.8 28.2 15.6 13.4 11.5 17.6 22.0 4.2 6.2 116.9 92.4 21.5 20.8 12.7 14.2 3.8 39.8 53.0 6.3 58.0 29.8 77.9 7.2 19.4 35.1 13.3 5.1 18.9 10.4 57.2 48.8 48.6 41.3 34.6 33.9 18.3 17.5 2.5 54.5 10.6 175.2 21.0 13.4 89.6 36.7 42.0 21.6 58.2 2.2 31.4 17.8 132.4 27.3 7.1 4.8 6.6 6.8 4.9 2.5 7.7 8.6 10.5 14.9 112.2 0.7 40.9 30.2 CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.8;epididymis: 31.6" "Cell type enriched" "Detected in some" 9 "Adipocytes: 35.9" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 6 "amygdala: 12.8;basal ganglia: 20.0;cerebral cortex: 30.8;hippocampal formation: 29.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 41.0;HDLM-2: 61.7;Karpas-707: 17.4;MCF7: 16.3;SiHa: 17.3;SK-BR-3: 22.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 19.1;basal ganglia: 45.5;cerebral cortex: 36.9;hippocampal formation: 54.9;olfactory bulb: 15.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 68: Epididymis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: AB_2681337, HPA061678: AB_2684584" "unprognostic (3.56e-3)" "unprognostic (1.23e-3)" "unprognostic (5.88e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.24e-1)" "unprognostic (3.67e-3)" "unprognostic (2.12e-1)" "unprognostic (5.10e-2)" "unprognostic (7.65e-2)" "unprognostic (3.23e-2)" "unprognostic (3.61e-2)" "prognostic favorable (1.13e-5)" "unprognostic (1.22e-1)" "unprognostic (3.34e-1)" "prognostic favorable (1.33e-5)" "unprognostic (2.22e-2)" 5.0 0.9 12.8 1.5 20.0 0.5 5.1 0.0 30.8 5.1 0.0 5.9 8.0 2.1 31.6 11.2 22.6 2.9 3.4 29.7 0.0 4.1 0.3 6.0 0.8 0.0 0.0 0.6 4.7 7.7 6.6 4.5 0.0 2.3 4.6 0.1 11.0 4.6 1.7 6.4 7.5 2.3 0.0 1.3 8.3 6.2 0.0 1.0 5.0 1.5 1.8 2.2 5.5 3.6 8.4 0.4 0.2 3.2 0.0 0.0 41.0 0.0 0.0 0.0 0.0 0.4 4.9 0.0 10.4 0.0 0.2 7.4 0.3 0.4 0.0 61.7 1.2 0.0 0.5 0.5 0.0 0.0 0.1 0.3 2.3 0.1 1.2 0.1 2.5 0.0 0.0 17.4 0.0 16.3 0.2 1.3 0.1 8.3 0.9 0.0 0.0 0.8 3.2 6.5 5.8 0.9 17.3 22.5 0.1 0.0 8.7 1.4 10.7 0.0 1.3 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.8 20.0 0.0 30.8 29.7 0.0 0.0 0.0 0.0 0.0 0.0 3.6 35.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 TSGA10 "CEP4L, CT79" ENSG00000135951 "Testis specific 10" Q9BZW7 2 98997261-99154964 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 51.5" "Cell type enhanced" "Detected in all" "Early spermatids: 458.9;Late spermatids: 294.2;Oligodendrocytes: 144.9;Spermatocytes: 206.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036879 Approved Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA036879: AB_10671715" "unprognostic (1.71e-3)" "unprognostic (6.68e-2)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.98e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-5)" "unprognostic (2.32e-1)" "unprognostic (2.82e-6)" "unprognostic (1.06e-2)" "unprognostic (9.91e-3)" "unprognostic (9.79e-2)" "unprognostic (8.37e-4)" 1.1 1.0 1.8 0.6 1.6 0.7 1.4 1.6 1.9 1.3 3.7 0.9 1.0 1.1 1.6 0.6 12.6 1.1 0.2 1.8 1.6 3.0 0.5 1.6 1.0 3.4 3.5 0.5 1.7 1.6 2.5 0.4 2.5 1.0 1.3 2.6 1.1 0.6 0.1 1.9 0.6 0.3 2.7 0.8 1.4 51.5 1.5 1.1 3.1 0.2 0.8 0.6 0.4 3.7 0.8 0.2 1.2 0.5 0.6 0.7 0.9 0.0 0.1 0.3 0.2 0.2 0.8 0.7 0.2 0.0 0.5 0.2 0.2 0.2 0.3 1.0 0.8 0.1 0.0 0.3 0.0 0.5 1.7 0.9 1.0 0.1 0.1 0.7 0.0 0.9 0.0 0.0 0.6 0.2 0.2 0.4 0.1 0.3 0.2 0.3 0.1 0.2 4.2 0.7 1.7 0.2 0.9 0.7 0.2 1.3 0.2 0.3 0.4 0.2 0.4 0.0 0.1 0.6 0.3 0.3 0.3 1.0 0.4 0.1 0.2 0.2 0.6 0.0 0.7 0.7 0.7 0.8 0.0 0.8 1.1 0.7 0.0 1.0 0.0 0.4 0.7 0.3 1.8 1.6 1.6 1.9 1.8 1.6 3.4 3.5 2.5 2.7 1.5 3.7 3.1 3.2 9.2 35.3 13.3 3.6 10.3 8.6 6.2 19.3 13.9 15.4 7.1 17.2 14.5 23.9 29.2 9.7 5.6 4.7 25.4 8.4 458.9 80.6 4.5 4.0 15.5 8.6 73.4 10.5 4.3 5.8 8.6 10.9 5.1 5.3 4.2 7.1 4.6 20.2 57.9 6.7 12.2 3.1 1.4 294.2 11.1 5.1 1.8 23.4 4.5 21.1 15.5 27.6 144.9 4.7 12.2 9.8 8.1 7.8 8.0 12.9 107.9 36.6 6.6 5.7 6.2 206.8 36.6 5.6 4.4 9.3 8.9 5.9 8.4 7.9 C2orf15 MGC29762 ENSG00000273045 "Chromosome 2 open reading frame 15" Q8WU43 2 99141707-99151669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 15.6;Proximal tubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 12.6;SCLC-21H: 12.2" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.61e-2)" "unprognostic (7.88e-2)" "unprognostic (4.22e-2)" "unprognostic (4.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.99e-2)" "unprognostic (5.37e-2)" "unprognostic (9.05e-3)" "unprognostic (1.62e-2)" "prognostic favorable (4.95e-4)" "unprognostic (2.54e-3)" "unprognostic (1.04e-1)" "prognostic favorable (1.23e-4)" "unprognostic (2.06e-1)" "unprognostic (4.22e-4)" "unprognostic (5.08e-1)" "unprognostic (2.97e-2)" 0.4 0.7 1.5 0.8 1.5 1.3 3.5 3.3 1.8 2.4 1.7 2.1 4.1 1.2 6.0 1.4 3.9 1.8 0.3 1.4 1.6 5.4 0.5 1.4 1.5 1.5 1.5 0.8 3.1 6.1 0.7 1.1 1.7 1.3 2.4 3.8 2.7 1.8 0.3 2.0 3.2 0.3 1.2 1.0 3.8 1.4 2.1 1.2 6.3 0.0 1.6 1.7 0.1 2.5 9.8 1.5 0.3 1.3 0.2 0.0 7.2 0.0 0.7 0.5 0.3 10.1 7.0 4.3 3.0 0.0 0.8 6.0 1.4 1.1 0.0 0.8 4.5 0.3 1.8 6.8 0.1 1.5 1.8 0.2 2.2 0.0 0.7 0.4 0.0 5.5 0.4 0.9 0.4 8.5 1.2 1.9 2.2 5.3 2.1 0.7 0.2 4.8 9.9 12.6 12.2 1.5 1.0 10.2 0.4 1.7 8.2 0.4 0.0 0.5 0.5 0.3 0.4 2.9 4.8 1.5 0.2 1.4 0.1 0.3 0.3 0.2 2.0 0.2 4.7 1.8 3.2 2.5 0.1 2.0 4.3 2.2 0.9 3.8 0.1 0.4 1.7 1.2 1.5 1.5 3.3 1.8 1.4 1.6 1.5 1.5 1.7 1.2 2.1 2.5 0.4 3.2 3.1 0.7 2.5 1.1 1.7 2.1 0.0 5.6 5.4 4.6 0.4 2.8 2.2 7.3 6.2 6.8 0.7 0.8 15.6 5.5 1.8 3.7 0.4 0.9 1.2 0.8 3.3 2.9 0.7 0.6 1.1 2.5 0.0 1.3 0.4 0.1 0.6 6.7 2.5 2.9 0.0 0.0 1.4 0.3 0.6 0.5 0.0 0.0 0.5 4.1 0.0 0.5 2.8 2.8 3.7 0.4 0.7 1.5 3.7 9.8 7.9 7.7 0.0 0.9 0.5 3.4 3.7 0.9 1.4 2.1 1.8 1.6 3.4 1.3 LIPT1 "MGC12290, MGC13378" ENSG00000144182 "Lipoyltransferase 1" Q9Y234 2 99154955-99163157 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 41.0;Spermatocytes: 40.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034802 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034802: AB_10669851" "unprognostic (1.13e-2)" "unprognostic (7.21e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-2)" "unprognostic (7.46e-2)" "unprognostic (6.48e-2)" "unprognostic (1.13e-3)" "prognostic favorable (5.70e-4)" "unprognostic (1.49e-2)" "unprognostic (4.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.32e-3)" "unprognostic (1.72e-1)" "unprognostic (4.92e-2)" "unprognostic (3.16e-1)" "prognostic favorable (9.60e-8)" 7.1 7.8 6.7 6.8 7.5 12.3 10.9 7.4 8.3 8.1 6.3 6.7 8.4 8.1 14.1 5.1 8.1 6.5 8.5 6.9 7.8 11.2 8.1 5.7 10.7 7.2 7.1 11.8 7.3 6.3 6.7 4.9 7.2 9.2 7.3 7.5 8.9 6.0 9.1 7.0 8.4 5.6 7.2 11.9 6.9 13.5 7.2 5.3 11.3 8.9 7.4 6.3 5.6 10.4 6.2 4.0 5.4 9.2 9.3 11.0 13.0 4.0 4.7 3.1 3.4 9.8 10.3 9.9 8.4 2.4 8.4 5.4 6.6 5.0 6.1 10.6 12.0 10.3 5.1 8.7 9.9 7.0 5.1 6.5 8.0 5.6 12.7 6.3 8.8 11.4 10.0 5.8 5.4 5.0 6.9 13.4 13.8 6.0 9.9 11.7 5.8 10.4 10.1 9.2 5.2 5.0 5.6 6.2 14.8 9.8 6.6 14.2 6.4 4.6 6.4 4.1 3.8 9.1 12.9 10.7 4.8 11.4 6.7 15.4 10.3 16.1 16.8 9.6 20.9 14.2 18.9 18.5 5.6 12.4 23.6 19.9 2.7 18.4 9.5 5.6 12.3 11.6 6.7 7.5 7.4 8.3 6.9 7.8 7.2 7.1 7.2 7.2 7.2 10.4 9.3 3.2 6.7 6.5 7.5 3.6 10.8 14.5 6.2 5.2 3.9 7.9 6.6 2.8 8.5 12.9 2.1 7.6 9.7 3.3 13.7 5.1 41.0 3.6 6.5 7.8 6.1 3.2 5.3 3.4 4.3 7.2 3.1 3.4 5.1 8.3 12.8 2.2 7.2 11.8 5.5 6.1 6.1 7.9 2.2 25.4 9.6 4.6 1.8 1.9 8.5 12.1 18.6 9.5 14.3 3.4 6.9 7.5 2.7 5.6 15.9 11.8 9.0 10.6 6.6 13.1 5.8 40.6 12.8 3.0 4.3 5.3 8.9 5.0 6.2 6.2 AC092587.1 ENSG00000273155 "Novel LIPT1-MRPL30 readthrough" 2 99154998-99195298 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Cytotrophoblasts: 1.6;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 2.0;Hofbauer cells: 1.5;Proximal tubular cells: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in some" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (5.56e-3)" "unprognostic (2.80e-1)" "unprognostic (5.47e-2)" "unprognostic (2.46e-1)" "unprognostic (1.32e-1)" "unprognostic (5.70e-2)" "unprognostic (8.45e-3)" "unprognostic (3.84e-2)" "unprognostic (2.41e-2)" "unprognostic (3.36e-1)" "unprognostic (2.82e-1)" "unprognostic (2.19e-1)" "unprognostic (5.36e-2)" "unprognostic (3.81e-2)" "unprognostic (9.17e-2)" "unprognostic (2.80e-1)" "unprognostic (3.25e-1)" 0.6 0.6 0.0 1.1 0.1 0.6 0.5 0.4 0.6 0.6 0.0 0.5 0.1 0.6 0.1 0.5 0.3 0.5 1.3 0.1 0.1 0.5 0.5 0.4 0.3 0.0 0.1 0.5 0.3 0.3 0.3 0.3 0.0 0.4 0.4 0.2 0.4 0.3 1.2 0.3 0.7 0.3 0.0 0.3 0.4 0.3 0.0 0.0 0.4 0.4 0.5 0.5 0.5 0.2 0.7 1.0 0.7 1.3 0.2 2.1 0.3 0.0 0.4 0.4 0.6 1.0 0.6 0.4 1.1 0.2 0.3 0.9 0.5 0.6 1.1 0.6 0.0 0.0 0.5 1.7 0.0 1.7 0.0 0.3 0.8 0.9 0.2 0.1 0.4 0.4 1.4 0.1 0.2 0.3 1.0 1.4 0.9 0.2 1.3 0.8 0.3 0.8 0.6 0.6 0.2 0.8 0.3 0.7 0.4 1.2 0.9 1.3 0.9 0.6 0.9 0.0 0.3 0.1 0.3 0.5 0.5 1.0 0.2 0.4 1.3 0.8 1.0 0.9 0.7 0.8 1.0 0.9 1.3 0.8 1.0 1.2 0.5 1.0 1.2 0.9 1.3 0.5 0.0 0.1 0.4 0.6 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.8 0.0 1.6 0.1 0.0 3.9 0.9 0.0 0.1 0.3 0.4 0.0 0.0 0.0 2.2 2.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 MITD1 LOC129531 ENSG00000158411 "Microtubule interacting and trafficking domain containing 1" Q8WV92 2 99161427-99181058 "Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036162, HPA036163" Approved Enhanced Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036162: AB_10672236, HPA036163: AB_2674978" "prognostic favorable (5.96e-4)" "unprognostic (1.67e-2)" "unprognostic (3.09e-1)" "unprognostic (2.79e-1)" "unprognostic (2.02e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.39e-1)" "unprognostic (5.35e-2)" "unprognostic (1.01e-2)" "unprognostic (1.09e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.32e-11)" "unprognostic (2.38e-1)" "unprognostic (2.40e-1)" "unprognostic (6.91e-2)" "prognostic favorable (5.46e-8)" 17.9 16.8 12.3 25.1 12.9 13.2 17.1 12.3 15.5 17.2 11.8 17.5 15.4 16.8 14.3 17.9 15.8 12.7 13.6 11.9 12.9 18.7 17.3 14.2 36.5 13.0 12.7 17.0 11.7 9.1 11.0 16.6 12.9 13.5 20.0 22.1 13.5 11.9 10.7 15.8 19.1 17.0 12.4 22.3 17.4 7.0 12.7 27.0 15.1 11.2 29.1 16.8 16.2 13.7 58.0 15.3 30.5 11.8 35.1 45.2 41.9 27.1 37.8 37.2 50.3 18.8 47.6 40.0 30.4 22.2 84.9 43.0 30.0 29.9 61.7 57.2 20.6 35.4 22.3 40.4 52.2 60.2 20.1 35.9 25.4 32.6 31.2 34.3 42.4 37.8 29.6 24.1 34.0 13.8 57.8 88.5 25.8 37.1 30.0 32.4 43.8 34.7 47.2 32.1 10.0 14.7 26.5 24.3 35.0 52.8 12.9 47.1 32.1 23.0 30.2 24.3 34.1 28.2 23.6 55.5 41.7 50.2 23.4 19.2 24.7 18.2 17.5 22.8 19.7 30.6 24.8 20.8 22.0 28.4 23.6 19.3 28.0 26.0 21.8 29.8 23.1 12.8 12.3 12.9 12.3 15.5 11.9 12.9 13.0 12.7 12.9 12.4 12.7 13.7 31.0 25.6 19.9 22.9 51.2 18.9 30.3 78.2 22.2 13.4 19.5 22.9 12.3 31.5 41.6 35.0 14.6 48.2 39.1 28.1 45.0 46.9 18.8 28.2 34.8 33.1 15.7 27.3 18.3 61.2 34.9 27.6 19.9 24.7 30.4 20.2 30.0 31.2 51.0 11.8 16.9 25.5 40.7 24.5 22.3 6.2 51.0 31.0 23.2 11.2 50.5 26.2 40.2 15.6 38.4 57.3 33.5 39.5 23.3 20.2 32.9 63.4 34.5 55.4 39.5 22.4 24.4 14.4 15.5 20.0 17.5 22.6 42.4 26.4 27.5 19.6 MRPL30 "MRP-L28, RPML28" ENSG00000185414 "Mitochondrial ribosomal protein L30" Q8TCC3 2 99181152-99199561 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047255 Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "HPA047255: AB_2680002" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "unprognostic (9.77e-2)" "unprognostic (7.87e-2)" "unprognostic (1.65e-1)" "unprognostic (4.34e-2)" "unprognostic (2.60e-3)" "unprognostic (2.53e-1)" "unprognostic (9.37e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.25e-2)" "unprognostic (1.50e-3)" "unprognostic (2.84e-1)" "unprognostic (3.49e-2)" "unprognostic (3.16e-2)" "unprognostic (2.72e-1)" 9.9 12.5 4.0 5.0 4.1 3.4 9.3 4.8 4.5 10.0 2.8 9.8 7.1 9.8 4.1 14.6 8.0 4.0 16.7 4.3 4.1 12.4 13.6 6.0 5.2 3.2 3.3 9.6 11.3 7.4 7.2 5.1 3.4 8.6 6.8 6.0 9.9 5.6 29.6 10.6 8.1 5.3 3.2 7.1 10.1 4.0 4.1 7.4 7.0 21.1 7.0 9.3 10.1 4.3 30.7 8.5 14.4 10.6 9.6 15.7 14.3 12.7 11.1 15.3 12.3 23.3 7.4 22.8 7.7 11.3 9.2 15.1 25.9 30.8 24.9 14.8 21.3 23.4 10.9 25.3 13.0 19.8 8.2 13.6 10.6 12.3 23.1 11.8 26.3 12.3 36.3 14.2 14.8 10.8 29.0 16.6 15.6 10.2 24.5 28.1 28.4 19.9 17.7 17.5 20.2 20.3 9.8 21.4 29.3 14.5 17.1 16.4 13.0 20.7 11.2 10.8 15.6 17.2 22.7 33.7 14.2 17.3 22.1 3.1 4.7 3.2 3.5 4.9 3.6 4.6 2.7 5.1 4.0 4.2 3.6 3.4 1.5 3.8 3.1 3.8 4.3 3.3 4.0 4.1 4.8 4.5 4.3 4.1 3.2 3.3 3.4 3.2 4.1 4.3 15.9 9.6 7.5 11.8 16.2 0.6 12.7 1.0 20.5 9.4 14.0 15.7 27.3 15.7 6.7 11.0 6.2 22.5 15.1 15.4 35.2 23.3 3.0 16.9 28.1 11.5 13.8 16.6 18.9 24.7 25.3 13.6 13.7 20.2 6.3 15.1 14.3 25.8 19.9 16.8 17.3 19.5 2.0 19.7 0.5 2.4 22.4 14.9 1.8 11.2 24.2 9.8 21.6 9.0 17.2 29.7 11.9 22.6 19.1 9.0 20.6 34.6 5.3 9.3 0.0 10.8 12.3 7.5 13.8 22.9 0.9 13.4 14.4 17.9 19.8 10.3 LYG2 LYGH ENSG00000185674 "Lysozyme g2" Q86SG7 2 99242246-99255282 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.8;retina: 3.5;skin 1: 8.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.7;Cone photoreceptor cells: 14.6;Excitatory neurons: 19.6;Horizontal cells: 15.2;Inhibitory neurons: 17.5;Rod photoreceptor cells: 29.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 0.9" "Region enriched" "Detected in some" 4 "cerebellum: 4.8" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "THP-1: 1.7;U-937: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039179 Uncertain "Secreted in other tissues" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA039179: AB_10794633" "unprognostic (5.12e-2)" "unprognostic (8.70e-3)" "unprognostic (6.29e-2)" "unprognostic (3.91e-2)" "unprognostic (1.47e-1)" "unprognostic (7.29e-2)" "unprognostic (1.86e-2)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (1.30e-2)" "unprognostic (1.30e-5)" "unprognostic (1.40e-3)" "unprognostic (1.08e-13)" "unprognostic (9.98e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-2)" "unprognostic (9.24e-3)" 0.2 0.1 0.4 0.1 0.5 0.5 0.0 4.8 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 3.5 0.3 0.0 0.3 8.8 0.1 0.0 0.0 0.2 0.2 1.4 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.3 0.4 0.4 0.5 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.3 0.9 0.2 0.0 1.0 0.2 0.0 0.0 0.1 0.4 0.1 0.2 0.6 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 1.0 0.2 0.6 0.3 0.0 1.2 0.2 0.6 0.4 1.1 0.3 0.5 0.1 0.0 0.0 0.0 0.4 0.3 1.7 0.6 0.6 0.4 0.1 0.4 0.2 0.8 0.1 0.3 2.5 0.4 0.0 0.2 0.1 0.3 0.0 0.2 0.6 0.8 0.4 0.0 1.1 0.3 0.3 0.1 0.2 0.0 0.9 0.1 0.0 0.4 0.5 4.8 1.0 0.6 0.1 0.0 0.0 0.2 0.0 0.4 0.7 0.9 0.0 0.0 5.5 1.2 0.6 0.5 0.3 0.0 13.7 0.8 0.9 0.3 5.7 0.1 0.0 14.6 0.9 1.6 0.1 0.0 0.1 6.1 0.6 0.9 0.7 0.0 0.0 19.6 0.0 0.2 0.8 0.0 0.3 0.0 0.5 1.1 0.0 0.2 15.2 17.5 0.0 0.0 0.9 0.3 2.2 0.0 0.2 1.8 0.0 0.2 6.9 4.1 7.5 8.9 0.1 0.0 0.7 0.0 0.7 0.3 0.3 0.0 29.9 0.0 2.0 0.9 1.8 1.6 0.0 0.4 0.3 0.9 0.2 0.4 0.1 LYG1 SALW1939 ENSG00000144214 "Lysozyme g1" Q8N1E2 2 99284238-99304742 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.5" "Cell type enriched" "Detected in some" 7 "Proximal tubular cells: 161.4" "Cancer enriched" "Detected in many" 15 "renal cancer: 31.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.53e-2)" "unprognostic (3.13e-2)" "unprognostic (1.53e-2)" "unprognostic (3.73e-1)" "unprognostic (9.74e-2)" "unprognostic (3.76e-4)" "unprognostic (6.94e-4)" "unprognostic (2.58e-2)" "unprognostic (4.72e-2)" "unprognostic (9.74e-3)" "unprognostic (5.01e-2)" "unprognostic (1.06e-2)" "prognostic favorable (8.44e-4)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (1.07e-1)" "unprognostic (2.31e-3)" 1.9 1.6 3.1 1.2 3.3 0.9 2.1 6.0 4.3 3.6 1.8 2.3 1.2 2.3 1.8 1.3 2.3 0.8 2.0 3.0 2.6 23.5 5.8 1.9 1.6 3.2 2.8 2.4 1.6 0.2 2.0 0.7 3.2 3.3 1.1 2.6 1.7 0.7 2.1 1.7 2.8 0.9 2.6 4.7 1.7 5.5 3.1 2.4 2.6 0.4 1.3 2.5 2.3 4.1 0.3 2.3 1.7 2.8 3.9 2.2 1.9 0.9 1.0 0.9 1.5 0.4 2.0 0.5 1.5 0.4 0.2 1.0 2.3 0.3 1.1 1.6 1.4 1.3 2.0 0.7 0.7 0.4 3.1 1.8 2.4 1.4 0.6 2.0 0.5 3.0 0.7 1.5 1.0 0.5 1.2 4.0 0.4 1.2 2.1 2.9 1.0 0.8 3.9 0.9 1.0 0.6 0.3 0.7 0.6 2.0 0.3 0.4 1.3 1.2 1.4 2.0 1.0 1.7 1.0 0.3 0.3 2.4 0.5 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.1 3.1 3.3 6.0 4.3 3.0 2.6 3.2 2.8 3.2 2.6 3.1 4.1 0.6 0.0 0.0 3.6 1.5 0.0 0.2 0.6 0.0 1.0 0.8 0.8 0.5 1.5 1.5 1.8 2.1 0.3 0.5 0.5 21.5 0.7 10.8 0.2 0.3 0.5 0.0 0.0 4.6 0.2 0.2 0.4 0.0 0.2 4.5 0.8 1.1 0.5 0.3 0.0 4.2 0.3 0.0 0.3 0.3 4.8 0.3 1.4 0.0 2.8 0.8 0.2 0.0 2.0 5.6 0.6 0.1 0.4 0.0 0.6 0.2 161.4 0.2 0.6 0.0 0.1 0.5 2.4 1.1 0.0 0.0 0.5 0.6 0.3 0.4 0.2 TXNDC9 APACD ENSG00000115514 "Thioredoxin domain containing 9" O14530 2 99318982-99340702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031844, HPA031845, HPA031846" Approved Enhanced Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA031844: AB_10600838, HPA031845: AB_10670968, HPA031846: AB_10669916" "unprognostic (3.63e-3)" "unprognostic (4.26e-2)" "unprognostic (7.28e-2)" "unprognostic (3.12e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (4.31e-4)" "prognostic unfavorable (9.63e-7)" "unprognostic (2.06e-2)" "unprognostic (9.09e-2)" "unprognostic (1.42e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.32e-1)" "unprognostic (2.47e-3)" "unprognostic (2.03e-1)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" 18.7 17.9 10.0 21.3 10.8 17.5 28.7 11.0 13.2 19.3 10.4 24.6 18.4 16.6 25.9 26.1 18.1 18.6 28.6 10.8 11.7 28.8 27.2 20.1 29.2 11.6 11.5 10.7 10.9 15.4 11.3 23.5 11.9 19.6 26.3 11.0 15.1 16.1 18.2 19.0 17.6 24.4 11.8 18.6 18.5 17.8 10.9 26.1 24.8 16.2 34.0 24.9 14.1 12.5 78.3 27.6 55.0 27.7 55.8 57.8 65.8 83.1 79.5 88.5 85.0 71.1 55.5 58.0 66.9 72.6 77.0 52.7 55.2 88.2 102.6 44.0 53.5 60.4 34.5 77.0 54.2 71.8 44.2 53.0 76.7 74.3 53.8 46.1 101.9 32.1 73.0 51.1 103.7 41.5 43.4 63.6 43.4 46.4 68.7 32.5 53.0 56.4 123.9 62.6 37.1 31.5 41.7 56.2 93.7 69.8 64.3 60.9 69.4 65.1 62.7 40.6 62.6 21.2 37.1 65.6 51.9 76.8 58.6 110.6 54.1 61.1 56.7 60.5 70.2 69.1 66.6 64.4 60.3 57.6 61.9 62.5 53.5 77.7 82.6 60.9 91.2 87.0 10.0 10.8 11.0 13.2 10.8 11.7 11.6 11.5 11.9 11.8 10.9 12.5 46.6 9.6 13.4 8.8 33.4 35.2 29.7 137.1 25.0 11.3 21.5 26.3 27.6 25.8 67.0 36.8 8.4 75.7 31.3 26.2 84.1 79.8 75.7 37.3 29.9 46.2 20.9 47.8 13.3 69.4 82.5 29.2 22.4 25.5 17.7 21.0 38.2 24.4 56.9 13.5 12.8 25.7 91.6 25.4 31.3 21.1 27.7 30.2 26.6 4.7 55.5 26.9 44.3 12.5 16.7 84.5 21.6 23.3 31.8 24.0 21.9 121.5 72.8 19.8 26.3 17.8 89.3 52.8 42.7 29.4 38.9 81.3 35.1 40.1 26.6 21.9 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 REV1 REV1L ENSG00000135945 "REV1 DNA directed polymerase" Q9UBZ9 2 99400475-99490035 "Predicted intracellular proteins" "DNA damage, DNA repair, DNA synthesis" "DNA-binding, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044534, HPA051036" Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "HPA044534: AB_2678975, HPA051036: AB_2681319" "unprognostic (3.05e-1)" "unprognostic (3.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (7.87e-3)" "unprognostic (1.30e-3)" "unprognostic (3.56e-3)" "unprognostic (2.78e-3)" "unprognostic (1.01e-1)" "unprognostic (7.33e-2)" "prognostic unfavorable (2.03e-4)" "unprognostic (3.17e-1)" "unprognostic (1.45e-1)" "unprognostic (4.36e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-3)" 9.8 11.6 7.0 6.1 7.6 7.0 11.2 13.1 9.6 11.9 9.4 9.3 6.1 14.2 17.3 10.5 11.4 7.9 12.4 7.2 8.7 9.0 10.0 11.2 10.0 7.0 7.4 12.1 6.9 8.8 10.4 7.3 6.8 11.2 9.2 12.2 9.4 12.0 15.7 10.3 9.0 10.1 6.9 9.4 8.2 9.6 8.5 9.7 10.3 23.7 10.0 10.5 11.5 8.5 7.9 2.0 12.4 4.7 9.5 9.3 13.0 8.6 10.8 9.9 11.3 4.6 7.5 15.9 6.7 9.2 10.4 10.9 9.3 11.5 15.3 7.0 5.8 8.1 7.7 10.5 10.6 10.6 16.5 9.1 13.7 8.9 13.0 11.1 12.9 8.1 9.4 5.3 11.1 5.2 11.2 19.0 8.9 5.1 5.2 17.4 8.8 7.0 12.3 13.4 8.0 8.5 7.6 6.4 11.2 13.3 6.6 15.2 9.1 11.7 9.7 4.9 5.7 7.2 7.8 12.8 4.8 13.4 9.2 0.0 0.2 0.0 0.3 0.2 0.2 0.1 0.5 0.4 0.3 0.4 0.9 0.7 0.1 0.3 0.1 0.1 0.3 0.1 7.0 7.6 13.1 9.6 7.2 8.7 7.0 7.4 6.8 6.9 8.5 8.5 45.3 70.5 61.9 59.4 27.7 48.3 57.5 37.8 58.6 84.2 21.7 20.4 52.5 20.0 38.6 22.0 39.6 32.9 17.5 24.1 5.9 18.4 29.2 41.6 32.8 31.6 17.5 35.7 71.3 18.1 20.0 33.8 31.6 30.0 25.3 32.4 23.6 18.0 19.1 82.4 78.2 16.3 26.4 17.6 28.3 21.6 27.1 20.6 19.6 53.4 27.3 36.7 14.4 60.3 77.0 16.4 25.6 46.3 23.3 51.0 30.0 12.5 33.7 57.2 26.3 51.2 28.8 52.1 53.8 36.3 35.5 35.2 26.8 39.7 19.3 63.5 AFF3 "LAF4, MLLT2-like" ENSG00000144218 "AF4/FMR2 family member 3" P51826 2 99545419-100192428 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 154.9;Excitatory neurons: 491.3;Inhibitory neurons: 300.7;Oligodendrocyte precursor cells: 211.6" "Group enriched" "Detected in many" 5 "breast cancer: 11.4;prostate cancer: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "memory B-cell: 31.0;naive B-cell: 44.2;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 17 "B-cells: 44.2;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "Daudi: 51.1;U-698: 56.5" "Low region specificity" "Detected in all" "HPA044512, HPA053379" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA044512: AB_10795984, HPA053379: AB_2682133" "unprognostic (1.05e-2)" "unprognostic (3.01e-2)" "unprognostic (2.30e-1)" "unprognostic (4.88e-3)" "unprognostic (1.02e-1)" "unprognostic (4.98e-5)" "unprognostic (1.11e-3)" "unprognostic (3.04e-2)" "unprognostic (8.75e-2)" "unprognostic (3.07e-1)" "unprognostic (1.95e-3)" "unprognostic (7.57e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (6.40e-3)" "unprognostic (6.79e-2)" "unprognostic (3.69e-2)" "unprognostic (7.87e-3)" 3.3 1.6 3.1 6.2 3.9 11.2 11.6 17.4 13.2 3.5 0.0 5.1 1.1 7.7 0.8 3.5 4.5 2.2 4.3 9.7 5.0 1.4 1.7 6.5 14.2 2.2 0.0 6.3 0.4 0.1 4.4 6.2 1.8 16.2 2.2 4.2 1.9 2.5 0.7 0.9 6.0 5.9 0.0 7.3 4.6 5.4 0.0 7.7 1.2 0.7 12.2 6.7 2.2 9.8 0.2 0.0 18.0 6.4 0.0 0.6 0.0 2.8 0.7 5.6 1.9 0.0 0.0 51.1 0.1 3.8 12.4 0.2 0.5 0.0 4.0 14.3 6.3 0.0 0.0 0.0 0.4 0.2 12.4 0.8 0.0 12.8 0.2 13.8 0.0 2.2 0.3 0.1 0.0 0.1 4.3 0.3 1.8 0.0 3.2 7.5 0.0 0.3 0.0 0.0 17.4 6.5 0.0 0.3 11.0 1.5 17.9 16.5 6.7 19.1 3.4 0.5 2.9 0.8 0.1 56.5 15.9 1.5 2.0 0.6 0.5 0.1 0.0 0.5 0.3 31.0 0.2 0.0 5.1 44.2 1.9 0.0 0.0 1.0 0.4 23.9 0.0 0.8 3.1 3.9 17.4 13.2 9.7 5.0 2.2 0.0 1.8 0.0 0.0 9.8 1.2 6.4 40.9 41.8 154.9 1.8 0.4 0.0 1.8 21.8 78.9 37.7 11.1 0.0 3.7 0.0 12.5 0.4 32.8 0.1 0.0 0.0 33.9 0.9 19.8 6.0 22.9 3.4 491.3 0.0 0.2 13.5 1.1 1.1 0.0 31.6 0.7 1.2 1.8 47.1 300.7 0.5 0.0 9.2 18.2 38.5 10.8 16.5 14.2 66.5 5.2 6.8 0.0 211.6 46.7 0.0 0.1 21.1 0.8 14.3 0.1 1.9 0.0 1.7 0.0 1.1 8.5 10.5 9.8 0.0 1.3 0.1 6.1 5.7 0.6 0.3 LONRF2 "FLJ45273, RNF192" ENSG00000170500 "LON peptidase N-terminal domain and ring finger 2" Q1L5Z9 2 100271875-100322501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 42.2;fallopian tube: 45.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 72.6;Excitatory neurons: 166.8;Horizontal cells: 111.0;Inhibitory neurons: 126.2;Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 15.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;GAMG: 7.3;HAP1: 5.8;HEK 293: 6.2;HMC-1: 5.1;PC-3: 5.3;SCLC-21H: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034595, HPA057366" Approved Approved Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA034595: , HPA057366: AB_2683420" "unprognostic (9.81e-2)" "unprognostic (4.97e-2)" "unprognostic (2.68e-2)" "unprognostic (3.20e-2)" "unprognostic (7.10e-2)" "unprognostic (7.72e-2)" "unprognostic (9.50e-2)" "unprognostic (9.86e-3)" "unprognostic (6.33e-2)" "unprognostic (1.32e-1)" "prognostic favorable (6.42e-5)" "unprognostic (1.14e-1)" "unprognostic (6.06e-2)" "unprognostic (3.45e-2)" "unprognostic (2.50e-2)" "unprognostic (2.66e-3)" "unprognostic (6.34e-2)" 3.2 31.9 20.1 0.5 20.0 0.1 3.2 7.6 25.5 11.6 5.8 5.6 0.5 26.4 42.2 2.6 45.6 2.3 6.4 26.7 40.4 2.2 1.0 1.8 0.5 2.6 3.3 24.3 6.3 9.6 18.0 0.7 9.9 4.1 0.7 11.2 2.4 4.0 7.1 1.1 1.6 28.2 0.2 0.8 4.6 2.2 27.4 0.4 4.9 4.1 0.3 4.2 3.7 9.9 0.0 6.0 1.8 2.1 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 1.1 0.0 1.0 0.0 7.3 0.0 5.8 0.0 0.0 0.5 6.2 0.0 0.4 0.0 0.2 0.1 5.1 0.0 0.0 0.2 0.0 0.4 0.0 1.6 3.5 0.1 0.0 4.0 0.0 0.3 0.3 1.1 5.3 0.0 0.0 0.0 1.4 0.2 12.5 3.4 0.0 0.0 0.8 1.9 3.2 0.0 0.1 0.0 0.7 0.0 0.4 0.0 0.0 0.0 2.4 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 20.1 20.0 7.6 25.5 26.7 40.4 2.6 3.3 9.9 0.2 27.4 9.9 0.5 0.0 11.7 52.5 0.5 0.8 1.4 0.0 1.2 72.6 5.1 2.3 37.4 8.6 3.1 5.5 31.3 2.3 0.1 0.3 5.9 3.7 0.6 22.5 43.6 1.8 11.4 2.7 166.8 2.2 0.2 12.7 4.1 37.1 5.7 25.8 0.0 0.6 0.4 111.0 126.2 0.5 0.0 0.0 1.2 2.3 3.4 0.6 1.8 7.5 0.0 8.4 0.0 58.3 38.7 1.5 0.1 11.7 0.1 4.9 0.0 0.3 3.4 20.6 6.6 3.3 5.3 0.8 0.6 0.8 0.1 2.9 1.6 0.9 0.4 0.4 CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 21.5;Muller glia cells: 16.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012884, HPA051545" Approved Approved Cytosol "Intracellular and membrane" NA NA 680000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA012884: AB_1846710, HPA051545: AB_2681529" "unprognostic (5.40e-3)" "unprognostic (3.62e-2)" "unprognostic (3.44e-2)" "unprognostic (2.03e-1)" "unprognostic (3.28e-1)" "unprognostic (1.30e-1)" "unprognostic (1.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.78e-1)" "unprognostic (4.54e-2)" "prognostic favorable (4.05e-4)" "unprognostic (8.02e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-2)" "unprognostic (3.73e-2)" "unprognostic (3.06e-2)" "unprognostic (3.27e-1)" 4.3 6.7 26.5 4.2 28.2 3.2 5.1 24.3 33.6 7.1 18.8 6.3 2.3 11.5 13.3 4.2 9.7 5.5 11.0 27.2 23.2 4.3 1.2 8.1 4.4 24.6 26.4 12.7 5.6 9.6 11.5 8.2 23.2 8.0 2.4 9.4 6.1 5.2 6.0 2.2 3.6 12.0 24.8 5.0 4.4 6.1 28.6 5.7 10.0 8.3 5.4 5.5 3.7 25.1 0.2 14.6 28.4 14.6 8.5 11.9 14.2 16.7 11.8 22.4 14.3 0.3 8.5 20.4 14.1 10.1 39.6 0.0 20.2 2.2 14.3 29.1 21.2 10.5 8.3 23.1 10.1 21.5 26.5 8.8 2.7 10.6 2.0 10.7 17.8 19.5 31.0 0.1 9.7 4.8 19.1 16.8 42.0 0.2 17.7 13.6 17.6 0.2 6.2 6.4 30.5 24.9 1.2 0.1 23.3 20.0 7.8 29.0 16.4 15.5 24.5 11.7 15.7 0.0 0.1 21.2 19.0 18.7 18.6 0.0 0.0 0.0 1.3 0.0 0.4 0.8 0.2 1.0 0.2 0.6 0.3 0.7 0.0 0.0 0.0 1.1 0.0 0.5 26.5 28.2 24.3 33.6 27.2 23.2 24.6 26.4 23.2 24.8 28.6 25.1 2.8 16.0 3.1 21.5 4.4 0.9 1.1 0.3 0.6 9.7 2.4 2.0 6.3 1.5 4.4 1.8 0.0 5.4 2.3 0.0 3.9 3.5 1.5 2.7 6.7 4.9 1.8 3.0 10.7 2.9 10.5 5.0 0.0 6.2 0.0 6.5 0.4 0.0 6.2 6.7 7.5 0.0 0.0 0.8 1.1 0.4 2.1 1.3 0.0 6.5 3.2 16.7 1.0 12.5 5.9 2.2 0.0 5.3 2.3 1.5 0.0 1.1 0.7 4.8 0.0 3.7 3.5 1.5 5.1 0.3 0.6 1.4 3.4 8.5 0.1 0.2 NMS ENSG00000204640 "Neuromedin S" Q5H8A3 2 100470482-100483280 "Predicted secreted proteins" Neuropeptide "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "medulla oblongata: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HL-60: 8.4;HMC-1: 4.8" "Group enriched" "Detected in some" 4 "basal ganglia: 2.4;hypothalamus: 5.4;pons and medulla: 1.3" "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.9 2.7 0.1 0.2 1.7 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA018469: AB_1855116, HPA027094: AB_10601387" "unprognostic (1.34e-1)" "unprognostic (8.30e-2)" "unprognostic (2.20e-1)" "unprognostic (3.32e-2)" "unprognostic (5.07e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.07e-5)" "unprognostic (1.44e-1)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.55e-5)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (8.22e-2)" "prognostic favorable (4.23e-4)" 20.8 22.0 19.1 27.1 21.6 22.9 23.0 21.6 24.3 18.9 16.6 27.3 17.0 24.1 37.2 36.8 22.5 21.3 30.6 18.4 21.3 28.4 18.5 18.4 25.3 21.8 24.7 21.1 11.4 23.4 10.5 23.4 21.7 27.0 28.9 21.1 16.9 23.2 58.8 36.8 17.3 38.6 20.8 17.0 17.6 22.8 22.1 22.4 21.4 34.3 34.0 33.1 17.5 22.2 41.8 58.7 59.9 52.2 19.3 27.4 67.5 51.3 32.5 92.9 58.1 74.2 25.5 68.6 74.0 62.3 122.3 34.2 76.0 50.2 74.0 110.6 65.8 72.0 31.8 89.7 50.8 77.3 73.2 29.8 92.0 82.0 52.3 24.2 58.9 52.8 61.1 43.8 70.7 74.6 75.8 117.7 77.9 45.6 86.6 72.5 63.2 48.0 58.2 98.7 55.9 49.6 41.0 54.7 59.0 48.6 42.3 53.0 45.8 56.4 60.1 44.8 72.2 26.4 54.1 68.3 34.4 90.5 45.7 82.3 64.8 80.2 63.1 124.4 72.8 92.5 95.0 70.4 114.9 78.1 97.7 75.4 7.0 93.9 161.7 64.0 113.6 87.3 19.1 21.6 21.6 24.3 18.4 21.3 21.8 24.7 21.7 20.8 22.1 22.2 37.4 19.2 25.2 1.6 39.5 65.6 36.6 79.2 52.9 13.0 24.8 36.2 40.9 18.6 46.1 14.7 6.2 70.8 61.5 16.0 60.7 50.6 37.0 38.9 26.6 30.2 19.8 21.7 2.3 39.1 51.2 22.6 19.4 34.6 92.9 25.4 12.5 17.0 59.7 11.8 2.0 24.0 89.5 17.8 80.7 14.3 14.6 54.4 35.6 3.7 104.3 19.7 40.2 2.0 4.5 31.8 18.6 33.4 27.7 33.2 19.7 77.9 28.1 16.5 52.6 23.8 54.1 5.5 66.9 63.2 57.5 52.4 91.8 24.5 31.3 32.4 NPAS2 "bHLHe9, MOP4, PASD4" ENSG00000170485 "Neuronal PAS domain protein 2" Q99743 2 100820139-100996829 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 112.6;Early spermatids: 65.1;Excitatory neurons: 150.5;Inhibitory neurons: 58.5;Microglial cells: 69.3;Oligodendrocyte precursor cells: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 142.8;PC-3: 110.3;RT4: 90.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA019674 Uncertain Supported Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 50: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA019674: AB_10601275" "unprognostic (2.74e-1)" "unprognostic (8.89e-2)" "unprognostic (4.66e-2)" "unprognostic (5.06e-3)" "unprognostic (4.39e-2)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.07e-4)" "unprognostic (5.47e-3)" "unprognostic (4.48e-1)" "unprognostic (1.56e-1)" "unprognostic (1.59e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (3.55e-7)" "unprognostic (7.03e-2)" "unprognostic (6.58e-2)" "unprognostic (7.71e-3)" "unprognostic (1.34e-3)" 9.6 12.5 17.9 6.0 19.5 0.1 9.5 1.9 17.6 14.5 3.2 15.6 20.9 13.5 2.9 50.3 10.9 9.9 29.2 16.5 8.4 23.0 23.6 7.9 2.3 6.7 10.6 3.9 39.5 1.2 14.9 5.3 5.2 17.3 11.1 6.2 18.2 4.4 22.0 28.1 17.3 9.1 6.0 5.9 24.0 11.1 18.0 1.2 9.6 7.7 5.0 28.3 22.2 11.3 13.4 74.1 0.1 0.9 69.9 30.1 10.6 24.4 72.2 9.8 21.1 1.3 6.0 0.0 28.5 4.0 142.8 0.6 10.8 18.1 10.2 0.9 4.2 0.0 13.7 34.6 33.1 0.0 3.0 25.6 28.7 23.9 38.3 39.8 41.0 7.8 0.3 0.2 8.0 27.1 5.1 0.6 1.3 21.8 110.3 0.3 1.6 0.8 51.0 90.4 0.2 1.4 0.1 4.4 54.8 0.8 0.7 0.8 15.8 7.3 9.6 14.6 10.7 0.0 0.0 0.1 77.3 0.1 12.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.0 17.9 19.5 1.9 17.6 16.5 8.4 6.7 10.6 5.2 6.0 18.0 11.3 1.2 0.0 11.4 112.6 0.4 3.8 8.6 12.0 3.4 6.4 9.0 10.2 16.0 21.5 8.8 12.9 0.0 0.8 0.2 32.6 0.0 12.9 65.1 10.1 5.7 7.1 9.1 0.0 150.5 15.6 1.0 5.7 24.5 22.0 0.0 3.7 21.4 14.4 0.1 28.6 58.5 8.9 6.1 0.3 1.0 14.0 7.2 0.7 3.6 69.3 0.8 3.2 0.0 58.3 4.2 14.3 15.5 5.3 0.1 27.3 30.5 11.3 6.0 0.6 0.0 4.8 3.9 0.6 3.5 9.6 6.5 0.3 1.3 5.5 12.4 39.1 RPL31 L31 ENSG00000071082 "Ribosomal protein L31" P62899 2 101002229-101024032 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072263 Approved NA NA 110000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "HPA072263: AB_2686502" "unprognostic (4.82e-3)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (1.86e-2)" "unprognostic (9.36e-2)" "unprognostic (3.32e-2)" "unprognostic (3.94e-2)" "unprognostic (8.43e-2)" "unprognostic (2.24e-2)" "unprognostic (5.69e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.08e-6)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" "unprognostic (2.35e-2)" "unprognostic (2.51e-2)" 2836.5 1934.3 1831.5 1386.1 1850.8 4256.9 3080.8 1746.6 2503.7 3518.1 1791.4 2505.6 1186.7 2435.5 1712.5 2918.7 2787.5 926.1 2000.5 1782.3 1807.5 2132.0 1653.2 1865.3 2372.9 1811.2 1791.3 5933.5 3677.5 1196.2 2117.3 1310.0 1804.2 2434.0 1371.4 636.0 2261.9 957.0 2619.9 3250.2 2054.7 1032.7 1858.5 2183.6 2282.1 766.8 1876.1 2235.6 1952.8 1399.7 2240.6 2587.6 3039.2 1851.7 2131.8 1223.9 2161.3 3354.1 4081.4 5576.9 4033.6 3365.3 2630.1 2057.6 1635.4 3869.0 2441.5 5448.6 2542.4 2168.0 2092.3 2298.5 2112.3 3408.0 2154.0 1942.4 3326.5 3222.5 3926.9 4547.4 3203.0 5735.5 2507.1 4590.2 5268.6 1810.4 4133.3 4419.6 2364.2 2877.4 3081.2 1252.2 2394.2 2822.0 4274.2 7185.2 4047.5 2859.0 1460.9 2363.2 3273.8 4437.9 3238.0 3345.3 2666.9 2906.1 1424.2 4883.1 6312.3 1954.6 2369.4 7643.6 3601.4 1663.1 2960.9 1965.0 2671.1 2618.3 3840.8 3720.7 2310.8 5301.1 1651.1 1913.5 3911.6 860.5 4359.8 2983.4 7228.7 8467.2 7801.4 6122.4 5140.0 7039.0 10632.6 8774.1 567.2 5348.4 2507.4 5182.9 5414.0 14433.2 1831.5 1850.8 1746.6 2503.7 1782.3 1807.5 1811.2 1791.3 1804.2 1858.5 1876.1 1851.7 371.3 1352.6 2182.1 17.3 2271.0 3559.8 3859.2 3734.6 1044.3 69.1 2577.6 1284.6 809.5 1870.1 2378.5 1259.8 33.3 4002.6 1393.0 1267.4 3644.9 2181.4 1237.0 750.6 1149.8 1613.1 1770.7 1556.4 23.5 4152.0 4687.5 1518.2 498.9 849.8 2176.4 458.5 2626.5 2193.9 2563.9 48.8 19.5 3731.2 1055.9 2680.9 4079.7 2108.6 4234.0 1331.1 2459.9 16.9 3560.2 409.0 3318.3 21.6 16.7 3288.7 2799.4 2097.7 609.8 3081.4 2175.4 4409.4 1292.7 99.5 1255.6 2624.5 1366.9 600.1 397.6 1504.9 4376.2 3853.0 2405.7 543.9 3818.3 3606.7 TBC1D8 "AD3, GRAMD8, HBLP1, VRP" ENSG00000204634 "TBC1 domain family member 8" O95759 2 101007228-101252866 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 30.1;non-classical monocyte: 38.2" "Lineage enriched" "Detected in many" 5 "monocytes: 38.2" "Cell line enhanced" "Detected in many" "ASC diff: 82.9;ASC TERT1: 57.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015211, HPA037496" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Nuclear speckles" "CAB015211: , HPA037496: AB_2675507" "unprognostic (1.82e-1)" "unprognostic (2.04e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (4.25e-3)" "unprognostic (3.98e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-2)" "unprognostic (2.74e-1)" "unprognostic (5.80e-2)" "unprognostic (2.38e-1)" "unprognostic (8.53e-2)" "unprognostic (1.82e-1)" "unprognostic (2.25e-2)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (6.73e-2)" "unprognostic (7.98e-3)" 17.3 6.3 4.7 8.9 4.4 12.7 21.8 8.7 5.0 14.4 8.3 9.0 7.1 10.6 7.8 15.4 19.9 18.1 38.6 5.1 6.3 17.0 24.8 23.2 7.2 6.8 5.3 8.4 34.3 17.5 13.0 3.1 6.7 44.0 6.0 6.5 19.0 30.3 83.7 28.1 28.7 6.9 4.3 14.5 27.2 18.1 5.9 6.4 9.6 79.7 6.8 13.1 17.5 4.1 5.1 30.1 2.6 8.6 82.9 57.8 24.4 3.1 51.8 2.1 2.6 10.8 8.0 2.6 27.1 2.3 42.5 15.5 5.0 23.5 1.4 1.5 4.6 1.5 11.1 37.7 5.7 0.3 26.0 27.4 21.8 2.8 21.6 1.7 30.2 4.5 0.7 2.6 2.7 13.3 2.8 15.8 6.7 3.6 32.3 6.4 7.5 0.6 17.0 32.3 18.7 9.2 4.2 7.4 10.8 4.0 2.1 23.1 26.0 1.3 4.5 4.4 2.1 5.0 0.4 0.2 10.9 7.7 8.0 0.0 9.7 0.4 0.2 30.1 0.3 0.4 0.3 0.2 5.0 1.5 0.6 0.4 0.3 0.0 38.2 7.2 0.2 4.1 4.7 4.4 8.7 5.0 5.1 6.3 6.8 5.3 6.7 4.3 5.9 4.1 4.3 3.2 4.6 10.7 2.8 4.1 38.3 7.2 23.9 6.4 15.0 3.9 12.2 18.6 14.4 5.5 4.2 4.6 4.8 1.1 0.0 8.2 6.0 42.6 4.7 9.8 3.0 0.8 43.5 3.0 2.8 4.3 31.6 23.7 7.0 0.9 11.7 5.6 3.7 1.7 42.8 2.2 10.2 13.8 17.7 10.9 3.1 27.7 5.4 22.5 28.1 1.0 0.0 23.6 6.5 2.6 2.4 1.9 1.4 35.0 4.8 1.2 31.9 3.7 6.6 24.7 4.3 3.6 4.0 29.8 6.3 3.4 1.6 2.7 1.1 29.7 CNOT11 "C2orf29, C40" ENSG00000158435 "CCR4-NOT transcription complex subunit 11" Q9UKZ1 2 101252886-101270316 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069823, HPA074943" Enhanced Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm "HPA069823: AB_2686209, HPA074943: " "unprognostic (1.72e-1)" "unprognostic (2.51e-1)" "unprognostic (5.43e-2)" "unprognostic (2.77e-2)" "unprognostic (2.02e-2)" "unprognostic (1.13e-3)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.78e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (8.33e-6)" "unprognostic (4.19e-2)" "unprognostic (2.35e-1)" "unprognostic (3.62e-3)" "unprognostic (2.72e-3)" 15.7 20.3 16.7 26.3 17.5 34.7 19.1 18.4 21.1 22.6 20.6 31.4 33.1 19.8 24.8 36.4 20.9 25.0 37.7 17.3 17.8 27.9 30.8 19.7 37.7 17.6 17.2 14.1 30.9 21.9 14.5 34.1 17.8 20.0 36.1 16.1 24.8 19.1 33.0 25.3 31.5 20.8 17.6 29.8 30.3 29.5 17.8 31.8 17.3 26.4 40.9 24.3 20.2 18.7 42.6 29.1 46.2 64.1 38.2 46.0 137.4 43.1 54.6 52.5 55.4 64.2 47.8 75.0 49.7 39.1 66.1 50.6 56.0 51.7 63.4 51.4 47.6 62.6 32.1 96.6 42.5 76.2 59.5 36.5 46.3 37.7 40.0 43.1 59.7 41.8 71.1 44.4 48.0 44.5 74.8 82.0 58.0 67.5 40.6 47.5 50.3 58.1 72.3 79.4 69.1 44.1 26.1 76.6 72.4 52.6 48.5 69.2 40.3 40.7 47.2 35.4 36.4 63.2 63.5 58.8 45.0 84.4 48.6 9.6 2.0 3.9 3.1 2.9 2.1 2.0 3.2 3.8 1.7 3.1 3.0 4.1 7.9 1.2 2.8 2.6 4.5 1.3 16.7 17.5 18.4 21.1 17.3 17.8 17.6 17.2 17.8 17.6 17.8 18.7 13.4 6.4 13.4 11.1 17.3 11.7 24.7 13.8 14.2 10.7 18.1 10.7 27.8 28.6 14.6 40.5 14.6 65.8 21.1 32.1 31.3 52.1 8.7 53.3 14.0 19.1 10.8 9.4 12.5 41.3 52.6 12.9 25.0 41.8 6.3 13.8 16.8 32.1 23.0 6.7 12.5 26.2 12.2 17.9 8.9 9.3 9.6 16.8 5.4 14.0 29.3 19.9 21.6 9.5 18.2 43.6 18.6 12.0 25.6 32.7 24.6 34.8 24.1 11.3 39.5 10.6 22.4 34.1 15.7 26.9 12.8 57.6 22.1 30.0 25.7 39.3 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 619.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 619.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" 26.7 15.2 7.7 40.3 7.5 52.3 16.3 7.7 9.7 17.7 12.3 15.7 16.8 12.4 16.3 35.5 16.9 18.9 12.5 7.6 8.9 16.3 26.6 30.5 18.3 9.9 8.5 15.9 22.3 17.9 10.4 21.8 9.6 12.6 15.8 7.8 18.3 10.1 8.5 25.6 18.2 12.9 8.5 53.1 19.1 15.8 9.1 15.2 12.2 9.4 19.6 29.1 22.7 10.9 19.9 11.4 8.8 11.3 31.6 31.3 49.7 24.0 31.8 32.1 35.8 29.0 51.6 6.1 28.3 23.9 42.9 39.0 12.5 24.6 29.7 16.9 16.6 12.4 9.9 50.0 42.1 13.4 19.2 28.9 40.0 37.9 25.1 24.7 58.9 13.0 10.7 18.0 32.4 16.9 18.8 14.0 6.1 27.1 20.0 11.5 14.2 23.4 38.0 48.0 11.5 8.5 14.4 36.0 37.2 9.5 9.7 17.8 39.6 16.2 9.1 24.5 5.3 35.5 22.5 0.2 5.2 18.6 12.2 44.0 73.6 90.3 43.8 118.1 41.8 13.2 40.0 45.3 27.9 8.5 28.2 30.2 619.9 15.3 134.1 52.5 53.8 69.8 7.7 7.5 7.7 9.7 7.6 8.9 9.9 8.5 9.6 8.5 9.1 10.9 19.9 48.1 48.1 44.7 55.2 76.9 78.1 63.5 54.7 20.4 29.7 15.9 13.0 41.5 48.4 55.2 56.3 65.2 112.4 53.1 1.9 59.1 97.9 41.8 31.9 30.0 8.5 22.7 82.8 42.2 73.0 53.5 37.2 63.1 39.2 17.3 27.1 46.2 85.9 8.4 71.6 31.7 12.2 278.6 144.2 37.2 30.7 209.0 40.9 50.6 116.5 11.6 61.8 34.7 59.6 54.3 52.3 19.5 125.5 73.5 45.9 25.8 44.8 20.7 59.2 40.5 30.1 36.6 40.3 128.3 91.6 128.1 115.7 23.8 32.8 154.1 CREG2 ENSG00000175874 "Cellular repressor of E1A stimulated genes 2" Q8IUH2 2 101345550-101387503 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "brain: 27.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 66.0;Inhibitory neurons: 27.6;Oligodendrocytes: 12.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 12 "amygdala: 8.7;basal ganglia: 17.2;cerebral cortex: 26.3;hippocampal formation: 27.8;white matter: 9.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;HaCaT: 6.3;HeLa: 2.5;OE19: 7.1;PC-3: 2.4;RT4: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA038224 Enhanced "Secreted in brain" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA038224: AB_10673167" "unprognostic (5.09e-2)" "unprognostic (3.78e-3)" "unprognostic (4.10e-3)" "unprognostic (8.15e-3)" "unprognostic (5.63e-3)" "unprognostic (9.68e-3)" "unprognostic (4.52e-8)" "unprognostic (3.86e-4)" "unprognostic (1.39e-1)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (7.69e-2)" "unprognostic (5.41e-3)" "unprognostic (4.44e-2)" "unprognostic (2.91e-1)" "unprognostic (8.26e-3)" "unprognostic (7.77e-2)" 0.0 0.1 8.7 0.0 17.2 0.1 0.0 0.0 26.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.1 27.8 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.2 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.7 9.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.1 2.4 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 8.7 17.2 0.0 26.3 27.8 0.0 1.3 0.0 0.6 0.0 1.4 9.0 0.0 0.0 0.0 2.9 0.0 0.0 0.6 0.5 0.0 0.8 0.1 0.1 0.9 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.2 0.0 0.5 0.0 0.0 66.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 27.6 0.1 2.0 0.0 0.0 6.5 0.0 0.2 0.0 6.5 0.0 0.8 0.0 2.5 12.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.5 0.0 0.2 0.1 1.5 5.6 0.5 0.0 0.1 0.0 0.2 0.0 1.5 RFX8 FLJ42986 ENSG00000196460 "Regulatory factor X8" Q6ZV50 2 101397359-101475112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 3.7" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Excitatory neurons: 11.5;Inhibitory neurons: 4.5;Late spermatids: 10.2;Spermatocytes: 8.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.6;hTEC/SVTERT24-B: 16.8;LHCN-M2: 6.9;U-87 MG: 9.6;U-937: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA059745 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nuclear bodies" "HPA059745: AB_2684120" "unprognostic (1.02e-1)" "unprognostic (1.88e-2)" "unprognostic (1.24e-1)" "unprognostic (5.55e-2)" "unprognostic (2.56e-3)" "unprognostic (8.14e-2)" "unprognostic (3.63e-2)" "unprognostic (6.04e-2)" "unprognostic (4.93e-2)" "unprognostic (9.55e-2)" "unprognostic (1.51e-2)" "unprognostic (4.76e-2)" "unprognostic (4.73e-5)" "unprognostic (4.96e-2)" "unprognostic (1.74e-1)" "unprognostic (3.14e-1)" "unprognostic (1.09e-2)" 0.6 0.1 0.0 0.1 0.0 3.7 0.8 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.7 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 5.6 0.0 2.1 1.7 1.3 1.7 0.0 3.2 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 2.0 0.0 16.8 0.1 0.0 0.0 0.6 0.0 0.0 6.9 0.0 0.7 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.2 0.2 0.0 1.9 3.1 0.0 0.0 0.0 9.6 4.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 1.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 16.6 1.4 0.1 1.0 0.0 0.0 11.5 0.0 0.7 2.6 0.0 0.5 0.0 0.1 0.7 0.0 0.1 0.0 4.5 0.0 0.0 0.3 1.6 10.2 0.3 0.4 0.0 2.8 0.0 0.0 0.0 0.5 1.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 1.3 8.5 1.5 0.0 0.0 1.4 0.1 0.0 0.0 0.1 MAP4K4 "FLH21957, HGK, NIK" ENSG00000071054 "Mitogen-activated protein kinase kinase kinase kinase 4" O95819 2 101696850-101894689 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 472.1" "Cell type enhanced" "Detected in many" "Microglial cells: 337.3;Oligodendrocytes: 1134.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008476 Uncertain NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA008476: AB_1079362" "unprognostic (6.40e-2)" "unprognostic (1.09e-2)" "unprognostic (4.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (1.57e-4)" "unprognostic (4.29e-2)" "unprognostic (9.79e-2)" "unprognostic (2.22e-3)" "unprognostic (8.65e-2)" "prognostic unfavorable (3.62e-6)" "unprognostic (6.67e-3)" "unprognostic (8.98e-2)" "unprognostic (3.15e-1)" "unprognostic (7.14e-3)" 54.1 9.1 272.6 42.9 316.1 72.5 32.2 208.8 252.5 23.9 95.0 21.1 10.6 27.4 12.1 35.2 19.7 34.5 44.8 219.4 256.3 15.0 32.8 29.2 54.1 317.5 286.1 23.1 16.1 15.0 10.0 49.4 273.1 13.9 17.8 22.7 19.3 10.2 37.4 21.1 17.7 28.7 246.7 24.2 22.0 40.1 348.5 44.3 15.8 30.6 60.1 33.1 25.6 472.1 112.7 83.8 175.2 84.3 162.4 288.6 219.5 139.8 114.3 122.2 100.1 139.5 145.6 163.1 118.3 210.3 36.0 45.5 56.0 123.2 121.1 219.8 38.0 122.4 62.5 367.7 136.7 59.1 5.5 261.3 55.3 301.9 133.5 122.1 322.5 90.3 80.9 0.4 325.4 61.3 137.8 36.5 89.2 42.5 131.5 164.1 120.0 0.6 81.2 38.8 68.5 113.6 96.5 0.4 104.0 160.8 22.4 105.1 409.1 240.5 102.9 70.6 168.6 0.3 0.4 96.7 155.2 73.2 180.1 8.8 3.2 0.0 2.3 3.2 1.6 3.4 2.9 1.5 1.1 5.0 2.2 2.5 13.5 1.1 3.1 6.0 3.7 1.5 272.6 316.1 208.8 252.5 219.4 256.3 317.5 286.1 273.1 246.7 348.5 472.1 104.3 19.2 23.9 283.0 64.5 30.0 41.9 17.4 12.5 109.1 14.3 17.4 71.0 28.6 29.6 18.4 50.1 13.1 38.4 12.0 0.0 57.4 31.5 67.2 77.1 84.2 17.4 48.0 197.5 53.2 23.4 49.7 26.5 101.0 24.0 151.8 67.1 39.2 38.8 35.3 122.4 13.6 14.2 26.9 245.9 46.0 55.0 54.7 19.6 337.3 88.0 49.2 10.3 228.7 1134.5 128.1 12.0 17.3 18.0 72.1 5.3 6.3 22.9 10.4 52.6 65.2 73.3 29.0 82.1 24.3 24.6 7.8 38.4 17.2 14.4 40.4 IL1R2 "CD121b, IL1RB" ENSG00000115590 "Interleukin 1 receptor type 2" P27930 2 101991960-102028544 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 90.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 495.7;Kupffer cells: 207.9;Langerhans cells: 1083.3;Macrophages: 210.8;Pancreatic endocrine cells: 211.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 16.1" "Group enriched" "Detected in some" 6 "cerebral cortex: 6.4;pons: 1.9" "Immune cell enriched" "Detected in some" 26 "neutrophil: 377.5" "Lineage enriched" "Detected in many" 26 "granulocytes: 377.5" "Cell line enriched" "Detected in some" 8 "HDLM-2: 469.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA027597, HPA027598" Uncertain "Secreted to blood" NA NA 7130000 27000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA027597: AB_10600768, HPA027598: AB_10601229" "unprognostic (3.54e-2)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (3.83e-2)" "unprognostic (6.59e-2)" "unprognostic (1.42e-1)" "unprognostic (6.36e-2)" "unprognostic (4.82e-3)" "unprognostic (1.62e-2)" "unprognostic (7.15e-2)" "unprognostic (8.20e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.58e-12)" "unprognostic (1.92e-1)" "unprognostic (7.51e-2)" "unprognostic (1.77e-1)" "unprognostic (6.62e-2)" 19.7 5.9 0.2 35.5 0.7 52.8 3.7 0.3 6.4 10.3 1.9 29.7 0.8 2.5 3.5 41.2 17.7 5.3 4.0 0.2 0.5 16.0 11.6 30.8 3.3 0.5 0.4 1.2 3.7 0.3 0.8 20.1 1.9 2.3 43.7 0.1 7.9 2.2 1.2 30.7 4.6 3.4 0.3 90.1 33.0 0.5 0.7 7.4 1.9 2.9 38.5 6.2 20.5 0.3 7.3 0.9 0.0 0.0 0.9 1.2 0.8 0.0 0.2 0.0 0.1 7.7 0.2 0.1 14.7 0.0 0.3 2.9 0.0 0.5 0.0 469.8 0.4 0.1 0.1 4.0 2.5 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 60.4 0.0 0.0 0.0 0.0 24.0 1.7 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.4 0.0 1.1 0.4 7.2 0.2 0.0 0.3 0.0 0.5 0.2 0.0 0.1 4.3 0.0 0.0 2.3 0.0 0.0 0.9 0.0 14.5 0.0 0.0 0.0 377.5 0.2 0.1 0.2 5.9 1.5 0.2 0.7 0.3 6.4 0.2 0.5 0.5 0.4 1.9 0.3 0.7 0.3 1.2 6.4 1.1 0.0 1.7 147.9 13.5 2.0 495.7 0.0 0.5 0.4 0.6 10.0 0.3 1.8 0.0 1.2 1.2 23.8 5.9 15.0 2.8 14.5 1.5 4.4 6.7 2.7 0.0 8.3 36.3 6.1 18.3 8.0 2.5 0.0 3.6 16.2 5.8 0.0 0.0 117.4 0.0 207.9 1083.3 4.0 0.3 210.8 32.0 0.0 3.5 0.0 0.0 0.0 0.0 211.0 26.8 0.0 1.6 20.4 0.0 0.7 2.2 0.0 6.6 0.7 3.8 0.7 2.2 38.1 84.0 27.8 2.7 0.4 26.8 14.4 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1RL2 "IL1R-rp2, IL1RRP2" ENSG00000115598 "Interleukin 1 receptor like 2" Q9HB29 2 102187006-102240002 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 12.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 5.6;Excitatory neurons: 9.7;Glandular and luminal cells: 8.4;Langerhans cells: 7.1;Suprabasal keratinocytes: 5.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.1;ASC TERT1: 5.1;HaCaT: 3.8;HSkMC: 4.4;hTCEpi: 2.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hippocampal formation: 1.0" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.57e-2)" "unprognostic (2.76e-4)" "unprognostic (3.42e-3)" "unprognostic (2.60e-1)" "unprognostic (3.13e-3)" "unprognostic (6.79e-2)" "unprognostic (9.10e-3)" "unprognostic (9.17e-2)" "unprognostic (4.61e-2)" "unprognostic (2.38e-1)" "unprognostic (1.05e-2)" "unprognostic (8.33e-3)" "unprognostic (3.80e-1)" "unprognostic (1.47e-1)" "unprognostic (7.65e-2)" 1.0 1.5 0.5 0.5 0.6 0.3 2.6 0.1 0.9 1.5 0.0 0.9 0.1 0.4 1.4 5.8 2.3 2.3 0.5 0.7 1.0 4.3 2.9 0.5 0.0 0.8 0.5 0.3 0.5 2.6 0.3 0.3 0.8 0.9 1.1 0.0 2.2 2.3 0.4 12.3 0.3 0.3 0.1 0.1 1.6 0.1 0.9 0.3 2.4 0.7 1.0 1.0 2.5 0.3 8.1 0.0 0.0 0.0 1.5 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 3.8 0.0 0.6 0.4 0.4 0.0 0.0 1.1 0.0 1.5 0.0 0.0 4.4 2.3 1.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.9 0.7 1.0 0.8 0.5 0.8 0.1 0.9 0.3 1.1 0.0 1.1 0.3 0.0 5.6 2.7 0.7 3.4 0.0 2.1 2.4 0.3 1.5 0.4 1.8 0.0 0.1 0.2 0.5 3.9 0.2 0.3 3.8 2.4 0.9 1.2 0.0 9.7 0.2 0.2 1.4 0.5 8.4 0.0 0.0 0.0 1.3 0.6 0.0 1.1 1.1 0.0 2.8 7.1 0.2 1.5 4.2 0.0 1.9 0.6 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 2.0 0.0 0.4 0.1 0.0 0.0 1.8 1.7 0.0 0.0 5.2 5.5 0.1 0.2 0.6 0.7 1.8 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 24.2;lymphoid tissue: 18.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.7;granulocytes: 111.2;Langerhans cells: 25.4;NK-cells: 42.2;T-cells: 25.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 27.4;HHSteC: 35.4;U-937: 52.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA007615 Approved Approved Mitochondria Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "HPA007615: AB_1851675" "unprognostic (3.60e-3)" "unprognostic (9.75e-3)" "unprognostic (1.12e-3)" "unprognostic (3.01e-2)" "unprognostic (2.34e-3)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.74e-2)" "unprognostic (3.59e-1)" "unprognostic (7.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (4.52e-4)" "unprognostic (2.62e-1)" "unprognostic (1.62e-2)" "unprognostic (5.71e-2)" "unprognostic (2.48e-2)" 8.2 2.3 1.3 5.6 1.4 2.4 5.4 1.2 1.9 4.5 1.6 4.0 4.1 3.1 1.6 2.2 3.7 2.9 4.5 1.0 2.4 4.4 6.6 24.2 4.1 1.5 1.3 1.1 1.3 3.2 1.7 6.9 1.8 3.3 1.0 0.2 2.2 5.7 0.9 2.6 8.8 0.7 1.3 18.5 4.3 0.5 2.0 2.0 2.1 1.1 2.2 4.0 2.8 1.3 1.8 0.6 0.0 0.0 1.3 0.8 2.3 0.0 1.1 0.1 0.5 0.0 0.8 0.0 0.1 0.0 3.4 0.9 0.0 2.4 0.0 27.4 1.2 2.1 0.5 0.1 35.4 8.8 10.1 7.8 1.9 3.1 5.4 0.0 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 1.4 1.1 0.0 0.0 0.0 0.3 0.9 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.8 0.9 0.5 3.2 0.6 0.0 0.0 0.0 0.1 52.0 3.6 10.0 0.0 4.8 6.2 0.1 16.3 0.1 3.6 4.7 3.6 0.2 0.6 1.4 6.7 45.6 0.0 10.4 4.1 1.9 1.3 1.4 1.2 1.9 1.0 2.4 1.5 1.3 1.8 1.3 2.0 1.3 10.2 0.0 8.5 0.3 2.7 0.8 1.1 1.1 0.6 0.0 0.3 0.3 3.9 0.0 2.3 1.8 0.0 0.0 44.7 0.3 1.9 0.9 0.1 1.0 4.1 7.4 0.0 3.6 0.2 0.6 1.0 3.1 5.1 1.1 111.2 0.0 10.0 7.6 0.1 0.0 1.0 0.1 0.0 2.4 25.4 0.1 0.3 16.5 3.6 12.2 1.0 0.2 42.2 1.5 0.0 1.1 0.4 0.0 10.3 1.0 0.1 0.9 3.8 0.2 6.6 0.9 1.4 0.4 1.3 0.3 1.0 0.0 25.4 0.1 0.4 0.9 IL18RAP "AcPL, CD218b" ENSG00000115607 "Interleukin 18 receptor accessory protein" O95256 2 102418689-102452565 "CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 104.6;lymphoid tissue: 46.7" "Group enriched" "Detected in some" 6 "dendritic cells: 42.2;NK-cells: 66.9;T-cells: 22.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "NK-cell: 118.1" "Group enriched" "Detected in many" 107 "granulocytes: 67.6;NK-cells: 118.1;T-cells: 65.2" "Cell line enriched" "Detected in some" 11 "U-937: 54.1" "Not detected" "Not detected" "Not detected" "Not detected" CAB025270 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB025270: " "unprognostic (1.73e-3)" "unprognostic (6.27e-3)" "unprognostic (5.07e-3)" "unprognostic (4.64e-6)" "unprognostic (2.90e-1)" "unprognostic (1.18e-2)" "unprognostic (5.86e-5)" "unprognostic (5.09e-3)" "unprognostic (4.02e-2)" "unprognostic (1.57e-3)" "unprognostic (4.78e-2)" "unprognostic (5.31e-2)" "unprognostic (1.51e-2)" "unprognostic (2.71e-1)" "unprognostic (6.35e-2)" "unprognostic (8.56e-2)" "unprognostic (2.73e-2)" 6.8 0.6 0.4 12.0 0.4 104.6 1.5 0.3 1.1 0.7 0.7 2.0 2.3 0.5 0.3 1.1 5.5 3.0 1.6 0.3 0.4 1.5 3.5 16.2 2.6 0.4 0.4 0.4 0.6 0.1 0.6 1.4 0.7 1.1 1.7 0.0 0.8 0.6 0.5 0.4 6.3 1.0 0.5 46.7 2.6 0.1 0.6 0.8 1.1 1.1 2.8 2.5 1.3 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.1 2.2 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.1 0.3 0.2 0.1 19.3 46.2 0.1 65.2 0.0 5.9 12.6 0.5 0.0 0.2 1.5 67.6 118.1 0.0 0.7 0.4 6.4 0.4 0.4 0.3 1.1 0.3 0.4 0.4 0.4 0.7 0.5 0.6 0.4 0.4 3.2 1.1 0.0 0.8 0.3 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.3 1.1 0.1 1.3 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.8 5.3 0.0 0.0 1.9 0.0 1.9 0.6 0.0 66.9 0.0 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 22.5 0.0 0.0 0.0 SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 53.8" "Group enriched" "Detected in some" 12 "Collecting duct cells: 25.8;Gastric mucus-secreting cells: 54.0" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;OE19: 6.8;RT4: 4.1" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Low region specificity" "Detected in single" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" 0.0 0.0 0.4 0.1 0.5 0.8 0.2 0.7 0.7 0.3 0.0 0.0 2.0 0.1 0.1 1.5 0.1 1.2 0.6 0.4 0.4 8.6 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 1.3 0.5 1.4 0.4 0.0 0.0 0.0 0.2 53.8 0.3 0.2 0.1 0.1 0.0 0.5 0.4 0.1 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 1.3 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.5 6.8 0.2 0.0 0.2 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.7 0.7 0.4 0.4 0.1 0.1 0.2 0.0 0.2 0.6 0.0 3.2 3.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.0 0.9 25.8 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 54.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.1 0.4 0.0 0.3 0.3 SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;stomach 1: 26.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 41.3;Early spermatids: 46.5;Gastric mucus-secreting cells: 41.8;Intestinal goblet cells: 23.4;Late spermatids: 31.4;Paneth cells: 38.7;Undifferentiated cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.0;OE19: 37.3;RT4: 16.9;SK-BR-3: 14.7;T-47d: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" 0.0 0.1 1.4 2.1 0.7 0.0 1.4 0.8 1.5 1.4 0.2 20.0 6.3 0.1 3.9 0.3 0.3 1.1 0.0 1.9 0.9 5.4 0.0 0.1 0.1 1.4 0.7 0.0 0.0 5.8 1.0 0.0 1.5 5.8 20.7 0.1 4.9 2.1 6.4 0.8 3.4 0.7 0.8 0.0 26.4 5.7 1.2 0.4 1.0 6.2 4.5 1.0 0.0 0.5 10.0 6.1 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.2 0.0 3.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 3.4 2.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 7.7 0.0 0.1 0.2 37.3 5.0 0.0 0.1 0.0 1.1 16.9 0.1 0.0 0.0 14.7 0.0 0.0 18.5 0.0 0.0 0.0 0.7 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.8 1.5 1.9 0.9 1.4 0.7 1.5 0.8 1.2 0.5 0.0 0.0 0.0 2.0 0.3 0.4 0.2 0.1 0.0 0.0 1.1 0.1 0.8 0.0 0.3 9.2 0.0 0.5 0.0 41.3 0.0 0.2 46.5 0.5 0.2 0.3 9.7 0.0 3.0 0.0 0.0 0.0 41.8 3.1 0.0 0.0 0.0 0.0 0.1 0.0 14.6 23.4 6.1 0.0 0.4 31.4 0.6 0.0 0.0 5.6 0.0 0.5 0.0 1.0 1.0 8.5 38.7 0.0 0.2 4.1 3.2 1.4 0.1 0.1 0.0 0.5 0.1 4.5 0.2 0.0 0.6 0.3 0.2 0.0 29.6 0.8 MFSD9 MGC11332 ENSG00000135953 "Major facilitator superfamily domain containing 9" Q8NBP5 2 102714630-102736888 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055293, HPA061859" Approved Approved "Nucleoli,Nucleoli rim" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Nucleoli rim" "HPA055293: AB_2682775, HPA061859: AB_2684627" "unprognostic (1.27e-2)" "unprognostic (5.07e-2)" "unprognostic (5.00e-2)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.38e-4)" "unprognostic (2.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.32e-1)" "unprognostic (2.60e-2)" "unprognostic (2.98e-1)" "unprognostic (1.06e-1)" "unprognostic (8.42e-2)" "unprognostic (6.88e-3)" "unprognostic (1.94e-1)" "unprognostic (2.16e-1)" "unprognostic (3.33e-1)" "unprognostic (2.28e-2)" 2.8 2.2 1.4 2.9 1.4 4.1 2.6 4.3 2.0 3.6 1.8 6.4 8.7 1.8 2.8 4.5 1.8 2.3 1.4 1.9 1.7 4.6 10.5 2.2 3.2 1.4 1.6 2.4 9.2 4.1 3.4 2.4 1.5 2.6 5.8 2.4 4.9 3.1 1.3 2.9 7.2 1.9 1.3 2.7 4.7 1.2 1.7 4.5 2.9 1.2 3.6 3.3 2.2 1.2 3.1 2.4 3.0 5.2 3.6 1.6 6.1 1.9 1.9 2.8 2.8 8.6 4.1 2.7 3.1 1.2 4.3 4.7 4.8 1.8 1.8 11.5 4.4 4.5 3.1 10.9 3.0 3.6 6.2 1.6 6.1 1.7 0.9 2.9 1.8 8.8 2.7 1.3 1.4 2.9 3.7 7.2 2.3 7.4 3.1 2.8 4.9 2.8 5.9 9.4 5.8 4.1 1.7 6.1 6.9 3.2 2.3 5.7 1.3 1.9 4.0 3.2 2.7 3.6 2.9 1.8 2.1 8.4 2.6 1.3 0.3 1.5 1.2 0.6 0.9 0.8 0.9 0.8 0.6 0.6 0.9 1.1 1.0 1.0 0.5 1.2 0.7 0.7 1.4 1.4 4.3 2.0 1.9 1.7 1.4 1.6 1.5 1.3 1.7 1.2 1.6 0.0 1.5 1.0 4.1 3.3 3.2 3.7 2.8 1.5 4.1 1.3 3.1 1.5 5.4 7.3 4.2 8.2 4.3 15.9 0.0 5.8 12.8 3.3 2.0 1.6 3.0 1.7 5.4 8.6 9.1 3.3 7.1 5.3 3.8 3.0 1.4 11.5 4.8 0.0 12.2 8.7 10.2 2.9 1.4 4.5 0.9 2.6 0.0 1.9 4.3 1.4 7.2 4.0 1.3 11.4 8.0 1.2 8.9 4.2 10.4 3.6 3.9 2.8 6.6 2.1 2.4 1.0 5.3 4.3 4.4 11.5 5.1 3.1 7.2 8.2 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 POU3F3 "BRN1, OTF8" ENSG00000198914 "POU class 3 homeobox 3" P20264 2 104853287-104858574 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 45.6;epididymis: 32.4;kidney: 58.8;seminal vesicle: 15.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 58.8;Distal tubular cells: 27.4;Proximal tubular cells: 13.2" "Group enriched" "Detected in some" 6 "glioma: 21.5;renal cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 59.6;AN3-CA: 53.9;HEK 293: 21.2;RPTEC TERT1: 57.3;SH-SY5Y: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052792, HPA056039, HPA067151" Enhanced Enhanced Nucleoplasm NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA052792: AB_2681951, HPA056039: AB_2683018, HPA067151: AB_2685790" "unprognostic (3.05e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (4.26e-5)" "unprognostic (9.66e-2)" "unprognostic (1.97e-1)" "unprognostic (4.69e-1)" "unprognostic (1.16e-1)" "unprognostic (7.28e-2)" "unprognostic (1.15e-3)" "unprognostic (7.15e-2)" 1.5 0.1 22.5 0.1 36.9 0.0 0.3 34.6 36.2 0.0 0.0 0.7 0.0 0.0 32.4 0.0 0.0 0.0 0.1 26.3 18.9 58.8 0.0 0.0 0.0 31.0 35.5 0.1 0.0 0.0 0.1 0.0 25.3 0.2 0.2 0.3 1.3 15.2 0.0 1.7 0.1 0.0 22.7 0.0 0.6 0.2 30.6 0.2 0.0 0.0 0.1 0.0 0.0 45.6 0.0 0.0 59.6 53.9 0.6 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.4 0.0 0.0 0.0 6.5 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 1.8 1.7 0.0 0.0 0.9 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.7 0.5 0.0 0.1 0.0 6.4 1.4 0.0 57.3 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 36.9 34.6 36.2 26.3 18.9 31.0 35.5 25.3 22.7 30.6 45.6 0.0 0.0 0.0 1.0 0.5 0.8 0.1 0.0 0.0 3.8 0.0 0.6 1.0 0.0 0.0 58.8 0.0 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.2 5.4 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 13.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria "HPA043476: AB_2678498, HPA048479: AB_2680412" "unprognostic (8.10e-3)" "unprognostic (4.75e-3)" "unprognostic (3.69e-1)" "unprognostic (3.80e-3)" "unprognostic (5.25e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.88e-1)" "unprognostic (1.16e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (3.78e-1)" "unprognostic (2.62e-3)" "unprognostic (4.62e-2)" "unprognostic (5.28e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" 17.2 33.5 21.4 17.9 22.7 24.6 23.3 24.1 26.5 18.3 25.7 29.8 29.5 20.7 19.2 23.8 24.2 13.4 64.1 21.4 23.3 32.7 31.8 15.4 24.7 24.0 22.8 30.8 24.2 32.8 19.6 12.9 24.3 23.4 33.3 22.3 23.3 21.6 98.6 21.9 23.4 19.8 22.7 18.5 25.9 33.5 22.8 30.8 21.4 97.0 27.1 20.2 17.9 25.1 68.2 28.9 59.4 55.1 30.6 31.5 69.6 42.6 40.6 66.2 59.2 155.0 46.4 70.6 41.1 33.9 68.9 59.8 118.0 62.1 69.9 44.0 77.5 69.7 42.4 94.4 51.0 52.2 29.9 37.9 41.5 54.6 45.4 38.3 51.6 84.8 101.5 35.9 45.7 54.9 70.6 68.6 93.9 57.4 62.6 88.9 50.9 98.3 83.2 47.3 51.4 30.9 49.4 71.5 59.9 58.0 58.9 52.2 34.0 38.8 78.2 38.9 46.6 32.6 41.5 56.3 33.6 79.1 33.3 21.7 23.8 10.1 39.3 31.5 43.3 44.4 43.0 41.7 43.0 35.3 42.9 42.4 2.8 46.0 39.9 32.1 49.9 31.7 21.4 22.7 24.1 26.5 21.4 23.3 24.0 22.8 24.3 22.7 22.8 25.1 18.2 22.4 28.2 28.1 21.0 19.5 25.3 56.4 22.2 24.7 15.4 22.2 110.2 22.8 30.4 22.0 12.5 39.9 29.1 17.7 107.6 40.7 51.7 35.9 18.6 22.5 19.7 47.5 43.4 42.7 40.7 21.2 18.8 12.9 22.8 34.6 18.2 31.2 28.8 8.4 54.2 27.9 24.4 15.2 9.9 14.6 23.9 15.9 30.2 17.8 26.2 21.2 29.9 49.3 69.4 22.6 18.3 27.1 25.0 17.4 23.1 72.3 42.1 32.0 39.5 24.8 28.1 112.8 40.7 23.4 13.2 20.4 25.2 62.9 40.5 19.0 GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.2" "Group enriched" "Detected in some" 51 "Early spermatids: 4.2;Late spermatids: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "BEWO: 1.3;U-2 OS: 4.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 9: U-2 OS - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "HPA055940: AB_2682977" "unprognostic (3.80e-3)" "unprognostic (5.92e-2)" "unprognostic (2.19e-3)" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.96e-1)" "unprognostic (1.61e-3)" "unprognostic (1.11e-2)" "unprognostic (3.13e-4)" "unprognostic (2.25e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.5 0.1 0.1 0.0 0.0 0.6 0.9 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.7 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.8 0.6 1.5 0.6 0.9 0.9 0.5 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TGFBRAP1 "TRAP-1, TRAP1, VPS3" ENSG00000135966 "Transforming growth factor beta receptor associated protein 1" Q8WUH2 2 105264391-105329735 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037672, HPA038397" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA037672: AB_2675597, HPA038397: AB_10669782" "unprognostic (1.66e-1)" "unprognostic (1.58e-2)" "unprognostic (8.99e-2)" "unprognostic (4.49e-3)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (5.63e-3)" "unprognostic (9.15e-2)" "unprognostic (2.25e-1)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (8.30e-2)" "unprognostic (8.82e-2)" "unprognostic (3.89e-1)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" 9.6 8.1 6.5 8.0 6.3 22.7 8.1 6.1 7.2 6.6 7.7 8.1 7.2 7.8 5.4 8.3 7.0 5.9 6.6 6.8 5.4 6.7 5.0 7.4 9.4 5.8 6.4 7.6 9.9 11.4 5.1 10.4 5.9 8.3 8.2 6.2 8.3 9.3 11.8 11.1 8.0 8.9 5.6 8.5 13.5 2.5 6.5 9.1 10.9 7.7 8.3 7.8 6.6 7.2 22.5 17.5 12.5 15.5 13.3 10.5 25.4 16.0 21.8 26.6 25.3 25.9 13.6 22.7 16.9 18.2 27.1 13.5 22.4 38.1 21.9 24.3 23.8 30.7 13.8 20.7 12.1 28.6 22.4 12.7 22.5 22.2 19.6 14.1 28.7 19.5 28.0 10.9 32.6 14.9 20.4 18.3 15.9 15.4 14.5 22.9 19.8 33.0 16.4 27.3 24.7 16.5 13.2 26.1 25.8 9.0 13.1 17.5 20.8 16.7 25.4 14.1 16.4 11.3 14.8 24.7 11.9 19.6 35.3 0.4 0.8 1.1 1.8 0.7 1.5 0.6 1.2 1.0 0.6 1.0 0.7 1.1 0.3 0.9 0.5 1.0 0.9 0.7 6.5 6.3 6.1 7.2 6.8 5.4 5.8 6.4 5.9 5.6 6.5 7.2 13.7 6.4 9.5 10.4 8.1 8.0 3.5 5.6 9.1 12.4 8.8 9.3 5.9 5.7 7.1 5.5 16.7 12.4 8.9 7.5 1.9 5.4 0.1 5.2 7.0 10.6 11.3 11.3 17.0 10.8 4.8 8.5 9.7 8.3 2.5 10.8 13.9 6.7 12.9 15.2 14.8 8.2 8.2 13.8 4.4 0.5 7.5 9.9 3.6 17.8 9.5 9.0 11.3 8.5 13.5 8.3 5.2 8.2 7.6 7.7 5.8 7.3 2.7 7.2 26.3 15.8 8.1 0.4 1.2 11.5 13.1 7.4 8.8 11.1 9.2 3.1 C2orf49 "asw, MGC5509" ENSG00000135974 "Chromosome 2 open reading frame 49" Q9BVC5 2 105337532-105349211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043846, HPA060814" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Mitochondria "HPA043846: AB_2678698, HPA060814: AB_2684372" "unprognostic (4.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.06e-1)" "unprognostic (6.16e-3)" "unprognostic (2.57e-3)" "unprognostic (8.75e-3)" "unprognostic (1.89e-3)" "unprognostic (6.51e-2)" "unprognostic (5.01e-2)" "unprognostic (2.07e-1)" "unprognostic (2.56e-1)" "unprognostic (5.94e-2)" "prognostic unfavorable (5.06e-5)" "unprognostic (1.22e-1)" "unprognostic (1.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.04e-2)" 11.3 9.3 9.6 10.6 11.9 19.3 11.1 12.0 12.9 12.5 6.2 9.1 9.4 14.6 7.8 11.8 12.4 9.5 15.3 8.9 10.7 8.7 10.1 8.6 12.6 11.2 11.5 19.9 11.0 10.5 5.5 12.0 11.3 11.3 9.9 24.9 9.1 11.0 19.9 9.5 10.1 12.2 10.2 11.1 13.8 13.0 10.6 16.0 12.6 21.0 13.3 11.3 10.5 13.8 20.0 13.9 17.2 17.5 19.4 23.6 30.7 19.6 20.6 17.0 23.3 30.7 19.5 23.3 23.9 17.1 45.6 18.7 23.9 16.7 22.2 30.6 18.1 25.3 11.6 23.8 23.6 21.3 20.1 17.1 28.7 24.0 21.6 24.3 15.8 18.1 35.9 18.7 24.3 15.4 25.9 24.5 22.6 13.5 16.8 17.1 25.4 27.1 19.2 18.9 20.3 16.2 17.3 15.5 23.8 19.2 15.2 23.8 25.4 17.9 25.1 13.0 16.1 23.6 20.5 24.6 18.1 21.3 17.6 15.4 13.2 12.0 9.0 8.3 8.9 14.5 10.1 9.0 9.2 17.6 11.0 9.3 17.8 9.2 11.9 19.1 12.7 6.7 9.6 11.9 12.0 12.9 8.9 10.7 11.2 11.5 11.3 10.2 10.6 13.8 27.0 16.0 14.3 7.5 26.3 29.1 13.4 21.8 15.4 37.1 24.8 22.9 30.9 18.6 22.0 25.8 29.2 21.2 31.6 16.5 25.4 22.9 40.6 43.1 34.7 19.3 11.3 21.2 10.8 18.2 26.5 22.8 12.8 33.9 16.5 18.1 19.6 22.4 16.1 23.5 11.2 22.5 12.2 18.5 13.5 35.8 27.7 15.5 7.2 10.3 21.1 39.6 28.8 7.1 15.8 21.0 17.5 29.0 19.0 16.2 21.8 22.3 36.1 44.3 19.7 17.3 19.8 45.8 28.1 13.7 24.7 36.8 22.4 16.6 14.8 15.8 FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1421.4;ovary: 535.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1077.5;Extravillous trophoblasts: 585.9;Granulosa cells: 851.4;Leydig cells: 567.0;Peritubular cells: 1049.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.7" "Group enriched" "Detected in many" 6 "granulocytes: 5.7;T-cells: 2.7" "Cell line enhanced" "Detected in many" "LHCN-M2: 534.6;RPTEC TERT1: 489.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 14000 "Cluster 18: Basophils - Vesicular transport" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments, Focal adhesion sites" "CAB008368: AB_591383, HPA005922: AB_1078860, HPA006028: AB_1078858" "unprognostic (1.04e-1)" "unprognostic (1.63e-3)" "unprognostic (3.30e-1)" "unprognostic (3.42e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (2.01e-4)" "unprognostic (2.80e-2)" "unprognostic (1.02e-3)" "unprognostic (1.81e-1)" "unprognostic (2.42e-2)" "unprognostic (3.34e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (6.42e-5)" "unprognostic (2.06e-1)" "unprognostic (3.49e-1)" "unprognostic (9.92e-3)" "unprognostic (4.73e-2)" 68.3 70.2 10.4 28.9 13.2 17.0 65.4 7.6 18.2 101.9 15.0 75.2 48.5 105.1 33.8 55.4 55.8 81.5 1421.4 18.9 7.4 55.2 22.1 17.5 17.2 6.7 7.2 535.4 9.1 8.2 29.3 79.3 7.0 88.8 56.8 8.5 45.3 63.8 67.5 44.2 50.4 91.5 7.5 20.1 94.9 50.9 7.9 22.8 41.3 118.6 13.9 105.5 47.2 12.2 156.8 36.1 20.9 0.8 65.2 81.7 196.4 289.3 75.9 182.2 216.7 65.6 237.6 0.4 23.7 353.6 223.8 47.7 31.4 262.4 204.2 6.5 23.9 108.7 42.9 49.0 257.6 0.4 23.5 171.7 142.2 286.0 188.1 360.8 374.4 18.0 29.0 8.9 534.6 5.6 25.8 1.0 44.1 108.3 113.2 0.4 31.6 4.3 489.8 108.4 1.0 6.9 109.2 48.1 76.9 20.5 60.7 3.9 183.1 130.4 134.1 146.4 236.0 3.3 0.6 0.7 208.1 0.6 138.5 5.7 0.4 0.4 1.1 0.2 0.7 0.6 0.9 2.0 0.4 0.5 0.7 1.5 2.2 0.7 0.2 0.6 2.7 1.5 10.4 13.2 7.6 18.2 18.9 7.4 6.7 7.2 7.0 7.5 7.9 12.2 15.7 9.6 5.1 0.7 1.0 468.5 1077.5 342.5 389.9 9.5 59.8 126.2 362.1 15.7 91.0 29.5 2.1 220.4 1.7 212.6 3.9 100.7 5.7 44.8 40.4 27.4 58.2 63.5 46.3 117.9 585.9 96.1 186.1 32.5 10.2 851.4 17.2 9.2 25.3 0.0 4.9 169.8 73.2 0.6 31.8 17.3 567.0 10.4 23.2 25.3 2.7 1.6 0.0 0.5 1.6 234.5 258.2 1049.0 6.7 198.2 51.7 28.1 19.1 13.0 216.9 60.6 171.0 9.1 17.7 124.5 296.9 178.7 7.7 193.5 55.8 536.2 NCK2 NCKbeta ENSG00000071051 "NCK adaptor protein 2" O43639 2 105744912-105894274 "Plasma proteins, Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 184.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016116, HPA031004" Approved NA NA 87000 "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 24: Non-specific - Transcription regulation" "CAB016116: AB_2150588, HPA031004: AB_10795571" "unprognostic (2.39e-1)" "unprognostic (3.48e-1)" "unprognostic (6.67e-2)" "unprognostic (4.43e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (5.85e-3)" "unprognostic (4.04e-2)" "unprognostic (4.88e-2)" "unprognostic (1.22e-1)" "unprognostic (9.62e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (8.24e-2)" "unprognostic (2.14e-2)" "unprognostic (7.21e-3)" "unprognostic (4.22e-2)" 37.8 19.7 18.6 20.5 19.2 17.6 33.6 26.3 29.0 36.4 16.7 39.1 54.7 29.7 18.9 68.8 25.4 19.0 31.9 27.9 18.4 28.9 11.1 37.1 27.6 21.8 22.4 25.1 39.8 13.6 19.7 36.8 22.0 24.7 16.4 10.3 46.8 18.7 53.5 33.4 51.7 17.9 22.5 52.0 40.3 27.3 23.9 18.6 28.3 27.2 19.1 35.6 50.4 20.4 25.8 20.2 51.6 23.9 15.0 10.7 73.3 19.0 25.0 21.6 12.5 58.8 20.9 11.2 23.4 24.2 31.0 25.1 21.9 47.7 14.6 79.5 24.5 5.0 9.4 37.8 39.2 28.1 9.8 21.4 34.0 23.5 30.0 18.7 22.0 27.3 7.7 38.5 17.9 21.7 29.3 48.2 28.8 21.6 23.0 23.4 36.2 41.7 28.1 51.2 32.9 45.4 14.4 37.2 184.4 30.4 13.6 70.3 25.0 37.9 55.2 1.0 27.2 28.8 19.6 3.8 16.7 24.5 61.6 26.2 1.0 12.5 7.0 1.0 9.2 7.7 13.1 11.8 1.2 11.1 13.6 12.5 9.3 11.9 1.0 1.8 24.5 5.0 18.6 19.2 26.3 29.0 27.9 18.4 21.8 22.4 22.0 22.5 23.9 20.4 41.8 16.0 7.9 28.1 32.8 17.6 13.9 14.2 7.4 13.5 27.1 35.9 21.3 71.4 9.6 16.5 12.5 39.0 30.3 31.2 7.9 28.1 15.5 18.0 21.8 23.7 19.2 2.5 60.0 18.8 15.2 16.2 13.3 19.9 5.7 33.0 18.2 2.3 26.0 82.4 48.4 23.1 18.3 14.2 13.9 9.2 23.6 18.7 10.6 77.8 10.5 61.4 18.6 24.6 18.3 29.9 29.2 28.2 15.8 17.7 51.3 8.4 18.9 4.6 32.9 33.1 54.4 4.2 9.6 10.7 16.8 29.7 52.4 18.1 31.2 30.0 ECRG4 "augurin, C2orf40" ENSG00000119147 "ECRG4 augurin precursor" Q9H1Z8 2 106063246-106078155 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 225.3" "Cell type enhanced" "Detected in some" "Adipocytes: 87.6;Fibroblasts: 25.3;Smooth muscle cells: 19.1" "Cancer enriched" "Detected in many" 11 "thyroid cancer: 72.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 8.5;naive CD8 T-cell: 7.2" "Lineage enriched" "Detected in single" 83 "T-cells: 8.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008546 Uncertain "Secreted to blood" NA NA 330000 "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: Fibroblasts - ECM organization" "HPA008546: AB_2066524" "prognostic favorable (4.58e-4)" "unprognostic (3.91e-1)" "unprognostic (2.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.09e-1)" "unprognostic (2.32e-1)" "unprognostic (1.61e-3)" "unprognostic (6.56e-3)" "unprognostic (1.82e-2)" "unprognostic (1.25e-1)" "unprognostic (2.35e-3)" "unprognostic (1.36e-2)" "unprognostic (1.06e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (9.11e-3)" "unprognostic (1.30e-4)" 66.7 27.6 5.3 1.1 6.0 0.0 49.6 9.6 5.3 73.8 225.3 47.6 5.3 24.6 28.4 20.2 47.5 9.4 25.7 12.0 13.0 47.1 3.2 27.6 1.7 14.9 21.5 13.2 5.9 0.7 96.2 8.5 15.4 55.1 5.6 0.1 20.4 101.8 10.3 14.1 19.2 9.0 19.4 25.8 165.8 27.0 12.2 2.8 101.1 6.9 0.3 79.6 58.2 11.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 2.0 1.3 0.0 0.0 8.5 7.2 0.0 0.0 0.0 0.0 0.8 1.4 5.3 6.0 9.6 5.3 12.0 13.0 14.9 21.5 15.4 19.4 12.2 11.7 87.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 UXS1 "FLJ23591, SDR6E1, UGD" ENSG00000115652 "UDP-glucuronate decarboxylase 1" Q8NBZ7 2 106093308-106194301 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 323.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008825 Uncertain "Intracellular and membrane" NA NA 24000 "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA008825: AB_1858708" "unprognostic (4.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.63e-2)" "unprognostic (3.92e-2)" "prognostic unfavorable (5.45e-4)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.20e-3)" "unprognostic (2.07e-1)" "prognostic favorable (7.94e-4)" "unprognostic (3.95e-2)" "unprognostic (1.40e-2)" "unprognostic (8.46e-2)" "unprognostic (3.96e-2)" "unprognostic (6.18e-2)" "unprognostic (1.86e-2)" "unprognostic (5.32e-2)" 16.3 17.6 20.4 25.0 18.7 40.4 15.3 30.4 29.3 19.6 20.6 21.7 15.5 24.3 33.1 24.1 29.2 19.6 29.3 25.9 20.3 60.0 15.7 46.0 27.9 15.0 23.0 24.4 15.8 37.3 16.3 54.6 19.3 23.2 24.0 10.5 14.6 25.9 31.9 14.0 14.3 21.4 18.5 25.0 26.2 31.9 31.0 22.2 30.0 28.6 30.4 29.5 18.3 23.7 66.5 48.8 50.9 39.0 88.4 65.2 110.2 71.4 66.9 49.9 61.5 96.9 110.4 12.0 87.0 74.1 111.2 32.8 22.6 58.2 54.5 64.2 40.5 37.0 21.4 110.6 34.9 30.5 39.0 42.8 63.8 50.3 33.5 57.5 52.5 22.8 22.1 28.5 103.6 46.8 34.3 66.8 60.1 64.2 65.4 70.3 38.6 34.3 323.0 60.9 16.7 19.0 51.5 45.7 44.3 67.7 17.0 93.7 48.0 55.1 58.5 45.4 45.4 34.4 51.4 17.9 55.0 70.1 103.8 11.3 24.7 28.5 23.1 20.8 25.7 15.3 64.3 41.4 19.1 30.5 68.8 49.1 6.1 37.5 16.0 13.5 130.4 44.3 20.4 18.7 30.4 29.3 25.9 20.3 15.0 23.0 19.3 18.5 31.0 23.7 15.4 89.8 88.8 18.9 22.1 16.8 26.8 117.3 14.8 9.9 11.6 10.5 18.7 17.2 61.6 86.5 4.2 71.2 17.7 20.5 50.9 46.9 80.2 41.5 19.3 25.5 6.6 12.0 49.8 25.0 74.1 34.2 16.8 40.6 29.8 13.1 10.8 15.0 33.2 8.4 37.5 15.6 34.6 20.1 12.5 18.5 15.2 33.9 14.2 33.7 56.2 10.8 18.6 24.1 11.7 30.4 16.2 12.8 10.2 35.7 9.6 17.5 38.8 7.9 19.7 19.0 35.1 17.0 81.6 22.6 13.2 24.6 33.7 51.6 18.0 19.8 RGPD3 RGP3 ENSG00000153165 "RANBP2 like and GRIP domain containing 3" A6NKT7 2 106391290-106468413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.9" "Cell type enriched" "Detected in some" 4 "Early spermatids: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 1.5;MOLT-4: 4.6;RPMI-8226: 1.4" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "unprognostic (6.61e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (6.86e-2)" "unprognostic (3.10e-1)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.44e-1)" "unprognostic (4.74e-3)" "unprognostic (5.05e-2)" "unprognostic (3.70e-1)" "unprognostic (3.42e-1)" "unprognostic (1.34e-1)" 0.2 0.1 0.4 0.1 0.4 0.4 0.2 0.4 0.5 0.1 0.9 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 0.4 0.7 0.7 0.2 0.1 1.0 0.6 0.2 0.2 0.2 0.5 0.2 1.1 0.2 0.1 0.9 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.6 0.1 6.9 0.7 1.9 0.1 0.1 0.2 0.3 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.6 0.1 0.2 0.1 0.0 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.4 0.3 0.0 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.5 0.4 0.4 1.0 0.6 1.1 0.4 0.7 0.5 0.0 0.0 1.1 1.6 0.1 0.1 0.1 0.0 0.0 1.6 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.1 0.1 0.5 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.3 4.4 0.0 0.1 0.0 1.9 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.4 3.2 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CD8B2 CD8BP ENSG00000254126 "CD8b2 molecule" A6NJW9 2 106487364-106544297 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.7;lymphoid tissue: 7.4" "Cell type enhanced" "Detected in some" "Proximal tubular cells: 2.9;T-cells: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory CD8 T-cell: 18.8;naive CD8 T-cell: 30.7" "Lineage enriched" "Detected in many" 14 "T-cells: 30.7" "Cell line enriched" "Detected in some" 8 "RPMI-8226: 390.6" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (9.34e-3)" "unprognostic (7.84e-2)" "unprognostic (2.32e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-1)" "unprognostic (5.54e-2)" "unprognostic (1.18e-1)" "unprognostic (5.27e-1)" "unprognostic (1.28e-2)" "unprognostic (1.21e-1)" "unprognostic (2.27e-1)" "unprognostic (2.76e-2)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (6.90e-2)" "unprognostic (9.67e-3)" 0.0 0.0 2.2 0.5 2.0 0.0 0.1 2.1 2.7 0.4 1.5 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 1.9 1.9 2.0 0.0 0.0 2.0 3.5 2.6 0.0 0.0 0.3 0.0 3.7 0.7 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.0 2.3 0.1 0.8 0.1 3.0 7.4 0.0 0.0 5.6 0.7 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 51.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 390.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 12.0 42.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.6 0.0 2.8 0.0 0.0 18.8 0.0 0.0 0.1 30.7 0.1 0.2 0.0 0.0 0.0 11.8 2.2 2.0 2.1 2.7 1.9 1.9 3.5 2.6 3.7 2.3 3.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 ST6GAL2 "KIAA1877, SIAT2, St6GalII" ENSG00000144057 "ST6 beta-galactoside alpha-2,6-sialyltransferase 2" Q96JF0 2 106801600-106887108 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.0;thyroid gland: 28.7" "Group enriched" "Detected in some" 4 "Astrocytes: 58.8;Excitatory neurons: 78.7;Granulosa cells: 111.5;Inhibitory neurons: 44.8;Oligodendrocyte precursor cells: 94.0" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 16.0" "Group enriched" "Detected in many" 77 "amygdala: 6.9;basal ganglia: 7.4;cerebral cortex: 11.0;hippocampal formation: 10.8;thalamus: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.3;hTERT-RPE1: 6.4;NTERA-2: 4.4;PC-3: 5.9;RPMI-8226: 9.6;SCLC-21H: 6.1;U-138 MG: 7.5;U-266/70: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014459 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA014459: AB_1857528" "unprognostic (2.08e-1)" "unprognostic (5.80e-2)" "unprognostic (1.55e-1)" "unprognostic (4.63e-2)" "unprognostic (6.44e-3)" "unprognostic (1.62e-1)" "unprognostic (2.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.29e-4)" "unprognostic (4.56e-3)" "unprognostic (7.04e-2)" "unprognostic (1.84e-2)" "unprognostic (7.01e-4)" "unprognostic (4.70e-4)" "unprognostic (4.06e-2)" "unprognostic (2.83e-1)" "unprognostic (2.07e-2)" 0.5 0.1 6.9 0.2 7.4 1.0 0.7 0.0 11.0 1.7 0.0 1.1 0.2 2.6 0.3 1.8 0.7 5.1 0.5 10.8 0.0 0.4 2.6 0.6 0.3 0.0 0.0 0.6 0.1 0.1 0.1 1.5 0.0 0.8 2.3 1.9 0.8 0.8 0.1 0.7 0.4 2.0 0.0 0.1 0.6 5.3 4.6 0.1 28.7 0.0 0.3 0.6 1.0 0.1 0.0 5.3 2.8 0.0 0.0 0.0 0.1 0.2 0.0 1.2 0.3 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.9 0.0 6.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.4 0.0 5.9 0.0 0.0 9.6 0.2 0.0 6.1 3.9 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.5 0.1 0.2 0.0 9.9 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 6.9 7.4 0.0 11.0 10.8 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.0 0.0 58.8 0.0 0.9 0.2 0.0 18.8 6.6 0.2 3.4 1.4 0.0 0.6 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.4 0.8 12.2 0.3 1.2 6.3 78.7 0.0 0.0 1.7 0.0 0.5 0.0 111.5 2.2 0.0 0.2 0.0 44.8 3.3 0.0 0.0 0.0 1.2 0.3 0.1 0.0 2.8 0.0 0.9 0.0 94.0 1.9 0.0 1.0 0.7 0.0 0.3 0.0 0.6 0.0 0.5 0.0 0.2 2.9 0.1 1.1 4.3 0.0 0.3 0.1 0.1 3.2 0.0 RGPD4 "DKFZp686P0288, RGP4" ENSG00000196862 "RANBP2 like and GRIP domain containing 4" Q7Z3J3 2 107826892-107892544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.7" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 5.8;Early spermatids: 10.4;Late spermatids: 3.1;Spermatocytes: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (4.96e-2)" "unprognostic (3.04e-1)" "unprognostic (4.38e-1)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (1.29e-1)" "unprognostic (3.05e-3)" "unprognostic (7.79e-2)" "unprognostic (1.52e-1)" "unprognostic (4.47e-1)" "unprognostic (6.05e-2)" "unprognostic (2.69e-2)" 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.2 0.8 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.1 1.0 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.3 3.7 0.5 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.2 0.5 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.3 0.0 0.3 0.2 0.0 0.1 0.3 0.1 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 SLC5A7 "CHT1, hCHT" ENSG00000115665 "Solute carrier family 5 member 7" Q9GZV3 2 107986523-108013994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter biosynthesis, Sodium transport, Symport, Transport" "Congenital myasthenic syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 32.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Club cells: 3.1;Respiratory ciliated cells: 1.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "RT4: 3.6;SCLC-21H: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 23.1;hypothalamus: 9.0;midbrain: 9.4;pons and medulla: 14.4;thalamus: 6.2" "Group enriched" "Detected in many" 6 "basal ganglia: 20.4;pons: 26.5;spinal cord: 46.7" HPA046105 Approved "Nuclear bodies,Cell Junctions,Intermediate filaments" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 15: RT4 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Intermediate filaments" "Nuclear bodies" "HPA046105: " "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-3)" "unprognostic (7.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-4)" "unprognostic (1.05e-2)" "unprognostic (9.78e-3)" "unprognostic (6.42e-2)" "unprognostic (1.61e-2)" 0.1 0.7 1.1 0.5 3.0 0.0 0.1 0.0 10.3 0.7 1.0 2.6 0.7 0.1 0.1 0.3 0.1 0.1 0.3 0.2 5.3 0.3 0.0 0.2 0.0 20.2 21.2 0.2 0.1 0.0 0.0 0.0 32.9 0.3 0.7 0.9 0.3 1.1 0.0 0.0 0.8 0.7 2.8 0.0 0.5 0.1 1.6 0.0 1.2 0.1 0.0 1.3 0.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 10.3 0.2 5.3 20.2 21.2 32.9 2.8 1.6 7.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 SULT1C3 ENSG00000196228 "Sulfotransferase family 1C member 3" Q6IMI6 2 108239971-108265351 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 83 "breast: 368.4" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "breast cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 36.7" HPA060368 Approved Cytosol NA NA "Cluster 5: Breast - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "HPA060368: " "unprognostic (1.14e-3)" "unprognostic (1.78e-1)" "unprognostic (4.13e-1)" "unprognostic (6.64e-2)" 0.1 0.0 0.1 0.0 0.1 0.0 368.4 0.0 0.1 0.1 1.6 0.4 3.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SULT1C2 "ST1C1, SULT1C1" ENSG00000198203 "Sulfotransferase family 1C member 2" O00338 2 108288639-108309915 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 70.3;stomach 1: 163.3" "Cell type enriched" "Detected in many" 7 "Gastric mucus-secreting cells: 553.0" "Cancer enhanced" "Detected in many" "renal cancer: 10.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "RPTEC TERT1: 25.4;RT4: 7.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007190 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA007190: AB_1857647" "unprognostic (3.31e-2)" "unprognostic (1.63e-2)" "unprognostic (3.41e-1)" "unprognostic (2.14e-2)" "unprognostic (2.55e-1)" "unprognostic (3.33e-2)" "unprognostic (1.17e-3)" "unprognostic (3.61e-2)" "unprognostic (3.78e-1)" "unprognostic (3.62e-2)" "unprognostic (8.74e-2)" "unprognostic (2.76e-1)" "unprognostic (3.19e-2)" "unprognostic (9.27e-2)" "unprognostic (6.28e-2)" "unprognostic (4.63e-2)" "unprognostic (9.96e-5)" 0.7 0.0 0.2 0.6 0.2 0.0 0.9 0.2 0.6 2.4 7.5 2.5 29.2 0.5 15.9 0.3 2.0 6.2 1.1 0.5 0.2 70.3 2.8 2.2 1.8 0.3 0.4 0.2 5.3 5.9 2.9 1.3 0.6 0.5 5.2 0.0 1.4 0.9 0.6 0.1 3.3 0.8 0.2 0.5 163.3 0.1 0.7 0.4 19.4 0.6 0.8 0.7 0.5 1.2 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.8 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.2 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.3 0.0 25.4 7.3 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.5 0.2 0.3 0.4 0.6 0.2 0.7 1.2 7.0 3.2 14.1 0.3 1.0 1.5 1.6 0.0 0.0 0.9 0.3 0.1 2.2 15.7 3.1 20.2 2.1 0.3 0.0 3.9 58.7 7.6 0.1 5.7 0.8 4.8 0.0 0.0 0.4 0.2 0.3 2.6 553.0 5.6 1.3 0.2 3.3 0.9 18.6 1.7 0.2 6.4 12.2 0.3 5.4 0.2 0.0 2.7 0.0 3.7 0.1 0.1 0.0 0.0 0.1 6.2 6.8 0.0 2.0 2.8 9.6 73.4 1.0 1.5 0.0 2.9 1.2 0.7 0.3 0.0 1.8 0.1 1.1 0.1 4.9 1.3 SULT1C4 "SULT1C, SULT1C2" ENSG00000198075 "Sulfotransferase family 1C member 4" O75897 2 108377911-108388989 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 13.3;Cholangiocytes: 37.1;Endothelial cells: 13.2;Granulosa cells: 15.3;Hepatic stellate cells: 17.9;Muller glia cells: 12.3;Oligodendrocyte precursor cells: 17.6" "Group enriched" "Detected in many" 6 "glioma: 7.1;renal cancer: 20.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.5;HUVEC TERT2: 10.7;SH-SY5Y: 42.0;SuSa: 11.6" "Low region specificity" "Detected in many" HPA034530 Approved Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA034530: AB_10670170" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-1)" "unprognostic (5.54e-2)" "unprognostic (1.06e-1)" "unprognostic (3.35e-2)" "unprognostic (5.77e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-3)" "prognostic favorable (9.99e-7)" "unprognostic (1.79e-2)" "unprognostic (2.96e-2)" "unprognostic (1.85e-2)" "unprognostic (1.38e-1)" 6.2 2.0 15.5 1.1 16.1 0.5 5.2 16.9 17.2 21.9 12.9 3.4 1.5 11.1 8.0 2.3 9.3 27.1 10.9 13.6 18.9 18.2 3.7 10.3 1.8 18.8 27.3 27.9 2.9 1.0 5.2 13.0 20.4 6.6 2.2 8.6 1.6 8.9 3.1 0.7 3.2 5.5 18.1 1.4 2.0 1.4 19.0 5.0 4.5 6.2 1.3 3.8 5.3 15.8 0.0 0.1 9.5 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.0 1.2 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 42.0 0.0 0.0 0.0 11.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 15.5 16.1 16.9 17.2 13.6 18.9 18.8 27.3 20.4 18.1 19.0 15.8 13.3 0.0 0.5 10.4 0.0 0.3 0.7 0.0 0.0 2.0 0.4 0.3 0.7 37.1 0.0 9.2 0.0 0.3 0.0 0.0 0.0 0.3 5.9 10.9 3.1 13.2 0.0 2.7 0.6 0.2 0.1 4.9 0.0 3.8 0.0 15.3 17.9 0.0 0.9 1.7 0.5 0.0 0.0 1.3 1.0 1.1 1.5 0.4 0.0 7.5 0.1 12.3 0.0 17.6 0.4 0.1 0.0 4.5 1.4 0.7 0.0 7.7 0.0 1.0 0.0 1.4 1.8 0.6 0.7 0.0 0.4 0.3 0.2 7.2 0.0 0.2 GCC2 "GCC185, KIAA0336" ENSG00000135968 "GRIP and coiled-coil domain containing 2" Q8IWJ2 2 108449191-108509415 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035849, HPA035850" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" Nucleoplasm "HPA035849: AB_10671941, HPA035850: AB_2674821" "unprognostic (1.35e-1)" "unprognostic (1.29e-2)" "unprognostic (2.45e-2)" "unprognostic (2.04e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (1.59e-1)" "unprognostic (3.11e-2)" "unprognostic (2.02e-1)" "unprognostic (1.06e-1)" "unprognostic (6.53e-2)" "unprognostic (6.53e-3)" "unprognostic (3.99e-1)" "unprognostic (4.71e-1)" "unprognostic (9.61e-2)" "unprognostic (1.64e-2)" 9.0 12.7 3.4 17.6 5.1 25.2 17.4 0.0 5.5 12.5 26.2 19.2 21.7 15.3 41.7 7.5 15.0 21.4 8.4 3.2 3.8 16.6 10.7 14.8 21.5 2.5 4.2 15.5 12.5 15.0 4.1 13.7 2.8 19.6 20.8 17.3 15.2 17.1 2.3 7.9 22.9 9.4 0.9 18.8 26.4 16.6 1.4 18.9 20.5 9.4 16.3 14.1 3.6 6.0 12.5 10.4 12.6 5.5 14.2 22.6 27.4 17.6 26.8 9.2 12.9 18.4 17.2 14.9 22.3 16.0 16.7 10.4 10.0 14.1 15.8 16.9 13.6 18.7 16.3 15.8 12.7 26.4 14.3 29.1 13.3 23.1 16.3 20.0 13.6 13.9 25.3 12.4 17.4 7.1 13.6 18.1 21.9 11.5 12.0 11.7 17.9 16.1 12.2 20.1 13.6 12.5 21.1 16.7 18.7 18.2 8.3 12.8 21.3 13.3 20.2 12.4 6.7 18.0 26.9 18.2 17.2 7.0 9.8 47.3 8.9 25.9 25.5 8.0 25.1 27.0 28.2 27.8 7.3 24.3 38.2 33.5 35.6 14.9 17.6 31.8 23.0 8.2 3.4 5.1 0.0 5.5 3.2 3.8 2.5 4.2 2.8 0.9 1.4 6.0 92.6 150.6 103.3 44.1 125.2 23.8 68.6 54.8 29.6 155.9 60.3 57.5 85.6 75.8 95.7 104.8 139.7 44.2 157.6 152.1 50.9 114.5 73.9 253.3 85.1 68.1 85.6 39.5 104.9 81.6 56.3 74.2 65.7 118.6 82.2 113.9 65.0 36.7 37.0 70.7 73.6 152.6 52.9 49.8 39.3 39.9 71.4 66.0 33.8 62.8 88.5 59.0 134.9 50.8 66.1 116.1 125.2 82.8 108.7 91.7 134.0 63.1 259.7 127.2 52.6 61.4 66.2 163.0 120.7 21.0 17.5 65.0 139.1 138.0 88.3 114.5 LIMS1 "PINCH, PINCH1" ENSG00000169756 "LIM zinc finger domain containing 1" P48059 2 108534355-108687246 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 379.6;Macrophages: 405.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 402.5" "HPA058455, HPA061230" Approved Approved "Focal adhesion sites,Cytosol" NA NA 10000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723, HPA061230: AB_2684456" "unprognostic (1.79e-1)" "unprognostic (8.82e-3)" "unprognostic (5.66e-2)" "unprognostic (1.17e-2)" "unprognostic (1.52e-1)" "unprognostic (4.23e-2)" "unprognostic (1.08e-3)" "unprognostic (1.09e-1)" "unprognostic (8.96e-2)" "unprognostic (1.18e-1)" "unprognostic (5.95e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.88e-4)" "unprognostic (7.51e-2)" "unprognostic (8.60e-3)" "unprognostic (1.43e-2)" "unprognostic (2.11e-1)" 41.0 45.0 7.0 33.8 10.4 32.9 28.9 9.4 8.4 22.7 10.8 22.1 16.7 35.8 11.6 26.9 31.5 31.2 38.0 6.9 11.4 16.7 20.1 37.0 37.9 12.9 11.0 20.5 15.0 12.0 8.0 32.2 12.8 19.5 18.0 11.5 17.6 26.7 99.1 14.2 20.0 35.8 11.3 21.0 22.2 16.8 15.0 21.4 24.8 35.8 32.8 30.0 17.6 15.9 44.7 49.0 19.0 22.8 30.8 44.5 91.6 49.0 56.0 37.1 37.6 85.3 93.7 43.1 145.4 63.0 55.0 28.3 29.0 50.2 49.3 106.7 52.0 225.6 32.1 45.8 70.4 42.7 402.5 43.5 45.5 98.3 80.3 44.2 135.9 37.3 81.0 58.2 115.4 36.5 41.4 31.4 37.5 29.0 49.6 52.2 65.9 35.0 70.2 79.5 34.3 46.3 76.6 32.5 34.5 25.0 16.8 39.6 184.2 166.6 75.6 37.5 101.2 56.4 81.6 60.6 139.3 47.6 43.6 211.9 69.6 196.2 16.6 119.3 30.5 18.7 72.3 22.4 59.4 18.0 19.2 7.3 31.6 35.9 156.2 7.7 89.0 140.3 7.0 10.4 9.4 8.4 6.9 11.4 12.9 11.0 12.8 11.3 15.0 15.9 143.5 99.3 55.6 80.6 43.2 74.1 63.0 65.1 63.7 26.2 34.9 37.0 61.6 38.6 53.4 29.5 54.2 45.1 40.6 19.2 39.2 80.9 22.5 266.8 122.9 187.6 118.1 84.5 32.6 233.5 130.3 109.4 32.6 379.6 101.4 107.0 76.1 34.6 189.0 15.2 34.6 24.0 48.8 181.1 265.4 12.0 81.4 405.4 44.4 115.2 118.5 69.2 41.2 54.3 66.8 122.3 17.2 88.0 76.3 82.1 33.5 44.0 84.8 18.8 65.7 116.2 161.2 45.4 51.1 75.2 77.0 27.9 82.4 51.3 32.4 66.4 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 CCDC138 FLJ32745 ENSG00000163006 "Coiled-coil domain containing 138" Q96M89 2 108786757-108885477 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 154.1;Excitatory neurons: 56.5;Inhibitory neurons: 58.9;Oligodendrocytes: 48.7;Respiratory ciliated cells: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049899, HPA054223" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA049899: AB_2680941, HPA054223: AB_2682420" "unprognostic (2.34e-1)" "unprognostic (3.74e-2)" "unprognostic (3.22e-2)" "unprognostic (3.04e-1)" "unprognostic (2.83e-2)" "unprognostic (1.64e-2)" "unprognostic (2.24e-5)" "unprognostic (2.89e-1)" "unprognostic (1.01e-4)" "unprognostic (2.56e-1)" "unprognostic (1.64e-1)" "unprognostic (5.77e-2)" "unprognostic (7.06e-4)" "unprognostic (7.88e-2)" "unprognostic (4.73e-2)" "unprognostic (2.69e-1)" "unprognostic (8.93e-2)" 1.0 0.9 2.0 2.0 1.8 3.5 2.4 4.8 3.1 1.3 2.1 1.9 1.0 2.1 1.3 2.1 4.3 1.8 0.7 2.4 2.3 1.7 2.8 1.3 4.5 2.6 2.4 1.6 1.7 0.7 0.8 1.3 2.4 1.4 2.3 2.3 1.3 0.7 1.0 2.4 1.7 1.5 2.0 1.2 1.8 10.9 2.0 6.4 0.8 0.7 3.8 1.6 1.3 3.0 14.7 6.7 22.4 11.6 1.8 2.0 14.2 6.3 2.0 14.6 10.6 21.8 8.4 35.2 9.2 2.0 7.3 12.2 16.3 8.5 13.0 8.2 21.0 16.3 11.6 18.2 2.2 22.4 2.3 1.4 2.5 17.2 5.1 2.2 7.7 15.0 31.4 15.8 7.5 8.2 32.2 15.3 33.3 8.0 6.9 21.1 21.2 21.3 8.1 11.5 15.7 15.3 13.6 7.3 11.1 13.6 7.8 10.7 4.9 9.2 16.2 6.0 13.5 4.9 12.2 36.4 3.8 17.2 9.3 2.6 0.5 0.8 1.1 1.2 2.2 3.0 1.5 2.3 0.5 3.2 2.2 2.6 0.3 2.0 0.4 4.8 2.4 1.2 2.0 1.8 4.8 3.1 2.4 2.3 2.6 2.4 2.4 2.0 2.0 3.0 2.4 0.0 3.3 14.7 7.9 2.4 3.5 4.5 6.8 7.3 3.6 3.9 1.4 2.8 9.6 1.8 8.4 5.2 13.6 0.9 1.9 3.7 154.1 38.9 7.0 2.7 5.4 5.9 56.5 1.4 5.5 6.3 8.6 7.3 4.5 6.7 1.1 2.4 2.2 6.7 58.9 2.5 2.0 1.6 1.5 34.0 3.7 3.9 1.8 10.3 1.3 1.8 6.2 19.1 48.7 3.3 0.5 1.9 14.4 1.1 0.7 1.7 43.8 7.0 0.0 5.0 3.5 29.5 20.1 7.0 2.8 1.4 5.9 5.5 2.9 2.3 EDAR "DL, ED1R, ED3, ED5, EDA1R, EDA3" ENSG00000135960 "Ectodysplasin A receptor" Q9UNE0 2 108894471-108989372 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 3.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Macrophages: 1.1;Squamous epithelial cells: 5.0" "Cancer enhanced" "Detected in many" "colorectal cancer: 4.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "naive CD4 T-cell: 7.5;naive CD8 T-cell: 3.7" "Lineage enriched" "Detected in single" 75 "T-cells: 7.5" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.7;HaCaT: 10.2;OE19: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042292 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "HPA042292: AB_10794648" "unprognostic (1.07e-3)" "unprognostic (1.61e-1)" "unprognostic (2.22e-2)" "unprognostic (1.24e-2)" "unprognostic (4.68e-2)" "unprognostic (1.21e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-2)" "unprognostic (3.70e-1)" "unprognostic (1.31e-1)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (8.83e-7)" "unprognostic (9.21e-2)" "unprognostic (5.61e-2)" "unprognostic (2.29e-1)" "unprognostic (5.03e-3)" 0.0 0.0 0.0 0.9 0.0 0.3 0.2 0.0 0.2 0.6 0.0 1.3 1.1 0.5 0.2 3.6 0.2 0.9 0.0 0.1 0.0 0.6 0.9 0.2 1.6 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.7 1.9 0.0 0.6 0.1 0.0 1.4 1.0 0.0 0.0 0.2 0.9 0.1 0.1 1.2 0.0 0.0 1.2 1.5 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 4.7 0.0 0.4 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 7.5 3.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.4 0.0 0.1 0.6 0.5 0.0 0.8 0.0 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.8 0.0 0.3 0.8 SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 47.0;Excitatory neurons: 108.3;Inhibitory neurons: 160.9;Microglial cells: 164.9;Oligodendrocyte precursor cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 19.8;RPMI-8226: 20.5;TIME: 23.2;U-266/84: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 47: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA044822: AB_2679103, HPA048444: AB_2680396" "unprognostic (1.97e-1)" "unprognostic (8.84e-3)" "unprognostic (8.04e-2)" "unprognostic (1.91e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-1)" "unprognostic (8.00e-2)" "unprognostic (1.76e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (4.57e-2)" "unprognostic (1.95e-1)" "unprognostic (3.54e-2)" "unprognostic (4.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-2)" 6.1 6.7 4.7 3.0 6.1 0.8 4.3 1.3 6.5 5.5 1.6 5.6 1.1 3.7 0.7 2.8 4.8 4.4 6.0 6.3 3.2 6.8 1.1 7.2 2.1 3.0 4.5 3.2 2.0 0.5 1.9 5.2 2.8 4.7 1.4 0.6 1.6 4.4 5.7 3.1 3.3 3.8 3.1 2.1 2.9 4.2 3.9 3.2 2.5 7.3 1.2 5.5 4.2 3.5 0.0 0.1 0.1 2.2 9.0 6.9 0.0 4.2 12.2 3.1 1.1 1.1 0.0 0.0 3.1 3.1 0.7 0.0 0.2 1.8 1.3 0.0 4.2 0.0 0.2 0.0 19.8 0.1 0.0 12.0 2.9 14.1 6.3 1.8 11.4 2.2 0.0 11.7 7.3 0.0 0.0 6.5 1.1 0.0 12.0 2.6 0.0 20.5 0.0 0.0 0.7 2.5 0.0 0.0 0.4 0.1 0.2 0.0 23.2 4.0 12.0 11.5 5.5 4.0 28.6 0.0 0.0 6.3 5.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.7 6.1 1.3 6.5 6.3 3.2 3.0 4.5 2.8 3.1 3.9 3.5 5.3 0.0 0.0 47.0 0.2 1.9 0.4 0.2 1.8 0.5 0.6 0.5 10.7 0.0 0.7 0.0 0.0 0.0 1.5 0.1 0.0 1.1 2.6 9.4 9.6 6.7 1.8 0.0 108.3 0.2 0.2 4.8 0.0 1.1 0.0 0.2 7.5 0.0 4.7 10.1 160.9 0.8 0.0 2.5 1.5 5.2 2.1 1.2 5.4 164.9 0.0 1.7 0.0 42.3 1.9 0.1 0.0 3.0 1.6 0.2 0.0 0.6 2.1 0.0 13.1 3.2 6.8 0.7 9.6 0.8 0.9 0.1 0.5 2.3 0.1 0.0 SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 56.4;Cardiomyocytes: 21.8;Cytotrophoblasts: 15.1;Extravillous trophoblasts: 59.4;Fibroblasts: 15.5;Hofbauer cells: 19.6;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047860, HPA056304, HPA060310" Enhanced Supported "Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "HPA047860: AB_2680187, HPA056304: AB_2683094, HPA060310: AB_2684249" "unprognostic (1.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.94e-2)" "unprognostic (3.18e-2)" "unprognostic (6.34e-2)" "unprognostic (3.41e-2)" "unprognostic (2.02e-3)" "unprognostic (1.80e-2)" "unprognostic (9.67e-2)" "unprognostic (8.61e-2)" "unprognostic (1.78e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-2)" "unprognostic (3.05e-3)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (9.12e-2)" 57.0 24.2 16.1 22.6 29.5 0.7 52.9 29.8 20.3 41.5 58.7 52.0 22.3 44.5 21.7 88.4 33.4 41.8 41.7 15.1 24.2 43.4 66.5 60.4 18.4 46.8 29.5 46.7 20.3 26.9 9.5 50.4 41.6 40.6 39.8 13.6 34.7 42.2 28.5 73.4 24.3 58.0 31.9 36.3 30.5 76.9 26.1 19.9 43.3 39.0 22.8 55.1 43.2 44.5 104.7 27.7 99.6 64.1 78.1 145.8 61.1 166.5 290.6 114.8 133.3 52.2 59.0 0.0 82.2 130.4 72.2 47.7 42.8 105.2 151.6 199.4 31.2 0.2 38.5 75.3 58.7 0.2 13.4 91.5 46.9 103.5 135.1 123.9 154.3 0.0 2.7 0.4 141.5 9.9 0.1 10.3 74.4 61.3 53.7 0.1 80.9 17.4 95.7 136.8 29.6 61.8 97.8 2.1 77.0 115.2 26.5 1.2 158.5 120.1 85.1 46.9 69.6 61.4 36.0 0.9 106.7 2.3 148.1 0.0 2.4 0.0 0.1 1.6 0.1 0.8 1.5 0.4 0.6 0.3 0.7 0.2 0.1 0.0 1.0 0.0 3.5 0.8 16.1 29.5 29.8 20.3 15.1 24.2 46.8 29.5 41.6 31.9 26.1 44.5 56.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 0.0 0.0 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 59.4 15.5 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 7.5 0.1 0.0 0.0 0.0 SOWAHC "ANKRD57, C2orf26, FLJ21870" ENSG00000198142 "Sosondowah ankyrin repeat domain family member C" Q53LP3 2 109614364-109618990 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 147.6;Granulosa cells: 151.0;Squamous epithelial cells: 137.1;Suprabasal keratinocytes: 199.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 160.4;hTCEpi: 50.8;RT4: 66.2" "Low region specificity" "Detected in all" HPA056131 Enhanced Approved Cytosol No No "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "HPA056131: AB_2683047" "unprognostic (6.76e-2)" "unprognostic (6.96e-2)" "unprognostic (9.61e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.87e-1)" "unprognostic (8.91e-3)" "unprognostic (1.63e-2)" "unprognostic (1.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (5.11e-3)" "prognostic favorable (3.56e-5)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (3.50e-1)" "unprognostic (2.54e-2)" 6.3 3.6 2.5 3.5 3.2 0.6 9.4 3.0 2.7 8.0 7.6 11.3 5.1 5.1 3.9 33.3 4.5 8.4 2.0 2.7 4.3 14.0 29.3 7.0 2.9 4.8 6.2 13.0 3.6 5.2 1.9 4.2 4.1 7.0 8.7 5.5 8.3 7.3 1.1 19.3 7.3 6.2 4.0 3.3 5.9 6.5 4.2 4.3 7.9 2.1 7.5 23.1 12.0 4.5 19.3 3.6 10.8 5.9 5.3 8.8 35.1 41.3 24.1 7.1 7.4 17.0 6.0 0.0 16.6 6.3 13.4 18.1 2.5 27.1 7.7 160.4 18.0 0.0 8.6 24.3 4.9 0.0 4.8 4.7 50.8 15.3 10.9 5.9 1.8 0.0 0.3 0.1 5.5 6.4 0.0 1.7 7.6 17.5 16.2 0.0 2.4 0.3 10.7 66.2 13.5 5.8 14.2 2.5 11.3 10.5 5.3 0.4 2.7 5.6 21.6 3.3 3.0 5.3 5.5 0.1 6.6 0.6 13.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 3.2 3.0 2.7 2.7 4.3 4.8 6.2 4.1 4.0 4.2 4.5 18.9 16.0 9.8 2.9 1.2 147.6 43.2 32.0 93.9 15.7 30.5 22.7 3.6 20.0 14.7 12.9 10.4 4.3 0.7 61.1 3.9 15.9 37.8 28.7 21.1 10.8 15.6 2.7 0.2 7.1 28.6 15.6 13.3 76.9 0.0 151.0 6.8 53.2 8.0 0.0 1.2 32.7 10.2 7.0 15.1 13.7 11.8 6.2 19.6 0.0 3.4 7.3 2.1 1.5 2.4 14.2 34.2 15.1 0.6 21.0 21.5 25.1 5.5 20.7 13.1 12.1 20.8 20.8 13.2 137.1 199.3 10.0 2.2 5.3 36.7 80.9 RGPD5 "BS-63, DKFZp686I1842, RGP5" ENSG00000015568 "RANBP2 like and GRIP domain containing 5" Q99666 2 109792758-109857705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.50e-2)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.23e-1)" "unprognostic (4.23e-2)" "unprognostic (3.19e-1)" "unprognostic (3.19e-3)" "unprognostic (3.19e-1)" 10.2 8.3 12.0 5.8 16.4 13.8 10.3 5.9 21.9 8.1 8.1 8.2 7.4 10.4 17.5 5.4 7.6 7.2 8.9 16.5 14.7 7.3 6.8 10.3 6.0 3.5 3.4 13.0 13.5 14.7 8.2 11.1 4.3 12.3 7.2 22.3 7.0 9.6 6.5 11.6 7.4 7.4 2.7 6.4 7.0 41.2 12.6 3.8 14.4 9.7 5.3 7.5 3.9 14.0 24.3 7.8 26.0 19.5 7.7 8.0 1.2 19.3 16.1 13.8 11.2 20.9 7.8 0.6 12.4 11.7 14.6 8.0 14.3 7.0 17.3 3.7 6.4 18.5 4.1 10.2 8.8 1.5 3.1 8.5 9.5 13.3 14.2 14.5 9.4 7.6 8.8 5.4 10.7 4.5 4.0 0.6 12.7 3.0 9.9 4.3 14.4 0.1 10.4 13.7 31.9 4.5 10.0 1.5 14.0 16.5 0.5 5.4 15.6 14.3 21.1 1.0 14.1 12.2 0.5 0.6 11.7 0.2 4.6 5.4 2.0 2.5 1.9 1.0 3.6 1.7 1.5 2.1 1.4 4.2 2.0 2.1 5.5 2.0 1.2 2.5 1.9 0.6 12.0 16.4 5.9 21.9 16.5 14.7 3.5 3.4 4.3 2.7 12.6 14.0 12.9 3.2 11.8 0.0 9.0 3.4 5.0 0.8 2.8 17.7 2.5 1.4 13.8 0.0 3.7 12.9 16.7 2.4 15.9 1.7 0.0 1.7 4.1 12.3 12.0 7.4 5.3 0.0 7.3 1.0 1.8 7.4 5.1 18.6 0.0 9.4 4.2 0.9 1.8 3.3 4.5 1.4 0.0 2.9 6.5 1.7 2.5 6.6 1.8 1.0 0.9 3.8 0.0 0.0 0.2 1.5 1.7 1.2 10.7 5.5 1.7 0.4 2.6 20.3 0.0 9.7 7.8 4.1 2.9 1.2 3.3 4.4 12.4 1.6 1.0 7.3 LIMS3 ENSG00000256977 "LIM zinc finger domain containing 3" P0CW19 2 109898428-109924868 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 6.5;fallopian tube: 6.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.6;Distal tubular cells: 1.9;Exocrine glandular cells: 1.2;NK-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 12.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 14.1;HMC-1: 41.3" HPA058455 Uncertain Approved "Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723" "unprognostic (2.23e-2)" 1.2 1.7 0.2 2.6 0.2 0.4 0.7 0.2 0.4 1.3 0.2 0.5 0.7 6.5 1.7 1.6 6.4 1.3 1.9 0.2 0.3 2.8 0.2 0.5 0.6 0.4 0.3 2.3 0.9 0.5 0.6 1.5 0.4 0.5 1.2 0.4 1.0 1.0 5.7 0.2 0.8 1.5 0.2 0.5 0.7 1.2 0.3 1.0 0.6 2.0 0.4 1.7 0.3 0.5 0.1 0.1 1.8 2.1 0.7 0.6 0.0 2.2 0.0 0.4 0.9 2.2 0.0 0.0 6.5 0.4 4.2 1.2 0.0 2.6 1.8 3.5 0.0 14.1 0.6 1.3 1.9 2.5 41.3 3.0 1.5 1.6 1.9 0.0 3.5 0.0 3.0 2.3 4.6 0.1 0.0 0.3 2.2 1.4 0.8 2.6 4.4 1.5 1.2 2.2 0.6 5.0 5.7 0.0 1.2 0.1 0.0 0.7 10.4 8.8 8.1 4.6 0.4 0.0 0.0 2.8 1.2 0.0 2.6 5.6 3.2 12.3 0.7 5.4 1.4 0.6 4.7 1.5 2.4 0.2 0.8 0.3 0.6 1.2 5.7 0.2 6.1 8.5 0.2 0.2 0.2 0.4 0.2 0.3 0.4 0.3 0.4 0.2 0.3 0.5 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 MALL BENE ENSG00000144063 "Mal, T cell differentiation protein like" Q13021 2 110083870-110116022 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 368.5;intestine: 235.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 857.8;Ductal cells: 299.2;Pancreatic endocrine cells: 354.9;Paneth cells: 374.4;Proximal enterocytes: 742.2;Urothelial cells: 426.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 8.4;neutrophil: 2.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "A-431: 267.4;A549: 269.9;CAPAN-2: 347.7;fHDF/TERT166: 380.9;HaCaT: 276.4;PC-3: 158.3" "Not detected" "Not detected" HPA051410 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA051410: AB_2681474" "unprognostic (5.17e-1)" "unprognostic (4.15e-2)" "unprognostic (2.92e-1)" "unprognostic (3.53e-1)" "unprognostic (1.92e-2)" "unprognostic (1.66e-1)" "unprognostic (2.22e-1)" "unprognostic (4.46e-2)" "unprognostic (6.50e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (2.37e-1)" "unprognostic (7.27e-2)" "unprognostic (2.23e-1)" "unprognostic (2.84e-1)" "unprognostic (2.80e-1)" "unprognostic (6.50e-3)" 17.2 2.9 3.9 17.2 3.7 2.4 13.4 3.6 3.8 58.2 4.7 114.1 235.4 6.3 5.7 368.5 8.4 20.3 18.6 3.6 4.9 7.0 3.1 79.9 6.1 4.1 4.2 2.0 4.4 97.8 2.6 9.3 4.6 18.9 95.1 0.4 40.8 4.2 6.3 43.7 218.8 14.4 4.9 5.0 9.2 9.7 6.9 3.1 28.6 10.8 55.0 98.6 148.1 4.2 267.4 269.9 0.2 0.9 0.1 0.1 0.8 48.5 2.1 0.2 0.2 44.3 347.7 0.6 127.6 380.9 0.1 276.4 0.0 12.6 0.1 0.7 0.2 1.8 7.3 0.1 1.9 0.1 0.6 4.8 13.9 1.2 0.0 0.0 111.9 0.0 0.1 0.4 0.0 10.0 0.0 1.0 0.2 117.8 158.3 0.1 0.1 1.2 30.4 15.3 0.7 0.2 0.2 9.3 0.7 0.4 0.3 1.4 130.9 0.4 0.9 0.7 0.8 0.3 0.4 31.7 0.4 0.4 0.2 8.4 0.4 0.6 0.2 0.2 0.2 0.5 0.5 0.4 0.2 0.5 0.3 0.5 2.5 1.2 0.1 0.4 0.3 0.3 3.9 3.7 3.6 3.8 3.6 4.9 4.1 4.2 4.6 4.9 6.9 4.2 45.1 41.7 185.9 0.3 2.0 16.4 107.2 38.6 3.4 0.0 10.9 6.1 3.2 2.8 64.6 1.8 0.0 0.3 0.4 857.8 0.0 299.2 26.3 3.2 1.8 50.6 17.5 0.0 0.8 66.1 0.1 8.2 2.6 7.6 7.0 0.4 33.9 0.5 8.2 0.0 0.1 51.2 30.5 0.9 3.8 9.7 2.5 2.9 14.2 2.8 1.0 0.1 0.0 0.0 0.0 354.9 374.4 1.2 0.0 187.4 742.2 14.6 19.4 0.1 0.0 1.1 5.6 27.2 1.3 57.9 13.2 0.5 2.4 0.6 97.4 426.0 NPHP1 "JBTS4, NPH1, SLSN1" ENSG00000144061 "Nephrocystin 1" O15259 2 110122311-110205066 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant, Joubert syndrome, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 36.2" "Cell type enhanced" "Detected in many" "Early spermatids: 148.5;Endometrial ciliated cells: 136.3;Respiratory ciliated cells: 167.4;Spermatocytes: 146.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046093, HPA074071" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "HPA046093: AB_2679535, HPA074071: " "unprognostic (2.10e-2)" "unprognostic (1.96e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (4.63e-2)" "unprognostic (1.56e-3)" "unprognostic (4.66e-2)" "unprognostic (1.64e-2)" "unprognostic (1.16e-1)" "unprognostic (1.66e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "unprognostic (2.93e-3)" "unprognostic (3.35e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" 3.1 3.7 4.5 1.0 4.7 0.1 4.0 4.0 8.6 4.7 11.1 5.3 1.0 5.4 9.0 1.3 17.1 3.3 4.8 4.6 5.2 8.0 0.8 4.3 0.9 5.4 5.8 4.5 3.2 17.0 11.7 1.3 5.0 4.4 1.7 10.8 2.5 4.7 36.2 1.7 1.9 4.6 4.6 1.9 3.6 24.9 5.5 1.1 7.4 10.8 0.6 4.1 2.7 4.6 9.8 3.1 5.9 4.3 3.3 7.9 1.3 2.4 7.9 8.5 8.4 3.1 7.1 0.5 6.0 5.8 7.8 4.7 2.8 7.5 10.0 1.7 3.9 0.2 1.9 2.1 4.5 1.4 0.0 5.2 4.4 12.7 3.6 12.0 4.7 1.9 0.1 0.8 4.9 2.0 1.0 2.1 2.8 0.2 4.9 0.2 6.5 0.3 14.5 0.8 3.0 3.1 3.2 4.2 9.2 2.8 5.1 1.0 3.2 4.9 4.2 5.0 7.7 2.4 2.9 0.7 13.9 0.2 3.3 0.3 0.0 0.0 0.3 0.1 0.5 0.8 0.2 0.1 0.3 1.5 0.5 0.3 0.2 1.1 0.0 0.0 0.0 0.1 4.5 4.7 4.0 8.6 4.6 5.2 5.4 5.8 5.0 4.6 5.5 4.6 8.3 6.4 8.9 31.6 1.6 5.2 8.7 18.1 2.8 11.8 5.3 6.6 14.3 8.6 23.3 9.2 47.9 1.9 0.3 0.8 19.6 15.6 148.5 136.3 15.8 7.0 0.0 0.0 29.1 4.9 0.5 8.1 0.0 17.0 0.0 13.4 9.3 2.7 1.4 21.9 15.0 0.9 18.3 0.8 3.1 65.2 7.5 1.4 7.2 4.7 0.0 12.3 0.0 12.1 11.5 6.4 1.3 9.8 0.1 3.1 0.2 35.9 167.4 69.1 13.1 14.3 10.3 146.3 24.9 1.0 4.0 0.3 1.3 9.6 1.7 5.8 MTLN "LEMP, LINC00116, MOXI, MPM, NCRNA00116, SMIM37" ENSG00000175701 Mitoregulin Q8NCU8 2 110211529-110245420 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "heart muscle: 229.3;skeletal muscle: 784.7;tongue: 280.3" "Cell type enhanced" "Detected in some" "Adipocytes: 27.4;Cytotrophoblasts: 43.7;Extravillous trophoblasts: 32.8;Hofbauer cells: 78.4;Syncytiotrophoblasts: 20.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (3.74e-2)" "unprognostic (1.86e-1)" "unprognostic (7.68e-2)" "unprognostic (6.99e-2)" "unprognostic (2.04e-1)" "unprognostic (2.64e-1)" "unprognostic (3.49e-3)" "unprognostic (8.20e-2)" "unprognostic (9.10e-2)" "unprognostic (6.08e-2)" "unprognostic (5.08e-3)" "unprognostic (8.27e-2)" "unprognostic (1.97e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "unprognostic (8.80e-2)" "unprognostic (1.95e-2)" 66.5 68.9 67.3 22.2 71.2 10.1 51.1 80.5 103.8 42.0 63.5 73.9 41.6 58.0 52.1 63.5 41.6 9.2 229.3 68.8 77.2 69.8 78.0 40.2 15.9 75.8 71.4 33.6 46.2 37.0 41.3 12.9 75.6 48.6 12.4 11.0 43.9 34.0 784.7 44.6 46.8 16.7 70.4 44.4 57.3 25.7 78.1 18.5 48.0 280.3 12.0 55.7 46.1 75.6 0.4 125.0 13.3 15.3 14.7 17.5 81.1 49.9 38.6 58.7 39.2 86.0 39.7 16.9 95.0 13.8 81.4 52.9 13.2 57.5 9.6 72.0 51.4 10.1 30.5 73.3 61.2 35.6 50.3 45.6 67.8 48.8 0.0 31.8 52.9 50.2 28.6 40.6 28.1 130.0 49.8 121.6 34.1 39.9 36.9 5.5 28.0 51.9 37.2 77.9 29.5 19.4 27.7 95.2 57.1 8.9 26.4 59.2 41.0 57.7 81.3 56.9 75.9 67.8 48.0 5.3 60.0 56.1 42.1 9.6 101.9 13.8 109.6 112.1 125.1 104.0 123.5 118.7 110.6 115.0 129.1 129.1 5.6 85.9 67.6 150.2 119.0 77.4 67.3 71.2 80.5 103.8 68.8 77.2 75.8 71.4 75.6 70.4 78.1 75.6 27.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 8.7 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 32.8 11.8 0.0 0.0 0.0 0.0 0.0 0.0 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 20.2 1.5 0.0 0.0 0.0 LIMS4 LIMS3L ENSG00000256671 "LIM zinc finger domain containing 4" P0CW20 2 110446640-110473075 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Exocrine glandular cells: 1.5;Glandular and luminal cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.0;hTEC/SVTERT24-B: 1.8;HUVEC TERT2: 1.0;U-138 MG: 1.9" HPA058455 Uncertain Uncertain "Focal adhesion sites,Cytosol" NA NA "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Cytosol "Focal adhesion sites" "HPA058455: AB_2683723" "unprognostic (2.12e-1)" 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.3 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 RGPD6 RGP6 ENSG00000183054 "RANBP2 like and GRIP domain containing 6" Q99666 2 110513802-110577222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 9.6;Alveolar cells type 2: 17.1;Club cells: 8.1;Excitatory neurons: 10.7;Inhibitory neurons: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.5;SCLC-21H: 10.5" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.11e-2)" "unprognostic (6.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.67e-2)" "unprognostic (1.53e-1)" "unprognostic (3.22e-1)" "unprognostic (2.91e-2)" "unprognostic (4.14e-4)" "unprognostic (2.04e-1)" 12.9 8.4 5.0 0.7 2.3 6.3 13.3 6.3 6.4 13.3 6.4 11.5 1.5 9.7 0.9 7.4 12.2 0.0 12.9 2.3 4.9 9.5 14.0 14.4 2.3 4.5 1.5 15.2 18.1 2.0 22.9 1.8 2.8 14.8 0.6 1.9 9.7 0.1 14.7 17.2 12.0 1.0 3.9 9.6 11.8 31.9 2.5 0.7 14.2 2.1 0.7 10.8 10.7 7.6 7.0 2.6 1.2 2.0 0.0 0.5 2.9 1.3 0.0 0.8 0.1 5.7 1.5 0.4 4.2 2.5 3.4 5.2 0.2 2.4 0.0 1.6 11.5 6.8 0.9 1.0 0.1 2.2 0.3 0.4 1.5 1.3 3.1 1.0 0.0 2.1 2.7 2.0 0.0 3.7 1.8 0.0 7.6 1.4 6.7 2.6 4.1 0.0 2.6 0.7 10.5 4.8 1.1 0.2 3.1 4.1 0.1 0.4 1.5 1.4 4.0 0.4 6.0 3.8 0.4 0.5 2.6 0.0 2.5 4.7 1.5 2.0 1.6 0.8 2.4 2.0 2.3 1.7 1.0 3.1 2.3 1.4 4.7 1.5 1.8 2.2 0.5 0.3 5.0 2.3 6.3 6.4 2.3 4.9 4.5 1.5 2.8 3.9 2.5 7.6 0.1 9.6 17.1 0.0 0.3 0.9 0.2 0.0 0.0 0.0 0.1 0.1 1.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 7.0 0.0 0.0 0.0 0.3 0.3 0.0 0.5 1.8 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.3 BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.9;lymphoid tissue: 27.5;testis: 30.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.8;Granulosa cells: 66.1;Plasma cells: 35.2;Spermatocytes: 85.6;Spermatogonia: 20.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 221.5" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Cytosol "HPA006123: AB_1845498" "unprognostic (7.74e-2)" "unprognostic (3.45e-2)" "unprognostic (9.72e-3)" "prognostic unfavorable (3.65e-4)" "unprognostic (1.61e-1)" "unprognostic (5.62e-3)" "prognostic unfavorable (1.03e-5)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.26e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.37e-5)" "unprognostic (1.76e-1)" "unprognostic (0.00e+0)" "unprognostic (2.45e-2)" "unprognostic (3.64e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" 0.5 0.4 0.1 8.4 0.3 11.9 1.2 0.1 0.1 0.9 0.0 4.3 4.0 1.0 3.5 4.7 0.5 0.9 0.6 0.1 0.1 0.3 0.6 1.2 15.9 0.1 0.6 0.4 0.2 0.7 0.0 3.2 0.3 0.3 5.7 0.1 0.9 0.1 0.1 2.7 3.5 2.2 0.0 5.6 1.9 30.3 0.4 27.5 0.4 0.2 17.0 2.4 1.6 0.3 96.0 29.4 68.5 46.8 3.8 5.3 38.8 50.9 32.9 85.6 62.3 58.3 55.0 64.7 30.9 30.1 80.1 43.2 93.9 35.0 105.7 51.4 45.6 221.5 26.2 50.6 0.8 63.5 57.0 1.7 2.8 65.2 33.1 12.7 49.8 73.2 96.8 126.5 76.8 33.7 126.3 39.0 71.2 39.4 55.3 69.3 64.2 102.7 18.3 27.0 48.3 21.4 34.2 31.4 27.2 44.1 24.0 60.6 19.1 39.7 57.5 28.8 69.0 67.3 65.5 75.4 24.2 48.6 69.8 1.1 0.0 0.2 0.2 0.0 0.3 0.5 0.9 0.5 0.1 0.5 0.6 0.4 0.0 0.5 0.0 0.9 1.5 0.3 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.6 0.3 0.0 0.4 0.3 0.2 0.0 1.5 0.0 5.5 0.5 0.5 2.0 0.6 0.0 0.9 0.8 1.1 0.0 1.6 0.0 0.0 5.8 2.5 2.4 0.0 0.3 13.5 4.5 1.5 1.1 0.0 24.8 0.2 0.0 9.8 2.2 2.0 2.2 0.0 66.1 1.8 0.3 8.1 0.0 0.2 3.1 4.1 1.6 1.4 7.5 0.3 2.0 0.0 0.0 0.6 0.0 0.0 0.5 1.0 0.1 0.0 0.4 35.2 0.5 0.3 0.1 1.8 0.0 6.6 0.2 3.7 85.6 20.0 4.0 0.4 0.7 2.9 0.5 5.9 0.9 ACOXL FLJ11042 ENSG00000153093 "Acyl-CoA oxidase like" Q9NUZ1 2 110732539-111120610 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 7.2;lung: 9.3" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 41.9" "Group enriched" "Detected in some" 6 "lung cancer: 0.6;prostate cancer: 1.1;testis cancer: 2.1;urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 12.1;RPMI-8226: 22.0;RT4: 29.3;U-266/70: 18.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA035392, HPA035393" Supported Nucleoli,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Cytosol Nucleoli "HPA035392: AB_2674604, HPA035393: AB_2674605" "unprognostic (1.62e-1)" "unprognostic (7.30e-2)" "unprognostic (6.77e-4)" "unprognostic (2.93e-7)" "unprognostic (1.32e-2)" "unprognostic (7.84e-5)" "unprognostic (1.28e-1)" "unprognostic (1.53e-2)" "unprognostic (1.29e-1)" "unprognostic (7.31e-2)" "unprognostic (7.24e-2)" "unprognostic (3.24e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (2.73e-1)" "unprognostic (1.72e-1)" "prognostic favorable (6.48e-4)" 1.1 0.6 0.4 0.5 0.7 1.5 0.1 0.2 0.4 0.4 0.0 0.5 0.5 0.5 7.2 0.4 0.3 0.6 1.2 0.3 0.1 0.5 0.3 9.3 0.9 0.4 0.4 0.2 1.0 2.9 0.3 0.7 0.3 3.2 0.3 0.7 0.6 0.0 1.3 0.7 0.6 0.1 0.0 0.6 0.5 3.2 0.2 0.3 0.8 0.0 1.2 4.6 0.1 0.5 12.1 0.2 0.3 0.2 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.9 0.7 0.3 0.5 0.1 0.3 1.3 0.0 0.1 0.0 0.3 3.5 0.2 0.5 0.5 0.0 0.0 0.3 0.1 1.2 0.0 0.1 0.3 0.0 0.6 1.8 1.8 0.1 4.4 0.9 0.4 4.2 0.0 0.3 0.6 0.2 22.0 0.0 29.3 2.5 1.0 0.3 0.5 0.1 0.6 0.4 1.2 0.3 0.2 1.0 0.2 0.1 18.7 4.8 0.7 0.0 0.1 0.1 0.7 0.3 0.3 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.9 0.2 0.2 0.2 0.1 0.1 0.4 0.7 0.2 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.2 0.5 0.3 0.0 41.9 0.0 1.0 0.3 0.3 0.0 0.0 0.6 0.1 0.3 0.5 0.0 0.7 0.0 0.0 0.0 0.1 1.3 0.0 0.2 5.4 0.2 0.1 0.2 1.2 0.0 2.2 0.0 0.0 0.4 0.0 0.8 0.0 5.9 0.0 0.0 0.1 0.0 2.0 0.3 0.0 0.0 0.8 8.1 0.0 0.2 0.0 0.0 0.0 0.1 1.0 1.0 1.3 0.1 2.3 0.0 7.5 0.8 0.0 0.1 0.1 0.3 0.0 0.2 0.3 1.6 2.7 0.0 0.3 0.0 1.1 0.0 0.2 0.8 BCL2L11 "BIM, BimEL, BimL, BimS, BOD" ENSG00000153094 "BCL2 like 11" O43521 2 111119378-111168445 "Predicted intracellular proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 118.3;Plasma cells: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/70: 91.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026332, CAB079899" Approved Supported Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Mitochondria "CAB026332: AB_566386, CAB079899: AB_10981505" "unprognostic (1.43e-1)" "unprognostic (9.46e-3)" "unprognostic (1.88e-1)" "unprognostic (1.50e-2)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "unprognostic (1.05e-1)" "unprognostic (5.63e-2)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (2.55e-2)" "unprognostic (9.71e-3)" "unprognostic (8.15e-3)" "unprognostic (7.86e-2)" 8.1 7.4 4.2 16.4 5.0 38.8 12.5 3.7 3.7 7.2 4.6 11.0 7.2 6.5 4.9 9.8 7.0 8.8 5.7 3.0 3.9 10.7 14.3 8.5 24.2 4.3 4.0 10.3 10.3 18.8 9.4 6.0 4.5 7.8 11.9 12.1 10.1 7.1 12.3 5.8 11.7 4.8 3.9 16.3 7.0 8.1 4.4 18.9 16.6 7.3 23.0 8.9 8.2 6.7 8.0 2.4 10.8 10.4 9.1 4.7 29.1 1.2 2.3 3.3 3.3 6.6 24.9 32.0 6.5 1.2 18.9 9.5 10.0 3.9 2.0 24.9 18.2 39.7 8.1 10.5 3.9 14.6 8.8 4.8 10.5 3.7 3.8 7.0 4.6 14.2 20.8 46.6 0.7 5.2 15.3 14.7 13.2 6.3 7.5 19.5 10.3 40.7 4.5 13.0 9.3 24.0 11.0 14.5 8.3 7.1 5.0 31.2 1.9 1.7 11.4 3.7 4.3 91.2 19.5 45.3 2.7 10.1 1.5 5.2 3.7 1.8 1.7 2.6 1.8 3.3 2.3 1.9 1.9 1.9 1.5 1.5 5.2 1.7 5.7 0.4 5.9 1.5 4.2 5.0 3.7 3.7 3.0 3.9 4.3 4.0 4.5 3.9 4.4 6.7 33.9 3.2 9.9 2.9 61.3 17.5 18.2 7.0 34.7 7.4 19.5 29.2 19.3 12.8 10.3 9.2 10.4 4.6 43.9 37.6 13.7 9.7 118.3 36.6 10.8 18.0 21.5 26.5 2.2 6.5 7.8 11.6 8.6 54.7 11.4 5.9 14.6 11.3 10.9 0.0 4.8 15.2 12.2 26.8 52.6 39.2 5.9 34.8 23.2 6.5 41.0 12.1 5.2 3.0 5.3 8.8 16.4 3.8 137.9 15.9 16.6 6.4 15.2 21.1 0.0 11.8 11.9 7.3 17.7 66.1 10.9 5.7 41.0 2.5 12.3 16.0 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Kupffer cells: 119.8;Macrophages: 46.5;Microglial cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 8.6;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;Hep G2: 39.9;HUVEC TERT2: 38.4;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 59.8 22.8 13.5 28.0 1.5 15.3 18.0 29.3 12.6 44.7 10.9 12.3 11.5 26.3 8.4 15.5 12.0 7.0 22.0 22.5 11.4 21.0 13.6 13.1 23.5 22.3 12.6 9.9 21.2 15.5 20.1 22.4 14.1 7.9 16.6 6.4 16.3 3.2 6.4 14.3 14.4 18.4 30.6 13.9 17.2 30.1 6.8 10.1 4.6 8.9 13.6 9.4 22.0 1.0 1.7 7.6 17.3 0.4 0.2 12.3 0.0 0.2 1.0 1.7 35.1 2.2 0.1 8.1 0.1 7.9 0.2 10.2 0.0 1.4 1.5 5.5 7.0 0.0 39.9 0.3 0.2 1.5 0.5 0.0 8.9 0.6 4.0 38.4 1.5 2.2 3.5 2.9 1.8 0.0 9.1 4.8 1.1 6.0 2.9 2.1 3.0 19.4 23.4 0.3 7.2 0.2 0.5 3.2 2.7 0.0 0.4 5.8 1.0 3.4 0.1 0.0 3.1 4.8 0.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.5 0.1 0.0 0.2 22.8 28.0 18.0 29.3 22.0 22.5 23.5 22.3 22.4 18.4 30.1 22.0 8.8 3.2 27.7 162.6 1.7 1.7 2.9 0.3 1.8 0.6 2.1 4.3 2.7 2.8 6.4 0.0 2.1 3.3 0.4 1.2 1.9 1.1 2.3 8.0 4.7 10.2 0.0 0.4 5.0 1.0 1.1 3.2 0.5 12.1 0.0 3.8 28.5 9.2 25.5 0.0 7.0 2.0 0.0 119.8 1.8 2.7 5.0 46.5 0.0 124.6 1.5 7.7 0.0 10.6 0.6 1.2 1.9 6.8 10.8 2.9 4.4 1.9 1.5 11.3 6.6 1.5 9.2 0.6 1.5 0.6 1.3 18.9 1.3 3.5 1.9 1.6 TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" 10.5 12.2 6.8 14.7 6.6 7.9 20.1 6.1 8.0 12.9 6.9 28.4 28.6 11.0 18.5 10.5 8.4 12.1 5.0 5.9 7.1 7.9 7.4 11.7 15.4 7.5 10.0 6.0 11.3 12.9 9.2 15.1 8.0 30.7 27.8 6.9 15.4 15.9 3.1 13.7 30.5 13.4 7.1 15.5 22.8 5.0 8.3 9.7 15.0 4.2 14.6 17.1 9.0 6.9 21.7 6.4 5.9 25.8 24.9 32.6 21.4 35.5 46.8 21.9 26.7 16.6 28.6 20.9 18.2 47.3 30.2 34.9 3.8 21.6 28.7 12.8 4.1 27.5 4.6 15.2 24.7 19.6 28.9 22.3 25.9 28.0 22.0 21.4 23.6 9.6 16.9 13.1 31.8 13.7 9.3 10.8 4.8 35.0 16.4 7.6 8.9 17.0 20.3 30.2 4.6 6.4 15.4 38.6 34.6 15.5 20.4 14.7 26.6 22.3 6.8 17.6 7.8 10.6 18.1 12.9 25.9 10.1 16.3 5.4 3.0 2.6 3.2 5.2 5.6 5.9 6.9 4.4 2.7 4.9 6.2 3.6 1.8 3.5 6.7 2.7 7.4 3.6 6.8 6.6 6.1 8.0 5.9 7.1 7.5 10.0 8.0 7.1 8.3 6.9 18.3 28.9 13.9 18.9 23.3 12.2 14.5 20.9 39.9 5.0 32.9 14.4 4.6 20.0 21.6 18.4 2.1 15.9 12.3 59.5 0.0 42.9 18.7 14.4 26.5 19.9 17.4 6.3 18.4 89.3 25.5 17.5 46.4 24.9 13.3 14.5 35.7 10.1 21.7 6.7 16.4 53.6 12.2 37.7 10.9 24.5 9.9 22.7 3.6 30.0 20.9 4.0 6.2 21.6 23.1 69.7 47.1 3.0 21.6 28.9 44.9 4.7 17.9 7.9 0.0 5.4 17.2 4.9 5.6 29.9 12.8 29.1 20.5 11.8 38.2 23.9 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 ZC3H8 "Fliz1, ZC3HDC8" ENSG00000144161 "Zinc finger CCCH-type containing 8" Q8N5P1 2 112211529-112255136 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034803, HPA034804" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies" "HPA034803: AB_2674338, HPA034804: AB_10670284" "unprognostic (2.45e-1)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.12e-6)" "unprognostic (4.93e-2)" "unprognostic (1.01e-1)" "unprognostic (4.29e-3)" "unprognostic (8.76e-2)" "unprognostic (1.20e-2)" "unprognostic (5.04e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (2.74e-2)" "unprognostic (3.49e-2)" "unprognostic (8.02e-3)" "unprognostic (4.88e-3)" 3.6 3.9 4.7 5.7 4.8 6.2 8.0 6.5 6.2 5.4 3.1 4.6 5.2 4.6 4.4 8.6 5.1 2.6 8.6 5.0 4.7 5.7 5.9 2.9 8.5 4.5 4.1 6.0 9.0 11.2 6.6 3.7 4.5 5.6 6.0 5.9 7.1 3.9 11.0 7.6 4.6 4.4 4.0 6.1 4.4 9.0 4.1 9.1 7.2 11.0 8.6 4.9 6.1 4.8 22.1 10.5 13.2 13.7 7.4 8.0 20.6 6.8 5.8 9.5 7.9 25.3 8.3 45.6 12.4 4.8 13.3 13.1 19.4 13.7 12.5 16.2 9.0 30.3 11.8 12.9 11.7 28.6 13.4 10.0 27.0 18.4 28.4 7.0 7.2 27.3 39.2 12.2 7.5 14.6 31.0 25.7 12.2 23.1 29.2 21.2 22.5 18.8 8.7 9.7 19.8 15.4 12.9 13.7 29.9 11.5 10.9 15.1 9.6 12.3 15.9 8.8 17.4 21.9 27.9 44.4 8.8 23.4 4.9 2.7 2.5 0.8 4.0 2.0 8.4 5.9 4.2 4.3 2.5 6.1 7.1 5.9 1.4 7.2 2.6 4.1 4.7 2.4 4.7 4.8 6.5 6.2 5.0 4.7 4.5 4.1 4.5 4.0 4.1 4.8 15.5 9.6 15.2 17.0 35.6 12.6 18.2 16.6 30.7 50.2 28.7 28.6 35.4 12.8 22.8 7.3 41.7 18.1 38.7 13.4 27.4 15.2 30.9 25.5 28.0 15.4 14.9 19.8 35.8 18.6 16.8 16.4 12.2 15.1 35.4 20.2 13.6 11.3 11.4 38.7 46.2 27.4 22.4 15.7 7.8 40.6 22.1 13.7 1.8 12.2 18.1 16.1 43.3 41.2 27.8 19.5 11.3 20.3 14.3 21.2 12.7 24.3 17.4 53.5 13.1 20.9 16.2 60.9 39.0 34.3 17.8 14.2 31.6 24.4 24.0 12.5 ZC3H6 "FLJ41410, FLJ45877, KIAA2035, ZC3HDC6" ENSG00000188177 "Zinc finger CCCH-type containing 6" P61129 2 112275597-112340063 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036019, HPA036020, HPA076065" Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus" "HPA036019: AB_10673228, HPA036020: AB_2674904, HPA076065: AB_2732300" "unprognostic (1.05e-2)" "unprognostic (3.01e-1)" "unprognostic (2.77e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-3)" "unprognostic (1.83e-1)" "unprognostic (3.99e-3)" "unprognostic (3.30e-1)" "unprognostic (1.37e-1)" "unprognostic (2.43e-2)" "unprognostic (1.68e-1)" "unprognostic (4.41e-2)" "unprognostic (6.42e-3)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (6.45e-2)" 3.9 2.5 3.1 1.8 4.4 1.7 3.3 5.5 4.1 3.2 0.0 3.0 1.4 2.9 3.4 1.8 3.6 1.8 2.9 2.6 3.1 2.1 1.8 2.4 2.9 3.1 3.3 6.1 2.3 3.0 3.4 1.7 3.0 2.4 1.7 9.4 2.8 2.1 5.8 4.4 2.6 1.8 2.9 3.1 2.2 2.9 3.0 3.8 3.7 5.7 2.6 2.9 2.9 5.4 1.1 0.4 2.3 2.2 2.1 4.1 0.7 1.2 1.9 0.7 1.5 0.2 1.4 1.7 0.9 0.7 2.0 0.6 0.7 0.3 1.0 2.0 0.2 0.3 0.5 0.0 1.9 0.4 0.4 1.6 3.3 0.8 5.5 3.4 1.2 2.2 0.4 3.0 1.7 1.0 1.0 0.6 1.5 0.7 0.5 0.6 0.1 1.6 1.0 0.2 1.7 2.3 1.1 0.6 1.2 1.2 0.7 0.6 1.8 1.1 0.1 1.3 0.5 3.1 0.9 1.5 2.2 1.1 3.0 0.5 0.6 0.8 0.9 0.4 1.0 1.3 1.3 1.0 0.6 1.7 1.4 1.2 1.2 0.6 1.3 1.0 1.2 0.4 3.1 4.4 5.5 4.1 2.6 3.1 3.1 3.3 3.0 2.9 3.0 5.4 33.3 38.5 32.0 33.3 24.4 17.3 30.0 12.1 33.0 69.3 31.9 33.4 68.7 20.0 20.6 22.0 54.2 21.1 17.5 7.8 29.4 13.1 16.8 39.3 16.0 27.7 16.2 14.5 46.7 14.8 7.3 31.7 7.7 16.2 26.6 41.2 25.7 16.7 12.4 114.4 62.2 13.5 6.1 19.5 14.2 12.4 46.3 16.2 5.4 29.0 21.1 47.6 30.9 43.7 114.4 16.0 10.4 36.1 12.2 30.7 12.1 22.3 30.6 89.5 32.9 50.8 31.0 75.2 46.4 13.7 18.5 7.9 28.6 26.9 12.9 20.6 RGPD8 "RanBP2alpha, RANBP2L1" ENSG00000169629 "RANBP2 like and GRIP domain containing 8" O14715 2 112368369-112434488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 15.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Early spermatids: 24.3;Excitatory neurons: 9.8;Late spermatids: 10.1;Microglial cells: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 16.2;hTEC/SVTERT24-B: 13.4" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (3.62e-1)" "unprognostic (7.61e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-3)" "unprognostic (3.17e-3)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" "unprognostic (2.57e-1)" "unprognostic (9.18e-3)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" 4.3 1.8 2.7 2.8 3.6 10.6 4.5 8.6 7.6 2.8 4.5 2.1 1.6 3.1 5.4 1.4 2.2 2.9 1.8 3.7 3.5 2.4 5.1 3.3 2.4 2.2 2.4 3.2 3.0 2.2 2.6 3.3 1.9 2.6 2.3 7.9 2.5 2.9 1.7 3.8 2.1 2.6 1.1 3.0 1.7 15.6 2.6 3.2 2.4 2.2 3.0 2.6 1.6 5.5 6.1 2.6 4.3 2.6 1.6 3.6 0.1 2.4 1.9 2.3 1.5 5.3 0.4 0.0 1.7 4.0 2.0 2.9 12.3 1.7 2.4 8.7 4.0 16.2 4.5 4.1 2.2 0.1 0.2 0.6 2.2 13.4 3.4 5.7 1.9 2.8 8.4 0.4 3.6 2.5 8.7 2.1 3.0 0.9 3.7 0.0 0.5 0.1 1.3 2.5 2.7 0.5 8.1 0.1 1.7 3.0 1.2 6.8 8.9 1.3 1.8 6.9 4.4 0.0 0.0 0.0 0.5 2.9 0.3 1.3 0.4 0.4 1.0 0.3 1.4 0.5 0.7 0.9 0.4 0.6 1.0 0.6 0.3 0.5 0.8 0.7 0.4 0.3 2.7 3.6 8.6 7.6 3.7 3.5 2.2 2.4 1.9 1.1 2.6 5.5 1.0 9.6 3.6 1.6 2.8 0.4 0.4 0.2 5.2 0.8 0.3 0.3 8.0 1.5 1.9 0.0 2.1 0.2 0.7 0.1 0.0 0.5 24.3 0.6 0.5 1.5 0.0 2.5 9.8 1.1 0.1 2.2 2.6 0.6 5.1 0.6 0.7 0.2 0.4 0.0 7.0 0.4 0.0 0.6 0.8 10.1 0.3 2.0 0.0 9.4 2.3 0.4 0.0 7.5 5.2 0.9 0.0 0.0 2.4 0.0 0.0 0.1 6.7 0.7 0.0 0.9 0.9 6.8 2.7 2.7 0.0 0.4 3.1 0.0 0.0 0.3 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482156-112541739 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA066819: AB_2685728" "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 1.0 0.8 2.3 0.9 3.0 1.8 0.6 1.6 3.0 0.6 0.1 0.8 0.6 1.0 0.8 1.1 0.5 1.1 1.6 2.4 1.7 0.8 0.6 1.3 1.0 1.5 1.9 0.6 0.8 0.8 0.3 1.2 1.6 0.6 0.8 1.4 0.4 0.7 3.7 1.4 0.6 1.3 0.8 0.9 0.6 0.6 2.7 1.0 0.9 3.8 0.8 1.0 0.4 3.5 2.9 2.2 2.7 6.2 3.2 4.6 1.1 4.9 4.0 5.1 4.4 2.7 1.0 2.7 2.7 4.2 3.3 2.0 4.8 2.5 6.2 1.9 2.7 2.3 3.1 3.4 1.4 3.2 1.1 2.1 1.7 7.5 4.0 2.3 4.4 1.8 3.8 2.1 4.1 1.5 2.8 1.8 2.4 0.8 4.4 3.0 3.1 1.5 1.6 2.2 5.8 4.0 3.8 1.2 6.7 1.8 1.3 1.8 4.4 6.0 4.4 4.8 3.7 1.1 2.5 2.2 6.7 2.4 2.6 0.6 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.0 2.3 3.0 1.6 3.0 2.4 1.7 1.5 1.9 1.6 0.8 2.7 3.5 14.0 12.8 6.4 19.2 7.0 20.3 4.9 8.3 4.6 15.6 6.4 6.0 39.1 2.8 6.7 12.9 12.5 3.2 10.6 8.0 0.0 7.2 12.2 8.3 28.3 18.5 11.3 16.2 34.1 9.6 2.4 12.6 2.6 10.8 0.0 11.7 15.7 10.4 11.4 8.4 24.0 5.8 16.2 24.2 19.2 5.1 3.1 17.0 7.2 20.6 17.2 9.8 8.2 24.6 72.8 9.4 5.2 5.7 9.1 6.6 2.4 6.0 4.2 20.2 6.6 15.4 12.2 4.5 5.0 6.5 18.0 1.2 7.6 7.7 6.1 4.1 POLR1B "FLJ10816, FLJ21921, RPA135, RPA2, Rpo1-2" ENSG00000125630 "RNA polymerase I subunit B" Q9H9Y6 2 112541915-112579818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Nucleotidyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early spermatids: 181.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037528 Supported "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli fibrillar center" Cytosol "HPA037528: AB_10671627" "unprognostic (1.66e-1)" "unprognostic (3.17e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (2.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.98e-3)" "unprognostic (1.98e-1)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (6.12e-2)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" 5.7 4.6 2.9 5.6 3.0 4.1 8.2 3.5 3.1 5.3 3.8 5.5 4.4 4.7 4.4 8.1 6.7 3.7 4.1 2.8 3.5 8.1 10.7 4.1 9.3 2.6 2.7 6.3 8.1 11.9 4.4 5.6 2.5 5.0 6.2 5.2 3.8 4.7 7.5 5.2 3.8 5.3 2.6 6.7 4.3 8.4 3.1 7.2 10.7 6.4 10.8 7.9 3.6 3.4 21.1 21.6 11.2 28.2 13.9 13.2 24.0 15.1 11.9 24.0 21.5 48.8 12.5 46.1 22.9 9.8 18.8 29.5 56.1 30.6 28.4 22.3 30.9 26.5 21.4 37.1 14.2 43.6 18.1 12.7 21.6 25.4 39.6 9.8 19.9 10.2 55.0 16.8 13.2 17.5 20.5 29.7 66.3 29.5 42.8 30.9 21.3 54.1 17.2 19.2 34.3 29.1 12.1 34.7 19.7 13.8 16.3 15.6 15.9 14.6 23.2 13.7 21.8 24.3 44.4 40.9 11.0 28.8 13.1 0.4 8.0 3.3 10.0 8.3 21.5 11.4 9.9 10.7 14.2 11.6 12.4 12.5 0.8 15.3 6.5 3.5 15.2 9.6 2.9 3.0 3.5 3.1 2.8 3.5 2.6 2.7 2.5 2.6 3.1 3.4 4.8 16.0 5.9 4.6 8.5 15.0 4.7 4.1 9.6 3.6 4.2 3.7 6.4 7.2 5.8 9.2 2.1 3.4 6.5 2.0 5.9 3.9 181.9 3.5 7.6 5.8 3.6 5.9 8.8 4.6 2.8 3.5 8.6 4.2 5.1 6.5 1.4 9.4 3.8 1.7 9.2 3.8 0.0 4.3 3.7 40.9 3.1 3.8 1.8 3.7 4.5 4.3 8.2 7.5 8.1 3.8 5.8 3.0 6.4 6.2 1.2 5.1 3.2 2.9 0.0 5.1 3.5 10.3 7.9 12.7 17.2 0.5 6.2 6.8 5.5 3.9 CHCHD5 "C2orf9, MGC11104, MIC14, MIX14" ENSG00000125611 "Coiled-coil-helix-coiled-coil-helix domain containing 5" Q9BSY4 2 112584240-112589275 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038263 Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA038263: AB_10671525" "unprognostic (3.56e-2)" "unprognostic (3.41e-2)" "unprognostic (3.36e-2)" "unprognostic (4.57e-2)" "unprognostic (1.85e-1)" "unprognostic (7.75e-2)" "unprognostic (2.72e-1)" "unprognostic (7.18e-3)" "unprognostic (8.04e-2)" "unprognostic (4.96e-2)" "unprognostic (2.07e-1)" "unprognostic (4.95e-2)" "unprognostic (1.39e-2)" "unprognostic (3.91e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.12e-2)" 19.1 28.9 20.6 12.4 22.0 18.3 22.4 22.6 28.7 18.5 19.8 19.2 18.0 17.8 6.4 28.2 19.6 14.4 24.5 20.0 21.7 35.8 40.2 17.8 14.6 21.4 21.6 15.8 46.1 28.1 31.7 9.8 21.3 22.2 6.3 5.7 16.5 12.6 38.9 23.3 17.2 6.5 21.5 18.5 25.4 22.9 22.6 16.7 27.1 18.7 7.9 19.6 18.8 21.9 32.5 53.1 23.3 0.1 9.3 19.7 22.0 14.0 18.2 28.3 20.0 58.1 39.0 24.7 54.4 19.4 23.9 23.4 8.9 31.2 3.8 26.8 43.2 33.4 15.6 46.4 40.8 28.5 22.5 26.5 26.3 37.4 22.8 13.2 15.8 0.1 35.1 36.5 18.1 80.3 25.8 45.1 26.0 24.1 25.9 0.9 19.3 48.7 37.8 29.1 29.7 33.4 17.7 26.3 31.6 6.2 33.9 24.9 22.0 28.2 39.7 17.2 20.4 65.0 66.3 29.1 39.1 7.7 33.9 22.1 69.0 68.6 49.9 66.6 42.1 49.3 46.8 47.5 64.1 63.2 48.1 49.9 38.3 62.3 62.6 81.3 78.6 61.9 20.6 22.0 22.6 28.7 20.0 21.7 21.4 21.6 21.3 21.5 22.6 21.9 39.3 9.6 13.9 2.0 41.1 43.1 65.1 153.3 51.8 19.2 100.0 109.6 40.4 90.1 73.8 82.8 10.4 131.9 41.2 138.5 219.2 109.7 188.8 138.1 63.5 44.3 91.7 44.6 2.2 176.7 109.5 43.8 67.8 79.6 24.7 50.8 51.4 211.4 123.9 6.7 2.8 107.3 97.6 122.0 63.5 290.9 30.7 63.7 53.4 1.0 101.0 61.5 87.6 1.5 4.4 123.2 140.1 28.2 41.0 76.8 184.7 286.7 99.3 28.3 13.1 33.9 47.8 141.8 39.4 112.2 58.1 92.8 44.6 89.2 97.7 85.7 SLC20A1 "Glvr-1, GLVR1, PiT-1" ENSG00000144136 "Solute carrier family 20 member 1" Q8WUM9 2 112645939-112663825 "Metabolic proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Phosphate transport, Symport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 353.3;Paneth cells: 261.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 522.4;U-87 MG: 507.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019279, HPA035834" Approved Approved "Golgi apparatus" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "CAB019279: , HPA035834: AB_2674809" "unprognostic (1.81e-1)" "unprognostic (2.18e-1)" "unprognostic (5.38e-2)" "unprognostic (4.03e-3)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.56e-5)" "unprognostic (1.50e-2)" "unprognostic (3.38e-2)" "unprognostic (2.32e-2)" "unprognostic (1.39e-1)" "unprognostic (7.43e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (3.44e-5)" "unprognostic (6.85e-2)" "unprognostic (1.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-3)" 36.1 11.7 16.2 33.2 24.3 74.6 15.6 27.8 26.3 11.8 25.0 53.6 14.4 13.7 8.4 15.0 14.5 26.4 21.8 20.7 19.8 22.1 49.0 29.2 37.1 25.5 20.7 9.2 30.7 10.4 15.9 29.7 25.2 13.3 21.9 52.3 12.8 9.3 19.7 14.5 28.4 15.0 18.6 29.5 20.2 15.7 24.5 27.2 15.9 7.5 27.5 40.8 13.3 21.2 69.0 55.5 71.1 57.8 52.9 128.8 54.4 181.6 215.3 79.1 102.2 85.0 164.9 124.0 97.5 67.7 305.0 70.5 78.8 138.0 114.8 68.5 80.4 105.5 57.1 81.3 78.2 61.2 178.9 66.0 53.8 279.1 193.9 522.4 102.2 52.9 199.5 126.3 346.7 26.8 83.9 235.9 119.3 31.8 147.6 77.8 63.5 34.9 114.5 312.8 64.4 60.8 91.7 54.9 127.9 31.4 56.0 42.9 223.6 143.5 94.7 50.8 142.4 52.1 143.7 102.2 507.2 57.9 178.3 13.4 33.5 30.1 52.8 59.8 59.4 8.3 22.2 38.4 25.4 5.0 17.5 27.6 14.7 50.2 37.2 41.8 14.6 33.9 16.2 24.3 27.8 26.3 20.7 19.8 25.5 20.7 25.2 18.6 24.5 21.2 61.7 12.8 25.9 42.4 40.3 112.8 59.1 38.7 104.7 60.0 41.9 31.6 49.6 32.9 35.3 9.2 210.6 44.7 119.1 353.3 13.7 18.1 1.5 86.0 34.3 48.2 35.7 53.2 47.3 14.0 13.5 61.5 96.4 167.8 25.3 20.6 41.0 58.1 28.2 20.2 27.2 85.8 32.6 58.5 86.2 3.3 3.7 80.5 26.6 19.7 42.8 31.8 66.9 18.6 26.1 26.9 261.6 4.9 59.8 34.0 156.3 5.2 59.6 84.6 0.0 36.9 25.9 8.5 18.7 119.5 61.8 74.3 70.4 19.0 96.5 90.3 NT5DC4 ENSG00000144130 "5'-nucleotidase domain containing 4" Q86YG4 2 112721486-112742879 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.2" "Group enriched" "Detected in some" 11 "Early spermatids: 20.0;Late spermatids: 6.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "K-562: 16.1" "Not detected" "Not detected" HPA046856 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA046856: AB_2679841" "unprognostic (2.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-2)" "unprognostic (1.34e-2)" "unprognostic (2.20e-4)" "unprognostic (2.26e-1)" "unprognostic (3.66e-2)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (5.38e-4)" "unprognostic (1.38e-1)" "unprognostic (2.66e-1)" "unprognostic (1.60e-4)" "unprognostic (9.02e-2)" "unprognostic (1.33e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-4)" 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 1.0 0.3 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.6 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 1.2 0.0 0.0 0.1 2.2 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 20.0 0.3 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 13.1;lymphoid tissue: 12.1;testis: 4.5" "Cell type enhanced" "Detected in many" "Erythroid cells: 25.2;Granulosa cells: 12.5;Spermatocytes: 33.0;Spermatogonia: 35.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Cytosol" Yes Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Microtubules, Mitotic spindle" Cytosol "HPA039407: AB_10794091, HPA040057: AB_10794871, HPA070737: AB_2686303" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (4.69e-3)" "unprognostic (1.42e-3)" "unprognostic (1.69e-1)" "unprognostic (5.59e-2)" "unprognostic (5.75e-5)" "prognostic unfavorable (7.63e-4)" "unprognostic (2.49e-3)" "unprognostic (1.91e-1)" "unprognostic (9.57e-6)" "unprognostic (2.42e-1)" "unprognostic (0.00e+0)" "unprognostic (7.37e-2)" "unprognostic (1.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.49e-2)" 0.4 0.1 0.2 2.6 0.2 13.1 0.4 0.4 0.3 0.4 0.0 1.6 1.5 0.3 0.1 2.3 0.1 0.3 0.0 0.2 0.1 0.1 0.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.2 0.2 0.3 0.0 0.0 1.5 1.1 1.1 0.0 0.9 1.0 4.5 0.2 12.1 0.2 0.0 5.2 0.8 0.6 0.2 47.9 9.6 35.4 16.2 2.0 3.3 7.2 38.5 32.2 37.9 36.1 8.7 13.3 32.0 15.5 15.1 48.3 18.0 20.4 19.6 64.1 44.8 8.9 53.6 12.7 7.7 0.1 25.2 30.9 0.9 1.9 47.4 27.2 10.1 17.5 22.8 14.3 44.9 31.2 6.9 31.0 10.6 15.4 20.0 29.5 22.3 37.0 8.4 6.9 18.7 19.7 12.7 15.2 12.8 13.3 13.2 12.4 11.8 12.9 42.7 33.7 34.5 28.5 9.9 20.1 26.6 18.5 18.1 69.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.3 0.2 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 3.2 0.6 0.0 1.2 3.3 2.1 2.7 0.6 0.0 0.5 0.8 0.5 1.5 0.4 0.0 0.0 11.1 1.3 1.3 0.0 0.4 2.4 1.1 1.6 1.1 0.0 25.2 0.3 0.4 10.6 2.0 1.5 2.1 0.0 12.5 2.9 0.1 6.6 0.0 0.2 3.1 2.0 1.9 1.4 2.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.0 5.6 1.1 0.1 0.1 0.4 0.0 0.0 0.4 2.8 33.0 35.7 9.5 1.7 1.0 2.5 0.7 3.8 1.1 IL1A "IL-1A, IL1, IL1-ALPHA, IL1F1" ENSG00000115008 "Interleukin 1 alpha" P01583 2 112773925-112784493 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 13.3;testis: 10.4;urinary bladder: 26.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.6;Club cells: 9.8;Endometrial ciliated cells: 11.5;Glandular and luminal cells: 29.4;Macrophages: 30.6;Squamous epithelial cells: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 22.3;urothelial cancer: 17.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HBEC3-KT: 447.6;hTCEpi: 216.2;hTERT-HME1: 283.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 10800 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "unprognostic (3.41e-2)" "prognostic unfavorable (9.52e-4)" "unprognostic (1.99e-2)" "unprognostic (4.28e-2)" "unprognostic (2.08e-1)" "unprognostic (8.03e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-3)" "unprognostic (1.22e-1)" "unprognostic (4.30e-3)" "prognostic unfavorable (4.03e-4)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (8.62e-2)" 0.5 0.0 0.3 1.3 0.4 1.0 0.4 0.5 0.4 4.8 0.2 0.3 0.1 2.5 0.8 13.3 0.1 2.3 0.0 0.4 0.5 0.0 0.0 2.3 0.3 0.9 0.8 0.0 0.0 0.4 0.2 1.5 1.0 0.1 0.2 0.1 1.2 0.4 0.0 0.8 0.1 0.0 0.7 0.3 0.1 10.4 0.5 0.3 0.2 0.0 8.7 26.0 1.3 1.2 12.5 0.0 0.5 0.0 0.1 0.0 0.2 0.4 13.5 0.0 0.2 0.5 0.8 0.0 52.5 0.0 65.9 3.6 0.0 447.6 1.7 0.1 0.1 0.1 0.7 0.2 1.0 0.2 0.1 0.0 216.2 3.8 283.4 3.4 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.2 0.2 0.5 0.0 0.0 0.0 0.1 55.0 0.1 0.0 1.6 0.0 0.0 0.6 0.0 0.1 1.7 1.3 0.6 0.3 0.3 0.0 0.1 0.2 5.2 0.1 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.4 0.4 0.5 0.9 0.8 1.0 0.7 0.5 1.2 0.9 6.4 1.1 0.0 2.2 1.5 0.7 22.6 1.2 0.0 0.5 0.3 0.2 0.0 9.8 0.0 0.0 0.3 0.3 0.6 0.0 4.6 8.3 11.5 2.8 0.2 0.0 0.0 0.0 0.9 0.1 0.1 0.0 29.4 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.0 0.0 4.8 3.8 0.0 30.6 0.0 5.6 0.0 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.4 0.3 0.0 0.0 1.9 0.0 0.0 0.0 1.1 0.1 0.1 9.4 1.0 0.0 0.4 0.1 0.2 2.4 IL1B "IL-1B, IL1-BETA, IL1F2" ENSG00000125538 "Interleukin 1 beta" P01584 2 112829751-112836816 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cytokine, Mitogen, Pyrogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 201.7;urinary bladder: 126.2" "Group enriched" "Detected in many" 11 "Langerhans cells: 1451.9;Macrophages: 1510.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 94.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 94.1" "Cell line enhanced" "Detected in many" "BJ hTERT+: 649.3;HBEC3-KT: 293.3;HMC-1: 235.1;hTEC/SVTERT24-B: 319.1;hTERT-RPE1: 277.0;U-87 MG: 571.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 2330 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.55e-3)" "prognostic unfavorable (1.31e-4)" "unprognostic (2.75e-2)" "unprognostic (5.71e-2)" "unprognostic (1.34e-1)" "unprognostic (7.12e-2)" "unprognostic (2.63e-2)" "unprognostic (1.61e-2)" "unprognostic (1.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.72e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.49e-5)" "unprognostic (1.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.09e-2)" "unprognostic (4.01e-2)" 43.9 7.6 2.5 53.6 2.2 201.7 2.0 3.1 4.6 3.7 4.2 8.1 3.0 7.4 2.0 3.4 4.1 19.0 3.3 2.3 3.4 7.7 9.1 17.4 9.5 4.8 4.6 0.8 4.4 3.0 2.6 7.8 3.8 6.1 6.5 0.3 3.8 1.8 0.1 0.7 3.5 9.2 4.4 17.8 25.5 1.1 2.8 9.4 2.6 7.0 12.8 126.2 1.0 6.6 6.3 0.1 0.2 0.0 0.4 0.0 0.0 2.1 649.3 3.1 6.5 0.0 0.0 0.0 18.0 0.5 11.3 14.7 0.0 293.3 39.2 0.0 0.0 29.5 0.4 0.0 2.2 0.0 235.1 1.1 8.9 319.1 103.5 277.0 0.0 0.1 0.0 0.8 0.6 0.0 0.0 2.9 0.1 1.2 26.2 1.0 0.0 0.0 0.0 48.2 0.0 0.0 1.7 0.0 2.5 0.0 0.0 2.8 0.0 15.3 0.2 0.7 0.5 0.1 0.0 0.2 571.5 14.0 22.7 1.7 12.3 4.4 0.0 19.5 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 94.1 0.2 7.7 0.0 0.0 3.4 2.5 2.2 3.1 4.6 2.3 3.4 4.8 4.6 3.8 4.4 2.8 6.6 23.8 9.6 28.2 0.0 14.1 30.8 5.4 25.4 0.0 0.2 8.2 13.3 4.8 0.0 16.2 1.8 0.0 1.5 7.5 2.8 0.0 33.2 0.3 4.9 5.0 20.0 0.0 58.9 0.0 0.6 2.6 8.1 44.4 8.4 41.7 0.0 1.4 0.4 108.1 0.0 0.0 12.7 14.2 130.5 1451.9 0.7 0.0 1510.7 23.2 1.9 7.9 0.3 0.0 0.0 0.0 2.9 10.0 0.0 9.3 4.7 0.2 0.7 8.6 0.3 0.0 1.5 4.3 0.0 0.4 8.3 20.3 4.4 6.3 0.0 1.9 6.1 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL36A "FIL1, FIL1E, IL-1F6, IL1(EPSILON), IL1F6, MGC129552, MGC129553" ENSG00000136694 "Interleukin 36 alpha" Q9UHA7 2 113005459-113008044 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "esophagus: 411.3;lymphoid tissue: 115.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 8.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.2;MOLT-4: 1.2;U-266/70: 1.2" "Not detected" "Not detected" "Secreted to blood" NA NA 327000 "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.37e-1)" "unprognostic (9.66e-3)" "unprognostic (5.46e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.1 0.0 411.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 115.4 0.0 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36B "FIL1, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2, MGC126880, MGC126882" ENSG00000136696 "Interleukin 36 beta" Q9NZH7 2 113022089-113052867 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 2.2;lymphoid tissue: 3.8;skin 1: 8.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "GAMG: 71.8;U-87 MG: 73.3" "Not detected" "Not detected" HPA035664 Uncertain "Secreted to blood" NA NA 15300 "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "HPA035664: AB_10669672" "unprognostic (8.45e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-2)" "unprognostic (1.06e-1)" "unprognostic (3.77e-2)" "unprognostic (2.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.10e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 1.4 0.0 0.0 0.0 0.0 73.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL36RN "FIL1, FIL1(DELTA), FIL1D, IL-1F5, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, MGC29840" ENSG00000136695 "Interleukin 36 receptor antagonist" Q9UBH0 2 113058638-113065382 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 26.5;lymphoid tissue: 43.7;skin 1: 60.3" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 8.9;Extravillous trophoblasts: 2.0;Syncytiotrophoblasts: 3.8" "Cancer enriched" "Detected in some" 7 "head and neck cancer: 25.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "BEWO: 26.6;GAMG: 11.1;U-87 MG: 19.9" "Not detected" "Not detected" "Secreted to blood" NA NA 107000 "Cluster 31: Skin - Epidermis development" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "unprognostic (3.88e-3)" "unprognostic (3.16e-1)" "unprognostic (2.88e-1)" "unprognostic (4.29e-1)" "unprognostic (8.68e-3)" "unprognostic (9.80e-2)" "unprognostic (2.48e-1)" "unprognostic (5.99e-2)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" "unprognostic (5.37e-2)" "unprognostic (3.85e-3)" "unprognostic (4.23e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 3.4 0.0 0.0 0.0 0.0 4.6 0.0 0.1 60.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 43.7 0.0 9.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.1 1.1 0.3 0.0 0.0 11.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 19.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.0 0.0 0.0 0.7 IL1F10 "FKSG75, IL-1F10, IL-1HY2, IL1-theta, MGC11983, MGC119832, MGC119833" ENSG00000136697 "Interleukin 1 family member 10" Q8WWZ1 2 113067970-113075843 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "skin 1: 12.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 222000 "Cluster 61: Skin - Cornification" "unprognostic (3.89e-1)" "unprognostic (6.25e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (2.42e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 IL1RN "ICIL-1RA, IL-1RN, IL1F3, IL1RA, IRAP, MGC10430" ENSG00000136689 "Interleukin 1 receptor antagonist" P18510 2 113107214-113134016 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 1969.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 184.4;Hofbauer cells: 306.0;Langerhans cells: 292.6;Squamous epithelial cells: 469.7;Suprabasal keratinocytes: 336.6;Urothelial cells: 464.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 92.7" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 63.8;myeloid DC: 61.7;neutrophil: 240.2" "Group enriched" "Detected in many" 694 "dendritic cells: 61.7;granulocytes: 240.2;monocytes: 63.8" "Cell line enhanced" "Detected in some" "A-431: 59.1;HaCaT: 112.3;RT4: 106.6;THP-1: 27.3" "Not detected" "Not detected" "HPA001482, CAB009633" Enhanced Approved Nucleoplasm,Centrosome,Cytosol "Secreted to blood" NA NA 291000 45000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Centrosome, Cytosol" "CAB009633: AB_2125576, HPA001482: AB_1078437" "unprognostic (3.85e-3)" "unprognostic (3.96e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.21e-1)" "unprognostic (3.63e-2)" "unprognostic (3.15e-2)" "unprognostic (2.55e-1)" "unprognostic (4.46e-2)" "unprognostic (9.54e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (5.59e-3)" "prognostic unfavorable (2.66e-6)" "unprognostic (2.05e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" 13.0 2.1 0.2 46.7 0.4 233.3 9.0 0.4 1.3 278.1 1.1 4.4 10.7 2.5 2.9 1969.7 2.1 17.0 2.5 0.3 0.3 1.6 248.5 20.1 1.4 0.4 0.5 0.9 1.8 2.0 2.3 21.1 0.8 2.4 4.0 0.0 287.1 7.5 0.8 128.6 8.8 3.9 0.8 14.7 45.5 6.4 1.3 5.2 6.4 3.0 311.7 185.7 465.0 0.6 59.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.2 0.0 0.6 0.2 0.2 0.0 1.1 112.3 0.0 3.3 0.0 0.1 0.0 0.3 0.0 17.3 0.0 0.3 20.3 0.0 14.3 0.7 0.0 2.0 0.0 0.0 0.3 0.3 0.0 0.5 0.1 14.7 0.0 13.2 0.0 0.0 0.1 0.1 0.0 106.6 0.0 0.0 0.1 0.8 0.1 0.0 0.0 27.3 0.3 1.4 0.0 0.7 0.1 0.6 0.1 0.2 10.3 10.5 0.3 0.0 63.8 1.9 0.0 27.7 0.0 0.1 0.0 0.0 61.7 0.1 0.1 0.1 240.2 0.0 13.7 0.8 0.1 19.8 0.2 0.4 0.4 1.3 0.3 0.3 0.4 0.5 0.8 0.8 1.3 0.6 1.7 6.4 7.7 0.0 4.1 184.4 81.3 151.8 56.9 0.0 4.9 3.4 0.4 11.5 60.6 3.7 0.0 1.8 0.2 6.5 0.0 27.5 34.8 7.8 1.4 4.8 0.0 3.2 0.3 28.0 2.9 11.0 44.4 23.6 10.1 0.0 3.3 53.0 306.0 0.0 0.2 1.1 6.1 39.8 292.6 93.3 0.6 111.1 24.9 0.0 22.6 0.0 2.1 0.5 0.2 149.9 0.1 0.4 2.8 58.4 9.3 0.2 20.2 0.0 0.0 0.3 3.8 0.8 0.2 469.7 336.6 4.5 3.3 0.0 3.2 464.9 PSD4 "EFA6B, TIC" ENSG00000125637 "Pleckstrin and Sec7 domain containing 4" Q8NDX1 2 113157325-113209396 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 51.2;Proximal enterocytes: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 9.8;NB-4: 9.3" "Low region specificity" "Detected in single" "HPA034722, HPA077847" Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "HPA034722: AB_10669730, HPA077847: " "unprognostic (1.87e-3)" "unprognostic (1.32e-2)" "unprognostic (2.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.21e-2)" "unprognostic (1.13e-3)" "prognostic favorable (9.91e-5)" "unprognostic (6.56e-2)" "unprognostic (4.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-2)" "prognostic favorable (4.00e-4)" "unprognostic (8.12e-2)" "unprognostic (2.41e-1)" "unprognostic (3.60e-3)" 1.7 13.7 1.4 3.1 1.3 3.7 3.9 0.5 1.2 2.3 0.7 7.0 2.0 0.7 4.0 10.8 1.7 1.3 0.8 1.0 1.0 5.2 21.2 5.8 3.9 1.0 0.8 0.5 11.6 3.0 3.4 0.9 1.1 8.7 1.9 0.5 11.3 1.2 0.6 9.0 17.7 0.4 0.9 23.3 12.4 1.5 1.5 5.9 10.1 0.3 4.0 3.7 4.2 0.9 5.7 1.0 0.3 0.1 0.0 0.0 6.1 0.4 2.2 0.4 0.5 1.5 8.1 9.8 1.2 0.2 1.7 7.4 0.0 2.0 0.1 8.3 0.1 4.1 0.8 2.2 0.1 6.9 6.9 0.1 1.9 0.2 0.5 0.9 0.0 3.8 3.9 4.1 0.0 3.2 7.1 9.3 0.1 1.8 1.1 0.1 0.1 4.3 0.4 1.4 0.5 0.0 0.7 5.1 0.0 0.2 1.6 5.6 0.1 0.3 0.2 0.2 1.6 5.0 4.0 3.0 0.9 3.3 0.1 1.7 0.9 1.7 2.0 0.6 1.7 1.0 1.5 1.8 0.6 1.2 1.7 1.9 3.9 2.4 0.7 1.5 1.1 1.4 1.4 1.3 0.5 1.2 1.0 1.0 1.0 0.8 1.1 0.9 1.5 0.9 0.9 19.2 12.0 7.5 28.6 12.7 10.4 7.6 13.1 0.3 22.5 11.2 1.8 11.5 5.8 33.1 0.0 20.7 41.6 39.1 0.0 21.3 0.3 9.0 1.6 2.1 7.2 13.0 0.9 23.6 11.2 3.0 31.1 20.4 3.8 2.9 2.9 51.2 12.1 3.3 1.7 10.7 4.1 13.8 17.0 0.9 0.9 14.3 1.8 2.8 13.8 10.1 47.4 2.5 0.2 23.1 17.8 0.0 18.3 15.8 50.3 7.1 4.6 0.4 0.0 3.0 1.7 0.2 1.1 17.4 15.8 7.5 28.2 1.7 18.6 11.1 PAX8 ENSG00000125618 "Paired box 8" Q06710 2 113215997-113278921 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "kidney: 267.9;thyroid gland: 565.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 246.5;Endometrial ciliated cells: 114.0;Glandular and luminal cells: 228.2;Proximal tubular cells: 128.1" "Group enriched" "Detected in many" 12 "endometrial cancer: 60.6;ovarian cancer: 63.5;renal cancer: 33.2;thyroid cancer: 122.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 7 "EFO-21: 79.7;GAMG: 50.0;RPTEC TERT1: 193.2" "Region enriched" "Detected in some" 4 "pons and medulla: 5.5" "HPA030062, CAB055097, CAB061888, HPA064554" Enhanced Enhanced Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB055097: AB_2236705, CAB061888: AB_10895719, HPA030062: AB_10603982, HPA064554: AB_2685283" "unprognostic (2.63e-3)" "unprognostic (3.80e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (1.75e-5)" "unprognostic (7.24e-2)" "unprognostic (5.16e-5)" "unprognostic (1.56e-2)" "unprognostic (3.29e-2)" "unprognostic (1.03e-1)" "unprognostic (2.16e-1)" "unprognostic (4.13e-2)" "unprognostic (4.00e-2)" "unprognostic (3.37e-2)" "unprognostic (3.27e-1)" "unprognostic (2.37e-1)" "unprognostic (8.93e-3)" "unprognostic (1.02e-1)" 2.0 6.0 1.4 0.6 0.9 0.5 1.7 0.1 1.1 14.5 1.7 1.8 0.6 8.8 32.9 2.2 37.5 3.6 2.1 1.0 1.9 267.9 1.2 1.6 1.7 5.2 1.3 1.7 1.0 1.4 1.4 1.9 3.0 1.1 0.9 1.5 1.9 26.1 0.5 1.8 2.4 0.8 3.7 0.8 1.4 2.4 2.3 0.5 565.5 0.3 1.0 2.1 1.0 1.9 9.4 0.8 0.4 0.0 0.4 0.2 3.0 2.6 8.0 0.7 1.2 5.7 1.6 1.7 79.7 0.6 50.0 0.1 1.6 2.6 0.7 3.9 0.0 1.5 0.7 3.4 0.9 0.0 0.0 2.3 0.3 0.6 1.9 9.9 0.1 0.0 1.3 6.2 2.5 1.8 1.0 3.8 0.5 2.2 5.5 0.0 0.6 2.1 193.2 14.4 1.5 0.0 10.4 0.1 5.6 0.0 0.0 3.5 2.7 13.8 0.5 2.6 7.2 1.2 4.6 0.6 11.9 2.0 0.0 0.7 1.0 0.0 0.1 0.6 0.4 1.3 0.4 0.3 0.9 0.5 0.7 0.4 0.2 0.6 0.4 0.3 0.2 0.4 1.4 0.9 0.1 1.1 1.0 1.9 5.2 1.3 3.0 3.7 2.3 1.9 1.3 3.2 2.0 0.7 4.1 0.6 1.9 1.8 7.4 0.6 2.0 1.4 0.9 5.7 3.4 246.5 0.0 2.4 1.6 9.5 46.9 8.5 1.6 114.0 21.8 1.4 4.8 3.0 0.8 2.9 2.4 1.6 4.1 228.2 0.0 1.0 1.1 0.3 5.2 0.0 0.8 3.2 2.0 2.6 2.1 3.9 5.0 5.6 0.0 0.0 2.0 4.0 1.0 0.5 0.2 29.2 7.4 0.4 0.5 1.6 6.3 128.1 0.6 0.9 6.6 3.6 1.7 6.2 7.3 12.5 0.9 0.8 3.1 0.4 3.7 2.2 IGKV1OR2-108 "IGKV1/OR2-108, IGKV1OR2108, IGO1" ENSG00000231292 "Immunoglobulin kappa variable 1/OR2-108 (non-functional)" 2 113406396-113406872 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 38.2;lymphoid tissue: 56.7" "Cell type enriched" "Detected in single" 652 "Plasma cells: 65.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "memory B-cell: 13.5;naive B-cell: 12.2" "Lineage enriched" "Detected in single" 58 "B-cells: 13.5" "Cell line enhanced" "Detected in some" "Daudi: 6.6;HBEC3-KT: 7.2;hTEC/SVTERT24-B: 4.1;REH: 4.1" "Not detected" "Not detected" HPA048721 Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "HPA048721: " "prognostic favorable (1.53e-6)" "unprognostic (2.73e-2)" "unprognostic (1.55e-2)" "unprognostic (3.37e-1)" "unprognostic (3.64e-3)" "unprognostic (3.57e-2)" "unprognostic (3.20e-1)" "unprognostic (5.21e-2)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (9.96e-6)" "unprognostic (6.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.76e-1)" "unprognostic (1.95e-1)" 0.5 1.4 0.1 23.3 0.4 11.2 16.7 0.0 0.3 4.8 5.6 38.2 21.8 0.3 0.0 6.8 0.4 5.5 0.2 0.8 0.0 0.1 1.4 6.9 14.0 0.1 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.9 22.1 0.1 15.2 0.5 0.1 4.8 13.9 0.8 0.0 12.7 16.9 0.0 0.1 3.8 1.3 0.0 56.7 21.7 0.1 0.0 2.1 0.7 0.3 0.0 0.0 0.0 0.4 0.0 2.2 0.3 1.5 3.0 1.2 6.6 0.0 0.9 1.1 0.3 0.0 7.2 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 4.1 2.4 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.6 0.4 0.0 1.6 4.1 0.6 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.6 0.0 1.3 0.2 0.2 0.1 1.2 0.1 0.4 0.4 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 13.5 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 0.1 0.4 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 FOXD4L1 FOXD5 ENSG00000184492 "Forkhead box D4 like 1" Q9NU39 2 113498665-113501155 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 1.1" "Cell type enriched" "Detected in some" 11 "monocytes: 31.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.5" "HPA012836, HPA069839" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm Cytosol "HPA012836: AB_2105429, HPA069839: " "unprognostic (3.48e-1)" "unprognostic (3.66e-2)" "unprognostic (3.02e-2)" "unprognostic (6.61e-2)" "unprognostic (3.22e-1)" "unprognostic (6.41e-4)" "unprognostic (2.54e-1)" "unprognostic (5.77e-3)" "unprognostic (5.93e-2)" "unprognostic (4.21e-2)" "unprognostic (9.54e-4)" "unprognostic (3.98e-2)" "unprognostic (1.18e-8)" "unprognostic (1.57e-2)" "unprognostic (4.14e-2)" "unprognostic (9.57e-2)" "unprognostic (5.91e-4)" 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.3 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.2 0.3 0.2 0.0 0.5 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.3 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 1.5 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.5 0.1 0.3 0.4 0.4 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.5 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 RABL2A ENSG00000144134 "RAB, member of RAS oncogene family like 2A" Q9UBK7 2 113627229-113643396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 19.8" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 10.6" "HPA042642, HPA042700, HPA044007" Approved Approved Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Centrosome Vesicles "HPA042642: , HPA042700: AB_2678120, HPA044007: AB_2678770" "unprognostic (7.76e-3)" "unprognostic (7.79e-3)" "unprognostic (7.00e-2)" "unprognostic (2.94e-2)" "unprognostic (1.99e-1)" "unprognostic (4.23e-2)" "unprognostic (4.89e-2)" "unprognostic (6.77e-3)" "unprognostic (6.61e-2)" "unprognostic (7.36e-2)" "unprognostic (5.78e-3)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.89e-2)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (3.19e-5)" 2.5 1.2 2.7 1.3 2.9 0.9 2.8 2.3 3.4 3.8 4.6 3.3 1.3 4.4 3.6 1.5 19.8 1.6 2.4 3.0 2.5 2.0 1.9 2.7 1.0 2.6 4.8 5.0 1.5 1.3 2.9 0.8 3.2 2.7 1.0 6.6 2.1 2.0 1.3 2.5 1.8 2.1 3.3 1.7 1.9 5.3 2.9 3.0 3.5 1.4 1.9 2.6 2.8 2.7 2.1 3.7 5.0 4.0 4.1 5.8 3.7 2.0 1.6 2.9 2.0 3.3 1.4 3.1 8.5 0.7 2.0 2.3 2.5 0.3 1.9 4.1 4.7 1.6 0.1 0.4 3.3 0.6 1.1 2.1 4.3 0.5 1.2 4.2 2.1 4.6 1.5 0.8 1.7 1.8 10.6 0.7 2.8 1.9 1.3 2.0 1.9 1.3 2.1 0.5 2.0 7.0 1.9 2.2 1.9 1.5 0.4 3.0 0.5 0.4 0.6 0.7 1.4 2.9 3.4 0.8 5.8 2.3 1.0 0.0 4.3 2.4 6.2 7.1 6.9 8.9 9.0 6.5 7.1 8.2 7.5 5.7 0.5 12.8 7.1 9.1 4.9 5.4 2.7 2.9 2.3 3.4 3.0 2.5 2.6 4.8 3.2 3.3 2.9 2.7 4.2 9.6 8.1 13.4 6.4 4.5 5.6 8.1 5.2 7.6 6.4 8.0 9.5 2.8 12.1 7.3 10.4 3.4 6.3 4.9 13.7 7.6 16.3 36.9 5.6 3.4 7.2 3.0 30.2 3.1 2.9 6.8 5.6 2.8 11.4 9.9 5.3 4.4 3.6 16.8 20.5 4.3 4.1 3.2 3.5 14.5 8.1 3.1 7.2 3.7 5.7 7.3 9.2 7.1 19.4 3.6 3.2 7.2 0.8 2.9 7.2 6.8 123.2 16.8 0.0 5.9 8.1 22.3 9.6 3.6 4.8 2.5 6.0 4.4 4.1 3.6 SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA034828: AB_2674350, HPA049229: AB_2680682" "unprognostic (1.59e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (8.37e-2)" "unprognostic (3.87e-3)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (4.83e-2)" 9.8 22.8 4.6 6.0 5.9 8.0 14.3 12.0 6.6 9.3 31.5 14.7 13.7 10.3 11.5 11.1 8.0 11.1 11.0 6.1 6.4 18.0 14.6 9.9 9.0 6.7 4.8 12.4 15.1 17.4 5.2 11.1 7.1 11.2 13.6 14.1 9.8 6.9 12.3 20.3 12.9 8.9 5.4 10.1 12.9 7.1 5.2 5.7 23.7 11.2 10.0 8.0 6.3 12.0 9.7 9.6 7.7 4.9 48.6 36.8 14.0 15.9 13.2 7.7 12.9 24.3 18.9 18.5 22.1 21.9 21.3 8.7 12.2 12.5 17.9 5.7 4.9 9.7 9.6 19.7 20.8 12.8 24.0 46.8 17.4 17.9 25.9 22.1 15.2 4.6 7.7 11.2 19.1 8.5 5.6 14.0 3.6 15.0 5.2 6.5 13.1 9.7 52.5 15.8 2.1 6.0 12.9 14.5 11.5 12.8 9.4 12.6 12.7 14.3 6.3 9.2 6.7 9.7 8.7 8.2 16.8 8.9 13.6 2.9 0.7 0.6 0.5 0.8 0.6 0.9 0.5 0.4 0.6 1.2 0.6 0.6 2.1 1.0 1.2 0.9 0.9 0.6 4.6 5.9 12.0 6.6 6.1 6.4 6.7 4.8 7.1 5.4 5.2 12.0 18.9 22.4 19.8 39.5 18.0 25.4 31.1 20.0 31.9 10.3 20.4 9.8 25.4 21.5 30.4 73.5 22.9 46.3 11.6 44.1 11.7 28.7 28.3 32.4 21.9 15.4 14.5 9.9 43.4 28.5 72.0 24.8 28.5 38.6 24.1 14.4 12.5 20.8 28.3 5.0 47.0 25.6 12.2 13.4 17.2 15.6 12.5 14.6 8.8 39.4 15.5 21.0 7.2 65.4 83.2 23.1 29.7 13.9 37.5 35.3 47.9 45.1 26.3 19.6 0.0 14.2 22.7 60.0 20.5 32.7 34.0 66.4 10.8 41.0 24.8 35.1 ACTR3 ARP3 ENSG00000115091 "Actin related protein 3" P61158 2 113890063-113962596 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005085, HPA047016, HPA051683" Approved NA NA 25000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "CAB005085: AB_2289106, HPA047016: AB_2679903, HPA051683: AB_2681573" "unprognostic (7.28e-2)" "prognostic unfavorable (6.52e-5)" "unprognostic (2.03e-2)" "unprognostic (1.01e-3)" "unprognostic (1.14e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (9.27e-3)" "unprognostic (1.63e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.81e-5)" "unprognostic (2.57e-1)" "unprognostic (2.54e-2)" "unprognostic (3.44e-2)" "unprognostic (4.44e-1)" 97.5 125.3 29.9 229.7 36.4 216.5 64.5 37.6 41.0 62.7 52.4 129.3 107.4 78.1 47.2 167.1 58.1 84.4 71.7 48.0 41.9 79.4 89.9 97.9 291.2 46.4 38.2 46.4 64.3 54.7 23.1 101.4 41.7 71.3 125.1 31.7 64.3 83.6 47.8 77.7 119.0 137.0 36.2 155.8 113.1 84.8 39.0 185.8 67.3 49.8 331.3 153.6 67.1 46.7 377.8 179.1 249.4 170.6 178.0 251.7 259.9 518.7 395.0 369.7 349.1 379.9 233.6 538.7 590.6 487.9 497.1 200.0 262.3 286.5 486.7 806.2 135.6 502.7 210.2 296.2 314.8 474.0 879.1 227.1 220.8 484.9 316.5 216.1 348.6 207.1 273.9 393.8 493.1 153.2 429.7 204.5 187.2 254.8 297.5 328.8 246.8 273.4 381.0 348.9 124.0 124.1 263.0 269.7 330.6 188.7 112.7 387.7 514.6 440.9 288.3 205.6 451.5 208.5 446.5 635.4 385.5 304.2 417.7 753.0 478.9 1048.4 464.4 728.1 381.6 455.9 424.6 460.6 634.4 385.0 371.4 437.9 777.1 479.9 887.7 191.4 587.0 1265.4 29.9 36.4 37.6 41.0 48.0 41.9 46.4 38.2 41.7 36.2 39.0 46.7 113.7 89.8 64.1 26.4 254.0 331.9 369.7 139.1 93.9 32.0 57.5 48.9 68.5 57.2 125.4 68.0 8.4 144.6 196.5 164.4 129.1 220.8 113.6 109.2 100.8 138.9 85.3 154.8 40.1 154.8 316.6 101.4 122.9 171.0 267.5 88.4 81.0 72.9 339.2 38.7 40.4 120.2 105.8 201.4 413.7 108.3 45.4 288.1 112.1 69.3 316.5 46.7 286.3 58.3 67.6 177.0 168.1 73.0 158.7 181.7 103.3 132.4 117.7 19.5 65.7 58.5 194.1 207.1 74.7 173.4 353.8 205.6 264.4 242.2 120.3 314.1 DPP10 "DPL2, DPPY, DPRP3" ENSG00000175497 "Dipeptidyl peptidase like 10" Q8N608 2 114442299-115845780 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Asthma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 10.7;brain: 20.2;pancreas: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 4634.9;Excitatory neurons: 3067.4;Inhibitory neurons: 3258.7;Oligodendrocyte precursor cells: 990.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.1;HAP1: 6.2;HMC-1: 4.3;JURKAT: 3.4;NTERA-2: 3.7;RT4: 6.7;SCLC-21H: 9.7;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048767 Uncertain NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA048767: AB_2680515" "unprognostic (1.19e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-2)" "unprognostic (1.29e-1)" "unprognostic (2.03e-2)" "unprognostic (6.59e-2)" "unprognostic (2.92e-1)" "unprognostic (5.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (7.61e-2)" "unprognostic (4.22e-2)" 0.2 10.7 12.4 0.3 20.2 0.1 0.0 0.0 16.6 0.3 0.0 2.2 1.2 0.4 0.0 0.0 0.1 0.8 0.1 19.3 0.5 0.2 0.1 0.2 0.0 1.9 3.1 0.0 17.3 0.0 0.8 0.8 2.0 0.0 2.8 4.1 0.2 0.0 0.0 0.1 1.2 0.8 4.5 0.0 1.0 1.0 6.0 0.0 0.6 0.0 0.0 0.3 0.0 11.7 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 6.7 9.7 3.9 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 20.2 0.0 16.6 19.3 0.5 1.9 3.1 2.0 4.5 6.0 11.7 0.0 0.0 0.0 4634.9 0.0 0.0 0.0 0.0 0.6 21.7 0.0 0.0 1.5 4.3 0.6 0.0 0.0 1.5 0.0 2.3 0.0 0.0 12.4 0.1 0.1 0.1 4.2 2.1 3067.4 2.7 10.2 0.5 0.0 0.3 0.0 5.8 0.7 0.0 0.3 5.0 3258.7 1.4 0.0 0.0 0.0 5.7 0.3 0.0 1.8 58.1 0.0 1.4 0.0 990.7 48.3 0.8 1.9 0.0 0.0 0.0 0.2 0.2 0.0 0.7 0.0 0.0 0.1 1.6 2.6 0.3 0.0 4.4 0.0 0.4 3.2 0.0 DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814691-117832377 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 376.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: AB_10672091, HPA041056: AB_2677277" "unprognostic (1.44e-1)" "unprognostic (2.22e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.64e-4)" "unprognostic (2.06e-1)" "unprognostic (1.77e-3)" "prognostic unfavorable (3.07e-4)" "unprognostic (8.80e-2)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-2)" "unprognostic (4.94e-2)" "unprognostic (8.51e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (7.28e-2)" "unprognostic (5.65e-2)" 25.3 21.4 14.9 30.2 15.9 21.8 32.7 16.1 18.0 23.4 15.1 28.3 22.4 30.0 22.9 24.8 23.6 22.2 21.2 14.1 15.9 27.0 35.2 24.8 41.1 15.7 15.2 25.5 21.1 21.4 10.8 26.2 16.1 23.2 31.0 19.4 19.3 23.0 18.6 22.9 23.4 26.3 16.6 32.3 22.8 20.6 15.1 34.5 30.2 18.3 41.7 33.2 17.3 19.0 94.0 41.9 61.3 55.5 35.5 31.9 101.0 54.7 43.0 73.7 64.6 104.2 60.6 137.8 85.9 45.6 68.0 71.1 120.3 70.7 108.0 70.6 83.9 132.0 36.9 105.1 49.5 178.4 66.0 33.4 63.9 93.7 94.3 37.6 44.9 70.3 146.5 58.4 57.1 58.6 98.2 92.6 154.4 79.1 62.3 84.4 95.8 121.3 48.8 55.2 58.8 99.3 62.7 69.2 73.4 62.1 43.9 96.7 34.9 65.6 96.5 46.8 99.5 66.3 87.9 376.0 48.2 82.9 30.1 11.7 23.0 16.3 24.9 28.9 32.0 37.4 29.8 28.9 20.7 30.3 35.6 31.7 5.8 29.7 33.1 33.7 25.7 32.1 14.9 15.9 16.1 18.0 14.1 15.9 15.7 15.2 16.1 16.6 15.1 19.0 144.4 96.1 62.5 24.8 153.9 192.7 114.4 149.4 100.2 150.5 82.8 94.5 50.4 101.5 103.8 121.4 83.4 110.3 140.6 69.0 117.4 125.4 17.1 92.2 125.1 109.1 56.9 76.4 24.3 115.2 120.9 98.2 63.2 102.8 110.3 71.8 107.1 195.6 87.9 82.4 28.0 108.0 109.9 104.8 100.8 17.7 106.6 100.6 92.5 20.6 117.1 70.3 135.9 26.7 39.1 130.0 68.8 103.8 103.3 118.1 53.3 186.5 90.6 132.9 65.7 158.7 110.1 138.6 129.9 81.4 160.5 88.8 143.2 67.4 114.6 65.3 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 INSIG2 ENSG00000125629 "Insulin induced gene 2" Q9Y5U4 2 118088452-118110997 "Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033861 Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB033861: AB_2249149" "unprognostic (3.84e-3)" "unprognostic (4.54e-3)" "unprognostic (1.84e-1)" "unprognostic (7.00e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-1)" "unprognostic (7.30e-2)" "unprognostic (7.41e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (2.40e-1)" "prognostic unfavorable (4.11e-6)" "unprognostic (1.40e-1)" "unprognostic (2.65e-1)" "unprognostic (1.42e-1)" "unprognostic (3.75e-2)" 10.4 6.2 5.0 5.7 5.4 3.8 8.5 7.3 6.3 8.7 7.2 8.8 9.6 9.4 8.9 6.6 7.0 8.2 8.5 7.1 5.1 12.3 28.0 10.3 7.3 5.4 5.8 10.3 11.7 12.4 7.0 9.0 5.7 8.0 7.3 8.9 8.5 6.3 7.8 10.2 9.7 8.8 5.3 11.3 12.6 6.3 6.4 9.6 10.6 6.8 9.1 7.3 8.1 5.5 33.0 7.7 9.2 4.8 26.1 13.2 11.7 9.0 10.2 7.5 13.7 6.7 32.8 6.3 31.6 12.8 14.6 13.5 8.0 17.9 14.6 13.2 11.1 6.6 8.8 38.2 6.0 8.8 9.9 17.5 14.2 8.3 14.6 22.7 18.3 9.7 3.8 11.3 11.4 4.2 9.4 6.0 4.4 10.5 10.0 6.3 7.6 7.2 12.1 12.0 7.5 8.8 5.5 9.0 5.2 10.2 4.4 6.0 21.1 10.9 7.9 8.5 4.5 16.3 12.3 6.5 17.4 6.4 6.6 6.6 6.8 12.3 7.2 10.4 8.2 7.7 7.2 6.8 7.4 6.4 8.0 9.1 7.0 9.3 11.6 7.1 7.1 6.0 5.0 5.4 7.3 6.3 7.1 5.1 5.4 5.8 5.7 5.3 6.4 5.5 9.6 35.3 28.9 17.3 30.9 40.9 13.4 98.8 13.6 14.9 26.1 10.7 19.5 62.9 36.9 44.1 12.5 20.0 26.7 13.5 19.6 89.7 4.1 11.8 10.2 18.1 20.9 12.6 27.7 62.1 37.7 18.6 15.8 18.5 21.0 10.9 42.8 48.7 29.7 25.2 25.1 13.1 34.6 23.6 46.3 4.3 12.8 19.0 32.0 20.6 23.4 22.8 16.5 27.2 20.5 92.5 14.4 14.3 50.8 25.3 34.4 29.6 23.9 12.4 0.0 21.3 30.1 38.1 16.1 11.6 40.1 19.8 21.5 8.4 13.2 32.1 EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.2;skeletal muscle: 13.9;skin 1: 10.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 5.6;Fibroblasts: 4.8;Melanocytes: 12.4;Skeletal myocytes: 12.0;Smooth muscle cells: 5.4" "Cancer enhanced" "Detected in many" "breast cancer: 5.6" "Region enriched" "Detected in many" 6 "midbrain: 18.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.1;ASC TERT1: 7.2;fHDF/TERT166: 13.3;HSkMC: 13.5;PC-3: 7.8;U-138 MG: 9.9;U-2197: 11.2" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 23.6" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: AB_2686573" "unprognostic (5.20e-2)" "unprognostic (1.61e-1)" "unprognostic (5.78e-2)" "unprognostic (4.84e-7)" "unprognostic (1.87e-3)" "unprognostic (1.90e-1)" "unprognostic (1.95e-3)" "unprognostic (1.16e-1)" "unprognostic (2.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.46e-1)" "unprognostic (3.38e-9)" "unprognostic (2.15e-2)" "unprognostic (1.88e-1)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" 3.5 0.2 0.1 0.0 0.1 0.0 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 18.2 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 13.9 10.4 0.0 0.0 0.5 0.0 0.0 0.1 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.5 4.0 0.2 0.6 0.2 16.1 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 4.7 0.5 0.6 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 2.3 0.0 0.0 0.0 9.9 1.0 11.2 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.5 0.7 18.2 3.2 0.5 1.4 0.5 1.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 5.6 2.8 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 12.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 5.4 0.1 0.4 0.0 2.6 0.0 0.2 0.0 0.0 0.0 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 C1QL2 "C1QTNF10, CTRP10" ENSG00000144119 "Complement C1q like 2" Q7Z5L3 2 119156243-119158751 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 26.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 28.3;Cone photoreceptor cells: 8.4;Oligodendrocyte precursor cells: 37.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 2.6" "Region enhanced" "Detected in many" "hippocampal formation: 22.7" "Low region specificity" "Detected in many" HPA057934 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "HPA057934: AB_2683558" "unprognostic (6.95e-2)" "unprognostic (9.74e-2)" "unprognostic (4.48e-3)" "unprognostic (1.08e-1)" "unprognostic (9.91e-4)" "unprognostic (2.60e-5)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" 0.0 0.0 17.6 0.0 9.4 0.0 0.2 3.9 17.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 26.5 16.3 0.0 0.0 0.0 0.1 7.3 7.0 0.1 0.0 0.0 0.5 0.0 6.1 0.0 0.0 2.9 0.0 0.0 0.0 0.4 0.0 0.0 4.5 0.0 0.0 0.2 20.3 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 9.4 3.9 17.0 26.5 16.3 7.3 7.0 6.1 4.5 20.3 8.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 28.3 1.3 0.8 0.5 0.0 0.0 0.0 8.4 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 37.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 STEAP3 "dudlin-2, STMP3, TSAP6" ENSG00000115107 "STEAP3 metalloreductase" Q658P3 2 119223831-119265652 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 189.5;parathyroid gland: 78.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.3;Exocrine glandular cells: 36.2;Hepatocytes: 91.6;Respiratory ciliated cells: 36.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.4;intermediate monocyte: 2.7;myeloid DC: 4.1;NK-cell: 1.3" "Group enriched" "Detected in many" 6 "dendritic cells: 4.1;monocytes: 2.7;NK-cells: 1.3" "Cell line enhanced" "Detected in many" "U-87 MG: 149.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA050510 Approved Approved Nucleoli,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Nucleoli "HPA050510: AB_2681151" "unprognostic (6.51e-2)" "unprognostic (6.48e-2)" "unprognostic (4.89e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-3)" "unprognostic (9.07e-2)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (9.75e-2)" "unprognostic (1.58e-3)" "unprognostic (5.08e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.82e-1)" "unprognostic (4.45e-1)" "unprognostic (9.37e-2)" "unprognostic (6.82e-2)" 9.1 6.3 4.3 3.9 3.7 16.9 14.5 7.1 4.6 16.7 10.6 9.5 22.1 3.6 5.3 15.8 7.7 2.3 9.5 7.0 7.5 6.9 189.5 9.1 0.9 14.4 9.4 4.4 27.1 78.9 13.8 11.3 12.8 11.8 6.9 0.7 34.3 7.5 29.9 9.0 10.9 3.1 7.6 1.8 22.5 1.9 7.2 2.2 5.4 12.5 3.1 7.0 7.2 12.7 21.8 25.6 0.0 8.7 12.1 112.9 22.1 6.8 7.4 13.1 11.8 19.5 29.0 0.1 49.9 38.5 94.1 35.9 11.1 22.4 14.9 0.1 35.9 42.1 22.2 38.8 30.0 10.5 7.7 67.3 38.7 78.0 27.7 89.8 11.4 0.0 20.9 4.2 37.6 20.6 0.1 6.2 34.2 33.3 52.7 0.2 14.7 18.5 16.2 54.1 41.9 7.7 18.8 64.1 4.9 4.9 12.7 13.7 49.6 81.2 46.8 17.4 37.4 0.1 0.1 0.2 149.1 26.2 17.2 0.0 2.4 0.4 0.1 2.7 0.0 0.4 0.0 0.0 4.1 0.1 0.0 0.0 0.0 1.3 0.4 0.2 0.0 1.0 4.3 3.7 7.1 4.6 7.0 7.5 14.4 9.4 12.8 7.6 7.2 12.7 9.1 0.0 7.9 2.3 1.0 2.0 7.4 11.9 8.0 0.6 15.5 10.7 6.2 2.8 16.2 0.0 0.0 33.3 0.2 12.2 0.0 8.1 0.2 8.1 1.9 6.2 1.8 29.5 1.3 36.2 4.1 3.6 23.4 5.7 3.8 3.5 1.4 91.6 10.9 0.0 1.0 6.0 8.2 5.9 3.8 0.7 1.8 6.1 0.0 1.9 1.4 0.1 0.0 0.5 0.0 20.8 7.7 7.5 0.1 8.3 11.8 1.5 36.1 0.1 6.6 4.1 3.3 0.6 0.2 19.5 1.4 23.7 0.4 13.1 11.6 8.9 C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 78.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA044977: AB_10961918, HPA055362: AB_2682794" "unprognostic (4.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.16e-2)" "unprognostic (2.20e-2)" "unprognostic (1.47e-3)" "unprognostic (5.51e-2)" "unprognostic (3.26e-3)" "unprognostic (1.16e-1)" "unprognostic (4.77e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (3.42e-2)" "unprognostic (2.91e-2)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" 20.2 19.7 23.2 10.2 23.3 10.0 22.4 23.8 29.5 13.0 21.3 12.3 6.9 17.1 43.4 16.2 20.5 12.6 16.1 22.2 23.5 19.9 14.1 9.9 15.2 24.3 23.2 17.8 15.7 20.6 10.7 11.3 24.4 16.0 11.7 9.4 16.0 15.4 10.3 20.6 7.6 16.7 24.2 10.9 11.3 19.3 23.0 13.5 20.5 14.5 14.0 13.9 10.9 26.6 17.0 15.7 22.4 14.3 31.7 38.3 12.8 23.4 16.7 15.0 16.3 10.1 11.3 20.7 40.6 24.7 17.4 7.8 10.1 14.9 15.0 17.7 33.5 39.1 11.7 13.5 21.8 15.0 24.6 20.4 25.3 21.3 13.8 19.3 21.7 15.7 12.6 19.6 22.5 25.7 15.7 28.5 12.4 13.3 12.4 9.6 4.7 29.1 33.9 18.0 14.8 16.7 17.0 24.1 33.7 21.0 13.2 52.5 20.3 17.4 13.5 14.6 12.7 12.8 22.5 22.1 17.5 11.1 20.0 29.1 20.9 21.9 19.9 20.2 18.0 20.0 15.2 18.3 21.3 14.7 13.8 19.3 37.2 32.5 12.7 20.1 16.8 11.9 23.2 23.3 23.8 29.5 22.2 23.5 24.3 23.2 24.4 24.2 23.0 26.6 30.3 6.4 11.4 22.5 11.1 25.0 17.2 47.7 17.1 3.3 18.5 19.7 18.5 12.8 24.4 14.7 0.0 26.4 15.2 7.1 78.2 14.7 11.7 27.6 15.4 20.4 10.9 16.4 12.4 17.8 32.4 20.7 9.7 19.7 22.2 8.4 15.0 11.6 26.7 1.7 8.6 11.2 22.4 15.0 23.4 7.7 19.3 13.8 44.4 12.2 20.6 19.8 26.8 14.6 25.2 14.0 9.2 17.0 8.9 11.8 12.2 47.0 42.8 4.6 6.6 13.8 18.8 38.8 22.4 18.8 35.7 20.7 15.3 11.4 10.0 13.0 DBI "ACBD1, ACBP" ENSG00000155368 "Diazepam binding inhibitor, acyl-CoA binding protein" P07108 2 119366921-119372560 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 2215.1;Proximal tubular cells: 2834.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 2479.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051428 Approved NA NA 9100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "HPA051428: AB_2681482" "unprognostic (1.24e-1)" "prognostic favorable (5.77e-5)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (1.92e-2)" "unprognostic (7.28e-3)" "unprognostic (1.70e-3)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (1.45e-1)" 358.3 153.9 486.0 158.7 470.8 121.9 717.3 495.6 726.7 218.6 452.3 322.8 312.8 73.5 653.7 667.7 85.8 129.7 515.4 493.0 498.5 536.2 971.1 236.0 182.9 499.4 495.1 86.0 143.8 866.9 76.9 116.3 510.0 451.5 297.3 116.3 369.9 215.1 273.0 451.0 229.6 97.2 512.7 115.5 185.1 201.3 487.6 173.3 133.7 460.5 324.5 136.5 327.7 516.4 543.0 276.9 557.1 257.2 1339.7 1131.9 350.7 281.3 708.7 387.0 746.1 580.6 427.8 747.3 312.1 440.6 938.5 277.9 397.0 588.3 345.9 498.2 262.1 641.4 279.9 775.8 335.6 206.1 2479.2 648.2 376.5 596.2 222.1 255.4 464.3 358.8 77.0 679.2 558.8 559.1 436.5 585.9 370.2 349.7 429.7 157.4 541.4 658.5 948.1 816.5 263.2 210.1 235.3 548.5 634.9 388.8 338.0 952.8 332.5 259.3 329.8 288.8 346.3 220.9 170.5 610.0 365.7 364.8 315.3 1180.7 439.9 1077.9 472.9 489.1 347.3 461.4 367.8 465.2 748.8 505.3 279.1 419.2 285.8 450.7 402.5 791.0 615.7 792.2 486.0 470.8 495.6 726.7 493.0 498.5 499.4 495.1 510.0 512.7 487.6 516.4 505.2 150.6 613.0 46.0 256.7 289.2 249.4 724.2 190.1 37.9 806.5 1025.9 1079.6 663.4 390.0 310.8 14.6 796.5 395.6 737.5 1197.4 466.9 844.4 154.8 194.7 206.2 371.3 108.8 5.2 670.3 643.2 258.2 243.1 185.6 433.4 219.4 167.8 2215.1 1069.4 30.3 3.9 495.0 524.9 305.0 785.7 325.7 152.2 476.1 1058.3 15.0 871.5 928.6 552.0 33.2 25.0 372.7 612.0 127.5 192.0 355.0 753.6 2834.8 340.5 59.1 151.2 267.2 289.9 462.0 30.1 972.6 684.9 516.3 260.8 456.0 673.2 361.0 TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 101.1;liver: 100.0;parathyroid gland: 124.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.9;Hepatocytes: 184.5;Muller glia cells: 146.8;Proximal enterocytes: 575.7;Proximal tubular cells: 188.1" "Cancer enhanced" "Detected in all" "renal cancer: 57.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "EFO-21: 26.9;Hep G2: 74.7;RPTEC TERT1: 60.0" "Low region specificity" "Detected in all" HPA053794 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA053794: AB_2682265" "unprognostic (2.54e-2)" "unprognostic (3.10e-2)" "unprognostic (1.01e-1)" "unprognostic (4.59e-3)" "unprognostic (2.56e-1)" "unprognostic (9.60e-2)" "unprognostic (5.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.36e-1)" "unprognostic (2.83e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-2)" "unprognostic (2.99e-1)" "unprognostic (2.61e-2)" 53.1 11.1 2.1 6.6 2.0 0.7 25.6 1.8 3.6 21.9 2.5 37.3 53.5 6.4 4.8 6.8 3.4 23.2 4.8 1.5 1.8 101.1 100.0 15.4 10.2 2.5 2.1 12.7 13.3 124.7 1.0 14.9 2.3 3.9 19.0 23.6 7.0 7.6 2.4 10.5 76.1 4.8 2.5 25.7 18.1 5.1 3.7 3.0 31.1 4.2 4.9 7.0 5.6 3.2 0.0 7.3 0.7 0.3 4.3 0.4 1.0 0.2 0.1 0.0 0.1 11.4 6.4 0.0 26.9 3.4 0.6 1.7 3.0 0.0 0.0 0.0 2.9 1.0 4.0 74.7 5.9 0.0 0.1 9.7 0.0 0.0 0.0 0.2 5.9 0.0 0.2 10.9 0.0 0.7 0.0 0.8 5.4 0.1 0.2 0.0 0.1 9.9 60.0 4.9 0.9 0.4 0.3 2.9 0.0 5.0 1.2 1.7 3.8 0.0 10.4 1.8 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.1 2.0 1.8 3.6 1.5 1.8 2.5 2.1 2.3 2.5 3.7 3.2 12.2 25.6 9.6 0.0 3.2 2.0 0.3 11.1 0.0 2.4 1.8 1.5 2.1 82.9 13.6 18.4 0.0 64.9 0.1 179.9 50.9 36.1 0.3 7.7 98.8 15.1 9.1 5.3 0.0 52.3 3.8 17.9 11.7 10.3 1.3 16.4 61.8 184.5 64.6 6.7 0.0 22.0 14.2 65.5 5.0 1.9 49.7 19.5 1.8 0.0 0.6 146.8 0.0 0.0 0.6 15.3 68.1 3.8 0.0 0.1 575.7 188.1 7.6 17.4 0.0 0.9 14.8 0.0 0.8 1.0 2.8 104.1 2.4 45.3 23.3 2.3 SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 26.6;pancreas: 68.2" "Group enriched" "Detected in some" 6 "Alveolar cells type 2: 54.4;Ductal cells: 92.0;Exocrine glandular cells: 93.8;Pancreatic endocrine cells: 41.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "basophil: 1.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.5" "Cell line enriched" "Detected in single" 5 "Karpas-707: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA007269 Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 2: Karpas-707 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" 0.3 0.4 0.3 0.2 0.3 0.3 0.0 0.6 1.2 0.0 0.3 0.1 26.6 0.2 0.2 0.3 0.4 0.4 0.3 0.4 0.4 12.5 0.4 8.6 0.1 0.3 0.2 0.4 68.2 0.1 0.2 0.1 0.4 0.0 0.0 2.4 0.0 0.0 0.2 0.2 3.8 0.0 0.2 0.3 4.5 0.5 0.6 0.1 0.9 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.6 1.2 0.4 0.4 0.3 0.2 0.4 0.2 0.6 0.4 0.0 0.0 54.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.4 0.0 1.8 5.5 0.0 0.0 0.0 0.1 11.7 92.0 4.5 0.0 0.2 0.1 2.4 0.0 3.0 93.8 0.0 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.7 5.0 4.1 0.1 0.0 0.0 0.0 1.7 0.0 0.2 0.0 1.0 1.6 0.3 0.0 0.0 0.7 41.9 0.0 0.0 0.0 0.1 0.1 0.5 0.0 1.9 0.0 0.0 0.6 0.3 0.9 0.0 0.0 0.3 0.4 0.0 0.1 0.0 CFAP221 "FAP221, PCDP1" ENSG00000163075 "Cilia and flagella associated protein 221" Q4G0U5 2 119544432-119662251 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 29.6;testis: 25.4" "Cell type enhanced" "Detected in many" "Early spermatids: 182.9;Endometrial ciliated cells: 96.5;Excitatory neurons: 93.3;Late spermatids: 292.7;Respiratory ciliated cells: 97.7;Spermatocytes: 64.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.8;HeLa: 2.3;RPTEC TERT1: 5.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.98e-1)" "unprognostic (1.70e-1)" "unprognostic (5.27e-2)" "unprognostic (7.62e-3)" "unprognostic (6.26e-4)" "unprognostic (3.52e-2)" "unprognostic (2.58e-1)" "unprognostic (7.71e-3)" "unprognostic (1.72e-1)" "unprognostic (3.75e-2)" "unprognostic (1.16e-1)" "unprognostic (2.90e-3)" "unprognostic (2.21e-3)" "unprognostic (8.96e-3)" "unprognostic (3.06e-2)" "unprognostic (7.03e-3)" "unprognostic (2.19e-1)" 0.3 1.6 0.5 0.2 0.9 1.0 0.1 0.0 5.9 1.2 12.0 0.2 8.6 1.1 1.8 0.2 29.6 2.0 0.6 1.9 0.7 13.1 1.3 7.8 0.4 5.7 6.8 0.5 9.9 1.8 3.2 0.6 3.2 0.5 0.2 5.2 0.2 0.6 0.2 1.0 1.0 0.1 2.9 0.4 2.2 25.4 1.4 0.1 2.5 0.2 0.3 0.2 0.2 1.5 0.1 0.3 1.1 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 1.8 0.2 0.2 1.1 0.0 0.7 0.1 0.0 0.1 0.1 0.2 1.0 0.1 2.3 0.3 0.3 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.6 0.0 0.3 0.4 0.7 0.2 0.2 0.1 0.4 0.0 0.1 5.4 0.5 0.6 0.7 0.1 0.1 0.0 0.4 1.4 0.4 0.3 0.2 0.5 0.2 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.3 0.2 0.2 0.7 0.3 0.2 0.2 0.1 0.0 0.5 0.9 0.0 5.9 1.9 0.7 5.7 6.8 3.2 2.9 1.4 1.5 0.0 0.0 35.3 24.8 0.0 0.0 0.1 0.0 0.0 3.4 0.4 0.0 2.4 10.0 13.0 7.3 29.2 0.1 0.0 0.0 27.4 19.6 182.9 96.5 1.7 0.4 0.0 0.0 93.3 18.6 0.0 0.9 0.0 3.0 0.0 0.5 0.0 2.4 0.1 0.0 36.7 0.1 0.0 0.0 0.0 292.7 2.8 0.7 0.0 1.0 0.6 3.7 0.0 1.0 2.5 8.4 0.0 2.2 0.0 0.2 0.1 8.7 97.7 31.0 0.0 1.2 1.0 64.7 15.2 0.0 0.0 0.0 0.4 1.4 0.4 0.0 TMEM177 MGC10993 ENSG00000144120 "Transmembrane protein 177" Q53S58 2 119679167-119686507 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 66.5;Proximal tubular cells: 47.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036689, HPA053816" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli fibrillar center" "HPA036689: AB_2675253, HPA053816: AB_2682272" "unprognostic (1.24e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-2)" "unprognostic (2.31e-2)" "unprognostic (9.81e-3)" "unprognostic (2.05e-3)" "unprognostic (3.17e-2)" "unprognostic (8.05e-2)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-1)" "unprognostic (4.90e-1)" "unprognostic (6.73e-2)" "unprognostic (5.29e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-1)" "unprognostic (1.02e-1)" 3.2 8.0 6.6 4.8 7.1 1.0 6.8 7.4 7.7 5.3 3.3 10.9 16.1 6.6 9.0 5.7 10.6 3.9 8.2 6.8 4.6 13.4 25.7 3.3 5.1 4.2 6.2 7.9 5.5 8.2 12.5 3.2 4.5 5.9 9.1 7.2 6.9 5.9 12.2 6.7 13.7 5.2 3.9 4.0 6.3 7.7 6.6 4.7 5.6 7.0 5.2 5.2 4.9 6.6 22.9 19.9 17.2 16.7 4.6 4.5 8.9 8.4 10.4 24.3 18.3 50.4 12.6 37.9 20.1 7.4 19.9 13.7 27.9 28.7 14.0 18.0 51.4 19.5 11.8 56.7 10.1 12.5 13.9 12.4 20.1 19.2 12.5 9.3 15.7 22.3 30.7 4.9 13.3 19.0 21.8 24.3 44.0 16.7 29.2 19.6 16.8 22.4 24.4 11.8 33.8 19.3 10.9 23.2 26.9 15.9 17.7 21.1 12.8 12.0 28.7 9.2 16.7 4.9 3.8 23.3 4.5 15.2 22.0 0.0 2.6 2.6 8.2 2.1 8.5 6.6 6.9 8.4 4.9 8.7 16.2 10.3 0.8 7.2 1.4 5.8 7.9 5.5 6.6 7.1 7.4 7.7 6.8 4.6 4.2 6.2 4.5 3.9 6.6 6.6 2.6 3.2 0.0 3.3 3.6 2.9 12.1 13.9 1.8 13.3 8.2 9.7 13.0 11.5 10.7 5.5 14.6 11.9 2.1 8.9 66.5 16.0 2.2 4.0 6.8 5.0 2.4 3.4 4.1 14.3 9.7 5.4 5.6 2.8 0.0 10.1 1.4 30.5 6.3 11.8 4.1 7.2 8.2 1.2 1.1 2.1 7.5 1.5 14.2 0.0 4.7 9.4 5.2 5.5 2.0 12.3 6.5 12.4 3.4 9.2 22.8 47.2 5.4 21.8 0.0 2.6 6.1 6.5 6.6 5.1 2.0 2.1 4.1 21.5 14.1 4.5 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase non-receptor type 4" P29074 2 119759922-119984899 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 224.3;Horizontal cells: 161.5;Inhibitory neurons: 187.5;NK-cells: 247.2;Oligodendrocyte precursor cells: 200.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 37.3" "Group enriched" "Detected in many" 4 "gdT-cell: 35.0;MAIT T-cell: 28.1;memory CD4 T-cell: 16.9;memory CD8 T-cell: 27.9;naive CD8 T-cell: 19.2;NK-cell: 24.4;T-reg: 11.0" "Group enriched" "Detected in many" 16 "NK-cells: 24.4;T-cells: 35.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favorable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 4.5 3.8 5.9 3.6 5.0 5.1 4.7 37.3 10.1 5.7 0.0 3.4 5.1 4.1 4.2 4.1 5.5 3.7 5.7 5.2 2.7 7.4 4.2 5.2 5.4 0.1 9.6 5.2 2.8 6.3 3.5 2.5 1.4 3.5 2.4 12.1 4.1 2.5 8.0 3.0 2.8 2.8 0.0 5.9 5.7 4.9 12.6 8.1 14.0 12.8 4.2 3.2 2.6 5.9 7.4 4.3 5.0 7.3 4.8 5.0 9.1 3.2 9.3 1.8 4.9 6.2 10.9 4.1 7.6 3.5 5.2 5.3 4.4 5.1 4.8 12.6 3.6 3.7 3.5 6.1 3.2 3.9 2.6 4.5 9.6 8.5 3.7 6.0 8.2 4.8 5.7 4.8 5.0 5.0 5.2 4.4 7.3 4.0 6.9 3.4 9.6 6.9 6.7 10.0 6.8 8.5 4.2 5.8 4.0 4.0 2.8 2.4 10.7 0.0 6.1 1.9 4.0 8.9 13.7 6.6 4.7 0.1 3.0 0.3 0.2 1.8 35.0 0.5 28.1 0.6 16.9 27.9 0.5 0.6 5.2 19.2 0.6 24.4 0.7 0.3 11.0 10.4 5.9 5.0 37.3 10.1 5.2 2.7 0.1 9.6 1.4 0.0 12.6 5.9 20.5 3.2 14.6 128.9 24.4 8.2 15.5 8.5 27.3 55.7 13.9 11.2 17.9 10.0 8.3 16.5 104.3 10.5 95.5 7.3 7.9 8.0 5.4 18.2 15.7 15.0 9.1 35.4 224.3 7.3 11.8 11.3 16.8 15.8 11.4 47.9 15.0 11.0 4.0 161.5 187.5 9.9 12.2 8.6 7.6 8.8 17.4 9.0 8.8 38.4 11.8 24.9 247.2 200.6 113.6 6.3 9.6 14.3 30.1 12.7 10.6 13.6 8.8 79.8 0.0 25.5 9.0 31.4 26.4 12.8 6.7 3.7 79.4 23.3 11.5 9.5 EPB41L5 "BE37, FLJ12957, KIAA1548, LULU, LULU1, YMO1, YRT" ENSG00000115109 "Erythrocyte membrane protein band 4.1 like 5" Q9HCM4 2 120013077-120179119 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 55.5;MCF7: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037563, HPA037564" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA037563: AB_2675546, HPA037564: AB_2675547" "unprognostic (1.27e-2)" "unprognostic (2.15e-1)" "unprognostic (2.56e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-2)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (5.93e-2)" "unprognostic (8.76e-2)" "unprognostic (2.20e-2)" "unprognostic (9.51e-2)" "prognostic favorable (2.28e-6)" "unprognostic (1.99e-1)" "unprognostic (3.88e-1)" "unprognostic (9.59e-2)" "unprognostic (2.61e-1)" 5.7 6.0 9.0 3.0 7.3 1.0 15.7 43.4 10.6 7.2 4.5 9.9 14.0 7.5 5.8 8.8 12.8 7.4 6.3 7.1 11.1 32.7 56.8 29.9 2.5 8.9 11.1 11.6 26.2 25.1 8.2 9.8 9.0 12.4 8.8 27.8 15.3 6.1 10.1 8.3 11.7 6.5 8.7 2.5 9.1 30.5 12.4 3.6 32.9 8.9 6.6 6.1 8.4 8.1 18.0 6.1 23.8 18.5 16.4 11.8 20.8 3.8 3.7 7.8 7.0 55.5 11.7 0.3 12.9 4.8 9.7 12.1 32.4 14.9 11.5 3.6 10.1 5.2 2.8 31.1 19.1 2.3 5.3 10.6 27.6 14.6 10.4 6.7 22.1 10.4 12.4 1.3 15.6 83.4 4.3 7.9 21.5 8.3 5.6 0.0 7.1 5.0 24.2 17.1 12.3 23.5 16.5 29.0 8.2 32.5 14.0 4.3 18.4 0.7 11.2 12.3 3.9 1.9 3.5 9.2 2.0 0.1 4.5 0.1 0.5 0.6 0.4 0.1 0.1 1.7 0.4 0.4 0.1 1.3 1.1 0.8 0.7 0.6 0.3 0.0 0.2 0.4 9.0 7.3 43.4 10.6 7.1 11.1 8.9 11.1 9.0 8.7 12.4 8.1 6.0 218.0 41.9 61.0 11.1 24.5 28.9 9.7 21.6 33.9 28.0 14.1 13.2 24.3 22.5 33.1 25.0 14.9 4.3 20.6 21.5 18.8 38.0 25.8 12.6 6.8 15.5 5.7 68.4 22.3 12.1 13.1 56.1 45.8 0.0 12.0 17.9 54.2 3.2 8.4 79.8 12.7 22.4 2.1 6.8 20.6 9.0 2.8 14.2 26.2 1.1 15.8 0.0 89.5 25.9 23.2 21.7 9.4 5.9 29.1 20.9 29.0 17.5 35.7 19.7 11.7 9.8 43.5 48.6 18.3 21.7 26.4 6.2 5.7 12.9 39.4 TMEM185B "FAM11B, FLJ20979" ENSG00000226479 "Transmembrane protein 185B" Q9H7F4 2 120217479-120223400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048295, HPA071744" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Endoplasmic reticulum" "HPA048295: AB_2680345, HPA071744: AB_2686441" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.44e-4)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.35e-2)" "unprognostic (1.55e-2)" "prognostic unfavorable (5.71e-7)" "unprognostic (3.09e-3)" "unprognostic (1.65e-1)" "unprognostic (9.01e-2)" "unprognostic (1.96e-2)" "unprognostic (8.28e-2)" "unprognostic (6.03e-3)" "unprognostic (1.72e-1)" "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" 11.8 7.9 7.6 7.6 8.8 5.7 9.8 8.3 7.4 7.4 7.7 8.5 6.1 10.4 5.2 9.9 9.6 6.5 11.9 7.3 7.8 9.3 6.8 8.7 6.9 8.7 8.6 5.5 9.0 25.9 6.3 7.3 8.5 9.3 5.9 4.5 9.9 7.0 10.8 7.9 8.0 9.1 8.5 7.2 8.1 13.1 8.3 7.4 10.2 7.8 7.8 9.4 8.1 9.4 29.5 11.2 9.0 18.8 20.2 24.9 16.7 23.1 21.1 19.3 16.5 34.8 27.7 0.0 16.7 20.9 22.1 18.1 8.8 17.2 24.2 13.5 15.4 13.5 9.7 7.3 22.7 0.0 26.3 20.7 24.9 20.8 24.7 18.1 15.7 14.7 13.1 14.9 17.3 23.2 13.9 19.6 13.0 13.1 23.7 9.7 0.0 9.1 17.9 22.0 13.5 12.8 19.1 27.5 18.2 10.2 9.5 21.4 20.2 10.2 22.7 20.9 8.6 10.1 15.5 12.8 12.4 15.2 27.9 0.1 0.6 0.9 0.9 0.9 1.0 0.3 0.7 0.5 0.6 0.4 0.7 0.7 1.5 1.4 0.7 0.5 0.8 0.3 7.6 8.8 8.3 7.4 7.3 7.8 8.7 8.6 8.5 8.5 8.3 9.4 12.2 16.0 2.6 4.9 9.4 8.4 36.0 7.3 14.8 2.7 8.2 5.7 8.6 5.7 4.3 7.3 6.2 9.4 4.7 4.6 1.9 18.0 12.6 4.1 5.7 11.1 1.2 3.4 2.0 12.3 29.3 12.1 12.2 7.4 7.0 5.4 7.5 4.5 15.4 1.7 1.8 4.5 2.0 7.2 4.7 6.1 4.7 8.4 7.2 3.7 5.4 7.5 5.2 5.5 6.1 13.4 6.7 2.2 6.9 16.2 5.0 3.9 6.0 3.8 0.0 17.1 8.8 18.5 9.3 10.4 4.4 14.5 7.9 4.1 4.6 14.2 RALB ENSG00000144118 "RAS like proto-oncogene B" P11234 2 120240064-120294710 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Cell division" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "parathyroid gland: 335.7" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 138.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 378.4" "Group enriched" "Detected in all" 4 "granulocytes: 378.4;monocytes: 176.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026010, HPA065232" Enhanced NA NA 440000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB026010: , HPA065232: AB_2685440" "unprognostic (5.16e-2)" "unprognostic (9.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.38e-2)" "unprognostic (3.89e-2)" "unprognostic (5.92e-3)" "unprognostic (1.77e-2)" "unprognostic (4.15e-2)" "unprognostic (4.91e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.67e-4)" "unprognostic (2.29e-2)" "unprognostic (8.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.12e-2)" "unprognostic (1.38e-1)" "unprognostic (2.72e-2)" 53.8 35.9 30.6 57.2 30.8 60.0 39.9 32.8 38.7 44.3 33.1 59.2 50.5 37.5 15.8 73.3 45.7 44.8 51.0 32.3 37.7 56.5 34.2 50.7 35.8 30.8 33.6 28.7 25.6 335.7 16.6 63.1 30.6 51.0 51.8 25.8 36.2 31.7 30.1 25.7 44.8 46.5 31.3 54.2 39.3 29.9 37.9 27.5 30.8 43.9 35.0 51.0 49.1 32.8 179.8 47.7 46.8 29.5 71.2 115.5 66.7 121.4 105.8 93.3 70.5 99.4 118.0 7.1 63.9 131.6 88.2 64.1 22.5 93.1 85.7 293.3 25.8 84.4 36.3 71.3 46.0 45.1 144.9 60.3 99.0 97.2 74.0 77.1 272.9 6.3 66.5 28.1 108.2 91.9 5.9 100.0 31.7 71.6 101.9 1.2 59.3 38.1 97.5 45.6 13.3 32.1 50.4 137.9 85.1 39.3 43.3 66.3 168.4 91.1 69.8 93.9 48.8 16.2 9.1 12.8 72.7 57.5 95.6 101.8 80.9 230.5 19.0 117.7 18.5 45.0 18.0 19.0 65.4 59.6 11.9 13.7 378.4 25.5 176.1 6.9 24.6 59.5 30.6 30.8 32.8 38.7 32.3 37.7 30.8 33.6 30.6 31.3 37.9 32.8 69.3 9.6 27.0 6.5 23.8 19.4 30.1 22.4 7.4 4.1 23.2 7.9 55.8 18.6 21.9 11.0 12.5 6.0 11.8 95.3 66.5 84.9 18.8 28.4 22.8 77.8 18.6 8.4 12.9 55.0 128.5 32.7 17.9 26.7 106.1 90.6 78.5 9.8 53.6 13.5 9.7 19.1 18.3 54.3 59.4 23.0 19.9 66.7 35.6 16.9 62.6 26.3 21.6 10.1 5.4 138.1 62.1 31.2 6.7 28.5 44.6 104.4 46.3 7.5 19.7 18.3 33.4 13.1 16.2 16.4 18.9 36.7 19.5 12.9 31.3 32.2 INHBB ENSG00000163083 "Inhibin subunit beta B" P09529 2 120346136-120351803 "Cancer-related genes, Predicted secreted proteins" "Growth factor, Hormone" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.5;breast: 43.3" "Group enriched" "Detected in many" 7 "Adipocytes: 200.5;Granulosa cells: 653.3" "Cancer enhanced" "Detected in all" "thyroid cancer: 44.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 47.6;ASC diff: 63.1;BJ hTERT+ SV40 Large T+ RasG12V: 38.5;MCF7: 58.4;PC-3: 91.7;SK-BR-3: 163.4;T-47d: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 130000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.80e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.26e-2)" "unprognostic (4.26e-2)" "unprognostic (3.61e-3)" "unprognostic (2.13e-2)" "unprognostic (5.52e-2)" "unprognostic (6.99e-2)" "unprognostic (3.59e-1)" "unprognostic (1.59e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.02e-4)" "unprognostic (1.57e-3)" "unprognostic (4.14e-1)" "prognostic favorable (1.02e-4)" "unprognostic (1.76e-2)" 52.5 3.7 5.6 0.9 5.5 0.2 43.3 8.0 4.0 6.9 3.4 3.4 1.3 7.4 2.6 2.5 6.2 2.5 6.4 3.9 4.8 4.3 20.2 4.4 1.1 9.7 7.4 2.5 4.2 6.3 8.0 1.2 6.0 8.2 0.3 1.0 16.4 0.8 10.4 17.1 2.4 2.2 6.2 0.5 3.6 17.1 7.9 0.4 20.9 2.4 0.7 8.2 6.4 4.2 24.5 47.6 0.2 0.0 63.1 4.9 0.0 3.3 3.8 20.7 38.5 1.0 0.0 0.0 8.3 1.2 0.1 0.1 3.7 0.0 28.9 0.1 0.8 0.0 0.0 1.2 1.0 0.0 0.1 2.6 3.5 0.7 0.0 0.3 0.4 0.0 0.0 0.0 0.1 58.4 0.0 0.1 0.0 4.7 91.7 0.0 0.0 1.2 5.6 0.0 5.4 0.0 0.2 163.4 0.0 0.0 39.2 0.5 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.6 5.5 8.0 4.0 3.9 4.8 9.7 7.4 6.0 6.2 7.9 4.2 200.5 3.2 2.2 8.1 0.2 4.0 2.2 5.5 0.0 0.1 53.7 24.4 0.7 8.6 9.2 1.8 25.0 0.1 0.7 0.1 0.0 0.4 0.6 9.2 1.6 24.3 0.0 2.7 0.1 0.0 0.2 9.8 0.0 12.5 0.0 653.3 24.7 19.4 0.1 0.0 1.3 0.0 8.2 1.3 6.6 3.6 11.8 1.3 1.8 1.0 0.0 0.2 0.0 2.5 0.0 0.2 0.0 6.8 0.3 8.9 0.0 0.0 30.0 0.6 0.0 37.3 3.1 0.8 6.0 0.6 3.0 0.1 0.6 0.2 0.0 3.2 GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 10.9" "Cell type enhanced" "Detected in some" "Astrocytes: 39.5;Fibroblasts: 10.4;Leydig cells: 25.1;Peritubular cells: 30.9;Skeletal myocytes: 16.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 20.1;hTEC/SVTERT24-B: 13.1;U-2 OS: 17.9;WM-115: 18.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB008558, HPA074275" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "CAB008558: AB_2111910, HPA074275: AB_2686677" "unprognostic (6.76e-2)" "unprognostic (2.51e-1)" "unprognostic (1.05e-1)" "unprognostic (9.83e-3)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (9.43e-2)" "unprognostic (1.65e-2)" "unprognostic (2.19e-3)" "unprognostic (2.58e-1)" "unprognostic (9.23e-3)" "unprognostic (1.81e-2)" "unprognostic (4.49e-10)" "unprognostic (1.13e-1)" "unprognostic (8.88e-2)" "unprognostic (2.32e-2)" "unprognostic (1.42e-3)" 1.6 1.0 1.9 0.9 2.2 0.0 1.4 1.4 1.3 4.3 0.6 3.4 0.4 4.7 1.2 0.8 2.8 2.1 2.3 1.1 1.9 1.4 0.4 2.0 0.3 2.1 2.1 10.9 0.3 0.1 1.8 0.8 1.8 2.9 0.6 0.0 1.4 1.1 0.9 2.7 1.6 1.9 1.6 0.8 1.6 2.4 1.8 1.3 1.0 0.4 0.3 3.1 2.4 0.9 0.0 10.3 20.1 5.5 3.2 4.0 0.0 5.8 1.8 2.4 2.4 0.0 0.5 0.0 0.9 5.2 0.9 0.3 4.3 0.2 1.9 0.0 2.1 0.4 6.1 0.2 3.8 0.0 1.2 2.3 0.0 13.1 0.0 2.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 10.6 1.6 4.3 0.1 2.2 3.5 0.0 0.0 2.0 2.1 3.8 0.0 0.2 4.3 0.1 0.0 5.1 0.0 17.9 2.5 0.0 0.0 0.1 0.0 7.4 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 2.2 1.4 1.3 1.1 1.9 2.1 2.1 1.8 1.6 1.8 0.9 0.3 0.0 0.0 39.5 0.0 2.0 0.1 0.5 0.6 0.0 0.1 0.9 1.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.1 0.3 6.1 0.5 0.0 0.0 0.7 0.2 0.1 10.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 1.5 2.1 25.1 0.1 0.0 2.8 0.0 0.0 1.0 3.0 0.3 1.0 0.0 30.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 16.0 3.4 0.1 3.6 0.1 1.7 0.0 0.0 7.9 0.0 0.1 TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 49.1;salivary gland: 97.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 79.1;Distal enterocytes: 117.9;Glandular and luminal cells: 83.0;Ionocytes: 262.4" "Cancer enhanced" "Detected in many" "testis cancer: 21.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 18.2;HEL: 15.7;hTCEpi: 17.3;RPTEC TERT1: 42.4;RT4: 31.8;SCLC-21H: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center" Mitochondria "HPA029708: AB_10602479" "unprognostic (8.85e-3)" "unprognostic (4.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.02e-2)" "unprognostic (1.48e-1)" "unprognostic (3.91e-2)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (3.25e-2)" "unprognostic (2.72e-3)" "unprognostic (1.20e-3)" "unprognostic (5.76e-2)" "prognostic favorable (7.72e-6)" "unprognostic (1.05e-1)" "unprognostic (2.39e-1)" "unprognostic (6.67e-3)" "unprognostic (2.01e-1)" 1.9 0.3 0.9 1.7 1.6 0.2 28.7 1.7 1.1 18.1 19.0 19.0 0.6 0.5 8.3 13.3 3.5 2.9 0.2 1.7 0.9 49.1 0.2 5.6 0.2 1.6 2.1 0.1 6.4 2.6 0.8 7.4 1.1 13.6 22.6 0.0 97.5 2.0 2.6 31.9 3.2 0.6 0.7 1.8 16.3 1.1 1.9 0.2 37.6 0.1 1.2 1.8 10.9 0.7 0.0 1.6 0.0 0.1 0.0 0.0 18.2 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.7 0.0 0.7 0.4 4.4 4.5 0.0 0.0 3.2 15.7 0.0 0.0 0.0 0.0 0.6 0.0 17.3 0.0 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.9 0.1 0.0 0.5 2.1 42.4 31.8 13.3 0.1 1.7 0.1 0.0 6.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.7 1.1 1.7 0.9 1.6 2.1 1.1 0.7 1.9 0.7 0.1 6.4 28.8 3.9 0.3 1.7 38.0 10.3 28.5 0.0 22.1 11.6 2.6 17.2 35.4 79.1 0.0 32.2 0.9 117.9 31.3 2.7 0.1 43.5 5.8 1.0 10.2 0.0 0.2 1.5 2.3 0.8 58.6 83.0 0.0 1.2 0.0 0.4 4.9 0.0 0.3 31.2 262.4 4.6 0.8 0.5 0.3 5.5 7.2 9.4 0.2 0.5 0.0 0.0 0.1 7.4 28.0 0.0 2.1 36.3 0.3 27.7 11.9 0.0 0.0 1.9 1.1 0.1 1.5 41.0 3.3 20.2 1.1 9.5 44.3 40.7 CLASP1 "KIAA0622, MAST1" ENSG00000074054 "Cytoplasmic linker associated protein 1" Q7Z460 2 121337776-121649476 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 197.9;Excitatory neurons: 248.4;Inhibitory neurons: 212.5;Oligodendrocyte precursor cells: 233.2;Oligodendrocytes: 283.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065219 Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA065219: AB_2685436" "unprognostic (6.21e-2)" "unprognostic (6.26e-2)" "unprognostic (2.45e-1)" "unprognostic (2.06e-3)" "unprognostic (4.06e-2)" "unprognostic (3.94e-1)" "unprognostic (7.87e-2)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (6.50e-4)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (5.41e-2)" "unprognostic (1.14e-1)" 13.2 12.6 17.7 8.2 18.7 17.2 11.9 27.9 21.6 11.9 13.9 13.4 6.3 11.9 11.7 11.2 11.3 8.9 20.4 19.7 22.3 10.7 11.6 9.8 10.3 17.1 14.9 15.9 10.1 11.2 11.5 9.0 17.0 11.1 6.9 43.8 9.2 11.4 42.6 15.4 9.7 10.7 11.0 11.4 9.5 18.8 19.1 13.2 13.3 27.5 9.6 11.7 11.9 18.0 15.6 14.1 36.2 21.4 26.0 25.6 11.0 16.9 20.6 16.7 19.4 22.0 10.1 24.3 13.1 18.1 17.1 13.1 26.1 32.2 20.4 30.4 9.6 45.1 18.3 24.9 21.0 20.9 21.7 23.7 24.5 22.7 54.1 18.3 18.9 14.4 29.2 26.9 24.6 13.9 23.8 20.4 21.7 5.8 14.1 30.7 18.3 17.6 19.2 21.9 21.0 26.9 19.6 10.1 17.5 22.3 6.4 14.9 21.3 21.7 21.5 12.6 12.1 15.7 16.5 24.1 17.2 18.9 33.8 1.7 0.8 0.9 1.9 0.8 1.5 0.8 1.0 1.1 0.8 0.8 1.1 1.1 0.9 5.7 1.1 1.0 0.9 0.9 17.7 18.7 27.9 21.6 19.7 22.3 17.1 14.9 17.0 11.0 19.1 18.0 21.8 22.4 12.8 197.9 12.1 10.7 10.0 14.0 22.2 35.0 12.7 10.4 43.6 11.5 13.1 12.9 45.9 6.6 27.1 7.3 5.9 11.8 31.4 19.6 14.7 17.5 9.0 20.6 248.4 6.0 4.4 13.8 9.7 22.6 14.5 22.1 42.1 21.9 7.7 62.2 212.5 6.2 14.2 14.1 6.9 47.6 28.6 12.0 8.8 131.2 12.9 29.4 46.4 233.2 283.4 11.9 7.4 56.8 21.9 8.1 5.6 7.9 17.6 57.0 6.6 20.6 15.2 14.3 23.4 16.3 11.8 3.7 17.6 10.3 6.6 9.6 NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: AB_2142390, CAB075728: AB_2665734, CAB075729: AB_2665735, HPA035735: AB_2674758, HPA035736: AB_2674759" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (3.49e-1)" "prognostic unfavorable (5.57e-4)" "unprognostic (1.21e-1)" "unprognostic (4.15e-3)" "prognostic unfavorable (2.92e-6)" "unprognostic (7.74e-3)" "unprognostic (4.63e-2)" "unprognostic (3.21e-2)" "unprognostic (6.02e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (5.01e-11)" "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" 29.3 24.8 18.1 31.9 18.6 31.5 37.3 18.7 21.8 25.4 17.9 24.8 25.1 28.5 21.9 34.6 27.5 25.1 22.9 19.3 18.7 25.7 34.1 17.9 47.2 18.5 17.8 36.5 32.6 17.9 16.7 25.6 18.4 24.6 25.6 23.0 17.9 17.8 38.3 34.5 20.1 24.8 19.1 22.3 22.5 21.8 18.3 32.9 25.2 18.3 42.4 43.3 24.5 20.1 118.4 37.6 68.8 68.3 57.9 80.6 90.2 90.6 75.2 105.0 113.2 105.9 55.0 152.4 111.4 66.9 93.1 72.9 149.4 116.4 153.4 101.3 85.7 155.0 44.5 92.9 82.6 141.1 81.7 80.6 126.7 137.4 184.4 48.7 75.9 60.3 174.5 73.9 90.5 58.2 109.5 140.9 175.3 132.4 122.5 102.5 80.7 191.2 92.1 72.4 88.1 91.8 56.6 105.1 200.7 62.2 52.0 123.1 45.7 72.8 123.5 85.6 129.3 87.5 150.6 182.1 55.7 143.9 101.5 41.8 54.2 28.8 59.2 65.3 83.4 73.6 72.3 68.6 72.1 74.8 84.5 79.4 4.0 81.5 62.5 64.0 68.9 75.1 18.1 18.6 18.7 21.8 19.3 18.7 18.5 17.8 18.4 19.1 18.3 20.1 51.1 44.8 25.9 8.1 56.3 98.4 128.9 87.0 81.4 25.8 51.2 88.8 21.5 24.3 62.2 14.7 12.5 74.9 62.7 18.9 46.9 64.2 23.7 43.8 126.9 47.7 28.1 41.8 8.2 45.2 90.6 68.7 32.6 39.9 54.5 47.9 26.0 33.2 54.4 13.5 7.2 41.3 42.7 34.5 32.8 8.0 57.5 39.0 23.2 10.3 59.1 48.0 54.6 13.0 8.0 51.5 28.4 45.1 33.3 107.0 18.4 58.4 41.9 45.8 39.5 72.7 54.3 81.1 83.9 79.3 101.4 48.8 52.5 97.7 60.5 125.2 TSN "BCLF-1, REHF-1, TRSLN" ENSG00000211460 Translin Q15631 2 121737103-121767853 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059561 Uncertain Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 280000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Endoplasmic reticulum" "HPA059561: AB_2684063" "unprognostic (3.15e-2)" "unprognostic (1.83e-1)" "unprognostic (3.53e-1)" "prognostic unfavorable (7.05e-4)" "unprognostic (7.13e-3)" "unprognostic (3.12e-2)" "prognostic unfavorable (3.06e-4)" "unprognostic (2.32e-2)" "unprognostic (7.58e-2)" "unprognostic (2.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.04e-2)" "unprognostic (3.42e-2)" "unprognostic (3.18e-1)" 16.2 16.9 20.9 13.5 21.9 47.8 25.4 22.7 28.4 17.4 18.9 23.3 16.9 15.8 17.9 16.6 14.2 13.2 19.5 21.0 23.6 24.4 22.9 14.3 19.1 21.3 22.4 16.7 18.4 21.7 13.1 10.8 22.3 14.5 18.8 16.6 14.9 17.2 31.6 19.3 14.6 14.2 21.4 14.7 15.0 26.2 22.0 24.1 17.2 31.0 18.2 15.6 12.8 23.8 56.2 24.8 38.4 34.1 35.0 27.8 21.1 45.6 43.2 50.3 48.4 71.1 32.3 81.7 51.9 45.4 30.1 27.0 55.0 46.6 69.8 43.2 44.3 48.0 33.0 68.3 40.0 69.3 32.5 24.2 51.3 56.3 38.7 23.0 43.2 40.0 72.9 39.4 47.4 30.5 38.2 77.5 46.6 32.8 47.2 67.6 43.1 59.3 63.7 36.0 48.9 30.6 31.4 46.6 61.2 29.2 29.3 54.1 30.8 36.2 56.4 22.9 45.1 33.8 97.0 85.4 40.3 46.8 45.6 27.6 29.8 28.6 22.5 27.9 26.9 27.4 23.4 19.8 27.4 21.0 26.5 22.9 9.3 26.9 24.3 20.1 25.6 28.8 20.9 21.9 22.7 28.4 21.0 23.6 21.3 22.4 22.3 21.4 22.0 23.8 34.7 32.1 24.4 15.0 37.5 39.1 34.4 49.1 23.3 32.1 38.2 27.6 34.7 42.9 36.9 42.3 22.9 34.9 34.3 22.3 43.0 64.4 80.0 24.9 29.7 42.7 19.9 34.7 19.8 60.0 33.3 32.5 15.8 23.9 40.0 36.0 58.5 44.4 35.2 16.8 19.8 27.7 57.0 35.6 34.9 19.8 36.4 29.8 67.6 15.0 45.4 88.7 44.3 29.1 33.5 45.4 22.2 31.2 25.4 34.7 24.4 58.7 33.0 29.5 26.3 39.9 81.8 152.8 96.6 36.7 43.9 28.5 36.8 38.5 37.9 28.8 CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124915287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 7.9" "Group enriched" "Detected in some" 49 "Excitatory neurons: 554.6;Inhibitory neurons: 906.4;Oligodendrocyte precursor cells: 760.0" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: AB_2686083, HPA069356: AB_2686127" "unprognostic (6.32e-3)" "unprognostic (6.38e-2)" "unprognostic (1.23e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-6)" "unprognostic (3.65e-3)" "unprognostic (5.32e-2)" "unprognostic (9.58e-2)" 0.0 0.5 2.4 0.0 0.6 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.3 5.1 0.1 0.0 0.0 0.0 6.8 6.3 0.0 0.1 0.0 0.0 0.0 7.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 7.9 4.3 5.1 6.8 6.3 7.3 0.0 7.2 0.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.1 0.0 0.0 554.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 906.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.4 0.0 1.0 0.0 760.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 TEX51 ENSG00000237524 "Testis expressed 51" A0A1B0GUA7 2 126898864-126902097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 183 "testis: 59.9" "Cell type enriched" "Detected in single" 11 "Proximal tubular cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BIN1 "AMPH2, AMPHL, SH3P9" ENSG00000136717 "Bridging integrator 1" O00499 2 127048027-127107288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 2105.3;tongue: 803.2" "Cell type enhanced" "Detected in all" "Hofbauer cells: 164.9;NK-cells: 176.1;Oligodendrocytes: 186.4;Proximal tubular cells: 255.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "gdT-cell: 186.6;MAIT T-cell: 163.9;memory B-cell: 165.9;memory CD4 T-cell: 192.1;memory CD8 T-cell: 187.4;naive B-cell: 181.2;naive CD4 T-cell: 177.1;naive CD8 T-cell: 171.1;NK-cell: 178.9;T-reg: 249.8" "Group enriched" "Detected in all" 9 "B-cells: 181.2;NK-cells: 178.9;T-cells: 249.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001945, HPA003894, HPA005437" Enhanced Supported Cytosol NA NA 430000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" Cytosol "CAB001945: , HPA003894: AB_1845360, HPA005437: AB_1078284" "unprognostic (2.20e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-2)" "unprognostic (9.65e-2)" "unprognostic (1.55e-1)" "unprognostic (1.08e-1)" "unprognostic (3.06e-2)" "unprognostic (2.21e-1)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-3)" "unprognostic (1.85e-1)" "unprognostic (1.42e-3)" "unprognostic (1.26e-2)" "unprognostic (2.57e-1)" "unprognostic (2.41e-3)" "unprognostic (3.22e-3)" 43.7 93.2 178.8 25.7 232.8 12.0 37.3 162.6 209.6 53.8 85.9 35.2 17.4 38.7 16.8 33.5 53.5 22.6 16.5 174.2 160.6 83.4 34.7 22.7 41.0 204.2 194.8 34.4 21.5 19.6 41.0 23.5 189.8 58.1 13.1 53.7 42.6 24.0 2105.3 14.8 31.5 19.6 155.4 54.7 45.0 10.4 199.2 18.4 28.5 803.2 27.5 89.0 36.6 310.5 52.0 27.9 32.8 39.3 95.9 76.5 11.4 15.3 33.1 35.8 23.4 107.6 31.3 0.0 46.0 28.9 20.8 6.8 14.6 25.0 9.5 5.9 4.1 15.1 46.9 7.1 86.2 0.2 2.8 70.2 6.1 77.3 14.0 46.4 49.1 5.1 3.2 1.6 44.8 1.1 4.9 43.3 24.8 114.2 31.4 11.8 36.3 4.8 126.7 0.1 22.4 61.9 55.5 21.2 17.7 34.7 1.3 9.7 59.3 40.9 39.9 52.8 52.1 1.3 1.4 0.3 60.3 2.6 19.2 1.2 3.1 0.6 186.6 2.0 163.9 165.9 192.1 187.4 15.1 181.2 177.1 171.1 6.0 178.9 3.2 21.5 249.8 133.5 178.8 232.8 162.6 209.6 174.2 160.6 204.2 194.8 189.8 155.4 199.2 310.5 15.6 9.6 10.0 10.7 80.1 18.6 10.0 3.3 1.2 144.1 10.7 9.1 5.6 44.3 5.5 14.7 125.1 1.8 98.3 18.6 37.2 15.2 16.1 11.7 46.2 21.9 46.0 11.6 36.9 29.4 4.2 68.7 29.0 19.0 2.5 28.7 15.0 18.3 164.9 30.3 47.2 28.0 10.2 27.0 62.3 55.8 78.6 50.1 23.2 58.1 10.4 25.3 176.1 11.6 186.4 16.7 18.1 30.5 14.6 26.2 14.3 255.7 1.4 133.4 13.1 75.7 28.8 2.6 10.9 1.6 8.9 2.9 98.2 40.0 50.1 9.8 CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.1;skin 1: 5.1" "Cell type enhanced" "Detected in some" "Club cells: 5.4;Collecting duct cells: 3.7;Endometrial stromal cells: 5.8;Leydig cells: 7.5;Pancreatic endocrine cells: 7.6;Suprabasal keratinocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.6;HDLM-2: 11.8;hTERT-RPE1: 12.5;TIME: 11.6;U-138 MG: 10.9;U-251 MG: 7.9" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA062460: AB_2732683, HPA068731: AB_2686023" "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-2)" "unprognostic (3.03e-1)" "unprognostic (7.75e-3)" "unprognostic (3.48e-1)" "unprognostic (2.31e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.81e-3)" "unprognostic (1.11e-1)" "unprognostic (6.29e-4)" "unprognostic (3.49e-4)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (8.64e-2)" 0.6 0.5 0.8 0.4 0.2 0.3 0.3 0.8 0.7 4.1 0.6 1.2 0.3 0.6 0.4 1.6 0.6 0.7 0.9 0.5 1.0 0.2 0.2 0.2 0.3 0.6 2.4 0.2 0.2 0.0 0.1 0.1 0.4 0.9 0.3 0.1 0.3 0.7 0.4 5.1 0.6 0.2 0.3 0.2 0.3 0.3 2.7 0.0 0.1 0.1 0.8 1.8 2.5 0.8 1.3 3.4 1.9 0.1 0.1 0.0 0.1 0.4 3.2 1.8 0.8 0.1 2.8 0.1 0.1 2.0 1.3 7.6 2.7 1.4 0.6 11.8 1.4 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.1 12.5 0.4 0.3 0.0 0.2 2.1 0.2 0.3 0.1 4.0 0.0 1.0 0.1 0.2 0.0 5.9 1.0 0.1 0.7 4.9 0.0 0.0 1.5 0.1 0.2 11.6 10.9 2.0 5.3 7.9 0.1 0.1 0.0 0.1 0.1 0.9 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.8 0.2 0.8 0.7 0.5 1.0 0.6 2.4 0.4 0.3 2.7 0.8 0.2 0.0 0.6 0.0 0.2 1.8 1.2 2.1 0.0 0.0 1.5 0.3 0.5 0.0 5.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 5.8 0.5 0.0 0.0 0.6 0.2 0.0 2.4 0.0 0.5 0.0 0.2 0.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.1 7.5 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 7.6 0.0 0.4 0.0 1.6 0.0 0.0 0.2 0.0 0.0 1.5 1.0 0.1 0.7 0.0 7.2 0.0 0.2 0.0 0.0 2.9 ERCC3 "BTF2, RAD25, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294166 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037153, HPA046077" Approved Enhanced Nucleoplasm NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "CAB037153: AB_796181, HPA046077: AB_2679527" "unprognostic (2.31e-1)" "unprognostic (1.15e-1)" "unprognostic (3.03e-2)" "unprognostic (1.07e-3)" "unprognostic (1.05e-1)" "unprognostic (8.85e-2)" "prognostic unfavorable (1.62e-7)" "unprognostic (2.74e-1)" "unprognostic (9.13e-3)" "unprognostic (9.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.46e-2)" "prognostic unfavorable (4.30e-6)" "unprognostic (3.71e-1)" "unprognostic (8.50e-2)" "unprognostic (5.73e-2)" "unprognostic (3.92e-2)" 24.4 25.9 15.0 14.5 16.0 19.8 24.4 15.1 16.5 32.2 19.6 28.9 9.6 27.0 11.6 22.7 28.9 14.2 23.4 16.6 14.9 22.8 22.2 22.1 21.6 15.7 14.8 29.5 23.8 26.3 33.8 13.6 16.0 27.4 13.8 4.4 23.2 16.8 35.3 27.7 24.3 21.5 15.1 32.6 23.7 29.8 15.6 26.6 25.0 25.6 22.4 27.2 26.4 15.2 45.9 30.8 37.8 40.6 40.6 27.8 46.4 41.3 52.9 65.1 62.5 48.1 32.9 34.5 33.2 37.8 41.7 40.2 57.7 43.3 56.1 54.4 51.4 43.6 35.8 51.0 30.5 38.1 45.4 28.9 39.8 75.7 32.4 41.5 42.4 44.3 43.0 22.1 41.7 45.1 54.8 42.2 55.0 29.2 47.3 44.5 42.7 28.8 36.4 42.2 45.2 49.2 35.3 52.6 55.0 42.4 28.7 43.0 34.1 39.2 45.2 35.8 49.7 39.2 81.5 54.0 34.3 18.0 42.8 8.0 11.5 8.8 18.2 12.0 18.4 13.7 13.1 15.7 16.9 12.7 17.7 12.2 3.5 25.0 9.9 13.6 20.5 15.5 15.0 16.0 15.1 16.5 16.6 14.9 15.7 14.8 16.0 15.1 15.6 15.2 12.2 22.4 14.6 24.8 17.7 7.6 9.5 20.6 21.1 0.0 13.0 11.6 13.0 5.7 25.4 7.3 0.0 18.6 18.9 6.1 1.9 13.7 9.0 22.9 13.9 12.2 6.1 3.8 22.3 14.9 12.2 16.6 18.8 13.1 10.1 17.1 15.4 8.6 14.6 0.0 23.5 10.0 14.2 12.5 7.6 5.1 16.4 10.7 8.8 10.3 12.3 0.0 14.4 18.1 22.4 15.5 7.3 12.8 16.4 7.4 6.3 8.5 45.2 0.0 13.1 17.6 13.3 41.1 31.0 11.3 9.5 14.6 15.7 12.3 10.6 8.5 MAP3K2 "MEKK2, MEKK2B" ENSG00000169967 "Mitogen-activated protein kinase kinase kinase 2" Q9Y2U5 2 127298730-127388465 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 11.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021540 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "HPA021540: AB_2670742" "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-1)" "unprognostic (9.46e-2)" "unprognostic (1.02e-1)" "unprognostic (5.76e-2)" "unprognostic (7.19e-2)" "unprognostic (4.50e-1)" "unprognostic (1.27e-1)" "unprognostic (4.00e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.97e-3)" "unprognostic (7.56e-2)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (2.11e-1)" 12.6 8.9 12.1 13.4 16.3 37.6 10.5 13.5 15.9 12.0 9.9 12.5 15.3 11.2 8.3 9.5 9.0 12.9 6.6 10.3 14.3 11.9 22.3 10.8 12.9 18.0 14.9 10.6 10.6 14.0 7.8 9.9 17.4 8.9 10.1 15.6 10.2 9.0 13.4 12.6 14.1 12.7 15.2 13.5 14.7 11.3 18.3 14.4 17.9 9.1 13.8 10.4 8.3 24.8 29.4 12.3 9.6 9.7 13.2 17.4 16.0 17.9 19.4 17.2 13.9 14.8 12.7 19.2 30.0 25.7 16.0 24.3 15.6 12.0 19.3 48.6 12.1 17.9 22.3 13.0 15.2 18.2 37.2 15.7 12.9 21.0 25.5 15.1 8.1 14.2 8.6 37.3 17.2 10.7 21.4 12.9 9.9 8.2 15.8 14.0 18.0 14.5 7.0 27.1 19.0 10.2 26.1 15.8 16.4 7.8 10.3 13.7 18.7 33.6 31.3 15.7 24.5 38.4 30.0 19.5 16.1 11.7 14.8 3.4 2.5 1.7 1.3 1.5 1.6 2.7 1.2 1.3 2.1 2.2 1.5 1.6 11.3 2.0 2.0 4.2 1.1 1.0 12.1 16.3 13.5 15.9 10.3 14.3 18.0 14.9 17.4 15.2 18.3 24.8 45.7 83.3 46.0 53.8 88.9 72.0 36.9 34.3 55.2 53.6 42.2 32.1 30.1 45.8 44.2 29.5 106.3 20.5 107.9 72.6 13.7 21.2 4.6 77.0 71.0 36.9 45.4 27.8 60.6 34.0 19.8 54.9 42.3 90.2 60.9 42.2 25.4 69.1 47.7 72.3 57.7 40.1 30.5 80.1 113.7 7.6 42.3 107.7 56.9 50.6 79.1 25.9 30.9 49.8 87.7 49.0 28.8 51.9 57.3 48.3 54.5 33.1 58.5 59.2 19.7 69.2 47.4 42.3 52.6 43.5 78.6 26.3 65.5 51.7 31.8 46.1 PROC ENSG00000115718 "Protein C, inactivator of coagulation factors Va and VIIIa" P04070 2 127418427-127429242 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 40 "liver: 598.5" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 432.9" "Cancer enriched" "Detected in many" 22 "liver cancer: 118.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 59.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 59.7" "Cell line enriched" "Detected in some" 16 "Hep G2: 156.1" "Low region specificity" "Detected in all" "HPA005550, CAB016721, CAB016792" Approved "Secreted to blood" NA NA 5200000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB016721: , CAB016792: , HPA005550: AB_1079687" "unprognostic (2.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (6.64e-2)" "unprognostic (3.13e-2)" "unprognostic (4.90e-3)" "unprognostic (2.63e-1)" "unprognostic (1.67e-1)" "unprognostic (3.29e-1)" "unprognostic (3.74e-3)" "unprognostic (2.56e-2)" "unprognostic (8.12e-3)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (4.60e-3)" "unprognostic (8.06e-2)" 0.2 0.0 0.6 0.1 1.1 1.1 0.1 0.6 1.0 0.4 0.0 1.0 0.8 0.1 0.1 0.1 0.2 0.6 0.1 0.6 1.0 14.8 598.5 0.2 0.6 1.6 0.8 0.2 0.3 0.0 0.3 0.1 1.5 0.2 0.6 0.2 0.2 0.1 0.2 0.6 0.8 0.0 0.4 0.4 2.6 0.1 0.8 0.6 0.2 0.0 0.3 0.4 0.2 1.1 0.1 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.1 0.0 0.9 0.1 0.4 9.5 0.0 0.3 0.0 0.0 0.2 0.1 7.8 156.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.3 1.6 0.4 2.3 0.7 0.0 0.1 0.0 0.0 0.9 0.4 0.0 1.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 6.3 0.0 0.0 59.7 0.0 0.3 0.6 1.1 0.6 1.0 0.6 1.0 1.6 0.8 1.5 0.4 0.8 1.1 0.0 0.0 0.0 0.3 4.1 0.8 0.4 11.2 0.0 0.0 0.1 0.0 0.4 47.1 1.2 0.0 0.0 0.0 24.0 3.9 5.9 0.5 0.1 3.4 0.1 0.6 10.3 18.7 0.1 0.2 0.0 0.7 2.0 0.2 0.0 0.0 12.1 432.9 3.7 0.0 0.5 9.3 0.0 9.3 4.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 8.1 0.0 0.0 0.0 3.8 84.8 3.4 0.0 0.0 0.2 0.3 0.1 0.2 0.0 0.1 0.1 1.1 0.0 1.8 0.3 IWS1 "DKFZp761G0123, FLJ10006, FLJ14655, FLJ32319" ENSG00000163166 "Interacts with SUPT6H, CTD assembly factor 1" Q96ST2 2 127436207-127526886 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035719, HPA061866" Supported Enhanced Nucleoplasm NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA035719: AB_10669527, HPA061866: AB_2684628" "unprognostic (3.11e-2)" "unprognostic (1.31e-1)" "unprognostic (1.80e-2)" "unprognostic (3.07e-2)" "unprognostic (1.44e-1)" "unprognostic (1.17e-2)" "unprognostic (8.49e-2)" "unprognostic (1.05e-1)" "unprognostic (4.27e-2)" "unprognostic (2.25e-1)" "unprognostic (4.32e-2)" "unprognostic (9.96e-2)" "unprognostic (1.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.10e-2)" "unprognostic (9.01e-2)" "unprognostic (9.81e-2)" 24.2 18.5 26.7 23.2 32.3 31.5 22.2 30.3 37.8 23.1 30.1 24.8 23.4 22.9 23.8 22.9 21.3 18.9 48.4 26.8 32.2 30.1 40.2 22.5 28.8 30.7 32.1 18.0 21.6 23.8 24.8 26.5 32.0 23.3 23.8 26.5 22.7 19.3 76.0 21.6 24.4 21.9 27.7 27.6 23.1 23.2 31.5 31.2 20.7 62.0 28.4 25.8 23.4 40.4 52.0 34.5 68.4 45.0 51.0 42.4 71.4 73.9 50.0 67.2 55.9 81.6 38.8 48.7 38.2 59.3 51.4 41.9 66.7 58.2 79.4 50.7 45.4 68.1 50.6 92.9 60.2 78.2 54.5 42.0 43.6 71.5 64.0 35.7 58.0 60.3 72.8 37.0 64.3 48.3 77.7 63.4 92.2 43.0 46.8 68.9 53.5 44.9 67.6 62.0 53.4 34.7 52.9 65.9 60.3 73.4 29.6 53.5 66.4 66.3 50.4 40.4 43.8 28.6 33.6 64.5 36.6 54.2 45.0 3.6 13.2 18.5 9.7 14.8 11.8 11.4 11.1 11.8 13.0 15.1 10.5 11.0 13.9 15.0 17.3 11.8 11.0 9.5 26.7 32.3 30.3 37.8 26.8 32.2 30.7 32.1 32.0 27.7 31.5 40.4 23.1 112.2 74.3 35.3 36.6 15.7 55.3 22.8 23.9 27.9 16.9 15.7 77.4 21.5 53.5 16.5 27.1 40.0 33.5 35.1 19.6 38.6 13.2 38.5 39.8 28.9 28.1 30.7 21.9 25.5 56.3 41.9 32.1 36.8 42.3 42.3 20.7 25.7 27.1 21.9 27.8 25.7 30.5 16.4 25.4 8.5 39.1 29.2 10.6 25.3 40.1 26.4 46.4 25.6 105.0 41.9 28.0 31.6 37.5 53.8 25.1 19.1 44.6 44.7 32.9 29.3 35.6 69.8 52.0 24.1 17.0 92.8 37.4 34.6 26.9 77.2 MYO7B ENSG00000169994 "Myosin VIIB" Q6PIF6 2 127535802-127637729 "Predicted intracellular proteins" Differentiation "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 113.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 127.7;Intestinal goblet cells: 48.3;Paneth cells: 74.9;Proximal enterocytes: 151.4;Undifferentiated cells: 45.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 17.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.7;naive B-cell: 5.9" "Group enriched" "Detected in many" 22 "B-cells: 5.9;dendritic cells: 2.6;monocytes: 5.7" "Cell line enriched" "Detected in some" 10 "MOLT-4: 286.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA039131 Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" "HPA039131: AB_10672771" "unprognostic (4.10e-3)" "unprognostic (3.81e-2)" "unprognostic (3.80e-2)" "unprognostic (2.23e-4)" "unprognostic (1.14e-2)" "unprognostic (2.23e-1)" "unprognostic (2.07e-1)" "unprognostic (8.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.03e-1)" "prognostic favorable (1.25e-4)" "unprognostic (2.80e-2)" "unprognostic (8.76e-2)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" 0.1 0.0 0.2 4.9 0.2 6.5 0.1 0.2 0.3 0.0 0.0 35.9 113.2 0.0 6.7 0.3 0.4 13.0 0.2 0.7 1.8 8.5 0.3 1.0 4.0 0.5 1.1 0.0 0.2 0.0 0.0 1.7 1.1 0.1 25.3 0.0 0.1 0.2 0.8 0.3 84.4 1.2 0.5 11.3 0.4 1.4 0.3 9.0 0.2 0.0 1.6 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 14.5 5.1 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.2 0.0 28.1 0.0 0.0 0.2 0.0 286.1 0.8 0.0 0.5 1.7 0.5 1.9 0.3 0.5 0.0 0.1 0.1 0.0 2.4 0.0 0.0 0.1 0.5 0.1 0.6 8.6 0.4 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.7 0.1 0.0 2.2 0.0 0.8 0.0 0.0 2.6 5.9 0.0 0.2 0.1 0.0 1.4 0.7 0.0 2.4 0.2 0.2 0.2 0.3 0.7 1.8 0.5 1.1 1.1 0.5 0.3 0.8 2.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 12.8 0.0 5.5 0.0 0.1 1.5 127.7 1.9 0.2 0.1 0.0 0.0 1.0 25.8 0.0 0.2 0.2 2.0 0.1 1.5 0.0 0.0 0.1 2.9 0.2 0.1 0.0 0.4 48.3 0.0 0.0 0.3 0.4 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.5 0.1 1.6 74.9 0.0 0.0 0.0 151.4 9.9 0.0 0.0 0.0 2.8 0.1 0.6 1.1 0.0 0.1 0.3 0.6 0.0 45.7 0.1 LIMS2 "PINCH-2, PINCH2" ENSG00000072163 "LIM zinc finger domain containing 2" Q7Z4I7 2 127638381-127681786 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 510.1" "Cell type enhanced" "Detected in many" "Adipocytes: 109.4;Cardiomyocytes: 91.7;Endothelial cells: 105.1;Granulosa cells: 134.1;Hepatic stellate cells: 134.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 22.5" "Group enriched" "Detected in many" 13 "B-cells: 22.5;T-cells: 10.7" "Cell line enhanced" "Detected in many" "BJ hTERT+: 27.0;fHDF/TERT166: 31.2;HHSteC: 32.7;MOLT-4: 40.2;TIME: 83.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058340 Enhanced Supported "Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" "HPA058340: AB_2683683" "unprognostic (2.51e-2)" "unprognostic (1.25e-1)" "unprognostic (5.82e-3)" "unprognostic (4.51e-2)" "unprognostic (9.25e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.53e-7)" "unprognostic (3.98e-2)" "unprognostic (3.73e-1)" "unprognostic (2.29e-1)" "unprognostic (3.78e-2)" "unprognostic (8.86e-2)" "unprognostic (3.33e-1)" "unprognostic (4.60e-3)" "unprognostic (3.64e-2)" "unprognostic (1.77e-1)" "unprognostic (4.00e-2)" 104.6 21.6 29.4 17.9 27.9 0.4 93.9 24.9 32.3 104.4 25.1 510.1 15.8 261.4 16.9 42.1 139.5 25.7 266.4 25.6 24.1 72.7 46.6 114.3 12.9 28.7 27.2 29.0 14.1 6.4 15.6 27.7 29.3 132.1 15.2 0.6 27.1 98.8 33.4 32.8 95.7 81.9 24.3 121.8 123.1 12.0 32.2 13.1 51.6 26.8 5.4 220.5 85.1 24.0 0.8 1.6 0.5 0.0 4.6 1.0 0.3 19.1 27.0 20.2 18.1 4.7 0.1 0.1 10.3 31.2 1.1 0.1 0.3 0.0 4.2 0.0 0.8 0.0 11.9 3.6 32.7 0.0 0.0 0.2 0.0 7.0 0.2 10.7 12.9 15.3 0.0 0.0 10.0 0.0 40.2 1.0 1.3 0.0 2.4 9.0 1.7 1.0 1.3 0.0 0.1 0.2 3.0 1.7 0.7 6.7 0.7 0.0 83.7 0.1 12.9 15.2 0.1 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.3 0.0 15.2 5.3 1.1 0.2 22.5 10.7 4.4 0.3 0.0 0.2 1.2 8.0 2.5 29.4 27.9 24.9 32.3 25.6 24.1 28.7 27.2 29.3 24.3 32.2 24.0 109.4 22.4 6.1 0.3 10.1 9.4 0.3 0.2 1.2 0.2 1.9 17.1 91.7 4.3 1.3 0.0 0.0 0.6 0.8 0.1 0.0 1.2 1.3 2.9 5.3 105.1 0.0 5.7 0.4 0.2 12.4 22.5 1.1 0.9 2.5 134.1 134.6 16.3 1.0 0.0 0.3 0.0 0.0 6.5 13.0 3.1 19.9 1.7 10.6 30.9 0.0 0.3 0.0 4.0 0.3 0.5 0.0 49.7 1.7 0.3 0.0 0.5 0.8 0.9 26.3 4.2 35.4 0.8 2.1 0.6 6.7 1.0 2.3 1.8 0.0 0.3 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 58 "Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cell line enhanced" "Detected in some" "HeLa: 3.1;REH: 4.4;TIME: 4.3;U-2 OS: 1.7;U-2197: 2.0;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 9.8 1.1 9.1 3.4 6.3 0.1 7.9 4.7 9.7 3.6 3.5 23.8 1.5 14.8 1.4 2.4 5.3 2.1 19.8 6.4 5.5 3.0 2.6 9.3 1.1 7.2 7.5 1.8 2.2 0.0 0.7 1.2 7.2 5.5 0.1 0.1 2.0 0.0 7.5 3.4 6.0 0.0 6.4 7.5 5.8 0.9 7.7 0.1 3.8 0.2 0.0 8.8 5.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.2 0.1 0.0 4.3 0.0 1.7 2.0 2.6 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 6.3 4.7 9.7 6.4 5.5 7.2 7.5 7.2 6.4 7.7 8.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 58.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 WDR33 "FLJ11294, NET14, WDC146" ENSG00000136709 "WD repeat domain 33" Q9C0J8 2 127701027-127811187 "Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026897, HPA046527" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Nucleoli fibrillar center" "HPA026897: AB_1858803, HPA046527: AB_2679686" "unprognostic (1.26e-1)" "unprognostic (7.22e-2)" "unprognostic (1.50e-1)" "unprognostic (1.79e-2)" "unprognostic (6.63e-2)" "unprognostic (8.32e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.01e-1)" "unprognostic (1.66e-2)" "unprognostic (8.13e-2)" "unprognostic (5.72e-3)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" "unprognostic (3.64e-1)" "unprognostic (2.04e-1)" "unprognostic (9.85e-2)" "unprognostic (1.03e-2)" 20.2 16.1 16.2 18.5 16.9 17.3 20.4 35.0 19.0 24.5 19.8 21.9 14.7 19.9 14.4 20.9 21.6 11.8 20.0 16.2 17.0 19.9 27.9 18.9 22.0 15.0 16.5 27.8 20.1 19.1 23.0 16.8 16.3 22.1 15.1 24.5 19.3 12.9 21.2 26.6 22.2 15.0 14.2 27.8 18.5 20.6 16.6 30.9 24.2 21.3 23.9 19.9 22.9 20.0 40.3 22.3 38.2 31.2 22.3 22.9 39.0 36.0 28.5 37.3 35.2 52.1 30.3 50.5 39.0 24.0 34.4 31.8 43.6 30.5 48.6 46.5 26.0 48.9 28.2 56.6 25.1 59.7 35.1 22.4 31.7 35.9 30.3 26.7 32.4 45.0 41.5 44.4 26.6 25.1 62.3 43.7 46.5 25.9 24.6 43.1 38.6 40.4 21.5 51.6 35.5 27.5 32.3 29.6 26.0 35.7 23.0 34.4 29.8 29.3 42.6 33.0 31.1 42.8 70.5 96.4 23.9 23.4 27.8 35.7 20.6 35.1 24.9 22.7 25.8 30.5 25.2 24.2 27.4 28.3 26.6 25.7 14.1 34.7 25.0 19.7 34.4 18.5 16.2 16.9 35.0 19.0 16.2 17.0 15.0 16.5 16.3 14.2 16.6 20.0 63.0 35.3 45.0 47.3 77.9 110.0 77.3 83.8 51.2 50.7 41.3 41.4 46.5 64.3 51.5 36.8 64.6 80.7 74.7 31.4 46.9 48.1 42.4 38.3 39.8 55.0 39.4 35.9 66.2 44.8 87.9 49.3 40.8 47.4 64.7 49.8 43.2 72.5 49.5 60.6 68.9 36.6 75.3 42.0 82.0 25.2 50.4 50.8 76.5 45.0 69.2 32.2 64.9 73.4 83.5 38.9 37.0 50.4 110.1 51.2 42.3 56.7 35.6 61.3 46.0 48.8 71.3 113.3 81.2 53.7 115.8 110.5 79.2 59.7 43.2 65.5 SFT2D3 MGC5391 ENSG00000173349 "SFT2 domain containing 3" Q587I9 2 127701497-127705242 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 7.4;ASC TERT1: 4.2;BJ hTERT+: 4.2;HHSteC: 5.0;hTCEpi: 7.0;hTERT-HME1: 5.2;RPTEC TERT1: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" 0.9 0.0 2.4 0.0 2.4 0.0 5.2 2.4 3.1 3.8 2.4 3.3 0.0 1.2 6.1 0.0 4.1 0.0 0.0 2.4 2.4 3.2 6.0 1.6 0.0 2.5 2.6 1.3 1.0 5.0 0.0 1.6 2.5 2.8 5.5 0.0 0.0 3.5 0.0 0.0 0.0 2.9 2.4 1.1 1.5 1.3 2.4 4.7 1.0 2.6 4.8 1.0 0.0 2.5 0.0 0.0 0.0 0.0 7.4 4.2 0.0 0.0 4.2 4.1 3.2 0.0 0.0 0.0 0.0 3.1 0.0 0.0 3.5 2.9 3.3 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 3.8 7.0 2.0 5.2 0.0 4.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 2.4 2.4 3.1 2.4 2.4 2.5 2.6 2.5 2.4 2.4 2.5 6.9 3.2 6.8 1.6 7.6 1.3 8.2 1.6 5.7 7.9 7.1 7.0 0.0 2.8 1.5 7.3 16.7 4.2 9.5 6.4 9.8 2.8 4.9 9.3 8.7 5.2 5.4 5.5 1.8 6.2 4.4 6.4 7.7 7.4 1.3 7.5 4.2 9.5 4.1 8.4 2.5 10.5 0.0 8.4 3.0 2.7 5.6 10.5 3.6 3.7 5.1 10.0 8.2 3.0 5.1 3.1 7.0 7.5 5.6 9.3 5.6 6.4 3.4 10.1 0.0 5.2 5.2 18.3 3.8 7.1 2.7 2.9 6.5 9.7 8.7 5.9 POLR2D RPB4 ENSG00000144231 "RNA polymerase II subunit D" O15514 2 127843553-127858155 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 74.3" "Cell type enhanced" "Detected in all" "Late spermatids: 170.2;Spermatocytes: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034694, HPA046092" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear speckles" "HPA034694: AB_2674284, HPA046092: AB_10963049" "unprognostic (3.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.59e-1)" "unprognostic (2.54e-2)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.91e-4)" "unprognostic (2.51e-1)" "unprognostic (7.95e-3)" "unprognostic (2.64e-3)" "unprognostic (1.97e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (3.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.17e-1)" "unprognostic (2.38e-1)" 12.3 10.4 7.2 14.4 9.8 32.4 11.9 9.6 8.3 9.4 7.3 12.0 9.7 10.3 8.0 12.3 10.6 8.4 10.0 7.5 8.7 8.8 19.2 10.2 19.7 8.0 8.9 15.0 14.7 10.4 8.3 15.9 8.3 9.5 14.7 8.1 8.4 9.2 29.3 11.3 9.3 15.0 8.4 12.8 9.4 74.3 8.1 28.3 9.1 27.1 26.9 15.3 8.4 11.0 63.4 40.6 73.9 51.9 26.8 29.2 59.0 59.1 27.9 69.6 61.9 92.0 50.9 97.7 49.6 40.0 39.8 32.7 107.0 51.2 107.3 57.7 58.3 96.6 37.9 85.4 31.4 104.9 51.6 20.8 37.8 93.3 53.2 19.3 46.1 70.4 137.1 84.8 40.4 50.1 105.0 47.5 103.6 65.9 46.4 99.3 77.8 88.0 23.1 42.6 45.7 60.9 39.9 48.9 50.7 54.7 54.6 71.4 47.0 60.1 84.4 34.4 69.0 99.4 173.4 173.0 52.4 51.2 60.5 9.9 22.8 17.3 26.3 31.7 25.0 22.8 21.0 23.2 29.9 20.2 27.6 23.7 7.3 25.8 35.0 19.5 20.6 21.3 7.2 9.8 9.6 8.3 7.5 8.7 8.0 8.9 8.3 8.4 8.1 11.0 10.9 3.2 11.7 2.6 22.0 10.8 22.0 7.6 15.9 15.1 9.8 6.2 10.4 11.5 10.1 12.9 8.4 33.0 23.4 7.6 11.7 20.3 70.8 13.2 16.1 12.5 8.4 31.1 4.7 17.5 31.0 15.2 9.7 10.4 18.4 23.1 11.4 17.0 21.7 33.7 5.2 11.9 8.2 11.1 14.1 170.2 17.7 13.3 8.8 2.8 23.4 13.2 16.5 2.5 7.5 18.4 8.4 18.4 46.6 26.2 10.2 11.1 6.8 13.7 13.1 18.5 15.5 86.1 48.9 19.3 10.1 26.7 17.1 31.5 14.0 18.9 AMMECR1L MGC4268 ENSG00000144233 "AMMECR1 like" Q6DCA0 2 127861630-127885967 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000590, HPA057234" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Cytosol "HPA000590: AB_2666037, HPA057234: AB_2683376" "unprognostic (1.34e-1)" "unprognostic (1.29e-3)" "unprognostic (8.95e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.92e-1)" "unprognostic (9.10e-2)" "unprognostic (2.66e-2)" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (4.98e-2)" "unprognostic (2.27e-2)" "unprognostic (4.06e-3)" "unprognostic (7.75e-2)" "unprognostic (4.54e-1)" "unprognostic (1.12e-2)" "unprognostic (8.91e-2)" 12.4 10.1 3.1 3.4 3.3 2.4 10.9 3.2 3.8 12.1 2.6 9.9 4.5 12.1 2.4 10.0 11.5 5.0 9.4 3.2 3.4 9.2 12.7 8.9 3.7 3.4 3.3 10.8 10.5 8.5 7.2 7.4 3.3 9.7 4.6 2.3 8.9 5.7 8.3 11.4 9.4 7.3 2.9 10.1 9.6 12.7 3.8 5.4 9.0 7.9 5.1 9.4 11.4 3.2 8.0 5.6 16.4 12.3 15.7 12.0 11.1 10.0 14.4 13.6 14.6 15.0 7.4 6.5 6.6 18.2 6.0 7.7 17.2 10.5 17.9 13.1 9.8 5.7 5.4 11.2 18.3 9.7 9.6 15.6 21.9 18.8 18.4 12.6 19.1 9.5 8.3 5.4 14.6 4.7 10.3 2.7 11.3 9.7 14.1 11.0 15.7 4.7 10.1 3.7 11.0 11.9 12.9 16.2 27.0 14.1 7.0 8.6 13.4 16.6 9.0 5.4 8.5 5.6 11.1 7.6 7.7 7.7 12.5 0.5 1.2 3.8 1.5 1.3 2.0 1.4 1.6 1.5 1.7 1.6 1.4 1.1 1.8 1.6 1.6 1.8 1.4 1.3 3.1 3.3 3.2 3.8 3.2 3.4 3.4 3.3 3.3 2.9 3.8 3.2 9.8 19.2 8.1 5.9 7.2 18.0 8.6 4.8 9.6 5.3 14.5 9.7 12.0 10.0 9.2 3.7 6.2 5.9 7.1 8.6 0.0 6.2 11.4 11.8 27.0 10.4 5.4 5.0 10.4 5.8 7.7 11.1 10.2 12.6 7.0 10.2 8.2 16.2 4.6 1.7 9.2 9.4 2.0 7.5 6.6 15.1 6.8 5.8 5.4 8.4 4.4 4.2 3.1 7.5 10.8 9.2 6.7 8.2 12.2 14.8 5.5 4.6 14.7 6.0 0.0 15.4 11.8 6.6 9.8 13.2 15.8 7.7 7.0 6.4 9.3 13.9 SAP130 FLJ12761 ENSG00000136715 "Sin3A associated protein 130" Q9H0E3 2 127941217-128028120 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Cell type enhanced" "Detected in many" "Early spermatids: 71.5;Late spermatids: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034664 Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nuclear speckles" "HPA034664: AB_10603238" "unprognostic (2.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-1)" "unprognostic (5.45e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (2.75e-1)" "unprognostic (1.30e-2)" "unprognostic (1.43e-1)" "unprognostic (3.92e-2)" "unprognostic (6.77e-2)" "unprognostic (3.75e-2)" "unprognostic (5.26e-2)" "unprognostic (4.41e-1)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" 9.1 8.6 8.8 8.7 8.5 21.7 8.2 8.5 10.2 10.5 5.1 10.3 8.3 10.4 9.2 10.4 9.6 7.2 8.5 8.1 10.8 7.2 8.3 8.0 10.0 6.4 7.9 11.2 8.7 12.4 14.5 9.0 7.1 8.7 9.7 8.6 9.1 7.9 11.9 12.9 9.8 10.2 6.1 8.5 9.7 47.3 8.0 14.8 8.8 13.0 12.6 9.5 10.3 8.8 35.3 18.9 35.3 28.6 22.9 15.7 38.5 22.0 21.4 33.4 26.2 45.1 14.4 29.4 19.3 25.0 17.4 24.0 39.3 22.7 34.5 16.3 25.2 29.2 16.7 35.9 27.5 25.5 22.2 14.8 16.7 44.1 27.5 17.6 27.0 24.4 35.9 21.1 28.2 39.3 35.6 20.0 36.6 20.7 21.1 24.3 29.0 19.6 17.9 30.7 18.5 22.3 23.2 21.7 13.6 22.1 16.4 17.3 23.2 32.1 34.5 30.1 23.6 29.3 31.2 34.3 26.4 17.0 21.0 2.3 4.2 4.6 5.3 2.7 4.0 2.0 3.8 3.5 3.4 5.0 2.7 3.1 14.0 3.6 8.6 6.2 2.7 3.8 8.8 8.5 8.5 10.2 8.1 10.8 6.4 7.9 7.1 6.1 8.0 8.8 5.4 0.0 10.9 29.0 7.9 7.9 2.3 3.2 5.7 5.2 6.5 5.3 15.2 2.8 3.1 1.8 8.4 11.9 9.4 13.1 0.0 4.9 71.5 4.6 8.6 6.2 6.7 11.6 25.4 4.7 12.8 5.2 8.6 8.7 1.3 5.3 5.3 5.8 7.8 8.4 28.9 7.0 4.1 8.4 6.3 44.2 8.4 7.0 5.4 16.9 4.9 5.0 6.2 26.2 31.0 6.1 7.8 8.2 13.2 4.9 6.5 3.4 4.0 5.8 6.6 4.4 5.5 31.0 17.9 9.2 10.4 19.3 7.6 3.7 7.8 4.3 UGGT1 "HUGT1, UGCGL1" ENSG00000136731 "UDP-glucose glycoprotein glucosyltransferase 1" Q9NYU2 2 128091200-128195677 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012761, HPA015127" Enhanced Uncertain Cytosol NA NA 4000000 "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 52: Non-specific - Transcription" Cytosol "HPA012761: AB_1858597, HPA015127: AB_1858596" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.14e-2)" "unprognostic (1.87e-1)" "unprognostic (4.63e-2)" "unprognostic (6.45e-2)" "unprognostic (7.03e-3)" "unprognostic (3.13e-2)" "unprognostic (3.02e-2)" "unprognostic (1.05e-1)" "unprognostic (4.09e-3)" "unprognostic (7.05e-2)" "prognostic unfavorable (6.37e-4)" "unprognostic (3.86e-1)" "unprognostic (1.50e-1)" "unprognostic (2.23e-2)" "unprognostic (8.38e-3)" 8.1 8.5 4.2 13.7 4.6 21.8 7.6 4.8 6.5 9.1 5.0 12.4 9.0 7.3 19.9 8.0 6.5 6.5 8.0 4.3 4.6 8.2 14.9 8.4 12.3 4.7 4.4 5.1 14.8 8.7 6.5 8.7 5.0 8.7 10.0 9.7 8.6 6.2 13.2 8.8 10.2 6.2 4.0 9.4 10.7 6.4 4.8 11.7 10.4 13.0 12.6 7.5 6.6 5.6 34.8 11.8 22.0 47.6 28.0 22.3 34.3 39.4 16.7 12.7 11.3 26.0 24.9 49.4 15.4 28.3 11.3 25.3 16.8 16.8 25.5 31.5 8.2 43.4 14.9 82.3 28.0 58.6 25.9 16.3 13.0 25.4 23.0 25.0 29.8 19.8 28.4 25.6 26.9 24.4 23.5 33.5 39.5 24.0 12.4 19.2 21.3 20.9 23.8 25.2 11.7 17.4 27.3 36.0 24.4 22.5 14.4 40.2 43.1 34.6 24.4 20.1 28.4 27.3 40.4 22.3 29.3 31.4 32.6 3.8 2.5 2.5 2.3 2.5 2.3 1.6 1.9 2.1 1.9 3.3 1.6 2.3 3.7 1.9 2.5 3.1 1.6 1.4 4.2 4.6 4.8 6.5 4.3 4.6 4.7 4.4 5.0 4.0 4.8 5.6 14.6 35.3 24.7 24.8 14.3 8.2 6.4 11.1 5.7 19.8 11.2 7.1 16.7 12.8 20.7 3.7 22.9 10.5 22.1 21.5 1.9 14.0 9.2 18.4 27.7 16.5 22.8 31.5 40.6 19.5 20.1 16.6 21.9 22.2 11.4 20.8 17.9 39.7 16.6 20.2 37.6 21.9 8.2 25.4 16.4 2.3 14.9 20.0 14.2 32.8 26.0 7.5 15.5 31.2 46.5 19.4 10.4 13.5 31.5 13.3 25.3 8.4 12.7 20.2 6.6 18.5 13.3 10.0 8.5 9.4 10.7 10.8 18.9 16.0 22.8 10.1 HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 75.4;Granulosa cells: 285.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 131.2;HMC-1: 206.6;SCLC-21H: 112.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044586 Approved Nucleoplasm "Intracellular and membrane" NA NA 72000 "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA044586: AB_10963057" "unprognostic (9.94e-2)" "unprognostic (8.93e-3)" "unprognostic (4.94e-3)" "unprognostic (6.69e-3)" "unprognostic (1.99e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (2.87e-1)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" 16.2 63.4 36.2 8.8 33.8 5.1 16.1 24.4 45.5 15.5 10.9 15.4 8.7 12.3 6.1 34.1 17.5 21.0 19.0 35.4 26.5 71.4 46.8 17.0 8.4 32.1 34.7 26.4 30.8 8.8 15.2 12.0 33.6 28.2 6.9 26.4 26.0 22.8 36.2 26.5 15.1 6.4 31.2 32.1 12.7 25.0 39.9 14.5 14.2 18.7 7.4 19.4 23.1 28.9 12.5 17.4 46.0 26.5 17.5 32.5 24.7 15.1 19.1 14.8 8.1 9.0 8.0 11.9 131.2 19.4 6.9 32.5 17.5 29.1 5.5 19.9 18.1 10.5 6.4 87.9 21.1 18.4 206.6 43.9 33.9 11.9 3.6 4.9 8.0 31.8 6.7 12.1 5.4 25.7 49.6 81.0 55.3 4.7 10.7 16.1 12.6 61.9 13.4 36.3 112.9 28.4 12.1 30.1 6.7 30.6 12.2 6.9 9.6 13.1 28.9 49.1 12.3 7.2 7.6 2.7 7.9 13.0 9.7 3.0 0.7 0.6 1.0 0.4 0.1 0.7 0.4 0.6 0.5 0.7 0.4 0.4 0.2 0.2 1.5 2.3 0.2 0.6 36.2 33.8 24.4 45.5 35.4 26.5 32.1 34.7 33.6 31.2 39.9 28.9 9.5 25.6 8.9 20.9 4.9 16.2 11.2 16.1 14.8 9.4 15.1 12.8 7.3 10.0 10.3 75.4 31.3 9.7 7.3 22.3 5.9 15.4 0.9 22.9 11.5 12.6 3.0 6.9 24.2 5.8 36.9 12.6 4.1 39.7 57.0 285.6 30.0 23.8 10.7 21.9 20.3 6.5 8.2 14.2 9.2 3.3 11.8 9.1 7.2 5.6 6.7 8.2 1.0 6.6 10.4 6.6 12.0 17.0 3.2 9.7 6.9 3.3 8.7 32.8 6.6 7.6 9.4 1.1 3.1 18.3 17.0 23.3 3.5 27.1 3.7 8.9 RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;breast: 2.5;parathyroid gland: 3.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 10.3;Oligodendrocytes: 3.3" "Group enriched" "Detected in some" 5 "breast cancer: 0.7;prostate cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.5;HMC-1: 2.2;REH: 5.4;T-47d: 3.2;U-266/70: 2.1" HPA059131 Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 6: T47d - Mammary gland" "Cluster 43: Cardiomyocytes - Nuclear processes" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (3.84e-2)" "unprognostic (5.77e-2)" "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (2.54e-1)" "unprognostic (8.62e-2)" "unprognostic (1.83e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (2.44e-1)" "unprognostic (1.33e-1)" "unprognostic (4.48e-2)" "unprognostic (6.04e-2)" "unprognostic (1.24e-1)" "unprognostic (4.78e-1)" 0.1 0.6 1.4 0.1 2.2 0.0 2.5 0.7 1.9 1.9 0.7 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.2 1.3 1.6 0.1 0.0 0.0 0.0 1.2 1.2 0.1 0.0 3.6 0.2 0.3 1.3 1.7 0.0 0.3 0.0 0.4 0.1 0.0 0.1 0.0 0.7 0.5 0.0 0.9 1.6 0.0 0.1 0.0 0.0 0.0 0.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.1 0.5 3.2 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 0.7 1.9 1.3 1.6 1.2 1.2 1.3 0.7 1.6 3.6 0.1 0.0 0.0 0.3 0.1 0.8 0.3 0.3 0.0 0.0 0.9 0.1 10.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.1 1.7 1.0 0.0 0.0 0.7 0.0 1.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.3 0.4 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.0 0.6 0.7 0.0 0.1 0.0 0.0 0.6 1.4 1.4 1.3 0.0 1.1 0.5 0.1 0.1 0.1 0.3 POTEF "A26C1B, POTE2alpha, POTEACTIN" ENSG00000196604 "POTE ankyrin domain family member F" A5A3E0 2 130073535-130129222 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 1.6;testis: 1.7" "Cell type enhanced" "Detected in some" "Melanocytes: 1.8;NK-cells: 1.0;Smooth muscle cells: 1.3;Spermatocytes: 2.2;Spermatogonia: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;BEWO: 2.0;CACO-2: 2.3;MCF7: 1.8;U-2 OS: 5.6;U-266/70: 2.7" "HPA041264, HPA041271, HPA043260" Uncertain NA NA 1900000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-1)" "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (8.13e-3)" "unprognostic (1.44e-2)" "unprognostic (2.90e-2)" "unprognostic (1.16e-1)" "unprognostic (3.38e-1)" "unprognostic (2.23e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" "unprognostic (4.48e-1)" "unprognostic (1.05e-2)" "unprognostic (9.35e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 2.7 0.0 0.0 2.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.1 2.7 0.8 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 1.6 0.1 0.2 0.0 0.0 0.2 1.6 0.9 0.5 0.5 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.3 2.2 1.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 CCDC74B DKFZp434E2321 ENSG00000152076 "Coiled-coil domain containing 74B" Q96LY2 2 130139287-130145134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.4" "Cell type enhanced" "Detected in many" "Early spermatids: 322.3;Late spermatids: 129.6;Respiratory ciliated cells: 70.3;Spermatocytes: 142.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 10.2;SH-SY5Y: 14.8" HPA060727 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA060727: " "prognostic favorable (4.46e-4)" "unprognostic (4.75e-3)" "unprognostic (2.67e-1)" "unprognostic (2.76e-3)" "unprognostic (2.81e-1)" "unprognostic (1.73e-1)" "unprognostic (8.69e-3)" "unprognostic (9.43e-2)" "unprognostic (2.99e-1)" "unprognostic (2.10e-1)" "unprognostic (6.43e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.43e-2)" "unprognostic (1.48e-4)" "unprognostic (8.31e-3)" "unprognostic (9.94e-3)" 1.5 1.9 3.5 0.3 3.6 0.0 2.4 2.6 4.3 17.0 7.6 1.6 0.2 8.9 0.8 0.4 14.1 1.4 1.5 4.1 5.4 3.8 0.1 2.8 0.3 6.2 7.2 5.0 0.8 11.1 19.7 0.2 5.1 7.1 0.1 0.6 0.6 2.8 0.2 1.0 0.7 1.2 5.7 0.4 1.5 55.4 6.1 0.6 7.0 0.0 0.2 2.4 3.6 3.9 0.0 1.9 2.8 0.1 2.5 5.4 0.6 2.2 1.1 0.3 0.5 0.9 0.7 0.1 3.5 2.0 3.2 1.0 0.2 0.3 0.4 2.0 5.5 0.0 7.0 0.1 0.3 0.1 0.2 1.1 0.0 0.9 0.0 3.4 0.1 1.3 0.1 1.7 0.8 2.1 0.0 0.0 5.7 0.5 5.9 4.6 0.0 3.2 1.7 0.0 10.2 14.8 1.6 0.1 0.2 0.6 5.9 0.7 0.4 1.1 4.8 5.9 0.5 0.1 0.3 0.0 6.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.6 4.3 4.1 5.4 6.2 7.2 5.1 5.7 6.1 3.9 0.2 3.2 0.5 1.6 0.1 0.5 3.0 6.3 1.2 0.5 6.1 9.5 0.4 1.5 4.3 5.5 0.0 0.2 0.2 0.1 3.9 1.5 322.3 42.8 9.9 0.2 11.4 0.0 1.6 0.2 0.8 3.6 0.0 2.2 0.0 7.8 0.0 0.0 0.3 3.3 1.1 0.1 2.0 0.0 0.2 129.6 10.2 0.6 0.0 1.0 0.0 6.2 0.0 0.5 0.3 0.0 0.1 12.4 0.1 3.9 0.0 1.2 70.3 0.1 0.0 0.9 3.2 142.7 16.4 0.7 1.1 0.1 0.3 28.8 0.1 0.7 SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nuclear membrane" Cytosol "HPA046279: AB_2679611, HPA049426: AB_2680762" "unprognostic (5.02e-2)" "unprognostic (9.61e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.69e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (3.27e-2)" "unprognostic (1.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (1.73e-4)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.74e-1)" "unprognostic (2.28e-1)" "unprognostic (1.47e-3)" "unprognostic (2.09e-1)" 9.9 10.8 4.2 11.1 4.9 25.4 10.9 5.3 6.2 15.5 3.1 12.1 9.5 15.5 5.0 13.8 15.9 9.2 11.7 4.0 7.0 8.6 9.2 10.6 15.7 7.5 5.0 14.6 13.3 15.2 22.7 14.9 6.3 11.8 11.1 4.7 12.9 11.7 13.3 13.5 11.5 12.9 2.4 11.2 10.3 17.7 6.0 19.8 16.0 12.0 15.7 11.8 12.3 10.0 89.1 41.5 46.2 39.2 29.1 21.8 58.7 41.5 42.0 76.3 62.8 119.2 47.0 56.2 41.2 49.9 36.3 43.8 64.0 64.4 40.4 72.7 61.2 60.5 36.2 90.1 31.2 68.5 34.7 25.6 39.4 77.0 27.2 21.1 44.9 51.4 82.2 40.8 40.7 44.3 72.2 32.0 77.0 40.1 56.4 74.3 44.2 59.0 27.0 38.6 66.8 36.3 42.8 54.5 22.7 24.9 37.8 34.8 32.8 57.0 49.3 33.0 49.4 34.3 44.0 79.2 51.4 38.7 44.0 1.8 9.2 14.8 12.9 11.2 14.3 8.9 9.6 11.6 9.6 9.1 9.0 10.5 4.3 12.1 8.1 6.0 9.2 10.4 4.2 4.9 5.3 6.2 4.0 7.0 7.5 5.0 6.3 2.4 6.0 10.0 17.4 3.2 11.3 4.9 20.8 15.0 9.1 8.8 12.0 19.8 21.5 23.0 3.9 5.7 8.0 7.3 12.5 23.8 16.4 7.9 9.8 9.2 22.7 16.0 19.7 12.0 13.1 21.2 6.9 12.2 26.5 12.2 18.8 26.3 6.3 29.0 10.4 17.3 14.1 15.2 6.7 12.8 4.1 13.2 7.7 41.7 14.6 10.2 16.0 1.0 8.8 9.9 11.3 7.5 10.4 11.8 10.5 18.4 27.0 9.4 7.7 5.9 9.9 16.0 0.0 14.1 12.8 25.0 25.6 18.7 20.6 15.6 15.6 16.0 15.2 9.6 MZT2B "FAM128B, FLJ14346, MOZART2B" ENSG00000152082 "Mitotic spindle organizing protein 2B" Q6NZ67 2 130181737-130190729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1258.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 962.4" "Low region specificity" "Detected in all" "HPA051758, HPA052623" Approved Supported Centrosome,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Centrosome Cytosol "HPA051758: , HPA052623: AB_2681888" "unprognostic (8.09e-3)" "unprognostic (5.38e-2)" "unprognostic (2.40e-2)" "unprognostic (1.31e-2)" "unprognostic (5.60e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (1.06e-1)" "unprognostic (1.14e-1)" "unprognostic (2.28e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (9.37e-8)" "unprognostic (1.67e-1)" "unprognostic (2.04e-1)" "unprognostic (3.04e-1)" "unprognostic (2.09e-1)" 125.3 170.2 161.7 59.9 150.5 159.3 130.6 131.7 284.6 169.3 145.5 174.2 79.5 140.6 18.2 164.8 162.4 16.4 401.3 150.5 141.8 143.8 199.5 86.3 60.3 150.0 142.2 190.3 250.9 49.3 117.1 32.9 133.9 144.2 19.6 11.4 172.6 41.2 202.4 147.1 102.8 20.4 133.4 103.6 160.7 195.1 157.4 48.1 159.0 29.9 25.5 131.8 143.1 151.4 462.9 239.6 38.6 173.1 20.7 49.8 190.5 203.1 56.7 72.2 59.6 384.0 168.3 251.5 288.1 39.5 47.2 223.4 19.7 68.9 11.2 376.3 667.0 132.8 313.5 485.9 71.5 155.1 97.1 65.7 77.6 45.4 26.9 58.4 80.6 251.8 189.6 268.9 35.8 572.5 336.0 962.4 137.8 85.7 435.8 447.0 105.4 626.6 55.3 140.2 304.7 377.8 121.3 201.1 369.8 15.1 218.5 374.8 164.7 199.8 354.7 155.3 203.4 378.1 257.5 257.9 244.6 203.3 133.3 0.4 19.9 83.0 18.6 21.5 16.5 37.6 25.5 24.7 25.4 38.5 29.1 24.2 10.7 27.3 20.4 48.1 21.3 12.2 161.7 150.5 131.7 284.6 150.5 141.8 150.0 142.2 133.9 133.4 157.4 151.4 240.2 41.7 29.4 20.5 253.6 297.2 321.4 193.4 248.2 175.2 543.9 739.1 326.5 243.1 104.6 242.8 43.8 282.8 238.0 378.4 467.6 358.4 327.3 115.5 326.7 210.0 173.0 308.2 21.7 591.7 466.6 250.1 166.7 171.7 50.8 484.6 250.2 363.5 342.0 131.2 22.8 453.0 99.7 232.7 365.6 1258.6 249.8 202.4 268.6 14.0 179.7 358.3 150.4 16.6 24.5 584.9 281.6 143.7 278.7 375.9 181.7 801.3 61.7 110.6 164.3 169.1 277.3 165.4 183.3 418.2 377.2 165.1 282.3 338.4 360.7 358.0 TUBA3E ENSG00000152086 "Tubulin alpha 3e" Q6PEY2 2 130191745-130198439 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 29 "heart muscle: 53.3;testis: 175.3" "Group enriched" "Detected in some" 6 "Early spermatids: 259.8;Late spermatids: 109.4;Spermatocytes: 415.4;Spermatogonia: 172.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 4.2;U-2 OS: 2.7" "HPA039247, HPA043684, HPA063394" Uncertain Supported Microtubules NA NA "Cluster 43: Testis - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Microtubules "HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (1.02e-3)" "unprognostic (2.79e-1)" "unprognostic (3.73e-2)" "unprognostic (1.51e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (6.81e-3)" "unprognostic (1.33e-1)" "unprognostic (3.21e-1)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (7.89e-2)" "unprognostic (2.65e-7)" "unprognostic (1.39e-1)" "unprognostic (2.10e-1)" "unprognostic (2.02e-3)" "unprognostic (8.94e-3)" 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.4 0.1 1.7 0.0 0.0 0.0 3.9 0.4 0.0 2.5 0.0 53.3 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 175.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 259.8 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 109.4 9.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 39.5 0.0 0.1 415.4 172.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Vesicles "HPA034598: AB_10601697" "prognostic favorable (7.59e-4)" "unprognostic (1.28e-2)" "unprognostic (1.10e-3)" "unprognostic (6.80e-3)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (8.13e-3)" "unprognostic (2.63e-1)" "unprognostic (4.29e-1)" "unprognostic (2.87e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-2)" "unprognostic (2.16e-1)" "unprognostic (3.16e-2)" 27.8 25.1 25.3 18.0 25.8 24.8 25.4 26.4 28.0 33.7 21.7 25.3 21.2 29.5 32.3 31.1 29.9 19.9 18.4 25.2 26.6 29.8 17.8 26.6 29.8 26.8 25.3 41.6 20.2 40.2 22.9 13.8 26.3 24.0 19.3 15.8 29.1 27.7 12.9 39.3 24.2 17.7 26.1 26.1 24.1 10.4 25.4 23.3 30.3 12.3 26.0 26.8 28.1 27.5 22.5 10.5 13.3 8.1 27.2 30.7 16.3 10.5 28.2 22.4 26.1 24.4 48.5 25.7 36.6 18.3 11.4 20.7 10.8 19.2 16.1 33.4 20.2 20.2 5.4 27.3 22.7 20.8 40.2 26.2 44.2 14.6 8.1 21.8 23.7 24.3 19.8 22.6 27.7 20.7 38.5 37.5 17.2 11.2 26.4 29.4 14.2 24.1 18.8 18.6 12.4 22.8 12.3 22.4 24.2 8.7 24.5 25.3 18.6 10.1 10.4 18.5 8.3 12.4 13.0 19.7 22.9 22.1 13.5 129.9 94.6 154.8 80.8 136.0 71.8 96.3 85.1 85.8 95.2 98.9 81.1 74.8 33.3 80.6 174.9 73.8 103.6 132.8 25.3 25.8 26.4 28.0 25.2 26.6 26.8 25.3 26.3 26.1 25.4 27.5 37.5 19.2 28.3 3.6 43.6 51.9 42.3 104.2 40.5 25.9 43.3 41.9 13.9 35.8 50.8 77.3 10.4 76.7 35.1 29.9 105.7 47.4 1.4 14.5 16.9 30.8 27.6 13.5 8.7 42.7 36.6 30.6 21.4 20.3 53.3 22.7 33.2 21.4 63.5 23.5 12.3 35.6 99.7 45.5 60.7 4.5 42.6 49.4 53.4 5.6 97.3 48.4 49.4 10.1 12.2 27.5 49.1 52.3 16.9 14.9 51.9 65.9 24.3 27.6 46.0 29.2 31.7 9.0 24.0 42.4 70.0 26.4 51.3 39.1 41.6 30.0 IMP4 "BXDC4, MGC19606" ENSG00000136718 "IMP U3 small nucleolar ribonucleoprotein 4" Q96G21 2 130342877-130347967 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 303.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066222, HPA066673" Enhanced Nucleoli NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli "HPA066222: AB_2685638, HPA066673: AB_2685701" "unprognostic (8.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-1)" "unprognostic (3.70e-3)" "unprognostic (2.18e-3)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.28e-2)" "unprognostic (5.08e-2)" "unprognostic (4.47e-2)" "unprognostic (1.09e-1)" "unprognostic (6.10e-2)" 29.2 25.4 14.3 20.6 16.1 20.8 25.6 15.3 16.8 14.8 11.4 22.4 19.9 18.0 6.3 20.5 13.9 12.4 37.5 13.7 16.5 19.9 47.7 17.7 24.5 18.5 18.3 12.1 45.4 12.9 11.4 11.5 16.6 15.4 7.2 3.6 31.8 12.0 70.1 18.7 18.5 11.7 15.9 17.3 24.5 11.8 18.1 7.2 11.4 25.5 12.2 23.3 15.7 16.9 88.7 87.1 11.1 59.2 13.5 22.7 61.5 60.8 30.2 54.1 39.8 184.5 55.0 303.2 71.5 30.2 36.0 56.6 64.5 66.5 25.9 64.2 66.0 100.3 33.2 143.8 70.7 99.7 51.8 28.1 48.0 71.9 37.6 10.9 38.5 68.7 103.1 58.8 26.5 157.0 63.2 57.1 85.4 53.0 106.3 73.1 39.4 134.4 27.0 61.0 57.9 51.8 41.3 124.0 62.9 7.2 52.7 47.0 47.5 69.8 74.3 75.2 109.0 77.5 87.8 235.4 56.5 56.5 98.9 12.3 72.7 23.9 71.5 82.6 66.1 115.9 62.7 62.6 84.1 99.7 64.8 64.6 8.0 90.8 79.4 91.5 68.9 89.2 14.3 16.1 15.3 16.8 13.7 16.5 18.5 18.3 16.6 15.9 18.1 16.9 41.4 16.0 24.8 3.3 65.5 106.6 79.3 67.0 58.6 21.9 49.5 46.4 53.7 58.6 46.5 44.1 4.2 63.6 52.3 43.4 101.8 96.4 24.2 19.6 27.3 48.6 54.5 32.6 4.2 110.3 100.5 43.2 45.9 22.3 46.3 26.8 29.6 89.1 76.5 16.8 4.8 49.8 52.9 36.5 54.0 69.9 30.7 37.5 78.2 1.0 66.1 18.9 33.0 4.5 5.0 83.7 54.2 25.6 82.4 148.6 55.5 144.6 22.9 25.5 26.3 43.7 51.6 32.7 48.3 57.6 110.4 49.3 45.9 62.1 77.5 79.2 PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase non-receptor type 18" Q99952 2 130356045-130375405 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 143.4;NK-cells: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 63.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Intermediate filaments" "CAB012174: AB_2173224, HPA053367: AB_2732579" "unprognostic (3.11e-3)" "unprognostic (2.89e-3)" "unprognostic (1.67e-3)" "unprognostic (1.73e-3)" "unprognostic (5.81e-3)" "unprognostic (3.08e-3)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (4.65e-1)" "unprognostic (2.10e-2)" "unprognostic (7.33e-2)" "unprognostic (5.65e-2)" "unprognostic (4.52e-2)" "unprognostic (1.00e-2)" "unprognostic (3.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.85e-3)" 22.3 12.3 19.6 23.2 19.4 28.2 21.5 21.7 21.4 21.2 18.4 35.3 21.7 15.7 6.1 17.8 19.6 14.8 15.3 18.8 19.1 25.4 37.8 22.0 42.7 21.0 19.6 12.5 34.6 9.5 19.0 12.2 20.1 33.3 24.7 6.4 31.9 13.2 7.5 12.7 39.4 13.3 18.7 63.8 27.0 4.6 20.0 11.1 20.0 7.5 48.6 18.8 18.9 19.6 12.4 8.3 3.2 16.2 19.7 13.5 32.9 6.2 5.6 7.9 8.8 16.4 18.5 46.4 6.2 15.2 3.7 13.8 14.3 14.1 7.6 21.1 8.0 16.9 9.8 19.5 10.2 16.6 44.5 16.0 11.4 8.7 12.0 1.7 15.2 10.1 16.1 34.2 15.4 24.3 3.1 28.4 3.3 26.6 8.6 28.4 9.5 63.0 15.9 7.5 20.6 5.4 10.9 38.6 18.7 3.1 13.2 24.1 14.4 11.2 12.6 6.2 5.9 5.6 1.6 44.5 17.1 14.9 12.4 8.4 7.8 6.7 6.4 11.2 4.0 7.3 4.2 6.1 6.9 5.1 2.6 5.1 4.8 3.1 19.4 7.5 6.0 10.7 19.6 19.4 21.7 21.4 18.8 19.1 21.0 19.6 20.1 18.7 20.0 19.6 37.2 28.9 23.9 12.1 43.6 6.5 28.8 15.9 12.0 13.4 52.0 53.5 9.0 18.6 17.5 36.8 4.2 15.6 85.6 75.9 54.8 19.0 0.9 20.6 14.0 30.7 48.6 32.4 18.2 45.4 30.5 16.3 65.2 24.0 35.5 12.2 25.7 21.1 92.4 10.1 18.6 52.5 30.5 113.6 35.9 1.6 19.0 143.4 33.8 35.6 65.2 18.4 148.3 5.5 6.1 29.0 66.9 11.3 23.5 37.9 41.3 37.3 20.5 11.6 19.7 15.1 21.5 2.6 6.0 19.4 5.8 11.5 39.3 16.2 47.5 28.9 POTEI POTE2beta ENSG00000196834 "POTE ankyrin domain family member I" P0CG38 2 130459455-130509707 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.2;prostate: 2.5;testis: 3.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 2.3;Breast myoepithelial cells: 1.5;Cardiomyocytes: 1.9;Prostatic glandular cells: 1.9;Spermatocytes: 5.8;Spermatogonia: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;BEWO: 1.4;K-562: 2.0;MCF7: 1.2;RPMI-8226: 1.2;U-2 OS: 3.7;U-266/70: 1.2" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (2.52e-3)" "unprognostic (3.08e-1)" "unprognostic (3.49e-2)" "unprognostic (9.61e-2)" "unprognostic (1.56e-2)" "unprognostic (1.62e-1)" "unprognostic (3.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.37e-1)" "unprognostic (2.99e-1)" "unprognostic (8.59e-2)" "unprognostic (2.67e-1)" "unprognostic (2.22e-3)" "unprognostic (5.52e-2)" "unprognostic (1.47e-1)" "unprognostic (3.38e-2)" 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.2 1.0 0.0 0.0 0.0 0.0 1.7 0.8 0.0 0.1 0.0 0.1 0.1 0.6 2.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.0 0.2 3.3 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 1.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.0 1.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.3 0.5 0.0 0.0 0.0 3.7 0.1 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.1 0.2 1.0 1.7 0.8 0.6 3.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.3 1.5 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.9 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.1 0.7 0.0 0.0 0.0 0.2 5.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 CFC1B ENSG00000152093 "Cripto, FRL-1, cryptic family 1B" P0CG36 2 130521197-130528604 "Predicted secreted proteins" Gastrulation "Developmental protein" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pituitary gland: 2.4" "Cell type enriched" "Detected in single" 9 "Bipolar cells: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041773 Approved "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 56: Bipolar cells - Visual perception" "HPA041773: AB_2677664" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 2.4 0.0 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CFC1 "CRYPTIC, HTX2" ENSG00000136698 "Cripto, FRL-1, cryptic family 1" P0CG37 2 130592165-130599575 "Disease related genes, Human disease related genes, Predicted secreted proteins" Gastrulation "Developmental protein" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 24.0;pancreas: 30.7;pituitary gland: 59.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 14.9;Enteroendocrine cells: 20.5" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 4.3" "Region enhanced" "Detected in all" "hypothalamus: 24.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "RPMI-8226: 12.1;SCLC-21H: 6.7;SuSa: 4.0" HPA041773 Uncertain "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA041773: AB_2677664" "unprognostic (6.65e-2)" "unprognostic (2.19e-3)" "unprognostic (1.11e-3)" "unprognostic (2.01e-1)" 1.7 0.6 4.6 0.0 2.3 0.0 0.0 2.9 3.5 0.1 0.0 0.2 0.0 0.2 0.1 0.0 1.5 0.0 1.9 1.3 24.0 0.0 0.0 0.1 0.0 3.9 8.1 0.0 30.7 0.0 59.3 0.0 5.6 7.2 0.1 3.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 10.7 0.6 8.6 5.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 2.3 2.9 3.5 1.3 24.0 3.9 8.1 5.6 3.9 8.6 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 20.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 1.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POTEJ POTE2beta ENSG00000222038 "POTE ankyrin domain family member J" P0CG39 2 130611440-130658037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Spermatocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 66: Spermatocytes - Spermatogenesis" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (8.11e-2)" "unprognostic (6.24e-2)" "unprognostic (3.19e-1)" "unprognostic (3.55e-1)" "unprognostic (3.35e-1)" "unprognostic (2.07e-2)" "unprognostic (5.44e-2)" "unprognostic (1.90e-1)" "unprognostic (2.18e-1)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.59e-2)" "unprognostic (1.18e-2)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (3.30e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMER3 "FAM123C, FLJ38377" ENSG00000178171 "APC membrane recruitment protein 3" Q8N944 2 130755540-130768134 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 14.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 8.2;Enteroendocrine cells: 15.1;Excitatory neurons: 6.6;Horizontal cells: 3.3;Inhibitory neurons: 5.7;Rod photoreceptor cells: 4.9" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 9.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA045593, HPA054230" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA045593: AB_10965021, HPA054230: AB_2682423" "unprognostic (6.68e-2)" "unprognostic (3.73e-1)" "unprognostic (2.17e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-1)" "unprognostic (5.33e-3)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (6.46e-3)" 0.0 0.6 4.0 0.0 4.5 0.1 0.0 14.6 8.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.2 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.9 0.0 2.8 0.0 1.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 4.5 14.6 8.1 3.7 3.2 1.2 0.2 1.0 0.0 1.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 15.1 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.7 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARHGEF4 "ASEF, KIAA1112, STM6" ENSG00000136002 "Rho guanine nucleotide exchange factor 4" Q9NR80 2 130836914-131047263 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.3;skin 1: 39.8" "Cell type enhanced" "Detected in many" "Astrocytes: 333.3;Excitatory neurons: 83.0;Inhibitory neurons: 83.5;Oligodendrocyte precursor cells: 143.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 12 "dendritic cells: 1.0;T-cells: 1.4" "Cell line enhanced" "Detected in many" "HaCaT: 39.9;hTCEpi: 78.9;REH: 20.3;SCLC-21H: 52.9" HPA018267 Approved NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA018267: AB_1845006" "unprognostic (2.30e-3)" "unprognostic (8.84e-2)" "unprognostic (5.32e-2)" "unprognostic (1.18e-2)" "unprognostic (4.44e-1)" "unprognostic (2.60e-2)" "unprognostic (4.69e-2)" "unprognostic (2.14e-2)" "unprognostic (8.97e-2)" "unprognostic (1.29e-1)" "unprognostic (7.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.75e-1)" "unprognostic (4.68e-2)" "prognostic favorable (7.00e-4)" "unprognostic (3.93e-3)" "unprognostic (9.71e-3)" 5.6 5.0 53.1 1.0 56.8 0.0 2.1 32.5 67.3 11.2 27.3 7.0 0.2 2.9 1.6 34.0 8.4 2.9 1.4 63.1 38.1 0.4 0.9 3.1 0.3 44.4 39.7 7.8 17.9 2.5 15.4 0.2 39.9 5.2 0.8 10.2 5.7 9.3 9.0 39.8 1.3 4.1 41.5 0.2 3.1 5.2 44.6 1.8 6.1 2.6 2.5 4.5 19.9 46.0 4.8 2.0 0.9 16.6 0.1 0.0 0.4 5.3 0.3 0.3 0.2 0.9 1.5 0.0 0.5 2.1 3.6 39.9 2.4 10.5 0.0 0.0 2.2 0.0 7.0 0.0 0.6 0.0 0.1 0.0 78.9 1.2 5.8 0.1 0.1 0.1 0.0 0.0 0.0 2.5 0.0 0.0 5.8 0.7 7.2 20.3 0.2 0.8 3.2 0.1 52.9 7.0 0.8 8.3 0.6 1.6 0.5 0.5 0.0 0.0 0.3 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.5 0.0 0.0 0.5 1.4 0.0 0.0 0.0 1.0 0.5 0.1 53.1 56.8 32.5 67.3 63.1 38.1 44.4 39.7 39.9 41.5 44.6 46.0 0.1 25.6 0.0 333.3 0.0 17.3 1.2 4.8 15.4 18.8 0.9 5.5 3.2 1.5 2.9 0.0 37.5 1.0 2.9 0.3 0.0 0.8 10.9 7.5 1.0 0.5 0.0 2.7 83.0 0.0 0.3 3.5 2.6 5.4 0.0 3.1 0.7 0.4 0.4 28.6 83.5 0.9 0.0 0.6 2.4 8.2 5.0 0.3 5.4 11.2 0.7 3.7 0.0 143.7 28.3 1.5 0.0 10.9 0.0 1.2 0.3 0.9 6.6 13.9 0.0 3.1 1.1 1.1 4.2 17.4 19.9 0.3 0.8 0.4 0.4 0.8 SMIM39 ENSG00000284479 "Small integral membrane protein 39" A0A1B0GW54 2 131035092-131035262 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "brain: 5.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.0;HEK 293: 1.5" "Not detected" "Not detected" NA NA "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" 1.2 0.1 2.2 0.0 3.4 0.0 0.1 0.0 4.2 0.3 0.5 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.1 5.0 4.2 0.1 0.0 0.1 0.0 4.2 1.6 0.2 0.1 0.0 0.1 0.0 5.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 1.1 0.0 0.1 0.1 3.2 0.0 0.2 0.0 0.0 0.0 0.1 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 0.0 4.2 5.0 4.2 4.2 1.6 5.1 1.1 3.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM168B "KIAA0280L, MANI" ENSG00000152102 "Family with sequence similarity 168 member B" A1KXE4 2 131047876-131093460 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043778, HPA061659" Enhanced NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA043778: AB_10964889, HPA061659: AB_2684577" "unprognostic (8.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.61e-1)" "unprognostic (3.26e-2)" "unprognostic (4.58e-2)" "unprognostic (6.90e-3)" "unprognostic (1.60e-2)" "unprognostic (2.10e-1)" "unprognostic (5.91e-2)" "unprognostic (1.88e-1)" "unprognostic (4.84e-2)" "unprognostic (1.88e-1)" "prognostic favorable (5.30e-5)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.30e-2)" "unprognostic (3.35e-3)" 41.5 33.7 55.5 26.8 67.7 46.2 32.1 49.8 60.1 35.4 32.6 54.2 26.3 51.4 26.5 34.4 37.9 23.7 43.4 57.5 52.1 38.4 30.9 27.6 27.8 51.4 53.6 46.9 30.1 46.7 20.3 29.4 54.0 37.5 31.9 48.6 28.1 46.8 69.9 29.9 34.3 40.8 54.7 24.2 36.3 26.8 60.1 38.5 36.2 52.9 31.3 47.6 28.0 55.8 74.1 47.6 98.2 67.7 82.2 62.4 74.0 75.2 54.9 46.3 39.7 88.1 40.0 78.6 61.1 79.8 31.8 57.1 83.8 83.8 66.2 64.8 62.3 72.1 49.8 67.4 83.0 84.8 58.6 63.6 82.4 94.5 81.0 62.3 65.5 72.3 70.3 28.9 72.2 53.4 68.0 55.3 61.6 60.2 57.5 85.0 82.5 70.2 63.7 84.0 71.3 100.0 58.2 58.8 80.1 46.0 52.4 79.2 70.8 77.3 78.9 58.0 73.9 67.9 81.2 98.1 65.9 49.3 70.7 2.5 2.2 4.3 4.4 1.5 4.0 3.0 3.6 3.7 2.0 3.0 4.7 3.4 2.1 2.5 3.4 3.3 3.2 2.8 55.5 67.7 49.8 60.1 57.5 52.1 51.4 53.6 54.0 54.7 60.1 55.8 24.4 35.3 27.4 25.1 19.0 22.8 18.3 24.5 16.5 32.2 28.6 23.6 51.4 24.3 21.6 35.0 37.5 27.0 22.5 38.8 5.9 24.8 12.3 28.0 21.6 22.8 31.8 13.3 47.9 30.8 24.8 23.8 19.4 29.0 19.0 34.7 22.1 39.8 20.1 30.3 52.2 29.8 14.2 25.1 16.0 11.1 29.2 19.2 24.9 28.1 20.9 27.0 14.4 18.6 38.8 38.0 25.3 49.7 25.1 33.3 27.3 26.8 19.5 42.3 13.1 27.5 27.4 18.2 22.8 20.0 25.1 38.3 19.0 23.2 36.7 31.0 PLEKHB2 "EVT2, FLJ20783" ENSG00000115762 "Pleckstrin homology domain containing B2" Q96CS7 2 131104847-131353709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075014 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 44: Endometrium - Transcription" "HPA075014: AB_2732275" "unprognostic (1.99e-2)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "unprognostic (8.78e-2)" "unprognostic (5.18e-3)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (9.33e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (4.05e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.72e-8)" "unprognostic (1.28e-2)" "unprognostic (1.03e-1)" "unprognostic (1.14e-2)" "unprognostic (2.65e-1)" 27.0 55.5 52.7 38.3 55.4 64.8 26.1 61.4 56.2 25.4 53.4 59.9 46.8 16.6 30.7 30.3 26.7 29.7 33.5 57.8 73.1 111.8 22.4 44.4 37.0 64.8 69.4 11.7 20.8 88.5 26.2 31.0 81.3 34.6 60.9 81.1 26.0 26.3 35.6 23.5 56.2 25.9 56.8 42.5 58.5 36.1 60.0 31.2 48.7 30.6 34.5 38.3 18.2 63.1 85.3 65.4 48.6 38.1 37.4 36.2 79.2 94.4 80.0 88.9 73.8 140.0 83.4 68.2 97.5 92.0 64.4 58.8 89.0 81.5 98.8 40.0 48.6 119.4 31.0 81.4 51.9 115.4 88.8 31.9 67.2 105.2 96.9 54.6 71.1 36.5 57.5 53.0 166.9 46.7 71.4 57.0 73.9 80.8 99.1 52.5 37.7 72.7 138.6 89.7 60.3 39.7 29.6 166.3 107.6 64.9 23.6 89.0 86.6 89.2 60.4 76.7 86.5 51.2 85.6 46.5 130.8 76.6 82.8 27.5 54.9 29.0 24.4 69.2 23.9 15.5 18.2 23.2 52.7 17.1 19.4 23.2 32.3 26.5 78.2 18.7 23.6 48.3 52.7 55.4 61.4 56.2 57.8 73.1 64.8 69.4 81.3 56.8 60.0 63.1 37.8 60.9 53.9 14.4 50.0 114.3 35.6 47.2 64.9 85.6 57.6 26.5 28.6 34.3 59.5 64.4 125.1 44.9 59.5 174.4 158.5 62.4 66.4 108.8 44.2 57.2 56.8 44.2 38.9 43.1 51.0 29.6 62.2 164.1 58.9 25.4 31.4 20.9 106.3 101.0 41.5 67.6 128.1 111.0 169.5 22.1 14.3 117.9 76.5 26.2 86.2 46.0 49.4 15.1 32.0 81.5 68.4 24.0 35.8 58.6 120.2 193.4 52.1 78.8 13.1 26.1 35.9 92.3 65.9 97.6 140.4 92.9 59.1 51.0 76.1 70.7 POTEE "A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma" ENSG00000188219 "POTE ankyrin domain family member E" Q6S8J3 2 131218067-131265278 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 1.9;testis: 1.4" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 6.0;Breast glandular cells: 2.5;Prostatic glandular cells: 2.8;Smooth muscle cells: 2.4;Spermatocytes: 4.9;Spermatogonia: 2.0;Urothelial cells: 2.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.2;K-562: 1.4;U-2 OS: 2.3" "HPA041264, HPA041271, HPA043260" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "HPA041264: AB_2677383, HPA041271: AB_2677386, HPA043260: AB_2678396" "unprognostic (3.13e-2)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" "unprognostic (2.59e-3)" "unprognostic (3.84e-2)" "unprognostic (1.05e-1)" "unprognostic (6.61e-3)" "unprognostic (5.77e-2)" "unprognostic (7.60e-2)" "unprognostic (7.46e-3)" "unprognostic (1.19e-1)" "unprognostic (1.84e-1)" "unprognostic (1.72e-1)" "unprognostic (1.90e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.1 0.5 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.1 0.2 1.1 0.5 0.4 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.0 0.2 0.0 0.0 2.5 1.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.8 0.0 0.7 0.2 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.1 0.0 0.0 0.0 0.1 2.4 4.9 2.0 0.0 0.1 0.4 0.1 0.2 0.0 2.2 RAB6D "RAB6CL, WTH3DI" ENSG00000233087 "RAB6D, member RAS oncogene family" Q53S08 2 131361111-131364142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "parathyroid gland: 7.4" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Cancer enhanced" "Detected in some" "prostate cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MOLT-4: 2.2" HPA059131 Uncertain Approved "Golgi apparatus" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "HPA059131: AB_2683916" "unprognostic (4.19e-2)" "unprognostic (8.54e-2)" "unprognostic (1.16e-1)" "unprognostic (3.03e-2)" "unprognostic (4.08e-1)" "unprognostic (4.79e-2)" "unprognostic (4.41e-2)" "unprognostic (1.01e-1)" "unprognostic (1.87e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-1)" "unprognostic (2.55e-2)" "unprognostic (2.61e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.12e-1)" 0.0 0.2 0.6 0.1 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.9 0.2 0.1 0.3 0.0 0.1 0.2 0.0 0.6 0.9 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 7.4 0.0 0.0 0.5 1.4 0.8 0.1 0.0 0.0 0.0 0.0 0.7 0.2 0.2 0.0 0.0 1.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.2 0.0 0.3 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.8 0.6 0.9 0.3 0.2 0.5 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MZT2A "FAM128A, MOZART2A" ENSG00000173272 "Mitotic spindle organizing protein 2A" Q6P582 2 131464900-131492743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 252.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 79.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 421.1" "HPA051758, HPA052623" Approved Supported Centrosome,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Centrosome Cytosol "HPA051758: , HPA052623: AB_2681888" "prognostic favorable (3.04e-4)" "unprognostic (3.82e-2)" "unprognostic (7.14e-2)" "unprognostic (1.78e-1)" "unprognostic (5.39e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-2)" "unprognostic (2.44e-2)" "unprognostic (6.47e-2)" "unprognostic (3.55e-2)" "unprognostic (2.16e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (3.04e-11)" "unprognostic (1.51e-2)" "unprognostic (5.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" 41.7 68.6 31.8 11.6 28.4 40.5 44.4 16.1 74.7 82.9 23.9 59.7 31.8 60.7 2.5 102.7 85.8 6.6 252.2 32.6 24.5 50.8 81.1 28.3 19.2 22.5 23.1 87.9 94.7 14.4 38.2 4.7 24.8 74.4 2.6 0.7 52.6 9.1 48.0 54.5 45.8 2.1 15.3 37.8 64.8 36.8 27.7 7.2 55.0 5.6 4.2 55.1 69.8 23.9 212.0 115.2 3.0 40.9 3.3 7.7 44.1 70.6 17.3 27.8 28.2 286.2 71.3 136.7 88.3 3.4 2.8 94.6 7.2 49.8 1.0 54.5 346.6 56.8 135.3 353.8 17.3 100.7 20.4 22.3 27.8 18.7 8.8 6.4 23.8 122.7 114.1 138.7 6.9 196.1 137.1 421.1 73.0 28.1 259.8 114.5 37.3 317.5 18.7 102.2 160.1 20.4 71.6 46.5 135.2 2.1 74.7 177.8 61.6 70.2 168.9 28.3 68.6 128.9 105.6 116.9 97.2 64.3 41.3 22.1 2.0 79.5 8.5 1.4 9.4 32.4 18.9 10.9 7.7 18.8 20.7 10.2 1.1 7.1 0.8 12.0 21.7 4.9 31.8 28.4 16.1 74.7 32.6 24.5 22.5 23.1 24.8 15.3 27.7 23.9 60.4 16.0 13.8 11.8 126.6 148.1 138.9 81.9 124.1 55.6 196.7 284.6 305.6 111.5 47.3 71.7 20.9 88.7 101.1 159.7 170.2 210.3 25.5 42.2 89.7 68.7 108.8 75.7 15.8 167.8 223.9 100.4 115.2 70.4 23.6 189.2 99.2 128.0 123.1 26.9 16.4 240.7 54.9 79.4 138.1 89.8 152.8 71.4 103.2 4.7 105.2 112.9 114.4 10.1 13.0 269.2 167.0 205.4 140.8 163.1 240.1 255.6 28.9 41.9 92.1 83.2 85.9 44.4 166.3 269.5 142.9 42.4 155.8 156.7 270.4 133.6 TUBA3D H2-ALPHA ENSG00000075886 "Tubulin alpha 3d" P0DPH8 2 131476119-131482934 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "heart muscle: 86.2;testis: 220.2" "Cell type enhanced" "Detected in some" "Early spermatids: 358.9;Late spermatids: 119.6;Spermatocytes: 667.9;Spermatogonia: 326.1" "Cancer enhanced" "Detected in many" "testis cancer: 7.6" "Region enhanced" "Detected in single" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NB-4: 1.1" "Not detected" "Not detected" "CAB004972, HPA039247, HPA043684, HPA063394" Uncertain Supported Microtubules NA NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Microtubules "CAB004972: AB_425727, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "prognostic favorable (4.65e-4)" "unprognostic (6.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-3)" "unprognostic (1.82e-1)" "unprognostic (1.50e-3)" "unprognostic (2.17e-1)" "unprognostic (2.06e-2)" "unprognostic (1.39e-1)" "unprognostic (2.89e-1)" "unprognostic (1.08e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (4.75e-9)" "unprognostic (4.60e-2)" "unprognostic (2.28e-1)" "unprognostic (9.96e-4)" "unprognostic (2.28e-1)" 0.1 0.1 0.4 0.2 0.3 0.4 0.6 1.6 0.4 2.8 0.0 0.1 0.1 4.8 6.8 0.2 4.0 0.2 86.2 0.6 0.2 0.1 0.4 0.1 0.4 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.0 10.1 0.0 0.3 0.3 0.4 0.1 0.6 0.2 0.3 0.0 0.2 0.2 220.2 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.5 0.2 0.2 0.9 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.7 0.1 0.6 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.3 0.0 0.5 0.5 1.1 0.7 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.5 0.1 0.2 0.0 0.0 0.2 0.1 0.0 0.2 0.3 0.4 0.5 0.3 0.1 0.2 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.6 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.4 36.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.9 0.4 1.1 1.2 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.1 0.0 0.4 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 119.6 12.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 4.8 0.0 0.0 0.0 0.0 52.6 0.0 0.1 667.9 326.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 ANKRD30BL "ANKRD30BP3, NCRNA00164" ENSG00000163046 "Ankyrin repeat domain 30B like" A7E2S9 2 132147591-132257969 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 21 "testis: 3.4" "Group enriched" "Detected in some" 4 "Excitatory neurons: 239.7;Inhibitory neurons: 229.8;Oligodendrocyte precursor cells: 73.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 21 "REH: 2.0" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.67e-1)" "unprognostic (1.42e-1)" "unprognostic (5.57e-2)" "unprognostic (2.15e-1)" "unprognostic (2.99e-1)" "unprognostic (2.17e-1)" "unprognostic (1.42e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.1 0.0 0.0 0.0 239.7 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 229.8 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 3.7 0.0 0.2 0.0 73.9 6.9 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 42.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 12.1;Early spermatids: 20.6;Late spermatids: 19.4;Oligodendrocyte precursor cells: 18.6;Spermatocytes: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "A-431: 32.0;CAPAN-2: 26.9;hTEC/SVTERT24-B: 30.8;RT4: 27.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" 0.2 0.0 0.7 0.9 0.7 0.0 2.1 0.5 0.7 4.4 1.3 6.8 4.6 0.4 0.8 0.8 3.6 2.2 0.0 0.4 0.7 2.6 3.3 3.9 0.0 1.6 2.2 0.0 3.9 5.1 0.1 0.1 2.0 0.5 5.7 0.0 0.5 1.0 0.0 1.0 3.7 0.3 1.2 0.0 6.1 0.2 0.7 0.0 1.3 0.0 0.2 2.6 0.6 0.2 32.0 18.1 0.3 0.0 0.5 3.6 0.0 2.8 11.1 5.8 3.3 17.7 26.9 0.0 9.7 1.9 13.1 18.6 0.0 12.9 5.7 0.1 0.0 0.0 1.9 0.7 0.6 0.0 0.0 1.1 9.7 30.8 3.1 7.0 0.1 0.0 0.0 0.0 4.2 3.0 0.0 0.0 0.3 7.3 10.5 0.0 0.5 0.0 21.2 27.9 0.0 0.1 2.0 10.3 0.1 1.1 5.8 0.0 5.6 12.4 12.2 4.2 16.8 0.0 0.0 0.1 18.9 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.7 0.5 0.7 0.4 0.7 1.6 2.2 2.0 1.2 0.7 0.2 0.0 16.0 8.7 12.1 0.0 0.1 0.7 2.4 0.0 0.2 1.5 0.9 0.2 2.8 6.7 0.0 0.0 0.0 2.7 10.3 0.0 5.6 20.6 2.6 0.2 0.1 2.4 0.0 3.9 3.1 0.0 0.2 4.1 1.8 0.0 0.0 0.0 3.6 0.0 0.0 4.9 1.6 0.0 0.6 0.3 19.4 0.3 0.3 0.0 1.0 0.6 1.4 0.0 18.6 1.8 5.9 3.0 0.4 0.1 0.3 1.9 0.7 6.1 0.0 0.0 0.1 0.3 32.4 1.2 0.5 0.0 0.0 0.0 0.0 4.9 1.2 LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.2;choroid plexus: 15.4;fallopian tube: 53.5;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Ductal cells: 73.8;Exocrine glandular cells: 74.5;monocytes: 62.0;Oligodendrocyte precursor cells: 28.1;Pancreatic endocrine cells: 43.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 41.6;HUVEC TERT2: 32.7;SK-MEL-30: 36.5;U-251 MG: 65.9;WM-115: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Vesicles, Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" 0.6 0.8 24.8 0.3 27.1 0.4 0.8 19.5 25.5 0.3 15.4 8.1 0.1 0.9 0.1 1.5 53.5 1.2 0.8 24.2 29.2 5.9 1.0 1.0 0.6 29.9 30.0 1.3 5.1 0.3 33.7 0.0 27.7 0.7 0.2 1.6 5.5 0.1 0.3 0.3 1.6 0.6 27.3 0.3 0.9 0.7 31.2 2.2 0.9 0.1 1.0 0.8 0.6 21.5 0.4 8.6 11.6 0.2 0.0 0.0 0.0 1.9 1.5 6.3 1.4 0.6 1.1 0.0 18.3 5.1 3.0 7.2 0.0 0.0 2.9 0.1 1.8 0.0 4.0 0.0 0.0 0.0 0.2 0.0 0.1 41.6 0.0 1.7 32.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 11.1 0.2 3.3 0.0 0.0 0.0 15.1 0.2 1.1 2.3 1.8 0.2 36.5 26.8 0.1 0.3 1.5 0.7 17.4 5.9 65.9 0.1 0.0 0.1 10.0 0.0 140.5 0.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 27.1 19.5 25.5 24.2 29.2 29.9 30.0 27.7 27.3 31.2 21.5 0.7 0.0 0.0 8.1 0.2 0.1 0.1 0.4 0.0 1.6 2.0 0.9 0.2 2.8 0.2 5.5 0.0 0.0 0.0 0.5 1.9 73.8 5.6 1.4 0.1 0.2 1.8 0.0 0.8 74.5 0.0 2.2 0.0 0.9 0.0 0.1 0.4 0.0 0.1 15.2 4.7 0.0 0.0 0.8 0.7 9.3 4.1 0.1 0.0 0.0 62.0 1.4 0.0 28.1 4.4 43.4 0.0 0.0 0.0 0.1 0.1 4.8 0.3 0.8 0.0 0.2 3.9 2.6 2.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 MGAT5 "GNT-V, MGAT5A" ENSG00000152127 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase" Q09328 2 134119983-134454621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.5;Inhibitory neurons: 134.5;Microglial cells: 141.5;Oligodendrocyte precursor cells: 124.7;Oligodendrocytes: 495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010919 Approved "Intracellular and membrane" NA NA 440000 "Cluster 37: B-cells - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA010919: AB_10601864" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.21e-2)" "unprognostic (3.65e-1)" "unprognostic (3.76e-1)" "unprognostic (4.45e-3)" "unprognostic (3.41e-3)" "unprognostic (5.68e-2)" "unprognostic (8.63e-3)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" "unprognostic (5.97e-2)" "unprognostic (1.81e-2)" "unprognostic (9.27e-2)" "unprognostic (2.17e-2)" "unprognostic (1.91e-1)" 9.4 10.4 15.4 15.0 25.2 15.5 7.9 29.6 17.9 9.1 8.5 12.6 16.1 8.8 6.6 9.0 19.0 11.1 39.0 13.3 32.1 15.3 3.7 10.4 24.6 30.5 32.9 12.0 10.9 16.3 6.2 15.1 32.1 8.4 15.0 11.6 14.6 9.4 2.2 6.8 18.1 11.2 18.4 16.2 16.9 7.2 24.2 19.1 11.3 4.6 25.4 13.2 5.0 26.4 27.9 11.0 27.3 19.7 23.8 45.3 19.1 36.4 55.0 14.4 12.0 4.7 13.4 44.3 27.1 29.2 16.4 9.7 21.6 17.0 27.3 43.9 12.7 25.0 13.7 58.0 15.5 24.5 85.1 12.5 17.4 30.3 18.6 19.6 108.7 22.1 13.0 29.6 26.3 17.9 13.3 11.6 12.5 28.9 27.0 16.2 32.3 28.6 11.1 33.7 45.1 55.4 11.7 9.9 69.3 18.3 7.7 16.8 49.5 45.1 24.0 33.1 19.3 8.3 4.1 16.5 37.8 34.4 73.1 0.6 0.4 1.0 0.8 0.3 1.3 3.0 1.5 1.0 0.3 3.7 0.6 0.8 1.1 1.3 0.4 0.9 1.0 0.6 15.4 25.2 29.6 17.9 13.3 32.1 30.5 32.9 32.1 18.4 24.2 26.4 13.2 3.2 2.4 66.6 63.2 8.0 5.7 10.3 8.0 43.6 11.6 9.9 67.3 8.6 8.5 1.8 2.1 3.2 14.9 36.9 0.0 9.0 15.6 22.6 7.6 12.5 7.2 4.4 109.5 9.0 26.3 9.0 37.2 21.0 0.0 23.1 11.7 3.0 15.5 16.8 134.5 20.3 30.5 13.5 9.9 15.1 4.4 12.9 14.2 141.5 5.3 11.4 9.2 124.7 495.5 13.0 13.2 9.4 9.0 9.7 17.6 2.4 22.6 5.2 0.0 8.8 14.3 0.6 6.1 7.3 7.2 5.3 22.4 16.6 9.9 14.5 TMEM163 "DKFZP566N034, SV31" ENSG00000152128 "Transmembrane protein 163" Q8TC26 2 134455759-134719000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.3;pancreas: 27.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 36.9;Excitatory neurons: 62.2;Exocrine glandular cells: 30.8;Oligodendrocyte precursor cells: 219.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 20.3;RPTEC TERT1: 67.3;SCLC-21H: 30.2;U-937: 12.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007224 Uncertain NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA007224: AB_2667780" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (7.25e-3)" "unprognostic (3.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" "unprognostic (6.08e-3)" "prognostic favorable (7.94e-4)" "unprognostic (9.05e-2)" "unprognostic (9.62e-2)" "unprognostic (6.02e-2)" "unprognostic (2.04e-1)" "unprognostic (2.60e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" "unprognostic (6.75e-3)" "prognostic favorable (3.15e-4)" 3.4 8.5 13.5 5.1 13.4 0.3 1.4 18.8 13.3 0.2 5.4 1.0 0.6 0.4 0.3 0.1 2.8 9.3 6.7 12.9 15.2 1.6 0.4 14.5 10.4 18.3 20.7 0.9 27.8 0.8 13.9 3.7 15.4 0.2 0.5 4.0 3.0 0.2 0.3 0.1 1.0 0.4 16.5 1.6 7.3 6.5 28.3 2.0 0.9 0.5 16.4 12.2 0.1 23.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.2 20.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 3.5 6.7 0.1 0.1 0.3 0.0 0.6 0.1 0.0 5.2 1.1 2.3 0.0 0.1 0.1 67.3 10.0 30.2 1.1 0.0 0.0 1.6 0.1 0.0 0.0 7.0 0.0 0.4 0.0 1.5 1.6 0.0 0.0 0.0 12.6 1.3 0.0 0.0 0.0 0.3 0.0 0.4 0.4 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.2 13.5 13.4 18.8 13.3 12.9 15.2 18.3 20.7 15.4 16.5 28.3 23.0 19.3 3.2 36.9 2.6 6.7 0.0 0.0 0.0 0.0 2.7 0.2 5.1 5.4 7.2 0.0 0.0 0.0 0.1 0.9 0.1 0.0 8.5 4.8 0.3 0.2 3.5 0.0 0.4 62.2 30.8 0.4 0.7 20.9 1.0 0.0 0.6 0.4 0.3 5.0 1.7 23.5 0.4 0.0 1.3 0.0 3.8 0.0 2.7 0.0 14.0 2.6 1.0 5.2 219.7 13.0 12.6 0.1 0.4 0.3 0.0 0.0 0.3 0.0 5.7 0.0 0.5 0.4 2.1 1.6 0.0 0.4 0.1 0.7 1.9 0.1 2.5 ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 141.1;liver: 162.5" "Group enriched" "Detected in some" 4 "Hepatocytes: 120.2;Proximal tubular cells: 408.1" "Group enriched" "Detected in some" 23 "liver cancer: 21.2;renal cancer: 19.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "RPTEC TERT1: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA 12000 "Cluster 37: B-cells - Transcription" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA010533: AB_1844517, HPA011179: AB_1844516" "unprognostic (1.06e-2)" "unprognostic (5.30e-2)" "unprognostic (1.40e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-4)" "unprognostic (7.60e-2)" "unprognostic (5.17e-2)" "unprognostic (2.44e-3)" "prognostic favorable (2.39e-4)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.93e-2)" "unprognostic (2.65e-5)" 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.9 0.3 0.0 0.0 0.1 0.9 0.1 0.0 0.0 0.0 7.1 0.2 0.0 0.3 141.1 162.5 0.1 0.3 0.8 0.2 0.7 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.4 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.6 0.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.4 0.1 1.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.8 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.6 0.0 0.0 0.3 0.8 0.3 1.2 0.2 0.5 0.1 0.6 0.3 26.7 0.4 1.0 0.3 0.1 0.3 0.4 0.8 0.2 0.7 1.0 0.0 0.4 0.2 0.8 0.2 0.1 0.5 0.2 0.3 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.9 0.3 0.0 0.3 0.8 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.9 0.2 50.1 0.0 9.2 0.0 0.0 0.0 0.0 54.8 0.2 0.0 0.0 0.1 0.0 0.0 2.7 8.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 120.2 0.0 0.0 7.3 0.0 0.0 1.9 0.0 0.0 0.0 2.8 0.0 1.0 0.0 0.0 0.0 2.5 1.9 0.1 0.0 0.0 0.0 0.0 0.0 408.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 CCNT2 ENSG00000082258 "Cyclin T2" O60583 2 134918235-134959342 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005559 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA005559: AB_1078608" "unprognostic (2.49e-2)" "unprognostic (1.19e-1)" "unprognostic (9.57e-2)" "unprognostic (1.25e-1)" "unprognostic (4.92e-2)" "unprognostic (2.65e-3)" "unprognostic (1.85e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.44e-4)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.33e-1)" "unprognostic (8.51e-2)" "unprognostic (9.94e-2)" "prognostic favorable (3.28e-4)" 13.4 12.1 10.1 12.2 10.2 29.0 15.6 13.7 12.4 16.4 10.6 13.0 13.4 13.5 14.8 12.8 14.0 9.4 11.7 9.9 10.8 10.9 18.3 14.9 15.5 10.4 10.0 17.4 19.8 15.0 15.1 12.0 10.8 13.5 12.1 19.0 13.0 10.7 10.3 15.4 14.4 8.5 11.1 15.6 14.8 12.3 10.5 14.4 14.5 9.7 14.1 15.0 16.3 14.4 9.0 4.4 28.0 10.5 13.6 13.7 21.3 12.2 9.9 11.2 13.9 11.9 10.1 14.6 8.9 10.0 5.4 11.4 17.0 9.1 16.3 7.9 11.5 15.8 11.9 16.9 13.3 14.3 13.4 12.6 17.6 11.1 13.5 14.4 16.8 10.8 13.4 14.6 13.2 6.1 16.0 21.2 22.8 7.4 9.0 15.2 10.0 11.7 17.4 24.4 19.1 15.8 8.9 10.3 14.2 20.3 10.8 17.3 15.3 14.4 15.9 6.2 9.0 10.2 6.7 15.1 9.0 11.2 12.5 3.8 1.6 2.0 1.7 2.0 2.1 1.6 1.9 2.1 2.1 1.2 3.3 2.6 2.1 2.8 1.0 1.9 2.6 1.3 10.1 10.2 13.7 12.4 9.9 10.8 10.4 10.0 10.8 11.1 10.5 14.4 27.1 25.6 26.0 49.6 38.0 15.0 28.8 17.9 26.7 34.7 21.6 15.4 23.5 14.3 21.8 14.7 33.3 11.9 35.3 22.4 7.9 16.2 5.5 20.2 30.2 21.5 18.5 20.0 73.6 14.9 9.6 23.7 46.9 33.1 11.4 31.1 18.9 20.9 10.1 42.1 70.1 16.4 6.1 15.7 22.1 14.6 14.0 25.2 8.8 52.5 23.6 12.9 19.6 76.9 81.8 14.2 19.0 22.2 26.5 35.4 19.1 7.0 12.4 34.5 19.7 17.7 24.2 17.7 23.6 25.3 18.2 13.7 29.0 25.2 17.1 50.5 MAP3K19 "FLJ23074, RCK, YSK4" ENSG00000176601 "Mitogen-activated protein kinase kinase kinase 19" Q56UN5 2 134964485-135047468 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.0;choroid plexus: 9.3;fallopian tube: 18.3;testis: 5.4" "Group enriched" "Detected in some" 8 "Early spermatids: 59.7;Endometrial ciliated cells: 73.7;Late spermatids: 148.4;Respiratory ciliated cells: 121.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011388 Uncertain Cytosol NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA011388: AB_1848822" "unprognostic (7.12e-3)" "unprognostic (6.55e-3)" "unprognostic (6.96e-2)" "unprognostic (3.90e-3)" "unprognostic (3.63e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (9.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.33e-1)" "unprognostic (2.02e-2)" "unprognostic (1.32e-1)" "unprognostic (4.04e-6)" "unprognostic (1.50e-1)" "unprognostic (4.13e-2)" "unprognostic (1.54e-1)" "unprognostic (2.83e-4)" 0.0 0.1 1.1 0.0 1.2 0.0 0.0 0.8 0.8 0.5 9.3 0.0 0.0 0.6 0.0 0.0 18.3 0.0 0.1 1.1 1.9 0.0 0.0 1.5 0.1 5.0 3.6 0.0 0.0 0.0 0.3 0.0 3.0 0.1 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 3.8 0.0 0.0 5.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.2 0.8 0.8 1.1 1.9 5.0 3.6 3.0 3.8 1.9 3.1 0.1 0.0 1.1 2.3 0.1 0.0 0.1 2.6 0.0 0.3 0.0 0.0 0.4 0.0 11.4 0.0 10.4 0.0 0.0 0.0 0.0 0.0 59.7 73.7 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 2.0 0.0 0.0 148.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 121.0 0.2 0.0 0.0 0.8 7.5 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 RAB3GAP1 "KIAA0066, RAB3GAP, RAB3GAP130, WARBM1" ENSG00000115839 "RAB3 GTPase activating protein catalytic subunit 1" Q15042 2 135052292-135176394 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034494, HPA034495" Approved Approved Nucleoplasm,Cytosol NA NA 6300 "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "HPA034494: AB_2674188, HPA034495: AB_10670158" "unprognostic (1.02e-2)" "unprognostic (2.43e-2)" "unprognostic (5.73e-2)" "prognostic unfavorable (2.96e-4)" "unprognostic (2.18e-1)" "unprognostic (9.57e-2)" "unprognostic (2.96e-2)" "unprognostic (7.00e-2)" "unprognostic (3.18e-1)" "unprognostic (1.13e-2)" "unprognostic (3.15e-2)" "unprognostic (2.05e-1)" "unprognostic (8.40e-3)" "unprognostic (2.41e-2)" "unprognostic (3.75e-1)" "unprognostic (4.11e-1)" "unprognostic (2.15e-1)" 23.4 21.1 22.5 24.3 24.1 37.5 25.6 18.7 23.1 27.5 22.0 23.7 19.1 29.2 30.6 26.2 22.9 21.6 35.2 24.5 24.1 23.2 20.5 20.4 25.9 23.3 23.2 35.2 35.4 34.0 18.9 23.6 24.3 29.5 27.9 34.1 35.6 28.3 36.9 26.2 21.4 30.9 19.7 21.3 26.1 18.7 23.1 30.3 30.8 36.0 30.4 26.0 22.4 22.0 51.2 20.4 34.8 29.0 67.3 57.0 32.4 76.6 62.6 59.5 58.4 45.3 40.7 75.5 46.2 78.5 22.8 42.2 37.4 70.6 72.1 36.2 37.9 34.3 24.8 39.9 46.9 46.8 39.3 50.2 91.2 54.8 98.2 53.6 43.6 33.7 49.5 42.5 54.7 30.1 24.1 18.2 27.1 30.7 33.8 40.9 45.0 31.9 35.0 44.9 28.3 22.4 52.0 30.7 36.8 30.5 27.2 33.6 53.0 60.0 45.7 26.0 32.5 30.1 18.2 55.8 39.2 27.8 34.3 10.3 4.3 6.7 1.5 5.3 1.3 5.5 3.8 2.1 4.5 6.8 7.9 4.2 1.7 3.1 6.0 2.3 5.4 2.1 22.5 24.1 18.7 23.1 24.5 24.1 23.3 23.2 24.3 19.7 23.1 22.0 34.3 25.6 26.7 86.8 50.4 30.2 46.8 28.8 27.9 28.9 30.2 27.8 58.0 32.9 32.6 31.3 50.1 23.6 15.3 39.4 11.7 20.0 34.8 31.8 33.0 28.5 34.6 24.4 137.8 26.9 17.1 35.5 46.9 31.5 46.3 27.2 32.9 25.7 22.4 30.3 106.8 31.2 28.5 26.7 28.1 23.2 30.7 32.4 23.2 112.4 24.2 18.0 6.2 107.1 123.3 34.6 24.3 35.7 40.0 42.5 29.9 21.1 36.0 33.8 46.0 31.8 34.4 41.8 25.8 37.5 29.7 39.1 28.3 35.0 24.7 51.0 ZRANB3 "AH2, DKFZP434B1727" ENSG00000121988 "Zinc finger RANBP2-type containing 3" Q5FWF4 2 135136916-135531218 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Astrocytes: 34.9;Excitatory neurons: 69.4;Inhibitory neurons: 46.2;Oligodendrocytes: 67.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035234 Supported Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA035234: AB_2674530" "unprognostic (6.98e-2)" "unprognostic (2.04e-1)" "unprognostic (1.01e-1)" "unprognostic (2.52e-3)" "unprognostic (4.09e-1)" "unprognostic (1.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.06e-1)" "unprognostic (3.53e-3)" "unprognostic (1.74e-1)" "unprognostic (3.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.77e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (2.00e-2)" "unprognostic (9.88e-2)" 0.8 1.4 0.5 0.9 0.7 1.1 0.8 0.2 0.8 1.0 0.2 0.7 0.5 0.9 0.5 0.7 0.9 0.7 0.9 0.6 0.3 0.7 1.1 0.6 0.6 0.1 0.1 1.5 1.3 0.6 1.4 0.5 0.2 0.9 0.4 1.5 0.7 0.5 2.0 0.8 0.6 0.4 0.1 0.8 0.7 3.2 0.3 0.8 1.0 0.6 0.4 0.8 0.8 0.7 0.9 0.9 1.7 1.1 0.8 1.5 1.5 1.3 0.9 0.9 1.1 1.5 0.7 2.8 1.3 1.0 0.6 0.9 2.4 1.1 1.6 2.5 1.8 3.2 0.4 3.5 0.6 2.5 0.6 1.3 1.0 1.3 3.2 1.5 1.3 1.6 3.1 1.3 0.7 1.3 1.5 1.4 1.1 0.8 1.1 1.8 1.3 1.0 1.3 0.6 1.8 2.3 1.1 0.5 0.9 1.6 0.9 1.1 1.0 0.7 0.6 0.4 0.8 1.1 1.4 2.6 1.0 1.7 1.0 0.1 0.1 0.1 0.1 0.0 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.5 0.7 0.2 0.8 0.6 0.3 0.1 0.1 0.2 0.1 0.3 0.7 1.7 3.2 1.5 34.9 7.3 1.3 4.5 4.5 8.0 5.8 2.8 2.3 3.3 2.8 4.3 0.0 8.4 5.7 2.0 0.5 0.0 2.0 16.9 3.2 5.0 1.9 1.8 10.1 69.4 0.9 8.3 4.7 1.5 3.5 0.0 9.1 1.8 8.9 2.5 5.0 46.2 1.2 4.1 0.8 1.5 4.5 3.1 2.3 0.0 26.2 2.9 2.7 2.1 24.6 67.0 1.4 1.7 2.2 4.7 2.1 0.4 4.5 1.6 7.5 0.0 8.3 3.4 14.1 10.3 4.8 2.3 3.8 3.9 10.8 2.6 3.0 R3HDM1 "KIAA0029, R3HDM" ENSG00000048991 "R3H domain containing 1" Q15032 2 135531455-135725270 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1088.8;Inhibitory neurons: 296.7;Oligodendrocyte precursor cells: 198.0;Oligodendrocytes: 173.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 5 "cerebral cortex: 53.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030936 Approved Nucleoplasm,Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "HPA030936: AB_10670835" "unprognostic (1.93e-1)" "unprognostic (4.32e-2)" "unprognostic (8.16e-3)" "unprognostic (1.10e-3)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "unprognostic (2.00e-3)" "prognostic unfavorable (8.02e-4)" "unprognostic (3.51e-2)" "unprognostic (9.52e-2)" "unprognostic (5.51e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (5.83e-7)" "unprognostic (1.16e-2)" "unprognostic (7.23e-2)" "unprognostic (4.32e-3)" "unprognostic (2.47e-1)" 10.3 10.5 0.0 13.6 7.7 23.2 8.2 0.0 53.0 9.5 0.0 11.8 7.2 10.1 9.6 9.5 8.2 9.6 7.9 10.5 0.0 9.0 9.7 7.9 18.1 0.0 0.0 7.7 13.0 22.8 20.1 6.7 0.0 8.0 15.1 17.7 7.0 8.8 22.7 8.4 9.1 13.1 0.0 10.8 8.6 22.8 0.0 43.6 13.2 15.6 20.9 12.0 7.2 0.0 50.7 30.5 42.1 49.0 22.2 30.0 24.8 31.1 32.2 30.5 33.2 54.7 34.2 79.8 24.0 44.3 22.2 22.3 55.6 57.5 53.3 50.4 27.9 64.3 37.0 55.1 26.5 55.4 39.9 28.5 25.2 53.7 68.5 27.7 49.8 85.2 67.9 66.4 35.4 52.0 96.5 38.0 32.6 37.6 35.4 56.8 29.1 47.6 30.3 43.9 42.9 33.3 49.9 20.2 22.0 36.5 27.1 29.4 37.0 28.1 27.8 35.7 39.3 52.7 78.8 74.1 31.6 44.7 36.7 3.5 6.9 2.8 5.1 7.3 4.9 5.5 5.3 7.6 9.9 3.6 5.1 5.9 1.0 9.1 6.7 11.2 8.5 4.4 0.0 7.7 0.0 53.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 6.4 3.1 125.7 20.1 7.9 7.2 9.9 10.8 39.3 11.0 9.7 16.0 14.3 14.1 7.3 20.9 8.1 31.2 5.4 19.6 8.8 46.7 6.8 27.0 15.6 22.9 30.7 1088.8 7.4 10.4 11.5 15.8 12.6 18.3 25.9 11.7 14.2 12.2 26.9 296.7 11.7 14.2 19.5 13.8 44.7 13.7 18.8 7.2 98.4 21.9 8.6 22.6 198.0 173.5 8.3 6.3 11.3 33.7 10.0 5.3 13.4 4.3 40.5 0.0 14.7 25.3 26.5 24.5 20.3 9.7 3.1 23.4 36.6 11.5 6.8 UBXN4 "KIAA0242, UBXD2, UBXDC1" ENSG00000144224 "UBX domain protein 4" Q92575 2 135741734-135785056 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 863.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036325 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA036325: AB_10669788" "unprognostic (1.22e-2)" "unprognostic (1.08e-1)" "unprognostic (5.24e-2)" "unprognostic (1.47e-1)" "unprognostic (1.54e-1)" "unprognostic (1.90e-1)" "unprognostic (1.17e-1)" "unprognostic (2.91e-1)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (2.63e-2)" "unprognostic (1.93e-1)" "unprognostic (1.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (5.14e-3)" 51.9 55.6 33.3 58.4 38.3 65.4 57.4 37.4 38.0 62.3 44.7 57.1 69.8 56.0 71.1 44.4 49.0 57.2 44.3 31.5 33.8 64.2 93.8 47.2 59.5 40.2 36.8 52.6 73.4 83.5 19.6 63.0 40.1 64.6 60.2 85.6 71.8 47.8 55.1 56.0 67.9 43.9 35.9 55.7 64.6 57.7 33.7 76.6 76.1 52.7 59.8 60.5 25.1 47.6 136.2 34.6 85.1 66.2 106.9 107.0 95.5 106.6 106.3 87.0 77.4 65.3 91.8 84.0 149.4 105.1 46.6 98.3 50.7 68.4 103.5 115.5 62.8 80.5 60.7 98.6 99.4 85.2 70.7 81.6 66.6 86.7 85.8 118.2 110.5 66.2 74.4 116.1 95.3 64.1 109.9 61.3 64.3 70.6 70.9 87.9 100.5 146.5 112.2 97.7 77.4 50.2 97.2 64.1 64.4 77.1 68.0 78.2 101.8 78.4 40.1 82.5 58.4 108.7 72.2 76.2 99.0 59.3 75.5 62.9 35.8 59.1 46.5 42.3 42.6 45.9 42.5 42.5 35.8 42.6 41.4 41.0 73.7 48.4 52.2 56.6 52.3 35.9 33.3 38.3 37.4 38.0 31.5 33.8 40.2 36.8 40.1 35.9 33.7 47.6 178.1 208.3 171.4 56.2 177.4 175.1 283.0 318.5 160.5 172.3 164.1 153.3 150.8 134.4 264.1 126.9 223.1 238.2 140.8 168.9 90.1 254.6 863.9 209.3 223.1 151.7 186.6 129.8 85.2 195.8 214.0 197.4 129.5 240.6 176.9 151.5 113.2 225.7 138.8 97.6 78.4 246.9 183.1 88.6 125.2 325.1 172.7 139.9 92.5 60.9 158.8 162.2 122.6 71.9 105.3 190.7 166.7 143.7 300.3 344.1 183.0 156.8 286.7 349.8 105.2 159.3 173.9 446.1 248.4 176.1 183.6 379.4 171.6 271.6 186.0 303.7 LCT ENSG00000115850 Lactase P09848 2 135787850-135837184 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosidase, Hydrolase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 187 "intestine: 225.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.4;Breast myoepithelial cells: 3.3;Early spermatids: 1.3;Proximal enterocytes: 2.8;Undifferentiated cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "JURKAT: 2.5;MOLT-4: 4.9;RPMI-8226: 9.7" "Region enriched" "Detected in some" 15 "hippocampal formation: 15.7" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.21e-2)" "unprognostic (1.65e-4)" "unprognostic (2.54e-1)" "unprognostic (2.06e-1)" "unprognostic (3.39e-2)" "unprognostic (8.03e-4)" "unprognostic (3.55e-3)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (3.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.32e-2)" "unprognostic (1.64e-4)" "unprognostic (4.90e-2)" "unprognostic (8.92e-2)" "unprognostic (8.97e-2)" "unprognostic (1.02e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 225.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136.3 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.0 4.9 0.8 0.0 0.0 0.0 1.1 0.0 9.7 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.3 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 48.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Erythroid cells: 50.5;Spermatogonia: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004818, CAB009577" Enhanced Enhanced Nucleoplasm NA Yes 33000 "Cluster 44: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "CAB009577: AB_2266309, HPA004818: AB_1079339" "unprognostic (6.73e-2)" "unprognostic (6.68e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-3)" "unprognostic (8.98e-2)" "unprognostic (4.34e-2)" "prognostic unfavorable (5.70e-7)" "unprognostic (1.71e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (2.36e-2)" "unprognostic (1.36e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (8.29e-12)" "unprognostic (2.84e-1)" "unprognostic (9.02e-2)" "unprognostic (7.42e-2)" "unprognostic (1.68e-1)" 10.0 5.3 4.7 20.7 5.1 35.6 11.6 6.3 6.4 10.2 3.5 12.8 11.7 10.0 5.1 11.1 7.9 6.8 5.3 5.0 5.1 6.4 9.5 7.8 34.4 4.4 4.6 11.3 3.9 4.6 3.0 12.6 4.7 6.9 15.6 3.2 6.0 8.3 8.1 10.5 13.2 11.8 4.8 9.9 8.2 14.6 5.4 48.5 4.5 7.6 38.0 9.6 8.9 5.5 104.4 62.8 133.8 85.7 28.2 36.5 52.3 73.9 55.8 84.3 93.0 129.3 77.7 181.0 52.9 54.0 36.9 60.4 136.7 67.6 89.5 93.6 94.4 179.9 85.0 40.9 13.1 218.4 76.9 21.7 8.6 61.7 18.9 16.8 58.1 139.8 130.8 147.9 62.6 106.3 268.6 159.6 120.9 91.3 62.1 131.1 159.9 165.7 42.3 90.3 83.7 71.3 97.6 45.9 47.0 95.2 53.1 135.4 29.0 58.3 48.0 63.4 56.8 87.8 153.7 234.2 81.4 163.5 70.9 9.2 1.6 1.1 8.1 4.7 7.6 6.1 11.1 9.9 5.2 4.7 9.9 12.4 0.9 9.1 4.5 10.6 16.1 6.3 4.7 5.1 6.3 6.4 5.0 5.1 4.4 4.6 4.7 4.8 5.4 5.5 6.4 0.0 2.7 3.9 10.3 6.6 4.1 5.4 7.4 3.3 4.2 5.8 4.6 2.8 5.4 3.7 0.0 40.1 28.2 3.0 0.0 7.2 3.2 2.5 8.9 8.3 2.4 50.5 3.5 6.6 28.0 13.3 9.7 7.1 9.5 27.2 8.9 3.0 24.4 3.3 3.4 11.7 0.0 4.7 3.5 2.1 9.3 9.6 5.4 3.7 3.2 2.4 4.1 2.0 2.8 3.9 4.9 17.0 27.6 1.6 2.4 0.9 3.0 0.5 0.0 7.2 10.0 26.6 40.4 10.2 4.1 10.7 22.0 9.6 15.4 2.7 DARS1 DARS ENSG00000115866 "Aspartyl-tRNA synthetase 1" P14868 2 135905881-135986100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 85.1;Cytotrophoblasts: 115.4;Extravillous trophoblasts: 157.9;Hofbauer cells: 94.2;Syncytiotrophoblasts: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020451, HPA029804, HPA029805" Enhanced Enhanced Cytosol NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "HPA020451: AB_1847479, HPA029804: AB_10599178, HPA029805: AB_10601994" "unprognostic (6.13e-2)" "unprognostic (8.16e-3)" "unprognostic (5.54e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (2.39e-6)" "unprognostic (2.98e-3)" "prognostic unfavorable (7.57e-4)" "unprognostic (6.00e-3)" "prognostic unfavorable (6.54e-4)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.24e-5)" "unprognostic (1.04e-1)" "unprognostic (9.12e-2)" "unprognostic (3.94e-3)" "unprognostic (2.00e-1)" 37.5 42.1 30.1 41.2 31.2 34.0 48.7 33.3 52.1 34.7 28.0 38.5 23.5 38.4 22.8 46.0 37.8 25.8 42.3 29.5 35.2 47.3 44.2 27.8 48.3 32.6 31.2 47.2 36.1 38.4 24.6 44.4 35.6 33.6 26.6 87.1 32.5 36.5 82.8 40.2 28.0 39.3 34.0 32.3 33.3 17.8 30.7 63.1 43.4 60.1 55.4 40.0 36.4 35.3 201.6 77.0 73.4 66.3 61.0 78.1 141.6 99.8 92.6 92.2 91.1 163.0 84.0 210.0 159.8 78.4 86.6 111.7 94.9 114.9 170.3 95.6 86.0 134.0 76.8 185.6 83.9 188.3 90.8 84.5 75.6 109.1 99.8 122.9 46.8 106.3 131.6 66.0 66.6 87.3 139.2 117.4 77.8 85.3 66.9 179.3 157.9 139.0 91.8 76.9 40.3 89.6 75.0 63.5 74.8 72.2 66.8 118.2 38.2 86.0 87.4 64.5 92.8 194.9 123.3 250.2 144.1 132.3 51.0 33.7 85.4 51.2 115.2 82.6 174.7 219.9 172.6 151.4 133.7 198.8 175.2 154.2 31.7 171.9 67.4 130.4 168.9 153.3 30.1 31.2 33.3 52.1 29.5 35.2 32.6 31.2 35.6 34.0 30.7 35.3 29.4 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.1 0.0 0.0 0.0 0.0 115.4 20.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 157.9 18.2 0.0 0.0 0.0 0.0 0.0 0.0 94.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 136.4 4.4 0.0 0.0 0.0 CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136118149 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1175.1;lymphoid tissue: 549.3" "Cell type enhanced" "Detected in many" "B-cells: 1446.9;dendritic cells: 1015.1;Langerhans cells: 486.2;Macrophages: 513.6;Plasma cells: 534.2;T-cells: 1436.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 580.8;JURKAT: 323.6;Karpas-707: 302.1;MOLT-4: 538.9;REH: 281.0;U-266/70: 648.5;U-698: 677.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" 51.8 184.5 11.8 297.9 11.4 1175.1 39.6 14.6 23.8 36.1 20.1 33.2 12.6 35.2 5.5 34.9 64.9 84.5 21.8 10.6 19.7 29.0 52.4 95.5 383.8 24.3 12.8 12.9 10.0 12.3 32.6 57.5 18.2 34.1 48.6 7.8 30.2 11.8 5.2 9.8 246.5 28.1 16.7 346.5 64.0 4.0 15.2 491.2 36.7 12.0 549.3 99.3 26.9 32.3 0.8 0.3 9.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 580.8 1.8 0.0 0.4 0.7 1.7 0.0 0.0 29.6 6.9 35.1 84.3 0.0 0.0 81.5 60.7 0.0 0.0 0.0 0.0 0.0 54.5 323.6 1.0 302.1 0.0 1.5 538.9 72.8 9.3 45.4 2.9 281.0 62.6 102.5 4.5 0.0 30.9 26.1 0.6 2.0 0.3 2.9 0.7 156.7 8.1 0.0 2.0 0.5 0.4 648.5 116.7 677.4 0.1 131.8 0.1 87.0 28.5 117.8 83.8 15.6 67.3 115.6 76.5 79.6 25.7 166.2 113.1 109.5 143.3 17.2 9.1 63.7 76.1 51.9 11.8 11.4 14.6 23.8 10.6 19.7 24.3 12.8 18.2 16.7 15.2 32.3 32.0 16.0 42.2 8.5 1446.9 41.0 5.7 0.3 9.6 8.6 46.1 42.2 5.2 11.5 4.4 3.7 0.0 1.5 1015.1 1.1 13.7 5.1 1.2 20.0 8.9 67.6 1.8 67.5 0.0 0.9 4.2 28.9 52.0 71.0 12.6 9.0 29.6 9.1 159.9 0.0 0.2 2.0 10.2 270.0 486.2 2.9 1.5 513.6 113.8 3.7 189.2 1.0 153.5 0.0 2.0 2.3 1.1 2.6 534.2 3.2 0.0 3.2 2.4 0.8 46.0 99.1 23.1 0.5 7.8 8.5 35.7 6.3 1436.5 4.6 1.8 4.5 THSD7B KIAA1679 ENSG00000144229 "Thrombospondin type 1 domain containing 7B" Q9C0I4 2 136765545-137677718 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;retina: 19.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 25.0;Horizontal cells: 90.9;Inhibitory neurons: 153.4;Rod photoreceptor cells: 32.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Daudi: 11.0;SCLC-21H: 22.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA051416, HPA056745" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA051416: AB_2681477, HPA056745: AB_2683224" "unprognostic (4.65e-3)" "unprognostic (2.25e-1)" "unprognostic (8.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.59e-3)" "unprognostic (1.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.80e-3)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (3.20e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-6)" "unprognostic (2.42e-3)" "unprognostic (1.89e-1)" "unprognostic (4.31e-2)" "unprognostic (4.30e-2)" 1.9 0.0 0.8 0.0 1.2 0.0 0.7 0.6 1.2 0.2 0.1 0.1 0.0 0.2 4.1 0.3 0.9 0.2 0.5 1.2 2.3 0.9 0.1 0.1 0.0 8.2 3.3 0.0 0.0 0.3 0.6 0.2 8.9 0.7 0.0 19.7 0.4 0.2 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 1.6 0.8 0.7 0.1 0.0 0.2 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 11.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.4 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.6 1.2 1.2 2.3 8.2 3.3 8.9 0.6 1.6 1.6 1.1 0.0 0.0 2.6 0.0 0.1 0.7 0.0 13.6 1.6 0.1 0.9 0.8 0.0 0.0 0.0 25.0 0.0 0.0 0.0 1.9 0.0 3.7 0.5 0.2 0.8 0.0 0.0 9.5 0.0 0.0 0.2 0.0 1.4 0.0 1.7 1.8 0.0 0.0 90.9 153.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 8.4 0.0 1.8 0.0 1.5 7.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 32.2 6.6 0.3 3.3 0.5 0.5 1.4 0.0 0.0 0.0 0.4 0.0 0.1 HNMT ENSG00000150540 "Histamine N-methyltransferase" P50135 2 137964020-138016364 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 299.3;Kupffer cells: 263.7;Proximal tubular cells: 268.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 21 "classical monocyte: 110.9;intermediate monocyte: 89.8;myeloid DC: 68.3;non-classical monocyte: 52.2" "Group enriched" "Detected in many" 23 "dendritic cells: 68.3;monocytes: 110.9" "Cell line enhanced" "Detected in many" "Hep G2: 227.2;HSkMC: 87.9;RT4: 117.1;SuSa: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035480, HPA035481, HPA073754" Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA 130000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Cytosol" Centrosome "HPA035480: AB_2674645, HPA035481: AB_10672094, HPA073754: " "unprognostic (1.32e-1)" "unprognostic (3.53e-1)" "unprognostic (5.44e-2)" "unprognostic (2.09e-2)" "unprognostic (2.81e-1)" "unprognostic (2.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (5.24e-2)" "unprognostic (1.34e-2)" "unprognostic (1.76e-2)" "unprognostic (5.34e-2)" "unprognostic (1.21e-1)" "prognostic favorable (4.68e-4)" 70.4 18.2 13.0 41.7 13.3 12.6 62.3 13.1 18.8 57.3 19.2 53.9 29.3 62.8 27.1 17.5 34.5 68.7 21.7 15.6 19.1 109.7 245.9 49.0 35.1 16.0 15.3 91.0 29.0 40.2 9.5 46.8 18.1 37.0 56.4 6.1 30.5 44.3 5.9 17.4 29.1 33.1 16.1 37.5 29.1 10.3 14.5 8.2 14.6 11.9 16.4 49.7 24.5 22.2 0.7 0.9 5.6 14.6 61.9 64.6 0.4 3.9 6.2 0.4 2.3 29.7 15.7 0.9 50.2 17.0 0.8 1.1 11.9 0.0 0.1 0.7 4.9 0.2 44.5 227.2 28.0 0.3 0.6 87.9 0.1 21.5 0.0 4.7 15.9 0.1 0.5 0.7 47.4 3.7 0.0 0.5 28.1 39.3 5.6 0.5 1.5 0.2 67.9 117.1 0.1 0.8 22.1 28.4 0.1 107.9 1.0 53.2 4.8 4.8 11.8 6.2 16.3 0.4 0.3 0.7 20.9 27.8 3.3 1.3 110.9 0.7 0.5 89.8 0.3 1.8 0.2 0.2 68.3 0.5 0.3 0.4 3.9 0.5 52.2 1.5 0.7 32.6 13.0 13.3 13.1 18.8 15.6 19.1 16.0 15.3 18.1 16.1 14.5 22.2 15.5 28.9 44.1 9.4 5.0 35.6 81.5 64.6 30.7 0.7 78.1 65.4 2.2 133.0 88.9 60.7 0.0 54.9 2.6 59.4 123.3 122.1 1.5 28.3 50.6 9.4 16.4 16.8 16.8 48.0 81.6 54.2 20.9 115.3 0.0 17.4 19.2 165.7 299.3 0.0 13.8 67.8 24.4 263.7 97.2 4.2 131.4 127.4 56.9 31.9 122.0 25.5 4.1 45.8 14.3 71.0 108.6 105.3 0.2 39.8 31.9 268.3 38.4 0.8 78.9 55.2 55.7 0.5 0.9 33.2 25.9 37.6 4.0 43.9 83.5 126.1 SPOPL BTBD33 ENSG00000144228 "Speckle type BTB/POZ protein like" Q6IQ16 2 138501770-138573547 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034687 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034687: AB_10670573" "unprognostic (1.39e-3)" "unprognostic (1.24e-1)" "unprognostic (2.48e-2)" "unprognostic (3.02e-2)" "unprognostic (3.37e-1)" "unprognostic (3.12e-2)" "unprognostic (4.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (2.75e-2)" "unprognostic (8.90e-2)" "prognostic favorable (3.63e-4)" "unprognostic (2.25e-2)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (1.91e-3)" 7.9 5.9 6.1 9.7 8.1 14.2 12.7 6.7 8.0 6.6 4.8 8.3 7.9 8.5 3.6 6.2 6.6 7.3 5.4 5.5 6.2 8.8 9.4 7.6 11.3 7.6 9.1 10.3 5.6 7.3 4.3 6.8 7.9 9.4 8.9 9.8 11.5 8.1 4.6 8.5 8.4 7.4 7.6 11.2 9.3 3.7 7.1 4.9 8.5 8.0 9.7 8.0 6.3 9.1 13.3 4.0 7.2 7.0 5.8 9.7 13.8 9.6 7.2 5.9 7.0 14.8 10.6 14.2 9.0 8.3 5.3 5.1 9.5 8.4 12.4 11.1 7.7 9.0 9.2 23.2 6.0 10.0 12.1 6.4 12.3 11.7 10.8 12.0 9.6 3.3 3.0 19.2 10.1 12.9 1.0 9.4 6.5 9.3 6.9 5.0 12.6 8.1 9.3 18.7 8.4 10.3 14.7 13.8 7.3 8.5 7.6 10.9 9.6 9.5 8.1 12.0 14.7 27.6 21.6 10.3 15.9 9.2 8.8 0.4 1.6 2.8 0.3 1.5 0.3 1.1 0.2 0.3 2.2 1.1 0.1 0.2 5.7 0.4 1.3 0.9 0.4 0.6 6.1 8.1 6.7 8.0 5.5 6.2 7.6 9.1 7.9 7.6 7.1 9.1 16.9 12.8 13.6 25.8 25.9 55.6 11.4 7.9 13.6 9.9 38.8 13.8 13.2 15.7 20.6 3.7 4.2 6.4 15.0 20.3 7.9 10.1 1.7 11.9 10.3 12.4 19.2 5.0 55.3 13.3 7.3 12.3 17.3 11.8 8.8 12.5 8.9 13.8 8.9 18.5 67.2 19.8 18.3 31.5 37.7 2.8 17.1 33.2 12.4 48.7 27.5 9.2 9.2 63.8 54.1 21.1 12.6 15.8 11.8 19.5 11.0 16.4 16.1 16.6 6.6 18.8 18.5 10.0 18.8 10.3 44.8 6.2 10.8 4.9 12.0 21.3 NXPH2 NPH2 ENSG00000144227 "Neurexophilin 2" O95156 2 138669157-138780390 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;kidney: 4.1;ovary: 8.1" "Cell type enriched" "Detected in some" 6 "Inhibitory neurons: 156.1" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Group enriched" "Detected in many" 6 "medulla oblongata: 11.7;midbrain: 7.6;pons: 13.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.4;SiHa: 3.0;SuSa: 2.1;U-2 OS: 4.7;U-251 MG: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA034759 Approved "Secreted in brain" NA Yes "Cluster 73: Brain - Neuropeptide signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034759: AB_10669732" "unprognostic (5.83e-2)" "unprognostic (8.83e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.80e-1)" 0.2 0.0 1.8 0.1 1.7 0.0 0.1 1.0 1.8 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.0 0.4 4.1 0.0 0.0 0.0 11.7 7.6 8.1 0.0 0.0 0.1 0.1 13.1 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.6 3.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 4.7 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.7 1.0 1.8 1.0 0.4 11.7 7.6 13.1 1.9 1.1 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 156.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.4;urinary bladder: 51.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 136.1;Club cells: 109.6;Ionocytes: 114.0;Langerhans cells: 190.5;Macrophages: 122.9;monocytes: 248.0;Syncytiotrophoblasts: 104.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 17 "classical monocyte: 109.4;intermediate monocyte: 142.7;memory B-cell: 73.6;myeloid DC: 111.2;naive B-cell: 51.3;non-classical monocyte: 123.4;plasmacytoid DC: 77.7" "Group enriched" "Detected in many" 19 "B-cells: 73.6;dendritic cells: 111.2;monocytes: 142.7" "Cell line enhanced" "Detected in many" "A549: 185.2;GAMG: 298.5;HeLa: 195.5;Hep G2: 128.3;hTEC/SVTERT24-B: 106.5;U-87 MG: 314.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 590000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol Nucleoplasm "HPA031686: AB_2673995" "unprognostic (2.58e-2)" "unprognostic (3.39e-3)" "unprognostic (1.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.65e-2)" "unprognostic (9.04e-2)" "unprognostic (5.36e-3)" "unprognostic (3.58e-3)" "unprognostic (4.88e-2)" "unprognostic (3.35e-2)" "unprognostic (2.87e-3)" "unprognostic (1.51e-1)" "unprognostic (1.40e-3)" "unprognostic (3.33e-3)" "unprognostic (3.65e-2)" "unprognostic (5.24e-2)" "unprognostic (1.64e-1)" 5.2 4.0 2.4 24.4 2.1 10.8 30.8 2.7 4.5 4.0 3.6 2.4 1.1 2.5 1.3 6.7 1.2 9.8 1.2 2.0 1.6 18.6 88.4 13.5 15.0 2.8 1.7 0.4 0.9 0.8 1.2 7.3 3.3 0.9 2.9 1.5 1.8 0.7 0.7 1.3 3.0 4.8 0.5 8.9 5.8 16.6 6.6 3.9 2.3 0.3 28.9 51.5 3.4 2.1 0.2 185.2 0.3 0.4 0.4 0.6 0.5 0.4 5.1 0.2 0.2 3.3 2.7 11.9 0.5 0.1 298.5 0.7 0.1 0.2 0.2 0.6 0.2 4.3 195.5 128.3 2.4 0.4 0.8 17.3 15.0 106.5 0.6 0.2 0.2 0.3 0.5 1.1 1.7 96.7 0.2 11.8 0.7 0.2 0.9 0.2 0.9 0.4 3.2 96.0 0.5 0.3 102.2 15.2 1.0 1.0 50.9 26.5 1.5 5.9 0.5 89.1 0.3 0.7 0.3 0.3 314.5 22.2 0.6 0.7 109.4 2.4 0.5 142.7 0.4 73.6 0.6 0.3 111.2 51.3 0.5 0.3 5.8 1.8 123.4 77.7 0.6 49.2 2.4 2.1 2.7 4.5 2.0 1.6 2.8 1.7 3.3 0.5 6.6 2.1 3.0 3.2 2.7 0.7 46.8 4.0 0.5 136.1 0.0 0.5 5.8 0.9 1.6 7.2 109.6 3.7 4.2 3.3 16.1 0.7 5.9 14.5 46.3 1.5 1.1 5.1 0.0 2.5 1.3 9.5 2.3 1.8 20.4 15.7 0.0 0.0 2.5 49.1 38.8 10.1 0.9 0.0 114.0 64.7 190.5 42.8 1.8 122.9 1.8 29.0 248.0 0.2 1.0 0.5 0.8 59.6 1.1 0.4 5.1 1.1 0.0 44.4 21.1 0.6 6.6 0.5 3.9 47.8 8.0 1.5 3.1 104.7 2.2 0.1 1.0 22.6 ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.8;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in many" "B-cells: 126.3;Early spermatids: 132.3;granulocytes: 88.5;Microglial cells: 250.1;NK-cells: 89.6;T-cells: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 59.4;HEL: 75.8;HL-60: 124.3;MOLT-4: 82.0;NB-4: 100.4;THP-1: 131.0;U-698: 89.5;U-937: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032125 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA 38000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus, Vesicles" Nucleoplasm "HPA032125: AB_10671370" "unprognostic (1.59e-2)" "unprognostic (2.40e-3)" "unprognostic (8.63e-2)" "unprognostic (2.19e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-3)" "unprognostic (6.14e-2)" "unprognostic (2.18e-3)" "unprognostic (1.32e-2)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (4.40e-2)" "unprognostic (2.12e-2)" "unprognostic (4.58e-2)" "unprognostic (6.94e-2)" 6.9 5.9 1.4 27.1 1.3 79.8 7.6 2.3 2.3 4.1 1.9 7.3 6.8 2.6 9.7 4.0 2.8 11.4 5.6 1.2 2.2 4.4 10.2 9.8 59.3 3.0 1.9 1.8 1.3 1.7 1.0 4.0 2.7 4.3 7.7 1.3 4.2 5.1 1.2 2.0 15.1 3.9 1.9 44.9 7.5 7.4 2.1 75.2 4.5 2.2 46.3 11.4 4.3 4.0 0.3 0.1 4.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 59.4 0.2 0.1 0.1 0.1 0.2 0.1 0.3 14.6 0.0 75.8 0.5 0.1 0.0 124.3 1.2 0.0 0.0 0.2 0.2 0.1 0.0 47.0 0.3 4.4 0.0 0.1 82.0 100.4 0.3 0.0 0.1 44.7 0.6 22.7 0.0 0.1 0.2 0.4 0.3 0.2 1.0 0.1 4.5 131.0 0.6 0.4 1.2 0.1 0.2 1.0 0.3 89.5 0.7 63.9 3.9 181.8 32.0 140.1 97.7 34.3 161.6 94.3 172.8 125.7 56.3 86.2 119.0 101.7 207.2 121.4 40.5 54.3 147.7 99.9 1.4 1.3 2.3 2.3 1.2 2.2 3.0 1.9 2.7 1.9 2.1 4.0 8.2 0.0 9.6 2.0 126.3 5.6 0.1 0.0 0.0 0.3 1.8 2.0 3.9 1.5 2.5 0.0 0.0 0.2 78.9 0.3 0.0 0.1 132.3 1.8 2.3 4.3 0.0 26.3 12.2 0.0 0.3 9.7 8.6 3.5 88.5 0.0 8.6 0.8 21.3 1.7 6.8 0.0 0.0 39.9 30.9 17.5 14.9 43.0 8.8 250.1 34.9 0.4 89.6 20.6 3.2 0.0 0.0 3.4 65.8 0.2 0.0 0.7 2.2 0.3 46.0 2.7 31.6 68.4 1.2 0.4 4.5 0.3 149.2 0.1 0.2 0.2 GTDC1 "FLJ11753, Hmat-Xa" ENSG00000121964 "Glycosyltransferase like domain containing 1" Q4AE62 2 143938068-144332568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 330.7;Inhibitory neurons: 188.0;Microglial cells: 130.2;Oligodendrocyte precursor cells: 196.6;Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036694 Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA036694: AB_10671709" "unprognostic (1.44e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (3.36e-2)" "unprognostic (5.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.81e-7)" "unprognostic (8.01e-2)" "unprognostic (4.13e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-3)" "unprognostic (6.96e-2)" "prognostic unfavorable (6.60e-4)" "unprognostic (2.44e-1)" "unprognostic (8.23e-2)" "unprognostic (6.31e-3)" "unprognostic (1.89e-1)" 15.2 12.6 15.9 7.5 18.0 14.2 9.4 11.7 21.1 11.8 4.2 7.1 4.2 6.7 9.4 7.4 5.8 10.1 15.7 17.3 14.3 9.6 6.7 7.8 11.0 15.4 14.7 12.0 7.2 7.4 4.2 9.5 15.4 6.1 6.7 7.7 6.1 5.8 10.0 5.1 4.8 5.9 17.2 13.5 5.2 12.2 14.3 8.7 10.5 11.3 11.6 9.5 5.5 24.1 6.9 2.8 20.0 3.7 20.1 18.4 6.0 4.7 11.9 10.3 14.2 3.1 6.3 14.8 3.3 8.5 6.6 1.9 4.0 7.1 21.9 19.2 4.7 23.0 2.6 3.3 8.3 9.4 12.0 12.8 17.1 11.1 16.2 7.0 14.9 6.1 4.2 16.8 23.7 3.2 2.5 10.3 5.7 5.3 4.5 7.0 10.4 4.0 11.4 14.0 10.2 7.9 9.1 7.7 9.3 12.4 5.1 10.5 9.2 11.4 8.3 5.1 6.0 10.6 0.0 8.5 6.6 6.2 15.6 2.3 2.6 7.9 5.5 2.4 11.8 4.3 3.6 9.3 2.1 3.5 0.8 5.9 11.3 8.5 2.7 0.7 5.1 3.6 15.9 18.0 11.7 21.1 17.3 14.3 15.4 14.7 15.4 17.2 14.3 24.1 7.7 9.6 23.2 82.3 11.2 7.1 4.4 6.4 4.0 20.4 5.2 5.0 18.5 4.3 14.9 5.5 4.2 4.1 13.6 6.1 5.9 4.5 9.9 3.3 11.4 9.6 4.2 9.4 330.7 10.5 5.2 16.0 4.6 5.6 17.7 15.5 20.3 3.8 10.2 18.5 188.0 3.2 4.1 18.3 11.8 7.7 12.8 16.4 5.4 130.2 11.6 10.8 18.6 196.6 399.6 9.4 4.0 13.9 8.6 4.2 2.6 7.7 13.4 3.9 13.1 25.2 17.0 5.4 23.5 4.9 4.7 4.2 19.7 14.8 3.7 8.7 ZEB2 "KIAA0569, SIP-1, SIP1, ZFHX1B" ENSG00000169554 "Zinc finger E-box binding homeobox 2" O60315 2 144364364-144521057 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant, Epilepsy, Hirschsprung disease, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 363.7" "Cell type enhanced" "Detected in many" "Horizontal cells: 662.9;Inhibitory neurons: 539.3;Oligodendrocytes: 1489.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 154.0;THP-1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003456 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoli "Nucleoplasm, Cytosol" "HPA003456: AB_10603840" "unprognostic (1.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (4.12e-1)" "unprognostic (4.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.77e-2)" "unprognostic (5.83e-2)" "unprognostic (7.90e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (6.04e-5)" "unprognostic (1.11e-2)" "unprognostic (1.73e-2)" "unprognostic (7.45e-2)" "unprognostic (1.32e-2)" 61.3 45.2 185.6 56.8 258.3 127.5 29.5 138.3 165.5 52.4 3.0 24.5 21.9 29.6 9.6 27.9 20.3 43.9 45.7 132.5 155.4 18.2 23.3 41.2 43.2 238.3 214.5 70.5 5.7 6.7 3.3 62.1 222.8 18.5 29.9 35.5 9.6 22.7 20.8 12.8 25.9 33.3 183.2 69.4 18.0 16.2 249.6 10.6 13.3 18.8 24.2 46.6 24.1 363.7 1.6 2.0 83.4 0.1 98.9 49.7 0.3 35.1 35.1 38.5 37.1 0.0 0.8 6.6 0.1 37.4 10.6 0.4 14.5 0.1 47.6 37.6 11.2 154.0 6.3 0.2 23.0 26.4 113.2 42.1 0.9 48.9 22.9 33.7 29.4 0.0 43.0 4.1 45.2 0.2 0.4 79.9 12.3 0.0 1.9 44.1 63.5 0.2 0.4 0.6 0.7 22.1 4.2 0.2 97.3 27.5 0.2 181.4 45.9 42.9 0.7 87.5 11.0 47.1 0.3 7.5 66.7 78.4 122.6 27.8 47.7 12.2 21.0 42.6 1.9 9.2 2.7 10.7 27.0 9.4 1.9 7.7 15.2 7.3 43.9 21.5 0.6 19.0 185.6 258.3 138.3 165.5 132.5 155.4 238.3 214.5 222.8 183.2 249.6 363.7 32.6 6.4 19.2 121.8 92.4 24.9 1.2 0.6 3.4 158.6 2.2 4.3 71.0 1.5 10.1 5.5 4.2 1.7 426.2 0.1 1.9 0.7 2.2 2.1 84.7 29.2 0.0 127.0 228.2 0.8 2.0 123.0 13.3 2.5 157.5 99.3 79.2 4.6 144.5 662.9 539.3 0.0 0.0 435.0 276.3 7.2 120.5 435.0 103.2 343.8 233.6 69.3 223.5 381.0 1489.6 0.2 1.1 66.5 132.3 1.8 0.0 10.3 4.0 11.9 184.1 185.0 198.7 2.9 11.3 3.4 19.6 4.7 136.7 108.8 0.4 2.2 ACVR2A "ACTRII, ACVR2" ENSG00000121989 "Activin A receptor type 2A" P27037 2 147844517-147930826 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 62.5;Inhibitory neurons: 63.4;Oligodendrocyte precursor cells: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 26.3;RH-30: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046997 Approved Approved Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA046997: AB_10970077" "unprognostic (4.55e-2)" "unprognostic (2.26e-2)" "unprognostic (2.09e-1)" "unprognostic (7.34e-3)" "unprognostic (2.75e-1)" "unprognostic (1.17e-1)" "unprognostic (4.41e-3)" "unprognostic (8.73e-3)" "unprognostic (1.30e-2)" "unprognostic (3.61e-1)" "unprognostic (1.34e-2)" "unprognostic (1.52e-1)" "prognostic favorable (1.62e-4)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (3.99e-2)" 7.3 4.0 6.2 4.6 7.4 3.3 7.0 10.8 6.4 5.4 1.0 6.3 7.7 5.2 6.6 7.2 4.5 7.7 3.7 7.5 7.5 5.6 7.4 4.6 3.1 2.6 4.5 4.5 4.4 4.3 3.9 7.7 3.9 6.8 6.5 8.3 7.5 5.2 17.5 19.5 9.3 7.0 3.8 4.0 6.8 6.4 8.6 2.3 6.7 6.3 3.9 7.4 7.4 4.6 1.8 2.1 13.2 5.0 7.3 4.7 5.4 4.1 5.0 6.9 12.0 5.8 8.1 0.1 3.6 6.7 2.5 6.2 12.0 6.1 8.8 1.4 7.3 0.9 3.6 10.2 26.3 1.0 0.9 8.1 7.3 4.5 8.9 5.2 5.3 1.6 2.0 3.5 4.7 4.8 0.4 0.8 14.9 5.5 3.6 0.2 23.3 1.3 5.6 11.5 13.0 7.3 3.5 4.2 5.4 5.6 2.5 1.4 4.1 6.4 7.5 6.1 2.9 1.0 0.3 2.4 3.9 0.5 5.2 0.2 1.7 0.2 0.6 2.0 0.2 0.1 2.4 1.1 1.3 0.3 1.5 0.3 0.0 4.8 2.0 1.7 0.2 0.7 6.2 7.4 10.8 6.4 7.5 7.5 2.6 4.5 3.9 3.8 8.6 4.6 13.7 6.4 7.0 26.8 1.5 29.7 6.9 9.5 13.1 15.4 6.8 12.4 7.9 17.2 10.7 7.3 14.6 4.9 6.0 16.5 1.9 6.3 5.3 6.4 12.2 11.9 9.0 0.0 62.5 6.3 2.5 17.4 6.6 5.7 0.0 2.2 11.7 12.1 5.4 11.8 63.4 12.9 8.2 7.3 18.9 2.1 9.9 5.7 10.6 33.7 7.2 3.3 6.2 84.9 34.1 7.6 10.0 11.3 5.2 7.7 23.7 5.8 10.2 9.4 32.9 8.3 10.9 18.2 14.1 14.4 29.8 5.3 5.9 2.9 11.7 11.8 ORC4 "HsORC4, ORC4L, Orc4p" ENSG00000115947 "Origin recognition complex subunit 4" O43929 2 147930396-148021604 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015124, HPA064562" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" "CAB015124: AB_2157883, HPA064562: AB_2685287" "unprognostic (5.04e-2)" "unprognostic (6.56e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (7.27e-4)" "unprognostic (8.28e-2)" "unprognostic (6.45e-2)" "prognostic unfavorable (4.98e-8)" "unprognostic (5.55e-2)" "unprognostic (8.00e-2)" "unprognostic (1.81e-2)" "unprognostic (4.92e-2)" "unprognostic (1.19e-1)" "prognostic favorable (4.10e-6)" "unprognostic (2.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.62e-1)" "unprognostic (1.95e-3)" 9.7 11.2 11.5 10.1 13.1 19.3 14.6 21.6 16.3 9.0 8.7 12.6 12.0 12.0 11.0 10.6 14.2 9.7 11.6 12.8 10.8 20.5 12.8 9.3 10.9 9.6 7.9 16.7 8.2 16.2 7.6 10.1 10.0 12.1 13.8 19.7 13.4 10.3 15.0 9.3 11.4 11.5 7.6 8.9 9.4 15.5 10.9 15.7 15.6 10.9 11.9 10.2 6.6 14.4 22.8 19.3 37.2 20.4 14.2 13.9 39.9 25.2 21.3 31.3 31.0 47.9 22.6 29.3 26.8 15.1 27.7 22.4 43.4 25.2 32.4 20.6 36.1 40.2 19.0 32.8 18.8 25.9 14.5 11.9 29.4 34.0 13.9 23.3 21.4 27.5 38.8 14.9 21.2 23.8 20.1 20.9 42.3 18.9 28.0 21.6 24.9 26.5 34.5 46.3 35.0 27.4 22.6 24.7 30.1 33.6 18.9 12.2 15.5 23.5 23.2 17.3 23.4 14.7 37.9 27.5 19.1 20.0 14.6 24.1 13.1 18.3 13.6 17.5 13.9 14.1 12.9 13.9 16.4 14.5 13.4 13.5 18.8 19.3 14.0 8.3 15.1 11.7 11.5 13.1 21.6 16.3 12.8 10.8 9.6 7.9 10.0 7.6 10.9 14.4 21.5 83.3 62.5 53.5 26.0 26.0 21.8 47.1 27.3 48.7 20.3 24.0 25.9 11.5 66.1 12.9 39.6 40.3 27.3 21.7 45.0 31.6 34.0 47.9 17.6 23.8 22.9 46.5 88.4 17.2 48.2 27.7 14.3 26.1 45.5 28.3 19.2 17.1 23.8 53.8 91.4 18.9 28.5 18.8 20.7 15.7 22.4 19.7 21.4 34.7 22.0 33.8 24.7 69.9 71.3 18.3 15.4 21.4 12.8 24.4 23.2 55.4 85.8 37.5 32.9 23.2 31.5 61.2 26.8 22.6 24.9 32.7 25.6 16.9 21.8 20.6 MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 317.4;Excitatory neurons: 510.1;Inhibitory neurons: 456.0;Microglial cells: 288.6;Oligodendrocyte precursor cells: 604.2;Oligodendrocytes: 438.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 10: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody" "HPA035964: AB_2674891" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (3.72e-4)" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (1.65e-1)" "unprognostic (9.86e-2)" "unprognostic (7.72e-2)" "unprognostic (2.00e-1)" "unprognostic (1.94e-1)" "unprognostic (2.39e-2)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (6.59e-2)" "unprognostic (1.82e-1)" 2.5 3.2 3.7 2.2 4.3 2.0 2.3 7.2 5.1 3.1 0.5 5.2 1.8 3.2 1.6 2.6 2.2 3.2 2.8 3.9 3.1 3.4 2.0 2.3 2.4 2.2 2.2 3.7 1.7 4.1 3.8 3.0 2.1 3.0 1.9 5.7 1.8 2.5 2.8 1.9 2.3 2.7 2.0 2.6 2.7 3.1 3.3 4.2 3.4 3.0 2.2 3.7 2.2 4.1 1.1 1.1 4.4 4.1 3.5 3.6 2.9 4.0 3.9 3.1 2.3 2.8 2.9 1.9 0.9 3.4 1.7 0.8 3.1 5.1 4.1 1.6 1.6 3.5 2.8 1.5 2.0 0.6 0.6 2.9 4.1 4.5 3.3 5.0 4.1 2.7 1.9 3.6 4.8 2.7 1.5 2.7 2.2 2.5 1.7 1.6 1.2 0.8 3.2 3.8 2.9 3.5 3.2 1.6 3.0 3.2 2.3 3.4 2.8 3.7 1.8 0.6 1.9 2.4 1.1 1.5 4.8 1.6 3.6 0.8 0.1 0.5 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.2 0.3 0.4 0.2 0.2 0.3 0.3 0.1 0.1 3.7 4.3 7.2 5.1 3.9 3.1 2.2 2.2 2.1 2.0 3.3 4.1 27.3 16.0 13.7 317.4 23.4 3.8 11.9 4.1 10.8 24.7 16.5 15.0 10.5 11.5 14.8 12.9 37.5 7.3 23.8 5.0 3.9 18.6 94.5 14.8 25.8 15.2 11.5 36.6 510.1 15.7 9.8 15.5 12.2 18.0 3.8 35.9 15.0 8.4 7.0 13.5 456.0 4.9 6.1 16.9 3.3 37.6 18.0 15.1 0.0 288.6 13.6 8.1 24.7 604.2 438.3 20.4 4.6 10.5 22.8 7.8 9.4 14.0 8.5 17.4 6.6 16.5 16.8 15.7 9.4 10.4 3.3 8.5 27.7 23.7 5.8 12.6 EPC2 DKFZP566F2124 ENSG00000135999 "Enhancer of polycomb homolog 2" Q52LR7 2 148644440-148787569 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 125.7;Oligodendrocytes: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036759 Uncertain Approved "Nuclear speckles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA036759: AB_10672365" "unprognostic (1.65e-1)" "unprognostic (1.24e-1)" "unprognostic (7.16e-2)" "unprognostic (2.83e-3)" "unprognostic (2.59e-2)" "unprognostic (1.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.47e-2)" "unprognostic (3.86e-2)" "unprognostic (2.29e-1)" "unprognostic (6.21e-2)" "unprognostic (5.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.54e-2)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (4.91e-2)" 16.4 14.0 9.6 13.5 10.9 50.3 17.2 22.0 13.4 18.2 7.8 12.4 9.7 25.5 14.1 12.2 15.3 15.3 15.5 9.9 11.3 12.9 12.7 14.6 18.0 9.6 9.9 31.9 9.8 12.1 9.9 18.5 9.9 16.2 13.9 14.0 11.5 15.5 15.9 11.7 10.5 19.1 9.7 15.9 12.0 14.2 11.5 23.1 19.3 18.5 15.9 15.6 14.0 14.5 9.2 7.0 23.8 14.8 15.7 19.5 17.9 15.9 21.4 25.3 21.2 14.1 12.0 19.8 7.8 18.7 10.9 12.1 20.7 12.7 31.1 17.6 15.4 38.9 11.0 19.8 16.0 29.7 22.7 20.5 22.1 25.8 25.3 15.6 15.9 15.9 20.9 33.4 16.0 14.7 20.2 19.8 24.3 8.7 13.6 20.7 22.1 18.2 12.7 25.6 32.5 23.6 19.6 12.0 29.8 16.6 7.7 25.8 19.2 20.2 17.7 14.0 13.6 20.3 17.0 25.0 16.0 17.4 21.9 0.1 0.9 1.2 0.9 0.7 1.3 0.8 1.4 0.8 0.9 0.8 1.5 1.1 4.5 0.3 2.0 1.0 1.4 0.5 9.6 10.9 22.0 13.4 9.9 11.3 9.6 9.9 9.9 9.7 11.5 14.5 24.2 25.6 13.6 60.1 21.1 14.0 26.4 4.8 4.0 19.6 15.4 17.1 22.0 8.6 15.1 9.2 6.2 11.3 27.5 8.4 3.9 9.1 28.5 23.5 25.9 17.0 18.0 15.8 79.2 8.8 11.7 20.7 8.6 27.3 6.3 15.6 7.9 5.0 8.6 8.4 75.3 9.2 2.0 16.1 10.2 5.5 23.9 17.7 12.4 70.3 11.3 14.1 20.6 125.7 99.3 9.3 9.1 23.0 10.7 20.3 6.3 6.7 9.8 15.7 13.1 44.4 25.4 19.3 18.6 7.8 15.6 20.1 25.2 16.3 8.1 23.6 KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 252.2;Early spermatids: 568.4;Excitatory neurons: 267.2;Inhibitory neurons: 249.1;Late spermatids: 702.5;Oligodendrocytes: 270.7" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" 0.5 5.1 41.3 0.6 17.6 0.0 0.5 13.9 65.2 1.4 0.0 1.1 0.3 0.5 3.7 0.1 0.9 0.1 0.6 28.9 13.7 0.2 0.0 0.2 0.3 15.4 9.0 1.6 2.3 0.3 5.5 0.0 24.6 10.4 0.6 7.8 0.2 2.8 0.3 0.3 0.8 0.4 16.3 0.2 0.6 12.1 49.8 0.1 1.3 0.9 0.2 0.6 1.4 32.0 0.0 0.0 17.8 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.0 0.7 0.0 0.2 5.4 0.0 14.1 0.0 1.3 13.7 3.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.7 0.0 0.7 0.0 0.1 0.0 0.8 0.0 0.0 22.4 0.0 9.2 0.0 0.1 0.1 0.0 3.6 117.1 27.1 0.2 0.5 0.2 2.8 0.0 0.0 0.0 0.0 3.3 0.0 3.7 3.0 0.4 0.0 8.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 17.6 13.9 65.2 28.9 13.7 15.4 9.0 24.6 16.3 49.8 32.0 1.8 0.0 0.0 33.6 2.4 1.3 6.1 0.1 2.2 252.2 8.0 3.7 14.9 4.3 0.0 18.4 108.4 0.0 0.8 1.1 0.0 0.3 568.4 0.9 1.6 6.1 129.7 0.0 267.2 0.0 0.1 4.9 2.0 0.2 0.0 1.1 0.7 0.0 0.2 99.3 249.1 2.7 4.1 0.3 1.9 702.5 8.1 0.8 5.4 10.3 0.8 8.5 2.1 125.2 270.7 0.9 3.4 12.8 1.7 35.8 0.1 0.1 0.0 15.1 6.6 1.6 9.1 15.8 10.7 0.2 0.4 0.0 11.9 0.3 4.9 2.3 LYPD6B "CT116, LYPD7" ENSG00000150556 "LY6/PLAUR domain containing 6B" Q8NI32 2 149038107-149215262 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 95.5" "Cell type enhanced" "Detected in many" "Early spermatids: 245.7;Gastric mucus-secreting cells: 87.7;Inhibitory neurons: 77.8;Late spermatids: 118.5;Suprabasal keratinocytes: 69.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 13.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 13.8" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 64.8;LHCN-M2: 102.3;NB-4: 34.7;RT4: 54.7;SK-BR-3: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049239 Uncertain "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "HPA049239: AB_2680688" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (8.42e-2)" "unprognostic (3.12e-3)" "unprognostic (1.64e-1)" "unprognostic (3.37e-1)" "unprognostic (2.01e-2)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-3)" "unprognostic (2.59e-2)" "unprognostic (4.40e-2)" "unprognostic (1.77e-2)" "unprognostic (1.45e-1)" "unprognostic (2.85e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-3)" 0.3 0.2 3.5 0.4 2.5 0.2 16.4 1.6 5.3 2.8 1.6 1.7 2.6 0.9 1.2 4.1 23.4 37.3 0.0 4.3 4.1 20.5 0.9 1.7 0.4 2.3 7.3 0.4 12.3 16.1 0.4 0.8 3.0 11.1 3.3 1.0 5.8 15.2 0.2 95.5 1.2 0.3 1.9 2.8 41.3 34.1 8.0 0.3 0.2 0.0 1.9 14.2 6.3 2.1 1.4 0.0 0.0 1.5 0.0 0.1 0.1 8.0 1.5 6.6 2.5 1.0 0.0 0.0 0.0 64.8 0.0 14.0 1.5 1.3 20.6 0.0 7.4 0.0 1.9 0.0 0.2 0.0 0.1 0.6 21.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 102.3 24.3 0.0 34.7 2.0 14.6 0.3 0.0 0.4 4.3 3.2 54.7 3.9 0.1 0.4 32.1 0.0 6.3 4.8 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.8 13.8 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.5 2.5 1.6 5.3 4.3 4.1 2.3 7.3 3.0 1.9 8.0 2.1 0.5 0.0 2.0 2.3 5.5 29.8 21.0 30.6 6.2 0.0 23.4 17.1 1.4 42.9 23.9 46.0 0.0 0.1 0.1 4.0 7.9 12.4 245.7 5.2 0.3 1.0 2.4 2.7 4.6 19.1 0.7 0.8 87.7 5.7 0.0 0.4 0.0 0.1 0.1 0.0 77.8 3.9 8.2 0.0 2.8 118.5 2.1 0.4 5.4 0.0 0.6 0.0 0.0 0.0 0.4 30.9 6.0 0.0 4.5 40.6 5.7 0.2 21.4 0.0 0.0 0.0 1.3 4.2 1.7 3.5 69.0 0.3 1.1 0.0 3.5 53.7 LYPD6 MGC52057 ENSG00000187123 "LY6/PLAUR domain containing 6" Q86Y78 2 149329985-149474138 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.0;placenta: 15.7" "Cell type enhanced" "Detected in many" "Astrocytes: 40.8;Early spermatids: 59.7;Inhibitory neurons: 65.9;Late spermatids: 230.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 37.6;fHDF/TERT166: 48.2;HBF TERT88: 25.0;LHCN-M2: 46.2;RT4: 39.9" "Low region specificity" "Detected in all" HPA042805 Enhanced Approved Cytosol "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA042805: AB_10794159" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (7.23e-3)" "unprognostic (1.64e-2)" "unprognostic (3.25e-1)" "unprognostic (6.49e-3)" "unprognostic (6.97e-3)" "unprognostic (1.72e-1)" "unprognostic (2.73e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.14e-3)" "unprognostic (6.75e-2)" "unprognostic (7.33e-4)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.72e-4)" 1.4 0.3 8.0 0.6 4.6 0.0 9.3 4.5 5.5 0.9 1.2 1.5 1.7 2.1 0.1 0.5 1.6 11.1 0.6 4.7 9.8 2.0 0.3 0.2 0.2 6.8 24.0 0.6 1.9 1.4 0.3 15.7 6.7 1.4 2.5 7.0 0.2 1.3 0.1 0.6 1.4 2.9 5.6 0.6 3.9 6.8 16.1 0.3 0.2 0.1 1.3 2.6 0.4 4.2 0.2 0.0 6.8 37.6 0.0 0.1 0.5 15.0 6.6 18.9 11.7 0.2 3.0 0.0 0.8 48.2 9.1 3.8 5.3 0.1 25.0 0.0 1.7 0.1 9.6 0.0 0.2 0.0 0.0 0.0 0.4 0.0 11.0 0.4 0.3 0.0 0.0 0.0 46.2 6.7 0.0 3.6 5.4 3.2 4.3 0.0 20.1 0.0 2.3 39.9 1.5 6.7 10.1 11.2 1.2 12.2 1.5 0.8 0.0 0.4 5.7 0.5 8.2 0.0 0.0 0.0 3.5 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 4.6 4.5 5.5 4.7 9.8 6.8 24.0 6.7 5.6 16.1 4.2 0.1 0.0 0.0 40.8 0.0 0.1 0.6 1.0 1.2 2.7 11.7 6.6 0.4 10.0 2.0 0.0 0.0 0.0 0.0 0.4 3.9 2.6 59.7 1.7 0.4 0.9 0.0 0.0 0.3 0.9 0.2 1.4 10.7 2.5 0.0 0.7 0.4 0.0 0.3 0.0 65.9 2.8 0.0 0.0 0.0 230.4 3.1 0.0 0.0 1.0 0.0 4.1 0.0 13.6 1.0 4.5 0.4 0.4 0.1 2.1 1.7 0.0 0.8 3.4 0.0 0.1 0.2 1.0 5.2 0.7 0.0 0.3 0.1 0.0 2.0 1.7 MMADHC "C2orf25, cblD, CL25022" ENSG00000168288 "Metabolism of cobalamin associated D" Q9H3L0 2 149569637-149587778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037531, HPA037532" Supported NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA037531: AB_10671628, HPA037532: AB_2675526" "unprognostic (5.67e-2)" "unprognostic (8.86e-2)" "unprognostic (1.98e-2)" "unprognostic (1.80e-3)" "unprognostic (1.15e-1)" "unprognostic (2.07e-3)" "unprognostic (8.17e-2)" "unprognostic (4.18e-3)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.14e-2)" "unprognostic (5.64e-2)" "unprognostic (2.14e-1)" "unprognostic (1.96e-1)" "unprognostic (3.54e-1)" "unprognostic (1.16e-1)" 64.9 62.5 32.0 53.0 33.3 144.3 96.7 36.1 40.7 71.0 38.9 78.0 66.4 68.3 55.5 88.7 64.6 58.0 113.9 32.9 34.7 97.1 195.1 53.7 75.3 33.8 33.0 67.6 86.9 91.7 38.6 76.5 34.5 76.7 90.1 37.8 86.0 69.5 201.2 85.5 62.1 79.0 35.5 56.2 68.7 70.4 34.3 88.8 65.8 187.8 93.3 85.7 57.6 36.9 124.8 90.8 113.9 282.4 134.4 222.9 173.9 198.7 262.0 204.8 175.1 174.8 135.3 199.0 109.5 214.0 121.1 156.7 160.8 203.2 257.5 134.9 130.4 159.0 111.0 193.4 218.0 241.0 145.6 180.2 204.4 265.7 273.1 190.3 233.8 130.5 216.2 205.3 245.0 134.7 106.3 151.8 163.6 168.5 182.9 129.2 130.5 170.9 219.4 209.6 144.0 80.4 148.4 135.4 196.7 122.7 139.6 133.4 160.1 162.5 153.4 120.8 155.2 130.1 177.2 213.9 159.5 143.9 220.6 183.5 77.1 129.6 75.0 87.4 88.3 103.2 94.0 83.4 113.8 85.2 98.4 81.5 150.0 119.7 106.0 96.3 124.0 119.8 32.0 33.3 36.1 40.7 32.9 34.7 33.8 33.0 34.5 35.5 34.3 36.9 50.3 48.1 57.4 12.1 78.3 131.7 183.9 262.2 106.4 24.7 64.2 70.0 162.8 80.1 147.3 49.7 12.5 150.4 63.2 76.7 201.5 148.8 179.9 68.6 48.0 77.5 97.4 156.5 14.7 186.0 178.7 86.5 82.6 53.5 66.0 47.5 79.9 135.6 129.5 20.2 21.1 128.2 166.8 101.9 69.3 46.4 66.5 67.2 78.2 11.2 93.8 55.9 87.6 18.1 19.1 154.5 80.1 78.2 125.8 177.3 95.9 215.0 143.2 19.2 98.6 74.3 89.7 223.0 53.6 114.2 141.5 245.0 68.1 90.3 87.1 237.0 RND3 "ARHE, Rho8, RhoE" ENSG00000115963 "Rho family GTPase 3" P61587 2 150468195-150539011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 155.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1633.3;Endometrial stromal cells: 521.7;Suprabasal keratinocytes: 924.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 680.9;BJ hTERT+: 1331.5;hTERT-HME1: 650.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060504 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA060504: AB_2684295" "unprognostic (8.03e-2)" "unprognostic (3.04e-2)" "unprognostic (2.36e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-3)" "unprognostic (4.23e-2)" "unprognostic (6.59e-2)" "unprognostic (1.27e-2)" "unprognostic (4.87e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (2.03e-2)" 58.0 50.0 12.1 27.8 8.6 1.2 99.2 8.6 9.2 47.8 8.1 27.2 16.8 45.2 7.3 155.4 14.0 59.9 23.6 8.8 10.2 14.6 131.9 23.2 11.4 8.5 8.4 8.4 16.2 1.9 7.8 46.4 18.4 46.0 27.1 5.2 28.9 37.7 14.4 50.5 19.9 62.3 7.1 39.5 20.2 4.7 14.2 8.2 7.4 14.0 24.5 108.8 44.1 7.0 46.5 27.5 49.2 93.8 137.1 65.7 0.4 680.9 1331.5 335.0 189.1 34.8 31.4 0.0 42.5 277.8 173.1 108.2 1.9 43.9 268.5 0.0 20.4 0.0 35.1 1.1 391.2 0.1 0.5 46.2 78.6 344.9 650.7 62.9 65.4 0.4 0.0 158.2 145.0 27.5 0.3 0.3 15.4 47.5 42.3 0.1 37.7 21.5 74.5 80.7 15.0 46.4 71.5 29.3 37.2 35.9 33.3 1.1 67.4 296.3 55.3 137.8 73.8 35.7 0.4 0.4 234.2 0.1 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 8.6 8.6 9.2 8.8 10.2 8.5 8.4 18.4 7.1 14.2 7.0 81.3 38.5 5.8 2.0 0.4 1633.3 231.2 304.7 368.2 40.5 131.9 218.1 95.6 45.8 192.5 9.2 14.6 71.7 1.8 359.8 3.9 63.4 1.9 389.9 521.7 46.3 32.8 5.3 0.6 14.6 12.8 353.4 56.6 400.3 4.5 0.6 26.4 129.3 12.2 1.7 35.3 130.5 97.6 76.8 83.0 2.2 10.5 12.0 136.9 15.0 0.0 9.6 0.0 0.5 0.5 107.4 249.5 10.5 4.6 102.4 174.8 3.9 157.0 2.7 19.7 182.0 166.8 0.9 3.4 458.0 924.7 91.1 10.9 36.8 117.5 262.9 RBM43 "C2orf38, FLJ45645" ENSG00000184898 "RNA binding motif protein 43" Q6ZSC3 2 151247940-151261863 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 20.4;HSkMC: 18.5" "Low region specificity" "Detected in all" HPA038204 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA038204: AB_10669520" "unprognostic (3.50e-2)" "unprognostic (5.45e-2)" "unprognostic (2.41e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-1)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (9.72e-3)" "unprognostic (2.57e-2)" "unprognostic (3.43e-3)" "unprognostic (1.22e-2)" "unprognostic (3.07e-2)" "unprognostic (1.12e-2)" "unprognostic (9.94e-2)" 5.2 8.7 2.4 4.2 2.3 6.7 6.9 1.6 2.3 7.5 3.5 4.2 3.0 7.6 9.4 3.2 12.3 6.8 3.2 2.1 2.7 7.0 6.7 6.1 6.9 2.9 2.9 15.4 4.0 5.1 2.9 5.7 2.3 6.5 4.4 1.8 5.2 7.7 3.4 4.7 3.9 5.7 2.8 7.9 4.6 3.6 2.9 7.0 12.3 2.5 4.7 3.8 3.1 3.0 3.5 2.2 3.5 4.7 9.4 20.4 2.3 4.0 9.2 5.0 7.2 0.1 5.7 2.7 1.5 7.3 2.7 1.7 1.1 4.6 2.5 4.2 2.5 6.6 1.0 0.2 9.1 8.2 2.2 18.5 5.0 4.0 3.0 7.4 10.7 2.9 2.7 3.0 6.8 3.5 4.7 3.9 1.3 0.1 4.2 3.2 4.1 1.6 8.4 3.0 1.3 4.2 3.8 2.8 7.8 0.6 4.1 5.2 6.1 3.7 3.3 3.2 1.7 1.1 0.8 0.0 9.7 3.3 2.3 1.0 0.7 3.0 1.2 0.9 2.0 1.2 1.6 1.5 0.5 1.3 2.0 1.5 0.8 2.7 2.4 0.2 0.8 0.6 2.4 2.3 1.6 2.3 2.1 2.7 2.9 2.9 2.3 2.8 2.9 3.0 26.5 3.2 8.9 2.9 9.6 3.3 3.2 5.8 5.7 6.7 8.6 14.9 2.6 11.5 5.7 18.4 0.0 6.8 8.4 1.7 27.4 6.8 3.0 30.9 17.2 16.9 6.1 8.8 1.0 5.9 4.7 21.8 5.6 9.4 3.8 13.4 20.7 9.1 5.1 6.7 1.3 6.9 4.1 10.4 4.3 2.4 28.0 8.2 3.6 2.8 12.3 22.1 13.4 4.0 0.9 4.6 5.6 29.0 5.5 2.8 5.5 18.2 26.3 1.3 0.0 18.4 13.0 0.5 3.6 7.3 3.1 1.4 13.5 30.4 3.7 2.2 NMI ENSG00000123609 "N-myc and STAT interactor" Q13287 2 151270470-151289894 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 207.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008588 Approved Supported Nucleoplasm,Cytosol "Secreted to blood" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "HPA008588: AB_1079493" "unprognostic (5.28e-2)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.42e-2)" "unprognostic (1.08e-1)" "unprognostic (4.51e-3)" "prognostic unfavorable (3.54e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.57e-7)" "unprognostic (1.91e-1)" "unprognostic (4.69e-2)" "unprognostic (1.52e-2)" "unprognostic (4.57e-2)" 20.6 15.7 7.3 44.5 7.1 74.5 23.3 7.0 10.4 15.2 7.4 25.9 33.7 13.9 16.6 19.0 19.8 24.0 7.5 7.1 7.7 14.0 35.5 28.6 43.4 8.6 7.7 16.8 7.8 6.3 4.2 34.2 8.2 13.2 26.7 1.4 20.2 17.2 4.8 19.4 33.8 20.9 8.2 47.5 24.9 6.6 7.9 44.4 16.9 8.3 33.5 27.9 10.5 8.2 53.2 25.7 1.3 0.0 14.4 39.4 49.3 14.6 36.8 74.1 112.0 5.9 119.9 51.0 55.4 23.5 24.5 29.6 5.6 13.8 18.6 110.0 3.0 144.9 27.3 3.1 63.1 139.9 40.2 25.7 18.3 44.1 10.0 32.1 91.8 56.4 74.0 12.6 14.4 41.6 116.4 207.7 29.5 10.9 37.6 125.5 2.9 45.8 60.9 46.1 7.4 0.3 32.0 35.1 20.5 5.1 5.6 157.9 47.5 10.5 23.3 33.8 22.3 1.8 2.0 3.2 24.5 166.4 11.3 251.3 121.3 140.5 62.7 172.8 74.3 64.8 66.1 63.4 108.8 58.5 52.1 54.3 466.8 98.1 170.0 43.3 62.3 104.3 7.3 7.1 7.0 10.4 7.1 7.7 8.6 7.7 8.2 8.2 7.9 8.2 37.3 25.6 24.9 2.9 22.9 16.7 21.1 47.0 15.4 0.3 13.8 15.1 7.0 18.6 35.6 12.9 0.0 76.4 33.4 21.4 15.6 66.6 3.4 36.2 9.0 41.1 18.0 55.5 0.4 41.1 69.4 19.1 15.3 23.8 36.1 17.7 27.5 17.8 80.2 0.0 0.2 25.1 8.2 49.7 25.6 1.7 19.6 51.5 1.8 12.2 86.5 7.4 57.7 5.0 0.7 40.2 34.5 13.9 12.9 19.1 35.3 35.3 47.4 0.1 6.6 11.7 15.2 3.6 2.2 19.4 17.8 54.5 36.2 23.1 24.9 23.3 TNFAIP6 "TSG-6, TSG6" ENSG00000123610 "TNF alpha induced protein 6" P98066 2 151357592-151380046 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "urinary bladder: 196.0" "Cell type enhanced" "Detected in many" "Early spermatids: 443.9;Fibroblasts: 302.3;Langerhans cells: 137.4;Melanocytes: 74.7" "Cancer enhanced" "Detected in many" "renal cancer: 27.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "neutrophil: 183.0" "Lineage enriched" "Detected in many" 22 "granulocytes: 183.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 67.5;HHSteC: 40.3;hTEC/SVTERT24-B: 54.9;SH-SY5Y: 21.6;U-2197: 44.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB032719, HPA050884" Uncertain "Secreted to blood" NA NA 100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB032719: AB_2204650, HPA050884: AB_2681261" "unprognostic (1.31e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (8.66e-2)" "unprognostic (2.51e-2)" "unprognostic (1.15e-3)" "unprognostic (3.26e-3)" "unprognostic (3.75e-4)" "unprognostic (4.49e-3)" "unprognostic (1.22e-1)" "unprognostic (1.90e-1)" "unprognostic (5.87e-3)" "unprognostic (1.08e-1)" "prognostic unfavorable (5.59e-4)" "unprognostic (1.06e-2)" "unprognostic (1.25e-2)" "unprognostic (5.46e-2)" "prognostic unfavorable (9.16e-5)" 15.6 0.5 1.9 27.6 2.2 7.6 11.1 1.5 2.8 9.2 1.2 6.3 0.7 2.0 0.3 2.2 2.2 19.8 15.4 1.7 2.2 0.4 1.2 11.0 0.6 1.6 2.2 0.5 1.2 0.3 0.4 1.8 1.9 3.2 2.8 0.0 3.4 0.9 1.7 2.7 2.2 7.2 1.6 3.0 4.0 10.6 2.6 1.4 1.6 2.8 0.5 196.0 1.6 2.3 0.0 0.0 0.0 0.0 3.8 15.5 0.0 2.5 67.5 2.5 12.4 0.0 0.0 0.0 0.8 1.1 1.4 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.3 0.0 40.3 0.0 0.0 19.5 0.0 54.9 3.8 2.3 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.3 0.0 15.5 0.0 1.1 0.0 0.0 0.0 0.0 21.6 0.5 0.0 0.0 0.4 0.0 0.0 0.0 2.2 4.4 44.3 0.8 0.0 0.0 0.0 4.8 0.7 3.3 0.0 8.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 183.0 0.0 2.1 0.0 0.0 2.5 1.9 2.2 1.5 2.8 1.7 2.2 1.6 2.2 1.9 1.6 2.6 2.3 4.5 3.2 1.7 1.3 1.1 64.7 0.9 11.1 0.0 0.0 1.5 1.4 2.2 0.0 1.5 0.0 0.0 0.1 0.3 0.1 0.0 2.8 443.9 2.9 2.7 7.3 0.0 0.8 0.7 0.0 0.9 302.3 0.5 10.6 2.5 0.0 1.4 0.0 1.4 0.0 0.4 0.0 0.0 6.9 137.4 38.5 2.5 49.6 74.7 1.9 5.9 0.0 0.0 13.6 7.1 1.5 0.0 0.4 1.4 3.0 0.0 0.2 0.2 0.0 0.0 40.6 45.5 10.7 1.9 1.0 53.0 1.8 6.0 0.3 0.0 3.8 RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036887, HPA036888" Supported Uncertain "Nucleoplasm,Nuclear bodies,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA036887: AB_2675361, HPA036888: AB_2675362" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.71e-1)" "unprognostic (4.71e-3)" "unprognostic (5.87e-2)" "unprognostic (1.79e-2)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-2)" "unprognostic (2.84e-2)" "unprognostic (1.80e-3)" "unprognostic (4.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.41e-2)" 6.1 5.0 4.4 7.4 8.4 21.7 10.0 13.8 7.0 6.5 2.6 5.6 4.3 8.2 4.0 5.6 5.6 5.6 3.5 4.6 5.1 5.5 6.7 5.1 8.5 4.4 5.1 11.2 7.0 6.8 3.5 8.0 5.4 6.0 6.1 8.2 7.7 5.0 7.5 7.2 4.6 6.2 4.9 6.5 6.1 11.0 4.5 10.7 9.1 9.5 7.9 7.3 4.6 13.8 20.8 17.4 26.8 20.5 10.7 13.8 25.9 24.8 18.0 21.6 25.5 28.9 16.4 39.2 21.7 17.3 17.9 21.3 41.2 17.1 36.1 27.8 19.8 63.4 21.4 21.0 11.2 64.7 20.2 10.3 11.3 38.8 28.7 12.3 21.3 23.5 52.2 32.6 22.1 13.8 38.3 22.9 43.2 11.2 22.9 38.4 42.1 26.1 11.6 24.9 24.2 18.8 32.0 14.6 16.5 18.8 12.9 23.1 27.0 32.9 22.8 20.3 26.7 16.0 29.6 55.4 15.3 25.5 22.5 6.3 2.5 3.0 4.3 1.7 4.9 4.0 3.6 3.2 1.8 3.1 4.8 3.7 2.8 7.7 3.5 1.6 2.8 1.7 4.4 8.4 13.8 7.0 4.6 5.1 4.4 5.1 5.4 4.9 4.5 13.8 53.1 96.1 49.7 41.1 43.5 49.3 47.5 21.9 33.0 48.2 30.4 29.8 38.2 28.6 38.0 14.7 31.3 39.2 40.3 19.6 1.9 38.5 22.6 38.0 61.7 48.0 25.0 84.3 68.5 21.9 35.9 51.3 34.7 65.0 34.1 88.6 27.1 19.7 23.0 47.1 72.4 30.9 14.2 26.4 27.0 14.0 43.8 37.6 30.2 48.7 44.1 35.8 32.0 73.9 126.3 29.9 23.5 34.3 45.1 53.2 14.9 12.9 21.3 42.8 85.5 106.5 51.2 122.8 113.1 28.9 41.6 40.9 45.3 58.9 34.6 45.4 NEB "NEB177D, NEM2" ENSG00000183091 Nebulin P20929 2 151485336-151734487 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 69 "skeletal muscle: 9300.2;tongue: 2495.6" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 662.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 8.8;RH-30: 34.3;U-266/70: 12.8" "Group enriched" "Detected in some" 6 "cerebellum: 6.5;olfactory bulb: 4.0" "Region enriched" "Detected in some" 6 "cerebellum: 11.8" HPA016601 Enhanced NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "HPA016601: AB_1854361" "unprognostic (2.40e-2)" "unprognostic (6.71e-2)" "unprognostic (2.13e-2)" "unprognostic (2.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.85e-3)" "unprognostic (2.54e-2)" "unprognostic (1.45e-1)" "unprognostic (4.41e-2)" "unprognostic (1.73e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (4.45e-13)" "unprognostic (6.80e-2)" "unprognostic (2.22e-2)" "unprognostic (4.07e-3)" "unprognostic (4.06e-2)" 2.3 6.4 2.2 0.7 5.0 1.3 2.9 4.0 2.6 0.5 1.4 1.3 1.1 0.6 1.6 16.2 0.5 12.7 40.7 2.2 5.4 3.3 4.9 2.3 1.3 2.9 2.9 0.9 2.0 0.1 2.6 0.8 2.4 22.1 0.1 3.5 85.9 0.2 9300.2 9.3 1.8 0.2 2.0 3.0 1.1 1.7 2.9 1.1 13.0 2495.6 0.8 0.4 1.2 2.9 0.5 0.5 0.8 0.7 0.1 0.1 2.3 0.4 0.0 0.0 0.0 6.1 0.7 1.7 1.2 0.1 0.2 1.2 0.1 0.0 0.0 0.8 0.9 0.6 1.1 2.0 0.0 1.1 1.5 5.0 0.3 0.1 0.0 0.3 0.8 0.5 1.2 8.8 0.5 0.7 0.6 1.1 1.4 3.0 1.0 1.6 34.3 0.2 0.1 1.2 2.0 0.3 0.3 0.4 0.2 1.3 0.9 1.1 0.8 0.9 1.2 0.1 1.2 12.8 2.0 0.4 0.2 0.8 1.5 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.2 5.0 4.0 2.6 2.2 5.4 2.9 2.9 2.4 2.0 2.9 2.9 0.3 0.0 1.1 14.0 2.0 0.8 1.2 0.2 2.8 2.4 0.5 0.4 82.6 18.6 0.7 0.0 0.0 0.5 1.2 0.0 0.0 0.5 7.6 1.4 1.5 2.1 1.8 0.0 13.1 0.0 0.4 10.6 2.0 2.5 1.3 2.2 0.7 2.4 0.7 3.3 9.2 0.0 4.1 1.3 0.7 7.6 0.6 2.7 0.0 7.5 0.2 0.4 0.0 6.0 5.2 0.1 0.0 0.0 2.0 1.1 0.3 0.4 0.1 1.7 0.0 662.8 1.9 1.4 1.6 0.2 1.3 0.8 1.1 1.5 0.0 0.2 ARL5A ARL5 ENSG00000162980 "ADP ribosylation factor like GTPase 5A" Q9Y689 2 151788984-151828492 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 88.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 88.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027002 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA027002: AB_10601685" "unprognostic (1.12e-2)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (9.36e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (6.04e-2)" "unprognostic (4.59e-2)" "unprognostic (4.61e-3)" "unprognostic (2.47e-1)" "unprognostic (1.40e-1)" "unprognostic (2.95e-3)" "unprognostic (2.97e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (2.55e-1)" 20.4 20.9 13.1 13.1 14.9 11.8 19.7 17.1 12.4 14.7 12.1 17.6 22.1 14.1 7.3 23.9 14.6 17.2 35.8 12.8 18.5 25.1 22.4 20.0 20.3 18.5 14.7 15.3 15.9 17.9 7.5 23.6 17.3 17.2 16.6 17.6 15.5 13.6 32.5 28.8 20.5 18.0 17.7 14.6 17.7 6.3 14.4 17.5 29.6 36.5 24.6 18.3 11.2 18.8 20.2 20.2 29.0 25.7 20.9 35.6 39.1 34.7 26.8 24.8 30.0 59.5 24.7 66.9 36.4 37.2 18.6 12.8 34.6 26.7 40.0 40.4 31.6 73.6 21.9 77.8 28.8 74.0 39.5 27.9 39.3 34.0 36.4 33.3 34.7 41.1 55.7 78.0 26.5 23.4 63.1 29.3 36.8 24.7 21.5 28.5 40.1 27.6 35.7 33.6 13.0 27.0 21.1 21.8 29.5 34.3 17.0 44.0 28.5 19.6 24.1 18.8 37.7 39.3 47.6 64.6 34.7 50.4 34.7 88.3 7.9 8.9 6.9 6.1 6.5 11.0 6.1 8.6 11.2 15.2 6.6 5.1 3.8 7.4 4.7 6.7 7.9 4.5 13.1 14.9 17.1 12.4 12.8 18.5 18.5 14.7 17.3 17.7 14.4 18.8 18.1 57.7 38.6 28.7 104.3 138.7 122.6 120.7 64.3 62.6 24.4 12.6 109.8 91.5 60.6 14.7 14.6 84.3 46.2 44.3 45.0 55.3 11.9 15.3 17.2 62.9 75.6 66.3 29.8 59.9 153.1 79.6 51.5 12.1 48.2 17.9 77.8 76.6 128.0 116.1 31.9 64.3 126.1 135.8 154.7 13.8 74.6 82.9 81.8 51.5 97.5 64.1 132.8 34.7 23.8 52.6 44.1 82.4 160.7 167.4 166.8 42.9 60.3 61.9 72.3 85.9 60.4 72.6 65.0 103.9 163.7 143.0 63.6 9.2 72.7 135.9 CACNB4 EJM4 ENSG00000182389 "Calcium voltage-gated channel auxiliary subunit beta 4" O00305 2 151832771-152099167 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 16.4;skin 1: 7.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 495.6;Inhibitory neurons: 470.7;Microglial cells: 136.8;Oligodendrocyte precursor cells: 155.3" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "neutrophil: 3.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.4" "Cell line enhanced" "Detected in some" "Hep G2: 4.1;HMC-1: 20.2;U-937: 5.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015601 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 6: Brain - Smell perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA015601: AB_1845873" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-1)" "unprognostic (1.49e-2)" "unprognostic (3.70e-1)" "unprognostic (9.42e-4)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.55e-2)" "unprognostic (7.26e-3)" "unprognostic (3.93e-2)" "unprognostic (9.55e-3)" "unprognostic (2.45e-1)" 0.7 0.7 4.6 0.4 12.0 0.7 1.5 15.2 16.4 0.4 1.3 0.3 0.4 0.4 0.6 1.4 0.3 0.9 0.3 6.2 2.3 1.4 0.1 2.0 0.3 0.2 5.6 0.3 0.4 0.4 1.8 0.9 0.3 2.0 0.5 1.8 1.7 1.9 0.1 7.3 0.3 0.5 0.3 0.4 0.6 2.3 6.8 1.1 1.4 0.2 1.0 2.0 0.5 6.8 0.0 0.0 0.7 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.9 0.0 1.9 0.0 0.1 0.3 3.2 0.0 0.2 4.1 0.0 0.2 20.2 0.2 0.1 0.4 0.0 1.7 0.0 0.8 0.0 0.5 0.1 0.0 0.2 0.3 0.5 0.1 0.6 2.0 0.2 0.6 1.1 0.5 1.3 0.7 0.0 0.0 0.0 0.1 3.3 0.8 0.0 1.8 2.0 0.6 0.4 0.3 0.0 0.0 0.4 5.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 3.4 0.0 0.0 0.6 0.0 0.1 4.6 12.0 15.2 16.4 6.2 2.3 0.2 5.6 0.3 0.3 6.8 6.8 1.1 12.8 53.3 80.6 0.8 12.4 16.3 3.5 30.7 9.9 6.8 7.2 1.3 0.0 3.8 3.7 4.2 0.1 0.3 0.3 3.9 0.5 0.9 3.0 3.0 1.3 0.0 0.0 495.6 1.5 0.0 7.9 1.1 5.4 0.0 84.1 0.7 0.0 3.4 20.2 470.7 0.0 0.0 1.2 7.5 2.1 3.4 2.4 1.8 136.8 1.2 2.3 1.0 155.3 31.2 1.0 0.1 4.5 2.0 29.0 0.1 0.9 1.2 3.4 0.0 0.6 1.2 0.7 4.1 3.2 8.2 0.0 1.1 6.6 0.1 16.3 STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA035528: AB_10601606, HPA035529: AB_10672868" "unprognostic (1.53e-1)" "unprognostic (1.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (7.92e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" 9.7 9.9 7.3 7.9 8.3 3.1 12.5 7.5 8.9 10.9 8.0 10.3 9.3 10.9 8.7 9.1 12.8 9.3 9.6 6.3 7.7 14.6 11.0 10.8 8.7 7.5 7.9 11.0 8.8 12.8 6.5 10.3 7.9 12.9 10.9 11.1 11.9 8.9 5.8 10.8 9.3 10.1 8.0 8.3 11.7 12.6 7.4 8.5 14.3 7.7 8.9 10.7 6.6 9.7 8.3 7.9 7.2 8.8 18.5 22.0 7.7 16.8 19.4 10.7 13.6 7.8 7.8 10.8 13.1 24.2 9.4 8.3 8.0 15.6 17.1 13.3 6.3 7.8 5.1 11.8 21.2 11.5 14.6 16.9 14.6 20.0 26.8 15.5 11.7 7.2 5.1 7.5 22.2 8.1 6.1 8.9 4.5 6.1 11.2 4.9 8.9 5.9 16.7 14.1 3.8 5.9 9.3 8.2 14.1 8.0 11.1 10.5 15.3 23.7 7.6 18.8 10.3 6.1 6.7 6.8 17.9 9.2 13.2 16.8 3.4 4.6 1.7 4.6 1.6 1.7 1.8 1.9 2.7 2.0 1.5 1.9 8.6 2.6 7.1 3.2 2.2 1.6 7.3 8.3 7.5 8.9 6.3 7.7 7.5 7.9 7.9 8.0 7.4 9.7 17.6 25.6 33.5 39.2 10.9 13.8 12.0 16.4 15.9 10.6 17.9 11.6 30.5 7.2 28.9 16.5 16.7 7.4 14.7 22.1 23.5 13.9 147.8 37.2 25.5 15.1 8.3 13.5 43.8 14.2 14.6 22.7 27.0 22.2 27.1 14.8 17.5 16.0 16.7 1.7 39.7 20.2 20.3 20.0 13.0 64.4 15.8 16.9 14.2 32.8 19.6 14.7 8.2 51.8 61.0 21.2 18.2 15.4 10.9 14.3 13.9 14.8 55.6 11.6 26.3 18.0 16.1 54.1 20.1 13.5 13.2 20.2 9.3 18.2 13.5 16.1 FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 223.5" "Cell type enhanced" "Detected in many" "Astrocytes: 668.0;Excitatory neurons: 574.9;Inhibitory neurons: 321.9;Oligodendrocyte precursor cells: 371.0;Oligodendrocytes: 2442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 5 "monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 191.4;hTERT-HME1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: AB_1848965" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.75e-3)" "unprognostic (3.06e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.54e-1)" "unprognostic (4.66e-2)" "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" 26.4 25.2 88.9 11.1 152.3 0.7 20.8 135.2 119.3 18.1 73.6 15.2 8.9 20.7 14.9 8.5 15.3 16.8 12.0 92.9 102.6 22.2 8.1 32.2 14.2 172.3 136.3 54.0 18.1 23.1 28.4 58.2 165.5 15.2 12.3 10.6 32.1 11.7 24.1 11.3 11.6 16.3 121.6 19.8 17.3 9.0 128.5 14.8 33.1 19.3 8.4 19.3 18.3 223.5 14.5 15.1 45.9 25.5 54.5 58.3 191.4 14.4 29.4 24.9 34.8 16.3 0.9 0.3 29.8 12.6 53.7 16.2 22.4 45.8 39.6 0.1 23.4 0.2 10.0 70.2 15.7 4.0 0.8 38.4 27.8 48.2 123.5 48.3 44.7 6.6 0.6 0.3 13.9 4.0 0.8 4.5 29.5 12.4 30.0 25.9 9.9 20.9 72.9 9.9 46.6 38.0 12.2 4.5 51.4 38.7 1.1 1.5 49.9 37.4 1.0 12.7 25.0 1.3 0.5 0.1 34.7 3.3 77.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 88.9 152.3 135.2 119.3 92.9 102.6 172.3 136.3 165.5 121.6 128.5 223.5 21.5 25.6 25.9 668.0 2.7 26.4 23.0 14.0 19.4 23.8 11.4 10.0 3.8 1.5 16.4 11.0 0.0 36.1 4.5 2.6 13.7 20.4 24.5 14.1 10.8 29.1 8.3 0.4 574.9 6.9 17.8 36.2 8.2 27.0 1.3 36.0 20.0 1.3 40.6 0.0 321.9 3.3 10.2 64.8 53.0 10.5 35.1 31.5 7.2 245.4 4.4 3.9 1.0 371.0 2442.0 10.0 2.1 41.3 5.6 33.5 0.7 8.9 8.5 2.0 6.6 18.7 13.2 6.7 8.0 6.3 16.9 27.0 2.1 13.0 6.1 13.2 PRPF40A "FBP-11, FBP11, FLAF1, FLJ20585, FNBP3, HIP10, HYPA, NY-REN-6, Prp40" ENSG00000196504 "Pre-mRNA processing factor 40 homolog A" O75400 2 152651593-152717997 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038272, HPA038273" Approved Enhanced "Nuclear speckles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA038272: AB_2675923, HPA038273: AB_10671526" "unprognostic (1.81e-1)" "unprognostic (2.91e-1)" "unprognostic (4.31e-3)" "unprognostic (4.49e-3)" "unprognostic (1.55e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.62e-2)" "unprognostic (3.61e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (1.58e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.89e-4)" "unprognostic (1.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.24e-2)" "unprognostic (2.05e-2)" 16.7 16.7 9.0 24.7 9.8 45.0 21.5 14.3 10.4 16.8 9.4 24.2 23.0 18.6 15.7 27.6 18.0 17.4 15.3 8.7 10.3 18.9 21.7 17.4 30.4 10.4 8.7 18.9 19.7 24.0 10.5 22.2 10.9 18.4 20.9 16.7 16.6 15.0 22.8 21.0 23.0 17.4 9.9 20.7 22.2 25.5 8.7 31.5 24.6 20.0 28.1 27.1 15.1 12.3 63.4 62.9 68.9 70.8 39.1 51.8 95.5 61.8 55.2 86.0 78.9 120.0 57.8 130.9 88.0 62.7 49.2 63.8 90.8 74.3 91.6 72.4 78.6 121.8 55.7 79.9 50.7 135.4 81.6 41.7 61.9 113.8 127.3 52.4 67.5 60.8 133.2 60.6 52.9 38.4 57.2 63.4 102.9 41.2 75.8 110.4 73.3 86.9 43.7 99.8 82.2 56.0 73.9 53.5 67.6 50.6 46.8 85.4 79.1 90.3 56.6 51.9 81.4 38.8 67.7 130.6 57.9 78.2 56.1 87.6 70.1 91.7 66.7 86.5 62.3 65.5 62.1 60.7 79.4 70.3 65.5 58.8 61.1 70.4 101.1 84.8 58.8 80.1 9.0 9.8 14.3 10.4 8.7 10.3 10.4 8.7 10.9 9.9 8.7 12.3 98.5 112.2 118.5 48.3 120.3 141.0 120.0 117.9 101.3 65.0 73.6 70.6 64.4 55.8 122.1 53.3 73.0 123.1 123.7 67.2 49.0 110.0 150.3 101.0 126.6 97.4 78.3 105.6 56.4 111.5 155.9 96.4 74.9 121.0 123.4 111.0 53.9 72.5 109.2 60.6 53.3 81.5 87.5 95.7 114.5 36.4 69.3 125.5 55.2 44.0 184.1 62.7 107.1 44.7 71.3 128.3 86.8 79.7 112.1 131.7 69.5 75.7 152.6 75.2 98.6 104.8 132.1 239.0 121.4 141.6 151.7 132.2 119.9 164.9 103.7 148.4 ARL6IP6 MGC33864 ENSG00000177917 "ADP ribosylation factor like GTPase 6 interacting protein 6" Q8N6S5 2 152717893-152762396 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 155.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 214.0;eosinophil: 161.8" "Lineage enriched" "Detected in all" 9 "granulocytes: 214.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014743 Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nuclear membrane" Cytosol "HPA014743: AB_1845030" "unprognostic (4.41e-1)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "unprognostic (9.86e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (5.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.00e-3)" "unprognostic (4.95e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.14e-1)" "unprognostic (2.67e-1)" "unprognostic (4.57e-1)" "unprognostic (7.39e-2)" 5.1 3.9 3.0 1.8 4.0 8.3 4.7 3.2 3.0 4.4 2.2 3.7 2.4 4.2 1.2 6.0 3.8 1.2 2.7 2.6 3.1 2.5 1.9 4.0 3.4 3.9 3.3 5.0 2.7 1.1 3.1 4.4 4.3 3.1 1.9 3.2 3.9 1.8 3.5 7.1 3.5 1.6 3.6 4.4 3.1 5.3 3.3 3.9 3.2 2.0 2.4 4.2 5.5 5.3 9.6 6.2 13.7 3.9 4.1 4.6 19.7 11.6 4.9 9.6 12.2 14.2 13.3 17.2 10.6 5.2 4.3 10.7 8.1 5.7 10.4 26.1 15.1 14.2 5.3 13.0 4.5 12.1 12.4 3.3 6.5 10.6 8.9 3.4 7.5 11.9 14.9 10.6 7.8 7.1 12.1 12.6 13.3 3.2 12.7 13.0 13.4 13.9 4.5 7.2 11.6 12.0 10.4 1.1 9.7 4.7 4.7 7.9 10.0 14.4 9.9 10.2 10.3 9.9 10.3 13.1 6.8 10.4 12.3 214.0 9.1 161.8 13.2 10.2 13.2 20.3 13.3 13.5 10.9 18.4 13.6 11.4 24.8 9.7 12.8 24.8 19.7 13.2 3.0 4.0 3.2 3.0 2.6 3.1 3.9 3.3 4.3 3.6 3.3 5.3 34.3 16.0 10.0 30.7 41.9 106.6 48.5 74.0 50.7 6.3 20.3 14.9 4.3 17.2 29.9 11.0 4.2 155.7 42.4 14.1 17.6 24.9 14.1 17.7 20.0 31.3 13.8 81.0 21.0 18.6 136.2 27.9 30.1 25.0 27.3 19.4 28.5 5.9 39.8 8.4 23.8 22.2 38.7 24.2 57.2 24.2 19.6 33.6 46.2 30.9 46.2 19.8 32.0 38.7 56.8 22.5 18.6 17.0 33.8 40.3 16.3 8.8 29.2 15.8 32.9 22.2 24.9 24.4 30.0 43.4 106.6 108.4 45.2 27.9 24.5 51.3 RPRM "FLJ90327, REPRIMO" ENSG00000177519 "Reprimo, TP53 dependent G2 arrest mediator homolog" Q9NS64 2 153477338-153478762 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 13.7;Endometrial stromal cells: 63.3;Fibroblasts: 16.3;Sertoli cells: 13.1;Theca cells: 50.4" "Cancer enriched" "Detected in many" 4 "testis cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HEK 293: 25.9;MCF7: 29.8;NTERA-2: 20.5;SCLC-21H: 7.5;SH-SY5Y: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 36: Stromal cells - Cell proliferation" "unprognostic (6.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-1)" "unprognostic (1.62e-2)" "unprognostic (5.19e-1)" "unprognostic (5.51e-2)" "unprognostic (3.09e-3)" "unprognostic (2.58e-1)" "unprognostic (6.19e-2)" "unprognostic (6.38e-4)" "unprognostic (5.21e-2)" "unprognostic (1.25e-2)" "unprognostic (8.61e-2)" 5.6 16.2 12.2 0.1 8.1 0.0 0.4 2.4 8.0 25.9 11.6 18.0 0.1 22.9 2.0 0.5 3.9 0.0 0.3 6.1 22.9 2.7 0.0 0.7 0.0 9.9 7.5 17.9 0.0 1.0 19.6 0.1 6.7 12.7 0.4 1.3 11.2 6.4 0.2 1.1 0.6 12.2 5.6 2.0 9.3 1.1 9.5 0.1 1.2 0.2 0.0 3.1 3.2 6.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.0 0.0 25.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 29.8 0.0 0.0 20.5 0.0 1.1 0.0 0.0 0.1 0.0 0.2 7.5 8.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 12.2 8.1 2.4 8.0 6.1 22.9 9.9 7.5 6.7 5.6 9.5 6.4 0.9 3.2 0.0 0.0 0.0 0.1 0.8 1.3 1.2 7.8 0.8 2.2 0.5 2.8 1.6 1.8 0.0 0.3 0.0 0.0 13.7 0.0 0.5 2.2 63.3 0.9 1.8 0.0 3.2 1.7 0.4 16.3 1.1 1.0 0.0 2.9 0.0 0.0 0.6 0.0 3.1 0.0 10.2 0.0 0.3 0.8 0.9 0.5 0.0 1.0 0.0 0.8 0.0 3.0 0.3 0.4 0.0 0.7 0.0 1.6 0.0 0.5 1.1 1.8 13.1 0.7 4.0 0.6 5.2 2.2 0.3 0.8 0.3 50.4 0.0 1.4 GALNT13 "GalNAc-T13, KIAA1918" ENSG00000144278 "Polypeptide N-acetylgalactosaminyltransferase 13" Q8IUC8 2 153871922-154453979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;retina: 9.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 214.6;Inhibitory neurons: 333.1;Oligodendrocyte precursor cells: 986.7;Oligodendrocytes: 398.2" "Cancer enriched" "Detected in some" 5 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 43.8;U-251 MG: 12.0;WM-115: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060775 Approved NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA060775: AB_2684358" "unprognostic (1.97e-1)" "unprognostic (3.43e-3)" "unprognostic (2.47e-2)" "unprognostic (1.00e-3)" "unprognostic (4.21e-3)" "unprognostic (7.73e-3)" "unprognostic (6.50e-2)" "unprognostic (8.17e-2)" "unprognostic (3.57e-1)" "unprognostic (9.15e-2)" "unprognostic (3.83e-2)" "unprognostic (3.09e-2)" "unprognostic (5.17e-2)" "unprognostic (2.05e-5)" "unprognostic (8.61e-3)" "unprognostic (1.52e-1)" "unprognostic (2.05e-1)" 2.1 5.0 8.4 0.2 9.9 0.1 1.2 30.1 7.7 1.7 1.0 0.4 0.2 1.8 1.2 0.1 0.4 0.5 0.2 7.6 17.9 0.1 0.0 2.1 0.0 9.3 12.3 0.5 0.3 0.0 1.7 0.4 11.4 2.0 0.3 9.9 4.1 1.4 1.0 0.6 0.3 1.0 9.5 0.0 0.4 0.6 10.8 0.0 0.0 0.0 0.0 0.7 0.2 11.4 0.0 5.2 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 5.5 0.0 0.0 0.1 2.8 0.0 5.0 1.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.6 0.0 0.1 0.1 0.5 1.0 0.0 0.0 0.2 7.3 0.2 6.9 0.0 0.3 1.0 0.0 0.0 7.5 43.8 0.1 0.1 0.0 0.7 0.0 0.1 0.0 0.1 1.9 0.1 12.0 0.6 0.1 0.0 7.2 0.0 33.5 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 8.4 9.9 30.1 7.7 7.6 17.9 9.3 12.3 11.4 9.5 10.8 11.4 0.2 25.6 1.1 13.1 0.0 0.1 0.0 0.0 0.0 14.4 0.2 0.3 1.0 0.0 1.3 0.0 52.1 0.1 0.0 0.1 0.0 0.0 1.9 0.4 21.5 0.7 3.5 0.0 214.6 0.2 0.0 2.8 0.0 0.3 0.0 0.1 0.0 0.0 0.1 72.3 333.1 1.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 2.8 0.0 0.9 0.0 986.7 398.2 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.6 0.0 0.2 0.5 0.8 0.6 0.0 0.1 0.0 0.2 4.2 0.9 0.0 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 NR4A2 "HZF-3, NOT, NURR1, RNR1, TINUR" ENSG00000153234 "Nuclear receptor subfamily 4 group A member 2" P43354 2 156324437-156342348 "Cancer-related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 129.3;bone marrow: 130.8;ovary: 129.2" "Cell type enhanced" "Detected in many" "B-cells: 511.7;dendritic cells: 410.4;Langerhans cells: 782.3;Macrophages: 577.5;T-cells: 465.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 6.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 16.0;HMC-1: 10.9;SK-MEL-30: 8.1;U-266/70: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000543, CAB010481" Uncertain Supported "Nuclear speckles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "CAB010481: AB_2298676, HPA000543: AB_1854631" "unprognostic (4.26e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-2)" "unprognostic (4.10e-2)" "unprognostic (3.04e-2)" "unprognostic (5.26e-2)" "unprognostic (2.30e-1)" "unprognostic (6.14e-2)" "unprognostic (8.63e-2)" "unprognostic (3.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.89e-1)" "unprognostic (2.39e-2)" "unprognostic (3.58e-2)" "unprognostic (3.43e-1)" "unprognostic (9.29e-3)" "unprognostic (1.11e-1)" 40.0 129.3 4.3 24.5 44.1 130.8 15.6 36.2 8.8 18.3 5.9 9.5 2.9 15.0 1.7 11.4 28.2 32.7 36.6 15.1 3.6 19.2 20.2 18.8 6.3 3.2 9.2 129.2 9.2 8.8 54.0 5.2 2.8 25.6 18.7 5.3 19.2 15.5 11.6 12.8 7.8 14.5 0.9 4.6 19.9 5.6 2.5 9.7 15.2 7.8 1.4 50.9 14.0 6.4 0.9 1.3 0.5 1.8 3.2 0.7 0.9 1.1 5.5 0.4 1.3 0.0 3.3 0.0 1.2 0.4 0.4 1.6 2.6 0.7 0.4 1.3 1.4 1.0 16.0 0.0 0.6 0.7 10.9 0.6 1.2 0.4 0.4 2.1 0.3 0.0 1.6 1.0 1.1 1.9 0.0 0.8 2.1 1.5 0.8 0.2 0.7 3.3 0.6 0.8 2.7 0.1 2.6 4.1 8.1 0.3 0.2 1.0 0.7 2.9 0.8 0.7 0.4 14.2 1.8 0.0 5.3 1.0 7.0 1.9 1.7 2.4 1.0 0.3 0.5 0.4 0.3 0.5 1.9 0.3 0.5 0.2 6.5 0.0 0.7 0.0 0.4 0.5 4.3 44.1 36.2 8.8 15.1 3.6 3.2 9.2 2.8 0.9 2.5 6.4 70.7 25.6 124.7 7.8 511.7 218.6 25.8 87.5 298.7 11.8 120.8 160.1 11.9 17.2 58.3 71.7 50.1 4.7 410.4 35.0 0.0 13.1 36.7 209.6 33.9 111.9 206.4 12.0 5.8 9.1 6.5 164.9 103.9 349.7 349.3 4.3 45.0 6.8 125.1 0.0 0.8 95.4 42.7 161.1 782.3 37.2 4.1 577.5 241.9 5.6 7.9 1.6 3.1 4.0 2.3 11.7 41.9 0.7 203.5 49.1 25.9 0.4 54.6 33.4 13.1 63.0 169.8 1.8 3.3 230.2 213.7 9.9 465.1 34.4 57.5 29.5 GPD2 ENSG00000115159 "Glycerol-3-phosphate dehydrogenase 2" P43304 2 156435290-156613735 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 151.1;Late spermatids: 95.5;Oligodendrocyte precursor cells: 148.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 3.3;eosinophil: 1.7;intermediate monocyte: 1.6;myeloid DC: 2.7;neutrophil: 1.1;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 1.7;monocytes: 3.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008012, HPA045506" Enhanced Supported Mitochondria "Intracellular and membrane" NA NA 620000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" Mitochondria "HPA008012: AB_1079013, HPA045506: AB_2679355" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (4.79e-3)" "unprognostic (3.25e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (1.44e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (2.60e-3)" "unprognostic (6.67e-2)" "unprognostic (6.02e-3)" "unprognostic (1.73e-1)" "unprognostic (1.89e-1)" "unprognostic (2.41e-1)" "unprognostic (1.01e-2)" 8.2 5.7 13.3 8.1 17.7 13.4 16.2 15.2 18.6 10.3 6.5 18.6 14.4 6.8 5.2 20.3 18.2 8.9 6.2 19.8 16.3 8.0 3.4 11.4 7.0 13.5 16.2 8.6 6.8 20.5 5.5 6.7 13.1 10.9 18.0 9.6 14.9 7.1 24.7 12.5 15.7 6.1 14.5 8.5 17.4 5.5 18.5 6.1 12.2 14.3 8.6 14.3 9.5 13.6 39.0 27.2 15.3 24.5 32.6 39.6 0.1 48.0 31.2 32.1 38.6 53.9 35.7 8.4 31.9 27.4 13.2 44.5 28.9 44.5 41.4 23.9 9.5 6.0 46.9 0.0 12.0 11.2 12.6 19.5 15.4 55.6 27.1 20.6 24.1 3.7 12.0 1.9 41.7 24.4 0.3 1.0 28.7 15.2 31.0 12.3 9.8 9.2 41.8 50.7 27.3 9.9 45.0 34.4 30.4 25.9 10.9 30.8 22.8 5.7 26.9 26.5 36.5 1.3 0.3 0.4 32.9 3.0 47.1 0.3 3.3 1.7 0.3 1.6 0.5 0.1 0.1 0.4 2.7 0.2 0.3 0.2 1.1 0.4 2.3 0.3 0.5 1.5 13.3 17.7 15.2 18.6 19.8 16.3 13.5 16.2 13.1 14.5 18.5 13.6 12.1 19.2 12.3 151.1 7.8 20.0 23.3 24.9 21.1 5.5 23.4 12.8 13.1 7.2 19.8 22.0 6.2 9.6 6.2 52.1 1.9 9.5 84.8 12.3 6.1 11.3 17.4 6.9 27.9 13.4 15.2 9.2 30.5 23.3 12.7 13.0 10.4 3.4 21.3 5.0 46.9 17.1 10.2 18.6 18.7 95.5 12.2 21.0 24.9 61.8 10.8 4.2 4.1 148.3 48.7 16.2 17.4 7.2 5.6 66.7 16.0 3.9 18.2 11.1 0.0 8.3 12.3 2.6 3.2 41.7 21.5 11.1 7.6 7.0 19.4 77.8 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 ERMN "ERMIN, JN, KIAA1189" ENSG00000136541 Ermin Q8TAM6 2 157318631-157327713 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 498.6;choroid plexus: 136.2" "Cell type enriched" "Detected in some" 51 "Oligodendrocytes: 290.9" "Cancer enriched" "Detected in some" 4 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HAP1: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038295, HPA038296" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "HPA038295: AB_10805353, HPA038296: AB_10796217" "unprognostic (7.89e-2)" "unprognostic (9.06e-3)" "unprognostic (2.71e-2)" "prognostic favorable (6.93e-6)" "unprognostic (1.06e-1)" "unprognostic (2.02e-2)" "unprognostic (9.14e-2)" "unprognostic (1.79e-1)" "unprognostic (4.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.07e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-3)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (9.97e-3)" "unprognostic (5.76e-2)" 0.7 0.2 212.4 2.3 342.3 18.8 0.5 312.8 386.9 0.5 136.2 0.7 0.5 0.4 0.1 0.4 0.4 0.8 0.3 208.7 266.4 0.5 0.5 2.4 3.3 408.3 313.2 0.2 0.3 0.0 0.4 0.1 391.8 0.3 0.9 0.6 1.7 0.3 0.4 0.7 3.8 0.3 266.5 4.7 1.3 0.5 300.8 1.6 0.4 0.0 3.0 0.7 0.3 498.6 0.1 0.3 0.3 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 1.3 0.0 1.9 0.0 0.3 25.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 3.5 0.4 0.2 0.7 2.3 0.2 0.1 0.5 0.0 0.4 0.5 0.0 1.0 0.4 0.5 0.0 0.1 0.0 0.3 0.6 1.2 0.0 0.2 0.1 0.3 0.6 3.4 2.5 0.6 1.7 0.9 0.9 0.5 0.3 0.3 0.4 0.2 0.2 0.1 0.1 0.1 0.1 0.3 0.3 0.3 0.6 0.5 0.2 0.3 0.2 0.1 212.4 342.3 312.8 386.9 208.7 266.4 408.3 313.2 391.8 266.5 300.8 498.6 0.1 0.0 1.3 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.3 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.8 0.2 0.0 1.2 0.9 0.1 0.0 2.2 0.0 1.9 1.1 0.0 3.1 2.0 290.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 2.7 0.0 0.0 0.0 CYTIP "B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP" ENSG00000115165 "Cytohesin 1 interacting protein" O60759 2 157414619-157488961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 105.6;lymphoid tissue: 114.3" "Cell type enhanced" "Detected in many" "B-cells: 240.4;dendritic cells: 244.3;Langerhans cells: 552.9;Macrophages: 164.0;monocytes: 490.1;NK-cells: 181.3;Plasma cells: 392.5;T-cells: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 54.6;HDLM-2: 44.3;Karpas-707: 146.4;RPMI-8226: 46.9;U-266/70: 246.5;U-266/84: 99.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA007191 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA007191: AB_1855801" "unprognostic (3.61e-3)" "unprognostic (7.96e-3)" "unprognostic (2.00e-2)" "prognostic favorable (9.12e-4)" "unprognostic (5.71e-2)" "unprognostic (1.36e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (6.12e-2)" "unprognostic (7.41e-2)" "unprognostic (1.87e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (1.84e-1)" "unprognostic (5.49e-2)" "unprognostic (5.43e-2)" "unprognostic (3.78e-2)" 9.2 2.7 1.4 70.0 1.7 105.6 7.7 1.5 3.7 5.7 4.0 12.8 27.3 3.2 2.1 6.9 3.4 11.8 4.1 1.4 1.9 5.2 12.3 26.1 91.5 3.1 1.8 1.5 3.4 0.9 1.4 4.4 2.6 3.3 14.6 0.5 14.3 3.9 1.1 2.8 23.1 7.0 2.5 42.2 41.6 2.5 2.3 53.6 4.0 2.2 114.3 20.8 3.7 3.2 0.2 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 54.6 0.1 0.6 0.0 0.1 0.0 0.0 0.1 44.3 0.0 0.3 0.0 0.0 0.0 7.8 6.4 0.0 0.0 0.2 0.0 4.0 0.0 0.2 0.0 146.4 0.7 0.0 0.0 6.3 0.3 0.8 0.1 0.0 0.1 46.9 5.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 2.0 0.2 246.5 99.8 24.1 2.4 6.8 0.0 248.9 37.6 109.9 121.8 122.5 122.5 91.5 127.9 115.7 56.1 91.6 205.5 161.0 203.6 90.2 247.9 28.1 136.5 154.8 1.4 1.7 1.5 3.7 1.4 1.9 3.1 1.8 2.6 2.5 2.3 3.2 3.2 3.2 12.2 0.0 240.4 20.9 1.0 0.0 0.6 0.0 24.4 2.5 2.1 5.7 1.3 1.8 0.0 0.7 244.3 0.6 15.6 0.3 1.4 0.3 0.4 4.5 1.8 14.9 0.1 1.9 13.6 6.4 29.0 0.8 7.0 0.0 6.8 1.7 25.2 0.0 0.1 3.7 0.0 86.1 552.9 2.0 0.0 164.0 83.6 12.2 490.1 0.0 181.3 0.0 0.0 0.3 0.3 0.0 392.5 0.7 0.4 1.1 0.0 0.1 0.0 1.5 4.5 0.0 0.6 1.2 17.8 3.0 366.6 0.0 3.8 0.5 ACVR1C "ACVRLK7, ALK7" ENSG00000123612 "Activin A receptor type 1C" Q8NER5 2 157526767-157628864 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 31.3;brain: 10.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.2;Leydig cells: 31.7;Oligodendrocytes: 55.8;Proximal enterocytes: 17.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 10.9;HDLM-2: 5.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 29.7" "HPA007982, HPA011933" Uncertain "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA007982: AB_1078134, HPA011933: AB_1844754" "unprognostic (1.03e-1)" "unprognostic (4.55e-2)" "unprognostic (9.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.92e-1)" "unprognostic (7.64e-2)" "unprognostic (1.00e-1)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (7.12e-3)" "unprognostic (3.62e-1)" "unprognostic (9.31e-6)" "unprognostic (7.28e-2)" "unprognostic (1.95e-1)" "unprognostic (9.74e-2)" "unprognostic (1.30e-1)" 31.3 2.5 3.2 0.6 6.3 0.1 6.2 1.3 3.5 0.5 0.0 4.1 4.1 0.1 0.3 0.2 0.1 0.3 0.4 6.4 10.2 0.4 2.2 0.2 0.5 1.4 1.9 3.6 1.5 0.0 2.2 0.1 1.3 0.2 3.0 0.4 0.8 0.3 0.8 0.3 3.4 0.2 0.9 0.1 2.1 0.4 6.6 0.2 0.2 0.3 0.3 0.1 0.2 3.8 1.5 0.0 0.0 0.1 10.9 0.3 0.2 0.3 0.3 0.1 0.3 1.7 0.2 0.0 0.1 0.9 0.7 0.0 0.1 0.0 0.2 5.1 0.7 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 1.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.8 0.2 0.0 0.2 0.0 0.6 0.2 0.0 0.1 0.6 1.9 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.2 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.2 6.3 1.3 3.5 6.4 10.2 1.4 1.9 1.3 0.9 6.6 3.8 0.5 0.0 1.1 14.7 1.4 0.6 0.7 0.9 1.8 0.8 0.9 0.3 1.9 0.0 0.9 0.0 0.0 0.2 0.3 14.3 0.0 0.2 1.9 0.4 4.9 0.7 7.8 0.0 26.2 0.2 0.8 0.9 2.6 0.5 0.0 0.4 1.1 5.9 0.1 0.0 11.0 9.2 2.0 0.0 1.3 2.9 31.7 0.1 3.6 3.7 4.3 1.8 0.0 3.5 55.8 0.4 7.6 9.1 2.9 1.8 17.7 1.1 0.2 0.3 0.0 0.6 0.8 0.4 2.4 0.7 1.4 0.3 2.5 0.4 13.5 0.5 ACVR1 "ACVR1A, ACVRLK2, ALK2, SKR1" ENSG00000115170 "Activin A receptor type 1" Q04771 2 157736444-157876330 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007505, HPA046514" Approved Uncertain Nucleoli,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Cytosol "HPA007505: AB_1844752, HPA046514: AB_2732526" "unprognostic (6.99e-2)" "unprognostic (3.32e-2)" "unprognostic (3.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.73e-1)" "unprognostic (6.09e-2)" "unprognostic (3.66e-3)" "unprognostic (1.08e-1)" "unprognostic (3.99e-1)" "unprognostic (3.20e-1)" "unprognostic (2.65e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" "unprognostic (3.43e-3)" "unprognostic (3.17e-1)" "unprognostic (1.76e-2)" "prognostic unfavorable (5.17e-4)" 20.8 10.4 17.3 12.9 12.7 1.8 18.8 14.0 15.4 28.1 17.4 16.5 10.9 24.4 32.7 11.3 17.0 24.2 19.7 26.3 12.8 26.4 22.7 17.5 8.8 13.7 12.9 21.2 10.0 8.5 10.9 17.6 13.7 15.1 12.6 6.3 18.8 15.3 21.5 13.9 10.5 34.5 12.6 8.3 14.7 5.2 16.3 7.5 40.5 13.3 8.2 20.9 15.5 11.8 6.1 13.1 14.4 18.5 65.0 70.6 18.9 43.4 71.3 33.7 36.1 10.1 13.4 0.2 18.2 45.6 32.3 16.9 10.5 22.5 36.8 43.0 8.7 25.7 7.2 14.4 54.7 2.0 28.5 89.5 41.4 69.8 84.2 42.8 38.7 6.7 9.5 6.7 45.2 11.1 0.4 0.4 21.4 8.7 21.7 4.1 19.6 5.7 45.4 24.5 12.4 14.9 17.0 9.7 64.5 22.2 5.3 7.0 54.0 50.9 16.8 25.3 17.1 4.7 3.5 0.3 52.2 1.6 58.1 2.9 1.7 0.1 0.5 1.0 0.7 0.8 4.9 1.3 1.3 0.2 1.6 0.7 0.2 1.2 1.4 1.4 6.6 1.1 17.3 12.7 14.0 15.4 26.3 12.8 13.7 12.9 13.7 12.6 16.3 11.8 9.6 9.6 9.0 22.9 1.8 9.8 7.7 12.6 12.5 10.4 8.0 9.8 12.7 11.5 12.4 7.3 0.0 8.4 1.1 4.8 5.9 9.9 1.0 5.9 12.9 17.3 4.2 1.7 34.0 17.8 5.3 20.3 8.2 6.5 5.1 4.2 18.2 13.3 7.0 3.3 34.2 4.5 24.4 13.0 8.7 2.0 20.2 7.6 3.6 106.8 5.5 6.6 2.1 42.3 22.9 17.2 4.1 15.8 6.4 13.0 3.7 15.5 13.6 2.1 13.1 16.3 19.3 0.4 2.7 4.0 7.5 10.5 4.3 3.5 4.3 8.8 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 45.8;liver: 23.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Distal tubular cells: 13.7;Excitatory neurons: 32.5;Inhibitory neurons: 20.8;Oligodendrocyte precursor cells: 27.6;Proximal tubular cells: 82.1" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 0.0 0.1 3.3 0.0 2.9 0.0 0.0 1.8 3.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 3.7 1.9 45.8 23.9 0.0 0.1 1.3 1.3 0.3 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.9 1.8 3.0 3.7 1.9 1.3 1.3 1.1 1.4 1.6 2.4 0.0 0.0 0.0 24.2 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 0.0 20.8 0.0 0.0 0.9 0.0 0.1 0.3 0.5 0.0 2.8 0.0 0.1 0.0 27.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 82.1 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 CCDC148 MGC125588 ENSG00000153237 "Coiled-coil domain containing 148" Q8NFR7 2 158171073-158456753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.0;testis: 3.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 56.3;Early spermatids: 39.4;Excitatory neurons: 33.6;Inhibitory neurons: 53.0;Oligodendrocytes: 38.6;Respiratory ciliated cells: 34.1;Rod photoreceptor cells: 30.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 2.7;HBF TERT88: 1.8;RPTEC TERT1: 1.9;SCLC-21H: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042626 Uncertain Uncertain "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 41: Basophils - Cellular respiration" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA042626: AB_10806244" "unprognostic (1.88e-1)" "unprognostic (5.90e-2)" "unprognostic (3.31e-2)" "unprognostic (1.94e-4)" "unprognostic (3.29e-1)" "unprognostic (7.65e-2)" "unprognostic (1.23e-1)" "unprognostic (1.32e-1)" "unprognostic (1.09e-1)" "unprognostic (7.98e-2)" "unprognostic (1.84e-1)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (5.77e-2)" "unprognostic (3.35e-2)" "prognostic favorable (2.54e-4)" "unprognostic (6.57e-3)" 0.2 0.3 0.5 0.0 0.6 0.0 1.0 0.9 0.4 0.7 3.0 0.0 0.0 0.4 1.2 0.1 1.8 0.3 0.1 0.5 0.4 2.4 0.1 0.4 0.0 0.9 0.7 0.7 0.2 2.5 1.0 0.0 0.6 0.3 0.0 2.0 0.6 0.4 0.0 0.2 0.0 0.1 0.5 0.0 0.1 3.4 0.5 0.0 1.0 0.0 0.0 0.1 0.2 0.3 0.7 0.0 0.4 0.7 0.0 0.0 0.0 0.5 0.0 0.5 1.1 0.5 2.7 0.0 0.1 0.4 0.2 0.2 0.0 0.1 1.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.9 0.2 2.0 0.1 0.3 0.2 0.2 0.6 1.2 0.1 0.0 0.2 0.4 0.1 0.1 0.3 0.6 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.9 0.4 0.5 0.4 0.9 0.7 0.6 0.5 0.5 0.3 1.1 0.0 1.5 13.4 0.2 0.0 2.6 4.2 1.2 10.9 3.8 4.6 3.0 0.0 3.0 7.3 56.3 0.0 0.0 0.0 13.7 5.5 39.4 15.2 0.6 1.5 0.0 0.0 33.6 2.0 0.0 0.6 0.0 2.8 0.0 1.3 1.1 1.3 0.1 5.0 53.0 0.0 10.2 0.3 0.0 7.7 0.9 1.0 0.0 5.6 0.8 6.0 0.0 19.6 38.6 2.6 0.0 1.9 0.0 1.2 0.0 6.4 34.1 30.8 6.6 1.6 0.7 22.6 4.0 0.6 0.4 0.0 0.2 1.3 0.1 1.7 PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 261.0;Inhibitory neurons: 260.9;Oligodendrocyte precursor cells: 235.3;Oligodendrocytes: 864.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: AB_2685696, HPA070648: AB_2686291" "unprognostic (2.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.48e-2)" "prognostic favorable (5.80e-4)" "unprognostic (2.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (9.53e-2)" "unprognostic (1.82e-2)" "unprognostic (9.69e-2)" "prognostic favorable (3.29e-7)" "unprognostic (2.23e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-3)" 13.4 6.5 165.2 6.7 229.0 8.3 26.2 186.6 212.7 31.9 89.3 12.6 12.4 14.0 14.2 17.8 19.6 15.3 22.1 130.2 179.5 57.0 16.8 12.6 6.0 256.9 217.1 13.3 15.1 18.1 9.6 6.2 213.7 12.9 13.4 18.5 34.0 20.9 8.2 16.1 11.3 14.3 222.9 6.1 13.8 10.3 194.1 16.1 30.4 9.8 10.1 16.5 12.4 239.5 36.9 21.8 26.7 30.4 12.1 13.4 25.7 29.1 15.9 44.5 38.4 72.4 32.5 23.4 21.5 35.4 16.0 29.0 35.2 29.8 74.1 35.4 19.2 21.2 23.5 56.3 20.9 34.4 4.6 5.7 28.1 30.0 46.3 26.7 23.0 28.9 30.1 33.3 34.7 42.6 15.2 14.3 28.8 51.4 15.9 20.6 40.2 19.3 64.6 26.6 46.2 8.2 20.3 30.4 24.5 24.9 34.7 31.3 10.6 25.9 29.2 19.3 38.2 19.8 18.0 17.0 14.8 19.2 25.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.2 0.1 0.0 0.4 0.1 0.4 0.0 2.0 0.2 0.7 0.2 165.2 229.0 186.6 212.7 130.2 179.5 256.9 217.1 213.7 222.9 194.1 239.5 59.8 41.7 18.9 28.7 3.1 27.0 21.3 23.5 34.1 44.5 44.3 35.9 49.7 38.6 28.7 47.8 29.2 0.2 3.5 17.7 23.5 21.3 14.6 21.0 12.2 71.1 9.0 24.6 261.0 18.1 0.3 15.3 26.0 38.5 10.1 11.8 23.2 28.6 3.1 5.0 260.9 16.6 16.2 7.6 10.0 9.2 10.8 6.2 7.2 163.9 4.5 8.6 2.1 235.3 864.7 17.4 16.7 17.0 5.2 44.6 12.4 33.1 29.0 19.2 13.1 11.4 13.9 15.4 6.3 30.4 30.4 0.3 5.0 15.5 19.4 26.8 DAPL1 ENSG00000163331 "Death associated protein like 1" A0PJW8 2 158795317-158862781 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 196.9;esophagus: 242.0;skin 1: 301.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 212.9;Muller glia cells: 913.0;Squamous epithelial cells: 736.5" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HaCaT: 4.0;hTCEpi: 23.2;SCLC-21H: 5.9;U-87 MG: 8.4" "HPA046937, HPA058635" Enhanced Approved "Nucleoplasm,Nuclear bodies,Microtubules" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Nuclear bodies, Microtubules" "HPA046937: AB_2679870, HPA058635: AB_2732625" "unprognostic (3.95e-5)" "prognostic favorable (8.43e-4)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.98e-1)" "unprognostic (4.63e-2)" "unprognostic (8.59e-2)" "unprognostic (5.24e-2)" "unprognostic (4.59e-2)" "unprognostic (2.44e-1)" "unprognostic (1.41e-1)" "unprognostic (2.44e-3)" "unprognostic (4.09e-2)" "unprognostic (6.68e-2)" "unprognostic (3.00e-2)" "unprognostic (2.30e-3)" 1.9 56.0 1.6 0.1 1.8 0.8 28.7 1.6 6.6 47.6 1.2 2.9 0.5 0.6 196.9 242.0 80.5 0.6 0.5 1.3 9.3 3.6 0.2 1.6 0.6 1.5 5.3 1.0 22.8 0.0 24.4 0.1 2.4 9.2 0.7 115.6 30.2 1.1 1.0 301.0 1.0 0.5 1.3 0.3 1.5 1.5 4.3 4.8 34.3 0.0 25.0 8.6 108.1 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.1 2.3 0.0 0.0 0.0 0.1 0.2 23.2 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.4 5.9 0.0 0.0 0.0 0.6 0.0 0.7 1.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.0 1.2 0.8 0.5 0.1 0.6 0.2 0.4 0.2 0.1 0.3 0.4 0.1 0.1 0.5 0.7 0.1 1.2 0.4 0.1 1.6 1.8 1.6 6.6 1.3 9.3 1.5 5.3 2.4 1.3 4.3 1.2 0.6 0.0 0.0 0.0 4.1 106.9 51.8 74.8 212.9 7.2 15.0 19.6 0.1 2.8 29.8 9.2 6.2 6.0 4.9 2.0 3.9 7.6 13.8 5.6 2.2 2.0 3.0 0.0 0.2 6.0 12.8 2.4 0.0 5.4 4.5 148.1 0.7 14.3 14.7 3.3 0.4 2.0 14.2 9.1 9.3 56.1 4.1 5.0 12.4 0.0 5.4 913.0 2.1 1.0 0.1 5.8 7.1 2.2 3.4 11.8 5.9 13.3 4.8 23.8 0.0 1.9 10.9 10.8 4.2 736.5 126.6 4.5 3.1 1.7 2.3 67.4 TANC1 "KIAA1728, ROLSB" ENSG00000115183 "Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1" Q9C0D5 2 158968640-159232659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 212.0;Microglial cells: 159.3;Oligodendrocyte precursor cells: 193.5;Oligodendrocytes: 223.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036750 Approved NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "HPA036750: AB_10670241" "unprognostic (2.93e-1)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.91e-2)" "unprognostic (2.43e-2)" "unprognostic (3.96e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.43e-2)" "unprognostic (3.94e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (7.43e-2)" "unprognostic (3.07e-2)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (1.12e-1)" 9.1 5.9 9.7 3.9 14.0 0.2 7.8 15.8 7.5 10.2 8.1 9.2 6.4 10.9 2.0 12.7 5.8 7.5 22.1 13.0 15.8 6.6 4.4 12.6 3.3 18.4 13.6 6.3 5.9 5.9 3.5 13.4 18.1 7.8 7.0 12.0 7.1 4.4 2.7 20.5 6.5 12.9 11.9 5.0 5.9 1.9 21.1 3.6 10.8 4.3 4.8 8.6 6.8 20.0 8.7 7.4 18.4 14.3 16.7 7.1 9.0 6.6 13.9 6.6 10.4 8.0 9.5 0.0 22.6 21.2 5.0 18.7 5.9 26.1 8.4 0.0 13.7 5.6 11.8 1.5 19.7 0.7 14.3 11.0 21.3 12.4 23.1 30.1 35.8 8.5 1.4 39.8 11.1 3.9 5.5 0.0 2.4 9.8 6.7 0.7 10.0 12.9 15.2 34.9 2.8 18.9 14.5 6.6 34.9 11.4 7.2 5.6 33.8 14.7 8.6 3.1 6.1 19.7 14.5 0.0 8.2 0.0 40.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 14.0 15.8 7.5 13.0 15.8 18.4 13.6 18.1 11.9 21.1 20.0 42.1 28.9 17.1 34.9 0.2 48.9 13.5 21.7 46.7 30.1 19.3 16.9 64.7 15.7 23.5 11.0 6.2 2.9 0.9 18.9 3.9 13.3 1.1 11.1 12.1 48.3 0.0 4.2 9.9 12.5 3.8 16.0 33.1 11.7 17.2 47.6 35.3 8.7 2.0 212.0 54.7 16.6 10.2 2.8 10.3 1.7 10.5 1.7 24.9 159.3 0.6 48.6 1.0 193.5 223.7 13.4 22.7 4.9 1.6 14.4 10.5 4.9 12.5 4.9 13.1 11.6 27.5 0.5 2.1 38.6 42.1 2.1 2.5 14.6 14.9 17.3 WDSUB1 "FLJ36175, UBOX6, WDSAM1" ENSG00000196151 "WD repeat, sterile alpha motif and U-box domain containing 1" Q8N9V3 2 159235798-159286703 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036840, HPA058172" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli "Nucleoplasm, Cytosol" "HPA036840: AB_10670926, HPA058172: AB_2683628" "unprognostic (1.37e-2)" "prognostic favorable (3.35e-4)" "unprognostic (2.56e-1)" "unprognostic (7.33e-3)" "unprognostic (3.44e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.76e-3)" "unprognostic (4.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (6.75e-2)" "unprognostic (3.46e-3)" "unprognostic (8.49e-2)" "unprognostic (1.72e-1)" "unprognostic (1.00e-2)" "unprognostic (2.87e-2)" 6.7 10.9 9.1 4.6 10.2 10.6 12.0 10.7 12.0 7.8 11.7 6.7 4.9 8.2 17.5 7.5 9.8 5.9 10.1 8.9 9.3 23.5 6.9 9.0 7.9 9.7 9.3 13.5 10.6 13.9 9.1 9.7 9.8 9.1 7.6 11.1 10.4 6.8 6.7 6.9 5.8 6.6 8.9 8.6 7.4 6.7 9.4 7.0 17.3 6.5 5.8 6.2 6.3 11.7 8.4 6.3 5.4 9.0 10.1 11.4 19.1 6.7 13.0 11.4 20.4 13.7 13.6 11.7 6.9 9.9 20.3 5.2 15.9 5.9 16.1 4.5 13.4 12.1 6.8 14.0 12.2 10.2 15.6 6.7 21.5 14.4 12.0 22.2 9.8 14.9 16.0 8.5 11.1 8.8 7.3 18.5 7.5 14.3 13.6 11.3 8.3 6.2 13.6 12.2 10.3 6.8 7.0 8.6 15.9 26.0 6.7 17.3 4.1 8.2 6.2 11.8 6.5 4.2 7.7 10.7 14.4 12.6 5.3 3.9 11.1 3.5 14.3 8.6 10.9 11.8 5.6 9.1 12.2 9.9 6.7 8.0 0.8 20.8 7.9 11.6 3.3 7.8 9.1 10.2 10.7 12.0 8.9 9.3 9.7 9.3 9.8 8.9 9.4 11.7 8.2 12.8 6.8 28.4 10.7 5.4 8.7 13.0 11.4 6.9 9.3 8.0 11.3 10.0 11.3 20.2 2.1 25.4 11.2 5.1 35.2 9.5 4.5 13.7 6.9 7.0 5.4 6.7 42.4 3.6 9.2 9.9 10.2 16.1 12.0 13.2 6.4 2.0 17.3 5.0 52.0 4.5 12.2 14.8 4.8 2.9 12.8 10.2 5.4 29.0 9.2 6.6 14.4 31.7 34.6 4.0 7.0 11.3 3.8 6.8 6.9 23.7 15.0 9.7 0.0 12.0 7.8 10.1 22.5 11.1 6.3 23.0 9.1 12.7 7.1 7.3 BAZ2B WALp4 ENSG00000123636 "Bromodomain adjacent to zinc finger domain 2B" Q9UIF8 2 159318979-159616569 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 477.3;Oligodendrocytes: 604.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 115.8;neutrophil: 213.2" "Lineage enriched" "Detected in all" 8 "granulocytes: 213.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019819, HPA059292" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Cytosol "HPA019819: AB_1845282, HPA059292: AB_2683968" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (5.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-2)" "unprognostic (4.94e-3)" "unprognostic (1.19e-1)" "unprognostic (5.64e-2)" "unprognostic (5.49e-3)" "unprognostic (9.01e-2)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (2.14e-1)" "unprognostic (3.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.14e-2)" 20.6 23.8 23.0 18.1 43.7 36.7 22.1 57.4 26.8 23.8 3.6 18.2 17.1 33.6 19.7 22.1 24.4 26.1 18.4 21.8 41.4 17.3 16.8 24.7 14.7 45.3 29.1 42.4 19.3 24.6 17.5 20.5 47.7 18.4 16.4 52.0 23.4 19.8 18.4 17.5 18.5 23.5 26.0 20.9 17.0 26.4 43.7 21.5 25.4 22.3 13.6 20.9 14.7 75.3 7.4 14.7 48.4 29.4 14.2 22.8 8.4 15.3 18.7 8.2 9.6 22.1 19.9 12.4 25.8 15.0 8.4 16.6 19.4 20.7 13.0 4.5 11.1 24.7 26.9 3.1 9.3 16.3 17.0 18.0 22.2 20.6 22.2 30.4 42.5 8.3 25.7 2.3 13.1 9.1 5.6 10.5 16.1 1.5 12.4 13.1 15.7 8.8 16.4 26.2 32.1 27.9 30.3 3.7 18.5 25.0 5.8 46.7 42.6 14.9 30.1 6.5 10.3 9.0 1.0 14.0 14.1 17.5 10.0 115.8 27.4 36.4 10.1 12.0 8.3 6.5 6.1 10.5 17.7 9.6 4.1 6.6 213.2 19.7 11.3 24.5 7.1 6.0 23.0 43.7 57.4 26.8 21.8 41.4 45.3 29.1 47.7 26.0 43.7 75.3 105.3 99.3 148.0 477.3 34.3 32.6 70.1 35.8 66.0 91.8 56.4 38.9 60.8 61.5 71.5 68.0 310.6 18.5 40.1 45.4 9.8 55.5 158.0 69.8 63.9 82.5 99.9 42.1 180.4 38.9 7.2 54.9 59.7 118.9 73.9 71.9 71.0 29.4 25.5 94.2 177.3 52.1 36.7 58.0 37.1 35.4 59.4 76.6 14.2 289.5 81.4 87.3 41.2 300.6 604.3 54.3 55.5 35.0 42.2 50.0 51.7 12.4 73.3 332.3 13.1 74.9 54.1 98.2 20.7 49.6 37.5 26.7 38.9 83.2 48.6 91.6 MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 33.3;Cardiomyocytes: 88.4;Cytotrophoblasts: 36.2;dendritic cells: 28.2;Extravillous trophoblasts: 38.8;Hofbauer cells: 34.0;Syncytiotrophoblasts: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 38.3 30.0 16.4 37.9 21.7 43.2 48.2 32.3 21.5 38.6 25.1 33.2 30.0 45.0 34.2 67.3 37.5 38.1 48.9 15.8 16.1 32.8 40.1 38.2 47.9 17.4 17.1 47.5 22.3 36.6 22.7 46.9 17.7 38.1 36.9 37.9 26.9 36.3 55.2 38.6 30.0 50.6 14.9 45.1 33.5 62.0 17.1 60.8 47.5 44.1 52.2 39.0 37.5 21.8 50.3 35.3 88.7 40.7 61.9 81.9 89.1 83.9 81.1 82.5 73.9 70.9 57.5 71.0 36.8 84.2 46.8 61.3 55.4 74.5 102.9 75.9 43.2 96.0 53.8 53.3 60.7 79.9 72.6 72.7 83.0 99.5 86.5 92.5 99.3 50.7 75.6 65.6 82.9 44.2 52.4 73.8 84.6 54.6 47.3 75.0 64.5 59.3 74.6 112.1 51.9 48.6 65.6 48.2 67.0 94.3 56.9 94.4 93.5 86.9 51.9 53.9 47.2 51.5 61.0 96.8 54.1 46.8 84.0 83.5 28.8 59.6 28.6 29.5 33.3 27.6 30.4 32.4 27.6 26.4 36.3 35.9 127.5 39.4 43.4 22.3 34.3 30.9 16.4 21.7 32.3 21.5 15.8 16.1 17.4 17.1 17.7 14.9 17.1 21.8 33.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 36.2 28.2 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 38.8 13.5 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 44.2 5.8 0.0 0.0 0.0 CD302 "BIMLEC, CLEC13A, DCL-1, KIAA0022" ENSG00000241399 "CD302 molecule" Q8IX05 2 159768628-159798255 "CD markers, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 193.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 352.2;Kupffer cells: 382.4;Macrophages: 194.3;monocytes: 166.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 215 "dendritic cells: 24.4;granulocytes: 32.2;monocytes: 33.0" "Cell line enriched" "Detected in many" 5 "ASC diff: 246.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 110000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (2.52e-1)" "unprognostic (5.44e-2)" "unprognostic (1.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.03e-1)" "unprognostic (6.88e-2)" "unprognostic (1.68e-2)" "unprognostic (9.12e-3)" "unprognostic (5.29e-3)" "unprognostic (2.37e-2)" "unprognostic (4.38e-2)" "unprognostic (2.14e-1)" "unprognostic (4.67e-3)" "unprognostic (1.75e-2)" "unprognostic (6.61e-2)" "unprognostic (7.45e-2)" "unprognostic (3.61e-3)" 49.4 25.5 6.5 15.5 6.6 30.6 31.0 7.1 9.2 34.6 10.6 16.8 24.1 21.8 14.2 11.7 15.0 30.7 13.3 6.1 7.5 16.9 193.8 50.0 11.7 8.8 7.2 41.9 17.6 10.9 3.2 19.4 8.5 21.3 20.7 2.1 12.0 20.4 2.9 6.2 28.1 22.5 7.5 31.3 15.7 9.0 6.6 9.7 31.1 17.3 9.9 24.6 13.3 8.5 0.1 1.4 1.2 0.0 246.9 51.5 0.0 5.3 25.9 7.4 10.9 1.6 2.2 0.4 2.0 13.5 7.8 0.0 5.5 3.0 10.1 1.6 8.6 7.0 1.3 3.6 12.3 18.6 6.0 41.2 1.4 8.0 0.0 6.0 18.9 0.0 0.6 5.8 9.5 0.6 0.0 13.1 2.4 0.0 6.7 0.0 1.8 0.2 1.6 0.2 2.7 2.9 1.8 5.9 5.7 3.8 4.8 18.3 4.1 13.7 0.0 0.2 4.1 0.5 0.0 0.0 9.9 1.5 3.1 13.5 33.0 32.2 0.0 24.1 0.0 0.1 0.0 0.0 24.4 0.1 0.0 0.0 29.2 0.1 26.1 6.8 0.0 12.5 6.5 6.6 7.1 9.2 6.1 7.5 8.8 7.2 8.5 7.5 6.6 8.5 28.0 44.8 111.9 0.0 5.0 6.6 15.9 2.4 16.5 3.3 20.2 15.2 3.9 31.5 26.5 3.7 0.0 2.5 19.3 3.7 0.0 4.0 31.7 3.0 38.7 25.3 9.6 21.0 0.0 3.5 10.5 80.5 20.4 3.0 30.9 26.7 65.7 352.2 42.7 3.3 0.0 25.2 0.0 382.4 97.3 16.4 122.7 194.3 19.6 0.0 166.6 2.1 2.1 0.0 0.0 2.3 12.2 93.6 3.5 13.9 19.6 4.1 17.1 2.4 65.7 24.8 30.7 27.9 11.6 3.6 4.4 2.7 6.5 8.6 22.7 10.4 LY75-CD302 ENSG00000248672 "LY75-CD302 readthrough" 2 159771851-159904710 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.4;intestine: 1.8;lymphoid tissue: 2.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 1.1;Club cells: 1.3;granulocytes: 1.3;Microglial cells: 1.0;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 7.0;HDLM-2: 7.4;Karpas-707: 27.6;RT4: 11.7;TIME: 7.3" HPA049108 Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA049108: AB_2680635" "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (2.33e-1)" "unprognostic (1.86e-1)" "unprognostic (9.04e-2)" "unprognostic (1.68e-4)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (3.32e-1)" "unprognostic (4.47e-2)" "unprognostic (1.88e-1)" 0.1 0.0 0.1 2.3 0.0 2.4 0.7 0.2 0.1 0.3 0.0 1.2 1.8 0.2 0.0 0.0 0.4 0.4 0.2 0.0 0.2 0.2 0.1 1.2 0.7 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 1.4 0.1 0.2 0.6 0.3 0.1 0.2 1.9 0.6 0.0 0.4 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 7.0 3.5 1.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 7.4 0.0 4.3 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.0 3.3 0.0 0.0 27.6 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.1 0.0 11.7 0.0 0.0 3.2 0.7 0.0 0.1 0.0 1.2 7.3 0.0 0.0 0.0 0.0 2.4 0.5 0.8 0.0 1.7 0.0 2.5 2.9 3.4 1.1 3.1 1.6 0.9 1.0 1.3 7.3 1.0 1.1 0.9 5.5 0.6 1.4 1.6 1.3 2.4 0.1 0.0 0.2 0.1 0.0 0.2 0.5 0.1 0.3 0.2 0.2 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LY75 "CD205, CLEC13B, DEC-205" ENSG00000054219 "Lymphocyte antigen 75" O60449 2 159803355-159904756 "CD markers, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 78.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 27.8;monocytes: 96.5;Proximal enterocytes: 33.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 21.8;HDLM-2: 21.7;Karpas-707: 85.3;RT4: 30.1;THP-1: 22.3" "CAB001450, HPA049108, HPA054073" Enhanced Approved "Golgi apparatus" NA NA 1300000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus" "CAB001450: AB_563525, HPA049108: AB_2680635, HPA054073: AB_2682370" "unprognostic (7.29e-3)" "unprognostic (1.92e-3)" "unprognostic (3.15e-1)" "unprognostic (1.52e-2)" "unprognostic (4.60e-3)" "unprognostic (3.65e-2)" "unprognostic (8.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.80e-1)" "unprognostic (2.36e-1)" "unprognostic (8.74e-3)" "unprognostic (3.92e-1)" "prognostic unfavorable (2.39e-5)" "unprognostic (2.66e-1)" "unprognostic (4.89e-2)" "unprognostic (1.94e-2)" "prognostic favorable (3.86e-4)" 2.0 1.9 1.1 18.7 1.0 9.6 9.4 1.1 1.2 7.3 0.7 12.4 18.0 2.6 0.7 5.0 8.5 7.7 1.0 0.9 1.3 3.7 2.0 7.7 30.3 1.7 1.1 1.0 1.4 1.1 0.6 1.3 1.6 1.8 11.9 0.7 7.8 2.6 0.3 7.4 17.6 2.3 1.8 18.4 7.1 0.4 1.2 78.4 17.3 0.9 22.1 10.3 2.2 1.8 3.5 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 9.1 21.8 15.7 0.7 0.0 0.0 0.4 0.0 0.1 0.0 21.7 0.0 4.4 0.2 0.1 0.4 3.3 0.1 0.3 0.1 0.6 0.2 0.0 11.1 0.0 0.0 85.3 0.0 0.0 0.0 5.8 0.5 0.5 0.0 6.0 0.0 3.8 6.4 30.1 0.0 0.0 7.0 5.0 0.0 0.2 0.0 22.3 16.7 0.0 0.0 0.0 0.0 13.2 2.4 3.0 0.0 7.7 0.0 2.6 1.2 2.4 4.2 1.7 4.6 3.7 3.8 4.8 2.9 2.7 4.3 5.1 3.7 5.2 0.7 1.0 3.0 1.4 1.1 1.0 1.1 1.2 0.9 1.3 1.7 1.1 1.6 1.8 1.2 1.8 1.7 0.0 3.4 0.0 15.4 7.5 2.2 5.6 7.4 0.2 9.9 12.1 0.5 4.3 6.3 23.9 2.1 0.1 10.6 27.8 0.0 0.8 0.6 15.4 1.3 3.3 1.8 6.9 0.0 5.5 0.1 1.8 8.6 9.4 11.4 1.7 2.2 0.2 3.9 0.0 0.0 9.8 4.1 10.1 11.3 0.3 2.5 11.5 5.4 0.0 96.5 0.2 13.4 0.0 0.0 4.9 10.9 0.4 8.1 1.3 33.5 2.0 20.7 0.2 0.0 3.7 1.3 0.0 0.7 4.5 6.7 0.3 14.2 0.9 12.3 5.6 PLA2R1 "CLEC13C, PLA2-R, PLA2G1R, PLA2IR" ENSG00000153246 "Phospholipase A2 receptor 1" Q13018 2 159932006-160062615 "Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 39.1;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Excitatory neurons: 34.6;Inhibitory neurons: 43.5;Muller glia cells: 33.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 14.5;ASC TERT1: 19.5;BJ hTERT+: 16.2;hTERT-RPE1: 26.3;TIME: 47.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB068217, CAB068218" Approved Approved Cytosol "Secreted to blood" NA NA 960000 "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "CAB068217: AB_2665660, CAB068218: AB_2665661" "unprognostic (2.04e-1)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.39e-2)" "unprognostic (4.91e-3)" "unprognostic (6.01e-2)" "unprognostic (9.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-2)" "unprognostic (9.38e-3)" "unprognostic (4.30e-3)" "unprognostic (2.82e-1)" "unprognostic (2.14e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (2.62e-1)" "unprognostic (6.58e-2)" "unprognostic (2.02e-1)" 4.7 2.9 0.7 1.4 0.8 0.0 14.9 9.7 2.2 6.9 1.7 3.1 3.9 8.8 2.9 4.7 5.4 9.3 2.5 0.5 1.5 20.8 1.4 2.6 1.9 2.0 2.7 10.8 0.6 19.7 2.2 3.8 2.1 3.1 3.2 5.6 39.1 2.9 0.5 10.9 6.1 6.9 1.4 5.1 1.6 1.0 2.5 0.6 41.9 1.3 2.7 3.9 6.0 1.0 0.2 1.6 0.6 0.0 14.5 19.5 0.1 6.8 16.2 1.3 1.8 0.0 3.4 0.0 0.4 7.2 1.4 3.3 0.1 5.0 1.4 0.0 0.0 0.0 11.8 0.0 1.2 0.0 0.0 7.9 5.4 1.9 2.1 26.3 9.3 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 1.4 0.7 0.0 0.0 11.8 2.2 0.0 1.7 2.6 0.2 47.3 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.7 0.8 9.7 2.2 0.5 1.5 2.0 2.7 2.1 1.4 2.5 1.0 11.1 6.4 2.8 20.9 0.1 9.4 2.7 18.1 21.6 2.7 22.1 14.5 4.1 5.7 11.3 33.1 0.0 7.3 0.5 1.7 0.0 0.6 0.1 5.6 22.0 4.0 1.2 0.0 34.6 2.0 1.3 14.8 0.0 9.4 1.3 9.6 8.6 0.0 0.6 16.8 43.5 7.2 4.1 0.0 2.1 1.4 16.1 0.5 7.2 25.3 0.0 33.5 0.0 5.5 1.8 5.1 11.3 16.6 0.1 2.6 15.6 2.3 8.1 1.4 6.6 3.4 4.8 0.1 1.0 9.3 5.4 1.5 0.6 6.3 7.5 3.0 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 RBMS1 "C2orf12, DKFZp564H0764, HCC-4, MSSP-1, MSSP-2, MSSP-3, SCR2, YC1" ENSG00000153250 "RNA binding motif single stranded interacting protein 1" P29558 2 160272151-160493807 "Predicted intracellular proteins" "DNA replication" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 398.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047943, HPA061791" Enhanced Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "HPA047943: AB_2797235, HPA061791: AB_2684611" "unprognostic (2.81e-1)" "unprognostic (2.44e-2)" "unprognostic (3.78e-2)" "unprognostic (1.38e-3)" "unprognostic (2.50e-1)" "unprognostic (6.81e-3)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.14e-1)" "unprognostic (7.16e-3)" "unprognostic (6.70e-2)" "prognostic unfavorable (1.33e-7)" "unprognostic (1.84e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (2.32e-1)" 58.2 22.6 8.7 43.3 13.3 35.8 34.5 9.7 11.9 36.6 17.2 38.9 12.8 51.7 12.6 28.9 31.6 34.1 41.0 7.2 10.7 36.5 22.3 47.7 28.3 13.8 12.3 44.1 10.2 50.4 16.0 83.8 15.0 24.0 15.8 6.8 19.2 28.6 16.4 29.4 20.5 56.9 10.9 40.7 20.1 10.4 13.4 26.1 23.0 23.8 22.0 57.0 31.6 10.2 50.5 18.2 63.9 8.4 90.2 155.6 77.1 62.7 89.1 42.4 43.8 50.9 36.9 0.4 76.3 106.6 20.0 30.0 31.1 46.0 69.2 40.9 23.2 18.9 44.2 41.0 82.3 30.8 1.1 187.9 35.6 73.7 32.8 56.7 67.5 15.1 1.2 23.0 103.2 39.4 28.8 31.2 39.3 8.3 40.1 21.6 55.7 25.5 64.9 61.1 8.3 21.7 39.1 22.9 60.2 78.8 11.7 47.9 81.7 75.3 47.7 69.7 57.5 12.2 0.7 21.2 60.7 46.2 49.2 4.0 20.5 26.2 8.6 12.0 29.5 0.9 14.9 13.3 13.7 1.9 24.1 10.9 44.4 13.7 6.9 7.6 2.7 11.0 8.7 13.3 9.7 11.9 7.2 10.7 13.8 12.3 15.0 10.9 13.4 10.2 102.8 112.2 97.8 12.1 37.3 91.1 110.0 59.1 55.2 3.0 44.7 43.2 62.3 18.6 48.1 69.9 0.0 99.1 83.9 0.4 25.4 24.5 59.2 39.8 141.4 126.0 0.0 38.3 132.7 47.3 112.6 161.8 36.7 42.0 20.3 40.8 162.8 29.1 126.3 1.7 136.1 0.5 22.4 123.4 80.2 15.5 88.9 103.8 55.2 153.6 81.2 20.8 93.7 116.1 19.7 96.4 1.3 98.9 23.3 107.0 0.3 36.4 54.1 1.4 78.9 113.6 185.9 6.7 14.5 47.3 82.5 398.3 113.0 53.4 0.5 175.5 TANK "I-TRAF, TRAF2" ENSG00000136560 "TRAF family member associated NFKB activator" Q92844 2 161136908-161236230 "Predicted intracellular proteins" "DNA damage, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010345, HPA037675, HPA037676" Approved Supported Nucleoli,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" Cytosol Nucleoli "CAB010345: AB_2199871, HPA037675: AB_2675600, HPA037676: AB_2675601" "unprognostic (1.14e-2)" "unprognostic (9.68e-2)" "unprognostic (1.53e-1)" "unprognostic (5.27e-2)" "unprognostic (3.98e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.71e-1)" "unprognostic (2.98e-2)" "unprognostic (4.16e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-1)" "prognostic unfavorable (2.78e-6)" "unprognostic (2.13e-2)" "unprognostic (2.00e-1)" "unprognostic (5.69e-3)" "unprognostic (2.30e-2)" 42.9 36.2 20.9 46.2 23.6 84.2 57.7 22.1 24.7 30.5 25.3 32.4 28.0 30.7 27.0 29.8 35.0 43.0 27.1 20.1 24.1 29.1 66.5 39.7 52.8 24.0 25.5 30.8 22.9 27.8 19.7 36.9 23.5 24.6 35.8 32.1 26.6 24.7 52.3 26.7 29.1 32.5 21.4 43.2 30.2 22.3 21.9 42.1 36.4 43.3 51.4 49.0 25.0 25.1 39.2 24.5 31.7 36.3 91.3 124.9 45.2 58.0 86.4 39.3 57.7 30.8 50.5 53.1 38.7 67.6 28.2 27.5 19.2 43.4 59.5 126.6 20.5 29.8 22.5 79.1 72.4 51.1 32.2 98.3 66.6 59.6 46.6 73.5 101.7 32.0 30.5 68.7 77.7 29.3 31.4 50.7 18.2 40.9 21.5 17.9 45.5 35.2 86.3 62.1 26.4 30.7 37.4 40.6 60.4 43.2 17.5 64.9 108.2 50.4 29.3 25.7 34.0 46.6 46.1 80.9 66.9 40.3 40.8 122.2 71.4 97.1 36.0 78.5 55.9 63.8 58.8 53.1 66.5 66.7 39.9 39.6 189.4 42.4 94.0 43.4 100.7 55.0 20.9 23.6 22.1 24.7 20.1 24.1 24.0 25.5 23.5 21.4 21.9 25.1 34.7 57.7 79.6 82.3 108.9 59.9 106.3 82.7 21.6 32.7 73.0 71.5 27.3 42.9 69.2 46.0 12.5 43.1 54.8 50.4 60.7 58.8 18.0 47.2 42.3 46.7 47.4 63.8 49.9 40.5 82.9 67.8 28.5 52.4 59.5 17.0 28.2 58.1 45.6 21.9 60.9 29.3 71.2 71.5 194.0 10.0 52.8 106.8 72.9 120.9 177.7 33.5 40.2 63.3 87.4 56.0 43.9 26.4 57.1 81.8 34.4 46.5 66.2 37.4 26.3 52.1 40.3 54.3 33.9 29.3 60.9 134.9 109.3 33.0 32.2 158.4 PSMD14 "pad1, POH1, Rpn11" ENSG00000115233 "Proteasome 26S subunit, non-ATPase 14" O00487 2 161308425-161411717 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002114, HPA003828" Approved Supported Nucleoplasm NA NA 26000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA002114: AB_1855850, HPA003828: AB_2667057" "unprognostic (3.50e-3)" "unprognostic (1.48e-1)" "unprognostic (9.61e-2)" "unprognostic (6.63e-2)" "unprognostic (2.57e-1)" "unprognostic (7.61e-3)" "prognostic unfavorable (2.66e-8)" "unprognostic (3.11e-2)" "unprognostic (4.04e-2)" "unprognostic (3.90e-3)" "unprognostic (9.84e-3)" "unprognostic (3.02e-1)" "prognostic unfavorable (3.10e-6)" "unprognostic (2.86e-2)" "unprognostic (4.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.66e-1)" 35.2 38.3 38.6 39.7 40.0 38.8 36.4 42.5 47.5 26.2 36.7 35.2 29.1 24.7 30.1 40.7 27.3 23.7 44.6 40.7 43.3 44.4 48.4 26.9 37.8 42.1 41.7 14.5 25.6 51.1 21.4 42.0 43.7 31.0 41.0 37.9 20.8 29.9 98.0 33.2 26.4 39.6 43.8 22.9 27.2 38.7 41.1 49.7 34.7 76.0 52.0 42.5 19.6 46.6 170.3 145.8 158.8 140.8 113.9 97.0 194.2 173.6 168.2 246.1 198.6 216.2 140.2 200.2 258.0 128.7 144.3 126.5 176.8 185.6 244.6 210.3 133.1 200.8 110.8 245.9 139.7 196.7 113.8 74.4 138.8 277.4 256.8 94.0 185.5 117.1 222.1 139.6 207.7 164.1 145.0 148.0 220.5 124.3 218.2 123.6 154.4 196.0 218.6 145.0 138.4 101.3 117.8 131.7 167.5 131.4 90.2 124.3 147.2 162.7 152.4 111.6 193.8 82.5 242.7 186.7 174.1 129.6 182.2 47.4 48.2 25.2 65.3 69.6 68.7 64.2 69.4 71.0 75.4 57.4 55.4 66.5 4.9 70.2 56.2 74.5 83.7 73.3 38.6 40.0 42.5 47.5 40.7 43.3 42.1 41.7 43.7 43.8 41.1 46.6 40.1 51.3 38.2 35.3 49.4 49.5 48.1 146.8 25.0 43.7 40.2 36.2 89.8 52.9 80.3 23.9 18.8 159.5 60.4 47.7 90.1 124.3 82.5 52.4 51.8 49.9 52.5 56.2 64.0 118.3 154.6 48.1 29.6 58.4 51.2 59.0 31.8 125.3 104.7 47.1 56.1 53.5 118.0 41.1 40.0 36.0 27.7 46.1 48.0 25.3 61.1 87.7 44.3 50.3 64.6 155.0 48.0 34.3 60.2 57.0 36.5 106.1 55.4 60.6 32.9 36.6 64.5 137.0 77.7 34.3 56.0 220.3 47.8 63.6 64.5 50.8 TBR1 ENSG00000136535 "T-box brain transcription factor 1" Q16650 2 161416297-161425870 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 29.1" "Group enriched" "Detected in some" 5 "Early spermatids: 32.3;Late spermatids: 65.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 196 "amygdala: 9.2;basal ganglia: 27.4;cerebral cortex: 29.1;hippocampal formation: 13.0;white matter: 19.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "amygdala: 44.6;basal ganglia: 28.3;cerebral cortex: 70.8;hippocampal formation: 45.7;white matter: 43.9" "Region enhanced" "Detected in many" "cerebral cortex: 66.9" "HPA051256, HPA078644, HPA078657" Enhanced Supported NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "HPA051256: , HPA078644: AB_2732387, HPA078657: AB_2732388" "unprognostic (3.08e-2)" "unprognostic (5.45e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-2)" "unprognostic (7.43e-3)" "unprognostic (1.95e-1)" "unprognostic (1.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.39e-9)" "unprognostic (5.72e-2)" "unprognostic (1.72e-1)" "unprognostic (5.37e-2)" 0.0 0.0 9.2 0.0 27.4 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 27.4 0.0 29.1 13.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 32.3 0.2 0.3 0.4 0.0 0.0 9.3 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 65.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.3 0.2 0.5 1.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 SLC4A10 "NBCn2, NCBE" ENSG00000144290 "Solute carrier family 4 member 10" Q6U841 2 161424332-161985282 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.3;choroid plexus: 121.4;retina: 34.3" "Group enriched" "Detected in some" 4 "Excitatory neurons: 604.4;Inhibitory neurons: 560.9" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Region enhanced" "Detected in many" "cerebral cortex: 21.3" "Immune cell enriched" "Detected in some" 8 "MAIT T-cell: 63.3" "Lineage enriched" "Detected in single" 65 "T-cells: 63.3" "Cell line enriched" "Detected in single" 11 "Karpas-707: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034755, HPA076725" Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034755: AB_10670296, HPA076725: " "unprognostic (4.64e-4)" "unprognostic (3.88e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-2)" "unprognostic (1.19e-2)" "unprognostic (7.89e-3)" "unprognostic (5.99e-4)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.64e-1)" "unprognostic (2.50e-2)" "unprognostic (9.27e-2)" "unprognostic (5.65e-2)" "unprognostic (9.23e-3)" "unprognostic (1.87e-1)" "unprognostic (2.10e-3)" "unprognostic (2.26e-1)" 0.0 2.0 6.3 0.7 10.3 0.2 0.2 0.2 21.3 0.1 121.4 1.8 0.3 0.0 1.3 0.0 0.6 0.4 0.0 11.8 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.3 0.0 0.0 0.2 1.3 34.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.5 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 2.5 0.0 63.3 0.0 1.2 7.8 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.5 6.3 10.3 0.2 21.3 11.8 1.1 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.0 0.0 21.2 0.1 0.0 0.0 0.0 0.0 116.3 0.0 0.0 0.6 0.0 0.0 0.0 8.4 0.0 2.6 1.1 0.0 0.0 18.3 0.0 0.0 0.3 0.0 0.0 604.4 0.0 0.0 0.0 0.5 0.0 2.5 0.0 1.8 0.6 0.0 0.0 560.9 2.8 0.0 0.6 0.0 10.5 0.0 0.1 0.0 16.9 0.5 2.8 1.0 129.2 16.5 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 9.4 0.0 0.3 0.0 DPP4 "ADCP2, CD26, DPPIV" ENSG00000197635 "Dipeptidyl peptidase 4" P27487 2 161992245-162074394 "CD markers, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Aminopeptidase, Hydrolase, Protease, Receptor, Serine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 137.9;parathyroid gland: 155.7;placenta: 134.1;prostate: 107.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 140.3;Proximal enterocytes: 291.1;Proximal tubular cells: 101.4;Syncytiotrophoblasts: 172.0" "Cancer enhanced" "Detected in all" "prostate cancer: 55.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 52.3" "Lineage enriched" "Detected in many" 10 "T-cells: 52.3" "Cell line enhanced" "Detected in many" "ASC diff: 194.4;ASC TERT1: 212.6;BJ hTERT+: 207.0;RPTEC TERT1: 263.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045970, HPA068778, HPA071236" Enhanced "Secreted to blood" NA NA 190000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB045970: AB_11140529, HPA068778: , HPA071236: " "unprognostic (4.47e-2)" "unprognostic (4.47e-2)" "unprognostic (8.89e-2)" "unprognostic (3.36e-1)" "unprognostic (7.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.78e-1)" "unprognostic (3.54e-2)" "unprognostic (3.58e-1)" "unprognostic (4.73e-1)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.98e-4)" "prognostic favorable (1.35e-6)" "unprognostic (4.68e-2)" "unprognostic (6.33e-2)" "prognostic favorable (4.99e-4)" "unprognostic (1.21e-2)" 13.3 3.1 0.2 5.3 0.2 0.6 8.4 0.1 0.6 10.9 0.1 14.6 107.0 3.6 4.0 3.0 7.4 6.7 3.4 0.2 0.1 94.9 57.2 16.0 5.8 0.2 0.2 3.5 3.5 155.7 0.1 134.1 0.3 107.3 16.9 0.1 84.5 23.5 1.5 5.7 137.9 3.0 0.1 11.2 7.6 1.3 0.8 12.4 5.0 3.9 4.4 5.7 3.5 0.4 0.2 0.2 1.0 0.0 194.4 212.6 0.6 37.7 207.0 10.9 37.2 38.0 1.0 0.0 13.6 71.0 30.2 1.1 0.4 0.0 6.2 12.3 0.0 0.0 0.0 57.1 77.0 0.0 0.0 22.0 0.1 66.3 0.5 9.1 6.6 0.7 0.0 0.0 3.6 0.0 3.6 0.5 2.0 1.3 72.7 0.0 0.0 0.6 263.3 0.0 0.1 0.4 0.0 0.0 0.0 4.4 0.0 0.3 37.0 21.8 1.1 0.7 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 6.6 0.0 52.3 0.2 16.2 10.7 1.2 0.0 15.7 6.6 0.4 5.3 0.0 4.0 2.0 4.7 0.2 0.2 0.1 0.6 0.2 0.1 0.2 0.2 0.3 0.1 0.8 0.4 10.8 6.4 26.0 0.3 2.1 4.1 0.4 0.1 0.0 1.8 0.2 0.8 3.3 12.8 2.8 14.7 10.4 140.3 10.4 27.4 1.9 3.0 15.0 2.3 7.1 9.4 55.2 0.4 31.6 0.0 59.1 35.3 2.0 68.0 13.9 5.3 9.3 34.5 14.5 0.0 6.3 16.4 0.0 0.9 7.6 7.9 0.0 4.8 5.4 3.7 1.1 0.0 1.0 2.5 0.7 1.4 23.8 0.0 2.1 32.7 291.1 101.4 2.2 0.1 0.0 2.1 1.5 4.0 1.1 0.1 4.1 172.0 25.8 29.2 29.1 0.3 GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1943.6" "Cell type enriched" "Detected in some" 23 "Enteroendocrine cells: 5457.0" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Region enriched" "Detected in single" 55 "medulla oblongata: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 133.4;U-2 OS: 186.8;U-698: 44.5" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 13.7" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 127000 420000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" 20.3 0.1 0.0 3.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 84.4 3.4 0.6 0.0 5.3 0.0 4.1 2.5 0.0 0.0 41.9 0.0 0.2 3.5 6.2 0.0 0.1 1943.6 0.0 0.0 0.1 0.1 0.8 151.9 0.0 0.3 0.0 0.0 37.2 130.2 0.8 0.0 0.2 41.2 0.0 0.0 0.4 0.6 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 186.8 0.2 12.1 0.0 5.6 44.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.2 0.0 0.0 0.3 0.1 5457.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 230.9 8.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.9 0.0 FAP DPPIV ENSG00000078098 "Fibroblast activation protein alpha" Q12884 2 162170684-162245151 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.4;smooth muscle: 26.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 67.6;Fibroblasts: 43.4;Microglial cells: 17.8;Muller glia cells: 57.5;Smooth muscle cells: 25.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 192.2;ASC TERT1: 202.3;BJ hTERT+: 167.8;hTERT-RPE1: 209.1;U-138 MG: 167.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebral cortex: 3.1;hippocampal formation: 2.4" HPA059739 Uncertain "Secreted to blood" NA NA 108000000 56000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA059739: AB_2684117" "unprognostic (7.48e-3)" "unprognostic (7.87e-3)" "unprognostic (4.10e-2)" "unprognostic (5.04e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (4.82e-4)" "unprognostic (2.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.30e-2)" "unprognostic (4.89e-2)" "unprognostic (4.59e-2)" "unprognostic (3.52e-1)" "unprognostic (7.32e-11)" "unprognostic (1.72e-3)" "unprognostic (9.84e-3)" "unprognostic (7.97e-2)" "unprognostic (4.49e-3)" 5.8 0.2 0.9 5.2 0.9 0.0 10.1 0.4 0.9 15.2 0.0 3.5 0.5 31.4 8.5 3.6 4.8 22.3 4.9 0.3 1.4 0.7 0.2 4.0 1.5 0.6 0.5 3.0 2.5 0.7 0.5 23.1 0.6 1.9 2.5 6.4 4.7 5.8 4.4 2.8 0.9 26.4 0.2 0.4 1.0 1.5 1.0 0.5 2.8 7.5 1.5 15.5 3.6 0.7 0.0 0.0 0.0 0.0 192.2 202.3 0.4 82.8 167.8 16.6 25.4 0.0 0.0 0.0 0.6 31.3 0.0 0.1 0.0 5.1 8.0 0.0 0.0 0.1 1.2 0.0 19.5 0.0 0.0 66.2 1.2 28.1 5.2 209.1 0.1 0.0 0.0 0.0 53.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.5 0.0 9.0 0.2 0.1 0.0 84.3 167.3 3.1 41.4 0.4 0.0 0.1 0.0 37.5 0.1 45.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.4 0.9 0.3 1.4 0.6 0.5 0.6 0.2 1.0 0.7 3.9 0.0 0.0 5.5 0.2 4.5 0.1 7.0 0.0 1.8 0.3 0.5 0.4 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.2 6.7 3.4 67.6 6.4 4.9 0.0 13.3 0.2 1.9 43.4 0.0 6.2 0.0 0.0 1.4 0.0 0.9 1.7 0.3 1.4 0.0 0.0 2.6 4.1 8.4 0.8 3.6 17.8 0.0 57.5 0.0 0.5 4.2 1.0 0.0 0.0 0.3 0.0 0.0 1.2 0.2 2.0 0.0 4.7 25.2 2.3 0.4 0.4 4.3 1.8 0.8 1.3 0.2 0.0 IFIH1 "Hlcd, IDDM19, MDA-5, MDA5" ENSG00000115267 "Interferon induced with helicase C domain 1" Q9BYX4 2 162267074-162318684 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.1" "Cell type enhanced" "Detected in many" "Early spermatids: 55.6;Late spermatids: 53.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 62.3;BJ hTERT+ SV40 Large T+ RasG12V: 71.5;Karpas-707: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002656 Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA002656: AB_1079344" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (5.51e-2)" "unprognostic (3.85e-3)" "unprognostic (3.34e-1)" "unprognostic (1.39e-1)" "unprognostic (5.65e-2)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.86e-2)" "unprognostic (1.53e-2)" "unprognostic (2.62e-1)" "unprognostic (1.72e-1)" "unprognostic (1.57e-1)" "unprognostic (1.27e-1)" "unprognostic (4.41e-2)" "unprognostic (7.29e-2)" 6.2 6.4 3.1 12.7 4.3 38.1 5.9 3.2 3.0 6.5 4.4 7.4 13.1 6.4 4.3 7.5 7.2 9.5 5.1 2.3 3.3 5.6 8.5 10.9 11.7 7.2 3.4 7.0 7.1 8.1 5.9 8.3 5.0 5.5 6.8 1.1 17.5 4.7 1.7 5.0 10.0 5.7 8.1 16.4 9.6 2.4 4.2 10.9 6.0 3.2 9.7 6.4 5.2 4.4 6.7 0.3 0.2 0.0 7.4 6.0 2.8 1.2 17.7 62.3 71.5 1.2 16.7 13.3 10.5 1.0 31.9 8.5 1.1 9.8 6.3 35.4 4.5 7.1 0.8 2.8 5.0 8.2 6.4 5.3 4.8 8.9 1.7 6.5 4.9 6.9 0.3 38.9 1.0 12.5 9.3 6.4 0.0 5.4 3.8 7.5 0.0 18.8 5.9 7.3 0.4 0.1 3.7 20.7 34.0 0.3 5.7 7.1 4.1 1.9 1.7 1.1 2.7 15.2 26.8 1.9 3.5 6.5 5.6 4.4 11.5 4.4 6.6 12.5 9.2 12.4 8.2 7.2 11.1 12.8 6.7 6.9 15.2 4.0 12.7 1.6 10.3 7.8 3.1 4.3 3.2 3.0 2.3 3.3 7.2 3.4 5.0 8.1 4.2 4.4 24.7 32.1 12.0 4.6 20.1 6.8 11.2 7.7 6.2 0.0 4.8 5.2 5.0 12.8 11.1 7.3 0.0 6.4 10.2 10.9 5.9 18.7 55.6 17.3 7.9 22.3 15.7 8.2 2.8 18.7 17.5 8.8 10.7 20.2 13.3 10.4 13.6 6.5 14.4 0.0 0.7 11.5 8.2 12.8 8.7 53.3 13.7 20.0 5.4 28.1 23.9 7.3 10.3 0.5 4.0 13.4 10.1 13.2 16.0 9.1 11.8 4.8 17.5 0.1 0.0 10.9 4.9 1.6 1.3 10.2 5.8 3.4 13.1 6.9 6.7 11.1 GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in all" "Early spermatids: 185.0;Kupffer cells: 183.3;Macrophages: 153.5;monocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" 30.5 13.5 16.4 62.6 23.0 325.7 17.6 20.2 28.8 12.2 11.4 18.0 19.3 9.8 24.6 10.9 16.2 23.0 9.7 15.9 17.7 18.3 15.0 26.5 33.0 25.5 20.7 8.5 16.6 10.4 8.2 25.2 23.6 12.2 19.6 10.6 12.3 9.7 2.7 7.0 18.7 18.8 21.6 70.1 25.1 24.1 19.5 18.4 17.0 14.9 25.4 26.1 5.7 37.3 2.6 4.2 10.7 0.0 2.5 2.2 0.4 4.0 11.1 6.2 11.1 8.7 30.6 3.7 27.0 0.3 14.2 1.6 4.1 12.7 7.7 17.1 16.8 33.5 2.9 17.7 3.0 41.6 9.1 2.8 4.3 5.7 1.2 15.8 0.9 25.9 0.6 12.1 0.5 33.0 0.9 24.2 6.5 22.5 16.4 14.2 2.7 18.5 32.7 18.6 6.9 12.0 5.1 23.3 19.7 12.5 15.8 17.7 0.8 1.6 11.2 17.8 6.2 11.5 23.2 0.6 9.2 15.8 7.7 38.8 132.4 327.4 2.7 78.4 3.5 21.6 4.8 4.8 63.2 21.1 8.1 5.0 864.2 2.5 63.3 17.2 10.2 71.4 16.4 23.0 20.2 28.8 15.9 17.7 25.5 20.7 23.6 21.6 19.5 37.3 28.8 16.0 36.5 10.1 54.5 15.4 28.2 19.6 12.5 10.2 32.6 16.4 4.1 50.1 21.2 33.1 2.1 55.5 17.3 14.4 76.3 49.5 185.0 21.1 9.1 26.4 39.4 36.1 25.9 60.5 20.8 14.4 43.8 24.9 44.9 13.6 48.9 15.0 107.9 11.8 15.4 29.9 32.6 183.3 60.5 32.8 10.8 153.5 16.0 17.8 228.5 21.1 10.3 1.0 98.0 36.5 25.7 6.4 23.4 24.3 18.4 69.7 24.7 4.4 6.6 12.2 18.3 52.6 13.5 15.1 18.2 46.9 16.3 16.7 28.9 21.0 KCNH7 "erg3, HERG3, Kv11.3" ENSG00000184611 "Potassium voltage-gated channel subfamily H member 7" Q9NS40 2 162371407-162838767 "FDA approved drug targets, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.9;retina: 1.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 685.6;Inhibitory neurons: 352.4" "Not detected" "Not detected" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SCLC-21H: 6.0;SK-BR-3: 5.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 53.0" HPA018039 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA018039: AB_1852125" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.66e-1)" "unprognostic (5.55e-2)" "unprognostic (3.05e-2)" "unprognostic (5.51e-2)" "unprognostic (8.12e-3)" "unprognostic (7.31e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (7.55e-3)" "unprognostic (2.76e-3)" "unprognostic (2.13e-1)" "unprognostic (4.71e-2)" "unprognostic (1.68e-2)" 0.0 0.1 0.7 0.1 0.8 0.1 0.0 1.2 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.4 0.0 5.8 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.8 1.2 5.9 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.1 0.0 0.0 685.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.1 21.9 352.4 0.0 0.0 0.6 0.0 68.3 0.0 0.1 0.0 4.7 0.0 0.2 0.0 20.1 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Inhibitory neurons: 82.9;Oligodendrocyte precursor cells: 309.6;Oligodendrocytes: 129.4;Sertoli cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 3.3" "Lineage enriched" "Detected in single" 34 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "AF22: 18.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034987, HPA057919" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA034987: AB_10669681, HPA057919: " "unprognostic (3.93e-2)" "unprognostic (8.30e-3)" "unprognostic (1.48e-1)" "unprognostic (7.68e-5)" "unprognostic (3.45e-2)" "unprognostic (8.98e-4)" "unprognostic (5.23e-3)" "unprognostic (7.65e-3)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-2)" "unprognostic (3.24e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (4.10e-2)" "unprognostic (3.78e-2)" 3.1 2.0 3.9 0.4 5.0 0.8 2.0 2.3 4.4 2.4 0.0 2.6 0.4 1.1 1.2 0.6 1.9 1.1 3.3 2.5 5.4 1.9 3.2 1.4 0.6 3.0 4.2 4.6 2.9 0.4 2.6 1.1 3.9 1.6 0.7 1.4 2.6 2.7 1.0 1.0 1.4 0.9 1.8 3.0 1.8 1.1 4.6 0.2 1.1 1.7 0.2 1.7 2.4 5.1 6.4 2.3 18.6 0.0 0.0 0.0 6.8 2.4 1.6 1.7 3.2 0.0 2.2 0.0 6.6 2.6 3.4 0.9 6.2 2.6 1.3 0.0 4.6 0.0 4.7 4.6 1.5 0.0 0.0 0.8 2.2 3.3 9.0 2.6 4.0 0.0 0.0 0.0 5.1 1.6 0.0 0.0 7.9 0.4 2.9 0.0 6.3 0.0 4.2 2.1 2.9 2.5 0.0 1.8 1.7 10.3 2.0 0.0 0.4 7.6 6.8 0.0 5.1 1.1 0.0 0.0 2.3 0.0 4.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.0 2.3 4.4 2.5 5.4 3.0 4.2 3.9 1.8 4.6 5.1 2.9 6.4 7.3 161.3 0.7 1.9 0.1 2.8 1.8 24.4 5.7 2.7 19.4 20.0 3.0 12.9 0.0 21.2 0.2 0.1 1.9 3.7 3.8 0.7 0.7 2.1 0.0 0.0 53.4 1.5 7.4 11.6 4.1 1.6 0.0 23.6 7.9 13.5 1.4 6.7 82.9 0.0 4.1 0.0 1.6 6.4 51.9 0.6 17.8 28.1 0.0 4.3 0.0 309.6 129.4 1.1 0.0 34.3 0.0 1.8 0.0 8.1 4.0 2.1 72.3 16.6 17.8 1.1 1.2 1.0 0.4 16.8 0.2 7.0 0.0 0.0 GRB14 ENSG00000115290 "Growth factor receptor bound protein 14" Q14449 2 164492417-164621482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 12.6;tongue: 20.3" "Group enriched" "Detected in many" 4 "Distal tubular cells: 92.0;Granulosa cells: 272.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.5" "Region enhanced" "Detected in single" "hippocampal formation: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.5;HUVEC TERT2: 9.6;RPTEC TERT1: 9.1;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022294, HPA035052, HPA035053" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" "CAB022294: , HPA035052: , HPA035053: AB_2674432" "unprognostic (2.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.74e-2)" "unprognostic (6.75e-2)" "unprognostic (7.47e-2)" "unprognostic (8.33e-5)" "unprognostic (5.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (8.33e-3)" "unprognostic (2.71e-1)" "unprognostic (1.89e-3)" "unprognostic (7.10e-2)" "unprognostic (5.19e-2)" "unprognostic (9.27e-2)" 0.7 3.0 0.0 0.3 0.4 0.0 0.3 0.0 0.6 0.1 0.1 0.9 0.9 0.2 5.4 1.2 0.1 0.1 2.7 1.3 0.1 6.6 12.6 0.4 0.0 0.3 0.2 2.0 4.7 0.0 0.3 1.7 0.0 0.3 0.3 0.4 0.3 0.3 2.4 0.2 0.2 0.4 0.0 0.2 0.2 2.6 0.3 0.0 0.9 20.3 0.0 0.0 0.1 0.0 0.8 5.5 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 2.5 0.5 0.0 2.9 0.0 0.9 0.3 0.8 1.2 0.3 0.0 4.1 0.0 0.3 1.3 0.1 0.0 0.0 0.3 0.8 1.8 0.0 1.6 9.6 0.0 0.0 0.0 1.5 2.1 0.0 0.0 1.9 0.2 1.2 0.0 0.0 0.1 9.1 0.4 3.1 0.3 0.0 0.3 0.0 1.1 0.7 0.0 11.8 0.1 1.2 0.0 0.1 0.4 0.1 0.0 2.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.6 1.3 0.1 0.3 0.2 0.0 0.0 0.3 0.0 4.5 0.0 5.4 0.7 0.1 0.1 0.3 0.0 0.0 1.3 1.6 1.4 17.7 22.8 0.0 16.5 0.0 0.2 1.3 0.3 92.0 13.5 1.5 0.6 0.2 3.0 0.0 0.0 24.5 3.3 0.2 2.4 0.0 1.9 0.0 272.4 1.1 40.4 0.0 0.0 6.2 2.6 0.0 1.0 0.3 4.4 9.3 3.2 19.6 1.9 1.0 0.3 0.0 3.5 2.3 4.0 0.0 17.3 0.0 0.8 0.3 14.7 0.0 0.8 13.1 0.8 10.9 0.7 6.4 0.1 0.0 0.1 0.2 30.4 1.6 0.2 COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 218.8;Cone photoreceptor cells: 250.2;Microglial cells: 351.3;Syncytiotrophoblasts: 331.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.4;plasmacytoid DC: 8.1" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.1" "Cell line enhanced" "Detected in many" "Karpas-707: 62.6;RPTEC TERT1: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "HPA044933: AB_2679148, HPA053344: AB_2682123" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.38e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.27e-13)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "unprognostic (1.42e-1)" 35.1 51.4 9.5 7.4 8.5 4.1 13.8 6.4 9.2 10.1 28.7 8.0 10.7 4.6 15.6 32.6 4.8 12.3 7.2 6.6 7.1 68.8 107.6 18.2 12.8 8.9 7.9 12.5 43.7 10.9 5.0 50.9 9.4 27.4 7.8 56.8 17.9 28.0 3.3 16.9 7.8 7.4 6.8 9.9 30.0 2.0 12.8 4.8 18.4 7.2 16.2 22.6 16.4 6.3 10.7 2.2 5.9 0.0 7.1 1.3 11.9 34.0 13.3 4.7 5.6 8.9 4.3 1.0 6.9 3.2 5.0 38.4 26.2 21.3 5.6 2.9 10.7 10.5 9.5 36.3 10.2 0.0 0.0 1.8 19.8 1.0 27.6 5.8 21.1 1.3 0.0 62.6 7.5 12.5 0.3 0.1 2.9 25.9 12.8 1.3 22.4 10.4 63.1 36.0 14.4 5.8 16.1 14.7 4.6 11.4 10.7 0.0 9.5 11.3 9.7 3.8 8.3 24.3 10.0 3.6 4.7 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.8 0.0 8.1 0.0 0.4 9.5 8.5 6.4 9.2 6.6 7.1 8.9 7.9 9.4 6.8 12.8 6.3 56.4 70.5 66.5 7.5 102.5 97.3 54.3 14.5 30.7 21.6 22.4 22.4 9.3 30.0 26.0 218.8 250.2 52.1 40.8 11.3 62.6 25.5 0.1 24.6 12.2 47.1 22.2 22.5 23.7 33.8 71.3 35.0 53.5 19.5 34.1 9.0 6.1 127.9 8.7 3.3 30.9 11.0 24.4 3.9 9.0 1.3 14.6 3.7 19.6 351.3 0.7 144.5 0.0 5.0 1.6 29.8 4.9 7.9 154.8 46.0 12.6 28.6 12.4 190.2 46.0 8.6 71.2 0.6 2.7 69.0 70.3 331.4 8.3 8.0 10.0 75.6 SLC38A11 "AVT2, FLJ39822" ENSG00000169507 "Solute carrier family 38 member 11" Q08AI6 2 164896186-164955525 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 28.7;epididymis: 38.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.6;Enteroendocrine cells: 174.1;Excitatory neurons: 53.4;Sertoli cells: 72.3;Smooth muscle cells: 39.8" "Cancer enriched" "Detected in many" 5 "prostate cancer: 7.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "memory B-cell: 1.6;naive B-cell: 3.9" "Lineage enriched" "Detected in single" 39 "B-cells: 3.9" "Cell line enriched" "Detected in some" 9 "BJ hTERT+: 249.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043432 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA043432: AB_10793948" "unprognostic (1.52e-1)" "unprognostic (2.59e-1)" "unprognostic (4.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-2)" "unprognostic (6.28e-3)" "unprognostic (3.53e-2)" "unprognostic (2.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-3)" "unprognostic (1.99e-1)" "prognostic favorable (2.00e-8)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (2.43e-2)" "unprognostic (2.36e-2)" 2.0 4.0 6.0 1.5 6.4 0.1 0.8 3.8 11.2 2.6 28.7 1.5 6.0 1.7 38.6 1.0 0.8 17.7 1.3 6.2 3.9 7.9 2.6 0.4 2.0 3.9 4.2 0.3 2.2 1.3 3.3 0.3 4.3 10.8 2.7 0.3 0.6 16.9 0.9 0.6 2.7 2.0 3.5 8.1 11.7 0.2 5.8 0.3 2.1 4.0 1.3 1.5 1.1 6.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 28.9 249.7 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.1 0.0 5.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.0 6.4 3.8 11.2 6.2 3.9 3.9 4.2 4.3 3.5 5.8 6.3 0.9 0.0 0.0 6.2 7.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.9 28.6 0.0 3.7 0.0 0.7 2.7 0.5 0.0 3.2 2.1 0.1 0.5 2.7 174.1 2.7 53.4 0.6 0.6 0.3 5.1 0.1 0.0 0.0 0.4 3.7 0.0 0.0 2.9 6.4 0.0 0.0 0.3 1.2 0.0 0.0 0.0 17.8 0.0 0.1 0.0 0.5 1.2 0.8 2.3 0.0 0.0 3.2 1.0 2.0 0.0 0.1 72.3 0.5 39.8 0.1 0.0 0.2 0.3 1.5 0.9 4.4 0.7 0.2 SCN3A Nav1.3 ENSG00000153253 "Sodium voltage-gated channel alpha subunit 3" Q9NY46 2 165087526-165204050 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 16.9" "Cell type enhanced" "Detected in some" "Early spermatids: 78.4;Excitatory neurons: 227.3;Inhibitory neurons: 169.4;Oligodendrocyte precursor cells: 358.4" "Cancer enriched" "Detected in some" 6 "glioma: 3.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 13.2;naive B-cell: 15.3" "Lineage enriched" "Detected in single" 32 "B-cells: 15.3" "Cell line enhanced" "Detected in some" "JURKAT: 5.9;Karpas-707: 10.3;MOLT-4: 30.3;RPTEC TERT1: 14.9;SH-SY5Y: 6.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035396 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA035396: AB_2674607" "unprognostic (1.80e-3)" "unprognostic (1.84e-2)" "unprognostic (1.20e-3)" "unprognostic (1.50e-2)" "unprognostic (6.69e-2)" "unprognostic (1.10e-2)" "unprognostic (4.96e-4)" "unprognostic (2.46e-1)" "unprognostic (1.48e-1)" "unprognostic (1.90e-1)" "unprognostic (1.21e-4)" "unprognostic (4.55e-2)" "unprognostic (5.87e-3)" "unprognostic (2.88e-2)" "unprognostic (6.85e-2)" "unprognostic (2.66e-1)" "unprognostic (4.93e-2)" 1.0 1.5 10.9 0.5 10.9 0.2 1.0 7.2 12.1 0.6 0.0 0.6 0.3 0.4 0.1 0.4 0.4 0.5 0.6 10.1 16.9 0.5 0.2 0.2 0.8 6.0 8.8 0.6 0.5 0.4 0.1 0.1 9.2 0.2 0.7 1.0 0.1 0.4 0.9 0.0 0.5 0.5 3.0 0.5 0.9 0.5 13.4 3.1 0.2 0.6 1.2 0.5 0.0 6.5 0.0 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.3 0.6 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 4.9 0.0 5.9 0.0 10.3 0.1 0.0 30.3 0.0 0.0 0.1 2.4 0.1 1.3 0.0 14.9 0.0 3.8 6.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.2 0.1 0.8 0.0 1.4 0.6 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 15.3 0.1 0.0 0.0 0.2 0.0 0.4 0.1 0.1 10.9 10.9 7.2 12.1 10.1 16.9 6.0 8.8 9.2 3.0 13.4 6.5 0.9 0.0 0.5 8.5 6.5 0.0 0.2 0.0 0.6 4.4 0.1 0.4 6.5 0.0 0.0 1.8 12.5 0.0 0.0 0.0 0.0 0.2 78.4 0.0 0.0 2.9 8.9 0.0 227.3 0.0 0.0 0.5 1.1 0.0 0.0 0.3 0.0 0.2 0.1 5.0 169.4 1.2 0.0 0.0 0.3 11.5 0.3 0.2 1.8 19.7 0.0 0.3 0.0 358.4 9.2 0.1 0.0 0.7 5.3 0.0 0.0 0.0 0.0 0.8 13.1 0.3 31.8 0.7 2.4 0.0 0.1 0.0 0.1 0.3 0.1 0.1 SCN2A "HBSCI, HBSCII, Nav1.2, SCN2A1, SCN2A2" ENSG00000136531 "Sodium voltage-gated channel alpha subunit 2" Q99250 2 165194993-165392310 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 26.1" "Group enriched" "Detected in some" 5 "Excitatory neurons: 440.4;Inhibitory neurons: 364.7;Oligodendrocyte precursor cells: 246.3" "Cancer enhanced" "Detected in single" "glioma: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 2.1;U-138 MG: 3.4;U-266/84: 8.1;U-87 MG: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022567 Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB022567: " "unprognostic (1.16e-1)" "unprognostic (3.56e-4)" "unprognostic (5.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.97e-1)" "unprognostic (8.62e-3)" "unprognostic (1.18e-1)" "unprognostic (7.25e-3)" "unprognostic (1.40e-1)" "unprognostic (2.78e-1)" "unprognostic (1.32e-2)" "unprognostic (5.21e-2)" "unprognostic (3.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-1)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" 0.2 1.3 15.8 0.1 17.5 0.0 0.7 26.1 20.1 0.2 0.0 0.1 0.2 0.5 0.9 0.0 0.1 0.8 0.1 22.2 8.0 3.5 0.1 0.2 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.1 0.0 0.1 0.1 4.6 0.2 0.4 0.0 0.0 0.2 0.6 0.0 0.1 0.3 0.3 2.5 0.3 0.0 0.0 0.0 0.1 0.3 5.8 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.7 0.4 0.0 0.2 0.0 0.3 0.0 0.1 2.1 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.2 0.9 0.0 0.1 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.2 0.2 0.0 0.3 8.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 17.5 26.1 20.1 22.2 8.0 0.0 0.0 0.0 0.0 2.5 5.8 0.1 0.0 1.7 18.3 0.5 0.3 0.1 0.2 0.0 49.8 0.3 4.7 0.8 0.0 0.0 11.0 47.9 0.1 0.2 0.0 5.9 0.2 1.6 0.1 2.3 0.3 0.0 0.0 440.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.2 364.7 0.0 0.0 0.0 0.0 1.4 1.2 0.0 0.0 60.9 0.0 3.4 0.0 246.3 17.0 0.3 0.0 6.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 0.6 0.0 0.9 0.1 0.1 0.0 0.4 1.0 0.0 0.0 CSRNP3 "FAM130A2, FLJ32093, PPP1R73, TAIP-2" ENSG00000178662 "Cysteine and serine rich nuclear protein 3" Q8WYN3 2 165469647-165689407 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 358.3;Inhibitory neurons: 315.3;Oligodendrocyte precursor cells: 344.8;Oligodendrocytes: 95.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.8;PC-3: 2.4;SCLC-21H: 7.1;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017905 Approved Uncertain "Nucleoplasm,Nucleoli rim" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli rim" Nucleoplasm "HPA017905: AB_1857757" "unprognostic (2.85e-1)" "unprognostic (1.65e-2)" "unprognostic (1.39e-2)" "unprognostic (1.11e-1)" "unprognostic (1.27e-1)" "unprognostic (3.61e-1)" "unprognostic (8.87e-2)" "unprognostic (1.02e-2)" "unprognostic (2.18e-2)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (1.82e-3)" "unprognostic (7.41e-2)" "unprognostic (5.36e-2)" "unprognostic (3.17e-1)" "unprognostic (1.08e-2)" 0.9 2.3 9.4 0.4 9.3 0.0 3.2 0.0 14.4 2.3 7.0 0.8 0.7 2.7 0.8 0.7 0.9 0.9 1.4 10.6 10.5 1.5 0.6 0.4 0.2 0.0 0.7 3.4 3.7 1.1 3.4 0.2 0.0 1.5 0.9 6.4 2.2 2.1 0.1 0.7 0.6 2.5 0.0 0.8 0.7 0.6 8.6 0.5 2.3 0.7 0.2 0.6 1.0 6.5 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.4 0.0 0.3 0.1 0.5 0.0 0.2 0.0 0.7 0.4 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.4 0.0 0.0 0.6 0.5 0.0 7.1 5.8 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 9.3 0.0 14.4 10.6 10.5 0.0 0.7 0.0 0.0 8.6 6.5 2.5 3.2 5.1 81.6 0.2 5.2 4.0 2.3 6.8 55.7 16.2 13.5 8.7 5.7 1.6 11.0 70.9 0.3 0.0 0.7 3.9 2.7 2.9 2.3 9.6 3.6 7.7 0.0 358.3 2.3 0.1 8.2 2.0 2.3 0.0 47.9 1.4 3.6 2.6 11.8 315.3 4.7 4.1 0.3 1.6 1.7 7.5 0.4 7.2 7.5 0.0 19.6 0.0 344.8 95.4 0.9 1.9 8.2 0.0 0.6 1.7 7.2 0.5 20.4 6.6 4.4 23.0 0.6 1.6 6.3 4.5 0.3 0.2 13.2 2.6 2.0 GALNT3 "GalNAc-T3, HFTC, HHS" ENSG00000115339 "Polypeptide N-acetylgalactosaminyltransferase 3" Q14435 2 165747588-165794659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 77.3" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 152.8;Pancreatic endocrine cells: 188.1;Prostatic glandular cells: 155.7;Urothelial cells: 274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 50.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.4;HaCaT: 108.3;HBEC3-KT: 69.2;hTCEpi: 88.2;OE19: 201.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA007613 Enhanced Supported "Golgi apparatus" NA NA 440000 "Cluster 46: Basophils - DNA binding" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" "HPA007613: AB_1078941" "unprognostic (1.95e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.16e-3)" "unprognostic (2.78e-1)" "unprognostic (3.22e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (4.13e-2)" "unprognostic (4.47e-2)" "unprognostic (2.74e-1)" "unprognostic (6.44e-2)" "unprognostic (3.62e-3)" "unprognostic (1.33e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.57e-1)" 1.5 1.7 1.7 8.4 2.1 54.0 26.0 2.7 1.8 29.3 4.3 48.9 43.5 5.2 9.3 27.4 38.8 32.2 0.6 1.8 3.4 10.9 2.4 14.0 3.7 4.5 5.2 6.8 26.2 6.9 9.8 6.4 3.3 25.2 53.2 3.7 55.3 8.2 0.3 15.3 39.5 2.5 7.0 20.1 77.3 25.8 1.9 3.3 25.4 0.4 12.3 17.3 12.6 5.4 61.5 0.0 0.6 0.2 0.1 2.6 43.0 18.3 7.7 6.6 16.0 32.0 85.4 0.4 0.1 0.0 0.1 108.3 0.0 69.2 13.5 1.3 13.0 0.0 14.9 0.3 0.3 14.5 0.4 0.5 88.2 0.0 30.3 2.1 0.1 2.9 0.0 55.0 5.0 42.7 0.5 5.6 0.1 201.1 7.8 0.2 0.0 1.7 17.8 42.0 6.5 0.1 0.3 49.6 16.8 1.9 21.7 0.9 0.5 0.1 1.0 0.1 0.3 34.4 16.3 1.3 0.2 14.0 0.6 50.5 6.8 32.2 10.2 9.0 7.5 6.6 3.1 5.8 11.4 6.0 1.0 3.4 25.2 10.6 13.8 17.3 5.6 6.2 1.7 2.1 2.7 1.8 1.8 3.4 4.5 5.2 3.3 7.0 1.9 5.4 1.0 12.8 34.4 7.8 13.6 38.0 107.9 36.5 29.6 0.6 45.0 26.8 0.4 35.8 45.9 66.2 0.0 8.5 37.7 68.6 3.9 70.2 127.5 91.8 5.2 2.9 23.4 1.3 10.5 113.2 22.5 2.3 102.4 70.5 45.7 0.7 1.1 0.6 8.2 0.0 5.1 152.8 28.5 1.9 12.4 14.1 2.5 8.3 16.0 1.0 7.5 16.1 15.5 27.6 1.4 188.1 46.5 0.4 29.7 155.7 32.6 3.1 89.3 1.0 6.6 0.6 4.3 71.5 1.1 42.4 41.3 11.2 14.4 1.2 61.8 274.4 TTC21B "FAP60, FLA17, FLJ11457, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 67.8;Excitatory neurons: 81.2;Inhibitory neurons: 85.5;Oligodendrocyte precursor cells: 77.9;Oligodendrocytes: 58.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035495, HPA073293" Supported Approved Cytosol NA No "Cluster 38: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA035495: AB_10672866, HPA073293: " "unprognostic (1.63e-2)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" "unprognostic (1.60e-2)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "unprognostic (7.09e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (7.57e-2)" "unprognostic (3.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (1.84e-2)" 5.5 4.1 3.1 3.1 3.4 2.1 5.3 6.5 4.3 6.8 2.6 5.1 2.6 6.3 2.8 3.0 7.3 2.8 5.2 3.2 3.2 5.2 4.0 4.7 4.1 3.3 3.5 8.0 5.0 4.3 4.6 4.7 3.5 6.1 4.0 7.5 4.6 4.2 9.1 4.7 4.2 4.1 3.2 4.0 4.3 4.4 3.1 5.0 4.3 9.2 3.3 4.7 6.0 3.9 4.1 2.1 11.8 6.2 11.0 7.0 3.6 8.2 5.9 4.9 5.8 4.4 2.5 8.9 3.8 3.2 4.7 5.0 8.2 4.8 6.9 6.4 4.9 6.5 4.4 13.6 6.2 6.7 0.0 4.0 2.9 5.9 5.2 8.4 7.0 5.6 9.6 6.1 9.0 2.4 7.0 7.8 6.9 4.6 6.9 9.5 9.1 3.9 6.2 8.2 9.6 6.9 4.7 1.7 8.6 6.3 2.5 7.2 3.9 12.0 5.1 6.5 5.4 3.5 4.5 5.8 5.2 5.4 7.2 3.2 0.5 0.6 0.8 0.6 1.1 1.2 1.0 0.8 0.9 1.0 1.0 1.3 0.2 1.4 1.0 0.4 1.1 0.5 3.1 3.4 6.5 4.3 3.2 3.2 3.3 3.5 3.5 3.2 3.1 3.9 11.1 3.2 9.8 32.7 12.9 9.2 8.3 5.3 22.8 21.6 7.2 6.9 12.5 4.3 9.4 5.5 33.3 3.8 20.2 4.6 0.0 3.3 2.4 67.8 15.3 8.2 7.2 13.7 81.2 1.8 4.6 11.3 11.2 21.6 6.3 12.8 10.8 8.4 13.1 15.2 85.5 7.7 6.1 8.1 4.9 3.2 10.5 7.2 10.6 44.0 5.7 9.9 9.2 77.9 58.9 1.1 6.5 12.8 14.5 6.3 4.0 7.2 34.7 22.7 6.6 15.9 10.7 7.1 12.1 8.5 3.8 2.9 12.5 8.5 5.8 4.7 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 102.0;Leydig cells: 100.9;Peritubular cells: 159.9;Sertoli cells: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "HDLM-2: 7.9;HMC-1: 4.5;Karpas-707: 5.8;SK-BR-3: 15.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" 4.6 8.6 3.4 3.4 3.0 0.3 10.2 0.1 1.8 7.8 0.0 35.8 3.4 9.0 6.3 10.1 10.9 3.8 20.6 1.1 7.1 1.8 1.2 27.6 0.5 4.0 7.1 45.4 4.9 0.7 1.0 12.3 5.4 11.0 8.5 10.6 6.1 10.1 7.2 2.4 6.8 7.6 2.9 3.2 7.8 5.6 9.8 3.2 1.2 15.0 0.4 4.7 7.1 1.2 0.1 0.1 0.7 0.9 0.2 0.0 0.8 0.7 0.0 1.3 0.0 0.6 0.2 0.4 0.1 0.0 0.3 0.3 0.1 0.1 0.0 7.9 0.5 0.2 1.5 0.6 0.0 0.2 4.5 0.0 0.0 0.4 0.1 0.4 0.0 0.4 1.2 5.8 0.0 1.0 0.8 0.5 1.1 0.3 0.3 0.0 0.5 0.0 0.1 0.8 0.2 0.4 0.3 15.4 0.0 0.3 0.4 0.1 0.4 0.2 1.0 0.7 0.4 1.0 0.3 1.1 0.2 0.2 0.4 1.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.8 3.4 3.0 0.1 1.8 1.1 7.1 4.0 7.1 5.4 2.9 9.8 1.2 1.4 0.0 1.1 1.0 0.0 0.3 0.2 0.0 5.7 21.5 0.2 0.3 16.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 2.4 0.0 0.3 4.1 0.0 0.0 7.7 0.0 0.0 102.0 0.0 0.0 15.9 0.1 9.3 0.0 0.2 0.0 20.9 0.0 0.0 0.0 1.2 4.1 100.9 1.8 5.4 14.0 0.0 4.9 0.0 14.1 0.3 0.1 0.0 159.9 1.2 0.5 0.0 0.5 0.0 1.8 151.2 16.7 26.1 0.5 1.2 1.7 1.1 0.0 0.2 0.3 0.0 0.3 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 B3GALT1 beta3Gal-T1 ENSG00000172318 "Beta-1,3-galactosyltransferase 1" Q9Y5Z6 2 167868948-167874041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;skeletal muscle: 5.2;tongue: 17.8" "Group enriched" "Detected in some" 6 "Astrocytes: 920.7;Excitatory neurons: 519.3;Inhibitory neurons: 723.8" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "AN3-CA: 35.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.12e-2)" "unprognostic (7.22e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-3)" "unprognostic (2.49e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-1)" "unprognostic (3.94e-2)" "unprognostic (8.72e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-3)" "unprognostic (8.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (3.79e-1)" 0.2 0.5 4.0 0.2 5.4 0.1 0.4 2.0 5.8 0.3 0.0 3.6 0.0 0.2 0.4 0.1 0.6 0.0 0.0 5.8 3.0 0.1 0.0 0.1 0.0 2.4 2.9 0.2 0.3 0.0 1.8 0.0 1.4 0.2 3.6 2.4 0.2 0.7 5.2 0.2 0.2 0.2 2.0 0.2 0.0 0.5 2.6 0.0 0.2 17.8 0.0 0.0 0.2 3.4 0.0 0.0 2.8 35.7 0.3 0.0 0.0 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 4.6 0.0 1.2 0.0 0.2 0.0 0.5 0.0 2.3 0.4 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.0 0.8 0.0 0.7 0.0 3.3 0.5 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.3 0.2 0.2 0.1 0.0 0.1 0.1 0.0 4.0 5.4 2.0 5.8 5.8 3.0 2.4 2.9 1.4 2.0 2.6 3.4 0.2 0.0 1.3 920.7 0.2 0.1 0.0 0.0 0.0 3.0 0.1 2.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 18.3 0.0 0.1 0.5 0.1 0.6 0.7 0.0 0.0 519.3 0.2 0.0 0.5 0.0 0.4 1.3 0.0 0.0 0.0 0.1 1.7 723.8 3.8 0.0 0.0 0.3 0.0 0.6 0.3 1.8 39.4 0.0 2.4 0.0 108.0 30.3 0.0 3.4 1.5 0.0 0.4 0.0 0.4 0.0 1.3 0.0 1.1 0.6 0.0 1.7 0.0 0.0 0.0 0.1 0.1 7.4 0.1 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 CERS6 LASS6 ENSG00000172292 "Ceramide synthase 6" Q6ZMG9 2 168456249-168775134 "Metabolic proteins, Predicted membrane proteins" "Inflammatory response, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 271.7;Inhibitory neurons: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in many" 5 "dendritic cells: 5.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044683 Approved NA No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 9: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044683: AB_10965059" "unprognostic (2.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.92e-3)" "prognostic unfavorable (7.31e-4)" "unprognostic (3.24e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (9.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.93e-2)" "unprognostic (2.38e-1)" "unprognostic (1.14e-1)" "unprognostic (3.06e-2)" "unprognostic (2.41e-1)" "unprognostic (4.80e-2)" 13.4 14.3 10.1 10.1 11.6 12.5 13.5 11.8 17.4 12.7 2.4 28.2 25.8 11.6 18.1 13.7 6.7 8.5 27.6 12.9 14.4 13.2 13.3 7.6 8.6 4.1 7.4 15.3 7.6 12.3 4.7 9.4 7.9 12.9 30.2 9.2 3.6 13.3 6.0 19.1 32.2 11.0 9.0 6.9 24.1 12.0 8.8 24.9 27.2 10.7 8.3 12.6 6.9 8.1 15.8 14.2 24.2 27.8 58.8 43.2 0.1 15.5 16.1 16.7 22.2 22.2 33.8 0.0 21.7 14.1 23.3 28.9 32.2 36.6 27.6 0.0 21.4 29.1 13.8 15.9 51.5 61.1 13.4 48.7 102.1 34.7 27.3 16.0 8.5 42.2 15.8 0.1 34.6 17.2 54.0 16.9 22.4 33.6 20.0 41.3 45.5 27.3 15.5 46.9 32.6 39.4 15.0 38.2 8.2 19.9 34.0 34.4 4.7 41.3 17.3 11.3 27.1 0.3 0.0 0.1 26.8 31.8 28.2 0.6 1.0 0.0 0.1 0.7 0.3 0.1 0.3 0.1 0.8 0.4 0.9 0.7 0.1 0.7 0.6 5.4 0.0 0.3 10.1 11.6 11.8 17.4 12.9 14.4 4.1 7.4 7.9 9.0 8.8 8.1 7.0 6.4 10.3 114.3 10.2 108.8 55.2 37.4 38.1 24.1 42.4 30.6 45.1 21.5 33.6 11.0 0.0 0.7 45.2 79.1 0.0 14.0 6.8 7.9 20.3 13.4 103.8 15.3 271.7 22.5 3.4 11.3 57.6 18.9 10.2 15.2 12.8 43.8 24.3 37.0 293.2 92.2 20.3 49.4 54.1 3.6 19.9 40.8 10.6 37.5 77.8 28.1 6.2 124.7 10.3 17.9 48.3 39.9 9.8 40.3 63.7 9.3 49.2 3.0 65.7 13.4 28.8 3.0 9.4 34.9 92.8 0.5 10.1 15.7 115.8 46.3 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 SPC25 "AD024, MGC22228, SPBC25" ENSG00000152253 "SPC25 component of NDC80 kinetochore complex" Q9HBM1 2 168834132-168913371 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 23.5;Erythroid cells: 29.9;Extravillous trophoblasts: 37.9;Muller glia cells: 17.2;Spermatocytes: 26.2;Spermatogonia: 20.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047144, HPA050544" Enhanced Enhanced Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "HPA047144: AB_2679952, HPA050544: " "unprognostic (3.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.84e-2)" "prognostic unfavorable (4.74e-6)" "prognostic unfavorable (9.44e-5)" "unprognostic (1.84e-3)" "unprognostic (7.58e-2)" "unprognostic (1.36e-1)" "unprognostic (1.30e-2)" "unprognostic (1.11e-16)" "unprognostic (9.91e-3)" "unprognostic (1.85e-1)" "unprognostic (3.43e-1)" "unprognostic (1.57e-1)" 0.6 0.8 0.6 0.7 0.6 4.2 1.0 0.3 1.5 0.7 0.5 2.1 3.7 0.5 0.0 4.4 0.3 0.5 0.4 1.6 0.7 1.1 0.8 0.9 3.9 0.6 0.7 0.5 1.3 0.1 0.1 1.1 0.8 0.4 1.6 1.7 1.0 0.0 0.6 1.1 2.1 1.0 0.1 2.1 1.6 3.4 0.6 8.5 0.2 0.1 3.7 0.5 1.5 1.8 1.0 16.8 40.6 22.8 1.8 1.9 14.5 22.9 9.3 23.5 18.1 5.6 16.2 15.7 9.0 3.4 31.9 20.9 15.9 0.0 20.7 10.0 21.5 30.2 7.2 2.2 0.1 20.3 8.9 0.3 1.0 14.3 0.0 4.7 10.3 28.2 0.8 15.7 6.4 9.8 16.1 26.3 0.9 11.2 21.0 28.8 38.1 5.6 9.6 13.7 30.4 0.5 16.8 14.4 3.9 13.5 0.4 16.4 2.5 3.6 42.1 13.4 18.2 31.4 56.0 12.5 4.1 0.5 14.3 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.6 0.6 0.3 1.5 1.6 0.7 0.6 0.7 0.8 0.1 0.6 1.8 0.4 0.0 1.1 0.7 4.2 5.4 1.5 7.1 1.2 0.0 1.5 2.4 0.6 0.0 2.6 0.0 0.0 23.5 1.5 3.7 0.0 0.2 2.0 0.5 1.8 1.6 0.0 29.9 0.3 0.0 37.9 4.6 2.0 1.8 0.0 10.1 2.9 1.2 15.1 0.0 0.5 5.2 2.0 1.9 2.4 1.6 0.6 2.0 0.0 0.0 0.0 17.2 0.0 5.0 0.2 0.5 0.1 1.2 15.3 1.0 1.0 0.2 0.1 0.6 0.0 1.3 4.4 26.2 20.1 7.3 1.4 5.7 2.7 1.7 9.9 2.5 G6PC2 IGRP ENSG00000152254 "Glucose-6-phosphatase catalytic subunit 2" Q9NQR9 2 168901291-168910000 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Gluconeogenesis Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 38 "pancreas: 30.9;retina: 12.3" "Group enriched" "Detected in some" 13 "Early spermatids: 17.8;Muller glia cells: 53.0" "Cancer enriched" "Detected in single" 92 "pancreatic cancer: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (6.42e-2)" "unprognostic (2.39e-2)" "unprognostic (6.04e-2)" "unprognostic (9.05e-2)" "unprognostic (2.97e-1)" "unprognostic (3.10e-2)" "unprognostic (1.54e-2)" "unprognostic (1.87e-1)" 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.3 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.0 0.0 53.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 DHRS9 "3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4" ENSG00000073737 "Dehydrogenase/reductase 9" Q9BPW9 2 169064789-169096167 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.9;intestine: 70.4" "Cell type enhanced" "Detected in many" "Club cells: 229.3;Distal enterocytes: 261.2;Early spermatids: 153.2;Paneth cells: 299.9;Respiratory ciliated cells: 155.9;Syncytiotrophoblasts: 267.5;Urothelial cells: 249.2" "Cancer enhanced" "Detected in many" "pancreatic cancer: 16.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 258.3;eosinophil: 99.2;neutrophil: 77.3" "Lineage enriched" "Detected in many" 10 "granulocytes: 258.3" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 22.8;HUVEC TERT2: 21.5;NB-4: 33.7;THP-1: 98.0;TIME: 49.9;U-2197: 31.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036491, HPA036667" Approved "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA036491: AB_10673498, HPA036667: AB_10670237" "unprognostic (1.15e-1)" "unprognostic (3.82e-3)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (4.80e-2)" "unprognostic (2.35e-1)" "unprognostic (3.24e-2)" "unprognostic (1.40e-1)" "unprognostic (3.18e-1)" "unprognostic (3.62e-4)" "prognostic unfavorable (2.73e-4)" "unprognostic (2.72e-1)" "unprognostic (3.23e-1)" "unprognostic (1.85e-2)" "unprognostic (1.34e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-1)" 10.0 0.2 2.2 12.5 2.4 8.5 5.1 3.0 2.6 8.6 1.6 70.4 1.9 1.2 0.9 28.2 1.0 5.7 53.9 2.5 2.3 0.3 3.1 7.1 20.2 4.2 3.2 0.7 0.4 0.2 0.4 2.8 4.3 0.8 46.2 1.2 6.1 0.5 0.3 3.3 5.7 4.2 3.8 7.6 10.8 11.3 3.2 2.2 0.3 0.8 26.8 17.5 10.1 4.5 0.0 0.7 0.0 0.0 2.5 10.2 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.1 0.0 0.0 6.5 1.7 0.0 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 8.9 1.0 0.4 0.5 1.3 6.1 22.8 21.5 0.0 1.0 0.0 0.0 0.0 0.1 33.7 0.0 0.3 8.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 98.0 49.9 0.1 0.2 31.4 0.2 0.1 0.0 0.0 0.8 18.9 0.0 258.3 21.0 99.2 0.0 25.0 0.6 6.5 0.0 0.0 21.6 5.0 0.1 0.0 77.3 0.4 5.1 1.6 0.0 5.9 2.2 2.4 3.0 2.6 2.5 2.3 4.2 3.2 4.3 3.8 3.2 4.5 0.3 0.0 1.3 0.0 1.4 1.7 19.3 72.4 0.0 0.0 0.1 0.4 24.4 0.0 229.3 0.0 0.0 2.5 0.0 261.2 0.0 4.6 153.2 0.5 0.0 0.6 1.8 0.8 0.2 25.3 1.3 1.5 7.7 0.1 91.0 0.0 0.0 0.6 25.0 0.0 0.2 51.6 36.7 10.2 38.8 45.5 1.2 16.6 0.0 19.7 3.5 3.9 0.0 0.0 0.2 68.6 299.9 0.4 6.4 6.5 1.5 0.1 155.9 0.1 6.6 0.2 10.9 1.1 0.6 0.3 1.4 267.5 3.8 0.0 8.2 249.2 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 70.9;Early spermatids: 213.4;Endometrial ciliated cells: 49.1;Rod photoreceptor cells: 63.4;Spermatocytes: 62.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-MEL-30: 17.3" "Low region specificity" "Detected in all" HPA046125 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA046125: AB_2679549" "unprognostic (4.37e-2)" "unprognostic (5.48e-2)" "unprognostic (2.14e-1)" "unprognostic (1.89e-2)" "unprognostic (1.21e-2)" "unprognostic (4.85e-2)" "unprognostic (1.81e-1)" "unprognostic (5.83e-2)" "unprognostic (2.35e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.55e-1)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (1.67e-1)" 4.2 5.5 5.9 2.8 6.2 1.4 3.5 4.9 6.0 4.4 9.5 4.4 2.6 4.3 3.8 2.6 7.8 3.1 5.2 6.7 6.3 4.2 2.1 2.9 2.1 6.3 7.1 4.8 3.2 7.2 7.9 2.2 6.2 4.2 1.3 11.3 2.7 4.2 7.1 3.9 2.0 2.9 5.9 2.5 3.3 8.6 6.1 1.5 6.1 3.2 1.0 4.4 2.9 5.3 1.0 2.8 3.2 5.2 8.0 6.4 3.2 7.2 2.3 8.4 3.6 2.0 2.0 0.1 3.3 3.5 5.6 3.1 2.4 1.2 3.2 4.9 0.9 1.8 1.2 4.0 8.0 3.9 4.3 7.1 7.3 5.9 1.5 3.9 2.9 5.0 6.7 0.0 2.5 4.0 6.5 4.0 2.7 0.7 3.6 0.0 0.7 0.0 4.6 3.0 3.0 5.4 4.9 3.7 17.3 1.1 3.7 4.3 2.9 11.8 5.6 9.5 6.6 4.5 6.8 0.1 7.0 2.5 7.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.2 4.9 6.0 6.7 6.3 6.3 7.1 6.2 5.9 6.1 5.3 3.7 0.0 5.1 18.9 0.7 1.3 1.2 1.2 2.8 17.1 3.4 4.2 5.1 1.5 3.5 11.0 70.9 0.8 0.3 0.3 0.0 2.1 213.4 49.1 10.7 2.5 2.4 0.4 38.0 1.5 0.5 4.9 0.5 5.8 0.0 3.2 1.1 0.7 1.4 10.1 34.1 1.7 4.1 4.5 0.4 38.4 5.0 2.0 7.2 14.0 0.1 12.2 0.0 17.6 19.0 1.1 0.5 6.0 1.7 0.7 0.4 2.1 15.1 63.4 0.0 5.5 4.2 62.3 7.8 0.9 1.7 0.3 1.1 7.8 1.0 0.4 AC093899.2 ENSG00000251569 "Novel protein" 2 169479480-169525922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "retina: 18.5;testis: 8.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.6;HSkMC: 3.0;LHCN-M2: 5.4;SK-MEL-30: 2.5" HPA046125 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA046125: AB_2679549" 0.6 0.1 0.4 0.1 0.4 0.0 1.6 0.4 1.3 0.7 0.4 0.3 0.1 1.4 1.3 0.3 1.8 1.8 1.4 0.4 0.4 1.0 0.1 0.9 0.3 0.5 0.5 1.2 0.4 1.0 0.5 0.4 0.5 1.7 0.7 18.5 0.4 1.3 2.6 0.2 0.1 1.0 0.4 0.6 0.4 8.8 0.4 0.6 1.8 2.4 0.6 0.8 0.1 0.4 0.0 0.0 1.0 0.1 0.8 4.6 0.0 1.0 0.6 0.9 0.5 0.0 0.0 0.0 0.2 1.1 1.2 0.0 0.7 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.1 0.5 0.0 3.0 0.5 1.2 0.4 1.1 1.5 0.9 0.3 0.0 5.4 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.7 0.1 0.3 0.0 2.5 0.1 0.2 0.0 0.0 0.7 0.2 0.0 0.2 0.0 0.5 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.4 0.4 0.5 0.5 0.5 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 5038.6;tongue: 3473.7" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 108.1;Skeletal myocytes: 251.8" "Group enriched" "Detected in some" 9 "head and neck cancer: 10.8;prostate cancer: 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HSkMC: 21.6;LHCN-M2: 35.4;RH-30: 55.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: AB_1852087, HPA021753: AB_1852089, HPA021760: AB_1852091" "unprognostic (2.44e-2)" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (2.94e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" "unprognostic (2.05e-1)" "unprognostic (5.46e-3)" "unprognostic (1.88e-1)" "unprognostic (5.38e-2)" "unprognostic (6.65e-4)" "unprognostic (9.64e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (1.52e-1)" 1.5 0.5 1.7 0.2 1.4 0.0 2.0 3.1 1.8 1.0 1.4 1.4 0.1 0.8 1.5 75.1 1.2 6.7 100.3 1.2 1.6 0.8 0.9 2.7 0.3 0.9 2.5 1.1 1.1 0.5 5.8 0.1 1.5 50.0 0.3 16.1 52.1 0.7 5038.6 4.6 0.8 0.6 0.9 0.8 1.3 2.6 5.1 1.7 2.2 3473.7 0.3 5.9 0.9 1.4 0.0 0.1 0.0 0.6 0.4 2.7 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.2 0.2 0.0 21.6 0.5 0.3 0.0 0.2 0.1 0.2 0.1 0.0 35.4 0.1 0.1 0.2 0.0 0.0 0.2 0.0 55.9 0.0 0.2 0.1 0.7 0.1 0.1 0.0 1.5 0.1 0.0 0.1 0.0 0.4 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 3.1 1.8 1.2 1.6 0.9 2.5 1.5 0.9 5.1 1.4 0.0 0.0 0.5 1.3 0.0 0.1 0.5 0.1 0.0 2.4 0.2 0.1 108.1 0.0 2.0 0.0 8.4 0.0 0.0 0.1 0.0 0.5 5.8 1.3 0.2 1.0 1.2 0.0 4.1 0.5 0.0 6.4 0.0 0.1 0.0 0.2 0.4 0.2 0.2 0.0 4.6 0.1 0.0 0.3 0.0 2.9 0.9 0.8 0.0 3.7 0.0 0.7 0.0 1.5 2.3 0.7 0.1 1.2 0.0 0.3 0.0 0.3 4.1 5.8 0.0 251.8 1.8 4.1 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.1 FASTKD1 FLJ21901 ENSG00000138399 "FAST kinase domains 1" Q53R41 2 169528508-169573875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.8;Inhibitory neurons: 89.9;Oligodendrocyte precursor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043719 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043719: AB_2678635" "unprognostic (3.08e-3)" "unprognostic (1.63e-1)" "unprognostic (6.91e-3)" "unprognostic (8.03e-3)" "unprognostic (1.99e-2)" "unprognostic (3.84e-1)" "unprognostic (5.56e-3)" "unprognostic (1.15e-1)" "unprognostic (3.83e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (2.17e-1)" "unprognostic (4.26e-3)" "unprognostic (2.23e-2)" "unprognostic (1.41e-1)" "unprognostic (7.58e-2)" "unprognostic (7.62e-3)" 6.0 7.8 8.2 10.0 9.2 7.1 7.7 15.2 12.6 4.4 20.5 17.5 17.8 6.4 10.5 11.9 5.3 5.3 27.2 8.6 8.4 10.8 10.1 6.5 10.2 10.0 7.6 2.5 8.7 15.4 8.2 8.3 10.4 5.6 22.1 17.8 9.8 6.3 15.4 7.3 16.8 9.0 7.5 8.9 9.7 10.5 7.0 10.0 10.8 26.4 12.4 9.1 6.5 11.3 10.9 12.2 15.6 18.1 10.4 14.6 27.0 18.2 10.5 14.4 17.5 19.4 17.5 33.6 16.8 11.4 25.0 29.4 43.9 19.8 23.2 30.7 23.6 48.6 18.8 22.7 7.9 45.7 14.7 10.0 17.3 21.9 12.5 12.0 20.9 28.7 36.0 18.6 18.9 7.8 35.9 37.5 30.9 30.6 14.9 28.2 17.1 40.8 21.2 18.4 34.3 11.2 16.4 30.9 26.8 26.9 5.7 42.7 14.1 16.8 16.8 16.7 18.7 16.5 34.3 24.8 14.3 39.5 11.6 20.6 4.7 2.2 3.3 5.5 4.7 4.9 4.4 3.7 6.3 4.3 4.7 4.0 0.5 7.1 2.6 6.2 3.1 2.5 8.2 9.2 15.2 12.6 8.6 8.4 10.0 7.6 10.4 7.5 7.0 11.3 5.2 16.0 8.7 46.0 12.7 5.4 6.4 9.8 13.1 16.5 5.7 4.3 30.4 10.0 9.2 3.7 25.0 10.1 10.6 18.3 1.9 6.1 13.4 6.9 8.8 6.6 15.0 21.7 91.8 4.8 10.2 4.7 13.3 7.2 18.3 10.2 5.7 8.0 13.1 11.8 89.9 12.1 10.2 10.0 4.2 5.1 0.9 11.3 1.8 36.5 10.6 3.7 5.2 64.8 46.3 5.8 13.1 2.6 52.9 5.6 16.7 7.4 5.4 19.4 0.0 7.3 3.9 27.2 6.5 19.4 4.4 8.1 9.6 9.0 17.2 7.7 PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" Cytosol "HPA021788: AB_1847408, HPA057469: AB_2683445" "unprognostic (2.70e-1)" "unprognostic (2.17e-1)" "unprognostic (2.40e-1)" "unprognostic (2.04e-3)" "unprognostic (4.17e-2)" "unprognostic (3.49e-2)" "unprognostic (1.55e-3)" "unprognostic (3.66e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-3)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (4.56e-4)" "unprognostic (5.23e-2)" "unprognostic (3.29e-1)" "unprognostic (3.41e-2)" "unprognostic (3.39e-2)" 26.0 23.2 23.1 28.4 22.1 54.2 27.5 28.8 58.6 27.6 22.9 26.3 26.6 28.8 31.5 27.5 23.6 22.0 25.6 21.5 29.9 29.2 47.1 24.7 36.9 24.6 25.6 26.5 21.2 32.6 25.8 28.0 24.3 27.9 26.0 29.3 26.5 22.9 27.6 25.4 29.7 21.7 22.9 32.3 27.4 20.1 23.7 36.1 29.9 26.2 35.4 26.3 26.5 25.9 56.4 25.5 70.8 35.9 35.4 42.5 63.7 58.9 42.3 45.0 45.9 66.3 58.9 94.8 52.5 44.1 55.5 50.5 56.6 48.4 65.6 68.0 45.7 129.9 36.7 88.3 34.4 136.8 58.9 36.6 54.0 58.5 64.6 40.6 50.4 53.5 142.7 76.2 49.5 43.5 101.0 81.9 100.8 45.3 25.1 90.7 71.7 90.5 53.9 81.2 60.5 41.2 63.4 47.2 68.9 52.9 44.2 78.7 52.7 53.9 43.7 38.4 52.6 41.1 65.3 126.8 38.5 68.1 54.1 31.9 22.5 36.7 22.8 25.1 26.7 32.9 30.9 29.2 18.2 38.4 33.4 27.6 40.4 21.1 31.4 30.0 26.8 17.0 23.1 22.1 28.8 58.6 21.5 29.9 24.6 25.6 24.3 22.9 23.7 25.9 159.7 221.2 175.1 53.5 188.8 151.4 191.4 185.9 101.3 204.6 120.8 156.1 148.4 107.2 169.5 93.8 54.2 170.0 160.1 91.6 80.3 103.1 11.0 104.6 142.3 141.1 104.8 163.5 82.4 103.3 177.0 142.4 66.8 126.3 179.1 115.8 121.7 181.2 151.7 220.4 81.8 135.8 116.0 130.3 126.5 15.6 142.0 129.6 110.3 46.9 152.4 137.6 133.9 53.8 69.7 93.9 118.0 146.7 130.1 161.8 121.1 113.8 132.2 109.1 164.3 150.2 193.9 276.4 183.8 108.3 172.8 205.5 166.7 147.1 149.9 167.7 CCDC173 "C2orf77, LOC129881" ENSG00000154479 "Coiled-coil domain containing 173" Q0VFZ6 2 169645425-169694405 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 22.2;testis: 80.2" "Cell type enhanced" "Detected in many" "Early spermatids: 939.2;Endometrial ciliated cells: 118.1;Late spermatids: 133.4;Respiratory ciliated cells: 232.6;Spermatocytes: 460.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HEL: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042995, HPA048454" Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA042995: AB_2678260, HPA048454: AB_2680400" "unprognostic (1.66e-2)" "unprognostic (2.68e-2)" "unprognostic (2.27e-1)" "unprognostic (3.16e-2)" "unprognostic (9.20e-2)" "unprognostic (4.18e-2)" "unprognostic (3.56e-3)" "unprognostic (3.05e-1)" "unprognostic (3.14e-2)" "unprognostic (1.69e-1)" "unprognostic (5.26e-6)" "unprognostic (8.73e-2)" "unprognostic (1.20e-1)" "unprognostic (2.20e-2)" "unprognostic (5.80e-2)" "unprognostic (1.49e-2)" "unprognostic (1.41e-1)" 0.3 0.3 7.4 0.7 7.8 3.6 1.3 4.4 11.6 1.0 22.2 0.2 0.6 1.2 1.1 0.2 14.9 0.5 0.1 8.7 7.1 0.9 0.4 2.5 0.2 13.7 16.6 0.8 1.4 1.6 2.6 0.1 9.6 0.4 0.4 6.7 0.2 0.8 0.1 0.2 0.4 0.6 11.3 0.1 0.4 80.2 8.1 0.2 3.4 0.0 0.0 0.2 0.2 9.6 0.5 0.8 0.8 0.2 0.0 0.1 0.9 0.4 0.0 0.4 0.1 0.3 0.1 0.1 0.1 0.0 0.7 0.6 0.7 1.0 0.7 0.1 0.5 11.1 0.7 0.3 0.0 1.1 2.5 0.0 0.1 1.4 0.0 0.6 0.0 0.6 2.5 0.1 0.0 1.2 0.2 0.3 0.2 0.3 0.6 0.0 0.0 0.0 0.3 0.5 2.7 0.7 0.1 0.0 0.0 0.3 0.6 0.1 0.0 0.2 0.1 0.7 0.4 0.4 0.3 0.3 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.4 7.8 4.4 11.6 8.7 7.1 13.7 16.6 9.6 11.3 8.1 9.6 1.5 9.6 8.3 12.7 1.6 0.1 2.5 3.8 1.2 13.3 2.2 3.9 0.6 0.0 31.7 1.8 8.4 0.2 4.1 0.1 5.9 0.4 939.2 118.1 3.3 1.2 0.0 0.0 5.8 0.4 2.6 3.5 1.5 2.3 2.5 0.5 1.4 0.8 0.0 0.0 2.3 0.7 8.2 0.3 0.2 133.4 7.5 1.0 1.8 2.8 0.0 7.3 0.0 1.5 0.5 0.1 0.0 6.8 1.9 0.5 0.0 3.2 232.6 13.7 13.1 21.2 1.8 460.3 13.7 0.0 0.0 0.1 3.3 0.1 0.1 0.9 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 158.7;Spermatocytes: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA034726: AB_10602191, HPA034727: AB_2674302" "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favorable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 5.0 2.8 1.9 2.4 1.9 2.9 10.6 4.1 1.6 4.7 3.7 5.8 6.4 5.3 4.2 3.2 6.0 4.0 2.7 1.6 2.8 5.6 3.6 3.3 3.0 1.4 1.8 6.0 5.1 7.2 4.6 3.0 1.5 13.0 5.8 7.2 8.5 4.7 3.4 3.5 6.4 3.1 1.7 2.5 4.7 13.7 2.4 3.0 9.8 1.6 3.0 3.8 2.8 1.9 6.6 1.8 4.6 6.2 8.5 2.7 17.8 2.8 1.9 4.3 4.7 6.3 4.9 6.4 6.1 2.1 8.9 5.0 6.2 3.4 3.5 9.5 7.0 6.4 6.1 11.0 5.6 5.3 5.6 4.9 6.3 4.9 6.5 3.6 3.9 8.9 10.8 6.4 2.7 6.0 3.7 6.8 6.0 4.2 2.3 3.6 2.8 5.1 6.8 19.6 19.1 6.5 5.8 3.1 6.8 5.5 8.4 3.2 2.3 4.7 4.3 4.2 3.1 6.2 6.0 5.7 5.5 3.2 5.1 0.1 0.7 1.0 3.3 0.9 4.6 6.5 3.6 3.2 0.9 8.8 4.7 4.6 1.3 9.8 0.9 4.2 4.4 1.4 1.9 1.9 4.1 1.6 1.6 2.8 1.4 1.8 1.5 1.7 2.4 1.9 6.1 3.2 3.6 0.0 6.8 2.5 10.3 5.4 2.8 8.7 15.2 11.0 4.1 5.7 4.7 3.7 6.2 8.8 2.5 7.0 9.8 7.6 158.7 10.6 5.0 4.3 15.0 6.9 0.0 11.1 9.3 6.9 15.3 3.3 0.0 5.7 2.5 3.7 2.8 6.7 0.0 6.6 12.2 0.6 1.6 35.9 4.7 2.0 3.6 0.0 1.0 6.4 1.0 0.0 0.0 6.4 6.8 4.9 3.8 6.5 12.7 12.2 13.4 10.2 0.0 6.7 9.3 68.9 13.9 4.5 4.3 5.5 5.7 8.8 7.5 5.5 KLHL23 "FLJ37812, MGC22679, MGC2610" ENSG00000213160 "Kelch like family member 23" Q8NBE8 2 169694488-169776989 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 132.5;Cone photoreceptor cells: 89.6;Sertoli cells: 170.9;Smooth muscle cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SCLC-21H: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047593 Approved "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Actin filaments" "HPA047593: " "unprognostic (4.77e-2)" "unprognostic (2.65e-2)" "unprognostic (7.48e-2)" "unprognostic (4.12e-3)" "unprognostic (1.66e-2)" "unprognostic (2.13e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (4.19e-2)" "unprognostic (3.64e-3)" "unprognostic (1.05e-2)" "unprognostic (4.09e-1)" "unprognostic (4.21e-2)" "prognostic unfavorable (2.43e-5)" "unprognostic (2.61e-1)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (4.87e-3)" 6.9 2.1 8.1 6.1 9.6 1.7 6.2 13.2 9.9 9.6 0.2 20.8 11.1 25.6 4.0 12.0 8.9 6.7 8.0 9.8 7.2 6.6 5.9 5.9 3.1 3.7 5.8 17.9 7.2 6.4 3.3 12.8 4.6 13.6 13.9 13.6 8.0 12.5 12.0 1.6 11.8 25.0 4.0 2.8 5.1 10.9 7.6 11.1 8.1 16.3 2.9 8.7 3.9 6.3 17.0 8.6 64.5 18.3 3.6 1.3 43.7 8.0 6.1 14.4 15.8 18.0 14.4 10.6 6.7 0.8 20.9 2.6 67.7 5.8 21.9 37.7 33.2 31.3 16.9 29.9 5.4 44.2 4.7 2.5 4.7 6.0 10.2 9.3 11.2 38.3 43.5 1.4 4.8 8.2 65.0 17.9 52.7 9.0 6.7 20.7 55.1 1.1 13.1 49.9 83.4 57.1 12.7 1.2 7.8 20.3 10.6 14.2 4.2 5.8 18.6 5.7 13.6 4.9 4.9 47.3 4.5 13.0 9.0 0.0 0.0 0.0 0.7 0.0 0.9 0.3 0.6 0.5 0.1 0.3 1.0 1.0 0.0 3.4 0.0 0.9 0.8 0.3 8.1 9.6 13.2 9.9 9.8 7.2 3.7 5.8 4.6 4.0 7.6 6.3 13.7 3.2 8.7 0.0 1.1 1.5 6.9 2.8 7.4 132.5 15.0 17.1 52.9 14.3 6.7 0.0 89.6 5.6 3.8 14.6 3.9 15.6 4.6 2.4 12.8 12.6 31.8 9.7 0.0 30.5 9.6 11.2 4.1 5.5 0.0 27.5 7.5 11.8 0.9 40.4 0.0 21.2 28.5 0.8 1.9 3.7 2.5 1.3 0.0 0.0 0.2 14.6 5.2 0.0 0.0 16.1 13.6 8.6 0.4 17.2 9.7 16.9 4.9 34.8 170.9 11.4 102.6 3.4 20.9 4.7 1.0 1.2 5.5 13.8 20.9 4.1 SSB "La, La/SSB, LARP3" ENSG00000138385 "Small RNA binding exonuclease protection factor La" P05455 2 169791933-169812064 "Predicted intracellular proteins" RNA-binding "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004643, HPA017287" Supported Approved Nucleoplasm NA NA 93000 "Cluster 42: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "CAB004643: AB_425691, HPA017287: AB_1852672" "unprognostic (5.58e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (9.05e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.99e-4)" "prognostic unfavorable (8.30e-8)" "unprognostic (1.09e-2)" "unprognostic (1.45e-2)" "unprognostic (9.81e-3)" "unprognostic (3.24e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (6.17e-6)" "unprognostic (9.92e-2)" "unprognostic (2.43e-1)" "unprognostic (1.21e-3)" "unprognostic (2.38e-2)" 114.1 75.6 53.7 75.8 54.9 105.3 76.0 55.5 72.8 59.3 63.3 61.7 49.2 68.6 82.0 51.6 61.0 58.1 69.0 53.8 58.0 74.5 68.5 55.9 93.3 55.5 58.3 68.9 40.2 80.0 64.6 73.6 55.6 78.2 57.1 55.2 49.9 58.8 62.3 46.6 49.3 61.5 55.3 62.7 49.8 41.1 55.2 70.2 81.7 52.9 81.2 88.4 51.2 55.2 189.0 109.3 231.2 173.5 244.9 226.0 287.8 226.8 150.8 208.2 192.7 332.9 201.7 419.8 251.7 149.8 188.9 197.9 315.3 198.6 283.9 231.2 258.4 505.9 138.0 323.4 218.6 410.8 181.5 175.1 187.1 265.0 156.8 170.6 235.4 156.1 599.0 95.5 442.4 149.5 273.6 428.2 373.3 180.7 110.5 267.9 245.7 304.6 266.3 205.6 219.8 168.0 179.9 132.4 262.9 223.4 152.5 292.0 213.9 151.1 180.1 153.8 221.9 110.3 227.3 355.9 149.2 381.4 168.2 83.4 47.3 59.9 71.9 81.6 104.2 89.8 100.9 92.1 56.8 75.8 90.5 97.0 7.9 93.8 104.5 60.6 100.9 67.2 53.7 54.9 55.5 72.8 53.8 58.0 55.5 58.3 55.6 55.3 55.2 55.2 143.0 86.6 79.9 21.9 107.9 91.6 229.2 308.7 83.6 114.7 78.1 126.7 91.9 77.2 168.9 112.2 27.1 212.4 111.6 33.6 187.9 206.6 20.3 235.3 188.4 131.5 73.0 154.2 25.4 146.7 212.4 133.5 46.9 101.2 205.0 111.4 92.8 77.0 185.7 136.3 26.8 82.7 240.1 86.8 91.4 49.7 184.2 111.7 80.0 15.0 113.4 152.7 84.5 20.1 21.5 113.2 47.8 186.9 78.7 199.2 40.2 194.9 371.1 91.4 216.9 183.7 194.8 154.4 156.7 68.5 88.4 165.4 128.4 183.3 100.0 155.9 METTL5 HSPC133 ENSG00000138382 "Methyltransferase like 5" Q9NRN9 2 169810081-169824931 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038223 Uncertain Approved Nucleoli,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Cytosol "HPA038223: AB_10672509" "unprognostic (2.55e-2)" "unprognostic (8.41e-2)" "unprognostic (4.73e-1)" "unprognostic (3.94e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (6.64e-5)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-2)" "unprognostic (2.15e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (3.06e-8)" "unprognostic (8.53e-2)" "unprognostic (1.70e-1)" "unprognostic (1.95e-2)" "unprognostic (6.87e-3)" 51.1 39.5 41.3 27.7 42.5 34.0 50.2 41.0 57.0 30.4 36.1 53.7 29.4 29.4 63.0 36.6 29.2 25.1 65.5 41.9 45.2 38.5 46.9 24.1 35.4 41.0 42.5 25.7 54.1 36.7 30.2 30.7 42.4 32.5 42.2 30.5 47.1 32.1 92.9 32.7 33.0 36.6 43.7 26.4 43.0 24.3 45.1 30.8 37.7 73.5 38.4 42.3 31.5 45.0 97.1 52.5 74.6 83.1 66.9 99.6 122.6 80.1 74.8 95.4 76.1 164.2 111.2 122.8 95.0 66.0 126.8 98.5 103.0 167.9 133.3 95.3 73.8 185.8 40.6 181.8 90.9 235.9 87.6 73.6 220.2 121.2 147.7 99.4 90.0 165.8 176.0 99.9 123.1 93.8 113.7 190.5 101.4 125.5 98.5 113.7 70.0 190.6 167.0 87.5 90.5 67.6 51.5 80.2 146.0 84.2 75.7 104.6 62.2 103.4 84.5 65.4 104.3 97.0 158.8 206.3 86.3 113.7 95.3 45.5 26.0 21.1 39.9 32.5 61.5 65.0 54.8 53.9 32.0 56.3 56.5 52.3 7.7 45.3 31.8 49.5 57.8 34.8 41.3 42.5 41.0 57.0 41.9 45.2 41.0 42.5 42.4 43.7 45.1 45.0 67.1 12.8 28.8 6.8 49.1 38.6 88.9 105.2 47.8 24.8 64.0 111.4 83.1 50.1 65.4 44.1 16.7 96.1 43.2 36.1 111.6 115.6 3.9 61.0 34.8 48.6 60.6 70.9 10.8 146.2 117.4 43.8 24.5 43.1 46.3 35.1 46.4 49.5 77.2 23.5 11.0 66.7 59.0 36.9 33.3 8.7 50.4 35.9 55.2 9.4 53.7 51.6 53.5 7.1 13.2 149.7 48.8 60.2 48.1 92.5 72.2 115.8 61.3 23.0 52.6 47.2 66.5 49.2 97.4 56.2 40.9 39.1 47.6 48.4 69.3 89.2 UBR3 "DKFZp434P117, FLJ37422, KIAA2024, ZNF650" ENSG00000144357 "Ubiquitin protein ligase E3 component n-recognin 3" Q6ZT12 2 169827454-170084131 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 71.2;tongue: 87.1" "Cell type enhanced" "Detected in all" "Astrocytes: 162.6;Excitatory neurons: 305.1;Inhibitory neurons: 302.0;Oligodendrocyte precursor cells: 232.2;Oligodendrocytes: 288.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035390 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "HPA035390: AB_10670699" "unprognostic (1.35e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-2)" "unprognostic (1.27e-1)" "unprognostic (2.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.00e-1)" "unprognostic (3.91e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.26e-1)" "unprognostic (3.19e-2)" "unprognostic (5.56e-2)" "unprognostic (2.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.18e-1)" 14.2 12.4 4.4 7.7 5.8 7.4 9.2 5.9 8.5 10.9 2.8 8.8 8.1 10.1 6.9 12.8 8.4 9.3 29.4 8.0 3.3 15.2 21.0 8.8 7.2 2.4 2.7 10.2 11.9 21.5 2.1 8.7 3.3 13.1 8.5 21.2 11.5 10.3 71.2 9.2 7.5 11.1 3.2 8.8 9.3 9.7 3.4 9.5 17.9 87.1 7.3 11.0 2.3 8.4 14.8 12.4 12.9 17.1 25.0 19.7 10.8 26.1 15.0 14.7 11.8 19.1 9.1 16.7 22.2 20.5 12.0 19.0 15.5 13.2 18.2 17.4 13.4 61.1 12.6 20.3 12.4 20.4 18.9 11.9 12.1 19.3 12.9 11.7 14.8 8.3 32.4 17.6 25.6 14.0 13.3 10.0 10.1 14.9 10.2 12.6 21.1 17.8 10.5 20.5 25.1 13.7 18.4 16.7 10.6 10.2 10.9 11.4 18.9 22.1 9.0 17.5 16.7 14.2 11.9 15.1 18.2 11.8 12.5 0.0 0.6 0.5 0.9 0.6 1.3 0.6 0.5 0.8 0.9 0.3 0.9 1.2 0.6 0.8 0.5 0.7 1.0 0.4 4.4 5.8 5.9 8.5 8.0 3.3 2.4 2.7 3.3 3.2 3.4 8.4 19.0 44.8 26.9 162.6 16.3 25.9 12.4 14.8 20.5 46.3 15.8 8.9 109.7 17.2 20.0 12.9 81.3 19.7 22.9 17.1 3.9 8.7 7.6 16.8 21.9 26.4 16.7 24.4 305.1 11.0 8.4 22.2 23.4 22.0 16.5 22.7 30.4 39.0 10.2 63.9 302.0 11.3 22.4 20.9 18.7 10.2 25.7 18.7 16.0 110.5 18.7 61.7 14.4 232.2 288.0 10.7 15.0 19.2 21.3 20.9 15.3 10.0 13.4 51.5 26.3 29.0 21.8 12.4 8.6 22.9 29.0 23.0 18.1 17.3 13.2 17.2 MYO3B ENSG00000071909 "Myosin IIIB" Q8WXR4 2 170178145-170655171 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 14.1;kidney: 5.3;parathyroid gland: 8.8;retina: 5.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 85.5;Early spermatids: 34.2;Inhibitory neurons: 18.3;Late spermatids: 29.6;Rod photoreceptor cells: 51.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 11.2;HEL: 8.8;RT4: 11.7" "Region enriched" "Detected in some" 5 "basal ganglia: 5.2" "Not detected" "Not detected" HPA045483 Approved NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA045483: AB_2679344" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.96e-2)" "unprognostic (1.43e-2)" "unprognostic (1.67e-1)" "unprognostic (7.15e-3)" "unprognostic (5.07e-2)" "unprognostic (2.61e-2)" "unprognostic (5.84e-3)" "unprognostic (2.12e-1)" "unprognostic (7.99e-3)" "unprognostic (2.59e-1)" "unprognostic (4.25e-5)" "unprognostic (2.34e-1)" "unprognostic (8.12e-3)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 14.1 0.4 0.6 0.1 0.0 0.0 0.3 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 8.8 0.3 0.0 0.0 0.0 0.0 5.8 0.1 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.4 1.3 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 11.2 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.1 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.3 0.3 0.6 0.5 0.3 0.0 3.1 0.2 0.3 0.7 0.0 0.5 3.7 85.5 0.0 0.6 0.1 13.7 0.3 34.2 5.3 0.4 0.3 1.8 0.0 1.8 0.0 0.0 0.8 0.0 1.7 0.0 0.1 0.0 0.2 0.0 0.0 18.3 0.6 0.0 0.3 1.1 29.6 0.3 0.2 0.0 1.9 0.0 3.0 0.0 5.5 2.9 0.1 0.0 0.4 0.0 0.2 0.0 0.2 0.2 51.0 0.0 1.7 0.5 1.5 0.8 0.3 0.4 0.1 0.3 0.3 0.0 0.1 SP5 ENSG00000204335 "Sp5 transcription factor" Q6BEB4 2 170715337-170718078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 8.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.8;Cardiomyocytes: 3.1;Distal tubular cells: 3.9;Endometrial stromal cells: 7.1;Fibroblasts: 4.4;Intestinal goblet cells: 4.3;Spermatogonia: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 122.1" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Low region specificity" "Detected in some" HPA074123 Approved Nucleoplasm,Nucleoli NA NA "Cluster 31: Skin - Epidermis development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Nucleoli Nucleoplasm "HPA074123: AB_2686664" "unprognostic (1.16e-2)" "unprognostic (6.99e-2)" "unprognostic (3.41e-2)" "unprognostic (2.10e-2)" "unprognostic (1.14e-1)" "unprognostic (9.52e-3)" "unprognostic (1.45e-1)" "unprognostic (4.60e-2)" "unprognostic (4.77e-1)" "unprognostic (8.97e-3)" "unprognostic (1.79e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-8)" "unprognostic (8.05e-3)" "unprognostic (2.49e-1)" "unprognostic (2.41e-2)" "unprognostic (2.17e-1)" 2.5 1.2 0.5 0.2 0.5 0.0 1.4 2.2 0.3 8.8 0.5 1.5 1.0 3.7 0.4 1.2 1.2 0.2 0.2 0.2 1.4 0.2 2.1 0.5 0.2 0.3 1.4 0.4 0.4 0.3 0.1 0.2 0.2 1.7 0.2 0.0 1.5 0.2 0.2 4.6 1.4 0.1 0.0 0.0 3.1 0.8 1.8 0.1 0.1 0.0 0.8 1.5 2.2 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 27.7 0.1 0.0 0.5 0.0 0.5 1.5 0.3 0.0 0.0 3.5 0.3 0.4 0.1 122.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 2.0 2.3 0.0 0.0 0.0 0.1 0.0 0.1 0.3 4.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 2.2 0.3 0.2 1.4 0.3 1.4 0.2 0.0 1.8 0.2 0.2 0.0 0.0 0.3 0.0 0.8 0.1 0.0 2.8 0.0 0.2 0.3 3.1 0.0 0.0 1.8 0.0 1.5 0.1 0.3 3.9 0.0 0.2 2.3 7.1 0.5 0.0 0.0 0.0 0.0 0.0 4.4 0.0 1.3 0.0 0.0 0.0 2.5 0.2 0.0 0.4 4.3 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.4 0.4 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.7 0.2 0.1 0.3 0.2 0.0 1.6 0.0 ERICH2 ENSG00000204334 "Glutamate rich 2" A1L162 2 170783786-170798971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 163.9" "Cell type enriched" "Detected in many" 7 "Early spermatids: 2216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "hTCEpi: 61.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 33.1" HPA061010 Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli fibrillar center" Vesicles "HPA061010: " "unprognostic (1.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.26e-1)" "prognostic favorable (9.49e-4)" "unprognostic (7.57e-3)" "unprognostic (6.61e-2)" "unprognostic (9.62e-3)" "unprognostic (6.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-2)" "unprognostic (1.12e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (8.98e-7)" "unprognostic (1.03e-1)" "unprognostic (5.28e-3)" "unprognostic (7.35e-2)" "unprognostic (2.76e-1)" 1.4 1.8 5.8 0.2 6.3 0.0 4.3 6.0 7.3 6.2 15.0 0.8 0.1 4.9 3.6 0.6 9.5 1.8 3.9 5.4 7.0 3.5 5.4 12.1 0.3 5.2 5.7 2.2 2.9 7.9 1.4 0.4 5.3 2.2 0.7 6.9 2.5 2.2 1.1 0.6 0.3 1.3 5.0 0.1 3.9 163.9 5.7 0.3 18.6 3.5 0.6 1.1 0.9 5.3 9.5 0.0 0.1 7.7 0.0 0.0 0.4 0.0 0.0 1.5 3.1 7.9 1.9 0.0 0.3 0.0 3.4 0.2 2.0 0.7 0.1 1.3 2.0 4.1 0.0 0.1 7.8 0.4 0.5 1.2 61.5 0.0 14.1 0.2 0.0 1.5 9.2 0.0 0.0 3.3 0.0 0.8 9.5 11.3 1.6 0.0 1.5 0.0 4.4 0.2 1.1 2.0 5.6 0.1 2.4 1.8 1.3 1.3 0.0 2.0 1.7 0.0 0.9 0.0 0.0 0.0 7.7 3.8 6.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.3 6.0 7.3 5.4 7.0 5.2 5.7 5.3 5.0 5.7 5.3 0.2 6.4 24.4 8.1 0.1 0.3 0.6 1.7 0.0 1.6 1.0 2.0 2.0 2.8 2.3 1.8 0.0 0.0 0.0 0.1 13.7 0.9 2216.6 25.7 3.6 0.9 7.7 0.0 4.4 1.8 0.2 1.0 0.0 1.3 0.0 0.7 0.0 2.5 0.0 0.0 12.7 1.6 2.0 0.0 0.0 302.9 9.6 0.9 0.0 1.9 0.0 2.0 0.0 6.6 4.0 1.3 0.0 7.5 0.0 0.2 0.0 0.7 21.5 0.5 6.6 0.8 1.0 39.1 10.8 0.0 0.1 0.0 0.1 0.2 0.4 0.1 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 8 "Inhibitory neurons: 392.8;Oligodendrocyte precursor cells: 146.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 20.1;HEL: 64.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 0.2 3.0 22.1 0.0 29.9 3.3 0.1 15.5 33.0 1.0 0.0 0.0 0.0 1.6 4.3 0.4 0.2 0.1 0.0 17.1 98.5 4.8 0.1 0.2 0.1 12.4 41.6 0.2 0.2 46.3 5.0 0.4 17.6 0.8 0.1 29.7 0.1 0.3 0.0 0.2 0.1 0.0 12.7 0.1 0.0 3.2 31.1 0.8 0.1 0.0 0.2 0.6 0.4 14.2 18.2 0.7 0.0 7.3 0.0 0.0 0.1 0.4 0.0 2.6 1.7 4.6 6.7 0.0 0.9 0.5 2.9 20.1 2.3 0.6 1.6 2.8 13.4 64.5 6.0 0.2 0.0 0.3 1.1 0.0 5.5 0.0 2.3 0.6 0.1 0.5 17.0 0.3 0.8 1.5 0.0 0.0 8.1 9.7 6.7 1.0 4.6 0.4 8.5 9.4 6.7 2.1 12.6 0.0 3.5 0.6 0.2 0.0 0.0 12.0 1.7 2.4 7.0 0.0 0.0 0.1 11.5 3.2 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 29.9 15.5 33.0 17.1 98.5 12.4 41.6 17.6 12.7 31.1 14.2 0.0 0.0 0.0 14.7 0.0 0.3 2.1 7.7 2.2 32.5 0.1 0.1 1.3 0.0 3.6 0.0 10.4 0.0 0.0 0.2 7.9 4.5 5.6 4.4 0.4 0.4 3.0 5.5 2.6 5.6 0.1 0.2 0.0 2.9 0.0 5.5 0.0 0.0 4.0 5.0 392.8 0.3 2.0 0.8 0.4 6.2 0.6 0.5 0.0 7.5 0.0 4.9 0.0 146.8 7.6 2.9 0.0 0.0 0.1 0.9 0.0 0.0 4.7 6.0 0.0 0.0 1.2 4.4 7.7 0.6 0.1 0.5 0.0 0.1 0.1 0.4 GORASP2 "GOLPH6, GRASP55, GRS2" ENSG00000115806 "Golgi reassembly stacking protein 2" Q9H8Y8 2 170928464-170967130 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 380.7;Syncytiotrophoblasts: 229.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035274, HPA035275, CAB075758" Enhanced Enhanced "Golgi apparatus" NA NA 830000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "CAB075758: AB_2665764, HPA035274: AB_2674546, HPA035275: AB_10602600" "unprognostic (2.04e-2)" "unprognostic (4.37e-3)" "unprognostic (4.61e-1)" "unprognostic (1.64e-1)" "unprognostic (9.94e-2)" "prognostic unfavorable (7.32e-4)" "unprognostic (3.13e-2)" "unprognostic (3.13e-1)" "unprognostic (1.36e-1)" "unprognostic (1.58e-1)" "unprognostic (4.56e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.38e-8)" "unprognostic (1.26e-1)" "unprognostic (2.13e-1)" "unprognostic (6.56e-2)" "unprognostic (3.13e-1)" 32.1 43.1 32.6 32.0 34.6 33.7 40.5 35.8 36.7 62.6 34.1 43.5 38.3 43.2 60.4 46.8 34.3 37.2 57.6 32.5 35.9 33.6 45.6 34.3 39.9 34.2 34.5 37.3 67.1 47.3 40.0 55.5 34.8 40.7 43.6 37.0 68.4 52.6 39.7 38.6 36.7 46.1 34.6 31.1 42.0 32.0 34.4 41.8 50.8 38.1 44.2 53.3 24.0 37.0 66.1 51.7 72.2 54.9 137.5 103.2 83.0 101.5 113.9 89.6 113.8 132.8 84.2 97.0 59.7 143.2 61.0 75.9 82.3 96.0 102.2 57.8 81.2 107.5 41.2 198.8 138.4 90.2 62.9 79.2 102.9 90.0 148.3 95.7 98.9 64.5 92.4 72.4 80.3 103.2 85.5 87.0 74.3 109.9 49.3 68.4 64.5 115.0 112.9 91.8 59.3 54.3 58.4 91.6 95.9 59.0 60.8 73.6 93.5 82.8 56.2 79.5 55.7 81.1 56.2 112.4 86.6 58.3 95.6 48.3 38.3 27.0 53.0 40.6 81.7 44.8 59.1 63.4 48.3 40.7 58.0 48.5 9.6 64.5 46.8 63.9 57.0 62.8 32.6 34.6 35.8 36.7 32.5 35.9 34.2 34.5 34.8 34.6 34.4 37.0 28.7 41.7 36.6 15.0 46.7 37.2 39.6 83.4 38.1 30.6 33.0 22.5 40.9 27.1 64.2 20.2 31.3 114.4 49.3 39.2 56.7 69.1 196.6 16.2 34.4 32.1 31.3 35.1 20.1 78.1 112.1 48.4 48.4 32.7 20.3 25.7 38.9 45.0 46.4 42.1 23.0 63.9 48.8 22.7 29.7 380.7 58.7 23.9 48.0 22.5 46.3 39.3 35.0 27.2 31.7 69.7 41.9 49.7 171.9 62.1 31.7 43.7 23.1 34.8 59.2 27.5 40.3 39.6 39.6 47.1 36.1 229.7 43.4 44.9 48.2 67.7 TLK1 "KIAA0137, PKU-BETA" ENSG00000198586 "Tousled like kinase 1" Q9UKI8 2 170990823-171231314 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016043 Approved Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA016043: AB_1858027" "unprognostic (2.13e-2)" "unprognostic (3.87e-1)" "unprognostic (7.36e-2)" "unprognostic (6.00e-3)" "unprognostic (2.00e-1)" "unprognostic (6.78e-2)" "unprognostic (2.47e-2)" "unprognostic (7.60e-2)" "unprognostic (1.61e-1)" "unprognostic (5.26e-2)" "unprognostic (2.57e-1)" "unprognostic (1.11e-1)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.53e-1)" 7.7 10.2 5.9 10.7 8.3 11.1 12.3 4.1 10.5 12.7 5.1 13.0 9.4 10.6 5.4 9.4 9.5 9.6 7.0 10.1 4.6 13.0 14.8 8.4 15.0 3.5 7.3 14.0 10.4 18.0 6.2 15.2 3.4 11.8 12.3 15.8 9.2 14.6 16.3 8.5 11.8 11.7 4.4 13.2 13.5 17.7 10.6 13.8 17.6 5.5 15.7 11.7 8.3 7.6 16.6 15.6 22.0 17.3 15.4 15.3 24.7 22.5 31.9 21.8 18.2 21.8 25.9 34.2 18.7 33.4 23.6 13.7 28.5 24.6 23.8 42.1 14.9 39.1 18.5 28.0 16.5 50.3 19.0 16.7 24.6 43.4 28.4 23.0 24.3 21.2 42.3 27.4 13.2 20.3 43.8 15.5 20.6 15.5 8.9 31.9 26.9 34.7 17.7 30.9 25.0 19.7 24.7 16.7 16.1 14.9 13.8 17.0 33.2 19.3 24.0 12.7 17.8 24.5 43.0 59.7 23.9 20.1 19.9 11.1 3.1 5.7 5.2 2.6 7.3 8.3 8.3 5.7 3.0 8.3 9.3 6.2 4.2 8.1 5.3 4.4 8.5 5.2 5.9 8.3 4.1 10.5 10.1 4.6 3.5 7.3 3.4 4.4 10.6 7.6 34.2 51.3 27.8 135.8 76.7 41.3 33.2 27.1 30.7 34.8 45.9 28.4 32.1 37.1 29.2 51.5 60.5 82.7 42.6 55.8 88.0 29.2 58.1 29.5 33.9 34.5 23.9 33.7 196.2 32.7 52.7 30.3 37.8 38.4 27.3 39.5 27.5 40.0 27.4 45.4 161.0 36.7 36.7 29.0 30.4 32.0 43.2 54.7 37.4 74.0 29.1 26.6 49.4 84.9 92.0 35.6 36.5 44.8 66.3 51.0 33.4 58.0 30.7 77.5 0.0 41.6 29.6 31.1 54.9 24.5 39.1 174.9 66.4 59.2 33.9 43.0 METTL8 "FLJ13984, TIP" ENSG00000123600 "Methyltransferase like 8" 2 171317405-171434802 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035421 Uncertain Approved Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Cytosol "HPA035421: AB_10670116" "unprognostic (3.13e-1)" "unprognostic (2.72e-1)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.76e-1)" "unprognostic (3.76e-1)" "unprognostic (1.43e-4)" "unprognostic (2.94e-3)" "unprognostic (7.29e-2)" "unprognostic (6.52e-3)" "unprognostic (4.83e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.45e-1)" "unprognostic (2.04e-1)" "unprognostic (2.10e-3)" "unprognostic (2.59e-3)" 3.6 2.8 2.8 3.2 4.7 3.6 3.7 2.5 3.9 3.4 1.8 5.3 2.2 3.0 2.1 8.6 2.4 2.8 2.5 2.6 1.9 3.1 3.6 2.0 3.5 2.7 2.4 2.2 1.7 2.1 1.2 2.6 2.9 3.9 5.2 1.6 2.1 4.0 3.6 6.8 3.6 6.4 2.0 3.3 2.1 4.2 2.8 2.1 1.8 2.3 3.9 5.2 3.8 4.0 10.3 7.4 5.0 13.0 11.7 14.1 19.1 12.8 9.8 11.1 10.0 13.8 13.5 25.1 9.5 8.1 8.2 10.0 17.7 19.4 13.9 10.8 9.9 15.0 6.5 25.0 11.1 17.0 9.1 12.5 24.7 16.0 28.1 2.6 18.6 10.9 26.7 4.1 9.7 13.5 14.3 4.8 16.9 8.3 8.8 7.0 15.4 21.9 9.1 6.8 12.2 5.1 14.5 11.4 9.2 6.6 9.4 7.0 13.8 11.4 6.1 7.6 7.5 3.6 13.0 15.0 7.2 15.9 11.2 0.5 2.1 0.5 3.4 2.7 4.4 3.4 4.4 3.3 2.1 5.1 1.9 2.1 0.7 3.7 1.6 6.7 4.8 2.5 2.8 4.7 2.5 3.9 2.6 1.9 2.7 2.4 2.9 2.0 2.8 4.0 8.1 6.4 6.1 25.1 72.3 25.5 10.7 18.3 27.9 8.4 10.6 9.1 8.2 14.3 14.1 3.7 2.1 15.5 13.1 8.4 11.7 7.6 13.3 4.0 19.2 8.2 6.7 16.2 28.7 6.2 21.2 14.9 6.1 6.1 6.3 18.5 7.5 10.6 11.8 11.8 33.0 5.7 12.2 9.8 10.2 4.1 14.0 11.9 10.6 17.8 11.4 6.3 7.2 29.1 48.2 8.8 5.3 16.1 24.2 20.4 9.8 18.3 6.4 9.2 6.6 10.8 10.8 11.8 21.3 32.8 26.7 12.9 18.3 23.0 13.7 10.0 DCAF17 "C2orf37, FLJ13096" ENSG00000115827 "DDB1 and CUL4 associated factor 17" Q5H9S7 2 171434217-171485052 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Deafness, Diabetes mellitus, Hypotrichosis, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 56.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053339, HPA055040" Uncertain Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA053339: AB_2682119, HPA055040: AB_2682680" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.03e-2)" "unprognostic (1.60e-1)" "unprognostic (5.98e-2)" "unprognostic (5.60e-2)" "unprognostic (2.67e-2)" "unprognostic (2.30e-3)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.12e-2)" "unprognostic (1.41e-1)" "unprognostic (4.27e-1)" "prognostic unfavorable (7.10e-4)" "unprognostic (2.79e-2)" 3.9 4.5 5.2 5.4 6.6 3.4 6.4 6.6 6.1 6.1 4.3 5.6 4.5 6.2 6.3 4.4 4.6 3.8 3.5 5.1 5.7 5.6 4.5 3.8 7.2 5.5 5.2 7.1 5.0 6.0 3.8 5.3 5.8 5.0 4.6 13.9 4.3 4.5 3.9 7.2 4.7 4.6 5.5 6.4 4.4 5.7 6.9 7.8 10.2 4.3 6.0 5.6 5.4 10.6 8.5 6.9 8.9 10.6 11.0 11.7 13.6 7.3 7.5 7.3 6.8 8.3 5.5 24.4 5.4 9.1 5.5 8.2 9.1 9.0 9.9 11.4 6.2 11.3 6.2 15.0 11.2 16.2 7.9 9.2 11.6 9.3 20.7 8.6 8.0 7.6 17.9 8.2 10.1 5.2 17.9 14.9 13.2 6.2 4.3 13.4 11.7 13.4 6.2 7.6 7.8 11.3 6.9 5.8 7.4 8.3 4.5 8.3 9.6 8.4 7.6 4.8 6.4 12.4 18.3 20.5 8.9 8.2 8.8 1.1 1.3 0.5 2.3 1.5 3.4 1.3 1.8 1.7 1.0 1.8 2.0 2.5 0.0 1.1 1.3 0.8 1.8 1.6 5.2 6.6 6.6 6.1 5.1 5.7 5.5 5.2 5.8 5.5 6.9 10.6 5.8 0.0 7.5 17.9 8.9 4.7 4.7 4.2 8.6 10.1 7.8 6.0 5.0 7.2 3.1 7.3 12.5 6.5 6.0 4.4 9.8 4.8 2.2 6.2 10.7 5.2 10.2 6.9 18.0 3.9 5.7 5.8 8.2 4.9 3.8 8.2 2.5 7.7 5.6 8.4 23.5 4.5 6.1 8.4 4.6 3.6 6.2 5.0 3.6 15.0 4.4 8.8 5.2 24.6 56.5 6.6 2.0 6.0 6.4 6.3 5.5 6.2 6.1 15.2 0.0 6.7 7.2 13.5 17.1 8.7 5.1 5.6 7.5 9.0 4.3 5.0 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 DYNC1I2 "DIC74, DNCI2" ENSG00000077380 "Dynein cytoplasmic 1 intermediate chain 2" Q13409 2 171687409-171750158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Transport" "Motor protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033836, HPA040619, HPA053987" Supported Supported "Nucleoli,Endoplasmic reticulum,Microtubules,Cytosol" NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Cytosol" "Nucleoli, Microtubules" "CAB033836: AB_2093633, HPA040619: AB_2677045, HPA053987: AB_2682334" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-2)" "unprognostic (8.15e-2)" "unprognostic (8.90e-2)" "unprognostic (1.37e-3)" "unprognostic (2.51e-3)" "unprognostic (6.30e-3)" "unprognostic (1.23e-1)" "unprognostic (1.89e-2)" "unprognostic (1.40e-2)" "unprognostic (4.19e-1)" "prognostic favorable (8.04e-4)" "unprognostic (1.76e-1)" "unprognostic (1.47e-1)" "unprognostic (1.35e-3)" "unprognostic (6.42e-2)" 65.1 58.5 89.2 44.4 121.1 23.1 65.3 122.6 185.9 62.3 70.4 62.3 54.3 74.5 51.0 68.3 47.1 58.6 65.9 89.2 101.4 80.0 41.3 51.7 38.7 130.5 116.2 71.7 38.7 68.2 29.4 76.2 124.1 59.9 64.7 63.5 46.7 60.3 51.0 48.8 51.0 80.4 104.0 41.4 49.3 55.9 112.9 60.0 56.3 57.7 47.4 72.3 53.3 155.5 87.5 55.0 167.0 61.9 151.2 144.0 94.2 149.2 115.7 122.9 133.7 96.5 84.4 79.2 127.7 178.8 168.0 86.2 132.5 143.5 159.8 30.1 59.7 69.3 65.7 109.6 75.5 80.0 71.7 113.0 133.4 152.3 97.3 171.7 219.1 76.5 112.1 21.3 246.1 54.4 68.9 65.7 77.0 127.0 55.5 68.7 149.8 58.3 163.3 138.0 105.8 116.6 82.7 65.6 90.6 126.0 64.1 77.3 238.3 185.9 91.9 75.2 90.9 26.3 54.0 64.5 126.8 64.2 139.2 209.6 93.9 49.2 50.7 98.0 54.3 77.2 58.1 59.4 68.7 71.1 51.7 49.5 5.8 64.4 100.1 111.8 66.2 39.6 89.2 121.1 122.6 185.9 89.2 101.4 130.5 116.2 124.1 104.0 112.9 155.5 146.2 198.7 60.6 30.3 49.2 50.6 59.2 138.5 19.9 73.1 101.7 87.1 75.4 158.7 124.8 169.2 64.6 101.9 46.3 169.5 131.0 207.6 129.5 118.2 147.3 117.1 84.3 95.2 102.4 161.5 107.5 91.2 42.8 172.6 102.3 69.3 174.9 150.7 101.1 80.8 104.9 140.0 116.0 148.1 39.8 48.0 128.6 75.9 35.6 45.9 156.2 91.3 70.0 35.7 182.4 189.2 126.9 138.0 22.7 44.7 139.2 270.3 108.0 128.9 111.7 61.4 111.0 248.4 95.2 43.2 60.0 115.6 46.7 60.6 123.9 58.5 SLC25A12 Aralar ENSG00000115840 "Solute carrier family 25 member 12" O75746 2 171783405-171999859 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 97.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 97.7;Excitatory neurons: 148.5;Inhibitory neurons: 175.2;Oligodendrocyte precursor cells: 111.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035333, HPA035334" Enhanced Uncertain "Nuclear speckles,Cytosol" NA NA 9100 "Cluster 32: T-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Cytosol "HPA035333: AB_10603028, HPA035334: AB_2674577" "unprognostic (3.24e-2)" "unprognostic (2.52e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (4.21e-3)" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (4.96e-2)" "unprognostic (7.76e-2)" "unprognostic (1.13e-1)" "prognostic favorable (2.91e-8)" "unprognostic (8.64e-3)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" 11.1 11.5 8.5 4.0 9.0 2.8 11.6 9.3 12.3 11.5 6.1 25.2 2.2 13.4 4.3 12.7 11.7 3.7 62.7 8.9 9.0 13.4 1.8 7.1 4.4 6.9 6.7 14.5 3.9 12.0 17.1 3.2 6.8 13.7 6.1 15.8 16.8 9.5 97.0 14.5 10.7 8.5 5.8 8.9 16.4 6.1 7.4 5.6 15.1 51.1 5.2 16.2 12.4 8.4 4.9 3.0 4.2 8.0 9.5 11.7 0.0 5.3 11.2 7.7 7.3 2.2 3.2 14.5 2.6 7.5 4.3 4.3 7.9 8.5 10.7 6.3 10.4 6.9 4.4 5.5 3.8 14.8 4.9 12.6 7.0 11.0 2.3 4.1 8.0 7.0 5.0 5.2 4.4 3.2 9.7 6.5 3.0 3.8 4.7 9.6 4.7 7.4 8.0 4.5 5.1 1.6 2.6 8.5 4.0 2.5 2.8 3.1 6.4 6.2 2.0 6.0 3.2 8.8 4.2 13.6 9.1 7.5 2.9 0.0 0.4 0.1 1.0 0.4 0.8 0.7 0.5 0.9 0.4 0.5 0.9 1.5 0.0 0.9 0.7 0.1 0.7 0.4 8.5 9.0 9.3 12.3 8.9 9.0 6.9 6.7 6.8 5.8 7.4 8.4 9.8 0.0 9.8 71.2 11.3 6.9 10.2 13.2 19.9 25.5 9.3 11.8 97.7 0.0 18.4 18.4 25.0 7.5 10.7 11.6 19.6 1.7 3.2 5.0 10.3 8.7 14.4 6.9 148.5 3.3 1.8 15.1 12.8 6.1 10.8 7.3 7.9 0.6 4.5 37.0 175.2 6.1 16.2 8.4 5.4 2.1 12.5 7.2 16.0 25.3 9.7 19.8 5.2 111.6 44.1 2.0 4.7 24.5 19.5 4.6 4.1 13.2 11.2 25.5 13.1 12.5 16.6 7.8 9.1 16.8 7.7 1.2 15.0 11.0 7.6 8.3 HAT1 KAT1 ENSG00000128708 "Histone acetyltransferase 1" O14929 2 171922448-171983686 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036788, CAB037191" Supported Supported Nucleoplasm NA NA 27000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "CAB037191: AB_477070, HPA036788: AB_10672267" "unprognostic (1.76e-1)" "unprognostic (1.01e-2)" "unprognostic (7.39e-3)" "unprognostic (8.24e-3)" "unprognostic (2.76e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (5.72e-5)" "unprognostic (2.71e-2)" "unprognostic (9.08e-3)" "unprognostic (3.69e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.23e-2)" "unprognostic (6.89e-2)" "unprognostic (1.80e-1)" "unprognostic (3.97e-2)" "unprognostic (6.69e-2)" 27.7 27.0 14.3 33.5 15.5 59.8 41.4 15.9 19.2 26.8 15.3 27.7 19.9 24.6 16.7 26.6 24.4 24.6 31.4 13.1 16.2 32.2 30.2 25.7 48.7 15.0 14.6 23.2 30.0 37.9 16.9 30.6 15.5 29.0 30.7 28.8 32.8 24.0 67.7 23.8 21.7 29.3 16.1 27.7 23.6 20.1 15.5 50.7 32.8 50.8 47.5 39.0 19.6 17.3 132.4 61.5 106.6 98.8 55.2 56.8 75.2 133.9 88.9 144.4 149.9 144.3 88.2 147.0 85.0 81.5 122.7 101.3 116.7 109.5 220.5 83.5 115.8 131.1 91.5 131.0 26.7 165.5 77.9 34.2 62.2 191.0 63.6 45.5 92.6 100.4 136.5 93.1 166.5 91.8 131.1 148.3 89.0 158.9 63.9 102.8 134.4 99.4 85.3 130.2 67.8 55.4 112.4 62.4 118.1 81.5 86.4 164.5 47.5 129.8 99.2 109.5 137.1 40.9 100.5 173.8 87.6 117.8 113.8 47.6 35.3 53.7 32.8 42.0 40.6 35.5 34.9 34.0 27.4 30.7 33.9 37.6 40.3 44.6 59.2 14.3 49.2 34.0 14.3 15.5 15.9 19.2 13.1 16.2 15.0 14.6 15.5 16.1 15.5 17.3 55.6 35.3 28.9 13.7 49.7 74.2 117.7 129.7 46.1 24.2 36.4 42.3 49.5 25.8 66.2 27.6 33.3 77.5 43.5 19.0 82.2 45.2 70.3 33.1 32.3 43.2 14.3 103.1 28.6 46.5 83.1 43.7 15.8 28.9 40.6 30.7 28.9 20.1 51.8 28.6 45.3 20.9 111.9 29.5 36.3 14.7 30.7 34.5 32.0 16.9 28.8 53.4 43.3 21.6 28.0 27.8 21.0 36.9 50.8 52.0 18.2 46.0 65.4 42.0 39.5 43.8 51.3 65.7 67.5 28.8 52.7 58.3 49.0 43.9 29.4 64.1 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999943-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.5;Oligodendrocyte precursor cells: 35.7;Oligodendrocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299, HPA077742" Uncertain Uncertain Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421, HPA077742: " "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 4.4 4.9 4.3 2.4 4.5 3.5 3.9 3.7 5.0 5.4 3.7 4.6 2.3 4.5 2.8 3.4 6.7 2.0 4.8 4.1 5.1 4.5 6.0 2.3 2.8 4.1 4.1 11.9 8.1 2.2 4.3 1.8 4.6 5.6 3.2 2.5 4.1 3.7 7.8 3.4 4.1 2.8 3.6 5.8 4.6 2.8 4.3 1.2 3.6 5.6 2.0 4.2 3.8 5.0 3.6 2.8 4.1 13.5 5.9 7.7 8.3 4.1 4.1 6.4 4.1 6.4 4.7 1.8 7.2 4.3 6.6 6.4 9.1 7.2 6.5 6.3 10.6 10.2 7.8 8.6 6.2 6.1 2.6 5.8 10.9 6.4 10.2 5.5 3.6 6.9 14.8 5.1 4.9 4.4 3.5 8.2 7.4 10.4 3.4 7.7 3.5 3.3 4.5 5.0 8.4 3.2 2.9 5.8 10.2 3.6 6.7 8.1 4.4 8.1 6.4 5.0 4.0 6.3 6.1 4.0 5.8 11.9 7.9 0.0 0.0 0.0 0.4 0.4 0.2 0.3 0.5 0.2 0.1 0.7 0.5 1.1 0.0 0.4 0.0 0.0 0.4 0.2 4.3 4.5 3.7 5.0 4.1 5.1 4.1 4.1 4.6 3.6 4.3 5.0 6.1 0.0 4.6 23.8 15.4 5.6 10.3 7.5 22.8 5.8 9.2 8.9 4.5 7.2 3.5 3.7 2.1 4.1 2.7 1.3 7.9 2.5 1.2 2.7 14.7 5.4 0.0 16.8 19.6 3.5 4.7 10.9 8.2 2.5 4.5 17.9 6.4 6.4 3.9 5.0 39.5 2.9 2.0 2.5 2.2 2.3 33.5 2.2 5.4 14.0 1.0 3.7 9.2 35.7 35.5 1.4 1.3 26.4 9.9 4.3 0.6 5.7 2.0 6.1 13.1 18.1 9.5 9.8 12.2 11.6 5.7 1.9 7.5 14.5 5.7 5.1 DLX1 ENSG00000144355 "Distal-less homeobox 1" P56177 2 172084740-172089677 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 18.8" "Cell type enriched" "Detected in some" 23 "Inhibitory neurons: 30.4" "Cancer enhanced" "Detected in many" "prostate cancer: 11.1" "Region enhanced" "Detected in many" "hypothalamus: 18.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 134.5;U-138 MG: 36.9;WM-115: 42.1" "Group enriched" "Detected in many" 5 "basal ganglia: 28.6;olfactory bulb: 82.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 48.8" "HPA007175, HPA045884" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA007175: , HPA045884: AB_10960361" "unprognostic (2.14e-2)" "unprognostic (5.09e-2)" "unprognostic (3.92e-2)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (7.92e-3)" "unprognostic (8.86e-2)" "unprognostic (2.80e-2)" "unprognostic (2.03e-1)" "unprognostic (5.74e-2)" "unprognostic (2.04e-1)" "unprognostic (7.40e-9)" "unprognostic (2.22e-1)" "unprognostic (9.19e-2)" "unprognostic (1.25e-1)" "unprognostic (5.91e-3)" 0.1 1.3 5.9 0.2 4.8 0.0 0.1 0.0 4.4 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.5 18.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.1 0.5 0.2 0.1 0.0 0.0 0.1 0.0 3.5 0.0 1.0 0.1 0.3 0.1 0.2 2.7 2.4 0.6 0.6 134.5 2.0 4.5 0.3 3.2 6.5 7.7 4.1 1.0 0.2 0.0 7.8 7.2 7.5 9.4 7.4 1.2 5.2 0.3 33.3 21.1 14.4 5.7 0.1 7.9 15.9 0.0 2.2 1.9 3.2 5.4 0.0 6.7 12.4 0.0 6.3 8.1 0.1 1.9 0.1 0.0 22.9 0.4 15.8 0.0 0.9 4.5 11.3 0.0 6.1 0.8 17.5 0.4 5.2 9.5 7.1 36.9 0.2 16.4 16.4 0.2 0.0 0.1 15.2 21.4 42.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 4.8 0.0 4.4 3.5 18.8 0.0 0.2 0.0 0.0 3.5 2.7 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DLX2 TES-1 ENSG00000115844 "Distal-less homeobox 2" Q07687 2 172099438-172102900 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.0" "Cell type enhanced" "Detected in some" "dendritic cells: 6.5;Early spermatids: 6.9;Gastric mucus-secreting cells: 5.6;Inhibitory neurons: 10.0;Melanocytes: 5.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "hypothalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "AN3-CA: 79.7;HEK 293: 50.8" "Region enhanced" "Detected in many" "olfactory bulb: 29.4" "Region enriched" "Detected in many" 5 "olfactory bulb: 23.2" HPA056965 Approved "Nuclear speckles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "HPA056965: AB_2683291" "unprognostic (8.12e-2)" "unprognostic (3.56e-1)" "unprognostic (2.48e-2)" "unprognostic (1.28e-2)" "unprognostic (4.07e-1)" "unprognostic (2.13e-1)" "unprognostic (8.60e-3)" "unprognostic (3.03e-2)" "unprognostic (2.41e-1)" "unprognostic (8.74e-2)" "unprognostic (3.53e-2)" "unprognostic (3.01e-1)" "unprognostic (6.69e-10)" "unprognostic (9.38e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (7.95e-3)" 0.0 0.3 1.4 0.0 1.1 0.1 0.2 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 79.7 0.5 0.3 2.2 4.3 1.0 0.7 0.2 0.5 0.2 0.0 2.4 2.0 3.8 4.1 2.6 0.3 0.2 0.1 50.8 1.3 8.8 2.0 0.2 0.4 0.3 0.0 3.7 0.1 0.5 0.3 0.0 2.0 0.6 0.0 0.5 0.2 0.1 0.6 0.1 0.0 1.1 0.0 0.4 0.0 0.1 0.1 2.8 0.0 2.1 1.2 5.0 1.3 0.6 0.4 0.4 5.5 0.0 3.0 0.5 0.1 0.1 0.5 4.7 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.1 0.0 0.9 0.4 3.0 0.0 0.0 0.0 0.0 0.5 0.1 1.4 0.0 0.0 0.0 1.3 1.8 0.2 0.9 0.6 0.0 3.1 3.6 0.4 0.0 0.2 0.0 0.0 0.4 6.5 1.0 0.0 0.0 6.9 1.6 0.3 0.5 0.0 0.0 0.1 0.0 0.3 0.2 5.6 1.1 0.0 0.0 0.0 0.0 0.5 0.0 10.0 1.1 0.0 0.0 0.3 0.1 0.0 1.8 5.4 1.0 0.0 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.4 0.1 1.3 0.0 0.1 0.0 0.0 0.3 1.5 0.9 0.7 1.6 0.0 0.4 1.5 0.2 0.6 0.0 ITGA6 CD49f ENSG00000091409 "Integrin subunit alpha 6" P23229 2 172427354-172506459 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 327.2;Basal keratinocytes: 244.7;Urothelial cells: 247.6" "Cancer enhanced" "Detected in all" "head and neck cancer: 144.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 22.9" "Group enriched" "Detected in many" 28 "granulocytes: 22.9;NK-cells: 7.1;T-cells: 12.8" "Cell line enhanced" "Detected in many" "BJ: 326.2;HaCaT: 356.8;HBEC3-KT: 705.8;hTCEpi: 298.9;hTERT-HME1: 301.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009009, HPA012696, HPA027582" Enhanced NA NA 3300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "CAB009009: AB_2128038, HPA012696: AB_1851822, HPA027582: AB_10602606" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (2.59e-2)" "unprognostic (5.96e-2)" "unprognostic (4.93e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (1.19e-1)" "unprognostic (1.61e-3)" "unprognostic (9.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.85e-3)" "unprognostic (1.84e-1)" "prognostic favorable (2.35e-11)" "unprognostic (3.35e-2)" "unprognostic (3.32e-1)" "unprognostic (2.98e-2)" "unprognostic (1.21e-3)" 45.9 8.3 20.1 27.8 16.7 5.8 55.6 16.6 20.3 64.3 42.8 65.4 74.2 43.1 9.5 25.1 25.3 37.2 29.2 17.2 20.9 42.7 8.8 29.3 18.7 20.8 18.8 5.6 42.0 14.0 6.2 76.8 19.3 24.4 62.4 7.3 81.0 30.8 27.7 46.6 67.4 39.0 20.5 41.2 66.1 26.1 25.0 33.9 21.1 42.6 21.4 55.0 26.8 16.5 77.5 64.8 26.7 49.1 1.4 0.9 146.3 326.2 34.6 32.1 20.0 36.2 141.3 0.7 90.9 86.8 73.8 356.8 17.7 705.8 58.1 0.7 16.6 1.9 64.8 58.7 4.8 21.4 2.4 6.2 298.9 2.0 301.4 32.9 209.6 40.8 0.3 5.5 41.6 3.7 5.9 17.8 48.2 214.2 54.5 1.1 82.3 1.6 48.0 106.6 0.8 3.4 61.2 0.1 69.7 28.0 13.1 1.4 97.9 44.9 41.1 84.2 56.8 4.8 3.6 1.9 1.7 7.2 185.0 4.4 0.2 22.9 5.3 0.0 10.7 0.2 6.7 6.4 0.1 0.5 12.8 5.9 0.7 7.1 0.0 0.0 8.1 4.3 20.1 16.7 16.6 20.3 17.2 20.9 20.8 18.8 19.3 20.5 25.0 16.5 327.2 9.6 19.5 88.5 8.8 244.7 236.4 43.4 88.8 1.4 55.0 72.8 32.5 22.8 10.5 27.6 56.3 103.8 14.4 139.6 5.9 34.4 31.2 82.5 34.8 196.0 57.4 1.7 4.0 62.1 26.5 20.8 219.7 149.3 8.2 103.4 11.7 21.5 25.5 1.7 6.1 128.8 20.3 3.2 20.8 46.8 4.1 10.0 51.6 119.9 1.7 1.3 29.9 1.5 8.8 127.9 104.2 2.6 109.0 184.8 54.5 52.2 9.2 13.9 0.0 11.8 18.4 7.7 20.2 141.5 84.0 22.3 30.1 44.0 146.3 247.6 PDK1 ENSG00000152256 "Pyruvate dehydrogenase kinase 1" Q15118 2 172555373-172608669 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.4;Plasma cells: 144.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 8.6;granulocytes: 25.2;T-cells: 21.2" "Cell line enhanced" "Detected in all" "U-266/70: 71.8;U-87 MG: 72.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017554, HPA027376" Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB017554: AB_2161138, HPA027376: AB_1855139" "unprognostic (2.14e-1)" "prognostic unfavorable (7.30e-5)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (6.47e-2)" "unprognostic (1.58e-1)" "unprognostic (1.02e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-3)" "unprognostic (6.44e-2)" "unprognostic (5.44e-3)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.10e-8)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (5.34e-2)" 7.7 16.0 2.5 11.6 3.0 15.8 10.1 5.6 5.3 5.5 2.7 16.7 16.5 4.0 3.1 8.5 3.6 6.0 28.1 3.1 2.1 4.8 11.2 4.2 13.1 2.7 6.7 12.2 6.9 4.3 3.8 6.4 3.2 4.7 13.3 27.1 10.2 5.0 9.0 18.1 9.1 4.4 1.3 10.5 13.6 12.2 5.0 8.3 3.9 7.6 19.1 11.0 7.6 2.5 34.0 1.4 8.4 21.0 3.4 5.1 12.1 29.1 23.4 14.3 30.4 8.6 7.1 32.1 15.8 9.1 11.9 14.5 5.8 18.2 45.5 6.6 11.7 39.3 7.1 10.2 6.2 19.6 14.0 6.6 6.4 10.0 16.6 19.8 7.7 16.7 8.5 21.5 19.2 3.5 12.5 24.5 20.8 6.9 9.2 13.1 13.8 52.5 7.4 10.8 15.7 18.0 7.6 8.8 11.1 7.0 5.6 8.0 9.2 22.7 7.4 12.0 7.9 71.8 44.8 26.9 72.6 14.0 4.6 19.6 3.4 25.2 3.7 2.3 4.2 7.3 5.9 4.0 3.5 8.6 21.2 13.5 12.7 2.2 3.2 0.6 12.2 9.2 2.5 3.0 5.6 5.3 3.1 2.1 2.7 6.7 3.2 1.3 5.0 2.5 9.2 3.2 5.0 12.1 33.7 50.1 5.1 15.8 4.6 29.4 7.0 4.7 35.5 2.8 7.0 3.7 47.9 10.2 9.9 11.9 5.9 8.7 130.4 6.4 7.2 9.6 7.8 4.2 35.4 3.7 13.2 8.5 9.7 12.1 5.7 13.3 19.6 20.2 10.2 55.5 32.7 6.6 12.2 12.0 15.2 43.8 3.4 12.9 30.2 30.9 11.4 7.4 10.3 12.1 14.8 9.6 17.5 3.8 144.8 7.2 6.7 1.9 5.0 18.5 6.6 4.6 11.6 9.6 10.4 8.9 43.3 4.1 17.3 5.3 7.0 6.1 RAPGEF4 "cAMP-GEFII, CGEF2" ENSG00000091428 "Rap guanine nucleotide exchange factor 4" Q8WZA2 2 172735274-173052893 "Predicted intracellular proteins" Exocytosis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 142.3" "Group enriched" "Detected in many" 7 "Excitatory neurons: 441.1;Inhibitory neurons: 416.6;Microglial cells: 142.4;Oligodendrocyte precursor cells: 303.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 21.5;SCLC-21H: 8.3;U-266/70: 11.0;U-266/84: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004388, HPA028968" Approved Approved "Focal adhesion sites" NA NA "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Focal adhesion sites" "CAB004388: AB_670916, HPA028968: AB_2672846" "unprognostic (1.87e-1)" "unprognostic (4.22e-2)" "unprognostic (1.31e-1)" "unprognostic (2.98e-3)" "unprognostic (4.53e-2)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "prognostic favorable (1.32e-4)" "unprognostic (6.32e-2)" "unprognostic (1.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.18e-2)" "unprognostic (5.70e-2)" "unprognostic (2.93e-1)" 5.3 45.6 105.0 1.8 113.1 0.2 6.8 69.8 141.6 6.1 49.1 2.1 2.4 5.6 3.1 2.6 3.4 4.7 7.5 142.3 77.7 5.3 34.6 11.4 2.0 61.2 75.0 13.1 4.5 4.0 6.2 2.6 60.8 4.1 1.6 18.8 2.4 3.3 1.5 14.9 2.3 5.4 55.7 0.6 7.7 4.7 128.3 2.2 5.5 1.7 2.0 5.3 3.2 121.9 0.1 0.2 3.2 0.5 0.1 0.3 0.1 1.1 0.7 0.1 0.3 0.0 3.7 0.0 0.2 0.0 0.2 0.7 2.8 0.7 0.3 0.2 5.9 0.6 2.8 0.0 0.0 3.2 0.9 0.1 0.9 0.0 0.0 3.2 3.5 1.6 0.0 21.5 0.1 0.1 0.2 0.2 0.4 1.8 0.4 0.1 0.7 0.0 0.0 6.6 8.3 3.0 0.1 0.1 1.1 1.6 0.1 0.1 1.0 0.1 0.3 0.0 0.3 11.0 23.0 0.0 0.4 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 105.0 113.1 69.8 141.6 142.3 77.7 61.2 75.0 60.8 55.7 128.3 121.9 14.7 3.2 2.8 23.2 1.9 6.1 1.1 0.1 2.8 3.5 5.5 3.9 6.9 0.0 0.0 0.0 45.9 0.1 0.1 0.0 0.0 1.7 2.5 1.2 0.2 32.4 7.8 0.0 441.1 2.7 0.1 4.8 3.1 0.9 0.0 3.3 23.9 11.8 0.1 1.7 416.6 0.5 0.0 1.2 2.1 1.4 4.4 0.2 3.6 142.4 0.0 1.3 0.0 303.1 28.4 1.5 0.1 1.5 1.6 0.5 0.0 0.0 0.0 9.2 0.0 0.4 1.2 0.7 4.1 1.6 3.8 0.1 0.6 4.2 0.1 0.7 MAP3K20 "MLK7, MLTK, MLTKalpha, MLTKbeta, MRK, ZAK" ENSG00000091436 "Mitogen-activated protein kinase kinase kinase 20" Q9NYL2 2 173075435-173268015 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 261.9;tongue: 279.7" "Cell type enhanced" "Detected in many" "Adipocytes: 57.5;Alveolar cells type 2: 57.7;Cytotrophoblasts: 52.6;Endometrial stromal cells: 96.7;Granulosa cells: 100.7;Smooth muscle cells: 83.2;Theca cells: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 15.5" "Group enriched" "Detected in many" 5 "dendritic cells: 15.5;monocytes: 9.4" "Cell line enhanced" "Detected in many" "U-138 MG: 176.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017205 Approved Supported Cytosol NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA017205: AB_1858933" "unprognostic (2.90e-2)" "unprognostic (9.99e-3)" "unprognostic (4.63e-3)" "unprognostic (1.98e-1)" "unprognostic (7.63e-2)" "unprognostic (5.02e-2)" "unprognostic (2.34e-2)" "unprognostic (3.89e-3)" "unprognostic (2.83e-2)" "unprognostic (9.27e-2)" "unprognostic (4.54e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.41e-6)" "unprognostic (2.34e-1)" "unprognostic (1.86e-1)" "unprognostic (2.23e-1)" "unprognostic (1.19e-2)" 71.0 11.4 9.5 20.5 9.7 4.7 21.4 10.3 8.5 44.9 15.7 65.8 13.0 76.4 18.6 50.0 48.0 31.4 195.7 9.3 12.1 7.5 25.2 22.5 9.8 13.8 14.7 69.5 11.7 49.3 3.8 27.6 11.2 44.0 20.9 2.5 12.4 57.1 261.9 14.1 19.2 75.0 11.1 12.5 31.5 10.6 12.5 11.5 16.4 279.7 10.2 56.1 21.2 9.4 34.6 28.6 22.0 29.1 62.7 92.5 13.8 121.9 94.7 55.9 59.6 19.5 22.2 26.5 31.2 122.5 48.8 22.9 33.1 64.6 124.2 52.0 22.0 43.3 30.5 4.1 24.8 39.3 43.8 74.7 27.2 105.2 164.2 46.3 37.5 28.5 19.8 4.9 36.8 14.8 24.8 19.0 12.2 28.9 16.0 36.2 45.0 0.1 13.6 19.6 12.9 12.4 47.0 11.3 19.7 35.6 12.9 20.9 37.9 176.3 71.4 53.1 27.9 0.1 0.1 5.5 126.2 10.6 18.9 0.2 9.4 0.0 1.0 8.3 1.0 1.6 0.8 1.7 15.5 2.5 0.0 0.8 2.6 0.5 8.2 0.3 0.8 3.4 9.5 9.7 10.3 8.5 9.3 12.1 13.8 14.7 11.2 11.1 12.5 9.4 57.5 38.5 57.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 20.0 44.4 0.0 0.0 7.4 11.0 0.0 52.6 2.3 0.0 1.9 43.9 0.0 36.7 96.7 14.1 0.0 0.0 0.0 27.6 21.9 36.5 0.0 35.6 5.1 100.7 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 15.5 0.0 0.0 0.0 0.0 38.6 0.0 0.0 1.4 0.0 0.0 1.9 13.1 0.0 0.0 0.0 83.2 0.0 0.0 0.0 0.0 21.6 3.6 70.5 0.0 0.0 CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.4;lymphoid tissue: 50.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.7;Intestinal goblet cells: 40.7;Leydig cells: 53.7;Undifferentiated cells: 124.2" "Cancer enhanced" "Detected in all" "colorectal cancer: 43.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 7.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 279.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA005565: AB_2078680" "unprognostic (1.67e-3)" "unprognostic (2.26e-1)" "unprognostic (1.21e-1)" "unprognostic (1.54e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (7.54e-2)" "prognostic unfavorable (5.50e-4)" "unprognostic (4.96e-2)" "unprognostic (2.83e-1)" "unprognostic (8.97e-3)" "unprognostic (0.00e+0)" "unprognostic (4.53e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (2.47e-2)" 1.7 0.3 0.7 13.1 0.6 23.0 2.4 0.5 0.7 12.6 6.5 25.5 30.7 13.8 3.3 10.1 3.8 1.5 0.8 0.7 1.2 0.5 0.3 1.6 37.5 0.7 0.9 1.1 1.7 0.3 0.1 7.4 0.7 3.0 29.5 0.4 2.5 1.2 3.1 11.7 32.4 3.4 0.7 2.4 14.3 6.0 1.2 50.1 0.5 0.8 41.2 2.8 6.7 1.0 44.2 33.3 76.4 83.3 3.6 14.0 79.9 26.0 9.2 60.3 67.2 51.6 54.4 122.1 32.2 15.8 23.5 45.0 122.4 46.6 87.0 59.2 67.4 27.6 24.6 66.0 3.8 181.2 25.1 11.4 3.9 32.8 27.3 7.8 28.0 158.1 67.4 27.2 17.7 35.4 279.7 181.7 90.4 103.4 22.7 194.4 58.2 77.3 29.5 38.2 22.3 39.2 40.8 13.4 22.0 67.9 0.3 70.5 13.0 39.3 16.8 12.9 48.5 7.4 17.1 173.0 24.4 99.8 34.0 0.0 0.5 0.0 1.1 0.0 0.4 1.9 3.0 5.9 3.5 0.3 0.2 1.0 0.2 3.2 0.0 0.5 7.9 2.3 0.7 0.6 0.5 0.7 0.7 1.2 0.7 0.9 0.7 0.7 1.2 1.0 1.0 0.0 0.6 0.7 3.0 20.3 14.9 3.3 14.8 0.0 2.6 6.5 1.1 0.0 0.3 0.0 0.0 45.7 1.6 17.1 0.0 0.2 0.9 3.2 33.0 3.4 12.2 33.6 0.1 0.2 29.9 4.1 22.4 6.8 0.0 18.5 0.0 0.2 10.4 0.0 10.5 40.7 4.1 1.0 4.4 2.2 53.7 2.3 3.6 0.0 1.2 0.7 0.0 0.5 0.1 1.0 11.1 34.6 3.8 5.3 11.9 0.0 0.1 0.0 0.0 1.1 7.2 13.8 28.9 21.8 15.9 10.1 9.1 2.7 124.2 3.8 SP3 SPR-2 ENSG00000172845 "Sp3 transcription factor" Q02447 2 173880850-173965702 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004580, HPA032145, HPA032146" Supported Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Nucleoplasm Cytosol "CAB004580: AB_628274, HPA032145: , HPA032146: AB_2732465" "unprognostic (1.94e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-1)" "unprognostic (2.39e-3)" "unprognostic (2.50e-1)" "unprognostic (4.92e-2)" "unprognostic (5.54e-3)" "unprognostic (6.36e-2)" "unprognostic (2.76e-3)" "unprognostic (3.27e-1)" "unprognostic (5.01e-3)" "unprognostic (1.68e-1)" "prognostic unfavorable (2.46e-5)" "unprognostic (2.78e-1)" "unprognostic (2.07e-1)" "unprognostic (8.02e-2)" "unprognostic (1.69e-1)" 32.6 19.8 15.8 35.2 16.0 53.1 43.1 21.3 19.8 50.9 16.1 34.3 26.9 45.1 34.6 32.1 37.1 28.9 23.8 14.2 17.1 29.7 40.1 29.9 46.1 16.9 16.7 40.3 24.9 43.1 13.2 49.1 16.4 31.9 38.9 21.0 26.1 30.4 22.5 38.5 29.6 36.3 16.3 38.6 27.0 25.2 15.5 68.0 47.5 33.7 53.8 33.7 28.0 18.5 41.6 34.5 74.6 45.8 91.8 82.3 83.5 47.5 67.1 62.2 66.1 56.8 59.7 65.1 39.3 65.0 46.3 41.0 57.8 46.0 91.7 55.2 21.2 65.9 33.9 54.0 45.5 60.4 48.9 60.6 53.2 72.9 63.6 48.4 49.4 51.3 51.4 86.8 65.7 44.4 84.0 49.9 66.1 60.1 37.8 74.2 68.5 53.0 48.4 55.8 67.8 48.1 67.1 38.1 52.4 81.7 30.0 80.0 44.1 70.6 61.8 47.5 50.4 58.8 46.7 85.8 53.0 41.6 67.2 8.9 9.4 13.0 11.6 7.0 12.9 9.5 12.3 12.3 9.9 7.4 13.8 12.8 27.3 21.9 10.3 6.2 13.8 9.9 15.8 16.0 21.3 19.8 14.2 17.1 16.9 16.7 16.4 16.3 15.5 18.5 36.1 19.2 22.9 44.7 55.2 57.6 31.7 25.7 64.9 29.1 36.8 23.4 18.8 14.3 23.3 20.2 27.1 30.9 67.9 37.9 11.7 18.6 4.3 22.3 57.8 33.9 30.5 31.7 52.7 19.3 42.7 43.9 17.9 29.5 23.5 31.3 32.2 43.8 24.6 23.5 50.7 28.8 20.3 54.1 72.8 7.1 45.4 55.6 42.7 81.5 39.0 30.5 46.4 60.3 74.7 30.8 22.9 36.9 63.7 34.2 22.1 24.4 26.6 20.2 19.7 40.4 53.4 10.5 20.4 48.6 57.0 34.6 50.8 26.0 29.0 59.0 OLA1 "GTPBP9, PTD004" ENSG00000138430 "Obg like ATPase 1" Q9NTK5 2 174072447-174248599 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035790, HPA041443" Approved Enhanced Cytosol NA NA 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA035790: AB_10601977, HPA041443: AB_2677483" "unprognostic (3.30e-1)" "unprognostic (1.06e-1)" "unprognostic (2.23e-2)" "unprognostic (2.85e-3)" "unprognostic (1.20e-1)" "unprognostic (3.08e-3)" "prognostic unfavorable (9.73e-8)" "unprognostic (6.51e-3)" "unprognostic (7.66e-2)" "unprognostic (1.09e-2)" "unprognostic (3.50e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-3)" "unprognostic (4.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.62e-2)" "unprognostic (9.75e-2)" 42.2 44.3 39.7 38.2 42.7 53.7 57.3 42.5 48.9 34.3 30.0 48.0 50.1 34.7 38.8 58.1 38.0 35.1 57.4 44.5 43.8 56.4 43.0 23.5 47.9 38.0 36.6 31.1 56.3 44.1 27.4 42.0 40.1 41.1 52.7 42.5 36.3 33.6 105.6 52.0 45.7 37.0 38.0 24.6 35.2 48.8 40.7 58.3 59.7 93.1 53.3 48.3 31.0 39.1 181.4 84.1 134.9 225.5 70.1 152.2 243.0 142.1 142.8 194.2 147.1 200.9 104.4 246.5 138.9 114.5 143.9 139.9 165.3 164.6 227.3 113.7 142.5 231.3 76.4 209.9 135.3 264.3 90.2 134.8 200.6 206.3 217.4 177.4 174.5 88.0 256.8 82.3 170.3 116.6 241.4 272.9 159.1 193.9 273.0 180.4 217.8 170.7 245.1 192.0 218.3 124.7 96.8 141.6 206.2 142.2 101.2 220.6 127.5 127.1 161.4 128.5 210.8 76.2 207.3 190.5 124.6 180.0 115.4 18.1 24.9 7.4 16.2 24.2 23.4 17.9 18.6 20.8 37.1 16.4 21.5 21.2 2.1 26.1 20.0 22.5 25.3 22.7 39.7 42.7 42.5 48.9 44.5 43.8 38.0 36.6 40.1 38.0 40.7 39.1 43.2 35.3 33.0 57.5 49.0 62.7 73.5 92.4 76.8 47.3 86.0 83.8 68.3 47.1 57.0 31.3 35.5 153.7 47.7 44.6 103.7 145.1 267.8 37.1 55.2 47.8 70.7 92.5 132.6 105.3 112.8 53.0 60.1 43.1 41.2 73.3 29.3 25.8 97.3 33.7 129.8 79.6 65.1 59.6 54.4 99.5 40.4 55.9 32.0 65.6 83.1 60.3 52.5 101.6 101.8 112.8 51.8 51.1 56.3 84.2 78.4 141.7 36.1 35.9 26.3 69.7 92.3 104.8 35.9 113.7 64.1 105.9 55.9 94.6 107.6 79.3 SP9 ZNF990 ENSG00000217236 "Sp9 transcription factor" P0CG40 2 174334954-174338500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 3.2" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 11.1" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.2;fHDF/TERT166: 5.5;HEK 293: 2.2;THP-1: 11.6" "Group enriched" "Detected in many" 6 "basal ganglia: 5.8;olfactory bulb: 11.7" "Group enriched" "Detected in many" 4 "basal ganglia: 5.6;olfactory bulb: 21.6" HPA062616 Uncertain Approved Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "HPA062616: AB_2684808" "unprognostic (2.04e-2)" "unprognostic (6.94e-3)" "unprognostic (1.44e-1)" "unprognostic (3.95e-1)" "unprognostic (7.55e-3)" "unprognostic (8.54e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" 0.0 0.0 2.5 0.0 2.9 0.0 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.7 1.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 7.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 5.5 0.0 0.1 0.2 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 3.2 0.7 1.6 0.1 0.3 0.1 0.0 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 CIR1 CIR ENSG00000138433 "Corepressor interacting with RBPJ, CIR1" Q86X95 2 174348022-174395712 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 187.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 187.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015784, HPA061442" Approved Supported "Nuclear speckles" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA015784: AB_1846782, HPA061442: AB_2732664" "unprognostic (3.17e-3)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (2.40e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.00e-2)" "unprognostic (4.39e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.27e-1)" "unprognostic (3.66e-2)" "prognostic unfavorable (1.04e-7)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (8.10e-3)" "prognostic favorable (2.04e-5)" 26.7 23.8 36.3 23.4 38.1 67.3 35.9 38.5 61.1 26.6 39.5 27.7 25.8 27.4 43.5 20.3 28.3 23.4 28.7 36.0 37.3 25.9 27.5 26.7 31.1 36.8 37.0 33.7 24.9 27.4 25.1 29.8 36.6 26.2 26.3 23.6 24.9 26.0 30.7 30.5 26.7 20.7 35.9 35.0 25.5 31.4 36.3 32.3 29.0 25.2 29.5 24.0 24.2 40.1 20.4 11.4 26.5 21.2 36.3 50.4 39.2 32.9 46.5 32.3 39.5 21.5 30.7 14.1 30.3 32.4 28.3 24.0 22.1 23.4 38.6 26.1 29.1 29.4 17.8 34.9 35.1 35.2 26.0 41.7 41.9 35.5 26.5 55.6 32.4 24.9 30.7 30.8 31.0 19.5 44.1 55.6 24.5 33.2 31.6 24.7 38.1 42.2 38.4 32.1 30.7 36.1 22.7 28.7 52.9 45.7 21.6 51.6 33.6 26.1 19.0 24.9 17.3 34.6 31.4 5.2 37.4 18.2 23.3 71.0 33.8 55.9 28.4 31.7 28.4 41.2 32.2 30.5 21.4 40.5 33.4 30.9 187.8 45.3 33.9 39.5 37.2 28.3 36.3 38.1 38.5 61.1 36.0 37.3 36.8 37.0 36.6 35.9 36.3 40.1 82.0 118.6 79.8 30.0 80.8 28.6 52.2 118.6 39.3 51.7 40.6 66.8 61.4 61.5 101.2 42.3 31.3 72.7 116.5 69.1 119.3 67.3 201.5 192.2 79.7 58.7 51.4 102.5 30.4 78.7 58.1 69.9 30.1 79.6 81.6 59.1 75.7 58.6 63.8 45.4 33.7 81.9 85.5 93.0 30.3 43.4 107.2 75.3 33.8 22.5 108.2 85.7 111.2 30.2 37.3 57.7 79.8 82.4 49.1 37.5 91.6 114.0 202.3 56.2 72.3 71.4 72.1 219.5 54.7 25.4 32.0 116.0 80.5 62.6 53.5 45.7 SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA034689: AB_2674282, HPA034690: AB_10670574" "unprognostic (5.39e-3)" "unprognostic (4.58e-2)" "unprognostic (2.06e-2)" "unprognostic (3.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (5.85e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (6.62e-3)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" 16.4 16.4 11.8 9.9 14.4 5.2 13.5 14.7 16.0 9.5 7.0 12.9 18.5 11.9 11.4 16.2 10.4 11.2 26.0 10.8 13.6 20.2 22.0 12.2 11.4 14.6 13.4 13.2 14.7 27.7 14.0 13.1 13.6 15.2 13.2 22.8 11.0 12.5 40.5 13.8 14.3 14.0 12.9 11.8 12.4 10.6 14.1 12.4 20.3 35.8 12.1 10.4 8.3 18.5 15.9 9.7 25.8 22.8 18.8 21.1 13.7 24.1 19.0 18.2 22.0 9.6 11.4 3.0 15.6 24.2 14.0 15.5 19.3 21.1 23.9 34.8 17.8 29.7 21.1 7.5 27.8 22.8 15.0 23.5 25.4 34.4 24.5 20.4 21.8 16.7 20.2 11.1 25.0 18.0 18.9 22.2 12.0 35.4 41.0 9.3 25.7 17.5 21.2 16.5 16.0 44.5 16.6 16.2 30.7 26.4 21.8 21.7 15.7 20.9 10.9 25.6 21.0 29.4 32.8 0.5 22.9 11.2 21.8 7.2 5.2 2.2 4.8 3.3 3.4 8.6 5.1 4.6 5.1 11.0 7.8 6.3 20.0 6.9 4.3 8.0 5.6 2.6 11.8 14.4 14.7 16.0 10.8 13.6 14.6 13.4 13.6 12.9 14.1 18.5 7.8 9.6 15.6 18.6 7.0 3.6 12.1 23.7 12.5 12.8 7.9 6.3 22.8 4.3 12.5 9.2 10.4 10.7 3.8 8.4 13.7 9.1 5.1 9.4 8.3 6.0 6.0 11.6 21.0 9.8 6.3 6.9 11.2 5.4 8.8 9.5 8.6 8.7 9.3 18.5 26.3 7.3 20.3 5.8 2.2 4.0 4.7 6.2 3.6 6.5 6.1 22.6 7.2 27.6 25.7 12.2 4.0 6.8 10.3 5.4 9.9 12.5 13.6 15.0 0.0 8.2 7.1 18.9 7.1 20.4 4.8 6.8 5.8 13.0 6.4 9.7 GPR155 "DEP.7, DEPDC3, FLJ31819, PGR22" ENSG00000163328 "G protein-coupled receptor 155" Q7Z3F1 2 174431571-174487094 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 83.4;stomach 1: 52.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 125.1;Excitatory neurons: 99.4;Inhibitory neurons: 131.1;Melanocytes: 152.9;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 14.6;WM-115: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036159, HPA057384" Approved Approved "Nuclear bodies,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies, Cytosol" "HPA036159: AB_10671835, HPA057384: AB_2683424" "unprognostic (3.91e-2)" "unprognostic (7.93e-2)" "unprognostic (3.14e-2)" "unprognostic (4.11e-4)" "unprognostic (5.03e-2)" "unprognostic (2.48e-1)" "unprognostic (8.49e-2)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.91e-2)" "unprognostic (2.48e-2)" "unprognostic (4.82e-2)" "unprognostic (2.59e-2)" "unprognostic (9.90e-2)" "unprognostic (1.82e-2)" "unprognostic (4.54e-2)" 4.3 9.7 8.7 5.9 16.3 2.3 2.4 6.5 12.1 2.4 83.4 10.2 3.8 1.9 12.3 5.9 1.6 5.7 7.0 12.2 5.3 20.1 7.3 3.0 6.3 5.5 5.3 2.5 18.2 8.9 2.3 4.4 5.2 7.5 3.7 10.0 3.6 8.4 4.7 13.2 4.0 6.1 3.5 5.4 52.6 2.2 7.1 3.0 8.3 4.4 3.6 4.1 2.7 6.1 0.7 0.3 0.8 2.0 4.9 2.7 0.5 3.8 1.3 0.6 2.1 0.3 0.2 2.2 1.2 2.8 1.3 0.2 1.3 1.1 2.1 0.8 1.5 2.3 1.1 0.2 0.9 0.7 1.1 3.9 3.1 1.9 0.6 4.0 1.0 3.0 0.3 5.5 4.2 0.6 1.6 0.8 0.4 2.3 1.5 1.9 5.6 1.0 2.0 1.3 5.9 5.0 1.2 0.8 2.0 2.5 0.3 0.3 2.6 2.7 1.0 3.9 0.5 14.6 2.2 0.3 3.0 0.6 9.9 1.3 2.2 0.1 1.8 4.0 1.6 1.1 3.1 2.9 0.6 1.0 2.5 3.9 7.3 3.6 5.7 0.3 5.5 1.4 8.7 16.3 6.5 12.1 12.2 5.3 5.5 5.3 5.2 3.5 7.1 6.1 18.5 12.8 3.6 31.3 9.8 42.7 4.0 4.0 29.0 34.9 5.8 6.1 26.0 2.8 6.8 11.0 125.1 1.5 12.2 0.6 1.9 1.9 0.7 1.4 24.1 9.8 12.7 15.2 99.4 6.0 1.2 9.7 9.7 0.6 1.3 4.0 16.1 16.1 6.1 50.5 131.1 0.8 2.0 50.4 23.0 1.8 14.9 27.0 152.9 8.4 34.3 16.7 11.3 130.2 21.2 3.5 0.1 32.0 14.3 3.1 0.4 41.7 0.5 25.8 0.0 16.9 9.5 3.3 3.2 7.5 28.6 0.8 25.7 52.4 1.0 1.8 WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 126.9" "Cell type enhanced" "Detected in many" "dendritic cells: 172.7;monocytes: 187.2;NK-cells: 245.1;Oligodendrocytes: 217.2;Plasma cells: 162.8;T-cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 209.1;Karpas-707: 296.8;U-266/70: 233.0" "Low region specificity" "Detected in all" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 520000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB009737: AB_2288577, HPA003739: AB_1858783, HPA070706: AB_2686300" "unprognostic (4.76e-2)" "unprognostic (4.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.88e-2)" "unprognostic (1.87e-1)" "unprognostic (2.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (3.65e-2)" "unprognostic (5.43e-2)" "unprognostic (1.58e-1)" "unprognostic (2.50e-2)" 31.0 14.7 14.2 93.0 37.2 56.8 21.0 36.1 20.5 30.6 11.1 26.0 18.2 22.4 11.5 14.2 14.4 34.8 16.0 14.9 28.8 13.0 16.4 31.8 126.9 46.2 38.6 12.3 7.3 12.9 4.8 33.5 42.3 14.9 20.8 3.4 17.7 23.0 5.9 9.9 32.5 29.1 27.9 89.7 21.8 4.7 35.1 66.4 15.4 11.5 110.5 31.5 17.0 53.8 0.7 7.0 16.3 0.2 40.4 70.9 16.9 31.1 26.4 12.1 18.7 1.9 1.4 209.1 9.2 47.0 15.6 0.5 2.8 0.0 15.1 144.8 4.1 106.5 26.9 0.0 15.1 94.9 167.2 29.6 5.1 27.7 2.6 16.0 25.0 18.7 3.3 296.8 34.4 0.1 106.6 87.1 19.1 0.0 1.4 90.0 6.6 37.9 11.3 0.7 2.6 33.8 0.3 8.8 18.7 30.4 0.4 46.8 21.2 41.0 11.5 30.1 29.9 233.0 165.2 113.7 60.4 64.7 111.7 41.5 35.4 87.2 71.6 37.3 59.4 35.1 47.6 71.1 26.1 28.6 38.0 51.4 166.1 57.4 43.7 11.2 57.7 54.7 14.2 37.2 36.1 20.5 14.9 28.8 46.2 38.6 42.3 27.9 35.1 53.8 32.1 19.2 21.7 27.7 134.5 12.5 6.3 0.9 2.8 2.1 3.3 4.3 10.5 1.5 4.6 3.7 25.0 2.0 172.7 0.3 5.9 1.7 40.2 3.3 21.9 30.8 4.9 30.1 5.3 11.6 82.5 40.5 9.7 2.1 67.2 2.1 36.8 3.7 86.2 0.0 7.2 1.6 0.0 142.2 128.0 96.9 25.1 139.8 26.6 98.4 187.2 1.2 245.1 120.6 217.2 16.8 0.8 18.0 162.8 5.0 0.2 35.9 0.1 3.4 13.1 15.7 21.4 4.4 4.1 1.2 11.1 4.1 208.1 8.8 2.1 3.1 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CHN1 "ARHGAP2, CHN, DURS2, n-chimerin, RhoGAP2" ENSG00000128656 "Chimerin 1" P15882 2 174798809-175005381 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 772.6" "Cell type enhanced" "Detected in many" "Astrocytes: 195.2;Excitatory neurons: 596.4;Inhibitory neurons: 111.7;Microglial cells: 97.4;Oligodendrocyte precursor cells: 149.8" "Cancer enhanced" "Detected in all" "glioma: 18.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 6.5;memory CD8 T-cell: 2.1;T-reg: 8.0" "Lineage enriched" "Detected in single" 18 "T-cells: 8.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036111 Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA036111: AB_10671241" "unprognostic (3.18e-3)" "unprognostic (4.19e-2)" "unprognostic (9.69e-2)" "unprognostic (3.42e-3)" "unprognostic (1.92e-1)" "unprognostic (2.65e-2)" "unprognostic (7.45e-2)" "unprognostic (9.14e-2)" "unprognostic (3.71e-2)" "unprognostic (1.34e-2)" "unprognostic (5.29e-2)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (7.31e-3)" "unprognostic (4.07e-1)" "unprognostic (2.08e-2)" "unprognostic (9.46e-2)" 11.8 13.3 368.6 7.3 445.9 0.8 10.5 194.0 772.6 9.2 170.6 10.2 3.3 7.9 38.3 6.9 6.5 11.1 15.1 492.6 241.5 4.7 2.1 19.6 21.5 210.2 225.4 5.8 4.2 43.4 36.3 38.6 210.5 17.0 5.1 39.5 3.2 9.6 2.7 3.8 7.5 13.1 192.4 5.5 7.1 21.3 239.1 3.1 10.2 3.7 18.7 8.7 6.7 422.8 0.4 17.4 57.6 16.3 14.7 67.4 0.4 45.6 186.7 65.1 97.0 0.3 5.4 0.5 1.6 71.8 39.9 2.0 68.0 1.9 30.3 1.3 32.9 11.1 20.1 3.8 34.4 6.4 1.7 53.6 1.9 31.6 11.1 16.1 33.6 30.0 0.7 1.9 57.2 11.8 29.3 2.5 71.7 2.6 23.7 8.2 70.3 0.8 0.9 0.6 71.3 76.3 41.3 0.5 7.3 36.0 3.2 2.2 10.1 26.8 3.9 9.8 20.6 6.4 33.7 0.7 6.7 0.4 6.6 0.4 0.1 0.1 0.3 0.1 0.8 0.2 6.5 2.1 0.0 0.1 1.3 0.4 0.4 0.2 0.2 0.3 8.0 1.0 368.6 445.9 194.0 772.6 492.6 241.5 210.2 225.4 210.5 192.4 239.1 422.8 15.4 3.2 1.9 195.2 1.6 4.5 0.3 0.0 0.0 85.1 7.3 1.4 6.2 1.5 2.6 3.7 27.1 1.2 0.5 0.1 0.0 0.3 24.1 5.3 5.6 17.9 2.4 0.0 596.4 0.6 1.1 28.4 2.0 3.6 0.0 5.1 10.4 0.5 2.7 77.4 111.7 0.0 0.0 0.0 4.0 23.2 3.1 0.9 7.2 97.4 0.0 59.1 0.0 149.8 88.1 0.6 0.0 5.3 1.3 0.6 0.0 0.3 1.0 14.1 13.1 23.8 27.3 17.8 23.6 0.1 3.7 2.1 12.5 5.1 0.2 0.3 ATF2 "CRE-BP1, CREB2, HB16, TREB7" ENSG00000115966 "Activating transcription factor 2" P15336 2 175072250-175168382 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 153.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003769, HPA022134" Supported Supported Enhanced Nucleoplasm NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "CAB003769: AB_562241, HPA022134: AB_1845138" "unprognostic (1.11e-1)" "unprognostic (2.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.93e-1)" "unprognostic (9.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.28e-2)" "unprognostic (3.70e-2)" "unprognostic (6.47e-2)" "unprognostic (7.17e-2)" "unprognostic (4.02e-2)" "unprognostic (4.40e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (7.21e-3)" "unprognostic (6.70e-2)" 16.8 20.2 15.6 15.2 17.6 16.4 19.5 23.3 25.7 25.7 4.1 15.1 13.0 21.8 21.6 14.3 18.9 17.8 12.1 19.3 15.5 22.5 27.8 15.4 19.7 16.2 14.9 26.0 18.9 24.0 13.9 20.4 17.2 18.3 15.7 21.8 17.9 17.7 12.5 10.0 13.6 18.1 12.3 17.6 14.3 21.0 13.3 30.2 32.3 23.1 21.1 18.8 13.0 19.8 14.1 12.1 35.1 23.4 30.6 32.3 16.1 22.3 38.1 26.6 38.1 26.6 25.4 21.1 23.9 26.6 31.2 13.3 26.9 13.5 41.2 26.6 15.6 29.3 19.8 58.3 34.4 27.8 29.7 24.4 29.8 34.4 40.5 35.0 37.0 19.4 24.4 31.6 30.1 10.5 45.2 34.4 32.7 23.6 27.2 38.3 16.1 32.5 39.1 11.8 29.3 23.9 27.9 8.6 33.0 28.2 19.3 30.4 23.5 30.8 16.1 16.9 13.6 30.3 48.9 26.9 24.2 26.0 21.2 35.5 16.9 20.1 20.1 15.1 24.3 16.6 17.0 20.9 21.9 14.1 19.6 21.5 10.8 19.8 19.1 12.1 24.4 18.0 15.6 17.6 23.3 25.7 19.3 15.5 16.2 14.9 17.2 12.3 13.3 19.8 43.4 16.0 13.2 47.7 33.5 33.0 15.4 15.6 52.9 22.7 34.0 24.4 22.5 20.0 15.5 23.9 10.4 14.1 37.4 16.5 13.7 12.1 115.4 19.5 30.5 33.8 16.3 20.8 86.6 7.0 13.0 32.2 18.3 28.4 29.8 27.1 17.2 27.0 18.9 40.4 71.3 14.4 18.3 23.3 30.2 153.0 32.6 23.6 30.2 54.4 20.4 32.3 24.7 75.9 84.9 11.9 9.1 28.6 38.8 15.6 11.5 21.6 19.3 27.3 13.1 31.5 33.9 36.3 17.6 30.4 25.3 6.3 32.9 23.7 16.1 13.6 ATP5MC3 ATP5G3 ENSG00000154518 "ATP synthase membrane subunit c locus 3" P48201 2 175176258-175181710 "Metabolic proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1214.0;tongue: 1088.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 880.5;Distal tubular cells: 2666.7;Extravillous trophoblasts: 1022.6;Hofbauer cells: 1008.2;Proximal tubular cells: 2131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (4.45e-3)" "unprognostic (1.67e-1)" "prognostic favorable (9.90e-4)" "unprognostic (1.67e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (3.46e-2)" "unprognostic (6.03e-3)" "unprognostic (1.42e-2)" "unprognostic (7.90e-2)" "unprognostic (4.71e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.31e-6)" "unprognostic (2.86e-1)" "unprognostic (3.93e-1)" "unprognostic (4.55e-2)" "unprognostic (2.31e-2)" 195.7 199.2 134.9 131.1 142.0 141.2 164.5 160.3 155.0 126.4 168.1 343.9 378.7 127.8 126.5 305.3 107.3 75.8 1214.0 143.0 164.7 432.4 385.3 118.1 127.3 153.7 143.6 99.7 120.2 550.6 139.5 102.4 157.3 110.0 315.0 126.5 184.8 114.5 777.9 169.7 297.3 122.2 147.4 131.4 272.4 62.3 154.2 188.9 135.1 1088.5 176.3 171.8 165.4 150.0 268.4 232.3 346.7 381.8 290.0 255.9 387.1 242.7 255.1 334.8 290.9 700.0 216.4 661.1 276.5 272.0 365.7 343.3 440.2 419.9 348.5 278.3 411.7 538.7 312.1 896.6 225.9 702.4 308.8 279.9 317.7 377.5 239.3 257.4 341.9 313.2 587.0 305.1 370.3 361.9 541.1 587.3 460.6 638.4 726.1 417.1 321.5 648.4 664.5 590.9 310.5 196.3 195.1 521.4 557.0 487.5 313.4 567.0 231.6 55.9 263.2 1.7 338.0 239.5 327.1 582.4 319.8 420.8 251.8 115.2 293.9 126.9 168.4 332.1 170.7 202.4 176.5 184.2 425.2 163.2 164.2 181.1 32.6 197.9 309.4 314.5 204.0 438.5 134.9 142.0 160.3 155.0 143.0 164.7 153.7 143.6 157.3 147.4 154.2 150.0 250.4 176.3 157.2 0.0 69.0 0.0 0.0 0.0 0.0 0.0 324.8 399.4 0.0 0.0 125.7 310.8 0.0 880.5 134.2 0.0 2666.7 479.0 0.0 271.2 264.1 79.3 0.0 0.0 0.0 375.2 1022.6 154.1 0.0 301.5 88.3 236.8 0.0 0.0 1008.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 205.5 0.0 0.0 205.7 0.0 0.0 0.0 0.0 391.9 0.0 0.0 26.5 0.0 0.0 2131.8 129.7 0.0 0.0 0.0 181.9 0.0 0.0 0.0 0.0 690.9 81.0 469.5 0.0 0.0 LNPK "KIAA1715, LNP, LNP1, Ul" ENSG00000144320 "Lunapark, ER junction formation factor" Q9C0E8 2 175923882-176002839 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 19.3;Endometrial stromal cells: 24.6;Hofbauer cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 159.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014205 Approved Supported "Nucleoplasm,Endoplasmic reticulum" NA NA 15000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum" Nucleoplasm "HPA014205: AB_2234186" "unprognostic (4.93e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.85e-2)" "unprognostic (1.08e-2)" "unprognostic (8.73e-2)" "unprognostic (1.27e-1)" "unprognostic (3.15e-1)" "unprognostic (2.72e-2)" "unprognostic (3.13e-1)" "unprognostic (4.17e-3)" "unprognostic (1.63e-1)" "unprognostic (9.27e-2)" "unprognostic (2.35e-3)" "unprognostic (3.43e-2)" 13.5 8.9 6.3 7.7 10.1 30.1 9.8 10.2 8.7 12.0 4.2 12.0 7.6 8.6 6.2 13.1 6.3 7.7 12.2 7.6 13.2 8.2 14.4 6.7 7.2 11.3 9.2 10.7 5.5 15.6 6.0 6.1 14.1 10.1 10.2 24.1 6.4 8.2 34.1 12.1 7.5 9.6 11.3 5.9 7.8 24.5 9.3 14.0 8.8 26.8 7.9 7.6 9.2 19.0 24.5 12.3 28.3 40.1 58.5 36.1 14.3 70.8 33.7 32.2 45.1 17.0 28.2 24.4 39.4 31.5 42.3 26.5 26.9 18.9 44.6 37.5 27.4 27.6 14.8 15.2 13.8 47.2 32.9 29.9 17.5 31.4 15.4 26.4 6.0 19.3 28.9 31.5 44.9 16.0 31.4 18.8 9.2 24.9 23.4 31.3 28.6 18.0 13.6 22.2 32.6 32.9 31.3 17.5 24.1 26.6 26.2 15.4 9.2 159.0 23.6 53.9 33.7 18.5 36.6 20.3 49.4 15.2 30.4 3.7 4.2 7.9 4.9 4.8 5.8 4.3 4.2 5.4 3.9 3.3 4.2 6.7 3.4 6.5 4.5 4.4 7.8 3.4 6.3 10.1 10.2 8.7 7.6 13.2 11.3 9.2 14.1 11.3 9.3 19.0 10.8 19.2 13.6 0.0 4.4 0.0 0.0 0.0 0.0 0.0 19.3 15.0 0.0 0.0 6.2 16.5 0.0 5.7 14.5 0.0 5.9 14.0 0.0 10.1 24.6 3.5 0.0 0.0 0.0 9.6 17.3 12.8 0.0 12.7 11.4 10.6 0.0 0.0 24.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 3.3 0.0 0.0 9.1 8.7 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 8.3 7.2 12.0 0.0 0.0 EVX2 ENSG00000174279 "Even-skipped homeobox 2" Q03828 2 176077472-176083913 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 1.4;prostate: 1.3;seminal vesicle: 1.6;testis: 3.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Enteroendocrine cells: 2.4;Late spermatids: 4.7;Paneth cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "midbrain: 1.3;pons and medulla: 1.1" "Not detected" "Not detected" HPA041576 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 29: Early spermatids - Spermatogenesis" "HPA041576: AB_10796347" "unprognostic (2.27e-1)" "unprognostic (1.68e-3)" "unprognostic (1.83e-1)" "unprognostic (3.41e-1)" "unprognostic (5.75e-1)" "unprognostic (3.13e-2)" "unprognostic (2.15e-3)" "unprognostic (2.32e-1)" "unprognostic (4.93e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 1.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 8.7 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.3 HOXD13 "HOX4I, SPD" ENSG00000128714 "Homeobox D13" P35453 2 176092721-176095944 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "cervix: 14.2;intestine: 18.2;prostate: 9.7;seminal vesicle: 16.3;vagina: 17.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 12.4;Distal enterocytes: 5.5;Enteroendocrine cells: 29.0;Intestinal goblet cells: 9.1;Paneth cells: 5.5;Prostatic glandular cells: 6.3;Undifferentiated cells: 9.9;Urothelial cells: 6.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 18.4;HEK 293: 53.3;HL-60: 61.7;JURKAT: 16.7;NB-4: 36.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA064064 Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA064064: AB_2685186" "unprognostic (2.04e-1)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (2.52e-3)" "unprognostic (7.25e-2)" "unprognostic (2.08e-2)" "unprognostic (4.62e-2)" "unprognostic (1.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.82e-4)" "unprognostic (4.95e-2)" "unprognostic (3.70e-2)" "unprognostic (9.98e-3)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.2 0.0 18.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 9.7 7.6 0.0 0.0 16.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.7 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.1 2.2 4.7 0.0 0.0 0.0 0.0 0.0 5.1 0.0 18.4 0.0 2.8 0.0 53.3 8.3 0.0 0.0 0.0 61.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 3.9 0.0 0.0 0.0 0.0 36.3 1.9 0.0 3.0 0.0 0.2 0.0 0.0 0.4 15.2 3.7 3.8 0.0 8.9 0.2 0.0 0.0 0.0 1.8 0.0 0.8 5.1 0.0 0.0 0.0 2.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.9 0.0 0.1 0.1 29.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.4 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 9.9 6.7 HOXD12 HOX4H ENSG00000170178 "Homeobox D12" P35452 2 176099795-176102489 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.5;seminal vesicle: 1.5" "Cell type enriched" "Detected in single" 12 "Cardiomyocytes: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.7;REH: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA059444 Uncertain NA NA "Cluster 37: Intestine - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA059444: AB_2684020" "unprognostic (1.00e-1)" "unprognostic (2.40e-3)" "unprognostic (1.32e-2)" "unprognostic (3.53e-2)" "unprognostic (1.71e-2)" "unprognostic (1.36e-2)" "unprognostic (7.11e-2)" "unprognostic (4.54e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.4 0.2 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HOXD11 "HOX4, HOX4F" ENSG00000128713 "Homeobox D11" P31277 2 176104216-176109754 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 7.1;intestine: 3.8;kidney: 4.7;prostate: 3.3;vagina: 4.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.7;Collecting duct cells: 22.0;Distal enterocytes: 22.8;Endometrial stromal cells: 29.0;Enteroendocrine cells: 20.6;Urothelial cells: 14.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 21.9;RPTEC TERT1: 2.6;SCLC-21H: 6.1;U-251 MG: 4.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 40 "spinal cord: 3.9" HPA055155 Supported Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA055155: AB_2682719" "unprognostic (1.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.05e-2)" "unprognostic (1.85e-3)" "unprognostic (2.48e-1)" "unprognostic (1.93e-2)" "unprognostic (2.13e-2)" "unprognostic (6.73e-2)" "unprognostic (5.00e-2)" "unprognostic (2.11e-8)" "unprognostic (2.09e-3)" "unprognostic (2.49e-2)" "unprognostic (2.27e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.1 0.0 3.8 0.0 7.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.3 0.3 0.0 0.0 0.9 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 1.4 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 6.1 0.3 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.4 26.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.0 0.0 0.1 0.0 22.8 9.8 0.0 0.0 1.1 29.0 1.7 20.6 0.0 0.0 0.0 0.1 1.7 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 8.6 0.0 0.0 1.2 0.2 0.9 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.8 1.2 0.0 8.8 0.0 0.3 0.0 0.0 0.0 0.1 2.3 0.1 0.4 0.0 0.9 0.0 0.1 0.0 9.2 14.0 HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.6;endometrium 1: 35.9;vagina: 25.0" "Cell type enhanced" "Detected in some" "Adipocytes: 13.0;Collecting duct cells: 14.7;Distal enterocytes: 10.6;Distal tubular cells: 15.6;Endometrial stromal cells: 25.3;Endothelial cells: 13.5;Enteroendocrine cells: 24.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 12.0;HEK 293: 40.3;RPTEC TERT1: 32.3;SCLC-21H: 11.8;SiHa: 18.4;U-251 MG: 14.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 66 "spinal cord: 6.6" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: AB_2685573" "unprognostic (4.29e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (6.82e-2)" "unprognostic (1.04e-5)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (2.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.86e-1)" "unprognostic (1.27e-1)" 2.0 0.1 0.0 0.5 0.0 0.0 2.6 0.0 0.0 20.6 0.0 18.7 0.0 35.9 0.5 0.5 4.1 0.1 0.0 0.0 0.0 19.9 0.0 0.1 0.5 0.0 0.0 1.6 0.0 0.0 0.0 0.3 0.0 16.8 5.8 0.0 0.1 6.7 0.1 1.5 0.1 18.1 0.0 0.0 0.0 1.4 0.2 0.0 0.1 0.0 0.2 2.2 25.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.2 6.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 4.1 12.0 0.0 0.0 0.5 0.0 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.9 0.0 32.3 0.0 11.8 3.1 18.4 0.0 0.1 2.2 0.0 0.0 2.7 0.0 2.1 1.0 14.4 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.9 6.2 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 14.7 0.0 0.0 0.1 10.6 15.6 0.0 0.0 1.2 25.3 13.5 24.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.8 0.2 1.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.1 1.1 0.0 0.2 0.0 4.4 2.9 HOXD9 "HOX4, HOX4C" ENSG00000128709 "Homeobox D9" P28356 2 176122719-176124937 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 42.2;endometrium 1: 57.8;kidney: 52.1" "Cell type enhanced" "Detected in many" "Adipocytes: 38.4;Collecting duct cells: 23.9;Distal tubular cells: 37.2;Endothelial cells: 39.2;Leydig cells: 34.2;Peritubular cells: 26.7;Sertoli cells: 39.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 11.3;HEK 293: 16.1;RPTEC TERT1: 19.0;SH-SY5Y: 21.7;SK-MEL-30: 13.2;TIME: 16.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 80 "spinal cord: 8.0" HPA068683 Supported Nucleoplasm,Nucleoli NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Nucleoli" "HPA068683: AB_2686018" "unprognostic (1.89e-1)" "unprognostic (9.41e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.03e-2)" "prognostic favorable (9.58e-4)" "prognostic unfavorable (1.08e-5)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (1.54e-2)" "unprognostic (2.56e-3)" "unprognostic (6.71e-2)" "unprognostic (4.77e-3)" "unprognostic (8.38e-2)" "unprognostic (5.94e-2)" "unprognostic (1.89e-1)" "unprognostic (9.44e-2)" 11.6 6.4 0.0 1.3 0.0 0.0 13.9 0.0 0.0 42.2 0.0 29.3 0.1 57.8 14.8 3.5 16.1 0.9 0.2 0.0 0.0 52.1 0.1 0.7 2.4 0.5 0.0 11.1 0.3 0.3 0.0 0.5 0.1 32.3 2.9 0.0 1.2 8.0 1.6 5.8 3.0 15.2 0.5 2.4 0.5 5.6 0.1 0.5 1.4 0.2 0.8 6.1 35.3 0.8 0.1 0.0 0.0 0.0 0.5 0.4 0.2 1.6 1.1 1.3 1.1 0.0 0.0 0.0 11.3 1.6 0.8 7.6 0.1 0.0 0.9 0.0 16.1 0.0 0.8 0.0 0.1 0.0 0.0 3.6 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 19.0 7.1 4.3 21.7 5.5 0.0 13.2 1.1 0.0 0.0 16.9 0.0 3.6 5.3 6.0 0.0 0.0 0.0 1.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.5 0.1 0.8 38.4 0.0 0.0 0.0 0.4 2.4 1.9 0.0 0.0 0.0 0.8 0.5 0.7 0.0 0.0 23.9 0.0 0.0 1.0 8.5 37.2 0.0 0.2 0.8 10.9 39.2 7.8 0.0 0.0 0.0 0.2 1.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.0 3.0 1.3 34.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 26.7 0.0 1.1 0.0 3.0 0.0 0.0 39.5 1.9 3.3 2.2 1.4 0.1 1.8 0.0 1.1 13.9 3.8 0.8 HOXD8 "HOX4, HOX4E" ENSG00000175879 "Homeobox D8" P13378 2 176129694-176132695 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 99.6;kidney: 76.2" "Cell type enhanced" "Detected in many" "Adipocytes: 51.8;Collecting duct cells: 60.7;Distal tubular cells: 213.2;Early spermatids: 124.6;Leydig cells: 51.3;Peritubular cells: 53.8;Spermatocytes: 82.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "medulla oblongata: 1.5;spinal cord: 4.0;white matter: 5.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 45.4;RPTEC TERT1: 74.8;TIME: 32.5" "Not detected" "Not detected" "Region enriched" "Detected in single" 70 "spinal cord: 34.6" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.22e-1)" "unprognostic (6.31e-2)" "unprognostic (2.19e-3)" "unprognostic (2.68e-2)" "unprognostic (3.35e-1)" "unprognostic (3.49e-1)" "unprognostic (2.56e-3)" "prognostic unfavorable (3.78e-4)" "unprognostic (2.79e-1)" "unprognostic (1.40e-2)" "unprognostic (3.93e-1)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (4.80e-2)" "unprognostic (5.21e-2)" "unprognostic (8.31e-2)" "unprognostic (2.80e-2)" 16.4 20.6 0.0 4.8 0.0 0.0 18.8 0.0 0.0 13.3 0.0 10.8 1.2 19.5 99.6 2.7 17.2 3.1 0.9 0.0 0.0 76.2 0.3 0.9 4.9 1.5 0.0 34.2 1.4 1.1 0.0 0.7 0.8 6.0 4.9 0.0 1.7 24.0 7.8 4.8 8.6 13.1 4.0 10.5 1.6 20.1 0.0 1.0 3.5 1.5 1.3 6.5 9.2 5.8 13.7 2.1 0.0 0.0 8.8 14.1 0.3 1.7 7.2 2.2 0.2 0.1 0.1 0.0 16.7 10.8 1.7 0.1 4.7 0.5 5.4 0.0 6.4 2.3 0.8 0.0 2.9 1.3 0.8 24.7 45.4 0.3 6.7 0.0 22.9 4.4 0.2 0.1 3.7 0.1 0.1 0.4 0.2 0.0 2.6 0.0 4.9 0.2 74.8 9.6 14.2 26.4 4.3 0.0 28.4 1.2 0.0 0.1 32.5 1.1 8.9 15.4 9.1 0.0 0.0 0.0 21.1 0.0 26.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.8 4.0 0.0 5.8 51.8 0.0 1.1 0.0 0.5 2.7 2.1 0.0 0.6 0.0 0.7 0.6 2.3 0.0 0.0 60.7 0.0 0.0 0.2 2.7 213.2 0.0 124.6 0.7 9.4 36.4 4.8 0.0 0.0 0.0 0.0 14.9 0.0 0.3 0.0 0.0 2.5 0.0 0.1 0.0 0.0 1.8 0.0 0.0 3.4 29.9 51.3 0.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 53.8 0.0 1.3 0.5 25.1 0.7 0.0 32.9 14.1 9.8 82.1 20.4 0.2 2.8 0.1 1.0 31.9 3.4 1.1 HOXD3 "HOX1D, HOX4, HOX4A" ENSG00000128652 "Homeobox D3" P31249 2 176136612-176173102 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 42.1" "Cell type enhanced" "Detected in some" "Adipocytes: 6.6;Collecting duct cells: 9.2;Distal tubular cells: 15.6;Early spermatids: 14.4;Endothelial cells: 6.5;Theca cells: 4.7" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Group enriched" "Detected in many" 8 "medulla oblongata: 8.9;pons: 5.7;spinal cord: 5.7;white matter: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 9.7;HSkMC: 11.2;RPTEC TERT1: 12.0;SCLC-21H: 14.5;SH-SY5Y: 10.1" "Region enriched" "Detected in single" 35 "pons and medulla: 3.5" "Group enriched" "Detected in some" 6 "medulla oblongata: 4.1;pons: 1.1;spinal cord: 3.0" "HPA051831, HPA063671" Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "HPA051831: , HPA063671: AB_2685083" "unprognostic (1.13e-1)" "unprognostic (3.28e-1)" "unprognostic (1.52e-2)" "unprognostic (6.50e-2)" "unprognostic (1.31e-1)" "unprognostic (7.07e-2)" "unprognostic (1.97e-2)" "unprognostic (1.54e-2)" "unprognostic (9.56e-2)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.56e-1)" "unprognostic (2.57e-4)" "unprognostic (1.47e-3)" "unprognostic (1.55e-1)" "unprognostic (3.44e-1)" "unprognostic (7.44e-2)" 3.2 2.3 0.2 0.8 0.4 0.0 2.8 0.4 0.3 3.2 0.1 1.0 0.3 6.9 42.1 0.7 6.8 0.6 0.2 0.2 0.4 7.9 0.0 0.2 0.8 8.9 0.8 5.5 0.2 0.1 0.0 0.1 5.7 1.7 0.6 0.0 0.5 7.1 0.7 0.9 0.8 4.1 5.7 0.7 0.3 1.7 0.4 0.2 0.4 0.0 0.2 1.0 2.0 4.9 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 1.7 0.2 0.0 0.4 0.0 0.0 0.1 3.6 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.9 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 12.0 0.9 14.5 10.1 0.2 0.1 4.6 0.2 0.0 0.0 1.0 0.2 0.2 1.5 0.8 0.0 0.2 0.0 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.4 0.3 0.2 0.4 8.9 0.8 5.7 5.7 0.4 4.9 6.6 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.3 15.6 0.0 14.4 0.1 2.1 6.5 1.2 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.8 3.5 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.0 0.0 0.3 4.5 0.0 0.1 0.3 2.9 0.0 0.0 0.0 1.3 1.1 0.8 0.5 0.0 1.3 0.0 0.1 4.7 0.6 0.1 HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.4;epididymis: 28.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Collecting duct cells: 16.5;Early spermatids: 3.7;Endothelial cells: 3.6;Leydig cells: 4.7;Proximal tubular cells: 6.5;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in many" 21 "medulla oblongata: 10.6;pons: 5.6;spinal cord: 8.1;white matter: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 16.6;HEK 293: 39.7;RPTEC TERT1: 29.6;SK-MEL-30: 11.0" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 6.0;spinal cord: 7.8" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" 6.9 8.3 0.0 1.6 0.0 0.0 7.4 0.0 0.1 7.1 0.0 7.3 1.0 24.4 28.0 1.1 14.3 1.5 0.6 0.0 0.0 18.5 0.0 0.4 1.7 10.6 0.3 15.1 0.6 0.1 0.0 0.4 5.6 2.9 2.0 0.0 0.7 11.1 2.8 2.4 6.2 9.7 8.1 7.2 1.0 3.0 0.0 0.2 1.2 0.5 0.4 2.7 4.0 7.3 0.5 0.3 0.0 0.0 2.0 3.0 0.0 0.2 0.9 0.1 1.1 0.9 0.0 0.0 16.6 3.4 0.7 0.2 2.6 0.0 0.4 0.0 39.7 0.5 0.0 0.0 0.5 0.0 0.1 9.3 2.6 0.0 0.5 0.2 6.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 29.6 4.1 2.5 4.2 0.6 0.0 11.0 0.6 0.0 0.0 5.0 0.5 0.2 2.9 2.1 0.0 0.1 0.0 2.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.3 5.6 8.1 0.0 7.3 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 3.7 0.1 1.1 3.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.7 2.6 4.7 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 0.0 0.1 0.3 6.5 0.0 0.0 6.6 0.6 0.9 0.3 0.4 0.0 0.6 0.0 0.1 3.0 1.3 0.0 HOXD1 "HOX4, HOX4G" ENSG00000128645 "Homeobox D1" Q9GZZ0 2 176188668-176190907 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.9;epididymis: 7.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 18.5;Distal enterocytes: 20.3;Distal tubular cells: 25.4;Endothelial cells: 18.8;Intestinal goblet cells: 20.6;Oligodendrocytes: 28.0;Proximal enterocytes: 22.0;Undifferentiated cells: 28.6" "Cancer enriched" "Detected in many" 5 "ovarian cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.6;Hep G2: 7.2;RPTEC TERT1: 21.3;RT4: 16.9;SCLC-21H: 5.7" "Region enriched" "Detected in single" 5 "pons and medulla: 1.1" "Low region specificity" "Detected in many" "HPA040062, HPA056900" Enhanced Nucleoplasm NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA040062: AB_2676826, HPA056900: AB_2683270" "unprognostic (8.78e-2)" "unprognostic (9.97e-2)" "unprognostic (7.11e-3)" "unprognostic (1.06e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-2)" "unprognostic (7.33e-2)" "unprognostic (4.10e-2)" "unprognostic (2.85e-1)" "unprognostic (2.44e-1)" "unprognostic (9.64e-2)" "unprognostic (4.02e-1)" "unprognostic (1.54e-5)" "unprognostic (4.33e-3)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" 2.0 0.2 1.7 0.5 5.2 0.0 1.6 6.1 5.0 0.3 0.8 2.9 0.3 0.4 7.5 0.5 4.8 0.7 0.1 1.6 3.3 6.5 0.0 3.2 0.4 19.9 5.8 0.4 0.2 0.0 0.0 0.0 8.2 1.0 2.0 0.0 0.2 2.6 0.1 0.6 3.3 0.3 6.5 1.1 0.4 1.7 5.3 0.1 0.1 0.3 0.1 2.2 0.4 10.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 6.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 7.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 21.3 16.9 5.7 1.0 0.0 0.0 1.2 0.8 0.0 0.0 3.9 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 5.2 6.1 5.0 1.6 3.3 19.9 5.8 8.2 6.5 5.3 10.1 14.2 3.2 18.5 0.0 0.1 4.2 0.2 0.0 0.0 0.0 0.9 1.3 0.1 0.0 2.5 7.3 0.0 0.0 0.1 20.3 25.4 0.0 0.1 0.2 0.2 18.8 6.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 20.6 0.0 0.0 5.6 0.4 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 28.0 0.1 13.2 0.4 0.9 0.7 22.0 3.2 0.0 0.0 0.0 0.6 1.1 3.4 9.5 0.3 2.6 0.0 0.5 0.5 28.6 2.7 MTX2 ENSG00000128654 "Metaxin 2" O75431 2 176269395-176338025 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 201.5;Spermatocytes: 247.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031550, HPA031551, HPA031552" Approved Approved Supported Nucleoli,Mitochondria "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Mitochondria Nucleoli "HPA031550: AB_10599733, HPA031551: AB_10601442, HPA031552: AB_10794616" "unprognostic (2.61e-1)" "unprognostic (9.86e-2)" "unprognostic (6.54e-2)" "prognostic unfavorable (5.06e-4)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (1.05e-2)" "unprognostic (1.29e-1)" "unprognostic (2.87e-2)" "unprognostic (3.97e-2)" "unprognostic (1.80e-2)" "unprognostic (8.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.03e-1)" "unprognostic (9.92e-2)" "unprognostic (3.15e-2)" "unprognostic (1.33e-2)" 20.4 37.4 31.8 15.2 33.6 9.2 27.0 32.8 46.7 22.1 35.9 31.2 22.8 18.7 39.3 38.1 28.9 14.5 49.8 33.3 34.4 46.4 30.8 15.6 14.2 33.9 32.0 21.1 26.3 48.1 29.5 25.8 33.2 26.4 35.5 47.3 20.4 22.6 74.4 23.4 20.2 25.7 34.0 15.6 24.4 64.3 33.5 18.2 20.4 70.9 20.8 25.1 24.7 35.6 52.2 31.0 60.8 37.8 40.0 45.9 58.3 54.5 52.0 49.8 58.3 53.1 55.8 66.4 91.4 49.1 79.9 34.5 67.1 67.6 67.9 66.6 49.4 63.9 39.1 94.9 62.7 98.9 20.7 51.1 83.5 52.2 89.1 60.3 72.0 64.3 86.8 50.2 59.6 47.4 34.9 102.9 58.3 101.8 45.5 0.0 44.0 60.8 142.4 93.3 87.0 74.4 45.7 60.9 120.7 116.4 33.7 64.0 63.5 49.2 43.5 52.1 57.9 55.4 62.1 79.8 61.1 49.7 60.8 8.0 9.3 4.1 9.6 15.8 13.1 18.9 12.4 11.1 14.8 13.7 14.9 15.4 0.0 19.6 14.4 12.1 16.9 9.9 31.8 33.6 32.8 46.7 33.3 34.4 33.9 32.0 33.2 34.0 33.5 35.6 34.4 19.2 22.6 50.6 20.8 31.1 36.2 130.9 37.5 0.0 38.2 43.8 69.2 31.5 63.6 57.0 0.0 78.8 11.1 38.8 201.5 51.8 22.3 60.9 25.7 31.4 41.5 19.5 106.0 39.5 63.3 30.2 28.1 33.9 43.1 25.7 16.4 33.7 47.8 0.0 106.3 47.7 103.7 21.7 15.7 18.8 35.4 19.6 35.6 43.1 26.1 0.0 12.3 93.5 180.2 49.8 26.1 32.7 23.1 48.2 39.6 106.3 63.8 0.0 39.5 24.9 52.4 247.8 127.1 56.5 41.9 65.0 18.8 55.8 52.6 53.7 HNRNPA3 HNRPA3 ENSG00000170144 "Heterogeneous nuclear ribonucleoprotein A3" P51991 2 177212563-177223958 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001666, HPA005812, HPA066381" Supported Enhanced Nucleoplasm NA NA 1800000 "Cluster 6: Non-specific - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA001666: AB_1850836, HPA005812: AB_2667441, HPA066381: AB_2685666" "unprognostic (2.85e-2)" "prognostic favorable (4.87e-4)" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (2.14e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-5)" "unprognostic (2.46e-1)" "unprognostic (3.15e-3)" "unprognostic (2.80e-3)" "unprognostic (3.65e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (9.57e-7)" "unprognostic (6.95e-2)" "unprognostic (3.04e-1)" "unprognostic (4.55e-2)" "unprognostic (1.10e-2)" 162.9 119.0 101.6 210.8 104.5 235.2 144.2 107.5 114.6 183.8 98.8 185.3 129.2 180.1 178.1 244.6 164.3 75.4 118.4 93.7 124.1 193.6 144.3 175.2 232.9 111.8 103.1 208.2 141.4 130.5 137.5 158.5 106.9 141.0 194.7 181.7 138.8 118.1 136.3 179.9 152.3 164.2 103.8 174.7 143.1 175.8 108.6 308.3 176.0 93.0 304.8 153.3 189.2 108.1 657.6 432.9 934.3 469.8 248.2 221.2 717.8 489.3 235.7 382.8 358.5 885.1 337.4 1315.9 366.5 388.4 518.3 370.6 944.2 616.7 712.9 609.6 556.2 996.1 620.3 1727.6 264.8 1064.7 584.0 249.8 288.3 569.9 422.1 217.9 537.3 587.4 723.1 414.3 492.1 891.1 746.9 444.4 507.3 762.5 405.0 947.2 790.1 414.2 547.9 1227.6 545.1 484.7 729.6 228.1 316.4 700.8 325.6 652.5 582.2 476.3 540.4 338.0 719.0 387.6 759.5 1117.2 305.4 699.5 320.0 8.9 21.2 10.8 25.0 22.6 20.2 21.2 20.0 22.0 23.4 20.4 17.5 18.1 8.2 23.5 23.0 37.8 25.9 14.5 101.6 104.5 107.5 114.6 93.7 124.1 111.8 103.1 106.9 103.8 108.6 108.1 274.8 166.7 255.1 84.5 277.4 351.8 429.6 442.1 224.8 192.8 155.2 135.1 64.2 114.4 302.7 160.0 98.0 512.7 368.9 200.7 121.3 257.2 47.2 296.5 387.2 289.7 275.0 288.6 56.9 273.8 563.0 231.4 184.0 343.0 278.1 222.6 196.7 165.0 342.7 148.0 70.5 315.0 193.3 221.0 372.5 44.0 204.7 258.3 192.1 73.1 311.1 187.1 232.8 65.9 88.6 276.1 184.0 209.5 336.6 288.9 136.8 156.7 257.8 164.4 151.2 319.3 461.9 362.8 208.3 331.1 330.5 496.0 307.9 214.1 310.7 382.6 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 AGPS "ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY" ENSG00000018510 "Alkylglycerone phosphate synthase" O00116 2 177392746-177567024 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 262.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030209, HPA030210, HPA030211" Supported Supported Peroxisomes "Intracellular and membrane" NA NA 69000 "Cluster 26: Non-specific - Mitochondria" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Peroxisomes "HPA030209: AB_10600634, HPA030210: AB_10600202, HPA030211: AB_10602195" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "unprognostic (1.76e-3)" "unprognostic (3.79e-2)" "unprognostic (8.34e-2)" "unprognostic (3.78e-2)" "prognostic unfavorable (8.62e-6)" "unprognostic (1.23e-2)" "unprognostic (7.23e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (7.74e-2)" "prognostic favorable (9.45e-4)" "unprognostic (7.18e-2)" "unprognostic (3.46e-1)" "unprognostic (4.94e-3)" "unprognostic (1.92e-2)" 14.3 9.2 4.4 15.6 6.9 19.6 13.9 7.1 6.9 14.3 4.6 20.1 11.1 14.6 6.5 12.7 9.8 11.3 10.4 4.7 6.6 18.1 19.3 13.7 11.9 8.9 7.0 7.8 11.4 18.5 3.4 13.2 8.2 7.0 21.9 6.4 8.3 8.8 11.7 4.5 13.1 21.1 7.8 8.7 9.9 16.3 6.3 16.1 12.6 12.6 12.8 14.6 5.2 11.9 43.1 36.3 23.3 19.0 32.2 33.2 33.3 29.6 21.9 34.5 34.8 70.6 34.0 58.5 59.5 45.0 46.3 47.5 64.4 45.1 47.8 51.4 16.7 77.6 56.5 75.8 31.9 82.3 63.5 28.6 28.7 58.6 44.6 33.3 75.3 42.1 44.9 26.3 45.7 0.1 59.9 22.4 33.3 42.7 30.9 47.0 65.1 32.7 60.0 65.0 22.0 31.3 66.2 5.8 43.0 58.1 0.4 35.4 70.0 29.4 61.9 26.8 64.2 28.7 59.0 23.6 29.4 43.1 11.8 2.6 3.3 5.8 1.9 4.0 2.9 1.7 3.0 2.4 3.6 1.1 2.7 1.6 1.5 2.8 3.6 0.1 4.3 2.2 4.4 6.9 7.1 6.9 4.7 6.6 8.9 7.0 8.2 7.8 6.3 11.9 20.2 16.0 13.1 29.4 10.7 10.8 6.5 15.5 12.0 11.5 19.2 6.7 20.0 20.0 13.0 14.7 2.1 14.1 15.5 25.6 13.7 20.9 262.2 25.2 17.2 14.0 19.8 20.8 53.0 23.2 20.6 23.0 18.8 25.4 64.1 16.6 11.7 31.0 31.8 15.2 61.7 30.4 16.2 30.0 31.8 41.4 14.6 28.7 14.2 56.2 36.0 12.0 21.6 45.8 83.8 23.9 17.4 13.9 14.1 3.8 15.3 46.5 21.6 7.6 6.6 16.8 16.4 41.7 22.2 16.2 9.8 7.0 19.0 22.7 26.0 6.1 TTC30B "fleer, FLJ30990, IFT70B" ENSG00000196659 "Tetratricopeptide repeat domain 30B" Q8N4P2 2 177548998-177552796 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 43.3;Spermatocytes: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA051714, HPA052100, HPA052487" Supported Approved Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Centrosome "HPA051714: AB_2681583, HPA052100: AB_2681726, HPA052487: AB_2681848" "unprognostic (5.76e-2)" "unprognostic (5.29e-2)" "unprognostic (2.15e-2)" "unprognostic (9.10e-2)" "unprognostic (1.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.89e-2)" "unprognostic (3.26e-1)" "unprognostic (5.45e-2)" "unprognostic (2.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (5.27e-2)" "unprognostic (9.77e-2)" "unprognostic (9.61e-2)" "unprognostic (9.25e-3)" "unprognostic (1.65e-1)" 1.7 1.6 1.7 1.8 1.8 0.8 5.3 1.8 1.8 3.4 3.3 3.3 2.6 3.3 6.8 2.0 10.3 2.1 1.7 1.6 1.7 4.9 2.5 3.2 2.2 2.3 2.6 3.4 2.4 5.1 1.6 1.7 2.1 2.8 3.0 5.2 3.7 3.2 0.4 2.4 2.9 2.5 2.5 2.3 3.9 7.0 2.0 3.2 8.2 0.5 2.4 1.9 0.8 2.6 2.5 3.7 4.7 0.9 4.1 4.8 3.2 1.4 4.5 3.9 4.1 2.1 6.1 0.9 3.9 2.8 4.5 6.0 5.7 6.2 3.7 1.4 2.8 1.7 2.2 1.8 3.5 2.2 2.9 4.0 5.7 3.8 2.9 4.7 3.1 4.5 2.3 0.8 2.3 4.2 4.4 3.4 2.2 3.3 0.9 3.4 4.1 1.0 5.9 2.7 11.4 6.2 1.8 4.1 2.9 6.4 4.2 4.2 2.7 2.1 1.1 2.8 1.2 2.1 2.6 0.3 4.9 0.9 3.7 2.7 1.4 1.2 0.6 1.3 0.4 0.5 0.4 0.7 1.6 1.4 0.8 0.8 0.8 0.9 1.0 1.1 0.4 0.7 1.7 1.8 1.8 1.8 1.6 1.7 2.3 2.6 2.1 2.5 2.0 2.6 1.8 3.2 4.6 1.3 2.8 0.6 0.6 5.0 2.8 2.2 3.1 2.8 1.4 5.7 7.9 0.0 2.1 2.5 0.4 4.8 5.9 4.8 10.8 12.8 3.7 2.5 1.2 1.3 0.7 2.7 1.1 3.3 5.1 1.9 1.3 3.2 2.5 2.8 1.2 5.0 0.8 2.4 6.1 1.3 0.6 6.6 1.5 1.3 1.8 1.9 1.4 7.2 4.1 1.5 1.1 2.6 0.5 2.2 4.1 0.6 2.6 5.3 43.3 11.5 0.0 2.7 1.8 24.5 3.7 2.3 0.9 0.5 1.3 5.4 1.8 0.2 TTC30A "FAP259, FLJ13946, IFT70A" ENSG00000197557 "Tetratricopeptide repeat domain 30A" Q86WT1 2 177612999-177618742 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 50.1;Respiratory ciliated cells: 29.0;Spermatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA051714, HPA052100, HPA052487" Supported Approved Nucleoplasm,Centrosome NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Centrosome" "HPA051714: AB_2681583, HPA052100: AB_2681726, HPA052487: AB_2681848" "unprognostic (7.75e-2)" "unprognostic (3.83e-3)" "unprognostic (2.16e-1)" "unprognostic (3.00e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-2)" "unprognostic (1.24e-1)" "unprognostic (3.79e-1)" "unprognostic (4.10e-2)" "unprognostic (1.58e-1)" "unprognostic (1.10e-1)" "unprognostic (1.78e-2)" "unprognostic (1.85e-1)" "unprognostic (5.84e-3)" "unprognostic (1.41e-1)" "unprognostic (4.67e-3)" "unprognostic (6.07e-2)" 2.1 1.8 1.9 1.2 2.1 0.4 4.2 1.9 1.9 2.9 4.0 2.6 1.7 3.2 7.9 1.6 6.3 2.2 3.4 1.8 2.2 5.0 2.9 2.5 1.2 2.4 2.6 2.5 3.3 5.6 2.1 0.9 2.6 2.9 2.5 8.2 3.2 2.8 1.5 1.1 1.7 2.7 2.6 1.2 2.8 9.9 2.2 1.7 7.2 1.2 1.3 1.2 0.6 2.6 5.1 2.9 2.8 0.0 5.7 4.7 2.1 2.4 7.1 4.3 4.5 0.9 3.6 1.1 4.6 4.3 5.8 4.2 1.9 5.4 4.7 0.3 1.6 1.0 1.4 1.3 2.3 1.2 1.1 2.9 3.5 2.4 0.9 4.1 2.0 2.5 0.7 0.5 3.0 2.6 4.0 2.4 1.6 1.8 1.0 2.5 7.5 0.5 5.4 1.3 9.2 6.2 2.2 4.2 2.6 6.6 2.4 1.3 1.8 2.6 1.5 2.9 2.0 1.9 1.9 0.3 6.6 0.1 2.6 0.0 0.3 0.4 0.0 0.4 0.0 0.0 0.0 0.1 0.3 0.1 0.5 0.2 0.1 0.0 0.3 0.1 0.2 0.2 1.9 2.1 1.9 1.9 1.8 2.2 2.4 2.6 2.6 2.6 2.2 2.6 2.3 9.6 3.1 1.6 1.2 0.8 0.8 3.6 1.8 3.0 3.8 2.4 3.6 2.8 4.7 7.3 2.1 1.0 0.4 5.0 1.9 5.5 50.1 10.8 3.1 2.0 7.2 0.4 1.2 4.0 0.7 3.2 1.5 1.6 0.0 2.8 3.6 3.8 0.8 16.8 1.6 2.5 8.2 0.6 0.4 10.9 2.1 0.8 1.8 0.0 0.3 10.6 0.0 0.5 1.0 2.9 1.0 2.2 1.2 1.1 1.7 4.7 29.0 11.7 0.0 4.1 2.1 51.7 4.3 2.8 0.4 0.3 0.9 4.1 1.9 0.3 PDE11A ENSG00000128655 "Phosphodiesterase 11A" Q9HCR9 2 177623244-178072777 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Hydrolase" "Cushing syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 6.3;parathyroid gland: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0;Hepatocytes: 11.1;Late spermatids: 46.4;Oligodendrocytes: 14.9" "Cancer enhanced" "Detected in some" "prostate cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.6;fHDF/TERT166: 2.4;HAP1: 1.4;Hep G2: 2.8" HPA034560 Approved "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA034560: AB_10602140" "unprognostic (1.02e-1)" "unprognostic (4.73e-2)" "unprognostic (1.02e-1)" "unprognostic (9.61e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.23e-1)" "unprognostic (3.91e-1)" "unprognostic (9.95e-2)" "unprognostic (2.80e-2)" "unprognostic (5.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.11e-4)" "unprognostic (1.64e-3)" 2.3 0.3 0.8 0.1 2.0 0.2 1.7 1.9 1.2 0.6 0.6 0.5 0.8 1.2 0.4 0.0 0.3 0.4 0.3 0.6 2.1 0.5 6.3 0.0 0.0 2.5 2.1 0.4 1.1 9.8 0.9 0.0 2.7 5.2 0.4 1.4 1.4 0.8 4.4 0.1 0.5 1.1 3.7 0.1 0.4 2.8 1.9 0.1 1.3 1.3 0.0 0.0 0.1 3.2 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.2 1.6 0.0 0.6 2.4 0.3 0.1 1.4 0.0 0.0 0.0 0.9 1.1 0.1 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.2 0.2 0.4 0.1 0.6 0.0 0.3 0.2 0.0 0.2 0.0 0.5 0.0 0.3 0.7 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.8 2.0 1.9 1.2 0.6 2.1 2.5 2.1 2.7 3.7 1.9 3.2 0.1 0.0 0.0 2.3 0.2 0.6 1.4 0.1 0.0 1.7 4.2 0.8 0.0 1.5 0.1 0.0 0.0 0.1 0.3 0.8 0.0 0.8 37.0 0.3 0.2 0.6 6.7 2.7 1.6 6.7 0.0 0.6 0.0 0.2 0.0 0.0 1.4 11.1 0.1 0.0 8.2 0.9 6.1 1.2 2.1 46.4 1.5 0.3 0.0 0.0 0.0 4.7 0.0 6.0 14.9 2.3 0.0 0.7 0.0 5.4 0.6 1.3 0.1 1.0 0.0 2.0 0.6 6.8 6.9 0.0 1.3 0.3 0.3 0.3 1.3 1.0 PDE11A ENSG00000284741 "Phosphodiesterase 11A" 2 177628069-178108339 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 9 "Cardiomyocytes: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA034560 Uncertain NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA034560: AB_10602140" 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RBM45 "DRB1, FLJ44612" ENSG00000155636 "RNA binding motif protein 45" Q8IUH3 2 178112424-178139011 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020448 Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA020448: AB_1856133" "unprognostic (3.11e-2)" "unprognostic (1.91e-1)" "unprognostic (6.56e-2)" "unprognostic (2.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (5.74e-9)" "unprognostic (1.66e-1)" "unprognostic (4.25e-2)" "unprognostic (2.71e-2)" "unprognostic (2.42e-1)" "unprognostic (5.79e-2)" "prognostic unfavorable (5.34e-9)" "unprognostic (3.26e-1)" "unprognostic (2.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.94e-1)" 4.8 6.5 12.5 5.5 12.9 4.1 8.5 12.4 18.4 5.6 12.7 8.3 5.9 6.3 9.2 6.1 7.3 4.7 6.4 12.6 12.9 6.5 8.1 5.4 8.1 12.9 12.5 5.7 7.9 8.8 6.4 3.3 12.8 5.8 9.3 9.8 6.2 5.2 4.8 8.2 6.7 5.7 12.6 7.8 6.5 6.6 12.6 8.9 7.0 3.2 9.9 5.6 5.1 13.3 9.5 10.1 15.7 6.5 13.6 15.7 9.8 12.8 14.5 12.9 14.2 10.7 7.7 15.8 8.4 15.3 12.9 8.4 13.1 16.7 15.7 12.7 11.2 12.2 6.3 16.1 14.3 14.9 11.6 12.7 13.7 13.2 11.0 12.5 13.7 8.7 11.5 12.6 16.2 15.1 15.5 10.0 11.1 14.2 12.8 12.4 11.1 15.7 19.0 21.8 9.7 10.1 9.0 8.8 11.8 17.7 12.9 13.9 11.7 9.1 8.6 10.7 12.7 11.7 14.4 20.3 8.9 11.9 12.8 3.8 5.3 1.9 6.2 8.6 7.1 12.5 6.5 6.8 7.2 8.6 5.9 7.3 1.0 11.3 10.2 7.7 10.9 5.3 12.5 12.9 12.4 18.4 12.6 12.9 12.9 12.5 12.8 12.6 12.6 13.3 5.2 3.2 4.2 8.5 6.3 2.5 3.5 11.3 5.2 7.1 4.3 3.6 4.2 8.6 6.6 1.8 10.4 5.6 8.1 5.0 7.9 7.3 3.8 4.8 5.4 5.9 6.0 8.6 10.2 6.6 10.3 5.7 7.7 3.5 8.2 8.2 3.3 5.1 8.2 10.1 13.1 7.6 4.1 8.1 3.3 4.3 4.4 5.3 1.8 6.5 8.1 7.6 6.2 15.1 13.7 5.2 6.5 5.7 8.0 1.7 6.1 7.0 9.6 9.1 6.6 6.1 6.1 11.4 5.6 6.2 3.4 1.8 6.2 9.1 4.9 2.7 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 PRKRA "DYT16, HSD14, PACT, RAX" ENSG00000180228 "Protein activator of interferon induced protein kinase EIF2AK2" O75569 2 178431292-178451512 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, RNA-mediated gene silencing" RNA-binding "Disease variant, Dystonia, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004648, HPA034996, HPA034997" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "CAB004648: AB_425767, HPA034996: AB_2674402, HPA034997: AB_2674403" "unprognostic (2.53e-1)" "unprognostic (9.18e-2)" "unprognostic (5.38e-2)" "unprognostic (4.02e-3)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (8.33e-5)" "unprognostic (9.66e-2)" "unprognostic (7.10e-3)" "unprognostic (2.32e-3)" "unprognostic (4.79e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-3)" "unprognostic (8.99e-2)" "prognostic favorable (5.45e-4)" "unprognostic (1.38e-1)" "unprognostic (6.78e-2)" 28.7 21.9 22.1 13.8 22.6 18.2 26.4 24.6 31.3 23.6 25.3 36.4 13.7 28.7 25.7 22.8 23.4 17.5 37.2 22.8 24.9 29.7 20.2 21.2 16.9 25.0 22.5 23.4 25.4 26.2 22.5 11.5 24.2 23.4 20.1 30.9 22.6 24.3 100.7 31.2 19.7 29.4 25.2 15.9 26.0 24.3 23.1 20.4 22.1 72.7 20.4 32.1 22.0 27.1 24.6 18.4 48.2 20.8 49.2 56.7 39.6 35.4 37.7 46.4 50.8 50.9 33.8 51.0 39.8 43.6 30.9 21.0 42.0 28.5 50.9 43.9 25.0 29.2 17.0 46.7 58.6 21.2 16.1 32.2 69.3 44.0 49.7 46.0 46.8 32.8 26.7 34.9 62.9 25.3 46.3 52.2 46.7 42.3 33.5 38.5 89.0 46.6 52.4 25.5 30.2 39.4 21.9 20.2 48.3 36.3 30.6 27.4 20.8 32.0 42.6 33.8 29.9 52.5 33.7 62.6 40.8 35.1 20.7 5.4 24.7 25.9 18.1 25.5 26.2 34.3 28.4 22.7 37.2 26.4 31.4 25.8 5.1 25.2 26.3 49.7 38.3 30.9 22.1 22.6 24.6 31.3 22.8 24.9 25.0 22.5 24.2 25.2 23.1 27.1 35.1 16.0 33.4 23.2 37.7 63.1 90.0 89.3 30.1 53.6 48.1 40.3 43.5 20.0 39.9 25.8 43.8 37.7 49.3 16.9 125.2 51.4 149.5 43.6 36.2 34.5 47.9 19.1 39.5 41.6 53.2 42.7 19.4 27.0 28.5 40.5 21.8 18.5 30.4 10.1 46.4 35.5 93.6 19.8 69.4 307.9 39.4 26.4 69.4 21.5 38.6 49.2 9.2 30.7 47.1 36.0 25.1 37.2 42.5 94.7 30.8 89.0 30.6 86.2 46.0 45.6 66.7 78.7 57.6 43.7 78.4 43.4 33.6 47.0 39.6 73.0 PJVK DFNB59 ENSG00000204311 Pejvakin Q0ZLH3 2 178451346-178462102 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 9.1;Distal tubular cells: 3.9;Granulosa cells: 6.1;Theca cells: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.8" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "SuSa: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042621 Approved Mitochondria No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA042621: AB_10797503" "unprognostic (4.01e-2)" "unprognostic (4.28e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-1)" "unprognostic (7.21e-3)" "unprognostic (9.36e-2)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" "unprognostic (8.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.90e-3)" "unprognostic (9.13e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (2.41e-2)" "unprognostic (8.06e-3)" 3.0 1.8 6.9 1.3 7.2 1.4 4.8 6.9 10.7 2.7 6.9 1.9 1.2 3.9 7.3 1.2 2.8 2.9 1.4 7.0 7.0 3.2 2.8 1.5 1.9 7.6 7.3 7.1 1.3 1.1 4.1 1.2 7.5 2.8 1.2 6.4 2.7 3.0 3.5 4.2 1.4 2.0 7.3 1.4 1.2 20.7 7.1 1.2 2.5 0.9 1.7 1.9 1.4 7.7 0.2 1.8 2.3 1.9 3.0 3.1 1.2 1.5 1.4 1.2 2.0 0.7 3.1 2.1 1.5 0.9 1.0 0.9 1.7 1.0 0.9 0.7 0.6 0.7 2.9 0.4 3.0 0.6 0.2 3.2 2.2 1.4 3.2 3.8 1.5 4.1 0.4 1.3 1.5 0.5 2.1 1.3 2.8 0.2 0.8 2.7 1.7 1.3 2.0 1.0 1.6 1.3 0.5 0.3 0.6 6.8 0.7 0.7 1.0 1.5 0.6 0.4 0.1 4.3 2.8 0.7 0.7 1.1 0.6 0.1 0.1 0.0 0.1 0.1 0.2 0.3 0.2 0.1 0.0 0.5 0.5 0.3 0.4 0.2 0.0 2.8 0.0 0.0 6.9 7.2 6.9 10.7 7.0 7.0 7.6 7.3 7.5 7.3 7.1 7.7 1.6 6.4 9.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 2.4 0.0 0.0 1.8 1.8 0.0 1.1 0.5 0.0 3.9 1.4 0.0 1.8 2.6 0.4 0.0 0.0 0.0 0.9 0.5 1.4 0.0 1.6 0.0 6.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 4.7 0.0 0.0 FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 50.0" "Cell type enhanced" "Detected in many" "Early spermatids: 149.1;Endometrial stromal cells: 54.8;Fibroblasts: 67.6;Leydig cells: 64.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 155.0;ASC TERT1: 96.7;fHDF/TERT166: 60.9;HSkMC: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA008707: AB_1848624" "unprognostic (1.33e-1)" "unprognostic (1.89e-2)" "unprognostic (1.43e-1)" "unprognostic (1.67e-1)" "unprognostic (5.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.34e-2)" "unprognostic (1.83e-2)" "unprognostic (6.05e-2)" "unprognostic (8.96e-3)" "prognostic unfavorable (4.61e-6)" "unprognostic (3.50e-3)" "unprognostic (1.34e-2)" "unprognostic (4.19e-3)" "unprognostic (1.10e-1)" 9.3 5.4 1.5 3.9 1.6 1.4 11.9 2.6 2.8 23.1 1.5 8.3 2.8 27.8 11.3 5.9 15.1 15.4 12.3 1.6 1.8 5.2 8.3 7.8 2.9 1.6 1.5 50.0 2.8 2.7 5.0 13.0 1.5 9.3 6.2 2.1 5.0 13.3 3.8 4.2 4.4 19.2 1.2 3.0 5.4 4.4 1.5 2.5 6.6 6.5 2.8 11.6 10.2 2.1 0.2 1.9 18.5 27.8 155.0 96.7 1.7 33.3 55.0 5.9 19.0 0.3 1.9 5.4 7.3 60.9 5.5 0.3 7.1 2.8 10.3 4.5 3.9 5.7 7.3 5.5 23.7 3.5 3.8 64.7 1.4 24.0 3.4 44.2 19.8 6.6 2.5 3.4 25.2 0.3 6.1 6.0 3.6 3.5 2.9 7.8 31.9 7.7 8.4 0.6 9.7 32.0 7.0 0.2 6.2 12.7 0.5 6.8 18.2 11.0 6.8 12.8 3.2 6.3 7.2 2.6 19.9 8.7 24.3 0.0 0.4 0.0 1.0 0.7 1.2 1.1 0.9 0.7 2.6 0.7 0.9 1.0 0.0 0.6 0.0 2.1 1.1 0.4 1.5 1.6 2.6 2.8 1.6 1.8 1.6 1.5 1.5 1.2 1.5 2.1 16.2 6.4 4.1 2.9 5.4 7.0 9.3 19.6 7.4 4.2 6.7 13.6 16.1 2.8 5.2 7.3 0.0 7.6 2.7 0.7 1.9 10.9 149.1 3.4 54.8 19.3 1.2 4.2 1.6 8.4 22.4 67.6 4.1 3.5 14.0 19.0 15.7 11.9 5.8 5.0 3.7 5.6 14.2 4.4 13.6 27.1 64.0 3.8 17.8 4.7 1.6 4.2 1.0 7.1 4.2 3.9 0.7 48.5 10.3 3.4 0.4 3.7 2.1 3.6 6.6 31.1 37.7 8.5 5.1 3.7 5.8 5.1 5.5 30.4 3.1 4.1 PLEKHA3 FAPP1 ENSG00000116095 "Pleckstrin homology domain containing A3" Q9HB20 2 178480457-178516463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 196.2;Late spermatids: 413.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034496, HPA034497" Approved Enhanced "Golgi apparatus" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA034496: AB_2674189, HPA034497: AB_10603126" "unprognostic (1.24e-1)" "unprognostic (2.33e-2)" "unprognostic (5.93e-2)" "unprognostic (3.74e-2)" "unprognostic (1.71e-1)" "unprognostic (1.97e-1)" "unprognostic (3.22e-3)" "unprognostic (8.83e-2)" "unprognostic (4.02e-2)" "unprognostic (8.23e-3)" "unprognostic (2.96e-2)" "unprognostic (3.10e-1)" "unprognostic (2.34e-1)" "unprognostic (2.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.51e-2)" "unprognostic (8.52e-2)" 3.6 6.6 4.1 3.9 4.7 5.4 3.0 7.1 5.9 3.4 5.9 4.0 4.6 3.5 6.2 3.2 3.5 3.0 6.3 4.2 4.2 4.7 4.1 3.2 3.6 3.8 4.2 3.8 2.7 4.6 4.2 2.7 4.1 3.6 2.6 8.0 2.7 4.3 2.7 1.7 3.4 3.4 4.0 3.4 3.9 10.0 4.3 1.3 3.7 3.2 2.8 3.7 2.5 5.1 4.1 2.7 3.1 4.0 6.0 3.2 5.9 6.6 5.0 3.2 3.5 1.1 2.7 3.5 8.3 4.7 9.0 2.8 2.9 1.7 6.0 10.8 2.8 5.5 2.7 3.2 4.2 3.5 6.0 2.9 5.6 5.9 3.7 5.7 2.9 3.1 2.6 5.4 4.3 1.3 4.7 5.1 5.2 2.9 3.9 2.5 4.6 6.1 4.1 2.4 3.2 4.5 3.3 2.4 10.4 4.3 2.8 6.1 3.3 6.3 6.1 8.0 7.4 6.7 14.2 3.5 8.2 2.9 3.7 0.5 0.2 0.3 0.4 0.2 0.4 0.5 0.7 0.5 0.2 1.5 0.4 0.5 0.6 0.8 0.4 0.6 0.3 0.1 4.1 4.7 7.1 5.9 4.2 4.2 3.8 4.2 4.1 4.0 4.3 5.1 56.7 16.0 14.6 9.8 32.7 43.2 48.4 12.6 50.7 90.3 39.6 35.2 56.1 32.9 13.4 27.6 41.7 29.2 53.6 15.3 78.2 36.9 196.2 44.9 39.5 44.9 25.8 35.3 15.8 47.3 18.6 43.0 21.4 38.0 10.8 23.7 39.3 42.8 15.8 132.9 20.4 23.3 12.2 28.3 44.9 413.6 34.8 33.1 30.2 18.7 28.6 56.7 40.2 11.6 18.5 45.0 11.3 52.3 39.9 91.7 20.0 67.9 17.9 64.0 78.9 54.2 54.4 66.0 41.5 28.6 30.4 30.5 44.0 44.8 19.0 79.7 TTN "CMD1G, CMH9, CMPD4, FLJ32040, LGMD2J, MYLK5, TMD" ENSG00000155657 Titin Q8WZ42 2 178525989-178830802 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 167.2;skeletal muscle: 920.6;tongue: 369.5" "Cell type enriched" "Detected in many" 16 "Cardiomyocytes: 24394.9" "Cancer enriched" "Detected in single" 4 "head and neck cancer: 1.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "RH-30: 1.9" "Not detected" "Not detected" "HPA007042, CAB022682, HPA030048" Enhanced NA NA 16000000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB022682: , HPA007042: AB_1080292, HPA030048: AB_2732451" "unprognostic (1.00e-2)" "unprognostic (3.92e-1)" "unprognostic (1.77e-1)" "unprognostic (7.11e-2)" "unprognostic (3.71e-2)" "unprognostic (1.49e-2)" "unprognostic (6.62e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (2.79e-1)" "unprognostic (2.65e-1)" "unprognostic (3.49e-4)" "unprognostic (1.99e-1)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" 0.6 0.4 2.7 0.5 2.4 4.3 0.5 2.8 4.9 0.3 0.0 0.4 0.4 0.4 0.2 2.7 0.3 0.7 167.2 1.9 3.4 0.2 0.3 1.2 1.4 11.2 4.4 0.7 1.7 0.0 0.8 0.5 6.6 2.7 0.0 1.9 7.0 0.0 920.6 0.8 0.6 0.0 3.2 0.7 0.4 1.6 4.8 0.7 0.6 369.5 0.4 0.2 0.3 5.3 0.3 0.1 0.7 0.4 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.7 0.1 1.0 0.2 0.0 0.7 0.7 0.0 0.0 0.0 1.0 0.8 1.5 1.3 0.4 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.7 0.6 0.7 0.9 0.5 0.1 0.2 0.7 1.0 0.2 0.1 0.7 0.5 1.9 0.6 0.0 0.2 0.4 0.7 0.1 0.5 0.0 0.6 0.3 1.0 0.7 0.0 0.0 0.3 0.2 1.4 0.2 1.4 0.0 0.5 0.3 1.8 0.2 0.5 0.4 0.2 0.1 6.1 0.9 0.7 0.1 5.7 2.0 2.6 1.0 3.6 0.2 0.2 6.0 0.1 2.7 2.4 2.8 4.9 1.9 3.4 11.2 4.4 6.6 3.2 4.8 5.3 10.9 16.0 173.4 43.8 32.1 0.9 1.6 0.0 2.8 102.7 1.7 0.5 24394.9 30.0 6.2 0.0 20.9 0.7 6.8 0.1 1.9 14.1 43.2 3.4 6.8 99.1 4.2 3.0 25.1 28.3 0.3 502.5 3.6 7.2 10.1 0.7 2.5 0.6 0.3 16.8 31.3 0.1 0.0 0.8 0.8 6.4 1.2 26.2 0.0 25.3 0.6 12.0 2.1 11.6 4.9 0.5 0.1 4.5 10.6 0.2 0.3 0.4 2.9 27.8 0.0 1466.9 104.7 9.3 1.5 2.3 0.1 0.4 24.3 2.8 0.5 0.1 CCDC141 "CAMDI, FLJ39502" ENSG00000163492 "Coiled-coil domain containing 141" Q6ZP82 2 178829757-179050086 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 74.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 29.5;Bipolar cells: 28.1;Cardiomyocytes: 118.2;Cholangiocytes: 27.1;Early spermatids: 37.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 15.0" "Group enriched" "Detected in many" 9 "B-cells: 8.1;T-cells: 15.0" "Cell line enhanced" "Detected in some" "CACO-2: 4.6;Daudi: 3.0;HEL: 6.9;RH-30: 3.6;U-266/70: 4.3;U-698: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012718 Approved Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "HPA012718: AB_2072055" "unprognostic (1.58e-1)" "unprognostic (1.85e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-1)" "unprognostic (8.62e-3)" "unprognostic (4.25e-2)" "unprognostic (2.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.40e-1)" "unprognostic (1.74e-2)" "unprognostic (5.33e-2)" "unprognostic (8.03e-3)" "unprognostic (7.71e-8)" "unprognostic (2.50e-2)" "unprognostic (1.52e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-1)" 1.5 0.3 0.8 0.5 0.4 1.3 0.7 0.9 1.0 0.6 0.8 0.2 0.1 0.6 0.2 0.4 0.4 1.7 74.6 0.3 0.6 0.1 0.3 2.0 1.5 1.2 1.1 1.0 5.8 0.1 0.0 1.2 1.4 0.3 0.2 1.1 0.1 0.2 17.1 0.5 0.2 0.2 1.6 0.7 0.2 1.5 1.0 1.5 0.3 3.5 1.1 0.3 0.1 1.8 0.1 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.1 4.6 0.3 3.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 2.6 0.1 6.9 0.2 0.0 0.0 1.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.1 0.2 2.4 0.4 0.5 0.1 3.6 1.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.7 0.2 0.3 0.0 0.2 0.1 0.2 0.0 4.3 0.1 6.1 0.2 0.3 0.4 0.4 0.0 0.2 0.3 0.0 0.2 7.3 2.2 1.5 0.0 8.1 6.5 5.1 0.3 1.2 0.0 0.0 15.0 0.4 0.8 0.4 0.9 1.0 0.3 0.6 1.2 1.1 1.4 1.6 1.0 1.8 4.5 6.4 29.5 5.5 11.0 0.1 0.0 0.0 0.6 28.1 0.2 0.3 118.2 27.1 0.6 0.0 0.0 0.0 2.8 0.1 0.0 4.6 37.3 0.2 1.1 6.7 0.0 0.4 3.6 1.3 0.2 2.9 0.0 1.1 6.3 0.0 0.4 0.3 0.0 6.7 3.1 0.1 0.0 1.0 1.0 16.8 1.2 3.9 1.8 8.4 0.1 5.5 1.0 0.5 0.8 0.2 0.0 1.9 2.6 0.0 0.2 0.1 1.5 0.6 6.6 2.8 5.4 0.1 1.1 0.0 0.1 0.0 10.3 1.1 0.2 0.2 SESTD1 "DKFZp434O0515, Solo" ENSG00000187231 "SEC14 and spectrin domain containing 1" Q86VW0 2 179101678-179264832 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 175.5;Horizontal cells: 301.2;Oligodendrocytes: 311.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058236, HPA077408" Approved Enhanced "Intermediate filaments" NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Intermediate filaments" "HPA058236: AB_2732619, HPA077408: AB_2732344" "unprognostic (2.76e-1)" "unprognostic (3.55e-2)" "unprognostic (2.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (9.47e-2)" "unprognostic (1.64e-1)" "unprognostic (2.59e-1)" "unprognostic (7.91e-3)" "unprognostic (9.21e-2)" "prognostic favorable (2.78e-11)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.57e-2)" 15.4 2.4 11.6 3.2 17.2 4.7 11.2 12.5 11.4 6.2 0.9 7.1 2.0 5.8 3.9 4.5 4.5 6.4 6.3 8.2 10.3 6.7 3.4 9.2 3.4 16.2 13.5 4.5 3.3 3.9 3.6 6.8 14.6 4.2 3.8 7.5 11.0 4.6 3.6 4.5 5.4 8.1 15.1 3.5 5.5 9.0 18.1 2.9 3.7 5.8 4.9 10.0 4.8 23.6 0.0 2.1 25.5 4.6 45.2 19.5 13.5 9.0 3.7 3.7 6.3 4.6 6.0 4.5 11.7 8.7 4.5 4.2 11.0 5.1 6.8 3.3 2.9 5.5 11.2 12.3 3.5 3.1 2.3 14.6 2.1 5.7 14.3 8.9 15.2 4.6 0.8 2.3 6.4 3.1 7.2 0.3 6.6 4.7 2.6 10.3 16.8 2.9 10.0 23.2 5.6 9.5 8.0 3.4 2.5 18.7 0.5 3.4 26.7 12.3 6.2 6.3 4.7 1.3 0.0 11.0 6.2 1.2 3.7 0.0 0.9 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.4 1.5 0.0 0.0 0.1 0.3 1.6 0.0 0.0 0.2 11.6 17.2 12.5 11.4 8.2 10.3 16.2 13.5 14.6 15.1 18.1 23.6 46.2 109.0 29.9 53.2 30.6 9.8 24.7 19.1 7.4 31.3 30.4 15.6 15.3 28.6 32.9 12.9 18.8 10.7 5.7 11.9 17.6 31.3 9.8 61.3 33.1 32.1 25.0 7.2 110.8 27.7 73.4 65.1 13.7 175.5 0.0 23.1 21.4 9.6 12.3 301.2 147.9 7.3 14.2 28.7 43.4 7.3 12.2 37.2 14.2 89.0 21.9 33.4 5.2 86.5 311.1 33.3 13.3 30.5 4.7 67.7 22.5 39.1 42.8 10.4 19.7 43.7 29.2 34.9 66.0 10.2 10.1 18.1 5.7 9.8 9.7 119.9 ZNF385B "FLJ25270, ZNF533" ENSG00000144331 "Zinc finger protein 385B" Q569K4 2 179441982-179861612 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 88.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 124.2;Bipolar cells: 220.1;Excitatory neurons: 566.5;Inhibitory neurons: 393.1;Rod photoreceptor cells: 133.7" "Cancer enhanced" "Detected in many" "prostate cancer: 6.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 17.6;HAP1: 31.9;U-698: 91.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046086 Approved "Nucleoli fibrillar center" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center" "HPA046086: AB_2679532" "prognostic favorable (4.86e-8)" "unprognostic (8.05e-3)" "unprognostic (1.14e-1)" "unprognostic (3.91e-2)" "unprognostic (3.49e-1)" "unprognostic (1.51e-2)" "unprognostic (3.49e-3)" "unprognostic (1.14e-1)" "unprognostic (8.99e-3)" "unprognostic (3.56e-2)" "unprognostic (4.59e-2)" "unprognostic (2.69e-1)" "prognostic favorable (1.04e-9)" "unprognostic (7.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.35e-2)" "unprognostic (1.20e-3)" 2.3 5.2 4.1 0.3 25.4 0.4 6.9 27.3 17.4 1.6 0.0 2.4 0.3 1.5 3.8 1.1 1.1 0.7 24.1 6.9 1.9 8.5 19.1 18.4 1.6 9.6 3.0 15.2 0.3 0.0 1.0 2.2 10.8 12.6 0.7 88.7 1.2 0.5 17.1 1.6 0.8 0.4 0.0 0.5 14.2 10.3 6.8 0.5 1.2 10.9 0.6 1.5 2.2 9.5 0.0 0.0 7.3 0.3 0.1 0.3 0.1 0.0 0.0 0.4 0.8 0.0 0.0 17.6 0.1 0.0 5.9 0.0 31.9 0.0 0.4 0.0 4.3 0.2 0.7 1.2 0.0 0.0 0.0 3.6 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.3 0.1 0.1 1.3 0.0 2.0 0.0 1.3 1.3 1.8 0.0 0.7 0.2 0.0 0.0 0.0 0.7 0.5 0.0 0.0 0.3 2.3 0.3 1.5 0.0 0.0 91.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 25.4 27.3 17.4 6.9 1.9 9.6 3.0 10.8 0.0 6.8 9.5 1.0 28.9 124.2 12.1 0.0 3.4 0.7 0.0 0.0 220.1 5.1 2.2 32.4 5.7 1.3 0.0 54.2 0.0 0.0 0.3 82.2 0.0 58.4 1.0 0.1 0.5 1.8 0.0 566.5 0.0 0.0 6.4 3.1 1.7 1.3 19.6 1.4 14.3 0.3 1.7 393.1 0.0 0.0 0.0 0.3 29.2 0.6 0.5 1.8 89.0 0.0 6.4 0.0 20.1 10.7 0.1 0.0 0.4 0.1 4.9 0.0 24.5 1.5 133.7 0.0 5.2 1.6 6.2 1.8 0.1 0.9 0.1 0.3 3.3 0.1 0.9 CWC22 "EIF4GL, fSAPb, KIAA1604, NCM" ENSG00000163510 "CWC22 spliceosome associated protein homolog" Q9HCG8 2 179944876-180007297 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036748 Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" Cytosol "HPA036748: AB_10669913" "unprognostic (1.90e-1)" "unprognostic (7.10e-2)" "unprognostic (7.30e-2)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (4.33e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (3.15e-1)" "unprognostic (1.31e-2)" "unprognostic (3.30e-2)" "unprognostic (3.84e-2)" "unprognostic (4.80e-2)" "prognostic unfavorable (7.76e-5)" "unprognostic (1.74e-1)" "unprognostic (3.03e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-3)" 12.7 10.2 7.1 13.1 7.8 16.0 15.0 13.5 10.1 14.1 7.1 11.9 10.1 16.9 10.4 12.5 12.0 12.1 10.1 7.6 7.2 13.4 16.8 11.5 18.5 6.4 6.9 19.3 9.2 13.5 8.2 14.5 7.0 12.5 11.8 12.4 10.2 10.9 13.6 11.0 10.4 13.9 7.1 14.7 11.0 9.0 7.0 21.8 16.0 14.5 18.2 14.1 12.1 8.9 19.1 11.2 31.6 21.1 22.7 26.7 24.1 24.5 28.7 29.4 28.7 25.9 23.1 36.7 21.6 17.9 25.6 20.5 30.4 23.1 44.2 33.0 26.2 49.1 15.1 35.4 22.0 69.6 26.2 17.5 27.1 37.4 49.8 19.3 22.3 25.2 54.6 21.9 19.7 18.9 36.5 34.7 48.8 22.5 18.3 32.8 38.9 27.7 20.2 23.5 21.6 28.8 20.3 15.9 28.5 33.8 11.8 42.2 19.0 25.1 21.2 16.8 25.7 19.2 21.5 44.3 22.6 27.2 26.1 49.7 13.3 31.4 16.1 16.7 16.3 17.4 17.3 19.5 13.9 14.5 21.1 16.7 22.0 16.0 13.3 8.6 16.5 11.5 7.1 7.8 13.5 10.1 7.6 7.2 6.4 6.9 7.0 7.1 7.0 8.9 38.0 19.2 33.8 20.5 38.0 19.1 29.2 16.9 22.2 19.5 12.9 19.8 26.6 22.8 27.0 11.0 25.0 18.3 36.5 11.8 9.8 23.4 1.6 24.2 31.9 27.2 15.6 14.9 35.8 19.1 17.5 32.5 19.9 25.1 27.3 24.7 16.8 12.8 13.7 13.5 28.4 16.4 14.2 20.6 12.1 2.4 23.3 24.2 3.6 15.0 31.6 17.3 30.9 35.2 35.1 18.7 17.6 18.4 20.8 16.8 15.7 20.3 34.4 19.1 46.0 40.3 25.1 22.8 21.3 14.1 18.6 24.8 32.5 18.6 15.6 19.5 UBE2E3 UbcH9 ENSG00000170035 "Ubiquitin conjugating enzyme E2 E3" Q969T4 2 180967248-181076585 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 654.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003303, HPA030445" Approved NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" "HPA003303: AB_1858521, HPA030445: AB_10669599" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-1)" "unprognostic (2.96e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (8.08e-5)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.00e-3)" "unprognostic (4.99e-2)" "unprognostic (8.46e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (8.75e-2)" "unprognostic (3.86e-1)" "unprognostic (2.50e-1)" "unprognostic (1.28e-1)" "unprognostic (2.18e-1)" "unprognostic (4.40e-1)" 61.6 45.8 57.8 40.1 60.8 48.3 58.1 59.9 71.5 56.2 51.4 51.4 46.7 51.6 55.8 46.7 58.3 71.4 54.2 74.3 59.7 71.8 58.3 39.9 39.6 56.6 57.8 52.5 56.5 79.4 35.3 48.6 58.0 40.0 54.4 68.4 54.6 39.6 175.1 57.0 42.5 42.9 62.3 40.3 59.2 56.8 58.8 67.9 73.7 88.6 48.4 61.6 46.9 64.1 104.8 46.6 654.4 22.8 189.8 243.1 104.0 137.1 171.9 112.8 139.2 51.0 124.0 51.4 117.1 188.5 94.5 43.8 400.7 140.5 202.1 125.9 120.3 177.2 59.0 142.5 91.6 83.5 81.3 96.7 127.9 99.3 94.8 114.6 150.9 105.4 91.9 93.3 280.7 57.5 152.6 77.7 125.6 71.2 217.6 147.0 66.8 122.1 193.2 91.1 113.4 126.3 59.7 62.8 58.1 178.3 33.7 121.5 140.1 218.2 143.2 129.4 162.0 81.1 55.0 143.7 215.7 32.6 124.3 29.1 28.2 53.7 17.6 25.4 21.3 15.0 13.6 22.7 18.4 9.5 14.3 15.7 25.6 18.5 36.3 60.0 5.9 20.5 57.8 60.8 59.9 71.5 74.3 59.7 56.6 57.8 58.0 62.3 58.8 64.1 69.3 9.6 24.2 100.9 50.3 102.9 83.7 111.2 70.6 151.8 84.4 74.4 37.7 108.7 63.7 55.2 29.2 31.9 84.8 56.4 229.0 95.8 36.9 54.3 51.6 59.8 59.8 108.8 115.4 101.9 83.4 81.2 60.6 57.8 23.5 61.8 72.1 55.9 85.3 75.7 67.7 39.4 91.6 71.4 63.9 79.7 62.7 76.3 129.9 71.2 62.4 103.9 79.3 160.9 158.3 113.7 41.6 36.1 87.7 74.8 58.9 172.6 51.8 73.3 26.3 56.4 81.7 83.1 191.6 77.3 122.3 36.0 55.4 57.9 50.9 103.4 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 CERKL RP26 ENSG00000188452 "Ceramide kinase like" Q49MI3 2 181536672-181680665 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17.1;retina: 16.6" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.8;Endometrial ciliated cells: 43.5;Proximal tubular cells: 13.4;Respiratory ciliated cells: 38.7;Rod photoreceptor cells: 22.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 9.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 28 "SCLC-21H: 58.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 14.5" "HPA035443, HPA035444, HPA043203" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "HPA035443: AB_2674625, HPA035444: AB_10672093, HPA043203: " "unprognostic (7.52e-3)" "unprognostic (6.13e-3)" "unprognostic (2.09e-1)" "unprognostic (3.92e-3)" "unprognostic (4.46e-1)" "unprognostic (2.71e-3)" "unprognostic (2.59e-1)" "unprognostic (1.39e-2)" "unprognostic (2.76e-1)" "unprognostic (2.27e-1)" "prognostic favorable (5.25e-4)" "unprognostic (4.54e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.37e-1)" "unprognostic (3.65e-2)" "unprognostic (3.07e-2)" "unprognostic (8.45e-2)" 1.2 0.5 0.3 0.2 0.6 0.0 1.0 9.7 0.4 3.1 6.0 2.3 0.2 0.8 0.3 0.5 7.8 0.7 0.5 0.8 0.6 8.0 1.3 5.1 0.9 1.8 2.0 0.3 0.7 0.6 0.7 0.1 1.8 1.0 0.3 16.6 1.0 0.2 0.4 0.4 6.8 0.2 1.8 17.1 1.2 0.5 0.4 0.4 0.9 0.3 1.9 1.3 1.2 1.8 0.0 0.8 0.0 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.4 0.0 0.3 0.2 0.0 0.3 2.0 0.0 0.4 0.3 0.4 0.0 0.0 0.6 0.5 0.1 0.3 0.6 0.0 0.5 0.9 0.3 0.7 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.8 0.4 0.0 0.4 1.2 0.0 0.0 0.9 0.0 58.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.1 1.1 0.8 0.0 0.0 0.3 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.6 9.7 0.4 0.8 0.6 1.8 2.0 1.8 1.8 0.4 1.8 0.0 3.2 0.5 0.3 0.0 0.0 0.1 1.0 0.0 0.5 0.0 0.0 0.7 1.5 4.9 0.0 18.8 0.0 1.5 0.0 9.8 0.0 4.6 43.5 0.7 0.3 1.8 0.0 6.8 0.0 0.1 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 2.0 0.0 0.0 2.8 0.0 0.3 0.0 0.0 0.1 2.5 0.0 0.5 0.2 0.0 0.0 0.0 0.4 0.0 2.7 13.4 38.7 22.8 0.0 0.2 0.5 0.4 0.9 0.0 0.0 0.0 0.6 0.0 1.2 0.0 NEUROD1 "BETA2, BHF-1, bHLHa3, MODY6, NEUROD" ENSG00000162992 "Neuronal differentiation 1" Q13562 2 181673088-181680547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 61.4;retina: 125.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 77.5;Cone photoreceptor cells: 150.1;Enteroendocrine cells: 424.2;Rod photoreceptor cells: 203.7" "Group enriched" "Detected in some" 4 "glioma: 1.9;pancreatic cancer: 4.3" "Region enriched" "Detected in many" 7 "cerebellum: 61.4" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 74 "SCLC-21H: 321.5" "Region enriched" "Detected in all" 14 "cerebellum: 216.2" "Region enriched" "Detected in many" 19 "cerebellum: 217.0" "HPA003278, CAB022450" Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "CAB022450: , HPA003278: AB_1845331" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" "unprognostic (6.92e-3)" "unprognostic (1.27e-1)" 0.0 0.1 3.0 0.1 2.1 0.1 0.0 61.4 7.2 0.0 0.7 1.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.7 0.0 0.0 0.0 0.0 0.9 2.4 0.0 10.2 0.0 0.7 0.0 5.2 0.0 1.4 125.7 0.0 0.0 0.1 0.0 4.7 0.0 0.9 0.0 5.4 0.2 0.8 0.2 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 321.5 4.3 0.0 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.3 0.3 0.4 0.2 0.2 0.1 3.0 2.1 61.4 7.2 9.2 0.7 0.9 2.4 5.2 0.9 0.8 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 77.5 0.0 0.0 0.5 0.0 0.0 0.0 150.1 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.9 424.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.1 23.8 0.0 0.3 0.0 0.6 0.0 0.1 0.0 0.0 0.0 25.9 0.0 0.0 0.1 1.7 12.6 0.0 0.0 0.2 0.7 0.1 0.0 203.7 0.0 0.3 0.0 1.0 0.1 0.0 0.0 0.0 0.3 0.0 1.4 0.2 ITPRID2 "CS-1, KIAA1927, KRAP, SPAG13, SSFA2" ENSG00000138434 "ITPR interacting domain containing 2" P28290 2 181891730-181930738 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 175.8" "Cell type enhanced" "Detected in some" "Adipocytes: 30.7;Cardiomyocytes: 30.0;Cytotrophoblasts: 25.7;Extravillous trophoblasts: 26.8;Hofbauer cells: 20.4;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 6.1;monocytes: 5.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034665, HPA039989" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" Nucleoplasm "HPA034665: AB_2674271, HPA039989: AB_2676788" "unprognostic (1.68e-1)" "unprognostic (3.27e-2)" "unprognostic (2.17e-2)" "unprognostic (4.70e-2)" "unprognostic (8.77e-2)" "unprognostic (8.87e-2)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (5.63e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.95e-2)" "prognostic favorable (2.91e-5)" "unprognostic (3.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (5.79e-5)" 30.8 20.7 55.0 20.6 62.9 42.4 32.1 57.2 66.2 30.9 50.3 50.4 36.4 25.8 18.4 22.8 20.3 37.7 24.4 45.5 61.5 48.4 79.3 44.9 17.6 65.2 60.5 13.6 175.8 20.9 18.3 34.7 63.3 34.0 44.2 16.9 69.9 17.1 31.9 112.9 34.0 25.6 57.3 32.4 56.1 37.4 62.6 24.1 36.5 23.4 16.0 31.3 29.5 61.1 56.0 25.8 71.6 12.6 53.8 41.3 21.7 94.6 82.6 29.1 37.0 25.9 56.0 1.2 30.7 59.7 31.5 46.2 14.5 41.6 56.6 25.2 20.3 52.5 106.6 23.5 45.7 28.5 48.9 30.0 64.4 51.3 57.7 66.7 145.8 22.3 25.0 29.5 82.9 28.7 25.4 41.0 5.0 47.0 62.5 18.7 29.3 19.2 87.0 16.3 13.7 12.1 55.7 19.7 91.0 27.6 14.2 61.6 68.1 73.1 37.0 27.5 50.3 20.9 9.4 21.9 34.0 17.1 57.2 6.1 2.8 4.2 0.9 2.7 0.6 0.4 0.6 0.6 2.7 0.9 0.8 0.7 4.7 0.8 5.1 2.1 0.4 1.3 55.0 62.9 57.2 66.2 45.5 61.5 65.2 60.5 63.3 57.3 62.6 61.1 30.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 25.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 26.8 7.7 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 33.4 1.1 0.0 0.0 0.0 PPP1R1C Inhibitor-1-like ENSG00000150722 "Protein phosphatase 1 regulatory inhibitor subunit 1C" Q8WVI7 2 181954241-182131398 "Predicted intracellular proteins" "Cell cycle, Cell division" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 21.1" "Group enriched" "Detected in many" 4 "Early spermatids: 168.5;Late spermatids: 219.8;Spermatocytes: 145.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055043 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Golgi apparatus" "HPA055043: AB_2797251" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (4.54e-3)" "unprognostic (1.08e-2)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (2.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.57e-2)" "unprognostic (6.59e-3)" "unprognostic (1.13e-1)" "unprognostic (7.98e-2)" "unprognostic (3.70e-2)" "unprognostic (1.00e-3)" "unprognostic (7.68e-2)" "unprognostic (3.07e-2)" "unprognostic (9.75e-3)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 21.1 0.3 1.0 0.0 0.8 0.1 0.0 0.7 0.8 0.0 0.3 0.0 0.4 0.0 1.4 1.0 0.0 1.8 0.0 0.0 3.7 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.1 0.7 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.4 0.4 0.3 1.0 0.7 0.8 1.4 0.1 0.1 0.3 0.1 12.8 8.7 6.2 0.0 0.3 0.6 1.2 2.8 1.1 0.3 0.3 40.6 17.2 8.1 3.7 0.0 3.1 0.0 0.5 1.9 2.5 168.5 1.7 0.1 0.6 6.1 0.0 1.1 11.0 6.6 2.4 4.6 0.8 0.0 0.0 0.0 18.5 0.6 0.0 19.4 0.4 10.2 0.8 0.0 219.8 5.9 0.3 3.6 1.9 3.6 12.0 0.0 3.5 0.7 23.1 0.1 0.7 0.0 0.3 0.0 0.7 1.6 1.7 0.0 0.4 0.8 145.1 2.6 1.3 0.3 2.5 0.0 0.8 0.6 1.0 PDE1A ENSG00000115252 "Phosphodiesterase 1A" P54750 2 182140036-182523192 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.6;thyroid gland: 45.8" "Cell type enhanced" "Detected in many" "Early spermatids: 396.3;Excitatory neurons: 764.9;Late spermatids: 592.1;Oligodendrocytes: 1178.0" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC diff: 37.2;HHSteC: 22.0;HSkMC: 47.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022151 Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA022151: AB_1855118" "unprognostic (3.63e-1)" "unprognostic (7.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.61e-2)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (3.84e-1)" "unprognostic (3.82e-1)" "unprognostic (1.02e-1)" "unprognostic (5.38e-2)" "unprognostic (2.78e-1)" "unprognostic (2.86e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-3)" "unprognostic (5.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.40e-3)" 10.5 4.4 16.9 4.6 20.4 0.0 5.0 35.5 23.4 17.2 2.4 11.8 3.0 8.7 8.0 5.6 10.3 23.7 15.6 30.3 8.4 46.6 3.9 3.6 2.1 2.6 4.2 10.9 2.1 2.2 2.7 1.2 5.4 3.6 6.7 1.4 2.0 5.4 2.8 2.2 5.7 12.9 3.7 3.1 5.6 35.6 16.5 8.4 45.8 5.0 0.9 9.7 9.8 18.2 0.0 0.2 3.9 0.0 37.2 3.1 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 4.7 0.0 5.1 0.0 22.0 0.0 0.0 47.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.5 1.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.7 0.0 5.4 0.1 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 20.4 35.5 23.4 30.3 8.4 2.6 4.2 5.4 3.7 16.5 18.2 6.7 0.0 2.6 15.3 0.0 1.3 2.0 0.1 8.0 20.0 0.3 0.3 5.9 1.5 1.4 27.6 0.0 0.1 0.0 0.1 185.9 0.5 396.3 0.3 0.4 8.9 0.0 0.0 764.9 0.4 0.0 18.6 0.0 0.8 0.0 0.1 5.0 0.0 0.1 0.0 185.8 1.0 0.0 0.0 1.8 592.1 14.9 0.4 0.0 30.0 0.0 0.3 0.0 18.1 1178.0 0.2 0.1 8.2 0.2 2.6 0.1 1.5 0.0 1.2 52.6 21.0 45.1 9.1 4.9 1.0 1.3 0.0 0.2 7.6 0.1 0.7 DNAJC10 "ERdj5, PDIA19" ENSG00000077232 "DnaJ heat shock protein family (Hsp40) member C10" Q8IXB1 2 182716255-182794464 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 113.9" "Cell type enhanced" "Detected in all" "Early spermatids: 219.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031111 Approved NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "HPA031111: AB_10601211" "unprognostic (3.29e-2)" "unprognostic (5.20e-3)" "unprognostic (3.10e-3)" "prognostic favorable (6.42e-5)" "unprognostic (1.89e-1)" "unprognostic (1.18e-1)" "unprognostic (4.34e-3)" "unprognostic (1.82e-2)" "unprognostic (1.54e-2)" "unprognostic (4.34e-2)" "unprognostic (2.29e-1)" "unprognostic (9.76e-2)" "prognostic unfavorable (2.19e-7)" "unprognostic (2.91e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (7.27e-4)" "unprognostic (2.87e-2)" 21.2 15.0 5.5 30.1 6.4 8.4 22.5 5.9 6.3 29.0 7.7 20.5 19.4 40.4 113.9 13.6 30.2 27.3 18.2 6.5 10.0 19.7 15.0 18.5 32.4 7.9 7.4 24.6 33.0 28.5 20.2 24.6 7.6 24.0 28.0 15.6 24.1 28.9 9.2 8.3 20.3 28.0 7.1 26.1 35.2 38.9 6.6 18.7 37.0 10.8 40.1 22.6 12.3 9.5 25.6 29.0 42.8 28.5 60.2 72.7 45.4 49.6 85.5 34.9 49.4 43.6 65.9 126.0 50.0 58.0 53.1 29.4 26.5 47.4 64.4 44.5 22.4 23.5 35.1 43.9 55.6 68.0 51.4 41.3 57.3 47.3 109.0 70.1 87.7 23.9 32.3 52.4 41.1 16.4 21.0 10.8 48.5 46.3 46.0 28.6 31.7 114.9 48.2 38.4 30.6 33.1 35.1 42.6 28.5 69.9 21.0 21.9 79.6 70.8 44.9 36.0 39.8 32.5 51.0 45.2 83.0 43.7 58.5 1.7 12.3 0.9 5.5 10.6 7.2 22.4 5.8 6.5 15.7 16.7 4.7 5.7 0.9 7.2 9.8 5.9 4.8 9.3 5.5 6.4 5.9 6.3 6.5 10.0 7.9 7.4 7.6 7.1 6.6 9.5 49.6 44.8 22.0 34.3 79.9 17.2 21.1 18.8 18.2 36.0 38.6 27.8 44.1 34.3 39.5 57.0 18.8 11.7 22.9 12.5 5.9 45.3 219.8 103.0 61.5 51.9 32.4 23.4 46.2 61.9 41.5 49.4 43.8 115.5 30.9 46.0 34.6 23.4 38.7 23.5 38.3 117.3 40.7 29.3 29.1 55.1 36.4 40.6 19.6 48.7 41.2 22.8 27.8 37.7 47.2 44.0 19.9 44.4 67.9 38.8 6.8 19.4 132.0 30.5 46.0 40.2 53.8 112.6 41.7 20.6 14.8 10.8 28.8 32.8 21.5 18.6 FRZB "FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, hFIZ, SFRP3, SRFP3" ENSG00000162998 "Frizzled related protein" Q92765 2 182833275-182866637 "Disease related genes, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 336.9" "Cell type enriched" "Detected in many" 13 "Muller glia cells: 3633.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.2;ASC diff: 9.4;NTERA-2: 7.4;SH-SY5Y: 6.5" "Region enhanced" "Detected in all" "olfactory bulb: 56.9" "Low region specificity" "Detected in all" "Secreted in other tissues" NA NA 44000 "Cluster 19: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.39e-2)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" "unprognostic (1.79e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-3)" "unprognostic (1.64e-2)" "unprognostic (2.38e-2)" "unprognostic (4.67e-2)" "unprognostic (8.58e-2)" "unprognostic (5.41e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (8.97e-6)" "unprognostic (3.53e-2)" "unprognostic (1.05e-2)" "unprognostic (6.04e-2)" "unprognostic (3.21e-1)" 10.4 5.7 10.4 6.1 12.8 0.7 12.6 11.0 18.6 20.3 52.2 16.2 14.4 17.2 11.4 12.4 7.1 39.0 19.9 10.3 11.2 16.3 3.3 9.1 18.7 14.1 10.9 13.5 7.1 6.7 18.6 30.5 15.4 12.9 19.9 336.9 4.7 16.6 26.6 10.4 14.5 31.1 11.9 88.9 21.9 14.2 11.3 4.9 10.8 116.2 11.9 10.3 12.3 10.3 0.0 0.0 19.2 0.2 9.4 0.2 0.2 0.0 0.9 3.2 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.8 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 7.4 0.0 0.0 0.6 0.8 0.0 0.0 0.0 1.0 6.5 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 12.8 11.0 18.6 10.3 11.2 14.1 10.9 15.4 11.9 11.3 10.3 13.8 0.0 0.5 1.0 0.8 8.2 0.4 0.2 0.6 39.8 7.8 18.7 2.9 0.0 1.4 0.0 33.3 5.3 0.5 2.1 0.0 0.1 0.3 0.5 1.4 18.5 1.2 0.0 2.7 8.2 3.8 97.8 9.7 0.9 0.0 0.5 3.6 1.0 7.8 26.9 7.7 137.4 0.0 0.8 3.7 2.8 3.7 0.5 245.5 25.3 0.0 3633.8 0.0 8.5 1.7 0.2 0.8 14.7 5.8 1.8 1.3 0.2 0.2 124.4 276.1 41.9 157.1 0.2 0.1 0.6 3.1 12.4 1.5 22.9 3.4 0.6 NCKAP1 "HEM2, Nap1, NAP125" ENSG00000061676 "NCK associated protein 1" Q9Y2A7 2 182909115-183038858 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020449 Enhanced Approved Cytosol NA NA 60000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "HPA020449: AB_1854327" "unprognostic (7.92e-3)" "unprognostic (1.24e-2)" "unprognostic (3.35e-2)" "unprognostic (8.10e-2)" "unprognostic (1.31e-1)" "unprognostic (1.24e-1)" "unprognostic (2.12e-3)" "prognostic unfavorable (9.71e-4)" "unprognostic (5.06e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (3.48e-2)" "unprognostic (1.92e-1)" "unprognostic (3.44e-2)" "unprognostic (2.41e-1)" "unprognostic (1.36e-1)" "unprognostic (3.61e-2)" 51.5 44.3 48.3 25.6 57.6 1.0 48.7 45.9 58.7 55.0 43.5 59.4 55.9 52.8 52.9 81.3 42.1 42.3 71.8 72.8 47.2 70.6 41.2 40.3 10.3 36.9 46.2 45.0 43.0 88.4 34.0 50.1 41.9 55.4 48.5 58.4 43.2 65.4 89.5 51.1 51.3 74.1 37.9 20.5 57.7 32.1 45.4 15.2 85.4 87.3 24.6 60.8 49.1 44.4 107.1 66.0 99.1 63.6 136.8 132.3 110.2 136.5 123.4 90.6 113.3 102.9 89.2 0.6 89.2 163.1 136.1 99.0 84.6 128.6 150.2 25.7 66.1 23.7 69.4 85.4 140.5 0.2 19.9 99.5 155.4 131.4 213.8 123.7 146.3 6.4 58.7 0.4 173.3 68.5 2.3 0.4 102.1 85.8 112.7 6.9 108.2 0.4 127.9 141.9 72.7 69.3 123.6 97.0 130.0 156.2 52.0 0.7 160.0 153.2 86.1 87.1 84.7 13.4 26.5 0.5 118.6 0.1 79.5 0.4 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 48.3 57.6 45.9 58.7 72.8 47.2 36.9 46.2 41.9 37.9 45.4 44.4 75.3 48.1 47.1 129.9 2.1 87.2 64.7 50.1 38.1 83.9 54.2 39.9 103.9 48.6 57.0 80.9 70.9 33.1 3.7 52.4 27.4 54.3 4.5 56.4 57.9 82.8 50.4 0.8 174.2 62.0 50.2 62.3 49.5 106.6 14.0 43.8 72.8 42.4 5.3 122.8 143.9 58.8 50.8 5.5 23.1 9.0 78.6 4.6 55.2 72.1 0.7 90.7 6.2 136.7 98.8 95.7 69.8 105.3 1.4 116.8 64.3 66.4 40.2 59.9 59.2 86.1 84.1 42.4 28.7 83.6 112.5 52.1 5.5 55.6 55.5 117.3 DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100008 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 15.2;Endometrial ciliated cells: 17.7;Respiratory ciliated cells: 15.7;Spermatocytes: 15.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "amygdala: 1.3;basal ganglia: 2.4;cerebral cortex: 2.7;hippocampal formation: 3.8" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 7.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021501 Approved Approved Nucleoplasm Yes No "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA021501: AB_1847892" "unprognostic (1.24e-1)" "unprognostic (2.13e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (5.18e-2)" "unprognostic (2.44e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-1)" "unprognostic (8.30e-2)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (6.53e-2)" "unprognostic (5.80e-3)" "unprognostic (6.97e-2)" "unprognostic (2.91e-2)" "unprognostic (2.16e-2)" "unprognostic (2.75e-2)" 1.1 1.4 1.3 0.8 2.4 0.3 1.1 0.0 2.7 1.2 0.1 1.4 1.4 1.4 3.5 1.4 3.2 1.3 3.1 3.8 0.1 1.8 1.1 1.3 1.0 0.1 0.0 1.6 0.9 1.6 1.2 1.0 0.0 1.5 1.0 1.2 0.9 1.9 1.6 1.3 1.1 1.9 0.0 1.6 3.9 3.7 0.0 1.2 1.7 1.7 0.7 1.1 0.6 0.4 0.1 1.6 1.8 0.9 2.5 1.4 0.0 0.7 1.1 2.9 1.0 1.5 1.9 0.6 3.8 0.8 2.1 0.2 3.8 0.5 2.3 3.9 1.8 7.1 1.1 1.0 1.0 1.8 4.2 1.1 0.3 1.3 0.7 1.8 1.5 0.0 2.2 1.0 1.8 0.6 3.4 1.6 1.5 0.6 1.2 3.3 2.9 0.2 0.6 0.7 2.3 0.9 2.6 1.1 2.0 0.1 0.5 0.6 1.3 1.6 1.3 1.1 0.6 1.3 1.6 0.0 2.0 0.3 2.4 0.7 0.1 0.6 0.6 0.2 0.6 1.1 0.5 0.8 0.1 0.5 0.7 0.7 0.3 0.7 0.1 0.4 1.0 0.3 1.3 2.4 0.0 2.7 3.8 0.1 0.1 0.0 0.0 0.0 0.0 0.4 2.5 0.0 3.2 0.7 1.6 1.0 1.3 1.1 3.4 1.8 2.1 2.7 8.3 1.5 1.8 1.8 2.1 2.0 0.8 1.5 5.9 0.9 15.2 17.7 2.3 3.3 2.4 0.0 9.9 0.7 1.5 1.7 3.6 1.5 1.3 3.0 2.9 1.9 0.6 1.7 7.8 1.9 0.0 0.8 0.3 6.0 1.8 2.2 0.0 1.0 1.1 4.8 2.1 4.0 3.1 0.6 3.4 2.6 0.3 0.7 2.2 2.9 15.7 1.5 0.0 1.9 4.4 15.5 3.8 2.3 1.6 0.7 1.2 3.6 1.8 1.1 NUP35 MP44 ENSG00000163002 "Nucleoporin 35" Q8NFH5 2 183117513-183161680 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 151.6;Late spermatids: 424.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018401, HPA018410, HPA018441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Plasma membrane" "HPA018401: AB_1854719, HPA018410: AB_1854721, HPA018441: AB_1854720" "unprognostic (6.18e-3)" "unprognostic (3.15e-1)" "unprognostic (1.83e-1)" "unprognostic (3.58e-3)" "unprognostic (1.37e-1)" "unprognostic (9.91e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.95e-1)" "unprognostic (6.21e-3)" "prognostic favorable (3.45e-4)" "unprognostic (2.32e-2)" "unprognostic (1.61e-3)" "unprognostic (1.78e-3)" "unprognostic (6.78e-2)" "unprognostic (3.47e-2)" "unprognostic (1.24e-1)" "unprognostic (3.96e-2)" 7.7 8.9 5.9 6.9 7.3 4.6 13.1 8.9 7.8 8.5 5.0 7.6 6.3 8.1 7.7 8.7 8.9 6.9 6.2 6.1 5.9 10.2 14.4 5.9 9.1 5.5 5.9 10.4 10.2 8.9 6.3 7.8 5.5 7.8 9.1 9.0 8.4 7.0 7.4 9.0 6.5 8.9 6.6 5.7 7.2 24.2 5.5 10.4 8.2 8.7 11.0 9.2 8.0 6.4 19.7 19.7 32.5 20.5 11.8 11.5 23.2 23.0 18.8 35.3 33.5 37.6 24.7 34.6 22.0 12.4 40.9 17.4 45.4 26.7 57.8 29.6 27.8 32.6 16.4 43.9 8.2 23.6 21.8 8.2 13.8 29.9 28.9 7.9 20.8 20.5 28.7 25.3 27.8 23.7 28.7 29.1 57.9 31.6 61.9 34.3 25.2 25.0 34.0 24.7 29.4 20.3 21.6 26.6 26.0 24.4 17.0 16.2 10.6 28.6 19.7 23.3 26.5 16.4 38.3 37.9 19.3 16.8 39.2 0.0 4.1 1.4 4.9 5.5 8.6 7.2 6.3 6.0 3.2 6.5 7.5 6.7 0.2 5.6 6.6 3.1 6.7 4.1 5.9 7.3 8.9 7.8 6.1 5.9 5.5 5.9 5.5 6.6 5.5 6.4 9.6 9.6 6.8 6.5 10.3 26.0 20.7 17.5 12.5 10.8 9.3 8.9 4.7 14.3 13.8 16.5 18.8 23.6 8.5 3.3 11.7 15.5 151.6 5.3 8.1 10.2 3.6 12.6 11.5 12.7 20.2 10.8 5.1 6.4 8.2 8.1 12.8 12.6 8.4 6.7 12.0 7.5 16.2 4.4 9.9 424.7 9.6 3.6 21.4 2.8 5.0 11.4 7.2 17.1 12.8 11.1 5.1 8.2 7.5 12.8 4.2 14.5 6.9 19.1 13.1 18.7 11.6 39.8 21.1 11.3 27.4 9.4 11.5 9.0 9.6 11.2 ZNF804A C2orf10 ENSG00000170396 "Zinc finger protein 804A" Q7Z570 2 184598529-184939492 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;retina: 3.8" "Group enriched" "Detected in many" 9 "Excitatory neurons: 267.9;Inhibitory neurons: 676.0;Oligodendrocyte precursor cells: 186.5" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 28.3;RH-30: 17.7;THP-1: 13.9;U-698: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029195 Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 6: Brain - Smell perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA029195: AB_10603011" "unprognostic (1.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.05e-2)" "unprognostic (1.08e-2)" "unprognostic (1.26e-2)" "unprognostic (1.50e-1)" "unprognostic (2.41e-1)" "unprognostic (4.45e-1)" "unprognostic (2.38e-2)" "unprognostic (2.83e-2)" "unprognostic (5.20e-2)" "unprognostic (4.98e-4)" "unprognostic (6.21e-2)" "unprognostic (4.04e-1)" "unprognostic (8.45e-2)" "unprognostic (4.93e-2)" 0.0 0.2 1.6 1.0 4.7 0.6 0.0 4.7 5.0 0.1 0.0 0.2 0.5 0.0 0.0 0.1 0.0 1.1 0.0 3.3 3.5 0.6 0.1 0.3 0.9 2.1 0.8 0.2 0.0 0.0 0.0 0.1 1.6 1.2 0.3 3.8 0.1 1.3 0.0 0.0 1.2 0.1 0.5 0.6 0.4 0.2 1.8 0.0 1.4 0.0 1.0 0.4 0.0 0.6 0.0 0.0 1.5 0.0 0.0 0.0 0.0 2.9 6.3 2.1 1.9 0.0 0.0 28.3 0.0 0.0 2.6 0.0 0.4 0.0 4.6 0.2 0.0 7.4 1.0 0.1 10.0 7.1 0.0 3.1 0.0 0.0 1.6 3.2 4.9 0.0 0.0 1.2 0.0 0.0 0.0 6.8 0.0 0.0 4.8 0.0 17.7 1.1 0.0 0.0 0.4 3.1 0.0 0.0 0.0 0.1 0.0 13.9 0.0 6.8 0.1 0.2 2.8 3.1 0.0 20.5 7.7 2.0 2.2 0.0 0.2 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.6 4.7 4.7 5.0 3.3 3.5 2.1 0.8 1.6 0.5 1.8 0.6 0.1 0.0 0.6 13.4 9.2 0.0 0.0 0.0 0.0 38.0 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.2 2.2 0.6 0.0 5.5 267.9 0.0 0.0 2.2 0.0 0.3 0.0 0.9 0.0 0.2 2.9 3.3 676.0 1.1 0.0 1.6 3.7 0.6 0.3 5.4 0.0 6.5 3.5 1.0 0.0 186.5 5.4 0.0 0.0 0.0 21.5 0.0 1.5 0.1 0.0 2.9 6.6 0.1 0.7 5.3 1.2 0.0 0.0 0.0 0.5 1.1 2.7 0.1 FSIP2 FLJ34780 ENSG00000188738 "Fibrous sheath interacting protein 2" Q5CZC0 2 185738804-185833290 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 18.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 137.8;Alveolar cells type 2: 93.8;Early spermatids: 289.6;Gastric mucus-secreting cells: 68.3;Spermatocytes: 124.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RT4: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA036139 Approved Microtubules,Mitochondria NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Microtubules Mitochondria "HPA036139: AB_10602134" "unprognostic (5.28e-2)" "unprognostic (1.20e-2)" "unprognostic (4.17e-1)" "unprognostic (5.81e-2)" "unprognostic (1.67e-1)" "unprognostic (2.95e-1)" "unprognostic (6.31e-2)" "unprognostic (2.76e-3)" "unprognostic (1.55e-1)" "unprognostic (5.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.79e-3)" "unprognostic (4.89e-3)" "unprognostic (1.28e-1)" "unprognostic (7.52e-2)" "unprognostic (5.17e-2)" "unprognostic (4.64e-5)" 0.1 0.2 0.3 0.2 0.5 0.0 0.2 0.3 0.3 0.2 0.0 1.5 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.5 0.4 0.2 0.2 0.2 0.4 0.1 0.6 0.2 0.9 0.6 0.2 0.0 0.0 0.2 0.2 0.0 0.6 0.0 2.6 18.3 0.3 0.1 0.2 0.0 0.0 0.2 0.1 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.3 0.2 0.3 0.5 0.4 0.6 0.6 0.3 0.9 1.7 137.8 93.8 5.2 2.6 0.5 0.1 1.4 1.8 16.3 3.0 1.7 3.9 0.0 31.5 0.0 10.4 0.3 1.0 26.0 0.0 0.7 289.6 3.3 3.3 5.6 7.7 0.0 4.5 0.2 0.1 7.3 68.3 2.1 40.4 2.7 1.8 0.1 0.4 18.5 5.4 19.7 0.0 0.8 1.0 50.8 2.1 5.9 1.8 3.7 0.7 3.9 2.1 23.6 14.0 5.4 5.5 3.8 1.3 0.2 0.5 0.2 46.0 7.2 0.0 4.0 0.8 124.4 5.4 0.2 0.3 0.3 6.0 2.6 5.2 0.2 ZC3H15 LEREPO4 ENSG00000065548 "Zinc finger CCCH-type containing 15" Q8WU90 2 186486253-186509361 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031099, HPA031100, HPA031101" Enhanced Enhanced Cytosol NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "HPA031099: AB_10599418, HPA031100: AB_2257403, HPA031101: AB_10611669" "unprognostic (1.51e-1)" "prognostic unfavorable (6.45e-5)" "unprognostic (2.24e-1)" "unprognostic (3.11e-3)" "unprognostic (5.92e-2)" "unprognostic (8.15e-2)" "prognostic unfavorable (1.48e-7)" "unprognostic (9.08e-3)" "unprognostic (4.95e-2)" "prognostic favorable (3.98e-4)" "prognostic unfavorable (9.75e-4)" "unprognostic (5.72e-3)" "unprognostic (5.69e-2)" "unprognostic (1.87e-1)" "unprognostic (1.82e-1)" "unprognostic (8.89e-2)" "unprognostic (3.45e-2)" 42.6 47.5 39.2 44.3 42.0 128.8 45.9 43.4 52.5 35.1 38.6 40.8 48.3 39.8 47.0 40.2 26.3 36.5 37.0 42.6 44.5 53.8 67.3 28.4 53.9 42.2 40.9 32.6 47.9 41.2 27.2 48.8 41.7 37.0 46.0 53.0 45.3 32.4 50.3 44.3 46.1 36.9 39.4 38.6 36.8 40.6 41.7 50.2 49.3 44.9 51.4 54.0 29.2 42.4 103.5 68.9 83.3 107.8 93.0 93.4 124.9 112.7 76.7 102.3 91.5 202.9 81.8 140.3 100.2 80.9 130.9 73.6 155.8 137.5 144.0 128.7 118.1 201.9 101.1 221.9 124.9 208.7 118.6 77.2 149.6 111.4 157.2 89.9 111.9 86.0 197.0 106.8 108.4 93.5 133.7 146.5 157.6 135.7 171.8 105.2 113.0 131.6 127.6 124.0 100.3 73.6 71.5 96.4 167.3 124.3 68.1 149.7 95.7 114.7 99.1 70.9 136.4 92.0 167.0 199.8 101.7 145.7 102.3 59.9 47.9 49.1 44.7 61.6 55.8 55.0 54.8 57.4 54.7 42.2 50.5 53.9 28.8 60.4 75.1 48.0 66.6 41.5 39.2 42.0 43.4 52.5 42.6 44.5 42.2 40.9 41.7 39.4 41.7 42.4 107.1 73.7 83.6 26.4 137.0 212.2 169.1 116.6 99.6 75.0 101.9 118.9 95.8 57.2 104.8 115.8 60.5 131.3 116.1 131.4 256.3 112.0 153.1 110.1 125.5 106.4 101.7 98.7 38.0 104.3 167.0 107.4 67.8 127.1 112.2 220.1 62.4 137.0 124.3 57.2 39.8 136.1 87.5 107.4 104.8 307.1 78.6 113.2 64.0 33.7 142.5 82.6 126.7 19.6 32.8 111.6 106.2 87.3 128.0 179.5 164.1 330.2 68.3 130.2 32.9 156.2 127.6 215.6 174.4 116.1 209.1 177.6 117.3 319.6 151.2 163.5 ITGAV "CD51, MSK8, VNRA, VTNR" ENSG00000138448 "Integrin subunit alpha V" P06756 2 186590056-186680901 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "RT4: 369.7;SuSa: 297.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002499, HPA004856" Supported Approved "Focal adhesion sites,Cytosol" NA NA 2000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Focal adhesion sites, Cytosol" "CAB002499: AB_563594, HPA004856: AB_1846316" "unprognostic (4.03e-2)" "unprognostic (5.17e-3)" "unprognostic (1.22e-2)" "unprognostic (5.22e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (1.48e-2)" "unprognostic (6.95e-2)" "unprognostic (2.89e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (5.84e-2)" "unprognostic (2.67e-2)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.61e-1)" "unprognostic (9.11e-2)" "unprognostic (8.07e-2)" 39.9 38.7 20.1 36.5 30.8 6.4 27.7 39.7 23.5 39.7 40.3 20.1 15.9 36.8 10.5 24.5 26.3 47.3 80.0 18.2 32.7 52.1 18.0 25.7 15.8 42.5 33.0 64.7 25.7 82.7 11.9 47.4 46.4 29.8 21.6 80.4 32.1 28.1 16.3 41.4 16.3 56.7 45.3 21.4 34.2 14.7 30.2 18.0 62.6 30.5 21.6 43.1 16.0 54.6 49.1 57.5 37.4 119.9 134.1 90.0 141.7 93.8 75.5 32.5 32.5 50.7 164.0 0.4 179.7 106.3 113.4 60.2 19.3 88.5 46.7 9.7 17.2 11.7 69.1 69.6 52.8 8.3 7.0 65.8 41.3 72.7 61.1 194.1 78.7 5.9 11.6 23.9 87.4 19.4 5.0 6.8 28.3 29.1 28.5 0.1 76.2 6.8 83.5 369.7 7.7 23.0 108.6 33.2 40.1 297.0 26.2 22.4 240.5 199.4 61.9 41.4 80.3 5.9 10.4 5.5 80.3 3.3 100.6 6.2 0.6 0.9 0.4 1.1 0.3 0.1 0.2 0.4 0.4 0.0 0.2 0.2 0.2 0.2 0.6 0.2 0.6 0.2 20.1 30.8 39.7 23.5 18.2 32.7 42.5 33.0 46.4 45.3 30.2 54.6 39.8 28.9 22.9 134.8 4.9 128.4 64.0 127.7 42.7 118.4 50.4 23.4 145.5 80.1 35.3 77.3 77.2 55.1 9.4 32.4 1.9 78.7 0.6 61.7 61.1 47.2 7.3 2.1 36.3 101.8 26.9 65.4 57.6 100.2 49.5 21.2 27.8 18.2 27.6 15.2 35.9 19.9 14.2 44.3 56.7 3.1 19.3 29.3 46.2 75.9 17.4 70.9 2.1 184.5 156.1 165.9 23.8 25.9 9.2 103.4 11.2 32.4 27.0 60.2 32.9 29.0 63.3 1.7 2.4 27.7 103.7 39.7 10.9 18.1 15.5 77.7 FAM171B "FLJ34104, KIAA1946" ENSG00000144369 "Family with sequence similarity 171 member B" Q6P995 2 186694060-186765959 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8" "Group enriched" "Detected in many" 5 "Astrocytes: 258.6;Bipolar cells: 141.4;Excitatory neurons: 126.5;Inhibitory neurons: 114.2;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 78.5" "Cancer enriched" "Detected in many" 5 "glioma: 15.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 43.7;U-138 MG: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010639, HPA013434" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" "HPA010639: AB_1852447, HPA013434: AB_2262499" "unprognostic (2.52e-1)" "unprognostic (7.75e-3)" "unprognostic (1.27e-1)" "unprognostic (1.04e-2)" "unprognostic (4.03e-2)" "unprognostic (9.43e-2)" "unprognostic (6.78e-3)" "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (9.51e-7)" "unprognostic (4.63e-3)" "unprognostic (1.52e-1)" "unprognostic (2.24e-3)" "prognostic unfavorable (5.03e-4)" 2.9 14.4 36.1 1.5 52.2 0.5 3.4 8.3 54.8 6.6 0.0 1.8 1.0 7.5 2.1 1.9 2.7 4.9 1.4 52.8 33.0 1.2 0.3 1.4 1.2 15.0 16.9 10.2 1.0 7.6 10.7 3.3 17.6 2.7 2.0 24.1 23.0 2.3 0.7 3.7 1.4 4.4 17.2 1.5 2.0 0.9 28.3 2.8 2.2 3.6 1.1 2.2 2.2 30.1 4.2 4.9 7.2 22.6 20.9 15.7 0.1 4.5 8.0 5.5 7.8 13.6 21.9 0.0 1.6 12.9 9.3 0.5 9.9 4.3 7.8 0.0 5.7 5.1 2.1 0.0 1.6 1.5 1.7 20.2 1.8 4.2 3.4 7.1 12.1 3.9 0.0 43.7 10.5 2.9 3.0 0.0 9.6 0.0 4.9 0.0 13.9 1.0 8.5 15.8 22.4 12.2 2.3 1.4 6.1 4.2 1.7 1.0 7.1 29.7 3.9 0.5 2.9 11.5 12.0 0.0 9.2 0.0 4.2 0.2 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.2 0.2 0.0 0.0 36.1 52.2 8.3 54.8 52.8 33.0 15.0 16.9 17.6 17.2 28.3 30.1 9.1 0.0 0.0 258.6 0.1 8.9 2.8 1.2 4.0 141.4 10.7 5.7 0.8 5.7 5.7 0.0 14.6 11.4 0.5 0.0 0.0 1.0 1.3 1.5 13.0 14.4 4.8 1.3 126.5 0.4 0.8 14.1 2.6 4.7 0.0 0.8 6.8 0.1 2.0 23.5 114.2 0.0 4.1 0.3 2.8 4.0 7.8 1.0 3.6 18.7 0.7 16.2 0.0 102.1 78.5 0.7 0.0 13.9 0.2 1.4 0.0 0.2 2.6 17.0 0.0 8.6 4.5 0.4 1.5 0.6 5.3 8.2 0.9 2.6 0.0 1.1 ZSWIM2 "MEX, MGC33890, ZZZ2" ENSG00000163012 "Zinc finger SWIM-type containing 2" Q8NEG5 2 186827475-186849208 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 9.3" "Cell type enhanced" "Detected in some" "Early spermatids: 61.1;Late spermatids: 18.6;Spermatocytes: 11.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.00e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 18.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 TFPI "EPI, LACI, TFI, TFPI1" ENSG00000003436 "Tissue factor pathway inhibitor" P10646 2 187464230-187565760 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 272.3;placenta: 191.2" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2284.2;Hepatic stellate cells: 872.4;Syncytiotrophoblasts: 879.2" "Cancer enhanced" "Detected in all" "liver cancer: 22.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.3;neutrophil: 1.3;plasmacytoid DC: 2.7" "Group enriched" "Detected in many" 6 "dendritic cells: 2.7;granulocytes: 3.3" "Cell line enhanced" "Detected in many" "HHSteC: 386.2;HUVEC TERT2: 742.5;LHCN-M2: 459.9;TIME: 451.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA005575, CAB020842" Supported "Secreted to blood" NA NA 58100000 87000000 "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB020842: , HPA005575: AB_1080290" "unprognostic (8.75e-2)" "prognostic unfavorable (2.02e-4)" "unprognostic (7.95e-2)" "unprognostic (4.99e-2)" "unprognostic (2.32e-2)" "unprognostic (1.48e-1)" "unprognostic (3.05e-1)" "unprognostic (5.63e-2)" "unprognostic (3.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.43e-2)" "unprognostic (2.72e-2)" "unprognostic (7.05e-2)" "unprognostic (3.39e-3)" "unprognostic (4.05e-2)" "unprognostic (4.49e-2)" "unprognostic (5.81e-2)" 67.5 12.6 2.6 20.5 3.4 8.2 52.3 4.9 5.8 41.5 7.4 23.3 52.5 25.7 18.5 33.3 35.6 57.6 38.5 4.1 2.2 56.3 272.3 126.7 33.3 6.8 2.5 26.5 25.0 7.1 6.1 191.2 3.9 15.7 27.4 4.5 15.0 12.8 26.8 19.8 41.8 30.7 3.7 20.7 19.2 6.9 3.6 11.1 36.2 42.8 17.7 52.9 29.8 3.2 38.9 24.7 29.3 0.8 224.3 267.7 0.7 66.0 156.3 42.7 65.1 22.6 192.6 0.7 27.3 52.7 74.7 2.1 15.9 3.6 110.3 1.9 7.6 12.3 73.8 197.3 386.2 0.9 0.4 123.1 5.1 232.8 61.9 93.4 742.5 0.7 31.2 0.7 459.9 35.4 4.6 0.7 22.9 0.8 68.8 0.3 40.2 0.3 72.9 1.4 0.3 0.5 56.7 2.1 3.5 95.8 0.7 0.2 451.4 30.6 29.0 61.4 13.5 1.1 1.7 0.4 239.4 0.6 35.4 3.3 0.2 0.2 0.2 0.1 0.1 0.4 0.1 0.0 0.2 0.5 0.2 0.2 1.3 0.5 0.1 2.7 0.1 2.3 2.6 3.4 4.9 5.8 4.1 2.2 6.8 2.5 3.9 3.7 3.6 3.2 99.2 35.3 335.5 1.3 4.4 20.8 2.9 33.5 4.6 0.6 16.1 9.1 7.0 173.0 102.5 38.6 0.0 59.5 4.8 0.5 13.7 140.0 41.5 7.3 74.2 287.1 105.0 43.1 0.7 273.1 2284.2 283.0 12.2 5.3 13.9 1.5 872.4 382.1 50.2 1.7 0.2 11.3 158.7 63.7 41.3 15.2 171.8 21.9 26.6 13.1 33.7 33.1 1.0 0.0 0.1 157.6 34.1 70.0 9.5 8.0 36.6 109.4 45.2 1.1 216.9 141.2 127.8 2.7 0.5 10.2 18.5 879.2 8.1 30.6 18.5 16.7 GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 136.5;Inhibitory neurons: 115.5;Muller glia cells: 129.4;Syncytiotrophoblasts: 204.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.9;SH-SY5Y: 83.4;WM-115: 228.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020587: AB_1850452" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (3.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (9.28e-2)" "unprognostic (8.25e-3)" "unprognostic (2.23e-1)" "prognostic favorable (4.25e-6)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.29e-1)" "unprognostic (7.33e-2)" "unprognostic (3.04e-4)" 9.4 24.5 2.0 5.8 6.4 0.2 13.1 0.0 4.3 27.7 33.0 13.3 13.5 35.3 83.0 19.2 18.2 17.5 5.2 3.6 7.3 21.3 0.8 13.3 1.7 22.7 4.1 31.8 22.2 26.1 3.4 19.7 23.2 27.7 7.8 17.7 16.1 28.1 9.6 6.2 15.8 21.7 0.3 5.9 22.6 28.0 4.0 1.7 7.8 16.7 3.3 11.9 14.3 0.1 12.5 26.9 106.9 23.8 17.1 15.5 18.6 16.5 27.0 25.1 19.9 18.9 62.6 0.0 13.2 13.2 28.2 8.3 20.0 1.5 18.9 0.0 13.9 27.0 20.5 0.2 15.1 0.0 0.2 10.1 4.2 13.0 14.2 42.9 12.7 0.0 22.5 0.5 19.3 1.8 0.0 0.4 27.4 18.1 46.0 0.1 25.1 14.0 60.0 4.7 0.5 83.4 0.0 14.6 40.2 47.9 4.7 0.1 5.9 7.8 3.8 26.3 9.6 0.0 0.1 0.0 4.6 0.0 228.6 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 6.4 0.0 4.3 3.6 7.3 22.7 4.1 23.2 0.3 4.0 0.1 22.8 16.0 13.4 43.4 1.6 15.7 23.9 3.6 10.2 1.5 10.6 12.2 1.6 45.8 28.2 23.9 0.0 41.1 0.6 3.7 45.0 33.0 5.0 23.9 35.4 32.1 136.5 0.0 82.7 38.2 5.9 55.3 39.8 52.1 0.0 2.2 10.0 1.5 3.2 1.7 115.5 4.6 14.2 1.0 10.5 7.9 20.5 2.0 35.6 53.4 1.1 129.4 0.0 3.0 3.1 51.3 9.8 61.3 1.4 79.8 30.8 43.2 43.5 3.7 6.6 42.2 27.9 79.6 23.9 38.9 27.6 204.4 2.7 27.0 4.7 34.5 COL3A1 EDS4A ENSG00000168542 "Collagen type III alpha 1 chain" P02461 2 188974373-189012746 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aortic aneurysm, Disease variant, Ehlers-Danlos syndrome, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 2369.0;gallbladder: 2092.8;placenta: 1981.7;smooth muscle: 2140.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2812.0;Fibroblasts: 1764.2;Smooth muscle cells: 643.0;Theca cells: 466.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebral cortex: 15.0;thalamus: 10.9;white matter: 4.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 1362.4;ASC diff: 2465.0;ASC TERT1: 4252.6;fHDF/TERT166: 1815.7;HHSteC: 1690.0;HSkMC: 3189.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 61.1" "HPA007583, CAB016766, CAB059993" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 32000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB016766: , CAB059993: AB_2314211, HPA007583: AB_1078548" "unprognostic (1.12e-1)" "unprognostic (2.03e-2)" "unprognostic (1.02e-1)" "unprognostic (6.01e-2)" "unprognostic (2.78e-1)" "unprognostic (2.04e-1)" "unprognostic (6.94e-2)" "unprognostic (6.77e-3)" "unprognostic (3.57e-3)" "unprognostic (2.60e-2)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (3.59e-10)" "unprognostic (1.70e-3)" "unprognostic (3.76e-2)" "unprognostic (7.61e-2)" "unprognostic (6.17e-3)" 763.6 48.9 1.1 575.5 2.3 1.1 340.0 1.4 15.0 2369.0 11.5 275.9 84.5 768.9 60.9 298.5 177.6 2092.8 234.6 1.3 1.4 42.9 97.4 187.0 119.0 1.8 2.0 146.9 45.2 37.0 13.6 1981.7 2.2 147.5 334.7 0.0 65.6 276.9 67.1 329.8 152.5 2140.7 1.9 134.7 156.9 63.5 10.9 40.9 71.8 71.8 73.1 1097.6 273.8 4.6 0.0 0.2 1362.4 53.0 2465.0 4252.6 0.9 558.6 495.3 239.4 212.8 8.1 0.0 0.6 0.3 1815.7 0.1 0.8 1.1 1.0 26.4 0.0 0.9 0.7 228.9 0.2 1690.0 2.0 0.6 3189.5 0.0 291.5 46.9 1.0 12.5 0.0 0.4 0.0 146.4 0.0 0.2 1.4 2.6 0.1 1.7 0.3 38.5 0.5 0.0 7.2 1.3 21.1 14.5 0.4 0.0 954.8 0.1 0.0 0.7 2.3 28.0 117.3 0.5 2.8 1.3 0.4 0.5 1.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.3 1.4 15.0 1.3 1.4 1.8 2.0 2.2 1.9 10.9 4.6 111.8 3.2 13.7 0.0 0.6 171.6 0.4 1.9 3.4 0.0 7.7 9.9 11.1 0.0 1.3 0.0 0.0 57.9 1.6 0.0 0.0 2.4 29.0 75.4 2812.0 68.4 6.0 0.0 0.0 0.0 58.1 1764.2 4.1 60.7 6.3 9.7 235.2 0.9 91.1 0.0 0.2 0.0 0.0 0.6 275.3 20.8 323.1 17.5 172.5 20.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 235.9 1.5 0.6 0.0 0.2 1.6 0.0 453.6 224.3 643.0 0.9 1.5 2.2 155.7 126.3 29.1 466.8 0.0 0.4 COL5A2 ENSG00000204262 "Collagen type V alpha 2 chain" P05997 2 189031898-189225312 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 186.0;Excitatory neurons: 185.2;Fibroblasts: 145.7;Skeletal myocytes: 76.4;Smooth muscle cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 447.8;BJ hTERT+ SV40 Large T+ RasG12V: 382.4;fHDF/TERT166: 430.3;HSkMC: 340.2;SuSa: 373.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA 820000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (7.45e-2)" "unprognostic (6.44e-3)" "unprognostic (1.22e-1)" "unprognostic (9.31e-2)" "unprognostic (2.01e-1)" "unprognostic (1.13e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (5.37e-4)" "unprognostic (5.97e-2)" "unprognostic (1.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (1.53e-10)" "unprognostic (4.57e-3)" "unprognostic (3.76e-2)" "unprognostic (8.30e-2)" "prognostic unfavorable (3.58e-4)" 61.0 4.8 2.3 42.5 5.7 0.2 25.7 0.0 15.6 83.4 3.1 48.7 10.0 43.4 32.7 23.6 21.2 81.9 19.5 17.6 0.8 6.3 12.4 26.1 9.3 2.0 17.4 25.2 7.1 7.5 7.3 111.5 3.8 14.8 25.4 1.6 7.4 12.8 7.8 12.9 22.8 98.3 1.9 10.0 21.5 6.8 1.0 4.7 9.8 26.8 10.3 57.3 29.7 2.5 0.4 93.5 143.9 67.5 212.0 285.3 0.8 213.7 242.3 447.8 382.4 63.2 0.7 0.2 2.2 430.3 23.2 1.6 4.1 2.3 153.3 0.9 1.3 1.0 2.1 0.6 282.6 0.6 0.4 340.2 7.8 129.8 45.3 92.2 108.5 0.9 0.5 0.4 109.1 2.4 0.3 0.3 20.9 0.9 124.3 0.5 33.9 0.4 0.5 24.9 2.0 1.4 5.2 2.5 5.2 373.0 2.1 0.2 91.6 212.8 22.9 52.6 44.6 0.8 0.4 0.6 32.2 0.1 235.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 5.7 0.0 15.6 17.6 0.8 2.0 17.4 3.8 1.9 1.0 2.5 36.7 0.0 1.5 29.7 0.3 26.1 0.2 7.2 6.2 1.3 1.6 3.7 2.8 0.0 0.7 1.8 0.0 4.6 0.2 0.5 1.9 0.6 0.7 22.4 186.0 9.1 38.7 0.0 185.2 0.7 3.9 145.7 0.5 5.1 0.0 4.2 25.7 7.4 6.6 0.0 23.8 0.2 4.1 0.3 27.4 1.7 48.7 1.4 21.4 25.3 0.6 0.7 0.0 21.6 10.9 1.1 0.1 19.5 0.4 0.3 0.1 1.0 1.9 0.8 46.0 76.4 116.0 3.9 1.8 2.0 18.8 6.2 2.8 27.4 0.0 0.4 WDR75 "FLJ12519, NET16, UTP17" ENSG00000115368 "WD repeat domain 75" Q8IWA0 2 189441446-189475552 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "unprognostic (1.23e-1)" "unprognostic (7.34e-2)" "unprognostic (3.31e-1)" "unprognostic (1.54e-1)" "unprognostic (4.22e-2)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.50e-8)" "unprognostic (1.49e-1)" "unprognostic (2.46e-3)" "unprognostic (1.93e-2)" "unprognostic (3.25e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.15e-11)" "unprognostic (1.34e-1)" "unprognostic (7.56e-2)" "unprognostic (1.10e-1)" "unprognostic (1.38e-2)" 18.0 21.1 16.5 18.7 16.6 20.5 24.3 17.9 20.5 23.5 14.7 16.3 13.8 23.4 23.8 18.0 21.2 14.9 13.7 16.3 17.3 15.5 17.7 12.3 26.3 17.5 16.1 23.4 19.8 17.3 13.5 16.9 17.5 15.1 18.2 15.8 13.6 13.1 15.9 21.9 16.0 19.5 17.9 21.6 16.3 16.1 17.6 20.6 14.7 13.8 24.1 23.1 17.9 19.4 36.0 34.3 43.7 55.2 46.7 49.5 49.2 73.3 34.1 82.0 62.7 71.5 39.7 76.1 41.0 24.1 31.6 48.3 81.9 49.0 79.7 49.9 39.1 99.5 60.3 55.4 44.4 111.2 48.7 41.1 41.3 59.4 80.6 34.7 55.9 43.5 99.9 45.3 56.3 35.7 54.8 77.4 101.6 41.5 92.6 51.0 65.4 64.0 41.3 42.5 41.2 41.9 46.1 44.1 38.1 70.2 40.7 45.9 48.3 48.7 52.4 37.4 55.3 48.7 81.2 95.1 34.5 47.5 40.3 0.7 4.3 2.5 5.7 7.4 11.3 5.9 6.3 7.4 8.0 4.3 7.7 7.5 0.0 7.6 4.6 4.5 8.4 4.7 16.5 16.6 17.9 20.5 16.3 17.3 17.5 16.1 17.5 17.9 17.6 19.4 19.8 28.9 16.4 20.5 20.4 17.0 21.0 16.6 26.7 6.4 8.3 9.7 18.3 2.8 13.1 1.8 8.4 19.0 13.3 4.2 11.7 15.0 2.1 10.6 27.3 18.0 9.0 15.8 32.8 16.9 16.0 17.8 15.3 12.0 5.1 13.7 9.7 8.5 10.7 16.8 41.2 12.1 20.3 44.5 8.5 3.8 18.0 11.9 14.2 12.2 11.4 4.8 9.2 28.6 29.7 16.3 6.7 15.8 14.9 16.6 6.1 14.6 11.3 9.6 19.7 20.4 19.6 30.5 31.4 18.1 11.2 17.2 19.5 17.0 11.4 15.2 SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 489.8;Kupffer cells: 1340.2;Syncytiotrophoblasts: 2463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 326.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 509.0;CACO-2: 123.1;HEL: 430.0;HMC-1: 110.5;T-47d: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: AB_2685524" "unprognostic (1.28e-2)" "unprognostic (1.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.83e-2)" "unprognostic (8.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.66e-1)" "unprognostic (6.22e-2)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "unprognostic (6.43e-2)" "unprognostic (6.44e-2)" "prognostic favorable (8.55e-5)" "unprognostic (4.66e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.11e-2)" 59.6 333.5 9.3 52.6 11.9 45.8 97.7 9.6 9.8 156.3 10.4 124.7 289.3 95.4 61.6 30.5 214.2 148.7 52.6 7.2 12.0 79.9 251.5 122.9 172.6 15.6 15.7 317.2 53.2 91.8 19.0 250.1 12.8 39.5 130.8 29.5 58.7 53.1 64.2 12.2 127.9 69.3 15.5 368.1 96.8 33.2 13.9 62.6 68.0 60.3 59.1 53.1 21.8 11.3 0.0 7.4 0.6 0.0 509.0 3.3 25.4 0.2 6.6 1.9 3.1 123.1 0.4 0.2 1.0 0.2 1.4 0.4 2.4 0.3 1.6 0.3 1.7 430.0 1.7 45.8 1.9 1.5 110.5 35.9 0.2 1.2 0.0 11.7 13.0 16.4 44.6 1.1 6.3 0.0 18.2 28.8 1.5 92.7 1.7 0.2 5.0 2.5 5.3 18.1 1.0 5.4 0.8 35.4 0.0 39.5 207.6 6.2 0.3 0.8 11.7 0.5 0.1 1.1 0.2 0.3 0.1 0.2 0.1 129.8 101.5 172.1 2.2 23.7 3.2 0.2 54.4 4.9 115.6 0.7 80.2 17.8 326.2 4.6 2.6 18.8 5.3 105.8 9.3 11.9 9.6 9.8 7.2 12.0 15.6 15.7 12.8 15.5 13.9 11.3 44.2 125.0 40.3 3.6 12.0 9.2 51.3 10.5 19.9 4.8 83.8 30.0 48.0 138.7 31.6 33.1 4.2 489.8 5.7 328.9 49.0 54.7 10.5 39.6 38.2 39.8 18.6 253.7 0.3 71.8 20.3 81.9 76.5 129.5 9.5 12.8 245.9 259.7 86.4 6.7 6.8 60.8 6.1 1340.2 26.8 9.2 121.2 172.7 8.8 34.7 41.7 17.5 2.1 14.6 0.2 71.5 86.2 58.6 4.1 26.2 163.0 150.0 34.4 48.4 65.7 13.7 49.1 7.4 3.9 12.5 8.1 2463.5 11.9 84.8 48.9 27.7 ASNSD1 "FLJ20752, NBLA00058, NS3TP1" ENSG00000138381 "Asparagine synthetase domain containing 1" Q9NWL6 2 189661385-189670831 "Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036132, HPA036133, HPA075042" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036132: AB_2674960, HPA036133: AB_10696650, HPA075042: AB_2686731" "unprognostic (1.32e-1)" "unprognostic (1.70e-1)" "unprognostic (4.88e-2)" "unprognostic (2.15e-3)" "prognostic favorable (4.54e-4)" "unprognostic (8.42e-2)" "prognostic unfavorable (8.66e-4)" "unprognostic (5.68e-2)" "unprognostic (1.35e-2)" "unprognostic (1.41e-3)" "unprognostic (2.09e-1)" "unprognostic (6.32e-3)" "unprognostic (8.98e-3)" "unprognostic (8.11e-2)" "unprognostic (2.52e-1)" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" 27.1 26.1 23.1 19.2 24.5 36.9 33.5 31.8 33.5 27.9 21.3 21.1 22.5 28.6 19.6 21.3 24.0 19.7 32.2 23.6 25.5 30.5 40.4 21.9 27.1 24.2 24.0 37.6 27.1 33.2 19.1 33.7 24.5 21.6 18.3 40.2 25.2 20.8 59.6 17.5 17.7 28.1 24.6 23.0 20.4 17.5 24.1 27.9 26.3 70.5 25.1 27.4 17.1 25.9 33.1 22.0 53.5 42.5 58.9 50.4 47.2 66.4 57.1 65.7 67.5 72.5 22.6 65.3 39.0 61.9 36.4 26.5 60.2 49.2 76.6 65.4 72.5 57.5 48.5 69.2 61.4 59.9 33.2 59.9 37.2 66.3 58.9 46.5 63.3 46.9 58.6 49.6 69.6 43.2 68.8 68.9 81.0 55.3 102.4 41.3 43.4 62.4 39.0 40.2 59.5 31.2 41.7 35.0 59.1 66.7 52.3 55.9 57.0 56.6 44.5 48.1 73.4 73.7 86.5 93.4 44.1 33.9 52.7 82.8 26.1 107.6 38.8 22.7 48.6 37.2 42.3 43.3 26.7 37.2 49.4 45.3 48.9 49.1 25.2 21.4 57.6 37.3 23.1 24.5 31.8 33.5 23.6 25.5 24.2 24.0 24.5 24.6 24.1 25.9 31.3 54.5 34.9 10.1 41.1 30.0 24.4 31.2 25.0 22.4 29.7 25.9 43.7 28.6 35.6 16.5 12.5 67.2 36.1 24.1 82.2 35.7 7.0 24.8 34.9 31.1 36.0 41.7 17.2 45.3 43.3 41.8 16.8 22.8 19.0 24.6 29.6 51.9 34.1 15.2 18.9 25.2 26.4 28.0 23.7 5.6 40.7 24.5 17.8 7.5 34.7 40.5 50.4 14.6 17.6 36.5 12.0 33.8 37.9 23.0 18.7 56.7 29.4 27.0 46.0 48.7 47.9 30.3 43.8 29.4 28.4 119.9 42.7 30.9 27.7 19.3 ASDURF ENSG00000286053 "ASNSD1 upstream reading frame" L0R819 2 189661452-189666437 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 33.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 16: U-266 - Nucleosome" 1.3 0.7 1.5 3.4 0.9 3.4 1.9 1.1 1.8 0.0 0.9 2.9 2.1 2.1 2.3 2.4 2.5 4.9 1.0 1.0 1.0 2.1 3.3 0.9 6.2 1.3 0.7 4.3 3.1 0.6 2.6 1.5 2.2 3.2 3.8 1.3 2.3 3.5 1.4 1.9 3.2 0.9 2.8 0.3 1.9 1.0 0.4 4.4 0.0 3.8 2.2 1.3 3.8 4.6 2.6 4.3 0.8 9.8 2.9 12.3 14.0 13.8 11.1 0.0 1.7 8.5 8.1 3.1 2.7 2.8 0.7 4.8 15.4 14.3 5.6 12.1 2.3 2.4 4.4 10.0 2.7 0.9 0.8 5.3 2.4 3.8 8.3 0.7 7.0 1.1 4.8 5.9 10.2 1.1 2.9 0.0 24.0 3.1 11.2 4.8 5.1 9.6 4.5 8.4 17.2 4.7 6.2 3.3 5.0 3.1 1.8 7.4 5.7 9.1 3.4 2.3 26.5 33.8 10.0 5.9 5.2 0.0 0.5 0.1 0.8 0.8 0.1 0.1 0.8 0.1 0.4 0.2 1.6 1.3 0.8 3.2 2.4 1.6 1.8 0.1 1.5 0.9 1.1 1.8 1.0 1.0 1.3 0.7 1.5 0.9 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC012488.2 ENSG00000286165 "Novel protein" 2 189661519-189667881 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 2.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.7" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 1.2;HDLM-2: 1.2" HPA075042 Approved Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" Cytosol "HPA075042: AB_2686731" 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.2 2.7 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.2 0.8 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.3 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.4 0.7 1.1 0.4 0.4 0.3 1.3 0.4 0.0 0.2 2.1 0.3 0.2 0.5 0.6 0.2 1.0 2.3 0.4 0.2 0.3 0.2 2.7 0.2 0.2 0.3 0.1 0.4 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANKAR FLJ25415 ENSG00000151687 "Ankyrin and armadillo repeat containing" Q7Z5J8 2 189674290-189761193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 5.8" "Cell type enhanced" "Detected in many" "Astrocytes: 82.9;Early spermatids: 88.8;Inhibitory neurons: 60.6;Oligodendrocyte precursor cells: 87.0;Oligodendrocytes: 80.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036168 Uncertain Approved "Nucleoplasm,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Centriolar satellite" Nucleoplasm "HPA036168: AB_10673345" "unprognostic (2.12e-2)" "unprognostic (1.23e-1)" "unprognostic (1.06e-2)" "unprognostic (5.41e-2)" "unprognostic (3.14e-1)" "unprognostic (1.95e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-1)" "unprognostic (2.65e-2)" "unprognostic (5.03e-3)" "unprognostic (2.89e-1)" "unprognostic (2.65e-2)" "unprognostic (6.34e-4)" "unprognostic (2.43e-1)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.47e-2)" 0.2 0.4 0.2 0.2 0.3 0.2 0.4 1.0 0.3 0.2 1.4 0.2 0.2 0.4 0.6 0.2 0.3 0.3 0.1 0.2 0.3 0.2 0.4 0.3 0.5 0.3 0.3 0.3 0.5 0.6 0.1 0.3 0.3 0.5 0.4 0.6 0.5 0.2 0.1 0.3 0.3 0.2 0.2 0.4 0.5 5.8 0.3 0.1 0.5 0.0 0.3 0.2 0.1 0.6 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.3 0.0 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.4 0.6 0.1 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.0 0.3 0.2 0.3 0.3 0.3 0.3 0.2 0.3 0.6 10.5 3.2 8.2 82.9 13.4 1.3 7.2 2.5 5.2 12.6 4.1 3.8 4.7 4.3 2.8 11.0 14.6 1.2 8.1 3.3 1.9 3.3 88.8 2.8 8.4 8.9 0.0 10.1 46.0 4.3 1.1 9.7 13.3 2.8 0.0 8.4 7.1 2.4 2.4 3.3 60.6 5.7 2.0 1.9 4.9 46.1 21.8 5.6 7.2 47.8 3.4 6.1 13.4 87.0 80.5 4.5 5.6 13.9 5.1 4.1 4.8 2.7 1.5 46.2 6.6 15.8 8.4 20.3 11.1 5.2 1.3 0.1 9.6 4.8 4.2 4.1 OSGEPL1 "OSGEPL, Qri7" ENSG00000128694 "O-sialoglycoprotein endopeptidase like 1" Q9H4B0 2 189746660-189763227 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030693 Uncertain Supported Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA030693: AB_10601978" "unprognostic (1.10e-1)" "unprognostic (8.72e-2)" "unprognostic (8.19e-2)" "unprognostic (6.70e-2)" "unprognostic (6.07e-2)" "unprognostic (6.38e-2)" "prognostic unfavorable (3.71e-4)" "unprognostic (4.18e-3)" "unprognostic (1.06e-3)" "prognostic favorable (3.19e-4)" "unprognostic (2.33e-1)" "unprognostic (1.80e-2)" "unprognostic (3.34e-2)" "unprognostic (2.68e-1)" "unprognostic (1.51e-2)" "unprognostic (6.39e-2)" "unprognostic (1.55e-3)" 3.9 8.2 3.6 3.5 5.0 1.9 7.2 6.1 5.0 4.5 3.0 3.5 3.3 5.7 5.6 4.0 5.2 3.2 8.9 3.4 4.0 8.4 7.9 3.9 6.5 4.3 4.5 8.7 3.1 4.7 2.7 4.0 4.5 4.1 3.9 9.8 4.7 3.7 12.3 6.1 3.5 5.0 4.3 5.4 3.1 6.4 3.9 5.6 5.2 11.0 6.3 3.6 3.0 6.1 7.1 3.8 16.7 12.7 12.9 7.1 9.8 10.8 7.5 14.9 15.9 4.5 7.1 4.7 11.7 4.5 8.2 10.1 15.0 12.7 16.9 12.3 11.5 15.3 9.0 5.9 6.7 8.8 7.6 7.8 10.6 11.5 5.5 10.2 11.3 11.8 5.6 7.2 9.8 3.9 6.8 9.9 8.1 9.5 17.4 7.5 13.4 8.1 9.7 3.8 10.1 11.2 7.3 12.8 23.9 20.6 10.1 9.9 4.7 9.6 8.5 14.3 6.8 7.3 6.6 7.4 12.7 11.0 10.7 0.5 2.7 2.3 7.5 2.7 10.6 7.7 7.7 8.6 3.8 9.8 11.3 10.5 0.4 7.6 2.4 6.6 6.6 3.1 3.6 5.0 6.1 5.0 3.4 4.0 4.3 4.5 4.5 4.3 3.9 6.1 3.6 6.4 3.6 6.8 8.4 1.9 2.8 5.9 5.2 8.9 4.0 4.8 8.6 8.6 2.8 0.0 12.5 10.6 7.3 0.4 7.9 3.0 1.4 3.5 5.5 4.1 0.0 5.2 6.6 2.3 7.3 4.5 1.5 2.3 3.8 6.8 3.6 2.9 4.4 10.1 10.0 1.1 2.0 2.4 1.7 0.8 11.1 4.1 1.8 5.6 1.8 12.0 13.4 10.1 17.0 2.0 1.0 8.2 1.9 1.1 1.7 10.2 6.0 11.8 26.3 5.8 8.4 9.6 13.7 4.4 2.0 2.2 6.0 11.8 2.2 1.0 ORMDL1 ENSG00000128699 "ORMDL sphingolipid biosynthesis regulator 1" Q9P0S3 2 189770267-189784364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA065643 Supported "Endoplasmic reticulum" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 51: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum" "HPA065643: AB_2685525" "unprognostic (1.45e-1)" "unprognostic (5.34e-3)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-3)" "unprognostic (1.86e-2)" "unprognostic (6.70e-3)" "prognostic favorable (3.04e-5)" "unprognostic (5.90e-3)" "unprognostic (2.16e-2)" "prognostic unfavorable (5.84e-9)" "unprognostic (2.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.87e-2)" "prognostic favorable (1.49e-5)" 60.0 66.2 27.0 50.3 28.6 51.7 54.9 34.2 33.2 67.9 36.2 60.7 41.1 56.5 99.5 46.1 55.3 47.4 37.8 28.4 33.1 55.2 68.7 66.9 75.2 27.3 27.7 50.8 84.5 42.3 79.3 63.1 28.2 62.2 50.1 82.0 66.1 47.3 41.5 84.3 84.9 43.9 30.4 131.2 64.0 58.8 28.8 44.2 62.9 23.9 69.4 50.3 51.7 32.8 31.4 20.5 68.0 54.8 88.2 100.4 70.3 64.9 61.7 71.0 71.5 41.9 51.7 57.8 44.7 49.9 36.7 52.1 43.4 42.0 77.5 65.6 55.2 82.3 106.2 61.9 102.6 65.8 63.8 113.1 51.6 61.8 70.6 99.0 58.4 57.9 48.3 85.9 72.9 28.6 58.6 127.0 60.7 32.4 86.4 46.4 50.2 78.7 87.4 49.3 43.6 51.4 33.8 32.0 74.3 78.3 38.7 73.3 61.6 70.1 48.1 44.9 65.7 82.9 66.6 55.4 76.4 68.7 38.6 49.4 32.7 39.8 35.8 39.5 33.7 37.9 39.3 36.5 26.7 35.4 45.0 40.9 13.3 29.4 48.3 46.1 46.1 33.5 27.0 28.6 34.2 33.2 28.4 33.1 27.3 27.7 28.2 30.4 28.8 32.8 80.4 80.1 50.2 41.4 90.9 56.3 55.1 95.6 26.7 138.3 69.8 76.7 34.4 41.5 65.5 36.8 175.2 212.4 141.2 36.0 33.2 58.7 42.8 58.0 63.9 61.8 42.4 38.7 53.6 67.3 73.0 58.1 24.5 47.3 45.6 84.3 47.5 37.4 86.9 65.6 60.1 37.2 101.7 126.8 60.9 18.9 74.3 83.3 39.2 33.7 96.4 107.7 117.4 57.8 49.4 66.5 48.3 48.5 83.5 79.1 62.8 45.9 66.3 217.2 52.6 55.4 63.8 186.8 145.0 32.5 60.7 218.1 104.5 117.4 46.3 51.5 PMS1 "MLH2, PMSL1" ENSG00000064933 "PMS1 homolog 1, mismatch repair system component" P54277 2 189784085-189877629 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.4" "Group enriched" "Detected in many" 6 "Early spermatids: 474.4;Late spermatids: 570.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031013 Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" "HPA031013: AB_2673696" "unprognostic (1.03e-1)" "unprognostic (1.58e-2)" "unprognostic (9.31e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-3)" "unprognostic (1.49e-2)" "prognostic unfavorable (2.38e-6)" "unprognostic (5.31e-2)" "unprognostic (1.60e-2)" "unprognostic (7.29e-3)" "unprognostic (3.55e-1)" "unprognostic (2.30e-1)" "prognostic unfavorable (1.86e-6)" "unprognostic (1.29e-1)" "unprognostic (3.77e-2)" "unprognostic (1.92e-2)" "prognostic favorable (3.73e-4)" 9.2 9.0 9.6 12.0 8.2 12.1 11.6 14.7 9.7 10.8 7.6 7.7 7.4 13.3 15.7 6.3 9.7 8.3 7.0 7.8 10.0 6.3 7.7 8.0 13.7 7.5 8.2 11.9 8.3 7.3 9.8 8.7 8.7 9.5 9.1 18.4 9.9 10.2 9.4 11.5 8.4 10.2 7.2 13.2 13.0 48.4 9.5 8.0 10.6 6.6 10.7 7.4 7.5 11.4 13.8 11.8 29.9 23.8 16.1 24.3 26.6 25.3 12.3 21.2 25.4 19.6 18.1 39.7 14.0 10.6 15.1 19.2 29.9 18.7 29.5 30.3 17.4 39.5 24.1 30.3 22.5 23.3 17.3 15.6 18.4 19.3 39.7 18.8 22.4 27.6 34.0 20.8 26.1 9.7 27.6 32.2 31.6 14.1 27.6 31.9 19.5 38.8 20.9 19.6 27.8 19.3 18.5 12.5 19.6 36.2 13.4 20.1 17.3 22.8 15.4 14.7 23.2 16.6 21.9 34.4 13.1 20.4 14.7 2.9 6.4 3.7 13.6 4.2 13.3 14.4 10.1 15.5 6.4 15.9 10.6 13.0 3.0 12.0 5.2 10.0 10.8 4.8 9.6 8.2 14.7 9.7 7.8 10.0 7.5 8.2 8.7 7.2 9.5 11.4 18.5 16.0 14.4 45.1 22.7 6.9 8.9 12.9 21.6 30.8 13.7 14.6 16.3 10.0 15.8 5.5 8.4 16.4 18.7 3.6 0.0 7.6 474.4 17.3 26.6 14.8 12.0 10.9 68.6 8.0 11.7 18.5 13.7 11.7 13.3 27.7 8.2 9.6 9.2 10.1 80.2 7.3 16.2 16.0 5.1 570.1 21.8 14.9 7.2 43.1 9.8 11.2 22.6 80.9 64.8 6.4 4.3 19.5 30.1 7.5 4.9 6.1 27.0 28.0 13.1 16.3 15.0 25.3 25.9 19.3 7.0 5.2 20.9 22.2 11.1 4.3 C2orf88 "MGC13057, smAKAP" ENSG00000187699 "Chromosome 2 open reading frame 88" Q9BSF0 2 189879609-190203484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 73.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 496.6;Early spermatids: 1138.7;Late spermatids: 1344.3;Proximal enterocytes: 462.3" "Group enriched" "Detected in many" 4 "endometrial cancer: 16.2;glioma: 4.8;ovarian cancer: 14.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 2.7;naive B-cell: 2.8;neutrophil: 7.1;plasmacytoid DC: 3.0" "Group enriched" "Detected in many" 8 "B-cells: 2.8;dendritic cells: 3.0;granulocytes: 7.1" "Group enriched" "Detected in many" 6 "HEL: 108.4;K-562: 92.2;RT4: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049549 Approved NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" "HPA049549: AB_2680812" "unprognostic (1.20e-4)" "unprognostic (9.17e-2)" "unprognostic (4.50e-2)" "prognostic favorable (4.97e-4)" "unprognostic (6.09e-3)" "unprognostic (4.55e-2)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "prognostic unfavorable (9.39e-4)" "unprognostic (5.29e-3)" "unprognostic (2.66e-1)" "unprognostic (1.18e-1)" "prognostic favorable (7.79e-4)" "unprognostic (2.64e-2)" "unprognostic (2.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-3)" 4.2 6.6 7.6 4.4 10.9 9.8 9.2 9.5 10.0 48.3 1.9 36.0 34.7 15.8 2.2 2.6 21.0 2.7 11.8 7.7 10.7 6.4 4.7 3.5 3.3 9.3 10.7 1.9 12.7 35.1 2.7 1.7 10.3 7.2 38.6 4.5 14.1 9.4 13.4 5.6 44.5 3.9 11.0 4.8 5.1 73.2 9.1 0.5 3.6 28.8 5.3 4.8 11.8 18.6 0.1 0.3 0.9 0.3 3.6 11.7 0.8 0.4 0.5 0.2 1.1 3.5 0.2 0.7 14.2 1.1 5.9 0.3 3.0 0.0 1.4 0.6 1.9 108.4 0.4 6.9 0.3 0.7 0.0 5.4 0.3 5.8 0.3 0.2 0.3 0.4 92.2 7.1 1.6 0.4 0.3 0.8 0.4 0.3 0.1 0.4 4.2 0.5 2.2 58.8 0.9 2.2 0.2 0.2 11.6 2.0 0.0 1.1 0.8 0.7 0.7 0.3 0.3 0.5 2.0 2.1 1.0 0.5 0.1 0.0 0.5 0.9 0.0 0.0 0.0 2.7 0.0 0.1 0.1 2.8 0.0 0.0 7.1 0.1 0.0 3.0 0.0 16.5 7.6 10.9 9.5 10.0 7.7 10.7 9.3 10.7 10.3 11.0 9.1 18.6 4.1 3.2 0.5 15.3 6.4 1.5 12.9 0.6 2.2 9.1 25.0 36.4 41.5 1.5 0.0 3.7 25.0 0.1 1.1 496.6 19.6 0.5 1138.7 164.4 23.8 21.0 4.2 51.8 28.1 15.3 0.5 7.8 2.6 228.4 0.0 21.7 83.9 3.8 0.2 8.4 26.9 67.9 0.0 5.9 1.8 1344.3 9.9 57.9 26.6 12.2 4.2 2.7 7.2 22.1 44.9 3.9 227.4 6.0 27.8 3.2 462.3 33.2 0.0 12.4 0.0 9.2 3.9 37.9 6.0 2.5 2.3 0.4 3.8 6.1 35.0 3.3 MSTN GDF8 ENSG00000138379 Myostatin O14793 2 190055700-190062729 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Cytokine, Growth factor, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 10.1;tongue: 15.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.7;Cone photoreceptor cells: 4.2;Early spermatids: 17.8;Late spermatids: 4.2;Muller glia cells: 19.1" "Cancer enriched" "Detected in some" 9 "glioma: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "LHCN-M2: 25.9;RH-30: 52.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB009963 Approved "Secreted in other tissues" NA NA 7600000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "CAB009963: AB_2148798" "unprognostic (8.45e-2)" "unprognostic (2.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "prognostic favorable (2.86e-4)" "unprognostic (7.59e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-2)" "unprognostic (1.91e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-3)" "unprognostic (1.12e-4)" "unprognostic (1.06e-1)" "unprognostic (3.94e-1)" "unprognostic (6.53e-2)" "unprognostic (5.67e-4)" 0.4 0.9 0.6 0.0 0.6 0.0 0.3 0.7 0.9 1.2 0.1 0.6 0.2 0.8 0.5 1.1 0.3 0.1 0.3 0.7 0.5 0.5 0.1 0.2 0.0 0.6 0.6 0.4 0.2 0.0 0.6 0.0 0.6 0.4 0.4 3.1 0.4 0.1 10.1 0.5 0.2 0.3 0.4 0.2 0.2 0.3 0.5 0.0 0.4 15.3 0.0 0.2 0.5 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.7 0.9 0.7 0.5 0.6 0.6 0.6 0.4 0.5 0.5 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.7 0.1 0.1 0.1 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 17.8 0.1 0.1 0.1 0.0 0.0 1.4 0.2 0.0 1.4 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 19.1 0.0 0.5 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.7 0.7 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HIBCH ENSG00000198130 "3-hydroxyisobutyryl-CoA hydrolase" Q6NVY1 2 190189735-190344193 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Branched-chain amino acid catabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 230.2;Proximal tubular cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036540, HPA036541, HPA067080" Enhanced Enhanced Mitochondria NA NA 74000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036540: AB_10673355, HPA036541: AB_2675182, HPA067080: " "unprognostic (3.60e-3)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.36e-3)" "unprognostic (3.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.96e-1)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "prognostic favorable (1.22e-4)" "unprognostic (7.32e-2)" "unprognostic (1.37e-2)" "prognostic favorable (1.04e-10)" "unprognostic (1.34e-1)" "unprognostic (3.73e-1)" "unprognostic (1.36e-1)" "unprognostic (4.18e-3)" 34.0 60.1 40.6 17.4 49.2 14.5 28.5 40.5 60.3 33.4 51.0 37.5 55.9 28.1 29.1 34.9 22.5 22.3 28.7 40.7 47.7 142.2 129.0 13.9 20.5 43.9 43.1 18.6 27.2 58.2 19.1 18.6 44.9 25.5 40.9 38.4 20.9 23.2 49.2 58.7 33.9 18.3 45.0 17.8 25.6 21.7 43.3 16.8 31.7 38.5 21.9 23.7 26.6 72.6 23.5 16.1 37.0 23.8 29.9 27.6 16.9 23.1 11.4 20.8 22.1 46.8 20.2 33.3 36.1 18.1 17.0 44.4 33.2 30.7 29.5 47.0 25.1 44.5 37.7 41.4 10.7 31.8 16.7 19.8 17.8 24.3 4.8 32.3 31.6 30.4 55.2 30.3 20.8 18.2 34.3 33.6 11.1 30.2 30.2 42.4 24.8 83.8 43.8 68.4 27.9 24.0 18.0 27.2 66.8 47.2 32.0 21.3 26.5 22.8 20.8 16.1 15.8 18.7 45.2 30.9 20.7 27.4 18.6 27.8 11.9 26.4 19.5 14.2 21.3 43.5 21.8 21.0 20.9 34.7 22.9 29.6 6.0 32.0 11.3 26.7 37.0 12.7 40.6 49.2 40.5 60.3 40.7 47.7 43.9 43.1 44.9 45.0 43.3 72.6 23.3 22.4 25.8 129.3 29.8 56.0 131.4 74.9 34.1 35.3 39.1 24.1 28.6 42.9 51.3 36.8 102.2 53.6 18.8 53.5 115.4 27.4 230.2 48.0 21.4 33.3 37.8 13.0 46.4 29.4 22.3 27.7 29.6 39.3 10.2 41.1 89.3 117.4 35.3 25.2 51.5 31.4 71.2 15.7 11.7 62.9 34.8 15.9 46.2 52.5 14.1 35.5 39.1 104.0 141.1 15.6 26.6 45.5 23.3 27.9 32.4 376.2 47.6 50.5 39.5 29.9 26.2 18.0 29.4 45.5 40.6 20.0 30.7 61.7 62.7 67.8 INPP1 ENSG00000151689 "Inositol polyphosphate-1-phosphatase" P49441 2 190343570-190371665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 727.4;Late spermatids: 836.0;Urothelial cells: 229.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 96.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 96.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036698, HPA036699" Supported Approved "Centriolar satellite,Cytosol" NA NA 31000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Centriolar satellite" Cytosol "HPA036698: AB_10672226, HPA036699: AB_2675260" "unprognostic (1.08e-3)" "unprognostic (4.50e-3)" "unprognostic (3.87e-2)" "unprognostic (2.70e-1)" "unprognostic (7.85e-2)" "unprognostic (3.67e-3)" "unprognostic (4.44e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-1)" "unprognostic (2.96e-2)" "unprognostic (7.28e-2)" "unprognostic (2.41e-1)" "unprognostic (2.54e-1)" "unprognostic (3.74e-1)" "unprognostic (1.55e-1)" "prognostic favorable (1.12e-5)" "prognostic favorable (5.70e-4)" 24.0 35.0 35.6 11.4 41.2 14.8 20.7 36.5 47.5 27.4 24.5 22.3 36.7 18.1 12.5 71.9 18.9 23.5 30.9 36.2 42.0 19.6 33.1 27.9 9.3 37.5 37.0 11.8 26.6 41.6 29.6 13.4 37.6 18.2 21.0 17.0 17.0 13.4 21.2 37.4 25.3 19.6 34.7 25.8 18.2 52.9 38.1 23.7 19.0 35.7 20.9 42.1 35.8 54.0 26.7 7.4 13.9 0.0 15.0 31.8 0.3 30.9 41.5 28.8 37.5 28.8 16.5 0.2 36.3 30.5 9.3 35.8 5.4 19.9 35.0 32.8 11.7 19.5 22.1 17.5 31.5 15.2 6.0 21.6 30.6 32.9 18.6 20.7 54.7 0.3 48.6 16.3 51.3 0.1 1.1 14.3 4.2 42.3 40.4 0.7 11.2 0.3 22.6 62.2 20.6 7.8 21.7 1.4 31.7 14.4 0.1 21.0 51.0 18.4 13.2 33.3 18.5 3.1 3.5 0.3 5.7 6.0 14.9 26.2 8.3 96.0 6.9 8.1 6.3 3.3 4.3 4.7 8.7 4.4 2.4 3.6 3.9 16.2 4.7 0.2 20.3 5.1 35.6 41.2 36.5 47.5 36.2 42.0 37.5 37.0 37.6 34.7 38.1 54.0 63.0 3.2 5.5 44.1 8.0 86.4 155.4 33.2 50.7 15.0 9.9 14.6 20.9 38.6 27.5 11.0 6.2 6.9 9.7 50.4 7.9 33.4 727.4 18.8 16.0 59.6 31.1 1.7 30.3 85.4 2.6 30.7 29.6 26.9 8.8 3.8 88.5 21.9 8.8 16.8 36.7 23.7 20.3 10.7 27.3 836.0 26.8 14.0 26.6 17.8 12.2 73.2 14.4 29.7 125.6 53.1 40.8 23.7 12.9 90.7 50.6 20.8 13.0 11.9 26.3 26.0 19.4 18.1 11.4 170.2 97.3 4.0 10.4 37.8 35.4 229.0 MFSD6 FLJ20160 ENSG00000151690 "Major facilitator superfamily domain containing 6" Q6ZSS7 2 190408355-190509205 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 110.6;Respiratory ciliated cells: 88.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 79.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022274 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA022274: AB_2142776" "unprognostic (9.47e-2)" "unprognostic (7.01e-3)" "unprognostic (1.42e-1)" "unprognostic (3.15e-2)" "unprognostic (2.49e-1)" "unprognostic (4.13e-3)" "unprognostic (1.78e-2)" "unprognostic (3.08e-2)" "unprognostic (3.92e-1)" "unprognostic (3.77e-1)" "unprognostic (9.54e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.05e-4)" "unprognostic (3.46e-2)" "unprognostic (3.27e-1)" "unprognostic (9.14e-2)" "unprognostic (9.18e-2)" 20.8 40.3 29.1 12.7 31.7 7.6 21.3 37.0 40.3 21.8 0.0 31.8 19.8 10.5 32.8 40.6 19.5 15.8 17.9 35.5 27.6 10.8 2.3 26.4 14.8 45.8 48.3 4.1 16.8 64.5 35.4 8.6 52.4 23.0 28.9 14.9 30.8 32.3 6.4 29.8 24.6 14.4 28.6 20.9 32.1 7.9 38.3 19.9 38.9 14.2 20.6 22.9 21.5 51.2 25.1 15.2 0.5 5.2 10.6 13.6 20.4 12.7 25.3 8.4 10.5 5.6 31.1 39.1 5.8 26.4 15.6 41.5 7.4 22.1 9.5 79.7 11.6 20.9 14.2 2.9 4.2 8.3 6.4 2.1 39.3 12.5 8.1 27.1 3.0 30.5 5.4 42.2 2.2 9.7 38.8 1.8 3.4 27.1 16.1 8.6 1.2 34.1 15.9 45.1 47.5 12.2 17.9 41.7 24.9 1.7 13.6 9.5 12.6 1.4 2.9 16.6 19.7 19.3 8.6 13.8 13.5 16.9 6.9 4.6 1.1 0.4 1.4 0.3 1.5 1.6 1.8 2.0 1.5 0.7 0.9 1.9 0.1 2.1 0.5 0.7 3.5 0.8 29.1 31.7 37.0 40.3 35.5 27.6 45.8 48.3 52.4 28.6 38.3 51.2 48.6 32.1 20.0 7.2 7.6 6.4 11.5 11.7 10.8 9.7 16.8 9.8 21.4 5.7 30.3 23.9 8.4 0.2 14.9 25.1 0.0 13.2 46.8 27.9 5.9 26.7 35.4 7.8 55.7 20.5 0.2 8.9 31.1 22.5 24.0 8.7 16.1 0.8 4.0 28.6 47.9 42.7 12.2 4.0 8.0 13.7 5.6 12.3 8.8 11.2 9.7 6.8 3.1 41.7 110.6 24.9 20.8 5.3 14.9 13.5 13.6 1.0 88.5 7.9 0.0 16.7 7.2 1.0 1.4 28.8 18.3 0.0 17.0 18.6 21.1 22.7 NEMP2 TMEM194B ENSG00000189362 "Nuclear envelope integral membrane protein 2" A6NFY4 2 190504338-190534722 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 10.8;NK-cells: 14.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA057719 Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA057719: AB_2683510" "unprognostic (3.51e-1)" "unprognostic (9.99e-2)" "unprognostic (1.11e-3)" "unprognostic (1.05e-2)" "unprognostic (2.06e-2)" "unprognostic (1.03e-1)" "unprognostic (8.65e-3)" "unprognostic (5.70e-2)" "unprognostic (1.06e-1)" "unprognostic (5.61e-3)" "unprognostic (2.19e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.42e-4)" "unprognostic (5.82e-2)" "unprognostic (7.76e-3)" "unprognostic (4.75e-3)" "unprognostic (1.32e-1)" 1.5 1.7 0.7 2.5 1.0 1.9 1.5 2.7 1.0 1.4 0.1 1.3 0.9 1.3 1.0 1.5 1.1 1.1 1.0 0.6 0.4 1.3 1.8 1.7 3.7 0.7 0.7 0.9 1.2 1.0 1.3 1.0 0.9 1.3 0.9 1.2 2.1 0.6 0.5 2.1 1.6 1.2 0.4 2.3 1.9 3.0 0.8 4.7 1.9 0.7 3.0 1.3 1.6 1.4 5.0 2.7 1.8 2.3 1.0 2.7 4.7 3.5 3.0 3.4 4.3 4.0 6.8 7.3 2.3 1.8 2.4 8.7 2.8 7.6 6.9 5.4 2.4 5.2 2.6 2.8 2.6 5.7 1.7 2.8 3.1 15.9 4.1 3.2 1.6 8.0 4.6 8.3 6.8 2.3 6.3 2.7 1.9 2.7 2.9 2.6 3.9 3.4 3.1 3.7 3.2 2.7 5.6 0.6 5.6 3.0 1.4 6.1 2.9 7.7 6.0 1.5 3.9 4.5 5.4 3.8 6.0 5.8 5.7 0.0 0.4 0.0 1.5 0.4 2.0 1.3 1.7 1.3 0.5 1.9 2.7 2.3 0.1 1.3 0.3 1.9 3.1 1.2 0.7 1.0 2.7 1.0 0.6 0.4 0.7 0.7 0.9 0.4 0.8 1.4 4.5 0.0 0.6 0.0 5.9 0.0 2.1 0.0 4.0 5.5 2.0 1.3 1.6 0.0 0.0 1.8 0.0 3.0 10.8 0.2 0.0 2.0 4.5 0.9 3.3 4.0 0.0 4.6 0.0 2.0 3.1 4.1 2.0 1.2 1.3 5.4 3.9 3.4 2.9 3.3 0.0 1.0 0.0 3.3 0.0 6.2 2.8 3.1 0.0 0.0 2.4 2.5 14.4 0.0 0.0 0.7 1.8 1.2 9.5 2.1 0.6 2.3 0.0 2.0 0.0 4.9 5.1 17.0 6.1 3.9 0.0 1.2 6.4 5.3 1.7 2.2 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 GLS "GLS1, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 316.8" "Cell type enhanced" "Detected in all" "Collecting duct cells: 391.8;Excitatory neurons: 427.1;Proximal tubular cells: 539.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 907.3;RPTEC TERT1: 419.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036223 Enhanced Supported Mitochondria "Intracellular and membrane" No No 92000 "Cluster 44: Non-specific - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA036223: AB_10669984" "unprognostic (7.45e-2)" "unprognostic (3.42e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (3.45e-4)" "unprognostic (1.17e-1)" "unprognostic (2.08e-3)" "unprognostic (2.51e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (8.01e-2)" "unprognostic (9.06e-2)" "unprognostic (5.41e-2)" "unprognostic (1.62e-1)" "unprognostic (5.03e-2)" "unprognostic (2.13e-1)" "unprognostic (4.12e-1)" 37.0 77.4 38.5 45.7 50.5 28.7 32.0 40.5 74.6 31.0 35.6 32.0 92.2 28.8 26.6 16.8 25.1 41.8 34.7 55.5 35.9 316.8 11.7 55.6 68.0 44.7 19.8 28.9 36.9 62.0 19.9 35.8 52.5 20.8 30.1 81.8 20.4 31.2 15.8 28.5 103.4 36.9 12.0 49.3 18.7 16.2 24.1 41.7 35.7 23.6 57.9 36.5 23.6 44.8 43.6 47.2 32.4 43.1 99.7 68.9 84.0 126.8 95.7 90.6 103.1 58.1 42.1 88.5 907.3 269.3 46.1 55.6 58.0 50.0 131.5 219.8 37.7 147.3 69.1 72.2 90.8 87.2 66.5 62.9 51.0 71.2 48.4 90.1 119.3 36.7 69.3 175.2 203.3 22.8 59.2 83.7 86.9 25.7 76.7 74.2 83.7 77.4 419.2 78.9 44.9 46.8 172.8 37.9 169.2 115.1 14.9 53.0 85.3 129.4 94.5 65.9 156.8 56.2 138.9 122.1 46.7 70.6 105.5 6.4 1.0 1.9 3.7 1.5 6.5 3.4 4.4 4.8 1.6 3.8 4.5 5.5 2.1 2.8 1.1 3.6 4.1 1.1 38.5 50.5 40.5 74.6 55.5 35.9 44.7 19.8 52.5 12.0 24.1 44.8 81.0 189.1 122.5 61.0 89.3 174.5 44.7 15.6 60.9 93.5 51.8 49.5 38.2 35.8 28.4 391.8 210.6 4.4 128.0 100.6 50.9 21.4 6.6 33.7 66.8 68.3 59.2 17.9 427.1 24.5 15.6 66.0 46.4 97.9 36.8 48.2 63.5 4.3 29.1 26.9 270.5 36.7 14.2 31.2 230.0 7.3 28.6 84.3 88.9 143.4 68.4 11.9 55.6 163.3 146.9 29.8 92.9 43.2 118.4 70.1 165.9 539.1 17.0 111.9 19.7 71.6 76.0 11.3 12.9 61.7 162.8 4.0 114.0 97.8 43.6 56.7 STAT1 "ISGF-3, STAT91" ENSG00000115415 "Signal transducer and activator of transcription 1" P42224 2 190908460-191020960 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+ SV40 Large T+: 533.6;BJ hTERT+ SV40 Large T+ RasG12V: 595.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000931, HPA000982, CAB004049" Approved Enhanced Nucleoplasm,Cytosol NA NA 92000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" Nucleoplasm Cytosol "CAB004049: AB_2197984, HPA000931: AB_1080100, HPA000982: AB_1080099" "unprognostic (6.90e-2)" "unprognostic (6.47e-2)" "unprognostic (4.27e-2)" "unprognostic (2.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.91e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-2)" "unprognostic (1.35e-1)" "prognostic favorable (1.75e-4)" "prognostic unfavorable (4.23e-4)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.43e-1)" "unprognostic (4.17e-2)" "unprognostic (3.35e-3)" "unprognostic (3.93e-2)" 41.2 35.6 8.0 113.3 7.7 35.1 27.1 5.1 10.2 33.9 5.6 43.4 51.3 27.5 15.1 35.8 25.1 66.6 35.6 11.1 14.7 45.3 66.0 69.1 145.6 18.8 9.4 33.0 40.7 39.0 23.8 28.9 13.4 34.8 40.6 20.0 107.4 24.2 29.8 24.9 41.8 47.5 27.3 114.5 55.7 31.2 17.4 104.3 33.4 29.7 59.0 62.2 25.1 13.2 54.8 58.6 26.8 41.4 105.7 158.8 79.3 82.4 257.1 533.6 595.5 95.1 62.8 21.7 48.1 180.8 173.9 45.9 29.8 62.0 108.6 179.6 24.6 99.0 43.8 47.3 72.2 48.4 58.3 94.7 36.8 100.4 31.0 56.5 63.5 38.4 56.8 103.9 93.6 42.5 38.0 41.1 36.6 34.2 95.3 31.4 71.4 27.9 58.9 70.1 37.9 35.0 100.3 35.7 236.5 37.5 38.6 59.9 56.2 105.1 57.5 90.0 51.4 202.1 330.7 21.0 80.8 40.3 47.8 50.0 143.9 104.9 51.6 191.1 71.4 38.3 129.3 77.4 61.4 31.7 128.2 94.2 203.9 77.3 117.3 28.9 227.8 210.2 8.0 7.7 5.1 10.2 11.1 14.7 18.8 9.4 13.4 27.3 17.4 13.2 46.8 73.7 34.3 14.0 48.8 22.2 17.5 32.3 22.2 13.3 27.6 26.0 44.6 51.5 40.3 53.3 25.0 13.6 48.0 44.4 7.9 47.5 18.5 30.9 43.9 42.1 21.0 15.5 9.0 37.8 53.9 44.1 51.5 39.3 51.4 38.5 28.5 54.1 92.6 3.3 12.2 26.7 16.2 72.0 26.2 5.2 21.8 96.9 17.8 31.9 107.3 13.7 62.8 25.1 11.9 36.0 21.7 29.7 69.4 26.7 24.7 44.0 47.7 19.3 39.5 35.4 31.1 25.4 24.6 28.8 31.3 8.3 78.1 37.9 29.2 26.9 STAT4 ENSG00000138378 "Signal transducer and activator of transcription 4" Q14765 2 191029576-191151596 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 23.0;testis: 29.2" "Cell type enhanced" "Detected in many" "dendritic cells: 139.0;Early spermatids: 275.1;Excitatory neurons: 85.9;Late spermatids: 66.0;NK-cells: 108.1;Plasma cells: 83.8;T-cells: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "NK-cells: 76.6;T-cells: 121.2" "Cell line enhanced" "Detected in some" "Karpas-707: 58.8;U-266/70: 32.9;U-266/84: 12.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA001860, CAB013108" Enhanced NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB013108: , HPA001860: AB_1080104" "unprognostic (3.90e-5)" "unprognostic (1.30e-1)" "unprognostic (4.16e-2)" "unprognostic (6.45e-4)" "unprognostic (3.77e-2)" "unprognostic (4.79e-2)" "unprognostic (3.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.49e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.07e-8)" "unprognostic (2.65e-1)" "unprognostic (6.02e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 4.7 4.0 3.4 11.5 4.4 15.7 3.0 0.1 10.4 1.6 0.1 2.8 4.5 1.9 2.6 1.4 1.6 5.1 23.0 3.8 3.6 4.5 9.5 7.8 18.0 2.1 1.7 1.5 2.2 1.2 15.0 2.6 2.0 1.8 3.4 2.1 2.2 1.3 1.2 1.1 6.9 1.4 0.6 15.5 4.4 29.2 3.4 9.0 2.4 1.0 10.4 5.9 1.8 4.5 0.1 1.7 1.1 0.0 0.0 3.6 0.3 0.6 2.2 0.6 2.2 0.4 0.8 0.0 0.2 2.8 1.6 0.9 0.0 4.7 1.2 0.0 0.8 1.3 0.0 0.0 0.6 0.0 0.1 1.5 2.3 1.1 0.5 0.1 0.0 6.0 0.0 58.8 0.2 0.0 3.5 0.0 0.3 0.0 0.9 0.0 0.0 4.3 0.2 0.1 0.1 1.2 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.1 0.1 1.6 0.0 32.9 12.8 0.0 1.2 0.0 0.1 15.7 0.4 0.1 121.2 0.8 107.3 1.8 71.6 101.2 0.6 1.0 68.1 95.8 2.8 76.6 0.8 9.3 28.1 55.3 3.4 4.4 0.1 10.4 3.8 3.6 2.1 1.7 2.0 0.6 3.4 4.5 2.9 3.2 4.2 2.6 14.5 1.3 0.6 2.9 0.0 0.9 0.9 1.1 20.3 4.3 0.6 1.8 8.4 0.4 139.0 0.5 0.0 0.6 275.1 1.1 0.5 1.2 0.0 10.5 85.9 0.2 2.9 2.9 8.6 0.7 1.3 0.8 1.1 1.1 1.1 0.0 59.4 0.3 0.0 6.3 10.6 66.0 0.3 14.4 5.4 7.5 6.3 0.0 108.1 6.0 2.4 0.1 0.3 0.4 83.8 1.0 0.0 0.8 2.4 0.2 0.0 0.6 3.7 8.3 1.2 0.4 1.7 0.5 137.4 0.1 0.3 0.7 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 NABP1 "DKFZp667M1322, FLJ13624, FLJ22833, hSSB2, MGC111163, OBFC2A, SOSS-B2, SSB2" ENSG00000173559 "Nucleic acid binding protein 1" Q96AH0 2 191678068-191741097 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 36.7" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 452.0;Langerhans cells: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 76.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054978, HPA067802" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm Cytosol "HPA054978: AB_2682660, HPA067802: AB_2685899" "unprognostic (5.43e-2)" "unprognostic (5.33e-2)" "unprognostic (2.80e-1)" "unprognostic (4.73e-2)" "unprognostic (1.48e-1)" "unprognostic (6.89e-2)" "unprognostic (8.07e-4)" "unprognostic (1.33e-1)" "unprognostic (2.89e-2)" "unprognostic (2.99e-1)" "unprognostic (2.82e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (8.20e-7)" "unprognostic (5.64e-2)" "unprognostic (7.50e-2)" "unprognostic (1.48e-1)" "unprognostic (6.02e-2)" 22.0 5.3 2.3 23.2 1.8 5.5 9.8 1.5 2.4 4.7 4.9 5.2 10.0 4.6 0.6 13.2 5.4 7.4 3.9 2.5 2.5 10.5 9.8 21.1 12.4 2.7 2.7 4.5 3.8 0.8 4.3 7.6 2.5 4.4 3.8 1.0 5.2 3.2 2.8 4.4 18.8 3.7 2.2 36.7 4.7 9.2 5.1 6.3 3.2 3.3 11.6 18.4 7.6 3.6 36.2 5.5 1.5 1.6 15.7 16.4 10.2 53.4 31.3 28.6 15.1 30.9 18.7 2.6 43.1 26.3 23.9 11.5 5.7 22.1 29.0 21.2 5.5 18.4 10.8 5.6 14.3 9.8 16.5 22.5 20.3 47.9 23.4 13.8 8.3 4.8 28.7 76.3 31.8 3.3 3.5 10.8 3.6 6.8 31.4 7.1 6.1 16.8 30.2 22.2 2.0 1.3 21.3 7.7 14.1 18.7 2.7 4.7 31.4 28.2 24.6 15.4 33.6 25.2 12.7 9.1 25.1 9.7 6.4 20.0 10.4 8.8 13.2 17.1 19.1 10.8 17.3 13.7 7.3 3.5 8.0 10.7 38.8 6.6 21.5 6.9 28.5 8.5 2.3 1.8 1.5 2.4 2.5 2.5 2.7 2.7 2.5 2.2 5.1 3.6 42.2 214.7 452.0 2.0 66.5 53.0 141.0 15.7 32.5 3.3 33.1 34.3 9.3 8.6 106.2 11.0 2.1 23.6 46.9 79.0 3.9 16.7 212.8 64.9 28.1 34.0 4.2 9.1 3.5 5.7 43.5 62.2 32.1 179.6 139.6 2.2 10.8 8.6 54.9 3.3 3.6 20.2 8.2 113.8 301.8 69.9 10.2 151.3 40.9 18.7 108.8 1.9 18.6 1.5 1.7 30.7 85.7 3.8 43.9 44.8 109.2 22.4 57.6 3.6 6.6 101.5 46.3 25.7 18.4 35.6 45.3 146.3 111.6 12.2 31.7 112.8 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 TMEFF2 "CT120.2, HPP1, TENB2, TPEF, TR" ENSG00000144339 "Transmembrane protein with EGF like and two follistatin like domains 2" Q9UIK5 2 191949043-192194933 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 33.3;prostate: 36.6;seminal vesicle: 13.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 416.1;Inhibitory neurons: 382.0;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 1337.5" "Cancer enriched" "Detected in some" 21 "prostate cancer: 57.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 36.9;LHCN-M2: 107.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015587 Approved "Secreted in male reproductive system" NA NA "Cluster 65: Brain - Ion transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA015587: AB_1858069" "unprognostic (2.12e-3)" "unprognostic (5.37e-1)" "unprognostic (3.10e-1)" "unprognostic (5.89e-7)" "unprognostic (4.96e-2)" "unprognostic (1.27e-1)" "unprognostic (8.82e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-1)" "unprognostic (5.55e-2)" "unprognostic (2.09e-2)" "unprognostic (3.79e-2)" "unprognostic (4.17e-3)" "unprognostic (1.55e-2)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-1)" 0.3 2.3 30.2 0.1 25.8 0.0 0.3 16.0 26.6 0.1 5.8 0.9 0.6 0.0 8.1 1.2 0.1 1.7 1.8 28.5 26.9 0.0 0.0 0.1 0.0 21.5 23.5 0.2 0.0 0.0 0.3 0.0 22.4 36.6 1.5 3.3 0.1 13.3 0.3 0.2 0.6 0.1 16.6 0.0 0.9 0.7 26.3 0.0 0.2 0.6 0.1 0.8 0.5 33.3 0.0 0.9 36.9 0.0 5.6 5.8 0.1 0.1 0.7 1.8 2.2 0.0 0.0 0.0 0.0 10.3 4.5 0.0 2.3 0.0 7.1 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 15.6 0.0 2.0 10.8 9.0 0.1 0.0 0.0 0.0 107.1 0.0 0.0 0.1 2.8 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.2 2.8 0.0 0.0 0.0 7.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.2 25.8 16.0 26.6 28.5 26.9 21.5 23.5 22.4 16.6 26.3 33.3 0.1 0.0 0.0 11.8 0.0 0.1 0.1 0.0 0.0 16.6 0.0 0.0 1.7 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.0 0.0 416.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 102.6 382.0 0.5 0.0 0.0 0.7 2.3 26.4 0.0 0.0 11.2 0.0 0.6 0.0 210.6 1337.5 0.0 0.0 8.6 0.0 5.7 0.1 0.0 0.0 1.6 6.6 24.6 0.6 1.2 2.6 0.3 0.3 0.0 0.4 0.0 0.0 0.1 SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 48.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.8;Microglial cells: 362.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" 8.2 9.7 7.9 6.3 7.4 4.6 7.1 0.0 21.0 10.8 0.0 4.3 3.9 11.0 3.7 3.6 9.5 8.8 4.3 15.8 0.0 8.7 2.0 7.4 8.3 0.1 0.4 7.9 4.8 5.2 1.1 12.8 1.7 19.1 4.2 5.1 3.7 6.7 1.3 7.0 4.0 7.7 1.4 18.3 5.0 9.3 9.9 10.6 48.4 3.1 7.6 6.3 2.1 5.8 7.3 27.1 46.8 13.0 9.5 21.1 24.3 34.8 16.4 16.1 8.1 38.4 26.4 10.4 51.3 19.6 12.4 10.4 28.6 31.6 19.9 5.4 21.8 11.7 37.1 34.0 10.8 45.4 4.9 12.9 5.1 17.7 20.2 56.9 37.3 10.5 34.9 14.3 26.7 7.3 12.7 14.0 53.8 44.1 18.8 28.9 16.6 27.0 74.8 12.7 17.5 24.7 34.4 65.1 18.7 81.2 11.2 26.5 36.1 28.7 33.6 19.0 18.7 4.6 3.7 6.3 24.5 19.9 29.9 41.5 4.7 3.7 7.5 4.4 6.1 12.3 6.8 6.7 6.4 15.8 6.0 7.8 0.8 21.7 3.3 32.8 7.6 2.6 7.9 7.4 0.0 21.0 15.8 0.0 0.1 0.4 1.7 1.4 9.9 5.8 72.1 3.2 12.8 40.8 42.0 25.6 12.1 51.3 13.1 23.0 16.9 23.1 7.6 5.7 33.2 36.8 8.4 49.3 60.2 4.3 1.9 17.7 28.5 13.2 48.7 75.4 15.6 26.9 170.8 11.3 66.0 35.3 11.2 16.5 13.3 25.7 26.4 2.8 24.5 8.4 78.3 5.9 26.4 20.7 27.1 16.0 19.0 31.8 7.2 362.6 16.2 17.0 20.6 49.3 49.5 24.3 2.8 18.8 21.3 20.1 4.5 14.7 9.5 20.0 13.1 41.9 29.1 61.3 33.6 7.5 20.5 23.4 35.4 30.8 6.2 7.8 DNAH7 KIAA0944 ENSG00000118997 "Dynein axonemal heavy chain 7" Q8WXX0 2 195737703-196068837 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.9;choroid plexus: 29.8" "Cell type enhanced" "Detected in many" "Astrocytes: 197.2;Cone photoreceptor cells: 70.9;Early spermatids: 59.3;Endometrial ciliated cells: 103.5;Excitatory neurons: 93.0;Respiratory ciliated cells: 139.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 5.9;RPTEC TERT1: 2.8" "Region enhanced" "Detected in many" "midbrain: 4.4" "HPA034724, HPA044070" Enhanced Supported Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA034724: AB_10670977, HPA044070: AB_2678798" "unprognostic (1.71e-1)" "unprognostic (2.81e-2)" "unprognostic (2.65e-2)" "unprognostic (1.04e-2)" "unprognostic (3.56e-1)" "unprognostic (1.58e-2)" "unprognostic (6.74e-3)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-2)" "unprognostic (1.71e-1)" "unprognostic (6.25e-3)" "unprognostic (2.24e-1)" "unprognostic (7.76e-2)" "unprognostic (2.52e-3)" "unprognostic (3.98e-2)" 0.3 1.0 8.2 0.2 7.9 0.0 0.6 3.6 10.1 2.5 29.8 0.7 0.1 0.8 1.7 0.2 9.8 0.6 0.4 8.0 7.1 3.4 0.3 2.3 0.1 10.2 12.9 0.5 2.6 2.0 7.2 0.1 8.0 1.1 0.5 8.9 0.8 0.9 0.0 0.2 0.7 0.3 7.6 0.1 0.6 10.8 9.0 0.1 3.2 0.0 0.2 0.2 0.3 6.7 0.3 1.3 0.3 0.1 0.7 0.4 0.1 0.1 0.8 0.3 0.3 0.2 1.0 0.0 0.3 0.3 1.0 0.0 0.0 0.2 0.2 0.0 0.8 0.0 1.7 0.4 0.1 0.0 0.1 0.2 0.2 1.1 0.2 1.7 0.0 0.0 0.3 1.8 0.5 1.4 0.0 0.0 0.3 0.7 5.9 0.0 0.3 0.5 2.8 0.2 0.6 1.0 0.3 0.2 0.1 0.1 0.5 0.1 0.0 0.7 0.2 1.1 0.3 1.4 1.4 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 8.2 7.9 3.6 10.1 8.0 7.1 10.2 12.9 8.0 7.6 9.0 6.7 0.5 0.0 6.1 197.2 0.0 0.9 1.2 3.3 0.0 1.9 2.1 1.3 1.3 0.0 12.3 1.8 70.9 0.0 0.1 4.4 0.0 2.9 59.3 103.5 2.8 1.8 0.0 0.0 93.0 0.7 0.0 1.0 1.5 3.0 0.0 0.8 0.7 0.0 0.1 1.7 25.6 1.0 4.1 0.0 1.2 27.8 0.6 0.4 1.8 13.1 0.0 2.9 0.0 5.5 2.2 0.6 0.2 1.5 0.1 1.8 3.7 2.6 139.5 36.8 0.0 2.1 1.1 28.0 5.7 0.0 1.3 0.1 0.2 0.8 0.7 0.7 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 376.2;lymphoid tissue: 113.3" "Cell type enhanced" "Detected in many" "B-cells: 229.3;dendritic cells: 267.7;granulocytes: 195.1;Langerhans cells: 201.3;Macrophages: 198.9;Plasma cells: 191.8;T-cells: 342.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 122.3;HMC-1: 118.9;Karpas-707: 111.6;U-698: 132.1" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 28.2 8.9 2.1 67.0 2.9 376.2 21.5 3.7 5.3 24.2 3.3 19.1 27.8 5.4 1.8 11.9 5.8 20.4 4.6 4.1 3.3 6.5 8.5 23.6 113.3 3.1 2.0 2.2 12.7 2.1 3.0 16.7 3.2 10.5 17.5 0.4 17.0 5.7 2.4 11.2 40.1 16.8 2.2 56.9 20.1 9.5 4.0 60.9 7.2 3.5 111.1 24.4 5.2 2.9 11.0 7.5 11.2 4.2 47.7 18.1 12.4 25.7 38.4 27.7 28.5 22.8 3.9 122.3 23.1 14.8 7.3 7.4 4.7 11.1 33.4 21.8 12.7 11.6 9.1 2.2 14.2 47.0 118.9 23.1 10.9 34.3 17.7 39.2 11.5 28.5 9.1 111.6 69.4 5.9 61.6 106.0 6.3 19.9 17.2 10.1 67.5 37.4 16.3 25.6 4.2 4.2 6.6 6.4 5.4 17.2 4.3 24.3 14.0 26.8 13.1 19.3 14.7 45.5 78.9 132.1 20.2 15.9 12.1 165.1 74.3 163.1 43.7 81.3 55.4 49.2 77.0 52.8 53.0 58.6 98.6 82.4 236.7 40.8 113.1 37.7 73.8 89.3 2.1 2.9 3.7 5.3 4.1 3.3 3.1 2.0 3.2 2.2 4.0 2.9 23.3 89.8 74.0 48.3 229.3 59.9 27.1 15.1 10.8 0.9 28.9 15.2 2.6 12.8 42.5 11.0 0.0 7.9 267.7 54.0 3.9 6.6 6.8 15.3 14.1 11.3 3.0 68.8 3.4 2.8 24.0 27.2 38.2 26.5 195.1 47.4 5.3 2.4 26.1 0.0 3.1 13.9 18.3 151.1 201.3 3.6 5.6 198.9 58.7 11.2 158.0 0.6 118.4 17.6 0.7 10.9 41.6 4.5 191.8 34.3 80.7 2.5 26.9 0.3 6.6 49.7 19.7 41.1 26.3 16.4 63.4 5.1 342.5 22.6 13.2 53.8 HECW2 "KIAA1301, NEDL2" ENSG00000138411 "HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2" Q9P2P5 2 196189099-196593684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 331.5;Hepatic stellate cells: 99.2;Inhibitory neurons: 375.4;Oligodendrocyte precursor cells: 143.2;Oligodendrocytes: 460.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.7;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "granulocytes: 4.7;monocytes: 3.7" "Cell line enhanced" "Detected in many" "HDLM-2: 30.1;hTEC/SVTERT24-B: 16.3;HUVEC TERT2: 20.9;SCLC-21H: 31.6;TIME: 26.3;U-138 MG: 21.7" "Low region specificity" "Detected in all" HPA034609 Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA034609: AB_10669993" "unprognostic (2.65e-2)" "unprognostic (3.89e-1)" "unprognostic (1.42e-1)" "unprognostic (9.00e-3)" "unprognostic (2.55e-1)" "unprognostic (4.28e-2)" "unprognostic (7.63e-3)" "unprognostic (1.23e-1)" "unprognostic (2.61e-2)" "unprognostic (7.05e-2)" "unprognostic (4.16e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (5.18e-5)" "unprognostic (8.05e-3)" "unprognostic (5.20e-2)" "unprognostic (1.49e-1)" "unprognostic (4.48e-2)" 4.1 1.5 2.4 1.2 3.5 0.1 1.7 4.4 6.1 2.2 0.0 0.4 0.4 0.8 0.3 3.1 3.5 2.1 8.1 3.3 0.0 1.6 2.7 5.3 2.0 1.1 0.8 0.2 0.6 4.3 1.2 7.4 2.1 0.4 0.4 2.7 0.9 0.5 1.4 0.8 0.5 1.3 0.0 6.0 0.9 3.5 1.7 0.8 3.8 3.5 2.4 1.0 0.6 8.2 0.1 1.4 2.3 0.0 1.4 4.2 1.6 2.7 7.3 2.1 2.6 0.3 0.1 1.4 0.5 13.4 3.3 3.2 0.9 0.1 4.5 30.1 1.6 0.0 2.3 0.2 0.2 0.5 0.3 1.0 1.3 16.3 5.7 4.1 20.9 0.0 0.2 0.1 6.7 1.8 0.0 0.7 2.5 0.2 1.0 0.0 0.5 0.0 0.1 0.0 31.6 2.5 2.0 0.5 0.0 0.4 0.1 0.2 26.3 21.7 1.4 4.6 0.7 0.2 0.0 1.3 5.4 0.1 0.2 0.1 0.3 0.8 0.0 1.1 0.0 0.4 0.0 0.0 0.4 0.5 0.0 0.0 4.7 0.0 3.7 0.0 0.0 0.1 2.4 3.5 4.4 6.1 3.3 0.0 1.1 0.8 2.1 0.0 1.7 8.2 61.2 0.0 12.1 12.7 3.6 2.2 0.3 0.1 3.4 9.5 1.1 0.8 18.7 0.0 0.1 0.0 0.0 0.2 0.7 0.6 0.0 0.1 11.1 0.4 1.6 34.2 2.4 0.0 331.5 0.0 0.3 4.2 0.5 0.3 1.3 4.9 99.2 1.5 0.1 0.0 375.4 0.6 0.0 7.2 3.0 5.3 0.0 1.4 3.6 14.0 1.2 12.0 0.0 143.2 460.7 0.1 0.0 2.6 3.4 0.4 0.0 0.1 1.0 1.1 0.0 1.2 2.2 0.5 6.1 9.2 1.6 0.1 1.4 0.7 0.1 0.6 CCDC150 FLJ39660 ENSG00000144395 "Coiled-coil domain containing 150" Q8NCX0 2 196639554-196763490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 2.6;testis: 4.9" "Cell type enhanced" "Detected in many" "Early spermatids: 54.5;Granulosa cells: 16.5;Late spermatids: 20.9;Oligodendrocytes: 16.4;Spermatocytes: 32.2" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA048104 Uncertain Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "HPA048104: AB_2680264" "unprognostic (1.92e-1)" "unprognostic (3.75e-1)" "unprognostic (2.95e-1)" "unprognostic (2.58e-4)" "unprognostic (9.88e-2)" "unprognostic (1.42e-3)" "unprognostic (1.59e-2)" "unprognostic (1.62e-1)" "unprognostic (5.91e-4)" "unprognostic (2.01e-2)" "unprognostic (3.16e-2)" "unprognostic (9.17e-3)" "unprognostic (5.66e-4)" "unprognostic (7.29e-2)" "unprognostic (1.99e-2)" "unprognostic (4.35e-2)" "unprognostic (2.69e-5)" 0.1 0.0 0.2 0.2 0.2 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 2.6 1.2 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 4.9 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.2 1.0 0.3 4.4 2.8 0.1 0.3 1.9 1.0 0.5 0.7 1.9 1.5 0.9 0.6 0.5 0.7 0.6 1.3 1.7 0.8 1.9 4.2 2.4 1.4 2.4 2.5 0.0 0.9 0.6 0.0 0.1 1.0 0.5 0.2 0.5 1.5 2.0 1.8 0.5 0.5 0.8 1.3 2.6 0.3 1.0 1.8 0.6 0.6 0.3 0.4 4.6 0.9 0.7 0.4 0.2 2.2 0.7 0.5 0.9 1.5 1.4 1.4 0.9 0.8 0.8 1.4 0.5 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.3 0.1 0.1 0.2 0.2 0.2 0.2 0.2 0.2 1.5 3.2 1.7 2.3 1.0 1.5 2.2 0.2 0.0 3.6 0.6 1.3 1.5 1.5 0.1 0.0 2.1 2.2 0.7 1.4 1.9 0.3 54.5 2.1 1.7 2.6 0.0 2.1 1.1 0.4 2.0 2.3 1.5 3.8 3.8 16.5 1.4 3.8 1.3 1.7 3.0 1.4 0.0 1.3 2.5 20.9 1.5 1.3 7.2 0.0 0.5 1.1 2.1 2.0 16.4 0.4 1.2 1.9 2.4 1.3 0.7 12.5 2.5 1.3 0.0 4.0 2.3 32.2 14.8 2.0 1.0 0.7 1.2 2.8 1.7 1.3 GTF3C3 "TFIIIC102, TFiiiC2-102" ENSG00000119041 "General transcription factor IIIC subunit 3" Q9Y5Q9 2 196763035-196799725 "Predicted intracellular proteins, Predicted membrane proteins" Transcription DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069179 Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear membrane" "HPA069179: AB_2686099" "unprognostic (1.44e-1)" "unprognostic (2.63e-2)" "unprognostic (1.89e-1)" "unprognostic (4.52e-2)" "unprognostic (5.88e-2)" "unprognostic (3.64e-2)" "prognostic unfavorable (1.26e-6)" "unprognostic (1.92e-1)" "unprognostic (9.28e-2)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (5.62e-2)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (2.72e-1)" "unprognostic (1.70e-1)" "unprognostic (3.08e-2)" 11.0 10.9 18.1 9.6 20.4 36.8 19.5 25.1 23.1 10.9 23.8 10.8 10.2 12.2 15.1 11.4 11.9 19.6 10.0 19.8 19.9 9.5 12.9 10.5 18.8 21.7 19.0 13.8 13.1 13.6 9.0 12.5 25.9 10.2 13.1 18.6 9.7 10.0 13.6 20.9 10.8 14.3 17.9 13.8 12.1 13.9 19.5 13.4 15.1 7.3 10.9 11.6 9.4 31.8 14.4 19.2 28.4 22.2 13.1 19.4 28.0 26.2 16.3 24.7 25.0 41.4 23.0 29.8 15.9 15.7 24.1 19.2 24.4 23.3 28.7 35.0 26.6 37.2 59.9 38.6 21.8 32.8 28.9 25.8 21.4 17.8 25.0 21.9 22.6 25.7 45.6 54.6 14.9 34.0 28.6 29.2 16.9 16.9 29.3 24.4 20.7 19.8 17.6 43.2 22.6 20.5 16.7 14.6 17.8 35.9 15.4 21.1 15.0 21.2 15.1 16.7 19.3 26.0 34.4 22.2 21.8 24.4 16.9 8.4 4.7 4.4 3.9 3.1 3.5 4.8 3.5 4.0 2.8 6.8 4.2 4.0 4.4 4.8 5.8 4.3 4.8 2.3 18.1 20.4 25.1 23.1 19.8 19.9 21.7 19.0 25.9 17.9 19.5 31.8 17.4 22.4 16.0 19.2 11.6 4.0 12.2 16.6 10.2 18.1 8.8 8.8 35.8 7.2 21.4 14.7 18.8 15.3 18.1 7.7 13.7 12.4 4.4 18.2 17.4 17.0 12.5 19.1 24.7 12.3 12.6 12.9 11.2 13.3 14.0 24.7 12.8 8.2 13.5 0.0 29.8 10.1 16.2 12.7 5.0 4.6 13.4 11.8 7.2 27.2 22.0 12.5 9.2 23.1 38.5 14.7 6.4 10.9 16.3 8.4 12.9 10.9 37.2 15.6 6.6 10.1 13.6 44.7 24.8 11.6 5.5 15.7 12.2 18.2 11.9 9.4 C2orf66 UNQ6411 ENSG00000187944 "Chromosome 2 open reading frame 66" 2 196804417-196809355 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "adrenal gland: 3.9;brain: 5.1;pituitary gland: 3.7" "Cell type enriched" "Detected in some" 7 "Early spermatids: 36.9" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 9.0;RT4: 2.2;TIME: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA020869 Uncertain Uncertain Nucleoplasm,Cytosol "Secreted - unknown location" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 36: HEL - Hemostasis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm Cytosol "HPA020869: AB_1851545" "unprognostic (1.19e-1)" "unprognostic (4.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (1.61e-2)" "unprognostic (6.80e-3)" "unprognostic (3.05e-2)" "unprognostic (1.95e-1)" "unprognostic (4.10e-3)" "unprognostic (4.54e-4)" "unprognostic (1.98e-1)" "unprognostic (1.75e-5)" "unprognostic (1.84e-1)" "unprognostic (2.30e-1)" "unprognostic (1.38e-2)" "unprognostic (1.86e-2)" 2.8 3.9 2.1 0.2 1.8 0.1 0.4 1.4 2.2 0.0 1.7 0.3 0.0 0.1 0.4 0.2 0.6 0.3 0.5 2.0 4.2 0.2 0.1 0.3 0.0 2.3 5.1 0.3 0.4 0.1 3.7 0.0 2.9 0.3 0.1 1.8 0.1 0.1 0.0 1.2 0.3 0.0 1.5 0.1 0.2 1.5 2.8 0.1 0.1 0.0 0.1 0.3 0.2 1.6 0.0 0.1 0.2 0.8 0.2 0.2 0.0 0.3 0.2 0.2 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.4 9.0 0.3 0.1 0.0 0.1 0.8 0.2 1.2 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.0 0.4 2.2 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.1 2.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.8 1.4 2.2 2.0 4.2 2.3 5.1 2.9 1.5 2.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.9 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 PGAP1 "Bst1, FLJ12377, SPG67" ENSG00000197121 "Post-GPI attachment to proteins inositol deacylase 1" Q75T13 2 196833004-196927796 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 19.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 89.6;Inhibitory neurons: 104.5;Oligodendrocyte precursor cells: 130.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.21e-1)" "unprognostic (9.15e-2)" "unprognostic (5.89e-2)" "unprognostic (3.82e-2)" "unprognostic (1.81e-1)" "unprognostic (5.55e-3)" "unprognostic (2.50e-2)" "unprognostic (6.95e-2)" "unprognostic (6.51e-2)" "unprognostic (1.41e-2)" "unprognostic (2.59e-3)" "unprognostic (9.61e-2)" "unprognostic (7.16e-3)" "unprognostic (1.21e-1)" "unprognostic (7.88e-2)" "unprognostic (9.03e-3)" "unprognostic (1.91e-2)" 3.9 8.4 10.2 1.1 11.7 2.0 3.8 8.9 12.1 3.5 4.6 3.0 3.7 3.0 3.1 3.5 2.8 1.5 3.2 7.9 19.2 1.7 1.2 4.5 1.1 6.8 15.1 9.3 4.4 2.8 9.2 3.3 7.3 3.2 2.8 13.0 2.2 2.2 1.4 12.3 4.3 2.2 4.4 1.4 2.0 1.5 17.8 1.7 2.1 1.4 1.1 3.0 3.9 5.8 1.5 0.6 15.2 8.3 6.8 4.1 2.5 1.9 1.4 1.1 1.3 0.8 1.6 1.8 2.4 2.8 2.4 2.8 4.0 4.3 1.7 9.0 5.2 1.2 4.0 4.1 1.8 2.6 2.0 3.0 3.0 1.9 2.2 7.9 6.6 5.9 0.3 3.0 4.2 0.6 2.4 3.3 7.1 2.4 3.5 3.7 3.8 0.5 2.4 13.8 12.6 10.0 1.3 1.9 2.4 9.0 1.9 1.0 7.6 5.1 2.2 2.5 2.6 2.7 1.5 2.4 3.9 1.2 5.1 0.1 0.1 0.1 0.2 0.0 0.2 0.2 0.7 0.7 0.1 0.2 0.6 0.5 0.2 0.1 0.0 0.0 0.9 0.0 10.2 11.7 8.9 12.1 7.9 19.2 6.8 15.1 7.3 4.4 17.8 5.8 9.3 3.2 2.6 37.9 12.7 34.4 13.5 21.4 30.1 43.3 5.4 5.6 6.8 2.8 6.9 25.8 25.0 37.4 4.6 5.8 0.0 1.4 8.3 11.9 14.5 9.7 38.9 3.2 89.6 3.7 9.1 15.8 14.3 4.3 4.5 8.8 4.2 4.4 6.2 13.5 104.5 13.6 8.2 1.9 14.9 4.8 14.3 3.0 7.2 23.4 1.3 17.5 3.1 130.2 58.7 0.9 8.2 15.8 8.2 11.4 12.4 1.6 16.7 41.1 6.6 12.0 33.8 11.0 8.2 23.4 30.0 15.9 18.5 8.1 24.0 11.9 ANKRD44 PP6-ARS-B ENSG00000065413 "Ankyrin repeat domain 44" Q8N8A2 2 196967017-197311173 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 36.5" "Cell type enhanced" "Detected in many" "B-cells: 153.3;Microglial cells: 390.7;NK-cells: 146.2;Oligodendrocyte precursor cells: 174.9;Oligodendrocytes: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 46.4;HMC-1: 33.8;Karpas-707: 25.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030122, HPA056549" Approved Approved "Nuclear speckles,Mitochondria" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" Mitochondria "Nuclear speckles" "HPA030122: AB_10600980, HPA056549: AB_2683170" "unprognostic (3.64e-1)" "unprognostic (1.70e-2)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (2.63e-1)" "unprognostic (7.04e-5)" "unprognostic (1.97e-2)" "unprognostic (1.58e-3)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (8.25e-3)" "unprognostic (1.33e-1)" "unprognostic (1.33e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-2)" 5.8 6.4 8.0 24.6 10.8 17.4 4.1 8.9 9.3 8.1 5.7 5.8 3.8 4.9 2.8 3.2 3.8 8.4 4.2 6.8 10.4 3.3 4.9 11.6 36.5 12.7 10.8 3.2 3.7 4.1 3.9 7.6 13.2 4.4 5.5 3.3 4.0 5.0 2.2 3.6 11.5 6.1 10.0 23.0 6.8 5.7 11.7 28.3 3.2 2.2 33.2 6.8 6.2 14.6 1.9 1.1 2.8 2.9 6.2 2.5 0.6 4.1 1.8 2.1 1.9 0.7 1.0 15.4 1.9 3.5 3.9 0.2 1.0 0.8 1.7 46.4 3.7 0.5 5.6 0.3 0.4 11.4 33.8 1.3 0.5 2.1 0.1 3.1 2.9 3.8 2.6 25.1 3.2 2.6 5.4 9.7 0.4 0.6 2.8 9.7 3.1 20.3 5.4 1.4 2.8 12.2 1.4 1.0 12.0 2.1 1.5 11.0 15.0 7.1 4.2 2.2 3.0 6.2 8.0 19.6 5.0 14.0 4.5 55.0 19.6 45.3 24.5 19.5 23.3 23.5 18.2 21.3 19.2 28.6 20.9 25.2 68.7 25.0 25.2 12.6 19.0 15.1 8.0 10.8 8.9 9.3 6.8 10.4 12.7 10.8 13.2 10.0 11.7 14.6 8.4 16.0 23.9 79.7 153.3 3.4 4.5 0.4 2.2 9.9 4.4 3.9 9.3 20.0 8.0 11.0 4.2 5.9 90.6 0.6 1.9 4.0 14.0 10.7 6.7 10.2 2.4 12.8 32.6 4.6 0.8 9.7 8.2 15.5 53.8 4.8 49.2 8.9 18.5 3.3 126.4 1.9 0.0 64.2 34.9 17.5 15.5 72.5 37.4 390.7 84.1 8.0 146.2 174.9 199.5 5.0 2.6 17.7 70.4 3.9 2.9 1.5 10.6 10.4 19.7 15.5 16.4 2.9 3.4 5.2 3.7 1.4 123.0 4.3 1.8 4.9 SF3B1 "Hsh155, Prp10, PRPF10, SAP155, SF3b155" ENSG00000115524 "Splicing factor 3b subunit 1" O75533 2 197388515-197435079 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050275 Approved Enhanced "Nuclear speckles" NA NA 94000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "HPA050275: AB_2681071" "unprognostic (6.86e-2)" "unprognostic (2.78e-1)" "unprognostic (2.14e-1)" "unprognostic (3.51e-1)" "unprognostic (4.42e-2)" "unprognostic (1.25e-3)" "unprognostic (2.44e-3)" "unprognostic (3.31e-3)" "unprognostic (1.25e-2)" "unprognostic (2.20e-1)" "unprognostic (6.79e-2)" "unprognostic (1.78e-2)" "unprognostic (2.57e-2)" "unprognostic (9.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (3.41e-2)" 183.8 173.9 101.7 132.7 112.4 304.8 180.7 120.5 126.1 222.8 136.8 170.9 110.4 195.8 200.0 136.8 183.8 123.2 135.7 98.2 100.8 135.4 168.5 162.8 203.0 105.7 101.9 226.5 200.7 154.9 147.8 165.3 111.0 163.2 147.3 138.4 180.4 133.2 172.4 156.5 231.6 116.5 107.5 287.8 169.2 91.4 104.9 221.9 167.8 144.8 199.3 154.4 167.1 135.8 134.9 105.4 288.6 155.9 222.8 219.2 237.8 172.6 196.7 163.2 205.9 233.0 147.2 247.5 116.6 193.1 165.8 133.7 273.4 151.2 271.8 196.5 154.8 237.5 257.4 294.3 155.4 270.1 198.6 232.1 163.0 175.9 209.3 278.6 205.9 171.0 210.2 174.0 192.3 134.2 251.1 285.6 231.4 167.5 163.8 234.4 197.9 182.9 245.8 286.4 154.2 186.7 174.7 118.2 139.2 345.1 115.2 242.5 186.8 126.9 109.4 123.3 145.8 168.7 238.8 342.0 123.7 174.8 146.5 49.8 50.4 57.5 54.5 51.7 55.4 46.1 46.2 50.9 60.5 44.1 48.7 49.2 60.8 56.7 52.5 37.5 71.3 56.2 101.7 112.4 120.5 126.1 98.2 100.8 105.7 101.9 111.0 107.5 104.9 135.8 175.6 179.5 222.9 92.4 187.4 119.0 172.0 127.1 125.7 103.4 96.4 83.3 129.2 72.9 194.0 92.0 73.0 116.8 224.1 90.1 56.7 104.8 9.2 123.9 191.0 143.1 110.5 109.0 55.5 94.8 102.3 151.6 132.0 179.0 246.9 171.1 107.1 74.4 100.6 94.2 59.7 108.1 89.5 124.7 144.1 20.6 120.2 166.1 76.5 75.9 163.9 111.1 116.4 87.0 121.1 112.0 68.3 104.6 195.6 103.8 84.2 70.5 221.5 98.5 118.3 159.5 227.9 104.6 100.5 94.3 118.8 142.7 216.2 119.4 91.4 156.1 COQ10B FLJ13448 ENSG00000115520 "Coenzyme Q10B" Q9H8M1 2 197453423-197475308 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046057 Approved Approved Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "HPA046057: AB_2679518" "unprognostic (9.17e-2)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (1.82e-3)" "unprognostic (8.28e-3)" "unprognostic (5.76e-3)" "unprognostic (4.55e-1)" "unprognostic (2.93e-1)" "unprognostic (7.18e-2)" "unprognostic (6.00e-2)" "unprognostic (4.13e-2)" "unprognostic (3.99e-1)" "unprognostic (2.87e-3)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (3.13e-3)" 25.0 37.7 15.2 17.4 15.4 46.8 19.1 16.2 19.0 15.7 18.6 19.7 16.2 16.5 15.9 18.8 13.0 26.1 34.3 16.2 17.1 28.6 35.1 17.6 19.8 16.3 16.5 10.5 15.9 29.6 14.3 21.6 16.8 17.5 20.3 18.3 12.7 17.6 12.8 12.7 15.4 24.9 16.7 18.8 18.3 10.7 17.3 17.3 21.1 19.1 19.4 31.0 12.2 17.9 15.7 14.7 10.5 18.8 49.6 35.3 24.6 40.2 57.5 42.3 46.8 30.0 18.5 14.7 33.4 32.5 52.5 14.1 15.3 21.3 47.8 29.0 13.2 21.0 19.1 35.4 41.5 17.0 46.6 39.5 32.8 40.3 28.5 22.9 23.3 20.9 17.9 38.1 40.9 20.4 18.6 26.4 16.2 18.4 30.0 13.9 15.7 19.4 45.7 42.0 6.8 13.1 18.4 23.9 52.0 37.2 17.1 23.9 24.6 41.4 14.4 46.8 29.3 36.0 55.0 16.5 51.7 16.3 32.7 70.8 30.0 57.5 43.7 35.5 49.2 32.8 41.4 43.6 26.4 25.2 43.0 44.4 90.7 34.1 42.8 16.7 56.5 38.0 15.2 15.4 16.2 19.0 16.2 17.1 16.3 16.5 16.8 16.7 17.3 17.9 73.2 19.2 19.9 7.2 54.4 105.5 106.5 55.7 44.9 30.2 42.3 24.3 29.0 24.3 42.3 40.5 41.7 32.7 62.5 43.7 129.1 44.9 38.7 35.8 34.5 48.9 26.9 38.3 12.4 46.1 43.7 67.6 33.1 43.5 60.3 12.2 22.9 36.7 32.0 63.9 11.8 44.3 57.0 23.8 74.6 20.7 20.5 44.3 71.2 7.5 29.2 56.7 49.4 7.1 16.0 54.2 36.3 30.5 45.1 65.6 30.0 73.7 41.7 36.6 46.0 60.8 71.0 20.9 39.4 29.0 106.6 173.9 70.9 33.7 19.1 100.0 HSPD1 "GroEL, HSP60, SPG13" ENSG00000144381 "Heat shock protein family D (Hsp60) member 1" P10809 2 197486584-197516737 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, Isomerase" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 790.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 1737.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001523, CAB002775, HPA050025, CAB072816" Supported Enhanced Mitochondria NA NA 18000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Mitochondria "CAB002775: , CAB072816: , HPA001523: AB_1079028, HPA050025: AB_2680995" "unprognostic (2.79e-2)" "unprognostic (1.72e-2)" "unprognostic (5.21e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.59e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (2.25e-4)" "unprognostic (3.51e-2)" "unprognostic (9.91e-2)" "unprognostic (8.63e-3)" "unprognostic (3.47e-2)" "unprognostic (7.83e-3)" "unprognostic (5.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (4.10e-2)" 179.4 790.6 188.6 128.3 191.6 110.6 168.8 204.9 401.9 96.9 217.8 170.0 158.1 90.8 89.3 124.5 132.6 69.1 145.0 184.3 198.6 374.9 462.6 136.6 149.2 199.6 198.5 167.6 219.0 159.2 116.0 148.6 205.3 104.5 195.1 71.8 93.9 93.6 162.7 83.3 148.7 104.5 195.1 94.6 155.4 57.6 198.6 99.3 138.7 176.7 172.7 144.6 92.3 201.4 559.7 650.1 541.3 496.9 373.6 389.2 786.5 573.2 304.7 686.1 495.6 2219.1 326.2 1724.4 730.0 304.1 834.2 538.4 2232.9 633.2 943.0 417.0 888.2 1209.8 984.8 2562.8 353.2 1331.4 349.1 445.5 717.1 599.5 1053.2 471.4 542.6 919.1 1535.3 606.8 501.7 690.4 853.6 1304.2 1086.4 735.2 1424.9 1000.1 679.7 1235.5 709.5 539.7 716.5 400.8 582.0 608.5 771.0 1116.3 425.0 789.4 242.2 405.8 570.4 532.8 910.0 331.1 861.4 1399.5 485.7 795.3 456.7 12.1 52.3 11.4 36.4 81.8 71.7 63.8 59.6 54.3 84.6 54.0 81.0 70.3 11.0 62.6 72.1 49.4 51.8 70.6 188.6 191.6 204.9 401.9 184.3 198.6 199.6 198.5 205.3 195.1 198.6 201.4 216.4 166.7 172.5 38.8 220.4 246.6 1737.2 247.5 264.0 75.8 216.0 263.1 239.2 195.9 287.9 79.1 256.5 825.7 197.7 213.7 375.6 235.0 6.2 322.2 304.5 233.9 274.6 241.6 31.9 145.9 419.8 356.0 215.6 445.2 299.5 407.1 63.1 312.5 328.0 95.9 47.2 302.2 166.8 88.6 479.3 12.8 130.5 381.9 163.7 30.0 138.5 125.7 68.0 20.6 35.6 171.4 163.2 113.6 322.9 705.9 160.1 797.1 328.6 117.1 85.5 199.0 471.7 88.5 106.0 262.4 207.1 1001.2 467.2 1017.4 512.1 861.5 HSPE1 "CPN10, EPF, GroES, HSP10" ENSG00000115541 "Heat shock protein family E (Hsp10) member 1" P61604 2 197500140-197503449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1077.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1907.6;Proximal tubular cells: 1978.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 4135.5" "Low region specificity" "Detected in all" "CAB017366, HPA038755, HPA048272" Supported NA Yes 2500000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "CAB017366: AB_10998950, HPA038755: AB_2676190, HPA048272: AB_2680336" "unprognostic (2.75e-2)" "unprognostic (6.89e-2)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (1.98e-1)" "unprognostic (1.85e-2)" "unprognostic (5.83e-3)" "unprognostic (4.14e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-3)" "unprognostic (1.39e-2)" "unprognostic (6.21e-3)" "unprognostic (2.63e-1)" "unprognostic (4.51e-2)" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (7.08e-3)" 152.1 709.5 383.2 143.9 387.5 116.8 212.7 410.3 1077.6 122.3 402.1 257.2 164.9 84.3 213.0 132.9 131.4 97.4 208.0 383.7 400.8 410.7 662.7 111.0 154.5 400.9 394.7 130.1 112.6 173.0 125.5 164.0 399.9 137.9 246.3 85.8 121.9 114.8 181.4 80.5 168.2 116.8 403.6 86.5 130.5 58.7 391.2 144.8 104.5 213.1 207.9 216.6 85.5 440.8 593.1 926.1 675.1 521.5 560.5 314.0 905.5 586.2 307.9 620.8 577.3 2796.6 504.6 1079.2 782.2 333.8 1542.1 510.4 1895.0 681.2 782.0 512.3 874.7 1099.8 1789.0 4135.5 239.0 1503.6 497.2 382.4 532.1 577.8 297.6 392.7 631.0 720.9 1588.2 338.0 481.1 1027.2 1107.2 1706.9 1077.5 985.2 1513.4 747.6 568.2 1388.5 967.4 1028.3 581.5 375.1 546.4 713.9 545.5 1588.2 287.1 881.7 355.7 466.1 643.3 501.0 1019.4 427.8 1016.0 1758.3 515.6 726.7 640.6 33.2 95.5 24.4 166.3 174.5 216.3 287.1 223.6 210.1 156.6 221.8 251.7 264.1 12.6 200.3 143.1 263.4 198.7 176.0 383.2 387.5 410.3 1077.6 383.7 400.8 400.9 394.7 399.9 403.6 391.2 440.8 341.6 195.5 160.2 0.0 380.6 435.1 1907.6 690.4 301.7 90.7 393.6 511.2 355.6 381.8 363.3 195.0 250.2 839.3 334.4 553.8 911.7 354.0 22.3 520.7 291.3 296.3 440.3 233.1 0.0 231.2 634.0 370.0 274.2 493.3 324.6 215.7 94.6 1092.0 517.2 63.9 0.0 605.0 427.2 150.6 616.4 36.1 216.6 534.4 409.1 0.0 214.2 204.2 133.9 0.0 0.0 285.3 466.2 141.8 323.4 830.7 562.1 1978.2 475.8 160.2 131.5 283.6 642.5 140.0 241.9 381.2 371.8 976.7 685.9 791.7 775.5 1111.7 HSPE1-MOB4 ENSG00000270757 "HSPE1-MOB4 readthrough" 2 197500413-197550726 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 2.6;Astrocytes: 1.6;Excitatory neurons: 1.5;Inhibitory neurons: 1.7;Oligodendrocytes: 1.6;Respiratory ciliated cells: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038755, HPA044125, HPA048272" Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 11: Alveolar cells - Smell perception" "HPA038755: AB_2676190, HPA044125: AB_2678822, HPA048272: AB_2680336" "unprognostic (7.69e-3)" "unprognostic (4.73e-2)" "unprognostic (2.53e-2)" "unprognostic (9.15e-2)" "unprognostic (8.80e-2)" "unprognostic (3.50e-1)" "unprognostic (4.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "unprognostic (7.91e-2)" "unprognostic (2.48e-1)" "unprognostic (2.32e-1)" "unprognostic (4.12e-1)" "unprognostic (3.52e-1)" "unprognostic (3.20e-2)" "unprognostic (2.26e-2)" 6.0 19.1 2.9 11.2 3.3 2.0 5.1 3.6 5.4 4.6 3.7 5.1 7.8 5.5 0.0 10.6 4.4 1.7 7.5 3.3 3.5 4.8 4.2 4.6 5.5 3.2 3.2 3.6 4.3 3.7 3.7 7.5 3.5 2.9 3.1 6.4 7.1 2.2 11.6 4.8 4.8 2.4 3.9 5.6 4.4 3.3 3.1 6.8 4.3 3.6 6.8 5.1 6.0 4.0 16.1 8.0 33.1 8.3 12.5 7.5 16.3 28.6 7.0 12.6 9.0 13.5 16.7 14.1 22.2 10.4 24.0 16.7 20.9 4.6 17.0 23.3 4.3 19.4 11.7 8.0 12.2 18.4 24.3 8.0 8.3 15.6 8.8 13.6 7.1 13.0 12.5 8.7 12.2 16.4 21.3 13.2 18.8 16.5 12.4 15.6 12.4 16.5 15.1 28.4 14.4 10.7 13.0 18.9 24.4 27.1 14.5 29.2 14.3 15.9 18.0 19.7 24.4 12.1 24.8 24.3 22.4 8.9 23.7 34.1 13.6 15.6 14.2 16.3 13.9 15.8 16.3 15.8 16.7 12.7 15.6 17.3 17.7 19.6 15.4 11.8 21.9 16.2 2.9 3.3 3.6 5.4 3.3 3.5 3.2 3.2 3.5 3.9 3.1 4.0 0.0 9.6 2.6 1.6 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 MOB4 "2C4D, CGI-95, DKFZP564M112, MOB3, MOBKL3, PHOCN, PREI3" ENSG00000115540 "MOB family member 4, phocein" Q9Y3A3 2 197515571-197553699 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 367.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB034082, HPA044125" Approved NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB034082: AB_1127220, HPA044125: AB_2678822" "unprognostic (4.60e-2)" "unprognostic (3.23e-1)" "unprognostic (2.16e-2)" "unprognostic (2.81e-2)" "unprognostic (2.53e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.23e-1)" "unprognostic (4.88e-2)" "unprognostic (1.72e-1)" "unprognostic (8.03e-2)" "unprognostic (8.44e-2)" "prognostic unfavorable (4.68e-4)" "unprognostic (3.35e-1)" "unprognostic (8.36e-2)" "unprognostic (3.30e-2)" "unprognostic (3.07e-2)" 22.1 88.5 16.4 18.1 17.1 64.8 28.5 20.6 25.2 23.1 13.0 25.0 18.4 27.5 23.8 42.9 18.8 22.1 41.1 17.5 18.2 21.9 21.5 20.1 23.7 15.4 16.7 23.6 17.8 28.7 11.9 32.3 16.2 28.2 26.5 13.9 19.4 22.2 36.1 21.1 20.6 32.4 17.9 19.1 19.0 10.9 17.5 23.8 24.6 36.9 28.7 31.0 19.4 19.0 51.6 27.1 68.2 26.1 54.3 51.3 63.9 57.3 57.1 77.5 64.2 64.8 39.5 46.5 52.4 65.2 54.6 30.2 56.0 57.5 92.2 36.8 41.1 61.4 46.8 62.6 49.5 50.6 50.2 51.1 40.1 52.8 37.7 49.3 53.6 34.5 33.3 28.1 75.0 57.0 31.6 84.2 62.7 51.5 63.8 32.6 55.4 36.2 72.8 84.5 33.3 46.0 42.0 58.5 54.9 89.2 38.6 55.0 46.1 54.6 27.5 58.3 60.6 30.0 43.9 58.7 44.8 35.2 56.6 24.8 9.2 18.2 9.7 11.7 12.1 12.8 10.9 13.0 11.4 10.9 12.9 14.0 22.8 14.7 12.3 10.5 16.9 10.8 16.4 17.1 20.6 25.2 17.5 18.2 15.4 16.7 16.2 17.9 17.5 19.0 53.6 28.9 26.1 0.0 70.5 77.5 50.8 107.0 56.9 39.8 38.3 36.4 54.3 32.9 60.2 20.2 10.4 145.8 77.9 45.3 88.0 64.3 1.7 23.3 28.2 54.1 34.0 31.5 0.0 50.4 101.6 49.5 32.6 23.4 41.3 18.8 40.0 25.9 57.8 47.1 0.0 48.3 97.6 33.7 98.6 4.6 42.6 42.3 58.7 0.0 50.8 56.2 54.6 0.0 0.0 66.4 35.7 38.4 61.7 54.4 34.2 66.7 44.4 32.5 52.6 39.3 74.8 54.3 43.3 54.7 83.5 367.4 82.9 58.5 36.6 65.7 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 MARS2 "mtMetRS, SPAX3" ENSG00000247626 "Methionyl-tRNA synthetase 2, mitochondrial" Q96GW9 2 197705369-197708395 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.1;Suprabasal keratinocytes: 18.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035589, HPA035590" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" "HPA035589: AB_10601870, HPA035590: AB_2674693" "unprognostic (2.12e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.12e-4)" "unprognostic (2.99e-2)" "unprognostic (2.35e-2)" "unprognostic (1.53e-1)" "unprognostic (7.61e-2)" "unprognostic (1.04e-1)" "unprognostic (9.54e-2)" "unprognostic (1.86e-3)" "prognostic favorable (6.14e-5)" "unprognostic (1.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-2)" "unprognostic (8.74e-2)" 3.0 4.7 1.8 4.7 2.9 3.6 4.1 3.0 3.0 1.8 1.4 5.4 4.7 1.9 1.4 4.9 2.3 2.2 4.1 2.1 2.5 4.0 5.7 2.0 6.5 2.7 2.7 1.6 5.3 4.1 0.9 2.5 3.2 2.0 5.0 1.7 3.1 1.7 4.8 3.2 3.7 2.5 2.5 4.5 3.3 1.9 2.7 3.2 3.1 6.0 6.6 4.2 2.2 4.1 6.9 8.2 7.7 13.0 7.2 3.5 14.5 5.2 4.1 9.8 7.3 21.1 6.3 43.4 7.6 3.0 5.2 12.8 27.2 11.2 10.3 11.8 15.9 26.7 9.7 18.7 6.8 39.7 12.3 3.7 14.0 6.6 11.3 2.6 6.5 12.6 31.7 15.1 5.6 11.7 20.3 18.7 13.3 16.1 20.6 20.7 8.1 30.7 11.8 12.2 13.6 6.5 6.5 17.5 11.9 10.0 7.5 13.8 5.2 8.0 6.3 6.1 15.4 10.0 8.0 35.7 6.0 23.8 7.5 0.0 2.5 0.7 4.3 4.0 5.0 2.7 3.5 3.9 4.0 3.0 5.6 6.3 0.1 8.6 1.9 2.8 6.6 3.6 1.8 2.9 3.0 3.0 2.1 2.5 2.7 2.7 3.2 2.5 2.7 4.1 0.7 0.0 1.1 0.7 5.3 17.1 6.2 2.6 9.1 1.7 3.3 1.4 1.9 0.0 1.8 3.7 0.0 1.8 2.1 3.7 5.9 2.1 2.8 0.6 1.7 2.2 0.0 7.2 1.7 1.8 1.3 1.6 3.1 0.9 4.5 1.5 1.1 7.7 2.6 0.0 1.7 1.6 0.0 2.2 4.2 0.8 1.5 0.8 5.4 2.8 1.7 1.6 0.0 1.5 2.0 1.2 2.4 0.4 2.1 3.1 1.1 4.4 1.3 2.3 0.0 2.5 3.1 3.5 2.7 7.3 18.9 0.8 3.9 4.1 5.4 4.8 BOLL BOULE ENSG00000152430 "Boule homolog, RNA binding protein" Q8N9W6 2 197726879-197786762 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 48.9" "Cell type enhanced" "Detected in some" "Early spermatids: 178.2;Late spermatids: 129.3;Spermatocytes: 327.7;Spermatogonia: 63.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "T-reg: 1.5" "Lineage enriched" "Detected in single" 9 "T-cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA018678, HPA048813" Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA018678: AB_1845411, HPA048813: AB_2680529" "unprognostic (3.55e-2)" "unprognostic (1.69e-1)" "unprognostic (6.05e-2)" "unprognostic (3.08e-2)" "unprognostic (7.93e-2)" "unprognostic (3.20e-1)" "unprognostic (3.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.80e-1)" "unprognostic (3.08e-1)" "unprognostic (9.49e-2)" "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 48.9 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 178.2 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 129.3 4.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 3.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.3 327.7 63.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 PLCL1 "PLC-L, PLCE, PLCL, PPP1R127, PRIP" ENSG00000115896 "Phospholipase C like 1 (inactive)" Q15111 2 197804593-198572581 "Metabolic proteins, Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.3;tongue: 40.8" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 2062.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 6 "T-cells: 1.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.7;K-562: 15.6;Karpas-707: 10.7;MOLT-4: 11.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031849 Enhanced NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA031849: AB_10602192" "unprognostic (7.77e-3)" "unprognostic (2.57e-1)" "unprognostic (2.09e-1)" "unprognostic (5.18e-3)" "unprognostic (4.40e-2)" "unprognostic (7.14e-2)" "unprognostic (2.05e-1)" "unprognostic (4.42e-3)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-2)" "unprognostic (7.42e-2)" "prognostic favorable (3.91e-7)" "unprognostic (1.07e-4)" "unprognostic (6.74e-2)" "unprognostic (1.68e-1)" "unprognostic (3.20e-2)" 4.0 4.1 15.6 2.7 40.5 1.6 2.4 32.5 21.4 4.5 9.5 4.0 0.6 14.8 3.1 3.6 3.3 3.0 32.4 13.8 30.8 31.5 0.5 3.2 3.4 42.6 37.4 7.0 1.6 14.8 2.1 7.9 39.2 10.5 1.3 4.0 2.3 7.1 30.8 0.9 1.8 6.0 22.6 1.9 2.2 1.7 27.7 17.2 3.3 40.8 2.6 4.1 1.9 65.3 0.0 0.0 0.1 0.0 1.6 0.4 0.0 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 1.5 0.0 0.2 0.0 1.8 4.2 0.0 0.0 0.0 0.0 8.7 2.9 15.6 10.7 0.1 0.4 11.4 0.0 0.1 0.0 0.0 0.0 0.0 4.7 0.2 0.0 1.6 0.9 1.8 0.0 2.5 0.8 0.2 0.0 0.7 0.2 0.0 0.0 0.1 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 1.4 0.0 15.6 40.5 32.5 21.4 13.8 30.8 42.6 37.4 39.2 22.6 27.7 65.3 7.0 19.2 4.4 44.4 0.9 1.3 0.8 0.0 0.6 14.8 2.0 1.8 159.0 1.5 1.9 14.7 0.0 0.1 0.8 1.8 58.7 0.9 15.5 2.0 102.7 5.4 1.8 0.0 201.0 0.4 0.0 6.0 1.1 1.9 6.3 3.8 0.4 0.0 3.1 15.2 160.9 0.0 2.0 4.1 2.0 3.8 1.8 4.6 0.0 49.6 2.9 2.7 0.0 181.5 2062.6 0.2 0.0 7.9 3.8 0.6 0.6 52.4 2.2 1.2 32.9 5.4 31.8 1.0 1.8 0.2 1.3 0.1 8.2 1.6 0.1 0.3 SATB2 "FLJ21474, KIAA1034" ENSG00000119042 "SATB homeobox 2" Q9UPW6 2 199269500-199471266 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 13.9;intestine: 39.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 129.7;Enteroendocrine cells: 99.7;Excitatory neurons: 363.9;Intestinal goblet cells: 66.9;Paneth cells: 70.0;Undifferentiated cells: 84.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.0" "Group enriched" "Detected in many" 84 "basal ganglia: 10.9;cerebral cortex: 13.9;hippocampal formation: 4.6;white matter: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 40.3;K-562: 45.1;THP-1: 59.8" "Region enhanced" "Detected in many" "cerebral cortex: 29.2" "Group enriched" "Detected in all" 5 "cerebral cortex: 46.4;hippocampal formation: 37.1" "HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231" Enhanced Supported Nucleoplasm NA NA "Cluster 37: Intestine - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "CAB023669: AB_1129287, CAB062562: AB_2665615, CAB067751: AB_2665629, CAB068229: AB_2665628, CAB068230: AB_2665630, CAB068231: AB_2665631, HPA001042: AB_10601711, HPA029543: AB_10959737" "unprognostic (1.77e-2)" "unprognostic (1.90e-1)" "unprognostic (8.53e-3)" "unprognostic (4.77e-2)" "unprognostic (1.07e-1)" "unprognostic (9.39e-3)" "unprognostic (1.80e-1)" "unprognostic (5.54e-3)" "unprognostic (8.26e-2)" "unprognostic (3.75e-1)" "unprognostic (2.04e-2)" "unprognostic (1.13e-1)" "prognostic favorable (5.37e-8)" "unprognostic (1.14e-1)" "unprognostic (2.84e-1)" "unprognostic (7.95e-6)" "unprognostic (1.08e-3)" 2.7 4.8 0.0 4.3 10.9 0.3 2.2 0.0 13.9 2.7 0.0 34.2 1.5 1.7 0.9 0.8 1.4 1.3 0.7 4.6 0.0 4.0 3.0 0.9 0.5 0.0 0.0 1.9 3.9 2.1 1.0 0.6 0.0 1.9 39.5 0.8 1.5 2.8 2.2 1.8 5.7 3.0 0.0 0.7 1.0 2.8 0.0 0.2 1.6 2.7 1.0 1.6 3.1 3.9 2.6 1.7 17.6 8.1 8.3 9.9 1.3 6.2 8.9 4.4 5.7 0.4 5.8 0.9 0.2 13.3 6.9 0.5 14.0 3.7 7.0 9.4 12.3 40.3 4.1 4.9 1.9 18.7 17.1 4.8 6.4 8.8 5.6 11.3 0.4 6.0 45.1 0.0 12.8 0.9 0.8 22.9 3.2 2.0 2.9 1.7 6.0 0.1 6.6 0.6 3.8 0.0 3.1 0.0 9.5 3.1 3.6 59.8 6.2 31.5 5.9 10.1 16.6 2.6 8.9 25.9 21.7 14.6 25.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 13.9 4.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 1.4 0.0 1.1 18.6 0.6 1.8 2.7 0.5 0.6 2.4 0.9 0.4 1.5 0.0 0.7 0.0 4.2 0.1 0.2 129.7 1.9 0.3 1.0 0.9 3.9 1.5 99.7 0.0 363.9 2.7 0.3 3.6 0.0 0.7 0.0 1.6 1.8 5.4 0.8 0.0 3.5 66.9 0.0 2.5 3.0 0.9 2.5 1.0 5.4 9.4 0.6 0.5 0.0 21.1 34.1 1.2 70.0 1.2 0.0 4.3 19.1 7.6 0.2 0.5 0.0 1.7 10.4 6.1 4.1 0.8 3.0 0.1 1.3 3.9 84.7 2.2 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 C2orf69 FLJ38973 ENSG00000178074 "Chromosome 2 open reading frame 69" Q8N8R5 2 199911293-199955935 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 132.1;Spermatocytes: 124.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045225 Approved "Secreted to blood" NA Yes "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045225: AB_10960841" "unprognostic (6.94e-3)" "unprognostic (1.09e-1)" "unprognostic (7.17e-2)" "unprognostic (3.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.95e-1)" "unprognostic (4.39e-3)" "unprognostic (1.92e-2)" "unprognostic (5.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.33e-3)" "unprognostic (1.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.41e-3)" "unprognostic (8.87e-2)" "unprognostic (1.03e-2)" "unprognostic (5.86e-2)" 9.7 14.1 8.5 6.8 8.7 22.1 7.4 7.7 12.4 5.7 6.3 8.0 8.4 6.4 6.5 6.8 3.8 6.2 6.7 9.6 9.2 8.9 10.0 6.0 7.3 7.7 8.3 4.8 8.2 9.2 4.1 5.3 7.8 6.5 8.0 10.4 6.2 4.7 9.1 6.4 7.4 7.6 8.4 7.0 7.1 14.7 9.3 5.2 6.7 9.8 7.4 6.8 4.0 10.0 16.1 7.2 13.2 18.0 18.2 22.8 22.3 22.6 13.5 15.0 17.7 16.3 11.4 13.2 12.9 16.0 15.9 12.8 14.1 12.0 25.1 19.8 12.8 20.4 12.4 20.8 10.6 20.7 24.2 11.8 10.5 17.2 14.9 8.1 17.0 8.8 14.9 25.5 25.6 13.9 11.6 18.1 19.4 7.1 19.1 11.0 17.2 11.9 14.8 16.4 21.5 9.4 10.9 8.1 17.4 16.9 12.0 17.7 14.9 23.3 19.0 26.2 18.2 16.7 29.0 13.0 18.6 13.1 12.0 5.4 2.7 7.2 3.6 3.5 5.2 3.1 4.0 3.4 2.4 3.0 4.2 4.5 2.3 2.0 2.7 1.3 4.1 2.8 8.5 8.7 7.7 12.4 9.6 9.2 7.7 8.3 7.8 8.4 9.3 10.0 13.5 3.2 5.1 12.4 22.9 38.0 29.8 8.8 9.1 21.8 10.1 3.7 11.4 12.8 7.6 16.5 29.2 13.3 11.0 16.4 27.4 12.8 132.1 7.9 10.2 16.1 18.6 27.8 19.4 18.3 18.0 17.0 13.7 7.1 8.2 14.8 23.6 19.7 11.8 13.5 13.9 16.9 10.2 18.0 32.1 78.1 13.4 13.4 16.0 12.2 14.0 56.5 12.3 12.5 27.0 14.6 9.3 21.8 8.6 24.6 18.1 20.4 11.8 26.5 19.7 14.0 14.9 124.3 44.1 15.7 44.9 9.9 18.1 11.1 17.5 19.5 TYW5 "C2orf60, FLJ37953" ENSG00000162971 "TRNA-yW synthesizing protein 5" A2RUC4 2 199928913-199955736 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028294, HPA045803" Uncertain Approved "Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA028294: AB_2672549, HPA045803: AB_10964878" "unprognostic (3.44e-3)" "unprognostic (3.74e-1)" "unprognostic (2.11e-1)" "unprognostic (3.03e-2)" "unprognostic (9.22e-3)" "unprognostic (4.95e-2)" "unprognostic (1.47e-3)" "unprognostic (9.72e-2)" "unprognostic (6.55e-3)" "unprognostic (6.30e-3)" "unprognostic (9.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.87e-3)" "unprognostic (8.67e-2)" "unprognostic (4.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.42e-3)" 1.0 2.1 2.7 1.4 2.9 3.6 2.1 4.4 3.9 1.0 2.7 1.3 1.8 1.5 1.9 0.9 1.2 1.0 0.9 2.9 2.6 1.6 2.5 1.4 2.3 2.5 2.5 1.7 1.0 1.6 0.5 1.1 2.6 1.4 1.5 7.0 1.7 1.1 1.8 3.7 2.1 1.1 2.2 2.5 1.6 1.1 2.7 1.2 1.7 0.9 1.5 1.0 0.5 4.0 1.3 1.6 2.0 1.7 1.5 1.8 2.3 1.9 1.2 1.5 1.3 1.8 1.6 1.1 1.2 1.3 1.7 1.7 3.1 1.5 2.2 2.0 1.3 2.1 2.7 2.3 3.6 2.4 1.5 1.9 3.5 0.9 3.1 3.5 1.3 1.5 1.7 1.4 0.9 1.9 1.7 3.9 2.4 1.5 2.6 1.5 1.7 1.3 2.8 1.7 1.7 1.3 1.4 2.8 4.2 3.7 1.4 2.7 1.5 1.4 1.2 1.6 1.5 2.4 2.2 1.0 2.3 2.2 1.6 0.5 0.3 0.6 0.3 0.3 0.3 0.3 0.4 0.4 0.2 0.4 0.5 0.4 0.3 0.3 0.3 0.2 0.4 0.1 2.7 2.9 4.4 3.9 2.9 2.6 2.5 2.5 2.6 2.2 2.7 4.0 6.4 6.4 15.5 17.6 8.4 8.3 14.7 9.7 3.4 24.4 4.5 3.7 5.6 4.3 9.6 12.9 123.0 10.4 8.2 6.0 3.9 8.5 2.6 5.4 5.7 7.8 2.4 7.8 17.7 6.2 9.3 8.7 6.6 5.2 6.3 17.1 10.0 8.9 6.0 8.4 15.8 6.7 12.2 8.5 13.9 1.1 6.2 5.7 7.2 14.0 12.1 39.0 14.4 13.0 27.0 10.0 6.7 5.7 5.5 16.5 20.1 10.6 8.5 33.7 6.6 9.7 10.5 10.5 12.4 5.2 6.0 8.3 9.4 12.3 10.3 17.0 MAIP1 "C2orf47, DKFZp666A212, FLJ22555" ENSG00000162972 "Matrix AAA peptidase interacting protein 1" Q8WWC4 2 199955317-200008540 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.0;Distal tubular cells: 37.2;Ductal cells: 31.4;Exocrine glandular cells: 28.0;Extravillous trophoblasts: 33.8;Proximal tubular cells: 84.2;Syncytiotrophoblasts: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064013, HPA072231" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA064013: AB_2685175, HPA072231: AB_2732196" "unprognostic (4.89e-2)" "unprognostic (7.36e-2)" "unprognostic (7.40e-3)" "prognostic unfavorable (2.14e-4)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.81e-4)" "unprognostic (4.86e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (7.03e-2)" "unprognostic (2.00e-2)" "unprognostic (5.21e-3)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (1.63e-1)" "unprognostic (2.70e-2)" 11.1 16.1 7.0 8.3 7.2 18.7 11.3 10.1 8.4 7.3 6.5 14.4 21.1 7.8 7.4 11.7 9.0 8.1 16.6 7.5 6.5 31.1 46.2 7.4 8.8 6.7 6.5 7.5 10.3 12.2 5.8 9.3 7.3 9.1 13.1 7.2 9.6 9.0 22.2 9.7 16.8 7.5 7.1 8.5 12.6 4.9 6.8 9.3 9.7 16.8 10.4 9.2 8.2 8.6 23.9 21.8 19.3 15.2 16.8 16.9 44.5 21.1 20.2 30.7 29.3 59.5 21.0 15.7 29.6 14.6 25.4 25.8 28.7 22.7 28.8 24.7 32.9 26.4 18.5 54.7 22.6 36.7 18.0 18.1 18.3 20.3 21.9 17.6 19.7 29.9 35.2 19.8 20.2 31.4 27.8 34.0 24.7 25.2 51.6 26.4 22.9 31.6 36.6 30.5 21.8 15.1 21.7 24.4 40.1 24.3 21.6 22.1 17.6 17.9 25.6 15.6 23.7 18.8 23.6 33.7 27.0 21.1 18.7 9.9 12.9 9.4 10.8 12.8 13.3 13.8 10.6 7.7 16.8 14.1 10.0 8.6 2.0 8.9 12.6 13.5 13.9 8.2 7.0 7.2 10.1 8.4 7.5 6.5 6.7 6.5 7.3 7.1 6.8 8.6 11.7 9.6 14.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.8 14.1 0.0 0.0 5.0 3.7 0.0 30.0 7.0 0.0 37.2 31.4 0.0 10.0 10.2 6.1 0.0 0.0 0.0 28.0 33.8 6.2 0.0 11.9 3.8 12.2 0.0 0.0 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 21.2 0.0 0.0 1.3 0.0 0.0 84.2 5.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 32.0 4.0 18.3 0.0 0.0 SPATS2L "DNAPTP6, SGNP" ENSG00000196141 "Spermatogenesis associated serine rich 2 like" Q9NUQ6 2 200305881-200482264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 478.4;Paneth cells: 467.4;Proximal tubular cells: 568.2;Skeletal myocytes: 470.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 48.0" "Group enriched" "Detected in all" 5 "dendritic cells: 16.8;granulocytes: 48.0;T-cells: 31.6" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 475.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055427, HPA066310" Uncertain Enhanced Nucleoli,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "HPA055427: AB_2682813, HPA066310: AB_2685655" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (9.35e-2)" "unprognostic (1.78e-2)" "unprognostic (4.39e-3)" "unprognostic (3.58e-2)" "unprognostic (2.17e-3)" "unprognostic (3.44e-2)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (3.95e-1)" "unprognostic (7.84e-3)" "unprognostic (3.71e-2)" "unprognostic (5.67e-2)" "unprognostic (6.01e-2)" "unprognostic (2.99e-1)" 47.1 27.0 36.9 37.2 38.4 10.4 31.7 35.2 48.6 77.5 44.2 85.5 82.1 37.5 26.6 65.3 81.6 114.8 117.3 41.4 41.0 70.0 110.3 47.6 24.1 42.1 45.0 66.0 60.6 41.9 40.4 68.8 44.0 50.7 83.2 16.5 166.1 67.8 70.6 33.6 82.8 51.3 43.6 39.1 101.4 28.9 39.9 40.8 42.9 36.3 22.9 81.2 45.7 46.7 174.8 94.6 113.0 13.8 74.0 96.4 43.4 299.6 100.1 193.2 143.8 262.6 190.0 1.0 69.1 197.4 108.5 167.5 35.2 186.9 130.4 109.5 47.2 1.4 80.0 315.2 138.8 28.9 12.3 121.4 182.5 134.3 128.3 138.0 75.4 21.6 41.1 119.0 280.0 55.4 4.4 8.3 28.2 303.4 226.7 0.6 388.2 11.1 475.5 134.2 3.1 31.9 77.0 45.5 127.0 165.3 23.9 39.5 120.9 131.3 129.3 41.4 170.9 34.9 36.3 2.2 104.1 14.1 179.5 48.0 5.2 7.6 5.8 5.9 14.0 2.8 6.3 6.0 16.8 3.3 2.6 3.1 4.2 6.8 4.7 12.8 31.6 2.8 36.9 38.4 35.2 48.6 41.4 41.0 42.1 45.0 44.0 43.6 39.9 46.7 83.4 86.6 26.2 104.5 11.2 91.1 262.5 123.6 67.7 21.4 63.2 51.4 127.8 403.2 70.3 172.9 12.5 19.4 9.5 478.4 111.6 157.7 75.9 129.8 59.4 64.2 55.1 15.1 116.4 147.0 38.2 101.8 151.9 56.9 56.5 51.4 94.2 230.0 82.5 60.6 202.9 246.6 54.9 139.6 98.1 22.4 165.6 56.1 128.1 68.4 18.0 8.7 2.1 79.9 106.5 210.8 467.4 142.1 9.4 284.9 153.2 568.2 167.1 56.4 78.9 470.9 89.3 38.0 82.6 68.4 77.9 9.9 28.2 6.6 78.4 198.8 KCTD18 "6530404F10Rik, FLJ31322, FLJ37818" ENSG00000155729 "Potassium channel tetramerization domain containing 18" Q6PI47 2 200488958-200519784 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045498, HPA058028" Approved Approved Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Mitochondria "HPA045498: AB_10959387, HPA058028: AB_2683583" "unprognostic (2.90e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (2.55e-1)" "unprognostic (4.01e-1)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.16e-1)" "unprognostic (2.76e-2)" "unprognostic (2.40e-2)" "unprognostic (1.18e-2)" "unprognostic (5.21e-1)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (6.58e-2)" "unprognostic (1.05e-2)" "unprognostic (1.31e-1)" 9.9 8.9 8.2 7.6 9.6 9.8 10.2 8.9 9.9 8.4 9.0 10.1 8.7 8.5 8.2 9.0 8.8 7.2 8.4 7.8 8.5 9.9 10.0 8.5 11.0 9.1 9.1 10.4 11.9 10.4 6.3 6.2 9.3 11.1 8.4 5.6 10.6 9.4 10.6 9.2 7.9 7.7 9.0 10.2 9.3 7.2 8.7 10.6 13.8 8.9 11.0 9.8 8.0 9.4 10.2 9.3 4.5 16.9 21.2 26.2 11.6 12.3 15.4 7.7 10.1 7.5 11.4 7.1 9.1 12.4 12.6 9.6 4.5 14.8 9.8 17.3 4.9 10.2 6.7 5.3 14.4 8.4 11.6 17.6 27.4 8.9 16.9 17.9 6.7 10.5 7.1 9.5 13.9 10.5 18.2 8.2 2.5 8.7 8.3 12.5 10.2 8.4 10.1 10.0 5.1 7.1 9.7 8.2 15.1 9.7 10.9 13.4 11.4 15.7 3.6 8.0 5.9 18.1 14.0 8.0 18.0 8.8 11.3 7.8 3.2 6.4 3.2 4.7 4.9 4.0 4.1 4.8 3.4 4.0 5.1 5.1 2.5 4.6 3.2 4.1 5.0 3.2 8.2 9.6 8.9 9.9 7.8 8.5 9.1 9.1 9.3 9.0 8.7 9.4 7.8 6.4 9.4 7.2 11.3 4.5 5.9 5.7 10.8 7.2 9.1 6.9 6.2 8.6 6.5 3.7 0.0 8.0 10.8 5.6 1.9 7.2 22.7 8.8 7.3 5.7 1.2 3.4 10.1 8.4 7.8 8.6 8.2 5.3 2.5 11.8 8.6 9.4 7.2 10.1 9.5 8.4 6.1 11.4 6.6 4.2 11.8 11.2 7.2 6.5 16.7 11.1 18.6 6.6 18.3 6.5 7.4 12.4 7.5 5.8 8.5 13.5 9.8 10.5 19.7 12.2 7.9 19.0 16.5 12.8 4.0 5.1 10.1 11.0 7.3 4.0 SGO2 "FLJ25211, SGOL2, TRIPIN" ENSG00000163535 "Shugoshin 2" Q562F6 2 200510008-200584096 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.9;testis: 32.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.6;Endometrial ciliated cells: 12.1;Extravillous trophoblasts: 31.0;granulocytes: 11.4;Granulosa cells: 23.4;Hofbauer cells: 13.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "basophil: 16.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035163, HPA040817" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA035163: AB_10602397, HPA040817: AB_2677149" "unprognostic (3.43e-1)" "unprognostic (1.70e-1)" "unprognostic (7.06e-3)" "unprognostic (6.71e-3)" "unprognostic (1.90e-1)" "unprognostic (1.77e-1)" "unprognostic (7.55e-6)" "unprognostic (1.12e-2)" "unprognostic (1.98e-3)" "unprognostic (4.87e-2)" "unprognostic (1.37e-4)" "unprognostic (9.49e-2)" "unprognostic (8.07e-9)" "unprognostic (5.21e-2)" "unprognostic (5.43e-2)" "unprognostic (9.86e-2)" "unprognostic (2.02e-1)" 3.3 0.9 0.6 4.4 0.9 6.8 1.9 0.8 0.9 0.9 0.3 3.1 2.5 1.8 0.7 2.4 1.4 1.2 1.0 0.5 0.9 0.9 0.8 1.5 7.9 0.9 0.9 1.9 0.5 1.1 0.3 2.6 0.9 1.4 3.2 0.9 0.7 0.7 0.4 2.3 2.6 2.0 0.7 2.0 1.8 32.6 0.9 14.9 1.2 0.6 8.1 1.5 0.9 1.2 34.6 16.2 37.0 17.4 5.2 7.9 23.7 38.7 16.6 32.0 33.1 24.3 23.5 22.5 18.6 18.1 34.4 25.3 33.6 20.1 54.5 48.0 16.9 43.5 21.6 17.5 1.6 43.9 33.1 3.4 2.5 32.9 17.3 8.0 29.4 31.3 33.1 31.6 61.4 15.4 35.9 17.9 26.7 24.9 41.2 28.8 49.1 21.3 13.3 13.6 22.2 15.4 28.6 13.3 16.3 29.2 14.1 25.2 18.1 33.9 34.0 31.6 34.0 14.3 33.5 49.8 21.4 28.9 49.4 16.7 1.4 4.5 2.2 1.4 1.4 2.7 2.4 2.2 0.8 3.2 1.8 2.2 1.0 2.0 1.7 1.7 3.6 1.2 0.6 0.9 0.8 0.9 0.5 0.9 0.9 0.9 0.9 0.7 0.9 1.2 9.4 3.2 3.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 5.8 7.1 0.0 0.0 6.2 0.0 0.0 11.6 7.8 0.0 3.9 3.9 0.0 12.1 5.3 3.3 0.0 0.0 0.0 2.7 31.0 6.7 0.0 3.6 11.4 23.4 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.2 0.0 0.0 1.7 0.0 0.0 2.5 8.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 3.4 3.8 4.0 0.0 0.0 AOX1 "AO, AOH1" ENSG00000138356 "Aldehyde oxidase 1" Q06278 2 200586014-200677064 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 300.5;liver: 891.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 749.1" "Cancer enriched" "Detected in many" 9 "liver cancer: 122.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 377.3;ASC TERT1: 191.5;HSkMC: 78.2;hTERT-HME1: 81.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040199, HPA040215" Enhanced NA NA 3300000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "HPA040199: AB_10795273, HPA040215: AB_10795360" "unprognostic (4.39e-2)" "unprognostic (1.03e-3)" "unprognostic (1.96e-1)" "unprognostic (3.15e-2)" "unprognostic (1.17e-4)" "unprognostic (1.92e-2)" "unprognostic (2.34e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (4.93e-2)" "unprognostic (5.48e-2)" "unprognostic (2.00e-2)" "prognostic favorable (6.05e-5)" "unprognostic (1.33e-2)" "unprognostic (8.16e-3)" "unprognostic (3.38e-2)" "unprognostic (4.99e-3)" 87.6 300.5 0.6 3.2 2.9 0.5 50.2 0.1 2.4 17.9 3.6 12.0 0.8 10.8 12.3 8.2 48.2 9.9 14.9 1.1 1.5 103.2 891.0 19.5 4.7 1.3 1.0 48.0 85.0 1.3 2.8 1.7 1.2 22.3 4.5 0.5 15.3 28.3 12.9 20.1 12.7 7.1 0.5 4.1 14.3 19.4 4.0 2.0 17.7 11.0 1.5 38.6 17.7 3.6 0.6 0.2 0.0 0.0 377.3 191.5 0.2 6.6 12.2 5.4 9.7 0.0 0.1 0.1 0.5 8.4 2.3 0.2 0.1 18.6 22.0 0.2 0.6 0.0 4.6 20.7 25.4 0.9 0.0 78.2 4.6 26.1 81.2 5.4 0.2 0.2 0.2 0.1 18.3 0.5 0.0 0.1 8.0 0.1 5.2 0.0 0.5 0.1 0.2 0.2 0.4 0.3 4.8 0.0 0.3 0.4 0.1 0.2 31.9 13.8 11.2 0.2 2.5 0.2 0.1 2.6 10.7 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.1 2.4 1.1 1.5 1.3 1.0 1.2 0.5 4.0 3.6 1.0 3.2 1.1 0.7 3.6 1.8 0.5 1.2 1.2 0.1 0.2 0.3 0.9 17.2 0.1 3.7 0.0 0.1 0.0 0.1 11.7 0.7 0.8 0.4 3.0 2.6 3.0 37.5 0.9 26.2 0.2 22.9 0.0 8.2 0.0 0.1 15.4 749.1 0.4 0.0 2.5 0.1 2.0 19.8 3.6 4.4 74.0 1.7 3.6 1.0 0.0 0.6 0.0 5.0 6.9 11.5 0.0 82.0 0.0 7.5 0.1 162.2 0.1 0.1 0.0 5.3 3.0 0.8 1.3 0.1 1.6 0.0 2.0 2.3 0.1 0.4 BZW1 "BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 3845.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" 130.6 129.1 30.3 97.5 33.0 219.6 88.7 37.7 40.9 65.5 49.2 98.4 64.6 66.6 58.4 120.8 53.4 93.1 56.4 33.9 36.9 88.5 227.0 73.5 97.9 36.5 36.7 62.3 62.6 72.4 30.7 105.2 35.3 99.6 90.6 45.8 61.2 61.7 101.7 47.9 71.4 80.1 39.1 62.8 69.0 170.9 42.1 123.0 74.4 75.2 109.4 164.6 61.4 45.4 296.6 230.1 309.4 187.1 305.2 353.3 221.6 425.2 501.8 281.2 244.5 360.7 195.3 142.5 144.7 339.7 186.1 159.8 284.9 512.6 521.8 154.6 151.3 370.8 453.9 280.1 244.5 420.9 199.6 205.3 233.5 373.2 398.9 244.6 495.4 132.3 328.5 234.0 379.3 236.6 387.9 201.3 392.4 120.1 575.4 293.1 333.4 148.6 256.1 435.2 188.9 218.7 325.5 120.9 226.1 255.5 126.6 216.7 555.0 416.8 242.9 255.2 276.6 286.1 428.6 377.8 341.2 209.3 312.1 236.7 140.7 168.5 177.9 173.4 207.2 102.0 126.0 167.5 162.6 87.1 112.4 156.7 117.0 218.5 195.1 75.5 171.5 294.6 30.3 33.0 37.7 40.9 33.9 36.9 36.5 36.7 35.3 39.1 42.1 45.4 207.3 86.6 108.1 31.3 148.5 198.5 318.5 310.7 125.7 37.1 159.0 89.8 18.1 82.9 290.3 90.1 18.8 115.4 263.2 127.5 138.9 250.2 927.0 108.3 145.3 149.0 96.7 72.8 28.7 233.1 164.3 181.2 72.4 150.0 196.9 72.7 99.2 262.4 114.1 58.9 32.1 113.3 183.1 88.6 194.0 3845.6 102.2 169.1 124.5 15.0 308.1 119.6 170.0 24.6 36.6 464.4 106.5 95.9 132.7 242.3 68.2 163.3 121.7 33.4 98.6 159.4 179.8 175.2 169.2 133.2 196.1 195.2 200.3 103.3 106.1 370.9 CLK1 ENSG00000013441 "CDC like kinase 1" P49759 2 200853009-200864744 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033141, HPA062405" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear membrane" "CAB033141: AB_1121713, HPA062405: AB_2684753" "unprognostic (9.79e-2)" "unprognostic (2.05e-1)" "unprognostic (2.15e-2)" "unprognostic (1.63e-1)" "unprognostic (9.19e-2)" "unprognostic (4.50e-3)" "unprognostic (1.52e-1)" "unprognostic (2.77e-3)" "unprognostic (1.78e-2)" "unprognostic (2.09e-2)" "unprognostic (1.09e-2)" "unprognostic (5.63e-3)" "unprognostic (2.03e-3)" "unprognostic (9.66e-2)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "prognostic favorable (2.28e-4)" 89.6 82.7 132.9 25.4 137.1 178.0 72.2 140.9 201.6 118.5 136.2 78.3 20.8 65.8 51.1 58.5 85.5 56.5 83.9 133.9 137.7 83.3 84.4 90.3 55.9 138.1 133.4 140.3 63.6 29.0 82.3 64.8 138.6 109.7 24.2 133.8 68.9 49.6 80.4 62.5 51.6 30.9 135.2 113.0 53.2 28.1 134.1 76.0 92.5 71.4 42.0 77.8 112.8 176.0 17.9 13.5 22.6 6.5 24.4 26.1 17.1 19.2 26.8 19.3 25.5 24.6 11.8 5.5 13.1 11.4 11.1 19.7 27.9 8.8 38.2 27.3 24.0 18.1 35.9 30.7 14.7 19.5 31.1 12.3 39.9 23.4 41.8 20.6 11.4 9.5 23.3 77.1 27.0 12.3 23.0 58.4 13.9 11.4 29.8 24.8 25.7 31.8 13.0 11.2 22.0 17.8 16.4 6.1 32.7 12.9 5.3 13.2 19.5 21.4 14.8 21.5 22.0 46.8 20.9 13.7 14.2 15.4 14.9 40.0 7.2 18.6 14.5 5.0 17.3 17.4 15.7 15.8 4.8 11.7 15.6 12.9 16.9 9.5 6.0 11.1 17.2 10.4 132.9 137.1 140.9 201.6 133.9 137.7 138.1 133.4 138.6 135.2 134.1 176.0 122.1 44.8 85.4 112.0 164.2 168.8 263.0 73.6 114.4 59.0 112.9 97.0 96.6 41.5 87.1 27.6 100.1 46.7 213.5 110.9 19.6 31.4 2.3 111.2 108.8 113.6 134.3 87.5 51.7 26.9 56.6 142.5 81.1 173.6 136.9 77.9 82.1 43.3 58.5 52.2 53.6 124.2 50.8 100.5 285.8 9.4 92.9 192.3 154.7 62.8 56.2 54.6 76.2 58.3 169.0 32.0 117.7 75.6 169.0 133.3 88.2 14.9 70.1 99.6 111.7 97.8 128.4 33.1 27.7 117.0 151.7 90.3 261.2 43.0 88.6 184.2 PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Nucleoli "HPA040765: AB_2677125, HPA062187: AB_2684706" "unprognostic (8.96e-3)" "unprognostic (6.07e-2)" "unprognostic (5.34e-2)" "unprognostic (8.16e-2)" "unprognostic (2.69e-2)" "unprognostic (9.61e-2)" "unprognostic (8.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.40e-2)" "prognostic favorable (1.19e-4)" "unprognostic (5.23e-2)" "unprognostic (6.60e-2)" "prognostic unfavorable (5.16e-4)" "unprognostic (1.14e-1)" "unprognostic (5.96e-2)" "unprognostic (2.21e-2)" "unprognostic (4.87e-2)" 13.0 16.4 15.2 19.8 14.9 35.1 25.4 17.0 22.3 15.7 13.9 19.0 14.6 20.2 28.4 18.6 22.5 13.0 18.2 14.6 16.8 18.4 21.9 15.0 32.2 15.7 15.5 35.4 12.1 14.0 14.9 17.7 16.8 15.1 19.5 25.8 17.1 18.2 18.0 18.0 18.1 12.4 15.4 17.5 19.0 21.1 15.5 30.1 20.8 11.1 32.5 16.2 12.5 18.2 19.9 18.3 53.0 23.5 42.5 90.8 17.5 32.0 35.3 37.1 37.2 13.0 37.5 19.5 32.0 35.4 41.9 24.6 19.3 38.1 33.2 41.4 43.8 84.0 48.3 90.6 21.3 79.7 39.8 32.7 37.7 30.3 47.1 62.0 25.3 38.4 67.4 46.3 46.3 32.4 61.7 67.2 32.9 19.8 28.9 23.3 30.5 29.1 49.6 30.4 22.2 21.1 31.3 29.9 51.7 62.3 24.6 36.9 34.2 51.4 28.8 31.2 26.2 45.5 51.0 94.2 39.6 36.2 33.7 36.2 17.5 19.7 17.5 16.4 25.5 35.2 20.9 17.7 30.9 26.7 25.3 27.6 4.5 31.8 23.1 25.6 30.3 14.6 15.2 14.9 17.0 22.3 14.6 16.8 15.7 15.5 16.8 15.4 15.5 18.2 12.5 0.0 11.5 16.0 33.6 31.7 43.1 71.5 37.5 12.0 23.7 28.2 18.5 15.7 30.4 16.5 10.4 50.3 24.8 9.7 56.7 26.0 44.1 16.1 21.4 16.2 9.5 25.5 19.3 16.1 51.6 22.1 16.3 13.4 26.0 17.2 13.6 19.4 47.0 3.3 18.1 25.3 48.8 32.1 59.1 9.5 36.7 26.8 28.4 9.4 30.2 23.1 37.0 15.1 19.7 18.2 18.1 28.2 24.5 15.9 25.4 59.7 28.7 11.9 19.7 18.2 39.6 45.7 22.6 34.5 46.3 30.8 31.1 8.9 29.4 35.6 NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 9800000 "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA036335: AB_10696654, HPA036336: AB_2675068, HPA061466: AB_2684532" "unprognostic (6.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (9.52e-5)" "unprognostic (2.48e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.51e-6)" "unprognostic (1.94e-1)" "unprognostic (8.53e-3)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.65e-2)" "unprognostic (6.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-3)" "unprognostic (8.61e-2)" 13.2 19.2 14.1 15.2 15.8 11.0 24.3 15.7 23.8 17.7 13.7 21.8 16.5 15.9 26.3 16.7 22.5 13.2 21.5 14.9 14.8 24.3 22.9 15.6 26.5 15.3 13.8 21.4 15.5 27.0 9.7 19.1 16.2 17.2 28.0 32.7 19.8 19.8 23.5 21.6 15.7 19.1 15.6 18.1 20.1 18.5 14.1 26.5 19.4 30.6 32.4 17.1 12.7 17.5 39.5 42.1 66.9 41.3 29.8 37.1 45.9 42.6 45.4 88.6 71.3 66.1 44.7 31.8 40.2 36.5 64.1 42.7 96.8 56.0 94.6 42.4 90.8 47.4 73.6 70.9 27.0 56.8 31.3 31.7 52.3 58.6 55.8 39.9 29.9 65.6 70.2 31.4 52.7 51.4 69.9 71.1 79.1 44.7 73.5 41.1 37.1 61.6 46.8 40.6 42.3 49.5 36.6 36.8 51.9 94.4 36.5 50.5 15.6 42.2 39.8 38.3 39.0 28.4 58.3 68.4 41.4 45.6 41.6 70.1 23.0 30.7 27.8 34.9 29.1 31.4 31.8 35.3 28.8 23.7 35.4 29.1 7.8 33.6 31.1 29.8 32.0 24.2 14.1 15.8 15.7 23.8 14.9 14.8 15.3 13.8 16.2 15.6 14.1 17.5 6.0 0.0 7.0 2.6 11.7 3.7 7.7 43.1 12.5 90.5 6.9 9.3 13.9 10.0 26.5 5.5 14.6 34.3 8.0 7.5 15.6 20.3 16.2 10.2 9.3 7.0 1.8 23.2 6.2 18.2 35.6 9.8 9.7 7.8 9.5 12.7 6.8 9.3 17.2 18.5 5.7 10.5 26.4 7.3 2.2 6.5 16.1 9.5 5.4 5.6 17.2 18.8 8.2 2.5 5.7 13.2 9.2 19.2 23.9 6.3 10.1 21.3 24.9 27.4 6.6 7.2 14.5 30.9 24.4 12.9 8.2 22.6 10.0 11.1 11.4 6.2 ORC2 ORC2L ENSG00000115942 "Origin recognition complex subunit 2" Q13416 2 200908977-200963680 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 107.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003693, HPA073881" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB003693: AB_425574, HPA073881: AB_2686640" "unprognostic (3.04e-1)" "unprognostic (1.76e-1)" "unprognostic (2.89e-1)" "unprognostic (8.12e-3)" "unprognostic (3.40e-2)" "unprognostic (1.52e-2)" "unprognostic (2.37e-3)" "unprognostic (3.28e-1)" "prognostic unfavorable (8.42e-4)" "unprognostic (6.18e-2)" "unprognostic (4.56e-2)" "unprognostic (4.63e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (9.67e-2)" "unprognostic (3.74e-1)" "unprognostic (1.42e-1)" "unprognostic (5.31e-3)" 5.9 4.9 2.8 6.7 3.1 5.7 8.0 7.6 4.6 5.8 4.6 7.2 9.1 6.0 6.0 5.8 5.1 4.3 8.8 2.7 3.3 5.6 5.2 4.9 8.5 2.4 2.6 6.8 6.9 7.2 5.1 5.6 2.6 6.4 6.8 7.8 7.1 5.8 6.7 8.4 7.7 4.8 1.4 6.5 7.0 20.8 2.6 9.4 8.3 6.0 8.4 5.4 5.8 5.0 17.8 12.3 13.9 13.9 5.6 9.5 23.4 18.1 11.4 16.3 16.1 26.3 14.2 11.2 12.6 10.7 18.3 14.3 30.6 20.6 24.7 24.9 28.2 26.1 22.1 32.4 11.0 20.7 17.7 8.9 12.0 16.7 20.4 12.8 19.1 18.3 42.5 13.3 14.6 16.9 29.1 19.5 33.6 17.2 29.6 20.6 14.1 16.3 17.2 14.1 22.0 16.5 15.9 14.0 10.4 27.2 10.0 10.2 14.7 14.2 14.6 12.3 18.3 9.4 24.1 17.9 11.3 19.9 13.6 0.3 2.5 3.9 3.2 1.0 4.3 5.5 4.5 3.2 2.1 4.6 5.7 4.1 1.2 3.2 1.9 4.9 3.3 1.6 2.8 3.1 7.6 4.6 2.7 3.3 2.4 2.6 2.6 1.4 2.6 5.0 12.9 9.6 18.5 30.7 16.5 19.1 9.0 7.7 23.9 14.6 12.3 7.6 18.0 14.3 14.8 9.2 25.0 20.6 17.5 12.8 7.9 10.0 56.0 11.5 14.1 12.7 4.2 26.7 54.6 12.3 18.5 10.0 14.8 13.3 10.8 27.5 13.2 10.9 8.9 6.7 61.4 13.1 4.1 7.0 7.1 11.6 12.2 7.0 10.6 24.4 11.4 7.0 20.6 41.7 55.9 10.5 9.0 8.2 16.3 9.7 15.2 9.1 12.1 14.9 19.7 13.1 9.1 107.2 22.1 16.1 15.5 10.8 14.7 6.9 14.7 8.4 FAM126B "HYCC2, MGC39518" ENSG00000155744 "Family with sequence similarity 126 member B" Q8IXS8 2 200973718-201071671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 4 "neutrophil: 25.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.7" "Cell line enhanced" "Detected in all" "U-266/84: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036166, HPA036167, HPA067307" Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Cell Junctions" Nucleoplasm "HPA036166: AB_10696651, HPA036167: AB_2674982, HPA067307: AB_2685821" "unprognostic (7.47e-3)" "unprognostic (5.54e-2)" "unprognostic (2.52e-1)" "unprognostic (9.08e-2)" "unprognostic (8.96e-2)" "unprognostic (3.01e-3)" "unprognostic (1.11e-2)" "unprognostic (2.61e-3)" "unprognostic (1.34e-1)" "unprognostic (1.48e-2)" "unprognostic (1.79e-2)" "unprognostic (1.90e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" 7.8 4.5 4.7 6.3 5.2 17.4 4.8 15.9 8.1 4.0 2.3 7.2 6.8 3.9 4.0 8.2 3.2 4.3 3.4 6.5 3.1 7.8 7.4 5.4 5.9 3.3 3.2 3.8 4.9 4.9 3.8 5.0 3.3 3.7 6.4 10.4 4.3 2.7 3.0 7.1 6.6 3.9 0.6 6.8 7.5 4.5 5.2 5.9 6.9 3.6 6.1 3.8 4.4 6.1 5.4 2.8 3.9 4.2 4.0 5.3 8.2 5.0 3.0 4.0 3.7 7.2 6.2 4.9 4.8 5.1 3.7 6.5 8.1 3.1 6.0 7.1 4.9 14.3 7.6 6.7 3.3 17.6 11.9 2.3 3.9 5.5 3.3 3.1 3.9 5.2 13.4 17.6 4.1 3.3 10.5 11.4 2.8 3.5 4.7 6.1 5.9 4.6 3.7 5.9 7.7 3.8 5.3 6.0 4.7 5.1 4.2 7.7 7.9 7.5 5.3 3.7 4.6 13.1 58.8 10.5 4.3 6.7 5.4 2.6 1.8 6.3 3.8 2.4 4.0 2.6 3.2 3.0 1.6 2.7 3.1 3.7 25.7 3.1 2.7 1.1 2.4 1.9 4.7 5.2 15.9 8.1 6.5 3.1 3.3 3.2 3.3 0.6 5.2 6.1 21.5 28.9 23.9 45.1 29.3 52.6 10.7 17.0 23.3 52.9 16.3 9.4 17.2 27.1 20.4 20.2 164.7 16.6 38.3 59.1 17.6 10.6 9.1 12.7 16.4 22.7 37.1 23.1 113.4 10.5 10.1 15.9 24.5 16.2 24.7 19.9 35.3 21.0 12.0 26.9 98.3 23.4 22.4 33.9 51.6 6.6 31.7 21.1 30.2 45.0 41.5 20.3 73.2 57.8 64.6 21.3 31.1 25.6 34.0 13.2 47.3 16.4 23.1 42.7 19.7 14.8 15.9 32.8 22.9 31.6 74.2 17.4 35.6 15.3 22.0 19.6 NDUFB3 B12 ENSG00000119013 "NADH:ubiquinone oxidoreductase subunit B3" O43676 2 201071433-201085750 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 704.3;tongue: 727.7" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1711.2;Distal tubular cells: 1064.4;Proximal tubular cells: 780.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034596 Enhanced NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA034596: AB_10602712" "unprognostic (5.38e-2)" "unprognostic (2.90e-1)" "unprognostic (4.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (7.24e-4)" "unprognostic (1.41e-3)" "unprognostic (6.29e-2)" "unprognostic (8.81e-3)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-1)" "unprognostic (1.37e-2)" "unprognostic (9.40e-3)" "unprognostic (9.20e-2)" "unprognostic (1.94e-1)" "unprognostic (7.27e-2)" 119.4 114.4 151.2 88.9 152.7 79.7 105.5 165.7 227.5 69.9 161.9 185.7 136.7 46.4 132.2 98.4 66.1 66.3 389.3 151.5 165.1 247.1 195.3 63.5 103.7 158.2 155.4 46.2 54.7 219.3 57.8 78.0 158.1 77.1 174.6 140.8 100.8 75.8 704.3 52.0 127.9 73.8 157.2 61.6 115.5 83.1 158.2 143.4 96.0 727.7 128.8 95.4 53.7 160.6 180.1 148.9 227.5 122.0 226.3 207.0 183.1 224.8 160.1 171.9 200.3 347.2 211.3 144.4 249.8 211.4 261.9 154.5 209.6 287.7 269.4 294.5 460.6 349.0 363.8 394.8 141.2 500.9 170.5 180.1 223.6 203.3 119.2 211.3 250.3 259.2 311.1 240.3 313.1 234.4 313.8 459.8 129.9 392.4 536.7 215.6 200.4 388.0 380.6 278.7 209.5 150.1 176.0 153.2 258.2 353.2 150.7 373.0 227.3 144.8 179.7 150.9 222.8 174.5 435.3 452.6 246.0 284.4 172.6 205.2 135.4 159.4 116.1 205.3 129.2 148.8 132.7 135.7 177.3 117.3 115.2 140.9 267.3 141.6 213.3 211.8 183.1 109.6 151.2 152.7 165.7 227.5 151.5 165.1 158.2 155.4 158.1 157.2 158.2 160.6 95.3 80.1 57.7 18.9 100.9 78.1 100.0 433.7 66.6 52.9 101.7 128.1 1711.2 141.5 205.1 187.6 12.5 254.6 83.5 473.9 1064.4 247.0 218.1 191.6 93.9 101.9 146.4 113.8 13.2 201.7 208.9 103.4 118.7 135.2 78.0 61.0 86.7 260.5 288.2 32.0 14.7 299.0 248.2 121.6 107.1 59.9 95.4 126.8 168.9 10.3 292.9 184.6 116.4 7.5 19.9 177.3 411.0 101.5 135.2 72.5 496.3 780.3 229.2 92.0 92.1 82.3 125.4 270.0 89.7 169.2 91.9 157.6 89.7 113.9 322.1 132.9 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CASP10 "FLICE-2, MCH4" ENSG00000003400 "Caspase 10" Q92851 2 201182898-201229406 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.3;NK-cells: 44.3;Paneth cells: 44.5;Plasma cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.3" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 8.8 2.4 5.7 9.2 5.5 19.5 6.5 4.5 5.8 4.0 4.4 13.2 21.8 3.3 6.2 8.8 5.4 7.4 6.7 4.7 5.1 8.1 6.2 11.5 8.9 6.0 5.0 1.6 4.8 2.3 1.3 9.6 5.8 3.9 13.4 1.3 5.4 3.1 4.9 5.7 18.4 5.1 5.6 22.6 10.2 1.2 7.3 8.7 5.3 2.8 10.4 9.0 5.1 5.4 4.4 3.5 0.3 0.4 0.1 0.3 7.5 0.7 4.6 0.4 1.8 4.6 9.8 0.5 7.0 2.5 1.7 2.9 0.2 2.3 1.3 2.1 4.8 12.2 4.0 15.1 1.6 8.3 12.7 0.5 2.0 5.3 0.4 0.3 25.3 5.1 14.9 17.4 0.4 0.3 15.9 7.8 0.6 6.0 2.4 8.8 0.5 18.4 8.7 6.2 0.2 0.1 4.1 0.2 1.9 3.0 0.2 7.8 10.0 0.4 0.8 3.4 0.2 18.7 12.1 0.5 4.5 6.3 0.2 5.9 11.7 0.7 6.4 16.5 5.6 8.2 5.2 3.6 6.5 7.7 7.2 6.4 2.1 8.5 19.3 6.6 1.2 7.2 5.7 5.5 4.5 5.8 4.7 5.1 6.0 5.0 5.8 5.6 7.3 5.4 20.7 19.2 10.0 0.3 15.8 6.0 2.7 10.6 5.2 0.0 1.3 0.9 1.8 8.6 9.4 9.2 0.0 1.1 20.5 71.3 1.9 16.2 1.2 7.7 7.4 29.7 2.4 14.9 0.3 10.4 0.7 4.2 26.5 12.0 7.6 0.8 26.4 7.1 9.4 0.0 0.5 21.6 4.1 26.6 17.5 0.0 0.6 16.2 7.2 33.7 22.0 0.5 44.3 0.0 0.9 8.6 44.5 0.0 49.7 2.5 26.1 8.7 24.4 0.4 0.0 2.9 2.2 0.1 0.1 6.6 4.5 0.4 12.9 4.1 16.4 10.3 CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201287711 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 66.6" "Cell type enhanced" "Detected in many" "dendritic cells: 107.4;NK-cells: 132.8;Plasma cells: 73.4;T-cells: 86.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001302, CAB002047, HPA005688, HPA006191" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "CAB002047: AB_563465, HPA001302: AB_1846057, HPA005688: AB_1846056, HPA006191: AB_2667535" "unprognostic (5.21e-3)" "unprognostic (2.10e-1)" "unprognostic (1.83e-2)" "unprognostic (9.69e-3)" "unprognostic (2.09e-1)" "unprognostic (5.60e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.10e-1)" "unprognostic (4.79e-2)" "prognostic favorable (1.25e-4)" "unprognostic (7.75e-2)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (7.67e-3)" "unprognostic (2.43e-1)" "unprognostic (2.53e-1)" "unprognostic (4.53e-3)" 11.5 10.2 1.7 28.6 2.0 66.6 13.9 1.3 2.1 9.6 4.2 16.1 20.5 8.5 13.2 12.9 14.1 13.2 5.2 2.1 1.8 10.7 14.1 19.6 37.7 3.4 3.0 7.7 7.8 2.9 3.4 9.9 2.7 6.9 17.6 4.6 8.4 7.3 3.3 12.1 26.0 9.9 2.4 37.1 15.9 4.3 2.6 24.4 7.9 3.0 29.7 18.0 8.6 2.4 33.6 26.6 7.7 22.2 20.7 29.7 12.0 13.8 13.2 16.0 26.2 36.1 54.9 3.7 29.6 10.7 28.7 16.2 17.2 16.1 31.3 21.1 15.4 31.0 21.9 35.1 17.1 25.6 33.8 25.9 38.0 30.1 23.9 13.4 15.1 26.9 28.6 69.1 14.7 13.1 32.1 25.9 12.6 17.5 23.7 24.7 15.9 55.4 30.8 35.3 2.3 1.1 17.9 29.8 18.0 7.0 8.0 19.1 19.6 17.3 18.0 9.0 10.9 63.1 30.2 21.2 25.3 33.1 16.6 76.1 39.5 77.1 70.7 51.2 66.0 40.9 57.8 75.9 41.6 24.0 37.0 47.2 153.6 70.6 51.5 18.6 75.0 40.6 1.7 2.0 1.3 2.1 2.1 1.8 3.4 3.0 2.7 2.4 2.6 2.4 8.5 25.6 26.7 0.7 50.0 7.5 13.0 6.1 10.2 2.1 12.9 9.3 2.5 10.0 13.0 5.5 10.4 8.5 107.4 37.0 15.6 12.3 5.9 25.6 8.1 10.1 4.2 10.5 2.5 8.4 12.1 9.5 19.4 27.2 24.6 10.4 5.3 11.7 11.9 0.0 1.3 15.2 4.1 25.3 15.7 1.9 2.5 25.0 7.2 10.3 35.6 0.2 132.8 1.0 0.5 11.2 30.1 0.7 73.4 9.7 22.3 23.6 14.2 0.4 0.0 4.5 3.7 0.8 0.4 13.1 7.7 3.4 86.9 10.6 17.4 12.7 FLACC1 ALS2CR12 ENSG00000155749 "Flagellum associated containing coiled-coil domains 1" Q96Q35 2 201288271-201357398 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.8;testis: 17.1" "Cell type enriched" "Detected in single" 8 "Cardiomyocytes: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4;U-2197: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035793 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "HPA035793: AB_10602429" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.40e-3)" "unprognostic (1.40e-5)" "unprognostic (1.37e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-1)" "unprognostic (6.23e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (2.23e-1)" "unprognostic (8.25e-2)" 0.9 1.1 3.9 1.0 4.3 5.0 0.5 2.8 3.9 0.7 9.8 0.8 0.5 0.7 1.1 1.2 8.3 1.1 4.5 5.0 3.2 1.3 0.7 2.5 1.6 5.8 6.4 0.3 0.9 0.7 1.1 0.8 3.7 0.5 1.0 3.3 1.1 0.8 1.8 1.2 1.0 0.6 4.2 0.8 0.5 17.1 3.0 0.7 1.6 0.4 0.5 0.6 0.4 3.7 0.1 0.2 1.1 0.7 2.7 1.1 0.0 0.8 0.3 0.7 0.4 0.0 0.3 0.2 0.6 1.2 0.4 1.1 0.4 0.1 0.3 0.7 0.1 0.1 1.7 0.4 0.6 1.2 1.0 0.5 0.3 0.7 0.1 0.8 0.1 1.2 0.5 1.6 0.6 0.0 0.6 1.0 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.2 0.2 0.7 0.7 0.0 3.4 1.0 0.4 1.4 0.9 1.5 0.7 5.9 0.5 0.8 1.8 0.5 1.2 0.6 0.7 3.1 0.4 0.4 0.7 0.3 0.3 0.3 0.4 0.4 0.2 0.7 0.6 0.7 3.6 1.3 0.3 0.2 0.3 0.2 3.9 4.3 2.8 3.9 5.0 3.2 5.8 6.4 3.7 4.2 3.0 3.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 412.8;Proximal enterocytes: 124.0;Proximal tubular cells: 217.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 188.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026549, HPA028520" Approved Uncertain Aggresome,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol Aggresome "HPA026549: AB_1844779, HPA028520: AB_10604100" "unprognostic (6.34e-2)" "unprognostic (2.48e-1)" "unprognostic (2.63e-1)" "unprognostic (3.56e-3)" "unprognostic (4.04e-2)" "unprognostic (7.64e-2)" "unprognostic (1.35e-1)" "unprognostic (1.58e-1)" "unprognostic (2.63e-3)" "unprognostic (2.65e-2)" "unprognostic (6.21e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.08e-1)" "unprognostic (7.83e-2)" "prognostic favorable (4.45e-4)" "unprognostic (4.93e-2)" 29.9 53.2 24.1 8.9 26.3 80.9 16.8 26.2 30.8 10.6 22.4 27.6 37.0 13.2 17.4 17.0 10.4 14.3 38.0 25.3 26.2 73.3 104.9 10.6 14.5 27.7 25.9 14.1 17.6 6.2 17.4 19.7 27.3 11.1 30.3 40.5 13.9 7.7 109.0 8.4 42.9 10.2 26.7 13.7 9.1 15.8 25.6 11.4 17.9 69.5 11.6 9.7 9.3 30.2 12.6 21.5 36.2 47.0 58.5 73.8 25.6 25.6 43.4 34.9 51.6 29.6 11.9 0.1 16.0 40.7 42.4 12.6 35.8 23.9 62.7 14.9 30.1 15.2 9.6 62.9 43.9 18.4 16.7 62.5 21.6 43.7 39.0 63.5 26.5 28.5 33.4 5.3 188.5 6.8 17.2 31.1 49.2 11.7 22.6 22.8 14.5 9.6 29.2 9.9 6.0 29.3 17.6 13.1 76.8 66.0 6.7 34.4 25.7 20.6 16.1 26.6 19.3 21.1 39.0 5.8 35.8 8.2 20.5 5.5 12.9 16.3 9.2 14.4 8.3 28.8 12.2 13.4 17.2 35.8 15.5 15.6 2.6 29.0 13.1 7.7 16.4 15.8 24.1 26.3 26.2 30.8 25.3 26.2 27.7 25.9 27.3 26.7 25.6 30.2 5.0 9.6 4.2 17.0 20.2 2.2 6.8 6.5 11.4 13.8 24.9 10.8 27.8 28.6 6.1 14.7 83.4 51.0 6.3 40.9 39.2 12.4 3.9 7.5 7.4 5.6 16.9 412.8 20.8 15.4 27.6 13.6 6.6 10.2 5.7 12.0 7.9 94.6 19.2 11.8 19.8 22.6 8.2 16.9 5.2 8.1 10.8 13.5 16.0 15.0 14.8 19.6 7.2 26.7 26.0 9.0 35.2 3.8 10.9 10.2 124.0 217.8 5.3 19.1 6.6 21.7 6.6 45.0 46.7 15.2 1.4 27.9 8.9 26.8 25.0 9.1 C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 39.9" "Cell type enriched" "Detected in some" 21 "Theca cells: 41.0" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.9;HSkMC: 2.0;hTEC/SVTERT24-B: 2.0;SCLC-21H: 2.3;THP-1: 2.0;U-2197: 7.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" "unprognostic (2.64e-1)" "unprognostic (1.14e-1)" "unprognostic (8.77e-3)" "unprognostic (7.13e-6)" "unprognostic (1.33e-1)" "unprognostic (4.38e-2)" "unprognostic (2.16e-1)" "unprognostic (4.81e-2)" "unprognostic (3.15e-2)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (2.10e-1)" "unprognostic (5.13e-10)" "unprognostic (1.95e-1)" "unprognostic (6.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.18e-1)" 0.6 0.7 1.5 0.0 2.2 0.0 0.3 2.3 1.2 0.1 0.8 0.1 0.1 0.2 0.1 0.2 0.1 0.4 1.2 0.5 2.2 0.1 0.1 0.3 0.2 5.5 2.6 0.7 0.0 0.0 0.7 0.1 4.5 0.3 0.0 0.9 0.1 0.1 0.1 0.1 0.1 0.2 4.3 0.1 0.0 39.9 2.3 0.0 0.1 0.0 0.0 0.1 0.1 6.6 0.0 0.0 0.0 0.0 0.2 1.9 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.2 0.1 0.0 2.0 0.0 0.0 0.5 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 2.2 2.3 1.2 0.5 2.2 5.5 2.6 4.5 4.3 2.3 6.6 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 41.0 0.0 0.0 TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 89.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 81.7;Rod photoreceptor cells: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052596, HPA054732" Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 79: Retina - Phototransduction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA052596: AB_2681879, HPA054732: AB_2682587" "unprognostic (1.70e-1)" "unprognostic (7.10e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (2.51e-4)" "unprognostic (1.73e-1)" "unprognostic (4.06e-1)" "unprognostic (8.30e-6)" "unprognostic (4.15e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (7.96e-6)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 4.1 15.1 6.3 1.7 6.5 2.3 11.0 7.1 7.8 5.0 6.0 3.0 0.8 6.0 4.6 6.0 5.8 4.1 7.7 6.8 6.7 5.4 1.9 5.1 2.3 6.9 6.9 8.4 1.9 5.0 3.0 5.2 7.2 7.8 3.7 89.3 5.1 4.8 7.7 18.5 1.8 5.8 7.1 1.4 2.2 3.0 6.4 7.0 4.6 9.2 3.1 4.1 3.4 6.8 3.7 7.2 32.3 16.4 7.8 10.1 3.1 22.6 9.9 14.7 28.4 5.9 5.3 3.7 6.9 21.9 12.7 6.8 5.6 24.4 27.1 6.9 20.6 10.7 21.4 19.4 15.1 10.4 2.1 9.0 5.0 20.4 5.1 24.8 25.5 23.4 7.8 13.0 29.8 5.2 29.7 16.3 32.7 1.9 23.8 43.9 30.8 7.6 12.2 9.7 33.7 47.4 21.4 8.4 12.6 20.3 12.5 18.7 6.8 26.8 7.3 8.6 9.5 6.0 14.9 11.4 22.7 9.7 17.0 0.0 0.0 0.0 1.0 1.1 0.9 0.7 1.0 1.6 1.3 0.1 1.1 1.4 0.0 0.9 0.7 0.3 1.8 0.5 6.3 6.5 7.1 7.8 6.8 6.7 6.9 6.9 7.2 7.1 6.4 6.8 6.8 6.4 9.6 12.4 1.6 71.2 81.7 46.7 50.7 33.3 17.1 41.4 20.2 2.8 18.9 18.4 41.7 21.0 3.1 0.6 13.7 11.1 8.9 16.3 10.9 11.6 4.8 8.6 16.5 7.6 26.8 25.8 3.1 7.7 5.1 19.9 10.4 2.7 9.4 32.0 15.3 4.5 18.3 2.2 12.2 7.0 21.8 2.9 12.4 4.7 5.7 38.5 0.0 14.1 10.8 6.5 1.9 21.4 3.0 36.9 0.7 3.9 19.8 160.3 6.6 33.2 20.6 33.3 22.0 30.0 45.3 15.1 4.2 39.8 5.3 29.2 MPP4 DLG6 ENSG00000082126 "Membrane palmitoylated protein 4" Q96JB8 2 201644870-201698694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 194 "retina: 286.2" "Group enriched" "Detected in some" 36 "Cone photoreceptor cells: 1586.7;Rod photoreceptor cells: 808.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 22.2;hTEC/SVTERT24-B: 21.0;LHCN-M2: 85.8;TIME: 16.4;U-87 MG: 21.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "cerebellum: 2.7" HPA057393 Supported "Actin filaments,Cytosol" No No "Cluster 79: Retina - Phototransduction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Actin filaments" "HPA057393: AB_2732612" "unprognostic (1.42e-2)" "unprognostic (1.82e-2)" "unprognostic (2.55e-1)" "unprognostic (2.50e-2)" "unprognostic (2.22e-2)" "unprognostic (6.66e-2)" "unprognostic (1.09e-2)" "unprognostic (9.42e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-1)" "unprognostic (1.19e-1)" "unprognostic (9.20e-2)" "unprognostic (3.33e-16)" "unprognostic (1.82e-2)" "unprognostic (8.23e-2)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" 0.1 0.5 0.3 0.1 0.3 0.0 0.1 1.3 0.4 0.7 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 0.1 0.1 0.0 0.6 0.1 0.1 0.0 0.0 0.3 0.1 0.2 0.1 0.0 286.2 0.0 0.1 0.1 0.8 0.0 0.0 0.1 1.4 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.1 6.6 0.0 11.2 2.7 6.6 6.7 0.0 0.0 0.0 0.0 2.6 1.0 0.0 0.0 0.8 22.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.7 0.0 21.0 0.1 3.2 12.3 0.1 0.0 0.0 85.8 0.0 0.0 0.0 0.6 0.0 2.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 16.4 8.4 2.6 2.0 7.8 0.0 0.0 0.0 21.3 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 0.4 0.4 0.2 0.6 0.1 0.2 0.1 0.1 0.3 0.7 3.2 8.6 0.3 0.0 0.4 0.0 0.2 0.0 20.0 0.4 0.0 0.2 1.5 6.2 1.8 1586.7 0.1 0.2 0.0 0.0 0.2 2.8 0.4 0.4 2.6 0.0 0.0 7.3 0.2 0.1 0.6 0.0 0.1 3.8 0.1 0.0 0.1 0.1 18.5 2.8 0.0 0.0 0.3 0.9 2.5 0.0 0.4 1.8 0.0 0.1 33.0 1.0 2.0 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.1 6.7 808.3 0.0 1.4 1.1 0.1 0.4 0.0 0.4 0.0 0.3 0.1 0.2 0.0 ALS2 ALS2CR6 ENSG00000003393 "Alsin Rho guanine nucleotide exchange factor ALS2" Q96Q42 2 201700267-201782112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 91.8;granulocytes: 46.9;Inhibitory neurons: 66.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebellum: 26.4" "Group enriched" "Detected in many" 5 "basophil: 23.0;eosinophil: 6.8" "Lineage enriched" "Detected in all" 8 "granulocytes: 23.0" "Cell line enhanced" "Detected in all" "HMC-1: 50.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 87.8" HPA046588 Enhanced Approved "Intermediate filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Intermediate filaments, Cytosol" "HPA046588: AB_2679709" "unprognostic (3.43e-2)" "unprognostic (2.11e-1)" "unprognostic (1.33e-1)" "unprognostic (2.07e-3)" "unprognostic (2.72e-1)" "unprognostic (7.47e-2)" "unprognostic (1.04e-3)" "unprognostic (9.17e-2)" "unprognostic (4.16e-2)" "unprognostic (1.52e-1)" "unprognostic (2.99e-1)" "unprognostic (2.83e-2)" "unprognostic (1.09e-2)" "unprognostic (1.88e-1)" "unprognostic (1.61e-1)" "unprognostic (2.10e-1)" "unprognostic (1.84e-1)" 7.3 5.5 2.6 2.6 3.1 5.6 6.8 26.4 4.2 6.4 4.5 6.6 3.2 6.6 7.8 4.8 6.4 3.8 13.7 3.4 1.6 8.0 14.5 6.7 2.8 0.9 1.0 6.0 5.7 4.3 10.0 3.5 1.7 6.1 3.4 5.4 5.4 1.6 13.5 7.1 6.6 4.8 0.3 5.3 6.8 5.3 1.4 2.4 6.3 5.9 2.8 6.2 5.7 2.6 6.5 6.7 7.1 5.6 7.0 5.1 7.2 8.6 10.4 14.0 13.2 5.8 8.4 1.2 3.8 11.7 6.1 3.7 4.6 10.6 18.0 3.5 4.8 15.3 6.2 5.2 8.1 16.4 50.4 9.8 4.1 11.5 14.0 5.7 10.0 8.6 9.8 5.7 9.6 7.5 6.7 20.3 9.2 4.6 5.3 5.4 7.7 4.2 9.8 8.8 3.4 7.8 6.4 7.1 9.2 14.3 5.4 7.2 7.9 11.6 7.2 3.5 6.2 7.1 9.2 4.5 8.5 3.4 7.2 23.0 0.9 6.8 1.6 1.7 1.9 1.2 1.3 1.3 1.4 1.0 1.5 1.5 0.9 3.0 1.2 0.8 2.1 0.8 2.6 3.1 26.4 4.2 3.4 1.6 0.9 1.0 1.7 0.3 1.4 2.6 7.6 12.8 16.7 28.7 2.8 5.4 3.8 4.4 3.4 15.1 5.4 4.3 32.3 8.6 4.3 9.2 29.2 5.7 3.7 3.6 0.0 6.9 16.5 14.0 6.8 10.4 4.8 12.0 91.8 3.3 3.2 6.9 9.7 6.8 46.9 10.1 13.2 20.3 5.9 8.4 66.6 6.9 2.0 3.2 3.0 6.5 7.8 4.8 0.0 27.2 3.1 5.9 4.1 36.2 44.0 6.1 3.9 8.2 2.3 4.4 7.8 6.1 17.5 15.4 0.0 9.3 8.4 7.3 5.6 4.6 6.0 6.7 3.9 5.2 4.7 3.7 CDK15 "ALS2CR7, PFTAIRE2, PFTK2" ENSG00000138395 "Cyclin dependent kinase 15" Q96Q40 2 201790461-201895550 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 15.2;ovary: 6.1" "Group enriched" "Detected in some" 13 "Early spermatids: 27.1;granulocytes: 79.1;Late spermatids: 40.3" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Group enriched" "Detected in some" 28 "basophil: 1.8;eosinophil: 3.7" "Lineage enriched" "Detected in single" 37 "granulocytes: 3.7" "Cell line enhanced" "Detected in some" "BJ hTERT+: 22.6;BJ hTERT+ SV40 Large T+ RasG12V: 20.7;HBF TERT88: 30.9;HMC-1: 58.4;LHCN-M2: 19.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA015786 Uncertain Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Golgi apparatus" "HPA015786: AB_1844780" "unprognostic (2.51e-1)" "unprognostic (2.73e-1)" "unprognostic (2.84e-2)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (2.94e-1)" "unprognostic (4.79e-2)" "unprognostic (1.07e-1)" "unprognostic (1.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.64e-2)" "unprognostic (1.80e-2)" "unprognostic (7.38e-2)" "unprognostic (9.99e-5)" "unprognostic (6.31e-2)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" 0.7 0.3 0.0 0.2 0.0 0.0 0.8 2.4 0.4 0.8 0.0 0.5 0.3 0.6 15.2 0.6 0.5 1.9 0.2 0.5 0.0 0.3 0.0 1.0 0.1 0.4 0.1 6.1 0.1 0.2 0.3 0.0 0.4 0.7 0.7 0.0 0.3 0.3 0.9 0.6 0.8 0.4 0.1 0.0 0.7 1.9 0.1 0.2 0.1 0.7 0.1 0.8 0.5 0.3 0.3 0.0 0.0 0.0 1.6 2.8 0.0 5.9 22.6 10.2 20.7 0.0 3.0 0.0 0.0 2.3 0.5 0.0 0.0 0.0 30.9 0.0 0.1 1.9 0.0 0.0 0.3 0.1 58.4 3.4 0.0 2.7 1.5 0.4 0.0 0.0 0.0 0.1 19.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.5 2.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.4 0.5 0.0 0.4 0.1 0.4 0.1 0.1 0.3 0.1 0.0 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.8 0.0 0.0 79.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 40.3 0.3 0.1 3.6 1.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.5 0.2 0.0 0.1 0.0 0.9 0.1 0.0 0.0 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 KIAA2012 ENSG00000182329 KIAA2012 2 202073255-202205188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 6.9;choroid plexus: 3.1;fallopian tube: 9.2" "Group enriched" "Detected in some" 6 "Early spermatids: 38.9;Endometrial ciliated cells: 12.3;Excitatory neurons: 24.8;Late spermatids: 28.6;Respiratory ciliated cells: 43.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077834 Enhanced NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 49: Ciliated cells - Cilium organization" "HPA077834: " "unprognostic (1.91e-2)" "unprognostic (3.17e-1)" "unprognostic (2.56e-1)" "unprognostic (5.35e-2)" "unprognostic (2.85e-2)" "unprognostic (3.22e-2)" "unprognostic (1.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "unprognostic (7.35e-2)" "unprognostic (6.31e-2)" "unprognostic (7.81e-2)" "unprognostic (6.94e-5)" "unprognostic (1.60e-1)" "unprognostic (9.44e-2)" "unprognostic (3.37e-1)" "unprognostic (9.95e-3)" 0.0 0.0 1.0 0.0 2.0 0.0 0.0 0.1 1.3 0.3 3.1 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 1.9 1.1 0.0 0.9 0.8 0.0 5.6 6.9 0.0 0.0 0.0 0.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.7 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.0 0.1 1.3 1.9 1.1 5.6 6.9 3.1 4.9 1.9 0.9 0.2 3.2 0.0 1.0 0.1 0.0 0.3 0.0 0.0 2.9 0.4 0.1 1.0 0.0 1.8 0.0 2.1 0.1 0.2 0.0 0.0 0.0 38.9 12.3 0.6 0.4 0.0 0.0 24.8 0.2 0.1 0.6 0.0 0.6 0.0 0.2 1.1 4.8 0.1 3.3 2.8 0.0 0.0 0.0 0.0 28.6 0.0 0.2 0.0 0.0 0.0 0.3 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.3 0.2 0.0 43.0 2.4 0.0 0.8 0.2 1.5 3.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 SUMO1 "GMP1, OFC10, PIC1, SMT3C, SMT3H3, SUMO-1, UBL1" ENSG00000116030 "Small ubiquitin like modifier 1" P63165 2 202206182-202238599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 7.6" "CAB004269, HPA056956" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Nuclear bodies" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear membrane" "Nucleoli, Nuclear bodies" "CAB004269: AB_628300, HPA056956: AB_2683285" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.49e-1)" "unprognostic (2.52e-3)" "unprognostic (2.89e-1)" "unprognostic (9.56e-3)" "unprognostic (1.76e-2)" "unprognostic (8.08e-2)" "unprognostic (1.78e-3)" "prognostic favorable (7.93e-4)" "unprognostic (7.06e-3)" "unprognostic (1.16e-1)" "unprognostic (4.64e-3)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" "unprognostic (2.82e-2)" "unprognostic (2.19e-1)" 77.5 99.1 79.4 62.7 84.9 133.7 83.6 89.0 99.9 68.9 84.4 82.7 72.0 65.1 86.3 71.6 65.7 71.7 79.8 85.6 85.3 118.1 174.1 66.5 86.4 79.9 80.1 54.5 55.8 91.6 56.7 75.6 81.1 75.3 82.8 80.2 66.8 61.9 107.5 57.1 80.5 71.5 78.9 68.1 73.8 54.7 81.4 112.1 102.3 103.3 95.4 77.9 54.9 86.6 164.1 82.4 291.4 155.8 159.3 168.5 129.7 171.0 214.6 209.0 274.6 178.1 203.7 111.6 153.5 199.0 193.5 117.1 242.2 237.9 325.0 104.8 185.7 207.6 159.0 211.2 114.9 237.2 188.5 130.9 225.2 164.0 123.9 195.1 197.3 219.0 194.2 176.0 226.4 141.1 298.3 391.6 351.7 168.5 172.2 190.9 163.2 197.9 255.5 134.3 201.7 219.3 140.3 133.6 236.4 313.9 120.0 223.2 139.9 152.5 153.0 141.4 152.8 151.7 322.9 285.8 170.2 165.4 137.2 242.2 220.0 284.2 169.2 226.5 179.6 276.3 206.8 200.0 223.6 231.6 193.8 202.3 256.5 246.5 239.7 187.8 329.0 394.7 79.4 84.9 89.0 99.9 85.6 85.3 79.9 80.1 81.1 78.9 81.4 86.6 182.7 112.2 61.1 10.7 143.1 422.1 204.4 448.6 177.6 99.6 196.8 170.2 58.1 130.1 215.3 189.4 64.6 259.4 162.3 136.6 481.3 250.4 91.3 148.3 115.1 170.7 142.4 140.1 31.4 173.3 297.8 161.8 89.7 115.2 92.6 114.7 142.8 202.1 205.3 87.5 27.8 156.4 319.4 140.7 330.2 28.0 129.8 137.7 211.7 15.9 241.3 182.3 176.1 16.6 21.2 208.1 191.1 127.9 130.5 258.5 272.2 534.4 185.5 87.8 111.7 92.5 221.9 212.0 141.5 183.9 424.5 209.7 174.5 134.9 157.5 254.1 NOP58 "HSPC120, NOP5" ENSG00000055044 "NOP58 ribonucleoprotein" Q9Y2X3 2 202265736-202303661 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018472, HPA021062" Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" NA Yes "Cluster 15: NK-cells - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli fibrillar center" Nucleoplasm "HPA018472: AB_1854564, HPA021062: AB_1854565" "unprognostic (1.56e-2)" "unprognostic (1.61e-1)" "unprognostic (9.20e-2)" "unprognostic (2.15e-3)" "unprognostic (2.39e-1)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.97e-6)" "unprognostic (6.64e-2)" "unprognostic (1.17e-2)" "prognostic favorable (9.86e-4)" "unprognostic (4.52e-3)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.38e-9)" "unprognostic (1.79e-2)" "unprognostic (3.10e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" 36.0 35.1 33.5 43.9 33.6 76.3 43.7 38.8 58.4 29.5 33.4 30.4 28.2 32.2 33.4 37.8 31.6 23.6 25.1 33.4 36.3 32.8 40.7 26.4 60.3 32.3 33.3 37.4 37.8 24.8 30.2 32.6 32.6 29.5 35.8 28.1 26.5 23.1 41.8 30.7 29.7 27.3 32.6 33.9 29.6 24.9 34.8 41.9 27.1 21.5 59.8 43.3 30.2 35.3 126.4 86.0 85.1 106.8 62.0 55.6 199.2 118.5 62.9 89.1 82.9 191.5 110.9 193.1 95.4 72.5 111.6 114.0 170.1 144.7 158.4 75.0 152.5 233.6 133.3 193.7 91.5 234.7 108.6 72.1 85.3 124.6 284.6 48.6 81.2 112.3 260.4 144.1 113.4 131.4 215.1 258.7 212.9 139.4 146.5 179.5 128.3 257.1 107.1 148.5 130.5 95.8 109.0 156.6 140.8 136.2 106.4 181.8 70.3 113.5 133.8 102.5 206.0 115.7 226.1 274.8 84.2 163.7 138.5 13.4 24.0 7.4 37.2 35.6 55.0 56.1 53.1 51.2 37.4 45.0 57.5 58.9 2.3 52.1 28.3 53.1 58.0 32.5 33.5 33.6 38.8 58.4 33.4 36.3 32.3 33.3 32.6 32.6 34.8 35.3 56.3 109.0 116.2 22.2 111.6 85.8 150.5 98.0 78.0 28.1 53.8 70.2 82.7 37.1 116.8 40.5 41.7 78.1 87.1 35.7 29.4 59.9 39.2 59.6 75.9 62.3 35.2 65.2 39.0 67.8 96.9 82.6 51.0 97.0 137.3 47.7 32.2 46.1 47.7 25.2 47.5 61.5 61.1 23.2 43.5 11.1 43.2 51.5 24.9 20.6 59.6 18.8 35.0 20.6 27.0 50.3 17.3 29.7 118.6 89.9 18.3 37.8 70.6 44.2 26.3 112.2 116.8 70.4 58.4 77.5 74.7 68.0 124.1 45.4 79.6 94.6 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 45.8;Inhibitory neurons: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Centrosome "HPA003229: AB_2246696, HPA028746: AB_2672760" "unprognostic (1.39e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (4.59e-2)" "unprognostic (1.07e-2)" "unprognostic (4.07e-3)" "unprognostic (1.55e-2)" "unprognostic (4.84e-2)" "unprognostic (6.21e-2)" "unprognostic (2.55e-2)" "unprognostic (8.40e-3)" "unprognostic (5.75e-1)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (3.18e-1)" "unprognostic (8.59e-2)" "unprognostic (1.37e-3)" 3.1 7.5 5.1 4.5 5.4 2.9 3.3 7.0 7.1 2.7 0.7 4.9 4.3 2.9 2.9 5.4 3.8 3.0 1.8 5.0 6.3 4.9 1.9 2.9 7.2 3.1 3.8 5.1 4.6 7.3 3.5 6.9 3.6 5.1 4.7 2.6 3.3 3.0 1.5 5.0 3.7 2.0 3.3 5.4 4.1 5.8 6.4 9.6 2.8 1.8 7.4 3.8 3.2 4.1 2.0 2.4 10.5 7.2 3.5 1.9 10.2 0.6 0.9 0.6 1.1 3.1 4.2 8.2 6.5 1.2 1.6 1.9 9.0 4.6 1.7 0.2 7.2 6.9 4.3 11.6 2.8 5.9 3.0 2.6 6.3 1.3 1.9 4.7 2.8 10.8 10.1 1.6 0.6 3.9 16.1 12.1 10.7 5.8 4.5 12.5 2.1 9.8 5.5 5.2 17.7 15.4 8.0 5.3 3.9 8.7 2.2 8.1 1.7 1.2 2.4 1.9 1.1 5.9 3.6 10.8 2.4 4.5 1.3 0.4 3.9 1.5 1.3 8.2 3.4 8.1 3.0 2.7 4.5 7.7 8.2 5.7 2.2 4.4 9.1 1.5 1.2 3.1 5.1 5.4 7.0 7.1 5.0 6.3 3.1 3.8 3.6 3.3 6.4 4.1 9.7 3.2 7.5 13.1 21.5 17.2 2.9 3.0 12.0 4.9 8.1 4.3 4.9 12.8 2.6 18.4 4.2 8.4 8.8 11.7 0.0 10.2 2.2 8.6 6.5 4.9 25.8 3.0 45.8 6.4 6.3 6.1 7.1 10.1 5.7 15.3 8.2 2.2 2.8 6.7 49.7 11.8 2.0 27.4 13.9 1.4 13.1 17.1 3.6 23.4 17.1 1.7 3.1 29.1 29.4 5.8 9.7 23.7 5.2 6.7 4.9 5.9 3.0 2.7 6.6 2.0 4.1 5.0 16.3 29.2 19.9 2.7 10.1 11.1 13.8 6.0 ICA1L "ALS2CR14, ALS2CR15" ENSG00000163596 "Islet cell autoantigen 1 like" Q8NDH6 2 202773150-202871766 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.7;Inhibitory neurons: 114.3;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 84.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 21.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042507 Approved Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 58: Brain - Synaptic function" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria "HPA042507: AB_10797016" "unprognostic (4.14e-3)" "unprognostic (3.60e-3)" "unprognostic (5.15e-2)" "unprognostic (5.63e-3)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-4)" "unprognostic (1.66e-1)" "unprognostic (9.60e-2)" "unprognostic (4.50e-4)" "unprognostic (4.15e-1)" "unprognostic (8.15e-3)" "unprognostic (2.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.58e-3)" 3.8 4.8 9.8 1.3 12.0 3.9 3.5 23.2 20.6 7.1 7.4 6.8 1.5 7.5 5.7 2.6 9.5 3.6 4.9 13.4 13.7 3.2 0.5 2.2 1.5 3.7 5.5 8.1 2.7 7.1 15.7 5.2 1.6 5.5 1.6 17.5 1.9 6.1 5.1 1.9 2.0 4.6 3.3 1.4 3.7 8.3 9.9 2.7 5.1 6.7 1.2 5.4 3.4 8.7 1.5 1.2 2.9 8.4 2.7 5.0 21.8 2.9 3.8 1.6 2.3 1.4 0.6 1.7 0.8 3.5 4.6 0.8 4.0 1.4 2.1 1.5 3.1 3.6 1.8 1.8 1.5 4.4 2.1 1.9 2.4 1.7 1.4 4.9 2.4 5.6 2.8 1.6 2.5 0.7 3.6 6.0 8.4 0.5 3.1 4.3 4.4 0.7 1.6 3.9 7.8 7.5 4.5 0.2 1.9 2.4 1.0 3.4 1.6 7.0 1.8 1.5 4.4 5.5 8.9 4.5 4.0 1.4 1.3 1.2 1.1 0.6 0.9 1.2 0.7 1.3 0.8 0.7 1.6 2.3 1.1 1.6 1.5 2.3 2.1 1.1 0.7 0.7 9.8 12.0 23.2 20.6 13.4 13.7 3.7 5.5 1.6 3.3 9.9 8.7 13.0 9.6 10.0 62.0 10.5 2.0 4.4 2.9 1.2 58.7 4.1 2.8 15.2 1.5 8.7 18.4 60.5 16.3 5.7 1.0 0.0 5.3 28.7 40.9 17.0 5.8 19.2 2.5 171.7 4.9 37.7 12.0 3.6 9.9 6.3 17.4 5.7 1.1 3.6 16.8 114.3 2.1 4.1 5.3 9.7 40.2 31.7 5.2 7.2 15.9 3.8 22.1 17.5 93.5 42.7 3.4 0.6 46.3 2.1 5.2 1.9 3.7 36.7 84.1 0.0 10.0 6.3 34.1 8.8 1.9 2.3 7.5 7.3 6.0 1.7 2.7 WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoli "HPA036389: AB_10670716" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "unprognostic (8.17e-2)" "unprognostic (3.59e-3)" "unprognostic (1.24e-2)" "unprognostic (9.40e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (1.52e-1)" "unprognostic (6.14e-2)" "unprognostic (4.78e-2)" "unprognostic (4.58e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.66e-1)" "unprognostic (9.69e-3)" "unprognostic (4.48e-2)" 2.6 3.6 2.1 2.7 2.3 3.6 3.6 2.3 3.2 2.5 1.4 3.0 4.1 3.2 3.2 3.2 3.1 2.3 4.0 2.2 2.9 5.2 4.2 1.7 3.3 2.5 2.1 3.2 2.2 3.5 1.9 2.7 2.7 2.2 4.0 2.6 1.9 2.3 4.8 3.6 2.9 3.4 1.5 2.1 2.3 3.5 2.8 3.2 3.2 6.0 3.7 4.1 2.3 2.5 5.3 5.8 6.4 12.5 12.3 10.4 11.4 7.6 6.6 10.1 9.8 14.8 7.5 10.2 7.2 6.6 8.5 6.6 18.2 13.3 16.0 4.6 11.1 17.0 9.0 17.7 8.0 22.1 9.9 9.5 9.4 12.0 23.6 6.4 10.8 10.2 26.7 5.9 11.3 6.5 14.8 13.3 14.9 7.3 14.3 11.1 9.7 16.1 11.2 6.5 11.4 9.8 6.5 8.2 9.8 11.0 4.7 14.1 8.3 8.3 6.9 7.4 8.4 8.0 12.8 16.3 8.7 15.3 8.8 1.3 1.6 0.6 1.4 1.7 2.0 1.9 1.3 1.4 2.1 1.9 1.7 1.7 0.6 1.3 1.7 2.4 1.6 1.1 2.1 2.3 2.3 3.2 2.2 2.9 2.5 2.1 2.7 1.5 2.8 2.5 10.1 9.6 16.9 12.1 13.6 20.5 21.4 24.4 13.1 10.2 8.4 9.1 27.9 7.2 19.1 5.5 2.1 25.3 7.9 7.8 15.6 18.0 14.3 14.7 25.3 12.6 5.4 22.1 19.2 10.6 34.9 16.5 9.7 13.3 15.2 15.8 8.2 15.0 18.0 15.2 20.3 10.6 24.4 7.2 6.0 8.9 17.1 9.2 1.8 12.2 13.7 6.4 5.2 10.6 9.9 14.2 6.6 15.4 9.3 17.3 13.9 38.1 15.7 8.3 13.1 20.1 41.9 43.0 32.3 18.2 17.3 21.5 10.7 21.0 19.2 17.0 CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: AB_10601663, HPA043191: AB_2732503" "unprognostic (4.63e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.93e-2)" "unprognostic (6.09e-2)" "unprognostic (8.65e-3)" "unprognostic (1.12e-1)" "unprognostic (2.13e-3)" "unprognostic (4.39e-2)" "unprognostic (1.10e-1)" "unprognostic (7.58e-3)" "unprognostic (1.08e-1)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" 4.5 5.3 4.2 5.7 8.6 5.4 7.7 6.4 5.1 5.9 2.5 5.2 4.5 9.4 9.9 5.5 6.8 6.0 4.9 4.4 5.0 6.8 4.5 5.1 8.8 5.9 6.0 7.9 3.9 7.8 5.1 4.7 6.5 6.7 6.0 16.1 4.6 6.4 4.5 7.4 4.9 6.6 4.6 7.5 6.0 21.5 5.5 9.4 10.6 5.4 7.8 5.7 5.0 12.3 2.5 2.4 6.1 5.4 4.5 9.5 4.7 3.7 4.7 3.8 3.4 2.8 6.2 3.8 1.6 4.3 4.6 4.5 3.2 2.7 4.3 3.0 1.7 5.9 3.0 1.7 3.8 3.5 2.9 7.8 5.2 3.3 8.6 9.6 2.3 13.9 2.5 15.5 5.9 4.9 7.2 5.6 2.6 1.6 3.5 5.1 4.2 3.1 6.9 2.6 4.3 4.6 4.0 2.2 1.7 7.7 3.6 6.5 2.7 7.1 1.8 4.6 2.4 13.7 8.4 4.2 6.1 4.1 4.4 1.4 1.0 0.8 2.2 1.9 2.4 2.0 2.2 2.1 1.2 2.4 3.1 2.2 0.4 8.8 1.1 1.9 4.7 0.6 4.2 8.6 6.4 5.1 4.4 5.0 5.9 6.0 6.5 4.6 5.5 12.3 5.6 9.6 15.7 28.7 14.6 3.2 3.9 5.5 5.2 33.5 6.7 5.5 6.6 7.2 14.1 14.7 18.8 4.2 9.2 2.7 11.7 4.4 19.0 7.1 5.0 5.6 1.8 7.6 21.5 2.4 9.3 7.4 5.6 2.9 20.3 19.6 8.2 3.2 3.9 26.9 25.0 4.7 6.1 8.2 3.7 16.7 10.8 4.9 1.8 16.9 5.9 9.6 18.6 39.2 66.1 2.9 3.2 9.4 4.0 2.0 9.5 5.8 17.7 31.1 6.6 7.1 5.6 37.2 8.6 4.4 2.7 1.8 10.2 10.5 6.2 2.7 NBEAL1 "ALS2CR16, ALS2CR17, MGC164581" ENSG00000144426 "Neurobeachin like 1" Q6ZS30 2 203014879-203226378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1030.4;Langerhans cells: 1016.1;Suprabasal keratinocytes: 1304.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049189, HPA049447" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 15: RT4 - Unknown function" "Cluster 32: Non-specific - Translation" Nucleoplasm Cytosol "HPA049189: AB_2680669, HPA049447: AB_2680771" "unprognostic (3.66e-2)" "unprognostic (5.26e-2)" "unprognostic (2.86e-2)" "unprognostic (1.11e-1)" "unprognostic (4.52e-4)" "unprognostic (1.16e-1)" "unprognostic (1.92e-1)" "unprognostic (1.20e-1)" "unprognostic (4.40e-2)" "unprognostic (6.77e-3)" "unprognostic (2.01e-3)" "unprognostic (7.20e-2)" "unprognostic (2.56e-3)" "unprognostic (2.12e-1)" "unprognostic (2.22e-1)" "unprognostic (7.98e-3)" "unprognostic (7.59e-2)" 3.0 2.1 1.5 1.7 3.3 1.1 3.3 4.1 1.9 2.7 8.5 6.9 4.6 2.6 2.1 2.1 3.4 3.1 2.6 1.2 2.2 6.5 5.7 4.4 1.1 2.7 2.2 3.7 2.9 2.9 0.9 2.8 2.7 2.2 6.7 3.9 1.7 1.8 1.5 2.2 5.5 2.7 1.6 1.7 7.1 3.6 2.6 1.3 4.6 3.9 1.3 2.9 1.7 3.6 4.2 3.9 1.6 1.4 9.7 7.5 2.3 4.0 2.9 2.1 3.2 4.4 2.1 0.9 3.2 6.8 4.1 3.4 3.2 4.7 4.8 1.9 1.4 1.6 6.0 2.5 2.3 1.5 1.8 2.9 3.0 3.4 4.2 5.0 3.3 1.7 2.9 1.4 4.8 2.9 0.6 0.8 0.8 1.8 3.6 0.7 2.6 1.0 5.8 7.8 1.0 0.8 3.4 2.5 2.5 3.9 2.9 1.5 5.7 5.5 4.6 2.6 1.8 2.4 1.9 1.2 3.3 0.6 1.9 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 1.5 3.3 4.1 1.9 1.2 2.2 2.7 2.2 2.7 1.6 2.6 3.6 53.0 38.5 72.2 103.5 145.5 1030.4 399.8 231.1 117.8 18.4 81.2 89.2 21.4 223.1 94.4 38.6 27.1 205.9 58.8 173.8 84.1 57.4 30.9 57.8 73.5 155.1 293.5 49.0 88.0 99.2 276.5 154.4 103.9 69.3 107.2 43.3 287.0 203.7 154.5 82.4 79.7 515.3 91.6 531.4 1016.1 49.5 274.3 78.0 629.7 81.5 186.0 19.5 171.9 105.1 130.9 78.5 335.8 129.4 52.4 304.8 343.9 103.1 59.2 26.9 118.3 388.6 265.6 45.1 41.2 118.4 1304.2 229.3 182.3 31.4 528.3 305.2 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 ABI2 "ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2" ENSG00000138443 "Abl interactor 2" Q9NYB9 2 203328280-203447728 "Predicted intracellular proteins" "Host-virus interaction, Neurogenesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070567 Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA070567: AB_2686281" "unprognostic (5.26e-3)" "unprognostic (5.26e-3)" "unprognostic (1.86e-1)" "unprognostic (4.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (1.81e-3)" "unprognostic (7.05e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-3)" "unprognostic (6.19e-3)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.24e-2)" "unprognostic (2.94e-1)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" 10.5 13.2 31.0 9.5 41.9 3.3 15.2 22.9 38.4 19.0 10.0 18.7 5.7 28.0 18.7 11.9 22.5 13.4 32.7 40.4 33.0 20.9 7.4 16.1 8.2 16.3 24.1 27.9 7.5 20.4 20.5 19.4 17.3 18.7 10.7 30.0 8.6 23.0 7.4 7.6 8.9 25.2 21.3 12.9 9.3 27.5 36.0 22.2 26.5 15.8 8.7 14.6 11.9 22.5 19.3 29.4 102.5 64.4 23.9 40.5 22.6 33.0 29.0 27.9 32.2 27.3 35.5 0.0 22.0 39.0 38.8 20.9 47.1 34.6 54.8 9.5 27.4 47.9 30.9 21.4 36.3 20.6 21.1 28.8 16.5 51.2 39.5 80.5 52.6 54.1 34.7 41.8 49.7 35.0 52.8 20.4 53.5 18.2 64.8 34.5 51.4 3.5 29.3 19.6 43.2 55.3 6.2 19.2 37.4 76.8 25.0 23.9 39.9 50.4 43.0 27.8 36.2 29.3 28.7 26.6 54.7 8.5 33.2 0.2 1.4 0.0 3.3 1.6 3.6 1.4 3.7 3.7 4.0 1.3 4.4 3.9 0.2 3.9 3.8 12.7 4.4 3.2 31.0 41.9 22.9 38.4 40.4 33.0 16.3 24.1 17.3 21.3 36.0 22.5 39.7 54.5 26.5 123.4 14.7 30.1 55.7 37.7 34.1 111.9 39.5 38.7 56.7 28.6 32.8 53.3 162.6 23.7 33.1 10.1 33.2 24.3 128.2 62.3 68.4 43.6 49.2 30.3 201.3 13.1 15.7 54.1 25.0 72.3 15.8 100.0 65.7 12.3 16.7 102.6 128.6 10.9 20.3 11.4 62.3 81.6 46.6 22.1 49.8 57.1 18.6 67.6 26.8 114.1 94.2 15.5 19.4 63.2 18.3 44.2 11.1 38.5 83.1 89.6 26.3 70.5 67.9 89.0 52.4 22.0 26.1 19.7 21.7 69.9 17.0 37.5 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 CD28 ENSG00000178562 "CD28 molecule" P10747 2 203706475-203738912 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 30.8;placenta: 14.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 34.1;T-cells: 52.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 101.9" "Lineage enriched" "Detected in many" 7 "T-cells: 101.9" "Group enriched" "Detected in some" 14 "Karpas-707: 360.6;RPMI-8226: 173.2;U-266/70: 294.1;U-266/84: 283.7" "Region enhanced" "Detected in single" "olfactory bulb: 1.0" "Not detected" "Not detected" HPA070003 Enhanced NA NA "Cluster 13: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "HPA070003: AB_2686226" "unprognostic (5.54e-2)" "unprognostic (2.16e-4)" "unprognostic (1.90e-3)" "unprognostic (2.49e-3)" "unprognostic (3.44e-2)" "unprognostic (6.07e-5)" "unprognostic (9.09e-2)" "unprognostic (4.66e-2)" "unprognostic (3.40e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-1)" "unprognostic (1.68e-1)" "unprognostic (5.78e-5)" "unprognostic (4.77e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (8.96e-2)" 4.0 0.3 0.0 14.9 0.1 3.3 0.8 0.1 0.1 1.1 0.9 1.7 1.1 0.7 0.3 0.9 0.5 4.1 0.6 0.1 0.1 0.5 1.3 1.9 28.0 0.1 0.0 0.3 0.5 0.2 0.1 14.8 0.1 1.0 1.9 0.1 0.6 0.8 0.3 0.3 3.0 1.4 0.1 7.2 2.5 0.7 0.2 30.8 0.5 0.1 18.6 4.6 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.1 0.7 2.0 0.0 360.6 0.2 0.0 19.9 0.0 0.1 0.0 0.0 0.1 0.3 173.2 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.1 0.3 294.1 283.7 2.9 0.3 0.1 0.0 1.7 0.6 1.0 8.3 0.5 50.6 0.3 54.5 26.1 0.1 0.3 48.1 18.6 13.8 0.2 0.5 0.2 101.9 14.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.5 0.0 1.3 0.0 2.4 2.9 0.1 0.0 0.6 0.0 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 3.2 0.1 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.1 0.0 0.3 1.0 2.0 0.1 1.3 0.0 0.0 0.1 34.1 0.0 0.0 0.0 0.0 0.8 5.3 0.2 0.0 4.4 0.0 1.0 1.5 0.0 2.1 0.0 0.1 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.1 0.2 1.6 0.1 52.6 0.0 0.0 0.0 CTLA4 "CD, CD152, CELIAC3, CTLA-4, GSE, IDDM12" ENSG00000163599 "Cytotoxic T-lymphocyte associated protein 4" P16410 2 203867771-203873965 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Diabetes mellitus, Disease variant, FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 37.4" "Cell type enriched" "Detected in some" 8 "T-cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 7 "T-reg: 44.5" "Lineage enriched" "Detected in single" 445 "T-cells: 44.5" "Cell line enhanced" "Detected in some" "Karpas-707: 1.5;SK-MEL-30: 3.0;U-266/70: 4.3;U-266/84: 13.5" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.92e-2)" "unprognostic (9.13e-3)" "unprognostic (1.47e-3)" "unprognostic (9.89e-6)" "unprognostic (1.86e-1)" "prognostic favorable (4.48e-5)" "unprognostic (1.02e-1)" "unprognostic (1.75e-2)" "unprognostic (1.84e-3)" "unprognostic (2.65e-3)" "unprognostic (2.77e-1)" "unprognostic (3.76e-1)" "unprognostic (9.86e-10)" "unprognostic (4.13e-2)" "unprognostic (7.45e-2)" "unprognostic (4.94e-2)" "unprognostic (1.19e-2)" 1.1 0.2 0.4 18.5 0.4 6.1 1.0 0.4 0.7 0.6 0.5 1.3 0.3 0.3 0.0 1.6 0.6 5.2 0.5 0.5 0.5 0.6 0.7 2.9 37.4 1.3 0.7 0.1 0.4 0.5 0.3 0.3 1.1 1.5 3.2 0.0 0.5 1.0 0.1 0.7 6.2 0.8 0.6 3.9 2.9 1.1 0.5 10.1 1.1 0.2 17.0 5.8 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 4.3 13.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 6.2 0.8 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 44.5 0.6 0.4 0.4 0.4 0.7 0.5 0.5 1.3 0.7 1.1 0.6 0.5 0.5 0.4 0.0 3.2 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 4.1 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 3.3 0.0 2.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 1.0 0.2 0.9 0.1 41.9 0.0 0.0 0.1 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 PARD3B "ALS2CR19, PAR3beta, Par3L" ENSG00000116117 "Par-3 family cell polarity regulator beta" Q8TEW8 2 204545475-205620162 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 490.7;Microglial cells: 183.6;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;BJ hTERT+: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035283 Approved Supported "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions" "HPA035283: AB_10671102" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.67e-10)" "unprognostic (1.74e-1)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (8.09e-2)" 9.1 2.8 6.0 1.7 7.3 0.0 5.5 5.3 5.3 4.9 9.3 12.6 3.6 5.1 3.7 4.0 6.5 4.5 4.0 4.6 9.2 6.9 3.4 5.4 2.1 9.3 12.2 7.3 4.9 9.2 1.9 4.4 8.3 4.8 5.5 2.5 3.0 5.2 2.7 4.5 4.2 5.2 8.4 3.1 4.5 3.8 8.0 1.4 5.6 3.6 2.5 5.9 4.0 7.4 2.5 2.1 6.3 2.3 17.8 8.9 3.4 3.8 12.5 3.5 3.8 6.2 1.7 0.0 4.3 7.8 2.8 0.3 0.8 1.0 3.6 0.2 2.9 8.8 5.2 0.0 1.8 0.0 0.5 3.4 1.7 1.2 5.2 5.3 5.2 0.8 0.2 0.1 4.5 1.0 0.0 0.0 0.8 0.9 0.5 0.0 2.7 2.1 3.7 2.5 0.7 2.0 2.0 1.9 1.7 6.2 3.1 0.0 10.9 2.7 1.7 5.5 1.8 0.0 0.0 0.0 2.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.3 5.3 5.3 4.6 9.2 9.3 12.2 8.3 8.4 8.0 7.4 9.5 9.6 8.6 490.7 0.5 11.0 3.3 2.4 6.8 0.5 5.6 5.8 10.8 15.7 14.5 29.5 0.0 3.2 0.2 12.4 0.0 8.7 76.6 8.5 4.0 6.8 6.0 0.8 5.6 2.4 0.2 16.2 11.7 7.4 1.3 14.1 8.2 4.5 0.5 5.0 50.8 9.2 2.0 1.0 4.3 26.0 31.1 0.6 7.2 183.6 0.1 9.7 0.0 159.3 104.2 6.5 15.9 57.9 1.4 5.0 9.4 4.8 17.0 0.3 19.7 23.5 9.6 1.4 2.9 3.5 4.7 1.1 1.0 2.3 8.0 5.3 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 INO80D FLJ20309 ENSG00000114933 "INO80 complex subunit D" Q53TQ3 2 205993721-206086303 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.9" "Cell type enhanced" "Detected in all" "Astrocytes: 158.7;Excitatory neurons: 127.7;Inhibitory neurons: 129.0;Oligodendrocytes: 188.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043976 Approved NA NA "Cluster 6: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "HPA043976: AB_10960835" "unprognostic (6.79e-2)" "unprognostic (9.77e-2)" "unprognostic (1.34e-1)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "prognostic favorable (5.53e-4)" "unprognostic (4.83e-3)" "unprognostic (3.00e-1)" "unprognostic (8.10e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" "unprognostic (1.39e-2)" "unprognostic (4.05e-3)" "unprognostic (1.30e-1)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (3.03e-2)" 4.6 3.0 0.7 2.3 1.1 17.9 4.3 5.3 1.4 4.3 1.0 3.9 3.4 4.0 1.4 4.4 3.9 3.0 3.6 0.5 0.6 3.0 3.7 4.1 4.4 1.4 0.5 5.1 4.1 1.4 4.0 2.5 0.8 3.4 1.4 5.1 4.2 0.9 5.7 6.1 4.7 1.0 0.0 3.9 3.8 5.6 1.1 1.7 5.2 1.7 1.7 3.6 4.5 3.0 2.4 1.8 4.5 3.6 1.3 1.6 3.3 1.8 0.9 1.3 1.0 3.6 4.7 2.4 2.9 1.1 4.5 3.2 1.7 1.2 1.5 2.1 3.3 5.2 4.2 4.4 0.8 4.5 3.3 1.0 1.6 1.6 2.1 3.5 1.7 2.9 5.1 5.6 1.4 3.2 2.5 14.8 6.0 1.4 2.6 3.1 2.8 2.6 1.3 4.1 4.1 3.9 3.3 2.1 3.5 3.6 2.9 4.4 4.7 3.7 3.6 1.6 2.2 7.0 5.7 6.1 2.9 3.9 2.8 4.1 2.2 2.0 3.0 1.2 2.5 4.1 2.2 1.4 1.6 5.2 2.5 1.9 5.1 2.0 3.4 4.5 2.6 0.9 0.7 1.1 5.3 1.4 0.5 0.6 1.4 0.5 0.8 0.0 1.1 3.0 31.5 22.4 34.7 158.7 35.5 30.8 18.2 9.8 25.6 39.5 19.9 13.8 17.5 31.5 18.6 18.4 39.6 8.4 43.0 27.3 5.9 13.5 3.7 25.3 31.4 27.8 25.2 29.9 127.7 13.1 5.9 29.4 26.5 41.2 32.4 24.1 17.2 16.3 11.7 11.8 129.0 20.3 4.1 21.7 28.9 5.4 20.2 23.1 17.8 117.1 25.9 16.8 26.8 126.2 188.3 17.8 19.9 15.4 33.2 26.1 24.3 12.8 16.2 39.9 13.1 55.6 29.3 11.3 5.7 31.2 29.1 15.5 33.6 16.4 17.8 25.7 NDUFS1 CI-75k ENSG00000023228 "NADH:ubiquinone oxidoreductase core subunit S1" P28331 2 206114817-206159509 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 181.7;skeletal muscle: 221.6;tongue: 225.2" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064605, CAB070844" Enhanced Supported Mitochondria NA NA 48000 "Cluster 14: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "CAB070844: , HPA064605: AB_2685297" "prognostic unfavorable (3.85e-4)" "unprognostic (1.76e-1)" "unprognostic (9.22e-3)" "unprognostic (5.01e-2)" "unprognostic (8.63e-3)" "unprognostic (3.75e-1)" "unprognostic (3.72e-2)" "unprognostic (6.18e-2)" "unprognostic (2.30e-2)" "unprognostic (3.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.47e-12)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" "unprognostic (4.73e-2)" 27.1 61.6 8.3 13.3 10.8 13.2 23.8 14.9 16.1 19.5 39.7 35.3 29.9 19.3 10.8 36.2 16.3 10.5 181.7 10.7 13.7 48.0 51.8 18.3 12.6 10.1 10.1 14.6 19.2 47.2 20.2 14.4 11.7 15.8 30.0 24.4 27.7 15.6 221.6 26.6 26.1 16.4 9.2 16.8 37.1 20.8 14.2 15.6 17.9 225.2 16.9 22.4 22.4 12.5 28.3 27.6 39.2 28.6 35.8 28.9 45.4 40.4 43.4 66.0 47.6 72.0 32.1 31.7 34.8 50.8 65.5 38.5 52.9 39.2 58.2 14.6 24.9 63.5 65.1 64.9 37.0 46.2 27.5 35.3 22.5 51.9 40.4 29.6 52.3 39.3 69.8 31.1 43.6 35.2 38.5 30.7 36.5 47.2 48.6 38.3 54.7 55.1 54.7 50.7 38.1 29.8 46.7 45.1 67.1 53.3 39.8 44.2 40.1 36.2 32.0 35.8 39.1 29.8 38.4 46.9 36.3 37.5 37.8 14.1 12.9 15.7 12.4 15.2 9.6 9.6 10.8 11.8 14.7 9.0 9.6 11.1 9.2 12.5 22.5 7.8 15.9 9.5 8.3 10.8 14.9 16.1 10.7 13.7 10.1 10.1 11.7 9.2 14.2 12.5 32.4 60.9 33.0 45.1 23.8 16.2 21.7 40.8 30.1 97.1 19.3 14.0 582.5 48.6 42.8 38.6 120.9 48.4 18.8 74.5 93.9 44.2 14.5 49.8 49.8 36.6 51.0 42.0 67.8 28.2 33.7 42.3 48.4 54.5 37.3 42.3 29.3 94.5 34.0 117.8 72.8 47.9 54.9 31.2 10.7 7.0 33.5 27.7 30.2 28.1 37.2 62.7 27.8 45.2 41.6 32.1 46.4 44.8 31.0 19.9 77.8 102.3 53.5 81.5 32.9 55.2 60.8 58.2 49.5 40.8 16.6 52.5 23.7 71.5 69.9 26.6 EEF1B2 ENSG00000114942 "Eukaryotic translation elongation factor 1 beta 2" P24534 2 206159585-206162928 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012477, HPA035029" Supported Approved "Nucleoli fibrillar center,Cytosol" NA NA 840000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli fibrillar center, Cytosol" "CAB012477: AB_732078, HPA035029: AB_2674422" "prognostic favorable (2.60e-4)" "unprognostic (3.12e-1)" "unprognostic (4.22e-2)" "unprognostic (6.44e-2)" "unprognostic (4.74e-2)" "unprognostic (2.70e-1)" "unprognostic (1.49e-3)" "unprognostic (1.33e-1)" "prognostic unfavorable (9.95e-4)" "unprognostic (2.70e-1)" "unprognostic (5.37e-3)" "unprognostic (1.29e-1)" "prognostic unfavorable (3.62e-6)" "unprognostic (2.38e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-2)" 586.3 402.8 181.5 255.4 188.7 685.9 567.1 177.3 262.6 586.6 236.1 512.2 341.2 453.9 131.2 768.3 515.6 144.0 357.5 171.5 181.9 416.1 445.8 357.3 460.2 185.0 181.1 807.9 1586.9 95.6 219.8 139.5 188.0 357.5 292.3 53.0 468.0 147.5 1038.4 764.6 574.1 192.1 192.7 576.2 491.0 163.3 185.5 346.3 266.6 372.2 444.7 487.7 572.5 190.1 278.2 330.0 377.0 357.3 542.8 914.1 816.4 584.5 556.7 560.1 367.4 733.1 454.2 792.3 358.8 648.9 310.4 352.7 520.1 647.3 509.3 245.8 469.2 562.2 442.9 998.5 719.8 1189.2 483.1 932.9 755.6 418.1 939.0 545.0 605.2 629.9 782.8 644.2 628.0 568.2 946.5 916.2 552.5 628.0 565.3 731.7 796.0 1007.4 606.0 521.8 384.1 395.2 211.1 461.8 588.8 439.8 283.3 1349.0 431.1 290.9 403.6 391.7 529.1 681.5 631.0 918.3 338.7 751.5 224.1 93.9 357.8 44.1 432.5 370.9 794.4 1075.6 761.7 576.5 676.4 848.7 1075.2 897.6 47.9 609.1 298.1 650.3 448.7 1770.3 181.5 188.7 177.3 262.6 171.5 181.9 185.0 181.1 188.0 192.7 185.5 190.1 614.8 198.7 346.8 9.4 2022.8 1142.4 1787.7 737.1 1367.0 114.5 1353.8 2138.0 164.5 619.1 474.5 163.7 27.1 853.8 1097.6 591.9 688.7 756.0 187.8 284.9 1021.6 596.6 445.0 1188.1 13.0 1883.8 1657.1 597.5 575.4 403.4 547.2 1584.1 461.2 682.3 823.0 52.2 12.6 1316.9 270.6 826.2 1008.4 463.5 866.7 868.0 533.6 11.2 1049.6 193.2 924.8 6.0 15.4 890.3 990.9 483.7 1393.5 1529.4 1952.4 1222.5 228.5 117.9 269.5 615.5 748.0 153.7 287.4 2237.4 1259.6 950.5 1228.8 1381.0 1734.8 1525.9 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 ZDBF2 "FLJ45338, KIAA1571" ENSG00000204186 "Zinc finger DBF-type containing 2" Q9HCK1 2 206274663-206314427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.0;Granulosa cells: 44.4;Inhibitory neurons: 56.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SuSa: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039121, HPA050311" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Cytosol "HPA039121: AB_2676357, HPA050311: AB_2681081" "unprognostic (8.32e-2)" "unprognostic (1.66e-1)" "unprognostic (2.75e-2)" "unprognostic (2.86e-2)" "unprognostic (3.27e-2)" "unprognostic (4.52e-2)" "unprognostic (2.01e-1)" "unprognostic (2.98e-1)" "unprognostic (7.73e-3)" "unprognostic (7.59e-2)" "unprognostic (4.41e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (9.59e-2)" "unprognostic (3.08e-1)" "unprognostic (3.09e-1)" "unprognostic (1.40e-1)" 2.3 4.1 1.8 0.9 3.5 0.6 1.6 3.4 1.8 3.0 7.8 2.4 0.4 2.6 1.7 1.1 3.2 1.2 2.3 2.3 3.8 1.4 1.5 1.3 1.1 1.2 1.4 9.5 5.0 1.5 8.0 2.3 1.1 1.8 0.6 5.5 1.7 1.4 2.7 1.1 1.7 1.3 0.4 1.4 2.0 1.7 3.5 0.9 2.0 1.5 0.9 1.7 2.0 0.4 1.4 0.2 4.4 0.8 1.7 1.4 6.9 1.4 1.5 0.7 0.9 0.4 1.2 0.0 0.6 1.5 2.6 0.3 3.0 1.1 1.3 1.4 2.9 0.0 3.4 0.1 2.2 1.3 2.9 1.4 1.9 1.4 2.7 5.1 2.1 1.1 0.2 1.9 2.1 0.2 0.4 0.0 6.2 0.1 1.6 0.0 4.6 0.0 0.8 0.6 2.4 5.6 2.6 0.0 2.5 10.0 0.1 0.0 2.6 0.7 2.3 0.5 1.1 4.1 1.1 0.2 3.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 3.5 3.4 1.8 2.3 3.8 1.2 1.4 1.1 0.4 3.5 0.4 6.9 3.2 3.9 15.7 19.3 4.0 1.9 3.1 7.4 26.9 4.4 3.3 9.2 1.5 4.4 11.0 14.6 5.2 9.7 0.6 0.0 2.8 4.1 1.9 7.5 5.1 7.8 0.8 75.0 2.2 6.9 11.7 4.6 0.6 12.7 44.4 3.3 3.4 0.5 8.4 56.5 1.3 4.1 0.3 4.2 5.1 4.4 2.3 1.8 18.7 0.1 8.7 0.0 26.2 3.1 1.2 0.5 5.3 23.4 3.5 1.0 2.3 10.6 18.1 0.0 19.2 9.2 4.4 9.0 6.0 3.3 9.0 13.5 24.5 0.5 0.8 ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.7;parathyroid gland: 82.9" "Group enriched" "Detected in many" 4 "Excitatory neurons: 410.0;Inhibitory neurons: 236.6;Oligodendrocyte precursor cells: 127.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 54.4;RH-30: 63.8;RPMI-8226: 172.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033276 Approved "Secreted in brain" NA NA 890000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB033276: AB_2305247" "unprognostic (7.33e-2)" "unprognostic (7.80e-2)" "unprognostic (4.60e-1)" "unprognostic (5.77e-2)" "unprognostic (1.58e-1)" "unprognostic (3.59e-2)" "unprognostic (4.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.09e-1)" "unprognostic (6.84e-2)" "unprognostic (1.09e-2)" "unprognostic (2.64e-2)" "unprognostic (9.75e-6)" "unprognostic (3.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.16e-3)" "unprognostic (1.03e-3)" 1.7 7.5 14.3 2.4 20.6 2.0 1.1 3.5 45.7 3.2 0.0 3.0 1.5 2.2 3.8 4.0 0.8 4.2 30.7 20.6 9.6 0.9 0.3 1.5 2.1 13.9 10.2 2.0 1.2 82.9 6.4 0.2 12.9 1.7 2.2 17.4 1.5 2.4 11.1 1.1 3.2 4.5 1.6 0.8 1.6 8.0 17.4 4.9 1.0 8.7 2.7 3.0 4.1 24.0 0.1 0.9 22.3 0.0 11.9 17.2 0.9 2.4 2.9 3.2 0.6 26.8 0.5 3.3 0.0 3.8 39.5 33.9 14.5 0.7 0.3 13.2 12.4 0.0 2.1 0.3 11.4 0.3 1.4 6.5 0.1 0.1 0.0 54.4 39.4 1.2 0.0 0.1 8.2 0.4 0.3 0.0 43.9 0.4 4.6 0.1 63.8 172.6 0.0 16.6 17.4 7.0 0.0 0.0 12.9 10.9 0.1 0.0 34.3 11.1 10.2 6.0 5.3 45.2 0.1 0.0 21.1 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.3 20.6 3.5 45.7 20.6 9.6 13.9 10.2 12.9 1.6 17.4 24.0 1.6 0.0 0.0 41.8 0.4 0.4 0.9 0.1 0.6 39.3 0.0 0.1 62.8 0.0 0.0 1.8 2.1 0.0 0.1 0.0 0.0 0.0 17.6 0.3 7.7 2.7 1.8 0.0 410.0 0.0 0.0 4.3 0.0 0.2 0.0 15.0 0.0 0.1 0.0 3.3 236.6 0.0 0.0 0.0 0.3 57.7 0.6 0.1 3.6 10.3 0.0 4.1 0.0 127.2 22.3 0.1 1.1 3.0 0.0 0.5 0.0 0.0 0.7 6.8 0.0 14.2 2.2 5.1 4.7 1.5 0.4 0.1 2.0 45.2 0.0 0.1 FAM237A ENSG00000235118 "Family with sequence similarity 237 member A" A0A1B0GTK4 2 206642487-206649365 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in single" NA NA "unprognostic (3.02e-1)" 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.2 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.7 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.8 0.6 0.7 0.3 0.3 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DYTN ENSG00000232125 Dystrotelin A2CJ06 2 206651621-206721570 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7 "Erythroid cells: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 12: Non-specific - Cell cycle regulation" "unprognostic (3.23e-3)" "unprognostic (8.52e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MDH1B "FLJ25341, RP11-95H11" ENSG00000138400 "Malate dehydrogenase 1B" Q5I0G3 2 206737763-206765328 "Metabolic proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 15.7;fallopian tube: 22.5;testis: 24.5" "Cell type enhanced" "Detected in many" "Early spermatids: 186.0;Endometrial ciliated cells: 50.1;Late spermatids: 33.7;Respiratory ciliated cells: 100.5;Spermatocytes: 114.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 3.6;SCLC-21H: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA073761 Approved NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA073761: AB_2732241" "unprognostic (1.03e-2)" "unprognostic (9.44e-2)" "unprognostic (1.58e-1)" "unprognostic (9.84e-2)" "unprognostic (1.54e-1)" "unprognostic (6.31e-2)" "unprognostic (2.55e-2)" "unprognostic (8.21e-2)" "unprognostic (2.01e-1)" "unprognostic (3.66e-2)" "unprognostic (3.23e-3)" "unprognostic (3.08e-1)" "unprognostic (6.10e-3)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (7.84e-3)" "unprognostic (3.01e-1)" 0.4 1.5 2.2 0.2 2.5 0.1 1.2 1.9 2.4 1.7 15.7 1.2 0.0 1.7 1.7 0.5 22.5 0.8 1.3 2.4 2.8 3.1 0.3 2.0 0.3 4.2 5.3 1.0 0.9 4.2 9.3 0.0 3.9 0.9 0.5 8.5 1.0 1.3 0.4 0.4 0.3 0.8 3.5 0.2 0.7 24.5 2.8 0.5 4.8 0.5 0.2 0.5 0.4 3.0 0.3 1.2 0.9 2.5 0.1 1.1 0.3 0.0 0.4 0.5 0.3 0.1 0.8 0.5 0.5 0.1 1.1 0.6 0.0 0.7 0.5 0.0 0.0 0.2 0.2 0.8 0.5 0.4 1.2 0.7 0.2 0.0 0.1 0.5 0.7 1.1 0.0 0.7 0.3 1.5 0.8 0.3 1.6 0.1 1.4 1.6 0.9 0.0 3.6 0.2 3.5 0.7 1.1 0.5 0.3 0.5 1.1 0.0 0.0 0.6 0.6 0.1 0.3 0.3 1.6 0.2 1.3 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.5 1.9 2.4 2.4 2.8 4.2 5.3 3.9 3.5 2.8 3.0 0.2 6.4 1.5 6.8 0.0 0.8 1.4 3.9 1.8 3.0 2.1 2.4 1.3 2.8 6.4 0.0 0.0 0.1 0.0 0.0 13.7 1.3 186.0 50.1 1.2 0.6 1.2 0.0 8.9 0.0 0.1 1.3 1.5 1.6 0.0 1.1 0.0 0.0 0.1 3.3 6.3 0.0 10.2 0.0 0.2 33.7 1.8 0.5 1.8 1.9 0.0 9.6 0.0 1.0 1.3 0.1 0.0 3.0 0.0 0.4 0.0 6.0 100.5 10.2 0.0 0.5 1.7 114.9 5.1 0.5 0.3 0.0 0.2 1.6 0.1 0.9 FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067191 Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA067191: AB_2685801" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "unprognostic (3.50e-3)" "unprognostic (1.36e-3)" "unprognostic (7.40e-2)" "unprognostic (2.69e-3)" "prognostic unfavorable (8.29e-4)" "unprognostic (1.69e-2)" "unprognostic (2.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.38e-3)" "unprognostic (1.48e-1)" "unprognostic (6.32e-2)" "unprognostic (4.87e-2)" "unprognostic (7.18e-2)" "unprognostic (1.03e-3)" "unprognostic (3.57e-2)" 14.4 14.0 5.2 12.4 5.9 11.4 17.3 4.8 6.2 12.8 7.5 15.0 14.9 15.8 8.8 15.9 12.9 11.5 24.9 5.7 5.3 17.4 27.2 11.8 14.3 5.8 4.5 15.7 11.6 18.4 6.9 13.0 6.5 13.3 17.0 11.2 11.2 11.1 31.5 11.8 12.5 15.7 4.4 11.2 13.3 12.0 4.9 13.1 17.8 36.6 17.2 20.4 9.6 4.8 30.2 27.0 24.7 28.1 27.2 32.7 46.2 34.3 29.0 57.3 32.4 48.3 32.0 37.4 37.5 35.5 66.7 40.0 30.7 47.4 50.4 11.7 19.8 29.4 25.6 46.6 33.1 64.3 26.5 35.2 48.8 43.8 47.2 29.1 39.3 27.2 56.4 18.6 42.8 25.3 27.3 27.4 44.0 28.2 51.2 23.7 38.1 38.8 39.4 49.7 36.0 22.9 26.6 44.7 41.3 36.8 20.9 33.4 30.8 35.0 31.5 24.4 36.3 18.5 32.9 48.0 40.6 29.2 29.5 9.6 21.4 5.2 19.2 21.4 21.5 20.1 21.3 20.2 31.0 17.3 28.0 25.2 1.4 31.2 16.5 14.6 18.7 20.5 5.2 5.9 4.8 6.2 5.7 5.3 5.8 4.5 6.5 4.4 4.9 4.8 17.8 28.9 11.4 19.6 20.3 23.7 33.7 28.8 32.5 18.9 11.1 12.2 23.2 7.2 22.8 12.9 22.9 28.2 15.1 6.7 9.8 19.2 30.9 14.5 23.1 14.6 7.3 11.6 41.9 15.1 22.4 21.2 27.5 14.9 5.1 17.5 9.3 17.6 14.8 6.7 40.3 10.5 12.2 7.9 9.4 8.0 9.6 10.8 5.4 25.3 12.9 9.3 8.2 26.2 23.2 12.1 8.2 13.9 20.0 13.7 8.8 12.7 15.9 22.8 13.1 19.3 17.4 37.5 12.8 24.5 21.5 25.7 18.4 18.6 13.1 22.6 CPO ENSG00000144410 "Carboxypeptidase O" Q8IVL8 2 206939518-206969474 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 111.8" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 349.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 12.0" "Lineage enriched" "Detected in single" 84 "granulocytes: 12.0" "Cell line enhanced" "Detected in single" "NB-4: 1.0" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "unprognostic (9.39e-2)" "unprognostic (2.64e-1)" "unprognostic (2.95e-2)" "unprognostic (5.21e-2)" "unprognostic (2.28e-1)" "unprognostic (1.27e-2)" "unprognostic (1.16e-1)" "unprognostic (9.06e-2)" "unprognostic (4.03e-1)" "unprognostic (1.33e-1)" "unprognostic (3.75e-3)" "unprognostic (1.22e-1)" "unprognostic (3.60e-2)" "unprognostic (2.52e-1)" "unprognostic (6.56e-2)" "unprognostic (4.03e-2)" "unprognostic (4.89e-2)" 0.7 1.0 2.4 0.1 2.4 0.0 0.8 1.3 3.1 0.5 1.2 1.2 0.5 0.3 7.5 0.2 0.7 0.4 0.4 2.2 2.3 1.3 0.7 0.3 0.1 2.0 2.1 0.4 0.5 1.0 1.2 0.2 2.3 0.9 0.4 0.6 0.8 0.8 0.7 0.5 111.8 0.7 2.1 0.2 0.5 0.8 2.4 0.1 1.0 0.5 0.1 0.5 0.3 3.3 0.0 0.0 0.0 0.0 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 12.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 2.4 1.3 3.1 2.2 2.3 2.0 2.1 2.3 2.1 2.4 3.3 0.1 0.0 0.0 9.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.2 0.0 0.0 0.0 43.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 35.9 6.3 0.0 0.0 0.0 0.7 0.3 0.0 0.0 6.5 0.0 0.0 0.0 2.0 14.6 0.0 3.8 0.0 0.0 0.0 349.9 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 KLF7 UKLF ENSG00000118263 "Kruppel like factor 7" O75840 2 207074137-207167267 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 95.2;Oligodendrocytes: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003423, HPA030490" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Nucleoplasm Cytosol "HPA003423: , HPA030490: AB_10601922" "unprognostic (5.93e-2)" "unprognostic (2.49e-3)" "unprognostic (2.98e-1)" "unprognostic (3.99e-3)" "unprognostic (2.56e-1)" "unprognostic (2.85e-3)" "unprognostic (5.44e-2)" "unprognostic (1.24e-2)" "unprognostic (6.75e-2)" "unprognostic (8.78e-2)" "unprognostic (3.67e-2)" "unprognostic (1.47e-1)" "prognostic favorable (4.26e-4)" "unprognostic (3.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (3.47e-2)" 19.9 8.2 8.2 13.8 15.0 40.3 15.0 19.3 9.1 8.9 0.0 11.4 4.6 16.9 5.9 9.7 10.0 11.8 10.1 8.3 13.4 7.9 7.1 15.2 7.7 20.2 17.0 14.2 5.1 3.0 4.9 5.8 20.9 8.2 5.3 4.7 7.4 7.4 4.9 6.8 10.3 20.9 12.1 10.3 9.1 6.8 17.4 14.3 8.8 7.4 7.3 9.8 9.8 20.3 8.8 6.1 16.3 1.1 5.6 14.4 3.4 10.0 8.0 15.3 6.7 0.1 7.1 0.1 6.3 20.6 26.5 21.5 13.9 46.2 8.2 6.0 0.8 0.2 18.5 3.5 9.7 4.6 6.7 19.3 15.3 10.7 35.0 22.0 18.1 4.6 0.0 8.2 11.8 0.2 5.6 1.7 9.7 0.9 3.0 2.4 4.3 6.4 3.7 6.8 25.0 30.5 8.6 12.0 7.8 13.0 2.0 6.9 35.9 30.3 14.5 12.9 12.0 6.2 4.5 0.0 26.7 3.8 6.1 28.9 9.4 12.3 1.6 12.1 0.6 5.7 8.4 1.6 5.3 7.7 14.3 9.9 40.8 22.9 22.7 2.4 7.7 6.1 8.2 15.0 19.3 9.1 8.3 13.4 20.2 17.0 20.9 12.1 17.4 20.3 95.2 41.7 6.7 74.4 15.8 21.9 23.1 35.0 6.2 9.0 9.9 11.4 17.6 14.3 15.1 9.2 12.5 0.5 6.9 0.4 1.9 22.7 10.2 13.9 33.7 65.8 6.0 2.5 46.4 51.5 0.8 22.0 11.7 17.3 12.0 3.6 79.9 14.7 15.6 11.8 31.1 2.6 34.6 50.0 22.9 5.2 13.7 37.6 3.6 61.8 28.3 7.1 8.2 68.9 160.5 79.9 1.4 10.1 4.3 9.2 14.1 4.3 9.8 8.7 46.0 38.6 42.0 0.8 14.8 8.1 15.3 1.1 7.6 7.9 4.3 9.3 CREB1 ENSG00000118260 "CAMP responsive element binding protein 1" P16220 2 207529737-207605988 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Early spermatids: 417.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003803, HPA019150" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "CAB003803: AB_562092, HPA019150: AB_1847220" "unprognostic (1.20e-1)" "unprognostic (3.15e-1)" "unprognostic (3.30e-2)" "unprognostic (2.69e-2)" "unprognostic (3.16e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (8.41e-2)" "unprognostic (1.04e-2)" "unprognostic (2.53e-1)" "unprognostic (9.58e-2)" "unprognostic (1.74e-2)" "unprognostic (4.82e-3)" "unprognostic (5.53e-3)" "unprognostic (1.06e-1)" "unprognostic (1.77e-1)" "unprognostic (8.45e-2)" 13.0 8.7 10.6 15.3 11.4 22.4 14.7 17.5 11.1 15.8 11.9 11.4 10.0 15.7 10.8 15.0 13.1 14.0 11.5 10.3 10.7 12.4 11.6 13.6 22.1 10.6 9.9 17.2 8.7 15.6 6.9 18.0 10.4 13.0 14.0 17.8 8.9 12.6 6.7 11.5 10.6 16.3 9.7 17.1 12.1 32.4 9.9 28.7 18.1 14.6 25.0 16.8 9.6 15.0 24.9 20.9 38.6 15.6 22.9 22.4 21.8 15.9 23.5 26.6 26.5 21.6 22.9 15.4 19.8 21.1 29.8 19.5 34.8 20.4 37.7 25.1 13.2 29.2 18.9 23.0 18.7 27.7 20.0 16.0 16.3 21.1 31.1 25.4 34.9 28.9 20.5 22.5 30.4 16.8 41.0 16.1 27.8 24.2 13.1 31.4 22.1 20.2 25.1 24.6 27.1 23.4 21.6 16.2 18.1 35.5 16.5 30.1 18.5 21.8 22.6 22.1 20.5 19.6 27.5 36.4 25.2 25.3 22.0 33.6 28.2 28.2 27.0 29.2 23.7 36.7 25.3 26.2 34.1 34.8 30.0 20.7 56.1 45.6 34.9 18.6 38.6 26.7 10.6 11.4 17.5 11.1 10.3 10.7 10.6 9.9 10.4 9.7 9.9 15.0 46.7 19.2 18.2 47.0 52.3 70.9 47.1 33.3 34.1 38.9 25.3 18.5 26.3 17.2 29.0 12.9 33.3 29.1 35.5 25.3 23.5 23.6 417.8 19.6 39.2 47.2 32.4 54.7 56.1 20.3 24.9 35.8 18.8 21.0 43.7 41.5 35.7 15.8 29.4 40.4 51.1 28.2 30.5 48.8 75.9 47.2 26.1 35.8 44.4 68.4 60.9 42.1 33.0 66.9 70.7 26.4 27.5 29.3 29.1 56.5 22.8 19.7 18.9 40.2 39.5 37.4 40.7 44.5 29.4 33.5 57.8 18.6 42.6 19.6 25.7 62.6 METTL21A "FAM119A, HCA557b, HSPA-KMT, LOC151194" ENSG00000144401 "Methyltransferase like 21A" Q8WXB1 2 207580631-207625928 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Paneth cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "HPA034712: AB_10670160" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (4.56e-2)" "unprognostic (2.09e-3)" "unprognostic (2.00e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (4.80e-2)" "unprognostic (2.30e-2)" "unprognostic (2.47e-3)" "unprognostic (6.65e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (5.43e-4)" "unprognostic (5.01e-2)" "unprognostic (3.05e-1)" "unprognostic (1.52e-2)" "unprognostic (2.05e-1)" 11.1 9.0 18.9 10.8 20.3 22.7 7.9 24.8 24.6 8.9 14.7 9.4 8.2 9.7 7.9 6.7 7.9 7.0 13.7 17.7 19.9 11.2 23.7 9.0 16.5 20.1 19.2 11.1 8.8 9.9 9.9 12.5 20.1 8.4 8.9 16.0 8.6 6.5 21.9 9.2 8.8 7.6 15.1 16.2 12.1 7.6 21.6 17.6 12.4 8.8 15.0 8.5 6.8 27.6 18.4 16.8 27.4 20.8 11.9 12.4 53.0 10.1 12.3 15.9 16.0 32.3 28.6 26.2 21.5 7.7 27.8 10.4 39.6 13.2 13.1 15.3 27.1 30.9 26.7 53.6 21.0 40.7 30.0 11.1 17.2 7.9 13.2 19.5 18.1 43.3 45.0 15.1 10.6 29.7 41.2 69.4 45.5 24.9 11.8 30.1 11.4 38.2 23.0 15.3 32.3 26.5 21.8 7.4 21.6 37.8 10.3 59.4 9.3 13.8 30.6 12.9 17.8 22.3 29.8 54.1 22.6 31.5 20.9 32.8 28.6 54.8 9.5 29.0 16.0 54.2 14.4 13.7 24.1 44.8 26.8 17.4 10.4 16.9 45.6 30.0 12.7 16.6 18.9 20.3 24.8 24.6 17.7 19.9 20.1 19.2 20.1 15.1 21.6 27.6 30.8 16.0 25.3 16.0 55.0 15.9 38.1 25.7 5.7 22.0 16.6 16.4 23.8 21.5 23.1 11.0 8.4 35.5 24.3 17.1 29.4 27.9 31.4 12.5 10.1 24.6 5.4 42.5 20.6 25.1 31.3 16.9 18.3 8.5 46.3 17.7 20.7 12.3 29.9 18.5 17.6 16.3 69.2 22.2 93.7 45.6 9.9 32.8 44.4 44.0 29.7 17.4 16.5 20.6 25.9 23.8 114.4 7.5 16.6 48.1 8.9 23.4 23.3 20.3 13.1 9.6 16.0 24.8 19.1 9.3 12.6 10.5 23.0 15.6 18.6 19.6 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 23.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.4;Hepatocytes: 59.8;Intestinal goblet cells: 50.1;Muller glia cells: 50.7;Undifferentiated cells: 57.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 104.7;CACO-2: 26.2;Hep G2: 36.5;NTERA-2: 31.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" 6.0 5.0 1.8 2.5 3.5 4.2 2.4 1.8 3.6 3.0 3.5 18.3 18.6 2.3 0.6 3.3 1.2 1.4 1.6 1.7 3.6 5.1 23.5 6.7 1.1 3.2 4.9 4.2 10.4 1.0 4.7 4.4 2.5 6.3 14.7 10.9 3.1 2.7 2.6 1.0 15.3 2.6 1.8 2.0 11.2 0.4 2.7 1.5 8.7 2.0 1.4 1.7 2.3 6.2 3.3 5.8 0.3 3.1 2.6 0.1 104.7 0.5 0.7 0.8 0.7 26.2 6.0 0.6 7.0 0.3 2.0 4.8 9.0 3.9 0.7 0.4 6.9 7.6 2.8 36.5 2.0 1.5 2.0 0.2 3.7 1.2 3.0 2.0 1.0 1.1 15.5 1.2 0.7 2.3 0.8 1.9 31.0 14.2 2.0 1.9 3.3 1.4 7.3 11.4 5.0 0.7 1.4 0.6 1.5 14.1 1.7 1.5 0.4 1.6 3.0 3.2 2.5 1.7 4.1 1.3 2.1 1.7 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.5 1.8 3.6 1.7 3.6 3.2 4.9 2.5 1.8 2.7 6.2 6.5 32.1 32.6 4.6 2.0 5.1 5.4 5.4 6.2 2.2 8.7 3.7 7.8 25.8 4.8 1.8 33.3 18.9 1.6 117.4 0.0 14.9 0.7 9.0 2.2 4.1 12.6 15.1 0.5 24.7 6.0 3.2 17.3 18.8 0.0 16.8 2.9 59.8 10.5 6.7 0.9 50.1 6.1 8.4 9.8 0.1 1.8 3.3 1.8 1.0 0.7 50.7 0.0 0.0 6.0 18.2 38.6 0.4 0.5 12.5 43.2 12.2 3.4 7.0 0.0 8.1 4.5 1.5 2.1 4.0 4.1 4.0 1.4 8.1 57.6 5.9 PLEKHM3 "DAPR, PLEKHM1L" ENSG00000178385 "Pleckstrin homology domain containing M3" Q6ZWE6 2 207821288-208025527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 99.1;Inhibitory neurons: 70.5;Microglial cells: 36.5;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035046 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "HPA035046: AB_10603128" "unprognostic (3.62e-1)" "unprognostic (1.58e-2)" "unprognostic (8.27e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (4.77e-2)" "unprognostic (6.06e-2)" "unprognostic (8.20e-2)" "unprognostic (4.13e-2)" "unprognostic (2.92e-3)" "unprognostic (2.17e-1)" "unprognostic (1.09e-1)" "unprognostic (4.86e-4)" "unprognostic (2.42e-1)" "unprognostic (3.12e-1)" "unprognostic (5.72e-2)" "unprognostic (1.33e-2)" 2.9 4.1 2.3 1.3 2.6 4.3 2.4 0.4 2.9 2.7 0.0 3.1 0.9 2.5 0.9 1.6 2.0 1.4 2.9 2.8 2.1 1.9 3.1 2.9 1.5 2.0 2.6 3.1 2.2 4.0 2.5 1.4 2.2 2.5 1.5 8.3 2.2 1.4 2.4 2.6 1.9 1.9 0.2 1.9 2.2 1.7 1.3 2.2 3.6 1.6 1.4 1.9 2.5 2.0 0.7 0.7 1.6 0.9 2.7 2.7 2.5 1.5 1.6 1.2 1.1 0.9 0.7 0.6 1.5 1.8 1.2 0.8 1.7 2.2 1.6 1.2 2.6 1.3 2.2 1.3 1.6 1.4 0.7 2.2 2.6 1.3 1.6 1.9 1.3 2.1 0.8 1.7 1.5 0.4 1.7 0.9 1.6 0.5 0.8 1.3 1.4 1.3 0.6 0.9 3.5 1.8 1.4 0.1 1.5 2.7 0.4 1.1 1.8 1.9 1.1 1.1 1.0 2.0 2.4 0.6 2.2 0.8 1.4 1.3 0.8 0.4 0.9 0.3 0.3 0.9 0.8 0.8 0.7 0.6 1.0 0.8 2.6 0.9 0.7 0.7 0.5 0.2 2.3 2.6 0.4 2.9 2.8 2.1 2.0 2.6 2.2 0.2 1.3 2.0 6.3 19.2 21.7 29.0 2.7 0.0 0.2 0.1 0.6 3.1 4.1 3.7 1.2 1.5 5.6 1.8 12.5 0.3 4.1 1.2 0.0 3.1 2.5 4.1 6.3 2.3 0.0 4.0 99.1 3.4 0.5 3.0 2.0 4.7 0.0 25.0 0.4 0.6 0.6 6.7 70.5 0.1 0.0 1.0 2.4 5.2 0.3 3.8 0.0 36.5 4.6 2.3 0.0 45.2 86.9 3.5 1.6 0.0 2.0 0.2 1.1 4.9 0.8 9.6 0.0 1.7 3.8 0.4 0.7 1.1 0.1 0.1 2.5 6.9 0.5 0.1 CRYGD CRYG4 ENSG00000118231 "Crystallin gamma D" P07320 2 208121607-208124524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "ovary: 8.0" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 140.2" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 20 "HEL: 10.0" "Not detected" "Not detected" "HPA041269, HPA043386" Supported Approved Vesicles,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA041269: AB_2732491, HPA043386: " "unprognostic (4.49e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.5 0.0 0.4 1.3 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.5 0.7 8.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.8 0.5 0.6 0.5 0.7 0.6 0.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.1 0.0 4.6 0.3 0.0 0.1 0.9 0.0 0.0 0.0 140.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 34.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.9 0.1 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CRYGC CRYG3 ENSG00000163254 "Crystallin gamma C" P07315 2 208128137-208129828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.7" "Group enriched" "Detected in some" 13 "Early spermatids: 1.9;Granulosa cells: 3.7;Late spermatids: 3.2;Spermatocytes: 2.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8;ovarian cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "hippocampal formation: 3.2;hypothalamus: 1.5;thalamus: 1.2" "Group enriched" "Detected in some" 14 "cerebral cortex: 1.2;hippocampal formation: 1.5" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRYGB CRYG2 ENSG00000182187 "Crystallin gamma B" P07316 2 208142573-208146158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.1" "Group enriched" "Detected in some" 6 "ovarian cancer: 1.1;testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "hippocampal formation: 3.3;hypothalamus: 2.2;thalamus: 2.0" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA043386: " "unprognostic (6.73e-2)" "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRYGA "CRY-g-A, CRYG1, CRYG5" ENSG00000168582 "Crystallin gamma A" P11844 2 208160740-208163589 "Predicted intracellular proteins" "Eye lens protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Oligodendrocyte precursor cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043386 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.49e-1)" 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.7 0.6 0.3 0.2 0.3 0.2 0.3 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf80 "GONDA1, LOC389073" ENSG00000188674 "Chromosome 2 open reading frame 80" Q0P641 2 208165343-208190030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "brain: 31.8" "Group enriched" "Detected in some" 8 "Excitatory neurons: 25.8;Inhibitory neurons: 11.7;Oligodendrocyte precursor cells: 31.7" "Cancer enriched" "Detected in single" 41 "glioma: 11.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 3.2;neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Cell line enhanced" "Detected in single" "NTERA-2: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042639 Approved "Golgi apparatus" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "HPA042639: AB_10794915" "unprognostic (6.36e-2)" "unprognostic (2.12e-1)" "unprognostic (2.95e-1)" "unprognostic (3.05e-1)" "unprognostic (1.83e-1)" "unprognostic (2.98e-2)" 0.0 0.1 21.0 0.4 26.5 1.1 0.0 6.3 31.8 0.0 7.4 0.2 0.2 0.1 0.0 0.9 0.1 0.2 0.1 27.2 20.5 0.1 0.3 0.0 0.2 11.6 13.3 0.2 0.0 0.1 1.0 0.1 13.9 0.2 0.2 1.4 0.3 0.4 0.3 0.4 0.3 0.1 11.0 0.1 0.2 0.6 17.0 0.0 0.1 0.0 0.0 0.0 0.0 15.1 0.1 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.4 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.3 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.5 1.7 0.1 0.5 0.1 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.3 3.2 0.6 0.5 0.3 0.4 0.2 0.5 0.3 0.3 0.2 0.7 0.3 0.3 4.6 0.5 0.3 0.8 0.1 0.1 21.0 26.5 6.3 31.8 27.2 20.5 11.6 13.3 13.9 11.0 17.0 15.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 11.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 2.8 0.0 1.0 0.0 31.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 536.3" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 320.2;Granulosa cells: 257.5;Hepatocytes: 328.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 768.1;RT4: 524.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 16000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies, Cytosol" "CAB033218: AB_2123166, CAB062556: AB_2665593, HPA035248: AB_10600714, HPA057936: AB_2683559" "unprognostic (2.79e-1)" "unprognostic (1.00e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-3)" "unprognostic (1.93e-1)" "unprognostic (2.39e-2)" "prognostic unfavorable (6.93e-5)" "unprognostic (3.32e-1)" "unprognostic (2.20e-3)" "unprognostic (8.03e-2)" "unprognostic (5.54e-2)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.45e-5)" "unprognostic (2.09e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" 150.8 230.8 24.0 37.5 23.9 10.7 63.0 24.6 30.9 67.9 40.8 124.9 179.4 22.9 164.9 92.2 36.6 69.5 25.3 23.5 26.1 122.0 536.3 49.8 33.3 26.4 25.7 84.4 39.9 42.0 16.7 82.5 25.9 214.6 131.2 35.0 59.3 79.1 25.7 23.6 117.4 43.8 25.5 40.1 113.6 57.0 30.0 21.8 45.5 28.1 29.8 153.1 39.9 30.6 66.5 109.6 152.5 63.3 275.1 191.4 86.7 26.3 122.3 44.2 107.3 176.1 159.1 13.1 168.8 84.4 181.6 101.4 112.4 130.7 43.0 8.8 41.7 56.7 87.3 768.1 367.3 37.0 54.7 169.5 278.0 102.7 74.2 69.8 126.1 37.2 58.1 44.5 68.9 42.8 26.3 66.2 284.5 479.7 43.9 25.2 54.8 37.8 206.3 524.0 25.9 45.2 100.5 99.7 351.7 161.2 37.9 111.0 81.1 45.2 44.1 65.3 29.6 20.8 34.5 16.9 148.2 226.7 37.0 12.4 70.1 11.0 9.1 32.3 10.6 10.6 8.2 10.9 50.9 10.1 6.7 7.8 13.8 17.2 15.5 18.8 15.1 29.9 24.0 23.9 24.6 30.9 23.5 26.1 26.4 25.7 25.9 25.5 30.0 30.6 13.9 12.8 49.5 39.2 20.2 12.4 18.8 60.5 52.3 19.5 61.8 31.5 21.8 45.8 69.1 29.5 25.0 320.2 23.7 106.8 21.5 31.1 13.8 31.0 23.4 22.0 58.4 30.3 16.6 86.5 178.8 29.6 76.0 108.8 14.0 257.5 39.7 328.2 175.3 11.8 16.2 98.4 57.0 130.2 23.8 11.2 24.5 71.7 26.6 19.7 47.8 25.4 18.6 66.4 20.0 44.8 55.5 29.3 13.7 53.2 181.2 108.5 21.9 56.6 13.1 7.8 23.6 8.0 26.2 82.4 14.9 95.6 19.8 127.1 129.3 46.7 PIKFYVE "FAB1, KIAA0981, MGC40423, p235, PIP5K, PIP5K3, ZFYVE29" ENSG00000115020 "Phosphoinositide kinase, FYVE-type zinc finger containing" Q9Y2I7 2 208266255-208358746 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 82.0;Oligodendrocyte precursor cells: 80.9;Oligodendrocytes: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042604 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA042604: AB_10796580" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.88e-1)" "unprognostic (3.03e-1)" "unprognostic (2.04e-2)" "prognostic favorable (6.81e-4)" "unprognostic (6.82e-3)" "unprognostic (6.45e-2)" "unprognostic (1.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" 10.4 7.9 7.6 12.0 7.6 28.8 8.1 14.3 9.3 9.1 10.5 6.1 6.0 9.3 11.9 6.3 6.4 7.2 7.4 7.7 7.3 10.6 10.5 7.8 17.4 8.0 7.4 10.0 22.2 11.1 6.0 9.7 6.9 11.5 7.4 17.3 6.5 8.0 6.5 8.2 7.3 8.9 7.4 15.1 8.0 14.0 8.9 19.3 12.2 9.0 16.1 8.2 5.8 11.1 8.0 7.9 18.3 14.3 18.1 21.4 8.5 9.6 19.5 11.1 15.0 11.3 6.6 9.2 9.8 16.6 21.7 8.0 16.1 10.8 18.8 7.9 10.1 33.0 15.6 10.2 13.7 29.5 28.5 16.0 11.5 13.0 24.1 18.5 18.3 24.1 22.7 16.1 14.0 3.4 26.9 22.1 15.2 6.1 5.9 9.9 14.2 12.7 14.2 11.5 5.8 13.8 10.6 6.8 19.2 21.4 4.3 31.3 21.2 13.8 9.2 9.4 9.0 11.2 14.2 19.2 11.1 25.2 13.9 0.9 0.5 0.4 0.9 0.4 0.5 4.4 1.2 1.4 0.5 3.2 0.9 1.1 0.7 3.2 0.7 1.2 0.9 0.3 7.6 7.6 14.3 9.3 7.7 7.3 8.0 7.4 6.9 7.4 8.9 11.1 18.8 25.6 16.2 58.8 82.0 15.3 6.7 7.8 25.6 21.9 10.5 6.6 17.5 11.5 10.6 11.0 16.7 8.1 14.4 8.1 5.9 5.4 10.4 11.3 19.4 18.8 18.6 25.5 72.6 4.3 5.7 15.7 16.3 21.7 36.1 18.0 18.2 19.4 14.4 10.1 67.9 9.6 4.1 29.9 32.5 8.3 18.6 28.5 10.6 48.7 19.1 13.5 16.5 80.9 81.7 8.5 5.9 13.5 10.3 18.1 14.3 9.9 9.2 19.7 13.1 15.4 18.9 30.5 23.0 14.8 15.3 7.3 21.5 13.3 8.8 11.4 PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 16.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 12.5;Distal tubular cells: 7.9;Excitatory neurons: 15.9;Proximal tubular cells: 16.1;Rod photoreceptor cells: 26.5" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "EFO-21: 10.7;HEL: 16.0;HL-60: 4.0;SH-SY5Y: 6.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" 1.2 0.3 2.2 0.1 1.1 4.2 0.9 0.0 3.1 0.0 0.1 0.0 0.0 0.7 2.1 0.0 0.0 0.0 0.0 2.4 2.0 0.2 0.6 0.1 0.1 0.3 0.6 0.0 0.6 0.0 0.3 1.2 0.2 0.5 0.0 16.5 3.6 0.5 0.0 0.1 0.0 0.5 0.1 0.1 0.0 0.5 4.5 0.0 0.0 0.0 0.1 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 2.2 1.1 0.0 3.1 2.4 2.0 0.3 0.6 0.2 0.1 4.5 1.5 0.1 0.0 0.0 0.3 0.6 0.0 0.0 0.1 0.0 1.1 1.8 3.2 0.2 0.0 0.1 5.5 12.5 0.5 0.9 0.0 7.9 0.1 0.6 0.2 0.5 0.1 1.8 4.2 15.9 0.0 0.1 0.8 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 1.0 0.1 2.5 2.1 2.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 26.5 0.0 0.0 0.4 0.6 0.4 0.0 0.0 0.1 0.1 0.3 0.0 0.0 MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424058-209734118 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 253.3;retina: 411.0" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 875.7;Excitatory neurons: 883.3;Inhibitory neurons: 823.6;Oligodendrocyte precursor cells: 688.6;Rod photoreceptor cells: 514.5" "Group enriched" "Detected in many" 4 "glioma: 30.4;thyroid cancer: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 296.9;NTERA-2: 106.7;SCLC-21H: 148.6;SH-SY5Y: 82.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001984, HPA008273, HPA012558, HPA012828" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "CAB001984: , HPA008273: AB_1853945, HPA012558: , HPA012828: AB_1853946" "unprognostic (2.47e-2)" "unprognostic (2.81e-1)" "unprognostic (2.58e-2)" "prognostic unfavorable (1.98e-6)" "unprognostic (2.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (6.06e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (7.28e-2)" "unprognostic (4.10e-5)" 5.5 11.6 89.2 1.2 115.9 0.3 5.5 2.7 253.3 4.3 0.0 2.9 0.9 2.3 3.9 6.5 2.5 7.6 8.4 135.2 215.6 5.4 3.8 13.5 1.8 37.7 52.2 7.4 10.7 15.5 33.8 0.8 75.3 7.6 1.7 411.0 7.8 4.9 1.7 16.9 1.6 2.8 14.5 1.7 3.3 6.5 123.9 3.5 16.7 4.6 2.4 1.6 5.3 88.2 2.6 0.6 296.9 0.0 3.9 2.2 0.1 1.9 2.1 0.7 2.2 0.0 16.1 0.0 1.7 3.8 14.0 4.1 23.4 1.8 1.0 0.1 1.4 1.2 8.9 0.1 36.7 0.3 0.2 3.1 9.6 0.1 5.8 17.3 7.8 0.1 0.0 3.1 0.3 1.1 0.1 0.0 106.7 0.5 0.5 0.0 0.6 0.3 3.8 0.1 148.6 82.7 6.3 0.9 3.7 34.8 8.2 0.0 0.2 0.3 1.7 0.1 4.1 1.9 0.0 0.0 15.5 0.0 45.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 89.2 115.9 2.7 253.3 135.2 215.6 37.7 52.2 75.3 14.5 123.9 88.2 16.8 96.1 3.2 127.3 1.8 5.9 3.3 12.0 4.6 144.7 6.2 8.0 4.9 27.1 3.7 5.5 875.7 0.4 0.1 0.0 3.9 26.8 22.1 2.2 1.1 15.7 32.4 2.7 883.3 11.0 0.1 5.3 3.6 4.4 1.3 1.6 18.5 0.4 0.5 33.7 823.6 0.2 6.1 1.4 1.5 10.7 28.6 1.4 19.6 74.0 0.0 129.7 0.0 688.6 53.8 10.0 0.0 15.4 0.1 12.3 0.0 0.4 3.4 514.5 32.9 5.1 26.1 6.6 22.7 2.3 6.5 0.3 0.3 6.6 0.0 0.7 UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 13.6;retina: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 117.7;Excitatory neurons: 432.0;Inhibitory neurons: 354.7;Oligodendrocyte precursor cells: 290.5" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 2.5;SCLC-21H: 4.0;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" Vesicles "HPA042472: AB_10965318, HPA050959: " "unprognostic (7.91e-3)" "unprognostic (2.25e-4)" "unprognostic (1.44e-2)" "unprognostic (3.20e-4)" "unprognostic (1.92e-1)" "unprognostic (3.40e-2)" "unprognostic (3.31e-3)" "unprognostic (5.36e-2)" "unprognostic (5.16e-1)" "unprognostic (7.85e-2)" "unprognostic (5.24e-3)" "unprognostic (8.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.51e-2)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" "unprognostic (7.40e-3)" 0.0 3.9 6.4 0.0 9.9 0.0 0.0 15.6 21.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.4 1.1 0.0 6.9 4.9 0.1 0.0 0.1 0.0 6.7 1.5 0.5 1.0 0.2 13.6 0.0 5.8 0.9 0.1 18.9 0.1 0.2 0.0 0.1 0.1 0.2 1.1 0.2 0.4 3.5 2.6 0.1 0.3 0.0 0.0 0.2 0.0 5.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 4.0 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 9.9 15.6 21.0 6.9 4.9 6.7 1.5 5.8 1.1 2.6 5.0 0.2 0.0 1.1 49.0 0.0 0.8 0.3 1.9 0.0 117.7 0.2 0.1 2.1 0.0 0.7 0.0 66.7 0.0 0.0 0.0 0.0 0.0 31.9 1.1 1.7 0.5 0.0 0.0 432.0 0.0 0.0 1.1 0.0 0.1 1.3 0.6 0.0 0.0 0.1 52.2 354.7 0.0 0.0 0.0 0.0 10.5 0.9 0.3 0.0 10.3 0.0 26.6 0.0 290.5 12.8 0.1 0.0 1.9 0.0 1.2 0.0 0.2 0.8 75.6 0.0 0.2 0.1 7.5 3.8 0.0 0.1 0.0 0.0 15.1 0.0 0.3 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 21.9 27.6 15.9 20.1 20.0 19.4 25.4 18.3 21.7 19.7 11.9 24.0 21.8 22.6 22.3 29.1 21.0 19.8 14.5 16.2 14.7 30.0 27.4 17.9 25.1 11.0 13.3 25.4 15.1 21.0 17.2 29.4 12.8 22.5 31.8 17.8 20.6 31.1 11.0 19.7 19.8 29.3 14.6 19.2 24.2 15.3 16.5 22.9 29.5 27.4 29.4 27.4 17.4 23.1 62.4 81.0 47.5 47.9 71.3 68.0 85.4 80.2 60.9 67.9 93.1 118.7 92.1 39.9 50.6 58.8 104.1 59.9 69.7 81.9 103.3 49.7 47.8 78.2 112.3 112.3 98.8 80.7 56.1 51.7 75.4 83.2 107.5 60.2 94.8 39.1 79.7 57.2 55.5 106.7 43.5 63.5 68.2 121.4 59.8 52.4 58.4 56.7 78.6 94.7 56.6 31.4 70.2 63.7 52.3 85.6 54.4 85.2 80.0 96.7 66.9 47.5 73.8 31.9 49.5 88.6 69.6 76.0 62.5 20.2 40.2 19.1 23.1 51.0 19.8 20.2 17.7 21.7 69.5 21.6 23.4 21.0 3.7 77.2 34.8 25.4 26.7 28.8 15.9 20.0 18.3 21.7 16.2 14.7 11.0 13.3 12.8 14.6 16.5 23.1 14.9 6.4 7.5 14.4 13.1 16.6 15.2 21.6 13.1 13.2 13.2 10.3 6.2 10.0 20.1 18.4 20.9 35.4 18.1 14.0 31.3 24.5 10.7 13.5 17.4 14.3 10.2 17.2 61.9 17.5 42.8 17.4 14.3 11.2 6.3 18.1 18.2 17.5 37.0 10.1 44.7 14.6 14.2 19.4 45.8 11.8 11.1 17.2 14.2 15.0 19.7 8.9 26.8 27.2 39.2 19.4 11.6 14.7 12.2 19.9 14.2 48.6 15.9 12.7 6.6 11.1 16.1 14.7 17.4 20.1 20.3 25.6 10.5 24.8 21.3 14.8 KANSL1L "C2orf67, FLJ23861, FLJ32349, KIAA1267L, MSL1v2" ENSG00000144445 "KAT8 regulatory NSL complex subunit 1 like" A0AUZ9 2 210021421-210171409 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 198.9" "Cell type enhanced" "Detected in many" "Astrocytes: 113.6;Inhibitory neurons: 117.9;Microglial cells: 103.0;Oligodendrocyte precursor cells: 190.5;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043102, HPA046790" Uncertain Approved Cytosol NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA043102: AB_2678316, HPA046790: AB_2679808" "unprognostic (3.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.55e-3)" "unprognostic (1.45e-2)" "unprognostic (2.55e-3)" "unprognostic (5.52e-2)" "unprognostic (1.46e-1)" "unprognostic (5.99e-3)" "unprognostic (4.65e-2)" "unprognostic (5.89e-3)" "unprognostic (5.75e-2)" "unprognostic (5.95e-3)" "unprognostic (7.44e-2)" "unprognostic (4.60e-2)" "unprognostic (3.21e-2)" "unprognostic (1.30e-3)" 11.6 8.3 10.7 6.2 13.5 5.5 10.3 14.3 9.2 14.4 8.9 9.9 6.5 18.7 17.4 6.9 13.2 15.7 9.7 9.7 11.7 22.7 9.4 11.9 6.7 11.3 12.6 28.5 15.2 198.9 10.0 8.3 12.0 16.9 6.8 12.5 10.0 17.0 12.1 13.3 6.7 13.3 10.6 6.3 12.4 25.3 10.8 26.7 19.7 18.4 5.2 13.6 11.3 17.7 2.7 1.4 14.5 6.1 11.7 8.7 4.0 4.1 5.4 2.7 7.4 2.7 10.9 7.9 5.5 2.8 6.5 3.8 3.4 1.5 4.3 3.4 2.7 6.3 6.1 4.6 7.3 7.4 4.3 5.5 6.5 2.7 1.9 11.5 6.1 7.2 4.5 7.1 4.1 2.7 8.5 19.7 8.4 4.8 1.9 6.1 3.9 6.1 16.0 4.0 9.0 8.5 3.7 2.3 2.9 14.4 2.5 16.1 4.9 5.3 4.3 1.9 3.1 4.9 2.2 7.7 7.0 3.5 7.1 0.2 0.3 0.5 0.2 0.4 0.2 0.1 0.2 0.2 0.4 0.3 0.3 0.3 0.4 0.6 0.1 0.3 0.1 0.1 10.7 13.5 14.3 9.2 9.7 11.7 11.3 12.6 12.0 10.6 10.8 17.7 12.8 28.9 20.1 113.6 4.6 7.4 6.7 3.9 11.4 8.6 5.4 6.7 9.2 20.0 6.6 31.3 14.6 1.7 1.5 2.3 3.9 13.2 30.3 22.3 17.0 8.8 6.0 4.6 79.0 5.5 0.9 14.2 9.2 14.7 10.8 23.6 6.4 7.4 2.7 5.0 117.9 3.2 8.2 2.8 6.7 22.2 14.6 8.5 7.2 103.0 5.5 9.6 4.1 190.5 158.9 6.7 4.7 30.1 3.0 7.0 2.0 15.8 36.0 8.7 13.1 31.1 15.6 44.9 7.8 5.5 11.1 1.9 2.7 6.6 2.8 4.1 ACADL "ACAD4, LCAD" ENSG00000115361 "Acyl-CoA dehydrogenase long chain" P28330 2 210187126-210225447 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.0;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 70.9;Early spermatids: 85.6;Late spermatids: 69.4;Leydig cells: 46.9;Peritubular cells: 46.6;Proximal tubular cells: 31.5" "Group enriched" "Detected in many" 8 "liver cancer: 2.2;prostate cancer: 6.8;renal cancer: 8.8;thyroid cancer: 4.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;RPTEC TERT1: 2.6;SuSa: 2.3;U-2 OS: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011990 Enhanced Supported NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" "HPA011990: AB_1844465" "unprognostic (6.29e-3)" "unprognostic (7.61e-2)" "unprognostic (1.40e-1)" "unprognostic (1.53e-1)" "unprognostic (1.33e-2)" "unprognostic (7.66e-3)" "unprognostic (3.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.99e-1)" "prognostic favorable (1.58e-11)" "unprognostic (4.22e-3)" "unprognostic (1.18e-4)" "unprognostic (8.81e-3)" "unprognostic (1.06e-1)" 11.9 1.1 0.8 0.1 0.8 0.0 8.0 0.7 1.1 3.4 0.9 0.5 0.0 0.7 1.1 0.5 4.0 0.6 3.1 0.7 1.2 19.8 28.0 10.1 0.0 0.8 0.8 12.7 28.4 4.5 2.9 1.0 0.8 20.6 0.1 0.0 6.8 4.8 9.5 2.8 0.4 0.1 0.8 0.0 5.6 3.1 0.7 1.5 23.7 5.0 0.0 1.0 3.8 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.6 0.5 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 0.7 1.1 0.7 1.2 0.8 0.8 0.8 0.8 0.7 0.9 0.2 28.9 70.9 1.0 0.0 0.6 1.4 1.1 1.2 0.2 1.3 0.5 1.1 8.6 7.6 22.0 2.1 8.8 0.0 0.0 15.6 4.0 85.6 7.1 0.4 0.2 0.0 0.0 0.2 11.9 0.3 4.9 3.6 5.9 2.5 0.8 0.7 23.0 0.5 0.0 13.3 0.0 0.0 0.3 0.4 69.4 46.9 0.4 0.0 4.7 0.0 0.2 0.0 7.5 0.3 3.9 0.0 46.6 0.0 8.2 0.0 31.5 2.4 0.2 0.0 7.6 13.7 0.7 0.7 0.7 1.0 6.3 0.4 0.1 0.0 0.7 MYL1 ENSG00000168530 "Myosin light chain 1" P05976 2 210290150-210315174 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 88 "skeletal muscle: 21805.2;tongue: 15591.3" "Cell type enriched" "Detected in some" 246 "Skeletal myocytes: 492.9" "Group enriched" "Detected in some" 18 "head and neck cancer: 36.0;prostate cancer: 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HSkMC: 51.4" "Region enriched" "Detected in single" 4 "olfactory bulb: 4.0" "Low region specificity" "Detected in all" "HPA046859, HPA063034, HPA073827" Enhanced "Intracellular and membrane" NA NA 21000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "HPA046859: AB_2679842, HPA063034: AB_2684927, HPA073827: " "prognostic unfavorable (6.59e-4)" "unprognostic (1.88e-1)" 2.3 0.5 0.1 0.0 0.1 0.0 3.3 0.0 0.1 0.1 0.0 1.1 0.0 0.5 0.0 212.7 0.0 0.0 2.0 0.1 0.0 0.7 1.0 0.9 0.0 0.0 0.0 0.6 1.1 0.0 0.4 0.0 0.0 164.2 0.0 0.0 170.2 0.0 21805.2 4.0 0.7 0.0 0.0 0.4 0.7 0.5 0.0 7.4 2.3 15591.3 0.9 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 492.9 2.0 0.1 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 LANCL1 "GPR69A, p40" ENSG00000115365 "LanC like 1" O43813 2 210431249-210477652 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.7" "Cell type enhanced" "Detected in all" "Early spermatids: 140.5;Inhibitory neurons: 157.1;Oligodendrocytes: 599.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034994 Enhanced Uncertain Microtubules NA NA 22000 "Cluster 44: Non-specific - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Microtubules "HPA034994: AB_10601936" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" "unprognostic (1.50e-2)" "unprognostic (1.98e-1)" "unprognostic (2.67e-2)" "unprognostic (2.02e-2)" "unprognostic (1.20e-1)" "unprognostic (6.10e-2)" "unprognostic (9.76e-2)" "unprognostic (2.82e-2)" "unprognostic (2.08e-1)" "unprognostic (2.13e-3)" "unprognostic (1.23e-1)" "unprognostic (9.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.06e-1)" 28.1 26.8 57.3 15.5 91.9 19.1 33.6 85.2 81.5 23.1 21.5 22.1 21.5 28.8 19.6 29.5 23.4 23.0 40.9 59.0 67.7 37.6 23.6 21.2 26.7 95.1 79.4 32.1 24.6 64.9 19.2 22.1 89.0 33.0 22.7 48.5 20.3 31.7 28.5 42.2 20.7 33.0 92.8 23.3 19.0 53.9 77.5 40.0 24.3 51.2 27.7 21.4 16.6 140.7 26.3 29.2 45.9 46.8 51.3 71.9 32.0 39.3 50.3 35.5 46.4 32.8 29.4 22.5 50.3 44.9 57.8 26.6 30.2 63.6 59.4 26.1 32.4 39.6 96.1 58.3 42.5 50.5 13.6 52.1 51.2 46.7 37.8 80.3 52.2 68.3 50.1 35.6 46.4 23.1 68.5 27.9 30.7 31.9 20.2 30.5 64.1 33.4 65.2 25.4 43.6 60.4 46.0 97.5 51.2 67.3 33.2 26.7 53.5 62.2 41.4 32.9 41.8 21.8 43.8 31.3 58.4 38.5 73.4 8.6 2.5 6.8 11.8 5.3 11.5 7.9 10.4 11.8 8.3 8.8 11.0 12.7 0.8 8.1 8.5 7.3 11.7 6.8 57.3 91.9 85.2 81.5 59.0 67.7 95.1 79.4 89.0 92.8 77.5 140.7 13.5 12.8 14.2 36.2 11.6 26.3 10.0 13.2 31.3 27.2 19.0 13.5 35.7 10.0 12.3 20.2 18.8 10.8 12.3 5.9 15.6 8.7 140.5 11.6 12.6 13.4 6.7 17.9 68.4 12.0 5.6 16.1 9.2 10.7 6.3 24.0 11.4 20.1 8.8 50.5 157.1 7.6 12.2 10.3 6.4 114.7 13.1 5.0 16.0 20.6 4.5 20.7 15.5 70.4 599.1 5.3 6.0 19.2 11.0 6.5 9.2 18.8 14.2 24.1 19.7 14.8 22.0 41.7 19.0 25.3 33.1 5.1 13.8 14.8 12.7 8.1 CPS1 ENSG00000021826 "Carbamoyl-phosphate synthase 1" P31327 2 210477682-210679107 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Urea cycle" "Allosteric enzyme, Ligase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 1063.2" "Cell type enriched" "Detected in many" 19 "Hepatocytes: 2075.1" "Cancer enriched" "Detected in many" 8 "liver cancer: 136.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 347.6;SiHa: 65.1;SK-BR-3: 98.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003781, HPA021400" Enhanced Supported "Nucleoli,Nucleoli rim" NA NA 8300000 "Cluster 85: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "Nucleoli, Nucleoli rim" "CAB003781: , HPA021400: AB_1847197" "unprognostic (1.67e-2)" "unprognostic (3.72e-2)" "unprognostic (4.02e-2)" "unprognostic (7.21e-7)" "unprognostic (3.81e-2)" "unprognostic (2.52e-1)" "prognostic favorable (6.93e-5)" "unprognostic (1.23e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-2)" "unprognostic (5.38e-2)" "unprognostic (1.94e-3)" "unprognostic (2.38e-4)" "unprognostic (5.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.14e-2)" "unprognostic (3.74e-2)" 2.5 0.4 1.0 0.4 10.0 0.1 1.5 4.9 1.7 0.9 0.1 0.8 211.8 1.6 2.8 1.5 0.9 1.6 1.2 0.7 2.3 1.9 1063.2 1.0 0.3 6.9 8.7 2.9 0.8 0.1 0.9 2.5 6.0 0.8 0.4 0.3 0.5 0.8 0.6 1.4 123.4 2.1 3.4 1.2 0.6 6.0 5.8 0.3 1.7 0.5 0.2 0.6 0.7 6.3 0.9 9.7 14.0 11.7 11.6 16.5 18.0 6.1 6.4 6.3 9.2 1.8 0.0 2.7 0.4 5.3 9.6 3.0 0.5 10.8 15.9 0.0 4.5 10.0 347.6 15.2 2.8 4.0 0.0 9.2 6.2 12.8 13.0 18.7 0.4 4.2 10.3 0.8 10.4 2.8 0.3 0.7 6.3 0.0 1.8 0.7 14.6 1.6 13.2 0.2 0.5 1.1 65.1 98.9 8.1 20.0 0.1 1.6 7.7 17.5 5.8 5.9 13.0 0.0 0.7 0.0 12.5 11.6 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 10.0 4.9 1.7 0.7 2.3 6.9 8.7 6.0 3.4 5.8 6.3 0.4 12.8 8.4 6.2 3.6 2.2 0.6 0.9 1.2 1.4 1.3 1.5 1.1 15.7 3.9 1.8 8.4 0.4 0.4 0.1 0.0 0.2 35.5 1.0 2.1 2.0 0.0 18.7 12.1 0.2 0.4 2.6 0.0 1.6 3.8 0.3 16.8 2075.1 0.2 0.0 6.2 13.5 0.0 27.2 2.9 6.5 2.5 0.8 1.8 3.7 0.2 0.7 0.0 3.0 8.8 0.0 2.5 1.2 0.1 1.1 105.6 1.0 1.3 2.3 0.0 1.8 2.3 0.6 1.8 1.5 1.8 20.8 1.8 3.5 41.2 0.4 ERBB4 "ALS19, HER4" ENSG00000178568 "Erb-b2 receptor tyrosine kinase 4" Q15303 2 211375717-212538841 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Lactation, Transcription, Transcription regulation" "Activator, Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;fallopian tube: 11.2" "Cell type enhanced" "Detected in many" "Astrocytes: 2020.2;Inhibitory neurons: 6091.7;Oligodendrocyte precursor cells: 2369.0;Oligodendrocytes: 1049.9" "Group enriched" "Detected in many" 4 "breast cancer: 4.1;endometrial cancer: 2.1;glioma: 1.2;ovarian cancer: 2.8;testis cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.9;EFO-21: 5.1;HEK 293: 3.8;RPTEC TERT1: 5.6;SCLC-21H: 3.1;T-47d: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000276, HPA012016, CAB025522" Enhanced NA NA 220000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB000276: , CAB025522: , HPA012016: AB_1846541" "unprognostic (1.48e-1)" "unprognostic (3.28e-1)" "unprognostic (4.31e-3)" "unprognostic (1.76e-3)" "unprognostic (3.59e-1)" "unprognostic (2.75e-1)" "unprognostic (2.88e-1)" "unprognostic (9.56e-2)" "unprognostic (2.07e-1)" "unprognostic (4.67e-3)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "unprognostic (7.14e-3)" "unprognostic (1.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.14e-1)" "unprognostic (4.11e-2)" 0.3 0.4 10.0 0.0 13.3 0.0 5.6 10.5 11.5 2.9 0.0 0.1 0.0 0.2 0.0 0.1 11.2 0.0 3.0 9.9 12.7 5.1 0.0 0.8 0.0 4.9 16.9 0.1 0.6 3.1 2.4 0.1 7.6 0.3 0.0 2.0 4.7 1.2 1.5 0.3 0.0 0.0 4.3 0.0 0.4 3.3 8.0 0.0 1.6 1.7 0.0 0.1 0.1 6.1 0.0 0.0 6.9 0.2 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 5.1 0.7 0.0 0.3 0.2 0.0 0.0 0.1 3.8 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 5.6 0.3 3.1 0.2 0.0 0.1 0.1 0.1 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.3 10.5 11.5 9.9 12.7 4.9 16.9 7.6 4.3 8.0 6.1 0.4 0.0 12.6 2020.2 0.0 0.6 0.9 1.1 0.6 15.9 45.6 17.0 27.2 0.0 10.2 12.9 0.0 0.0 0.2 0.0 5.9 0.5 6.7 25.4 1.0 1.0 0.0 0.0 62.0 0.5 0.2 1.8 0.0 25.8 0.0 5.4 0.0 0.0 0.1 0.0 6091.7 0.0 2.0 0.0 0.3 2.2 1.8 0.3 3.6 96.5 0.0 9.1 0.0 2369.0 1049.9 0.0 0.0 0.4 0.0 1.6 0.0 0.2 28.1 1.9 6.6 4.1 3.0 1.8 2.6 0.2 1.3 0.0 0.2 0.0 0.0 1.2 IKZF2 "Helios, ZNFN1A2" ENSG00000030419 "IKAROS family zinc finger 2" Q9UKS7 2 212999691-213152427 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.3" "Cell type enhanced" "Detected in many" "Astrocytes: 77.4;Oligodendrocyte precursor cells: 100.5;Oligodendrocytes: 78.3;Squamous epithelial cells: 47.8;Urothelial cells: 51.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 4.8;NK-cells: 5.5;T-cells: 5.8" "Cell line enhanced" "Detected in many" "JURKAT: 70.5;MOLT-4: 31.1;RT4: 28.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA059142 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA059142: AB_2683923" "unprognostic (2.29e-1)" "unprognostic (1.04e-1)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (3.03e-1)" "unprognostic (5.12e-2)" "unprognostic (1.37e-1)" "unprognostic (1.01e-2)" "unprognostic (1.21e-1)" "unprognostic (3.56e-3)" "unprognostic (4.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.93e-3)" "unprognostic (7.09e-2)" 2.1 2.0 2.6 3.8 5.5 5.5 2.3 3.2 3.2 3.4 0.7 1.8 0.8 1.9 3.2 19.4 2.8 3.1 1.9 2.9 3.8 1.5 1.4 2.9 7.0 5.2 3.5 2.0 2.0 5.2 1.9 2.0 5.3 3.3 1.7 5.5 8.4 4.3 4.1 9.1 1.2 0.8 3.2 5.5 4.4 2.5 3.9 40.3 7.8 1.6 6.8 9.6 8.3 7.4 2.8 1.0 5.3 0.3 17.1 17.2 3.3 3.4 3.9 0.8 1.7 1.4 4.6 3.7 4.4 2.0 0.4 6.5 0.1 1.8 2.7 0.0 0.9 1.9 3.6 0.5 0.1 8.9 0.6 16.9 1.6 0.1 0.5 4.3 0.0 70.5 1.2 3.1 1.6 5.2 31.1 8.9 1.1 2.2 0.8 18.1 3.5 0.0 1.5 28.6 1.6 1.0 0.0 3.6 0.0 4.4 4.8 0.9 9.2 4.9 3.8 2.3 0.7 6.0 2.0 20.6 2.4 0.0 1.1 3.9 0.0 4.8 1.8 0.0 4.9 0.2 0.6 1.4 0.0 1.0 0.3 1.5 0.0 5.5 0.0 0.5 5.8 0.3 2.6 5.5 3.2 3.2 2.9 3.8 5.2 3.5 5.3 3.2 3.9 7.4 2.1 9.6 12.6 77.4 5.2 5.9 23.2 7.9 11.4 4.8 5.1 2.2 7.6 1.5 19.5 7.3 4.2 4.3 27.4 2.8 0.0 2.3 1.3 16.1 1.8 2.4 3.0 9.0 17.7 3.1 1.2 2.7 8.6 18.1 3.8 2.5 2.5 2.2 2.1 0.0 19.9 2.3 4.1 2.4 2.1 0.7 1.8 2.8 1.8 31.9 1.3 3.0 39.1 100.5 78.3 3.6 1.0 2.2 13.9 15.9 1.1 1.0 31.7 7.3 0.0 10.2 4.5 0.8 0.7 47.8 8.7 4.0 22.1 2.0 1.4 51.8 SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284379-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.1;Inhibitory neurons: 273.7;Respiratory ciliated cells: 330.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA037542: AB_10672353" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.90e-4)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-1)" "unprognostic (1.17e-1)" 16.3 16.8 36.6 6.4 37.4 2.4 20.8 35.1 45.9 21.0 39.0 16.5 18.8 18.2 31.6 26.1 46.5 22.0 22.2 34.2 37.8 30.4 18.8 10.8 11.5 38.8 39.6 25.8 15.5 24.4 29.7 9.8 37.8 22.1 17.2 21.5 15.7 20.5 10.3 24.9 10.9 12.1 40.9 8.0 26.1 46.3 38.4 13.0 26.4 10.8 13.8 18.9 19.4 40.6 26.8 9.9 29.4 0.0 19.3 35.0 0.2 14.3 17.1 18.3 19.3 20.8 28.8 11.1 16.7 16.0 29.3 18.5 13.4 17.4 38.6 0.0 10.5 5.8 28.0 24.6 21.9 6.3 0.1 30.1 23.5 16.3 9.5 25.0 7.6 11.6 18.8 12.3 18.4 0.0 21.4 0.1 16.3 0.0 8.7 22.6 30.9 0.5 29.4 25.8 21.4 25.1 16.3 15.1 21.3 24.2 70.3 2.7 7.8 17.2 9.2 9.3 15.1 20.0 9.7 0.4 28.6 0.0 8.0 2.0 0.3 0.9 8.1 1.3 11.7 9.3 9.1 10.4 3.1 8.5 12.0 10.4 0.5 15.4 0.9 5.1 9.4 3.4 36.6 37.4 35.1 45.9 34.2 37.8 38.8 39.6 37.8 40.9 38.4 40.6 17.7 16.0 19.5 89.5 10.7 42.3 46.6 82.8 22.8 47.6 38.0 45.6 67.5 74.4 73.6 40.5 95.9 50.6 7.5 17.1 76.3 44.0 243.1 207.0 31.3 18.5 38.2 9.0 205.9 24.9 20.8 30.8 32.1 30.3 10.1 34.0 12.8 16.9 11.7 40.4 273.7 37.8 101.7 4.6 9.6 86.2 41.3 5.9 23.2 42.2 29.2 82.7 8.2 92.0 74.9 27.3 18.8 44.8 9.4 25.4 9.4 94.9 330.0 69.0 13.1 30.8 36.1 167.9 31.0 64.6 56.4 23.5 12.9 55.3 39.8 53.8 VWC2L ENSG00000174453 "Von Willebrand factor C domain containing 2 like" B2RUY7 2 214411054-214578976 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 2.7;retina: 1.4" "Group enriched" "Detected in some" 21 "Excitatory neurons: 67.4;Inhibitory neurons: 132.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA044815, HPA059414" Uncertain "Secreted - unknown location" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044815: AB_10962359, HPA059414: AB_2684007" "unprognostic (8.77e-2)" "unprognostic (2.83e-3)" "unprognostic (2.05e-2)" "unprognostic (8.49e-2)" "unprognostic (1.51e-3)" "unprognostic (4.36e-1)" "unprognostic (2.56e-2)" "unprognostic (2.05e-1)" "unprognostic (3.89e-1)" 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.2 0.0 0.0 0.0 0.0 0.8 1.8 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.7 0.1 2.1 2.7 2.2 0.8 1.8 1.8 0.2 2.3 1.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 67.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 132.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.1 0.0 4.5 2.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 68.6;Basal prostatic cells: 62.2;Suprabasal keratinocytes: 74.4;Urothelial cells: 67.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: AB_2061237, HPA035354: AB_2674585, HPA044864: AB_2679119" "unprognostic (4.85e-2)" "unprognostic (1.87e-2)" "unprognostic (1.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.57e-2)" "unprognostic (1.03e-2)" "unprognostic (6.25e-4)" "unprognostic (1.99e-1)" "unprognostic (2.16e-2)" "unprognostic (3.92e-3)" "unprognostic (2.80e-2)" "unprognostic (7.41e-2)" "unprognostic (1.94e-8)" "unprognostic (3.94e-2)" "unprognostic (2.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" 1.8 0.6 3.0 2.7 4.6 11.4 2.9 2.2 2.7 3.1 0.2 2.9 2.3 3.3 2.6 5.1 1.9 2.0 1.5 2.3 4.1 0.8 1.0 2.5 5.5 3.8 3.2 2.3 1.6 2.3 1.2 2.3 3.9 2.9 3.6 2.0 1.9 3.6 4.2 8.8 2.1 3.9 3.9 2.6 1.9 6.6 4.1 7.0 1.4 2.3 6.6 2.1 3.8 4.2 12.3 8.8 20.2 9.3 2.7 4.0 12.0 17.3 10.6 17.8 21.8 12.0 12.2 12.6 7.6 8.5 9.5 12.7 16.5 10.5 22.7 11.5 6.4 12.5 13.8 8.7 0.9 13.9 12.7 4.7 1.1 15.0 8.1 4.5 6.1 14.7 7.9 36.0 13.7 10.7 27.9 12.5 14.3 7.9 3.7 24.7 19.8 11.2 3.9 14.0 5.8 8.8 15.0 14.7 5.3 10.9 16.3 13.4 4.7 18.0 14.0 11.7 13.6 10.2 12.6 28.0 7.6 11.3 13.4 3.9 2.0 5.8 4.6 4.0 3.2 9.7 5.4 5.5 3.6 8.2 2.4 4.0 0.3 7.3 3.8 6.9 17.1 2.3 3.0 4.6 2.2 2.7 2.3 4.1 3.8 3.2 3.9 3.9 4.1 4.2 12.3 6.4 2.2 14.7 13.0 68.6 62.2 13.0 14.2 3.3 9.9 14.1 17.4 17.2 12.7 9.2 0.0 18.2 11.3 8.2 3.9 8.0 9.2 13.3 11.9 9.6 1.2 34.5 5.5 6.9 16.0 10.0 10.2 18.0 15.2 28.2 10.0 4.2 12.5 1.7 15.4 13.1 8.2 10.1 12.2 5.7 6.2 11.2 3.6 15.9 16.6 4.4 9.2 19.6 31.7 6.5 6.5 10.1 22.0 22.9 3.2 0.7 12.3 6.8 19.7 15.4 16.9 27.6 43.4 28.6 74.4 5.1 13.4 10.5 14.7 67.2 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 FN1 "CIG, FINC, GFND2, LETS, MSF" ENSG00000115414 "Fibronectin 1" P02751 2 215360440-215436073 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Angiogenesis, Cell adhesion, Cell shape" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1725.9;placenta: 2928.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 2583.6;Fibroblasts: 562.6;Hepatocytes: 1012.4;Smooth muscle cells: 450.2" "Cancer enhanced" "Detected in all" "thyroid cancer: 833.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 34405.9;HSkMC: 16044.5;hTERT-HME1: 9585.3;hTERT-RPE1: 10587.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000126, HPA027066" Enhanced "Secreted to blood" NA NA 47000000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "CAB000126: , HPA027066: AB_10602500" "unprognostic (8.08e-2)" "unprognostic (1.09e-3)" "unprognostic (2.20e-2)" "unprognostic (3.45e-3)" "unprognostic (1.82e-2)" "unprognostic (3.47e-3)" "unprognostic (3.36e-2)" "unprognostic (5.91e-3)" "unprognostic (2.96e-2)" "unprognostic (2.91e-3)" "unprognostic (1.41e-2)" "unprognostic (2.84e-1)" "prognostic unfavorable (3.44e-8)" "prognostic unfavorable (8.82e-5)" "unprognostic (7.88e-2)" "unprognostic (7.74e-2)" "prognostic unfavorable (3.33e-4)" 151.1 31.4 37.8 131.9 44.8 0.6 76.5 36.3 51.2 135.9 85.9 444.0 33.8 156.1 61.3 251.6 174.5 187.1 410.9 38.9 41.1 42.9 1725.9 785.7 37.3 37.7 39.8 110.0 26.0 19.3 26.2 2928.1 43.5 105.6 237.2 6.0 67.0 428.9 37.7 52.7 103.4 722.6 36.2 14.3 127.2 25.8 112.1 133.8 40.4 148.4 23.9 361.7 87.1 35.3 12.5 84.2 104.6 22.8 4456.5 34405.9 4.8 1799.2 1200.2 1765.3 1259.9 1059.2 43.7 1.2 9.7 6331.7 47.2 192.7 17.4 4220.9 946.9 1.0 7.4 0.8 24.7 3607.2 3192.2 1.2 6.6 16044.5 29.3 4136.5 9585.3 10587.1 2177.2 1.0 8.2 5.0 3673.9 17.0 2.9 1.5 52.7 2.4 15.2 1.0 2.4 8.0 47.4 13.7 6.0 25.0 213.7 116.4 1219.8 4649.5 19.4 3.2 4161.0 2553.1 269.9 2837.4 355.6 4.4 1.6 1.6 3161.2 1.0 694.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.8 44.8 36.3 51.2 38.9 41.1 37.7 39.8 43.5 36.2 112.1 35.3 138.9 67.3 67.8 13.4 2.3 55.1 4.1 227.0 2.2 6.4 4.2 5.2 36.3 30.0 34.0 16.5 0.0 216.6 2.3 3.4 0.0 6.5 1.8 6.5 265.8 215.4 21.0 16.8 9.5 9.8 2583.6 562.6 4.1 5.5 18.9 53.5 227.7 1012.4 365.2 1.7 8.1 10.2 12.2 38.0 73.7 4.6 186.4 85.9 110.3 101.2 1.2 1.9 0.0 11.6 10.7 12.5 1.4 88.4 1.7 17.8 0.0 0.6 23.1 8.7 72.3 401.5 450.2 1.6 7.8 5.0 37.4 205.8 11.3 8.5 23.7 1.7 MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Glandular and luminal cells: 34.1;Rod photoreceptor cells: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA068583: AB_2686009" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.13e-2)" "unprognostic (3.70e-1)" "unprognostic (7.37e-2)" "unprognostic (2.39e-1)" "unprognostic (5.85e-3)" "unprognostic (8.11e-3)" "unprognostic (8.93e-2)" "unprognostic (6.38e-3)" "unprognostic (6.62e-3)" "unprognostic (6.92e-2)" "prognostic favorable (4.20e-4)" "unprognostic (9.99e-2)" 5.9 8.2 3.9 5.4 8.9 5.9 21.4 17.9 5.6 6.7 6.2 5.6 6.4 3.4 5.0 29.8 5.8 2.8 0.7 4.6 4.5 5.4 17.8 10.3 10.8 5.6 4.7 2.5 2.2 7.3 7.6 7.7 5.9 2.4 5.8 46.9 4.9 6.1 2.7 20.2 5.5 1.8 3.3 4.4 6.8 1.1 6.5 9.9 6.6 0.9 15.1 5.5 14.3 5.0 20.9 5.1 5.9 3.5 3.9 2.1 13.1 7.0 5.6 4.6 8.9 24.3 15.5 6.7 6.0 4.3 11.5 13.0 17.9 26.5 10.1 14.1 15.1 10.6 5.6 43.5 2.3 6.0 3.9 3.9 11.2 5.3 7.4 4.6 4.0 15.2 5.3 17.8 2.9 82.8 17.0 5.7 23.3 12.4 4.8 9.8 13.9 10.7 12.3 29.3 16.4 8.6 4.4 36.4 40.3 13.7 20.2 2.8 0.5 9.8 2.5 5.0 10.7 23.0 15.3 17.5 6.0 22.2 7.5 1.6 0.1 0.2 0.7 0.1 1.2 1.1 0.6 1.1 0.1 0.6 0.3 0.5 0.8 0.8 0.2 2.1 1.0 0.1 3.9 8.9 17.9 5.6 4.6 4.5 5.6 4.7 5.9 3.3 6.5 5.0 0.6 3.2 13.4 7.8 4.3 2.7 12.1 0.6 9.6 14.4 24.1 12.1 0.8 2.8 9.2 7.3 60.5 21.7 8.5 3.8 3.9 3.2 0.3 14.0 1.9 1.1 1.8 2.1 21.1 2.5 4.7 1.8 5.6 34.1 1.3 0.6 1.4 8.3 13.4 1.7 21.4 1.8 2.0 0.8 3.0 0.0 2.5 4.0 5.4 6.5 21.3 7.6 2.1 8.5 12.8 7.5 4.6 7.5 7.0 7.0 3.1 1.1 3.0 40.1 6.6 1.2 1.2 1.1 4.6 28.7 1.6 25.9 4.0 1.0 2.9 22.6 PECR "HSA250303, SDR29C1, TERP" ENSG00000115425 "Peroxisomal trans-2-enoyl-CoA reductase" Q9BY49 2 215996329-216082955 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 160.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 91.0;Proximal enterocytes: 49.5;Proximal tubular cells: 79.1" "Cancer enhanced" "Detected in all" "liver cancer: 30.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 38.3;RPTEC TERT1: 35.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021593, HPA022539" Enhanced Supported Peroxisomes NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Peroxisomes "HPA021593: AB_1855177, HPA022539: AB_1855178" "unprognostic (7.97e-2)" "unprognostic (1.08e-1)" "unprognostic (5.72e-2)" "unprognostic (1.32e-3)" "unprognostic (2.90e-1)" "unprognostic (6.40e-2)" "unprognostic (1.16e-3)" "unprognostic (3.56e-2)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-3)" "unprognostic (5.61e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.63e-2)" "unprognostic (1.84e-2)" "unprognostic (7.75e-2)" "unprognostic (6.64e-2)" 25.4 5.4 2.7 2.9 3.1 7.1 10.2 3.8 2.9 4.5 6.0 8.7 26.0 3.3 4.1 3.1 8.1 9.7 2.4 2.7 2.8 33.9 160.2 6.4 3.9 3.2 3.1 4.1 4.8 7.2 3.2 1.0 3.3 5.0 7.5 2.2 5.6 3.4 6.8 4.2 20.1 3.2 2.6 3.0 3.9 0.5 3.0 3.4 16.1 5.2 3.8 2.3 2.3 3.7 6.0 6.6 2.6 0.1 15.7 5.7 3.1 1.4 3.3 3.7 6.3 7.6 17.1 0.1 11.9 3.5 9.2 1.4 7.5 8.7 6.5 9.5 7.7 7.8 3.6 38.3 15.7 2.0 5.1 5.0 6.1 3.9 5.5 5.6 3.8 4.6 3.3 8.6 8.2 4.4 2.4 2.2 4.8 0.1 4.9 5.3 5.0 0.9 35.9 1.0 3.6 5.2 3.6 7.4 15.6 6.2 8.6 6.5 0.0 2.4 2.5 6.0 4.3 9.8 8.9 3.1 5.3 2.8 5.6 1.2 4.2 1.5 6.5 1.6 7.7 4.3 8.8 7.5 1.5 5.7 9.2 6.1 4.5 9.9 2.3 0.2 16.6 4.1 2.7 3.1 3.8 2.9 2.7 2.8 3.2 3.1 3.3 2.6 3.0 3.7 4.3 6.4 13.6 6.5 7.0 3.7 4.7 4.0 3.4 10.8 2.4 2.9 3.7 35.8 3.4 29.5 14.6 3.9 5.9 11.5 13.7 13.2 0.1 10.1 2.7 3.9 7.2 9.4 15.4 3.8 7.3 5.0 7.7 6.3 1.3 2.0 6.8 91.0 9.6 3.3 18.4 8.0 6.1 4.7 3.7 0.3 5.6 5.5 10.6 8.4 27.4 10.1 9.2 8.5 10.6 5.0 17.7 8.2 5.9 2.0 49.5 79.1 13.1 6.4 0.0 6.6 4.4 0.1 1.6 4.9 2.8 1.6 11.4 1.9 14.6 2.7 TMEM169 FLJ34263 ENSG00000163449 "Transmembrane protein 169" Q96HH4 2 216081866-216102783 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;retina: 3.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.4;Cone photoreceptor cells: 22.9;Excitatory neurons: 13.1;Inhibitory neurons: 13.9;Oligodendrocyte precursor cells: 11.1;Oligodendrocytes: 9.3;Rod photoreceptor cells: 11.6" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 7.3;RPTEC TERT1: 12.3;SCLC-21H: 9.9;SH-SY5Y: 14.5" "Low region specificity" "Detected in all" "HPA062462, HPA062797, HPA070657, HPA074877" Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" Centrosome "HPA062462: AB_2732684, HPA062797: AB_2732690, HPA070657: AB_2686293, HPA074877: " "unprognostic (5.15e-2)" "unprognostic (2.93e-1)" "unprognostic (7.87e-3)" "unprognostic (4.69e-7)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.97e-1)" "unprognostic (4.43e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (1.00e-1)" "unprognostic (1.35e-1)" "unprognostic (2.79e-2)" "unprognostic (7.51e-3)" "unprognostic (4.69e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-1)" 0.5 1.0 1.4 1.0 3.0 0.3 0.2 1.5 2.6 0.7 0.0 0.4 0.7 0.3 0.7 0.2 1.0 0.8 0.4 2.3 2.1 1.8 1.7 0.6 1.0 2.6 2.1 0.3 0.3 0.1 0.8 0.1 2.8 0.4 0.3 3.4 0.2 0.3 0.3 0.5 0.6 0.4 1.0 1.0 0.2 0.3 1.7 1.0 2.6 0.3 0.7 0.2 0.1 2.8 0.0 0.3 7.3 0.1 1.0 0.0 0.0 0.3 0.2 0.2 0.8 0.3 2.4 0.0 5.8 0.3 0.4 0.1 0.9 0.0 0.2 1.4 0.3 2.9 0.1 1.4 1.9 0.1 0.5 0.6 0.6 0.5 0.7 1.8 0.0 0.9 0.0 0.3 6.3 0.8 0.2 0.1 4.1 0.0 0.0 1.4 2.0 0.0 12.3 0.0 9.9 14.5 0.3 0.1 5.7 4.0 0.5 1.0 0.0 0.2 0.4 0.0 0.4 1.7 2.2 0.4 1.9 0.2 1.4 0.8 1.0 0.1 1.2 1.0 0.9 1.5 2.0 1.4 0.0 1.4 2.1 0.9 2.3 0.3 3.2 0.1 3.7 0.7 1.4 3.0 1.5 2.6 2.3 2.1 2.6 2.1 2.8 1.0 1.7 2.8 0.3 0.0 0.0 2.0 0.9 0.0 0.0 0.0 0.0 14.4 0.1 0.5 0.8 4.3 0.0 5.5 22.9 0.1 0.3 0.0 0.0 0.6 0.0 0.4 0.4 0.2 4.9 0.0 13.1 0.0 0.0 0.2 0.5 0.5 0.0 0.0 1.4 0.8 0.4 0.0 13.9 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.0 3.7 0.2 2.2 3.1 11.1 9.3 0.1 0.6 0.4 0.3 0.1 0.3 2.8 0.1 11.6 0.0 3.6 0.4 0.0 0.7 0.0 0.0 0.0 0.8 0.1 0.2 0.1 XRCC5 "KARP-1, KU80, Ku86, KUB2" ENSG00000079246 "X-ray repair cross complementing 5" P13010 2 216107464-216206303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004468, HPA025813, HPA064685" Supported Enhanced Nucleoplasm NA NA 940000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004468: AB_672929, HPA025813: AB_1858901, HPA064685: AB_2685322" "unprognostic (4.23e-2)" "unprognostic (1.75e-1)" "unprognostic (9.07e-3)" "unprognostic (3.44e-3)" "unprognostic (2.44e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.10e-7)" "unprognostic (4.42e-3)" "unprognostic (1.38e-1)" "unprognostic (1.06e-1)" "unprognostic (3.38e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (2.30e-1)" "unprognostic (2.88e-2)" "unprognostic (3.58e-2)" "unprognostic (6.01e-2)" 79.6 74.0 52.8 102.4 58.4 112.0 114.6 56.0 69.9 96.4 38.1 91.0 82.2 103.3 85.3 96.8 95.8 83.2 77.1 58.1 56.4 100.2 140.6 76.6 127.8 52.4 50.7 104.0 71.7 118.4 61.4 87.1 54.4 84.7 106.6 102.0 71.6 91.3 103.1 91.6 82.3 100.1 59.1 83.9 77.0 69.5 51.0 176.8 129.2 92.7 140.9 131.7 72.7 65.6 234.4 194.9 427.0 230.5 185.5 210.9 256.6 269.9 279.2 307.1 328.5 421.0 225.7 225.6 214.8 239.1 269.2 203.5 425.2 329.5 469.7 215.0 291.0 488.5 282.9 398.0 229.2 437.1 230.0 193.5 172.1 361.2 156.6 218.4 368.0 272.1 314.4 199.7 405.9 225.9 496.7 221.7 498.0 236.0 170.6 429.8 376.7 186.5 331.9 262.6 372.6 314.6 217.8 159.9 201.1 428.5 196.7 325.8 264.2 287.3 241.5 190.6 312.3 240.0 311.4 493.6 223.4 339.5 290.0 253.2 172.7 175.0 153.6 177.1 165.3 121.2 148.1 157.0 168.0 121.6 147.6 149.1 192.7 172.9 217.4 102.1 167.5 330.4 52.8 58.4 56.0 69.9 58.1 56.4 52.4 50.7 54.4 59.1 51.0 65.6 129.0 105.8 126.3 65.6 131.0 113.7 174.0 242.4 90.5 136.7 93.6 87.1 163.0 105.8 190.0 101.2 45.9 210.5 141.6 79.8 97.8 304.3 103.0 147.4 175.4 142.4 133.3 159.4 73.9 235.8 238.8 134.1 74.5 159.1 146.7 140.2 82.8 222.5 157.3 89.2 82.4 90.7 173.0 100.5 85.3 30.0 101.5 130.7 69.4 108.7 310.9 142.0 138.0 93.0 111.4 247.9 70.3 129.4 132.5 137.4 82.8 139.9 160.1 114.0 111.7 142.9 161.3 252.2 179.2 114.7 120.3 165.5 149.7 165.3 112.0 161.2 MARCHF4 "KIAA1399, MARCH-IV, MARCH4, RNF174" ENSG00000144583 "Membrane associated ring-CH-type finger 4" Q9P2E8 2 216257865-216372483 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 4.4;pituitary gland: 6.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 69.0;fHDF/TERT166: 43.8;TIME: 32.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA014348 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA014348: AB_1853578" "unprognostic (4.84e-2)" "unprognostic (1.02e-4)" "unprognostic (1.63e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (6.49e-2)" "unprognostic (5.55e-3)" "unprognostic (1.07e-1)" "unprognostic (6.81e-5)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.09e-3)" 0.0 0.7 2.6 0.0 3.9 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 3.1 2.2 0.0 0.0 0.0 0.0 0.5 4.1 0.0 0.4 0.0 6.2 0.6 1.1 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.2 0.0 2.7 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 12.5 2.5 0.0 0.0 0.2 1.6 0.0 69.0 23.2 14.5 5.1 0.1 1.0 0.0 10.5 43.8 24.2 0.1 0.0 26.7 14.1 0.0 0.0 5.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 13.3 19.6 9.3 19.0 0.0 0.0 0.0 22.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.4 1.9 0.1 0.0 0.0 2.2 0.0 0.0 32.7 22.7 23.9 0.1 18.6 0.0 0.0 0.0 5.2 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.9 0.0 4.4 3.1 2.2 0.5 4.1 1.1 2.7 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMARCAL1 "HARP, HHARP" ENSG00000138375 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1" Q9NZC9 2 216412414-216483053 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 35.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020337 Uncertain Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "HPA020337: AB_2670410" "unprognostic (4.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-2)" "unprognostic (3.39e-2)" "unprognostic (2.68e-2)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.35e-3)" "unprognostic (3.31e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-1)" "unprognostic (7.46e-2)" "unprognostic (2.00e-2)" "unprognostic (2.67e-1)" "unprognostic (1.41e-1)" "unprognostic (1.97e-1)" "unprognostic (3.16e-1)" 9.2 9.8 7.5 8.9 10.3 9.1 8.8 8.0 9.7 10.6 7.6 8.0 6.8 10.7 7.5 9.8 11.0 9.5 8.9 8.0 9.0 7.2 6.7 7.9 13.1 10.6 9.1 16.3 8.2 10.8 9.3 9.1 10.6 8.1 7.4 5.6 8.0 8.9 10.5 10.6 7.9 10.1 8.4 9.7 8.0 10.3 10.2 15.1 10.2 10.6 11.9 8.8 9.0 14.2 16.7 16.3 22.2 12.7 21.5 25.1 21.3 22.0 22.7 23.0 26.1 26.7 20.3 15.0 21.8 27.6 28.8 12.3 19.1 24.4 30.5 45.7 18.9 42.8 12.0 19.9 22.0 11.5 23.9 16.7 25.7 24.9 24.4 24.0 27.6 23.5 42.6 15.8 26.3 12.3 22.2 26.8 16.1 14.7 8.9 24.6 14.6 9.3 18.2 11.4 18.4 11.9 12.0 9.1 18.7 38.2 12.4 18.1 21.3 28.3 13.0 13.7 13.9 18.0 18.6 13.3 28.8 15.6 20.2 25.9 9.5 14.1 12.2 10.5 11.6 9.6 11.5 14.3 14.9 9.2 9.6 11.8 1.7 21.0 18.1 18.0 14.7 8.5 7.5 10.3 8.0 9.7 8.0 9.0 10.6 9.1 10.6 8.4 10.2 14.2 6.3 6.4 6.1 20.2 8.2 0.9 3.3 4.6 8.6 5.1 4.3 3.4 5.0 7.2 3.7 0.0 0.0 10.4 6.7 3.4 5.9 7.4 14.5 10.4 7.2 7.0 3.6 11.4 20.6 3.8 12.2 8.0 5.6 5.8 17.7 11.0 4.2 3.2 9.7 8.4 30.8 3.7 2.0 8.9 3.1 13.7 6.2 6.2 1.8 12.2 10.1 4.7 10.3 24.6 35.9 4.0 13.3 8.6 7.0 1.3 4.7 5.8 4.4 4.8 13.1 6.0 6.8 7.7 4.4 5.3 1.3 7.3 6.5 7.5 5.3 2.0 RPL37A L37A ENSG00000197756 "Ribosomal protein L37a" P61513 2 216498825-216579180 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065327 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 87000 "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA065327: AB_2685469" "unprognostic (9.94e-3)" "unprognostic (2.17e-1)" "unprognostic (2.99e-1)" "unprognostic (3.19e-1)" "unprognostic (5.12e-3)" "unprognostic (6.92e-2)" "unprognostic (1.76e-2)" "unprognostic (2.67e-1)" "unprognostic (8.26e-2)" "unprognostic (2.33e-1)" "unprognostic (2.62e-1)" "unprognostic (8.84e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.49e-1)" "unprognostic (4.92e-2)" "unprognostic (1.05e-2)" "unprognostic (1.67e-1)" 2894.2 2485.3 3571.1 1229.7 3641.9 2540.7 3450.6 3500.1 5561.8 3540.4 3427.6 2751.2 1111.0 2511.3 1607.3 3586.9 2970.5 473.7 2704.2 3470.4 3604.5 2072.8 2064.6 1905.6 1484.2 3596.9 3545.7 5492.1 4241.2 2106.3 2029.8 971.3 3587.7 2527.0 1539.4 1236.7 2385.3 1378.1 5240.2 4441.1 2070.2 1297.7 3658.7 2374.5 2568.6 1257.5 3665.2 3015.1 1910.2 4156.0 2246.3 2758.2 3080.7 3688.7 2117.5 1757.0 3750.8 2542.5 3820.2 6666.2 2783.2 2804.7 3711.8 2778.8 2362.0 4478.9 2000.9 2310.8 3821.8 3450.3 3000.1 2165.8 3570.4 4118.4 2861.6 2653.7 3779.3 3786.9 3130.5 6449.1 6532.0 4206.8 2285.8 7292.0 8500.4 2410.8 6755.9 7614.5 3897.7 4509.9 3008.0 3296.4 3653.4 4222.0 4025.0 8611.8 4350.4 4680.8 1985.4 2874.3 2818.9 2846.9 3975.2 3650.5 2425.5 2719.7 1032.7 3199.3 6926.2 5291.2 2027.5 7146.0 2649.0 2006.9 2201.6 1991.6 3119.4 3471.7 5348.9 4515.3 2242.4 2876.4 2081.6 1025.7 2303.5 546.8 2463.3 1720.1 3379.1 4446.9 3801.3 3078.0 3061.9 4258.4 4343.3 4006.9 281.8 2725.4 1469.9 4230.5 3011.4 6099.2 3571.1 3641.9 3500.1 5561.8 3470.4 3604.5 3596.9 3545.7 3587.7 3658.7 3665.2 3688.7 1310.3 1198.7 1865.0 20.2 3813.1 4936.9 3370.7 3086.2 2318.0 513.1 5676.7 3353.1 1482.9 2713.7 2139.1 1265.3 185.6 3021.4 2978.5 1879.2 3155.8 2994.2 3958.3 1634.1 3979.9 2334.0 2623.6 2835.7 16.8 8453.9 5257.7 1903.5 1194.2 2334.1 2170.9 3057.7 3945.8 4967.1 3060.4 200.2 18.2 4863.9 935.8 4892.5 4112.7 7778.0 5740.1 2453.8 2853.1 15.9 3968.7 2304.7 3980.5 11.1 24.2 6102.8 5240.6 2969.2 2205.6 3694.1 3198.7 3898.4 964.1 755.8 2005.0 4215.6 2775.8 2230.8 1623.5 4320.7 7355.8 3208.5 2814.6 1760.7 5273.7 3405.9 IGFBP2 IBP2 ENSG00000115457 "Insulin like growth factor binding protein 2" P18065 2 216632828-216664436 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 956.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1379.1;Granulosa cells: 1649.7;Hepatocytes: 658.6;Theca cells: 2199.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2139.8;HMC-1: 5110.0;NB-4: 1106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077723 Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 303000000 810000000 "Cluster 48: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "HPA077723: AB_2686853" "unprognostic (2.58e-1)" "unprognostic (5.95e-2)" "unprognostic (1.94e-1)" "unprognostic (3.32e-3)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "unprognostic (2.06e-1)" "unprognostic (9.11e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (2.34e-1)" "unprognostic (1.63e-3)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.22e-5)" "unprognostic (5.04e-2)" "unprognostic (1.07e-1)" "unprognostic (5.83e-2)" "unprognostic (1.22e-1)" 219.5 58.8 15.9 28.3 14.8 21.4 90.5 15.6 30.2 86.9 123.3 85.5 76.8 232.5 59.9 145.6 157.0 26.9 169.2 15.6 16.3 187.3 607.7 71.0 8.8 15.3 21.7 281.7 956.0 12.4 66.9 81.0 19.3 217.3 35.0 2.4 76.4 196.2 23.3 30.8 44.6 49.7 13.2 398.9 492.2 58.0 16.0 33.6 57.8 21.9 14.5 132.6 97.4 13.2 0.1 52.3 402.1 396.3 2139.8 652.9 8.5 125.2 61.9 6.1 0.6 1.2 1.5 0.1 171.7 0.8 15.2 11.5 145.4 156.9 0.6 0.8 84.9 91.3 0.2 26.3 53.3 38.6 5110.0 219.3 15.8 2.5 7.1 12.5 0.2 184.7 3.9 11.7 2.8 103.1 162.8 1106.5 437.4 98.2 4.8 139.2 9.1 2.0 2.0 117.1 84.1 443.4 0.3 3.4 2.6 362.2 332.4 67.3 0.5 1.6 2.4 1.6 6.2 6.2 0.9 9.7 6.0 177.4 478.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 15.9 14.8 15.6 30.2 15.6 16.3 15.3 21.7 19.3 13.2 16.0 13.2 354.3 3.2 0.6 2.0 3.3 13.8 534.0 238.2 19.4 0.2 79.0 498.0 12.5 11.5 40.1 264.8 2.1 1.8 5.4 86.4 29.4 3.0 1.0 153.2 1379.1 149.2 321.0 31.1 4.5 128.4 7.7 296.7 411.8 176.0 4.5 1649.7 92.1 658.6 5.3 0.0 0.8 191.6 54.9 24.1 5.0 4.9 5.6 21.8 3.6 13.1 1.3 3.6 3.1 1.0 1.0 60.7 51.3 79.4 0.4 255.7 4.2 1.2 195.9 1.7 105.2 17.9 435.7 6.0 35.8 103.3 5.5 2.2 16.0 2199.1 133.8 304.0 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 TNP1 ENSG00000118245 "Transition protein 1" P09430 2 216859458-216860064 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1160 "testis: 5953.3" "Group enriched" "Detected in some" 205 "Early spermatids: 41424.6;Late spermatids: 136509.6" "Group enriched" "Detected in some" 58 "liver cancer: 6.0;testis cancer: 4.8" "Region enhanced" "Detected in many" "basal ganglia: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;U-2197: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA044387 Enhanced NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 34: Spermatids - Unknown function" "HPA044387: AB_2678923" "unprognostic (1.67e-1)" 0.9 0.8 1.4 0.4 4.9 0.0 4.0 1.4 1.4 1.0 0.0 0.9 0.8 0.6 0.0 0.8 0.6 0.0 0.8 1.6 0.0 1.1 2.0 0.6 0.1 0.0 0.0 0.8 1.3 0.0 0.8 0.0 0.0 5.1 0.0 0.0 0.8 0.0 2.3 1.4 1.6 0.0 0.0 0.6 1.0 5953.3 1.0 0.0 2.4 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 4.9 1.4 1.4 1.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41424.6 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 136509.6 410.1 26.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 246.7 0.0 0.0 0.0 0.0 0.0 0.0 249.8 0.0 0.1 433.2 234.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 TNS1 "DKFZp586K0617, MXRA6, PPP1R155, TNS" ENSG00000079308 "Tensin 1" Q9HBL0 2 217799588-218033982 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 173.1;Cardiomyocytes: 339.0;Leydig cells: 169.6;Peritubular cells: 504.0;Sertoli cells: 368.1;Smooth muscle cells: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 135.1;ASC TERT1: 74.1;fHDF/TERT166: 66.6;REH: 75.4;TIME: 63.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018774, HPA036089, HPA036090" Approved Enhanced "Focal adhesion sites" NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Focal adhesion sites" "CAB018774: AB_2207032, HPA036089: AB_10796111, HPA036090: AB_10794322" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.13e-2)" "unprognostic (5.46e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-3)" "unprognostic (7.34e-2)" "unprognostic (2.55e-2)" "unprognostic (1.28e-3)" "unprognostic (5.57e-2)" "unprognostic (9.74e-2)" "unprognostic (4.71e-3)" "unprognostic (5.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.49e-2)" "prognostic unfavorable (5.19e-4)" 248.2 60.3 51.6 42.9 98.0 42.3 100.9 71.7 45.5 99.5 45.1 373.4 23.4 253.7 44.3 117.8 136.2 80.4 170.4 34.0 53.4 74.6 39.6 117.2 11.5 82.3 79.2 110.4 55.2 33.2 15.4 54.5 106.4 126.1 41.7 7.7 52.9 225.0 171.6 47.8 78.9 178.0 72.2 70.1 115.2 23.5 80.9 21.5 65.8 207.2 7.5 228.4 82.6 82.9 0.3 0.4 8.9 0.1 135.1 74.1 0.8 22.9 7.8 1.3 0.9 10.0 0.1 0.0 13.1 66.6 1.5 1.7 1.4 1.3 0.7 9.4 0.8 19.8 5.7 2.6 9.8 0.1 2.3 35.2 0.0 24.4 0.2 43.6 32.2 0.1 0.6 2.6 18.8 4.4 0.1 1.4 0.9 0.2 0.4 75.4 16.8 1.0 4.8 0.2 2.1 10.1 3.9 9.7 2.0 6.1 3.1 8.5 63.2 16.6 29.5 17.5 4.9 1.1 0.1 0.1 9.8 2.7 1.2 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.8 51.6 98.0 71.7 45.5 34.0 53.4 82.3 79.2 106.4 72.2 80.9 82.9 93.3 173.1 85.9 29.7 1.1 16.2 48.6 29.5 42.1 4.8 7.2 21.2 339.0 38.6 27.5 14.7 0.0 8.7 0.5 0.1 7.9 36.1 2.2 3.0 29.5 76.6 0.0 143.1 3.9 19.1 1.5 52.4 1.1 3.8 30.4 8.8 71.7 38.5 13.0 42.1 5.3 0.0 6.1 15.3 19.3 11.9 169.6 16.7 10.6 32.8 1.3 14.1 0.0 15.6 52.0 17.0 0.0 504.0 0.4 12.1 0.0 26.1 22.3 1.3 368.1 29.7 183.5 1.1 1.9 5.7 11.8 1.9 4.1 20.7 0.2 17.3 RUFY4 "FLJ46536, ZFYVE31" ENSG00000188282 "RUN and FYVE domain containing 4" Q6ZNE9 2 218034960-218090581 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;lymphoid tissue: 2.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Langerhans cells: 4.0;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "Karpas-707: 10.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA037980 Uncertain NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA037980: AB_10672501" "unprognostic (1.27e-3)" "unprognostic (4.60e-3)" "unprognostic (9.39e-3)" "unprognostic (6.79e-2)" "unprognostic (5.92e-2)" "unprognostic (6.57e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-2)" "unprognostic (1.31e-3)" "unprognostic (1.50e-1)" "unprognostic (6.09e-2)" "unprognostic (1.55e-1)" "unprognostic (2.41e-14)" "unprognostic (1.36e-2)" "unprognostic (1.13e-3)" "unprognostic (3.45e-1)" "unprognostic (1.43e-5)" 0.1 0.2 0.5 0.9 0.6 0.8 0.1 0.4 1.8 0.1 0.4 0.2 0.7 0.0 0.0 0.4 0.2 0.5 0.0 0.9 0.4 0.1 0.2 0.4 1.1 0.4 0.4 0.1 0.0 0.0 0.1 0.0 0.4 1.1 0.5 0.1 0.5 0.1 0.0 0.3 0.7 0.0 0.5 2.2 0.6 0.1 0.4 1.7 0.1 0.0 0.8 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.4 1.8 0.9 0.4 0.4 0.4 0.4 0.5 0.4 0.4 0.0 0.0 0.0 2.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 9.5 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.3 4.0 0.3 0.0 0.9 0.0 1.0 2.0 0.0 0.0 13.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 40.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.1;dendritic cells: 5.2;granulocytes: 2.5;NK-cells: 11.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1472.7" "Lineage enriched" "Detected in many" 62 "granulocytes: 1472.7" "Cell line enriched" "Detected in single" 26 "HMC-1: 5.8" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" 13.2 0.5 0.3 25.1 0.5 9.5 0.4 0.3 1.7 0.7 0.5 0.4 0.2 0.2 0.0 1.6 2.9 4.1 1.8 0.3 0.3 0.5 2.0 9.7 0.3 0.4 0.4 0.1 1.5 0.3 0.2 2.6 1.2 0.3 0.2 0.0 0.5 0.1 0.4 0.3 0.6 1.8 0.3 40.5 0.9 0.2 0.5 1.8 0.4 12.0 0.6 5.6 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 2.3 2.9 23.7 0.8 0.3 0.2 2.1 6.1 0.7 0.1 0.4 8.7 1472.7 1.5 3.2 0.9 0.3 8.3 0.3 0.5 0.3 1.7 0.3 0.3 0.4 0.4 1.2 0.3 0.5 0.3 0.0 0.0 5.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.7 0.0 0.0 0.2 0.0 11.3 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 ARPC2 "ARC34, p34-Arc" ENSG00000163466 "Actin related protein 2/3 complex subunit 2" O15144 2 218217141-218254356 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001994, HPA008352, HPA052703" Approved Supported Nucleoplasm NA NA 6600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 3: Monocytes - Immune response regulation" Nucleoplasm "CAB001994: , HPA008352: AB_1854887, HPA052703: " "unprognostic (7.42e-2)" "unprognostic (4.07e-1)" "unprognostic (1.50e-1)" "unprognostic (3.28e-3)" "unprognostic (2.77e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.63e-5)" "unprognostic (3.23e-2)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (1.07e-7)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (7.41e-2)" 205.4 121.8 114.0 361.4 125.6 544.1 163.5 109.4 130.8 163.1 117.4 252.8 200.3 153.3 161.8 460.5 146.3 211.3 167.3 135.2 123.1 155.0 152.8 259.7 505.2 115.1 114.7 121.3 122.1 115.4 94.7 295.0 116.4 132.1 274.8 77.4 163.6 176.0 385.3 293.4 226.5 291.2 117.8 294.6 251.5 149.7 118.2 298.3 115.3 250.8 626.0 402.0 231.7 125.4 438.3 188.3 264.1 198.0 346.6 463.6 489.4 680.5 640.7 551.2 549.5 588.6 452.0 358.6 347.6 764.7 396.8 492.3 362.6 985.4 645.4 284.2 296.5 362.1 279.0 325.8 386.8 764.2 968.9 310.2 784.1 552.0 454.6 515.1 731.3 294.1 179.5 681.4 858.6 304.3 416.8 888.6 310.8 500.8 201.1 307.2 235.0 488.7 556.8 787.8 156.3 278.8 246.7 265.8 590.0 544.4 192.7 689.2 642.1 709.5 268.1 321.9 507.8 359.8 418.8 624.7 515.1 472.9 548.2 1728.0 1318.5 1975.5 930.7 1773.7 626.1 785.9 720.7 913.6 1330.1 658.5 505.7 750.0 2200.3 698.9 2060.4 734.3 1039.0 2503.2 114.0 125.6 109.4 130.8 135.2 123.1 115.1 114.7 116.4 117.8 118.2 125.4 334.8 285.2 326.6 21.2 506.7 928.5 691.0 1140.2 425.2 89.8 150.3 189.7 145.3 200.1 465.4 172.9 56.3 944.5 902.3 595.0 342.4 585.8 604.0 220.6 288.5 363.5 319.7 144.9 48.5 658.7 1509.4 301.7 242.6 222.4 414.5 600.6 281.3 98.4 1094.0 58.9 33.1 329.4 364.2 779.9 1321.0 759.3 214.0 896.1 414.4 53.4 1721.9 175.3 1336.7 30.7 33.7 919.8 604.5 326.5 529.9 762.7 510.9 342.8 249.6 95.3 302.4 131.6 571.2 324.4 227.9 645.2 970.6 1045.8 694.1 285.6 337.6 1126.5 GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.9;breast: 17.8;gallbladder: 17.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 20.3;Enteroendocrine cells: 46.0;Hofbauer cells: 16.3;Kupffer cells: 50.6;Macrophages: 19.9;monocytes: 45.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "classical monocyte: 288.1;intermediate monocyte: 712.0;non-classical monocyte: 695.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.0" "Cell line enhanced" "Detected in some" "ASC diff: 1.1;HHSteC: 1.7;U-937: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA062890 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" 31.9 1.6 0.1 2.7 0.2 2.2 17.8 0.4 0.7 0.6 0.2 3.8 1.0 0.9 0.0 0.5 1.2 17.3 5.1 0.2 0.1 5.3 1.9 2.2 0.8 0.1 0.1 1.8 1.7 0.0 0.8 3.9 0.1 1.1 0.5 0.0 0.8 0.3 0.5 1.4 4.9 10.1 0.1 7.5 6.4 2.4 0.3 0.4 1.7 0.7 0.2 4.8 0.8 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 1.7 0.1 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.9 0.8 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 1.9 0.1 0.6 288.1 0.4 0.7 712.0 0.7 0.2 0.5 0.7 140.2 0.7 0.6 0.4 6.5 0.5 695.6 6.0 0.9 156.5 0.1 0.2 0.4 0.7 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 6.2 0.0 3.4 0.0 1.1 0.3 0.2 0.2 0.0 0.0 0.1 0.3 0.5 1.5 0.1 3.7 0.0 0.5 1.8 0.2 11.7 0.2 8.2 1.0 20.3 1.5 46.0 0.0 0.0 0.5 4.5 2.8 6.6 0.8 1.3 6.2 1.8 0.0 16.3 0.0 0.0 2.7 0.0 50.6 1.2 1.9 3.4 19.9 0.0 1.9 45.3 0.0 0.0 0.0 0.0 0.5 1.5 2.6 0.3 0.3 0.4 0.2 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.4 1.6 0.8 0.1 0.2 0.4 AAMP ENSG00000127837 "Angio associated migratory cell protein" Q13685 2 218264129-218270178 "Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017717, HPA031868" Approved Supported Microtubules,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Microtubules Cytosol "CAB017717: , HPA031868: AB_2674078" "unprognostic (1.57e-1)" "unprognostic (6.12e-2)" "unprognostic (8.11e-3)" "prognostic unfavorable (1.62e-4)" "unprognostic (1.39e-2)" "unprognostic (5.04e-2)" "prognostic unfavorable (4.94e-7)" "unprognostic (8.94e-2)" "unprognostic (7.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (4.22e-2)" "unprognostic (5.51e-2)" "unprognostic (1.23e-3)" "unprognostic (5.26e-2)" "unprognostic (1.92e-1)" "unprognostic (9.09e-2)" 66.5 66.4 65.0 46.2 66.1 27.5 65.2 67.1 80.1 62.6 63.2 76.3 62.8 61.7 43.8 75.1 60.8 56.1 65.4 65.7 67.2 60.2 77.5 46.6 47.8 69.2 66.6 79.8 70.7 72.7 62.1 54.9 66.4 58.0 58.0 38.4 66.9 58.7 90.4 76.6 61.7 50.7 67.5 53.0 86.9 53.8 67.1 54.0 66.6 62.0 52.6 70.0 57.4 70.3 126.1 104.6 75.1 102.2 111.9 75.7 146.0 89.6 136.3 167.1 124.5 226.2 100.1 64.6 121.8 112.6 158.8 94.3 150.7 133.4 129.3 103.5 200.9 147.4 108.2 237.4 158.9 139.3 92.4 97.8 152.7 172.2 149.7 99.7 97.6 124.3 202.6 82.4 108.9 198.0 112.4 234.9 121.0 182.4 75.4 90.6 97.5 105.8 100.3 160.5 96.2 92.9 59.4 128.7 134.7 119.1 99.1 104.6 84.7 110.2 82.3 81.2 106.8 105.7 198.1 108.4 111.0 88.6 77.4 75.9 166.2 60.3 101.1 209.2 105.1 100.3 90.1 94.9 191.4 105.7 111.1 100.7 26.2 114.9 210.6 114.1 109.3 179.4 65.0 66.1 67.1 80.1 65.7 67.2 69.2 66.6 66.4 67.5 67.1 70.3 57.8 41.7 35.2 11.4 50.4 90.5 86.1 122.9 66.0 47.7 50.7 45.2 35.5 41.5 74.0 42.3 12.5 160.0 42.2 74.3 103.7 95.7 3.5 33.5 46.4 50.6 75.5 34.0 11.5 95.4 130.3 63.4 80.5 38.2 34.8 57.6 42.5 46.2 91.9 63.9 12.9 89.9 93.6 37.0 65.3 8.8 83.3 38.5 62.2 5.6 64.8 80.2 41.2 8.0 10.5 86.6 72.0 74.9 51.2 116.0 99.5 85.3 47.4 37.1 65.7 38.4 86.5 72.0 53.3 70.2 97.3 202.6 44.4 62.5 103.5 119.9 PNKD "BRP17, DKFZp564N1362, DYT8, FKSG19, FPD1, KIAA1184, KIPP1184, MGC31943, MR-1, MR-1S, PDC, PKND1, TAHCCP2" ENSG00000127838 "PNKD metallo-beta-lactamase domain containing" Q8N490 2 218270392-218346793 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 508.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010134, HPA017068" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA010134: AB_1079645, HPA017068: AB_1855495" "unprognostic (3.15e-3)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (1.89e-2)" "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (3.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (7.51e-2)" "unprognostic (3.29e-1)" "unprognostic (7.67e-2)" "prognostic unfavorable (5.13e-5)" "unprognostic (7.98e-2)" "unprognostic (2.17e-1)" "unprognostic (9.61e-2)" "unprognostic (1.44e-3)" 50.9 88.9 127.6 33.3 134.7 35.4 49.7 131.2 168.4 62.8 129.3 74.7 40.6 45.6 77.3 40.5 60.6 41.6 98.4 127.8 137.5 106.5 191.5 55.5 40.9 133.9 130.9 47.1 46.1 93.4 49.5 46.9 134.1 87.4 54.7 26.7 60.6 55.3 85.1 44.9 51.1 36.4 128.7 58.7 81.6 45.6 137.8 45.8 90.0 93.6 37.6 64.2 45.4 134.7 53.2 68.3 49.1 77.0 72.2 60.6 90.0 32.7 70.3 76.1 85.0 112.9 51.2 61.7 63.7 55.0 83.5 53.6 95.4 61.4 52.9 128.0 119.4 90.0 119.5 169.4 78.7 58.9 38.6 83.0 59.8 51.9 15.0 51.0 83.2 48.0 67.8 78.3 68.4 152.2 77.6 139.5 49.0 121.3 69.3 75.1 49.5 51.8 88.3 79.2 47.4 39.9 23.6 156.9 94.6 52.0 52.4 56.4 51.5 31.4 53.7 37.5 45.5 32.4 35.7 69.0 79.9 95.8 38.8 142.4 111.4 151.9 97.7 114.3 94.2 223.1 105.7 117.7 106.4 187.2 116.4 111.2 31.3 136.2 109.4 99.0 150.0 132.2 127.6 134.7 131.2 168.4 127.8 137.5 133.9 130.9 134.1 128.7 137.8 134.7 84.5 70.5 91.2 30.0 58.2 55.2 91.5 179.2 82.6 54.5 130.1 162.4 154.5 128.7 127.8 196.8 6.2 172.9 48.2 292.0 508.7 70.6 13.5 125.9 116.5 66.9 121.3 56.3 44.9 49.8 105.3 88.5 99.9 114.1 57.1 97.0 83.2 250.4 136.7 35.3 47.4 186.3 187.2 85.3 59.6 16.5 103.2 66.2 136.9 20.6 79.6 168.8 51.5 19.6 32.8 37.7 143.6 124.1 74.6 93.4 162.7 326.7 148.5 41.6 92.1 60.0 128.6 42.5 50.6 113.9 62.4 77.3 52.5 97.2 228.1 117.5 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 CATIP "C2orf62, MGC50811" ENSG00000158428 "Ciliogenesis associated TTC17 interacting protein" Q7Z7H3 2 218356857-218368099 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 20.0;testis: 7.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 11.7;Early spermatids: 13.6;Endometrial ciliated cells: 36.1;Late spermatids: 18.6;Proximal tubular cells: 11.3;Spermatocytes: 10.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "BEWO: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA044818 Supported NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" "HPA044818: AB_10959301" "unprognostic (7.11e-3)" "unprognostic (2.37e-1)" "unprognostic (3.95e-2)" "unprognostic (1.70e-3)" "unprognostic (3.20e-2)" "unprognostic (1.58e-1)" "unprognostic (1.35e-1)" "unprognostic (2.40e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-2)" "unprognostic (1.69e-2)" "unprognostic (3.44e-1)" "unprognostic (1.95e-3)" "unprognostic (1.46e-1)" "unprognostic (2.72e-1)" "unprognostic (9.93e-2)" "unprognostic (1.19e-1)" 0.1 0.1 0.9 0.0 0.9 0.1 0.0 0.7 0.5 1.3 6.0 0.0 0.0 0.4 4.9 0.0 20.0 0.3 0.0 0.9 1.4 3.4 0.0 2.2 0.0 2.5 3.4 0.1 1.1 1.8 1.3 0.8 2.0 1.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 2.5 0.2 0.1 7.3 1.2 0.0 3.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.9 0.7 0.5 0.9 1.4 2.5 3.4 2.0 2.5 1.2 1.5 0.1 0.0 0.5 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.7 2.8 0.0 5.5 0.0 2.2 0.0 0.0 11.7 1.4 13.6 36.1 0.4 0.2 0.0 0.0 0.9 0.2 1.3 0.1 1.1 0.8 0.0 0.1 0.7 0.1 1.3 0.0 0.6 0.0 0.0 2.7 0.0 18.6 0.6 1.8 0.0 1.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 11.3 0.7 0.1 0.0 0.2 0.2 10.2 0.1 0.0 0.0 4.7 0.1 0.3 0.0 0.1 SLC11A1 "LSH, NRAMP, NRAMP1" ENSG00000018280 "Solute carrier family 11 member 1" P49279 2 218382029-218396894 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 78.6;lymphoid tissue: 46.6" "Cell type enhanced" "Detected in many" "Hofbauer cells: 108.0;Kupffer cells: 166.8;Macrophages: 209.4;monocytes: 101.2" "Cancer enhanced" "Detected in many" "glioma: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 6.1;intermediate monocyte: 4.5;myeloid DC: 1.9;neutrophil: 4.1;non-classical monocyte: 6.0" "Group enriched" "Detected in many" 11 "dendritic cells: 1.9;granulocytes: 4.1;monocytes: 6.1" "Cell line enhanced" "Detected in some" "HEL: 1.2;HMC-1: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA029590, HPA050378, HPA068540" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Mitochondria Nucleoli "HPA029590: AB_10794613, HPA050378: , HPA068540: " "unprognostic (2.64e-1)" "unprognostic (3.05e-2)" "unprognostic (1.46e-2)" "unprognostic (2.34e-2)" "unprognostic (1.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.04e-3)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (1.58e-2)" "unprognostic (7.29e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (2.58e-8)" "unprognostic (9.55e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-2)" "unprognostic (1.08e-2)" 14.1 8.5 3.5 7.1 4.3 6.7 4.9 3.9 11.1 2.7 4.7 3.5 0.2 2.2 0.1 1.6 7.4 1.0 8.0 3.3 5.0 3.4 5.1 78.6 0.2 7.4 5.2 1.7 3.2 0.3 3.1 2.7 6.9 3.2 0.0 0.6 3.2 0.1 1.7 1.5 2.2 1.9 5.2 46.6 3.0 0.9 17.3 0.3 2.7 1.3 0.0 7.2 2.4 7.4 0.1 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 1.2 0.2 0.2 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.2 0.0 0.4 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 6.1 0.6 0.3 4.5 0.2 0.1 0.2 0.1 1.9 0.2 0.3 0.2 4.1 0.2 6.0 0.2 0.2 2.0 3.5 4.3 3.9 11.1 3.3 5.0 7.4 5.2 6.9 5.2 17.3 7.4 1.5 22.4 38.5 1.6 4.1 0.9 4.3 1.9 1.2 3.1 4.5 4.6 8.6 2.8 13.8 9.2 0.0 1.8 3.1 1.8 9.8 1.3 1.8 6.1 2.3 17.0 1.2 1.7 1.3 2.1 7.8 5.8 2.0 2.8 25.3 0.9 6.8 7.3 108.0 1.7 0.9 4.0 6.1 166.8 6.3 0.5 2.1 209.4 1.8 4.7 101.2 12.9 10.3 0.5 1.4 0.4 1.6 0.7 5.6 3.9 2.5 11.7 11.0 3.3 19.7 2.9 4.2 0.8 1.8 2.1 1.0 8.1 6.7 3.3 2.9 3.3 CTDSP1 "NLIIF, SCP1" ENSG00000144579 "CTD small phosphatase 1" Q9GZU7 2 218398256-218405941 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 184.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062654 Supported Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA062654: AB_2684819" "unprognostic (1.97e-2)" "unprognostic (4.02e-2)" "unprognostic (1.67e-3)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-2)" "unprognostic (3.90e-2)" "unprognostic (8.69e-2)" "unprognostic (2.98e-1)" "unprognostic (6.38e-2)" "unprognostic (3.70e-1)" "unprognostic (1.79e-1)" "unprognostic (2.58e-1)" "unprognostic (6.67e-2)" "unprognostic (2.62e-1)" "unprognostic (7.01e-2)" "unprognostic (1.57e-1)" 84.5 55.4 42.1 43.0 47.8 53.1 76.5 41.6 42.2 82.4 40.6 72.2 56.7 80.2 31.9 71.8 74.3 46.7 79.4 36.8 38.8 83.2 118.6 74.5 49.2 55.6 47.0 82.3 79.1 56.9 28.4 77.7 44.6 104.6 44.7 8.7 65.3 57.2 60.0 71.4 75.9 48.4 45.3 92.7 88.3 16.9 45.5 48.0 78.9 53.7 45.4 82.6 70.4 43.2 29.8 37.8 21.8 71.9 58.1 53.8 80.0 38.9 56.2 37.2 32.0 49.7 72.7 18.0 33.0 69.8 25.3 59.1 32.4 47.2 19.0 63.8 25.5 68.3 48.6 67.0 69.4 42.9 89.3 61.5 56.7 28.3 31.7 58.3 55.5 27.5 56.5 62.6 39.9 84.0 37.5 122.1 15.5 47.6 37.8 51.4 30.8 39.2 47.7 36.6 14.5 36.4 34.4 72.9 38.6 27.4 40.8 101.1 48.5 58.7 35.0 45.4 17.4 40.1 28.1 42.6 52.3 39.7 33.2 54.2 30.4 74.1 24.3 24.7 15.5 7.8 14.7 15.8 15.9 7.2 9.3 12.4 56.4 17.3 26.3 5.4 13.8 21.2 42.1 47.8 41.6 42.2 36.8 38.8 55.6 47.0 44.6 45.3 45.5 43.2 65.0 44.8 40.0 15.0 43.0 27.3 29.1 24.7 37.5 14.6 34.8 34.5 35.1 58.6 23.7 31.3 2.1 42.7 70.5 95.0 33.2 36.6 1.9 15.1 35.1 43.4 21.7 52.6 0.7 42.7 43.3 44.7 45.3 27.7 18.3 23.0 67.5 57.3 39.3 6.7 1.0 53.5 12.2 83.2 28.1 4.6 59.4 59.9 33.8 14.0 56.9 55.6 184.4 13.0 12.9 38.5 43.1 44.0 35.7 39.8 85.1 51.1 10.0 28.0 26.3 36.0 44.8 1.7 8.7 37.8 20.3 54.3 55.1 29.4 41.5 30.2 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 USP37 KIAA1594 ENSG00000135913 "Ubiquitin specific peptidase 37" Q86T82 2 218450251-218568351 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 119.4;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045160 Approved Approved Nucleoplasm,Nucleoli NA Yes "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nucleoli" "HPA045160: AB_10795620" "unprognostic (7.00e-2)" "unprognostic (2.29e-1)" "unprognostic (8.83e-2)" "unprognostic (9.19e-4)" "unprognostic (1.83e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.66e-3)" "unprognostic (1.17e-1)" "unprognostic (3.78e-3)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.87e-1)" "unprognostic (6.69e-2)" "unprognostic (6.41e-3)" 2.7 4.1 3.5 4.4 4.7 11.8 4.7 8.5 4.9 3.6 1.9 3.0 2.9 4.2 7.5 3.9 3.3 3.5 2.3 3.3 4.0 2.9 3.8 3.0 6.0 3.8 4.0 5.9 3.0 4.0 1.4 4.0 4.0 3.6 3.5 9.1 3.9 3.0 2.9 3.9 3.3 3.2 2.5 3.8 3.4 12.7 3.4 6.3 5.0 4.2 4.9 3.6 2.2 8.3 9.6 6.9 14.2 11.0 3.6 4.4 12.1 7.1 5.1 12.2 13.6 13.1 7.4 8.7 7.5 5.6 9.3 8.9 15.7 8.0 13.4 12.0 8.3 23.5 13.6 8.7 4.1 15.6 11.3 2.4 4.7 12.9 9.2 4.5 5.3 15.0 17.3 16.2 7.8 7.2 20.1 10.6 12.2 6.2 5.9 16.0 21.3 8.0 4.2 11.2 15.5 8.4 11.5 5.6 7.2 13.6 6.4 10.8 6.8 13.7 12.0 7.7 9.5 11.0 10.4 17.6 7.4 11.2 9.5 4.2 2.0 3.8 3.1 2.3 3.2 2.5 2.6 2.7 2.1 3.2 4.0 2.6 1.6 3.2 2.2 2.9 3.6 1.2 3.5 4.7 8.5 4.9 3.3 4.0 3.8 4.0 4.0 2.5 3.4 8.3 12.8 0.0 11.0 34.3 16.5 19.5 7.0 7.1 22.2 14.7 14.4 10.2 4.9 4.3 9.6 7.3 27.1 8.4 13.4 5.5 0.0 5.8 119.4 13.3 11.8 14.2 10.3 16.6 47.4 2.3 6.6 13.2 9.2 16.4 5.1 16.2 12.5 11.0 7.8 15.2 40.0 8.9 4.1 8.5 22.9 145.5 9.9 17.2 21.4 27.2 10.2 9.1 10.3 35.2 60.5 4.9 7.4 9.8 14.6 12.1 7.1 4.2 11.1 19.9 6.6 12.7 21.6 60.8 31.4 13.6 20.6 7.3 19.7 10.9 7.6 7.1 CNOT9 "CAF40, CT129, RCD1, RCD1+, RQCD1" ENSG00000144580 "CCR4-NOT transcription complex subunit 9" Q92600 2 218568580-218597080 "Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046622 Approved Approved "Cytoplasmic bodies" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Cytoplasmic bodies" "HPA046622: AB_10962694" "unprognostic (7.70e-2)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-2)" "prognostic unfavorable (8.41e-9)" "unprognostic (8.08e-3)" "unprognostic (1.91e-3)" "unprognostic (1.53e-2)" "unprognostic (7.02e-2)" "unprognostic (6.89e-2)" "prognostic unfavorable (4.69e-9)" "unprognostic (1.87e-2)" "unprognostic (2.38e-2)" "unprognostic (2.05e-1)" "unprognostic (4.67e-2)" 17.2 21.9 18.3 26.0 19.7 40.2 16.6 20.8 19.4 17.8 18.9 17.7 18.1 17.6 19.4 21.4 18.8 16.1 20.1 18.7 19.4 16.3 21.0 18.2 31.3 18.6 19.2 18.7 15.8 21.0 25.2 18.0 18.6 18.4 22.6 26.1 15.1 15.0 22.4 20.5 17.3 20.2 19.4 22.6 17.1 27.0 18.9 33.6 15.4 17.1 36.2 21.8 17.6 22.1 49.9 38.2 62.2 82.2 35.2 33.8 79.8 55.5 57.4 69.6 67.4 68.2 40.4 55.4 33.7 64.3 60.9 57.2 88.1 61.6 81.4 79.8 55.6 110.6 72.1 81.1 48.9 120.2 61.7 31.0 48.5 73.1 74.2 32.7 53.1 74.0 67.1 121.1 56.3 40.0 117.2 72.8 94.5 38.4 60.4 97.8 88.7 57.1 37.1 71.5 79.2 64.8 54.5 47.5 52.2 59.1 38.1 66.5 43.2 75.5 55.8 55.3 69.0 57.6 62.6 128.3 53.7 73.1 55.0 36.9 25.6 29.1 41.5 31.7 36.4 29.9 34.0 35.4 30.4 26.6 31.8 35.0 10.5 35.5 34.0 35.1 30.8 37.9 18.3 19.7 20.8 19.4 18.7 19.4 18.6 19.2 18.6 19.4 18.9 22.1 22.1 22.4 20.7 0.0 10.0 0.0 0.0 0.0 0.0 0.0 20.4 15.1 0.0 0.0 9.9 12.9 0.0 28.4 27.1 0.0 27.4 21.2 0.0 32.2 21.2 10.3 0.0 0.0 0.0 20.7 40.7 10.9 0.0 22.4 16.4 18.9 0.0 0.0 28.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 20.7 0.0 0.0 0.0 0.0 25.6 0.0 0.0 7.0 0.0 0.0 16.1 10.2 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 28.3 11.0 16.9 0.0 0.0 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607855-218637184 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 166.0;skeletal muscle: 114.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 139.9;Cone photoreceptor cells: 246.0;Rod photoreceptor cells: 176.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SH-SY5Y: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.5 2.7 4.5 0.2 4.4 0.0 1.3 4.5 7.2 1.4 3.5 15.6 0.6 0.6 0.3 4.8 0.6 0.4 1.1 4.5 4.6 10.7 0.6 0.6 0.1 5.6 5.1 0.7 0.5 1.7 9.6 0.2 4.9 4.4 1.7 166.0 2.3 0.3 114.0 1.0 3.3 1.3 4.2 0.3 6.9 9.8 5.0 0.1 1.6 30.4 0.1 20.5 2.0 4.7 0.0 0.9 1.2 0.0 0.3 1.2 1.1 0.0 2.5 0.4 1.3 0.0 0.1 0.0 1.5 0.4 0.4 0.1 0.0 1.5 0.3 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 2.8 0.1 1.9 0.5 4.2 2.8 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.1 4.3 0.0 1.8 20.2 0.3 0.1 0.1 0.2 2.1 0.0 4.5 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 4.4 4.5 7.2 4.5 4.6 5.6 5.1 4.9 4.2 5.0 4.7 0.3 0.0 1.1 7.8 0.1 0.5 0.3 0.9 3.4 139.9 1.5 0.9 1.0 0.0 0.1 0.0 246.0 0.1 0.1 0.0 0.0 0.1 21.4 0.6 0.4 1.5 0.0 0.0 6.7 0.0 13.5 0.7 0.0 1.0 0.0 0.1 0.7 0.0 0.6 8.4 4.9 0.1 0.0 0.0 0.4 33.8 0.3 0.2 0.0 0.0 0.1 9.1 0.0 2.0 2.3 0.7 0.0 0.0 0.0 0.1 0.0 2.2 0.2 176.9 0.0 6.1 1.8 3.6 1.2 0.6 0.1 0.8 0.1 0.0 0.1 0.2 ZNF142 "KIAA0236, pHZ-49" ENSG00000115568 "Zinc finger protein 142" P52746 2 218633329-218659655 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049594 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 59: Non-specific - Translation" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoli fibrillar center" Nucleoplasm "HPA049594: AB_2680829" "unprognostic (2.17e-1)" "unprognostic (4.43e-1)" "unprognostic (8.20e-3)" "unprognostic (9.08e-2)" "unprognostic (3.54e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.35e-5)" "unprognostic (2.94e-1)" "unprognostic (1.01e-1)" "unprognostic (2.20e-2)" "unprognostic (9.63e-3)" "unprognostic (4.77e-2)" "unprognostic (1.83e-2)" "unprognostic (6.31e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-2)" "unprognostic (7.05e-2)" 6.0 5.7 5.0 5.0 5.5 8.0 6.0 5.5 6.9 6.4 1.2 8.0 2.6 7.5 2.5 6.7 6.7 3.6 7.0 5.5 3.6 6.3 4.5 5.4 5.3 4.5 3.9 6.2 7.5 4.9 8.3 3.2 4.2 6.8 3.1 6.4 6.3 4.3 10.3 7.0 6.5 4.9 2.6 7.3 7.0 4.8 4.7 6.0 6.9 6.6 4.9 7.3 5.8 5.1 6.3 9.7 9.0 10.7 8.5 6.3 8.5 7.1 4.2 9.7 7.4 19.3 5.0 8.3 6.1 6.4 8.1 11.4 17.6 11.7 6.6 12.0 16.5 12.9 20.7 12.3 6.8 16.8 11.8 4.3 11.0 11.5 11.3 5.3 8.2 9.2 17.0 15.7 5.0 13.7 11.7 9.6 11.8 3.9 8.8 17.7 5.1 8.1 7.3 11.3 12.3 9.3 5.3 10.4 4.0 8.5 6.0 6.1 12.2 9.2 9.7 7.8 11.0 10.5 7.1 13.4 5.9 7.9 9.5 0.9 0.7 0.8 1.0 0.1 0.4 0.7 0.6 0.6 0.6 0.3 0.7 0.5 0.4 0.3 0.2 0.8 0.6 0.6 5.0 5.5 5.5 6.9 5.5 3.6 4.5 3.9 4.2 2.6 4.7 5.1 3.5 3.2 0.5 4.9 6.0 5.9 2.0 1.7 5.7 3.5 3.8 3.4 5.3 4.3 2.7 3.7 6.2 2.2 4.0 4.1 0.0 3.2 2.7 2.7 4.3 3.2 0.0 2.1 7.0 3.8 2.2 3.8 6.6 5.2 1.3 5.2 4.2 3.1 3.0 1.7 6.7 3.0 4.1 4.7 3.2 4.8 3.7 4.1 3.6 4.7 3.1 2.3 8.2 3.0 6.7 4.1 3.5 3.8 8.5 2.8 3.4 2.2 1.0 2.7 6.6 3.9 2.9 5.5 5.5 6.6 6.1 1.1 6.3 4.1 4.3 2.3 BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chaperone "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037700, HPA037701" Supported NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 35: Non-specific - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA037700: AB_10794619, HPA037701: AB_10805235" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (6.28e-2)" "unprognostic (4.99e-2)" "unprognostic (6.44e-2)" "unprognostic (4.31e-1)" "unprognostic (4.25e-2)" "unprognostic (2.45e-1)" "unprognostic (8.38e-2)" "unprognostic (1.83e-2)" "unprognostic (1.21e-2)" "unprognostic (6.02e-2)" "unprognostic (3.47e-3)" "unprognostic (1.59e-1)" "unprognostic (3.15e-2)" "unprognostic (8.38e-2)" "prognostic favorable (3.31e-4)" 19.9 29.3 24.0 11.5 24.8 12.4 21.3 25.0 25.9 24.9 23.9 22.6 15.9 21.6 14.3 28.2 20.3 10.9 40.8 24.3 25.0 30.5 39.9 16.3 15.5 25.2 25.4 25.2 41.2 17.8 17.4 11.8 26.1 27.2 16.5 13.5 20.8 17.4 32.0 24.2 20.9 16.8 24.5 24.2 25.8 10.1 24.8 9.8 22.1 22.5 14.4 25.5 23.5 26.1 17.1 34.3 19.3 26.8 42.8 28.6 28.9 28.4 15.7 44.9 32.9 92.1 28.0 25.2 40.4 29.1 30.3 46.2 63.0 73.1 25.4 37.2 67.9 40.4 45.5 76.0 49.4 35.6 24.4 36.6 55.0 61.1 79.5 18.4 46.0 35.3 58.3 35.6 41.1 57.7 26.6 48.2 23.7 39.9 43.5 38.3 23.8 40.0 37.6 31.1 41.1 17.9 20.1 48.2 36.9 30.4 25.4 34.9 26.7 33.3 27.7 22.3 39.5 28.1 23.2 43.2 21.1 54.2 32.6 20.1 12.2 10.5 10.3 7.7 11.7 13.5 8.1 9.7 24.6 12.8 9.9 11.9 1.4 7.7 1.1 13.7 13.4 10.2 24.0 24.8 25.0 25.9 24.3 25.0 25.2 25.4 26.1 24.5 24.8 26.1 16.0 9.6 7.5 6.5 6.4 10.6 15.2 29.9 8.6 13.3 13.0 16.0 32.7 20.0 18.3 5.5 6.2 31.4 5.4 9.2 21.5 18.1 1.3 9.2 15.4 13.7 6.1 7.8 3.8 10.1 18.0 13.8 11.2 10.8 11.4 14.6 10.4 11.8 17.4 6.7 3.9 11.0 20.3 5.0 9.0 2.2 9.0 6.6 14.2 2.8 9.2 12.1 11.3 8.0 6.9 11.4 12.7 15.4 9.8 11.6 13.1 22.2 10.7 15.9 6.6 14.7 19.4 5.5 11.6 16.6 9.9 14.5 6.4 18.8 17.0 12.9 RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Nucleoplasm, Actin filaments" "HPA036420: AB_2675114, HPA036421: AB_10669604" "unprognostic (3.22e-2)" "unprognostic (7.85e-3)" "unprognostic (1.34e-2)" "unprognostic (2.29e-2)" "unprognostic (1.33e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.58e-4)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (3.46e-1)" "unprognostic (2.04e-3)" "unprognostic (8.82e-2)" "unprognostic (1.26e-3)" "unprognostic (2.50e-1)" "unprognostic (1.37e-1)" "unprognostic (2.44e-1)" "unprognostic (6.69e-2)" 10.9 11.4 18.5 8.9 18.6 7.3 10.9 18.3 21.0 12.2 17.1 12.0 6.2 12.7 15.8 11.7 12.4 10.8 13.9 18.6 19.7 10.4 11.1 10.4 14.5 18.4 18.4 14.5 11.5 15.1 11.4 11.4 19.0 11.8 8.2 7.0 11.0 13.9 15.0 14.5 7.9 13.6 18.5 10.3 9.4 14.3 19.2 15.1 14.1 17.1 11.9 14.0 9.7 19.0 18.8 20.4 22.1 24.6 27.6 17.5 20.4 27.3 43.5 58.0 53.6 32.4 13.2 11.6 17.6 42.3 35.2 19.5 22.1 33.9 31.0 16.4 27.3 22.7 21.3 34.6 33.6 19.3 20.6 33.9 30.9 55.5 44.7 21.4 31.0 40.9 27.4 24.3 41.1 45.3 20.6 20.4 32.9 16.2 23.4 23.2 15.5 15.9 36.3 21.8 19.5 23.8 18.1 17.2 28.4 21.9 20.6 25.6 26.6 40.2 20.5 19.2 31.1 23.7 13.7 23.5 33.4 19.1 25.7 58.6 21.5 32.6 26.0 21.3 24.8 25.7 25.7 27.2 17.1 30.4 29.0 23.2 17.1 30.5 25.2 15.0 25.9 24.8 18.5 18.6 18.3 21.0 18.6 19.7 18.4 18.4 19.0 18.5 19.2 19.0 4.2 0.0 0.5 5.2 7.8 6.2 4.8 16.3 6.8 7.7 3.4 3.7 4.0 10.0 8.9 1.8 8.4 12.3 4.5 7.4 15.6 12.3 16.8 6.3 8.1 7.6 1.2 2.1 6.2 12.9 9.7 7.5 9.7 4.8 7.0 5.9 8.9 7.1 13.2 5.0 5.8 5.5 8.2 5.0 4.0 5.3 7.2 5.5 8.8 2.8 8.9 7.9 9.2 3.5 4.9 12.7 9.6 12.8 8.5 3.8 7.2 14.8 8.2 5.0 26.3 5.6 9.2 19.3 12.8 5.9 6.8 10.0 8.0 8.5 6.1 3.6 STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Respiratory ciliated cells: 38.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA027409: AB_10600223, HPA027453: AB_10601893, HPA030058: AB_10601225" "unprognostic (8.11e-2)" "unprognostic (3.77e-1)" "unprognostic (3.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (5.20e-4)" "unprognostic (1.55e-1)" "unprognostic (5.83e-3)" "unprognostic (9.04e-2)" "unprognostic (1.38e-2)" "unprognostic (1.13e-2)" "unprognostic (3.52e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.99e-3)" 5.6 9.9 1.5 5.4 1.7 2.5 6.6 1.0 3.2 14.1 15.4 9.0 4.4 11.4 13.4 5.1 14.3 10.5 3.5 2.3 1.0 7.3 4.5 7.3 4.5 1.2 2.6 13.4 10.7 9.4 14.8 4.3 0.8 9.6 6.5 11.6 7.3 8.2 3.7 5.0 6.4 8.0 0.3 5.1 8.8 32.0 1.3 3.2 11.8 2.3 4.0 8.2 7.6 1.0 3.7 8.2 17.6 15.0 18.7 14.5 10.9 9.8 7.8 12.2 11.4 10.7 6.0 4.8 13.3 10.3 8.2 7.2 12.2 10.3 10.7 2.8 10.2 4.7 27.1 15.0 9.1 6.7 7.6 15.7 7.5 12.0 8.4 32.3 9.3 6.2 11.1 6.0 10.3 8.5 4.0 8.5 10.7 4.6 5.2 7.3 7.6 5.1 14.9 18.2 14.2 12.3 7.6 12.2 5.0 18.2 12.4 5.3 8.9 16.8 6.1 6.5 6.8 7.5 6.3 2.5 10.4 3.1 7.1 0.0 0.4 0.7 0.3 0.2 0.1 0.4 0.2 0.2 0.3 0.1 0.2 0.3 0.0 0.5 0.3 0.3 0.2 0.4 1.5 1.7 1.0 3.2 2.3 1.0 1.2 2.6 0.8 0.3 1.3 1.0 2.1 9.6 6.3 18.3 1.6 1.1 0.9 3.6 2.8 7.4 7.4 5.5 4.0 5.7 3.7 3.7 37.5 1.8 2.9 2.9 0.0 3.7 16.9 17.5 9.0 3.3 2.4 0.8 22.0 2.5 1.5 4.5 10.7 6.3 1.3 12.2 3.3 5.9 2.7 1.7 18.0 4.4 6.1 2.5 1.2 6.0 5.9 2.0 0.0 2.8 2.5 4.9 1.0 8.5 6.2 2.2 5.0 4.9 0.6 1.6 2.5 4.4 38.2 9.1 6.6 3.1 4.0 28.0 8.9 3.7 1.0 0.8 1.5 11.0 4.9 0.9 TTLL4 KIAA0173 ENSG00000135912 "Tubulin tyrosine ligase like 4" Q14679 2 218710835-218755416 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.4;Muller glia cells: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027091, HPA050252" Approved Approved Mitochondria NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 5: Muller glia cells - Visual perception" Mitochondria "HPA027091: AB_10601828, HPA050252: AB_2681064" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (4.64e-1)" "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (1.66e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (3.83e-3)" "unprognostic (2.96e-2)" "unprognostic (1.21e-1)" "unprognostic (7.52e-2)" "unprognostic (2.42e-2)" "prognostic unfavorable (6.63e-12)" "unprognostic (9.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.85e-1)" "unprognostic (5.29e-3)" 3.9 7.2 7.1 8.4 9.9 5.8 6.4 7.5 9.6 5.4 20.1 5.5 5.6 4.7 3.5 6.9 7.3 4.2 4.6 7.2 8.4 4.4 5.9 6.9 6.2 9.7 11.2 4.5 7.1 5.2 6.7 8.0 10.1 6.6 6.4 15.2 6.8 3.7 5.6 8.6 5.8 5.2 7.2 5.7 8.9 25.5 9.6 5.7 3.9 2.9 8.9 5.2 6.3 10.6 18.4 12.3 32.3 16.4 8.1 6.3 43.5 12.2 9.8 19.8 16.8 52.6 21.4 14.4 10.1 9.5 18.9 19.0 34.3 16.9 23.0 16.3 27.3 18.5 19.0 50.2 11.5 23.6 13.1 10.4 10.1 17.7 19.9 8.5 19.0 16.0 53.8 22.2 11.0 10.7 13.1 15.3 36.4 13.5 8.1 29.4 14.6 18.9 19.7 14.5 12.9 12.7 9.3 13.7 23.9 48.9 11.1 12.0 7.6 17.6 17.9 11.3 11.7 11.2 10.1 32.4 9.2 14.5 23.4 0.1 12.6 0.8 3.1 6.0 2.9 3.9 2.3 2.3 7.3 3.5 1.5 1.4 14.5 2.1 8.8 4.3 1.3 5.1 7.1 9.9 7.5 9.6 7.2 8.4 9.7 11.2 10.1 7.2 9.6 10.6 1.6 3.2 5.8 28.4 3.1 4.6 12.3 3.2 4.6 6.6 4.5 5.1 3.5 5.7 4.2 7.3 27.1 6.8 3.0 2.4 0.0 6.0 39.4 7.8 3.1 3.7 5.4 6.5 3.9 3.9 8.0 4.8 10.2 5.3 1.3 4.2 1.8 2.6 7.8 3.3 4.8 4.7 4.1 5.5 2.9 16.1 3.1 9.4 3.6 15.9 10.4 72.7 5.2 11.1 20.8 5.8 2.5 1.5 2.8 15.2 2.9 1.8 7.5 12.7 0.0 3.3 3.1 18.3 12.7 4.2 4.1 5.7 2.5 2.1 5.1 11.4 CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "liver: 594.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 404.3;Hofbauer cells: 148.9;Proximal enterocytes: 206.3" "Group enriched" "Detected in all" 4 "liver cancer: 176.9;melanoma: 85.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.5;neutrophil: 126.3" "Group enriched" "Detected in many" 21 "granulocytes: 126.3;monocytes: 151.5" "Cell line enhanced" "Detected in many" "Hep G2: 299.6;HSkMC: 54.7;RPTEC TERT1: 78.5;SK-MEL-30: 103.6;WM-115: 42.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Mitochondria Cytosol "HPA059155: AB_2683933" "prognostic favorable (1.05e-4)" "unprognostic (4.21e-2)" "unprognostic (2.34e-1)" "unprognostic (1.83e-3)" "unprognostic (3.71e-3)" "unprognostic (1.31e-2)" "prognostic favorable (8.62e-6)" "unprognostic (6.04e-2)" "unprognostic (1.73e-1)" "unprognostic (4.04e-1)" "unprognostic (1.25e-3)" "unprognostic (8.76e-3)" "unprognostic (1.09e-3)" "unprognostic (1.08e-1)" "unprognostic (7.51e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 23.1 50.3 45.2 15.7 59.0 1.3 21.8 57.0 59.3 27.6 75.6 27.6 77.8 19.8 11.6 11.9 34.0 19.1 30.7 42.2 49.3 46.4 594.4 71.7 24.6 63.0 56.1 32.6 8.3 18.5 29.6 6.2 62.7 41.8 20.7 22.5 40.4 29.5 37.9 17.5 81.9 13.2 50.6 13.0 13.8 12.6 58.8 23.6 12.6 49.2 28.0 24.3 23.2 69.2 0.2 0.0 2.7 0.2 4.6 3.3 0.4 1.9 11.7 3.9 7.8 13.7 0.8 0.0 4.3 7.6 0.2 0.1 0.0 0.0 1.7 1.4 1.0 0.0 0.4 299.6 16.2 0.4 0.3 54.7 0.5 0.1 0.0 12.8 5.9 0.0 0.3 0.1 8.3 0.0 0.0 0.2 2.3 0.3 0.5 0.1 2.4 0.5 78.5 0.2 0.2 0.2 0.1 0.0 103.6 2.4 1.6 2.2 5.9 0.0 0.2 0.1 6.0 0.0 0.0 0.1 0.1 0.3 42.9 0.0 151.5 0.4 0.2 17.1 0.3 0.7 0.2 0.5 6.5 0.0 0.1 0.0 126.3 0.0 1.2 0.8 0.0 44.1 45.2 59.0 57.0 59.3 42.2 49.3 63.0 56.1 62.7 50.6 58.8 69.2 10.6 3.2 28.9 33.6 0.9 5.2 52.4 8.5 21.6 15.3 12.7 18.8 5.1 17.2 11.3 3.7 27.1 0.7 0.5 37.0 9.8 12.1 1.0 12.6 4.3 10.3 24.5 8.4 2.2 12.0 0.7 35.4 2.6 14.8 2.5 1.9 19.6 404.3 148.9 10.1 3.9 20.0 4.1 18.2 5.1 1.0 47.5 104.3 49.8 15.0 92.4 28.7 0.0 26.7 108.5 9.7 44.0 26.7 0.0 43.3 206.3 76.9 21.4 14.1 0.0 12.8 7.2 0.7 0.1 3.2 3.1 1.2 2.3 1.2 30.3 20.4 PRKAG3 ENSG00000115592 "Protein kinase AMP-activated non-catalytic subunit gamma 3" Q9UGI9 2 218822383-218832086 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "skeletal muscle: 70.4;tongue: 17.9" "Cell type enhanced" "Detected in single" "Skeletal myocytes: 3.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (3.51e-1)" "unprognostic (4.41e-3)" "unprognostic (2.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.47e-2)" "unprognostic (1.80e-1)" "unprognostic (1.86e-3)" "unprognostic (7.74e-2)" "unprognostic (3.44e-2)" "unprognostic (5.85e-2)" "unprognostic (3.27e-1)" "unprognostic (9.04e-2)" "unprognostic (9.95e-2)" "unprognostic (1.49e-1)" "unprognostic (2.97e-1)" "unprognostic (7.69e-2)" 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.8 0.0 70.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 17.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 WNT6 ENSG00000115596 "Wnt family member 6" Q9Y6F9 2 218859805-218874233 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 92.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 8.7" "Region enhanced" "Detected in many" "basal ganglia: 10.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 34.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.7" HPA070759 Approved "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" "HPA070759: AB_2732164" "unprognostic (1.86e-2)" "unprognostic (6.03e-2)" "unprognostic (5.14e-2)" "unprognostic (2.06e-1)" "unprognostic (5.32e-2)" "unprognostic (7.34e-2)" "unprognostic (8.08e-3)" "unprognostic (4.73e-2)" "unprognostic (1.27e-2)" "unprognostic (1.19e-1)" "unprognostic (1.21e-2)" "unprognostic (2.66e-1)" "unprognostic (1.24e-3)" "unprognostic (5.26e-2)" "unprognostic (4.82e-2)" "unprognostic (1.55e-1)" "unprognostic (2.07e-1)" 3.5 0.6 1.1 0.1 10.0 0.0 3.5 0.3 4.2 4.3 0.5 7.4 0.1 2.4 0.0 1.3 3.2 0.0 3.4 0.9 0.8 1.1 0.3 0.3 0.1 1.0 1.1 3.1 0.8 0.0 2.0 2.0 1.1 3.1 0.0 0.1 1.1 0.1 1.1 2.6 2.8 0.0 0.5 7.2 2.7 3.6 2.5 0.0 1.1 0.0 0.1 1.9 3.7 0.2 0.0 0.0 0.0 1.2 0.0 0.0 34.4 0.0 0.0 0.0 0.0 3.3 0.5 0.0 3.7 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.0 5.0 1.7 0.0 0.0 3.7 0.1 4.7 0.0 0.0 2.7 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 1.1 10.0 0.3 4.2 0.9 0.8 1.0 1.1 1.1 0.5 2.5 0.2 2.5 0.0 0.0 0.0 1.6 0.5 21.0 1.1 0.6 3.5 1.4 8.5 0.6 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.0 0.1 3.4 0.4 3.1 5.9 0.0 0.0 0.2 0.0 1.6 2.0 0.0 0.1 0.0 0.4 2.5 0.0 0.8 1.7 0.1 0.0 0.0 0.0 0.3 4.5 0.0 0.3 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.4 3.1 5.5 0.0 0.0 0.0 2.0 92.1 0.3 15.5 16.9 0.3 0.2 0.1 0.7 0.2 0.1 0.0 1.3 WNT10A ENSG00000135925 "Wnt family member 10A" Q9GZT5 2 218880852-218899581 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant, Ectodermal dysplasia, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 7.0;skin 1: 8.9" "Cell type enhanced" "Detected in many" "B-cells: 12.2;Basal keratinocytes: 17.1;Basal respiratory cells: 15.5;Basal squamous epithelial cells: 30.1;Bipolar cells: 16.2;dendritic cells: 16.4;Plasma cells: 30.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 6.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 6.2" "Cell line enhanced" "Detected in some" "CAPAN-2: 50.8;HaCaT: 140.1;HDLM-2: 58.7;RPTEC TERT1: 29.2;U-266/70: 69.0" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Region enhanced" "Detected in single" "basal ganglia: 2.1" HPA013898 Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "HPA013898: AB_1858847" "unprognostic (2.99e-4)" "unprognostic (4.31e-2)" "unprognostic (8.55e-2)" "unprognostic (1.17e-3)" "unprognostic (2.87e-2)" "unprognostic (2.59e-1)" "unprognostic (1.62e-1)" "unprognostic (2.56e-2)" "unprognostic (1.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.23e-3)" "unprognostic (9.52e-2)" "unprognostic (6.64e-9)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (4.89e-3)" "unprognostic (1.82e-1)" 0.7 0.2 0.7 1.0 1.6 0.5 0.5 0.2 1.3 1.5 0.2 1.6 3.7 0.0 0.4 7.0 1.2 0.3 0.1 1.2 0.5 2.4 0.2 0.7 2.5 0.4 0.6 0.2 0.1 0.0 4.3 3.4 0.5 1.7 1.0 1.4 2.5 1.0 0.0 8.9 2.1 0.0 0.3 2.0 2.5 0.4 0.7 1.1 0.2 0.0 1.9 2.7 2.9 0.7 15.8 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 50.8 2.8 10.4 0.0 3.8 140.1 0.0 0.1 0.0 58.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 10.5 29.2 0.4 0.0 0.4 0.3 0.0 0.1 0.8 0.0 0.2 0.0 0.0 0.9 0.0 0.0 69.0 1.1 1.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.7 0.2 0.0 0.0 0.0 0.0 6.2 1.0 0.0 0.7 1.6 0.2 1.3 1.2 0.5 0.4 0.6 0.5 0.3 0.7 0.7 0.2 0.0 0.0 0.3 12.2 17.1 8.2 15.5 30.1 16.2 0.5 1.3 1.4 0.0 1.1 9.2 2.1 1.2 16.4 0.0 0.0 0.3 1.2 0.3 0.1 0.2 0.0 0.4 1.3 0.0 0.4 1.9 0.5 0.2 0.0 0.0 0.0 0.2 0.1 0.0 1.9 0.0 2.0 0.0 1.3 0.1 0.6 1.0 7.2 0.0 0.0 0.5 0.0 0.5 0.1 0.1 0.0 0.0 30.4 2.5 0.0 0.3 0.6 1.5 0.0 0.1 0.8 0.9 0.6 5.2 4.7 0.1 9.8 0.0 0.2 3.2 CDK5R2 "NCK5AI, P39, p39nck5ai" ENSG00000171450 "Cyclin dependent kinase 5 regulatory subunit 2" Q13319 2 218959666-218962155 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 52.2;pituitary gland: 35.2;retina: 26.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 78.8;Cone photoreceptor cells: 20.9;Enteroendocrine cells: 22.8;Excitatory neurons: 17.7;Horizontal cells: 15.2;Rod photoreceptor cells: 50.9" "Cancer enhanced" "Detected in some" "glioma: 3.9;pancreatic cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "SCLC-21H: 18.4;SH-SY5Y: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (1.96e-1)" "unprognostic (6.53e-2)" "unprognostic (3.85e-5)" "unprognostic (1.73e-6)" "unprognostic (3.67e-2)" "unprognostic (2.83e-4)" "unprognostic (1.27e-3)" "unprognostic (7.21e-2)" "unprognostic (1.78e-1)" "unprognostic (6.71e-3)" "unprognostic (3.53e-3)" "unprognostic (2.34e-10)" "unprognostic (1.54e-1)" "unprognostic (1.64e-4)" "unprognostic (6.46e-2)" 0.0 3.9 17.0 0.3 21.5 0.0 0.0 0.0 52.2 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 20.2 17.4 0.0 0.0 0.0 0.0 7.1 3.6 0.0 1.0 0.0 35.2 0.0 10.7 0.0 0.1 26.3 0.0 0.0 0.0 0.0 0.4 0.1 1.4 0.0 0.9 0.8 15.6 0.0 0.0 0.0 0.0 0.0 0.1 20.0 0.4 0.4 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 2.1 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 18.4 13.3 0.7 0.0 0.1 0.4 0.0 0.0 0.0 0.2 1.3 0.0 0.3 0.0 0.0 0.0 0.6 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 21.5 0.0 52.2 20.2 17.4 7.1 3.6 10.7 1.4 15.6 20.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 78.8 0.0 0.0 0.5 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 22.8 0.0 17.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.2 11.9 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 8.1 0.0 2.0 2.6 0.2 1.2 0.0 0.0 0.1 0.1 0.0 0.0 50.9 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 FEV Pet-1 ENSG00000163497 "FEV transcription factor, ETS family member" Q99581 2 218981087-218985184 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 70.8" "Cell type enriched" "Detected in some" 32 "Enteroendocrine cells: 744.9" "Group enriched" "Detected in some" 10 "pancreatic cancer: 3.0;prostate cancer: 9.9;stomach cancer: 2.4" "Group enriched" "Detected in many" 7 "midbrain: 70.8;pons: 20.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HMC-1: 35.5;SH-SY5Y: 43.8" "Region enhanced" "Detected in single" "midbrain: 1.9" "Group enriched" "Detected in some" 5 "midbrain: 4.8;pons: 2.7" HPA067679 Supported Supported "Nuclear speckles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nuclear speckles" "HPA067679: AB_2685884" "unprognostic (4.58e-1)" "unprognostic (1.60e-1)" "unprognostic (7.21e-2)" "prognostic favorable (4.85e-4)" "unprognostic (2.87e-1)" "unprognostic (3.96e-1)" "unprognostic (1.52e-1)" "unprognostic (2.15e-1)" 0.1 2.3 0.0 0.0 1.7 0.0 0.0 0.0 0.6 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 6.2 70.8 0.0 1.3 0.0 2.6 0.0 20.1 2.2 1.8 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 43.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.6 0.6 0.1 6.2 70.8 20.1 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 744.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 6.0 0.0 0.0 3.4 1.2 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.1 CRYBA2 ENSG00000163499 "Crystallin beta A2" P53672 2 218990189-218993422 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.1;pancreas: 16.6;pituitary gland: 13.7" "Cell type enriched" "Detected in some" 34 "Enteroendocrine cells: 860.9" "Cancer enriched" "Detected in some" 15 "pancreatic cancer: 16.0" "Region enhanced" "Detected in many" "midbrain: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "BEWO: 69.6" "Region enhanced" "Detected in some" "pons and medulla: 4.3" "Low region specificity" "Detected in some" HPA062293 Supported NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA062293: AB_2732680" "unprognostic (5.29e-2)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (4.19e-1)" "unprognostic (6.19e-2)" "unprognostic (1.77e-1)" "unprognostic (2.72e-1)" "unprognostic (1.66e-2)" "unprognostic (3.75e-1)" "prognostic favorable (7.62e-4)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.19e-1)" 0.3 3.5 0.5 0.0 1.0 0.0 0.0 0.7 0.8 0.0 0.3 2.1 2.8 0.0 0.2 0.2 0.0 0.0 0.1 0.5 0.9 0.2 0.0 0.0 0.0 2.0 11.1 0.0 16.6 1.4 13.7 0.0 5.0 0.8 2.2 0.2 0.1 0.0 0.1 0.2 2.7 0.0 0.4 0.0 4.5 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 69.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 2.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 1.9 0.1 0.2 0.1 0.1 1.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.7 0.8 0.5 0.9 2.0 11.1 5.0 0.4 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.5 0.4 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 3.8 0.0 0.0 0.1 860.9 0.0 0.1 1.3 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 25.0 0.0 0.0 0.4 10.0 0.0 0.1 1.8 0.0 0.0 0.1 0.0 0.0 0.0 7.5 17.5 0.0 0.0 1.0 3.9 0.0 0.0 0.9 0.0 0.0 0.0 0.6 4.5 0.0 0.3 0.3 0.1 0.0 1.7 0.0 CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;choroid plexus: 13.5;fallopian tube: 25.7;testis: 9.4" "Group enriched" "Detected in many" 4 "Early spermatids: 204.5;Late spermatids: 164.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.8" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" 0.0 0.1 2.3 0.0 2.1 0.0 0.1 1.0 1.0 1.3 13.5 0.1 0.0 0.5 1.8 0.0 25.7 0.4 0.0 2.6 2.8 0.4 0.0 2.7 0.0 8.4 12.1 0.0 0.3 0.1 3.5 0.0 6.2 0.1 0.2 9.2 0.1 0.1 0.0 0.0 0.4 0.0 6.1 0.0 0.3 9.4 2.4 0.0 0.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.0 1.0 2.6 2.8 8.4 12.1 6.2 6.1 2.4 3.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.8 7.7 8.8 0.0 4.3 6.8 0.0 12.5 0.0 0.1 1.1 0.0 0.6 204.5 45.1 0.5 0.2 29.1 0.0 0.0 1.5 0.0 0.2 2.0 1.8 0.0 0.2 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.0 0.0 164.3 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.8 0.7 0.0 1.1 1.9 1.1 29.2 19.5 0.0 0.1 0.0 14.4 5.7 0.0 0.0 0.0 0.2 0.1 5.1 0.1 IHH "BDA1, HHG2" ENSG00000163501 "Indian hedgehog signaling molecule" Q14623 2 219054424-219060921 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Developmental protein, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 14.0;intestine: 22.3;stomach 1: 15.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 31.5;Enteroendocrine cells: 49.2;Granulosa cells: 122.4;Intestinal goblet cells: 34.7;Proximal enterocytes: 18.8;Undifferentiated cells: 23.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 45.8;endometrial cancer: 30.9" "Region enriched" "Detected in single" 6 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 16.4;OE19: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 23000000 "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.63e-2)" "prognostic favorable (3.67e-6)" "unprognostic (4.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.28e-1)" "unprognostic (1.06e-1)" "unprognostic (5.86e-2)" "unprognostic (2.74e-1)" "unprognostic (6.31e-2)" "unprognostic (3.33e-3)" "unprognostic (1.81e-3)" "unprognostic (2.05e-1)" "unprognostic (5.31e-1)" "unprognostic (1.51e-2)" "unprognostic (2.91e-2)" 0.1 0.0 0.0 2.0 0.0 0.0 0.1 0.1 2.4 4.9 0.0 22.3 12.2 14.0 0.0 0.3 0.9 0.7 0.0 0.0 0.0 2.4 3.5 1.3 0.0 0.3 0.1 0.4 0.0 0.0 0.5 0.1 0.4 2.4 12.4 0.0 0.0 0.7 0.0 0.0 12.9 0.7 0.2 0.0 15.0 0.1 0.1 0.0 1.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.4 0.0 0.0 0.3 0.1 0.4 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.8 0.0 1.8 0.0 0.0 0.4 31.5 0.0 0.1 0.0 6.0 0.5 0.1 49.2 0.0 0.0 3.3 0.0 0.1 12.2 8.9 0.0 122.4 0.0 0.6 0.0 0.0 0.0 34.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 14.0 0.0 0.0 1.8 18.8 3.2 0.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 23.6 0.3 NHEJ1 "Cernunnos, FLJ12610, XLF" ENSG00000187736 "Non-homologous end joining factor 1" Q9H9Q4 2 219069357-219160865 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.8;Microglial cells: 11.2;Oligodendrocytes: 8.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012334, HPA043869" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center" "CAB012334: , HPA043869: AB_2678707" "unprognostic (5.66e-2)" "unprognostic (3.01e-2)" "unprognostic (3.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-2)" "unprognostic (5.92e-2)" "unprognostic (5.16e-2)" "unprognostic (6.04e-2)" "unprognostic (3.51e-2)" "unprognostic (6.87e-2)" "unprognostic (1.58e-3)" "unprognostic (4.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (8.29e-2)" 10.2 8.4 2.4 4.4 2.5 4.5 8.5 3.8 3.8 9.4 2.2 14.0 6.9 8.7 4.3 7.2 7.4 4.8 6.2 2.4 2.9 12.8 8.1 6.9 6.1 3.3 2.5 9.1 8.4 3.4 2.8 4.6 3.2 6.7 8.4 3.4 5.7 4.3 17.1 8.4 12.2 8.1 2.7 6.9 9.0 18.7 2.7 6.1 4.6 7.6 5.8 10.4 8.7 3.5 5.5 8.2 13.9 12.6 15.6 17.9 8.0 10.9 9.6 13.2 15.4 25.4 5.9 12.2 8.4 11.4 13.4 7.2 20.5 10.9 11.8 13.8 9.0 18.1 10.0 17.5 12.5 8.5 13.9 15.5 21.2 10.5 12.5 8.9 11.1 7.8 22.3 11.8 10.7 4.6 11.5 10.3 15.9 5.1 8.0 14.6 10.2 9.8 10.5 8.2 10.2 11.4 5.0 7.1 15.8 15.6 6.4 8.0 9.9 10.0 9.3 4.4 9.1 6.3 8.0 13.2 6.1 16.2 10.3 6.3 11.9 6.6 7.0 17.7 12.2 12.0 11.4 9.3 8.7 9.0 14.1 10.4 3.3 11.6 15.6 4.8 12.8 9.1 2.4 2.5 3.8 3.8 2.4 2.9 3.3 2.5 3.2 2.7 2.7 3.5 0.3 0.0 0.0 5.9 3.5 0.4 0.0 0.2 5.7 0.0 0.2 0.1 0.1 0.0 0.7 0.0 0.0 0.2 1.7 7.8 0.0 1.6 0.7 0.1 0.3 1.0 2.4 3.8 4.7 1.9 0.3 0.6 5.6 0.2 0.0 0.0 0.0 0.3 0.3 0.0 5.1 3.4 0.0 0.0 0.0 0.2 0.3 2.1 0.0 11.2 3.1 0.0 0.0 5.0 8.1 1.0 2.9 0.0 6.1 0.2 3.4 0.4 0.0 0.0 0.0 0.1 1.3 0.2 0.5 5.9 0.0 0.3 2.6 0.2 3.1 0.0 SLC23A3 "FLJ31168, SVCT3, Yspl1" ENSG00000213901 "Solute carrier family 23 member 3" Q6PIS1 2 219161465-219170095 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 8 "intestine: 18.4;kidney: 45.6" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 55.9;Proximal tubular cells: 14.4" "Cancer enriched" "Detected in some" 9 "renal cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 4.9;U-266/70: 3.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected" "Not detected" HPA019059 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA019059: AB_1857017" "unprognostic (2.49e-2)" "unprognostic (6.65e-2)" "unprognostic (2.05e-4)" "unprognostic (6.97e-2)" "unprognostic (8.41e-2)" "unprognostic (1.22e-2)" "unprognostic (9.07e-2)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (4.35e-2)" "unprognostic (3.10e-1)" "unprognostic (6.12e-4)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (2.41e-2)" "unprognostic (3.34e-1)" "unprognostic (6.52e-5)" 1.1 0.4 1.0 0.9 1.0 0.1 0.9 1.2 0.9 2.8 1.0 3.8 7.6 1.6 0.5 2.2 1.5 0.5 1.0 1.0 1.0 45.6 4.0 1.3 0.7 1.1 1.0 1.8 1.1 0.8 0.5 1.0 1.0 2.4 1.5 0.2 1.0 0.6 0.2 1.9 18.4 0.7 1.0 1.5 1.2 0.1 1.1 0.3 2.4 0.1 0.8 1.1 2.3 1.0 0.5 0.2 0.1 0.6 2.0 1.1 0.4 1.2 0.3 0.2 0.7 1.1 0.7 0.2 0.4 0.8 0.0 1.7 0.4 0.1 0.3 1.1 0.9 1.1 1.2 0.1 0.4 0.1 0.4 0.4 4.9 0.4 1.5 1.9 0.6 0.6 0.1 0.4 0.3 0.2 0.0 0.5 0.0 0.4 0.1 0.3 0.3 0.4 1.6 1.9 0.2 0.5 0.1 0.0 1.3 0.5 0.5 0.5 1.4 1.1 0.7 1.0 0.4 3.1 0.1 1.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 1.2 0.9 1.0 1.0 1.1 1.0 1.0 1.0 1.1 1.0 0.6 0.0 0.5 0.0 1.7 1.5 1.4 0.5 0.6 1.1 0.9 1.1 0.3 1.5 0.3 1.8 0.0 0.3 0.5 3.8 1.9 0.2 0.0 0.2 0.8 1.0 1.8 0.4 0.3 0.0 0.1 0.8 0.0 0.9 0.0 0.5 1.1 1.2 0.2 0.0 0.3 4.0 0.0 0.9 0.8 0.0 1.5 1.0 1.8 1.0 1.1 1.2 0.0 0.0 0.0 0.4 6.0 1.2 0.2 1.5 55.9 14.4 0.1 0.2 0.0 0.8 1.0 0.0 0.2 0.7 1.6 0.4 0.8 0.6 3.9 0.9 CNPPD1 "C2orf24, CGI-57" ENSG00000115649 "Cyclin Pas1/PHO80 domain containing 1" Q9BV87 2 219171897-219178106 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049303 Uncertain NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "HPA049303: AB_2680703" "unprognostic (9.24e-2)" "unprognostic (4.12e-2)" "unprognostic (1.09e-1)" "unprognostic (9.43e-2)" "unprognostic (3.68e-2)" "unprognostic (5.74e-3)" "prognostic unfavorable (2.04e-4)" "unprognostic (1.77e-1)" "unprognostic (4.15e-3)" "unprognostic (5.54e-3)" "unprognostic (8.53e-2)" "unprognostic (2.35e-1)" "prognostic favorable (1.62e-10)" "unprognostic (1.48e-2)" "unprognostic (1.51e-1)" "unprognostic (2.62e-2)" "unprognostic (2.54e-2)" 62.0 90.8 43.0 41.4 50.4 78.6 51.6 51.5 46.9 45.7 36.8 70.3 58.9 46.2 37.2 81.2 39.2 27.9 67.2 41.9 47.0 91.0 49.3 41.3 54.3 52.4 49.3 48.2 53.3 89.3 24.7 30.1 51.4 46.8 43.9 16.5 52.2 41.4 97.2 70.8 69.9 34.4 49.4 71.7 54.0 42.1 47.0 43.6 60.2 57.1 51.7 55.3 47.5 56.7 43.3 32.0 31.5 58.3 63.5 31.7 44.8 54.7 32.0 44.5 35.4 69.3 52.3 24.5 31.5 53.6 35.5 59.1 42.0 44.2 25.9 63.3 24.6 100.1 34.2 69.5 77.7 59.4 66.5 33.8 55.8 44.0 39.2 39.9 37.7 65.4 81.3 89.5 26.1 78.7 65.3 45.2 20.2 49.9 40.4 96.0 23.3 83.6 69.3 59.7 40.8 48.8 31.4 77.8 59.2 34.1 62.3 67.2 35.9 36.2 33.8 71.6 52.7 70.4 29.9 52.8 48.9 70.2 23.7 82.6 63.4 65.5 53.2 95.2 46.3 79.4 51.6 54.2 97.6 87.7 35.5 39.9 76.4 56.9 122.3 53.4 73.2 79.4 43.0 50.4 51.5 46.9 41.9 47.0 52.4 49.3 51.4 49.4 47.0 56.7 23.4 19.2 17.7 6.2 61.4 13.5 14.0 32.9 19.4 11.8 24.0 23.4 24.8 34.3 23.7 42.3 4.2 31.9 46.3 90.8 56.7 36.7 1.9 12.4 16.4 22.1 28.9 46.3 4.2 33.3 21.3 22.8 26.0 27.4 13.3 12.7 26.4 23.7 37.7 11.8 5.6 48.9 38.7 45.2 29.0 4.7 22.4 36.1 21.4 10.3 85.8 28.0 55.6 5.5 13.4 39.9 45.6 21.1 34.3 23.1 73.9 64.2 11.5 12.1 19.7 11.5 21.8 26.5 33.5 28.5 15.9 55.0 38.6 19.1 42.9 16.0 RETREG2 "C2orf17, FAM134A, MAG-2, MGC3035" ENSG00000144567 "Reticulophagy regulator family member 2" Q8NC44 2 219176225-219185475 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 42.1;Collecting duct cells: 46.0;Ductal cells: 43.8;Exocrine glandular cells: 48.3;Pancreatic endocrine cells: 40.4;Proximal tubular cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011170, HPA011844, HPA075910" Approved Approved Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA011170: AB_1845713, HPA011844: AB_2668544, HPA075910: " "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (7.95e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (1.49e-4)" "unprognostic (8.74e-2)" "unprognostic (9.61e-2)" "unprognostic (1.34e-2)" "unprognostic (4.37e-2)" "unprognostic (2.36e-1)" "unprognostic (4.29e-3)" "unprognostic (4.45e-2)" "unprognostic (4.47e-2)" "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" 34.4 47.6 73.6 26.5 74.1 47.4 34.1 73.2 90.1 42.7 66.1 41.3 31.7 35.1 45.9 38.5 38.4 32.1 24.6 74.9 76.6 51.8 57.2 29.7 34.3 77.4 77.3 51.9 52.4 76.6 43.7 28.3 77.2 36.9 38.5 50.6 39.8 29.7 24.9 45.0 36.7 33.9 76.5 38.2 42.9 104.0 78.8 34.3 44.6 27.7 34.6 37.7 35.9 78.0 34.6 36.2 30.5 46.5 113.2 47.7 32.5 41.4 71.3 49.4 42.7 36.3 58.1 28.1 40.4 78.5 101.4 43.3 37.1 37.1 54.1 39.5 31.0 37.5 51.2 61.1 64.7 41.1 49.6 52.0 95.5 55.5 53.3 84.7 45.2 29.9 26.3 62.8 69.3 50.9 24.8 44.4 22.6 44.0 41.5 31.4 33.8 22.7 41.1 40.3 43.6 44.9 26.7 50.8 98.4 47.4 42.4 44.9 36.0 55.0 29.4 78.6 31.5 63.4 39.3 31.5 57.5 40.3 31.0 12.5 6.3 6.3 9.3 8.3 8.3 8.3 7.4 9.5 4.3 5.7 6.6 8.8 23.5 5.2 8.1 6.6 9.6 3.6 73.6 74.1 73.2 90.1 74.9 76.6 77.4 77.3 77.2 76.5 78.8 78.0 22.4 16.0 13.7 0.0 7.9 0.0 0.0 0.0 0.0 0.0 42.1 32.0 0.0 0.0 6.2 46.0 0.0 31.1 21.1 0.0 21.5 43.8 0.0 21.4 19.3 8.6 0.0 0.0 0.0 48.3 37.2 11.9 0.0 30.5 5.1 29.2 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 11.4 0.0 0.0 0.0 0.0 40.4 0.0 0.0 5.7 0.0 0.0 42.3 2.2 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 30.1 8.2 24.2 0.0 0.0 ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 144.0;Proximal enterocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "HPA035159: AB_2674499, HPA035160: AB_10670697" "unprognostic (3.71e-1)" "unprognostic (5.49e-3)" "unprognostic (2.77e-3)" "unprognostic (2.59e-1)" "unprognostic (2.97e-1)" "unprognostic (6.85e-3)" "unprognostic (1.40e-2)" "unprognostic (2.27e-1)" "unprognostic (7.36e-2)" "unprognostic (1.20e-1)" "prognostic favorable (9.38e-4)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-3)" "unprognostic (1.32e-1)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" 28.5 26.6 33.2 20.7 34.3 38.2 28.3 34.4 43.7 38.2 27.4 41.6 41.5 29.7 18.1 48.8 28.5 20.0 28.1 33.3 34.0 44.1 64.5 32.3 28.4 37.2 33.3 29.0 40.7 26.8 36.2 17.4 34.3 31.3 25.0 10.8 27.7 17.6 34.3 42.5 45.4 15.9 33.1 45.9 37.4 15.6 34.3 37.9 49.8 15.5 23.3 33.0 35.5 37.5 23.0 14.4 17.2 23.7 17.6 18.5 23.5 22.8 26.3 32.1 31.7 34.8 18.9 16.5 23.0 39.2 26.0 15.5 15.4 28.9 25.5 27.8 25.2 41.8 25.6 30.3 36.3 22.9 45.3 15.3 62.2 31.9 75.0 17.7 21.2 40.0 25.0 38.9 31.9 40.0 37.9 47.9 8.9 31.7 17.5 22.4 8.3 31.6 29.6 17.7 33.7 16.3 10.9 17.3 24.8 19.3 15.4 47.3 22.5 32.2 29.5 37.2 33.3 20.2 6.6 34.1 31.5 44.2 25.6 30.8 34.8 48.6 49.1 46.0 42.5 43.6 44.2 48.0 26.7 53.0 39.9 48.9 58.3 53.5 38.3 33.5 51.6 44.3 33.2 34.3 34.4 43.7 33.3 34.0 37.2 33.3 34.3 33.1 34.3 37.5 30.4 22.4 21.2 17.6 43.5 27.1 26.3 34.0 19.9 14.9 37.1 33.7 12.7 44.3 24.5 20.2 14.6 26.9 52.4 144.0 56.7 44.1 4.9 14.6 17.7 26.4 40.2 15.2 17.8 66.0 24.3 19.6 42.3 20.7 32.4 11.6 23.6 39.4 34.9 8.4 16.1 67.5 36.7 32.4 31.3 7.8 32.0 35.6 35.6 5.6 24.4 21.5 44.3 6.0 15.3 60.3 101.1 29.7 39.5 25.1 170.6 79.5 13.8 17.2 26.3 15.9 28.7 6.2 22.9 27.6 36.1 51.3 46.7 27.8 54.4 28.8 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.8;Late spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" 25.6 23.6 27.2 17.3 29.0 44.7 19.2 27.8 36.6 19.5 10.0 25.6 31.4 24.1 14.2 31.4 18.8 21.8 42.1 30.0 24.3 20.0 25.9 23.7 19.4 29.0 26.7 20.4 28.1 31.2 17.6 30.7 26.2 21.6 21.8 24.6 23.9 22.8 116.8 32.1 29.7 28.1 24.3 21.7 22.8 62.2 27.6 15.7 18.4 62.7 21.2 22.7 22.7 28.6 29.4 35.7 26.9 64.0 50.3 55.1 35.9 52.1 56.1 67.3 60.2 52.9 38.8 7.7 43.7 79.8 54.7 58.0 43.2 56.9 49.6 22.6 70.7 55.7 90.1 63.9 54.9 14.1 40.6 56.7 91.4 68.7 63.0 60.9 68.2 18.6 75.6 27.0 46.2 38.3 12.2 33.4 19.5 28.5 26.9 16.9 36.7 30.2 40.0 38.6 42.6 25.7 52.0 46.7 46.5 52.0 17.3 39.3 52.5 67.0 32.3 28.7 47.1 15.5 14.7 11.2 55.7 33.9 37.2 6.5 12.4 6.3 7.2 18.0 7.2 5.6 5.6 9.1 8.5 3.6 5.4 6.1 11.2 9.7 22.6 4.1 7.1 11.6 27.2 29.0 27.8 36.6 30.0 24.3 29.0 26.7 26.2 24.3 27.6 28.6 0.3 0.0 4.5 12.7 8.2 7.8 7.6 10.6 8.6 18.9 0.3 0.3 33.2 17.2 7.1 0.0 14.6 26.8 4.1 44.0 0.0 0.2 83.8 0.6 1.5 10.0 13.8 34.7 15.2 0.5 24.4 9.1 11.7 0.8 10.2 0.3 16.8 37.1 11.5 21.9 14.1 17.6 6.1 13.3 7.0 105.9 14.0 4.8 10.6 5.6 7.0 20.5 9.2 9.5 12.5 0.3 27.6 8.6 6.7 13.4 39.3 0.3 4.7 15.7 13.1 7.1 5.5 54.9 13.8 14.2 11.1 34.8 7.5 0.8 18.5 10.5 ANKZF1 "FLJ10415, Vms1, ZNF744" ENSG00000163516 "Ankyrin repeat and zinc finger peptidyl tRNA hydrolase 1" Q9H8Y5 2 219229783-219236679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035208 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035208: AB_10602229" "unprognostic (5.23e-2)" "unprognostic (2.23e-1)" "unprognostic (1.12e-3)" "unprognostic (8.27e-2)" "unprognostic (3.38e-1)" "unprognostic (7.95e-3)" "prognostic unfavorable (3.09e-5)" "unprognostic (3.87e-2)" "unprognostic (9.68e-3)" "unprognostic (7.82e-3)" "unprognostic (1.24e-2)" "unprognostic (3.26e-3)" "prognostic unfavorable (2.01e-6)" "unprognostic (1.49e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.88e-3)" 9.1 9.2 7.8 8.8 8.6 7.8 10.8 9.9 9.8 13.8 9.6 13.1 9.6 10.1 3.2 15.2 13.5 6.1 14.1 7.9 8.0 13.9 14.4 10.7 13.7 10.1 8.5 16.0 15.6 6.4 12.5 5.9 9.3 15.1 5.2 8.2 15.3 5.6 16.9 17.3 15.2 4.6 7.9 18.1 14.2 7.9 8.7 11.9 11.9 8.1 8.3 12.4 15.0 10.5 31.6 6.1 8.1 11.8 10.6 8.8 32.5 10.1 10.0 13.6 17.2 14.9 13.2 6.6 18.0 4.3 15.3 22.7 10.5 17.5 10.0 13.9 11.0 14.6 19.1 13.9 10.6 9.6 13.7 8.9 33.1 10.1 15.9 22.6 9.4 17.0 24.8 14.9 6.9 13.6 14.1 24.1 13.5 13.7 10.9 14.3 9.9 21.4 7.6 7.9 10.3 10.5 11.9 23.9 19.8 19.5 6.4 23.7 10.3 11.4 8.7 10.1 13.3 31.6 19.9 12.9 19.4 13.8 5.1 9.9 9.1 11.0 16.1 9.0 17.4 13.0 16.3 16.2 9.4 13.3 19.0 18.0 12.3 24.4 14.0 9.8 17.1 13.6 7.8 8.6 9.9 9.8 7.9 8.0 10.1 8.5 9.3 7.9 8.7 10.5 10.2 16.0 17.2 24.2 28.0 9.3 14.5 28.9 9.6 39.8 14.4 13.6 9.2 11.5 24.8 12.9 31.3 10.5 32.7 17.3 13.7 20.5 4.4 28.2 9.7 11.8 9.6 19.6 19.0 12.6 27.2 8.9 17.9 13.0 21.6 21.4 8.6 13.1 7.7 32.0 21.0 19.1 20.3 8.2 5.3 4.0 23.9 10.9 10.6 6.5 15.6 18.0 43.3 13.6 25.3 14.2 16.0 16.6 17.7 13.6 25.2 16.5 65.1 55.4 6.6 13.2 12.8 10.1 17.0 8.3 9.9 11.6 30.0 21.3 17.6 11.1 GLB1L MGC10771 ENSG00000163521 "Galactosidase beta 1 like" Q6UWU2 2 219236598-219245478 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 52.3" "Cell type enhanced" "Detected in many" "Early spermatids: 41.5;Spermatocytes: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043058 Enhanced "Secreted - unknown location" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA043058: AB_10806375" "unprognostic (4.30e-2)" "unprognostic (6.93e-2)" "unprognostic (2.68e-2)" "unprognostic (2.08e-3)" "unprognostic (4.35e-2)" "unprognostic (1.51e-1)" "unprognostic (1.67e-3)" "unprognostic (3.32e-2)" "unprognostic (4.77e-1)" "unprognostic (2.39e-1)" "unprognostic (8.48e-3)" "unprognostic (3.27e-1)" "unprognostic (3.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.23e-3)" "unprognostic (1.33e-1)" "unprognostic (8.50e-2)" 4.6 4.8 3.1 4.0 3.4 4.5 5.3 3.3 3.0 5.3 14.7 3.1 3.1 5.9 11.4 2.5 23.1 9.0 2.2 3.0 3.7 13.6 3.1 5.3 3.0 5.5 7.0 7.1 3.1 14.4 6.8 8.5 4.5 5.6 3.7 8.0 4.5 4.8 0.9 4.6 4.1 5.8 4.4 4.9 2.8 52.3 3.7 3.4 8.4 1.0 3.4 5.9 2.1 5.6 2.8 4.8 7.4 5.9 8.0 9.8 3.7 4.6 9.7 5.7 5.3 1.9 7.7 0.9 4.1 4.1 4.3 1.5 1.9 4.6 4.5 2.6 3.6 2.9 6.9 4.5 19.7 1.1 4.4 11.4 2.9 5.4 3.3 13.5 5.3 4.3 1.8 5.3 5.4 4.0 2.5 2.7 1.3 1.0 1.3 2.5 4.1 4.0 11.5 1.6 4.7 4.2 3.9 5.3 4.3 4.9 8.4 2.6 4.1 4.7 5.8 2.8 2.6 5.0 1.7 1.5 8.8 1.2 12.3 1.9 5.1 0.3 0.7 6.4 0.4 0.4 0.5 0.7 2.1 1.0 1.1 0.7 2.1 1.0 5.4 0.9 0.2 1.7 3.1 3.4 3.3 3.0 3.0 3.7 5.5 7.0 4.5 4.4 3.7 5.6 3.2 3.2 5.1 3.3 1.3 1.8 2.6 3.6 0.6 4.7 4.9 5.6 1.9 1.5 6.3 3.7 12.5 3.4 1.9 1.1 3.9 3.8 41.5 15.7 3.9 4.2 4.9 1.3 0.9 1.8 2.2 8.4 1.1 2.2 0.0 2.7 8.6 1.3 14.5 3.3 1.1 3.2 2.0 5.6 2.4 25.6 10.8 4.4 8.8 1.9 2.7 5.0 3.1 1.0 0.5 2.1 3.3 6.4 1.8 2.7 6.5 16.5 23.9 10.2 6.6 3.8 2.2 117.4 9.7 1.8 1.7 1.4 2.0 7.0 2.4 1.7 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 15.2 24.9 17.6 11.8 17.5 15.0 16.2 16.3 20.5 14.0 19.5 20.0 17.3 13.8 20.8 22.8 18.1 13.0 19.0 16.5 16.8 26.5 43.2 14.3 17.6 17.9 17.5 14.8 30.9 22.7 19.8 9.2 16.9 20.3 13.5 7.9 20.0 10.9 14.4 17.3 17.8 9.9 17.4 21.2 24.2 27.7 18.6 20.5 19.3 8.2 14.5 17.8 14.8 16.5 14.1 18.8 15.7 13.2 40.0 40.0 17.9 17.8 23.6 14.3 14.7 21.2 31.0 8.3 24.4 32.0 23.4 14.5 18.5 30.0 7.8 20.0 19.8 17.7 15.4 19.1 34.9 17.6 20.1 40.1 48.1 20.8 57.4 29.8 17.9 18.7 23.1 21.5 26.8 27.1 19.4 38.0 14.5 25.7 10.3 18.1 17.5 24.9 32.2 16.1 12.3 14.6 5.8 25.5 39.0 11.2 27.4 36.4 13.7 20.6 14.0 16.4 17.4 25.9 12.1 19.5 22.9 18.4 18.3 1.6 7.0 5.3 4.9 3.8 5.5 7.2 6.0 9.2 6.8 6.0 6.1 7.9 4.1 14.5 3.1 5.8 7.3 8.7 17.6 17.5 16.3 20.5 16.5 16.8 17.9 17.5 16.9 17.4 18.6 16.5 11.8 6.4 5.6 3.6 22.4 9.8 18.1 32.6 24.5 7.9 31.8 31.8 9.5 24.3 19.7 7.3 16.7 24.0 23.6 27.6 68.4 40.3 87.2 21.4 13.3 14.0 25.8 36.0 2.2 58.5 25.0 15.8 17.3 12.9 8.2 17.9 12.5 43.7 28.4 13.5 2.7 38.7 16.2 27.1 17.6 70.3 15.2 17.8 21.4 0.0 38.4 22.1 44.3 4.0 6.8 33.3 44.3 13.5 27.6 18.6 58.9 80.2 19.6 19.1 0.0 11.9 19.2 43.1 9.6 28.2 11.2 12.9 22.1 33.6 34.2 20.8 TUBA4A "FLJ30169, H2-ALPHA, TUBA1" ENSG00000127824 "Tubulin alpha 4a" P68366 2 219249710-219278170 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 360.2;tongue: 210.3" "Cell type enhanced" "Detected in many" "Early spermatids: 423.0;Late spermatids: 823.0;Pancreatic endocrine cells: 613.5;Smooth muscle cells: 408.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HaCaT: 265.9;HBEC3-KT: 439.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004621, CAB005887, HPA039247, HPA043684, HPA063394" Approved Enhanced Microtubules NA NA 130000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" Microtubules "CAB004621: AB_628411, CAB005887: AB_2288001, HPA039247: AB_2676410, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (8.08e-2)" "unprognostic (2.31e-1)" "unprognostic (4.03e-2)" "unprognostic (2.56e-2)" "unprognostic (5.18e-3)" "unprognostic (3.99e-2)" "prognostic unfavorable (4.54e-6)" "unprognostic (1.52e-3)" "unprognostic (4.47e-1)" "unprognostic (8.85e-2)" "unprognostic (1.49e-2)" "unprognostic (5.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.70e-1)" "unprognostic (2.36e-1)" "unprognostic (7.38e-3)" "unprognostic (9.32e-2)" 14.3 41.4 33.6 34.1 47.5 107.1 16.4 22.3 133.1 27.7 8.1 32.9 18.6 9.8 10.1 84.8 12.6 13.5 97.7 42.6 32.3 31.9 29.5 26.7 56.7 46.3 27.3 12.9 18.2 34.6 23.1 5.0 31.4 19.7 27.8 39.2 46.9 22.4 360.2 161.4 35.5 12.8 3.9 56.8 30.6 32.4 14.9 16.9 12.3 210.3 63.4 22.6 57.3 54.0 106.0 90.0 0.0 0.3 9.1 6.9 0.3 16.2 49.7 2.8 1.9 20.4 106.7 144.2 172.2 11.7 172.7 265.9 49.3 439.9 3.9 81.7 0.7 184.2 154.5 15.4 7.3 60.9 60.8 6.7 158.0 23.7 49.2 27.4 17.3 2.4 20.5 91.3 100.6 4.3 0.3 107.9 32.3 83.2 107.4 6.5 139.0 84.5 129.7 7.5 85.8 1.5 213.2 18.7 0.7 1.8 8.0 50.9 12.3 49.8 27.4 58.4 56.7 38.0 48.8 171.4 183.3 116.4 2.5 141.7 63.3 170.2 107.1 45.7 110.1 124.9 150.3 142.8 20.9 95.5 140.2 138.4 331.2 82.0 71.9 3.8 143.8 270.9 33.6 47.5 22.3 133.1 42.6 32.3 46.3 27.3 31.4 3.9 14.9 54.0 55.3 44.8 47.1 16.3 160.6 181.8 201.2 235.3 68.9 123.3 42.3 51.6 60.9 28.6 62.0 49.7 77.2 0.7 311.6 87.3 140.8 199.3 423.0 9.8 3.3 36.5 107.9 56.2 34.8 205.6 0.5 11.5 40.8 26.1 15.8 0.1 36.0 33.0 6.0 67.3 22.5 141.9 48.8 15.3 54.9 823.0 16.8 159.5 78.2 9.4 27.8 38.6 50.4 10.6 10.6 613.5 51.2 7.5 202.3 46.7 87.5 137.5 11.1 72.9 0.0 21.1 408.5 5.7 5.0 130.6 244.5 2.5 290.1 1.4 58.9 113.0 TUBA4B "FLJ13940, TUBA4" ENSG00000243910 "Tubulin alpha 4b" Q9H853 2 219253243-219272197 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "fallopian tube: 40.0" "Group enriched" "Detected in some" 4 "Endometrial ciliated cells: 148.9;Respiratory ciliated cells: 83.1" "Cancer enriched" "Detected in some" 6 "endometrial cancer: 8.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (3.20e-5)" "unprognostic (1.47e-4)" "unprognostic (1.85e-1)" "unprognostic (3.70e-3)" "unprognostic (9.63e-2)" "unprognostic (8.97e-2)" "unprognostic (2.18e-3)" "unprognostic (7.32e-2)" "unprognostic (9.50e-2)" "unprognostic (6.56e-2)" "unprognostic (2.50e-1)" "unprognostic (2.12e-1)" "unprognostic (2.41e-3)" "unprognostic (3.78e-2)" "unprognostic (9.57e-2)" "unprognostic (3.91e-2)" "unprognostic (4.08e-1)" 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.2 0.1 1.5 4.7 0.0 0.1 0.5 0.7 0.0 40.0 0.0 0.0 0.4 0.8 1.5 0.2 3.5 0.1 1.9 3.6 0.1 0.0 0.0 0.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.4 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.2 0.3 0.3 0.6 0.1 0.1 0.0 0.3 1.4 0.8 0.6 0.2 0.1 0.4 0.8 1.9 3.6 1.8 1.8 0.7 1.4 0.0 0.0 3.2 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.3 1.8 0.0 0.0 0.0 0.0 1.9 0.0 1.8 148.9 0.9 0.1 1.8 0.0 0.3 0.2 0.0 0.2 0.0 2.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 27.9 83.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 DNAJB2 "CMT2T, HSJ1, HSPF3" ENSG00000135924 "DnaJ heat shock protein family (Hsp40) member B2" P25686 2 219279342-219286898 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 366.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036268 Approved Enhanced "Nuclear membrane" NA NA 9900 "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear membrane" "HPA036268: AB_10670793" "unprognostic (2.02e-2)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (2.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.45e-3)" "unprognostic (5.11e-2)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.16e-3)" "unprognostic (7.03e-2)" "unprognostic (4.09e-2)" "unprognostic (4.64e-2)" "unprognostic (1.96e-2)" "unprognostic (5.98e-2)" "unprognostic (5.62e-3)" 41.9 106.9 264.5 17.7 290.6 26.6 45.7 276.0 323.5 63.8 232.0 48.9 23.2 46.2 45.2 54.1 48.2 26.6 85.4 266.6 270.7 81.0 72.1 45.8 26.0 281.8 281.8 65.0 84.8 54.3 112.1 27.1 279.7 73.9 15.8 63.9 62.3 35.5 135.6 108.1 36.0 15.8 269.7 46.7 54.8 86.0 280.5 28.4 71.0 56.5 20.5 52.8 59.0 366.0 34.9 14.2 21.9 20.7 45.6 22.1 29.3 32.8 27.2 29.0 24.2 66.2 21.3 21.4 39.7 31.6 66.3 49.1 27.9 36.3 16.3 45.3 12.2 41.7 28.0 32.0 30.8 7.1 36.5 21.3 103.3 31.8 38.4 51.3 12.9 23.5 7.4 23.7 21.4 18.0 13.0 8.4 12.9 30.2 26.4 13.4 17.9 13.5 31.7 24.5 20.6 26.0 38.0 38.4 64.9 57.5 28.6 14.9 17.5 41.6 82.3 12.0 28.6 26.2 8.4 35.0 42.8 6.5 31.1 0.0 0.4 2.1 0.7 0.4 0.6 0.5 0.7 0.6 0.2 1.7 1.0 0.9 0.4 1.3 1.2 0.6 1.0 0.4 264.5 290.6 276.0 323.5 266.6 270.7 281.8 281.8 279.7 269.7 280.5 366.0 24.6 19.2 31.4 35.6 30.9 28.6 40.9 17.1 9.1 97.9 61.9 33.9 77.4 25.8 18.0 38.6 56.3 36.1 24.0 41.5 78.2 60.0 43.8 43.5 16.2 22.3 53.7 69.9 17.9 33.5 34.7 27.5 22.4 27.9 24.8 22.1 20.7 20.5 28.2 80.8 26.5 47.5 10.2 19.7 28.2 70.9 36.4 28.0 32.0 11.2 21.6 84.8 15.5 16.6 144.2 68.9 23.6 39.1 28.5 39.8 31.7 56.5 39.0 87.3 19.7 27.3 28.3 56.5 20.6 18.9 50.4 69.0 30.2 23.1 25.5 25.8 PTPRN "IA-2, ICA512" ENSG00000054356 "Protein tyrosine phosphatase receptor type N" Q16849 2 219289623-219309648 "Disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Receptor "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 234.3;pituitary gland: 182.3" "Group enriched" "Detected in some" 9 "Bipolar cells: 59.0;Cone photoreceptor cells: 60.5;Enteroendocrine cells: 47.1;Excitatory neurons: 44.6;Horizontal cells: 97.6;Inhibitory neurons: 48.1;Rod photoreceptor cells: 38.4" "Group enriched" "Detected in some" 12 "glioma: 5.3;pancreatic cancer: 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "U-2 OS: 66.4;U-87 MG: 249.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007152, HPA007179" Enhanced Approved "Endoplasmic reticulum" NA NA 38000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Endoplasmic reticulum" "HPA007152: AB_2667759, HPA007179: AB_1079714" "unprognostic (1.43e-1)" "unprognostic (1.33e-4)" "unprognostic (2.91e-3)" "unprognostic (5.83e-3)" "prognostic unfavorable (1.45e-7)" "unprognostic (3.64e-2)" "unprognostic (1.24e-4)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (6.20e-4)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-10)" "unprognostic (1.43e-2)" "unprognostic (2.49e-1)" "unprognostic (1.10e-2)" "unprognostic (8.61e-2)" 0.7 25.2 91.6 4.8 98.3 0.6 0.2 12.2 139.0 0.2 0.0 5.3 1.6 0.3 0.0 0.3 0.1 0.3 0.3 116.6 234.3 0.3 0.2 0.2 0.1 62.4 85.5 0.2 36.3 0.0 182.3 0.2 138.1 0.4 0.8 21.4 0.1 0.0 0.1 0.9 2.0 1.6 22.2 0.1 6.0 0.7 98.9 0.0 0.4 0.0 0.0 0.9 0.9 70.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 2.5 0.0 0.8 0.0 0.1 0.0 0.0 1.2 4.6 6.8 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.8 1.9 0.0 0.6 8.4 0.0 20.8 0.0 0.2 0.0 0.0 0.4 0.5 1.5 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 10.8 0.0 0.0 0.0 9.0 0.0 0.1 0.0 0.1 66.4 0.0 0.2 0.1 0.3 1.1 249.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 91.6 98.3 12.2 139.0 116.6 234.3 62.4 85.5 138.1 22.2 98.9 70.1 0.0 0.0 0.0 5.5 0.1 0.1 0.1 0.1 0.0 59.0 0.1 0.1 2.0 0.0 0.0 0.0 60.5 0.0 0.1 0.1 1.9 0.1 0.3 0.1 0.2 0.7 47.1 2.7 44.6 0.0 0.3 1.9 2.6 0.0 0.0 0.0 0.0 0.3 0.1 97.6 48.1 0.7 2.0 0.0 0.4 0.8 0.3 1.8 1.8 4.7 0.0 6.0 0.0 1.5 4.0 2.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 38.4 0.0 0.1 1.9 4.2 2.7 0.0 0.1 0.0 0.1 0.0 0.1 0.2 RESP18 ENSG00000182698 "Regulated endocrine specific protein 18" Q5W5W9 2 219327407-219333177 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "brain: 14.8" "Group enriched" "Detected in some" 6 "Early spermatids: 9.4;Late spermatids: 32.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.57e-2)" "unprognostic (2.12e-1)" 0.0 0.0 2.9 0.0 14.8 0.0 0.0 1.5 7.4 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.4 0.0 0.0 0.0 0.0 3.8 5.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.4 5.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 14.8 1.5 7.4 5.0 5.4 3.8 5.2 4.1 1.9 5.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DNPEP "ASPEP, DAP" ENSG00000123992 "Aspartyl aminopeptidase" Q9ULA0 2 219372043-219400022 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 364.4;Late spermatids: 462.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036398, HPA044860" Enhanced Supported Cytosol NA NA 2700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA036398: AB_10970915, HPA044860: AB_10961275" "unprognostic (3.71e-1)" "unprognostic (6.45e-2)" "unprognostic (1.26e-1)" "unprognostic (1.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.75e-1)" "unprognostic (2.54e-3)" "unprognostic (3.34e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" "unprognostic (1.61e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-1)" "unprognostic (5.63e-3)" "unprognostic (3.49e-1)" "unprognostic (2.50e-1)" "unprognostic (1.85e-3)" 25.8 18.9 15.4 25.0 15.8 18.0 23.6 14.8 18.6 24.9 14.7 34.5 56.5 22.4 21.5 25.1 25.1 22.6 39.9 16.2 16.9 22.1 32.0 27.6 23.4 15.8 15.0 30.2 27.2 25.8 13.0 37.1 15.2 22.6 30.8 9.5 26.2 24.4 64.5 31.7 56.2 19.9 16.0 24.7 25.4 58.5 17.4 17.5 15.2 46.4 16.2 29.6 21.6 14.7 47.5 25.8 15.4 45.7 39.7 32.2 122.0 23.0 46.5 59.3 62.5 72.6 61.2 27.2 48.7 49.5 76.0 45.0 18.6 53.6 21.3 56.4 12.5 46.6 25.0 79.8 107.2 38.9 32.2 54.4 55.4 61.8 50.2 37.9 41.2 38.6 53.8 45.3 31.0 103.7 60.8 44.5 25.5 67.7 15.1 77.2 35.7 36.5 33.0 74.0 19.1 26.0 27.1 86.5 34.5 26.9 25.8 43.3 23.5 55.4 46.1 31.4 33.7 49.6 31.8 21.3 80.0 37.7 24.1 8.7 17.2 7.3 16.1 19.7 18.8 13.2 13.2 18.3 20.8 16.2 14.0 18.7 1.6 21.2 17.0 7.2 16.6 14.8 15.4 15.8 14.8 18.6 16.2 16.9 15.8 15.0 15.2 16.0 17.4 14.7 43.1 12.8 18.2 8.8 35.6 38.6 74.1 55.1 52.9 19.3 41.2 36.7 33.6 55.8 27.2 25.8 33.3 90.4 26.7 70.4 49.0 62.9 364.4 16.5 36.5 41.8 48.0 19.8 3.1 66.3 96.9 43.4 29.0 19.6 24.1 39.1 30.4 47.9 51.0 10.1 5.2 110.3 38.7 31.5 26.8 462.0 52.5 26.2 32.0 4.7 53.0 29.8 45.3 3.0 3.3 52.3 75.6 41.0 38.3 113.1 202.6 79.6 16.3 37.6 26.3 31.9 120.0 20.1 20.1 43.4 44.8 66.4 34.1 36.9 70.9 74.6 DES "CMD1I, CSM1, CSM2" ENSG00000175084 Desmin P17661 2 219418377-219426734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Muscle protein" "Cancer-related genes, Cardiomyopathy, Desmin-related myopathy, Disease variant, Limb-girdle muscular dystrophy, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 13020.7;intestine: 8627.2;skeletal muscle: 16532.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2531.9" "Cancer enhanced" "Detected in all" "prostate cancer: 562.1;stomach cancer: 400.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 70.2;LHCN-M2: 145.3;NB-4: 39.5;RH-30: 333.1" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "midbrain: 29.5" "CAB000034, HPA018803" Enhanced Supported "Intermediate filaments" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "CAB000034: , HPA018803: AB_1847616" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "unprognostic (3.43e-2)" "unprognostic (8.76e-2)" "unprognostic (7.75e-3)" "unprognostic (6.61e-3)" "unprognostic (1.55e-1)" "unprognostic (2.72e-2)" "unprognostic (4.67e-1)" "unprognostic (3.84e-2)" "unprognostic (2.57e-1)" "unprognostic (7.43e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (3.49e-2)" "unprognostic (1.34e-1)" "unprognostic (1.22e-1)" "unprognostic (9.25e-3)" 235.3 57.1 2.1 436.2 4.9 1.1 51.2 2.1 9.6 504.3 5.0 8627.2 291.3 3015.2 86.0 1481.2 1085.0 452.1 13020.7 2.4 2.5 37.6 15.5 173.9 7.2 3.4 2.5 171.8 14.6 0.5 8.4 52.7 2.4 2218.8 245.6 0.0 255.3 2253.1 16532.0 152.4 1343.5 2557.5 2.1 25.2 1965.6 16.1 2.6 3.2 66.2 5753.8 1.2 4761.8 669.4 2.4 0.0 0.0 0.1 0.0 0.0 2.2 5.3 0.2 0.0 0.1 0.1 0.5 0.0 0.0 9.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 17.0 0.1 1.3 70.2 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 145.3 0.0 0.0 39.5 0.5 0.0 0.0 0.0 333.1 2.1 0.0 0.0 0.2 1.2 0.0 0.0 0.0 9.2 0.0 5.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 2.1 4.9 2.1 9.6 2.4 2.5 3.4 2.5 2.4 2.1 2.6 2.4 0.4 0.0 0.0 0.0 0.0 4.1 2.7 0.0 0.0 0.0 0.1 0.0 2531.9 1.5 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 90.6 0.5 6.7 22.7 0.0 0.0 0.1 0.0 5.2 104.6 0.0 0.1 0.0 0.0 1.8 0.0 5.6 0.0 0.0 0.9 0.0 0.0 10.7 71.6 28.9 2.8 12.4 0.0 0.6 0.0 0.0 0.5 0.0 0.5 0.0 50.4 0.0 8.7 0.0 0.1 0.0 0.0 46.0 497.8 210.5 5.0 5.1 0.1 9.8 8.5 2.4 0.0 0.2 2.9 SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Cardiomyocytes: 61.5;Late spermatids: 39.6;Sertoli cells: 46.0;Smooth muscle cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 45.9;U-87 MG: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 16.1 6.8 16.8 7.7 18.7 0.0 15.3 15.5 20.7 75.5 9.7 174.8 5.3 89.5 6.2 15.6 70.0 7.3 48.5 19.8 14.5 4.1 1.3 8.7 0.6 16.1 15.8 21.9 3.4 4.4 34.3 4.5 14.6 58.8 3.8 1.0 10.0 25.5 118.0 7.8 31.9 23.1 15.3 2.4 48.1 5.4 15.3 0.5 5.9 21.7 0.2 87.7 42.1 15.6 6.1 0.5 3.1 4.9 1.6 4.7 1.8 13.1 8.5 8.6 6.4 4.5 1.9 0.0 4.5 9.7 4.3 7.2 2.5 3.1 3.4 0.0 1.7 0.0 6.1 0.3 2.1 0.0 0.5 13.2 4.6 7.8 1.9 45.9 0.0 3.2 3.5 0.0 6.1 1.6 0.1 18.8 6.5 0.0 2.4 2.8 7.0 1.1 8.5 0.0 3.4 15.1 0.6 0.0 0.3 14.3 0.3 0.2 0.0 20.6 21.3 2.4 21.1 0.4 0.0 0.2 23.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 18.7 15.5 20.7 19.8 14.5 16.1 15.8 14.6 15.3 15.3 15.6 2.4 0.0 2.2 45.7 0.4 3.2 6.0 1.3 2.8 5.3 10.3 14.6 61.5 4.3 0.1 1.8 2.1 0.6 1.4 4.1 0.0 1.5 21.8 0.9 3.6 2.2 6.7 2.7 20.5 1.2 0.9 10.0 3.6 1.3 0.0 1.0 5.7 3.1 1.1 5.0 20.9 4.1 0.0 5.6 1.9 39.6 10.5 1.6 3.6 4.7 1.4 8.4 0.0 5.0 1.0 0.2 3.2 18.8 0.9 6.5 8.5 4.3 0.1 0.9 46.0 17.1 32.4 11.6 3.7 0.2 1.4 1.4 1.2 0.4 3.5 5.3 AC053503.6 ENSG00000286143 "Novel protein" 2 219491867-219498244 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "skeletal muscle: 3.4" "Cell type enhanced" "Detected in single" "Early spermatids: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 37: Myocytes - Muscle contraction" 0.2 0.2 0.2 0.3 0.3 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.5 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.4 0.2 0.2 0.4 0.2 0.4 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPEGNB ENSG00000286095 "SPEG neighbor" A0A087WV53 2 219496125-219498287 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "skeletal muscle: 2.5;tongue: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "K-562: 1.0" "Not detected" "Not detected" NA NA "Cluster 1: K-562 - Erythropoiesis" 0.1 0.1 0.2 0.5 0.6 0.0 0.1 0.6 0.4 0.0 0.0 0.1 0.0 0.5 0.0 0.2 0.1 0.2 0.6 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 2.5 0.0 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 2.2 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.5 0.3 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.1 0.2 0.0 0.0 0.8 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.6 0.4 0.1 0.5 0.8 0.4 0.5 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GMPPA ENSG00000144591 "GDP-mannose pyrophosphorylase A" Q96IJ6 2 219498884-219506989 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 79.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035512, HPA035513" Approved Approved Nucleoplasm NA NA 51000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA035512: AB_2674660, HPA035513: AB_10671934" "unprognostic (3.43e-1)" "unprognostic (3.95e-2)" "unprognostic (7.75e-3)" "unprognostic (1.40e-3)" "unprognostic (4.87e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (5.57e-1)" "unprognostic (2.39e-1)" "unprognostic (2.25e-1)" "unprognostic (1.17e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.90e-10)" "prognostic favorable (5.24e-4)" "unprognostic (1.28e-1)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" 22.6 25.8 19.3 23.9 20.1 19.0 21.6 20.1 22.6 32.1 22.4 29.7 28.8 26.4 68.7 25.5 24.6 19.7 27.1 20.1 20.5 25.7 68.5 20.9 20.7 20.5 19.8 20.1 60.3 24.7 48.5 21.2 20.0 37.3 32.3 8.0 40.1 23.4 22.8 17.8 30.0 26.2 19.6 35.2 32.5 9.6 21.3 13.2 28.6 12.6 23.8 25.2 23.1 19.8 43.4 36.0 21.2 37.8 79.5 70.6 56.4 73.8 98.6 85.2 105.2 66.8 40.5 23.4 51.1 107.7 54.3 40.1 39.7 63.9 73.3 45.3 35.0 45.5 35.7 119.3 72.0 24.1 51.7 54.3 50.7 79.9 89.9 43.9 52.8 29.7 82.3 66.3 66.8 55.5 23.8 45.3 21.7 52.8 38.5 18.6 22.9 42.4 48.6 30.1 27.4 24.0 31.0 46.3 52.1 44.4 31.5 38.8 30.9 49.2 33.6 89.4 40.9 45.4 19.4 28.9 100.4 26.7 55.8 76.0 52.6 37.3 30.1 56.0 35.0 32.1 23.4 31.9 43.5 24.1 17.3 15.7 11.8 36.4 59.3 43.9 34.8 35.2 19.3 20.1 20.1 22.6 20.1 20.5 20.5 19.8 20.0 19.6 21.3 19.8 12.5 16.0 14.4 5.5 18.8 5.6 12.8 25.2 6.2 6.1 20.9 13.5 13.2 10.0 20.1 16.5 6.2 37.6 16.6 37.7 35.2 24.3 1.3 8.5 15.8 9.5 10.8 19.1 3.1 30.0 79.8 19.2 38.7 14.4 19.0 13.3 11.0 36.3 33.7 1.7 3.6 61.6 10.2 17.6 10.0 3.4 18.3 16.5 12.4 1.9 15.9 11.1 12.3 1.0 4.9 19.0 37.6 13.5 50.3 15.1 45.9 36.8 11.6 4.7 13.1 7.9 27.1 4.4 6.5 9.9 8.5 47.2 13.5 10.7 29.1 15.1 ASIC4 "ACCN4, BNAC4" ENSG00000072182 "Acid sensing ion channel subunit family member 4" Q96FT7 2 219514170-219538772 "Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 10.7;pituitary gland: 22.0;retina: 6.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 223.4;Cone photoreceptor cells: 173.0" "Cancer enriched" "Detected in single" 38 "glioma: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 21.2;HMC-1: 6.2;K-562: 12.1;SH-SY5Y: 5.2" "Region enhanced" "Detected in many" "basal ganglia: 73.2" "Low region specificity" "Detected in many" HPA036042 Approved "Golgi apparatus" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "HPA036042: AB_10672998" "unprognostic (3.48e-1)" "unprognostic (1.44e-1)" "unprognostic (2.55e-1)" "unprognostic (1.61e-2)" "unprognostic (2.62e-1)" "unprognostic (8.74e-2)" "unprognostic (3.04e-2)" "unprognostic (2.54e-1)" "unprognostic (6.53e-2)" "unprognostic (1.90e-2)" "unprognostic (9.46e-3)" "unprognostic (1.88e-1)" "unprognostic (7.80e-8)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (5.51e-1)" "unprognostic (2.48e-2)" 0.1 1.1 6.1 0.0 4.2 0.0 0.0 4.1 8.4 0.4 2.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 3.9 4.9 0.0 0.0 0.1 0.0 5.5 8.4 0.0 0.0 0.0 22.0 0.0 4.4 0.1 0.0 6.4 0.0 0.1 0.0 0.1 0.0 0.0 5.7 0.0 0.0 1.3 10.7 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 4.2 4.1 8.4 3.9 4.9 5.5 8.4 4.4 5.7 10.7 3.9 0.1 0.0 0.0 0.3 0.0 0.1 1.6 0.1 0.0 223.4 0.9 1.0 1.1 0.0 0.0 0.0 173.0 2.5 0.0 0.7 0.0 0.0 6.1 0.0 0.9 0.4 0.0 0.0 0.3 0.4 1.0 0.9 0.0 0.3 17.8 0.4 0.0 0.0 0.1 0.0 11.6 0.6 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 10.0 0.0 39.2 0.4 0.0 2.5 0.4 0.1 1.1 1.3 0.2 0.0 12.8 0.0 3.1 0.6 0.3 0.6 0.0 0.3 2.9 0.4 0.5 0.9 0.3 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538948-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 163.7;Extravillous trophoblasts: 182.7;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" NA NA 570000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.96e-4)" 29.9 45.7 26.9 12.5 24.9 1.7 22.3 25.8 34.2 59.1 36.7 21.9 26.7 55.9 13.7 27.3 30.2 24.2 134.8 38.4 31.2 41.1 97.8 42.8 6.5 34.0 30.4 127.4 138.9 24.6 128.3 40.6 32.1 58.6 4.7 8.5 56.1 25.6 16.3 26.2 23.2 12.6 27.4 16.6 40.9 97.5 33.2 3.6 52.8 3.9 4.5 34.3 30.0 34.0 67.5 13.0 9.6 81.0 36.0 55.8 109.7 66.4 55.4 18.5 16.8 36.8 57.5 20.7 139.0 64.6 63.3 84.1 6.3 40.3 2.9 32.3 22.5 7.4 18.0 161.9 49.8 6.6 42.1 75.0 69.2 18.8 17.9 66.7 0.1 7.1 47.2 49.6 17.7 105.5 1.0 17.6 39.8 22.8 50.6 0.1 30.4 41.6 22.4 29.7 23.4 36.0 32.1 30.7 94.3 17.9 10.5 22.6 1.6 67.9 37.1 81.9 35.2 58.9 19.9 9.7 62.1 6.7 70.4 1.7 0.0 6.5 1.9 0.1 2.4 1.0 1.5 1.3 0.0 0.1 1.7 0.6 0.0 1.9 0.0 9.5 1.2 0.7 26.9 24.9 25.8 34.2 38.4 31.2 34.0 30.4 32.1 27.4 33.2 34.0 2.1 0.0 15.2 16.0 16.5 14.5 23.2 52.8 17.1 14.6 40.0 29.6 30.5 22.8 31.2 75.4 10.4 163.7 21.7 15.9 9.8 58.1 4.1 14.0 22.2 2.9 43.0 3.2 4.3 80.4 182.7 56.0 25.5 42.4 10.2 27.4 4.2 64.0 18.5 43.7 9.2 57.8 36.7 2.4 9.1 7.1 24.8 2.3 67.6 5.6 1.8 56.8 9.2 5.5 3.7 65.6 32.7 63.2 123.6 42.3 60.7 20.6 14.6 11.5 26.3 19.3 27.1 11.9 6.3 14.2 11.1 310.3 9.7 46.3 14.3 33.0 TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 19.2;Horizontal cells: 21.9;Muller glia cells: 10.9;Proximal enterocytes: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 20.0;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" 3.2 8.2 10.8 1.4 9.7 0.1 3.0 12.1 19.4 4.6 2.3 2.7 8.9 5.2 1.0 2.0 3.6 1.8 4.4 21.0 8.4 4.0 4.3 3.2 0.7 7.7 7.4 14.7 12.0 3.1 18.3 1.1 6.0 4.2 0.6 2.5 3.8 1.8 2.8 1.5 4.4 1.6 7.4 2.2 4.6 5.9 8.5 0.5 4.0 2.0 0.7 3.8 2.0 8.8 0.6 0.1 5.6 9.6 1.1 1.0 4.9 2.8 1.5 2.3 2.0 12.5 1.6 2.6 2.7 1.8 5.8 3.5 2.0 1.4 0.4 8.7 2.4 2.0 2.9 10.4 1.6 0.7 4.7 2.4 0.8 1.1 2.7 2.5 0.0 1.8 7.8 8.1 1.4 1.2 0.1 0.6 7.3 1.0 0.9 0.2 3.4 2.9 1.4 1.4 20.0 17.4 0.7 2.0 5.0 1.0 0.2 4.0 0.1 2.5 1.0 2.3 1.2 7.7 2.4 2.7 2.3 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 10.8 9.7 12.1 19.4 21.0 8.4 7.7 7.4 6.0 7.4 8.5 8.8 0.3 0.0 1.1 2.0 0.8 0.1 1.4 1.4 1.2 9.3 3.5 4.3 1.8 4.3 0.6 0.0 2.1 1.0 0.4 0.4 1.9 3.9 0.8 0.3 2.6 0.4 19.2 0.0 4.9 7.9 0.9 3.9 1.5 0.6 0.0 1.6 0.0 1.6 0.3 21.9 4.8 2.4 2.0 0.3 0.9 1.4 2.8 0.0 1.8 0.0 0.6 10.9 0.0 3.0 1.2 1.5 4.0 4.9 1.1 0.8 12.4 1.8 0.6 7.4 0.0 1.6 2.8 8.4 4.2 0.4 0.1 2.9 0.4 5.5 0.5 0.4 OBSL1 KIAA0657 ENSG00000124006 "Obscurin like cytoskeletal adaptor 1" O75147 2 219550728-219571859 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 337.3" "Group enriched" "Detected in many" 8 "Early spermatids: 1140.1;Late spermatids: 1994.5;Spermatocytes: 572.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.4;plasmacytoid DC: 1.3" "Group enriched" "Detected in many" 11 "dendritic cells: 1.3;granulocytes: 4.4" "Cell line enhanced" "Detected in many" "BEWO: 155.2;SK-BR-3: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036404, HPA036405" Approved Approved Centrosome NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "HPA036404: AB_10670437, HPA036405: AB_2675104" "unprognostic (2.36e-1)" "unprognostic (6.79e-2)" "unprognostic (3.86e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (6.41e-4)" "unprognostic (7.27e-3)" "unprognostic (2.89e-2)" "unprognostic (9.89e-2)" "unprognostic (4.22e-3)" "unprognostic (1.25e-1)" "unprognostic (4.21e-3)" "unprognostic (7.00e-2)" "unprognostic (3.95e-2)" "unprognostic (3.62e-2)" "unprognostic (1.43e-1)" "unprognostic (3.15e-1)" "unprognostic (2.16e-1)" 52.3 117.5 25.0 9.7 24.3 3.1 53.5 24.4 32.2 74.6 34.4 44.6 9.4 78.0 22.5 17.7 84.6 28.8 90.8 26.1 27.9 110.1 43.9 38.6 9.6 30.3 29.1 337.3 120.6 49.5 74.9 45.8 24.8 63.1 5.4 14.9 62.9 44.2 64.1 38.3 22.5 20.9 25.2 31.7 48.0 40.5 29.7 6.9 148.9 30.2 4.6 41.2 36.7 22.3 34.2 22.7 40.9 85.8 27.7 20.4 155.2 25.3 36.8 31.5 29.0 20.0 52.2 0.2 51.6 34.7 30.5 34.4 31.9 19.0 6.5 0.3 56.2 74.3 23.0 102.1 20.9 1.9 0.3 55.3 15.4 7.3 12.1 56.1 3.4 0.1 31.3 0.7 22.7 84.6 0.1 21.3 97.8 9.7 23.1 37.5 36.3 0.2 57.4 31.9 18.1 61.3 28.6 150.9 59.2 102.8 14.0 63.9 8.6 33.3 35.6 10.6 10.0 0.2 0.2 0.3 19.5 0.2 33.7 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 1.3 0.0 0.0 25.0 24.3 24.4 32.2 26.1 27.9 30.3 29.1 24.8 25.2 29.7 22.3 10.4 9.6 20.4 45.7 1.1 8.4 22.8 11.7 19.9 35.8 27.0 38.7 52.4 27.1 10.0 53.3 2.1 64.7 2.5 1.5 52.8 15.9 1140.1 19.5 33.0 11.4 20.4 0.0 21.1 12.5 69.7 30.1 6.6 21.7 4.5 152.8 11.4 15.4 7.7 42.1 43.3 3.7 6.1 1.0 3.9 1994.5 77.0 3.4 14.2 9.4 0.7 87.0 0.0 23.1 3.1 7.6 2.0 74.1 0.1 8.8 7.1 20.3 7.8 11.6 13.1 29.9 27.0 572.7 57.0 4.3 6.7 86.5 1.4 114.0 3.3 10.2 INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.6;ovary: 104.4;testis: 95.3" "Cell type enhanced" "Detected in some" "Granulosa cells: 254.3;Syncytiotrophoblasts: 331.0;Theca cells: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.5;HEL: 4.5;SK-BR-3: 9.9;SuSa: 4.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "CAB000047: AB_322161, HPA019141: AB_1851789, HPA048834: " "unprognostic (8.90e-3)" "unprognostic (2.91e-2)" "unprognostic (2.82e-1)" "unprognostic (7.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.45e-1)" "unprognostic (3.57e-1)" "unprognostic (9.61e-3)" "unprognostic (4.15e-3)" "unprognostic (6.71e-2)" "unprognostic (3.73e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (4.85e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" 1.2 75.6 3.4 0.2 3.7 0.1 1.4 2.7 4.8 2.0 2.2 0.9 0.2 2.0 2.2 0.8 3.0 0.4 16.3 3.5 3.2 3.1 0.7 0.8 0.1 3.4 2.9 104.4 12.3 0.7 6.6 11.3 3.5 3.1 0.0 1.9 1.5 1.1 0.8 2.1 0.4 0.4 2.5 0.4 0.7 95.3 3.4 0.0 3.3 0.0 0.0 1.0 1.8 3.0 0.4 0.2 0.0 1.9 0.6 0.1 3.5 0.3 0.2 0.5 0.2 0.3 3.2 0.0 0.2 0.7 0.5 2.0 0.2 0.5 0.0 0.0 0.6 4.5 1.8 2.4 0.3 0.0 0.0 0.6 0.8 0.0 0.5 1.4 0.0 0.0 2.8 0.0 0.0 2.3 0.0 0.1 1.2 0.1 0.9 0.1 0.2 0.0 0.5 0.2 0.3 0.8 1.1 9.9 0.3 4.9 0.5 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 2.7 4.8 3.5 3.2 3.4 2.9 3.5 2.5 3.4 3.0 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.8 0.0 2.7 0.3 0.3 2.2 0.0 0.1 7.3 2.1 11.8 0.0 0.0 0.0 2.8 0.8 0.5 0.5 0.2 0.0 0.0 5.9 8.9 35.5 1.2 0.0 0.5 0.0 254.3 0.7 0.1 2.6 6.7 6.9 0.0 0.0 0.3 0.0 5.0 4.1 0.2 0.0 0.0 0.0 3.7 0.0 1.0 0.4 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.5 3.4 0.6 0.0 0.0 331.0 0.0 75.6 0.0 0.0 STK11IP "KIAA1898, LIP1, LKB1IP, STK11IP1" ENSG00000144589 "Serine/threonine kinase 11 interacting protein" Q8N1F8 2 219597857-219616451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 15.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036837, HPA036838, HPA053192" Approved Enhanced Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA036837: AB_10969754, HPA036838: AB_10672100, HPA053192: AB_2682075" "unprognostic (3.37e-1)" "unprognostic (1.33e-1)" "unprognostic (3.51e-1)" "unprognostic (1.97e-1)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (1.22e-3)" "unprognostic (8.36e-2)" "unprognostic (9.36e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.63e-4)" "unprognostic (9.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-3)" "unprognostic (9.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" 7.6 10.0 12.0 9.5 12.4 19.5 7.1 11.3 13.8 9.2 12.6 9.8 9.2 9.2 15.0 9.6 10.4 9.5 8.0 12.4 10.6 11.2 5.9 9.3 14.0 12.0 11.9 24.5 9.5 7.5 21.5 8.2 12.3 9.9 7.8 12.3 8.1 6.5 5.8 18.4 10.0 8.3 10.0 15.1 8.6 31.2 12.0 19.5 11.1 4.3 11.1 9.0 8.3 11.8 10.1 15.4 16.1 11.0 5.6 9.9 16.5 8.7 7.6 13.9 11.7 14.3 16.7 5.8 8.7 8.4 12.6 24.4 7.7 18.7 10.3 8.7 11.7 15.1 17.2 11.6 7.4 15.9 38.2 9.6 16.5 11.7 5.9 14.2 8.6 9.7 11.4 8.5 7.9 19.7 9.3 19.6 16.2 4.8 8.4 17.5 5.9 4.5 13.8 15.8 10.6 16.8 5.7 13.8 12.0 12.9 8.8 15.3 6.5 15.0 12.6 14.5 8.6 9.4 4.5 10.8 11.4 8.7 9.5 1.5 4.3 5.3 2.6 5.8 2.1 1.7 1.2 2.1 7.7 1.2 1.0 1.0 1.4 3.7 6.5 15.1 2.1 2.6 12.0 12.4 11.3 13.8 12.4 10.6 12.0 11.9 12.3 10.0 12.0 11.8 3.5 6.4 6.7 12.4 3.9 2.3 2.1 6.3 1.2 7.8 5.1 5.5 3.6 1.5 7.8 7.3 18.8 10.0 10.3 14.6 1.9 5.0 14.0 11.9 4.0 4.6 13.1 6.9 10.7 6.5 5.6 5.3 17.3 5.8 12.7 29.7 4.2 3.3 8.4 11.8 8.0 8.8 6.1 8.6 5.7 30.9 25.4 8.9 3.6 8.4 7.0 4.9 4.1 8.5 7.4 4.2 3.3 14.7 2.8 1.7 5.4 2.7 19.9 12.6 13.1 3.2 4.9 18.5 13.8 3.5 2.7 16.1 4.5 5.4 8.8 2.8 SLC4A3 "AE3, SLC2C" ENSG00000114923 "Solute carrier family 4 member 3" P48751 2 219627394-219641980 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 283.1;ovary: 124.1" "Group enriched" "Detected in many" 9 "Cardiomyocytes: 207.1;Horizontal cells: 558.6" "Cancer enhanced" "Detected in all" "glioma: 13.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34 "myeloid DC: 1.4;plasmacytoid DC: 5.8" "Lineage enriched" "Detected in single" 54 "dendritic cells: 5.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063498 Approved Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA063498: AB_2685025" "unprognostic (9.49e-2)" "unprognostic (5.72e-3)" "unprognostic (8.92e-4)" "unprognostic (1.77e-2)" "unprognostic (6.61e-3)" "unprognostic (1.47e-1)" "unprognostic (2.60e-1)" "unprognostic (2.39e-2)" "unprognostic (4.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-1)" "unprognostic (8.15e-3)" "unprognostic (1.97e-1)" "unprognostic (3.27e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.12e-4)" 6.3 16.7 36.1 1.0 36.6 0.4 3.9 21.2 32.1 11.4 6.3 2.9 0.7 15.3 2.7 3.2 9.3 2.3 283.1 31.7 34.5 9.3 0.3 1.6 0.9 44.1 20.7 124.1 3.9 7.7 41.4 2.7 43.1 10.4 0.2 13.0 3.8 5.3 0.9 2.0 1.1 3.7 10.6 3.3 2.7 14.2 32.7 1.0 2.5 0.6 0.6 2.6 4.7 18.0 6.9 0.2 2.3 6.8 0.4 0.4 4.9 4.1 4.2 5.4 3.8 4.8 3.8 0.0 1.6 1.5 9.3 3.8 1.2 7.3 1.6 0.0 1.0 0.0 0.1 0.1 1.1 0.1 0.3 3.1 7.0 0.0 2.1 13.4 0.0 0.0 0.3 0.0 1.6 2.3 0.0 0.0 3.8 0.2 5.5 0.0 0.0 0.0 3.7 1.5 1.3 6.7 2.7 6.9 3.7 7.2 0.7 1.7 0.0 3.4 6.0 0.0 3.3 0.0 0.0 0.0 2.7 0.0 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 36.1 36.6 21.2 32.1 31.7 34.5 44.1 20.7 43.1 10.6 32.7 18.0 0.3 0.0 0.0 19.2 0.2 0.3 0.7 1.5 0.0 14.4 2.2 4.8 207.1 0.0 0.8 1.8 0.0 11.4 13.5 0.0 1.9 3.0 2.3 0.9 3.5 1.8 0.0 0.0 11.5 1.7 3.0 10.4 0.0 1.4 0.0 38.3 0.0 0.0 1.8 558.6 32.7 0.0 0.0 0.3 5.6 25.6 15.2 1.1 0.0 3.7 1.3 7.6 0.0 3.5 0.6 1.1 0.0 22.6 0.0 0.4 0.0 0.3 0.2 7.5 6.6 3.9 3.5 0.6 1.2 0.0 0.9 13.8 0.1 8.7 0.0 0.1 EPHA4 "Hek8, TYRO1" ENSG00000116106 "EPH receptor A4" P54764 2 221418027-221574202 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 39.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 317.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 14.9" "Group enriched" "Detected in many" 6 "cerebral cortex: 23.8;hippocampal formation: 20.9" "Group enriched" "Detected in many" 9 "basophil: 1.6;gdT-cell: 1.7;MAIT T-cell: 1.7;memory B-cell: 1.3;memory CD4 T-cell: 2.5;memory CD8 T-cell: 1.7;naive B-cell: 1.2;naive CD4 T-cell: 1.0;NK-cell: 3.5;T-reg: 1.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 77.0;ASC diff: 33.9;CACO-2: 59.3;U-2197: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB028368 Enhanced NA NA 9300000 "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "CAB028368: AB_2099353" "unprognostic (1.28e-1)" "unprognostic (5.87e-2)" "unprognostic (2.28e-1)" "unprognostic (2.46e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (7.05e-4)" "unprognostic (1.80e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (1.12e-1)" "unprognostic (2.85e-2)" "prognostic favorable (5.67e-4)" "unprognostic (3.12e-2)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (8.66e-2)" 7.8 1.6 0.0 1.9 3.9 3.7 3.9 0.0 23.8 4.5 39.7 4.6 1.0 6.4 2.8 4.8 4.9 3.1 17.4 20.9 0.0 4.8 0.8 3.6 2.7 0.0 1.5 11.1 1.1 1.9 0.6 1.6 0.0 5.3 4.5 4.2 2.6 6.1 2.7 12.9 2.8 8.0 0.0 3.4 2.3 11.7 3.7 3.8 9.5 4.0 3.2 3.6 3.5 0.0 2.6 2.4 77.0 0.0 33.9 20.9 0.1 18.2 8.3 16.9 6.2 59.3 0.9 0.0 0.1 26.7 0.0 7.0 12.3 0.1 7.0 9.7 6.4 0.0 0.9 0.0 0.9 0.0 1.4 8.5 4.2 5.3 0.1 10.3 14.9 0.0 0.0 0.0 4.4 9.5 0.2 0.0 5.6 5.9 1.7 0.1 8.5 0.0 25.8 4.3 13.2 0.0 6.2 1.3 1.3 6.2 2.9 0.0 0.0 1.7 3.2 38.4 1.0 0.0 0.1 0.0 6.9 0.0 3.6 1.6 0.0 0.0 1.7 0.0 1.7 1.3 2.5 1.7 0.0 1.2 1.0 0.2 0.1 3.5 0.0 0.1 1.2 0.4 0.0 3.9 0.0 23.8 20.9 0.0 0.0 1.5 0.0 0.0 3.7 0.0 36.3 0.0 6.4 51.9 8.2 6.1 0.7 9.7 2.8 9.8 4.3 6.0 31.6 7.2 13.7 9.2 0.0 0.1 12.2 4.7 7.9 0.2 3.9 1.9 5.7 26.3 3.5 0.0 317.9 0.2 0.0 5.1 4.6 5.2 1.3 9.0 20.0 0.4 0.3 1.7 68.8 12.8 8.2 0.0 1.5 5.8 1.2 0.9 7.2 70.3 0.2 7.2 3.1 8.0 7.9 30.9 3.6 8.6 2.1 1.4 0.1 1.7 4.5 3.2 0.0 3.6 10.2 10.0 1.9 4.1 12.5 0.0 5.4 11.3 6.6 2.4 PAX3 "HUP2, WS1" ENSG00000135903 "Paired box 3" P23760 2 222199887-222298998 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Deafness, Disease variant, Proto-oncogene, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;salivary gland: 4.8;skeletal muscle: 3.6;skin 1: 2.9" "Group enriched" "Detected in some" 4 "Early spermatids: 14.4;Late spermatids: 34.8;Melanocytes: 33.8;Skeletal myocytes: 12.8" "Cancer enriched" "Detected in some" 24 "melanoma: 20.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 9.0;BJ hTERT+ SV40 Large T+ RasG12V: 10.6;HBF TERT88: 8.0;RH-30: 17.5;SK-MEL-30: 29.1" "Group enriched" "Detected in some" 7 "cerebellum: 3.4;midbrain: 1.4;pons and medulla: 1.3" "Region enhanced" "Detected in many" "midbrain: 7.7" "HPA063659, HPA069000" Enhanced Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA063659: AB_2685080, HPA069000: AB_2686067" "unprognostic (2.57e-2)" "unprognostic (1.48e-2)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.61e-2)" "unprognostic (3.70e-1)" "unprognostic (6.18e-2)" "unprognostic (1.41e-1)" "unprognostic (2.26e-1)" "unprognostic (9.70e-2)" 0.5 0.0 0.4 0.0 0.1 0.0 1.0 4.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.3 1.9 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 4.8 0.0 3.6 2.9 0.0 0.0 2.0 0.0 0.0 1.1 1.2 0.0 0.0 0.8 0.1 0.0 0.1 5.5 0.0 0.0 4.9 0.0 0.0 0.0 0.0 6.0 6.5 9.0 10.6 0.0 0.7 0.0 0.0 4.4 0.2 0.0 0.0 0.0 8.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 6.9 0.1 0.0 0.0 0.0 17.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 29.1 7.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.5 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 4.6 0.1 0.0 0.1 3.3 1.9 2.8 2.0 1.2 5.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.2 0.0 0.0 2.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.8 34.8 0.9 0.1 33.8 1.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.4 5.6 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.0 AC010980.1 ENSG00000288658 "Novel protein, ortholog of Gm2102 (M. musculus)" 2 222317242-222320208 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "brain: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.8;NB-4: 1.8;REH: 2.5;SCLC-21H: 3.7;SH-SY5Y: 1.7;SuSa: 1.7" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" 0.0 1.2 2.8 0.3 2.7 0.1 0.2 0.1 7.1 0.1 0.0 0.2 0.2 0.3 0.6 0.3 0.2 0.0 0.6 6.3 2.1 0.3 0.0 0.1 0.0 1.4 2.2 0.0 0.2 0.9 0.1 1.1 0.0 0.2 0.1 0.1 0.4 0.2 0.2 0.1 0.5 0.8 0.0 0.1 0.7 3.1 0.1 0.8 0.3 0.0 0.3 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.4 0.0 1.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 2.5 0.9 0.0 0.5 0.0 3.7 1.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.1 7.1 6.3 2.1 1.4 2.2 1.1 0.8 3.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SGPP2 "FLJ39004, SPP2" ENSG00000163082 "Sphingosine-1-phosphate phosphatase 2" Q8IWX5 2 222424543-222562621 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.0;Excitatory neurons: 43.5;Glandular and luminal cells: 54.2;Microglial cells: 48.7;Urothelial cells: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 16.2;EFO-21: 13.0;hTCEpi: 52.6;RPTEC TERT1: 59.0;SCLC-21H: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (2.56e-3)" "unprognostic (1.79e-1)" "unprognostic (8.50e-2)" "unprognostic (2.97e-2)" "unprognostic (1.24e-3)" "unprognostic (5.22e-2)" "unprognostic (9.16e-2)" "unprognostic (2.31e-2)" "unprognostic (3.54e-3)" "unprognostic (6.24e-2)" "prognostic favorable (1.28e-4)" "unprognostic (3.25e-2)" "unprognostic (2.19e-1)" "unprognostic (1.74e-2)" "unprognostic (2.69e-2)" 2.8 6.1 11.1 4.0 12.8 1.4 5.3 15.0 15.3 13.3 2.1 17.3 17.3 2.7 3.8 21.4 13.2 11.5 5.2 11.0 13.7 16.4 0.4 8.0 3.9 17.9 10.9 0.5 3.1 26.8 5.9 0.1 17.6 1.5 18.1 3.6 7.9 7.6 0.8 22.4 18.2 1.4 9.7 1.0 25.1 1.6 15.2 5.3 21.2 0.0 15.2 22.3 10.0 9.8 1.4 1.1 0.4 1.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 16.2 0.6 13.0 0.0 0.2 0.3 0.2 0.1 0.0 0.3 4.6 1.0 0.4 0.0 0.0 1.7 0.8 0.0 52.6 0.0 0.2 0.0 0.0 0.7 0.3 0.6 0.0 0.8 0.4 1.2 0.5 10.6 0.4 0.7 0.4 0.6 59.0 3.7 16.5 0.6 0.0 1.9 0.1 0.8 0.2 0.1 0.0 0.2 0.5 0.6 0.5 0.5 0.4 1.0 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 11.1 12.8 15.0 15.3 11.0 13.7 17.9 10.9 17.6 9.7 15.2 9.8 0.1 3.2 11.5 1.3 2.2 3.7 4.4 29.1 4.6 5.3 1.6 1.5 6.9 7.2 26.2 12.9 6.2 0.1 0.6 20.2 1.9 14.5 9.7 33.0 4.8 1.5 1.2 0.0 43.5 1.8 0.3 1.4 25.5 54.2 0.0 0.4 0.0 0.1 0.2 1.7 15.8 5.5 14.2 0.0 1.1 3.7 0.6 0.8 0.0 48.7 0.1 0.7 1.0 2.5 1.1 9.3 16.3 0.4 2.3 7.5 13.1 0.5 20.4 5.9 0.0 2.1 1.7 3.1 1.0 26.3 14.3 2.5 2.5 0.3 9.9 39.4 FARSB "FARSLB, FRSB, PheHB" ENSG00000116120 "Phenylalanyl-tRNA synthetase subunit beta" Q9NSD9 2 222566899-222656092 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036677, HPA036678, HPA061398" Enhanced Supported Nucleoplasm,Cytosol NA NA 28000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA036677: AB_2675242, HPA036678: AB_10673504, HPA061398: AB_2684504" "unprognostic (9.95e-3)" "unprognostic (1.86e-3)" "unprognostic (7.02e-2)" "unprognostic (7.42e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.45e-10)" "unprognostic (8.89e-3)" "unprognostic (4.51e-2)" "unprognostic (3.63e-2)" "unprognostic (5.25e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (3.21e-5)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (1.25e-4)" 12.8 10.9 9.5 7.6 10.0 8.0 12.8 10.4 11.3 13.1 6.5 14.7 9.1 13.5 6.5 20.7 11.9 3.9 16.7 10.2 10.7 11.8 14.1 9.4 7.4 9.6 9.4 14.3 15.6 8.0 13.2 5.0 10.8 11.2 11.1 10.0 10.4 6.1 31.9 14.9 10.8 8.1 8.4 9.7 13.9 13.5 9.9 7.7 9.7 13.2 8.3 13.1 13.7 9.4 31.1 17.8 20.7 27.2 18.0 26.3 31.0 31.0 19.2 29.4 23.9 45.3 16.6 15.3 22.7 22.6 24.7 25.8 39.7 34.7 43.0 22.8 20.7 35.1 18.9 28.8 27.9 51.9 14.0 17.6 27.0 33.9 51.2 10.5 28.3 26.4 53.5 30.3 36.1 28.9 31.2 29.2 26.6 37.0 22.0 30.2 49.4 49.8 24.5 19.9 33.4 11.2 12.9 22.4 27.6 24.7 20.9 21.3 15.8 25.5 21.1 37.8 38.5 14.8 15.5 54.5 20.8 34.0 27.2 0.5 7.6 1.2 9.6 9.4 14.3 15.1 12.8 11.9 14.4 12.7 16.4 14.2 0.9 17.4 11.3 7.2 12.5 13.7 9.5 10.0 10.4 11.3 10.2 10.7 9.6 9.4 10.8 8.4 9.9 9.4 10.2 6.4 6.4 21.2 25.2 12.4 19.5 32.7 19.4 17.9 16.3 18.0 28.6 5.7 18.5 22.0 4.2 37.0 7.5 18.1 35.2 24.7 57.5 17.3 15.8 13.3 20.9 24.2 50.2 30.4 43.3 18.0 32.6 18.6 5.1 21.8 7.5 17.8 27.4 3.3 56.7 19.9 20.3 10.1 9.7 73.1 15.2 11.8 7.2 26.2 11.3 13.2 15.5 38.7 38.2 22.8 11.3 19.9 27.3 18.1 9.9 31.0 16.8 19.5 6.6 17.6 34.4 67.4 33.7 28.8 14.2 22.2 16.9 24.3 45.8 14.3 MOGAT1 "DGAT2L, DGAT2L1, MGAT1" ENSG00000124003 "Monoacylglycerol O-acyltransferase 1" Q96PD6 2 222671658-222709930 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "gallbladder: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Breast glandular cells: 7.2;Cholangiocytes: 7.2;Endometrial ciliated cells: 3.9;Exocrine glandular cells: 5.1;Glandular and luminal cells: 4.9;Hepatocytes: 3.2" "Cancer enhanced" "Detected in some" "pancreatic cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA049944, HPA076308" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Mammary glandular cells - Lactation" Cytosol "Endoplasmic reticulum" "HPA049944: AB_2680964, HPA076308: " "unprognostic (6.32e-2)" "unprognostic (2.38e-1)" "unprognostic (1.15e-1)" "unprognostic (1.41e-1)" "unprognostic (4.28e-3)" "unprognostic (4.39e-2)" "unprognostic (4.32e-2)" "unprognostic (9.44e-2)" "unprognostic (1.91e-1)" "unprognostic (8.59e-2)" "unprognostic (3.07e-3)" "unprognostic (4.99e-2)" "unprognostic (3.89e-1)" "unprognostic (9.03e-3)" 0.9 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.6 0.1 0.0 16.8 0.4 0.1 0.1 0.8 3.1 0.4 0.0 0.1 0.6 0.0 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.1 0.5 0.1 0.4 0.6 0.0 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.1 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.4 7.2 0.3 0.7 7.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.9 3.9 0.6 0.1 0.0 0.0 2.5 5.1 0.0 0.1 0.0 4.9 0.0 0.2 0.0 3.2 0.9 0.0 1.9 0.0 0.0 0.3 0.3 0.1 0.0 1.3 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.9 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 ACSL3 "ACS3, FACL3, PRO2194" ENSG00000123983 "Acyl-CoA synthetase long chain family member 3" O95573 2 222860942-222944639 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 172.1" "Cell type enhanced" "Detected in all" "Horizontal cells: 523.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 410.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011315, HPA071021" Approved Approved "Nucleoli,Nucleoli rim,Lipid droplets" NA NA 37000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli, Nucleoli rim" "Lipid droplets" "HPA011315: AB_1848344, HPA071021: AB_2686335" "unprognostic (1.87e-1)" "unprognostic (5.64e-2)" "unprognostic (2.36e-1)" "unprognostic (9.35e-3)" "unprognostic (7.53e-2)" "unprognostic (2.07e-2)" "prognostic unfavorable (2.75e-4)" "prognostic unfavorable (8.78e-4)" "unprognostic (3.90e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-1)" "unprognostic (2.72e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" 25.2 19.8 22.2 17.5 24.7 27.7 90.8 21.9 29.5 18.4 8.8 27.0 22.2 12.6 24.8 36.1 11.0 16.7 14.8 22.9 26.7 24.3 30.9 20.6 12.3 20.9 26.0 10.8 16.7 172.1 10.0 28.0 22.4 66.1 25.5 32.2 45.4 16.2 25.3 14.9 16.0 14.5 27.5 10.5 50.6 23.3 35.3 19.8 23.8 15.2 14.2 33.5 20.6 24.5 49.7 77.0 118.3 121.9 42.1 121.3 35.0 61.0 159.5 70.5 139.8 75.0 126.4 24.0 33.8 51.9 147.2 143.9 20.4 121.3 76.0 44.0 50.1 55.8 52.2 68.0 91.0 36.2 26.6 60.0 180.7 120.0 163.6 34.7 65.6 39.8 109.6 83.1 78.1 104.8 70.4 42.5 59.9 102.9 42.4 40.0 85.4 39.7 80.8 198.2 57.3 49.3 36.0 79.5 410.5 67.5 49.8 64.8 58.0 43.9 76.2 41.5 41.0 30.0 17.2 81.3 40.7 26.0 140.0 10.7 14.0 20.0 18.0 16.0 17.5 10.5 11.2 13.6 15.2 11.1 16.0 14.9 15.6 16.6 17.2 20.8 9.5 17.5 22.2 24.7 21.9 29.5 22.9 26.7 20.9 26.0 22.4 27.5 35.3 24.5 73.1 35.3 70.8 110.4 29.6 46.5 101.8 97.5 55.2 101.9 89.9 62.9 57.2 28.6 93.8 36.8 77.2 43.7 45.0 46.6 7.9 32.7 59.2 68.9 39.6 41.4 20.9 35.8 91.0 31.1 10.7 56.6 81.1 100.7 27.3 25.3 32.2 52.7 37.4 523.3 124.2 36.0 99.7 49.0 62.7 27.1 26.1 75.3 48.0 69.3 32.1 184.7 20.6 149.3 120.1 37.3 41.3 35.7 24.6 109.4 17.5 14.6 80.3 55.6 46.0 52.8 68.2 49.7 45.3 108.6 48.7 60.6 32.4 52.0 50.7 117.1 KCNE4 MiRP3 ENSG00000152049 "Potassium voltage-gated channel subfamily E regulatory subunit 4" Q8WWG9 2 223051814-223198399 "Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 37.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 32.3;Melanocytes: 32.0;Sertoli cells: 118.3;Smooth muscle cells: 128.3" "Cancer enhanced" "Detected in all" "breast cancer: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "AN3-CA: 164.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA011420 Approved Approved "Nuclear bodies,Microtubules" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Microtubules "Nuclear bodies" "HPA011420: AB_1079170" "unprognostic (1.23e-1)" "unprognostic (2.02e-3)" "prognostic unfavorable (9.42e-5)" "unprognostic (2.17e-2)" "unprognostic (7.56e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.06e-2)" "unprognostic (3.32e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" "unprognostic (6.24e-3)" "unprognostic (9.08e-3)" 13.3 3.4 7.7 11.0 6.9 0.5 6.9 6.0 11.2 5.0 5.8 8.0 1.3 30.7 2.3 5.1 7.9 20.3 13.5 8.0 6.9 7.5 5.1 3.1 5.7 9.5 8.1 12.3 10.3 1.8 10.3 6.7 9.3 4.4 2.0 3.3 2.7 5.5 5.4 3.2 3.6 37.5 6.9 4.5 12.5 1.1 7.5 0.7 9.4 3.2 1.1 10.7 3.8 8.0 0.0 0.8 0.0 164.3 36.6 3.7 0.2 4.0 3.8 0.8 1.8 0.0 0.2 0.0 0.0 2.5 5.8 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.3 0.0 4.5 0.0 0.1 6.3 0.0 5.5 0.0 0.0 0.0 0.1 0.0 0.2 6.7 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.1 0.1 0.4 6.4 0.1 12.1 0.7 0.1 0.0 0.0 3.8 0.1 3.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.7 6.9 6.0 11.2 8.0 6.9 9.5 8.1 9.3 6.9 7.5 8.0 8.2 0.0 2.2 4.2 0.0 3.8 0.4 0.2 0.0 0.1 1.8 0.4 4.9 0.0 1.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.8 16.3 19.8 4.8 0.0 0.0 0.0 0.2 32.3 9.2 0.6 3.8 0.4 3.9 0.2 0.1 3.3 0.3 0.0 2.0 0.0 5.8 0.3 21.1 1.0 32.0 5.6 0.0 6.1 0.0 1.0 0.0 0.4 0.1 17.0 0.4 1.4 0.0 0.0 3.7 0.7 118.3 1.7 128.3 0.1 0.2 0.4 3.1 0.3 0.6 0.1 0.2 1.8 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 212.4;Enteroendocrine cells: 283.4;Inhibitory neurons: 109.9;Ionocytes: 138.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.3;HSkMC: 45.9;hTERT-RPE1: 46.5;SCLC-21H: 47.6;SH-SY5Y: 20.7;WM-115: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 9.2 360.1 49.2 30.2 78.4 0.4 0.5 17.1 54.7 1.5 2.2 10.6 47.7 3.5 0.4 0.6 0.2 4.0 1.7 21.7 426.2 0.6 0.2 3.3 0.4 118.3 195.4 6.1 28.3 0.5 269.0 1.1 250.9 3.5 13.0 40.6 0.3 1.2 0.3 1.0 21.3 12.8 77.4 0.2 17.9 0.2 130.7 0.1 6.4 0.8 0.1 0.8 1.3 30.3 0.0 3.1 10.3 8.5 2.3 53.3 0.2 0.5 2.0 4.0 10.1 0.4 1.0 0.0 0.9 0.7 6.2 0.2 0.2 0.0 5.0 0.1 0.5 0.0 0.6 0.0 0.5 0.7 4.6 45.9 0.2 5.8 2.0 46.5 0.0 0.0 0.2 0.4 5.1 0.3 0.0 0.2 7.3 0.1 0.2 0.0 0.3 0.3 0.9 0.1 47.6 20.7 0.0 0.5 2.5 1.6 0.0 0.1 0.1 5.4 2.2 0.2 3.6 0.1 0.0 0.3 1.6 0.1 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 78.4 17.1 54.7 21.7 426.2 118.3 195.4 250.9 77.4 130.7 30.3 0.0 6.4 0.0 12.7 0.0 0.0 0.4 2.8 0.0 212.4 0.0 0.0 0.1 0.0 1.3 0.0 2.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 6.7 283.4 0.0 27.7 0.2 0.0 2.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 8.4 109.9 14.7 138.4 0.3 0.3 0.0 0.6 0.0 1.8 3.7 0.0 11.6 0.0 34.2 8.2 14.8 6.2 0.4 0.0 2.1 0.1 0.1 0.7 14.6 0.0 1.8 1.7 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.5 0.8 AP1S3 ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223751686-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 52.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Cytotrophoblasts: 48.2;Pancreatic endocrine cells: 44.2;Urothelial cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.9;dendritic cells: 4.0;granulocytes: 4.9" "Cell line enhanced" "Detected in many" "CACO-2: 151.1;RPTEC TERT1: 56.8;RT4: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" 0.7 0.8 3.4 3.3 3.2 4.0 2.1 3.9 3.5 2.2 0.5 2.7 5.3 0.9 52.8 4.8 2.3 5.2 0.5 2.8 3.0 5.6 1.4 4.7 4.2 2.0 1.6 0.5 2.4 3.8 1.1 6.6 1.5 2.9 2.6 5.7 1.6 5.4 0.9 1.9 5.0 0.7 1.1 2.8 9.8 0.9 3.2 1.6 14.4 0.3 5.2 8.1 1.2 2.1 28.7 17.7 2.4 12.0 1.5 0.6 13.5 11.5 2.4 4.9 4.2 151.1 21.8 11.0 8.0 1.7 5.8 43.8 6.4 30.3 6.8 15.3 8.9 1.2 33.7 15.7 0.6 3.4 1.3 0.6 31.2 9.1 30.1 11.2 3.4 5.8 1.8 2.9 2.9 12.3 0.6 0.9 3.8 32.8 15.5 4.3 0.1 4.5 56.8 52.1 7.4 2.1 5.4 11.8 3.8 6.1 5.0 6.3 2.0 1.6 4.6 3.1 9.2 10.2 9.0 28.2 4.4 2.0 6.0 4.9 0.5 0.3 0.6 0.4 0.5 4.9 0.4 0.4 1.2 2.7 0.4 0.5 1.8 0.6 0.2 4.0 1.0 0.4 3.4 3.2 3.9 3.5 2.8 3.0 2.0 1.6 1.5 1.1 3.2 2.1 0.4 35.3 6.7 8.8 24.2 4.2 32.6 15.3 4.0 3.3 4.3 1.8 1.7 0.0 15.8 11.0 64.6 48.2 13.6 3.6 9.8 17.5 0.2 8.1 2.1 2.1 2.4 0.0 19.3 18.1 3.4 3.5 11.7 26.1 3.8 0.8 0.7 0.4 4.7 6.7 9.6 3.6 16.2 1.6 38.1 0.0 0.3 7.5 3.6 4.7 7.4 1.9 6.2 10.6 4.0 44.2 4.6 0.0 10.7 26.6 5.4 4.5 10.3 5.9 0.0 1.1 1.8 0.3 1.9 6.3 4.1 13.1 6.9 1.0 4.7 69.6 WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA050603: AB_2681188, HPA079597: " "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (7.62e-2)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (2.63e-2)" "unprognostic (7.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (3.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (7.55e-2)" 18.6 13.2 9.3 18.0 9.5 48.5 14.4 9.3 12.0 20.5 11.2 20.4 15.6 22.6 19.8 14.4 20.5 17.5 11.7 9.2 10.7 14.8 18.0 18.4 23.3 11.0 10.2 20.2 14.1 19.8 8.7 27.4 11.4 16.2 20.1 15.9 13.5 12.8 11.4 13.5 15.9 19.6 9.7 21.2 19.8 10.9 10.5 15.9 22.1 12.6 18.9 17.9 13.7 11.1 27.9 19.3 34.9 27.2 46.4 44.0 43.7 34.7 48.3 37.5 30.4 81.4 25.0 7.7 30.8 60.6 47.3 19.2 18.7 52.3 40.4 15.6 15.8 19.2 31.9 59.2 36.4 15.2 15.8 39.0 37.9 46.3 71.0 62.4 63.9 16.2 34.3 23.4 44.4 26.8 6.5 11.1 34.5 20.7 16.6 25.3 44.8 8.6 28.4 47.7 29.6 15.7 20.7 19.2 90.9 41.6 12.5 38.1 70.9 74.9 25.7 13.5 18.0 28.8 4.6 21.4 36.3 32.9 26.2 4.4 21.5 8.1 13.7 29.0 16.6 14.1 9.7 13.5 14.8 11.7 10.0 9.5 10.3 24.0 25.7 3.0 9.7 17.6 9.3 9.5 9.3 12.0 9.2 10.7 11.0 10.2 11.4 9.7 10.5 11.1 40.0 16.0 9.3 22.5 22.0 12.5 14.5 19.9 17.1 14.0 11.8 7.6 7.7 12.8 24.4 16.5 8.4 22.6 25.5 36.4 9.8 12.9 0.8 23.2 30.7 34.1 10.3 11.2 28.7 17.2 11.2 21.4 29.6 36.5 17.7 12.5 16.8 25.7 17.9 28.6 28.1 15.2 8.2 26.3 17.2 2.4 14.6 24.4 35.6 27.2 25.6 13.9 24.7 33.7 39.8 18.0 24.4 23.7 21.8 16.6 16.0 14.4 29.9 10.9 6.6 13.1 26.7 3.8 8.8 24.4 15.5 19.0 21.1 15.0 21.8 28.7 MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: AB_10671521, HPA038148: AB_2675863" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (3.38e-2)" "unprognostic (3.00e-1)" "unprognostic (7.05e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.16e-2)" "unprognostic (3.32e-1)" "unprognostic (7.65e-2)" "unprognostic (8.33e-2)" "unprognostic (6.65e-2)" "prognostic favorable (2.02e-4)" "unprognostic (2.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-1)" 16.2 26.9 16.2 14.9 17.4 45.4 17.6 17.1 20.3 12.9 19.0 21.8 19.3 12.7 13.2 18.0 16.3 17.5 33.8 17.1 18.8 37.4 39.3 12.5 32.5 16.2 16.1 15.2 17.4 19.7 11.6 20.0 16.8 15.3 22.9 10.0 16.1 13.2 42.6 15.7 17.9 14.4 17.5 17.8 16.2 18.2 17.8 21.4 16.2 40.6 26.5 17.1 11.5 17.9 27.3 22.6 33.1 38.3 30.6 36.1 52.4 30.0 33.6 48.0 50.4 81.0 33.4 41.1 31.9 26.0 43.9 35.3 54.5 41.5 44.1 39.0 38.7 45.0 24.0 64.4 44.9 50.0 33.1 42.5 50.9 29.1 38.7 40.4 47.8 41.4 43.7 31.6 38.9 31.9 37.8 62.9 49.4 54.8 23.6 43.8 40.6 25.5 64.3 22.8 45.0 25.7 22.0 49.0 74.8 48.6 41.4 71.2 31.5 31.8 24.7 27.3 24.5 34.5 25.9 58.7 32.2 47.4 35.6 55.7 44.5 35.3 28.5 44.8 36.5 45.9 30.4 34.4 42.2 42.3 36.5 32.3 58.1 33.8 41.2 33.9 33.7 36.3 16.2 17.4 17.1 20.3 17.1 18.8 16.2 16.1 16.8 17.5 17.8 17.9 11.7 6.4 13.1 3.9 31.3 17.8 27.4 52.6 23.9 17.3 15.6 17.4 10.4 27.1 30.0 27.6 0.0 95.3 29.5 25.0 82.2 45.3 8.1 17.1 22.3 20.7 13.1 26.5 6.5 35.1 64.8 24.9 14.3 26.6 18.4 22.0 20.7 51.5 46.6 11.8 6.9 22.0 48.8 33.3 14.5 7.9 18.0 25.4 33.8 4.7 35.3 16.5 20.6 7.5 9.7 37.2 18.1 18.0 24.8 21.7 23.6 106.1 25.6 12.7 19.7 14.2 18.8 41.1 56.3 22.8 16.6 48.7 20.9 40.9 28.3 37.6 SERPINE2 "GDN, nexin, PI7, PN1, PNI" ENSG00000135919 "Serpin family E member 2" P07093 2 223975045-224039318 "Plasma proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein, Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 1091.9" "Cell type enriched" "Detected in many" 8 "Granulosa cells: 4466.0" "Cancer enriched" "Detected in all" 9 "melanoma: 271.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "naive CD4 T-cell: 12.9;naive CD8 T-cell: 6.8;NK-cell: 23.2" "Group enriched" "Detected in many" 15 "NK-cells: 23.2;T-cells: 12.9" "Cell line enhanced" "Detected in many" "BJ: 1492.9;fHDF/TERT166: 6425.1;SK-MEL-30: 2966.9;WM-115: 2183.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000277 Approved "Golgi apparatus" "Secreted in female reproductive system" NA NA 910000 "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "HPA000277: " "unprognostic (1.73e-1)" "unprognostic (7.08e-3)" "unprognostic (8.49e-2)" "unprognostic (7.78e-3)" "unprognostic (2.57e-3)" "unprognostic (5.57e-2)" "unprognostic (1.49e-2)" "unprognostic (7.43e-3)" "unprognostic (4.41e-1)" "unprognostic (7.12e-2)" "unprognostic (7.56e-3)" "unprognostic (2.40e-1)" "unprognostic (1.97e-3)" "unprognostic (1.23e-2)" "unprognostic (1.31e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.48e-5)" 28.0 19.8 120.3 75.7 125.9 6.5 14.3 128.6 158.7 28.1 71.1 22.7 28.2 17.4 5.6 36.2 20.8 46.0 100.0 115.9 145.9 39.3 10.8 14.5 30.9 158.1 152.6 145.6 8.5 3.4 8.7 1091.9 134.4 26.4 21.8 5.4 12.6 7.5 6.6 11.2 27.0 119.6 141.1 30.9 8.9 57.6 146.4 17.0 26.1 10.8 44.0 146.9 27.6 132.0 3.1 83.8 29.4 32.6 1172.5 438.7 4.4 1492.9 851.5 118.1 112.7 4.8 7.0 0.4 32.5 6425.1 188.0 5.0 3.5 102.5 101.0 0.6 26.8 16.6 49.9 22.7 57.7 12.8 1.5 128.3 68.5 342.0 505.6 304.6 9.0 5.4 0.5 1.9 412.1 4.5 2.3 3.9 56.2 31.8 92.3 10.3 25.2 64.5 1100.2 97.5 43.0 7.1 284.4 0.5 2966.9 385.2 1.2 6.4 1056.5 692.5 96.6 214.4 72.7 6.3 13.3 0.8 443.5 11.1 2183.6 0.0 0.0 0.0 0.7 0.0 0.5 0.8 0.6 0.6 0.0 1.2 12.9 6.8 0.5 23.2 0.0 0.2 0.7 2.7 120.3 125.9 128.6 158.7 115.9 145.9 158.1 152.6 134.4 141.1 146.4 132.0 13.5 0.0 1.1 233.1 3.1 23.3 16.0 132.2 351.7 5.3 7.9 8.5 5.3 0.0 4.6 7.3 0.0 106.1 11.3 19.5 11.7 13.0 2.6 5.3 17.7 20.9 24.0 23.1 86.1 33.2 524.3 556.7 5.6 5.9 2.5 4466.0 23.2 0.0 45.5 0.0 11.4 4.7 0.0 0.8 26.9 9.9 401.4 9.7 142.3 23.4 3.5 2.5 2.1 199.6 13.5 22.1 14.9 98.9 5.6 27.2 2.0 146.2 1.7 3.5 13.1 5.2 146.6 4.2 70.9 34.8 14.5 133.9 10.7 18.9 3.1 7.2 FAM124B FLJ22746 ENSG00000124019 "Family with sequence similarity 124 member B" Q9H5Z6 2 224378698-224402107 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 8.5" "Group enriched" "Detected in some" 4 "Adipocytes: 13.8;Endothelial cells: 10.8;Erythroid cells: 9.4;granulocytes: 4.5" "Cancer enriched" "Detected in many" 10 "testis cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 29.5;eosinophil: 17.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 7 "HUVEC TERT2: 103.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA070240 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Mitochondria "HPA070240: AB_2686238" "unprognostic (2.01e-1)" "unprognostic (1.83e-1)" "unprognostic (6.87e-3)" "unprognostic (2.49e-1)" "unprognostic (7.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.28e-2)" "unprognostic (5.78e-2)" "unprognostic (3.19e-1)" "unprognostic (1.85e-1)" "unprognostic (1.57e-1)" "unprognostic (3.36e-1)" "unprognostic (7.61e-3)" "unprognostic (1.36e-2)" "unprognostic (4.30e-1)" "unprognostic (2.25e-1)" "unprognostic (5.80e-3)" 5.2 0.5 1.4 1.1 1.2 4.7 4.3 1.4 1.7 1.5 0.9 0.9 1.0 1.6 0.3 1.4 1.2 1.2 1.8 1.3 1.6 0.6 1.9 2.3 0.7 1.8 1.7 0.4 0.4 2.4 0.2 8.5 1.5 0.5 1.0 0.2 0.8 0.5 1.2 1.8 1.0 2.3 1.6 0.5 0.6 0.3 1.7 1.1 1.0 4.6 0.7 1.5 1.4 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.5 0.1 0.0 0.0 0.0 15.0 0.0 0.1 0.0 0.0 0.0 103.4 0.0 4.8 0.2 0.0 0.1 0.0 0.1 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.7 7.5 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 29.5 3.0 17.2 0.2 2.3 0.0 0.0 0.7 0.0 7.9 0.0 0.0 0.0 0.1 5.4 0.8 0.0 2.5 1.1 1.4 1.2 1.4 1.7 1.3 1.6 1.8 1.7 1.5 1.6 1.7 1.1 13.8 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 1.2 0.3 0.2 10.8 0.0 9.4 0.2 0.0 0.1 0.4 0.0 0.8 4.5 0.0 2.2 0.4 0.4 0.0 0.2 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 1.0 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.1 0.1 0.0 0.0 CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 224.8" "Cell type enhanced" "Detected in all" "Late spermatids: 309.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002678 Supported NA NA 65000 "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "CAB002678: " "unprognostic (1.22e-2)" "unprognostic (2.35e-1)" "unprognostic (7.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.82e-1)" "unprognostic (7.03e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-3)" "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (4.86e-3)" "unprognostic (2.16e-2)" "unprognostic (8.74e-3)" "unprognostic (9.61e-2)" "unprognostic (1.87e-2)" 30.6 33.6 26.7 36.3 28.2 62.5 40.6 30.4 34.7 35.3 31.0 38.2 36.1 33.6 41.8 54.2 28.7 32.8 39.0 28.6 30.2 49.4 52.4 31.2 55.5 25.9 26.0 33.2 34.3 56.5 25.2 37.1 26.2 33.4 39.4 46.3 36.1 28.6 112.6 54.1 34.2 33.5 27.0 33.8 35.5 224.8 26.6 48.4 45.7 81.8 75.7 40.6 36.5 31.1 61.7 61.3 87.8 72.6 71.9 62.7 82.7 73.9 74.3 72.6 67.7 72.7 60.2 67.0 44.5 76.1 70.3 53.6 99.8 85.0 112.0 66.5 54.5 95.9 61.3 100.7 87.6 95.1 69.3 62.6 68.9 67.7 74.0 72.2 74.3 61.9 90.2 67.0 96.9 104.5 88.5 91.5 90.4 100.9 38.0 76.5 109.8 50.0 108.5 141.0 79.9 58.6 51.1 73.7 85.7 124.5 58.6 79.3 66.2 77.2 58.5 52.1 74.1 69.2 55.3 115.3 59.9 58.2 83.7 9.4 2.8 7.6 3.5 3.5 4.6 5.3 3.9 5.4 3.0 6.5 4.7 5.2 6.6 8.7 4.2 3.6 7.6 1.7 26.7 28.2 30.4 34.7 28.6 30.2 25.9 26.0 26.2 27.0 26.6 31.1 48.3 51.3 69.6 92.1 73.9 28.3 67.8 25.1 20.5 48.5 40.8 34.7 39.9 30.0 49.7 27.6 29.2 25.7 85.3 46.7 35.2 20.2 211.2 58.9 66.9 35.2 40.9 30.9 86.7 24.9 17.8 35.0 32.6 76.2 38.0 37.1 28.5 39.6 20.7 60.6 93.4 39.2 20.3 43.2 28.3 309.7 27.4 45.2 24.9 95.5 39.4 48.4 28.8 107.1 126.4 34.5 39.3 27.4 58.1 59.8 43.8 43.2 38.7 41.3 52.6 71.8 41.5 116.4 50.7 35.7 32.7 39.5 61.2 40.1 34.0 90.1 CCDC195 ENSG00000283428 "Coiled-coil domain containing 195" A0A1B0GUA6 2 224703764-224716365 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Daudi: 2.3;RPMI-8226: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DOCK10 "KIAA0694, ZIZ3" ENSG00000135905 "Dedicator of cytokinesis 10" Q96BY6 2 224765090-225042468 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.1;lymphoid tissue: 32.1" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1806.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 45.5;GAMG: 73.4;HDLM-2: 52.7;TIME: 48.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058106 Enhanced Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "HPA058106: AB_2683606" "unprognostic (6.95e-2)" "unprognostic (1.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-3)" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (3.44e-2)" "unprognostic (3.80e-1)" "unprognostic (3.22e-3)" "unprognostic (3.39e-1)" "unprognostic (1.24e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (2.54e-1)" "unprognostic (7.72e-2)" 4.5 8.2 22.6 18.8 49.2 10.2 3.8 33.7 33.4 8.7 9.7 6.3 4.1 3.2 1.1 3.2 2.4 6.3 1.6 28.7 35.1 3.2 5.5 7.6 27.8 45.5 38.4 17.7 1.7 2.0 1.0 2.3 48.9 1.6 6.5 5.7 2.5 1.7 1.2 5.0 12.5 4.3 32.0 29.8 6.7 2.2 37.9 32.1 2.7 0.8 19.9 6.4 4.4 83.1 0.0 21.4 6.7 0.0 8.5 17.9 0.0 45.5 36.8 21.3 15.8 0.0 0.0 0.6 0.1 28.9 73.4 0.5 0.0 0.1 16.9 52.7 0.0 0.6 4.5 0.0 0.3 4.4 2.1 4.3 0.4 31.0 12.0 8.3 21.4 7.0 0.1 42.1 36.4 2.1 8.0 6.1 2.6 0.0 5.0 10.5 9.8 6.2 1.1 0.1 0.4 5.5 0.0 0.0 4.8 1.2 1.4 20.0 48.2 22.8 5.7 10.9 15.6 0.0 0.0 0.0 32.2 29.6 10.1 3.0 3.3 0.2 6.5 9.2 6.6 7.2 10.9 9.1 6.9 4.5 10.5 9.3 0.1 14.3 11.8 2.8 8.4 4.5 22.6 49.2 33.7 33.4 28.7 35.1 45.5 38.4 48.9 32.0 37.9 83.1 3.7 3.2 9.1 4.2 47.1 4.7 0.6 0.3 8.0 7.9 0.8 4.3 1.2 0.0 2.5 5.5 0.0 0.3 39.5 0.8 1.9 0.1 3.2 0.2 2.3 3.2 2.4 5.5 8.0 0.0 0.2 4.9 5.1 0.5 36.7 64.0 2.5 1.4 30.6 97.6 244.2 3.8 0.0 54.2 39.7 2.8 0.6 51.0 8.8 201.4 38.3 1.2 38.1 400.6 1806.0 0.2 0.3 0.0 43.5 0.5 0.2 0.3 2.6 1.8 13.1 2.5 18.9 0.3 1.1 2.1 4.1 0.8 75.1 31.4 2.5 0.7 NYAP2 KIAA1486 ENSG00000144460 "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2" Q9P242 2 225399710-225654018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 8.7" "Group enriched" "Detected in some" 8 "Excitatory neurons: 136.8;Inhibitory neurons: 238.3" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 8.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045531, HPA056945" Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria Cytosol "HPA045531: AB_10960749, HPA056945: " "unprognostic (2.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.24e-1)" "unprognostic (2.63e-1)" "unprognostic (2.35e-1)" "unprognostic (6.13e-3)" "unprognostic (3.33e-1)" "unprognostic (2.08e-1)" "unprognostic (1.32e-8)" "unprognostic (9.83e-2)" "unprognostic (2.92e-1)" "unprognostic (6.46e-2)" "unprognostic (1.27e-1)" 0.0 0.0 0.8 0.0 1.6 0.0 0.0 0.7 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 1.9 0.0 0.0 0.2 0.0 0.1 8.7 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.6 0.7 2.7 1.7 1.9 0.1 8.7 2.0 2.9 2.4 0.0 0.1 0.0 2.3 4.9 0.1 1.3 1.7 0.0 0.0 21.8 0.2 0.0 0.5 0.0 0.6 0.0 2.1 0.2 0.2 0.1 0.0 0.3 0.6 0.2 0.1 0.4 0.0 0.0 136.8 1.2 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 238.3 0.0 0.0 0.8 1.8 0.8 0.0 0.6 0.0 1.0 0.2 0.5 0.0 1.5 2.5 1.2 0.0 0.0 0.1 1.1 0.0 0.1 0.0 1.5 0.0 3.6 0.5 0.2 0.1 0.0 1.0 0.1 0.5 0.0 0.0 0.8 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.4;Theca cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: AB_2732524" "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.6 9.7 1.7 2.9 1.6 0.5 11.7 5.2 3.1 14.7 1.8 10.3 3.9 17.4 1.9 3.6 15.0 5.6 5.0 1.6 1.0 3.4 10.5 5.0 1.7 1.8 1.6 20.9 3.5 3.3 1.5 9.5 1.2 7.8 2.7 1.5 3.0 7.0 28.0 5.2 5.1 10.3 2.0 2.0 5.3 0.8 1.6 8.1 20.0 2.9 1.3 11.6 6.6 1.5 5.7 26.0 18.6 0.7 25.0 14.8 0.0 15.6 12.2 20.4 13.0 15.0 14.4 2.3 2.5 10.6 14.0 10.0 1.2 15.0 11.5 5.9 1.0 0.1 1.7 7.1 12.5 0.5 0.1 20.7 8.1 16.1 14.5 12.3 0.0 2.3 3.0 22.7 14.0 22.6 4.9 6.6 7.5 3.6 14.3 1.1 24.1 0.1 9.3 18.9 3.2 0.5 5.0 3.6 8.4 14.9 13.7 0.3 1.3 26.8 24.2 20.9 15.1 10.6 4.6 3.4 26.5 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.2 3.1 1.6 1.0 1.8 1.6 1.2 2.0 1.6 1.5 1.7 19.2 4.6 5.9 2.7 35.4 31.9 29.7 19.4 19.3 36.9 28.1 13.4 14.3 12.8 0.0 0.0 6.4 0.0 13.2 17.6 15.4 1.6 22.1 28.4 2.1 2.4 0.0 17.3 11.4 0.6 28.3 2.0 24.3 0.0 75.4 1.8 57.4 1.7 20.2 31.3 6.5 24.4 1.3 4.6 1.8 22.7 3.6 16.0 15.0 0.8 8.4 0.0 26.7 1.7 11.1 8.2 14.7 9.5 14.5 23.4 3.0 8.1 1.7 13.1 9.5 22.8 1.0 1.2 4.2 23.7 18.3 1.2 110.3 7.7 22.8 RHBDD1 DKFZp547E052 ENSG00000144468 "Rhomboid domain containing 1" Q8TEB9 2 226835581-226999215 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Differentiation, Spermatogenesis" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 66.9;Microglial cells: 57.1;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 109.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 73.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013972, HPA057125" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" "HPA013972: AB_2178629, HPA057125: AB_2683343" "unprognostic (1.42e-1)" "unprognostic (5.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.23e-2)" "unprognostic (2.57e-1)" "unprognostic (2.91e-1)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.18e-1)" "unprognostic (9.40e-2)" "unprognostic (4.74e-3)" "unprognostic (4.97e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (9.77e-2)" "unprognostic (3.04e-2)" 10.3 8.9 11.2 13.6 20.9 11.9 11.5 12.2 13.6 11.6 1.8 11.5 10.3 13.6 12.5 11.5 12.9 10.9 10.3 8.8 15.2 12.0 15.1 9.9 16.1 15.6 15.0 13.6 13.9 16.5 4.4 9.9 17.1 13.1 11.2 7.4 9.6 13.3 8.9 8.8 11.8 14.3 15.7 14.2 11.4 17.4 16.8 37.5 15.6 8.6 16.9 11.5 7.0 22.8 10.7 9.3 9.9 15.1 28.6 28.8 0.0 24.1 20.9 12.6 14.6 8.3 18.7 10.1 19.8 25.2 18.0 11.9 0.1 26.8 23.9 25.1 9.9 15.3 5.9 6.7 31.5 15.2 8.0 25.6 38.2 23.8 51.4 14.3 9.8 26.7 41.7 25.6 13.4 18.9 27.8 8.5 0.0 12.2 10.3 12.0 0.1 14.9 10.3 13.3 9.7 7.3 13.6 5.1 18.8 17.6 14.1 18.9 13.1 5.6 12.2 22.0 7.5 28.8 14.9 73.9 17.8 19.6 16.2 10.4 13.7 12.8 7.3 20.0 11.8 22.1 11.0 8.9 17.2 24.5 12.6 10.6 3.3 11.8 13.8 21.1 16.2 10.8 11.2 20.9 12.2 13.6 8.8 15.2 15.6 15.0 17.1 15.7 16.8 22.8 6.6 12.8 6.4 66.9 28.4 5.2 8.5 7.2 8.0 8.0 7.6 4.2 16.6 4.3 8.1 11.0 16.7 7.6 9.3 6.6 3.9 7.0 16.7 8.3 8.6 6.8 1.8 15.2 28.4 9.3 4.1 9.3 8.2 7.8 8.2 22.7 3.3 14.0 5.2 11.8 41.5 6.1 6.1 8.2 4.4 24.4 5.6 7.6 12.4 57.1 6.2 6.3 9.2 55.8 109.0 8.3 1.9 6.8 48.8 13.2 6.8 3.4 7.1 6.3 0.0 5.6 6.6 15.2 9.5 7.3 5.5 5.6 8.6 25.7 5.7 8.9 COL4A4 CA44 ENSG00000081052 "Collagen type IV alpha 4 chain" P53420 2 227002714-227164453 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Collecting duct cells: 46.0;Cone photoreceptor cells: 56.3;Granulosa cells: 62.6;Muller glia cells: 78.6;Oligodendrocyte precursor cells: 55.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "memory B-cell: 4.1" "Lineage enriched" "Detected in single" 5 "B-cells: 4.1" "Cell line enhanced" "Detected in some" "HeLa: 34.3;hTERT-RPE1: 27.2;Karpas-707: 8.9;RPTEC TERT1: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "unprognostic (7.31e-2)" "unprognostic (7.56e-2)" "unprognostic (6.65e-2)" "unprognostic (4.88e-5)" "unprognostic (1.12e-1)" "unprognostic (2.92e-2)" "unprognostic (8.50e-3)" "unprognostic (5.14e-2)" "unprognostic (1.44e-1)" "unprognostic (1.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.91e-2)" "prognostic favorable (2.30e-13)" "unprognostic (1.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.15e-2)" 1.0 6.9 1.3 2.1 1.1 0.1 0.7 0.9 0.9 0.5 14.2 0.9 0.9 2.0 7.2 1.1 2.1 4.4 9.2 1.0 1.3 14.0 1.6 8.3 2.8 3.1 2.2 2.0 5.5 0.6 10.2 0.3 2.6 4.5 0.8 8.4 0.7 8.3 6.9 0.3 2.4 1.6 1.5 1.9 1.2 1.3 4.4 0.9 9.9 5.7 4.5 2.9 0.9 1.3 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.3 0.2 0.1 0.6 0.0 0.7 0.0 1.7 0.0 0.7 0.1 3.1 1.1 0.2 0.0 3.4 0.0 34.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 27.2 0.0 1.1 0.0 8.9 0.0 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 2.9 14.5 5.6 0.8 0.0 2.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 2.7 0.0 0.3 6.7 5.3 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.3 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.3 1.1 0.9 0.9 1.0 1.3 3.1 2.2 2.6 1.5 4.4 1.3 2.0 73.7 24.1 3.6 11.1 0.5 0.4 0.2 0.0 29.1 0.5 1.3 3.5 8.6 6.2 46.0 56.3 0.0 1.4 0.1 1.9 0.3 0.8 0.3 1.8 5.2 1.2 0.0 2.5 3.8 0.0 8.1 1.5 0.9 0.0 62.6 2.5 0.7 0.1 0.0 10.4 0.1 2.0 0.3 1.5 4.3 25.1 0.8 0.0 12.2 0.0 78.6 0.0 55.3 3.4 4.1 0.1 27.1 14.9 0.2 0.0 3.6 0.0 8.5 0.0 16.8 8.6 0.1 0.6 0.2 0.0 0.0 1.4 0.9 0.3 0.1 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 985.9;Late spermatids: 1746.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010968, HPA074625" Enhanced Supported Mitochondria No No 62000 "Cluster 2: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA010968: AB_1845714, HPA074625: AB_2686704" "unprognostic (2.75e-2)" "unprognostic (1.35e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-2)" "unprognostic (1.73e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.20e-4)" "unprognostic (3.07e-2)" "unprognostic (1.32e-1)" "unprognostic (6.07e-2)" "unprognostic (3.00e-2)" "unprognostic (6.24e-3)" "unprognostic (5.50e-2)" "unprognostic (1.00e-1)" "unprognostic (2.70e-2)" "unprognostic (1.51e-1)" "unprognostic (3.22e-1)" 52.3 58.0 61.2 29.3 66.6 48.1 46.9 67.4 71.8 49.0 63.5 60.9 41.0 46.6 37.9 48.4 49.0 31.0 66.2 60.0 67.3 68.8 44.2 38.9 39.4 66.4 61.7 51.6 57.2 60.0 42.7 33.4 66.1 42.5 40.9 80.4 43.8 47.9 100.4 44.8 40.5 42.3 67.3 38.7 49.0 199.2 63.5 51.5 37.1 86.5 44.5 50.1 45.9 74.5 71.1 60.6 72.4 100.5 92.7 88.6 95.3 69.1 93.7 82.6 88.7 66.4 49.8 40.3 80.1 76.9 87.5 57.8 121.0 88.5 112.6 86.4 97.3 85.8 144.5 165.0 122.4 84.2 73.6 79.6 113.9 79.0 84.3 109.6 72.7 91.6 76.7 117.8 75.3 72.5 88.9 127.3 98.6 76.7 62.5 79.0 91.8 78.7 124.2 66.5 76.3 70.8 153.3 68.7 106.7 59.4 44.8 82.0 49.7 80.6 67.0 119.2 78.3 95.2 69.6 81.9 106.1 73.6 111.7 118.5 66.8 133.6 65.2 74.0 69.9 84.0 67.5 63.9 72.0 77.9 70.4 60.2 65.1 67.7 70.0 71.9 97.5 76.3 61.2 66.6 67.4 71.8 60.0 67.3 66.4 61.7 66.1 67.3 63.5 74.5 40.4 32.1 46.7 53.8 74.8 48.3 62.1 70.3 90.5 33.1 54.9 64.1 79.3 44.3 57.0 60.7 31.3 95.3 49.8 46.2 127.2 95.2 985.9 36.7 40.3 45.6 32.3 73.6 95.8 94.8 89.8 67.6 42.8 52.0 22.1 66.4 43.5 56.1 78.4 40.4 97.7 60.3 61.1 61.5 56.4 1746.9 88.0 63.0 81.8 47.8 64.0 204.4 74.2 135.2 151.3 91.7 63.8 85.7 127.7 66.5 69.5 135.7 32.3 65.5 59.2 69.1 62.1 392.3 96.9 87.6 47.3 91.9 57.2 63.7 73.0 71.6 TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 266.6" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 703.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.6;RPMI-8226: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" 0.1 0.1 0.2 0.3 0.2 0.2 0.0 1.2 0.4 0.0 0.4 3.1 266.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.3 0.0 0.0 0.0 0.3 144.5 1.6 0.0 0.1 0.5 3.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 1.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 48.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.4 0.0 0.0 0.0 77.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 157.9 0.7 0.0 0.0 703.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 18.8 0.0 SCYGR1 KRTAP28-1 ENSG00000284629 "Small cysteine and glycine repeat containing 1" A0A286YEY9 2 227387683-227387949 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.4 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.4 0.5 0.4 0.4 0.7 0.6 0.8 0.5 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA008741: AB_1850752" "unprognostic (5.76e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (8.73e-3)" "unprognostic (6.31e-3)" "prognostic favorable (6.10e-4)" "unprognostic (9.30e-3)" "prognostic unfavorable (7.31e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (2.03e-2)" "unprognostic (5.78e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (1.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-3)" 69.4 39.4 30.4 48.4 31.6 155.5 51.1 29.3 36.0 25.3 23.8 32.2 43.4 25.7 20.1 47.2 27.3 38.9 36.2 32.4 27.0 36.9 36.2 54.6 47.1 34.6 29.0 26.1 35.0 41.6 17.9 75.8 33.4 21.0 33.0 47.7 27.9 23.4 33.9 36.3 36.2 39.3 33.6 46.5 33.2 92.8 34.5 48.6 34.3 38.6 53.3 65.7 32.2 47.3 60.5 97.9 50.8 49.6 84.8 62.1 191.6 78.4 74.6 92.0 81.2 77.4 67.6 42.7 58.3 86.8 123.8 62.2 87.9 101.7 118.6 72.3 48.9 94.1 80.8 144.3 90.9 64.7 57.0 38.3 106.4 116.7 109.5 70.3 93.7 43.3 100.3 112.0 111.8 85.8 77.8 58.0 79.3 80.4 50.4 70.8 83.6 30.3 91.7 81.5 47.0 36.7 64.1 82.5 74.7 87.6 35.3 72.4 92.7 78.8 63.0 114.7 70.0 64.5 46.9 59.6 85.6 54.4 92.5 4.1 5.3 1.9 1.6 4.3 3.2 2.0 1.8 1.5 3.3 3.5 1.5 2.8 5.6 1.1 4.2 2.3 2.3 1.6 30.4 31.6 29.3 36.0 32.4 27.0 34.6 29.0 33.4 33.6 34.5 47.3 36.6 25.6 23.6 45.7 27.2 33.1 37.5 18.0 18.2 37.7 29.3 22.1 23.3 17.2 19.6 22.0 25.0 31.0 26.5 28.2 15.6 17.5 162.3 32.7 34.9 29.1 34.1 13.3 114.2 21.5 17.5 26.8 39.8 65.8 12.7 30.4 23.6 22.9 24.1 43.7 74.9 20.4 12.2 92.8 33.6 333.2 15.5 67.3 19.6 119.9 48.4 43.3 19.6 109.6 116.0 32.6 18.0 11.7 22.7 39.4 31.3 27.4 15.5 35.4 19.7 83.8 21.7 72.6 18.4 25.0 32.1 39.7 24.0 20.6 22.2 57.9 SCYGR2 KRTAP28-2 ENSG00000284643 "Small cysteine and glycine repeat containing 2" A0A286YFB4 2 227598893-227599255 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCYGR3 KRTAP28-3 ENSG00000284704 "Small cysteine and glycine repeat containing 3" A0A286YF60 2 227614538-227614840 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCYGR4 KRTAP28-4 ENSG00000284631 "Small cysteine and glycine repeat containing 4" A0A286YEV6 2 227616998-227618655 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.0;placenta: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "U-2197: 10.7" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" 0.1 0.0 1.1 0.6 0.4 1.0 0.0 0.4 1.0 0.0 0.0 0.0 0.2 0.2 2.0 0.1 0.0 0.1 0.1 0.5 0.3 0.1 0.8 0.1 0.2 0.6 0.4 0.1 0.4 0.0 5.0 0.7 0.1 0.0 1.4 0.1 0.1 0.2 0.6 0.0 0.1 0.2 0.2 0.0 0.4 0.6 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.4 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.5 0.1 0.1 10.7 0.2 0.1 0.0 0.3 0.1 0.0 0.2 0.9 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.2 0.0 0.0 1.1 0.4 0.4 1.0 0.5 0.3 0.6 0.4 0.7 0.2 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SCYGR5 KRTAP28-5 ENSG00000284667 "Small cysteine and glycine repeat containing 5" A0A286YF46 2 227666804-227667061 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SCYGR6 KRTAP28-6 ENSG00000284725 "Small cysteine and glycine repeat containing 6" A0A286YF77 2 227724440-227724757 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCYGR7 KRTAP28-7 ENSG00000284718 "Small cysteine and glycine repeat containing 7" A0A286YF01 2 227728335-227728625 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SCYGR8 KRTAP28-8 ENSG00000284635 "Small cysteine and glycine repeat containing 8" A0A286YFG1 2 227745845-227746681 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCL20 "CKb4, exodus-1, LARC, MIP-3a, SCYA20, ST38" ENSG00000115009 "C-C motif chemokine ligand 20" P78556 2 227805739-227817564 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" "Antibiotic, Antimicrobial, Cytokine" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 162.6;lymphoid tissue: 165.5;urinary bladder: 192.8" "Group enriched" "Detected in many" 7 "Basal respiratory cells: 25281.7;Club cells: 7424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.7" "Lineage enriched" "Detected in single" 9 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "GAMG: 63.1;Hep G2: 35.7;NB-4: 25.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 28000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (2.40e-1)" "unprognostic (1.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (7.06e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (9.29e-4)" "unprognostic (1.53e-3)" "unprognostic (1.37e-1)" "unprognostic (5.21e-1)" "prognostic unfavorable (2.73e-4)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.19e-8)" "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (1.63e-1)" "unprognostic (1.82e-1)" 10.1 0.3 1.9 31.8 2.2 7.3 0.7 3.6 2.7 23.9 0.2 19.7 16.4 13.7 0.8 12.2 2.7 162.6 2.0 1.9 1.5 9.1 20.1 35.4 6.2 1.9 1.4 0.9 1.8 0.2 0.2 1.3 2.1 2.8 27.0 1.8 5.0 0.5 0.6 8.2 26.6 4.7 1.5 0.4 11.2 2.1 2.6 2.6 0.6 0.2 165.5 192.8 4.6 3.5 0.5 1.4 0.7 0.9 3.2 6.0 0.9 0.4 2.1 0.2 0.8 3.9 0.6 1.3 4.4 0.0 63.1 0.7 0.2 8.7 1.4 0.9 1.5 0.2 3.3 35.7 2.4 4.7 0.4 10.1 1.8 2.0 2.4 1.0 0.0 1.2 0.3 5.1 0.5 0.4 0.3 25.7 1.8 5.3 0.8 0.7 8.6 1.0 0.3 15.4 0.6 0.5 0.3 1.5 0.9 0.8 1.4 5.7 2.3 3.3 4.1 7.2 0.7 1.0 3.2 2.1 5.0 3.5 6.6 0.0 0.1 0.0 0.0 0.0 2.7 0.1 1.1 0.6 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 1.9 2.2 3.6 2.7 1.9 1.5 1.9 1.4 2.1 1.5 2.6 3.5 2.8 48.1 108.5 0.0 5.6 118.8 554.4 25281.7 21.6 0.6 1.9 1.9 0.9 65.8 7424.9 18.4 0.0 0.5 2.4 135.0 0.0 310.9 16.0 51.9 44.4 5.1 57.9 0.0 0.0 2.9 0.5 9.2 50.4 517.8 5.7 0.0 0.0 1.7 29.1 1.7 0.0 161.0 2203.3 4.0 149.2 1.2 0.0 333.0 1.8 0.0 9.4 0.0 0.0 0.0 0.0 24.1 459.7 0.0 4.5 259.5 331.0 9.3 1477.8 0.2 0.0 0.7 115.1 1.2 1.2 224.9 64.8 0.8 68.2 0.0 121.9 1062.1 DAW1 "FLJ25955, ODA16, WDR69" ENSG00000123977 "Dynein assembly factor with WD repeats 1" Q8N136 2 227871054-227924344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 25.7;fallopian tube: 32.6;testis: 51.3" "Group enriched" "Detected in some" 13 "Early spermatids: 106.7;Late spermatids: 215.3;Respiratory ciliated cells: 113.9;Spermatocytes: 177.1" "Cancer enhanced" "Detected in some" "lung cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HUVEC TERT2: 21.8;U-2197: 40.7" "Low region specificity" "Detected in many" HPA046118 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Plasma membrane" "HPA046118: AB_10961428" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (4.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.63e-3)" "unprognostic (2.90e-2)" "unprognostic (9.92e-3)" "unprognostic (1.54e-5)" "unprognostic (1.52e-1)" "unprognostic (6.83e-3)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" 0.6 0.0 4.3 0.1 5.3 0.3 0.4 2.9 4.7 0.7 25.7 0.2 0.0 0.1 0.3 0.5 32.6 0.3 0.5 4.5 4.5 0.2 0.4 3.0 0.2 7.3 8.8 0.1 0.0 0.2 0.2 0.8 5.5 0.0 0.0 0.7 0.1 0.0 3.6 0.2 0.0 0.1 6.8 0.2 0.1 51.3 5.4 0.4 0.1 0.0 0.2 0.1 0.0 5.4 0.8 0.0 0.1 0.0 0.3 1.2 0.6 0.8 0.4 0.9 0.6 5.4 0.5 0.2 0.0 0.2 8.8 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.1 1.7 0.0 1.0 0.7 5.8 21.8 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.1 0.3 0.1 0.2 0.4 0.1 0.8 0.0 0.0 0.2 0.0 0.5 2.2 0.2 2.0 40.7 0.0 0.0 0.1 0.3 3.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.3 2.9 4.7 4.5 4.5 7.3 8.8 5.5 6.8 5.4 5.4 0.0 0.0 1.1 0.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.7 0.0 11.5 0.0 4.2 0.2 0.0 0.0 0.0 0.2 106.7 11.2 0.0 0.2 0.0 0.0 6.2 0.0 2.8 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 8.2 0.0 0.0 215.3 3.4 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 3.0 0.2 2.6 0.0 0.1 0.0 0.1 113.9 0.3 0.0 0.7 2.1 177.1 4.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 SPHKAP SKIP ENSG00000153820 "SPHK1 interactor, AKAP domain containing" Q2M3C7 2 227979955-228181687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 78.3;heart muscle: 29.1" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 82.2;Excitatory neurons: 67.7;Granulosa cells: 33.6;Inhibitory neurons: 128.6" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 78.3;cerebral cortex: 49.3;hippocampal formation: 41.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 17 "BJ hTERT+: 45.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042499, HPA048168" Enhanced NA NA "Cluster 6: Brain - Smell perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042499: AB_2678027, HPA048168: AB_2680296" "unprognostic (4.91e-3)" "unprognostic (6.46e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-2)" "unprognostic (2.95e-2)" "unprognostic (2.09e-1)" "unprognostic (1.01e-3)" 0.0 0.1 10.6 0.0 8.8 0.0 0.8 78.3 49.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 41.1 4.2 0.0 0.0 0.1 0.0 6.8 13.3 2.1 0.0 0.0 0.0 0.0 7.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.4 0.0 0.2 11.2 0.3 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 45.9 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 8.8 78.3 49.3 41.1 4.2 6.8 13.3 7.1 4.2 11.2 3.3 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.2 2.6 3.0 82.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.0 67.7 0.0 0.0 2.1 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 128.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 9.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PID1 "FLJ20701, NYGGF4" ENSG00000153823 "Phosphotyrosine interaction domain containing 1" Q7Z2X4 2 228850526-229271287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.0;Inhibitory neurons: 142.2;Langerhans cells: 210.4;Microglial cells: 179.9;Oligodendrocyte precursor cells: 543.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 71.1;intermediate monocyte: 79.4;myeloid DC: 83.6" "Group enriched" "Detected in many" 53 "dendritic cells: 83.6;monocytes: 79.4" "Cell line enhanced" "Detected in many" "ASC diff: 54.5;hTEC/SVTERT24-B: 86.1;LHCN-M2: 57.3;REH: 62.3;RH-30: 90.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036103 Approved Approved "Endoplasmic reticulum" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA036103: AB_10602144" "unprognostic (8.46e-2)" "unprognostic (2.96e-1)" "unprognostic (3.55e-2)" "unprognostic (5.52e-2)" "unprognostic (9.40e-3)" "unprognostic (2.66e-2)" "unprognostic (1.21e-2)" "unprognostic (6.36e-2)" "unprognostic (1.54e-2)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.46e-1)" "unprognostic (4.91e-3)" "unprognostic (9.98e-3)" "unprognostic (1.11e-1)" "unprognostic (5.34e-2)" "unprognostic (9.61e-6)" 31.2 29.5 18.8 13.9 20.8 2.9 25.8 9.0 21.2 30.2 9.0 37.6 5.5 22.9 8.9 12.0 33.9 12.7 17.0 20.6 15.5 5.6 62.2 24.4 4.4 14.8 30.5 31.0 13.8 1.5 8.8 26.1 13.6 19.2 21.5 3.8 10.2 14.8 13.1 20.0 25.1 16.7 11.8 20.3 25.5 5.5 21.4 3.4 16.6 20.8 3.6 30.9 27.0 13.8 0.0 1.9 0.0 0.0 54.5 10.5 0.1 9.2 34.7 5.8 7.1 0.7 0.0 0.0 0.2 13.0 18.0 1.7 0.0 1.7 7.8 0.0 0.0 0.0 4.0 0.1 22.3 0.0 0.1 19.8 15.5 86.1 14.0 16.1 0.0 0.0 0.0 0.1 57.3 0.1 0.1 0.0 0.9 7.6 5.2 62.3 90.7 0.1 1.1 0.0 1.8 2.3 19.4 1.8 0.1 0.7 0.2 0.0 0.0 22.3 8.3 21.1 8.8 0.1 0.0 0.0 29.3 0.1 3.7 0.0 71.1 0.0 0.0 79.4 0.4 0.2 0.0 0.2 83.6 0.0 0.0 0.0 1.5 0.0 16.7 0.4 0.3 28.4 18.8 20.8 9.0 21.2 20.6 15.5 14.8 30.5 13.6 11.8 21.4 13.8 4.0 6.4 70.9 53.8 1.6 15.6 6.1 13.5 6.8 5.7 0.9 1.7 2.6 8.6 11.1 0.0 0.0 1.9 0.2 75.7 0.0 2.5 0.1 1.4 37.8 4.1 4.9 0.4 121.0 4.0 31.5 107.3 1.1 4.4 6.3 7.8 4.2 135.0 3.3 0.0 142.2 11.9 4.1 42.5 210.4 1.9 88.0 50.1 21.4 179.9 35.2 14.0 1.0 543.4 3.5 1.6 24.2 75.2 0.5 21.9 39.5 0.3 2.5 1.3 0.0 4.8 8.7 0.4 2.1 1.4 14.5 4.8 2.4 41.0 36.0 1.4 DNER "bet, UNQ26" ENSG00000187957 "Delta/notch like EGF repeat containing" Q8NFT8 2 229357629-229714555 "Cancer-related genes, Predicted membrane proteins" "Notch signaling pathway" "Activator, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 73.0;brain: 147.5;choroid plexus: 143.8" "Group enriched" "Detected in many" 4 "Bipolar cells: 123.3;Inhibitory neurons: 333.0;Oligodendrocyte precursor cells: 435.8;Oligodendrocytes: 247.7" "Cancer enriched" "Detected in many" 32 "glioma: 73.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "GAMG: 368.0;hTERT-HME1: 149.7;hTERT-RPE1: 409.5;U-138 MG: 252.2;U-87 MG: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017320 Enhanced NA NA 7900000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017320: AB_1847808" "unprognostic (4.39e-2)" "unprognostic (1.83e-1)" "unprognostic (3.25e-1)" "unprognostic (1.00e-3)" "unprognostic (8.73e-2)" "unprognostic (6.23e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.23e-3)" "unprognostic (2.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.42e-4)" "unprognostic (2.59e-2)" "unprognostic (7.32e-2)" "unprognostic (5.63e-2)" "unprognostic (5.13e-3)" 2.0 73.0 88.3 1.3 121.0 0.0 2.3 139.7 82.9 2.0 143.8 5.2 0.4 2.8 5.7 0.3 4.1 0.2 11.8 72.3 130.9 11.2 0.1 1.0 0.3 121.3 121.0 0.6 0.9 8.9 30.3 0.4 117.8 1.9 1.1 60.5 43.4 0.4 0.8 10.3 1.6 1.2 124.7 0.1 10.7 1.0 147.5 0.5 0.1 0.5 1.2 0.8 1.1 137.2 0.4 1.9 3.9 0.3 0.6 0.5 0.0 0.2 1.4 8.6 2.6 0.0 1.1 0.0 0.4 0.1 368.0 0.1 0.3 1.2 4.3 0.0 0.1 0.0 12.4 0.0 1.4 0.0 0.1 2.6 9.3 6.5 149.7 409.5 0.0 0.0 0.0 0.3 2.3 0.1 0.0 0.0 2.5 0.2 14.0 0.1 1.6 0.0 14.6 0.0 30.3 2.5 0.8 0.1 0.8 0.4 0.1 0.0 0.0 252.2 0.0 8.5 39.7 0.0 0.0 0.0 149.6 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 88.3 121.0 139.7 82.9 72.3 130.9 121.3 121.0 117.8 124.7 147.5 137.2 0.1 0.0 0.0 68.9 0.0 0.4 5.9 1.9 1.8 123.3 1.6 0.6 12.2 0.0 1.4 3.7 14.6 0.0 0.0 0.0 1.9 0.2 7.3 4.1 1.5 0.6 28.7 0.0 24.1 1.3 0.2 4.3 0.0 6.7 0.0 1.6 0.0 0.0 0.1 11.8 333.0 0.0 6.1 0.0 0.8 1.9 5.9 0.9 19.6 8.4 0.1 52.0 0.0 435.8 247.7 0.3 0.0 6.0 0.0 4.5 0.0 1.2 34.1 55.0 0.0 0.1 0.8 1.2 1.1 0.5 0.0 0.1 0.2 0.6 0.1 0.5 TRIP12 "KIAA0045, TRIPC, ULF" ENSG00000153827 "Thyroid hormone receptor interactor 12" Q14669 2 229763837-229923239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Autism spectrum disorder, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036835, HPA045893" Enhanced Approved "Nuclear speckles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nuclear speckles" "HPA036835: AB_2675340, HPA045893: AB_2679486" "unprognostic (1.22e-1)" "unprognostic (4.87e-2)" "unprognostic (2.61e-1)" "unprognostic (3.33e-2)" "unprognostic (6.81e-2)" "unprognostic (1.88e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.37e-3)" "unprognostic (3.49e-3)" "unprognostic (4.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.62e-1)" "unprognostic (6.83e-2)" "unprognostic (8.80e-2)" "unprognostic (2.01e-2)" 48.2 32.3 20.2 47.1 26.7 53.9 33.6 20.2 31.4 34.8 15.7 40.8 25.6 30.8 33.4 47.6 28.1 33.9 41.5 16.0 25.4 41.3 42.8 33.3 48.2 20.7 20.8 32.7 29.3 45.0 24.8 44.6 22.1 39.9 33.9 34.8 30.2 33.0 81.7 29.3 27.6 38.2 17.9 41.1 39.1 127.7 21.5 60.3 44.5 59.0 56.3 46.3 26.5 30.0 97.1 100.7 96.2 79.0 94.9 106.2 88.3 144.5 103.0 106.9 118.7 80.5 75.3 37.8 96.2 135.6 129.5 76.3 140.5 105.9 159.3 132.4 52.9 264.1 84.4 78.3 76.4 195.8 163.2 88.1 80.3 174.9 108.5 74.9 145.1 88.2 188.2 38.2 122.5 72.5 105.3 68.5 77.0 50.3 47.7 94.8 189.8 33.6 75.7 156.4 94.4 67.5 1.6 51.9 97.7 85.1 48.2 118.3 188.8 133.9 94.7 84.9 115.5 66.4 79.3 119.0 103.8 77.0 116.6 34.0 14.2 23.6 12.9 16.2 13.1 9.6 12.0 12.7 13.4 8.9 9.5 9.7 36.0 13.9 18.7 12.6 19.5 9.8 20.2 26.7 20.2 31.4 16.0 25.4 20.7 20.8 22.1 17.9 21.5 30.0 78.3 89.8 51.2 85.8 43.4 31.0 32.8 36.3 25.6 31.2 41.2 29.8 91.0 34.3 52.8 31.3 52.1 27.0 60.8 57.3 15.6 37.5 119.5 63.5 65.2 59.3 18.6 40.2 147.6 45.1 25.1 43.7 56.6 73.5 39.2 53.1 50.0 54.3 35.1 42.1 130.3 32.5 30.5 89.6 32.2 102.1 34.8 70.8 26.6 122.7 63.9 25.8 56.7 127.2 251.3 57.8 35.0 45.5 52.1 44.7 25.7 34.5 73.1 32.1 19.7 57.5 45.0 137.2 59.3 43.1 36.2 42.4 47.0 60.2 31.9 54.5 FBXO36 "Fbx36, FLJ37592" ENSG00000153832 "F-box protein 36" Q8NEA4 2 229922302-230013119 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Early spermatids: 61.7;Endometrial ciliated cells: 40.8;Respiratory ciliated cells: 53.0;Spermatocytes: 55.8" "Cancer enhanced" "Detected in all" "testis cancer: 9.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053865 Approved Nucleoplasm,Nucleoli NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "HPA053865: AB_2682282" "unprognostic (4.39e-3)" "unprognostic (6.51e-2)" "unprognostic (2.38e-2)" "prognostic favorable (2.28e-4)" "unprognostic (2.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.15e-2)" "unprognostic (2.38e-2)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.28e-2)" "unprognostic (8.04e-2)" "unprognostic (7.79e-3)" "unprognostic (3.72e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.68e-1)" 1.9 3.7 4.6 0.7 4.2 0.8 3.5 4.3 4.5 3.0 3.9 1.2 1.4 2.5 2.8 1.6 11.0 1.7 1.2 3.7 4.4 5.1 1.6 2.3 0.9 5.8 5.6 2.4 1.6 4.3 2.7 1.6 5.1 2.9 1.2 9.0 2.3 2.5 0.8 3.0 1.4 1.7 5.4 0.8 1.7 6.0 4.4 1.5 7.4 0.8 1.0 1.3 1.5 5.1 1.0 1.9 2.3 0.9 1.1 6.8 4.6 1.2 3.2 1.7 2.9 0.7 3.1 0.1 0.6 2.2 2.1 0.8 1.1 0.6 2.9 0.3 0.7 0.4 0.6 1.2 4.4 0.8 0.3 7.2 5.2 3.2 2.4 2.2 1.8 3.4 1.4 0.6 2.0 4.2 1.7 1.9 6.1 2.2 2.2 2.0 0.6 0.5 3.0 0.8 2.2 2.8 2.0 1.6 0.8 2.6 3.4 1.4 1.3 2.8 1.0 4.6 0.5 2.1 1.8 0.7 3.4 0.4 2.1 0.0 0.5 0.0 0.8 0.4 0.6 1.1 0.6 0.6 1.3 0.7 1.4 0.8 0.2 1.0 0.3 0.6 1.2 0.5 4.6 4.2 4.3 4.5 3.7 4.4 5.8 5.6 5.1 5.4 4.4 5.1 3.1 9.6 1.1 11.4 1.1 3.8 2.9 8.3 1.2 8.3 4.3 4.3 3.7 0.0 9.9 11.0 35.5 1.9 0.6 2.3 15.6 6.2 61.7 40.8 4.9 2.3 0.0 2.5 19.5 6.6 2.0 3.7 3.1 4.7 0.0 4.2 1.4 2.7 1.1 10.1 22.1 1.6 14.2 1.6 3.0 10.5 3.4 1.2 3.6 5.6 2.9 7.5 4.1 12.5 12.5 6.2 0.5 4.1 0.7 3.0 2.2 12.2 53.0 28.8 6.6 2.8 4.2 55.8 8.6 3.2 4.5 2.2 1.5 9.1 1.4 1.9 SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 18.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.0;Excitatory neurons: 18.5;Inhibitory neurons: 21.1;Microglial cells: 45.0;Oligodendrocyte precursor cells: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cell line enhanced" "Detected in many" "HL-60: 24.2;Karpas-707: 15.2;REH: 19.5;RPMI-8226: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "HPA040518: AB_10794877" "unprognostic (2.99e-1)" "unprognostic (1.74e-1)" "unprognostic (2.63e-1)" "unprognostic (1.74e-3)" "unprognostic (2.20e-3)" "unprognostic (2.01e-1)" "unprognostic (4.96e-2)" "unprognostic (1.95e-1)" "unprognostic (3.15e-1)" "unprognostic (5.70e-3)" "unprognostic (1.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.03e-3)" "unprognostic (3.51e-1)" "unprognostic (2.39e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" 4.6 3.9 7.9 1.7 7.2 5.6 3.2 8.9 7.7 5.0 2.4 3.7 1.0 3.9 2.3 4.0 3.1 2.8 2.4 7.1 7.2 2.3 2.0 1.9 1.3 5.2 6.1 7.3 0.8 7.0 1.4 1.2 4.7 4.5 4.0 2.5 18.6 3.6 1.0 11.0 1.3 3.8 3.8 5.9 1.4 1.2 9.4 2.2 1.5 2.0 1.5 2.0 2.7 4.7 2.9 1.6 1.3 0.0 0.0 0.3 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.3 0.1 0.0 0.5 5.1 1.4 0.1 0.0 9.7 0.2 3.1 0.0 0.3 24.2 0.0 0.5 3.6 0.0 0.0 3.9 0.2 4.7 0.0 15.2 0.3 0.0 2.4 2.7 1.0 0.3 2.7 19.5 0.0 17.3 5.6 2.6 6.3 2.3 4.9 0.0 0.1 0.1 7.7 1.9 0.0 0.0 1.3 3.3 2.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 11.3 0.4 0.0 0.3 0.3 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 7.9 7.2 8.9 7.7 7.1 7.2 5.2 6.1 4.7 3.8 9.4 4.7 17.0 0.0 0.0 2.3 1.5 2.5 0.5 1.9 3.4 3.3 1.2 0.8 3.9 0.0 3.5 0.0 2.1 0.0 0.1 1.8 0.0 0.8 0.0 0.5 2.6 10.8 3.6 0.0 18.5 0.6 0.0 2.3 0.0 0.3 0.0 0.2 4.2 2.1 0.1 3.3 21.1 0.3 4.1 0.3 0.6 0.0 1.2 0.1 1.8 45.0 0.0 1.9 0.0 13.6 1.8 0.8 1.0 3.0 8.4 0.9 0.0 0.3 1.6 1.6 0.0 0.5 1.4 0.2 0.2 6.8 4.7 0.3 1.4 8.4 1.3 0.3 SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 53.7" "Cell type enhanced" "Detected in many" "B-cells: 141.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 99.3" "Low region specificity" "Detected in all" HPA058554 Supported Nucleoplasm No No "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "HPA058554: AB_2683754" "unprognostic (9.72e-2)" "unprognostic (1.15e-2)" "unprognostic (5.02e-2)" "unprognostic (8.33e-4)" "unprognostic (2.93e-1)" "unprognostic (1.80e-1)" "unprognostic (6.65e-2)" "unprognostic (9.44e-2)" "unprognostic (9.68e-2)" "unprognostic (1.46e-2)" "unprognostic (4.11e-3)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.17e-5)" "unprognostic (2.38e-1)" "unprognostic (2.66e-2)" "unprognostic (2.99e-3)" "unprognostic (9.50e-3)" 14.0 7.3 8.4 38.5 10.3 29.8 11.8 9.4 10.8 11.6 11.5 12.6 11.9 10.5 7.9 9.2 9.6 18.0 8.1 8.1 10.3 11.9 14.8 21.0 53.7 15.3 10.9 16.5 7.9 9.7 5.3 17.5 11.6 9.6 14.0 2.0 17.0 7.6 5.7 7.8 17.6 13.4 12.1 49.8 12.9 3.1 10.9 35.7 7.4 8.4 50.1 18.9 9.3 12.3 8.3 4.4 2.7 4.7 14.2 23.6 8.3 14.8 30.8 70.3 99.3 0.2 12.7 34.5 13.8 15.8 67.0 5.1 9.0 23.0 25.7 30.5 6.0 14.9 6.2 8.9 14.5 22.1 17.1 32.7 11.8 20.8 27.4 13.2 25.3 23.6 5.3 12.1 20.6 4.9 33.0 43.5 8.6 4.2 5.1 20.1 25.4 12.8 56.2 11.1 0.5 5.7 5.7 12.7 32.7 0.9 9.6 18.5 18.8 12.9 7.9 3.2 7.5 12.9 4.6 16.2 14.4 20.6 10.7 92.2 49.7 124.4 55.2 85.8 47.8 142.8 53.5 50.5 44.1 135.8 54.1 58.7 268.6 56.9 143.4 84.4 70.7 48.5 8.4 10.3 9.4 10.8 8.1 10.3 15.3 10.9 11.6 12.1 10.9 12.3 77.8 44.8 23.8 17.3 141.7 9.9 5.2 25.7 16.5 0.4 21.6 19.3 3.7 7.2 19.6 11.0 0.0 3.8 84.0 17.0 13.7 19.9 5.2 17.2 21.3 28.6 6.7 9.7 1.1 28.5 12.7 22.8 9.2 20.1 38.0 21.2 26.4 6.2 26.9 0.0 2.1 11.4 73.2 47.4 25.8 4.2 11.8 62.3 19.6 42.2 56.7 9.7 59.8 19.6 18.2 26.0 11.6 10.1 35.7 3.5 10.7 14.4 21.0 4.9 6.6 8.6 16.2 4.8 2.3 9.8 10.1 4.7 68.8 23.5 6.1 3.0 SP140 "LYSP100-A, LYSP100-B" ENSG00000079263 "SP140 nuclear body protein" Q13342 2 230203110-230313215 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 15.6;lymphoid tissue: 55.8" "Cell type enhanced" "Detected in many" "B-cells: 149.9;dendritic cells: 37.4;NK-cells: 50.4;Plasma cells: 77.2;T-cells: 62.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 97.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 31.1;HDLM-2: 52.4;Karpas-707: 25.2;RPMI-8226: 16.3" "Low region specificity" "Detected in all" "HPA006162, HPA067493" Enhanced Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Mitochondria "HPA006162: AB_1857403, HPA067493: AB_2685851" "unprognostic (8.15e-3)" "unprognostic (2.25e-3)" "unprognostic (3.90e-3)" "unprognostic (5.72e-4)" "unprognostic (5.66e-2)" "unprognostic (3.33e-4)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (6.05e-2)" "unprognostic (1.12e-3)" "unprognostic (3.89e-2)" "unprognostic (2.88e-1)" "unprognostic (1.20e-9)" "unprognostic (9.12e-2)" "unprognostic (8.50e-2)" "unprognostic (3.66e-1)" "unprognostic (9.30e-3)" 1.7 0.8 0.7 25.0 0.8 6.6 1.2 0.8 1.6 0.6 1.0 3.5 2.9 0.9 0.8 0.9 0.7 2.9 0.6 0.8 1.1 0.9 1.6 4.4 54.6 1.8 1.2 0.4 0.3 0.2 0.6 1.2 1.5 0.9 3.9 1.0 2.6 0.5 0.2 1.6 15.6 1.0 1.3 27.8 5.1 1.5 2.1 6.8 1.3 0.1 55.8 4.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 2.4 0.0 0.3 31.1 0.0 0.0 5.2 0.0 0.0 0.1 1.8 52.4 0.0 0.0 0.0 0.6 0.2 4.4 0.1 0.5 0.0 0.5 0.6 0.4 0.0 0.3 0.0 25.2 0.6 0.0 0.0 1.5 1.3 0.0 0.0 0.1 2.8 16.3 8.8 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.1 0.3 1.3 0.0 0.0 9.2 4.0 1.1 2.2 0.7 0.0 0.1 3.5 12.0 23.1 7.3 25.6 97.5 22.8 25.3 8.3 71.0 11.5 15.0 33.4 15.1 10.6 0.5 22.5 10.6 0.7 0.8 0.8 1.6 0.8 1.1 1.8 1.2 1.5 1.3 2.1 1.5 1.6 0.0 2.3 3.9 149.9 0.9 0.0 0.2 0.0 0.7 0.3 0.5 0.5 0.0 0.8 0.0 8.4 0.1 37.4 0.1 0.0 0.0 17.2 0.5 0.2 1.1 0.0 9.7 5.0 0.0 0.2 0.8 1.5 0.1 0.0 0.2 2.2 0.9 11.4 0.0 5.0 0.1 0.0 8.4 8.6 4.8 0.0 13.2 7.2 26.2 13.7 0.5 50.4 2.5 2.8 0.1 0.1 1.2 77.2 0.1 0.0 0.4 2.4 1.7 0.0 0.2 1.0 1.2 0.4 0.7 1.1 0.3 62.1 0.3 0.2 0.2 SP140L ENSG00000185404 "SP140 nuclear body protein like" Q9H930 2 230327184-230403732 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA055864 Uncertain Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA055864: AB_2682949" "unprognostic (1.44e-2)" "unprognostic (8.91e-2)" "unprognostic (4.44e-2)" "unprognostic (9.70e-3)" "unprognostic (2.07e-1)" "unprognostic (1.42e-2)" "unprognostic (1.22e-3)" "unprognostic (1.77e-1)" "unprognostic (3.87e-1)" "unprognostic (2.31e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-1)" "prognostic unfavorable (5.09e-10)" "unprognostic (9.15e-2)" "unprognostic (7.81e-2)" "unprognostic (9.49e-2)" "unprognostic (2.00e-3)" 9.4 9.7 3.4 18.8 3.6 13.6 8.5 3.2 3.9 7.6 4.5 8.5 11.0 7.1 6.4 7.7 7.8 8.6 5.3 3.2 3.6 9.6 15.1 11.3 24.8 5.0 4.1 11.8 4.4 1.6 3.4 10.6 4.6 6.9 9.4 1.9 12.5 6.0 5.1 3.0 16.3 6.5 4.0 25.6 8.9 1.7 4.6 12.8 5.4 4.4 20.2 10.7 8.3 4.7 13.6 2.4 3.1 9.6 15.8 17.2 17.2 19.7 22.6 16.0 25.5 1.3 15.3 10.3 20.2 15.4 28.4 2.3 0.0 14.1 26.0 27.1 0.1 18.5 11.1 10.0 29.7 15.1 19.9 14.4 7.6 23.6 15.4 13.7 23.7 15.5 4.5 9.4 29.0 7.5 22.7 21.2 10.7 9.1 7.0 7.8 28.9 8.3 14.5 16.9 0.6 2.9 4.7 9.5 11.2 19.0 14.2 15.9 26.1 14.2 10.5 8.2 15.2 13.7 9.2 14.8 18.9 15.4 25.2 21.4 7.7 4.1 15.4 10.7 18.7 29.5 14.1 12.5 8.3 32.6 19.5 17.4 7.4 23.0 12.5 3.3 9.7 9.6 3.4 3.6 3.2 3.9 3.2 3.6 5.0 4.1 4.6 4.0 4.6 4.7 30.5 32.1 35.6 1.6 58.8 1.9 13.8 14.6 1.8 2.7 9.3 9.1 4.2 11.5 21.7 16.5 18.8 9.9 40.4 16.8 0.0 22.5 16.3 7.2 16.9 23.3 3.6 9.9 2.4 18.3 17.6 14.6 23.0 14.3 42.3 18.7 13.9 9.4 20.4 0.0 2.0 10.4 16.2 17.1 11.4 5.9 4.4 23.9 5.4 29.0 13.9 1.8 49.4 2.5 1.4 20.0 20.3 8.2 33.7 10.3 14.5 3.3 28.3 1.7 6.6 18.8 14.0 0.8 1.9 7.7 2.6 11.9 47.1 31.7 8.5 23.2 SP100 ENSG00000067066 "SP100 nuclear antigen" P23497 2 230415942-230545606 "Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 255.0" "Low region specificity" "Detected in all" "HPA016707, HPA017384" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" "Nuclear bodies" Nucleoplasm "HPA016707: AB_1857398, HPA017384: AB_1857399" "unprognostic (8.04e-3)" "unprognostic (1.08e-2)" "unprognostic (3.34e-2)" "unprognostic (1.86e-3)" "unprognostic (5.48e-2)" "unprognostic (1.12e-2)" "unprognostic (1.44e-1)" "unprognostic (2.77e-2)" "unprognostic (6.25e-3)" "unprognostic (5.32e-3)" "unprognostic (1.11e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.96e-2)" "unprognostic (1.48e-2)" "unprognostic (2.33e-2)" "unprognostic (3.25e-2)" 66.3 53.1 11.0 65.5 12.3 189.2 53.8 11.3 17.9 42.4 20.7 46.1 46.1 35.1 30.8 29.4 34.9 55.9 52.9 10.9 14.0 46.0 60.9 72.4 94.3 19.6 14.3 44.3 41.1 10.5 18.3 54.5 16.7 34.9 36.1 2.5 72.7 33.0 24.3 35.7 60.4 38.7 16.2 78.8 47.9 9.2 16.5 54.2 41.0 32.1 81.6 56.1 37.1 17.1 56.9 16.9 0.8 7.5 80.8 123.2 13.3 70.3 151.0 162.4 255.0 10.6 67.9 22.9 57.0 77.0 103.0 25.9 0.8 66.6 120.7 55.2 1.9 41.8 27.9 24.0 120.0 47.3 51.4 105.6 38.8 79.8 71.4 120.2 125.1 18.9 23.9 37.9 61.7 15.9 32.0 57.6 2.4 25.6 25.6 24.4 40.7 18.2 45.9 45.3 0.4 0.7 30.0 9.5 130.3 2.8 9.1 48.3 140.3 78.7 21.4 49.4 41.8 50.3 16.0 59.8 71.6 54.8 38.1 149.7 84.4 115.8 116.3 74.9 93.9 152.0 113.0 102.4 64.6 160.5 107.5 95.3 284.6 119.8 106.0 67.0 116.0 110.1 11.0 12.3 11.3 17.9 10.9 14.0 19.6 14.3 16.7 16.2 16.5 17.1 171.9 153.8 56.6 0.3 236.6 70.7 71.2 96.5 49.5 0.6 31.2 36.7 72.3 42.9 74.4 33.1 2.1 32.9 150.6 50.5 43.0 102.9 4.7 61.6 58.3 122.7 9.0 66.9 0.6 105.5 69.4 77.9 46.4 58.9 56.8 39.3 73.5 34.5 81.0 0.0 0.7 32.5 63.1 72.9 70.9 4.8 46.6 104.1 71.2 140.5 114.3 0.2 128.8 4.5 4.8 89.7 56.9 52.6 95.6 74.2 72.8 45.4 68.4 0.8 39.5 61.2 65.9 0.8 1.1 28.4 68.2 16.1 151.5 74.0 25.2 73.7 CAB39 "CGI-66, MO25" ENSG00000135932 "Calcium binding protein 39" Q9Y376 2 230712842-230821075 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 188.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037112, HPA076632" Approved Approved Nucleoli,Cytosol NA NA 100000 "Cluster 15: NK-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli Cytosol "CAB037112: AB_1078367, HPA076632: " "unprognostic (4.36e-3)" "unprognostic (1.42e-1)" "unprognostic (2.17e-2)" "unprognostic (1.71e-1)" "unprognostic (3.19e-1)" "unprognostic (4.73e-2)" "unprognostic (2.50e-2)" "unprognostic (2.84e-2)" "unprognostic (9.16e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (1.04e-1)" "prognostic favorable (9.05e-6)" "unprognostic (1.59e-1)" "unprognostic (2.92e-1)" "unprognostic (8.93e-2)" "unprognostic (1.36e-1)" 43.7 31.0 30.1 55.2 32.9 50.9 29.6 31.5 40.6 26.5 29.3 53.7 48.0 30.7 35.0 55.8 30.0 41.3 55.6 34.3 33.9 54.1 38.6 40.0 58.0 36.5 34.5 29.2 33.1 42.5 17.1 35.5 36.4 39.9 56.0 45.6 34.4 31.2 188.5 34.3 51.2 40.4 34.0 38.0 46.2 41.3 33.6 45.1 37.3 127.8 59.1 49.4 30.5 39.5 131.6 30.0 39.8 34.0 48.2 59.8 45.3 73.7 91.8 45.4 47.2 36.6 140.0 33.8 56.5 64.5 76.5 59.1 44.8 138.5 91.9 142.1 35.1 90.5 36.9 39.5 40.9 126.6 100.8 42.5 79.1 58.5 128.4 51.8 57.1 46.1 153.9 30.3 43.8 45.6 59.1 77.9 39.8 53.4 52.0 67.8 59.3 33.5 84.6 104.9 43.2 26.4 55.2 68.2 59.9 44.7 16.9 72.4 73.1 63.9 24.3 68.2 61.0 39.0 31.8 53.8 45.4 72.4 53.4 4.0 3.6 6.0 4.7 4.4 4.8 3.0 5.8 6.1 3.0 2.4 4.7 6.5 10.3 9.3 4.3 2.2 6.2 2.4 30.1 32.9 31.5 40.6 34.3 33.9 36.5 34.5 36.4 34.0 33.6 39.5 41.6 64.1 37.5 42.1 29.6 97.8 44.2 23.0 23.3 14.4 28.3 18.9 69.1 17.2 30.5 51.5 33.3 20.8 32.3 162.5 29.4 26.0 12.0 41.4 25.2 29.6 20.4 32.0 85.1 32.7 18.7 24.1 28.5 39.5 20.3 16.6 28.2 29.3 56.8 28.6 69.3 48.5 24.4 81.2 72.4 13.5 17.4 66.2 30.2 93.7 49.6 39.6 29.9 58.8 64.3 72.3 62.4 32.0 37.0 84.4 54.6 39.8 55.6 40.5 13.1 27.5 27.3 30.8 29.5 31.2 85.1 23.1 52.0 18.9 34.8 88.6 ITM2C "BRI3, BRICD2C, E25, hRPC.1050_D_4, ITM3" ENSG00000135916 "Integral membrane protein 2C" Q9NQX7 2 230864639-230879248 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1106.2;intestine: 707.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2610.8;Intestinal goblet cells: 884.1;Paneth cells: 2076.6;Plasma cells: 1010.4;Undifferentiated cells: 843.5" "Cancer enhanced" "Detected in all" "glioma: 496.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 2464.2" "Lineage enriched" "Detected in all" 8 "dendritic cells: 2464.2" "Cell line enhanced" "Detected in many" "EFO-21: 517.7;NB-4: 599.8;RPMI-8226: 482.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 29000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (2.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.81e-4)" "unprognostic (3.74e-1)" "unprognostic (6.03e-2)" "unprognostic (1.22e-1)" "unprognostic (1.03e-2)" "unprognostic (4.44e-2)" "unprognostic (3.45e-2)" "unprognostic (1.94e-2)" "unprognostic (1.04e-1)" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (2.52e-2)" 42.5 89.0 861.0 116.0 900.6 109.6 31.4 710.8 1106.2 116.8 553.9 707.6 80.2 103.5 40.0 84.4 58.6 54.0 57.4 854.3 996.3 177.3 36.7 45.3 78.2 928.0 960.3 78.1 80.3 105.5 288.4 108.8 800.9 103.4 539.0 118.3 72.3 110.2 22.4 20.4 329.3 95.3 909.4 117.5 87.5 22.1 1082.7 178.6 52.9 33.8 72.1 124.2 74.9 840.3 34.1 67.0 215.6 170.6 27.2 15.3 68.8 176.0 191.6 92.5 144.2 89.7 46.8 0.4 517.7 126.3 94.9 16.8 127.2 25.6 58.1 328.3 109.0 44.7 33.6 119.1 96.0 81.1 180.9 131.4 24.7 83.6 8.2 33.8 3.5 76.8 43.6 108.3 35.5 53.0 59.3 599.8 263.5 184.0 58.8 85.2 37.0 482.9 123.5 200.8 11.8 329.4 85.8 10.3 207.4 220.7 17.0 455.6 2.9 39.6 114.4 70.5 50.0 0.7 9.1 4.6 124.6 70.1 336.5 76.5 3.6 291.0 12.5 1.8 33.2 185.2 39.7 33.1 68.9 94.7 38.1 31.6 6.9 52.0 0.6 2464.2 64.2 50.0 861.0 900.6 710.8 1106.2 854.3 996.3 928.0 960.3 800.9 909.4 1082.7 840.3 26.3 6.4 10.8 155.7 167.8 24.1 49.7 9.3 29.0 428.1 24.4 40.0 20.5 61.5 16.5 138.0 252.3 95.7 483.6 2610.8 27.4 123.0 0.8 43.0 34.0 36.2 408.3 8.4 49.3 39.5 63.4 94.9 21.4 45.6 183.9 41.6 16.4 14.8 80.1 101.0 63.3 884.1 12.2 7.5 108.9 3.4 54.3 26.0 202.7 27.2 70.9 225.9 3.1 107.5 17.8 46.2 2076.6 69.2 1010.4 52.9 666.0 23.7 16.5 101.1 138.1 30.9 108.6 4.8 20.5 3.8 14.9 57.6 75.3 37.9 843.5 97.7 GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;lymphoid tissue: 4.4;testis: 4.7" "Cell type enhanced" "Detected in some" "B-cells: 2.1;Enteroendocrine cells: 1.8;Excitatory neurons: 2.3;Langerhans cells: 3.1;Plasma cells: 2.4;T-cells: 4.2" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 4.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 5 "Karpas-707: 32.0" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" 0.2 0.0 0.3 1.8 4.6 0.2 0.5 0.0 0.5 0.1 0.0 0.8 1.3 0.1 0.0 0.5 0.1 0.5 0.1 0.3 0.4 0.0 0.2 0.5 2.9 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.8 0.0 1.0 0.2 0.0 0.4 2.2 0.1 0.0 4.1 0.7 4.7 1.0 1.9 0.1 0.0 4.4 0.9 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.0 0.0 0.0 6.5 0.0 0.2 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.8 32.0 0.0 0.0 0.2 0.9 0.7 0.0 1.0 0.1 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 6.0 0.0 0.0 2.3 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.3 0.1 1.9 0.1 0.9 0.2 0.9 0.1 0.7 1.3 1.7 0.3 4.6 0.0 0.5 0.3 0.4 0.1 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.3 2.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.8 0.0 0.0 0.1 1.8 0.0 2.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.4 0.0 0.1 0.0 0.1 1.4 0.0 0.3 3.1 0.9 0.0 1.2 0.0 1.0 0.9 0.0 1.0 0.5 0.1 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.2 0.1 0.2 0.1 SPATA3 TSARG1 ENSG00000173699 "Spermatogenesis associated 3" Q8NHX4 2 230990324-231025055 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 179 "testis: 176.7" "Cell type enriched" "Detected in some" 6 "Late spermatids: 5258.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018254 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA018254: AB_1857419" "unprognostic (6.94e-3)" "unprognostic (6.98e-2)" "unprognostic (9.62e-2)" 0.0 0.0 0.4 0.0 0.5 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 176.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.4 0.5 0.5 0.5 0.6 0.4 0.2 0.9 0.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 783.7 0.0 0.0 1.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5258.5 22.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 23.9 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 PSMD1 "P112, Rpn2, S1" ENSG00000173692 "Proteasome 26S subunit, non-ATPase 1" Q99460 2 231056845-231173116 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 247.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021092, HPA036736, HPA036737" Enhanced Approved "Nucleoplasm,Actin filaments" NA NA 230000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Actin filaments" "CAB021092: AB_10123242, HPA036736: AB_2675278, HPA036737: AB_2675279" "unprognostic (9.32e-3)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (3.81e-2)" "unprognostic (2.71e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (8.63e-12)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.57e-1)" "unprognostic (1.72e-2)" "unprognostic (3.09e-3)" "unprognostic (2.49e-1)" "unprognostic (8.91e-3)" "unprognostic (1.10e-2)" "unprognostic (6.26e-2)" "unprognostic (4.16e-2)" "unprognostic (1.70e-3)" 37.3 38.2 21.9 31.7 26.1 20.1 29.0 21.9 33.7 26.3 20.9 34.8 35.5 37.4 25.6 41.5 24.3 20.3 51.3 27.5 28.5 34.1 42.1 27.0 28.8 26.9 24.9 19.2 17.3 72.7 32.9 36.8 28.3 29.7 36.8 25.4 25.8 33.4 136.3 34.9 29.3 44.9 24.5 25.2 27.9 29.0 24.5 36.6 27.4 81.6 38.3 37.3 27.8 24.4 103.9 113.1 120.6 93.8 122.2 88.7 115.4 135.3 139.4 133.4 134.0 136.5 97.6 80.0 123.3 150.5 138.0 95.0 169.4 125.0 174.3 124.3 93.3 148.7 81.6 155.5 62.9 133.3 119.4 76.5 57.8 142.4 73.9 73.4 159.6 70.3 212.1 56.8 158.7 100.3 103.0 68.3 157.8 100.1 89.3 86.0 190.4 77.7 96.5 104.0 78.8 74.1 108.7 94.1 65.7 120.6 75.3 74.7 152.3 101.4 110.8 126.0 129.8 48.6 80.2 140.4 162.7 100.0 123.4 34.6 27.8 18.8 25.1 39.0 27.3 21.0 25.8 23.8 30.9 17.2 19.2 22.9 12.5 35.9 42.5 18.9 32.3 25.7 21.9 26.1 21.9 33.7 27.5 28.5 26.9 24.9 28.3 24.5 24.5 24.4 51.9 51.3 48.5 77.7 32.9 33.1 37.7 57.0 19.9 46.4 23.0 25.8 125.4 31.5 53.0 33.1 41.7 119.2 27.0 63.6 17.6 83.9 6.2 51.2 67.5 51.7 39.4 61.6 100.0 102.2 101.4 54.6 42.3 60.9 103.9 67.8 30.0 86.9 72.3 90.9 96.0 30.0 57.0 44.2 23.5 9.9 34.8 49.8 17.8 54.4 62.6 46.6 29.9 67.3 93.1 98.6 26.2 45.9 49.4 46.5 46.9 32.1 66.9 53.2 72.3 54.6 128.2 247.9 158.8 39.2 33.1 167.5 36.6 65.5 42.9 38.8 HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 17.4;cervix: 21.5;endometrium 1: 18.8;smooth muscle: 16.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Endometrial stromal cells: 17.7;Endothelial cells: 4.1;Hepatic stellate cells: 5.7;Microglial cells: 4.7;monocytes: 6.2;Peritubular cells: 5.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "basophil: 1.8;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.8;T-cells: 1.0" "Group enriched" "Detected in some" 4 "HHSteC: 8.7;HSkMC: 16.5;SK-MEL-30: 32.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "HPA012867: AB_1856710, HPA063658: AB_2685079" "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" 0.9 17.4 0.4 1.5 0.4 1.2 0.8 0.9 0.6 21.5 1.2 9.0 1.5 18.8 11.8 0.7 2.4 1.2 4.7 0.4 0.6 3.4 3.6 0.9 1.0 0.5 0.4 0.8 0.2 0.6 0.3 4.1 0.5 0.3 2.1 0.2 0.5 1.4 0.1 0.1 4.8 16.8 0.2 0.4 4.5 0.4 0.4 1.2 3.2 0.3 0.8 2.2 0.8 0.6 0.2 0.3 0.0 0.1 0.5 4.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 8.7 0.1 0.3 16.5 0.0 0.0 0.0 0.0 3.2 1.4 0.1 0.0 0.0 0.2 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 32.7 0.0 0.0 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.4 0.4 0.9 0.6 0.4 0.6 0.5 0.4 0.5 0.2 0.4 0.6 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.0 0.2 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.2 1.5 17.7 4.1 0.0 0.0 0.7 0.7 0.1 0.8 0.0 3.4 0.0 0.1 5.7 1.5 3.4 1.7 0.9 0.0 0.0 0.8 0.0 0.2 0.6 2.2 0.0 4.7 6.2 0.0 1.0 0.5 0.6 0.2 0.0 5.3 0.0 0.0 0.0 0.0 2.0 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.3 0.2 0.3 0.0 0.2 ARMC9 "ARM, FLJ12584, KIAA1868, KU-MEL-1" ENSG00000135931 "Armadillo repeat containing 9" Q7Z3E5 2 231198546-231376848 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 48.6;retina: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 310.6;Excitatory neurons: 112.5;monocytes: 116.4;Rod photoreceptor cells: 202.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 15.5" "Immune cell enhanced" "Detected in some" "NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 275.2;SK-MEL-30: 222.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019041, HPA026671" Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA019041: AB_1845035, HPA026671: AB_1845036" "unprognostic (2.90e-1)" "unprognostic (2.86e-1)" "unprognostic (5.35e-2)" "unprognostic (6.26e-2)" "unprognostic (1.99e-2)" "unprognostic (5.57e-2)" "unprognostic (7.20e-4)" "unprognostic (1.58e-2)" "unprognostic (4.85e-2)" "unprognostic (7.17e-3)" "unprognostic (4.14e-1)" "unprognostic (9.15e-2)" "unprognostic (7.43e-2)" "unprognostic (1.30e-2)" "unprognostic (4.19e-2)" "unprognostic (5.57e-2)" "prognostic unfavorable (7.66e-5)" 2.3 15.0 4.0 5.4 5.3 1.9 3.3 1.1 15.5 5.6 48.6 14.7 1.7 19.5 5.6 4.2 8.7 7.7 2.3 5.9 1.9 5.2 0.8 7.1 1.6 0.4 2.4 9.4 3.7 10.8 11.1 5.7 0.1 5.5 5.2 71.5 3.2 6.6 1.0 2.6 6.5 23.5 0.0 1.1 8.9 9.4 0.2 3.0 7.6 1.1 2.1 6.8 2.7 1.7 21.2 10.8 20.3 15.1 14.5 23.7 8.3 23.3 275.2 28.6 35.8 3.1 10.3 2.7 11.0 68.3 46.6 12.2 24.8 22.7 25.0 1.7 15.2 1.5 14.0 11.6 41.3 5.0 5.1 63.8 8.8 38.3 13.7 73.3 21.7 12.2 4.7 0.6 46.0 29.9 6.3 6.9 44.4 7.7 12.0 7.8 18.2 0.3 30.6 6.9 15.6 32.2 9.3 25.2 222.7 17.8 9.7 5.4 22.6 17.6 10.9 10.0 10.4 24.8 6.2 1.3 33.9 1.0 17.7 1.1 0.2 0.3 0.2 0.1 0.1 0.6 0.2 0.3 0.2 0.3 0.3 0.3 0.5 2.6 0.2 0.3 0.2 0.2 4.0 5.3 1.1 15.5 5.9 1.9 0.4 2.4 0.1 0.0 0.2 1.7 1.3 3.2 36.1 25.8 1.4 1.8 5.6 6.8 1.2 24.0 5.1 5.7 3.3 2.8 7.5 3.7 310.6 4.8 0.1 4.0 1.9 7.3 69.5 25.1 22.3 4.9 7.8 1.3 112.5 17.3 3.0 7.2 3.6 4.1 3.8 6.6 2.5 1.0 10.6 1.7 62.7 6.0 0.0 0.3 2.4 23.8 14.0 6.6 19.6 17.8 116.4 16.7 1.0 25.6 14.1 11.5 1.8 21.4 1.1 1.9 0.7 5.1 31.3 202.4 6.6 5.3 6.4 36.7 15.7 0.6 0.9 2.2 1.3 6.3 10.0 2.1 B3GNT7 beta3GnT7 ENSG00000156966 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7" Q8NFL0 2 231395710-231401164 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 272.8;Intestinal goblet cells: 145.2;Paneth cells: 126.4;Undifferentiated cells: 354.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 32.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 19.5;HEL: 15.6;THP-1: 14.0;WM-115: 23.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA013881, HPA035625, HPA035626" Enhanced Approved "Golgi apparatus,Mitotic spindle,Cytosol" "Intracellular and membrane" Yes NA 3600000 "Cluster 40: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Mitotic spindle, Cytosol" "HPA013881: , HPA035625: AB_10601118, HPA035626: AB_2674707" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (4.57e-3)" "unprognostic (1.46e-2)" "unprognostic (1.28e-2)" "unprognostic (2.69e-1)" "unprognostic (1.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.18e-2)" "unprognostic (5.82e-2)" "unprognostic (2.17e-2)" "unprognostic (7.77e-2)" "unprognostic (4.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.18e-1)" "prognostic favorable (6.00e-4)" "unprognostic (3.57e-1)" 3.1 12.9 5.9 2.8 5.1 14.2 3.8 4.0 5.8 2.5 4.6 56.2 25.2 1.9 6.8 2.9 4.6 14.0 4.7 5.6 6.5 2.2 1.2 15.3 1.6 6.0 7.0 16.7 25.4 14.3 8.8 5.4 5.3 3.2 71.2 2.1 7.5 4.4 0.4 5.0 28.4 2.3 4.3 5.1 35.6 1.3 7.3 2.4 8.4 0.3 1.5 3.7 0.6 5.4 0.7 2.8 0.3 0.6 0.1 0.2 1.0 0.2 1.1 0.1 0.1 1.4 19.5 2.2 5.8 0.3 0.2 5.1 0.2 0.0 0.1 0.3 0.5 15.6 0.5 0.9 0.1 0.1 0.8 0.1 1.4 0.2 0.3 1.1 0.2 0.4 0.5 0.4 0.1 0.9 0.2 0.7 6.3 7.7 3.3 0.3 0.1 0.4 0.6 1.7 0.5 0.8 0.3 1.7 0.7 6.9 0.6 14.0 0.2 0.4 0.4 0.2 0.2 2.3 0.9 0.7 0.3 0.2 23.7 0.7 0.1 0.7 2.9 0.5 0.5 9.9 0.1 0.4 6.5 7.0 0.1 0.7 0.2 32.1 0.6 3.1 0.2 1.0 5.9 5.1 4.0 5.8 5.6 6.5 6.0 7.0 5.3 4.3 7.3 5.4 0.9 41.7 30.2 0.3 8.7 2.3 1.7 8.7 0.0 0.4 5.2 2.5 1.1 95.8 29.7 1.8 2.1 0.6 61.7 272.8 0.0 16.1 0.4 13.3 2.2 4.7 103.0 0.4 0.5 84.3 64.9 2.3 51.5 18.5 9.5 17.3 3.3 0.2 11.2 0.0 0.4 145.2 18.3 10.1 38.6 1.2 1.5 9.7 3.6 0.0 2.9 0.5 10.3 55.3 0.2 69.8 126.4 8.2 5.5 11.6 93.2 0.4 82.2 1.8 0.0 0.5 2.3 0.9 1.4 0.0 2.7 2.1 10.0 0.4 354.6 16.2 NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: AB_670270, HPA023981: AB_1854688, HPA071110: " "unprognostic (1.91e-1)" "unprognostic (2.53e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.63e-2)" "unprognostic (2.72e-3)" "prognostic unfavorable (1.41e-6)" "unprognostic (3.74e-2)" "unprognostic (4.31e-3)" "unprognostic (9.78e-2)" "unprognostic (6.70e-3)" "unprognostic (6.07e-2)" "unprognostic (1.66e-2)" "unprognostic (2.57e-2)" "unprognostic (9.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.42e-2)" 212.0 192.8 128.8 226.0 146.3 301.4 228.7 129.1 139.6 180.0 114.1 183.6 160.7 205.2 150.2 228.8 173.2 132.2 164.3 115.9 152.3 166.2 218.5 147.4 289.7 148.8 141.5 258.2 209.0 258.9 115.9 203.4 140.4 155.4 219.2 147.1 157.0 160.9 350.9 197.1 157.4 201.0 137.9 176.3 164.7 126.2 142.1 347.0 198.4 228.2 329.0 271.1 169.1 143.9 718.3 691.8 715.7 640.1 485.7 592.0 823.0 790.4 497.2 690.8 628.2 1227.4 521.4 1083.7 608.6 651.0 892.6 719.5 1614.4 1059.9 1284.7 554.6 644.0 1587.3 605.9 1749.5 544.0 1930.4 632.7 513.5 613.2 872.3 1019.6 394.9 834.2 770.5 1745.4 378.6 760.5 1176.4 1443.2 1086.7 1202.0 728.7 435.9 1290.8 1452.0 918.4 583.8 959.9 749.0 502.0 555.8 704.5 706.9 625.7 476.8 985.3 686.3 611.4 626.7 714.5 1063.7 624.3 554.5 1885.9 467.2 1173.1 685.2 27.3 95.6 62.5 136.5 100.3 152.8 113.5 118.4 121.9 130.6 111.9 130.3 114.2 16.8 177.8 121.7 102.0 102.3 151.0 128.8 146.3 129.1 139.6 115.9 152.3 148.8 141.5 140.4 137.9 142.1 143.9 286.2 291.7 411.7 8.1 468.9 459.9 633.8 241.0 644.9 145.0 315.2 303.8 320.9 147.3 401.6 195.0 47.9 386.9 596.2 215.0 230.9 294.4 20.6 348.7 669.8 291.1 200.0 419.2 9.3 254.4 444.6 370.9 292.0 421.8 451.7 262.7 130.6 242.0 239.5 80.8 10.4 319.6 156.6 133.7 231.1 32.2 217.2 281.8 165.4 10.3 268.9 199.6 346.1 14.1 14.9 268.0 153.9 159.9 543.5 651.1 120.1 277.6 250.3 141.0 151.2 548.9 442.0 433.3 532.4 707.9 441.4 379.0 454.0 442.6 380.6 449.1 NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Cell type enhanced" "Detected in some" "dendritic cells: 13.7;Hepatic stellate cells: 7.9;NK-cells: 47.4;Rod photoreceptor cells: 17.2" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Group enriched" "Detected in many" 7 "gdT-cell: 18.1;MAIT T-cell: 4.6;memory CD8 T-cell: 8.8;naive CD8 T-cell: 5.2;NK-cell: 10.9" "Group enriched" "Detected in many" 19 "NK-cells: 10.9;T-cells: 18.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Uncertain NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 63: NK-cells & T-cells - Immune response" "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" 5.2 1.3 0.1 0.5 0.1 2.6 1.5 1.1 0.3 0.7 0.0 1.1 2.8 0.9 2.3 1.6 1.4 0.7 0.7 0.1 0.0 1.0 0.8 3.1 0.5 0.0 0.0 0.3 4.2 0.3 0.2 1.3 0.0 1.3 0.8 8.2 1.2 2.1 0.2 0.4 3.7 0.9 0.0 3.6 0.8 1.5 0.0 0.1 0.8 0.0 0.2 1.3 0.6 0.0 0.0 0.2 0.3 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.2 0.3 0.3 0.3 0.2 0.1 0.0 0.4 0.0 0.1 0.1 0.1 0.1 0.7 0.1 0.0 18.1 0.0 4.6 0.1 1.3 8.8 0.1 0.0 0.1 5.2 0.7 10.9 0.1 0.4 0.6 4.9 0.1 0.1 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 1.3 0.0 0.1 2.5 0.0 0.0 0.0 2.1 0.5 13.7 0.0 0.0 0.0 1.2 0.4 0.2 0.6 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.1 1.3 0.0 7.9 0.0 0.2 1.7 0.7 0.1 0.0 0.9 1.4 0.5 2.1 0.3 0.0 0.0 0.2 2.6 47.4 0.5 0.1 0.1 0.0 7.5 2.4 0.1 0.0 0.1 0.0 17.2 0.0 0.2 0.9 2.2 4.7 0.0 0.4 0.7 6.9 5.2 0.0 0.1 TEX44 "C2orf57, MGC35154" ENSG00000177673 "Testis expressed 44" Q53QW1 2 231592864-231594276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 923 "testis: 152.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049917, HPA056433" Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "HPA049917: AB_2680951, HPA056433: AB_2683131" "unprognostic (5.42e-2)" "unprognostic (3.90e-1)" "unprognostic (6.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 152.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTMA TMSA ENSG00000187514 "Prothymosin alpha" P06454 2 231706895-231713551 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA047183 Approved Enhanced Nucleoplasm,Cytosol No No 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" Nucleoplasm Cytosol "HPA047183: AB_2679972" "unprognostic (1.49e-3)" "prognostic favorable (6.56e-4)" "unprognostic (3.73e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (2.52e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (5.99e-2)" "unprognostic (1.56e-2)" "unprognostic (3.72e-3)" "unprognostic (2.35e-3)" "unprognostic (9.24e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (5.54e-2)" "unprognostic (6.07e-2)" "unprognostic (3.81e-3)" "unprognostic (8.64e-3)" 1203.7 522.8 832.1 1028.5 1020.8 2322.6 1026.6 865.2 1035.4 1185.1 644.5 1045.1 703.0 1110.9 698.4 1186.1 1022.9 565.9 541.0 779.9 898.4 1203.7 652.1 933.2 1396.2 952.9 933.7 1078.5 1090.3 481.3 398.6 688.1 919.2 722.6 985.0 437.1 765.6 604.7 305.9 1425.4 935.1 699.4 875.4 896.2 873.2 237.1 929.1 2059.3 1002.8 246.4 1523.2 896.5 999.1 1137.2 2436.8 1416.4 1990.8 1788.7 592.5 783.4 2037.5 1614.2 1346.2 1379.8 1436.6 1380.8 2759.6 3811.5 1795.4 1271.0 948.1 1252.2 2830.6 1992.5 1738.6 3027.0 2228.9 4906.7 1096.2 2266.8 732.6 5621.1 2018.0 1143.7 733.1 1226.2 1002.6 1307.0 2286.8 3049.7 2910.9 1573.5 1222.0 3433.7 7998.5 7671.0 3004.9 2381.4 1180.4 5426.1 1408.4 2601.9 1719.2 2116.3 4041.8 2483.3 1851.0 1833.5 1507.1 1552.9 1383.9 4430.2 1704.1 1154.2 2052.5 1429.4 1769.7 1887.9 999.3 7614.4 790.8 3401.9 1897.3 2067.1 1713.8 1146.7 1346.2 1695.8 1945.2 2776.6 1928.5 1640.8 1828.0 2438.2 2109.4 1808.0 321.7 1782.3 1957.1 1944.4 2506.6 4661.6 832.1 1020.8 865.2 1035.4 779.9 898.4 952.9 933.7 919.2 875.4 929.1 1137.2 3907.5 971.2 1529.2 49.6 4518.0 7745.0 3851.3 5347.3 5459.5 703.1 3534.0 3673.7 259.7 1974.5 2483.8 2273.2 294.0 2599.4 4054.7 1741.3 3785.9 3474.2 103.3 2713.9 3364.3 4186.4 1695.3 3942.3 37.4 4190.1 5153.9 2404.0 2340.5 3092.6 2928.1 2349.3 1940.1 1347.6 3134.5 812.6 40.9 3178.6 3733.2 3492.4 8474.1 201.4 1306.3 3470.5 3689.1 78.7 3334.5 2195.9 2988.7 40.7 282.0 3669.3 2492.8 1404.5 3523.3 4524.2 1624.2 3136.2 1925.7 934.2 1926.2 2766.5 4571.8 1157.6 2467.8 5778.6 7944.4 2734.1 4276.7 1312.4 3381.3 4052.2 PDE6D JBTS22 ENSG00000156973 "Phosphodiesterase 6D" O43924 2 231732433-231786272 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 211.9;Late spermatids: 147.9;Spermatocytes: 236.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037433, HPA037434" Uncertain NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA037433: AB_2675475, HPA037434: AB_10672490" "unprognostic (1.95e-1)" "unprognostic (2.33e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-3)" "unprognostic (7.07e-2)" "unprognostic (5.41e-2)" "unprognostic (1.15e-1)" "unprognostic (9.48e-2)" "unprognostic (3.91e-1)" "unprognostic (1.41e-1)" "unprognostic (1.69e-1)" "unprognostic (4.75e-2)" "prognostic unfavorable (4.02e-5)" "unprognostic (1.11e-2)" "unprognostic (1.80e-2)" "unprognostic (1.46e-1)" "prognostic favorable (4.97e-4)" 16.8 28.1 43.4 16.2 47.3 14.6 16.3 47.4 50.7 19.2 38.0 19.6 13.4 17.6 14.9 16.3 15.5 14.2 19.3 44.4 45.7 19.5 15.4 15.2 23.3 45.6 46.0 13.4 13.2 23.5 25.0 23.0 45.7 13.7 17.6 69.6 14.2 17.6 13.7 16.4 15.7 22.0 46.5 18.8 16.2 27.8 45.8 32.4 14.0 16.7 24.0 17.9 16.4 49.6 26.3 20.3 37.0 28.2 43.7 36.1 15.7 27.0 44.6 40.8 56.9 8.1 24.5 21.4 22.7 23.2 74.9 20.4 22.3 30.2 52.6 63.5 26.4 31.2 12.4 13.0 20.2 20.6 17.2 25.5 26.4 39.8 30.4 27.5 44.1 68.3 9.1 23.5 27.5 52.0 67.7 64.4 28.6 39.6 28.1 45.7 17.0 32.9 42.8 19.5 36.4 32.6 23.0 19.4 46.3 36.1 17.5 43.0 19.5 26.5 7.3 57.9 21.4 57.9 26.3 52.6 27.4 38.6 42.5 84.4 48.2 68.4 46.3 48.7 36.3 50.4 46.0 47.3 49.3 55.5 31.7 44.3 42.0 34.4 64.9 55.8 84.4 43.1 43.4 47.3 47.4 50.7 44.4 45.7 45.6 46.0 45.7 46.5 45.8 49.6 20.8 0.0 8.7 18.3 19.5 13.8 12.4 23.6 21.1 14.7 13.3 17.7 13.1 12.8 15.8 12.9 16.7 16.4 18.2 10.2 25.4 23.1 211.9 6.8 9.2 19.6 17.4 15.8 13.4 23.9 21.9 14.7 13.3 6.5 14.5 7.3 19.2 5.0 18.9 11.8 18.1 10.0 14.2 14.4 15.1 147.9 13.1 17.5 23.2 16.9 24.6 22.0 17.5 48.7 34.0 26.0 14.9 12.4 17.0 10.5 11.2 18.4 11.8 29.0 19.7 10.7 24.9 236.8 65.1 20.3 14.2 13.5 18.5 11.5 10.5 11.0 COPS7B CSN7B ENSG00000144524 "COP9 signalosome subunit 7B" Q9H9Q2 2 231781671-231809254 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034675, HPA034676" Uncertain Supported Nucleoplasm NA NA 44000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA034675: AB_10696360, HPA034676: AB_2674274" "unprognostic (3.21e-1)" "unprognostic (1.59e-1)" "unprognostic (6.25e-3)" "unprognostic (3.59e-3)" "unprognostic (3.50e-1)" "unprognostic (4.77e-2)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.19e-1)" "unprognostic (4.81e-2)" "unprognostic (1.89e-1)" "unprognostic (5.77e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (1.50e-6)" "unprognostic (2.37e-2)" "unprognostic (1.39e-1)" "unprognostic (6.64e-2)" "unprognostic (1.55e-3)" 10.8 15.6 16.5 11.3 17.6 11.7 11.3 16.3 26.3 16.7 14.3 15.1 6.9 14.2 10.6 12.7 15.1 8.1 10.8 17.0 16.4 11.9 14.6 11.6 17.8 16.0 17.4 13.8 11.5 19.8 15.5 15.0 17.3 14.9 15.1 9.4 14.1 14.9 13.6 17.0 13.3 16.7 16.2 17.5 15.9 20.5 16.8 22.9 13.9 12.8 22.3 13.9 13.8 18.4 24.8 20.9 31.7 33.5 22.1 27.8 33.9 19.8 18.6 31.5 37.3 35.9 26.6 23.4 21.2 24.3 38.1 19.5 45.6 36.1 46.8 40.3 42.3 46.2 17.9 51.4 23.8 49.1 25.0 19.4 36.2 35.2 25.8 28.6 36.4 58.2 51.7 18.6 30.2 31.8 49.7 40.0 48.5 24.8 22.0 54.6 38.8 25.6 24.2 21.1 34.2 28.5 18.6 15.8 35.4 44.9 20.1 39.6 23.6 22.9 22.1 26.8 27.7 29.9 26.9 65.0 22.0 34.2 23.4 12.6 8.4 4.6 12.3 9.9 12.1 13.3 9.6 11.4 12.5 13.3 13.1 9.4 1.8 15.8 13.7 9.8 10.5 11.5 16.5 17.6 16.3 26.3 17.0 16.4 16.0 17.4 17.3 16.2 16.8 18.4 10.6 16.0 11.3 28.1 17.1 12.4 12.2 24.0 18.2 13.8 16.7 16.5 6.7 10.0 15.2 16.5 10.4 24.2 19.7 8.6 13.7 14.1 54.6 10.7 10.1 11.1 23.3 7.6 14.8 9.3 20.5 12.3 9.7 9.0 5.7 18.1 14.6 7.9 15.1 13.5 14.3 15.7 18.3 12.7 9.7 14.9 18.0 10.1 12.4 14.0 18.6 9.5 35.0 18.1 17.8 13.7 9.5 20.3 13.5 12.5 10.4 9.9 11.4 18.3 13.1 8.3 13.5 43.3 61.4 16.5 8.1 17.8 16.5 21.1 14.3 12.1 NPPC CNP ENSG00000163273 "Natriuretic peptide C" P23582 2 231921809-231926396 "Predicted secreted proteins, Transporters" Osteogenesis "Hormone, Vasoactive" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 33.5" "Group enriched" "Detected in many" 8 "Basal squamous epithelial cells: 190.1;Skeletal myocytes: 264.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "medulla oblongata: 33.5;spinal cord: 30.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;NTERA-2: 3.9;SCLC-21H: 5.5;SK-MEL-30: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "medulla oblongata: 15.5;spinal cord: 12.5" HPA035362 Uncertain "Secreted to blood" NA NA 6140 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA035362: AB_10671103" "unprognostic (9.70e-2)" "unprognostic (4.45e-2)" "unprognostic (1.99e-1)" "unprognostic (1.06e-2)" "unprognostic (5.67e-3)" "unprognostic (1.52e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-3)" "unprognostic (9.81e-3)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" "unprognostic (4.06e-2)" "unprognostic (1.17e-1)" "unprognostic (6.58e-2)" "unprognostic (1.18e-1)" "unprognostic (3.72e-1)" "unprognostic (1.91e-1)" 0.3 0.1 0.8 2.1 0.9 1.3 0.7 2.8 3.4 1.3 0.0 4.1 0.1 0.6 0.0 3.2 2.6 0.0 5.3 2.0 3.9 0.2 0.0 0.0 1.4 33.5 4.4 1.3 0.1 0.0 2.7 0.2 4.8 4.3 0.2 2.4 1.1 0.4 0.7 0.6 0.9 0.5 30.9 0.4 2.4 0.2 4.6 2.9 0.5 0.1 2.0 0.2 0.4 6.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 1.0 0.0 3.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.5 0.3 0.2 0.2 26.1 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 2.8 3.4 2.0 3.9 33.5 4.4 4.8 30.9 4.6 6.5 2.1 0.0 0.0 0.7 1.3 3.4 27.1 5.9 190.1 1.1 6.5 18.3 1.9 0.0 0.1 11.0 10.4 0.2 0.6 4.2 0.0 1.1 0.3 3.6 1.3 1.6 3.5 0.0 0.0 0.0 0.0 10.9 5.6 4.8 0.0 0.3 0.0 0.0 0.1 0.0 1.5 3.2 0.0 0.0 1.7 0.0 0.3 1.6 1.8 0.0 2.5 15.2 0.0 0.0 1.3 0.8 3.1 0.0 5.8 11.5 0.0 0.0 0.0 4.1 0.0 264.2 2.0 1.2 7.0 13.2 1.1 0.3 1.7 0.0 2.9 3.1 DIS3L2 "FAM6A, FLJ36974, MGC42174" ENSG00000144535 "DIS3 like 3'-5' exoribonuclease 2" Q8IYB7 2 231961245-232344350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 93.4;Oligodendrocytes: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035796, HPA035797" Approved NA NA "Cluster 24: B-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA035796: AB_2674786, HPA035797: AB_10669978" "unprognostic (1.20e-2)" "unprognostic (1.12e-1)" "unprognostic (6.05e-2)" "unprognostic (2.40e-2)" "unprognostic (8.17e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (3.41e-4)" "unprognostic (2.21e-1)" "unprognostic (6.45e-2)" "unprognostic (3.26e-2)" "unprognostic (1.64e-1)" "unprognostic (1.63e-1)" "unprognostic (5.93e-2)" "unprognostic (2.16e-1)" "unprognostic (3.55e-3)" "unprognostic (3.02e-1)" "unprognostic (1.97e-1)" 8.9 10.2 10.7 7.8 11.1 10.5 10.7 14.2 12.8 13.9 13.2 10.4 7.0 11.3 9.2 16.3 12.7 7.7 10.1 10.6 11.1 12.3 10.7 9.6 10.5 11.8 10.7 14.6 11.3 12.3 12.1 9.2 11.1 13.1 8.5 15.3 10.4 9.0 9.1 15.7 9.4 8.9 9.1 11.3 10.6 14.1 11.9 14.6 15.1 7.3 9.6 11.3 12.3 15.2 12.6 13.1 19.8 11.8 11.1 11.4 18.8 11.5 11.6 12.8 11.8 10.9 17.1 10.5 9.5 12.3 17.0 15.3 11.7 15.2 13.3 16.9 12.9 16.2 15.7 22.4 10.3 14.7 15.7 9.0 16.7 11.1 11.7 13.3 16.6 17.0 17.6 7.2 11.1 16.9 20.4 27.8 13.6 12.0 6.9 17.1 24.4 9.6 16.0 21.4 15.9 23.2 10.1 20.6 14.3 13.3 11.3 18.3 16.3 16.5 17.0 14.5 12.9 19.3 10.0 11.8 12.5 10.6 15.8 0.1 3.7 3.0 4.8 4.3 5.1 4.8 4.3 4.4 3.8 9.2 4.5 5.1 0.4 4.0 3.4 5.7 5.1 2.3 10.7 11.1 14.2 12.8 10.6 11.1 11.8 10.7 11.1 9.1 11.9 15.2 12.9 3.2 9.1 64.6 19.5 9.9 17.8 11.4 19.9 33.7 7.9 7.4 9.3 11.5 17.4 12.9 66.7 14.2 9.0 13.0 3.9 15.1 82.3 23.7 15.7 12.1 8.4 12.0 82.6 10.6 14.2 10.1 12.2 13.7 1.3 22.8 10.0 7.4 8.6 40.4 93.4 10.9 12.2 12.8 8.7 30.7 10.5 9.7 5.4 42.2 10.6 15.4 20.6 57.8 150.8 15.0 10.2 10.5 11.1 10.0 11.0 10.9 19.0 56.0 19.7 22.2 11.6 20.6 13.0 15.0 9.7 9.9 17.0 15.5 13.8 15.6 ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.8;placenta: 34.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 12.8;Glandular and luminal cells: 5.0;Syncytiotrophoblasts: 6.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 381.0;SiHa: 103.6" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 34.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 42.9 0.0 0.1 0.0 0.1 381.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 103.6 35.3 0.0 3.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 6.7 0.1 0.2 0.0 0.0 ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 33.9;HaCaT: 24.9;SuSa: 38.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.7 33.9 0.0 0.0 0.0 0.0 24.9 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 138 "intestine: 141.2" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.7;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 4.8" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" NA NA 130000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 141.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 128.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 290.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 106.9;ovary: 99.7;pituitary gland: 27.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 33.5;Muller glia cells: 100.3;Peritubular cells: 21.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.9" "Region enhanced" "Detected in many" "hypothalamus: 106.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AN3-CA: 44.1;HeLa: 21.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "HPA067560, HPA069756, HPA077424" Approved Supported Approved "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (1.21e-2)" "unprognostic (1.06e-2)" "unprognostic (4.39e-1)" "unprognostic (4.62e-3)" "unprognostic (2.80e-1)" "unprognostic (9.96e-4)" "unprognostic (7.56e-3)" "unprognostic (1.22e-1)" "unprognostic (9.89e-3)" "unprognostic (8.49e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.24e-5)" "unprognostic (3.09e-2)" "unprognostic (3.68e-1)" "unprognostic (7.84e-2)" "unprognostic (5.45e-2)" 1.8 10.0 5.2 1.0 5.5 0.0 1.7 1.2 31.6 1.0 3.4 0.8 0.1 2.2 0.0 0.4 3.5 0.5 0.2 0.5 106.9 4.1 2.5 0.4 0.3 20.9 11.3 99.7 0.7 1.2 27.6 0.3 17.1 0.4 0.0 13.4 0.6 1.5 3.0 0.6 0.4 1.4 2.4 4.5 0.9 1.9 44.2 0.2 1.4 0.0 0.4 0.4 1.1 4.5 0.0 0.1 0.1 44.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.6 0.4 0.0 0.2 0.0 0.6 0.0 0.0 0.0 4.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 3.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.5 1.2 31.6 0.5 106.9 20.9 11.3 17.1 2.4 44.2 4.5 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 33.5 0.5 0.3 1.1 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.2 1.1 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 1.5 0.1 0.0 0.0 0.0 100.3 0.0 0.0 0.0 0.1 0.0 21.1 0.0 0.0 0.0 0.1 0.0 3.7 0.0 1.0 2.3 0.5 1.6 0.0 0.0 0.0 0.1 0.6 0.0 0.1 PRSS56 ENSG00000237412 "Serine protease 56" P0CW18 2 232520388-232525716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.0;retina: 5.3;skeletal muscle: 9.7" "Group enriched" "Detected in some" 10 "Early spermatids: 29.0;Muller glia cells: 45.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.2;colorectal cancer: 2.5;endometrial cancer: 1.4;melanoma: 2.1;urothelial cancer: 4.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Daudi: 1.0" "Group enriched" "Detected in some" 10 "basal ganglia: 1.8;olfactory bulb: 4.2" "Region enhanced" "Detected in many" "olfactory bulb: 14.9" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (3.26e-1)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (3.73e-3)" "unprognostic (2.28e-1)" "unprognostic (7.15e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 1.6 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.0 2.9 1.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 5.3 0.0 0.0 9.7 0.0 0.0 0.0 1.1 0.0 0.0 0.8 1.4 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 1.6 3.0 0.1 3.0 2.9 1.3 3.0 1.1 1.4 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 1.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 3.6 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHRNG ACHRG ENSG00000196811 "Cholinergic receptor nicotinic gamma subunit" P07510 2 232539692-232548115 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skeletal muscle: 32.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HSkMC: 2.7;RH-30: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (2.26e-1)" "unprognostic (8.97e-2)" "unprognostic (5.61e-2)" "unprognostic (1.92e-2)" "unprognostic (4.38e-1)" "unprognostic (4.86e-3)" "unprognostic (2.32e-1)" "unprognostic (1.06e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "unprognostic (4.18e-2)" "unprognostic (4.32e-1)" "unprognostic (4.19e-6)" "unprognostic (6.13e-2)" "unprognostic (8.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.24e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.1 32.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 32: T-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: AB_2677636" "unprognostic (2.48e-1)" "unprognostic (1.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.86e-1)" "unprognostic (2.58e-2)" "unprognostic (2.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (4.40e-2)" "unprognostic (6.86e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (3.77e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.21e-3)" 1.8 2.3 6.3 2.3 5.3 6.5 2.7 13.4 7.8 3.2 5.4 2.8 1.9 2.6 2.9 2.8 3.8 1.9 2.4 5.0 4.5 7.4 2.7 2.5 3.4 3.2 2.4 5.7 2.9 1.6 5.0 2.0 4.1 4.4 2.1 10.4 2.7 1.7 4.0 4.2 3.6 1.3 1.5 6.1 3.3 5.2 4.5 3.3 4.7 1.4 2.2 2.8 3.0 9.7 3.1 2.3 4.7 7.5 1.7 2.3 3.6 2.1 1.2 2.6 2.9 2.8 3.6 5.0 1.5 1.6 2.8 3.2 4.1 1.3 3.8 3.0 3.9 4.5 7.7 3.5 1.1 3.6 2.9 2.6 1.2 2.6 1.6 2.5 1.5 6.5 3.6 5.0 2.1 5.3 4.9 8.3 2.8 1.9 2.7 4.7 6.3 2.3 1.5 3.5 6.1 6.0 2.2 2.1 2.3 3.3 3.1 3.9 2.5 4.3 4.5 2.7 2.1 4.8 3.4 4.5 2.5 3.6 2.6 1.6 1.7 1.8 1.9 1.4 1.9 1.7 2.0 1.5 1.1 2.1 3.1 2.5 2.3 1.8 1.5 1.2 1.6 0.7 6.3 5.3 13.4 7.8 5.0 4.5 3.2 2.4 4.1 1.5 4.5 9.7 2.4 9.6 3.9 4.2 5.3 1.3 4.5 2.3 1.8 4.9 2.5 2.2 2.0 1.5 2.9 3.7 8.4 2.2 3.1 1.7 0.0 3.6 4.2 1.0 3.6 1.7 1.2 6.5 4.5 1.5 1.3 3.1 7.7 1.5 0.0 6.4 1.4 0.7 1.4 6.7 5.7 1.5 2.0 1.6 1.7 0.7 4.7 2.4 1.8 1.0 2.8 7.5 5.2 5.0 8.1 2.0 2.4 1.9 5.6 2.6 3.5 1.4 1.7 7.0 6.6 3.7 2.0 3.9 5.7 3.7 2.0 1.4 4.1 4.0 3.0 2.9 EIF4E2 "4EHP, EIF4EL3, IF4e" ENSG00000135930 "Eukaryotic translation initiation factor 4E family member 2" O60573 2 232550674-232583644 "Predicted intracellular proteins" "Protein biosynthesis, RNA-mediated gene silencing, Translation regulation" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 302.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019253, HPA077074" Enhanced Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria Cytosol "HPA019253: AB_1848092, HPA077074: " "unprognostic (3.44e-2)" "unprognostic (2.70e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-2)" "unprognostic (1.63e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.38e-4)" "unprognostic (1.42e-1)" "unprognostic (5.62e-3)" "unprognostic (1.42e-2)" "unprognostic (1.31e-1)" "unprognostic (1.21e-2)" "unprognostic (1.36e-2)" "unprognostic (7.74e-2)" "unprognostic (3.34e-3)" "unprognostic (1.88e-1)" "unprognostic (9.38e-2)" 40.8 35.9 27.8 52.4 29.0 58.3 43.0 29.2 34.3 35.4 26.9 67.4 50.6 41.6 36.9 51.9 33.2 42.8 38.3 28.1 29.2 63.9 93.2 45.2 49.2 30.4 28.7 33.6 40.8 36.2 24.5 56.9 31.5 34.8 77.2 34.4 38.8 31.8 153.1 50.2 52.5 56.1 27.1 42.5 51.1 42.2 29.5 41.9 36.2 62.5 61.9 47.3 34.3 31.1 104.9 99.5 108.7 79.3 83.4 110.2 161.9 144.9 88.3 101.9 107.8 109.8 100.3 109.0 39.0 151.6 116.7 88.6 128.2 131.2 128.9 98.6 122.0 146.6 97.4 149.9 98.8 213.0 130.7 103.1 98.1 105.5 78.5 102.8 172.1 53.0 139.0 34.7 118.7 201.4 83.1 171.0 174.3 124.1 83.5 73.2 231.7 72.3 209.6 133.2 98.7 135.5 77.0 86.6 95.3 117.2 81.3 145.3 148.6 88.3 114.9 96.6 106.1 67.3 71.0 139.8 100.0 109.4 78.9 299.2 205.7 194.4 63.6 220.0 51.4 62.2 65.8 67.7 179.3 60.5 55.1 56.1 132.1 70.7 205.9 70.9 114.7 155.5 27.8 29.0 29.2 34.3 28.1 29.2 30.4 28.7 31.5 27.1 29.5 31.1 37.2 41.7 57.3 11.8 40.1 38.0 78.2 127.4 31.3 19.8 41.5 49.3 36.9 65.8 85.4 35.0 18.8 142.0 53.6 109.1 74.3 164.5 129.6 45.6 63.1 46.9 66.0 50.7 20.0 151.5 204.3 60.2 48.9 68.6 43.7 47.2 50.0 119.9 125.4 20.2 19.3 111.3 120.1 90.8 87.5 302.4 38.2 72.6 30.2 10.3 135.8 29.3 51.5 12.1 29.7 159.8 109.3 38.7 51.8 96.8 139.1 170.8 58.8 22.3 26.3 38.8 118.5 68.4 56.0 59.7 51.1 182.5 42.7 92.3 87.9 120.4 EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682780 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 414.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 241.8;Breast myoepithelial cells: 129.0;Distal tubular cells: 393.2;Oligodendrocytes: 173.4;Sertoli cells: 197.2;Smooth muscle cells: 130.9;Syncytiotrophoblasts: 263.9" "Cancer enriched" "Detected in all" 5 "breast cancer: 100.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 125.8;RPTEC TERT1: 68.6;SK-BR-3: 301.8;T-47d: 236.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA 14000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: AB_2680716, HPA056959: AB_2683288" "unprognostic (9.51e-3)" "unprognostic (2.21e-2)" "unprognostic (4.78e-3)" "unprognostic (3.25e-1)" "unprognostic (3.40e-1)" "unprognostic (9.70e-2)" "unprognostic (9.02e-2)" "unprognostic (1.13e-1)" "unprognostic (3.29e-3)" "unprognostic (1.21e-1)" "unprognostic (5.57e-2)" "unprognostic (9.99e-2)" "prognostic favorable (2.93e-7)" "unprognostic (2.00e-2)" "unprognostic (1.84e-1)" "unprognostic (2.51e-2)" "unprognostic (2.29e-3)" 86.3 7.0 199.7 3.7 303.2 0.8 180.7 244.9 261.3 86.9 129.9 16.9 4.4 72.4 33.7 9.6 73.7 12.0 46.0 196.6 217.4 186.2 54.6 15.3 3.9 253.6 258.7 76.5 86.5 10.5 16.5 77.9 261.8 25.6 5.7 9.5 22.2 27.7 35.5 30.9 16.2 20.6 201.4 52.5 17.6 20.1 237.8 3.0 32.7 42.7 2.4 22.0 44.5 414.6 0.0 3.4 5.7 1.4 2.2 0.1 125.8 26.8 2.1 2.3 1.9 0.9 0.6 0.1 2.0 11.6 2.9 0.2 19.0 0.0 0.3 0.5 9.2 0.0 2.4 1.9 0.0 0.1 0.3 1.0 0.4 0.2 0.0 0.4 0.0 5.5 3.9 0.5 0.5 2.3 0.6 0.2 8.4 0.0 0.2 0.6 7.2 0.4 68.6 0.7 0.3 3.2 9.1 301.8 18.3 42.3 236.9 2.6 0.0 0.0 1.8 0.4 0.8 0.2 0.1 0.1 0.3 0.1 13.4 1.0 0.2 0.1 0.2 0.1 0.4 0.3 0.3 0.4 0.1 0.1 0.6 0.6 2.2 0.1 0.1 0.2 0.1 0.1 199.7 303.2 244.9 261.3 196.6 217.4 253.6 258.7 261.8 201.4 237.8 414.6 15.6 0.0 0.0 37.5 1.5 3.6 2.8 1.3 1.2 0.5 241.8 129.0 7.4 1.5 4.6 35.0 0.0 112.0 3.0 0.3 393.2 0.0 9.0 1.1 37.8 16.8 0.0 2.7 2.6 0.0 19.7 41.1 0.0 1.7 0.0 3.2 6.4 89.4 8.7 0.0 5.3 0.1 59.0 1.3 3.0 7.0 44.4 2.1 8.8 18.7 0.0 48.0 0.0 1.5 173.4 0.0 0.0 57.2 0.1 4.6 0.0 116.5 1.9 1.4 197.2 8.7 130.9 17.3 13.6 0.4 3.1 263.9 2.5 1.5 0.3 2.0 GIGYF2 "GYF2, KIAA0642, PARK11, PERQ2, PERQ3, TNRC15" ENSG00000204120 "GRB10 interacting GYF protein 2" Q6Y7W6 2 232697299-232860605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 333.8;Late spermatids: 563.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050899, HPA054612, HPA059918, HPA065064" Approved Enhanced Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "HPA050899: AB_2681267, HPA054612: AB_2682542, HPA059918: AB_2684160, HPA065064: AB_2685417" "unprognostic (7.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-2)" "unprognostic (1.92e-2)" "unprognostic (8.61e-2)" "unprognostic (8.39e-3)" "unprognostic (2.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.27e-2)" "unprognostic (7.40e-3)" "unprognostic (8.01e-2)" "prognostic favorable (6.97e-5)" "unprognostic (7.53e-2)" "unprognostic (1.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.66e-1)" 19.1 19.4 13.5 19.1 17.2 21.6 23.1 23.5 14.6 19.0 11.4 17.8 17.6 21.3 13.8 20.4 18.1 15.7 25.6 13.5 18.5 25.2 15.8 16.7 20.4 14.6 13.6 27.4 25.5 40.5 9.6 22.0 15.9 22.0 19.5 22.9 28.4 17.0 37.5 21.2 20.0 18.5 11.4 21.3 21.5 37.9 15.5 24.6 25.9 32.1 21.4 18.6 12.4 21.6 34.3 30.8 37.2 38.1 51.2 44.7 44.1 37.9 36.5 31.3 33.0 30.6 29.6 20.1 9.3 33.5 59.8 36.6 44.2 34.7 41.2 49.4 32.1 71.6 30.5 46.9 36.7 61.3 44.9 31.1 34.6 38.1 59.2 33.6 34.9 33.5 72.8 24.2 33.1 36.5 40.7 24.3 37.5 29.8 25.7 38.7 74.5 27.8 28.6 51.8 33.4 27.5 41.8 30.5 37.7 32.9 29.8 40.1 53.1 33.6 28.6 34.1 29.6 47.6 26.1 40.3 31.6 35.0 31.3 39.2 10.7 13.1 8.0 7.8 10.5 6.1 7.1 7.9 11.2 10.6 8.5 7.9 13.7 13.4 18.9 8.3 10.7 6.4 13.5 17.2 23.5 14.6 13.5 18.5 14.6 13.6 15.9 11.4 15.5 21.6 31.3 57.7 68.4 98.2 26.7 15.7 36.9 25.8 23.9 50.6 29.6 26.0 85.5 25.8 50.8 36.8 60.5 32.2 28.0 28.8 25.4 31.1 333.8 41.2 54.5 36.8 19.2 41.0 105.0 27.3 22.0 36.7 25.0 45.0 17.7 35.4 20.0 28.8 28.5 48.8 131.2 27.9 24.4 29.3 12.1 563.9 37.6 31.8 26.6 98.4 32.9 38.8 42.2 116.6 171.7 29.2 15.0 36.9 39.0 40.6 29.5 18.5 43.3 38.7 26.3 55.0 36.0 128.4 93.4 27.3 19.2 73.2 28.8 46.3 30.3 37.4 KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 159.5;intestine: 91.3" "Group enriched" "Detected in some" 4 "Muller glia cells: 54.8;Proximal enterocytes: 217.4;Undifferentiated cells: 68.1" "Cancer enriched" "Detected in some" 5 "melanoma: 5.9" "Group enriched" "Detected in many" 4 "cerebellum: 7.3;hippocampal formation: 8.0;thalamus: 5.3;white matter: 3.4" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "U-2197: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051609 Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nuclear membrane" "HPA051609: " "unprognostic (4.29e-2)" "unprognostic (2.00e-1)" "unprognostic (2.69e-1)" "unprognostic (9.03e-5)" "unprognostic (1.17e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (3.44e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (4.90e-2)" "unprognostic (1.86e-2)" "unprognostic (2.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" 0.1 0.1 0.4 0.0 1.3 0.4 0.1 7.3 1.1 0.1 159.5 0.1 7.9 0.1 0.3 0.1 0.0 2.2 0.1 8.0 0.4 3.3 0.2 0.1 0.2 1.3 0.8 0.2 0.8 15.8 0.2 0.0 1.3 0.1 0.0 13.7 0.2 1.1 0.1 3.2 91.3 0.1 0.4 0.1 2.3 0.5 5.3 0.1 7.0 0.0 0.0 0.1 0.2 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.3 0.0 0.2 0.2 0.1 0.0 1.9 0.3 0.3 0.3 0.0 0.4 0.2 0.6 0.2 0.1 0.3 0.7 0.3 0.3 0.4 0.4 0.3 1.0 0.0 0.4 1.3 7.3 1.1 8.0 0.4 1.3 0.8 1.3 0.4 5.3 3.4 0.1 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.5 0.0 0.5 0.5 0.0 0.0 1.8 0.0 0.0 0.2 0.1 1.9 0.0 3.0 0.7 0.3 0.2 0.0 0.0 1.1 1.3 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.2 25.7 0.0 0.0 0.0 0.6 0.0 0.1 21.4 0.0 0.0 54.8 0.0 1.5 2.0 0.0 8.8 0.0 0.0 0.1 217.4 0.2 0.0 1.7 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 68.1 0.0 SNORC "ASCL830, C2orf82, UNQ830" ENSG00000182600 "Secondary ossification center associated regulator of chondrocyte maturation" Q6UX34 2 232857270-232878708 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 55.0;breast: 14.2;skin 1: 32.2" "Group enriched" "Detected in some" 22 "Breast glandular cells: 367.0;Breast myoepithelial cells: 324.9" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 20 "basophil: 2.8" "Lineage enriched" "Detected in single" 20 "granulocytes: 2.8" "Cell line enriched" "Detected in some" 13 "Hep G2: 59.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA052824 Approved Approved Nucleoplasm,Nucleoli "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" "Nucleoplasm, Nucleoli" "HPA052824: AB_2681964" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (1.27e-1)" "unprognostic (2.11e-1)" "unprognostic (3.06e-1)" "unprognostic (4.71e-1)" "unprognostic (1.23e-3)" "unprognostic (3.52e-1)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (4.30e-7)" "unprognostic (1.83e-3)" "unprognostic (8.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.33e-2)" 1.3 0.9 6.7 0.2 14.1 0.5 14.2 21.2 8.5 0.7 0.2 3.3 0.9 0.7 0.5 1.0 1.2 0.0 0.8 11.9 23.5 1.3 7.4 0.8 0.6 37.8 14.8 0.7 1.7 0.3 1.6 0.2 28.3 1.5 0.3 0.6 4.7 0.1 1.0 32.2 1.7 0.1 38.2 1.1 0.8 8.1 14.2 0.1 0.6 0.0 0.0 0.9 0.8 55.0 0.9 0.0 0.3 1.4 1.0 1.6 2.4 0.3 0.0 0.3 0.7 0.0 0.2 0.0 0.7 0.1 0.5 0.5 0.0 0.0 0.0 0.6 2.1 0.5 0.4 59.6 0.8 0.1 1.7 0.0 1.3 0.4 0.8 0.7 1.6 0.6 0.1 0.2 0.2 0.2 0.2 0.5 0.0 0.0 2.2 0.4 0.6 0.4 0.1 0.9 0.2 0.8 0.4 0.0 2.2 1.0 0.1 2.6 0.9 0.2 0.8 0.8 0.8 3.8 4.7 0.2 0.1 1.4 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 14.1 21.2 8.5 11.9 23.5 37.8 14.8 28.3 38.2 14.2 55.0 3.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 367.0 324.9 0.0 0.0 0.0 1.8 0.0 0.1 10.1 0.0 5.9 0.5 0.0 3.8 0.4 6.3 0.0 0.0 0.0 0.8 0.1 2.9 0.0 2.3 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 2.3 0.9 0.0 0.0 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NEU2 SIAL2 ENSG00000115488 "Neuraminidase 2" Q9Y3R4 2 233032672-233035057 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "skin 1: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" CAB022336 Uncertain NA NA 25000 "Cluster 61: Skin - Cornification" "CAB022336: " "unprognostic (1.30e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.8;lymphoid tissue: 99.4" "Cell type enhanced" "Detected in many" "B-cells: 94.5;dendritic cells: 95.8;Kupffer cells: 65.6;Microglial cells: 181.8;NK-cells: 193.6;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 44.7;HEL: 94.6;HMC-1: 94.8;hTCEpi: 87.1;NB-4: 89.4;THP-1: 62.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016300, HPA070455" Enhanced Supported Cytosol No No 4400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "CAB016300: AB_628250, HPA070455: AB_2686267" "unprognostic (5.29e-2)" "unprognostic (2.05e-3)" "unprognostic (1.99e-2)" "unprognostic (6.71e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (2.29e-2)" "unprognostic (3.74e-1)" "unprognostic (2.56e-1)" "unprognostic (1.23e-1)" "unprognostic (1.14e-2)" "unprognostic (1.66e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (6.54e-2)" 15.5 5.8 6.7 19.8 7.3 32.7 11.4 7.6 6.5 9.2 6.7 9.5 3.7 6.3 2.8 7.5 9.2 6.0 8.2 6.0 8.5 9.5 6.5 25.2 34.1 10.8 9.4 3.2 3.1 1.2 6.9 8.4 11.2 11.8 4.7 0.3 26.3 2.9 3.9 7.9 50.8 3.5 9.3 99.4 6.3 3.5 10.4 14.5 7.8 1.7 31.9 9.8 8.4 10.3 0.1 0.1 0.6 0.0 0.0 0.2 4.8 0.1 0.2 0.1 0.0 0.0 1.2 17.9 0.0 0.0 0.0 0.1 0.0 44.7 0.1 15.4 0.2 94.6 0.1 9.0 0.7 28.7 94.8 1.6 87.1 0.3 9.6 0.3 12.7 2.6 0.4 8.0 0.4 0.0 13.2 89.4 2.9 0.0 0.1 27.5 0.1 6.5 0.1 5.5 0.1 0.1 0.0 1.7 0.0 11.1 0.0 62.9 10.7 0.0 1.5 0.0 0.0 0.2 5.2 26.7 0.1 36.5 0.2 13.2 10.8 11.4 16.0 15.8 10.9 14.0 7.1 12.0 12.3 12.6 5.8 8.4 10.3 12.5 20.0 6.1 10.5 17.9 6.7 7.3 7.6 6.5 6.0 8.5 10.8 9.4 11.2 9.3 10.4 10.3 18.1 3.2 15.5 3.3 94.5 1.7 1.6 5.4 9.1 0.5 3.2 5.8 3.6 4.3 5.2 3.7 0.0 0.6 95.8 1.1 0.0 0.5 13.0 0.8 0.3 20.8 0.0 35.7 2.6 0.5 0.8 1.7 2.0 0.5 15.2 0.1 15.0 2.2 29.2 0.0 1.1 0.2 0.0 65.6 17.1 13.4 0.0 51.5 0.0 181.8 51.4 0.0 193.6 4.0 1.8 0.4 2.5 1.2 34.0 0.6 0.1 0.4 5.7 0.0 0.0 2.0 1.7 0.5 1.0 3.1 1.1 1.1 60.6 0.1 0.5 1.5 ATG16L1 "APG16L, ATG16A, ATG16L, FLJ10035, WDR30" ENSG00000085978 "Autophagy related 16 like 1" Q676U5 2 233210051-233295674 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012577, HPA063900" Supported Approved Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" Cytosol "HPA012577: AB_1845155, HPA063900: AB_2685146" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "unprognostic (3.57e-2)" "unprognostic (2.22e-3)" "unprognostic (1.89e-1)" "unprognostic (4.49e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.85e-2)" "unprognostic (6.66e-3)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (3.93e-2)" "unprognostic (1.41e-1)" "unprognostic (2.41e-1)" "unprognostic (2.08e-1)" 7.6 7.8 7.0 3.8 7.5 14.3 8.8 7.9 8.4 8.1 12.8 11.1 5.0 9.6 5.5 11.6 7.1 3.3 10.7 7.3 6.6 9.2 15.1 7.6 5.8 6.5 6.3 8.5 8.6 5.3 5.5 4.0 6.9 12.1 5.2 5.6 11.5 4.3 19.9 17.2 11.1 5.2 6.3 11.5 11.1 13.5 6.5 5.9 11.2 6.1 5.2 11.5 8.2 7.7 13.3 12.2 4.9 8.5 12.4 8.0 14.0 11.4 9.3 9.6 8.9 8.9 9.7 3.1 3.7 8.9 14.3 7.7 9.8 6.4 9.8 6.2 7.7 7.1 9.1 14.6 9.1 5.6 9.0 5.3 9.1 11.5 8.7 7.2 9.0 4.7 7.6 2.9 10.2 9.3 6.7 11.2 19.1 14.1 17.6 4.8 10.3 2.6 9.9 8.4 8.8 6.5 7.8 8.5 8.5 7.4 5.3 7.1 10.7 6.2 5.4 9.6 10.3 6.5 3.9 6.1 10.5 5.7 10.2 0.0 1.7 2.9 4.8 1.4 3.7 2.0 3.1 4.4 1.4 2.2 3.5 3.5 1.2 4.1 4.7 0.7 3.8 2.1 7.0 7.5 7.9 8.4 7.3 6.6 6.5 6.3 6.9 6.3 6.5 7.7 6.1 6.4 8.2 5.2 7.4 9.1 4.6 5.2 3.4 8.4 12.0 6.6 5.6 7.2 11.6 5.5 4.2 4.6 20.9 13.9 5.9 8.3 1.2 16.4 10.9 6.4 9.0 3.8 31.0 6.7 6.2 5.2 8.2 31.8 9.5 6.4 6.1 10.2 5.6 1.7 25.6 5.1 6.1 6.3 5.7 1.7 4.1 5.1 10.6 8.4 6.6 7.1 4.1 11.6 21.4 16.8 8.0 3.8 8.1 7.1 9.2 5.6 11.5 19.5 6.6 5.8 6.9 11.0 17.6 7.3 13.2 3.7 19.2 5.1 8.4 6.0 SAG "ARRESTIN, RP47" ENSG00000130561 "S-antigen visual arrestin" P10523 2 233307816-233347055 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital stationary night blindness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 474 "retina: 1466.0" "Cell type enriched" "Detected in some" 5 "Rod photoreceptor cells: 6946.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA004946 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA004946: AB_2667304" "unprognostic (4.76e-2)" "unprognostic (1.94e-2)" "unprognostic (4.52e-3)" "unprognostic (3.95e-1)" "unprognostic (8.54e-2)" "unprognostic (2.89e-2)" "unprognostic (3.86e-2)" "unprognostic (2.26e-2)" "unprognostic (1.78e-1)" "unprognostic (4.54e-1)" "unprognostic (4.57e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-9)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-1)" "unprognostic (1.03e-5)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1466.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.3 1.6 0.2 0.0 651.7 0.2 0.3 1.0 0.0 0.0 0.0 869.5 1.5 0.7 0.6 0.0 0.0 40.4 0.9 0.2 41.6 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.1 338.2 0.5 0.0 0.0 1.5 2.3 121.5 0.9 0.5 0.0 0.0 0.7 1191.9 0.0 0.5 0.2 0.0 0.0 0.0 0.4 1.2 0.9 0.0 0.2 6946.1 13.1 1.7 0.4 2.1 1.6 0.0 0.6 0.4 0.9 0.1 0.2 1.2 DGKD "DGKdelta, KIAA0145" ENSG00000077044 "Diacylglycerol kinase delta" Q16760 2 233354494-233472104 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 30.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 143.2;Inhibitory neurons: 137.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 17.3;HeLa: 21.8;U-698: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027530, HPA049101" Approved Supported Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "HPA027530: AB_2672320, HPA049101: AB_2680630" "unprognostic (1.84e-1)" "unprognostic (2.19e-2)" "unprognostic (7.76e-3)" "unprognostic (1.92e-2)" "unprognostic (5.69e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (1.69e-5)" "unprognostic (2.25e-1)" "unprognostic (1.17e-3)" "unprognostic (6.03e-2)" "unprognostic (5.76e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (4.07e-8)" "unprognostic (1.78e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (5.94e-3)" 5.2 3.4 4.3 1.9 5.5 12.0 5.9 20.5 6.2 4.5 3.2 9.0 1.6 5.9 1.6 2.2 5.7 1.0 7.6 5.8 4.0 2.5 3.6 10.6 4.3 6.5 3.9 8.9 2.7 0.4 3.7 2.9 7.4 5.7 2.3 5.4 5.9 0.5 30.4 3.0 12.9 0.7 4.1 11.4 25.2 9.6 4.4 1.0 8.3 0.9 4.5 5.3 2.6 8.8 1.7 8.5 2.1 1.5 1.5 1.4 3.0 2.4 1.0 0.6 0.5 9.7 1.9 10.3 1.1 2.4 4.5 2.0 2.4 1.0 3.2 17.3 11.3 4.7 21.8 5.8 0.9 11.7 7.2 2.3 2.2 1.1 2.1 1.8 0.8 2.1 7.8 1.8 1.6 3.1 9.2 3.3 1.6 2.8 6.9 14.5 5.7 1.6 0.9 3.3 2.1 2.2 1.4 2.3 1.0 1.8 0.6 5.2 1.0 1.2 3.0 1.2 1.7 7.1 6.2 22.7 0.8 5.6 0.6 1.7 1.6 5.6 2.1 0.6 1.1 4.8 0.5 1.5 0.4 5.0 1.7 2.4 1.2 0.6 1.0 0.4 0.2 1.7 4.3 5.5 20.5 6.2 5.8 4.0 6.5 3.9 7.4 4.1 4.4 8.8 18.9 32.1 46.2 27.1 61.1 8.9 6.4 5.6 4.6 33.8 19.6 11.6 21.0 0.0 13.8 0.0 62.6 14.6 62.0 40.6 0.0 3.6 14.9 23.4 12.5 19.1 2.4 5.0 11.1 4.4 1.2 9.7 143.2 38.1 5.7 13.1 4.6 7.0 6.8 8.4 137.9 32.8 8.2 10.4 13.8 38.7 6.5 28.7 8.8 11.2 17.5 13.9 49.4 43.2 81.5 26.0 13.5 4.5 34.7 17.6 29.6 2.6 4.8 44.3 19.7 49.4 21.2 14.4 29.3 4.5 3.7 2.5 32.5 7.6 20.1 9.9 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 79.3;Oligodendrocytes: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Focal adhesion sites" "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 11.8 12.0 10.4 7.5 17.0 3.4 13.9 12.8 11.4 10.0 16.5 9.4 10.5 10.6 24.0 10.4 11.5 11.6 8.2 10.2 12.0 14.2 13.2 12.5 7.2 19.4 14.2 15.9 14.0 16.8 8.5 12.4 19.0 13.5 9.5 14.2 12.9 10.4 9.6 19.7 10.1 8.5 12.3 9.9 13.1 14.7 16.2 10.1 16.4 7.6 7.8 9.6 7.5 25.4 17.3 19.9 17.6 12.0 25.2 23.0 15.7 16.4 12.4 14.7 16.0 14.3 20.2 0.4 4.7 26.4 38.6 30.3 13.3 29.7 20.6 0.0 9.0 13.3 17.4 24.3 22.3 5.8 8.9 22.2 21.1 22.2 30.9 26.2 17.3 8.1 22.0 3.2 21.4 14.0 6.2 8.5 7.9 17.8 16.0 0.0 36.3 8.1 17.9 27.6 9.6 10.3 13.5 13.5 16.9 12.9 15.4 12.9 17.3 20.9 13.1 8.9 20.6 6.0 4.9 0.8 27.1 10.2 18.6 0.0 1.0 0.0 0.5 1.1 0.2 0.4 0.5 0.4 1.5 0.7 0.7 0.7 0.1 0.5 0.9 1.9 0.8 0.5 10.4 17.0 12.8 11.4 10.2 12.0 19.4 14.2 19.0 12.3 16.2 25.4 11.8 32.1 35.5 79.3 7.9 7.4 9.1 13.6 15.4 18.1 17.0 14.7 10.7 10.0 19.9 16.5 25.0 21.2 6.7 9.9 7.9 9.4 8.4 19.8 18.3 11.1 15.0 5.7 25.9 12.6 10.6 11.9 21.4 21.3 9.5 23.4 12.8 25.4 8.2 23.5 38.2 10.9 4.1 11.6 3.6 10.7 6.8 9.1 3.6 40.3 5.9 11.9 4.1 48.2 127.7 10.5 12.6 8.2 10.9 12.9 13.9 14.6 21.0 19.4 13.1 17.5 10.6 30.2 20.9 17.2 10.5 15.7 5.5 21.1 12.1 10.0 UGT1A8 UGT1H ENSG00000242366 "UDP glucuronosyltransferase family 1 member A8" Q9HAW9 2 233617645-233773310 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 15.9;liver: 20.1;urinary bladder: 30.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 4.5;Club cells: 1.0;Ionocytes: 2.0;Paneth cells: 2.5;Proximal enterocytes: 1.3;Squamous epithelial cells: 1.1" "Cancer enriched" "Detected in some" 5 "urothelial cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 64 "RT4: 121.4" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (1.27e-2)" "unprognostic (1.35e-1)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (9.71e-12)" "unprognostic (9.26e-2)" "unprognostic (1.96e-1)" 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 2.8 0.0 0.0 1.9 0.0 6.5 0.0 0.0 0.0 1.8 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 8.8 0.0 0.5 0.0 0.0 0.1 4.3 1.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.4 30.0 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.4 0.2 UGT1A10 UGT1J ENSG00000242515 "UDP glucuronosyltransferase family 1 member A10" Q9HAW8 2 233636454-233773305 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 22.0;intestine: 79.5;stomach 1: 32.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.8;Gastric mucus-secreting cells: 3.6;Intestinal goblet cells: 1.0;Paneth cells: 1.4;Proximal enterocytes: 3.9;Squamous epithelial cells: 4.3" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 143 "RT4: 523.3" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "unprognostic (9.33e-2)" "unprognostic (7.64e-2)" "unprognostic (2.45e-3)" "unprognostic (1.73e-1)" "prognostic unfavorable (4.55e-4)" "unprognostic (1.49e-10)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (3.59e-3)" 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 49.5 79.5 0.1 0.0 14.6 0.0 22.0 0.0 0.0 0.0 0.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 36.5 0.0 0.9 0.0 0.0 0.9 53.1 1.9 0.0 0.0 32.7 1.5 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 1.4 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 523.3 0.0 0.1 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 UGT1A9 "HLUGP4, LUGP4, UGT1AI" ENSG00000241119 "UDP glucuronosyltransferase family 1 member A9" O60656 2 233671898-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 370 "kidney: 458.6;liver: 195.6" "Group enriched" "Detected in some" 11 "Hepatocytes: 7.5;Proximal tubular cells: 6.6" "Group enriched" "Detected in some" 157 "liver cancer: 16.1;renal cancer: 16.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "A549: 1.4;RT4: 1.2" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.46e-2)" "unprognostic (3.56e-1)" "prognostic unfavorable (5.04e-5)" "unprognostic (4.26e-2)" "unprognostic (1.60e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 458.6 195.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A7 UGT1G ENSG00000244122 "UDP glucuronosyltransferase family 1 member A7" Q9HAW7 2 233681938-233773299 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "esophagus: 83.8" "Cell type enriched" "Detected in some" 4 "Squamous epithelial cells: 40.7" "Group enriched" "Detected in some" 10 "cervical cancer: 1.2;head and neck cancer: 2.3;lung cancer: 3.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "SiHa: 112.2" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "unprognostic (6.27e-2)" "unprognostic (1.02e-1)" "unprognostic (7.76e-2)" "unprognostic (1.03e-2)" "unprognostic (1.09e-1)" "unprognostic (7.92e-2)" "unprognostic (1.71e-7)" "unprognostic (2.14e-1)" "unprognostic (4.57e-2)" 0.1 1.3 0.2 0.0 0.2 0.0 0.4 0.5 0.8 1.2 0.4 0.3 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.3 0.2 0.7 4.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 5.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.2 0.4 7.1 1.0 0.0 1.8 0.1 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 112.2 7.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.8 0.3 0.2 0.2 0.5 0.2 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.4 2.3 1.3 4.6 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 2.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.0 40.7 1.7 0.0 0.0 0.0 0.5 8.5 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UGT1A5 UGT1E ENSG00000240224 "UDP glucuronosyltransferase family 1 member A5" P35504 2 233712992-233773299 "Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;intestine: 7.4;liver: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 56: Intestine - Transmembrane transport" "unprognostic (2.18e-3)" "unprognostic (1.36e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.4 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A4 "HUG-BR2, UGT1D" ENSG00000244474 "UDP glucuronosyltransferase family 1 member A4" P22310 2 233718736-233773300 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 391.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 15.1" "Cancer enriched" "Detected in single" 487 "liver cancer: 24.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (9.89e-3)" "unprognostic (6.77e-5)" "unprognostic (2.59e-1)" "unprognostic (3.50e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 391.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A3 UGT1C ENSG00000243135 "UDP glucuronosyltransferase family 1 member A3" P35503 2 233729108-233773299 "Cancer-related genes, Enzymes, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 73.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "liver cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HaCaT: 11.4" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.15e-2)" "unprognostic (9.93e-2)" "unprognostic (2.97e-1)" "unprognostic (4.59e-2)" "unprognostic (1.04e-4)" "unprognostic (8.22e-2)" "unprognostic (2.08e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 73.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 5.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UGT1A1 "GNT1, UGT1, UGT1A" ENSG00000241635 "UDP glucuronosyltransferase family 1 member A1" P22309 2 233760270-233773300 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "intestine: 201.2;liver: 322.4" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 105.0" "Cancer enriched" "Detected in some" 19 "liver cancer: 16.4" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HaCaT: 14.0;OE19: 64.5;RT4: 34.7" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (7.28e-2)" "unprognostic (2.49e-2)" "unprognostic (3.60e-1)" "unprognostic (5.69e-2)" "unprognostic (4.17e-3)" "unprognostic (6.31e-3)" "unprognostic (1.94e-5)" "unprognostic (2.78e-3)" "unprognostic (2.99e-4)" 0.1 0.1 0.6 0.2 0.5 0.5 0.2 1.5 0.8 0.1 0.2 3.0 201.2 0.2 0.4 3.5 0.1 1.0 0.2 0.4 0.8 4.0 322.4 0.2 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.2 2.4 0.9 0.5 0.3 0.1 1.8 79.2 0.1 0.0 0.2 2.4 0.6 0.3 0.1 0.2 0.1 0.3 10.0 0.9 0.6 0.3 1.1 0.2 0.2 0.1 0.1 0.6 0.0 0.0 0.0 0.1 5.4 0.3 0.2 2.5 0.1 0.1 14.0 0.0 0.2 0.0 0.2 0.1 0.1 0.6 1.6 0.0 0.5 0.2 0.2 0.6 0.0 0.0 0.1 0.0 0.3 0.2 0.6 0.0 0.8 0.1 0.3 0.5 64.5 6.5 0.1 0.1 0.6 0.0 34.7 0.2 0.4 2.6 0.4 0.0 0.2 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.2 0.2 0.1 0.7 0.4 0.2 0.9 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.1 1.4 0.3 0.1 0.1 0.1 0.0 0.6 0.5 1.5 0.8 0.4 0.8 0.2 0.2 0.2 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.0 1.8 0.0 0.1 2.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.1 105.0 0.0 0.0 0.0 0.4 0.0 2.4 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.1 6.9 14.6 2.2 1.5 0.0 0.0 0.4 0.1 0.2 0.1 1.5 0.0 0.0 0.1 0.0 0.7 7.3 MROH2A HEATR7B1 ENSG00000185038 "Maestro heat like repeat family member 2A" A6NES4 2 233775679-233833423 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 1.7;thyroid gland: 1.6" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 3.4;Early spermatids: 1.3;Hepatocytes: 1.0;Late spermatids: 1.7;Spermatocytes: 1.5" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RT4: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052107 Uncertain Uncertain Cytosol NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA052107: AB_2681729" "unprognostic (7.00e-2)" "unprognostic (3.37e-3)" "unprognostic (4.77e-1)" "unprognostic (1.65e-2)" "unprognostic (4.03e-1)" "unprognostic (1.71e-1)" "unprognostic (1.87e-1)" "unprognostic (4.41e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" "unprognostic (5.05e-2)" "unprognostic (4.06e-9)" "unprognostic (5.65e-2)" "unprognostic (3.90e-2)" "unprognostic (1.18e-1)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.1 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.4 3.4 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.3 HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.4;lymphoid tissue: 30.4" "Cell type enhanced" "Detected in many" "Early spermatids: 17.4;Erythroid cells: 38.3;Extravillous trophoblasts: 16.1;Granulosa cells: 14.8;Spermatocytes: 37.5;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA008436, HPA027261" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitochondria" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Nucleoli, Nucleoli rim" Mitochondria "HPA008436: AB_1850757, HPA027261: AB_2672184" "unprognostic (5.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.87e-1)" "unprognostic (1.44e-3)" "unprognostic (3.62e-1)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.37e-5)" "prognostic unfavorable (2.46e-4)" "prognostic unfavorable (6.49e-4)" "unprognostic (9.48e-2)" "prognostic unfavorable (7.72e-5)" "unprognostic (7.60e-2)" "unprognostic (0.00e+0)" "unprognostic (7.42e-2)" "unprognostic (5.58e-2)" "unprognostic (1.89e-2)" "unprognostic (5.74e-2)" 0.6 0.6 0.0 5.5 0.1 47.4 1.1 0.1 0.2 0.8 0.1 3.9 4.1 0.9 0.2 5.6 0.3 0.5 0.3 0.1 0.1 0.4 0.8 1.4 12.6 0.1 0.3 0.2 0.2 0.1 0.1 3.0 0.1 0.4 5.2 0.1 1.0 0.1 0.2 3.6 3.8 1.9 0.0 4.1 2.4 11.1 0.3 30.4 0.3 0.0 12.0 1.4 2.0 0.2 54.5 73.6 68.4 32.7 2.6 5.4 42.8 79.5 37.9 55.2 59.9 51.3 57.6 17.1 9.0 31.4 98.0 61.7 54.9 40.9 72.6 40.0 21.6 65.5 61.4 50.9 0.3 54.1 43.2 1.8 1.5 45.1 30.9 15.7 35.5 51.3 56.6 40.8 103.0 55.3 76.4 59.7 58.9 42.2 49.1 58.4 103.0 30.3 28.6 32.3 39.4 24.7 45.8 34.2 31.7 31.0 25.7 42.1 26.0 59.6 64.6 44.3 87.2 38.6 32.7 67.9 35.7 39.3 151.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.4 0.0 1.2 0.4 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.0 2.9 1.3 0.5 1.9 0.0 0.0 0.7 0.5 1.2 0.0 2.1 0.0 0.0 8.2 0.5 5.6 0.0 0.2 17.4 0.3 1.3 1.1 0.0 38.3 0.0 0.0 16.1 2.0 5.1 1.3 0.0 14.8 2.2 0.3 7.1 0.0 0.0 3.5 0.0 3.0 2.9 9.0 0.6 3.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.0 11.4 1.0 0.5 0.1 0.1 0.0 0.0 0.1 1.9 37.5 16.3 8.9 0.9 1.5 2.3 0.3 7.6 0.9 TRPM8 ENSG00000144481 "Transient receptor potential cation channel subfamily M member 8" Q7Z2W7 2 233917373-234019522 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 57 "liver: 31.5;prostate: 80.2" "Group enriched" "Detected in some" 5 "Hepatocytes: 45.2;Prostatic glandular cells: 16.3" "Cancer enriched" "Detected in some" 27 "prostate cancer: 72.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 5.5;RPTEC TERT1: 8.1;SK-MEL-30: 8.9;WM-115: 5.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (4.41e-3)" "unprognostic (7.91e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (4.60e-3)" "prognostic favorable (7.15e-4)" "unprognostic (3.28e-2)" "unprognostic (3.71e-1)" "unprognostic (9.88e-3)" "unprognostic (7.10e-3)" "unprognostic (4.69e-2)" "unprognostic (3.36e-5)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" 0.0 0.2 0.2 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.1 31.5 0.0 0.1 0.1 0.9 0.0 0.0 0.1 0.5 0.0 0.3 80.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.2 0.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.4 0.6 8.1 0.0 0.5 0.3 0.0 0.1 8.9 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 1.2 2.0 0.0 0.7 0.0 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.3 0.3 0.1 0.9 0.3 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 5.5 0.1 0.0 0.7 0.2 0.0 1.1 2.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 2.3 1.2 0.6 0.5 0.0 2.7 0.3 1.7 0.0 0.3 0.0 4.4 0.0 0.1 0.7 45.2 0.3 0.0 0.9 0.0 0.0 0.6 0.8 3.9 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 16.3 0.0 0.0 0.0 0.2 0.0 0.4 0.2 1.3 0.6 0.0 0.1 0.0 0.5 0.0 0.0 4.1 SPP2 SPP24 ENSG00000072080 "Secreted phosphoprotein 2" Q13103 2 234050679-234077134 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4373 "liver: 519.1" "Cell type enriched" "Detected in some" 20 "Hepatocytes: 258.7" "Cancer enriched" "Detected in some" 112 "liver cancer: 65.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Secreted to blood" NA NA 480000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "prognostic favorable (2.33e-6)" "unprognostic (7.02e-3)" "unprognostic (9.62e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 519.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 5.3 0.3 0.6 0.0 0.7 0.0 0.1 5.1 0.0 5.0 258.7 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 ARL4C "ARL7, LAK" ENSG00000188042 "ADP ribosylation factor like GTPase 4C" P56559 2 234493041-234497081 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "dendritic cells: 610.9;Langerhans cells: 474.5;NK-cells: 437.7;T-cells: 349.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 149.4;RPTEC TERT1: 284.8;U-2197: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028927 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA028927: AB_10602387" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-3)" "prognostic unfavorable (2.90e-7)" "unprognostic (8.01e-3)" "unprognostic (3.35e-2)" "unprognostic (9.26e-2)" "unprognostic (2.68e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-2)" "unprognostic (3.17e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.69e-8)" "unprognostic (8.57e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.99e-5)" 15.1 10.6 15.4 31.7 14.6 65.0 17.3 17.8 18.6 11.4 45.3 9.1 6.6 5.8 9.5 23.2 11.9 31.8 5.1 13.1 21.9 12.2 12.8 16.1 55.3 21.9 17.1 2.1 5.5 10.8 7.4 16.5 21.3 10.3 11.2 9.7 21.6 5.4 1.5 24.1 13.2 5.9 12.8 51.0 13.6 1.2 18.5 74.0 3.7 1.7 32.1 25.5 18.0 13.8 32.3 97.4 12.0 1.6 10.4 3.0 31.6 3.2 13.8 3.8 6.6 45.4 60.4 0.1 8.0 7.7 109.0 23.5 12.0 66.4 4.1 30.4 4.2 0.0 0.6 0.6 10.7 0.1 2.8 6.4 42.2 36.6 21.2 149.4 6.4 78.4 0.4 102.4 16.4 4.4 93.7 0.3 12.6 22.5 21.9 0.3 54.1 18.0 284.8 35.2 44.1 8.1 1.1 7.1 4.7 18.2 0.9 1.9 14.8 60.0 23.2 168.2 61.6 51.1 19.7 1.6 101.9 0.1 32.0 79.8 1.2 27.4 86.7 1.6 85.6 18.1 60.0 69.5 10.3 18.3 53.5 59.1 2.2 61.2 0.9 55.2 83.8 30.0 15.4 14.6 17.8 18.6 13.1 21.9 21.9 17.1 21.3 12.8 18.5 13.8 12.3 73.7 15.9 8.8 63.6 124.8 120.7 18.4 145.1 156.6 40.4 64.6 10.9 67.2 27.0 14.7 8.4 30.0 610.9 2.3 0.0 19.6 7.8 73.9 19.2 23.4 1.8 6.1 15.5 5.7 5.4 23.7 19.9 186.3 27.8 1.1 11.0 3.4 31.4 107.7 103.0 2.5 0.0 208.4 474.5 6.5 0.3 182.1 42.7 6.5 41.8 32.2 437.7 6.0 2.5 16.5 0.1 0.0 132.6 60.4 0.1 0.9 4.7 13.1 0.0 7.0 19.3 0.7 1.9 65.4 42.9 14.6 349.8 0.4 1.2 46.6 SH3BP4 ENSG00000130147 "SH3 domain binding protein 4" Q9P0V3 2 234952017-235055714 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 83.5" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.0;plasmacytoid DC: 3.1" "Lineage enhanced" "Detected in single" "dendritic cells: 3.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037533, HPA037534" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" "HPA037533: AB_10672903, HPA037534: AB_2675528" "unprognostic (2.16e-3)" "unprognostic (1.43e-1)" "unprognostic (2.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (5.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.30e-1)" "prognostic favorable (2.07e-6)" "unprognostic (2.86e-2)" "unprognostic (5.08e-2)" "unprognostic (6.91e-2)" "unprognostic (1.17e-2)" 12.4 9.0 17.8 5.7 21.8 1.1 35.3 21.7 15.9 20.8 20.4 13.8 17.2 12.5 14.5 7.7 17.5 19.0 10.2 14.5 16.2 18.3 26.1 13.2 2.2 21.3 21.1 22.5 61.3 5.8 4.0 18.2 20.5 20.3 13.7 2.4 83.5 16.8 9.5 16.6 11.1 13.6 15.8 5.6 25.6 10.2 19.7 4.7 11.1 9.4 3.8 9.4 7.5 28.1 49.3 30.6 77.7 5.8 33.8 22.4 35.2 70.2 66.6 54.6 48.8 23.5 28.8 0.0 19.0 140.4 126.8 26.1 22.6 47.2 64.8 0.2 10.3 0.0 39.5 64.1 55.8 0.0 0.1 43.9 69.9 76.6 41.4 52.4 58.7 0.1 0.4 0.2 81.4 37.8 0.1 0.2 42.5 56.2 16.8 0.0 16.0 9.3 50.0 9.9 47.9 19.3 15.8 101.4 42.7 55.2 11.9 0.2 47.2 59.8 52.2 47.1 45.7 0.0 0.1 0.2 55.6 0.1 89.2 0.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 17.8 21.8 21.7 15.9 14.5 16.2 21.3 21.1 20.5 15.8 19.7 28.1 23.5 3.2 9.1 4.2 1.0 14.8 50.2 15.6 14.2 2.3 37.3 18.0 6.6 18.6 22.5 7.3 6.2 8.7 3.9 6.0 9.8 24.7 3.4 21.4 10.9 22.9 6.6 1.3 0.7 24.8 29.9 11.7 14.8 29.2 1.3 10.0 17.2 26.8 2.1 3.3 1.4 9.1 16.2 1.4 13.1 4.9 8.1 10.9 24.9 20.6 2.6 1.3 0.0 18.1 52.4 39.6 6.3 9.4 0.2 96.9 0.8 1.9 20.7 0.7 0.0 1.9 12.4 0.8 2.8 8.8 11.1 37.1 0.5 5.5 18.0 30.4 AGAP1 "CENTG2, GGAP1, KIAA1099" ENSG00000157985 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 1" Q9UPQ3 2 235494043-236131800 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.9;retina: 54.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 304.0;Cone photoreceptor cells: 329.4;Excitatory neurons: 289.3;Oligodendrocyte precursor cells: 1438.1;Oligodendrocytes: 997.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 1.2" "Cell line enhanced" "Detected in many" "SCLC-21H: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" "unprognostic (1.69e-1)" "unprognostic (2.32e-2)" "unprognostic (3.42e-1)" "unprognostic (5.43e-2)" "unprognostic (1.19e-1)" "unprognostic (4.80e-2)" "prognostic unfavorable (2.60e-5)" "unprognostic (1.36e-1)" "unprognostic (6.91e-2)" "prognostic unfavorable (9.75e-4)" "unprognostic (1.46e-1)" "unprognostic (2.10e-1)" "prognostic favorable (6.52e-5)" "unprognostic (5.56e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.32e-2)" 5.3 4.7 30.7 3.4 34.4 1.9 8.3 7.6 29.6 5.7 0.0 12.5 7.0 5.2 8.9 6.6 6.7 5.6 5.9 34.0 33.0 7.7 2.6 5.6 1.7 44.6 24.1 5.5 6.5 8.9 7.1 6.9 48.2 4.8 11.2 54.7 4.2 5.0 8.4 3.7 8.6 10.5 10.9 1.9 6.7 6.6 30.5 1.5 9.1 9.2 1.9 6.2 3.4 53.9 17.3 13.6 20.9 9.8 15.1 9.7 13.1 8.6 9.1 9.9 7.5 14.0 31.3 0.1 3.6 14.9 37.2 4.3 15.8 20.4 12.3 0.3 8.1 26.4 12.5 10.5 6.0 0.1 17.5 14.1 19.3 20.4 15.9 7.1 6.8 6.1 13.8 1.0 12.6 22.2 0.5 3.0 9.1 14.9 6.2 3.6 10.6 16.8 10.8 20.4 78.9 19.9 7.3 17.1 9.5 11.4 9.8 4.1 6.8 11.8 12.0 9.8 11.7 5.4 0.1 0.8 18.4 0.2 12.7 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 30.7 34.4 7.6 29.6 34.0 33.0 44.6 24.1 48.2 10.9 30.5 53.9 16.0 6.4 15.5 100.6 0.2 4.1 3.7 6.2 5.2 304.0 19.4 11.7 22.9 2.8 8.7 11.0 329.4 9.7 5.5 23.3 3.9 21.4 9.4 24.0 12.0 13.3 16.3 0.4 289.3 15.0 1.5 19.5 4.6 15.8 20.8 12.7 7.9 6.3 1.4 119.5 219.0 17.8 12.2 0.6 3.8 2.9 5.0 2.1 1.8 139.6 1.6 33.3 9.2 1438.1 997.9 19.1 20.7 13.5 0.8 4.9 21.1 14.0 14.4 142.0 26.3 20.4 22.5 4.8 20.7 7.1 4.3 6.6 3.0 7.0 21.8 4.9 GBX2 ENSG00000168505 "Gastrulation brain homeobox 2" P52951 2 236165236-236168386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "brain: 14.3" "Cell type enriched" "Detected in single" 4 "Early spermatids: 2.8" "Group enriched" "Detected in some" 6 "glioma: 1.7;testis cancer: 6.6" "Region enhanced" "Detected in many" "thalamus: 14.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.5;BEWO: 8.3;PC-3: 14.2;TIME: 7.7" "Region enhanced" "Detected in single" "thalamus: 1.3" "Group enriched" "Detected in some" 4 "midbrain: 2.5;pons: 2.7;thalamus: 6.4" HPA067809 Approved Nucleoplasm Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA067809: AB_2685900" "unprognostic (5.30e-2)" "unprognostic (1.15e-1)" "unprognostic (7.09e-2)" "unprognostic (1.59e-1)" "unprognostic (2.91e-2)" "unprognostic (4.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (8.13e-2)" "unprognostic (6.99e-2)" "unprognostic (3.55e-4)" "unprognostic (8.69e-7)" "unprognostic (2.08e-1)" "unprognostic (1.01e-2)" "unprognostic (5.47e-2)" "unprognostic (9.39e-4)" 0.0 0.0 1.5 0.0 1.8 0.0 0.0 2.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.7 0.0 0.0 0.0 0.0 4.9 5.3 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.2 14.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.6 0.9 47.5 1.8 0.0 0.0 8.3 0.7 0.0 1.3 0.0 1.1 0.0 0.0 0.9 0.0 1.4 0.0 0.4 0.1 0.3 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 3.9 0.0 3.4 0.0 0.6 1.2 0.0 0.4 1.2 0.0 14.2 0.0 5.1 0.0 0.4 0.0 0.6 0.3 1.6 0.0 0.5 1.5 0.0 0.0 7.7 0.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.8 2.0 1.2 0.4 2.7 4.9 5.3 3.6 3.0 14.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 ASB18 ENSG00000182177 "Ankyrin repeat and SOCS box containing 18" Q6ZVZ8 2 236194872-236264409 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.8;heart muscle: 7.4;skeletal muscle: 11.3" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 6.5;Excitatory neurons: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA068447 Approved Nucleoli,Mitochondria NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria Nucleoli "HPA068447: AB_2685991" "unprognostic (1.12e-1)" "unprognostic (7.33e-3)" "unprognostic (3.07e-1)" "unprognostic (1.78e-6)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" 0.0 0.0 0.6 0.0 4.8 0.0 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.0 0.6 0.0 0.0 0.0 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 11.3 0.0 0.0 0.0 1.5 0.0 0.0 0.5 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 4.8 1.0 1.0 1.0 0.6 2.3 2.0 1.4 1.5 3.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IQCA1 "DRC11, FLJ22527, IQCA" ENSG00000132321 "IQ motif containing with AAA domain 1" Q86XH1 2 236324147-236507535 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;choroid plexus: 22.7;thyroid gland: 19.2" "Cell type enhanced" "Detected in many" "Astrocytes: 180.9;Endometrial ciliated cells: 54.7;Respiratory ciliated cells: 115.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.3" "Cell line enhanced" "Detected in some" "EFO-21: 3.2;HBEC3-KT: 3.3;HeLa: 3.8;hTERT-RPE1: 6.9;SuSa: 4.4;U-2 OS: 12.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 7.2" HPA057320 Uncertain Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 9: U-2 OS - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA057320: " "unprognostic (1.73e-2)" "unprognostic (6.38e-2)" "unprognostic (3.75e-3)" "unprognostic (1.62e-2)" "unprognostic (6.27e-3)" "unprognostic (1.73e-2)" "unprognostic (3.23e-5)" "unprognostic (1.55e-1)" "unprognostic (7.23e-3)" "unprognostic (1.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.62e-1)" "prognostic favorable (2.54e-4)" "unprognostic (1.19e-3)" "unprognostic (1.67e-3)" "unprognostic (1.91e-3)" "unprognostic (5.30e-2)" 2.2 1.2 23.3 0.4 25.3 0.0 1.8 18.1 46.0 1.3 22.7 0.2 0.1 1.7 5.4 0.7 11.0 1.7 0.5 21.2 21.1 4.6 0.1 2.7 0.4 20.8 27.0 2.4 1.3 1.4 10.3 0.2 19.7 1.5 0.1 2.2 1.2 1.3 0.0 0.2 0.3 0.5 13.9 3.1 0.5 4.5 22.2 2.8 19.2 0.0 0.6 1.7 1.0 16.7 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.2 0.0 0.1 0.3 0.1 0.0 0.0 3.2 0.0 1.0 0.0 0.0 3.3 0.0 0.0 0.1 0.0 3.8 0.0 0.1 0.0 0.0 0.2 1.7 0.0 0.0 6.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 12.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.2 0.3 1.3 0.0 0.4 0.0 0.0 0.0 0.0 23.3 25.3 18.1 46.0 21.2 21.1 20.8 27.0 19.7 13.9 22.2 16.7 2.8 16.0 12.6 180.9 0.4 0.5 7.8 26.9 1.8 26.2 1.7 14.1 1.3 11.5 26.7 3.7 16.7 0.5 0.0 0.0 0.0 10.8 24.0 54.7 5.2 10.4 0.0 0.0 26.0 1.5 5.6 3.3 0.5 9.8 1.3 6.7 2.2 0.0 0.3 0.0 11.6 0.0 16.2 0.0 0.0 14.5 2.1 0.4 0.0 9.4 0.0 0.5 1.0 4.5 2.4 1.2 0.0 6.0 0.3 1.7 0.0 11.7 115.7 2.3 0.0 0.8 2.2 31.0 28.3 0.8 0.3 0.3 0.8 1.9 0.0 3.1 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 COPS8 "COP9, CSN8, MGC1297, SGN8" ENSG00000198612 "COP9 signalosome subunit 8" Q99627 2 237085882-237100474 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 451.5;U-138 MG: 536.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036485 Uncertain Supported Nucleoplasm,Cytosol NA NA 110000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA036485: AB_10670720" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (8.74e-2)" "unprognostic (1.07e-3)" "unprognostic (1.20e-1)" "unprognostic (3.54e-3)" "prognostic unfavorable (4.70e-5)" "unprognostic (1.34e-2)" "unprognostic (8.03e-2)" "unprognostic (2.04e-1)" "unprognostic (6.85e-2)" "unprognostic (2.70e-1)" "unprognostic (2.41e-2)" "unprognostic (7.36e-3)" "unprognostic (2.30e-1)" "unprognostic (1.40e-1)" "unprognostic (8.82e-2)" 51.2 47.8 58.1 36.0 62.8 41.2 42.0 61.2 67.3 42.8 54.9 36.3 17.0 44.1 38.1 26.8 37.4 42.4 83.7 64.5 76.1 51.9 34.4 29.4 32.5 59.4 59.4 48.2 22.6 64.1 37.5 43.7 62.4 34.1 24.7 91.8 27.7 35.9 172.9 30.4 23.8 54.1 62.2 24.1 30.3 47.2 64.0 48.7 37.2 118.1 32.9 52.0 32.5 63.2 58.9 48.6 103.5 51.8 289.5 226.1 69.2 100.7 99.0 100.3 110.7 31.9 57.9 39.9 37.6 110.0 159.5 43.3 102.4 136.1 138.8 94.9 66.2 58.0 57.5 113.8 199.4 76.3 33.3 376.9 153.0 101.2 451.5 124.6 119.4 84.7 81.9 37.4 320.9 55.7 94.7 77.7 91.7 63.0 70.2 71.7 123.3 79.9 124.7 46.4 50.8 87.3 60.3 51.2 155.4 82.4 59.5 61.4 127.4 536.9 91.1 106.1 110.7 71.1 64.0 127.9 167.4 46.0 138.7 59.1 45.2 56.1 57.1 53.3 70.9 68.3 60.4 65.8 55.7 56.9 58.3 60.7 14.1 72.2 58.0 40.2 70.7 70.5 58.1 62.8 61.2 67.3 64.5 76.1 59.4 59.4 62.4 62.2 64.0 63.2 46.8 32.1 24.4 13.1 38.5 75.5 50.0 97.1 39.9 55.2 32.3 26.8 114.2 31.5 44.4 33.1 27.1 61.6 32.5 12.5 142.8 65.1 34.7 45.0 41.2 52.2 21.0 39.6 20.6 40.8 79.3 85.7 23.0 28.7 42.6 38.9 38.9 23.5 61.0 35.3 20.1 16.5 95.6 29.6 59.3 21.1 72.7 24.2 126.3 11.2 44.6 98.2 39.1 15.1 20.6 52.6 16.7 75.6 44.4 44.9 22.6 96.9 55.3 63.0 59.2 44.7 69.8 98.1 116.1 33.6 64.5 44.5 44.5 50.0 21.0 41.8 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 MLPH "exophilin-3, l(1)-3Rk, l1Rk3, ln, Slac-2a" ENSG00000115648 Melanophilin Q9BV36 2 237485428-237555322 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 135.9;salivary gland: 122.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 125.0;Alveolar cells type 2: 389.7;Gastric mucus-secreting cells: 251.8;granulocytes: 187.3;Intestinal goblet cells: 189.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 142.9;MCF7: 255.4;SK-BR-3: 234.5;SK-MEL-30: 182.2;U-87 MG: 236.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA014685 Enhanced NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA014685: AB_1853997" "unprognostic (3.32e-3)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "prognostic favorable (5.14e-6)" "unprognostic (2.26e-4)" "unprognostic (1.36e-2)" "unprognostic (5.44e-2)" "unprognostic (2.66e-1)" "unprognostic (3.74e-3)" "unprognostic (8.16e-2)" "unprognostic (5.73e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (2.34e-1)" "unprognostic (9.37e-2)" "unprognostic (2.66e-2)" "unprognostic (1.60e-3)" 13.2 1.4 0.6 2.4 0.7 0.1 56.9 0.7 1.6 69.3 1.3 20.4 8.8 18.1 8.9 6.4 18.0 31.0 69.2 1.1 0.7 4.3 39.0 62.7 0.6 1.1 1.0 11.8 16.1 9.0 2.1 1.9 0.8 135.9 21.7 0.3 122.0 13.0 6.6 11.6 15.2 2.8 0.6 0.2 98.1 2.5 0.8 0.9 39.9 2.5 1.2 22.1 21.9 0.9 0.3 133.7 0.3 0.3 58.5 39.5 0.4 26.8 31.5 14.7 18.5 1.1 101.1 0.2 0.1 49.6 51.0 0.3 0.1 0.9 13.0 0.1 0.3 0.1 0.1 0.0 23.3 0.1 0.7 48.1 14.7 43.4 56.2 75.6 0.1 0.0 0.1 0.3 142.9 255.4 0.4 0.6 0.4 105.4 77.1 0.5 0.1 0.2 0.5 3.2 1.5 0.2 0.1 234.5 182.2 0.7 61.5 1.7 26.8 80.1 2.3 0.9 38.0 0.2 0.2 0.2 236.0 0.1 63.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.7 1.6 1.1 0.7 1.1 1.0 0.8 0.6 0.8 0.9 12.3 125.0 389.7 0.0 0.8 4.1 17.3 6.0 0.0 0.0 95.6 59.7 63.2 52.9 64.2 12.9 0.0 0.4 0.7 34.9 1.9 12.0 0.2 9.5 10.1 10.1 14.4 0.0 0.2 41.3 0.3 4.5 251.8 17.5 187.3 0.2 1.4 28.8 1.2 0.0 0.1 189.0 32.6 0.8 2.9 0.7 8.4 7.4 30.2 5.6 0.6 0.0 0.0 0.0 0.0 58.1 22.4 3.0 0.8 54.4 9.1 0.6 48.5 0.0 0.0 3.1 3.7 0.3 0.6 1.2 2.4 0.7 6.1 0.4 30.5 38.6 PRLH PRH ENSG00000071677 "Prolactin releasing hormone" P81277 2 237566574-237567175 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 22.8" "Cell type enhanced" "Detected in single" "Endometrial ciliated cells: 1.0" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.7" "Region enhanced" "Detected in many" "medulla oblongata: 22.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.3;MCF7: 1.8;RPMI-8226: 1.4" "Group enriched" "Detected in some" 58 "hypothalamus: 11.3;pons and medulla: 21.5" "Region enriched" "Detected in single" 14 "medulla oblongata: 5.5" HPA014976 Uncertain "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA014976: AB_2732413" "unprognostic (8.28e-4)" "unprognostic (3.22e-2)" "unprognostic (5.42e-2)" 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 1.2 0.0 0.0 0.1 0.0 22.8 0.1 0.0 0.0 0.0 0.2 0.0 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 8.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 1.2 22.8 0.1 0.5 5.0 0.9 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RAB17 ENSG00000124839 "RAB17, member RAS oncogene family" Q9H0T7 2 237574322-237601614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.7;liver: 107.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Distal tubular cells: 137.0;Hepatocytes: 121.7;Proximal enterocytes: 222.5;Proximal tubular cells: 170.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 42.4;Hep G2: 39.9;MCF7: 52.0;SK-BR-3: 48.1;SK-MEL-30: 86.7;T-47d: 34.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA035176 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA035176: AB_10696368" "unprognostic (8.66e-2)" "unprognostic (1.13e-1)" "unprognostic (1.44e-3)" "unprognostic (9.14e-2)" "unprognostic (2.48e-3)" "unprognostic (1.26e-3)" "unprognostic (1.33e-1)" "unprognostic (5.36e-2)" "unprognostic (3.49e-2)" "unprognostic (2.68e-2)" "prognostic favorable (4.14e-4)" "unprognostic (5.87e-2)" "prognostic favorable (3.33e-13)" "unprognostic (1.17e-2)" "unprognostic (1.36e-1)" "unprognostic (3.44e-1)" "prognostic favorable (2.51e-4)" 0.8 1.0 0.9 1.6 0.6 0.4 15.0 0.6 1.3 6.7 25.8 16.4 76.7 2.3 19.4 2.1 11.1 14.7 1.5 2.2 0.7 49.8 107.6 23.1 0.4 0.8 0.7 0.6 38.7 36.9 3.0 13.8 0.7 7.0 15.6 4.2 34.8 15.3 1.4 0.9 73.7 1.0 0.6 0.5 33.5 0.7 0.9 1.0 33.4 0.0 0.8 3.8 0.3 0.7 9.5 0.3 0.0 17.7 0.1 0.2 42.4 0.2 0.1 0.0 0.1 28.7 26.6 0.0 5.6 0.2 0.1 0.4 0.0 12.5 0.2 0.0 0.0 0.0 0.1 39.9 0.0 0.2 0.0 0.0 7.8 0.0 0.9 0.7 0.0 0.1 0.0 0.0 1.0 52.0 0.0 0.6 0.5 28.6 0.1 1.1 0.0 3.4 13.7 25.1 10.5 0.1 0.0 48.1 86.7 9.4 34.8 0.7 0.0 0.2 0.6 0.1 0.1 0.1 1.2 0.0 0.1 2.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.6 1.3 2.2 0.7 0.8 0.7 0.7 0.6 0.9 0.7 1.2 60.9 34.3 0.3 0.5 1.8 3.4 3.3 22.8 1.7 32.2 18.3 1.0 65.8 11.9 46.0 106.3 16.0 0.1 49.6 137.0 40.0 0.0 18.2 1.6 1.8 30.3 0.0 0.8 28.0 3.8 0.7 29.0 22.1 0.0 0.4 2.5 121.7 1.9 0.0 1.5 23.9 24.4 2.2 0.6 0.7 8.7 1.3 5.4 0.0 0.6 0.2 0.0 1.0 0.1 27.9 50.1 3.8 0.1 5.3 222.5 170.2 13.7 0.6 0.0 0.3 0.7 0.0 0.2 6.6 0.6 12.3 1.3 0.7 21.9 6.5 LRRFIP1 "FLAP-1, FLIIAP1, GCF-2, HUFI-1, TRIP" ENSG00000124831 "LRR binding FLII interacting protein 1" Q32MZ4 2 237627587-237813682 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 322.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006979 Approved Supported Cytosol NA NA 580000 "Cluster 52: Eosinophils - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA006979: AB_1079282" "unprognostic (2.07e-1)" "unprognostic (2.99e-2)" "unprognostic (4.09e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.08e-2)" "unprognostic (3.99e-3)" "unprognostic (8.90e-2)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (2.69e-2)" "unprognostic (8.07e-2)" "unprognostic (7.64e-2)" 44.2 21.0 11.3 49.2 9.0 86.8 34.0 3.8 11.0 34.1 23.0 63.2 35.9 64.3 15.7 58.2 32.1 39.4 69.7 11.7 10.8 51.7 48.9 61.7 45.4 7.3 6.9 16.0 21.2 55.1 14.8 41.4 7.0 40.9 40.3 6.4 38.0 31.2 111.0 23.7 35.9 58.8 5.9 45.7 49.6 5.4 9.4 43.5 37.8 50.7 52.6 69.4 43.4 7.3 99.1 50.1 17.5 45.9 25.4 55.6 77.7 67.4 62.3 37.8 37.2 19.2 64.6 8.4 27.4 108.8 81.2 80.9 54.0 100.4 80.2 322.6 34.7 78.0 55.1 54.8 58.5 104.2 71.0 23.9 205.8 88.2 216.0 50.6 59.8 54.0 58.4 77.8 79.5 47.8 60.5 79.5 29.6 73.3 45.1 87.9 125.3 80.1 122.0 141.8 46.3 24.0 33.5 76.2 92.2 37.6 42.9 129.2 99.4 42.4 41.1 49.5 77.0 15.8 14.3 53.2 63.4 102.7 51.0 78.5 104.1 248.4 74.8 97.5 55.1 55.9 89.0 77.3 84.1 60.1 46.1 52.2 326.2 46.9 168.9 73.1 76.7 61.4 11.3 9.0 3.8 11.0 11.7 10.8 7.3 6.9 7.0 5.9 9.4 7.3 236.4 487.2 307.3 35.6 249.6 307.0 391.9 166.0 113.3 46.4 128.6 86.2 160.3 127.2 269.9 172.9 37.5 111.2 347.1 319.5 52.8 229.7 7.9 368.3 88.2 213.0 190.5 62.4 175.9 333.0 359.2 109.1 159.0 426.3 241.0 56.9 122.0 149.1 175.8 21.9 237.5 168.3 79.3 271.2 721.3 7.9 29.8 398.9 167.2 57.1 365.0 25.1 213.1 111.1 12.5 389.6 220.6 23.3 146.6 430.5 152.8 49.5 286.1 6.0 78.9 147.3 182.9 10.1 27.4 179.3 243.1 25.3 288.5 158.3 150.0 588.4 RBM44 FLJ40411 ENSG00000177483 "RNA binding motif protein 44" Q6ZP01 2 237798389-237842808 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 15.7" "Group enriched" "Detected in many" 4 "Spermatocytes: 104.7;Spermatogonia: 59.8" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA003298 Enhanced NA NA "Cluster 34: Basophils - Unknown function" "Cluster 36: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA003298: AB_2284846" "unprognostic (1.29e-1)" "unprognostic (2.66e-1)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "unprognostic (8.47e-3)" "unprognostic (3.15e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (1.83e-2)" "unprognostic (8.12e-2)" "unprognostic (4.10e-2)" "unprognostic (4.57e-2)" "unprognostic (5.01e-5)" "unprognostic (1.90e-1)" "unprognostic (4.27e-2)" "unprognostic (6.85e-3)" "unprognostic (7.89e-3)" 0.3 0.0 0.0 0.1 0.0 0.5 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.1 15.7 0.0 0.0 0.1 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.2 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.1 1.6 0.4 0.8 0.7 0.3 0.6 0.0 0.8 0.3 0.7 1.5 1.5 1.8 0.0 0.1 2.2 0.0 0.0 0.1 16.8 2.0 0.5 2.4 0.0 0.0 2.4 0.2 0.3 1.0 0.0 4.6 0.0 0.3 0.0 0.2 0.3 0.0 3.3 0.0 0.0 0.8 2.3 16.1 2.8 1.5 1.8 1.9 1.4 0.0 1.0 3.0 0.4 0.6 0.0 1.5 1.0 2.0 0.1 0.1 1.8 0.0 6.6 2.6 0.7 104.7 59.8 0.2 0.6 0.0 0.8 0.7 0.0 1.6 RAMP1 ENSG00000132329 "Receptor activity modifying protein 1" O60894 2 237858893-237912106 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 706.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 190.0;Endometrial stromal cells: 546.4;Exocrine glandular cells: 278.2;monocytes: 433.5" "Cancer enhanced" "Detected in all" "prostate cancer: 152.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "NK-cell: 70.1" "Lineage enriched" "Detected in many" 18 "NK-cells: 70.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.4;HDLM-2: 146.0;PC-3: 173.8;SH-SY5Y: 201.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057814 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "HPA057814: AB_2683536" "unprognostic (1.13e-2)" "unprognostic (5.96e-2)" "unprognostic (3.03e-3)" "unprognostic (3.69e-1)" "unprognostic (4.29e-1)" "unprognostic (1.75e-1)" "prognostic favorable (7.61e-4)" "unprognostic (2.54e-1)" "unprognostic (3.49e-1)" "unprognostic (5.45e-3)" "unprognostic (2.32e-1)" "unprognostic (1.43e-1)" "unprognostic (2.46e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.74e-1)" "unprognostic (3.98e-2)" "unprognostic (2.08e-3)" 18.7 29.2 170.9 21.0 171.2 0.9 7.4 168.7 253.4 362.4 153.7 349.6 57.5 706.0 25.0 9.4 256.6 28.5 287.6 176.0 181.8 26.0 82.7 32.5 6.6 198.8 164.5 45.2 225.0 1.4 15.2 8.6 163.0 142.2 6.4 0.8 10.0 54.6 212.3 11.6 73.5 125.4 171.7 12.3 103.4 5.1 183.5 2.9 6.8 68.8 2.9 171.4 75.1 173.2 29.8 0.0 0.5 0.0 12.4 17.9 1.1 2.1 3.6 1.7 1.5 0.0 47.4 0.3 0.4 0.9 0.1 0.2 7.6 0.1 0.2 146.0 4.0 0.1 0.0 1.2 40.6 0.0 0.2 15.6 22.3 0.1 0.3 0.2 0.0 0.0 0.0 0.3 3.7 2.7 0.1 1.3 0.4 0.1 173.8 0.0 1.5 0.8 0.0 0.0 1.5 201.7 3.5 0.0 0.1 1.8 1.3 0.1 0.0 0.8 0.6 0.4 0.5 0.3 0.3 0.0 0.6 0.1 2.7 0.0 0.0 0.0 3.8 0.0 0.0 0.3 0.6 0.1 1.0 0.0 0.5 0.2 0.4 70.1 0.0 0.2 0.0 3.4 170.9 171.2 168.7 253.4 176.0 181.8 198.8 164.5 163.0 171.7 183.5 173.2 1.0 0.0 1.5 64.9 3.1 11.6 13.2 26.9 10.2 2.0 4.4 4.4 190.0 78.6 43.8 11.0 0.0 3.0 44.0 2.1 0.0 62.7 0.2 26.5 546.4 6.2 115.4 4.4 14.2 278.2 5.5 41.7 31.1 11.3 1.3 0.6 30.7 104.0 22.7 1.7 19.2 73.7 10.2 3.1 50.3 0.6 8.4 20.3 64.0 13.1 433.5 6.9 61.8 71.9 11.5 63.5 87.7 11.3 1.9 66.1 96.8 0.2 97.0 2.7 6.6 16.6 78.6 0.3 5.8 2.6 5.8 2.3 7.3 0.5 105.8 28.5 UBE2F NCE2 ENSG00000184182 "Ubiquitin conjugating enzyme E2 F (putative)" Q969M7 2 237966827-238042782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 282.2;monocytes: 215.5;NK-cells: 193.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA037444 Approved Approved Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "HPA037444: AB_10672491" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (3.80e-2)" "unprognostic (6.92e-3)" "unprognostic (3.39e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (3.43e-3)" "unprognostic (6.64e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (1.59e-7)" "unprognostic (2.04e-2)" "unprognostic (6.39e-2)" "unprognostic (3.60e-2)" "unprognostic (2.51e-1)" 26.7 29.7 33.0 25.5 33.7 41.8 22.8 35.9 40.6 27.7 32.5 29.6 24.7 23.1 53.0 43.1 18.8 28.7 56.7 33.4 38.0 28.2 44.2 22.6 32.1 37.5 37.7 12.6 70.5 41.8 21.0 39.9 38.7 25.4 33.7 16.0 25.2 30.3 60.7 18.8 26.9 35.6 35.5 23.7 26.5 26.0 36.1 34.5 35.4 69.1 33.1 40.7 23.5 38.3 42.9 23.9 53.6 55.1 69.2 83.0 74.8 38.9 55.5 43.3 44.4 26.0 26.4 22.0 13.7 88.7 93.7 35.1 62.3 84.9 67.9 33.7 22.7 31.6 28.5 86.6 86.2 13.1 70.1 48.1 137.7 57.9 87.1 40.1 78.1 100.8 94.2 13.7 80.1 64.0 35.1 55.9 59.8 60.9 33.8 41.8 35.0 39.1 66.3 17.8 36.0 53.0 45.2 36.2 77.0 89.4 31.0 52.8 49.7 47.6 41.7 54.9 43.1 17.1 14.3 43.6 57.1 38.4 35.8 112.4 50.0 63.8 66.3 68.2 26.2 26.2 44.8 40.4 45.0 25.4 40.7 41.4 37.3 102.3 78.5 56.4 51.6 63.6 33.0 33.7 35.9 40.6 33.4 38.0 37.5 37.7 38.7 35.5 36.1 38.3 17.6 6.4 18.4 0.0 26.4 32.5 24.1 33.0 11.4 24.2 37.7 24.9 48.1 30.0 21.6 27.6 8.4 84.9 87.3 38.6 56.7 49.7 23.6 15.0 23.9 27.1 41.8 102.5 0.0 79.4 282.2 24.9 15.8 13.8 21.5 13.1 22.1 41.7 152.7 26.9 0.0 58.1 32.6 72.2 105.7 61.3 25.7 67.6 35.6 0.0 215.5 28.3 193.6 0.0 0.0 71.8 31.9 30.9 25.7 46.0 49.7 62.2 23.4 21.7 39.5 14.8 31.4 123.5 79.4 19.0 40.3 65.7 36.2 16.0 35.5 34.6 SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060924-238099413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 39.1" "Group enriched" "Detected in many" 13 "Early spermatids: 90.6;Late spermatids: 156.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "HPA020190: , HPA055760: AB_2682910" "unprognostic (7.39e-3)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (8.65e-5)" "unprognostic (8.96e-2)" "unprognostic (9.85e-3)" "unprognostic (1.14e-3)" "unprognostic (4.24e-2)" "unprognostic (1.59e-2)" "unprognostic (8.38e-2)" "unprognostic (3.98e-3)" "unprognostic (1.03e-2)" "unprognostic (1.02e-3)" "unprognostic (3.73e-1)" "unprognostic (4.37e-2)" "unprognostic (2.50e-3)" "unprognostic (1.98e-1)" 5.1 4.3 7.2 5.3 9.4 5.0 4.9 9.4 9.3 6.8 6.4 7.3 8.5 8.1 5.6 5.9 6.3 3.8 8.1 6.8 8.2 12.9 39.1 4.7 5.7 9.2 8.8 6.3 22.8 6.1 5.0 2.0 9.4 5.9 3.2 4.6 4.4 4.1 6.4 3.5 8.6 3.9 7.3 7.2 5.8 16.8 8.3 5.9 7.2 3.5 4.3 7.8 5.1 10.4 11.1 19.1 11.9 31.1 9.0 6.4 23.2 11.2 5.6 11.3 14.3 11.6 8.0 18.9 3.3 5.9 35.4 16.4 44.1 21.5 10.9 21.2 41.8 21.1 24.0 37.6 16.7 17.6 18.2 7.1 11.6 21.3 22.0 5.1 21.0 26.1 38.0 5.1 11.7 16.9 17.9 33.0 36.4 16.0 15.6 22.0 23.3 18.2 11.3 3.6 13.1 28.9 12.0 19.4 20.6 8.2 6.3 26.5 8.5 16.3 11.8 24.2 23.7 14.2 13.3 9.3 11.3 37.0 14.4 1.1 3.2 4.0 2.6 2.3 2.0 2.6 3.1 4.4 3.3 1.6 2.3 2.6 0.5 2.9 3.5 0.6 3.2 2.8 7.2 9.4 9.4 9.3 6.8 8.2 9.2 8.8 9.4 7.3 8.3 10.4 2.2 0.0 0.0 0.0 4.6 1.7 2.4 1.9 5.7 5.4 1.7 1.9 2.6 1.5 1.2 0.0 8.4 1.4 3.4 1.9 3.9 5.3 90.6 1.7 3.4 2.4 2.4 9.4 0.0 3.7 2.1 1.9 5.1 2.6 0.0 3.5 1.8 3.3 4.0 6.7 0.0 3.3 8.2 0.9 3.2 156.3 3.1 2.1 1.8 0.0 2.7 2.6 2.1 0.0 0.0 3.0 5.0 0.0 4.9 1.9 3.9 2.7 1.9 6.9 0.0 1.9 3.2 6.2 5.6 3.4 1.6 0.7 4.4 2.2 4.8 1.8 ESPNL FLJ42568 ENSG00000144488 "Espin like" Q6ZVH7 2 238100340-238133287 "Predicted intracellular proteins" Hearing Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.0;intestine: 3.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;Cardiomyocytes: 2.5;Granulosa cells: 2.0;Muller glia cells: 1.4;Proximal tubular cells: 3.4;Skeletal myocytes: 1.6;Theca cells: 2.2" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 12 "cerebellum: 5.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.8;Daudi: 2.6;fHDF/TERT166: 2.3;HHSteC: 2.6;THP-1: 1.8;U-87 MG: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA055103 Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA055103: AB_2682694" "unprognostic (8.04e-2)" "unprognostic (1.29e-1)" "unprognostic (2.34e-2)" "unprognostic (1.18e-3)" "unprognostic (1.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.01e-2)" "unprognostic (3.20e-1)" "unprognostic (1.79e-1)" "unprognostic (2.18e-1)" "unprognostic (2.95e-1)" "unprognostic (2.24e-1)" "unprognostic (3.94e-6)" "unprognostic (3.49e-2)" "unprognostic (8.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.67e-2)" 0.4 0.3 0.4 0.1 0.2 0.0 0.4 5.0 0.2 0.8 0.9 0.8 0.3 1.0 0.0 0.2 1.5 0.1 0.7 0.4 0.3 0.3 1.6 0.2 0.5 0.2 0.3 2.2 0.3 0.0 2.1 0.1 0.4 0.6 0.0 0.0 0.0 0.8 0.2 0.2 3.5 0.4 0.0 1.1 0.2 0.4 0.2 0.3 1.0 0.0 0.2 0.6 0.4 0.3 0.0 0.0 0.0 1.8 0.3 0.6 0.3 1.0 0.4 0.8 0.8 0.0 0.0 2.6 1.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.9 2.6 0.0 0.5 0.9 0.0 0.1 0.0 0.0 0.0 0.8 0.8 0.0 1.0 0.0 0.0 1.1 0.1 0.0 0.0 0.8 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.2 0.4 0.3 0.2 0.3 0.4 0.0 0.2 0.3 0.1 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.6 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 2.0 0.0 0.5 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 1.6 0.3 0.0 0.6 0.0 0.0 0.0 0.4 2.2 0.0 0.0 KLHL30 FLJ43374 ENSG00000168427 "Kelch like family member 30" Q0D2K2 2 238138668-238152947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "skeletal muscle: 149.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Skeletal myocytes: 9.8;Smooth muscle cells: 3.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.1;CAPAN-2: 1.6;EFO-21: 1.5;REH: 1.4;RH-30: 4.5;THP-1: 2.3" "Region enriched" "Detected in single" 35 "olfactory bulb: 9.4" "Not detected" "Not detected" HPA062095 Approved "Centriolar satellite" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Centriolar satellite" "HPA062095: AB_2684680" "unprognostic (3.42e-2)" "unprognostic (1.04e-1)" "unprognostic (2.07e-4)" "unprognostic (6.02e-5)" "unprognostic (1.29e-1)" "unprognostic (1.22e-2)" "unprognostic (1.31e-1)" "unprognostic (4.54e-3)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (5.57e-3)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (8.17e-4)" "unprognostic (2.75e-2)" "unprognostic (2.30e-1)" "unprognostic (2.06e-1)" 3.8 0.1 0.2 0.1 0.2 0.0 1.4 0.5 0.2 2.2 0.2 1.0 0.2 1.2 0.0 1.0 1.3 0.5 14.3 0.1 0.4 1.0 0.1 0.9 0.0 0.9 0.8 0.4 0.1 0.0 0.1 0.3 0.3 1.0 0.1 0.1 1.0 0.8 149.1 0.8 0.7 0.7 0.1 0.2 0.5 0.1 0.2 0.0 0.6 15.2 0.0 1.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 1.6 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.1 0.1 0.0 0.0 1.4 4.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.2 0.1 0.4 0.9 0.8 0.3 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 9.8 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ERFE "C1QTNF15, CTRP15, FAM132B, FLJ37034" ENSG00000178752 Erythroferrone Q4G0M1 2 238158970-238168900 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 11.8;skeletal muscle: 14.9;testis: 12.8;thyroid gland: 24.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 6.3;Club cells: 2.5;Collecting duct cells: 1.8;Distal tubular cells: 3.9;Glandular and luminal cells: 1.8;granulocytes: 5.1;Respiratory ciliated cells: 2.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 20.3;RH-30: 25.6" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted to blood" NA NA 277000 "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (1.66e-1)" "unprognostic (9.14e-2)" "unprognostic (3.64e-4)" "prognostic unfavorable (3.75e-4)" "unprognostic (2.84e-1)" "unprognostic (9.61e-4)" "unprognostic (4.68e-3)" "unprognostic (3.16e-3)" "unprognostic (9.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.31e-4)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.46e-4)" "unprognostic (4.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.33e-2)" 0.7 0.1 3.3 2.2 4.0 4.1 0.4 4.6 6.7 0.7 2.2 0.5 0.6 0.4 0.0 0.4 0.5 0.3 0.9 3.9 2.4 11.8 0.5 0.9 0.1 2.4 2.5 0.1 0.4 0.0 0.1 1.2 2.5 0.7 0.2 0.0 0.3 0.4 14.9 0.1 0.9 0.4 2.2 0.8 0.5 12.8 2.7 0.1 24.9 0.6 0.1 2.3 0.3 2.7 3.1 0.8 1.4 3.0 0.2 4.9 0.3 2.0 3.2 4.9 8.7 0.2 7.7 0.0 5.4 0.5 10.0 0.3 13.7 0.7 4.5 0.0 15.2 0.0 0.3 0.2 1.8 0.1 1.1 10.5 1.5 20.3 14.3 0.6 0.1 6.5 4.6 0.0 13.6 3.8 0.0 8.9 2.1 0.9 1.5 17.3 25.6 0.8 10.7 0.1 0.4 7.7 3.1 0.5 9.7 2.5 0.4 15.5 1.0 8.2 7.1 3.2 10.7 0.0 0.0 1.1 12.2 4.5 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 4.6 6.7 3.9 2.4 2.4 2.5 2.5 2.2 2.7 2.7 0.2 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.5 1.8 0.0 0.2 0.7 0.0 3.9 0.1 0.0 1.2 0.2 0.5 0.0 0.0 0.0 0.0 0.2 1.2 0.0 1.8 5.1 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 2.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 ILKAP "DKFZP434J2031, FLJ10181, PPM1O" ENSG00000132323 "ILK associated serine/threonine phosphatase" Q9H0C8 2 238170402-238203708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004752, HPA056099" Uncertain Supported Nucleoplasm NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004752: AB_1851753, HPA056099: AB_2797255" "unprognostic (1.50e-1)" "unprognostic (1.62e-1)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" "unprognostic (9.75e-2)" "prognostic unfavorable (1.04e-4)" "unprognostic (1.60e-1)" "unprognostic (3.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.37e-3)" "unprognostic (7.03e-2)" "prognostic unfavorable (9.89e-6)" "unprognostic (6.24e-2)" "unprognostic (6.63e-2)" "unprognostic (2.63e-2)" "unprognostic (1.20e-1)" 20.5 17.4 24.3 15.1 25.6 29.0 19.5 26.5 26.9 26.2 22.3 30.8 14.6 25.1 15.3 23.2 23.4 8.7 24.2 23.8 24.9 26.0 26.2 18.6 20.5 24.9 24.2 24.5 20.6 13.1 26.5 12.9 24.1 25.2 12.9 13.0 17.3 14.5 41.4 22.4 23.3 16.1 23.9 25.9 21.4 23.1 24.6 17.9 23.9 18.3 18.1 26.6 21.8 27.4 40.5 25.6 36.9 36.3 28.1 18.6 37.9 41.5 27.9 40.9 35.4 23.7 20.9 25.8 10.5 30.1 48.8 33.8 48.1 34.4 41.2 46.6 49.8 66.7 26.0 52.7 43.3 43.7 50.3 19.6 23.3 43.6 43.6 20.2 31.1 34.0 52.4 16.1 35.4 48.1 43.4 58.0 34.8 37.4 25.9 52.6 75.6 23.7 30.4 18.8 54.1 26.7 28.2 29.6 68.9 27.9 23.3 43.7 28.9 39.7 36.7 53.5 45.1 28.6 31.4 46.7 32.5 47.3 34.3 43.4 19.8 27.1 28.2 25.6 25.4 24.7 24.9 26.4 27.7 24.0 28.8 22.9 7.3 24.8 21.4 20.9 30.7 23.0 24.3 25.6 26.5 26.9 23.8 24.9 24.9 24.2 24.1 23.9 24.6 27.4 27.7 12.8 22.0 43.8 35.4 27.0 29.1 30.8 25.0 28.9 19.4 21.6 23.1 17.2 19.6 25.8 29.2 41.2 51.5 22.4 43.0 27.9 8.1 17.1 20.6 21.5 19.1 64.2 37.7 28.5 43.7 26.7 29.0 16.1 33.7 43.5 22.1 19.2 34.4 38.7 33.2 24.0 16.2 17.0 22.0 12.6 28.3 24.0 30.2 25.3 34.0 25.1 57.7 36.7 72.2 24.8 16.2 29.3 33.6 29.7 24.1 33.4 19.3 28.6 32.9 29.2 47.4 54.4 70.8 29.2 28.7 40.4 36.6 23.0 27.4 23.5 HES6 bHLHb41 ENSG00000144485 "Hes family bHLH transcription factor 6" Q96HZ4 2 238238267-238240662 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.2;pituitary gland: 62.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 86.0;Enteroendocrine cells: 109.9;Erythroid cells: 120.0;Intestinal goblet cells: 176.0;Ionocytes: 93.6" "Cancer enhanced" "Detected in all" "glioma: 62.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "eosinophil: 5.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.1" "Cell line enhanced" "Detected in many" "NB-4: 196.8;SCLC-21H: 123.5;SK-MEL-30: 192.4;THP-1: 85.1;U-937: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073997 Approved "Nuclear bodies,Cytosol" NA No "Cluster 52: Eosinophils - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 24: NB-4 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Cytosol "HPA073997: " "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.56e-1)" "unprognostic (2.40e-3)" "unprognostic (7.46e-3)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.79e-4)" "prognostic favorable (9.18e-5)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.41e-2)" "unprognostic (4.35e-1)" "unprognostic (6.30e-2)" "unprognostic (5.13e-2)" "unprognostic (8.50e-2)" "unprognostic (6.66e-2)" "unprognostic (3.49e-2)" 3.4 10.2 44.8 2.8 53.1 12.5 2.6 55.1 57.6 13.8 32.4 22.3 18.4 16.9 0.5 3.0 14.0 1.6 4.7 43.8 37.8 10.0 8.3 5.5 3.1 49.6 43.3 2.6 23.5 4.1 62.6 1.1 44.8 3.9 9.0 1.0 5.1 1.0 25.8 2.6 19.8 2.7 56.2 9.1 11.1 25.5 43.9 3.6 5.1 1.6 2.2 4.6 2.8 58.2 4.9 5.6 23.5 26.9 1.6 0.8 15.1 1.7 1.8 2.3 3.5 4.8 3.0 0.3 3.9 0.4 9.8 3.1 24.1 1.8 0.7 11.5 30.4 5.9 4.5 50.7 3.8 42.7 33.0 2.3 14.6 3.4 4.7 1.3 1.5 25.1 53.4 0.5 1.5 12.3 6.3 196.8 38.5 4.8 4.3 28.1 62.5 11.7 3.1 2.3 123.5 54.6 7.7 10.7 192.4 2.8 9.4 85.1 1.9 2.3 4.9 13.2 14.7 11.6 2.1 8.9 8.2 100.2 4.2 0.1 0.1 5.1 0.5 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.4 0.1 44.8 53.1 55.1 57.6 43.8 37.8 49.6 43.3 44.8 56.2 43.9 58.2 3.3 0.0 1.1 63.0 5.7 3.3 6.4 3.0 1.8 9.2 8.8 5.2 6.5 1.5 4.7 3.7 22.9 2.2 30.5 37.1 7.9 9.2 32.2 86.0 7.8 3.8 109.9 120.0 9.6 31.8 3.9 3.5 13.7 6.7 0.0 39.0 2.2 5.2 5.5 3.3 10.3 176.0 93.6 4.8 5.8 9.3 1.5 7.4 35.6 8.4 8.3 6.2 23.7 17.6 19.6 14.9 22.2 1.5 7.1 5.2 13.1 4.9 9.5 4.9 0.0 26.9 12.5 35.3 36.5 2.9 2.0 0.3 9.4 30.0 41.8 2.2 PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myocytes: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 50: Non-specific - Ribosome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Cytosol "HPA053136: , HPA060510: AB_2684298" "unprognostic (1.96e-2)" "unprognostic (4.41e-2)" "unprognostic (1.88e-2)" "unprognostic (9.28e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.29e-4)" "unprognostic (2.47e-2)" "unprognostic (2.17e-2)" "unprognostic (3.59e-3)" "unprognostic (3.59e-2)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (6.81e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (2.58e-1)" "unprognostic (5.22e-2)" 12.2 3.3 4.7 5.0 5.2 8.4 14.2 7.2 5.8 11.9 2.4 7.6 5.1 10.2 5.7 13.6 7.9 12.3 5.7 5.7 5.1 3.9 12.4 7.1 4.7 5.2 5.7 7.8 14.4 4.2 9.0 2.9 4.4 9.3 6.2 5.1 14.1 8.9 11.4 17.0 8.0 4.9 5.4 4.8 13.4 11.8 4.7 4.1 8.8 7.6 6.2 8.7 8.2 4.7 1.6 11.7 2.4 4.2 0.1 1.2 8.2 1.1 4.1 1.5 1.4 1.8 5.8 10.3 1.2 2.7 1.5 8.6 2.4 3.5 2.2 2.9 1.7 9.1 6.2 8.2 2.0 13.8 9.2 1.6 8.3 1.8 6.1 1.5 0.8 4.2 4.5 6.3 1.3 7.7 6.9 15.2 3.5 7.6 2.3 16.5 5.5 3.3 1.5 3.3 9.7 1.2 2.9 6.3 1.8 0.7 5.9 8.5 2.1 3.6 4.2 2.8 4.1 7.1 1.8 12.3 6.7 5.9 4.5 2.1 1.2 0.3 1.0 2.2 1.6 1.5 1.6 1.2 1.4 1.5 1.5 1.6 1.0 1.2 2.1 1.8 1.2 0.3 4.7 5.2 7.2 5.8 5.7 5.1 5.2 5.7 4.4 5.4 4.7 4.7 24.9 16.0 30.1 18.6 9.9 73.9 61.7 21.3 38.1 20.6 67.8 33.8 5.7 31.5 46.9 27.6 2.1 9.2 27.0 22.5 7.9 7.5 9.6 69.7 30.1 15.6 24.6 6.9 20.9 10.4 6.3 39.8 52.5 86.1 9.5 3.3 11.4 35.8 3.9 11.8 13.9 35.1 18.3 10.1 25.3 4.7 11.1 12.4 24.9 5.6 5.3 13.5 2.1 9.0 7.2 7.6 35.3 18.4 10.9 15.0 10.9 5.5 44.2 7.8 6.6 110.1 32.2 31.3 17.0 38.4 85.4 13.0 13.6 3.7 36.9 33.9 TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 75.3;Endometrial ciliated cells: 150.3;Late spermatids: 75.1;Respiratory ciliated cells: 105.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037857, HPA037858" Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 49: Ciliated cells - Cilium organization" "HPA037857: AB_2675706, HPA037858: AB_10671724" "unprognostic (1.25e-1)" "unprognostic (9.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.87e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.80e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (9.04e-2)" "unprognostic (6.38e-3)" "unprognostic (7.44e-2)" "unprognostic (4.78e-3)" "unprognostic (7.48e-3)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.07e-1)" 7.1 5.0 7.9 4.2 7.7 2.0 6.7 7.1 9.3 7.1 10.5 10.2 5.2 8.4 12.3 6.5 19.3 5.7 5.3 7.4 8.6 6.9 5.6 6.7 4.7 9.9 10.0 7.2 5.4 12.2 5.9 4.9 9.0 7.1 6.0 6.7 6.4 8.1 11.3 5.6 4.9 7.4 9.4 4.9 5.9 14.2 8.5 4.0 10.7 7.5 5.3 7.0 6.2 7.3 8.6 10.4 9.4 11.4 9.2 11.4 6.9 6.9 10.4 8.9 8.3 3.7 6.6 0.2 3.6 9.9 10.3 8.5 10.5 7.9 13.7 5.2 10.7 2.2 9.2 12.7 9.7 10.4 5.8 8.8 12.3 11.3 9.1 8.3 9.1 7.6 10.5 1.9 9.6 10.8 8.3 5.7 10.5 6.8 5.4 13.0 17.1 3.4 12.1 4.0 12.8 6.9 11.7 9.0 9.0 5.7 7.6 7.8 10.4 10.8 8.4 11.0 9.1 4.9 2.8 3.3 10.6 3.7 7.3 0.2 0.2 0.1 0.3 0.1 0.6 0.3 0.3 0.4 0.1 0.2 0.3 0.3 0.3 2.0 1.5 0.4 0.0 0.2 7.9 7.7 7.1 9.3 7.4 8.6 9.9 10.0 9.0 9.4 8.5 7.3 10.9 32.1 18.1 20.5 5.0 7.9 7.8 5.2 9.6 20.3 15.6 11.0 14.6 2.8 21.7 1.8 37.5 7.1 7.4 10.5 0.0 8.1 75.3 150.3 25.2 10.4 10.7 6.1 37.9 9.1 6.0 11.6 9.2 24.5 6.3 16.0 8.2 16.0 4.5 47.1 36.9 9.9 8.2 2.5 6.0 75.1 11.1 4.9 3.6 15.0 3.2 14.5 4.1 16.1 18.1 8.4 7.1 17.0 4.2 7.0 7.8 8.2 105.3 37.8 6.6 17.9 12.4 48.1 44.1 9.1 8.0 3.7 5.1 18.1 11.4 5.9 ASB1 ASB-1 ENSG00000065802 "Ankyrin repeat and SOCS box containing 1" Q9Y576 2 238426742-238452250 "Predicted intracellular proteins" "Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003508 Uncertain Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA003508: AB_1845065" "unprognostic (1.02e-1)" "unprognostic (5.30e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (4.89e-5)" "unprognostic (4.04e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.49e-2)" "unprognostic (5.81e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.56e-4)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.19e-1)" 6.6 5.5 19.1 7.3 18.8 2.9 5.3 14.6 18.1 8.9 9.7 10.1 3.9 10.7 3.7 5.0 8.6 5.3 16.2 17.0 18.6 6.2 6.4 6.4 8.0 18.1 20.0 10.2 5.9 8.4 7.6 3.2 19.5 7.5 4.7 5.5 5.4 7.9 21.1 5.7 8.3 8.1 18.9 7.8 8.0 10.7 19.3 6.7 5.8 23.3 8.5 8.1 6.5 17.1 11.1 15.7 21.2 17.0 13.3 14.0 17.1 29.9 19.8 17.7 19.8 7.7 7.7 9.6 4.0 28.2 39.3 12.0 21.1 47.7 27.7 24.3 17.2 12.1 15.2 19.3 31.1 16.8 15.5 15.0 21.7 51.7 69.7 27.8 7.7 16.7 25.9 6.3 32.9 7.6 9.2 17.8 22.6 9.7 13.2 13.3 43.1 6.4 12.9 15.1 17.1 23.2 9.4 6.9 15.7 12.7 5.2 17.9 16.6 31.8 20.6 25.1 59.9 22.8 15.2 16.5 50.2 5.3 16.2 0.0 0.5 1.0 4.2 0.7 2.2 4.3 3.0 4.1 0.6 2.1 2.5 3.0 0.2 2.1 0.4 2.8 4.1 1.3 19.1 18.8 14.6 18.1 17.0 18.6 18.1 20.0 19.5 18.9 19.3 17.1 2.3 9.6 3.7 7.8 12.2 7.9 27.5 16.4 7.4 10.0 7.4 7.1 45.3 15.7 11.3 9.2 4.2 12.3 12.8 5.2 1.9 15.8 35.2 9.8 8.1 4.0 12.7 19.1 6.1 21.0 28.6 15.0 14.8 4.6 15.9 7.6 5.0 12.5 23.7 10.1 6.1 6.6 10.2 9.5 4.3 19.5 7.8 10.4 7.2 3.7 12.3 9.8 11.3 6.6 8.5 30.4 16.3 14.7 18.5 20.1 8.4 11.3 18.4 6.5 26.3 10.6 16.0 52.1 37.4 7.2 6.8 5.7 13.9 9.9 7.1 15.4 TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 95.4;Fibroblasts: 58.9;Leydig cells: 48.1;Peritubular cells: 39.1;Theca cells: 23.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.6" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.0;ASC TERT1: 50.5;BJ: 69.3;BJ hTERT+: 212.4;fHDF/TERT166: 97.4;U-2197: 81.3" "Low region specificity" "Detected in single" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Nucleoli "HPA062870: AB_2684888" "unprognostic (1.62e-2)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.81e-2)" "unprognostic (2.53e-4)" "unprognostic (1.83e-2)" "unprognostic (4.06e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-2)" "unprognostic (2.33e-1)" "unprognostic (2.24e-1)" "unprognostic (1.17e-1)" "unprognostic (2.40e-9)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (1.98e-2)" "unprognostic (4.48e-2)" 59.7 4.0 0.3 1.4 0.3 0.4 43.3 0.3 0.5 83.0 0.6 22.9 0.3 31.3 0.7 10.1 30.4 1.7 10.8 0.4 0.3 1.8 0.7 9.3 0.3 0.4 0.8 39.9 1.8 0.1 8.3 3.1 0.4 25.7 1.1 0.0 7.9 3.7 1.8 33.5 8.9 2.9 0.4 2.3 10.3 1.9 0.3 0.1 8.2 1.0 0.4 21.3 54.2 0.5 0.1 4.5 0.4 0.0 80.0 50.5 0.1 69.3 212.4 31.0 46.4 0.0 0.0 0.0 2.1 97.4 2.5 0.5 0.7 5.4 22.5 0.0 7.3 0.0 4.0 0.2 13.7 0.0 1.6 11.8 2.9 15.0 12.5 3.7 4.2 0.0 0.0 0.0 4.2 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.1 0.0 0.7 0.0 0.9 11.8 1.2 2.2 81.3 0.8 0.0 0.0 0.0 0.3 2.1 4.3 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.4 0.3 0.4 0.8 0.4 0.4 0.3 0.5 2.5 0.0 2.6 0.0 0.1 2.0 16.0 0.0 7.4 0.0 0.5 0.4 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.4 3.6 95.4 1.3 0.0 0.0 4.4 0.0 1.9 58.9 0.0 2.1 1.3 0.5 2.9 0.1 2.2 0.0 0.2 0.0 0.0 0.0 3.6 1.2 48.1 0.8 1.8 12.2 0.4 0.0 8.2 0.5 0.1 0.1 0.0 39.1 0.0 20.5 0.0 0.0 0.0 0.0 0.0 1.1 9.6 0.5 3.3 0.2 1.7 1.6 1.6 23.2 0.0 3.7 HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Autism spectrum disorder, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.2" "Group enriched" "Detected in many" 4 "Astrocytes: 62.0;Early spermatids: 69.9;Excitatory neurons: 118.1;Inhibitory neurons: 84.9;Late spermatids: 59.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 85.5;Oligodendrocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 32.0;neutrophil: 47.7" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.7" "Cell line enhanced" "Detected in many" "JURKAT: 49.1;MOLT-4: 48.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: AB_2680501, HPA071448: " "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.39e-3)" "unprognostic (3.06e-4)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (6.33e-4)" "prognostic favorable (1.13e-4)" "unprognostic (1.40e-1)" "unprognostic (4.82e-3)" "unprognostic (2.40e-1)" "unprognostic (3.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.04e-2)" 4.4 6.3 9.3 5.0 12.0 17.0 3.8 0.6 13.4 7.5 0.1 29.0 2.7 9.1 2.5 8.0 6.7 7.1 5.2 9.0 6.5 3.7 2.4 3.9 3.5 9.9 6.1 7.5 3.7 2.7 6.5 1.5 11.2 5.6 3.4 2.4 3.3 5.9 58.2 5.9 7.2 6.2 2.3 5.6 7.2 9.2 6.7 9.7 4.2 35.6 2.5 10.0 4.5 10.1 3.2 5.8 4.1 6.1 4.5 3.9 5.9 3.0 2.3 2.3 1.7 2.9 7.5 2.0 1.9 3.4 3.6 3.4 4.0 2.0 1.4 12.8 1.8 3.1 5.1 5.8 3.8 5.5 4.6 4.4 2.6 4.6 3.3 2.3 2.4 49.1 3.7 4.5 2.7 4.7 48.1 10.7 4.0 6.0 2.8 7.6 7.2 4.0 5.3 4.4 4.6 6.4 5.3 2.5 16.2 2.6 1.0 17.9 1.9 5.0 0.4 6.8 4.6 3.3 3.2 3.1 6.9 6.9 7.4 32.0 10.2 2.3 1.0 3.3 1.2 0.2 1.1 1.0 1.0 0.1 0.5 0.5 47.7 3.2 1.7 0.6 1.7 1.1 9.3 12.0 0.6 13.4 9.0 6.5 9.9 6.1 11.2 2.3 6.7 10.1 8.6 3.2 7.4 62.0 5.2 7.9 2.9 3.0 8.6 12.2 6.2 4.8 13.3 7.2 2.9 11.0 2.1 1.5 12.8 4.1 0.0 2.8 69.9 7.0 15.1 7.1 6.0 6.1 118.1 2.2 1.7 14.0 7.7 7.4 2.5 6.6 11.7 6.7 3.2 16.8 84.9 5.2 2.0 17.2 10.0 59.0 11.8 10.3 5.4 38.4 14.9 8.6 15.5 85.5 124.0 1.9 1.6 12.4 7.0 6.4 5.0 1.6 2.6 7.1 0.0 18.7 6.5 2.8 3.3 11.1 9.7 1.4 12.2 4.9 6.4 2.7 NDUFA10 CI-42k ENSG00000130414 "NADH:ubiquinone oxidoreductase subunit A10" O95299 2 239892450-240025743 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 332.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059529, HPA067045, CAB070846" Approved Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB070846: AB_11152346, HPA059529: AB_2684051, HPA067045: AB_2732756" "unprognostic (2.12e-2)" "unprognostic (8.94e-3)" "unprognostic (8.73e-2)" "unprognostic (2.02e-2)" "unprognostic (8.96e-2)" "unprognostic (2.53e-1)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (5.71e-2)" "unprognostic (2.47e-2)" "unprognostic (1.05e-1)" "prognostic favorable (2.09e-7)" "unprognostic (1.16e-1)" "unprognostic (4.96e-2)" "unprognostic (1.98e-1)" "unprognostic (2.95e-1)" 55.4 91.1 36.3 29.6 40.2 50.3 50.3 39.8 51.2 41.0 38.9 83.2 81.6 37.8 28.3 74.6 43.6 31.2 184.8 41.7 36.0 94.2 103.6 35.4 32.3 41.9 39.4 45.4 58.5 99.3 38.5 37.9 41.3 33.1 84.3 31.2 55.9 33.1 206.4 72.4 64.3 39.8 34.0 37.7 71.7 35.3 37.7 45.3 38.8 332.0 49.7 47.3 49.2 39.4 74.4 65.5 46.3 81.5 54.8 95.4 75.5 49.0 70.9 71.3 77.8 72.8 82.8 51.0 31.8 64.2 60.8 96.2 109.8 103.1 92.6 59.7 90.9 72.9 65.6 174.6 72.4 96.9 58.6 95.5 80.3 68.5 85.0 66.6 96.6 74.6 102.0 34.8 81.8 124.8 95.6 110.5 56.3 114.4 81.0 93.2 114.4 81.2 108.7 152.1 70.5 54.6 55.3 131.8 108.9 33.3 121.2 97.4 69.9 52.7 60.7 70.7 75.8 77.3 24.6 79.2 60.3 80.9 72.8 30.2 106.3 47.1 72.9 115.8 93.8 95.4 70.7 77.5 147.9 77.0 68.2 69.4 26.7 97.6 103.3 49.7 92.7 104.6 36.3 40.2 39.8 51.2 41.7 36.0 41.9 39.4 41.3 34.0 37.7 39.4 66.8 76.9 74.1 31.6 63.5 104.9 96.5 193.5 60.3 80.8 88.4 89.5 354.8 87.2 114.0 77.3 62.6 216.4 58.1 137.3 311.0 112.5 47.5 66.8 83.2 67.4 92.9 57.6 83.1 78.5 124.0 71.7 62.2 76.6 65.9 103.7 66.4 139.1 125.2 50.5 68.5 152.3 103.7 90.5 82.0 85.3 50.1 65.2 112.1 27.2 107.8 72.2 53.5 37.7 71.4 77.7 125.5 49.2 56.7 62.1 182.7 303.0 77.7 110.4 65.7 74.6 77.3 84.2 73.4 107.2 118.9 218.1 63.0 185.3 234.2 110.0 OR6B2 OR6B2P ENSG00000182083 "Olfactory receptor family 6 subfamily B member 2" Q6IFH4 2 240028965-240030456 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6B3 "OR6B3P, OR6B3Q" ENSG00000178586 "Olfactory receptor family 6 subfamily B member 3" Q8NGW1 2 240045077-240047027 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "retina: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COPS9 "CSNAP, MYEOV2" ENSG00000172428 "COP9 signalosome subunit 9" Q8WXC6 2 240126563-240136807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 340.8;Breast myoepithelial cells: 395.6;Distal tubular cells: 498.9;Exocrine glandular cells: 383.2;Pancreatic endocrine cells: 347.0;Proximal tubular cells: 720.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044845 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "HPA044845: AB_10962975" "unprognostic (6.05e-3)" "unprognostic (1.44e-1)" "unprognostic (7.22e-2)" "unprognostic (1.04e-1)" "unprognostic (1.04e-1)" "unprognostic (3.72e-2)" "unprognostic (1.72e-3)" "unprognostic (5.64e-2)" "unprognostic (1.79e-2)" "unprognostic (1.26e-1)" "unprognostic (1.25e-3)" "unprognostic (9.02e-2)" "unprognostic (3.02e-1)" "unprognostic (3.71e-1)" "unprognostic (2.26e-2)" "unprognostic (3.03e-1)" "unprognostic (4.37e-2)" 141.9 129.3 373.7 62.2 373.1 80.5 139.6 386.7 485.1 118.8 367.8 164.4 73.5 97.0 142.5 167.4 93.3 59.3 245.9 386.8 372.6 176.8 93.3 92.1 88.4 373.9 376.2 105.7 183.9 72.3 168.3 50.2 375.8 129.9 52.1 50.3 124.6 69.2 282.2 142.7 99.4 59.3 376.9 113.7 149.6 105.2 384.0 74.9 119.2 131.2 58.0 115.3 125.4 396.2 151.7 200.3 154.5 162.4 209.0 169.6 142.0 213.7 147.0 136.5 173.9 146.2 131.7 41.4 62.5 196.0 218.1 118.9 138.4 197.5 94.0 177.6 510.6 125.0 182.8 458.8 166.1 126.7 112.4 201.1 159.9 102.0 126.3 126.1 203.2 207.8 147.3 87.0 201.8 324.3 204.2 391.0 235.5 188.5 433.3 158.3 207.2 129.3 172.4 256.1 178.7 178.8 112.1 150.7 243.1 118.5 139.0 242.2 165.7 179.5 203.1 231.3 206.9 177.4 166.2 220.1 223.8 148.6 180.9 514.1 298.1 415.1 292.3 315.9 293.1 322.9 298.6 301.0 287.2 237.6 260.5 294.1 106.3 259.4 330.2 364.2 386.0 415.1 373.7 373.1 386.7 485.1 386.8 372.6 373.9 376.2 375.8 376.9 384.0 396.2 187.9 128.2 121.1 0.0 41.2 0.0 0.0 0.0 0.0 0.0 340.8 395.6 0.0 0.0 55.7 275.8 0.0 175.1 117.0 0.0 498.9 220.7 0.0 182.6 190.7 75.6 0.0 0.0 0.0 383.2 193.7 82.8 0.0 193.1 61.8 174.9 0.0 0.0 322.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 110.4 0.0 0.0 145.3 0.0 0.0 0.0 0.0 347.0 0.0 0.0 18.6 0.0 0.0 720.0 67.1 0.0 0.0 0.0 93.1 0.0 0.0 0.0 0.0 132.4 69.8 129.2 0.0 0.0 OTOS OTOSP ENSG00000178602 Otospiralin Q8NHW6 2 240139026-240144562 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 103.1;thyroid gland: 43.8" "Cell type enhanced" "Detected in single" "Astrocytes: 1.3" "Cancer enriched" "Detected in some" 4 "thyroid cancer: 28.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "hippocampal formation: 1.6" "Low region specificity" "Detected in many" "Secreted in other tissues" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "unprognostic (8.52e-2)" "unprognostic (1.73e-1)" "unprognostic (9.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.72e-1)" "unprognostic (3.27e-3)" 0.0 0.0 10.9 0.0 11.0 0.0 0.1 11.3 11.5 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 14.2 0.3 0.2 0.0 0.0 10.5 11.7 0.0 0.0 0.0 103.1 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 12.7 0.0 43.8 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 11.0 11.3 11.5 11.7 14.2 10.5 11.7 11.2 9.7 12.7 12.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 ANKMY1 "FLJ20499, ZMYND13" ENSG00000144504 "Ankyrin repeat and MYND domain containing 1" Q9P2S6 2 240479422-240569209 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 67.9" "Cell type enhanced" "Detected in many" "Early spermatids: 187.5;Late spermatids: 213.1;Respiratory ciliated cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA026620, HPA048869" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA026620: AB_1844834, HPA048869: " "unprognostic (2.89e-3)" "unprognostic (1.03e-1)" "unprognostic (3.83e-2)" "unprognostic (3.22e-3)" "unprognostic (3.46e-1)" "unprognostic (3.97e-5)" "unprognostic (8.32e-2)" "unprognostic (1.19e-1)" "unprognostic (4.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.36e-2)" "unprognostic (2.59e-5)" "unprognostic (2.01e-1)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "prognostic favorable (3.20e-4)" 4.9 4.4 6.4 5.7 7.6 12.5 6.3 6.0 7.3 7.5 6.1 6.0 6.5 5.4 8.7 5.8 24.6 4.7 3.4 5.4 4.9 5.0 6.2 6.9 9.0 8.1 12.3 7.4 8.6 6.2 4.5 3.9 8.0 6.6 5.5 3.8 5.1 5.2 3.5 8.2 7.2 3.0 8.0 8.2 9.6 67.9 7.1 7.1 6.5 2.1 6.7 5.7 6.4 11.1 7.0 15.2 3.2 6.0 2.9 4.1 13.4 3.3 5.0 2.7 3.6 4.9 14.2 7.0 0.6 3.7 4.1 7.6 6.2 7.8 3.2 12.9 5.2 13.9 8.6 13.0 2.4 7.8 12.8 6.6 18.7 2.5 17.7 8.2 2.8 11.0 13.2 8.8 4.6 6.7 7.2 12.8 2.7 12.1 9.0 20.1 9.8 11.1 4.1 15.0 7.5 5.6 2.7 7.2 10.0 3.9 6.2 11.9 3.6 10.0 3.3 4.0 5.9 20.0 5.5 7.0 5.7 11.8 7.9 0.0 2.1 4.5 4.6 1.8 2.7 2.8 2.8 2.9 2.7 4.1 4.1 3.0 0.9 1.3 2.3 1.8 0.9 2.4 6.4 7.6 6.0 7.3 5.4 4.9 8.1 12.3 8.0 8.0 7.1 11.1 3.0 0.0 8.1 23.8 7.2 0.9 1.8 5.3 13.1 3.5 4.3 3.7 2.2 1.5 10.1 3.7 4.2 3.0 8.1 4.8 1.9 2.7 187.5 40.8 3.6 3.5 4.2 6.5 17.0 4.3 1.7 2.8 16.8 4.5 5.7 4.8 2.9 6.4 2.7 3.3 25.4 4.5 6.1 7.6 2.0 213.1 4.1 6.7 0.0 38.4 5.5 2.6 7.2 21.1 42.9 3.2 2.2 3.0 3.4 2.8 5.7 2.9 62.6 4.0 0.0 2.2 3.5 28.8 8.9 5.0 2.3 2.9 8.6 2.9 4.7 2.0 DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240565256 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 39.7;Spermatocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 8.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.9" "Cell line enhanced" "Detected in many" "U-266/70: 8.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: AB_10961145" "unprognostic (1.88e-2)" "unprognostic (9.29e-2)" "unprognostic (4.86e-2)" "unprognostic (2.32e-1)" "unprognostic (1.65e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (7.56e-3)" "unprognostic (4.13e-3)" "unprognostic (3.71e-2)" "prognostic favorable (1.84e-4)" "unprognostic (9.85e-2)" "unprognostic (1.80e-3)" "unprognostic (6.99e-2)" "unprognostic (2.52e-1)" "unprognostic (2.59e-1)" "unprognostic (2.10e-3)" 1.5 2.4 1.6 1.3 1.7 5.4 1.7 3.0 1.8 2.2 0.5 2.5 1.1 2.1 1.7 3.1 2.6 0.8 3.4 1.3 1.7 3.2 3.2 2.2 1.9 1.7 1.2 2.2 3.0 0.9 3.9 0.6 1.4 3.5 1.0 1.2 2.8 0.8 9.8 2.0 3.6 0.6 1.1 4.7 2.7 6.2 1.5 1.1 3.5 4.0 1.5 2.3 2.2 2.0 1.0 0.8 1.1 1.4 0.7 0.4 1.3 1.0 0.6 0.8 0.5 0.5 2.4 1.7 0.6 0.6 1.3 3.1 0.9 0.3 0.7 2.2 4.0 2.1 2.2 1.3 0.5 1.6 3.7 1.0 0.9 0.6 0.6 1.6 0.4 2.3 1.6 1.9 0.7 1.1 1.7 2.5 0.9 1.4 0.9 2.3 2.4 2.1 0.6 1.6 2.8 1.5 0.9 1.1 1.3 0.7 1.2 2.2 1.0 1.9 1.6 1.3 1.0 8.2 2.1 2.8 1.2 1.0 1.5 8.9 1.1 0.5 1.2 0.7 1.4 1.0 1.2 1.3 0.6 1.8 1.4 1.2 1.9 1.5 0.7 1.9 0.9 0.9 1.6 1.7 3.0 1.8 1.3 1.7 1.7 1.2 1.4 1.1 1.5 2.0 5.7 0.0 4.5 1.3 11.4 3.7 7.7 4.7 6.2 6.7 12.3 10.0 13.8 10.0 3.8 12.9 4.2 7.8 18.4 11.0 15.6 5.1 35.2 11.2 5.5 4.1 8.4 8.8 3.8 5.8 4.8 4.3 14.8 10.2 7.0 6.2 3.3 8.6 11.5 8.4 4.9 9.8 6.1 10.0 6.1 39.7 3.1 13.6 7.2 1.9 10.5 9.9 23.7 2.5 3.6 4.4 10.4 1.5 16.8 8.0 15.7 15.6 11.7 6.8 6.6 4.1 7.2 45.8 18.7 10.7 5.4 7.0 14.9 7.6 11.2 8.7 RNPEPL1 ENSG00000142327 "Arginyl aminopeptidase like 1" Q9HAU8 2 240565804-240581372 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036772, HPA036773" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA036772: AB_10670848, HPA036773: " "unprognostic (3.92e-2)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.39e-1)" "unprognostic (5.24e-3)" "prognostic favorable (7.43e-4)" "prognostic unfavorable (5.06e-4)" "unprognostic (3.72e-3)" "unprognostic (9.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" "unprognostic (1.98e-2)" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (5.31e-2)" "unprognostic (9.86e-2)" 40.3 31.4 29.1 14.1 29.6 21.7 32.0 29.0 38.7 15.6 27.0 39.6 20.2 16.8 5.6 52.4 17.0 12.1 79.4 27.9 27.8 42.7 50.6 35.9 23.8 31.5 30.0 12.0 64.2 10.9 9.1 10.6 30.3 34.7 9.5 0.8 28.9 13.1 63.7 35.3 39.8 9.4 31.0 56.4 48.4 9.9 31.4 15.9 19.2 17.1 12.1 34.1 23.2 31.1 13.7 22.4 4.9 13.2 17.6 18.1 16.6 8.6 21.1 9.5 11.6 6.3 39.3 3.9 4.3 21.8 13.3 14.6 5.5 16.1 0.9 23.9 7.7 9.0 7.3 37.2 44.1 5.9 15.5 21.6 25.5 4.9 9.6 15.1 32.8 15.2 6.8 25.7 6.5 19.3 7.5 22.4 6.5 26.5 9.0 15.5 7.4 33.3 39.3 18.5 4.6 9.8 5.8 19.7 39.9 5.6 13.9 26.8 22.7 10.2 10.4 14.4 10.0 24.1 3.9 4.8 20.9 16.6 15.7 9.2 11.2 30.5 14.8 9.9 12.7 8.2 11.3 13.4 8.2 8.7 6.4 9.5 20.0 10.7 10.1 9.5 14.7 7.9 29.1 29.6 29.0 38.7 27.9 27.8 31.5 30.0 30.3 31.0 31.4 31.1 27.9 22.4 25.7 10.4 27.8 7.8 15.0 8.4 2.8 6.4 18.8 9.1 35.6 24.3 12.9 12.9 0.0 7.1 80.4 138.9 17.6 24.6 3.1 12.1 11.0 22.7 26.4 22.3 9.5 49.6 6.8 12.3 104.5 27.4 34.2 31.8 30.0 42.2 43.8 3.3 8.6 58.7 8.2 74.3 21.0 5.9 8.7 47.1 23.2 9.4 52.0 15.9 79.3 5.5 10.3 65.0 70.0 13.5 20.5 20.2 77.1 35.6 7.2 6.9 13.1 14.8 16.4 1.3 8.2 13.0 9.2 5.1 47.9 17.4 60.5 23.0 CAPN10 ENSG00000142330 "Calpain 10" Q9HC96 2 240586734-240617705 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 48.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004170, HPA056098" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Cytosol "HPA004170: AB_1078381, HPA056098: AB_2683037" "unprognostic (1.05e-1)" "unprognostic (1.13e-2)" "unprognostic (9.29e-3)" "unprognostic (6.09e-2)" "unprognostic (5.44e-3)" "prognostic favorable (8.47e-5)" "prognostic unfavorable (4.78e-6)" "unprognostic (7.48e-3)" "unprognostic (7.94e-2)" "unprognostic (1.31e-2)" "prognostic favorable (7.94e-5)" "unprognostic (1.46e-1)" "unprognostic (1.11e-2)" "unprognostic (1.19e-1)" "unprognostic (6.88e-2)" "unprognostic (5.76e-2)" "unprognostic (5.58e-3)" 10.0 18.6 16.8 6.8 16.2 7.9 9.6 21.0 25.0 11.8 16.5 12.7 13.1 10.7 3.7 14.5 13.7 6.1 24.6 17.9 14.0 23.8 14.7 12.2 10.6 15.6 15.8 13.3 12.6 5.3 18.1 4.5 15.4 14.9 7.1 10.6 10.2 5.3 5.8 12.1 14.0 2.8 12.6 29.8 15.8 17.0 16.7 6.4 13.2 2.8 5.4 11.1 10.0 16.8 8.0 11.2 11.2 9.5 4.5 3.6 19.7 9.9 4.1 6.5 5.9 8.7 18.7 5.9 3.5 3.6 8.9 12.7 3.0 6.6 3.3 23.0 19.8 10.9 20.4 16.0 7.1 7.1 15.3 2.6 4.8 6.7 2.7 6.7 5.2 16.8 12.5 7.3 2.8 7.1 16.2 27.5 17.4 9.5 8.1 15.5 8.1 13.1 9.9 9.8 28.1 22.0 6.3 9.3 13.8 3.5 4.8 9.3 8.6 11.0 9.7 9.5 11.8 16.3 4.2 10.7 10.4 12.8 11.0 1.5 0.9 1.8 1.0 0.6 0.3 1.0 0.6 1.1 0.4 1.1 0.7 0.9 4.1 3.0 0.6 1.2 1.3 0.4 16.8 16.2 21.0 25.0 17.9 14.0 15.6 15.8 15.4 12.6 16.7 16.8 8.9 3.2 6.0 19.6 7.5 4.6 7.2 3.8 6.2 14.9 6.2 5.3 9.5 12.8 4.8 9.2 14.6 5.4 14.2 7.2 7.9 13.0 1.9 14.7 5.7 7.0 11.3 1.7 9.5 9.1 5.2 5.3 4.6 13.8 22.9 11.3 7.5 3.0 6.7 48.8 9.0 6.3 8.2 5.3 1.7 2.6 9.0 7.8 1.8 7.5 7.7 13.4 8.2 7.5 7.2 13.8 4.6 9.4 7.4 10.1 9.9 6.2 9.4 18.6 0.0 5.6 7.6 12.6 7.7 3.7 5.3 5.5 11.3 9.0 6.4 6.9 GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240631259 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 82.8;granulocytes: 38.1;Intestinal goblet cells: 32.2;Langerhans cells: 35.7;Paneth cells: 38.6;Proximal enterocytes: 99.3;Undifferentiated cells: 31.1" "Group enriched" "Detected in many" 4 "colorectal cancer: 20.7;pancreatic cancer: 6.9;stomach cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 36.3;eosinophil: 40.1;intermediate monocyte: 51.7;myeloid DC: 32.5;non-classical monocyte: 14.5" "Group enriched" "Detected in many" 16 "dendritic cells: 32.5;granulocytes: 40.1;monocytes: 51.7" "Cell line enhanced" "Detected in some" "CACO-2: 20.7;CAPAN-2: 51.2;HDLM-2: 17.6;Hep G2: 33.6;HMC-1: 31.5;NB-4: 16.4;OE19: 38.7;U-937: 18.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.99e-2)" "unprognostic (3.94e-3)" "unprognostic (2.71e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.98e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (7.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-3)" 2.1 0.8 5.5 4.3 4.8 4.5 2.4 4.4 5.8 4.7 2.9 28.3 41.0 3.8 1.2 2.5 7.3 5.9 3.3 5.4 4.6 5.4 1.6 3.4 1.7 5.5 4.6 5.4 1.8 0.2 6.6 0.5 5.6 4.5 16.6 2.0 1.6 1.0 7.0 2.6 38.2 1.9 4.4 10.3 15.8 5.4 5.4 1.8 3.0 0.3 1.0 2.9 2.7 4.6 0.1 0.5 0.3 1.1 0.9 0.0 0.4 0.1 0.3 0.1 0.3 20.7 51.2 0.3 0.2 0.2 0.7 0.5 0.0 0.0 0.1 17.6 0.7 8.7 0.5 33.6 0.4 0.4 31.5 0.2 0.1 0.6 0.3 0.4 0.1 1.3 0.3 2.9 0.0 0.7 0.4 16.4 0.8 38.7 0.2 1.9 0.1 0.5 0.2 0.2 2.0 0.8 0.0 0.1 0.4 0.5 0.2 5.9 0.7 0.2 0.2 1.4 0.1 3.5 1.6 0.2 0.1 18.2 0.4 0.1 36.3 40.1 1.5 51.7 2.6 0.0 0.8 0.8 32.5 0.1 0.5 1.2 0.4 0.8 14.5 0.6 0.3 13.6 5.5 4.8 4.4 5.8 5.4 4.6 5.5 4.6 5.6 4.4 5.4 4.6 0.6 0.0 4.4 7.8 1.6 2.0 0.1 0.2 0.0 1.4 0.4 0.4 1.2 2.8 0.3 1.8 0.0 0.1 5.1 82.8 0.0 0.9 0.1 3.1 0.6 0.4 6.7 0.0 1.9 3.3 0.0 0.3 25.0 3.1 38.1 0.8 0.4 0.3 10.7 1.7 2.1 32.2 0.0 8.5 35.7 0.0 0.3 22.3 0.0 1.9 9.7 0.2 1.0 0.5 1.5 14.1 38.6 1.2 1.2 0.0 99.3 3.7 0.9 2.5 0.0 0.2 0.9 1.2 0.6 0.1 1.1 0.3 8.0 0.1 31.1 0.3 AQP12B INSSA3 ENSG00000185176 "Aquaporin 12B" A6NM10 2 240676418-240682906 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 334 "pancreas: 209.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042216 Supported NA NA "Cluster 25: Pancreas - Digestion" "Cluster 45: Enterocytes - Digestion" "HPA042216: AB_2677905" "unprognostic (1.30e-1)" "unprognostic (2.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.41e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 209.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.6 0.0 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 AQP12A AQP12 ENSG00000184945 "Aquaporin 12A" Q8IXF9 2 240691851-240698483 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 332 "pancreas: 129.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 1.5;Paneth cells: 1.2;Proximal enterocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042216 Supported NA NA "Cluster 25: Pancreas - Digestion" "Cluster 45: Enterocytes - Digestion" "HPA042216: AB_2677905" "unprognostic (9.82e-2)" "unprognostic (1.63e-2)" "unprognostic (9.48e-2)" "unprognostic (2.14e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 129.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KIF1A "ATSV, C2orf20, SPG30, UNC104" ENSG00000130294 "Kinesin family member 1A" Q12756 2 240713761-240824293 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 115.0;pancreas: 34.1;pituitary gland: 42.1;retina: 58.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 393.8;Cone photoreceptor cells: 419.1;Horizontal cells: 536.7;Muller glia cells: 116.4;Rod photoreceptor cells: 176.8" "Cancer enhanced" "Detected in many" "glioma: 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 62.5;HAP1: 146.0;SCLC-21H: 276.0;SH-SY5Y: 52.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005442 Approved "Centriolar satellite,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Centriolar satellite, Cytosol" "HPA005442: AB_1079210" "unprognostic (1.19e-1)" "unprognostic (2.17e-3)" "unprognostic (7.31e-2)" "prognostic unfavorable (4.97e-4)" "unprognostic (1.65e-1)" "unprognostic (4.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (3.09e-2)" "unprognostic (2.06e-2)" "unprognostic (2.60e-1)" "unprognostic (2.54e-1)" "unprognostic (3.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-3)" "unprognostic (3.90e-2)" 0.2 12.4 54.0 1.1 55.6 0.0 0.1 22.4 113.6 0.1 0.0 2.2 0.7 0.3 0.8 0.0 0.2 0.0 13.7 71.8 25.0 0.2 0.4 0.3 0.0 115.0 47.4 0.7 34.1 0.4 42.1 0.0 107.7 5.4 0.5 58.4 0.2 0.2 0.2 1.0 0.8 0.3 10.2 0.4 2.6 11.2 53.9 0.4 0.9 0.1 0.0 0.1 0.6 99.6 0.0 0.2 1.8 62.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 3.5 0.4 1.4 0.6 146.0 0.0 0.0 8.4 10.5 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.3 0.0 2.5 0.3 0.0 8.8 0.0 0.0 0.0 0.6 1.2 0.0 0.0 276.0 52.0 0.0 0.8 0.0 0.4 0.4 0.0 2.0 0.0 1.3 0.4 0.0 0.2 0.1 0.0 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.0 55.6 22.4 113.6 71.8 25.0 115.0 47.4 107.7 10.2 53.9 99.6 0.0 0.0 0.0 50.9 0.0 0.9 0.1 0.0 0.0 393.8 0.1 0.3 16.8 0.0 0.0 0.0 419.1 0.0 0.0 0.1 0.0 0.5 2.2 1.1 0.2 1.2 34.2 0.0 57.6 25.1 0.0 2.9 4.1 5.0 0.0 1.5 0.0 0.4 0.1 536.7 72.4 0.8 8.2 0.0 0.4 4.1 0.9 0.1 17.8 9.4 0.0 116.4 0.0 18.1 50.3 14.6 0.0 0.4 0.0 10.4 0.0 0.3 0.0 176.8 0.0 0.0 1.0 46.2 20.5 0.0 0.0 0.0 0.0 3.8 0.1 0.5 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 MAB21L4 "C2orf54, FLJ22671" ENSG00000172478 "Mab-21 like 4" Q08AI8 2 240886048-240896889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 262.6;vagina: 80.4" "Cell type enriched" "Detected in single" 7 "Cytotrophoblasts: 2.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "CACO-2: 45.9;HaCaT: 34.3;SK-BR-3: 117.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA052722 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Golgi apparatus" "HPA052722: " "unprognostic (5.86e-3)" "unprognostic (4.17e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-2)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (1.70e-1)" "unprognostic (1.89e-2)" "unprognostic (2.83e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (6.46e-2)" "unprognostic (1.55e-1)" "unprognostic (8.26e-2)" "unprognostic (2.05e-1)" 0.2 0.1 0.3 1.0 0.5 0.0 1.8 0.5 1.3 36.0 0.0 2.9 11.5 0.2 0.1 262.6 0.9 0.5 0.1 0.8 0.0 13.3 13.0 10.0 0.3 0.3 0.0 0.1 1.2 0.0 0.2 0.8 0.5 1.5 2.5 0.3 29.2 0.2 0.3 60.8 4.9 0.1 0.0 0.2 5.8 0.2 0.2 1.1 0.1 0.0 23.5 2.0 80.4 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 45.9 2.7 0.3 0.3 0.0 0.0 34.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.0 5.7 0.1 0.1 0.2 7.3 0.0 0.1 0.0 11.4 0.3 5.9 2.3 0.0 0.0 117.0 0.0 0.2 0.9 0.7 0.0 0.0 1.2 0.1 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.5 0.5 1.3 0.8 0.0 0.3 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CROCC2 ENSG00000226321 "Ciliary rootlet coiled-coil, rootletin family member 2" H7BZ55 2 240906330-240993311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.7;choroid plexus: 23.6;fallopian tube: 7.0" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.7;Endometrial ciliated cells: 43.6;Respiratory ciliated cells: 13.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 1.5" "Region enhanced" "Detected in many" "midbrain: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 1.0;RPMI-8226: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048678 Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA048678: AB_2680491" "unprognostic (4.33e-1)" "unprognostic (2.90e-1)" "unprognostic (2.24e-2)" "unprognostic (1.68e-3)" "unprognostic (7.92e-2)" "unprognostic (1.75e-4)" "unprognostic (2.84e-3)" "unprognostic (3.10e-2)" "unprognostic (8.28e-2)" "unprognostic (3.45e-2)" "unprognostic (6.56e-3)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (1.55e-1)" "unprognostic (6.05e-2)" "unprognostic (9.90e-3)" "unprognostic (7.19e-2)" 0.0 0.0 0.6 0.1 0.4 0.0 0.0 0.2 0.1 1.2 23.6 0.0 0.2 0.1 0.0 0.0 7.0 0.0 0.0 1.9 0.8 0.1 0.2 1.5 0.6 3.0 6.7 0.1 0.0 0.0 0.4 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.6 2.3 0.1 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.6 0.4 0.2 0.1 1.9 0.8 3.0 6.7 2.5 1.6 1.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.6 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.1 1.1 0.1 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 1.2 0.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 SNED1 "FLJ00133, Snep, SST3" ENSG00000162804 "Sushi, nidogen and EGF like domains 1" Q8TER0 2 240998618-241095568 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 95.0;Excitatory neurons: 86.0;Leydig cells: 95.1;Microglial cells: 77.8;Peritubular cells: 71.1;Skeletal myocytes: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "ASC TERT1: 410.4;HSkMC: 211.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036414, HPA036415" Uncertain "Secreted to blood" NA NA 27000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA036414: AB_10960852, HPA036415: AB_10964128" "unprognostic (1.41e-1)" "unprognostic (3.92e-2)" "unprognostic (1.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.57e-3)" "unprognostic (4.62e-2)" "unprognostic (7.77e-4)" "unprognostic (3.49e-2)" "unprognostic (4.96e-1)" "unprognostic (7.85e-3)" "unprognostic (3.42e-2)" "unprognostic (2.06e-2)" "unprognostic (2.80e-2)" "unprognostic (1.16e-1)" "unprognostic (3.72e-1)" "unprognostic (5.51e-3)" "unprognostic (4.95e-3)" 23.8 9.3 4.2 6.4 8.5 1.2 15.8 14.1 6.9 34.1 32.4 7.3 4.5 18.0 11.8 6.1 21.6 18.7 11.1 10.7 11.7 7.1 8.0 13.3 4.7 8.3 6.4 21.9 7.3 3.1 7.2 1.9 4.8 12.5 3.4 2.5 14.6 7.5 19.8 12.1 10.4 6.3 0.6 14.1 5.7 9.3 2.2 3.3 30.2 9.1 2.9 11.5 10.7 5.9 0.1 0.6 0.4 4.8 61.1 410.4 0.3 2.4 1.5 0.5 0.2 0.2 0.2 0.1 1.0 4.4 0.5 0.2 0.4 0.0 0.3 2.7 1.0 0.2 4.5 0.4 2.6 0.2 0.5 211.6 0.1 0.5 0.3 28.4 9.5 0.2 0.1 2.7 11.5 2.4 1.6 0.2 0.7 0.1 0.3 0.2 8.1 0.1 5.6 0.5 0.8 0.3 1.9 8.3 4.2 0.6 1.8 0.8 23.7 8.7 0.6 50.9 1.5 0.8 0.4 1.5 11.7 0.1 2.6 0.0 0.0 0.0 0.0 0.3 0.3 1.9 0.4 0.2 0.0 0.6 0.2 0.2 0.0 0.0 0.7 0.0 0.4 0.0 4.2 8.5 14.1 6.9 10.7 11.7 8.3 6.4 4.8 0.6 2.2 5.9 8.0 6.4 11.0 95.0 8.4 3.6 0.9 0.4 2.8 2.8 1.1 1.8 2.4 1.5 8.5 5.5 0.0 0.1 0.3 0.3 0.0 1.2 1.3 10.6 16.8 10.9 2.4 3.2 86.0 1.2 0.1 22.1 2.6 10.7 0.0 5.0 22.9 5.8 0.2 1.7 32.5 0.2 0.0 2.9 5.9 5.9 95.1 2.7 1.8 77.8 0.6 7.4 0.0 11.6 7.0 0.7 0.1 71.1 0.9 3.0 0.0 0.5 4.2 1.2 26.3 53.7 4.9 0.6 1.5 0.7 2.6 0.4 1.8 36.4 0.5 0.6 MTERF4 "MGC61716, MTERFD2" ENSG00000122085 "Mitochondrial transcription termination factor 4" Q7Z6M4 2 241072169-241102332 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027097 Uncertain Supported Mitochondria,Cytosol Yes No "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Mitochondria, Cytosol" "HPA027097: AB_10603879" "unprognostic (4.58e-2)" "unprognostic (3.66e-1)" "unprognostic (2.82e-1)" "unprognostic (5.95e-2)" "unprognostic (1.50e-1)" "unprognostic (6.70e-2)" "unprognostic (1.17e-3)" "unprognostic (2.99e-2)" "unprognostic (2.68e-2)" "unprognostic (1.20e-2)" "prognostic favorable (3.48e-4)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-1)" 15.4 15.7 8.7 22.7 10.6 23.8 21.8 17.5 14.5 21.8 6.7 18.2 16.1 25.3 16.1 19.4 19.0 14.2 17.3 9.1 10.3 15.7 20.4 17.0 38.8 9.1 8.3 27.9 17.5 16.2 15.3 14.2 9.6 33.8 19.9 29.4 19.8 18.1 54.4 17.6 22.0 20.1 6.4 22.0 18.3 10.2 9.1 25.1 34.7 41.8 30.8 14.8 16.0 12.7 17.2 14.9 29.7 16.4 38.2 17.5 22.1 27.4 31.5 25.8 36.0 10.5 23.2 24.7 10.0 31.0 30.8 17.6 41.0 38.5 33.8 35.4 28.9 32.2 30.5 46.5 25.5 40.2 23.3 29.0 37.8 30.2 35.6 32.8 30.2 32.4 29.4 10.5 31.9 24.0 28.2 26.4 33.7 35.5 25.8 27.7 33.1 14.1 24.8 31.5 26.2 22.9 20.3 26.8 20.7 19.5 19.6 19.4 39.3 23.4 23.0 27.3 25.7 28.0 7.9 61.2 19.8 24.1 21.4 8.3 10.8 24.9 18.6 10.5 22.7 32.3 29.1 26.8 12.3 31.8 46.0 36.7 3.4 18.1 8.7 9.1 32.5 22.1 8.7 10.6 17.5 14.5 9.1 10.3 9.1 8.3 9.6 6.4 9.1 12.7 20.7 12.8 27.7 40.8 45.6 0.0 20.3 0.0 15.9 0.0 19.8 23.9 19.8 27.1 13.0 20.2 0.0 30.2 34.1 12.1 41.1 24.1 49.2 11.7 19.1 22.4 10.9 22.9 31.2 24.6 28.2 18.6 14.3 12.0 11.4 37.9 20.0 30.6 24.8 0.0 28.8 20.7 0.0 24.5 0.0 61.0 23.3 17.0 0.0 25.3 31.6 0.0 42.2 33.2 39.8 23.7 20.7 26.4 44.8 22.0 43.4 51.4 17.5 0.0 39.5 22.7 18.4 59.0 34.3 23.4 0.0 23.7 37.0 42.9 17.2 17.1 PASK "KIAA0135, PASKIN, STK37" ENSG00000115687 "PAS domain containing serine/threonine kinase" Q96RG2 2 241106099-241150264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 24.5;Theca cells: 26.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 19.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA016450, HPA021079" Uncertain Supported Cytosol NA Yes "Cluster 21: B-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA016450: AB_1854992, HPA021079: AB_1854993" "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.84e-1)" "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (8.99e-6)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-3)" "unprognostic (1.58e-2)" "unprognostic (1.02e-2)" "unprognostic (6.35e-2)" "unprognostic (7.12e-2)" "unprognostic (1.52e-3)" "unprognostic (1.68e-1)" "unprognostic (6.44e-2)" "unprognostic (4.38e-3)" 1.6 1.1 3.7 7.1 19.8 8.8 2.1 1.0 5.3 2.5 3.1 2.4 3.4 2.1 3.9 3.3 6.1 2.0 1.1 2.7 1.7 3.7 1.4 3.2 13.7 1.9 1.9 1.9 3.6 2.4 4.6 1.0 1.8 10.0 2.3 11.9 2.9 1.4 0.8 4.1 4.5 1.2 0.3 4.1 3.0 16.1 3.2 22.9 5.1 0.2 7.8 2.1 2.2 5.2 7.4 9.9 12.9 16.7 1.1 1.9 17.4 7.0 2.2 6.3 8.8 8.1 7.4 3.8 1.4 1.5 13.8 17.9 15.1 6.1 4.6 15.6 13.8 10.6 19.1 14.4 0.8 14.7 16.0 0.9 4.7 6.5 1.9 2.6 4.6 16.2 14.0 5.2 4.5 8.0 17.5 15.4 14.6 8.8 5.9 27.5 13.3 4.7 2.5 16.0 23.1 7.0 3.9 8.0 3.2 6.8 6.7 10.5 6.1 8.8 7.7 11.1 9.6 6.8 7.4 18.1 5.4 10.9 8.2 4.4 0.6 0.5 1.0 0.4 0.9 4.5 3.9 3.5 0.8 3.9 2.3 2.6 0.8 1.9 0.7 0.4 4.1 2.2 3.7 19.8 1.0 5.3 2.7 1.7 1.9 1.9 1.8 0.3 3.2 5.2 2.3 3.2 7.9 2.6 8.5 2.7 1.2 1.6 2.2 2.6 3.5 4.3 3.1 2.8 1.9 3.7 4.2 0.9 2.2 3.1 0.0 1.5 14.9 13.9 1.6 8.5 0.0 13.3 12.5 2.0 1.7 2.7 3.6 4.4 3.8 11.7 17.5 1.5 2.0 1.7 6.1 3.5 0.0 4.7 2.0 3.5 5.9 2.1 12.4 3.7 2.7 2.1 7.2 0.5 2.6 0.9 1.0 24.5 4.7 1.7 1.9 1.4 12.3 18.7 0.0 2.1 2.1 16.1 12.7 2.6 1.4 0.3 19.1 26.5 3.9 0.9 PPP1R7 sds22 ENSG00000115685 "Protein phosphatase 1 regulatory subunit 7" Q15435 2 241149576-241183652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 968.8;Late spermatids: 1709.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA034500, HPA034501" Supported Approved Nucleoli NA NA 960000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA034500: AB_2674192, HPA034501: AB_10670965" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.16e-2)" "unprognostic (3.62e-2)" "unprognostic (4.38e-1)" "unprognostic (8.07e-3)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (9.05e-2)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (4.51e-3)" "unprognostic (1.23e-1)" 59.0 55.9 71.3 54.4 94.7 68.1 50.2 65.5 82.4 46.4 68.3 66.0 58.8 48.5 61.4 80.3 81.3 40.2 100.5 77.5 69.4 64.6 76.0 53.9 78.7 67.2 67.2 37.5 60.0 55.8 42.6 44.5 65.7 94.5 64.2 58.0 63.1 54.0 100.4 64.3 61.0 55.0 66.5 48.7 58.9 158.2 67.2 66.8 65.1 64.4 80.8 58.9 52.9 75.1 117.6 69.5 77.4 98.3 149.7 149.0 106.4 126.3 114.7 85.2 119.8 38.1 145.6 60.0 37.1 108.9 128.0 112.1 127.9 119.6 130.2 156.4 126.1 105.1 112.4 151.4 96.3 147.0 105.9 116.0 92.7 101.1 74.2 115.7 128.5 121.0 108.0 86.2 202.0 155.8 132.0 112.6 106.3 185.7 64.5 90.4 200.9 121.9 159.6 116.7 104.6 82.8 67.6 157.4 120.3 86.4 93.8 156.7 127.7 76.8 72.5 146.1 103.4 90.8 59.6 162.8 215.2 154.1 103.7 107.9 84.9 108.9 64.6 87.6 68.3 71.6 76.5 77.1 81.3 66.5 58.5 67.6 66.5 75.8 96.2 48.4 121.5 89.9 71.3 94.7 65.5 82.4 77.5 69.4 67.2 67.2 65.7 66.5 67.2 75.1 50.5 57.7 54.5 17.6 47.9 27.8 48.6 126.2 25.6 41.5 44.6 36.8 98.4 45.8 105.5 44.1 16.7 89.6 46.9 53.4 121.3 90.6 968.8 83.6 39.3 45.9 25.7 48.0 33.8 145.9 92.4 47.5 34.7 53.4 59.5 48.9 32.9 49.9 100.5 32.0 19.4 68.7 109.9 40.7 46.3 1709.4 51.0 49.4 87.2 13.1 63.7 78.6 80.3 18.1 21.9 94.5 71.3 67.4 54.5 52.1 81.7 120.8 112.2 58.9 72.3 35.1 65.6 315.5 122.5 45.9 38.1 71.6 57.9 117.2 55.3 56.0 ANO7 "IPCA-5, NGEP, PCANAP5, PCANAP5L, TMEM16G" ENSG00000146205 "Anoctamin 7" Q6IWH7 2 241188509-241225377 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.3;prostate: 69.6;stomach 1: 28.1" "Group enriched" "Detected in many" 5 "Gastric mucus-secreting cells: 80.0;Intestinal goblet cells: 53.4" "Cancer enriched" "Detected in many" 19 "prostate cancer: 32.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.2;Hep G2: 2.3;OE19: 2.5" "Low region specificity" "Detected in many" HPA078464 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "HPA078464: " "unprognostic (1.93e-2)" "unprognostic (3.45e-3)" "unprognostic (1.09e-3)" "unprognostic (5.13e-2)" "unprognostic (1.35e-2)" "unprognostic (8.76e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-2)" "unprognostic (8.45e-2)" "unprognostic (2.90e-2)" "unprognostic (4.94e-2)" "unprognostic (4.82e-3)" "unprognostic (6.09e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.53e-2)" 0.3 0.3 0.2 1.0 0.7 3.6 0.2 0.2 1.0 0.3 0.0 16.3 10.7 0.5 0.0 0.2 0.3 0.0 0.2 0.2 0.2 0.2 0.1 0.1 0.0 1.2 0.2 0.5 0.4 0.0 0.2 0.1 0.4 69.6 10.1 0.0 4.9 0.2 0.0 0.2 14.7 0.1 0.3 0.3 28.1 0.2 0.8 0.0 0.2 0.0 0.0 0.2 0.2 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 2.5 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.2 1.0 0.2 0.2 1.2 0.2 0.4 0.3 0.8 1.6 1.2 0.0 0.0 1.6 0.7 0.3 0.8 0.8 1.2 0.2 1.9 2.7 1.6 0.0 0.2 0.0 0.0 0.6 0.1 2.6 0.0 2.7 0.1 0.8 0.7 2.1 3.0 0.0 4.8 4.2 5.6 2.0 80.0 1.9 0.0 12.4 2.9 3.9 1.5 0.0 2.7 53.4 0.0 1.3 0.0 0.0 3.4 0.7 1.8 7.5 0.0 1.4 0.0 1.0 6.9 6.4 1.9 2.2 0.5 11.9 3.6 2.8 0.0 0.6 0.0 0.8 1.0 0.1 1.7 0.1 0.0 0.7 0.3 2.6 2.4 0.8 HDLBP "HBP, VGL" ENSG00000115677 "High density lipoprotein binding protein" Q00341 2 241227264-241317061 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004189, CAB026457" Enhanced Supported Cytosol NA NA 95000 "Cluster 14: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "CAB026457: , HPA004189: AB_1079044" "unprognostic (2.57e-2)" "unprognostic (1.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.51e-1)" "unprognostic (4.46e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (1.70e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-2)" "unprognostic (4.39e-3)" "unprognostic (3.92e-2)" "unprognostic (9.48e-3)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.39e-5)" "prognostic unfavorable (4.12e-4)" 159.7 135.7 54.9 114.0 62.4 105.4 150.9 54.7 55.0 204.1 169.6 181.9 136.2 138.5 180.0 194.2 212.9 156.1 160.3 59.3 55.3 135.1 247.7 112.8 81.2 67.6 65.4 151.4 603.8 164.1 141.6 176.1 62.1 182.0 171.1 66.8 446.8 143.0 367.6 118.6 136.0 171.8 60.2 79.2 231.6 226.5 78.0 74.7 191.3 365.8 111.1 158.6 98.6 76.0 310.0 239.5 237.4 383.7 587.9 715.3 362.6 736.7 719.9 319.7 451.3 233.1 299.2 93.2 88.1 1039.3 334.0 235.2 356.9 465.8 528.2 150.4 236.0 323.0 305.1 535.7 566.7 233.0 251.4 528.8 369.1 466.0 515.9 500.4 448.1 140.9 310.1 120.0 511.9 309.5 120.4 106.1 237.9 290.4 161.2 111.7 511.9 175.5 255.1 380.1 208.4 223.5 332.3 334.5 278.4 304.2 262.6 201.8 585.4 402.1 255.1 551.5 325.3 136.2 130.8 166.5 488.1 161.1 371.8 26.0 39.3 17.4 15.6 41.0 20.3 19.6 17.7 18.8 41.3 12.7 15.5 15.1 22.0 19.2 58.1 26.4 18.1 27.5 54.9 62.4 54.7 55.0 59.3 55.3 67.6 65.4 62.1 60.2 78.0 76.0 53.9 76.9 102.7 38.5 60.6 70.2 117.4 80.4 150.2 41.0 125.3 98.8 220.5 71.4 124.9 75.4 43.8 133.9 34.7 176.2 135.0 106.7 111.0 152.8 178.3 80.8 96.5 72.6 44.5 122.1 166.5 156.3 203.4 168.2 68.4 199.3 86.7 199.3 94.6 69.0 45.9 291.1 30.5 70.3 66.4 398.0 148.8 75.1 56.9 46.9 77.8 53.5 20.6 46.3 58.1 116.5 118.4 174.9 354.7 203.9 136.3 117.9 163.3 40.0 65.7 126.5 117.0 132.1 120.7 192.4 77.6 215.5 50.7 134.0 163.2 156.1 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 FARP2 "FIR, FRG, KIAA0793, PLEKHC3" ENSG00000006607 "FERM, ARH/RhoGEF and pleckstrin domain protein 2" O94887 2 241356285-241494841 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2;Oligodendrocytes: 114.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031226, HPA055592" Approved Approved Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "HPA031226: AB_10602808, HPA055592: AB_2682856" "unprognostic (3.07e-1)" "unprognostic (1.39e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (1.37e-2)" "unprognostic (1.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.83e-1)" "unprognostic (2.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (9.11e-2)" "unprognostic (6.31e-2)" "unprognostic (6.78e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-1)" 9.6 10.3 13.8 11.4 16.8 5.4 9.0 19.3 16.0 10.0 9.8 22.6 20.2 10.6 7.3 14.1 9.2 10.0 7.6 13.2 12.9 11.0 17.1 10.4 11.9 15.6 15.2 11.0 11.4 13.2 8.4 9.0 15.6 10.1 21.3 10.1 9.2 10.0 10.6 22.6 18.9 11.6 11.7 11.6 20.3 28.1 16.2 8.5 6.8 9.9 13.8 14.2 10.1 21.3 20.0 14.3 25.8 17.7 21.9 29.1 23.1 19.7 16.3 20.0 20.6 15.3 23.4 8.5 5.2 38.8 14.1 22.4 35.0 20.6 30.4 13.3 18.1 18.8 25.4 20.3 16.0 17.0 14.1 29.3 15.2 29.2 23.7 9.3 18.4 16.1 21.7 7.6 16.3 16.7 18.3 12.5 12.8 35.3 11.1 20.3 58.2 25.7 25.9 41.0 30.5 20.3 22.1 15.4 59.5 14.9 8.1 16.8 27.9 18.8 14.3 23.8 16.0 13.0 10.0 18.8 17.2 11.5 39.0 6.1 2.1 7.3 1.3 5.1 1.2 4.4 1.4 1.5 3.1 4.9 0.9 1.0 1.3 1.7 2.8 6.4 2.2 1.6 13.8 16.8 19.3 16.0 13.2 12.9 15.6 15.2 15.6 11.7 16.2 21.3 8.9 28.9 5.9 27.4 23.9 15.4 11.4 8.0 16.5 12.7 11.1 8.3 29.6 14.3 12.3 18.4 18.8 5.8 9.7 36.3 3.9 9.3 42.7 12.0 10.6 10.5 28.1 3.4 43.1 12.3 5.4 12.9 45.3 14.0 6.3 15.9 11.0 11.6 4.2 20.2 36.7 38.7 10.2 8.4 9.4 25.0 14.9 11.9 39.2 38.4 8.5 4.9 2.1 128.2 114.0 12.6 24.1 10.5 14.4 12.8 20.9 7.1 17.3 15.1 19.7 21.4 14.1 45.6 19.7 13.8 15.2 11.1 6.0 11.3 26.2 22.4 STK25 "SOK1, YSK1" ENSG00000115694 "Serine/threonine kinase 25" O00506 2 241492670-241509730 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 489.9;tongue: 213.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047147 Uncertain NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA047147: AB_10966137" "unprognostic (1.75e-1)" "unprognostic (8.29e-2)" "prognostic unfavorable (6.03e-4)" "unprognostic (3.42e-2)" "unprognostic (2.71e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (3.91e-8)" "unprognostic (6.16e-2)" "unprognostic (7.15e-3)" "unprognostic (1.11e-1)" "unprognostic (2.58e-3)" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (2.00e-1)" "unprognostic (1.37e-1)" "unprognostic (3.19e-1)" "unprognostic (4.58e-1)" 53.2 50.6 48.2 37.1 48.9 47.0 52.8 35.8 56.7 59.8 27.8 59.8 36.2 62.9 24.0 62.6 60.5 32.9 69.1 50.4 47.1 56.5 50.0 49.6 36.7 37.5 40.9 59.4 70.3 45.9 65.3 38.7 43.3 55.4 30.5 28.9 48.7 40.2 489.9 53.1 50.5 42.1 30.7 61.6 58.7 48.7 46.4 38.5 71.9 213.8 31.8 60.8 56.7 41.2 75.2 46.9 91.1 114.0 109.9 75.9 140.1 122.3 81.8 90.9 103.4 52.3 64.4 28.5 33.7 163.9 82.3 62.9 130.2 132.9 109.9 107.0 136.4 79.7 98.3 136.6 99.3 48.7 59.0 110.1 93.9 88.3 70.3 111.1 208.7 102.6 125.2 24.6 168.8 78.6 73.0 75.9 127.9 69.5 66.3 121.1 116.2 42.6 79.5 62.4 152.8 70.2 59.4 44.2 77.0 102.7 35.7 85.2 245.7 68.2 83.0 79.1 88.3 50.3 12.1 48.8 66.0 39.6 79.1 17.0 16.3 12.9 17.3 15.5 16.3 15.9 15.9 18.5 15.0 16.9 12.3 11.8 5.8 24.6 19.7 11.8 23.3 12.6 48.2 48.9 35.8 56.7 50.4 47.1 37.5 40.9 43.3 30.7 46.4 41.2 43.6 22.4 41.4 23.2 19.7 25.5 29.0 29.7 19.9 48.7 33.2 39.4 36.3 42.9 24.0 25.8 27.1 82.7 19.8 35.2 27.4 46.0 13.8 18.5 28.4 52.7 35.4 48.6 29.8 34.2 80.7 35.1 36.7 25.4 25.4 40.8 45.7 21.5 45.1 32.0 26.1 40.0 20.3 27.3 25.7 14.4 32.6 20.8 19.6 21.5 47.0 58.9 18.6 16.1 27.5 36.9 74.5 39.9 15.8 37.1 43.4 46.1 16.2 41.1 46.0 41.7 35.3 90.2 54.7 31.7 30.4 52.4 25.4 53.2 44.9 29.9 BOK "BCL2L9, BOKL, MGC4631" ENSG00000176720 "BCL2 family apoptosis regulator BOK" Q9UMX3 2 241551424-241574131 "Plasma proteins, Predicted membrane proteins, Transporters" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 218.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 100.8;Oligodendrocytes: 47.0;Proximal tubular cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.3" "Lineage enhanced" "Detected in single" "T-cells: 2.3" "Cell line enhanced" "Detected in many" "TIME: 65.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (6.16e-2)" "unprognostic (3.01e-2)" "unprognostic (1.24e-3)" "unprognostic (6.30e-2)" "unprognostic (8.63e-2)" "unprognostic (1.33e-1)" "unprognostic (2.24e-3)" "unprognostic (1.16e-2)" "unprognostic (8.45e-2)" "unprognostic (2.33e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "prognostic favorable (1.09e-9)" "unprognostic (9.48e-3)" "unprognostic (6.81e-2)" "unprognostic (2.46e-1)" "unprognostic (1.09e-1)" 90.6 7.1 88.4 6.2 138.6 0.4 37.7 110.4 110.3 15.6 51.0 38.0 8.1 34.2 16.3 29.5 18.1 22.7 6.3 77.0 87.8 20.5 97.0 20.1 3.7 146.6 120.6 9.9 16.3 3.8 4.7 5.7 127.1 28.5 5.0 1.2 11.8 25.5 2.6 20.0 9.4 20.4 98.5 6.5 21.5 7.7 115.4 1.1 11.0 3.2 3.4 34.9 18.6 218.8 36.0 8.8 15.7 36.2 26.3 15.6 4.4 28.6 11.3 36.9 37.9 16.2 14.6 0.1 9.7 51.0 9.0 32.9 1.7 28.9 13.8 0.1 0.3 0.1 9.3 42.2 21.8 0.2 1.3 15.9 29.2 15.5 4.4 27.8 44.6 2.4 6.4 0.1 36.7 46.0 0.2 0.2 9.9 40.0 26.8 0.4 25.9 0.2 24.2 0.9 14.0 5.4 13.2 8.5 23.3 18.3 24.4 1.3 65.0 0.1 52.8 0.7 3.2 0.1 0.1 0.1 0.1 0.0 2.1 0.0 0.0 0.0 2.3 0.0 0.2 0.0 0.7 1.0 0.0 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.6 88.4 138.6 110.4 110.3 77.0 87.8 146.6 120.6 127.1 98.5 115.4 218.8 22.5 6.4 32.1 0.3 0.5 7.1 11.5 8.6 5.2 0.2 19.4 10.5 10.2 32.9 6.3 11.0 0.0 2.0 2.5 5.8 15.6 23.2 0.2 6.6 17.6 15.6 11.4 5.3 0.8 11.1 10.5 10.9 5.6 14.4 0.0 2.6 12.5 100.8 0.7 0.0 1.5 3.7 2.0 4.7 1.2 1.5 6.2 0.7 1.8 4.7 0.0 3.9 6.2 7.5 47.0 27.7 2.8 10.5 0.9 26.3 7.1 41.9 1.5 1.3 0.0 11.7 11.2 0.3 8.2 19.8 12.8 6.2 1.6 3.4 6.1 15.1 THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 223.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044982, HPA053448" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nuclear speckles" "HPA044982: AB_10959786, HPA053448: AB_2682154" "unprognostic (3.17e-2)" "unprognostic (1.70e-2)" "unprognostic (6.56e-2)" "unprognostic (1.36e-2)" "unprognostic (8.35e-2)" "unprognostic (7.23e-2)" "unprognostic (1.16e-3)" "unprognostic (3.61e-2)" "unprognostic (7.56e-2)" "unprognostic (2.18e-1)" "unprognostic (3.24e-1)" "unprognostic (2.21e-1)" "prognostic favorable (1.46e-4)" "unprognostic (2.57e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.07e-1)" 34.3 31.8 60.3 19.0 60.4 28.1 35.6 57.7 78.5 34.5 60.2 51.1 42.1 30.9 28.7 53.1 29.0 25.0 106.5 58.9 60.7 96.7 54.0 29.3 22.0 60.0 61.4 33.2 48.4 107.0 37.7 16.1 60.3 43.7 27.1 9.0 42.1 24.1 118.8 46.8 34.9 17.3 56.3 26.5 52.0 40.8 62.7 23.4 31.9 91.6 19.0 41.5 38.9 59.8 47.6 53.4 31.5 58.9 41.5 43.1 53.7 32.1 42.5 46.6 41.4 48.6 41.1 40.5 16.4 50.1 53.8 53.4 63.8 71.4 17.6 33.3 76.9 42.5 35.7 138.7 55.0 48.6 28.5 44.8 55.4 50.2 69.2 32.5 43.9 62.4 76.9 13.1 36.4 84.5 51.1 110.1 57.1 43.9 45.2 55.9 44.1 52.6 100.2 57.0 76.4 50.1 24.7 76.9 65.1 19.4 38.7 52.3 40.0 55.5 36.6 50.7 58.3 32.4 19.9 42.6 40.2 40.4 40.9 31.0 15.7 40.3 27.4 18.0 29.4 21.6 30.3 25.5 16.4 25.0 28.6 23.3 10.2 22.7 24.1 23.2 53.6 16.1 60.3 60.4 57.7 78.5 58.9 60.7 60.0 61.4 60.3 56.3 62.7 59.8 16.6 19.2 21.7 15.7 16.4 20.0 42.1 31.9 21.1 9.9 21.2 17.1 55.9 35.8 28.3 40.5 4.2 23.4 13.2 64.6 223.0 48.0 17.7 37.5 19.6 17.7 28.8 21.5 12.2 27.8 24.6 19.9 35.2 58.9 7.0 16.6 13.6 38.0 17.7 8.4 12.8 52.3 32.6 11.4 10.6 7.7 18.0 14.2 12.4 7.5 15.3 11.1 22.6 11.1 11.5 27.6 44.2 19.5 21.3 38.1 79.0 90.0 21.3 6.8 32.9 16.3 23.3 25.3 29.1 40.0 25.9 27.5 15.1 17.5 60.2 53.4 ATG4B "APG4B, AUTL1, DKFZp586D1822, KIAA0943" ENSG00000168397 "Autophagy related 4B cysteine peptidase" Q9Y4P1 2 241637213-241673857 "Enzymes, Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037195, HPA069803" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "CAB037195: AB_1078237, HPA069803: AB_2686200" "unprognostic (1.51e-1)" "unprognostic (8.80e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "unprognostic (2.67e-3)" "unprognostic (1.07e-3)" "unprognostic (1.06e-1)" "unprognostic (1.61e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-3)" "unprognostic (3.02e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.60e-1)" "unprognostic (6.63e-2)" "unprognostic (1.66e-1)" "prognostic favorable (9.64e-4)" 12.0 17.5 21.4 8.1 21.7 14.7 13.2 20.9 24.7 18.0 20.1 19.7 11.4 16.8 5.3 16.2 16.8 7.6 18.4 21.6 23.0 19.7 18.0 12.4 13.2 23.0 21.4 16.5 16.4 12.1 21.5 7.2 23.6 22.6 5.4 8.5 14.4 9.6 18.7 16.7 18.3 6.7 20.7 19.9 16.1 19.7 22.4 16.1 18.7 7.6 7.8 16.3 14.6 21.5 8.8 15.6 16.9 13.5 15.8 10.5 29.5 23.8 9.8 16.5 12.4 15.0 9.8 7.4 7.2 11.8 10.5 16.5 16.0 20.3 3.8 18.8 31.8 19.6 14.1 40.2 20.1 13.6 12.0 13.8 15.0 9.0 7.1 16.8 11.0 44.3 23.4 5.1 8.6 32.6 33.4 36.9 30.9 23.8 25.9 51.3 25.1 16.2 11.4 14.9 26.2 21.3 17.5 13.9 27.8 14.1 15.5 24.6 15.4 7.1 12.0 14.8 13.3 21.1 17.0 34.6 18.8 21.4 17.6 3.9 17.9 19.2 18.5 15.6 15.9 15.8 14.2 15.6 20.4 16.5 18.0 12.8 12.8 11.8 18.9 17.0 20.4 16.8 21.4 21.7 20.9 24.7 21.6 23.0 23.0 21.4 23.6 20.7 22.4 21.5 23.2 32.1 33.8 41.1 25.6 24.3 27.2 41.3 25.0 22.2 24.4 21.8 16.2 25.8 29.9 27.6 33.3 35.8 33.5 61.8 19.6 37.5 18.1 28.6 21.9 25.3 35.9 31.8 38.5 40.2 28.5 22.6 40.8 43.3 19.0 36.5 20.3 27.9 33.4 42.1 33.8 36.4 42.7 28.5 34.5 25.9 22.1 30.7 28.4 31.9 51.2 24.5 41.2 20.1 41.0 41.5 41.5 24.8 28.6 35.6 70.5 25.1 26.7 26.8 19.7 22.7 22.8 58.3 63.3 19.9 25.4 53.9 29.4 27.6 35.6 32.5 DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 108.6;Extravillous trophoblasts: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA 7000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Mitochondria "HPA042593: AB_10959590, HPA042719: AB_10960633" "unprognostic (1.90e-1)" "unprognostic (6.95e-2)" "unprognostic (4.14e-1)" "unprognostic (8.61e-2)" "unprognostic (1.89e-1)" "unprognostic (9.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (2.64e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-2)" "unprognostic (6.94e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (7.13e-2)" "unprognostic (6.81e-2)" "unprognostic (5.07e-2)" "unprognostic (9.19e-2)" 12.2 16.0 15.6 15.6 17.1 37.0 11.8 16.2 19.8 11.2 16.5 15.1 13.2 10.8 6.1 19.1 10.2 8.6 10.6 14.5 15.0 14.9 18.8 9.7 24.8 16.8 16.0 8.2 9.5 7.5 5.0 11.1 16.1 11.1 12.2 4.3 9.8 7.4 8.1 18.8 14.0 13.4 15.3 17.2 13.3 8.2 16.8 24.1 8.7 6.4 19.2 10.6 11.2 17.2 102.6 112.3 93.6 120.1 30.2 33.3 103.2 82.1 63.2 110.8 125.6 54.8 120.1 48.3 24.6 66.8 126.8 84.4 87.8 102.2 56.7 118.8 104.6 103.9 88.3 105.1 26.3 69.1 83.1 23.7 27.3 102.7 42.4 32.1 104.8 74.4 123.6 38.4 114.1 112.6 132.2 125.0 100.7 113.1 94.2 111.4 139.8 71.8 62.3 59.5 115.0 74.0 53.4 81.5 67.9 27.0 74.2 120.0 66.5 147.5 110.4 99.0 152.5 47.3 49.1 144.6 122.4 112.2 184.9 20.5 26.2 17.4 30.4 46.7 29.6 35.6 28.5 32.6 19.7 36.7 28.1 25.0 4.2 32.6 37.1 38.5 42.1 28.5 15.6 17.1 16.2 19.8 14.5 15.0 16.8 16.0 16.1 15.3 16.8 17.2 28.9 9.6 5.8 8.1 21.4 15.2 17.7 47.7 16.5 19.1 36.3 44.8 11.0 24.3 22.2 25.8 2.1 79.5 24.0 22.9 21.5 39.6 2.1 17.6 25.0 29.2 14.4 108.6 3.3 34.1 149.1 26.9 25.5 22.3 15.2 52.3 23.9 22.3 84.9 5.0 4.7 35.7 36.7 17.0 13.9 2.1 16.4 21.7 23.2 5.6 39.3 23.0 38.1 6.0 9.2 33.7 10.6 19.2 37.6 21.7 12.7 37.7 12.9 17.4 26.3 21.4 31.2 27.5 63.4 32.6 11.9 27.5 17.4 28.2 52.2 19.5 ING5 "FLJ23842, p28ING5" ENSG00000168395 "Inhibitor of growth family member 5" Q8WYH8 2 241687085-241729478 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 21.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042685 Approved NA NA "Cluster 38: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "HPA042685: AB_10797507" "unprognostic (1.87e-2)" "unprognostic (3.66e-1)" "unprognostic (1.65e-3)" "unprognostic (9.15e-3)" "unprognostic (1.79e-1)" "unprognostic (1.07e-3)" "prognostic unfavorable (2.86e-5)" "unprognostic (8.25e-2)" "unprognostic (2.30e-2)" "unprognostic (7.87e-2)" "prognostic favorable (1.60e-4)" "unprognostic (2.15e-1)" "unprognostic (5.88e-2)" "unprognostic (8.43e-2)" "unprognostic (5.01e-2)" "unprognostic (5.90e-2)" "unprognostic (4.74e-3)" 12.4 11.3 16.7 8.9 17.1 12.1 12.6 20.5 18.2 19.4 15.3 13.8 9.6 15.0 15.8 13.8 18.8 7.3 12.6 16.4 16.6 14.8 17.1 12.2 12.9 14.7 13.9 25.2 24.0 10.7 24.6 7.9 15.5 21.9 9.1 10.1 19.8 9.8 14.3 18.7 15.4 8.1 11.7 15.7 16.8 9.7 15.5 12.0 23.2 9.5 10.8 14.4 16.2 18.0 12.0 10.9 24.4 14.9 18.5 21.1 30.4 13.2 10.5 13.0 10.4 11.5 11.6 12.0 4.6 12.4 14.0 17.7 22.9 11.8 15.8 12.9 21.6 28.7 17.2 35.0 15.7 30.6 18.2 18.1 18.7 12.8 20.8 15.2 14.4 19.9 28.1 8.0 12.4 20.2 24.6 42.5 28.6 20.5 8.0 42.9 30.1 11.0 12.2 19.2 31.4 19.0 7.0 13.7 18.8 16.0 9.4 20.3 10.2 17.3 18.7 11.2 14.5 17.7 6.7 33.8 12.4 18.4 13.0 21.5 4.0 8.8 2.5 3.2 3.0 3.3 4.2 3.4 2.3 3.7 4.6 3.1 3.9 2.5 3.5 3.7 5.8 2.8 16.7 17.1 20.5 18.2 16.4 16.6 14.7 13.9 15.5 11.7 15.5 18.0 13.4 44.8 33.7 25.1 25.4 9.4 34.6 10.0 21.1 14.7 24.6 26.4 13.9 14.3 19.5 18.4 14.6 20.4 21.3 15.1 31.3 9.3 26.7 23.4 31.6 12.4 8.4 11.3 24.2 10.1 15.3 17.6 13.3 25.1 15.8 22.9 13.6 12.3 7.2 15.2 22.6 16.7 16.2 7.7 7.0 10.4 17.1 11.6 8.8 4.7 8.8 16.3 6.2 18.6 26.9 8.9 9.4 11.3 20.1 26.4 11.6 17.7 11.5 18.8 19.7 22.5 17.4 7.5 11.9 18.1 14.2 17.4 19.9 17.3 15.6 17.7 D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056216, HPA060548" Uncertain Supported Mitochondria "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA056216: AB_2683070, HPA060548: AB_2732650" "unprognostic (2.85e-1)" "unprognostic (3.35e-2)" "unprognostic (6.98e-3)" "unprognostic (7.88e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.11e-4)" "unprognostic (2.49e-3)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (7.82e-3)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (9.60e-2)" "unprognostic (3.05e-2)" 11.5 17.7 6.9 11.2 8.0 18.6 7.6 6.2 7.3 10.5 14.9 16.6 11.4 11.8 13.0 15.0 16.1 14.1 11.4 6.6 6.1 15.9 19.1 10.6 12.0 8.4 6.9 14.8 16.6 15.2 10.5 8.9 6.6 14.6 14.6 3.2 18.7 14.9 33.8 39.4 14.9 9.3 6.1 15.1 14.7 4.9 7.3 7.4 18.0 23.7 11.5 8.9 9.6 8.6 10.2 10.5 6.2 9.6 14.7 7.9 21.5 9.7 12.2 9.6 7.7 11.8 21.9 8.3 4.4 9.7 11.0 23.2 5.9 7.8 4.0 8.8 5.7 15.9 11.3 20.5 8.2 19.0 12.1 14.1 13.7 7.6 7.3 18.5 9.5 13.1 20.7 5.3 8.6 16.8 16.0 19.7 3.0 13.8 20.8 19.5 6.9 16.2 17.6 36.7 20.4 7.2 9.4 23.8 6.6 4.1 14.7 6.7 4.1 14.9 5.6 7.9 5.8 9.9 1.9 13.4 10.3 20.8 10.0 0.0 0.2 0.0 0.2 0.2 0.4 2.5 0.1 1.0 0.4 0.1 0.6 0.2 0.0 0.0 0.3 0.1 0.8 0.1 6.9 8.0 6.2 7.3 6.6 6.1 8.4 6.9 6.6 6.1 7.3 8.6 10.4 9.6 14.3 33.3 10.4 19.8 23.5 13.7 25.6 14.3 22.8 22.7 10.6 25.8 16.3 18.4 14.6 44.0 13.0 40.9 23.5 10.5 3.6 12.5 13.2 9.7 31.8 6.9 7.1 8.7 15.9 15.7 23.0 19.2 5.7 28.0 13.2 46.0 18.2 11.8 9.9 56.4 14.2 10.8 7.5 4.8 16.8 12.6 3.6 15.9 5.3 37.4 8.2 28.6 12.8 6.7 32.0 18.0 15.0 19.3 26.4 31.4 13.9 12.0 6.6 14.0 11.7 2.1 7.0 25.7 14.8 22.6 14.0 27.0 49.9 22.2 GAL3ST2 GP3ST ENSG00000154252 "Galactose-3-O-sulfotransferase 2" Q9H3Q3 2 241776822-241804287 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11 "intestine: 9.4" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Oligodendrocyte precursor cells: 1.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 6.7;ovarian cancer: 4.9;stomach cancer: 2.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Hep G2: 3.7;HMC-1: 10.5" "Not detected" "Not detected" HPA071809 Enhanced "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA071809: AB_2686450" "unprognostic (5.22e-3)" "unprognostic (6.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.04e-3)" "unprognostic (3.04e-4)" "unprognostic (3.45e-2)" "unprognostic (2.48e-2)" "unprognostic (2.87e-1)" "unprognostic (4.13e-2)" "unprognostic (2.25e-3)" "unprognostic (2.58e-1)" "unprognostic (4.99e-2)" "unprognostic (2.87e-11)" "unprognostic (4.32e-2)" "unprognostic (1.55e-1)" "unprognostic (5.99e-3)" "unprognostic (3.49e-1)" 0.5 0.3 0.4 0.8 0.3 0.2 0.0 0.0 0.6 0.5 0.0 9.4 0.0 0.1 0.0 0.0 0.5 0.4 0.1 0.2 0.3 0.3 0.5 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 3.7 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 3.7 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.6 0.2 0.3 0.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 NEU4 ENSG00000204099 "Neuraminidase 4" Q8WWR8 2 241809065-241817413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 75.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 74.6;Enteroendocrine cells: 34.4;Hepatocytes: 124.4;Intestinal goblet cells: 38.5;Oligodendrocyte precursor cells: 50.3;Paneth cells: 58.0;Proximal enterocytes: 76.0;Undifferentiated cells: 38.4" "Group enriched" "Detected in some" 7 "colorectal cancer: 2.3;glioma: 6.0;liver cancer: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "Hep G2: 57.7;HMC-1: 32.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA037394 Enhanced NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037394: AB_2675455" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.85e-1)" "unprognostic (3.68e-4)" "unprognostic (3.76e-2)" "unprognostic (1.57e-1)" "unprognostic (8.70e-2)" "unprognostic (8.62e-2)" "unprognostic (1.74e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-2)" "unprognostic (2.92e-1)" "unprognostic (8.11e-4)" "unprognostic (2.00e-2)" "unprognostic (3.82e-1)" "unprognostic (6.64e-3)" "unprognostic (1.55e-2)" 0.9 0.2 2.3 0.1 2.5 3.5 0.2 2.2 4.4 0.5 0.6 15.5 10.7 0.2 0.0 0.0 0.7 0.4 0.3 2.1 2.5 1.8 75.8 0.4 0.0 5.0 2.8 0.3 0.1 0.0 1.1 0.0 2.7 0.4 2.2 0.1 0.8 0.0 9.0 0.1 9.2 0.0 2.6 0.3 0.1 0.7 2.7 0.0 0.3 0.8 0.0 0.1 0.1 2.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 57.7 0.0 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.5 2.2 4.4 2.1 2.5 5.0 2.8 2.7 2.6 2.7 2.9 0.2 0.0 0.0 1.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.1 0.6 1.5 0.7 1.8 0.0 0.0 1.1 74.6 3.9 0.0 0.1 0.0 0.1 0.3 34.4 0.0 0.4 0.0 0.0 0.2 0.5 0.0 1.3 0.1 1.1 124.4 1.5 0.0 0.4 38.5 2.0 4.2 0.7 0.2 0.6 4.0 0.0 0.0 0.0 26.2 0.0 50.3 0.1 0.0 58.0 0.7 0.4 0.0 76.0 23.6 0.2 1.3 0.0 3.6 0.4 0.5 0.5 0.0 0.0 0.0 1.3 0.0 38.4 0.1 PDCD1 "CD279, hSLE1, PD-1, PD1, SLEB2" ENSG00000188389 "Programmed cell death 1" Q15116 2 241849884-241858894 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Immunity" "FDA approved drug targets, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.7;lymphoid tissue: 16.1" "Group enriched" "Detected in some" 4 "Plasma cells: 9.5;T-cells: 34.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.4" "Group enriched" "Detected in many" 5 "gdT-cell: 4.4;MAIT T-cell: 4.8;memory CD4 T-cell: 8.7;memory CD8 T-cell: 12.4;T-reg: 4.3" "Lineage enriched" "Detected in single" 55 "T-cells: 12.4" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;MOLT-4: 2.4;RPMI-8226: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035981, CAB038418, CAB076386" Enhanced NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB038418: AB_1160824, CAB076386: AB_881954, HPA035981: AB_10669664" "unprognostic (2.90e-3)" "unprognostic (4.50e-3)" "unprognostic (7.78e-2)" "prognostic favorable (9.44e-5)" "unprognostic (7.18e-3)" "unprognostic (1.31e-3)" "unprognostic (3.83e-2)" "unprognostic (7.33e-2)" "unprognostic (5.82e-3)" "unprognostic (3.75e-2)" "unprognostic (6.57e-2)" "unprognostic (3.94e-1)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.20e-2)" "unprognostic (3.10e-1)" "unprognostic (5.35e-2)" "unprognostic (5.06e-3)" 1.2 0.3 0.0 3.2 0.2 0.9 0.4 0.0 0.1 0.6 0.2 0.8 0.3 0.4 0.0 0.8 0.6 0.3 6.7 0.1 0.1 0.7 0.4 1.8 16.1 0.1 1.4 0.2 0.3 0.0 1.5 0.0 0.2 0.7 0.1 0.0 1.0 0.2 0.1 0.3 3.8 0.2 0.1 7.0 1.8 0.3 0.4 3.1 1.5 0.0 4.0 1.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.3 2.4 0.0 0.0 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 4.8 0.2 8.7 12.4 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 4.3 2.1 0.0 0.2 0.0 0.1 0.1 0.1 0.1 1.4 0.2 0.1 0.4 0.2 0.4 0.0 0.6 0.0 3.6 0.4 0.3 0.0 0.0 0.0 0.3 0.5 0.6 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 5.3 0.0 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.6 0.0 34.7 0.0 0.0 0.1 RTP5 "C2orf85, CXXC11, FLJ33590, Z3CXXC5" ENSG00000188011 "Receptor transporter protein 5 (putative)" Q14D33 2 241869600-241873823 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "brain: 32.9" "Cell type enhanced" "Detected in some" "Early spermatids: 8.8;Inhibitory neurons: 4.1;Late spermatids: 2.8;Oligodendrocyte precursor cells: 17.6" "Cancer enriched" "Detected in single" 10 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "MOLT-4: 1.3;SCLC-21H: 2.6" "Low region specificity" "Detected in all" HPA050902 Enhanced NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 68: Oligodendrocytes - Mixed function" "HPA050902: AB_2681268" "unprognostic (3.26e-2)" "unprognostic (5.38e-4)" "unprognostic (2.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.01e-1)" "unprognostic (9.40e-4)" "unprognostic (8.68e-3)" "unprognostic (2.04e-1)" "unprognostic (6.34e-4)" "unprognostic (3.30e-1)" "unprognostic (9.01e-3)" "unprognostic (3.91e-1)" "unprognostic (9.08e-8)" "unprognostic (1.81e-1)" "unprognostic (1.77e-1)" "unprognostic (2.68e-2)" "unprognostic (3.72e-2)" 0.3 0.0 25.8 0.1 10.0 0.3 0.1 0.0 18.9 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 29.7 32.9 0.1 0.1 0.5 0.5 5.1 17.3 0.0 0.0 0.0 0.1 0.0 16.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 6.2 1.4 0.3 0.4 25.4 0.3 0.1 0.0 0.0 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.8 10.0 0.0 18.9 29.7 32.9 5.1 17.3 16.3 6.2 25.4 1.3 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.8 0.0 0.4 0.0 1.0 0.0 0.0 0.0 17.6 0.3 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 FAM240C ENSG00000216921 "Family with sequence similarity 240 member C" A0A1B0GVR7 2 241893988-241902551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 225.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "JURKAT: 1.5;REH: 2.4;SCLC-21H: 1.6" HPA073342 Approved Nucleoplasm NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 14: REH - Unknown function" Nucleoplasm "HPA073342: " "unprognostic (9.31e-2)" "unprognostic (4.59e-2)" "unprognostic (1.61e-2)" "unprognostic (1.10e-1)" "unprognostic (7.48e-2)" "unprognostic (3.12e-1)" "unprognostic (2.93e-2)" "unprognostic (4.75e-2)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (2.04e-2)" "unprognostic (5.12e-2)" "unprognostic (5.44e-2)" "unprognostic (8.45e-2)" "unprognostic (2.44e-1)" "unprognostic (3.29e-1)" 3.5 0.7 5.9 0.1 6.9 0.3 3.9 6.4 8.2 1.4 5.6 0.2 0.2 1.9 0.0 4.0 1.7 0.1 1.3 5.4 5.9 0.1 0.2 0.1 0.4 6.2 6.4 1.6 36.8 0.5 0.4 0.2 6.4 3.5 0.0 0.6 5.4 3.9 10.2 3.1 0.2 0.1 5.6 0.3 0.4 1.3 6.3 3.4 6.9 225.1 0.2 0.4 1.0 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.2 0.2 0.0 0.7 0.5 0.0 0.2 0.0 0.0 2.4 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.3 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.9 6.4 8.2 5.4 5.9 6.2 6.4 6.4 5.6 6.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0