Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" OR11H1 OR22-1 ENSG00000130538 "Olfactory receptor family 11 subfamily H member 1" 22 15528192-15529139 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 POTEH "A26C3, ACTBL1, CT104.7, POTE22" ENSG00000198062 "POTE ankyrin domain family member H" Q6S545 22 15690026-15721631 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "prostate: 2.1;testis: 1.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 28 "prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Testis - DNA repair" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (4.66e-2)" "unprognostic (1.02e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCT8L2 CESK1 ENSG00000198445 "Chaperonin containing TCP1 subunit 8 like 2" Q96SF2 22 16590751-16592810 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 215 "testis: 21.4" "Group enriched" "Detected in some" 53 "Early spermatids: 182.6;Late spermatids: 87.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "unprognostic (3.29e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 182.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.2 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 XKR3 "MGC57211, XTES" ENSG00000172967 "XK related 3" Q5GH77 22 16783412-16821699 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 43 "testis: 8.1" "Cell type enriched" "Detected in some" 10 "Early spermatids: 159.6" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 15 "Karpas-707: 230.8" "HPA003379, HPA035081" Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA003379: AB_10602682, HPA035081: AB_2674451" "unprognostic (4.57e-1)" "unprognostic (3.37e-1)" "unprognostic (3.11e-2)" "unprognostic (3.13e-2)" "unprognostic (5.77e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.5 0.0 0.0 15.2 230.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.9 0.1 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 159.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.3 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GAB4 ENSG00000215568 "GRB2 associated binding protein family member 4" Q2WGN9 22 16961936-17008222 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "testis: 2.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.2;Late spermatids: 25.1;Spermatocytes: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044621 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA044621: AB_10967265" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 25.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IL17RA "CD217, CDw217, hIL-17R, IL-17RA, IL17R" ENSG00000177663 "Interleukin 17 receptor A" Q96F46 22 17084954-17115694 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.8" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.9;Kupffer cells: 81.4;Macrophages: 61.4;monocytes: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HL-60: 59.9;NB-4: 52.5;THP-1: 74.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB024996 Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" NA NA 62000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "CAB024996: " "unprognostic (1.92e-1)" "unprognostic (3.15e-1)" "unprognostic (1.65e-2)" "unprognostic (9.83e-2)" "unprognostic (7.66e-2)" "unprognostic (5.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-2)" "unprognostic (8.52e-2)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.96e-2)" "prognostic favorable (8.35e-4)" "unprognostic (2.16e-2)" "unprognostic (1.27e-1)" "unprognostic (6.51e-3)" 9.1 5.6 5.5 9.6 11.3 31.8 6.9 5.7 7.5 5.4 6.8 4.7 3.8 5.4 5.0 5.2 6.0 3.6 4.6 6.3 5.5 3.7 5.7 10.0 6.9 9.8 7.3 4.5 5.2 3.9 3.8 3.5 8.9 5.0 3.4 1.5 5.2 2.8 1.8 6.9 6.2 5.3 7.7 16.6 5.6 2.0 7.7 15.4 4.2 2.6 5.6 4.6 4.7 9.6 7.9 4.5 4.1 5.1 8.0 4.6 5.1 11.5 7.4 5.3 6.8 4.4 5.1 7.1 4.6 11.6 6.9 12.4 5.6 5.4 3.7 11.6 6.6 0.0 2.6 2.8 9.2 59.9 17.8 6.8 7.9 4.7 3.7 5.2 5.7 5.6 3.0 7.3 5.5 6.7 7.2 52.5 2.2 10.1 4.3 1.6 0.8 1.3 5.1 5.8 2.8 0.1 8.0 6.7 5.7 4.6 5.3 74.7 15.9 4.1 5.8 6.1 4.3 5.8 3.4 3.3 6.0 28.3 4.5 8.5 7.4 7.2 1.1 3.4 0.9 0.5 1.5 1.2 3.9 0.4 2.4 1.8 16.5 1.5 3.5 1.8 1.0 2.6 5.5 11.3 5.7 7.5 6.3 5.5 9.8 7.3 8.9 7.7 7.7 9.6 14.0 12.8 14.1 2.9 13.8 8.8 6.6 10.2 10.8 3.9 7.2 5.8 6.1 10.0 8.6 5.5 8.4 6.1 18.7 23.6 0.0 8.7 4.0 7.2 8.1 13.7 13.2 9.2 8.3 12.6 11.9 13.6 29.0 9.7 7.6 58.9 17.5 11.1 34.0 3.3 6.4 13.9 6.1 81.4 16.2 2.1 9.0 61.4 8.8 41.2 114.2 4.3 28.8 12.5 11.4 12.2 12.4 4.5 10.3 9.1 14.7 3.4 8.0 2.9 13.1 10.4 10.0 3.0 13.4 9.0 6.8 6.4 25.4 8.1 12.4 9.6 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 43.0;Ductal cells: 35.2;Extravillous trophoblasts: 42.2;Granulosa cells: 37.0;Hofbauer cells: 42.3;Proximal tubular cells: 41.1;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005548 Approved Approved Mitochondria "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "HPA005548: AB_1078497" "unprognostic (4.04e-2)" "unprognostic (5.04e-2)" "unprognostic (4.54e-3)" "unprognostic (6.61e-2)" "unprognostic (1.20e-1)" "unprognostic (5.71e-2)" "unprognostic (1.04e-3)" "unprognostic (7.35e-2)" "unprognostic (1.70e-1)" "unprognostic (4.98e-2)" "unprognostic (5.76e-2)" "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (7.07e-3)" "unprognostic (1.71e-1)" "unprognostic (1.20e-2)" "unprognostic (7.21e-3)" 17.4 29.7 15.0 13.2 15.3 16.5 17.3 15.4 15.7 12.9 16.7 21.5 26.5 14.6 6.8 21.7 13.6 9.8 45.0 15.4 14.8 19.8 40.5 12.6 14.5 15.4 14.9 12.2 20.9 17.5 11.6 8.1 14.6 15.5 14.1 5.7 18.6 10.0 46.9 23.0 17.2 11.4 14.8 19.3 19.9 15.9 15.9 13.6 10.1 55.7 12.0 16.5 14.1 15.0 64.0 41.5 30.5 41.5 17.7 10.8 38.8 17.9 19.6 47.1 50.2 61.1 23.3 103.9 29.3 21.6 23.0 44.0 38.7 42.0 21.8 31.6 56.7 0.0 30.7 0.0 29.4 47.6 23.5 26.1 51.1 21.0 23.1 26.4 33.3 67.4 31.0 26.2 24.9 62.1 84.2 97.2 46.6 97.9 36.7 47.4 45.8 26.3 32.2 34.7 61.4 46.5 34.9 49.9 54.3 23.9 50.1 58.5 29.1 39.7 29.4 28.2 31.3 41.3 48.5 77.8 32.0 0.1 34.2 12.3 86.2 4.7 28.4 56.7 35.6 24.6 26.4 25.8 74.5 23.6 34.3 29.3 4.5 30.7 31.4 30.9 29.7 48.0 15.0 15.3 15.4 15.7 15.4 14.8 15.4 14.9 14.6 14.8 15.9 15.0 21.5 6.4 2.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 23.9 22.4 0.0 0.0 5.0 5.5 0.0 26.5 9.3 0.0 43.0 35.2 0.0 8.4 14.9 9.2 0.0 0.0 0.0 28.2 42.2 7.7 0.0 11.5 5.1 37.0 0.0 0.0 42.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 5.2 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.5 0.0 0.0 41.1 1.5 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 15.7 3.4 55.8 0.0 0.0 ADA2 "ADGF, CECR1, IDGFL" ENSG00000093072 "Adenosine deaminase 2" Q9NZK5 22 17178790-17258235 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 106.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Glandular and luminal cells: 22.0;Hofbauer cells: 57.6;Macrophages: 62.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.7;EFO-21: 21.4;HUVEC TERT2: 24.0;Karpas-707: 44.9;MOLT-4: 38.9;U-266/70: 23.8;U-937: 39.6" "Low region specificity" "Detected in all" HPA007888 Uncertain "Secreted to blood" NA NA 58000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "HPA007888: AB_1078495" "unprognostic (1.03e-3)" "unprognostic (2.00e-3)" "unprognostic (6.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-2)" "unprognostic (7.01e-3)" "unprognostic (4.48e-2)" "unprognostic (3.09e-3)" "unprognostic (3.80e-2)" "prognostic favorable (9.26e-4)" "prognostic favorable (8.91e-4)" "unprognostic (1.41e-1)" "unprognostic (1.49e-1)" "unprognostic (4.86e-3)" "unprognostic (1.96e-2)" "unprognostic (4.83e-2)" "unprognostic (2.51e-1)" 14.0 11.3 8.3 39.4 9.9 22.8 17.6 10.6 7.9 22.0 20.5 28.3 18.1 19.9 2.7 12.0 51.5 32.1 39.6 7.8 10.9 14.5 21.1 54.9 47.3 16.3 11.4 12.1 13.9 5.4 22.5 15.2 14.7 15.4 34.3 11.0 15.6 17.1 3.4 4.7 26.1 23.4 13.7 106.3 19.6 18.4 12.9 53.7 16.9 4.3 60.7 34.7 6.5 21.1 0.0 0.0 6.4 0.0 0.2 0.8 0.3 2.3 0.1 0.0 0.0 0.0 23.7 6.0 21.4 7.2 0.0 0.5 0.2 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.0 0.3 0.3 11.3 0.1 0.0 0.1 0.1 24.0 9.0 0.1 44.9 0.9 0.0 38.9 1.1 17.8 0.0 0.1 1.2 0.0 6.5 0.0 9.3 10.9 0.1 0.1 0.0 0.0 19.1 0.2 9.7 3.0 0.1 0.2 0.0 0.0 23.8 2.3 1.7 0.0 39.6 0.0 17.5 212.9 11.3 34.6 204.9 26.8 25.8 27.4 34.1 139.1 19.7 31.6 32.4 10.5 44.9 176.1 57.4 17.2 170.7 8.3 9.9 10.6 7.9 7.8 10.9 16.3 11.4 14.7 13.7 12.9 21.1 8.7 0.0 16.8 0.0 7.2 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.0 0.0 11.2 5.5 0.0 0.4 13.7 0.0 7.9 1.7 0.0 27.6 6.6 2.2 0.0 0.0 0.0 5.2 0.9 2.1 0.0 22.0 5.1 12.6 0.0 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 12.4 0.0 0.0 3.1 15.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.8 8.2 3.1 0.0 0.0 CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558149 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 15.6;skeletal muscle: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 109.4;Cone photoreceptor cells: 168.9;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 137.7;Rod photoreceptor cells: 94.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 14.4;K-562: 8.3;NTERA-2: 22.8;SCLC-21H: 10.1;SuSa: 9.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA002943: AB_1078496" "unprognostic (2.46e-2)" "unprognostic (4.10e-2)" "unprognostic (7.99e-2)" "unprognostic (1.92e-3)" "unprognostic (7.48e-3)" "unprognostic (2.46e-3)" "unprognostic (2.49e-1)" "unprognostic (6.67e-2)" "unprognostic (8.18e-2)" "unprognostic (3.94e-1)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (8.13e-6)" "unprognostic (1.13e-1)" "unprognostic (1.59e-1)" "unprognostic (6.56e-2)" "unprognostic (1.94e-2)" 0.7 0.4 5.2 0.2 12.8 0.5 1.0 22.5 8.3 1.4 1.2 1.2 0.2 2.3 0.6 0.4 1.7 0.2 3.4 5.3 8.0 1.3 7.6 2.6 0.1 9.8 9.0 2.9 2.6 0.0 6.4 1.0 8.7 1.0 0.3 15.6 0.9 0.2 21.8 0.9 0.5 0.9 5.4 0.4 0.5 3.5 9.8 0.2 2.2 10.6 0.2 1.3 1.0 12.7 0.2 0.1 15.5 5.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.7 0.1 14.4 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 8.3 0.0 0.0 0.1 0.0 0.5 22.8 0.0 0.0 1.8 1.0 0.1 0.0 5.1 10.1 0.0 0.0 0.2 0.9 9.0 1.6 2.5 0.1 0.1 3.4 0.0 0.0 5.8 1.4 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 12.8 22.5 8.3 5.3 8.0 9.8 9.0 8.7 5.4 9.8 12.7 1.9 6.4 10.6 109.4 0.3 0.0 1.1 0.2 0.0 22.1 0.7 0.6 11.8 0.0 0.8 1.8 168.9 10.1 0.0 0.0 0.0 0.1 6.3 6.3 6.2 2.0 0.0 0.0 2.3 0.2 2.5 3.1 0.0 17.2 0.0 3.5 4.2 10.7 0.7 5.0 4.3 0.0 0.0 0.3 0.3 4.0 1.2 1.4 0.0 34.7 0.2 18.3 0.0 120.1 137.7 0.1 0.0 1.2 0.8 1.8 0.0 1.4 0.9 94.1 6.6 33.9 3.2 1.9 15.9 0.1 0.1 33.0 0.2 0.4 0.0 3.6 SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 143.8;choroid plexus: 90.7;liver: 111.5" "Group enriched" "Detected in many" 4 "Astrocytes: 195.2;Hepatocytes: 72.8" "Group enriched" "Detected in some" 5 "glioma: 10.6;liver cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 3.8;BEWO: 8.5" "Low region specificity" "Detected in all" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria Nucleoplasm "HPA068110: " "unprognostic (2.15e-1)" "unprognostic (6.07e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "unprognostic (3.79e-1)" "unprognostic (3.98e-2)" "unprognostic (1.00e-1)" "unprognostic (1.89e-1)" "unprognostic (1.45e-2)" "unprognostic (2.72e-2)" "unprognostic (8.70e-4)" "unprognostic (1.44e-1)" "unprognostic (3.92e-2)" "unprognostic (1.67e-2)" "unprognostic (1.29e-1)" "unprognostic (5.24e-2)" "unprognostic (1.62e-1)" 14.4 1.0 130.1 0.3 132.1 0.1 7.2 116.5 141.1 2.5 90.7 2.9 0.3 2.9 0.2 0.3 3.8 0.9 2.8 119.4 123.3 1.9 111.5 1.2 0.3 121.7 129.2 1.2 1.1 0.2 1.5 0.1 112.5 7.8 0.1 1.9 0.5 0.4 6.2 1.2 1.9 0.5 106.5 4.8 1.5 4.2 143.8 0.3 0.6 4.0 0.1 0.8 1.4 110.7 0.3 0.6 2.2 0.4 3.8 0.0 8.5 0.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.5 0.7 0.0 0.0 0.0 0.3 1.0 0.3 0.3 0.5 1.5 0.3 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.4 0.3 0.0 0.4 0.1 0.5 2.0 0.9 1.4 2.9 0.8 0.0 0.1 0.4 0.8 0.3 0.2 0.4 0.7 1.6 2.5 1.0 0.1 0.1 0.3 0.2 0.3 0.9 1.2 0.0 1.8 0.2 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 130.1 132.1 116.5 141.1 119.4 123.3 121.7 129.2 112.5 106.5 143.8 110.7 1.0 28.9 10.3 195.2 0.3 0.0 0.3 0.1 0.6 0.6 0.3 0.0 1.5 5.7 7.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.6 0.4 0.9 1.7 0.0 10.7 2.0 0.0 0.3 4.7 0.0 0.7 6.3 8.5 3.6 72.8 0.3 0.0 3.0 0.3 0.0 4.1 0.3 0.6 0.9 3.9 0.0 10.3 0.1 2.2 1.0 13.0 11.5 0.0 0.0 2.6 0.1 4.3 0.1 0.8 15.8 3.4 0.0 2.7 2.5 4.8 5.9 0.0 0.1 1.8 2.6 2.6 0.0 0.2 ATP6V1E1 "ATP6E, ATP6E2, ATP6V1E, P31, Vma4" ENSG00000131100 "ATPase H+ transporting V1 subunit E1" P36543 22 17592136-17628749 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 461.8;Proximal tubular cells: 411.3;Syncytiotrophoblasts: 479.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009528, CAB018699, HPA029196" Enhanced Approved Nucleoplasm NA NA 34000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB009528: AB_2062678, CAB018699: AB_781534, HPA029196: AB_2672944" "unprognostic (1.53e-3)" "unprognostic (5.78e-3)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.24e-3)" "prognostic unfavorable (1.56e-5)" "unprognostic (2.17e-1)" "unprognostic (2.09e-1)" "unprognostic (3.37e-2)" "unprognostic (7.72e-3)" "prognostic favorable (4.18e-4)" "prognostic favorable (7.66e-8)" "unprognostic (3.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.58e-2)" "unprognostic (2.75e-1)" 119.5 165.0 209.8 68.3 220.9 90.4 109.5 214.3 287.3 101.7 200.4 128.9 56.6 112.2 135.8 117.2 96.0 84.7 224.9 231.8 226.9 230.5 85.6 110.3 88.6 220.3 202.3 81.9 59.5 239.9 117.1 113.8 230.8 95.0 99.7 128.4 83.7 126.4 232.8 120.3 83.1 121.0 215.9 99.0 101.8 67.3 218.1 108.2 100.8 178.6 109.5 114.5 97.6 245.6 121.8 108.6 96.4 94.3 314.4 169.6 106.0 159.3 212.0 198.7 228.0 137.3 97.5 76.1 132.8 215.0 251.8 187.9 152.8 140.2 174.9 145.9 173.3 137.1 97.5 182.7 459.9 159.8 226.5 212.9 267.7 192.4 138.7 220.9 170.2 95.0 174.8 150.3 341.9 127.4 136.5 114.5 71.0 269.6 152.6 80.3 140.7 45.7 331.6 189.0 70.3 122.7 146.0 101.0 358.9 187.0 98.6 180.4 146.3 137.5 72.6 174.0 119.2 145.7 275.5 96.3 221.2 76.7 189.3 178.1 106.3 184.7 64.0 100.9 63.0 78.7 64.7 61.5 83.6 59.8 60.8 63.7 137.6 76.0 120.5 81.2 97.7 112.8 209.8 220.9 214.3 287.3 231.8 226.9 220.3 202.3 230.8 215.9 218.1 245.6 66.5 76.9 83.4 13.4 47.1 41.9 77.6 121.8 19.9 54.6 33.9 34.8 126.8 74.4 83.9 138.0 27.1 235.1 63.8 105.2 461.8 143.8 7.6 74.3 56.9 69.3 41.9 49.4 24.9 119.7 143.9 60.8 40.8 79.2 90.5 41.6 72.5 46.8 186.8 53.8 24.4 54.0 116.0 75.1 52.1 17.9 94.1 91.9 80.0 15.0 144.1 94.1 85.5 13.0 31.9 154.7 104.7 97.8 38.3 60.1 65.4 411.3 78.8 50.4 59.2 39.0 74.5 71.7 74.7 34.3 51.6 479.1 54.6 57.6 40.1 93.1 BCL2L13 "BCL-RAMBO, MIL1" ENSG00000099968 "BCL2 like 13" Q9BXK5 22 17628855-17730855 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002052, HPA030994, HPA050377" Uncertain Enhanced Mitochondria NA NA 100000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 56: Bipolar cells - Visual perception" Mitochondria "CAB002052: AB_563431, HPA030994: AB_10795024, HPA050377: AB_2681107" "unprognostic (1.59e-1)" "unprognostic (8.17e-2)" "unprognostic (2.18e-3)" "unprognostic (1.86e-1)" "unprognostic (6.27e-2)" "unprognostic (2.69e-2)" "unprognostic (3.38e-1)" "unprognostic (4.97e-2)" "unprognostic (5.04e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-2)" "unprognostic (8.21e-2)" "prognostic favorable (1.96e-8)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (4.27e-1)" "unprognostic (2.81e-1)" 13.4 13.3 8.7 5.7 11.6 10.8 11.5 8.4 12.8 7.7 1.4 10.0 6.0 7.9 8.8 12.3 7.4 6.8 19.7 9.4 9.9 14.0 16.4 8.4 7.6 11.6 13.7 7.5 11.8 14.8 7.8 9.2 12.1 8.2 10.3 43.8 10.0 6.8 59.6 14.1 7.8 7.6 9.2 6.4 9.5 10.7 9.7 9.2 9.6 40.5 8.7 10.3 8.7 9.4 16.2 6.1 10.6 11.1 19.6 18.8 17.2 11.4 21.3 17.1 19.8 8.3 11.7 14.6 7.5 15.4 13.9 21.3 12.6 18.4 20.9 12.2 12.3 14.5 7.5 6.1 22.3 21.3 10.0 14.5 21.1 14.0 40.1 24.2 14.7 11.3 34.5 15.2 18.9 11.6 11.7 8.9 10.7 26.8 9.7 10.9 20.7 5.3 20.1 12.4 15.6 11.5 16.4 15.6 31.0 38.0 11.9 18.0 17.2 9.9 5.0 15.3 10.5 11.9 10.5 14.7 14.9 16.1 16.4 5.1 9.5 2.3 2.3 8.0 2.8 3.1 3.1 2.7 5.4 3.2 2.8 2.3 3.6 6.5 6.4 2.9 4.5 4.7 8.7 11.6 8.4 12.8 9.4 9.9 11.6 13.7 12.1 9.2 9.7 9.4 18.7 22.4 16.7 32.3 21.5 24.6 33.6 22.7 30.1 180.5 21.8 22.4 42.7 12.8 25.3 18.4 12.5 48.5 19.7 31.7 52.8 29.1 34.8 17.7 16.0 17.5 23.4 19.8 41.9 31.6 35.0 20.0 13.3 23.5 8.8 19.7 15.7 36.0 26.0 48.8 38.1 25.4 18.3 30.8 19.8 15.5 14.0 26.3 16.0 27.2 54.7 57.9 12.3 27.6 45.4 36.4 17.8 15.4 15.4 40.3 32.6 44.4 19.6 35.2 0.0 21.3 15.6 33.1 22.6 32.1 27.1 95.9 19.3 22.9 24.0 43.1 BID ENSG00000015475 "BH3 interacting domain death agonist" P55957 22 17734138-17774770 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 103.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 273.2;Langerhans cells: 658.8;monocytes: 491.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "dendritic cells: 345.8;granulocytes: 925.5;monocytes: 985.3" "Cell line enhanced" "Detected in all" "MCF7: 241.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000722, CAB003771" Enhanced Supported Cytosol NA NA 800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" Cytosol "CAB003771: AB_365478, HPA000722: AB_1078283" "unprognostic (1.59e-1)" "unprognostic (5.51e-2)" "unprognostic (5.02e-2)" "unprognostic (3.04e-2)" "unprognostic (4.27e-3)" "unprognostic (1.11e-2)" "unprognostic (3.84e-2)" "unprognostic (5.21e-3)" "unprognostic (1.44e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-13)" "unprognostic (4.66e-3)" "unprognostic (1.59e-1)" "unprognostic (3.55e-3)" "unprognostic (2.18e-2)" 13.6 6.9 19.4 30.5 20.9 103.5 10.7 19.2 22.4 6.0 12.8 14.7 15.1 5.7 7.2 7.5 6.2 14.7 17.4 20.0 19.5 10.0 28.2 12.0 35.6 19.9 19.8 5.7 9.5 3.5 6.4 7.9 20.8 8.1 11.0 36.9 8.1 4.1 23.3 7.6 17.5 6.8 20.1 30.0 12.2 3.6 22.0 26.4 5.8 7.8 16.7 34.4 7.5 20.2 117.5 90.6 14.4 43.7 15.2 27.7 20.4 59.1 45.4 44.8 38.4 55.4 67.2 22.8 41.5 25.7 52.3 97.8 14.5 14.7 24.7 37.0 73.4 101.3 39.7 81.3 19.1 110.4 107.0 26.7 31.4 49.8 11.3 35.6 46.8 64.8 84.0 27.2 23.0 241.6 161.0 148.2 47.2 130.2 62.8 76.6 37.3 32.8 12.0 141.2 91.3 65.9 12.5 38.2 37.1 6.2 80.3 132.9 80.4 26.0 36.0 43.9 46.7 39.8 57.2 75.7 74.6 113.0 33.8 156.9 417.0 691.4 82.1 748.3 81.7 53.0 75.8 92.5 345.8 33.0 61.2 72.2 925.5 124.1 985.3 245.8 108.0 428.1 19.4 20.9 19.2 22.4 20.0 19.5 19.9 19.8 20.8 20.1 22.0 20.2 49.0 16.0 14.5 16.0 34.5 71.9 53.1 273.2 21.1 3.0 30.0 30.5 17.5 17.2 142.6 9.2 2.1 9.3 70.3 25.1 7.9 67.9 0.6 10.5 14.5 47.4 34.1 23.3 17.6 51.4 5.6 24.9 13.7 11.4 25.3 34.3 23.2 44.0 134.1 0.0 15.6 38.7 63.1 69.1 658.8 1.6 5.3 164.2 58.7 13.1 491.3 3.0 65.9 4.5 2.1 78.5 85.1 4.1 45.2 186.4 16.5 28.6 59.7 1.7 0.0 12.0 24.3 1.3 11.9 13.2 64.5 5.1 38.3 13.6 49.8 213.0 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 PEX26 FLJ20695 ENSG00000215193 "Peroxisomal biogenesis factor 26" Q7Z412 22 18077923-18105396 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 198.7;Proximal enterocytes: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB070429 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB070429: AB_11154363" "unprognostic (2.25e-1)" "unprognostic (5.75e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.77e-3)" "unprognostic (5.46e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.10e-4)" "unprognostic (1.59e-2)" "unprognostic (5.34e-2)" "unprognostic (8.19e-2)" "unprognostic (1.88e-2)" "unprognostic (1.96e-1)" "prognostic favorable (1.38e-4)" "unprognostic (3.17e-3)" "unprognostic (4.53e-2)" "unprognostic (1.37e-1)" "unprognostic (2.49e-1)" 7.5 5.8 7.3 7.8 6.2 12.1 6.7 3.7 6.8 4.9 5.8 16.9 19.2 5.5 5.3 7.5 6.0 5.3 5.8 7.9 5.3 7.5 7.3 5.0 7.3 8.4 7.8 5.4 8.0 9.2 4.2 5.0 7.0 5.3 13.1 3.1 6.4 5.6 6.3 5.6 19.9 5.4 6.3 8.1 9.3 3.1 8.3 7.3 6.9 4.1 6.7 6.0 3.9 5.5 18.3 8.7 10.2 9.2 10.5 6.6 18.8 11.8 12.2 12.8 10.5 15.2 15.1 11.3 10.8 17.5 11.2 18.7 15.9 16.5 10.9 19.0 12.4 19.4 12.3 12.8 10.0 26.0 23.6 8.2 12.7 17.3 16.2 6.1 15.2 11.1 21.2 8.1 12.7 22.0 22.8 8.8 13.2 24.9 15.7 17.6 8.6 4.1 14.8 20.6 17.7 15.5 17.1 12.0 16.3 8.2 19.3 9.7 20.4 23.6 10.2 12.8 12.4 21.4 15.8 16.6 10.9 12.3 17.1 1.2 1.7 1.4 2.0 1.1 1.9 1.4 1.8 2.6 1.5 2.0 2.0 1.3 1.2 2.7 2.6 3.1 0.8 1.0 7.3 6.2 3.7 6.8 7.9 5.3 8.4 7.8 7.0 6.3 8.3 5.5 10.5 6.4 10.3 1.3 14.7 13.5 14.8 9.3 8.6 24.5 12.4 7.2 29.3 25.8 13.8 7.3 43.8 11.9 18.0 198.7 5.9 24.7 1.0 16.3 16.2 17.6 24.5 11.1 4.9 23.6 9.8 13.0 20.9 18.6 12.0 19.8 18.9 33.0 15.2 30.3 5.6 22.9 6.1 20.4 10.7 2.8 12.5 11.0 0.0 2.8 20.4 9.2 22.6 4.5 4.3 31.6 51.8 11.7 11.8 20.4 91.7 21.7 11.5 25.5 13.1 18.8 9.6 9.4 10.1 13.7 17.6 9.3 13.9 21.4 29.4 18.7 TUBA8 TUBAL2 ENSG00000183785 "Tubulin alpha 8" Q9NY65 22 18110100-18146683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 128.9;skeletal muscle: 332.2;tongue: 154.7" "Cell type enhanced" "Detected in some" "Early spermatids: 16.4;Excitatory neurons: 8.1;Inhibitory neurons: 5.6;Late spermatids: 22.9;Sertoli cells: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 2.8;eosinophil: 2.7;neutrophil: 5.0;NK-cell: 10.4" "Group enriched" "Detected in many" 7 "granulocytes: 5.0;NK-cells: 10.4" "Group enriched" "Detected in many" 5 "NB-4: 30.2;SCLC-21H: 10.9;TIME: 36.3" "Group enriched" "Detected in all" 4 "cerebellum: 54.7;olfactory bulb: 53.9" "Low region specificity" "Detected in all" "HPA043684, CAB046031, HPA063394" Approved Supported Microtubules NA NA 80000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 24: NB-4 - Immune response" "Cluster 34: Spermatids - Unknown function" Microtubules "CAB046031: AB_11124541, HPA043684: AB_2678617, HPA063394: AB_2685003" "unprognostic (1.07e-1)" "unprognostic (1.34e-2)" "unprognostic (2.79e-3)" "unprognostic (1.52e-2)" "unprognostic (2.74e-1)" "unprognostic (8.92e-2)" "unprognostic (6.88e-2)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-2)" "unprognostic (3.36e-1)" "unprognostic (2.90e-5)" "unprognostic (9.12e-2)" "unprognostic (6.05e-2)" "unprognostic (4.08e-2)" "unprognostic (5.61e-4)" 7.3 1.9 9.0 1.0 11.8 4.7 7.2 24.3 16.3 2.5 0.8 2.0 0.8 2.7 6.3 4.3 4.8 1.0 128.9 15.0 2.8 2.3 4.3 2.4 3.5 0.6 9.0 2.3 4.4 2.7 14.5 0.6 0.8 2.5 0.5 2.8 4.4 0.6 332.2 4.4 2.6 0.7 1.5 4.2 4.7 52.3 11.5 0.8 6.5 154.7 1.0 2.0 2.2 12.5 0.6 1.1 1.2 1.4 1.8 0.5 0.4 0.6 0.3 1.4 0.8 0.9 1.1 0.9 2.2 0.7 0.4 0.6 2.2 0.4 0.3 0.8 1.6 2.2 1.7 0.9 1.0 1.0 1.0 0.7 0.8 0.8 0.6 0.5 2.0 0.9 0.6 0.9 0.6 3.4 1.0 30.2 1.0 0.5 0.5 0.9 0.5 0.2 0.7 1.1 10.9 1.1 0.6 1.9 1.0 0.5 0.6 4.8 36.3 0.9 1.0 1.0 0.4 2.2 1.3 0.7 0.9 1.4 0.6 2.8 0.7 2.7 0.5 0.6 0.7 0.4 0.4 0.3 0.4 0.6 0.7 0.4 5.0 10.4 0.4 1.0 0.8 17.1 9.0 11.8 24.3 16.3 15.0 2.8 0.6 9.0 0.8 1.5 11.5 12.5 0.2 0.0 1.7 1.6 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.3 4.7 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.3 16.4 0.2 0.1 0.4 0.0 0.0 8.1 1.1 0.0 0.3 0.0 0.2 2.5 0.1 0.7 0.0 0.1 3.3 5.6 0.0 0.0 0.3 0.0 22.9 0.3 0.1 0.0 0.0 0.2 0.1 1.0 3.5 1.7 0.6 0.1 0.4 0.0 0.0 0.4 0.1 0.0 0.2 6.6 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.0 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150170-18177397 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Extravillous trophoblasts: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 181.8;BJ hTERT+ SV40 Large T+ RasG12V: 196.2" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Vesicles "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 10.8 5.0 3.6 5.1 3.8 8.1 8.3 3.3 4.5 4.0 4.0 5.0 6.0 3.2 7.8 4.0 7.3 6.6 4.4 3.7 3.9 5.9 23.6 7.9 9.2 5.1 3.9 2.9 4.2 3.6 5.7 5.7 4.2 5.3 4.4 0.7 14.0 2.5 3.8 3.4 6.7 4.0 7.0 11.0 7.2 9.7 4.1 15.0 7.3 5.5 6.5 4.0 3.6 3.7 14.4 14.6 4.2 18.2 18.2 13.5 18.4 7.3 17.5 181.8 196.2 2.2 20.1 0.2 10.8 4.0 57.5 4.9 21.6 6.4 6.2 64.4 29.4 28.3 1.9 27.0 2.1 6.9 25.7 6.0 2.5 12.8 0.0 1.0 40.8 20.6 1.4 1.7 1.8 24.9 33.4 16.7 12.7 15.6 11.0 13.1 28.4 0.0 3.6 12.4 15.2 11.9 8.8 15.0 71.9 16.3 9.9 6.6 66.7 1.3 3.5 4.1 7.5 3.4 45.4 0.2 16.3 17.1 10.5 3.2 3.9 8.3 8.5 11.0 10.7 5.3 7.2 11.1 1.8 3.4 8.2 9.6 0.7 13.3 8.6 3.3 13.1 5.3 3.6 3.8 3.3 4.5 3.7 3.9 5.1 3.9 4.2 7.0 4.1 3.7 9.7 9.6 4.8 0.7 2.5 1.7 4.5 5.7 2.2 0.2 8.4 8.3 1.4 8.6 6.9 0.0 0.0 4.6 3.0 6.2 46.9 5.9 1.6 20.1 2.5 8.4 3.0 1.3 0.5 11.1 31.9 7.1 4.1 6.3 0.0 8.5 11.0 5.5 8.7 0.0 0.6 3.5 6.1 6.3 0.8 1.7 3.7 3.8 3.6 0.0 1.6 5.1 8.2 2.0 0.3 13.4 3.2 7.2 2.3 2.5 5.4 8.0 12.2 0.3 6.6 8.0 2.5 10.9 1.0 4.0 1.0 1.5 5.0 5.5 2.8 2.9 GGTLC3 ENSG00000274252 "Gamma-glutamyltransferase light chain family member 3" B5MD39 22 18516344-18518161 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 10.5;thyroid gland: 8.2" "Group enriched" "Detected in some" 10 "Alveolar cells type 1: 3.2;Early spermatids: 5.3;Late spermatids: 12.1;Spermatocytes: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SuSa: 1.5;U-2197: 1.0" "HPA045635, HPA047534" Uncertain NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (1.37e-1)" "unprognostic (2.06e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.3 0.5 0.1 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 10.5 0.1 2.2 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.6 0.4 0.0 0.1 0.0 0.2 2.3 0.1 0.0 8.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM191B ENSG00000278558 "Transmembrane protein 191B" P0C7N4 22 18527802-18530573 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 55 "testis: 93.1" "Group enriched" "Detected in many" 8 "Early spermatids: 425.9;Late spermatids: 489.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 1.0;CACO-2: 1.2;U-266/70: 1.1" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (1.70e-1)" "unprognostic (8.90e-2)" "unprognostic (3.18e-1)" "unprognostic (9.75e-2)" "unprognostic (1.60e-1)" "unprognostic (3.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.27e-1)" "unprognostic (1.98e-1)" "unprognostic (6.25e-2)" "unprognostic (4.90e-2)" "unprognostic (4.65e-2)" "unprognostic (4.44e-2)" "unprognostic (2.10e-2)" "unprognostic (3.54e-1)" "unprognostic (9.40e-2)" "unprognostic (9.22e-2)" 0.3 0.3 0.5 0.1 0.6 0.1 0.4 0.1 1.0 0.4 0.0 0.4 0.7 0.1 0.0 0.9 0.7 0.0 0.2 0.5 0.3 0.9 0.7 0.6 0.0 1.1 0.2 0.2 0.2 0.1 1.6 0.1 0.6 0.4 0.0 0.0 0.4 0.0 0.1 0.7 0.5 0.0 0.1 1.1 0.4 93.1 0.4 0.0 1.0 0.0 0.0 0.2 0.5 0.4 0.4 0.0 0.3 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 1.2 0.2 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.2 0.4 0.7 0.0 0.2 1.7 1.1 0.6 0.6 2.6 0.3 0.3 0.9 0.6 1.1 0.6 0.7 1.2 0.9 0.3 2.2 1.0 0.6 1.3 0.5 0.6 0.1 1.0 0.5 0.3 1.1 0.2 0.6 0.1 0.4 0.4 1.4 0.0 0.5 1.0 6.0 0.0 4.4 0.0 3.4 2.7 12.0 16.3 0.9 5.7 0.0 9.2 0.0 28.9 13.1 16.2 3.9 8.4 425.9 4.3 0.3 1.3 10.9 0.0 3.9 8.0 11.7 2.0 2.0 2.7 0.0 0.7 1.1 8.0 8.6 1.7 4.0 14.8 0.0 6.6 0.0 489.3 2.5 6.8 0.0 0.0 12.9 2.1 26.8 0.5 0.9 34.7 5.9 2.2 2.0 5.8 55.9 11.9 0.0 2.7 0.0 1.1 3.0 7.7 5.2 7.3 0.0 10.9 7.6 2.9 11.5 3.4 RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "brain: 35.7;choroid plexus: 24.5;testis: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 3.0;THP-1: 3.2" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.29e-2)" "unprognostic (9.81e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" "unprognostic (6.06e-3)" "unprognostic (9.58e-2)" "unprognostic (8.49e-3)" "unprognostic (7.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.69e-3)" "unprognostic (7.95e-2)" 0.1 0.2 7.9 0.4 10.8 0.1 0.0 35.7 22.0 0.1 24.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 11.0 11.7 0.0 0.0 0.2 0.8 14.9 10.1 0.1 0.1 0.3 0.1 0.2 26.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 19.6 0.7 0.2 28.4 13.5 1.0 0.4 0.0 0.5 0.0 0.0 32.4 0.4 1.3 0.5 0.4 0.7 0.3 0.0 0.5 1.4 0.6 0.7 0.0 0.0 0.3 0.6 0.2 0.4 0.3 0.3 0.0 0.1 1.4 0.4 0.6 0.3 0.5 0.0 2.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.2 0.3 0.5 0.6 3.0 1.7 0.6 0.6 0.1 1.2 1.6 0.2 0.1 0.1 0.8 0.1 1.2 0.0 0.2 0.1 0.1 3.2 0.1 1.0 0.7 0.5 0.3 0.0 0.4 0.3 0.5 0.7 1.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.3 7.9 10.8 35.7 22.0 11.0 11.7 14.9 10.1 26.2 19.6 13.5 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM246B ENSG00000286175 "Family with sequence similarity 246 member B" A0A494C0N9 22 18633984-18634682 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DGCR6 ENSG00000183628 "DiGeorge syndrome critical region gene 6" Q14129 22 18906028-18914238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 63.8;skeletal muscle: 183.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1045.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.3" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 8 "OE19: 46.5" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (9.80e-3)" "unprognostic (2.12e-3)" "unprognostic (1.51e-1)" "unprognostic (3.93e-3)" "unprognostic (2.41e-1)" "unprognostic (3.14e-1)" "unprognostic (1.60e-1)" "unprognostic (1.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (5.77e-2)" "unprognostic (2.23e-2)" "unprognostic (3.38e-2)" "unprognostic (8.08e-2)" "unprognostic (3.11e-1)" "unprognostic (1.28e-1)" 15.9 10.0 6.6 0.7 6.5 2.0 15.0 8.7 7.3 6.5 8.3 3.9 1.4 2.1 2.3 7.3 4.0 1.1 63.8 6.5 6.6 11.0 27.1 9.6 1.7 7.4 6.2 2.2 13.1 1.7 19.9 1.3 7.5 6.9 0.9 4.5 12.6 1.5 183.4 26.3 5.0 0.8 5.3 4.2 5.5 26.2 7.1 1.4 21.9 7.0 1.4 4.7 7.9 7.4 0.7 2.5 3.8 2.9 1.7 1.5 0.8 0.9 0.8 1.4 0.9 0.6 1.5 0.3 1.2 1.4 0.8 1.7 2.9 1.5 1.0 1.2 5.6 0.6 3.1 0.6 1.2 1.5 0.5 1.0 2.1 1.1 0.4 1.2 0.6 1.9 3.9 1.8 1.3 1.7 1.3 2.2 1.5 46.5 1.7 2.2 3.3 0.2 0.7 0.2 3.5 1.7 1.2 0.5 0.5 2.8 1.9 0.3 0.3 2.5 2.1 0.7 0.7 1.8 0.3 0.4 1.6 2.5 1.8 10.3 1.1 1.9 0.4 1.8 1.1 0.3 1.2 1.0 3.0 0.1 1.8 1.5 0.4 0.4 1.1 0.2 1.2 2.4 6.6 6.5 8.7 7.3 6.5 6.6 7.4 6.2 7.5 5.3 7.1 7.4 3.8 9.6 5.1 17.3 1.4 16.4 10.2 19.6 0.0 6.0 6.9 17.8 60.4 7.2 15.2 7.3 4.2 2.3 2.0 1.5 23.5 1.3 245.4 3.8 1.8 3.9 1.8 0.0 6.3 2.6 2.7 8.9 0.5 1.1 8.9 0.6 1.8 16.3 2.6 30.3 5.4 3.9 14.2 4.6 16.3 1045.2 4.4 2.3 80.0 3.7 2.5 11.3 0.0 10.6 5.4 1.9 0.1 8.2 1.1 2.9 10.5 4.9 46.4 2.7 6.6 11.0 11.6 5.1 3.2 0.0 31.7 2.3 2.9 0.9 1.6 8.5 AC007326.4 ENSG00000283809 "Novel protein" 22 18906238-18947732 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HAP1: 350.1;NTERA-2: 114.2;SuSa: 77.0" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 35: Glandular cells - Unknown function" 9.8 8.9 28.1 9.2 27.9 13.0 9.8 35.5 33.0 3.4 30.0 5.0 15.2 7.1 16.5 4.2 5.1 6.0 7.1 27.7 30.0 16.1 6.7 8.2 12.9 29.4 26.9 7.4 5.5 4.2 0.1 7.2 29.2 6.8 5.3 41.9 10.3 5.4 17.2 17.2 15.3 4.7 24.3 14.0 8.2 11.3 29.2 8.5 10.1 3.6 6.3 3.6 0.0 37.4 13.0 11.7 8.5 11.8 6.7 8.6 51.6 9.3 3.3 3.2 3.8 10.5 24.9 7.7 17.9 6.6 11.3 11.1 350.1 5.6 4.5 36.7 7.7 6.3 28.3 9.9 6.1 8.0 7.8 7.1 8.2 7.2 2.9 8.8 1.8 14.8 11.3 13.1 3.6 12.0 11.8 8.2 114.2 7.8 8.9 14.2 6.4 15.2 8.8 9.3 14.0 9.8 9.1 7.5 41.0 77.0 12.9 6.8 9.7 12.1 13.0 8.5 7.1 12.0 6.9 10.2 15.7 10.8 6.8 9.3 14.7 7.0 10.1 13.2 7.1 5.8 7.3 7.7 8.6 8.9 8.4 10.2 19.2 7.7 8.9 3.9 6.6 7.0 28.1 27.9 35.5 33.0 27.7 30.0 29.4 26.9 29.2 24.3 29.2 37.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 49.2;skin 1: 39.8" "Cell type enriched" "Detected in some" 7 "Astrocytes: 183.1" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 91.3;RPTEC TERT1: 35.9" HPA020361 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" "unprognostic (2.46e-2)" "prognostic favorable (1.54e-4)" "unprognostic (1.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-2)" "unprognostic (6.56e-2)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.94e-2)" 7.9 0.7 5.8 0.4 6.4 0.0 8.5 3.1 9.0 5.0 34.0 3.1 5.6 1.5 0.1 11.6 5.8 0.1 18.6 6.5 2.8 16.7 15.6 20.6 0.2 7.3 4.7 0.5 1.4 0.0 5.4 0.2 2.5 3.2 0.3 0.6 4.2 0.2 49.2 39.8 32.5 0.0 3.3 0.5 3.5 1.7 7.6 0.3 7.4 6.2 0.8 4.2 8.5 3.4 0.0 0.8 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.0 0.0 2.9 3.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.9 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 4.5 91.3 0.0 0.0 0.0 0.4 35.9 0.9 0.1 0.2 0.8 1.4 0.3 5.2 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 6.4 3.1 9.0 6.5 2.8 7.3 4.7 2.5 3.3 7.6 3.4 0.1 16.0 25.6 183.1 0.0 5.1 0.3 13.1 0.0 0.0 0.2 0.1 1.8 0.0 11.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.6 1.2 0.2 0.4 3.5 0.0 0.5 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 2.0 0.0 1.5 0.1 0.0 0.1 21.4 17.8 0.0 0.6 0.0 14.1 2.1 0.0 2.3 0.0 0.0 0.0 8.0 0.1 21.0 0.1 0.0 1.1 0.6 0.2 0.4 1.0 15.2 0.0 0.3 0.0 1.6 0.2 DGCR2 "DGS-C, IDD, KIAA0163, LAN, SEZ-12" ENSG00000070413 "DiGeorge syndrome critical region gene 2" P98153 22 19036282-19122454 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000873 Uncertain NA NA 84000 "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA000873: AB_1847632" "unprognostic (1.68e-1)" "unprognostic (4.27e-2)" "unprognostic (4.03e-2)" "unprognostic (1.33e-2)" "unprognostic (6.28e-2)" "unprognostic (8.51e-2)" "unprognostic (1.05e-1)" "unprognostic (6.86e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-1)" "unprognostic (2.06e-2)" "prognostic favorable (8.72e-7)" "unprognostic (3.63e-2)" "unprognostic (2.29e-1)" "unprognostic (6.27e-2)" "unprognostic (6.28e-3)" 25.3 28.6 45.7 14.9 40.4 7.4 26.4 34.6 48.9 30.0 24.7 34.0 26.2 32.9 12.9 46.5 27.7 19.0 33.6 44.1 42.8 31.1 30.6 28.6 16.8 45.2 43.3 35.9 44.6 26.3 33.1 16.4 43.6 34.7 16.0 9.1 33.7 23.5 27.2 61.3 28.8 15.6 38.3 25.5 30.2 25.3 52.0 16.7 39.8 19.5 12.5 31.2 32.1 38.6 43.2 26.5 32.6 58.3 57.9 23.2 31.8 28.3 34.8 27.2 26.8 45.7 47.9 22.7 38.7 30.7 19.4 79.7 24.2 27.2 11.4 19.4 44.4 15.3 16.0 37.0 35.1 28.8 33.4 33.3 61.6 21.1 24.3 23.4 30.3 14.2 115.6 19.3 14.0 45.0 15.2 31.0 27.3 67.8 19.1 26.5 34.4 8.9 46.2 46.8 44.4 32.8 52.1 36.0 32.6 17.6 33.5 25.9 27.0 50.0 25.6 26.3 23.1 21.5 8.5 14.9 23.7 16.5 38.9 9.5 10.3 16.5 6.1 5.3 5.3 4.3 6.5 6.1 6.8 4.7 7.8 6.4 23.5 4.6 3.9 4.0 9.5 11.3 45.7 40.4 34.6 48.9 44.1 42.8 45.2 43.3 43.6 38.3 52.0 38.6 16.4 19.2 27.0 34.3 10.0 9.7 10.8 17.1 17.6 30.1 23.4 20.6 18.0 30.0 23.3 27.6 14.6 17.2 9.5 59.7 0.0 24.9 13.7 9.6 11.2 13.7 19.9 4.2 35.7 21.9 19.0 13.5 27.0 16.9 8.2 24.5 21.4 27.3 12.1 37.0 43.7 30.3 18.3 18.5 4.7 22.2 17.1 10.4 8.8 22.5 16.4 18.5 11.3 54.8 32.6 30.9 24.0 22.6 11.1 18.8 27.7 10.6 14.0 23.0 13.1 14.4 15.1 12.6 12.9 22.1 12.4 10.8 11.8 17.7 28.4 16.8 ESS2 "bis1, DGCR13, DGCR14, DGS-H, DGSI, ES2, Es2el, ESS-2" ENSG00000100056 "Ess-2 splicing factor homolog" Q96DF8 22 19130279-19144684 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 15.7;Distal tubular cells: 13.7;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 9.4;RH-30: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001221, HPA001222" Enhanced Approved Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "HPA001221: AB_1078645, HPA001222: AB_1078647" "unprognostic (8.31e-2)" "unprognostic (1.81e-3)" "unprognostic (2.26e-1)" "unprognostic (2.83e-1)" "unprognostic (5.75e-3)" "unprognostic (4.70e-2)" "unprognostic (2.43e-2)" "unprognostic (6.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.05e-1)" "unprognostic (1.70e-1)" "unprognostic (5.89e-2)" "unprognostic (9.36e-2)" "unprognostic (3.04e-2)" "unprognostic (1.71e-3)" 0.6 0.4 3.2 0.6 3.2 0.2 0.5 4.9 3.3 1.2 1.9 2.2 0.4 1.4 0.5 1.0 0.9 0.5 1.3 2.9 2.9 0.9 0.4 0.5 0.8 3.2 3.2 1.3 0.7 0.7 1.1 0.5 3.3 1.0 0.4 1.3 0.6 1.2 1.6 1.4 0.9 0.9 2.8 0.9 1.1 2.0 3.0 0.8 0.8 1.6 0.8 1.7 0.9 3.4 1.6 3.0 1.7 1.9 2.7 0.5 0.7 1.5 0.9 2.6 2.1 2.4 0.6 2.3 0.5 0.7 0.6 2.8 5.1 0.8 1.3 3.4 5.8 0.6 2.7 0.4 0.7 2.8 2.0 0.4 3.0 1.8 0.5 0.7 0.5 1.6 9.4 0.3 1.2 1.7 1.7 1.6 1.5 1.8 2.3 2.6 8.3 0.0 0.7 1.2 4.3 0.9 0.7 1.3 1.9 1.1 0.9 1.3 0.4 2.2 3.2 2.2 1.2 1.1 2.5 0.8 0.7 1.7 1.4 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.4 0.0 0.2 0.0 0.1 3.2 3.2 4.9 3.3 2.9 2.9 3.2 3.2 3.3 2.8 3.0 3.4 6.3 6.4 4.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 6.1 6.7 0.0 0.0 1.8 9.2 0.0 15.7 8.3 0.0 13.7 13.2 0.0 7.5 6.9 4.0 0.0 0.0 0.0 10.4 12.4 3.7 0.0 7.5 5.1 10.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 10.3 0.0 0.0 0.0 0.0 13.4 0.0 0.0 2.3 0.0 0.0 12.7 4.4 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 16.3 4.0 10.2 0.0 0.0 TSSK2 "FLJ38613, SPOGA2, STK22B" ENSG00000206203 "Testis specific serine kinase 2" Q96PF2 22 19131308-19132622 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 231 "testis: 135.9" "Group enriched" "Detected in some" 94 "Early spermatids: 1657.2;Late spermatids: 3184.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 135.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.7 0.4 0.0 0.1 0.1 0.6 0.2 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1657.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3184.4 18.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 25.7 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSC2 GSCL ENSG00000063515 "Goosecoid homeobox 2" O15499 22 19146993-19150292 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 1.2;retina: 1.1;testis: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "pons: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "THP-1: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA043011 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 43: THP-1 - Innate immune response" "HPA043011: AB_10959883" "unprognostic (3.29e-1)" "unprognostic (1.56e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC25A1 "CTP, SLC20A3" ENSG00000100075 "Solute carrier family 25 member 1" P53007 22 19175581-19178739 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 197.7" "Cell type enhanced" "Detected in all" "Hepatocytes: 221.1;Proximal enterocytes: 304.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 101.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "unprognostic (2.12e-1)" "unprognostic (3.98e-1)" "unprognostic (8.17e-2)" "unprognostic (1.13e-1)" "unprognostic (9.39e-2)" "unprognostic (2.61e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (5.74e-2)" "unprognostic (3.90e-2)" "unprognostic (5.72e-2)" "unprognostic (4.52e-2)" "unprognostic (1.84e-1)" "unprognostic (3.46e-2)" "unprognostic (6.14e-2)" "unprognostic (9.03e-2)" 113.3 76.3 45.8 22.3 46.9 14.2 90.3 49.5 58.6 43.5 47.6 63.9 114.1 40.0 16.2 59.2 34.7 21.5 27.3 41.5 65.8 86.8 197.7 33.6 21.4 61.0 58.3 43.6 54.8 33.1 39.3 27.4 73.0 53.9 33.9 5.6 39.5 30.0 17.3 49.1 92.4 21.0 49.4 31.4 52.9 36.3 51.8 16.3 46.1 7.7 25.5 43.9 40.8 55.2 111.9 114.3 85.9 73.6 209.1 102.5 91.2 77.5 96.9 65.7 90.4 136.4 77.2 66.9 38.8 110.5 70.5 95.4 82.9 138.1 37.2 59.6 164.1 35.5 97.7 278.4 148.2 67.3 107.5 145.1 81.7 75.7 58.4 73.3 62.8 53.4 184.6 61.9 74.7 288.1 37.0 80.8 57.5 173.5 70.0 70.4 44.6 29.9 196.2 135.8 55.5 71.2 83.1 163.0 48.6 52.6 122.6 171.7 63.6 80.3 69.3 62.0 53.2 78.2 39.9 35.4 82.5 31.5 41.4 11.6 15.7 101.9 16.6 17.9 10.6 33.3 18.7 18.2 13.7 43.5 16.7 14.3 8.1 13.7 23.8 10.5 19.6 10.6 45.8 46.9 49.5 58.6 41.5 65.8 61.0 58.3 73.0 49.4 51.8 55.2 18.5 9.6 18.9 10.7 35.0 22.0 27.2 21.6 31.9 7.8 44.2 41.9 7.2 38.6 17.0 33.1 2.1 135.6 18.4 178.6 50.9 33.5 30.5 41.4 37.0 16.8 41.0 21.7 5.2 45.6 139.5 27.1 50.4 83.7 2.5 67.5 21.4 221.1 47.5 13.5 6.1 107.3 28.5 30.5 18.2 98.8 28.9 32.6 28.4 2.8 29.6 27.7 16.5 3.0 10.1 39.7 128.1 29.3 38.7 28.7 304.3 127.3 11.1 4.2 13.1 14.5 37.8 15.3 29.5 60.5 30.4 127.7 24.6 55.7 108.3 30.4 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 HIRA "DGCR1, TUP1, TUPLE1" ENSG00000100084 "Histone cell cycle regulator" P54198 22 19330698-19447450 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.7;Inhibitory neurons: 51.1;Oligodendrocytes: 45.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB039243, CAB039244, HPA050714, HPA052902" Enhanced Enhanced Nucleoplasm NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "CAB039243: , CAB039244: , HPA050714: AB_2681219, HPA052902: AB_2681984" "unprognostic (1.32e-1)" "unprognostic (1.74e-3)" "unprognostic (2.45e-3)" "unprognostic (1.11e-1)" "unprognostic (4.59e-2)" "unprognostic (2.46e-1)" "unprognostic (2.42e-2)" "unprognostic (2.17e-2)" "unprognostic (2.50e-1)" "prognostic favorable (8.11e-4)" "prognostic favorable (3.97e-4)" "unprognostic (9.05e-2)" "prognostic favorable (5.18e-6)" "unprognostic (4.84e-2)" "unprognostic (8.57e-2)" "unprognostic (6.36e-2)" "unprognostic (1.32e-3)" 11.2 12.9 16.1 10.6 15.1 26.1 10.2 14.6 15.9 9.4 13.3 14.0 13.9 12.3 6.0 12.4 12.2 7.3 12.9 15.9 14.1 13.8 21.7 10.6 14.2 14.2 15.3 11.2 12.6 22.1 13.2 8.4 13.8 9.3 10.1 7.3 9.9 8.8 23.4 12.5 13.7 9.4 14.0 13.1 14.2 10.1 17.9 20.6 56.1 11.0 11.4 12.2 8.6 14.6 27.0 23.5 32.4 33.7 31.0 20.5 22.5 22.4 25.7 36.1 35.6 53.8 15.4 52.1 10.6 29.0 21.5 30.8 46.4 28.2 23.1 32.1 53.9 48.4 25.5 49.5 33.6 113.1 33.6 24.7 27.1 28.3 27.6 19.4 26.5 51.6 253.1 27.0 20.9 33.7 56.0 40.4 29.6 63.8 23.5 43.7 46.0 15.6 20.9 29.8 47.0 31.2 25.0 25.4 31.7 16.4 16.0 39.0 30.7 24.5 36.0 25.4 26.5 28.4 30.3 53.7 28.7 36.2 20.7 4.8 0.7 3.3 1.3 0.7 1.3 2.4 0.7 1.3 0.9 4.5 0.3 1.0 1.3 2.1 0.4 1.7 0.4 0.8 16.1 15.1 14.6 15.9 15.9 14.1 14.2 15.3 13.8 14.0 17.9 14.6 7.7 6.4 0.5 29.4 7.4 9.2 2.2 4.4 0.6 7.7 6.4 7.4 2.3 2.8 2.3 5.5 2.1 3.8 12.6 11.7 5.9 5.4 6.2 6.8 8.4 5.6 2.4 19.4 49.7 8.9 3.6 4.7 3.1 7.1 0.0 8.7 7.1 21.1 6.6 16.8 51.1 10.5 4.1 9.1 3.8 2.4 5.0 4.9 10.6 38.4 7.9 5.5 14.4 37.7 45.5 7.9 8.4 6.8 4.5 5.0 8.2 9.9 4.2 4.6 6.6 7.7 6.1 12.9 10.3 4.5 10.5 3.0 6.6 9.2 14.2 2.2 C22orf39 MGC74441 ENSG00000242259 "Chromosome 22 open reading frame 39" Q6P5X5 22 19351368-19447711 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 118.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073701 Approved "Endoplasmic reticulum" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum" "HPA073701: AB_2686627" "unprognostic (4.97e-2)" "unprognostic (2.67e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.27e-2)" "unprognostic (6.53e-2)" "unprognostic (5.07e-2)" "unprognostic (1.95e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (1.45e-3)" "unprognostic (5.34e-3)" "prognostic favorable (1.44e-4)" "unprognostic (6.51e-2)" "unprognostic (2.92e-1)" "unprognostic (1.32e-2)" "unprognostic (5.32e-2)" 25.2 22.9 35.2 8.9 34.3 13.7 22.0 34.7 49.6 22.0 33.8 38.1 10.5 22.2 11.2 15.4 22.3 7.7 47.2 34.2 33.2 26.5 18.0 17.8 12.8 35.6 34.8 19.8 26.3 22.6 24.3 10.4 36.3 26.2 11.8 23.9 16.4 13.6 118.6 19.3 19.7 11.3 35.0 21.0 23.5 16.7 35.9 16.2 27.9 44.8 12.4 26.9 17.8 34.4 20.7 7.1 16.3 11.5 17.5 15.4 12.1 5.9 5.7 13.7 15.8 11.3 4.8 15.8 6.8 6.4 8.2 17.3 16.3 10.9 14.7 17.3 66.7 20.1 19.2 26.5 17.1 30.8 19.5 12.9 17.6 7.3 19.9 14.7 14.0 33.6 60.6 21.5 9.0 10.1 24.0 27.3 7.2 42.4 18.2 25.8 23.9 11.5 18.4 12.1 24.8 12.4 11.8 8.3 23.9 14.9 11.4 18.4 13.4 9.9 18.6 7.0 9.1 29.4 12.6 22.8 11.6 14.7 9.4 36.4 29.6 72.0 23.0 33.8 21.9 27.8 25.7 19.7 26.1 27.9 25.9 21.4 43.0 31.1 30.3 38.8 35.3 26.7 35.2 34.3 34.7 49.6 34.2 33.2 35.6 34.8 36.3 35.0 35.9 34.4 41.6 22.4 40.4 10.1 39.5 24.3 28.4 58.8 23.3 28.7 42.8 44.3 94.1 27.1 50.8 36.8 16.7 54.6 50.8 44.3 107.6 40.4 21.5 36.0 20.8 29.7 45.1 41.2 13.9 77.9 47.9 31.2 35.7 26.4 26.6 25.9 36.0 35.3 65.4 18.5 17.3 44.4 52.9 38.0 33.5 12.7 35.1 32.8 39.2 5.6 59.6 52.3 60.8 10.1 14.5 58.7 42.0 33.8 37.6 34.6 69.0 67.2 46.1 20.4 46.0 31.9 36.9 54.8 57.6 37.8 32.5 50.3 34.9 33.1 55.9 31.2 MRPL40 "MRP-L22, NLVCF" ENSG00000185608 "Mitochondrial ribosomal protein L40" Q9NQ50 22 19432545-19436075 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006181 Uncertain Supported Nucleoli,Mitochondria NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoli "HPA006181: AB_1079411" "unprognostic (4.12e-2)" "prognostic favorable (7.57e-4)" "unprognostic (2.64e-2)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (4.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.60e-2)" "unprognostic (4.08e-2)" "unprognostic (1.19e-2)" "unprognostic (2.16e-1)" "unprognostic (1.18e-3)" "unprognostic (2.67e-2)" "unprognostic (1.75e-1)" "unprognostic (8.07e-2)" "unprognostic (2.29e-1)" "unprognostic (3.14e-2)" 39.4 54.4 59.9 26.1 61.6 28.3 47.6 63.9 79.7 50.0 60.3 33.6 26.1 31.3 77.4 35.6 54.8 31.5 100.7 59.0 62.3 69.1 118.8 28.9 35.5 62.5 60.6 44.5 57.1 85.0 11.2 30.7 62.5 46.4 35.9 35.0 72.1 43.0 135.8 29.2 24.7 32.6 63.6 27.1 33.8 31.4 61.7 29.7 79.0 142.0 40.9 36.4 7.0 65.0 84.8 83.8 26.9 64.0 111.5 98.8 45.4 62.1 95.6 116.9 133.6 105.5 49.0 73.2 71.0 93.7 67.8 82.9 118.8 141.2 122.6 69.8 129.7 72.8 76.0 184.4 158.1 117.7 46.1 102.3 123.6 101.1 179.8 77.3 95.6 35.0 265.8 91.2 127.5 106.9 44.9 77.6 22.7 190.2 100.3 49.7 110.6 44.2 135.9 67.9 45.6 48.3 100.7 94.0 159.7 60.2 80.2 52.9 60.6 118.6 127.3 41.6 64.0 78.1 115.7 147.6 79.2 71.6 99.5 45.1 88.3 76.6 71.7 108.9 82.7 162.7 72.4 74.6 100.1 155.6 85.9 75.6 10.4 90.5 90.2 106.5 91.9 103.5 59.9 61.6 63.9 79.7 59.0 62.3 62.5 60.6 62.5 63.6 61.7 65.0 43.3 44.8 35.3 8.8 53.8 40.4 73.3 181.9 52.3 31.0 59.4 85.9 86.1 71.4 106.6 47.8 12.5 129.6 42.9 35.2 260.3 83.8 114.9 104.4 61.9 40.3 34.9 27.1 3.6 97.9 128.9 55.9 32.1 46.1 33.7 44.2 40.0 146.3 135.6 21.9 5.8 47.8 91.6 43.6 40.0 152.4 72.4 42.9 85.4 4.7 73.9 120.4 37.0 3.5 12.0 73.9 48.6 72.2 92.6 53.6 89.8 254.9 163.5 50.3 46.0 53.9 74.3 82.9 72.1 64.8 38.5 62.9 35.1 103.8 49.3 52.2 UFD1 UFD1L ENSG00000070010 "Ubiquitin recognition factor in ER associated degradation 1" Q92890 22 19449911-19479202 "Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 121.1;Ductal cells: 115.7;Exocrine glandular cells: 142.2;Extravillous trophoblasts: 107.3;Pancreatic endocrine cells: 149.9;Syncytiotrophoblasts: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 782.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030286, HPA030287" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" Nucleoli "HPA030286: , HPA030287: AB_10601830" "unprognostic (2.52e-1)" "unprognostic (5.41e-2)" "unprognostic (1.95e-3)" "unprognostic (7.61e-2)" "unprognostic (3.50e-2)" "unprognostic (2.70e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (9.79e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-3)" "unprognostic (8.82e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (4.50e-8)" "unprognostic (1.45e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-2)" 43.8 39.8 23.6 36.8 26.3 64.8 37.8 27.6 29.8 33.9 25.7 42.5 32.1 46.8 54.4 48.4 31.4 29.3 44.8 24.6 28.6 36.7 51.9 37.2 43.4 28.9 26.7 31.8 39.3 44.7 31.7 35.3 29.5 32.1 38.4 21.7 38.1 30.1 98.3 42.5 35.7 39.5 27.2 38.6 40.8 53.3 27.1 61.6 34.9 42.5 47.5 40.2 37.0 29.7 187.5 132.4 110.6 168.5 89.0 62.0 86.0 150.2 148.8 202.9 187.1 147.8 78.8 129.2 114.1 126.7 93.3 157.5 131.5 132.1 175.1 239.8 138.0 136.5 88.3 119.4 84.4 218.6 177.7 57.4 133.0 173.2 84.4 59.1 164.7 67.9 782.0 240.5 125.1 268.5 142.0 133.4 79.8 232.2 111.9 170.1 262.0 50.1 126.6 172.5 90.5 102.2 118.2 126.0 123.3 114.2 75.9 103.5 180.9 169.6 230.8 143.2 164.1 102.9 221.7 168.8 142.5 110.3 158.6 150.9 90.6 158.1 107.0 140.3 103.7 87.7 122.5 112.4 81.0 82.6 104.6 102.9 167.1 105.7 140.7 113.1 224.5 129.5 23.6 26.3 27.6 29.8 24.6 28.6 28.9 26.7 29.5 27.2 27.1 29.7 68.3 25.6 34.5 0.0 16.4 0.0 0.0 0.0 0.0 0.0 39.7 55.2 0.0 0.0 16.7 27.6 0.0 121.1 44.9 0.0 84.1 115.7 0.0 43.1 36.9 32.6 0.0 0.0 0.0 142.2 107.3 25.4 0.0 44.9 27.8 36.0 0.0 0.0 88.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 149.9 0.0 0.0 7.5 0.0 0.0 81.0 27.7 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.0 170.3 26.3 61.5 0.0 0.0 CDC45 "CDC45L, CDC45L2" ENSG00000093009 "Cell division cycle 45" O75419 22 19479457-19520612 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;lymphoid tissue: 20.4;testis: 23.4" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Erythroid cells: 29.7;Spermatocytes: 72.3;Spermatogonia: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "K-562: 370.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000614, CAB009459" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Centrosome, Cytosol" "CAB009459: AB_2078507, HPA000614: AB_1078487" "unprognostic (5.56e-2)" "unprognostic (6.12e-3)" "unprognostic (1.17e-3)" "unprognostic (3.42e-3)" "unprognostic (3.57e-1)" "unprognostic (7.42e-2)" "prognostic unfavorable (6.95e-6)" "unprognostic (6.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (8.94e-4)" "unprognostic (7.28e-2)" "unprognostic (0.00e+0)" "unprognostic (7.62e-3)" "unprognostic (2.02e-1)" "unprognostic (8.52e-2)" "unprognostic (1.10e-1)" 0.5 0.5 0.7 6.2 0.5 25.4 1.5 0.2 0.2 1.1 0.4 4.6 3.5 0.9 0.3 5.3 0.4 0.5 0.3 0.2 0.4 0.3 1.2 0.9 11.3 0.5 0.4 0.2 0.2 0.2 0.1 3.2 0.5 0.4 6.0 0.1 0.9 0.2 0.1 3.3 3.1 1.8 0.2 2.8 2.6 23.4 1.1 20.4 0.3 0.0 11.8 1.9 1.7 0.3 57.4 42.2 56.4 42.9 2.0 5.6 24.4 65.4 31.6 75.5 75.5 35.8 30.5 62.2 23.2 21.0 28.9 51.9 58.2 45.9 59.5 72.3 96.3 82.8 50.1 41.3 3.1 125.0 43.7 1.3 2.4 57.9 26.0 7.0 38.8 63.0 370.6 73.3 44.8 77.2 98.1 56.5 16.7 106.2 34.4 77.1 95.5 26.5 16.9 49.3 72.1 37.0 38.1 40.0 12.0 21.7 26.2 51.0 15.0 60.0 91.6 46.0 62.8 24.6 46.8 67.5 30.1 58.9 82.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.2 0.1 0.5 0.5 0.1 0.3 0.9 0.6 0.7 0.5 0.2 0.2 0.2 0.4 0.5 0.4 0.5 0.2 1.1 0.3 0.2 0.0 0.0 0.0 1.9 2.7 1.7 3.7 0.0 0.0 0.7 0.8 0.4 0.0 0.5 0.0 0.0 11.9 1.4 1.9 0.0 0.8 120.5 0.9 0.7 1.2 0.0 29.7 0.1 0.0 19.8 2.3 1.5 1.0 0.0 5.5 3.6 0.0 7.2 0.0 0.1 1.2 4.1 0.6 1.0 14.4 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.7 12.6 0.2 0.4 0.0 0.3 0.0 6.6 1.5 13.9 72.3 50.7 3.3 1.8 4.9 1.2 0.8 5.1 2.5 CLDN5 "AWAL, BEC1, CPETRL1, TMVCF" ENSG00000184113 "Claudin 5" O00501 22 19523024-19527545 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 439.7;breast: 420.9;lung: 398.7" "Group enriched" "Detected in many" 10 "Adipocytes: 2644.3;Endothelial cells: 775.2;Hepatic stellate cells: 701.4" "Cancer enriched" "Detected in all" 4 "glioma: 32.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 18.8" "Lineage enriched" "Detected in many" 4 "granulocytes: 18.8" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 85.4;SCLC-21H: 53.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002607 Approved NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB002607: " "unprognostic (1.26e-1)" "unprognostic (2.05e-3)" "unprognostic (1.77e-2)" "unprognostic (2.07e-1)" "unprognostic (3.05e-3)" "unprognostic (6.00e-2)" "unprognostic (4.98e-2)" "unprognostic (3.24e-3)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.29e-3)" "unprognostic (1.15e-1)" "unprognostic (7.31e-2)" "unprognostic (2.01e-2)" "unprognostic (2.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.96e-2)" 439.7 16.2 124.1 6.1 101.0 0.3 420.9 111.7 127.4 70.2 205.2 75.9 9.2 86.1 3.0 54.4 83.1 6.5 138.3 93.8 103.3 45.5 16.9 398.7 9.6 124.5 114.0 36.4 20.7 1.5 16.9 12.5 127.8 50.2 3.6 2.0 36.0 3.5 101.6 95.9 71.0 6.4 109.2 44.8 41.4 10.5 160.7 1.8 122.5 14.9 2.2 103.7 75.9 107.4 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.1 0.1 0.2 1.1 0.0 0.0 0.0 0.0 85.4 0.1 0.7 0.2 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.9 0.7 0.1 0.0 0.0 53.0 0.3 0.0 0.0 0.0 0.0 0.4 0.2 7.1 0.1 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.2 18.8 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 4.6 0.2 5.8 0.0 0.1 0.1 0.0 26.9 124.1 101.0 111.7 127.4 93.8 103.3 124.5 114.0 127.8 109.2 160.7 107.4 2644.3 3.2 7.7 0.7 2.4 32.4 1.1 0.1 3.4 1.8 5.9 7.6 14.8 2.8 0.6 7.3 0.0 0.3 4.2 0.0 0.0 0.7 5.0 8.1 0.7 775.2 2.4 8.0 0.0 0.8 0.1 12.5 0.0 1.0 1.3 0.3 701.4 2.7 0.8 0.0 0.1 0.2 4.1 17.0 33.3 5.5 5.3 46.2 14.2 129.3 0.7 2.4 1.0 0.5 0.3 0.0 0.0 0.7 2.8 4.0 0.0 0.0 0.3 7.3 0.0 61.7 12.1 1.1 1.9 1.2 30.5 0.0 4.6 25.0 0.0 6.7 SEPTIN5 "H5, HCDCREL-1, PNUTL1, SEPT5" ENSG00000184702 "Septin 5" Q99719 22 19714503-19724224 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 321.9" "Group enriched" "Detected in some" 9 "Cardiomyocytes: 3.4;Smooth muscle cells: 2.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 32 "eosinophil: 15.4;neutrophil: 5.8" "Lineage enriched" "Detected in single" 47 "granulocytes: 15.4" "Cell line enhanced" "Detected in many" "K-562: 281.6;THP-1: 75.9" "CAB016120, HPA029095, HPA063885" Enhanced Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA 860000 "Cluster 49: Eosinophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nucleoplasm, Actin filaments, Cytosol" "CAB016120: AB_628240, HPA029095: AB_2672904, HPA063885: AB_2685141" "unprognostic (4.07e-2)" "unprognostic (1.47e-1)" "unprognostic (6.78e-3)" "unprognostic (1.39e-2)" "unprognostic (3.92e-1)" "unprognostic (1.86e-1)" "unprognostic (2.50e-2)" "unprognostic (3.77e-1)" "unprognostic (5.66e-2)" "unprognostic (6.19e-2)" "unprognostic (1.88e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (6.87e-6)" "unprognostic (3.39e-2)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" "unprognostic (3.30e-2)" 17.7 17.7 152.8 5.7 215.6 41.0 16.4 49.2 321.9 54.1 61.9 19.8 5.2 28.1 46.2 62.1 38.8 14.7 165.4 233.6 49.3 12.7 5.2 17.4 8.4 40.9 45.2 29.3 17.0 127.3 82.7 12.0 39.4 20.1 6.3 30.3 15.9 9.9 10.8 126.5 8.8 17.3 24.7 14.3 16.3 29.1 73.1 15.9 33.4 16.2 8.1 13.5 42.8 168.6 0.4 10.6 42.0 64.0 3.9 13.1 0.3 15.8 20.1 17.9 10.5 0.7 5.6 1.5 6.1 35.8 26.0 6.0 30.2 6.0 8.8 9.6 3.4 0.7 2.4 0.2 16.2 0.8 47.2 17.4 7.4 6.0 2.5 5.1 7.5 23.1 281.6 0.6 28.2 4.2 4.6 31.2 5.4 1.0 10.4 41.4 1.3 7.2 1.3 1.4 62.3 49.2 2.4 3.5 2.8 10.2 17.3 75.9 3.0 46.4 55.6 2.0 3.2 4.5 0.0 0.4 5.8 2.2 15.2 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 5.8 0.0 0.0 0.3 0.0 6.0 152.8 215.6 49.2 321.9 233.6 49.3 40.9 45.2 39.4 24.7 73.1 168.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GP1BB "CD42c, GPIbbeta" ENSG00000203618 "Glycoprotein Ib platelet subunit beta" P13224 22 19723539-19724771 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;heart muscle: 27.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 74.0;neutrophil: 74.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 74.5" "Cell line enriched" "Detected in some" 4 "K-562: 85.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA 4400000 "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" 2.7 2.0 39.0 0.2 40.1 2.7 2.5 26.1 51.0 9.2 11.1 2.9 0.0 4.8 0.0 11.2 4.4 0.0 27.1 53.2 18.3 2.9 1.2 4.1 0.2 16.2 15.4 6.3 2.2 2.5 22.1 0.2 15.6 3.4 0.0 0.6 2.4 0.0 1.4 24.4 1.4 0.1 7.9 10.1 2.3 4.2 28.0 0.1 3.1 0.5 0.1 1.6 7.2 22.9 0.0 1.1 1.6 0.7 0.0 0.0 0.2 1.5 0.0 0.1 0.4 0.0 0.1 0.2 0.3 0.0 0.3 0.8 0.1 0.1 0.0 0.0 7.7 4.1 0.1 0.0 0.0 0.0 10.3 0.2 0.1 0.3 0.0 0.0 0.0 0.2 85.4 0.1 0.5 0.1 0.3 19.2 0.4 0.1 2.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.9 1.3 0.2 0.0 2.9 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 74.0 8.5 12.5 1.6 3.1 0.8 0.5 0.5 0.2 3.6 0.9 1.0 0.8 74.5 1.1 0.6 12.6 2.2 417.7 39.0 40.1 26.1 51.0 53.2 18.3 16.2 15.4 15.6 7.9 28.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBX1 "CATCH22, VCF" ENSG00000184058 "T-box transcription factor 1" O43435 22 19756703-19783593 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 61.5;tongue: 36.5" "Cell type enriched" "Detected in many" 4 "Late spermatids: 181.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 24.6;K-562: 121.6;NB-4: 28.6;TIME: 40.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA029330 Approved "Nuclear bodies,Cytoplasmic bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear bodies, Cytoplasmic bodies" "HPA029330: AB_2673002" "unprognostic (2.54e-1)" "unprognostic (4.28e-3)" "unprognostic (7.53e-3)" "unprognostic (1.59e-1)" "unprognostic (4.03e-2)" "unprognostic (2.63e-3)" "unprognostic (1.16e-1)" "unprognostic (2.53e-1)" "unprognostic (5.48e-2)" "unprognostic (1.18e-1)" "unprognostic (4.42e-2)" "unprognostic (2.25e-2)" "unprognostic (8.30e-3)" "unprognostic (9.14e-2)" "unprognostic (4.44e-1)" "unprognostic (8.31e-2)" "prognostic favorable (8.90e-4)" 4.0 0.6 0.5 1.0 0.7 0.1 8.0 0.6 0.8 7.4 0.8 1.8 0.7 2.6 0.2 3.0 7.7 0.4 0.8 0.2 0.2 0.4 0.4 4.3 2.9 0.6 0.2 2.2 0.3 7.6 0.7 0.1 0.5 5.2 0.3 0.0 8.1 0.5 61.5 10.6 3.0 0.6 0.0 0.6 1.2 16.8 0.9 0.0 11.2 36.5 1.2 2.7 7.1 1.0 15.3 1.4 0.2 10.7 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.1 0.1 0.3 0.3 0.3 1.5 0.8 12.0 10.4 0.0 0.6 24.6 0.2 2.9 0.0 0.0 0.1 0.1 0.1 0.1 2.4 0.0 0.0 0.0 0.5 121.6 0.0 7.7 2.8 0.3 28.6 1.7 0.0 16.8 0.3 10.6 0.1 0.0 0.0 1.5 0.4 0.0 0.2 0.0 3.1 5.1 7.7 40.0 0.1 0.4 0.2 0.2 0.3 0.5 0.1 0.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.6 0.8 0.2 0.2 0.6 0.2 0.5 0.0 0.9 1.0 11.4 0.0 2.8 0.0 0.3 2.4 1.6 3.3 0.0 0.6 1.1 0.9 2.4 0.0 1.6 0.0 0.0 0.2 0.6 0.1 0.0 0.0 43.3 0.2 0.1 7.5 0.0 0.0 0.3 0.2 1.7 1.5 0.0 0.2 2.5 0.1 2.5 0.0 2.0 0.0 0.9 1.0 6.1 1.3 3.6 181.9 2.5 1.0 0.0 0.0 0.1 0.3 2.1 0.0 0.0 0.1 0.0 2.2 0.0 1.0 0.1 0.0 2.3 0.1 0.0 1.1 0.8 1.9 12.8 0.3 2.4 0.1 0.7 0.0 0.2 2.0 GNB1L "GY2, WDR14" ENSG00000185838 "G protein subunit beta 1 like" Q9BYB4 22 19783223-19854939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 66.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034627, HPA034628" Approved Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA034627: AB_10600662, HPA034628: AB_10600440" "unprognostic (2.14e-1)" "unprognostic (5.56e-3)" "unprognostic (4.54e-3)" "unprognostic (2.58e-1)" "unprognostic (3.03e-1)" "unprognostic (3.34e-2)" "unprognostic (8.68e-4)" "unprognostic (1.09e-1)" "unprognostic (1.19e-1)" "unprognostic (4.26e-1)" "unprognostic (2.46e-1)" "unprognostic (2.99e-2)" "unprognostic (3.64e-5)" "unprognostic (9.80e-3)" "unprognostic (8.04e-2)" "unprognostic (2.88e-1)" "unprognostic (9.86e-2)" 3.5 2.2 1.4 2.8 1.8 1.7 3.5 1.0 3.7 3.8 0.6 4.0 4.1 4.1 0.4 4.9 3.9 1.0 2.7 1.8 0.8 2.6 2.8 3.1 2.3 1.3 0.7 3.5 3.9 0.4 2.2 1.4 0.9 3.4 0.3 0.3 3.3 1.3 3.7 5.9 3.7 0.6 0.6 5.3 2.7 2.4 0.9 4.0 3.0 0.6 1.3 4.2 4.2 1.3 13.5 10.2 2.9 8.9 0.9 1.7 8.0 9.1 2.5 4.4 4.1 18.3 5.2 18.1 5.8 2.1 2.1 25.5 2.0 4.3 0.6 11.7 34.0 10.9 13.6 9.1 2.7 12.6 2.9 1.4 2.0 3.9 1.5 1.0 1.7 8.1 66.6 6.8 0.8 19.3 28.1 18.1 5.0 3.9 17.1 14.6 8.1 4.1 0.4 5.4 5.9 6.4 3.5 8.8 15.5 0.5 2.3 3.2 4.2 9.8 11.8 16.1 9.3 8.8 7.8 9.6 10.6 11.1 3.4 7.3 6.0 15.9 13.2 7.9 12.7 9.4 12.6 10.0 9.8 11.9 12.1 11.0 6.1 12.0 5.9 13.3 17.0 7.5 1.4 1.8 1.0 3.7 1.8 0.8 1.3 0.7 0.9 0.6 0.9 1.3 2.4 3.2 4.4 3.6 6.9 22.0 6.3 11.8 5.2 8.5 4.7 5.5 1.6 2.8 5.7 0.0 12.5 15.2 5.2 4.6 3.9 5.6 28.3 2.9 3.3 4.6 0.0 4.0 6.7 3.3 13.8 4.3 2.0 4.1 12.7 7.8 2.2 2.8 10.3 0.0 4.1 4.6 8.2 7.3 15.5 6.5 3.4 4.6 14.2 1.9 4.9 3.0 6.2 4.5 4.3 5.9 2.6 4.9 5.4 8.8 6.3 4.9 1.9 4.7 6.6 2.8 4.4 13.8 10.2 5.1 16.2 4.7 7.9 2.7 5.2 5.3 RTL10 "BOP, C22orf29, FLJ21125" ENSG00000215012 "Retrotransposon Gag like 10" Q7L3V2 22 19846138-19854896 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Cytotrophoblasts: 20.6;Distal tubular cells: 13.7;Extravillous trophoblasts: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 95.9" "HPA000721, HPA001419" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" "HPA000721: AB_1079000, HPA001419: AB_1078999" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (3.70e-2)" "unprognostic (2.29e-2)" "unprognostic (4.72e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (8.04e-5)" "unprognostic (2.26e-2)" "unprognostic (2.36e-2)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "unprognostic (3.79e-2)" "unprognostic (6.67e-2)" "unprognostic (7.20e-3)" "unprognostic (3.34e-1)" "unprognostic (1.27e-1)" "unprognostic (7.55e-2)" 3.0 3.5 2.4 3.9 3.3 4.8 4.5 2.4 4.2 4.5 0.6 3.0 7.1 4.6 6.7 7.5 8.8 2.5 3.1 3.9 1.5 3.5 3.7 5.1 5.1 1.3 0.4 5.1 7.3 6.1 4.0 5.1 0.9 6.2 3.0 3.5 7.1 5.0 4.3 13.3 4.7 3.8 0.0 4.1 4.2 2.3 1.8 10.8 5.7 3.9 7.2 4.1 4.6 1.6 18.9 7.6 8.5 9.5 9.1 8.0 10.7 10.4 12.0 15.0 9.1 15.5 10.4 16.4 4.3 17.8 4.6 26.4 8.6 17.0 6.6 5.6 12.9 8.7 17.6 10.9 5.8 25.7 7.4 6.0 19.9 12.6 10.6 7.2 14.1 9.9 95.9 6.0 14.5 12.5 21.0 7.8 4.6 21.4 10.3 11.8 25.1 4.0 5.5 17.3 13.9 5.0 10.8 12.2 10.3 8.8 13.4 5.7 18.2 14.7 16.8 4.8 10.0 5.3 5.0 9.8 5.6 6.9 9.9 2.6 1.4 3.1 1.8 1.6 1.7 1.1 2.0 1.8 1.3 1.4 3.9 3.0 2.3 0.8 4.0 2.6 3.0 1.8 2.4 3.3 2.4 4.2 3.9 1.5 1.3 0.4 0.9 0.0 1.8 1.6 3.6 22.4 9.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.3 5.8 0.0 0.0 5.0 9.2 0.0 20.6 2.2 0.0 13.7 7.6 0.0 8.8 5.0 4.4 0.0 0.0 0.0 5.0 16.6 2.4 0.0 9.7 1.3 10.8 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.4 0.0 0.0 5.4 5.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 4.7 2.1 6.4 0.0 0.0 TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2 OS: 139.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 2800000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Mitochondria, Cytosol" "CAB002007: , HPA003323: AB_1080396" "unprognostic (3.17e-2)" "unprognostic (8.72e-2)" "unprognostic (4.30e-1)" "unprognostic (9.71e-3)" "unprognostic (7.25e-2)" "unprognostic (6.35e-2)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (2.83e-1)" "unprognostic (4.94e-3)" "unprognostic (2.49e-1)" "prognostic favorable (1.10e-7)" "unprognostic (2.47e-1)" "unprognostic (5.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" 10.5 44.4 11.9 8.9 12.0 14.5 12.3 18.1 19.3 11.7 21.2 14.9 10.3 10.6 6.2 10.2 10.6 6.2 30.0 12.9 11.9 24.8 65.4 13.6 9.1 11.8 12.1 16.5 15.9 13.5 14.4 9.8 11.5 26.8 4.6 4.4 15.4 8.2 23.0 10.9 12.0 5.1 11.3 16.9 26.4 14.6 12.4 4.9 15.2 16.1 6.1 11.8 10.4 11.8 19.4 39.2 3.5 14.9 6.9 9.6 8.8 18.8 21.1 31.8 23.4 36.7 19.4 10.9 43.2 19.0 32.7 33.2 17.8 25.2 12.1 21.6 46.5 18.8 34.4 22.4 12.9 21.1 8.4 9.2 18.5 16.2 13.8 12.9 91.3 2.2 106.4 17.4 24.8 47.1 7.2 30.1 17.7 46.9 27.6 10.5 85.2 10.0 19.3 21.0 19.1 16.4 32.0 39.9 21.8 5.8 33.7 27.6 52.2 23.0 139.5 19.8 38.4 17.6 14.0 6.9 22.4 15.5 30.3 2.7 10.5 5.8 3.5 8.2 2.6 3.9 3.0 3.2 7.8 2.6 3.9 3.2 0.9 3.8 7.9 2.9 2.1 4.6 11.9 12.0 18.1 19.3 12.9 11.9 11.8 12.1 11.5 11.3 12.4 11.8 5.6 16.0 23.6 11.1 10.3 4.2 23.1 15.1 3.4 22.1 11.4 9.1 16.7 15.7 15.7 20.2 10.4 60.7 8.8 14.7 58.7 22.0 26.4 9.8 8.4 14.4 1.2 33.1 9.2 32.0 24.3 12.4 23.4 10.0 1.3 27.6 8.9 49.5 25.9 10.1 8.5 16.9 20.3 22.0 7.8 18.2 15.5 14.6 5.4 10.3 27.2 18.7 10.3 8.5 7.2 22.3 13.9 9.1 12.2 17.8 15.6 52.0 16.6 11.0 6.6 11.3 13.3 10.9 14.0 6.4 5.3 42.0 11.4 36.4 16.4 15.7 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 885.9;Syncytiotrophoblasts: 648.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 818.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 78.1 180.7 99.3 39.6 108.9 71.8 85.5 114.4 140.4 105.3 119.6 80.1 55.0 76.9 47.7 198.0 65.2 60.3 81.7 96.6 107.4 94.2 292.3 93.3 49.7 117.4 107.9 107.4 74.0 61.5 48.7 116.9 117.3 87.2 20.7 17.2 133.7 70.5 98.6 119.7 64.1 38.3 109.2 63.6 99.8 51.7 102.7 26.9 59.1 49.9 26.0 86.9 124.1 124.3 131.3 131.7 15.0 128.3 141.2 122.5 6.0 143.9 178.8 120.3 133.6 112.1 148.6 51.7 62.7 208.9 48.6 172.9 23.6 152.0 26.2 115.1 163.4 92.5 65.1 267.1 265.1 155.0 35.3 159.2 180.7 104.3 101.3 116.6 113.2 82.0 383.2 109.4 100.6 818.5 63.4 267.9 32.4 361.1 42.9 88.2 127.9 72.8 129.0 404.5 60.4 53.8 47.7 405.7 125.7 7.6 84.0 436.6 137.5 212.7 82.2 71.0 109.6 37.5 18.0 41.2 236.0 211.3 152.5 62.2 312.2 59.6 77.9 218.1 64.0 56.8 52.6 62.6 251.5 57.8 45.5 51.7 12.0 73.5 151.5 291.4 72.6 178.6 99.3 108.9 114.4 140.4 96.6 107.4 117.4 107.9 117.3 109.2 102.7 124.3 99.1 125.0 88.1 22.9 33.1 102.1 231.9 248.1 188.4 73.4 174.9 218.4 41.9 104.4 162.7 152.6 10.4 885.9 80.1 53.0 320.8 201.0 4.6 59.1 72.2 86.7 84.5 70.0 16.8 193.0 113.5 103.1 46.4 46.9 71.7 95.7 77.1 262.0 311.4 25.2 17.2 97.7 191.2 177.0 107.7 13.3 134.2 137.0 240.1 20.6 137.0 158.7 41.2 25.1 45.7 170.2 108.8 179.8 45.5 132.4 179.9 73.8 135.8 43.2 138.1 143.3 113.1 8.4 5.7 236.4 123.5 648.5 41.8 222.0 122.3 206.6 ARVCF ENSG00000099889 "ARVCF delta catenin family member" O00192 22 19969896-20016823 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 22.9;Muller glia cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 20.1;REH: 10.5;SCLC-21H: 18.0;SH-SY5Y: 13.8;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016162, HPA055264, HPA063675" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cell Junctions" "CAB016162: AB_2058690, HPA055264: AB_2682766, HPA063675: AB_2685085" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (4.28e-2)" "unprognostic (3.35e-1)" "unprognostic (3.18e-2)" "unprognostic (4.79e-3)" "unprognostic (1.67e-2)" "unprognostic (2.06e-2)" "unprognostic (1.71e-2)" "unprognostic (2.09e-3)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (9.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.76e-6)" 3.8 3.1 6.4 0.7 5.4 3.2 4.4 18.4 6.2 4.3 1.2 5.9 1.0 4.8 3.2 1.3 3.5 1.3 6.4 5.6 7.1 6.2 6.8 4.5 0.5 7.0 5.2 3.5 5.1 1.7 9.4 1.0 5.7 5.7 0.3 1.4 7.0 1.7 7.4 4.7 2.8 0.7 4.9 10.8 4.8 4.9 8.3 0.2 15.6 1.2 0.1 2.8 2.8 5.1 4.1 0.4 5.5 7.1 0.1 0.0 5.6 1.0 0.4 0.3 0.6 1.1 0.9 1.7 4.5 0.5 0.5 3.8 0.9 1.8 0.0 0.5 6.8 0.5 0.5 4.4 1.6 0.6 1.3 0.1 0.7 0.3 0.2 0.3 4.5 1.3 20.1 0.6 0.1 3.8 0.3 2.6 5.6 1.3 2.3 10.5 0.3 0.5 0.9 0.9 18.0 13.8 1.1 1.7 2.7 0.9 1.5 0.5 1.7 0.1 15.6 0.7 0.3 2.2 0.7 0.5 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.4 18.4 6.2 5.6 7.1 7.0 5.2 5.7 4.9 8.3 5.1 2.3 3.2 2.6 24.2 0.7 2.0 3.0 4.4 0.6 9.7 6.6 7.9 6.0 5.7 3.2 1.8 22.9 5.6 2.3 1.8 0.0 8.9 2.7 2.4 0.9 3.0 9.0 4.0 4.7 5.5 2.2 2.4 1.5 4.5 0.0 4.7 2.5 4.1 1.4 5.0 6.2 7.0 10.2 1.0 1.2 1.7 4.1 0.8 3.6 5.6 0.0 21.7 7.2 8.0 1.8 10.7 0.6 3.4 0.9 4.7 0.8 5.6 4.9 8.6 0.0 7.7 6.2 2.3 8.4 0.4 1.8 4.4 0.6 1.6 2.1 1.5 TANGO2 "C22orf25, DKFZp761P1121" ENSG00000183597 "Transport and golgi organization 2 homolog" Q6ICL3 22 20017014-20067164 "Disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 78.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 111.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003080 Approved NA NA 200000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA003080: AB_1078350" "unprognostic (4.05e-1)" "unprognostic (1.90e-3)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (3.48e-1)" "unprognostic (1.37e-1)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (6.13e-2)" "unprognostic (6.76e-2)" "prognostic favorable (3.01e-4)" "unprognostic (2.21e-1)" "unprognostic (1.83e-3)" "unprognostic (3.95e-2)" "unprognostic (5.49e-2)" "unprognostic (2.60e-1)" "unprognostic (2.62e-2)" 17.0 26.7 20.9 13.8 19.2 50.5 13.4 19.1 23.8 10.9 15.9 14.9 9.8 13.0 9.2 11.5 10.9 10.9 78.9 21.8 22.4 21.3 20.0 19.2 17.7 24.7 26.6 7.9 15.4 27.7 19.7 11.6 30.2 17.1 11.3 6.4 12.2 12.2 27.7 12.8 16.2 12.0 20.6 34.0 21.2 7.5 25.7 12.4 24.3 29.0 11.7 15.1 9.7 20.5 15.6 14.2 4.8 9.6 33.6 10.9 8.7 15.7 20.8 14.5 12.8 10.0 12.1 6.2 11.1 42.4 20.2 18.9 11.2 17.5 9.2 36.8 11.4 16.9 11.9 12.0 24.6 15.7 29.1 15.6 12.9 21.0 11.6 14.5 21.6 10.4 44.0 13.1 20.8 17.7 10.3 10.7 2.3 37.7 9.5 9.5 12.9 4.0 11.7 19.9 8.4 4.7 16.1 27.7 35.3 10.3 7.0 14.3 14.7 19.0 14.4 25.2 11.0 6.7 4.1 6.4 25.9 12.9 13.6 76.3 44.1 77.8 14.9 53.4 16.2 20.5 15.9 19.2 41.6 15.7 10.0 13.1 55.8 31.3 70.1 14.3 28.7 39.6 20.9 19.2 19.1 23.8 21.8 22.4 24.7 26.6 30.2 20.6 25.7 20.5 5.8 16.0 5.8 10.7 11.9 3.8 3.9 4.2 2.2 4.9 3.9 3.4 17.1 10.0 4.6 7.3 4.2 10.6 10.2 11.5 19.6 11.5 5.5 2.7 3.4 5.7 6.6 111.4 20.6 9.7 17.4 5.9 9.2 4.9 15.2 4.5 6.4 6.4 39.4 10.1 13.3 7.0 8.2 21.6 7.1 15.9 5.0 24.0 19.6 15.9 24.8 7.6 19.6 3.0 30.9 11.6 9.2 4.9 7.2 4.8 13.8 7.7 6.1 2.9 19.7 3.0 6.6 4.8 3.1 5.3 4.5 11.5 9.7 13.0 6.3 3.5 DGCR8 "C22orf12, DGCRK6, Gy1, pasha" ENSG00000128191 "DGCR8 microprocessor complex subunit" Q8WYQ5 22 20080232-20111877 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 61.3;Rod photoreceptor cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076916, HPA079351" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Cytosol" "HPA076916: , HPA079351: " "unprognostic (2.57e-1)" "unprognostic (1.12e-1)" "unprognostic (1.97e-1)" "unprognostic (1.81e-1)" "unprognostic (8.34e-2)" "unprognostic (2.75e-3)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.34e-1)" "unprognostic (5.72e-3)" "unprognostic (2.83e-1)" "unprognostic (1.09e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.02e-2)" "unprognostic (4.20e-1)" "unprognostic (4.68e-2)" "unprognostic (2.26e-2)" 5.2 4.4 5.3 6.1 5.2 7.7 4.8 9.4 5.6 6.8 5.0 7.0 5.0 8.5 3.6 7.1 6.9 4.7 5.2 5.3 4.6 4.7 4.5 5.3 6.3 5.1 5.1 8.4 6.2 6.4 5.2 11.6 5.6 5.5 5.0 6.5 7.2 5.6 14.8 7.5 6.7 6.0 4.7 5.9 6.1 15.2 5.3 9.5 6.0 9.3 5.9 6.8 5.7 6.2 22.7 15.7 20.1 11.9 7.7 12.4 25.5 21.3 12.6 14.1 9.9 17.0 11.3 20.1 11.6 20.0 9.4 21.4 18.4 17.8 12.2 19.7 27.4 21.7 17.4 14.0 20.3 40.7 17.5 10.0 21.6 14.8 10.7 12.9 12.6 12.1 78.7 14.1 16.5 14.6 24.7 12.1 19.4 16.5 11.8 29.0 21.2 6.8 8.5 20.9 22.3 14.3 19.4 11.3 13.0 12.0 10.9 17.2 18.8 20.5 17.1 13.0 21.9 7.8 11.5 19.9 15.3 18.2 20.3 0.0 1.1 0.6 2.0 0.9 1.5 0.7 0.9 2.1 1.3 0.6 0.9 1.2 0.2 1.6 3.6 1.5 1.2 1.5 5.3 5.2 9.4 5.6 5.3 4.6 5.1 5.1 5.6 4.7 5.3 6.2 8.1 6.4 7.9 11.8 6.0 9.6 5.2 6.8 10.2 37.1 9.1 8.0 4.2 11.5 7.3 5.5 39.6 13.6 6.9 9.6 0.0 6.1 61.3 5.5 8.3 10.2 7.3 10.3 12.4 10.2 11.2 7.3 12.8 7.3 3.8 19.2 9.7 14.4 5.3 43.7 12.7 10.3 4.1 8.4 6.5 39.2 18.3 5.0 5.4 6.5 7.2 10.9 11.3 9.5 14.0 10.9 5.8 10.5 9.3 8.6 6.2 3.4 8.1 60.7 6.6 9.7 8.1 25.2 17.5 10.4 9.2 13.5 9.3 15.1 9.7 5.6 TRMT2A HTF9C ENSG00000099899 "TRNA methyltransferase 2 homolog A" Q8IZ69 22 20111875-20117392 "Plasma proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 131.7;Late spermatids: 206.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 84.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001077 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA001077: AB_1079092" "unprognostic (5.01e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (9.70e-2)" "unprognostic (1.17e-1)" "unprognostic (8.05e-3)" "unprognostic (2.19e-3)" "unprognostic (5.93e-3)" "unprognostic (4.04e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (2.99e-8)" "unprognostic (4.54e-2)" "unprognostic (1.58e-1)" "unprognostic (3.80e-1)" "unprognostic (1.14e-3)" 15.7 24.0 11.2 7.6 11.4 8.2 16.8 11.4 16.8 17.7 12.0 15.3 8.7 14.7 4.4 16.3 16.0 6.4 13.8 11.3 10.6 18.0 31.4 12.9 13.1 12.2 10.9 15.5 24.2 5.8 21.8 5.5 11.9 20.7 2.7 2.4 19.1 5.6 15.6 17.1 16.3 3.6 11.1 28.1 17.2 22.8 11.7 10.2 18.7 4.8 5.2 15.3 13.8 12.9 13.8 15.4 6.1 9.9 6.0 4.4 20.9 12.3 6.4 9.7 8.8 18.5 11.7 18.7 10.2 5.9 7.4 21.0 4.5 7.2 1.4 20.3 52.2 22.7 23.3 17.0 15.8 34.9 21.2 8.2 9.0 10.3 3.8 6.7 9.9 15.4 84.5 13.1 6.8 21.7 19.5 21.6 11.2 16.2 19.9 22.8 10.6 7.4 5.7 15.1 16.0 12.2 7.9 18.9 21.5 2.6 13.6 28.7 9.3 11.5 15.4 9.3 10.6 44.3 21.6 14.6 15.2 14.7 11.9 10.2 12.2 7.4 9.8 15.3 14.4 9.7 10.3 11.7 14.3 6.3 11.1 11.1 1.5 10.6 13.5 12.7 8.4 12.3 11.2 11.4 11.4 16.8 11.3 10.6 12.2 10.9 11.9 11.1 11.7 12.9 10.8 12.8 13.8 13.4 13.4 9.8 10.2 13.9 9.6 12.5 15.9 18.0 7.4 14.3 14.1 11.0 8.4 25.0 18.3 17.0 13.7 12.3 131.7 8.9 9.5 10.9 18.6 14.5 6.9 13.0 18.9 10.8 15.8 6.6 25.4 15.8 8.9 18.6 25.0 15.2 7.4 13.4 14.2 18.9 8.9 206.4 17.7 13.7 7.2 4.7 16.9 22.7 12.3 3.5 9.0 13.0 13.4 14.3 18.1 12.1 14.4 10.5 11.9 12.8 6.6 11.8 11.2 16.4 13.7 10.4 11.2 28.5 16.6 19.2 20.0 9.7 RANBP1 HTF9A ENSG00000099901 "RAN binding protein 1" P43487 22 20115938-20127355 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 754.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 2431.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065868, HPA065931" Supported Enhanced Cytosol NA NA 1400000 "Cluster 26: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA065868: AB_2685572, HPA065931: AB_2685580" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (4.43e-3)" "unprognostic (6.55e-3)" "unprognostic (4.35e-2)" "unprognostic (2.50e-2)" "prognostic unfavorable (1.58e-6)" "unprognostic (2.83e-2)" "unprognostic (2.21e-2)" "unprognostic (5.67e-3)" "unprognostic (1.54e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.40e-2)" "unprognostic (3.95e-1)" "unprognostic (4.44e-2)" "unprognostic (7.30e-2)" 65.5 68.0 37.6 63.3 38.6 117.5 60.7 40.2 47.9 67.1 28.8 63.9 52.9 66.7 21.4 94.7 61.2 30.0 47.5 39.7 40.5 64.8 86.7 53.5 94.7 41.1 39.1 61.0 54.0 35.9 50.3 46.2 41.4 49.8 42.9 35.3 51.8 34.3 54.9 61.8 60.6 36.2 40.8 71.1 55.5 117.8 39.6 104.0 46.5 34.8 72.6 61.9 64.7 43.7 434.6 218.5 479.7 263.2 79.1 93.8 403.7 388.7 169.3 494.6 356.4 401.5 150.8 669.8 169.7 157.8 224.9 394.2 449.4 340.4 269.6 290.1 1071.3 562.6 218.5 426.6 120.3 913.7 294.4 103.9 158.7 393.0 139.2 114.3 227.1 300.2 2431.9 261.1 226.8 339.2 665.5 622.0 547.2 553.8 380.8 667.4 674.7 172.6 171.6 233.9 478.6 354.7 356.6 196.4 236.6 210.3 137.1 378.9 176.4 341.5 668.1 258.7 438.3 260.9 383.6 1066.0 186.9 405.9 292.7 21.1 94.7 75.8 71.3 101.6 78.8 123.1 101.6 91.1 111.5 119.1 101.8 77.0 9.5 90.8 93.6 103.6 115.4 102.5 37.6 38.6 40.2 47.9 39.7 40.5 41.1 39.1 41.4 40.8 39.6 43.7 133.1 35.3 37.1 14.7 135.0 274.4 195.0 260.6 109.3 44.4 142.3 175.6 47.1 104.4 104.8 90.1 6.2 409.2 103.8 106.4 277.8 188.5 394.2 104.6 131.1 143.5 117.6 259.2 22.2 112.3 754.9 156.7 72.4 86.7 64.7 187.2 93.5 169.5 268.7 37.0 21.4 194.0 209.5 85.5 223.3 236.1 145.1 95.3 177.9 6.5 140.6 103.5 87.6 7.5 23.9 150.0 109.3 136.9 179.6 338.0 107.3 213.7 93.8 39.0 98.6 110.9 289.5 505.1 435.2 220.1 294.9 194.7 119.2 176.5 273.6 218.2 ZDHHC8 "KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol Nucleoplasm "HPA003422: AB_1080640" "unprognostic (1.00e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (3.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.49e-1)" "unprognostic (8.02e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-3)" "unprognostic (9.34e-3)" "unprognostic (3.20e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (1.11e-1)" "unprognostic (1.02e-1)" "unprognostic (9.88e-2)" "unprognostic (9.57e-2)" 31.6 31.2 13.8 18.6 15.1 10.7 30.4 11.3 26.4 32.6 0.0 22.8 12.1 31.2 7.5 29.3 27.7 13.0 31.6 13.9 7.0 30.4 36.1 31.0 17.1 12.2 10.0 34.6 35.6 14.4 41.3 16.9 9.9 28.1 7.0 7.4 27.6 15.4 23.6 32.2 24.7 13.1 6.6 35.7 26.4 14.9 12.3 13.7 37.3 10.3 11.7 25.3 30.9 12.8 30.0 18.7 29.3 38.7 42.0 25.0 26.3 55.1 37.3 36.6 32.6 9.8 15.2 0.1 22.3 46.0 19.8 40.2 15.5 42.2 18.0 43.2 59.4 14.5 57.2 23.0 34.5 0.0 19.5 43.7 27.9 28.2 23.6 22.5 41.4 21.0 101.4 22.8 33.0 14.7 17.8 39.1 14.9 13.2 29.4 37.8 25.6 10.9 15.6 35.9 46.9 23.7 22.4 10.7 26.6 13.1 0.7 20.4 48.0 82.5 59.8 46.8 25.0 32.6 11.5 11.7 24.2 18.7 24.8 1.3 0.4 0.1 0.8 0.5 0.4 0.2 0.2 0.4 0.1 0.5 0.4 0.5 0.0 0.4 0.2 1.3 0.7 0.2 13.8 15.1 11.3 26.4 13.9 7.0 12.2 10.0 9.9 6.6 12.3 12.8 17.4 3.2 3.1 17.6 3.7 9.1 3.8 3.6 5.7 11.9 8.2 8.1 7.1 4.3 3.5 11.0 14.6 3.6 9.2 4.3 1.9 5.2 0.5 4.3 15.7 11.5 4.2 0.8 16.6 4.5 8.5 9.3 10.2 8.7 5.7 8.7 10.4 9.8 4.9 13.5 9.9 5.9 10.2 5.0 5.0 2.1 10.8 5.7 5.4 9.4 3.7 7.4 1.0 13.0 13.3 7.7 5.4 14.7 2.7 7.6 2.7 2.1 1.5 10.8 6.6 10.5 6.8 1.4 3.8 5.5 9.8 3.4 4.2 8.0 5.0 3.4 CCDC188 ENSG00000234409 "Coiled-coil domain containing 188" H7C350 22 20148416-20151055 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 40.2" "Group enriched" "Detected in some" 89 "Early spermatids: 313.0;Late spermatids: 988.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Cell line enhanced" "Detected in some" "AF22: 4.0;SCLC-21H: 5.5;SH-SY5Y: 7.2;TIME: 3.1;U-2 OS: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA049901 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear bodies" Nucleoplasm "HPA049901: AB_2680943" "unprognostic (9.83e-2)" "unprognostic (3.09e-2)" "unprognostic (9.79e-2)" "unprognostic (6.42e-3)" "unprognostic (2.45e-1)" "unprognostic (3.83e-2)" "unprognostic (1.04e-2)" "unprognostic (1.02e-1)" "unprognostic (8.43e-2)" "unprognostic (4.08e-3)" "unprognostic (1.67e-5)" "unprognostic (1.16e-1)" "unprognostic (5.37e-5)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-2)" 1.5 0.6 0.4 0.5 0.6 0.5 1.3 0.5 0.6 0.8 0.0 0.5 0.8 0.8 0.0 0.3 1.0 0.3 0.6 1.0 1.3 0.9 0.2 1.0 0.6 0.1 0.0 0.3 0.5 0.0 9.6 0.6 0.0 0.5 0.0 0.2 0.4 0.0 0.6 1.1 0.6 0.2 0.0 1.5 0.5 40.2 1.4 0.0 0.6 0.0 0.0 0.7 0.6 0.0 0.0 0.0 4.0 0.2 0.0 0.5 0.0 1.1 0.5 0.9 0.7 0.0 0.1 0.0 0.1 0.6 0.1 0.2 0.0 0.0 0.0 0.1 0.0 1.1 0.2 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.2 2.6 0.8 0.3 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 5.5 7.2 0.4 0.0 0.4 0.1 0.0 0.1 3.1 1.6 3.0 2.0 0.2 0.5 0.1 0.2 2.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.6 0.5 0.6 1.0 1.3 0.1 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.0 7.3 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 988.5 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.1 4.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 DGCR6L FLJ10666 ENSG00000128185 "DiGeorge syndrome critical region gene 6 like" Q9BY27 22 20314238-20320080 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Late spermatids: 2787.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (1.91e-1)" "prognostic favorable (3.82e-5)" "unprognostic (2.74e-2)" "unprognostic (4.61e-3)" "unprognostic (3.97e-2)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "prognostic favorable (5.37e-4)" "unprognostic (1.44e-1)" "unprognostic (4.39e-2)" "unprognostic (3.29e-3)" "unprognostic (9.07e-3)" "unprognostic (6.72e-3)" "unprognostic (4.37e-2)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (2.97e-1)" 34.2 44.8 75.9 15.3 73.2 30.9 36.3 68.7 95.7 38.0 72.4 46.5 19.8 33.6 23.8 41.2 31.7 18.7 67.8 72.9 71.4 57.6 152.6 28.6 24.7 71.2 71.7 36.3 43.1 42.1 43.3 12.5 71.9 51.0 11.4 8.6 45.2 29.0 81.1 54.1 29.8 15.3 71.2 33.8 40.9 132.0 74.1 27.6 45.9 44.1 14.6 39.9 35.3 69.5 34.0 38.0 25.5 64.5 36.6 36.6 26.7 32.4 37.7 58.7 42.6 19.7 16.4 9.1 41.4 35.9 23.7 33.8 19.3 39.0 9.6 43.7 97.6 21.7 26.6 36.8 43.3 46.6 21.0 41.0 35.4 23.0 24.7 22.7 41.4 42.3 99.9 39.4 38.3 79.2 35.1 42.4 18.7 67.2 56.1 61.0 58.5 17.7 31.1 26.3 50.4 36.9 53.3 34.7 60.6 10.3 50.3 37.0 32.5 69.4 80.3 37.1 32.1 34.9 39.5 20.9 56.1 58.5 47.5 115.6 102.0 145.5 104.6 93.3 104.0 81.7 130.7 117.7 93.9 73.5 119.9 113.9 34.0 139.1 92.7 88.2 129.8 120.4 75.9 73.2 68.7 95.7 72.9 71.4 71.2 71.7 71.9 71.2 74.1 69.5 43.6 28.9 30.2 4.9 29.7 43.7 34.2 53.4 33.0 18.6 79.4 106.3 80.3 57.2 41.1 35.0 4.2 67.7 43.1 65.2 133.1 72.2 529.8 28.0 23.2 40.2 52.8 37.2 6.3 63.0 86.4 43.3 26.0 17.5 39.3 38.5 62.4 166.9 80.2 28.6 7.3 64.4 34.6 78.3 52.9 2787.0 70.2 41.7 56.9 1.9 55.5 58.2 95.8 6.0 7.9 51.7 58.5 70.7 44.2 26.2 166.0 164.5 42.5 24.9 46.0 23.6 47.2 117.3 91.0 62.3 60.9 21.9 56.7 36.2 69.0 33.9 USP41 ENSG00000161133 "Ubiquitin specific peptidase 41" 22 20350578-20377251 "Metabolic proteins, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 1.2;SCLC-21H: 1.5" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "unprognostic (4.01e-6)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (4.63e-3)" "unprognostic (7.44e-2)" "unprognostic (1.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.34e-2)" "unprognostic (3.66e-2)" "unprognostic (9.91e-5)" "unprognostic (3.43e-2)" "unprognostic (3.51e-2)" "unprognostic (2.54e-2)" "unprognostic (4.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.63e-1)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.1 0.0 1.2 0.0 0.0 0.5 1.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF74 "Cos52, Zfp520, ZNF520" ENSG00000185252 "Zinc finger protein 74" Q16587 22 20394115-20408461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "K-562: 47.9" HPA003354 Approved Supported "Nucleoplasm,Actin filaments" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Actin filaments" "HPA003354: AB_1080747" "unprognostic (1.40e-1)" "unprognostic (2.36e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (1.02e-1)" "unprognostic (8.13e-3)" "unprognostic (1.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (1.20e-3)" "unprognostic (3.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.58e-2)" "unprognostic (3.04e-1)" "unprognostic (7.91e-2)" "unprognostic (1.44e-3)" 1.7 2.4 5.0 1.2 5.1 0.6 2.1 4.4 5.2 4.5 3.9 4.3 1.3 4.7 1.9 3.2 3.1 0.8 2.3 5.1 5.2 2.8 2.4 1.9 1.5 4.8 4.8 4.4 4.2 2.7 5.4 1.5 4.8 3.6 1.4 1.7 2.9 3.0 4.7 2.9 2.2 2.4 4.4 2.6 3.1 1.3 5.2 2.5 2.5 2.4 1.1 3.9 3.0 5.2 4.3 4.1 10.4 15.8 2.9 2.8 8.2 4.0 2.9 4.8 4.5 5.7 2.0 0.1 5.6 3.2 1.6 5.2 7.8 5.1 2.7 2.8 17.8 4.9 2.0 8.1 4.8 10.7 5.1 3.1 8.6 3.7 4.2 3.6 4.8 9.3 47.9 0.1 3.4 7.1 10.2 6.6 11.6 8.9 7.2 14.0 6.1 1.6 3.1 4.6 22.8 14.1 4.4 7.9 9.3 5.2 3.6 5.1 3.4 4.6 9.5 5.8 3.0 5.2 6.2 0.1 1.1 6.1 4.0 0.0 1.2 0.9 2.0 1.0 1.6 1.1 1.5 2.4 1.9 1.0 1.8 1.7 0.0 3.8 0.7 1.3 1.4 1.9 5.0 5.1 4.4 5.2 5.1 5.2 4.8 4.8 4.8 4.4 5.2 5.2 1.4 3.2 2.0 3.6 2.1 1.5 1.9 1.6 2.8 5.1 3.6 3.0 3.1 2.8 2.5 0.0 2.1 3.1 3.8 0.9 3.9 3.8 0.5 2.3 3.7 1.7 4.2 2.1 8.5 2.4 4.6 3.5 3.1 2.0 0.0 5.6 2.5 1.7 2.2 3.3 8.8 2.3 2.0 0.6 0.3 0.3 7.2 1.0 0.0 2.8 1.6 2.6 3.1 6.0 6.6 2.5 1.0 4.9 0.9 4.0 1.5 1.7 0.6 2.1 6.6 2.7 3.2 4.3 3.0 1.8 1.0 1.1 2.7 4.4 2.8 1.1 SCARF2 "HUMZD58C02, SREC-II, SREC2" ENSG00000244486 "Scavenger receptor class F member 2" Q96GP6 22 20424584-20437826 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 44.8;Fibroblasts: 21.2;Leydig cells: 13.4;Peritubular cells: 17.7;Sertoli cells: 13.1;Smooth muscle cells: 19.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 25.5;SH-SY5Y: 28.5;SK-MEL-30: 31.7;U-138 MG: 38.7;U-2 OS: 40.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA035079 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Nuclear bodies, Cytosol" "HPA035079: AB_10670287" "unprognostic (2.12e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (2.29e-1)" "unprognostic (2.92e-1)" "unprognostic (7.68e-2)" "unprognostic (7.87e-2)" "unprognostic (8.27e-2)" "unprognostic (2.18e-2)" "unprognostic (1.68e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.38e-3)" "unprognostic (3.18e-2)" "unprognostic (3.00e-3)" "prognostic unfavorable (4.28e-4)" 15.1 5.4 2.4 1.9 2.6 0.4 10.7 0.5 3.3 19.1 4.1 10.0 1.3 22.4 0.5 3.6 15.5 3.6 10.3 2.1 3.9 10.6 3.6 23.2 1.3 5.1 3.2 20.2 4.0 0.4 5.4 3.7 2.2 15.5 0.3 0.1 4.6 4.5 3.1 10.1 6.0 2.2 2.0 9.4 7.8 2.7 4.7 0.2 11.8 0.4 0.2 13.3 13.2 1.3 0.7 0.4 5.8 10.1 3.4 4.8 2.3 25.5 10.8 6.2 3.3 0.1 0.1 0.4 14.6 12.7 0.4 0.2 3.4 0.1 0.7 0.9 21.6 2.1 0.5 4.9 21.3 0.0 1.1 8.2 0.1 3.0 1.5 3.0 3.0 0.1 0.2 0.2 2.2 1.1 0.0 0.5 7.8 0.0 3.3 0.6 16.1 0.0 0.1 0.1 2.5 28.5 0.1 0.0 31.7 1.1 0.9 0.1 3.7 38.7 40.7 1.0 5.9 1.2 0.5 0.4 0.1 0.5 19.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.4 2.6 0.5 3.3 2.1 3.9 5.1 3.2 2.2 2.0 4.7 1.3 3.6 0.0 0.0 1.6 0.1 2.8 1.6 0.7 0.0 2.9 0.3 0.9 44.8 0.0 0.3 0.0 2.1 0.4 0.3 0.1 0.0 0.0 0.3 2.6 8.9 10.5 0.0 0.0 1.9 0.0 1.6 21.2 1.5 1.0 0.0 0.6 3.9 0.7 0.7 0.0 5.2 0.2 0.0 0.8 2.4 0.5 13.4 0.4 3.6 6.5 0.0 0.3 1.0 3.0 1.1 0.0 0.1 17.7 0.2 7.1 0.0 0.2 4.2 0.8 13.1 1.4 19.5 1.1 0.7 0.3 2.7 0.4 1.2 2.1 0.2 0.6 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 MED15 "Arc105, CAG7A, PCQAP, TIG-1, TNRC7" ENSG00000099917 "Mediator complex subunit 15" Q96RN5 22 20495913-20587632 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 240.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003179 Approved Supported Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "HPA003179: AB_1079581" "unprognostic (7.98e-2)" "unprognostic (2.26e-1)" "unprognostic (1.70e-1)" "prognostic favorable (7.30e-5)" "unprognostic (2.53e-1)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.73e-2)" "unprognostic (1.12e-3)" "unprognostic (3.46e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.32e-2)" "unprognostic (2.50e-1)" "unprognostic (3.60e-2)" "unprognostic (5.57e-2)" 33.0 32.6 16.4 28.5 20.5 42.1 28.7 24.8 33.5 31.0 12.9 34.1 31.7 40.5 6.2 33.4 26.2 23.1 26.4 17.9 18.4 24.1 14.9 35.8 31.6 14.9 15.7 26.5 22.4 15.2 20.6 25.0 18.5 26.2 11.9 8.8 26.7 14.9 55.1 36.1 30.9 17.3 9.1 31.8 23.9 20.1 13.5 23.2 23.3 15.8 16.1 33.9 30.7 26.2 73.6 38.5 24.2 29.3 25.0 24.2 44.3 72.9 52.9 56.4 51.9 58.8 32.5 29.6 32.9 51.8 25.4 74.1 22.1 54.2 22.7 42.5 39.5 56.4 42.2 43.2 41.4 51.7 49.6 29.7 41.7 44.7 45.0 31.8 44.3 22.2 240.2 26.8 36.4 49.0 21.7 29.4 26.2 32.2 26.0 37.7 54.7 12.1 34.3 52.7 22.7 39.0 55.0 54.9 77.4 15.7 31.0 28.7 80.4 90.3 67.6 48.7 59.4 35.3 34.3 22.6 65.3 31.5 82.5 6.3 11.8 10.5 24.3 12.4 11.5 5.7 16.9 27.8 10.1 6.3 9.7 16.4 13.0 21.9 23.1 9.0 28.9 15.0 16.4 20.5 24.8 33.5 17.9 18.4 14.9 15.7 18.5 9.1 13.5 26.2 24.4 51.3 30.9 26.4 19.4 29.8 26.3 25.1 22.8 20.2 18.7 17.5 4.6 12.8 26.5 25.8 18.8 48.9 33.4 46.9 15.6 32.3 34.3 36.3 24.9 25.6 18.0 10.3 31.4 28.6 42.0 21.4 39.8 49.1 20.8 21.3 23.6 9.7 31.4 15.2 32.7 26.0 14.2 24.1 35.1 19.8 14.3 31.1 24.9 34.7 30.7 13.8 47.4 21.6 28.2 67.8 43.4 14.7 24.8 40.2 36.5 11.9 33.1 16.3 46.0 23.2 23.3 22.6 15.4 26.2 27.6 61.8 43.7 24.7 25.4 36.5 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 209.1;Inhibitory neurons: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 18.8 21.6 45.2 19.2 61.0 24.1 16.8 2.1 74.4 20.4 9.6 23.7 15.8 24.2 9.9 14.3 19.5 13.5 21.5 65.3 9.0 21.3 25.2 19.1 20.5 14.6 4.8 21.4 18.7 34.5 25.2 17.9 14.5 19.5 14.9 27.7 16.5 16.9 23.6 15.1 22.9 21.9 0.0 21.0 26.0 25.7 8.6 34.3 18.0 15.9 18.0 22.2 16.9 43.3 24.5 20.2 17.4 26.3 48.7 29.1 24.9 21.6 32.6 31.3 30.4 15.9 10.2 45.6 12.6 43.9 30.7 21.1 33.4 20.9 19.0 38.9 50.9 47.1 27.1 18.3 24.3 47.0 36.1 26.2 12.9 26.7 14.7 20.4 25.8 13.8 130.2 37.6 24.6 33.8 41.6 16.0 13.8 43.4 20.6 41.1 38.1 8.5 17.3 38.3 42.6 31.0 28.4 32.6 22.6 24.3 27.6 21.3 26.2 56.4 29.1 21.1 18.5 28.6 31.3 35.8 37.4 33.2 24.1 2.1 3.7 5.3 3.2 3.8 3.1 3.4 3.6 3.9 2.5 3.4 3.6 5.0 5.1 7.0 3.3 8.5 4.3 2.2 45.2 61.0 2.1 74.4 65.3 9.0 14.6 4.8 14.5 0.0 8.6 43.3 13.0 12.8 30.4 65.6 14.7 10.1 6.5 7.6 9.6 35.8 17.2 14.4 30.2 20.0 10.5 7.3 47.9 17.8 21.5 19.7 1.9 9.7 36.5 10.3 17.9 15.5 19.2 12.4 209.1 6.3 19.6 15.6 38.7 15.8 12.0 13.8 11.4 19.7 20.1 37.0 127.4 16.7 10.2 21.0 12.6 25.3 19.9 20.2 10.6 39.4 10.9 23.1 16.5 50.3 88.4 8.9 9.7 24.0 15.5 10.1 23.8 10.3 9.6 25.4 26.3 14.5 19.3 35.3 29.6 14.1 9.8 20.0 15.3 26.1 14.3 8.9 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SNAP29 "CEDNIK, SNAP-29" ENSG00000099940 "Synaptosome associated protein 29" O95721 22 20859007-20891214 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" "Ichthyosis, Neuropathy, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 524.1;Late spermatids: 191.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 220.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031823, CAB037092, HPA056492" Supported Supported Nucleoplasm,Cytosol NA NA 110000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Nucleoplasm "CAB037092: AB_477491, HPA031823: AB_10602407, HPA056492: AB_2683151" "unprognostic (1.76e-1)" "prognostic favorable (6.99e-4)" "unprognostic (3.72e-3)" "unprognostic (3.26e-2)" "unprognostic (7.83e-3)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (2.05e-2)" "unprognostic (1.34e-2)" "unprognostic (2.60e-2)" "unprognostic (3.68e-2)" "unprognostic (6.85e-2)" "unprognostic (1.22e-1)" "unprognostic (2.52e-1)" "unprognostic (1.45e-1)" "unprognostic (4.51e-3)" "unprognostic (6.08e-2)" 18.3 18.0 10.8 17.1 11.5 18.9 15.9 12.8 18.0 15.3 11.7 19.9 17.4 14.5 11.1 23.1 12.8 13.7 18.9 12.0 11.4 16.8 35.8 13.9 17.0 12.6 11.7 13.6 17.3 18.7 11.0 19.1 12.4 13.5 17.8 14.4 15.8 14.1 31.2 19.0 16.6 18.1 11.2 16.8 18.6 56.5 11.0 24.1 12.3 27.4 19.7 15.6 15.7 12.5 48.4 19.4 27.1 22.3 30.0 43.5 35.0 44.8 40.3 49.5 49.5 26.8 16.7 30.1 27.9 42.2 50.0 27.8 35.8 30.4 53.2 43.5 27.3 50.0 20.9 29.2 42.7 44.6 38.8 34.6 42.2 51.9 37.2 34.0 35.1 25.5 220.8 41.5 46.2 33.1 40.7 42.9 8.9 55.9 20.2 38.9 60.6 12.1 29.1 25.5 22.0 26.2 48.0 29.9 51.0 33.3 46.8 35.3 30.7 50.1 45.5 34.6 35.6 42.4 74.0 55.3 37.5 29.8 36.7 49.0 43.7 52.4 21.7 61.5 22.7 23.7 21.2 23.7 38.0 22.6 19.3 19.8 49.0 60.0 77.9 43.6 34.5 34.6 10.8 11.5 12.8 18.0 12.0 11.4 12.6 11.7 12.4 11.2 11.0 12.5 24.4 12.8 29.0 8.8 19.0 16.7 24.5 34.7 17.6 12.4 26.4 22.5 22.5 21.5 22.9 23.9 12.5 80.1 35.9 40.0 43.0 40.3 524.1 26.3 28.2 30.1 22.1 36.4 9.6 50.0 146.0 28.4 26.5 22.3 29.2 25.0 29.6 46.5 74.4 20.2 7.2 27.6 32.6 49.4 23.1 191.7 33.2 46.7 35.6 2.8 51.4 30.6 48.4 10.6 12.1 59.4 21.4 36.5 44.1 26.7 38.8 36.8 37.4 13.2 39.5 21.9 27.9 113.5 81.1 28.2 15.5 98.2 26.5 70.3 25.3 29.7 CRKL ENSG00000099942 "CRK like proto-oncogene, adaptor protein" P46109 22 20917407-20953747 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 344.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000532, HPA001100" Uncertain Enhanced Nucleoplasm,Cytosol NA NA 2100000 "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Cytosol "HPA000532: AB_2666019, HPA001100: AB_1078569" "unprognostic (5.54e-2)" "unprognostic (2.66e-1)" "unprognostic (5.87e-2)" "unprognostic (2.40e-2)" "unprognostic (3.06e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-2)" "unprognostic (6.51e-2)" "unprognostic (2.35e-2)" "unprognostic (4.60e-1)" "unprognostic (2.71e-1)" "unprognostic (5.99e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (8.40e-2)" "unprognostic (1.43e-1)" "unprognostic (9.52e-2)" "unprognostic (1.61e-2)" 16.7 14.8 34.5 18.4 34.9 53.7 16.3 34.6 35.7 17.5 26.0 18.4 22.0 19.4 13.0 26.6 20.4 14.3 25.1 33.7 33.5 17.1 27.3 20.7 25.5 36.8 37.0 27.4 23.5 19.1 16.1 25.9 34.0 16.5 19.6 22.4 14.8 19.0 54.3 24.9 19.7 19.5 38.8 22.4 14.7 13.3 38.9 33.3 14.8 43.0 27.6 18.9 18.4 36.0 43.9 25.8 56.7 44.8 37.5 23.9 61.0 29.0 35.5 43.7 49.1 42.8 19.2 56.1 22.9 30.8 30.0 54.8 67.2 46.3 51.7 47.7 65.5 77.7 28.6 47.3 37.4 83.5 38.0 24.3 60.3 38.1 64.6 35.7 39.1 44.3 344.9 44.8 35.7 41.2 49.0 39.0 44.8 45.5 27.7 62.7 89.9 13.5 29.2 37.8 36.5 46.9 48.6 42.4 36.4 67.7 36.4 45.9 31.9 69.0 77.8 26.2 37.2 42.7 44.4 64.1 51.1 34.8 43.3 16.2 15.0 22.1 18.5 13.9 19.3 12.1 16.2 18.4 16.5 11.4 19.7 18.9 15.9 12.9 26.1 8.3 14.4 21.2 34.5 34.9 34.6 35.7 33.7 33.5 36.8 37.0 34.0 38.8 38.9 36.0 11.8 9.6 17.8 17.3 18.6 54.2 13.5 15.2 29.6 17.8 19.7 14.2 23.1 7.2 12.2 5.5 14.6 19.6 26.4 19.6 1.9 7.7 30.4 19.3 15.3 15.0 20.4 28.6 23.9 8.6 42.4 16.5 10.2 18.4 1.3 15.8 20.7 25.0 17.5 18.5 18.6 19.9 8.2 19.5 20.8 52.5 15.2 15.2 24.9 9.4 19.0 17.5 21.6 16.6 25.0 11.2 11.8 15.4 14.1 19.0 18.5 10.7 14.8 13.2 13.1 15.7 12.1 12.7 11.0 40.2 60.4 27.2 17.8 12.7 18.5 18.6 AIFM3 "AIFL, FLJ30473" ENSG00000183773 "Apoptosis inducing factor mitochondria associated 3" Q96NN9 22 20965108-20981360 "Predicted intracellular proteins" "Apoptosis, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 70.4;choroid plexus: 136.0" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Distal enterocytes: 76.5;Intestinal goblet cells: 31.3;Muller glia cells: 25.3;Paneth cells: 27.5;Undifferentiated cells: 37.9" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "classical monocyte: 1.1;intermediate monocyte: 3.0;myeloid DC: 1.9;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 24 "dendritic cells: 1.9;monocytes: 3.0" "Cell line enhanced" "Detected in some" "Hep G2: 7.6;HMC-1: 10.8;T-47d: 5.3;THP-1: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001271 Supported Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA001271: AB_1078114" "unprognostic (1.39e-1)" "unprognostic (1.97e-1)" "unprognostic (7.49e-2)" "unprognostic (9.99e-2)" "unprognostic (6.79e-2)" "unprognostic (2.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.73e-3)" "unprognostic (3.28e-1)" "unprognostic (1.56e-1)" "unprognostic (4.13e-3)" "unprognostic (5.13e-2)" "unprognostic (7.99e-2)" "unprognostic (6.78e-2)" "unprognostic (1.47e-1)" "unprognostic (3.37e-1)" "prognostic favorable (7.13e-5)" 0.5 0.4 41.5 3.1 36.8 3.7 0.4 39.6 52.9 0.3 136.0 24.8 2.5 0.4 0.0 0.4 0.5 0.6 0.3 29.9 31.4 0.8 0.3 1.1 0.6 46.2 43.7 0.3 0.4 0.5 4.4 0.4 43.2 1.0 8.4 1.8 1.0 0.7 0.1 0.1 1.9 0.8 38.0 2.1 0.5 0.6 70.4 0.1 0.3 0.0 0.0 1.2 0.3 24.9 1.0 1.7 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.2 0.1 0.0 0.0 0.2 0.0 1.9 0.0 7.6 0.2 0.0 10.8 0.5 0.6 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.3 0.0 1.3 1.4 0.9 0.8 0.1 0.0 0.1 5.3 7.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 3.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.5 41.5 36.8 39.6 52.9 29.9 31.4 46.2 43.7 43.2 38.0 70.4 24.9 1.0 0.0 1.5 92.1 1.0 0.6 1.9 1.7 0.6 14.5 3.1 2.4 2.9 0.0 1.4 1.8 6.2 1.0 0.0 76.5 11.7 0.7 0.0 1.7 0.4 0.5 10.3 0.0 12.5 0.6 0.7 0.6 1.5 1.4 1.3 0.5 1.4 2.4 3.6 0.0 8.1 31.3 2.0 3.2 1.9 0.1 0.0 2.5 0.0 4.7 3.2 25.3 0.0 2.5 1.6 0.5 27.5 0.0 0.3 2.2 4.8 8.1 1.9 3.7 0.0 0.2 1.2 0.4 1.9 0.7 0.9 0.8 0.2 0.3 37.9 2.8 LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: AB_2686031, HPA071248: AB_2686372" "unprognostic (1.88e-2)" "unprognostic (1.01e-1)" "unprognostic (1.90e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (2.44e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (9.81e-2)" "unprognostic (3.55e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-3)" "unprognostic (4.29e-2)" "unprognostic (1.65e-1)" "unprognostic (6.25e-2)" "unprognostic (1.25e-2)" 18.4 15.2 9.0 8.9 9.7 6.0 17.3 8.9 10.1 20.1 7.2 20.1 9.9 23.3 4.4 12.6 18.5 9.4 13.4 9.1 9.1 15.8 12.0 16.0 7.3 10.3 9.5 19.5 12.4 11.5 24.7 9.8 10.8 16.2 6.4 3.4 13.0 8.6 14.7 13.6 15.9 11.3 8.1 18.3 13.9 8.2 8.9 6.5 18.8 8.0 5.7 18.1 15.8 9.3 10.3 8.4 12.2 15.0 27.6 18.9 9.6 20.8 14.6 11.6 15.8 4.9 4.2 11.0 7.6 23.4 10.7 13.7 9.3 17.1 4.7 20.5 21.0 11.8 11.8 7.4 14.6 6.4 14.9 17.5 8.5 14.7 10.6 18.4 22.9 10.0 49.8 18.5 13.4 6.3 11.5 6.0 3.8 12.6 9.1 13.4 17.8 4.4 9.2 13.9 11.9 17.9 11.3 19.5 12.4 7.4 9.1 11.7 20.6 27.0 13.3 12.3 11.5 8.0 7.4 3.2 12.2 6.2 13.5 0.0 0.5 0.0 0.7 0.7 0.4 0.4 0.3 0.8 0.4 0.1 0.4 0.3 0.0 0.3 1.0 0.3 0.1 0.5 9.0 9.7 8.9 10.1 9.1 9.1 10.3 9.5 10.8 8.1 8.9 9.3 12.4 12.8 8.6 20.5 7.9 2.2 1.8 3.7 4.0 9.5 7.5 7.6 11.7 5.7 5.2 9.2 6.2 4.1 11.9 10.7 1.9 7.0 0.9 5.5 12.7 10.1 9.1 2.5 14.2 4.9 4.0 10.9 11.2 8.4 5.7 14.7 12.1 8.5 7.7 3.3 13.2 10.0 6.1 8.8 3.5 1.6 8.7 7.1 7.2 14.0 5.0 5.6 5.2 8.0 17.6 6.1 8.9 9.8 9.2 2.3 7.0 7.6 7.3 9.8 0.0 7.0 11.6 4.5 1.5 5.9 3.7 3.6 7.7 10.1 6.7 1.4 THAP7 MGC10963 ENSG00000184436 "THAP domain containing 7" Q9BT49 22 20999104-21002196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.9;Spermatogonia: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 106.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003083 Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Vesicles" "HPA003083: AB_1080264" "unprognostic (6.48e-2)" "unprognostic (2.13e-3)" "unprognostic (3.28e-1)" "unprognostic (4.89e-3)" "unprognostic (1.92e-2)" "unprognostic (1.82e-3)" "unprognostic (5.56e-2)" "unprognostic (1.40e-2)" "unprognostic (2.82e-1)" "unprognostic (2.74e-3)" "unprognostic (1.27e-3)" "unprognostic (2.23e-2)" "unprognostic (9.15e-2)" "unprognostic (2.29e-2)" "unprognostic (1.83e-1)" "unprognostic (3.72e-2)" "unprognostic (3.51e-3)" 16.1 26.9 13.7 5.6 12.9 4.8 18.1 13.7 19.6 23.0 16.0 23.1 7.9 20.4 4.8 15.4 20.9 5.8 19.4 12.6 13.2 20.8 37.8 13.4 8.8 14.1 14.9 21.9 26.9 9.8 39.5 4.2 14.4 29.1 2.5 2.7 19.0 9.2 39.7 19.1 19.0 3.5 13.3 24.2 23.2 35.5 13.9 7.6 20.9 14.4 3.7 21.5 16.6 13.2 23.5 25.0 6.9 11.8 6.0 7.5 14.2 12.1 11.6 15.9 14.7 11.5 13.5 17.2 11.9 7.6 8.4 16.4 6.1 12.1 2.4 17.1 36.4 21.6 18.7 14.9 18.5 22.2 13.4 7.2 15.0 14.0 12.9 7.0 8.4 13.1 106.2 19.8 8.8 29.3 24.4 13.7 9.6 16.0 24.7 19.0 13.6 10.4 8.4 11.8 13.5 11.7 15.1 19.5 21.5 3.2 22.4 14.6 5.5 25.4 19.5 15.4 12.8 27.6 17.4 14.1 27.6 14.3 22.4 1.9 22.1 8.8 27.2 23.9 36.1 50.0 32.8 27.4 21.3 36.9 45.2 36.3 1.9 24.0 25.3 31.6 30.7 24.9 13.7 12.9 13.7 19.6 12.6 13.2 14.1 14.9 14.4 13.3 13.9 13.2 18.7 16.0 25.7 6.2 33.3 19.1 20.3 24.5 14.8 31.5 25.0 30.4 14.8 37.1 18.3 25.8 14.6 31.2 23.8 22.4 64.6 28.2 30.0 16.6 15.7 20.3 22.2 16.2 5.8 38.2 30.1 25.8 20.4 10.6 21.5 21.0 18.5 35.3 27.8 13.5 5.8 22.8 30.5 15.8 11.5 44.0 41.7 14.2 40.9 1.0 27.5 52.0 45.3 3.5 7.2 23.9 19.7 32.4 28.6 31.4 38.4 57.4 22.6 27.1 39.5 22.8 43.5 162.9 119.4 16.7 16.3 29.6 28.8 31.1 21.7 13.2 P2RX6 "MGC129625, P2RXL1, P2X6, P2XM" ENSG00000099957 "Purinergic receptor P2X 6" O15547 22 21009808-21028830 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.4;skeletal muscle: 12.4;tongue: 7.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.6;Excitatory neurons: 8.9;Inhibitory neurons: 7.9;Ionocytes: 8.2;Skeletal myocytes: 20.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.7;LHCN-M2: 6.7;RH-30: 4.2;U-87 MG: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028776, HPA028777" Approved Approved Nucleoli,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoli, Cytosol" "HPA028776: AB_2672771, HPA028777: AB_2672772" "unprognostic (1.81e-2)" "unprognostic (5.15e-3)" "unprognostic (2.11e-2)" "unprognostic (1.12e-1)" "unprognostic (4.28e-2)" "unprognostic (1.79e-5)" "unprognostic (1.70e-2)" "unprognostic (6.20e-2)" "unprognostic (1.49e-1)" "unprognostic (2.59e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-2)" "unprognostic (2.88e-10)" "unprognostic (2.81e-1)" "unprognostic (1.38e-1)" "unprognostic (7.33e-2)" "unprognostic (2.39e-3)" 0.3 1.1 0.0 0.3 0.2 0.0 0.1 1.0 2.6 0.1 0.4 0.1 0.0 0.2 0.0 0.2 0.3 0.8 1.3 1.0 1.5 0.2 0.1 0.3 0.2 3.4 0.4 0.3 0.1 0.0 1.3 0.8 3.4 0.3 0.0 0.3 0.2 0.7 12.4 0.1 0.1 0.1 0.1 1.6 0.2 1.1 0.6 0.0 0.0 7.7 0.0 0.2 0.1 1.2 0.0 0.4 0.7 0.2 0.1 0.0 0.8 0.1 1.7 0.7 1.2 0.0 0.0 0.0 1.1 0.4 2.9 1.3 0.0 0.1 0.1 0.2 0.0 1.9 0.9 0.0 2.8 0.0 2.4 0.3 0.0 1.2 0.0 9.7 0.0 0.0 2.1 0.6 6.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.2 0.2 0.0 0.0 0.2 3.1 1.2 0.1 0.5 0.1 0.0 0.0 0.0 2.1 0.3 0.0 0.0 0.2 0.0 0.0 11.7 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 2.6 1.0 1.5 3.4 0.4 3.4 0.1 0.6 1.2 0.2 0.0 0.6 0.3 0.1 0.1 0.8 0.8 0.6 7.6 0.0 0.4 2.4 0.0 0.2 1.8 0.0 0.5 0.0 0.1 0.0 0.0 2.2 1.8 0.5 0.2 3.5 2.7 8.9 0.0 0.4 1.4 0.0 0.7 2.5 0.1 1.8 0.1 0.1 1.7 7.9 0.7 8.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 5.0 3.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 3.2 1.1 0.0 20.8 0.4 1.6 0.4 0.3 0.1 0.4 0.5 0.1 0.1 0.2 SLC7A4 "CAT-4, HCAT3, VH" ENSG00000099960 "Solute carrier family 7 member 4" O43246 22 21028718-21032840 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 21.2;Endometrial ciliated cells: 16.4;Glandular and luminal cells: 32.0;Intestinal goblet cells: 8.9;Ionocytes: 12.2;Syncytiotrophoblasts: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "BEWO: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031023 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA031023: AB_10669669" "unprognostic (1.02e-3)" "unprognostic (4.34e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (3.82e-2)" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.91e-2)" "unprognostic (3.68e-2)" "unprognostic (2.51e-2)" "unprognostic (2.58e-2)" "unprognostic (1.21e-3)" "unprognostic (9.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.62e-1)" "unprognostic (1.32e-2)" "unprognostic (4.00e-3)" 2.7 2.6 3.1 0.2 2.6 0.0 1.0 3.8 2.8 1.5 4.5 1.1 1.0 1.0 0.3 5.6 1.1 1.3 1.1 2.3 3.8 0.4 0.3 0.8 0.3 1.8 2.6 0.3 0.2 0.5 4.7 3.3 4.5 2.5 0.9 0.3 2.2 3.2 0.4 1.6 1.2 0.3 0.3 0.5 1.4 15.4 4.8 0.3 0.0 0.0 0.5 1.1 0.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 140.5 0.0 0.0 0.3 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 1.3 0.5 0.3 0.0 0.1 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 3.1 2.6 3.8 2.8 2.3 3.8 1.8 2.6 4.5 0.3 4.8 0.7 0.0 6.4 1.9 0.3 0.0 0.0 0.3 7.4 0.6 0.5 0.7 0.6 0.3 1.5 3.1 0.0 0.0 21.2 0.0 0.5 0.0 0.0 0.3 16.4 2.1 0.3 1.2 0.0 1.4 0.4 7.7 2.0 1.1 32.0 4.5 0.7 1.1 0.0 1.4 0.0 0.8 8.9 12.2 0.0 0.0 1.8 1.8 0.1 0.0 1.0 0.0 2.0 0.0 0.0 0.1 0.8 0.3 0.7 0.0 0.5 0.3 0.0 2.6 0.1 0.0 0.3 0.4 0.3 1.5 1.8 0.0 10.1 0.7 0.0 0.6 0.6 LRRC74B ENSG00000187905 "Leucine rich repeat containing 74B" Q6ZQY2 22 21045960-21064168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;choroid plexus: 4.0;fallopian tube: 3.8" "Cell type enhanced" "Detected in some" "Club cells: 12.4;Endometrial ciliated cells: 25.8;Respiratory ciliated cells: 72.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049947 Uncertain NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "HPA049947: AB_2680966" "unprognostic (3.43e-2)" "unprognostic (1.76e-1)" "unprognostic (3.28e-4)" "unprognostic (1.06e-1)" "unprognostic (6.44e-3)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.64e-2)" "unprognostic (1.18e-1)" "unprognostic (7.57e-9)" "unprognostic (4.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-2)" "unprognostic (4.92e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.6 4.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.9 0.0 0.0 1.0 0.0 1.2 1.7 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.9 1.2 1.7 0.5 1.4 0.1 0.3 0.1 0.0 1.8 2.9 0.1 0.0 0.7 0.0 0.0 1.1 0.3 0.5 0.6 0.0 12.4 0.0 4.2 0.2 0.5 0.0 0.0 0.0 3.7 25.8 0.5 0.5 0.0 0.0 2.0 0.0 0.1 0.7 0.0 0.9 0.0 0.1 0.4 0.4 0.1 1.7 0.6 0.0 0.0 0.0 0.0 1.0 0.3 0.8 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 72.1 1.5 0.0 2.5 0.4 4.6 3.1 0.0 0.0 0.3 0.4 0.5 0.1 0.1 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FAM246A ENSG00000286102 "Family with sequence similarity 246 member A" A0A494C0Y3 22 21360601-21361299 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 10 "brain: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.1 0.8 0.1 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383374-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 49 "brain: 41.3;choroid plexus: 18.4;testis: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RH-30: 1.1;THP-1: 2.1" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (3.78e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.28e-1)" "unprognostic (5.35e-2)" "unprognostic (4.37e-1)" "unprognostic (3.61e-4)" "unprognostic (1.69e-2)" "unprognostic (7.11e-2)" 0.0 0.1 8.2 0.4 12.8 0.0 0.0 41.3 19.1 0.0 18.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 10.4 13.6 0.0 0.0 0.1 0.3 16.5 12.6 0.0 0.1 0.2 0.0 0.2 19.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 16.2 0.2 0.0 13.6 13.2 0.4 0.1 0.0 0.2 0.0 0.0 29.6 0.0 0.5 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.2 0.2 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.2 0.9 1.2 0.1 0.2 0.1 0.8 1.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 8.2 12.8 41.3 19.1 10.4 13.6 16.5 12.6 19.2 16.2 13.2 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HIC2 "HRG22, KIAA1020, ZBTB30, ZNF907" ENSG00000169635 "HIC ZBTB transcriptional repressor 2" Q96JB3 22 21417371-21451463 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.6;Extravillous trophoblasts: 41.4;Syncytiotrophoblasts: 39.5" "Cancer enriched" "Detected in all" 5 "testis cancer: 17.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 69.2;K-562: 126.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031884, HPA059399" Uncertain Supported Nucleoplasm NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA031884: AB_10602234, HPA059399: AB_2684003" "unprognostic (2.37e-1)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (7.42e-5)" "unprognostic (1.83e-1)" "unprognostic (3.83e-1)" "unprognostic (3.62e-2)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-2)" "unprognostic (1.21e-4)" "unprognostic (1.28e-1)" "unprognostic (4.83e-3)" "unprognostic (7.34e-3)" "unprognostic (3.33e-1)" "unprognostic (3.86e-2)" "unprognostic (5.64e-2)" 2.2 1.2 2.5 1.4 2.6 3.7 1.5 0.8 2.8 1.7 0.0 2.1 1.3 2.0 0.5 2.6 2.2 0.8 1.5 2.7 0.9 1.7 1.8 1.8 1.5 1.0 0.6 3.4 2.1 1.1 2.6 5.8 0.9 1.2 0.8 1.5 1.4 0.7 1.1 1.5 2.1 0.7 0.2 2.4 2.4 7.4 1.0 1.7 2.4 1.1 0.9 1.1 1.5 1.4 2.2 2.7 14.4 4.3 1.1 0.9 69.2 1.4 0.5 1.4 1.2 27.2 0.8 5.1 1.4 0.9 0.9 5.9 10.2 0.9 0.8 3.4 15.0 6.8 4.0 15.0 1.2 6.0 3.1 1.1 0.5 2.1 0.9 0.7 1.1 2.1 126.9 2.1 0.7 2.1 2.7 6.2 15.3 4.8 2.0 6.7 6.4 0.8 0.7 3.6 4.0 7.0 1.8 2.1 2.6 14.9 1.2 9.0 1.9 2.2 5.4 2.1 1.6 4.2 3.6 5.4 1.8 2.5 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.3 0.0 0.0 2.5 2.6 0.8 2.8 2.7 0.9 1.0 0.6 0.9 0.2 1.0 1.4 10.3 3.2 1.1 3.6 7.7 5.5 5.4 2.6 23.9 14.8 4.7 4.2 3.9 7.2 1.7 1.8 14.6 39.6 4.4 10.0 0.0 2.6 14.2 8.3 7.6 6.5 6.1 5.7 11.8 2.6 41.4 6.6 11.2 7.6 1.3 6.4 2.9 3.0 10.3 8.4 7.5 7.4 6.1 3.8 4.3 29.9 5.6 5.6 5.4 1.9 4.5 3.0 2.1 5.0 2.3 2.8 4.6 10.1 10.4 8.1 7.0 1.6 1.5 7.3 6.6 10.7 6.0 12.2 24.5 27.1 4.5 39.5 5.8 2.6 9.3 7.5 TMEM191C ENSG00000206140 "Transmembrane protein 191C" A6NGB0 22 21466423-21471269 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 36 "testis: 50.7" "Group enriched" "Detected in many" 19 "Early spermatids: 841.3;Late spermatids: 1024.5" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "CACO-2: 1.0" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.55e-1)" "unprognostic (2.18e-2)" "unprognostic (7.12e-3)" "unprognostic (2.83e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-1)" "unprognostic (1.77e-2)" "unprognostic (5.97e-2)" "unprognostic (1.25e-1)" "unprognostic (2.40e-2)" "unprognostic (1.59e-3)" "unprognostic (2.09e-1)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (7.63e-2)" "unprognostic (1.36e-1)" "unprognostic (4.12e-3)" 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.4 0.0 0.4 0.0 0.1 0.0 1.4 0.3 0.0 0.2 0.0 0.1 0.8 0.6 0.4 0.0 0.0 0.1 0.2 0.2 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.7 0.3 0.0 0.0 0.8 0.3 50.7 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.7 0.0 0.1 2.4 0.6 0.2 0.2 0.6 0.2 0.9 1.4 0.3 0.4 0.4 3.4 0.2 0.2 0.6 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 2.3 0.7 9.3 5.0 1.6 5.6 5.2 3.3 4.4 6.7 0.7 4.3 2.4 5.5 2.1 48.2 8.3 21.5 0.0 2.8 841.3 5.3 0.5 1.9 10.2 0.8 2.6 0.2 22.5 2.3 9.7 2.0 7.0 0.8 1.1 4.2 10.1 13.5 2.4 8.7 4.1 8.4 8.0 1024.5 5.3 6.5 3.6 0.0 6.3 1.0 11.3 0.0 0.5 4.3 17.2 4.1 3.3 1.5 28.0 8.0 4.9 2.4 0.0 1.3 2.8 10.0 8.7 9.2 6.8 19.0 8.7 2.1 7.3 1.0 RIMBP3C ENSG00000183246 "RIMS binding protein 3C" A6NJZ7 22 21545678-21551461 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 6.1" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Late spermatids: 49.4;Spermatocytes: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (8.30e-2)" "unprognostic (4.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.15e-3)" "unprognostic (6.23e-2)" "unprognostic (2.17e-6)" "unprognostic (3.04e-1)" "unprognostic (3.29e-1)" "unprognostic (3.76e-6)" "unprognostic (1.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.6 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UBE2L3 UBCH7 ENSG00000185651 "Ubiquitin conjugating enzyme E2 L3" P68036 22 21549447-21624034 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 544.4" "HPA045609, HPA062415" Approved Approved Nucleoplasm,Cytosol NA NA 5800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cytosol" "HPA045609: AB_10961322, HPA062415: AB_2684756" "unprognostic (4.90e-2)" "unprognostic (3.05e-1)" "unprognostic (1.92e-2)" "unprognostic (1.07e-2)" "unprognostic (2.74e-2)" "unprognostic (9.99e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "prognostic favorable (3.82e-6)" "unprognostic (3.53e-2)" "unprognostic (4.55e-2)" "unprognostic (3.18e-2)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (2.77e-1)" "unprognostic (3.15e-3)" 41.5 46.0 63.7 37.1 64.8 54.4 33.9 65.0 72.0 35.5 54.4 45.5 39.6 35.0 41.0 49.1 38.5 34.0 51.5 65.4 65.3 40.1 40.9 33.9 48.8 67.8 64.7 33.9 30.3 43.2 31.2 42.7 66.8 39.1 45.6 28.1 33.9 36.8 63.5 36.2 40.7 48.6 62.3 37.6 37.5 28.5 66.7 51.9 36.4 53.1 52.5 46.8 32.3 65.5 121.9 68.9 98.3 77.4 105.1 93.1 56.6 100.0 113.6 125.8 118.7 79.0 57.0 114.2 49.0 133.5 94.7 101.4 132.1 108.6 124.3 114.4 142.9 132.1 63.3 94.8 70.0 190.9 91.0 82.7 93.1 91.2 65.7 90.6 143.4 69.4 544.4 59.3 137.9 89.6 100.0 137.6 72.8 134.8 71.6 80.5 147.6 31.2 118.8 96.2 88.0 65.4 79.9 99.1 95.6 89.4 61.7 104.0 103.8 88.6 113.5 75.5 103.6 57.3 99.7 103.7 120.0 87.5 86.0 84.4 87.8 105.7 84.9 102.2 79.7 77.3 79.9 91.6 109.2 73.6 69.0 82.9 73.2 81.2 89.0 106.3 106.1 141.1 63.7 64.8 65.0 72.0 65.4 65.3 67.8 64.7 66.8 62.3 66.7 65.5 102.6 109.0 83.9 26.1 110.7 125.5 171.6 318.5 51.2 54.5 76.9 72.8 64.9 101.5 180.3 71.7 16.7 312.1 159.0 215.1 197.6 288.2 79.9 133.1 104.6 125.9 126.0 173.0 25.6 385.0 406.5 102.6 60.1 124.9 129.3 79.3 109.6 159.8 298.5 69.0 24.3 153.1 193.3 126.9 159.7 61.1 87.3 140.9 126.3 19.7 257.9 98.4 200.8 22.6 30.4 432.1 222.1 103.8 98.4 186.7 213.5 257.2 173.9 45.5 105.2 81.0 205.4 202.8 121.2 87.6 129.7 372.1 130.1 133.7 154.0 208.4 YDJC ENSG00000161179 "YdjC chitooligosaccharide deacetylase homolog" A8MPS7 22 21628089-21630064 "Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061005 Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "HPA061005: AB_2684412" "unprognostic (5.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.96e-1)" "unprognostic (2.29e-1)" "unprognostic (2.31e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (9.84e-4)" "unprognostic (9.35e-2)" "unprognostic (7.08e-2)" "unprognostic (8.09e-3)" "unprognostic (1.24e-1)" "unprognostic (9.86e-2)" "unprognostic (4.90e-3)" "unprognostic (1.07e-1)" "unprognostic (2.25e-1)" "unprognostic (9.60e-2)" "prognostic favorable (8.98e-5)" 2.2 4.1 4.3 1.2 4.2 0.7 2.8 3.8 7.5 3.5 3.7 4.4 1.9 4.0 1.6 7.2 4.4 0.3 2.8 4.3 3.9 8.0 6.6 2.8 0.5 4.7 4.1 3.8 9.7 1.4 3.3 0.5 4.3 4.9 1.2 0.4 4.6 1.5 2.0 5.7 4.9 0.8 4.1 5.0 5.6 3.2 4.1 0.6 6.1 0.0 2.6 4.6 4.3 4.7 8.3 1.5 0.1 1.2 2.4 1.8 8.8 3.5 2.5 2.7 3.7 0.7 3.5 7.4 12.6 0.9 1.9 6.8 5.0 8.3 4.5 6.5 23.8 9.7 1.5 12.3 4.2 18.7 8.5 3.5 13.1 2.4 21.1 2.6 5.9 10.0 82.4 1.5 2.3 10.5 6.7 30.5 3.0 23.8 13.8 4.7 0.0 8.2 15.4 4.5 11.0 6.1 3.1 6.3 6.3 1.6 6.7 10.3 4.9 0.9 8.9 1.9 4.3 12.8 7.4 5.7 1.0 6.0 1.6 8.1 14.4 12.4 9.4 14.5 9.9 18.3 13.6 10.1 18.0 18.4 11.4 10.4 5.3 22.3 9.4 11.2 15.3 11.1 4.3 4.2 3.8 7.5 4.3 3.9 4.7 4.1 4.3 4.1 4.1 4.7 11.8 6.4 8.2 1.0 39.4 25.0 54.1 35.0 22.2 5.8 27.1 28.2 3.6 18.6 15.3 44.1 0.0 43.1 30.3 24.9 39.2 57.7 25.3 15.2 10.1 13.0 16.2 19.1 5.4 42.8 69.1 11.6 15.8 15.8 12.0 27.9 5.0 15.0 30.2 3.3 4.6 33.5 22.4 15.7 22.9 4.8 10.5 16.3 14.2 1.9 53.9 8.6 27.8 1.5 5.3 51.4 44.5 6.8 21.1 88.9 52.0 68.3 11.3 5.6 19.7 3.7 10.7 27.7 26.3 26.6 22.7 23.1 28.9 32.6 38.9 45.7 CCDC116 FLJ36046 ENSG00000161180 "Coiled-coil domain containing 116" Q8IYX3 22 21632716-21637329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "testis: 29.7" "Group enriched" "Detected in some" 40 "Early spermatids: 224.6;Late spermatids: 169.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.1;JURKAT: 5.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (7.01e-2)" "unprognostic (6.01e-4)" "unprognostic (1.04e-1)" "unprognostic (6.85e-3)" "unprognostic (1.34e-2)" "unprognostic (1.15e-1)" "unprognostic (1.67e-2)" "unprognostic (5.13e-2)" "unprognostic (2.01e-1)" "unprognostic (4.75e-2)" "unprognostic (1.37e-3)" "unprognostic (4.14e-1)" "unprognostic (5.79e-4)" "unprognostic (1.82e-1)" "unprognostic (3.13e-2)" "unprognostic (2.47e-2)" "unprognostic (8.64e-2)" 0.8 0.2 0.5 0.2 0.4 0.2 0.8 0.5 0.7 1.3 0.0 1.0 0.1 1.2 0.2 0.3 0.8 0.2 0.6 0.3 0.3 0.5 0.3 0.6 0.3 0.4 0.3 1.1 0.4 0.1 0.4 0.5 0.3 1.0 0.2 0.1 0.4 0.4 0.3 0.5 0.6 0.1 0.1 0.7 0.5 29.7 0.5 0.1 0.8 0.0 0.1 0.8 0.8 0.5 0.1 0.0 0.2 0.5 0.3 0.0 0.6 0.7 0.0 0.3 0.1 0.0 0.2 0.4 0.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.3 0.1 0.3 0.1 0.0 0.0 3.1 0.0 0.0 0.2 0.0 0.0 0.0 5.3 1.3 0.1 0.1 1.1 1.2 0.1 0.0 0.0 0.1 0.4 0.5 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.2 0.0 1.0 1.1 0.3 0.1 1.3 0.8 0.1 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.5 0.7 0.3 0.3 0.4 0.3 0.3 0.1 0.5 0.5 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.1 224.6 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.2 169.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 4.9 1.3 0.0 0.0 0.3 0.1 0.0 0.1 0.1 SDF2L1 "AP000553.C22.4, OTTHUMT00000075032" ENSG00000128228 "Stromal cell derived factor 2 like 1" Q9HCN8 22 21642302-21644299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.0" "Cell type enhanced" "Detected in all" "Plasma cells: 646.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 330.5" "Low region specificity" "Detected in all" HPA005638 Approved "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" "HPA005638: AB_1079888" "unprognostic (1.09e-1)" "unprognostic (2.76e-2)" "unprognostic (6.17e-2)" "prognostic favorable (4.98e-5)" "unprognostic (8.81e-3)" "unprognostic (2.29e-1)" "unprognostic (9.20e-2)" "unprognostic (2.30e-1)" "unprognostic (4.92e-2)" "unprognostic (6.88e-3)" "unprognostic (1.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.63e-2)" "unprognostic (3.44e-1)" "unprognostic (1.55e-1)" "unprognostic (1.70e-1)" "unprognostic (2.79e-2)" 28.5 40.4 14.0 31.1 15.1 25.8 23.6 15.9 18.8 25.0 22.2 36.3 24.9 33.0 21.7 30.9 29.8 5.7 41.0 14.3 20.7 43.8 170.0 35.9 16.9 19.0 16.2 16.0 94.6 10.0 77.3 11.7 16.0 32.7 9.8 1.4 48.0 11.5 17.3 19.5 35.7 7.1 16.2 68.2 40.9 35.0 17.0 9.6 89.9 1.7 11.9 33.2 21.5 17.2 77.3 64.6 15.9 53.4 9.2 11.9 99.6 66.5 16.6 31.4 34.5 66.8 44.9 70.1 59.4 16.0 50.7 62.2 29.8 45.9 8.5 51.4 179.7 53.3 70.1 147.5 52.8 53.7 89.6 8.9 19.6 29.4 30.6 10.9 31.1 37.1 330.5 175.8 13.4 146.4 52.8 76.4 17.6 82.8 110.3 48.6 36.4 58.9 22.2 57.0 33.8 52.2 33.6 56.8 36.5 12.5 54.5 62.9 35.9 16.6 92.1 55.7 41.4 160.6 70.7 52.0 32.7 62.1 49.8 114.0 98.9 44.6 173.3 106.8 130.2 131.8 109.2 156.8 72.6 124.9 86.5 102.7 29.8 101.0 102.2 218.5 126.9 106.3 14.0 15.1 15.9 18.8 14.3 20.7 19.0 16.2 16.0 16.2 17.0 17.2 52.3 25.6 28.5 2.6 164.7 114.2 125.1 89.0 16.5 5.6 80.2 57.8 35.8 62.9 50.3 49.7 35.5 94.7 98.0 194.2 25.4 121.2 52.3 59.3 47.7 58.0 186.1 51.1 1.5 177.5 342.9 64.6 53.0 65.0 111.3 19.0 61.4 286.2 224.1 5.0 2.2 344.8 48.8 68.7 205.4 31.4 32.3 85.9 211.7 6.5 69.4 62.0 145.2 4.0 4.6 175.5 169.6 16.6 646.4 203.8 129.8 96.5 40.9 13.0 39.5 26.2 53.0 276.5 218.9 23.9 112.5 168.1 85.1 37.5 188.1 129.4 PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666000-21700015 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "K-562: 190.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA035344: AB_10672863, HPA055637: AB_2682869" "unprognostic (1.97e-3)" "unprognostic (3.61e-2)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (2.90e-3)" "unprognostic (5.16e-3)" "unprognostic (3.77e-2)" "unprognostic (9.46e-2)" "unprognostic (1.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.89e-2)" "unprognostic (2.45e-3)" "unprognostic (5.46e-2)" "unprognostic (5.39e-2)" "unprognostic (5.39e-2)" "unprognostic (1.54e-3)" 8.9 14.2 4.7 12.8 5.7 6.3 9.5 4.0 7.0 11.6 2.1 12.1 8.1 12.0 9.3 16.4 10.7 9.5 13.9 5.8 4.8 12.6 15.0 10.1 16.4 3.5 2.9 10.7 19.2 16.4 14.3 9.1 3.9 12.4 10.6 9.0 14.7 9.5 18.8 12.3 13.3 9.9 3.6 14.0 13.9 10.1 3.1 15.8 18.8 13.0 16.4 11.7 12.1 4.8 20.4 17.1 18.1 20.1 19.2 17.6 15.8 19.3 17.9 28.0 24.5 21.3 10.3 34.0 12.7 27.2 13.9 22.9 28.6 23.6 16.2 19.2 28.2 26.7 14.2 32.4 14.7 42.5 21.5 17.4 21.2 19.4 14.0 15.1 25.1 18.5 190.3 17.9 19.6 28.6 20.5 13.7 20.2 35.7 14.9 23.7 31.1 5.7 14.2 14.1 30.8 18.4 21.2 32.7 9.7 11.3 27.1 20.3 27.5 15.8 25.1 17.5 12.7 19.2 17.5 24.7 21.6 22.6 24.9 1.5 9.7 5.1 9.6 15.3 12.2 7.2 11.5 12.6 13.7 8.3 10.5 9.4 2.3 14.1 22.6 11.9 15.6 12.1 4.7 5.7 4.0 7.0 5.8 4.8 3.5 2.9 3.9 3.6 3.1 4.8 9.8 9.6 29.5 15.0 21.5 3.2 7.9 10.9 10.8 26.3 13.4 10.2 5.7 27.1 16.6 14.7 33.3 15.8 39.4 23.9 13.7 12.8 66.8 15.4 14.8 8.0 11.4 17.7 19.9 16.7 13.3 10.3 39.3 19.5 17.1 16.6 10.4 18.9 15.3 18.5 24.2 20.6 14.2 21.0 5.3 90.9 12.2 15.5 1.8 8.4 16.6 11.5 52.5 12.5 17.4 18.5 17.4 13.5 23.8 10.9 14.2 9.1 11.9 31.4 0.0 11.2 9.4 23.6 17.3 12.3 5.7 22.2 24.5 14.8 20.8 12.6 YPEL1 ENSG00000100027 "Yippee like 1" O60688 22 21697536-21735794 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 29.9;testis: 77.9" "Group enriched" "Detected in many" 9 "Early spermatids: 706.3;Late spermatids: 1354.3;Spermatocytes: 394.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 18.8;JURKAT: 38.0;MOLT-4: 20.4;REH: 22.1;SCLC-21H: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030501, HPA045621" Uncertain NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA030501: AB_10602683, HPA045621: " "unprognostic (1.36e-1)" "unprognostic (2.47e-3)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.09e-5)" "unprognostic (3.82e-3)" "unprognostic (1.06e-4)" "unprognostic (1.44e-1)" "unprognostic (1.10e-2)" "unprognostic (2.38e-1)" "unprognostic (1.61e-1)" "unprognostic (4.68e-3)" "unprognostic (2.06e-1)" "unprognostic (1.27e-1)" "unprognostic (6.03e-2)" "unprognostic (1.55e-1)" "unprognostic (2.51e-2)" "unprognostic (5.16e-3)" 3.3 2.3 13.2 2.9 29.9 6.4 3.3 8.9 16.6 2.0 8.1 3.3 2.4 4.1 1.6 2.0 2.7 3.1 7.2 17.4 13.3 2.4 2.5 5.5 5.8 4.8 6.2 7.6 3.9 3.3 2.6 1.3 5.6 2.7 1.8 3.7 2.7 1.2 15.7 1.7 2.5 2.4 4.6 8.4 3.4 77.9 14.4 14.6 2.7 6.4 4.5 2.1 1.3 9.4 2.1 0.4 18.8 11.6 1.4 0.6 1.0 0.7 0.2 1.3 1.8 0.0 1.0 3.1 2.4 0.3 1.7 0.2 1.1 0.3 1.1 9.6 3.3 0.2 0.3 0.9 1.1 2.1 2.4 1.3 0.3 0.5 0.2 3.3 3.2 38.0 1.2 10.1 1.8 0.5 20.4 5.0 1.1 0.3 2.9 22.1 4.7 1.2 0.4 0.1 19.2 13.6 2.3 2.2 1.5 3.7 1.1 2.7 1.8 0.3 5.0 0.4 0.7 13.9 7.2 10.7 1.1 2.2 3.1 0.2 0.1 0.1 1.9 0.4 1.5 0.3 0.3 1.8 0.2 0.6 0.1 0.9 0.8 2.4 0.1 1.7 0.8 0.5 13.2 29.9 8.9 16.6 17.4 13.3 4.8 6.2 5.6 4.6 14.4 9.4 6.3 3.2 4.8 13.7 9.1 1.8 2.9 0.5 0.6 6.8 6.4 3.8 4.8 7.2 2.1 3.7 6.2 0.6 62.1 0.6 0.0 7.1 706.3 6.1 3.1 6.4 13.1 10.3 16.7 3.5 0.4 3.6 2.6 3.6 0.0 23.0 10.4 6.7 1.6 6.7 11.6 1.8 0.0 3.2 3.7 1354.3 11.5 4.9 0.0 8.4 2.9 4.7 90.6 9.0 7.6 3.9 0.3 10.9 12.5 3.4 0.2 4.2 2.3 7.5 13.1 8.4 4.3 394.7 12.0 0.5 1.8 1.4 20.6 1.7 2.6 2.4 MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 341.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079930, CAB079932, CAB079933" Enhanced Supported "Nuclear speckles,Cytosol" NA NA 140000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nuclear speckles" "CAB004229: AB_627547, CAB079930: , CAB079932: , CAB079933: , HPA003995: AB_1078751, HPA005700: AB_1078750, HPA030069: AB_10602035" "unprognostic (9.41e-3)" "unprognostic (2.68e-1)" "unprognostic (2.50e-3)" "unprognostic (4.17e-1)" "unprognostic (4.44e-3)" "unprognostic (1.72e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (2.29e-1)" "unprognostic (1.67e-1)" "unprognostic (1.58e-1)" "unprognostic (8.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.35e-2)" "unprognostic (2.08e-1)" "unprognostic (1.94e-1)" "unprognostic (1.41e-1)" "unprognostic (6.49e-2)" 31.1 33.1 64.8 35.9 84.4 41.2 29.8 37.3 80.9 31.4 32.9 36.1 25.8 29.6 30.1 43.0 29.0 28.9 42.2 91.3 46.4 42.1 34.2 38.5 36.8 29.1 45.1 29.2 38.1 51.7 12.0 33.1 35.9 32.8 36.2 30.3 28.9 32.7 38.1 45.0 29.5 39.1 43.8 40.5 33.9 43.7 60.1 44.4 46.1 41.9 41.9 35.5 18.9 43.2 78.7 48.0 60.5 37.2 75.9 76.7 25.9 84.7 77.5 73.2 72.0 43.8 40.8 45.8 41.3 112.7 67.5 74.6 73.9 67.9 97.8 180.4 72.1 78.9 43.0 67.7 73.5 113.2 80.5 56.9 60.1 89.4 81.6 58.0 101.7 45.4 341.9 50.5 97.5 36.6 72.0 38.5 24.4 104.5 46.8 79.4 149.6 13.2 55.5 62.9 50.0 28.6 91.5 64.2 57.2 60.4 42.4 47.1 90.1 61.5 79.6 71.9 54.2 47.1 59.4 65.8 60.0 60.0 68.4 1.4 4.9 7.2 15.9 6.0 4.9 2.3 3.6 6.0 4.1 2.6 3.5 6.1 16.5 9.3 6.9 4.0 3.4 4.0 64.8 84.4 37.3 80.9 91.3 46.4 29.1 45.1 35.9 43.8 60.1 43.2 36.8 48.1 35.8 97.6 44.0 60.2 28.4 25.1 28.5 25.5 32.5 24.5 41.5 42.9 31.2 51.5 54.2 21.8 151.7 74.4 19.6 28.5 49.0 33.5 40.3 39.9 59.6 63.8 109.2 39.2 23.2 38.4 52.0 45.0 92.8 28.8 52.1 63.5 53.2 28.6 91.2 42.2 26.4 89.0 77.1 14.7 32.6 74.9 40.9 68.4 75.0 35.8 143.2 82.4 75.1 45.3 35.2 44.4 37.0 43.8 32.8 46.0 32.2 22.4 32.9 44.6 37.3 74.1 53.4 44.9 61.8 19.2 91.4 43.3 38.6 38.8 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 42.2;Hepatic stellate cells: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.6" "Group enriched" "Detected in all" 7 "dendritic cells: 8.9;granulocytes: 28.6;monocytes: 24.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 109.1;K-562: 173.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 510000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 24.1 18.1 14.9 21.6 13.9 26.8 17.6 11.6 15.7 18.5 11.8 17.1 8.9 19.9 3.8 22.1 15.0 12.2 16.8 14.5 19.4 18.4 8.0 26.1 15.2 16.8 16.4 12.5 12.3 6.4 8.5 26.6 17.3 15.8 4.2 3.7 10.9 14.3 17.0 14.8 13.8 12.1 15.3 35.8 12.0 6.3 17.1 7.8 12.4 10.5 7.8 22.0 15.9 15.4 28.9 30.1 19.0 18.6 10.4 18.1 23.9 32.1 18.9 27.7 19.0 13.8 11.3 17.3 39.0 22.7 11.8 33.9 8.3 19.9 9.8 24.7 27.1 66.8 14.5 13.2 17.1 25.0 17.4 17.1 5.9 27.1 12.6 19.6 109.1 16.9 173.4 7.2 35.9 26.2 15.0 19.3 8.0 9.2 32.7 21.9 49.0 5.2 9.4 12.1 7.7 29.6 30.4 10.0 25.7 7.4 12.5 17.2 93.1 33.1 33.4 30.5 31.1 14.1 12.2 19.6 33.5 46.7 64.7 0.0 12.8 5.9 1.7 21.0 1.0 1.1 1.1 0.9 8.9 0.9 1.0 1.3 28.6 3.1 24.4 2.2 2.4 5.4 14.9 13.9 11.6 15.7 14.5 19.4 16.8 16.4 17.3 15.3 17.1 15.4 32.1 6.4 6.0 11.8 5.5 8.2 5.2 4.9 8.6 8.3 7.4 9.9 11.9 8.6 4.1 1.8 2.1 16.6 5.1 1.4 3.9 5.2 2.0 3.0 9.4 42.2 6.0 5.5 11.6 5.1 10.0 8.4 3.1 3.8 3.8 10.4 56.4 6.5 20.6 8.4 12.7 4.2 6.1 37.0 22.0 1.5 7.2 23.4 7.2 18.7 30.9 4.1 6.2 12.5 6.8 7.4 1.1 6.8 5.0 7.4 2.6 4.4 4.0 6.5 6.6 17.2 8.2 14.2 13.1 8.5 5.7 3.0 6.4 7.1 4.5 6.6 TOP3B ENSG00000100038 "DNA topoisomerase III beta" O95985 22 21957025-21982813 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072114 Approved Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA072114: " "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-1)" "unprognostic (3.93e-1)" "unprognostic (2.15e-2)" "unprognostic (2.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.29e-2)" "unprognostic (1.96e-2)" "unprognostic (1.69e-2)" "unprognostic (1.21e-1)" "unprognostic (3.53e-2)" "unprognostic (1.11e-4)" 10.6 12.0 5.5 10.1 6.9 16.2 11.2 7.5 8.3 17.9 12.2 13.7 11.1 13.5 7.1 14.8 13.5 7.4 11.8 6.0 5.7 13.9 17.0 13.7 12.7 5.9 5.0 20.3 12.7 7.4 12.9 8.4 6.1 16.7 9.9 6.9 13.9 6.8 10.4 14.7 17.7 9.7 4.0 25.0 13.5 11.1 6.3 13.6 14.3 5.7 13.4 11.4 15.5 8.1 22.1 21.1 40.9 16.8 14.8 12.3 25.7 14.2 17.6 32.1 28.3 22.2 9.3 29.9 10.5 14.9 13.4 39.6 18.6 25.2 25.9 15.3 45.4 23.5 31.4 24.1 20.1 32.3 14.9 6.1 37.5 26.8 12.7 18.6 27.1 17.2 112.5 15.7 15.2 22.3 20.6 25.0 17.0 15.8 19.9 31.6 27.1 4.6 15.8 28.9 26.7 19.3 17.4 15.4 13.7 16.4 11.9 20.7 19.9 13.2 27.6 13.0 17.6 23.2 20.8 28.2 10.2 19.4 14.0 1.9 4.3 1.8 5.5 4.4 3.8 4.5 3.6 3.9 4.7 4.9 3.3 3.5 1.5 4.3 2.6 5.4 4.2 3.7 5.5 6.9 7.5 8.3 6.0 5.7 5.9 5.0 6.1 4.0 6.3 8.1 7.2 0.0 2.6 12.1 7.2 1.8 2.6 6.2 2.8 4.6 3.7 3.9 0.2 8.6 5.0 3.7 10.4 5.2 7.2 7.0 1.9 4.8 1.3 5.3 6.7 5.7 4.8 2.1 8.9 4.3 3.6 4.3 12.2 5.0 1.3 15.0 7.9 7.1 4.0 1.7 7.7 5.3 4.1 3.4 3.8 1.8 10.5 5.1 5.4 6.5 4.3 3.1 5.2 4.5 9.2 6.4 4.6 7.5 6.1 3.4 4.5 2.8 8.2 6.1 6.6 4.9 9.6 6.6 4.9 3.6 1.6 4.0 5.9 7.6 5.8 2.9 IGLV4-69 ENSG00000211637 "Immunoglobulin lambda variable 4-69" A0A075B6H9 22 22030934-22031472 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 430.3;lymphoid tissue: 461.2;salivary gland: 116.6;stomach 1: 285.6;urinary bladder: 204.0" "Cell type enriched" "Detected in some" 140 "Plasma cells: 4593.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 4 "medulla oblongata: 1.1" "Group enriched" "Detected in some" 302 "memory B-cell: 331.7;naive B-cell: 224.0" "Lineage enriched" "Detected in single" 361 "B-cells: 331.7" "Cell line enhanced" "Detected in some" "Daudi: 1.0;NB-4: 1.0;REH: 1.3;RPMI-8226: 5.4;SH-SY5Y: 1.3" "Immunoglobulin genes" NA NA 320000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.02e-4)" "unprognostic (1.32e-2)" "unprognostic (2.19e-3)" "unprognostic (1.34e-3)" "unprognostic (2.67e-2)" "prognostic favorable (4.04e-5)" "unprognostic (2.59e-3)" "unprognostic (2.50e-1)" "unprognostic (1.67e-1)" "unprognostic (5.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.89e-5)" "unprognostic (9.74e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" 15.6 9.7 0.0 172.4 0.1 43.2 64.1 0.1 0.2 27.9 0.1 325.8 430.3 5.7 0.2 52.2 5.5 44.1 15.1 0.0 0.0 6.2 14.5 72.1 450.4 1.1 0.0 10.6 8.5 0.3 1.1 0.1 0.2 6.3 209.5 0.0 116.6 6.3 0.2 0.7 219.6 3.4 0.0 305.9 285.6 1.4 0.2 82.1 9.8 0.1 461.2 204.0 5.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 1.3 0.0 5.4 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.6 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.1 331.7 0.2 0.1 0.2 224.0 0.0 0.1 0.9 0.1 0.1 0.1 0.2 32.3 0.0 0.1 0.1 0.2 0.0 0.0 1.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 11.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4593.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 IGLV10-54 ENSG00000211642 "Immunoglobulin lambda variable 10-54" A0A075B6I4 22 22038643-22215270 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 7 "breast: 121.9;intestine: 324.6;lymphoid tissue: 329.7;salivary gland: 253.6;stomach 1: 194.5" "Cell type enriched" "Detected in some" 17 "Plasma cells: 358.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 2.2" "Group enriched" "Detected in some" 32 "memory B-cell: 60.0;naive B-cell: 35.2" "Lineage enriched" "Detected in many" 41 "B-cells: 60.0" "Cell line enhanced" "Detected in single" "TIME: 2.3" "Immunoglobulin genes" NA NA 54000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (9.35e-5)" "unprognostic (2.65e-2)" "unprognostic (9.06e-2)" "unprognostic (8.71e-3)" "unprognostic (1.29e-1)" "prognostic favorable (8.30e-5)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (5.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.22e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (3.33e-1)" "unprognostic (5.57e-2)" "unprognostic (5.17e-2)" "unprognostic (3.86e-1)" 3.6 1.9 0.1 96.4 0.3 33.8 121.9 0.1 2.2 2.0 0.8 324.6 294.8 1.5 0.0 22.5 24.3 21.9 12.0 0.1 0.3 2.5 7.0 22.3 64.7 1.4 0.1 2.6 11.6 0.0 0.4 0.4 0.2 6.4 155.1 0.0 253.6 2.3 0.1 1.0 138.9 12.7 0.2 155.3 194.5 0.4 0.1 22.9 2.5 0.0 329.7 21.8 4.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 60.0 0.0 0.0 0.0 35.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 0.3 0.1 2.2 0.1 0.3 1.4 0.1 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 358.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV8-61 ENSG00000211638 "Immunoglobulin lambda variable 8-61" A0A075B6I0 22 22098700-22099212 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 805.8;lymphoid tissue: 984.2" "Cell type enriched" "Detected in some" 4 "B-cells: 25.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.5" "Group enriched" "Detected in some" 630 "memory B-cell: 257.8;naive B-cell: 529.3" "Lineage enriched" "Detected in single" 848 "B-cells: 529.3" "Cell line enhanced" "Detected in some" "Daudi: 2.2;RPMI-8226: 3.6;SH-SY5Y: 1.8;U-266/70: 6.6" "Low region specificity" "Detected in all" "Immunoglobulin genes" NA NA 620000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.07e-3)" "unprognostic (2.73e-2)" "prognostic favorable (3.84e-4)" "unprognostic (1.07e-2)" "unprognostic (5.24e-2)" "unprognostic (1.04e-3)" "unprognostic (1.65e-1)" "unprognostic (1.75e-3)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (3.32e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (8.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-1)" 9.4 4.9 0.1 125.5 0.2 63.9 78.3 0.1 3.5 43.5 1.0 201.1 805.8 22.7 0.8 10.6 5.6 46.4 11.7 0.1 0.2 5.3 13.7 82.2 257.2 0.2 0.1 9.2 13.4 1.3 0.8 0.0 0.7 10.5 191.0 0.0 108.6 1.0 0.2 4.0 161.6 13.0 0.8 275.7 179.2 3.3 0.1 16.5 11.5 0.0 984.2 247.8 3.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.4 0.0 0.0 0.0 0.2 3.6 0.0 0.0 1.0 1.8 0.2 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.3 6.6 1.0 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.2 0.2 0.1 257.8 0.3 0.0 0.4 529.3 0.0 0.0 0.2 0.1 0.4 0.1 0.2 32.7 0.1 0.2 0.1 3.5 0.1 0.2 0.2 0.1 0.7 0.8 0.1 1.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 1.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV4-60 ENSG00000211639 "Immunoglobulin lambda variable 4-60" A0A075B6I1 22 22162199-22162681 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 193.1;lymphoid tissue: 116.3;urinary bladder: 185.2" "Cell type enriched" "Detected in some" 152 "Plasma cells: 1125.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 78 "memory B-cell: 79.4;naive B-cell: 48.9" "Lineage enriched" "Detected in single" 96 "B-cells: 79.4" "Group enriched" "Detected in some" 4 "Daudi: 7.8;HEL: 13.3;U-698: 3.9" "Immunoglobulin genes" NA NA 120000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.57e-4)" "unprognostic (5.46e-3)" "unprognostic (9.43e-3)" "unprognostic (1.26e-2)" "prognostic favorable (1.89e-4)" "unprognostic (3.06e-2)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.81e-1)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (1.78e-1)" "unprognostic (1.08e-1)" "unprognostic (4.19e-1)" "unprognostic (2.60e-1)" 1.8 1.9 0.0 32.9 0.0 18.1 36.6 0.0 0.2 3.3 0.1 70.7 193.1 1.5 0.0 12.3 1.9 3.4 11.4 0.0 0.0 3.1 3.9 43.5 116.3 0.0 0.0 4.6 1.1 0.4 0.2 0.2 0.1 1.1 73.3 0.0 37.9 0.8 0.1 0.1 86.8 2.1 0.0 80.3 37.7 1.7 0.0 18.3 1.7 0.0 112.0 185.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 3.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.4 0.1 0.0 0.0 48.9 0.0 0.0 0.8 0.0 0.0 0.0 0.4 3.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1125.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV6-57 ENSG00000211640 "Immunoglobulin lambda variable 6-57" P01721 22 22195799-22196276 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1814.6;urinary bladder: 675.2" "Cell type enriched" "Detected in some" 72 "Plasma cells: 10791.0" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "memory B-cell: 353.9;naive B-cell: 292.4" "Lineage enriched" "Detected in many" 13 "B-cells: 353.9" "Cell line enhanced" "Detected in some" "Daudi: 148.0;RPMI-8226: 40.6;U-266/70: 21.6;U-698: 47.3" "Immunoglobulin genes" NA NA 1900000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.92e-6)" "unprognostic (5.73e-2)" "unprognostic (2.59e-2)" "unprognostic (2.11e-2)" "unprognostic (1.14e-2)" "prognostic favorable (1.36e-5)" "unprognostic (1.87e-2)" "unprognostic (2.56e-1)" "unprognostic (6.55e-2)" "unprognostic (3.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (2.30e-6)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" 15.6 9.1 0.0 220.8 0.1 191.7 215.5 0.0 0.6 82.3 0.4 485.0 351.3 19.1 4.4 171.4 38.2 75.8 39.2 0.1 0.0 10.7 26.8 97.0 237.6 0.6 0.1 20.3 7.7 17.8 1.1 0.4 0.5 17.2 318.8 0.0 249.6 12.7 0.3 3.2 174.3 11.5 0.1 276.6 437.6 15.9 0.1 139.7 15.3 0.0 1814.6 675.2 8.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 148.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.2 1.0 40.6 0.0 0.0 2.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.2 0.4 21.6 15.2 47.3 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 2.3 353.9 0.1 0.1 0.2 292.4 0.1 0.1 27.9 0.1 0.1 1.2 0.2 27.6 0.0 0.1 0.0 0.6 0.1 0.0 0.6 0.1 0.5 0.1 0.1 0.3 0.0 0.0 0.6 0.0 148.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 1.8 26.7 0.0 0.0 0.0 4.4 67.8 0.0 0.0 0.0 3.6 2.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10791.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.0 6.2 0.0 0.5 0.0 IGLV11-55 ENSG00000211641 "Immunoglobulin lambda variable 11-55 (non-functional)" A0A075B6I3 22 22201663-22202161 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.1" "Cell type enhanced" "Detected in some" "Late spermatids: 3.5;Plasma cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Daudi: 8.6;U-698: 2.7" "Immunoglobulin genes" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.22e-1)" "unprognostic (6.16e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.5 0.2 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 VPREB1 "CD179A, VpreB" ENSG00000169575 "V-set pre-B cell surrogate light chain 1" P12018 22 22244780-22245515 "CD markers, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "bone marrow: 29.8" "Cell type enhanced" "Detected in single" "NK-cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 5.7;naive B-cell: 5.3" "Lineage enriched" "Detected in many" 4 "B-cells: 5.7" "Group enriched" "Detected in some" 11 "Daudi: 9.4;MOLT-4: 19.8;RPMI-8226: 5.4" "Not detected" "Not detected" HPA055886 Approved "Intracellular and membrane" NA NA 62000 "Cluster 37: B-cells - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 33: Fibroblasts - ECM organization" "HPA055886: AB_2682956" 0.0 0.0 0.0 0.0 0.0 29.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 IGLV5-52 ENSG00000211643 "Immunoglobulin lambda variable 5-52" A0A0A0MRZ9 22 22318727-22319226 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in single" 5 "B-cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory B-cell: 11.7;naive B-cell: 10.3" "Lineage enriched" "Detected in many" 6 "B-cells: 11.7" "Low cell line specificity" "Detected in all" "Immunoglobulin genes" NA NA 1200000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "unprognostic (7.26e-2)" "unprognostic (7.05e-2)" "unprognostic (1.86e-2)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (7.61e-5)" "unprognostic (1.22e-1)" "unprognostic (1.89e-1)" "unprognostic (8.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.93e-2)" "unprognostic (2.25e-3)" "unprognostic (7.75e-2)" "unprognostic (3.51e-2)" "unprognostic (1.57e-1)" "unprognostic (5.46e-2)" 11.5 10.4 10.7 18.0 11.7 14.6 23.8 16.4 14.1 16.5 13.2 26.6 20.1 28.4 44.2 22.5 22.7 22.5 16.6 11.9 11.1 11.5 9.5 14.9 44.1 9.4 9.4 21.6 8.0 13.9 8.6 11.2 11.0 15.9 23.5 22.5 17.9 15.0 10.1 37.7 15.3 22.3 9.2 21.8 29.2 12.9 10.8 17.7 21.4 15.6 53.5 31.1 6.3 13.9 12.1 7.7 18.8 29.2 22.3 25.1 14.4 7.7 19.0 17.3 22.0 15.6 5.0 38.4 8.5 22.5 10.1 16.9 36.0 25.6 24.0 9.4 27.3 13.4 21.4 14.8 8.7 20.8 22.9 24.0 24.0 19.5 34.5 14.2 35.2 13.9 40.7 3.3 32.3 14.5 7.0 13.9 10.5 22.5 5.7 9.4 9.4 6.4 22.6 16.1 21.2 13.2 9.9 10.6 10.9 15.7 21.0 4.8 21.0 40.9 25.7 4.2 9.0 6.7 21.9 18.2 14.0 15.4 12.2 0.0 1.3 1.9 1.1 0.7 1.3 11.7 1.2 1.3 1.5 10.3 0.8 0.8 0.7 0.7 0.8 1.4 0.6 3.1 10.7 11.7 16.4 14.1 11.9 11.1 9.4 9.4 11.0 9.2 10.8 13.9 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 IGLV1-51 ENSG00000211644 "Immunoglobulin lambda variable 1-51" P01701 22 22322472-22322969 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1318.8;lymphoid tissue: 3027.3;urinary bladder: 1584.8" "Cell type enriched" "Detected in some" 312 "Plasma cells: 34336.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "memory B-cell: 275.9;naive B-cell: 178.3" "Lineage enriched" "Detected in many" 10 "B-cells: 275.9" "Cell line enhanced" "Detected in many" "HEK 293: 17.9" "Immunoglobulin genes" NA NA 1700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.85e-4)" "unprognostic (1.71e-2)" "unprognostic (3.12e-3)" "unprognostic (1.76e-3)" "unprognostic (1.61e-1)" "prognostic favorable (1.95e-5)" "unprognostic (3.55e-3)" "unprognostic (3.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.40e-5)" "unprognostic (1.21e-1)" "unprognostic (5.70e-2)" "unprognostic (1.89e-1)" "unprognostic (1.07e-1)" 43.5 318.8 1.1 484.8 1.9 274.1 627.0 4.6 7.1 73.2 2.0 1318.8 1139.1 38.0 16.9 287.4 52.8 238.0 70.2 1.4 1.6 32.7 53.3 179.1 343.1 4.0 1.4 185.0 39.0 5.8 4.1 1.5 4.2 34.4 930.0 3.1 695.2 49.5 1.9 13.1 702.1 49.8 1.9 934.5 956.7 11.7 1.5 274.0 63.0 1.7 3027.3 1584.8 17.7 2.7 1.3 0.6 1.6 3.8 3.5 1.7 5.9 1.4 3.2 3.1 2.0 2.3 1.0 8.8 1.6 0.8 1.1 3.1 1.9 3.8 2.2 1.4 17.9 3.9 4.5 2.4 0.7 3.4 1.7 5.2 1.0 2.7 0.3 0.4 3.1 0.9 3.9 0.9 3.0 1.6 2.6 3.8 3.0 2.8 4.1 2.3 2.7 8.8 3.6 1.4 8.3 4.9 2.0 1.4 1.8 0.9 2.7 0.3 4.3 4.4 9.2 1.0 1.2 2.0 2.0 2.0 0.4 2.8 0.8 0.1 0.5 0.0 0.2 0.2 26.3 275.9 0.2 0.3 0.1 178.3 0.7 0.5 0.4 0.1 0.3 0.2 0.2 26.4 1.1 1.9 4.6 7.1 1.4 1.6 4.0 1.4 4.2 1.9 1.5 2.7 0.0 0.0 0.5 0.0 109.8 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 4.8 35.7 0.1 0.0 0.0 0.7 1.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 34336.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 19.3 0.0 0.0 9.4 0.0 0.0 0.0 IGLV1-50 ENSG00000211645 "Immunoglobulin lambda variable 1-50 (non-functional)" A0A075B6I6 22 22327300-22327814 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 16.4;lymphoid tissue: 14.7;stomach 1: 20.4" "Cell type enriched" "Detected in single" 2575 "Plasma cells: 1545.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 21 "memory B-cell: 11.0;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 33 "B-cells: 11.0" "Cell line enhanced" "Detected in single" "HEK 293: 1.1" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-4)" "unprognostic (8.01e-2)" "unprognostic (1.28e-3)" "unprognostic (6.91e-2)" "unprognostic (2.10e-1)" "prognostic favorable (7.08e-4)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (7.38e-2)" "unprognostic (1.58e-4)" "unprognostic (4.89e-3)" "unprognostic (1.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.59e-2)" 0.5 0.5 0.1 6.1 0.1 3.3 6.7 1.7 1.9 0.5 0.0 5.4 16.4 0.6 1.2 2.4 0.5 0.8 0.0 0.6 0.0 0.2 0.2 4.4 1.9 0.6 0.0 0.9 0.1 0.1 0.1 0.0 0.6 0.3 4.5 0.7 4.6 0.3 0.4 0.0 9.4 0.2 0.0 3.9 20.4 0.4 0.0 0.6 0.2 0.0 14.7 9.3 0.1 1.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.3 0.5 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.1 0.0 0.3 0.1 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 11.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.7 1.9 0.6 0.0 0.6 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1545.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV9-49 ENSG00000223350 "Immunoglobulin lambda variable 9-49" A0A0B4J1Y8 22 22343187-22343732 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 125.5;lymphoid tissue: 118.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 46.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 672 "memory B-cell: 70.3;naive B-cell: 88.1" "Lineage enriched" "Detected in single" 747 "B-cells: 88.1" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 43000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.04e-5)" "unprognostic (4.30e-3)" "unprognostic (1.83e-2)" "unprognostic (5.61e-2)" "prognostic favorable (2.00e-5)" "unprognostic (6.29e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (2.13e-1)" "prognostic unfavorable (1.12e-8)" "unprognostic (1.66e-1)" "unprognostic (3.07e-1)" "unprognostic (3.90e-2)" "unprognostic (7.16e-2)" 2.4 125.5 0.0 14.7 0.0 9.8 6.1 0.1 0.5 3.3 0.0 33.6 36.5 2.2 0.0 6.0 3.2 1.1 1.2 0.2 0.0 1.2 4.4 43.8 118.0 0.2 0.0 3.3 1.4 0.0 0.1 0.1 0.2 0.9 15.1 0.0 29.7 1.0 0.1 0.1 28.2 0.4 0.0 65.9 46.3 2.0 0.0 14.0 3.4 0.1 97.9 39.2 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.3 0.0 0.0 0.1 88.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV5-48 ENSG00000211647 "Immunoglobulin lambda variable 5-48 (non-functional)" A0A075B6I7 22 22352940-22353433 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 5.5;urinary bladder: 2.7" "Cell type enriched" "Detected in some" 8 "Plasma cells: 19.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 61 "memory B-cell: 5.4;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 68 "B-cells: 6.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.76e-3)" "unprognostic (1.91e-2)" "unprognostic (9.43e-2)" "unprognostic (3.36e-4)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (1.74e-2)" "unprognostic (2.97e-1)" 0.0 0.0 0.0 0.9 0.0 1.3 0.9 0.0 0.6 0.4 0.0 3.3 3.3 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.1 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 1.3 0.2 0.0 5.5 0.7 0.0 0.0 2.5 0.1 0.0 5.3 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-47 ENSG00000211648 "Immunoglobulin lambda variable 1-47" P01700 22 22357739-22358260 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 706.6;lymphoid tissue: 1804.0;stomach 1: 625.5" "Cell type enriched" "Detected in some" 114 "Plasma cells: 10777.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 638 "memory B-cell: 1518.1;naive B-cell: 819.6" "Lineage enriched" "Detected in many" 828 "B-cells: 1518.1" "Cell line enhanced" "Detected in some" "HL-60: 2.1;RH-30: 2.1;RPMI-8226: 4.2;SCLC-21H: 2.7;SH-SY5Y: 2.4;U-698: 7.1" "Immunoglobulin genes" NA NA 3000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (5.19e-3)" "unprognostic (2.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (1.26e-1)" "prognostic favorable (2.66e-4)" "unprognostic (4.44e-2)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.28e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (5.12e-8)" "unprognostic (5.00e-3)" "unprognostic (1.62e-1)" "unprognostic (7.08e-2)" "unprognostic (1.15e-2)" 36.0 216.0 0.6 323.0 0.4 162.3 200.5 0.4 2.3 82.1 0.7 706.6 704.7 23.8 3.0 163.7 21.3 112.7 27.2 0.2 0.5 23.2 31.8 126.7 689.2 2.6 0.4 43.5 8.9 4.9 2.1 0.5 1.2 22.5 531.5 0.2 526.6 70.2 0.7 4.7 332.8 34.7 0.5 813.7 625.5 9.8 0.4 260.1 34.1 0.0 1804.0 367.0 10.3 2.4 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.7 2.1 4.2 0.0 0.0 2.7 2.4 0.5 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.0 0.1 0.6 0.0 7.1 0.0 0.9 0.0 0.7 1.2 0.5 0.7 0.1 0.5 1518.1 0.7 0.6 1.0 819.6 0.3 0.6 0.6 0.5 0.5 1.8 0.6 159.6 0.6 0.4 0.4 2.3 0.2 0.5 2.6 0.4 1.2 0.5 0.4 2.4 0.0 0.0 0.0 0.0 94.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.7 0.0 0.0 0.0 1.7 29.0 0.0 0.0 0.0 0.7 1.7 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10777.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.3 0.0 IGLV7-46 ENSG00000211649 "Immunoglobulin lambda variable 7-46" A0A075B6I9 22 22369614-22370087 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 400.6;lymphoid tissue: 459.1;stomach 1: 250.7;urinary bladder: 444.0" "Cell type enriched" "Detected in some" 180 "Plasma cells: 6758.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Group enriched" "Detected in some" 377 "memory B-cell: 183.6;naive B-cell: 82.3" "Lineage enriched" "Detected in single" 521 "B-cells: 183.6" "Cell line enhanced" "Detected in some" "Daudi: 8.0;RPMI-8226: 2.8;U-698: 6.6" HPA003182 Approved "Immunoglobulin genes" NA NA 270000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (3.34e-6)" "unprognostic (1.21e-1)" "unprognostic (1.10e-2)" "unprognostic (3.94e-3)" "unprognostic (4.25e-3)" "unprognostic (4.68e-3)" "unprognostic (1.74e-1)" "unprognostic (2.77e-2)" "unprognostic (7.47e-3)" "unprognostic (2.17e-1)" "unprognostic (4.02e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (2.02e-1)" 15.1 3.8 0.0 59.8 0.3 44.2 171.7 0.1 0.9 4.1 0.1 400.6 162.4 4.4 0.0 43.7 3.0 56.0 5.2 0.0 1.6 5.7 7.7 44.9 82.2 0.4 0.0 9.0 6.2 0.1 0.8 0.1 0.2 2.5 298.6 0.0 107.2 5.2 0.5 0.8 133.1 12.1 0.1 248.1 250.7 0.7 0.2 57.3 8.7 0.0 459.1 444.0 3.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.3 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.3 0.0 6.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 183.6 0.1 0.0 0.1 82.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 15.2 0.0 0.3 0.1 0.9 0.0 1.6 0.4 0.0 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 12.8 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6758.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 IGLV5-45 ENSG00000211650 "Immunoglobulin lambda variable 5-45" A0A087WSX0 22 22375986-22376505 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 40.5;intestine: 43.5;lymphoid tissue: 97.5;salivary gland: 49.0" "Cell type enriched" "Detected in some" 116 "Plasma cells: 6697.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "memory B-cell: 1.2;naive B-cell: 1.1" "Lineage enriched" "Detected in single" 11 "B-cells: 1.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 160000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (4.62e-4)" "unprognostic (6.18e-2)" "unprognostic (2.26e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "prognostic favorable (2.70e-5)" "unprognostic (1.58e-3)" "unprognostic (2.77e-1)" "unprognostic (8.89e-2)" "unprognostic (1.06e-1)" "unprognostic (5.16e-2)" "unprognostic (3.08e-1)" "prognostic unfavorable (5.95e-6)" "unprognostic (6.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-1)" "unprognostic (8.36e-2)" 2.2 0.3 0.0 0.0 0.0 0.4 5.5 0.0 0.4 3.3 0.0 43.5 0.0 0.7 0.0 40.5 2.0 0.0 0.2 0.0 0.0 2.5 3.1 9.6 0.0 0.1 0.0 0.6 0.6 0.0 0.2 0.0 0.1 1.1 0.2 0.0 49.0 0.0 0.1 0.7 42.1 0.0 0.0 97.5 14.1 0.4 0.0 0.0 4.0 0.0 1.4 14.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 57.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6697.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 IGLV1-44 ENSG00000211651 "Immunoglobulin lambda variable 1-44" P01699 22 22380766-22381347 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 589.7;lymphoid tissue: 1918.7;stomach 1: 534.3" "Cell type enriched" "Detected in some" 108 "Plasma cells: 12023.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 840 "memory B-cell: 968.8;naive B-cell: 850.4" "Lineage enriched" "Detected in many" 894 "B-cells: 968.8" "Cell line enhanced" "Detected in some" "Daudi: 21.3;RPMI-8226: 5.5;SCLC-21H: 4.1;U-698: 15.2" "Immunoglobulin genes" NA NA 4000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.88e-3)" "unprognostic (1.51e-2)" "unprognostic (2.40e-2)" "unprognostic (7.23e-3)" "unprognostic (4.81e-3)" "prognostic favorable (4.71e-5)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-2)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.55e-8)" "unprognostic (1.85e-1)" "unprognostic (1.98e-1)" "unprognostic (6.48e-2)" "unprognostic (5.49e-2)" 33.9 2.0 0.1 297.2 0.0 133.4 110.2 0.0 0.8 14.3 0.0 378.7 589.7 11.8 0.0 80.1 19.5 78.7 17.5 0.0 0.0 18.7 17.1 122.2 519.5 1.3 0.2 15.3 3.6 0.0 2.6 0.0 0.4 13.8 263.1 0.0 273.0 9.4 0.7 2.4 236.5 21.4 0.0 608.7 534.3 11.6 0.1 117.8 35.1 0.0 1918.7 240.5 16.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 5.5 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 968.8 0.0 0.0 0.7 850.4 0.0 0.0 0.0 0.0 0.1 1.0 0.1 100.0 0.1 0.0 0.0 0.8 0.0 0.0 1.3 0.2 0.4 0.0 0.1 0.8 0.0 0.0 0.6 0.0 111.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 2.7 0.0 0.0 0.0 3.5 48.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12023.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.3 0.0 IGLV7-43 ENSG00000211652 "Immunoglobulin lambda variable 7-43" P04211 22 22395018-22395489 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 161.9;lymphoid tissue: 238.7;stomach 1: 115.9" "Cell type enriched" "Detected in some" 57 "Plasma cells: 1304.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 325 "memory B-cell: 132.0;naive B-cell: 54.2" "Lineage enriched" "Detected in single" 461 "B-cells: 132.0" "Cell line enhanced" "Detected in some" "Daudi: 1.9;RPMI-8226: 1.4;U-698: 1.5" HPA003182 Approved "Immunoglobulin genes" NA NA 130000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003182: " "prognostic favorable (6.49e-6)" "unprognostic (7.85e-3)" "prognostic favorable (7.00e-4)" "unprognostic (5.57e-2)" "unprognostic (3.62e-2)" "prognostic favorable (3.08e-5)" "unprognostic (7.63e-3)" "unprognostic (8.20e-2)" "unprognostic (2.42e-1)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (6.29e-2)" "unprognostic (8.34e-2)" "unprognostic (1.68e-1)" "unprognostic (2.29e-1)" 8.0 0.8 0.0 31.2 0.1 15.8 45.7 0.0 0.5 4.9 0.0 161.9 132.8 3.6 0.5 7.9 3.3 22.1 3.5 0.0 0.1 3.1 4.2 13.0 59.0 0.0 0.0 4.1 2.2 0.0 1.0 0.2 0.1 2.3 129.3 0.0 72.5 4.7 0.1 0.5 57.1 17.7 0.0 168.6 115.9 0.5 0.0 31.3 6.4 0.7 238.7 31.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 132.0 0.0 0.0 0.0 54.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.2 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1304.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.2 0.0 IGLV1-40 ENSG00000211653 "Immunoglobulin lambda variable 1-40" P01703 22 22409766-22410282 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1291.5;stomach 1: 1287.4" "Cell type enriched" "Detected in some" 358 "Plasma cells: 43406.7" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in some" "cerebral cortex: 3.0" "Group enriched" "Detected in some" 496 "memory B-cell: 666.4;naive B-cell: 576.7" "Lineage enriched" "Detected in many" 532 "B-cells: 666.4" "Cell line enhanced" "Detected in some" "Daudi: 3.5;RPMI-8226: 2.2;SH-SY5Y: 3.4;TIME: 2.3" "Immunoglobulin genes" NA NA 2300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.64e-3)" "unprognostic (4.68e-3)" "unprognostic (3.88e-2)" "unprognostic (3.37e-3)" "unprognostic (9.60e-3)" "prognostic favorable (5.74e-6)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (8.43e-2)" "unprognostic (5.51e-2)" "unprognostic (1.06e-1)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.44e-6)" "unprognostic (1.51e-1)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" 43.4 13.0 0.8 203.5 0.5 114.3 138.5 0.1 3.0 68.1 1.1 553.8 551.6 14.8 0.6 125.4 21.5 236.0 15.2 0.2 0.2 28.8 28.3 115.4 282.5 0.3 0.2 56.6 10.0 1.1 3.4 0.6 0.6 46.1 336.7 4.2 413.8 19.7 1.2 3.1 287.2 14.3 0.2 1029.8 1287.4 7.2 0.3 179.2 61.2 0.0 1291.5 464.8 19.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.3 1.0 1.1 0.0 0.0 0.2 0.8 2.2 0.0 0.0 1.3 3.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.4 0.7 0.7 1.1 1.1 0.8 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.6 666.4 0.3 0.3 0.6 576.7 0.1 0.2 1.2 0.3 0.3 0.6 0.4 53.7 0.8 0.5 0.1 3.0 0.2 0.2 0.3 0.2 0.6 0.2 0.3 1.0 0.0 0.0 0.0 0.0 121.0 0.0 0.0 0.0 2.2 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 1.2 8.0 0.0 0.0 0.0 28.6 64.2 0.0 0.0 0.0 1.8 0.9 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.7 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 43406.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 7.4 0.0 0.1 0.0 IGLV5-37 ENSG00000211654 "Immunoglobulin lambda variable 5-37" A0A075B6J1 22 22427540-22428035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "gallbladder: 24.7;intestine: 10.5;lymphoid tissue: 41.5;salivary gland: 11.5;stomach 1: 16.5" "Group enriched" "Detected in some" 4 "B-cells: 2.5;Late spermatids: 1.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 54 "memory B-cell: 6.1;naive B-cell: 7.0" "Lineage enriched" "Detected in single" 58 "B-cells: 7.0" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 14000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (4.69e-4)" "unprognostic (2.44e-2)" "unprognostic (5.68e-3)" "unprognostic (4.26e-1)" "prognostic favorable (4.71e-4)" "unprognostic (4.97e-2)" "unprognostic (3.56e-2)" "unprognostic (3.15e-1)" "unprognostic (5.34e-6)" "unprognostic (1.66e-1)" "unprognostic (4.32e-1)" "unprognostic (1.25e-1)" 0.7 0.0 0.0 9.5 0.0 1.0 3.2 0.0 0.0 1.8 0.0 10.5 10.1 0.2 0.0 4.2 0.9 24.7 1.1 0.0 0.0 0.9 0.7 3.6 4.5 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.6 8.0 0.1 11.5 0.0 0.0 0.0 8.8 0.2 0.0 22.7 16.5 1.2 0.0 8.4 0.6 0.0 41.5 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV1-36 ENSG00000211655 "Immunoglobulin lambda variable 1-36" A0A0B4J1U3 22 22431958-22432465 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 268.7;stomach 1: 122.4;urinary bladder: 86.4" "Cell type enriched" "Detected in some" 13 "Plasma cells: 59.2" "Cancer enhanced" "Detected in many" "lung cancer: 33.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 625 "memory B-cell: 60.9;naive B-cell: 85.8" "Lineage enriched" "Detected in single" 731 "B-cells: 85.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 980000000 "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (1.55e-4)" "unprognostic (5.15e-2)" "unprognostic (2.04e-2)" "prognostic favorable (2.60e-4)" "unprognostic (1.11e-3)" "unprognostic (1.15e-2)" "unprognostic (1.50e-1)" "unprognostic (6.51e-2)" "unprognostic (2.12e-1)" "unprognostic (4.53e-2)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.64e-5)" "unprognostic (2.99e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.07e-1)" 1.8 0.3 0.0 19.6 0.0 14.4 23.7 0.0 0.1 6.0 0.0 28.2 21.6 0.7 0.6 10.5 9.1 7.3 6.0 0.0 0.0 3.3 3.3 8.7 16.6 0.0 0.0 1.7 1.1 0.0 0.1 0.0 0.0 1.6 44.7 0.0 37.3 3.0 0.0 0.6 12.3 0.8 0.0 108.1 122.4 0.3 0.0 30.5 2.8 0.0 268.7 86.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 60.9 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 59.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ZNF280B "5'OY11.1, SUHW2, ZNF279, ZNF632" ENSG00000275004 "Zinc finger protein 280B" Q86YH2 22 22484421-22508742 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.4" "Group enriched" "Detected in many" 7 "Early spermatids: 135.6;Late spermatids: 99.3;Spermatocytes: 104.2;Spermatogonia: 161.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 20.9;U-2 OS: 9.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059519 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA059519: AB_2684050" "unprognostic (7.32e-2)" "unprognostic (2.99e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (2.65e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-1)" "unprognostic (1.14e-2)" "unprognostic (2.85e-3)" "unprognostic (1.10e-1)" "unprognostic (5.42e-2)" "unprognostic (3.34e-2)" "unprognostic (4.80e-1)" "unprognostic (2.44e-2)" "unprognostic (5.34e-2)" 0.1 1.6 2.4 0.6 2.4 0.3 0.2 1.5 3.2 0.4 0.1 0.3 0.2 1.1 1.0 0.2 0.8 0.4 0.5 2.3 4.0 0.2 0.1 0.2 1.0 2.3 2.8 2.1 0.6 1.2 1.3 0.2 2.3 0.9 0.4 3.3 0.2 1.0 0.3 0.3 0.4 0.8 1.6 0.9 0.4 13.4 3.6 0.8 1.9 0.2 0.9 0.2 0.1 2.2 0.0 2.5 3.2 0.0 0.0 0.0 3.7 0.5 0.0 0.0 0.0 1.8 1.1 3.2 3.1 0.1 3.0 0.0 2.8 0.3 0.0 0.0 3.8 4.0 0.6 3.6 2.4 2.5 4.4 1.2 0.0 2.7 0.0 0.5 2.7 3.1 20.9 1.4 1.0 0.0 3.0 1.7 2.4 1.5 0.5 3.0 0.0 0.2 0.8 0.0 2.0 2.2 0.0 0.0 1.1 2.6 0.0 1.9 1.0 4.4 9.8 1.0 0.1 1.7 1.9 1.9 3.0 2.1 0.2 12.9 1.6 2.9 2.6 2.5 4.2 2.8 3.2 2.5 1.5 2.8 3.8 4.5 4.1 5.2 5.4 2.4 2.6 1.8 2.4 2.4 1.5 3.2 2.3 4.0 2.3 2.8 2.3 1.6 3.6 2.2 0.1 0.0 0.6 3.9 5.3 0.1 0.6 0.4 0.0 7.1 0.9 1.3 2.6 2.8 0.6 0.0 4.2 0.3 0.8 0.3 0.0 2.8 135.6 3.4 2.4 1.8 3.0 0.4 12.7 3.7 0.3 1.3 1.1 3.9 0.0 11.4 1.4 0.2 3.0 5.0 14.6 0.7 0.0 0.8 1.9 99.3 2.5 2.6 5.4 1.0 1.9 6.9 5.2 7.5 4.2 2.3 0.1 7.2 0.7 0.8 0.0 4.4 0.0 8.0 6.6 2.3 0.5 104.2 161.7 0.0 0.0 0.3 2.3 17.2 1.6 0.1 ZNF280A "3'OY11.1, SUHW1, ZNF280, ZNF636" ENSG00000169548 "Zinc finger protein 280A" P59817 22 22513736-22520270 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "adrenal gland: 1.4" "Cell type enhanced" "Detected in some" "Melanocytes: 1.8;Spermatogonia: 1.2;Syncytiotrophoblasts: 5.1;Theca cells: 1.9" "Cancer enhanced" "Detected in some" "melanoma: 1.7;testis cancer: 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.8;K-562: 8.2;SK-MEL-30: 2.1" HPA044475 Approved Nucleoplasm NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "HPA044475: AB_10960420" "unprognostic (7.53e-2)" "unprognostic (3.76e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-2)" "unprognostic (3.29e-1)" "unprognostic (4.65e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.3 0.2 0.3 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.0 0.0 5.1 0.0 1.9 0.0 0.0 PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 105.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 249.0" "Cancer enhanced" "Detected in many" "melanoma: 139.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "K-562: 834.1" "Not detected" "Not detected" "HPA045153, HPA068562" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA045153: AB_10797259, HPA068562: " "unprognostic (9.36e-3)" "unprognostic (9.74e-2)" "unprognostic (1.02e-1)" "unprognostic (3.87e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.41e-4)" "unprognostic (3.43e-2)" "unprognostic (4.00e-2)" "unprognostic (1.33e-1)" "unprognostic (6.52e-3)" "unprognostic (9.68e-3)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.48e-9)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (8.87e-2)" "unprognostic (1.26e-1)" 0.2 3.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.2 0.0 3.4 10.0 0.0 0.5 0.0 0.3 0.0 0.1 1.8 0.1 0.2 0.1 0.1 0.0 4.7 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.1 105.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.2 0.9 53.3 0.0 126.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.4 0.7 3.5 88.8 0.0 0.5 0.1 4.3 0.0 0.0 61.5 14.8 36.0 21.7 0.6 0.0 2.9 172.6 0.0 0.0 0.0 0.0 0.0 0.0 14.9 834.1 15.6 0.0 8.1 0.3 0.2 0.0 27.2 3.5 5.0 0.0 0.2 0.0 0.2 1.1 185.0 0.0 0.6 0.2 0.0 27.8 24.3 5.0 0.1 159.6 0.0 0.2 3.0 14.6 1.3 0.2 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 37.8 22.3 1.1 0.3 0.0 0.0 0.0 0.0 0.9 2.0 0.0 13.0 0.0 60.9 0.0 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 41.4 5.6 0.4 0.0 0.0 3.1 0.2 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.8 0.0 0.4 6.6 0.0 2.7 41.8 249.0 0.0 0.0 0.0 0.1 14.2 0.1 0.0 IGLV2-33 ENSG00000211656 "Immunoglobulin lambda variable 2-33 (non-functional)" A0A075B6J2 22 22588155-22588688 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.3;lymphoid tissue: 2.7;salivary gland: 2.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 2.9;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 30 "B-cells: 2.9" "Group enriched" "Detected in some" 9 "RPMI-8226: 1.5;U-266/70: 5.1;U-266/84: 3.4" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "unprognostic (1.29e-2)" "unprognostic (1.79e-3)" "unprognostic (2.13e-1)" "unprognostic (4.30e-1)" "unprognostic (2.64e-3)" "unprognostic (2.47e-2)" "unprognostic (2.06e-1)" "unprognostic (6.68e-2)" 0.0 0.1 0.0 1.5 0.0 1.3 0.4 0.0 0.0 0.0 0.0 2.2 4.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 2.6 0.0 0.0 0.0 2.3 0.2 0.0 1.5 1.5 0.0 0.0 0.1 0.0 0.0 2.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-32 ENSG00000211657 "Immunoglobulin lambda variable 3-32 (non-functional)" A0A0A0MS00 22 22594528-22595056 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "urinary bladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immunoglobulin genes" NA NA "Cluster 14: B-cells - Humoral immune response" "unprognostic (4.68e-2)" "unprognostic (1.31e-1)" "unprognostic (7.93e-2)" 0.0 0.0 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GGTLC2 GGTL4 ENSG00000100121 "Gamma-glutamyltransferase light chain 2" Q14390 22 22644475-22647903 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 19 "testis: 18.0" "Group enriched" "Detected in some" 14 "Alveolar cells type 1: 22.4;Early spermatids: 24.6;Late spermatids: 28.4;Spermatocytes: 14.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 1.6;U-2 OS: 3.3" "HPA045635, HPA047534" Uncertain NA NA "Cluster 15: NK-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA045635: AB_2679400, HPA047534: AB_2680079" "unprognostic (2.58e-2)" "unprognostic (2.35e-2)" "unprognostic (7.17e-2)" "unprognostic (2.96e-1)" "unprognostic (4.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.06e-3)" "unprognostic (1.48e-2)" "unprognostic (1.55e-1)" 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.5 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 18.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.0 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 22.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-27 ENSG00000211658 "Immunoglobulin lambda variable 3-27" P01718 22 22668288-22668806 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lymphoid tissue: 401.6" "Cell type enriched" "Detected in some" 135 "Plasma cells: 1406.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 719 "memory B-cell: 194.0;naive B-cell: 367.8" "Lineage enriched" "Detected in single" 941 "B-cells: 367.8" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 720000000 "Cluster 24: B-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (3.45e-2)" "unprognostic (1.87e-3)" "unprognostic (5.44e-2)" "unprognostic (4.30e-3)" "prognostic favorable (3.60e-7)" "unprognostic (8.55e-2)" "unprognostic (2.16e-1)" "unprognostic (5.91e-2)" "unprognostic (9.56e-2)" "unprognostic (4.55e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.95e-9)" "unprognostic (1.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.90e-1)" "unprognostic (2.07e-1)" 8.8 1.8 0.1 16.4 0.0 29.4 29.7 0.0 0.5 23.7 0.1 56.7 19.3 2.2 0.0 10.3 5.1 10.5 3.1 0.0 0.0 3.7 3.7 29.3 64.3 0.4 0.0 2.9 0.3 0.2 0.4 0.0 0.1 2.4 26.9 0.0 40.6 0.8 0.0 0.5 24.4 0.6 0.0 103.9 59.8 24.2 0.0 47.6 2.8 0.0 401.6 27.4 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.1 194.0 0.2 0.0 0.3 367.8 0.0 0.0 0.2 0.0 0.1 0.1 0.1 11.8 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1406.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 IGLV3-25 ENSG00000211659 "Immunoglobulin lambda variable 3-25" P01717 22 22686726-22687271 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2440.7;stomach 1: 1015.7" "Cell type enriched" "Detected in some" 41 "Plasma cells: 17441.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 45 "memory B-cell: 545.0;naive B-cell: 794.2" "Lineage enriched" "Detected in many" 53 "B-cells: 794.2" "Cell line enhanced" "Detected in some" "HL-60: 2.6;RPMI-8226: 2.7;SCLC-21H: 4.6;SH-SY5Y: 5.1" HPA003285 Approved "Immunoglobulin genes" NA NA 3200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (5.55e-4)" "unprognostic (8.28e-2)" "unprognostic (4.28e-3)" "unprognostic (2.89e-2)" "unprognostic (2.88e-2)" "prognostic favorable (1.43e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (1.87e-1)" "unprognostic (1.98e-2)" "unprognostic (4.86e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (3.78e-7)" "unprognostic (1.25e-1)" "unprognostic (4.78e-1)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" 56.8 163.2 0.2 293.2 0.2 243.2 430.9 0.1 1.7 151.9 1.3 847.4 338.9 20.8 2.1 161.5 49.8 177.1 29.8 0.2 0.3 17.1 45.7 870.5 1024.7 1.8 0.2 21.8 14.5 1.7 1.7 0.5 0.6 18.9 467.5 0.0 532.3 116.5 0.7 2.4 228.9 34.1 0.4 543.5 1015.7 59.8 0.5 155.9 23.1 0.0 2440.7 779.6 20.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 1.7 0.4 1.7 0.0 0.0 1.6 1.5 2.7 0.0 0.0 4.6 5.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.0 0.1 0.8 1.8 0.2 0.7 0.0 1.3 0.0 0.8 0.4 0.3 0.7 0.1 0.2 545.0 0.4 0.1 0.5 794.2 0.2 0.1 14.9 0.3 0.6 0.3 0.3 76.5 0.2 0.2 0.1 1.7 0.2 0.3 1.8 0.2 0.6 0.4 0.5 0.6 0.0 0.0 0.0 0.0 84.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.0 1.9 40.8 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17441.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 417.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 IGLV2-23 ENSG00000211660 "Immunoglobulin lambda variable 2-23" P01705 22 22697789-22698407 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 691.1;lymphoid tissue: 1598.0;stomach 1: 672.8" "Cell type enriched" "Detected in some" 132 "Plasma cells: 12487.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 369 "memory B-cell: 2072.7;naive B-cell: 2596.0" "Lineage enriched" "Detected in all" 410 "B-cells: 2596.0" "Cell line enriched" "Detected in some" 10 "Karpas-707: 85411.7" "Immunoglobulin genes" NA NA 540000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.43e-5)" "unprognostic (7.99e-2)" "unprognostic (3.89e-2)" "unprognostic (2.35e-3)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (9.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (8.20e-2)" "unprognostic (7.79e-2)" "unprognostic (1.20e-1)" "unprognostic (7.42e-2)" 16.0 38.9 0.7 306.7 0.3 103.6 184.7 0.1 1.5 45.2 0.6 634.1 691.1 16.2 1.3 78.7 25.5 66.8 19.9 0.2 0.1 18.6 26.2 160.8 623.2 1.0 0.1 16.3 8.2 0.6 1.7 0.6 0.4 10.8 457.1 0.0 356.7 38.1 0.5 2.1 517.3 16.1 0.3 530.5 672.8 5.9 0.2 277.6 39.1 0.4 1598.0 274.5 11.9 0.3 0.8 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 65.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.3 82.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 85411.7 0.0 0.0 2.2 4.2 0.5 0.0 0.0 0.7 1.9 8843.9 0.0 0.0 2.1 4.5 0.0 4.7 0.0 0.0 1.9 0.0 1.0 0.0 1.1 3.4 0.7 213.9 81.1 0.5 92.6 0.2 35.5 1.8 3.1 1.0 1.6 0.9 1.3 2072.7 1.6 0.8 2.6 2596.0 0.6 0.9 6.3 1.6 1.7 0.9 1.3 231.7 0.7 0.3 0.1 1.5 0.2 0.1 1.0 0.1 0.4 0.3 0.2 0.3 0.0 0.0 0.0 0.0 94.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.7 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12487.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 39.5 0.0 0.2 0.0 IGLV3-22 ENSG00000211661 "Immunoglobulin lambda variable 3-22" A0A075B6J6 22 22704265-22704822 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.6;lymphoid tissue: 9.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 72 "memory B-cell: 6.6;naive B-cell: 7.7" "Lineage enriched" "Detected in single" 78 "B-cells: 7.7" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 1100000000 "Cluster 37: B-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "unprognostic (2.00e-1)" "unprognostic (9.93e-3)" "unprognostic (3.73e-1)" 0.0 0.7 0.0 1.0 0.0 1.5 2.6 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.8 0.3 0.0 0.0 1.4 0.0 0.0 1.4 0.8 0.3 0.0 9.5 0.0 0.0 5.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-21 ENSG00000211662 "Immunoglobulin lambda variable 3-21" P80748 22 22711689-22713203 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1812.1;urinary bladder: 773.9" "Cell type enriched" "Detected in some" 59 "Plasma cells: 5013.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 339 "memory B-cell: 432.0;naive B-cell: 224.7" "Lineage enriched" "Detected in single" 445 "B-cells: 432.0" "Cell line enriched" "Detected in some" 103 "REH: 282.7" "Immunoglobulin genes" NA NA 4700000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.75e-3)" "unprognostic (6.04e-3)" "unprognostic (4.21e-2)" "unprognostic (2.59e-3)" "unprognostic (4.06e-3)" "prognostic favorable (3.26e-7)" "unprognostic (1.63e-1)" "unprognostic (1.78e-1)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (3.86e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (9.54e-8)" "unprognostic (7.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.67e-1)" "unprognostic (7.52e-2)" 17.6 63.4 0.3 321.9 0.2 248.2 120.7 0.1 1.6 110.0 1.6 357.4 350.4 12.9 0.5 63.1 10.2 120.4 10.8 0.1 0.2 21.5 36.4 108.6 272.7 1.0 0.1 35.6 5.7 0.7 1.4 0.4 0.4 16.8 230.8 0.0 260.8 20.2 0.5 2.3 150.7 9.0 0.3 421.0 504.5 14.4 0.3 171.6 19.9 0.0 1812.1 773.9 17.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.4 0.5 0.2 0.0 0.0 282.7 1.8 2.0 0.0 0.0 1.6 1.8 0.1 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.5 0.5 0.5 0.1 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.1 0.0 0.1 432.0 0.1 0.1 0.3 224.7 0.1 0.1 0.9 0.1 0.1 0.2 0.1 36.6 0.3 0.2 0.1 1.6 0.1 0.2 1.0 0.1 0.4 0.3 0.3 1.3 0.0 0.0 0.0 0.0 84.4 0.0 0.0 0.0 4.6 0.0 0.1 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 20.4 0.0 0.0 0.0 3.3 2.5 0.1 0.0 0.0 0.0 0.0 1.3 0.0 4.7 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5013.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.2 0.0 0.0 1.8 0.0 0.2 0.0 IGLV3-19 ENSG00000211663 "Immunoglobulin lambda variable 3-19" P01714 22 22720623-22721145 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1026.7;lymphoid tissue: 1979.7;stomach 1: 1240.2" "Cell type enriched" "Detected in some" 61 "Plasma cells: 3121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 355 "memory B-cell: 618.3;naive B-cell: 503.7" "Lineage enriched" "Detected in many" 391 "B-cells: 618.3" "Cell line enhanced" "Detected in some" "RPMI-8226: 6.2;SCLC-21H: 9.4;SH-SY5Y: 10.7;U-251 MG: 4.2" "Immunoglobulin genes" NA NA 1200000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.92e-5)" "unprognostic (1.52e-2)" "unprognostic (1.60e-3)" "prognostic favorable (6.11e-5)" "unprognostic (1.14e-1)" "unprognostic (1.24e-3)" "unprognostic (9.58e-3)" "unprognostic (3.57e-1)" "unprognostic (1.55e-1)" "unprognostic (1.00e-1)" "unprognostic (3.13e-1)" "unprognostic (3.03e-1)" "prognostic unfavorable (9.37e-10)" "unprognostic (2.10e-1)" "unprognostic (2.31e-1)" "unprognostic (2.44e-1)" "unprognostic (8.52e-2)" 49.1 20.1 0.1 402.2 0.3 185.1 313.5 0.1 2.4 69.2 0.3 1026.7 713.6 19.0 263.4 154.0 65.8 182.4 36.9 0.1 0.3 26.0 57.5 192.2 464.9 1.5 0.4 44.9 11.5 1.3 2.7 0.4 0.4 17.2 912.2 0.0 304.9 62.4 0.9 4.8 385.2 34.9 0.6 714.2 1240.2 6.0 0.4 435.0 55.4 0.0 1979.7 642.5 13.6 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 2.7 0.3 0.0 0.0 0.1 0.9 6.2 0.0 0.0 9.4 10.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.4 0.0 4.2 0.8 0.5 0.7 0.0 0.5 0.0 0.4 0.4 1.0 0.5 0.3 0.7 618.3 0.2 0.3 0.5 503.7 0.4 0.3 1.5 0.3 0.4 0.6 0.4 36.2 0.1 0.3 0.1 2.4 0.1 0.3 1.5 0.4 0.4 0.6 0.4 1.1 0.0 0.0 0.0 0.0 51.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.4 15.8 0.0 1.3 0.0 2.2 1.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3121.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 IGLV2-18 ENSG00000211664 "Immunoglobulin lambda variable 2-18" A0A075B6J9 22 22734607-22735089 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 271.5;lymphoid tissue: 224.4" "Cell type enriched" "Detected in some" 210 "Plasma cells: 2488.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 44 "memory B-cell: 321.2;naive B-cell: 126.9" "Lineage enriched" "Detected in many" 64 "B-cells: 321.2" "Group enriched" "Detected in some" 7 "RPMI-8226: 13.4;U-266/70: 22.3;U-266/84: 7.2" "Immunoglobulin genes" NA NA 570000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (6.06e-5)" "unprognostic (2.81e-2)" "unprognostic (7.47e-3)" "unprognostic (1.13e-2)" "prognostic favorable (7.75e-4)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (7.58e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.86e-7)" "unprognostic (1.95e-1)" "unprognostic (9.70e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-2)" 3.4 0.3 0.0 73.0 0.0 23.7 67.1 0.0 0.3 6.7 0.1 271.5 262.0 4.2 0.0 39.6 10.8 36.3 12.5 0.0 0.0 2.0 2.8 12.6 37.6 0.1 0.0 4.1 1.1 2.1 0.2 0.1 0.4 1.7 138.6 0.0 64.3 4.9 0.1 0.3 150.2 6.5 0.0 95.8 72.5 0.5 0.0 22.1 2.8 0.0 224.4 18.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 13.4 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.3 7.2 0.1 0.1 0.1 0.0 0.2 1.8 0.0 1.6 0.0 0.8 321.2 0.3 1.3 0.1 126.9 0.7 0.6 0.5 5.0 0.1 0.2 0.1 69.7 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 7.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2488.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 IGLV3-16 ENSG00000211665 "Immunoglobulin lambda variable 3-16" A0A075B6K0 22 22747383-22747921 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 80.3;urinary bladder: 42.9" "Group enriched" "Detected in some" 49 "B-cells: 6.2;Plasma cells: 3.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 393 "memory B-cell: 107.2;naive B-cell: 121.2" "Lineage enriched" "Detected in single" 417 "B-cells: 121.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 350000000 "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 57: B-cells - Immune response" "prognostic favorable (5.01e-5)" "unprognostic (2.40e-3)" "unprognostic (4.30e-3)" "unprognostic (4.05e-1)" "prognostic favorable (2.99e-5)" "unprognostic (3.88e-1)" "unprognostic (1.12e-1)" "unprognostic (9.83e-2)" "unprognostic (9.82e-2)" "prognostic unfavorable (9.08e-7)" "unprognostic (4.31e-2)" "unprognostic (3.41e-1)" "unprognostic (7.02e-2)" "unprognostic (1.60e-1)" 1.5 0.0 0.0 6.9 0.0 6.3 4.9 0.0 0.0 0.7 0.0 10.7 9.9 0.2 0.0 2.5 1.9 1.2 0.6 0.0 0.0 0.7 1.3 4.7 13.6 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 1.6 10.8 0.0 10.8 0.0 0.0 0.1 5.2 0.6 0.0 12.8 13.0 0.3 0.0 3.5 0.2 0.0 80.3 42.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 107.2 0.0 0.1 0.1 121.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-14 ENSG00000211666 "Immunoglobulin lambda variable 2-14" P01704 22 22758700-22759218 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 2622.2;lymphoid tissue: 5374.9;stomach 1: 2530.1" "Cell type enriched" "Detected in some" 179 "Plasma cells: 58316.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 50 "memory B-cell: 3655.3;naive B-cell: 2657.4" "Lineage enriched" "Detected in all" 58 "B-cells: 3655.3" "Cell line enriched" "Detected in many" 5 "RPMI-8226: 22672.4" "Immunoglobulin genes" NA NA 2200000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (3.23e-4)" "unprognostic (9.05e-3)" "unprognostic (1.18e-2)" "unprognostic (7.20e-3)" "unprognostic (2.00e-2)" "prognostic favorable (2.21e-4)" "unprognostic (3.69e-1)" "unprognostic (1.97e-1)" "unprognostic (7.99e-2)" "unprognostic (1.83e-2)" "unprognostic (9.11e-2)" "unprognostic (4.97e-1)" "prognostic unfavorable (5.74e-7)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.87e-2)" 83.9 192.1 0.8 754.9 1.7 357.8 749.8 0.5 6.4 119.7 3.8 2622.2 2470.7 47.8 20.7 245.2 49.0 442.1 45.2 0.6 1.0 54.3 102.1 399.3 3320.0 1.6 0.6 75.3 52.1 4.5 5.6 1.2 1.0 71.0 1074.1 0.1 797.3 119.4 2.7 21.3 1262.7 62.0 1.4 1580.6 2530.1 13.9 1.3 586.1 116.5 0.5 5374.9 1165.2 35.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.4 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.8 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4453.2 0.0 0.0 8.7 8.0 1.7 0.0 0.0 4.9 3.7 22672.4 0.0 0.0 11.8 11.1 0.4 17.3 0.0 0.0 7.1 0.0 5.1 0.0 4.1 5.7 1.1 20.4 37.7 1.4 12.1 1.7 5.0 3.9 5.3 1.7 47.1 1.0 28.8 3655.3 9.6 53.9 3.3 2657.4 1.4 12.7 11.6 62.5 2.4 2.2 2.1 451.3 0.8 1.7 0.5 6.4 0.6 1.0 1.6 0.6 1.0 1.4 1.3 2.1 0.0 0.0 0.0 0.0 324.1 0.0 0.0 0.0 1.2 0.0 0.3 0.3 0.0 2.8 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 14.7 0.0 0.0 0.0 9.9 121.8 0.0 0.0 0.0 1.4 1.7 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 58316.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 36.6 0.0 0.8 0.0 IGLV3-12 ENSG00000211667 "Immunoglobulin lambda variable 3-12" A0A075B6K2 22 22771824-22772582 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 4.2;memory B-cell: 9.2;memory CD8 T-cell: 4.0;naive B-cell: 6.7;NK-cell: 5.6" "Group enriched" "Detected in many" 64 "B-cells: 9.2;NK-cells: 5.6;T-cells: 4.2" "Not detected" "Not detected" "Immunoglobulin genes" NA NA 850000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.92e-3)" "unprognostic (4.30e-2)" "unprognostic (1.68e-3)" "unprognostic (2.03e-2)" "prognostic favorable (8.39e-6)" "unprognostic (8.44e-2)" "unprognostic (4.62e-2)" "unprognostic (5.01e-2)" "unprognostic (2.88e-2)" "unprognostic (3.15e-4)" "unprognostic (3.62e-2)" "unprognostic (4.71e-1)" "unprognostic (3.14e-1)" "unprognostic (1.52e-1)" 0.8 1.2 0.0 3.9 0.0 2.7 1.9 0.0 0.3 0.3 0.1 7.3 5.5 0.5 0.0 1.0 0.6 3.3 0.0 0.0 0.0 0.1 0.5 2.7 15.3 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 3.8 0.0 5.1 1.7 0.0 0.2 2.7 0.1 0.0 4.6 8.2 0.9 0.0 3.9 0.2 0.0 30.1 1.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 1.1 9.2 1.0 4.0 0.0 6.7 0.0 0.2 0.0 5.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV2-11 ENSG00000211668 "Immunoglobulin lambda variable 2-11" P01706 22 22792491-22793007 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1542.6;lymphoid tissue: 2926.9" "Cell type enriched" "Detected in some" 85 "Plasma cells: 7693.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 37 "memory B-cell: 1402.5;naive B-cell: 850.1" "Lineage enriched" "Detected in many" 46 "B-cells: 1402.5" "Cell line enhanced" "Detected in some" "Karpas-707: 75.0;U-266/70: 20.9;U-266/84: 15.3" "Immunoglobulin genes" NA NA 980000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (9.76e-3)" "unprognostic (6.86e-2)" "unprognostic (3.46e-3)" "unprognostic (7.67e-3)" "unprognostic (2.82e-3)" "prognostic favorable (4.74e-5)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (9.19e-2)" "unprognostic (1.77e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.38e-7)" "unprognostic (3.93e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (2.27e-1)" 33.6 7.3 0.6 344.7 0.3 157.3 447.8 0.1 2.7 27.7 0.8 1455.8 1542.6 18.4 0.5 212.0 30.0 191.3 44.6 0.2 0.7 22.4 41.1 179.8 680.1 1.5 0.2 30.5 22.4 0.6 2.1 0.5 1.1 17.0 868.3 0.0 425.0 36.0 1.7 2.9 713.8 21.3 0.6 637.7 876.1 75.4 0.5 286.4 62.2 0.0 2926.9 661.1 14.8 2.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 3.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 75.0 0.0 0.0 0.9 4.6 1.1 0.0 0.0 0.8 2.8 8.3 0.0 0.0 2.9 4.8 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 1.1 0.3 1.6 20.9 15.3 0.0 0.3 1.1 0.0 1.2 1.0 0.7 11.5 0.2 1.4 1402.5 1.5 5.9 0.9 850.1 1.0 4.6 30.2 11.1 0.8 0.9 0.8 149.8 0.6 0.3 0.1 2.7 0.2 0.7 1.5 0.2 1.1 0.6 0.5 2.2 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 15.8 0.0 0.0 0.0 1.4 11.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7693.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 IGLV3-10 ENSG00000211669 "Immunoglobulin lambda variable 3-10" A0A075B6K4 22 22811747-22812281 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 317.0;lymphoid tissue: 707.7;stomach 1: 288.7" "Cell type enriched" "Detected in some" 52 "Plasma cells: 1090.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebral cortex: 3.3;medulla oblongata: 1.8" "Group enriched" "Detected in some" 786 "memory B-cell: 548.7;naive B-cell: 315.0" "Lineage enriched" "Detected in single" 998 "B-cells: 548.7" "Cell line enhanced" "Detected in some" "Daudi: 4.9;HL-60: 1.0;RH-30: 1.6" HPA003285 Approved "Immunoglobulin genes" NA NA 2000000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "unprognostic (6.00e-2)" "unprognostic (2.28e-2)" "unprognostic (1.65e-2)" "unprognostic (1.73e-2)" "unprognostic (6.99e-2)" "prognostic favorable (1.27e-4)" "unprognostic (7.40e-3)" "unprognostic (2.44e-2)" "unprognostic (9.91e-2)" "unprognostic (9.55e-2)" "unprognostic (2.79e-1)" "unprognostic (3.55e-1)" "prognostic unfavorable (6.95e-8)" "unprognostic (9.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.77e-1)" "unprognostic (6.04e-2)" 33.3 112.9 0.5 144.0 0.4 65.5 111.1 0.1 3.3 41.3 0.6 308.0 176.3 7.6 4.5 56.3 7.9 43.5 20.5 0.1 0.2 12.2 20.8 48.0 230.5 1.8 0.2 14.6 10.8 0.9 0.8 0.4 0.6 11.0 317.0 0.0 139.7 10.8 0.2 8.1 94.9 5.8 0.1 217.1 288.7 97.4 0.2 25.9 8.6 0.0 707.7 140.2 7.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.2 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.2 0.0 0.2 548.7 0.1 0.2 0.2 315.0 0.0 0.2 0.3 0.1 0.1 0.3 0.1 43.2 0.5 0.4 0.1 3.3 0.1 0.2 1.8 0.2 0.6 0.1 0.2 0.2 0.0 0.0 0.6 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 7.1 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1090.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.2 0.0 IGLV3-9 ENSG00000211670 "Immunoglobulin lambda variable 3-9" A0A075B6K5 22 22819010-22819756 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 313.9;stomach 1: 117.3" "Cell type enriched" "Detected in some" 9 "Plasma cells: 13.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 51 "memory B-cell: 64.7;naive B-cell: 168.7" "Lineage enriched" "Detected in many" 74 "B-cells: 168.7" "Cell line enriched" "Detected in some" 5 "U-266/70: 41.3" HPA003285 Approved "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (2.59e-4)" "unprognostic (6.52e-3)" "unprognostic (1.95e-1)" "unprognostic (5.40e-2)" "prognostic favorable (9.80e-5)" "unprognostic (1.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.68e-1)" "unprognostic (1.50e-1)" "unprognostic (2.52e-2)" "unprognostic (3.29e-1)" "prognostic unfavorable (6.00e-7)" "unprognostic (3.47e-2)" "unprognostic (4.58e-2)" "unprognostic (4.55e-2)" "unprognostic (3.22e-1)" 1.8 23.5 0.1 84.6 0.0 27.8 14.9 0.0 0.1 7.3 0.1 87.1 58.7 2.0 0.0 20.8 1.8 18.6 7.6 0.0 0.0 3.2 6.2 17.1 139.8 0.7 0.0 3.9 2.4 0.2 0.1 0.0 0.1 1.4 64.0 0.0 46.2 3.1 0.1 1.5 60.3 5.2 0.0 64.6 117.3 1.6 0.1 35.0 3.8 0.0 313.9 72.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 2.1 0.1 0.3 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.9 0.3 0.0 41.3 5.8 0.7 0.0 3.9 0.0 0.0 0.1 0.0 1.2 0.0 2.2 64.7 1.3 1.4 0.0 168.7 0.4 1.8 0.1 0.5 0.1 0.0 0.1 6.5 0.1 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 IGLV2-8 ENSG00000278196 "Immunoglobulin lambda variable 2-8" P01709 22 22822658-22823289 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1141.8;lymphoid tissue: 1012.4" "Cell type enriched" "Detected in some" 80 "Plasma cells: 5288.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 125 "memory B-cell: 1439.0;naive B-cell: 2097.3" "Lineage enriched" "Detected in all" 149 "B-cells: 2097.3" "Group enriched" "Detected in many" 617 "U-266/70: 64161.5;U-266/84: 56786.5" "Immunoglobulin genes" NA NA 1500000000 "Cluster 24: B-cells - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (2.92e-4)" "unprognostic (1.29e-1)" "unprognostic (7.17e-3)" "unprognostic (1.05e-2)" "unprognostic (1.65e-1)" "prognostic favorable (5.07e-5)" "unprognostic (2.74e-2)" "unprognostic (1.51e-1)" "unprognostic (1.34e-1)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (6.55e-2)" "prognostic unfavorable (3.00e-5)" "unprognostic (2.04e-2)" "unprognostic (2.67e-1)" "unprognostic (9.90e-2)" "unprognostic (1.62e-1)" 18.7 7.0 1.1 325.0 0.6 96.0 155.2 0.3 2.4 26.0 1.7 1141.8 977.0 9.4 3.5 91.4 7.9 132.4 30.5 0.3 0.3 15.4 24.3 59.2 228.2 0.8 0.3 57.2 30.3 1.4 1.4 0.2 0.7 9.0 250.6 0.0 255.5 60.3 0.6 1.9 451.5 20.1 0.8 437.7 433.9 3.4 0.3 90.6 23.7 0.0 1012.4 259.0 10.3 1.0 62.7 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 7.6 0.0 0.0 23.1 0.0 0.0 0.0 22.3 0.0 0.5 0.0 0.0 0.0 0.7 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 0.0 0.0 11.3 1.9 14.8 0.0 0.0 97.9 0.9 10.1 0.0 0.0 1.4 2.8 0.2 0.0 9.3 0.0 0.0 29.5 0.9 0.0 9.8 0.6 38.9 64161.5 56786.5 20.4 0.0 10.1 0.0 1.2 2.4 0.6 2.1 0.7 0.9 1439.0 1.3 1.5 1.9 2097.3 0.4 1.0 14.1 1.3 1.4 0.6 0.7 174.0 1.1 0.6 0.3 2.4 0.3 0.3 0.8 0.3 0.7 0.8 0.3 1.0 0.0 3.2 0.0 0.0 65.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 2.5 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5288.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.0 0.2 0.0 IGLV4-3 ENSG00000211672 "Immunoglobulin lambda variable 4-3" A0A075B6K6 22 22871507-22872035 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "lymphoid tissue: 15.7;stomach 1: 28.9" "Cell type enriched" "Detected in some" 23 "Plasma cells: 50.3" "Cancer enhanced" "Detected in many" "lung cancer: 4.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 98 "memory B-cell: 11.7;naive B-cell: 7.8" "Lineage enriched" "Detected in single" 118 "B-cells: 11.7" "Cell line enriched" "Detected in single" 5 "Daudi: 1.3" "Immunoglobulin genes" NA NA 1600000 "Cluster 37: B-cells - Transcription" "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (7.22e-2)" "unprognostic (5.51e-3)" "unprognostic (2.71e-1)" "unprognostic (4.37e-4)" "unprognostic (1.87e-1)" "unprognostic (2.74e-1)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" 0.2 0.0 0.0 2.1 0.0 1.4 1.6 0.0 0.0 0.3 0.0 5.1 4.5 0.3 0.0 0.3 0.1 0.4 0.0 0.0 0.0 0.1 0.1 1.0 10.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 3.3 0.0 2.8 0.0 0.0 0.0 3.0 0.0 0.0 5.3 28.9 0.2 0.0 1.4 0.4 0.0 15.7 0.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLV3-1 ENSG00000211673 "Immunoglobulin lambda variable 3-1" P01715 22 22880706-22881396 "Immunoglobulin genes, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1234.9;lymphoid tissue: 3325.7;stomach 1: 1460.4" "Cell type enriched" "Detected in some" 321 "Plasma cells: 56277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 725 "memory B-cell: 779.5;naive B-cell: 1038.5" "Lineage enriched" "Detected in many" 828 "B-cells: 1038.5" "Cell line enhanced" "Detected in some" "Daudi: 14.4;RPMI-8226: 4.5;SCLC-21H: 9.1;SH-SY5Y: 9.9" HPA003285 Approved "Immunoglobulin genes" NA NA 4300000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA003285: AB_1079122" "prognostic favorable (9.70e-5)" "unprognostic (9.06e-2)" "unprognostic (5.39e-3)" "unprognostic (2.37e-2)" "unprognostic (8.13e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.30e-2)" "unprognostic (1.21e-1)" "unprognostic (1.92e-2)" "unprognostic (1.63e-2)" "unprognostic (2.86e-1)" "unprognostic (2.82e-1)" "prognostic unfavorable (9.06e-9)" "unprognostic (2.70e-2)" "unprognostic (4.35e-1)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" 44.5 70.9 0.3 485.2 0.2 332.4 317.1 0.2 2.0 192.0 0.9 1234.9 643.4 39.2 0.0 217.7 19.2 310.4 28.1 0.1 0.4 26.3 70.1 176.2 1117.0 1.0 0.3 34.1 7.6 2.7 2.0 0.7 1.5 21.9 684.4 0.2 627.3 19.6 1.2 4.1 481.7 37.2 0.4 654.2 1460.4 56.0 0.3 335.5 35.9 0.0 3325.7 679.7 30.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.1 0.0 0.0 1.1 0.0 0.0 0.0 1.9 0.0 0.6 0.0 0.0 0.0 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.2 2.4 0.8 0.0 0.0 0.5 3.0 4.5 0.0 0.0 9.1 9.9 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.6 0.6 1.7 1.8 1.2 2.8 0.0 0.3 0.0 0.7 1.1 0.5 0.3 0.4 0.4 779.5 0.6 0.2 1.2 1038.5 0.2 0.3 0.6 0.4 0.8 0.5 0.5 52.3 0.3 0.2 0.2 2.0 0.1 0.4 1.0 0.3 1.5 0.4 0.3 0.9 0.0 3.2 0.0 0.0 111.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122.5 0.0 0.0 0.0 0.0 0.0 10.7 174.8 0.0 0.0 0.0 1.1 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 56277.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 11.7 0.0 0.2 0.0 IGLL5 ENSG00000254709 "Immunoglobulin lambda like polypeptide 5" B9A064 22 22887780-22896111 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 408.3;lymphoid tissue: 674.1;stomach 1: 308.1" "Cell type enriched" "Detected in some" 55 "Melanocytes: 93931.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 226 "memory B-cell: 515.9;naive B-cell: 615.5" "Lineage enriched" "Detected in many" 246 "B-cells: 615.5" "Group enriched" "Detected in some" 7 "Daudi: 637.2;U-266/70: 386.4;U-698: 441.1" "Secreted to blood" NA NA 53000000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "prognostic favorable (6.10e-4)" "unprognostic (7.64e-3)" "unprognostic (4.33e-2)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "prognostic favorable (3.41e-5)" "unprognostic (1.76e-2)" "unprognostic (2.18e-1)" "unprognostic (7.28e-2)" "unprognostic (1.87e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (5.94e-8)" "unprognostic (1.85e-1)" "unprognostic (4.63e-1)" "unprognostic (8.52e-2)" "unprognostic (6.50e-2)" 16.3 25.1 0.3 164.8 0.2 94.4 139.3 0.1 1.2 32.8 0.4 405.6 408.3 7.8 0.0 50.4 14.7 67.3 11.2 0.1 0.1 17.0 15.9 65.7 308.5 0.4 0.1 18.6 11.0 1.5 1.5 0.2 0.2 8.3 249.4 0.1 279.3 22.2 0.5 2.7 181.5 8.8 0.4 458.8 308.1 4.3 0.2 123.6 26.2 0.2 674.1 223.5 10.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 637.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 3.6 0.9 0.0 0.0 0.6 1.0 0.4 0.0 0.1 0.0 0.0 0.9 1.4 0.0 1.9 0.1 0.2 386.4 68.5 441.1 0.0 0.3 0.0 0.4 0.7 0.2 0.3 0.1 0.2 515.9 0.2 0.2 0.8 615.5 0.1 0.2 1.0 0.2 0.4 2.5 0.3 68.1 0.3 0.2 0.1 1.2 0.1 0.1 0.4 0.1 0.2 0.4 0.2 0.5 0.0 3.2 30.9 0.0 222.5 108.6 0.0 0.0 0.0 0.0 1.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 12.7 1.2 5.7 0.0 0.0 0.0 7.7 3.1 0.0 11.4 0.1 1.1 4.2 0.0 0.0 0.0 0.1 0.0 0.8 113.1 3.8 0.0 0.9 93931.2 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 1680.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 93.5 0.0 49.3 0.0 2.4 0.0 IGLJ1 ENSG00000211674 "Immunoglobulin lambda joining 1" A0A0A0MT76 22 22893692-22893818 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 6 "intestine: 95.1;lymphoid tissue: 50.0;salivary gland: 32.5;stomach 1: 40.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "memory B-cell: 19.6;naive B-cell: 11.0" "Lineage enriched" "Detected in single" 31 "B-cells: 19.6" "Group enriched" "Detected in some" 6 "Daudi: 274.6;U-266/70: 310.0;U-698: 88.7" "Immunoglobulin genes" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "unprognostic (4.18e-4)" "unprognostic (4.80e-3)" "unprognostic (6.97e-2)" "unprognostic (4.68e-1)" 2.3 0.6 0.1 43.3 0.1 9.8 1.8 0.2 0.6 0.0 0.4 17.1 95.1 0.8 0.0 2.0 0.4 5.1 0.2 0.0 0.1 0.2 0.1 2.7 50.0 0.5 0.1 0.5 0.0 0.0 0.0 0.2 0.3 0.6 13.5 0.0 32.5 0.0 0.0 0.0 43.4 2.6 0.2 31.5 40.8 1.3 0.2 5.2 0.0 0.0 34.5 4.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 274.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.3 3.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 310.0 37.0 88.7 0.0 0.9 0.0 0.0 0.1 0.1 0.1 0.0 0.0 19.6 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.1 0.1 0.2 0.6 0.0 0.1 0.5 0.1 0.3 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC1 IGLC ENSG00000211675 "Immunoglobulin lambda constant 1" 22 22895375-22895834 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 3264.2;lymphoid tissue: 5586.9;stomach 1: 2335.3" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 37.3;granulocytes: 15.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 743 "memory B-cell: 5729.2;naive B-cell: 5821.4" "Lineage enriched" "Detected in all" 749 "B-cells: 5821.4" "Cell line enriched" "Detected in many" 5 "U-266/70: 600.3" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" 132.3 163.1 2.2 1208.8 1.9 641.9 903.4 1.7 7.0 190.8 4.4 3038.0 3264.2 63.1 2.1 535.0 113.2 640.0 104.5 1.7 2.2 148.2 114.7 470.6 2372.4 3.9 1.7 135.6 69.8 8.0 13.2 1.9 2.2 71.5 2133.6 0.7 2047.0 124.0 4.9 28.8 1389.9 78.0 2.6 3332.0 2335.3 23.7 2.3 873.2 224.5 0.0 5586.9 1948.8 79.3 3.4 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 1.0 0.0 1.9 0.2 0.0 0.0 6.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 9.1 0.0 0.0 1.1 10.2 2.0 0.0 0.0 2.3 8.9 33.4 0.0 0.0 6.3 11.1 1.4 0.0 0.0 0.0 0.0 0.3 2.5 0.0 1.3 4.3 2.6 600.3 119.9 36.5 0.0 3.5 0.0 4.2 7.7 2.0 3.7 1.7 2.9 5729.2 3.8 2.5 6.0 5821.4 0.9 2.2 7.6 2.8 4.8 5.2 3.4 897.2 2.2 1.9 1.7 7.0 1.7 2.2 3.9 1.7 2.2 2.6 2.3 3.4 0.0 6.4 37.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 IGLJ2 ENSG00000211676 "Immunoglobulin lambda joining 2" 22 22899481-22899655 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 260.8;lymphoid tissue: 189.8;stomach 1: 212.7" "Cell type enriched" "Detected in single" 5 "Plasma cells: 1.7" "Group enriched" "Detected in many" 8 "colorectal cancer: 12.9;endometrial cancer: 21.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "memory B-cell: 876.1;naive B-cell: 864.5" "Lineage enriched" "Detected in many" 12 "B-cells: 876.1" "Cell line enhanced" "Detected in some" "Daudi: 10.8;HMC-1: 34.1;RH-30: 89.7;U-698: 19.8" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.99e-3)" "unprognostic (5.36e-2)" "unprognostic (5.54e-2)" "unprognostic (1.13e-2)" "unprognostic (5.94e-7)" "unprognostic (1.51e-2)" "unprognostic (3.63e-2)" "unprognostic (3.66e-2)" "unprognostic (5.17e-2)" "unprognostic (2.92e-1)" 8.4 54.9 0.2 173.0 0.0 25.4 11.2 0.1 0.8 6.1 0.1 134.5 260.8 2.9 4.2 13.5 1.0 12.5 2.9 0.1 0.2 2.1 6.9 21.5 94.5 0.3 0.0 4.7 5.9 0.1 0.0 0.0 0.9 4.0 31.1 0.0 75.6 4.2 0.0 0.2 206.0 1.9 0.1 128.3 212.7 2.3 0.0 15.5 0.3 0.0 189.8 60.8 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.7 89.7 1.3 0.0 0.0 0.8 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.0 0.0 0.6 19.8 0.0 0.5 0.0 1.4 1.9 0.6 0.4 0.2 0.7 876.1 0.3 0.3 0.9 864.5 0.2 0.4 9.3 0.7 0.8 71.8 0.5 136.5 0.2 0.0 0.1 0.8 0.1 0.2 0.3 0.0 0.9 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC2 IGLC ENSG00000211677 "Immunoglobulin lambda constant 2" P0DOY2 22 22900976-22901437 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 9734.6;lymphoid tissue: 19988.7;stomach 1: 10849.9" "Group enriched" "Detected in many" 40 "B-cells: 24632.2;Plasma cells: 18795.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 36 "memory B-cell: 11361.1;naive B-cell: 10650.3" "Lineage enriched" "Detected in all" 37 "B-cells: 11361.1" "Group enriched" "Detected in many" 190 "RPMI-8226: 62032.1;U-266/70: 102644.1;U-266/84: 83511.6" "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "prognostic favorable (5.76e-5)" "unprognostic (2.29e-2)" "unprognostic (4.54e-3)" "unprognostic (1.46e-2)" "unprognostic (4.02e-2)" "prognostic favorable (1.14e-4)" "unprognostic (1.96e-2)" "unprognostic (7.52e-2)" "unprognostic (7.15e-2)" "unprognostic (7.69e-3)" "unprognostic (2.83e-1)" "unprognostic (4.41e-2)" "prognostic unfavorable (4.47e-9)" "unprognostic (2.00e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" 386.6 782.7 7.7 3871.2 6.2 2741.4 2183.6 4.6 14.9 815.5 11.4 8217.0 9734.6 194.3 207.0 1690.0 231.5 2091.8 318.3 4.6 5.7 301.6 382.3 1442.8 5543.4 11.1 5.0 540.2 112.7 16.8 31.0 7.5 6.6 264.0 5055.4 0.7 5934.2 384.9 8.6 74.2 5290.6 306.2 6.6 7090.0 10849.9 256.0 5.4 2071.4 491.7 0.6 19988.7 6482.1 176.7 10.7 120.6 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 221.4 12.0 0.0 0.0 61.9 0.0 0.0 0.0 30.5 0.0 7.7 0.0 0.0 0.0 19.2 343.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 64.7 0.0 0.0 70.1 27.7 52.3 0.0 0.0 45.3 436.2 62032.1 0.0 0.0 46.7 45.7 5.6 43.0 17.3 0.0 17.7 57.2 11.7 0.0 38.9 23.4 78.2 102644.1 83511.6 298.8 0.7 21.9 0.7 9.9 18.6 5.6 5.8 3.0 5.7 11361.1 5.8 4.5 10.9 10650.3 3.5 4.7 118.0 5.8 8.7 303.3 6.5 2385.6 7.7 6.2 4.6 14.9 4.6 5.7 11.1 5.0 6.6 6.6 5.4 10.7 4.1 32.1 121.0 0.0 24632.2 0.0 0.3 0.0 1.2 0.0 16.1 3.0 3.9 44.3 8.1 0.0 0.0 0.3 8.0 28.0 0.0 0.0 0.0 0.0 0.1 86.3 62.5 222.4 0.0 0.0 0.3 42.5 14.8 0.0 65.6 0.0 222.8 539.9 2.1 0.0 0.0 21.5 0.0 134.5 0.0 0.0 0.0 8.5 0.0 0.0 11.4 0.0 15.5 0.0 0.0 0.0 20.6 0.0 18795.5 0.0 0.0 1.4 1.5 0.0 0.0 0.2 10.2 0.0 0.0 2.8 0.0 0.1 538.6 0.0 23.7 0.0 IGLJ3 ENSG00000211678 "Immunoglobulin lambda joining 3" 22 22904850-22905025 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 7 "intestine: 552.2;lymphoid tissue: 227.6;salivary gland: 149.1;stomach 1: 462.5;urinary bladder: 147.8" "Group enriched" "Detected in some" 44 "B-cells: 4.5;Plasma cells: 4.3" "Group enriched" "Detected in some" 13 "colorectal cancer: 5.1;endometrial cancer: 10.3" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Group enriched" "Detected in many" 24 "memory B-cell: 1223.9;naive B-cell: 1139.6" "Lineage enriched" "Detected in many" 25 "B-cells: 1223.9" "Group enriched" "Detected in some" 7 "Daudi: 53.6;REH: 69.6;U-266/70: 42.8;U-266/84: 22.5" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.19e-1)" "unprognostic (2.06e-3)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (5.00e-1)" 5.7 29.4 0.4 212.4 0.3 37.4 32.5 0.1 1.5 9.7 0.4 130.1 552.2 3.2 0.0 40.0 4.0 32.7 3.1 0.1 0.1 2.9 9.9 41.7 132.1 0.4 0.2 31.1 1.9 0.0 0.0 0.1 0.1 9.6 71.4 0.0 149.1 1.6 0.0 1.5 205.9 6.1 0.0 207.6 462.5 6.1 0.1 23.2 0.8 0.0 227.6 147.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 53.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 69.6 2.5 6.7 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 1.0 42.8 22.5 4.3 0.0 0.0 0.0 0.8 1.6 0.7 0.9 0.3 4.3 1223.9 0.8 0.5 1.3 1139.6 0.4 0.5 8.5 0.6 1.2 49.2 0.8 193.9 0.4 0.3 0.1 1.5 0.1 0.1 0.4 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC3 IGLC ENSG00000211679 "Immunoglobulin lambda constant 3 (Kern-Oz+ marker)" P0DOY3 22 22906342-22906803 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Bence-Jones protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 4115.7;lymphoid tissue: 8175.8;stomach 1: 4130.0;urinary bladder: 3726.3" "Group enriched" "Detected in many" 35 "B-cells: 12202.8;Plasma cells: 5357.3;T-cells: 3582.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 34 "memory B-cell: 7254.6;naive B-cell: 6119.2" "Lineage enriched" "Detected in all" 37 "B-cells: 7254.6" "Cell line enriched" "Detected in many" 15 "RPMI-8226: 10741.3" "CAB000050, CAB016533" Supported "Immunoglobulin genes" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "CAB000050: , CAB016533: AB_629719" "prognostic favorable (2.32e-4)" "unprognostic (1.18e-2)" "unprognostic (4.35e-3)" "unprognostic (4.54e-2)" "unprognostic (8.41e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.45e-2)" "unprognostic (4.59e-2)" "unprognostic (8.77e-2)" "prognostic favorable (4.58e-4)" "unprognostic (9.71e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.04e-9)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "unprognostic (1.37e-1)" "unprognostic (5.97e-2)" 156.2 550.9 2.6 2377.2 2.7 840.6 1388.6 1.4 9.1 220.4 7.1 4115.7 4046.3 115.2 33.2 508.5 88.0 707.7 63.7 1.3 2.8 178.6 171.7 1081.6 2745.8 7.2 1.4 247.8 47.6 7.0 19.0 3.2 2.0 134.0 2268.4 0.3 2264.0 177.1 5.8 20.7 2373.2 113.9 3.4 4261.5 4130.0 55.4 2.1 426.9 232.0 0.9 8175.8 3726.3 111.5 6.4 0.6 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 60.1 0.7 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 18.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 338.0 0.0 0.0 10.8 15.0 2.8 0.0 0.0 700.2 9.3 10741.3 0.0 0.0 16.6 25.1 4.4 20.8 0.0 0.0 4.9 0.8 11.1 0.0 6.3 7.2 5.0 88.0 103.4 36.1 1.2 5.3 0.5 6.4 9.1 3.9 6.0 2.0 27.3 7254.6 5.1 3.6 6.9 6119.2 2.6 3.3 60.7 4.3 4.6 195.3 4.7 1415.5 2.6 2.7 1.4 9.1 1.3 2.8 7.2 1.4 2.0 3.4 2.1 6.4 2.0 22.4 97.3 0.0 12202.8 0.0 0.7 0.0 0.0 0.0 5.4 0.5 15.3 8.6 3.7 0.0 0.0 0.2 8.8 5.0 0.0 0.0 0.0 0.0 0.1 7.4 12.2 54.8 0.0 0.0 0.0 22.1 5.6 0.1 47.9 0.0 195.9 127.7 0.2 0.0 0.0 3.5 0.0 23.1 0.0 0.0 0.0 5.6 0.0 0.0 2.0 0.0 2.1 0.0 0.0 0.0 3.1 0.0 5357.3 0.2 0.0 1.1 2.2 0.0 0.0 0.0 4.2 0.0 0.0 0.8 0.0 0.1 3582.0 0.0 6.3 0.9 IGLJ4 ENSG00000211680 "Immunoglobulin lambda joining 4 (non-functional)" 22 22910574-22910606 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 24 "brain: 1.3;intestine: 1.8;lymphoid tissue: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 34 "Daudi: 37.7;U-698: 13.3" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 1.8 0.0 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.3 0.5 0.1 0.0 1.0 0.2 1.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ5 ENSG00000211681 "Immunoglobulin lambda joining 5 (non-functional)" 22 22914237-22914308 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "breast: 1.6;lymphoid tissue: 3.8;stomach 1: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 117 "memory B-cell: 15.2;naive B-cell: 14.1;plasmacytoid DC: 5.7" "Group enriched" "Detected in many" 105 "B-cells: 15.2;dendritic cells: 5.7" "Group enriched" "Detected in some" 7 "Daudi: 32.4;U-698: 12.7" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.1 2.3 0.1 0.0 1.6 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 3.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.0 0.1 0.0 0.0 3.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.2 0.1 0.1 0.0 0.3 0.2 0.1 0.3 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ6 ENSG00000211682 "Immunoglobulin lambda joining 6" 22 22918132-22918201 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 6 "intestine: 6.6;lymphoid tissue: 7.9;urinary bladder: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "colorectal cancer: 1.2;endometrial cancer: 1.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "memory B-cell: 31.6;naive B-cell: 38.3" "Lineage enriched" "Detected in single" 52 "B-cells: 38.3" "Group enriched" "Detected in some" 8 "Daudi: 14.5;U-698: 4.3" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" 0.0 0.0 0.2 7.2 0.2 0.0 0.4 0.0 0.3 0.0 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 1.0 0.0 7.9 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.1 5.3 1.0 0.0 0.4 0.0 0.0 0.0 2.8 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.6 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.2 0.2 0.0 0.3 0.1 0.8 0.3 0.4 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLJ7 ENSG00000211684 "Immunoglobulin lambda joining 7" 22 22921390-22921435 "Immunoglobulin genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 12.3;lymphoid tissue: 19.0;stomach 1: 17.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "colorectal cancer: 1.0;endometrial cancer: 1.5" "Region enhanced" "Detected in some" "cerebral cortex: 3.4" "Group enriched" "Detected in some" 222 "memory B-cell: 314.0;naive B-cell: 370.8" "Lineage enriched" "Detected in many" 240 "B-cells: 370.8" "Cell line enriched" "Detected in single" 21 "U-266/70: 2.0" NA NA "Cluster 37: B-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" 0.7 4.1 0.1 14.5 0.1 1.1 0.0 0.3 3.4 0.0 0.0 6.1 12.3 0.0 0.0 2.1 0.0 3.3 0.0 0.2 0.9 0.0 0.0 2.0 3.0 1.2 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.8 1.9 0.0 5.9 0.0 0.0 0.0 5.4 0.0 0.0 3.8 17.5 1.8 0.1 0.3 0.0 0.0 19.0 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.0 0.6 314.0 0.0 0.0 0.0 370.8 0.0 0.0 0.0 0.0 1.5 0.2 0.0 27.6 0.1 0.1 0.3 3.4 0.2 0.9 1.2 0.4 0.7 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGLC7 ENSG00000211685 "Immunoglobulin lambda constant 7" 22 22922594-22923034 "Immunoglobulin genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 88.1;lymphoid tissue: 107.7;salivary gland: 70.1;stomach 1: 113.1" "Cell type enriched" "Detected in some" 10 "B-cells: 109.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 341 "memory B-cell: 128.8;naive B-cell: 133.0" "Lineage enriched" "Detected in single" 346 "B-cells: 133.0" "Cell line enriched" "Detected in some" 913 "Karpas-707: 122629.0" "Immunoglobulin genes" NA NA "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (1.20e-3)" "unprognostic (5.94e-2)" "unprognostic (3.91e-1)" "unprognostic (2.16e-2)" "prognostic favorable (2.03e-4)" "unprognostic (2.11e-1)" "unprognostic (9.60e-3)" "unprognostic (2.47e-2)" "unprognostic (1.88e-1)" "unprognostic (2.74e-1)" "unprognostic (4.11e-1)" "prognostic unfavorable (1.61e-6)" "unprognostic (2.86e-1)" "unprognostic (2.14e-1)" "unprognostic (1.30e-1)" "unprognostic (9.62e-2)" 5.6 4.7 0.0 27.9 0.0 19.9 15.6 0.0 0.4 5.1 0.0 54.1 88.1 4.4 0.5 8.4 4.3 10.7 1.4 0.0 0.5 2.3 3.5 8.3 40.8 0.3 0.0 2.5 1.7 0.1 0.2 0.0 0.2 4.4 23.1 0.0 70.1 0.6 0.1 0.2 23.1 0.9 0.0 107.7 113.1 0.8 0.1 20.0 5.7 0.0 104.2 19.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 85.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 112.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 122629.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 134.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.7 3.0 0.6 111.2 0.0 47.3 0.3 0.1 0.0 0.0 0.1 0.0 128.8 0.0 0.0 0.1 133.0 0.0 0.2 0.1 0.0 0.1 0.3 0.1 25.5 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 109.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.5 0.0 0.4 3.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 RSPH14 RTDR1 ENSG00000100218 "Radial spoke head 14 homolog" Q9UHP6 22 23059415-23145021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 25.0" "Group enriched" "Detected in many" 6 "Early spermatids: 139.7;Late spermatids: 252.0" "Cancer enhanced" "Detected in some" "renal cancer: 2.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "neutrophil: 7.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 7.7" "Cell line enhanced" "Detected in some" "GAMG: 3.2;RPTEC TERT1: 4.2;U-266/70: 4.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA018420, HPA050425" Approved Uncertain Nucleoli NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Nucleoli "HPA018420: AB_1856496, HPA050425: " "unprognostic (8.81e-2)" "unprognostic (1.57e-2)" "unprognostic (1.15e-3)" "unprognostic (3.80e-3)" "unprognostic (1.97e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (1.22e-2)" "unprognostic (8.31e-2)" "unprognostic (7.28e-2)" "prognostic favorable (4.04e-4)" "unprognostic (5.18e-2)" "unprognostic (4.40e-2)" "unprognostic (3.16e-1)" "unprognostic (7.73e-2)" 0.3 2.0 7.7 0.2 9.4 0.2 0.4 5.9 11.8 1.0 9.4 0.6 0.2 0.8 3.5 0.4 12.4 1.3 0.4 8.3 9.9 7.3 0.4 1.5 0.2 8.6 10.9 3.9 0.9 2.4 3.7 0.1 7.7 0.8 0.2 11.4 0.6 1.7 0.7 1.1 0.3 0.3 7.6 0.5 0.7 25.0 7.2 0.1 1.9 0.1 0.2 0.2 0.4 9.5 0.2 2.5 1.9 2.0 0.0 0.9 0.1 0.0 0.5 0.4 0.4 0.4 0.7 0.5 0.7 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.1 0.1 1.0 0.0 0.2 0.4 0.0 1.2 0.0 0.8 0.0 1.0 0.0 0.3 0.3 0.4 0.0 0.6 0.0 0.1 0.0 2.0 4.2 0.0 2.7 0.9 0.0 0.0 0.1 0.1 0.3 0.5 0.0 1.5 0.5 0.1 0.0 4.9 1.9 1.6 1.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 7.7 0.1 1.8 0.0 0.0 0.6 7.7 9.4 5.9 11.8 8.3 9.9 8.6 10.9 7.7 7.6 7.2 9.5 1.9 0.0 0.0 2.0 0.0 0.0 0.9 0.0 0.0 1.1 0.2 0.5 0.1 1.5 3.7 0.0 4.2 0.0 0.2 0.0 7.9 1.0 139.7 17.8 0.5 0.4 0.0 0.0 3.5 0.2 0.0 0.5 0.0 0.5 0.0 1.2 0.7 0.0 0.1 11.8 2.8 0.1 0.0 0.0 0.0 252.0 2.1 0.3 0.0 0.0 0.0 4.6 0.0 1.0 1.1 0.4 0.0 1.9 0.1 0.2 0.0 17.7 29.2 5.1 0.0 0.8 0.9 29.4 8.3 0.0 0.0 0.0 0.4 2.8 0.1 0.3 GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Horizontal cells: 124.5;Rod photoreceptor cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 18.3;SCLC-21H: 39.0;SH-SY5Y: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" 9.2 6.6 30.7 2.8 35.9 1.6 8.4 27.4 36.2 5.4 27.8 14.8 1.7 10.1 2.8 5.0 10.2 11.2 2.4 33.6 24.5 2.0 0.5 1.4 1.8 29.6 30.7 8.9 1.6 7.5 24.1 0.3 32.0 8.5 1.6 33.0 1.8 17.2 1.4 1.4 3.2 11.9 27.0 4.7 11.5 4.3 29.0 0.5 1.5 2.1 1.2 8.0 3.6 35.7 0.1 2.0 6.8 14.3 0.0 0.0 0.4 9.2 18.3 8.9 6.0 0.1 0.1 17.7 0.6 0.8 12.2 0.3 8.4 0.3 6.4 2.2 7.0 1.1 10.2 13.1 0.6 0.0 1.4 0.0 0.3 0.2 0.5 2.2 0.2 1.0 0.2 5.4 0.2 6.4 0.1 0.1 4.1 0.5 5.5 0.1 6.8 2.7 0.1 0.1 39.0 24.0 2.0 4.4 1.9 0.8 1.9 0.2 0.0 7.2 8.2 2.0 0.2 6.6 12.0 9.2 3.7 0.6 2.8 0.9 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.0 2.0 30.7 35.9 27.4 36.2 33.6 24.5 29.6 30.7 32.0 27.0 29.0 35.7 32.1 3.2 0.0 4.9 0.7 0.3 0.3 0.4 0.0 12.6 0.8 1.7 1.6 7.2 0.7 3.7 8.4 0.0 0.7 0.3 0.0 2.0 1.5 1.6 0.5 5.0 4.8 2.7 11.0 1.6 0.0 1.1 1.5 0.4 0.0 2.1 2.2 0.4 0.1 124.5 11.0 0.3 2.0 0.0 1.7 2.1 4.1 18.6 1.8 1.0 1.2 19.3 1.0 2.0 16.5 0.7 0.0 4.1 0.1 0.3 0.1 0.9 1.3 37.7 0.0 9.0 2.1 2.0 4.2 0.0 0.4 0.0 0.6 0.9 0.2 0.1 RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145326-23164350 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 41.2;Late spermatids: 24.5;Respiratory ciliated cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 11.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 11.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.5;U-266/84: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA059631: " "unprognostic (2.74e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (6.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-3)" "unprognostic (5.56e-3)" "prognostic favorable (4.55e-4)" "unprognostic (7.08e-2)" "unprognostic (7.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.08e-1)" 2.0 5.1 8.8 1.3 8.7 0.7 2.6 3.8 8.4 5.1 21.7 3.2 0.7 4.8 4.4 2.1 32.8 5.3 1.4 9.9 9.1 9.1 0.4 4.8 1.1 9.4 11.2 6.2 3.4 5.6 17.1 2.9 6.9 3.9 1.1 2.0 3.3 6.6 0.6 1.8 1.2 3.8 7.9 1.6 2.1 6.7 10.4 0.3 17.6 0.4 1.3 2.5 2.1 5.1 8.1 9.4 7.1 10.7 1.6 3.4 2.8 4.5 9.1 9.8 3.7 0.6 0.0 0.0 4.8 6.0 5.4 10.0 0.3 5.2 3.1 0.0 4.3 0.1 0.4 0.9 4.1 0.0 1.2 4.3 1.9 9.1 1.8 6.4 1.4 0.0 0.4 8.1 0.4 6.4 0.1 0.1 0.9 5.3 2.5 0.0 0.0 25.5 12.7 1.5 17.3 7.5 0.4 3.9 2.2 0.5 0.0 0.9 0.8 1.3 2.9 3.4 6.5 17.3 26.2 0.1 8.8 0.0 5.8 0.3 0.6 0.0 0.5 0.2 0.3 0.8 0.1 0.2 0.2 0.2 0.3 0.3 11.0 1.6 0.3 0.0 0.0 0.3 8.8 8.7 3.8 8.4 9.9 9.1 9.4 11.2 6.9 7.9 10.4 5.1 0.6 0.0 3.2 3.6 1.4 0.5 0.8 4.2 0.0 0.7 1.8 2.8 0.8 4.3 7.0 1.8 6.2 6.0 0.3 0.0 5.9 3.5 10.6 41.2 2.9 0.7 6.7 0.0 2.9 0.2 0.4 2.0 1.5 2.6 1.3 2.4 1.1 0.1 0.4 1.7 1.7 0.7 6.1 0.8 0.3 24.5 3.4 0.3 1.8 1.0 0.5 3.6 1.0 1.5 1.0 0.2 0.2 3.0 0.3 0.4 0.0 9.6 69.6 0.7 0.0 1.0 2.0 3.6 1.6 0.5 0.1 2.9 0.4 4.5 0.3 0.4 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 IGLL1 "14.1, CD179B, IGL5, IGLL, IGVPB" ENSG00000128322 "Immunoglobulin lambda like polypeptide 1" P15814 22 23573125-23580302 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 70.0;testis: 25.2" "Group enriched" "Detected in some" 6 "Early spermatids: 78.0;Late spermatids: 140.7;Melanocytes: 119.2" "Group enriched" "Detected in some" 5 "endometrial cancer: 0.5;lung cancer: 0.5;stomach cancer: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "memory B-cell: 12.0;naive B-cell: 14.8" "Lineage enriched" "Detected in many" 11 "B-cells: 14.8" "Cell line enriched" "Detected in some" 32 "REH: 787.7" "HPA051134, HPA071406" Enhanced Approved "Endoplasmic reticulum" "Secreted to blood" NA NA 48000000000 "Cluster 24: B-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum" "HPA051134: AB_2681356, HPA071406: AB_2686393" "unprognostic (6.21e-2)" "unprognostic (5.12e-2)" "unprognostic (7.31e-2)" "unprognostic (4.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.91e-6)" "unprognostic (1.08e-1)" "unprognostic (5.27e-2)" "unprognostic (6.17e-3)" "unprognostic (5.89e-2)" "unprognostic (9.07e-2)" "unprognostic (1.99e-4)" "unprognostic (2.35e-2)" "unprognostic (5.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.3 0.3 0.3 70.0 0.0 0.3 0.4 0.0 0.4 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.1 1.4 0.3 0.2 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.4 0.2 25.2 0.2 10.1 0.0 0.0 1.9 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 14.3 2.6 0.0 0.0 0.0 787.7 0.3 17.3 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.1 6.2 0.0 0.0 0.3 0.3 0.0 0.6 0.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.8 0.3 0.3 0.3 0.4 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.4 0.0 0.0 0.0 0.8 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 3.9 0.0 78.0 0.2 0.3 0.3 0.0 10.5 0.3 0.0 0.4 0.6 0.0 0.5 0.0 0.2 0.7 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 140.7 1.2 0.4 119.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.0 6.2 0.0 0.0 0.0 1.5 0.3 17.1 0.6 0.0 0.3 0.0 17.9 0.1 0.0 0.2 DRICH1 C22orf43 ENSG00000189269 "Aspartate rich 1" Q6PGQ1 22 23608452-23632321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 17.0;testis: 46.4" "Group enriched" "Detected in some" 44 "Early spermatids: 405.5;Late spermatids: 589.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "CACO-2: 11.1" HPA020446 Approved Nucleoplasm,Nucleoli No No "Cluster 68: Epididymis - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli" "HPA020446: AB_1853151" "unprognostic (7.48e-3)" "unprognostic (3.91e-2)" "unprognostic (2.02e-2)" "unprognostic (6.22e-4)" "unprognostic (6.46e-2)" "unprognostic (8.35e-4)" "unprognostic (2.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.06e-2)" "unprognostic (2.65e-2)" "unprognostic (5.73e-4)" "unprognostic (3.05e-1)" "unprognostic (1.92e-1)" "unprognostic (8.65e-2)" "unprognostic (8.68e-3)" "unprognostic (7.70e-4)" "unprognostic (1.08e-3)" 0.8 1.4 1.3 1.1 1.5 3.7 2.2 3.0 1.9 1.0 2.4 1.3 1.1 3.3 17.0 0.6 1.7 1.8 0.4 0.9 1.1 2.6 0.7 1.3 2.3 1.1 1.2 3.0 2.4 9.2 1.4 0.8 1.1 1.4 1.3 3.9 1.5 2.0 0.2 3.3 1.1 1.5 0.7 2.0 0.8 46.4 1.1 1.4 1.7 0.0 0.8 0.6 0.7 1.0 0.5 0.6 1.5 0.4 1.8 0.4 1.3 0.0 0.0 0.0 0.0 11.1 0.4 0.7 0.1 0.4 0.3 1.1 2.1 0.1 0.3 0.1 1.0 0.4 1.1 0.5 0.6 0.2 1.6 0.8 0.9 0.3 0.0 0.6 0.3 0.3 0.9 0.2 0.1 0.5 0.2 0.5 0.1 0.5 0.6 1.2 0.0 0.0 0.3 1.2 0.6 0.5 0.0 0.9 0.7 0.3 0.2 0.0 0.3 0.0 1.8 1.7 0.2 0.6 1.1 0.1 1.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 3.0 1.9 0.9 1.1 1.1 1.2 1.1 0.7 1.1 1.0 0.1 0.0 0.0 4.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.8 0.0 0.1 0.3 0.1 0.0 0.1 405.5 0.4 0.0 0.3 1.8 0.0 9.1 0.0 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 11.3 0.4 0.0 0.0 0.0 589.5 4.1 0.2 0.0 3.7 0.0 0.0 0.0 1.5 1.4 0.1 1.2 1.5 0.0 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.0 4.4 2.2 0.0 0.0 0.1 0.1 0.1 0.2 0.0 RGL4 Rgr ENSG00000159496 "Ral guanine nucleotide dissociation stimulator like 4" Q8IZJ4 22 23688136-23699176 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "bone marrow: 164.4" "Group enriched" "Detected in some" 4 "dendritic cells: 23.8;Early spermatids: 18.1;NK-cells: 52.5;T-cells: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 393.6;neutrophil: 516.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 516.3" "Group enriched" "Detected in many" 5 "MOLT-4: 26.3;U-937: 61.0" HPA035979 Uncertain Approved Centrosome "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA035979: AB_10673227" "unprognostic (1.48e-4)" "unprognostic (2.75e-4)" "unprognostic (4.44e-2)" "unprognostic (1.11e-4)" "unprognostic (3.10e-1)" "unprognostic (2.93e-4)" "unprognostic (4.92e-2)" "unprognostic (2.06e-2)" "unprognostic (2.78e-1)" "unprognostic (3.11e-1)" "unprognostic (4.25e-2)" "unprognostic (3.80e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (5.13e-2)" "unprognostic (1.26e-1)" "unprognostic (1.07e-3)" 3.8 3.1 0.1 7.6 0.2 164.4 0.5 2.0 0.8 0.3 0.3 1.2 4.1 3.1 0.0 1.9 0.9 4.6 2.8 0.2 0.0 1.5 1.3 4.8 11.5 0.6 0.1 3.9 3.4 0.1 0.5 1.7 1.0 1.4 1.1 10.6 4.6 0.2 3.0 5.6 4.1 0.6 0.1 19.8 2.4 3.8 0.1 8.4 3.1 0.9 8.1 3.8 0.5 1.1 1.6 0.5 5.8 2.5 0.0 0.0 2.5 1.8 0.0 0.0 0.0 1.3 1.1 1.9 0.4 0.0 1.0 2.8 0.0 0.0 0.0 2.0 3.6 0.9 2.5 0.3 0.0 3.4 3.8 0.0 0.0 0.0 0.0 2.9 0.0 2.0 2.1 3.0 0.0 1.0 26.3 3.6 0.4 0.6 0.8 9.3 2.0 1.4 0.0 1.7 1.8 2.7 1.7 3.7 0.6 3.1 1.2 2.0 2.5 3.2 1.9 2.2 1.1 5.3 0.8 1.3 1.9 61.0 1.6 98.0 2.9 393.6 57.4 20.8 59.6 6.5 74.1 66.2 5.4 5.2 104.6 93.8 516.3 35.2 84.6 0.7 114.2 37.4 0.1 0.2 2.0 0.8 0.2 0.0 0.6 0.1 1.0 0.1 0.1 1.1 0.7 0.0 4.4 0.3 5.9 0.9 0.0 0.0 0.0 0.5 0.4 0.5 0.5 1.5 1.3 0.0 2.1 0.0 23.8 0.0 0.0 2.4 18.1 0.1 0.3 0.3 0.0 8.8 0.4 1.7 0.1 0.6 2.6 0.2 1.3 0.1 0.4 0.3 0.1 1.7 0.5 0.0 0.0 1.6 0.7 2.0 0.0 3.5 1.8 0.0 2.5 0.0 52.5 0.5 0.4 2.2 0.0 0.0 3.4 0.0 0.0 0.3 0.0 2.8 0.0 0.3 0.5 5.9 0.0 0.0 0.3 0.0 51.8 0.1 0.1 0.1 ZNF70 "Cos17, MGC48959" ENSG00000187792 "Zinc finger protein 70" Q9UC06 22 23738682-23751112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018821 Uncertain Approved Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" Cytosol "HPA018821: AB_1859423" "unprognostic (3.17e-2)" "unprognostic (2.31e-1)" "unprognostic (2.78e-1)" "unprognostic (8.49e-3)" "unprognostic (1.08e-1)" "unprognostic (2.80e-2)" "unprognostic (6.07e-3)" "unprognostic (2.18e-3)" "unprognostic (9.93e-2)" "unprognostic (6.20e-2)" "unprognostic (1.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.95e-2)" "unprognostic (6.72e-2)" "unprognostic (2.40e-1)" "unprognostic (4.36e-2)" "unprognostic (5.69e-2)" 1.4 1.2 1.0 1.3 1.4 1.6 1.3 2.8 1.1 1.9 2.2 1.4 0.8 1.9 2.3 0.8 1.9 1.1 1.6 0.9 1.0 1.0 0.7 1.2 1.4 2.0 1.4 3.9 1.8 2.1 1.6 1.2 1.1 1.5 1.2 3.0 2.0 1.5 2.6 1.1 1.2 1.6 0.8 1.4 1.3 1.2 1.6 1.2 1.8 2.1 1.6 1.4 1.3 2.5 1.2 1.5 2.9 3.0 4.2 2.0 0.9 1.1 2.2 2.5 3.5 1.5 0.8 1.7 0.7 2.4 1.6 1.3 2.0 1.5 3.1 1.1 1.8 3.3 3.0 1.3 2.5 3.0 2.7 2.0 0.9 3.3 2.7 3.2 2.0 1.3 1.2 2.4 1.8 1.6 1.7 1.4 0.7 1.1 0.6 7.2 2.8 0.4 0.9 1.6 1.6 2.0 1.6 2.0 1.2 2.0 1.0 1.4 2.6 2.7 3.4 1.8 1.2 2.4 0.4 1.5 2.4 1.3 2.4 1.5 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.3 0.2 0.3 0.8 0.5 0.2 0.4 0.1 0.1 1.0 1.4 2.8 1.1 0.9 1.0 2.0 1.4 1.1 0.8 1.6 2.5 1.2 0.0 2.8 0.7 1.0 0.4 1.1 0.0 1.2 3.8 1.1 1.4 2.6 2.8 1.8 3.7 10.4 0.4 2.1 0.3 0.0 1.1 1.4 1.6 3.9 1.7 1.2 0.8 0.8 1.1 0.6 3.2 0.5 1.0 1.3 3.8 4.2 0.5 0.8 6.7 1.2 0.6 0.0 1.6 0.6 3.3 6.2 1.0 0.0 0.0 0.8 2.1 0.0 0.0 1.6 0.4 0.0 4.1 1.5 0.7 0.8 0.9 3.6 4.0 6.6 5.4 2.7 2.7 2.5 1.0 0.0 0.3 1.2 2.8 0.7 0.9 VPREB3 8HS20 ENSG00000128218 "V-set pre-B cell surrogate light chain 3" Q9UKI3 22 23752743-23754425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;intestine: 72.5;lymphoid tissue: 118.5" "Cell type enriched" "Detected in some" 12 "B-cells: 287.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 709 "memory B-cell: 753.3;naive B-cell: 803.7" "Lineage enriched" "Detected in many" 732 "B-cells: 803.7" "Group enriched" "Detected in some" 46 "Daudi: 263.3;REH: 309.9;U-698: 85.2" "Low region specificity" "Detected in single" HPA003041 Supported "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA003041: AB_1080577" "unprognostic (2.06e-3)" "unprognostic (4.75e-3)" "unprognostic (2.35e-1)" "unprognostic (2.39e-2)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (4.79e-2)" "unprognostic (6.63e-3)" "unprognostic (9.15e-2)" "unprognostic (1.38e-2)" "unprognostic (4.93e-2)" "unprognostic (4.84e-2)" "unprognostic (8.44e-2)" "unprognostic (4.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.87e-1)" "unprognostic (4.12e-1)" 1.7 21.1 2.0 41.3 2.0 25.8 0.4 2.6 3.8 0.3 2.6 3.9 1.7 1.1 51.5 1.2 0.3 2.7 1.1 1.7 2.0 1.6 1.9 0.8 112.4 2.1 2.1 0.1 0.5 0.6 2.5 0.2 2.1 1.6 3.7 2.2 2.5 0.3 1.6 0.6 72.5 0.3 1.9 60.3 6.1 0.6 2.9 7.9 1.7 0.5 118.5 6.2 0.3 1.8 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.6 263.3 0.3 0.2 0.0 0.1 0.5 0.2 0.1 0.6 2.8 0.1 0.0 0.2 0.2 0.3 0.1 1.1 0.7 0.0 0.0 0.0 0.0 0.4 0.4 1.1 0.0 1.3 0.5 1.0 0.3 0.3 1.1 309.9 0.5 4.7 0.1 0.1 0.7 1.0 0.3 0.7 3.5 0.2 0.6 0.4 1.2 0.0 0.5 0.9 0.0 1.3 0.3 85.2 0.0 0.5 0.3 0.9 0.7 0.6 0.4 0.3 0.4 753.3 0.4 0.5 0.7 803.7 0.5 0.5 1.0 0.4 0.7 0.6 1.0 17.5 2.0 2.0 2.6 3.8 1.7 2.0 2.1 2.1 2.1 1.9 2.9 1.8 0.1 0.0 0.5 0.3 287.8 0.4 0.8 0.6 0.6 4.5 0.3 0.5 0.9 1.5 0.8 0.0 2.1 0.0 5.4 1.1 1.9 0.1 0.3 0.1 0.8 0.1 5.4 2.7 0.2 0.0 0.0 1.5 1.5 0.3 0.0 0.7 1.1 1.0 0.3 0.0 0.2 0.6 2.0 0.3 0.8 0.2 0.0 1.2 5.4 0.0 0.7 0.8 2.1 0.5 0.1 0.1 0.3 0.0 22.6 0.2 1.5 2.4 0.0 2.1 0.0 0.5 0.4 0.1 0.2 0.4 0.1 0.0 3.5 0.1 0.7 0.3 C22orf15 "FLJ36561, N27C7-3" ENSG00000169314 "Chromosome 22 open reading frame 15" Q8WYQ4 22 23762990-23765863 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "fallopian tube: 18.3" "Cell type enriched" "Detected in some" 5 "Respiratory ciliated cells: 198.2" "Cancer enriched" "Detected in single" 4 "endometrial cancer: 1.7" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 1.2;BJ: 1.2;BJ hTERT+: 2.3;hTERT-RPE1: 3.2;MOLT-4: 1.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Secreted in female reproductive system" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (2.37e-2)" "unprognostic (3.28e-3)" "unprognostic (1.28e-1)" "prognostic favorable (8.53e-5)" "unprognostic (1.86e-2)" "unprognostic (2.07e-2)" "unprognostic (4.38e-2)" "unprognostic (6.14e-2)" "unprognostic (3.60e-2)" "unprognostic (7.70e-2)" "unprognostic (4.58e-2)" "unprognostic (2.60e-1)" "unprognostic (9.79e-2)" "unprognostic (2.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.28e-2)" "unprognostic (3.08e-3)" 0.1 0.0 0.3 0.0 0.2 0.3 0.1 0.2 0.2 0.4 0.5 0.2 0.0 0.2 0.0 0.0 18.3 0.2 0.0 0.3 0.6 0.1 0.0 1.8 0.1 1.1 1.6 0.5 0.0 0.0 1.0 0.2 1.1 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.2 0.1 2.8 0.3 1.0 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.1 1.2 0.0 0.0 0.0 0.0 1.2 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 3.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.3 0.2 0.1 0.1 0.5 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.2 0.2 0.2 0.3 0.6 1.1 1.6 1.1 0.8 0.3 0.2 0.0 0.0 1.8 1.3 0.0 0.1 0.0 9.1 0.0 0.5 0.0 0.5 0.1 0.0 15.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 6.0 35.8 0.2 0.2 0.0 0.4 2.3 0.0 0.0 1.4 0.0 0.3 2.5 0.1 0.7 0.1 0.0 0.0 2.0 0.0 16.2 0.3 0.4 3.5 0.0 0.3 0.0 1.0 0.1 0.2 0.0 0.5 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 198.2 1.9 0.0 0.1 3.5 10.9 4.2 0.0 0.3 0.0 1.0 0.5 0.0 0.1 CHCHD10 "C22orf16, MIX17A, N27C7-4" ENSG00000250479 "Coiled-coil-helix-coiled-coil-helix domain containing 10" Q8WYQ3 22 23765834-23767972 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1622.6;skeletal muscle: 1220.9" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1264.7;Distal tubular cells: 2498.5;Hepatocytes: 1879.9;Proximal enterocytes: 1501.3;Proximal tubular cells: 1437.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003440 Enhanced Supported Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003440: AB_1078348" "unprognostic (3.88e-2)" "unprognostic (2.36e-3)" "unprognostic (8.90e-2)" "unprognostic (9.80e-2)" "unprognostic (7.68e-2)" "unprognostic (5.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.85e-1)" "unprognostic (2.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (5.13e-2)" "prognostic favorable (2.15e-7)" "unprognostic (5.19e-3)" "unprognostic (2.06e-1)" "unprognostic (5.68e-3)" "unprognostic (2.62e-3)" 216.5 136.5 181.6 30.3 188.3 12.5 144.5 183.0 248.9 77.3 262.6 261.2 92.6 35.5 32.4 147.3 43.1 10.9 1622.6 176.6 190.5 409.5 789.7 56.9 28.6 182.2 182.2 29.0 118.0 220.0 112.3 11.9 187.6 106.4 76.2 63.1 148.3 50.5 1220.9 71.8 159.0 17.9 169.5 100.3 160.2 27.8 204.8 14.0 224.7 660.7 34.5 110.2 89.1 179.3 33.1 66.4 19.7 85.9 42.1 27.7 41.9 11.9 22.8 23.5 28.4 124.1 35.1 113.5 30.7 41.2 12.9 99.8 109.2 34.1 20.5 35.9 140.6 22.5 48.8 117.1 73.8 63.6 108.2 53.3 91.9 35.6 9.3 4.9 29.0 17.2 47.7 48.0 20.6 121.8 21.8 48.2 16.9 194.9 183.5 90.0 4.0 209.0 112.7 55.3 41.3 23.8 13.9 145.7 149.7 36.6 54.9 47.0 15.3 1.0 1.1 18.3 0.2 28.8 11.1 62.5 20.5 54.9 11.2 0.2 4.1 11.2 3.0 9.1 1.9 11.7 3.2 4.0 1.8 10.6 4.9 3.5 0.0 0.8 8.2 7.3 4.3 1.2 181.6 188.3 183.0 248.9 176.6 190.5 182.2 182.2 187.6 169.5 204.8 179.3 88.7 12.8 10.5 36.2 294.8 48.2 415.4 28.2 144.5 136.2 156.9 238.2 503.8 268.8 20.5 419.3 114.7 42.5 104.7 1264.7 2498.5 88.1 27.0 76.6 229.8 47.4 310.5 74.3 38.5 54.5 255.7 67.8 300.7 94.3 84.0 171.9 78.1 1879.9 647.5 99.3 37.6 860.9 26.4 262.1 127.5 18.0 48.7 243.1 373.5 15.9 107.8 188.5 25.7 17.1 17.4 45.9 890.1 29.3 297.3 192.4 1501.3 1437.4 10.0 287.8 124.9 254.0 200.4 32.3 43.4 459.3 43.9 105.2 123.0 216.0 952.4 470.1 MMP11 STMY3 ENSG00000099953 "Matrix metallopeptidase 11" P24347 22 23768226-23784316 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 64.8;endometrium 1: 142.8;placenta: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 84.9;Extravillous trophoblasts: 37.6;Granulosa cells: 61.9;Smooth muscle cells: 35.8" "Cancer enhanced" "Detected in all" "pancreatic cancer: 119.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 4.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 4.4" "Cell line enhanced" "Detected in many" "AN3-CA: 38.4;hTERT-RPE1: 19.7;REH: 16.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002593, HPA055204, HPA068864" Approved Approved "Golgi apparatus,Cytosol" "Secreted to extracellular matrix" NA NA 640000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Cytosol "CAB002593: , HPA055204: , HPA068864: AB_2686051" "unprognostic (1.06e-1)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.84e-3)" "unprognostic (2.77e-2)" "unprognostic (6.73e-2)" "unprognostic (2.14e-2)" "unprognostic (5.15e-1)" "unprognostic (2.73e-2)" "unprognostic (2.20e-1)" "unprognostic (1.89e-3)" "unprognostic (7.04e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (8.05e-2)" "unprognostic (6.78e-2)" "unprognostic (1.10e-1)" "unprognostic (1.68e-2)" 3.3 1.6 0.4 1.4 0.3 0.5 2.2 0.3 1.2 64.8 0.3 3.9 6.8 142.8 0.1 1.0 5.7 6.8 7.2 0.3 0.4 2.5 0.6 1.4 3.9 0.4 0.4 12.5 1.3 3.3 0.5 39.6 0.4 1.9 3.5 0.0 5.3 1.5 0.9 3.8 6.0 9.4 0.4 1.4 2.6 6.7 0.4 3.1 1.3 0.9 1.7 2.9 3.6 0.4 0.3 0.0 4.8 38.4 5.7 8.3 0.1 0.6 10.4 1.3 0.8 0.4 1.3 1.3 5.1 2.8 1.8 0.2 2.2 0.0 0.4 0.0 0.8 0.0 0.0 2.2 4.2 0.0 0.0 5.4 0.9 1.1 0.1 19.7 6.0 0.4 0.6 0.0 1.4 0.3 0.1 0.1 1.4 1.2 0.2 16.6 0.0 0.4 0.7 0.0 6.0 10.3 3.9 0.6 0.0 5.9 3.6 0.0 2.7 0.6 0.0 1.6 0.1 0.1 0.2 5.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.1 0.4 0.3 0.3 1.2 0.3 0.4 0.4 0.4 0.4 0.4 0.4 0.4 1.2 0.0 2.5 0.3 3.4 1.0 0.8 0.8 0.6 0.4 1.9 0.5 6.1 1.5 0.1 0.0 0.0 0.7 1.8 0.4 1.9 8.6 10.3 4.4 84.9 0.9 1.8 0.0 0.2 0.7 37.6 8.4 1.5 4.1 1.3 61.9 1.1 0.0 0.8 0.0 0.4 1.3 2.0 0.0 1.1 10.5 0.6 1.0 1.8 1.0 0.0 0.3 0.0 0.0 0.2 1.4 0.2 0.4 0.2 0.5 0.1 2.2 0.8 0.5 0.0 2.7 35.8 3.1 5.5 0.5 0.6 18.6 2.0 5.7 1.0 0.3 SMARCB1 "BAF47, hSNFS, Ini1, PPP1R144, RDT, Sfh1p, SNF5, SNF5L1, Snr1" ENSG00000099956 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1" Q12824 22 23786931-23838009 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009196, HPA018248, HPA019127" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center" "CAB009196: AB_2191983, HPA018248: AB_1851162, HPA019127: AB_1851165" "unprognostic (2.15e-1)" "unprognostic (5.62e-2)" "unprognostic (6.60e-3)" "unprognostic (1.63e-2)" "unprognostic (4.01e-3)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.52e-4)" "unprognostic (4.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-2)" "unprognostic (2.10e-2)" "unprognostic (4.43e-3)" "prognostic favorable (1.14e-6)" "unprognostic (1.24e-1)" "unprognostic (4.58e-2)" "unprognostic (4.57e-2)" "unprognostic (7.04e-2)" 35.9 46.4 2.3 6.9 2.5 3.3 40.3 4.1 10.0 51.5 2.7 40.9 8.1 51.4 0.4 51.0 40.4 2.2 44.0 2.3 2.3 47.0 36.9 32.3 5.8 4.3 2.7 63.1 43.9 1.2 48.0 1.2 2.7 36.6 1.1 25.3 44.1 0.6 48.1 50.1 51.7 0.6 2.2 51.7 40.4 68.3 2.3 3.5 41.3 1.8 1.5 37.5 40.9 2.9 2.4 1.6 28.2 2.6 2.7 0.7 5.8 9.2 2.7 2.7 4.3 3.4 2.6 24.2 7.9 1.2 2.9 4.4 6.9 4.6 4.5 4.1 10.5 20.1 3.2 2.1 3.0 21.7 5.6 1.6 3.4 3.2 6.9 1.4 1.4 3.0 5.6 12.9 1.7 6.1 17.6 5.0 8.6 7.2 5.7 11.0 23.1 10.8 2.3 4.5 13.4 10.1 2.2 0.6 17.9 14.8 2.2 3.3 2.2 2.4 9.8 3.8 2.7 13.8 14.3 17.7 1.8 11.3 6.8 7.1 12.8 6.4 4.4 13.4 6.4 24.4 5.5 5.7 12.0 9.2 4.5 3.0 1.1 9.8 16.8 13.3 10.4 8.1 2.3 2.5 4.1 10.0 2.3 2.3 4.3 2.7 2.7 2.2 2.3 2.9 33.6 6.4 8.6 17.0 120.2 50.2 73.3 85.1 51.2 55.4 42.9 49.1 6.1 47.1 37.4 47.8 20.9 120.6 61.8 36.6 84.1 94.6 42.6 40.9 54.9 37.4 71.8 57.8 14.1 77.1 228.1 46.2 41.8 41.1 34.8 112.2 41.0 20.3 76.1 67.3 18.4 54.6 99.7 23.0 41.7 18.9 35.8 36.5 56.9 15.9 51.2 92.4 45.3 17.1 18.1 74.7 53.1 32.0 139.6 74.4 41.9 86.4 28.5 49.6 19.7 47.7 62.8 138.9 163.3 64.5 53.0 160.1 42.0 96.8 65.4 65.1 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 SLC2A11 "GLUT10, GLUT11" ENSG00000133460 "Solute carrier family 2 member 11" Q9BYW1 22 23856703-23886309 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 298.2;Rod photoreceptor cells: 188.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-BR-3: 9.2" "Low region specificity" "Detected in all" "HPA042960, HPA071184" Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions" Nucleoplasm "HPA042960: AB_2678241, HPA071184: AB_2686355" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (3.69e-2)" "unprognostic (6.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.32e-1)" "unprognostic (4.24e-2)" "unprognostic (1.60e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "prognostic favorable (3.83e-4)" "unprognostic (2.32e-1)" "prognostic favorable (5.77e-7)" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (6.29e-2)" 2.3 6.3 3.9 1.7 3.7 1.1 3.3 5.3 4.5 4.8 3.4 5.2 1.2 3.4 3.0 1.6 3.6 1.3 10.2 3.3 4.1 16.5 5.1 2.3 2.7 3.7 3.7 4.9 12.9 6.1 13.2 2.7 4.1 5.1 2.0 19.5 3.9 2.9 6.3 2.3 4.6 1.8 3.0 4.2 4.4 3.2 4.1 0.7 7.2 1.9 2.2 4.3 2.2 3.5 2.2 1.0 1.2 5.7 1.2 2.5 0.6 1.3 1.6 1.4 0.9 1.3 1.5 2.7 0.7 1.7 1.2 1.7 2.4 0.8 0.7 2.0 2.2 1.3 2.5 2.0 1.8 1.3 1.4 1.0 2.4 2.0 1.7 6.3 0.5 2.1 0.5 6.4 0.7 2.2 0.3 0.5 2.1 1.3 1.6 3.7 0.2 3.1 4.3 0.6 3.2 1.8 0.6 9.2 2.2 1.5 4.8 0.7 0.4 0.5 0.9 0.5 0.6 5.5 1.6 2.6 1.1 0.9 1.4 0.4 0.1 0.4 0.2 0.3 0.1 0.6 0.2 0.2 0.0 0.5 0.4 0.2 0.2 0.3 0.2 1.4 0.0 0.1 3.9 3.7 5.3 4.5 3.3 4.1 3.7 3.7 4.1 3.0 4.1 3.5 2.9 19.2 15.0 14.4 23.4 3.2 9.3 4.4 8.6 56.0 15.0 13.5 31.2 7.2 5.6 25.8 298.2 9.8 15.5 5.7 13.7 4.9 8.4 4.8 8.2 4.4 10.8 5.0 21.6 5.6 9.8 8.3 5.1 5.3 2.5 19.5 6.1 7.3 5.8 37.0 30.0 5.8 10.2 4.8 4.6 10.4 9.3 4.3 3.6 4.7 4.2 16.4 10.3 8.0 14.2 2.7 2.7 9.8 15.2 7.3 3.7 24.7 6.3 188.8 0.0 11.8 7.5 4.2 5.7 5.3 3.1 20.0 8.3 28.3 7.5 6.0 AP000350.4 ENSG00000251357 "Novel protein" 22 23862188-23895223 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 78.1;Club cells: 43.0;Fibroblasts: 25.6;granulocytes: 54.2;Melanocytes: 33.8;Respiratory ciliated cells: 44.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.1;SK-MEL-30: 1.6;THP-1: 1.5" HPA042960 Uncertain NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "HPA042960: AB_2678241" 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.2 0.1 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.5 0.4 0.6 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.1 1.0 0.0 0.5 1.6 0.1 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.8 0.0 0.4 0.3 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 78.1 0.0 0.2 16.4 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 43.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 54.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.2 0.0 15.5 0.0 0.0 3.3 33.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 44.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 14.5 0.0 9.0 0.0 0.5 0.0 MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 2032.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 4974.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" No No 13800000 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Nucleoplasm "CAB005284: AB_648587, HPA003868: AB_1079290" "unprognostic (1.68e-1)" "unprognostic (7.79e-3)" "unprognostic (2.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-2)" "unprognostic (9.48e-2)" "unprognostic (1.22e-3)" "unprognostic (2.17e-2)" "unprognostic (1.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.28e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.55e-1)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" 233.3 467.9 195.8 119.5 200.0 146.0 223.3 209.3 450.0 235.0 204.3 194.3 98.9 205.3 49.8 514.2 219.4 20.9 290.8 245.2 289.7 530.3 484.6 208.2 61.5 225.2 224.7 223.7 255.7 127.8 368.0 100.4 217.2 318.7 35.2 23.8 233.6 132.8 99.3 302.5 171.7 43.4 250.8 204.5 230.7 113.5 204.2 65.0 274.0 19.5 46.2 255.8 316.7 369.4 1698.3 605.3 122.2 499.0 58.9 111.3 590.7 581.2 154.7 298.9 382.1 526.4 364.4 761.3 499.8 83.1 115.2 788.1 155.0 546.8 51.5 642.2 4974.4 286.2 534.6 1126.5 225.3 1077.2 758.6 230.9 354.9 173.8 103.5 248.8 241.3 589.4 466.9 540.1 122.2 1476.0 827.0 2345.5 532.8 488.6 2365.8 1040.4 127.9 2398.8 294.7 179.6 1080.9 1290.4 380.3 531.9 1374.7 37.6 671.2 442.6 424.7 232.5 1227.9 127.3 9.9 1647.2 732.5 1020.9 967.5 484.6 477.9 484.2 543.5 443.5 872.4 579.5 1250.8 1527.9 1221.7 983.3 796.9 1378.9 1040.4 928.4 166.8 1158.9 383.3 977.1 1258.3 1803.3 195.8 200.0 209.3 450.0 245.2 289.7 225.2 224.7 217.2 250.8 204.2 369.4 161.2 157.0 199.4 21.5 433.4 672.2 295.5 1134.8 1027.2 28.3 856.0 778.2 0.3 479.0 489.1 693.4 2.1 462.7 171.3 317.9 1649.4 859.0 190.5 733.7 485.3 248.5 348.9 455.7 17.1 377.7 885.0 336.2 606.5 844.3 180.3 192.2 261.6 885.2 278.8 21.9 24.1 432.5 697.8 207.7 505.2 153.9 336.1 232.6 773.7 19.7 217.0 59.5 155.5 17.6 52.8 649.9 360.4 302.8 1337.1 269.8 476.8 2032.7 404.6 33.2 138.1 338.1 349.7 21.3 124.2 1511.3 758.8 686.0 386.3 227.6 473.0 256.1 GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B" P0CG30 22 23957414-23961195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 81.8;breast: 307.9" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Hepatocytes: 27.6;Muller glia cells: 20.9;Peritubular cells: 28.6;Skeletal myocytes: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 57.0;HHSteC: 81.9;SK-MEL-30: 60.3;T-47d: 64.8" HPA000750 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 82: Adipose tissue - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol Nucleoplasm "HPA000750: AB_1849804" "prognostic favorable (5.06e-4)" "unprognostic (5.14e-2)" "unprognostic (1.90e-1)" "unprognostic (4.51e-2)" "unprognostic (7.13e-2)" "unprognostic (8.41e-3)" "unprognostic (2.58e-1)" "unprognostic (7.99e-2)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (1.76e-2)" "unprognostic (4.11e-1)" "unprognostic (1.18e-2)" "unprognostic (2.04e-1)" "unprognostic (1.07e-1)" "unprognostic (1.48e-2)" "unprognostic (2.19e-3)" 12.3 81.8 21.6 4.3 21.5 0.0 307.9 21.4 27.0 16.6 19.5 17.2 1.4 15.5 12.0 24.7 16.1 5.5 23.9 20.8 22.7 15.2 39.5 18.5 1.8 22.2 22.2 22.6 26.1 6.4 26.0 4.4 22.2 40.6 1.9 3.8 12.5 10.4 16.4 47.8 8.3 11.8 21.0 10.2 23.8 5.5 24.3 1.8 18.6 41.0 1.6 12.1 14.0 21.1 17.0 0.8 0.0 57.0 1.0 1.1 2.4 8.0 4.7 11.5 11.9 24.8 0.2 0.0 12.9 20.2 29.7 24.5 0.0 25.5 5.2 0.0 2.2 0.9 33.6 4.0 81.9 0.1 9.1 33.4 4.0 33.2 6.7 32.6 9.6 0.0 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.9 12.5 0.0 42.4 0.1 26.0 0.0 1.1 23.8 8.2 0.2 60.3 0.2 64.8 0.9 32.0 9.9 6.5 1.3 6.4 0.0 0.0 0.1 6.1 0.0 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 21.5 21.4 27.0 20.8 22.7 22.2 22.2 22.2 21.0 24.3 21.1 8.1 3.2 3.6 1.3 0.9 0.0 8.6 0.0 2.8 3.9 9.4 17.9 0.2 7.2 1.3 0.0 0.0 1.6 0.1 0.0 29.4 7.9 0.6 1.3 11.8 7.1 1.2 5.3 2.4 9.1 3.5 7.6 1.1 2.9 1.3 2.2 18.5 27.6 10.5 0.0 2.1 0.4 0.0 3.8 0.0 1.5 9.9 1.5 0.0 0.0 3.2 20.9 0.0 2.0 0.7 4.2 0.0 28.6 0.7 7.9 0.0 5.7 0.0 2.8 6.6 26.7 9.6 0.4 0.7 0.9 0.0 1.8 0.2 0.4 0.1 3.8 DDTL ENSG00000099974 "D-dopachrome tautomerase like" A6NHG4 22 23966888-23972556 "Predicted intracellular proteins" Lyase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 58.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Cardiomyocytes: 11.5;Distal tubular cells: 5.9;Hepatocytes: 6.4;Proximal enterocytes: 7.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 14.9" HPA074115 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "HPA074115: " "unprognostic (6.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.91e-1)" "unprognostic (6.34e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "prognostic favorable (5.98e-4)" "unprognostic (2.65e-2)" "unprognostic (2.26e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-2)" "unprognostic (2.18e-1)" "unprognostic (5.74e-2)" "unprognostic (2.05e-2)" "unprognostic (1.46e-1)" "unprognostic (3.70e-2)" "unprognostic (3.58e-3)" 4.2 5.5 0.1 3.8 0.5 5.6 4.1 1.3 0.5 4.6 0.5 7.3 6.3 3.7 1.3 6.6 4.1 2.4 8.0 0.3 0.1 11.3 58.6 4.1 5.1 0.9 0.4 6.3 15.3 1.3 4.2 2.2 0.8 8.4 1.8 5.1 5.2 0.3 4.1 5.2 8.1 0.4 0.0 7.4 9.5 3.6 0.7 0.2 5.8 3.2 0.1 4.5 5.0 1.8 4.6 3.1 3.5 3.8 0.0 0.3 4.4 2.5 0.0 0.0 0.0 6.9 4.5 7.8 1.6 0.0 3.2 11.6 1.2 0.0 0.0 2.9 14.9 4.4 13.6 6.7 1.2 11.1 4.7 0.0 0.0 0.0 0.0 4.7 0.0 2.6 4.5 5.6 0.0 3.5 1.2 6.4 1.3 3.5 2.6 6.5 3.7 1.0 2.1 6.4 3.8 1.9 3.4 6.4 11.4 4.1 5.2 0.8 0.0 6.6 5.1 2.0 1.8 4.2 1.3 2.2 1.5 5.4 2.4 6.8 1.0 1.8 1.4 1.6 1.6 1.4 1.0 2.1 0.9 1.4 0.7 1.2 0.5 2.3 0.3 1.3 1.1 0.8 0.1 0.5 1.3 0.5 0.3 0.1 0.9 0.4 0.8 0.0 0.7 1.8 0.3 6.4 3.1 0.0 0.6 1.0 1.3 0.1 1.2 0.9 0.9 1.7 11.5 2.8 1.4 0.0 4.2 1.2 0.7 3.0 5.9 1.0 1.6 0.1 0.5 1.3 1.2 0.4 0.3 0.4 1.4 1.7 0.0 0.4 1.3 0.4 2.5 6.4 1.0 0.0 0.4 1.2 0.0 1.2 0.8 0.7 0.6 1.5 0.0 0.0 0.6 0.4 1.0 0.0 0.5 1.2 2.2 1.2 0.7 0.9 7.6 5.1 0.3 0.7 0.0 1.1 1.4 0.2 0.6 1.5 0.9 2.5 1.0 0.0 2.5 0.7 DDT "D-DT, DDCT, MIF-2, MIF2" ENSG00000099977 "D-dopachrome tautomerase" P30046 22 23971365-23979828 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Melanin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 835.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 4869.6;Proximal tubular cells: 1415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 262.9" "HPA049871, HPA074115" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Mitochondria "HPA049871: AB_2680926, HPA074115: " "unprognostic (1.77e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.22e-2)" "unprognostic (8.09e-2)" "unprognostic (4.00e-3)" "unprognostic (2.02e-3)" "unprognostic (6.58e-2)" "unprognostic (4.66e-2)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" "unprognostic (6.06e-3)" "unprognostic (1.12e-1)" "unprognostic (7.34e-2)" "unprognostic (3.30e-1)" "unprognostic (3.81e-1)" "unprognostic (2.61e-3)" 125.7 126.7 29.6 15.1 30.6 39.6 99.0 33.1 38.0 69.6 28.7 128.5 44.2 62.6 16.2 119.1 67.3 6.3 167.0 28.9 32.2 218.2 835.9 69.2 13.7 30.7 29.6 83.0 260.9 24.3 47.7 10.7 30.7 109.0 24.2 12.8 82.7 15.7 129.3 89.8 120.7 8.6 30.7 66.3 176.2 39.2 32.9 12.3 80.1 15.7 11.9 86.8 76.4 33.9 107.6 44.8 15.4 34.9 29.0 24.9 92.6 30.4 20.7 26.1 27.1 39.8 30.6 101.9 27.8 16.1 37.7 86.3 38.3 38.1 17.1 43.6 262.9 60.8 58.9 88.3 28.9 136.2 58.8 25.5 28.5 26.3 23.1 27.9 28.7 16.0 56.8 40.2 26.9 53.0 30.1 123.1 46.2 94.4 134.2 65.3 27.0 148.9 46.4 39.2 51.7 49.2 62.8 117.7 95.9 20.6 30.8 42.3 33.1 26.8 59.9 27.8 32.2 122.6 43.9 65.1 53.1 49.7 52.5 63.5 92.9 72.4 46.0 82.8 47.5 75.3 55.3 49.1 87.8 70.7 49.2 48.9 58.3 61.6 79.1 130.4 74.5 78.8 29.6 30.6 33.1 38.0 28.9 32.2 30.7 29.6 30.7 30.7 32.9 33.9 116.9 83.3 86.3 11.1 178.3 138.9 220.5 278.8 176.4 58.4 266.6 379.7 21.3 499.0 153.2 242.8 89.6 202.6 134.1 533.1 718.1 237.2 202.1 150.8 126.4 103.4 259.6 230.2 9.1 375.7 288.2 103.9 163.1 260.3 129.4 97.1 154.9 4869.6 281.0 43.7 11.0 402.8 187.2 240.4 162.2 411.0 117.1 172.2 158.3 9.4 235.8 119.6 135.9 6.0 18.8 233.6 395.1 110.6 166.1 257.5 935.1 1415.8 97.6 100.0 78.9 109.5 127.6 117.9 43.8 280.6 188.0 299.8 140.3 212.5 558.7 291.3 AC253536.7 ENSG00000285762 "Novel protein, AP000351.4-DDT readtrhough" 22 23971378-23980469 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 15.4;Club cells: 4.3;granulocytes: 3.8;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;HaCaT: 1.0;hTERT-RPE1: 2.2;RH-30: 1.2" "HPA049871, HPA074115" Uncertain Approved Mitochondria NA NA "Cluster 23: AN3-CA - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" Mitochondria "HPA049871: AB_2680926, HPA074115: " 0.1 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.0 0.3 0.2 0.0 0.4 0.4 0.1 0.5 0.0 0.4 0.3 0.0 0.0 0.2 0.8 0.0 0.5 0.0 0.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.5 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.9 1.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.3 0.1 0.4 0.4 0.3 0.0 0.3 0.5 0.0 6.4 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 GSTT4 "GSTTP1, HS322B1A" ENSG00000276950 "Glutathione S-transferase theta 4" A0A1W2PR19 22 23998401-24005453 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 24 "testis: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "unprognostic (5.66e-2)" "unprognostic (1.77e-2)" "unprognostic (6.83e-4)" "unprognostic (4.36e-1)" "unprognostic (5.47e-1)" "unprognostic (2.23e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CABIN1 "KIAA0330, PPP3IN" ENSG00000099991 "Calcineurin binding protein 1" Q9Y6J0 22 24011192-24178628 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043296 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA043296: AB_10794657" "unprognostic (8.52e-2)" "unprognostic (3.16e-1)" "unprognostic (2.74e-2)" "prognostic favorable (9.57e-5)" "unprognostic (3.43e-2)" "unprognostic (3.06e-3)" "unprognostic (1.04e-2)" "unprognostic (2.92e-2)" "unprognostic (6.21e-2)" "unprognostic (3.75e-1)" "unprognostic (3.46e-3)" "unprognostic (1.01e-1)" "prognostic favorable (2.94e-4)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-3)" "unprognostic (7.79e-2)" 27.2 28.7 28.9 15.5 29.1 30.9 24.3 33.3 40.9 33.3 32.6 37.0 13.6 32.4 8.7 23.4 35.9 10.1 30.9 28.8 25.6 36.0 28.2 28.5 19.6 28.0 27.5 27.3 28.1 15.6 46.2 8.2 28.1 34.0 8.4 13.3 22.1 14.1 17.4 24.7 33.1 11.0 23.1 37.2 31.9 34.4 29.2 19.5 50.3 7.0 10.0 29.7 27.1 28.9 24.7 17.7 23.6 20.8 20.9 24.1 33.3 20.4 17.5 16.0 18.1 22.0 11.9 28.6 11.0 20.5 20.8 23.1 28.4 18.5 14.2 48.3 27.8 24.6 21.1 46.8 9.9 57.1 25.6 20.5 11.6 19.6 14.7 19.2 27.1 25.1 52.1 15.2 9.2 32.0 27.1 62.1 14.7 34.5 12.6 26.3 17.3 36.0 14.6 24.8 30.2 25.9 25.2 17.4 26.1 21.3 15.6 25.6 22.3 37.0 28.6 14.3 14.9 26.5 17.1 16.9 17.3 27.3 15.8 7.2 3.9 15.5 5.7 2.7 6.3 2.5 4.3 7.5 2.6 4.1 5.2 4.8 17.4 5.4 1.9 3.0 3.7 2.5 28.9 29.1 33.3 40.9 28.8 25.6 28.0 27.5 28.1 23.1 29.2 28.9 14.5 22.4 37.5 37.5 22.7 8.3 8.9 11.0 13.1 33.3 14.2 10.8 18.5 4.3 9.1 9.2 89.6 17.4 24.6 19.9 7.9 11.6 16.6 43.6 19.6 15.1 14.8 18.3 54.2 9.7 6.9 16.4 29.6 26.8 17.7 21.1 13.2 9.4 21.7 33.7 39.4 13.0 20.3 12.6 16.2 16.0 21.5 16.1 10.6 20.6 19.2 14.5 44.3 21.1 35.9 10.8 6.6 19.9 24.4 7.1 8.8 7.9 24.4 50.1 19.7 14.6 32.6 60.7 41.6 13.6 9.5 22.4 36.5 18.4 13.8 7.3 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 GGT5 "GGT-REL, GGTLA1" ENSG00000099998 "Gamma-glutamyltransferase 5" P36269 22 24219654-24245108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis, Leukotriene biosynthesis" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 42.8;Fibroblasts: 58.3;Leydig cells: 36.4;Sertoli cells: 184.1;Smooth muscle cells: 85.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3;eosinophil: 4.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 164.9;ASC TERT1: 124.4;HHSteC: 234.7;HSkMC: 271.7;TIME: 110.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008121, CAB032489" Uncertain Approved "Nucleoli fibrillar center" "Intracellular and membrane" NA NA 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoli fibrillar center" "CAB032489: AB_2111010, HPA008121: AB_1078965" "unprognostic (8.14e-2)" "unprognostic (2.53e-1)" "unprognostic (5.66e-2)" "unprognostic (9.94e-2)" "unprognostic (8.13e-2)" "unprognostic (8.21e-2)" "unprognostic (2.33e-2)" "unprognostic (2.90e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-1)" "unprognostic (8.37e-2)" "unprognostic (7.94e-2)" "prognostic unfavorable (6.36e-5)" "prognostic unfavorable (4.06e-4)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.79e-1)" "unprognostic (8.33e-2)" 137.6 60.5 39.0 18.6 39.3 1.4 90.6 37.6 41.7 73.2 32.8 27.8 19.4 54.4 12.9 19.6 70.6 37.2 93.4 35.0 45.1 78.2 55.2 37.7 48.0 52.2 46.3 26.6 25.8 13.2 41.1 11.9 46.9 49.3 12.0 2.1 37.1 20.9 23.1 40.1 40.8 32.2 41.9 36.1 40.0 9.6 45.3 10.4 110.2 16.6 18.3 45.1 64.2 38.2 0.0 1.8 0.6 0.0 164.9 124.4 1.1 2.9 0.2 0.1 0.0 0.1 0.1 0.2 3.4 0.2 0.3 0.3 0.1 0.1 0.0 2.2 0.9 6.7 1.0 24.1 234.7 3.0 6.4 271.7 0.1 3.4 3.2 0.4 45.8 0.7 0.4 1.2 44.1 0.4 0.0 22.4 3.6 1.1 0.0 0.1 4.0 1.0 6.1 0.0 0.4 5.9 0.1 7.3 0.1 22.7 1.0 1.7 110.8 0.1 2.3 0.1 0.0 0.3 1.5 0.2 3.9 5.7 0.2 2.3 0.5 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.2 39.0 39.3 37.6 41.7 35.0 45.1 52.2 46.3 46.9 41.9 45.3 38.2 27.2 3.2 16.0 1.0 0.3 7.0 3.3 3.2 0.0 0.0 7.2 4.2 4.4 0.0 17.9 0.0 0.0 0.2 0.4 0.0 0.0 0.6 0.8 0.3 8.3 42.8 0.0 2.7 0.1 0.2 0.2 58.3 1.1 0.4 1.3 0.0 33.5 0.1 2.1 0.0 0.1 0.0 0.0 1.0 12.5 3.3 36.4 1.8 3.6 22.5 3.3 0.3 0.0 0.5 0.0 0.4 0.0 23.7 0.3 2.2 0.0 0.1 2.2 1.0 184.1 33.9 85.6 0.6 0.4 0.3 4.4 0.3 1.1 2.1 0.0 1.4 SPECC1L "CYTSA, KIAA0376" ENSG00000100014 "Sperm antigen with calponin homology and coiled-coil domains 1 like" Q69YQ0 22 24270817-24417739 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA070614 Uncertain Supported "Actin filaments" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Actin filaments" "HPA070614: AB_2686287" "unprognostic (3.54e-1)" "unprognostic (4.93e-3)" "unprognostic (1.62e-1)" "unprognostic (5.88e-2)" "unprognostic (3.74e-2)" "unprognostic (1.28e-1)" "unprognostic (2.54e-1)" "unprognostic (7.82e-3)" "unprognostic (4.98e-2)" "unprognostic (1.72e-3)" "prognostic favorable (7.92e-4)" "unprognostic (3.15e-3)" "unprognostic (6.20e-3)" "unprognostic (1.40e-1)" "unprognostic (3.71e-1)" "unprognostic (5.79e-3)" "unprognostic (1.41e-1)" 13.0 13.1 12.3 12.4 12.8 13.3 13.8 34.0 13.5 16.6 17.7 15.8 7.8 15.9 9.7 17.5 15.5 12.5 18.6 10.8 15.7 14.6 14.4 17.2 12.5 18.1 16.2 22.0 13.3 17.3 14.6 10.1 18.9 20.1 16.9 10.7 16.2 15.1 12.7 9.2 11.6 19.0 15.8 11.1 11.5 31.9 16.6 14.5 24.0 13.1 13.8 14.9 13.0 13.7 31.1 22.8 42.9 23.7 40.1 39.2 14.5 43.1 34.1 36.8 36.4 25.5 8.4 44.9 10.3 39.5 29.0 27.0 39.2 24.2 43.4 26.1 21.1 28.5 12.9 23.4 26.7 51.2 27.0 33.1 19.2 32.8 34.2 28.8 44.0 18.9 24.5 19.0 39.3 17.3 26.6 18.5 20.7 22.5 17.1 24.0 43.3 16.1 18.4 23.3 37.2 38.3 36.5 27.5 23.8 37.1 18.3 14.4 46.3 77.2 43.7 19.3 29.3 22.7 23.4 20.0 22.6 19.0 29.2 3.9 2.4 4.8 3.3 3.5 2.5 2.8 2.2 1.6 2.3 3.1 2.7 2.9 3.2 1.3 1.6 3.7 1.6 1.9 12.3 12.8 34.0 13.5 10.8 15.7 18.1 16.2 18.9 15.8 16.6 13.7 11.6 16.0 21.3 0.0 10.4 3.6 2.7 5.0 10.2 8.4 13.8 9.4 13.7 14.3 9.1 12.9 10.4 7.3 7.9 32.8 1.9 6.7 26.9 8.3 14.9 12.0 14.4 7.6 0.0 7.4 3.2 11.4 8.2 9.8 16.5 13.4 15.7 11.4 7.3 10.1 0.0 12.2 14.2 7.3 2.2 93.7 16.1 6.9 14.2 0.0 14.8 6.4 9.2 0.0 0.0 9.0 15.0 13.5 10.7 5.7 8.9 6.1 11.9 8.5 13.1 11.3 12.5 24.1 28.5 9.8 3.1 5.9 9.3 7.6 8.0 3.8 ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;brain: 101.4;lymphoid tissue: 54.1" "Group enriched" "Detected in some" 6 "B-cells: 5.8;monocytes: 10.9;Plasma cells: 11.8;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 5 "basal ganglia: 101.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 39.3;Karpas-707: 52.8;RPMI-8226: 41.1;SK-BR-3: 74.0;U-266/70: 52.8;U-266/84: 74.4;U-698: 55.0" "Region enriched" "Detected in many" 9 "basal ganglia: 399.8" "Region enriched" "Detected in many" 50 "basal ganglia: 142.2" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" 3.4 5.4 12.3 13.5 101.4 40.6 2.5 10.8 19.2 4.0 8.0 4.1 6.6 2.9 1.6 2.0 3.7 3.0 13.5 11.6 10.0 17.5 14.5 14.6 20.5 10.2 10.4 3.9 2.3 0.2 6.7 1.8 10.4 5.5 1.0 2.1 3.2 1.7 2.5 1.6 7.0 0.9 9.9 15.2 4.0 3.1 19.9 54.1 4.3 1.4 10.4 5.3 3.4 9.7 0.5 0.9 1.0 0.3 0.4 0.3 1.0 0.7 23.2 1.3 2.4 4.5 0.3 39.3 2.6 0.7 2.4 1.0 2.4 0.0 0.0 4.7 6.6 0.7 0.2 5.6 0.4 0.8 18.7 0.2 0.2 7.2 0.0 0.5 8.2 5.8 0.3 52.8 0.0 0.7 14.0 4.2 1.6 5.0 0.1 0.6 1.7 41.1 0.1 0.3 3.9 21.6 1.1 74.0 0.3 1.1 0.8 3.7 0.5 2.2 3.7 0.5 0.4 52.8 74.4 55.0 11.5 13.6 0.3 9.6 2.1 11.6 20.0 6.5 46.9 21.9 37.4 39.2 2.6 38.3 51.5 42.4 32.6 6.3 23.1 2.9 54.0 27.1 12.3 101.4 10.8 19.2 11.6 10.0 10.2 10.4 10.4 9.9 19.9 9.7 0.0 0.0 0.5 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.2 0.0 0.0 0.5 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.1 UPB1 BUP1 ENSG00000100024 "Beta-ureidopropionase 1" Q9UBR1 22 24494107-24528390 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 216.0" "Group enriched" "Detected in many" 5 "Hepatocytes: 146.5;Proximal tubular cells: 68.5" "Cancer enriched" "Detected in some" 8 "liver cancer: 25.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.8" "Group enriched" "Detected in some" 14 "basophil: 2.1;neutrophil: 2.1" "Lineage enriched" "Detected in single" 14 "granulocytes: 2.1" "Cell line enriched" "Detected in single" 7 "CACO-2: 3.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA000728, HPA076321" Enhanced NA NA 1400000 "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA000728: AB_1080471, HPA076321: " "unprognostic (7.27e-2)" "unprognostic (4.57e-3)" "unprognostic (2.27e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (1.09e-4)" "prognostic favorable (2.30e-7)" "unprognostic (8.41e-2)" "unprognostic (1.06e-1)" "unprognostic (2.93e-1)" "unprognostic (4.89e-6)" "unprognostic (3.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.81e-1)" "unprognostic (2.56e-1)" "unprognostic (1.99e-1)" "unprognostic (4.63e-3)" 0.2 0.2 0.2 0.2 0.6 2.0 0.1 0.7 1.8 0.2 0.2 0.2 1.2 0.2 0.2 0.1 0.3 0.1 1.9 0.2 0.0 25.7 216.0 0.8 0.2 0.1 0.1 0.2 0.1 0.0 0.4 0.0 0.4 0.3 0.1 1.1 0.1 0.1 0.5 0.9 0.4 0.1 0.0 0.8 0.2 3.0 0.4 0.6 0.1 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.4 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.7 1.8 0.2 0.0 0.1 0.1 0.4 0.0 0.4 0.1 0.8 0.0 2.0 0.3 0.6 0.6 1.3 0.1 0.0 4.0 0.3 0.3 2.4 4.3 0.0 1.8 10.4 0.1 0.1 0.0 11.7 0.1 1.2 0.2 0.6 1.9 2.4 5.3 0.7 0.4 0.1 1.4 0.0 0.5 0.0 0.6 3.6 146.5 0.1 0.0 1.2 0.0 0.0 5.1 2.7 1.4 0.3 1.0 0.0 0.0 21.3 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.7 1.2 0.0 68.5 0.0 1.8 0.0 2.7 3.7 12.8 6.8 0.0 1.1 0.3 0.9 0.2 0.1 1.1 GUCD1 "C22orf13, LLN4, MGC1842" ENSG00000138867 "Guanylyl cyclase domain containing 1" Q96NT3 22 24540423-24555935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 161.3;Proximal enterocytes: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022786 Approved Nucleoplasm NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "HPA022786: AB_1845711" "unprognostic (1.58e-1)" "prognostic favorable (6.84e-4)" "unprognostic (2.83e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.51e-2)" "unprognostic (1.61e-1)" "unprognostic (3.96e-2)" "unprognostic (1.89e-1)" "prognostic favorable (7.26e-4)" "unprognostic (1.28e-1)" "unprognostic (3.55e-2)" "unprognostic (1.76e-2)" "unprognostic (4.36e-2)" "unprognostic (8.63e-2)" "unprognostic (1.59e-1)" "unprognostic (3.01e-2)" 36.9 27.5 19.3 25.3 22.0 89.9 29.2 20.5 18.9 19.6 17.7 37.5 67.5 19.1 16.7 25.2 21.1 25.4 62.0 17.0 19.8 43.0 93.9 34.3 34.6 23.4 23.4 19.4 37.1 24.1 12.3 21.6 21.3 31.0 36.2 10.9 25.0 20.2 96.4 27.6 59.6 23.1 22.1 30.4 37.1 18.8 23.1 27.9 16.6 117.6 36.9 26.8 19.8 22.2 40.8 37.1 30.9 38.5 62.5 58.4 25.7 38.7 59.5 63.3 61.0 56.9 30.2 72.1 26.0 50.9 39.3 51.2 35.2 43.3 33.6 74.2 45.4 31.3 36.1 51.3 50.6 83.2 63.2 59.6 33.9 64.0 29.0 38.7 67.5 35.9 32.3 75.6 48.4 47.2 49.2 34.1 31.0 95.3 30.6 57.2 52.0 73.1 49.8 44.9 33.8 33.2 47.2 60.6 33.3 23.6 49.6 56.7 48.7 143.4 59.8 44.5 34.6 70.1 53.8 50.8 57.9 45.3 49.9 20.2 14.9 52.5 7.4 14.8 8.5 37.0 7.1 7.7 13.7 42.6 6.7 7.6 15.2 7.5 14.5 9.7 7.6 13.8 19.3 22.0 20.5 18.9 17.0 19.8 23.4 23.4 21.3 22.1 23.1 22.2 20.5 16.0 33.9 6.8 41.5 12.4 11.8 13.9 21.1 5.3 25.9 18.3 51.2 78.6 13.3 5.5 6.2 18.6 21.2 99.7 52.8 27.1 15.8 13.4 13.6 16.4 19.8 86.1 2.3 66.0 20.1 17.5 35.7 17.9 15.2 19.5 18.5 161.3 27.1 3.3 3.0 52.3 16.2 23.5 12.0 8.6 19.0 21.0 17.8 2.8 28.6 18.2 18.6 5.5 7.5 48.1 72.4 16.1 17.5 32.1 149.6 84.9 9.7 13.2 26.3 12.4 16.7 24.3 32.0 18.7 11.1 16.3 14.6 28.9 36.7 18.9 SNRPD3 "Sm-D3, SMD3" ENSG00000100028 "Small nuclear ribonucleoprotein D3 polypeptide" P62318 22 24555958-24582052 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA001170 Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 290000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nuclear bodies, Cytosol" "HPA001170: AB_1080042" "unprognostic (3.30e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (4.49e-2)" "unprognostic (2.03e-1)" "unprognostic (4.44e-2)" "unprognostic (1.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.52e-2)" "unprognostic (3.64e-2)" "unprognostic (2.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (1.65e-2)" 30.5 31.1 24.7 35.2 25.7 39.2 37.5 29.6 34.8 31.8 25.7 50.5 33.2 35.5 35.5 43.5 36.7 20.2 35.3 25.0 25.8 48.0 64.9 26.9 47.7 23.7 23.9 34.3 23.7 51.2 27.0 24.7 25.5 33.8 40.7 54.1 29.7 31.9 103.7 28.8 35.7 29.5 23.6 34.3 36.5 24.7 25.0 74.4 38.9 86.2 53.3 39.5 32.3 30.7 182.5 45.7 188.6 58.5 70.1 57.7 56.1 173.1 74.8 166.1 148.1 61.4 65.8 158.7 70.1 109.2 83.0 130.7 252.1 219.3 175.5 107.9 188.8 152.4 95.4 113.9 66.2 408.0 95.7 66.5 93.8 186.3 86.6 81.8 120.6 139.8 116.2 60.5 61.5 56.8 187.0 82.6 98.9 237.8 61.9 179.5 190.7 66.6 154.5 130.0 82.2 95.6 83.4 62.7 87.7 162.7 102.3 97.5 135.5 127.0 126.3 74.3 126.2 74.3 168.2 283.7 70.1 127.1 91.4 18.5 42.9 53.9 35.6 50.2 37.6 60.5 38.4 39.2 54.2 50.7 36.6 41.3 18.6 51.1 51.1 49.7 41.1 47.4 24.7 25.7 29.6 34.8 25.0 25.8 23.7 23.9 25.5 23.6 25.0 30.7 120.0 96.1 81.8 7.5 118.2 108.6 115.3 293.1 133.1 61.1 94.2 138.8 95.9 101.5 162.9 130.6 35.5 239.5 123.1 112.6 291.6 161.9 91.0 176.6 157.7 96.8 111.0 139.4 8.1 114.8 228.8 121.0 92.2 147.9 86.2 145.3 66.0 203.3 176.4 38.7 8.7 134.2 168.9 74.5 84.8 85.1 116.2 98.1 67.6 10.3 151.0 134.3 86.5 8.0 13.4 129.4 118.2 118.5 120.7 96.8 191.7 310.5 135.2 68.9 65.7 102.8 209.6 111.1 131.4 164.9 113.7 180.3 111.9 176.2 139.0 113.3 LRRC75B "C22orf36, FAM211B, MGC131773" ENSG00000178026 "Leucine rich repeat containing 75B" Q2VPJ9 22 24585620-24593208 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 34.3;Hepatocytes: 25.6;Muller glia cells: 39.9;Proximal enterocytes: 46.7;Proximal tubular cells: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 5.3;MCF7: 5.0;SH-SY5Y: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002540 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "HPA002540: AB_1079263" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.47e-1)" "unprognostic (2.34e-1)" "unprognostic (2.74e-2)" "unprognostic (5.21e-2)" "unprognostic (4.52e-2)" "unprognostic (2.48e-2)" "unprognostic (2.49e-1)" "unprognostic (2.48e-2)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.74e-1)" "unprognostic (1.28e-1)" "unprognostic (7.40e-2)" "unprognostic (9.69e-2)" 1.8 0.7 5.8 0.0 5.5 0.3 1.8 5.7 7.4 1.9 3.6 3.2 0.0 1.0 0.5 2.1 1.5 0.0 2.9 5.2 6.0 5.6 3.6 0.8 0.0 6.0 6.1 3.2 3.5 0.0 1.3 0.1 5.7 2.8 0.1 0.6 2.0 0.4 2.5 1.8 1.6 0.0 5.9 0.5 2.5 7.5 5.9 0.1 1.6 0.0 0.1 3.5 1.9 5.8 0.1 2.8 0.0 1.5 0.3 1.1 0.2 0.4 0.4 0.9 1.0 2.0 0.0 0.0 0.7 0.8 0.8 3.0 0.2 1.5 0.0 0.9 1.8 0.2 0.3 5.3 2.6 0.0 0.0 0.0 1.1 1.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 5.0 0.0 1.0 1.3 3.4 1.1 0.0 0.1 0.0 1.2 0.3 1.4 4.2 1.4 0.4 0.5 0.3 0.0 0.5 1.5 1.6 0.9 0.6 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.8 5.5 5.7 7.4 5.2 6.0 6.0 6.1 5.7 5.9 5.9 5.8 1.6 12.8 5.9 9.4 0.3 0.0 2.5 0.0 2.2 2.8 16.2 18.7 4.4 34.3 0.0 7.3 0.0 2.5 0.9 10.7 11.7 9.8 1.6 2.3 3.6 1.8 1.2 1.3 3.8 8.9 0.4 7.1 14.3 6.1 0.0 7.2 2.9 25.6 1.1 1.7 4.1 8.0 0.0 1.6 0.0 7.9 12.8 1.4 0.0 1.0 0.3 39.9 0.0 7.1 2.2 4.0 6.2 9.8 0.6 8.0 46.7 44.5 0.0 1.8 0.0 4.5 4.2 0.5 1.3 2.5 0.0 1.1 0.8 2.0 6.4 1.3 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 PIWIL3 HIWI3 ENSG00000184571 "Piwi like RNA-mediated gene silencing 3" Q7Z3Z3 22 24719034-24774720 "Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 8 "Early spermatids: 23.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061955 Uncertain NA NA "Cluster 29: Early spermatids - Spermatogenesis" "HPA061955: AB_2684647" "unprognostic (9.05e-2)" "unprognostic (2.20e-1)" "unprognostic (3.12e-4)" "unprognostic (2.73e-1)" "unprognostic (7.33e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SGSM1 "KIAA1941, RUTBC2" ENSG00000167037 "Small G protein signaling modulator 1" Q2NKQ1 22 24806169-24927578 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.5;heart muscle: 11.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 97.0;Inhibitory neurons: 76.4;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 58.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 2.9;RPMI-8226: 2.2;SCLC-21H: 2.0;SH-SY5Y: 1.3;U-266/84: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003986 Approved NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA003986: AB_1856513" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (1.97e-2)" "unprognostic (1.40e-4)" "unprognostic (4.79e-3)" "unprognostic (6.43e-2)" "unprognostic (1.39e-3)" "unprognostic (1.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.50e-2)" "unprognostic (2.23e-3)" "unprognostic (1.37e-1)" "unprognostic (2.61e-6)" "unprognostic (1.46e-1)" "unprognostic (4.66e-1)" "unprognostic (2.25e-2)" "unprognostic (3.93e-2)" 0.5 3.3 12.5 0.4 11.5 0.2 0.9 6.8 12.9 1.2 4.3 2.0 0.4 0.6 1.0 0.3 4.7 0.6 11.5 10.1 20.5 1.8 0.1 1.1 0.4 11.2 15.4 1.8 3.6 7.8 10.5 0.3 19.0 1.6 1.6 1.5 1.3 0.8 0.6 3.2 0.9 0.5 7.5 0.3 2.9 1.8 18.2 0.3 2.1 0.2 0.3 1.7 1.1 9.4 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 2.9 0.3 0.0 0.0 2.2 0.0 0.3 2.0 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.1 12.5 11.5 6.8 12.9 10.1 20.5 11.2 15.4 19.0 7.5 18.2 9.4 1.4 3.2 6.9 2.6 0.7 3.8 9.8 0.1 2.2 3.2 1.5 1.9 26.4 1.5 1.5 5.5 4.2 0.3 3.2 3.1 3.9 1.7 0.5 10.3 0.9 3.7 17.3 0.0 97.0 1.9 0.1 4.5 7.1 6.6 1.3 0.1 11.4 0.1 1.9 1.7 76.4 6.4 0.0 0.3 8.4 0.5 0.3 0.8 10.6 12.2 0.1 2.1 5.2 33.7 58.6 1.3 5.4 0.4 0.5 5.6 0.5 0.7 1.5 1.5 13.1 3.1 2.5 1.2 7.9 0.4 3.8 0.3 2.3 0.3 4.8 4.8 TMEM211 bA9F11.1 ENSG00000206069 "Transmembrane protein 211" Q6ICI0 22 24934954-24946695 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 2.6;salivary gland: 5.8;stomach 1: 3.2" "Cell type enriched" "Detected in some" 19 "Ionocytes: 36.7" "Group enriched" "Detected in some" 5 "colorectal cancer: 4.8;endometrial cancer: 3.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA066784 Uncertain NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA066784: AB_2685722" "unprognostic (7.89e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.09e-2)" "unprognostic (5.97e-3)" "unprognostic (5.88e-2)" "unprognostic (1.31e-3)" "unprognostic (3.26e-2)" "unprognostic (2.06e-1)" "unprognostic (6.42e-2)" "unprognostic (2.65e-2)" "unprognostic (8.61e-3)" "unprognostic (3.59e-1)" "unprognostic (4.43e-2)" 0.0 0.0 0.1 0.3 0.3 0.0 0.4 0.3 0.2 2.6 0.0 0.3 0.0 0.6 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 5.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 1.3 1.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 36.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 KIAA1671 ENSG00000197077 KIAA1671 Q9BY89 22 24952730-25197448 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 74.4;Excitatory neurons: 67.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.8" "Lineage enriched" "Detected in single" 4 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "OE19: 39.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018135 Approved Approved Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Microtubules "HPA018135: AB_1859551" "unprognostic (1.67e-1)" "unprognostic (1.65e-3)" "unprognostic (1.14e-2)" "unprognostic (1.46e-2)" "unprognostic (7.34e-2)" "unprognostic (3.52e-2)" "unprognostic (8.71e-3)" "unprognostic (1.26e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (2.66e-2)" "unprognostic (7.68e-2)" "prognostic favorable (3.19e-6)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (7.54e-2)" "unprognostic (7.87e-2)" 10.7 13.7 12.4 5.1 13.2 0.8 22.5 2.8 17.9 10.3 8.6 16.0 14.4 6.6 5.2 25.9 20.0 14.8 11.3 20.0 7.7 11.0 34.1 12.2 5.5 6.7 8.3 8.5 10.1 10.3 11.2 4.1 3.9 13.2 14.2 15.5 25.9 15.5 25.1 28.0 16.8 6.8 6.5 3.8 12.4 4.9 13.5 15.6 26.6 22.1 8.9 8.9 18.7 5.6 25.2 15.7 3.3 5.9 0.1 0.1 2.6 0.1 0.1 1.4 0.1 12.6 9.0 0.1 11.7 1.1 6.9 29.8 25.5 25.2 1.0 0.2 10.6 0.1 16.7 16.9 3.3 0.1 1.3 0.6 22.4 7.9 24.3 16.6 28.9 0.5 0.3 0.1 3.4 11.6 0.1 0.1 5.2 39.9 8.3 1.1 26.6 4.9 16.3 10.8 8.0 6.7 20.3 14.0 1.3 10.8 7.6 0.2 19.5 1.4 27.0 16.6 4.5 0.1 0.4 0.1 10.0 0.0 4.3 0.2 0.0 0.0 1.8 0.0 0.2 0.0 0.5 1.3 0.0 0.1 0.2 0.8 0.2 0.4 0.0 0.1 0.1 0.3 12.4 13.2 2.8 17.9 20.0 7.7 6.7 8.3 3.9 6.5 13.5 5.6 27.7 12.8 21.9 74.4 1.1 10.8 21.1 16.2 18.2 4.2 25.4 16.5 11.9 25.8 19.2 5.5 22.9 0.2 3.0 62.9 0.0 18.9 2.6 31.2 3.5 28.5 7.2 5.3 67.8 18.9 0.1 4.9 22.4 30.2 1.3 4.2 29.6 47.8 2.4 16.8 22.9 12.3 6.1 1.9 5.9 3.5 7.2 1.6 10.6 43.1 0.6 21.6 0.0 12.5 3.4 21.4 34.1 9.1 0.6 18.2 34.1 8.8 32.0 17.6 0.0 11.0 9.3 6.8 8.8 27.3 14.5 1.0 6.6 6.6 20.1 29.2 CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Distal enterocytes: 2.6;Distal tubular cells: 1.9;granulocytes: 4.5;Muller glia cells: 4.3;Proximal tubular cells: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.4;HEK 293: 1.4;HeLa: 1.8;hTERT-HME1: 1.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: AB_2682939" "unprognostic (1.36e-2)" "unprognostic (6.27e-4)" "unprognostic (6.30e-3)" "unprognostic (5.34e-2)" "unprognostic (8.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.45e-2)" "unprognostic (2.07e-2)" "unprognostic (4.15e-2)" "unprognostic (8.28e-2)" "unprognostic (2.40e-1)" "unprognostic (2.68e-2)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-3)" 0.2 0.5 0.9 0.1 0.6 0.0 0.7 0.0 1.0 0.5 0.0 0.6 0.3 0.3 0.2 0.6 0.4 0.4 0.5 0.9 0.0 2.0 2.0 0.3 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.1 0.0 0.8 0.4 0.7 1.0 0.4 0.7 0.9 0.7 0.1 0.0 0.1 0.5 0.2 0.5 0.2 1.3 0.1 0.3 0.1 0.4 0.0 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.2 1.4 0.8 0.6 0.0 0.0 1.4 0.0 1.8 1.0 0.0 0.0 0.0 0.0 0.7 0.4 1.2 0.2 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 1.1 0.0 0.1 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.5 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 1.0 0.9 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.6 0.3 0.4 1.5 0.1 0.0 0.0 0.0 0.0 2.6 1.9 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 4.5 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 1.3 10.5 0.4 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.3 0.0 0.1 0.0 0.3 0.1 CRYBB2 "CCA2, CRYB2, CRYB2A" ENSG00000244752 "Crystallin beta B2" P43320 22 25212564-25231870 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5" "Cell type enhanced" "Detected in many" "Breast glandular cells: 10.6;Breast myoepithelial cells: 12.8;Distal tubular cells: 27.4;Melanocytes: 12.4" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 2.1" "Region enhanced" "Detected in some" "hippocampal formation: 1.7" "Low region specificity" "Detected in many" HPA043749 Supported Approved Nucleoplasm NA NA "Cluster 65: Brain - Ion transport" "Cluster 20: HeLa - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "HPA043749: AB_2678652" "unprognostic (1.28e-1)" "unprognostic (2.71e-2)" "unprognostic (4.09e-2)" "unprognostic (1.95e-1)" "unprognostic (5.06e-2)" "unprognostic (7.04e-2)" "unprognostic (8.57e-3)" "unprognostic (9.51e-3)" "unprognostic (8.55e-2)" "unprognostic (2.46e-2)" "unprognostic (4.13e-2)" "unprognostic (2.01e-1)" "unprognostic (1.73e-5)" "unprognostic (1.44e-2)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (9.89e-3)" 0.2 0.4 2.7 0.0 2.6 0.0 0.3 2.0 4.5 0.3 2.0 0.4 0.2 0.1 0.3 0.4 0.1 0.1 0.2 2.7 2.3 0.5 0.3 0.3 0.0 2.1 2.2 0.1 0.2 0.0 1.4 0.0 2.5 0.6 0.3 0.4 0.3 0.1 0.5 0.4 0.3 0.2 2.0 0.1 0.2 1.7 2.9 0.0 1.0 0.0 0.0 0.2 0.4 2.5 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.9 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.0 2.7 2.6 2.0 4.5 2.7 2.3 2.1 2.2 2.5 2.0 2.9 2.5 0.9 0.0 0.0 2.0 1.0 5.4 0.6 6.7 0.6 0.3 10.6 12.8 1.4 1.5 1.5 1.8 0.0 0.1 0.9 1.7 27.4 0.1 3.0 1.7 1.2 2.9 0.0 8.0 2.4 0.2 0.1 3.4 0.0 2.5 0.0 3.1 4.6 3.2 0.2 0.0 0.4 0.3 0.0 1.2 3.1 9.6 2.5 0.8 12.4 1.9 0.0 0.4 0.0 0.5 0.3 0.5 0.1 8.2 0.0 0.4 0.0 9.7 0.6 0.1 0.0 6.2 2.1 2.6 3.3 0.4 3.8 0.1 1.3 7.6 0.2 0.6 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 MYO18B BK125H2.1 ENSG00000133454 "Myosin XVIIIB" Q8IUG5 22 25742144-26031045 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 120.8;skeletal muscle: 262.7;tongue: 55.6" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 95.5;Early spermatids: 61.4;Late spermatids: 37.3;Skeletal myocytes: 32.8" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.8" "Region enhanced" "Detected in single" "thalamus: 2.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 10.6;REH: 15.0;RH-30: 30.5;U-2 OS: 13.2;U-266/70: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA000953 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Centrosome" "HPA000953: AB_1079440" "unprognostic (3.28e-2)" "unprognostic (1.79e-1)" "unprognostic (1.86e-2)" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-2)" "unprognostic (5.93e-4)" "unprognostic (2.46e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (4.36e-3)" "unprognostic (2.96e-3)" "unprognostic (3.93e-7)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.65e-1)" 0.2 0.1 0.3 0.1 0.1 1.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 120.8 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.8 0.0 0.1 0.0 0.2 0.0 0.3 1.0 0.0 0.0 2.7 0.0 262.7 0.5 0.0 0.0 0.2 0.0 1.5 10.2 2.3 1.9 0.1 55.6 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 5.3 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.0 4.0 0.0 0.4 1.6 0.0 0.0 0.0 15.0 30.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13.2 0.0 0.0 9.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.1 0.3 0.3 0.8 0.3 0.2 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.4 0.0 0.2 1.2 0.0 0.0 1.8 0.0 0.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 37.3 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 ASPHD2 FLJ39838 ENSG00000128203 "Aspartate beta-hydroxylase domain containing 2" Q6ICH7 22 26429260-26445015 "Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.9;skin 1: 11.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.8;Early spermatids: 25.3;Late spermatids: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.3" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;monocytes: 5.3" "Cell line enhanced" "Detected in many" "Karpas-707: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000820 Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "HPA000820: AB_1078231" "unprognostic (1.12e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (2.71e-1)" "unprognostic (1.94e-1)" "unprognostic (9.07e-2)" "unprognostic (2.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.24e-2)" "unprognostic (8.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.79e-1)" "prognostic unfavorable (4.06e-5)" "unprognostic (6.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.09e-2)" "unprognostic (1.11e-2)" 0.7 0.6 8.0 2.5 16.9 1.5 0.6 10.4 9.0 1.5 0.6 2.0 1.2 1.2 6.2 1.5 0.5 1.1 0.4 8.3 7.0 6.1 0.3 0.9 4.4 4.1 4.3 0.6 0.5 1.7 6.6 1.1 5.5 1.1 2.0 5.6 1.0 0.7 0.4 11.1 1.6 0.7 3.1 2.8 8.2 1.9 6.4 1.3 2.0 0.1 3.3 2.3 1.1 5.8 1.6 0.9 4.1 6.5 0.6 0.3 2.2 2.1 4.5 4.3 6.2 0.0 0.4 1.4 0.5 2.0 4.3 1.9 4.5 7.2 2.3 9.7 6.1 0.3 0.0 0.3 4.1 2.4 1.1 0.7 3.4 2.2 3.0 4.7 4.6 3.6 1.7 21.9 1.3 0.4 1.8 1.0 4.0 8.5 0.9 12.2 2.3 3.7 6.0 0.6 11.0 4.8 2.1 0.3 2.4 2.2 0.2 3.5 4.3 2.7 13.4 0.6 4.4 6.3 1.7 2.8 4.1 8.6 1.8 0.0 1.2 0.5 0.3 3.3 0.9 0.9 0.7 0.7 2.1 0.9 0.4 0.4 0.3 0.0 5.3 2.4 0.4 0.4 8.0 16.9 10.4 9.0 8.3 7.0 4.1 4.3 5.5 3.1 6.4 5.8 0.3 0.0 1.1 4.2 5.1 1.8 1.4 2.1 0.0 24.8 0.9 0.9 0.6 1.5 0.9 0.0 10.4 0.3 6.8 3.3 0.0 1.2 25.3 0.7 0.5 1.1 0.0 0.0 14.1 0.7 13.2 1.3 8.2 1.5 0.0 0.9 1.1 0.1 1.5 6.7 9.7 4.3 2.0 2.8 5.7 25.1 0.9 4.1 1.8 1.0 5.3 2.4 2.1 4.5 1.1 5.9 0.8 0.7 12.1 4.6 0.1 0.7 0.8 11.3 0.0 0.4 0.7 1.1 3.3 0.6 1.1 1.1 2.8 0.4 2.0 4.2 HPS4 "BLOC3S2, KIAA1667, LE" ENSG00000100099 "HPS4 biogenesis of lysosomal organelles complex 3 subunit 2" Q9NQG7 22 26443423-26483837 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Rod photoreceptor cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 86.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033106, HPA050189" Approved Approved Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" Centrosome "CAB033106: AB_2264349, HPA050189: AB_2681046" "unprognostic (1.55e-2)" "unprognostic (1.02e-1)" "unprognostic (9.82e-2)" "unprognostic (5.30e-3)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (1.83e-3)" "unprognostic (1.59e-1)" "unprognostic (2.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (2.23e-2)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (6.46e-2)" 6.6 8.9 10.4 6.5 11.4 10.3 6.7 11.1 10.5 9.0 12.2 6.7 5.4 6.9 7.7 9.9 9.2 6.1 4.5 10.3 11.5 8.6 8.5 6.5 8.5 10.9 10.8 12.1 12.7 12.1 11.0 5.6 11.2 8.3 5.5 7.6 6.6 7.7 4.6 14.0 7.3 7.1 10.7 9.0 8.1 13.1 11.4 13.0 9.8 5.0 9.6 6.9 8.4 10.5 16.3 7.5 15.5 15.9 11.5 13.6 8.2 9.7 18.8 21.4 19.1 7.9 7.8 15.4 7.5 11.8 12.1 13.2 14.9 21.0 19.3 11.4 15.4 15.6 6.3 13.3 20.5 18.4 17.0 13.3 17.1 19.5 34.5 18.1 14.2 25.5 17.4 19.0 15.7 6.9 31.2 6.2 9.3 15.0 8.0 86.3 18.3 20.4 9.9 10.1 17.6 13.0 9.4 10.6 46.7 11.6 11.5 13.9 8.8 24.8 46.2 12.4 12.2 28.1 23.4 50.5 16.2 11.8 16.3 10.8 3.2 3.1 4.8 2.3 4.5 5.5 3.9 4.1 4.3 4.7 4.5 5.0 1.1 7.2 2.1 5.7 2.8 4.7 10.4 11.4 11.1 10.5 10.3 11.5 10.9 10.8 11.2 10.7 11.4 10.5 16.6 12.8 32.4 28.7 38.7 12.5 28.3 28.9 17.1 52.6 14.4 12.4 6.3 17.2 25.5 42.3 114.7 21.7 31.7 11.6 17.6 20.4 24.3 16.3 17.2 18.6 26.5 48.1 18.4 27.1 19.4 14.1 28.1 14.1 42.4 40.6 22.5 14.2 24.8 43.7 31.1 20.1 44.7 18.3 12.2 24.3 32.6 19.1 48.0 19.7 14.9 23.7 21.6 32.6 36.4 45.0 13.6 19.9 25.1 29.4 18.0 15.7 28.1 119.3 0.0 16.0 12.2 32.3 46.6 11.1 14.9 20.0 20.6 23.6 21.4 26.9 SRRD "HC/HCC, SRR1L" ENSG00000100104 "SRR1 domain containing" Q9UH36 22 26483877-26494658 "Predicted intracellular proteins" "Biological rhythms, Heme biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 49.0;Late spermatids: 54.9;Pancreatic endocrine cells: 48.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002945 Uncertain Approved Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 1: Pancreatic cells - Digestion" Cytosol "HPA002945: AB_1079265" "unprognostic (3.25e-1)" "unprognostic (3.01e-2)" "unprognostic (1.65e-2)" "unprognostic (1.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (2.16e-6)" "unprognostic (9.00e-2)" "unprognostic (8.51e-3)" "unprognostic (2.49e-2)" "unprognostic (4.50e-3)" "unprognostic (3.93e-2)" "unprognostic (2.63e-1)" "unprognostic (2.70e-1)" "unprognostic (1.03e-1)" "unprognostic (1.76e-3)" "unprognostic (2.96e-1)" 5.0 3.5 8.4 4.1 8.8 6.2 6.2 10.4 9.7 5.5 6.2 6.0 3.6 6.3 6.1 5.3 5.5 3.7 7.6 8.7 8.0 6.4 6.9 5.3 5.6 8.2 8.2 7.1 5.5 6.7 5.1 5.3 7.7 6.8 5.2 5.8 4.9 7.2 19.6 6.0 3.9 7.0 8.1 5.4 4.9 4.8 8.6 5.7 10.5 17.1 7.3 5.5 4.2 8.6 10.7 6.3 10.6 10.9 10.8 6.5 6.1 7.4 10.4 14.7 13.5 6.2 4.6 23.6 5.1 9.7 7.4 9.5 16.6 15.6 14.3 12.2 16.5 10.4 5.5 10.1 7.6 23.1 7.8 6.2 13.4 10.5 16.4 9.7 12.9 13.8 17.2 14.5 9.7 9.2 10.4 7.3 6.6 11.7 7.9 23.3 13.2 17.0 9.7 7.6 11.2 7.6 8.5 7.6 19.7 8.8 9.1 9.0 9.9 11.3 37.2 6.4 13.1 9.5 8.3 19.4 7.7 9.4 15.0 0.3 0.5 0.2 0.7 0.4 1.0 1.1 0.8 1.0 0.5 0.6 1.1 1.2 0.4 0.9 0.4 0.4 0.2 0.3 8.4 8.8 10.4 9.7 8.7 8.0 8.2 8.2 7.7 8.1 8.6 8.6 12.1 0.0 6.4 3.6 10.6 29.7 16.2 7.5 3.4 13.0 10.0 10.5 3.0 12.8 5.9 1.8 2.1 13.3 5.9 3.7 9.8 24.9 22.4 5.8 10.6 11.2 4.8 46.9 3.1 49.0 22.9 8.9 7.7 8.9 11.4 15.1 11.0 15.4 14.1 13.5 3.0 4.5 2.0 3.8 8.6 54.9 7.2 8.6 8.8 1.0 6.1 9.8 10.3 3.5 1.9 48.9 2.4 9.1 10.4 12.1 3.4 19.9 3.2 9.3 6.6 12.6 10.3 17.8 12.9 7.7 31.8 16.7 9.1 21.7 5.9 14.7 TFIP11 "DKFZP434B194, Spp382, TIP39" ENSG00000100109 "Tuftelin interacting protein 11" Q9UBB9 22 26491225-26512505 "Plasma proteins, Predicted intracellular proteins" "Biomineralization, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027085 Approved Nucleoplasm,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA027085: AB_1857964" "unprognostic (1.53e-1)" "unprognostic (1.86e-1)" "unprognostic (4.87e-2)" "unprognostic (9.14e-2)" "unprognostic (3.24e-2)" "unprognostic (3.86e-2)" "unprognostic (6.28e-2)" "unprognostic (2.63e-1)" "unprognostic (1.76e-1)" "unprognostic (3.01e-1)" "unprognostic (4.38e-2)" "unprognostic (2.34e-1)" "unprognostic (2.96e-3)" "unprognostic (1.46e-2)" "unprognostic (9.24e-2)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" 13.5 13.0 12.4 16.3 13.5 62.8 12.5 15.4 13.9 11.5 12.1 12.7 12.9 12.4 10.4 14.8 13.1 12.6 16.0 12.9 12.0 13.9 19.3 14.0 24.9 12.0 11.8 12.4 16.7 13.0 10.5 14.5 11.3 12.4 12.6 13.4 11.0 10.6 41.8 20.3 13.5 13.1 11.6 17.7 11.9 26.6 13.0 20.1 16.2 21.5 24.7 14.8 10.9 14.3 22.9 26.4 22.3 24.6 34.7 20.6 21.5 26.4 34.5 41.8 39.1 19.8 16.1 44.4 16.6 33.9 27.6 32.8 32.1 26.3 30.3 32.3 30.4 27.4 16.4 20.2 31.4 63.6 33.2 25.9 34.9 40.0 30.9 22.3 32.6 22.4 37.4 38.9 28.2 28.2 29.2 33.8 21.4 32.2 21.9 43.6 34.6 38.8 24.2 22.4 16.7 24.0 31.9 22.7 32.8 21.4 18.7 27.7 31.6 35.2 56.8 22.4 25.6 29.8 41.8 86.6 27.8 24.6 26.8 68.7 28.4 50.1 37.2 31.3 35.1 37.9 33.0 35.2 26.1 42.9 30.9 28.4 44.9 36.3 44.1 16.4 44.5 33.0 12.4 13.5 15.4 13.9 12.9 12.0 12.0 11.8 11.3 11.6 13.0 14.3 11.3 9.6 9.7 11.4 17.8 16.8 11.2 13.2 22.2 9.7 7.5 6.3 3.5 17.2 12.3 12.9 8.4 17.9 20.7 14.8 13.7 15.1 67.9 12.2 9.2 13.3 16.2 20.2 7.1 20.7 14.4 7.8 9.2 12.6 8.2 11.9 13.2 10.8 13.3 15.2 7.2 11.2 6.1 6.2 7.8 12.3 11.1 10.4 7.2 4.7 12.3 7.7 19.6 6.0 6.5 25.3 8.4 9.8 18.6 7.6 11.4 9.3 14.1 6.9 0.0 10.1 10.6 43.6 19.4 14.2 16.8 19.4 17.4 11.6 10.7 10.9 TPST2 TANGO13B ENSG00000128294 "Tyrosylprotein sulfotransferase 2" O60704 22 26521996-26596717 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 398.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 171.0;NK-cells: 263.7;Plasma cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 158.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021054 Enhanced "Intracellular and membrane" NA NA 88000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 25: Pancreas - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA021054: AB_1858221" "unprognostic (2.24e-1)" "unprognostic (1.70e-1)" "unprognostic (1.74e-2)" "prognostic favorable (8.08e-5)" "unprognostic (8.88e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-2)" "unprognostic (3.38e-1)" "unprognostic (2.70e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (2.34e-6)" "unprognostic (9.68e-2)" "unprognostic (9.21e-3)" "unprognostic (5.62e-2)" "unprognostic (2.01e-1)" 24.4 31.0 24.4 15.2 20.8 23.1 21.8 19.1 29.9 17.4 26.9 11.5 13.6 18.0 111.6 18.7 17.0 12.2 27.5 23.4 22.9 24.9 74.9 45.7 19.1 22.0 24.2 9.2 398.8 5.3 9.9 41.8 20.8 16.0 8.8 3.3 10.9 17.8 38.5 18.4 13.4 12.1 23.1 36.4 11.7 20.6 34.2 10.7 38.8 22.6 17.0 17.1 17.3 20.7 12.8 9.1 11.7 6.0 24.4 18.7 16.4 27.9 49.9 22.2 20.3 6.2 6.5 21.4 7.3 50.4 11.6 19.5 8.8 19.2 12.7 8.8 16.9 51.8 5.6 13.1 10.2 6.0 158.7 20.1 30.3 22.5 7.7 22.5 41.6 9.6 52.6 65.2 17.2 14.3 24.3 40.7 15.4 10.0 9.1 22.5 15.8 60.2 6.7 14.3 8.8 6.1 12.9 11.2 16.0 17.0 5.2 24.7 33.2 27.3 61.2 22.5 27.3 20.9 31.5 20.6 20.7 23.1 25.3 490.4 77.0 111.9 249.2 86.3 70.5 23.6 57.0 187.2 48.3 25.6 27.8 163.6 163.0 354.9 94.3 115.3 71.9 240.7 24.4 20.8 19.1 29.9 23.4 22.9 22.0 24.2 20.8 23.1 34.2 20.7 37.3 16.0 12.6 13.7 30.8 38.1 82.5 29.9 14.2 9.0 10.8 13.1 15.5 47.1 14.4 22.0 6.2 171.0 120.8 6.7 27.4 12.9 15.2 31.1 14.8 66.1 0.0 64.6 23.4 65.1 49.8 10.7 5.1 39.5 53.7 13.9 113.6 79.3 123.9 6.7 20.3 9.3 12.2 55.9 48.6 4.5 5.3 70.1 28.4 47.8 32.4 1.9 263.7 5.0 1.9 53.1 8.7 4.1 183.7 36.4 16.5 7.6 18.6 5.3 6.6 9.9 15.3 2.9 13.2 15.1 35.9 143.0 64.4 42.0 11.8 83.7 CRYBB1 ENSG00000100122 "Crystallin beta B1" P53674 22 26599278-26618027 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 9.6" "Cell type enriched" "Detected in some" 21 "Hofbauer cells: 82.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 10.3;non-classical monocyte: 7.5" "Lineage enriched" "Detected in many" 7 "monocytes: 10.3" "Group enriched" "Detected in some" 5 "Karpas-707: 43.3;RPMI-8226: 82.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA003448, CAB010058" Supported NA NA 89000 "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" "CAB010058: AB_668166, HPA003448: AB_2732396" "unprognostic (1.31e-1)" "unprognostic (5.56e-3)" "unprognostic (1.39e-2)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (2.18e-1)" "unprognostic (7.89e-3)" "unprognostic (1.51e-1)" "unprognostic (9.51e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-4)" "unprognostic (2.62e-2)" "unprognostic (1.23e-2)" "unprognostic (3.22e-1)" "unprognostic (1.76e-2)" 1.3 1.6 1.5 0.9 1.6 0.6 0.6 1.6 2.4 0.6 1.3 0.5 0.4 0.3 9.6 0.4 0.4 1.2 0.4 1.6 1.6 0.2 0.4 0.5 1.2 1.9 1.8 0.2 0.2 0.3 0.5 3.3 2.3 0.2 0.4 0.0 0.4 0.2 0.1 0.1 0.4 0.9 1.9 1.6 0.3 0.3 2.2 0.4 0.2 0.2 0.5 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 1.5 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 43.3 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 0.0 82.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 4.6 0.0 0.2 0.5 0.0 0.0 0.7 0.2 1.8 0.0 2.2 0.0 0.0 1.0 0.0 0.0 10.3 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.5 7.5 0.0 0.0 0.6 1.5 1.6 1.6 2.4 1.6 1.6 1.9 1.8 2.3 1.9 2.2 2.1 0.1 0.0 0.0 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.9 0.0 0.5 0.2 0.0 0.1 1.3 0.0 0.0 0.2 82.6 0.0 0.2 0.0 0.0 3.5 0.8 0.6 0.0 2.8 1.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.2 0.0 0.0 CRYBA4 ENSG00000196431 "Crystallin beta A4" P53673 22 26621963-26630669 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.5;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 3.3;NK-cells: 1.0;Spermatogonia: 3.2" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.0;testis cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HEL: 7.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebral cortex: 4.3;hippocampal formation: 4.0" HPA071178 Supported NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA071178: AB_2686354" "unprognostic (6.69e-2)" "unprognostic (3.94e-3)" "unprognostic (5.61e-5)" "unprognostic (1.74e-2)" "unprognostic (5.57e-2)" "unprognostic (2.32e-2)" "unprognostic (2.71e-1)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-6)" "unprognostic (2.86e-1)" "unprognostic (1.20e-6)" "unprognostic (1.87e-2)" "unprognostic (7.23e-2)" "unprognostic (7.71e-2)" "unprognostic (3.70e-1)" 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.2 0.0 0.0 0.3 0.1 0.0 0.5 0.1 MN1 "MGCR, MGCR1, MGCR1-PEN" ENSG00000169184 "MN1 proto-oncogene, transcriptional regulator" Q10571 22 27748277-27801756 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.7;skeletal muscle: 61.6;tongue: 42.6" "Cell type enhanced" "Detected in many" "Astrocytes: 12.1;Early spermatids: 22.3;Fibroblasts: 13.9;Langerhans cells: 11.2;Late spermatids: 15.2;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 30.7;HeLa: 12.7;hTERT-RPE1: 13.7;RH-30: 12.4;TIME: 20.1;U-2 OS: 16.3;U-2197: 17.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003072 Approved Approved Nucleoplasm NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA003072: AB_1079399" "unprognostic (5.64e-2)" "unprognostic (2.48e-2)" "unprognostic (1.09e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-2)" "unprognostic (2.52e-2)" "unprognostic (7.01e-2)" "unprognostic (3.03e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (4.00e-2)" "unprognostic (7.33e-2)" "unprognostic (5.13e-7)" "unprognostic (3.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.28e-3)" "unprognostic (2.21e-4)" 4.1 0.8 6.0 1.6 20.7 1.3 2.3 6.4 9.5 2.2 0.5 6.1 0.8 2.7 1.0 3.6 4.3 3.0 6.7 1.9 5.3 0.9 0.4 3.3 0.1 4.3 13.0 9.6 0.7 0.1 2.7 1.3 6.8 2.3 0.9 1.8 2.7 1.2 61.6 1.8 2.1 2.5 2.1 0.4 4.0 0.8 8.5 0.3 2.1 42.6 0.7 3.3 3.5 3.1 0.0 1.5 30.7 0.9 0.6 1.3 0.0 0.7 1.1 0.0 0.0 0.0 0.1 0.0 3.1 5.7 1.3 2.7 1.5 1.8 0.0 0.0 0.8 0.0 12.7 0.0 0.7 0.0 0.3 0.1 3.5 0.7 3.0 13.7 0.3 0.0 0.0 0.2 1.0 0.0 0.0 0.4 4.0 0.0 2.8 5.3 12.4 0.0 0.4 0.0 0.1 0.4 2.7 0.0 0.0 7.5 0.3 0.1 20.1 1.0 16.3 17.9 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.0 20.7 6.4 9.5 1.9 5.3 4.3 13.0 6.8 2.1 8.5 3.1 2.1 3.2 2.3 12.1 0.3 4.2 0.1 2.6 3.4 8.4 1.8 0.6 7.4 1.5 0.7 0.0 0.0 0.1 0.2 0.0 0.0 1.4 22.3 1.4 1.0 6.6 0.0 0.0 6.4 1.0 0.1 13.9 0.5 3.1 0.0 0.6 2.5 0.6 0.3 0.0 9.6 0.0 2.0 1.4 11.2 15.2 5.0 2.7 0.0 2.8 0.3 3.9 0.0 13.0 4.3 2.8 0.0 10.1 1.3 0.2 0.0 0.1 0.1 0.7 0.0 2.4 2.3 0.4 1.1 1.9 2.7 0.0 0.3 0.4 0.0 0.2 PITPNB VIB1B ENSG00000180957 "Phosphatidylinositol transfer protein beta" P48739 22 27851669-27920134 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 300000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (9.29e-2)" "unprognostic (1.64e-1)" "unprognostic (4.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.34e-1)" "unprognostic (7.52e-3)" "unprognostic (4.78e-2)" "unprognostic (8.22e-3)" "unprognostic (1.56e-3)" "unprognostic (2.42e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (6.28e-2)" "unprognostic (2.89e-2)" "unprognostic (1.64e-1)" 42.2 27.1 27.9 33.3 30.4 21.6 33.0 30.9 34.1 31.7 22.6 53.1 21.9 31.5 28.6 52.5 29.3 35.4 35.8 32.2 31.6 25.2 56.9 32.1 34.6 29.5 31.8 30.0 28.3 24.0 22.5 49.2 30.5 27.5 30.1 18.1 24.7 37.0 21.3 30.3 28.1 44.2 29.1 27.7 35.3 19.4 31.9 33.4 24.8 21.7 41.1 54.2 36.6 30.5 94.1 39.8 71.5 53.8 62.3 74.7 54.5 88.8 77.4 95.5 91.7 63.4 43.1 64.7 46.0 86.0 70.5 96.6 103.0 88.7 133.2 111.1 97.4 66.1 62.0 58.5 66.9 152.5 102.6 67.2 85.0 115.7 119.6 62.9 94.4 44.8 95.3 130.5 88.5 50.0 64.9 74.7 54.4 97.8 52.1 81.6 112.9 95.6 79.1 87.6 83.6 104.7 60.8 72.7 75.7 75.9 39.4 53.7 93.2 94.9 138.9 72.9 94.2 53.0 66.7 125.2 81.6 74.1 82.2 36.0 18.6 18.6 30.9 21.7 34.0 35.2 29.7 32.3 24.9 30.9 28.4 28.0 16.7 27.4 21.2 22.2 40.8 26.0 27.9 30.4 30.9 34.1 32.2 31.6 29.5 31.8 30.5 29.1 31.9 30.5 97.0 28.9 32.4 57.8 44.3 96.0 128.9 40.8 65.4 24.1 37.4 33.4 57.8 35.8 48.4 31.3 14.6 39.7 45.9 26.1 37.2 49.0 21.4 55.4 72.5 62.4 25.2 15.8 51.8 50.2 52.3 65.9 32.6 79.8 21.5 37.0 30.7 45.8 27.3 32.0 45.7 26.7 24.4 23.6 42.2 6.9 32.0 35.1 26.6 68.4 55.6 17.4 48.4 60.8 67.0 66.7 21.1 48.2 54.2 97.5 17.2 29.6 22.8 16.1 26.3 57.9 76.7 44.0 35.4 60.9 82.1 48.6 42.3 46.9 24.0 112.9 TTC28 KIAA1043 ENSG00000100154 "Tetratricopeptide repeat domain 28" Q96AY4 22 27978014-28679865 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 291.5;Excitatory neurons: 169.6;Inhibitory neurons: 289.8;Microglial cells: 332.6;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001080 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Microtubules, Cytokinetic bridge, Mitotic spindle" Cytosol "HPA001080: " "unprognostic (9.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-1)" "unprognostic (8.55e-3)" "unprognostic (4.83e-2)" "unprognostic (5.20e-2)" "unprognostic (2.25e-1)" "prognostic favorable (4.30e-4)" "unprognostic (3.91e-2)" "unprognostic (1.18e-2)" "unprognostic (5.40e-2)" "unprognostic (5.10e-2)" "prognostic favorable (5.65e-5)" "unprognostic (5.54e-3)" "unprognostic (1.85e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (4.36e-1)" 7.2 4.6 4.3 2.9 3.0 0.8 6.3 0.4 3.4 8.8 2.6 6.9 3.1 10.2 9.8 5.2 8.7 6.4 4.9 3.9 1.8 4.9 3.5 7.2 2.0 2.4 2.0 16.8 5.0 3.8 3.8 8.8 1.4 5.1 2.9 3.4 6.8 6.9 5.4 3.0 3.8 8.5 1.8 3.5 4.8 8.1 2.1 2.7 6.8 5.1 1.4 6.3 5.0 2.1 0.0 6.8 17.1 7.4 10.0 14.8 0.3 5.1 9.4 7.1 6.1 0.5 0.0 0.1 6.9 14.9 2.3 1.0 11.1 0.3 3.8 0.7 7.5 1.1 8.6 6.5 4.5 0.2 6.8 14.9 0.3 4.6 3.2 4.8 13.0 4.5 4.5 0.6 1.6 2.5 0.1 0.6 3.1 0.0 4.3 7.0 4.3 0.1 3.3 0.2 4.8 10.6 7.1 0.2 4.5 4.7 3.5 0.6 12.2 8.4 4.0 5.5 3.8 2.2 0.2 0.1 3.0 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 4.3 3.0 0.4 3.4 3.9 1.8 2.4 2.0 1.4 1.8 2.1 2.1 29.4 3.2 12.5 291.5 3.2 6.0 5.8 1.7 11.4 34.1 8.7 8.0 9.7 8.6 1.6 12.9 18.8 6.0 2.3 2.1 0.0 6.2 10.8 7.9 28.9 30.9 9.0 7.0 169.6 6.0 1.5 27.3 4.1 12.4 1.3 32.3 36.8 15.3 3.7 28.6 289.8 5.8 0.0 9.4 7.2 9.1 31.4 4.3 10.6 332.6 0.7 11.5 5.2 318.7 116.3 3.9 4.4 45.5 3.1 5.0 4.8 18.6 1.9 24.9 13.1 27.2 19.7 23.8 11.6 6.7 3.8 2.5 3.2 27.4 6.9 4.0 CHEK2 "bA444G7, CDS1, CHK2, HuCds1, PP1425, RAD53" ENSG00000183765 "Checkpoint kinase 2" O96017 22 28687743-28742422 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatogonia: 31.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001878, CAB002030" Enhanced Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus" "CAB002030: AB_563660, HPA001878: AB_1078514" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (5.83e-2)" "unprognostic (2.93e-2)" "unprognostic (2.42e-1)" "unprognostic (3.83e-2)" "unprognostic (1.49e-3)" "unprognostic (5.08e-3)" "unprognostic (3.33e-3)" "unprognostic (9.62e-3)" "unprognostic (1.28e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (7.80e-9)" "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (7.27e-2)" "unprognostic (6.79e-3)" 4.5 6.2 2.4 8.8 2.5 15.4 5.8 2.4 3.7 5.0 2.8 8.8 6.3 4.1 7.3 7.2 3.7 4.7 4.2 2.3 2.8 4.5 6.3 4.4 12.1 2.6 2.6 8.2 2.3 1.3 2.7 7.8 2.8 4.1 10.9 0.4 3.2 3.8 1.3 6.7 7.0 4.8 2.6 6.7 4.1 8.5 2.8 9.4 3.3 1.1 12.0 6.8 5.0 2.9 30.7 9.7 31.1 32.4 10.1 42.7 18.7 15.2 19.9 18.7 27.8 29.1 21.8 36.3 13.0 11.5 21.6 32.1 42.7 29.0 25.0 24.6 31.2 45.3 25.5 46.2 9.4 33.4 38.0 18.6 13.5 25.0 23.0 14.1 25.4 29.4 30.5 33.9 19.8 39.2 24.6 61.5 40.6 41.3 21.6 52.6 18.2 42.7 17.1 11.2 17.8 9.7 16.7 31.4 17.4 22.8 22.6 32.2 7.8 17.1 19.4 14.3 9.1 21.8 28.3 65.4 17.1 34.9 21.0 9.9 4.0 1.2 1.1 8.1 2.4 11.9 2.1 2.1 8.2 7.8 4.0 2.6 0.6 3.4 4.1 6.1 2.8 3.6 2.4 2.5 2.4 3.7 2.3 2.8 2.6 2.6 2.8 2.6 2.8 2.9 2.3 9.6 4.8 2.9 5.5 6.4 5.3 8.3 8.6 1.1 3.2 3.9 1.8 0.0 5.0 1.8 0.0 15.4 1.1 3.8 0.0 1.8 7.0 2.9 10.1 3.0 1.2 11.2 2.9 1.4 13.6 12.4 5.1 7.0 3.8 7.4 2.5 1.3 9.7 0.0 1.2 5.3 8.2 2.4 8.5 1.2 6.2 5.1 1.8 2.8 3.9 0.8 6.2 0.0 1.0 1.0 4.7 4.5 11.4 2.7 3.0 3.9 2.9 1.1 0.0 10.2 3.0 6.7 31.2 8.3 2.3 3.4 3.3 5.7 10.0 4.5 HSCB "DNAJC20, HSC20, Jac1" ENSG00000100209 "HscB mitochondrial iron-sulfur cluster cochaperone" Q8IWL3 22 28742039-28757515 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018447, HPA031518" Uncertain Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria, Cytosol" "HPA018447: AB_1853867, HPA031518: AB_2673919" "unprognostic (8.19e-3)" "unprognostic (6.48e-2)" "unprognostic (9.62e-3)" "prognostic favorable (3.78e-4)" "unprognostic (3.30e-1)" "unprognostic (7.02e-2)" "unprognostic (1.15e-1)" "unprognostic (2.53e-2)" "unprognostic (5.83e-2)" "unprognostic (7.38e-3)" "unprognostic (4.44e-1)" "unprognostic (2.81e-1)" "unprognostic (1.54e-3)" "unprognostic (2.19e-1)" "unprognostic (3.39e-1)" "unprognostic (2.12e-1)" "prognostic favorable (8.38e-4)" 8.6 15.3 5.1 6.0 4.9 3.2 9.8 5.3 6.9 12.3 4.7 11.1 8.6 8.0 5.1 7.9 9.3 7.1 8.4 4.8 5.1 11.0 22.0 6.2 11.0 5.6 4.8 12.0 12.5 5.3 7.3 4.5 5.7 10.7 4.5 1.0 18.8 6.2 11.6 7.9 7.3 4.6 5.0 9.0 11.5 4.1 5.4 4.3 8.0 8.1 4.9 10.7 9.0 5.8 13.8 8.5 3.4 5.5 6.3 16.0 6.5 9.9 13.8 14.2 8.8 3.8 4.8 15.1 4.6 5.6 3.4 9.5 6.9 6.3 6.9 14.6 27.2 5.3 5.8 10.7 13.4 9.7 7.7 10.9 13.8 8.0 12.6 7.5 11.0 4.2 8.2 13.1 5.7 20.1 4.3 8.9 8.4 15.0 20.9 8.6 10.8 17.2 15.9 3.9 11.8 10.8 5.4 20.5 25.9 2.9 8.6 5.9 6.0 19.3 10.2 18.6 9.2 18.2 15.9 13.5 13.5 7.1 13.2 10.1 7.8 4.1 6.1 15.2 7.3 13.0 6.2 7.2 11.5 9.6 6.6 8.3 0.4 11.1 12.0 6.0 4.9 5.9 5.1 4.9 5.3 6.9 4.8 5.1 5.6 4.8 5.7 5.0 5.4 5.8 21.4 22.4 19.6 14.4 22.8 11.6 22.2 23.3 40.5 5.5 29.4 37.7 7.8 18.6 23.9 20.2 6.2 16.0 16.7 9.0 29.4 25.0 5.5 12.7 23.3 18.4 19.8 12.6 10.0 28.0 13.5 21.4 11.7 21.6 23.4 17.2 20.3 36.3 27.9 5.0 11.2 14.6 16.2 19.0 14.9 4.3 18.6 19.2 14.2 9.4 22.6 17.4 41.2 16.1 14.2 21.2 11.3 11.7 34.1 20.5 20.2 58.1 24.1 8.1 6.6 19.1 21.9 15.1 16.7 19.8 15.6 13.3 15.9 27.1 21.2 17.2 CCDC117 FLJ33814 ENSG00000159873 "Coiled-coil domain containing 117" Q8IWD4 22 28772674-28789301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 104.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000826 Uncertain Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Microtubules, Cytosol" "HPA000826: AB_1078417" "unprognostic (1.71e-1)" "unprognostic (2.04e-2)" "unprognostic (1.61e-3)" "unprognostic (9.07e-2)" "unprognostic (3.84e-2)" "unprognostic (1.26e-1)" "unprognostic (1.62e-1)" "unprognostic (1.35e-2)" "unprognostic (8.43e-2)" "unprognostic (7.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-3)" "unprognostic (8.25e-2)" 9.5 10.2 11.8 12.7 12.7 21.8 11.9 15.7 22.8 14.2 13.4 11.2 11.8 11.5 8.0 8.2 9.1 9.5 7.9 11.6 12.5 9.8 24.2 9.4 18.2 11.6 11.8 12.5 9.4 12.6 6.7 19.1 11.5 9.8 11.2 10.6 18.3 9.3 16.9 8.2 9.4 9.7 11.8 12.6 10.0 36.6 13.1 17.9 10.9 20.7 20.3 10.6 7.5 17.6 19.9 16.0 32.2 31.7 20.6 18.0 25.5 19.7 23.9 33.4 29.2 24.6 9.4 61.7 8.6 18.0 14.2 20.2 47.8 7.8 31.6 33.6 31.4 25.2 17.3 36.6 14.1 40.6 30.9 12.2 16.8 19.3 11.9 14.9 23.5 20.0 36.0 26.6 15.2 25.6 24.1 32.8 26.4 35.3 7.7 48.1 50.8 27.0 14.9 7.6 12.3 16.4 30.4 28.0 12.7 38.0 34.9 17.4 13.7 41.7 28.3 13.3 15.3 61.7 68.9 51.2 14.6 21.9 18.1 13.5 14.6 15.3 10.0 13.2 10.2 10.0 8.3 9.8 14.6 12.4 14.5 11.8 6.7 25.3 12.9 12.7 11.6 14.9 11.8 12.7 15.7 22.8 11.6 12.5 11.6 11.8 11.5 11.8 13.1 17.6 11.1 22.4 14.3 4.2 18.3 10.6 14.4 4.3 6.2 7.7 21.9 14.2 10.4 15.7 8.5 14.7 14.6 16.5 20.4 13.2 7.9 9.9 104.0 20.7 32.5 15.5 20.4 17.4 6.6 10.0 17.8 14.3 6.6 31.0 17.2 11.9 10.8 42.3 9.3 3.3 7.1 12.3 4.1 18.9 19.0 38.2 12.8 15.4 17.8 7.5 14.7 6.2 21.6 4.5 12.8 9.7 8.9 7.9 26.4 22.6 9.0 12.5 13.8 15.2 0.0 9.6 16.1 49.5 48.5 9.5 10.9 24.6 14.7 9.0 12.4 22.3 XBP1 XBP2 ENSG00000100219 "X-box binding protein 1" P17861 22 28794555-28800597 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Angiogenesis, Apoptosis, Autophagy, Differentiation, Lipid biosynthesis, Lipid metabolism, Myogenesis, Protein transport, Stress response, Transcription, Transcription regulation, Transport, Unfolded protein response" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 1159.0" "Cell type enhanced" "Detected in all" "Breast glandular cells: 1756.7;Plasma cells: 2344.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 960.5;SK-BR-3: 870.0;T-47d: 1012.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" 100.3 103.7 23.8 150.1 25.9 247.2 720.6 26.8 27.7 369.7 46.8 203.6 163.7 94.2 150.5 85.2 126.5 120.2 75.8 22.5 32.2 87.7 687.3 151.8 138.3 33.3 33.2 67.5 1159.0 195.1 87.7 107.9 29.0 228.8 196.5 21.1 849.4 152.1 90.1 72.2 140.3 105.5 30.8 213.2 259.9 22.2 33.0 148.2 168.9 48.7 307.8 250.4 52.2 30.8 77.1 50.8 71.4 111.0 132.2 144.2 181.1 130.9 223.2 128.4 168.8 82.5 104.4 290.2 63.0 121.8 75.3 104.5 134.2 64.4 110.4 130.0 84.9 88.3 42.6 356.2 285.9 166.1 80.8 90.7 378.2 85.2 363.7 115.9 104.1 35.0 79.5 355.0 78.6 960.5 23.3 157.0 49.7 594.6 79.0 168.6 78.5 401.5 118.4 105.4 94.7 90.7 79.0 870.0 358.6 94.8 1012.9 188.5 59.8 73.3 69.8 78.5 47.3 598.8 456.8 174.8 98.0 210.0 112.3 185.0 27.1 23.5 73.3 14.1 95.2 38.0 52.4 76.5 23.5 43.8 52.9 43.2 2.1 88.5 10.1 75.0 20.5 38.5 23.8 25.9 26.8 27.7 22.5 32.2 33.3 33.2 29.0 30.8 33.0 30.8 116.4 86.6 195.6 3.6 379.0 210.6 410.2 192.2 47.3 25.4 1756.7 829.4 46.2 205.9 390.1 138.0 131.3 112.8 298.6 171.2 80.3 240.6 30.2 160.1 147.8 107.0 189.7 68.6 8.5 633.3 335.4 220.0 208.0 293.6 99.7 55.1 93.1 654.5 267.9 15.2 11.4 633.0 225.9 130.0 281.5 22.7 95.7 172.3 355.8 18.7 95.0 18.6 385.2 8.0 7.3 328.4 190.5 64.7 2344.9 381.9 247.0 73.2 168.9 53.2 13.1 144.4 179.3 36.8 32.5 86.2 202.0 349.7 206.1 34.8 260.0 355.3 ZNRF3 "BK747E2.3, FLJ22057, KIAA1133, RNF203" ENSG00000183579 "Zinc and ring finger 3" Q9ULT6 22 28883572-29057488 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway, Wnt signaling pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Astrocytes: 504.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 46.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036702, HPA036703" Uncertain Uncertain "Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "Golgi apparatus" "HPA036702: , HPA036703: AB_10672227" "unprognostic (1.07e-1)" "unprognostic (2.13e-3)" "unprognostic (7.48e-3)" "unprognostic (5.72e-2)" "unprognostic (6.81e-2)" "unprognostic (1.36e-1)" "unprognostic (2.22e-2)" "unprognostic (1.75e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (5.18e-2)" "unprognostic (3.94e-1)" "unprognostic (9.55e-5)" "unprognostic (6.49e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.55e-2)" 2.8 7.1 11.3 1.3 11.2 0.3 2.6 8.1 13.8 4.4 1.0 3.9 3.0 5.1 13.4 3.4 4.8 2.1 2.6 12.1 5.5 8.2 6.6 4.3 0.5 13.2 9.2 5.9 3.3 8.7 2.7 5.0 4.2 7.2 3.4 1.1 7.5 7.7 3.8 5.3 2.7 4.6 5.1 1.2 4.4 5.0 13.6 1.3 4.1 1.9 0.6 3.2 3.3 6.2 5.8 13.7 12.5 3.5 2.3 2.6 23.7 3.5 1.7 2.7 2.6 20.8 3.2 0.1 5.4 1.8 4.9 9.8 8.7 5.5 3.3 7.8 8.9 2.3 2.5 46.1 2.0 6.9 2.3 2.7 5.0 4.3 4.3 2.3 2.4 4.1 5.0 3.2 3.9 5.6 0.2 3.5 4.6 7.3 5.4 6.9 8.2 5.3 11.6 8.5 20.6 7.6 6.2 6.1 3.5 3.8 4.1 3.1 2.3 10.3 8.8 8.2 5.8 4.3 6.3 8.1 4.4 3.9 5.5 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 11.3 11.2 8.1 13.8 12.1 5.5 13.2 9.2 4.2 5.1 13.6 6.2 4.2 12.8 23.6 504.1 0.3 12.6 5.2 4.9 15.9 3.7 5.7 9.5 7.5 8.6 5.3 12.9 0.0 28.1 0.5 2.1 1.9 5.0 12.7 8.0 8.0 5.8 8.4 4.0 62.9 2.5 2.5 5.8 5.6 15.5 0.0 5.4 2.2 17.6 3.5 1.7 37.4 9.4 0.0 1.0 3.1 15.0 10.8 0.8 0.0 82.4 0.0 6.0 0.0 54.8 34.4 3.7 2.1 12.8 0.6 9.6 2.4 11.6 4.9 3.9 0.0 16.0 6.6 4.6 3.2 7.8 7.5 7.7 0.7 14.5 12.9 2.8 C22orf31 "bK747E2.1, HS747E2A" ENSG00000100249 "Chromosome 22 open reading frame 31" O95567 22 29058672-29061844 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "parathyroid gland: 3.0;testis: 8.7" "Group enriched" "Detected in some" 6 "Early spermatids: 70.0;Late spermatids: 43.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000604, HPA068522" Uncertain Approved "Nuclear membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear membrane" Cytosol "HPA000604: AB_1079086, HPA068522: " 0.1 0.3 1.7 0.0 2.3 0.0 0.3 2.3 2.7 0.3 1.3 0.3 0.2 0.3 0.9 0.3 0.3 0.0 0.1 1.9 1.5 0.4 0.0 0.2 0.0 1.5 1.6 0.6 0.0 3.0 0.4 0.0 1.5 0.2 0.2 0.3 0.4 0.1 0.2 0.4 0.3 0.1 1.2 0.1 0.4 8.7 1.7 1.0 0.2 0.2 0.1 0.3 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.3 2.3 2.7 1.9 1.5 1.5 1.6 1.5 1.2 1.7 1.6 0.0 0.0 0.0 8.5 0.0 0.1 0.2 0.2 0.0 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 70.0 0.3 1.6 0.1 0.0 0.0 0.5 0.0 0.0 1.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 43.3 0.9 0.0 1.8 1.0 0.0 3.3 0.0 0.5 0.1 0.0 0.0 0.7 0.0 0.1 0.1 0.2 0.0 0.0 0.0 3.7 0.2 1.0 0.5 0.2 0.9 0.0 0.1 1.0 0.1 0.1 KREMEN1 "KREMEN, KRM1" ENSG00000183762 "Kringle containing transmembrane protein 1" Q96MU8 22 29073035-29168333 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 59.1;Skeletal myocytes: 82.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.3;neutrophil: 4.6" "Lineage enriched" "Detected in single" 7 "granulocytes: 4.6" "Cell line enhanced" "Detected in many" "RH-30: 34.7;U-2197: 59.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058513 Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No 1100000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies, Cytosol" "HPA058513: AB_2683739" 7.3 13.5 10.3 9.5 22.3 4.1 7.6 7.4 10.8 9.1 5.6 13.1 6.6 6.7 8.7 37.2 10.9 4.0 22.7 12.7 7.6 9.0 2.4 11.9 2.9 8.2 9.8 22.2 4.6 48.2 6.5 6.1 8.0 9.1 11.3 4.0 28.3 9.8 28.7 36.3 11.1 6.2 5.6 9.1 9.4 12.5 12.9 22.4 9.5 42.6 16.4 9.2 13.7 8.3 5.2 3.6 11.8 6.2 3.9 11.9 9.9 1.4 12.0 3.8 5.7 16.5 2.4 0.1 4.5 5.6 9.6 24.7 24.6 9.9 4.1 6.2 15.5 1.4 1.7 15.6 4.1 0.1 1.3 11.4 19.7 4.3 2.4 1.6 0.6 10.1 5.4 0.3 4.8 4.4 0.1 1.7 0.5 34.0 2.5 0.8 34.7 0.3 4.1 9.7 23.6 13.1 14.2 5.0 18.3 3.9 18.5 0.9 0.4 15.7 4.8 59.3 1.7 1.2 0.4 0.2 10.0 2.2 18.5 1.3 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 4.6 0.3 0.2 0.6 0.1 0.1 10.3 22.3 7.4 10.8 12.7 7.6 8.2 9.8 8.0 5.6 12.9 8.3 2.0 16.0 18.4 59.1 0.3 15.3 14.0 14.1 7.4 4.4 5.7 6.1 23.9 14.3 18.3 7.3 0.0 15.5 0.3 3.9 1.9 5.4 3.2 6.2 19.7 3.9 0.0 17.2 10.3 4.2 1.8 24.4 8.6 8.0 19.0 5.9 5.3 2.6 2.6 0.0 2.7 19.4 4.1 24.1 6.8 10.8 17.7 2.5 0.0 15.9 2.7 22.2 2.1 10.6 6.3 3.0 9.5 10.5 0.1 10.9 2.2 4.7 18.4 3.4 13.1 82.2 7.9 8.1 6.0 26.3 19.5 5.3 2.3 33.5 10.2 10.5 EMID1 "EMI5, EMU1, hEmu1" ENSG00000186998 "EMI domain containing 1" Q96A84 22 29205896-29259597 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.5;lymphoid tissue: 54.8" "Cell type enhanced" "Detected in many" "Astrocytes: 92.1;Granulosa cells: 32.7;Oligodendrocyte precursor cells: 51.8;Theca cells: 151.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 23.1;glioma: 7.8;ovarian cancer: 10.9;thyroid cancer: 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HEL: 28.8;NB-4: 102.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000592 Uncertain "Secreted in other tissues" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "HPA000592: AB_1078737" "unprognostic (2.20e-2)" "unprognostic (1.13e-1)" "unprognostic (1.28e-2)" "unprognostic (7.80e-3)" "unprognostic (2.40e-2)" "unprognostic (1.42e-1)" "unprognostic (3.46e-1)" "unprognostic (6.25e-3)" "unprognostic (3.75e-2)" "unprognostic (2.33e-1)" "unprognostic (5.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.36e-3)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "unprognostic (3.09e-2)" "unprognostic (1.08e-1)" 2.6 29.0 34.5 4.2 35.0 14.8 2.5 27.7 49.5 6.5 24.4 5.7 5.1 10.0 1.7 1.3 10.4 4.8 2.3 36.8 29.4 15.0 3.3 13.0 7.5 30.1 30.4 7.0 14.0 12.4 2.0 4.9 28.3 6.1 3.4 0.3 3.6 3.9 0.8 6.3 8.3 2.3 27.0 54.8 7.7 2.3 27.8 4.8 13.2 0.3 2.3 4.9 2.2 32.4 0.0 0.2 4.9 10.5 0.0 0.0 0.7 0.0 0.0 0.4 0.3 5.7 0.7 0.0 4.7 0.1 0.0 0.0 2.5 0.1 0.0 11.5 8.6 28.8 0.1 1.1 0.7 4.1 2.2 0.3 0.2 0.2 0.0 0.0 0.0 6.4 2.5 0.0 0.0 8.0 0.2 102.0 1.1 0.1 0.4 0.0 0.2 11.3 0.0 0.1 13.2 6.3 0.4 0.1 0.2 0.8 4.2 5.4 0.0 0.0 8.0 0.0 0.1 0.5 0.0 0.0 0.0 14.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 34.5 35.0 27.7 49.5 36.8 29.4 30.1 30.4 28.3 27.0 27.8 32.4 0.4 0.0 2.5 92.1 0.1 2.8 1.0 0.1 0.0 1.7 5.3 3.9 0.7 4.3 0.6 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.2 10.8 22.6 6.2 0.0 18.5 5.6 1.3 0.1 11.8 0.5 20.0 11.4 32.7 11.4 2.1 0.3 0.0 6.2 0.4 0.0 0.3 5.2 0.5 3.1 0.6 0.0 10.3 0.6 1.1 0.0 51.8 1.0 0.4 0.0 1.9 1.0 1.9 0.1 1.9 0.0 0.4 0.0 17.5 4.0 0.1 1.5 0.0 2.0 0.3 1.1 151.0 0.3 0.4 RHBDD3 "C22orf3, PTAG" ENSG00000100263 "Rhomboid domain containing 3" Q9Y3P4 22 29259872-29268209 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043979 Approved Approved Microtubules NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Microtubules "HPA043979: AB_10960539" "unprognostic (9.38e-2)" "unprognostic (1.19e-2)" "unprognostic (1.22e-1)" "prognostic favorable (2.67e-6)" "unprognostic (1.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.13e-3)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (8.46e-2)" "unprognostic (4.42e-3)" "unprognostic (1.80e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.11e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (3.42e-3)" 7.6 20.7 6.8 2.4 7.7 2.9 6.9 6.7 10.8 7.2 6.4 7.3 4.9 9.0 1.3 8.6 8.6 1.7 10.2 6.4 7.2 10.0 16.8 6.7 1.9 8.7 7.9 8.0 11.8 2.6 14.8 2.1 7.7 13.4 0.6 0.9 7.7 4.4 10.1 6.2 7.1 1.6 7.1 10.7 7.1 22.2 7.3 2.3 10.7 0.5 0.9 7.0 6.0 7.6 4.6 7.7 4.2 12.3 1.3 2.2 23.5 2.9 3.8 3.5 4.4 6.9 10.1 12.6 12.4 2.8 2.1 14.2 2.5 2.3 0.4 16.7 19.9 4.6 6.5 8.6 15.0 10.4 11.5 6.6 6.2 1.5 4.2 2.5 4.8 5.1 5.6 8.3 2.6 9.0 6.8 15.8 19.8 2.9 8.6 11.9 7.8 14.6 1.5 4.6 9.2 4.8 9.9 10.6 12.3 1.0 7.0 9.0 7.0 9.5 4.2 4.0 4.4 20.3 6.6 15.1 4.0 4.6 8.1 0.0 4.6 1.9 2.5 4.1 3.1 1.8 2.4 3.7 4.7 0.9 1.8 2.5 1.4 3.6 3.8 11.2 3.9 2.5 6.8 7.7 6.7 10.8 6.4 7.2 8.7 7.9 7.7 7.1 7.3 7.6 8.4 6.4 7.0 22.2 5.1 6.1 11.7 19.9 5.2 17.2 12.1 9.8 8.4 8.6 16.0 14.7 6.2 44.4 12.8 19.0 0.0 18.6 9.0 19.0 12.8 10.0 8.4 11.2 14.4 19.8 18.7 14.1 21.9 24.6 0.0 21.7 12.8 15.7 25.6 16.8 16.5 15.1 12.2 9.7 5.5 7.4 14.0 7.5 7.2 12.2 7.8 14.5 7.2 11.1 9.9 13.2 16.1 12.0 9.5 16.0 15.9 7.1 12.1 22.9 6.6 9.0 10.2 29.8 26.6 8.6 6.0 38.3 7.4 26.3 17.7 9.6 EWSR1 EWS ENSG00000182944 "EWS RNA binding protein 1" Q01844 22 29268009-29300525 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Calmodulin-binding, Repressor, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004230, HPA051771, HPA062953" Enhanced Enhanced "Nucleoplasm,Nucleoli rim" No No 59000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli rim" "CAB004230: AB_675526, HPA051771: AB_2681602, HPA062953: AB_2684910" "unprognostic (1.96e-1)" "unprognostic (6.39e-3)" "unprognostic (1.32e-1)" "unprognostic (3.93e-2)" "unprognostic (3.59e-1)" "unprognostic (3.15e-2)" "prognostic unfavorable (1.27e-6)" "unprognostic (1.33e-1)" "unprognostic (1.09e-2)" "unprognostic (2.71e-2)" "unprognostic (7.04e-2)" "unprognostic (9.30e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (7.33e-3)" "unprognostic (1.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.50e-3)" 84.8 102.2 63.2 93.2 64.7 172.3 80.3 70.3 69.5 87.9 61.2 90.5 88.0 105.1 61.9 99.0 86.0 56.1 101.7 64.7 63.7 88.0 85.0 76.8 120.1 67.4 64.7 86.8 79.1 98.0 64.1 70.2 63.6 78.4 84.4 111.2 76.5 77.3 140.0 88.0 92.6 86.9 59.7 101.0 84.3 135.5 63.9 183.0 77.2 79.9 126.8 88.1 86.2 71.8 307.7 239.7 327.6 249.1 166.0 136.0 218.2 188.1 301.3 309.9 264.5 270.3 154.5 428.0 114.1 294.3 234.9 238.9 471.5 392.6 313.7 287.5 341.6 323.9 218.8 262.7 246.5 499.5 219.3 211.1 162.5 259.1 413.0 152.2 244.2 201.1 248.3 186.0 233.8 310.6 505.9 185.8 221.1 261.4 182.8 348.1 317.2 253.3 288.0 328.2 261.4 247.7 236.3 258.5 195.9 216.2 170.9 261.0 246.3 184.4 198.2 115.1 272.3 236.2 205.5 387.4 169.9 220.6 224.4 203.9 201.1 182.6 195.2 283.5 199.5 169.4 181.3 194.4 227.5 191.3 175.8 170.9 148.1 216.9 293.0 122.0 244.0 314.2 63.2 64.7 70.3 69.5 64.7 63.7 67.4 64.7 63.6 59.7 63.9 71.8 77.5 102.5 106.8 68.6 130.8 69.5 145.2 153.2 108.1 72.4 63.8 46.6 68.0 87.2 127.2 64.4 75.0 141.0 91.3 92.4 66.5 121.7 165.4 96.3 88.1 88.3 80.9 102.0 55.8 107.6 133.5 85.4 117.2 115.2 121.0 88.5 71.7 71.7 99.3 82.4 60.8 110.9 136.3 69.7 94.0 32.7 61.5 91.9 81.8 47.8 110.9 72.8 122.6 49.8 67.6 116.5 106.4 62.1 156.6 97.4 79.4 72.6 128.9 84.9 52.6 93.1 141.4 209.6 107.5 105.5 58.5 152.4 121.4 84.9 110.2 115.1 GAS2L1 GAR22 ENSG00000185340 "Growth arrest specific 2 like 1" Q99501 22 29306582-29312785 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 84.6;Late spermatids: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 77.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019858 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Cell Junctions" "HPA019858: AB_1849486" "unprognostic (3.66e-1)" "unprognostic (5.22e-2)" "unprognostic (1.38e-1)" "unprognostic (4.95e-3)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-3)" "unprognostic (8.99e-2)" "unprognostic (1.28e-1)" "unprognostic (6.05e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "prognostic favorable (8.44e-4)" "unprognostic (4.23e-2)" "unprognostic (9.04e-2)" "unprognostic (1.32e-1)" "unprognostic (1.19e-2)" 22.6 36.3 46.7 5.5 41.8 6.5 22.4 39.4 58.5 16.2 30.4 25.8 18.1 18.4 5.3 34.3 16.5 4.2 33.5 45.4 37.8 21.0 18.6 19.3 2.3 50.0 43.3 8.9 14.4 6.6 22.1 4.1 42.2 22.2 2.0 4.0 24.7 16.9 6.5 52.8 17.8 4.4 41.8 29.1 27.4 51.3 47.3 1.1 15.6 3.9 1.8 17.6 19.6 37.4 20.4 23.1 3.5 14.5 5.5 5.2 22.6 29.7 8.9 12.3 6.4 10.6 14.2 0.1 13.1 15.9 12.9 60.5 6.0 16.8 2.2 27.6 2.9 26.5 19.9 7.5 7.0 0.2 17.8 5.6 11.5 11.9 4.7 8.9 16.5 26.2 12.8 4.1 9.0 17.2 0.5 14.8 5.3 13.5 51.6 0.6 10.3 1.7 7.5 12.8 1.2 19.0 23.0 30.3 17.0 4.4 30.2 4.1 35.5 77.0 53.0 34.6 30.3 0.3 0.4 0.3 34.1 1.0 19.3 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 46.7 41.8 39.4 58.5 45.4 37.8 50.0 43.3 42.2 41.8 47.3 37.4 34.5 6.4 1.7 28.1 0.4 28.2 7.0 12.3 21.6 3.6 24.0 18.4 5.6 14.3 8.3 1.8 6.2 24.8 0.8 13.4 7.9 12.2 33.8 19.2 9.2 26.2 1.8 19.6 14.8 6.7 14.3 12.0 9.2 10.0 1.3 28.9 84.6 12.0 14.1 13.5 11.4 5.1 20.3 14.5 23.0 89.7 9.6 37.6 12.4 7.5 7.6 5.4 0.0 4.0 4.0 10.2 7.2 11.7 0.2 6.1 41.7 10.1 4.3 20.9 39.5 35.3 23.5 5.4 12.4 27.9 32.4 6.7 2.2 17.8 11.8 4.6 RASL10A RRP22 ENSG00000100276 "RAS like family 10 member A" Q92737 22 29312933-29319679 "Enzymes, Predicted intracellular proteins" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 28.7" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Breast glandular cells: 35.9;Breast myoepithelial cells: 58.3;Excitatory neurons: 35.1;Rod photoreceptor cells: 19.6" "Group enriched" "Detected in some" 4 "glioma: 2.5;testis cancer: 3.4;urothelial cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.6;NB-4: 2.5;U-2 OS: 1.1;U-266/70: 2.7;U-266/84: 1.0" "Group enriched" "Detected in many" 6 "amygdala: 33.7;basal ganglia: 16.7;cerebral cortex: 36.0;hippocampal formation: 26.3;white matter: 15.3" "Group enriched" "Detected in many" 4 "cerebral cortex: 35.6;hippocampal formation: 27.8" HPA056169 Approved NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 24: NB-4 - Immune response" "Cluster 35: Glandular cells - Unknown function" "HPA056169: AB_2683053" "unprognostic (1.94e-1)" "unprognostic (2.51e-4)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (2.94e-2)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (7.99e-2)" "unprognostic (9.42e-2)" "unprognostic (1.61e-2)" "unprognostic (5.00e-4)" "unprognostic (2.44e-1)" "unprognostic (7.00e-4)" "unprognostic (3.12e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-2)" "unprognostic (3.61e-3)" 0.9 1.4 26.6 0.3 23.2 0.1 2.0 6.3 28.7 0.4 5.3 0.7 0.3 0.6 0.1 0.4 0.6 0.1 3.8 24.5 13.4 1.2 0.9 1.2 0.1 9.3 11.6 0.2 0.4 0.1 5.0 0.2 10.4 2.0 0.0 2.6 1.0 0.1 0.7 0.7 1.1 0.0 9.0 1.2 0.5 1.8 13.3 0.1 1.1 0.1 0.1 0.5 0.3 16.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1.6 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.4 0.0 2.5 0.6 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.0 0.5 0.5 0.2 0.1 0.0 1.1 0.0 0.1 2.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 23.2 6.3 28.7 24.5 13.4 9.3 11.6 10.4 9.0 13.3 16.2 3.9 0.0 0.0 17.9 0.4 0.4 0.6 0.0 0.0 6.8 35.9 58.3 1.1 1.5 0.0 0.0 6.2 0.2 1.0 0.7 0.0 0.0 1.3 0.8 0.3 3.1 0.0 0.0 35.1 0.0 4.7 0.5 1.5 1.4 0.0 0.5 7.9 0.5 1.1 0.0 4.4 1.1 0.0 2.6 5.8 0.5 0.3 2.7 0.0 4.7 0.2 3.3 0.0 3.0 3.9 0.1 0.1 0.0 0.3 1.7 0.2 0.1 0.2 19.6 0.0 13.4 0.5 1.5 3.9 0.3 0.6 0.5 0.5 0.6 0.4 0.2 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;retina: 3.0" "Group enriched" "Detected in some" 7 "Early spermatids: 9.1;Hepatic stellate cells: 8.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.5;HMC-1: 2.7;Karpas-707: 3.0;SH-SY5Y: 3.7;SiHa: 1.8;THP-1: 3.5" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (4.54e-1)" "unprognostic (6.63e-8)" "unprognostic (3.14e-3)" "unprognostic (1.89e-1)" 0.1 2.9 2.5 0.2 2.3 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.3 0.1 0.0 1.3 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.5 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.1 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 2.5 2.3 0.0 10.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.4 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 NEFH "NF-H, NFH" ENSG00000100285 "Neurofilament heavy" P12036 22 29480218-29491390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 544.0;prostate: 245.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 20.9;monocytes: 34.6;Prostatic glandular cells: 44.0;Spermatogonia: 29.5;Theca cells: 49.7" "Cancer enriched" "Detected in many" 4 "prostate cancer: 130.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.7" "Lineage enriched" "Detected in single" 5 "monocytes: 4.7" "Cell line enriched" "Detected in many" 5 "SiHa: 182.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 1241.2" "CAB007786, HPA061615" Enhanced NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 35: Glandular cells - Unknown function" "CAB007786: AB_598179, HPA061615: AB_2684568" "prognostic favorable (2.33e-6)" "unprognostic (6.17e-3)" "unprognostic (9.74e-2)" "unprognostic (3.20e-2)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (2.63e-4)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (6.42e-2)" "unprognostic (5.85e-2)" "unprognostic (6.64e-3)" "unprognostic (1.57e-3)" "unprognostic (1.54e-1)" "unprognostic (2.59e-1)" "unprognostic (1.31e-2)" "unprognostic (1.47e-1)" 0.6 21.1 17.7 1.6 18.9 0.6 1.4 143.1 544.0 0.6 0.0 1.4 0.4 0.5 0.7 0.3 0.5 0.4 0.4 7.8 57.3 0.9 0.3 0.4 0.9 494.1 56.2 20.0 0.3 0.9 15.4 0.6 376.1 245.9 0.5 39.6 0.9 0.6 0.3 0.2 0.9 1.0 58.3 1.2 0.6 7.7 172.9 0.7 0.3 0.3 1.0 0.4 1.2 147.3 0.0 0.0 2.4 0.6 0.1 0.3 1.8 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.8 1.9 9.5 0.1 0.0 0.0 0.0 9.0 34.2 0.1 24.2 0.0 1.4 0.2 10.5 3.5 0.0 0.5 0.0 0.0 1.3 0.0 28.0 0.0 11.7 0.0 12.0 1.2 17.4 0.0 0.0 0.1 0.1 1.9 0.0 0.0 1.5 19.5 182.2 0.1 0.0 5.9 0.0 9.9 25.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 1.0 0.0 0.4 2.7 0.8 0.1 0.5 0.4 0.6 0.0 0.1 0.5 0.0 0.2 4.7 0.1 0.2 0.6 17.7 18.9 143.1 544.0 7.8 57.3 494.1 56.2 376.1 58.3 172.9 147.3 0.7 0.0 0.0 3.9 1.0 0.1 1.0 0.1 2.2 3.2 1.4 5.3 0.9 1.5 0.0 1.8 2.1 1.4 1.6 0.5 0.0 0.2 0.4 0.3 7.7 1.0 0.0 5.9 13.6 0.4 1.1 2.4 0.0 0.8 1.3 8.8 0.0 0.0 5.6 8.4 20.9 0.0 0.0 4.2 2.3 1.0 5.9 5.2 1.8 5.6 34.6 3.6 0.0 2.0 2.6 0.3 0.0 3.0 1.7 44.0 0.2 1.0 0.0 9.9 6.6 1.3 2.0 4.4 29.5 3.0 0.1 0.4 1.7 49.7 0.2 0.7 THOC5 "C22orf19, Fmip, fSAP79, KIAA0983, PK1.3" ENSG00000100296 "THO complex 5" Q13769 22 29505879-29555216 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 125.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048402 Supported Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA048402: AB_2680387" "unprognostic (1.16e-1)" "unprognostic (3.05e-1)" "unprognostic (7.77e-2)" "unprognostic (2.27e-2)" "unprognostic (7.20e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.34e-2)" "unprognostic (5.54e-2)" "unprognostic (2.55e-1)" "unprognostic (2.45e-1)" "unprognostic (8.81e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (9.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.24e-1)" "unprognostic (2.97e-1)" 19.3 11.6 5.4 14.2 7.2 19.0 17.2 9.2 10.1 24.4 3.5 37.5 11.4 31.9 13.6 18.5 20.3 17.2 29.2 6.4 7.3 13.4 13.5 14.7 15.3 8.6 7.1 21.5 14.5 14.1 9.3 11.2 9.6 18.2 13.8 11.1 11.9 20.9 43.7 13.8 17.5 29.3 5.0 15.0 20.3 19.8 7.2 14.7 11.3 40.9 15.1 28.7 17.6 9.6 43.0 28.7 25.8 77.5 47.7 38.1 32.7 79.3 46.7 68.8 68.0 46.8 18.8 26.4 30.2 63.4 40.9 37.8 36.5 42.4 67.0 30.5 38.5 43.6 40.8 53.0 32.5 100.1 35.8 40.6 39.2 67.8 52.1 56.0 51.2 25.9 50.2 26.3 43.3 47.7 31.2 31.1 53.6 36.7 22.1 45.3 62.1 32.7 25.2 32.4 52.6 84.5 44.1 34.8 49.3 33.9 19.7 35.0 35.5 120.6 69.8 28.7 52.0 41.2 42.7 64.9 40.2 40.9 52.5 6.7 15.6 39.4 14.1 19.5 14.1 12.6 11.6 10.3 17.2 10.1 12.1 11.3 42.8 10.6 24.4 4.1 18.3 13.0 5.4 7.2 9.2 10.1 6.4 7.3 8.6 7.1 9.6 5.0 7.2 9.6 8.5 22.4 12.6 7.2 11.1 5.4 7.8 9.5 4.0 10.8 10.7 16.3 17.0 4.3 8.9 3.7 20.9 21.3 9.5 8.2 13.7 20.0 43.6 7.0 11.0 10.1 9.0 16.6 9.5 14.7 22.6 12.1 9.7 6.5 11.4 15.9 7.9 8.6 14.2 8.4 11.0 5.6 6.1 11.7 5.7 125.7 12.8 9.6 8.8 2.8 16.9 7.3 18.6 6.6 6.6 17.4 6.4 12.8 10.4 8.9 18.7 17.9 9.2 25.1 0.0 10.9 19.5 39.2 23.5 9.4 6.1 17.4 11.1 17.9 9.4 5.6 NIPSNAP1 ENSG00000184117 "Nipsnap homolog 1" Q9BPW8 22 29554808-29581327 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 291.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.7;Proximal tubular cells: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA059227 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA059227: AB_2683951" "unprognostic (7.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (2.15e-2)" "unprognostic (7.25e-2)" "unprognostic (6.91e-2)" "unprognostic (3.20e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.43e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "prognostic favorable (8.82e-6)" "unprognostic (2.81e-2)" "unprognostic (8.69e-2)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" 10.7 43.9 35.4 17.5 37.8 15.5 31.5 31.8 38.5 21.5 33.4 37.4 67.0 19.4 24.9 25.8 26.8 19.8 21.8 37.6 41.7 117.8 291.8 17.8 23.3 37.1 36.5 32.3 24.4 68.0 36.5 17.3 39.3 23.9 38.5 46.2 26.0 27.2 4.4 20.6 49.2 17.8 30.7 19.1 29.3 11.9 36.7 36.7 32.9 5.4 28.3 20.1 18.3 31.7 69.1 81.1 165.3 206.9 29.2 59.4 30.7 39.5 70.7 53.2 68.7 55.5 90.6 48.8 76.8 56.9 56.0 68.2 87.7 100.7 65.1 98.8 90.5 16.8 37.0 173.5 44.1 36.5 23.0 59.5 50.8 44.1 55.0 129.0 73.4 105.3 31.8 78.9 49.2 156.4 59.3 50.1 140.0 106.2 67.5 115.9 51.7 142.6 128.3 59.1 203.9 179.5 46.1 83.2 92.1 79.5 137.1 57.7 34.7 23.2 79.6 28.6 31.9 106.4 56.5 45.6 62.1 57.3 39.4 10.8 9.4 15.9 34.2 17.4 41.2 29.0 34.4 36.2 21.6 27.3 32.6 39.5 13.8 39.5 10.7 11.0 44.9 22.1 35.4 37.8 31.8 38.5 37.6 41.7 37.1 36.5 39.3 30.7 36.7 31.7 7.4 25.6 15.7 6.8 16.3 4.8 12.6 15.8 18.8 22.6 25.5 18.5 22.9 28.6 18.6 42.3 10.4 44.4 9.2 14.4 68.4 45.8 2.1 6.2 13.7 10.1 41.9 24.6 16.9 18.5 14.6 14.2 25.5 12.0 26.0 33.5 11.7 116.7 14.4 10.1 19.9 31.5 26.4 8.7 4.3 6.1 11.1 8.1 5.4 3.7 21.3 38.7 28.8 6.6 10.3 17.8 20.2 14.3 7.3 6.8 35.2 134.7 9.8 24.4 13.1 7.2 12.3 1.4 8.3 20.5 8.1 14.8 20.5 48.1 47.4 8.8 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 CABP7 MGC57793 ENSG00000100314 "Calcium binding protein 7" Q86V35 22 29720003-29731833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 38.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 28.6" "Group enriched" "Detected in some" 4 "glioma: 2.3;ovarian cancer: 1.0;pancreatic cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 10.3;SCLC-21H: 9.7;SH-SY5Y: 3.1;U-2 OS: 3.1" "Group enriched" "Detected in all" 4 "cerebellum: 74.4;hippocampal formation: 204.8;midbrain: 60.3;pons and medulla: 110.0" "Region enhanced" "Detected in all" "hippocampal formation: 51.0" HPA016439 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA016439: AB_2669357" "unprognostic (1.88e-1)" "unprognostic (4.75e-2)" "unprognostic (1.18e-1)" "unprognostic (5.37e-2)" "unprognostic (4.55e-1)" "unprognostic (2.29e-4)" "unprognostic (2.05e-3)" "unprognostic (7.96e-2)" "unprognostic (8.69e-3)" "unprognostic (3.32e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (7.44e-7)" "unprognostic (1.25e-4)" "unprognostic (3.60e-2)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" 0.1 5.6 3.1 0.0 3.0 0.2 0.1 19.8 35.0 0.1 0.6 0.8 0.4 0.1 0.0 0.1 0.1 0.0 0.2 38.2 4.2 0.2 0.3 0.1 0.1 27.7 14.8 0.1 3.1 0.0 0.4 0.0 30.0 0.4 0.0 1.0 0.2 0.0 0.1 0.2 1.5 0.0 22.2 0.4 0.3 0.6 3.9 0.0 0.3 0.0 0.0 0.1 0.1 16.5 0.1 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.5 10.3 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.0 0.0 9.7 3.1 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 3.1 0.1 0.2 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.1 3.1 3.0 19.8 35.0 38.2 4.2 27.7 14.8 30.0 22.2 3.9 16.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 28.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 1.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 1.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.0 ZMAT5 "SNRNP20, ZC3H19" ENSG00000100319 "Zinc finger matrin-type 5" Q9UDW3 22 29730956-29767011 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004858 Approved Supported Nucleoplasm NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA004858: AB_1080657" "unprognostic (2.14e-1)" "unprognostic (8.03e-3)" "unprognostic (1.23e-1)" "unprognostic (1.19e-2)" "unprognostic (1.02e-1)" "unprognostic (5.47e-3)" "unprognostic (6.04e-3)" "unprognostic (5.69e-2)" "unprognostic (5.75e-2)" "unprognostic (3.71e-2)" "unprognostic (2.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.03e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.62e-1)" "unprognostic (4.10e-2)" 14.3 26.0 25.8 10.6 26.4 14.2 14.5 26.5 34.9 17.1 25.9 19.6 12.2 18.0 19.8 21.1 20.5 10.0 25.5 25.3 26.0 21.3 26.8 13.7 15.0 27.5 26.5 16.2 20.4 23.0 10.6 8.4 25.5 19.2 7.2 7.8 18.2 16.6 37.1 18.1 14.4 13.8 26.0 19.9 20.1 10.6 27.2 17.8 19.1 24.5 12.2 19.0 15.8 26.8 17.9 22.1 19.3 37.5 23.7 26.2 8.7 19.4 23.9 28.5 34.7 19.4 11.0 12.2 18.9 20.8 22.0 16.5 16.5 19.9 18.6 39.2 36.3 46.9 10.8 36.3 43.8 21.6 14.8 22.7 30.2 36.5 22.2 24.2 30.4 19.0 12.3 25.9 23.8 26.7 31.0 22.5 7.2 34.7 25.9 37.1 34.2 32.6 22.8 10.9 14.8 27.4 18.1 22.4 27.9 10.9 33.7 30.0 19.4 38.8 19.4 26.4 29.2 24.0 20.5 20.4 29.9 25.6 27.9 48.1 84.6 95.3 46.1 94.6 47.3 61.6 47.7 48.6 73.9 60.3 41.8 49.1 69.5 60.8 94.7 57.6 61.0 65.3 25.8 26.4 26.5 34.9 25.3 26.0 27.5 26.5 25.5 26.0 27.2 26.8 17.0 16.0 20.8 6.2 14.6 9.6 21.0 32.0 10.2 12.7 16.2 22.6 1.4 17.2 20.4 14.7 18.8 21.5 11.3 16.4 33.2 35.3 0.9 13.8 14.3 15.2 14.4 8.6 3.7 27.3 18.1 15.9 13.3 10.4 33.7 13.0 15.0 17.1 45.1 5.0 5.1 19.4 24.4 21.4 17.9 3.0 15.8 22.1 12.4 3.7 27.7 26.0 34.0 6.0 6.5 31.7 18.1 21.8 14.9 12.4 27.8 40.0 19.3 21.4 32.9 15.1 40.0 11.0 22.8 14.0 11.8 14.1 18.0 18.2 14.4 18.9 UQCR10 "HSPC051, QCR9, UCCR7.2, UCRC" ENSG00000184076 "Ubiquinol-cytochrome c reductase, complex III subunit X" Q9UDW1 22 29767369-29770413 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 4406.3;Distal tubular cells: 2296.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (1.09e-1)" "unprognostic (2.96e-3)" "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (2.73e-2)" "unprognostic (1.25e-1)" "unprognostic (1.75e-3)" "unprognostic (3.05e-2)" "unprognostic (9.24e-3)" "unprognostic (2.94e-1)" "unprognostic (1.12e-2)" "prognostic favorable (5.45e-5)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.80e-3)" 87.8 167.6 175.5 59.0 182.2 72.2 70.8 186.9 221.3 58.7 180.2 124.6 111.7 54.0 72.1 111.0 70.4 52.4 433.7 181.4 186.4 169.9 170.0 75.4 68.4 177.2 175.8 61.9 73.4 142.8 98.8 53.7 177.0 94.6 87.6 90.4 85.4 64.0 509.1 73.7 98.2 52.9 179.6 89.8 121.7 101.7 182.0 81.0 86.3 463.5 65.8 79.5 71.0 178.1 173.3 177.3 167.7 131.3 154.0 100.8 93.1 93.8 116.2 164.1 170.8 230.4 96.8 129.6 99.6 149.7 120.5 168.2 200.6 219.9 101.8 162.6 423.2 162.2 200.9 512.2 110.1 210.7 170.0 169.8 132.0 171.6 115.1 137.4 124.1 137.3 112.6 169.8 163.8 434.9 159.4 246.5 96.6 413.1 232.4 171.3 134.6 235.1 289.7 324.3 184.6 92.9 109.3 231.7 156.2 105.7 164.5 198.9 98.2 168.4 204.8 104.8 141.3 127.2 140.2 176.0 152.2 161.4 108.7 982.0 782.2 1009.7 455.0 820.3 503.6 1000.7 620.1 587.4 842.3 830.2 670.6 571.5 552.9 554.9 762.4 864.6 890.3 1160.1 175.5 182.2 186.9 221.3 181.4 186.4 177.2 175.8 177.0 179.6 182.0 178.1 138.4 246.8 290.2 42.7 231.0 181.8 205.4 1090.3 149.1 167.6 354.1 421.9 4406.3 443.2 563.5 627.1 77.2 680.2 215.8 819.5 2296.9 438.5 356.7 361.2 190.9 200.9 380.1 380.7 26.0 553.2 549.2 291.0 423.5 345.2 150.1 279.1 180.2 1306.4 737.2 114.4 33.8 791.0 783.3 390.7 254.0 652.3 234.6 337.1 311.3 15.9 424.2 455.0 310.0 16.1 32.4 499.6 771.6 206.5 293.4 335.2 1114.8 1872.1 522.9 307.1 210.4 150.2 327.7 577.2 165.7 490.0 281.7 582.0 226.2 346.5 782.7 389.6 ASCC2 "ASC1p100, DKFZp586O0223, FLJ21588" ENSG00000100325 "Activating signal cointegrator 1 complex subunit 2" Q9H1I8 22 29788609-29838304 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001439, HPA052879" Approved Approved "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Focal adhesion sites, Cytosol" Nucleoplasm "HPA001439: AB_1078229, HPA052879: AB_2732577" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (8.58e-2)" "unprognostic (3.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.45e-3)" "unprognostic (3.01e-3)" "unprognostic (1.16e-1)" "unprognostic (1.35e-1)" "unprognostic (5.39e-2)" "unprognostic (1.56e-2)" "unprognostic (1.24e-1)" "unprognostic (3.97e-3)" "unprognostic (5.19e-2)" "unprognostic (7.53e-2)" "unprognostic (3.81e-1)" "unprognostic (2.05e-3)" 26.6 31.3 11.4 22.7 12.7 53.7 24.9 12.6 13.7 23.7 16.7 24.5 23.7 21.0 16.1 42.0 19.9 17.1 22.8 11.6 11.9 19.8 35.8 22.1 24.5 13.5 12.9 19.9 23.5 21.8 26.7 21.8 13.2 27.1 24.6 8.4 29.8 18.0 43.5 30.1 23.1 19.2 12.9 29.4 37.0 24.5 12.5 29.6 28.3 32.3 34.0 26.8 27.5 13.3 46.9 26.8 28.4 38.7 41.6 36.7 40.7 47.6 36.3 48.4 48.1 31.5 24.7 46.5 33.4 46.2 30.7 55.5 36.8 54.0 40.5 59.8 64.3 39.9 33.0 38.0 52.1 72.3 115.6 39.6 48.2 55.0 50.0 28.4 42.9 30.7 41.8 43.7 44.3 57.8 44.5 37.9 20.7 65.6 36.0 53.0 34.9 48.6 29.6 76.1 43.8 38.5 44.3 48.2 35.4 28.8 34.3 37.4 42.8 67.1 11.3 41.2 47.9 51.9 42.8 54.4 39.2 39.9 49.5 44.7 29.8 53.6 32.1 49.2 28.4 18.8 23.6 26.9 37.7 15.0 24.1 24.6 9.2 33.7 43.9 21.7 30.3 20.0 11.4 12.7 12.6 13.7 11.6 11.9 13.5 12.9 13.2 12.9 12.5 13.3 27.7 19.2 14.7 18.6 35.8 30.0 25.2 38.1 13.1 9.4 23.3 12.3 19.1 31.5 33.3 40.5 4.2 46.3 40.5 38.8 11.7 25.4 110.2 14.0 28.1 20.7 15.5 116.0 13.5 24.9 63.3 22.9 69.8 20.0 34.9 24.3 22.9 25.7 30.6 5.0 13.8 23.2 44.7 29.2 37.3 155.2 31.1 29.1 28.4 11.2 27.9 12.2 56.7 15.6 16.3 27.7 34.0 24.8 32.4 16.2 46.8 18.2 24.4 13.6 19.7 19.6 19.7 48.4 22.5 35.0 39.2 44.3 34.9 27.8 23.9 34.2 MTMR3 "FYVE-DSP1, KIAA0371, ZFYVE10" ENSG00000100330 "Myotubularin related protein 3" Q13615 22 29883169-30030868 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.6" "Cell type enhanced" "Detected in many" "Astrocytes: 111.3;Inhibitory neurons: 78.3;Microglial cells: 90.9;Oligodendrocyte precursor cells: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034515, HPA034516, HPA061399" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Cytosol "HPA034515: AB_10669726, HPA034516: AB_10669727, HPA061399: " "unprognostic (4.39e-3)" "unprognostic (7.84e-2)" "unprognostic (2.46e-2)" "unprognostic (1.76e-2)" "unprognostic (5.61e-2)" "unprognostic (4.51e-3)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (3.42e-1)" "unprognostic (4.39e-1)" "unprognostic (8.33e-4)" "unprognostic (1.28e-1)" "unprognostic (5.35e-4)" "unprognostic (7.96e-2)" "unprognostic (7.64e-2)" "unprognostic (2.49e-1)" "unprognostic (8.38e-2)" 17.8 18.4 18.5 13.0 19.4 81.6 17.0 21.2 18.6 18.9 17.0 15.5 11.1 16.0 12.8 22.4 16.4 12.5 13.9 20.8 19.3 11.7 10.8 20.7 11.5 19.2 19.8 20.4 16.5 18.3 17.0 15.0 17.3 16.0 12.7 21.2 17.2 11.3 36.7 25.5 14.5 14.8 18.6 21.7 15.7 26.2 21.6 16.2 17.2 30.0 13.9 15.1 19.4 16.6 13.4 11.7 17.0 18.3 16.7 12.1 12.8 12.2 17.4 15.7 18.2 10.0 7.9 10.2 7.6 22.1 12.4 16.0 18.5 14.3 16.6 21.0 15.4 18.6 10.6 10.1 15.3 15.9 45.0 12.8 22.9 14.9 26.9 14.7 15.3 10.7 11.6 17.5 10.3 16.2 10.7 11.1 6.5 13.7 7.5 12.5 23.3 10.4 14.1 24.3 19.2 13.1 22.1 19.7 11.7 14.1 11.2 15.3 16.8 25.3 16.7 5.5 8.3 14.7 11.1 9.3 11.0 7.5 11.8 8.3 7.4 11.2 3.2 4.9 4.0 2.3 2.5 3.4 4.1 2.4 3.1 2.7 17.8 4.1 5.4 1.5 2.9 4.3 18.5 19.4 21.2 18.6 20.8 19.3 19.2 19.8 17.3 18.6 21.6 16.6 15.9 3.2 14.8 111.3 13.3 16.7 9.8 11.5 14.8 0.0 13.7 11.0 4.2 10.0 17.7 12.9 0.0 13.6 10.4 21.5 1.9 9.5 14.0 16.8 14.9 10.6 12.5 21.0 61.2 8.8 7.0 12.6 31.6 24.5 7.6 14.7 13.9 10.1 10.9 0.0 78.3 9.2 46.8 20.6 11.7 16.7 13.7 20.8 14.2 90.9 22.3 0.0 12.3 96.5 73.2 12.3 11.1 11.3 13.0 14.6 12.2 7.3 16.4 0.0 6.6 15.3 11.0 26.8 28.0 18.1 13.8 13.7 13.0 8.9 11.5 21.2 HORMAD2 "CT46.2, MGC26710" ENSG00000176635 "HORMA domain containing 2" Q8N7B1 22 30080464-30177075 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 22.8" "Group enriched" "Detected in some" 7 "Early spermatids: 52.8;Spermatocytes: 133.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003074, HPA043880" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Centrosome, Cytosol" "HPA003074: AB_1850916, HPA043880: " "unprognostic (1.43e-1)" "unprognostic (6.77e-3)" "unprognostic (2.33e-1)" "unprognostic (1.36e-2)" "unprognostic (8.19e-3)" "unprognostic (1.96e-1)" "unprognostic (2.50e-2)" "unprognostic (2.12e-1)" 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.9 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 22.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.4 0.3 0.3 0.3 0.3 0.3 0.3 0.1 0.0 0.0 3.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.8 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.7 3.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 9.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.2 0.0 133.0 12.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 LIF "CDF, DIA, HILDA" ENSG00000128342 "LIF interleukin 6 family cytokine" P15018 22 30240453-30246759 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 47.7;urinary bladder: 91.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 95.5;Club cells: 56.3;Endometrial ciliated cells: 71.7;Fibroblasts: 51.9;Glandular and luminal cells: 192.9;granulocytes: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 88.3;hTEC/SVTERT24-B: 113.0;hTERT-RPE1: 104.4;U-138 MG: 123.9;U-251 MG: 94.5;U-87 MG: 97.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018844, CAB025985" Uncertain Supported Cytosol "Secreted in other tissues" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" Cytosol "CAB025985: , HPA018844: AB_1852814" "unprognostic (1.28e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (8.79e-2)" "unprognostic (4.61e-2)" "unprognostic (7.36e-3)" "unprognostic (4.18e-3)" "unprognostic (1.17e-2)" "unprognostic (1.41e-2)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (9.65e-2)" "prognostic unfavorable (6.78e-8)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (8.99e-2)" "unprognostic (4.71e-3)" 37.9 4.3 0.6 22.4 0.7 1.6 4.7 0.6 1.7 6.8 6.6 7.5 6.7 11.7 0.6 3.1 9.8 47.7 18.4 0.9 0.8 14.2 5.0 29.9 4.3 1.2 1.3 2.3 13.4 0.4 10.4 2.7 0.9 12.0 8.0 3.0 4.9 2.1 0.8 10.7 9.3 8.3 1.1 1.5 7.8 0.6 2.6 1.3 5.4 1.0 1.7 91.0 2.4 1.1 29.0 47.9 1.3 10.6 0.0 3.9 17.1 4.1 17.2 5.1 12.1 7.7 47.3 0.0 10.1 0.2 88.3 7.3 1.1 13.1 6.9 6.8 2.1 3.7 19.7 10.9 4.5 0.1 36.7 4.3 2.5 113.0 3.3 104.4 0.0 0.2 0.8 0.1 22.6 21.5 0.6 0.1 1.8 27.0 29.5 0.9 15.9 0.0 40.7 11.0 0.2 0.6 4.9 0.4 8.8 5.0 1.0 0.5 0.3 123.9 45.3 47.3 94.5 0.0 0.2 0.1 97.4 0.1 58.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.7 0.6 1.7 0.9 0.8 1.2 1.3 0.9 1.1 2.6 1.1 0.6 22.4 44.2 0.3 0.0 3.4 14.0 95.5 0.0 0.1 40.0 10.9 0.2 10.0 56.3 5.5 0.0 0.2 2.9 3.9 0.0 39.6 0.3 71.7 16.2 3.6 0.0 0.0 0.0 3.4 0.7 51.9 0.5 192.9 67.0 0.2 0.0 0.0 1.1 0.0 0.0 3.5 10.2 0.6 3.2 0.0 0.0 3.9 0.0 0.0 0.0 1.7 0.0 0.0 0.0 40.3 3.8 0.0 0.4 15.7 5.3 1.0 15.6 0.2 0.0 17.7 30.2 0.1 0.2 1.5 2.8 0.3 5.5 0.1 7.1 20.3 OSM MGC20461 ENSG00000099985 "Oncostatin M" P13725 22 30262829-30266851 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth regulation" "Cytokine, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 118.2" "Group enriched" "Detected in some" 4 "Hofbauer cells: 74.4;Macrophages: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "basophil: 65.2;neutrophil: 34.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "HDLM-2: 15.7;HL-60: 3.8;HMC-1: 11.1;Karpas-707: 3.5;NB-4: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 39700 "Cluster 38: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "unprognostic (5.15e-2)" "unprognostic (8.80e-3)" "unprognostic (1.01e-1)" "unprognostic (6.02e-2)" "unprognostic (7.37e-2)" "unprognostic (2.61e-2)" "unprognostic (6.78e-2)" "unprognostic (3.77e-2)" "unprognostic (2.81e-2)" "unprognostic (4.60e-2)" "unprognostic (1.58e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.03e-5)" "unprognostic (4.00e-2)" "unprognostic (7.72e-2)" "unprognostic (1.52e-1)" "unprognostic (1.82e-1)" 7.2 3.6 0.8 14.3 1.0 118.2 0.8 0.8 4.2 1.2 2.0 1.0 0.5 1.1 0.1 0.8 2.3 6.2 1.4 0.6 1.5 2.0 1.9 7.8 1.6 1.8 0.9 0.5 1.2 0.9 1.5 5.5 1.7 1.0 0.5 0.1 1.1 0.2 0.2 0.2 0.7 3.1 1.6 5.0 0.9 0.4 4.7 2.6 0.8 2.9 0.8 12.7 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.7 0.0 0.3 0.0 0.0 0.0 3.8 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 3.5 0.0 0.0 0.5 6.6 0.0 0.0 0.0 0.6 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.3 0.0 65.2 0.5 2.0 2.0 0.3 6.5 0.0 4.8 2.6 0.8 0.2 0.9 2.4 34.9 4.3 0.1 0.2 1.4 1.6 0.8 1.0 0.8 4.2 0.6 1.5 1.8 0.9 1.7 1.6 4.7 2.9 0.9 9.6 10.6 0.0 3.2 0.8 0.2 0.0 0.0 0.0 0.7 1.8 0.6 0.0 3.7 0.0 0.0 0.8 13.2 0.0 0.0 0.1 0.1 0.6 0.2 1.9 0.0 1.3 0.1 0.0 0.9 1.4 0.0 1.1 15.2 0.0 0.4 0.0 74.4 0.0 0.1 0.1 0.0 6.1 12.4 0.0 0.0 51.6 0.0 0.0 1.8 0.1 1.0 0.0 0.1 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.7 0.2 0.0 0.7 0.4 0.0 0.0 0.3 0.3 0.8 14.2 0.1 0.0 0.0 CASTOR1 GATSL3 ENSG00000239282 "Cytosolic arginine sensor for mTORC1 subunit 1" Q8WTX7 22 30285117-30289622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 48.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.8;Extravillous trophoblasts: 55.4;monocytes: 45.5;Syncytiotrophoblasts: 36.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073183 Approved NA NA "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "HPA073183: " "unprognostic (1.48e-2)" "unprognostic (1.48e-2)" "unprognostic (1.92e-3)" "unprognostic (7.40e-3)" "unprognostic (2.75e-2)" "unprognostic (2.45e-2)" "unprognostic (8.60e-2)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (3.95e-1)" "unprognostic (3.95e-2)" "unprognostic (3.32e-2)" "unprognostic (3.37e-5)" "unprognostic (9.28e-2)" "unprognostic (8.70e-2)" "unprognostic (3.17e-2)" "unprognostic (4.26e-2)" 12.7 6.4 11.5 3.3 11.3 1.5 13.3 9.9 15.8 24.7 10.1 7.3 0.6 9.1 2.5 48.0 11.1 4.3 9.3 10.6 11.0 12.3 7.5 10.9 7.2 11.0 11.8 13.8 5.5 14.5 8.6 11.0 10.4 13.5 0.6 1.2 12.0 11.9 2.7 12.3 5.9 3.3 9.9 9.3 7.8 17.2 11.5 4.8 13.1 3.1 3.4 10.3 35.2 9.9 1.5 5.9 1.8 6.2 6.6 7.3 12.6 0.5 1.5 0.9 1.0 2.1 1.4 0.5 1.9 3.5 9.4 2.9 1.8 2.4 0.1 0.9 1.4 0.4 1.1 1.7 13.5 0.5 4.5 12.9 5.4 3.0 0.5 9.4 6.1 10.8 1.3 5.2 3.5 7.6 3.4 4.0 1.0 6.2 2.8 5.0 3.2 5.0 3.5 2.0 0.4 4.2 1.8 3.8 1.4 5.5 5.8 0.7 4.8 3.6 3.8 2.3 0.4 0.4 0.4 0.3 1.7 2.2 1.3 12.2 7.6 19.5 9.8 5.1 5.9 15.6 12.9 10.4 7.6 16.3 21.4 16.0 3.0 29.2 2.6 8.2 14.8 7.5 11.5 11.3 9.9 15.8 10.6 11.0 11.0 11.8 10.4 9.9 11.5 9.9 13.6 0.0 2.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 7.0 5.7 0.0 0.0 1.8 7.3 0.0 71.8 2.6 0.0 9.8 6.0 0.0 1.5 1.3 2.4 0.0 0.0 0.0 2.4 55.4 3.1 0.0 4.0 2.5 2.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 45.5 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 11.6 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 36.4 1.5 2.6 0.0 0.0 AC004997.1 ENSG00000248751 "Novel protein" 22 30285238-30299482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 1.3;Karpas-707: 1.0;LHCN-M2: 1.0" HPA073183 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "HPA073183: " "unprognostic (2.09e-1)" "unprognostic (1.68e-2)" "unprognostic (1.01e-2)" "unprognostic (2.64e-2)" "unprognostic (3.83e-2)" "unprognostic (7.25e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-3)" "unprognostic (1.18e-2)" "unprognostic (2.46e-1)" "unprognostic (9.84e-2)" "unprognostic (1.92e-1)" "unprognostic (1.83e-5)" "unprognostic (7.90e-2)" "unprognostic (7.28e-2)" "unprognostic (4.96e-3)" "unprognostic (1.02e-2)" 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.0 0.3 0.1 0.2 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.3 0.0 0.2 0.0 0.1 0.3 0.0 0.3 0.4 0.3 0.2 0.0 0.1 0.0 0.2 0.0 0.7 0.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 1.0 0.0 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.3 0.0 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.2 0.4 0.5 0.4 0.1 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.6 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D10A "AC004997.C22.2, EPI64, TBC1D10" ENSG00000099992 "TBC1 domain family member 10A" Q9BXI6 22 30291990-30326947 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007725, HPA008142, HPA076041" Approved Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA007725: AB_2667907, HPA008142: AB_1080209, HPA076041: AB_2686772" "unprognostic (3.37e-2)" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (1.10e-2)" "unprognostic (2.11e-3)" "unprognostic (1.20e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (4.28e-1)" "unprognostic (6.40e-2)" "unprognostic (1.08e-1)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.05e-2)" "unprognostic (7.52e-2)" 22.6 17.0 6.9 10.2 8.2 8.2 23.7 5.8 10.2 29.6 9.3 18.3 8.6 14.7 4.6 44.1 14.9 12.7 11.2 7.5 9.3 21.3 17.9 23.7 17.2 7.4 8.1 21.1 10.8 24.5 19.5 17.5 7.0 21.3 5.5 10.8 23.2 12.9 5.6 45.3 17.3 6.8 6.2 24.2 17.3 21.6 9.7 18.4 19.0 6.9 10.4 19.9 39.9 6.4 18.9 7.1 2.9 9.0 8.4 10.8 23.9 10.7 14.9 11.8 18.7 8.4 7.2 9.5 10.2 17.8 16.2 18.3 4.3 9.9 6.2 7.2 12.4 2.6 6.4 6.0 21.9 3.7 12.9 14.0 15.5 23.4 4.0 12.3 5.5 20.5 5.1 8.8 8.9 22.1 26.9 7.9 1.9 33.9 9.5 12.3 12.4 8.8 11.6 17.9 4.9 3.8 11.0 15.7 24.5 7.8 13.8 2.3 10.8 22.9 10.4 13.1 5.8 8.8 4.2 8.3 15.6 5.6 13.1 37.5 14.9 37.9 26.6 30.1 29.3 13.4 30.9 27.2 21.7 20.7 40.7 34.0 10.6 24.3 45.5 37.5 28.8 28.4 6.9 8.2 5.8 10.2 7.5 9.3 7.4 8.1 7.0 6.2 9.7 6.4 27.8 6.4 3.4 24.8 18.2 49.2 40.2 40.3 32.5 7.8 18.4 12.4 2.7 14.3 23.6 5.5 18.8 57.6 19.5 26.8 23.5 20.1 10.7 8.8 5.4 14.4 10.7 3.0 3.0 10.2 80.6 18.3 19.4 16.4 9.5 20.1 11.0 8.6 27.5 1.7 3.5 14.2 18.3 12.9 46.0 6.9 21.8 15.9 26.6 10.3 78.1 28.1 28.8 2.5 1.0 18.7 18.7 9.1 12.3 24.3 14.9 20.5 6.6 39.3 39.5 7.4 17.1 33.2 13.5 27.6 37.1 116.3 28.0 20.2 11.0 28.3 SF3A1 "Prp21, PRPF21, SAP114, SF3a120" ENSG00000099995 "Splicing factor 3a subunit 1" Q15459 22 30331988-30356919 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000690, HPA030083" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA 87000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Nuclear speckles" "HPA000690: AB_1079933, HPA030083: AB_10602183" "unprognostic (8.61e-2)" "unprognostic (1.60e-1)" "unprognostic (3.21e-2)" "unprognostic (7.54e-2)" "unprognostic (5.06e-3)" "unprognostic (1.79e-1)" "unprognostic (5.54e-3)" "unprognostic (3.30e-1)" "unprognostic (3.83e-1)" "unprognostic (2.59e-1)" "unprognostic (2.58e-1)" "unprognostic (3.26e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (6.97e-2)" "unprognostic (1.13e-1)" 36.2 29.7 14.1 45.4 19.0 58.0 35.0 19.2 20.5 33.4 12.6 31.2 29.8 36.3 20.5 34.0 31.8 21.3 28.0 15.3 12.7 25.5 27.5 31.0 44.1 16.6 14.8 46.4 32.9 42.8 24.3 29.0 14.1 29.4 27.0 36.4 33.3 28.1 51.1 40.5 32.8 29.9 13.3 42.0 31.8 49.2 15.9 42.6 31.6 25.8 41.4 33.2 32.8 20.7 86.2 58.9 79.4 77.6 46.4 41.3 94.8 66.5 42.7 71.4 52.8 78.8 55.9 106.4 44.6 47.7 55.9 80.4 101.6 70.8 77.7 97.4 88.4 99.3 69.1 65.3 41.8 202.1 106.3 41.7 49.6 89.5 72.4 40.1 52.1 56.6 112.5 108.0 52.8 49.1 99.4 46.2 132.0 65.7 48.4 139.5 99.4 86.8 40.9 93.6 82.2 74.9 84.4 50.8 78.4 52.5 62.3 65.4 72.9 90.2 80.0 65.1 124.4 83.2 108.2 106.9 69.4 73.8 95.0 6.7 8.9 14.1 10.9 9.8 11.2 10.4 11.0 11.8 9.2 11.0 12.0 11.2 14.1 11.0 13.0 5.6 14.5 8.0 14.1 19.0 19.2 20.5 15.3 12.7 16.6 14.8 14.1 13.3 15.9 20.7 32.4 57.7 66.5 12.1 60.8 26.1 25.4 19.0 37.0 17.6 25.7 24.4 27.6 34.3 30.5 31.3 16.7 32.5 49.2 30.8 17.6 25.7 106.1 30.5 23.1 32.6 25.1 36.1 7.5 29.4 39.7 29.1 35.2 29.1 52.6 76.3 28.2 28.4 40.6 26.9 9.4 30.7 16.2 37.2 28.3 116.8 35.1 39.8 17.8 5.6 58.5 27.1 46.4 6.0 7.1 28.8 31.3 37.6 45.5 26.4 31.8 17.0 39.4 20.3 46.0 29.0 27.3 64.3 41.6 37.8 27.3 34.6 55.8 26.7 33.9 25.8 CCDC157 ENSG00000187860 "Coiled-coil domain containing 157" Q569K6 22 30356635-30378658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.6" "Cell type enhanced" "Detected in many" "Early spermatids: 118.0;Late spermatids: 142.4;Respiratory ciliated cells: 44.9;Spermatocytes: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA042943 Uncertain NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "HPA042943: AB_10794767" "unprognostic (3.69e-3)" "unprognostic (1.72e-4)" "unprognostic (4.35e-2)" "unprognostic (1.24e-2)" "unprognostic (3.61e-1)" "unprognostic (7.74e-3)" "unprognostic (8.72e-4)" "unprognostic (1.35e-2)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (6.89e-4)" "unprognostic (2.33e-2)" "unprognostic (2.60e-2)" "unprognostic (4.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.42e-1)" "unprognostic (3.45e-2)" 0.7 1.4 3.9 0.9 3.5 1.8 1.2 2.9 3.8 1.5 7.3 0.9 0.9 1.0 1.8 1.1 7.4 1.2 0.7 3.8 4.1 3.0 0.9 2.2 1.1 4.3 5.9 1.2 1.9 2.2 5.0 0.5 3.3 1.7 0.4 1.9 1.5 0.9 0.6 1.0 1.2 0.4 3.6 1.6 1.1 27.6 5.0 0.8 3.6 0.5 0.7 0.9 1.0 2.7 1.8 2.0 1.8 3.4 1.0 0.6 2.2 0.9 1.1 1.7 1.7 2.6 1.3 1.6 1.1 0.9 2.6 1.9 1.0 1.2 0.9 1.1 4.3 0.9 2.0 1.4 1.1 1.7 1.4 0.6 0.8 3.1 0.5 1.1 1.0 2.3 1.5 1.4 1.4 1.6 2.2 1.8 2.4 1.2 1.0 1.9 1.0 1.4 4.2 1.8 6.1 4.0 2.8 1.1 1.2 1.3 3.3 0.8 1.8 1.8 2.2 1.1 0.8 1.2 0.7 1.2 2.7 1.0 1.4 0.8 0.6 0.8 0.7 0.4 0.8 0.4 0.7 0.8 0.3 0.5 0.4 0.6 2.5 0.7 0.6 0.9 0.7 0.5 3.9 3.5 2.9 3.8 3.8 4.1 4.3 5.9 3.3 3.6 5.0 2.7 2.6 3.2 3.3 2.0 2.6 1.3 2.4 4.2 0.6 6.2 6.6 5.2 0.9 4.3 7.3 9.2 12.5 2.5 7.0 3.0 0.0 5.5 118.0 31.3 3.3 2.8 1.2 0.4 4.2 2.3 2.3 2.6 2.0 5.0 2.5 3.8 5.7 0.9 2.0 6.7 3.1 1.5 8.2 3.8 3.9 142.4 3.7 3.4 0.0 1.0 2.2 4.4 4.1 1.0 0.6 3.0 3.2 2.6 6.6 1.4 1.7 6.9 44.9 28.3 0.0 6.7 3.8 59.3 16.5 1.5 1.7 3.4 4.8 4.5 1.8 1.9 RNF215 ENSG00000099999 "Ring finger protein 215" Q9Y6U7 22 30368811-30421771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.9;Cone photoreceptor cells: 12.5;Rod photoreceptor cells: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029427, HPA056498" Approved Approved Nucleoli,Microtubules NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 5: Muller glia cells - Visual perception" Microtubules Nucleoli "HPA029427: AB_2732447, HPA056498: AB_2683154" "unprognostic (1.24e-2)" "unprognostic (3.20e-1)" "unprognostic (3.67e-4)" "unprognostic (8.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (2.47e-2)" "unprognostic (1.97e-1)" "unprognostic (5.32e-2)" "unprognostic (1.03e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (6.37e-10)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (3.17e-1)" "unprognostic (1.78e-2)" 8.4 8.7 19.2 5.6 19.0 7.0 9.3 18.7 22.5 17.6 17.9 11.8 7.8 15.2 9.2 6.7 13.3 6.8 9.5 19.2 20.4 12.1 11.1 8.7 4.7 20.2 18.7 13.7 13.2 10.7 10.0 6.9 18.3 13.1 3.9 8.5 6.5 8.3 8.0 6.1 7.7 7.9 16.9 11.6 8.9 10.5 20.0 2.8 12.2 2.9 3.9 12.3 10.8 17.4 6.8 14.0 14.4 23.4 13.8 14.3 14.2 11.4 10.1 11.3 6.8 3.8 7.4 2.7 20.1 9.3 21.1 8.4 8.9 13.1 9.0 15.8 10.8 4.5 17.8 5.1 18.9 3.6 18.5 19.4 15.8 19.3 10.3 36.7 13.3 7.0 4.0 12.6 13.6 11.0 2.6 8.5 4.5 9.7 15.4 12.2 8.4 10.8 14.9 10.3 6.3 16.2 11.6 8.3 8.9 13.1 7.6 3.9 18.6 30.2 13.3 8.8 6.7 13.3 3.4 3.7 17.7 2.6 11.9 0.4 0.9 1.5 0.9 0.7 1.0 1.0 1.0 0.8 0.5 1.9 1.8 1.7 0.5 2.5 0.8 1.4 0.5 0.4 19.2 19.0 18.7 22.5 19.2 20.4 20.2 18.7 18.3 16.9 20.0 17.4 7.1 3.2 3.9 8.8 1.4 0.3 1.2 1.6 2.8 12.9 3.2 3.9 2.2 1.5 2.7 0.0 12.5 1.9 3.7 1.0 0.0 1.5 0.8 3.7 6.4 3.5 0.0 0.4 5.0 1.4 1.5 5.4 6.1 6.6 0.0 8.2 4.6 2.3 1.8 8.4 4.6 0.5 2.0 1.2 0.5 0.4 0.9 1.9 1.8 1.0 2.3 11.7 1.0 2.5 1.1 1.9 0.2 1.2 1.8 1.3 0.7 1.0 0.6 13.7 6.6 4.8 4.8 2.1 0.9 0.6 0.1 1.6 2.0 5.3 0.7 1.2 SEC14L2 "C22orf6, KIAA1186, KIAA1658, SPF, TAP, TAP1" ENSG00000100003 "SEC14 like lipid binding 2" O76054 22 30396941-30425303 "Predicted intracellular proteins" "Transcription, Transcription regulation, Transport" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 86.0;liver: 243.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 146.3;Muller glia cells: 112.6;Pancreatic endocrine cells: 115.2;Proximal enterocytes: 52.8;Rod photoreceptor cells: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.7;naive CD8 T-cell: 2.7" "Lineage enriched" "Detected in single" 7 "T-cells: 3.7" "Cell line enhanced" "Detected in many" "HBEC3-KT: 93.9;hTCEpi: 47.3;hTERT-RPE1: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064466 Approved Supported Nucleoplasm,Cytosol NA NA 580000 "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm Cytosol "HPA064466: AB_2685270" "prognostic favorable (3.05e-4)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (5.59e-3)" "unprognostic (6.51e-2)" "prognostic unfavorable (7.63e-6)" "unprognostic (1.25e-3)" "unprognostic (3.76e-3)" "unprognostic (2.23e-1)" "unprognostic (2.40e-1)" "unprognostic (2.76e-2)" "unprognostic (5.63e-3)" "unprognostic (1.17e-3)" "unprognostic (1.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.34e-3)" "unprognostic (2.01e-1)" 2.8 1.4 33.1 2.6 43.3 4.1 44.4 35.8 37.1 6.0 35.4 3.4 21.6 3.4 86.0 20.6 3.1 7.4 2.4 34.3 39.7 8.0 243.8 2.7 3.1 45.4 39.5 2.6 2.6 11.0 11.1 1.5 33.2 52.3 1.3 64.2 9.3 13.7 0.7 7.0 24.3 3.4 30.4 1.1 5.9 1.3 41.4 4.2 9.0 0.5 4.5 3.2 7.7 32.2 24.8 5.5 5.0 6.4 6.5 16.8 0.4 18.0 15.5 12.0 13.1 1.6 15.9 0.5 5.6 22.7 20.5 20.0 3.0 93.9 13.8 2.2 4.1 0.4 5.4 8.0 9.2 0.0 7.1 11.5 47.3 11.5 20.8 55.5 29.7 4.2 0.1 0.5 22.2 4.0 3.0 0.5 0.1 13.9 7.6 1.2 8.0 0.6 20.7 7.8 2.8 3.1 13.3 3.2 11.2 0.6 14.7 0.5 41.2 15.8 10.4 6.8 12.7 0.3 0.2 0.8 32.4 0.1 12.6 0.0 0.1 0.2 0.5 0.1 0.2 0.4 1.4 0.3 0.0 0.3 3.7 2.7 0.3 0.0 0.0 0.5 0.7 0.8 33.1 43.3 35.8 37.1 34.3 39.7 45.4 39.5 33.2 30.4 41.4 32.2 1.1 3.2 5.8 33.6 1.1 4.1 18.0 25.2 6.8 9.2 36.5 21.7 1.2 12.8 10.3 0.0 16.7 4.2 3.2 0.6 5.9 22.9 8.3 2.9 2.3 2.4 1.2 17.2 9.8 18.7 0.3 5.1 5.6 5.8 5.7 0.7 7.1 146.3 0.5 13.5 6.7 2.0 4.1 4.4 0.4 10.7 1.2 2.6 7.2 1.9 0.2 112.6 0.0 21.6 13.2 115.2 0.0 0.7 2.5 15.3 52.8 8.7 3.9 56.0 0.0 2.8 4.0 0.6 1.2 5.6 2.0 3.0 7.4 0.1 2.1 7.8 AC004832.3 ENSG00000249590 "Novel SEC14-like 2 (S. cerevisiae) (SEC14L2) and mitochondrial protein 18 kDa (MTP18) protein" 22 30409255-30428990 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "retina: 6.8" "Cell type enhanced" "Detected in single" "Distal tubular cells: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBF TERT88: 8.4;HUVEC TERT2: 2.2" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 39: Non-specific - Basic cellular processes" 0.1 0.2 0.3 0.8 0.5 0.1 0.1 0.4 1.7 0.1 2.0 0.4 0.3 0.1 1.0 0.2 0.1 0.2 0.3 0.4 0.4 1.5 2.0 0.3 0.0 0.7 0.5 0.1 0.2 0.0 0.0 0.0 0.6 0.5 1.4 6.8 0.1 0.0 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.4 0.8 0.0 0.2 0.2 0.8 0.0 0.1 0.8 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.3 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 1.2 1.2 2.2 0.0 0.0 0.2 1.2 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.3 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.3 0.5 0.4 1.7 0.4 0.4 0.7 0.5 0.6 0.6 0.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MTFP1 "HSPC242, MTP18" ENSG00000242114 "Mitochondrial fission process 1" Q9UDX5 22 30425623-30429054 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 69.7;Exocrine glandular cells: 52.2;Plasma cells: 43.5;Undifferentiated cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077396 Approved Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Mitochondria "HPA077396: AB_2686837" "unprognostic (2.19e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-1)" "unprognostic (6.20e-2)" "unprognostic (4.86e-2)" "unprognostic (1.72e-3)" "unprognostic (1.52e-3)" "unprognostic (8.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (6.37e-3)" "unprognostic (1.54e-1)" "unprognostic (1.49e-1)" "unprognostic (6.40e-2)" "unprognostic (3.06e-2)" "unprognostic (3.84e-1)" "unprognostic (1.66e-2)" 12.9 15.6 8.7 10.1 9.1 14.2 11.6 11.1 9.9 8.3 16.8 17.1 16.8 3.8 15.1 19.8 3.4 8.1 26.2 9.0 10.2 38.9 31.9 11.9 16.5 9.9 9.7 5.0 19.0 21.8 8.1 11.4 9.3 13.5 12.9 23.4 10.1 4.9 26.2 7.6 13.4 4.7 9.1 20.9 19.7 4.0 10.8 7.8 8.5 19.3 14.8 13.7 7.6 8.6 91.9 69.5 23.8 37.1 5.1 4.1 27.2 8.6 8.2 51.3 78.5 33.6 52.4 99.5 25.3 6.0 41.3 46.5 74.0 77.6 34.7 56.2 96.5 26.7 38.6 64.9 14.8 66.7 52.7 7.6 25.7 31.4 47.4 15.7 43.5 45.1 51.2 35.5 16.3 109.5 63.3 71.8 41.5 82.9 73.2 85.6 23.1 87.3 61.0 24.8 40.6 44.5 19.9 90.6 35.6 16.9 28.8 31.4 18.4 55.9 72.4 27.6 26.3 17.8 15.5 86.1 22.4 75.9 23.7 0.2 14.3 0.1 49.2 17.1 65.5 34.0 39.6 42.3 20.3 23.7 41.7 48.2 1.8 14.0 11.6 10.5 36.0 25.6 8.7 9.1 11.1 9.9 9.0 10.2 9.9 9.7 9.3 9.1 10.8 8.6 5.3 6.4 3.0 3.9 21.7 5.6 1.8 12.0 6.2 0.0 10.1 3.7 4.4 7.2 6.7 3.7 0.0 13.4 14.8 33.2 15.6 69.7 0.1 1.9 1.4 5.8 8.4 9.2 0.8 52.2 30.4 2.5 20.9 2.6 9.5 0.4 5.0 11.1 17.6 0.0 2.7 28.1 2.0 10.3 9.6 0.2 0.6 6.4 3.6 1.0 36.6 0.0 10.3 0.5 0.3 40.3 13.8 0.4 43.5 3.5 28.3 11.8 1.9 0.0 0.0 1.5 5.1 0.6 2.1 16.5 5.5 16.8 29.6 0.7 45.3 2.2 SEC14L3 TAP2 ENSG00000100012 "SEC14 like lipid binding 3" Q9UDX4 22 30447959-30472017 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.8;liver: 2.9;retina: 9.0" "Group enriched" "Detected in some" 8 "Muller glia cells: 27.6;Respiratory ciliated cells: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA059450 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" "HPA059450: AB_2684024" "unprognostic (2.42e-1)" "unprognostic (2.56e-1)" "unprognostic (1.42e-1)" "unprognostic (5.35e-2)" "unprognostic (2.00e-4)" "unprognostic (3.62e-3)" "unprognostic (6.68e-2)" "unprognostic (3.19e-1)" "unprognostic (2.41e-10)" "unprognostic (1.27e-1)" "unprognostic (2.09e-1)" "unprognostic (4.10e-1)" 0.0 0.1 0.2 0.1 0.1 3.8 0.0 0.3 0.3 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.0 0.0 2.9 1.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.3 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.4 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 2.7 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEC14L4 "dJ130H16.5, TAP3" ENSG00000133488 "SEC14 like lipid binding 4" Q9UDX3 22 30488902-30505711 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.2;liver: 19.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 22.4;Alveolar cells type 2: 6.9;Cholangiocytes: 11.5;Erythroid cells: 26.5;Hepatocytes: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 4.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.0" "Cell line enriched" "Detected in some" 4 "BEWO: 37.7" "Region enhanced" "Detected in single" "thalamus: 1.2" HPA069748 Approved Centrosome NA NA 82000 "Cluster 6: Non-specific - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Centrosome "HPA069748: AB_2686187" "unprognostic (6.98e-4)" "unprognostic (2.72e-2)" "unprognostic (2.40e-2)" "unprognostic (1.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.07e-2)" "unprognostic (9.88e-2)" "unprognostic (4.93e-2)" "unprognostic (3.34e-2)" "unprognostic (1.56e-2)" "unprognostic (1.88e-2)" "unprognostic (8.87e-2)" "unprognostic (4.06e-8)" "unprognostic (1.69e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" "unprognostic (5.98e-2)" 0.1 0.9 0.5 0.1 0.5 8.2 0.2 0.5 0.5 0.5 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.2 19.3 4.4 0.1 0.5 0.5 0.2 0.2 3.3 0.1 0.2 0.5 0.1 0.0 0.4 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.2 0.5 4.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 2.3 7.1 0.0 0.0 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.3 2.5 0.0 0.1 0.0 0.1 0.1 0.2 0.1 9.2 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.1 2.4 0.1 0.0 0.1 0.0 0.1 0.1 0.1 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.5 0.5 0.5 0.5 0.3 0.3 0.5 0.5 0.5 0.4 0.6 0.8 0.3 22.4 6.9 0.7 0.1 0.1 0.5 0.3 0.0 0.4 0.2 0.3 0.7 11.5 1.4 1.8 0.0 0.1 1.3 0.0 0.0 0.5 0.7 1.8 0.2 0.2 0.0 26.5 0.4 0.0 0.4 0.3 0.0 0.2 1.3 0.2 0.4 22.8 0.1 1.7 0.4 0.2 0.0 0.3 0.3 0.1 0.6 0.4 0.0 0.0 0.1 5.3 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.9 0.0 0.9 0.1 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 SEC14L6 ENSG00000214491 "SEC14 like lipid binding 6" B5MCN3 22 30522799-30546682 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 21.2;parathyroid gland: 30.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 10.5;Cholangiocytes: 11.5;Collecting duct cells: 12.9;Ductal cells: 6.6;Muller glia cells: 18.6" "Cancer enriched" "Detected in many" 7 "renal cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "K-562: 12.3;RPTEC TERT1: 21.8;SiHa: 6.6" HPA067695 Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA067695: AB_2685889" "unprognostic (3.49e-2)" "unprognostic (4.76e-2)" "unprognostic (4.79e-2)" "unprognostic (4.09e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (7.28e-3)" "unprognostic (3.88e-2)" "unprognostic (3.13e-1)" "unprognostic (3.35e-1)" "unprognostic (1.29e-1)" "unprognostic (9.25e-2)" "unprognostic (8.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (6.02e-2)" 1.4 1.4 5.3 0.3 4.6 2.1 3.9 4.5 4.7 3.5 5.9 0.5 0.6 3.2 21.2 0.3 1.7 4.5 0.3 4.4 5.0 8.4 0.4 11.9 0.4 8.6 6.2 2.4 5.5 30.5 2.5 0.5 8.8 1.7 0.3 5.0 0.4 2.6 0.2 10.0 0.5 2.2 5.2 0.4 1.2 5.4 8.7 0.3 0.3 0.8 0.6 0.4 0.4 4.9 0.2 0.1 0.9 0.3 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.2 0.5 0.3 1.1 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.0 3.0 0.3 0.3 0.1 0.2 0.4 0.0 0.1 0.1 0.1 0.7 0.0 0.1 12.3 0.2 0.0 0.5 0.1 0.4 0.5 0.0 0.1 0.2 0.0 0.1 21.8 0.2 0.2 0.1 6.6 0.1 0.0 0.2 1.8 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.3 0.1 0.5 0.1 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.3 0.1 0.1 0.5 0.0 5.3 4.6 4.5 4.7 4.4 5.0 8.6 6.2 8.8 5.2 8.7 4.9 0.0 12.8 10.5 0.3 0.2 0.1 0.5 0.0 0.0 0.2 0.4 0.5 0.3 11.5 3.7 12.9 0.0 0.0 0.0 0.0 1.9 6.6 0.0 0.3 0.4 1.0 0.0 0.0 0.7 0.8 0.0 0.2 0.0 1.5 1.3 0.2 0.7 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.6 18.6 0.0 1.5 0.6 1.8 0.0 0.7 0.0 0.1 0.0 2.9 0.0 0.5 0.0 2.7 0.1 0.9 0.4 0.0 0.0 0.1 0.9 0.0 0.0 0.2 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.6;intestine: 24.4;kidney: 18.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Muller glia cells: 35.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 53.6;Proximal enterocytes: 48.1;Proximal tubular cells: 24.6" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;CACO-2: 7.7;EFO-21: 14.6;K-562: 6.6;OE19: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA001220: AB_1078933, HPA077138: " "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 1.3 0.2 14.8 0.4 33.3 0.8 1.1 27.7 25.8 2.7 0.3 5.2 23.0 2.4 1.7 0.5 3.1 5.2 1.1 14.6 18.3 18.4 4.0 1.9 0.7 32.9 29.0 2.3 6.9 0.7 1.5 0.9 31.0 3.1 2.4 2.3 0.5 1.4 3.1 1.6 24.4 0.3 23.2 0.3 8.2 5.0 29.1 0.1 0.2 0.3 0.0 1.6 1.8 51.6 0.0 27.6 0.5 0.2 0.0 0.0 2.0 0.0 0.2 0.0 0.0 7.7 3.8 0.4 14.6 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.7 0.4 0.4 5.7 0.6 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.4 6.6 0.6 0.0 0.2 0.3 1.1 3.9 10.6 0.4 0.2 0.0 0.7 1.1 0.1 0.3 1.8 0.0 0.4 0.2 0.7 0.2 0.2 0.8 0.2 0.2 0.3 0.0 2.4 1.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.6 0.0 0.0 14.8 33.3 27.7 25.8 14.6 18.3 32.9 29.0 31.0 23.2 29.1 51.6 0.5 0.0 0.0 2.3 0.3 0.4 0.1 0.0 0.0 0.8 0.6 3.3 0.6 30.0 0.0 3.7 0.0 0.1 0.0 14.0 15.6 7.0 1.1 1.1 0.3 0.3 10.9 2.7 2.0 11.1 0.1 0.3 5.1 2.4 0.0 0.9 0.0 1.6 0.1 0.0 1.9 5.7 0.0 0.3 0.3 0.8 1.5 0.2 0.0 0.0 0.0 35.3 0.0 26.7 53.6 5.0 8.8 2.2 0.1 0.4 48.1 24.6 0.1 1.3 0.0 2.1 0.3 12.4 14.3 0.0 0.3 0.3 0.2 0.0 7.6 0.1 PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: AB_2676885, HPA062439: AB_2684764, HPA066670: AB_2685700" "unprognostic (1.82e-1)" "unprognostic (5.88e-2)" "unprognostic (5.59e-3)" "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.23e-3)" "prognostic unfavorable (1.84e-9)" "unprognostic (3.29e-2)" "unprognostic (3.40e-1)" "unprognostic (1.73e-1)" "unprognostic (4.79e-2)" "unprognostic (2.46e-2)" "unprognostic (5.65e-2)" "unprognostic (1.27e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-2)" "unprognostic (1.42e-1)" 33.3 41.0 26.3 29.2 28.6 35.5 32.2 26.7 30.5 31.8 27.1 29.6 21.7 35.5 21.2 43.6 29.4 20.2 28.8 26.9 26.2 38.7 48.2 26.2 32.3 27.1 27.2 34.2 57.3 30.1 21.8 21.5 27.6 32.9 19.6 9.2 29.3 21.5 48.8 45.3 28.2 22.5 25.8 34.4 35.7 40.0 27.0 23.8 27.1 20.0 27.3 35.0 31.9 30.0 132.2 146.6 53.0 113.7 59.9 58.4 81.6 84.7 69.6 141.6 110.0 170.6 55.2 177.2 74.4 97.0 110.3 89.4 163.9 153.5 103.1 76.4 159.8 85.9 80.8 149.0 149.3 209.6 86.8 82.7 94.7 148.3 147.3 68.3 93.0 62.4 144.6 69.9 87.7 164.3 102.6 209.8 103.1 128.3 106.7 129.0 91.7 173.3 78.9 88.7 91.4 94.6 84.2 94.6 117.8 42.0 66.8 106.1 74.2 165.9 126.1 85.3 145.1 88.1 81.0 178.6 116.2 94.9 109.0 7.5 24.9 6.4 18.9 29.8 23.2 20.2 17.4 18.1 26.8 20.0 19.4 18.0 0.9 20.0 22.3 23.2 14.3 29.3 26.3 28.6 26.7 30.5 26.9 26.2 27.1 27.2 27.6 25.8 27.0 30.0 23.6 3.2 18.9 4.9 17.4 22.6 23.4 32.7 22.2 6.5 14.1 12.2 3.8 24.3 22.1 25.8 8.4 34.9 7.8 19.6 25.4 48.0 44.4 11.7 13.8 23.2 23.4 24.6 4.3 43.9 40.0 15.4 22.4 10.6 18.3 24.4 27.8 22.8 38.4 3.3 4.3 22.4 22.4 27.8 12.6 14.3 19.9 21.2 21.4 2.8 29.0 13.5 16.5 6.6 5.1 38.7 16.2 20.3 28.3 26.4 31.3 55.1 24.6 8.9 19.7 23.2 20.7 28.7 20.9 25.9 22.9 28.5 13.5 19.9 29.7 15.1 TCN2 "D22S676, D22S750, TC2" ENSG00000185339 "Transcobalamin 2" P20062 22 30607003-30627271 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cobalt transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 105.0;Hepatic stellate cells: 137.4;Kupffer cells: 144.1;Proximal enterocytes: 563.6;Proximal tubular cells: 125.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 43.8;intermediate monocyte: 66.5;non-classical monocyte: 24.4" "Lineage enriched" "Detected in many" 8 "monocytes: 66.5" "Cell line enhanced" "Detected in many" "ASC TERT1: 117.6;HUVEC TERT2: 142.6;Karpas-707: 184.0;RPTEC TERT1: 70.7;TIME: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000837 Approved Cytosol "Secreted to blood" NA NA 19000000 "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA000837: AB_1080235" "unprognostic (6.43e-2)" "prognostic favorable (3.47e-4)" "unprognostic (1.53e-3)" "unprognostic (3.17e-1)" "unprognostic (1.49e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (2.64e-4)" "unprognostic (1.52e-2)" "unprognostic (2.90e-1)" "unprognostic (1.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.59e-1)" "unprognostic (6.95e-3)" "unprognostic (4.94e-3)" "unprognostic (2.09e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" 49.6 30.6 24.6 16.0 24.1 5.5 37.9 25.5 30.6 25.9 27.1 23.4 23.6 28.7 20.3 8.6 21.5 50.1 28.7 22.7 25.3 115.8 17.3 37.7 35.3 27.1 26.1 14.8 12.1 8.6 15.1 18.6 27.7 16.0 27.8 11.1 13.2 45.4 6.0 9.0 59.5 36.8 25.5 46.7 17.4 21.9 29.7 6.4 26.4 13.7 10.0 22.0 14.7 25.3 0.2 9.5 41.8 0.2 24.6 117.6 1.4 3.1 30.9 8.0 13.1 4.6 21.2 0.6 45.7 6.2 0.7 1.5 3.7 2.2 2.5 0.0 2.3 0.2 1.2 2.0 58.5 0.6 33.7 19.8 2.5 6.1 5.1 8.8 142.6 0.0 0.8 184.0 12.7 0.1 0.1 3.3 16.4 11.7 1.0 4.9 6.0 64.2 70.7 1.1 14.4 1.9 0.3 0.6 12.0 2.8 0.4 2.0 85.3 26.4 3.5 3.3 1.3 5.1 1.4 0.2 9.5 1.7 0.6 0.0 43.8 0.0 0.1 66.5 0.7 0.0 0.8 0.4 7.9 0.0 0.3 0.6 1.4 0.0 24.4 1.5 0.2 18.8 24.6 24.1 25.5 30.6 22.7 25.3 27.1 26.1 27.7 25.5 29.7 25.3 105.0 3.2 3.9 3.9 3.7 5.2 2.2 4.7 0.6 8.0 7.1 5.1 6.5 27.1 13.7 12.9 20.9 0.4 0.5 70.9 7.9 7.8 1.1 3.5 5.4 64.6 6.7 0.8 0.2 6.0 0.8 19.5 5.1 6.2 4.5 23.4 137.4 5.6 45.9 1.7 1.9 28.6 4.1 144.1 9.4 1.4 10.5 53.8 23.2 8.4 8.8 7.4 0.0 5.5 1.7 5.1 50.2 9.8 13.5 2.0 563.6 125.8 2.8 29.1 13.1 0.9 5.5 1.0 12.6 0.5 5.3 0.4 2.2 5.6 21.0 2.7 SLC35E4 ENSG00000100036 "Solute carrier family 35 member E4" Q6ICL7 22 30635781-30669016 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.9" "Group enriched" "Detected in many" 4 "Early spermatids: 122.2;Late spermatids: 108.6;Spermatocytes: 55.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HDLM-2: 22.8;U-2197: 21.0;U-87 MG: 22.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049558 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA049558: AB_2680817" "unprognostic (2.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.05e-1)" "unprognostic (1.01e-2)" "unprognostic (4.99e-2)" "unprognostic (2.04e-1)" "unprognostic (3.03e-4)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (1.76e-1)" "unprognostic (1.05e-2)" "unprognostic (2.39e-2)" "unprognostic (3.45e-7)" "unprognostic (2.77e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (8.05e-3)" 2.6 1.8 3.5 1.4 5.0 1.5 2.2 2.9 6.7 2.6 0.4 3.2 1.0 3.5 1.3 2.8 2.5 1.1 3.4 4.1 3.5 2.4 0.5 2.0 0.8 4.7 4.5 1.9 1.7 1.7 2.3 0.4 4.7 2.3 1.7 1.5 2.1 1.3 11.1 5.3 1.8 1.4 1.9 1.9 3.4 22.9 4.5 0.3 1.6 2.8 0.5 3.1 2.8 7.3 10.0 4.3 1.6 3.2 4.3 10.9 0.9 6.4 5.6 4.3 4.0 0.3 2.6 0.7 3.4 6.6 6.1 6.2 2.8 3.7 2.2 22.8 3.1 0.1 3.3 0.3 6.1 0.4 2.7 3.5 1.6 17.3 5.4 6.8 14.9 0.8 0.9 2.8 6.8 2.8 0.4 1.9 1.9 2.9 16.2 1.8 3.2 0.3 2.0 0.8 8.7 3.4 6.6 2.8 3.2 0.7 2.0 0.7 20.0 18.2 5.8 21.0 6.2 0.8 0.9 0.3 22.3 0.3 4.9 0.6 0.6 0.1 0.2 0.8 0.4 0.0 0.6 0.9 1.1 0.1 0.5 0.5 0.2 0.6 0.7 0.3 0.7 0.3 3.5 5.0 2.9 6.7 4.1 3.5 4.7 4.5 4.7 1.9 4.5 7.3 5.7 0.0 1.5 2.6 2.7 14.5 2.5 1.9 8.0 10.6 2.0 3.7 1.9 0.0 1.2 1.8 22.9 0.1 4.8 5.4 0.0 3.4 122.2 6.0 4.9 9.1 2.4 0.8 4.2 2.3 0.5 3.7 2.6 2.0 1.3 4.1 4.2 0.3 1.8 11.8 4.9 4.4 2.0 1.2 7.7 108.6 3.4 8.0 3.6 4.7 2.5 17.2 1.0 2.5 9.2 2.5 11.1 3.8 3.1 1.7 1.2 0.4 5.7 10.5 0.0 3.9 5.0 55.1 3.8 4.2 19.0 0.1 4.9 2.4 5.0 2.1 DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667887 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 123.4;Late spermatids: 344.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB034070: AB_2094867, HPA051349: AB_2681450" "unprognostic (1.11e-1)" "unprognostic (2.34e-2)" "unprognostic (3.49e-3)" "unprognostic (4.88e-3)" "unprognostic (1.88e-1)" "unprognostic (9.12e-2)" "unprognostic (3.77e-4)" "unprognostic (1.83e-1)" "unprognostic (1.61e-1)" "unprognostic (3.53e-2)" "unprognostic (9.62e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-3)" "unprognostic (6.55e-2)" "unprognostic (1.97e-1)" "unprognostic (4.56e-2)" "unprognostic (1.02e-1)" 3.3 1.9 3.4 4.5 3.6 3.3 2.8 2.9 5.3 2.4 9.1 5.4 5.0 2.9 4.9 4.1 10.9 4.2 2.0 3.7 4.0 2.2 1.0 5.5 4.7 5.4 7.6 2.4 2.9 3.3 4.2 2.1 4.9 2.1 6.8 5.2 2.5 2.4 1.3 4.8 4.6 3.8 4.8 4.3 4.8 13.9 4.5 4.0 3.3 1.6 3.9 3.3 2.6 6.0 5.4 5.4 2.5 5.8 6.2 11.9 2.3 4.9 5.3 4.7 5.1 3.1 5.3 3.6 3.3 6.0 6.2 3.8 1.3 3.8 5.3 9.8 6.1 1.5 2.2 2.2 2.6 7.4 5.3 3.1 5.4 7.8 3.0 5.3 15.0 4.1 1.7 2.8 5.2 4.8 4.2 1.8 0.8 6.4 3.3 2.8 1.7 1.2 5.6 3.7 6.2 3.7 4.8 1.7 3.5 3.2 4.5 2.2 11.1 9.9 5.4 2.7 2.8 2.1 2.6 1.7 11.4 1.3 5.0 31.4 15.3 29.9 8.6 19.3 6.6 9.7 9.6 7.7 17.2 8.7 6.6 7.5 31.8 7.4 21.4 9.7 13.2 8.4 3.4 3.6 2.9 5.3 3.7 4.0 5.4 7.6 4.9 4.8 4.5 6.0 7.2 19.2 5.4 11.4 7.1 21.4 13.3 6.5 2.2 2.9 4.9 3.4 2.0 10.0 9.6 5.5 45.9 1.2 12.0 10.0 3.9 10.1 123.4 34.5 5.0 10.1 35.5 2.1 8.0 9.4 3.9 6.8 8.6 5.0 7.0 4.4 13.9 1.1 8.1 1.7 4.4 15.4 6.1 15.6 28.5 344.2 8.4 13.2 8.8 13.1 13.9 10.1 9.2 1.5 14.3 9.3 15.4 6.8 3.9 8.8 24.2 4.1 64.6 16.8 6.6 8.6 6.6 63.0 17.2 5.7 21.3 1.0 9.7 3.5 19.0 8.7 OSBP2 "KIAA1664, ORP-4, ORP4, OSBPL1" ENSG00000184792 "Oxysterol binding protein 2" Q969R2 22 30693782-30907824 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.7;retina: 160.8" "Cell type enhanced" "Detected in many" "Early spermatids: 135.4;Excitatory neurons: 132.8;Inhibitory neurons: 156.3;Late spermatids: 304.4;Oligodendrocytes: 182.8;Rod photoreceptor cells: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 41.9;HeLa: 146.4;hTERT-HME1: 38.2;SiHa: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021514 Uncertain Approved Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol "HPA021514: AB_1854813" "unprognostic (2.89e-1)" "unprognostic (2.04e-1)" "unprognostic (2.83e-1)" "unprognostic (6.94e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (1.38e-5)" "unprognostic (3.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.79e-2)" "unprognostic (1.39e-1)" "unprognostic (2.31e-1)" "prognostic favorable (3.79e-6)" "unprognostic (9.00e-2)" "unprognostic (2.68e-1)" "unprognostic (2.93e-1)" "unprognostic (1.53e-2)" 1.4 11.8 6.2 2.8 14.4 52.7 1.5 17.0 20.5 1.6 2.1 1.7 7.5 2.0 14.6 3.7 2.0 3.0 12.2 8.5 4.4 2.6 1.0 1.6 2.3 9.6 9.8 1.6 5.0 9.3 20.9 4.6 10.0 2.3 1.7 160.8 2.9 2.4 2.8 5.4 5.6 1.2 1.8 4.8 3.5 28.7 21.3 0.6 3.2 3.2 1.3 4.4 2.1 15.1 7.1 15.4 1.5 6.7 1.0 5.8 1.6 1.3 3.1 4.8 4.8 14.0 3.9 12.5 5.7 1.9 1.5 4.1 6.2 0.6 3.5 6.7 1.8 41.9 146.4 2.7 0.9 0.2 2.5 0.3 16.8 11.8 38.2 1.6 12.1 4.8 26.7 0.5 11.0 7.8 1.3 4.5 3.8 3.3 13.8 3.5 0.5 0.7 0.6 2.7 16.7 6.8 39.2 4.1 0.4 2.9 4.9 2.2 8.8 3.4 18.1 3.2 6.8 3.2 4.8 2.3 13.3 0.0 2.7 0.0 0.7 0.4 0.5 1.1 1.0 0.5 1.0 0.4 0.6 0.6 1.0 1.1 0.7 1.0 0.9 0.2 0.7 2.0 6.2 14.4 17.0 20.5 8.5 4.4 9.6 9.8 10.0 1.8 21.3 15.1 1.2 0.0 3.1 37.9 0.2 5.2 0.9 0.4 0.6 93.2 1.3 0.8 11.2 2.8 1.0 1.8 81.3 0.2 0.3 1.3 1.9 1.8 135.4 1.6 0.5 2.8 7.2 91.3 132.8 1.5 0.2 1.6 2.0 1.6 0.0 3.2 0.4 0.1 0.2 18.5 156.3 2.8 0.0 0.3 1.8 304.4 2.5 1.7 1.8 8.4 0.4 31.4 0.0 35.7 182.8 0.8 5.2 1.9 1.4 1.2 0.7 0.8 1.3 619.5 0.0 1.1 2.3 48.6 4.4 1.4 9.5 0.3 0.5 1.2 1.2 1.3 MORC2 "AC004542.C22.1, KIAA0852, ZCW3, ZCWCC1" ENSG00000133422 "MORC family CW-type zinc finger 2" Q9Y6X9 22 30925130-30968774 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 5 "T-cells: 16.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000436, HPA077137" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "HPA000436: AB_1079404, HPA077137: " "unprognostic (3.43e-2)" "unprognostic (1.71e-2)" "unprognostic (1.60e-3)" "unprognostic (1.44e-2)" "unprognostic (6.15e-2)" "unprognostic (3.56e-3)" "unprognostic (2.89e-3)" "unprognostic (4.63e-1)" "unprognostic (6.76e-2)" "unprognostic (1.60e-1)" "unprognostic (5.46e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (6.54e-8)" "unprognostic (5.64e-2)" "unprognostic (2.38e-1)" "unprognostic (1.02e-2)" "unprognostic (6.66e-3)" 15.6 14.4 6.6 7.0 6.7 6.6 16.6 8.5 8.3 20.6 6.6 20.7 5.3 18.1 6.8 17.0 18.7 5.3 19.2 6.6 6.5 16.7 26.9 14.6 9.0 6.6 6.9 20.0 20.1 7.4 16.6 7.5 6.7 21.8 5.9 5.8 14.8 7.7 26.8 19.5 15.6 7.7 6.4 19.5 16.2 45.2 7.0 8.0 15.6 10.2 7.3 21.2 18.5 7.3 19.2 12.2 20.2 23.3 21.4 18.3 15.5 15.6 12.9 16.1 16.7 17.5 10.2 26.9 11.7 14.3 9.4 17.2 17.7 6.9 18.2 15.5 23.8 20.5 12.4 15.3 15.6 18.1 19.8 15.3 12.1 15.1 18.9 12.0 14.0 9.5 26.3 19.0 17.2 23.7 16.2 17.9 23.0 23.9 12.6 31.5 12.8 22.9 12.5 19.1 20.5 17.2 18.8 21.9 8.8 19.6 16.2 21.2 16.3 17.8 18.7 14.3 12.3 15.0 19.0 22.2 10.3 9.1 13.3 0.8 1.6 1.0 12.0 2.9 10.0 2.3 15.1 9.6 1.6 2.1 15.2 11.0 0.3 1.8 3.3 3.2 16.5 5.2 6.6 6.7 8.5 8.3 6.6 6.5 6.6 6.9 6.7 6.4 7.0 7.3 8.7 0.0 4.6 14.0 4.5 7.4 7.3 3.9 6.2 7.9 8.8 9.1 4.6 2.8 6.2 11.0 10.4 8.4 5.9 6.0 3.9 7.3 30.8 6.1 7.8 7.3 9.0 8.6 9.5 8.0 11.4 6.2 4.1 6.0 1.3 8.9 5.7 8.8 5.4 13.5 11.7 4.8 6.1 3.8 4.1 10.3 7.8 4.5 7.2 10.3 2.8 4.1 6.2 11.1 8.8 11.7 4.1 10.1 3.2 11.6 4.6 3.7 3.8 10.4 19.7 7.7 7.7 26.6 24.1 6.0 9.2 6.3 7.8 7.0 7.3 5.6 TUG1 "FLJ20618, LINC00080, NCRNA00080" ENSG00000253352 "Taurine up-regulated 1" 22 30969245-30979395 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" "unprognostic (2.83e-1)" "unprognostic (7.04e-2)" "unprognostic (1.87e-1)" "unprognostic (9.18e-2)" "unprognostic (8.34e-3)" "unprognostic (1.42e-1)" "prognostic unfavorable (4.37e-4)" "unprognostic (1.68e-1)" "unprognostic (2.89e-2)" "unprognostic (9.60e-3)" "unprognostic (3.98e-2)" "unprognostic (7.55e-2)" "unprognostic (1.50e-3)" "unprognostic (2.49e-1)" "unprognostic (1.93e-1)" "unprognostic (6.53e-2)" "prognostic favorable (8.27e-4)" 6.9 6.5 7.0 8.0 7.2 5.2 8.1 7.1 7.1 10.9 8.2 7.8 8.1 12.4 8.1 6.4 8.3 7.8 5.7 6.6 6.9 8.0 5.2 7.4 7.2 8.5 7.4 11.4 5.6 11.1 12.9 7.2 11.9 7.9 11.8 8.3 9.5 3.2 7.3 8.2 9.3 7.1 9.8 8.2 9.5 7.4 11.8 10.9 4.1 7.1 6.5 8.3 18.9 6.9 22.5 17.3 12.1 15.5 14.1 21.8 10.9 14.2 16.2 12.6 9.2 23.5 14.4 16.6 15.4 17.7 17.7 9.2 18.9 18.2 12.1 17.5 15.4 8.9 10.3 18.4 8.8 15.5 15.4 13.0 13.1 15.1 14.4 13.7 18.9 12.6 13.3 13.0 10.2 13.7 7.8 15.2 11.0 21.9 14.7 9.1 9.3 21.1 28.6 27.1 17.1 9.6 14.4 18.0 19.7 12.2 22.1 18.6 18.5 11.4 11.4 15.8 21.2 12.2 8.3 11.8 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 7.2 7.1 7.1 6.6 6.9 8.5 7.4 7.2 7.1 7.4 8.3 0.0 0.0 0.0 91.7 16.8 34.2 36.2 30.2 35.9 56.6 0.0 0.0 0.0 40.0 19.2 0.0 56.3 38.7 6.7 44.2 0.0 0.0 57.8 0.0 0.0 26.3 64.8 25.4 32.8 0.0 26.1 21.7 34.7 0.0 8.9 0.0 60.0 23.3 23.1 53.8 41.2 59.1 24.4 36.8 22.4 44.7 56.8 25.8 16.0 60.0 29.4 46.6 21.6 38.7 67.5 0.0 29.3 62.4 16.8 45.2 33.1 0.0 21.9 52.1 26.3 55.2 16.3 42.6 18.0 51.2 44.0 36.9 12.7 0.0 47.2 44.9 SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 887.2;urinary bladder: 450.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 283.5;Hepatic stellate cells: 121.3;Sertoli cells: 184.1;Smooth muscle cells: 116.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 200.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 140000 "Cluster 30: Non-specific - Translation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: AB_2681607, HPA058590: AB_2683765" "unprognostic (1.36e-2)" "unprognostic (4.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (1.08e-3)" "unprognostic (2.05e-2)" "unprognostic (4.56e-1)" "unprognostic (2.15e-1)" "unprognostic (7.22e-2)" "prognostic unfavorable (2.73e-5)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (8.41e-3)" "unprognostic (6.34e-2)" 54.7 19.2 10.8 25.3 12.5 4.7 42.2 10.3 13.1 100.2 7.6 887.2 30.0 251.0 7.0 65.1 132.4 20.8 152.0 9.0 9.3 35.6 15.3 38.2 5.6 11.7 12.5 34.0 25.2 3.3 9.8 17.4 11.0 150.9 29.2 15.2 16.3 177.9 95.7 38.7 151.5 127.2 10.5 54.5 231.2 12.5 12.4 2.9 26.4 26.2 2.5 450.6 91.5 10.0 73.0 21.2 7.2 27.0 11.0 17.2 58.0 106.8 49.1 85.7 58.4 29.9 22.4 32.1 9.3 59.3 17.3 10.6 7.2 62.8 40.4 10.6 58.2 33.9 18.3 36.1 9.7 51.5 57.4 14.2 5.8 114.0 18.7 29.2 74.7 12.3 37.3 25.9 59.6 64.5 5.9 11.4 8.2 36.1 90.0 20.3 20.5 34.6 34.5 23.2 11.5 12.7 33.4 15.9 15.7 7.4 18.8 8.2 118.7 62.1 58.4 59.4 79.8 24.6 32.5 18.8 91.0 19.7 200.5 0.0 1.0 0.0 0.1 0.2 0.0 1.3 0.1 0.3 0.4 0.0 1.0 0.5 0.1 0.1 0.2 0.2 0.0 0.6 10.8 12.5 10.3 13.1 9.0 9.3 11.7 12.5 11.0 10.5 12.4 10.0 94.5 6.4 3.3 23.8 2.0 65.1 33.5 16.1 19.4 46.6 18.6 26.7 39.5 5.7 6.1 9.2 283.5 13.4 2.7 12.8 9.8 14.8 1.2 4.0 52.1 62.8 29.2 0.0 0.2 20.1 68.8 35.9 18.3 7.3 0.0 11.0 121.3 2.6 6.0 5.0 1.9 29.9 14.2 6.8 14.6 1.9 22.4 4.7 14.2 7.5 1.0 31.2 1.0 4.5 2.0 73.2 11.4 48.5 2.1 21.7 5.6 18.4 2.2 54.0 184.1 18.4 116.4 5.7 7.9 9.7 69.3 21.9 3.7 16.3 27.0 14.9 SELENOM "SELM, SEPM" ENSG00000198832 "Selenoprotein M" Q8WWX9 22 31104772-31120069 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 373.6;Breast myoepithelial cells: 436.2;Collecting duct cells: 309.0;Distal tubular cells: 309.1;Endometrial stromal cells: 349.5;Exocrine glandular cells: 586.6;Smooth muscle cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 154.8;T-cells: 233.0" "Cell line enhanced" "Detected in many" "BJ: 152.2;BJ hTERT+: 143.8;HHSteC: 183.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008667, HPA019601" Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA 170000 "Cluster 20: T-cells - T-cell receptor" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Cytosol" "CAB008667: AB_1622762, HPA019601: AB_1856666" "unprognostic (5.29e-3)" "unprognostic (1.68e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.59e-3)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (1.60e-1)" "unprognostic (3.51e-3)" "unprognostic (8.31e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.32e-2)" "unprognostic (3.80e-1)" "unprognostic (5.20e-2)" "unprognostic (3.19e-2)" 241.8 95.4 126.7 55.7 126.7 2.9 239.8 127.3 170.7 458.8 189.9 575.4 37.2 600.2 14.8 86.1 437.8 28.6 227.2 130.0 149.3 162.5 36.7 157.5 25.9 137.1 138.6 262.4 154.3 94.7 241.1 32.2 131.0 339.6 16.4 8.1 198.8 140.1 109.9 114.8 193.9 85.3 139.6 97.6 285.6 42.1 142.1 10.2 225.8 18.6 15.3 462.3 290.7 132.3 12.8 25.7 7.4 42.7 68.8 80.5 82.2 152.2 143.8 69.2 50.0 0.8 2.0 1.6 30.9 89.9 31.2 1.2 6.9 9.2 4.7 7.0 25.6 2.7 7.8 13.3 183.7 0.0 13.1 78.5 27.1 33.1 12.6 33.1 9.0 2.2 2.4 14.7 17.9 6.6 0.5 1.4 9.6 11.8 27.3 0.1 0.1 18.1 11.1 0.1 16.2 35.7 47.3 41.6 0.7 2.5 57.5 0.9 30.9 20.8 59.0 77.8 0.1 13.2 6.5 1.0 83.1 0.2 13.8 18.3 10.5 5.1 105.3 19.9 137.9 154.8 174.5 127.0 6.4 129.5 233.0 137.8 8.2 39.1 40.1 2.5 179.0 102.6 126.7 126.7 127.3 170.7 130.0 149.3 137.1 138.6 131.0 139.6 142.1 132.3 168.6 54.5 126.5 0.0 38.8 0.0 0.0 0.0 0.0 0.0 373.6 436.2 0.0 0.0 32.2 309.0 0.0 11.7 23.2 0.0 309.1 101.2 0.0 22.8 349.5 61.8 0.0 0.0 0.0 586.6 149.5 161.3 0.0 18.1 30.3 30.8 0.0 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 42.9 0.0 0.0 0.0 0.0 166.2 0.0 0.0 22.3 0.0 0.0 152.5 20.4 0.0 0.0 0.0 225.6 0.0 0.0 0.0 0.0 23.4 24.8 30.5 0.0 0.0 INPP5J "INPP5, PIB5PA, PIPP" ENSG00000185133 "Inositol polyphosphate-5-phosphatase J" Q15735 22 31122731-31134697 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 123.2;thyroid gland: 204.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 35.0;Distal enterocytes: 24.0;Inhibitory neurons: 19.5;Muller glia cells: 25.2;Proximal enterocytes: 62.3" "Cancer enriched" "Detected in many" 6 "thyroid cancer: 63.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 19.6;SK-BR-3: 41.1;T-47d: 25.7;U-698: 18.1" "Region enhanced" "Detected in all" "olfactory bulb: 131.0" "Low region specificity" "Detected in all" HPA034539 Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoli fibrillar center" "HPA034539: AB_10670974" "unprognostic (1.76e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-1)" "unprognostic (7.05e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-2)" "unprognostic (2.21e-3)" "prognostic favorable (1.47e-5)" "unprognostic (6.81e-2)" "unprognostic (1.86e-2)" "unprognostic (4.29e-4)" "unprognostic (1.47e-1)" "prognostic favorable (1.12e-7)" "unprognostic (2.79e-3)" "unprognostic (3.65e-2)" "unprognostic (2.14e-1)" "unprognostic (1.39e-2)" 0.8 2.1 3.2 0.8 4.8 0.1 8.9 17.3 13.2 4.0 2.4 10.4 16.3 3.0 0.6 2.4 2.3 1.2 27.8 11.5 15.2 32.1 0.4 2.3 0.5 6.0 4.0 1.2 15.7 123.2 10.1 0.1 5.2 9.2 3.7 5.3 33.1 12.1 2.8 4.4 26.2 1.5 1.4 0.3 13.6 4.4 8.3 0.2 204.2 2.6 0.4 2.7 2.4 5.7 2.1 2.0 1.2 2.3 0.3 0.2 1.1 0.8 0.8 4.1 4.0 1.2 1.3 0.1 1.0 0.4 0.4 2.4 2.5 1.2 1.7 0.0 6.5 0.0 9.7 0.4 0.8 19.6 0.2 0.2 1.3 3.4 0.4 2.7 0.3 0.1 1.8 2.8 0.1 6.4 0.1 0.1 2.3 2.8 0.4 0.0 0.4 4.5 1.7 2.5 9.9 7.5 1.6 41.1 0.5 1.1 25.7 1.6 0.0 0.2 7.3 0.8 0.5 0.1 3.5 18.1 0.7 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 4.8 17.3 13.2 11.5 15.2 6.0 4.0 5.2 1.4 8.3 5.7 0.7 0.0 4.1 3.3 0.0 0.9 2.3 0.3 1.2 9.5 15.8 7.5 6.1 0.0 1.1 35.0 0.0 0.0 0.2 24.0 11.7 1.4 0.4 1.9 0.4 0.5 0.0 0.0 5.5 2.2 0.2 0.6 4.6 2.7 0.0 0.8 0.0 0.0 0.1 5.0 19.5 6.4 0.0 0.0 1.9 0.6 0.0 0.3 0.0 1.0 0.6 25.2 0.0 2.0 1.0 0.8 12.3 0.0 0.1 2.5 62.3 0.5 0.5 3.1 0.0 0.5 1.3 2.4 1.2 1.1 1.3 0.1 0.4 0.4 8.8 1.6 PLA2G3 GIII-SPLA2 ENSG00000100078 "Phospholipase A2 group III" Q9NZ20 22 31134807-31140508 "Enzymes, Metabolic proteins, Predicted secreted proteins, RAS pathway related proteins" "Cilium biogenesis/degradation, Lipid metabolism, Mast cell degranulation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 5.9;esophagus: 13.8;skin 1: 15.4;vagina: 7.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 3.6;Breast glandular cells: 7.5;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 3.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 15.1;AN3-CA: 15.3;NTERA-2: 7.8;SCLC-21H: 11.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA021016 Uncertain Uncertain "Endoplasmic reticulum,Golgi apparatus" "Secreted to blood" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Endoplasmic reticulum" "HPA021016: AB_1855443" "unprognostic (1.80e-1)" "unprognostic (4.63e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (1.74e-2)" "unprognostic (2.30e-1)" "unprognostic (4.25e-2)" "unprognostic (9.55e-3)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.29e-1)" "unprognostic (9.49e-3)" "unprognostic (3.72e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 1.2 0.8 0.2 5.9 0.7 0.1 0.3 0.0 0.0 13.8 0.0 0.0 0.0 0.4 0.1 0.5 0.0 2.5 0.0 1.6 0.1 0.0 0.0 1.0 0.1 0.0 1.7 0.3 0.0 0.0 1.8 0.3 0.2 15.4 0.2 0.0 0.1 0.0 0.6 0.5 0.1 0.1 0.6 0.0 1.7 0.0 7.1 0.2 0.0 0.0 15.1 15.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 1.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.2 0.4 0.1 1.6 0.1 1.7 0.1 0.1 0.2 0.0 0.0 3.6 1.6 0.0 1.3 0.2 0.2 0.0 0.0 7.5 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 17.8 0.0 0.0 0.0 0.0 0.4 RNF185 FLJ38628 ENSG00000138942 "Ring finger protein 185" Q96GF1 22 31160182-31207019 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.33e-1)" "unprognostic (3.65e-3)" "unprognostic (4.76e-3)" "unprognostic (2.60e-3)" "unprognostic (1.12e-2)" "unprognostic (3.97e-1)" "unprognostic (2.56e-1)" "unprognostic (2.61e-1)" "unprognostic (9.41e-2)" "prognostic favorable (4.82e-5)" "unprognostic (3.04e-1)" "unprognostic (1.63e-1)" "unprognostic (2.86e-1)" "unprognostic (1.10e-1)" 19.8 18.7 21.5 14.4 22.5 10.1 22.8 21.7 25.1 22.3 22.5 23.4 20.5 22.5 25.1 25.9 23.0 16.4 21.1 22.5 22.1 36.2 48.4 19.0 16.2 21.7 22.0 26.1 19.2 48.8 15.8 21.0 22.0 38.2 22.2 16.5 30.2 28.7 23.4 29.9 21.9 25.6 21.9 16.6 21.7 10.8 23.2 21.0 52.0 25.5 21.3 24.2 23.0 23.6 23.7 13.8 26.1 29.9 51.8 34.5 24.9 27.7 53.3 37.2 50.2 15.6 11.1 22.5 15.2 49.3 32.8 14.6 25.3 28.6 38.1 22.6 27.5 9.8 13.2 19.1 72.5 24.1 14.6 37.1 100.8 26.2 60.2 34.0 31.7 23.5 11.7 26.2 45.2 16.8 20.8 13.5 11.7 48.8 15.2 21.1 26.1 26.5 27.0 20.4 11.6 23.4 20.2 26.5 41.0 26.7 18.4 15.8 22.2 26.1 18.7 30.9 13.6 36.2 31.6 28.4 34.5 15.1 21.4 16.9 15.7 9.0 12.2 15.8 13.6 10.0 12.4 13.8 13.3 8.2 12.5 11.5 22.3 16.9 13.7 4.9 14.6 14.8 21.5 22.5 21.7 25.1 22.5 22.1 21.7 22.0 22.0 21.9 23.2 23.6 9.3 22.4 12.6 10.7 8.8 9.1 10.3 10.0 9.6 11.0 14.2 10.8 5.5 20.0 11.5 18.4 8.4 13.0 11.3 16.4 21.5 15.1 19.0 8.9 8.2 8.5 16.8 5.0 14.0 14.9 23.2 10.9 8.2 10.3 5.7 8.4 23.2 28.9 14.2 8.4 17.3 15.8 14.2 8.8 7.5 18.3 7.5 10.5 8.8 10.3 10.7 11.9 7.2 13.6 22.5 15.5 12.7 15.8 6.8 14.5 17.7 22.9 12.4 7.8 6.6 9.5 9.3 7.4 9.8 10.6 10.7 37.2 7.2 6.0 7.8 9.8 LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 115.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.0;neutrophil: 96.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 96.9" "Cell line enhanced" "Detected in all" "BEWO: 135.5;hTCEpi: 251.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "CAB019313: , HPA008183: AB_1079252, HPA053882: AB_2682291" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (1.04e-2)" "unprognostic (2.59e-2)" "unprognostic (1.39e-1)" "unprognostic (2.42e-2)" "unprognostic (4.02e-2)" "unprognostic (5.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.95e-1)" "unprognostic (3.96e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (4.57e-6)" "unprognostic (4.48e-2)" "unprognostic (1.48e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-1)" 20.1 14.4 25.5 39.8 27.3 53.8 30.9 25.8 22.1 26.4 32.6 34.0 21.2 17.0 7.7 71.8 34.2 21.3 14.3 20.8 27.7 27.7 33.0 46.8 23.2 37.8 34.2 21.6 28.8 27.0 21.9 48.0 32.8 36.7 34.7 25.5 50.7 19.1 18.8 71.5 29.3 15.9 32.7 37.5 30.0 19.2 33.6 21.3 42.0 9.2 17.8 25.7 45.3 33.1 26.6 4.4 17.9 10.0 7.6 8.8 135.5 17.2 8.0 16.9 14.2 22.7 12.2 25.8 29.9 26.0 8.1 52.6 20.9 90.3 10.6 19.1 22.8 18.8 21.1 24.7 11.4 35.1 33.1 14.3 251.5 13.7 41.0 114.5 43.6 20.6 10.7 18.2 23.3 20.9 21.5 12.0 16.7 68.3 6.7 28.1 30.0 14.3 19.6 62.3 22.8 20.4 13.0 82.1 35.1 54.8 68.7 13.9 26.6 15.1 23.5 8.3 16.3 10.0 16.2 22.4 9.6 16.4 6.6 5.8 5.1 40.0 3.1 3.5 5.9 2.0 5.7 4.3 1.9 2.4 5.6 4.4 96.9 6.7 1.4 4.4 15.2 4.4 25.5 27.3 25.8 22.1 20.8 27.7 37.8 34.2 32.8 32.7 33.6 33.1 19.5 32.1 17.9 16.3 5.2 35.9 37.7 24.8 59.2 9.4 18.0 23.2 25.1 10.0 32.6 5.5 20.9 69.8 15.3 39.3 3.9 13.0 1.4 49.6 19.2 22.4 13.2 10.3 6.4 45.0 52.4 7.6 48.9 41.6 23.5 8.6 14.3 7.1 18.2 3.3 11.3 42.8 18.3 8.9 8.2 1.6 4.4 13.8 3.6 16.9 5.4 16.6 2.1 2.5 15.5 25.9 21.2 4.5 6.2 27.1 12.0 10.5 36.3 22.8 19.7 7.5 17.2 15.6 18.4 46.1 39.1 115.5 9.3 7.1 51.7 29.9 PIK3IP1 "HGFL, MGC17330, TrIP" ENSG00000100100 "Phosphoinositide-3-kinase interacting protein 1" Q96FE7 22 31281594-31292534 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 499.2" "Lineage enriched" "Detected in all" 6 "T-cells: 499.2" "Cell line enhanced" "Detected in many" "RT4: 24.1;SK-BR-3: 26.1;U-698: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA Yes 6800000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "unprognostic (1.02e-1)" "unprognostic (1.97e-3)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (8.19e-2)" "unprognostic (1.61e-3)" "unprognostic (5.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (9.95e-3)" "unprognostic (1.28e-2)" "unprognostic (2.65e-3)" "unprognostic (4.42e-2)" "unprognostic (8.68e-2)" "prognostic favorable (3.80e-4)" 51.2 41.7 35.4 59.3 42.5 41.7 39.5 38.3 40.2 21.4 23.7 35.5 17.5 34.9 13.2 21.7 24.1 27.0 34.8 33.4 39.3 27.6 9.3 45.7 109.8 53.5 40.4 22.8 11.3 16.9 15.1 25.3 48.5 27.1 15.5 11.4 52.4 31.7 20.9 58.2 61.6 22.9 43.8 71.3 24.7 20.3 42.4 68.2 37.6 16.1 79.7 34.8 27.1 52.7 0.5 0.2 0.8 0.1 11.8 20.4 0.9 3.1 9.7 0.2 1.1 0.3 20.4 15.9 11.4 4.9 1.3 13.4 0.1 5.8 0.2 2.6 1.9 0.5 2.3 2.2 4.0 1.1 0.7 20.0 8.3 0.2 0.1 18.9 6.4 2.3 0.9 19.6 1.5 1.3 0.1 2.5 0.9 1.8 0.4 1.2 0.8 11.9 5.1 24.1 1.2 2.6 1.0 26.1 1.2 10.7 2.1 2.3 20.0 0.0 4.5 0.2 0.0 8.9 4.1 34.7 0.5 2.8 0.4 46.0 18.4 16.5 79.7 22.8 95.5 38.2 207.1 113.7 5.9 79.3 499.2 318.3 7.6 59.2 34.2 2.6 257.0 214.7 35.4 42.5 38.3 40.2 33.4 39.3 53.5 40.4 48.5 43.8 42.4 52.7 26.1 44.8 12.3 17.6 63.7 10.3 19.0 44.6 5.7 29.9 15.5 11.3 11.3 10.0 36.9 31.3 10.4 30.7 89.8 8.3 1.9 50.2 1.6 10.6 10.3 20.9 8.4 12.0 6.5 10.5 3.7 23.8 10.7 24.4 30.4 10.1 32.9 2.0 45.1 6.7 8.6 13.1 32.6 42.5 11.4 3.8 24.5 40.3 12.4 9.4 19.2 82.0 74.2 9.5 25.1 51.7 8.6 30.9 33.1 23.4 19.8 7.9 25.1 9.2 6.6 10.2 14.6 16.5 32.3 4.9 11.5 12.3 143.6 27.4 10.1 60.0 PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "HPA047893: AB_2680201, HPA048315: AB_2680353" "unprognostic (3.25e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (8.34e-3)" "prognostic favorable (8.71e-5)" "unprognostic (1.14e-1)" "unprognostic (1.41e-2)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "prognostic favorable (8.54e-8)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" "prognostic favorable (7.79e-6)" 10.2 10.5 16.0 11.4 18.1 15.8 12.1 16.4 16.1 14.5 11.1 14.8 9.9 18.7 14.2 6.1 22.2 9.3 10.8 14.7 16.0 11.6 11.8 11.2 20.3 18.4 16.7 27.3 13.5 21.0 10.5 9.3 17.6 13.1 6.9 14.9 18.7 17.0 10.5 7.9 12.7 12.2 17.1 15.7 11.1 8.1 16.4 24.0 19.3 8.5 14.8 15.7 9.7 20.4 19.0 23.3 46.7 27.7 12.1 11.1 24.5 5.7 14.2 22.6 20.6 16.5 17.7 40.1 20.1 10.6 7.9 14.5 32.0 17.3 11.5 23.7 29.5 16.9 16.7 33.8 19.7 57.4 21.9 17.4 20.5 14.4 16.0 17.8 18.0 19.4 7.3 15.7 14.6 57.7 37.1 39.3 31.4 34.4 27.1 61.9 19.9 13.3 15.3 39.4 60.8 48.7 14.2 17.1 31.4 15.4 33.8 36.2 12.8 15.1 28.3 9.5 19.5 20.3 14.4 36.5 6.3 7.5 26.3 0.0 1.0 2.8 1.8 0.6 1.8 2.5 1.3 2.3 1.4 1.8 2.9 2.2 0.4 2.1 0.3 4.0 2.2 1.2 16.0 18.1 16.4 16.1 14.7 16.0 18.4 16.7 17.6 17.1 16.4 20.4 6.6 3.2 14.9 11.4 12.8 1.7 7.1 7.6 8.0 16.8 22.0 16.0 13.7 17.2 11.7 20.2 8.4 5.2 17.0 3.3 19.6 14.3 0.6 14.9 8.8 7.6 20.4 8.0 2.4 6.2 2.0 6.4 5.6 16.7 6.3 19.3 7.1 16.2 9.4 21.9 5.0 9.7 20.3 8.1 2.6 1.7 9.6 6.6 3.6 7.5 7.7 14.4 12.3 11.1 8.8 6.4 6.0 8.6 5.5 7.4 5.0 7.1 10.5 14.3 6.6 7.1 8.5 0.7 8.1 2.3 1.6 0.8 10.4 8.4 11.8 7.3 DRG1 NEDD3 ENSG00000185721 "Developmentally regulated GTP binding protein 1" Q9Y295 22 31399604-31530634 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 160.2" "Group enriched" "Detected in all" 5 "Early spermatids: 798.4;Late spermatids: 651.5;Spermatocytes: 469.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001218 Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 22000 "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear bodies" Cytosol "HPA001218: AB_1078704" "unprognostic (4.94e-1)" "unprognostic (3.33e-2)" "unprognostic (1.17e-3)" "unprognostic (5.26e-2)" "unprognostic (4.66e-2)" "unprognostic (3.49e-3)" "prognostic unfavorable (7.71e-4)" "unprognostic (3.68e-2)" "unprognostic (1.54e-1)" "unprognostic (2.32e-3)" "unprognostic (8.69e-3)" "unprognostic (1.55e-3)" "unprognostic (4.80e-2)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (3.89e-1)" "unprognostic (2.25e-1)" 31.4 32.6 22.6 21.4 23.9 32.3 35.1 27.0 31.6 27.3 22.8 24.7 22.6 27.8 38.7 27.4 32.7 19.5 44.6 23.7 24.6 35.9 37.9 20.9 29.2 23.9 23.7 35.0 34.1 38.4 18.6 35.7 25.0 25.0 30.0 30.1 30.5 28.8 100.5 23.7 21.3 34.1 24.5 20.1 24.2 160.2 22.7 40.4 34.5 85.1 38.3 30.8 20.6 26.4 80.3 61.3 73.9 63.3 64.4 75.2 61.5 70.2 81.7 125.7 104.4 100.3 38.3 111.2 38.6 86.9 60.3 64.5 128.5 82.8 134.4 52.0 152.0 71.9 64.9 99.6 91.4 174.2 65.1 65.6 60.9 103.7 152.9 64.6 87.5 61.6 93.9 48.1 97.2 88.0 75.7 88.4 62.1 114.0 65.9 98.7 118.9 97.3 82.1 68.6 80.8 50.4 78.5 79.8 107.2 70.8 59.7 77.2 50.6 57.7 79.3 59.1 81.3 67.2 78.5 108.6 57.0 77.7 77.4 25.0 43.3 46.0 34.3 49.7 39.6 53.6 36.6 43.0 45.2 39.4 40.5 39.8 9.8 46.7 37.5 39.6 50.9 47.0 22.6 23.9 27.0 31.6 23.7 24.6 23.9 23.7 25.0 24.5 22.7 26.4 22.0 19.2 15.4 3.9 29.4 38.6 40.8 77.2 29.6 18.7 27.2 27.2 52.4 35.8 37.6 27.6 25.0 126.4 20.6 22.5 64.6 56.4 798.4 23.7 24.4 34.4 11.4 37.8 10.3 45.4 104.5 33.2 21.4 21.1 33.7 27.1 35.7 36.9 60.4 15.2 11.2 31.0 48.8 31.1 24.0 651.5 35.8 22.9 17.8 7.5 39.2 27.6 33.0 9.5 11.1 42.7 27.0 37.2 27.1 48.7 42.9 60.3 28.7 18.4 59.2 35.4 36.1 469.3 92.1 33.1 32.1 117.1 25.5 26.2 41.0 45.3 EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.6;Late spermatids: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Enhanced Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA001619: AB_1078727, HPA002078: AB_1078728" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-3)" "unprognostic (1.30e-2)" "unprognostic (4.95e-2)" "unprognostic (9.92e-2)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.30e-1)" "unprognostic (1.92e-1)" "unprognostic (7.32e-2)" "unprognostic (2.45e-2)" 12.5 11.9 14.3 10.4 14.8 14.3 11.9 19.7 17.3 15.9 11.4 19.4 11.4 15.0 13.0 14.0 13.8 7.8 13.2 15.3 15.0 12.3 8.4 12.1 12.6 13.6 14.7 15.0 10.5 16.7 10.8 13.6 14.3 13.5 11.5 18.0 12.1 13.2 20.2 15.7 11.8 12.1 11.6 12.3 12.3 34.7 13.8 12.9 13.5 14.5 14.9 15.6 14.3 17.3 19.8 11.6 29.4 16.0 16.1 14.2 11.7 13.7 16.8 21.4 19.8 13.4 7.0 25.3 7.9 20.7 14.3 19.1 26.9 12.5 19.7 20.2 27.0 10.3 20.0 15.4 16.7 41.0 17.9 16.6 16.9 15.8 17.8 19.5 18.4 14.8 25.4 27.0 20.3 22.4 27.8 20.3 13.5 18.3 9.5 31.1 24.5 26.0 21.7 14.7 22.6 20.9 18.9 15.4 14.5 19.4 16.4 16.1 20.5 14.3 18.6 14.4 15.5 19.3 20.4 25.1 13.7 14.8 17.1 1.3 2.4 1.2 3.4 3.0 3.5 4.8 1.8 3.3 2.2 2.0 1.8 3.2 2.0 1.0 8.1 4.4 1.4 1.9 14.3 14.8 19.7 17.3 15.3 15.0 13.6 14.7 14.3 11.6 13.8 17.3 8.4 12.8 15.2 23.2 10.6 7.4 7.3 6.2 15.4 18.0 9.6 8.9 22.7 10.0 8.5 12.9 12.5 9.8 13.8 8.6 9.8 8.9 54.6 8.0 12.8 10.2 12.0 12.4 21.0 6.4 5.5 8.1 12.2 13.0 6.3 23.1 11.0 8.9 8.0 18.5 20.5 10.8 8.2 9.5 6.2 98.9 14.6 7.5 7.2 13.1 14.5 8.1 14.4 20.1 20.2 10.2 3.6 15.4 10.3 10.7 5.7 9.4 6.3 13.7 6.6 11.8 11.0 38.7 13.3 10.7 10.5 6.7 8.2 9.0 8.1 8.0 SFI1 "KIAA0542, PISD, PPP1R139" ENSG00000198089 "SFI1 centrin binding protein" A8K8P3 22 31488688-31618588 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 119.5;Rod photoreceptor cells: 68.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "unprognostic (7.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.71e-2)" "unprognostic (3.27e-2)" "unprognostic (1.73e-1)" "prognostic favorable (1.10e-4)" "unprognostic (9.82e-3)" "unprognostic (3.51e-2)" "unprognostic (2.56e-1)" "unprognostic (1.77e-1)" "prognostic favorable (5.80e-4)" "unprognostic (2.73e-1)" "unprognostic (2.22e-2)" "unprognostic (1.04e-1)" "unprognostic (1.80e-1)" "unprognostic (2.11e-2)" "prognostic favorable (1.31e-4)" 3.4 6.1 3.3 7.8 2.0 13.0 4.7 10.4 5.0 5.0 1.5 5.6 8.6 4.1 4.1 4.1 5.5 3.4 2.4 1.8 4.0 5.0 2.9 4.6 12.2 2.4 1.5 5.2 5.0 3.9 10.0 2.6 2.4 5.5 2.7 8.5 5.3 3.3 1.4 5.7 9.4 2.2 0.8 9.5 5.5 10.0 3.2 10.6 6.3 0.7 6.5 4.8 4.4 2.9 11.3 7.0 6.4 7.9 3.5 3.3 4.0 8.9 3.7 6.1 7.5 6.4 7.7 17.3 3.4 2.8 3.9 10.4 3.2 5.6 4.2 14.2 10.1 4.2 16.9 7.8 4.6 16.9 13.5 2.5 3.7 6.9 4.5 5.1 5.5 16.0 5.4 8.4 5.1 17.0 11.8 10.3 2.4 8.1 4.2 12.8 7.5 12.5 3.7 11.8 9.6 5.4 7.6 10.8 7.4 2.4 8.1 7.2 10.4 8.6 7.8 7.5 6.4 9.9 7.8 9.2 8.6 8.8 6.9 8.5 1.2 3.1 9.1 1.3 4.1 4.1 7.3 10.6 1.4 3.5 9.9 8.9 5.5 9.3 5.0 1.7 5.9 5.5 3.3 2.0 10.4 5.0 1.8 4.0 2.4 1.5 2.4 0.8 3.2 2.9 7.2 6.4 26.2 17.6 17.6 4.0 7.9 6.8 5.7 45.7 9.7 8.0 2.7 8.6 17.3 16.5 35.5 8.8 21.8 21.7 1.9 7.3 14.2 16.1 5.7 8.9 11.4 17.9 30.5 5.1 2.3 5.6 17.9 18.0 20.3 15.5 7.1 2.9 4.9 119.5 30.9 25.0 6.1 9.1 8.2 5.1 5.3 9.4 3.6 19.7 8.6 7.1 34.0 10.6 17.1 7.6 15.5 1.9 19.1 7.0 34.6 3.2 31.3 68.7 0.0 9.6 5.7 28.9 27.6 2.7 3.3 18.9 35.2 2.6 10.0 6.3 PISD "dJ858B16.2, PSDC" ENSG00000241878 "Phosphatidylserine decarboxylase" Q9UG56 22 31618491-31662432 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Decarboxylase, Lyase" "Cataract, Deafness, Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 223.5;Syncytiotrophoblasts: 245.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 80.7" "Low region specificity" "Detected in all" "HPA031090, HPA031091" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Cytosol" "HPA031090: AB_10600114, HPA031091: AB_10600893" "unprognostic (7.96e-2)" "unprognostic (5.41e-3)" "unprognostic (2.60e-1)" "unprognostic (8.31e-2)" "unprognostic (5.61e-2)" "unprognostic (4.55e-3)" "unprognostic (2.44e-3)" "unprognostic (8.13e-3)" "unprognostic (6.37e-3)" "unprognostic (1.23e-1)" "unprognostic (1.11e-3)" "unprognostic (1.70e-2)" "unprognostic (4.18e-3)" "unprognostic (1.91e-2)" "unprognostic (4.85e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.27e-5)" 34.1 13.7 6.7 12.2 6.3 18.7 16.0 14.3 9.8 7.4 7.5 8.9 8.8 10.1 4.8 7.3 10.8 7.1 7.3 6.1 7.5 18.9 6.3 14.7 8.4 7.0 6.0 7.6 9.2 5.0 12.6 19.9 6.8 9.0 2.0 3.5 7.5 5.3 5.3 7.8 7.8 3.2 3.8 18.0 8.2 20.3 7.2 3.8 11.5 3.2 4.3 7.3 7.1 5.1 21.7 19.7 5.8 5.8 17.3 6.6 13.2 17.4 13.6 11.9 12.9 28.6 6.6 12.9 18.0 8.8 15.8 24.0 7.9 15.5 1.9 14.4 16.9 13.5 12.8 23.7 35.9 28.7 34.2 12.4 8.5 21.2 9.1 4.9 10.6 9.0 40.3 7.6 6.9 80.7 12.5 12.4 5.7 14.2 8.1 17.4 6.5 13.0 7.6 18.9 14.2 8.4 10.1 31.8 11.0 4.7 26.5 15.5 21.0 14.9 17.7 9.6 16.3 8.9 13.3 16.2 14.2 19.0 12.1 24.1 21.7 16.1 10.6 15.8 10.3 11.9 7.7 9.0 18.3 11.9 10.3 8.6 47.0 10.4 8.7 8.9 8.2 13.8 6.7 6.3 14.3 9.8 6.1 7.5 7.0 6.0 6.8 3.8 7.2 5.1 11.1 16.0 15.6 17.3 12.4 25.6 34.7 31.5 38.7 26.0 18.6 12.6 55.5 12.8 31.1 42.3 20.9 223.5 12.9 12.0 11.7 33.2 60.0 36.2 17.9 19.6 20.9 32.4 40.3 16.8 25.9 13.6 17.3 87.3 18.3 13.2 8.9 7.5 36.4 18.5 35.5 12.9 22.4 36.4 12.7 81.9 9.6 19.8 3.6 9.4 27.1 11.8 24.7 16.1 19.9 15.9 8.4 7.2 11.4 52.1 12.3 13.9 10.9 25.8 19.7 4.9 11.1 25.0 17.9 27.7 21.3 245.0 11.8 8.3 14.2 43.5 PRR14L "C22orf30, MGC50372" ENSG00000183530 "Proline rich 14 like" Q5THK1 22 31676256-31750140 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062645 Uncertain Approved Nucleoplasm NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA062645: AB_2684817" "unprognostic (2.87e-1)" "unprognostic (1.34e-1)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (2.42e-2)" "unprognostic (2.13e-1)" "unprognostic (1.37e-2)" "unprognostic (4.10e-2)" "unprognostic (8.86e-3)" "unprognostic (1.80e-1)" "unprognostic (2.10e-1)" "unprognostic (4.90e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.48e-2)" "unprognostic (4.14e-3)" 3.8 3.6 3.1 5.4 4.1 8.6 5.6 5.8 3.8 4.5 8.5 6.3 4.3 4.3 4.2 5.7 5.1 3.3 3.2 3.5 2.4 4.3 4.2 4.5 6.9 2.0 2.1 6.9 4.1 6.6 4.7 5.3 1.9 4.0 7.0 4.9 4.2 3.7 2.8 6.9 4.7 5.0 0.6 5.6 5.9 5.5 3.7 7.6 5.3 4.6 7.2 4.8 4.0 6.5 11.4 10.8 11.6 11.5 10.4 9.7 12.0 6.1 7.2 9.4 8.7 9.9 4.1 12.9 5.8 12.0 7.0 11.0 22.9 9.1 9.7 17.3 9.7 7.8 9.7 8.0 8.8 24.3 16.2 8.7 9.0 13.0 11.2 8.1 13.3 10.1 12.0 8.3 9.9 10.8 8.6 7.7 13.4 16.3 4.1 12.8 18.5 7.4 7.8 12.8 16.0 9.4 14.2 8.5 7.8 13.6 7.5 9.6 12.7 5.7 11.4 7.7 8.4 12.8 16.4 9.5 8.9 11.7 8.9 9.1 4.3 5.4 2.9 5.1 2.6 3.5 1.8 2.4 3.3 3.1 2.6 2.8 8.1 2.9 11.8 3.7 2.7 1.8 3.1 4.1 5.8 3.8 3.5 2.4 2.0 2.1 1.9 0.6 3.7 6.5 18.1 22.4 20.3 31.0 18.1 7.5 13.4 18.5 16.5 11.9 16.0 12.3 22.2 10.0 28.7 11.0 20.9 19.0 21.1 29.5 9.8 19.3 7.4 25.9 27.3 16.2 10.2 14.3 48.0 17.1 14.2 15.6 25.0 24.4 26.6 56.6 11.7 18.4 14.6 15.2 38.8 19.4 10.2 21.3 9.2 5.9 14.9 21.2 1.8 35.6 24.7 12.1 20.6 21.6 46.7 24.6 13.9 8.2 12.4 19.3 20.3 11.9 23.2 11.7 13.1 21.9 15.6 14.0 18.4 19.9 9.7 22.2 14.4 27.9 18.5 20.3 DEPDC5 "DEP.5, KIAA0645" ENSG00000100150 "DEP domain containing 5, GATOR1 subcomplex subunit" O75140 22 31753867-31908033 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 31.9;Inhibitory neurons: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 34.8" "Cell line enhanced" "Detected in all" "U-698: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054969, HPA055619" Uncertain NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "HPA054969: AB_2682655, HPA055619: AB_2682864" "unprognostic (5.68e-2)" "unprognostic (1.16e-2)" "unprognostic (8.98e-3)" "unprognostic (8.83e-2)" "unprognostic (5.60e-2)" "unprognostic (7.87e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-2)" "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (4.59e-3)" "unprognostic (6.64e-2)" "prognostic favorable (2.46e-5)" "unprognostic (5.66e-2)" "unprognostic (7.88e-2)" "unprognostic (1.26e-1)" "prognostic favorable (4.86e-5)" 6.3 7.7 6.4 5.1 6.5 4.4 5.6 8.7 10.8 8.7 5.8 7.4 3.0 6.0 3.4 7.2 6.6 3.5 4.8 6.5 6.3 5.5 9.9 5.3 6.3 6.0 5.8 11.3 4.2 4.9 6.2 3.6 6.2 5.5 5.2 4.0 6.0 3.0 5.9 6.4 8.5 3.7 5.3 9.4 6.2 7.4 6.5 4.9 5.7 3.8 9.7 6.6 7.1 8.6 5.7 5.0 9.1 5.7 4.5 4.7 7.4 3.9 6.4 5.1 6.8 6.8 3.4 13.0 1.5 5.5 4.1 5.8 6.3 6.3 9.1 6.7 5.8 6.1 6.1 6.7 4.4 20.6 19.0 5.2 3.2 9.6 4.8 4.3 9.3 4.8 4.3 3.9 7.3 5.5 5.8 5.8 4.6 9.9 2.1 11.2 10.0 7.4 6.0 12.0 6.0 6.7 7.8 4.2 5.2 6.6 4.4 11.5 8.0 5.0 6.0 5.2 3.8 5.8 5.7 31.5 5.5 6.0 5.1 34.8 2.9 15.2 2.6 3.4 3.0 6.8 1.9 1.5 2.5 4.2 3.0 3.8 1.8 4.2 3.7 1.8 2.3 1.3 6.4 6.5 8.7 10.8 6.5 6.3 6.0 5.8 6.2 5.3 6.5 8.6 4.7 0.0 3.9 20.5 12.0 2.7 1.8 3.0 5.2 4.9 4.5 2.9 4.3 2.8 5.5 7.3 2.1 3.8 4.5 10.4 3.9 5.1 1.3 4.2 6.1 5.1 13.2 2.1 31.9 4.9 3.1 4.3 6.6 6.5 5.7 18.2 4.2 4.9 3.5 16.8 29.6 6.2 6.1 3.1 2.2 2.2 1.8 6.9 3.6 24.4 3.9 4.2 5.2 23.1 24.3 4.7 5.6 2.6 4.4 1.6 4.7 2.8 5.2 5.6 6.6 3.1 3.1 4.8 5.2 4.3 2.3 2.3 5.3 11.4 5.0 1.8 Z82190.2 ENSG00000285404 "Novel protein, DEPDC5-YWHAH readthrough" 22 31754899-31956243 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054969, HPA055619" Uncertain NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "HPA054969: AB_2682655, HPA055619: AB_2682864" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944522-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 501.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025918 Uncertain NA NA 42000000 "Cluster 26: Non-specific - Mitochondria" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "CAB025918: " "unprognostic (3.77e-1)" "unprognostic (6.13e-2)" "unprognostic (1.67e-2)" "unprognostic (1.86e-2)" "unprognostic (1.13e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.59e-5)" "unprognostic (8.62e-2)" "unprognostic (1.63e-1)" "unprognostic (4.51e-2)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.40e-1)" "unprognostic (1.59e-1)" "unprognostic (5.60e-2)" "unprognostic (7.00e-2)" "unprognostic (6.81e-2)" 104.9 82.7 244.8 87.2 309.8 86.8 76.6 96.2 501.2 54.6 4.6 106.3 64.8 68.7 92.8 60.4 73.1 82.4 78.1 386.6 217.9 77.6 61.4 112.2 68.3 156.7 109.2 53.0 69.6 29.5 64.4 100.0 145.9 57.8 111.1 114.1 59.4 70.9 68.7 65.0 68.9 131.0 74.1 57.9 109.3 16.2 118.1 70.4 62.0 54.8 82.4 89.9 58.3 229.8 344.5 142.4 180.8 91.8 112.7 107.0 97.0 321.9 172.0 208.1 228.6 157.8 124.2 202.8 76.6 329.4 116.6 169.1 208.7 183.7 271.4 177.0 157.7 118.7 108.2 156.8 108.5 391.4 132.8 84.9 113.0 176.9 135.6 137.3 201.3 76.9 171.5 155.6 249.6 148.5 121.0 189.8 185.2 197.1 150.8 173.7 201.2 115.1 216.5 153.1 323.5 104.4 184.2 134.7 124.7 245.9 78.2 119.3 248.4 206.0 190.1 138.2 216.6 80.7 130.5 257.7 137.3 162.0 170.9 11.9 19.8 22.0 7.6 16.8 11.1 12.4 9.4 10.8 22.9 13.0 3.7 4.9 11.6 25.4 18.4 6.2 19.5 14.0 244.8 309.8 96.2 501.2 386.6 217.9 156.7 109.2 145.9 74.1 118.1 229.8 259.0 51.3 21.7 27.1 106.6 334.1 223.5 27.3 125.2 54.8 123.6 79.0 51.2 125.8 26.5 126.9 22.9 171.7 53.0 242.8 232.8 148.0 3.9 180.0 81.1 211.7 75.4 269.8 132.0 160.6 145.4 118.8 139.1 153.0 40.0 33.4 120.3 72.1 245.6 53.8 62.9 125.4 34.6 155.6 269.8 13.7 61.2 397.6 300.6 66.5 102.1 80.1 44.3 22.1 42.0 203.3 115.7 80.9 120.4 240.7 93.4 125.5 52.5 73.7 157.8 55.8 197.1 23.3 35.5 164.1 340.0 34.8 95.2 25.7 116.1 191.8 SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 528.1" "Cell type enriched" "Detected in many" 6 "Proximal enterocytes: 768.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "OE19: 34.2" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" "Nuclear membrane, Cytosol" "CAB015467: , HPA051805: AB_2681618, HPA055106: AB_2682695" "unprognostic (1.96e-1)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "prognostic favorable (2.59e-4)" "unprognostic (3.85e-2)" "unprognostic (2.75e-2)" "unprognostic (1.60e-2)" "unprognostic (2.15e-1)" "unprognostic (9.22e-2)" "unprognostic (4.83e-2)" "unprognostic (6.21e-2)" "unprognostic (9.53e-2)" "prognostic favorable (6.97e-7)" "unprognostic (4.68e-3)" "unprognostic (1.98e-1)" "unprognostic (6.00e-2)" "unprognostic (1.45e-2)" 0.1 0.0 0.1 4.2 0.1 0.0 9.7 0.2 0.1 12.3 0.0 10.7 528.1 0.5 3.5 5.1 1.1 26.9 75.2 0.1 0.0 6.6 1.7 2.1 0.3 0.1 0.0 0.0 1.6 0.3 1.0 0.0 0.1 3.0 9.7 0.2 19.0 2.4 0.3 13.5 302.4 0.7 0.0 2.9 7.2 2.3 0.5 0.1 0.0 0.0 4.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 34.2 0.0 0.0 0.0 2.1 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.2 0.1 0.0 0.0 0.3 0.2 0.6 1.7 4.2 0.0 0.0 11.6 6.5 115.2 115.8 8.2 0.0 0.0 0.0 0.2 19.8 0.0 3.0 38.4 2.4 1.4 1.0 25.4 0.0 0.4 1.4 0.0 1.4 5.6 10.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 34.1 0.0 0.0 0.0 71.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 32.6 1.5 0.0 17.6 768.7 6.4 2.0 0.0 0.0 0.0 0.7 10.1 4.2 2.0 5.5 0.0 0.1 0.1 41.2 6.7 C22orf42 ENSG00000205856 "Chromosome 22 open reading frame 42" Q6IC83 22 32149006-32159322 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 13 "brain: 12.5;testis: 10.6" "Group enriched" "Detected in some" 8 "Early spermatids: 95.7;Late spermatids: 31.3" "Group enriched" "Detected in some" 5 "pancreatic cancer: 0.8;prostate cancer: 1.0" "Group enriched" "Detected in many" 4 "hypothalamus: 8.9;midbrain: 4.5;pons: 4.5;thalamus: 12.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019531 Enhanced NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 29: Early spermatids - Spermatogenesis" "HPA019531: AB_1853016" "unprognostic (5.67e-2)" "unprognostic (6.13e-3)" "unprognostic (8.21e-3)" "unprognostic (7.06e-2)" "unprognostic (4.54e-2)" 0.0 0.0 1.8 0.0 0.9 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.8 4.5 0.0 0.4 0.0 0.9 0.0 4.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 10.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.9 0.1 0.4 0.0 8.9 0.8 4.5 4.5 0.4 12.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.7 0.2 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 31.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 10.2;prostate: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 17.6;Inhibitory neurons: 8.6" "Cancer enriched" "Detected in single" 15 "prostate cancer: 5.6" "Region enriched" "Detected in many" 4 "cerebral cortex: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (3.81e-2)" "unprognostic (4.05e-2)" "unprognostic (8.29e-2)" "unprognostic (9.66e-3)" "unprognostic (2.54e-1)" "unprognostic (9.90e-2)" "unprognostic (2.59e-1)" "unprognostic (6.02e-3)" "unprognostic (2.22e-2)" "unprognostic (3.44e-2)" "unprognostic (8.64e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.04e-4)" "unprognostic (6.02e-2)" "unprognostic (3.28e-2)" "unprognostic (5.62e-7)" "unprognostic (3.50e-2)" 0.0 0.5 1.5 0.0 1.9 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 0.0 0.1 1.7 0.7 0.3 0.0 0.0 0.1 0.0 1.7 3.8 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 10.2 2.3 0.9 1.7 0.7 1.7 0.0 1.0 1.6 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.7 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 SLC5A4 "DJ90G24.4, SAAT1, SGLT3" ENSG00000100191 "Solute carrier family 5 member 4" Q9NY91 22 32218464-32255347 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 19.8" "Group enriched" "Detected in some" 11 "Excitatory neurons: 28.1;Inhibitory neurons: 20.5;Microglial cells: 31.9;Oligodendrocyte precursor cells: 9.5" "Cancer enriched" "Detected in some" 10 "melanoma: 7.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "SK-MEL-30: 27.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (1.93e-1)" "unprognostic (1.57e-1)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (1.28e-2)" "unprognostic (2.85e-3)" "unprognostic (2.97e-2)" "unprognostic (3.80e-2)" "unprognostic (3.58e-2)" "unprognostic (1.06e-1)" "unprognostic (2.65e-3)" "unprognostic (4.50e-1)" "unprognostic (1.99e-5)" "unprognostic (2.34e-1)" "unprognostic (1.63e-1)" "unprognostic (2.28e-1)" "unprognostic (2.69e-1)" 0.7 0.2 0.1 0.1 0.1 0.1 0.8 0.4 2.9 1.2 0.0 0.1 17.6 0.8 0.3 0.2 0.7 0.6 0.6 0.6 0.0 0.7 0.2 1.5 0.2 2.1 0.0 0.3 0.4 0.3 0.1 0.0 2.7 0.5 0.1 0.1 0.2 0.3 0.1 0.3 19.8 1.4 0.0 0.3 0.2 0.4 0.3 0.0 1.3 0.0 0.1 0.4 0.7 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 27.8 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 2.9 0.6 0.0 2.1 0.0 2.7 0.0 0.3 0.7 0.9 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 28.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 31.9 0.1 0.0 0.0 9.5 1.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 24.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Spermatocytes: 2.0;Spermatogonia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.6;NB-4: 2.2;U-266/70: 2.5;U-266/84: 2.6" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (1.63e-1)" "unprognostic (9.90e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.25e-2)" "unprognostic (4.31e-2)" "unprognostic (1.90e-1)" "unprognostic (6.32e-2)" 0.1 0.1 0.0 0.2 0.1 1.4 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.5 0.7 0.0 0.1 0.1 0.1 0.3 0.0 2.4 0.5 0.0 0.5 1.3 0.3 0.0 0.0 0.7 0.1 24.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 1.0 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.8 0.0 0.4 0.6 2.2 0.1 0.1 0.0 1.1 0.2 0.3 0.0 0.2 0.8 0.1 0.0 0.2 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 2.5 2.6 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 BPIFC "BPIL2, dJ149A16.7" ENSG00000184459 "BPI fold containing family C" Q8NFQ6 22 32413847-32464484 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 63.6" "Cell type enhanced" "Detected in some" "Early spermatids: 22.8;Late spermatids: 9.8;Suprabasal keratinocytes: 4.7" "Group enriched" "Detected in some" 11 "head and neck cancer: 1.6;melanoma: 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 22 "basophil: 2.1" "Lineage enriched" "Detected in single" 22 "granulocytes: 2.1" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (2.74e-1)" "unprognostic (3.48e-3)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (2.58e-1)" "unprognostic (3.48e-2)" "unprognostic (2.74e-1)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (1.41e-2)" "unprognostic (2.80e-1)" 0.1 0.0 0.2 0.0 0.1 0.0 3.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 63.6 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.2 0.0 0.0 1.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 9.8 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 4.7 0.0 0.0 0.0 0.0 0.0 FBXO7 "Fbx, FBX7, PARK15" ENSG00000100225 "F-box protein 7" Q9Y3I1 22 32474676-32498829 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 279.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 680.9;Late spermatids: 620.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032113, HPA032114, CAB034296" Uncertain Supported Nucleoplasm,Cytosol NA NA 550000 "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Cytosol" "CAB034296: AB_2102563, HPA032113: AB_2674156, HPA032114: AB_10696202" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.36e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.03e-1)" "unprognostic (2.45e-2)" "unprognostic (2.28e-1)" "unprognostic (2.53e-1)" "prognostic favorable (2.66e-10)" "unprognostic (3.33e-2)" "unprognostic (1.65e-1)" "unprognostic (7.02e-2)" "unprognostic (1.79e-3)" 51.6 61.7 70.3 35.9 86.8 279.9 52.9 79.9 86.5 53.5 72.3 53.5 47.7 49.2 68.7 40.1 66.6 43.9 38.5 68.3 76.2 106.5 128.4 59.6 54.6 85.0 83.8 62.7 41.0 75.9 50.6 71.5 84.1 42.6 53.8 40.1 43.1 53.5 31.0 50.6 48.4 57.1 79.0 65.6 48.4 99.5 79.8 77.9 134.2 48.3 61.8 54.8 44.0 97.8 72.1 52.1 69.3 77.1 105.8 99.5 45.9 64.3 119.6 102.7 121.9 54.4 51.1 71.2 49.6 114.6 87.8 47.6 103.3 84.7 105.1 111.8 80.9 99.1 54.4 83.7 126.8 126.2 82.8 83.8 134.1 90.6 69.2 93.4 112.2 53.1 77.5 88.0 112.7 57.7 65.3 81.2 26.7 102.3 36.1 64.1 72.2 84.0 118.2 81.0 96.6 63.1 81.3 62.4 235.2 98.3 34.0 67.2 76.0 50.6 69.4 48.4 49.5 62.1 69.3 67.6 97.4 65.6 212.3 251.5 59.9 132.1 83.3 70.6 101.5 70.2 75.9 84.9 82.2 63.6 65.6 72.6 22.4 98.3 74.9 55.8 101.3 90.4 70.3 86.8 79.9 86.5 68.3 76.2 85.0 83.8 84.1 79.0 79.8 97.8 48.8 41.7 25.3 37.9 60.4 46.3 69.4 72.7 48.9 26.0 46.5 32.3 16.1 65.8 48.1 49.7 18.8 90.2 73.6 43.4 97.8 75.3 303.3 41.3 37.8 53.1 67.6 680.9 27.6 77.4 108.9 47.9 40.2 47.2 55.8 63.6 53.9 88.6 71.9 33.7 26.7 42.7 65.1 64.8 53.2 620.8 45.1 55.0 119.2 28.1 125.2 54.1 72.1 101.0 170.6 77.2 58.0 48.9 62.7 68.3 72.2 152.9 34.2 38.1 46.0 35.3 46.2 149.4 136.9 42.3 43.3 71.6 62.3 41.8 47.2 83.7 SYN3 ENSG00000185666 "Synapsin III" O14994 22 32507820-33058381 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 25.0" "Cell type enhanced" "Detected in some" "Early spermatids: 54.5;Excitatory neurons: 347.7;Inhibitory neurons: 198.6;Late spermatids: 250.7;Oligodendrocyte precursor cells: 75.9" "Cancer enhanced" "Detected in some" "testis cancer: 1.0" "Region enhanced" "Detected in many" "cerebral cortex: 25.0" "Immune cell enhanced" "Detected in some" "naive B-cell: 3.2" "Group enriched" "Detected in many" 11 "B-cells: 3.2;granulocytes: 1.6" "Cell line enhanced" "Detected in many" "A-431: 15.0;EFO-21: 12.5;NTERA-2: 7.0;PC-3: 9.0;SCLC-21H: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA034566 Uncertain NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA034566: AB_10603120" "unprognostic (1.15e-2)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-2)" "unprognostic (5.13e-3)" "unprognostic (2.34e-1)" "unprognostic (9.39e-2)" "unprognostic (3.24e-1)" "unprognostic (7.77e-2)" "unprognostic (8.91e-2)" "unprognostic (8.59e-2)" "unprognostic (7.44e-3)" "unprognostic (4.35e-3)" "unprognostic (1.80e-2)" "unprognostic (1.40e-1)" "unprognostic (3.40e-2)" "unprognostic (3.52e-1)" 0.7 0.8 12.4 0.6 0.0 2.5 0.6 0.0 25.0 0.3 0.0 0.7 0.6 0.6 0.6 1.5 0.7 1.0 0.6 6.8 0.0 0.8 0.5 0.8 1.2 3.6 0.0 0.4 1.2 0.4 1.6 2.6 6.4 0.6 0.6 4.1 0.5 0.4 0.5 1.8 1.0 0.6 0.0 1.4 0.8 3.9 0.0 0.7 0.9 0.4 0.6 0.3 0.2 0.0 15.0 0.7 0.4 1.9 0.0 0.4 0.6 0.5 0.1 0.0 0.2 1.4 1.1 0.7 12.5 0.1 6.2 3.6 5.4 0.1 0.0 0.3 1.1 0.7 5.1 3.0 0.0 0.9 0.6 0.2 1.0 0.1 0.0 0.3 0.1 0.3 0.9 0.6 0.0 0.1 0.6 0.5 7.0 0.2 9.0 0.4 0.6 0.6 0.0 1.0 7.4 0.6 1.2 0.1 1.2 3.3 0.2 0.4 0.4 0.7 4.8 1.0 1.0 0.5 0.7 0.6 0.4 0.4 2.8 0.9 0.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 0.0 1.6 0.1 0.2 0.1 0.0 0.1 12.4 0.0 0.0 25.0 6.8 0.0 3.6 0.0 6.4 0.0 0.0 0.0 1.6 0.0 0.0 8.5 1.5 0.4 0.1 0.0 0.0 3.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 54.5 0.1 0.4 0.9 0.0 0.0 347.7 0.0 0.6 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.3 5.0 198.6 0.0 0.0 0.0 0.5 250.7 1.5 0.1 0.0 12.2 0.0 0.0 0.0 75.9 8.1 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.6 6.6 0.0 0.9 3.7 9.0 0.0 0.1 1.1 0.0 0.7 0.0 0.0 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 LARGE1 "KIAA0609, LARGE" ENSG00000133424 "LARGE xylosyl- and glucuronyltransferase 1" O95461 22 33162226-33922841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Glycosyltransferase, Multifunctional enzyme, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 8.5;Alveolar cells type 2: 8.2;Ductal cells: 7.1;Endometrial stromal cells: 10.5;Exocrine glandular cells: 7.9;Glandular and luminal cells: 8.6;Hofbauer cells: 6.0;Pancreatic endocrine cells: 6.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.3;basal ganglia: 23.4;cerebral cortex: 33.2;hippocampal formation: 45.4;white matter: 16.4" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.79e-1)" "unprognostic (1.74e-3)" "unprognostic (1.63e-1)" "unprognostic (1.48e-2)" "unprognostic (4.90e-2)" "unprognostic (1.39e-2)" "unprognostic (5.21e-3)" "unprognostic (6.00e-2)" "unprognostic (2.12e-2)" "unprognostic (1.35e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.68e-2)" "unprognostic (2.93e-1)" "unprognostic (3.96e-3)" 11.9 10.1 18.3 5.9 23.4 0.4 9.1 3.4 33.2 15.3 19.7 27.8 9.2 22.4 8.1 6.7 13.5 9.0 58.4 45.4 2.2 8.4 8.1 6.5 5.1 1.0 2.9 20.8 8.3 6.0 7.4 4.1 4.7 15.2 8.7 13.2 5.9 24.8 49.5 8.5 11.4 15.7 0.0 5.8 16.7 7.6 6.3 2.0 5.3 27.5 5.0 21.6 11.5 16.4 4.1 12.3 19.5 8.4 3.2 0.6 7.4 14.1 7.1 2.7 0.0 2.6 0.4 19.5 2.4 14.0 4.6 1.6 11.6 0.0 0.1 0.3 9.8 0.0 0.0 13.1 4.1 0.1 2.0 1.8 0.9 0.2 0.0 0.0 0.1 0.2 0.2 2.7 3.2 16.5 0.1 9.5 7.7 16.3 0.4 10.6 20.2 3.5 2.5 18.1 7.0 2.4 8.4 11.4 13.6 13.7 16.4 0.6 0.1 8.8 13.8 5.2 3.7 21.3 23.4 0.4 16.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 18.3 23.4 3.4 33.2 45.4 2.2 1.0 2.9 4.7 0.0 6.3 16.4 8.5 0.0 8.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 4.2 4.2 0.0 0.0 2.5 1.8 0.0 0.3 0.9 0.0 0.0 7.1 0.0 5.7 10.5 1.9 0.0 0.0 0.0 7.9 0.7 2.9 0.0 8.6 1.3 3.9 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.4 0.0 0.0 2.0 1.5 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.3 0.8 1.2 0.0 0.0 ISX RAXLX ENSG00000175329 "Intestine specific homeobox" Q2M1V0 22 35066136-35087387 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 69 "intestine: 37.5" "Group enriched" "Detected in some" 32 "Distal enterocytes: 24.2;Enteroendocrine cells: 19.4;Intestinal goblet cells: 16.0;Paneth cells: 19.4;Proximal enterocytes: 32.7;Undifferentiated cells: 23.8" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "CACO-2: 1.6;Hep G2: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA060328 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies" "HPA060328: AB_2684254" "unprognostic (5.02e-2)" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "unprognostic (3.33e-1)" "unprognostic (3.86e-1)" "unprognostic (2.55e-1)" 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 37.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 26.0 0.0 0.0 0.0 0.0 0.0 27.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.2 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.1 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 23.8 0.0 HMGXB4 "HMG2L1, THC211630" ENSG00000100281 "HMG-box containing 4" Q9UGU5 22 35257452-35295807 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000725, HPA076681" Approved Approved Nucleoplasm NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA000725: AB_1079073, HPA076681: " "unprognostic (2.22e-1)" "unprognostic (1.12e-1)" "prognostic favorable (3.24e-5)" "unprognostic (4.81e-2)" "unprognostic (1.93e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (4.79e-4)" "unprognostic (2.85e-2)" "unprognostic (8.25e-3)" "unprognostic (6.67e-3)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.62e-1)" "unprognostic (8.71e-3)" "unprognostic (1.13e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" 7.9 4.7 5.1 7.8 6.5 23.4 8.1 6.5 7.2 6.7 3.7 6.6 6.4 11.6 3.7 8.6 7.6 7.0 6.5 5.3 5.8 4.1 5.1 5.6 7.5 5.9 5.3 14.0 7.0 8.2 2.2 9.0 5.8 7.4 7.4 8.5 6.7 6.2 7.2 6.7 6.7 9.5 4.9 6.3 5.0 7.9 6.1 11.3 6.7 7.2 7.7 8.6 5.3 8.2 22.6 4.9 37.6 17.6 9.3 16.4 9.9 22.3 31.6 22.1 20.1 4.3 8.9 27.5 10.2 23.3 13.4 13.0 14.9 18.3 26.2 23.3 18.6 24.6 6.5 5.3 11.2 56.8 25.1 15.8 14.0 18.5 14.2 13.3 16.8 21.0 19.7 21.6 17.1 11.0 35.1 15.1 15.7 15.6 14.2 25.3 32.5 10.7 13.8 17.5 22.1 23.0 19.6 15.6 16.5 10.6 9.6 16.1 13.3 20.1 41.9 24.1 19.5 26.1 25.5 34.8 17.1 15.9 31.7 34.5 12.5 16.9 13.4 14.8 11.7 10.4 13.1 14.3 9.8 13.3 8.4 9.6 19.0 9.6 13.8 10.8 12.1 5.9 5.1 6.5 6.5 7.2 5.3 5.8 5.9 5.3 5.8 4.9 6.1 8.2 30.6 12.8 18.5 18.3 30.9 20.9 52.3 33.3 16.5 60.6 26.0 25.1 14.4 34.3 29.7 27.6 35.5 48.0 30.1 31.5 29.4 40.4 14.7 22.2 35.5 32.4 16.9 56.6 17.7 29.3 54.5 34.8 27.5 31.9 52.1 51.9 36.8 24.1 31.8 67.3 20.5 31.9 28.5 26.4 17.6 12.7 53.7 29.1 8.8 7.5 32.1 21.0 34.0 17.1 31.5 35.3 27.4 56.8 21.2 58.1 26.4 21.0 15.6 73.5 39.5 46.4 32.9 67.0 82.9 28.0 22.6 64.7 30.4 33.1 32.3 57.8 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.8;Erythroid cells: 96.6;monocytes: 137.7;Syncytiotrophoblasts: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 44000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB000101: AB_2235163, HPA000845: AB_1079338, HPA052880: AB_2681979" "unprognostic (6.71e-2)" "prognostic favorable (2.81e-6)" "unprognostic (5.29e-3)" "unprognostic (7.94e-2)" "unprognostic (1.83e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.78e-4)" "prognostic unfavorable (3.95e-4)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (1.37e-1)" "unprognostic (8.07e-2)" "prognostic unfavorable (3.58e-5)" "unprognostic (3.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-3)" "unprognostic (1.53e-1)" 15.2 7.1 5.8 49.1 10.4 138.7 14.4 8.3 7.4 14.5 5.8 20.2 19.6 16.3 3.3 25.1 13.7 9.6 8.9 5.8 7.0 9.1 14.9 14.8 70.1 10.3 7.7 25.6 12.6 10.3 5.3 25.2 9.6 10.2 16.7 2.3 13.9 9.6 13.3 17.6 28.3 12.2 8.1 47.3 17.9 20.6 9.0 58.9 12.1 8.0 53.6 12.7 15.6 12.3 213.0 147.5 115.7 118.8 11.0 22.2 100.6 138.1 71.2 199.4 188.3 98.9 102.4 137.9 78.8 70.5 83.6 103.8 116.0 108.3 64.4 112.7 212.6 198.3 141.5 203.7 3.9 414.0 172.4 12.3 9.7 120.0 32.4 18.4 88.7 124.5 124.0 201.2 76.9 172.7 341.8 137.9 154.9 143.4 86.7 379.6 164.8 173.0 39.4 120.1 88.2 94.8 188.3 75.4 41.8 60.9 78.8 155.6 54.1 201.3 153.1 127.2 145.4 111.9 150.2 265.2 130.9 153.5 157.6 66.5 59.8 43.4 49.5 69.6 35.8 127.5 43.1 53.1 77.8 106.1 34.0 39.0 28.4 65.5 81.2 88.8 96.6 77.1 5.8 10.4 8.3 7.4 5.8 7.0 10.3 7.7 9.6 8.1 9.0 12.3 8.1 6.4 7.3 1.3 49.5 10.6 13.6 12.1 8.6 1.5 9.2 10.8 3.5 8.6 6.0 7.3 0.0 147.8 30.4 12.0 5.9 19.8 2.8 6.2 4.1 11.8 3.5 96.6 0.3 12.7 77.1 11.2 18.8 9.0 15.2 65.7 13.2 5.3 53.1 1.7 0.4 16.6 4.1 24.0 29.4 5.1 10.8 28.4 7.2 7.5 137.7 5.7 13.4 3.0 6.0 11.0 8.6 6.0 49.3 4.0 6.5 5.7 4.8 3.7 19.7 8.8 14.5 16.1 58.8 14.9 6.3 82.2 19.4 8.5 34.6 9.8 RASD2 "MGC:4834, Rhes, TEM2" ENSG00000100302 "RASD family member 2" Q96D21 22 35540831-35553999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 212.9" "Group enriched" "Detected in some" 4 "Intestinal goblet cells: 13.1;Sertoli cells: 46.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 212.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.1;hTERT-RPE1: 9.8;SK-BR-3: 5.6;U-2 OS: 3.1;U-87 MG: 4.0" "Region enriched" "Detected in all" 8 "basal ganglia: 589.6" "Region enriched" "Detected in all" 8 "basal ganglia: 429.3" HPA005839 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA005839: AB_1079745" "unprognostic (1.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.33e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (7.07e-3)" "unprognostic (9.76e-2)" "unprognostic (5.49e-2)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.00e-3)" "prognostic unfavorable (2.22e-5)" "unprognostic (3.75e-2)" "unprognostic (1.61e-1)" "unprognostic (8.42e-3)" "unprognostic (6.22e-2)" 1.8 7.3 30.8 2.5 212.9 3.8 2.3 0.0 30.7 3.1 0.0 28.2 2.3 4.7 15.0 1.9 5.6 2.2 8.6 12.5 9.9 1.5 0.4 3.2 0.4 4.6 12.5 1.2 1.6 1.2 2.1 0.2 6.4 15.2 4.0 0.5 4.0 22.7 15.0 1.6 6.2 7.3 1.8 0.2 3.8 0.7 48.4 0.7 1.2 4.5 1.2 4.3 2.5 9.0 0.1 2.2 0.0 0.4 0.0 0.0 0.0 0.5 0.2 0.8 0.6 0.1 0.4 0.0 0.1 1.9 3.1 0.1 0.1 0.0 0.7 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.1 2.5 1.6 0.2 9.8 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.0 1.5 0.2 1.6 5.6 0.0 0.1 0.4 0.1 0.0 1.3 3.1 0.1 0.7 1.4 0.5 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 212.9 0.0 30.7 12.5 9.9 4.6 12.5 6.4 1.8 48.4 9.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 1.7 2.9 3.3 1.9 0.0 0.2 0.0 0.0 0.0 0.7 3.0 0.0 0.2 0.1 0.1 0.2 2.9 0.0 0.0 3.2 0.2 0.0 3.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.6 13.1 2.0 0.0 0.8 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 1.0 0.7 0.0 2.3 0.7 0.0 0.5 0.1 0.0 0.1 0.2 46.0 0.4 6.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.5 0.3 MB PVALB ENSG00000198125 Myoglobin P02144 22 35606764-35637951 "Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Oxygen transport, Transport" "Muscle protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 13154.5;skeletal muscle: 40709.4;tongue: 29085.2" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 5182.1" "Group enriched" "Detected in many" 7 "breast cancer: 13.6;head and neck cancer: 31.1;prostate cancer: 30.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 6 "NK-cells: 1.3" "Cell line enriched" "Detected in some" 4 "SK-BR-3: 175.6" "Low region specificity" "Detected in many" "CAB000060, HPA003123" Enhanced NA NA 13500000 140000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "CAB000060: , HPA003123: AB_1079442" "unprognostic (7.51e-2)" "unprognostic (3.92e-3)" "unprognostic (1.07e-1)" "unprognostic (7.71e-2)" "unprognostic (2.35e-1)" "unprognostic (4.66e-3)" "unprognostic (5.78e-3)" "unprognostic (1.18e-1)" "unprognostic (2.74e-1)" "unprognostic (1.72e-1)" "unprognostic (2.74e-3)" "unprognostic (1.17e-2)" "unprognostic (8.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.35e-1)" "unprognostic (3.44e-3)" "unprognostic (1.19e-2)" 8.1 4.6 1.2 1.5 1.2 0.3 43.4 1.2 2.2 2.9 0.9 14.6 1.8 2.3 0.3 736.1 18.7 4.1 13154.5 1.0 1.9 2.8 5.8 14.9 5.3 1.4 1.4 5.3 26.9 16.1 10.6 3.1 1.2 214.2 12.9 0.2 367.1 0.5 40709.4 23.0 11.1 1.4 1.2 2.1 3.8 4.5 1.5 0.8 8.5 29085.2 1.8 1.3 4.5 1.0 1.9 7.6 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 4.6 0.7 0.1 0.3 1.0 0.8 0.2 0.0 0.0 5.4 0.3 0.1 0.5 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.5 0.5 0.0 19.2 0.1 0.6 0.0 1.9 2.3 0.9 0.5 8.0 0.0 6.4 1.5 0.2 19.0 175.6 0.0 0.3 39.4 0.1 0.4 0.5 1.2 2.2 0.2 0.0 0.0 0.2 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.2 1.0 1.9 1.4 1.4 1.2 1.2 1.5 1.0 0.3 0.0 0.0 0.3 0.1 0.3 4.3 12.5 0.0 0.0 30.7 23.9 5182.1 0.0 30.8 0.0 0.0 0.1 0.5 3.8 0.0 4.7 20.1 20.2 0.1 40.7 11.5 0.0 0.0 0.2 0.0 145.2 0.0 0.2 0.0 0.8 0.0 0.4 0.0 0.0 0.1 114.6 14.2 0.0 0.4 70.0 0.0 2.1 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.7 0.0 21.8 2.6 0.1 19.9 0.0 0.0 420.9 42.0 0.3 0.7 0.6 0.1 0.3 2.8 0.1 2.9 15.1 APOL6 "APOL-VI, APOLVI" ENSG00000221963 "Apolipoprotein L6" Q9BWW8 22 35648446-35668404 "Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 46.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 135.9;NK-cells: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB028574, HPA029165, HPA029167" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" Cytosol "CAB028574: , HPA029165: AB_10670037, HPA029167: AB_10670832" "unprognostic (7.25e-3)" "unprognostic (2.67e-2)" "unprognostic (1.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-1)" "unprognostic (1.55e-1)" "unprognostic (2.32e-2)" "unprognostic (8.29e-2)" "unprognostic (3.76e-2)" "unprognostic (6.26e-3)" "unprognostic (1.46e-3)" "unprognostic (1.46e-1)" "unprognostic (6.65e-3)" "unprognostic (2.49e-2)" "unprognostic (4.17e-2)" "unprognostic (1.71e-2)" "prognostic favorable (6.61e-4)" 23.4 7.3 4.1 15.8 4.3 16.1 10.0 3.4 4.0 6.8 3.3 13.2 19.2 5.5 5.5 5.9 6.6 9.1 4.2 3.9 5.1 6.4 46.5 15.5 15.5 8.7 5.0 12.2 2.9 2.6 2.4 7.8 5.8 7.9 11.8 2.6 14.0 5.1 3.1 4.5 19.7 7.4 6.7 18.2 14.0 2.3 4.9 10.1 8.5 3.9 10.4 13.2 3.7 5.4 12.8 4.1 0.3 1.5 30.1 15.0 17.3 5.3 14.2 17.3 21.7 2.0 14.2 17.7 2.6 14.0 12.6 16.2 0.1 8.6 4.5 33.6 0.1 7.4 2.6 4.0 23.7 10.4 12.4 19.3 5.7 5.9 3.3 3.9 3.6 8.0 0.8 31.2 3.2 1.3 14.6 3.2 0.5 0.9 5.3 6.1 6.8 8.7 7.6 28.9 0.4 0.2 8.5 7.2 10.0 1.1 1.2 12.1 3.9 4.3 2.6 3.0 2.8 16.4 14.2 1.7 8.1 16.2 6.1 7.5 4.8 2.6 7.3 7.6 6.1 1.0 4.8 5.8 2.4 0.7 4.6 5.3 7.5 5.0 8.5 0.3 5.5 4.2 4.1 4.3 3.4 4.0 3.9 5.1 8.7 5.0 5.8 6.7 4.9 5.4 58.6 70.5 34.3 6.8 15.7 8.0 10.8 14.7 13.6 0.2 16.8 10.8 7.3 34.3 38.6 12.9 0.0 8.3 79.1 101.1 9.8 33.6 10.5 18.4 48.9 33.4 47.3 11.6 0.2 41.9 35.6 33.4 41.8 17.2 36.8 12.2 39.3 135.9 34.9 0.0 1.3 55.3 20.3 58.1 19.9 7.4 26.1 50.5 8.8 17.8 68.5 3.8 126.7 9.5 2.1 45.7 43.7 18.8 51.0 43.2 88.6 31.6 47.4 0.0 0.0 25.3 22.0 0.5 0.2 15.6 5.3 2.5 67.7 6.0 35.9 62.0 APOL5 APOLV ENSG00000128313 "Apolipoprotein L5" Q9BWW9 22 35717872-35729483 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 1.4;tongue: 2.0" "Cell type enhanced" "Detected in single" "Early spermatids: 1.1" "Cancer enriched" "Detected in single" 7 "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 14 "U-698: 1.7" NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.23e-1)" "unprognostic (7.61e-4)" "unprognostic (9.34e-2)" "unprognostic (1.39e-2)" "unprognostic (3.23e-1)" "unprognostic (4.18e-2)" "unprognostic (4.37e-5)" "unprognostic (3.23e-2)" "unprognostic (2.78e-2)" "unprognostic (2.94e-2)" "unprognostic (1.59e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RBFOX2 "FOX-2, HNRBP2, HRNBP2, RBM9" ENSG00000100320 "RNA binding fox-1 homolog 2" O43251 22 35738736-36028824 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 378.7;Inhibitory neurons: 418.1;Oligodendrocyte precursor cells: 237.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006240, HPA006455, HPA075862" Approved Supported Nucleoplasm NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA006240: AB_1079750, HPA006455: , HPA075862: " "unprognostic (3.17e-1)" "unprognostic (4.80e-2)" "unprognostic (9.30e-2)" "unprognostic (3.21e-3)" "unprognostic (3.42e-1)" "unprognostic (2.74e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.63e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (5.78e-3)" "unprognostic (2.13e-2)" "unprognostic (1.53e-2)" "unprognostic (6.08e-2)" 28.4 21.9 16.4 12.3 21.7 0.2 27.0 38.8 41.9 49.0 0.0 59.2 11.7 67.5 21.6 34.7 40.4 25.2 37.0 24.3 11.7 18.7 25.8 25.6 5.9 6.9 3.3 63.0 18.7 26.2 27.5 32.6 5.2 31.4 21.4 15.5 23.7 29.7 77.1 23.7 23.4 52.7 1.1 9.9 28.9 25.7 7.3 10.0 28.5 44.3 8.5 43.1 36.5 17.8 46.2 27.4 110.3 64.8 62.4 111.2 36.8 89.9 123.6 67.1 72.0 60.1 21.3 28.2 41.2 108.9 41.9 46.5 40.2 41.7 95.9 19.2 36.6 16.7 26.5 22.3 18.8 4.4 11.6 77.3 53.1 59.6 73.3 64.8 86.8 7.0 13.7 3.9 80.3 14.0 4.5 2.7 40.5 19.7 42.0 7.6 92.0 7.9 50.1 47.5 34.1 106.0 110.3 15.5 31.0 57.0 16.9 6.8 105.5 96.4 54.4 54.7 41.2 2.8 9.4 38.3 42.7 6.8 51.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 16.4 21.7 38.8 41.9 24.3 11.7 6.9 3.3 5.2 1.1 7.3 17.8 34.3 67.3 38.5 189.4 1.0 37.1 50.6 57.3 57.5 20.8 31.4 34.5 62.2 31.5 40.4 27.6 0.0 69.9 0.9 17.9 35.2 53.0 24.8 17.8 60.8 45.9 57.0 0.8 378.7 32.1 89.1 67.8 15.8 25.0 2.5 30.6 40.7 26.0 10.5 117.8 418.1 24.7 18.3 1.3 14.7 9.4 79.6 1.8 16.0 183.6 2.6 16.9 0.0 237.2 130.0 77.4 10.7 93.3 1.4 57.4 22.5 18.7 20.9 6.7 52.6 74.5 93.3 42.2 25.6 31.0 33.8 29.0 2.5 48.2 23.8 61.1 APOL3 "APOLIII, CG12-1" ENSG00000128284 "Apolipoprotein L3" O95236 22 36140330-36166177 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 59.1;Endothelial cells: 69.8;Hepatic stellate cells: 69.7;Kupffer cells: 38.7;NK-cells: 46.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 34.1;ASC TERT1: 54.1;HDLM-2: 25.6;Karpas-707: 59.0" "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "prognostic favorable (6.82e-4)" "unprognostic (5.93e-3)" "unprognostic (6.79e-2)" "unprognostic (2.70e-2)" "unprognostic (2.22e-1)" "unprognostic (7.05e-2)" "unprognostic (6.30e-2)" "unprognostic (2.67e-1)" "unprognostic (8.94e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (7.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" 58.2 12.3 10.1 25.4 10.0 10.1 43.7 8.7 12.2 17.2 7.6 16.3 15.0 18.8 12.3 12.0 24.4 14.3 33.7 8.8 9.1 19.0 39.9 42.0 43.4 11.4 10.1 9.6 6.3 3.4 8.5 16.3 10.0 18.4 11.4 0.6 15.7 14.9 16.6 19.6 21.7 16.0 8.8 47.6 12.3 2.9 10.8 18.1 25.2 19.6 20.8 17.6 19.5 8.7 4.3 0.0 0.0 0.1 34.1 54.1 1.8 1.8 10.2 3.1 7.0 0.0 9.5 2.1 0.4 5.0 4.6 0.7 0.0 1.3 1.9 25.6 0.0 9.2 1.3 2.1 18.3 0.1 2.6 11.4 0.0 9.0 0.4 2.1 22.1 2.0 0.2 59.0 1.1 0.1 11.7 0.3 0.1 0.0 0.5 16.9 0.0 1.3 0.3 3.0 0.2 0.1 6.0 4.2 0.1 0.0 0.0 1.2 16.2 1.5 0.6 1.7 0.5 15.6 10.8 0.1 3.7 3.5 1.5 8.3 19.1 0.8 16.9 23.4 27.3 9.7 14.4 17.5 15.4 8.0 13.4 14.3 2.3 18.5 24.6 0.5 14.7 17.2 10.1 10.0 8.7 12.2 8.8 9.1 11.4 10.1 10.0 8.8 10.8 8.7 59.1 3.2 8.6 1.6 21.1 5.0 4.3 3.9 2.2 0.0 5.8 4.2 7.9 8.6 4.3 3.7 0.0 1.9 16.0 0.3 0.0 2.5 0.9 1.8 4.7 69.8 0.0 20.6 0.0 1.6 1.2 18.8 7.1 1.3 9.5 2.0 69.7 20.6 6.9 0.0 0.0 7.5 2.0 38.7 10.6 1.4 24.2 19.6 3.6 9.4 29.2 0.7 46.4 0.0 0.0 3.0 0.1 9.8 15.3 10.4 5.3 2.8 4.2 0.3 13.1 3.2 10.1 0.2 0.3 4.1 4.1 0.8 31.5 4.3 2.3 4.7 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 APOL2 APOL-II ENSG00000128335 "Apolipoprotein L2" Q9BQE5 22 36226209-36239954 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 80.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA001078, CAB026695" Supported NA NA 29000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "CAB026695: , HPA001078: AB_10602432" "unprognostic (4.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.50e-2)" "unprognostic (4.26e-3)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.38e-2)" "unprognostic (7.39e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.22e-7)" "unprognostic (1.80e-1)" "unprognostic (6.79e-2)" "unprognostic (2.66e-2)" "prognostic favorable (5.06e-6)" 42.0 23.4 36.5 43.6 38.3 13.0 37.4 37.0 49.7 36.8 34.9 28.8 41.8 33.1 17.8 18.4 30.2 42.1 40.0 38.6 43.2 52.6 65.4 44.8 42.5 52.0 41.6 19.5 15.3 19.7 47.3 22.3 52.3 34.2 26.5 12.2 25.0 28.3 28.0 16.2 32.3 35.8 42.1 46.6 38.3 6.8 38.2 29.6 19.4 18.3 30.4 59.5 26.1 38.2 24.0 18.7 17.0 12.7 63.6 49.1 31.7 32.1 73.4 84.1 113.3 7.1 19.2 29.3 52.4 57.2 52.0 11.1 18.3 25.4 41.6 98.0 21.3 13.4 39.9 33.5 107.3 29.0 25.2 62.4 17.0 59.2 15.5 35.2 55.8 16.4 24.8 79.1 53.2 9.4 29.8 13.2 6.3 8.6 16.4 30.3 21.6 17.3 85.6 63.3 30.2 8.5 21.8 40.7 18.4 11.5 12.8 4.1 54.8 50.6 25.1 10.6 17.9 47.6 25.8 9.1 43.7 15.0 19.6 31.1 22.8 16.8 39.7 46.6 36.3 16.3 28.6 33.2 16.5 10.3 16.2 27.1 116.5 28.4 34.0 10.2 29.2 14.3 36.5 38.3 37.0 49.7 38.6 43.2 52.0 41.6 52.3 42.1 38.2 38.2 14.8 35.3 16.8 8.5 12.5 6.0 8.0 21.4 0.6 5.0 7.5 5.0 24.3 21.5 20.1 12.9 0.0 16.6 17.1 31.8 17.6 42.6 0.2 53.0 21.1 21.2 4.8 8.6 18.1 62.9 10.7 19.5 21.4 80.2 2.5 8.3 18.9 65.4 24.2 6.7 9.3 12.0 22.4 20.9 13.0 1.9 16.8 15.0 8.8 7.5 26.6 9.3 25.7 12.1 4.8 68.1 14.5 20.7 17.9 28.4 33.1 25.6 15.6 5.1 0.0 23.9 12.4 0.4 0.2 2.8 6.7 15.2 19.1 10.4 8.0 19.4 APOL1 APOL ENSG00000100342 "Apolipoprotein L1" O14791 22 36253071-36267530 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 220.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 106.1;Glandular and luminal cells: 216.2;Hepatocytes: 115.6;Pancreatic endocrine cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 243.9;HDLM-2: 166.1;HHSteC: 120.3;RPTEC TERT1: 91.1;RT4: 146.8" "HPA018885, CAB056156" Supported "Secreted to blood" NA NA 1640000000 9200000000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "CAB056156: AB_2665576, HPA018885: AB_1844953" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (8.98e-3)" "unprognostic (1.67e-1)" "unprognostic (8.28e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (5.35e-4)" "unprognostic (4.41e-2)" "unprognostic (1.58e-1)" "unprognostic (4.07e-3)" "unprognostic (5.15e-2)" "prognostic unfavorable (7.43e-6)" "unprognostic (1.93e-1)" "unprognostic (3.15e-2)" "unprognostic (5.05e-3)" "prognostic favorable (2.01e-5)" 45.3 15.8 8.1 62.5 8.2 4.2 28.4 7.8 9.8 53.8 9.4 32.0 32.7 38.8 17.7 25.7 36.7 69.0 29.5 7.4 8.4 44.5 220.5 59.5 23.1 10.0 8.5 24.8 9.0 4.9 14.1 53.0 9.6 37.5 27.2 0.9 29.7 52.2 11.7 7.1 28.9 65.4 9.0 56.8 64.9 7.9 10.8 24.9 18.0 13.8 23.6 117.7 29.9 8.2 21.6 5.1 0.1 0.6 46.8 44.6 14.2 2.3 9.0 13.7 38.6 0.6 34.4 7.0 243.9 24.8 31.3 5.3 0.0 19.2 3.6 166.1 0.2 6.1 3.2 41.4 120.3 2.4 20.2 8.3 1.7 38.0 0.8 2.0 27.3 1.3 23.8 85.1 2.4 0.2 8.5 2.1 0.6 0.6 0.2 13.6 2.6 3.2 91.1 146.8 1.9 0.1 10.9 5.8 2.1 0.3 0.8 7.8 24.7 29.5 12.4 3.2 1.5 6.5 4.0 1.6 16.0 12.4 4.6 15.6 6.1 5.5 12.6 6.8 10.7 2.6 8.1 11.2 4.3 1.4 4.6 6.3 16.1 22.4 10.3 0.5 5.4 7.2 8.1 8.2 7.8 9.8 7.4 8.4 10.0 8.5 9.6 9.0 10.8 8.2 37.4 57.7 34.3 0.3 7.2 1.7 21.4 73.5 2.8 0.5 6.3 3.0 3.6 15.7 67.1 18.4 2.1 11.0 12.6 31.2 0.0 37.8 0.8 106.1 48.8 41.3 7.7 3.8 0.1 20.0 8.2 27.3 45.9 216.2 11.4 4.3 49.6 115.6 9.1 0.0 0.1 17.7 32.6 15.8 5.3 1.4 27.4 10.9 0.0 7.5 19.4 0.1 36.0 0.0 0.0 105.1 19.9 24.0 15.0 31.2 20.5 2.1 60.5 1.3 6.6 5.5 10.6 0.4 0.4 3.4 2.3 6.7 12.9 1.6 4.6 62.5 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 84000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB008681: AB_1623682, HPA000994: AB_1080267" "unprognostic (5.11e-2)" "unprognostic (4.40e-3)" "unprognostic (4.40e-3)" "unprognostic (1.07e-2)" "unprognostic (5.85e-2)" "unprognostic (4.28e-2)" "unprognostic (4.02e-2)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" "prognostic favorable (2.04e-4)" "prognostic favorable (1.17e-6)" "unprognostic (1.49e-2)" "unprognostic (2.78e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" 60.3 182.3 89.8 45.5 92.4 64.7 58.0 94.6 98.2 57.4 92.4 65.3 84.0 50.0 51.7 79.8 64.1 49.4 122.3 87.9 90.7 91.5 149.5 44.7 59.2 92.9 91.3 75.8 59.2 99.1 43.4 47.3 91.9 59.3 63.6 43.0 59.5 52.5 159.4 60.5 64.3 48.3 91.2 65.7 76.1 48.8 97.0 50.9 67.7 180.1 59.9 59.0 54.0 91.7 52.8 80.4 75.4 126.8 115.2 125.0 81.3 70.8 108.1 114.8 128.7 87.9 52.1 133.3 64.2 116.8 54.5 76.1 151.7 127.4 66.1 93.6 131.8 147.7 91.7 125.4 94.6 189.6 125.8 162.3 98.9 101.9 79.3 99.5 118.2 78.4 157.7 104.1 106.1 80.3 87.5 128.2 60.0 170.3 95.3 75.3 79.5 92.6 116.4 84.8 99.9 98.3 70.2 148.1 125.3 61.3 103.6 165.9 83.7 120.5 95.0 69.8 65.9 81.4 64.2 128.6 111.0 109.5 74.1 30.2 173.5 32.3 102.5 194.3 108.9 140.4 101.2 109.0 223.4 133.8 116.4 108.6 59.3 145.4 170.1 167.1 110.9 224.3 89.8 92.4 94.6 98.2 87.9 90.7 92.9 91.3 91.9 91.2 97.0 91.7 68.9 60.9 53.0 12.1 66.4 83.5 87.7 154.0 108.1 105.6 124.3 137.7 105.4 88.6 82.5 69.9 39.6 213.2 62.8 128.5 303.3 93.0 19.6 45.7 70.6 73.7 89.5 114.0 8.3 106.2 275.8 74.0 75.4 57.2 69.1 148.0 81.0 122.7 173.4 116.1 10.3 132.4 95.6 100.5 80.7 36.8 56.5 80.7 78.2 8.4 91.9 168.9 77.2 9.0 13.5 82.5 104.3 50.8 79.5 52.7 252.2 213.7 49.0 59.4 19.7 61.1 67.1 49.1 42.4 124.5 89.8 207.1 62.4 287.0 179.6 87.1 FOXRED2 "ERFAD, FLJ23322" ENSG00000100350 "FAD dependent oxidoreductase domain containing 2" Q8IWF2 22 36487190-36507043 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 5.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 5.4" "Cell line enhanced" "Detected in many" "SiHa: 147.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031611, HPA031612" Approved "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA031611: AB_10599975, HPA031612: AB_10601887" "unprognostic (3.66e-1)" "prognostic favorable (4.86e-5)" "unprognostic (6.73e-2)" "unprognostic (1.26e-1)" "unprognostic (4.66e-1)" "unprognostic (7.58e-2)" "unprognostic (2.24e-3)" "unprognostic (2.00e-2)" "unprognostic (4.31e-1)" "unprognostic (7.15e-3)" "unprognostic (1.67e-2)" "unprognostic (1.48e-2)" "unprognostic (2.15e-2)" "unprognostic (9.56e-3)" "unprognostic (4.49e-1)" "prognostic unfavorable (9.32e-4)" "unprognostic (9.42e-2)" 5.5 8.1 15.5 4.9 14.8 3.7 4.6 6.7 17.1 9.5 9.0 4.2 4.8 8.1 10.4 4.5 6.6 5.3 5.0 18.0 7.7 6.8 7.7 3.8 5.3 5.5 9.5 13.7 3.6 5.2 4.2 6.3 5.8 7.7 4.2 7.5 6.0 5.5 7.0 7.6 3.1 6.0 5.9 11.3 4.3 5.8 9.9 5.2 4.7 6.4 4.9 5.2 3.8 11.9 31.1 32.7 17.1 35.7 10.7 5.1 26.5 16.2 15.7 31.8 26.3 85.8 15.5 42.4 26.4 12.9 2.2 16.5 32.1 8.5 20.4 15.0 50.8 27.6 20.2 38.6 29.2 27.2 88.9 14.8 8.4 21.2 9.3 7.5 10.5 32.7 33.8 0.7 19.5 27.3 29.0 14.2 15.1 25.0 27.5 52.5 38.4 18.8 12.4 21.5 34.8 44.9 147.5 30.3 27.0 6.4 43.4 14.9 11.8 41.1 51.9 30.3 18.6 11.6 19.0 33.2 13.5 23.9 32.8 0.5 0.9 0.1 0.2 1.1 1.2 0.3 0.2 0.3 0.8 0.4 0.6 0.5 0.3 0.2 0.8 5.4 0.2 0.4 15.5 14.8 6.7 17.1 18.0 7.7 5.5 9.5 5.8 5.9 9.9 11.9 0.9 0.0 4.5 6.8 2.9 2.8 2.6 0.8 3.4 11.6 4.1 3.7 5.5 2.8 0.7 5.5 4.2 11.2 6.1 1.0 1.9 1.9 0.3 2.2 6.2 3.0 0.0 3.4 3.5 1.6 5.4 7.5 1.1 3.9 2.5 7.8 1.8 11.7 10.8 10.1 9.1 1.5 0.0 16.6 3.7 0.9 9.3 4.2 3.6 0.0 1.3 8.6 1.0 6.0 5.5 0.9 0.2 7.5 2.1 1.9 0.4 5.5 1.1 4.0 0.0 12.7 2.3 8.9 22.3 4.7 4.0 3.6 0.9 7.6 3.1 1.4 EIF3D "eIF3-p66, eIF3-zeta, EIF3S7" ENSG00000100353 "Eukaryotic translation initiation factor 3 subunit D" O15371 22 36510855-36529184 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045882, HPA063330, HPA066216" Approved Supported Cytosol NA NA 36000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA045882: AB_2679482, HPA063330: AB_2684988, HPA066216: AB_2685637" "unprognostic (4.98e-2)" "unprognostic (2.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.50e-3)" "unprognostic (1.39e-2)" "unprognostic (2.34e-3)" "prognostic unfavorable (8.10e-5)" "unprognostic (1.47e-1)" "unprognostic (2.58e-1)" "unprognostic (9.98e-2)" "unprognostic (5.54e-3)" "unprognostic (3.93e-2)" "unprognostic (5.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.72e-1)" "unprognostic (5.22e-2)" "unprognostic (9.78e-2)" 121.7 84.3 46.1 105.2 48.9 176.9 184.5 48.6 48.2 127.8 59.0 118.7 107.3 121.7 123.7 144.5 158.1 84.6 95.0 46.2 48.0 88.4 88.0 87.5 174.1 51.1 48.6 193.3 228.0 108.1 55.3 109.8 51.3 97.8 135.5 45.6 132.8 102.2 152.1 153.4 100.1 118.7 48.9 138.6 129.3 63.5 50.8 162.6 113.5 93.1 211.8 134.7 116.2 52.2 312.4 171.3 172.2 197.2 237.8 462.3 287.8 235.2 321.2 319.5 313.7 270.7 171.1 395.3 173.4 271.8 202.4 230.9 295.1 374.5 320.7 215.7 313.6 215.4 151.9 209.6 428.2 507.5 214.4 419.6 427.7 357.1 515.0 365.1 347.5 128.0 238.3 195.9 363.6 194.0 180.3 281.0 188.5 484.9 141.6 318.1 278.0 305.0 314.2 214.9 135.9 190.7 153.6 311.3 337.4 180.0 196.7 472.5 243.9 247.9 222.6 188.3 333.6 247.5 171.8 316.9 252.1 318.1 242.7 166.7 383.7 141.3 320.3 353.5 520.4 518.1 461.1 381.1 528.9 509.2 558.2 455.7 95.1 402.3 348.9 303.3 608.7 826.1 46.1 48.9 48.6 48.2 46.2 48.0 51.1 48.6 51.3 48.9 50.8 52.2 115.6 60.9 92.0 13.7 184.7 212.9 287.1 299.1 134.9 37.3 231.9 216.8 67.9 130.1 167.1 46.0 31.3 224.2 151.5 68.2 150.6 191.7 126.3 108.4 95.3 141.7 112.7 101.4 8.5 207.8 240.4 99.4 78.0 88.1 187.3 128.9 126.7 41.0 219.7 25.2 8.7 149.1 109.9 211.0 176.1 46.4 138.5 121.7 129.9 8.4 275.1 75.6 137.0 10.6 12.5 185.6 134.7 108.3 72.5 230.6 176.5 160.1 119.9 46.2 72.3 147.9 260.8 106.0 83.2 140.3 215.8 246.1 159.8 162.2 219.7 288.0 CACNG2 "MGC138502, MGC138504, stargazin" ENSG00000166862 "Calcium voltage-gated channel auxiliary subunit gamma 2" Q9Y698 22 36560857-36703752 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 20.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 87.5;Horizontal cells: 26.9;Inhibitory neurons: 119.7;Oligodendrocyte precursor cells: 43.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (7.54e-2)" "unprognostic (3.06e-1)" "unprognostic (8.80e-3)" "unprognostic (2.34e-2)" "unprognostic (3.07e-2)" 0.0 0.7 5.7 0.0 7.1 0.0 0.0 13.8 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 6.0 0.0 0.0 0.0 0.0 5.9 3.8 0.0 0.0 0.0 1.2 0.0 6.5 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 7.1 13.8 20.7 6.0 6.0 5.9 3.8 6.5 2.6 6.2 11.0 0.0 0.0 0.0 3.9 0.0 0.0 0.2 0.0 0.0 8.4 0.0 0.0 0.4 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 87.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 119.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.0 0.2 0.0 43.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 IFT27 "BBS19, FAP156, RABL4, RAYL" ENSG00000100360 "Intraflagellar transport 27" Q9BW83 22 36758202-36776256 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 257.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 4 "U-138 MG: 159.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048791 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 17: WM-115 - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "HPA048791: " "unprognostic (3.04e-2)" "unprognostic (7.25e-3)" "unprognostic (7.06e-2)" "prognostic favorable (1.91e-4)" "unprognostic (9.04e-2)" "unprognostic (6.05e-2)" "unprognostic (6.22e-2)" "unprognostic (1.98e-1)" "unprognostic (2.16e-1)" "unprognostic (7.75e-3)" "unprognostic (4.85e-3)" "unprognostic (2.10e-1)" "unprognostic (9.62e-3)" "unprognostic (8.08e-2)" "unprognostic (1.41e-1)" "unprognostic (1.95e-1)" "prognostic favorable (5.55e-4)" 11.6 21.7 24.5 8.5 25.5 8.8 11.5 25.7 27.0 13.5 32.3 19.3 12.3 13.8 19.4 9.7 36.6 9.5 23.9 23.9 24.6 22.3 18.4 11.2 9.8 24.9 28.9 15.1 16.2 23.2 39.6 8.0 26.4 15.2 9.7 15.6 14.6 16.5 15.0 11.6 12.5 8.8 25.8 11.8 16.1 23.2 25.5 9.7 18.1 11.9 9.1 14.9 11.1 25.9 17.8 21.9 25.3 28.8 19.9 19.1 15.1 14.1 18.2 18.3 16.1 0.9 15.9 19.3 24.2 13.2 26.3 16.1 13.9 16.0 14.1 37.1 37.4 5.1 4.3 0.0 36.6 6.2 23.3 15.5 25.6 19.4 8.9 14.8 19.6 15.7 9.1 15.5 12.5 32.6 7.7 5.5 13.5 34.4 28.5 36.4 0.0 10.8 18.3 11.4 24.3 26.4 15.0 11.4 37.8 21.3 25.8 11.0 11.6 159.2 9.3 21.3 2.7 36.2 23.6 7.0 25.1 15.5 35.3 14.5 31.8 36.1 24.6 25.0 24.6 22.8 20.4 23.0 39.2 26.0 19.9 19.0 11.7 23.1 30.0 30.5 29.9 21.1 24.5 25.5 25.7 27.0 23.9 24.6 24.9 28.9 26.4 25.8 25.5 25.9 23.6 6.4 18.4 34.3 18.8 23.3 29.0 50.1 12.5 35.2 29.9 32.1 19.9 20.0 51.6 40.5 29.2 27.2 15.2 19.9 105.7 26.1 66.0 110.5 20.2 23.2 53.3 7.8 8.9 23.0 20.9 27.8 14.3 18.7 33.0 27.6 26.0 18.7 40.7 30.3 12.3 46.9 65.1 13.8 25.0 24.3 27.4 17.8 35.6 5.6 13.2 60.5 21.6 11.6 10.4 19.8 18.3 31.6 29.5 24.7 39.4 57.0 257.2 41.9 13.1 24.2 26.9 78.5 17.9 14.1 33.2 17.5 19.0 21.0 31.6 27.9 PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "parathyroid gland: 2129.3" "Group enriched" "Detected in some" 7 "Distal tubular cells: 641.8;Horizontal cells: 1527.7" "Cancer enriched" "Detected in many" 4 "renal cancer: 59.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Cell line enriched" "Detected in some" 291 "RPMI-8226: 1561.0" "Region enriched" "Detected in all" 5 "cerebellum: 2120.1" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: AB_563948, HPA048536: AB_2680433" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "unprognostic (9.75e-2)" "unprognostic (1.79e-3)" "unprognostic (7.80e-2)" "unprognostic (2.49e-2)" "unprognostic (2.52e-2)" "unprognostic (6.53e-2)" "unprognostic (2.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (1.91e-1)" "unprognostic (1.65e-2)" "unprognostic (8.99e-3)" 0.4 1.0 82.5 0.7 40.2 0.1 15.0 255.6 86.5 0.1 8.6 0.3 0.2 1.4 0.8 0.1 0.1 0.3 0.2 9.3 100.5 82.1 5.7 2.2 2.4 127.4 85.7 0.5 0.2 2129.3 1.2 2.4 105.7 0.3 0.3 373.5 2.7 0.7 13.6 0.1 0.3 0.5 50.9 3.2 0.8 1.5 275.5 0.3 5.0 0.4 3.1 3.8 0.2 51.8 0.0 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.1 0.4 1561.0 0.0 5.3 2.3 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 4.6 0.0 0.0 0.9 0.3 15.1 82.5 40.2 255.6 86.5 9.3 100.5 127.4 85.7 105.7 50.9 275.5 51.8 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 0.0 51.3 2.4 2.0 0.6 0.0 0.0 38.6 10.4 0.3 0.0 0.0 641.8 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 11.4 0.2 30.0 0.2 53.8 1527.7 29.7 0.0 0.0 2.9 0.0 0.1 0.6 15.7 0.0 2.8 0.1 37.4 0.0 3.0 3.3 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 150.5 0.0 1.0 0.0 0.0 3.6 0.0 0.0 0.4 0.9 0.0 0.0 0.1 NCF4 "p40phox, SH3PXD4" ENSG00000100365 "Neutrophil cytosolic factor 4" Q15080 22 36860988-36878017 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.2;lymphoid tissue: 162.3" "Cell type enhanced" "Detected in many" "B-cells: 70.9;granulocytes: 74.1;Hofbauer cells: 198.4;Kupffer cells: 85.3;Langerhans cells: 55.8;Macrophages: 85.7;Plasma cells: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 657.3;eosinophil: 750.1;neutrophil: 1235.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 1235.8" "Cell line enhanced" "Detected in some" "HEL: 78.3;HMC-1: 396.0;NB-4: 148.7;REH: 76.5;RPMI-8226: 144.0;THP-1: 137.9;U-937: 76.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010146, HPA036156, HPA057975" Enhanced Enhanced Cytosol NA NA 7800 "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" Cytosol "CAB010146: AB_627989, HPA036156: AB_2674974, HPA057975: AB_2683568" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (2.68e-2)" "unprognostic (1.36e-3)" "unprognostic (1.35e-1)" "unprognostic (2.78e-3)" "unprognostic (4.20e-2)" "unprognostic (3.69e-2)" "unprognostic (4.03e-2)" "unprognostic (2.70e-1)" "unprognostic (3.27e-2)" "unprognostic (2.54e-1)" "prognostic unfavorable (7.06e-8)" "unprognostic (3.60e-1)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" 29.5 14.4 4.8 43.1 5.0 180.2 12.7 4.9 7.5 4.6 6.4 19.2 11.7 4.5 1.0 7.2 13.9 13.0 9.4 4.9 5.4 8.9 10.1 45.1 39.8 6.8 5.9 3.3 4.1 1.4 5.3 24.3 6.4 7.4 11.8 0.1 10.7 4.5 3.6 4.9 42.6 10.5 5.8 162.3 9.3 1.8 8.6 12.9 8.1 7.1 33.5 18.7 7.2 7.1 1.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 28.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 78.3 0.0 0.0 0.0 12.8 396.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 26.8 0.0 0.8 0.0 148.7 0.0 0.0 0.0 76.5 0.0 144.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 137.9 0.0 0.0 0.2 0.1 0.2 0.5 0.1 23.7 0.1 76.8 0.1 657.3 184.6 750.1 2.3 92.5 9.8 108.2 32.0 6.9 86.1 85.9 1.9 2.1 1235.8 4.4 62.0 100.7 96.3 106.3 4.8 5.0 4.9 7.5 4.9 5.4 6.8 5.9 6.4 5.8 8.6 7.1 1.5 3.2 18.7 0.0 70.9 2.8 2.2 1.3 0.6 0.0 3.1 2.5 2.1 0.0 5.8 1.8 0.0 3.2 21.1 1.3 0.0 0.6 0.2 0.2 0.1 3.6 0.0 28.8 0.0 3.1 16.0 1.8 2.0 0.4 74.1 0.0 1.4 0.7 198.4 0.0 0.0 0.5 2.0 85.3 55.8 1.0 0.6 85.7 14.2 3.7 38.5 0.0 3.1 0.0 0.1 0.9 22.5 0.0 68.2 0.3 0.2 0.2 0.9 0.3 0.0 0.5 1.6 0.0 0.4 0.5 2.3 13.0 17.5 0.7 1.7 4.3 CSF2RB "betaGMR, CD131, IL3RB, IL5RB" ENSG00000100368 "Colony stimulating factor 2 receptor subunit beta" P32927 22 36913628-36940439 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.5;lymphoid tissue: 65.5" "Cell type enhanced" "Detected in many" "dendritic cells: 44.8;Extravillous trophoblasts: 37.9;granulocytes: 91.2;Langerhans cells: 68.3;Late spermatids: 41.2;Macrophages: 34.7;monocytes: 42.3;Plasma cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "basophil: 238.1;neutrophil: 76.0" "Lineage enriched" "Detected in many" 16 "granulocytes: 238.1" "Group enriched" "Detected in some" 5 "HEL: 107.3;HMC-1: 321.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078677 Approved "Golgi apparatus" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus" "HPA078677: AB_2732389" "unprognostic (1.67e-2)" "unprognostic (9.44e-3)" "unprognostic (1.03e-2)" "unprognostic (6.66e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.47e-5)" "unprognostic (1.86e-1)" "unprognostic (1.94e-2)" "unprognostic (4.38e-1)" "unprognostic (9.57e-2)" "unprognostic (1.33e-1)" "unprognostic (3.21e-1)" "unprognostic (1.82e-3)" "unprognostic (5.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.95e-1)" "unprognostic (8.52e-2)" 10.1 2.0 1.0 65.5 1.1 54.5 5.4 1.2 5.2 2.5 1.3 9.9 10.3 2.0 0.7 6.6 2.6 9.8 2.3 0.9 1.6 1.8 2.6 15.1 40.1 2.6 2.1 0.5 2.1 0.9 0.7 31.3 3.1 1.6 8.5 0.0 4.9 1.5 1.0 5.4 11.0 7.0 2.3 22.8 9.3 2.1 3.0 9.8 2.7 4.0 62.5 18.3 2.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.0 0.0 0.0 0.0 26.8 0.1 0.0 0.0 0.3 0.0 0.0 0.1 16.1 0.0 107.3 0.0 0.0 0.1 1.7 321.1 0.0 0.0 0.0 0.0 0.0 18.5 0.0 0.1 12.6 0.0 0.0 0.1 11.2 0.0 0.0 0.0 10.7 0.0 40.0 0.0 0.0 0.1 0.0 0.0 2.5 0.0 0.1 0.1 9.6 0.3 1.0 0.1 0.3 0.0 1.6 1.1 6.8 0.2 15.6 0.1 238.1 9.1 23.5 0.0 7.7 0.0 1.6 0.2 0.0 4.8 1.1 0.0 0.0 76.0 0.0 7.0 14.4 2.3 10.3 1.0 1.1 1.2 5.2 0.9 1.6 2.6 2.1 3.1 2.3 3.0 2.9 4.3 0.0 9.1 1.6 9.1 7.1 0.0 0.0 0.0 0.0 0.2 0.3 1.2 2.8 1.8 0.0 0.0 3.4 44.8 0.0 0.0 0.0 13.4 0.0 0.2 22.0 0.0 32.0 0.1 0.2 37.9 2.8 0.0 0.0 91.2 0.0 4.6 0.0 20.1 0.0 0.1 0.0 0.0 31.9 68.3 41.2 0.0 34.7 12.4 5.6 42.3 0.0 2.1 0.0 0.0 0.0 0.0 0.4 49.5 0.1 0.0 0.1 2.9 0.0 0.0 0.3 0.5 0.0 0.0 0.1 6.3 16.6 2.9 0.1 0.0 0.2 TEX33 "C22orf33, EAN57, MGC35206" ENSG00000185264 "Testis expressed 33" O43247 22 36991120-37007851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 442 "testis: 91.4" "Group enriched" "Detected in some" 43 "Early spermatids: 873.2;Late spermatids: 258.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA005998 Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA005998: AB_1078352" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 873.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 258.2 4.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 12.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TST RDS ENSG00000128311 "Thiosulfate sulfurtransferase" Q16762 22 37010859-37020183 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 561.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 565.8;Hepatocytes: 414.9;Paneth cells: 463.4;Proximal enterocytes: 278.5;Proximal tubular cells: 254.5;Undifferentiated cells: 217.4" "Cancer enhanced" "Detected in all" "liver cancer: 177.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 25.0" "Group enriched" "Detected in all" 6 "dendritic cells: 25.0;granulocytes: 21.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "OE19: 264.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003044, HPA003643, CAB009546" Enhanced Supported Mitochondria NA NA 560000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "CAB009546: AB_2211220, HPA003044: AB_1858417, HPA003643: AB_1080411" "unprognostic (3.09e-2)" "unprognostic (2.70e-1)" "unprognostic (2.07e-1)" "unprognostic (1.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.11e-1)" "unprognostic (2.49e-2)" "unprognostic (2.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.96e-3)" "unprognostic (4.38e-2)" "unprognostic (1.78e-1)" "prognostic favorable (7.59e-6)" "unprognostic (6.08e-3)" "unprognostic (3.46e-1)" "unprognostic (1.16e-1)" "prognostic favorable (1.04e-4)" 51.4 154.1 31.3 20.9 40.5 27.1 37.3 38.2 36.0 34.1 31.3 190.7 147.7 18.9 2.9 96.7 25.7 75.9 69.9 29.1 33.1 100.8 561.2 22.7 8.1 34.4 35.2 26.9 63.6 9.4 12.4 7.9 34.4 26.4 80.3 1.3 39.8 18.2 52.9 33.8 114.2 13.2 35.4 16.9 88.4 8.1 35.8 4.3 17.1 34.9 16.2 30.0 56.7 39.0 42.6 86.1 10.8 36.8 25.9 10.6 21.4 23.0 18.6 12.6 18.3 25.4 25.7 11.1 18.8 17.0 11.9 35.1 7.9 22.3 2.7 33.6 50.0 11.5 15.5 49.7 64.9 16.4 26.4 20.1 23.9 9.1 7.6 17.5 31.1 5.9 14.2 18.2 6.0 90.8 0.5 49.9 18.7 264.4 39.3 37.0 11.7 19.7 35.9 36.7 6.4 17.1 24.2 41.4 31.7 10.2 43.4 39.3 25.1 14.0 27.2 24.2 7.4 14.0 15.4 3.4 5.3 46.4 8.5 10.9 17.7 8.0 0.8 4.7 1.7 2.8 0.8 0.6 25.0 1.7 0.4 0.2 21.8 3.7 1.5 1.7 2.1 8.1 31.3 40.5 38.2 36.0 29.1 33.1 34.4 35.2 34.4 35.4 35.8 39.0 13.9 28.9 74.8 10.1 7.8 1.3 9.5 20.4 12.0 1.3 32.7 16.6 39.2 170.1 23.7 20.2 0.0 11.6 2.5 565.8 46.9 45.3 1.9 53.3 30.2 13.4 34.3 35.3 0.3 44.0 6.4 14.6 126.9 74.3 14.0 60.9 39.3 414.9 15.1 1.7 0.5 162.8 8.2 28.9 6.8 3.5 13.1 23.2 1.8 1.0 18.6 27.3 3.1 3.5 7.4 36.8 463.4 7.9 24.5 10.5 278.5 254.5 19.2 0.8 0.0 10.7 11.5 2.4 0.5 39.8 2.4 11.4 5.0 57.5 217.4 17.3 MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 390.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 553.6;Hepatocytes: 578.6;Paneth cells: 621.4;Proximal enterocytes: 1322.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 2900000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Mitochondria Cytosol "HPA001240: AB_1079408" "unprognostic (7.18e-3)" "unprognostic (4.45e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-3)" "unprognostic (1.73e-3)" "unprognostic (1.43e-1)" "unprognostic (7.07e-2)" "unprognostic (2.15e-1)" "unprognostic (2.22e-1)" "unprognostic (1.35e-1)" "unprognostic (2.25e-1)" "unprognostic (1.58e-1)" "unprognostic (3.15e-3)" "unprognostic (3.98e-2)" "unprognostic (3.51e-1)" "unprognostic (2.52e-1)" "prognostic favorable (5.89e-4)" 58.0 57.3 25.3 10.0 32.3 36.5 51.0 29.0 31.0 40.9 29.8 102.4 106.5 34.7 0.6 91.5 42.9 16.6 64.2 22.9 23.4 71.4 390.7 43.5 8.8 34.0 27.5 81.7 106.4 4.8 14.7 9.1 29.7 45.3 17.0 0.5 43.5 9.6 89.7 82.3 93.0 7.0 26.0 22.1 70.3 51.7 31.4 4.5 24.8 23.1 6.0 48.3 62.3 35.1 44.0 50.4 24.2 50.0 27.8 17.2 38.1 23.4 20.6 24.8 33.2 48.6 18.9 68.7 33.0 16.7 16.7 29.9 20.9 33.8 3.6 41.4 119.2 26.5 21.3 115.6 87.5 29.0 35.6 30.0 64.2 16.1 15.1 22.8 50.6 33.1 48.0 19.3 7.0 33.8 2.6 97.5 45.7 56.7 52.2 73.6 28.8 51.9 25.5 14.0 12.4 92.9 15.6 23.9 46.6 12.2 26.0 45.6 39.8 21.3 60.1 23.9 16.0 33.3 16.8 21.0 7.7 34.7 11.1 48.5 71.9 54.7 31.0 27.5 42.4 24.9 20.1 26.4 104.0 25.0 2.7 10.4 21.9 87.8 12.7 16.3 44.3 35.4 25.3 32.3 29.0 31.0 22.9 23.4 34.0 27.5 29.7 26.0 31.4 35.1 21.3 35.3 61.9 14.7 25.1 81.6 80.4 120.3 70.6 4.5 81.4 83.4 29.4 243.1 70.0 60.7 0.0 61.9 20.3 553.6 133.1 146.4 191.1 38.5 46.8 42.6 108.6 122.6 1.1 148.3 119.1 52.8 87.1 72.5 17.2 140.3 108.5 578.6 77.5 3.3 1.9 363.1 85.5 84.6 77.6 115.1 91.0 62.7 58.7 3.7 60.7 24.8 56.7 4.5 14.9 117.9 621.4 84.7 65.7 77.7 1322.1 469.8 13.4 2.8 46.0 34.4 36.0 101.3 11.5 133.7 152.9 50.1 26.6 57.7 397.5 110.6 KCTD17 FLJ12242 ENSG00000100379 "Potassium channel tetramerization domain containing 17" Q8N5Z5 22 37051736-37063390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Ubl conjugation pathway" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 90.8" HPA018459 Uncertain NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA018459: AB_1852169" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (1.09e-1)" "unprognostic (1.61e-2)" "unprognostic (5.38e-2)" "unprognostic (3.09e-3)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.89e-1)" "unprognostic (4.90e-2)" "unprognostic (2.19e-1)" "prognostic favorable (4.22e-5)" "unprognostic (8.62e-2)" "prognostic unfavorable (5.13e-12)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.32e-1)" "unprognostic (6.94e-2)" 8.2 15.6 64.8 9.8 113.7 2.4 6.7 46.0 71.6 14.2 44.4 15.9 3.4 14.9 1.8 7.2 10.7 8.5 26.6 68.0 54.1 5.8 3.5 9.3 10.6 44.8 70.4 13.7 3.7 7.8 43.0 6.5 52.4 11.2 5.2 3.6 3.4 9.0 1.7 21.1 10.4 9.4 43.8 11.1 7.9 46.0 83.8 7.0 7.6 3.0 6.9 16.9 13.0 55.5 15.9 20.5 31.7 23.7 14.9 14.8 1.2 16.2 15.6 25.9 22.3 4.4 4.6 12.2 10.9 20.8 20.3 4.2 10.0 19.0 10.9 23.8 26.8 5.2 5.6 4.9 22.1 0.0 6.1 17.3 9.2 26.6 5.8 17.5 33.6 15.9 1.2 13.2 16.5 12.8 11.0 0.3 20.3 9.4 17.4 19.8 8.4 3.6 6.7 4.1 26.4 32.9 15.0 14.1 7.5 6.6 3.8 4.2 19.6 33.5 31.2 16.0 12.0 17.7 5.5 2.0 29.6 7.3 18.6 0.0 0.8 0.0 0.9 1.0 0.9 1.2 0.6 0.9 0.9 0.4 0.8 0.6 0.0 1.6 0.4 0.2 1.0 0.4 64.8 113.7 46.0 71.6 68.0 54.1 44.8 70.4 52.4 43.8 83.8 55.5 8.8 0.0 0.5 11.1 5.8 1.5 4.6 2.8 1.2 17.3 1.3 1.5 5.0 4.3 0.8 5.5 2.1 0.4 5.0 17.7 0.0 11.9 24.9 0.7 12.7 9.7 13.1 0.8 22.4 6.1 2.8 9.9 4.1 0.9 4.5 12.0 12.8 0.5 9.2 13.5 11.6 5.3 0.0 9.6 17.0 28.1 10.5 9.8 3.6 1.9 13.0 16.4 8.2 4.5 7.1 3.2 16.0 9.1 4.6 1.2 0.5 2.5 1.5 7.8 0.0 7.8 11.7 19.7 7.1 1.3 4.8 7.5 8.5 10.2 7.0 2.4 TMPRSS6 "FLJ30744, MT2" ENSG00000187045 "Transmembrane serine protease 6" Q8IU80 22 37065436-37109713 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "liver: 128.4" "Group enriched" "Detected in some" 11 "Early spermatids: 61.0;Hepatocytes: 99.9;Late spermatids: 143.9" "Group enriched" "Detected in many" 14 "liver cancer: 51.3;thyroid cancer: 14.1" "Group enriched" "Detected in some" 4 "basal ganglia: 4.4;thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Hep G2: 5.0;SCLC-21H: 8.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 3.3" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (3.93e-1)" "unprognostic (3.28e-1)" "unprognostic (8.62e-2)" "unprognostic (6.29e-5)" "unprognostic (7.95e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.16e-6)" "unprognostic (2.44e-1)" "unprognostic (3.07e-1)" "unprognostic (2.41e-1)" "unprognostic (1.16e-2)" "unprognostic (3.58e-2)" "unprognostic (1.15e-7)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (2.39e-2)" "unprognostic (3.86e-5)" 0.1 0.1 0.2 0.2 4.4 0.2 0.4 0.1 0.6 0.1 0.0 0.6 2.2 0.1 0.8 0.2 0.5 0.9 0.0 0.2 0.2 0.1 128.4 0.7 0.3 0.2 0.4 0.1 1.3 0.0 13.0 0.7 0.2 0.2 0.5 0.1 0.0 0.0 0.0 2.2 1.0 0.0 0.0 0.2 3.6 7.7 1.3 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.6 0.1 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 0.2 0.1 5.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.0 0.0 8.1 0.3 0.1 0.6 0.0 0.1 0.1 0.0 0.4 0.3 1.0 0.1 0.0 1.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 0.1 0.6 0.2 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.6 0.3 0.5 2.8 0.0 0.0 0.0 0.0 0.1 8.8 0.0 0.2 61.0 0.0 0.0 0.3 5.3 8.0 0.1 0.0 2.6 0.0 2.6 0.0 0.0 0.0 2.5 99.9 0.1 0.0 0.1 1.5 0.0 3.2 0.0 143.9 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.1 0.3 0.3 0.1 0.6 0.0 IL2RB "CD122, IL15RB" ENSG00000100385 "Interleukin 2 receptor subunit beta" P14784 22 37125843-37175054 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.8;lymphoid tissue: 50.2;placenta: 36.3" "Cell type enhanced" "Detected in many" "dendritic cells: 130.1;Extravillous trophoblasts: 85.5;NK-cells: 388.3;T-cells: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "gdT-cell: 50.8;NK-cell: 186.4" "Group enriched" "Detected in many" 22 "NK-cells: 186.4;T-cells: 50.8" "Cell line enriched" "Detected in some" 8 "HDLM-2: 525.8" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Low region specificity" "Detected in some" HPA062657 Enhanced NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA062657: AB_2684822" "unprognostic (3.38e-3)" "unprognostic (1.21e-2)" "prognostic favorable (6.76e-4)" "prognostic favorable (3.18e-5)" "unprognostic (2.44e-2)" "unprognostic (9.69e-3)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (1.03e-3)" "unprognostic (5.37e-2)" "unprognostic (1.09e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (3.50e-7)" "unprognostic (4.63e-2)" "unprognostic (7.96e-2)" "unprognostic (3.94e-3)" "unprognostic (2.46e-2)" 3.2 1.3 2.0 22.4 1.6 36.8 1.9 0.8 2.3 2.2 1.5 5.1 5.5 7.6 2.9 3.5 2.9 6.8 1.9 2.2 1.0 1.0 8.5 12.4 35.7 2.4 2.2 1.6 0.8 0.4 0.6 36.3 1.9 2.3 5.2 0.0 4.3 3.2 0.7 8.9 8.3 2.5 1.7 50.2 6.4 1.5 3.3 14.9 1.8 0.7 24.0 8.0 1.0 1.8 0.4 0.0 1.0 0.0 0.0 0.0 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.0 525.8 0.6 1.0 0.0 0.1 0.0 0.0 24.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 1.3 0.0 0.7 0.1 4.2 3.3 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.2 0.6 2.3 0.0 0.9 0.0 0.0 13.2 0.0 0.6 36.2 66.0 0.1 0.4 0.4 0.5 5.4 0.1 0.5 50.8 0.6 27.4 0.4 11.4 28.6 0.1 1.9 3.6 15.0 1.2 186.4 0.5 0.3 24.4 37.3 2.0 1.6 0.8 2.3 2.2 1.0 2.4 2.2 1.9 1.7 3.3 1.8 1.5 3.2 6.8 0.0 3.6 3.2 0.7 0.1 5.7 0.0 1.0 0.8 1.7 0.0 0.6 1.8 0.0 0.6 130.1 0.2 0.0 0.3 2.2 0.5 1.2 1.0 0.0 16.8 0.1 0.2 85.5 1.4 5.6 1.2 10.1 0.1 7.1 1.8 2.3 0.0 0.1 0.1 0.0 5.3 1.7 1.6 0.3 3.7 5.4 0.0 2.0 0.0 388.3 0.0 0.1 0.0 0.0 0.0 18.6 0.2 0.1 0.2 0.7 0.0 0.0 0.2 0.9 0.0 0.3 0.5 1.6 1.2 103.6 0.0 0.3 0.1 C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 31.7;placenta: 29.6" "Cell type enriched" "Detected in many" 11 "Extravillous trophoblasts: 398.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 114.2;RT4: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" No No 354000000 "Cluster 48: NK-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "HPA002042: AB_1078342" "unprognostic (9.65e-2)" "unprognostic (1.21e-2)" "unprognostic (2.32e-1)" "unprognostic (2.23e-3)" "unprognostic (1.25e-3)" "unprognostic (3.01e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (9.60e-6)" "unprognostic (6.96e-2)" "unprognostic (5.11e-2)" "unprognostic (2.61e-2)" "unprognostic (1.72e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.61e-2)" "unprognostic (5.36e-2)" "unprognostic (1.08e-3)" "unprognostic (1.52e-2)" 4.9 6.7 4.4 6.6 4.5 1.6 4.0 4.3 5.3 11.1 4.3 5.5 1.6 31.7 1.4 2.7 7.0 8.8 3.7 4.5 4.3 7.4 13.0 5.2 5.1 5.1 4.5 5.5 3.5 2.2 2.5 29.6 4.8 6.8 3.6 0.5 3.2 2.9 1.5 5.0 5.4 8.2 4.4 6.5 3.5 6.2 4.8 2.4 3.8 0.7 2.3 5.6 4.3 6.3 17.7 20.5 10.7 3.6 1.8 21.3 32.6 3.4 6.8 2.8 2.0 3.8 24.7 0.1 14.1 6.0 1.5 34.9 0.4 8.4 1.2 4.9 2.6 2.8 8.3 3.8 7.1 0.1 2.3 29.2 4.9 2.3 0.6 7.3 25.5 0.8 0.1 7.7 1.1 114.2 0.0 0.5 7.1 2.5 0.3 0.2 0.1 2.8 24.5 50.7 1.8 14.6 1.0 19.7 2.8 5.5 7.0 0.5 9.4 1.1 5.6 0.4 0.1 15.5 0.4 0.1 2.1 2.0 3.2 0.4 0.1 0.5 0.2 0.2 0.2 0.2 0.4 0.3 0.1 0.7 0.9 0.7 0.5 1.5 0.1 0.3 1.4 0.3 4.4 4.5 4.3 5.3 4.5 4.3 5.1 4.5 4.8 4.4 4.8 6.3 3.2 0.0 0.0 13.7 2.9 1.5 2.1 1.9 0.6 1.0 8.6 4.2 1.8 1.5 2.2 1.8 0.0 8.1 1.5 7.9 1.9 3.4 2.0 4.8 30.8 6.8 0.0 0.8 3.3 1.1 398.9 7.6 2.0 9.6 1.3 19.8 10.0 7.2 9.3 0.0 4.3 3.1 0.0 1.9 1.4 8.9 0.6 1.2 5.4 3.7 1.1 4.5 1.0 4.0 7.8 2.7 2.8 0.4 3.4 0.8 2.0 1.6 2.7 0.9 0.0 2.2 7.5 7.2 4.5 1.0 0.3 34.5 3.1 7.6 4.4 1.5 SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.6;lymphoid tissue: 11.1;testis: 7.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.3;Late spermatids: 2.0;Microglial cells: 1.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Group enriched" "Detected in some" 11 "RPMI-8226: 23.3;SCLC-21H: 8.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" 0.1 0.3 2.2 1.0 2.2 0.4 0.0 1.2 6.4 0.0 0.0 0.2 1.3 1.1 0.0 0.0 0.1 0.0 0.0 1.9 2.2 0.1 0.0 0.0 1.8 6.8 3.5 3.3 1.8 0.0 2.6 0.0 6.7 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.5 1.0 1.2 0.6 0.2 7.8 7.6 11.1 0.0 0.0 0.9 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 8.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.1 0.9 0.0 0.0 0.0 0.0 0.1 0.2 2.2 2.2 1.2 6.4 1.9 2.2 6.8 3.5 6.7 1.2 7.6 2.3 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.4 0.0 0.0 RAC2 EN-7 ENSG00000128340 "Rac family small GTPase 2" P15153 22 37225270-37244448 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 411.9;lymphoid tissue: 387.9" "Cell type enhanced" "Detected in many" "B-cells: 329.0;dendritic cells: 381.4;granulocytes: 520.5;NK-cells: 717.9;Plasma cells: 287.8;T-cells: 419.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 522.5;HL-60: 734.5;HMC-1: 1427.9;Karpas-707: 684.5;U-87 MG: 618.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022946, HPA047820" Enhanced NA Yes 3300000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB022946: , HPA047820: AB_2680167" "prognostic favorable (1.03e-5)" "unprognostic (2.91e-1)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (6.74e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-1)" "unprognostic (5.00e-2)" "unprognostic (8.52e-3)" "unprognostic (2.65e-1)" "unprognostic (7.65e-2)" "unprognostic (3.81e-1)" "prognostic unfavorable (1.06e-6)" "unprognostic (1.45e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.50e-2)" 24.7 8.4 3.6 207.2 3.8 411.9 11.4 3.9 8.0 12.2 4.4 34.8 35.3 10.1 4.7 15.9 11.7 37.1 6.5 3.8 4.7 10.9 19.3 63.4 387.9 6.5 5.3 5.5 5.3 2.1 3.4 12.4 7.1 10.9 33.9 0.4 21.5 8.3 4.9 7.6 96.9 19.6 5.2 299.9 42.7 3.5 6.1 323.9 9.5 7.2 309.1 54.0 9.9 7.2 136.6 0.2 0.0 0.0 14.3 130.5 0.6 17.9 41.1 14.2 28.8 0.3 44.8 167.4 19.8 52.9 0.8 33.3 1.0 231.6 15.6 522.5 0.6 209.6 3.6 0.6 35.8 734.5 1427.9 96.4 32.3 25.1 84.3 0.9 239.7 159.1 50.5 684.5 1.9 0.2 218.9 291.2 2.8 13.1 87.2 72.3 0.7 193.8 22.6 0.1 2.0 0.6 0.9 23.0 2.7 0.8 9.7 391.8 258.7 0.6 23.5 1.0 2.0 307.0 171.4 176.6 618.6 316.5 35.1 1319.9 519.8 1602.2 972.1 695.5 731.5 761.7 768.6 858.9 494.0 672.8 584.3 759.8 1336.4 972.2 879.5 728.7 1163.4 1566.2 3.6 3.8 3.9 8.0 3.8 4.7 6.5 5.3 7.1 5.2 6.1 7.2 4.4 16.0 47.7 0.0 329.0 5.4 2.2 26.0 16.5 0.0 8.6 9.5 1.1 2.8 12.6 1.8 0.0 0.8 381.4 3.4 0.0 13.6 0.2 1.1 0.8 5.6 4.2 109.7 0.4 2.2 1.5 9.2 33.6 1.0 520.5 0.3 13.6 3.4 150.8 0.0 0.1 6.3 0.0 129.9 63.9 0.9 0.3 147.9 30.2 3.7 125.9 0.0 717.9 0.5 0.0 18.2 18.1 0.0 287.8 0.5 0.6 1.5 4.4 0.0 13.1 2.4 4.5 0.0 1.0 5.1 4.0 2.9 419.6 3.7 11.2 3.6 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.2;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 45.5;Excitatory neurons: 11.6;Inhibitory neurons: 16.2;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 18.2;basal ganglia: 13.8;cerebral cortex: 17.5;hippocampal formation: 16.6;white matter: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 12.0;CAPAN-2: 11.2;GAMG: 12.3;RPMI-8226: 11.7;RPTEC TERT1: 21.5;U-2 OS: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000781: AB_1079280" "unprognostic (2.74e-1)" "unprognostic (6.81e-2)" "unprognostic (2.80e-2)" "unprognostic (1.31e-5)" "unprognostic (3.28e-1)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "unprognostic (4.25e-2)" "unprognostic (6.05e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (4.51e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" 0.0 0.6 18.2 0.0 13.8 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 16.6 0.9 0.2 0.2 0.6 0.0 2.7 2.7 0.0 0.2 0.0 0.0 0.0 1.9 0.6 0.0 6.1 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.1 1.7 2.2 2.2 0.0 0.0 0.0 0.0 0.0 4.8 12.0 4.9 0.0 0.0 0.0 0.9 0.0 5.3 2.8 1.2 0.1 1.9 11.2 0.2 6.8 3.8 12.3 8.2 0.6 1.1 0.1 0.2 0.1 0.0 5.7 0.0 0.2 0.0 0.1 0.9 0.1 0.4 1.6 4.5 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.0 0.3 7.1 10.6 0.1 0.1 11.7 21.5 0.1 1.0 0.0 4.9 6.2 0.0 0.1 0.0 0.1 0.5 0.0 24.1 0.2 3.5 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 13.8 0.0 17.5 16.6 0.9 2.7 2.7 1.9 2.8 2.2 4.8 0.1 0.0 5.1 1.3 0.5 0.1 0.0 0.9 0.0 45.5 0.0 0.0 0.0 1.5 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.2 0.0 0.0 11.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.3 16.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 1.9 0.0 0.9 0.0 36.7 0.9 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.6 2.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1" "Cell type enhanced" "Detected in many" "Adipocytes: 51.4;dendritic cells: 54.6;Endothelial cells: 37.1;Hepatic stellate cells: 53.2;Kupffer cells: 45.8;monocytes: 40.6;NK-cells: 72.1;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 174.6;HEL: 143.4;HL-60: 220.9;HMC-1: 266.9;HUVEC TERT2: 232.9;TIME: 134.7;U-698: 166.8;U-937: 201.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 22.2 7.1 8.9 37.0 8.9 40.3 14.8 8.4 10.8 8.9 6.4 10.5 8.6 9.7 2.4 7.5 11.0 14.5 14.6 7.9 9.2 9.5 7.1 26.3 69.1 18.1 10.8 3.1 3.9 2.6 3.1 30.3 20.5 6.6 7.8 0.7 5.4 5.7 7.5 5.0 24.0 11.5 10.2 58.9 8.6 2.9 11.0 50.5 9.6 8.8 42.5 13.9 6.2 10.3 6.0 2.2 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 7.1 3.0 174.6 0.7 0.0 0.8 10.8 45.1 8.7 0.2 81.6 1.0 143.4 0.6 1.5 0.6 220.9 266.9 0.0 2.6 1.7 3.2 0.9 232.9 69.0 0.7 73.8 0.0 1.5 27.8 3.0 0.4 6.1 1.0 67.0 1.8 128.7 0.4 0.1 94.1 0.9 0.5 0.3 0.3 0.8 1.3 14.1 134.7 0.0 5.8 22.8 0.6 0.4 0.4 166.8 1.1 201.1 2.7 210.3 198.9 386.5 196.1 196.1 214.5 103.0 222.7 206.1 204.1 113.5 243.4 209.9 127.9 217.1 218.7 51.7 284.3 314.0 8.9 8.9 8.4 10.8 7.9 9.2 18.1 10.8 20.5 10.2 11.0 10.3 51.4 0.0 3.8 0.0 35.4 3.7 0.4 0.2 0.0 6.3 1.0 1.3 1.6 5.7 3.1 0.0 0.0 0.3 54.6 1.1 0.0 2.9 0.2 0.4 0.2 37.1 1.2 30.1 0.1 0.9 0.3 1.1 2.0 1.0 31.6 0.1 53.2 1.5 31.9 0.0 0.1 2.1 0.0 45.8 20.2 0.3 0.0 33.5 3.6 6.5 40.6 0.1 72.1 0.0 0.0 3.7 4.0 0.0 35.0 0.5 2.3 0.3 0.1 0.6 0.0 1.6 1.0 0.1 0.7 0.3 2.4 0.7 51.0 0.1 0.8 0.4 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 335.5;intestine: 198.0;kidney: 153.0;pancreas: 211.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 779.2;Distal enterocytes: 695.4;Langerhans cells: 982.8;Proximal enterocytes: 2724.7;Proximal tubular cells: 1764.8;Undifferentiated cells: 749.3" "Cancer enhanced" "Detected in all" "renal cancer: 54.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 27 "classical monocyte: 1464.7;intermediate monocyte: 553.8;myeloid DC: 1207.2" "Group enriched" "Detected in all" 50 "dendritic cells: 1207.2;monocytes: 1464.7" "Group enriched" "Detected in many" 4 "CACO-2: 109.4;Hep G2: 62.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria Nucleoplasm "CAB025198: , HPA003536: AB_1078936" "unprognostic (1.37e-3)" "unprognostic (4.11e-3)" "unprognostic (1.32e-3)" "unprognostic (4.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.91e-3)" "unprognostic (3.19e-1)" "unprognostic (9.92e-2)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (6.15e-2)" "unprognostic (5.19e-1)" "unprognostic (2.33e-3)" "unprognostic (1.80e-1)" "unprognostic (6.70e-2)" "unprognostic (5.01e-3)" "unprognostic (1.21e-1)" 7.5 1.4 0.6 23.5 1.4 19.2 5.4 0.2 1.1 1.8 0.2 55.0 41.2 3.6 1.0 5.2 4.4 335.5 1.6 0.5 1.0 153.0 5.0 8.6 60.7 1.6 1.2 0.9 211.5 0.2 0.1 1.7 1.4 2.2 81.1 0.1 2.1 0.7 1.9 9.9 198.0 5.2 0.4 59.2 10.7 0.6 1.1 41.3 1.0 0.7 64.0 8.2 0.5 3.4 2.8 1.5 0.9 1.0 0.0 0.0 1.1 1.7 0.0 0.0 0.0 109.4 0.1 0.4 0.3 0.0 0.3 1.7 0.0 0.0 0.0 0.2 1.1 0.0 0.0 62.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 2.8 0.0 1.0 0.4 21.2 0.3 0.0 0.9 1.3 0.0 0.0 0.0 0.3 1.7 1.9 2.4 0.5 1.6 1.7 6.4 2.0 1.0 4.3 0.8 0.0 0.2 0.3 2.7 0.2 1.3 7.7 1464.7 8.7 1.8 553.8 3.3 9.9 1.8 2.1 1207.2 2.3 2.3 1.9 26.8 2.3 39.7 9.6 3.0 981.5 0.6 1.4 0.2 1.1 0.5 1.0 1.6 1.2 1.4 0.4 1.1 3.4 1.6 6.4 3.9 0.0 16.4 17.1 0.1 0.5 0.0 0.0 13.2 7.5 0.3 779.2 1.4 29.5 0.0 0.2 7.0 695.4 127.2 26.3 0.1 0.1 0.3 2.3 73.7 4.8 0.1 206.7 0.3 3.2 5.6 0.2 2.5 0.0 0.7 1.9 26.4 0.0 0.1 413.0 0.0 100.8 982.8 0.3 0.6 150.8 24.9 0.0 164.8 0.0 4.1 0.0 0.1 291.6 331.6 0.0 0.9 0.3 2724.7 1764.8 2.1 0.0 0.0 0.3 2.3 0.0 0.4 0.1 12.4 0.3 8.6 0.0 749.3 0.3 GGA1 ENSG00000100083 "Golgi associated, gamma adaptin ear containing, ARF binding protein 1" Q9UJY5 22 37608725-37633564 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 179.3" "Cell type enhanced" "Detected in all" "Late spermatids: 221.2;Spermatocytes: 193.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048280, HPA051016" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA048280: AB_2680338, HPA051016: AB_2681312" "unprognostic (1.64e-1)" "unprognostic (1.42e-2)" "unprognostic (4.08e-1)" "unprognostic (9.23e-3)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.53e-2)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.16e-3)" 25.0 49.3 35.9 23.3 39.7 37.2 27.3 39.0 42.3 38.0 41.0 35.0 24.3 32.1 21.5 41.1 37.4 20.4 29.5 35.3 35.0 42.4 42.1 33.7 29.1 41.1 37.6 46.3 34.5 33.2 52.7 19.1 38.4 40.0 17.8 22.8 34.9 19.6 43.1 35.7 40.7 16.9 36.1 55.6 34.9 179.3 41.2 26.9 44.7 24.6 21.1 31.6 33.5 45.0 37.4 28.3 32.9 31.1 28.0 23.0 35.4 30.8 25.0 27.0 29.6 23.3 21.8 59.9 20.6 22.9 17.0 35.0 29.4 35.6 24.8 51.0 53.6 24.0 52.3 27.3 28.1 56.1 42.6 28.4 31.3 38.9 24.2 45.1 26.5 30.3 48.0 36.8 27.8 37.7 24.8 64.2 26.2 39.2 28.7 28.5 25.8 25.2 28.8 31.0 30.4 54.0 18.7 39.0 48.9 31.3 42.4 42.0 31.0 36.8 35.2 32.1 24.4 81.1 35.3 62.5 39.9 33.6 30.8 8.1 10.7 6.1 18.0 10.2 22.1 8.3 7.2 23.3 6.7 5.0 5.1 16.5 4.5 11.6 7.9 5.8 8.0 11.5 35.9 39.7 39.0 42.3 35.3 35.0 41.1 37.6 38.4 36.1 41.2 45.0 17.9 25.6 38.5 26.8 50.9 24.2 31.1 36.5 21.1 57.6 26.5 20.8 19.2 20.0 34.5 44.1 83.4 38.8 34.7 67.3 5.9 34.9 148.2 27.6 19.8 32.6 32.4 38.3 18.4 20.1 37.4 18.8 44.4 26.5 49.4 33.3 40.7 20.4 77.1 25.2 19.3 40.4 32.6 66.9 40.3 221.2 26.4 50.5 16.0 20.6 47.9 37.0 73.2 16.6 28.7 36.6 51.6 22.6 24.4 24.7 55.4 13.2 46.7 74.1 26.3 26.9 22.1 193.4 50.4 19.7 28.6 56.8 59.6 44.4 42.8 33.6 SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.5;HMC-1: 45.4;NB-4: 44.7" "Low region specificity" "Detected in all" HPA000757 Supported Approved Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA000757: AB_1079951" "unprognostic (7.81e-3)" "unprognostic (7.91e-3)" "unprognostic (3.42e-1)" "unprognostic (2.62e-2)" "unprognostic (5.38e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.55e-4)" "unprognostic (1.39e-1)" "unprognostic (3.08e-1)" "unprognostic (1.89e-1)" "unprognostic (2.59e-2)" "unprognostic (4.78e-1)" "prognostic unfavorable (3.48e-7)" "prognostic favorable (3.39e-4)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (8.48e-3)" 4.2 3.6 3.4 14.2 3.4 14.4 3.4 3.7 6.2 12.2 2.7 19.4 18.1 3.2 0.7 37.7 4.0 2.1 2.0 4.1 4.5 3.2 2.6 8.8 12.1 6.0 3.9 3.4 2.8 2.2 2.1 5.1 4.7 7.6 4.5 0.2 9.3 2.0 0.7 27.0 20.9 2.0 4.8 27.0 4.3 5.7 4.7 8.2 2.5 0.5 7.7 10.5 21.1 5.7 20.1 1.0 3.9 3.4 0.9 3.9 28.6 3.8 6.4 6.3 7.0 5.9 2.3 12.6 2.7 2.4 2.0 43.5 2.0 26.0 2.6 36.9 13.7 18.5 0.6 8.6 3.3 25.9 45.4 4.9 6.3 7.9 0.9 5.2 1.0 6.3 6.4 4.8 0.6 12.7 3.0 44.7 7.6 13.7 3.8 15.7 3.2 11.0 0.8 22.2 3.8 10.1 1.0 5.3 17.9 3.9 6.7 22.1 1.3 2.3 10.8 0.5 0.2 29.9 10.2 9.0 3.2 26.4 13.0 1.8 1.4 4.6 1.0 1.8 1.0 0.3 1.1 1.1 0.7 0.1 0.6 1.4 0.9 0.8 3.7 1.2 1.1 0.6 3.4 3.4 3.7 6.2 4.1 4.5 6.0 3.9 4.7 4.8 4.7 5.7 1.2 0.0 7.2 0.7 23.7 19.1 22.2 42.5 23.3 0.3 3.3 4.1 1.2 4.3 8.0 0.0 2.1 47.5 36.1 55.0 0.0 3.0 0.4 0.6 4.3 1.7 4.2 7.8 5.6 4.7 43.9 6.0 11.2 1.3 14.0 3.4 4.2 0.5 48.3 8.4 0.8 29.9 12.2 33.3 19.0 0.1 5.0 45.6 5.4 2.8 36.0 3.0 53.5 5.0 0.9 2.0 46.8 1.9 20.9 29.6 41.9 0.3 11.4 0.5 0.0 0.9 3.6 3.4 6.0 23.6 15.3 37.5 52.7 5.0 23.6 42.0 Z83844.2 ENSG00000285304 "Novel protein" 22 37639693-37666932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HL-60: 33.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000757 Approved Approved Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 3: HMC-1 - Innate immune response" Cytosol "HPA000757: AB_1079951" 1.0 0.2 0.1 7.3 0.0 8.8 1.0 0.1 1.4 3.1 0.0 5.9 5.6 1.3 0.0 4.0 1.6 1.3 0.5 0.2 0.1 0.0 0.9 3.4 7.4 0.0 0.0 1.0 0.7 2.6 3.7 0.2 0.9 5.0 0.1 2.1 2.3 0.2 1.7 8.1 2.3 0.1 3.9 1.4 0.7 0.2 6.5 0.5 0.0 6.6 4.2 0.4 14.7 2.1 7.7 5.0 2.3 6.5 8.3 4.1 12.9 15.3 15.8 9.8 3.5 8.4 1.4 4.5 5.1 12.2 9.2 22.3 4.7 10.2 7.0 21.3 0.0 10.7 4.2 33.2 25.5 7.8 9.4 17.7 1.6 6.5 0.9 6.1 5.9 7.5 0.7 13.4 1.2 1.9 7.9 23.9 1.6 12.6 4.9 7.7 1.6 4.5 4.4 7.2 1.1 4.9 8.0 5.4 6.4 14.5 1.5 2.0 7.5 1.2 0.0 12.3 4.7 8.8 5.2 21.5 14.8 0.0 0.6 0.0 0.4 0.3 0.3 0.3 0.2 0.5 0.9 0.2 0.6 0.4 0.0 0.5 0.6 0.4 0.6 0.3 0.1 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PDXP "CIN, dJ37E16.5, FLJ32703" ENSG00000241360 "Pyridoxal phosphatase" Q96GD0 22 37658723-37666932 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 209.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 19.4;Inhibitory neurons: 25.0;Microglial cells: 7.5;Oligodendrocyte precursor cells: 8.0;Oligodendrocytes: 5.8;Plasma cells: 9.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "plasmacytoid DC: 11.6" "Lineage enriched" "Detected in many" 8 "dendritic cells: 11.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000531 Approved NA NA 94000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA000531: AB_2666018" "unprognostic (6.29e-2)" "unprognostic (7.89e-3)" "unprognostic (1.00e-1)" "unprognostic (2.89e-1)" "unprognostic (2.15e-2)" "unprognostic (3.25e-2)" "unprognostic (2.81e-1)" "unprognostic (4.44e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-3)" "unprognostic (2.76e-2)" "unprognostic (1.77e-1)" "unprognostic (3.03e-3)" "unprognostic (2.04e-1)" "unprognostic (4.66e-2)" "unprognostic (2.38e-1)" 5.8 23.7 144.7 0.8 158.7 5.8 5.3 106.1 209.2 6.7 83.0 20.6 26.5 8.5 5.6 3.8 8.0 3.9 26.3 165.0 129.2 15.9 74.5 5.7 7.5 117.5 130.0 8.5 13.5 9.5 39.6 1.1 119.8 7.3 11.6 29.6 12.0 6.0 15.8 3.4 32.2 7.2 109.2 14.3 11.9 27.0 137.8 13.5 5.9 14.1 9.5 7.8 3.8 148.0 8.6 19.6 39.4 34.4 12.0 3.7 5.3 18.9 9.7 34.0 26.7 9.9 1.2 54.0 18.8 9.8 28.5 4.4 52.8 0.6 28.5 16.9 105.2 11.0 26.6 41.2 8.3 39.2 47.0 1.8 4.7 17.6 23.7 14.0 15.6 61.1 33.3 31.1 29.9 12.3 74.3 61.3 20.6 15.2 46.4 58.5 28.5 39.7 14.6 1.1 89.5 57.8 17.8 15.4 36.1 17.2 5.0 31.8 9.8 28.7 36.6 30.2 37.6 33.0 44.1 57.4 27.2 14.3 38.5 0.0 0.3 0.5 0.9 0.5 0.1 1.3 0.4 0.5 0.6 1.2 0.3 0.1 0.3 0.9 0.4 11.6 0.5 0.2 144.7 158.7 106.1 209.2 165.0 129.2 117.5 130.0 119.8 109.2 137.8 148.0 0.1 0.0 0.6 3.3 2.8 0.0 0.0 0.0 2.8 1.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.2 0.4 0.1 0.0 2.1 19.4 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 25.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 7.5 0.1 0.2 0.0 8.0 5.8 0.1 0.1 0.0 9.7 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.9 0.2 0.4 0.1 LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3949.7;Langerhans cells: 4906.5;monocytes: 7118.4;Smooth muscle cells: 4703.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 1649.6" "HPA000646, HPA000687, HPA001130, CAB002157" Enhanced Approved Nucleoplasm,Cytosol "Secreted to blood" No Yes 10000000 20000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol Nucleoplasm "CAB002157: AB_563734, HPA000646: AB_1078935, HPA000687: AB_2756309, HPA001130: AB_2756311" "unprognostic (1.65e-1)" "unprognostic (8.13e-2)" "unprognostic (5.13e-2)" "prognostic favorable (2.36e-5)" "unprognostic (6.38e-2)" "unprognostic (2.67e-3)" "prognostic unfavorable (3.06e-4)" "unprognostic (3.22e-3)" "unprognostic (4.91e-3)" "unprognostic (2.51e-1)" "unprognostic (6.16e-3)" "unprognostic (8.06e-2)" "prognostic unfavorable (1.18e-10)" "unprognostic (2.24e-2)" "unprognostic (8.13e-2)" "unprognostic (9.47e-2)" "prognostic unfavorable (5.10e-4)" 1921.2 778.5 482.4 523.8 520.7 324.7 1490.9 613.5 695.3 1805.7 465.2 1634.7 197.7 2270.1 196.8 387.4 1147.0 556.0 1397.4 457.7 549.0 362.4 277.4 920.2 176.7 694.5 576.1 1440.2 155.5 188.1 254.8 426.1 661.5 903.0 207.2 39.5 397.5 756.3 1172.9 472.8 475.3 1353.4 593.8 460.7 582.7 244.9 624.9 153.9 290.9 691.9 116.9 1059.7 1156.4 782.4 2850.9 1664.3 36.5 1440.9 3314.6 6505.1 32.7 6450.7 7619.4 4761.9 4716.9 189.6 368.3 3.3 649.1 6661.4 1609.2 296.3 58.8 4309.2 1663.3 2917.2 30.9 251.3 1606.3 791.1 2155.3 145.1 3167.7 4031.7 294.2 3785.7 1609.9 4271.1 5325.7 1.7 186.6 1163.4 3771.1 1287.6 5.2 2038.4 14.3 629.6 3914.9 5.4 2388.6 799.7 2000.0 6.4 5.5 843.4 1287.4 224.3 1644.5 66.7 1187.2 1689.0 7122.0 6224.0 3070.2 2788.9 3349.3 701.8 530.6 13.6 7291.9 762.0 2535.9 1086.5 3047.4 110.2 766.5 2320.4 113.6 567.7 694.9 754.2 3653.1 287.5 114.3 478.1 122.2 415.4 2556.7 899.2 1514.7 4667.0 482.4 520.7 613.5 695.3 457.7 549.0 694.5 576.1 661.5 593.8 624.9 782.4 1505.8 166.7 90.4 12.7 294.3 730.3 144.0 2796.6 49.5 10.0 144.2 477.9 986.3 74.4 213.4 163.7 6.2 88.0 466.5 49.9 17.6 690.2 30.9 183.0 3011.6 1063.6 3.0 74.9 7.5 90.4 1573.3 2540.4 28.1 230.3 540.0 172.2 653.2 614.1 3949.7 8.4 5.4 8.4 339.7 2159.0 4906.5 106.4 975.5 1700.0 2856.6 15.9 7118.4 278.0 588.1 4.0 17.1 233.5 6.1 1300.7 590.9 118.8 0.5 28.7 109.8 45.4 1650.1 1873.6 4703.8 33.8 13.1 18.2 588.0 151.5 767.5 197.2 11.6 57.0 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 TRIOBP "DFNB28, HRIHFB2122, KIAA1662, TAP68, Tara" ENSG00000100106 "TRIO and F-actin binding protein" Q9H2D6 22 37697048-37776556 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003747, HPA019769" Enhanced NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "HPA003747: AB_1858328, HPA019769: AB_1858329" "unprognostic (2.94e-1)" "prognostic favorable (4.29e-4)" "unprognostic (2.79e-1)" "unprognostic (4.57e-2)" "unprognostic (8.22e-2)" "unprognostic (7.44e-3)" "unprognostic (3.77e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "unprognostic (5.56e-2)" "unprognostic (2.40e-1)" "unprognostic (1.99e-1)" "unprognostic (4.38e-3)" "unprognostic (1.31e-1)" "unprognostic (2.81e-1)" "unprognostic (3.20e-2)" "unprognostic (1.67e-2)" 56.3 46.5 15.4 27.3 16.6 25.7 50.8 14.7 14.9 73.1 22.1 70.6 23.9 71.8 12.8 78.5 66.1 27.8 74.6 12.8 13.2 37.2 21.6 51.6 17.4 20.0 17.2 55.7 32.7 31.1 16.9 44.2 16.5 45.3 17.0 4.8 44.3 33.3 24.3 32.0 38.0 31.0 16.6 53.1 53.6 26.1 16.9 16.7 48.2 14.3 12.5 66.5 65.7 17.3 65.9 53.1 33.2 26.4 73.1 118.1 47.5 113.0 111.9 57.7 42.1 11.8 44.8 24.5 30.4 69.6 31.6 52.7 9.2 63.7 18.1 39.6 29.1 6.8 41.6 22.4 75.5 32.1 28.9 47.1 29.8 52.0 24.5 125.3 71.9 20.6 6.4 34.6 45.5 39.3 14.4 23.1 20.2 65.4 63.2 25.1 23.9 17.2 41.0 52.8 16.2 25.4 50.9 46.5 59.7 32.8 25.4 23.0 151.9 87.2 38.6 60.6 27.0 30.4 9.1 15.4 82.7 13.0 104.3 7.7 7.6 12.2 1.8 7.5 0.6 1.3 1.5 1.8 4.1 2.4 1.2 1.8 18.2 1.9 12.5 1.9 2.5 2.0 15.4 16.6 14.7 14.9 12.8 13.2 20.0 17.2 16.5 16.6 16.9 17.3 102.0 19.2 29.7 17.9 10.7 6.2 48.3 18.3 18.8 22.8 40.1 45.1 65.2 62.9 23.3 58.8 2.1 105.7 14.7 63.8 15.6 42.7 30.3 32.6 107.0 91.6 22.9 28.2 4.7 51.6 34.2 65.5 58.1 34.2 6.3 128.1 124.6 17.1 42.7 16.8 4.6 52.1 6.1 56.0 7.5 10.6 113.1 31.2 14.2 27.2 32.0 29.6 8.2 7.5 14.0 62.8 46.9 92.2 9.5 41.9 24.8 15.8 23.9 7.3 52.6 17.7 31.8 49.8 23.4 57.2 6.1 116.0 12.7 22.5 40.6 57.9 H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805093-37807436 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 660.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 51.4;Cytotrophoblasts: 42.9;Extravillous trophoblasts: 125.7;Hofbauer cells: 73.2;Syncytiotrophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.1;granulocytes: 17.1;monocytes: 11.7" "Cell line enhanced" "Detected in many" "OE19: 662.8;U-2 OS: 823.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: AB_1079062" "unprognostic (1.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-2)" "unprognostic (1.27e-1)" "unprognostic (3.31e-3)" "unprognostic (1.19e-1)" "unprognostic (2.18e-1)" "unprognostic (3.85e-1)" "unprognostic (7.68e-2)" "unprognostic (1.86e-1)" "unprognostic (5.95e-3)" "unprognostic (4.86e-3)" "prognostic favorable (7.68e-7)" "unprognostic (3.40e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-3)" "unprognostic (1.73e-1)" 89.8 53.5 56.6 36.7 55.4 660.5 121.4 72.5 64.1 218.3 42.5 146.2 129.9 168.2 43.5 230.6 119.7 56.3 86.5 55.4 67.1 292.8 179.3 72.4 24.4 58.4 54.2 120.7 125.9 93.2 58.2 80.0 57.7 151.7 120.0 39.9 155.3 40.2 216.2 228.6 137.1 97.7 52.6 36.7 131.2 42.4 58.3 136.2 93.9 93.5 46.6 85.6 194.9 55.8 159.6 67.9 206.0 91.8 53.4 48.4 291.6 126.9 262.3 362.6 512.6 278.1 247.3 0.2 31.1 106.3 84.1 303.8 0.0 87.2 256.0 0.9 15.3 268.2 25.3 187.4 185.8 0.1 0.7 45.4 152.4 182.3 203.2 4.0 97.8 60.4 0.1 0.5 28.5 263.3 45.4 26.5 80.2 662.8 329.9 74.6 122.6 56.1 58.0 42.7 47.3 263.9 349.9 235.4 473.9 91.8 184.2 167.1 65.4 27.4 823.3 122.7 25.9 0.7 18.5 1.2 33.5 95.9 80.3 17.1 9.9 15.7 0.1 11.7 0.1 0.0 1.0 0.2 8.1 0.1 2.8 0.4 5.4 0.1 10.3 7.4 0.2 6.9 56.6 55.4 72.5 64.1 55.4 67.1 58.4 54.2 57.7 52.6 58.3 55.8 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.4 0.0 0.0 0.0 0.0 42.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 125.7 25.2 0.0 0.0 0.0 0.0 0.0 0.0 73.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 219.7 0.0 0.0 0.0 0.0 GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 140.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 80.3;Hepatocytes: 66.1;Proximal tubular cells: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 22: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Nuclear speckles, Mitochondria" "HPA020460: AB_1849548, HPA063924: " "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.10e-2)" "unprognostic (4.17e-2)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (3.56e-2)" "unprognostic (2.76e-3)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-3)" "unprognostic (8.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.73e-3)" "unprognostic (3.99e-1)" 6.6 15.7 25.1 3.2 24.8 14.1 6.5 26.2 33.3 6.3 22.5 7.3 4.9 7.8 3.0 17.0 6.0 5.0 43.4 26.1 25.0 13.0 53.3 5.6 2.8 25.9 27.4 9.0 140.2 6.0 9.7 2.7 27.8 22.8 4.9 2.2 13.3 6.8 19.5 8.1 5.4 4.2 24.4 1.5 13.2 10.3 27.9 4.3 16.0 19.1 3.1 7.1 7.0 24.6 18.7 4.7 11.9 68.2 24.0 19.4 8.4 25.9 26.9 19.2 16.3 10.5 2.1 5.8 11.8 11.7 11.3 10.6 11.9 18.3 4.3 2.6 21.9 12.9 15.0 42.5 39.0 23.0 16.4 22.8 10.9 12.7 27.7 6.2 16.0 23.0 33.2 6.6 9.2 16.2 24.3 42.3 5.0 28.8 19.0 25.2 2.5 34.4 24.6 14.3 24.5 16.7 20.0 32.3 13.9 4.2 25.8 11.1 11.8 19.3 10.6 12.9 9.2 21.9 11.5 12.1 13.3 21.1 20.5 0.1 0.6 0.4 0.7 0.7 0.3 0.1 1.6 0.5 1.3 0.0 3.5 1.4 0.3 1.3 0.4 1.3 1.7 1.4 25.1 24.8 26.2 33.3 26.1 25.0 25.9 27.4 27.8 24.4 27.9 24.6 3.5 6.4 15.4 9.8 2.8 7.8 18.5 11.2 12.5 8.9 18.6 17.4 54.6 11.5 9.4 11.0 4.2 15.7 0.7 13.1 80.3 7.2 4.1 9.9 8.1 5.5 2.4 22.7 5.0 10.3 19.6 9.8 15.3 16.7 8.9 17.6 5.0 66.1 4.7 8.4 4.7 32.3 8.2 2.9 1.3 7.7 3.7 2.1 21.4 1.0 1.0 25.1 1.0 6.6 4.1 5.4 8.7 9.8 2.0 19.1 8.6 163.8 6.4 2.2 6.6 4.8 30.1 12.6 33.2 19.6 6.0 27.8 3.0 27.8 24.0 14.4 GALR3 ENSG00000128310 "Galanin receptor 3" O60755 22 37823382-37825485 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Glandular and luminal cells: 1.2;Late spermatids: 1.7;Paneth cells: 1.1;Theca cells: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 52: Non-specific - Transcription" "unprognostic (4.45e-2)" "unprognostic (1.45e-2)" "unprognostic (4.60e-3)" "unprognostic (7.07e-2)" "unprognostic (7.63e-2)" "unprognostic (8.17e-2)" "unprognostic (4.18e-2)" "unprognostic (2.16e-2)" "unprognostic (3.74e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-1)" "unprognostic (1.66e-2)" "unprognostic (7.37e-2)" "unprognostic (8.35e-2)" "unprognostic (4.45e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.4 0.1 0.5 0.1 0.2 0.2 0.1 0.8 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.9 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.2 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.5 0.0 0.0 0.0 1.5 0.2 0.1 ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 15: NK-cells - Transcription" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Microtubules, Midbody" Nucleoplasm "HPA071287: AB_2686380" "unprognostic (5.36e-2)" "prognostic favorable (2.06e-4)" "unprognostic (1.02e-1)" "prognostic favorable (7.38e-5)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.06e-1)" "unprognostic (3.41e-2)" "prognostic favorable (6.16e-4)" "unprognostic (2.53e-1)" "unprognostic (6.33e-2)" "unprognostic (1.13e-1)" "unprognostic (5.07e-2)" "unprognostic (1.89e-1)" "unprognostic (3.02e-3)" 8.6 18.7 22.4 5.9 20.8 6.9 9.1 22.6 23.3 13.0 28.7 16.4 7.1 12.9 7.8 14.0 23.8 6.3 12.4 23.0 26.2 14.9 15.6 8.4 6.4 22.6 24.7 17.8 18.1 11.7 19.2 5.4 21.6 13.7 6.6 6.3 13.9 11.0 12.6 11.3 8.9 9.5 22.0 9.2 10.9 30.9 26.1 10.4 13.8 8.7 7.2 14.0 10.9 20.3 18.5 18.6 15.4 23.0 19.9 11.3 8.1 24.8 19.2 41.1 25.2 11.8 7.3 17.8 10.1 16.5 13.3 16.4 19.5 14.1 19.9 14.2 39.5 9.3 17.3 28.3 17.7 17.8 20.8 10.1 14.2 22.6 13.3 10.3 25.5 13.1 11.9 12.7 19.1 19.8 17.6 21.1 4.4 24.5 16.5 20.2 18.3 11.3 23.2 6.4 26.4 14.1 20.7 18.8 30.8 7.0 19.3 28.0 15.1 24.5 25.6 12.9 18.6 13.3 11.7 14.3 20.1 15.1 17.9 3.5 4.5 2.2 5.4 5.5 5.4 3.9 5.1 4.0 5.7 5.2 5.3 2.6 2.7 10.2 9.3 5.3 2.4 3.3 22.4 20.8 22.6 23.3 23.0 26.2 22.6 24.7 21.6 22.0 26.1 20.3 8.4 12.8 14.5 11.8 14.4 15.8 11.0 12.4 12.0 18.3 16.9 15.6 8.1 24.3 12.2 18.4 29.2 20.9 14.0 19.9 39.2 17.1 6.4 47.8 12.6 10.9 9.0 12.8 9.4 14.7 17.7 12.3 12.2 8.5 9.5 23.3 13.6 12.0 13.2 26.9 9.4 14.3 12.2 12.5 10.7 7.7 18.0 8.8 10.6 2.8 9.2 18.5 17.5 13.6 8.6 11.3 15.3 21.4 8.4 11.4 19.2 22.0 48.2 23.2 6.6 13.1 13.4 65.6 42.1 12.7 17.6 16.8 13.3 25.4 20.7 9.9 EIF3L "EIF3EIP, EIF3S11, EIF3S6IP, HSPC021, HSPC025" ENSG00000100129 "Eukaryotic translation initiation factor 3 subunit L" Q9Y262 22 37848868-37889407 "Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003028 Approved Approved Nucleoplasm,Nucleoli NA NA 72000 "Cluster 44: Non-specific - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Nucleoplasm "HPA003028: AB_1078726" "unprognostic (2.07e-2)" "unprognostic (3.02e-2)" "unprognostic (5.06e-3)" "unprognostic (3.20e-1)" "unprognostic (3.79e-3)" "unprognostic (9.86e-2)" "unprognostic (1.35e-1)" "unprognostic (9.65e-2)" "unprognostic (2.66e-1)" "unprognostic (5.81e-3)" "unprognostic (2.35e-1)" "unprognostic (9.74e-2)" "prognostic favorable (6.11e-4)" "unprognostic (1.48e-1)" "unprognostic (1.42e-1)" "unprognostic (2.42e-1)" "unprognostic (2.03e-3)" 97.1 80.1 22.7 37.1 22.8 86.3 149.4 25.4 33.6 113.2 22.8 105.4 56.9 85.1 41.9 84.0 100.4 21.2 76.6 23.4 22.2 101.2 64.4 56.9 52.1 22.5 22.8 200.2 257.9 36.7 64.0 52.8 22.7 71.5 63.4 26.8 92.2 78.3 162.0 123.7 73.3 42.2 22.0 57.6 143.9 34.8 23.4 44.3 87.3 43.1 82.1 90.1 86.8 24.0 74.9 44.1 113.7 83.4 107.4 238.0 81.5 69.4 165.4 109.1 147.5 71.6 53.5 253.7 19.2 81.5 38.3 46.1 127.2 96.0 127.1 34.1 211.2 90.0 56.6 33.4 66.9 240.5 73.6 128.8 106.9 81.7 120.7 189.5 138.1 82.4 75.5 67.6 127.4 30.2 65.5 112.0 65.5 90.0 106.7 73.1 156.0 76.0 82.2 44.3 82.4 129.1 68.9 80.1 88.7 127.6 60.7 95.4 67.4 68.3 81.6 42.1 57.1 40.5 68.3 97.0 64.0 103.9 57.1 46.5 162.0 42.4 81.4 148.1 134.2 131.7 116.9 98.2 241.1 113.1 161.8 125.5 22.8 111.3 129.4 116.9 124.2 299.1 22.7 22.8 25.4 33.6 23.4 22.2 22.5 22.8 22.7 22.0 23.4 24.0 128.9 118.6 210.9 16.6 299.0 397.0 491.6 449.3 278.9 61.3 366.9 299.8 2.5 217.3 238.0 66.2 29.2 699.0 255.0 77.5 416.7 234.3 137.6 94.8 159.4 171.1 197.3 277.2 18.9 461.8 628.9 166.1 101.9 108.3 222.3 318.1 183.1 116.1 256.6 25.2 23.2 236.3 187.2 299.7 418.0 341.2 222.4 229.8 227.7 11.2 447.0 149.1 216.3 11.6 19.3 212.4 211.4 212.1 170.5 306.2 180.7 328.2 90.2 51.1 164.3 278.3 267.4 121.9 128.5 301.9 429.6 703.2 221.6 239.9 378.4 435.0 MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" 9.6 5.8 8.2 9.3 14.8 6.2 10.2 15.7 10.3 18.4 8.0 38.6 6.4 28.4 3.1 46.6 13.6 6.4 10.7 8.7 9.8 8.7 7.0 11.7 5.9 19.7 16.8 4.8 18.5 10.6 4.4 17.3 17.4 17.0 4.6 0.8 17.8 24.0 10.8 36.6 12.5 19.7 14.1 7.2 44.0 10.8 15.3 5.4 10.0 5.2 7.1 25.4 26.0 22.2 25.4 13.7 13.0 15.4 10.4 11.9 59.9 32.3 17.5 34.8 25.3 17.3 13.1 10.8 10.5 22.2 22.7 65.0 9.1 69.9 17.2 21.2 31.3 5.7 11.6 16.7 24.0 11.6 11.8 11.3 101.2 42.5 70.1 10.4 22.1 4.9 8.9 8.1 22.7 10.6 2.9 6.7 5.0 12.9 12.1 16.6 27.4 6.1 8.1 53.0 9.6 8.5 19.3 19.7 20.2 15.4 10.8 10.9 34.3 61.1 47.3 37.8 27.5 9.4 3.7 7.2 55.2 5.8 29.0 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.3 0.5 0.3 0.5 0.3 0.2 0.5 0.5 0.1 0.6 0.1 0.4 8.2 14.8 15.7 10.3 8.7 9.8 19.7 16.8 17.4 14.1 15.3 22.2 10.9 0.0 7.8 1.3 4.8 7.5 10.1 12.8 23.9 0.7 7.3 7.9 11.9 7.2 9.5 5.5 0.0 31.0 7.8 7.7 1.9 10.5 18.1 11.3 5.4 12.2 3.5 1.3 0.7 10.2 26.3 4.3 27.5 6.8 1.3 5.8 6.4 5.9 8.7 5.0 4.4 3.9 6.1 4.4 3.4 28.8 1.8 4.3 1.8 1.0 7.2 0.7 7.2 2.5 17.8 15.4 2.2 4.1 6.4 13.6 4.4 2.7 6.0 0.7 0.0 3.5 9.4 5.5 2.2 27.2 9.1 39.4 5.2 1.5 3.7 15.2 C22orf23 "EVG1, FLJ32787, LOC84645" ENSG00000128346 "Chromosome 22 open reading frame 23" Q9BZE7 22 37943050-37953669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 95.5" "Group enriched" "Detected in some" 7 "Early spermatids: 292.5;Late spermatids: 312.9;Spermatocytes: 241.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 31.8;U-138 MG: 31.4;U-87 MG: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000650 Approved Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "HPA000650: AB_2732391" "unprognostic (6.09e-3)" "unprognostic (3.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.95e-1)" "unprognostic (1.80e-1)" "unprognostic (7.42e-5)" "unprognostic (1.50e-2)" "unprognostic (2.60e-1)" "unprognostic (2.72e-2)" "unprognostic (1.04e-1)" "unprognostic (5.80e-2)" "unprognostic (8.18e-3)" "unprognostic (4.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.82e-2)" "unprognostic (8.46e-2)" 2.9 2.6 3.9 5.6 8.8 3.0 0.8 9.5 5.1 1.7 4.7 3.4 2.9 8.3 1.3 14.0 12.4 6.4 5.1 4.7 7.7 2.3 0.4 5.0 3.6 12.8 10.4 2.5 8.6 1.1 4.8 5.3 11.0 5.0 0.1 3.5 10.3 0.2 5.7 26.0 3.8 0.1 8.2 2.3 9.0 95.5 9.7 0.2 8.2 0.0 0.1 6.2 1.2 16.1 6.6 5.3 11.1 10.3 0.2 0.4 13.7 18.4 0.5 0.5 0.7 6.3 5.9 3.5 5.0 0.4 11.7 31.8 0.4 0.1 0.6 6.7 13.4 2.0 4.6 4.3 0.5 5.4 4.4 0.4 0.2 2.2 0.2 15.4 0.1 2.6 2.3 2.0 0.1 4.1 0.3 3.2 1.6 6.6 4.6 6.0 16.1 1.3 0.1 29.4 5.6 4.0 8.2 3.2 10.3 17.5 3.6 7.3 27.8 31.4 10.2 25.1 10.0 4.6 2.0 1.6 46.9 2.5 18.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.8 9.5 5.1 4.7 7.7 12.8 10.4 11.0 8.2 9.7 16.1 0.2 0.0 2.4 1.3 0.0 0.3 0.1 1.8 0.0 0.2 0.3 0.8 0.1 1.5 1.9 0.0 0.0 0.1 0.1 0.1 1.9 0.4 292.5 16.8 0.6 0.6 0.0 0.0 0.5 0.4 0.1 0.5 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 312.9 6.8 0.5 0.0 1.0 0.0 2.2 0.0 1.0 5.6 0.3 0.0 5.3 0.0 0.1 0.0 1.8 37.8 1.2 0.0 0.5 0.4 241.3 5.2 0.0 0.0 0.0 0.2 0.3 0.0 0.1 POLR2F "HRBP14.4, RPB6" ENSG00000100142 "RNA polymerase II, I and III subunit F" P61218 22 37952607-38041915 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 4 "melanoma: 1.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000827, CAB009882" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "CAB009882: AB_2299942, HPA000827: AB_1079834" "unprognostic (8.27e-2)" "unprognostic (7.50e-2)" "unprognostic (1.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.35e-1)" "unprognostic (2.09e-1)" "unprognostic (2.73e-3)" "unprognostic (2.85e-1)" "unprognostic (5.87e-2)" "unprognostic (4.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.11e-4)" "unprognostic (9.08e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-1)" "unprognostic (7.86e-2)" 52.5 61.1 73.4 34.6 92.3 38.9 50.8 77.5 90.2 59.5 56.9 64.9 37.7 53.2 24.8 58.7 50.2 19.5 91.8 74.2 91.2 58.2 118.6 41.6 31.0 87.9 83.9 60.9 47.5 76.5 62.7 30.2 82.6 47.7 28.7 16.8 56.1 39.6 111.0 45.8 42.3 28.8 75.3 36.4 57.6 48.8 86.8 36.7 54.7 68.4 26.3 53.1 52.7 123.7 150.7 176.2 120.6 128.7 141.1 81.7 109.4 138.0 81.0 141.4 130.5 210.0 51.8 117.4 99.1 120.3 138.3 106.4 166.9 135.7 67.1 143.0 303.7 107.3 181.3 289.1 125.9 213.6 67.0 112.4 99.8 186.3 72.1 71.2 118.7 130.4 208.9 93.7 101.9 220.2 168.4 258.2 174.3 175.4 134.7 162.3 110.4 134.5 77.4 94.8 180.6 67.2 129.5 88.9 215.3 69.6 62.9 144.3 110.5 119.8 173.9 150.4 158.1 106.0 178.0 247.9 122.4 107.9 138.4 118.9 92.9 140.8 83.8 90.4 78.5 95.8 71.9 81.8 86.3 71.3 63.1 63.7 122.8 113.7 78.5 123.3 103.4 85.3 73.4 92.3 77.5 90.2 74.2 91.2 87.9 83.9 82.6 75.3 86.8 123.7 82.6 38.5 85.9 9.4 73.2 204.3 113.9 205.4 63.7 26.7 133.8 168.7 0.3 101.5 122.5 121.4 25.0 243.5 70.5 148.7 193.7 160.0 117.0 96.0 117.2 94.8 117.2 109.6 9.9 159.5 303.4 97.4 58.1 82.4 90.0 90.0 98.6 304.4 178.5 28.6 10.7 143.1 116.0 94.2 102.9 42.0 159.7 65.9 225.9 2.8 102.3 99.4 111.2 9.5 99.0 182.4 152.9 151.2 65.7 137.3 196.6 306.5 114.3 33.3 157.8 90.1 197.1 237.0 241.0 106.0 224.3 211.9 82.4 82.7 145.7 121.2 SOX10 "DOM, WS2E, WS4" ENSG00000100146 "SRY-box transcription factor 10" P56693 22 37970686-37987422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Hirschsprung disease, Kallmann syndrome, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 194.9;salivary gland: 114.3" "Group enriched" "Detected in some" 14 "Breast glandular cells: 32.3;Breast myoepithelial cells: 47.8;Melanocytes: 35.6;Oligodendrocyte precursor cells: 61.3;Oligodendrocytes: 59.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 510 "SK-MEL-30: 313.9;WM-115: 432.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003171, HPA068898" Enhanced Supported Nucleoplasm Yes NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "CAB003171: AB_2195374, HPA068898: AB_2686054" 2.9 2.7 76.9 2.5 133.7 0.1 21.7 103.1 102.8 11.8 24.9 26.6 1.5 0.8 1.2 2.7 2.5 2.2 8.8 82.7 89.0 0.5 0.5 0.1 0.0 134.7 114.0 1.2 0.8 0.0 1.8 0.0 123.3 6.8 2.6 0.5 114.3 5.8 0.6 17.0 7.1 1.9 87.3 0.3 6.1 2.7 114.2 0.0 0.9 1.5 0.0 8.4 9.5 194.9 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.9 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.3 0.1 0.7 0.0 432.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.9 133.7 103.1 102.8 82.7 89.0 134.7 114.0 123.3 87.3 114.2 194.9 0.3 0.0 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.0 32.3 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.4 0.9 0.1 35.6 0.0 0.0 0.0 0.0 61.3 59.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.3 0.7 0.0 0.9 0.0 0.2 0.0 0.0 0.0 PICK1 "dJ1039K5, MGC15204, PRKCABP" ENSG00000100151 "Protein interacting with PRKCA 1" Q9NRD5 22 38056311-38075701 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 116.1;Late spermatids: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000819, HPA072674" Approved Supported Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "HPA000819: , HPA072674: AB_2686547" "unprognostic (1.97e-2)" "unprognostic (4.61e-3)" "unprognostic (7.79e-2)" "unprognostic (9.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.81e-1)" "unprognostic (6.04e-2)" "unprognostic (1.65e-2)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-3)" "unprognostic (1.20e-1)" "unprognostic (8.56e-2)" "prognostic favorable (5.26e-5)" "unprognostic (1.36e-1)" "unprognostic (2.74e-1)" "unprognostic (4.61e-3)" 8.8 14.9 12.4 4.8 15.2 5.4 13.5 12.8 20.3 9.9 12.9 11.9 10.1 11.7 13.8 15.9 16.3 8.9 18.2 14.5 13.5 15.1 17.5 10.8 5.4 14.5 13.6 15.4 18.5 29.3 28.8 6.7 16.7 25.6 12.2 5.9 18.6 12.6 26.3 16.9 11.3 11.3 11.6 10.1 16.2 27.4 15.6 5.9 14.6 16.2 8.2 9.3 12.0 23.0 19.5 13.7 7.6 10.0 5.3 4.1 11.3 10.7 12.8 22.5 22.7 14.6 12.0 8.6 11.6 13.0 17.0 20.8 21.0 43.2 19.3 5.3 33.6 3.1 16.8 17.1 19.3 10.1 20.4 13.3 24.9 14.8 21.9 22.8 8.8 11.1 6.4 6.2 4.7 12.4 6.0 0.9 12.1 44.3 14.9 5.1 0.3 7.8 25.8 31.1 31.5 16.0 12.0 28.8 11.1 11.1 16.8 7.3 2.4 6.4 12.0 8.6 6.4 13.9 3.4 2.7 13.8 3.4 9.4 0.0 0.9 0.0 0.5 0.4 0.2 0.3 0.5 1.0 1.6 1.1 1.0 0.5 0.6 0.4 0.5 0.3 0.7 0.6 12.4 15.2 12.8 20.3 14.5 13.5 14.5 13.6 16.7 11.6 15.6 23.0 8.1 9.6 10.6 11.1 8.1 8.0 14.2 15.6 12.0 12.7 18.7 16.1 10.2 11.5 12.1 7.3 8.4 26.1 6.0 25.4 11.7 18.8 116.1 15.4 3.6 7.8 10.3 1.7 26.8 15.7 14.8 6.8 29.6 17.3 8.9 36.3 5.7 9.7 15.1 20.2 19.4 20.1 18.3 31.5 13.3 85.5 11.1 16.3 7.2 6.5 16.0 13.6 8.2 8.5 29.0 21.4 18.5 17.0 5.8 22.1 18.3 16.0 12.8 12.5 13.1 6.0 9.5 17.2 6.7 12.0 9.7 38.4 6.8 15.5 18.5 14.7 SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084093 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 9.1" "Cell type enhanced" "Detected in some" "Leydig cells: 4.4;Melanocytes: 5.4;Oligodendrocytes: 4.0;Spermatogonia: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;SiHa: 2.1;T-47d: 1.3;U-2 OS: 1.2;U-266/70: 4.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Intermediate filaments" "HPA075017: AB_2732276" "unprognostic (1.22e-2)" "unprognostic (2.25e-2)" "unprognostic (5.07e-6)" "unprognostic (2.99e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-2)" "unprognostic (2.99e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.63e-2)" "unprognostic (1.32e-2)" "unprognostic (2.34e-4)" "unprognostic (7.69e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-1)" "unprognostic (9.71e-5)" 0.5 0.3 1.1 0.0 3.3 0.2 0.6 0.2 6.0 0.7 0.0 0.3 0.1 0.4 0.0 0.3 0.9 0.1 0.6 0.8 1.1 0.4 0.2 0.3 0.0 4.0 1.4 0.3 0.4 0.0 1.6 0.0 3.6 1.7 0.0 0.1 1.2 0.0 0.5 0.7 0.2 0.0 0.3 0.3 0.4 0.8 2.8 0.0 0.7 0.0 0.0 0.4 0.7 9.1 0.3 0.0 0.1 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.7 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.4 0.1 2.1 0.0 0.2 0.1 1.3 0.0 0.0 0.0 1.2 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.3 0.2 6.0 0.8 1.1 4.0 1.4 3.6 0.3 2.8 9.1 0.6 0.0 0.0 0.7 0.0 1.3 0.5 0.6 0.6 0.1 0.6 0.8 0.7 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 1.3 0.1 0.9 0.2 0.0 0.0 0.4 0.0 0.0 2.2 0.0 0.4 0.0 1.7 0.7 0.1 1.0 0.0 0.4 0.2 0.0 0.8 1.4 2.5 4.4 0.7 5.4 0.0 0.0 1.4 0.0 0.5 4.0 0.3 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.7 0.0 1.5 2.4 2.1 7.7 0.5 0.9 0.0 0.3 0.6 0.1 0.7 BAIAP2L2 "FLJ22582, pinkbar" ENSG00000128298 "BAR/IMD domain containing adaptor protein 2 like 2" Q6UXY1 22 38084652-38111015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 98.6;kidney: 42.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 68.2;Intestinal goblet cells: 58.4;Oligodendrocytes: 31.0;Paneth cells: 32.6;Proximal enterocytes: 125.8;Undifferentiated cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 14.1;OE19: 44.2;RPTEC TERT1: 27.3;SK-MEL-30: 38.4;WM-115: 29.8" "Region enhanced" "Detected in many" "olfactory bulb: 3.7" "Low region specificity" "Detected in many" HPA003043 Approved NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "HPA003043: AB_2227864" "unprognostic (2.15e-1)" "unprognostic (4.23e-2)" "unprognostic (9.82e-2)" "unprognostic (5.91e-2)" "unprognostic (7.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.57e-3)" "unprognostic (1.37e-3)" "unprognostic (2.30e-2)" "unprognostic (2.14e-1)" "unprognostic (1.21e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (5.73e-2)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (4.51e-2)" 2.5 1.1 3.1 2.8 3.0 0.1 1.8 2.6 6.1 3.7 2.8 41.0 98.6 2.1 0.4 9.7 1.9 14.9 0.8 3.1 2.6 42.5 3.7 0.9 0.3 2.8 2.8 1.5 2.7 0.1 3.5 0.2 2.9 2.5 12.7 0.4 1.9 0.3 1.2 2.4 81.6 0.8 2.6 1.4 8.5 5.9 2.7 0.6 3.1 0.1 0.4 1.2 3.4 3.7 0.2 12.3 0.0 0.0 0.3 1.9 1.5 3.0 0.0 0.0 0.2 9.6 0.8 0.2 4.6 2.7 0.0 1.6 0.0 0.4 0.0 0.3 0.4 0.9 0.0 14.1 0.6 0.0 0.8 0.3 0.7 7.0 0.5 0.0 0.0 0.5 0.4 0.0 0.1 0.1 0.6 0.3 1.1 44.2 0.0 0.4 0.0 0.8 27.3 0.1 0.2 0.2 0.0 5.3 38.4 0.1 0.3 0.2 0.1 0.1 0.4 0.0 0.0 0.9 0.1 0.2 0.0 0.0 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 3.0 2.6 6.1 3.1 2.6 2.8 2.8 2.9 2.6 2.7 3.7 0.2 0.0 0.0 7.8 0.5 0.8 0.2 1.0 1.2 2.8 0.3 0.3 1.1 17.2 0.2 0.0 2.1 0.3 0.2 68.2 1.9 0.6 0.7 2.2 3.8 0.3 27.6 0.0 17.2 0.0 1.2 0.8 21.9 12.8 0.0 0.5 0.4 0.9 0.5 6.7 13.1 58.4 0.0 0.3 0.2 0.5 1.2 0.2 5.4 5.6 0.1 0.2 1.0 7.5 31.0 5.4 32.6 1.2 0.3 0.2 125.8 19.1 0.1 1.4 0.0 0.2 1.3 1.3 4.4 1.4 1.1 0.4 0.5 0.3 41.4 0.5 PLA2G6 "iPLA2, iPLA2beta, NBIA2, PARK14, PNPLA9" ENSG00000184381 "Phospholipase A2 group VI" O60733 22 38111495-38214778 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Lipid metabolism, Phospholipid metabolism" "Calmodulin-binding, Hydrolase" "Disease variant, Dystonia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 28.5;Spermatocytes: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 39.1;HMC-1: 25.6;U-266/70: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001171 Approved Approved "Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite, Cytosol" "HPA001171: AB_1079145" "unprognostic (5.26e-2)" "prognostic favorable (7.29e-4)" "unprognostic (8.74e-2)" "unprognostic (6.27e-2)" "unprognostic (3.83e-1)" "unprognostic (3.70e-3)" "unprognostic (8.67e-3)" "unprognostic (9.55e-2)" "unprognostic (3.48e-1)" "unprognostic (1.91e-1)" "unprognostic (2.37e-3)" "unprognostic (4.95e-2)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (3.00e-1)" "unprognostic (1.48e-1)" "prognostic favorable (1.55e-4)" 20.0 22.2 14.1 4.6 16.6 12.2 19.5 15.2 20.3 24.9 12.3 11.4 9.2 17.8 10.6 10.3 26.2 13.2 9.5 14.3 13.7 24.0 13.3 10.4 8.5 17.2 15.0 24.3 16.1 6.7 17.7 4.1 19.5 24.9 2.8 8.3 15.9 9.2 10.7 17.2 12.5 3.4 15.3 17.1 13.2 42.1 15.4 11.7 51.8 4.4 4.6 13.2 14.4 25.5 0.8 1.3 2.6 6.3 8.0 5.5 9.8 0.9 1.0 0.5 1.2 3.2 2.4 5.9 6.7 1.3 0.9 3.5 2.2 2.5 0.3 9.2 11.1 39.1 3.4 3.5 3.1 2.6 25.6 13.3 3.7 2.3 4.6 6.6 0.8 11.7 8.0 13.3 0.7 3.1 8.5 3.0 3.4 2.7 1.3 6.5 1.2 6.1 2.8 5.9 7.1 1.9 1.9 3.1 6.7 3.9 4.1 2.4 0.6 2.1 4.5 0.9 0.6 20.6 2.7 4.0 4.0 3.2 2.0 1.4 0.1 0.0 1.0 0.0 0.7 0.5 1.0 1.5 0.4 0.3 0.4 1.2 0.6 3.7 0.2 1.3 1.6 0.7 14.1 16.6 15.2 20.3 14.3 13.7 17.2 15.0 19.5 15.3 15.4 25.5 5.6 3.2 2.7 19.9 4.6 3.1 3.5 4.0 4.6 9.9 7.4 6.5 2.0 4.3 5.0 12.9 4.2 3.3 11.1 11.3 0.0 2.1 28.5 9.5 4.4 3.1 11.4 7.4 6.4 1.0 2.7 3.3 11.2 8.7 0.0 10.6 3.6 3.5 1.7 15.2 5.9 8.6 2.0 1.0 0.8 18.3 5.9 2.1 1.8 4.7 2.3 4.9 8.2 4.5 25.2 1.1 12.6 3.8 4.7 2.9 21.9 1.9 7.6 7.5 6.6 2.6 3.4 44.5 7.7 4.1 3.4 4.9 6.6 6.8 8.4 2.1 MAFF hMafF ENSG00000185022 "MAF bZIP transcription factor F" Q9ULX9 22 38200767-38216507 "Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 682.0;Syncytiotrophoblasts: 479.1;Urothelial cells: 409.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 23.9;neutrophil: 8.7;NK-cell: 21.1" "Group enriched" "Detected in many" 6 "granulocytes: 23.9;NK-cells: 21.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 79.2;SK-MEL-30: 104.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 5.6" "CAB025341, HPA055371" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 10: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Mitochondria "CAB025341: , HPA055371: AB_2682797" "prognostic favorable (4.32e-4)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "unprognostic (2.13e-3)" "unprognostic (5.06e-3)" "unprognostic (3.42e-3)" "unprognostic (7.83e-3)" "unprognostic (5.36e-3)" "unprognostic (1.23e-3)" "unprognostic (2.44e-1)" "unprognostic (3.24e-2)" "unprognostic (2.84e-1)" "unprognostic (4.08e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-2)" 102.9 22.8 9.4 12.9 9.0 36.2 69.9 9.3 10.7 37.4 9.4 26.6 8.1 28.8 2.1 53.4 64.2 41.4 53.8 8.2 11.9 32.0 30.8 59.2 4.7 14.5 10.0 53.9 19.7 5.3 19.5 34.5 13.4 39.5 10.3 19.6 28.6 5.5 73.3 45.7 19.6 23.2 10.5 9.3 45.4 3.0 14.1 7.4 25.0 6.9 11.3 53.8 41.4 16.6 20.8 3.3 4.4 6.6 6.9 21.3 20.6 41.4 54.2 19.8 21.0 6.1 16.0 0.7 3.9 16.9 29.5 13.5 1.1 15.7 33.2 3.9 0.6 2.1 2.1 5.2 18.0 1.3 7.1 9.3 25.7 79.2 43.6 17.6 42.1 1.9 4.2 18.6 15.6 4.9 0.8 5.2 3.3 22.0 16.8 1.4 3.8 4.3 19.9 30.6 2.2 3.7 6.1 15.4 104.9 10.7 3.3 1.5 57.9 24.7 19.2 18.8 13.7 7.2 8.0 0.7 37.4 1.4 15.9 23.9 0.4 0.3 2.9 0.7 2.8 0.8 1.7 2.1 1.4 0.5 2.1 1.6 8.7 21.1 3.5 0.2 0.7 1.8 9.4 9.0 9.3 10.7 8.2 11.9 14.5 10.0 13.4 10.5 14.1 16.6 215.4 54.5 43.4 1.0 19.3 125.9 344.1 56.8 169.0 2.9 302.9 214.1 18.6 67.2 49.5 11.0 0.0 37.8 112.5 134.2 7.9 49.9 0.5 284.7 149.3 97.3 104.8 5.7 0.8 24.2 77.5 134.7 132.5 682.0 22.2 11.5 22.1 8.2 26.0 0.0 1.6 112.5 34.6 14.0 131.1 0.4 9.9 113.5 58.7 1.0 10.2 36.0 17.5 1.5 1.3 76.0 181.0 3.8 25.8 258.4 67.6 3.7 37.9 3.6 19.7 265.2 153.1 2.4 1.0 139.5 103.1 479.1 59.0 8.4 75.5 409.2 TMEM184B "C22orf5, DKFZP586A1024, FM08, HS5O6A" ENSG00000198792 "Transmembrane protein 184B" Q9Y519 22 38219291-38273010 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 86.8;Oligodendrocytes: 93.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/84: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024076 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus, Cytosol" Nucleoplasm "HPA024076: AB_1858106" "unprognostic (1.52e-1)" "unprognostic (9.17e-2)" "unprognostic (1.86e-1)" "unprognostic (8.96e-2)" "unprognostic (3.82e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (5.94e-6)" "unprognostic (1.14e-2)" "unprognostic (5.18e-2)" "unprognostic (4.52e-2)" "unprognostic (9.20e-2)" "unprognostic (1.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (2.96e-1)" 28.6 21.9 49.5 14.0 52.3 5.8 24.9 54.5 59.6 18.6 22.1 21.0 16.9 19.4 7.2 17.3 17.1 14.5 35.7 49.6 48.2 25.9 11.4 35.9 8.4 56.8 56.0 16.2 18.4 18.9 34.3 38.4 54.8 18.8 10.8 15.2 22.6 14.4 28.7 16.0 17.6 14.0 52.9 22.0 22.4 7.5 56.7 6.2 26.1 17.4 8.2 18.4 16.5 66.9 55.8 47.5 27.5 21.9 53.6 42.6 63.4 58.8 82.9 46.9 41.5 35.1 25.2 10.6 44.9 87.6 42.4 67.2 24.9 57.8 31.6 37.9 45.0 20.9 34.0 29.5 56.3 16.6 28.0 36.1 50.2 55.4 61.5 48.5 59.5 15.9 13.5 36.2 41.5 31.6 10.6 14.1 22.4 41.2 43.4 18.1 24.8 10.6 34.8 60.6 59.3 10.5 44.2 63.6 32.0 31.7 35.2 12.0 89.2 47.7 48.4 42.5 36.2 74.5 197.9 8.5 69.2 12.1 42.0 14.2 3.3 4.7 5.3 2.3 4.6 1.4 2.9 4.0 4.5 1.1 2.1 2.5 10.9 6.2 1.6 7.0 1.0 3.2 49.5 52.3 54.5 59.6 49.6 48.2 56.8 56.0 54.8 52.9 56.7 66.9 43.4 6.4 14.8 86.8 7.5 12.4 19.8 22.3 17.6 16.4 15.9 10.5 17.1 8.6 18.7 14.7 2.1 35.0 17.8 12.5 3.9 17.3 5.6 17.4 15.5 34.6 25.9 4.6 42.6 22.2 48.3 17.4 13.3 33.8 2.5 15.3 18.2 4.4 14.7 15.2 40.7 19.7 12.2 8.5 19.7 2.4 11.8 8.4 14.2 22.5 12.2 44.4 23.7 42.3 93.1 28.3 9.8 13.5 35.6 32.9 11.1 4.3 15.9 9.0 19.7 15.3 27.0 3.3 6.1 5.3 9.7 78.4 9.3 10.2 10.1 37.0 CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 280.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 15.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "CAB009626: AB_2084517, HPA026288: AB_1847276" "unprognostic (2.32e-1)" "unprognostic (8.41e-2)" "unprognostic (5.14e-2)" "unprognostic (5.01e-3)" "unprognostic (1.95e-2)" "unprognostic (4.50e-3)" "prognostic unfavorable (8.20e-5)" "unprognostic (2.08e-3)" "unprognostic (3.69e-1)" "unprognostic (1.22e-1)" "unprognostic (9.63e-2)" "unprognostic (4.16e-3)" "prognostic unfavorable (4.67e-6)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "unprognostic (2.58e-1)" "unprognostic (3.25e-3)" 87.1 52.8 81.1 41.2 82.6 51.6 88.3 80.8 95.1 93.6 66.0 73.0 41.4 82.7 52.5 69.0 83.3 48.7 80.9 82.9 73.7 70.2 37.4 92.2 40.3 78.9 78.6 109.5 64.9 74.1 85.1 71.2 79.5 80.3 35.5 47.3 71.6 44.9 60.5 94.8 50.9 45.3 70.2 63.6 58.0 29.5 83.2 33.3 64.4 47.2 37.8 65.7 88.4 93.9 101.5 57.4 121.6 114.7 61.5 88.3 92.1 126.9 168.6 116.7 114.3 63.9 76.7 74.2 53.0 120.7 70.7 77.9 96.1 177.9 79.2 123.0 215.2 23.9 181.2 47.4 123.7 48.3 61.9 90.2 143.8 171.7 220.3 141.0 121.1 60.6 50.9 155.0 110.8 68.4 71.1 60.9 87.2 67.3 69.1 130.8 90.1 123.4 99.0 92.4 181.6 69.3 102.9 109.3 124.7 68.0 59.5 73.0 134.3 94.0 111.3 58.7 102.1 61.2 105.2 104.5 151.0 56.9 176.3 4.8 1.6 3.6 3.0 0.8 3.8 2.1 3.4 3.0 1.8 3.1 1.9 2.5 3.8 5.7 0.5 15.9 1.6 1.2 81.1 82.6 80.8 95.1 82.9 73.7 78.9 78.6 79.5 70.2 83.2 93.9 73.4 38.5 21.7 0.0 32.3 78.6 158.8 89.1 68.9 132.6 53.7 42.4 49.8 34.3 73.9 23.9 60.5 35.2 42.3 28.4 7.9 30.8 46.0 94.3 72.5 76.4 62.8 12.6 0.0 41.8 49.2 60.8 39.8 126.5 3.8 46.6 45.0 21.3 23.1 72.3 0.0 46.0 46.8 17.6 54.1 69.1 85.4 21.8 60.5 0.0 13.3 117.9 28.8 0.0 0.0 57.5 33.1 66.2 83.5 160.5 9.0 6.5 62.8 60.7 72.3 85.7 98.0 8.0 20.0 50.3 104.7 125.5 26.0 34.9 37.6 280.8 TPTEP2-CSNK1E ENSG00000283900 "TPTEP2-CSNK1E readthrough" 22 38291918-38398522 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.4;B-cells: 1.8;Breast glandular cells: 1.9;Collecting duct cells: 9.2;Endometrial ciliated cells: 2.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 4.0;plasmacytoid DC: 3.5" "Group enriched" "Detected in many" 5 "dendritic cells: 3.5;granulocytes: 4.0" "Cell line enhanced" "Detected in many" "AF22: 5.2;Karpas-707: 9.1;U-266/70: 6.4" HPA026288 Uncertain NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "HPA026288: AB_1847276" 2.9 0.5 0.9 0.7 2.0 2.4 2.8 1.0 1.8 2.5 0.7 1.2 0.3 2.5 0.8 1.0 2.8 0.9 2.1 1.1 2.0 1.1 0.7 1.9 0.5 1.3 1.2 1.0 0.6 2.3 1.5 1.1 1.1 1.2 0.3 2.2 1.6 0.6 1.5 1.7 0.9 0.9 1.2 0.9 0.9 1.3 1.4 0.3 1.8 0.9 1.3 1.3 1.4 2.5 0.7 0.0 5.2 0.5 0.8 1.2 0.7 1.5 4.7 0.7 0.7 0.0 0.4 0.0 0.8 1.2 0.7 0.7 0.5 0.7 0.8 3.5 1.4 0.6 2.6 0.2 0.8 1.4 1.1 0.9 2.2 0.2 0.2 3.5 1.5 0.3 0.5 9.1 0.3 0.2 0.0 0.4 0.6 0.0 0.0 1.2 0.8 2.3 0.7 0.0 0.9 0.3 0.2 0.1 1.9 1.5 0.1 0.5 4.3 0.0 0.7 0.1 0.0 6.4 4.8 1.8 1.7 0.5 0.6 0.4 0.2 4.0 0.0 0.0 0.0 0.7 0.3 0.0 0.3 0.3 0.0 0.0 1.1 0.7 0.0 3.5 0.7 0.1 0.9 2.0 1.0 1.8 1.1 2.0 1.3 1.2 1.1 1.2 1.4 2.5 2.4 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.0 9.2 0.0 0.0 0.8 0.0 0.0 0.9 0.0 2.0 1.0 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 KCNJ4 "HIR, hIRK2, HRK1, IRK3, Kir2.3" ENSG00000168135 "Potassium inwardly rectifying channel subfamily J member 4" P48050 22 38426327-38455199 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "brain: 28.9;heart muscle: 33.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.3;Excitatory neurons: 14.3;Horizontal cells: 10.1;Inhibitory neurons: 11.1;Microglial cells: 3.7;Muller glia cells: 6.2" "Cancer enhanced" "Detected in some" "glioma: 2.1;liver cancer: 1.8" "Group enriched" "Detected in many" 5 "amygdala: 10.5;basal ganglia: 18.9;cerebral cortex: 28.9;hippocampal formation: 21.9;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SCLC-21H: 11.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 14 "amygdala: 5.9;basal ganglia: 13.7;cerebral cortex: 14.7;hippocampal formation: 12.3;olfactory bulb: 15.9" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "unprognostic (4.76e-2)" "unprognostic (2.60e-3)" "unprognostic (2.21e-3)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.50e-2)" "unprognostic (9.68e-3)" "unprognostic (3.12e-1)" "unprognostic (8.96e-2)" "unprognostic (2.07e-1)" "unprognostic (3.15e-3)" "unprognostic (1.28e-3)" "unprognostic (1.05e-1)" "unprognostic (5.41e-2)" 0.1 0.2 10.5 0.0 18.9 0.0 0.0 0.0 28.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 0.6 33.3 21.9 3.5 0.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.1 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.4 0.8 0.0 0.3 0.1 0.0 1.7 0.0 0.1 0.0 0.0 11.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 18.9 0.0 28.9 21.9 3.5 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 11.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 3.7 0.0 6.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 73.2;Fibroblasts: 54.7;Intestinal goblet cells: 70.6;Proximal enterocytes: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 267.0;BJ: 180.5;BJ hTERT+: 182.0;fHDF/TERT166: 289.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 4: Stomach - Digestion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA043477: AB_10962952, HPA076405: AB_2686797" "unprognostic (1.76e-1)" "unprognostic (3.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (2.05e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-1)" "unprognostic (1.23e-1)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.05e-10)" "unprognostic (1.66e-1)" "unprognostic (1.46e-1)" "unprognostic (8.24e-2)" "unprognostic (2.07e-2)" 13.4 4.4 0.9 7.6 1.3 2.0 12.2 2.9 2.1 31.1 8.7 18.1 15.4 7.5 29.5 4.8 7.4 19.6 15.7 1.3 0.9 8.5 12.6 10.3 3.2 1.5 1.7 3.5 15.9 12.1 14.2 16.0 1.1 19.7 22.5 3.1 34.4 10.9 2.1 4.1 18.5 15.5 1.3 2.5 35.0 3.9 1.1 1.7 6.3 3.7 7.2 12.5 4.4 1.5 35.8 11.1 8.7 37.2 142.7 267.0 6.4 180.5 182.0 42.7 105.3 22.1 45.1 0.3 38.2 289.3 15.2 5.1 8.9 10.7 51.0 0.4 21.8 2.5 8.7 55.2 62.9 0.4 24.1 99.9 8.0 53.9 5.7 60.1 52.4 0.3 9.0 0.1 70.7 56.8 0.1 1.3 2.1 150.2 33.2 0.2 2.4 11.8 51.5 4.8 0.7 4.6 46.7 2.7 22.9 3.6 13.3 2.4 41.5 45.8 29.0 160.3 18.0 1.7 0.6 0.2 73.5 0.1 65.0 0.0 0.0 0.0 0.2 0.0 0.8 0.3 0.2 0.1 0.0 0.1 0.2 0.2 0.2 0.0 0.0 1.6 0.2 0.1 0.9 1.3 2.9 2.1 1.3 0.9 1.5 1.7 1.1 1.3 1.1 1.5 14.5 0.0 4.8 0.3 4.5 7.6 5.7 7.5 1.2 1.3 10.0 4.2 2.5 8.6 10.0 14.7 2.1 5.1 0.3 9.1 7.9 19.0 0.2 8.0 19.4 10.2 4.9 0.8 0.7 31.6 73.2 54.7 24.5 11.0 1.3 6.9 14.6 5.3 4.7 0.0 0.5 70.6 0.0 0.9 14.5 0.6 32.6 1.1 16.0 1.9 1.0 6.3 0.0 0.0 0.4 31.5 4.9 16.1 12.8 16.3 40.1 0.8 9.2 1.4 0.0 1.7 20.5 0.5 2.4 1.6 7.1 8.2 2.3 4.2 11.1 7.8 DDX17 P72 ENSG00000100201 "DEAD-box helicase 17" Q92841 22 38483438-38507660 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, mRNA processing, mRNA splicing, RNA-mediated gene silencing, rRNA processing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024908, HPA063142" Supported Supported "Nuclear speckles" "Intracellular and membrane" NA NA 420000 "Cluster 1: Neutrophils - Mixed function" "Cluster 51: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "CAB024908: , HPA063142: AB_2684949" "unprognostic (1.46e-2)" "unprognostic (5.99e-3)" "unprognostic (4.24e-3)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-2)" "unprognostic (1.36e-2)" "prognostic favorable (6.06e-4)" "unprognostic (1.17e-1)" "unprognostic (5.51e-1)" "unprognostic (2.52e-2)" "unprognostic (2.73e-2)" "unprognostic (1.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" 181.2 172.4 142.0 124.3 160.1 74.5 198.5 150.9 178.4 248.7 174.8 233.8 107.8 216.1 255.3 150.4 248.1 121.1 168.7 143.5 152.1 247.2 152.8 202.2 186.4 152.8 149.4 298.8 214.0 144.7 309.9 158.8 155.3 234.4 114.2 342.0 188.4 123.3 184.8 197.0 227.2 119.7 146.8 293.0 192.1 91.1 148.2 215.2 300.0 106.6 158.2 204.4 201.5 196.5 122.0 79.9 237.6 141.8 148.2 166.0 120.7 104.3 85.9 118.3 121.2 89.0 100.5 225.8 65.8 119.5 82.9 133.2 212.5 127.9 145.9 202.5 142.1 140.4 175.8 133.5 153.4 192.9 170.8 122.3 183.7 86.8 142.9 211.7 153.3 109.6 139.7 255.3 116.0 75.6 128.7 164.0 148.0 172.1 51.6 218.0 122.9 137.1 141.2 132.6 134.1 75.3 155.0 125.9 161.2 180.5 110.0 148.4 140.8 125.7 77.6 80.0 79.3 203.7 130.3 183.4 156.7 123.1 154.2 6.7 8.1 9.5 7.6 7.9 8.9 9.0 7.1 7.3 7.0 7.2 5.7 6.8 16.6 5.1 8.7 10.5 9.1 6.0 142.0 160.1 150.9 178.4 143.5 152.1 152.8 149.4 155.3 146.8 148.2 196.5 252.6 214.7 325.5 483.8 241.9 223.6 206.1 129.3 158.2 448.3 300.7 195.3 147.2 180.1 223.5 283.3 352.3 127.6 297.5 172.8 33.2 111.7 44.4 280.0 293.4 250.4 236.1 177.1 198.9 90.2 99.9 207.5 216.1 234.2 200.7 505.3 233.8 205.3 113.9 321.4 242.1 191.6 146.5 200.6 194.8 49.1 323.7 197.7 154.7 253.9 235.1 223.4 304.9 334.3 553.3 104.7 153.1 278.7 213.1 193.5 154.8 89.8 270.8 559.4 289.3 260.5 213.6 136.4 74.2 120.4 279.9 139.4 218.6 293.7 147.0 255.3 DMC1 LIM15 ENSG00000100206 "DNA meiotic recombinase 1" Q14565 22 38518948-38570204 "Predicted intracellular proteins" "Cell cycle, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.3" "Group enriched" "Detected in many" 5 "Spermatocytes: 109.3;Spermatogonia: 36.0" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 25.5;hTEC/SVTERT24-B: 17.4;U-266/84: 21.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA001232, CAB015397" Enhanced Approved Nucleoplasm NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB015397: AB_629406, HPA001232: AB_1078683" "unprognostic (1.29e-2)" "unprognostic (3.11e-3)" "unprognostic (4.48e-3)" "unprognostic (5.71e-2)" "unprognostic (6.43e-2)" "unprognostic (2.22e-1)" "unprognostic (8.22e-2)" "unprognostic (2.61e-2)" "unprognostic (4.23e-2)" "unprognostic (3.99e-3)" "unprognostic (7.40e-3)" "unprognostic (1.00e-2)" "unprognostic (2.16e-4)" "unprognostic (3.94e-1)" "unprognostic (2.79e-1)" "unprognostic (7.27e-2)" "unprognostic (2.99e-1)" 0.7 0.2 0.4 1.3 0.4 2.3 0.9 1.2 0.7 1.0 0.4 0.9 0.2 2.5 0.9 0.9 0.8 0.4 2.3 0.4 0.2 0.5 0.3 0.4 2.8 0.5 0.2 1.2 0.5 0.3 0.4 0.7 0.5 1.2 1.1 0.8 0.3 0.7 1.3 1.6 0.7 0.7 0.1 0.5 0.6 12.3 0.1 3.4 0.3 0.5 3.1 0.6 0.7 0.5 7.1 2.6 5.0 0.1 0.4 2.1 0.2 7.4 1.0 11.7 8.1 0.2 0.8 3.5 0.3 2.0 0.0 1.2 2.0 0.3 13.1 25.5 0.5 13.6 2.0 0.2 0.2 1.2 2.7 0.5 0.0 17.4 0.0 0.1 0.9 11.2 10.5 3.5 4.1 3.9 2.8 10.3 9.0 3.5 0.2 6.2 0.0 5.2 1.5 0.9 9.7 0.5 12.5 1.1 0.1 1.1 2.1 2.9 0.3 0.1 0.8 0.1 0.1 9.8 21.4 6.4 2.0 2.8 0.9 0.4 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.4 0.5 0.1 0.1 0.1 0.1 0.4 0.4 1.2 0.7 0.4 0.2 0.5 0.2 0.5 0.1 0.1 0.5 0.6 0.0 2.3 3.6 0.7 2.3 1.0 0.4 1.8 0.7 2.7 2.4 2.5 0.0 2.7 3.7 0.0 1.9 0.4 1.3 1.9 0.2 2.9 0.9 0.8 0.8 0.0 11.8 1.1 0.0 1.7 1.4 0.0 1.3 1.3 1.1 0.4 0.1 1.0 0.0 1.4 1.6 0.0 0.0 1.2 3.0 1.5 1.1 0.0 1.9 0.1 4.8 1.0 2.5 0.6 0.1 0.5 1.5 3.8 0.2 0.1 0.4 0.9 0.2 13.1 1.3 0.9 109.3 36.0 0.3 0.6 0.8 0.9 0.3 2.5 0.5 FAM227A ENSG00000184949 "Family with sequence similarity 227 member A" F5H4B4 22 38578120-38656629 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6;Early spermatids: 87.3;Endometrial ciliated cells: 72.4;Late spermatids: 57.0;Respiratory ciliated cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 10.4;Karpas-707: 17.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003077 Uncertain Uncertain Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA003077: AB_1079264" "unprognostic (7.52e-2)" "unprognostic (3.06e-2)" "unprognostic (1.63e-1)" "unprognostic (8.14e-2)" "unprognostic (5.85e-2)" "unprognostic (2.91e-3)" "unprognostic (4.79e-5)" "unprognostic (5.91e-2)" "unprognostic (3.04e-2)" "unprognostic (4.04e-2)" "unprognostic (1.85e-2)" "unprognostic (4.62e-2)" "unprognostic (6.46e-6)" "unprognostic (3.74e-1)" "unprognostic (3.47e-2)" "unprognostic (2.65e-3)" "unprognostic (1.35e-2)" 0.1 0.6 1.3 0.2 1.2 0.5 0.8 0.9 1.2 1.2 7.5 0.4 0.2 0.7 1.9 0.1 3.8 0.3 0.3 1.5 1.4 1.1 0.1 1.1 0.2 2.5 3.1 0.7 0.4 0.6 4.3 0.1 1.5 0.6 0.2 3.5 0.4 0.4 0.1 0.8 0.1 0.3 1.4 0.1 0.3 4.1 1.4 0.2 1.3 0.0 0.1 0.3 0.3 0.9 0.4 0.9 1.4 1.7 0.4 1.0 0.3 0.2 0.2 0.3 0.2 0.1 0.9 0.1 0.4 0.2 0.4 0.9 0.5 0.2 0.4 10.4 0.9 0.1 2.9 0.2 0.2 0.4 0.4 0.5 0.6 1.0 0.4 1.5 0.2 1.6 0.4 17.3 0.1 0.5 0.4 0.5 0.7 0.2 0.5 1.0 0.1 0.6 0.9 0.3 2.0 0.5 1.4 0.1 0.2 0.5 1.1 0.1 0.3 0.4 0.4 0.4 0.1 1.8 0.8 0.1 0.6 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 1.3 1.2 0.9 1.2 1.5 1.4 2.5 3.1 1.5 1.4 1.4 0.9 0.3 3.2 2.6 20.9 0.0 2.4 3.2 3.7 0.0 6.8 4.1 3.8 2.1 2.8 9.0 5.5 39.6 0.3 0.2 0.3 0.0 3.8 87.3 72.4 5.9 1.6 4.8 0.8 15.5 2.5 0.3 2.6 0.0 4.1 0.0 8.5 0.4 0.3 0.2 5.0 11.1 0.7 4.1 0.6 1.2 57.0 2.1 0.6 0.0 2.8 0.3 9.5 1.0 1.5 2.3 2.3 0.2 1.2 0.1 2.1 0.0 1.4 115.2 30.4 0.0 4.6 2.8 16.4 12.9 0.0 3.4 0.1 1.4 9.5 1.2 1.7 CBY1 "C22orf2, Cby, Chibby, Chibby1, PGEA1, PIGEA-14, PIGEA14" ENSG00000100211 "Chibby family member 1, beta catenin antagonist" Q9Y3M2 22 38656636-38673854 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 106.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.06e-1)" "unprognostic (4.60e-3)" "unprognostic (2.42e-1)" "prognostic favorable (5.22e-5)" "unprognostic (3.46e-2)" "unprognostic (1.74e-1)" "unprognostic (4.29e-2)" "unprognostic (4.51e-2)" "unprognostic (9.36e-2)" "unprognostic (9.33e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (2.16e-1)" "unprognostic (4.71e-2)" "unprognostic (1.85e-1)" "unprognostic (1.35e-2)" 25.9 46.3 38.6 11.7 39.5 6.3 29.3 40.0 42.5 36.5 40.8 51.7 16.9 32.9 51.5 27.3 59.3 19.6 53.2 38.8 38.4 38.6 28.4 23.5 12.1 38.9 40.4 40.4 34.8 34.2 33.5 29.2 38.1 39.9 27.8 20.0 29.5 43.7 25.9 27.3 22.2 38.3 38.7 22.9 31.9 25.2 40.0 14.2 32.2 33.5 15.1 37.0 29.7 39.9 31.2 27.8 40.3 56.9 76.4 46.3 19.6 34.3 39.0 34.1 34.6 17.4 28.1 4.3 30.1 39.4 31.1 28.5 32.1 66.7 46.3 13.2 30.0 3.5 22.8 35.2 51.9 10.5 4.6 43.9 52.6 48.8 65.5 62.3 56.1 13.1 19.5 10.6 37.8 51.0 7.2 14.9 22.4 75.7 34.0 6.6 22.9 9.9 88.7 28.1 47.2 12.5 47.2 21.1 43.5 44.6 19.9 9.8 39.3 19.4 24.7 21.8 14.4 11.4 7.4 4.7 28.9 12.3 23.0 4.5 6.3 6.4 10.6 5.0 14.6 6.9 13.4 12.7 6.7 12.0 19.3 13.7 6.3 8.3 6.3 10.6 5.8 6.4 38.6 39.5 40.0 42.5 38.8 38.4 38.9 40.4 38.1 38.7 40.0 39.9 21.9 12.8 18.5 9.4 5.1 13.8 17.8 57.4 15.9 8.5 32.7 41.0 36.6 28.6 28.9 27.6 6.2 86.1 4.2 13.5 35.2 36.0 60.7 106.3 30.3 24.0 21.6 10.8 12.9 19.5 41.9 34.1 10.2 25.6 8.2 33.6 22.5 10.6 20.1 8.4 13.9 22.0 40.7 6.7 10.4 12.4 49.7 4.2 21.4 5.6 5.5 28.4 2.1 3.5 9.2 24.6 13.2 65.8 5.4 19.9 16.8 51.4 89.0 13.7 26.3 22.8 30.6 20.2 20.2 20.1 16.3 49.5 5.8 84.1 29.4 15.1 TOMM22 TOM22 ENSG00000100216 "Translocase of outer mitochondrial membrane 22" Q9NS69 22 38681957-38685421 "Predicted membrane proteins" "Protein transport, Translocation, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003037 Supported Enhanced Mitochondria NA NA 230000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA003037: AB_1080329" "unprognostic (5.54e-2)" "unprognostic (5.04e-3)" "unprognostic (2.74e-3)" "unprognostic (1.48e-2)" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (2.90e-5)" "unprognostic (1.01e-1)" "unprognostic (4.28e-1)" "unprognostic (7.01e-2)" "unprognostic (1.64e-2)" "unprognostic (7.39e-2)" "unprognostic (5.44e-2)" "unprognostic (5.32e-2)" "unprognostic (1.99e-1)" "unprognostic (7.86e-2)" "unprognostic (1.64e-1)" 19.6 21.1 27.6 19.0 28.5 30.4 17.2 29.0 29.7 16.6 29.4 22.6 24.5 15.5 19.2 28.4 20.5 11.5 29.1 27.7 28.7 23.9 28.5 12.7 25.3 28.6 28.2 19.1 21.1 22.5 9.9 15.7 28.9 15.1 27.6 8.6 21.4 12.5 34.6 22.1 19.4 19.4 28.0 17.0 20.3 17.0 29.6 27.0 17.1 31.0 30.5 23.8 17.8 28.3 61.7 35.5 53.4 56.9 38.6 35.7 57.5 49.7 34.3 71.1 53.1 65.0 35.8 62.0 39.9 48.9 48.7 49.7 81.8 75.2 56.7 53.8 89.9 83.4 25.2 63.0 50.2 223.2 56.7 49.0 52.6 64.1 41.6 37.0 52.9 59.5 64.4 48.2 48.1 47.9 67.7 103.3 82.0 80.8 71.5 73.9 69.2 58.8 47.7 44.3 62.4 41.3 58.1 72.7 59.1 36.1 50.5 73.1 54.3 43.4 81.8 40.1 76.2 65.9 85.7 94.3 54.3 76.0 60.6 12.9 50.9 16.6 35.4 51.1 44.9 48.7 37.8 37.5 66.4 37.8 38.0 41.4 5.0 42.7 43.1 58.0 48.7 72.8 27.6 28.5 29.0 29.7 27.7 28.7 28.6 28.2 28.9 28.0 29.6 28.3 62.4 25.6 30.4 4.2 123.3 167.0 134.8 158.7 109.8 30.1 79.5 67.7 70.2 82.9 68.0 71.7 16.7 180.0 89.7 74.8 223.0 135.3 139.6 50.5 58.8 77.1 105.1 98.8 7.3 133.2 232.1 70.4 65.7 50.6 74.3 100.3 69.9 101.4 163.9 28.6 8.4 133.5 99.7 120.2 130.7 143.2 55.3 93.3 113.8 4.7 153.2 76.1 105.0 4.5 8.7 116.2 85.2 54.5 130.3 153.4 116.2 245.9 35.2 33.7 72.3 73.3 76.9 130.1 148.2 185.5 210.3 135.6 102.6 100.9 189.7 158.7 JOSD1 KIAA0063 ENSG00000100221 "Josephin domain containing 1" Q15040 22 38685543-38701556 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001168 Uncertain NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "HPA001168: AB_1079162" "unprognostic (6.50e-2)" "unprognostic (1.06e-2)" "unprognostic (3.42e-3)" "unprognostic (5.67e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.50e-4)" "unprognostic (1.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-3)" "unprognostic (2.46e-1)" "unprognostic (1.83e-3)" "unprognostic (1.06e-1)" "unprognostic (4.41e-1)" "unprognostic (2.88e-2)" "unprognostic (4.41e-1)" 33.6 22.1 30.7 25.0 32.6 89.6 25.0 30.9 34.2 24.0 23.2 40.9 27.5 25.6 14.8 23.0 28.0 34.1 24.6 33.0 27.7 20.0 23.8 30.9 21.8 29.9 28.7 48.9 25.9 16.8 27.8 22.7 30.6 23.1 38.4 21.5 21.3 18.2 24.4 27.4 35.8 27.8 29.2 22.7 24.8 19.2 29.2 27.9 22.3 22.0 24.3 33.1 22.9 32.6 69.6 24.5 35.1 45.7 44.1 53.5 26.6 52.2 62.1 66.5 69.3 40.5 34.4 66.3 26.4 52.6 44.3 43.8 49.2 46.4 53.4 71.4 32.6 35.2 57.3 34.9 74.9 63.8 33.1 46.7 67.8 62.9 107.1 58.3 79.8 41.0 32.0 68.2 49.4 29.4 27.9 25.9 13.3 41.8 27.5 49.5 51.5 27.9 36.1 35.3 32.3 17.4 59.9 29.3 54.7 29.2 29.4 18.2 70.0 39.4 48.1 51.4 32.1 74.9 71.1 54.2 52.4 33.5 37.5 1.0 1.8 1.9 2.6 2.8 1.8 1.6 2.2 3.4 1.3 1.6 2.3 3.7 3.6 2.3 1.6 1.0 3.2 1.4 30.7 32.6 30.9 34.2 33.0 27.7 29.9 28.7 30.6 29.2 29.2 32.6 45.0 25.6 17.1 12.7 53.1 46.4 75.0 20.2 34.7 28.2 41.0 45.1 17.0 44.3 18.5 36.8 22.9 10.5 94.1 133.1 13.7 34.6 4.9 51.6 38.6 35.3 23.4 21.0 25.2 39.3 15.0 24.2 53.5 114.5 16.5 26.9 23.9 24.8 22.7 18.5 21.7 61.8 12.2 32.6 106.3 4.8 12.8 74.2 16.0 6.5 27.3 27.5 12.3 7.1 24.6 68.0 88.1 13.9 61.5 62.4 64.6 18.1 17.4 23.6 13.1 27.9 27.3 16.2 24.2 35.5 51.6 12.9 75.2 17.8 35.0 102.7 GTPBP1 "GP-1, HSPC018" ENSG00000100226 "GTP binding protein 1" O00178 22 38705742-38738299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 105.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003166, HPA064702" Approved Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 64000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Cytosol" "Nuclear bodies" "HPA003166: AB_10601476, HPA064702: AB_2685329" "unprognostic (1.42e-3)" "unprognostic (5.82e-3)" "unprognostic (1.08e-1)" "unprognostic (1.18e-2)" "unprognostic (1.94e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (3.17e-1)" "unprognostic (3.67e-2)" "unprognostic (1.56e-2)" "unprognostic (2.95e-2)" "unprognostic (2.88e-1)" "unprognostic (5.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.76e-2)" "unprognostic (3.40e-1)" "unprognostic (1.98e-3)" 18.4 19.0 16.5 23.4 19.1 105.4 18.4 20.0 44.3 20.3 20.8 20.5 20.5 20.0 12.1 22.4 22.1 17.7 20.0 18.4 19.3 18.4 17.1 28.9 23.0 19.3 17.0 27.4 22.0 19.2 25.5 16.0 17.0 23.8 17.6 34.7 21.2 15.5 31.7 27.5 22.9 16.6 15.5 28.0 20.4 20.3 16.7 20.0 24.9 19.9 23.0 18.7 19.4 23.9 29.2 10.5 37.4 30.2 12.6 19.7 18.3 27.4 28.7 39.0 33.9 22.0 16.3 27.9 9.8 26.9 17.5 26.6 45.5 28.8 21.6 49.2 32.8 48.7 36.9 16.3 23.9 57.7 24.3 20.3 22.0 31.2 48.7 21.3 24.3 20.2 29.4 56.5 21.8 12.1 32.1 26.1 27.0 16.7 20.8 61.8 38.2 36.7 13.8 23.3 51.0 17.7 33.3 21.0 19.6 16.2 19.0 24.2 26.1 22.3 22.0 16.4 21.2 51.8 18.7 38.5 20.1 29.0 16.9 3.5 3.1 3.9 4.7 4.6 4.2 4.6 3.5 4.9 3.4 3.8 2.5 3.7 7.8 2.3 5.1 1.7 3.3 3.4 16.5 19.1 20.0 44.3 18.4 19.3 19.3 17.0 17.0 15.5 16.7 23.9 17.8 9.6 8.4 7.8 31.8 27.8 36.0 12.7 15.4 32.6 17.5 15.5 11.2 5.7 12.4 12.9 22.9 7.2 35.9 40.3 5.9 13.2 4.5 22.2 14.3 13.1 16.2 35.3 5.5 19.3 7.9 14.5 23.4 26.4 14.0 17.5 13.6 12.4 8.6 20.2 7.9 24.3 16.2 18.4 43.9 5.4 16.1 19.3 10.6 4.7 26.6 13.2 20.6 5.5 15.2 19.9 21.1 19.2 52.8 47.4 29.8 6.1 16.6 41.0 26.3 19.9 14.5 17.2 7.7 19.2 34.2 19.0 31.9 15.5 13.0 51.0 SUN2 UNC84B ENSG00000100242 "Sad1 and UNC84 domain containing 2" Q9UH99 22 38734725-38794143 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001209 Supported Supported "Nuclear membrane" NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane" "HPA001209: AB_1080465" "unprognostic (9.76e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" "unprognostic (5.09e-2)" "unprognostic (1.36e-1)" "unprognostic (5.57e-2)" "unprognostic (1.94e-2)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" "unprognostic (1.25e-3)" "unprognostic (8.15e-2)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (8.10e-2)" "unprognostic (2.33e-2)" 137.8 35.1 123.6 73.6 219.0 160.4 111.7 149.1 155.3 95.4 41.4 107.8 47.6 128.2 22.2 84.0 125.3 41.1 86.7 118.3 133.1 52.8 121.9 107.0 104.0 187.1 182.2 112.9 78.0 18.2 40.3 28.7 170.7 78.2 25.2 12.3 74.9 52.1 145.4 90.3 93.1 46.1 107.2 97.2 94.3 34.6 163.3 74.3 53.1 63.8 60.0 121.7 89.0 257.7 89.8 41.0 40.0 44.7 118.8 29.5 52.0 60.2 69.4 69.7 58.9 36.8 98.7 28.1 71.9 85.9 43.1 65.4 13.4 44.7 28.4 98.0 54.7 18.4 44.7 33.7 71.9 62.3 184.0 25.0 37.3 33.6 31.2 46.9 56.2 55.3 23.5 154.3 38.5 28.7 35.0 53.9 3.9 63.0 26.2 57.6 55.8 85.7 17.4 43.1 35.3 13.2 67.0 73.7 35.1 18.5 49.5 115.3 95.2 50.6 43.3 44.9 79.5 113.1 38.2 30.4 93.8 74.2 86.6 29.0 13.7 18.6 42.3 15.6 27.5 10.8 27.0 34.9 10.7 10.1 27.6 33.6 13.9 24.8 26.9 6.7 19.9 24.8 123.6 219.0 149.1 155.3 118.3 133.1 187.1 182.2 170.7 107.2 163.3 257.7 55.5 22.4 22.9 20.2 57.0 18.1 28.4 15.1 24.5 9.9 36.5 39.0 6.2 40.0 17.8 33.1 8.4 16.9 141.8 65.6 3.9 34.9 1.8 11.6 15.8 37.4 18.6 31.8 12.5 47.6 65.9 34.0 42.8 32.9 25.4 41.5 52.1 109.6 25.0 21.9 7.7 30.1 8.2 42.4 21.4 4.4 61.2 41.8 17.8 16.9 25.5 21.4 201.8 7.1 132.9 60.0 41.8 65.5 44.7 22.0 42.2 18.9 5.7 13.0 52.6 100.7 37.0 3.8 1.1 32.1 17.2 14.8 133.4 10.9 21.4 21.4 DNAL4 "dJ327J16, PIG27" ENSG00000100246 "Dynein axonemal light chain 4" O96015 22 38778508-38794198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 124.1;Late spermatids: 210.7;Spermatocytes: 77.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 64.0" "Low region specificity" "Detected in all" HPA003647 Approved Approved Nucleoplasm,Nucleoli,Centrosome,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome "Nucleoplasm, Nucleoli, Cytosol" "HPA003647: AB_1078712" "unprognostic (8.45e-2)" "unprognostic (8.15e-3)" "unprognostic (2.35e-1)" "unprognostic (3.14e-3)" "unprognostic (3.74e-1)" "unprognostic (1.52e-1)" "unprognostic (6.46e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.06e-1)" "unprognostic (2.07e-1)" "prognostic favorable (1.20e-6)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (8.00e-2)" "unprognostic (4.83e-2)" 11.3 18.0 29.1 6.7 32.3 4.4 14.5 21.0 36.5 18.3 23.2 12.9 7.9 12.2 15.0 18.9 35.4 12.9 13.7 29.2 28.3 24.4 11.1 13.9 8.1 22.1 23.3 17.5 21.3 31.1 30.9 9.9 22.1 18.3 9.6 13.8 18.1 12.1 7.0 17.5 9.8 7.5 22.0 11.4 16.4 65.5 28.0 14.3 25.4 6.2 8.3 14.2 15.5 24.5 17.9 8.9 17.5 15.5 21.8 21.7 0.0 7.5 14.0 11.4 12.2 5.7 20.1 4.5 15.7 10.7 13.1 8.3 11.0 20.5 7.7 11.4 14.8 2.6 2.5 6.6 34.9 14.5 3.7 17.1 64.0 14.9 26.8 29.7 16.6 22.1 5.3 8.5 13.8 21.9 13.6 14.0 6.8 26.3 7.4 12.8 7.5 5.9 23.7 10.8 24.3 13.5 15.4 11.5 30.7 12.1 20.7 13.7 9.8 10.1 10.1 15.5 7.5 5.3 1.8 2.1 29.9 4.9 9.8 15.0 8.5 11.9 11.2 8.9 13.8 7.1 9.3 10.2 8.7 10.6 10.5 9.0 15.0 16.2 11.3 13.2 9.3 7.5 29.1 32.3 21.0 36.5 29.2 28.3 22.1 23.3 22.1 22.0 28.0 24.5 8.2 6.4 10.5 5.5 5.1 5.6 13.4 18.9 10.2 15.0 20.6 17.8 4.3 14.3 15.2 3.7 2.1 27.6 9.7 10.9 31.3 28.4 124.1 56.4 11.8 8.5 12.6 11.2 11.0 15.5 21.2 10.1 6.1 10.5 15.2 20.3 12.8 3.8 13.7 11.8 10.6 14.7 14.2 4.4 2.8 210.7 11.8 6.5 8.8 4.7 5.7 18.9 8.2 6.6 5.1 18.4 9.1 7.5 1.3 9.8 8.5 20.0 41.0 15.4 6.6 6.6 11.6 77.7 20.0 9.1 10.5 19.8 6.0 20.1 13.2 12.0 NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 280.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Excitatory neurons: 41.7;Inhibitory neurons: 50.4;Oligodendrocyte precursor cells: 19.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 23.3;SCLC-21H: 30.8;SiHa: 23.6;U-87 MG: 87.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 420000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" 2.7 5.0 91.6 1.9 75.4 0.3 2.8 0.3 145.7 8.7 0.0 9.5 1.3 10.9 3.8 3.0 7.9 2.0 15.7 280.2 17.0 1.6 1.9 1.9 1.6 4.1 15.2 8.1 5.2 7.0 6.8 0.4 0.7 8.1 1.5 5.3 4.8 7.0 0.6 1.1 3.3 7.6 3.1 2.5 5.0 1.8 58.0 0.7 2.7 2.5 1.5 7.3 4.8 46.0 1.0 6.2 0.2 1.8 12.2 1.2 0.0 4.1 0.9 7.9 2.7 6.2 1.3 0.0 7.2 1.1 23.3 0.8 1.7 0.2 2.6 0.6 2.0 0.0 0.2 9.6 1.2 0.1 0.3 3.9 0.4 7.2 0.1 11.4 0.3 0.1 7.7 0.3 0.3 9.7 0.0 0.5 7.3 3.0 2.2 1.6 0.0 15.3 2.0 17.1 30.8 2.0 23.6 0.1 0.7 1.7 9.9 2.5 0.4 14.1 8.4 0.0 0.7 2.1 0.0 0.0 87.9 18.5 7.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 91.6 75.4 0.3 145.7 280.2 17.0 4.1 15.2 0.7 3.1 58.0 46.0 4.7 0.0 0.0 9.4 0.3 1.1 2.7 0.9 0.0 6.6 3.3 1.5 18.0 4.3 3.0 3.7 2.1 0.0 2.3 0.0 0.0 7.3 1.7 1.7 3.2 4.2 1.8 0.0 41.7 3.8 0.0 1.5 0.5 3.0 0.0 1.5 5.0 0.4 0.2 0.0 50.4 0.2 6.1 0.3 0.9 0.8 1.8 0.3 1.8 1.9 0.0 4.8 6.2 19.1 10.5 2.0 0.0 2.2 0.9 3.8 0.1 0.5 2.2 3.3 0.0 2.4 2.8 0.2 1.3 0.1 1.0 0.0 1.7 0.3 0.0 3.4 CBX6 ENSG00000183741 "Chromobox 6" O95503 22 38861422-38872249 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048653 Uncertain Approved Nucleoplasm,Mitochondria NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Mitochondria" "HPA048653: AB_2680479" "unprognostic (1.65e-2)" "unprognostic (8.66e-2)" "unprognostic (6.20e-3)" "unprognostic (3.14e-3)" "unprognostic (1.56e-1)" "unprognostic (2.62e-1)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.90e-2)" "unprognostic (3.72e-3)" "unprognostic (5.97e-2)" "prognostic favorable (2.46e-6)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.39e-2)" "unprognostic (1.03e-1)" "unprognostic (1.94e-1)" "unprognostic (2.26e-2)" 16.3 22.4 67.1 16.5 53.6 28.3 12.3 9.9 83.6 21.0 0.0 39.3 6.5 34.0 14.5 13.3 27.0 11.3 17.7 88.2 10.1 18.7 6.3 17.2 14.2 16.6 14.0 24.4 17.1 49.5 27.5 4.3 10.0 22.0 7.2 8.5 13.7 25.9 8.9 8.2 17.1 26.1 5.5 15.9 20.5 4.3 21.8 12.5 19.0 6.7 15.3 31.0 11.9 30.8 40.3 41.7 9.1 31.3 68.5 38.2 2.8 42.8 24.5 21.8 20.3 21.1 36.5 65.3 31.2 29.5 15.3 46.8 17.0 18.3 11.9 63.1 53.0 6.7 18.5 7.4 37.2 32.6 31.1 57.0 9.1 49.7 23.5 30.1 24.9 18.4 14.9 32.2 15.1 45.5 20.2 9.5 8.1 23.1 31.9 29.9 30.5 25.9 31.3 37.4 44.3 9.8 27.5 36.4 23.7 3.2 25.0 19.3 32.7 18.9 57.9 33.2 29.6 32.9 34.1 23.5 37.0 33.6 40.1 2.2 9.1 4.7 18.6 12.4 15.3 6.7 12.6 13.1 9.1 7.7 10.3 12.6 4.0 9.1 12.5 46.1 8.0 20.0 67.1 53.6 9.9 83.6 88.2 10.1 16.6 14.0 10.0 5.5 21.8 30.8 30.5 16.0 14.7 9.8 25.1 33.9 47.4 18.4 16.5 100.4 42.6 31.6 27.5 52.9 22.1 73.5 39.6 12.4 83.0 9.6 35.2 102.6 1.1 6.9 46.0 36.4 122.7 17.7 28.9 50.1 2.0 48.5 3.1 17.5 6.3 18.7 46.8 32.4 19.8 124.5 27.3 3.2 30.5 40.8 121.1 2.9 74.3 33.2 81.8 14.0 91.1 91.2 57.7 15.1 23.3 46.9 9.1 80.9 24.5 58.9 0.1 51.7 18.0 59.4 72.3 54.4 85.1 4.2 6.8 10.4 34.0 4.7 35.8 40.9 0.9 82.6 APOBEC3A "ARP3, PHRBN" ENSG00000128383 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3A" P31941 22 38952741-38992778 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 93.9;lymphoid tissue: 48.3;urinary bladder: 24.4" "Cell type enriched" "Detected in many" 4 "Urothelial cells: 426.0" "Group enriched" "Detected in many" 4 "cervical cancer: 11.3;head and neck cancer: 15.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 1014.5" "Lineage enriched" "Detected in many" 8 "monocytes: 1014.5" "Not detected" "Not detected" "HPA043237, HPA056980, HPA066719" Approved Uncertain Nucleoplasm NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA043237: AB_10795980, HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (6.45e-3)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (5.21e-3)" "unprognostic (1.31e-1)" "unprognostic (2.72e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-1)" "unprognostic (3.52e-1)" "unprognostic (2.59e-3)" "unprognostic (9.01e-3)" "unprognostic (2.00e-1)" "unprognostic (1.13e-2)" "unprognostic (1.76e-1)" "unprognostic (4.98e-2)" "unprognostic (3.41e-1)" "unprognostic (1.91e-1)" 7.9 0.4 0.5 20.9 0.5 93.9 0.8 0.7 1.1 2.2 0.8 1.5 1.4 0.4 0.3 12.2 4.2 6.3 1.4 0.9 0.5 0.7 2.0 13.4 1.1 0.6 0.4 0.2 1.5 0.4 0.3 3.5 0.7 0.4 0.6 0.2 6.7 0.3 0.5 0.6 0.8 1.7 0.3 48.3 1.1 0.2 0.5 2.4 1.0 3.7 21.1 24.4 10.3 1.0 0.1 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.3 0.6 0.3 34.7 223.9 8.4 0.7 1014.5 1.5 3.1 0.6 0.7 10.4 0.8 0.7 0.7 121.7 0.9 298.5 1.3 1.0 149.1 0.5 0.5 0.7 1.1 0.9 0.5 0.6 0.4 0.7 0.3 0.5 1.0 0.7 28.9 33.6 0.0 0.5 1.3 16.0 1.8 0.0 0.6 0.7 0.3 0.1 0.0 24.1 1.8 4.2 0.3 0.2 17.5 0.0 0.1 0.6 0.5 0.2 1.4 0.0 8.0 0.0 0.2 0.3 6.3 0.0 0.6 25.9 0.3 0.7 0.4 14.9 0.0 0.0 0.0 2.0 18.8 41.4 0.1 0.3 91.3 16.0 0.0 17.9 0.8 2.1 0.0 0.0 1.3 27.4 0.4 15.6 6.7 4.5 0.2 10.7 0.8 0.0 1.0 1.2 0.1 0.4 48.7 6.8 0.3 3.1 0.2 1.7 426.0 APOBEC3B "FLJ21201, PHRBNL" ENSG00000179750 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3B" Q9UH17 22 38982347-38992804 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.4;intestine: 12.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 11.8;Ductal cells: 14.7;Erythroid cells: 14.1;Plasma cells: 26.2;Urothelial cells: 11.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 256.0;Karpas-707: 283.6" "HPA056980, HPA066719" Approved Nucleoplasm NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm "HPA056980: AB_2683298, HPA066719: AB_2685711" "unprognostic (2.92e-2)" "prognostic favorable (2.58e-5)" "unprognostic (4.29e-2)" "unprognostic (1.19e-1)" "unprognostic (2.50e-1)" "unprognostic (1.35e-1)" "unprognostic (1.69e-2)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.47e-2)" "unprognostic (2.98e-2)" "unprognostic (2.70e-1)" "unprognostic (1.04e-1)" 0.9 1.2 0.1 5.7 0.1 28.4 2.0 0.1 0.2 1.2 0.1 12.1 7.3 1.0 0.4 3.0 0.7 1.1 0.8 0.1 0.1 2.7 1.1 1.9 5.9 0.1 0.1 0.7 3.3 1.2 0.2 1.6 0.1 0.4 12.0 0.3 2.8 0.2 0.4 2.1 4.3 1.4 0.1 6.4 4.1 0.3 0.2 2.5 1.3 0.2 8.6 7.6 1.5 0.2 256.0 28.0 10.5 68.1 1.5 6.0 18.6 23.0 19.7 43.0 56.5 54.7 46.6 3.0 20.4 22.9 63.0 108.2 1.3 4.5 43.1 92.1 2.5 72.5 5.6 14.0 0.7 61.7 43.0 2.3 0.5 45.1 2.2 8.9 17.0 0.0 41.6 283.6 68.1 6.9 0.2 35.3 0.3 24.6 25.2 1.8 105.0 95.6 9.1 42.2 1.8 0.0 0.0 0.3 16.0 1.8 33.0 18.1 10.2 48.0 81.9 7.5 0.7 62.8 18.0 0.3 34.4 68.2 100.7 0.4 1.0 0.0 0.2 4.9 0.0 7.2 0.5 0.3 0.6 3.1 0.0 0.3 1.4 1.7 1.7 0.0 2.8 3.5 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.0 0.0 1.7 0.0 2.2 5.4 3.2 11.8 0.6 0.0 1.5 0.5 0.3 0.0 8.1 0.0 0.0 1.0 0.4 4.6 0.0 14.7 0.0 5.9 0.6 0.2 0.0 14.1 0.0 1.8 1.8 0.8 3.1 5.3 0.0 0.8 0.4 0.0 2.1 0.0 0.0 0.4 10.2 1.2 6.3 0.0 0.0 2.3 7.2 0.0 1.4 0.0 0.0 0.0 0.0 6.0 9.9 0.0 26.2 1.4 0.4 0.3 9.3 0.0 0.0 0.0 0.9 0.0 0.0 4.2 3.3 0.8 0.5 0.1 1.6 11.4 APOBEC3C "APOBEC1L, ARDC2, ARDC4, ARP5, bK150C2.3, PBI" ENSG00000244509 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3C" Q9NRW3 22 39014257-39020352 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB033048, HPA071523" Approved Approved "Intermediate filaments" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Intermediate filaments" "CAB033048: AB_2057401, HPA071523: AB_2686409" "unprognostic (1.79e-3)" "prognostic favorable (1.08e-5)" "unprognostic (4.32e-3)" "unprognostic (3.20e-3)" "unprognostic (4.68e-2)" "unprognostic (2.13e-1)" "unprognostic (5.18e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-3)" "unprognostic (7.40e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (8.91e-10)" "unprognostic (5.92e-2)" "unprognostic (1.11e-1)" "unprognostic (4.10e-1)" "unprognostic (3.52e-3)" 12.3 36.2 3.1 31.1 3.2 31.4 12.3 3.1 4.0 23.1 3.5 20.2 14.0 22.6 51.7 22.7 56.0 18.4 24.0 3.0 3.5 6.0 7.0 20.6 57.8 5.0 3.6 38.2 5.1 10.5 3.8 11.6 5.1 25.9 33.1 3.4 22.1 36.1 2.7 19.8 17.4 30.8 4.5 36.5 18.1 29.4 3.9 25.2 15.2 11.3 67.8 27.6 17.3 6.5 39.4 38.1 6.3 73.9 40.2 82.6 32.4 28.3 54.9 41.0 54.5 36.8 43.7 115.5 18.6 56.1 26.2 39.4 6.5 120.2 39.5 44.3 32.0 111.8 1.6 30.6 43.5 73.4 107.1 90.5 68.1 54.0 13.3 20.4 23.0 0.9 69.9 142.3 83.0 0.4 29.6 39.8 9.8 0.5 82.8 51.1 16.9 96.6 27.2 51.4 1.9 4.9 40.9 0.2 21.7 15.9 0.2 26.8 11.9 21.8 37.1 11.9 12.4 38.6 42.7 9.5 66.9 47.1 58.8 86.6 104.4 277.0 309.1 220.6 212.6 241.6 164.7 276.9 106.9 249.1 54.0 196.9 14.1 196.9 247.8 86.9 168.9 173.6 3.1 3.2 3.1 4.0 3.0 3.5 5.0 3.6 5.1 4.5 3.9 6.5 3.3 3.2 16.2 0.0 68.8 25.2 45.4 44.1 24.5 0.2 16.4 8.9 23.0 28.6 18.4 7.3 0.0 4.3 60.2 56.6 0.0 31.6 3.2 11.0 16.4 9.6 26.4 57.2 0.0 1.3 1.4 26.5 5.6 15.6 57.0 78.6 30.0 1.2 61.9 0.0 0.0 17.8 28.5 49.0 37.3 9.3 57.8 34.2 44.4 0.0 65.1 24.4 117.4 0.5 0.0 11.5 16.6 38.0 55.4 18.9 3.2 1.3 13.6 0.8 26.3 11.9 20.1 1.5 1.5 9.7 16.3 1.9 67.7 53.5 18.8 41.9 AL022318.4 ENSG00000284554 "Novel protein" 22 39014363-39033276 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "lymphoid tissue: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "Karpas-707: 2.7" HPA055116 Uncertain NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "HPA055116: AB_2682701" 0.1 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.4 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.3 0.1 1.1 0.3 0.3 0.2 0.2 0.0 0.0 0.0 0.4 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.1 2.5 0.4 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 2.5 2.0 1.3 2.8 2.3 3.6 0.1 2.8 1.5 1.5 0.0 0.6 1.8 1.0 2.8 0.0 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.3 0.4 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 APOBEC3D "APOBEC3DE, APOBEC3E, ARP6" ENSG00000243811 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3D" Q96AK3 22 39021113-39033277 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.3" "Cell type enhanced" "Detected in many" "B-cells: 6.7;NK-cells: 9.2;Plasma cells: 6.4;T-cells: 8.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 11.8;Karpas-707: 46.7" HPA055116 Approved NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA055116: AB_2682701" "prognostic favorable (2.51e-5)" "prognostic favorable (1.31e-4)" "unprognostic (2.69e-2)" "prognostic favorable (4.47e-4)" "unprognostic (2.62e-2)" "unprognostic (3.06e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (4.52e-2)" "unprognostic (2.45e-2)" "unprognostic (4.50e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (3.76e-7)" "unprognostic (4.76e-2)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "prognostic favorable (3.01e-4)" 1.7 2.2 1.2 8.6 1.2 2.5 1.8 1.5 1.2 3.5 1.1 3.5 3.8 3.3 3.0 1.7 5.2 4.1 1.2 1.0 0.9 1.6 1.2 3.3 15.3 1.6 1.2 4.1 0.5 1.1 0.9 2.2 1.3 2.6 4.3 0.3 2.8 2.3 0.9 1.4 5.3 2.4 1.3 12.0 5.3 2.4 1.1 7.7 1.9 1.2 13.8 4.6 2.7 1.4 0.5 0.0 0.3 2.1 3.1 5.5 1.9 0.3 3.3 3.9 4.4 0.9 5.3 6.1 0.9 4.4 2.5 0.6 0.3 0.0 1.4 11.1 1.2 10.7 0.1 0.0 8.3 1.5 11.8 3.6 0.5 6.3 0.0 0.0 2.9 9.0 2.7 46.7 0.2 0.0 5.2 3.4 0.8 0.0 0.5 4.3 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.1 1.7 1.4 0.1 0.5 1.1 0.1 1.2 0.6 0.0 3.2 3.9 0.8 1.6 3.3 1.5 4.8 1.3 3.5 8.0 3.5 5.2 6.7 5.8 7.3 0.8 6.8 2.7 3.6 1.7 4.9 6.5 5.4 5.8 3.4 1.2 1.2 1.5 1.2 1.0 0.9 1.6 1.2 1.3 1.3 1.1 1.4 0.9 3.2 0.5 0.0 6.7 1.0 1.5 0.9 0.0 0.2 0.3 0.6 0.4 5.7 1.1 1.8 0.0 1.3 3.8 3.0 0.0 0.2 0.5 1.0 0.8 1.9 1.8 1.7 0.0 0.2 0.7 1.8 2.6 0.6 0.0 1.1 2.5 0.2 2.5 0.0 0.0 3.6 0.0 3.4 1.0 0.0 3.1 1.1 3.6 2.8 1.2 0.3 9.2 0.5 0.0 0.2 0.1 1.9 6.4 1.4 1.3 0.3 2.7 0.5 0.0 0.9 1.4 0.2 0.4 0.2 0.9 0.5 8.7 0.8 2.1 2.6 APOBEC3F "ARP8, BK150C2.4.MRNA, KA6" ENSG00000128394 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3F" Q8IUX4 22 39040604-39055972 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 19.9" HPA073637 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA073637: " "unprognostic (1.38e-3)" "unprognostic (1.28e-3)" "unprognostic (4.63e-2)" "unprognostic (1.63e-2)" "unprognostic (6.16e-2)" "unprognostic (3.51e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" "unprognostic (6.03e-2)" "unprognostic (1.34e-2)" "unprognostic (1.57e-1)" "unprognostic (1.88e-1)" "unprognostic (2.06e-3)" "unprognostic (9.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.49e-1)" "prognostic favorable (8.28e-4)" 2.2 6.3 2.2 9.2 2.1 3.3 2.5 2.2 2.7 4.0 3.4 3.5 3.7 4.1 6.3 2.4 8.3 3.5 5.5 2.0 2.2 3.4 2.9 3.4 15.7 3.1 2.6 8.8 3.0 5.2 3.4 2.2 2.8 4.8 2.8 1.1 4.9 5.2 0.6 1.6 3.8 4.5 2.3 11.9 4.8 8.2 2.5 5.3 3.0 1.3 14.5 4.5 3.2 2.9 4.9 4.2 1.8 6.2 4.9 7.1 2.2 4.2 6.9 8.8 14.0 3.9 9.1 12.9 4.1 8.9 7.7 6.5 1.7 6.0 3.8 11.7 5.3 16.5 0.5 2.5 8.6 3.6 7.0 9.5 3.0 5.0 1.5 5.1 8.5 3.5 1.3 19.9 4.8 3.9 4.0 2.7 0.8 0.5 0.7 6.1 0.7 2.5 8.1 6.6 0.9 1.5 4.7 1.2 2.5 3.5 4.7 1.9 2.3 2.0 5.0 0.4 2.0 3.4 1.7 0.5 5.6 1.9 3.1 3.2 4.7 9.4 8.5 9.1 9.8 27.7 5.6 9.0 6.0 34.2 3.4 5.6 3.1 14.6 14.5 4.6 8.4 7.4 2.2 2.1 2.2 2.7 2.0 2.2 3.1 2.6 2.8 2.3 2.5 2.9 1.6 0.0 0.5 0.0 9.8 0.9 4.9 6.3 2.2 0.0 2.1 2.2 5.9 8.6 4.2 0.0 0.0 2.0 7.6 0.8 1.9 7.4 2.4 4.8 3.8 2.6 1.2 2.1 0.1 3.9 1.4 2.9 2.6 3.6 2.5 11.0 3.6 1.6 5.9 0.0 0.0 2.2 4.1 2.2 1.4 5.2 5.0 2.8 5.4 2.8 5.3 2.2 8.2 0.5 0.0 4.8 3.6 6.4 9.6 4.5 0.5 5.3 4.6 0.2 0.0 1.0 2.6 0.3 0.4 1.6 0.9 1.6 5.4 7.8 1.5 5.9 APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.9" "Cell type enhanced" "Detected in many" "dendritic cells: 145.4;monocytes: 69.1;NK-cells: 251.3;Plasma cells: 69.5;T-cells: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 30.0;Daudi: 38.3;HDLM-2: 31.8;Karpas-707: 44.2" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA001812: AB_1078175, HPA073637: " "prognostic favorable (4.78e-4)" "prognostic favorable (4.70e-4)" "unprognostic (8.18e-3)" "prognostic favorable (6.03e-5)" "unprognostic (2.37e-1)" "unprognostic (3.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.33e-1)" "unprognostic (4.23e-1)" "unprognostic (4.13e-3)" "unprognostic (9.13e-3)" "unprognostic (1.81e-1)" "prognostic unfavorable (8.66e-13)" "unprognostic (3.41e-2)" "unprognostic (5.83e-2)" "unprognostic (2.91e-2)" "prognostic favorable (6.30e-4)" 5.5 8.1 3.3 21.7 3.2 15.9 8.6 3.4 4.6 7.7 2.9 7.6 5.5 10.3 10.4 6.1 21.1 11.1 4.3 3.0 4.0 4.1 5.7 14.5 45.9 3.9 3.7 22.7 1.7 4.8 3.5 5.0 3.9 7.8 9.4 1.4 8.5 22.4 1.2 1.6 9.6 9.6 4.0 28.2 10.0 20.1 3.4 25.9 5.8 2.7 35.1 15.7 6.4 4.5 4.5 0.1 0.0 0.0 5.0 9.7 0.3 1.0 16.8 19.9 30.0 1.6 22.6 38.3 0.5 7.3 11.6 0.1 0.2 1.3 6.0 31.8 0.1 23.1 0.0 0.2 21.8 7.1 10.1 14.3 0.5 10.9 2.4 0.0 2.4 1.2 1.9 44.2 3.1 0.0 7.6 7.7 0.6 0.0 1.7 15.3 0.0 25.8 0.0 19.6 0.0 0.0 0.5 0.0 2.0 1.7 0.0 13.2 0.0 2.8 0.2 0.0 0.0 0.0 3.5 0.5 3.2 6.9 5.0 30.7 42.3 28.7 363.8 98.1 207.6 84.9 108.8 281.7 52.4 66.1 34.3 160.2 34.8 232.2 123.0 28.1 92.3 297.8 3.3 3.2 3.4 4.6 3.0 4.0 3.9 3.7 3.9 4.0 3.4 4.5 8.4 3.2 8.9 1.0 55.7 1.8 15.5 27.0 4.6 0.4 3.0 6.6 3.7 7.2 14.4 0.0 2.1 3.9 145.4 0.6 5.9 11.7 47.2 5.7 6.4 8.9 6.0 8.6 0.1 2.3 1.1 10.0 2.0 3.9 12.6 62.5 11.4 0.9 30.6 0.0 0.1 1.9 10.2 20.4 9.8 13.7 19.0 21.3 7.2 3.7 69.1 8.1 251.3 0.5 0.0 2.2 1.8 9.1 69.5 16.0 0.1 2.1 12.1 1.2 19.7 4.7 10.1 1.3 1.6 2.0 1.3 1.0 120.5 20.3 1.5 18.0 APOBEC3H ARP10 ENSG00000100298 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3H" Q6NTF7 22 39097224-39104067 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 6.6;dendritic cells: 9.6;Hofbauer cells: 4.9;monocytes: 10.5;NK-cells: 6.2;T-cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 9 "gdT-cell: 23.2;MAIT T-cell: 9.4;memory CD4 T-cell: 12.1;memory CD8 T-cell: 19.4;naive CD8 T-cell: 8.9;NK-cell: 19.7;T-reg: 11.9" "Group enriched" "Detected in many" 13 "NK-cells: 19.7;T-cells: 23.2" "Cell line enhanced" "Detected in some" "Daudi: 2.8;HDLM-2: 2.7;Karpas-707: 6.9;U-266/70: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021492, HPA058565" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "HPA021492: AB_10964888, HPA058565: " "unprognostic (7.09e-3)" "prognostic favorable (1.20e-4)" "unprognostic (1.05e-1)" "unprognostic (6.81e-4)" "unprognostic (3.40e-1)" "unprognostic (1.54e-3)" "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (3.83e-2)" "unprognostic (5.07e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (8.73e-12)" "unprognostic (1.05e-1)" "unprognostic (1.03e-1)" "unprognostic (6.55e-3)" "prognostic favorable (8.43e-7)" 0.7 0.8 0.3 2.3 0.5 3.6 0.6 1.0 0.7 0.7 0.0 1.8 0.5 0.8 3.6 1.1 1.3 1.6 0.5 0.3 0.3 0.8 0.6 2.4 3.8 0.7 0.4 0.5 0.3 0.6 0.7 1.0 0.6 0.7 3.3 0.6 0.9 1.5 0.6 0.5 1.2 1.2 0.2 3.1 0.9 1.6 0.5 2.9 0.7 0.0 2.1 1.4 0.6 0.5 0.0 0.5 0.0 0.0 0.0 0.2 2.0 0.0 0.1 0.2 0.0 0.0 0.2 2.8 1.0 0.3 0.0 0.1 0.0 0.6 0.0 2.7 0.3 0.7 0.1 0.0 0.2 0.0 2.0 1.8 1.6 0.2 0.2 0.2 0.0 0.1 0.0 6.9 0.9 0.9 1.4 0.2 0.0 0.0 0.0 1.6 0.0 0.2 0.0 1.3 0.0 0.0 0.1 0.0 0.0 1.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 4.8 0.7 0.2 0.2 1.2 0.1 0.1 0.3 0.0 23.2 0.5 9.4 1.4 12.1 19.4 0.2 0.4 0.6 8.9 0.0 19.7 1.6 0.0 11.9 4.7 0.3 0.5 1.0 0.7 0.3 0.3 0.7 0.4 0.6 0.2 0.5 0.5 0.4 0.0 4.2 0.0 1.6 0.1 0.6 0.9 1.2 0.0 0.2 0.3 0.1 0.0 2.4 0.0 0.0 6.6 9.6 0.1 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.4 0.3 0.0 0.6 0.1 0.5 0.1 3.8 0.1 0.4 0.2 4.9 0.0 0.2 0.0 2.0 1.0 0.6 0.5 0.0 1.0 0.0 0.0 10.5 0.0 6.2 0.0 0.1 0.0 0.0 0.0 2.7 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.9 0.1 0.2 0.2 0.0 1.5 20.8 0.0 0.0 0.5 CBX7 ENSG00000100307 "Chromobox 7" O95931 22 39120167-39152680 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 37.2;U-266/70: 30.7" "Low region specificity" "Detected in all" "CAB011574, HPA048677, HPA056480" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Cytosol "CAB011574: AB_726005, HPA048677: AB_2680490, HPA056480: AB_2683146" "prognostic favorable (6.18e-4)" "prognostic favorable (3.63e-4)" "prognostic unfavorable (3.73e-4)" "unprognostic (9.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.48e-3)" "unprognostic (4.76e-3)" "unprognostic (1.45e-2)" "unprognostic (3.86e-2)" "unprognostic (1.11e-3)" "prognostic favorable (1.04e-4)" "unprognostic (3.03e-3)" "prognostic favorable (2.45e-5)" "unprognostic (3.90e-1)" "unprognostic (1.26e-1)" "unprognostic (3.10e-1)" "unprognostic (1.63e-2)" 36.6 31.2 53.6 15.9 52.9 6.0 32.3 53.8 72.1 54.6 38.1 85.2 17.2 61.2 29.1 24.5 62.7 17.7 57.4 53.7 44.5 32.5 17.7 30.4 27.4 49.2 47.8 58.5 28.8 41.5 42.7 8.3 48.9 50.9 14.2 34.0 35.3 57.7 68.0 28.1 42.9 27.4 38.6 42.5 48.0 10.8 46.0 14.2 33.3 51.3 21.6 66.3 39.1 53.2 6.9 2.9 1.4 11.0 13.1 5.0 3.6 6.5 8.0 3.5 4.2 1.4 4.7 1.2 7.5 4.9 6.3 2.5 0.9 3.0 2.6 37.2 3.6 0.2 5.5 0.7 4.5 1.7 14.0 2.5 4.4 1.7 0.7 4.5 1.0 5.5 1.7 18.1 2.7 6.7 2.5 0.8 0.8 8.8 4.9 2.8 2.3 10.1 1.8 2.8 3.6 0.9 3.3 4.8 7.6 2.3 5.8 2.7 2.6 5.8 10.9 5.9 2.9 30.7 18.4 4.2 11.8 2.7 2.5 0.4 0.3 2.9 1.9 0.0 2.0 1.5 2.1 2.1 0.0 2.0 2.6 2.5 3.1 1.0 0.5 0.4 2.2 1.0 53.6 52.9 53.8 72.1 53.7 44.5 49.2 47.8 48.9 38.6 46.0 53.2 17.5 6.4 8.7 16.3 27.9 4.6 11.7 3.7 7.4 57.0 9.6 11.6 74.6 24.3 9.5 14.7 35.5 4.3 10.5 10.5 9.8 4.3 8.2 5.1 4.8 14.4 4.2 20.0 17.0 3.8 1.5 16.2 6.6 3.3 10.8 9.6 28.5 11.8 4.4 60.6 18.8 7.6 8.2 11.7 6.4 18.6 35.1 6.2 19.6 14.0 11.6 16.4 42.2 13.0 28.8 3.4 5.1 27.8 12.0 10.5 18.2 13.6 6.4 62.7 46.0 28.3 24.9 7.0 5.3 3.1 4.8 3.6 22.8 4.1 5.4 7.5 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 RPL3 L3 ENSG00000100316 "Ribosomal protein L3" P39023 22 39312882-39320389 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003365, HPA055361" Uncertain Supported Nucleoli,Cytosol NA NA 470000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Nucleoli, Cytosol" "HPA003365: AB_1079841, HPA055361: AB_2732594" "unprognostic (9.79e-3)" "unprognostic (2.06e-1)" "unprognostic (2.31e-1)" "unprognostic (1.68e-3)" "unprognostic (5.44e-3)" "unprognostic (1.72e-1)" "unprognostic (3.51e-2)" "unprognostic (1.22e-1)" "unprognostic (3.63e-1)" "unprognostic (5.81e-2)" "unprognostic (5.87e-2)" "unprognostic (7.09e-2)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (6.09e-2)" "unprognostic (2.72e-1)" "unprognostic (4.32e-2)" 2058.6 1934.3 965.6 1484.2 985.8 2965.1 2704.2 936.9 1071.1 2705.4 1023.2 2078.1 1515.1 2007.3 1653.7 2522.3 2423.9 1128.4 1326.4 894.6 951.2 1745.2 1894.1 1421.2 2460.9 984.1 951.1 4838.0 4514.8 1462.2 1861.5 1099.8 977.1 2180.0 1361.7 809.1 2210.1 1551.8 558.4 3337.9 1722.9 1388.1 1050.0 1824.1 1982.0 752.6 1002.9 2006.1 1709.0 417.1 2320.5 2012.9 2317.5 996.1 2010.5 1836.9 2035.9 2149.6 2535.3 5394.1 2745.1 1497.8 2703.5 1400.5 1249.7 2327.8 1425.1 8262.2 2062.9 1734.1 873.2 1246.8 2275.3 3060.5 923.2 1448.3 2207.4 2039.5 2153.8 3438.2 3887.7 2932.6 1619.9 5321.2 4063.7 1265.0 4504.5 3956.7 2765.5 2217.6 2407.8 2657.6 2135.0 2597.5 2974.5 4241.1 2054.6 2172.9 1273.8 2369.5 1924.0 4017.5 2609.2 2927.6 1823.4 2180.2 936.2 2925.4 5031.9 1242.2 2226.2 4761.3 2864.1 951.4 1534.4 1027.8 1788.2 2074.0 1741.6 3606.5 2111.3 2564.4 1093.9 638.7 1690.8 351.4 3488.7 1481.6 5383.7 5629.1 4993.5 4037.9 2821.8 5113.1 6376.7 5111.7 215.7 4472.3 1339.8 3182.6 3668.7 11623.3 965.6 985.8 936.9 1071.1 894.6 951.2 984.1 951.1 977.1 1050.0 1002.9 996.1 2118.4 984.0 2299.9 16.3 4551.5 10412.0 9836.0 9475.4 2792.1 1065.7 9967.6 10172.3 182.6 4213.6 3849.3 1441.9 425.4 5623.9 4123.0 1288.7 5893.0 2943.4 2097.6 1061.7 2644.4 3666.1 2726.6 2263.9 17.0 6539.7 7508.2 2678.8 1207.4 1390.0 1784.7 4203.6 3429.3 2085.8 3282.5 358.4 18.3 3696.8 2925.6 3062.8 6215.2 4622.8 5581.1 2203.8 5104.8 17.8 3733.3 2455.8 4243.1 9.5 25.1 3814.3 2946.3 3499.2 2308.1 8261.9 3481.6 5422.4 1350.6 1305.5 1577.7 4469.5 4329.1 1074.6 1014.8 3712.4 12290.3 5489.4 4201.1 4673.7 4830.3 9407.7 SYNGR1 ENSG00000100321 "Synaptogyrin 1" O43759 22 39349925-39385575 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "melanoma: 19.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "dendritic cells: 44.7;monocytes: 38.9;T-cells: 30.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029673, CAB034277" Enhanced Supported Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 6: T47d - Mammary gland" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB034277: AB_2255766, HPA029673: AB_10670430" "unprognostic (2.68e-3)" "unprognostic (1.84e-3)" "unprognostic (5.90e-2)" "unprognostic (8.51e-2)" "unprognostic (3.74e-1)" "unprognostic (5.98e-3)" "unprognostic (7.39e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "prognostic favorable (2.41e-4)" "unprognostic (1.16e-1)" "prognostic favorable (4.98e-7)" "unprognostic (1.32e-3)" "unprognostic (1.20e-1)" "unprognostic (2.02e-2)" "unprognostic (1.04e-1)" 9.9 24.6 73.2 4.9 84.9 92.9 14.7 64.7 121.8 36.2 25.3 26.7 5.9 22.1 11.6 37.3 23.5 11.3 57.0 84.7 37.5 26.2 5.3 8.6 7.5 35.1 37.9 72.7 28.0 29.8 15.2 6.5 36.5 29.6 4.3 73.0 45.1 18.0 29.0 51.8 11.8 13.2 6.3 10.6 16.6 19.8 58.4 3.5 11.6 26.4 9.9 25.6 34.9 67.1 5.4 9.6 17.3 31.1 1.7 4.4 7.5 23.2 40.8 29.2 26.9 2.1 0.6 0.2 5.3 6.1 3.3 7.6 11.8 0.5 8.8 0.1 36.6 0.4 0.8 1.0 4.9 1.6 10.5 6.7 1.8 7.9 0.0 20.7 1.4 6.8 11.0 0.7 4.6 12.5 4.8 4.5 3.6 4.8 18.7 14.0 0.0 1.5 0.9 15.0 27.1 5.5 6.1 25.1 23.7 7.1 36.9 27.3 0.5 0.0 19.6 0.3 0.1 6.4 0.2 15.2 0.8 30.2 31.6 0.6 38.9 0.8 30.8 11.8 1.7 5.8 1.1 9.1 44.7 4.2 1.3 15.3 1.7 5.1 0.6 33.1 0.2 18.0 73.2 84.9 64.7 121.8 84.7 37.5 35.1 37.9 36.5 6.3 58.4 67.1 8.9 9.6 1.1 28.4 21.0 30.3 73.6 33.8 39.3 112.9 61.4 73.0 73.6 75.8 31.4 66.2 27.1 25.0 52.5 0.1 15.6 57.2 40.0 14.3 24.4 9.5 0.0 92.9 57.1 12.3 14.4 44.6 1.5 18.5 2.5 49.0 12.1 5.9 14.2 47.1 47.1 0.3 12.2 20.0 13.8 87.9 133.3 11.7 140.5 20.6 10.1 46.8 91.6 39.7 18.7 21.7 1.1 119.2 23.2 36.4 0.1 9.3 7.5 38.6 19.7 46.8 30.6 62.8 14.7 57.1 37.4 13.1 21.2 131.6 0.4 80.2 TAB1 MAP3K7IP1 ENSG00000100324 "TGF-beta activated kinase 1 (MAP3K7) binding protein 1" Q15750 22 39399778-39437060 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032328, HPA039988, HPA057104" Approved Approved "Nuclear speckles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Nuclear speckles" "CAB032328: AB_2281637, HPA039988: AB_2676787, HPA057104: AB_2683338" "unprognostic (1.76e-1)" "unprognostic (1.79e-2)" "unprognostic (7.88e-2)" "unprognostic (6.73e-3)" "unprognostic (9.23e-3)" "unprognostic (4.30e-2)" "unprognostic (6.44e-2)" "unprognostic (1.79e-2)" "unprognostic (4.93e-2)" "unprognostic (7.05e-2)" "unprognostic (1.63e-1)" "unprognostic (7.35e-2)" "unprognostic (7.80e-3)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (1.33e-1)" "unprognostic (1.18e-1)" 13.1 14.8 18.2 9.0 20.6 9.7 12.9 17.0 19.8 18.2 10.6 18.9 10.7 16.5 6.2 13.8 15.9 7.4 17.0 17.3 16.1 12.4 16.6 11.0 11.1 18.7 19.3 20.5 15.6 10.0 10.5 8.6 17.7 16.7 5.4 12.2 13.7 10.9 19.9 17.4 13.5 8.7 15.8 15.9 14.7 10.2 18.5 11.9 13.3 10.7 7.8 17.9 14.9 20.6 15.0 15.3 15.2 17.5 15.8 13.2 13.5 12.3 15.1 18.4 17.3 14.2 10.6 22.5 9.4 12.0 10.3 18.0 15.5 18.0 7.2 17.6 24.8 9.9 19.0 14.2 13.7 18.8 18.3 13.5 15.7 13.9 15.1 14.0 13.6 13.5 18.4 15.0 9.3 9.7 14.6 15.6 10.6 23.6 15.4 26.0 21.6 22.6 14.4 15.7 13.5 9.9 17.4 21.5 15.4 9.4 17.6 20.4 11.8 12.8 20.2 9.9 10.1 23.6 16.2 16.4 15.1 13.1 12.8 0.8 5.6 4.1 4.3 4.3 3.4 3.3 2.6 3.5 5.0 3.2 4.1 3.9 0.7 3.3 4.5 2.3 2.8 4.3 18.2 20.6 17.0 19.8 17.3 16.1 18.7 19.3 17.7 15.8 18.5 20.6 6.0 3.2 6.7 17.9 7.0 2.0 2.8 4.0 6.8 55.2 5.9 6.9 7.4 8.6 4.1 3.7 18.8 12.4 4.7 4.9 0.0 6.2 1.6 4.5 7.0 5.4 11.4 6.9 9.1 3.8 7.9 6.2 7.1 4.4 5.1 12.5 2.2 4.7 7.1 28.6 12.6 4.8 0.0 6.0 1.0 3.2 7.8 6.4 5.4 9.4 8.6 12.1 8.2 7.5 18.6 5.4 4.1 9.1 8.4 2.8 7.6 5.4 4.7 18.8 6.6 6.4 7.4 8.2 9.1 5.5 3.3 5.6 8.1 10.3 4.9 1.8 MGAT3 GNT-III ENSG00000128268 "Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase" Q09327 22 39457012-39492194 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.0;intestine: 28.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 44.8;Bipolar cells: 30.7;Excitatory neurons: 25.1;Inhibitory neurons: 27.4;Oligodendrocytes: 45.7;Proximal enterocytes: 37.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4;eosinophil: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 65.1;HMC-1: 56.0;OE19: 58.8;U-266/70: 73.6;U-266/84: 32.6;U-698: 32.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017598 Approved "Intracellular and membrane" NA NA 170000 "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "HPA017598: AB_1853853" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (4.79e-2)" "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (5.71e-3)" "unprognostic (8.92e-2)" "unprognostic (2.17e-1)" "unprognostic (4.35e-3)" "unprognostic (6.77e-2)" "unprognostic (8.12e-3)" "unprognostic (8.74e-2)" "prognostic unfavorable (5.04e-8)" "unprognostic (6.73e-2)" "unprognostic (1.46e-1)" "unprognostic (5.89e-2)" "unprognostic (4.92e-2)" 7.8 1.1 26.8 4.0 20.9 10.8 6.4 7.6 47.0 6.2 0.0 5.2 21.5 3.8 0.8 1.1 3.4 3.8 4.8 30.3 10.0 3.0 0.2 14.9 7.6 28.1 15.6 1.2 3.1 0.4 1.8 10.5 21.8 1.2 4.6 6.7 1.8 1.0 1.5 2.3 28.4 2.8 4.8 4.8 7.4 5.4 23.9 1.8 1.5 1.8 9.0 1.6 1.5 27.3 0.3 0.4 10.4 1.0 0.0 0.0 65.1 0.5 0.7 0.5 0.0 14.9 3.7 23.4 8.1 0.0 0.2 1.3 5.4 0.0 0.1 0.0 0.5 18.9 0.0 0.2 0.2 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 15.8 2.9 0.0 0.2 0.6 1.4 3.1 58.8 0.0 1.2 0.0 3.9 0.4 0.6 6.0 4.4 0.0 0.0 0.0 18.5 0.8 1.0 0.0 0.1 8.1 0.1 0.1 73.6 32.6 32.6 0.2 0.1 1.7 1.4 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 26.8 20.9 7.6 47.0 30.3 10.0 28.1 15.6 21.8 4.8 23.9 27.3 2.0 44.8 3.0 6.5 2.2 0.4 0.1 1.8 0.0 30.7 0.6 1.1 1.9 1.5 3.7 0.0 6.2 5.5 0.0 4.1 0.0 0.0 19.1 0.9 11.0 2.5 7.8 13.7 25.1 0.2 12.0 2.3 10.2 2.0 2.5 0.0 0.0 0.0 1.5 13.5 27.4 3.8 2.0 0.0 2.3 16.6 4.4 0.9 0.0 0.0 0.1 1.5 0.0 21.6 45.7 1.8 6.1 3.8 1.7 0.3 37.4 1.8 5.2 2.3 6.6 0.3 4.3 0.7 1.2 0.2 0.6 3.7 0.5 0.6 4.5 1.5 MIEF1 "FLJ20232, L0R8F8, MiD51, SMCR7L" ENSG00000100335 "Mitochondrial elongation factor 1" Q9NQG6 22 39499432-39518132 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 266.3;Late spermatids: 377.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061059 Approved "Intermediate filaments,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Intermediate filaments, Mitochondria" "HPA061059: " "unprognostic (5.35e-2)" "unprognostic (2.66e-2)" "unprognostic (2.86e-3)" "unprognostic (1.11e-2)" "unprognostic (3.74e-2)" "unprognostic (1.49e-1)" "unprognostic (1.95e-3)" "unprognostic (1.85e-2)" "unprognostic (5.72e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-1)" "unprognostic (6.65e-2)" "prognostic favorable (3.96e-5)" "unprognostic (1.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.30e-1)" 9.6 8.1 10.9 7.9 10.4 12.8 8.4 10.9 10.4 6.3 8.5 9.5 12.0 7.6 6.8 9.3 7.1 5.5 8.8 10.2 9.9 13.1 16.3 7.4 11.2 10.4 11.5 7.7 9.5 10.9 5.1 8.6 11.1 6.9 9.3 8.3 9.8 8.1 8.4 7.9 10.4 6.8 10.8 9.2 8.2 17.1 11.4 9.5 8.4 9.3 11.7 7.3 6.3 10.3 16.0 15.9 16.5 26.6 15.5 17.0 19.5 15.0 17.4 16.7 15.0 25.9 8.1 44.4 12.2 15.7 10.9 20.0 37.6 20.4 20.1 18.8 36.3 18.1 22.4 26.2 30.1 63.7 23.1 22.3 24.3 14.7 30.7 16.1 17.9 14.5 32.5 23.4 16.7 11.0 20.5 17.8 15.4 32.5 17.2 27.7 23.4 44.6 19.0 18.8 15.3 12.7 16.6 27.6 42.8 17.3 12.3 22.7 17.8 15.7 22.1 14.0 18.6 42.2 47.5 43.9 18.1 28.0 24.7 0.4 5.6 4.7 5.2 6.2 6.4 4.8 5.0 5.1 6.0 4.7 5.4 5.1 0.4 6.8 6.2 3.3 4.7 6.3 10.9 10.4 10.9 10.4 10.2 9.9 10.4 11.5 11.1 10.8 11.4 10.3 10.9 12.8 18.7 7.5 13.6 19.5 16.0 11.4 10.8 19.0 13.6 12.1 19.3 20.0 8.6 16.5 25.0 19.6 17.0 22.0 25.4 13.1 266.3 5.2 14.3 13.1 9.7 14.7 7.4 13.8 19.8 10.4 8.2 8.9 9.5 14.2 16.8 49.8 15.8 6.7 8.3 11.5 24.4 20.7 20.5 377.2 15.5 12.2 16.0 9.4 19.0 18.7 7.2 2.0 8.9 17.6 7.6 13.9 29.1 23.4 21.9 27.8 8.9 15.2 0.0 14.1 10.2 20.4 28.0 16.2 23.0 13.0 10.8 14.7 20.7 19.1 AL022312.1 ENSG00000285025 "Novel protein" L0R8F8 22 39504231-39504443 "Predicted intracellular proteins" "Ribosome biogenesis, Translation regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 26 "brain: 1.6;choroid plexus: 1.3;skeletal muscle: 4.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.6" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HeLa: 1.8;MOLT-4: 6.6;REH: 1.2;U-698: 1.8" "Not detected" "Not detected" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.3 1.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.7 0.0 0.1 0.5 0.1 0.0 0.5 0.0 1.6 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011596 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centriolar satellite, Cytosol" "CAB011596: AB_725569" "unprognostic (2.51e-2)" "unprognostic (7.36e-2)" "unprognostic (1.79e-1)" "unprognostic (1.09e-1)" "unprognostic (4.45e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (4.43e-2)" "unprognostic (1.97e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.41e-1)" "prognostic unfavorable (9.77e-5)" "unprognostic (7.06e-2)" "unprognostic (9.78e-2)" "unprognostic (6.40e-2)" "unprognostic (1.95e-1)" 582.7 408.4 322.1 204.1 337.9 888.2 488.9 349.4 416.4 362.4 319.2 853.9 215.2 389.2 232.2 391.5 381.8 245.6 389.9 316.2 328.3 393.7 492.9 438.0 223.9 353.2 336.7 346.1 629.0 202.6 304.7 247.8 346.6 454.8 218.4 497.5 472.4 278.6 789.2 370.6 362.7 347.4 336.5 351.1 574.5 154.1 339.1 243.7 317.8 420.8 280.6 572.8 363.9 366.3 398.5 230.6 412.3 532.3 450.0 437.1 670.3 470.5 726.2 366.8 462.1 508.5 300.0 760.2 100.7 358.0 300.6 305.1 676.3 551.9 463.7 475.2 461.0 518.9 259.5 516.8 962.7 992.0 479.4 733.3 1172.0 654.3 973.2 658.2 365.8 825.3 560.4 790.7 288.6 241.8 599.2 713.8 354.8 828.1 288.3 612.0 268.5 793.5 491.0 328.0 605.3 254.3 214.8 559.3 1405.8 374.4 342.4 1191.5 290.4 221.5 645.9 250.8 323.8 1004.7 1100.7 888.7 244.9 497.5 506.3 46.5 36.9 24.8 20.0 31.6 26.4 37.9 27.6 26.5 44.3 28.7 28.6 26.6 17.8 26.8 34.9 27.0 31.6 28.8 322.1 337.9 349.4 416.4 316.2 328.3 353.2 336.7 346.6 336.5 339.1 366.3 201.0 169.9 176.0 19.2 181.8 443.9 344.3 171.2 205.5 120.5 286.8 211.5 167.9 143.0 148.7 44.1 93.8 140.1 156.9 357.9 66.5 200.9 20.9 154.2 122.8 229.9 266.7 140.4 19.2 765.1 309.0 198.0 184.5 191.7 223.0 119.0 146.7 190.9 112.7 69.0 16.6 371.4 101.7 174.3 348.4 21.1 185.1 215.7 238.3 22.5 239.5 94.7 92.7 16.6 34.7 396.0 335.7 206.9 223.7 378.5 265.0 85.8 92.3 311.3 335.2 306.5 279.0 72.3 61.5 155.3 335.7 218.4 175.5 115.0 284.5 401.1 RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042874 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" Nucleoplasm "HPA042874: AB_10793988" "unprognostic (2.44e-1)" "unprognostic (1.67e-1)" "unprognostic (7.79e-2)" "unprognostic (5.07e-3)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.71e-4)" "unprognostic (1.65e-1)" "unprognostic (5.68e-2)" "unprognostic (8.31e-2)" "unprognostic (7.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.04e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (4.32e-2)" 98.5 123.0 122.2 43.1 124.5 61.7 94.6 126.7 159.0 73.5 115.9 117.1 43.5 65.5 31.5 94.2 65.6 19.3 114.6 121.2 119.7 123.1 158.5 80.4 48.0 126.5 124.2 68.9 109.6 47.1 66.5 30.2 123.7 108.1 19.2 23.9 94.4 42.8 104.7 80.0 78.3 19.7 124.8 100.5 101.5 65.8 128.4 40.5 96.7 45.4 34.6 99.9 73.7 123.9 94.8 117.6 54.5 80.4 60.7 39.7 110.8 102.0 87.3 92.5 74.0 131.1 62.1 118.9 107.4 64.5 74.8 73.8 87.8 111.3 32.2 163.8 261.5 110.0 105.5 118.0 88.2 166.8 142.3 60.1 83.1 80.3 96.8 49.4 64.9 87.6 128.0 83.8 61.0 108.0 80.6 164.1 95.1 210.9 209.5 127.3 70.0 182.0 99.7 95.8 121.2 66.9 85.8 137.3 203.1 33.6 98.8 134.8 74.0 77.5 168.8 85.7 141.7 140.3 145.4 188.4 103.3 116.8 183.1 126.8 147.4 187.3 133.0 141.6 123.5 159.7 135.1 140.6 122.4 173.9 129.9 132.8 168.7 128.9 119.4 193.1 165.1 138.3 122.2 124.5 126.7 159.0 121.2 119.7 126.5 124.2 123.7 124.8 128.4 123.9 113.6 44.8 51.4 13.1 109.5 137.1 94.3 124.3 84.2 98.0 178.6 205.7 73.8 105.8 83.0 97.5 52.1 152.9 114.7 205.5 217.2 174.9 23.6 68.6 69.8 121.0 142.6 83.5 8.7 192.2 231.9 92.0 76.0 81.6 69.8 62.0 116.0 184.8 204.3 35.3 10.9 207.5 130.2 116.4 233.3 40.3 137.0 110.8 108.5 8.4 147.8 139.1 162.7 5.5 18.7 233.5 202.2 126.0 193.3 206.8 274.9 362.2 54.0 103.7 78.9 74.4 100.9 61.6 138.0 87.6 147.9 131.6 115.2 103.1 165.9 132.4 CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;thyroid gland: 5.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 16.9;Excitatory neurons: 16.8;Inhibitory neurons: 12.3" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-BR-3: 1.9;T-47d: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066992 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Cell Junctions" "HPA066992: " "unprognostic (3.97e-2)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-1)" "unprognostic (7.21e-2)" "unprognostic (5.20e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-2)" "unprognostic (6.14e-3)" "unprognostic (1.57e-1)" "unprognostic (3.78e-2)" "unprognostic (8.27e-4)" 0.2 3.3 5.0 0.8 5.6 0.6 0.1 1.5 9.7 0.1 0.0 0.5 0.1 0.1 0.0 0.2 0.2 0.1 0.0 8.7 1.3 0.1 0.0 0.5 1.9 7.6 1.4 0.0 0.1 0.0 0.3 0.0 7.9 0.1 0.0 2.6 0.1 0.0 0.0 0.2 3.3 0.0 0.7 1.5 0.6 0.8 2.2 0.2 5.3 0.0 0.5 0.4 0.2 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 5.0 5.6 1.5 9.7 8.7 1.3 7.6 1.4 7.9 0.7 2.2 4.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 16.9 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.4 16.8 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 3.3 12.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 1.0 2.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.1 ENTHD1 FLJ25421 ENSG00000176177 "ENTH domain containing 1" Q8IYW4 22 39743044-39893864 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 11.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.2;granulocytes: 8.9;Late spermatids: 17.5;Spermatocytes: 37.4;Spermatogonia: 6.7" "Cancer enriched" "Detected in single" 30 "melanoma: 7.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "SK-MEL-30: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA019800 Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "HPA019800: AB_1848842" "unprognostic (5.28e-3)" "unprognostic (1.27e-1)" "unprognostic (8.04e-2)" "unprognostic (9.84e-3)" "unprognostic (2.97e-4)" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (2.17e-1)" "unprognostic (7.32e-2)" "unprognostic (1.47e-4)" "unprognostic (3.60e-2)" "unprognostic (7.75e-10)" "unprognostic (3.68e-2)" "unprognostic (8.56e-2)" "unprognostic (4.99e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 11.0 0.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 8.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 17.5 0.6 1.1 0.0 0.0 0.7 0.0 0.0 1.5 0.2 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 37.4 6.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 32.6;granulocytes: 146.9;Macrophages: 82.0;NK-cells: 59.8;T-cells: 57.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Group enriched" "Detected in some" 4 "HEL: 45.7;JURKAT: 175.8;K-562: 44.8;MOLT-4: 122.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" 1.2 0.7 0.2 7.9 0.2 10.3 2.0 0.2 0.3 1.5 0.5 2.2 3.6 0.8 0.5 1.2 0.7 2.6 1.1 0.2 0.3 0.6 1.2 4.4 15.7 0.6 0.3 0.2 0.4 0.1 0.3 0.6 0.5 1.6 2.3 0.3 1.7 0.7 0.4 1.1 4.5 0.9 0.5 9.3 3.8 1.9 0.4 184.8 0.8 0.5 12.9 3.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 45.7 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.2 0.3 0.0 175.8 44.8 0.0 0.0 0.0 122.8 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 6.3 0.7 0.1 51.4 0.3 38.2 3.1 37.5 56.2 1.2 5.2 31.3 58.2 6.6 5.4 0.3 0.8 35.0 74.9 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.3 0.5 0.5 0.4 0.7 1.1 0.0 6.7 0.3 8.2 1.7 0.0 0.0 0.0 0.6 1.1 0.8 1.0 2.8 0.0 0.0 0.0 0.0 18.3 0.1 0.0 0.4 4.8 0.3 0.1 0.8 1.2 32.6 1.3 0.2 0.0 0.6 0.0 0.1 146.9 0.2 2.5 2.3 0.2 0.0 1.2 0.6 0.0 1.9 4.6 2.9 0.3 82.0 1.8 1.0 6.8 0.3 59.8 2.5 1.0 0.0 0.3 0.4 6.3 0.4 0.0 0.4 0.0 0.0 0.0 0.5 0.9 4.4 2.1 0.1 1.1 0.1 57.1 0.0 0.1 0.3 Z82206.1 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964718 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;lymphoid tissue: 4.3" "Cell type enhanced" "Detected in some" "Distal tubular cells: 7.9;granulocytes: 3.8;Proximal tubular cells: 3.2;T-cells: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 4 "K-562: 12.5" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: AB_2680029" "unprognostic (8.48e-4)" "unprognostic (2.95e-6)" "unprognostic (3.67e-1)" "unprognostic (5.90e-2)" "unprognostic (4.27e-1)" "unprognostic (6.95e-3)" "unprognostic (3.74e-1)" "unprognostic (5.41e-4)" "unprognostic (2.33e-1)" "unprognostic (2.13e-2)" "unprognostic (1.18e-3)" "unprognostic (8.77e-2)" "unprognostic (6.53e-5)" "unprognostic (1.89e-1)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (6.58e-3)" 0.1 0.0 0.0 0.2 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 1.1 0.1 0.1 0.0 4.3 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.4 12.5 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 1.1 2.7 2.9 1.3 2.5 2.3 3.5 3.2 1.6 2.0 3.6 4.4 2.4 1.3 1.2 1.7 2.6 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.9 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 FAM83F ENSG00000133477 "Family with sequence similarity 83 member F" Q8NEG4 22 39994954-40043534 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3;testis: 40.8" "Cell type enhanced" "Detected in many" "Late spermatids: 68.1;Proximal enterocytes: 39.9;Suprabasal keratinocytes: 34.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 12.1;HaCaT: 12.8;HBEC3-KT: 15.5;hTCEpi: 37.9;hTERT-HME1: 11.8;OE19: 17.6;RT4: 18.6;SCLC-21H: 39.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051207, HPA064657" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Nucleoplasm "HPA051207: AB_2681388, HPA064657: AB_2685313" "unprognostic (2.78e-2)" "unprognostic (3.91e-2)" "prognostic favorable (1.73e-4)" "unprognostic (5.36e-2)" "unprognostic (1.48e-5)" "unprognostic (1.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.75e-2)" "unprognostic (4.79e-1)" "unprognostic (2.48e-1)" "prognostic favorable (9.40e-4)" "unprognostic (3.25e-1)" "unprognostic (1.10e-7)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (2.98e-2)" "unprognostic (8.32e-2)" 1.2 0.1 0.2 0.5 0.1 1.2 4.7 0.3 0.2 2.6 0.1 5.3 3.2 0.2 2.5 20.3 1.2 0.5 2.0 0.2 0.1 4.0 2.9 0.2 0.0 0.1 0.1 0.3 13.5 5.4 1.2 0.1 0.1 9.0 3.2 0.4 8.2 6.6 0.1 18.8 7.6 0.1 0.0 0.0 6.8 40.8 0.3 0.9 5.9 0.2 1.1 2.6 7.0 0.3 8.3 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 12.1 2.3 0.0 0.0 0.0 0.0 12.8 0.0 15.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 37.9 0.0 11.8 0.0 0.0 2.0 0.0 0.1 0.0 0.0 0.0 0.1 2.1 17.6 0.0 0.0 0.0 0.1 0.3 18.6 39.8 0.0 0.3 3.4 0.0 1.3 2.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.0 0.3 0.3 1.1 0.0 0.0 0.0 0.5 28.7 14.5 18.0 23.9 1.2 19.1 10.4 5.2 12.8 7.4 23.9 0.0 0.2 0.0 33.1 3.9 9.6 28.4 6.2 0.5 1.0 13.1 0.4 0.2 15.1 0.2 1.0 10.7 6.5 1.3 0.2 0.0 2.2 0.2 0.0 0.2 21.0 14.2 0.6 2.9 68.1 1.8 0.5 1.8 0.0 0.0 0.9 0.0 0.5 0.1 12.5 21.6 2.2 0.2 16.3 39.9 5.9 6.4 0.6 0.0 1.1 1.3 12.4 1.8 30.6 34.5 1.4 0.8 0.4 15.6 17.8 TNRC6B KIAA1093 ENSG00000100354 "Trinucleotide repeat containing adaptor 6B" Q9UPQ9 22 40044817-40335808 "Metabolic proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 484.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003180 Approved NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "HPA003180: AB_1079196" "unprognostic (1.45e-1)" "unprognostic (1.29e-2)" "unprognostic (1.04e-1)" "unprognostic (5.88e-2)" "unprognostic (1.92e-2)" "unprognostic (3.27e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-2)" "unprognostic (9.74e-2)" "unprognostic (4.93e-2)" "unprognostic (2.59e-1)" "unprognostic (8.42e-2)" "unprognostic (1.84e-3)" "unprognostic (8.85e-2)" "unprognostic (7.24e-2)" "unprognostic (7.00e-2)" "unprognostic (1.81e-1)" 4.0 3.6 4.5 4.9 6.2 19.5 3.9 22.0 7.6 4.4 13.2 4.2 3.2 4.0 5.8 3.5 3.7 4.4 4.7 3.6 1.1 3.9 5.4 4.9 5.3 3.7 3.5 4.2 3.9 4.7 5.5 3.6 4.2 3.7 3.5 12.7 4.0 2.8 6.4 5.5 5.2 3.7 1.1 5.6 4.3 14.9 3.9 9.2 5.0 5.1 5.9 3.6 4.2 15.7 6.3 9.3 9.4 9.8 6.1 4.3 5.1 4.2 7.7 6.5 7.9 4.2 4.3 11.9 7.4 5.1 7.6 4.3 11.8 8.6 6.8 13.0 9.3 8.8 9.3 5.3 3.0 10.2 12.5 4.8 4.0 10.2 5.1 3.1 9.0 6.7 7.4 10.8 6.1 6.8 6.3 3.2 12.2 4.8 6.7 7.7 9.0 6.0 6.1 10.6 11.4 2.7 10.2 3.6 5.2 8.5 5.1 3.7 10.3 5.7 20.7 5.8 4.0 8.5 8.2 7.8 3.7 5.1 6.8 228.9 32.8 66.2 48.0 19.2 42.4 100.7 50.5 44.5 16.3 134.6 52.8 53.6 484.5 34.7 29.6 104.9 29.5 12.5 4.5 6.2 22.0 7.6 3.6 1.1 3.7 3.5 4.2 1.1 3.9 15.7 114.0 38.5 54.9 260.8 178.8 74.8 70.2 60.8 92.8 248.7 103.4 85.9 153.6 125.8 56.0 69.9 458.7 36.4 171.1 77.8 70.5 59.8 82.5 142.2 91.0 104.4 141.0 203.1 334.1 59.3 20.7 108.4 61.2 85.0 65.9 78.1 120.7 109.7 39.0 341.6 371.8 76.7 65.1 115.9 80.1 72.4 111.9 71.4 65.8 235.2 117.2 127.2 168.9 255.9 304.0 54.4 76.4 127.9 117.8 79.8 93.0 69.0 91.3 356.9 52.6 175.5 95.1 87.7 88.3 56.6 82.1 7.5 149.0 82.6 83.7 59.1 ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346461-40390463 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 345.1;tongue: 242.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 440000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "CAB019285: , HPA000525: AB_1078106" "unprognostic (2.80e-1)" "unprognostic (2.12e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (6.87e-3)" "prognostic unfavorable (5.81e-8)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (6.28e-2)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (8.43e-2)" "unprognostic (2.70e-1)" "unprognostic (4.06e-1)" "unprognostic (1.44e-2)" 29.8 33.9 10.6 31.1 11.2 40.6 33.1 12.5 13.3 30.7 12.9 36.5 22.7 34.9 21.9 29.8 33.5 20.6 47.4 10.9 10.6 33.6 32.1 22.7 46.9 10.5 11.7 33.5 45.2 29.3 22.0 30.2 10.9 23.8 35.4 10.3 25.7 22.3 345.1 22.2 28.8 41.1 10.0 33.5 28.0 29.2 10.5 50.5 29.6 242.3 48.5 36.0 25.2 10.8 98.0 110.2 88.3 124.9 62.6 89.5 106.5 82.0 85.2 187.3 138.1 189.0 51.9 279.0 73.2 102.3 84.9 67.3 203.5 137.4 187.7 75.3 197.5 126.5 98.4 166.5 134.6 423.0 96.3 97.7 76.5 161.5 169.8 91.3 138.9 127.3 153.1 114.3 136.4 105.0 130.2 131.2 152.5 121.3 119.3 195.1 203.6 198.2 118.9 67.8 58.8 54.4 106.2 54.1 170.7 78.5 76.8 134.7 91.2 93.3 173.7 85.3 168.8 109.0 212.6 218.2 80.9 149.5 97.7 29.0 47.2 19.9 35.5 55.2 49.5 34.6 76.1 48.5 68.1 33.5 58.3 45.0 4.1 48.2 49.7 34.4 81.7 62.3 10.6 11.2 12.5 13.3 10.9 10.6 10.5 11.7 10.9 10.0 10.5 10.8 10.0 12.8 10.8 9.4 28.3 18.1 18.8 48.6 23.9 16.1 14.8 15.0 30.0 30.0 20.8 3.7 37.5 85.3 15.5 13.0 7.9 61.3 44.0 5.6 9.2 21.6 13.8 54.6 11.4 43.7 78.9 21.2 21.4 5.6 36.8 8.8 28.9 25.6 60.3 6.7 10.7 24.1 24.4 44.8 26.7 25.2 24.8 22.7 12.4 1.0 41.9 45.1 19.6 9.5 9.8 33.7 15.6 14.3 52.4 21.3 21.4 19.7 12.3 18.1 26.3 38.5 20.8 61.2 82.8 35.7 15.2 33.1 32.2 8.7 37.7 14.1 SGSM3 "DJ1042K10.2, RabGAP-5, RABGAP5, RUSC3, RUTBC3" ENSG00000100359 "Small G protein signaling modulator 3" Q96HU1 22 40370591-40410289 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 176.4;Intestinal goblet cells: 135.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048980 Approved Supported "Golgi apparatus" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus" "HPA048980: AB_2680585" "unprognostic (4.63e-2)" "unprognostic (7.51e-3)" "unprognostic (3.02e-2)" "prognostic favorable (4.47e-5)" "unprognostic (1.81e-1)" "unprognostic (6.83e-3)" "unprognostic (5.70e-3)" "unprognostic (7.53e-2)" "unprognostic (3.57e-1)" "unprognostic (5.67e-2)" "unprognostic (1.71e-3)" "unprognostic (1.93e-1)" "unprognostic (2.97e-1)" "unprognostic (4.08e-3)" "unprognostic (2.10e-1)" "unprognostic (1.63e-1)" "unprognostic (5.98e-3)" 24.8 42.6 34.6 26.1 34.8 19.3 29.4 27.3 43.6 37.3 32.6 46.6 32.8 31.9 14.5 49.2 37.1 28.7 37.0 33.2 33.3 36.4 37.3 33.8 32.9 36.5 34.3 30.8 107.7 24.7 55.0 21.9 34.8 62.6 24.3 11.0 70.1 25.9 34.2 36.7 46.1 17.4 27.6 51.5 91.4 39.8 33.6 27.5 48.7 23.4 28.3 33.1 35.6 31.9 37.8 21.1 30.6 34.1 33.2 18.1 43.4 35.0 22.9 26.0 33.7 12.0 30.9 23.3 23.7 37.9 15.6 30.0 29.2 42.9 10.4 58.4 68.8 15.9 56.9 11.3 31.6 23.1 33.1 30.2 29.5 29.1 17.4 29.2 46.0 48.6 19.8 31.4 19.4 60.5 32.1 23.5 20.5 75.8 14.0 59.3 19.3 51.1 26.8 33.0 18.8 24.2 38.6 55.4 27.5 24.2 46.3 38.9 40.2 8.8 31.8 23.4 20.6 47.1 23.2 31.0 37.4 19.0 22.9 1.1 14.6 16.3 18.7 15.7 15.6 17.7 11.5 14.9 18.9 22.3 13.8 11.3 3.3 35.4 11.9 31.6 11.7 15.8 34.6 34.8 27.3 43.6 33.2 33.3 36.5 34.3 34.8 27.6 33.6 31.9 5.3 3.2 10.3 14.0 32.8 11.5 32.4 33.1 14.8 57.0 12.1 7.1 8.3 27.1 42.1 7.3 18.8 42.8 23.9 46.4 1.9 20.2 17.5 5.1 3.8 14.3 31.3 18.1 27.1 45.3 54.3 14.0 176.4 6.7 15.9 3.1 21.8 24.0 24.2 26.9 34.6 135.3 50.8 17.2 8.3 31.7 22.7 11.8 16.0 13.1 21.6 13.4 30.9 15.6 15.1 21.3 40.6 19.2 30.5 46.1 36.2 4.4 60.2 34.0 39.5 14.4 13.8 83.5 44.4 19.8 10.4 45.6 16.7 3.3 47.7 60.0 MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 4.5;Cardiomyocytes: 8.7;Cytotrophoblasts: 8.9;Extravillous trophoblasts: 8.7;Fibroblasts: 4.3;Hofbauer cells: 12.7;Syncytiotrophoblasts: 7.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.4" "Group enriched" "Detected in all" 5 "dendritic cells: 93.1;granulocytes: 189.4;monocytes: 58.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030782 Approved Supported Nucleoplasm,Cytosol No No "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA030782: AB_10600930" "unprognostic (7.90e-3)" "unprognostic (4.51e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (9.04e-2)" "unprognostic (9.37e-2)" "unprognostic (4.38e-3)" "unprognostic (1.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-2)" "prognostic unfavorable (1.58e-7)" "unprognostic (9.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.30e-2)" "unprognostic (3.98e-1)" 21.1 15.4 15.8 27.3 18.0 80.7 19.9 10.9 22.8 25.5 12.3 20.8 11.7 33.1 7.3 16.6 22.6 11.7 21.3 20.2 10.0 14.6 12.3 24.5 27.5 9.3 8.7 20.9 16.1 8.9 13.8 18.3 7.9 19.4 8.8 11.1 18.2 15.2 19.1 24.4 18.6 16.3 6.7 29.7 19.1 35.9 9.5 21.7 22.1 8.0 22.8 22.0 19.6 15.3 26.5 33.9 14.5 17.5 21.6 15.9 27.8 25.6 16.6 23.1 22.8 19.1 7.9 27.2 10.2 27.0 20.3 35.5 12.7 31.9 13.8 32.0 29.2 46.3 39.9 24.7 17.8 53.5 79.8 15.5 36.7 22.4 15.1 17.5 18.3 15.0 12.9 12.3 11.5 25.3 20.7 57.4 11.7 14.2 12.1 35.4 17.5 16.4 16.9 22.1 8.7 8.7 43.7 19.4 13.8 18.3 16.0 59.0 27.8 14.7 38.7 21.4 20.9 16.1 16.5 39.1 12.1 25.6 26.5 49.0 53.5 189.4 18.5 43.7 16.9 13.0 15.8 13.6 64.3 18.6 21.1 18.1 57.2 16.8 58.8 93.1 22.0 34.2 15.8 18.0 10.9 22.8 20.2 10.0 9.3 8.7 7.9 6.7 9.5 15.3 4.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 8.9 3.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 8.7 4.3 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 7.8 0.6 0.0 0.0 0.0 MCHR1 "GPR24, MCH1R, SLC1" ENSG00000128285 "Melanin concentrating hormone receptor 1" Q99705 22 40678750-40682814 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;endometrium 1: 3.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.7;Hepatic stellate cells: 2.2;Inhibitory neurons: 4.3;Leydig cells: 2.8;Melanocytes: 8.8;Microglial cells: 2.8;Oligodendrocyte precursor cells: 2.0" "Group enriched" "Detected in some" 7 "glioma: 4.9;liver cancer: 1.5;melanoma: 3.1;renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;RH-30: 1.6;SuSa: 4.7;T-47d: 1.4;U-87 MG: 1.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.9" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (2.45e-3)" "unprognostic (2.68e-1)" "unprognostic (2.84e-3)" "unprognostic (4.92e-3)" "unprognostic (4.51e-3)" "unprognostic (1.19e-2)" "unprognostic (1.58e-2)" "unprognostic (9.35e-4)" "unprognostic (3.05e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (3.07e-2)" "unprognostic (5.40e-2)" "unprognostic (2.42e-1)" "unprognostic (3.91e-2)" 0.3 0.1 2.0 0.3 2.5 0.0 0.1 1.8 3.7 0.4 0.5 0.1 0.1 3.6 0.4 0.0 0.7 0.0 2.2 2.6 3.5 0.1 1.3 0.2 0.2 1.8 1.5 2.4 0.0 0.0 2.1 0.0 2.6 0.0 0.0 1.2 0.1 0.0 0.1 0.5 0.1 0.7 1.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.2 0.1 1.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.5 1.8 3.7 2.6 3.5 1.8 1.5 2.6 1.0 2.0 1.6 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.1 0.0 0.4 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 3.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 2.2 1.2 0.1 0.0 4.3 0.0 0.0 0.0 0.3 0.0 2.8 0.0 8.8 2.8 0.0 1.6 0.0 2.0 0.6 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 SLC25A17 PMP34 ENSG00000100372 "Solute carrier family 25 member 17" O43808 22 40769630-40819399 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052708, HPA060972" Approved Supported Peroxisomes NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Peroxisomes "HPA052708: AB_2681924, HPA060972: AB_2684400" "unprognostic (2.75e-1)" "unprognostic (1.11e-3)" "unprognostic (1.91e-3)" "unprognostic (2.44e-2)" "unprognostic (2.61e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (1.63e-3)" "unprognostic (8.44e-2)" "unprognostic (2.72e-1)" "unprognostic (5.59e-2)" "unprognostic (8.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" 7.4 12.3 9.4 5.3 9.2 3.3 14.3 9.9 10.7 9.3 11.5 6.3 5.4 13.2 19.6 7.1 11.4 5.7 4.3 9.2 10.2 13.6 16.9 6.6 9.4 9.9 9.6 20.6 8.8 13.6 9.2 10.0 9.7 10.7 7.3 9.2 9.8 5.9 3.9 9.6 6.0 10.5 10.1 7.3 7.8 10.0 10.0 9.3 12.7 3.6 9.7 8.1 7.2 11.2 23.5 13.5 21.0 18.5 12.8 15.9 16.8 20.7 22.7 32.5 35.7 16.5 8.8 26.7 12.2 20.4 17.7 18.6 30.6 16.6 33.4 27.0 41.3 31.1 18.4 21.1 18.3 35.8 16.2 15.3 22.8 28.6 18.4 14.7 19.4 21.4 46.5 12.9 26.5 19.2 22.0 24.2 17.7 33.2 20.6 23.8 32.4 40.3 27.6 19.7 14.2 12.5 42.8 26.6 26.7 20.3 22.0 10.7 11.8 18.5 24.4 16.1 19.2 13.9 29.6 25.7 19.7 18.4 20.4 7.0 3.3 4.2 4.9 3.9 6.9 8.4 5.8 5.5 4.2 7.6 8.2 6.7 1.5 8.3 3.3 5.4 8.6 4.7 9.4 9.2 9.9 10.7 9.2 10.2 9.9 9.6 9.7 10.1 10.0 11.2 8.4 19.2 9.5 23.2 10.9 16.6 16.8 29.8 10.8 12.1 13.6 9.3 4.0 7.2 20.7 12.9 8.4 39.8 8.0 5.8 21.5 17.9 9.6 17.9 16.5 10.4 6.1 11.6 17.3 17.7 31.9 15.9 8.2 14.2 5.1 15.5 8.2 24.8 12.9 11.8 21.5 6.5 26.4 7.9 6.0 16.0 27.1 7.4 16.0 7.5 17.6 7.9 10.3 18.1 28.0 18.1 4.4 26.7 11.9 18.1 8.2 21.1 15.0 7.0 32.9 9.3 11.6 51.0 38.0 11.7 17.2 28.6 9.7 16.4 7.5 14.9 ST13 "FAM10A1, HIP, HSPABP1, P48, SNC6" ENSG00000100380 "ST13 Hsp70 interacting protein" P50502 22 40824535-40856639 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 1091.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043233, HPA046412, HPA047114, HPA047116" Enhanced Enhanced Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA043233: AB_2678377, HPA046412: AB_2679658, HPA047114: AB_2679937, HPA047116: AB_2679939" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.69e-2)" "unprognostic (7.15e-2)" "unprognostic (2.68e-2)" "prognostic unfavorable (5.23e-4)" "unprognostic (2.73e-3)" "unprognostic (1.74e-2)" "unprognostic (3.63e-1)" "unprognostic (2.50e-1)" "unprognostic (1.00e-1)" "unprognostic (9.54e-2)" "prognostic favorable (3.10e-4)" "unprognostic (8.41e-2)" "unprognostic (3.93e-2)" "unprognostic (3.04e-1)" "unprognostic (8.40e-2)" 163.2 157.5 131.9 84.2 148.3 99.0 161.6 149.9 171.9 163.0 140.4 135.6 96.7 197.5 137.2 116.6 180.6 122.8 121.9 123.8 156.8 254.2 296.7 97.0 111.7 147.3 140.5 542.6 126.2 150.8 92.3 135.3 154.8 145.0 108.0 146.4 111.3 142.6 341.2 98.4 108.3 165.0 147.2 89.0 111.1 107.7 136.1 131.6 176.6 217.9 126.2 131.5 113.5 191.9 249.0 195.1 290.6 255.4 265.7 407.1 263.7 229.0 293.2 279.6 242.3 353.7 144.3 356.8 193.2 232.9 253.7 177.3 387.7 226.3 331.2 228.4 250.3 255.0 379.1 406.4 241.2 374.6 198.5 365.5 235.7 252.6 169.7 351.2 293.6 219.3 313.2 151.2 271.3 187.1 329.5 200.1 166.4 302.0 130.7 375.7 246.4 281.9 284.2 369.8 96.4 97.1 265.0 211.7 337.7 334.1 205.5 233.2 220.8 232.1 223.0 197.0 188.2 173.5 367.9 333.4 317.4 172.0 228.2 108.9 79.5 85.7 84.7 108.7 129.1 146.2 133.0 101.9 107.1 131.6 206.6 160.7 26.3 110.6 146.3 75.5 122.3 162.6 131.9 148.3 149.9 171.9 123.8 156.8 147.3 140.5 154.8 147.2 136.1 191.9 187.0 141.1 220.5 28.1 217.5 311.6 384.6 267.7 279.4 89.5 364.6 359.2 140.1 334.6 232.5 171.0 16.7 382.8 141.7 192.9 563.4 284.8 513.2 431.6 349.8 204.1 262.0 296.3 37.4 205.1 381.2 239.7 107.0 289.6 207.1 305.0 227.7 539.2 328.6 38.7 41.5 263.7 183.1 270.6 374.5 1010.4 510.4 210.3 211.7 15.0 286.7 265.1 157.6 27.2 53.7 193.7 210.8 413.3 129.0 312.2 369.6 1091.8 281.8 73.0 223.5 212.0 268.7 306.9 191.2 193.5 274.5 500.9 200.6 227.3 333.2 325.8 XPNPEP3 "APP3, ICP55, NPHPL1" ENSG00000196236 "X-prolyl aminopeptidase 3" Q9NQH7 22 40857077-40932815 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 232.9;Late spermatids: 306.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000527 Approved Supported Mitochondria,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Mitochondria Cytosol "HPA000527: AB_1079266" "prognostic unfavorable (8.19e-4)" "unprognostic (6.77e-2)" "unprognostic (3.22e-3)" "unprognostic (5.03e-3)" "unprognostic (6.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-1)" "unprognostic (2.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.49e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.24e-1)" 2.7 4.9 6.4 1.3 6.3 1.6 2.6 8.3 7.8 2.9 7.1 2.5 14.6 4.7 5.0 2.8 3.7 4.4 5.3 7.8 6.1 3.7 8.2 2.4 2.5 7.2 6.6 3.8 3.6 2.1 3.7 1.5 6.6 2.8 2.2 4.4 3.4 2.5 5.5 5.5 10.1 2.4 5.6 2.8 2.8 3.7 6.7 5.9 3.2 3.5 1.9 3.7 2.8 9.0 2.7 4.1 2.5 5.5 6.3 4.6 2.1 3.3 2.5 1.7 1.7 3.1 1.6 5.2 1.8 6.5 7.8 7.3 4.7 2.4 2.7 3.5 9.7 3.3 9.7 7.5 3.2 6.0 0.5 4.0 3.9 5.7 3.3 2.7 3.3 3.8 2.9 4.8 4.3 4.1 3.1 3.2 1.5 5.0 8.3 3.9 3.3 3.0 5.9 3.6 2.3 1.9 3.9 4.8 3.3 2.6 6.1 2.7 3.2 3.6 3.4 3.4 2.1 4.7 4.0 7.4 5.6 8.5 2.5 2.8 2.5 2.9 2.1 2.5 1.0 3.7 1.2 1.2 1.9 1.9 2.4 1.9 3.6 0.7 6.9 3.8 1.9 2.8 6.4 6.3 8.3 7.8 7.8 6.1 7.2 6.6 6.6 5.6 6.7 9.0 9.6 6.4 17.6 32.0 12.7 13.3 8.0 15.6 9.6 16.0 12.9 13.2 22.5 15.7 14.0 9.2 18.8 21.7 11.0 6.2 15.6 12.2 232.9 37.5 16.6 11.7 13.8 12.0 22.0 17.1 18.7 13.1 12.2 12.0 14.0 17.8 10.8 36.0 14.7 16.8 24.0 9.5 12.2 12.6 15.7 306.8 19.9 11.9 17.8 18.7 7.8 13.0 9.2 19.6 42.3 10.4 9.5 15.4 11.8 7.8 3.5 25.3 38.5 19.8 32.9 14.0 12.7 65.6 34.2 12.2 16.3 20.0 11.0 19.5 8.7 7.6 DNAJB7 HSC3 ENSG00000172404 "DnaJ heat shock protein family (Hsp40) member B7" Q7Z6W7 22 40859549-40862113 "Predicted intracellular proteins" Chaperone "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 12 "testis: 10.4" "Cell type enriched" "Detected in some" 5 "Early spermatids: 553.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA000534 Approved NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "HPA000534: AB_1078693" "unprognostic (3.89e-2)" "unprognostic (1.12e-2)" "unprognostic (9.61e-2)" "unprognostic (1.27e-1)" "unprognostic (5.45e-2)" "unprognostic (2.66e-2)" "unprognostic (1.16e-2)" "unprognostic (5.56e-3)" "unprognostic (1.62e-1)" "unprognostic (7.42e-2)" "unprognostic (1.22e-3)" "unprognostic (2.81e-2)" "unprognostic (4.46e-4)" "unprognostic (3.32e-3)" "unprognostic (3.06e-2)" "unprognostic (7.05e-2)" "unprognostic (2.45e-2)" 0.1 0.1 0.1 0.1 0.2 0.5 0.1 0.8 0.7 0.2 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.8 0.2 0.0 0.4 0.1 0.5 0.0 0.0 0.1 0.1 10.4 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.1 0.4 0.4 0.2 0.1 0.0 0.2 0.2 0.1 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.7 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 4.2 0.1 0.4 0.8 0.0 0.0 553.5 1.5 0.8 0.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.4 4.5 0.2 0.0 0.0 0.1 1.7 0.5 0.4 0.0 0.0 0.0 98.5 2.8 0.2 0.0 0.0 0.0 0.9 0.0 1.0 0.7 0.0 0.0 2.6 0.1 0.1 6.0 0.0 0.0 11.2 0.0 0.3 0.1 2.9 1.5 0.0 0.0 0.3 0.2 0.2 0.9 0.1 RBX1 "BA554C12.1, RNF75, ROC1" ENSG00000100387 "Ring-box 1" P62877 22 40951347-40973309 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003038 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "HPA003038: AB_1079827" "unprognostic (2.34e-1)" "unprognostic (1.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.60e-3)" "unprognostic (2.30e-1)" "unprognostic (2.92e-2)" "unprognostic (1.82e-3)" "unprognostic (1.74e-1)" "unprognostic (6.61e-2)" "prognostic favorable (6.63e-4)" "unprognostic (5.01e-3)" "unprognostic (2.19e-1)" "unprognostic (4.99e-3)" "unprognostic (2.22e-2)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" "unprognostic (3.05e-2)" 37.8 46.8 82.3 33.4 85.6 63.4 45.1 88.4 105.1 38.5 79.7 36.6 26.3 34.3 59.2 53.5 31.4 22.3 72.7 82.9 86.5 49.4 38.9 37.5 44.5 88.2 84.1 26.9 24.7 38.3 34.5 40.9 87.3 32.8 32.8 45.3 33.1 26.9 83.2 43.3 33.1 32.7 89.7 39.8 37.5 24.8 84.1 59.3 35.8 100.5 51.6 36.4 37.7 93.6 111.1 62.2 114.4 57.9 79.9 94.9 64.3 86.6 80.0 128.2 112.9 101.4 52.5 96.7 57.3 86.3 50.8 62.3 110.6 100.2 135.1 113.9 174.7 60.4 84.0 126.1 68.2 148.3 74.8 79.1 79.1 93.0 66.6 73.3 110.5 57.8 72.2 95.6 115.1 136.7 90.2 170.1 63.7 216.3 64.8 116.8 80.0 122.5 149.3 71.0 54.1 34.9 76.5 76.3 82.7 63.8 65.8 99.5 74.8 77.9 81.1 66.4 84.5 80.0 78.9 146.5 98.0 74.7 88.6 151.8 128.1 108.7 79.9 133.9 76.0 114.7 99.2 85.7 129.7 102.4 85.5 93.8 42.3 89.2 154.6 211.1 137.6 250.2 82.3 85.6 88.4 105.1 82.9 86.5 88.2 84.1 87.3 89.7 84.1 93.6 224.9 230.8 144.8 23.5 173.6 300.9 207.2 567.7 129.1 90.4 189.6 237.9 515.4 171.6 300.0 224.3 25.0 507.3 238.6 181.8 508.7 346.8 41.1 227.4 170.6 222.1 162.1 638.3 29.9 333.6 637.9 211.2 107.6 180.4 129.8 140.0 167.4 254.8 431.3 89.2 29.7 205.1 349.9 236.7 334.2 79.4 185.8 270.7 341.5 15.0 532.3 264.5 228.6 18.6 49.6 377.7 229.8 177.1 180.8 269.5 300.5 586.5 314.3 163.7 118.3 160.0 256.3 220.2 242.9 237.5 370.7 675.9 175.3 185.7 207.1 248.8 EP300 "KAT3B, p300" ENSG00000100393 "E1A binding protein p300" Q09472 22 41092592-41180077 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000146, HPA003128, HPA004112" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB000146: AB_2533138, HPA003128: AB_1078745, HPA004112: AB_1078746" "unprognostic (7.67e-2)" "unprognostic (5.56e-2)" "unprognostic (2.29e-1)" "unprognostic (2.52e-1)" "unprognostic (6.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.21e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (8.97e-2)" "unprognostic (1.74e-2)" "unprognostic (8.54e-2)" "prognostic favorable (7.45e-5)" "unprognostic (7.97e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" 15.7 13.7 6.8 17.7 8.9 65.1 14.2 20.5 10.8 16.0 6.1 16.6 13.6 17.2 13.5 16.3 16.4 14.2 11.5 7.1 9.4 13.1 15.5 14.7 17.6 10.6 7.8 23.9 18.0 23.2 13.4 19.3 7.7 15.0 14.5 17.8 15.0 15.6 20.4 18.9 16.0 16.4 5.3 17.0 14.5 19.6 8.6 27.2 20.2 23.4 17.9 15.4 14.8 11.2 31.6 21.7 35.4 23.0 22.2 23.3 32.3 15.0 21.8 21.0 21.0 27.8 12.0 32.7 12.2 28.4 18.7 24.1 48.1 20.8 23.5 30.5 32.2 24.4 25.4 22.3 26.9 59.3 26.5 24.8 22.2 30.0 27.0 19.3 24.9 18.7 26.3 43.9 18.3 12.5 16.2 18.9 27.5 38.3 15.2 33.7 16.7 21.3 20.3 40.4 11.3 11.9 51.1 26.0 25.6 29.5 17.8 33.9 31.3 20.3 24.8 16.3 20.8 28.5 14.1 47.9 16.3 17.4 21.5 3.6 1.7 1.6 1.6 1.9 1.5 2.2 1.7 1.7 2.1 1.4 1.4 1.1 4.9 2.7 1.0 1.6 1.4 1.2 6.8 8.9 20.5 10.8 7.1 9.4 10.6 7.8 7.7 5.3 8.6 11.2 45.4 67.3 49.2 58.1 53.8 24.6 22.9 11.6 40.9 44.6 35.1 25.8 31.6 38.6 15.8 25.8 35.5 18.4 63.2 37.0 3.9 16.1 15.3 55.1 56.4 36.2 24.7 60.4 71.8 18.7 17.9 32.0 27.5 72.5 25.3 36.1 32.9 29.2 18.4 25.2 73.6 24.2 2.0 60.7 25.7 6.4 28.9 60.5 8.8 45.9 52.0 27.7 40.2 81.4 80.3 25.8 28.9 30.5 51.2 30.8 20.2 10.8 22.8 30.9 26.3 47.6 36.7 22.8 31.2 35.3 25.9 30.2 46.0 36.7 23.7 36.3 L3MBTL2 "dJ756G23.3, DKFZP761I141, H-l(3)mbt-l" ENSG00000100395 "L3MBTL histone methyl-lysine binding protein 2" Q969R5 22 41205282-41231271 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000815 Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "HPA000815: AB_1079220" "unprognostic (2.42e-1)" "prognostic favorable (6.39e-5)" "unprognostic (3.98e-2)" "prognostic favorable (4.37e-4)" "unprognostic (3.48e-1)" "unprognostic (1.19e-2)" "unprognostic (4.16e-3)" "unprognostic (1.03e-2)" "unprognostic (2.19e-1)" "unprognostic (2.26e-1)" "unprognostic (7.95e-3)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.07e-3)" "unprognostic (1.81e-1)" "unprognostic (2.70e-2)" "unprognostic (2.19e-1)" 9.8 14.6 15.8 12.3 16.6 11.0 10.5 14.7 16.8 12.8 12.6 13.5 8.6 13.2 12.1 12.1 19.4 9.5 13.2 15.4 16.3 14.2 16.6 11.8 17.7 16.3 16.4 14.0 11.0 17.0 16.4 9.5 17.0 14.2 10.2 10.0 13.0 13.8 11.9 13.7 11.6 13.9 14.7 15.5 12.7 14.9 16.6 15.0 12.2 9.0 18.0 13.9 10.4 24.3 21.3 20.8 17.6 35.6 20.9 15.6 20.6 19.8 22.7 37.7 31.1 13.7 15.0 34.6 15.7 26.7 22.6 20.3 40.9 26.3 23.9 42.3 52.8 14.4 35.7 32.9 22.1 65.8 31.4 21.4 10.2 29.6 27.8 16.4 27.2 26.1 24.9 27.5 18.1 37.4 33.4 22.4 23.9 75.6 23.8 34.1 14.3 39.9 19.0 20.9 14.3 10.0 35.5 25.3 21.4 17.0 16.9 36.0 21.6 20.2 19.1 16.2 22.2 22.6 43.1 28.6 23.3 29.7 26.3 10.0 13.4 10.7 21.4 16.6 19.6 15.7 16.7 17.1 17.0 11.0 20.0 18.9 2.1 21.2 18.6 12.9 18.4 21.6 15.8 16.6 14.7 16.8 15.4 16.3 16.3 16.4 17.0 14.7 16.6 24.3 9.4 16.0 19.6 7.5 12.2 2.7 5.1 8.0 2.8 24.7 9.0 8.9 10.2 15.7 17.1 11.0 16.7 17.7 15.8 9.6 11.7 9.9 13.9 14.8 9.1 9.3 15.0 10.5 9.9 7.9 17.4 9.3 13.7 8.0 11.4 12.0 7.9 14.2 13.0 16.8 10.8 8.7 22.4 11.1 4.6 30.0 7.2 11.6 3.6 3.7 11.2 13.7 12.3 9.5 8.1 7.6 5.8 9.4 13.3 6.9 7.3 8.7 22.6 15.0 6.6 9.4 13.4 21.5 14.4 6.7 3.8 17.1 13.9 17.5 9.4 6.2 CHADL SLRR4B ENSG00000100399 "Chondroadherin like" Q6NUI6 22 41229510-41240931 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 109.6" "Cell type enhanced" "Detected in many" "Muller glia cells: 40.3;Oligodendrocytes: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 11.8;Hep G2: 3.4;hTCEpi: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005696, HPA024654" Uncertain "Secreted to extracellular matrix" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "HPA005696: AB_1079724, HPA024654: AB_1846615" "unprognostic (6.14e-2)" "unprognostic (4.42e-3)" "unprognostic (1.49e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (9.51e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (2.83e-3)" "unprognostic (1.51e-2)" "unprognostic (4.67e-8)" "unprognostic (8.36e-3)" "unprognostic (4.10e-1)" "unprognostic (3.40e-1)" "unprognostic (4.09e-2)" 2.6 4.7 25.4 0.5 62.4 1.0 2.6 57.5 43.9 3.5 5.2 12.4 1.5 1.3 1.5 4.2 2.2 2.7 16.5 25.1 32.4 2.1 3.1 2.1 0.8 69.6 51.8 2.6 3.5 0.5 4.3 0.6 61.3 6.5 0.3 1.0 11.3 3.8 2.2 6.1 3.4 0.8 43.4 0.7 5.0 3.5 56.3 1.7 4.4 1.6 0.4 2.9 3.6 109.6 0.6 0.2 0.2 0.3 0.1 0.1 11.8 0.4 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.6 0.1 0.5 0.0 0.6 0.0 0.1 0.2 0.0 0.3 3.4 0.4 0.1 0.1 1.0 3.4 0.3 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.3 0.2 0.6 0.3 0.3 0.4 0.1 0.5 0.2 0.2 0.3 0.7 0.1 1.3 0.2 0.1 0.0 0.0 1.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.1 1.6 0.0 0.1 0.4 0.1 0.4 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.1 0.2 0.0 0.0 1.2 0.0 0.3 25.4 62.4 57.5 43.9 25.1 32.4 69.6 51.8 61.3 43.4 56.3 109.6 2.7 6.4 2.2 8.1 0.2 4.0 10.2 1.8 17.6 1.4 7.3 6.5 3.5 2.8 1.7 3.7 0.0 3.0 0.4 0.8 7.9 2.0 18.6 2.5 0.6 1.3 3.0 0.0 2.8 1.2 6.4 5.5 2.6 1.6 0.0 3.2 2.5 2.5 5.1 0.0 2.5 0.8 2.0 0.8 2.1 12.0 3.7 3.4 17.8 1.9 0.4 40.3 0.0 12.5 83.1 0.8 1.0 3.0 0.3 3.7 1.3 5.9 4.1 1.6 0.0 2.5 1.2 0.3 0.8 6.5 3.7 1.5 0.5 0.7 1.4 6.5 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 ZC3H7B "DKFZp434K0920, FLJ13787, KIAA1031, RoXaN" ENSG00000100403 "Zinc finger CCCH-type containing 7B" Q9UGR2 22 41301525-41360147 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001784, HPA076092" Uncertain Supported Cytosol NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Cytosol "HPA001784: AB_1080637, HPA076092: " "unprognostic (1.71e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-2)" "unprognostic (3.53e-2)" "unprognostic (3.35e-2)" "unprognostic (5.66e-2)" "unprognostic (3.73e-2)" "unprognostic (7.92e-2)" "unprognostic (7.12e-2)" "unprognostic (7.73e-2)" "unprognostic (1.39e-2)" "unprognostic (3.19e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.43e-2)" "unprognostic (2.92e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-1)" 29.5 42.9 37.5 20.2 37.1 16.0 22.9 31.9 43.4 25.6 15.1 25.8 24.3 31.1 13.5 20.3 27.2 17.2 26.1 34.1 38.7 31.4 42.1 26.9 21.4 56.0 35.7 41.3 30.9 44.5 30.5 18.5 58.8 26.0 13.2 17.9 44.9 26.7 24.9 20.0 25.9 20.7 30.2 25.6 24.8 11.6 37.2 25.2 45.9 19.1 15.2 23.5 19.7 36.0 59.0 32.2 42.0 25.6 37.6 33.9 49.1 65.8 69.6 53.8 42.1 35.3 23.8 33.1 79.1 92.0 30.1 39.1 35.7 61.8 27.4 76.0 58.9 29.6 40.2 45.4 50.4 57.4 24.9 42.7 34.6 46.3 56.4 45.7 58.9 25.7 60.4 17.9 46.0 59.1 45.4 29.7 30.3 44.2 24.1 68.7 26.4 37.8 45.9 41.5 27.1 20.3 60.5 36.6 31.5 29.0 24.1 38.1 119.0 52.5 54.4 16.3 40.8 30.8 18.4 33.2 44.0 28.0 46.1 0.0 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 37.5 37.1 31.9 43.4 34.1 38.7 56.0 35.7 58.8 30.2 37.2 36.0 15.4 12.8 22.2 14.4 13.1 7.1 12.7 13.4 10.2 22.4 18.2 15.6 10.1 20.0 15.7 22.0 18.8 9.0 11.3 13.5 7.9 14.0 0.9 14.2 25.8 17.9 33.6 7.8 20.1 13.3 9.0 16.4 11.2 16.9 8.2 59.0 19.2 44.0 12.0 42.1 20.6 14.6 26.4 12.9 9.8 3.1 33.2 8.2 12.4 13.1 15.2 9.8 20.6 19.1 17.6 18.8 8.1 29.0 7.4 21.2 23.0 18.5 11.7 22.2 19.7 23.1 18.0 2.0 4.9 8.9 5.8 6.2 11.1 46.9 17.1 14.8 TEF KIAA1655 ENSG00000167074 "TEF transcription factor, PAR bZIP family member" Q10587 22 41367333-41399326 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 31.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "unprognostic (6.75e-2)" "unprognostic (5.24e-2)" "unprognostic (1.27e-2)" "unprognostic (2.57e-3)" "unprognostic (1.75e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (3.91e-3)" "unprognostic (7.87e-2)" "unprognostic (6.82e-3)" "unprognostic (2.12e-2)" "unprognostic (7.17e-3)" "prognostic favorable (3.47e-11)" "unprognostic (7.54e-2)" "unprognostic (2.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.55e-2)" 15.6 14.3 29.7 5.2 41.8 0.8 12.8 43.7 51.4 14.9 5.4 20.1 8.0 16.0 10.3 14.9 18.7 8.2 32.4 40.3 13.9 19.1 18.6 14.4 7.8 21.3 16.9 35.5 23.2 46.8 21.2 4.4 21.8 13.9 10.9 25.5 29.0 24.1 44.0 25.6 11.0 9.6 9.2 11.0 13.3 12.1 21.8 9.1 28.7 39.9 8.3 15.1 11.9 35.5 4.5 2.1 6.9 8.0 11.4 6.7 5.0 3.3 16.1 4.6 6.4 5.9 11.1 12.7 4.7 16.6 6.8 9.5 2.1 7.8 5.3 5.8 3.2 2.6 4.3 3.8 5.0 3.9 3.6 9.4 12.5 6.0 14.0 11.1 3.2 2.7 1.2 10.7 2.3 10.5 3.3 2.8 4.0 31.1 5.2 9.3 4.4 5.5 3.5 9.9 6.5 3.3 15.0 3.3 6.8 5.6 5.5 4.4 4.8 12.7 13.6 5.2 5.3 11.0 8.5 8.1 12.4 3.4 13.7 0.0 0.2 0.8 0.6 0.7 0.9 0.4 0.6 0.6 0.2 0.1 0.7 0.5 0.4 0.1 0.4 0.8 0.5 0.3 29.7 41.8 43.7 51.4 40.3 13.9 21.3 16.9 21.8 9.2 21.8 35.5 9.8 16.0 9.9 21.2 1.3 6.6 3.2 4.9 12.5 41.9 4.3 6.9 13.1 20.0 3.3 18.4 8.4 4.4 0.7 18.7 11.7 3.4 11.3 1.3 5.6 7.0 7.7 0.4 14.2 6.1 0.6 13.2 3.6 1.7 4.5 6.5 6.4 33.4 1.3 32.0 15.0 6.0 8.2 4.1 4.0 23.2 17.1 1.7 5.4 1.9 2.3 27.3 2.1 9.0 17.4 3.9 4.4 25.6 1.2 3.6 11.2 5.6 5.5 13.7 6.6 19.6 9.0 3.7 5.7 6.7 8.7 1.4 1.9 9.1 4.6 2.4 TOB2 "APRO5, bK223H9, TOB4, TOBL, TROB2" ENSG00000183864 "Transducer of ERBB2, 2" Q14106 22 41433494-41446801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016603, HPA054112" Approved Approved Cytosol NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "HPA016603: AB_2669400, HPA054112: AB_2682385" "unprognostic (1.21e-3)" "unprognostic (3.10e-2)" "unprognostic (3.41e-1)" "prognostic favorable (3.08e-5)" "unprognostic (3.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (5.74e-2)" "unprognostic (3.18e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.18e-6)" "unprognostic (1.50e-2)" "unprognostic (7.14e-2)" "unprognostic (1.85e-1)" "unprognostic (7.13e-2)" 46.1 31.3 39.3 15.6 56.3 9.7 25.5 78.1 40.1 26.5 18.5 30.1 22.4 25.0 11.8 26.6 38.4 28.8 41.2 39.3 43.8 24.6 27.1 20.7 18.5 61.7 42.9 38.0 29.0 35.6 22.8 22.0 44.0 26.6 15.5 55.0 17.2 19.4 86.5 27.1 23.9 20.1 39.5 20.6 30.5 13.6 52.0 19.6 36.1 68.1 19.7 23.3 21.0 71.9 36.8 16.6 28.5 19.4 65.4 45.5 27.5 23.9 36.7 29.8 26.2 21.9 17.0 22.4 23.5 34.8 11.6 31.4 26.7 13.4 27.1 23.0 34.2 12.3 23.9 33.4 44.8 33.5 15.9 42.1 22.5 35.6 15.4 30.1 30.2 7.6 18.9 24.5 24.6 40.8 13.9 19.2 24.4 48.1 17.6 29.7 19.2 19.4 21.3 25.3 13.1 8.8 60.0 32.2 44.6 17.7 17.9 16.5 37.9 29.3 27.1 23.0 22.7 22.9 10.7 12.2 17.8 14.2 19.7 3.9 5.9 4.1 7.5 8.0 7.1 10.0 6.2 6.3 5.3 7.5 3.2 4.7 3.8 3.8 8.4 8.0 5.5 6.1 39.3 56.3 78.1 40.1 39.3 43.8 61.7 42.9 44.0 39.5 52.0 71.9 48.5 48.1 59.6 48.6 61.4 126.8 66.6 24.3 105.3 56.0 83.1 56.9 59.8 58.6 31.7 47.8 64.6 34.7 56.9 76.9 23.5 29.7 41.1 88.6 59.3 45.3 54.3 16.8 12.2 19.1 37.3 54.1 42.3 116.9 34.1 13.7 52.5 29.7 19.6 25.2 15.1 67.7 10.2 22.0 117.9 61.6 66.8 51.4 53.4 14.0 34.6 58.3 18.6 10.1 43.6 32.3 60.0 82.0 26.2 73.6 103.6 29.2 45.9 105.2 52.6 97.4 60.9 23.8 28.9 88.7 136.7 63.3 57.4 19.6 61.9 92.2 ACO2 ACONM ENSG00000100412 "Aconitase 2" Q99798 22 41447830-41529273 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Lyase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 567.7;skeletal muscle: 660.4;tongue: 695.8" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 374.2;Proximal tubular cells: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001097 Enhanced Approved Approved Mitochondria NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA001097: AB_1078092" "unprognostic (1.95e-1)" "unprognostic (2.50e-2)" "unprognostic (2.35e-2)" "unprognostic (3.06e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-1)" "unprognostic (3.99e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-2)" "unprognostic (7.32e-2)" "unprognostic (1.64e-2)" "unprognostic (6.07e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.46e-2)" "unprognostic (9.60e-2)" "unprognostic (6.45e-2)" "unprognostic (1.12e-2)" 88.8 81.6 154.2 38.6 152.2 32.0 52.4 153.0 190.0 39.5 160.1 94.4 162.9 42.0 26.1 60.4 53.6 36.5 567.7 155.2 153.1 138.9 73.9 40.7 40.5 146.1 145.3 30.8 53.8 233.8 33.6 30.5 147.8 41.2 69.6 46.9 72.0 49.5 660.4 45.5 158.5 43.7 152.5 44.7 110.2 35.1 186.3 38.0 53.7 695.8 43.3 52.5 42.4 159.6 47.2 55.8 56.5 116.3 101.2 69.8 78.7 43.7 60.9 79.0 71.9 81.2 63.5 115.7 72.2 70.6 60.3 109.8 108.8 88.3 42.8 75.8 80.2 51.0 73.7 95.0 86.7 147.8 77.8 120.8 64.4 78.9 83.2 61.7 81.2 61.5 72.9 118.4 65.4 91.7 73.7 47.9 37.0 282.6 115.1 102.3 37.8 162.1 106.8 97.3 37.8 33.9 112.2 128.7 82.0 44.9 74.9 74.7 55.5 60.0 68.7 50.2 45.0 64.7 92.1 80.6 102.0 64.0 66.5 10.3 52.9 18.1 32.0 76.4 29.3 49.4 25.5 34.9 69.0 46.4 29.2 30.8 9.0 39.4 97.1 24.0 41.2 58.6 154.2 152.2 153.0 190.0 155.2 153.1 146.1 145.3 147.8 152.5 186.3 159.6 26.3 25.6 31.8 45.4 49.4 18.7 54.5 102.7 31.3 60.6 28.0 23.2 9.1 64.3 63.5 60.7 81.3 100.3 33.3 190.8 131.0 58.3 14.5 37.2 17.7 26.1 53.2 30.3 28.8 42.6 60.0 24.0 77.5 37.1 40.6 56.7 20.7 64.6 91.5 53.8 34.0 99.1 89.5 35.5 26.4 8.9 24.2 39.2 35.6 7.5 68.3 73.9 34.0 12.1 20.9 43.9 103.5 27.8 63.2 34.4 374.2 285.7 59.2 73.5 59.2 28.6 38.4 26.4 38.2 35.8 16.1 193.2 30.7 54.4 113.6 64.9 PHF5A "bK223H9.2, INI, MGC1346, Rds3, SAP14b, SF3b14b, SF3B7" ENSG00000100410 "PHD finger protein 5A" Q7RTV0 22 41459717-41468692 "Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028885 Supported Enhanced Nucleoplasm NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA028885: AB_10602079" "unprognostic (4.38e-2)" "unprognostic (3.58e-1)" "unprognostic (2.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-1)" "unprognostic (2.10e-2)" "prognostic unfavorable (3.02e-8)" "unprognostic (3.39e-3)" "unprognostic (3.97e-3)" "unprognostic (4.46e-2)" "unprognostic (6.95e-3)" "unprognostic (2.12e-1)" "unprognostic (5.25e-3)" "unprognostic (4.11e-2)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "unprognostic (6.91e-2)" 26.0 21.1 26.5 23.0 29.7 58.2 27.7 30.0 30.6 23.3 28.9 25.1 22.7 22.9 26.0 29.0 22.8 19.6 20.9 26.7 28.5 25.5 30.9 20.1 35.5 28.9 28.5 20.7 26.2 25.1 21.5 25.6 29.7 19.7 28.8 24.5 21.0 19.1 35.8 27.7 22.4 22.6 28.8 26.4 26.0 18.8 28.2 52.2 19.7 29.0 41.9 30.6 23.7 33.9 80.5 56.8 95.0 62.8 68.7 51.7 65.9 80.1 65.5 102.9 86.4 78.4 46.5 115.4 45.7 60.1 72.1 60.7 130.2 95.3 115.6 71.7 136.5 71.8 86.9 92.2 71.9 190.3 54.9 50.4 72.9 81.3 100.5 41.7 73.8 80.6 97.5 71.8 74.9 107.5 154.8 124.3 96.1 220.8 82.2 115.4 84.9 81.5 68.6 63.1 46.6 38.9 87.9 57.4 90.0 66.6 45.9 96.8 50.7 54.0 95.6 44.1 97.9 58.9 112.3 194.9 52.2 82.6 59.0 32.8 47.0 57.9 36.0 45.2 47.2 47.6 41.1 45.6 49.2 42.6 40.2 39.5 55.6 47.6 44.1 41.7 47.8 59.3 26.5 29.7 30.0 30.6 26.7 28.5 28.9 28.5 29.7 28.8 28.2 33.9 36.4 22.4 13.9 2.3 52.3 77.2 78.1 81.1 58.1 24.6 35.1 35.4 10.6 41.5 33.5 11.0 4.2 93.0 42.3 27.2 46.9 58.5 14.7 26.6 20.7 43.7 15.0 56.1 3.5 56.2 115.0 36.2 20.4 25.5 33.7 20.9 37.5 24.7 58.7 13.5 3.7 32.1 63.1 38.8 55.9 9.1 42.3 37.3 33.8 2.8 67.5 47.3 59.8 5.5 8.2 64.5 32.5 41.8 41.6 84.4 41.1 42.1 24.3 28.2 98.6 32.3 38.6 63.5 88.1 59.0 91.6 109.2 42.3 20.2 41.9 95.7 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 CSDC2 PIPPin ENSG00000172346 "Cold shock domain containing C2" Q9Y534 22 41561010-41577741 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 143.8;heart muscle: 288.2;ovary: 133.6" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 75.0;Distal tubular cells: 19.6;Granulosa cells: 30.7;Muller glia cells: 51.7;Proximal tubular cells: 42.5;Sertoli cells: 72.3;Smooth muscle cells: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 12.4;U-2 OS: 41.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003073, HPA076549" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 9: U-2 OS - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Cytosol "HPA003073: AB_1078578, HPA076549: AB_2686807" "unprognostic (9.42e-2)" "unprognostic (5.52e-2)" "unprognostic (3.66e-3)" "unprognostic (1.36e-1)" "unprognostic (2.06e-1)" "unprognostic (3.52e-1)" "unprognostic (3.93e-2)" "unprognostic (1.60e-1)" "unprognostic (2.70e-3)" "unprognostic (2.35e-2)" "unprognostic (1.93e-1)" "unprognostic (3.72e-1)" "prognostic favorable (6.42e-4)" "unprognostic (8.86e-3)" "unprognostic (6.08e-2)" "unprognostic (1.02e-1)" "unprognostic (9.09e-3)" 6.8 143.8 29.4 1.6 21.8 0.1 3.2 64.5 32.1 69.9 4.1 16.5 0.8 83.5 1.4 3.2 24.1 2.3 288.2 30.5 35.3 40.4 2.6 11.5 0.2 44.4 41.0 133.6 51.1 0.0 20.5 0.4 36.9 26.2 0.5 5.2 1.0 10.4 2.7 2.1 3.2 10.9 26.1 1.1 4.5 31.3 44.9 0.0 2.5 2.7 0.0 27.4 29.0 22.7 0.0 0.2 1.5 0.2 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.9 0.0 0.0 0.5 4.7 0.5 0.1 0.0 0.0 0.0 0.0 2.9 0.0 12.4 1.5 3.5 0.0 0.0 1.9 0.1 0.0 0.0 3.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.6 0.0 0.3 0.1 1.1 0.2 0.0 0.1 0.1 1.0 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.1 41.8 0.3 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 29.4 21.8 64.5 32.1 30.5 35.3 44.4 41.0 36.9 26.1 44.9 22.7 0.1 0.0 0.0 4.6 0.5 0.3 0.2 0.3 0.6 9.9 0.1 0.6 75.0 0.0 0.0 7.3 2.1 0.1 0.0 0.0 19.6 0.3 1.5 0.2 6.0 0.9 0.0 0.0 6.8 10.4 0.1 5.1 0.0 0.1 0.0 30.7 0.4 0.2 0.2 6.7 11.0 0.0 0.0 0.0 0.0 5.1 5.3 0.3 1.8 0.0 0.0 51.7 0.0 1.0 0.6 2.4 0.0 2.6 0.0 0.2 0.0 42.5 0.7 3.2 72.3 0.4 19.9 2.1 0.3 0.0 0.1 0.3 0.2 0.3 0.0 0.0 PMM1 Sec53 ENSG00000100417 "Phosphomannomutase 1" Q92871 22 41576900-41589871 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030712, HPA074950" Uncertain Supported Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 45: Enterocytes - Digestion" Cytosol "HPA030712: AB_10669600, HPA074950: " "unprognostic (2.66e-1)" "prognostic favorable (5.92e-4)" "unprognostic (3.25e-2)" "prognostic favorable (6.09e-6)" "unprognostic (1.25e-1)" "unprognostic (2.85e-2)" "unprognostic (1.01e-2)" "unprognostic (1.95e-2)" "unprognostic (2.24e-3)" "unprognostic (1.78e-1)" "prognostic favorable (2.05e-4)" "unprognostic (6.56e-3)" "unprognostic (5.76e-3)" "unprognostic (2.78e-2)" "unprognostic (1.72e-1)" "unprognostic (1.40e-2)" "unprognostic (2.70e-1)" 47.0 51.7 49.0 12.0 50.4 26.2 39.0 47.0 65.0 34.4 41.2 33.6 37.7 26.9 19.2 73.7 34.7 18.8 26.5 49.5 52.1 59.4 64.2 33.8 17.5 46.9 47.2 48.1 45.0 15.4 19.5 14.2 51.2 26.5 20.3 13.6 23.3 20.2 16.2 33.2 33.8 19.9 47.8 13.7 65.7 32.6 49.8 14.3 13.8 11.4 16.8 31.7 28.0 49.7 16.0 29.0 19.6 42.5 54.3 84.0 23.0 61.7 69.8 56.0 61.0 23.0 15.3 14.9 20.3 74.4 40.0 23.4 25.8 40.0 31.1 31.2 38.6 3.8 34.8 49.2 85.8 22.6 23.8 70.4 38.2 58.3 24.2 61.9 9.3 23.8 16.9 51.9 76.5 42.0 17.1 32.5 6.2 75.1 38.2 13.1 20.7 30.7 24.0 17.1 5.8 11.2 50.5 18.1 75.2 15.2 20.3 24.4 7.5 63.2 34.3 59.4 32.8 33.2 34.0 24.3 70.3 18.8 38.7 21.0 22.0 44.8 27.7 18.5 22.3 17.8 27.6 22.8 23.2 20.5 29.4 21.1 28.8 13.4 22.9 9.2 49.4 18.8 49.0 50.4 47.0 65.0 49.5 52.1 46.9 47.2 51.2 47.8 49.8 49.7 7.8 35.3 106.4 16.3 15.0 14.8 10.2 22.5 20.5 16.7 22.8 29.3 12.4 82.9 25.8 35.0 6.2 57.1 10.0 104.8 107.6 31.8 17.1 77.7 34.2 6.9 48.7 19.3 14.9 11.0 91.1 33.3 36.2 51.4 3.8 60.9 8.9 83.5 34.5 28.6 10.9 58.1 14.2 14.4 13.5 15.3 28.0 16.3 44.4 3.7 21.9 67.1 16.5 4.0 7.1 10.8 117.0 30.5 17.7 8.5 176.1 138.5 34.8 22.6 39.5 18.9 36.9 72.6 10.9 23.1 14.1 65.3 21.0 37.9 55.3 8.2 DESI1 "D15Wsu75e, DESI-1, FAM152B, POST, PPPDE2" ENSG00000100418 "Desumoylating isopeptidase 1" Q6ICB0 22 41598028-41621043 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 761.4;Late spermatids: 415.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053415 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Cytokinetic bridge" "HPA053415: AB_2682141" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-2)" "prognostic favorable (7.70e-4)" "unprognostic (2.31e-2)" "unprognostic (6.16e-3)" "unprognostic (8.75e-3)" "unprognostic (9.27e-2)" "unprognostic (3.97e-2)" "unprognostic (6.27e-2)" "unprognostic (1.80e-2)" "unprognostic (1.42e-1)" "unprognostic (2.31e-3)" "unprognostic (2.65e-2)" "unprognostic (1.55e-1)" "unprognostic (8.18e-2)" "unprognostic (1.10e-1)" 11.9 18.5 34.3 10.4 36.0 7.5 10.9 37.1 36.6 10.7 23.6 13.3 11.6 11.2 11.3 26.4 10.2 8.9 38.1 34.4 37.5 22.3 47.3 14.7 11.6 36.1 37.9 12.4 12.5 13.1 12.2 9.3 35.5 13.0 10.6 12.9 12.0 10.6 16.1 15.5 12.6 11.3 34.9 13.5 16.4 18.7 38.6 8.8 9.2 17.6 13.6 12.7 11.9 35.3 16.7 17.4 17.0 23.4 23.5 28.0 9.6 33.0 21.0 30.0 21.9 23.2 10.4 63.2 22.2 38.2 15.7 23.8 45.7 36.8 31.1 28.6 34.7 14.2 32.5 19.7 28.8 56.4 18.4 24.1 42.2 36.8 34.1 24.3 45.8 21.7 42.0 69.5 24.0 21.2 12.9 17.2 16.8 62.2 26.0 17.3 7.2 65.2 38.0 10.5 12.1 6.3 31.8 34.5 23.0 19.3 11.4 18.3 46.8 22.0 16.0 23.4 16.3 25.4 21.1 29.7 54.4 24.4 29.7 9.1 6.6 7.8 3.3 9.0 4.3 4.1 4.0 3.9 5.2 3.7 3.5 4.3 3.8 2.1 6.2 3.0 5.3 4.2 34.3 36.0 37.1 36.6 34.4 37.5 36.1 37.9 35.5 34.9 38.6 35.3 21.2 9.6 18.9 10.7 27.1 8.7 36.6 42.1 13.1 19.8 29.7 29.8 55.2 18.6 21.7 9.2 6.2 31.1 15.0 29.0 39.2 50.8 761.4 29.5 24.7 24.1 19.7 11.8 13.9 30.2 39.5 17.6 19.4 55.0 10.8 27.6 19.6 72.9 50.4 21.9 18.1 19.9 22.4 28.1 18.6 415.8 19.0 33.8 14.2 6.5 49.4 18.6 30.9 11.6 13.3 50.0 29.5 10.5 46.5 111.0 80.1 53.7 10.8 11.4 26.3 14.3 24.3 149.4 30.7 43.6 13.2 83.6 22.4 28.9 26.3 72.3 XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 579.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 700000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "CAB004254: AB_628453, HPA047549: AB_2680085, HPA062226: AB_2684716" "unprognostic (5.55e-2)" "unprognostic (2.39e-2)" "unprognostic (1.82e-3)" "unprognostic (2.39e-1)" "unprognostic (2.47e-2)" "unprognostic (9.17e-2)" "unprognostic (1.16e-3)" "unprognostic (2.32e-2)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (1.33e-1)" "unprognostic (2.06e-3)" "unprognostic (1.22e-1)" "unprognostic (2.28e-1)" "unprognostic (4.77e-2)" "unprognostic (7.95e-2)" 143.7 183.4 84.9 153.4 89.3 218.2 143.3 87.8 100.8 152.1 87.2 159.5 136.8 153.8 111.3 192.1 151.4 105.5 176.1 89.2 94.7 136.9 142.4 133.2 196.6 89.5 86.8 169.8 119.0 156.5 122.6 155.0 92.2 132.7 164.9 115.6 130.8 144.4 273.0 168.3 142.8 161.0 93.5 143.1 138.6 231.2 87.9 224.1 137.8 184.3 222.2 162.6 142.0 96.4 554.6 388.0 527.9 455.5 313.5 279.5 413.8 394.7 464.6 794.9 656.4 570.4 335.7 886.2 319.8 478.1 357.4 400.6 739.2 486.8 803.2 493.4 921.2 478.8 435.2 559.5 281.5 1142.2 520.5 252.7 323.1 501.2 275.0 319.8 505.6 371.6 470.2 360.1 523.1 589.9 589.0 390.6 482.1 1138.4 452.1 660.0 562.3 695.6 440.4 404.4 243.3 174.6 644.1 328.2 455.7 392.9 382.2 439.0 366.2 394.3 546.2 354.0 522.4 354.0 671.9 896.1 369.4 441.3 476.4 146.0 264.3 227.6 243.6 296.5 258.4 256.5 269.5 269.2 324.1 246.9 293.2 262.5 69.2 253.2 307.0 191.7 325.9 600.8 84.9 89.3 87.8 100.8 89.2 94.7 89.5 86.8 92.2 93.5 87.9 96.4 96.6 96.1 142.5 18.6 132.6 124.0 201.0 219.0 83.1 107.1 80.1 83.4 89.4 115.8 160.4 82.8 62.6 422.3 104.9 97.3 166.3 205.4 119.6 86.1 87.0 117.0 98.6 125.4 24.5 182.7 317.2 123.9 73.4 105.9 119.7 156.4 70.3 103.7 170.2 87.5 29.5 114.7 166.8 98.1 116.7 62.9 126.8 110.4 88.9 17.8 182.8 149.7 89.6 26.2 30.5 150.9 106.6 126.7 116.0 112.0 113.7 140.3 112.6 103.6 164.3 102.4 127.4 579.8 314.4 91.5 102.1 362.2 136.9 150.6 166.8 137.5 SNU13 "15.5K, FA-1, NHP2L1, SNRNP15-5, SPAG12, SSFA1" ENSG00000100138 "Small nuclear ribonucleoprotein 13" P55769 22 41673933-41690504 "Predicted intracellular proteins, Ribosomal proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1057.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA029199 Uncertain NA NA 28000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 59: Non-specific - Transcription" "HPA029199: AB_10601041" "unprognostic (3.02e-1)" "unprognostic (4.82e-2)" "unprognostic (8.58e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-1)" "unprognostic (4.54e-2)" "unprognostic (1.94e-3)" "unprognostic (2.43e-1)" "unprognostic (6.65e-2)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (3.46e-2)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" "unprognostic (6.78e-2)" "unprognostic (1.43e-1)" 64.9 125.6 156.5 74.5 157.7 135.7 80.7 146.4 159.5 81.8 134.4 77.8 64.9 64.6 99.0 65.5 91.2 55.7 145.1 159.1 191.3 75.7 65.2 61.9 97.4 159.5 159.4 96.7 74.8 113.6 52.7 67.5 173.3 65.8 73.5 85.5 74.8 70.9 187.1 73.3 56.1 71.4 150.1 71.2 66.3 94.9 173.3 98.2 90.1 178.0 108.4 88.7 34.0 151.9 222.8 100.2 151.8 203.7 192.7 173.5 160.1 212.6 181.4 303.0 259.6 215.1 195.0 148.6 165.5 183.6 91.6 160.3 183.6 239.0 205.5 178.1 428.0 163.0 191.1 313.1 249.5 345.3 217.9 157.7 247.0 226.6 330.2 142.1 175.2 161.2 227.3 244.8 200.6 262.7 238.0 369.7 215.6 852.4 240.8 252.7 126.7 505.5 279.6 128.9 135.9 125.0 102.4 249.4 333.7 160.6 116.8 218.1 125.1 152.6 175.3 191.0 166.8 273.7 366.5 353.6 206.9 195.5 218.1 205.5 224.8 210.8 210.5 233.3 225.3 357.4 252.0 226.6 240.3 311.2 266.1 247.4 67.5 205.3 208.5 288.2 346.2 339.9 156.5 157.7 146.4 159.5 159.1 191.3 159.5 159.4 173.3 150.1 173.3 151.9 217.9 80.1 121.9 0.0 265.1 0.0 390.5 0.0 196.9 160.1 224.4 272.3 0.0 190.1 65.0 185.8 25.0 367.3 205.8 42.1 655.4 310.0 1057.6 223.4 169.0 198.0 70.4 144.7 0.0 302.3 438.5 172.4 125.4 251.9 77.0 162.3 181.3 205.0 293.1 109.4 0.0 118.9 0.0 140.1 0.0 318.4 211.9 162.9 0.0 0.0 186.3 181.8 151.4 0.0 0.0 340.9 127.7 174.2 261.9 630.5 202.2 462.5 68.5 128.4 138.1 169.0 143.0 505.9 279.5 219.8 0.0 460.5 208.0 193.8 139.5 505.0 MEI1 "MGC40042, SPATA38" ENSG00000167077 "Meiotic double-stranded break formation protein 1" Q5TIA1 22 41699503-41799456 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22.4;testis: 39.5" "Cell type enhanced" "Detected in many" "B-cells: 32.8;Early spermatids: 61.3;Late spermatids: 50.8;NK-cells: 29.9;Plasma cells: 94.7;Spermatocytes: 38.1;T-cells: 28.4" "Cancer enhanced" "Detected in many" "cervical cancer: 5.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HeLa: 11.6;HMC-1: 8.5;Karpas-707: 26.8;U-266/70: 29.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 7 "olfactory bulb: 1.4" HPA049240 Approved "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "HPA049240: AB_2680689" "unprognostic (1.95e-3)" "prognostic favorable (1.59e-6)" "unprognostic (6.13e-3)" "unprognostic (1.86e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-3)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-2)" "unprognostic (5.96e-2)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.45e-10)" "unprognostic (2.82e-1)" "unprognostic (3.02e-1)" "unprognostic (1.85e-1)" "unprognostic (7.39e-2)" 1.3 1.0 2.3 6.7 4.0 12.1 3.0 2.1 2.9 1.5 1.7 6.4 2.6 0.7 0.3 1.6 1.8 1.3 1.0 2.1 2.2 2.8 1.4 4.5 6.6 2.5 3.5 0.8 0.6 0.1 0.9 0.8 2.3 1.5 3.0 1.3 7.0 0.5 0.5 1.2 8.5 0.8 2.1 22.4 4.4 39.5 4.9 2.5 2.3 0.1 8.1 2.7 1.3 2.6 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 2.3 0.0 0.3 0.6 0.2 0.5 0.5 0.2 0.2 0.2 0.0 0.0 0.0 6.7 0.0 2.0 11.6 1.3 1.8 1.4 8.5 0.1 0.1 0.0 0.0 0.3 0.5 0.8 0.4 26.8 0.1 0.0 0.0 6.5 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 3.7 1.0 0.5 0.0 0.0 0.1 29.9 5.1 1.2 0.4 2.8 0.1 18.5 7.2 15.7 29.9 5.6 29.1 21.7 30.1 25.8 6.5 15.4 21.7 24.0 1.3 16.9 2.3 2.3 57.2 18.1 2.3 4.0 2.1 2.9 2.1 2.2 2.5 3.5 2.3 2.1 4.9 2.6 0.7 0.0 3.2 0.0 32.8 0.9 0.3 0.3 0.0 0.6 0.3 0.3 0.9 0.0 0.1 0.0 0.0 0.1 19.9 0.0 0.0 0.1 61.3 0.3 1.0 1.4 0.0 0.4 2.1 0.0 0.2 2.0 2.0 0.1 14.0 0.5 3.3 0.5 7.0 0.0 1.1 2.9 0.0 1.2 3.5 50.8 0.6 11.1 17.8 3.7 15.5 0.1 29.9 1.0 1.1 5.3 0.0 1.2 94.7 0.3 0.1 0.4 0.1 1.1 0.0 0.7 1.7 38.1 26.1 0.0 1.0 0.0 28.4 0.1 0.4 0.3 CCDC134 FLJ22349 ENSG00000100147 "Coiled-coil domain containing 134" Q9H6E4 22 41800679-41832164 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 18.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003936 Approved "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA003936: AB_1078419" "unprognostic (2.09e-2)" "unprognostic (1.00e-1)" "unprognostic (3.82e-2)" "prognostic favorable (4.09e-4)" "unprognostic (1.73e-1)" "unprognostic (3.85e-2)" "prognostic unfavorable (7.42e-7)" "unprognostic (4.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.08e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "prognostic favorable (1.36e-5)" "unprognostic (6.24e-3)" "unprognostic (2.52e-2)" "unprognostic (5.47e-1)" "unprognostic (6.63e-2)" 1.4 10.2 2.2 3.7 2.5 12.6 2.7 9.0 2.4 2.0 2.3 2.6 3.3 1.8 10.5 2.7 3.6 1.3 2.1 2.0 1.9 2.8 2.7 2.4 4.0 3.3 2.7 2.1 3.7 5.0 1.6 2.7 2.8 2.5 2.8 5.8 4.3 2.6 2.8 4.6 3.6 1.8 1.8 2.9 4.2 6.1 3.8 3.7 2.5 2.3 4.6 1.6 1.4 3.5 8.6 6.4 7.3 11.0 4.4 1.3 5.9 7.1 3.8 9.4 11.2 9.7 5.4 8.6 12.1 5.0 7.2 9.5 7.7 5.6 7.0 7.5 11.2 7.5 19.4 7.1 2.3 10.8 8.7 2.2 2.5 11.6 2.5 4.3 4.4 7.5 4.5 16.1 6.1 5.8 7.0 7.3 4.9 11.5 5.4 12.6 11.6 11.0 7.7 7.1 3.6 3.2 13.8 10.3 5.3 4.1 12.6 5.5 3.6 7.5 11.6 4.5 12.0 18.3 11.9 6.8 7.2 6.6 12.2 1.1 3.3 6.9 4.1 5.1 2.9 3.8 2.6 3.5 1.5 2.5 4.7 3.3 1.9 3.6 5.2 1.6 5.2 2.2 2.2 2.5 9.0 2.4 2.0 1.9 3.3 2.7 2.8 1.8 3.8 3.5 1.0 3.2 2.0 6.8 2.5 0.3 1.5 2.4 0.6 1.1 2.1 1.5 0.8 2.8 1.5 3.7 2.1 4.0 3.0 3.3 0.0 5.0 0.8 3.5 1.3 1.7 0.0 2.5 6.0 1.9 18.2 1.7 3.6 2.5 0.0 2.1 0.4 1.6 4.3 0.0 6.4 2.0 0.0 1.0 0.7 0.9 0.6 1.7 1.8 10.3 4.1 0.7 2.1 9.0 5.8 2.6 1.9 0.4 7.9 1.8 3.5 1.4 2.6 2.3 0.0 1.7 2.1 3.7 1.3 1.8 0.0 2.9 2.1 3.3 3.1 1.6 SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" 22.8 80.7 50.1 31.1 58.7 32.3 24.5 22.3 60.5 26.5 2.5 47.1 40.8 34.4 60.5 82.0 27.4 25.3 53.8 51.8 32.3 33.3 36.2 43.2 35.2 38.5 37.8 35.8 45.8 51.4 30.5 24.5 38.3 33.5 31.6 21.0 49.1 22.9 34.1 58.4 35.9 30.1 16.1 26.1 53.8 20.4 37.8 25.0 23.3 33.5 36.2 29.7 39.0 45.1 65.5 45.8 119.4 111.6 68.4 90.9 66.7 21.4 71.1 24.8 50.5 54.3 84.2 115.8 29.7 52.6 91.1 109.6 68.7 141.8 17.5 32.9 75.0 58.0 79.7 54.6 113.8 85.7 37.9 85.8 78.7 65.1 80.6 56.7 49.2 64.2 60.6 135.9 26.4 83.1 62.5 64.5 75.7 81.2 34.9 71.3 68.1 189.0 103.3 67.6 48.2 36.3 49.1 89.3 91.7 69.5 56.3 150.2 53.0 33.2 61.0 15.9 25.8 98.3 54.3 91.7 32.4 64.0 51.9 0.0 4.7 1.6 4.6 3.6 3.1 7.0 2.5 3.3 5.0 4.8 2.2 2.6 0.7 1.4 3.1 6.3 1.5 4.8 50.1 58.7 22.3 60.5 51.8 32.3 38.5 37.8 38.3 16.1 37.8 45.1 14.5 44.8 43.3 100.6 35.4 16.3 13.5 52.2 30.7 41.0 36.3 23.1 30.3 37.1 38.0 58.8 10.4 25.4 23.5 67.0 3.9 20.3 15.9 25.2 10.5 16.8 49.1 14.1 72.6 44.3 22.6 16.3 42.8 59.2 12.7 43.2 8.2 34.3 14.8 57.2 75.1 39.4 52.9 10.3 14.8 7.0 31.4 16.3 7.2 67.5 18.1 18.6 20.6 90.5 129.5 38.4 30.5 27.4 29.2 27.9 26.3 4.8 30.0 18.7 19.7 13.7 20.5 8.4 13.8 55.7 28.1 36.5 19.0 43.0 40.3 30.2 SHISA8 "C22orf17, Orf26" ENSG00000234965 "Shisa family member 8" B8ZZ34 22 41909554-41914667 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 13 "adrenal gland: 13.8;brain: 51.1" "Cell type enriched" "Detected in some" 18 "Horizontal cells: 477.8" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 9 "cerebellum: 51.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEK 293: 19.3" "Group enriched" "Detected in many" 4 "cerebellum: 7.8;olfactory bulb: 15.7;white matter: 4.0" "Low region specificity" "Detected in all" HPA059173 Uncertain NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "HPA059173: AB_2683938" "unprognostic (8.76e-2)" "unprognostic (2.98e-4)" "unprognostic (1.03e-1)" "prognostic favorable (2.76e-4)" "unprognostic (4.42e-2)" "unprognostic (1.45e-3)" "unprognostic (4.40e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-1)" "unprognostic (2.57e-1)" "unprognostic (1.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.12e-1)" "unprognostic (8.59e-2)" "unprognostic (2.60e-2)" "unprognostic (6.22e-4)" "unprognostic (7.84e-2)" 0.0 13.8 1.7 0.5 0.5 0.1 0.0 51.1 3.4 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 1.3 0.6 0.7 0.4 0.0 0.1 1.2 1.5 3.4 0.0 0.0 0.1 1.7 0.0 3.8 0.1 0.0 0.3 0.8 0.0 0.3 0.3 1.5 0.0 5.3 2.5 0.2 0.2 5.4 0.0 0.1 0.1 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.3 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 51.1 3.4 0.6 0.7 1.5 3.4 3.8 5.3 5.4 0.8 0.1 0.0 0.0 0.3 10.8 0.0 0.0 0.0 0.0 11.5 22.7 0.0 3.7 0.0 0.0 0.0 4.2 0.0 0.5 0.0 1.9 0.0 1.1 5.2 0.5 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.0 0.0 0.0 477.8 25.9 0.0 0.0 0.3 0.0 1.1 0.0 0.1 0.0 0.0 0.0 1.5 0.0 1.0 1.6 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 4.5 0.0 0.0 0.1 1.9 2.3 0.0 0.0 0.0 0.3 0.0 0.0 0.1 TNFRSF13C "BAFFR, CD268" ENSG00000159958 "TNF receptor superfamily member 13C" Q96RJ3 22 41922032-41926806 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 33.8;lymphoid tissue: 58.1" "Cell type enriched" "Detected in some" 10 "B-cells: 194.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 36 "memory B-cell: 22.5;naive B-cell: 29.1" "Lineage enriched" "Detected in single" 40 "B-cells: 29.1" "Group enriched" "Detected in some" 6 "REH: 21.0;U-698: 10.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA003246, CAB008380" Enhanced NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "CAB008380: AB_590602, HPA003246: AB_1078264" "unprognostic (3.43e-4)" "prognostic favorable (4.44e-7)" "unprognostic (6.52e-2)" "unprognostic (9.10e-2)" "unprognostic (7.64e-3)" "unprognostic (4.83e-3)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.95e-1)" "unprognostic (1.27e-1)" "unprognostic (2.51e-2)" "unprognostic (1.66e-1)" "unprognostic (4.79e-8)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (1.77e-1)" "unprognostic (9.44e-2)" 0.8 0.8 2.1 17.7 1.3 6.0 0.5 1.6 1.9 0.2 0.6 2.1 1.2 0.3 0.3 1.5 0.4 1.0 0.4 1.9 2.0 0.8 0.3 1.0 39.0 3.6 2.1 0.1 0.1 0.1 0.2 0.3 2.2 0.5 1.1 0.4 1.7 0.1 2.3 3.3 33.8 0.1 2.7 58.1 2.5 0.7 2.1 3.4 1.1 0.5 54.6 1.8 0.5 2.0 0.3 0.2 1.1 2.3 0.0 0.0 0.4 0.2 0.1 0.2 0.8 0.9 0.5 1.9 0.4 0.2 0.2 0.4 0.7 0.0 0.3 0.4 2.3 0.2 0.4 0.2 0.1 1.7 0.4 0.1 0.0 0.4 0.1 0.1 0.0 0.7 0.4 1.9 0.2 0.7 1.6 1.8 0.7 0.1 0.1 21.0 2.4 1.6 0.0 0.2 1.3 0.3 0.1 0.4 0.3 0.2 0.4 2.2 0.2 0.5 2.5 0.9 0.3 2.0 1.1 10.9 0.1 1.8 0.5 0.7 0.1 0.2 0.2 0.2 0.3 22.5 0.3 0.2 0.1 29.1 0.4 0.4 0.3 0.3 0.3 0.4 0.2 1.1 2.1 1.3 1.6 1.9 1.9 2.0 3.6 2.1 2.2 2.7 2.1 2.0 0.1 0.0 1.1 0.0 194.5 0.1 0.4 0.0 1.2 1.0 1.6 1.3 1.4 0.0 0.0 0.0 0.0 0.2 2.6 0.3 0.0 0.0 0.1 2.6 0.5 0.3 1.2 0.4 0.0 0.0 0.2 0.7 0.5 4.3 0.0 1.5 0.0 0.2 0.1 8.4 0.1 0.1 0.0 0.6 0.0 0.0 0.0 1.3 0.0 6.5 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 18.0 0.3 0.1 0.2 0.0 0.4 0.0 0.5 0.4 1.5 1.4 0.3 0.0 0.1 3.4 0.2 0.4 0.2 CENPM "C22orf18, CENP-M, MGC861, Pane1" ENSG00000100162 "Centromere protein M" Q9NSP4 22 41938737-41947152 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.0;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 116.7;Erythroid cells: 60.0;Plasma cells: 70.8;Respiratory ciliated cells: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "T-reg: 50.8" "Group enriched" "Detected in many" 6 "B-cells: 38.6;T-cells: 50.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042404 Enhanced NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "HPA042404: AB_2677981" "unprognostic (3.78e-2)" "prognostic favorable (3.40e-5)" "unprognostic (7.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.02e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (5.50e-5)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (1.63e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (5.99e-7)" "unprognostic (9.54e-3)" "unprognostic (2.44e-1)" "unprognostic (8.73e-2)" "unprognostic (5.61e-2)" 1.3 1.5 0.6 9.9 0.6 29.0 1.9 1.8 1.1 2.3 0.3 9.9 8.4 1.7 0.1 9.9 10.8 2.0 0.7 0.5 0.7 2.3 1.6 3.8 25.1 0.8 0.8 0.7 0.7 0.3 0.5 3.2 0.8 1.4 5.3 0.1 3.6 0.3 0.9 8.0 8.3 1.8 0.5 10.6 6.1 12.8 1.0 22.6 0.8 0.4 16.3 2.0 4.0 0.5 79.1 79.0 43.5 28.8 3.3 3.3 18.4 37.8 19.4 65.2 66.2 92.3 41.0 101.5 27.8 20.2 42.2 29.5 32.9 38.8 16.2 29.4 137.4 47.8 82.3 64.9 3.2 91.4 51.9 2.7 2.9 42.1 19.3 6.9 24.8 91.5 36.7 95.0 38.8 121.9 91.9 94.8 23.6 47.5 58.1 86.8 43.4 105.6 26.9 46.5 49.3 9.4 58.5 34.5 20.6 7.2 32.8 58.4 12.5 62.8 93.4 42.0 64.1 50.5 38.0 95.2 21.9 75.9 70.0 1.8 0.3 0.0 6.2 0.2 8.8 27.9 18.6 8.4 0.7 38.6 3.5 4.6 1.1 7.4 0.2 0.4 50.8 7.9 0.6 0.6 1.8 1.1 0.5 0.7 0.8 0.8 0.8 0.5 1.0 0.5 0.4 0.0 3.4 0.3 50.7 2.0 4.8 17.8 1.8 1.9 10.9 10.3 0.6 0.0 7.9 0.0 0.0 39.7 5.4 25.3 17.6 2.1 4.5 116.7 4.2 2.6 7.7 60.0 0.5 0.7 38.9 6.4 10.7 18.0 2.5 15.8 3.6 1.3 43.4 3.3 0.8 34.5 28.5 2.9 3.5 6.7 1.2 5.4 7.2 1.0 1.8 0.1 2.1 1.0 0.2 1.5 8.4 0.4 70.8 2.8 4.0 0.3 102.6 0.6 0.0 0.2 7.0 36.4 29.8 13.3 1.0 8.8 18.5 2.9 36.6 9.0 LINC00634 ENSG00000205704 "Long intergenic non-protein coding RNA 634" 22 41952174-41958933 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 9 "brain: 33.2;choroid plexus: 10.7" "Group enriched" "Detected in some" 35 "Astrocytes: 5.2;Excitatory neurons: 4.0;Inhibitory neurons: 3.6;Oligodendrocyte precursor cells: 3.5;Oligodendrocytes: 1.6" "Cancer enriched" "Detected in single" 13 "glioma: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 2.9;SCLC-21H: 2.7" HPA029815 Approved "Nuclear speckles,Cytosol" NA NA "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" Cytosol "HPA029815: AB_10601803" "unprognostic (1.42e-1)" "unprognostic (8.80e-4)" "unprognostic (3.93e-4)" "unprognostic (9.78e-2)" "unprognostic (2.94e-2)" "unprognostic (1.53e-1)" "unprognostic (1.72e-4)" "unprognostic (6.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.10e-2)" "unprognostic (1.17e-2)" "unprognostic (6.00e-2)" "unprognostic (1.11e-6)" "unprognostic (5.40e-2)" "unprognostic (5.76e-2)" "unprognostic (2.99e-1)" "unprognostic (3.17e-1)" 0.0 2.1 27.4 0.0 25.9 0.1 0.0 16.3 33.2 0.0 10.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 30.2 22.6 0.0 0.0 0.0 0.0 19.0 23.6 0.0 0.0 0.0 0.0 17.9 0.1 0.0 2.4 0.0 0.3 0.0 0.0 0.0 0.0 15.6 0.0 0.2 1.0 30.1 0.0 0.0 0.0 0.1 0.0 21.9 0.3 0.0 1.3 1.3 0.0 0.7 0.8 0.0 0.0 0.2 0.3 0.4 1.0 2.4 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.9 2.1 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.6 0.6 0.0 0.0 2.5 0.1 1.5 0.0 0.6 1.0 1.4 0.3 0.3 2.0 2.9 0.5 0.1 0.0 0.1 2.7 1.8 0.1 0.1 0.3 0.2 0.3 0.0 0.0 0.2 1.1 0.0 0.3 0.8 1.7 2.4 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 25.9 16.3 33.2 30.2 22.6 19.0 23.6 17.9 15.6 30.1 21.9 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 WBP2NL "FLJ26145, GRAMD7, MGC26816, PAWP" ENSG00000183066 "WBP2 N-terminal like" Q6ICG8 22 41998725-42058456 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 17.8" "Group enriched" "Detected in many" 10 "Early spermatids: 254.5;Late spermatids: 807.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048557 Enhanced Approved Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "HPA048557: AB_2680440" "unprognostic (1.90e-2)" "unprognostic (2.25e-4)" "unprognostic (2.77e-3)" "unprognostic (6.12e-2)" "unprognostic (6.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (1.04e-2)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (9.84e-4)" "unprognostic (3.31e-2)" "unprognostic (4.19e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" "unprognostic (2.85e-3)" "unprognostic (9.36e-5)" 0.2 0.1 0.6 0.0 0.6 0.0 0.7 0.6 0.9 0.2 0.0 0.2 0.1 0.2 1.2 0.1 0.5 0.2 0.0 0.6 0.6 0.3 0.1 0.3 0.2 1.0 0.7 0.6 0.7 0.4 0.3 0.1 1.0 0.3 0.1 0.7 0.5 0.3 0.1 0.4 0.2 0.1 0.8 0.2 0.3 17.8 0.5 0.1 0.6 0.1 0.1 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.6 0.6 0.9 0.6 0.6 1.0 0.7 1.0 0.8 0.5 1.4 0.3 0.0 2.8 50.6 4.3 0.4 2.1 1.0 2.8 16.4 1.8 2.4 0.7 2.8 3.7 0.0 20.9 2.2 0.6 1.7 3.9 0.9 254.5 0.9 1.5 1.3 4.8 0.4 16.0 1.3 1.0 0.9 1.5 1.3 0.0 4.7 2.2 1.5 1.4 10.1 18.6 2.2 4.1 2.8 1.9 807.7 6.5 2.3 1.8 9.4 1.8 2.9 3.1 9.5 16.6 0.9 3.9 5.7 1.5 1.2 3.4 2.0 0.8 23.0 0.0 0.6 0.7 30.6 20.2 1.2 0.9 1.9 1.9 1.6 2.7 1.4 NAGA D22S674 ENSG00000198951 Alpha-N-acetylgalactosaminidase P17050 22 42058334-42070842 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 65.0;Hofbauer cells: 91.6;Kupffer cells: 64.4;monocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 202.5;intermediate monocyte: 249.1;myeloid DC: 195.2;non-classical monocyte: 257.9;plasmacytoid DC: 119.8" "Group enriched" "Detected in all" 6 "dendritic cells: 195.2;monocytes: 257.9" "Cell line enhanced" "Detected in all" "HMC-1: 190.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000649 Enhanced "Intracellular and membrane" NA NA 2200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "HPA000649: AB_1079448" "unprognostic (3.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-2)" "unprognostic (4.27e-1)" "unprognostic (1.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.53e-2)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (3.68e-2)" "unprognostic (1.92e-3)" "unprognostic (8.95e-2)" "unprognostic (2.53e-1)" 21.4 12.7 9.3 32.3 10.4 20.1 13.4 10.3 10.1 20.6 17.0 26.1 20.4 17.2 12.4 17.2 20.0 22.1 16.0 8.9 11.5 14.9 31.9 27.1 20.8 13.9 10.8 17.0 11.4 39.2 11.7 42.8 12.6 18.2 26.7 7.7 17.3 18.6 7.7 13.4 24.2 28.3 12.2 20.3 16.6 9.0 12.0 13.9 15.1 12.3 19.0 24.8 13.7 14.4 27.8 14.0 21.7 38.9 37.0 41.9 15.9 22.4 45.7 37.9 39.2 31.4 39.9 13.5 13.5 49.1 22.9 19.2 16.7 27.4 22.3 31.0 21.2 33.5 20.1 21.5 21.5 28.1 190.4 28.9 23.8 34.0 14.4 19.5 63.4 11.6 12.4 56.0 30.2 32.3 10.4 11.5 5.8 25.3 18.5 23.0 11.0 24.2 29.4 32.7 6.7 7.7 29.8 27.0 29.3 19.1 40.4 50.9 34.4 26.6 31.8 17.1 20.7 30.9 33.3 10.9 28.3 52.7 33.4 36.5 202.5 25.1 13.6 249.1 13.8 10.5 14.1 12.7 195.2 6.9 9.2 8.4 9.9 18.8 257.9 119.8 18.3 121.0 9.3 10.4 10.3 10.1 8.9 11.5 13.9 10.8 12.6 12.2 12.0 14.4 6.5 9.6 6.7 4.6 8.2 3.3 9.4 10.9 5.7 2.8 6.7 6.2 4.2 4.3 11.3 7.3 8.4 46.1 11.0 27.3 3.9 15.4 15.8 5.6 8.8 11.2 6.0 12.4 1.1 8.1 65.0 13.8 6.1 10.2 9.5 3.2 9.3 33.6 91.6 0.0 2.0 15.0 6.1 64.4 36.3 17.9 7.2 52.5 19.6 12.2 65.8 5.9 6.2 0.5 2.0 13.0 23.9 6.8 22.2 6.0 40.0 9.8 15.7 6.4 19.7 6.1 10.0 10.7 5.2 7.1 3.4 58.3 6.9 6.5 15.4 10.0 PHETA2 "DKFZp686J07229, FAM109B, IPIP27B, SES2" ENSG00000177096 "PH domain containing endocytic trafficking adaptor 2" Q6ICB4 22 42074248-42079438 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 14.1;Endometrial stromal cells: 10.3;Extravillous trophoblasts: 27.4;Syncytiotrophoblasts: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 20.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 36.8;fHDF/TERT166: 33.7;HSkMC: 32.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA000647 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA000647: AB_1078800" "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (5.90e-2)" "unprognostic (6.66e-3)" "unprognostic (1.56e-2)" "unprognostic (9.61e-3)" "unprognostic (2.40e-1)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (8.80e-2)" "unprognostic (7.52e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (2.81e-2)" "unprognostic (4.03e-2)" 11.1 4.3 2.8 6.6 2.7 4.6 9.7 2.5 2.8 12.2 4.3 11.4 6.0 15.4 2.8 9.6 9.8 8.2 8.5 2.5 2.8 7.1 1.9 9.7 4.1 3.1 2.7 5.2 18.2 4.8 5.8 15.6 2.8 9.9 8.5 0.4 12.7 7.6 2.5 8.3 9.4 12.9 3.1 7.8 13.4 2.5 2.8 2.4 5.8 3.1 4.2 11.3 9.1 2.8 0.1 0.0 0.0 0.2 30.9 36.8 0.2 21.4 17.5 13.0 12.9 22.6 20.5 0.1 13.1 33.7 0.0 3.7 0.1 0.2 6.9 0.0 0.0 0.0 29.1 0.2 17.6 0.0 17.1 32.3 9.5 20.1 2.5 0.0 29.3 0.3 0.2 0.0 14.1 0.4 0.1 0.2 2.4 1.1 0.0 0.2 0.1 0.3 5.9 0.0 0.2 0.2 9.2 0.1 0.1 0.2 14.1 0.0 30.0 0.2 13.8 31.5 0.1 0.5 0.5 0.3 0.0 0.4 24.0 20.0 4.3 1.7 1.3 4.9 0.2 0.5 0.8 1.0 8.4 0.2 0.6 1.2 0.3 0.7 2.8 3.9 0.6 3.2 2.8 2.7 2.5 2.8 2.5 2.8 3.1 2.7 2.8 3.1 2.8 2.8 4.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.8 2.4 0.0 0.0 0.0 0.0 0.0 14.1 0.2 0.0 3.9 5.7 0.0 1.1 10.3 3.0 0.0 0.0 0.0 7.0 27.4 6.6 0.0 2.8 0.0 3.8 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 22.2 0.2 3.6 0.0 0.0 SMDT1 "C22orf32, DDDD, dJ186O1.1, EMRE" ENSG00000183172 "Single-pass membrane protein with aspartate rich tail 1" Q9H4I9 22 42079691-42084284 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032117, HPA060340" Uncertain Supported Nucleoplasm,Mitochondria NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Nucleoplasm "HPA032117: AB_10601093, HPA060340: AB_2684257" "unprognostic (1.11e-2)" "unprognostic (1.46e-3)" "unprognostic (5.77e-2)" "prognostic favorable (5.32e-8)" "unprognostic (1.25e-1)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (4.84e-2)" "prognostic favorable (5.87e-4)" "unprognostic (2.96e-1)" "prognostic favorable (2.36e-9)" "unprognostic (1.91e-1)" "unprognostic (2.65e-1)" "unprognostic (1.45e-1)" "unprognostic (9.72e-3)" 12.2 13.9 21.6 6.1 22.2 17.6 19.5 25.7 27.7 14.6 21.2 14.7 10.3 12.3 19.5 12.6 15.2 7.4 20.0 22.1 22.0 18.2 15.1 9.7 16.1 21.6 21.4 22.5 21.5 18.0 14.9 7.3 22.2 16.1 11.2 16.0 22.7 13.4 35.6 14.8 13.5 8.4 21.3 12.6 17.7 6.9 21.3 12.4 18.6 37.9 12.2 12.4 11.9 22.4 5.7 3.7 7.4 8.9 13.1 9.5 5.8 2.0 10.0 12.1 10.5 7.1 5.3 7.8 2.4 10.3 3.4 6.1 9.8 10.4 7.7 3.8 15.7 4.7 8.1 10.3 16.5 8.6 5.9 7.4 17.3 4.8 9.9 6.9 12.2 5.1 7.9 12.3 8.4 11.2 12.1 13.0 2.8 14.1 2.7 10.8 6.5 20.8 15.5 6.4 9.2 6.0 5.0 11.1 12.8 3.7 9.3 9.3 4.8 5.1 5.3 4.5 3.9 8.2 9.8 16.9 7.9 8.5 4.1 4.0 5.8 2.9 3.1 3.1 5.9 5.9 8.6 4.5 8.4 7.2 9.3 6.0 0.5 5.5 4.5 6.4 5.4 5.4 21.6 22.2 25.7 27.7 22.1 22.0 21.6 21.4 22.2 21.3 21.3 22.4 161.1 83.3 109.3 11.8 295.0 166.7 202.2 157.3 191.2 71.6 400.9 477.3 350.9 237.4 160.3 204.1 20.9 308.7 127.8 285.6 573.2 160.0 114.0 156.8 81.1 138.2 345.2 135.7 10.5 199.6 190.6 127.8 150.3 127.2 91.4 55.4 161.3 380.1 256.1 55.5 12.8 356.5 262.4 164.5 200.6 131.9 189.2 187.7 211.7 5.6 125.8 196.4 124.6 7.5 13.8 193.7 314.0 149.0 275.8 238.2 486.7 623.4 223.7 109.5 124.9 133.6 202.7 256.0 55.5 271.5 274.1 308.8 186.3 151.7 308.8 272.2 NDUFA6 "B14, CI-B14, LYRM6, NADHB14" ENSG00000184983 "NADH:ubiquinone oxidoreductase subunit A6" P56556 22 42085526-42090884 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1536.8;Distal tubular cells: 954.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 181.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (3.48e-2)" "prognostic favorable (3.87e-4)" "unprognostic (7.00e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.65e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (4.02e-2)" "unprognostic (2.71e-2)" "unprognostic (1.47e-2)" "unprognostic (8.28e-2)" "unprognostic (3.61e-1)" "prognostic favorable (1.05e-6)" "unprognostic (2.15e-1)" "unprognostic (1.63e-1)" "unprognostic (9.49e-2)" "unprognostic (4.84e-2)" 9.8 30.9 14.3 19.2 13.1 25.9 28.0 13.9 18.9 9.6 19.1 37.6 12.5 15.7 21.3 38.5 8.8 10.9 124.2 13.4 15.0 37.3 51.4 15.4 20.6 14.9 13.7 9.3 31.2 109.2 17.8 25.2 16.1 17.8 57.6 19.8 28.2 18.8 115.1 12.4 38.1 14.2 12.9 18.0 30.7 22.2 15.0 3.7 20.3 101.5 11.9 24.0 9.3 13.1 48.1 1.9 4.5 44.2 94.6 78.9 6.3 0.3 0.3 0.8 1.0 54.1 99.2 0.7 1.4 67.4 2.3 47.9 1.2 1.2 4.5 0.4 0.7 1.0 10.2 181.7 0.9 55.3 73.1 28.1 27.7 57.0 102.2 1.6 33.9 2.0 73.9 94.1 1.6 90.8 35.6 3.7 34.5 134.6 138.7 60.2 48.6 0.3 1.3 6.0 1.0 31.8 96.4 56.5 143.4 6.0 113.2 0.6 0.0 2.3 110.2 41.9 72.6 41.5 64.0 4.5 35.8 95.8 98.9 127.4 109.8 123.4 78.2 114.0 84.8 111.8 106.0 72.9 156.5 85.3 88.4 88.2 37.7 98.6 99.4 99.3 109.0 213.5 14.3 13.1 13.9 18.9 13.4 15.0 14.9 13.7 16.1 12.9 15.0 13.1 103.3 60.9 94.1 15.7 103.8 185.7 228.5 445.8 76.8 58.7 105.7 132.8 1536.8 164.5 189.2 180.3 45.9 422.1 105.6 349.0 954.8 267.3 181.3 104.0 99.6 123.3 170.8 140.8 9.7 253.9 443.7 152.2 114.7 106.6 105.2 70.1 94.2 598.6 357.9 35.3 13.4 293.3 386.6 114.6 255.4 52.0 100.9 145.8 288.1 5.6 198.0 129.4 117.4 5.0 9.3 260.5 361.8 110.6 166.7 202.6 517.5 597.8 131.4 99.7 105.2 98.9 329.1 142.5 163.8 159.9 186.0 764.1 123.8 117.7 301.9 230.4 CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 320.0" "Group enriched" "Detected in many" 35 "Hepatocytes: 512.8;Proximal enterocytes: 465.2" "Cancer enriched" "Detected in many" 35 "liver cancer: 90.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Hep G2: 1.8" "Low region specificity" "Detected in many" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "HPA045223: AB_10962927" "unprognostic (4.40e-3)" "unprognostic (7.68e-3)" "unprognostic (5.45e-2)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (1.29e-4)" "unprognostic (3.83e-2)" "unprognostic (7.27e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-1)" "unprognostic (4.03e-4)" "unprognostic (2.11e-2)" "unprognostic (5.61e-5)" "unprognostic (3.01e-1)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (4.82e-5)" 0.1 0.2 0.2 0.0 0.3 0.3 0.1 0.8 0.2 0.1 0.3 0.3 3.7 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.3 320.0 0.1 0.1 0.2 0.0 0.2 0.8 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.2 11.7 0.0 0.1 0.3 0.1 0.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.8 0.2 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.3 0.6 0.0 1.1 5.5 0.7 0.5 0.7 1.3 2.8 7.3 1.1 1.4 0.4 2.8 0.7 1.8 2.1 0.1 0.6 2.9 1.9 0.7 3.1 0.8 0.6 0.6 1.2 0.0 6.5 0.6 0.1 0.3 4.1 1.4 0.0 0.7 5.7 512.8 0.1 11.8 9.4 7.6 0.0 5.6 0.0 13.6 0.0 0.4 0.0 0.0 0.1 0.7 0.0 5.0 4.9 0.7 11.3 1.5 0.4 0.6 465.2 0.5 1.3 2.3 0.0 0.4 2.1 0.8 0.4 0.6 1.1 0.4 1.0 0.1 3.4 0.3 TCF20 "AR1, SPBP" ENSG00000100207 "Transcription factor 20" Q9UGU0 22 42160013-42343616 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 127.0;Inhibitory neurons: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017849, HPA036786" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Nuclear bodies" "CAB017849: , HPA036786: AB_2675313" "unprognostic (2.17e-1)" "unprognostic (2.12e-2)" "prognostic favorable (1.88e-4)" "unprognostic (2.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (4.89e-4)" "unprognostic (1.77e-1)" "unprognostic (2.36e-1)" "unprognostic (1.40e-2)" "unprognostic (2.16e-3)" "unprognostic (7.30e-2)" "unprognostic (1.17e-3)" "unprognostic (3.07e-3)" "unprognostic (4.94e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" 7.1 6.5 4.2 1.7 3.1 1.6 7.5 0.0 2.9 10.2 0.0 9.1 1.6 9.0 0.2 16.3 6.9 1.0 4.9 3.7 2.4 7.6 7.4 7.1 1.6 0.9 1.0 7.6 8.2 1.2 7.4 1.2 1.1 6.9 1.3 0.9 9.9 1.0 5.7 14.3 10.0 1.4 0.0 7.3 8.0 15.3 1.8 2.3 9.6 1.3 1.6 7.8 11.0 2.1 6.6 2.3 3.2 2.1 1.0 2.1 5.5 4.2 2.8 2.1 3.5 5.0 2.5 10.9 3.6 1.1 3.1 5.4 3.9 3.3 1.2 8.5 3.9 3.4 2.2 1.6 1.5 6.0 4.7 1.2 2.9 3.0 3.0 0.9 1.0 3.1 4.1 3.9 1.6 3.0 9.4 1.8 3.4 2.2 3.1 4.7 2.0 5.7 0.5 5.2 6.2 2.0 2.7 2.0 2.7 2.0 1.2 4.8 3.9 3.8 8.9 3.9 1.9 7.0 6.2 4.5 2.3 4.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.1 0.0 2.9 3.7 2.4 0.9 1.0 1.1 0.0 1.8 2.1 10.0 0.0 9.6 23.5 9.1 22.6 11.3 19.4 12.0 25.1 11.5 6.9 7.3 17.2 10.1 9.2 18.8 6.3 11.0 16.6 0.0 10.8 127.0 14.2 9.9 9.3 16.8 9.9 54.0 7.5 5.5 8.1 10.7 22.2 1.3 10.0 8.9 12.6 6.2 10.1 63.5 13.8 12.2 12.4 13.3 36.2 12.5 9.4 7.2 22.5 12.0 5.6 6.2 29.7 55.0 13.3 13.5 6.4 8.7 20.9 13.0 6.0 13.4 12.6 6.6 5.8 8.5 19.1 13.4 19.5 22.9 4.5 13.0 4.3 17.9 14.6 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 RRP7A "CGI-96, Rrp7" ENSG00000189306 "Ribosomal RNA processing 7 homolog A" Q9Y3A4 22 42508344-42519796 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001586, HPA046768" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA001586: AB_1078506, HPA046768: AB_2679796" "unprognostic (8.46e-2)" "unprognostic (3.30e-3)" "unprognostic (5.96e-2)" "unprognostic (3.21e-3)" "unprognostic (9.71e-3)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.21e-5)" "unprognostic (6.73e-2)" "unprognostic (3.00e-1)" "unprognostic (2.28e-1)" "unprognostic (2.41e-1)" "unprognostic (3.22e-2)" "unprognostic (9.53e-3)" "unprognostic (8.02e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" 14.0 16.5 15.8 9.8 18.0 12.3 15.4 14.3 17.0 13.9 11.6 13.9 6.2 13.7 28.2 18.7 13.9 4.7 15.6 16.4 14.1 22.3 18.4 13.0 14.2 15.0 15.3 17.3 14.5 11.1 11.2 6.6 15.5 22.3 6.1 5.2 15.6 7.5 13.8 15.7 13.8 6.4 13.1 18.4 15.0 12.8 14.6 10.3 13.6 5.2 10.2 14.8 14.0 15.7 23.9 34.6 21.1 24.7 13.7 8.8 35.9 21.0 13.7 27.0 22.8 47.4 14.3 41.4 10.6 15.5 13.4 29.3 25.4 28.1 11.1 11.2 50.3 21.8 26.4 23.6 11.2 57.1 19.4 12.1 16.4 35.6 17.7 10.5 15.6 21.6 30.7 12.1 15.9 51.5 54.8 23.0 17.9 20.5 25.5 88.9 19.9 17.6 13.7 31.5 9.8 8.4 14.8 50.5 20.7 8.9 18.2 23.9 12.4 22.9 25.1 16.4 21.1 18.5 16.0 48.8 18.2 20.3 31.2 16.1 28.0 22.4 21.2 33.2 20.4 26.1 18.4 19.7 21.8 32.5 20.0 18.8 5.7 20.4 37.2 37.6 17.1 26.2 15.8 18.0 14.3 17.0 16.4 14.1 15.0 15.3 15.5 13.1 14.6 15.7 32.2 22.4 36.6 5.9 48.6 43.8 95.1 41.4 12.5 26.6 28.6 28.3 16.0 31.5 37.2 22.0 16.7 93.0 50.3 48.4 17.6 71.3 55.8 24.2 25.4 38.6 26.4 64.6 7.5 27.2 133.8 31.0 34.7 28.8 47.5 46.3 37.5 32.6 94.8 26.9 6.8 39.8 28.5 43.3 47.4 118.3 22.1 39.5 33.8 6.5 116.5 24.8 68.0 1.0 7.9 52.1 46.0 18.4 51.4 94.3 38.5 42.1 34.4 28.5 6.6 30.2 37.0 33.5 24.7 27.3 37.8 120.4 40.2 45.2 59.4 106.3 SERHL2 ENSG00000183569 "Serine hydrolase like 2" Q9H4I8 22 42553617-42574382 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "breast: 420.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 18.1;Hepatic stellate cells: 21.8;Sertoli cells: 19.7" "Group enriched" "Detected in all" 5 "breast cancer: 8.0;prostate cancer: 5.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "memory B-cell: 3.5;naive B-cell: 8.4;plasmacytoid DC: 3.9" "Group enriched" "Detected in many" 12 "B-cells: 8.4;dendritic cells: 3.9" "Cell line enriched" "Detected in many" 10 "SK-BR-3: 276.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "unprognostic (3.14e-1)" "unprognostic (1.56e-2)" "unprognostic (8.61e-2)" "unprognostic (2.52e-2)" "unprognostic (3.27e-1)" "unprognostic (7.24e-2)" "unprognostic (1.25e-3)" "unprognostic (1.47e-2)" "unprognostic (1.55e-3)" "unprognostic (1.23e-1)" "unprognostic (1.55e-2)" "unprognostic (2.92e-1)" "unprognostic (7.04e-2)" "unprognostic (4.08e-2)" "unprognostic (2.06e-1)" "unprognostic (1.52e-1)" "unprognostic (1.42e-1)" 2.0 2.6 4.8 1.0 5.9 2.1 420.6 5.8 7.4 3.4 3.8 2.3 0.7 3.1 36.4 2.3 3.4 1.6 3.9 4.8 5.2 3.0 1.7 1.6 4.0 4.3 4.3 13.7 0.6 5.3 1.1 0.8 4.7 10.2 1.2 1.1 6.3 5.4 1.4 13.9 2.1 2.0 4.2 1.9 3.0 2.9 5.1 0.7 2.8 1.3 1.4 2.5 2.8 5.1 0.7 0.0 1.6 3.0 3.7 8.7 0.5 2.2 2.0 2.0 2.6 0.1 0.5 1.3 1.2 5.4 1.2 1.4 1.5 0.9 1.1 0.5 0.9 1.2 0.1 2.9 1.9 1.8 2.5 8.7 1.5 1.3 0.2 1.7 0.6 0.2 11.7 0.2 2.1 5.8 29.0 1.8 0.3 0.7 0.7 15.6 0.0 0.5 0.9 0.7 0.5 0.8 0.5 276.7 0.3 2.9 1.2 1.9 2.0 1.0 0.3 1.5 0.0 1.2 0.1 13.5 1.8 0.2 1.2 0.0 0.0 0.4 0.1 0.0 0.2 3.5 0.1 0.3 0.1 8.4 0.0 0.1 0.0 0.2 0.1 3.9 0.0 0.3 4.8 5.9 5.8 7.4 4.8 5.2 4.3 4.3 4.7 4.2 5.1 5.1 2.6 3.2 0.0 3.6 3.2 1.3 6.1 1.5 1.8 1.4 18.1 6.3 0.5 1.5 2.4 12.9 0.0 5.4 3.2 0.5 3.9 1.3 3.5 2.4 2.2 8.5 0.0 2.7 5.0 0.2 3.7 4.0 0.5 5.0 0.0 0.7 21.8 1.2 1.2 1.7 4.4 1.7 0.0 1.6 1.9 3.1 5.3 2.4 5.4 4.7 0.0 4.1 1.0 3.0 9.9 0.5 0.6 6.8 0.1 13.2 0.4 1.0 2.5 1.5 19.7 3.1 3.3 5.3 8.3 2.6 1.6 8.1 1.3 3.3 1.2 4.5 POLDIP3 "KIAA1649, PDIP3, PDIP46, SKAR" ENSG00000100227 "DNA polymerase delta interacting protein 3" Q9BY77 22 42583721-42614962 "Predicted intracellular proteins" "mRNA transport, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 129.3;Late spermatids: 469.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018419, HPA048790" Approved Enhanced "Nuclear speckles,Cytoplasmic bodies" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nuclear speckles" "Cytoplasmic bodies" "HPA018419: AB_1856928, HPA048790: AB_2680522" "unprognostic (2.00e-1)" "unprognostic (1.55e-1)" "unprognostic (1.32e-1)" "unprognostic (7.05e-3)" "prognostic favorable (7.79e-4)" "unprognostic (2.82e-1)" "unprognostic (1.17e-2)" "unprognostic (5.44e-2)" "unprognostic (8.16e-2)" "unprognostic (4.49e-3)" "unprognostic (2.48e-1)" "unprognostic (5.96e-2)" "prognostic favorable (3.36e-4)" "unprognostic (3.73e-2)" "unprognostic (3.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.19e-1)" 25.9 36.5 51.7 26.3 56.0 68.2 33.3 52.5 54.9 43.2 45.5 36.7 25.8 40.5 34.7 42.6 53.2 24.0 34.4 50.2 51.1 40.6 33.2 36.3 36.2 59.2 54.1 91.1 35.9 34.4 35.6 32.6 53.3 41.3 29.3 30.1 37.7 33.4 34.9 39.1 31.8 35.4 50.6 38.6 44.4 30.8 54.1 48.6 37.6 34.5 46.4 34.8 34.3 58.1 43.7 43.7 96.3 45.4 42.7 48.7 61.7 49.0 41.1 73.6 54.6 51.6 29.5 73.3 30.8 58.2 34.9 49.5 101.0 55.8 57.1 35.6 74.9 58.4 50.8 53.6 39.5 91.9 57.5 33.8 62.5 54.1 56.0 61.4 52.5 54.1 63.7 47.0 58.8 48.5 76.3 65.3 53.5 56.4 40.5 96.5 87.7 49.5 61.4 27.9 31.5 27.2 59.6 51.1 53.0 56.2 47.4 67.4 48.3 46.7 56.0 31.8 50.1 45.3 59.5 67.1 37.8 56.0 67.4 23.3 36.9 29.8 30.9 34.8 32.0 26.9 27.3 26.3 41.9 26.2 29.7 27.1 21.2 28.6 30.9 21.5 31.0 38.7 51.7 56.0 52.5 54.9 50.2 51.1 59.2 54.1 53.3 50.6 54.1 58.1 15.8 19.2 15.1 10.4 28.6 19.6 23.7 13.1 22.2 30.1 23.0 20.6 13.3 17.2 16.0 20.2 20.9 36.5 23.1 22.9 21.5 29.1 129.3 22.9 20.7 18.9 19.2 25.6 7.1 24.9 39.7 23.2 21.4 23.4 24.1 18.8 16.1 19.0 22.2 25.2 8.8 15.8 16.2 25.7 17.9 469.0 21.8 19.9 19.6 18.7 40.3 23.6 22.6 11.6 17.4 26.4 21.2 24.8 24.5 37.2 19.2 20.3 19.5 17.1 46.0 19.3 18.5 33.0 34.5 22.9 17.6 52.1 23.0 22.6 19.0 28.6 CYB5R3 DIA1 ENSG00000100243 "Cytochrome b5 reductase 3" P00387 22 42617840-42649392 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 830.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001566 Approved Supported "Endoplasmic reticulum" NA NA 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "HPA001566: AB_1078601" "unprognostic (4.73e-2)" "unprognostic (2.93e-1)" "unprognostic (1.79e-1)" "unprognostic (1.89e-1)" "unprognostic (3.05e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.45e-1)" "unprognostic (8.22e-3)" "unprognostic (3.01e-1)" "unprognostic (2.72e-2)" "unprognostic (6.76e-2)" "unprognostic (3.33e-3)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-1)" "unprognostic (5.24e-2)" 404.4 310.5 147.1 87.4 152.9 82.7 272.2 145.7 189.9 237.3 115.0 192.4 94.8 248.4 58.8 152.4 174.0 139.5 374.3 138.7 163.9 182.9 279.4 201.3 76.3 194.7 174.2 218.3 89.1 62.0 137.4 107.8 169.9 181.4 74.9 27.3 149.8 239.3 203.0 233.6 138.1 200.2 154.8 101.4 182.0 142.7 156.7 54.0 157.8 140.5 72.3 216.7 210.0 160.2 125.5 78.6 126.6 78.6 830.9 654.7 74.4 359.2 330.0 262.2 232.4 104.0 95.6 58.8 156.6 668.8 113.8 112.4 85.3 178.0 133.7 63.9 187.3 83.6 127.3 202.4 211.0 118.4 149.5 397.4 138.1 188.9 124.5 190.8 220.0 74.0 73.5 296.3 361.9 137.9 116.8 108.4 51.0 129.2 142.7 84.9 153.8 131.3 202.0 90.6 56.1 73.2 118.6 113.2 134.0 92.6 90.6 112.0 340.9 282.0 175.3 192.3 137.9 78.3 91.2 72.4 328.8 67.8 237.9 126.3 104.0 300.3 75.9 135.3 76.6 110.1 72.8 83.9 154.0 102.7 50.8 54.0 53.8 63.5 176.7 140.8 95.0 86.4 147.1 152.9 145.7 189.9 138.7 163.9 194.7 174.2 169.9 154.8 156.7 160.2 238.5 86.6 62.2 17.0 51.7 110.1 95.5 184.8 27.3 16.7 52.3 73.2 106.4 105.8 100.9 60.7 4.2 110.0 37.0 90.5 49.0 216.4 4.8 51.4 82.9 161.5 83.7 113.9 12.3 107.0 199.3 183.4 38.2 65.4 62.8 57.8 180.2 230.4 108.3 16.8 16.1 45.8 142.4 50.6 112.0 17.0 253.9 67.7 176.1 25.3 112.5 91.0 33.0 7.1 26.4 156.8 85.6 280.6 36.7 82.3 116.9 110.8 53.3 18.4 190.7 62.5 202.5 23.8 45.5 57.5 112.7 117.9 43.0 233.1 55.2 96.4 ATP5MGL "ATP5K2, ATP5L2, dJ222E13.5" ENSG00000249222 "ATP synthase membrane subunit g like" Q7Z4Y8 22 42639803-42640601 "Predicted intracellular proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.4;brain: 2.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 11.6;Distal tubular cells: 5.9;Extravillous trophoblasts: 7.7;Hofbauer cells: 11.2;Syncytiotrophoblasts: 9.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044629 Uncertain Uncertain Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "HPA044629: AB_2679028" "unprognostic (4.53e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-2)" "unprognostic (5.67e-2)" "unprognostic (3.01e-2)" "unprognostic (3.36e-2)" "unprognostic (1.31e-2)" "unprognostic (1.70e-2)" "unprognostic (6.74e-2)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (4.17e-1)" "unprognostic (5.12e-2)" "unprognostic (1.85e-3)" 0.1 0.0 0.7 0.0 0.5 1.4 0.0 2.7 1.1 0.0 0.8 0.0 0.1 0.1 0.6 0.1 0.0 0.1 0.1 0.6 1.0 0.1 0.0 0.1 0.3 1.3 0.6 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.4 0.3 0.0 0.1 0.9 0.1 0.0 0.3 0.1 0.2 0.1 1.3 0.0 0.2 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.2 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.1 0.9 0.1 0.2 0.2 0.1 0.3 0.7 0.5 2.7 1.1 0.6 1.0 1.3 0.6 0.7 0.3 1.3 1.6 1.1 0.0 2.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.0 0.0 0.0 1.8 0.0 11.6 0.7 0.0 5.9 0.6 0.0 0.8 0.8 0.9 0.0 0.0 0.0 1.1 7.7 1.0 0.0 1.3 2.5 1.2 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.6 0.8 1.2 0.0 0.0 A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 70.7;Proximal tubular cells: 91.0;Urothelial cells: 74.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 38.7;ASC TERT1: 31.3;RPTEC TERT1: 27.1;TIME: 29.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001141 Uncertain Mitochondria NA NA 22000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria "HPA001141: AB_1078139" "unprognostic (2.59e-2)" "prognostic favorable (2.48e-4)" "unprognostic (2.24e-2)" "unprognostic (4.54e-3)" "unprognostic (7.41e-2)" "unprognostic (1.53e-1)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.30e-1)" "unprognostic (1.28e-1)" "unprognostic (4.82e-3)" "unprognostic (4.16e-2)" "unprognostic (1.80e-2)" "unprognostic (1.96e-1)" "unprognostic (8.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.74e-1)" 41.5 14.3 6.2 6.1 6.0 4.1 31.3 5.0 8.0 29.6 8.0 30.9 4.5 28.1 3.3 30.6 29.2 4.4 77.0 6.2 5.3 51.3 4.3 26.0 6.8 7.8 5.8 7.8 6.2 1.2 16.7 9.1 5.6 35.1 1.7 0.3 36.1 21.3 19.4 20.8 18.2 6.9 6.0 16.2 26.6 6.2 7.1 1.6 25.1 6.3 5.1 38.1 38.2 6.0 1.2 13.6 0.0 0.0 38.7 31.3 20.1 5.5 5.8 1.2 2.1 4.3 2.2 13.6 9.4 9.7 6.7 1.3 12.9 6.5 0.2 0.0 2.7 0.3 21.1 0.5 11.5 0.0 0.9 18.6 1.8 5.5 0.9 1.8 4.7 0.0 0.1 0.0 5.1 19.0 0.0 0.0 1.6 0.9 3.3 0.0 3.0 1.4 27.1 23.4 0.2 0.0 16.9 0.3 0.0 2.4 10.6 1.6 29.3 0.0 2.6 24.3 7.3 2.8 13.1 0.1 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 6.2 6.0 5.0 8.0 6.2 5.3 7.8 5.8 5.6 6.0 7.1 6.0 47.1 0.0 0.5 0.3 1.6 9.2 28.9 70.7 0.0 0.1 4.2 1.5 15.8 1.5 41.2 18.4 0.0 48.7 0.4 0.2 13.7 23.1 0.7 11.1 10.3 43.7 0.0 10.7 0.1 1.1 35.3 43.8 2.6 17.4 1.3 0.2 30.7 0.2 5.3 0.0 0.1 0.0 14.2 1.0 11.8 4.4 46.3 4.0 7.2 7.5 30.0 0.8 0.0 0.5 0.0 3.6 0.0 30.1 0.1 40.1 0.0 91.0 12.1 0.6 39.5 7.6 29.3 0.6 0.6 1.2 8.8 9.4 1.5 19.9 0.1 74.7 ARFGAP3 ARFGAP1 ENSG00000242247 "ADP ribosylation factor GTPase activating protein 3" Q9NP61 22 42796502-42858106 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000638 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "Golgi apparatus" "HPA000638: AB_1078188" "unprognostic (3.29e-2)" "unprognostic (6.08e-2)" "unprognostic (3.22e-1)" "prognostic favorable (8.97e-6)" "unprognostic (5.83e-2)" "unprognostic (8.85e-3)" "unprognostic (5.00e-3)" "unprognostic (1.00e-1)" "unprognostic (2.05e-1)" "unprognostic (1.31e-1)" "unprognostic (9.06e-3)" "unprognostic (1.67e-1)" "unprognostic (1.87e-1)" "unprognostic (2.52e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.65e-4)" "unprognostic (1.73e-1)" 30.1 88.9 16.5 34.1 17.4 47.8 30.9 19.5 20.4 56.1 23.2 26.9 36.5 32.2 53.3 22.1 22.9 36.6 23.6 17.9 20.6 53.2 49.2 32.3 28.1 20.5 18.7 20.7 85.8 38.0 38.1 34.8 20.3 64.7 30.6 35.5 68.5 40.2 31.3 20.7 51.1 30.8 19.0 26.0 43.2 49.5 19.6 25.9 61.3 21.8 32.6 45.2 23.4 21.0 59.6 19.3 41.1 24.7 57.2 94.1 17.3 111.8 76.4 50.5 60.9 23.5 32.8 30.1 24.5 102.9 41.8 14.4 18.7 33.0 54.7 18.5 25.4 35.7 27.6 37.4 79.6 31.9 53.2 42.0 57.6 42.6 75.9 71.9 52.4 27.4 16.1 132.0 89.6 15.7 49.4 17.5 6.7 32.7 23.2 31.1 92.3 38.3 80.7 27.5 14.6 9.0 54.3 21.5 46.0 30.6 22.7 24.4 67.0 58.7 42.5 52.1 30.7 94.7 48.2 33.1 41.9 34.0 46.7 86.2 33.2 36.8 45.1 44.4 58.8 27.1 29.7 39.8 32.5 26.1 19.2 27.2 50.8 49.4 50.9 53.1 28.8 30.1 16.5 17.4 19.5 20.4 17.9 20.6 20.5 18.7 20.3 19.0 19.6 21.0 40.8 38.5 54.8 27.4 41.7 26.6 86.9 43.0 19.9 42.8 43.1 29.5 26.5 37.1 62.1 57.0 18.8 18.8 67.3 36.4 66.5 65.9 19.1 60.5 89.9 42.4 49.1 17.5 26.1 64.3 23.7 58.1 30.1 96.3 65.9 28.4 30.4 37.3 28.7 33.7 28.8 53.0 46.8 21.7 89.3 15.0 48.1 68.2 69.4 35.6 33.7 40.5 38.1 43.7 40.0 83.0 15.6 45.5 110.0 121.5 70.9 62.9 65.5 33.7 39.5 80.0 65.5 178.7 67.6 14.6 26.7 59.9 49.6 39.0 22.7 86.7 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 TTLL1 C22orf7 ENSG00000100271 "Tubulin tyrosine ligase like 1" O95922 22 43039516-43089419 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.9;Spermatogonia: 32.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048392 Approved Approved Nucleoli,Mitochondria No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoli Mitochondria "HPA048392: AB_2680384" "unprognostic (1.02e-1)" "unprognostic (4.06e-3)" "unprognostic (1.51e-1)" "prognostic favorable (1.85e-4)" "unprognostic (6.18e-3)" "unprognostic (4.27e-3)" "prognostic unfavorable (2.34e-5)" "unprognostic (8.22e-2)" "unprognostic (2.16e-2)" "unprognostic (3.29e-1)" "unprognostic (4.47e-3)" "unprognostic (1.82e-1)" "prognostic favorable (1.68e-4)" "unprognostic (1.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.03e-1)" "unprognostic (3.38e-2)" 4.0 7.2 9.9 2.7 10.0 2.2 4.6 10.0 12.1 4.9 6.9 5.2 1.8 5.8 8.1 3.8 9.8 3.9 8.5 11.0 10.1 5.3 1.7 3.8 3.8 7.6 8.3 5.4 3.6 5.9 9.7 2.7 8.3 4.9 3.1 11.3 4.7 3.8 3.4 4.8 3.1 4.0 7.8 3.2 4.0 13.5 10.7 5.6 7.0 3.7 3.4 4.6 4.8 8.8 0.9 0.8 17.5 12.3 18.8 17.1 0.5 5.8 6.5 3.3 5.6 0.0 2.6 1.0 3.5 10.6 1.8 0.6 1.5 1.5 3.4 1.4 2.7 1.7 0.6 1.6 13.3 4.5 2.2 13.5 21.8 2.0 5.4 14.3 10.7 14.2 0.5 10.8 12.3 5.5 4.3 7.4 2.2 4.6 1.2 9.3 9.2 0.2 6.1 1.5 4.0 8.2 4.6 2.4 16.0 9.1 6.3 7.4 10.1 3.4 2.3 7.7 0.8 3.6 0.7 0.5 9.1 8.2 6.2 4.7 5.5 6.7 10.6 5.9 11.2 2.7 9.8 12.3 9.8 4.5 8.4 10.5 1.2 10.5 4.8 6.5 6.4 5.7 9.9 10.0 10.0 12.1 11.0 10.1 7.6 8.3 8.3 7.8 10.7 8.8 3.8 0.0 2.7 3.9 1.5 2.3 2.4 5.9 2.8 5.1 6.2 7.2 5.0 1.5 5.6 1.8 6.2 2.7 3.4 1.1 15.6 7.3 39.9 12.8 6.6 4.1 0.0 2.1 8.8 4.9 1.3 5.9 3.6 4.1 1.3 9.2 5.7 0.3 4.9 5.0 9.0 3.0 16.2 4.0 2.2 18.2 4.1 2.4 8.8 3.7 4.4 6.4 7.2 4.0 3.8 4.5 6.6 6.0 0.5 2.4 0.6 7.2 20.0 11.5 6.6 5.6 3.7 10.7 32.6 4.8 2.7 0.7 5.9 5.5 1.8 2.2 BIK NBK ENSG00000100290 "BCL2 interacting killer" Q13323 22 43110750-43129712 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 329.3;Club cells: 215.6;Ionocytes: 443.5;Paneth cells: 140.5;Respiratory ciliated cells: 204.1;Urothelial cells: 175.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 72.9;plasmacytoid DC: 58.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 89.9;CAPAN-2: 44.3;Daudi: 44.2;U-698: 172.1" "Not detected" "Not detected" HPA051360 Approved NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA051360: AB_2681453" "unprognostic (1.18e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.09e-1)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.86e-3)" "unprognostic (3.27e-1)" "unprognostic (2.71e-2)" "unprognostic (4.36e-3)" "unprognostic (2.36e-1)" "prognostic favorable (7.45e-5)" "unprognostic (1.38e-2)" "unprognostic (2.56e-1)" "unprognostic (4.08e-2)" "unprognostic (3.04e-1)" 0.2 2.3 0.2 4.1 0.4 4.1 4.9 0.7 0.3 2.8 0.0 8.5 3.6 0.2 1.2 11.3 3.0 3.1 0.3 0.5 0.0 3.8 0.5 1.4 11.6 0.0 0.0 0.3 2.5 1.6 1.0 0.1 0.1 11.4 5.2 0.2 17.5 0.5 0.0 3.5 5.3 0.2 0.0 2.9 13.4 2.0 0.1 1.4 1.8 0.1 11.2 2.6 6.5 0.0 89.9 0.7 0.2 0.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 28.8 44.3 44.2 4.2 0.0 0.9 19.5 4.8 1.9 0.0 0.7 6.7 0.1 0.6 4.9 0.7 21.2 4.1 0.0 8.8 0.0 0.0 0.3 0.2 9.5 0.3 2.0 0.0 22.9 16.9 28.9 6.7 24.2 7.3 0.2 0.1 20.6 0.9 2.6 1.7 0.0 3.1 8.2 6.5 3.1 1.6 28.9 0.8 0.1 2.4 0.2 1.0 10.4 17.1 172.1 0.0 2.2 0.2 1.8 2.9 72.9 2.7 0.7 4.3 17.1 9.5 4.2 10.4 11.7 6.4 3.5 11.3 0.9 0.8 58.6 7.1 6.3 0.2 0.4 0.7 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 4.2 0.0 9.3 12.6 32.7 329.3 3.4 0.0 39.7 24.1 0.7 17.2 215.6 7.3 0.0 1.4 7.9 43.0 7.9 62.2 0.3 17.7 0.8 2.3 50.6 5.7 0.3 16.2 1.2 0.9 90.7 9.1 0.0 0.1 5.3 0.7 0.9 0.0 0.2 52.9 443.5 1.4 4.8 0.4 0.0 4.0 35.6 0.0 6.4 0.0 1.0 0.0 0.1 105.2 140.5 0.7 79.7 53.1 10.2 15.7 204.1 0.0 0.0 0.0 14.9 0.2 11.0 16.1 11.8 1.0 12.9 0.3 53.9 175.3 MCAT "fabD, FASN2C, MCT, MCT1, MT, NET62" ENSG00000100294 "Malonyl-CoA-acyl carrier protein transacylase" Q8IVS2 22 43132209-43143398 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003122, HPA035471" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "HPA003122: AB_2666795, HPA035471: AB_10670590" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.39e-2)" "prognostic favorable (5.53e-4)" "unprognostic (3.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-3)" "unprognostic (4.71e-2)" "unprognostic (5.13e-2)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" "unprognostic (9.86e-2)" "prognostic favorable (2.18e-4)" "prognostic favorable (3.89e-4)" "unprognostic (3.67e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-1)" 10.2 21.6 11.8 5.7 12.5 9.0 11.7 11.1 14.4 9.2 17.1 12.5 6.7 11.5 9.9 15.5 14.3 6.6 18.2 13.6 12.5 25.1 22.7 8.7 5.1 11.9 11.6 11.3 15.0 17.6 16.6 4.6 12.2 13.5 7.1 7.2 13.3 6.6 21.9 14.9 8.6 5.8 10.6 8.1 14.8 17.1 12.0 7.8 13.1 10.1 6.1 10.8 10.3 11.0 14.1 18.2 12.6 22.3 10.4 11.0 12.9 15.4 13.6 20.3 18.8 18.3 14.1 23.6 15.5 11.5 11.5 23.3 24.1 20.4 15.1 8.2 71.3 8.8 21.6 20.6 16.6 42.3 10.3 8.3 19.5 19.9 15.7 11.8 14.7 14.1 21.1 9.4 10.1 26.0 19.9 46.0 12.3 19.8 31.8 26.0 12.4 37.7 25.7 12.1 16.6 8.8 16.6 32.0 24.3 5.7 16.5 27.1 8.9 8.8 17.4 19.2 22.0 16.6 18.4 17.1 19.0 16.0 10.8 0.0 11.4 0.8 8.8 11.1 11.5 9.4 9.7 11.4 16.4 12.4 10.9 7.9 2.9 14.5 6.9 16.2 7.0 7.3 11.8 12.5 11.1 14.4 13.6 12.5 11.9 11.6 12.2 10.6 12.0 11.0 8.0 6.4 6.8 3.9 6.9 17.8 12.3 19.6 5.7 11.2 13.6 11.4 9.5 31.5 10.6 20.2 0.0 18.7 5.7 12.3 50.9 32.0 23.4 28.5 8.3 9.4 14.5 17.9 3.6 21.8 11.9 8.8 12.2 9.2 3.8 10.8 17.5 22.3 15.5 6.7 3.7 14.7 14.2 6.3 4.3 11.8 7.5 6.1 7.2 0.0 8.2 12.5 4.1 1.5 2.1 23.7 15.2 16.6 5.6 17.3 12.5 94.3 27.7 9.6 19.7 11.2 10.0 30.0 11.7 9.0 21.0 9.2 4.8 30.5 22.4 11.5 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 104.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.3;Paneth cells: 56.9;Squamous epithelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB046029: AB_11128395, HPA003054: AB_2666770" "unprognostic (2.45e-2)" "unprognostic (3.47e-2)" "unprognostic (7.37e-3)" "unprognostic (5.40e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (5.81e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-3)" "unprognostic (1.40e-1)" "unprognostic (6.66e-2)" "unprognostic (2.81e-2)" 13.9 28.1 8.7 16.6 8.5 26.2 13.0 10.0 15.1 25.8 1.8 35.6 24.4 13.9 3.6 104.5 13.9 18.5 10.2 9.5 9.7 9.0 21.0 9.3 11.2 16.2 8.7 23.7 19.2 9.4 14.7 7.2 15.8 15.2 19.5 4.7 21.9 6.8 12.6 36.8 22.9 7.1 6.5 10.7 33.4 25.7 8.1 8.0 9.1 7.9 12.9 15.5 37.0 9.1 113.2 46.7 18.5 45.9 27.8 19.0 59.7 36.3 12.8 34.1 17.8 76.2 62.7 107.9 43.0 30.3 16.7 78.8 77.3 66.5 8.7 13.6 123.3 26.5 73.6 66.4 43.5 120.2 26.4 30.2 79.3 40.8 43.4 18.3 36.5 52.1 166.1 24.8 16.1 104.4 84.1 65.2 67.4 78.9 46.1 84.4 63.5 155.6 28.7 36.6 56.2 23.2 77.1 111.2 41.6 8.4 44.0 52.9 35.2 22.7 31.7 44.1 51.4 41.6 55.4 81.0 25.7 60.8 31.4 0.0 2.3 0.3 2.6 1.2 2.5 1.8 2.5 1.9 1.8 1.1 2.4 1.7 0.6 2.3 1.7 1.6 1.8 1.9 8.7 8.5 10.0 15.1 9.5 9.7 16.2 8.7 15.8 6.5 8.1 9.1 3.7 6.4 6.7 3.6 6.4 11.2 11.4 11.0 17.1 8.5 13.5 9.9 4.5 17.2 7.6 7.3 4.2 8.8 3.2 56.3 5.9 14.2 1.0 5.0 9.5 5.8 9.1 39.1 8.0 8.6 19.0 6.0 34.1 14.7 0.0 14.3 8.2 35.0 9.8 0.0 8.5 30.6 10.2 14.2 2.9 2.6 8.7 7.5 10.6 1.9 7.7 4.2 4.1 3.0 2.2 25.8 56.9 17.0 9.4 28.7 32.1 8.3 5.0 5.6 0.0 5.2 7.2 2.0 12.2 60.2 18.2 4.1 5.9 13.4 39.9 13.7 SCUBE1 ENSG00000159307 "Signal peptide, CUB domain and EGF like domain containing 1" Q8IWY4 22 43197280-43343372 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 26.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 13.3;Granulosa cells: 37.2;Peritubular cells: 45.5;Theca cells: 14.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HMC-1: 49.8;THP-1: 20.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003190 Approved "Secreted to blood" NA NA 2170000 190000 "Cluster 72: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "HPA003190: AB_1079882" "unprognostic (5.29e-2)" "unprognostic (7.15e-6)" "unprognostic (6.03e-3)" "unprognostic (8.33e-2)" "unprognostic (3.65e-1)" "unprognostic (4.55e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "unprognostic (1.10e-1)" "unprognostic (1.99e-1)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-2)" "unprognostic (1.02e-2)" "unprognostic (2.70e-1)" "unprognostic (2.30e-1)" "unprognostic (6.87e-3)" 1.8 6.1 0.8 0.8 1.1 0.1 1.2 0.1 1.4 0.9 4.1 3.8 5.9 1.1 0.1 3.6 1.2 0.8 0.2 0.6 3.8 3.5 5.1 6.8 0.0 1.7 10.2 26.4 0.1 9.1 3.8 2.6 7.0 1.9 2.0 0.4 3.6 0.5 9.6 0.6 7.7 0.5 0.3 5.7 7.0 7.1 1.2 0.1 3.1 1.9 0.0 3.3 0.7 0.4 0.0 0.0 2.2 7.8 0.0 0.0 4.9 0.0 0.0 0.0 0.1 0.0 3.5 0.0 0.1 0.1 0.3 0.1 0.7 0.0 0.0 0.1 0.7 0.0 0.1 0.7 0.2 0.2 49.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.0 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.2 0.0 0.1 0.0 0.3 0.1 20.4 0.0 0.3 0.2 0.6 0.0 2.1 4.3 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.1 1.4 0.6 3.8 1.7 10.2 7.0 0.3 1.2 0.4 0.2 9.6 1.7 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.9 0.1 1.4 0.0 0.6 0.0 0.0 0.2 0.2 0.0 1.9 0.1 3.0 1.3 1.2 1.3 0.0 0.0 0.4 0.0 13.3 2.6 0.5 3.4 1.3 37.2 0.4 1.9 0.8 0.0 0.3 0.2 0.0 0.0 0.4 4.6 7.8 0.2 0.0 0.0 0.1 4.1 0.0 0.0 0.3 0.1 0.0 45.5 0.4 0.0 0.0 0.4 0.7 0.2 0.0 0.4 1.2 3.8 2.0 0.0 0.1 0.4 2.8 14.3 0.0 0.1 MPPED1 "239AB, C22orf1, FAM1A" ENSG00000186732 "Metallophosphoesterase domain containing 1" O15442 22 43411196-43507848 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "brain: 58.6;liver: 24.5" "Group enriched" "Detected in some" 5 "Excitatory neurons: 69.4;Inhibitory neurons: 68.6" "Cancer enhanced" "Detected in some" "liver cancer: 1.6" "Group enriched" "Detected in many" 214 "amygdala: 18.6;basal ganglia: 30.2;cerebral cortex: 58.6;hippocampal formation: 24.2;white matter: 22.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 5.3;SCLC-21H: 2.3" "Group enriched" "Detected in all" 5 "amygdala: 105.7;basal ganglia: 66.2;cerebral cortex: 163.5;hippocampal formation: 174.4;white matter: 106.3" "Group enriched" "Detected in all" 6 "cerebral cortex: 95.0;hippocampal formation: 83.0" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.15e-1)" "unprognostic (4.29e-1)" "unprognostic (8.17e-2)" "unprognostic (4.81e-2)" "unprognostic (9.62e-2)" "unprognostic (1.03e-1)" "unprognostic (7.47e-2)" "unprognostic (2.04e-1)" "unprognostic (3.19e-1)" "unprognostic (4.46e-4)" "unprognostic (1.09e-1)" "unprognostic (4.32e-3)" "unprognostic (1.30e-1)" "unprognostic (2.87e-1)" "unprognostic (6.92e-3)" 0.0 0.1 18.6 0.0 30.2 0.0 0.1 0.0 58.6 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 24.2 0.0 0.1 24.5 0.0 0.0 0.0 0.0 1.5 0.0 0.0 1.7 0.0 0.0 0.9 0.0 0.5 1.4 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.8 1.9 0.0 0.4 0.0 0.0 0.0 0.3 0.3 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 18.6 30.2 0.0 58.6 24.2 0.0 0.0 0.0 0.0 0.1 0.0 22.5 0.1 0.0 0.0 3.6 0.0 0.5 0.1 0.0 0.0 2.7 0.0 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 69.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 68.6 0.2 0.0 0.6 0.0 2.7 0.6 0.0 0.0 4.7 0.0 0.5 0.0 2.0 13.3 0.0 0.0 7.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EFCAB6 "dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672" ENSG00000186976 "EF-hand calcium binding domain 6" Q5THR3 22 43528744-43812337 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.3" "Group enriched" "Detected in many" 8 "Early spermatids: 286.6;Late spermatids: 473.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.1;RPTEC TERT1: 1.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA003098 Uncertain Nucleoplasm NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "HPA003098: AB_1079087" "unprognostic (1.85e-1)" "unprognostic (8.85e-3)" "unprognostic (4.45e-2)" "unprognostic (1.04e-5)" "unprognostic (1.00e-1)" "unprognostic (4.25e-2)" "unprognostic (4.96e-2)" "unprognostic (8.82e-3)" "unprognostic (2.02e-1)" "unprognostic (1.54e-1)" "unprognostic (1.91e-3)" "unprognostic (3.66e-2)" "unprognostic (1.71e-3)" "unprognostic (4.54e-1)" "unprognostic (1.82e-1)" "unprognostic (1.65e-3)" "unprognostic (1.33e-2)" 0.4 0.8 0.9 0.1 0.9 0.0 1.1 0.0 0.7 1.1 6.8 0.5 0.3 1.2 2.1 0.4 7.7 0.5 0.4 0.9 1.4 1.4 0.4 1.2 0.2 2.2 3.2 1.4 1.2 2.4 2.0 0.2 1.5 0.9 0.2 3.1 0.8 1.1 0.2 0.4 0.2 0.5 1.4 0.1 0.9 24.3 1.4 0.2 3.1 0.2 0.1 0.4 0.4 0.4 0.1 0.3 0.4 0.7 0.6 2.1 0.0 0.5 0.4 0.1 0.2 0.0 0.1 0.0 0.3 0.2 0.8 0.6 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.7 0.8 0.5 0.1 0.5 0.1 0.2 0.0 0.0 0.3 1.4 0.0 0.1 0.6 0.4 0.2 0.0 0.0 0.0 1.5 0.3 0.9 0.3 1.4 0.0 0.7 0.3 0.2 0.0 0.1 0.3 0.1 0.5 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.0 0.7 0.9 1.4 2.2 3.2 1.5 1.4 1.4 0.4 0.2 3.2 1.8 18.9 0.5 0.3 0.9 1.0 2.2 3.0 1.2 1.0 1.7 0.0 2.3 0.0 6.2 0.0 0.0 0.4 0.0 0.9 286.6 21.8 1.5 0.4 0.0 0.0 46.0 0.7 0.1 1.3 1.1 1.9 1.3 1.5 0.4 0.4 0.3 6.7 36.8 0.4 2.0 0.3 0.3 473.7 3.1 0.3 0.0 15.9 0.6 1.7 0.0 15.1 10.2 1.0 0.1 1.5 0.2 0.5 0.1 1.1 20.4 12.5 6.6 1.3 0.8 24.1 4.7 0.8 0.1 0.1 0.1 1.4 0.4 0.3 SULT4A1 "hBR-STL-1, SULTX3" ENSG00000130540 "Sulfotransferase family 4A member 1" Q9BR01 22 43824509-43862513 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "brain: 90.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 23.0;Early spermatids: 23.7;Excitatory neurons: 53.1;Horizontal cells: 23.5;Inhibitory neurons: 55.2;Late spermatids: 29.4;Rod photoreceptor cells: 19.5" "Cancer enhanced" "Detected in many" "testis cancer: 6.3" "Region enhanced" "Detected in many" "cerebral cortex: 90.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003129 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA003129: AB_1080130" "unprognostic (2.61e-3)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "unprognostic (6.30e-2)" "unprognostic (6.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.63e-1)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (2.48e-4)" "unprognostic (1.91e-2)" "unprognostic (6.10e-2)" "unprognostic (7.59e-4)" "unprognostic (7.89e-2)" "unprognostic (1.22e-1)" "unprognostic (8.20e-3)" "unprognostic (8.34e-3)" 0.0 2.7 22.3 0.3 23.2 0.0 0.0 1.6 90.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 22.2 21.7 0.1 0.0 0.0 0.0 9.6 0.0 0.0 0.2 0.0 2.5 0.0 8.0 0.0 0.2 2.2 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.4 0.8 5.9 0.0 0.0 0.0 0.0 0.0 0.3 25.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.3 23.2 1.6 90.2 22.2 21.7 9.6 0.0 8.0 0.0 5.9 25.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.3 0.0 23.0 0.2 0.5 1.4 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 23.7 1.1 1.3 0.4 0.0 0.0 53.1 0.0 0.0 0.4 0.0 3.7 0.0 1.9 0.0 0.0 0.1 23.5 55.2 0.0 0.0 0.0 0.0 29.4 0.0 0.1 0.0 10.3 0.0 4.0 0.0 8.0 6.2 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 19.5 0.0 0.0 0.2 3.0 5.7 0.0 0.0 0.0 0.0 3.2 0.0 0.0 PNPLA5 "dJ388M5.4, GS2L" ENSG00000100341 "Patatin like phospholipase domain containing 5" Q7Z6Z6 22 43879678-43892013 "Enzymes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4;epididymis: 1.7;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.2;Inhibitory neurons: 2.1;Late spermatids: 2.1" "Cancer enriched" "Detected in single" 4 "thyroid cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.4;RPMI-8226: 2.7" "Not detected" "Not detected" "HPA050409, HPA054211" Uncertain NA NA "Cluster 34: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "HPA050409: AB_2681118, HPA054211: AB_2682418" "unprognostic (6.69e-5)" "unprognostic (3.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-2)" "unprognostic (3.33e-3)" "unprognostic (1.05e-1)" "unprognostic (1.50e-1)" "unprognostic (4.31e-2)" 0.0 0.0 0.8 0.1 3.4 0.3 0.3 0.2 2.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.9 0.0 0.0 1.2 0.6 0.0 0.0 0.0 0.9 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 0.0 0.1 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.1 2.7 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.8 3.4 0.2 2.3 1.4 0.5 1.2 0.6 0.4 0.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PNPLA3 "adiponutrin, ADPN, C22orf20, dJ796I17.1, FLJ22012, iPLA2epsilon" ENSG00000100344 "Patatin like phospholipase domain containing 3" Q9NST1 22 43923792-43964488 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 31.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 35.9;Cone photoreceptor cells: 18.8;Hepatocytes: 42.3;Rod photoreceptor cells: 37.3" "Cancer enhanced" "Detected in many" "liver cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 16.7;LHCN-M2: 19.3" "Region enhanced" "Detected in many" "cerebellum: 12.2" "Not detected" "Not detected" HPA058058 Approved Approved Nucleoli,Mitochondria,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoli "Mitochondria, Cytosol" "HPA058058: AB_2683590" "unprognostic (4.74e-3)" "unprognostic (4.52e-2)" "unprognostic (1.76e-1)" "unprognostic (2.31e-1)" "unprognostic (1.36e-2)" "unprognostic (1.89e-1)" "unprognostic (8.93e-2)" "unprognostic (1.02e-1)" "unprognostic (2.63e-1)" "unprognostic (2.93e-1)" "unprognostic (2.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-3)" "unprognostic (2.52e-3)" "unprognostic (5.91e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-1)" 2.6 0.2 0.6 0.5 0.8 0.1 1.6 0.1 1.2 0.6 5.9 0.1 0.8 0.3 0.1 0.2 0.9 0.4 0.2 1.2 0.7 4.5 31.0 0.8 0.3 1.7 1.8 0.3 0.0 0.2 0.0 0.3 2.0 0.0 0.1 6.4 0.7 0.0 1.7 5.8 0.5 0.0 0.2 0.4 0.2 0.4 1.3 0.1 0.1 0.1 0.2 0.0 0.3 0.6 5.1 1.6 16.7 6.8 4.6 5.2 0.5 3.1 1.8 4.1 8.8 5.0 9.0 0.0 2.5 5.2 2.4 4.3 10.6 5.0 3.4 0.0 0.9 0.3 4.5 9.4 7.5 0.0 0.3 6.0 3.8 13.2 0.6 7.0 0.5 0.2 0.0 0.0 19.3 0.7 0.3 0.0 11.5 0.6 0.0 0.1 8.9 0.2 1.7 0.2 1.5 0.1 3.4 1.4 4.8 2.9 5.3 5.8 0.6 1.6 4.9 0.1 0.1 0.1 0.0 0.0 14.3 0.1 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.8 0.1 1.2 1.2 0.7 1.7 1.8 2.0 0.2 1.3 0.6 0.4 0.0 0.0 4.2 0.2 0.4 0.5 2.4 0.0 35.9 0.5 0.1 1.3 10.0 1.4 0.0 18.8 0.0 0.2 0.2 0.0 0.4 0.0 1.5 0.5 0.4 1.8 0.0 1.9 0.0 0.1 0.5 0.0 3.6 0.0 1.9 0.7 42.3 0.7 0.0 1.2 0.8 0.0 2.8 0.3 0.3 0.3 0.9 1.8 0.0 0.0 1.1 0.0 0.0 0.8 2.6 0.0 0.7 0.0 0.7 0.4 5.0 0.1 37.3 0.0 1.0 0.8 0.6 0.6 0.0 0.1 0.0 0.2 1.6 0.4 0.4 SAMM50 "CGI-51, OMP85, SAM50, TOB55, TRG-3, YNL026W" ENSG00000100347 "SAMM50 sorting and assembly machinery component" Q9Y512 22 43955442-44010531 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 240.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034537 Enhanced Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA034537: AB_10602794" "unprognostic (2.92e-1)" "unprognostic (1.01e-1)" "unprognostic (1.95e-3)" "prognostic favorable (2.63e-7)" "unprognostic (2.43e-3)" "unprognostic (2.28e-1)" "unprognostic (5.28e-3)" "unprognostic (1.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.42e-1)" "unprognostic (3.52e-1)" "prognostic favorable (4.43e-8)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.60e-1)" 41.7 50.6 26.1 27.0 27.0 32.5 35.8 29.8 30.6 43.4 31.1 35.6 50.8 27.0 29.3 31.7 41.9 29.3 65.5 27.1 29.2 48.8 37.2 22.2 34.6 29.8 28.5 40.0 33.3 114.4 24.4 20.1 30.4 26.5 35.5 25.5 35.2 25.1 240.4 35.9 38.3 27.7 27.0 24.4 43.8 26.1 28.5 34.4 28.1 177.0 37.0 27.9 24.0 28.0 64.6 59.8 57.1 69.5 72.2 75.9 79.8 61.7 65.7 89.1 76.4 86.1 46.0 105.9 44.3 70.8 51.4 75.6 85.4 82.6 79.7 29.4 105.3 57.5 73.9 102.6 50.4 184.0 83.1 88.3 64.7 77.0 35.5 62.3 93.1 49.9 49.9 34.0 80.9 91.7 72.6 72.0 56.0 77.4 70.9 83.8 61.8 85.9 74.4 81.0 34.1 55.4 68.3 72.2 104.1 60.4 67.7 59.8 57.7 57.3 68.8 53.6 51.2 50.1 74.4 82.1 72.0 66.3 58.7 47.5 39.2 46.9 39.8 39.0 55.4 55.1 36.6 40.5 67.7 51.0 37.8 36.0 6.1 39.1 31.8 26.7 45.7 40.2 26.1 27.0 29.8 30.6 27.1 29.2 29.8 28.5 30.4 27.0 28.5 28.0 52.9 35.3 18.9 10.4 31.6 20.6 27.0 72.0 30.7 20.1 32.1 40.9 68.6 18.6 39.5 9.2 8.4 41.6 31.7 36.1 60.7 47.2 40.3 47.3 24.9 35.1 18.6 51.4 12.0 55.5 54.1 24.6 42.3 32.7 27.3 43.9 30.0 41.8 51.1 32.0 12.7 35.2 46.8 28.6 20.5 50.1 26.1 25.0 16.0 12.2 41.4 32.8 33.0 9.5 9.1 43.7 34.5 30.5 31.0 16.2 82.4 116.8 39.9 30.1 19.7 23.2 33.4 45.8 31.2 34.3 22.6 20.5 28.5 69.9 59.8 19.3 PARVB CGI-56 ENSG00000188677 "Parvin beta" Q9HBI1 22 43999211-44172939 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 195.9;tongue: 170.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 113.2;Hofbauer cells: 90.6;Macrophages: 78.7" "Cancer enhanced" "Detected in all" "melanoma: 20.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 158.0;RPMI-8226: 159.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062601, HPA072217" Enhanced Approved Cytosol NA NA 24000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "HPA062601: AB_2684803, HPA072217: " "unprognostic (2.41e-1)" "unprognostic (5.52e-3)" "unprognostic (1.66e-1)" "unprognostic (3.83e-2)" "unprognostic (2.10e-3)" "unprognostic (7.65e-3)" "unprognostic (1.28e-1)" "unprognostic (1.73e-2)" "unprognostic (2.28e-1)" "unprognostic (6.46e-2)" "unprognostic (1.03e-2)" "unprognostic (6.45e-2)" "unprognostic (1.28e-2)" "unprognostic (4.87e-3)" "unprognostic (3.19e-2)" "unprognostic (4.19e-2)" "unprognostic (7.05e-3)" 42.6 30.7 26.7 21.3 19.4 43.4 33.0 18.7 24.3 21.8 22.6 21.8 7.4 22.2 13.5 11.9 19.2 10.7 86.9 34.1 24.7 23.0 14.4 29.7 19.2 23.3 25.7 27.1 11.9 18.5 24.3 21.4 26.9 17.0 8.6 10.5 11.4 13.7 195.9 14.2 18.6 22.9 20.8 35.3 15.0 6.6 28.3 9.4 12.8 170.6 16.1 23.9 16.7 19.7 23.5 27.7 0.4 19.1 28.1 35.5 0.1 32.4 20.1 20.9 15.6 28.9 13.8 0.2 17.5 87.2 16.4 0.9 45.9 2.1 11.5 33.1 28.5 100.4 45.8 0.2 46.5 76.5 86.7 55.4 24.0 15.2 0.2 15.0 158.0 0.4 36.6 67.0 22.9 15.9 0.4 50.4 9.8 20.4 18.7 0.2 0.8 159.5 0.5 0.6 24.6 17.1 8.6 1.6 84.9 3.3 15.9 30.7 99.2 19.0 20.0 29.4 3.4 16.2 15.3 0.7 82.8 22.1 106.0 6.9 6.8 1.6 1.0 7.1 1.6 6.2 1.7 1.5 7.2 6.4 0.4 0.9 4.7 0.8 2.9 14.9 2.4 9.5 26.7 19.4 18.7 24.3 34.1 24.7 23.3 25.7 26.9 20.8 28.3 19.7 70.3 0.0 10.6 5.2 48.2 5.2 3.4 1.3 4.0 11.2 8.3 9.4 55.0 4.3 0.9 1.8 16.7 1.0 29.0 0.3 27.4 1.5 6.6 8.0 12.6 63.7 1.2 113.2 15.1 3.1 10.8 18.4 4.1 11.7 64.7 20.2 53.2 12.5 90.6 6.7 12.5 0.7 6.1 49.7 39.5 21.6 19.9 78.7 19.6 28.1 44.7 8.9 9.2 2.5 5.9 4.7 0.0 10.9 58.1 5.1 0.0 30.0 3.8 15.2 6.6 18.2 14.2 1.9 5.8 0.7 4.4 1.8 16.7 2.3 0.6 1.5 PARVG ENSG00000138964 "Parvin gamma" Q9HBI0 22 44172956-44219533 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.7;lymphoid tissue: 30.1" "Cell type enhanced" "Detected in many" "B-cells: 56.9;dendritic cells: 51.7;granulocytes: 60.1;Hofbauer cells: 66.7;Kupffer cells: 87.3;Langerhans cells: 53.4;Macrophages: 91.9;monocytes: 62.0;T-cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HL-60: 116.4;NB-4: 44.9;THP-1: 64.7;U-937: 53.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031833, HPA031834" Uncertain NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "HPA031833: AB_2674063, HPA031834: AB_10601242" "unprognostic (9.83e-3)" "unprognostic (2.30e-2)" "unprognostic (2.06e-1)" "prognostic favorable (4.44e-6)" "unprognostic (2.79e-1)" "unprognostic (1.57e-2)" "unprognostic (2.14e-1)" "unprognostic (3.19e-2)" "unprognostic (7.02e-2)" "unprognostic (2.17e-1)" "unprognostic (3.87e-2)" "unprognostic (3.36e-1)" "prognostic unfavorable (3.43e-6)" "unprognostic (3.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.09e-1)" "unprognostic (9.89e-2)" 3.5 2.9 3.7 26.7 3.5 49.7 1.8 4.4 7.1 2.6 4.0 3.1 3.6 2.4 0.6 2.5 2.2 6.2 1.3 3.8 4.7 1.8 3.1 10.4 30.1 8.2 4.9 0.8 1.4 0.5 1.3 3.0 6.9 2.1 3.4 0.2 2.6 1.1 1.2 1.7 12.7 2.9 5.9 28.9 4.4 1.7 7.9 18.4 1.9 0.4 26.8 4.7 1.5 9.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 9.8 0.0 0.0 0.0 116.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 16.8 44.9 0.1 0.0 0.0 9.2 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 64.7 0.0 0.0 11.5 0.2 0.0 0.3 0.0 0.3 0.0 53.9 1.9 12.5 62.0 71.3 13.9 57.6 13.9 21.4 8.0 15.2 49.2 20.4 8.9 10.3 72.2 13.1 65.9 33.3 12.1 44.6 3.7 3.5 4.4 7.1 3.8 4.7 8.2 4.9 6.9 5.9 7.9 9.4 1.3 6.4 14.0 1.0 56.9 2.4 0.1 0.0 0.6 0.2 0.7 1.5 1.1 0.0 3.1 0.0 0.0 0.6 51.7 0.1 0.0 0.0 4.2 3.7 0.4 2.9 0.0 10.1 3.9 0.2 0.7 2.3 3.6 2.5 60.1 0.0 3.9 1.3 66.7 0.0 2.9 0.0 0.0 87.3 53.4 2.7 0.0 91.9 5.4 10.3 62.0 0.0 26.8 0.0 1.4 0.0 0.0 0.0 15.9 0.0 0.0 0.5 1.5 0.2 0.0 0.5 0.4 1.1 0.8 0.4 1.8 1.0 48.3 0.0 0.1 0.1 SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;endometrium 1: 33.6;smooth muscle: 29.3" "Cell type enriched" "Detected in single" 6 "Endometrial stromal cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SiHa: 36.2;U-2197: 80.8;U-87 MG: 46.3;WM-115: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (4.07e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (6.54e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.10e-3)" "unprognostic (1.93e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (1.51e-7)" "unprognostic (1.48e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-4)" "unprognostic (1.10e-4)" 1.0 1.8 18.6 1.2 17.2 0.0 0.2 0.0 21.4 16.6 0.0 18.7 1.9 33.6 0.4 1.6 4.5 3.1 0.9 18.0 15.3 0.5 0.1 0.3 0.4 10.8 17.8 1.0 0.8 0.1 2.6 0.5 2.4 3.7 2.0 5.6 0.3 11.0 0.0 0.7 2.4 29.3 0.3 0.1 1.6 1.1 43.2 2.6 0.4 0.1 0.7 11.9 5.2 2.8 0.0 0.3 3.5 1.2 0.0 0.0 0.0 1.0 2.3 2.4 1.4 0.0 0.0 0.0 0.0 2.3 14.5 0.0 5.0 0.3 0.3 0.0 2.3 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 1.8 11.2 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 3.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 12.9 0.0 36.2 0.1 0.2 0.4 0.0 0.3 0.1 13.1 2.0 80.8 0.5 0.0 0.0 0.0 46.3 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 17.2 0.0 21.4 18.0 15.3 10.8 17.8 2.4 0.3 43.2 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 RTL6 "dJ1033E15.2, DKFZp761O17121, LDOC1L, Mar6, Mart6, SIRH3" ENSG00000188636 "Retrotransposon Gag like 6" Q6ICC9 22 44492583-44498233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 11.1;Collecting duct cells: 12.9;Ductal cells: 8.4;Endometrial stromal cells: 12.9;Granulosa cells: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005697 Approved Approved "Nuclear speckles,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA005697: AB_1079244" "unprognostic (1.24e-1)" "unprognostic (1.55e-1)" "unprognostic (1.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.71e-3)" "unprognostic (1.57e-1)" "unprognostic (9.64e-3)" "unprognostic (5.40e-2)" "unprognostic (5.40e-2)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.57e-2)" "unprognostic (1.65e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" 10.6 12.1 21.3 7.2 19.2 3.2 8.9 15.1 18.9 11.2 8.3 12.5 8.8 15.7 12.1 8.2 16.6 11.0 15.3 20.1 17.4 9.3 3.2 9.4 6.3 18.8 20.0 19.2 11.0 17.8 8.7 5.1 17.1 9.8 9.1 9.6 7.2 13.6 15.5 3.4 8.4 16.9 18.8 7.5 9.7 11.2 21.9 14.2 10.2 18.0 4.8 10.4 5.4 17.2 13.8 18.9 23.9 31.9 18.3 14.8 6.3 17.9 21.1 24.6 19.2 6.3 8.0 0.0 10.9 33.5 18.5 11.8 16.3 17.7 15.1 6.5 31.8 0.0 35.8 0.0 22.6 1.8 8.7 16.2 16.8 22.5 17.3 33.4 22.3 21.6 7.8 0.1 16.9 24.3 44.4 4.1 14.7 15.1 20.0 12.1 12.7 0.0 21.1 15.8 25.6 30.0 29.2 14.0 18.1 11.5 14.0 19.3 23.1 19.2 25.7 25.7 14.5 8.3 3.5 0.0 28.5 4.5 29.2 0.0 0.7 0.0 1.8 0.3 1.9 0.0 1.0 1.5 0.5 0.0 0.4 1.0 0.0 0.4 0.4 0.0 0.2 1.1 21.3 19.2 15.1 18.9 20.1 17.4 18.8 20.0 17.1 18.8 21.9 17.2 5.8 0.0 5.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.1 6.5 0.0 0.0 2.5 12.9 0.0 2.9 4.8 0.0 0.0 8.4 0.0 7.4 12.9 4.0 0.0 0.0 0.0 6.5 2.7 3.5 0.0 8.1 0.0 13.2 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.7 0.0 0.0 5.7 7.3 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.2 1.8 5.2 0.0 0.0 PRR5 "FLJ20185k, PP610, Protor-1" ENSG00000186654 "Proline rich 5" P85299 22 44668547-44737681 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 91.3;NK-cells: 77.2;Proximal tubular cells: 55.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "monocytes: 19.1;T-cells: 28.6" "Cell line enhanced" "Detected in many" "U-266/70: 99.2;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054072 Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "HPA054072: AB_2682369" "unprognostic (2.63e-2)" "unprognostic (6.63e-3)" "unprognostic (2.61e-2)" "prognostic favorable (2.47e-5)" "unprognostic (1.83e-2)" "unprognostic (3.99e-2)" "unprognostic (7.52e-2)" "unprognostic (1.37e-1)" "unprognostic (8.98e-2)" "unprognostic (5.13e-2)" "unprognostic (1.34e-1)" "unprognostic (2.36e-1)" "unprognostic (1.65e-1)" "unprognostic (2.48e-3)" "unprognostic (1.55e-1)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" 16.2 2.4 7.2 3.2 7.7 7.2 12.2 5.9 11.3 8.4 11.9 6.0 8.6 3.8 2.1 7.6 4.3 2.9 3.5 7.9 9.7 11.5 18.5 3.5 3.9 8.1 8.2 4.0 6.2 2.3 16.1 4.5 8.5 7.9 2.4 0.4 5.7 3.8 0.8 7.4 9.4 1.1 5.9 20.5 5.2 5.1 10.5 2.3 4.5 1.2 2.5 6.9 7.1 5.8 8.1 9.6 2.0 6.8 0.2 0.3 25.0 7.0 6.2 4.2 3.4 24.4 3.4 0.0 5.2 8.2 4.9 7.2 2.1 7.1 0.7 0.2 19.9 15.9 1.3 28.5 5.8 2.9 5.8 2.9 7.9 0.4 2.2 1.0 0.2 3.7 10.1 0.5 0.9 21.4 1.1 4.6 1.3 11.4 1.4 0.7 4.5 14.5 1.4 3.8 7.0 1.0 1.9 11.4 9.5 5.5 5.3 2.8 0.0 0.1 11.0 1.0 0.1 99.2 31.3 0.2 0.0 6.4 0.8 0.5 0.3 0.1 24.8 3.4 28.6 1.6 8.3 18.8 0.7 0.9 3.5 13.0 0.6 5.6 19.1 0.4 14.8 6.8 7.2 7.7 5.9 11.3 7.9 9.7 8.1 8.2 8.5 5.9 10.5 5.8 6.0 0.0 3.9 11.4 9.2 8.3 12.0 2.1 4.0 0.7 13.6 13.2 2.0 10.0 2.3 5.5 0.0 32.1 50.3 20.5 5.9 5.2 0.5 4.4 5.4 12.5 9.6 91.3 2.0 7.9 3.3 23.2 8.2 4.7 7.6 5.4 21.4 19.9 32.1 0.0 1.8 22.8 2.0 13.5 8.2 0.5 5.3 7.7 8.8 3.7 3.0 6.0 77.2 1.0 0.2 8.4 7.6 3.8 29.0 24.2 50.9 55.2 1.4 1.5 0.0 11.4 5.3 0.3 20.4 8.0 8.5 44.1 37.1 51.8 25.5 13.5 PRR5-ARHGAP8 ENSG00000248405 "PRR5-ARHGAP8 readthrough" 22 44702233-44862706 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Astrocytes: 4.9;Collecting duct cells: 5.5;Pancreatic endocrine cells: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.0;CACO-2: 2.1;HEK 293: 2.7;MCF7: 2.1;U-266/70: 6.8" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 1: Pancreatic cells - Digestion" "unprognostic (1.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" "unprognostic (5.52e-2)" "unprognostic (3.65e-2)" "unprognostic (6.61e-3)" "unprognostic (3.29e-2)" "unprognostic (1.77e-2)" "unprognostic (2.35e-1)" "unprognostic (2.75e-2)" "unprognostic (2.53e-2)" "unprognostic (6.47e-3)" "unprognostic (9.28e-8)" "unprognostic (8.64e-2)" "unprognostic (9.91e-2)" "unprognostic (2.41e-2)" "unprognostic (3.45e-1)" 0.5 0.0 0.0 0.0 0.1 0.2 0.9 0.0 0.3 0.2 0.2 0.7 0.5 0.1 0.1 0.6 0.6 0.5 0.0 0.1 0.1 1.5 0.2 0.4 0.2 0.1 0.2 0.0 0.8 0.4 0.5 0.2 0.1 0.8 0.3 0.0 0.7 0.8 0.0 0.6 0.4 0.0 0.0 1.0 0.4 0.1 0.1 0.0 1.4 0.0 0.2 0.3 0.3 0.1 1.3 0.0 0.0 0.0 0.0 0.0 3.0 0.0 1.3 0.0 0.0 2.1 0.3 0.0 0.1 0.0 0.0 0.7 0.5 1.4 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.6 0.1 0.7 0.2 0.0 0.0 0.9 0.0 0.1 1.3 0.0 0.0 0.0 0.3 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 3.2 1.5 4.9 0.0 0.4 1.0 0.2 0.0 0.0 0.6 0.3 0.1 0.0 0.8 5.5 0.0 0.7 0.1 0.6 1.9 1.9 0.0 0.6 0.1 0.0 1.2 0.0 0.9 0.6 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.9 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.3 0.1 0.2 0.5 0.9 ARHGAP8 "BPGAP1, FLJ20185" ENSG00000241484 "Rho GTPase activating protein 8" P85298 22 44752558-44862788 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 20.5;Cytotrophoblasts: 26.9;Ductal cells: 25.6;Pancreatic endocrine cells: 30.5;Urothelial cells: 20.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 26.9;BEWO: 47.5;CACO-2: 30.9;HEK 293: 43.6;MCF7: 44.9;SK-BR-3: 40.1" "Not detected" "Not detected" HPA069694 Approved NA No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "HPA069694: AB_2686173" "unprognostic (4.14e-1)" "unprognostic (1.21e-2)" "unprognostic (6.88e-2)" "unprognostic (8.07e-2)" "unprognostic (1.24e-1)" "unprognostic (1.19e-1)" "unprognostic (6.49e-2)" "unprognostic (5.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (8.78e-3)" "unprognostic (9.58e-2)" "unprognostic (7.65e-6)" "unprognostic (8.59e-2)" "unprognostic (3.29e-1)" "unprognostic (2.32e-2)" "unprognostic (2.22e-2)" 1.0 0.4 0.4 1.2 0.2 0.6 9.5 1.1 1.0 3.0 4.2 10.0 1.7 1.6 11.4 7.5 6.8 4.3 0.1 0.4 0.1 28.1 1.1 4.4 0.7 0.2 0.1 0.3 10.3 5.6 6.4 7.4 0.4 13.5 7.1 0.3 23.2 8.3 0.1 2.0 3.6 0.3 0.1 9.0 6.5 3.3 0.4 0.5 17.5 0.0 1.1 2.0 2.9 0.2 26.9 0.4 0.4 0.2 0.0 0.4 47.5 0.2 3.1 0.0 0.2 30.9 13.5 0.2 1.6 0.0 0.4 19.1 8.5 21.9 0.2 0.1 43.6 0.0 0.9 0.4 0.1 0.1 0.4 0.2 9.3 0.2 0.4 0.6 0.1 0.5 0.9 0.7 0.1 44.9 0.1 0.2 6.7 19.3 0.0 0.0 0.1 0.4 11.6 17.9 2.7 0.1 0.0 40.1 0.9 9.9 17.5 0.3 0.4 0.0 1.5 0.1 0.2 3.9 0.2 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.2 1.1 1.0 0.4 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.1 3.2 12.5 0.0 0.5 0.6 20.5 5.9 3.4 0.4 8.9 2.4 0.8 4.3 9.1 18.4 4.2 26.9 0.7 8.6 0.0 25.6 2.3 4.1 1.0 1.1 7.2 0.0 0.0 10.8 2.1 1.3 7.1 12.3 0.0 0.5 0.4 0.0 3.3 0.0 0.0 11.7 12.2 1.0 0.4 3.2 0.3 0.6 0.0 0.0 0.1 0.7 5.2 0.0 0.0 30.5 12.1 0.4 0.6 20.0 1.2 2.0 4.1 0.7 0.0 1.7 0.7 0.1 3.9 6.0 0.3 7.0 1.0 6.9 17.0 20.8 PHF21B "BHC80L, FLJ34161, PHF4" ENSG00000056487 "PHD finger protein 21B" Q96EK2 22 44881162-45010005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.9" "Cell type enhanced" "Detected in some" "Astrocytes: 96.6;Cone photoreceptor cells: 22.9;Horizontal cells: 28.6;Late spermatids: 41.9;Oligodendrocyte precursor cells: 29.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in some" "glioma: 1.9;prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 11.2;AN3-CA: 10.0;JURKAT: 8.8;SCLC-21H: 8.7;SH-SY5Y: 37.5;U-2 OS: 8.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053834, HPA074665" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA053834: AB_2682276, HPA074665: " "unprognostic (1.04e-1)" "unprognostic (7.76e-2)" "unprognostic (2.00e-1)" "unprognostic (7.44e-2)" "unprognostic (1.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.55e-1)" "unprognostic (3.83e-3)" "unprognostic (1.86e-3)" "unprognostic (2.02e-1)" "unprognostic (9.35e-2)" "unprognostic (2.27e-1)" "unprognostic (4.08e-2)" "unprognostic (1.22e-1)" 0.2 1.2 6.7 0.1 7.9 0.0 0.4 4.8 6.1 9.0 1.5 0.2 0.1 3.2 0.4 0.4 2.5 0.1 0.9 5.1 5.1 2.6 0.0 0.1 0.0 8.5 8.3 4.0 0.5 0.9 18.9 0.0 5.2 5.2 0.0 6.1 0.3 0.5 0.2 0.1 0.2 0.7 4.4 0.1 0.6 5.4 6.8 0.2 2.0 0.3 0.0 0.2 3.2 4.7 0.0 0.0 11.2 10.0 0.0 0.0 0.7 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 2.0 0.1 2.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.3 0.6 0.0 0.0 8.8 0.0 0.0 0.1 0.9 1.3 0.0 6.7 0.0 0.4 0.0 2.6 0.2 0.0 0.1 8.7 37.5 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.5 8.5 0.0 0.2 0.4 0.0 5.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 7.9 4.8 6.1 5.1 5.1 8.5 8.3 5.2 4.4 6.8 4.7 0.0 0.0 0.0 96.6 0.0 0.1 0.6 0.0 0.0 14.1 0.0 0.3 2.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 1.9 0.0 16.2 0.1 3.2 0.4 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.0 0.0 0.1 28.6 9.1 0.0 0.0 0.0 0.0 41.9 0.6 0.1 0.0 5.6 0.0 5.0 0.0 29.1 9.3 0.1 0.0 1.9 0.0 1.7 0.0 0.0 0.7 23.3 0.0 1.1 0.5 1.2 2.9 0.0 0.0 0.0 0.3 1.9 0.0 0.1 NUP50 NPAP60L ENSG00000093000 "Nucleoporin 50" Q9UKX7 22 45163925-45188017 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047162, HPA048328" Enhanced Enhanced "Nucleoplasm,Nuclear membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "HPA047162: AB_2679963, HPA048328: AB_2680360" "unprognostic (2.64e-1)" "unprognostic (1.21e-2)" "unprognostic (4.96e-2)" "unprognostic (1.22e-1)" "unprognostic (2.17e-1)" "unprognostic (1.57e-1)" "unprognostic (5.46e-3)" "unprognostic (5.83e-3)" "unprognostic (4.94e-2)" "unprognostic (4.94e-2)" "unprognostic (7.22e-2)" "unprognostic (5.31e-2)" "unprognostic (1.97e-2)" "prognostic favorable (4.06e-4)" "unprognostic (1.43e-1)" "unprognostic (3.17e-2)" "unprognostic (3.63e-2)" 14.1 14.8 8.6 23.3 9.9 54.4 13.5 11.9 12.1 14.3 11.2 18.7 16.6 10.1 18.7 20.5 18.1 14.3 7.2 10.7 10.2 13.7 23.5 14.6 33.7 8.1 8.3 13.9 15.9 15.8 6.7 15.5 7.8 12.2 16.7 10.9 11.7 13.4 7.8 19.0 16.3 11.4 8.0 25.5 24.2 29.8 9.2 46.6 15.2 12.7 35.3 19.3 12.3 9.7 75.8 35.5 67.1 43.7 31.0 31.8 70.9 61.9 41.1 46.9 47.1 77.6 32.9 82.7 28.1 41.0 35.1 52.0 83.4 50.5 67.3 44.3 87.4 72.6 54.8 47.7 32.2 193.7 73.7 38.8 34.1 60.1 45.2 22.7 52.4 71.4 76.5 84.3 49.0 50.8 88.2 50.5 50.4 50.0 36.3 91.8 40.7 58.0 37.0 72.5 41.7 40.4 61.5 37.9 74.0 50.9 23.6 50.3 48.3 99.1 88.6 51.6 52.7 58.4 51.3 119.0 37.1 49.2 70.4 55.1 39.1 80.5 20.3 40.2 27.8 19.5 24.5 23.5 25.5 18.1 28.4 19.6 92.7 30.6 24.2 13.9 25.8 34.2 8.6 9.9 11.9 12.1 10.7 10.2 8.1 8.3 7.8 8.0 9.2 9.7 42.7 9.6 27.9 6.2 32.7 85.5 51.9 26.4 48.3 14.6 26.2 16.3 10.8 22.8 29.6 33.1 12.5 22.6 47.5 34.2 13.7 18.9 46.3 56.3 34.7 29.7 17.4 72.4 16.4 20.9 39.8 21.8 59.1 47.3 34.7 23.9 33.2 38.5 28.1 13.5 15.3 24.4 20.3 47.5 32.8 83.3 14.6 33.4 24.9 11.2 56.9 11.1 42.2 11.6 12.5 29.8 33.5 13.9 49.0 60.8 16.9 22.8 50.0 16.3 26.3 15.9 17.1 45.9 44.3 60.6 89.4 56.6 47.1 23.5 26.3 95.3 KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 211.9" "Cell type enhanced" "Detected in many" "Astrocytes: 132.2;Excitatory neurons: 139.6;Oligodendrocytes: 152.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.3;plasmacytoid DC: 10.0" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.3" "Cell line enhanced" "Detected in many" "THP-1: 327.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: AB_10675627" "unprognostic (4.16e-2)" "unprognostic (1.27e-2)" "unprognostic (1.99e-1)" "prognostic favorable (9.22e-5)" "unprognostic (3.16e-2)" "unprognostic (2.44e-1)" "prognostic unfavorable (6.90e-8)" "unprognostic (2.80e-1)" "unprognostic (2.03e-1)" "unprognostic (3.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (8.95e-7)" "unprognostic (6.89e-3)" "unprognostic (5.32e-2)" "unprognostic (5.58e-2)" "unprognostic (1.15e-1)" 33.9 58.3 195.7 27.7 209.3 24.7 25.9 163.3 211.9 46.0 130.3 29.4 14.6 24.0 40.4 34.5 18.2 16.0 18.1 184.1 189.1 23.8 48.4 24.8 29.0 182.8 192.6 13.6 20.1 18.5 19.2 12.0 179.8 29.1 11.2 3.5 26.7 24.7 33.8 64.0 21.4 15.2 170.4 38.7 18.6 26.2 193.6 20.4 18.4 13.1 22.3 44.0 35.6 210.3 49.6 31.5 19.1 38.3 64.1 30.2 19.2 26.9 26.8 28.2 24.1 29.5 26.5 33.2 39.2 42.8 22.5 54.5 29.5 118.6 10.7 35.6 46.4 0.1 42.0 34.3 25.7 89.4 19.7 17.1 59.2 27.3 45.3 21.5 26.8 23.9 11.7 53.1 17.4 56.9 40.0 82.8 18.9 35.8 26.5 48.1 12.9 110.7 42.6 29.7 15.9 28.4 42.5 57.6 75.5 36.8 28.1 327.8 36.5 29.0 50.6 39.7 15.7 44.9 32.9 32.1 34.0 133.7 30.3 0.8 11.0 8.6 2.3 13.9 1.6 2.3 0.9 2.6 12.1 1.8 0.9 1.6 2.5 1.9 17.3 10.0 2.0 3.7 195.7 209.3 163.3 211.9 184.1 189.1 182.8 192.6 179.8 170.4 193.6 210.3 11.4 6.4 8.8 132.2 9.9 52.8 18.6 22.7 6.8 7.3 13.9 13.5 11.5 12.8 11.8 18.4 6.2 2.0 24.9 16.2 0.0 18.6 2.9 11.6 9.3 9.7 10.7 23.1 139.6 20.7 6.5 32.7 4.6 19.5 2.5 3.8 17.5 23.3 67.5 5.0 56.7 10.0 14.2 71.1 50.0 10.8 10.8 59.8 44.4 24.4 68.5 6.5 13.4 16.1 152.9 18.0 13.7 14.7 11.2 25.6 15.7 13.8 9.3 5.9 0.0 10.2 10.9 7.5 4.4 15.2 57.3 2.7 9.3 5.3 12.8 23.1 UPK3A UPK3 ENSG00000100373 "Uroplakin 3A" O75631 22 45284949-45295874 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "prostate: 21.3;skeletal muscle: 35.0;urinary bladder: 48.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 15.0;monocytes: 22.6;Prostatic glandular cells: 54.1;Proximal enterocytes: 29.8;Urothelial cells: 24.5" "Group enriched" "Detected in many" 6 "prostate cancer: 35.3;urothelial cancer: 78.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "myeloid DC: 86.6" "Group enriched" "Detected in many" 16 "dendritic cells: 86.6;monocytes: 32.0" "Group enriched" "Detected in some" 5 "Hep G2: 29.9;RT4: 48.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018407, HPA018415" Enhanced Uncertain "Nuclear membrane,Nuclear bodies" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Nuclear membrane" "Nuclear bodies" "HPA018407: AB_1858641, HPA018415: AB_1858640" "unprognostic (1.27e-2)" "unprognostic (3.20e-3)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "unprognostic (9.42e-2)" "unprognostic (3.98e-5)" "unprognostic (1.69e-2)" "unprognostic (4.82e-4)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-5)" "unprognostic (2.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.83e-1)" "unprognostic (6.05e-3)" 0.2 0.1 0.1 0.5 0.1 1.5 0.2 0.1 0.4 0.0 0.3 1.0 0.0 0.1 0.1 0.3 0.3 0.9 0.1 0.1 0.2 0.1 0.0 0.2 0.9 0.2 0.1 0.1 0.2 4.9 0.7 0.0 0.2 21.3 0.7 0.0 2.8 0.2 35.0 0.0 1.3 0.1 0.1 1.1 0.1 0.1 0.1 0.7 2.3 4.5 0.8 48.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.5 0.0 4.6 0.0 0.1 0.0 0.2 0.0 48.9 0.1 0.0 0.2 0.8 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.0 0.0 0.0 21.2 0.0 0.0 25.8 0.0 1.2 0.0 0.1 86.6 0.5 0.0 0.0 3.6 0.4 32.0 32.9 0.0 7.4 0.1 0.1 0.1 0.4 0.1 0.2 0.2 0.1 0.2 0.1 0.1 0.3 0.2 0.0 0.0 0.7 1.2 0.1 15.0 0.1 0.0 0.1 4.6 3.6 0.2 2.8 0.1 0.0 0.0 0.0 4.0 3.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.1 3.5 0.0 4.8 8.7 1.7 0.3 6.4 0.0 0.0 22.6 0.8 2.1 0.0 0.0 0.0 9.3 0.0 0.1 54.1 29.8 0.0 0.1 0.0 0.0 1.6 0.5 0.0 0.4 0.0 0.4 0.1 0.2 0.0 4.4 24.5 FAM118A "bK268H5.C22.4, C22orf8, FLJ20635" ENSG00000100376 "Family with sequence similarity 118 member A" Q9NWS6 22 45308968-45341955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 104.0;Early spermatids: 125.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003902 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 21: OE19 - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Intermediate filaments" Cytosol "HPA003902: AB_1848368" "unprognostic (6.22e-3)" "unprognostic (1.19e-2)" "unprognostic (9.92e-2)" "unprognostic (1.56e-3)" "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (3.72e-2)" "unprognostic (7.61e-3)" "unprognostic (9.42e-2)" "unprognostic (6.11e-2)" "unprognostic (5.02e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (1.87e-6)" "unprognostic (9.76e-2)" "unprognostic (1.28e-1)" "unprognostic (4.50e-1)" "unprognostic (1.16e-3)" 14.1 11.8 14.9 23.7 16.9 21.5 23.3 22.0 17.1 21.9 25.5 23.3 19.9 17.7 66.5 18.6 12.2 24.4 24.5 17.2 15.6 22.9 17.1 19.3 49.1 14.4 15.3 21.7 14.3 38.3 37.6 18.3 14.4 41.7 12.4 9.5 18.4 9.3 30.5 39.7 24.8 10.3 11.4 25.9 21.3 22.7 17.9 13.6 23.7 6.5 27.6 29.7 22.8 15.8 10.9 7.8 11.0 11.9 9.3 8.9 24.0 8.1 13.4 11.5 11.2 25.6 10.1 48.6 6.5 7.5 6.5 40.7 14.3 10.3 11.5 10.6 31.9 26.3 13.2 18.7 12.8 24.8 7.2 9.5 12.3 17.6 10.8 8.0 7.1 14.6 39.5 52.6 5.9 26.1 14.7 51.3 8.2 49.8 10.4 19.0 7.1 17.4 6.6 28.9 21.8 25.6 8.9 19.0 23.9 18.0 8.2 14.4 9.2 8.8 28.8 10.8 10.8 29.0 5.5 24.7 11.9 17.1 16.0 7.1 7.1 2.2 5.8 6.2 4.7 4.3 7.3 7.2 8.8 6.5 11.5 8.6 5.8 5.6 5.0 13.5 10.9 4.4 14.9 16.9 22.0 17.1 17.2 15.6 14.4 15.3 14.4 11.4 17.9 15.8 12.5 9.6 17.0 23.8 21.2 22.6 36.9 18.8 10.8 18.3 10.9 6.6 11.3 8.6 16.6 7.3 18.8 104.0 83.1 21.4 0.0 7.0 125.0 6.7 15.5 20.7 32.9 14.5 23.1 6.2 8.5 19.2 10.2 7.4 1.3 8.8 23.9 14.5 12.9 6.7 18.3 20.5 12.2 13.0 29.9 75.6 35.8 19.8 1.8 62.8 69.5 16.4 39.1 22.6 21.5 4.8 17.7 23.7 25.8 22.6 13.4 3.9 14.6 22.3 0.0 33.6 14.7 72.5 38.8 8.8 9.9 120.9 55.2 7.3 17.5 35.4 SMC1B "bK268H5, SMC1L2" ENSG00000077935 "Structural maintenance of chromosomes 1B" Q8NDV3 22 45344063-45413619 "Predicted intracellular proteins" "Cell cycle, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 98 "testis: 31.1" "Group enriched" "Detected in some" 6 "Spermatocytes: 897.6;Spermatogonia: 448.5" "Cancer enriched" "Detected in many" 6 "cervical cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.9;EFO-21: 4.0;SiHa: 18.0;U-266/70: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA001500 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA001500: AB_1080030" "unprognostic (1.18e-2)" "unprognostic (6.16e-3)" "unprognostic (2.22e-1)" "unprognostic (3.38e-3)" "unprognostic (1.77e-1)" "unprognostic (3.21e-2)" "unprognostic (6.18e-2)" "unprognostic (1.87e-3)" "unprognostic (3.41e-2)" "unprognostic (3.65e-1)" "unprognostic (4.49e-2)" "unprognostic (3.79e-1)" "unprognostic (3.83e-9)" "unprognostic (2.10e-1)" "unprognostic (1.11e-2)" "unprognostic (1.78e-1)" "unprognostic (1.98e-3)" 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 31.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.2 0.1 0.0 18.0 0.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.4 0.0 3.9 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.0 0.2 0.1 0.0 0.0 0.3 0.6 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 75.6 0.5 0.2 0.8 0.0 0.0 1.4 0.0 0.9 0.3 0.0 0.2 0.0 0.7 0.4 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 36.9 5.6 0.5 0.0 1.0 0.0 0.3 0.0 1.0 1.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.2 1.0 98.6 0.4 0.2 897.6 448.5 0.0 0.0 0.8 0.1 0.0 0.0 0.2 RIBC2 "C22orf11, DKFZp566F0546, FLJ25720" ENSG00000128408 "RIB43A domain with coiled-coils 2" Q9H4K1 22 45413693-45432509 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 14.4;fallopian tube: 9.8;testis: 30.7" "Cell type enhanced" "Detected in some" "Early spermatids: 218.6;Endometrial ciliated cells: 77.5;Late spermatids: 40.4;Respiratory ciliated cells: 101.4;Spermatocytes: 159.4" "Cancer enhanced" "Detected in many" "cervical cancer: 8.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 7.6;CAPAN-2: 7.7;MCF7: 9.2;SiHa: 13.0" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 14.9" HPA003210 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "HPA003210: AB_1078347" "unprognostic (2.55e-1)" "prognostic favorable (7.08e-8)" "unprognostic (3.58e-1)" "unprognostic (1.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (1.30e-3)" "unprognostic (9.51e-3)" "unprognostic (7.21e-3)" "unprognostic (7.34e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (9.95e-5)" "unprognostic (1.41e-1)" "unprognostic (5.32e-2)" "unprognostic (7.91e-2)" "unprognostic (1.13e-1)" 0.0 0.1 0.9 0.6 0.9 1.9 0.2 0.3 0.3 0.9 14.4 0.5 0.3 0.6 0.4 0.7 9.8 0.4 0.0 0.6 0.5 0.1 0.0 0.8 0.4 2.5 2.6 0.2 0.2 1.2 1.4 0.3 1.7 0.6 0.3 0.2 0.2 0.1 0.0 0.9 0.5 0.2 1.6 0.1 0.5 30.7 0.8 0.5 0.5 0.0 0.4 0.1 0.5 2.2 5.9 4.0 0.6 0.0 0.0 0.0 0.5 7.6 0.6 1.5 2.1 4.2 7.7 0.0 1.8 0.7 0.0 6.8 0.0 0.0 1.1 0.0 0.2 0.0 5.7 0.2 0.0 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.8 0.9 0.0 0.0 0.5 9.2 4.0 2.0 0.9 0.1 2.2 4.5 0.0 0.0 2.1 0.8 3.9 0.0 13.0 2.6 0.0 0.4 4.8 2.8 0.4 0.0 0.0 4.6 0.0 2.2 2.3 0.0 0.0 1.2 3.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.9 0.3 0.3 0.6 0.5 2.5 2.6 1.7 1.6 0.8 2.2 0.2 0.0 0.0 0.0 0.1 0.3 0.8 3.6 0.0 0.0 0.6 0.8 0.2 1.5 7.7 0.0 0.0 1.5 0.4 0.8 1.9 0.1 218.6 77.5 1.8 0.3 0.0 4.0 0.9 0.0 0.6 0.9 0.5 2.5 0.0 0.6 0.0 0.0 1.1 0.0 0.3 1.8 12.2 0.0 0.4 40.4 1.2 0.7 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.4 0.1 0.0 101.4 3.6 0.0 0.0 1.9 159.4 22.2 1.2 0.1 0.3 0.4 0.1 1.1 0.3 FBLN1 FBLN ENSG00000077942 "Fibulin 1" P23142 22 45502238-45601135 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 666.3;Endometrial stromal cells: 628.2;Extravillous trophoblasts: 651.6;Fibroblasts: 1506.5;Syncytiotrophoblasts: 1215.9" "Cancer enhanced" "Detected in all" "endometrial cancer: 199.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 1839.4;ASC TERT1: 809.8;BJ: 1029.3;BJ hTERT+: 1615.9;HSkMC: 1345.8;RT4: 1485.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001612, HPA001613, CAB004393, CAB068187" Enhanced Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" NA NA 21000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" "CAB004393: AB_671972, CAB068187: AB_2665634, HPA001612: AB_1078825, HPA001613: AB_1078824" "unprognostic (6.62e-2)" "unprognostic (2.47e-2)" "unprognostic (1.64e-1)" "prognostic favorable (9.28e-4)" "unprognostic (1.26e-3)" "unprognostic (4.82e-2)" "unprognostic (9.79e-3)" "unprognostic (2.49e-1)" "unprognostic (6.30e-2)" "unprognostic (3.86e-2)" "unprognostic (2.84e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.02e-10)" "unprognostic (1.08e-3)" "unprognostic (1.46e-1)" "unprognostic (1.29e-2)" "unprognostic (3.64e-2)" 359.3 123.1 17.3 72.3 29.5 1.7 318.2 27.8 27.5 1131.0 802.4 200.7 75.5 410.6 126.0 305.8 497.6 676.1 773.7 47.0 11.9 61.3 15.7 414.9 16.1 21.8 24.5 214.1 106.3 216.9 90.3 505.7 23.1 466.8 83.6 3.1 121.2 158.5 36.0 296.3 174.5 180.3 15.9 24.9 269.1 21.9 24.7 20.5 195.3 47.5 13.0 704.6 940.5 14.6 17.7 41.6 122.9 258.0 1839.4 809.8 559.8 1029.3 1615.9 89.8 33.8 179.2 5.2 0.4 42.8 38.6 2.5 90.9 78.0 2.7 10.8 0.9 21.0 0.4 209.4 121.5 243.2 1.0 1.0 1345.8 15.8 89.6 32.7 1.8 0.2 1.4 0.9 2.1 63.3 2.4 0.8 3.2 173.8 3.7 15.4 1.4 0.9 2.1 41.1 1485.2 8.7 162.7 127.5 589.6 0.6 344.3 3.7 5.4 8.0 17.4 109.3 465.8 1.0 1.6 0.8 1.4 1.2 1.0 43.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.1 0.2 0.0 2.4 1.2 0.0 0.1 17.3 29.5 27.8 27.5 47.0 11.9 21.8 24.5 23.1 15.9 24.7 14.6 34.4 6.4 1.3 34.3 1.2 170.9 113.4 54.8 21.1 0.1 5.3 11.6 20.1 10.0 28.3 1.8 0.0 666.3 1.6 0.1 0.0 1.3 10.5 61.5 628.2 34.5 0.0 0.0 0.5 0.2 651.6 1506.5 38.7 256.5 1.3 29.0 22.1 0.6 82.4 0.0 0.8 0.3 6.1 0.0 222.9 25.4 92.2 11.4 170.7 41.2 0.0 0.1 0.0 0.0 0.4 1.0 0.1 30.5 4.5 47.4 0.0 0.3 10.2 0.6 118.3 37.1 81.5 42.2 68.7 23.8 130.3 1215.9 18.2 2.3 0.4 86.9 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 WNT7B ENSG00000188064 "Wnt family member 7B" P56706 22 45920366-45977162 "Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.4;skin 1: 17.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.6;Basal prostatic cells: 26.4;Basal squamous epithelial cells: 42.1;Club cells: 23.9;Pancreatic endocrine cells: 43.3;Prostatic glandular cells: 26.2;Urothelial cells: 46.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 119.4;HeLa: 103.7;RPTEC TERT1: 41.4;SK-BR-3: 51.0;U-87 MG: 93.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.02e-3)" "unprognostic (7.83e-3)" "unprognostic (8.51e-2)" "unprognostic (2.93e-2)" "unprognostic (3.26e-2)" "unprognostic (1.31e-1)" "unprognostic (1.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.05e-2)" "unprognostic (3.85e-3)" "unprognostic (1.69e-2)" "unprognostic (8.58e-4)" "unprognostic (1.90e-1)" "unprognostic (6.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.22e-2)" 0.0 0.0 4.6 0.0 3.4 0.0 1.1 1.8 5.1 3.5 0.4 0.0 0.0 0.1 0.1 12.4 1.2 2.9 0.0 4.9 4.5 6.3 0.1 3.1 0.0 2.7 2.3 0.0 0.5 0.1 0.5 0.4 4.3 4.4 0.0 0.0 2.2 1.9 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.3 5.4 0.7 0.3 0.0 1.0 9.1 8.3 1.9 23.2 119.4 0.3 0.0 0.0 0.0 15.2 0.4 1.3 0.0 0.0 0.5 15.5 0.1 3.7 0.2 1.3 25.8 0.9 15.1 0.0 0.1 1.0 0.0 103.7 0.6 0.0 0.0 0.1 0.0 10.2 0.1 3.0 0.4 0.0 0.0 0.0 0.2 0.0 33.1 0.0 0.0 0.1 9.7 22.4 0.0 0.0 1.3 41.4 33.9 4.3 0.0 10.3 51.0 0.0 0.2 8.5 13.6 0.0 2.1 1.8 0.0 1.0 0.0 0.0 0.0 93.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.6 3.4 1.8 5.1 4.9 4.5 2.7 2.3 4.3 1.7 5.4 1.9 0.3 6.4 15.6 3.9 0.5 33.6 26.4 16.3 42.1 0.5 4.0 0.6 1.6 8.6 23.9 12.9 4.2 3.5 0.1 0.1 0.0 5.9 0.3 1.7 0.4 0.7 0.0 0.0 0.3 0.5 0.3 1.7 0.0 4.3 2.5 0.2 0.4 0.1 0.1 0.0 1.2 0.0 0.0 0.0 3.7 0.2 0.3 0.3 0.0 1.0 1.0 0.2 0.0 7.5 0.1 43.3 0.0 0.4 1.5 26.2 0.0 0.1 13.8 1.1 0.0 0.8 1.9 0.2 1.8 21.0 20.5 0.7 0.5 0.0 0.0 46.6 PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243756 "FDA approved drug targets, Metabolic proteins, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 44.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 99.4;Hepatocytes: 144.5;Proximal enterocytes: 93.2;Rod photoreceptor cells: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 10.3;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 5 "dendritic cells: 3.1;granulocytes: 10.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058901, HPA067049, CAB075701" Supported Enhanced Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "CAB075701: , HPA058901: AB_2683849, HPA067049: AB_2685770" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (1.02e-1)" "unprognostic (4.76e-2)" "unprognostic (3.94e-3)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.94e-2)" "unprognostic (2.95e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" "unprognostic (1.01e-1)" "prognostic favorable (4.39e-9)" "unprognostic (4.84e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" 7.9 6.3 9.6 4.5 12.7 6.6 3.8 9.5 6.9 4.1 23.5 11.8 18.4 3.8 3.6 7.7 4.1 4.4 26.3 7.7 8.8 22.4 33.2 4.0 3.4 11.0 11.2 11.2 8.2 7.4 2.6 4.3 10.0 6.2 9.1 18.2 7.8 5.7 26.2 7.7 18.4 4.3 8.6 4.4 6.1 1.3 11.7 3.7 7.0 44.6 3.9 5.1 4.0 10.5 7.8 1.9 2.4 8.4 13.0 8.3 5.3 6.7 13.2 7.0 7.2 3.8 3.7 2.8 3.3 15.6 6.5 3.5 7.1 8.7 6.3 8.1 8.9 8.7 4.8 8.0 8.1 6.0 14.3 6.6 6.9 5.2 11.8 6.0 1.5 6.3 3.2 6.4 6.6 2.0 6.8 2.2 0.3 6.5 1.9 8.0 8.6 3.6 4.7 4.6 2.4 7.0 2.6 2.4 8.0 3.2 2.7 4.6 2.6 7.3 7.7 6.7 2.9 6.3 4.0 1.2 11.4 6.6 2.3 1.4 0.8 10.3 1.0 1.0 0.8 0.8 0.5 0.5 0.6 1.0 0.6 0.4 0.7 0.7 0.7 3.1 1.4 0.2 9.6 12.7 9.5 6.9 7.7 8.8 11.0 11.2 10.0 8.6 11.7 10.5 15.0 3.2 13.6 49.6 8.0 23.3 15.0 7.8 9.1 15.0 14.3 11.4 99.4 22.8 8.9 7.3 62.6 8.0 18.4 58.8 9.8 10.3 0.6 9.4 26.4 15.5 19.9 32.0 1.4 16.6 6.7 16.0 14.8 18.4 5.1 19.1 22.5 144.5 8.8 5.0 13.8 31.4 0.0 24.8 10.2 1.1 19.6 10.4 3.6 10.3 12.2 16.0 8.2 19.6 27.2 13.0 24.5 30.1 10.6 19.1 93.2 40.8 5.0 148.0 6.6 31.0 15.8 0.7 1.7 19.3 34.2 3.0 9.6 14.6 37.9 19.9 CDPF1 "C22orf40, LOC150383" ENSG00000205643 "Cysteine rich DPF motif domain containing 1" Q6NVV7 22 46244011-46250311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018823 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Nucleoplasm "HPA018823: AB_1853018" "unprognostic (1.98e-2)" "unprognostic (5.06e-3)" "unprognostic (1.42e-2)" "prognostic favorable (3.13e-5)" "unprognostic (2.20e-1)" "unprognostic (1.51e-1)" "unprognostic (1.85e-3)" "unprognostic (1.83e-3)" "unprognostic (2.09e-1)" "unprognostic (2.56e-3)" "unprognostic (4.69e-3)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" 6.2 9.5 7.1 4.1 7.3 2.6 6.1 6.9 8.6 8.1 6.7 10.3 4.2 7.8 2.9 4.9 7.2 4.0 8.6 6.9 6.8 7.9 7.5 4.6 6.3 7.6 7.1 7.7 6.7 6.2 6.4 3.8 7.0 8.9 2.8 2.6 6.7 5.1 7.9 5.0 6.3 4.8 6.7 9.1 6.7 3.2 7.1 7.4 8.0 5.8 4.0 7.7 5.7 7.4 5.5 7.2 6.5 9.8 4.7 6.9 6.7 3.3 4.5 6.6 6.3 1.8 7.0 5.1 4.0 2.7 5.3 7.7 3.8 2.8 3.9 7.3 10.3 3.1 5.2 6.3 7.0 9.3 4.3 7.4 7.8 5.8 7.4 7.5 5.8 13.0 5.2 6.9 6.2 3.8 12.1 5.8 5.2 8.0 6.7 8.9 4.3 11.7 5.8 2.1 3.1 7.8 4.2 7.8 9.4 3.8 8.9 5.1 3.7 10.7 7.4 5.9 4.7 7.9 4.0 5.9 5.8 6.3 11.1 1.4 6.4 10.5 10.4 9.1 9.9 6.9 10.0 9.0 6.3 8.3 11.3 8.5 1.6 10.0 9.9 10.9 8.7 8.0 7.1 7.3 6.9 8.6 6.9 6.8 7.6 7.1 7.0 6.7 7.1 7.4 6.9 6.4 3.9 1.0 7.1 1.8 2.9 8.1 1.2 4.5 4.7 6.7 6.1 5.7 4.0 7.3 0.0 12.8 4.5 1.3 7.9 10.7 1.0 2.5 3.3 8.9 4.2 3.4 1.1 11.2 10.0 5.8 3.1 1.9 14.5 6.9 6.8 4.8 9.3 0.0 1.8 3.7 6.1 5.0 2.0 1.2 5.0 4.2 5.4 0.0 8.1 5.7 19.6 1.5 2.5 8.3 1.4 7.9 3.8 5.1 3.4 8.1 6.9 5.4 13.1 4.5 6.5 4.3 8.1 3.1 2.0 4.5 6.1 9.1 5.3 2.1 PKDREJ ENSG00000130943 "Polycystin family receptor for egg jelly" Q9NTG1 22 46255663-46263343 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.4" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Cone photoreceptor cells: 4.2;Early spermatids: 2.5;Horizontal cells: 1.7;Late spermatids: 2.4;Spermatocytes: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA034587 Enhanced NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA034587: AB_10670570" "unprognostic (9.48e-3)" "unprognostic (1.09e-1)" "unprognostic (3.51e-2)" "unprognostic (1.25e-1)" "unprognostic (6.11e-2)" "unprognostic (5.06e-4)" "unprognostic (1.13e-1)" "unprognostic (2.99e-1)" "unprognostic (8.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.17e-3)" "unprognostic (3.41e-1)" "unprognostic (3.36e-2)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.34e-1)" "unprognostic (1.37e-1)" 0.1 0.1 0.1 0.0 0.4 0.1 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.6 0.2 0.0 0.1 0.0 0.1 3.4 0.3 0.0 0.1 0.0 0.0 0.1 0.1 0.5 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 1.8 4.2 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.4 0.0 0.0 0.0 2.4 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 8.4 0.8 0.3 0.6 0.0 0.0 0.0 0.3 0.0 TTC38 FLJ20699 ENSG00000075234 "Tetratricopeptide repeat domain 38" Q5R3I4 22 46267961-46294008 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 233.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 134.2;NK-cells: 182.3;Proximal enterocytes: 144.5;Proximal tubular cells: 149.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 90.5" "Group enriched" "Detected in all" 4 "granulocytes: 29.9;NK-cells: 38.0;T-cells: 90.5" "Cell line enhanced" "Detected in many" "Hep G2: 76.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029302, HPA075893" Approved Approved Cytosol NA NA 170000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "HPA029302: AB_10601704, HPA075893: " "unprognostic (7.78e-2)" "unprognostic (5.85e-2)" "unprognostic (4.92e-3)" "prognostic favorable (3.21e-6)" "unprognostic (8.34e-2)" "unprognostic (6.38e-2)" "unprognostic (8.72e-2)" "unprognostic (3.62e-2)" "unprognostic (9.45e-2)" "unprognostic (7.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.66e-2)" "unprognostic (7.34e-3)" "unprognostic (9.02e-2)" "unprognostic (4.12e-1)" "unprognostic (4.97e-1)" "unprognostic (8.33e-2)" 24.7 23.6 9.5 10.2 11.6 46.9 25.7 10.3 10.7 16.8 12.8 42.1 79.4 13.8 6.4 12.5 17.2 15.5 23.2 9.7 11.0 64.4 233.6 15.6 10.7 13.3 12.3 26.0 35.5 7.6 13.2 7.8 11.9 23.6 31.9 4.7 27.0 7.3 20.6 12.2 80.9 10.3 10.3 22.8 29.1 6.8 12.2 2.5 15.2 12.3 5.9 16.9 13.5 11.3 12.0 13.2 16.4 34.5 15.2 13.1 15.7 17.2 11.5 18.7 14.6 21.8 8.5 0.1 10.8 17.9 7.4 10.8 16.8 13.9 6.8 27.0 36.9 15.6 28.4 76.0 21.0 9.0 59.8 22.6 7.3 8.5 9.7 12.9 15.9 0.2 11.9 19.4 12.2 12.1 0.3 28.2 12.5 22.6 13.1 0.0 8.0 8.0 12.6 13.8 2.9 22.8 23.7 16.3 13.3 7.5 26.1 18.0 18.5 13.0 14.1 10.3 11.0 14.7 9.2 1.7 8.8 13.7 13.8 29.9 11.9 22.5 90.5 11.4 9.7 2.3 8.5 41.0 10.8 1.7 3.5 36.9 7.6 38.0 8.7 4.3 4.5 42.5 9.5 11.6 10.3 10.7 9.7 11.0 13.3 12.3 11.9 10.3 12.2 11.3 9.2 0.0 7.5 13.7 6.5 3.3 5.9 4.3 3.4 2.6 10.2 6.7 9.2 38.6 4.3 9.2 6.2 10.4 69.1 69.0 23.5 10.4 0.3 7.4 9.6 8.9 20.9 10.5 0.3 10.2 9.3 7.5 11.7 6.9 17.2 13.3 9.7 134.2 13.4 5.0 1.8 37.8 4.1 14.9 4.3 0.9 7.5 9.6 5.4 9.4 12.8 9.3 182.3 5.5 5.6 9.7 51.6 13.9 16.2 8.6 144.5 149.6 5.3 5.4 6.6 7.4 5.9 1.8 3.7 5.3 8.2 6.4 29.2 22.7 51.7 4.6 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA000824: AB_2732393, HPA035273: AB_10602901, HPA043300: AB_2678415" "unprognostic (2.96e-1)" "unprognostic (1.09e-2)" "unprognostic (8.07e-2)" "unprognostic (4.27e-2)" "unprognostic (2.64e-1)" "unprognostic (3.52e-3)" "prognostic unfavorable (3.04e-5)" "unprognostic (4.72e-2)" "unprognostic (7.14e-2)" "unprognostic (7.89e-2)" "prognostic favorable (6.86e-4)" "unprognostic (4.74e-3)" "prognostic unfavorable (5.63e-6)" "unprognostic (7.26e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (7.44e-3)" 4.2 7.5 7.7 2.3 7.8 2.9 4.0 8.3 9.6 4.3 8.3 4.5 4.7 3.6 7.5 5.6 3.4 2.6 11.2 7.6 8.5 9.1 8.8 3.5 5.0 8.5 8.6 4.0 10.2 8.0 5.3 4.1 8.5 4.4 4.1 2.8 5.5 4.7 6.9 4.8 4.0 3.9 7.9 4.2 4.3 2.3 8.5 3.0 4.6 8.4 4.3 4.2 4.1 7.8 17.8 16.0 6.6 15.1 12.2 8.6 16.6 18.1 12.6 24.9 19.2 22.7 4.5 11.5 12.5 16.2 10.9 15.3 28.5 16.0 21.1 7.5 38.4 13.6 25.0 27.1 10.4 26.5 9.0 8.2 17.6 25.8 8.1 10.3 16.2 5.8 19.3 2.7 15.3 19.1 10.4 21.5 25.5 10.6 27.5 12.2 14.4 21.2 12.5 12.1 15.9 19.0 16.0 18.5 31.7 8.2 10.7 10.9 11.9 11.1 19.8 15.8 20.7 6.5 7.8 12.6 15.7 19.1 22.8 0.0 6.2 3.8 9.4 9.0 8.3 5.4 8.2 8.9 7.1 5.5 7.3 6.9 1.3 8.0 9.8 5.8 11.0 5.9 7.7 7.8 8.3 9.6 7.6 8.5 8.5 8.6 8.5 7.9 8.5 7.8 12.7 9.6 6.1 22.9 13.2 6.2 10.8 16.8 7.4 26.4 10.6 11.8 14.7 10.0 10.7 11.0 16.7 24.9 16.1 14.1 27.4 20.1 1.6 6.3 10.2 14.5 12.5 14.3 19.4 19.6 21.0 11.9 21.9 6.6 9.5 26.8 13.9 16.8 15.9 13.5 18.0 12.3 10.2 9.9 4.0 3.3 15.2 8.8 8.8 5.6 14.9 11.9 20.6 10.1 14.6 19.5 9.9 17.0 13.8 14.2 15.3 27.9 10.2 26.4 6.6 7.6 14.4 18.5 12.9 9.6 9.7 15.3 13.1 21.0 19.3 9.9 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 GRAMD4 "DIP, KIAA0767" ENSG00000075240 "GRAM domain containing 4" Q6IC98 22 46576012-46679790 "Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.2" "Cell type enhanced" "Detected in many" "Astrocytes: 45.1;Distal enterocytes: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (8.67e-3)" "unprognostic (1.78e-3)" "unprognostic (2.19e-2)" "unprognostic (8.11e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.04e-4)" "unprognostic (1.08e-1)" "unprognostic (7.07e-2)" "unprognostic (5.72e-2)" "unprognostic (1.44e-3)" "unprognostic (1.54e-2)" "unprognostic (4.11e-1)" "unprognostic (1.61e-2)" "unprognostic (2.73e-2)" "unprognostic (2.08e-1)" "unprognostic (5.38e-2)" "unprognostic (8.69e-2)" 15.1 52.1 15.1 17.4 15.9 22.6 11.9 9.3 20.2 11.5 11.9 40.6 34.6 7.5 9.9 24.2 16.1 20.5 45.0 15.6 11.9 18.6 168.2 19.6 17.6 11.6 11.6 10.8 17.6 10.0 24.1 10.5 12.0 14.1 26.6 9.1 17.8 7.1 23.8 45.3 36.0 9.1 11.2 16.0 28.0 7.4 11.8 23.5 20.3 11.9 26.6 9.4 13.2 13.8 12.6 14.2 16.3 20.9 21.4 12.5 16.8 9.5 5.9 3.8 4.8 5.1 19.6 45.9 15.9 10.7 11.1 26.2 10.0 5.2 5.8 12.2 11.3 15.4 10.9 12.2 17.4 96.9 60.0 8.4 12.2 3.0 6.8 13.4 5.3 34.6 29.4 30.3 5.4 22.0 56.4 51.0 8.9 28.2 6.6 25.3 2.5 30.2 7.4 14.6 11.6 32.3 10.2 20.3 37.1 18.7 19.8 33.8 8.3 4.9 9.7 6.6 6.3 6.2 21.5 24.3 10.9 37.4 43.1 1.2 1.4 1.0 0.6 0.9 0.3 1.0 0.5 0.4 2.0 0.3 0.4 0.2 0.5 3.9 0.4 2.4 1.9 0.8 15.1 15.9 9.3 20.2 15.6 11.9 11.6 11.6 12.0 11.2 11.8 13.8 17.7 16.0 18.4 45.1 5.9 8.2 3.6 7.6 6.8 5.0 7.1 10.8 19.3 8.6 4.1 3.7 0.0 3.7 9.5 56.1 0.0 4.7 0.3 13.4 7.2 7.5 20.8 3.8 21.6 6.7 2.2 4.7 8.2 10.6 7.0 5.4 2.5 23.0 14.0 3.3 18.2 20.7 6.1 10.1 14.7 1.1 4.7 12.0 7.2 11.2 10.9 12.2 3.1 13.6 5.9 7.9 18.9 5.7 8.6 5.0 34.5 3.0 5.1 1.7 0.0 3.4 5.3 1.2 3.8 8.2 10.4 3.4 7.0 5.9 22.8 3.7 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" 15.7 23.7 17.5 22.2 18.1 21.1 12.7 33.2 22.5 17.8 16.4 17.9 31.6 17.5 6.0 14.8 18.2 17.4 39.0 18.3 37.4 19.5 18.9 16.6 26.1 32.1 34.5 26.6 30.2 11.5 49.0 10.0 33.2 11.7 14.9 21.1 17.5 13.4 20.8 16.3 31.2 15.2 20.8 19.4 21.9 6.0 26.2 38.7 21.0 19.2 25.2 13.7 12.4 18.4 25.6 15.1 71.6 22.6 40.3 30.2 6.7 43.7 33.8 24.5 17.2 22.3 8.4 35.3 19.9 46.9 15.1 16.3 30.4 19.8 24.9 12.6 33.0 15.8 36.9 29.0 27.9 49.9 4.0 25.3 25.0 26.7 9.1 39.2 73.5 37.1 12.1 44.5 45.4 1.9 34.0 24.8 32.4 10.3 16.3 62.8 81.2 40.4 14.7 0.5 66.4 60.6 21.5 10.3 47.1 16.5 11.3 37.6 67.4 50.2 26.8 37.5 64.4 45.7 59.5 22.3 53.5 28.0 41.7 0.7 3.0 3.7 10.3 7.0 17.9 2.0 10.7 10.0 5.4 2.1 6.3 5.8 4.2 2.6 8.7 5.7 10.4 4.4 17.5 18.1 33.2 22.5 18.3 37.4 32.1 34.5 33.2 20.8 26.2 18.4 28.6 9.6 16.6 16.0 17.0 3.4 6.3 6.1 18.2 24.4 6.1 9.8 44.2 10.0 11.0 1.8 6.2 2.4 25.4 23.4 15.6 12.8 7.8 10.3 19.8 27.4 14.4 8.0 11.7 11.8 1.4 14.1 9.2 19.8 10.1 10.2 25.4 22.1 10.8 26.9 21.9 6.6 8.2 24.8 16.9 16.0 9.6 22.1 3.6 15.9 18.6 25.6 22.6 9.5 4.2 10.9 15.2 15.1 43.3 2.1 50.0 16.8 0.7 9.7 0.0 8.3 13.2 4.7 1.7 11.0 4.4 1.8 37.6 5.3 20.0 1.7 TBC1D22A C22orf4 ENSG00000054611 "TBC1 domain family member 22A" Q8WUA7 22 46762617-47175699 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 252.9;Oligodendrocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001173 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA001173: AB_1080212" "unprognostic (1.62e-1)" "unprognostic (5.90e-3)" "unprognostic (1.10e-1)" "unprognostic (4.79e-3)" "unprognostic (3.65e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (5.95e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.69e-1)" "unprognostic (9.17e-2)" "unprognostic (4.68e-2)" "unprognostic (4.93e-2)" "unprognostic (4.14e-1)" "unprognostic (1.09e-1)" "unprognostic (2.39e-1)" 13.4 12.3 10.5 14.4 9.9 10.4 11.8 9.0 10.5 11.8 7.9 12.5 14.9 10.5 6.8 18.1 12.1 9.3 12.9 10.4 9.2 13.3 11.0 12.7 19.4 11.3 11.5 9.8 14.7 12.0 11.2 12.0 10.7 9.3 9.5 4.9 14.1 7.8 17.9 17.6 15.0 7.6 9.8 19.1 14.8 7.3 11.0 14.7 12.3 11.3 18.4 11.0 12.3 11.4 19.1 13.0 8.1 9.9 11.6 16.1 9.9 12.8 17.2 14.3 15.3 14.8 14.5 16.6 13.9 19.5 8.9 20.7 7.0 20.0 9.9 7.2 19.6 9.5 11.1 28.6 17.7 20.9 7.4 18.9 23.0 9.8 13.6 17.2 23.7 10.4 6.2 17.4 13.1 9.8 9.3 10.7 8.0 17.9 14.6 11.8 9.5 17.9 16.7 9.7 6.6 12.3 11.8 4.5 20.1 10.0 10.5 13.7 19.5 10.9 15.3 11.5 8.2 11.5 3.9 10.5 27.0 10.6 6.9 2.5 10.7 6.3 6.4 15.5 6.0 11.6 5.9 6.1 12.5 13.0 3.9 4.3 15.5 5.5 18.6 6.1 10.2 6.6 10.5 9.9 9.0 10.5 10.4 9.2 11.3 11.5 10.7 9.8 11.0 11.4 20.3 25.6 18.3 81.0 47.0 6.4 12.1 21.1 21.6 18.6 9.9 7.9 8.6 14.3 20.2 7.3 18.8 24.4 22.7 27.9 11.7 25.8 13.9 20.1 14.2 19.0 3.6 13.5 82.0 23.5 19.6 12.2 39.3 14.5 17.1 13.3 23.2 7.9 33.1 21.9 94.2 16.2 18.3 23.0 16.7 3.5 9.9 32.7 10.6 252.9 39.4 13.7 29.9 76.9 113.2 30.2 25.2 11.7 28.8 10.5 39.4 19.8 15.0 27.3 13.1 12.3 11.8 7.9 10.5 18.5 8.0 29.0 22.7 12.7 18.4 11.8 TAFA5 "FAM19A5, TAFA-5" ENSG00000219438 "TAFA chemokine like family member 5" Q7Z5A7 22 48489553-48850912 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 85.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Fibroblasts: 1.1" "Cancer enhanced" "Detected in all" "glioma: 13.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 17.3;HEK 293: 13.6;Hep G2: 32.1;NTERA-2: 12.7;U-2 OS: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025629 Approved "Secreted in brain" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" "CAB025629: " "unprognostic (2.86e-1)" "unprognostic (2.98e-1)" "unprognostic (3.42e-2)" "unprognostic (2.19e-1)" "unprognostic (3.57e-1)" "unprognostic (1.80e-1)" "unprognostic (2.82e-3)" "unprognostic (2.41e-2)" "unprognostic (6.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.26e-1)" "unprognostic (9.31e-3)" "unprognostic (2.64e-2)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.94e-2)" 2.7 1.3 50.3 0.8 40.6 0.0 2.0 37.0 51.8 19.7 15.0 8.4 1.0 8.1 4.7 0.9 5.2 2.0 2.5 53.9 43.0 2.4 2.7 2.1 0.4 55.2 85.9 12.1 2.4 4.3 7.0 0.1 51.1 6.8 0.2 3.6 4.9 3.2 1.5 5.4 3.3 0.7 41.5 0.3 2.9 3.3 49.6 1.2 0.8 1.7 0.1 4.0 4.9 28.2 0.0 1.3 2.5 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 17.3 0.1 0.1 1.3 0.0 0.0 0.0 13.6 0.0 0.2 32.1 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.1 0.3 12.7 0.6 0.0 0.6 0.0 7.4 0.0 0.0 7.2 0.2 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 21.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.3 40.6 37.0 51.8 53.9 43.0 55.2 85.9 51.1 41.5 49.6 28.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BRD1 "BRL, BRPF2" ENSG00000100425 "Bromodomain containing 1" O95696 22 49773283-49827512 "Predicted intracellular proteins" "Erythrocyte maturation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000807, HPA001063" Enhanced Supported "Nuclear speckles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "HPA000807: AB_1078298, HPA001063: AB_1078297" "unprognostic (1.96e-1)" "unprognostic (2.99e-2)" "unprognostic (1.07e-1)" "unprognostic (5.11e-3)" "unprognostic (1.07e-1)" "unprognostic (2.47e-2)" "unprognostic (2.18e-2)" "unprognostic (9.98e-2)" "unprognostic (2.73e-2)" "unprognostic (3.28e-2)" "unprognostic (2.02e-3)" "unprognostic (1.64e-3)" "unprognostic (5.87e-2)" "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-3)" 11.4 7.3 3.1 8.1 3.0 15.0 10.8 12.0 5.0 12.5 3.6 14.7 11.7 15.8 2.8 12.8 13.7 7.7 7.5 3.4 3.2 5.4 6.9 10.0 9.4 3.2 2.8 16.0 13.2 8.5 11.2 8.3 2.9 8.7 5.8 6.1 12.1 8.0 16.7 23.2 12.0 6.7 1.5 12.0 11.5 30.7 3.2 14.0 10.2 8.9 7.6 11.8 12.3 4.5 12.7 12.7 22.8 12.8 9.2 8.2 19.3 13.7 9.3 14.2 11.1 19.3 8.3 13.3 7.9 11.4 5.2 17.9 14.7 9.8 6.1 13.4 26.6 13.2 20.3 11.8 17.8 30.5 18.2 12.2 15.1 8.3 10.5 10.3 10.4 15.9 15.3 14.3 7.3 20.8 23.0 15.9 15.7 9.4 10.1 33.6 19.9 13.9 5.5 18.2 14.6 25.8 17.6 22.7 18.4 10.5 10.6 24.9 12.9 13.1 14.1 9.9 12.7 16.8 4.3 18.9 9.3 10.7 11.8 0.3 0.6 0.7 0.5 0.2 1.0 0.4 0.8 1.0 0.4 0.7 0.8 1.0 0.6 0.8 2.9 0.9 0.3 0.5 3.1 3.0 12.0 5.0 3.4 3.2 3.2 2.8 2.9 1.5 3.2 4.5 25.9 22.4 27.6 16.3 13.8 15.8 5.7 7.1 8.6 26.6 14.0 14.7 8.4 5.7 12.7 3.7 29.2 6.7 76.8 13.3 0.0 6.7 7.5 32.4 37.1 13.9 16.2 8.2 25.3 9.3 6.6 17.2 14.8 47.7 10.1 28.3 14.3 12.3 6.7 33.7 22.2 13.9 4.1 13.3 14.0 6.7 11.8 15.4 12.4 16.9 11.2 13.8 7.2 19.1 21.9 9.5 8.7 13.9 43.1 9.1 10.6 3.2 11.3 36.1 0.0 25.4 20.1 42.6 19.7 10.7 18.5 10.1 40.6 26.4 11.3 9.0 ZBED4 KIAA0637 ENSG00000100426 "Zinc finger BED-type containing 4" O75132 22 49853844-49890080 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045341 Approved Supported Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA045341: AB_2679295" "unprognostic (3.82e-2)" "unprognostic (6.39e-2)" "unprognostic (7.22e-3)" "unprognostic (4.43e-2)" "unprognostic (7.90e-2)" "unprognostic (2.42e-1)" "unprognostic (2.48e-3)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "unprognostic (8.74e-3)" "unprognostic (9.44e-2)" "unprognostic (2.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (2.18e-1)" "unprognostic (2.53e-2)" "unprognostic (5.20e-2)" 3.6 2.6 2.3 5.3 2.1 11.0 3.4 5.6 2.3 3.1 1.3 5.7 5.3 3.5 2.7 6.5 3.3 3.5 3.3 2.2 1.6 3.7 4.7 4.2 6.6 2.2 1.9 3.6 5.3 3.0 3.3 3.9 2.1 3.4 4.8 4.7 3.8 2.1 4.5 5.0 5.3 3.2 1.2 5.1 4.5 3.8 2.2 10.9 3.3 3.2 5.5 4.0 3.5 4.0 14.9 13.1 24.5 19.5 7.4 8.1 15.2 8.6 7.1 9.3 8.6 13.5 6.5 29.3 5.9 9.2 9.7 16.7 17.4 11.1 9.9 11.6 21.2 16.8 13.2 12.8 10.7 36.0 23.2 7.6 16.5 10.2 15.4 9.3 12.6 28.0 18.2 13.7 11.1 11.9 30.0 17.1 13.4 12.9 9.1 35.5 22.1 17.8 9.9 14.9 12.9 25.7 8.5 24.9 17.3 15.2 11.8 20.3 14.7 12.7 19.9 7.5 12.3 13.5 9.0 26.5 7.7 15.9 15.2 0.4 0.4 0.7 0.8 0.6 1.6 0.6 0.8 0.9 1.0 0.4 1.0 0.8 0.2 2.9 0.6 1.0 0.6 0.6 2.3 2.1 5.6 2.3 2.2 1.6 2.2 1.9 2.1 1.2 2.2 4.0 4.9 0.0 6.5 11.4 7.2 5.1 5.1 5.0 4.0 7.9 6.3 6.1 7.2 7.2 8.6 5.5 14.6 3.6 23.5 8.7 3.9 9.2 4.8 10.0 10.1 6.6 12.6 12.8 14.7 7.1 6.4 5.1 7.7 10.1 0.0 10.1 5.3 6.9 6.8 13.5 14.7 9.5 4.1 12.6 5.2 4.6 3.1 7.3 0.0 16.9 8.5 2.5 16.5 12.1 16.6 13.3 8.5 4.1 12.5 9.2 3.8 2.9 6.2 9.9 6.6 5.8 7.1 4.8 6.4 6.7 3.8 3.3 17.2 7.4 11.0 6.8 ALG12 "CDG1G, ECM39" ENSG00000182858 "ALG12 alpha-1,6-mannosyltransferase" Q9BV10 22 49900229-49918438 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003076, HPA051665" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Endoplasmic reticulum" "HPA003076: AB_2666777, HPA051665: AB_2681566" "unprognostic (1.66e-1)" "unprognostic (1.26e-1)" "unprognostic (4.39e-3)" "prognostic favorable (6.09e-4)" "unprognostic (2.29e-1)" "unprognostic (3.32e-2)" "unprognostic (4.27e-3)" "unprognostic (3.33e-2)" "unprognostic (1.46e-1)" "unprognostic (3.32e-2)" "unprognostic (1.42e-1)" "unprognostic (2.21e-1)" "prognostic favorable (3.60e-5)" "unprognostic (1.62e-2)" "unprognostic (3.00e-2)" "unprognostic (9.89e-3)" "unprognostic (6.32e-2)" 6.3 8.0 3.5 7.3 4.5 5.9 6.4 6.2 4.7 7.6 4.9 8.8 11.1 8.3 6.5 8.0 7.6 6.6 8.3 3.9 2.6 10.3 14.5 7.0 5.6 4.5 4.3 7.1 11.4 11.8 6.6 5.4 4.7 9.1 4.1 3.0 12.0 5.6 6.1 7.2 8.9 4.4 3.3 7.2 10.3 4.5 4.9 6.5 11.7 4.5 4.8 7.7 6.8 8.4 8.6 8.5 8.8 14.7 16.4 7.6 9.8 8.8 7.9 10.2 8.2 14.0 12.0 4.6 7.8 7.8 11.1 15.2 10.7 10.4 5.0 7.3 15.9 4.2 14.7 14.1 18.6 10.6 8.9 11.6 10.5 9.9 14.3 11.2 9.9 10.3 5.3 11.2 5.4 19.6 10.4 8.6 8.4 11.3 7.7 17.2 11.0 12.1 10.6 9.6 5.9 9.6 14.0 26.3 11.4 11.7 10.8 9.4 7.7 11.2 8.5 7.9 6.8 9.8 4.9 6.1 12.5 8.0 10.9 21.4 8.7 7.7 11.5 8.5 11.7 4.8 8.9 11.4 7.6 6.4 7.3 8.6 7.1 16.9 10.1 7.7 12.8 8.1 3.5 4.5 6.2 4.7 3.9 2.6 4.5 4.3 4.7 3.3 4.9 8.4 6.8 9.6 3.1 21.5 10.2 4.1 10.2 12.1 9.1 5.2 11.1 10.2 1.2 8.6 10.3 18.4 2.1 20.5 8.5 16.6 3.9 15.9 6.9 6.6 8.0 8.1 6.7 7.4 23.2 13.5 22.4 10.6 11.7 9.2 8.2 7.0 5.3 15.0 18.6 3.3 30.4 12.9 12.2 9.2 5.3 4.3 8.7 8.7 10.6 9.4 9.0 2.9 18.6 17.6 40.4 10.3 9.7 8.2 15.6 11.3 18.8 6.8 5.6 5.2 0.0 8.5 7.7 12.9 9.1 10.4 6.0 26.3 11.9 8.3 16.3 9.1 CRELD2 MGC11256 ENSG00000184164 "Cysteine rich with EGF like domains 2" Q6UXH1 22 49918167-49927540 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 349.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000603, CAB025604" Approved "Intracellular and membrane" NA NA 480000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" "CAB025604: , HPA000603: AB_1078565" "unprognostic (1.12e-1)" "unprognostic (7.35e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.42e-7)" "unprognostic (5.04e-2)" "unprognostic (5.43e-2)" "unprognostic (3.21e-3)" "unprognostic (2.71e-1)" "unprognostic (3.60e-1)" "unprognostic (1.24e-1)" "unprognostic (2.57e-2)" "unprognostic (7.97e-2)" "prognostic unfavorable (1.34e-9)" "unprognostic (6.13e-2)" "unprognostic (3.01e-1)" "unprognostic (7.30e-2)" "unprognostic (4.02e-1)" 29.0 28.5 17.7 25.8 20.6 18.1 24.1 19.3 20.1 25.4 19.2 29.6 26.4 31.5 41.8 26.6 28.2 13.6 33.0 18.3 21.4 26.7 97.8 31.5 19.1 22.1 19.9 23.5 123.3 13.0 65.5 14.4 21.5 27.3 16.4 7.7 39.5 17.1 15.8 17.0 26.8 15.8 19.0 40.3 46.0 43.2 24.9 15.4 67.4 7.6 15.2 27.1 21.3 21.9 37.5 25.5 29.3 96.6 30.6 34.6 39.1 76.4 46.0 41.9 35.5 44.7 44.0 20.4 59.6 66.2 42.3 36.4 37.1 38.3 18.0 11.0 60.1 11.2 37.3 55.8 126.1 44.1 41.4 31.8 33.6 36.4 30.6 29.5 42.9 21.8 16.5 79.5 31.8 119.3 17.2 46.2 21.1 73.9 54.7 41.1 51.9 46.4 20.3 33.6 19.0 53.5 64.9 75.2 32.0 19.3 30.8 51.8 32.7 35.5 59.2 33.1 23.9 65.4 16.9 17.9 52.6 32.5 57.3 33.5 12.4 17.2 17.2 14.9 17.7 29.2 14.9 23.2 13.7 28.1 12.4 10.2 6.4 35.4 8.9 52.2 11.3 12.9 17.7 20.6 19.3 20.1 18.3 21.4 22.1 19.9 21.5 19.0 24.9 21.9 42.4 6.4 16.1 12.7 82.6 32.8 34.4 49.0 10.2 34.7 35.3 34.2 17.7 31.5 39.6 9.2 25.0 32.4 65.6 45.6 7.9 41.2 112.5 28.4 41.5 32.2 39.9 12.4 9.7 63.2 120.5 56.8 50.4 37.0 36.2 27.0 47.2 63.9 74.6 25.2 10.9 136.3 26.4 25.7 47.0 25.8 44.1 33.8 96.0 6.5 27.8 41.7 80.3 9.5 16.2 51.2 35.1 41.3 349.6 82.4 28.2 16.6 37.4 32.0 13.1 25.7 39.7 143.5 104.8 21.6 30.7 55.1 53.0 41.0 55.7 43.8 PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 408.4;Syncytiotrophoblasts: 389.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 163.3;SK-BR-3: 144.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068758 Supported Cytosol NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Cytosol "HPA068758: AB_2686026" "unprognostic (3.67e-2)" "unprognostic (7.69e-3)" "unprognostic (1.07e-1)" "unprognostic (1.11e-1)" "unprognostic (3.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.48e-2)" "unprognostic (1.13e-2)" "unprognostic (2.71e-2)" "prognostic unfavorable (9.68e-4)" "unprognostic (2.00e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.09e-4)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (3.92e-3)" "unprognostic (7.27e-3)" 97.8 48.4 25.9 31.3 31.3 114.3 80.2 32.8 38.1 49.2 26.9 55.1 23.8 40.8 12.7 80.8 54.0 25.8 68.7 25.2 32.6 113.3 92.9 107.1 28.2 40.6 36.1 35.7 73.1 21.6 51.3 21.3 38.0 87.3 10.4 3.1 93.5 22.6 112.0 116.4 51.6 9.9 30.3 80.7 118.1 33.9 35.2 19.0 54.9 35.0 13.0 71.0 68.6 39.9 26.8 17.7 11.6 21.9 9.0 6.7 65.5 16.5 26.7 19.4 14.0 29.5 22.3 47.3 20.1 4.6 39.1 22.5 22.3 12.6 6.9 35.8 92.1 19.5 46.3 36.0 41.8 42.5 36.0 12.8 41.0 11.9 20.2 10.5 63.5 31.7 27.0 163.3 5.9 60.6 21.7 76.4 24.2 28.1 27.8 100.3 19.2 57.6 10.6 20.3 41.1 28.6 32.2 144.7 109.2 10.7 19.0 56.4 16.8 12.1 51.5 19.8 27.1 82.2 56.9 41.4 30.1 24.1 33.2 0.0 4.0 0.1 2.2 4.1 2.5 4.3 5.0 4.4 3.1 7.5 4.8 1.9 20.7 1.7 5.2 7.0 5.8 2.7 25.9 31.3 32.8 38.1 25.2 32.6 40.6 36.1 38.0 30.3 35.2 39.9 120.2 64.1 85.9 6.5 107.7 227.3 236.8 79.1 96.8 31.5 99.2 67.3 32.8 121.5 72.8 80.9 2.1 56.9 79.5 57.9 84.1 50.9 5.1 114.2 76.3 167.7 97.7 10.8 10.2 54.5 346.5 69.0 202.3 170.5 69.3 16.8 98.6 45.9 69.7 62.2 6.7 101.7 81.4 41.1 408.4 4.8 32.3 134.8 108.5 6.5 35.8 14.0 11.3 6.6 20.5 71.0 94.6 11.3 95.1 298.4 58.1 88.5 40.9 16.5 26.3 39.4 57.3 26.1 37.7 95.3 204.7 389.9 90.4 11.6 79.0 266.0 IL17REL FLJ41993 ENSG00000188263 "Interleukin 17 receptor E like" Q6ZVW7 22 49994513-50012659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.3;stomach 1: 2.3" "Cell type enriched" "Detected in single" 21 "Gastric mucus-secreting cells: 12.8" "Cancer enhanced" "Detected in some" "stomach cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA045546 Supported NA NA "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA045546: AB_10963836" "unprognostic (3.33e-1)" "unprognostic (1.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-1)" "unprognostic (6.33e-2)" "unprognostic (4.65e-4)" "unprognostic (2.72e-2)" "unprognostic (1.01e-3)" "unprognostic (4.45e-2)" "unprognostic (1.52e-1)" "unprognostic (3.94e-1)" "unprognostic (3.02e-2)" "unprognostic (4.60e-4)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (6.31e-3)" "unprognostic (8.31e-2)" 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 1.0 2.3 0.1 1.0 3.9 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.6 0.1 0.3 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TTLL8 ENSG00000138892 "Tubulin tyrosine ligase like 8" A6PVC2 22 50015123-50056935 "Predicted intracellular proteins" Ligase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "testis: 4.2" "Group enriched" "Detected in some" 42 "Cardiomyocytes: 1.8;Early spermatids: 4.6;Late spermatids: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA016882 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA016882: AB_10603223" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (8.18e-2)" "unprognostic (1.21e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MLC1 "KIAA0027, LVM, MLC, VL" ENSG00000100427 "Modulator of VRAC current 1" Q15049 22 50059391-50085426 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 262.7;choroid plexus: 145.6" "Cell type enriched" "Detected in some" 6 "Astrocytes: 115.6" "Cancer enriched" "Detected in some" 69 "glioma: 122.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 20.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HL-60: 228.2;NB-4: 219.8;THP-1: 401.5;U-266/70: 131.6;U-266/84: 120.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003040 Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "HPA003040: AB_1079387" "unprognostic (2.68e-2)" "unprognostic (5.46e-6)" "unprognostic (5.41e-3)" "unprognostic (1.51e-1)" "unprognostic (1.47e-1)" "unprognostic (2.42e-3)" "unprognostic (9.54e-3)" "unprognostic (7.21e-2)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-1)" "unprognostic (1.51e-3)" "unprognostic (8.39e-4)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (3.66e-2)" "unprognostic (2.92e-1)" 0.3 0.1 239.3 0.7 235.7 36.4 0.1 212.7 261.8 3.0 145.6 0.1 0.4 0.3 1.0 0.1 1.8 1.0 0.6 225.8 234.5 0.1 0.4 1.6 0.3 262.7 243.1 0.3 0.1 0.0 1.1 2.3 221.8 4.8 0.0 4.1 0.1 1.4 0.1 1.0 0.1 0.2 231.9 2.2 0.2 3.8 231.5 0.5 0.1 0.0 0.5 0.4 11.9 217.2 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 68.1 0.0 0.0 0.1 228.2 68.4 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 1.8 219.8 0.3 0.0 0.1 24.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 401.5 0.0 0.0 0.2 0.1 0.3 131.6 120.2 0.4 0.3 35.7 2.2 0.0 1.1 0.0 3.9 6.8 0.1 0.1 0.3 1.6 0.9 0.0 0.1 1.8 0.1 20.2 9.2 0.2 0.1 4.0 239.3 235.7 212.7 261.8 225.8 234.5 262.7 243.1 221.8 231.9 231.5 217.2 0.0 0.0 0.5 115.6 0.3 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 0.1 17.2 0.0 0.0 0.0 1.1 0.1 0.4 0.1 0.0 7.8 0.4 0.0 0.1 2.4 0.0 0.1 1.3 4.4 0.4 0.0 3.5 0.0 0.5 0.0 0.0 0.3 0.0 0.7 0.0 0.6 1.8 7.5 0.6 16.3 18.6 0.5 0.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.3 2.7 0.1 0.0 0.0 MOV10L1 "CHAMP, DJ402G11.8, DKFZp434B0717" ENSG00000073146 "Mov10 like RISC complex RNA helicase 1" Q9BXT6 22 50089879-50161690 "Enzymes, Predicted intracellular proteins" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 42.6" "Cell type enhanced" "Detected in some" "Early spermatids: 118.9;Late spermatids: 310.8;Spermatocytes: 80.3;Spermatogonia: 46.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.5;HUVEC TERT2: 12.5;TIME: 5.8" "Not detected" "Not detected" HPA019034 Approved NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "HPA019034: AB_1854070" "unprognostic (1.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.88e-2)" "unprognostic (7.91e-2)" "unprognostic (4.29e-2)" "unprognostic (4.05e-2)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (9.43e-2)" "unprognostic (7.51e-2)" "unprognostic (6.26e-2)" "unprognostic (2.03e-1)" "unprognostic (8.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" 0.6 0.1 1.2 0.2 1.1 0.2 0.4 4.0 1.5 3.3 0.0 2.0 0.1 4.4 1.6 0.6 2.1 1.0 0.8 1.1 0.5 0.5 0.8 0.6 0.2 1.2 0.6 3.0 0.2 0.0 1.0 0.6 1.4 2.1 0.2 1.3 0.5 0.1 0.0 0.3 1.1 1.6 0.2 0.0 0.2 42.6 0.7 0.0 0.5 0.0 0.2 0.5 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.4 0.7 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 2.5 0.0 1.1 0.1 0.0 0.0 0.0 0.1 12.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.1 4.0 1.5 1.1 0.5 1.2 0.6 1.4 0.2 0.7 0.6 0.3 0.0 0.0 1.3 0.0 0.3 0.1 0.1 0.0 3.1 0.1 0.3 1.6 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 118.9 0.3 5.2 0.8 0.0 0.0 5.5 0.4 0.1 0.6 0.0 0.5 0.0 0.7 0.4 0.1 1.7 5.0 3.2 0.0 0.0 0.0 0.0 310.8 1.5 0.2 0.0 8.4 0.0 2.3 0.0 1.5 1.1 0.0 0.0 3.0 0.0 0.1 0.0 1.7 0.0 3.7 13.1 0.2 0.3 80.3 46.7 0.1 0.0 0.1 0.1 0.3 0.0 0.1 PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.4;Excitatory neurons: 13.3;Hepatocytes: 10.7;Inhibitory neurons: 15.8;Muller glia cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 10.3;HDLM-2: 16.7;Hep G2: 19.6;MCF7: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA004624: , HPA039117: AB_10805354" "unprognostic (1.00e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-9)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.00e-1)" "unprognostic (4.08e-1)" 1.0 0.8 4.4 0.5 4.4 1.6 1.0 8.4 40.1 1.7 0.0 0.3 0.0 1.2 0.5 5.2 2.2 0.4 0.7 8.0 13.1 3.0 9.6 2.1 0.0 51.0 8.8 3.4 1.4 0.3 7.9 0.1 48.4 3.9 0.0 1.6 5.0 1.4 0.7 1.1 0.2 0.0 7.9 1.9 0.4 1.7 14.1 0.0 7.3 0.1 0.1 1.4 1.9 16.4 0.9 2.1 0.4 2.3 0.0 0.2 4.9 2.6 2.5 0.5 0.4 0.5 8.0 0.0 10.3 0.3 1.4 0.5 1.3 1.0 0.1 16.7 1.4 0.4 3.5 19.6 0.7 0.1 1.2 0.2 1.0 0.7 0.0 1.1 0.6 0.0 1.4 0.0 0.2 10.8 0.0 1.0 3.9 0.0 4.2 1.0 0.0 4.0 0.0 1.6 9.8 0.9 1.6 0.2 6.5 0.5 0.7 0.8 4.5 0.5 4.1 6.7 4.9 1.8 0.1 0.6 0.3 0.0 7.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 4.4 4.4 8.4 40.1 8.0 13.1 51.0 8.8 48.4 7.9 14.1 16.4 0.0 0.0 1.1 7.2 0.3 0.5 3.1 0.6 0.0 11.4 2.5 2.4 0.8 1.5 2.6 0.0 0.0 0.0 1.5 0.0 5.9 2.3 0.3 5.9 1.5 0.7 0.0 0.4 13.3 2.8 0.2 0.8 0.0 7.0 0.0 2.1 0.0 10.7 0.1 0.0 15.8 0.0 0.0 0.9 1.5 0.2 0.0 1.1 0.0 1.9 1.8 29.7 0.0 6.6 1.2 1.8 0.0 1.2 0.5 6.0 0.0 3.0 3.0 3.6 0.0 0.1 0.9 0.0 1.8 0.3 0.3 0.0 0.2 0.1 0.0 4.5 TRABD PP2447 ENSG00000170638 "TraB domain containing" Q9H4I3 22 50185913-50199598 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000822 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" "HPA000822: AB_10959384" "unprognostic (9.37e-2)" "unprognostic (1.36e-2)" "unprognostic (1.18e-1)" "prognostic favorable (1.19e-5)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-3)" "unprognostic (6.12e-2)" "unprognostic (2.40e-1)" "unprognostic (4.68e-3)" "unprognostic (1.65e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.08e-3)" "unprognostic (1.19e-1)" "unprognostic (2.87e-2)" "unprognostic (2.98e-3)" 19.8 20.7 7.1 27.7 6.9 60.9 18.5 10.1 10.6 23.0 5.9 24.1 18.3 16.8 3.8 40.4 18.8 11.0 21.8 7.0 6.2 26.8 40.8 26.0 32.8 8.5 6.7 18.8 72.7 7.6 21.9 8.4 6.6 29.1 6.3 3.2 29.0 9.6 29.3 23.6 30.7 5.3 6.7 36.9 27.5 20.8 7.2 16.6 24.8 5.0 15.7 22.6 27.0 6.8 62.8 40.9 14.5 24.7 7.8 9.0 35.9 21.4 14.0 17.6 14.9 26.2 29.6 38.3 20.5 10.1 13.7 38.6 18.8 38.1 3.5 27.1 87.1 22.5 71.2 46.0 30.5 45.4 42.7 14.6 22.9 12.9 17.7 10.3 17.9 37.3 27.8 61.7 7.6 70.5 32.5 51.2 21.3 21.3 38.0 87.6 19.7 83.0 13.4 61.5 16.8 28.0 18.4 66.2 31.3 6.1 28.0 47.0 19.4 14.6 36.2 19.2 24.4 73.9 14.1 46.7 18.0 31.5 23.5 16.9 30.5 51.4 21.2 26.5 20.3 13.6 19.1 19.5 32.5 6.7 12.6 15.3 40.6 32.1 16.7 68.7 29.5 22.4 7.1 6.9 10.1 10.6 7.0 6.2 8.5 6.7 6.6 6.7 7.2 6.8 22.2 9.6 19.3 12.1 80.3 42.1 57.4 48.9 33.6 32.6 38.8 30.1 12.0 17.2 31.8 33.1 18.8 25.5 151.7 66.2 27.4 52.3 20.7 17.1 25.1 27.2 18.0 17.4 11.6 62.9 54.5 27.2 77.5 32.4 27.3 31.6 12.8 24.0 46.4 43.7 12.9 55.3 46.8 46.9 59.4 8.8 32.3 69.6 42.7 9.4 111.4 22.5 117.4 14.1 15.3 80.6 67.7 32.4 133.1 125.9 55.0 28.9 19.7 32.8 19.7 20.5 23.7 49.9 31.5 34.3 45.6 30.6 84.3 31.2 71.0 92.5 SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50200979-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 27.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 21.1;Granulosa cells: 34.7;Proximal tubular cells: 41.7;Theca cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" "Intracellular and membrane" Yes NA "Cluster 52: Eosinophils - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.79e-1)" "unprognostic (2.07e-3)" "unprognostic (1.60e-1)" "unprognostic (2.50e-3)" "unprognostic (3.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (5.91e-2)" "unprognostic (1.51e-1)" "unprognostic (5.62e-2)" "unprognostic (8.20e-3)" "unprognostic (8.91e-2)" "unprognostic (1.81e-2)" "unprognostic (7.31e-2)" "unprognostic (1.98e-1)" "unprognostic (2.52e-1)" "prognostic favorable (8.32e-4)" 6.7 6.7 2.3 4.5 3.4 13.9 4.8 11.7 6.8 5.6 2.5 5.3 8.0 5.9 2.8 8.2 5.7 4.1 5.3 3.0 1.1 6.6 27.9 4.7 6.4 4.6 2.7 5.0 13.1 3.0 4.1 3.0 3.7 5.6 2.0 2.9 7.7 4.1 12.3 8.2 6.5 2.4 2.3 6.5 7.0 3.7 3.1 4.4 5.1 4.1 3.9 5.1 6.1 6.0 12.0 7.7 4.2 4.7 5.6 4.1 8.6 11.8 5.6 7.0 5.5 10.6 7.5 7.9 9.2 4.7 3.9 26.2 6.5 10.7 1.4 2.3 29.9 5.7 17.4 6.4 2.8 10.6 6.9 5.4 7.2 4.5 3.5 4.5 5.8 5.3 7.8 5.6 2.9 18.6 5.7 16.4 3.7 2.8 15.6 17.6 5.9 11.8 4.3 15.3 8.4 9.3 12.8 11.3 7.5 2.1 8.7 7.5 9.5 6.0 8.3 6.5 7.1 13.8 3.6 4.7 6.8 6.9 3.5 0.0 1.1 1.3 0.2 0.4 0.5 0.0 0.2 0.5 1.1 0.2 0.1 0.4 0.5 0.0 0.4 0.4 0.2 0.3 2.3 3.4 11.7 6.8 3.0 1.1 4.6 2.7 3.7 2.3 3.1 6.0 11.8 0.0 21.1 0.0 4.1 0.0 0.0 0.0 0.0 0.0 13.3 13.2 0.0 0.0 5.6 9.2 0.0 3.1 12.2 0.0 15.6 3.6 0.0 11.8 10.9 3.0 0.0 0.0 0.0 4.6 2.4 6.0 0.0 15.2 3.8 34.7 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 2.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 4.5 0.0 0.0 41.7 3.6 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 1.9 5.5 29.6 0.0 0.0 TUBGCP6 "DJ402G11.6, GCP6, KIAA1669" ENSG00000128159 "Tubulin gamma complex associated protein 6" Q96RT7 22 50217689-50245023 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043928 Approved NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 50: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "HPA043928: AB_10960352" "unprognostic (4.26e-2)" "unprognostic (1.62e-3)" "unprognostic (2.86e-2)" "unprognostic (2.40e-2)" "unprognostic (1.34e-1)" "unprognostic (2.96e-3)" "unprognostic (2.73e-1)" "unprognostic (2.21e-2)" "unprognostic (2.67e-1)" "unprognostic (1.00e-2)" "prognostic favorable (5.75e-4)" "unprognostic (2.90e-3)" "unprognostic (1.90e-2)" "unprognostic (1.04e-2)" "unprognostic (9.71e-2)" "unprognostic (7.53e-2)" "prognostic favorable (3.18e-5)" 11.1 14.9 10.3 12.3 10.0 13.2 12.2 13.2 14.9 16.6 9.9 12.7 9.8 15.2 6.7 10.1 15.6 10.2 11.3 9.0 8.0 15.1 12.7 11.9 16.4 9.6 7.8 18.3 23.4 12.2 22.2 8.1 7.6 16.4 4.6 5.9 15.9 8.9 14.9 12.9 16.4 6.1 5.7 17.1 15.9 12.4 8.2 15.5 19.7 7.0 10.1 12.7 10.7 11.6 8.0 7.0 12.6 15.2 9.8 9.2 8.6 8.9 5.8 6.2 7.5 5.1 6.6 7.0 6.4 9.1 5.6 9.1 6.3 9.4 2.9 7.2 19.8 6.9 32.7 6.6 6.7 14.6 13.0 13.2 8.4 8.0 6.6 10.5 9.3 14.8 7.2 18.5 5.8 8.3 11.1 12.3 4.2 3.7 4.6 13.4 7.0 14.6 5.2 9.9 4.6 9.1 7.0 12.8 3.7 5.2 6.9 8.3 9.7 9.2 6.6 8.1 6.5 19.4 4.0 8.6 8.0 6.4 6.2 0.7 0.9 0.7 2.2 0.8 1.6 1.0 1.6 2.4 1.0 1.1 1.4 1.7 1.0 1.1 0.7 1.5 2.4 1.2 10.3 10.0 13.2 14.9 9.0 8.0 9.6 7.8 7.6 5.7 8.2 11.6 8.4 9.6 17.2 22.9 10.8 6.4 2.8 6.8 5.2 9.3 9.4 11.0 8.1 7.2 8.3 11.0 16.7 4.6 12.5 8.2 3.9 4.2 2.0 7.2 7.4 6.4 9.0 7.0 13.9 3.6 3.2 8.4 17.9 9.3 6.3 11.5 5.3 7.1 4.4 6.7 12.0 8.1 6.1 9.8 6.2 3.8 9.6 8.6 7.2 9.4 4.6 3.2 9.2 6.6 10.0 4.6 4.9 6.8 11.5 3.9 10.1 2.6 13.2 11.0 6.6 7.8 7.0 10.8 10.0 6.2 5.5 3.4 12.4 10.4 7.7 3.1 HDAC10 DKFZP761B039 ENSG00000100429 "Histone deacetylase 10" Q969S8 22 50245183-50251405 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, DNA damage, DNA recombination, DNA repair" Hydrolase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB045977 Supported NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "CAB045977: AB_11124034" "unprognostic (1.53e-1)" "prognostic favorable (4.46e-4)" "unprognostic (1.43e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.71e-2)" "unprognostic (3.70e-2)" "unprognostic (6.15e-3)" "unprognostic (5.48e-2)" "unprognostic (3.28e-1)" "unprognostic (2.56e-2)" "prognostic favorable (9.25e-4)" "unprognostic (4.93e-2)" "prognostic unfavorable (4.74e-11)" "unprognostic (2.21e-2)" "unprognostic (2.52e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" 8.9 9.8 4.9 6.0 4.8 9.6 7.1 3.6 10.3 9.3 5.4 9.9 6.6 6.8 1.2 10.7 8.0 3.9 4.9 5.1 4.5 11.5 16.8 8.5 6.7 5.1 4.5 7.6 11.2 2.2 13.2 3.3 4.5 10.8 1.5 0.2 8.7 2.8 5.1 9.2 12.6 1.9 3.9 17.2 11.4 2.2 5.1 4.2 9.5 0.5 2.8 7.2 8.1 4.1 6.1 3.3 0.9 5.0 4.2 3.3 11.4 4.2 3.4 2.3 1.4 6.4 6.6 4.0 5.7 3.1 2.2 10.2 2.1 5.9 0.5 5.4 5.7 8.5 10.1 10.4 7.5 10.9 27.0 7.0 4.4 2.3 1.3 4.8 4.2 7.8 6.3 6.1 2.0 18.7 5.8 25.9 2.0 6.5 7.4 13.4 3.3 24.6 3.8 10.5 2.7 6.5 4.2 1.4 7.2 1.2 10.8 15.8 7.4 3.9 5.7 6.7 2.5 7.8 2.6 3.6 6.4 6.7 2.8 0.4 1.6 2.5 0.7 1.8 0.6 0.4 0.3 0.5 1.3 0.4 0.3 0.3 0.8 0.5 1.0 1.2 0.6 1.1 4.9 4.8 3.6 10.3 5.1 4.5 5.1 4.5 4.5 3.9 5.1 4.1 13.9 0.0 3.4 12.1 17.7 8.7 4.8 10.3 9.1 5.7 14.3 13.6 0.6 12.8 6.8 14.7 16.7 11.6 28.6 25.4 7.9 6.3 3.3 9.3 6.9 8.5 20.9 8.4 8.9 3.8 16.2 8.1 32.6 9.0 5.1 16.6 10.0 7.9 21.1 0.0 10.6 17.3 6.1 20.0 13.3 8.3 11.1 19.9 8.8 4.7 18.1 2.9 20.6 3.5 2.4 6.1 17.8 7.9 12.3 3.4 29.2 16.3 14.3 6.5 0.0 3.0 6.3 1.0 2.3 13.1 9.5 10.3 26.0 13.5 18.3 4.4 MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "skeletal muscle: 279.7;tongue: 120.9" "Cell type enhanced" "Detected in many" "Adipocytes: 23.1;Astrocytes: 22.9;Endothelial cells: 15.8;Hepatic stellate cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" Cytosol "CAB025483: , HPA054562: AB_2682524" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (4.53e-3)" "unprognostic (1.54e-1)" "unprognostic (3.22e-2)" "unprognostic (6.35e-3)" "unprognostic (3.90e-3)" "unprognostic (3.16e-2)" "unprognostic (6.02e-2)" "unprognostic (5.70e-2)" "unprognostic (3.48e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (5.00e-6)" "unprognostic (2.57e-1)" "unprognostic (8.88e-2)" "unprognostic (1.11e-2)" "unprognostic (4.28e-3)" 11.0 2.3 15.6 3.8 16.5 1.3 7.9 15.5 21.2 11.4 9.2 4.7 3.5 19.0 9.8 6.3 11.2 4.4 15.7 15.1 16.5 10.7 1.4 6.8 4.1 17.1 14.9 10.6 1.8 4.3 25.1 4.1 14.6 10.0 1.1 1.4 4.3 6.9 279.7 1.5 4.4 8.6 14.6 4.3 5.0 4.6 15.2 0.9 3.2 120.9 1.4 6.0 5.9 13.9 23.2 13.9 5.3 16.3 12.4 13.5 7.5 17.5 15.1 28.2 18.3 19.6 7.2 45.1 23.4 19.6 16.8 15.4 24.3 3.4 5.5 12.8 34.0 29.2 46.7 24.9 37.7 28.4 54.5 29.8 6.0 7.2 0.0 16.8 33.2 4.0 26.3 38.5 13.4 12.8 0.0 35.4 15.9 7.6 22.5 41.4 14.2 43.9 17.5 3.0 18.0 6.5 13.3 0.5 22.1 4.2 7.1 29.6 18.7 28.5 26.1 6.6 11.2 9.3 7.3 24.5 7.2 24.7 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.6 16.5 15.5 21.2 15.1 16.5 17.1 14.9 14.6 14.6 15.2 13.9 23.1 0.0 3.2 22.9 1.6 0.8 0.7 3.3 1.2 5.5 1.2 1.3 8.8 4.3 0.8 0.0 0.0 0.3 0.9 0.3 1.9 0.5 0.3 0.6 10.0 15.8 1.8 1.7 9.8 0.0 2.8 5.3 2.6 0.7 10.8 0.6 20.7 0.9 6.3 1.7 6.5 0.2 8.2 2.2 0.8 1.9 6.5 2.2 0.0 6.5 0.6 8.1 0.0 5.0 0.9 0.5 0.0 3.8 2.8 3.6 0.4 8.0 0.9 2.2 6.6 3.3 3.0 0.7 12.1 0.8 0.6 0.4 2.2 3.2 0.3 0.2 MAPK11 "p38-2, p38Beta, PRKM11, SAPK2" ENSG00000185386 "Mitogen-activated protein kinase 11" Q15759 22 50263713-50270767 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 70.9" "Cell type enhanced" "Detected in many" "Adipocytes: 29.5;Astrocytes: 16.6;Endothelial cells: 21.1;Excitatory neurons: 15.8;Hepatic stellate cells: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012961, HPA045069" Approved Approved Mitochondria NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria "CAB012961: AB_2533144, HPA045069: AB_2679207" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (1.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.02e-1)" "unprognostic (5.84e-2)" "unprognostic (5.89e-2)" "unprognostic (2.46e-1)" "unprognostic (4.96e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (6.02e-6)" "unprognostic (9.84e-2)" "unprognostic (4.25e-2)" "unprognostic (9.16e-2)" "unprognostic (2.10e-2)" 27.5 6.8 52.3 7.9 56.0 1.1 24.0 48.2 70.9 15.1 40.6 7.3 1.9 15.5 5.8 9.4 16.7 8.7 18.9 55.2 49.6 18.6 4.8 16.8 9.4 48.2 47.2 12.5 5.7 5.4 28.4 8.3 48.2 18.2 2.6 8.6 7.2 7.2 6.4 7.5 8.3 9.4 47.4 16.3 10.9 6.1 50.2 3.5 11.0 5.8 6.1 11.6 12.3 51.0 2.8 6.8 7.4 27.8 9.5 14.3 0.2 10.2 7.4 6.8 2.7 2.8 5.2 0.0 8.7 9.9 11.3 6.9 4.9 4.2 0.5 13.9 3.4 10.1 10.4 0.6 10.9 2.5 15.0 19.9 12.3 1.9 0.8 7.7 15.2 10.6 8.1 26.8 6.9 12.4 0.5 9.4 0.6 8.4 7.7 26.7 0.1 9.9 10.3 0.0 6.8 18.4 9.0 3.7 7.7 0.9 12.2 7.9 24.0 20.4 16.5 1.5 3.7 1.2 3.2 11.8 10.4 2.9 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 52.3 56.0 48.2 70.9 55.2 49.6 48.2 47.2 48.2 47.4 50.2 51.0 29.5 0.0 1.1 16.6 2.2 1.9 1.8 3.2 8.0 3.3 1.1 1.5 6.6 1.5 1.7 0.0 6.2 0.0 1.8 0.1 1.9 1.0 4.7 0.6 1.8 21.1 0.0 0.4 15.8 0.2 0.4 2.7 0.5 1.7 0.0 0.1 20.0 2.1 0.3 0.0 3.6 0.2 2.0 1.3 2.1 9.7 3.1 0.5 5.4 13.1 0.1 5.9 0.0 1.0 0.9 0.7 0.0 2.2 1.6 2.9 0.0 1.9 1.3 11.4 0.0 0.6 1.8 1.3 3.2 1.8 1.3 0.0 3.3 0.7 0.1 1.1 PLXNB2 "KIAA0315, MM1, PLEXB2" ENSG00000196576 "Plexin B2" O15031 22 50274979-50307646 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 296.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "classical monocyte: 11.1;intermediate monocyte: 16.4;myeloid DC: 8.3;non-classical monocyte: 21.2;plasmacytoid DC: 6.6" "Group enriched" "Detected in many" 25 "dendritic cells: 8.3;monocytes: 21.2" "Cell line enhanced" "Detected in many" "SK-BR-3: 306.0" "Low region specificity" "Detected in all" HPA003100 Uncertain NA NA 78000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "HPA003100: AB_1079638" "unprognostic (4.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.28e-2)" "unprognostic (4.96e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (8.47e-3)" "unprognostic (9.84e-2)" "unprognostic (3.05e-2)" "prognostic favorable (4.75e-4)" "unprognostic (1.61e-2)" "unprognostic (9.41e-3)" "unprognostic (6.05e-2)" 28.1 42.9 12.5 31.2 11.5 14.6 25.0 43.2 14.7 38.8 61.2 45.8 45.0 44.0 7.7 48.6 50.6 51.5 20.1 9.8 12.3 42.5 33.2 40.2 22.8 21.1 22.9 49.6 47.5 22.5 33.8 35.7 16.9 40.0 16.4 9.3 53.0 45.6 7.0 50.2 50.3 20.2 13.2 74.2 87.4 18.6 16.7 7.8 53.8 3.1 15.3 33.3 41.3 15.5 77.0 125.0 58.2 78.7 35.2 43.2 98.9 104.8 55.8 36.8 36.1 87.0 102.0 59.9 114.1 86.8 22.6 145.9 10.2 77.5 9.1 10.8 50.3 11.2 233.2 64.3 79.2 2.0 54.6 67.8 117.5 39.1 29.9 64.8 30.0 0.1 15.9 14.3 38.7 132.4 1.1 21.0 15.5 45.9 31.3 64.2 97.8 18.8 39.4 237.5 29.6 53.6 103.0 306.0 22.6 16.9 119.9 72.0 64.9 76.1 112.6 39.7 37.9 8.1 1.5 11.0 60.4 3.5 101.5 0.0 11.1 0.0 0.0 16.4 0.2 0.0 0.0 0.0 8.3 0.0 0.0 0.1 0.4 0.1 21.2 6.6 0.5 7.7 12.5 11.5 43.2 14.7 9.8 12.3 21.1 22.9 16.9 13.2 16.7 15.5 15.2 64.1 54.5 33.0 6.2 22.9 22.7 70.6 23.9 15.5 48.2 40.8 15.5 62.9 94.4 136.1 16.7 3.1 11.8 172.0 3.9 93.1 9.0 87.8 33.4 24.8 49.7 2.1 13.5 57.5 29.3 28.7 296.2 72.6 5.1 43.2 21.4 58.8 36.3 13.5 9.3 77.9 40.7 46.8 38.2 4.3 24.2 49.9 14.2 24.4 45.1 54.1 2.1 4.5 1.6 117.5 111.4 19.2 4.9 54.3 110.5 36.4 154.6 10.4 26.3 18.9 35.8 2.2 2.4 34.5 25.1 6.4 4.1 48.5 56.5 45.1 DENND6B "AFI1B, FAM116B, MGC33692" ENSG00000205593 "DENN domain containing 6B" Q8NEG7 22 50309030-50327012 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 42.1;Late spermatids: 58.7;monocytes: 39.4;Respiratory ciliated cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 6.9;RPMI-8226: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018934, HPA021653, HPA029570" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA018934: AB_1848365, HPA021653: AB_1848366, HPA029570: AB_10602131" "unprognostic (2.50e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.41e-4)" "prognostic favorable (5.93e-5)" "unprognostic (9.39e-2)" "unprognostic (3.17e-1)" "unprognostic (1.89e-3)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (4.50e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (8.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-2)" 2.4 3.8 10.6 2.3 10.8 1.0 3.4 8.0 14.4 6.2 8.6 3.9 1.1 5.2 2.5 2.5 13.4 3.2 1.7 10.3 9.5 7.6 1.7 4.7 2.9 9.4 9.1 4.0 5.4 2.7 13.6 1.0 9.5 5.5 0.9 4.2 3.6 3.6 0.7 2.6 3.9 1.7 6.9 4.5 3.3 6.7 9.6 0.8 6.7 0.6 1.7 2.6 3.5 7.7 0.5 1.8 3.9 4.3 1.0 3.7 0.0 0.8 1.9 0.5 0.3 0.1 2.8 6.9 1.7 1.9 0.2 3.4 0.1 0.1 0.2 1.7 1.0 1.2 3.5 0.2 0.9 0.2 3.0 3.1 4.2 0.1 0.6 3.8 0.8 0.1 1.5 1.2 0.9 3.0 0.0 0.6 0.3 2.0 0.2 1.0 0.0 10.0 4.9 1.6 1.7 3.1 2.1 2.7 0.3 0.2 4.3 1.0 0.9 0.7 0.6 0.6 0.1 1.0 0.2 1.0 1.7 0.8 0.8 0.2 0.8 0.0 0.1 1.0 0.2 0.2 0.1 0.2 0.5 0.2 0.1 0.2 0.1 0.3 1.3 0.4 0.1 0.3 10.6 10.8 8.0 14.4 10.3 9.5 9.4 9.1 9.5 6.9 9.6 7.7 4.5 3.2 4.1 16.3 14.9 1.1 3.6 6.1 5.7 6.2 5.4 5.8 1.3 11.5 8.3 5.5 22.9 0.3 9.5 3.9 3.9 6.5 24.7 42.1 4.6 5.7 10.2 4.4 20.3 1.8 0.6 4.2 9.2 5.7 5.7 2.8 4.2 1.0 13.7 1.7 13.7 3.3 4.1 24.2 7.8 58.7 2.5 20.0 5.4 2.8 39.4 5.6 5.2 9.0 2.5 2.6 2.1 2.6 33.2 2.4 14.0 17.8 65.5 17.5 0.0 2.5 3.0 24.7 22.2 1.6 0.6 1.0 8.4 3.1 3.6 2.3 PPP6R2 "dJ579N16.1, KIAA0685, SAP190, SAPS2" ENSG00000100239 "Protein phosphatase 6 regulatory subunit 2" O75170 22 50343304-50445090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030656, CAB034919" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Vesicles, Cytosol" "CAB034919: AB_2183817, HPA030656: AB_10602926" "unprognostic (1.24e-1)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.70e-5)" "unprognostic (2.17e-1)" "unprognostic (3.79e-3)" "unprognostic (2.32e-1)" "unprognostic (1.30e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-2)" "prognostic favorable (7.51e-4)" "unprognostic (6.89e-2)" "unprognostic (1.42e-2)" "unprognostic (1.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (7.77e-3)" 21.9 35.6 23.5 20.9 27.3 21.4 23.2 24.3 32.2 23.7 19.2 28.5 24.5 25.4 11.5 28.3 23.8 18.0 36.7 25.4 19.7 29.6 72.4 25.2 27.3 26.9 22.2 24.8 29.0 21.4 41.0 14.8 21.8 31.4 11.8 12.6 27.9 17.1 65.8 27.6 28.7 14.0 18.2 32.4 30.1 62.7 26.0 25.8 30.8 31.7 16.5 23.9 22.3 25.8 30.9 17.8 27.3 34.8 19.7 21.0 24.4 30.1 31.9 31.5 31.7 15.0 18.7 36.9 14.5 30.0 17.4 24.6 16.9 22.4 11.8 19.3 30.9 19.8 37.7 37.7 25.6 46.9 52.1 31.2 23.8 19.0 10.1 24.8 27.8 30.8 20.5 31.5 23.2 50.0 32.3 33.9 11.3 19.5 21.9 44.8 20.9 24.3 23.1 36.1 17.0 23.1 31.0 47.6 25.0 10.1 17.2 35.2 32.5 29.3 26.4 24.6 20.3 33.6 8.7 32.7 30.6 22.6 41.2 4.0 8.6 5.8 9.0 9.4 10.4 7.9 6.2 9.6 8.8 8.4 5.9 7.9 13.7 5.9 6.8 11.0 13.3 8.5 23.5 27.3 24.3 32.2 25.4 19.7 26.9 22.2 21.8 18.2 26.0 25.8 28.5 22.4 20.6 79.0 32.0 8.8 14.4 12.9 22.8 43.7 25.5 21.8 19.2 37.1 17.1 27.6 56.3 17.3 39.9 39.8 31.3 19.3 84.0 30.8 39.0 18.1 26.9 19.8 83.0 32.5 11.8 15.3 35.2 34.8 31.8 23.9 18.9 65.1 16.0 65.6 80.8 23.0 16.2 25.3 8.8 48.6 19.6 23.4 10.6 61.8 32.1 25.0 50.4 52.8 59.9 33.3 29.0 19.9 42.0 19.4 27.0 23.6 17.9 43.2 26.3 16.9 18.7 78.5 47.1 17.9 8.5 28.5 28.4 17.8 25.2 17.5 SBF1 "DENND7A, MTMR5" ENSG00000100241 "SET binding factor 1" O95248 22 50445000-50475035 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074004 Supported "Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" "Nuclear bodies" "HPA074004: AB_2732249" "unprognostic (4.79e-2)" "unprognostic (1.37e-1)" "unprognostic (7.39e-2)" "unprognostic (4.87e-2)" "unprognostic (6.11e-2)" "prognostic favorable (3.46e-5)" "unprognostic (2.21e-3)" "unprognostic (1.14e-1)" "unprognostic (2.32e-2)" "unprognostic (3.60e-3)" "unprognostic (1.78e-1)" "unprognostic (1.75e-2)" "unprognostic (2.42e-2)" "unprognostic (3.29e-2)" "unprognostic (1.12e-1)" "unprognostic (1.74e-2)" "unprognostic (2.05e-1)" 26.8 32.3 50.8 22.3 57.3 20.6 24.2 31.8 72.4 25.9 9.2 32.9 14.8 29.5 3.2 43.9 27.2 10.6 38.7 70.1 28.5 30.5 23.4 26.8 28.8 52.0 39.2 30.4 48.0 7.1 28.6 8.8 46.5 28.5 4.9 6.5 26.9 11.6 75.7 42.2 38.6 8.8 32.8 35.4 30.1 111.2 44.1 32.7 62.3 14.4 14.7 28.3 27.3 63.5 34.3 28.2 24.0 32.9 24.3 18.6 65.9 23.5 20.1 21.6 17.7 39.0 23.7 78.1 16.7 27.9 23.9 31.4 19.9 28.7 5.3 28.6 76.0 17.6 59.6 50.7 41.7 54.7 26.1 25.0 44.6 28.1 21.0 17.0 14.8 41.6 28.8 20.8 15.0 42.6 54.8 52.4 10.1 26.1 31.7 71.0 45.6 48.3 12.8 27.3 19.1 46.0 36.5 35.5 47.7 10.5 20.7 25.2 25.1 33.9 49.6 24.3 29.7 38.1 13.4 37.6 38.8 22.1 32.7 0.5 1.3 2.1 4.4 1.3 2.4 2.6 3.0 3.5 1.6 1.6 2.2 3.6 1.9 1.9 2.6 5.6 2.6 2.3 50.8 57.3 31.8 72.4 70.1 28.5 52.0 39.2 46.5 32.8 44.1 63.5 5.7 6.4 11.8 10.7 13.7 13.4 4.6 9.3 6.8 15.5 11.3 9.1 7.6 4.3 9.4 3.7 10.4 4.9 21.4 19.9 1.9 7.2 32.8 10.3 8.9 5.6 3.6 8.6 11.3 12.5 7.9 10.6 24.5 11.4 1.3 20.4 5.7 9.1 6.9 11.8 10.9 13.2 10.2 6.9 10.7 21.4 6.5 9.5 5.4 5.6 10.8 6.9 21.6 11.1 31.7 19.9 8.1 6.0 15.6 11.6 16.0 7.7 11.1 10.0 6.6 12.3 11.6 25.5 23.5 21.3 14.6 11.5 19.8 12.2 12.3 10.1 ADM2 "AM2, FLJ21135" ENSG00000128165 "Adrenomedullin 2" Q7Z4H4 22 50481543-50486440 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 8.3;pancreas: 15.5;thyroid gland: 11.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 10.0;Gastric mucus-secreting cells: 7.1;Intestinal goblet cells: 7.1;Pancreatic endocrine cells: 9.4;Proximal enterocytes: 7.4;Proximal tubular cells: 28.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 37.1;hTCEpi: 23.8;Karpas-707: 38.2;SK-MEL-30: 25.9;U-266/70: 25.6" "Not detected" "Not detected" "Secreted to blood" NA NA 61300 "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (1.30e-2)" "unprognostic (4.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-1)" "unprognostic (2.67e-1)" "unprognostic (3.15e-1)" "unprognostic (4.62e-3)" "unprognostic (7.26e-3)" "unprognostic (1.50e-1)" "unprognostic (3.44e-1)" "unprognostic (7.20e-2)" "unprognostic (9.41e-2)" "unprognostic (7.30e-3)" "unprognostic (1.17e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.72e-4)" "unprognostic (1.06e-2)" 0.3 0.2 0.2 1.7 0.3 0.4 0.4 0.6 0.4 0.9 0.0 1.1 3.7 0.1 1.7 3.0 0.2 1.2 0.1 0.1 0.1 8.3 3.8 0.8 2.6 0.2 0.2 0.0 15.5 0.3 0.4 0.2 0.2 2.6 0.6 0.0 5.6 0.4 0.0 0.4 2.9 0.2 0.0 1.1 4.0 0.6 0.4 1.0 11.6 0.0 1.9 0.3 0.3 0.2 1.8 0.3 0.5 2.0 1.2 2.1 7.0 9.1 0.8 1.3 2.9 3.9 1.5 0.0 1.3 7.9 1.5 1.4 2.0 1.2 0.5 17.3 0.0 0.1 0.5 2.8 37.1 3.8 2.5 7.5 23.8 4.1 8.6 0.1 0.1 10.1 2.4 38.2 0.3 5.8 0.3 0.7 1.2 10.7 5.7 0.0 0.0 15.1 1.7 0.2 1.0 4.0 0.1 5.5 25.9 1.2 7.6 12.2 0.0 0.0 8.1 0.0 0.0 25.6 4.2 5.0 0.3 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.6 0.4 0.1 0.1 0.2 0.2 0.2 0.0 0.4 0.2 0.2 0.0 3.0 0.0 2.5 0.0 0.9 1.0 0.0 0.0 3.6 1.8 1.4 1.5 0.5 0.0 0.0 0.1 0.6 3.9 3.9 2.6 0.0 0.5 0.4 0.3 1.2 0.0 0.0 10.0 0.7 0.2 7.1 1.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 7.1 0.0 0.0 0.3 0.2 0.0 0.4 1.8 0.0 0.6 0.0 1.0 0.0 0.0 9.4 1.4 0.0 3.1 2.0 7.4 28.1 0.1 0.0 0.0 1.1 0.7 0.2 1.0 0.0 0.4 1.0 1.2 0.0 1.1 0.9 MIOX ALDRL6 ENSG00000100253 "Myo-inositol oxygenase" Q9UGB7 22 50486784-50490648 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "kidney: 700.9" "Cell type enriched" "Detected in some" 10 "Proximal tubular cells: 4564.6" "Cancer enriched" "Detected in many" 16 "renal cancer: 56.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 24.9;Hep G2: 5.7;Karpas-707: 12.8;U-266/70: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039451, HPA039562" Enhanced NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA039451: AB_2676513, HPA039562: AB_2676574" "unprognostic (2.11e-1)" "unprognostic (4.32e-2)" "unprognostic (2.22e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (5.25e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-3)" "unprognostic (2.84e-1)" "unprognostic (4.72e-2)" "unprognostic (1.85e-2)" "unprognostic (9.83e-2)" "prognostic favorable (2.60e-6)" "unprognostic (1.77e-1)" "unprognostic (1.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.23e-2)" 0.2 0.1 0.1 0.3 0.2 0.2 0.0 0.8 0.5 0.0 0.2 0.8 0.2 0.0 0.2 0.1 0.0 5.3 0.0 0.2 0.2 700.9 0.4 0.0 0.7 0.2 0.2 0.0 1.2 0.0 0.1 0.1 0.3 0.5 0.0 0.1 0.3 0.1 0.0 0.3 0.2 0.0 0.1 0.2 1.1 0.2 0.2 0.2 14.7 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.3 0.2 0.1 2.0 0.2 0.0 0.0 0.1 0.1 0.2 0.1 0.6 0.4 0.0 0.2 0.2 0.0 0.0 24.9 0.0 0.2 0.4 5.7 2.8 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 1.1 0.1 12.8 0.0 1.2 0.0 0.1 0.2 0.5 0.4 0.1 0.1 0.1 2.6 0.1 0.1 0.3 0.0 0.0 0.6 0.5 0.1 1.4 0.0 0.0 0.5 0.1 0.1 7.8 0.7 0.3 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.8 0.5 0.2 0.2 0.2 0.2 0.3 0.1 0.2 0.3 0.2 0.0 1.7 0.0 13.0 0.8 0.9 0.1 0.0 0.6 0.7 0.8 0.1 1.5 0.0 99.3 0.0 0.0 0.3 0.3 424.6 0.0 0.0 0.1 0.2 0.2 1.2 0.0 0.0 0.9 0.1 0.3 0.0 0.2 0.0 0.1 0.4 0.3 0.1 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 23.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 4564.6 0.0 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.3 7.8 0.0 0.1 0.9 LMF2 "TMEM112B, TMEM153" ENSG00000100258 "Lipase maturation factor 2" Q9BU23 22 50502949-50507702 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062626 Approved Approved Centrosome NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Centrosome "HPA062626: AB_2684812" "unprognostic (2.69e-1)" "prognostic favorable (3.47e-4)" "unprognostic (8.67e-2)" "unprognostic (2.25e-2)" "unprognostic (1.68e-2)" "unprognostic (5.13e-2)" "unprognostic (1.21e-2)" "unprognostic (2.70e-2)" "unprognostic (5.11e-2)" "unprognostic (2.90e-1)" "unprognostic (2.97e-2)" "unprognostic (3.12e-3)" "unprognostic (8.49e-2)" "unprognostic (1.47e-1)" "unprognostic (2.08e-1)" "unprognostic (2.54e-2)" "unprognostic (8.75e-2)" 50.8 43.9 21.2 20.6 21.6 33.6 46.4 21.4 30.0 49.7 33.6 40.4 25.9 43.9 8.3 48.0 42.0 15.2 37.5 21.6 23.9 48.7 56.6 46.8 22.4 25.7 21.6 47.8 180.8 12.9 63.4 18.0 23.6 51.2 5.6 3.7 49.5 20.0 23.7 36.6 51.4 9.3 21.9 60.6 38.0 42.0 21.7 13.1 56.7 7.6 9.4 45.2 44.5 23.9 48.9 36.0 20.1 38.4 28.6 24.4 46.8 85.4 44.5 53.7 60.0 35.9 24.8 21.4 22.6 45.2 23.9 57.3 6.8 27.0 7.4 17.1 74.7 12.0 69.3 38.4 35.8 22.4 45.1 36.0 24.6 36.7 9.0 23.1 30.1 16.5 14.4 70.0 23.7 35.1 15.9 26.4 12.0 12.4 44.4 35.7 32.3 58.9 22.0 26.1 18.0 26.5 58.2 49.8 40.1 9.7 28.6 15.6 44.3 75.3 42.8 54.6 4.3 26.9 9.4 13.1 54.8 13.6 62.9 16.3 17.9 22.4 26.1 23.5 19.6 13.4 21.6 24.4 18.6 8.6 12.3 13.2 16.5 16.7 20.5 33.8 21.2 18.6 21.2 21.6 21.4 30.0 21.6 23.9 25.7 21.6 23.6 21.9 21.7 23.9 42.0 12.8 10.8 13.4 26.4 18.6 17.1 37.5 19.9 15.7 23.1 18.7 11.4 28.6 24.5 14.7 22.9 64.4 43.1 55.6 3.9 37.1 9.4 7.6 21.7 25.7 15.0 22.9 14.9 74.9 106.4 39.9 27.5 17.3 15.8 32.7 27.8 33.6 43.1 11.8 11.6 29.4 18.3 21.6 26.7 20.5 29.2 26.1 24.9 13.1 21.5 23.3 40.2 12.5 10.1 30.8 55.7 25.6 49.9 10.8 74.4 19.3 9.4 16.0 19.7 17.9 29.6 12.6 20.1 29.9 17.3 28.5 34.8 32.0 34.2 15.0 NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cytokinetic bridge" "HPA067932: AB_2685926, HPA069056: AB_2686076" "unprognostic (2.01e-1)" "prognostic favorable (2.24e-8)" "unprognostic (3.65e-2)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.57e-2)" "prognostic unfavorable (8.25e-4)" "unprognostic (2.92e-2)" "unprognostic (8.66e-2)" "unprognostic (1.10e-1)" "unprognostic (2.26e-2)" "unprognostic (6.31e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (1.41e-1)" "unprognostic (3.00e-1)" 25.7 21.9 32.9 24.5 33.6 78.8 26.9 32.7 39.2 31.8 25.4 29.3 17.7 29.8 12.4 30.3 30.0 13.0 36.7 32.0 30.9 26.6 27.6 28.2 27.6 32.6 29.0 37.6 40.7 16.7 38.6 17.1 28.7 28.4 11.7 15.5 25.7 16.6 30.7 32.6 28.4 14.7 27.5 33.2 30.2 52.3 28.5 29.6 28.9 19.3 20.2 25.9 26.9 33.5 60.7 32.1 53.8 57.1 15.8 18.4 71.6 45.8 31.6 81.8 89.5 67.2 41.4 68.8 25.5 32.9 45.5 47.1 49.0 44.2 23.5 40.3 82.8 39.8 86.7 63.6 19.1 90.3 69.5 16.1 27.6 64.4 22.2 12.2 26.2 59.4 51.5 132.5 33.4 83.9 61.7 109.9 39.3 34.9 37.9 103.3 71.0 77.2 23.8 40.6 35.6 47.5 36.7 55.4 44.3 16.5 37.5 86.7 17.6 64.2 80.5 54.4 72.3 67.7 45.8 110.1 48.8 45.7 62.3 11.9 9.8 18.2 18.7 11.6 22.9 16.0 19.4 19.1 8.0 14.2 19.9 17.3 11.4 13.9 14.4 11.8 19.3 15.5 32.9 33.6 32.7 39.2 32.0 30.9 32.6 29.0 28.7 27.5 28.5 33.5 10.1 22.4 24.5 12.1 15.9 18.9 23.8 17.5 6.2 18.3 11.5 12.6 19.6 15.7 10.4 9.2 4.2 36.3 15.5 24.6 15.6 16.6 36.8 8.5 7.5 12.9 13.1 31.5 8.6 23.5 55.1 13.8 14.8 14.5 17.1 16.3 8.9 10.6 19.3 8.4 8.8 18.8 6.1 7.9 16.3 111.5 17.4 9.2 12.4 3.7 16.2 14.7 18.6 3.0 8.2 17.3 13.5 17.3 26.6 15.2 18.4 9.5 5.9 16.1 19.7 17.8 16.9 36.2 39.7 10.9 18.5 31.5 15.9 7.6 22.6 18.2 SCO2 "MYP6, SCO1L" ENSG00000284194 "Synthesis of cytochrome C oxidase 2" O43819 22 50523568-50526461 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Cardiomyopathy, Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 112.2;Paneth cells: 131.5;Proximal enterocytes: 110.7;Suprabasal keratinocytes: 98.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046943, HPA056254" Uncertain Approved Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "HPA046943: AB_2732536, HPA056254: AB_2683080" 16.8 10.3 14.0 13.4 13.8 36.5 7.8 14.4 16.8 6.8 18.2 22.0 25.6 3.6 4.7 12.3 15.8 7.7 10.3 14.3 14.4 8.1 18.4 14.4 9.1 18.8 19.1 1.8 11.5 7.2 1.5 8.3 17.5 5.1 10.5 0.1 21.3 6.7 10.2 11.0 19.7 12.7 16.4 11.4 10.2 4.1 17.4 11.2 2.3 10.1 10.3 13.0 2.5 17.4 37.4 29.9 1.3 12.5 17.7 24.2 18.7 19.5 24.1 38.0 32.8 35.3 17.8 42.7 19.7 22.6 9.6 36.0 19.3 31.5 6.1 7.6 82.5 13.8 20.2 46.7 44.6 43.8 18.3 38.4 48.6 19.4 15.8 10.6 24.4 5.8 15.6 32.9 16.8 55.7 13.3 76.5 11.0 15.5 54.8 26.1 7.5 65.0 29.6 21.3 16.6 23.7 24.4 70.7 63.5 1.3 26.1 24.7 25.8 16.3 22.6 30.2 22.2 26.1 15.6 29.2 35.7 28.7 14.5 19.1 21.8 12.2 43.9 19.9 42.2 40.1 38.9 44.1 34.9 33.4 29.2 32.6 21.6 27.7 21.1 56.2 37.0 37.7 14.0 13.8 14.4 16.8 14.3 14.4 18.8 19.1 17.5 16.4 17.4 17.4 0.0 3.2 2.7 2.9 20.0 85.7 21.6 75.5 44.3 7.3 0.1 0.0 16.8 21.5 31.4 0.0 2.1 0.0 5.3 112.2 0.0 0.0 15.1 0.1 0.2 13.8 25.8 14.1 2.7 0.0 0.0 14.1 24.5 0.1 15.9 0.0 18.2 53.5 0.0 11.8 2.7 63.2 48.8 28.2 63.6 25.6 16.4 29.2 42.7 5.6 47.3 5.5 25.7 5.5 1.4 0.1 131.5 10.9 32.1 40.0 110.7 0.1 42.6 7.1 0.0 30.4 29.5 17.3 35.7 56.1 98.9 0.0 14.9 0.1 90.7 22.3 TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 643.9;Hofbauer cells: 477.4;Macrophages: 561.7;monocytes: 2174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 135.8;eosinophil: 74.9;intermediate monocyte: 98.4;myeloid DC: 39.5;neutrophil: 114.1;non-classical monocyte: 77.1" "Group enriched" "Detected in all" 10 "dendritic cells: 39.5;granulocytes: 114.1;monocytes: 135.8" "Cell line enhanced" "Detected in many" "CAPAN-2: 40.0;HHSteC: 95.2;Karpas-707: 68.6;U-266/70: 68.6" "Not detected" "Not detected" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 11000000 "Cluster 52: Eosinophils - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: AB_563953, HPA000530: AB_2666017, HPA001072: AB_1080274" "unprognostic (7.02e-3)" "unprognostic (1.00e-1)" "unprognostic (3.61e-1)" "prognostic favorable (4.34e-5)" "unprognostic (7.60e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-1)" "unprognostic (7.17e-2)" "unprognostic (4.64e-2)" "unprognostic (1.33e-1)" "unprognostic (3.31e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (3.50e-8)" "unprognostic (1.32e-1)" "unprognostic (4.02e-2)" "unprognostic (1.52e-2)" "unprognostic (4.60e-2)" 46.8 19.5 6.1 77.7 6.0 22.0 37.9 7.1 7.9 32.2 12.7 20.4 26.1 7.8 0.5 58.5 30.0 7.2 26.7 6.4 8.6 38.2 82.0 63.4 31.5 22.1 18.3 4.0 13.8 4.5 8.8 15.4 15.9 21.0 3.6 0.0 40.0 5.6 10.7 24.5 32.5 9.1 10.9 86.1 31.2 3.0 18.0 15.6 25.4 1.6 15.3 22.9 27.0 12.2 27.0 2.5 0.4 0.8 1.8 2.2 5.1 3.7 0.5 6.1 17.4 0.1 40.0 1.8 4.1 5.8 1.3 21.0 0.2 1.0 0.0 9.0 16.5 1.8 3.9 3.5 95.2 1.3 26.9 4.7 4.6 5.4 0.0 0.1 0.1 0.5 2.8 68.6 0.9 1.9 1.5 9.9 0.6 1.9 9.1 5.7 0.4 35.1 0.3 1.2 0.7 5.6 22.9 17.3 6.5 0.2 4.2 13.8 6.7 0.8 4.7 1.5 1.5 68.6 15.9 5.7 1.9 1.5 1.6 19.5 135.8 74.9 2.0 98.4 1.2 6.7 2.9 1.2 39.5 6.9 1.6 1.3 114.1 9.5 77.1 9.3 3.1 10.1 6.1 6.0 7.1 7.9 6.4 8.6 22.1 18.3 15.9 10.9 18.0 12.2 122.6 12.8 29.0 0.3 122.9 58.5 57.4 169.9 53.5 3.4 101.5 90.8 3.2 50.1 88.6 33.1 4.2 17.2 65.8 154.8 29.4 340.2 2.2 55.7 56.0 55.7 16.8 19.6 0.3 643.9 300.8 81.9 38.7 59.2 53.4 3.0 38.2 93.0 477.4 0.0 0.4 50.2 24.4 371.8 409.4 8.7 5.0 561.7 113.8 4.7 2174.6 2.9 71.1 0.5 0.2 364.0 86.4 1.9 102.1 109.8 214.5 105.1 78.0 6.6 26.3 93.3 62.4 1.5 8.0 71.7 56.7 33.5 62.5 3.7 51.1 76.0 ODF3B FAP123 ENSG00000177989 "Outer dense fiber of sperm tails 3B" A8MYP8 22 50529710-50532580 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 88.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 455.4;Late spermatids: 807.7;Respiratory ciliated cells: 417.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 92.0;intermediate monocyte: 75.6;myeloid DC: 55.5;neutrophil: 56.2;non-classical monocyte: 53.6" "Group enriched" "Detected in many" 16 "dendritic cells: 55.5;granulocytes: 56.2;monocytes: 92.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.5;Karpas-707: 40.8;U-266/70: 57.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA062837 Enhanced NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 29: U-266 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "HPA062837: AB_2684877" "unprognostic (4.30e-3)" "unprognostic (1.45e-2)" "unprognostic (5.98e-2)" "prognostic favorable (2.84e-4)" "unprognostic (2.60e-2)" "prognostic favorable (4.89e-4)" "unprognostic (1.60e-2)" "unprognostic (1.42e-1)" "unprognostic (5.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (3.96e-2)" "prognostic unfavorable (2.65e-5)" "unprognostic (2.72e-1)" "unprognostic (1.51e-2)" "unprognostic (6.10e-2)" "unprognostic (3.61e-2)" 21.9 6.0 6.3 26.8 4.0 13.3 24.3 6.6 4.4 13.8 22.3 8.4 6.9 6.1 0.9 14.4 88.8 9.8 18.6 8.4 11.8 16.4 32.4 36.4 14.0 32.7 35.3 2.1 9.0 3.9 7.9 6.8 16.0 19.9 1.6 0.0 46.5 5.5 5.4 13.5 12.3 2.1 17.0 24.1 12.2 16.3 11.9 5.9 21.9 1.7 4.2 6.8 11.3 6.4 2.9 1.8 0.3 0.7 0.0 3.6 1.7 0.1 0.6 0.1 1.8 3.2 13.5 1.0 3.4 0.1 0.5 8.1 0.0 0.0 0.0 1.4 0.9 0.6 2.5 2.4 10.0 0.0 6.5 2.1 1.7 0.0 0.0 1.0 0.2 1.0 0.8 40.8 0.0 0.0 0.0 1.5 0.2 0.8 1.9 1.5 0.2 7.2 0.0 0.0 0.2 11.6 1.3 1.6 0.2 0.2 1.2 2.0 1.0 0.3 1.1 0.8 0.2 57.9 5.9 0.9 1.3 0.2 1.0 10.1 92.0 11.3 0.6 75.6 0.9 4.2 1.6 1.1 55.5 2.2 1.0 0.6 56.2 0.1 53.6 5.3 2.3 28.6 6.3 4.0 6.6 4.4 8.4 11.8 32.7 35.3 16.0 17.0 11.9 6.4 73.3 19.2 52.9 0.0 32.3 24.1 21.9 70.0 61.5 0.2 63.8 61.8 5.3 24.3 66.5 3.7 0.0 3.4 8.9 8.6 0.0 76.7 144.5 455.4 8.9 33.0 20.4 0.4 0.0 74.8 39.6 29.1 27.5 22.0 6.3 0.0 21.0 30.2 36.2 0.0 0.1 23.6 46.8 66.0 33.2 807.7 5.3 82.5 17.8 1.0 113.8 0.0 7.2 0.0 0.0 35.0 29.4 3.4 73.3 30.4 53.0 16.9 417.1 0.1 0.0 36.0 27.6 10.0 3.7 46.4 36.1 5.5 11.4 0.0 9.2 33.7 KLHDC7B MGC16635 ENSG00000130487 "Kelch domain containing 7B" Q96G42 22 50545899-50551023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.2;parathyroid gland: 13.7" "Cell type enhanced" "Detected in some" "B-cells: 5.2;Collecting duct cells: 5.5;granulocytes: 5.7;Kupffer cells: 5.2;monocytes: 21.1;NK-cells: 10.3;T-cells: 5.7" "Group enriched" "Detected in many" 4 "cervical cancer: 42.3;head and neck cancer: 11.4;urothelial cancer: 40.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HMC-1: 97.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000518, HPA076540" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA000518: AB_1079213, HPA076540: " "prognostic favorable (1.30e-4)" "unprognostic (3.18e-2)" "unprognostic (2.74e-2)" "unprognostic (2.21e-1)" "unprognostic (3.96e-2)" "unprognostic (6.04e-3)" "unprognostic (3.91e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (7.13e-2)" "unprognostic (3.33e-3)" "unprognostic (2.48e-1)" "unprognostic (2.09e-3)" "unprognostic (2.89e-1)" "unprognostic (4.69e-2)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" 0.2 0.2 0.2 2.1 0.1 1.0 0.3 0.1 0.2 0.5 0.1 0.3 0.4 0.2 0.3 0.4 0.1 0.3 0.0 0.1 0.2 3.7 0.4 0.7 2.3 0.5 0.2 0.0 0.1 13.7 1.0 0.1 0.3 0.4 0.1 0.0 1.3 0.2 0.0 0.3 1.1 0.1 0.2 2.7 0.5 0.2 0.4 5.2 2.0 0.0 1.3 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.8 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.2 97.7 0.1 1.2 0.0 0.2 0.1 0.0 0.0 0.0 11.6 0.0 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.3 0.0 0.1 1.1 1.1 0.1 2.0 1.9 1.4 1.9 2.1 2.6 0.9 1.3 2.3 2.0 0.2 0.7 1.4 0.3 2.0 1.5 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.2 0.3 0.2 0.4 0.2 0.0 0.0 0.6 0.0 5.2 0.1 0.0 1.6 0.0 0.0 3.0 1.4 0.5 0.0 1.6 5.5 0.0 0.0 2.5 0.1 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.7 0.1 0.2 0.5 0.3 5.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 5.2 1.2 0.0 0.0 2.7 0.0 0.0 21.1 0.0 10.3 0.0 0.0 1.3 0.0 0.0 2.8 0.1 0.0 0.3 1.6 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 SYCE3 C22orf41 ENSG00000217442 "Synaptonemal complex central element protein 3" A1L190 22 50551112-50562919 "Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 46 "testis: 142.1" "Cell type enhanced" "Detected in many" "Early spermatids: 497.2;Late spermatids: 99.0;Spermatocytes: 508.0;Spermatogonia: 182.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;Karpas-707: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA047813 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nucleoli, Golgi apparatus" "HPA047813: AB_2797234" "unprognostic (2.55e-1)" "unprognostic (2.52e-1)" "unprognostic (2.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.63e-1)" "unprognostic (1.73e-2)" "unprognostic (2.22e-1)" "unprognostic (2.98e-3)" "unprognostic (1.68e-2)" "unprognostic (4.05e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (2.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.55e-2)" "unprognostic (5.20e-2)" 0.4 1.1 1.7 0.5 1.7 0.3 1.1 1.7 3.0 0.4 1.5 0.7 0.2 0.0 1.6 0.5 1.2 1.0 0.3 1.7 1.8 2.8 1.8 0.6 0.5 1.9 2.0 0.0 0.4 0.6 1.3 0.3 2.1 0.4 0.1 1.3 0.5 0.1 0.1 0.5 0.2 0.0 1.6 0.2 0.4 142.1 1.8 0.8 1.7 0.0 0.3 0.5 0.2 1.8 0.2 0.4 0.1 0.1 0.3 0.3 0.2 0.3 0.0 0.1 0.0 0.0 5.0 0.2 1.7 0.0 1.0 0.0 0.5 0.5 0.0 0.0 0.2 0.0 0.4 0.0 2.1 0.0 0.9 1.3 1.1 0.2 0.8 0.2 0.0 1.0 0.0 4.1 0.2 1.8 0.0 0.0 0.2 2.1 0.0 0.0 0.0 2.3 0.6 1.5 0.4 1.3 0.0 1.2 0.9 0.2 1.2 1.0 0.0 0.4 0.4 0.0 0.0 1.0 0.2 0.7 0.5 0.1 0.1 0.0 0.7 0.8 0.0 0.6 0.1 0.0 0.0 0.0 1.1 0.2 0.0 0.1 4.3 0.0 0.5 0.0 0.0 0.1 1.7 1.7 1.7 3.0 1.7 1.8 1.9 2.0 2.1 1.6 1.8 1.8 0.3 0.0 0.0 0.0 0.1 0.1 0.4 3.7 2.8 0.8 5.6 5.6 0.5 2.8 2.1 1.8 0.0 5.9 0.1 0.4 3.9 1.7 497.2 2.7 0.4 0.7 0.0 0.0 0.1 0.6 3.2 0.2 0.0 2.0 0.0 0.0 0.7 3.2 1.7 0.0 0.1 0.1 4.1 1.2 0.0 99.0 10.8 0.8 0.0 0.0 2.9 1.2 0.0 0.0 0.2 0.9 0.1 7.2 0.0 0.6 0.4 7.6 4.7 0.8 46.0 0.0 0.7 508.0 182.4 0.8 0.1 3.7 0.1 0.0 0.2 0.8 CPT1B "CPT1-M, M-CPT1" ENSG00000205560 "Carnitine palmitoyltransferase 1B" Q92523 22 50568861-50578465 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 242.7;skeletal muscle: 144.5;testis: 80.7;tongue: 228.0" "Group enriched" "Detected in many" 4 "Early spermatids: 45.4;Late spermatids: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA079265 Enhanced NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "HPA079265: " "unprognostic (1.66e-1)" "unprognostic (2.99e-1)" "unprognostic (6.71e-3)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.18e-3)" "unprognostic (8.89e-2)" "unprognostic (7.16e-2)" "unprognostic (5.01e-2)" "unprognostic (9.50e-2)" "unprognostic (1.10e-3)" "unprognostic (9.76e-3)" "unprognostic (7.37e-2)" "unprognostic (4.98e-3)" "unprognostic (1.14e-1)" "unprognostic (8.43e-2)" "unprognostic (3.15e-5)" 10.3 9.3 13.8 11.4 15.5 13.4 15.7 17.4 17.4 7.7 12.2 14.0 13.5 4.6 10.3 16.6 7.3 6.1 242.7 13.6 14.7 25.1 25.6 10.5 14.4 16.7 14.6 5.0 18.3 34.1 23.5 8.1 15.8 15.7 10.6 17.1 13.1 3.4 144.5 14.1 22.2 3.6 13.6 27.5 13.0 80.7 16.1 9.8 26.7 228.0 13.1 9.9 10.3 17.8 8.2 7.7 24.5 9.0 5.3 3.1 17.5 0.3 3.1 4.1 4.5 3.6 7.2 16.3 2.2 2.0 6.0 13.6 12.9 2.9 3.6 6.5 14.2 8.0 26.2 3.9 1.4 8.5 22.3 1.8 22.0 2.9 4.8 15.0 0.7 11.4 2.9 27.8 3.9 11.9 2.9 16.3 5.2 4.3 4.9 15.2 7.8 3.5 10.3 19.6 6.6 12.7 5.7 9.7 10.9 14.8 10.8 17.9 1.6 11.4 11.4 7.4 2.8 22.3 5.5 8.7 4.9 15.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 13.8 15.5 17.4 17.4 13.6 14.7 16.7 14.6 15.8 13.6 16.1 17.8 0.5 0.0 11.0 0.0 0.8 0.3 0.0 1.0 1.8 1.9 2.2 1.0 3.7 1.5 1.5 3.7 2.1 0.5 0.2 5.6 0.0 2.2 45.4 0.9 0.1 1.0 0.0 0.0 0.0 2.1 0.6 1.4 5.6 0.4 7.0 0.1 0.4 2.1 0.6 3.3 0.0 5.2 0.0 0.6 0.8 109.3 0.3 1.0 1.8 0.0 6.3 0.4 0.0 0.0 0.0 1.0 6.4 0.7 0.4 0.0 3.5 0.5 3.7 2.0 0.0 0.9 0.3 16.3 2.4 1.0 0.3 0.4 1.2 0.0 4.2 0.1 CHKB "CHETK, CHKL" ENSG00000100288 "Choline kinase beta" Q9Y259 22 50578959-50601455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 19.1;RPMI-8226: 19.8" HPA018797 Approved Approved Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "HPA018797: AB_1846666" "unprognostic (6.03e-4)" "prognostic favorable (4.66e-4)" "unprognostic (4.31e-2)" "unprognostic (2.63e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (3.25e-3)" "unprognostic (1.70e-2)" "unprognostic (2.00e-1)" "unprognostic (7.84e-2)" "unprognostic (5.23e-3)" "unprognostic (5.43e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.33e-1)" "unprognostic (9.54e-2)" "unprognostic (1.30e-2)" "unprognostic (2.18e-3)" 14.1 13.0 10.3 0.7 10.3 12.1 13.4 10.5 16.8 10.6 12.2 10.5 3.3 9.5 12.0 11.1 12.0 1.5 11.5 10.1 10.8 13.2 9.4 13.3 4.3 10.5 11.0 8.6 7.7 17.7 14.3 7.2 10.6 12.0 4.8 1.6 11.9 7.2 8.3 11.6 10.7 5.3 10.7 18.1 11.6 14.5 11.0 9.2 12.6 11.7 9.8 11.7 11.1 10.8 4.2 1.3 0.5 1.6 6.7 5.9 10.8 7.3 16.7 4.7 3.1 1.4 2.1 2.1 4.2 3.8 2.4 0.0 1.5 2.0 1.0 0.3 5.4 3.1 2.2 2.3 19.1 2.5 4.8 2.0 6.5 0.6 8.1 4.5 17.1 5.5 1.8 0.3 12.4 5.3 2.0 8.6 0.7 7.0 1.9 3.5 1.8 19.8 11.5 2.0 2.0 3.2 3.0 7.3 5.9 0.2 1.1 2.8 6.9 0.0 1.7 0.0 2.2 7.4 0.0 3.0 2.3 0.4 3.4 12.0 39.5 27.0 26.4 38.4 25.7 24.0 24.2 27.6 35.7 23.6 22.6 20.8 9.6 37.0 26.1 34.1 33.4 32.6 10.3 10.3 10.5 16.8 10.1 10.8 10.5 11.0 10.6 10.7 11.0 10.8 16.7 6.4 28.2 0.0 13.6 4.8 2.3 6.9 8.6 4.8 10.0 7.4 7.7 20.0 12.7 7.3 4.2 8.8 14.0 18.4 3.9 30.6 11.6 3.9 3.4 8.0 15.7 9.0 0.0 23.8 14.1 8.6 19.9 3.3 19.0 2.5 10.4 5.4 14.6 8.4 0.0 19.3 12.2 16.6 9.2 30.5 2.5 10.0 3.6 0.0 48.4 3.3 14.4 0.0 0.0 23.5 24.2 3.0 14.6 2.1 29.3 5.5 11.2 6.0 6.6 2.4 6.8 12.6 10.0 14.5 6.3 8.5 11.2 2.8 17.3 2.2 MAPK8IP2 "IB2, JIP2, PRKM8IPL" ENSG00000008735 "Mitogen-activated protein kinase 8 interacting protein 2" Q13387 22 50600793-50613981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.0;pituitary gland: 35.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 57.8;Enteroendocrine cells: 32.3;Horizontal cells: 99.3;Rod photoreceptor cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 19.3;HEK 293: 11.0;SCLC-21H: 15.7;SH-SY5Y: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034780 Uncertain NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "HPA034780: AB_10670283" "unprognostic (7.82e-2)" "unprognostic (7.62e-2)" "unprognostic (3.48e-2)" "unprognostic (1.31e-2)" "unprognostic (5.80e-2)" "unprognostic (6.72e-2)" "unprognostic (1.18e-1)" "unprognostic (2.90e-1)" "unprognostic (5.23e-2)" "unprognostic (9.19e-2)" "unprognostic (8.57e-3)" "unprognostic (8.78e-3)" "unprognostic (6.33e-3)" "unprognostic (6.77e-2)" "unprognostic (1.72e-1)" "unprognostic (5.29e-2)" "unprognostic (4.75e-2)" 1.4 9.2 54.7 0.3 50.2 0.0 1.4 27.5 67.8 1.4 0.0 2.1 0.2 2.1 0.3 1.2 1.5 0.0 0.4 53.7 35.1 0.7 0.5 0.5 0.0 78.0 27.0 7.0 1.8 2.0 35.2 0.3 84.0 1.9 0.1 9.6 2.8 0.2 0.3 1.5 1.0 0.2 18.6 0.8 1.5 7.1 39.4 0.2 1.0 0.1 0.0 0.3 1.0 49.2 0.3 1.1 4.7 4.1 0.4 0.0 3.7 0.0 0.0 1.0 0.6 2.4 0.8 0.6 1.0 0.0 19.3 0.0 6.6 0.0 0.0 0.3 11.0 0.0 0.4 1.2 0.5 0.0 0.8 0.3 5.5 0.0 0.1 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 3.4 0.8 1.8 1.1 0.7 0.0 0.0 0.1 15.7 19.8 3.7 4.6 0.2 0.9 0.9 0.0 0.0 0.1 0.1 0.6 0.0 1.1 3.1 0.5 0.5 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.7 50.2 27.5 67.8 53.7 35.1 78.0 27.0 84.0 18.6 39.4 49.2 0.6 3.2 2.0 6.5 0.1 0.4 1.6 0.5 0.6 57.8 2.3 3.9 2.3 2.8 2.7 0.0 16.7 0.2 0.0 0.5 0.0 3.0 0.6 0.7 1.7 0.7 32.3 0.0 15.6 2.5 1.1 0.7 0.0 1.5 0.0 0.5 0.0 0.3 0.1 99.3 13.1 0.5 4.1 0.0 0.4 1.8 5.9 0.3 7.2 3.7 0.2 11.2 0.0 6.0 3.2 0.7 0.1 0.7 0.1 1.2 0.3 0.7 0.3 26.7 0.0 1.3 1.0 3.4 2.7 0.6 0.6 1.1 0.3 0.5 0.6 0.5 ARSA ENSG00000100299 "Arylsulfatase A" P15289 22 50622754-50628173 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Ichthyosis, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 127.5;Plasma cells: 132.0;Proximal enterocytes: 93.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005554, CAB025183" Enhanced Uncertain "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA 5600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" Cytosol "CAB025183: , HPA005554: AB_1078220" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (4.07e-2)" "prognostic favorable (2.96e-5)" "unprognostic (4.66e-2)" "unprognostic (4.40e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" "unprognostic (2.16e-1)" "unprognostic (4.47e-2)" "unprognostic (2.76e-1)" "unprognostic (9.90e-2)" "unprognostic (1.41e-2)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" "unprognostic (7.73e-3)" 28.8 25.1 14.4 15.6 18.0 18.4 27.2 16.8 21.8 21.3 27.5 31.3 30.8 22.4 8.6 28.1 25.1 15.7 33.0 14.9 15.2 31.4 42.8 29.1 19.8 20.0 15.9 11.3 46.7 11.7 34.7 10.9 19.1 28.9 8.2 4.4 39.6 16.2 25.3 17.5 33.8 6.5 16.3 44.5 30.3 54.0 19.4 9.8 32.3 5.1 9.5 23.9 24.7 21.0 8.5 11.0 5.3 10.9 41.8 21.8 13.5 13.0 15.9 5.7 9.3 3.3 12.9 5.3 8.2 22.9 10.8 12.8 1.2 12.3 1.0 2.7 8.0 3.4 14.3 12.5 28.3 5.2 32.7 26.0 24.4 9.5 6.3 19.9 12.8 11.5 3.5 80.4 12.1 9.6 4.6 5.8 1.7 9.0 11.2 4.0 0.4 26.7 9.9 13.5 2.5 8.2 18.2 17.2 10.1 5.1 7.7 6.6 22.1 3.8 15.1 14.9 4.1 18.4 1.9 4.5 11.7 4.3 13.6 10.4 27.7 36.1 17.3 33.3 15.1 10.4 12.4 14.2 22.7 12.5 7.3 10.0 60.4 8.9 43.2 32.1 18.2 16.3 14.4 18.0 16.8 21.8 14.9 15.2 20.0 15.9 19.1 16.3 19.4 21.0 22.8 6.4 12.9 24.5 22.2 4.7 14.0 23.8 18.8 5.3 18.9 13.1 8.0 27.1 15.5 12.9 4.2 11.5 14.0 85.4 1.9 29.4 62.4 24.4 10.3 13.4 36.7 9.7 9.4 21.3 19.9 19.6 41.3 21.3 6.3 15.3 8.2 28.6 36.8 6.7 8.6 30.6 14.2 29.0 9.5 127.5 10.8 29.2 17.8 10.3 28.7 10.3 8.2 8.0 11.9 24.2 75.2 6.0 132.0 10.8 93.9 22.7 21.2 7.2 0.0 6.6 9.9 48.3 4.1 18.3 5.5 13.3 17.2 7.2 25.0 16.1 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 ACR ENSG00000100312 Acrosin P10323 22 50738196-50745339 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "testis: 86.7" "Group enriched" "Detected in some" 33 "Early spermatids: 492.2;Late spermatids: 134.8;Spermatocytes: 216.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA048687 Enhanced "Secreted in male reproductive system" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA048687: AB_2680494" "unprognostic (1.71e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.27e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (3.30e-3)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "unprognostic (1.34e-2)" "unprognostic (2.12e-1)" "unprognostic (1.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (1.25e-1)" 2.6 0.2 0.4 0.0 0.5 0.0 2.0 0.4 0.5 0.8 2.6 0.5 0.1 1.1 0.7 0.4 1.1 0.2 1.0 0.4 0.3 0.9 0.8 2.0 0.0 0.3 0.3 0.3 0.2 0.0 0.5 0.1 0.5 0.6 0.0 0.1 0.6 0.2 0.8 0.8 0.5 0.2 0.4 3.0 0.3 86.7 0.4 0.0 0.6 0.0 0.0 0.6 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.4 0.5 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.4 8.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.3 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 492.2 0.4 0.1 4.7 3.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.5 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 134.8 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.8 2.6 0.0 0.0 1.2 0.4 0.0 0.0 6.6 0.3 0.1 216.9 2.5 0.3 0.0 0.0 0.0 0.1 1.5 0.2 RABL2B ENSG00000079974 "RAB, member of RAS oncogene family like 2B" Q9UNT1 22 50767501-50783662 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 99.4;Respiratory ciliated cells: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042642, HPA042700, HPA044007" Approved Approved Vesicles,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Centrosome Vesicles "HPA042642: , HPA042700: AB_2678120, HPA044007: AB_2678770" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (1.86e-3)" "prognostic favorable (5.58e-4)" "unprognostic (7.85e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (4.58e-5)" "unprognostic (3.14e-1)" "unprognostic (6.97e-2)" "unprognostic (7.33e-2)" "unprognostic (1.19e-2)" "unprognostic (7.51e-2)" "unprognostic (3.71e-3)" "unprognostic (7.43e-3)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (8.37e-3)" 13.2 12.9 18.1 18.6 18.8 14.4 15.8 18.1 22.4 23.9 73.6 16.5 12.5 21.7 90.3 13.3 66.6 14.5 10.2 23.3 17.0 17.7 12.2 21.8 23.1 23.3 33.2 22.5 16.3 14.6 26.7 11.6 17.9 16.2 16.7 30.2 16.8 16.9 8.8 22.2 15.6 15.6 21.9 19.3 14.5 23.1 20.1 21.6 28.2 4.6 20.3 17.0 15.7 18.5 23.0 20.4 34.1 26.7 37.3 29.6 25.0 16.7 18.5 13.2 18.1 5.8 19.7 14.7 14.7 24.1 21.6 29.5 15.8 19.6 14.2 13.3 23.2 12.8 40.2 15.1 15.4 36.1 13.0 25.3 26.2 17.5 21.9 39.2 15.0 26.0 9.9 17.9 26.7 28.8 18.2 15.9 13.2 14.0 15.0 30.1 19.8 16.1 25.9 22.4 14.6 26.5 20.5 17.8 13.4 23.4 17.7 11.2 23.2 12.6 25.1 10.9 11.4 15.2 7.4 7.2 23.8 8.8 18.1 1.8 14.4 13.1 21.4 23.5 15.5 15.2 16.4 17.3 15.7 19.2 18.7 18.3 5.4 15.9 28.4 18.0 18.6 14.7 18.1 18.8 18.1 22.4 23.3 17.0 23.3 33.2 17.9 21.9 20.1 18.5 6.2 12.8 13.4 14.4 16.8 5.4 13.4 13.3 15.9 15.2 13.3 11.8 5.1 12.8 24.1 22.0 31.3 12.1 16.2 10.6 13.7 21.3 25.7 99.4 11.2 7.2 5.4 9.9 25.7 10.8 11.1 11.4 9.7 8.6 3.8 22.1 5.3 8.9 12.0 16.8 18.9 8.0 22.4 10.1 6.9 24.2 14.0 8.4 17.8 4.7 14.4 13.9 36.0 7.1 15.1 10.4 4.9 10.9 8.0 7.3 8.6 16.3 188.6 40.0 6.6 15.0 14.8 38.8 27.0 8.8 5.7 6.7 16.0 11.9 10.7 6.5