Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" OR4F21 OR4F21P ENSG00000176269 "Olfactory receptor family 4 subfamily F member 21" O95013 8 166086-167024 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "BEWO: 1.0" HPA047705 Uncertain NA NA "Cluster 28: BEWO - Transcription regulation" "HPA047705: AB_2680125" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF596 ENSG00000172748 "Zinc finger protein 596" Q8TC21 8 232137-264703 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.1;Late spermatids: 20.4;Oligodendrocytes: 20.7;Spermatocytes: 63.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 11.4" "Low region specificity" "Detected in all" HPA055463 Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Mitochondria" "HPA055463: AB_2682821" "unprognostic (3.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.90e-1)" "unprognostic (9.07e-3)" "unprognostic (9.68e-3)" "unprognostic (2.10e-3)" "unprognostic (1.74e-1)" "unprognostic (4.84e-1)" "unprognostic (1.70e-5)" "unprognostic (6.37e-2)" "unprognostic (1.20e-1)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "unprognostic (3.51e-1)" "unprognostic (4.53e-1)" 2.6 3.5 4.2 2.0 4.5 1.8 5.2 8.3 5.0 3.8 4.6 2.7 2.7 7.1 7.0 2.3 4.1 2.1 3.4 4.0 5.5 4.2 3.0 3.1 3.8 4.4 4.1 5.0 3.4 4.9 4.6 3.6 4.3 3.9 3.2 18.7 2.3 4.0 2.9 4.5 2.6 3.2 3.2 5.0 3.7 15.5 5.1 3.4 5.7 1.8 2.8 2.7 2.5 6.8 1.6 1.1 4.5 11.4 2.1 2.3 3.6 3.6 1.5 1.3 2.4 1.1 2.0 1.6 1.3 2.7 1.9 3.3 1.2 2.6 1.7 1.2 1.9 3.3 3.3 1.3 2.4 1.4 1.8 4.8 0.4 1.5 2.4 2.2 1.0 5.7 2.4 5.4 7.8 5.6 4.0 1.8 2.4 3.0 1.1 1.6 1.0 2.7 4.4 2.7 2.7 6.7 2.3 1.2 1.8 2.3 3.6 4.1 2.6 3.3 0.9 0.3 1.8 1.7 5.1 2.2 4.1 1.4 2.4 4.6 1.5 2.3 2.4 1.2 3.1 3.2 2.5 2.2 1.7 3.6 2.9 3.4 1.4 1.5 2.9 2.3 2.9 1.3 4.2 4.5 8.3 5.0 4.0 5.5 4.4 4.1 4.3 3.2 5.1 6.8 2.3 3.2 2.7 10.1 2.2 0.4 0.7 2.6 2.2 8.3 1.3 1.8 2.9 1.5 2.4 1.8 2.1 2.1 0.8 1.6 3.9 2.1 60.1 1.5 2.7 2.5 0.0 1.7 14.1 1.7 1.4 2.1 5.1 1.3 5.1 2.9 2.2 0.9 1.1 11.8 15.7 1.5 4.1 0.8 0.3 20.4 4.1 0.9 0.0 9.4 0.5 5.4 1.0 15.6 20.7 1.3 0.5 1.2 2.9 0.7 1.6 1.9 3.8 9.0 0.0 2.6 1.8 63.7 4.5 3.1 0.4 1.5 1.8 2.9 1.5 0.5 FBXO25 FBX25 ENSG00000147364 "F-box protein 25" Q8TCJ0 8 406428-477967 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 97.8" "Cell type enhanced" "Detected in all" "Early spermatids: 625.7;Late spermatids: 312.5;Spermatocytes: 640.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 58.7;SK-MEL-30: 61.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (1.63e-1)" "prognostic favorable (5.38e-5)" "unprognostic (2.74e-2)" "unprognostic (5.11e-3)" "unprognostic (2.48e-1)" "unprognostic (1.25e-2)" "unprognostic (1.86e-1)" "unprognostic (9.23e-3)" "unprognostic (2.03e-2)" "unprognostic (1.55e-1)" "unprognostic (2.39e-3)" "unprognostic (3.30e-1)" "prognostic favorable (1.41e-4)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.11e-3)" "unprognostic (2.41e-1)" 14.4 20.4 9.3 7.6 9.4 9.1 13.8 13.4 11.8 9.1 8.3 16.6 15.4 8.4 16.8 10.0 8.6 9.3 15.3 8.8 9.2 15.8 30.0 10.4 12.0 8.8 10.2 8.8 28.6 14.2 12.1 6.8 9.1 24.9 18.7 7.2 16.3 10.5 18.3 12.4 11.1 11.0 8.4 8.1 15.1 97.8 8.6 20.7 18.6 19.7 12.1 11.3 9.0 11.4 13.4 10.6 4.5 8.8 6.9 4.4 18.6 12.6 18.5 11.8 18.1 6.0 12.7 0.3 3.4 19.4 17.8 8.5 8.7 24.5 16.1 10.0 14.5 7.1 6.3 28.3 20.5 11.4 13.7 12.7 37.6 3.6 18.7 17.9 5.0 58.7 8.4 0.1 13.9 12.8 50.8 13.6 2.1 29.0 4.6 2.4 3.4 18.1 15.4 22.5 13.7 14.4 12.7 4.2 61.5 11.2 9.0 8.1 7.5 4.8 4.1 0.8 10.1 9.2 14.4 13.6 13.0 4.7 14.7 1.6 9.1 6.6 9.0 10.8 11.1 16.2 10.7 8.5 9.1 10.9 9.5 9.4 0.7 9.9 9.9 9.0 12.5 6.9 9.3 9.4 13.4 11.8 8.8 9.2 8.8 10.2 9.1 8.4 8.6 11.4 21.3 19.2 28.5 15.3 24.2 34.8 19.6 28.0 19.9 31.8 35.9 21.7 36.6 42.9 20.4 35.0 10.4 20.0 26.8 30.4 72.4 53.3 625.7 20.0 17.8 25.7 43.3 12.6 20.5 102.6 18.9 18.2 16.3 27.4 20.3 15.4 28.2 77.0 25.4 53.8 20.0 58.2 42.7 32.7 24.2 312.5 38.8 17.4 39.2 11.2 36.2 22.1 38.1 8.5 28.3 51.5 41.2 29.3 21.4 39.1 34.9 58.3 13.2 36.3 26.3 17.8 16.2 640.9 142.1 17.4 40.5 16.1 19.5 14.4 47.2 21.8 TDRP "C8orf42, INM01, TDRP1, TDRP2" ENSG00000180190 "Testis development related protein" Q86YL5 8 489803-545781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.3;Early spermatids: 80.7;Syncytiotrophoblasts: 272.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 56.1;HBEC3-KT: 27.6;hTERT-RPE1: 23.7;SuSa: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008462 Approved Supported Vesicles,Cytosol NA NA 52000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Vesicles, Cytosol" "HPA008462: AB_1845777" "unprognostic (1.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.51e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (4.13e-2)" "unprognostic (1.08e-1)" "prognostic favorable (9.37e-4)" "unprognostic (1.74e-1)" "unprognostic (3.43e-2)" "unprognostic (5.46e-4)" "unprognostic (2.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.50e-1)" 8.7 10.4 12.4 2.2 13.6 0.2 8.7 12.8 14.4 13.3 23.0 6.8 2.1 10.0 9.8 3.9 18.5 10.7 4.6 12.5 14.7 26.9 15.9 9.8 4.4 14.2 13.5 19.5 8.9 16.1 16.7 36.4 13.2 14.7 2.6 16.9 6.5 8.6 1.7 3.3 4.9 5.1 12.4 4.0 6.1 14.0 15.5 4.8 24.6 2.6 5.1 9.9 7.7 10.8 9.9 9.8 16.7 0.0 0.0 0.0 56.1 5.6 3.5 5.3 4.6 0.0 0.0 0.0 2.3 1.8 5.3 2.1 0.0 27.6 6.6 0.0 0.7 0.1 0.0 14.8 6.4 0.0 4.1 6.4 21.4 0.0 10.0 23.7 0.8 0.1 1.2 0.0 5.7 0.0 0.1 0.1 20.0 0.0 2.1 0.0 0.0 0.0 17.0 14.5 5.0 8.1 0.0 17.2 4.5 27.4 5.7 0.0 0.3 0.3 1.7 0.0 0.5 0.0 0.0 0.0 1.7 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 13.6 12.8 14.4 12.5 14.7 14.2 13.5 13.2 12.4 15.5 10.8 20.4 22.4 15.4 41.8 1.0 23.5 28.6 7.3 39.3 17.8 15.8 10.8 4.4 12.8 10.5 18.4 2.1 151.3 0.4 0.5 43.0 10.2 80.7 19.5 10.7 21.2 7.8 0.0 33.3 4.8 61.2 12.2 0.5 7.3 0.0 9.7 7.9 21.0 12.7 10.1 39.9 1.6 16.2 1.9 5.8 16.1 7.2 7.4 8.8 53.4 0.2 9.2 0.0 16.6 4.5 2.9 1.0 6.4 2.5 34.3 0.0 20.7 28.4 12.4 19.7 9.0 10.5 21.5 11.0 7.1 7.0 272.1 0.9 1.7 0.7 14.7 ERICH1 ENSG00000104714 "Glutamate rich 1" Q86X53 8 614746-738106 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003725 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA003725: AB_1853023" "unprognostic (7.19e-2)" "unprognostic (1.38e-2)" "unprognostic (7.73e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-2)" "unprognostic (1.02e-1)" "unprognostic (7.51e-3)" "unprognostic (1.55e-1)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (1.36e-1)" "unprognostic (8.45e-2)" "unprognostic (5.11e-2)" "unprognostic (1.27e-1)" "unprognostic (8.63e-2)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" 15.9 8.7 7.3 17.2 6.5 23.0 13.7 6.4 8.2 10.7 8.3 11.0 8.4 10.1 6.6 10.4 10.5 9.1 10.7 6.9 7.1 22.5 11.6 14.6 21.1 9.0 7.1 11.6 9.0 7.9 11.5 10.1 8.4 9.1 7.2 5.1 9.8 5.8 10.8 13.0 12.4 7.9 6.0 15.3 10.5 8.0 8.4 11.8 13.2 5.5 10.7 12.7 11.6 7.1 15.8 22.2 11.7 14.0 12.4 15.0 24.3 14.9 7.9 13.3 14.6 14.4 9.9 36.0 6.9 12.5 25.3 26.0 21.7 22.9 9.4 15.7 28.1 25.1 15.1 20.8 13.9 15.5 22.6 17.4 14.5 10.1 13.0 13.7 14.7 31.2 26.3 20.2 13.5 13.2 30.0 27.5 18.6 17.6 9.9 27.0 7.6 25.0 14.9 28.7 5.4 15.0 10.9 13.8 20.2 19.2 5.8 18.4 23.7 9.7 4.6 0.6 16.2 13.1 36.7 38.9 19.9 24.6 10.5 24.7 33.0 12.5 8.4 32.3 7.5 17.9 9.7 8.4 17.1 20.1 8.1 7.1 30.0 12.3 29.8 12.7 7.5 10.4 7.3 6.5 6.4 8.2 6.9 7.1 9.0 7.1 8.4 6.0 8.4 7.1 71.0 44.8 36.1 17.9 75.3 36.6 47.0 47.9 32.5 23.3 32.6 32.5 23.0 27.1 31.2 33.1 12.5 62.0 55.4 49.2 109.5 38.4 16.1 35.9 52.2 65.8 19.7 43.9 24.4 36.6 60.4 40.7 66.8 57.4 41.1 48.3 62.4 31.9 41.9 48.8 21.0 50.4 32.6 70.9 68.0 9.2 60.3 69.9 35.6 23.4 126.9 18.2 78.2 11.1 22.5 55.4 54.3 40.6 34.6 51.5 33.3 58.9 26.9 22.1 39.5 33.6 35.6 48.5 58.4 23.2 40.9 54.0 68.3 27.0 39.8 37.0 DLGAP2 "C8orf68, DAP-2, ERICH1-AS1" ENSG00000198010 "DLG associated protein 2" Q9P1A6 8 737628-1708476 "Nuclear receptors, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;pituitary gland: 2.6;testis: 12.2" "Group enriched" "Detected in some" 8 "Excitatory neurons: 645.0;Inhibitory neurons: 467.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA030320 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA030320: AB_10600904" "unprognostic (8.86e-2)" "unprognostic (2.32e-1)" "unprognostic (5.32e-1)" "unprognostic (1.33e-1)" "unprognostic (5.42e-2)" "unprognostic (1.23e-3)" "unprognostic (1.07e-1)" "unprognostic (2.71e-2)" "unprognostic (5.01e-2)" "unprognostic (2.16e-2)" "unprognostic (1.90e-3)" "unprognostic (2.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.05e-3)" "unprognostic (1.96e-1)" "unprognostic (3.85e-1)" "unprognostic (3.81e-1)" 0.2 0.0 0.1 0.0 1.0 0.0 0.1 0.0 3.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 12.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 3.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 16.0 0.0 0.4 0.3 0.0 0.0 4.1 0.7 0.9 1.7 0.0 1.8 0.0 16.7 0.0 0.0 0.0 1.9 0.1 64.1 0.1 0.0 0.6 0.0 0.0 645.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 40.4 467.8 0.0 0.0 0.0 0.3 31.9 0.9 0.2 1.8 35.6 0.0 1.9 0.0 12.1 9.1 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.7 2.5 0.0 0.3 0.2 8.2 6.2 0.0 0.1 0.0 0.1 0.2 0.0 0.1 CLN8 "C8orf61, EPMR, FLJ39417, TLCD6" ENSG00000182372 "CLN8 transmembrane ER and ERGIC protein" Q9UBY8 8 1755778-1801711 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 136.8;Syncytiotrophoblasts: 131.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "plasmacytoid DC: 76.7" "Lineage enriched" "Detected in all" 5 "dendritic cells: 76.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "unprognostic (5.86e-2)" "unprognostic (1.95e-2)" "unprognostic (6.40e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-1)" "unprognostic (4.05e-3)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.66e-2)" "unprognostic (9.69e-3)" "unprognostic (1.83e-1)" "prognostic favorable (4.36e-8)" "unprognostic (1.36e-1)" "unprognostic (1.70e-1)" "unprognostic (6.24e-2)" "unprognostic (8.38e-2)" 5.4 5.2 11.4 3.7 15.7 9.1 4.3 14.6 12.4 4.7 6.6 4.9 5.0 3.2 11.2 9.8 3.3 7.5 6.2 10.6 11.3 6.2 8.9 8.9 6.5 18.2 15.2 2.5 10.1 8.0 3.5 6.0 18.5 3.8 4.4 3.8 5.1 3.6 5.9 13.2 6.3 4.0 16.9 7.9 6.8 5.9 15.1 3.2 5.1 3.3 7.2 4.4 5.8 24.3 3.6 8.5 6.2 6.5 8.3 8.4 14.8 8.3 5.1 4.2 5.2 8.6 10.0 4.4 2.3 8.2 5.6 13.7 4.9 15.6 8.6 3.3 3.6 4.4 3.2 4.9 4.7 3.7 19.1 8.4 12.2 5.8 4.1 10.1 9.2 3.2 6.0 2.6 13.1 9.0 6.0 3.2 6.1 14.0 7.3 4.2 4.3 3.4 7.8 15.4 3.2 3.9 3.5 8.1 4.6 12.7 16.2 4.2 17.3 11.3 3.2 0.9 5.2 1.5 5.4 5.0 11.4 7.3 16.9 7.4 10.6 4.7 6.4 13.6 7.1 10.3 6.9 4.5 10.6 14.0 6.7 4.4 3.7 5.1 12.5 76.7 8.0 6.4 11.4 15.7 14.6 12.4 10.6 11.3 18.2 15.2 18.5 16.9 15.1 24.3 18.3 9.6 17.5 6.2 30.1 54.7 71.6 38.6 26.7 27.6 23.4 13.2 7.7 20.0 37.2 31.3 31.3 38.0 115.3 28.5 15.6 27.2 5.4 20.5 6.9 34.7 19.7 40.8 7.4 19.0 18.0 32.7 13.7 37.2 27.3 17.1 27.8 28.5 44.1 40.4 7.6 17.5 50.8 54.6 136.8 5.9 8.1 69.8 21.4 8.4 22.3 13.9 23.7 10.1 27.1 19.3 20.7 12.0 9.1 76.5 19.5 10.6 27.1 26.1 13.1 22.5 16.8 34.4 23.5 20.1 63.5 131.6 22.0 16.1 15.4 61.2 ARHGEF10 "Gef10, KIAA0294" ENSG00000104728 "Rho guanine nucleotide exchange factor 10" O15013 8 1823926-1958641 "Disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 158.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024649 Approved Approved Nucleoplasm NA NA "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "HPA024649: AB_1845002" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-2)" "unprognostic (1.02e-1)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (7.27e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "unprognostic (2.43e-2)" "unprognostic (9.29e-2)" "unprognostic (3.37e-2)" "unprognostic (1.81e-2)" "unprognostic (4.42e-1)" "unprognostic (3.18e-2)" "unprognostic (4.46e-2)" 19.2 10.1 9.3 2.3 9.9 0.4 15.2 9.3 9.6 14.7 9.3 19.1 0.5 18.7 2.7 5.5 15.0 1.9 18.3 9.0 8.9 12.4 3.4 27.9 1.6 9.7 9.8 13.5 6.6 1.1 7.3 3.0 10.3 12.8 1.6 1.9 12.1 3.1 4.0 13.3 9.3 4.7 8.8 6.9 14.2 24.3 9.1 2.1 12.9 1.1 1.1 12.3 13.4 11.7 7.1 7.6 7.7 4.0 6.8 7.4 1.9 9.4 6.9 6.5 7.8 2.5 3.2 0.0 1.0 11.7 11.1 5.3 8.4 10.9 8.8 0.0 3.0 3.2 8.6 0.0 6.0 0.0 2.1 6.5 6.2 7.7 6.1 10.0 11.8 2.5 3.1 0.0 8.0 3.8 5.8 1.1 6.6 5.3 4.2 0.3 8.6 0.0 6.2 2.7 1.5 1.6 5.7 0.2 5.3 9.4 3.1 2.1 13.2 5.9 3.8 0.1 8.4 0.0 2.9 0.1 6.0 8.4 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.3 9.9 9.3 9.6 9.0 8.9 9.7 9.8 10.3 8.8 9.1 11.7 11.7 3.2 4.1 90.1 0.9 38.4 13.4 8.1 5.7 7.7 7.8 6.3 13.3 15.7 5.0 7.3 10.4 0.6 2.6 1.4 0.0 7.5 17.8 3.3 11.4 27.7 1.2 3.6 17.3 2.0 1.6 30.0 4.1 6.9 0.0 11.3 13.9 1.2 1.7 21.9 16.3 4.5 8.2 1.6 9.4 20.5 35.1 2.1 23.2 50.6 0.3 10.1 4.1 69.9 158.9 12.4 0.3 26.4 2.3 22.6 0.7 0.8 2.8 9.2 0.0 22.6 14.2 54.9 38.3 1.4 15.2 0.3 2.1 7.7 2.4 6.3 KBTBD11 "KIAA0711, KLHDC7C" ENSG00000176595 "Kelch repeat and BTB domain containing 11" O94819 8 1973677-2006936 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Proximal enterocytes: 58.0;Proximal tubular cells: 32.2" "Cancer enhanced" "Detected in many" "renal cancer: 14.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;HEK 293: 2.0;MOLT-4: 1.4;REH: 1.8;SCLC-21H: 2.0;SH-SY5Y: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051159 Uncertain Approved "Intermediate filaments" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 45: Enterocytes - Digestion" "Intermediate filaments" "HPA051159: AB_2681367" "unprognostic (1.19e-1)" "unprognostic (2.27e-1)" "unprognostic (1.20e-3)" "unprognostic (2.70e-2)" "unprognostic (2.03e-1)" "unprognostic (6.84e-2)" "unprognostic (2.76e-4)" "unprognostic (2.50e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (4.75e-2)" "unprognostic (9.53e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (1.04e-2)" 3.0 6.6 3.6 0.2 5.0 0.0 2.8 2.3 10.8 1.5 0.0 7.0 0.1 0.9 0.0 1.2 2.6 0.0 2.6 7.6 0.7 9.2 7.8 2.7 0.0 6.2 1.9 1.3 3.6 0.1 3.7 0.0 3.4 2.8 0.0 0.0 1.2 0.1 1.1 1.6 9.8 0.0 3.3 7.5 2.0 1.2 2.9 0.0 3.9 0.0 0.0 1.9 1.1 9.3 0.5 0.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 2.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 5.0 2.3 10.8 7.6 0.7 6.2 1.9 3.4 3.3 2.9 9.3 6.1 0.0 8.1 17.6 0.6 1.0 0.4 0.0 0.0 24.3 1.0 0.6 5.2 8.6 0.1 12.9 35.5 0.0 0.6 25.6 25.4 2.0 0.8 0.6 0.4 7.9 6.0 3.6 29.2 3.8 0.2 2.0 1.1 0.7 0.0 1.3 4.2 18.2 3.6 20.2 12.6 13.0 0.0 13.5 1.9 0.3 5.0 8.0 1.8 9.4 15.7 9.6 2.1 9.5 16.3 11.9 10.7 10.5 1.5 3.1 58.0 32.2 1.7 31.3 0.0 15.1 1.3 0.3 3.7 0.0 0.9 0.3 1.0 0.1 19.7 1.4 MYOM2 ENSG00000036448 "Myomesin 2" P54296 8 2045046-2165552 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 342.6;skeletal muscle: 387.9" "Group enriched" "Detected in many" 6 "Cardiomyocytes: 632.6;dendritic cells: 234.9;NK-cells: 268.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEK 293: 5.3;SCLC-21H: 2.2;U-266/84: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001765, HPA005953" Enhanced Approved Mitochondria NA NA 290000 "Cluster 38: Heart - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "HPA001765: AB_1079443, HPA005953: AB_1854258" "unprognostic (2.81e-2)" "unprognostic (1.11e-3)" "unprognostic (8.19e-2)" "unprognostic (1.35e-3)" "unprognostic (2.11e-1)" "unprognostic (1.86e-2)" "unprognostic (2.30e-5)" "unprognostic (1.10e-1)" "unprognostic (5.17e-2)" "unprognostic (1.34e-2)" "unprognostic (9.56e-2)" "unprognostic (2.54e-2)" "unprognostic (3.89e-2)" "unprognostic (2.71e-2)" "unprognostic (9.01e-2)" "unprognostic (3.22e-1)" "unprognostic (1.14e-1)" 0.1 0.2 0.3 0.1 1.1 0.2 6.1 1.8 1.6 0.2 0.0 0.6 0.2 0.3 0.7 1.2 0.3 0.1 342.6 1.0 0.0 2.7 0.4 0.7 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.3 0.0 3.7 0.1 0.4 1.9 0.6 387.9 0.8 0.4 0.4 0.0 2.2 0.3 0.4 0.1 0.0 0.1 62.4 0.0 0.4 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.1 1.8 1.6 1.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 3.7 6.4 3.0 11.8 1.6 3.6 2.7 2.0 1.2 3.2 2.7 5.1 632.6 20.0 1.0 3.7 0.0 0.0 234.9 1.8 13.7 4.6 15.2 2.7 1.8 5.6 0.0 3.6 21.8 1.7 0.1 26.7 0.5 1.9 5.7 1.5 4.6 6.8 1.4 6.7 2.8 2.1 2.0 2.7 5.1 8.3 0.6 4.8 3.6 3.7 3.0 7.3 268.8 1.5 2.0 2.5 0.8 1.5 11.1 1.2 1.2 26.0 5.3 4.8 0.0 11.6 13.9 55.9 21.4 1.3 2.8 0.1 22.3 1.5 1.2 1.4 CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.7" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4868.4;Inhibitory neurons: 3913.1;Oligodendrocyte precursor cells: 4521.8" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.9;U-2 OS: 2.2;U-266/70: 2.2;U-266/84: 2.1;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" 0.1 0.0 3.5 0.0 5.8 0.0 0.2 0.0 10.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 5.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 1.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.2 0.0 0.0 2.2 2.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 0.0 10.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.5 108.4 0.0 0.3 0.0 0.0 2.2 15.0 1.0 0.9 2.2 0.0 0.6 1.8 0.0 3.4 0.0 0.1 0.0 0.0 52.5 1.5 0.3 2.2 0.0 0.0 4868.4 0.0 1.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 3913.1 0.1 0.0 0.0 0.7 15.0 0.3 0.2 0.0 220.2 0.7 0.5 0.0 4521.8 135.2 0.0 0.1 0.4 0.0 0.0 0.0 1.2 9.7 0.6 0.0 0.2 0.5 10.2 5.3 1.0 0.1 3.6 0.1 2.8 0.0 0.1 MCPH1 "BRIT1, FLJ12847" ENSG00000147316 "Microcephalin 1" Q8NEM0 8 6406596-6648508 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 107.5;Inhibitory neurons: 94.3;Oligodendrocyte precursor cells: 78.4;Oligodendrocytes: 79.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008238, HPA012064, CAB012177" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "CAB012177: AB_303207, HPA008238: AB_1853655, HPA012064: " "unprognostic (1.00e-1)" "unprognostic (2.17e-2)" "prognostic favorable (8.52e-4)" "unprognostic (6.45e-2)" "unprognostic (1.16e-2)" "unprognostic (1.19e-2)" "unprognostic (1.14e-2)" "unprognostic (1.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (4.79e-2)" "unprognostic (5.55e-3)" "unprognostic (4.24e-2)" "unprognostic (2.48e-1)" "unprognostic (4.79e-2)" "unprognostic (2.94e-1)" 5.7 3.7 1.9 2.9 2.1 12.3 5.7 2.9 2.4 5.7 2.2 5.0 2.4 5.7 2.5 4.7 5.2 2.5 4.3 1.9 1.9 4.3 3.8 4.4 4.7 1.9 1.9 5.4 5.1 3.3 3.8 4.0 1.9 4.6 2.8 3.3 5.9 2.7 9.8 5.2 4.6 3.4 1.7 4.7 4.7 6.1 2.1 5.5 4.6 3.9 4.2 5.4 5.1 2.7 4.5 3.9 7.0 4.9 3.4 6.1 5.9 6.7 5.8 8.3 6.2 5.0 3.3 8.7 1.8 5.5 7.6 5.1 8.9 6.3 9.8 3.6 4.9 11.1 3.9 6.7 5.6 5.6 8.4 5.8 6.4 5.7 8.1 5.8 6.2 9.2 13.7 8.5 6.4 2.9 15.1 6.1 12.0 8.2 3.9 8.9 6.6 5.3 4.8 8.2 4.8 6.4 4.9 5.2 7.4 7.7 4.5 7.8 5.2 6.4 3.5 2.1 6.4 3.9 5.7 12.7 5.9 6.4 9.0 1.6 2.1 8.7 3.1 2.5 4.1 4.0 2.7 3.7 2.1 4.4 3.4 3.7 0.3 4.3 3.2 2.8 3.0 2.1 1.9 2.1 2.9 2.4 1.9 1.9 1.9 1.9 1.9 1.7 2.1 2.7 21.3 3.2 16.1 50.6 28.3 4.6 14.5 7.1 10.8 13.4 9.7 9.0 13.7 10.0 17.7 14.7 16.7 10.9 28.2 4.6 3.9 10.9 46.6 20.0 21.2 15.6 0.0 17.9 107.5 10.5 10.6 14.2 14.8 25.9 19.7 15.5 11.4 6.9 7.0 30.3 94.3 6.1 2.0 12.2 2.7 30.6 12.2 12.1 0.0 69.3 14.2 13.1 19.6 78.4 79.5 10.4 7.8 13.2 27.0 9.7 6.3 8.7 25.6 10.6 6.6 20.2 13.8 29.5 12.6 10.9 6.0 12.3 23.5 12.8 7.2 10.1 ANGPT2 Ang2 ENSG00000091879 "Angiopoietin 2" O15123 8 6499632-6563409 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 81.7;Endothelial cells: 182.2;Smooth muscle cells: 79.8" "Cancer enhanced" "Detected in all" "renal cancer: 12.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 8 "HMC-1: 17.9;HSkMC: 39.9;HUVEC TERT2: 62.6;WM-115: 22.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB011437, CAB017626" Approved "Secreted to blood" NA NA 3780000 110000 "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "CAB011437: , CAB017626: AB_1118956" "unprognostic (1.28e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (6.36e-5)" "unprognostic (1.66e-3)" "prognostic unfavorable (4.48e-4)" "unprognostic (2.94e-3)" "unprognostic (6.19e-3)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.52e-7)" "prognostic unfavorable (3.87e-4)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "unprognostic (6.44e-2)" 15.7 0.5 5.6 3.8 5.0 0.4 9.9 6.3 9.0 6.2 2.6 2.9 1.2 4.3 1.1 2.2 4.2 4.9 7.3 4.9 6.3 5.4 2.7 4.6 6.8 12.3 5.8 2.5 0.8 2.3 0.8 11.3 12.3 3.3 1.8 1.6 2.5 2.7 4.0 3.1 2.5 6.8 7.7 0.5 1.8 0.9 7.6 6.4 8.2 2.0 2.8 10.6 3.2 7.5 0.1 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.1 4.7 0.4 0.1 0.9 0.0 17.9 39.9 0.0 0.0 0.0 0.1 62.6 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.8 0.0 0.0 0.1 0.3 0.1 0.1 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.1 22.7 1.7 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.1 5.6 5.0 6.3 9.0 4.9 6.3 12.3 5.8 12.3 7.7 7.6 7.5 81.7 9.6 0.0 5.2 7.8 8.2 2.7 2.5 1.8 9.3 1.5 1.4 2.8 2.8 1.6 0.0 29.2 1.8 3.6 0.6 0.0 1.3 3.2 4.2 5.4 182.2 13.8 1.3 17.0 0.5 1.5 6.3 1.5 5.9 4.5 2.0 30.4 0.9 0.6 38.7 16.1 1.7 0.0 2.5 10.9 5.0 43.5 2.7 16.0 26.2 2.4 2.9 7.2 24.6 11.3 1.3 1.2 3.8 0.9 9.9 2.6 1.0 1.4 12.5 0.0 8.1 79.8 1.6 1.6 0.3 8.0 30.6 5.5 2.9 1.3 4.7 AGPAT5 "FLJ11210, LPAAT-e, LPAAT-epsilon" ENSG00000155189 "1-acylglycerol-3-phosphate O-acyltransferase 5" Q9NUQ2 8 6708642-6761503 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010644, HPA010950, HPA011646" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 43: Testis - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" Mitochondria "HPA010644: AB_1844647, HPA010950: AB_1844648, HPA011646: " "unprognostic (1.05e-3)" "unprognostic (4.69e-1)" "prognostic favorable (8.82e-4)" "unprognostic (2.05e-2)" "unprognostic (2.99e-1)" "unprognostic (1.44e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (4.92e-1)" "unprognostic (1.82e-1)" "unprognostic (2.98e-2)" "unprognostic (6.33e-2)" "unprognostic (2.91e-1)" "unprognostic (6.62e-2)" "unprognostic (2.83e-1)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (5.09e-3)" 5.4 11.8 6.7 2.9 6.8 2.3 4.9 7.2 8.3 6.5 6.1 8.0 3.1 6.6 7.9 8.5 7.4 1.8 3.4 6.6 7.4 7.2 10.0 4.5 4.1 7.8 7.4 5.8 6.4 3.3 10.3 4.1 7.6 6.0 4.2 5.2 5.0 5.6 11.3 3.5 6.7 2.9 7.6 4.8 6.9 22.5 7.1 4.7 4.0 2.7 3.7 4.7 5.8 8.7 8.5 7.0 15.3 6.8 3.4 5.2 9.4 4.3 4.6 7.9 7.0 4.6 7.3 21.8 3.2 3.3 10.8 11.0 9.5 9.5 11.2 4.6 6.6 27.4 7.0 10.5 9.1 12.4 10.0 7.6 10.0 6.7 9.8 8.2 13.6 9.5 19.9 10.7 11.4 6.3 23.5 20.1 20.4 13.6 5.8 15.0 15.0 8.2 7.9 13.1 24.4 14.8 4.1 7.9 9.4 8.1 3.6 20.5 5.5 10.8 5.4 4.4 12.4 4.0 12.8 11.3 7.3 13.8 12.9 1.8 1.9 1.2 0.7 2.4 1.6 4.4 1.3 1.4 1.2 5.1 0.9 1.1 0.2 2.7 2.2 4.4 1.2 1.4 6.7 6.8 7.2 8.3 6.6 7.4 7.8 7.4 7.6 7.6 7.1 8.7 15.7 3.2 4.4 58.8 46.5 9.1 18.8 14.2 19.4 7.8 14.2 10.5 5.8 11.5 9.0 7.3 2.1 9.4 23.5 17.4 3.9 11.2 40.0 30.0 27.9 22.3 22.1 50.0 45.0 10.0 14.2 10.4 27.0 83.6 18.9 10.6 10.4 41.9 12.2 6.7 46.8 10.1 14.2 16.0 4.6 34.7 15.8 12.6 7.2 33.7 7.5 42.3 6.2 56.8 60.2 10.2 16.0 15.4 22.3 30.4 9.8 22.5 14.6 9.8 6.6 14.0 24.7 26.2 10.9 30.9 10.4 18.5 17.4 15.0 25.2 11.9 XKR5 ENSG00000275591 "XK related 5" Q6UX68 8 6808517-6835524 "Predicted membrane proteins, Transporters" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.8;NTERA-2: 1.7;SCLC-21H: 1.3;SH-SY5Y: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "unprognostic (8.95e-2)" "unprognostic (1.72e-1)" "unprognostic (2.26e-1)" "unprognostic (2.46e-2)" "unprognostic (1.78e-1)" "unprognostic (6.73e-2)" "unprognostic (9.91e-2)" "unprognostic (2.16e-3)" "unprognostic (1.30e-1)" "unprognostic (7.91e-3)" "unprognostic (3.13e-2)" "unprognostic (9.19e-2)" "unprognostic (1.03e-2)" "unprognostic (1.76e-1)" "unprognostic (2.77e-2)" "unprognostic (4.06e-2)" 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.3 0.2 0.7 0.2 0.0 0.1 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.1 2.8 0.5 0.0 0.0 0.1 0.9 0.2 0.5 0.8 0.1 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.4 0.0 0.1 0.4 1.7 0.1 0.0 0.1 0.5 0.1 0.1 0.2 1.3 3.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 DEFB1 "BD1, DEFB-1, DEFB101, HBD-1, HBD1, MGC51822" ENSG00000164825 "Defensin beta 1" P60022 8 6870592-6877936 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 1746.1;pancreas: 747.8;salivary gland: 1975.0" "Cell type enriched" "Detected in many" 6 "Distal tubular cells: 13300.4" "Cancer enhanced" "Detected in many" "renal cancer: 522.9" "Group enriched" "Detected in many" 4 "amygdala: 1.2;cerebellum: 1.5;hypothalamus: 1.0;midbrain: 2.4;thalamus: 3.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 43.3" "Not detected" "Not detected" "Secreted in other tissues" NA NA 2500000 "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "unprognostic (2.31e-2)" "unprognostic (8.35e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (2.16e-3)" "unprognostic (4.41e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (5.94e-4)" "unprognostic (3.24e-1)" "prognostic favorable (1.90e-5)" "unprognostic (9.62e-2)" "unprognostic (2.86e-2)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" 11.1 0.7 1.2 1.5 0.0 5.3 41.5 1.5 0.4 305.4 0.3 20.7 5.1 6.2 16.4 190.6 21.2 54.9 1.3 0.0 1.0 1746.1 248.4 5.7 0.0 0.0 2.4 0.5 747.8 6.9 12.7 2.1 0.2 37.9 11.5 1.9 1975.0 24.5 2.9 217.6 8.7 0.3 0.0 0.3 33.3 0.4 3.0 3.0 3.6 0.0 9.0 11.6 152.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.2 0.0 0.5 0.0 2.2 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 4.2 0.0 0.1 0.3 0.0 2.7 1.2 43.3 0.3 1.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.5 0.4 0.0 1.0 0.0 2.4 0.2 0.0 3.0 0.2 0.7 3.2 4.5 0.0 6.8 90.1 641.5 210.5 134.9 0.4 46.9 26.9 0.1 1976.0 57.2 982.1 0.0 11.8 0.4 117.6 13300.4 1860.0 0.0 339.5 223.6 8.8 15.7 0.0 0.0 295.4 0.9 19.0 1.5 1529.3 0.0 0.0 3.3 319.3 3.6 0.0 0.0 8.6 46.8 4.4 7.3 0.1 17.4 17.0 7.2 0.0 15.3 0.6 0.0 0.0 0.0 156.9 91.2 0.0 1.2 537.6 59.1 218.9 9.5 0.7 0.0 1.4 14.3 0.0 0.0 237.0 537.6 3.7 13.8 0.0 15.4 257.0 DEFA6 "DEF6, HD-6" ENSG00000164822 "Defensin alpha 6" Q01524 8 6924697-6926076 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 863 "intestine: 4819.9" "Group enriched" "Detected in some" 6 "Proximal enterocytes: 448.9;Undifferentiated cells: 904.1" "Group enriched" "Detected in many" 5 "cervical cancer: 21.2;colorectal cancer: 75.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "BEWO: 14.7;NB-4: 15.9;RPMI-8226: 19.7;SH-SY5Y: 12.2;U-2197: 5.7" HPA019462 Enhanced "Secreted to digestive system" NA NA 260000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA019462: AB_1847595" "unprognostic (7.48e-3)" "unprognostic (1.63e-1)" "unprognostic (1.34e-1)" 0.1 0.2 0.0 5.5 0.0 0.3 0.2 0.0 0.0 0.0 0.0 25.7 2862.9 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.2 3.4 0.0 0.0 0.2 0.4 0.0 0.5 0.0 0.1 0.3 3.3 0.0 0.3 0.0 0.2 0.6 4819.9 0.0 0.0 0.2 0.4 0.6 0.0 2.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.0 0.0 19.7 0.0 0.0 1.1 12.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.5 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.4 0.0 0.0 0.0 448.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 904.1 0.0 DEFA4 "DEF4, HP-4" ENSG00000164821 "Defensin alpha 4" P12838 8 6935820-6938306 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 58 "bone marrow: 2702.9" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Hepatocytes: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "neutrophil: 13.1" "Lineage enriched" "Detected in many" 13 "granulocytes: 13.1" "Cell line enriched" "Detected in single" 8 "THP-1: 6.8" HPA051266 Enhanced "Secreted to blood" NA NA 98000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "HPA051266: AB_2681414" 0.7 0.1 0.0 0.2 0.0 2702.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.3 2.7 14.2 0.6 0.0 0.0 0.0 0.1 0.0 0.7 1.1 0.0 0.0 0.0 0.0 2.3 0.0 0.4 2.0 0.1 0.0 0.0 46.4 0.1 0.1 0.0 8.9 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 DEFA1 "DEF1, DEFA2, HNP-1, MRS" ENSG00000206047 "Defensin alpha 1" P59665 8 6977649-6980080 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 18020.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.1" "CAB032548, HPA052517" Enhanced "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "CAB032548: AB_2277258, HPA052517: AB_2681860" 31.6 4.3 0.7 0.6 0.8 18020.9 16.8 0.5 3.0 4.0 0.6 4.1 0.0 11.3 0.0 3.2 2.2 1.3 62.5 0.5 0.6 15.0 91.6 560.5 3.5 0.7 0.7 4.1 5.5 0.1 20.6 11.4 0.7 2.7 0.0 0.3 14.5 0.0 16.8 40.3 2.3 0.0 0.8 1803.8 6.4 3.1 0.8 37.0 15.8 0.0 0.8 3.4 5.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 3.0 0.5 0.6 0.7 0.7 0.7 0.8 0.8 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DEFA1B ENSG00000240247 "Defensin alpha 1B" P59665 8 6996766-6999195 "Cancer-related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 872.0" "Cell type enriched" "Detected in single" 37 "T-cells: 3.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052517 Supported "Secreted to blood" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: Alveolar cells - Smell perception" "HPA052517: AB_2681860" 2.3 0.3 0.1 0.8 0.1 872.0 1.1 0.1 2.0 0.0 0.1 0.2 0.0 0.9 0.0 0.1 0.1 0.0 3.8 0.2 0.1 0.9 9.1 52.1 0.0 0.2 0.1 0.3 0.1 0.0 1.4 7.2 0.4 0.1 0.0 0.1 9.4 0.0 0.8 0.2 0.2 0.0 0.1 150.4 0.6 0.1 0.4 27.8 1.2 5.8 1.4 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 0.2 0.1 0.2 0.1 0.4 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 DEFA3 "DEF3, HNP-3" ENSG00000239839 "Defensin alpha 3" P59666 8 7015869-7018297 "Cancer-related genes, Predicted secreted proteins" "Antiviral defense" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 64 "bone marrow: 37615.2" "Cell type enhanced" "Detected in some" "B-cells: 17.9;Erythroid cells: 10.1;Hepatocytes: 17.0;Macrophages: 5.7;Plasma cells: 4.0;T-cells: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 19 "neutrophil: 854.3" "Lineage enriched" "Detected in many" 19 "granulocytes: 854.3" "Cell line enriched" "Detected in single" 8 "NB-4: 1.5" HPA052517 Supported "Secreted to blood" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "HPA052517: AB_2681860" "unprognostic (8.21e-2)" 8.8 1.2 0.5 1.0 0.3 37615.2 5.0 0.2 1.2 2.0 0.3 1.3 0.0 5.6 0.0 1.0 0.7 0.2 16.1 0.2 0.3 4.4 26.1 180.2 5.3 0.4 0.6 1.3 1.6 0.0 7.6 18.8 0.5 0.8 0.0 0.2 24.2 0.0 5.0 42.1 0.7 0.0 0.5 589.4 1.8 0.6 0.6 147.9 4.5 1.1 1.3 1.1 1.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 24.4 3.6 44.3 1.2 1.6 2.3 1.0 0.8 1.0 1.1 6.9 0.3 854.3 0.4 2.6 1.4 0.3 6033.6 0.5 0.3 0.2 1.2 0.2 0.3 0.4 0.6 0.5 0.5 0.6 0.2 0.0 0.0 0.0 0.0 17.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.8 17.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 5.7 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 1740.2;Undifferentiated cells: 1753.0" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 28.3;NB-4: 24.2;RPMI-8226: 26.6;SH-SY5Y: 19.6;U-2197: 8.5" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" 0.3 0.4 0.1 12.7 0.1 0.2 0.5 0.1 0.5 0.0 0.1 56.6 5185.1 3.9 0.1 0.8 0.0 0.0 0.4 0.1 0.2 0.2 1.1 0.4 6.0 0.1 0.2 0.4 0.8 0.0 1.1 0.0 0.2 0.7 0.2 0.1 0.7 0.0 0.3 0.3 9759.8 0.1 0.1 0.4 0.9 0.8 0.2 0.4 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 2.5 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.5 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 325.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 399.9 0.0 0.0 0.0 1740.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 1753.0 0.0 USP17L1 USP17L1P ENSG00000230549 "Ubiquitin specific peptidase 17 like family member 1" Q7RTZ2 8 7332387-7333979 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.2 0.2 0.7 0.2 0.3 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L4 ENSG00000236125 "Ubiquitin specific peptidase 17 like family member 4" A6NCW7 8 7337115-7338707 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF705G ENSG00000215372 "Zinc finger protein 705G" A8MUZ8 8 7355517-7385558 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Early spermatids: 28.8;Late spermatids: 30.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 34: Spermatids - Unknown function" "unprognostic (1.71e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 28.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB4B DEFB4P ENSG00000177257 "Defensin beta 4B" O15263 8 7414855-7416863 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 12.0;lymphoid tissue: 3.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (1.35e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB103B ENSG00000177243 "Defensin beta 103B" P81534 8 7428888-7430348 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "cervix: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11B "EDDM2B, EP2, EP2C, EP2D, HE2" ENSG00000164871 "Sperm associated antigen 11B" Q08648 8 7442684-7463674 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1636 "epididymis: 864.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 864.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DEFB104B ENSG00000177023 "Defensin beta 104B" Q8WTQ1 8 7470308-7475082 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106B ENSG00000187082 "Defensin beta 106B" Q8N104 8 7482504-7486400 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 685 "epididymis: 68.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105B ENSG00000186599 "Defensin beta 105B" Q8NG35 8 7487679-7489593 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12966 "epididymis: 2383.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "NB-4: 4.2" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2383.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107B HsT21816 ENSG00000198129 "Defensin beta 107B" Q8IZN7 8 7495911-7509311 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5377 "epididymis: 537.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 537.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR23D1 ENSG00000255251 "Proline rich 23 domain containing 1" E9PI22 8 7539628-7542450 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "epididymis: 46.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A7P FAM90A7 ENSG00000285975 "Family with sequence similarity 90 member A7, pseudogene" A6NKC0 8 7556700-7559712 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Uncertain Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A22P FAM90A22 ENSG00000285687 "Family with sequence similarity 90 member A22, pseudogene" A8MWA6 8 7571995-7575006 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A23P FAM90A23 ENSG00000285765 "Family with sequence similarity 90 member A23, pseudogene" A8MXZ1 8 7579644-7582653 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A14P FAM90A14 ENSG00000285814 "Family with sequence similarity 90 member A14, pseudogene" P0C7W9 8 7715443-7718453 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A18P FAM90A18 ENSG00000285913 "Family with sequence similarity 90 member A18, pseudogene" A6NE21 8 7723091-7726101 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A16P FAM90A16 ENSG00000285620 "Family with sequence similarity 90 member A16, pseudogene" A6NEW6 8 7730739-7733749 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A8P FAM90A8 ENSG00000285937 "Family with sequence similarity 90 member A8, pseudogene" A6NJQ4 8 7738387-7741396 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Uncertain Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A17P FAM90A17 ENSG00000285720 "Family with sequence similarity 90 member A17, pseudogene" A6NEW6 8 7746034-7749044 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A19P FAM90A19 ENSG00000285657 "Family with sequence similarity 90 member A19, pseudogene" A6NE21 8 7753682-7756692 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A9P FAM90A9 ENSG00000285607 "Family with sequence similarity 90 member A9, pseudogene" A6NNJ1 8 7761330-7764340 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Uncertain Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM90A10P FAM90A10 ENSG00000285950 "Family with sequence similarity 90 member A10, pseudogene" A6NDY2 8 7768977-7771988 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA060078 Approved Nucleoplasm,Nucleoli NA NA Nucleoplasm Nucleoli "HPA060078: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR23D2 ENSG00000255378 "Proline rich 23 domain containing 2" P0DMB1 8 7778591-7781413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "epididymis: 46.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB107A "DEFB-7, DEFB107" ENSG00000186572 "Defensin beta 107A" Q8IZN7 8 7811720-7815716 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 1392 "epididymis: 139.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045626 Approved "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045626: AB_2679396" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB105A "DEFB-5, DEFB105" ENSG00000186562 "Defensin beta 105A" Q8NG35 8 7821966-7823889 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB106A "DEFB-6, DEFB106" ENSG00000186579 "Defensin beta 106A" Q8N104 8 7825139-7829053 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16935 "epididymis: 3003.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 18 "NB-4: 2.2" HPA045592 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "HPA045592: AB_2679378" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3003.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB104A "DEFB-4, DEFB104, DEFB4" ENSG00000176782 "Defensin beta 104A" Q8WTQ1 8 7836436-7841242 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 763 "epididymis: 1308.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045292 Supported "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "HPA045292: AB_2679288" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1308.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPAG11A "EDDM2A, HE2" ENSG00000178287 "Sperm associated antigen 11A" Q6PDA7 8 7847876-7868867 "Predicted intracellular proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 11461 "epididymis: 4564.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;NB-4: 5.7;RPMI-8226: 1.7" "HPA023842, HPA057479" Supported Approved "Golgi apparatus" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" "HPA023842: AB_2732429, HPA057479: " 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4564.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB103A "DEFB-3, DEFB103, DEFB3, HBD-3, HBD3, HBP-3, HBP3" ENSG00000176797 "Defensin beta 103A" P81534 8 7881392-7882663 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.6;salivary gland: 3.2;vagina: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 5.8;LHCN-M2: 1.7;U-2197: 3.0" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 2.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 7.6 0.0 3.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB4A "DEFB-2, DEFB102, DEFB2, DEFB4, HBD-2, SAP1" ENSG00000171711 "Defensin beta 4A" O15263 8 7894677-7896716 "Predicted secreted proteins, Transporters" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 124.1" "Group enriched" "Detected in some" 8 "Basal respiratory cells: 79.5;Club cells: 38.3;Exocrine glandular cells: 37.4;Pancreatic endocrine cells: 41.0" "Group enriched" "Detected in many" 6 "head and neck cancer: 32.2;melanoma: 9.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "EFO-21: 1.4" "Secreted in other tissues" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "unprognostic (6.96e-2)" "unprognostic (1.17e-2)" "unprognostic (2.72e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 124.1 0.1 3.6 0.0 0.0 0.0 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.0 0.0 3.2 0.4 0.0 0.0 0.0 7.3 0.0 0.0 5.0 0.0 0.0 7.6 0.2 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.5 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.1 0.0 5.6 0.0 4.3 0.0 5.3 0.2 0.0 0.0 0.0 0.0 37.4 0.0 0.0 3.1 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.0 1.1 0.0 0.0 0.1 0.0 0.1 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 ZNF705B ENSG00000215356 "Zinc finger protein 705B" P0CI00 8 7926337-7952413 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 10 "testis: 1.0" "Group enriched" "Detected in some" 6 "Early spermatids: 3.6;Late spermatids: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L8 ENSG00000237038 "Ubiquitin specific peptidase 17 like family member 8" P0C7I0 8 7971661-7973253 "Enzymes, Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L3 "USP17B, USP17F" ENSG00000225327 "Ubiquitin specific peptidase 17 like family member 3" A6NCW0 8 7976393-7977985 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRAG1 "DKFZp761P0423, NACK, PEAK2, PRAGMIN, SgK223" ENSG00000275342 "PEAK1 related, kinase-activating pseudokinase 1" Q86YV5 8 8317736-8386439 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;thyroid gland: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 45.9;Breast glandular cells: 14.1;Breast myoepithelial cells: 11.0;Hofbauer cells: 18.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 35.0" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 50.2;NTERA-2: 32.1;SuSa: 32.1" "Low region specificity" "Detected in all" "HPA011776, HPA012066" Uncertain Uncertain "Nucleoli,Focal adhesion sites" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 7: Non-specific - Mitochondria" Nucleoli "Focal adhesion sites" "HPA011776: , HPA012066: AB_1847706" "unprognostic (7.04e-3)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" "unprognostic (2.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.92e-1)" "unprognostic (1.05e-1)" "unprognostic (4.78e-3)" "unprognostic (2.64e-3)" "unprognostic (5.19e-2)" "unprognostic (4.95e-2)" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (5.27e-2)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (5.22e-3)" 8.7 1.0 9.2 5.2 12.0 0.6 9.4 35.0 5.8 2.8 0.0 5.3 11.3 1.7 0.2 5.5 5.6 2.3 6.1 5.3 1.4 3.7 2.7 5.2 8.1 1.2 3.0 3.8 3.3 2.2 1.5 5.7 1.8 2.5 4.1 0.2 5.0 1.5 7.4 7.5 11.6 1.4 0.1 8.4 4.8 2.2 4.6 3.0 23.2 3.4 6.1 2.3 2.8 1.8 6.2 50.2 5.6 0.7 0.0 0.3 14.1 12.8 2.7 4.9 2.0 25.0 14.4 10.2 8.6 6.1 13.5 21.9 1.0 15.3 1.0 0.5 1.6 0.0 6.2 14.2 5.3 1.5 15.4 1.2 9.8 0.8 2.2 2.9 10.2 1.5 0.0 0.1 3.8 8.5 1.4 4.8 32.1 19.5 12.9 6.6 6.0 2.5 7.2 17.5 2.8 1.9 4.9 13.9 5.0 32.1 10.8 6.3 13.7 0.5 12.9 0.0 3.2 0.8 1.1 13.9 3.1 3.4 7.4 0.0 0.2 0.9 0.4 0.0 0.3 1.2 0.6 0.2 0.3 0.9 1.6 1.3 0.0 0.5 0.8 1.9 0.0 0.2 9.2 12.0 35.0 5.8 5.3 1.4 1.2 3.0 1.8 0.1 4.6 1.8 45.9 9.6 6.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 7.5 5.3 0.0 0.0 9.0 0.0 3.0 1.4 5.6 0.0 0.0 0.0 3.1 7.2 2.5 0.0 1.7 2.5 1.7 0.0 0.0 18.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.9 0.0 0.0 2.7 1.5 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.8 2.3 7.4 0.0 0.0 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 MFHAS1 "LRRC65, MASL1, ROCO4" ENSG00000147324 "Malignant fibrous histiocytoma amplified sequence 1" Q9Y4C4 8 8783354-8893630 "Disease related genes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Signal transduction inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 105.4;Glandular and luminal cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "MOLT-4: 128.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051213, HPA054471" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA051213: AB_2681391, HPA054471: AB_2682498" "unprognostic (1.33e-1)" "unprognostic (4.46e-3)" "unprognostic (1.22e-3)" "unprognostic (3.60e-1)" "unprognostic (1.95e-1)" "unprognostic (8.91e-3)" "unprognostic (2.70e-2)" "unprognostic (2.68e-3)" "unprognostic (9.23e-3)" "unprognostic (7.18e-2)" "unprognostic (1.83e-1)" "unprognostic (1.81e-1)" "unprognostic (2.01e-3)" "unprognostic (5.93e-2)" "unprognostic (4.91e-1)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" 5.8 2.0 7.3 7.9 6.9 11.9 3.6 7.5 8.7 6.3 4.1 12.8 6.1 5.1 3.3 5.3 6.6 5.5 6.6 8.3 6.4 13.5 6.0 9.9 10.4 6.1 7.4 3.4 4.6 5.7 2.0 8.8 6.5 5.3 11.4 5.4 3.4 4.4 2.4 6.1 7.0 8.2 6.5 11.1 6.3 6.0 9.0 9.0 5.4 2.7 8.6 9.2 3.5 6.2 19.5 14.4 8.6 6.6 8.0 10.1 28.3 7.9 17.0 5.6 7.6 23.3 3.7 28.5 9.5 7.6 16.2 6.5 9.1 7.3 4.9 37.0 8.1 2.1 5.3 15.1 9.5 8.2 2.9 5.5 15.0 7.6 7.5 6.0 12.5 34.8 13.4 0.0 4.7 7.0 128.0 7.2 16.8 25.8 6.1 17.4 13.1 4.4 39.3 20.0 13.6 11.0 4.6 7.2 12.7 14.6 4.9 11.1 5.3 6.8 10.1 27.3 15.4 1.5 6.9 21.7 12.6 10.8 4.2 0.0 0.1 0.0 0.9 0.0 0.7 0.4 1.3 0.8 0.2 0.3 0.6 0.5 0.0 0.1 0.0 0.0 1.2 0.3 7.3 6.9 7.5 8.7 8.3 6.4 6.1 7.4 6.5 6.5 9.0 6.2 10.7 54.5 43.9 105.4 6.5 37.5 24.5 6.0 2.8 19.0 6.2 3.2 17.2 20.0 16.5 31.3 4.2 3.7 6.5 30.9 13.7 12.0 2.5 50.8 20.3 19.2 18.8 71.4 46.9 15.4 3.2 17.8 8.2 119.2 22.2 5.4 25.4 17.8 31.8 3.3 56.8 29.3 10.2 27.5 21.0 3.4 11.5 13.0 10.6 61.8 8.0 24.3 14.4 38.2 6.2 28.5 20.7 8.2 2.1 47.5 6.7 16.5 5.4 8.1 0.0 4.5 24.1 1.9 21.7 2.4 50.0 2.3 24.0 1.7 36.3 16.9 ERI1 "3'HEXO, THEX1" ENSG00000104626 "Exoribonuclease 1" Q8IV48 8 9002147-9116746 "Predicted intracellular proteins" "RNA-mediated gene silencing, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033838, HPA055548, HPA056074" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules Vesicles "CAB033838: AB_2098575, HPA055548: AB_2682845, HPA056074: AB_2683029" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "prognostic favorable (8.05e-5)" "unprognostic (1.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.61e-3)" "unprognostic (1.08e-3)" "unprognostic (2.90e-1)" "unprognostic (5.50e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-3)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.27e-2)" "unprognostic (3.57e-1)" "unprognostic (8.75e-2)" "unprognostic (2.36e-2)" 5.3 3.1 3.1 6.5 3.8 13.0 4.8 3.7 4.1 4.3 3.5 3.8 4.7 4.7 2.5 4.3 3.9 3.9 2.8 3.0 3.5 4.2 4.4 5.1 7.4 4.5 3.9 4.2 3.0 4.2 2.5 6.7 3.7 3.2 4.6 11.3 3.8 3.2 2.4 3.2 3.8 5.1 3.8 5.0 3.6 9.1 3.8 6.9 2.9 2.7 7.4 6.2 3.5 4.1 32.3 19.9 17.2 13.1 13.4 21.7 23.5 27.4 14.4 19.6 24.1 14.8 14.4 36.7 7.0 15.7 32.7 11.2 15.1 18.5 27.3 15.1 10.8 20.3 15.8 11.5 13.7 15.6 28.6 12.9 6.1 16.3 14.4 10.9 26.8 21.6 23.3 22.6 22.8 10.5 47.2 19.3 20.0 24.2 12.1 20.1 25.1 13.7 25.2 45.6 2.4 18.8 16.4 12.5 13.8 12.1 9.3 13.9 23.2 20.7 21.4 39.5 21.6 4.9 18.1 31.9 15.3 22.2 16.5 6.4 4.6 3.4 4.2 5.1 4.3 5.3 4.9 4.4 3.9 3.9 3.8 3.6 3.3 6.0 3.5 2.9 9.8 3.5 3.1 3.8 3.7 4.1 3.0 3.5 4.5 3.9 3.7 3.8 3.8 4.1 9.2 3.2 8.1 17.6 9.7 18.2 9.6 6.7 3.4 17.4 8.6 5.0 5.7 2.8 10.1 3.7 14.6 25.3 11.3 7.4 3.9 9.0 46.9 14.8 14.4 8.6 3.6 18.7 11.4 12.0 27.6 9.1 8.6 23.3 8.2 7.7 11.4 4.8 13.5 5.0 9.7 5.2 8.2 9.7 15.9 16.7 6.5 12.9 10.6 9.4 11.9 8.0 6.2 9.5 16.7 11.2 5.6 9.1 11.2 6.3 4.3 8.2 9.1 21.6 13.1 7.8 7.5 43.6 45.6 6.1 10.1 20.8 11.7 5.9 6.8 3.8 PPP1R3B "FLJ14005, GL, PPP1R4" ENSG00000173281 "Protein phosphatase 1 regulatory subunit 3B" Q86XI6 8 9136255-9151574 "Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.9;skeletal muscle: 95.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 69.9;Hepatocytes: 184.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 53.6;eosinophil: 15.8;neutrophil: 50.4" "Lineage enriched" "Detected in all" 19 "granulocytes: 53.6" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 47.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA028731 Enhanced Approved Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "HPA028731: AB_10602120" "unprognostic (4.97e-3)" "unprognostic (1.45e-2)" "unprognostic (2.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.39e-1)" "unprognostic (5.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (4.98e-2)" "prognostic unfavorable (4.08e-7)" "prognostic unfavorable (6.03e-5)" "unprognostic (3.33e-1)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" 24.1 7.5 1.9 8.2 2.8 12.3 15.9 3.4 3.8 19.6 5.9 16.1 4.6 19.8 4.4 17.2 12.9 9.0 29.9 1.7 3.1 7.6 144.9 9.2 4.3 4.8 3.0 10.4 5.1 50.1 3.3 10.4 4.1 21.7 9.5 7.1 13.9 18.6 95.4 12.3 7.2 12.0 3.1 7.7 12.0 7.1 3.9 4.5 11.7 17.7 3.6 26.4 15.0 4.5 6.7 2.5 7.3 2.5 17.9 15.1 26.3 2.4 7.9 2.9 3.5 10.0 3.1 2.3 3.9 5.0 16.1 1.2 1.3 1.9 3.1 7.2 1.1 4.0 1.0 0.0 8.0 2.0 17.1 12.4 5.9 2.5 14.6 22.0 47.3 11.6 3.1 5.6 1.1 4.1 11.2 3.8 10.6 15.2 2.2 4.5 9.2 4.0 28.6 26.9 0.0 13.6 4.4 0.1 18.6 11.6 3.4 4.1 32.9 8.5 2.9 1.7 3.1 3.1 7.5 0.0 14.8 6.2 2.6 53.6 1.6 15.8 2.2 1.1 1.8 1.6 2.0 1.2 0.9 1.2 2.7 1.5 50.4 2.2 0.7 1.8 1.5 1.6 1.9 2.8 3.4 3.8 1.7 3.1 4.8 3.0 4.1 3.1 3.9 4.5 16.7 12.8 34.5 0.7 5.5 10.7 18.8 7.2 3.4 3.7 19.4 12.7 69.9 24.3 21.8 9.2 6.2 12.9 7.6 26.7 3.9 8.8 20.3 29.5 21.9 21.0 0.0 0.8 0.8 12.7 38.3 12.7 9.7 51.7 33.6 10.4 31.1 184.7 6.9 6.7 0.4 11.5 8.2 9.8 27.9 5.2 9.6 15.6 5.4 3.7 3.1 3.9 4.1 3.5 1.4 18.4 7.5 18.0 4.5 8.0 7.4 6.8 30.8 13.0 13.1 10.9 17.9 1.7 5.7 0.6 12.1 18.3 10.8 9.4 5.5 2.2 TNKS "ARTD5, PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1" ENSG00000173273 Tankyrase O95271 8 9555912-9782346 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport, Wnt signaling pathway" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 149.9;Excitatory neurons: 203.2;Inhibitory neurons: 230.6;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 285.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025690 Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Nuclear membrane, Nuclear bodies" "HPA025690: AB_10602249" "unprognostic (2.07e-1)" "unprognostic (1.72e-2)" "unprognostic (5.45e-3)" "unprognostic (8.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.27e-2)" "unprognostic (4.75e-2)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (8.01e-2)" "unprognostic (6.21e-2)" "unprognostic (9.10e-2)" "unprognostic (4.14e-2)" "unprognostic (1.12e-1)" "unprognostic (5.43e-1)" "unprognostic (7.76e-2)" "unprognostic (5.36e-2)" 7.3 9.3 14.2 6.5 20.5 12.2 9.9 18.5 15.8 12.1 6.9 7.5 6.0 10.5 17.5 5.9 8.2 6.2 7.0 13.4 16.8 6.1 7.5 6.6 8.5 21.5 18.5 13.1 7.5 12.5 12.6 7.9 22.2 7.8 6.8 21.0 7.1 7.7 18.4 11.4 7.8 7.1 14.7 6.5 7.2 20.3 18.3 10.5 9.7 11.8 8.6 7.9 6.9 32.2 8.8 11.5 28.8 17.4 17.8 23.7 10.7 13.4 15.1 10.7 12.0 6.9 6.9 18.9 5.4 13.2 14.3 9.2 16.5 12.5 15.4 4.9 8.6 13.3 10.7 15.6 16.0 6.9 7.9 16.9 14.8 11.1 21.6 17.3 14.6 14.5 12.7 19.6 19.9 5.8 17.5 10.4 18.9 9.7 6.7 13.9 17.8 5.5 12.8 17.8 29.1 21.4 10.5 9.9 19.3 17.3 6.6 10.2 19.7 17.4 10.6 11.9 10.0 6.7 11.8 13.3 18.7 9.5 17.1 2.4 1.1 0.9 2.0 1.1 1.0 1.9 1.6 1.9 1.4 3.2 1.8 2.2 3.5 1.5 1.4 1.8 0.8 0.7 14.2 20.5 18.5 15.8 13.4 16.8 21.5 18.5 22.2 14.7 18.3 32.2 19.7 16.0 11.7 130.9 23.1 11.5 12.8 11.4 12.0 34.1 15.8 13.6 17.0 15.7 12.0 9.2 14.6 11.2 14.9 9.2 1.9 12.4 149.9 19.9 30.6 15.5 13.8 14.5 203.2 8.5 10.9 20.3 19.9 20.9 10.1 33.7 18.9 18.0 7.1 42.1 230.6 10.8 16.2 9.4 8.5 76.3 16.8 10.3 12.4 92.8 8.4 15.1 5.2 313.1 285.7 13.4 12.8 18.0 20.7 12.8 17.2 6.9 28.1 37.0 0.0 28.7 16.6 37.7 15.4 12.9 15.5 12.3 18.1 39.5 12.2 12.8 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 PRSS51 ENSG00000253649 "Serine protease 51" A0A1B0GVH4 8 10482878-10547585 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 17 "brain: 22.6" "Group enriched" "Detected in some" 10 "Early spermatids: 3.2;Late spermatids: 3.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 12 "cerebellum: 22.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.52e-1)" "unprognostic (3.00e-1)" "unprognostic (3.10e-1)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "unprognostic (2.22e-2)" "unprognostic (2.72e-1)" "unprognostic (7.48e-2)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (1.02e-1)" "unprognostic (6.33e-3)" "unprognostic (2.71e-3)" "unprognostic (7.47e-2)" "unprognostic (3.42e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" 0.0 0.1 0.3 0.1 0.5 0.2 1.1 22.6 1.9 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 22.6 1.9 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 58 "testis: 27.7" "Group enriched" "Detected in some" 46 "Early spermatids: 260.4;Late spermatids: 85.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (3.64e-1)" "unprognostic (8.44e-3)" "unprognostic (6.10e-2)" "unprognostic (7.40e-2)" "unprognostic (6.23e-5)" "unprognostic (6.62e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 260.4 0.0 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 85.4 1.5 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.6 0.1 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RP1L1 DCDC4B ENSG00000183638 "RP1 like 1" Q8IWN7 8 10606349-10712187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 114 "retina: 44.1" "Group enriched" "Detected in some" 20 "Cone photoreceptor cells: 93.8;Rod photoreceptor cells: 68.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024686, HPA024744" Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA024686: AB_2671650, HPA024744: AB_2671668" "unprognostic (3.27e-1)" "unprognostic (9.97e-2)" "unprognostic (1.24e-1)" "unprognostic (6.41e-2)" "unprognostic (2.04e-1)" "unprognostic (1.36e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-5)" "unprognostic (3.57e-1)" "unprognostic (5.22e-2)" "unprognostic (2.08e-4)" "unprognostic (8.52e-2)" "unprognostic (5.77e-2)" "unprognostic (6.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.02e-2)" "unprognostic (2.82e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 44.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.6 0.8 0.1 0.0 4.0 0.2 0.3 0.8 0.0 0.0 0.0 93.8 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.8 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.1 3.3 0.0 0.5 0.6 0.1 0.0 0.4 0.0 0.7 0.0 0.1 0.0 68.0 0.0 1.6 0.5 0.0 0.5 0.0 0.9 0.0 0.1 0.1 0.0 1.0 C8orf74 ENSG00000171060 "Chromosome 8 open reading frame 74" Q6P047 8 10672628-10700590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 171 "testis: 17.0" "Group enriched" "Detected in some" 90 "Early spermatids: 186.5;Late spermatids: 392.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027986 Uncertain Uncertain Nucleoplasm NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "HPA027986: AB_10600762" "unprognostic (4.24e-2)" "unprognostic (5.62e-2)" "unprognostic (4.68e-2)" "unprognostic (5.54e-2)" "unprognostic (2.37e-2)" "unprognostic (1.56e-4)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 186.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 392.8 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SOX7 ENSG00000171056 "SRY-box transcription factor 7" Q9BT81 8 10723768-10730511 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "vagina: 42.4" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal keratinocytes: 61.2;Basal prostatic cells: 67.6;Basal squamous epithelial cells: 148.5;Endothelial cells: 115.1;Squamous epithelial cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 11.8;hTCEpi: 21.3;HUVEC TERT2: 25.2;TIME: 6.8" "Low region specificity" "Detected in many" HPA009065 Approved Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (1.15e-3)" "unprognostic (1.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-1)" "unprognostic (8.74e-2)" "unprognostic (7.26e-2)" "unprognostic (7.44e-2)" "unprognostic (1.09e-1)" "unprognostic (7.71e-3)" "unprognostic (2.45e-3)" "unprognostic (2.38e-1)" "unprognostic (5.41e-3)" "unprognostic (4.84e-3)" 22.6 3.8 2.5 1.0 2.3 0.1 11.9 1.9 2.6 27.0 1.4 4.2 0.1 4.3 1.1 26.8 4.5 3.6 18.5 2.1 1.8 5.1 4.3 23.2 1.7 2.6 2.2 1.5 2.6 1.0 5.6 17.3 2.5 5.4 1.1 0.4 10.5 2.7 9.8 20.2 3.6 2.3 2.5 2.4 3.7 0.7 2.7 1.5 7.6 6.4 1.9 4.6 42.4 2.0 5.8 0.1 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.4 0.3 0.6 11.8 3.4 4.2 0.1 0.1 0.4 0.1 0.3 0.1 0.0 0.2 0.2 0.1 21.3 0.0 4.3 0.0 25.2 0.0 0.6 0.3 0.0 0.2 0.2 0.2 1.6 0.9 3.2 1.2 0.0 0.0 0.0 2.1 0.6 3.4 2.2 0.0 0.0 1.4 0.0 0.1 6.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 2.3 1.9 2.6 2.1 1.8 2.6 2.2 2.5 2.5 2.7 2.0 115.4 0.0 11.5 0.3 1.1 61.2 67.6 24.5 148.5 1.2 5.2 4.7 4.8 1.5 6.3 0.0 4.2 4.3 0.1 0.2 0.0 0.2 0.2 14.9 1.9 115.1 0.0 0.0 4.6 0.2 0.8 4.7 0.0 22.9 3.8 0.5 48.5 4.9 0.7 0.0 2.9 0.2 10.2 1.9 8.7 0.1 0.9 0.9 3.6 10.3 0.3 0.5 0.0 1.5 0.8 0.5 0.0 0.4 1.2 17.8 0.1 0.6 3.2 2.2 0.0 8.5 4.4 2.4 1.6 98.9 40.6 12.4 1.8 1.2 0.4 26.6 PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000258724 "PIN2 (TERF1) interacting telomerase inhibitor 1" 8 10725399-10839847 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 2.9;vagina: 5.5" "Cell type enhanced" "Detected in many" "Early spermatids: 37.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HaCaT: 1.9" HPA009065 Uncertain Approved "Nuclear speckles,Golgi apparatus" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles" "Golgi apparatus" "HPA009065: AB_1857390" "unprognostic (2.57e-1)" "unprognostic (6.34e-2)" 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 2.9 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.1 0.4 0.0 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.7 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.9 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 3.2 6.7 12.4 10.4 26.6 20.7 12.0 14.2 5.6 0.0 0.0 0.0 8.6 8.2 3.7 12.5 0.0 4.0 6.9 11.7 0.0 37.0 0.0 0.0 7.3 8.4 6.9 25.0 0.0 0.0 5.3 7.7 0.0 14.0 0.0 12.5 7.0 0.0 3.3 22.4 5.0 8.2 5.4 10.3 32.7 9.3 3.9 7.2 13.1 3.3 9.0 7.2 17.6 15.3 0.0 5.3 6.4 14.0 20.2 6.5 13.3 7.0 22.1 0.0 12.5 5.5 21.5 22.7 12.0 28.6 0.0 8.3 0.0 9.6 8.9 PINX1 "FLJ20565, Gno1, LPTL, LPTS, MGC8850, Pxr1" ENSG00000254093 "PIN2 (TERF1) interacting telomerase inhibitor 1" Q96BK5 8 10764961-10839884 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 20.0;Extravillous trophoblasts: 13.0;Hofbauer cells: 16.1;Syncytiotrophoblasts: 48.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023139, HPA023146" Uncertain Supported Nucleoplasm,Nucleoli,Mitochondria NA NA "Cluster 35: T-regs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoli "Nucleoplasm, Mitochondria" "HPA023139: AB_1855384, HPA023146: " "unprognostic (4.01e-1)" "prognostic favorable (2.45e-5)" "unprognostic (7.80e-3)" "unprognostic (3.35e-2)" "unprognostic (4.10e-1)" "unprognostic (4.61e-2)" "unprognostic (1.83e-2)" "unprognostic (3.40e-2)" "unprognostic (9.73e-3)" "unprognostic (2.49e-1)" "unprognostic (1.40e-1)" "unprognostic (4.37e-1)" "unprognostic (2.59e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" 9.9 7.7 7.2 8.9 8.4 9.1 9.9 8.9 8.9 9.7 6.1 9.9 6.2 9.3 4.5 12.1 8.8 4.0 8.2 7.4 7.1 11.6 11.7 8.0 11.5 7.2 7.1 9.8 9.0 6.1 6.4 7.2 7.4 8.1 6.1 12.0 7.3 4.2 13.5 14.4 7.7 8.5 7.0 9.3 8.2 9.7 7.4 13.0 8.2 9.3 11.1 10.2 10.5 7.7 14.5 18.9 20.1 19.2 16.6 13.5 23.1 21.5 9.7 23.2 15.6 20.0 12.4 38.5 7.4 11.7 28.3 28.6 51.4 39.9 29.8 15.7 15.3 16.2 13.3 22.0 18.8 17.4 9.7 11.3 24.9 18.3 34.0 8.2 32.7 25.8 52.3 23.1 22.9 17.1 57.7 21.8 46.3 62.6 21.0 46.5 24.5 35.2 17.5 17.5 16.6 17.3 14.5 17.0 48.3 24.3 18.1 21.7 20.0 13.9 30.3 18.0 28.1 10.3 29.0 71.2 14.4 32.6 32.1 1.9 8.4 6.1 14.6 10.7 18.9 12.9 12.8 15.6 11.1 10.8 17.1 13.5 0.5 12.5 9.9 8.6 16.1 10.4 7.2 8.4 8.9 8.9 7.4 7.1 7.2 7.1 7.4 7.0 7.4 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 13.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 48.2 0.0 0.0 0.0 0.0 XKR6 "C8orf21, C8orf5, C8orf7" ENSG00000171044 "XK related 6" Q5GH73 8 10896045-11201833 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 12.9" "Cell type enhanced" "Detected in many" "Astrocytes: 90.1;Excitatory neurons: 419.0;Inhibitory neurons: 339.6;Microglial cells: 106.8;Oligodendrocyte precursor cells: 290.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 4.2;U-266/84: 7.1;U-698: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA024828, HPA064769" Approved "Actin filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "HPA024828: AB_2215165, HPA064769: AB_2732720" "unprognostic (8.63e-3)" "unprognostic (8.45e-2)" "unprognostic (1.50e-1)" "unprognostic (9.92e-6)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (1.18e-1)" "unprognostic (8.75e-3)" "unprognostic (8.65e-2)" "unprognostic (7.09e-2)" "unprognostic (2.87e-1)" "unprognostic (1.31e-1)" "unprognostic (3.78e-2)" "unprognostic (3.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (3.29e-3)" 0.3 0.6 3.3 0.3 4.0 0.7 0.3 12.9 3.7 0.5 0.0 0.5 0.3 0.5 0.1 1.0 0.5 0.2 0.3 3.0 4.7 0.5 0.1 0.6 0.7 2.2 1.3 0.1 1.3 0.3 0.5 0.1 2.1 0.6 0.2 0.4 1.0 0.3 0.1 0.8 0.7 0.2 0.4 0.8 0.7 2.1 4.5 0.2 0.6 0.0 0.4 0.5 0.6 0.7 0.0 0.0 0.9 0.0 0.0 0.0 0.0 1.2 0.4 0.4 1.1 0.0 0.3 3.4 0.0 0.6 1.8 0.1 1.6 1.9 0.6 0.1 0.5 1.0 0.1 0.0 0.5 0.0 2.6 0.3 1.1 0.0 1.4 1.3 0.6 0.0 0.1 4.2 0.5 0.4 0.0 0.0 2.0 0.2 0.8 0.0 0.0 0.9 1.4 1.4 1.9 1.2 0.6 0.1 0.0 1.6 0.0 0.7 0.0 1.6 0.8 0.0 0.5 1.1 7.1 3.6 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.3 4.0 12.9 3.7 3.0 4.7 2.2 1.3 2.1 0.4 4.5 0.7 1.7 6.4 0.5 90.1 9.7 1.8 4.0 1.2 6.2 37.7 4.2 3.0 2.2 5.7 1.6 3.7 14.6 0.0 3.9 1.0 1.9 2.1 10.2 4.6 2.8 2.1 4.2 2.1 419.0 5.3 0.0 1.2 4.6 3.8 0.0 4.3 3.6 0.1 0.5 26.9 339.6 0.7 2.0 1.3 1.5 2.5 0.0 1.4 1.8 106.8 0.5 9.0 3.1 290.0 39.6 3.5 1.4 0.0 10.1 3.0 1.7 0.8 1.8 6.1 0.0 5.6 3.3 6.6 6.1 4.4 1.3 0.0 3.6 3.7 1.3 3.9 MTMR9 "C8orf9, DKFZp434K171, LIP-STYX, MTMR8" ENSG00000104643 "Myotubularin related protein 9" Q96QG7 8 11284816-11328146 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 84.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070944 Approved "Actin filaments,Centrosome" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Centrosome "Actin filaments" "HPA070944: AB_2686325" "unprognostic (1.97e-2)" "unprognostic (1.95e-1)" "unprognostic (2.30e-2)" "unprognostic (1.32e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-2)" "unprognostic (8.09e-3)" "unprognostic (3.25e-1)" "unprognostic (2.05e-1)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-2)" "unprognostic (1.07e-1)" "unprognostic (1.73e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" 4.6 3.7 7.8 4.3 7.9 3.4 4.9 7.0 8.1 3.5 3.3 6.5 2.4 4.5 2.9 3.4 3.1 3.2 7.5 8.4 8.7 4.4 3.0 3.5 4.0 7.2 8.4 3.6 2.9 4.2 3.0 4.2 8.0 5.0 3.1 17.5 2.6 3.9 5.7 3.8 3.1 5.8 6.3 3.8 3.0 7.7 7.4 3.5 3.7 8.6 3.9 3.7 3.2 8.1 2.9 4.2 7.1 4.8 8.4 7.1 5.0 8.7 5.6 5.1 4.3 3.7 1.5 6.8 2.1 8.1 5.0 3.7 5.2 5.3 6.7 1.2 3.8 6.8 4.5 3.4 8.9 2.2 5.0 6.9 5.9 6.2 9.1 5.8 7.8 3.8 5.0 3.9 10.5 2.1 3.9 2.6 12.4 6.9 4.0 3.0 9.7 2.0 7.7 5.1 2.2 10.6 4.6 2.7 6.7 10.5 2.7 5.4 11.2 7.9 2.3 4.8 4.8 1.3 1.9 3.3 6.9 5.6 7.9 0.2 0.4 0.3 0.7 0.4 0.5 0.5 0.6 0.5 0.2 1.1 0.7 0.7 0.5 0.5 0.4 1.0 0.4 0.2 7.8 7.9 7.0 8.1 8.4 8.7 7.2 8.4 8.0 6.3 7.4 8.1 17.8 12.8 16.8 26.4 27.7 13.6 11.6 12.9 11.4 0.0 11.7 8.4 25.3 24.3 14.5 14.7 0.0 12.4 27.4 7.4 3.9 11.6 17.7 5.1 15.0 18.9 16.2 10.8 44.8 7.1 12.7 18.3 4.6 8.0 14.0 24.9 26.7 17.3 14.5 0.0 42.1 10.7 12.2 21.0 32.7 8.5 23.3 20.2 16.0 18.7 24.3 0.0 25.7 32.2 48.7 15.0 11.1 19.5 11.7 21.6 13.4 10.9 18.0 0.0 39.5 19.0 17.7 84.9 33.1 10.1 12.9 4.5 20.7 14.6 9.5 9.3 SLC35G5 "AMAC, AMAC1L2" ENSG00000177710 "Solute carrier family 35 member G5" Q96KT7 8 11331012-11332360 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 13.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 71: Testis - DNA repair" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (7.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.05e-1)" "unprognostic (9.67e-2)" "unprognostic (2.60e-4)" "unprognostic (6.48e-3)" "unprognostic (4.09e-1)" "unprognostic (5.79e-2)" "unprognostic (1.06e-1)" "unprognostic (3.61e-1)" "unprognostic (3.61e-2)" "unprognostic (3.44e-1)" "unprognostic (2.06e-6)" "unprognostic (7.88e-2)" "unprognostic (1.63e-1)" "unprognostic (2.34e-1)" "unprognostic (2.04e-3)" 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.1 2.4 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.1 0.2 0.2 0.0 1.7 0.5 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.1 0.0 0.2 13.8 0.2 0.3 0.4 0.0 0.0 0.3 0.4 0.3 0.2 0.0 0.2 0.0 0.2 2.2 0.1 0.5 1.7 0.3 0.3 2.0 0.3 0.3 1.8 0.0 0.2 0.0 1.0 0.1 0.2 0.0 1.0 0.6 0.4 0.0 0.4 0.1 0.5 0.1 0.0 0.4 3.1 0.0 1.3 0.1 2.3 0.3 0.0 0.1 0.0 0.6 0.1 0.4 0.3 FAM167A "C8orf13, DIORA-1" ENSG00000154319 "Family with sequence similarity 167 member A" Q96KS9 8 11421476-11475908 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.1;thyroid gland: 53.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Astrocytes: 28.4;Distal tubular cells: 13.7;Early spermatids: 24.8;Enteroendocrine cells: 19.1;Late spermatids: 41.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 57.6;RPMI-8226: 61.5;SH-SY5Y: 44.4;U-698: 44.8;U-87 MG: 36.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023915, HPA030426" Approved Approved Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 68: Epididymis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Mitochondria "HPA023915: AB_1845768, HPA030426: AB_10601318" "unprognostic (8.51e-3)" "unprognostic (2.43e-1)" "unprognostic (1.25e-3)" "prognostic unfavorable (5.96e-4)" "unprognostic (3.08e-2)" "unprognostic (4.62e-3)" "unprognostic (1.79e-1)" "unprognostic (1.45e-1)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (4.06e-2)" "unprognostic (7.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.13e-2)" "unprognostic (1.56e-1)" "unprognostic (4.30e-2)" "unprognostic (2.21e-2)" 0.6 0.8 25.8 1.2 25.1 0.7 1.3 23.9 25.3 0.8 17.0 0.7 0.3 0.1 0.5 0.9 1.3 1.0 0.2 26.6 26.7 6.4 0.3 10.2 2.4 29.8 27.6 0.0 2.1 1.7 17.4 0.9 27.9 1.5 0.7 5.2 2.6 4.6 0.0 11.8 1.3 0.0 26.6 1.2 2.0 3.8 31.1 3.0 53.2 0.1 3.0 0.3 1.6 25.1 4.8 3.0 6.1 0.6 0.4 2.5 0.2 16.8 16.0 10.1 4.4 0.2 1.5 57.6 0.9 18.3 4.7 1.6 0.1 4.0 11.9 24.8 0.8 0.0 0.1 0.0 20.8 0.0 0.1 2.9 2.6 5.3 32.2 32.3 0.0 0.0 0.2 2.2 6.0 1.8 0.1 0.0 1.6 0.1 0.1 0.3 0.0 61.5 5.1 0.5 26.3 44.4 0.8 4.7 2.2 0.8 1.8 0.1 28.5 1.0 1.6 25.8 0.2 17.7 14.0 44.8 36.3 0.1 1.6 0.0 0.0 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.0 25.8 25.1 23.9 25.3 26.6 26.7 29.8 27.6 27.9 26.6 31.1 25.1 0.0 16.0 1.8 28.4 5.4 5.9 0.6 0.5 0.0 0.1 1.2 1.3 0.7 1.5 0.5 5.5 10.4 0.0 1.1 0.2 13.7 2.1 24.8 2.1 0.2 0.2 19.1 0.0 0.6 1.8 0.0 0.3 2.6 0.9 0.0 0.0 0.0 0.0 0.1 0.0 1.4 1.3 0.0 0.3 0.3 41.1 0.3 0.3 0.0 3.7 0.3 1.7 0.0 0.0 1.3 1.1 2.4 0.4 0.9 0.8 0.1 0.2 1.9 1.8 0.0 0.3 0.2 3.9 2.2 0.0 3.4 0.0 1.0 0.1 0.1 0.2 BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "intestine: 39.1;lymphoid tissue: 46.7" "Cell type enriched" "Detected in some" 11 "B-cells: 116.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 183.4;naive B-cell: 131.5" "Lineage enriched" "Detected in many" 5 "B-cells: 183.4" "Cell line enhanced" "Detected in some" "Daudi: 106.6;REH: 29.9;RPMI-8226: 38.5;U-698: 48.6;U-87 MG: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "CAB005093: AB_2274756, HPA069571: AB_2732137" "unprognostic (6.50e-5)" "unprognostic (4.22e-3)" "unprognostic (5.64e-2)" "unprognostic (1.42e-1)" "unprognostic (3.45e-1)" "unprognostic (5.98e-6)" "unprognostic (1.59e-2)" "unprognostic (8.94e-4)" "unprognostic (1.02e-3)" "unprognostic (9.83e-3)" "unprognostic (1.22e-2)" "unprognostic (4.66e-2)" "unprognostic (9.05e-6)" "unprognostic (5.62e-2)" "unprognostic (5.43e-2)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" 0.5 0.1 0.0 9.1 0.0 2.6 0.2 0.0 0.0 0.0 0.0 2.6 0.5 0.1 0.0 1.2 0.2 0.5 0.1 0.0 0.0 1.2 0.7 0.8 29.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.0 0.7 0.0 0.3 0.0 39.1 0.1 0.0 46.7 2.1 0.1 0.0 2.5 1.2 0.0 27.9 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 29.9 0.0 38.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 5.4 10.2 48.6 22.7 0.0 0.0 0.2 0.1 0.2 2.0 0.0 37.9 183.4 1.4 4.6 0.1 131.5 0.9 0.4 0.7 0.1 0.1 17.5 1.8 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 116.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.2 0.1 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.0 1.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 4.0 0.1 0.1 0.0 GATA4 ENSG00000136574 "GATA binding protein 4" P43694 8 11676959-11760002 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 88.6;ovary: 95.4;pancreas: 53.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 41.4;Exocrine glandular cells: 33.7;Gastric mucus-secreting cells: 61.2;Granulosa cells: 158.4;Hepatic stellate cells: 57.8;Late spermatids: 37.0;Leydig cells: 41.3;Peritubular cells: 41.3;Theca cells: 80.1" "Cancer enhanced" "Detected in many" "stomach cancer: 21.8;testis cancer: 12.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 19.7;HHSteC: 20.9;OE19: 6.2;SH-SY5Y: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013125, HPA073899" Uncertain Supported "Nuclear bodies" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear bodies" "CAB013125: AB_2533804, HPA073899: AB_2686641" "unprognostic (2.99e-2)" "unprognostic (1.59e-1)" "unprognostic (2.36e-1)" "unprognostic (8.68e-4)" "unprognostic (2.66e-3)" "unprognostic (1.71e-1)" "unprognostic (8.55e-3)" "unprognostic (1.02e-2)" "unprognostic (5.47e-2)" "unprognostic (2.55e-1)" "unprognostic (2.78e-2)" "unprognostic (2.49e-1)" "unprognostic (1.67e-8)" "unprognostic (1.09e-1)" "unprognostic (1.61e-1)" "unprognostic (1.29e-2)" 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 20.2 0.2 0.0 0.0 2.3 4.0 88.6 0.0 0.0 0.0 36.6 0.2 0.0 0.0 0.0 95.4 53.5 0.0 0.1 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.1 35.2 32.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 1.2 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 19.7 20.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.2 1.3 0.0 0.0 1.5 20.5 0.0 0.0 0.1 3.9 1.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.4 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.2 16.1 0.0 0.1 6.1 0.0 0.0 0.1 33.7 0.2 12.0 61.2 0.0 0.0 158.4 57.8 12.1 0.6 0.0 0.1 0.8 0.0 2.8 0.0 37.0 41.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 14.5 0.0 41.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 5.3 2.4 2.2 0.0 0.0 0.8 0.1 80.1 0.9 0.0 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787345 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA073029: AB_2732216, HPA073916: AB_2732245" "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 9.5 27.8 29.2 5.9 28.8 2.3 9.5 27.7 27.9 13.1 23.8 8.6 2.8 9.5 12.5 6.9 15.0 5.7 14.6 29.6 35.6 12.8 16.3 7.4 7.1 32.0 34.3 11.1 11.2 9.0 17.9 6.4 36.8 11.3 4.8 13.4 10.0 8.1 24.5 15.8 6.8 8.5 31.9 12.4 6.9 26.1 36.1 4.7 11.8 13.7 6.9 9.8 8.8 28.3 8.2 22.9 14.1 27.7 6.6 12.2 6.3 13.0 10.6 12.2 8.4 7.1 8.8 3.2 4.9 15.7 26.3 7.1 13.5 14.1 16.7 9.7 6.7 11.3 5.7 13.9 5.3 5.0 8.2 10.8 20.7 10.7 9.9 11.8 11.6 3.7 16.1 10.8 15.0 8.6 0.9 5.2 12.6 33.9 12.1 14.4 18.1 8.8 14.4 12.3 21.5 17.0 10.2 5.3 19.1 11.2 8.4 0.7 14.3 13.9 19.8 3.8 18.4 10.0 22.3 5.7 36.6 16.7 28.8 0.7 2.2 0.2 12.7 3.9 17.5 21.9 12.9 15.3 4.6 16.9 18.7 16.8 1.3 15.1 2.0 8.3 9.3 7.0 29.2 28.8 27.7 27.9 29.6 35.6 32.0 34.3 36.8 31.9 36.1 28.3 7.2 0.0 5.8 6.2 14.0 8.5 17.1 8.0 13.6 32.3 13.1 7.7 19.6 14.3 7.0 7.3 16.7 18.6 5.6 1.5 33.2 21.1 1.1 6.9 8.4 8.9 10.1 10.3 6.3 23.3 15.8 10.3 3.1 3.8 2.5 14.9 7.9 23.6 15.1 8.4 6.9 6.1 14.2 6.9 6.6 2.1 14.0 6.8 14.2 0.0 6.6 38.9 11.3 6.0 3.7 15.1 1.0 24.5 3.8 15.3 0.8 32.2 6.8 17.1 6.6 11.8 10.2 19.0 68.1 8.3 12.8 5.3 9.7 8.9 6.2 12.0 FDFT1 SQS ENSG00000079459 "Farnesyl-diphosphate farnesyltransferase 1" P37268 8 11795573-11839304 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 479.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Daudi: 133.1;RPMI-8226: 361.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008874 Approved Supported "Endoplasmic reticulum" NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "HPA008874: AB_1078844" "unprognostic (2.33e-1)" "unprognostic (2.60e-1)" "prognostic favorable (4.92e-5)" "unprognostic (1.29e-2)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (8.10e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (2.45e-1)" "unprognostic (2.31e-3)" "unprognostic (2.57e-1)" "prognostic favorable (6.59e-9)" "unprognostic (2.28e-1)" "unprognostic (4.06e-2)" "unprognostic (3.86e-1)" "unprognostic (2.06e-1)" 69.1 126.7 8.2 6.7 14.9 15.0 69.5 13.1 11.6 93.3 7.4 113.4 6.7 80.2 2.9 165.7 59.4 3.2 62.9 10.0 11.7 71.3 118.3 88.0 6.0 29.9 14.1 66.9 58.6 2.0 51.2 4.2 23.1 64.5 5.8 5.4 141.7 3.1 160.3 129.0 92.2 4.9 15.4 50.4 113.2 118.7 15.3 3.2 45.9 6.9 4.5 70.4 107.8 31.9 19.1 8.1 28.8 19.4 3.8 5.7 10.9 19.2 10.6 7.4 8.6 8.1 14.1 133.1 3.9 3.2 34.6 17.8 10.6 24.7 8.2 13.1 17.2 9.6 11.1 21.7 7.4 5.5 13.0 11.2 6.0 13.2 4.7 5.3 2.1 24.5 12.1 60.0 4.6 11.1 16.7 12.9 27.1 9.0 5.3 14.9 11.3 361.0 11.9 61.5 9.6 11.2 4.3 11.2 35.9 12.3 11.6 6.8 11.3 5.1 21.6 3.1 5.8 17.0 30.2 26.3 7.5 18.7 19.7 52.1 19.5 25.5 23.1 23.6 20.7 60.5 25.3 24.5 29.1 45.6 25.7 23.3 22.3 26.7 15.1 27.9 45.7 43.9 8.2 14.9 13.1 11.6 10.0 11.7 29.9 14.1 23.1 15.4 15.3 31.9 31.1 54.5 164.1 67.6 78.0 52.5 94.0 479.6 87.6 17.7 79.6 49.8 78.5 101.5 325.8 79.1 14.6 266.2 49.4 134.8 88.0 165.6 294.4 55.0 20.9 45.2 79.1 113.2 29.3 284.4 153.3 37.1 64.2 68.1 57.0 86.2 22.1 221.8 94.1 11.8 25.6 117.4 284.8 41.9 32.2 228.8 77.0 54.3 101.4 38.4 97.1 61.9 55.6 30.2 95.6 163.6 108.4 53.4 50.0 101.3 87.0 74.9 142.6 21.0 52.6 13.8 74.4 215.5 76.1 112.5 88.8 175.0 55.7 131.4 100.4 167.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 DEFB136 DEFB137 ENSG00000205884 "Defensin beta 136" Q30KP8 8 11973937-11974599 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "epididymis: 1.2" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA068255 Enhanced "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA068255: AB_2732780" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB135 ENSG00000205883 "Defensin beta 135" Q30KP9 8 11982321-11984590 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 50 "epididymis: 34.8" "Group enriched" "Detected in some" 9 "Early spermatids: 2.8;Late spermatids: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 2.2" "Region enhanced" "Detected in single" "white matter: 1.5" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.6 0.0 0.5 0.0 0.0 0.0 34.8 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.6 0.3 0.3 0.3 0.2 0.2 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB134 ENSG00000205882 "Defensin beta 134" Q4QY38 8 11993174-11996312 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "epididymis: 13.0" "Group enriched" "Detected in some" 21 "Early spermatids: 48.3;Late spermatids: 33.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Secreted in male reproductive system" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (3.80e-2)" "unprognostic (2.20e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.2 0.0 13.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.1 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DEFB130B ENSG00000233050 "Defensin beta 130B" P0DP73 8 12064389-12071747 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF705D ENSG00000215343 "Zinc finger protein 705D" P0CH99 8 12104389-12115516 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "epididymis: 3.7" "Group enriched" "Detected in some" 40 "Early spermatids: 5.1;Late spermatids: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 34: Spermatids - Unknown function" "unprognostic (2.04e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L7 ENSG00000226430 "Ubiquitin specific peptidase 17 like family member 7" P0C7H9 8 12132417-12134099 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" "unprognostic (5.31e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 USP17L2 DUB3 ENSG00000223443 "Ubiquitin specific peptidase 17 like family member 2" Q6R6M4 8 12137168-12139077 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045642 Uncertain NA NA "HPA045642: AB_2679403" "unprognostic (2.01e-1)" 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.6 0.2 0.5 0.0 0.2 0.3 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM86B1 MGC16279 ENSG00000186523 "Family with sequence similarity 86 member B1" Q8N7N1 8 12182096-12194133 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 5.4;pituitary gland: 6.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 17.5;Proximal tubular cells: 10.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (1.90e-2)" "unprognostic (8.67e-2)" "unprognostic (2.79e-1)" "unprognostic (3.74e-2)" "unprognostic (3.13e-3)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "unprognostic (5.68e-2)" "unprognostic (1.91e-2)" "unprognostic (1.32e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.58e-1)" "unprognostic (7.02e-2)" "unprognostic (2.58e-2)" 0.5 0.7 0.9 0.4 2.2 0.5 1.0 0.2 5.4 2.2 0.0 1.4 0.8 2.3 0.4 0.6 2.4 0.5 0.9 2.6 0.1 1.1 0.3 0.8 0.3 2.0 0.0 3.7 0.9 0.4 6.4 0.1 0.1 2.4 0.0 1.7 0.8 0.3 0.8 1.0 0.6 0.1 0.0 0.6 0.7 0.5 0.5 0.1 1.3 0.0 0.0 1.2 1.5 0.0 0.2 1.2 0.0 2.5 0.0 0.4 1.0 2.0 0.2 0.6 0.3 0.7 0.5 0.5 0.1 0.1 0.7 2.2 0.4 0.7 0.2 0.2 0.3 0.1 0.3 0.3 1.1 0.9 0.9 0.1 0.2 0.2 1.7 0.4 0.1 0.9 0.8 0.7 0.0 1.1 0.0 0.6 0.8 0.7 0.2 0.7 0.5 0.1 0.1 0.6 2.1 0.4 0.2 0.2 0.3 0.2 1.0 0.0 0.0 0.4 0.4 1.8 0.5 0.2 0.6 0.3 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.2 5.4 2.6 0.1 2.0 0.0 0.1 0.0 0.5 0.0 1.2 3.2 1.8 0.7 0.9 1.1 3.1 1.0 3.4 2.1 4.7 5.0 0.5 8.6 3.0 1.8 2.1 1.5 0.4 0.8 5.9 5.1 5.8 4.7 2.3 1.6 4.2 1.3 0.3 1.8 1.6 2.6 1.5 1.5 1.3 17.5 2.5 1.3 1.9 1.7 0.3 1.5 0.0 1.3 0.6 6.2 1.8 0.7 3.6 0.0 0.1 2.7 4.1 0.0 0.1 3.5 0.3 2.6 0.1 7.0 0.8 10.3 8.5 1.7 0.0 3.3 2.1 0.9 0.8 3.8 1.3 1.1 0.8 2.3 2.4 1.8 DEFB130A "DEFB-30, DEFB130, DEFB30" ENSG00000232948 "Defensin beta 130A" P0DP74 8 12310962-12318316 "Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 26 "epididymis: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM86B2 ENSG00000145002 "Family with sequence similarity 86 member B2" P0C5J1 8 12425614-12436343 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Early spermatids: 1.6;Granulosa cells: 2.7;Late spermatids: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTERT-HME1: 5.3;RPMI-8226: 12.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (3.75e-2)" "unprognostic (1.87e-1)" "unprognostic (6.57e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.48e-1)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (6.04e-4)" "unprognostic (9.37e-2)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.13e-2)" 0.3 0.4 0.1 0.1 0.2 0.0 0.4 0.1 0.3 0.6 0.1 0.3 0.1 0.5 0.0 0.9 1.4 0.1 0.1 0.2 0.2 0.5 0.3 0.3 0.0 0.2 0.3 0.6 0.6 0.4 1.0 0.0 0.1 0.4 0.1 0.1 0.3 0.4 0.1 0.3 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.9 0.0 0.0 0.4 0.4 0.1 0.2 0.6 0.1 0.0 0.2 1.1 1.3 0.2 0.6 0.4 1.0 0.4 1.1 0.7 0.0 1.2 0.3 0.2 0.9 1.5 0.0 0.0 0.0 0.2 0.9 0.0 1.0 0.0 0.0 0.3 1.3 1.3 5.3 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.0 0.3 1.0 1.9 0.4 0.1 0.1 12.5 0.0 0.9 1.6 0.0 0.4 1.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.1 0.0 0.2 0.1 0.1 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.7 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 TRMT9B "C8orf79, FLJ36980, hTRM9L, KIAA1456, TRM9L" ENSG00000250305 "TRNA methyltransferase 9B (putative)" Q9P272 8 12945642-13031503 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 118.6;choroid plexus: 375.5" "Cell type enhanced" "Detected in some" "Club cells: 9.9;Collecting duct cells: 14.7;Distal tubular cells: 11.7;Endometrial ciliated cells: 35.1;Glandular and luminal cells: 18.7;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.2" "Region enriched" "Detected in all" 5 "cerebellum: 118.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.0;BJ: 8.7;fHDF/TERT166: 11.9;RPTEC TERT1: 4.0;SCLC-21H: 4.3;U-266/84: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 31.1" HPA024673 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA024673: AB_1845788" "unprognostic (9.85e-3)" "unprognostic (1.20e-1)" "unprognostic (5.54e-4)" "unprognostic (1.06e-2)" "unprognostic (4.08e-2)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (1.93e-1)" "unprognostic (8.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.88e-1)" "prognostic favorable (2.77e-7)" "unprognostic (2.22e-1)" "unprognostic (4.63e-2)" "unprognostic (4.27e-3)" "unprognostic (3.34e-2)" 1.3 0.4 6.1 0.6 6.8 0.3 2.3 118.6 7.9 1.7 375.5 1.6 0.7 1.0 0.9 0.9 2.0 1.6 6.3 25.2 6.3 3.5 2.2 1.7 0.4 5.4 7.2 0.3 2.2 1.6 1.4 0.4 11.5 1.2 1.2 24.5 2.6 1.0 3.2 3.2 1.2 0.4 4.8 1.5 1.1 1.2 17.5 0.2 33.7 1.6 0.3 0.9 0.8 5.0 0.1 0.0 6.0 0.0 0.0 0.0 1.4 8.7 2.0 1.2 0.6 0.0 0.1 0.1 0.4 11.9 1.1 0.2 0.1 0.2 1.2 0.0 0.4 0.2 0.2 0.0 0.0 0.0 0.6 0.2 3.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.1 0.7 0.1 0.0 1.0 0.0 0.1 4.0 0.1 4.3 0.1 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.1 0.8 0.8 0.1 0.2 4.4 0.0 0.0 0.0 1.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 6.1 6.8 118.6 7.9 25.2 6.3 5.4 7.2 11.5 4.8 17.5 5.0 6.2 6.4 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.1 6.7 0.0 0.0 9.9 14.7 0.0 1.0 0.2 0.0 11.7 2.3 0.0 35.1 6.4 2.1 0.0 0.0 0.0 1.1 0.2 1.8 0.0 18.7 1.3 0.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.3 14.6 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 C8orf48 FLJ25402 ENSG00000164743 "Chromosome 8 open reading frame 48" Q96LL4 8 13566869-13568288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Group enriched" "Detected in many" 5 "Early spermatids: 33.3;Late spermatids: 51.9;Spermatocytes: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 13.5;U-87 MG: 11.5;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026107, HPA027440" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 21: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Nucleoplasm "HPA026107: AB_10600765, HPA027440: AB_10601678" "unprognostic (1.67e-2)" "unprognostic (1.28e-1)" "unprognostic (5.07e-2)" "unprognostic (9.01e-2)" "unprognostic (2.31e-2)" "unprognostic (1.13e-1)" "unprognostic (4.84e-3)" "unprognostic (7.70e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-1)" "unprognostic (1.05e-2)" "unprognostic (1.87e-1)" "unprognostic (1.41e-3)" "unprognostic (7.74e-4)" "unprognostic (1.78e-1)" "unprognostic (8.42e-3)" "unprognostic (8.70e-2)" 1.1 0.2 1.1 0.6 2.2 0.0 1.8 1.3 1.6 1.3 0.2 0.5 0.4 1.1 2.9 0.6 1.8 1.2 1.3 1.2 1.2 1.2 0.8 1.2 0.4 2.2 1.5 0.6 0.4 0.3 0.5 0.6 2.6 0.2 0.4 4.8 0.4 0.4 0.1 1.3 0.4 0.9 1.2 0.2 0.9 7.0 1.7 0.2 4.4 0.4 0.2 0.8 0.3 2.9 0.0 0.1 1.8 0.0 6.0 6.0 0.0 5.5 6.1 2.9 4.9 0.0 0.0 0.0 0.0 2.9 13.5 0.6 0.2 1.1 5.7 0.0 0.6 0.6 0.0 0.0 2.1 0.0 0.9 1.9 3.6 3.9 1.0 0.7 3.8 0.0 0.1 0.0 7.4 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 3.2 0.0 0.2 6.3 2.0 0.0 0.0 1.7 5.1 4.9 6.0 5.0 0.0 0.0 0.0 11.5 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.2 1.3 1.6 1.2 1.2 2.2 1.5 2.6 1.2 1.7 2.9 1.0 0.0 0.0 2.0 0.0 1.0 0.0 1.0 0.0 0.2 0.9 0.8 0.3 0.0 0.9 0.0 2.1 0.0 0.0 0.1 0.0 2.7 33.3 1.8 3.0 0.7 0.0 0.0 0.6 1.1 0.0 2.7 0.0 0.2 0.0 0.3 1.1 0.5 0.1 0.0 0.3 0.0 2.0 0.0 0.0 51.9 5.0 0.2 5.4 0.0 0.0 1.4 0.0 0.0 0.1 0.2 0.0 3.0 0.0 0.0 0.0 3.6 1.9 4.3 6.6 1.2 4.5 18.2 2.3 0.8 0.4 0.0 0.1 3.4 0.0 0.1 SGCZ ZSG1 ENSG00000185053 "Sarcoglycan zeta" Q96LD1 8 14084845-15238431 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.3;ovary: 1.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 477.1;Inhibitory neurons: 2304.3;Oligodendrocyte precursor cells: 1235.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA017585 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA017585: AB_1856799" "unprognostic (3.83e-1)" "unprognostic (1.41e-1)" "unprognostic (5.87e-4)" "unprognostic (1.21e-1)" 0.1 0.0 0.9 0.0 0.7 0.0 0.4 1.7 1.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.3 0.1 0.0 0.0 0.0 0.7 2.3 1.6 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 1.7 1.2 0.6 2.3 0.7 2.3 0.7 0.5 2.1 0.4 0.0 0.0 0.0 47.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 477.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2304.3 0.0 0.0 0.0 0.0 0.7 0.9 0.1 0.0 73.1 0.0 0.1 0.0 1235.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TUSC3 "MagT2, MGC13453, MRT22, MRT7, N33, OST3A, SLC58A2" ENSG00000104723 "Tumor suppressor candidate 3" Q13454 8 15417215-15766649 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 472.9;Extravillous trophoblasts: 321.8;Syncytiotrophoblasts: 783.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049851, HPA049974" Approved NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "HPA049851: AB_2680913, HPA049974: AB_2680976" "unprognostic (3.31e-2)" "unprognostic (7.17e-2)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-1)" "unprognostic (2.34e-1)" "unprognostic (7.15e-3)" "unprognostic (5.02e-2)" "unprognostic (7.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-3)" "unprognostic (4.81e-1)" "unprognostic (1.60e-3)" "unprognostic (5.99e-3)" "unprognostic (1.17e-1)" "prognostic favorable (7.86e-4)" "unprognostic (1.55e-1)" 23.3 68.8 18.7 8.4 18.4 0.1 28.3 22.3 17.1 25.0 46.6 14.5 9.3 31.9 100.8 11.8 57.6 16.7 34.9 17.1 48.2 25.2 6.9 18.4 6.8 8.9 11.6 73.6 35.0 54.0 69.6 80.5 8.9 46.4 15.5 40.9 12.1 29.7 4.5 8.2 8.2 32.5 7.7 5.3 10.8 23.2 21.0 7.5 9.5 5.7 5.6 34.0 13.0 8.0 52.1 38.4 104.3 96.7 125.2 126.7 0.2 74.9 168.8 85.2 139.3 0.1 0.1 0.7 24.5 105.9 92.4 39.3 37.5 76.1 116.0 0.1 49.8 0.0 30.1 6.0 51.9 0.2 5.6 111.8 22.8 121.0 43.1 113.7 6.9 15.9 70.9 15.6 123.2 41.2 20.6 0.4 49.2 0.0 33.5 24.8 88.7 0.3 108.3 127.1 40.7 74.6 0.0 40.6 56.5 76.2 49.8 0.2 29.0 71.9 71.3 31.3 36.5 0.0 10.0 0.4 1.2 0.0 102.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 18.4 22.3 17.1 17.1 48.2 8.9 11.6 8.9 7.7 21.0 8.0 88.6 0.0 10.3 13.4 0.6 9.9 61.1 123.5 63.7 50.4 40.0 52.1 47.5 18.6 47.0 79.1 8.4 472.9 0.9 2.1 17.6 179.0 11.5 100.8 48.6 36.2 95.7 0.0 141.0 12.2 321.8 53.4 7.7 35.0 1.3 39.3 7.5 0.0 41.8 32.0 155.3 26.3 95.6 0.0 6.3 7.6 34.8 1.5 24.9 24.4 1.6 35.9 0.0 61.3 3.9 23.8 4.1 23.0 2.6 63.8 0.0 23.7 172.4 28.1 39.5 2.0 49.7 60.9 47.4 26.2 4.1 783.8 1.6 46.6 7.8 51.4 MSR1 "CD204, SCARA1, SR-A, SR-AI, SR-AII, SR-AIII" ENSG00000038945 "Macrophage scavenger receptor 1" P21757 8 16107878-16567490 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lung: 120.1" "Group enriched" "Detected in many" 5 "Hofbauer cells: 137.3;Kupffer cells: 322.8;Langerhans cells: 86.0;Macrophages: 172.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 16.9" "Lineage enriched" "Detected in many" 5 "monocytes: 16.9" "Group enriched" "Detected in many" 7 "BJ hTERT+: 105.2;REH: 40.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA000272, CAB032491" Enhanced NA NA 67000 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "CAB032491: AB_672722, HPA000272: AB_1846269" "unprognostic (8.19e-3)" "unprognostic (4.87e-2)" "unprognostic (1.93e-2)" "unprognostic (2.10e-1)" "unprognostic (9.24e-2)" "unprognostic (1.32e-2)" "unprognostic (5.85e-3)" "unprognostic (2.89e-1)" "unprognostic (9.70e-2)" "unprognostic (1.62e-2)" "unprognostic (7.19e-2)" "unprognostic (8.82e-2)" "unprognostic (2.76e-2)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (6.85e-2)" "unprognostic (4.69e-2)" 25.9 18.4 4.2 17.5 5.4 13.0 9.7 5.5 10.6 11.6 13.6 8.5 6.6 8.0 6.3 6.2 5.6 29.8 8.7 3.8 6.5 6.7 24.9 120.1 7.0 15.0 7.5 6.1 11.4 6.3 2.6 27.4 10.8 3.6 10.6 5.9 6.3 6.4 2.3 3.5 9.4 17.9 6.9 16.0 6.2 6.2 16.9 4.4 5.2 1.4 2.9 17.4 1.9 22.9 1.5 2.1 3.0 1.5 1.4 1.3 1.4 0.7 105.2 0.3 0.6 3.7 0.4 3.4 5.1 1.0 0.7 0.7 0.7 1.0 2.0 0.4 4.3 4.6 5.1 4.2 0.9 2.4 2.5 0.7 0.8 0.8 1.5 1.8 0.2 1.9 1.7 2.9 1.9 4.3 1.4 1.4 0.5 1.6 1.3 40.7 2.3 1.0 2.0 5.8 2.8 1.2 1.0 2.8 0.2 5.0 0.4 1.2 2.4 2.8 0.9 10.8 2.8 9.5 8.6 7.4 1.1 1.5 2.2 1.7 3.3 0.6 1.0 16.9 0.4 1.1 0.7 0.7 1.1 1.5 1.3 0.9 3.2 0.4 8.8 0.5 0.7 0.8 4.2 5.4 5.5 10.6 3.8 6.5 15.0 7.5 10.8 6.9 16.9 22.9 2.0 22.4 35.9 0.0 2.7 2.7 0.0 0.0 0.0 1.6 0.5 1.4 2.0 2.8 8.1 3.7 25.0 0.5 0.1 0.0 1.9 0.0 2.9 0.0 0.0 6.3 0.0 2.7 0.3 0.0 1.0 2.1 0.0 0.0 17.7 0.1 4.6 1.7 137.3 0.0 3.0 0.1 0.0 322.8 86.0 3.6 1.8 172.5 0.0 28.1 3.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.4 6.6 0.7 19.7 1.0 0.7 4.2 1.3 0.1 2.0 0.8 2.6 0.2 0.0 0.3 FGF20 ENSG00000078579 "Fibroblast growth factor 20" Q9NP95 8 16992181-17002345 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5" "Cell type enriched" "Detected in some" 7 "Microglial cells: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;CAPAN-2: 5.3;OE19: 1.2" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Secreted in other tissues" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "unprognostic (1.93e-2)" "unprognostic (2.19e-1)" "unprognostic (5.57e-3)" "unprognostic (3.95e-2)" "unprognostic (1.59e-3)" "unprognostic (1.40e-2)" "unprognostic (1.94e-1)" "unprognostic (2.65e-2)" "unprognostic (9.32e-2)" "unprognostic (9.95e-2)" "unprognostic (3.92e-1)" "unprognostic (4.08e-2)" 0.1 0.6 0.8 0.0 0.8 0.0 0.2 2.5 1.4 0.9 0.5 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.1 0.8 1.2 0.0 0.0 0.1 0.1 1.1 1.2 0.6 0.1 0.0 0.4 0.1 1.4 0.2 0.0 0.1 1.1 0.1 0.0 0.0 0.1 0.0 1.1 1.0 0.6 0.2 1.4 0.2 0.2 0.0 0.4 0.1 0.1 1.6 0.0 0.0 0.1 0.0 0.4 0.6 0.0 0.6 1.6 0.2 0.8 0.0 5.3 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.8 2.5 1.4 0.8 1.2 1.1 1.2 1.4 1.1 1.4 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 1.0 0.0 0.0 0.0 1.2 0.0 8.4 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 MICU3 "DKFZp313A0139, EFHA2" ENSG00000155970 "Mitochondrial calcium uptake family member 3" Q86XE3 8 17027238-17122642 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.9;Excitatory neurons: 161.4;Inhibitory neurons: 167.3;Oligodendrocyte precursor cells: 96.5;Oligodendrocytes: 141.9;Rod photoreceptor cells: 82.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HBF TERT88: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024771, HPA024779" Uncertain NA NA "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA024771: AB_1848022, HPA024779: AB_1848023" "unprognostic (2.99e-2)" "unprognostic (7.73e-2)" "unprognostic (7.88e-2)" "unprognostic (3.80e-2)" "unprognostic (1.19e-1)" "unprognostic (7.49e-2)" "unprognostic (2.25e-2)" "unprognostic (9.01e-5)" "unprognostic (9.82e-2)" "unprognostic (2.80e-1)" "unprognostic (1.11e-3)" "unprognostic (8.45e-2)" "unprognostic (2.32e-2)" "unprognostic (3.03e-3)" "unprognostic (2.12e-1)" "unprognostic (2.40e-1)" "unprognostic (4.65e-2)" 6.4 7.5 8.7 1.5 11.2 0.6 4.4 23.2 19.5 6.3 0.3 3.8 0.9 6.7 4.2 3.0 4.5 3.6 4.4 11.3 7.8 4.4 10.3 3.4 2.6 6.7 5.6 8.2 2.9 7.7 8.2 6.7 6.8 5.9 1.9 14.9 3.2 4.4 3.6 1.8 2.1 4.8 5.9 4.6 2.6 5.3 7.7 1.4 5.0 6.5 1.9 4.9 4.2 11.6 0.0 1.2 6.0 2.3 4.5 6.7 1.5 9.0 12.7 6.8 5.5 0.0 0.2 0.2 1.8 4.7 4.8 0.0 2.7 1.8 12.7 0.0 1.6 0.0 0.0 2.2 7.8 0.0 0.3 5.1 0.0 5.7 5.7 6.3 2.6 4.6 0.4 1.7 6.4 0.0 0.8 1.1 4.2 0.0 1.5 0.0 2.7 0.0 4.7 0.0 9.8 4.6 0.0 0.0 3.7 2.6 0.0 0.0 3.4 2.9 1.1 0.4 1.6 1.7 1.4 3.1 5.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 8.7 11.2 23.2 19.5 11.3 7.8 6.7 5.6 6.8 5.9 7.7 11.6 18.2 6.4 6.0 68.9 12.3 0.9 8.1 0.4 12.0 82.9 5.8 12.7 15.5 10.0 2.0 5.5 41.7 1.8 2.9 0.0 7.9 5.4 6.8 0.9 30.2 10.0 0.0 4.2 161.4 2.9 1.2 19.0 2.6 1.0 8.2 14.3 7.1 14.1 0.6 74.0 167.3 0.0 0.0 2.2 1.5 7.2 27.4 2.7 1.8 68.4 1.6 24.0 3.1 96.5 141.9 2.8 0.0 24.0 0.9 5.6 0.0 3.9 1.7 82.2 39.5 14.9 40.1 23.7 11.8 3.1 1.6 7.3 4.6 34.1 0.0 2.7 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 CNOT7 CAF1 ENSG00000198791 "CCR4-NOT transcription complex subunit 7" Q9UIV1 8 17224966-17246878 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069543 Supported "Nuclear bodies" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear bodies" "HPA069543: AB_2686148" "unprognostic (1.55e-1)" "unprognostic (4.49e-2)" "prognostic favorable (4.99e-4)" "unprognostic (4.61e-2)" "unprognostic (8.45e-2)" "unprognostic (3.10e-2)" "unprognostic (1.44e-3)" "unprognostic (4.54e-2)" "unprognostic (6.83e-2)" "unprognostic (4.09e-3)" "unprognostic (2.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.49e-2)" "unprognostic (1.72e-1)" "unprognostic (4.51e-1)" "unprognostic (2.24e-1)" "unprognostic (2.52e-1)" 31.9 32.7 21.6 39.8 25.4 51.0 42.1 35.0 30.7 28.0 20.5 43.0 38.3 39.5 45.1 43.7 36.3 35.7 38.2 24.2 26.8 50.8 48.8 33.0 52.2 19.7 23.3 42.1 36.0 62.6 26.2 43.1 20.3 32.7 43.8 78.0 38.5 29.5 78.9 27.8 38.4 36.6 21.5 39.0 32.0 52.0 24.4 80.2 60.0 72.2 64.9 45.0 20.4 24.0 77.3 93.6 138.1 103.1 57.0 59.6 95.3 97.6 82.5 110.4 97.5 110.2 60.4 106.1 103.9 85.9 177.5 60.3 147.0 122.9 160.2 44.1 71.0 139.9 68.6 119.9 73.2 95.3 82.8 57.3 99.7 94.3 100.3 102.0 133.7 138.2 119.1 114.9 112.9 60.2 234.7 88.2 152.6 144.4 72.0 126.1 102.7 79.9 95.6 167.6 173.6 115.9 68.6 60.3 114.4 112.9 72.5 79.2 90.8 82.0 116.5 92.4 110.8 59.3 208.2 189.5 76.9 88.7 82.8 138.0 93.9 109.5 80.2 116.6 95.3 133.3 109.7 95.7 113.5 135.3 136.6 110.0 84.5 106.5 105.1 101.3 134.8 130.1 21.6 25.4 35.0 30.7 24.2 26.8 19.7 23.3 20.3 21.5 24.4 24.0 46.9 32.1 40.3 15.0 100.4 90.9 65.2 82.5 100.7 114.9 77.1 64.0 58.2 61.5 48.2 62.5 93.8 88.4 74.5 31.0 97.8 79.0 86.5 50.7 37.1 56.8 94.1 60.5 39.1 72.5 115.1 45.9 40.2 53.5 44.9 72.2 69.3 67.2 69.7 25.2 32.1 69.6 81.4 73.5 58.7 33.9 40.7 59.4 26.6 28.1 83.7 68.5 76.2 23.1 34.8 79.3 58.1 40.6 84.0 93.8 52.6 113.9 56.6 219.2 78.9 51.6 56.2 95.9 100.7 90.7 86.0 85.5 77.6 55.3 70.5 84.3 VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Centrosome, Cytosol" "HPA024705: AB_10601776, HPA024781: AB_10602100" "unprognostic (8.28e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-3)" "unprognostic (3.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.31e-2)" "unprognostic (5.88e-3)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (2.18e-1)" 18.9 19.4 11.9 14.8 15.1 15.4 18.5 28.7 17.5 21.1 5.0 16.8 20.9 19.4 14.3 20.2 13.7 16.8 36.2 10.1 13.6 25.0 27.8 16.2 14.2 11.2 12.5 18.4 17.5 33.8 12.4 29.7 12.1 20.2 17.2 55.0 12.5 23.2 39.4 14.7 17.5 24.4 10.0 12.3 14.5 32.3 12.2 17.5 18.9 31.2 15.2 25.1 15.0 18.4 17.2 27.3 24.0 21.7 51.8 41.5 25.8 60.8 50.2 53.9 45.9 17.6 16.2 14.6 31.6 48.7 50.1 16.7 27.2 26.4 63.8 15.1 7.8 26.5 13.7 20.2 59.7 11.3 25.1 39.7 50.2 50.4 51.5 38.0 38.7 22.7 20.2 36.8 57.7 11.7 32.0 26.9 23.4 38.2 14.2 15.4 26.5 17.6 45.8 23.4 27.1 14.4 23.8 23.9 37.9 47.1 15.6 22.2 33.4 33.1 16.7 47.6 32.0 12.0 25.0 17.2 37.5 19.9 33.8 34.0 17.2 16.5 13.9 13.1 17.1 10.5 13.4 13.6 13.4 10.8 12.0 14.8 17.6 24.5 12.4 11.8 13.3 14.1 11.9 15.1 28.7 17.5 10.1 13.6 11.2 12.5 12.1 10.0 12.2 18.4 31.8 16.0 15.6 19.6 21.2 39.5 32.7 33.1 18.8 26.4 19.3 13.5 40.7 14.3 25.8 7.3 58.4 36.1 20.5 15.8 37.2 29.3 93.2 20.9 29.0 24.6 18.0 26.1 32.4 15.5 59.2 27.0 15.8 28.4 9.5 16.8 24.3 23.1 44.6 21.9 30.7 16.6 30.5 17.5 22.7 39.6 25.7 25.3 21.4 20.6 22.4 25.8 15.5 24.1 34.0 31.2 13.1 25.9 21.5 50.6 27.8 48.8 18.8 60.2 26.3 21.5 36.6 111.6 43.4 22.5 37.8 113.0 22.7 17.1 14.6 52.6 MTMR7 ENSG00000003987 "Myotubularin related protein 7" Q9Y216 8 17296794-17413528 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;retina: 28.4" "Group enriched" "Detected in some" 8 "Excitatory neurons: 79.2;Inhibitory neurons: 116.4;Oligodendrocyte precursor cells: 83.9;Oligodendrocytes: 171.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 3.7;SCLC-21H: 9.5;SH-SY5Y: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075682 Approved Nucleoplasm,Cytosol NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA075682: " "unprognostic (1.01e-1)" "unprognostic (6.10e-2)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (1.67e-1)" "unprognostic (1.31e-2)" "unprognostic (4.15e-2)" "unprognostic (1.41e-2)" "unprognostic (1.92e-1)" "unprognostic (2.45e-1)" "unprognostic (2.07e-4)" "unprognostic (1.46e-2)" "unprognostic (1.97e-7)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (4.17e-2)" "unprognostic (2.66e-3)" 1.4 2.1 6.3 0.7 6.9 1.7 0.8 9.0 8.2 1.1 0.0 0.9 0.7 0.9 0.1 0.6 1.1 0.5 0.7 8.2 5.2 0.9 1.3 1.0 0.6 5.9 6.0 2.2 1.2 3.8 6.9 0.6 7.5 0.7 0.3 28.4 0.6 0.2 1.0 1.3 1.0 0.2 5.8 0.7 0.9 1.4 9.2 0.1 3.0 0.2 0.0 0.8 0.8 11.9 0.5 0.4 0.8 0.6 0.0 0.0 0.7 1.3 0.0 0.0 0.0 0.7 0.2 0.6 0.3 0.0 0.5 0.2 2.6 0.0 0.0 0.1 2.1 0.9 1.2 0.4 0.7 0.5 0.6 0.1 0.0 0.0 0.0 0.6 0.1 0.3 0.4 0.5 0.0 0.4 0.9 1.2 3.7 0.5 0.4 0.3 1.1 0.4 0.0 2.3 9.5 5.5 0.4 0.5 0.7 1.3 0.2 0.6 1.1 0.6 0.3 1.4 0.8 0.2 0.3 0.4 1.8 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.3 6.9 9.0 8.2 8.2 5.2 5.9 6.0 7.5 5.8 9.2 11.9 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.7 0.0 0.0 0.0 0.0 2.3 0.2 0.1 0.0 0.0 14.0 0.5 0.4 0.2 3.6 0.4 79.2 0.5 0.5 0.5 1.5 1.1 0.0 0.0 0.0 0.0 0.4 0.0 116.4 0.1 0.0 0.0 0.0 5.6 0.0 0.0 0.0 5.6 0.0 0.0 0.0 83.9 171.9 0.2 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 6.6 0.2 1.5 0.9 1.8 0.4 0.1 1.4 0.1 0.1 0.0 0.0 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 PDGFRL PRLTS ENSG00000104213 "Platelet derived growth factor receptor like" Q15198 8 17576433-17644071 "Disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Fibroblasts: 186.2;Leydig cells: 74.6;Peritubular cells: 70.7" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 189.4;BJ hTERT+: 159.1;HSkMC: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052801 Approved "Nucleoplasm,Nucleoli,Golgi apparatus" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA052801: AB_2681956" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (5.10e-2)" "unprognostic (1.59e-2)" "unprognostic (7.39e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (6.54e-2)" "unprognostic (3.86e-1)" "unprognostic (7.46e-2)" "unprognostic (1.63e-1)" "unprognostic (6.72e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.58e-3)" "unprognostic (1.26e-1)" "unprognostic (4.47e-3)" "unprognostic (6.00e-3)" 34.1 4.2 2.5 3.9 3.5 0.2 51.9 2.8 3.0 27.8 1.9 9.0 0.9 15.8 10.3 3.0 23.3 13.4 11.1 2.3 2.3 1.3 0.7 4.7 1.2 2.7 2.6 42.9 6.9 9.0 7.4 9.0 2.5 5.4 3.1 0.6 13.1 6.7 18.4 11.0 2.6 26.0 2.4 0.8 6.2 6.5 2.9 3.8 33.0 38.0 2.0 6.5 12.0 3.3 0.0 17.7 1.0 189.4 5.6 2.5 13.8 4.6 159.1 7.5 31.3 1.0 0.2 0.0 0.9 2.5 24.7 0.0 11.6 0.9 3.7 0.2 14.5 0.0 5.3 4.1 14.6 0.0 0.0 86.9 0.1 9.2 0.1 0.0 13.0 1.6 0.0 2.4 1.1 12.5 0.2 0.4 9.9 0.7 3.6 0.0 0.2 0.4 1.0 11.4 0.6 1.2 1.4 1.7 3.3 11.4 0.6 0.0 2.6 0.2 6.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.5 2.8 3.0 2.3 2.3 2.7 2.6 2.5 2.4 2.9 3.3 15.5 0.0 3.6 2.3 0.3 13.3 0.5 4.3 0.6 0.6 2.9 3.3 4.5 1.5 2.8 0.0 0.0 14.9 0.7 0.4 0.0 4.1 36.0 2.4 5.4 4.1 1.2 0.0 1.1 7.1 19.9 186.2 0.5 4.7 0.0 0.3 1.4 0.2 3.5 0.0 3.5 1.3 2.0 0.0 14.6 6.7 74.6 1.6 10.6 1.9 1.6 1.4 0.0 3.0 1.3 3.1 0.1 70.7 0.2 1.9 0.4 0.1 0.2 0.4 0.0 8.0 10.7 0.8 1.9 0.6 9.9 9.7 1.7 1.5 0.4 0.5 MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17800917 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 408.9;Alveolar cells type 2: 281.0;Oligodendrocytes: 469.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "A549: 115.7;AN3-CA: 100.1;HUVEC TERT2: 296.8;SK-MEL-30: 84.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 32: T-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoli, Microtubules" "HPA067903: AB_2685921, HPA069795: AB_2686198" "unprognostic (3.20e-1)" "unprognostic (3.29e-1)" "prognostic favorable (1.05e-4)" "unprognostic (2.50e-2)" "unprognostic (2.27e-1)" "unprognostic (7.72e-3)" "unprognostic (1.36e-1)" "unprognostic (1.86e-3)" "unprognostic (2.44e-1)" "unprognostic (9.73e-2)" "unprognostic (7.93e-3)" "unprognostic (3.33e-1)" "prognostic favorable (2.76e-4)" "unprognostic (2.04e-1)" "unprognostic (2.38e-2)" "unprognostic (2.53e-3)" "unprognostic (2.43e-1)" 52.9 39.0 65.6 13.4 100.4 0.3 45.0 97.4 81.7 34.5 59.3 36.6 32.6 31.4 22.6 38.0 28.7 37.9 85.6 66.0 76.9 26.2 56.8 40.4 9.0 106.4 90.8 51.4 98.2 65.2 22.9 70.0 104.2 31.9 39.1 56.9 49.9 24.7 106.2 26.0 33.4 38.2 75.7 16.1 42.2 12.2 87.6 22.8 27.3 167.4 14.5 35.8 31.0 151.1 21.9 115.7 18.5 100.1 0.1 0.6 33.2 1.1 7.8 0.6 2.3 8.7 7.8 2.8 8.5 0.0 4.8 22.2 30.8 10.9 1.1 15.8 13.2 0.0 19.2 55.8 6.6 0.0 0.4 9.1 16.4 2.4 33.3 0.0 296.8 7.7 0.0 43.3 0.1 5.7 4.4 5.7 26.5 44.1 2.9 0.1 17.0 11.5 5.9 44.4 9.2 2.2 14.8 26.6 84.7 11.0 19.2 0.3 61.4 0.1 24.0 0.1 0.2 5.9 3.5 0.0 0.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.8 1.4 0.0 0.0 0.0 0.0 0.0 0.4 65.6 100.4 97.4 81.7 66.0 76.9 106.4 90.8 104.2 75.7 87.6 151.1 408.9 70.5 281.0 139.1 2.9 21.0 56.4 38.9 58.1 0.0 42.7 31.6 141.6 55.8 88.4 20.2 0.0 23.8 1.6 58.5 11.7 50.1 18.5 71.4 53.8 154.5 15.0 0.0 6.1 174.2 40.0 83.8 94.8 144.2 9.5 7.6 29.3 71.2 58.2 0.0 81.8 47.3 22.4 4.1 16.1 24.5 76.4 9.0 28.4 174.3 2.7 0.0 2.1 39.2 469.2 56.5 19.1 57.2 15.3 77.9 52.4 10.4 49.4 0.0 19.7 69.7 60.1 2.4 8.3 45.3 20.3 54.0 7.1 79.8 49.3 81.3 FGL1 "HFREP-1, HPS" ENSG00000104760 "Fibrinogen like 1" Q08830 8 17864380-17910365 "Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 4163.9" "Cell type enriched" "Detected in many" 27 "Hepatocytes: 8261.7" "Cancer enriched" "Detected in some" 40 "liver cancer: 399.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 15 "A549: 55.4;Hep G2: 131.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 57000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (1.75e-5)" "unprognostic (3.00e-1)" "unprognostic (3.54e-2)" "unprognostic (7.89e-2)" "unprognostic (2.15e-1)" "unprognostic (2.62e-1)" "unprognostic (2.71e-1)" "unprognostic (1.09e-2)" "unprognostic (2.86e-7)" "prognostic unfavorable (5.38e-4)" "unprognostic (3.62e-1)" "unprognostic (2.58e-2)" "unprognostic (1.35e-1)" 0.9 0.4 1.2 0.0 1.4 0.0 1.0 1.0 1.8 0.4 0.9 0.2 0.0 0.7 0.7 0.2 0.2 0.1 0.3 1.3 1.7 0.5 4163.9 1.2 0.0 1.3 1.6 0.3 660.1 0.0 0.2 6.3 1.3 3.8 0.1 0.2 0.2 0.0 0.1 0.1 0.3 0.2 1.1 3.8 0.6 4.3 1.5 0.0 0.3 0.0 0.0 0.1 0.1 1.2 0.0 55.4 0.0 6.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 131.9 0.0 1.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.2 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 1.3 0.8 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.4 1.0 1.8 1.3 1.7 1.3 1.6 1.3 1.1 1.5 1.2 0.0 0.0 1.9 12.4 24.6 0.0 0.2 0.0 0.0 0.0 1.3 0.9 2.1 301.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 8.3 42.9 5.4 1.0 7.6 0.0 176.4 0.1 71.2 0.4 0.1 0.0 7.8 0.0 0.0 173.8 8261.7 20.4 0.0 0.3 0.0 0.0 231.6 0.0 32.7 0.6 0.2 0.0 14.0 1.6 0.0 0.0 2.5 0.0 74.1 0.0 0.4 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.7 0.0 0.0 1.0 12.8 0.1 0.3 0.2 PCM1 PTC4 ENSG00000078674 "Pericentriolar material 1" Q15154 8 17922840-18027975 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 528.5;Spermatocytes: 569.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023370, HPA023374, CAB058695" Enhanced Supported "Centriolar satellite,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Centriolar satellite" Cytosol "CAB058695: AB_2665588, HPA023370: AB_1855072, HPA023374: AB_1855073" "unprognostic (1.52e-2)" "unprognostic (1.77e-2)" "unprognostic (6.54e-3)" "unprognostic (3.35e-2)" "unprognostic (9.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.74e-3)" "unprognostic (1.09e-1)" "unprognostic (2.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.83e-1)" "unprognostic (1.76e-2)" "unprognostic (2.16e-1)" "unprognostic (4.60e-1)" "unprognostic (1.34e-1)" "unprognostic (2.45e-1)" 29.5 31.3 32.9 28.1 39.7 52.2 43.1 42.7 37.0 39.3 39.9 37.3 21.8 39.3 41.6 28.1 44.1 30.7 38.6 31.7 35.0 33.0 39.2 33.6 41.5 35.5 34.2 47.0 39.9 52.6 31.0 35.2 37.2 33.5 27.4 76.6 35.1 32.2 105.3 30.4 29.5 30.6 32.8 33.4 27.9 154.2 35.8 56.9 49.0 84.9 37.3 31.0 26.2 47.0 64.0 66.8 100.5 133.4 55.2 57.0 51.7 52.6 64.4 54.9 61.3 45.4 37.0 83.0 35.3 52.8 47.2 45.0 64.8 48.3 93.0 27.6 25.1 142.7 46.2 93.1 61.6 63.7 35.1 50.3 50.6 63.9 70.3 47.9 64.1 84.9 98.4 62.6 67.9 32.0 136.8 103.3 82.7 52.8 19.1 81.0 90.1 30.0 45.3 87.1 76.6 57.6 56.5 30.5 82.1 42.8 48.2 91.0 57.8 49.6 40.5 61.3 45.0 26.6 62.9 72.5 41.8 68.3 52.0 31.5 7.2 18.7 13.0 4.6 13.5 13.0 11.6 15.1 7.3 13.1 12.9 13.2 7.6 13.9 10.0 17.8 13.1 5.6 32.9 39.7 42.7 37.0 31.7 35.0 35.5 34.2 37.2 32.8 35.8 47.0 91.6 128.2 154.9 187.7 109.3 33.8 66.3 44.4 75.7 196.1 74.1 72.0 249.4 62.9 117.2 86.5 350.3 50.9 145.9 33.6 29.4 73.0 528.5 275.2 130.4 86.5 71.2 115.5 219.9 59.0 33.6 100.4 55.0 132.5 142.1 103.9 64.6 50.8 43.3 129.5 211.8 45.7 61.1 61.3 39.7 301.3 92.2 83.6 55.2 162.1 82.8 145.8 132.8 208.6 243.1 58.9 36.0 97.8 84.7 45.8 45.6 25.9 282.1 234.9 124.9 173.8 92.7 569.3 177.1 65.4 38.2 60.5 122.5 92.1 50.6 47.2 ASAH1 "AC, ACDase, ASAH, FLJ21558, PHP32" ENSG00000104763 "N-acylsphingosine amidohydrolase 1" Q13510 8 18055992-18084998 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 573.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 777.0;Hofbauer cells: 921.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 392.8;SK-MEL-30: 590.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005468 Supported "Intracellular and membrane" NA NA 400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "HPA005468: AB_1845062" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.15e-3)" "unprognostic (9.23e-2)" "unprognostic (4.69e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (4.29e-3)" "unprognostic (2.44e-1)" "unprognostic (4.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.03e-2)" "prognostic favorable (3.08e-8)" "unprognostic (1.95e-1)" "unprognostic (3.91e-2)" "unprognostic (6.54e-3)" "unprognostic (7.36e-3)" 214.3 71.9 50.1 51.6 51.5 107.7 95.8 62.1 50.8 98.5 62.6 84.3 54.7 55.8 131.5 73.2 70.4 99.1 573.9 49.9 66.2 204.0 60.9 190.3 65.9 66.0 59.4 50.1 49.6 117.8 83.6 121.5 69.0 84.3 87.0 79.5 66.6 77.9 66.0 52.6 56.8 61.7 66.3 85.4 61.2 18.2 59.1 26.0 325.5 70.7 57.7 112.8 54.8 102.2 48.1 66.4 25.9 63.3 392.8 46.0 39.2 48.2 67.3 23.0 41.0 35.4 66.1 30.2 60.3 54.5 159.1 62.6 15.0 25.3 28.4 22.9 38.9 134.4 46.7 96.7 107.5 27.7 140.7 100.2 86.5 33.6 22.9 53.2 6.2 50.6 24.3 61.7 67.9 46.0 15.5 48.3 30.3 105.2 40.5 19.4 25.5 41.4 112.0 273.0 40.4 55.0 43.8 145.2 590.5 35.6 47.9 31.3 43.6 30.3 43.1 55.8 23.7 75.5 184.3 22.0 89.5 61.3 24.6 285.2 455.4 318.7 47.6 676.4 43.1 83.9 35.5 36.1 175.1 65.9 40.8 37.9 627.6 60.5 731.4 33.0 43.7 407.2 50.1 51.5 62.1 50.8 49.9 66.2 66.0 59.4 69.0 66.3 59.1 102.2 98.5 317.3 405.0 36.9 92.8 58.6 83.3 103.7 35.3 97.5 105.6 87.8 777.0 100.1 280.9 450.6 45.9 177.4 67.6 83.4 60.7 150.6 2.8 85.7 51.5 79.7 98.1 106.3 49.8 104.1 65.2 122.0 43.3 133.8 257.0 49.3 134.6 50.6 921.2 77.4 53.2 99.3 201.4 564.3 89.9 6.0 88.6 524.6 318.4 56.2 259.2 532.6 53.5 49.8 49.0 64.7 125.5 105.7 87.4 87.8 77.6 304.2 147.3 88.0 177.5 74.5 157.0 14.0 63.6 84.9 64.2 148.2 61.3 53.4 89.7 139.9 NAT1 AAC1 ENSG00000171428 "N-acetyltransferase 1" P18440 8 18170477-18223689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 24.2;Paneth cells: 32.7;Respiratory ciliated cells: 32.0" "Cancer enriched" "Detected in all" 14 "breast cancer: 47.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB017782, HPA043704" Approved NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB017782: , HPA043704: AB_2678625" "unprognostic (1.31e-1)" "unprognostic (1.05e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (8.25e-2)" "unprognostic (5.20e-2)" "unprognostic (6.53e-2)" "unprognostic (6.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.37e-2)" "unprognostic (9.51e-2)" "unprognostic (6.60e-2)" "unprognostic (7.44e-2)" "unprognostic (2.30e-1)" "unprognostic (3.28e-2)" "unprognostic (8.15e-2)" 3.6 1.5 0.5 5.4 0.7 3.2 5.9 0.8 0.9 6.5 0.8 14.2 11.7 2.4 15.2 2.5 4.4 3.6 1.8 0.5 0.7 5.7 10.4 3.5 6.0 1.2 0.7 2.9 1.8 1.1 1.0 4.1 0.8 7.3 12.8 0.3 1.9 2.9 0.4 2.4 8.9 3.6 0.8 4.1 4.9 1.8 0.8 4.6 2.1 1.5 6.7 4.5 1.3 1.0 22.6 2.7 2.5 3.3 6.3 6.3 5.3 8.0 8.5 8.8 10.2 4.0 4.7 11.0 6.2 5.2 8.1 3.6 4.5 5.4 8.9 10.3 2.3 7.6 3.0 3.0 6.0 3.3 9.7 5.2 6.5 6.0 0.5 2.2 7.9 9.3 6.6 2.9 10.0 4.0 9.8 10.3 2.4 17.8 3.4 4.9 2.5 4.3 9.3 12.6 1.3 1.7 0.3 9.5 5.5 5.2 7.7 9.7 8.5 5.3 3.1 8.0 1.3 2.0 4.0 9.3 4.6 7.5 2.4 5.4 4.6 9.4 3.3 5.3 2.4 4.4 3.4 3.4 6.1 3.9 3.2 3.9 8.2 6.3 5.4 3.5 6.3 2.7 0.5 0.7 0.8 0.9 0.5 0.7 1.2 0.7 0.8 0.8 0.8 1.0 4.6 0.0 3.6 0.7 4.7 0.4 0.8 9.1 1.2 0.0 3.5 1.9 1.6 0.0 11.3 5.5 0.0 5.9 2.3 24.2 1.9 5.7 10.8 3.9 3.2 3.0 3.6 0.8 0.8 6.9 7.7 2.1 3.6 2.8 2.5 1.1 2.2 12.7 7.2 0.0 0.2 10.7 8.2 6.3 2.6 2.2 4.1 5.3 3.6 1.9 4.9 2.5 4.1 0.0 0.5 5.8 32.7 5.7 2.6 2.3 12.7 16.6 32.0 0.0 0.0 0.7 3.4 4.2 0.6 2.2 0.6 10.9 4.1 3.2 8.4 2.5 NAT2 AAC2 ENSG00000156006 "N-acetyltransferase 2" P11245 8 18391282-18401218 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "intestine: 33.5;liver: 128.6" "Group enriched" "Detected in some" 4 "Distal enterocytes: 14.8;Hepatocytes: 59.0;Paneth cells: 15.9;Proximal enterocytes: 36.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0;liver cancer: 4.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.0;RT4: 1.6;SCLC-21H: 2.2;SK-BR-3: 1.4" HPA043704 Uncertain NA NA "Cluster 85: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 2: Hepatocytes - Metabolism" "HPA043704: AB_2678625" "unprognostic (2.74e-3)" "unprognostic (4.03e-1)" "prognostic favorable (4.61e-5)" "unprognostic (1.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.52e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (1.33e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-3)" "unprognostic (1.02e-1)" "unprognostic (3.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" 0.1 0.1 0.2 1.6 0.2 0.0 1.1 0.2 0.6 0.5 0.1 15.0 33.5 0.9 0.7 0.1 0.2 0.2 0.2 0.2 0.2 1.9 128.6 0.2 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.6 0.1 0.4 13.2 0.0 0.0 0.5 0.0 0.0 25.6 1.6 0.2 1.3 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.0 1.0 1.6 2.2 0.0 0.0 1.4 0.0 0.1 0.3 0.2 0.5 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.6 0.2 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 1.0 0.0 14.8 5.9 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.4 59.0 0.2 0.0 0.0 7.4 0.0 1.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.9 2.6 0.0 0.0 36.0 0.8 0.3 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 4.4 0.1 0.8 6.7 0.1 PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4" "Cell type enhanced" "Detected in many" "Astrocytes: 558.3;Early spermatids: 686.7;Excitatory neurons: 284.7;Oligodendrocyte precursor cells: 488.1;Oligodendrocytes: 584.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.8;hTERT-RPE1: 48.0;LHCN-M2: 47.3;U-87 MG: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA002455: AB_2666597" "unprognostic (3.87e-2)" "unprognostic (2.52e-2)" "prognostic favorable (7.55e-4)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.56e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (7.27e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-3)" "unprognostic (2.13e-1)" "unprognostic (7.18e-3)" "unprognostic (3.71e-2)" "unprognostic (8.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" 2.4 17.8 24.8 3.1 46.2 1.2 5.9 62.4 46.1 11.9 0.0 6.7 4.8 8.8 3.8 5.3 2.5 7.4 27.5 51.9 4.0 1.9 18.9 4.6 2.5 3.3 10.0 18.0 9.9 18.4 7.3 6.6 1.8 3.9 7.3 19.9 4.1 5.8 1.3 4.4 5.0 5.8 0.0 10.4 9.8 16.4 7.8 2.2 6.1 2.3 3.4 5.8 4.3 17.2 11.0 5.7 25.0 0.1 8.8 53.8 1.3 5.7 8.9 5.1 10.5 3.3 4.3 6.5 3.6 23.8 22.3 0.9 7.3 10.1 9.7 0.0 6.6 0.6 4.6 0.5 15.9 0.2 0.4 14.2 6.2 28.2 4.9 48.0 6.8 1.6 0.8 4.9 47.3 3.7 0.0 1.2 4.9 9.6 14.7 5.2 21.4 3.0 12.7 14.0 10.7 11.8 2.5 1.1 3.8 5.4 0.3 2.6 28.0 15.7 10.8 37.5 5.1 0.4 0.7 14.8 49.5 2.7 5.4 0.7 0.2 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.3 0.3 0.2 0.1 0.4 0.1 24.8 46.2 62.4 46.1 51.9 4.0 3.3 10.0 1.8 0.0 7.8 17.2 8.1 3.2 2.7 558.3 3.3 21.9 13.7 26.4 13.6 191.9 14.4 10.7 119.2 7.2 23.9 9.2 118.9 3.2 0.1 48.5 1.9 13.5 686.7 12.5 69.9 8.2 6.1 0.0 284.7 8.7 1.7 44.3 43.8 6.6 0.0 87.2 4.2 42.9 13.1 18.5 121.6 20.0 44.7 16.0 25.9 217.9 33.2 9.0 1.8 148.9 59.7 78.0 0.0 488.1 584.6 27.0 13.5 53.8 0.1 11.2 20.3 0.3 41.0 52.0 13.1 29.3 17.7 16.5 17.7 32.4 9.9 1.1 1.1 114.9 17.2 23.7 SH2D4A "FLJ20967, PPP1R38, SH2A" ENSG00000104611 "SH2 domain containing 4A" Q9H788 8 19313693-19396218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.7;Pancreatic endocrine cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 181.7;OE19: 102.5;U-2197: 130.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001871, HPA001919" Enhanced Enhanced Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "HPA001871: AB_1079949, HPA001919: AB_1079947" "unprognostic (9.08e-2)" "unprognostic (8.40e-3)" "unprognostic (4.04e-3)" "unprognostic (2.72e-3)" "unprognostic (3.51e-2)" "unprognostic (4.07e-3)" "unprognostic (2.25e-1)" "unprognostic (2.68e-1)" "unprognostic (1.67e-1)" "unprognostic (2.70e-2)" "unprognostic (8.84e-3)" "unprognostic (2.81e-1)" "prognostic favorable (6.02e-8)" "unprognostic (1.67e-2)" "unprognostic (2.18e-1)" "unprognostic (3.51e-3)" "unprognostic (4.11e-2)" 5.0 8.8 1.6 4.1 1.4 0.1 6.2 1.2 2.0 13.6 1.9 13.6 12.7 4.0 1.7 20.4 9.1 11.1 3.1 1.6 1.5 12.6 39.1 15.8 1.0 1.6 1.6 36.9 13.1 18.2 1.4 17.7 1.9 7.4 10.8 9.6 24.0 10.1 0.6 7.2 12.6 2.0 1.3 3.3 29.9 2.2 1.5 1.3 16.8 1.6 7.4 18.3 10.5 2.0 60.5 67.3 0.2 0.1 6.5 8.0 44.9 73.9 36.6 70.7 68.3 55.7 53.4 0.0 17.4 181.7 11.2 30.5 2.7 20.0 73.6 0.2 1.0 0.0 40.7 8.6 38.3 1.6 0.3 7.8 24.5 48.4 8.8 42.5 0.3 0.0 0.1 0.1 12.0 27.2 0.1 0.7 15.8 102.5 25.4 0.1 0.0 19.5 19.5 62.6 4.1 0.1 66.0 70.6 0.2 10.4 13.3 5.3 1.2 22.9 0.1 130.8 22.4 0.0 0.7 0.2 23.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.2 0.0 1.8 0.1 0.0 0.0 0.1 0.0 1.6 1.4 1.2 2.0 1.6 1.5 1.6 1.6 1.9 1.3 1.5 2.0 8.5 64.1 33.9 6.5 0.9 1.5 15.0 22.2 5.2 2.2 9.4 5.6 2.0 34.3 26.2 46.0 27.1 87.7 0.3 20.1 43.0 50.3 25.3 30.9 6.0 5.4 3.0 0.0 1.5 67.0 69.4 11.7 67.8 34.4 1.3 43.3 2.5 45.5 37.7 1.7 1.0 24.8 54.9 8.5 1.6 53.5 6.2 6.3 0.0 1.9 0.6 3.5 0.0 11.1 0.3 99.1 8.3 11.3 0.4 14.6 20.5 10.9 46.9 36.2 19.7 3.0 6.5 0.5 2.8 31.9 2.6 30.6 1.0 52.0 26.3 31.2 CSGALNACT1 "ChGn, CSGalNAcT-1, FLJ11264" ENSG00000147408 "Chondroitin sulfate N-acetylgalactosaminyltransferase 1" Q8TDX6 8 19404161-19758029 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 494.3;Excitatory neurons: 144.4;Granulosa cells: 214.1;Microglial cells: 224.9;Oligodendrocyte precursor cells: 355.9" "Cancer enhanced" "Detected in all" "prostate cancer: 22.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 62.6" "Group enriched" "Detected in all" 5 "B-cells: 44.5;granulocytes: 24.9;T-cells: 62.6" "Cell line enhanced" "Detected in many" "A549: 57.8;BJ hTERT+: 32.3;GAMG: 22.9;RPTEC TERT1: 39.6;U-2197: 36.8;U-87 MG: 26.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068462 Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Golgi apparatus" "HPA068462: " "unprognostic (8.90e-2)" "unprognostic (1.57e-2)" "unprognostic (4.66e-2)" "unprognostic (2.58e-1)" "unprognostic (6.03e-2)" "unprognostic (3.17e-3)" "unprognostic (9.78e-2)" "unprognostic (7.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (8.22e-2)" "unprognostic (6.82e-2)" "unprognostic (1.22e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (1.46e-3)" "unprognostic (1.02e-2)" 19.4 12.5 20.3 8.8 15.7 11.1 7.4 4.8 18.3 18.0 0.7 4.7 3.5 7.0 5.4 31.2 11.8 16.1 35.8 16.3 11.5 6.0 2.8 11.7 7.6 6.3 11.2 57.0 7.9 11.4 3.0 38.8 7.6 31.8 2.5 2.5 6.8 9.8 5.8 4.8 4.7 12.3 6.7 8.7 6.9 2.8 8.9 11.7 86.7 11.0 8.8 23.4 8.1 10.7 2.1 57.8 0.5 0.0 9.3 2.1 7.9 1.4 32.3 0.3 0.3 3.1 1.0 0.0 0.3 0.0 22.9 0.7 0.0 0.0 0.4 7.5 0.4 0.2 16.2 1.9 4.1 0.0 0.1 0.9 1.6 0.7 0.3 0.4 11.6 0.2 0.0 0.1 0.1 2.6 2.9 0.2 0.3 8.3 1.7 0.3 0.1 0.0 39.6 1.6 0.2 0.3 17.2 6.9 2.4 1.5 0.1 0.4 1.0 1.1 1.3 36.8 0.9 0.3 0.0 0.0 26.0 3.4 11.4 0.1 2.9 24.9 5.6 0.1 0.6 44.5 25.7 8.5 2.8 15.9 44.6 11.6 15.6 8.4 0.4 4.2 62.6 11.7 20.3 15.7 4.8 18.3 16.3 11.5 6.3 11.2 7.6 6.7 8.9 10.7 33.3 3.2 1.1 494.3 27.3 4.5 7.4 0.2 0.6 0.3 4.1 0.8 45.8 0.0 0.9 12.9 10.4 1.9 6.2 0.0 1.9 5.7 6.9 7.5 1.2 38.5 3.0 3.2 144.4 1.7 14.6 20.9 2.0 2.0 0.0 214.1 26.7 0.2 15.8 18.5 76.5 0.0 16.2 27.4 6.5 7.4 5.3 14.1 12.4 224.9 3.5 1.0 6.2 355.9 4.6 3.1 0.0 12.0 21.3 21.8 0.0 0.1 1.5 1.0 6.6 2.1 12.0 0.7 0.1 0.5 3.1 8.3 9.6 77.0 0.1 2.8 INTS10 "C8orf35, FLJ10569, INT10" ENSG00000104613 "Integrator complex subunit 10" Q9NVR2 8 19817391-19852083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039129, HPA050570" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Nucleoplasm "HPA039129: AB_10794424, HPA050570: AB_2681180" "unprognostic (9.11e-2)" "unprognostic (8.41e-3)" "prognostic favorable (4.00e-4)" "prognostic favorable (1.22e-4)" "unprognostic (4.54e-2)" "unprognostic (9.79e-3)" "unprognostic (1.15e-1)" "unprognostic (1.14e-3)" "unprognostic (3.41e-1)" "unprognostic (1.38e-1)" "unprognostic (1.67e-2)" "unprognostic (2.62e-1)" "unprognostic (8.58e-3)" "unprognostic (1.34e-3)" "unprognostic (1.08e-1)" "unprognostic (2.34e-2)" "unprognostic (1.33e-1)" 27.7 24.0 42.2 24.6 44.1 34.3 29.1 44.2 57.6 27.5 40.3 28.5 26.6 22.5 20.3 26.6 38.7 21.5 21.7 44.4 43.2 29.9 47.6 24.2 30.5 43.0 42.3 25.3 42.6 28.3 18.7 23.0 42.9 29.2 27.3 37.2 30.4 20.0 25.6 31.8 24.1 26.1 42.1 22.7 25.0 15.2 43.7 29.2 43.7 18.6 33.2 24.6 18.0 45.1 40.0 57.3 32.5 42.1 48.7 53.3 41.5 29.5 50.6 40.3 38.4 33.6 19.7 113.9 47.9 33.1 43.9 42.3 39.5 38.5 44.8 22.4 40.0 51.7 62.6 63.2 35.0 45.2 34.2 42.3 58.9 29.8 46.5 24.8 40.2 65.4 66.3 88.2 28.4 33.9 86.7 53.4 42.6 92.9 32.2 43.7 35.9 73.1 52.8 60.7 32.2 26.1 41.1 51.0 37.1 29.1 26.2 43.6 29.2 25.5 35.0 59.1 39.5 24.7 30.5 81.5 51.4 64.4 41.1 10.0 23.7 14.5 19.6 21.4 30.8 26.5 25.6 25.2 30.9 21.7 28.1 25.1 7.7 27.7 18.6 27.1 31.8 20.2 42.2 44.1 44.2 57.6 44.4 43.2 43.0 42.3 42.9 42.1 43.7 45.1 25.5 16.0 51.1 74.4 40.3 37.6 40.9 29.3 43.3 60.2 28.3 20.3 22.5 37.1 39.1 20.2 52.1 33.7 41.5 22.9 35.2 43.6 53.9 78.8 23.1 33.0 20.4 27.3 88.8 40.0 49.2 34.1 25.5 33.4 35.5 63.6 35.3 61.0 42.4 70.7 61.0 34.3 22.4 34.0 25.5 31.9 34.8 35.6 17.8 37.5 37.8 33.9 45.3 80.9 74.9 33.1 27.4 35.0 48.6 53.4 33.9 37.5 70.0 99.0 13.1 29.1 32.5 8.3 32.3 50.8 45.0 22.3 40.6 41.2 42.0 32.7 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 SLC18A1 "CGAT, VAT1, VMAT1" ENSG00000036565 "Solute carrier family 18 member A1" P54219 8 20144855-20183206 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "adrenal gland: 25.1" "Cell type enriched" "Detected in some" 27 "Enteroendocrine cells: 139.0" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.8" "Region enriched" "Detected in single" 19 "midbrain: 3.9" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 19 "monocytes: 2.8" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA006877, HPA063797" Enhanced NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "HPA006877: AB_2667690, HPA063797: AB_2685125" "unprognostic (8.03e-4)" "unprognostic (1.02e-1)" "unprognostic (3.75e-3)" "unprognostic (3.50e-1)" "unprognostic (6.61e-2)" "unprognostic (3.09e-3)" "unprognostic (1.67e-1)" "unprognostic (2.16e-2)" "unprognostic (3.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-2)" "unprognostic (8.25e-2)" "unprognostic (4.41e-2)" "unprognostic (2.06e-1)" "unprognostic (1.05e-1)" 0.1 25.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 1.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 3.8 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 3.9 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 139.0 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.8;parathyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.6;Excitatory neurons: 26.2;Horizontal cells: 20.2;Melanocytes: 19.6;Rod photoreceptor cells: 18.5;Sertoli cells: 65.7;Smooth muscle cells: 15.4" "Cancer enhanced" "Detected in all" "melanoma: 59.2" "Group enriched" "Detected in many" 5 "amygdala: 13.1;basal ganglia: 11.6;cerebral cortex: 14.8;hippocampal formation: 14.5;white matter: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 19.7;SK-MEL-30: 75.0;U-698: 23.2;WM-115: 50.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 23.2;basal ganglia: 66.8;cerebral cortex: 45.5;hippocampal formation: 36.3;olfactory bulb: 26.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoli "HPA006294: AB_1079288, HPA022046: AB_1853455" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (6.27e-2)" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.41e-2)" "unprognostic (9.06e-3)" "unprognostic (6.81e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (9.28e-6)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (6.82e-3)" 3.7 1.7 13.1 1.5 11.6 0.1 3.0 0.0 14.8 2.0 0.0 1.3 0.5 2.9 0.9 5.3 1.6 3.5 5.0 14.5 0.6 4.7 0.7 7.0 1.1 0.0 0.1 1.2 1.5 54.2 2.2 6.5 0.3 2.8 0.4 3.5 1.4 1.1 1.9 4.6 0.9 2.5 0.0 0.5 1.4 7.5 2.3 1.9 2.7 2.0 0.5 2.3 1.7 9.2 0.1 0.0 9.7 8.3 0.0 0.0 1.2 5.0 0.1 4.3 3.7 0.3 0.1 11.1 3.5 3.1 1.6 0.2 0.5 0.2 2.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 1.7 0.9 0.1 1.8 0.0 0.6 0.0 11.7 0.0 0.1 14.4 0.0 19.7 0.1 12.2 0.0 0.0 0.0 15.6 0.0 2.7 0.4 14.8 12.9 0.0 0.0 75.0 8.2 0.1 0.4 0.0 5.1 3.5 0.1 1.5 0.1 0.1 23.2 0.1 1.1 50.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.1 11.6 0.0 14.8 14.5 0.6 0.0 0.1 0.3 0.0 2.3 9.2 3.9 0.0 0.0 1.6 0.0 1.3 0.8 1.0 17.6 1.8 0.3 11.3 4.6 0.0 0.1 0.0 4.2 7.1 0.4 0.0 1.9 0.0 0.5 0.6 1.3 3.2 0.0 0.0 26.2 0.0 2.3 2.4 0.0 0.5 0.0 3.5 0.0 0.0 0.9 20.2 2.9 0.0 2.0 0.0 0.0 0.8 1.2 0.2 19.6 1.9 0.0 0.9 0.0 6.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 18.5 65.7 1.1 15.4 0.2 1.1 7.3 0.1 0.8 1.4 2.5 0.0 0.0 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 DOK2 "Dok-2, p56dok-2" ENSG00000147443 "Docking protein 2" O60496 8 21908873-21913690 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 25.6;lymphoid tissue: 40.9" "Cell type enhanced" "Detected in many" "dendritic cells: 130.6;Hofbauer cells: 131.8;Kupffer cells: 171.8;Langerhans cells: 288.4;Macrophages: 181.5;NK-cells: 344.0;T-cells: 147.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1565.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 25.3;HEL: 54.3;HMC-1: 119.8;JURKAT: 22.3;THP-1: 43.1;U-937: 42.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB004379, HPA005507, HPA066571" Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Nucleoplasm, Nuclear bodies, Golgi apparatus" "CAB004379: AB_627449, HPA005507: , HPA066571: AB_2732749" "unprognostic (5.39e-2)" "unprognostic (8.84e-3)" "unprognostic (8.72e-3)" "unprognostic (1.74e-3)" "unprognostic (2.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.34e-1)" "unprognostic (7.22e-2)" "prognostic favorable (4.31e-4)" "unprognostic (2.22e-1)" "unprognostic (4.19e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.88e-1)" "unprognostic (1.24e-2)" "unprognostic (3.19e-1)" "unprognostic (2.80e-1)" 9.5 5.0 1.1 26.5 1.2 19.5 5.0 1.2 2.3 1.9 2.5 5.5 7.0 2.2 0.5 2.3 3.5 6.5 3.5 1.3 1.3 3.0 6.1 25.6 26.3 1.4 1.5 1.4 1.9 0.5 1.1 7.9 1.5 2.3 3.6 0.0 3.4 1.5 2.0 2.3 9.5 6.9 1.2 40.9 6.8 1.6 4.5 16.4 2.4 1.6 7.8 8.4 2.3 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 54.3 0.0 0.1 0.0 0.4 119.8 0.0 0.0 0.0 0.0 0.0 0.0 22.3 0.8 5.0 0.0 0.0 0.9 8.7 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.1 0.3 0.0 0.1 0.2 0.1 0.2 0.1 0.3 1.4 42.0 0.2 577.6 484.3 1565.6 398.3 624.0 184.5 14.5 274.3 304.8 421.9 6.6 151.0 185.9 37.2 307.6 580.7 7.6 597.2 810.3 1.1 1.2 1.2 2.3 1.3 1.3 1.4 1.5 1.5 1.2 4.5 1.5 2.0 3.2 18.1 0.0 13.2 11.5 0.6 0.0 0.0 0.0 1.2 1.8 2.1 0.0 1.3 3.7 0.0 0.7 130.6 0.3 0.0 0.1 0.2 0.2 0.5 2.8 0.0 10.5 0.1 0.0 1.0 2.6 3.1 0.4 36.3 0.1 5.7 1.1 131.8 0.0 0.0 0.2 0.0 171.8 288.4 0.6 0.3 181.5 19.6 0.0 74.8 0.0 344.0 0.0 0.0 0.0 0.0 0.0 15.4 0.2 0.0 0.7 1.5 0.0 0.0 0.6 2.5 0.2 4.3 0.7 8.5 1.0 147.4 0.0 0.2 0.8 XPO7 "KIAA0745, RANBP16" ENSG00000130227 "Exportin 7" Q9UIA9 8 21919662-22006585 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 169.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043727, HPA048153" Uncertain NA NA 53000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" "HPA043727: AB_2678638, HPA048153: AB_2680289" "unprognostic (6.30e-2)" "unprognostic (1.95e-2)" "prognostic favorable (2.29e-4)" "unprognostic (6.61e-3)" "unprognostic (1.81e-1)" "unprognostic (1.33e-2)" "unprognostic (1.17e-2)" "unprognostic (1.81e-1)" "unprognostic (1.18e-1)" "unprognostic (6.81e-3)" "unprognostic (9.66e-2)" "unprognostic (3.69e-2)" "unprognostic (2.76e-2)" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (1.69e-1)" "unprognostic (1.19e-1)" 20.0 21.8 25.1 21.9 27.2 61.9 26.6 24.5 25.7 26.5 24.7 24.7 15.9 30.7 28.5 26.5 30.5 20.3 31.3 27.9 23.2 40.3 19.2 22.5 26.8 19.7 20.7 39.7 21.7 43.4 19.9 31.8 20.3 21.3 28.3 45.0 20.6 24.7 33.2 28.0 17.7 28.6 22.4 23.2 23.6 41.0 24.3 33.4 35.5 40.5 31.2 23.9 21.6 28.4 47.8 83.2 60.7 43.9 49.9 43.3 47.9 46.2 54.3 67.2 60.4 63.6 29.1 78.0 51.5 57.6 61.0 45.5 87.9 66.2 117.8 23.7 44.7 87.5 67.9 46.9 34.0 42.3 63.9 34.0 45.9 67.1 64.0 48.8 65.5 69.1 106.0 61.0 49.9 36.8 105.6 39.4 78.3 81.2 33.0 60.5 78.3 40.9 44.3 98.0 36.7 57.9 43.8 45.3 46.4 61.2 41.2 34.7 42.9 35.0 44.5 50.3 47.0 21.4 25.9 83.0 53.5 50.9 63.1 6.4 3.4 2.6 5.1 4.6 4.3 4.5 4.5 3.9 5.1 3.2 3.4 4.3 1.6 3.4 4.3 1.8 4.9 3.9 25.1 27.2 24.5 25.7 27.9 23.2 19.7 20.7 20.3 22.4 24.3 28.4 14.8 22.4 11.4 37.5 14.6 14.3 6.3 9.0 10.2 31.8 11.8 10.7 38.1 15.7 13.5 18.4 14.6 11.5 12.0 11.2 3.9 10.3 70.5 12.0 12.0 12.4 20.9 169.5 65.8 11.2 13.4 13.1 19.9 11.3 7.6 32.1 13.6 14.1 14.4 50.5 68.8 12.0 8.2 23.9 11.3 39.7 15.5 16.8 10.6 37.5 17.3 15.3 11.3 70.4 70.9 10.7 6.5 17.7 15.7 10.3 7.8 15.3 9.8 23.5 13.1 14.9 13.2 21.6 21.4 16.0 12.1 5.6 9.4 13.2 12.8 8.5 NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.0;parathyroid gland: 39.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 29.4;Cone photoreceptor cells: 20.9;Excitatory neurons: 21.3;Inhibitory neurons: 21.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 10.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 17.7;HEL: 14.5;Hep G2: 32.4;JURKAT: 9.5;THP-1: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nucleoli" "HPA041070: AB_2677285" "unprognostic (1.40e-2)" "unprognostic (3.30e-2)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.61e-1)" "unprognostic (3.03e-2)" "unprognostic (5.30e-3)" "unprognostic (1.01e-1)" "prognostic favorable (9.02e-4)" "unprognostic (2.23e-1)" "prognostic favorable (3.18e-6)" "unprognostic (8.05e-3)" "unprognostic (2.89e-1)" "unprognostic (1.42e-1)" "unprognostic (1.30e-1)" 0.6 18.4 11.0 0.1 16.9 1.2 2.1 7.4 40.0 4.9 2.2 1.1 2.2 5.0 0.9 1.0 3.2 1.9 2.3 12.4 9.2 6.6 1.6 1.8 0.6 7.5 7.6 1.5 11.0 39.2 18.5 0.5 10.0 6.6 1.0 5.7 2.7 1.4 0.3 2.2 1.2 3.6 2.3 12.5 1.9 5.1 7.1 2.9 25.3 0.3 0.4 2.0 2.3 13.5 3.9 0.5 0.2 0.2 0.9 0.0 1.5 0.5 0.5 2.4 4.9 1.6 3.6 0.0 1.1 0.0 0.2 17.7 0.5 0.0 1.4 0.1 0.5 14.5 1.0 32.4 3.1 1.9 1.3 0.5 2.3 0.0 0.3 3.7 0.0 9.5 0.5 0.0 0.1 0.0 0.2 3.9 0.7 6.4 0.4 0.3 1.4 0.8 5.6 0.1 3.8 0.2 0.0 0.1 4.6 0.0 0.7 11.2 0.0 0.0 0.3 0.6 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.2 0.0 0.7 0.0 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 11.0 16.9 7.4 40.0 12.4 9.2 7.5 7.6 10.0 2.3 7.1 13.5 0.1 0.0 1.1 1.0 0.7 0.1 9.7 3.7 0.6 29.4 3.1 5.2 2.1 5.7 8.8 0.0 20.9 0.1 0.5 0.6 3.9 9.4 15.1 1.1 0.3 0.6 11.4 0.4 21.3 8.0 0.2 1.7 1.5 1.1 0.0 1.4 2.5 0.5 4.6 6.7 21.9 2.1 2.0 0.0 0.3 14.4 0.6 0.9 10.6 1.9 1.0 0.9 0.0 2.5 1.6 4.3 0.8 0.4 0.6 3.4 0.5 14.6 7.7 4.2 0.0 0.4 1.6 0.5 0.9 1.1 1.1 0.3 2.7 7.6 1.2 5.8 FGF17 FGF-13 ENSG00000158815 "Fibroblast growth factor 17" O60258 8 22042398-22048809 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.7;choroid plexus: 10.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 9.3;Cone photoreceptor cells: 14.6;Excitatory neurons: 10.6;Inhibitory neurons: 13.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6;testis cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.1;RPMI-8226: 1.8" "Region enriched" "Detected in single" 4 "basal ganglia: 2.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" HPA052600 Uncertain "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA052600: AB_2681881" "unprognostic (3.45e-2)" "unprognostic (1.64e-2)" "unprognostic (3.03e-2)" "unprognostic (1.34e-1)" "unprognostic (1.33e-2)" "unprognostic (3.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (7.92e-5)" "unprognostic (6.85e-2)" "unprognostic (2.58e-4)" "unprognostic (6.55e-3)" "unprognostic (7.18e-2)" "unprognostic (2.41e-1)" "unprognostic (1.95e-3)" 0.5 3.9 15.1 0.0 14.9 0.1 0.4 22.0 25.7 3.0 10.6 0.4 0.0 1.1 0.1 0.2 1.5 0.2 0.5 14.3 14.2 1.4 0.4 0.7 0.0 11.9 12.2 1.5 1.2 0.8 5.1 0.1 12.2 2.7 0.0 1.1 0.7 0.1 0.0 0.5 0.4 0.3 10.9 3.6 0.5 0.7 14.2 0.4 4.8 0.0 0.0 0.6 1.3 14.4 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 14.9 22.0 25.7 14.3 14.2 11.9 12.2 12.2 10.9 14.2 14.4 0.2 0.0 0.0 2.3 0.0 0.0 0.3 0.1 0.0 9.3 0.2 0.4 1.1 0.0 0.2 0.0 14.6 0.1 0.0 0.1 0.0 0.1 1.8 0.0 0.1 0.1 0.0 0.0 10.6 0.2 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.1 1.7 13.1 0.0 0.0 0.0 0.0 0.3 0.3 0.0 1.8 1.0 0.0 0.6 0.0 2.0 2.4 0.1 0.0 1.2 0.1 0.2 0.0 0.0 0.2 1.3 0.0 0.3 0.2 0.2 0.5 0.0 0.0 0.3 0.1 0.4 0.0 0.1 DMTN "DMT, EPB49" ENSG00000158856 "Dematin actin binding protein" Q08495 8 22048995-22082527 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 192.5" "Cell type enriched" "Detected in many" 5 "Erythroid cells: 248.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 3.8;memory CD8 T-cell: 1.6;naive CD4 T-cell: 1.5;naive CD8 T-cell: 1.5;neutrophil: 1.2;T-reg: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;T-cells: 3.8" "Cell line enhanced" "Detected in many" "A549: 68.9;HEL: 225.9;Hep G2: 63.9;HMC-1: 65.6;OE19: 67.3;RPTEC TERT1: 87.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024290, HPA058487" Uncertain NA NA 2400000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "HPA024290: AB_1847601, HPA058487: " "unprognostic (6.74e-2)" "unprognostic (1.51e-1)" "unprognostic (3.48e-2)" "unprognostic (1.24e-3)" "prognostic unfavorable (7.92e-5)" "unprognostic (2.88e-1)" "unprognostic (3.85e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-2)" "unprognostic (2.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.97e-1)" "prognostic favorable (3.85e-9)" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (1.86e-1)" "unprognostic (8.07e-2)" 35.7 29.8 104.2 6.1 134.6 136.6 21.8 0.0 192.5 13.5 0.0 33.1 9.2 15.3 14.4 18.9 30.4 13.5 71.5 142.1 36.9 67.5 28.2 20.1 3.4 27.0 14.0 3.4 29.6 54.9 109.6 7.4 27.1 25.0 15.2 23.0 22.9 20.4 66.4 24.3 14.0 14.0 0.0 19.3 23.8 11.7 32.4 3.0 39.1 41.4 3.7 12.9 12.4 90.5 44.1 68.9 0.5 1.4 1.1 0.3 5.4 4.6 4.3 14.5 4.3 29.9 26.7 0.4 43.8 0.8 0.9 14.8 2.1 2.7 6.5 0.4 13.0 225.9 5.3 63.9 1.3 0.1 65.6 0.7 29.3 0.2 0.3 8.5 14.7 2.0 21.7 2.2 0.1 18.9 5.7 0.5 1.8 67.3 6.1 0.0 0.6 3.1 87.2 12.3 15.6 21.8 7.3 0.9 3.2 3.5 11.2 2.2 26.1 0.0 22.0 0.3 24.0 0.1 0.2 0.7 0.3 0.2 15.4 0.0 0.1 0.2 1.7 0.0 1.7 0.0 3.8 1.6 0.1 0.0 1.5 1.5 1.2 0.0 0.0 0.3 3.3 9.3 104.2 134.6 0.0 192.5 142.1 36.9 27.0 14.0 27.1 0.0 32.4 90.5 9.3 3.2 10.7 10.7 1.5 2.3 4.0 3.9 1.2 34.6 9.9 5.7 37.8 0.0 5.1 7.3 12.5 0.1 2.7 15.3 19.6 11.4 12.7 11.2 1.7 10.2 20.5 248.6 45.7 11.4 1.7 2.4 7.7 12.7 0.0 4.1 3.9 15.8 0.5 28.6 29.7 8.7 0.0 1.0 1.6 7.7 0.3 44.5 14.2 5.6 1.3 2.6 0.0 1.5 4.3 18.2 10.0 2.6 1.4 3.7 1.8 29.6 9.3 7.3 0.0 1.4 5.7 1.4 2.4 3.8 5.7 0.1 6.4 0.3 13.3 4.8 FAM160B2 "FLJ21801, RAI16" ENSG00000158863 "Family with sequence similarity 160 member B2" Q86V87 8 22089150-22104911 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025040 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA025040: AB_1856049" "unprognostic (3.45e-1)" "unprognostic (2.08e-3)" "unprognostic (1.60e-1)" "unprognostic (8.85e-3)" "unprognostic (2.28e-2)" "prognostic favorable (4.56e-4)" "unprognostic (2.35e-2)" "unprognostic (4.82e-2)" "unprognostic (1.01e-1)" "unprognostic (2.90e-2)" "unprognostic (8.38e-3)" "unprognostic (7.67e-3)" "unprognostic (3.38e-2)" "unprognostic (6.30e-2)" "unprognostic (1.08e-2)" "unprognostic (1.25e-1)" "unprognostic (2.75e-3)" 13.9 11.5 4.5 3.9 4.1 3.6 15.8 3.5 5.5 12.5 3.5 16.2 5.8 12.3 4.9 13.6 12.7 5.6 21.7 3.6 3.5 14.6 10.5 10.6 6.3 4.8 4.2 10.0 22.3 8.2 13.2 5.2 4.1 14.6 2.5 3.0 16.7 10.6 17.7 14.0 13.5 6.9 3.7 11.4 17.4 6.1 4.8 4.2 15.4 7.2 2.2 16.2 12.0 4.6 4.4 8.7 4.3 6.8 9.2 8.1 7.8 8.0 13.6 8.6 5.8 3.9 4.7 4.9 7.7 19.7 7.8 6.3 3.3 9.3 1.9 4.1 4.2 7.3 2.8 2.2 12.4 1.9 5.7 13.6 6.9 6.6 4.4 8.9 9.1 8.8 4.6 3.3 8.3 8.0 5.0 2.9 2.1 8.0 3.8 5.1 3.7 2.5 7.4 8.9 1.8 5.8 4.6 6.6 5.2 4.5 4.3 3.2 10.3 8.4 7.2 8.0 4.6 3.5 0.9 0.9 9.0 3.1 9.7 0.0 0.4 0.1 0.8 0.2 0.5 0.7 0.5 0.6 0.2 0.5 0.4 0.7 0.0 0.4 0.4 0.2 0.0 0.7 4.5 4.1 3.5 5.5 3.6 3.5 4.8 4.2 4.1 3.7 4.8 4.6 16.4 12.8 17.2 17.0 11.6 5.9 10.1 9.9 12.5 22.0 16.4 13.5 26.1 12.8 8.8 12.9 27.1 8.5 10.1 15.5 0.0 9.7 3.7 8.9 14.5 16.8 13.2 1.3 12.3 15.0 15.5 12.5 23.0 11.8 7.0 19.1 16.8 13.6 7.4 23.5 12.0 10.8 0.0 9.4 4.7 2.5 10.8 8.2 1.8 8.4 4.4 8.7 9.2 12.1 11.0 17.1 17.1 5.7 6.3 15.1 14.7 5.0 10.8 23.8 0.0 11.0 14.7 1.5 7.0 16.1 7.5 14.9 11.2 9.6 9.9 12.4 NUDT18 "FLJ22494, MTH3" ENSG00000275074 "Nudix hydrolase 18" Q6ZVK8 8 22106874-22109419 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028581, HPA030125" Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus" "HPA028581: AB_10601381, HPA030125: AB_2673324" "unprognostic (9.90e-3)" "prognostic favorable (1.43e-4)" "unprognostic (4.88e-3)" "prognostic favorable (2.49e-6)" "unprognostic (1.29e-2)" "unprognostic (6.82e-3)" "unprognostic (1.20e-1)" "unprognostic (1.54e-2)" "unprognostic (5.30e-2)" "unprognostic (1.67e-1)" "prognostic favorable (2.47e-4)" "unprognostic (1.43e-1)" "prognostic favorable (8.30e-4)" "unprognostic (3.59e-3)" "unprognostic (1.05e-1)" "unprognostic (6.84e-2)" "unprognostic (2.32e-1)" 7.4 6.4 5.1 4.8 5.2 4.4 6.7 5.4 5.5 4.9 4.3 5.7 6.5 5.4 12.9 8.0 5.3 4.2 4.8 5.4 4.8 6.8 5.6 6.1 8.8 5.3 4.8 2.3 17.0 2.7 9.1 2.7 5.7 7.8 4.7 1.2 8.5 4.6 2.3 7.1 7.6 3.6 4.4 10.4 8.9 7.7 5.4 6.8 8.2 1.2 6.3 5.7 5.5 4.6 8.1 16.8 0.5 3.6 12.4 4.6 9.0 4.8 12.6 6.1 7.0 4.0 6.3 6.0 7.5 5.7 15.5 13.8 2.3 7.7 2.0 7.5 2.3 5.1 4.9 3.9 8.3 1.7 15.2 8.5 7.2 2.4 6.4 7.9 7.7 13.0 3.8 9.9 6.0 8.6 6.9 4.6 0.9 4.8 4.1 3.0 1.5 6.5 9.0 7.1 1.8 2.8 3.3 4.0 4.2 3.7 9.4 8.3 6.4 4.0 2.2 5.4 2.5 4.4 0.5 1.9 7.0 4.5 9.8 0.0 1.5 3.0 2.2 1.6 2.1 1.4 1.8 1.3 1.0 2.0 2.0 1.1 0.3 4.0 1.3 1.9 0.7 0.9 5.1 5.2 5.4 5.5 5.4 4.8 5.3 4.8 5.7 4.4 5.4 4.6 5.6 3.2 2.2 1.0 7.3 2.0 3.4 5.2 1.2 3.3 5.9 4.6 1.9 8.6 3.0 5.5 0.0 6.7 6.8 12.5 5.9 9.5 14.6 5.9 2.4 4.7 3.0 5.2 1.6 13.6 9.6 5.9 6.1 4.1 0.0 6.3 5.7 4.0 14.5 3.3 1.7 10.9 2.0 16.8 1.3 15.1 3.1 9.0 5.4 2.8 15.3 4.1 19.6 0.5 1.6 10.1 14.6 3.4 6.2 4.6 41.2 13.6 7.0 1.2 0.0 3.1 3.7 3.5 2.7 6.3 1.8 3.1 7.9 5.3 7.0 2.3 HR "ALUNC, AU" ENSG00000168453 "HR lysine demethylase and nuclear receptor corepressor" O43593 8 22114419-22133384 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Oxidoreductase" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.9;skin 1: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 91.4;Cone photoreceptor cells: 33.3;Distal enterocytes: 27.5;Gastric mucus-secreting cells: 26.5;Paneth cells: 31.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 21.2;HaCaT: 81.7;OE19: 39.9;SiHa: 28.8;T-47d: 30.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054888 Supported Nucleoplasm NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA054888: AB_2682630" "unprognostic (9.11e-2)" "unprognostic (2.12e-2)" "unprognostic (7.32e-2)" "unprognostic (4.68e-3)" "unprognostic (6.49e-2)" "unprognostic (2.80e-1)" "unprognostic (1.53e-2)" "unprognostic (2.45e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" "unprognostic (1.75e-1)" "unprognostic (2.27e-2)" "unprognostic (8.00e-3)" "unprognostic (1.81e-1)" "unprognostic (2.32e-1)" "unprognostic (2.28e-2)" 2.4 1.0 4.3 1.8 6.7 0.0 2.7 7.8 14.5 3.8 0.0 9.0 4.8 1.6 0.1 20.9 1.1 1.3 2.3 3.1 4.8 0.6 0.4 0.8 0.3 11.3 9.0 0.6 0.5 0.0 2.7 0.1 12.0 3.8 3.2 1.8 5.1 4.2 0.7 52.7 4.7 1.5 2.4 0.5 7.7 5.3 8.8 0.6 4.3 0.9 1.2 3.0 11.7 11.5 1.9 21.2 0.0 0.0 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.0 2.6 0.0 20.7 1.5 1.0 81.7 0.0 2.0 0.0 0.0 0.0 0.0 17.8 0.1 4.7 0.0 0.1 4.1 12.9 0.0 1.4 1.3 0.0 2.1 0.0 0.2 0.0 12.7 1.5 0.3 0.0 39.9 16.3 1.9 0.0 0.5 0.3 5.7 1.0 4.7 28.8 6.4 6.5 0.3 30.0 0.0 0.0 0.4 17.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 6.7 7.8 14.5 3.1 4.8 11.3 9.0 12.0 2.4 8.8 11.5 1.9 0.0 0.0 1.3 0.0 12.0 4.5 4.3 10.8 91.4 4.0 3.9 2.7 0.0 1.4 1.8 33.3 0.1 0.1 27.5 0.0 0.1 0.3 1.6 1.2 0.6 7.8 0.0 8.7 0.7 0.2 2.1 26.5 2.1 0.0 0.3 1.8 0.3 0.0 10.1 3.9 8.1 0.0 0.0 2.1 1.9 3.4 0.1 21.4 0.0 0.0 3.2 0.0 2.0 9.2 0.3 31.2 7.2 0.0 3.0 11.0 0.1 1.3 8.8 0.0 5.8 3.3 0.1 0.3 15.5 17.8 0.8 0.3 0.2 19.5 6.8 AC105206.4 ENSG00000288677 "Novel protein" 8 22130604-22130708 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 2.4;salivary gland: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 5.1;U-2 OS: 3.4" NA NA "Cluster 2: Karpas-707 - Immune response" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 REEP4 "C8orf20, FLJ22246, FLJ22277, PP432, Yip2c" ENSG00000168476 "Receptor accessory protein 4" Q9H6H4 8 22138020-22141951 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 89.3;skin 1: 91.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042683 Approved Supported "Endoplasmic reticulum" No Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" "Endoplasmic reticulum" "HPA042683: AB_2571730" "unprognostic (2.38e-1)" "unprognostic (9.96e-3)" "unprognostic (3.35e-2)" "unprognostic (2.38e-2)" "unprognostic (3.41e-2)" "unprognostic (7.75e-2)" "prognostic unfavorable (4.14e-5)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" "unprognostic (7.15e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (2.88e-5)" "unprognostic (5.72e-2)" "unprognostic (1.06e-1)" "unprognostic (2.25e-1)" "unprognostic (6.65e-2)" 13.0 8.4 7.0 12.5 8.7 28.4 11.6 8.7 9.7 27.9 7.6 23.8 11.0 9.4 2.1 89.3 11.1 5.6 8.0 6.8 8.2 9.2 12.3 18.0 11.2 10.8 8.5 7.4 12.9 5.0 10.9 14.6 10.5 13.6 10.8 2.1 21.8 6.5 4.1 91.0 16.9 5.9 9.0 33.2 18.0 42.7 9.5 9.9 14.8 2.6 10.2 19.6 49.0 11.5 42.2 79.7 24.9 39.7 10.5 10.6 47.9 36.7 19.2 44.6 40.2 46.7 38.8 53.0 46.8 18.4 38.5 100.3 29.6 59.3 21.9 28.2 37.4 57.4 41.2 46.9 11.8 25.8 77.9 9.8 110.3 33.3 27.5 13.9 27.1 58.1 44.5 158.7 22.6 60.6 63.7 88.9 37.4 58.0 53.3 37.0 22.5 101.8 19.9 40.0 21.7 40.1 30.0 31.7 52.7 16.5 64.3 35.9 30.5 29.2 50.1 66.6 50.3 40.0 33.5 34.6 32.6 54.7 59.1 49.8 54.8 64.1 24.3 53.6 19.6 10.5 21.1 21.1 42.7 4.9 9.7 13.1 15.5 26.3 37.0 16.9 15.4 27.6 7.0 8.7 8.7 9.7 6.8 8.2 10.8 8.5 10.5 9.0 9.5 11.5 6.8 3.2 9.2 4.9 7.9 28.0 15.1 45.5 15.4 6.5 5.8 5.7 1.8 7.2 21.9 12.9 2.1 54.0 13.8 27.3 0.0 21.9 16.0 3.8 4.9 9.2 17.4 48.2 0.7 15.0 50.4 8.1 21.9 5.9 10.2 14.0 15.4 6.6 55.4 0.0 0.6 33.0 22.4 38.8 21.5 9.4 9.0 26.1 3.6 10.3 16.5 1.8 10.3 1.0 2.6 25.6 34.7 8.2 19.3 19.0 19.2 1.9 8.1 1.5 13.1 2.3 9.7 61.0 17.9 41.1 39.2 94.1 13.5 8.9 31.1 24.5 LGI3 ENSG00000168481 "Leucine rich repeat LGI family member 3" Q8N145 8 22146830-22157084 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 112.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 22.2;Excitatory neurons: 17.7;Inhibitory neurons: 23.7;Melanocytes: 40.9;Oligodendrocytes: 58.4" "Group enriched" "Detected in many" 5 "glioma: 4.7;melanoma: 14.3;thyroid cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;SCLC-21H: 1.6;SK-MEL-30: 1.6;WM-115: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024826 Approved Cytosol "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA024826: AB_10601131" "unprognostic (4.41e-2)" "unprognostic (1.78e-1)" "unprognostic (3.28e-1)" "unprognostic (8.11e-3)" "unprognostic (1.14e-1)" "unprognostic (7.45e-2)" "unprognostic (3.38e-1)" "unprognostic (2.43e-2)" "unprognostic (9.64e-2)" "unprognostic (1.64e-2)" "unprognostic (6.25e-3)" "unprognostic (1.26e-2)" "unprognostic (5.59e-5)" "unprognostic (1.36e-2)" "unprognostic (9.41e-2)" "unprognostic (4.80e-2)" "unprognostic (4.14e-2)" 0.3 3.4 44.2 0.1 79.7 0.1 0.2 81.1 84.6 2.9 5.2 0.8 0.3 1.2 0.3 6.5 1.6 0.1 2.2 43.4 70.4 0.4 0.1 15.9 0.0 85.8 72.4 0.2 0.8 0.3 2.8 0.0 90.7 1.3 0.1 3.9 1.7 2.8 0.2 15.0 0.5 0.6 57.1 0.1 0.9 0.8 86.3 0.3 13.0 0.1 0.3 0.2 2.5 112.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.6 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 79.7 81.1 84.6 43.4 70.4 85.8 72.4 90.7 57.1 86.3 112.6 0.0 0.0 22.2 2.0 0.0 2.3 0.0 0.0 0.0 2.7 0.1 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.8 0.0 17.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.4 0.0 0.3 0.1 40.9 2.8 0.0 1.2 0.0 6.6 58.4 0.1 0.0 7.2 0.0 0.0 0.0 0.8 0.0 2.9 0.0 0.0 0.6 0.1 0.1 1.4 0.6 0.0 0.0 0.9 0.0 0.0 SFTPC "BRICD6, PSP-C, SFTP2, SMDP2, SP-C" ENSG00000168484 "Surfactant protein C" P11686 8 22156913-22164479 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Gaseous exchange" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 795 "lung: 18462.2" "Cell type enriched" "Detected in some" 12 "Alveolar cells type 2: 107013.9" "Cancer enriched" "Detected in some" 218 "lung cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 9.5;NB-4: 12.4;SCLC-21H: 5.1;U-2197: 24.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010928 Enhanced "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" "HPA010928: AB_1857425" "unprognostic (1.84e-1)" "unprognostic (1.96e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-2)" 2.6 23.2 10.3 10.3 12.1 0.0 0.9 10.8 15.8 1.6 8.3 1.3 0.0 0.4 0.3 0.9 0.4 0.0 2.8 10.2 10.6 1.0 2.8 18462.2 0.0 11.9 11.2 21.5 1.7 0.0 1.1 4.7 10.8 3.0 0.0 0.0 0.8 8.9 2.0 3.1 2.3 0.0 10.3 14.0 6.4 2.8 11.4 0.0 4.3 0.1 0.2 0.1 0.9 15.3 0.0 0.1 0.0 0.0 0.5 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 12.4 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 5.1 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.1 24.4 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 12.1 10.8 15.8 10.2 10.6 11.9 11.2 10.8 10.3 11.4 15.3 0.0 8535.2 107013.9 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 1416.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.0 0.0 67.8 0.0 0.0 0.9 0.0 0.0 174.6 0.0 0.0 986.5 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.3 30.4 0.0 106.6 23.2 0.0 0.0 0.0 0.0 0.5 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 339.6 0.0 6.6 0.0 0.3 0.1 0.1 0.0 0.6 0.0 163.4 0.4 0.0 0.1 BMP1 "BMP-1, PCOLC" ENSG00000168487 "Bone morphogenetic protein 1" P13497 8 22165140-22212326 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor, Hydrolase, Metalloprotease, Protease" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 69.3;Endometrial stromal cells: 52.8;Smooth muscle cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014572 Enhanced "Secreted to extracellular matrix" NA NA 9200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA014572: AB_1845390" "unprognostic (1.24e-1)" "unprognostic (8.01e-2)" "unprognostic (3.75e-2)" "unprognostic (5.89e-2)" "unprognostic (1.34e-2)" "unprognostic (6.76e-2)" "unprognostic (9.53e-2)" "unprognostic (2.64e-3)" "unprognostic (1.66e-1)" "unprognostic (9.75e-3)" "unprognostic (7.05e-3)" "unprognostic (3.14e-2)" "prognostic unfavorable (3.37e-9)" "unprognostic (2.11e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-3)" "unprognostic (3.34e-2)" 11.7 17.4 3.8 6.3 4.6 1.4 9.0 4.7 4.4 15.6 4.9 8.1 4.8 12.7 3.9 7.0 11.8 9.8 5.9 4.3 3.9 7.7 14.7 8.3 1.7 5.0 4.1 5.9 4.4 3.4 3.4 27.3 4.1 9.6 5.3 0.6 3.7 6.1 3.4 6.2 5.9 14.4 4.3 5.0 4.3 2.4 4.2 1.5 10.0 3.1 1.8 10.4 10.3 4.4 15.2 20.4 7.4 30.2 47.8 41.8 23.2 54.1 50.1 33.8 27.6 5.1 27.4 3.7 32.0 56.9 18.9 51.2 5.1 27.8 6.5 3.6 6.9 6.7 24.5 7.9 31.7 2.9 14.3 49.8 26.5 25.2 11.4 78.3 31.4 5.2 7.1 10.6 19.6 4.6 1.4 3.0 4.7 17.0 8.3 6.4 8.2 15.2 26.7 4.1 2.8 10.6 52.5 3.1 13.4 20.4 5.0 8.3 41.4 17.0 18.4 32.3 23.9 4.0 2.2 0.6 23.8 10.1 28.0 0.0 0.4 0.0 0.6 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.1 3.8 4.6 4.7 4.4 4.3 3.9 5.0 4.1 4.1 4.3 4.2 4.4 12.5 6.4 69.3 5.5 0.8 6.2 5.2 22.6 4.0 2.6 5.0 6.1 4.9 2.8 6.7 5.5 0.0 3.3 3.2 31.9 0.0 25.1 0.7 3.1 52.8 14.1 3.0 0.8 3.5 8.2 9.5 28.7 1.1 5.7 15.2 13.9 14.6 20.1 4.3 1.7 2.7 6.2 0.0 3.4 6.1 1.1 10.2 5.4 10.6 4.7 1.0 2.2 3.1 6.6 6.7 15.3 18.6 10.9 2.8 4.7 13.2 4.1 2.2 1.1 26.3 6.4 43.7 1.5 4.0 6.5 5.3 24.4 3.3 34.2 10.7 8.0 PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 217.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.9;Basal squamous epithelial cells: 14.8;Excitatory neurons: 48.5;Inhibitory neurons: 15.4" "Cancer enhanced" "Detected in many" "glioma: 6.3;thyroid cancer: 6.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 9.3;SH-SY5Y: 3.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 101.1;basal ganglia: 300.5;cerebellum: 251.7;cerebral cortex: 256.5;hippocampal formation: 296.8" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Nucleoplasm "HPA068030: AB_2685944, HPA069318: AB_2686117" "unprognostic (1.19e-2)" "unprognostic (2.33e-2)" "unprognostic (3.06e-2)" "unprognostic (9.22e-3)" "unprognostic (2.07e-3)" "unprognostic (2.35e-1)" "unprognostic (1.59e-1)" "unprognostic (2.80e-1)" "unprognostic (3.01e-2)" "unprognostic (7.44e-3)" "unprognostic (2.36e-1)" "unprognostic (4.05e-2)" "unprognostic (4.44e-5)" "unprognostic (8.62e-4)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (4.09e-3)" 11.3 33.1 106.0 1.5 183.9 0.0 9.3 98.1 217.1 11.6 0.0 14.1 1.3 14.5 2.8 9.8 25.6 6.7 5.2 210.3 21.9 9.4 0.7 2.5 0.2 63.7 11.5 7.1 1.6 0.2 35.7 2.5 58.1 11.9 0.6 2.2 1.8 5.9 0.9 55.8 5.1 8.1 2.0 11.5 3.7 10.7 30.7 0.2 3.9 0.3 0.2 12.1 15.1 137.4 0.6 1.6 0.3 0.0 0.2 0.5 0.8 0.2 0.9 0.2 0.2 0.1 1.4 0.0 1.5 0.5 1.0 2.6 0.0 0.4 0.0 0.0 0.1 0.0 3.0 1.0 1.1 0.0 0.0 0.6 0.0 0.6 0.0 2.5 1.7 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.6 0.5 0.2 0.0 0.2 9.3 0.0 0.0 2.9 3.5 2.0 0.0 2.4 0.2 0.0 0.2 0.7 0.0 1.4 1.1 0.5 0.6 0.1 0.0 1.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 106.0 183.9 98.1 217.1 210.3 21.9 63.7 11.5 58.1 2.0 30.7 137.4 1.1 0.0 0.0 7.2 0.0 18.9 5.5 5.6 14.8 1.5 0.7 1.3 1.4 1.5 1.9 3.7 0.0 0.1 0.1 0.2 0.0 0.2 0.8 0.4 3.6 1.5 0.0 0.0 48.5 2.1 0.4 5.6 0.5 0.2 0.0 0.0 1.4 1.0 0.2 0.0 15.4 0.7 0.0 0.0 1.4 1.8 3.1 0.1 1.8 5.6 0.0 0.6 0.0 7.5 5.8 0.8 0.0 3.8 0.0 1.3 2.6 3.5 0.3 1.1 0.0 0.2 8.0 0.4 0.4 8.2 10.9 2.2 0.2 0.1 0.1 5.0 POLR3D "BN51T, C53, RPC4, TSBN51" ENSG00000168495 "RNA polymerase III subunit D" P05423 8 22245133-22254601 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061331, HPA067875, HPA068461, HPA069089" Supported Enhanced Nucleoplasm NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "HPA061331: AB_2684480, HPA067875: AB_2685912, HPA068461: AB_2685993, HPA069089: AB_2686081" "unprognostic (2.33e-1)" "unprognostic (2.27e-1)" "unprognostic (9.38e-3)" "unprognostic (9.33e-3)" "unprognostic (1.24e-1)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.02e-1)" "unprognostic (2.19e-2)" "unprognostic (3.27e-1)" "unprognostic (8.03e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (9.15e-6)" "unprognostic (1.15e-1)" "unprognostic (3.13e-1)" "unprognostic (6.93e-2)" "prognostic unfavorable (2.12e-4)" 15.0 11.9 3.4 4.4 3.3 6.5 10.6 3.0 3.9 14.1 3.8 11.3 2.5 10.4 3.3 15.2 11.3 4.1 14.1 3.0 3.6 11.7 10.0 11.1 4.7 3.7 3.6 14.9 17.5 4.0 13.7 6.6 3.6 12.8 4.5 4.0 10.6 3.8 32.8 11.2 8.6 5.8 3.5 11.4 10.6 19.3 3.9 3.4 10.6 8.3 4.3 15.1 14.4 4.3 5.1 10.7 11.0 7.8 10.0 16.6 11.3 18.9 9.1 10.7 8.7 10.5 3.6 27.8 10.2 12.5 8.9 9.1 16.9 9.2 11.0 6.9 9.4 20.7 10.5 11.2 13.6 5.0 9.5 13.8 12.9 13.4 21.8 13.1 8.9 14.9 28.9 9.5 8.7 7.2 22.2 10.4 18.9 13.0 9.0 14.7 12.2 18.0 6.1 6.0 7.8 24.2 8.5 5.9 17.7 11.9 5.4 8.0 13.0 9.4 9.1 18.8 11.4 17.0 22.7 18.9 9.2 10.1 14.0 0.1 1.4 0.3 1.8 1.1 2.5 2.4 2.3 2.6 1.6 2.2 3.0 1.9 0.1 2.9 1.6 3.5 1.8 1.3 3.4 3.3 3.0 3.9 3.0 3.6 3.7 3.6 3.6 3.5 3.9 4.3 15.0 9.6 6.5 4.6 15.8 19.5 43.6 21.2 13.6 12.8 15.2 14.5 10.9 4.3 13.3 11.0 16.7 16.2 18.5 6.9 11.7 20.2 42.7 11.6 37.7 15.6 21.5 10.3 2.4 11.8 33.2 21.3 12.8 14.8 18.4 18.7 11.7 3.8 13.7 3.3 2.8 19.1 12.2 8.8 8.2 40.5 15.8 8.6 8.8 1.0 13.4 4.5 14.4 2.5 3.5 22.5 6.7 12.8 20.5 52.3 6.7 12.6 11.2 12.2 19.7 22.1 21.3 44.2 52.0 12.1 19.2 27.0 15.0 25.1 12.3 41.8 PIWIL2 "CT80, FLJ10351, HILI, Mili" ENSG00000197181 "Piwi like RNA-mediated gene silencing 2" Q8TC59 8 22275316-22357568 "Predicted intracellular proteins" "Biological rhythms, Differentiation, Meiosis, Oogenesis, RNA-mediated gene silencing, Spermatogenesis, Translation regulation" "Developmental protein, Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 28.8" "Group enriched" "Detected in many" 4 "Spermatocytes: 62.4;Spermatogonia: 48.9" "Cancer enriched" "Detected in some" 6 "testis cancer: 6.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "NTERA-2: 38.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "unprognostic (1.91e-2)" "unprognostic (1.77e-2)" "unprognostic (6.51e-2)" "unprognostic (2.18e-1)" "unprognostic (8.29e-2)" "unprognostic (3.58e-3)" "unprognostic (2.60e-1)" "unprognostic (2.37e-1)" "unprognostic (7.59e-2)" "unprognostic (6.68e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.16e-7)" "unprognostic (1.27e-1)" "unprognostic (7.83e-2)" "unprognostic (1.05e-3)" "unprognostic (2.61e-2)" 1.1 0.2 0.7 0.5 0.8 0.2 1.1 0.8 0.7 1.2 0.4 0.9 6.0 0.9 0.3 0.2 1.2 0.1 0.6 1.1 1.4 0.3 1.1 0.3 0.3 0.5 0.9 1.8 2.4 0.0 1.5 0.1 1.0 0.8 0.9 0.9 0.8 0.5 2.5 0.7 1.9 0.5 0.3 0.3 1.4 28.8 2.0 0.1 0.5 1.1 0.2 0.8 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 38.1 0.3 0.0 0.0 0.1 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.8 0.7 1.1 1.4 0.5 0.9 1.0 0.3 2.0 0.9 1.0 6.4 3.0 3.9 0.2 1.0 1.0 0.3 1.8 6.6 0.6 0.6 1.2 0.0 0.0 1.8 8.4 0.1 0.4 5.9 0.0 0.1 4.5 5.8 1.8 0.8 0.0 0.0 2.5 1.6 0.4 2.3 5.1 8.9 1.3 0.7 0.7 3.6 0.1 0.0 3.4 5.1 0.0 0.3 0.7 5.9 2.8 0.7 1.8 5.6 0.8 0.6 1.0 2.5 4.2 1.3 3.2 2.2 0.1 1.5 13.2 0.4 2.3 3.0 0.0 3.5 1.6 62.4 48.9 0.1 1.6 0.3 0.6 1.0 7.1 0.9 SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 266.7;Hepatocytes: 611.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 321.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" 63.5 72.4 13.0 35.5 11.0 1.4 39.8 11.9 13.1 17.3 39.7 48.2 142.2 30.2 6.2 11.6 25.9 32.0 76.7 14.5 22.9 30.8 551.3 23.9 7.6 43.0 30.4 27.7 252.7 12.9 21.5 19.0 25.7 22.3 50.3 18.6 21.8 18.7 43.0 20.0 84.9 33.0 13.3 8.1 80.5 26.5 25.3 6.0 87.7 17.4 6.9 56.0 14.5 14.8 51.8 68.3 18.4 37.6 65.1 54.7 40.1 72.8 321.0 111.3 173.5 226.9 47.9 51.1 39.9 86.1 288.9 55.6 92.8 91.1 181.9 53.1 49.2 40.8 51.0 230.7 154.3 28.5 43.2 58.4 72.6 198.0 136.9 56.3 50.5 36.5 36.2 51.2 57.3 24.0 43.4 18.2 113.4 81.9 49.8 60.1 34.9 110.8 40.8 22.3 31.3 48.7 74.3 31.3 151.4 39.7 25.1 39.4 28.0 137.3 69.2 87.4 75.7 29.2 28.7 66.9 194.3 37.7 81.9 0.0 0.4 2.1 6.7 0.1 7.2 4.0 3.8 5.0 1.5 1.9 4.3 5.9 0.1 2.7 0.1 0.7 3.4 3.4 13.0 11.0 11.9 13.1 14.5 22.9 43.0 30.4 25.7 13.3 25.3 14.8 12.4 3.2 7.7 11.4 9.1 33.3 11.5 10.8 18.8 7.8 20.3 16.6 66.6 41.5 3.8 7.3 2.1 0.4 3.6 91.6 1.9 47.6 0.5 136.1 58.3 32.2 33.4 10.5 26.2 74.7 2.7 58.8 47.9 266.7 0.0 20.8 29.6 611.4 1.8 48.8 24.6 60.6 6.1 15.4 25.8 3.2 23.9 2.9 44.4 6.5 2.7 5.2 2.1 9.0 3.9 47.3 39.1 41.8 13.5 26.5 75.6 24.6 1.1 8.2 0.0 47.1 32.2 0.7 3.0 4.1 21.0 0.5 7.4 14.7 43.5 9.4 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favorable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 28.5 11.9 11.8 16.5 11.8 26.5 20.8 17.7 15.3 18.1 31.1 16.6 9.1 14.5 10.6 16.9 15.6 15.7 34.5 11.3 10.8 12.9 12.4 21.5 33.0 12.1 11.0 14.0 14.3 18.4 11.7 19.3 12.2 14.4 10.3 77.9 14.0 8.2 89.4 13.6 15.4 15.5 10.0 22.4 14.6 56.0 13.1 15.0 16.6 54.2 26.9 17.0 16.4 14.8 12.2 8.8 7.7 9.4 19.8 24.4 11.2 16.5 28.9 23.9 26.5 5.1 7.5 45.7 19.7 25.6 40.0 8.4 17.9 16.5 30.5 26.3 9.5 9.8 10.5 14.7 26.8 7.1 15.6 15.0 22.3 16.2 16.5 25.6 21.1 22.0 19.6 58.8 27.2 5.7 16.8 11.7 5.6 12.5 12.0 54.0 18.1 15.2 22.4 11.3 5.4 12.7 12.3 7.4 17.4 14.4 4.9 11.8 22.8 37.1 7.9 56.7 12.9 29.3 38.5 48.3 19.6 9.3 25.1 5.4 2.7 10.7 16.6 3.2 12.7 26.3 19.0 23.6 5.1 21.3 18.1 14.9 0.6 19.2 4.7 6.2 17.2 7.1 11.8 11.8 17.7 15.3 11.3 10.8 12.1 11.0 12.2 10.0 13.1 14.8 27.2 6.4 5.1 49.6 74.7 16.6 21.3 32.6 12.0 12.8 10.0 6.0 8.0 14.3 14.0 7.3 47.9 18.0 50.3 6.7 7.9 15.0 145.8 6.5 12.7 24.2 10.3 10.8 78.9 21.0 23.8 25.1 6.6 14.6 3.8 3.9 23.6 7.8 13.1 3.3 83.6 2.5 38.7 10.8 24.6 22.6 22.4 19.3 28.4 76.8 30.4 13.1 59.8 99.5 64.8 21.1 7.4 21.4 96.8 26.3 10.6 11.6 7.8 50.5 32.9 19.5 23.3 131.8 29.6 17.1 11.4 14.1 53.4 4.8 6.3 25.5 SORBS3 "SCAM-1, SH3D4, vinexin" ENSG00000120896 "Sorbin and SH3 domain containing 3" O60504 8 22544986-22575788 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.4;Late spermatids: 505.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015849 Approved Uncertain "Focal adhesion sites,Cytosol" NA NA 7700 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Focal adhesion sites" "HPA015849: AB_1857365" "unprognostic (6.15e-3)" "unprognostic (2.09e-2)" "unprognostic (2.34e-1)" "unprognostic (3.90e-3)" "unprognostic (1.72e-1)" "unprognostic (9.30e-2)" "unprognostic (2.51e-2)" "unprognostic (2.44e-2)" "unprognostic (5.83e-3)" "unprognostic (1.70e-1)" "prognostic favorable (4.88e-4)" "unprognostic (4.21e-2)" "unprognostic (3.08e-3)" "unprognostic (7.41e-2)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.53e-5)" 173.3 65.3 59.3 26.2 59.7 5.1 129.0 67.6 72.6 156.9 49.9 105.2 29.9 124.0 23.6 65.5 118.8 38.7 105.8 53.0 55.3 84.8 121.2 111.9 21.1 85.0 60.6 125.6 49.3 35.7 73.3 66.6 65.6 127.2 34.9 11.4 88.7 48.5 64.7 106.8 71.2 53.7 61.7 80.0 63.7 128.2 65.7 7.6 93.8 37.3 13.4 103.5 133.9 57.6 83.0 101.8 54.6 61.9 86.4 114.4 55.7 83.0 127.8 95.0 58.8 103.6 36.2 0.7 55.3 130.1 38.3 69.7 82.5 75.7 48.9 58.1 36.2 6.9 58.3 48.4 98.2 0.8 0.5 72.6 55.6 33.3 48.4 105.2 74.6 42.7 18.4 2.6 68.4 32.8 7.1 2.4 19.3 14.1 42.5 79.0 36.8 7.7 43.7 15.8 3.1 48.9 40.4 9.8 52.7 56.8 16.7 29.2 116.9 83.8 59.8 61.9 59.3 1.7 2.5 11.5 49.0 19.4 58.3 0.0 2.5 0.6 11.4 4.7 23.4 0.8 12.6 13.4 8.1 1.3 12.7 7.6 0.5 5.8 1.1 2.7 0.6 5.2 59.3 59.7 67.6 72.6 53.0 55.3 85.0 60.6 65.6 61.7 65.7 57.6 89.6 19.2 7.2 27.1 5.8 29.2 24.6 23.3 39.9 2.7 29.0 27.8 12.2 31.5 18.3 12.9 0.0 24.1 4.7 53.5 9.8 21.3 169.4 10.9 39.5 51.9 14.6 2.1 3.8 19.2 30.5 48.8 8.6 20.5 17.2 19.3 79.9 49.5 35.3 5.0 4.5 35.2 8.2 39.0 31.5 505.8 61.2 23.8 24.9 13.1 5.7 21.9 3.1 19.6 7.6 26.2 53.2 58.6 3.7 38.8 65.1 26.0 10.7 3.5 59.2 23.1 84.1 7.0 8.0 25.3 21.3 20.5 19.7 7.1 31.3 23.7 PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 793.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 429.2" "Low region specificity" "Detected in many" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Actin filaments, Focal adhesion sites" "HPA003880: AB_1855149" "unprognostic (1.04e-1)" "unprognostic (3.53e-2)" "unprognostic (1.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-3)" "unprognostic (9.33e-2)" "unprognostic (3.69e-2)" "unprognostic (4.55e-2)" "unprognostic (1.79e-2)" "unprognostic (1.22e-3)" "unprognostic (1.52e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.37e-7)" "unprognostic (6.14e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.08e-3)" 66.0 31.6 40.6 31.9 42.2 23.7 51.0 51.0 56.6 85.1 42.6 86.9 60.9 80.2 9.8 131.4 56.0 52.8 51.4 36.9 43.9 77.7 59.4 88.8 54.4 56.6 52.9 49.6 53.7 9.8 35.3 40.5 59.4 45.5 11.2 2.0 48.6 30.9 201.9 153.1 64.3 23.2 49.9 232.0 38.8 12.2 49.9 20.4 27.4 60.9 24.4 57.5 91.7 54.8 90.3 54.5 36.2 63.9 69.9 118.5 40.9 139.1 102.4 97.6 98.5 62.4 14.7 36.9 38.4 126.4 18.1 44.7 20.5 95.0 19.0 0.1 14.1 11.6 35.2 46.1 88.2 13.0 85.9 127.2 11.6 48.2 13.2 76.8 54.2 20.2 3.3 23.4 67.4 46.5 16.7 15.4 29.8 37.8 5.5 13.3 6.9 3.9 17.3 18.3 11.3 26.9 29.1 78.1 128.7 21.3 27.5 25.8 68.2 105.7 108.6 127.9 64.8 0.4 0.8 12.5 109.0 51.3 79.6 78.2 48.0 162.3 47.0 64.4 42.2 25.0 35.5 46.9 38.4 27.6 23.8 35.4 101.6 28.1 63.8 24.7 40.7 34.6 40.6 42.2 51.0 56.6 36.9 43.9 56.6 52.9 59.4 49.9 49.9 54.8 85.8 76.9 13.1 5.5 45.0 95.1 12.9 48.1 39.9 3.0 34.0 42.5 10.2 18.6 34.2 18.4 0.0 73.1 70.9 92.0 15.6 24.9 1.0 8.8 94.0 48.7 1.2 10.5 3.2 26.1 115.1 98.9 7.7 13.8 27.3 25.7 86.4 49.4 59.0 3.3 2.3 12.6 20.3 59.1 73.8 3.4 132.0 37.9 48.0 8.4 42.5 33.1 122.6 7.1 3.9 93.2 126.1 218.2 6.8 52.7 217.6 146.3 5.2 3.6 59.2 27.1 108.3 0.7 6.3 39.7 100.7 793.0 71.6 21.0 15.0 30.6 AC037459.1 ENSG00000248235 "Novel protein" 8 22589274-22602084 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SH-SY5Y: 1.9;U-2 OS: 1.9;U-2197: 3.7;U-87 MG: 2.0" HPA024667 Uncertain NA NA "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "HPA024667: AB_1845783" "unprognostic (3.72e-2)" "unprognostic (5.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.01e-1)" "unprognostic (7.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.96e-1)" "unprognostic (2.29e-2)" "unprognostic (9.64e-2)" "unprognostic (1.67e-1)" "unprognostic (4.64e-3)" "unprognostic (2.29e-1)" "unprognostic (2.55e-4)" "unprognostic (1.48e-1)" "unprognostic (2.28e-2)" "unprognostic (2.28e-1)" "unprognostic (8.23e-3)" 0.7 0.4 0.3 0.8 0.3 0.0 0.2 0.8 0.8 0.6 0.4 0.5 0.4 0.5 0.0 0.3 0.2 0.3 0.2 0.2 0.3 0.3 0.2 0.7 0.7 0.7 0.4 0.4 0.0 0.0 0.1 0.3 0.7 0.3 0.0 0.0 0.8 0.0 1.4 0.7 1.7 0.3 0.3 2.6 0.5 0.0 0.4 0.2 0.2 0.1 0.0 0.3 0.5 0.6 0.1 0.7 0.3 1.6 0.0 1.5 0.2 1.0 1.3 0.5 1.1 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.2 0.2 0.3 0.0 0.5 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.7 0.9 1.5 0.1 0.6 0.3 0.0 0.9 1.9 3.7 0.1 0.0 0.0 0.1 2.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.8 0.8 0.2 0.3 0.7 0.4 0.7 0.3 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C8orf58 FLJ34715 ENSG00000241852 "Chromosome 8 open reading frame 58" Q8NAV2 8 22599599-22604150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 28.1;Extravillous trophoblasts: 30.4;Sertoli cells: 26.3;Syncytiotrophoblasts: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.2" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024667, HPA028286" Uncertain Approved "Nuclear bodies" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" "HPA024667: AB_1845783, HPA028286: AB_1845784" "unprognostic (8.88e-3)" "unprognostic (4.58e-2)" "unprognostic (1.99e-1)" "unprognostic (1.69e-2)" "unprognostic (6.72e-2)" "unprognostic (9.68e-2)" "unprognostic (2.60e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (8.70e-2)" "unprognostic (2.40e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.58e-6)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (5.20e-2)" 11.1 7.1 8.8 4.3 8.3 4.5 10.8 13.5 9.9 10.6 8.5 7.7 3.5 9.2 4.9 9.8 8.9 7.2 9.9 8.4 8.9 13.3 7.9 10.6 5.5 9.5 8.4 9.3 6.2 4.9 5.5 16.6 8.9 8.3 3.2 5.9 7.1 5.5 9.0 13.6 7.2 4.8 8.7 25.7 6.3 16.5 8.9 3.5 8.1 4.8 3.5 8.6 9.9 8.6 7.7 11.4 30.8 18.2 8.3 9.5 8.4 16.9 14.2 20.9 15.0 2.2 6.4 1.5 8.0 18.7 14.2 7.5 5.6 15.9 13.4 2.3 2.6 4.5 12.0 1.2 14.5 1.6 6.7 13.7 13.5 12.4 7.8 18.7 12.2 5.9 2.8 2.2 16.8 5.5 3.4 8.4 18.8 6.3 7.5 5.6 7.7 1.8 12.8 7.0 3.2 10.0 8.3 5.9 20.0 31.8 5.6 3.6 17.0 22.7 18.1 15.9 15.7 2.7 1.8 1.5 11.7 3.3 18.6 0.0 0.2 1.2 0.1 0.5 0.1 0.4 0.1 0.3 0.1 0.4 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.1 8.8 8.3 13.5 9.9 8.4 8.9 9.5 8.4 8.9 8.7 8.9 8.6 9.8 3.2 2.0 3.9 5.0 10.3 3.8 7.0 2.8 2.9 4.2 5.0 2.4 0.0 4.9 0.0 0.0 28.1 3.6 3.4 0.0 11.5 1.2 1.4 6.4 12.1 4.2 0.8 1.0 6.7 30.4 6.1 2.0 3.2 1.3 5.4 15.7 0.8 9.5 1.7 1.1 1.7 6.1 3.1 5.4 2.3 8.7 2.9 3.6 1.9 7.9 6.5 1.0 1.0 0.3 12.5 3.3 6.4 2.8 5.1 3.9 2.3 2.4 4.8 26.3 3.1 6.7 1.8 2.9 4.1 9.7 55.8 3.8 4.6 2.2 2.8 CCAR2 "DBC-1, DBC1, KIAA1967, NET35" ENSG00000158941 "Cell cycle and apoptosis regulator 2" Q8N163 8 22604632-22621514 "Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, DNA damage, mRNA processing, mRNA splicing, Transcription, Transcription regulation, Wnt signaling pathway" "Activator, Metalloenzyme inhibitor, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019907, HPA019943, CAB072827, CAB072828" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA 19000 "Cluster 39: Non-specific - mRNA processing" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Nuclear bodies" "CAB072827: , CAB072828: , HPA019907: AB_1852452, HPA019943: AB_1852454" "unprognostic (3.42e-2)" "unprognostic (5.78e-3)" "unprognostic (2.46e-3)" "unprognostic (1.33e-2)" "unprognostic (6.87e-2)" "unprognostic (2.23e-2)" "unprognostic (5.13e-2)" "unprognostic (8.56e-2)" "unprognostic (2.97e-1)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (1.54e-2)" "prognostic favorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (2.46e-1)" "unprognostic (7.54e-2)" "unprognostic (1.77e-1)" 64.1 68.3 39.2 75.4 44.2 145.5 64.4 40.2 52.4 65.6 45.6 68.5 52.1 75.0 33.0 63.4 67.9 59.7 52.0 47.0 33.8 54.8 41.1 61.4 86.7 36.9 42.3 74.6 56.4 59.8 65.1 54.0 38.6 61.1 45.6 59.8 61.5 46.9 101.4 89.0 69.3 44.9 34.7 85.6 60.0 89.4 39.6 96.0 60.6 43.5 74.3 65.4 57.6 47.9 133.7 242.8 230.8 120.8 89.5 74.7 154.0 127.7 124.9 184.3 163.9 219.5 107.4 218.6 156.4 140.5 169.6 163.2 214.5 151.9 132.9 89.2 128.2 259.1 189.5 172.8 82.9 143.6 212.0 77.8 133.1 147.0 90.0 106.4 134.4 194.4 276.2 134.8 138.0 157.5 435.0 150.5 337.6 143.2 88.1 286.7 190.7 116.8 95.2 311.7 115.1 267.6 143.7 163.0 112.6 110.7 148.8 133.2 219.3 135.8 178.4 165.3 171.1 98.5 134.0 261.4 152.7 123.4 215.7 25.9 16.2 23.5 34.8 26.6 29.4 18.7 26.5 26.6 16.6 17.5 25.7 28.4 5.7 19.9 35.6 15.5 32.6 25.8 39.2 44.2 40.2 52.4 47.0 33.8 36.9 42.3 38.6 34.7 39.6 47.9 14.4 16.0 4.2 11.1 14.1 13.9 9.5 12.2 17.6 12.9 13.5 13.1 7.5 15.7 9.4 16.5 16.7 27.3 19.4 24.1 9.8 18.1 4.7 14.1 12.3 13.1 22.2 16.4 12.5 18.0 22.2 12.8 18.8 14.3 8.8 20.2 11.7 12.0 15.7 10.1 11.9 19.6 14.2 11.9 8.5 7.3 14.9 11.0 12.4 10.3 11.2 15.9 20.6 11.1 10.3 23.6 10.4 12.0 14.8 11.7 14.4 9.4 19.5 12.9 19.7 12.4 12.2 30.0 24.1 16.9 15.3 23.7 19.3 23.5 21.7 10.5 BIN3 ENSG00000147439 "Bridging integrator 3" Q9NQY0 8 22620418-22669148 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Septation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 94.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023769 Approved NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "HPA023769: AB_1845361" "unprognostic (4.93e-3)" "unprognostic (4.42e-2)" "unprognostic (6.44e-3)" "unprognostic (1.44e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (7.36e-2)" "unprognostic (1.68e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-2)" "unprognostic (1.81e-1)" "unprognostic (3.79e-1)" "unprognostic (2.53e-2)" "unprognostic (2.20e-3)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-1)" 18.6 28.4 13.4 8.5 14.1 40.3 17.6 13.2 16.3 12.4 14.4 11.4 6.8 9.6 9.4 15.8 15.1 9.5 11.5 14.0 13.6 21.0 14.0 11.6 10.4 14.1 13.2 10.4 9.7 12.5 12.6 8.4 13.8 15.5 9.9 7.7 11.6 9.4 9.2 13.9 11.1 8.0 12.8 13.3 12.6 10.4 13.5 13.3 13.2 4.4 10.9 13.5 12.9 13.7 20.6 17.5 7.7 16.6 19.9 18.4 8.6 18.2 31.0 28.4 23.2 7.2 7.9 16.6 8.0 20.0 19.9 22.7 14.9 19.0 19.4 12.6 10.1 13.8 9.0 13.6 16.7 14.3 14.8 19.0 22.2 20.9 11.1 18.0 18.4 9.7 27.5 10.2 14.8 10.0 22.8 31.7 14.6 26.9 7.6 11.4 8.2 8.1 28.4 16.2 4.0 8.8 8.7 6.4 94.2 10.3 6.2 12.7 17.7 8.8 10.8 18.1 13.7 6.8 6.1 15.1 25.1 10.3 58.5 56.3 34.2 78.3 29.0 33.9 30.0 25.8 29.5 21.9 27.5 29.1 28.9 23.5 94.9 36.4 26.1 24.9 41.0 36.9 13.4 14.1 13.2 16.3 14.0 13.6 14.1 13.2 13.8 12.8 13.5 13.7 31.7 9.6 13.0 9.1 16.5 9.8 30.9 32.9 5.2 14.0 11.5 10.0 1.1 18.6 17.2 14.7 41.7 42.8 14.7 24.0 15.6 25.1 28.5 26.7 15.3 21.0 19.8 14.3 13.3 27.6 22.5 14.0 21.4 28.4 31.7 13.6 17.2 6.1 20.2 25.2 9.8 22.1 34.6 9.6 8.7 4.9 18.3 13.0 19.6 8.4 18.6 69.3 32.0 4.0 7.2 41.7 26.1 12.0 8.5 23.4 16.7 13.9 34.1 33.8 13.1 25.4 14.6 18.0 14.0 5.4 11.5 79.4 15.0 24.4 18.2 41.2 EGR3 PILOT ENSG00000179388 "Early growth response 3" Q06889 8 22687659-22693480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;skin 1: 45.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 284.3;Glandular and luminal cells: 116.6;granulocytes: 108.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 47.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HMC-1: 9.5;MCF7: 31.9;SK-MEL-30: 22.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 19.3;basal ganglia: 52.5;cerebral cortex: 47.8;hippocampal formation: 41.3;olfactory bulb: 33.7" "HPA006206, CAB009373" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB009373: AB_2097202, HPA006206: AB_10602491" "prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "unprognostic (4.07e-2)" "unprognostic (1.00e-1)" "unprognostic (6.44e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.48e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.11e-2)" "unprognostic (4.72e-2)" "unprognostic (2.35e-2)" "unprognostic (1.07e-2)" 29.0 24.5 7.7 19.0 9.9 10.1 10.3 0.6 47.2 9.5 0.0 4.6 1.5 5.6 0.4 5.9 17.3 30.0 12.1 16.1 0.0 5.8 2.9 5.8 11.4 5.1 0.0 15.3 4.5 13.8 6.8 1.0 2.0 14.4 3.2 4.5 3.1 0.9 1.9 45.6 3.9 12.5 1.3 3.3 6.5 5.4 0.0 19.5 8.4 3.2 5.9 14.8 3.6 5.8 0.2 0.0 0.2 0.3 1.8 5.5 0.1 0.6 0.6 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.4 0.5 0.2 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.5 0.6 0.2 0.2 0.0 0.8 0.1 0.2 0.3 0.1 0.0 31.9 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.5 0.0 22.5 0.3 1.4 0.1 0.0 0.3 0.1 0.2 0.4 0.4 0.1 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 9.9 0.6 47.2 16.1 0.0 5.1 0.0 2.0 1.3 0.0 5.8 80.2 6.4 11.2 0.3 46.7 23.1 31.9 43.8 39.3 2.3 73.0 68.2 47.1 0.0 12.2 0.0 0.0 1.3 9.3 3.5 0.0 3.3 18.4 47.1 52.7 36.5 284.3 0.0 16.0 4.2 1.3 33.9 35.2 116.6 108.7 21.8 37.5 0.5 4.7 0.0 0.9 19.2 8.2 19.0 20.3 11.6 3.1 27.8 21.4 3.7 0.0 5.1 0.0 1.0 0.7 4.5 2.2 0.4 3.7 16.1 0.2 0.1 5.7 1.3 0.0 41.3 35.9 0.3 0.2 16.5 50.0 9.7 11.5 6.5 7.0 9.8 PEBP4 "CORK1, hPEBP4, MGC22776" ENSG00000134020 "Phosphatidylethanolamine binding protein 4" Q96S96 8 22713251-23000000 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 382.5;skeletal muscle: 670.8;tongue: 581.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 109.0;Alveolar cells type 2: 177.3;Cardiomyocytes: 144.7;Muller glia cells: 198.7" "Group enriched" "Detected in many" 13 "lung cancer: 11.4;prostate cancer: 23.7;thyroid cancer: 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-266/70: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025064 Uncertain "Secreted in other tissues" NA NA 190000000 "Cluster 22: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "HPA025064: AB_1855174" "unprognostic (1.34e-2)" "unprognostic (2.97e-2)" "unprognostic (4.11e-2)" "unprognostic (3.66e-1)" "unprognostic (3.35e-1)" "unprognostic (4.78e-2)" "unprognostic (1.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.60e-1)" "unprognostic (1.74e-1)" "unprognostic (3.90e-2)" "unprognostic (8.76e-3)" "unprognostic (9.70e-8)" "unprognostic (1.13e-2)" "unprognostic (2.56e-1)" "unprognostic (3.48e-1)" "unprognostic (4.59e-1)" 1.1 3.4 12.3 0.3 16.7 0.0 3.3 21.2 9.2 0.6 19.2 0.6 0.0 0.5 382.5 6.8 2.2 1.1 200.7 8.5 15.8 2.6 0.9 115.1 0.7 15.6 20.3 1.7 34.5 82.6 13.2 0.3 20.2 45.8 0.2 12.9 21.1 2.8 670.8 1.4 0.6 0.4 8.7 0.8 9.2 6.6 28.7 1.2 56.7 581.4 1.6 0.3 0.5 15.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 12.3 16.7 21.2 9.2 8.5 15.8 15.6 20.3 20.2 8.7 28.7 15.5 1.5 109.0 177.3 15.3 2.2 1.9 1.0 0.1 0.0 10.2 5.7 4.7 144.7 0.0 7.4 1.8 2.1 0.8 1.4 0.3 3.9 0.0 34.8 1.7 2.0 2.4 0.0 0.0 10.0 9.3 0.2 10.1 2.0 7.0 7.6 0.4 3.9 0.7 1.2 10.1 9.6 0.3 2.0 0.0 0.8 28.4 3.4 1.4 1.8 6.5 0.1 198.7 5.2 6.6 0.9 0.3 0.1 10.9 1.5 23.8 0.5 5.9 2.9 8.6 0.0 25.2 2.1 14.8 1.2 0.0 0.9 0.0 1.6 1.1 0.3 1.0 RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 50.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 64.1;Alveolar cells type 2: 77.7;Excitatory neurons: 33.3;Proximal enterocytes: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 85.7;hTCEpi: 73.6;RT4: 126.9" "Low region specificity" "Detected in all" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA060938: AB_2684391" "unprognostic (2.67e-3)" "unprognostic (1.64e-1)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (7.83e-3)" "unprognostic (2.13e-2)" "unprognostic (8.13e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-3)" "unprognostic (1.93e-2)" "unprognostic (1.60e-2)" "unprognostic (1.46e-2)" "prognostic favorable (2.98e-4)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.43e-1)" 6.5 8.8 17.9 7.5 31.7 2.3 8.4 3.6 27.6 6.8 7.1 6.2 8.5 7.7 5.3 4.8 9.8 6.5 21.8 21.4 7.3 11.2 2.4 50.5 14.9 4.2 10.3 25.8 8.0 9.6 14.2 11.2 4.1 7.7 2.5 5.6 6.4 23.0 16.5 5.5 21.2 6.5 0.8 12.6 8.3 8.1 22.8 8.9 18.5 13.6 16.7 10.4 4.5 15.1 6.8 13.2 10.4 16.7 12.4 8.7 14.0 9.2 12.0 14.2 10.7 34.2 6.6 85.7 13.8 13.3 18.5 13.2 5.0 51.5 6.8 7.4 3.0 9.3 17.8 9.7 6.0 5.5 18.5 11.3 73.6 14.8 7.4 9.8 10.4 6.1 2.3 8.2 9.5 19.7 3.5 8.8 11.0 19.7 9.2 4.7 16.8 5.9 10.1 126.9 6.8 12.5 7.1 21.2 14.5 7.7 4.0 14.0 12.8 17.7 12.8 32.0 10.6 20.7 21.5 30.2 17.2 7.9 14.0 2.9 0.6 0.8 1.7 1.0 1.1 5.1 0.4 0.8 0.6 4.3 0.6 0.6 0.1 2.9 1.1 1.8 0.9 0.8 17.9 31.7 3.6 27.6 21.4 7.3 4.2 10.3 4.1 0.8 22.8 15.1 4.1 64.1 77.7 13.1 7.6 2.9 2.5 5.2 2.8 31.1 2.9 3.2 10.2 5.7 9.1 7.3 4.2 14.7 4.5 0.2 1.9 2.1 0.8 1.9 4.8 6.2 6.0 1.3 33.3 3.7 8.5 5.5 6.1 3.2 4.5 2.4 7.9 1.9 14.3 16.8 13.1 5.8 0.0 2.5 2.6 0.8 6.2 3.5 1.8 5.6 1.5 7.3 8.2 7.1 1.8 4.1 2.6 6.4 4.2 1.2 57.2 6.2 3.1 6.1 0.0 7.2 4.2 0.9 1.9 0.5 0.6 5.6 2.5 2.9 2.8 0.9 TNFRSF10B "CD262, DR5, KILLER, TRAIL-R2, TRAILR2, TRICK2A, TRICKB" ENSG00000120889 "TNF receptor superfamily member 10b" O14763 8 23020133-23069031 "Cancer-related genes, CD markers, Disease related genes, Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023625 Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA023625: AB_1847860" "unprognostic (8.43e-3)" "unprognostic (7.43e-3)" "unprognostic (3.04e-2)" "unprognostic (4.94e-3)" "unprognostic (1.13e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (9.51e-3)" "unprognostic (2.70e-1)" "unprognostic (2.82e-2)" "unprognostic (2.30e-3)" "unprognostic (1.96e-2)" "prognostic unfavorable (1.76e-4)" "unprognostic (4.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.86e-1)" "unprognostic (5.52e-2)" 20.7 21.8 4.4 17.1 4.0 13.9 16.8 3.7 4.2 10.7 19.5 14.7 22.0 11.1 6.8 10.4 13.5 23.9 14.0 4.8 3.9 15.1 34.7 22.9 14.9 4.7 4.8 17.8 21.9 19.6 6.5 13.6 4.4 12.2 21.7 1.1 13.2 10.7 10.6 6.9 25.0 16.2 4.8 17.4 14.1 5.1 5.9 8.3 16.8 4.8 16.7 31.1 9.5 4.7 39.0 98.4 144.6 46.5 71.7 93.7 143.0 91.2 123.5 50.7 77.6 40.9 39.1 23.1 59.1 52.4 88.4 37.2 39.3 179.7 90.4 22.9 31.2 0.0 43.6 85.4 238.0 9.6 37.5 136.1 164.6 110.5 121.1 131.9 160.4 27.5 16.1 0.2 104.5 12.3 0.8 14.3 37.0 52.6 34.6 21.0 53.5 14.8 100.2 62.7 0.2 24.2 46.4 14.0 51.1 101.6 23.1 9.9 145.3 71.8 36.4 23.2 66.6 27.4 4.7 10.8 74.6 17.8 106.6 3.8 17.8 0.6 1.9 12.6 3.0 4.0 2.4 2.0 15.8 1.9 4.7 1.9 3.6 1.2 17.5 0.0 1.6 7.8 4.4 4.0 3.7 4.2 4.8 3.9 4.7 4.8 4.4 4.8 5.9 4.7 41.8 12.8 35.6 8.1 17.6 31.6 35.0 55.9 34.7 0.8 31.7 26.7 3.7 12.8 36.4 12.9 0.0 4.2 10.4 28.4 3.9 29.1 1.3 42.2 16.8 39.4 0.0 4.0 3.3 26.5 8.8 18.8 60.6 81.9 9.5 17.1 18.9 27.1 9.8 0.0 1.1 20.8 14.2 21.3 69.6 2.3 7.2 33.1 19.6 38.4 15.5 2.6 1.0 15.1 0.6 50.7 22.6 6.8 5.1 37.7 36.4 9.2 18.7 0.3 0.0 15.4 14.3 0.3 2.1 25.3 18.2 4.2 14.3 21.0 26.0 53.1 AC107959.5 ENSG00000284956 "Novel protein" 8 23084403-23115536 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "gallbladder: 1.6;testis: 1.8" "Cell type enriched" "Detected in single" 13 "granulocytes: 1.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 7 "neutrophil: 221.6" "Lineage enriched" "Detected in many" 142 "granulocytes: 221.6" "Cell line enhanced" "Detected in many" "AN3-CA: 18.5;HDLM-2: 22.7" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: HDLM-2 - Immune response" "Cluster 60: Granulocytes - Receptor signaling" 0.2 1.0 0.6 0.5 0.6 1.2 0.0 0.4 0.7 0.1 1.0 0.1 0.2 0.0 0.1 0.1 0.0 1.6 0.0 0.5 0.6 1.0 0.0 0.1 0.0 0.6 0.5 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.5 0.3 0.1 1.8 0.5 0.0 0.2 0.2 0.1 0.0 0.5 3.4 5.6 1.0 18.5 0.0 3.6 3.7 0.0 0.7 0.4 3.4 0.7 1.3 3.7 5.0 1.6 1.2 0.1 0.8 0.8 2.7 22.7 1.9 0.0 2.4 11.5 2.0 0.6 7.5 2.0 2.6 1.1 0.9 4.5 3.6 0.5 0.9 0.0 0.8 0.3 0.0 1.1 4.2 4.4 0.8 0.1 1.1 0.4 1.0 0.2 0.3 0.1 0.4 2.3 5.7 1.3 2.2 0.4 1.4 5.9 7.8 8.2 0.9 7.7 6.6 0.4 7.5 1.7 5.6 2.4 1.5 31.4 0.0 0.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 221.6 0.2 1.4 0.0 0.0 0.4 0.6 0.6 0.4 0.7 0.5 0.6 0.6 0.5 0.6 0.5 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TNFRSF10C "CD263, DcR1, LIT, TRAILR3, TRID" ENSG00000173535 "TNF receptor superfamily member 10c" O14798 8 23102921-23117445 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 21.0;lymphoid tissue: 23.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 7.9;Endothelial cells: 5.3;Gastric mucus-secreting cells: 13.7;granulocytes: 8.8;Proximal enterocytes: 6.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 6 "neutrophil: 3195.8" "Lineage enriched" "Detected in many" 120 "granulocytes: 3195.8" "Group enriched" "Detected in many" 5 "BEWO: 108.8;HUVEC TERT2: 91.2" CAB025635 Enhanced NA NA 14600000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 60: Granulocytes - Receptor signaling" "CAB025635: " "unprognostic (2.63e-1)" "unprognostic (4.49e-3)" "unprognostic (7.21e-3)" "unprognostic (2.07e-2)" "unprognostic (3.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.81e-2)" "unprognostic (2.11e-3)" "unprognostic (5.56e-2)" "unprognostic (4.37e-2)" "unprognostic (8.98e-2)" "unprognostic (1.94e-3)" "unprognostic (2.74e-3)" "unprognostic (4.83e-1)" "unprognostic (1.84e-1)" "unprognostic (1.34e-3)" "unprognostic (6.54e-2)" 8.3 1.8 1.2 23.8 1.0 21.0 1.0 0.9 2.4 4.1 1.7 2.8 2.0 1.1 0.7 2.2 4.7 12.7 1.6 0.7 1.0 2.6 2.6 7.5 1.6 1.6 1.2 0.5 2.5 1.8 1.1 8.3 1.6 1.8 3.0 0.1 1.1 1.5 0.5 0.4 2.4 3.1 1.4 18.4 2.6 0.8 1.6 2.9 3.6 7.2 1.3 6.9 0.4 1.3 0.7 3.6 1.3 3.4 0.0 0.7 108.8 4.4 0.0 0.3 0.4 0.0 4.1 0.2 1.4 3.9 0.3 0.6 0.2 0.4 0.2 4.4 1.1 0.4 1.1 1.2 11.2 0.5 2.0 12.1 0.8 2.0 0.8 1.6 91.2 0.2 0.0 0.0 0.8 3.2 0.0 2.6 4.2 0.2 0.1 0.2 0.1 0.0 19.4 0.4 0.0 0.2 0.2 0.2 1.0 9.7 14.7 0.6 18.0 1.0 2.3 3.3 0.3 3.4 1.3 0.0 4.9 0.9 1.7 57.8 26.7 511.0 0.1 14.4 0.3 1.4 0.5 0.1 6.0 0.4 0.6 0.3 3195.8 1.4 21.5 0.4 0.4 9.2 1.2 1.0 0.9 2.4 0.7 1.0 1.6 1.2 1.6 1.4 1.6 1.3 1.0 6.4 7.9 0.3 0.2 0.3 0.3 1.5 0.6 0.0 0.1 0.0 0.4 2.8 4.7 3.7 0.0 1.1 0.0 0.3 0.0 0.4 1.0 0.5 0.1 5.3 1.8 0.0 0.1 0.4 0.9 0.8 13.7 0.2 8.8 0.0 1.8 0.0 2.4 0.0 0.0 0.5 0.0 1.6 0.6 0.4 0.0 2.5 0.0 1.0 1.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 6.2 0.0 1.8 0.1 0.0 0.4 0.3 0.6 1.5 0.2 0.1 1.1 0.9 0.3 0.4 0.4 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TNFRSF10A "Apo2, CD261, DR4, TRAILR-1, TRAILR1" ENSG00000104689 "TNF receptor superfamily member 10a" O00220 8 23190452-23225102 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050958, HPA054475" Approved Supported Nucleoplasm NA NA "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA050958: AB_2681290, HPA054475: AB_2682500" "unprognostic (3.66e-1)" "unprognostic (1.02e-1)" "unprognostic (2.19e-2)" "unprognostic (4.89e-2)" "unprognostic (9.44e-2)" "unprognostic (8.39e-2)" "unprognostic (5.32e-2)" "unprognostic (2.18e-2)" "unprognostic (2.72e-1)" "unprognostic (4.48e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (1.49e-1)" "unprognostic (1.99e-3)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (2.35e-1)" "unprognostic (2.87e-1)" 5.7 2.3 2.6 9.9 2.5 9.3 5.7 2.2 2.7 4.3 2.2 7.0 6.2 2.9 1.1 8.4 4.1 8.2 3.0 2.0 2.4 3.8 5.3 6.6 13.4 3.4 2.8 0.8 2.4 2.7 0.8 7.1 3.1 2.9 7.1 0.2 4.8 2.5 1.5 4.9 6.5 3.9 2.8 6.8 6.5 0.5 3.4 6.4 3.0 2.8 14.0 10.8 5.8 2.8 18.7 33.0 1.7 0.1 1.2 6.4 0.1 3.8 2.3 1.9 5.2 25.4 31.8 42.9 41.9 2.4 9.1 34.6 29.5 47.2 3.1 10.7 0.2 22.7 20.4 14.7 16.2 12.3 20.7 11.0 38.2 41.1 35.0 5.5 21.9 1.4 35.7 14.9 8.9 14.5 0.4 7.8 22.6 33.0 20.0 0.3 0.0 31.2 24.4 39.5 0.9 1.1 9.3 23.0 0.0 6.9 12.3 9.3 31.3 0.1 0.2 1.8 0.1 17.4 26.7 32.7 0.2 3.9 0.5 2.8 6.1 5.7 5.0 2.6 13.8 15.3 16.1 10.2 6.3 19.1 15.7 9.2 0.6 6.1 2.6 0.0 20.8 6.5 2.6 2.5 2.2 2.7 2.0 2.4 3.4 2.8 3.1 2.8 3.4 2.8 21.5 3.2 8.7 0.7 22.3 23.6 20.7 9.1 21.6 0.2 8.2 7.1 1.1 7.2 15.5 11.0 0.0 0.1 3.1 10.1 0.0 10.1 0.1 8.6 1.9 16.6 2.4 1.3 0.4 4.0 0.4 2.2 10.2 23.9 7.6 0.7 2.9 5.1 3.1 0.0 0.4 7.0 8.2 2.2 12.7 0.0 0.0 8.5 3.6 9.4 4.2 0.0 2.1 1.0 0.5 20.3 7.3 0.0 14.0 11.7 4.5 2.9 5.7 0.0 0.0 0.9 1.1 0.0 0.5 25.6 27.4 0.0 12.8 0.1 9.1 27.4 CHMP7 MGC29816 ENSG00000147457 "Charged multivesicular body protein 7" Q8WUX9 8 23243637-23262000 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 10 "B-cells: 35.7;T-cells: 76.3" "Cell line enhanced" "Detected in all" "Daudi: 39.7;U-698: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036119 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Cytosol "HPA036119: AB_10673000" "unprognostic (2.94e-3)" "unprognostic (1.64e-1)" "unprognostic (7.59e-3)" "unprognostic (4.51e-2)" "unprognostic (2.47e-1)" "unprognostic (2.83e-3)" "unprognostic (9.00e-2)" "unprognostic (1.84e-1)" "unprognostic (6.44e-2)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "unprognostic (8.98e-3)" "unprognostic (1.88e-2)" "unprognostic (6.80e-3)" "unprognostic (2.06e-1)" "unprognostic (7.54e-2)" "unprognostic (2.30e-1)" 4.6 5.9 2.3 19.5 2.4 9.8 4.5 3.6 3.2 5.1 1.4 6.0 4.0 6.2 1.4 4.8 4.9 3.4 3.9 2.3 2.9 3.4 3.5 4.7 32.8 3.4 2.0 4.4 2.7 2.7 3.6 2.1 3.5 4.1 3.4 2.2 5.2 3.6 7.0 4.6 14.7 2.6 1.9 16.9 5.8 4.8 2.9 31.0 4.4 3.9 27.7 5.6 4.7 4.8 6.2 8.6 4.6 7.8 4.2 4.0 5.2 5.0 3.6 7.2 6.1 9.6 4.8 39.7 6.0 3.7 6.9 5.9 4.3 6.3 2.9 10.6 7.4 8.4 11.5 4.9 3.6 2.4 11.4 3.4 4.2 7.0 1.9 4.1 6.0 16.7 9.3 5.6 4.2 6.0 7.3 9.3 7.1 5.9 6.5 2.8 3.7 5.5 3.7 8.0 5.6 5.5 3.9 5.9 2.3 2.5 6.2 4.5 6.7 8.9 5.7 6.7 4.0 15.1 8.5 47.2 6.6 6.6 6.6 1.2 4.8 5.0 6.3 4.8 12.7 35.7 41.3 19.0 3.7 35.6 76.3 45.2 4.3 5.4 3.5 3.0 46.8 32.7 2.3 2.4 3.6 3.2 2.3 2.9 3.4 2.0 3.5 1.9 2.9 4.8 8.6 6.4 7.9 7.2 48.6 13.6 15.8 12.1 12.5 11.9 11.3 10.9 13.2 11.5 11.8 14.7 4.2 15.8 12.7 16.9 19.6 19.7 43.5 5.5 11.3 12.1 13.8 8.6 9.3 15.8 18.8 11.1 11.7 10.2 12.0 13.1 6.4 7.0 15.9 13.5 11.4 13.1 14.2 7.5 7.7 13.7 9.9 13.1 16.0 1.9 17.3 20.6 21.6 3.5 9.5 20.5 12.4 10.5 24.0 15.9 16.0 18.8 7.1 10.6 6.6 10.1 13.1 15.7 16.8 9.2 10.7 20.7 25.7 10.1 10.8 19.6 R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 113.2;Rod photoreceptor cells: 115.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol "Intracellular and membrane" Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Nucleoplasm "HPA023073: AB_1855987, HPA023153: AB_2237834" "unprognostic (5.80e-2)" "unprognostic (4.70e-3)" "prognostic favorable (4.08e-4)" "unprognostic (7.46e-3)" "unprognostic (1.97e-1)" "unprognostic (7.26e-2)" "unprognostic (8.49e-3)" "unprognostic (1.02e-2)" "unprognostic (7.73e-2)" "unprognostic (2.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (7.65e-2)" "prognostic favorable (6.80e-5)" "unprognostic (1.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.18e-1)" "unprognostic (3.43e-1)" 20.5 21.9 41.2 15.2 52.7 29.0 19.6 53.7 43.8 23.4 36.4 33.6 19.7 23.9 14.8 16.1 22.5 16.2 33.1 39.9 42.3 20.1 28.2 16.7 22.5 60.9 49.8 27.2 42.8 29.0 22.6 13.7 63.6 22.7 15.3 62.7 35.7 19.9 54.5 22.5 20.4 22.2 49.3 20.2 28.4 30.8 48.6 20.3 17.6 31.5 18.8 22.2 17.8 73.7 38.2 48.7 36.7 35.9 15.2 20.6 25.2 24.7 23.4 41.0 29.7 35.0 17.6 38.1 25.6 30.2 28.0 28.3 38.9 45.8 27.5 24.7 41.6 35.7 33.4 29.2 36.0 24.7 25.6 24.8 35.5 35.0 16.4 30.1 31.7 42.9 41.8 31.0 24.3 33.1 55.6 43.8 29.8 40.4 35.8 37.9 44.8 22.8 20.3 41.9 47.2 41.1 28.1 32.8 41.8 25.0 30.3 29.2 27.4 37.9 31.8 32.2 51.1 23.8 22.2 39.3 29.5 34.3 48.5 38.4 50.5 82.5 64.8 44.1 56.5 56.5 52.7 55.0 56.7 42.1 40.5 47.0 31.3 59.5 50.3 52.9 61.5 51.4 41.2 52.7 53.7 43.8 39.9 42.3 60.9 49.8 63.6 49.3 48.6 73.7 25.2 25.6 14.7 4.9 15.5 14.9 16.5 35.9 10.2 28.0 22.8 32.9 24.1 24.3 20.5 5.5 27.1 18.8 19.8 17.9 56.7 32.3 36.4 15.2 17.0 21.1 19.2 17.9 5.1 50.9 21.3 25.4 20.9 10.2 22.8 24.7 20.0 21.6 30.2 18.5 5.0 21.5 22.4 18.2 12.3 113.2 17.7 16.2 21.4 5.6 18.8 59.3 42.2 4.5 9.5 37.0 22.1 21.8 34.7 11.4 41.7 38.5 22.0 115.7 13.1 19.9 31.1 49.8 32.4 13.6 16.2 7.7 18.3 30.7 22.8 13.6 LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 41.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 26.9;Endometrial stromal cells: 26.9;Endothelial cells: 33.1;Extravillous trophoblasts: 22.0;Fibroblasts: 22.9;Hepatic stellate cells: 19.6;Sertoli cells: 26.3;Smooth muscle cells: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 935.5;BJ hTERT+ SV40 Large T+ RasG12V: 517.3;fHDF/TERT166: 602.7;TIME: 510.7;U-87 MG: 905.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "CAB025848: , HPA036257: AB_2675025, HPA056542: AB_2683168" "unprognostic (9.48e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.03e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (5.55e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.46e-7)" "unprognostic (2.91e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (9.05e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.91e-7)" "unprognostic (1.51e-2)" "unprognostic (7.07e-2)" "unprognostic (4.93e-2)" "unprognostic (3.68e-3)" 30.4 3.3 1.9 15.9 2.7 1.2 18.8 4.7 3.0 10.6 0.8 25.3 9.3 12.0 0.9 3.8 4.9 8.0 10.7 1.8 3.2 6.1 3.9 8.3 11.7 7.7 8.1 12.9 6.5 2.5 2.6 36.2 7.0 7.5 5.4 3.0 4.1 13.0 4.5 5.4 10.3 41.3 4.5 5.0 9.0 2.3 4.5 1.8 5.2 2.6 9.5 12.0 7.3 3.7 58.2 147.7 42.7 35.8 112.4 183.8 19.4 935.5 295.9 415.6 517.3 1.1 4.4 10.7 7.5 602.7 193.2 47.6 2.1 79.0 215.3 1.8 8.5 0.9 19.4 1.0 226.8 0.5 3.8 164.6 3.9 155.0 20.8 274.0 350.7 2.4 0.5 2.0 138.1 32.3 0.6 1.4 29.1 0.4 24.5 1.9 36.7 0.4 120.1 0.3 0.9 13.7 122.9 6.1 8.6 131.3 0.8 1.2 510.7 384.6 103.3 163.8 127.3 4.1 0.8 29.9 905.4 1.4 413.5 0.1 0.2 0.8 0.4 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.2 0.6 0.3 0.1 0.2 0.2 0.1 0.2 1.9 2.7 4.7 3.0 1.8 3.2 7.7 8.1 7.0 4.5 4.5 3.7 12.9 0.0 3.0 6.8 0.6 2.5 0.3 26.9 0.6 1.5 0.6 9.7 2.6 1.5 4.1 0.0 0.0 2.7 0.4 0.0 0.0 1.9 0.6 1.7 26.9 33.1 0.0 0.0 8.1 1.5 22.0 22.9 1.5 2.1 0.0 2.0 19.6 0.2 1.3 1.7 3.2 0.1 0.0 0.3 5.7 0.4 0.9 0.9 3.6 6.5 0.0 1.2 0.0 7.1 11.9 2.3 0.1 0.4 0.9 0.6 0.2 0.2 1.6 3.2 26.3 2.7 48.1 1.3 1.6 0.5 3.1 1.0 1.0 3.1 0.4 0.2 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 8.6 24.2 10.5 30.5 14.8 11.1 16.2 17.0 8.1 19.8 18.1 16.8 17.3 12.6 13.7 14.6 21.2 10.8 12.3 12.2 13.7 20.0 29.3 13.1 9.2 13.5 21.4 27.2 18.3 17.2 12.8 16.8 20.3 32.7 22.0 13.4 15.2 12.4 26.2 16.5 7.6 25.4 20.3 19.9 12.5 14.5 14.7 15.9 29.8 16.7 16.6 11.6 20.8 28.7 34.0 23.5 29.0 36.8 35.0 33.1 30.4 21.3 33.2 40.3 26.4 35.5 22.9 32.8 32.9 24.5 15.8 29.0 40.3 8.6 11.5 18.4 18.1 14.2 23.7 9.8 34.8 22.8 34.7 28.4 29.9 51.9 31.2 26.7 13.2 30.6 36.4 9.3 14.8 11.9 20.1 26.2 10.2 14.3 34.6 10.8 27.0 24.1 27.2 26.6 12.0 17.0 23.7 67.0 12.9 13.6 38.6 39.1 38.3 43.7 24.1 24.7 11.5 45.5 51.3 11.5 39.4 17.0 5.7 13.4 7.4 8.6 8.8 8.7 7.3 8.1 7.5 6.5 9.2 7.3 14.4 4.8 7.0 6.8 6.3 6.9 8.6 10.5 11.1 16.2 10.8 12.3 13.1 9.2 12.8 7.6 12.5 11.6 15.9 19.2 34.5 10.7 25.8 6.5 12.0 17.6 8.6 32.1 11.4 8.6 24.6 7.2 27.3 14.7 14.6 16.1 33.4 25.1 0.0 15.6 8.6 13.6 21.6 15.8 17.3 10.3 31.4 16.9 16.9 16.9 23.9 23.9 17.7 18.9 12.1 11.5 12.3 47.1 37.4 19.7 20.3 14.2 15.5 19.2 7.2 18.2 12.4 19.7 19.4 15.2 18.6 23.1 23.1 21.8 13.3 8.6 46.9 18.9 18.8 5.0 15.0 35.9 13.1 14.3 14.6 21.5 22.8 9.5 5.5 20.2 21.3 11.7 12.4 18.9 SLC25A37 "HT015, MFRN, MFRN1, MSCP" ENSG00000147454 "Solute carrier family 25 member 37" Q9NYZ2 8 23528956-23575463 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Ion transport, Iron transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 138.4" "Cell type enhanced" "Detected in all" "Early spermatids: 707.8;Erythroid cells: 4197.2;Late spermatids: 1087.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 57.7" "Lineage enriched" "Detected in all" 19 "granulocytes: 57.7" "Cell line enhanced" "Detected in all" "HEL: 118.7;hTERT-RPE1: 65.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045680 Uncertain Approved Mitochondria,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria Cytosol "HPA045680: AB_10963693" "unprognostic (6.15e-3)" "unprognostic (7.33e-3)" "unprognostic (2.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.38e-1)" "unprognostic (5.12e-2)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (3.58e-2)" "unprognostic (1.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (4.37e-6)" "unprognostic (8.27e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 14.5 41.9 13.5 16.5 16.9 138.4 17.9 13.4 21.0 26.8 15.2 11.4 50.6 9.8 6.0 9.9 17.2 6.7 15.3 13.4 14.0 20.1 25.2 26.4 6.0 15.0 14.1 23.0 29.5 10.9 15.0 8.0 15.4 35.5 5.7 10.3 36.7 7.5 16.2 10.1 21.8 5.7 13.0 46.1 11.1 6.8 15.0 2.8 14.6 12.7 5.0 13.4 20.4 14.6 9.6 10.3 10.7 9.9 13.7 16.8 15.7 7.4 9.6 5.3 5.9 10.4 19.9 15.3 8.7 6.3 34.5 12.0 9.9 20.0 7.2 2.3 4.9 118.7 19.4 3.7 11.5 6.7 4.4 14.5 19.2 11.6 11.5 65.9 8.4 12.3 26.3 7.5 8.5 4.2 8.1 28.1 5.4 11.6 7.5 8.3 5.3 6.0 16.4 5.2 3.2 4.6 10.1 15.2 7.6 10.0 4.4 10.3 13.3 25.6 3.8 15.3 14.5 5.9 2.4 9.4 24.1 16.1 16.5 1.4 3.0 2.7 1.1 1.1 0.9 2.3 0.6 0.5 2.8 1.5 2.1 1.2 57.7 1.3 1.5 0.6 1.3 1.4 13.5 16.9 13.4 21.0 13.4 14.0 15.0 14.1 15.4 13.0 15.0 14.6 43.5 38.5 61.7 36.6 45.5 93.3 125.2 95.8 28.5 35.6 120.0 49.1 35.6 61.5 75.8 77.3 68.8 44.6 19.1 78.4 15.6 93.8 707.8 33.1 68.6 94.5 20.4 4197.2 44.0 226.4 76.4 95.4 43.8 50.0 36.8 49.7 151.3 38.8 41.7 6.7 37.3 44.7 36.7 59.0 141.2 1087.9 52.5 86.8 69.4 73.1 45.5 30.5 10.3 16.1 21.9 176.9 47.7 37.2 24.0 347.1 189.0 34.1 42.5 59.7 19.7 55.9 52.3 24.6 42.3 23.3 53.8 18.3 32.4 86.7 70.3 137.6 NKX3-1 "BAPX2, NKX3.1, NKX3A" ENSG00000167034 "NK3 homeobox 1" Q99801 8 23678697-23682938 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "prostate: 303.3" "Group enriched" "Detected in many" 6 "Basal prostatic cells: 51.0;Prostatic glandular cells: 124.8" "Cancer enriched" "Detected in many" 65 "prostate cancer: 392.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 54.0;neutrophil: 51.6" "Lineage enriched" "Detected in many" 21 "granulocytes: 54.0" "Cell line enhanced" "Detected in many" "GAMG: 25.7;SiHa: 26.1;U-138 MG: 25.8;U-251 MG: 23.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA025693, HPA078571" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 51: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Cytosol "HPA025693: AB_1854522, HPA078571: AB_2732384" "unprognostic (1.47e-2)" "unprognostic (4.03e-2)" "unprognostic (2.67e-1)" "unprognostic (5.87e-2)" "unprognostic (2.56e-6)" "unprognostic (6.90e-3)" "unprognostic (1.13e-1)" "unprognostic (4.11e-3)" "unprognostic (9.42e-2)" "unprognostic (1.41e-1)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (4.37e-2)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" 1.7 3.9 1.0 1.5 1.2 2.2 2.1 1.4 1.4 1.1 0.9 1.4 1.4 1.5 1.3 3.7 1.8 1.1 2.6 1.2 1.6 1.4 4.1 1.4 1.2 1.8 1.5 2.8 1.8 1.0 0.9 0.8 1.6 303.3 0.5 1.7 62.0 1.8 3.2 0.4 1.0 1.9 1.7 0.8 1.4 24.0 1.5 0.5 0.7 3.9 1.6 2.9 1.9 1.4 4.9 3.7 0.0 8.7 3.1 0.7 7.1 6.7 4.2 13.8 16.2 2.1 5.5 0.0 1.0 5.0 25.7 1.2 3.5 7.6 10.9 0.0 1.8 3.4 2.6 5.5 6.0 0.0 1.2 1.2 2.0 14.0 0.8 8.5 0.7 20.1 0.2 0.0 5.5 1.6 11.8 1.0 2.0 0.0 2.6 0.0 5.5 0.5 0.8 5.7 1.6 0.4 26.1 4.8 0.4 9.9 3.5 0.5 0.9 25.8 9.1 2.0 23.0 0.0 0.0 0.0 12.5 2.6 3.2 10.2 0.0 54.0 1.0 0.1 0.2 2.2 0.4 1.0 0.1 1.8 1.4 2.5 51.6 0.6 0.1 0.0 0.0 0.3 1.0 1.2 1.4 1.4 1.2 1.6 1.8 1.5 1.6 1.7 1.5 1.4 6.0 3.2 5.3 0.0 4.1 5.6 51.0 4.1 4.6 3.7 13.5 6.5 9.8 1.5 4.7 0.0 8.4 0.3 0.3 1.0 0.0 2.7 2.7 1.3 2.0 6.8 6.6 0.0 0.4 7.0 1.4 9.1 5.1 2.2 0.0 0.8 4.6 4.9 0.3 3.3 0.4 1.2 2.0 0.3 9.4 6.1 2.1 2.5 1.8 0.0 0.6 4.9 0.0 0.5 0.1 5.2 0.1 6.4 1.0 124.8 0.4 0.7 1.4 4.5 0.0 11.4 5.1 1.8 2.1 2.5 2.0 0.3 2.5 0.8 1.1 12.2 NKX2-6 "CSX2, NKX4-2" ENSG00000180053 "NK2 homeobox 6" A6NCS4 8 23701740-23706756 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "salivary gland: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTEC/SVTERT24-B: 5.6;JURKAT: 2.1;LHCN-M2: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025288 Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA025288: " "unprognostic (1.86e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STC1 STC ENSG00000159167 "Stanniocalcin 1" P52823 8 23841929-23854806 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 64.3" "Cell type enhanced" "Detected in many" "Adipocytes: 162.2;Collecting duct cells: 97.5;Endometrial ciliated cells: 84.0;Endothelial cells: 242.0;Glandular and luminal cells: 301.5;Theca cells: 214.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 348.4;hTEC/SVTERT24-B: 201.7;U-251 MG: 145.4;U-87 MG: 623.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB018625, HPA023918" Approved "Secreted in other tissues" NA NA 240000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "CAB018625: AB_2197536, HPA023918: AB_1857566" "unprognostic (1.18e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "prognostic unfavorable (6.44e-5)" "prognostic unfavorable (6.32e-4)" "unprognostic (2.84e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (4.82e-2)" "unprognostic (1.44e-2)" "unprognostic (7.61e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.23e-6)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.79e-1)" "unprognostic (1.19e-3)" "unprognostic (8.95e-3)" 44.7 3.1 2.1 2.6 1.4 0.1 26.2 2.0 5.8 49.4 13.8 7.4 1.7 32.4 0.6 7.0 5.9 14.8 25.7 4.1 3.9 17.9 4.0 10.5 0.7 4.5 4.3 2.8 13.7 10.5 28.9 29.1 4.5 9.3 1.9 8.3 10.3 7.3 2.6 3.0 2.9 7.5 3.4 0.2 10.4 0.2 4.7 1.5 64.3 6.4 1.3 44.4 10.2 2.9 1.5 1.3 1.9 0.0 13.0 14.3 0.3 20.6 348.4 6.7 31.5 0.1 0.0 0.1 30.0 6.8 116.6 1.1 0.8 5.1 58.0 2.2 0.4 0.1 0.0 0.0 0.9 0.0 0.5 65.1 0.0 201.7 0.5 96.4 2.8 0.0 0.6 0.5 28.8 0.0 0.0 0.1 8.4 0.0 1.0 0.0 0.3 0.0 11.7 0.0 0.8 0.0 31.4 2.1 2.1 2.3 21.3 0.4 27.0 82.3 3.1 1.6 145.4 0.0 0.1 0.1 623.7 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.4 2.0 5.8 4.1 3.9 4.5 4.3 4.5 3.4 4.7 2.9 162.2 3.2 13.6 0.0 0.2 22.7 2.4 15.7 0.0 3.1 75.3 8.0 3.3 32.9 3.7 97.5 0.0 0.9 0.0 0.8 0.0 37.0 0.1 84.0 42.7 242.0 0.0 0.0 0.2 0.2 6.1 67.9 2.6 301.5 1.3 0.2 23.2 0.0 2.5 8.4 0.3 0.0 0.0 0.3 25.8 0.2 5.0 1.5 17.8 0.0 0.0 0.9 0.0 0.0 0.1 6.7 0.0 0.0 1.2 7.6 0.0 0.1 0.5 2.1 0.0 0.5 7.4 0.0 0.0 0.3 20.6 1.9 2.6 214.5 1.0 9.6 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAMDEC1 M12.219 ENSG00000134028 "ADAM like decysin 1" O15204 8 24384285-24406013 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 424.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 14.8;Kupffer cells: 12.9;Macrophages: 25.5;monocytes: 5.2" "Cancer enhanced" "Detected in all" "testis cancer: 16.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 8 "U-266/70: 10.7;U-266/84: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA 28000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.17e-2)" "unprognostic (1.80e-2)" "unprognostic (4.15e-3)" "unprognostic (3.60e-1)" "unprognostic (6.21e-2)" "unprognostic (3.84e-3)" "unprognostic (2.12e-1)" "unprognostic (2.90e-1)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (1.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-2)" "unprognostic (3.66e-2)" "unprognostic (8.23e-2)" 0.6 0.5 0.0 52.1 0.0 0.3 0.6 0.0 0.8 0.4 0.0 215.4 189.4 0.9 0.2 0.9 0.1 3.2 0.4 0.1 0.0 0.2 0.1 1.6 73.3 0.3 0.0 0.1 0.2 0.0 0.0 7.8 0.3 0.8 311.5 0.0 0.7 0.4 0.0 0.4 424.9 11.6 0.0 5.8 5.9 0.3 0.4 5.7 0.3 0.0 27.2 20.6 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 10.7 2.7 0.0 0.0 0.0 0.0 0.0 0.7 1.9 0.0 0.8 0.0 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 2.2 0.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.1 0.0 0.0 12.9 2.0 0.0 0.0 25.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.1 ADAM7 "EAPI, GP-83" ENSG00000069206 "ADAM metallopeptidase domain 7" Q9H2U9 8 24440930-24526970 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 237 "epididymis: 3726.4" "Cell type enriched" "Detected in some" 7 "Early spermatids: 128.3" "Group enriched" "Detected in some" 16 "prostate cancer: 1.0;renal cancer: 0.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 30 "BEWO: 2.4;NB-4: 6.1;RPMI-8226: 1.7;SH-SY5Y: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA008879 Enhanced "Intracellular and membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 24: NB-4 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA008879: AB_10601789" "unprognostic (1.03e-3)" "unprognostic (3.96e-4)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 3726.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 15.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.8 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 128.3 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 16.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 689.9" "Cell type enhanced" "Detected in many" "Early spermatids: 92.6;Excitatory neurons: 46.6;Late spermatids: 114.6;Rod photoreceptor cells: 69.1;Spermatocytes: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 25 "HEK 293: 3890.8" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 220000 "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Intermediate filaments" "CAB010900: AB_477261, CAB012976: AB_2533154, HPA022845: AB_1854399, HPA023138: AB_1854398" "unprognostic (1.41e-2)" "unprognostic (1.83e-1)" "unprognostic (2.59e-2)" "unprognostic (9.38e-2)" "unprognostic (5.17e-2)" "unprognostic (6.32e-3)" "unprognostic (6.10e-3)" "unprognostic (2.57e-1)" "unprognostic (8.55e-3)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-2)" "unprognostic (1.38e-2)" "unprognostic (1.92e-1)" "unprognostic (4.76e-2)" "unprognostic (2.61e-2)" 0.3 19.5 61.1 0.9 27.9 0.0 0.1 150.0 689.9 9.6 0.0 2.8 0.1 4.0 0.0 4.0 5.3 0.2 0.2 57.7 54.0 1.9 0.1 0.2 0.1 610.3 89.1 1.7 2.0 0.0 17.9 0.2 487.1 1.5 0.7 90.8 0.3 27.6 1.7 0.6 1.3 2.5 86.8 0.1 0.9 18.9 430.5 1.7 0.1 0.7 0.5 0.4 6.5 203.6 0.0 0.0 154.3 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3890.8 0.0 0.0 0.0 79.4 0.0 0.1 2.4 0.1 0.6 0.0 0.0 0.0 0.7 0.0 0.2 5.9 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.7 0.1 3.7 32.6 0.0 0.0 0.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 27.9 150.0 689.9 57.7 54.0 610.3 89.1 487.1 86.8 430.5 203.6 3.1 0.0 0.0 12.4 0.0 1.3 0.2 0.1 9.1 30.9 1.1 21.2 2.4 0.0 0.6 0.0 6.2 0.0 3.2 0.1 0.0 0.1 92.6 0.7 19.5 2.9 3.5 0.0 46.6 0.2 0.0 2.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 20.2 17.5 0.0 0.0 0.0 0.7 114.6 0.9 0.7 1.8 13.1 0.0 22.8 0.0 9.5 13.6 0.0 0.0 4.5 0.4 0.3 0.0 0.4 0.0 69.1 0.0 3.3 5.7 43.8 1.0 14.0 0.3 0.0 4.1 0.0 0.1 0.4 NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 675.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 32.7;Distal tubular cells: 103.7;Enteroendocrine cells: 33.3;Excitatory neurons: 64.6;Horizontal cells: 30.3;Rod photoreceptor cells: 110.0" "Cancer enhanced" "Detected in many" "renal cancer: 24.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Group enriched" "Detected in some" 4 "HEK 293: 456.2;PC-3: 145.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 200000 "Cluster 32: T-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: AB_1854397, HPA015021: AB_2669135" "unprognostic (7.63e-2)" "unprognostic (1.36e-2)" "unprognostic (9.53e-2)" "unprognostic (6.81e-2)" "unprognostic (2.82e-2)" "unprognostic (6.69e-2)" "unprognostic (3.69e-2)" "unprognostic (3.78e-3)" "unprognostic (3.06e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.91e-4)" "unprognostic (5.76e-3)" "unprognostic (7.88e-2)" "unprognostic (3.97e-3)" "unprognostic (3.17e-3)" 0.1 18.0 35.4 1.3 36.7 0.0 0.0 103.6 675.9 2.0 0.0 2.5 0.6 0.1 0.3 5.4 1.3 0.1 0.1 50.9 75.6 5.0 0.0 0.0 0.1 425.7 41.1 0.2 0.2 0.1 4.0 0.0 231.3 1.8 1.5 89.5 0.0 15.6 0.0 0.9 1.9 1.1 33.9 0.2 0.8 1.7 216.1 12.7 0.7 0.1 0.3 0.0 1.4 184.0 0.0 0.6 68.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.7 0.0 0.6 0.0 0.0 456.2 0.0 0.0 0.0 21.6 0.0 1.0 8.3 2.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 18.8 0.0 145.4 0.0 0.0 0.0 31.7 4.2 30.9 31.6 11.2 0.0 1.9 2.2 0.0 0.0 0.0 2.2 31.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 1.2 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.2 1.5 35.4 36.7 103.6 675.9 50.9 75.6 425.7 41.1 231.3 33.9 216.1 184.0 0.1 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.6 32.7 0.0 0.0 3.2 0.0 0.0 0.0 8.4 0.0 0.1 0.1 103.7 0.1 0.4 0.1 0.3 3.7 33.3 0.0 64.6 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 30.3 29.1 0.1 0.0 0.0 0.0 0.7 0.0 0.2 0.0 27.2 0.1 27.8 0.0 14.6 18.4 0.0 0.1 9.4 0.0 0.0 0.0 0.2 0.0 110.0 0.0 0.1 0.2 0.0 13.2 1.5 0.0 0.0 1.6 1.4 0.0 0.0 DOCK5 FLJ21034 ENSG00000147459 "Dedicator of cytokinesis 5" Q9H7D0 8 25184689-25418082 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 86.0" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 789.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017719, HPA056837" Approved Enhanced Cytosol No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "HPA017719: AB_1847820, HPA056837: AB_2683253" "unprognostic (2.16e-1)" "unprognostic (3.55e-3)" "unprognostic (1.25e-2)" "prognostic favorable (1.91e-4)" "unprognostic (8.44e-2)" "unprognostic (1.24e-1)" "unprognostic (2.61e-2)" "unprognostic (2.88e-2)" "unprognostic (1.69e-2)" "unprognostic (4.21e-2)" "unprognostic (4.18e-3)" "unprognostic (3.00e-1)" "prognostic unfavorable (1.18e-6)" "unprognostic (2.81e-1)" "unprognostic (3.07e-1)" "unprognostic (1.30e-2)" "unprognostic (2.25e-1)" 4.9 3.4 17.1 7.5 56.6 17.0 4.8 33.4 30.0 4.4 25.2 8.4 10.6 4.1 5.1 3.4 6.2 5.8 7.8 19.5 29.1 4.3 15.2 9.3 1.8 43.4 39.9 6.8 4.7 2.6 8.2 10.2 43.6 7.9 9.4 2.5 6.7 5.6 2.6 5.4 12.9 3.3 19.3 19.3 6.6 6.2 40.7 1.9 15.5 2.8 1.6 4.1 4.9 86.0 19.8 43.2 4.1 0.3 9.8 10.6 14.2 45.5 26.5 12.4 9.6 6.3 15.5 0.4 4.0 40.3 13.7 34.6 4.9 32.5 19.9 6.2 6.1 20.2 40.5 15.8 11.1 5.0 21.6 7.3 12.9 13.6 20.3 13.6 10.7 0.8 0.3 0.8 12.2 11.5 0.7 9.5 4.1 24.4 11.9 0.3 9.0 0.5 9.1 12.0 3.0 1.4 24.0 14.5 4.7 3.4 4.5 4.0 32.1 21.1 13.6 25.5 17.1 0.7 0.2 0.3 27.4 10.2 27.4 14.6 2.5 3.8 0.4 5.5 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.3 30.7 0.4 6.8 0.4 0.0 0.3 17.1 56.6 33.4 30.0 19.5 29.1 43.4 39.9 43.6 19.3 40.7 86.0 2.7 44.8 41.5 96.6 2.2 18.5 13.2 30.5 2.2 9.6 12.8 5.8 13.4 31.5 31.4 14.7 2.1 28.3 20.1 50.6 0.0 10.3 0.9 16.3 10.0 10.6 17.5 9.9 4.9 12.0 100.2 28.1 32.1 53.1 31.0 52.8 8.2 35.0 13.3 1.7 3.6 26.7 8.2 60.3 51.0 5.6 28.9 41.3 85.4 38.4 24.5 20.0 22.6 61.3 789.8 48.9 27.4 48.2 13.4 36.0 60.0 6.2 20.9 2.3 13.1 4.0 12.1 0.9 5.6 5.8 7.2 20.5 10.8 25.1 27.7 16.8 GNRH1 "GNRH, GRH, LHRH" ENSG00000147437 "Gonadotropin releasing hormone 1" P01148 8 25419258-25424654 "Disease related genes, Human disease related genes, Predicted secreted proteins" Hormone "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 9.9;Peritubular cells: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 21.1" "Group enriched" "Detected in many" 4 "basal ganglia: 19.7;hypothalamus: 12.1;olfactory bulb: 6.7" "Group enriched" "Detected in some" 23 "basal ganglia: 14.1;hypothalamus: 32.3" HPA027532 Supported "Secreted to blood" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" "HPA027532: AB_10612111" "unprognostic (6.49e-3)" "unprognostic (7.62e-2)" "unprognostic (2.90e-1)" "unprognostic (5.06e-2)" "unprognostic (1.35e-1)" "unprognostic (3.53e-4)" "unprognostic (7.80e-3)" "unprognostic (2.97e-2)" "unprognostic (1.39e-1)" "unprognostic (7.99e-2)" "unprognostic (3.45e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (8.08e-9)" "unprognostic (7.98e-3)" "unprognostic (5.11e-2)" "unprognostic (3.49e-1)" "unprognostic (3.68e-2)" 5.1 2.3 5.4 1.4 8.8 3.0 4.9 7.7 7.2 9.0 6.4 6.7 1.9 4.2 4.7 5.7 6.2 1.8 7.7 5.4 15.8 6.0 3.2 6.8 2.2 6.5 6.2 8.6 4.0 0.6 4.7 1.4 6.8 8.3 1.7 9.2 5.4 1.7 3.1 8.6 5.9 1.0 5.2 7.0 4.3 4.6 6.7 1.9 4.4 1.0 1.7 5.7 8.5 8.1 1.0 1.5 4.0 2.2 1.4 4.7 1.7 3.7 1.4 1.1 1.7 1.5 1.1 1.3 0.8 2.1 2.6 3.8 1.2 0.3 2.7 1.7 3.3 1.4 5.9 1.5 1.1 0.2 1.4 2.6 2.1 0.8 0.7 3.6 0.9 1.3 1.5 1.1 1.8 0.6 1.4 3.2 1.4 1.2 0.5 0.9 0.6 0.6 1.0 0.7 21.1 0.7 1.1 0.7 1.4 1.5 0.7 1.8 3.4 3.1 1.5 3.8 1.5 0.3 0.2 1.8 1.5 1.0 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.0 5.4 8.8 7.7 7.2 5.4 15.8 6.5 6.2 6.8 5.2 6.7 8.1 2.4 0.0 0.5 3.3 1.1 5.0 1.9 1.7 5.2 3.6 2.5 1.3 1.8 1.5 1.4 3.7 4.2 0.1 1.0 2.3 0.0 0.2 0.3 0.7 0.6 2.1 1.8 0.0 3.0 0.6 0.4 3.1 0.0 1.0 0.0 1.0 1.4 0.3 0.5 0.0 2.8 0.5 0.0 0.8 2.2 0.5 9.9 0.4 3.6 2.8 0.8 0.6 4.1 1.5 1.7 0.6 0.6 9.8 1.8 3.7 1.8 0.2 0.9 3.9 0.0 2.4 1.9 1.8 1.2 3.4 2.4 0.1 1.4 0.5 1.4 1.8 KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042468, HPA047902" Supported "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: AB_2680205" "unprognostic (4.18e-2)" "unprognostic (3.90e-2)" "prognostic favorable (7.88e-4)" "unprognostic (7.04e-2)" "unprognostic (7.41e-2)" "unprognostic (1.05e-2)" "unprognostic (2.20e-2)" "unprognostic (6.01e-2)" "unprognostic (4.33e-1)" "unprognostic (2.43e-2)" "unprognostic (4.49e-3)" "unprognostic (2.30e-1)" "unprognostic (1.48e-1)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (4.97e-3)" 18.4 8.2 4.9 11.5 5.8 21.5 22.3 7.9 6.5 15.4 8.6 21.1 19.6 11.3 13.0 23.8 14.6 13.3 38.3 5.5 5.9 12.8 10.8 13.4 12.2 9.1 7.7 14.2 11.2 11.0 9.8 12.0 10.0 17.4 22.6 12.9 17.5 15.6 29.5 19.0 17.7 14.5 7.8 9.4 12.8 12.9 6.9 14.7 13.7 36.7 14.4 15.6 18.7 6.9 46.4 32.4 34.5 11.9 44.0 58.0 28.2 68.6 61.4 44.1 44.5 23.4 33.2 30.1 28.6 69.0 62.3 30.3 30.6 32.3 52.9 15.4 18.2 35.3 30.2 21.7 53.2 12.3 25.1 44.8 38.5 40.2 33.2 26.9 37.8 29.6 37.8 23.0 50.7 12.4 48.2 21.6 16.8 35.8 17.0 18.6 39.8 11.2 45.0 26.1 8.8 11.4 52.7 23.1 35.8 30.8 17.8 14.2 42.2 48.5 28.2 94.1 37.6 6.6 12.9 39.1 33.9 21.8 35.8 0.7 0.5 1.2 1.0 0.7 1.0 0.6 1.0 1.0 0.3 0.3 0.6 0.9 0.5 0.2 0.9 1.0 1.1 0.4 4.9 5.8 7.9 6.5 5.5 5.9 9.1 7.7 10.0 7.8 6.9 6.9 19.5 32.1 18.5 18.6 8.9 74.4 36.4 26.0 31.9 13.7 20.4 12.7 61.1 5.7 24.2 27.6 25.0 9.4 23.3 53.8 13.7 17.6 6.5 12.8 12.7 16.8 10.2 20.2 14.3 27.2 17.6 32.5 8.2 17.9 20.3 10.9 12.5 9.0 9.3 3.3 12.9 16.0 18.3 9.3 18.5 5.2 30.7 12.9 30.2 36.5 8.5 8.1 18.6 17.1 13.6 36.6 21.6 55.7 17.1 52.6 25.8 10.4 17.4 19.6 6.6 21.6 26.2 35.6 26.4 41.6 54.7 11.2 19.8 14.4 17.7 46.0 CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.5;lymphoid tissue: 11.4;testis: 19.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 23.3;Early spermatids: 49.9;Erythroid cells: 19.0;Late spermatids: 24.2;Spermatocytes: 66.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm Yes Yes "Cluster 15: NK-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA026293: AB_1846384, HPA030049: AB_10600862" "unprognostic (2.12e-1)" "unprognostic (4.75e-3)" "prognostic favorable (9.62e-4)" "unprognostic (2.92e-2)" "unprognostic (9.69e-2)" "unprognostic (3.56e-2)" "unprognostic (2.50e-5)" "unprognostic (1.47e-3)" "unprognostic (6.06e-2)" "unprognostic (2.91e-3)" "unprognostic (1.32e-3)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.30e-14)" "unprognostic (1.36e-2)" "unprognostic (4.02e-1)" "unprognostic (1.91e-1)" "unprognostic (5.30e-2)" 0.2 0.0 0.0 2.6 0.0 6.5 0.6 0.1 0.0 0.2 0.1 1.9 1.6 0.3 0.0 1.4 0.1 0.3 0.3 0.0 0.1 0.0 0.1 0.2 5.3 0.2 0.2 0.0 0.0 0.0 0.0 1.2 0.2 0.1 2.2 0.1 0.2 0.0 0.0 1.1 1.8 0.8 0.0 0.8 0.9 19.4 0.3 11.4 0.1 0.1 6.7 0.6 0.3 0.1 36.5 30.2 29.4 24.2 2.3 4.5 20.2 37.7 22.6 32.9 32.4 25.7 15.8 42.6 16.0 16.2 34.6 31.6 42.9 20.0 48.5 16.2 12.0 43.2 22.4 15.2 0.6 18.4 19.4 2.5 1.0 23.5 15.8 3.3 24.5 24.5 33.6 45.8 30.6 13.9 54.5 8.7 31.0 24.1 14.5 26.3 33.4 15.2 9.2 18.7 12.0 13.3 33.3 16.1 14.3 14.7 17.4 9.4 16.6 23.9 39.3 44.7 35.6 7.1 16.5 44.4 17.7 24.3 40.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.0 0.3 0.1 0.2 0.0 1.1 0.0 2.7 1.1 0.5 1.7 0.0 0.7 0.9 0.8 23.3 0.0 0.2 0.0 0.0 7.2 0.5 1.8 0.0 0.2 49.9 0.8 1.2 1.1 0.0 19.0 0.2 0.0 13.4 2.5 4.1 1.4 0.0 8.8 1.1 0.1 4.1 0.0 0.1 1.3 0.0 2.9 0.6 24.2 1.2 2.1 0.0 0.0 0.6 0.1 2.1 0.5 0.6 0.2 0.1 0.0 15.8 0.5 0.5 1.2 0.9 0.5 13.1 0.1 2.1 66.6 27.8 10.7 0.9 1.6 2.9 1.3 3.6 0.5 EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 17.8" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Fibroblasts: 23.2;Microglial cells: 13.1;Sertoli cells: 39.5;Smooth muscle cells: 53.4" "Cancer enhanced" "Detected in many" "renal cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 22.7;ASC TERT1: 45.7;HSkMC: 46.9;hTEC/SVTERT24-B: 26.7;U-138 MG: 17.1;U-2197: 22.7;U-87 MG: 19.1" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 8.7" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (3.70e-1)" "unprognostic (3.88e-3)" "unprognostic (2.69e-2)" "unprognostic (2.47e-3)" "unprognostic (1.03e-1)" "unprognostic (6.10e-2)" "unprognostic (5.92e-2)" "unprognostic (6.75e-2)" "unprognostic (1.11e-2)" "unprognostic (6.13e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (7.41e-4)" "unprognostic (2.28e-1)" "unprognostic (3.80e-2)" "unprognostic (1.82e-2)" 17.8 0.7 0.2 0.9 0.5 0.0 8.0 0.2 0.1 0.7 0.1 1.4 0.0 0.8 1.9 0.8 4.0 2.6 9.8 0.0 0.7 0.5 0.0 0.6 0.6 1.3 3.1 1.0 0.8 2.2 0.4 0.5 2.7 0.5 0.4 0.2 1.4 0.4 4.7 1.5 0.7 1.7 3.8 0.0 0.8 1.1 0.9 1.4 6.2 9.6 0.2 1.9 1.2 0.3 0.0 0.0 0.8 0.0 22.7 45.7 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 26.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 17.1 0.2 22.7 0.0 0.0 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.7 1.3 3.1 2.7 3.8 0.9 0.3 11.9 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.6 0.1 0.2 0.3 5.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 5.6 0.0 0.0 0.5 0.0 0.0 23.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.4 3.2 5.9 0.6 0.0 13.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 39.5 2.6 53.4 1.0 0.2 0.4 0.3 0.0 0.2 0.1 0.0 0.1 PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291508-26372680 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Cytosol "CAB079289: AB_659890, HPA042122: AB_2677859, HPA042770: AB_2678155" "unprognostic (1.17e-1)" "unprognostic (2.68e-2)" "unprognostic (4.29e-3)" "unprognostic (5.34e-2)" "unprognostic (3.44e-2)" "unprognostic (2.11e-2)" "unprognostic (4.64e-3)" "unprognostic (3.65e-1)" "unprognostic (2.48e-1)" "unprognostic (3.87e-2)" "unprognostic (2.71e-2)" "unprognostic (8.60e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-1)" "unprognostic (3.44e-2)" "unprognostic (1.16e-1)" 32.1 16.1 8.9 12.7 13.1 4.7 30.4 9.1 14.3 33.1 6.4 19.1 21.7 22.3 8.5 59.6 24.6 14.1 26.7 9.5 10.2 18.0 28.3 25.8 16.0 9.4 9.7 24.7 14.7 14.0 13.5 38.2 9.2 19.5 15.2 10.5 27.0 15.9 53.4 38.9 19.4 18.3 10.2 17.9 17.7 18.1 8.8 16.0 19.4 23.6 25.7 24.2 37.0 13.6 42.1 33.5 52.5 32.2 28.3 43.6 54.2 74.5 49.4 63.1 65.2 48.9 24.2 54.5 19.1 28.9 31.5 51.2 56.9 50.1 78.0 23.8 24.4 43.8 36.6 23.0 42.0 25.2 19.1 29.3 62.4 39.4 52.0 31.7 96.1 27.5 64.1 37.1 51.7 26.0 54.4 17.6 62.5 73.6 20.5 36.1 35.1 41.8 31.0 74.8 21.0 27.7 30.3 27.9 41.0 37.2 26.9 13.7 45.8 28.5 46.0 31.4 47.0 18.6 32.4 80.9 35.1 39.7 52.2 0.6 0.4 1.6 0.4 0.9 0.7 1.3 1.1 1.0 1.1 1.1 0.6 0.9 1.0 0.9 0.9 0.7 1.8 0.7 8.9 13.1 9.1 14.3 9.5 10.2 9.4 9.7 9.2 10.2 8.8 13.6 63.4 73.7 67.8 42.1 59.2 136.6 215.9 81.6 72.8 53.0 65.6 52.5 36.9 27.1 98.8 14.7 47.9 76.6 70.2 57.5 49.0 45.5 47.9 100.5 51.6 82.3 76.9 53.5 95.1 32.2 65.3 65.5 57.6 98.4 55.2 61.0 55.3 34.6 36.6 37.0 49.9 51.2 61.1 32.0 66.1 128.8 46.9 47.6 60.5 72.1 48.1 51.6 35.0 122.6 250.6 61.0 50.1 73.4 53.5 140.0 44.4 43.9 111.2 40.8 52.6 56.1 76.7 44.6 57.2 102.3 142.9 66.9 66.5 59.9 50.6 232.8 BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 913.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: AB_1845406" "unprognostic (1.02e-1)" "unprognostic (2.90e-1)" "unprognostic (2.00e-1)" "unprognostic (8.36e-2)" "unprognostic (6.24e-2)" "unprognostic (1.63e-1)" "unprognostic (1.64e-3)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (2.02e-1)" "unprognostic (2.06e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (5.92e-5)" "unprognostic (8.72e-3)" "unprognostic (5.16e-2)" "prognostic unfavorable (3.95e-4)" "unprognostic (7.59e-3)" 130.6 53.4 42.7 37.2 60.4 192.6 77.9 55.6 62.0 63.9 38.9 39.6 22.2 52.8 66.3 48.3 50.5 54.7 63.2 50.0 49.6 79.4 45.4 62.9 39.4 60.7 54.0 119.7 20.1 55.1 25.4 104.5 58.4 44.4 28.2 146.5 44.1 64.4 38.9 71.5 28.4 51.3 46.6 40.7 28.9 68.6 48.8 39.9 41.9 31.7 52.1 48.9 49.5 80.8 90.6 33.8 79.1 53.9 214.5 134.0 66.8 89.0 259.9 81.9 179.6 15.3 42.7 27.7 82.5 169.0 113.4 44.8 39.6 114.5 270.0 17.8 21.8 114.9 32.0 26.9 119.3 10.3 191.1 162.5 89.2 92.9 55.3 269.2 106.2 66.9 52.6 65.0 173.7 39.1 72.7 38.5 26.2 56.7 36.6 38.4 99.9 55.6 85.3 58.3 83.9 74.4 43.2 8.8 70.0 85.9 43.7 21.7 140.4 152.2 64.6 96.2 20.5 93.2 46.0 36.8 232.6 20.6 35.1 334.9 298.3 182.9 39.5 154.8 34.9 68.4 58.4 43.3 166.9 78.0 89.3 65.5 369.0 47.6 104.1 38.0 86.1 239.3 42.7 60.4 55.6 62.0 50.0 49.6 60.7 54.0 58.4 46.6 48.8 80.8 118.3 86.6 157.4 28.7 72.2 98.8 56.0 231.7 82.6 142.5 90.6 85.3 34.0 50.1 126.4 103.0 33.3 33.2 55.6 32.7 49.0 115.4 194.1 173.5 140.8 101.2 120.6 913.9 50.6 39.1 166.5 179.9 38.7 341.2 120.9 96.5 167.0 32.2 132.1 82.4 39.4 46.8 118.0 221.3 300.4 206.7 320.3 233.6 106.7 30.0 165.0 406.4 32.0 29.1 75.8 154.1 39.8 347.5 64.6 83.6 44.0 306.4 107.6 64.0 144.7 59.1 183.9 154.4 110.7 65.4 126.6 162.5 67.0 117.6 27.6 79.3 PNMA2 "MA2, RGAG2" ENSG00000240694 "PNMA family member 2" Q9UL42 8 26504701-26514092 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;retina: 24.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 71.2;Horizontal cells: 30.3;Inhibitory neurons: 92.0;Muller glia cells: 26.9" "Cancer enhanced" "Detected in many" "glioma: 28.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 63.0;hTERT-RPE1: 78.4;JURKAT: 43.3;SH-SY5Y: 44.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001936 Enhanced NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA001936: AB_1079647" "unprognostic (1.25e-2)" "unprognostic (1.27e-2)" "unprognostic (6.39e-2)" "unprognostic (1.43e-6)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" "unprognostic (8.76e-2)" "prognostic favorable (1.81e-4)" "unprognostic (4.66e-2)" "unprognostic (1.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.98e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.12e-2)" "unprognostic (4.58e-5)" "unprognostic (9.00e-3)" 2.6 10.8 52.2 1.2 55.1 0.4 1.9 1.3 73.4 3.5 0.0 1.4 0.8 0.8 1.0 0.5 2.5 3.9 4.9 55.1 88.4 3.2 0.9 6.8 0.4 29.0 25.7 0.8 3.9 2.7 15.4 0.5 28.7 0.8 0.9 24.5 0.3 0.9 0.5 0.6 1.1 1.9 16.5 0.5 2.8 1.7 67.0 0.2 2.7 0.2 0.3 2.2 0.8 29.2 0.0 11.7 63.0 0.6 12.2 2.6 0.1 3.2 17.2 7.8 2.6 0.5 8.4 0.0 2.3 1.2 19.3 0.2 39.5 0.0 6.0 0.0 7.0 0.0 8.7 0.1 0.9 0.0 0.4 4.2 0.0 33.4 0.2 78.4 37.7 43.3 0.0 0.1 4.9 0.3 19.3 0.1 34.7 0.7 0.1 0.1 12.8 0.0 18.7 4.3 30.7 44.9 0.0 0.1 2.1 4.5 0.2 1.2 18.6 0.8 12.7 16.1 2.6 5.9 4.6 0.1 36.1 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 52.2 55.1 1.3 73.4 55.1 88.4 29.0 25.7 28.7 16.5 67.0 29.2 0.4 3.2 13.0 20.5 0.6 0.0 0.1 0.2 0.0 6.5 0.9 1.1 0.5 0.0 3.7 0.0 2.1 0.0 0.0 0.1 0.0 0.3 5.4 1.0 4.5 1.0 10.8 0.0 71.2 0.0 0.1 3.6 0.0 1.5 1.3 0.0 0.4 0.1 0.1 30.3 92.0 0.5 0.0 1.6 0.8 1.5 11.1 0.1 1.8 12.2 0.0 26.9 0.0 19.1 11.5 2.7 0.0 12.0 0.0 0.0 0.0 5.4 2.9 6.2 0.0 0.2 4.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.2 0.2 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 STMN4 RB3 ENSG00000015592 "Stathmin 4" Q9H169 8 27235323-27258420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 333.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 45.6;Horizontal cells: 92.5;Oligodendrocyte precursor cells: 27.6;Oligodendrocytes: 217.4" "Cancer enriched" "Detected in some" 27 "glioma: 14.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 26 "SCLC-21H: 86.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027765 Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA027765: AB_1857607" "unprognostic (1.52e-1)" "unprognostic (3.45e-2)" "unprognostic (2.37e-2)" "unprognostic (3.19e-6)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (8.27e-2)" "unprognostic (1.37e-1)" "unprognostic (3.57e-3)" "unprognostic (2.36e-1)" "unprognostic (2.31e-3)" "unprognostic (9.84e-2)" "unprognostic (1.68e-3)" "unprognostic (1.37e-2)" "unprognostic (5.96e-2)" "unprognostic (4.15e-1)" "unprognostic (7.63e-2)" 0.3 10.2 128.0 0.2 147.2 0.1 0.2 154.9 333.3 0.5 66.3 4.3 0.6 0.4 0.9 0.1 0.3 0.2 0.1 148.1 150.9 0.1 0.1 0.1 0.0 185.1 152.3 0.2 0.1 0.0 1.1 0.0 184.4 0.5 1.4 21.4 0.1 0.2 0.2 0.4 1.6 0.6 151.1 0.0 0.9 0.6 150.9 0.0 0.1 0.0 0.0 0.6 0.6 265.7 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 86.8 3.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 128.0 147.2 154.9 333.3 148.1 150.9 185.1 152.3 184.4 151.1 150.9 265.7 0.1 0.0 0.0 4.6 0.0 0.4 0.1 0.0 0.0 45.6 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 92.5 18.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.6 0.0 9.7 0.0 27.6 217.4 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.8 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 TRIM35 "HLS5, KIAA1098, MAIR" ENSG00000104228 "Tripartite motif containing 35" Q9UPQ4 8 27284886-27311272 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 68.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019647 Approved Approved Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "HPA019647: AB_1858291" "unprognostic (7.67e-3)" "unprognostic (6.53e-2)" "unprognostic (1.61e-2)" "unprognostic (9.64e-3)" "unprognostic (9.35e-2)" "prognostic favorable (1.38e-4)" "unprognostic (8.79e-2)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (4.86e-2)" "prognostic favorable (5.59e-7)" "unprognostic (1.74e-2)" "unprognostic (1.69e-1)" "unprognostic (3.99e-2)" "unprognostic (1.92e-1)" 9.4 6.1 6.5 5.9 8.2 7.2 8.4 8.1 9.2 8.9 13.7 7.9 5.5 8.8 4.5 10.7 7.4 3.6 5.5 8.9 6.8 6.3 11.9 5.9 6.9 10.0 7.7 6.1 5.9 4.6 4.2 5.3 9.7 7.3 3.9 4.1 16.3 9.0 5.0 32.2 6.2 7.2 6.7 6.2 5.9 6.4 9.8 8.1 4.6 4.6 7.0 8.2 10.4 11.7 17.4 12.3 7.0 9.0 68.4 16.9 16.1 10.3 8.1 9.4 10.0 17.6 3.4 15.3 10.3 11.5 8.3 17.0 10.1 19.9 7.1 8.7 7.6 15.1 10.3 15.1 17.8 8.3 12.4 24.6 44.2 13.3 26.1 5.0 9.4 14.5 10.8 16.4 7.7 9.0 27.8 11.3 12.3 11.1 9.8 13.8 9.0 13.3 6.4 13.5 11.9 11.4 8.6 8.1 14.3 6.7 5.2 13.2 10.9 8.5 17.7 27.1 10.2 7.5 8.5 11.1 12.1 12.0 8.5 11.9 3.0 4.0 8.6 3.0 9.7 5.3 11.2 9.7 3.8 3.8 7.5 11.2 1.1 8.9 3.4 6.4 14.5 5.3 6.5 8.2 8.1 9.2 8.9 6.8 10.0 7.7 9.7 6.7 9.8 11.7 9.4 3.2 4.5 5.2 4.4 20.9 6.0 4.6 40.9 3.5 3.6 2.7 5.0 8.6 3.8 12.9 6.2 3.5 3.2 3.6 0.0 3.7 1.0 4.0 3.7 6.7 2.4 8.6 8.3 5.1 2.8 6.6 6.1 4.6 5.7 3.8 23.9 20.3 2.9 5.0 5.3 2.7 6.1 8.9 6.2 0.6 12.8 6.9 7.2 3.7 5.2 3.5 3.1 4.5 16.8 4.7 2.0 10.9 4.8 3.6 4.5 6.1 0.9 3.5 0.0 3.4 5.5 1.3 3.9 15.0 22.3 1.5 6.9 2.4 3.5 2.5 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;brain: 102.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 127.4;REH: 141.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favorable (5.11e-4)" "unprognostic (3.33e-3)" 19.7 10.8 46.9 52.6 54.4 106.3 11.5 22.8 102.9 11.5 38.3 29.8 34.1 9.9 8.9 19.2 15.6 12.7 10.6 96.3 8.5 15.9 15.2 28.6 78.3 0.0 26.0 4.7 12.6 7.1 13.7 8.0 0.0 25.5 23.5 4.4 26.6 12.3 5.0 45.2 48.8 10.7 0.2 78.3 22.2 9.5 27.0 86.0 12.5 5.4 73.6 21.0 15.1 37.0 38.2 10.4 2.8 3.0 76.6 5.5 21.5 2.9 1.9 1.9 2.7 9.9 21.5 127.4 4.0 5.8 3.1 34.3 1.1 31.3 1.1 8.7 0.8 26.4 10.6 2.0 15.7 28.5 45.5 41.6 46.0 2.6 17.3 13.0 1.0 36.0 31.7 85.6 2.1 4.0 49.1 57.0 2.2 33.0 2.6 141.2 0.7 88.3 8.5 29.5 19.2 3.5 13.4 9.3 5.0 6.5 11.5 72.1 17.5 1.3 2.8 2.5 1.0 68.0 32.0 68.9 5.2 60.6 2.4 47.3 48.4 36.9 33.9 43.0 22.2 46.0 17.0 24.3 36.1 46.6 20.8 25.9 45.8 29.0 53.5 11.7 18.2 50.1 46.9 54.4 22.8 102.9 96.3 8.5 0.0 26.0 0.0 0.2 27.0 37.0 6.9 3.2 29.8 16.6 64.3 37.7 38.7 19.7 6.8 5.4 5.9 7.7 3.7 8.6 13.0 14.7 0.0 2.9 33.4 65.5 0.0 8.0 1.2 7.1 1.8 9.6 7.8 20.2 109.2 8.3 26.5 3.5 22.4 5.3 28.5 1.1 5.0 24.1 23.1 8.4 9.2 21.9 10.2 68.4 32.1 1.0 1.5 55.3 8.8 22.5 62.5 2.8 70.0 7.5 15.1 13.3 42.0 0.7 68.1 18.6 44.6 16.1 13.9 3.9 0.0 3.3 3.3 4.2 6.4 4.8 30.1 1.9 46.6 1.0 18.1 17.9 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 EPHX2 ABHD20 ENSG00000120915 "Epoxide hydrolase 2" P34913 8 27490781-27545564 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aromatic hydrocarbons catabolism, Detoxification, Lipid metabolism" "Hydrolase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 333.2" "Cell type enhanced" "Detected in many" "Distal tubular cells: 180.0;Hepatocytes: 131.5;Proximal enterocytes: 399.0;Proximal tubular cells: 259.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory CD4 T-cell: 35.0;naive CD4 T-cell: 106.7;naive CD8 T-cell: 50.4;T-reg: 29.6" "Lineage enriched" "Detected in many" 23 "T-cells: 106.7" "Cell line enhanced" "Detected in many" "JURKAT: 139.4;K-562: 51.6;OE19: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023094, HPA023660" Enhanced Enhanced Cytosol NA NA 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "HPA023094: AB_1848214, HPA023660: AB_1848215" "unprognostic (1.30e-1)" "prognostic favorable (2.45e-4)" "unprognostic (2.99e-2)" "unprognostic (3.62e-2)" "unprognostic (1.76e-2)" "unprognostic (3.30e-3)" "unprognostic (1.26e-3)" "unprognostic (3.31e-3)" "unprognostic (1.46e-1)" "unprognostic (3.55e-2)" "unprognostic (4.14e-3)" "unprognostic (1.98e-1)" "prognostic favorable (1.98e-10)" "unprognostic (9.82e-2)" "unprognostic (1.73e-1)" "unprognostic (8.12e-2)" "unprognostic (2.26e-1)" 19.3 74.0 14.5 9.1 15.0 1.9 30.1 14.4 14.1 21.0 42.2 61.4 112.8 17.7 27.2 38.6 41.6 9.4 29.1 13.2 15.3 166.3 333.2 11.2 17.2 16.1 17.3 38.0 64.5 54.8 35.8 8.5 15.9 64.6 57.6 21.5 36.5 27.2 16.2 43.4 128.4 15.4 15.8 10.8 23.4 9.0 15.8 65.9 22.6 13.8 20.8 19.7 23.4 15.7 15.3 10.1 6.3 8.1 0.4 0.0 4.8 1.3 0.9 0.7 0.2 8.0 10.1 0.1 5.9 4.1 3.2 10.7 1.1 2.6 0.5 0.0 4.7 22.5 1.1 24.8 3.4 0.1 4.5 8.6 10.7 0.1 1.1 2.5 0.5 139.4 51.6 0.2 0.0 4.7 14.9 0.5 10.1 102.4 17.2 0.1 0.1 0.4 8.7 2.2 5.1 16.0 12.1 14.2 15.0 4.6 21.8 4.2 0.2 0.0 3.8 1.8 0.1 12.5 10.1 0.2 0.4 0.1 0.1 0.1 0.1 0.0 7.8 0.0 11.3 4.5 35.0 12.7 0.1 2.5 106.7 50.4 0.2 4.6 0.1 0.2 29.6 20.0 14.5 15.0 14.4 14.1 13.2 15.3 16.1 17.3 15.9 15.8 15.8 15.7 6.3 6.4 17.0 16.3 6.1 11.9 18.6 10.1 29.6 34.1 17.2 18.4 23.7 20.0 9.7 27.6 79.2 22.8 1.0 82.7 180.0 8.8 7.5 6.9 4.8 9.4 23.4 3.8 3.0 6.4 2.5 12.1 15.8 1.5 5.7 17.4 17.5 131.5 2.2 33.7 7.2 63.4 2.0 4.6 1.2 4.8 29.8 3.6 5.4 2.8 2.6 91.5 3.1 7.5 5.1 3.1 83.7 18.8 4.5 20.5 399.0 259.3 24.1 52.4 0.0 11.5 10.2 1.3 13.9 39.2 18.3 8.2 11.9 78.5 101.3 10.8 CLU "APOJ, CLI, CLU1, CLU2, KUB1, SGP-2, SP-40, TRPM-2" ENSG00000120885 Clusterin P10909 8 27596917-27614700 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Complement pathway, Immunity, Innate immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 10230.8;liver: 9779.1" "Group enriched" "Detected in all" 4 "Cholangiocytes: 2586.5;Collecting duct cells: 3525.7;Hepatocytes: 4230.2;Muller glia cells: 8522.6" "Cancer enhanced" "Detected in all" "glioma: 1485.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 767.1" "Lineage enriched" "Detected in all" 33 "granulocytes: 767.1" "Cell line enhanced" "Detected in all" "HeLa: 3644.3;SK-BR-3: 3500.4;T-47d: 2562.4;U-2 OS: 2225.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000572, CAB016253, HPA075983" Enhanced Supported Cytosol "Secreted to blood" NA NA 169000000000 29000000000 "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Cytosol "CAB016253: AB_673562, HPA000572: AB_1078539, HPA075983: " "unprognostic (1.10e-2)" "unprognostic (1.81e-2)" "unprognostic (1.14e-3)" "unprognostic (2.74e-2)" "unprognostic (5.59e-2)" "unprognostic (4.13e-2)" "unprognostic (1.76e-2)" "unprognostic (2.37e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-2)" "unprognostic (1.41e-1)" "unprognostic (1.80e-2)" "unprognostic (2.33e-2)" "unprognostic (1.72e-1)" "prognostic favorable (7.66e-5)" "unprognostic (5.29e-2)" 1438.7 3809.7 6730.2 897.0 6536.5 53.2 1423.8 6992.3 8050.5 1389.4 6057.7 1407.9 323.9 1152.5 9148.8 768.6 3543.7 2863.5 617.7 6660.5 8149.9 1170.5 9779.1 827.8 2309.4 10230.8 8450.9 756.7 2246.3 1689.2 827.2 131.2 8001.8 986.4 276.1 3274.6 1453.0 5466.4 114.1 281.9 662.7 1439.9 8813.6 295.4 1081.6 2709.4 7385.0 388.1 2406.8 267.7 2343.1 1777.4 741.0 9752.3 13.0 1673.1 73.2 86.4 401.4 546.1 230.7 297.8 584.8 77.3 40.1 323.4 265.5 6.6 1159.9 267.1 926.6 561.2 318.4 48.1 50.3 1268.7 306.4 741.8 3644.3 403.7 348.8 19.2 1891.2 923.4 189.1 334.0 95.5 719.5 1028.1 10.6 10.1 842.2 27.5 288.4 5.7 56.5 603.3 505.3 197.6 6.5 276.1 236.3 763.0 1220.2 66.7 41.7 412.3 3500.4 18.1 349.1 2562.4 10.3 153.2 24.0 2225.3 131.8 101.9 108.1 419.0 16.1 1808.8 122.4 10.3 767.1 18.4 8.9 19.8 6.2 7.4 0.7 23.1 21.3 6.2 1.6 2.8 7.0 79.8 9.3 1.1 11.8 6.5 1073.6 6730.2 6536.5 6992.3 8050.5 6660.5 8149.9 10230.8 8450.9 8001.8 8813.6 7385.0 9752.3 255.3 32.1 91.8 720.5 16.1 81.3 944.6 134.1 118.9 74.3 475.3 480.4 86.1 2586.5 514.0 3525.7 77.2 116.3 15.2 23.6 41.1 488.3 311.3 196.9 31.1 442.0 9.5 92.4 73.4 620.7 22.7 614.8 226.8 185.6 803.0 31.4 1037.7 4230.2 12.6 30.3 81.0 30.9 28.5 180.5 88.9 789.3 114.3 244.6 206.3 69.3 25.1 8522.6 11.3 61.3 54.3 174.8 15.0 57.2 11.6 200.5 9.9 459.2 709.1 221.4 13.1 334.4 157.7 189.8 20.3 58.8 55.3 85.6 58.7 288.9 49.3 353.7 SCARA3 "APC7, CSR, CSR1, MSLR1, MSRL1" ENSG00000168077 "Scavenger receptor class A member 3" Q6AZY7 8 27633868-27676776 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.5" "Cell type enhanced" "Detected in many" "Astrocytes: 238.6;Collecting duct cells: 66.2;Cytotrophoblasts: 45.8;Muller glia cells: 52.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 179.9;HeLa: 203.2;HUVEC TERT2: 140.1;U-2 OS: 120.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029861, HPA047386" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA029861: AB_2673225, HPA047386: AB_2680024" "unprognostic (2.24e-1)" "unprognostic (5.36e-3)" "unprognostic (2.68e-3)" "unprognostic (1.36e-1)" "unprognostic (1.48e-2)" "unprognostic (1.17e-1)" "unprognostic (4.31e-1)" "unprognostic (1.60e-1)" "unprognostic (3.58e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (1.78e-2)" "unprognostic (4.95e-2)" "unprognostic (6.31e-3)" "unprognostic (6.03e-3)" 23.8 7.2 53.4 15.7 58.6 0.0 17.6 55.6 57.8 58.7 29.9 34.5 5.0 87.9 9.5 23.7 86.8 30.5 13.9 50.3 68.1 11.3 3.9 15.2 13.4 136.5 89.5 13.8 4.1 1.5 9.6 19.5 79.2 25.6 8.5 8.8 35.7 66.5 2.6 17.5 15.4 68.1 80.3 2.8 14.7 3.2 79.2 15.9 51.3 8.0 23.0 31.1 20.7 71.4 1.8 61.0 9.4 0.2 49.9 179.9 40.0 23.8 38.2 25.8 19.1 22.7 15.8 0.0 52.7 50.3 21.1 44.5 0.1 44.9 12.7 0.2 5.1 17.8 203.2 0.8 5.3 0.0 0.1 75.6 2.9 40.2 2.3 35.0 140.1 4.6 0.0 0.2 15.0 11.8 0.2 0.1 12.3 0.0 22.3 0.1 0.0 0.3 8.2 27.4 0.2 5.9 5.7 32.0 0.1 4.8 31.1 0.5 49.9 20.7 120.1 77.2 12.8 0.1 0.1 0.2 35.7 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 58.6 55.6 57.8 50.3 68.1 136.5 89.5 79.2 80.3 79.2 71.4 2.3 0.0 0.5 238.6 0.0 3.6 16.2 4.8 14.8 1.0 12.6 19.8 2.2 8.6 6.0 66.2 0.0 45.8 0.6 0.1 0.0 0.4 2.9 3.8 10.1 6.4 0.0 0.0 38.4 0.8 20.4 25.1 1.5 2.0 0.0 5.3 15.4 0.4 4.7 0.0 30.4 0.1 0.0 0.3 2.1 1.3 15.8 0.5 17.8 21.5 0.6 52.4 0.0 19.1 18.1 2.2 0.1 6.4 0.0 5.4 0.0 0.0 6.5 1.5 6.6 1.8 14.7 0.2 1.5 6.2 3.8 8.2 0.3 1.9 0.3 10.3 CCDC25 FLJ10853 ENSG00000147419 "Coiled-coil domain containing 25" Q86WR0 8 27733316-27772653 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023256 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Golgi apparatus" Cytosol "HPA023256: AB_2072067" "unprognostic (1.43e-1)" "unprognostic (5.48e-2)" "unprognostic (3.10e-3)" "unprognostic (1.60e-1)" "unprognostic (4.39e-1)" "unprognostic (6.62e-3)" "unprognostic (2.34e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-1)" "unprognostic (8.49e-3)" "unprognostic (3.50e-1)" "unprognostic (2.69e-2)" "prognostic favorable (1.11e-7)" "unprognostic (3.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" 14.0 20.9 10.1 11.8 11.4 4.9 17.4 10.5 17.1 10.1 7.3 14.3 35.5 10.4 14.3 14.2 12.9 11.9 12.2 9.9 11.3 22.5 32.3 8.8 14.0 11.1 10.5 10.8 16.3 18.3 7.5 10.6 11.5 11.6 15.7 11.1 13.5 12.0 28.4 10.3 30.8 10.3 11.3 10.5 20.0 10.9 11.9 11.4 18.8 15.2 14.2 11.7 9.4 13.0 50.1 27.9 25.8 24.7 22.8 33.0 17.2 41.0 39.5 24.7 24.0 11.2 17.9 53.6 27.7 20.9 21.2 23.1 23.6 40.0 35.5 20.3 16.4 66.9 23.1 19.3 36.9 23.8 20.8 37.1 25.9 27.1 37.6 28.7 54.0 33.7 32.2 24.6 27.8 19.2 55.3 19.9 37.9 49.4 14.8 18.7 44.4 28.8 32.3 26.7 15.1 41.7 27.5 21.0 42.8 19.0 24.0 13.1 44.6 22.5 33.4 38.9 21.7 24.5 33.8 19.5 35.0 30.8 23.8 20.3 8.9 6.6 15.2 12.6 17.8 19.8 19.6 16.1 11.6 15.5 18.3 19.3 3.2 14.3 13.4 18.1 23.2 10.4 10.1 11.4 10.5 17.1 9.9 11.3 11.1 10.5 11.5 11.3 11.9 13.0 47.5 25.6 38.9 12.4 34.8 21.4 39.6 46.5 55.2 42.6 57.3 61.6 62.5 60.1 44.5 53.3 12.5 77.6 31.2 61.6 109.5 76.9 183.1 46.8 51.0 54.2 26.5 46.7 30.5 134.6 56.0 49.3 63.2 33.3 63.9 39.3 55.0 144.5 44.7 55.5 21.9 58.6 46.8 33.5 27.2 162.9 47.2 27.4 37.4 12.2 44.4 60.2 35.0 12.1 17.7 83.7 51.1 47.4 40.7 55.2 182.1 128.6 53.7 38.9 46.0 44.4 49.1 91.1 59.6 56.7 22.3 42.4 38.7 88.1 71.2 36.0 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 PBK "CT84, FLJ14385, Nori-3, SPK, TOPK" ENSG00000168078 "PDZ binding kinase" Q96KB5 8 27809624-27838082 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 22.8;testis: 70.3" "Group enriched" "Detected in many" 5 "Early spermatids: 364.9;Spermatocytes: 436.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 282.8" "Group enriched" "Detected in many" 4 "basal ganglia: 4.7;white matter: 13.9" "Not detected" "Not detected" "HPA005753, HPA050656" Enhanced Supported Approved Cytosol NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "HPA005753: AB_1855018, HPA050656: AB_2681205" "unprognostic (7.17e-2)" "unprognostic (7.21e-3)" "unprognostic (1.04e-3)" "unprognostic (2.77e-2)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (8.29e-5)" "unprognostic (3.65e-3)" "unprognostic (7.38e-2)" "unprognostic (2.88e-3)" "prognostic unfavorable (6.56e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (1.18e-12)" "unprognostic (9.61e-2)" "unprognostic (1.86e-1)" "unprognostic (8.30e-2)" "unprognostic (8.68e-2)" 1.1 0.6 0.1 6.6 0.1 9.1 2.3 0.0 0.1 1.1 0.0 8.9 8.4 1.2 0.0 6.6 0.6 0.7 0.2 0.1 0.1 0.4 1.1 0.7 12.8 0.1 0.3 0.2 0.4 0.2 0.0 5.1 0.2 0.4 10.1 0.0 0.9 0.0 0.2 4.8 8.1 2.7 0.1 1.5 3.6 70.3 0.3 22.8 0.5 0.1 12.4 1.6 2.1 0.1 282.8 94.2 94.4 57.9 8.3 15.7 36.9 129.5 63.0 133.2 112.3 33.7 51.2 156.4 43.3 51.7 150.2 76.4 87.6 44.7 145.7 35.8 48.0 35.0 64.6 49.2 0.6 25.7 54.1 4.4 36.0 62.6 32.8 24.3 68.5 75.9 54.3 100.6 160.4 34.5 87.7 29.1 15.6 80.1 80.0 54.4 126.9 41.2 51.2 44.9 36.1 53.2 48.2 56.0 75.0 26.2 58.0 37.3 40.6 85.6 207.3 111.5 141.5 15.4 39.4 70.1 54.0 43.4 188.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.3 0.2 0.1 0.3 0.1 0.2 0.0 0.0 0.0 4.2 8.9 2.8 10.8 0.0 0.0 2.9 2.4 0.5 2.8 2.6 0.0 0.0 29.8 1.3 5.5 0.0 0.6 364.9 2.5 2.2 2.4 0.0 61.7 0.1 0.0 49.3 6.7 6.6 3.5 0.0 13.5 5.7 1.7 5.0 0.0 0.1 9.4 6.1 1.9 1.6 76.8 8.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 3.0 14.0 2.0 1.5 0.3 0.1 0.0 6.6 0.1 5.8 436.4 38.1 9.4 2.4 6.7 1.9 2.4 18.7 3.8 SCARA5 "FLJ23907, MGC45780, NET33" ENSG00000168079 "Scavenger receptor class A member 5" Q6ZMJ2 8 27869883-27992673 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Iron transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 90.0" "Group enriched" "Detected in some" 4 "Fibroblasts: 174.0;Leydig cells: 135.8;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 121 "plasmacytoid DC: 21.1" "Lineage enriched" "Detected in single" 211 "dendritic cells: 21.1" "Cell line enriched" "Detected in some" 20 "ASC diff: 229.1" "Low region specificity" "Detected in single" "Region enriched" "Detected in many" 5 "spinal cord: 19.5" HPA024661 Approved NA NA 1400000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "HPA024661: AB_1853902" "unprognostic (2.76e-2)" "unprognostic (7.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.53e-2)" "unprognostic (2.34e-2)" "unprognostic (4.62e-2)" "unprognostic (2.01e-1)" "unprognostic (2.15e-1)" "unprognostic (9.13e-2)" "unprognostic (2.40e-1)" "unprognostic (4.21e-2)" "unprognostic (1.10e-1)" "unprognostic (7.09e-6)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" 60.5 4.0 0.4 7.2 0.8 0.0 34.6 0.8 1.8 16.6 4.9 38.5 8.7 2.9 8.2 21.1 23.7 22.5 90.0 0.6 0.4 1.0 4.1 20.2 2.4 0.3 0.2 11.2 2.4 0.2 5.4 12.5 0.2 8.4 33.7 0.3 29.0 3.3 15.1 31.1 26.3 6.5 0.5 3.3 27.3 11.6 0.2 3.2 21.1 34.5 2.1 77.1 36.8 0.3 0.0 7.9 0.0 0.0 229.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 0.0 0.0 11.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.0 0.1 0.4 0.8 0.8 1.8 0.6 0.4 0.3 0.2 0.2 0.5 0.2 0.3 7.1 0.0 0.0 0.0 0.1 6.5 0.1 0.0 0.6 0.0 0.5 0.6 4.6 0.0 0.0 0.0 0.0 0.1 6.7 0.2 0.0 0.0 1.5 0.7 27.9 2.4 0.0 0.0 0.3 0.0 0.4 174.0 4.1 0.8 0.0 0.0 0.0 0.0 0.4 0.0 2.9 0.0 0.0 0.0 17.0 4.6 135.8 1.3 7.2 5.6 0.0 1.9 0.0 0.0 0.2 0.0 0.0 11.3 0.8 0.1 0.0 0.0 0.0 0.1 0.0 7.4 3.6 0.7 1.1 0.9 6.0 0.1 1.1 44.5 0.3 0.1 NUGGC "C8orf80, HMFN0672, SLIP-GC" ENSG00000189233 "Nuclear GTPase, germinal center associated" Q68CJ6 8 28021964-28083936 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "liver: 20.6;lymphoid tissue: 22.9" "Cell type enhanced" "Detected in some" "Hepatocytes: 15.7;Plasma cells: 35.1;Proximal tubular cells: 7.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 3.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 4.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 116.5;Karpas-707: 38.6;U-698: 84.8" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "unprognostic (6.23e-2)" "unprognostic (2.17e-4)" "unprognostic (1.28e-2)" "unprognostic (1.96e-2)" "unprognostic (2.15e-2)" "unprognostic (1.83e-4)" "unprognostic (2.08e-3)" "unprognostic (6.19e-2)" "unprognostic (4.70e-2)" "unprognostic (1.59e-3)" "unprognostic (2.45e-1)" "unprognostic (1.95e-1)" "unprognostic (3.39e-3)" "unprognostic (1.84e-1)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (6.14e-2)" 0.4 0.3 1.2 6.2 0.6 0.9 0.8 1.2 1.8 0.1 2.7 1.9 1.9 0.2 0.2 0.4 0.3 0.4 0.2 1.1 1.1 5.1 20.6 0.8 18.7 1.8 1.2 0.5 0.2 0.0 0.0 0.1 1.7 0.3 1.5 0.3 1.3 0.2 0.3 0.5 2.3 0.1 0.1 2.7 2.6 0.4 0.7 0.5 2.1 0.0 22.9 1.6 0.1 3.7 0.1 0.2 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.0 0.0 1.0 0.3 116.5 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.2 0.3 1.1 0.0 0.2 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 38.6 0.0 0.1 2.4 0.2 0.1 0.3 0.0 1.1 0.2 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.3 0.6 0.0 0.1 0.3 0.1 0.1 15.2 1.4 84.8 0.2 0.2 0.0 1.0 0.4 0.2 4.0 0.3 0.5 1.6 1.8 2.6 0.1 0.6 0.3 1.0 0.8 0.5 0.1 0.3 0.1 0.5 1.2 0.6 1.2 1.8 1.1 1.1 1.8 1.2 1.7 0.1 0.7 3.7 0.2 0.0 2.2 0.0 5.0 0.3 0.3 0.0 0.0 0.1 0.1 0.0 0.7 0.0 3.7 1.8 0.0 0.0 2.2 0.0 1.9 0.0 1.1 0.1 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.5 3.1 0.1 1.3 0.0 0.0 15.7 0.0 0.0 0.5 0.0 0.0 0.6 1.1 1.5 0.0 0.4 0.0 0.0 0.1 0.1 2.1 0.5 0.2 0.0 0.0 0.0 35.1 0.2 0.0 7.8 0.0 0.3 0.0 0.4 0.3 0.1 0.0 0.0 1.0 0.0 4.6 0.1 0.0 0.3 ELP3 "FLJ10422, KAT9" ENSG00000134014 "Elongator acetyltransferase complex subunit 3" Q9H9T3 8 28089673-28191156 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation, tRNA processing" "Acyltransferase, RNA-binding, Transferase, tRNA-binding" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 74.3;Glandular and luminal cells: 125.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025297, HPA025812" Uncertain Enhanced Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Cytosol "HPA025297: , HPA025812: AB_10601369" "unprognostic (1.29e-2)" "unprognostic (1.26e-2)" "prognostic favorable (9.25e-4)" "unprognostic (3.49e-3)" "unprognostic (5.73e-2)" "unprognostic (1.10e-1)" "unprognostic (6.95e-2)" "unprognostic (2.07e-2)" "unprognostic (7.66e-2)" "unprognostic (1.22e-2)" "unprognostic (3.89e-1)" "unprognostic (3.46e-2)" "prognostic favorable (1.31e-5)" "unprognostic (2.29e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" 13.6 13.0 17.3 11.0 19.0 6.6 16.6 19.0 20.3 26.1 14.1 13.8 9.7 22.6 11.3 12.2 16.1 15.4 16.3 19.2 19.8 17.5 21.0 12.1 16.3 18.2 17.4 16.1 10.9 16.8 11.6 12.0 18.5 13.4 15.6 12.4 9.8 19.2 27.9 12.0 11.1 14.9 18.0 13.7 10.7 14.2 20.1 14.6 18.3 26.5 19.5 13.6 10.6 19.6 34.5 36.3 26.1 21.7 28.9 27.8 17.6 17.7 26.6 31.9 31.2 23.9 14.7 60.0 24.6 27.7 31.3 21.5 26.3 34.3 41.2 11.2 12.4 38.0 21.9 41.3 27.7 21.4 27.5 32.7 48.4 24.4 36.5 26.2 32.4 41.3 46.2 34.8 32.9 20.9 47.3 30.1 28.9 29.5 12.0 34.4 24.4 24.2 33.8 25.5 13.6 25.5 18.1 14.4 28.4 21.3 29.2 24.2 25.7 23.6 35.2 26.8 26.5 14.4 25.9 45.2 26.7 24.7 26.8 20.2 16.1 12.9 25.0 22.2 28.7 17.9 21.8 26.0 18.3 21.2 18.7 22.1 3.8 25.0 27.0 17.3 23.5 19.1 17.3 19.0 19.0 20.3 19.2 19.8 18.2 17.4 18.5 18.0 20.1 19.6 8.8 3.2 12.7 26.4 14.4 2.7 7.1 10.2 10.8 8.5 6.8 8.9 16.6 7.2 11.1 7.3 22.9 15.1 12.5 6.3 7.9 12.5 7.4 74.3 25.0 10.1 1.2 9.4 32.2 9.9 14.8 9.5 9.7 125.2 8.2 12.8 10.4 19.0 14.9 15.2 38.7 7.0 0.0 13.2 4.0 4.8 8.4 9.6 1.8 31.9 9.6 8.7 24.7 49.3 45.9 9.3 11.3 10.1 11.0 7.6 9.9 13.1 10.6 12.2 0.0 9.5 8.4 20.2 17.7 6.9 2.4 10.4 13.7 15.6 10.5 5.4 PNOC "N/OFQ, NOP, PPNOC" ENSG00000168081 Prepronociceptin Q13519 8 28316986-28343355 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Neuropeptide, Neurotransmitter, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.3;fallopian tube: 18.2;lymphoid tissue: 25.1" "Cell type enhanced" "Detected in some" "B-cells: 61.5;dendritic cells: 12.6;Inhibitory neurons: 23.3;Melanocytes: 14.2;Plasma cells: 80.4" "Cancer enriched" "Detected in many" 8 "ovarian cancer: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "memory B-cell: 231.2;naive B-cell: 260.3;plasmacytoid DC: 194.0" "Group enriched" "Detected in many" 20 "B-cells: 260.3;dendritic cells: 194.0" "Group enriched" "Detected in some" 6 "Daudi: 38.3;Karpas-707: 29.2;RPMI-8226: 11.2;U-698: 23.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044507, HPA056724" Enhanced "Secreted to blood" NA NA 12300 "Cluster 19: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA044507: AB_10795043, HPA056724: AB_2683216" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (3.53e-2)" "prognostic unfavorable (2.94e-6)" "unprognostic (3.71e-2)" "unprognostic (5.16e-5)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (7.81e-4)" "unprognostic (1.48e-1)" "unprognostic (1.66e-1)" "unprognostic (9.99e-3)" "unprognostic (7.57e-9)" "unprognostic (2.19e-2)" "unprognostic (5.45e-1)" "unprognostic (3.44e-1)" "unprognostic (1.40e-1)" 0.2 0.8 5.4 9.9 5.1 2.7 0.6 1.3 10.8 0.2 1.3 2.9 4.3 0.1 0.0 0.6 18.2 1.1 0.1 2.9 9.9 0.7 0.2 1.0 25.1 10.4 6.3 0.4 0.0 0.0 0.0 0.0 9.9 0.2 1.5 0.0 1.6 0.1 0.0 0.1 5.8 0.5 14.3 14.4 3.2 0.6 4.3 2.7 0.4 0.0 23.6 3.7 0.2 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 4.0 4.4 23.0 0.1 0.1 0.0 0.2 11.5 2.3 0.2 7.7 0.1 231.2 0.2 0.1 1.1 260.3 0.1 0.1 1.3 1.2 3.2 194.0 0.5 11.1 5.4 5.1 1.3 10.8 2.9 9.9 10.4 6.3 9.9 14.3 4.3 3.0 0.1 0.0 1.9 1.3 61.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 3.9 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.0 0.0 1.4 0.4 0.2 0.0 23.3 0.1 0.0 0.0 0.3 2.8 0.3 1.7 14.2 1.0 3.0 0.0 1.0 0.0 0.9 0.1 0.0 0.0 80.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.8 0.0 0.0 0.0 1.1 0.0 0.3 0.5 ZNF395 "DKFZp434K1210, HDBP2, PBF, PRF-1" ENSG00000186918 "Zinc finger protein 395" Q9H8N7 8 28345590-28402701 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "A-431: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049382, HPA076275" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 50: Non-specific - Ribosome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA049382: , HPA076275: " "unprognostic (1.28e-1)" "unprognostic (3.02e-1)" "unprognostic (1.95e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-2)" "unprognostic (4.51e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (9.35e-3)" "unprognostic (8.90e-2)" "unprognostic (2.15e-2)" "unprognostic (7.08e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (5.71e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (2.46e-2)" "unprognostic (7.42e-2)" 33.0 18.5 21.9 14.4 22.1 37.5 30.5 14.9 20.8 23.1 27.6 25.7 20.9 17.4 13.9 47.6 27.2 14.5 27.2 18.3 17.3 23.4 37.0 19.7 21.3 25.7 18.5 53.6 47.5 17.7 16.4 33.9 19.3 23.7 13.9 27.1 38.8 17.5 16.3 42.9 24.7 9.5 19.4 21.8 26.2 10.9 26.7 18.9 18.6 13.9 25.2 26.3 29.3 20.7 140.0 19.4 17.9 48.7 13.9 19.6 52.6 16.2 28.4 13.2 30.6 31.0 24.0 66.1 56.2 25.7 30.5 29.3 16.1 40.6 25.6 11.0 12.7 16.4 3.8 6.5 14.2 7.3 6.6 34.9 55.3 2.3 34.3 37.5 6.5 21.2 16.9 14.2 18.3 23.7 31.6 21.7 28.1 33.9 22.7 29.3 19.7 22.1 30.6 26.4 48.1 50.9 3.8 10.3 26.5 15.8 18.9 16.3 1.5 26.6 32.9 15.1 6.6 17.4 9.6 42.9 72.8 13.6 21.5 10.0 4.3 11.5 4.6 0.8 4.4 11.4 5.5 5.6 1.6 13.7 7.1 4.8 1.9 3.7 0.7 6.2 2.4 2.2 21.9 22.1 14.9 20.8 18.3 17.3 25.7 18.5 19.3 19.4 26.7 20.7 14.8 32.1 22.7 45.7 24.7 16.8 17.2 33.0 45.5 10.3 19.1 16.0 12.4 12.8 20.5 9.2 14.6 17.1 9.3 18.4 3.9 22.5 0.6 18.0 9.9 15.1 27.2 8.6 15.9 24.1 21.6 15.8 11.2 21.8 11.4 11.9 26.0 32.4 5.8 6.7 10.8 21.7 6.1 16.8 6.0 1.5 24.8 5.6 10.6 17.8 7.1 17.4 7.2 15.6 18.3 23.7 8.5 18.0 9.0 14.8 21.9 7.6 19.1 10.2 26.3 25.8 11.6 1.1 3.2 29.2 11.5 6.3 7.9 4.9 27.2 9.7 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 98.0;Excitatory neurons: 155.9;Inhibitory neurons: 82.3;Rod photoreceptor cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "AF22: 53.2;Karpas-707: 27.9;SCLC-21H: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" 1.0 2.9 5.2 1.5 6.7 1.5 2.3 5.7 9.9 2.4 13.8 2.2 1.3 3.4 6.9 1.9 3.5 1.3 1.1 6.8 4.0 2.6 0.6 1.0 2.1 1.8 5.4 7.0 3.5 4.2 3.8 1.3 4.2 4.3 1.2 14.7 3.3 5.5 1.2 1.5 1.0 2.4 0.9 0.6 2.5 5.0 3.2 1.8 3.4 1.3 1.4 1.9 1.6 2.6 14.8 3.1 53.2 10.2 0.0 0.8 7.9 0.5 1.1 3.0 1.3 3.1 3.1 6.9 2.6 0.3 6.6 5.2 8.0 8.8 2.1 9.1 5.8 4.8 1.0 2.0 0.0 2.7 7.9 0.6 4.1 0.2 2.3 0.6 0.6 7.3 3.5 27.9 0.1 3.7 0.2 5.8 13.3 6.4 4.6 3.3 8.0 6.8 4.0 4.4 39.6 10.7 2.9 7.5 8.7 7.0 7.4 4.0 0.0 0.0 14.3 2.0 3.7 5.1 6.1 6.7 4.2 0.0 2.7 0.7 0.2 0.0 1.6 0.2 2.1 1.1 1.2 2.3 0.9 0.6 1.6 1.6 0.1 0.9 0.0 9.3 0.0 0.7 5.2 6.7 5.7 9.9 6.8 4.0 1.8 5.4 4.2 0.9 3.2 2.6 1.7 9.6 12.0 65.6 5.6 6.6 7.9 17.0 10.8 28.1 21.6 11.7 6.0 4.3 17.7 9.2 98.0 10.5 15.7 1.4 1.9 12.1 25.7 24.2 18.7 4.3 28.7 5.0 155.9 14.9 9.7 8.8 8.2 27.7 5.7 29.3 8.6 3.0 4.2 21.9 82.3 6.3 8.2 1.0 7.4 11.9 48.1 2.1 33.8 14.0 0.7 17.0 2.1 52.8 14.3 11.8 3.4 51.1 17.2 14.1 0.8 11.4 17.5 87.1 26.3 8.6 15.0 58.4 45.6 5.6 4.7 4.8 5.0 15.0 5.4 7.7 EXTL3 "botv, REGR" ENSG00000012232 "Exostosin like glycosyltransferase 3" O43909 8 28600469-28755599 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025387 Approved NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 38: Heart - Muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "CAB025387: " "unprognostic (1.35e-1)" "unprognostic (1.31e-1)" "unprognostic (5.53e-2)" "unprognostic (1.19e-3)" "unprognostic (9.83e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (4.25e-2)" "unprognostic (9.29e-3)" "unprognostic (1.05e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-3)" "prognostic favorable (2.47e-5)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (8.91e-2)" "unprognostic (1.39e-2)" 10.8 16.5 11.3 7.2 12.0 3.8 6.3 7.6 13.7 8.9 5.8 11.1 5.5 13.8 5.4 12.3 11.3 7.9 31.1 14.7 10.4 7.0 6.2 8.6 5.4 10.7 14.3 10.0 11.9 18.9 10.3 13.8 7.2 8.5 5.4 11.2 8.1 11.8 20.8 11.1 6.7 17.9 8.9 8.6 9.0 10.3 23.4 6.4 7.7 22.7 4.8 10.6 7.2 12.7 45.3 33.6 70.1 37.0 18.8 18.5 15.6 33.7 32.6 20.3 16.4 28.9 15.9 12.2 46.6 40.1 28.2 29.7 34.5 55.1 22.4 8.9 18.9 17.2 15.7 14.3 9.8 8.6 46.9 22.2 36.7 15.9 14.6 16.9 44.3 17.4 16.2 15.4 16.5 8.5 15.5 4.7 49.2 13.3 13.6 18.4 31.3 7.1 31.2 29.0 15.2 26.6 14.3 8.6 17.3 22.0 8.4 9.4 34.9 26.6 62.7 25.4 28.9 7.9 17.9 13.5 22.5 10.3 23.7 3.0 1.3 2.0 1.7 0.9 0.8 0.3 0.7 0.9 1.3 0.4 0.5 0.4 5.7 0.5 1.4 1.1 0.3 0.8 11.3 12.0 7.6 13.7 14.7 10.4 10.7 14.3 7.2 8.9 23.4 12.7 6.3 3.2 4.4 10.4 2.4 5.0 2.9 8.7 6.8 17.5 4.8 4.2 26.8 7.2 5.0 1.8 25.0 3.7 7.1 4.9 3.9 9.7 32.0 4.2 7.0 7.3 4.2 1.3 20.0 10.6 16.9 6.5 4.1 5.9 5.7 3.0 8.2 9.0 4.4 8.4 19.0 2.4 2.0 6.6 2.5 10.1 9.9 6.1 5.4 16.9 5.7 6.7 23.7 13.0 16.6 12.3 2.4 14.3 4.2 6.3 2.1 3.5 4.9 16.2 26.3 8.4 9.6 4.3 9.1 4.3 3.0 2.2 4.5 8.6 3.1 3.1 INTS9 "CPSF2L, FLJ10871, RC-74" ENSG00000104299 "Integrator complex subunit 9" Q9NV88 8 28767661-28890242 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Excitatory neurons: 29.5;Inhibitory neurons: 31.3;Oligodendrocyte precursor cells: 32.2;Oligodendrocytes: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051615, HPA066822" Enhanced Nucleoplasm Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "HPA051615: AB_2681552, HPA066822: AB_2685729" "unprognostic (2.19e-2)" "unprognostic (1.45e-2)" "unprognostic (1.79e-2)" "prognostic favorable (9.45e-4)" "unprognostic (2.46e-1)" "unprognostic (1.56e-3)" "unprognostic (6.91e-3)" "prognostic favorable (7.71e-4)" "unprognostic (3.64e-2)" "unprognostic (5.01e-2)" "unprognostic (4.72e-2)" "unprognostic (2.48e-3)" "prognostic favorable (1.91e-5)" "unprognostic (2.51e-2)" "unprognostic (2.73e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" 8.6 22.0 7.9 11.1 8.9 6.8 8.3 8.7 9.4 9.1 10.5 8.8 6.9 9.2 11.3 11.1 9.7 6.7 12.2 7.9 8.6 10.7 5.9 8.8 14.6 8.5 8.8 8.2 9.7 9.5 12.5 7.9 8.6 9.1 9.3 10.5 8.9 7.2 11.6 9.9 9.6 9.0 8.6 15.7 9.4 12.8 8.9 17.5 10.6 6.9 17.9 11.0 8.7 9.4 24.7 17.0 20.1 21.4 24.3 11.3 8.8 11.1 15.1 19.0 20.9 11.9 13.4 24.4 15.2 11.4 17.0 20.1 39.2 22.7 26.1 10.3 16.1 24.4 9.5 21.0 17.6 12.3 18.2 13.0 16.0 22.9 16.3 10.2 23.8 34.5 52.2 13.7 12.8 13.5 57.5 22.3 27.4 28.8 10.9 36.5 23.3 12.8 13.4 16.8 14.4 26.4 11.5 14.8 20.5 16.0 14.4 13.8 14.1 10.9 27.6 18.7 14.2 7.0 5.3 29.8 16.8 20.3 15.8 17.0 20.6 19.0 17.3 23.0 16.1 18.0 15.1 19.3 29.1 19.5 13.4 14.5 8.3 25.1 17.4 15.4 20.3 12.0 7.9 8.9 8.7 9.4 7.9 8.6 8.5 8.8 8.6 8.6 8.9 9.4 3.6 6.4 4.2 28.7 10.9 2.3 2.4 4.7 1.8 2.1 2.7 2.3 5.8 5.7 3.7 3.7 6.2 7.7 6.1 2.8 1.9 3.7 8.3 4.8 6.2 4.6 6.0 4.2 29.5 5.1 4.8 4.7 9.2 5.9 0.0 6.7 3.9 2.5 7.5 1.7 31.3 3.6 4.1 3.8 6.1 4.1 7.8 4.1 3.6 23.4 5.4 2.4 4.1 32.2 39.9 4.9 1.7 4.5 4.3 1.9 3.3 4.3 3.4 6.1 0.0 4.2 4.0 5.1 3.5 7.7 3.0 4.8 5.4 11.2 3.5 1.7 HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.0" "Cell type enhanced" "Detected in all" "Astrocytes: 125.7;Oligodendrocyte precursor cells: 118.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: AB_11154826, HPA055855: AB_2682945, HPA058586: AB_2683764" "unprognostic (2.68e-3)" "unprognostic (2.30e-3)" "unprognostic (4.52e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.20e-1)" "unprognostic (2.75e-3)" "unprognostic (1.49e-1)" "unprognostic (4.25e-2)" "unprognostic (1.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.51e-1)" "unprognostic (3.84e-2)" "unprognostic (2.81e-1)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" 4.6 6.7 7.6 5.1 11.9 10.8 4.2 10.6 5.7 3.7 1.7 3.8 3.1 4.4 3.0 3.2 3.7 4.2 4.5 5.3 17.9 4.3 4.2 4.6 5.3 15.0 20.0 6.1 3.3 5.0 1.8 6.8 15.6 2.9 3.9 6.2 3.1 2.5 2.8 4.4 4.3 5.2 10.4 5.7 4.3 7.6 11.6 4.9 6.2 3.7 5.9 3.8 2.4 12.9 6.2 6.8 7.1 8.2 6.5 6.7 6.0 2.6 3.5 4.0 4.3 3.1 3.9 15.1 6.3 4.5 6.0 5.3 14.4 5.3 5.6 5.5 2.4 15.6 13.8 4.2 5.3 5.4 10.2 3.3 7.5 5.3 10.1 4.9 9.1 9.0 22.7 14.4 5.7 3.8 9.9 2.7 5.0 6.6 1.6 8.1 7.1 3.4 2.8 11.5 3.0 9.2 5.1 3.9 5.4 5.9 3.9 4.8 13.0 3.6 16.8 3.9 3.8 4.4 4.8 5.9 4.6 6.5 5.4 3.2 2.4 1.1 1.9 2.6 2.7 3.4 1.9 1.8 2.5 2.6 2.4 2.4 1.4 1.2 4.7 1.9 0.8 1.4 7.6 11.9 10.6 5.7 5.3 17.9 15.0 20.0 15.6 10.4 11.6 12.9 25.5 16.0 18.1 125.7 30.3 16.7 15.8 18.1 15.9 24.4 15.3 10.5 23.6 20.0 14.0 29.5 39.6 12.9 18.7 16.2 15.6 8.3 93.0 15.0 21.2 34.2 17.4 19.6 90.1 14.4 14.1 19.2 11.2 29.4 17.1 36.7 68.6 13.7 10.3 30.3 109.8 12.9 22.4 19.8 36.4 31.5 35.8 20.1 16.0 91.8 21.4 28.3 26.8 118.1 111.8 14.1 11.3 31.6 14.4 21.0 20.4 8.8 14.3 31.6 19.7 34.6 17.3 43.6 15.2 10.1 19.7 19.2 22.8 19.5 14.7 22.6 KIF13B "GAKIN, KIAA0639" ENSG00000197892 "Kinesin family member 13B" Q9NQT8 8 29067278-29263124 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "brain: 64.5;parathyroid gland: 161.5" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 140.2;Oligodendrocytes: 371.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025023, HPA049655" Enhanced NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "HPA025023: AB_1852471, HPA049655: AB_2732555" "unprognostic (1.37e-1)" "unprognostic (4.31e-1)" "prognostic favorable (8.92e-4)" "unprognostic (1.35e-3)" "unprognostic (2.27e-1)" "prognostic favorable (6.26e-4)" "unprognostic (1.04e-1)" "unprognostic (1.66e-1)" "unprognostic (1.21e-2)" "unprognostic (9.69e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (9.76e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.19e-1)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" 7.4 11.7 25.9 6.8 47.6 5.1 9.2 34.9 30.6 8.7 16.6 18.3 16.1 6.7 9.4 8.4 7.1 8.4 5.3 20.0 29.4 18.5 10.2 8.5 4.3 47.3 43.7 7.2 10.9 161.5 10.0 3.8 42.1 10.9 13.8 7.9 15.6 8.5 4.7 20.0 15.7 5.5 29.3 8.9 19.2 6.6 40.1 5.1 9.0 3.0 4.6 9.5 6.1 64.5 12.4 13.2 4.6 3.8 7.5 4.3 6.7 0.7 2.9 3.9 6.2 8.3 6.9 2.6 6.9 0.8 7.1 8.2 3.7 2.1 5.1 3.9 3.6 6.6 1.8 8.4 7.2 1.8 19.2 5.0 3.9 8.9 3.6 8.3 17.1 4.9 8.6 9.5 12.9 3.8 9.7 3.1 2.3 17.4 2.2 5.5 10.6 4.9 17.0 13.2 1.3 9.1 2.4 8.0 11.7 4.8 5.9 3.7 22.8 2.8 7.6 0.8 5.6 6.9 11.1 4.4 16.4 3.4 13.2 0.1 1.5 1.7 1.5 1.1 0.7 1.4 0.6 0.9 0.5 0.8 0.5 0.6 0.7 0.9 0.6 2.2 0.6 0.5 25.9 47.6 34.9 30.6 20.0 29.4 47.3 43.7 42.1 29.3 40.1 64.5 22.2 44.8 24.8 30.0 16.5 4.5 13.8 17.2 5.2 13.3 23.5 11.2 5.3 20.0 36.8 35.0 60.5 6.4 35.8 95.8 11.7 25.7 8.0 55.3 12.7 14.2 25.2 7.4 26.7 25.0 0.9 10.0 55.0 140.2 41.0 10.6 13.9 18.6 8.9 16.8 35.3 44.1 36.7 25.7 6.3 3.5 8.1 24.4 7.2 41.2 12.1 9.5 12.3 47.3 371.1 39.7 58.0 20.3 42.5 28.1 34.7 17.8 34.9 26.2 6.6 36.4 7.4 6.3 7.7 9.8 6.8 5.1 31.8 5.9 36.0 32.5 DUSP4 "HVH2, MKP-2, TYP" ENSG00000120875 "Dual specificity phosphatase 4" Q13115 8 29333064-29350684 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 32.2;stomach 1: 32.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 155.5;Ionocytes: 126.1;Pancreatic endocrine cells: 195.2" "Cancer enhanced" "Detected in all" "melanoma: 42.9" "Region enhanced" "Detected in many" "hippocampal formation: 20.9" "Immune cell enriched" "Detected in single" 9 "T-reg: 6.7" "Lineage enriched" "Detected in single" 20 "T-cells: 6.7" "Cell line enhanced" "Detected in many" "A549: 100.0;OE19: 91.7;SK-MEL-30: 157.2;WM-115: 122.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061967 Supported Nucleoplasm NA NA "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA061967: AB_2684648" "unprognostic (1.92e-1)" "unprognostic (5.97e-3)" "unprognostic (3.24e-1)" "unprognostic (6.54e-2)" "unprognostic (2.18e-2)" "unprognostic (7.66e-3)" "unprognostic (7.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.83e-2)" "unprognostic (9.73e-3)" "unprognostic (9.60e-3)" "unprognostic (3.15e-2)" "prognostic unfavorable (4.19e-4)" "unprognostic (6.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-2)" "unprognostic (6.07e-2)" 15.2 5.2 2.3 5.4 1.4 6.2 23.7 5.0 9.0 6.0 0.4 1.2 1.2 4.5 0.1 2.5 1.9 11.3 2.3 20.9 1.2 2.8 0.7 5.7 2.6 1.6 1.1 0.4 32.2 0.6 5.3 7.5 1.1 5.2 1.4 5.9 16.1 10.1 4.2 5.6 2.0 1.2 0.3 1.0 32.4 2.8 2.9 4.2 1.2 0.9 2.7 13.8 2.8 1.1 38.0 100.0 57.9 2.8 7.2 0.0 4.9 7.7 42.0 22.8 10.1 1.1 18.8 0.0 20.5 3.6 16.0 12.0 0.7 25.7 13.5 1.0 1.9 0.3 3.7 0.7 0.2 0.5 47.3 4.6 16.7 7.1 42.1 49.7 18.9 0.4 0.3 4.5 46.0 42.9 0.1 7.1 10.1 91.7 60.5 1.2 1.9 8.1 52.3 19.7 0.4 32.0 10.8 49.5 157.2 1.1 10.7 1.1 53.3 16.7 0.3 0.0 5.7 11.6 1.4 0.1 50.2 8.9 122.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 6.7 0.0 2.3 1.4 5.0 9.0 20.9 1.2 1.6 1.1 1.1 0.3 2.9 1.1 11.1 0.0 2.8 0.0 33.5 12.1 98.3 27.3 4.0 43.2 80.4 62.2 2.6 51.5 51.1 0.0 12.5 3.2 24.0 1.9 0.0 74.3 7.6 64.7 13.3 16.3 97.8 0.0 3.8 78.6 40.9 9.6 121.8 155.5 6.3 0.0 21.8 0.3 25.0 43.7 8.2 8.5 126.1 4.0 102.8 25.6 0.3 47.4 65.8 0.0 75.6 0.8 0.0 1.5 0.3 195.2 0.0 0.0 31.0 30.9 0.4 0.2 43.6 3.4 13.1 18.9 17.8 1.4 8.2 2.3 11.9 17.8 115.6 0.1 4.6 102.7 SARAF "MGC8721, TMEM66" ENSG00000133872 "Store-operated calcium entry associated regulatory factor" Q96BY9 8 30063003-30083208 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040400 Supported "Endoplasmic reticulum,Rods & Rings" NA NA 41000 "Cluster 20: T-cells - T-cell receptor" "Cluster 68: Epididymis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum" "Rods & Rings" "HPA040400: AB_2676962" "unprognostic (1.11e-1)" "unprognostic (4.78e-2)" "unprognostic (4.27e-3)" "unprognostic (1.38e-3)" "unprognostic (7.86e-3)" "unprognostic (1.91e-1)" "unprognostic (2.32e-1)" "prognostic favorable (5.28e-4)" "unprognostic (1.98e-1)" "unprognostic (1.74e-2)" "unprognostic (8.03e-2)" "unprognostic (6.70e-3)" "unprognostic (1.06e-2)" "unprognostic (5.09e-2)" "unprognostic (3.88e-2)" "unprognostic (3.87e-2)" "unprognostic (2.18e-1)" 139.9 294.5 208.6 169.1 228.0 253.0 169.9 187.2 246.6 153.8 196.2 143.0 123.9 152.1 408.6 91.0 205.9 182.1 151.8 234.6 308.8 205.2 302.3 167.5 218.9 214.0 258.8 255.7 231.4 236.5 138.9 309.2 247.6 228.2 143.5 219.1 212.9 172.7 111.1 70.8 140.5 139.1 219.5 159.0 161.1 104.3 290.5 243.4 245.4 129.0 186.5 141.0 64.0 218.5 119.9 112.4 147.9 79.9 209.3 149.8 69.7 139.2 247.0 128.5 173.7 72.2 139.9 80.9 183.5 156.0 134.7 97.7 100.8 112.4 146.9 33.6 49.5 112.2 87.3 119.2 189.6 48.8 130.6 175.2 260.0 121.6 125.5 257.4 192.0 150.7 128.4 191.2 142.9 74.2 128.4 88.8 96.0 253.6 61.3 98.7 88.4 107.4 220.3 100.4 48.6 162.5 140.6 160.5 208.2 115.7 112.2 93.3 144.0 89.6 230.5 35.0 56.5 103.4 110.6 81.0 215.8 118.4 146.5 964.6 252.9 443.1 321.2 253.2 364.8 233.1 473.0 377.9 247.0 302.4 776.2 543.6 478.1 258.8 335.3 212.0 483.8 920.3 208.6 228.0 187.2 246.6 234.6 308.8 214.0 258.8 247.6 219.5 290.5 218.5 179.8 169.9 147.6 79.0 458.5 0.0 331.6 0.0 154.8 291.5 247.8 166.2 135.4 261.7 82.3 211.5 123.0 235.9 566.8 142.2 127.2 387.5 629.8 235.9 114.8 170.8 115.3 145.4 128.0 358.9 254.5 181.7 170.7 133.6 223.3 325.7 240.2 273.4 292.0 139.7 157.8 122.0 0.0 448.6 0.0 908.1 218.7 387.9 0.0 60.9 298.5 317.2 358.4 82.9 111.7 250.1 137.0 294.2 505.1 280.7 252.6 289.7 212.1 252.5 177.5 203.7 177.1 194.7 133.9 133.4 0.0 276.9 794.4 167.8 115.9 310.6 LEPROTL1 "my047, Vps55" ENSG00000104660 "Leptin receptor overlapping transcript like 1" O95214 8 30095408-30177208 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047911 Uncertain NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "HPA047911: AB_2680206" "unprognostic (4.42e-2)" "unprognostic (1.33e-2)" "prognostic favorable (9.04e-4)" "unprognostic (1.92e-2)" "unprognostic (3.77e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-3)" "unprognostic (5.24e-2)" "unprognostic (2.44e-1)" "unprognostic (4.73e-3)" "unprognostic (2.30e-1)" "unprognostic (9.44e-3)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.03e-1)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (2.53e-1)" 37.0 48.5 20.0 32.6 20.7 55.7 25.0 23.8 26.0 20.3 16.7 28.4 20.4 21.4 25.6 18.8 21.1 23.5 34.0 22.7 20.3 29.4 38.8 29.7 39.4 19.1 18.9 20.4 22.7 21.8 15.3 75.9 19.6 17.8 26.0 25.7 20.7 22.1 13.3 21.8 26.5 24.0 19.5 33.1 25.3 34.1 19.8 66.3 15.3 14.9 36.1 26.4 17.6 21.8 39.3 48.9 67.8 52.0 36.2 27.4 27.0 55.6 45.1 37.9 60.7 40.4 41.2 24.3 45.6 51.7 47.9 37.6 52.3 39.2 60.8 32.9 31.3 75.0 35.0 74.6 55.9 23.1 55.3 31.5 41.4 42.7 27.0 43.7 47.0 57.4 79.4 40.1 45.3 49.6 52.4 31.4 47.1 73.9 30.8 41.8 27.1 28.9 48.7 48.3 15.4 55.3 30.4 31.2 50.5 44.8 29.0 22.5 41.2 23.0 114.6 19.1 42.8 15.6 24.0 49.3 33.8 49.4 55.0 252.3 119.8 171.3 142.3 121.9 188.3 38.2 246.6 174.7 83.3 33.4 347.3 259.9 229.9 102.3 160.6 115.4 338.9 284.5 20.0 20.7 23.8 26.0 22.7 20.3 19.1 18.9 19.6 19.5 19.8 21.8 97.7 35.3 42.3 13.7 62.2 29.2 16.5 57.5 21.1 23.2 38.6 29.3 40.9 42.9 42.4 42.3 12.5 56.2 196.6 39.1 19.6 113.4 122.2 44.8 40.3 67.2 33.0 30.1 25.2 102.3 105.2 36.4 35.7 34.3 141.4 149.2 69.3 74.9 98.3 20.2 25.6 35.4 67.1 93.1 70.3 79.7 35.4 85.1 62.2 15.9 86.3 27.6 117.4 24.1 21.5 83.9 36.7 26.4 78.0 15.2 48.7 83.1 65.7 26.3 52.6 21.8 71.3 122.6 68.4 31.1 34.7 51.9 351.9 48.2 33.2 19.3 MBOAT4 "FKSG89, GOAT, OACT4" ENSG00000177669 "Membrane bound O-acyltransferase domain containing 4" Q96T53 8 30131671-30144665 "Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pancreas: 3.6;stomach 1: 3.7" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Cholangiocytes: 12.8;Ductal cells: 3.1;Enteroendocrine cells: 3.5;Excitatory neurons: 2.4;Inhibitory neurons: 3.1;Oligodendrocyte precursor cells: 3.0;Oligodendrocytes: 5.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Hep G2: 3.1;OE19: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044509 Supported "Golgi apparatus" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" "HPA044509: AB_2678966" "unprognostic (4.35e-3)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (3.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.76e-2)" "unprognostic (1.85e-3)" "unprognostic (4.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.07e-1)" "unprognostic (6.30e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-6)" "unprognostic (9.87e-3)" "unprognostic (1.58e-1)" "unprognostic (2.18e-1)" "unprognostic (3.66e-2)" 0.1 0.5 0.1 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.1 0.0 0.1 1.7 0.9 0.2 0.1 0.1 0.1 0.4 0.3 0.4 0.1 0.1 0.1 3.6 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.0 0.0 0.4 3.7 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 3.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.1 0.0 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.1 0.1 0.6 0.1 0.4 0.7 0.0 0.4 0.6 0.2 1.0 0.7 1.2 0.8 0.8 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 3.1 1.1 0.0 0.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.0 0.0 3.1 0.0 0.0 0.6 0.0 0.6 0.0 0.2 0.0 1.0 0.0 0.0 0.0 3.0 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 RBPMS HERMES ENSG00000157110 "RNA binding protein, mRNA processing factor" Q93062 8 30384511-30572256 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "ASC diff: 324.1;RPTEC TERT1: 232.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056999 Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Cytosol "HPA056999: AB_2683306" "unprognostic (1.65e-1)" "unprognostic (7.81e-2)" "unprognostic (1.53e-1)" "unprognostic (2.23e-3)" "unprognostic (8.66e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-2)" "unprognostic (3.47e-3)" "unprognostic (4.63e-2)" "unprognostic (2.32e-1)" "unprognostic (4.67e-2)" "unprognostic (2.88e-2)" "unprognostic (1.76e-2)" "unprognostic (4.76e-2)" "unprognostic (2.52e-1)" "unprognostic (4.91e-2)" "unprognostic (2.16e-3)" 238.3 96.7 22.3 43.8 28.0 1.4 194.8 20.2 24.1 196.9 26.7 350.6 25.2 200.7 90.0 99.9 200.5 95.4 174.7 17.3 25.2 218.7 108.9 119.6 23.3 23.1 27.6 190.0 68.8 68.6 33.0 105.0 28.7 182.6 46.6 10.4 92.1 193.7 31.2 56.6 107.7 171.9 18.7 56.7 159.8 45.4 33.2 23.5 140.7 31.6 20.0 323.4 134.0 18.9 0.7 54.5 58.5 0.4 324.1 96.4 145.8 74.8 101.8 90.2 74.6 76.2 31.2 0.5 39.3 96.7 82.5 29.9 68.0 54.4 107.9 0.1 14.6 1.8 24.7 80.5 139.4 0.5 12.0 112.8 13.8 86.7 11.5 100.8 52.8 2.5 0.5 0.4 44.6 32.6 0.3 1.2 150.9 62.3 34.6 3.5 16.2 4.7 232.2 88.9 1.1 11.6 7.7 55.2 37.7 192.3 11.7 0.0 48.8 44.3 4.2 77.3 12.8 0.1 0.2 0.4 72.8 0.2 20.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 22.3 28.0 20.2 24.1 17.3 25.2 23.1 27.6 28.7 18.7 33.2 18.9 104.0 54.5 98.9 36.6 4.5 9.3 61.8 22.7 14.2 6.7 45.8 64.3 114.4 75.8 48.5 141.6 2.1 108.7 4.1 1.8 113.5 100.0 104.7 31.2 86.3 69.7 1.8 5.0 6.4 94.8 184.8 66.7 18.8 48.2 10.1 18.0 44.3 55.2 39.9 0.0 5.2 0.1 20.3 1.9 10.2 31.5 171.2 4.3 14.2 71.2 2.1 1.0 1.0 2.0 1.6 67.0 0.0 180.2 0.5 101.5 2.0 242.2 30.9 5.7 111.7 6.6 149.9 35.3 22.0 27.8 8.0 41.2 4.4 28.1 1.0 151.7 GTF2E2 "FE, TF2E2, TFIIE-B" ENSG00000197265 "General transcription factor IIE subunit 2" P29084 8 30578318-30658236 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004816, CAB009603, HPA025065" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "CAB009603: AB_2114537, HPA004816: AB_2667252, HPA025065: AB_10601658" "unprognostic (4.84e-2)" "unprognostic (7.38e-3)" "unprognostic (6.20e-3)" "unprognostic (9.09e-2)" "unprognostic (6.30e-2)" "unprognostic (4.38e-1)" "unprognostic (6.05e-3)" "unprognostic (8.69e-2)" "unprognostic (2.29e-1)" "unprognostic (4.72e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "prognostic unfavorable (5.82e-7)" "unprognostic (8.25e-2)" "unprognostic (1.72e-1)" "unprognostic (1.05e-3)" "unprognostic (1.24e-1)" 24.5 29.1 14.9 17.8 16.1 9.4 19.9 19.9 19.3 25.1 16.9 20.9 19.5 19.4 17.2 26.4 16.4 13.2 16.2 15.9 17.3 21.4 28.1 17.8 25.9 14.8 15.1 30.3 51.8 15.4 20.1 16.8 15.0 18.7 16.0 11.6 15.9 14.6 13.4 20.6 17.5 18.5 14.7 20.4 24.4 32.7 16.5 22.4 17.4 11.0 26.6 24.1 24.1 15.8 53.7 43.7 29.2 31.2 77.4 68.2 22.0 57.7 52.4 46.5 58.6 26.2 38.2 70.0 48.0 51.9 67.0 37.8 49.1 53.8 61.5 31.8 28.2 34.9 28.9 63.0 75.4 17.1 29.5 50.6 70.7 49.7 50.7 46.3 65.3 51.2 68.7 42.1 74.5 37.3 83.7 42.9 33.1 66.0 51.9 43.2 31.6 35.4 50.9 36.7 22.4 29.1 32.1 21.5 46.5 38.3 20.8 20.9 49.9 30.6 31.4 25.9 39.8 42.6 62.7 77.0 48.2 28.8 41.3 4.3 4.2 6.4 3.6 3.5 4.1 18.8 5.7 7.6 7.3 11.7 5.6 5.5 2.2 9.7 3.7 8.2 7.0 2.8 14.9 16.1 19.9 19.3 15.9 17.3 14.8 15.1 15.0 14.7 16.5 15.8 20.2 0.0 8.4 16.6 48.7 47.9 48.1 44.3 48.3 9.2 19.1 17.5 9.9 17.2 28.2 14.7 10.4 43.0 32.3 26.5 19.6 31.5 96.7 42.2 33.8 22.9 13.2 14.1 30.2 33.1 51.4 30.0 31.1 29.0 11.4 17.7 26.4 27.0 34.1 5.0 30.1 24.2 22.4 21.6 39.3 58.9 39.4 28.4 21.4 13.1 58.8 9.0 46.4 17.1 21.8 43.3 23.4 70.7 35.9 72.7 46.5 48.2 40.0 14.9 26.3 17.5 28.0 74.3 87.9 38.3 46.5 62.1 36.9 26.1 24.5 91.8 SMIM18 ENSG00000253457 "Small integral membrane protein 18" P0DKX4 8 30638580-30646064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 4.4;pituitary gland: 5.4;retina: 3.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 12.3;Excitatory neurons: 2.9;Horizontal cells: 5.0;Inhibitory neurons: 5.2;Microglial cells: 4.7;Oligodendrocyte precursor cells: 5.5;Proximal tubular cells: 4.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 9.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066648 Supported Uncertain Nucleoplasm,Centrosome NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Centrosome "HPA066648: AB_2685697" "unprognostic (2.19e-2)" "unprognostic (9.37e-2)" "unprognostic (3.31e-1)" "unprognostic (4.24e-2)" "unprognostic (1.66e-1)" "unprognostic (2.60e-1)" "unprognostic (7.29e-2)" "unprognostic (4.70e-1)" "unprognostic (8.91e-3)" "unprognostic (1.05e-1)" "unprognostic (2.36e-1)" "unprognostic (6.08e-2)" "unprognostic (4.01e-3)" "unprognostic (1.33e-1)" "unprognostic (3.25e-1)" "unprognostic (4.14e-1)" 0.0 0.9 2.2 0.0 1.9 0.9 0.0 4.0 3.7 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 3.8 0.9 0.0 0.0 0.0 2.3 4.4 0.0 0.4 0.0 5.4 0.0 3.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.7 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.0 0.0 1.2 0.6 0.6 1.1 0.4 1.1 0.9 0.7 0.6 0.3 0.9 0.9 1.3 0.7 0.0 0.8 1.4 1.0 0.1 2.2 1.9 4.0 3.7 2.0 3.8 2.3 4.4 3.0 1.7 2.7 1.6 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.2 0.1 1.8 0.0 2.9 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.9 0.0 5.5 1.1 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported Cytosol NA NA 81000000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" Cytosol "CAB008632: AB_1616690, HPA001538: AB_1078986, HPA064806: " "unprognostic (1.23e-1)" "prognostic favorable (3.37e-4)" "prognostic favorable (4.08e-5)" "unprognostic (2.89e-3)" "unprognostic (1.62e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (3.26e-5)" "unprognostic (3.61e-2)" "unprognostic (1.01e-1)" "unprognostic (4.15e-2)" "unprognostic (2.83e-2)" "unprognostic (6.92e-3)" "prognostic favorable (1.80e-4)" "unprognostic (2.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" 13.6 23.3 12.3 18.7 11.1 25.9 11.0 10.6 11.7 28.5 25.8 42.5 54.3 16.0 21.6 37.3 21.6 30.5 25.4 12.9 12.5 45.3 35.8 17.4 23.6 9.5 14.2 23.1 26.5 82.3 14.8 23.5 12.0 35.3 46.6 12.8 25.8 29.4 28.9 12.8 50.8 17.9 10.7 22.1 41.8 11.6 17.6 26.7 16.9 21.3 24.0 22.5 27.7 11.2 49.4 197.8 35.9 40.1 35.8 38.3 29.1 23.4 46.8 31.8 36.7 66.0 31.3 95.8 94.8 32.0 96.1 59.2 62.3 51.1 33.1 22.6 40.7 104.6 67.0 197.8 88.4 38.6 159.7 72.6 28.5 48.9 20.9 33.5 43.3 57.3 73.2 55.1 67.9 44.1 147.1 32.0 65.4 191.9 31.5 43.8 41.9 59.3 56.0 124.3 28.2 31.8 31.2 87.8 58.8 40.7 37.5 32.6 63.8 21.0 34.7 37.3 35.2 20.2 29.4 70.0 51.9 51.8 62.4 32.3 5.9 15.0 5.0 5.4 8.8 3.6 4.5 5.4 6.0 2.3 2.8 3.7 8.2 3.6 7.9 3.9 4.5 3.1 12.3 11.1 10.6 11.7 12.9 12.5 9.5 14.2 12.0 10.7 17.6 11.2 8.2 3.2 20.8 12.7 13.7 4.2 15.2 9.4 52.3 6.7 6.7 5.0 26.8 30.0 15.0 12.9 16.7 17.0 20.3 61.8 9.8 11.4 8.4 61.4 13.4 9.9 34.1 28.6 18.1 19.8 6.3 10.0 33.1 41.3 6.3 64.3 12.1 43.4 18.2 3.3 27.4 51.7 8.2 40.5 5.8 18.9 7.2 22.1 8.8 11.2 20.6 12.6 17.5 12.5 10.0 15.2 32.0 10.9 15.6 27.5 75.7 19.0 11.7 8.0 6.6 7.0 8.6 1.2 3.4 39.6 5.4 6.4 17.3 17.2 47.5 33.5 UBXN8 "D8S2298E, REP8, UBXD6" ENSG00000104691 "UBX domain protein 8" O00124 8 30729131-30767006 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 79.9" "Group enriched" "Detected in many" 5 "Early spermatids: 167.4;Granulosa cells: 191.2;Hepatocytes: 65.7;Late spermatids: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017725, HPA077538" Enhanced Supported "Nucleoplasm,Nucleoli,Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 1: K-562 - Erythropoiesis" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" "Nucleoplasm, Nucleoli" "HPA017725: AB_1847462, HPA077538: AB_2686844" "unprognostic (3.00e-2)" "unprognostic (2.30e-1)" "prognostic favorable (6.13e-4)" "unprognostic (7.71e-2)" "unprognostic (2.24e-1)" "unprognostic (1.03e-1)" "unprognostic (2.41e-1)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (5.13e-2)" "unprognostic (1.58e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.49e-1)" "unprognostic (1.96e-1)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" 10.2 17.3 17.0 7.1 12.0 8.8 14.1 12.2 16.1 10.4 0.0 12.5 13.1 10.4 49.9 10.7 13.2 13.5 4.9 13.3 5.4 22.1 44.1 8.7 8.1 10.3 4.2 79.9 33.0 20.5 2.8 15.6 10.6 16.3 16.3 11.6 8.5 18.6 3.7 16.9 12.1 10.8 1.7 11.1 12.4 37.1 9.2 14.3 25.9 5.4 9.7 10.4 3.3 12.7 16.4 17.0 11.7 12.2 17.9 25.2 14.3 29.5 17.2 15.2 19.6 27.6 6.1 26.8 23.2 24.5 25.9 14.8 3.1 16.8 24.6 23.9 27.2 77.0 14.0 33.0 27.3 18.1 41.8 20.2 17.4 25.6 12.7 13.6 14.1 12.8 71.9 21.8 35.5 16.1 18.6 14.6 22.9 52.2 12.9 21.4 10.9 18.3 27.7 22.4 6.4 17.7 8.3 26.0 52.1 14.1 16.8 30.4 17.3 17.0 7.8 8.2 28.3 8.8 29.2 19.7 15.0 29.0 25.5 0.0 4.6 0.6 6.2 4.9 5.4 4.7 3.3 5.8 5.2 1.9 3.0 5.5 0.8 2.8 2.4 6.5 3.2 2.7 17.0 12.0 12.2 16.1 13.3 5.4 10.3 4.2 10.6 1.7 9.2 12.7 20.5 3.2 8.2 5.5 5.2 0.0 5.4 0.0 8.0 2.5 7.5 7.6 4.3 17.2 3.1 14.7 20.9 23.8 10.7 7.5 7.9 9.7 167.4 9.1 18.6 12.4 8.5 12.8 5.4 5.3 20.2 22.8 9.7 11.3 14.0 191.2 21.4 65.7 22.0 11.8 7.8 9.7 0.0 16.7 0.0 180.4 14.3 8.9 0.0 6.5 11.6 8.1 12.3 4.5 16.3 3.1 6.0 9.8 6.7 4.9 6.9 25.4 0.7 2.2 6.6 8.7 10.4 16.1 24.2 13.0 0.0 15.2 6.6 27.1 11.8 4.4 PPP2CB PP2Abeta ENSG00000104695 "Protein phosphatase 2 catalytic subunit beta" P62714 8 30774457-30814314 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Peritubular cells: 264.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018600, HPA043236" Approved Supported Nucleoplasm NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB018600: AB_675841, HPA043236: AB_2678379" "unprognostic (9.77e-2)" "unprognostic (1.30e-1)" "unprognostic (2.51e-2)" "unprognostic (3.82e-1)" "unprognostic (6.70e-2)" "unprognostic (7.79e-2)" "unprognostic (1.13e-2)" "unprognostic (3.51e-1)" "unprognostic (2.28e-1)" "unprognostic (2.86e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-2)" "prognostic favorable (5.82e-7)" "unprognostic (9.24e-2)" "unprognostic (2.04e-1)" "unprognostic (1.39e-1)" "unprognostic (2.65e-3)" 89.9 66.6 190.2 42.2 196.1 10.5 68.4 189.1 220.1 84.0 147.9 79.3 72.9 112.1 117.1 95.1 87.8 74.2 94.7 191.6 190.7 131.9 118.6 90.6 32.5 199.7 184.1 147.4 75.7 93.3 52.5 91.0 190.4 74.9 76.2 77.9 68.6 87.1 105.7 63.7 87.0 122.3 195.1 52.9 71.2 64.7 204.4 41.4 126.7 122.7 47.4 76.8 70.0 200.1 96.5 82.7 136.4 54.4 134.6 120.0 78.0 124.0 114.0 123.1 129.5 86.6 68.3 45.6 118.7 165.4 117.9 56.5 84.4 142.1 167.3 28.5 44.2 61.8 52.7 86.9 157.3 28.1 34.2 108.6 157.4 105.2 115.9 124.2 152.5 73.6 97.7 47.6 212.4 48.4 77.1 34.9 102.6 139.3 47.0 53.9 55.7 34.5 168.5 73.6 134.3 55.0 57.8 61.1 127.0 150.5 34.1 47.8 164.0 109.1 81.7 36.1 105.5 24.0 33.6 53.7 93.4 26.0 141.4 3.4 2.5 1.7 1.8 3.1 2.3 2.9 1.7 1.9 1.7 1.1 1.7 2.1 2.3 3.8 1.5 3.8 1.3 0.8 190.2 196.1 189.1 220.1 191.6 190.7 199.7 184.1 190.4 195.1 204.4 200.1 81.0 70.5 60.7 68.6 13.0 104.1 115.9 44.4 44.9 36.6 64.9 51.8 80.2 45.8 54.3 86.5 31.3 41.1 23.6 186.1 46.9 40.6 21.8 98.5 109.8 60.9 32.3 16.6 41.0 48.9 52.8 79.0 34.7 89.2 17.7 95.4 87.8 95.5 58.4 47.1 59.1 65.3 28.5 55.4 60.4 20.3 73.3 36.0 40.9 52.5 27.4 127.2 17.5 37.7 60.4 81.1 78.9 264.0 15.8 125.4 115.6 95.9 68.2 26.5 46.0 93.1 73.0 37.2 40.4 50.3 95.6 70.6 17.4 75.3 41.2 149.9 TEX15 CT42 ENSG00000133863 "Testis expressed 15, meiosis and synapsis associated" Q9BXT5 8 30831544-30913008 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, DNA damage, DNA repair, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "endometrium 1: 6.7;smooth muscle: 5.3;testis: 12.1" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Early spermatids: 114.3;Late spermatids: 49.7;Spermatocytes: 95.4;Spermatogonia: 98.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 8.4;HEL: 19.3;K-562: 5.5;OE19: 4.2;SCLC-21H: 4.1" "Region enhanced" "Detected in single" "olfactory bulb: 2.2" "Low region specificity" "Detected in many" HPA036800 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Cytosol" "HPA036800: AB_10671714" "unprognostic (3.10e-1)" "unprognostic (2.56e-1)" "unprognostic (3.30e-4)" "unprognostic (3.54e-1)" "unprognostic (2.45e-2)" "unprognostic (2.15e-3)" "unprognostic (2.80e-3)" "unprognostic (4.52e-2)" "unprognostic (5.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-5)" "unprognostic (8.88e-3)" "unprognostic (1.39e-1)" "unprognostic (2.09e-1)" "unprognostic (4.92e-1)" 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.3 0.2 0.2 0.4 12.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.9 0.0 8.4 1.1 0.0 1.2 3.1 19.3 0.0 0.3 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 5.5 0.0 0.0 0.1 0.1 0.1 3.7 4.2 0.3 0.0 0.0 0.0 0.0 0.0 4.1 1.3 0.0 0.0 3.6 0.2 0.2 1.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.1 0.4 0.7 0.3 0.3 0.6 0.7 0.2 0.4 0.2 0.1 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 114.3 0.1 1.3 0.5 0.0 0.0 5.7 0.0 0.0 1.2 0.0 0.0 0.0 1.7 2.5 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 49.7 1.2 0.1 0.0 1.0 0.0 1.3 0.0 0.5 0.4 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.0 0.1 13.1 0.0 0.1 95.4 98.5 0.0 0.0 0.1 0.0 4.4 0.0 0.0 PURG "PURG-A, PURG-B" ENSG00000172733 "Purine rich element binding protein G" Q9UJV8 8 30995802-31033715 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;retina: 4.1" "Cell type enhanced" "Detected in some" "Astrocytes: 61.0;Excitatory neurons: 57.2;Inhibitory neurons: 69.5;Late spermatids: 22.0;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 27.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;JURKAT: 4.3;NTERA-2: 4.8;SH-SY5Y: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047746 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" Nucleoli "HPA047746: AB_2680145" "unprognostic (3.37e-1)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (7.33e-3)" "unprognostic (3.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.51e-3)" "unprognostic (1.10e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (4.79e-2)" "unprognostic (8.72e-2)" "unprognostic (1.46e-3)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (1.83e-2)" "unprognostic (5.30e-2)" 0.3 0.4 7.7 0.2 8.3 0.0 0.2 10.5 9.0 1.3 0.5 0.3 0.1 2.0 0.6 0.2 0.4 0.8 0.4 8.7 7.7 0.4 0.0 0.2 0.2 6.6 6.7 0.5 0.0 0.0 3.0 0.2 7.4 0.5 0.1 4.1 0.3 0.6 0.1 0.0 0.2 1.3 6.1 0.6 0.2 2.6 7.3 0.1 0.2 0.2 0.1 0.2 0.8 6.5 0.0 0.0 6.1 0.1 0.0 0.0 0.0 0.1 0.3 0.5 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.0 2.0 0.0 0.7 0.0 3.1 1.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.9 0.0 0.7 3.0 4.3 0.3 0.4 0.1 0.0 0.6 0.0 4.8 0.0 0.2 1.6 0.8 0.0 0.0 0.0 0.8 5.7 0.0 0.0 0.0 2.2 0.0 0.0 1.9 2.0 2.5 0.0 0.3 0.2 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.3 10.5 9.0 8.7 7.7 6.6 6.7 7.4 6.1 7.3 6.5 0.5 0.0 0.0 61.0 0.0 0.0 0.0 0.0 0.0 13.3 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 17.3 0.2 3.2 0.5 0.0 0.0 57.2 0.0 0.0 1.1 0.0 0.1 0.0 3.6 0.0 0.0 0.0 20.2 69.5 0.0 0.0 0.0 0.3 22.0 0.6 0.1 0.0 12.2 0.0 10.8 0.0 49.3 27.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 1.3 4.2 1.5 0.0 0.0 0.0 0.1 1.8 0.0 0.0 WRN "RECQ3, RECQL2" ENSG00000165392 "WRN RecQ like helicase" Q14191 8 31033788-31176138 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Exonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 74.7;Early spermatids: 116.3;Oligodendrocytes: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028661 Approved Supported "Nuclear speckles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "HPA028661: AB_10602255" "unprognostic (8.73e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-3)" "unprognostic (3.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-2)" "unprognostic (2.21e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" "unprognostic (1.27e-2)" "unprognostic (6.63e-2)" "unprognostic (1.53e-2)" "unprognostic (6.51e-2)" "unprognostic (2.49e-1)" "unprognostic (1.00e-2)" "unprognostic (2.66e-1)" 3.0 3.6 1.7 3.2 1.7 8.2 4.8 4.1 2.4 3.0 2.6 3.5 1.5 6.4 3.2 2.7 2.9 2.4 1.7 1.6 1.7 2.1 2.5 2.4 2.5 1.8 2.1 5.2 2.6 2.0 2.1 3.6 1.8 3.5 2.9 4.4 3.5 2.6 2.1 4.1 2.5 4.2 1.2 3.1 2.3 3.0 1.9 3.2 3.2 2.2 3.0 2.6 2.3 3.1 4.4 5.9 10.8 5.3 6.7 9.8 5.0 4.7 4.9 6.4 6.6 2.7 1.5 10.0 4.6 4.3 4.4 2.4 6.4 3.8 9.7 3.3 4.3 9.6 4.9 4.4 5.4 8.7 4.3 7.1 3.7 3.6 6.2 3.9 7.7 6.1 14.5 5.0 6.8 2.0 17.5 6.6 7.7 5.1 3.2 7.5 7.5 6.7 2.9 4.4 3.3 5.2 6.9 2.7 3.8 4.9 2.9 5.3 9.1 6.2 3.8 3.1 4.9 1.4 3.0 14.6 5.5 3.8 4.2 0.8 0.2 0.3 0.3 0.1 0.4 0.5 0.5 0.3 0.2 0.5 0.3 0.4 0.3 1.1 0.1 0.1 0.3 0.1 1.7 1.7 4.1 2.4 1.6 1.7 1.8 2.1 1.8 1.2 1.9 3.1 17.5 9.6 10.6 74.7 15.1 13.5 11.7 5.3 18.8 14.5 14.7 10.5 7.5 15.7 8.8 16.5 22.9 7.1 18.0 5.3 1.9 6.7 116.3 15.8 32.3 12.5 2.4 49.2 59.7 9.8 5.7 15.2 21.9 17.1 2.5 18.5 7.1 9.7 5.3 15.2 54.9 13.8 8.2 5.3 6.6 12.8 19.0 7.8 10.6 51.5 6.9 14.3 4.1 61.3 88.6 9.1 4.2 14.3 16.6 15.3 3.9 2.7 10.0 19.8 6.6 20.2 15.3 10.9 19.2 10.1 10.2 5.6 13.0 15.2 7.7 11.0 NRG1 "GGF, HGL, HRG, NDF, NRG1-IT2" ENSG00000157168 "Neuregulin 1" Q02297 8 31639222-32855666 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.4" "Group enriched" "Detected in many" 17 "Excitatory neurons: 1466.4;Inhibitory neurons: 411.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "classical monocyte: 55.3" "Lineage enriched" "Detected in many" 5 "monocytes: 55.3" "Cell line enhanced" "Detected in many" "A549: 132.5;BJ: 91.3;fHDF/TERT166: 98.1;GAMG: 95.4;U-2197: 84.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010964 Uncertain Approved Nucleoplasm "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA010964: AB_1854641" "unprognostic (5.76e-3)" "unprognostic (8.60e-2)" "unprognostic (1.96e-4)" "unprognostic (2.67e-1)" "unprognostic (1.94e-4)" "unprognostic (4.99e-2)" "unprognostic (6.69e-2)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" "unprognostic (5.65e-2)" "unprognostic (7.99e-2)" "unprognostic (8.49e-2)" "unprognostic (4.47e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (5.40e-2)" "unprognostic (7.83e-2)" 0.5 1.2 3.5 6.1 3.2 1.4 5.7 8.7 13.2 8.0 3.2 3.2 2.9 1.2 0.6 2.8 1.1 2.3 1.9 0.4 12.7 8.6 17.0 3.7 0.4 35.4 8.0 1.9 0.7 0.6 3.8 0.2 35.3 2.6 3.2 11.6 2.6 1.0 0.1 4.9 2.5 1.0 2.7 1.6 2.5 5.3 2.6 0.8 9.9 0.0 2.1 9.4 3.4 8.2 0.4 132.5 1.8 0.0 0.9 2.5 0.2 91.3 60.0 65.3 55.8 0.0 2.9 0.0 16.4 98.1 95.4 76.7 0.3 34.5 69.4 0.2 0.7 1.3 1.8 2.0 0.4 0.1 0.2 1.3 3.4 81.1 74.6 5.7 41.2 0.1 0.0 0.7 24.4 0.1 0.0 0.1 2.5 0.0 0.0 0.1 0.9 0.0 52.9 3.6 3.4 4.0 7.5 0.0 0.1 5.0 0.0 0.3 34.7 50.7 15.8 84.4 53.6 0.1 0.0 0.9 28.2 0.1 6.6 0.2 55.3 0.9 0.2 4.7 0.2 0.1 0.1 0.0 12.1 0.1 0.0 0.0 2.0 0.2 0.2 0.2 0.0 14.2 3.5 3.2 8.7 13.2 0.4 12.7 35.4 8.0 35.3 2.7 2.6 8.2 0.1 38.5 2.7 29.7 0.8 26.0 48.0 5.1 21.1 11.0 4.3 18.2 2.0 8.6 7.9 3.7 8.4 0.0 1.3 0.0 9.8 1.8 41.5 0.1 1.9 5.7 0.0 0.0 1466.4 0.2 0.0 10.5 0.0 0.2 1.3 3.2 7.1 5.3 0.5 28.6 411.8 0.0 2.0 10.2 1.9 23.5 0.3 22.1 1.8 36.5 49.2 5.0 0.0 54.3 19.2 0.9 0.0 0.4 0.0 42.9 0.0 18.7 2.4 3.1 0.0 0.1 9.3 11.3 5.0 3.2 6.1 0.0 0.6 0.0 0.0 6.5 AC083977.1 ENSG00000286131 "Novel protein" 8 32647202-32647390 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 1.2 0.1 0.0 1.0 0.0 1.2 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FUT10 ENSG00000172728 "Fucosyltransferase 10" Q6P4F1 8 33370824-33473146 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 140.0;Early spermatids: 248.8;Late spermatids: 334.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053970, HPA058655" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Endoplasmic reticulum, Golgi apparatus" "HPA053970: AB_2682327, HPA058655: AB_2683789" "unprognostic (6.02e-2)" "unprognostic (4.61e-2)" "unprognostic (2.85e-3)" "unprognostic (6.24e-2)" "unprognostic (1.01e-1)" "unprognostic (4.80e-2)" "unprognostic (5.40e-3)" "unprognostic (6.07e-2)" "unprognostic (2.84e-1)" "unprognostic (2.23e-1)" "unprognostic (9.10e-3)" "unprognostic (2.76e-4)" "unprognostic (3.06e-3)" "unprognostic (1.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-3)" "unprognostic (6.01e-3)" 1.9 2.2 4.3 1.0 4.7 0.8 3.4 4.2 4.2 4.0 2.0 2.5 2.5 3.1 1.2 1.9 3.3 1.8 1.7 3.0 3.3 3.1 2.0 2.4 1.8 4.3 5.5 5.2 2.6 5.1 1.3 3.5 3.3 2.2 2.7 5.2 2.7 2.1 0.6 3.2 2.6 2.9 2.7 1.5 2.3 1.5 4.8 2.9 2.8 1.2 2.2 2.2 2.2 2.5 2.4 4.5 6.8 8.3 10.8 10.8 3.4 4.3 7.1 4.2 5.4 6.3 3.6 2.7 5.1 5.8 3.5 5.9 10.4 4.1 4.1 5.8 3.8 8.6 3.6 7.0 4.9 1.9 2.9 8.0 7.0 1.1 5.4 8.8 8.6 4.4 8.0 3.2 3.9 1.4 6.6 2.8 9.1 6.4 3.0 4.8 5.1 1.4 6.1 5.4 2.4 2.3 2.5 3.7 5.1 7.0 3.8 1.9 6.6 3.2 1.4 8.1 3.6 1.3 2.2 1.8 2.0 5.4 3.4 0.4 0.6 0.7 1.3 0.2 1.4 1.0 0.7 1.2 1.3 0.3 0.8 0.8 0.4 1.6 0.2 0.7 1.7 0.6 4.3 4.7 4.2 4.2 3.0 3.3 4.3 5.5 3.3 2.7 4.8 2.5 4.5 3.2 2.0 140.0 2.5 2.7 2.7 3.4 4.0 2.9 3.7 3.8 2.5 2.8 3.2 3.7 10.4 12.0 3.0 1.5 1.9 4.5 248.8 2.8 5.7 3.8 3.6 3.8 16.3 4.0 7.0 5.8 6.1 3.0 5.7 10.1 5.3 3.6 3.4 3.3 20.2 3.2 4.1 2.2 1.8 334.2 6.8 2.2 1.8 29.0 3.0 29.9 5.2 44.2 16.4 4.0 1.0 4.9 5.0 1.4 5.3 3.0 2.0 11.0 0.0 5.7 4.6 7.0 2.7 5.5 1.7 6.0 2.6 6.5 3.6 1.3 TTI2 "C8orf41, FLJ23263" ENSG00000129696 "TELO2 interacting protein 2" Q6NXR4 8 33473386-33513185 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023523, HPA029823" Approved Enhanced Centrosome NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Centrosome "HPA023523: AB_1845776, HPA029823: AB_10602337" "unprognostic (6.30e-2)" "unprognostic (3.09e-2)" "unprognostic (9.34e-3)" "unprognostic (5.86e-2)" "unprognostic (2.14e-1)" "unprognostic (1.13e-2)" "unprognostic (4.25e-3)" "unprognostic (2.64e-1)" "unprognostic (3.10e-1)" "unprognostic (2.97e-2)" "unprognostic (1.31e-1)" "unprognostic (2.23e-2)" "unprognostic (3.27e-3)" "unprognostic (1.07e-2)" "unprognostic (2.05e-1)" "unprognostic (1.94e-1)" "unprognostic (9.35e-2)" 5.6 6.9 5.0 6.7 5.5 7.9 6.4 6.6 6.2 6.6 5.5 6.1 5.6 6.2 6.5 6.4 6.5 4.7 7.5 4.9 5.5 6.8 7.4 4.6 10.8 5.4 5.4 5.8 4.7 9.6 5.7 5.8 5.6 6.1 6.0 5.5 6.1 5.1 9.1 6.5 5.5 6.1 5.4 7.6 5.5 12.9 5.5 10.6 6.6 6.9 11.4 6.7 6.0 5.8 8.2 15.1 19.6 19.5 14.8 9.7 8.1 12.2 13.7 20.0 19.6 12.4 6.9 23.3 17.8 9.1 17.8 14.2 31.2 14.3 17.6 10.6 10.0 14.5 8.4 12.9 15.9 13.1 13.4 8.2 17.9 14.9 13.3 12.1 17.7 30.2 21.7 17.9 14.1 16.8 39.0 13.2 25.9 23.0 10.4 26.0 15.6 11.1 11.2 8.9 23.5 12.3 11.8 10.9 14.8 17.7 11.2 10.4 10.7 12.4 10.9 13.0 12.0 9.6 10.0 34.2 12.1 13.0 13.5 19.9 20.9 35.8 24.2 24.5 23.6 18.6 21.1 23.3 19.4 22.9 24.1 21.5 23.0 23.3 27.5 14.0 25.2 19.8 5.0 5.5 6.6 6.2 4.9 5.5 5.4 5.4 5.6 5.4 5.5 5.8 5.6 6.4 4.8 5.9 8.3 5.4 7.8 7.7 8.0 6.3 3.9 3.4 0.7 1.5 8.7 7.3 20.9 9.9 5.0 3.5 3.9 9.4 21.9 7.4 9.3 7.0 3.0 15.4 4.7 9.2 9.5 6.1 3.6 7.2 3.8 8.1 3.6 5.5 9.3 6.7 5.0 6.2 6.1 5.5 3.1 4.2 6.8 5.4 5.4 3.7 10.8 6.1 5.2 3.5 5.7 6.3 2.2 7.5 5.2 7.5 5.6 7.7 8.5 11.5 6.6 6.2 5.5 40.4 10.5 5.0 8.1 8.8 6.0 7.7 5.6 4.9 MAK16 "MAK16L, RBM13" ENSG00000198042 "MAK16 homolog" Q9BXY0 8 33485182-33501262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044417, HPA050574" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Vesicles" "HPA044417: AB_2678935, HPA050574: AB_2681181" "unprognostic (2.10e-1)" "unprognostic (1.74e-1)" "unprognostic (8.48e-3)" "unprognostic (2.28e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.00e-4)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (8.04e-2)" "unprognostic (1.20e-1)" "unprognostic (6.74e-2)" "unprognostic (1.47e-1)" 9.9 6.2 4.7 9.3 4.8 9.2 8.9 5.1 5.7 6.6 4.1 5.7 5.4 7.2 5.1 8.0 5.9 6.5 7.0 4.5 6.4 7.2 9.0 5.6 11.1 5.3 6.3 7.5 9.3 5.9 4.5 7.8 5.8 6.1 6.5 4.0 5.6 5.6 8.4 7.4 5.0 7.7 5.3 6.5 5.4 5.6 5.5 8.8 8.5 8.0 10.8 12.2 5.1 6.0 14.1 19.3 13.2 30.6 15.2 18.1 19.9 25.0 16.2 26.4 24.6 28.5 12.0 49.7 23.8 22.1 22.5 18.3 45.6 27.8 35.0 10.8 12.3 46.9 13.2 25.6 22.9 19.3 27.4 19.1 24.8 34.8 40.4 9.4 19.6 33.5 59.5 27.5 22.0 16.1 68.9 22.4 71.4 34.4 13.2 23.9 20.1 22.2 22.2 23.7 33.6 26.7 15.5 21.1 30.4 16.2 14.7 19.5 17.8 24.9 19.3 32.6 28.9 13.8 16.4 50.4 15.3 39.7 27.0 0.0 2.4 0.6 3.2 5.0 3.6 2.0 3.2 2.8 2.9 2.5 4.0 4.3 0.4 4.4 7.9 3.0 2.6 2.3 4.7 4.8 5.1 5.7 4.5 6.4 5.3 6.3 5.8 5.3 5.5 6.0 12.8 16.0 9.7 3.6 12.8 15.6 15.2 5.6 13.1 5.1 7.9 9.0 12.9 10.0 11.3 9.2 2.1 11.5 7.8 3.9 7.9 10.6 1.8 9.8 19.8 12.7 1.8 15.8 5.8 7.8 15.8 15.8 8.2 10.5 9.5 10.8 5.3 7.3 8.7 10.1 6.0 6.7 6.1 5.3 4.7 1.3 9.0 7.8 1.8 2.8 7.7 2.9 10.3 7.1 4.7 11.5 5.0 7.5 12.1 15.3 4.1 10.2 10.5 5.1 6.6 17.6 14.4 13.8 19.2 12.7 14.9 7.5 9.9 13.8 7.4 12.3 RNF122 FLJ12526 ENSG00000133874 "Ring finger protein 122" Q9H9V4 8 33547754-33567128 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 34.7;Glandular and luminal cells: 19.8;Plasma cells: 13.1;Skeletal myocytes: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 83.7;Karpas-707: 53.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003888 Uncertain NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "HPA003888: AB_1079822" "unprognostic (2.36e-2)" "unprognostic (3.13e-1)" "unprognostic (2.09e-2)" "unprognostic (9.19e-3)" "unprognostic (2.46e-1)" "unprognostic (8.78e-3)" "unprognostic (1.71e-2)" "unprognostic (5.46e-1)" "unprognostic (3.33e-1)" "unprognostic (1.82e-1)" "unprognostic (6.95e-2)" "prognostic favorable (5.37e-4)" "prognostic unfavorable (4.50e-7)" "unprognostic (4.45e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.88e-4)" "unprognostic (7.15e-2)" 36.0 15.0 2.4 9.5 2.2 7.4 19.0 13.7 3.6 11.0 2.2 13.5 2.7 10.4 5.4 6.4 29.1 13.4 28.4 2.2 3.0 10.1 7.3 28.9 7.1 4.8 4.1 48.1 5.6 3.4 4.3 3.0 3.6 10.2 5.0 4.9 7.9 2.4 25.8 9.9 10.1 14.7 3.4 12.4 11.1 5.7 4.3 5.9 6.5 5.8 8.8 13.7 12.8 3.2 0.7 4.4 22.3 9.4 2.0 0.6 3.0 1.4 2.1 2.8 4.5 0.7 0.9 10.7 6.8 3.6 3.8 0.8 4.9 2.0 1.5 0.7 83.7 2.2 1.1 6.1 1.2 0.7 16.9 2.1 1.8 1.5 1.1 4.6 9.0 9.2 2.2 53.9 2.3 2.0 9.5 7.2 12.2 3.4 2.5 10.3 4.3 8.5 3.3 1.3 4.3 24.8 1.6 0.6 3.5 7.7 1.0 3.0 5.2 3.8 3.5 7.0 1.6 21.5 13.0 19.5 2.4 2.9 0.6 5.9 1.0 8.9 1.6 5.0 1.4 3.1 0.9 1.1 0.9 4.9 1.5 1.6 7.6 2.0 11.9 16.2 0.7 0.4 2.4 2.2 13.7 3.6 2.2 3.0 4.8 4.1 3.6 3.4 4.3 3.2 34.7 0.0 0.6 0.0 5.3 4.2 0.6 0.2 6.2 0.0 2.6 1.3 5.1 2.8 0.1 0.0 0.0 0.1 8.1 1.9 0.0 2.7 2.2 9.1 3.8 10.1 0.0 4.0 0.8 0.6 0.6 7.3 4.1 19.8 0.0 1.8 5.7 0.1 1.5 0.0 0.9 1.0 0.0 5.9 7.6 0.9 1.5 4.8 0.0 3.7 0.6 0.7 1.0 2.0 0.9 1.0 2.8 1.2 13.1 0.3 0.2 0.8 0.0 1.5 0.0 13.4 6.7 0.0 0.7 2.8 2.0 0.0 3.0 1.2 1.3 1.1 DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 421.3;tongue: 204.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 76.8;Cardiomyocytes: 59.4;Cone photoreceptor cells: 41.7;Enteroendocrine cells: 25.7;Horizontal cells: 25.2;Rod photoreceptor cells: 75.2" "Cancer enhanced" "Detected in some" "glioma: 6.7;pancreatic cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 97.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "HPA018221: AB_2669813" "unprognostic (2.77e-4)" "unprognostic (2.70e-2)" "unprognostic (2.70e-3)" "unprognostic (5.47e-3)" "unprognostic (2.01e-1)" "unprognostic (1.24e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-2)" "unprognostic (2.81e-1)" "unprognostic (1.39e-1)" "unprognostic (4.10e-3)" "unprognostic (1.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-2)" "unprognostic (1.14e-1)" "unprognostic (8.15e-2)" "unprognostic (5.80e-2)" 0.7 27.4 44.2 1.2 45.2 0.2 0.4 47.4 49.6 1.2 18.4 2.8 3.5 1.3 5.6 5.0 3.6 1.2 70.8 45.0 53.0 1.5 0.2 3.3 0.4 39.8 42.1 33.2 3.0 2.0 61.4 0.0 55.2 4.2 1.1 34.1 4.6 0.8 421.3 0.3 2.6 2.7 38.3 0.7 3.9 3.6 44.4 0.8 0.9 204.4 0.8 1.2 1.7 41.1 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 97.7 23.1 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.1 0.1 3.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.2 45.2 47.4 49.6 45.0 53.0 39.8 42.1 55.2 38.3 44.4 41.1 0.0 0.0 0.0 1.3 0.9 0.0 0.2 0.0 0.6 76.8 0.0 0.3 59.4 0.0 0.0 0.0 41.7 0.0 0.0 0.0 21.5 0.4 7.8 0.4 0.1 0.8 25.7 0.0 11.3 0.4 0.0 3.5 0.5 0.1 0.0 1.0 0.4 0.0 0.0 25.2 14.7 0.5 0.0 0.0 0.0 5.2 0.0 0.1 1.8 2.8 0.0 22.8 0.0 12.1 12.0 1.1 0.0 6.0 5.3 0.3 0.0 2.5 0.0 75.2 0.0 10.8 5.2 0.2 0.2 0.0 0.0 0.0 0.6 0.7 0.1 0.1 UNC5D "KIAA1777, Unc5h4" ENSG00000156687 "Unc-5 netrin receptor D" Q6UXZ4 8 35235475-35796550 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.8;intestine: 6.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 638.7;Inhibitory neurons: 768.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.4;renal cancer: 1.0" "Group enriched" "Detected in many" 4 "hypothalamus: 19.8;thalamus: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;HeLa: 2.9;NTERA-2: 8.6;SH-SY5Y: 2.9;SuSa: 2.8;U-251 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042940 Uncertain NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA042940: AB_10959525" "unprognostic (7.88e-2)" "unprognostic (1.28e-1)" "unprognostic (1.41e-2)" "unprognostic (2.29e-1)" "unprognostic (7.60e-2)" "unprognostic (1.87e-1)" "unprognostic (8.47e-2)" "unprognostic (3.82e-2)" "unprognostic (2.04e-1)" "unprognostic (4.13e-2)" "unprognostic (1.99e-1)" "unprognostic (4.48e-8)" "unprognostic (1.34e-1)" "unprognostic (9.15e-2)" "unprognostic (4.28e-1)" 0.0 1.7 1.7 0.0 2.4 0.0 0.0 0.0 3.1 2.3 0.0 0.3 6.0 1.7 0.0 0.0 0.1 0.0 0.0 2.4 19.8 2.1 0.0 0.0 0.0 0.4 1.6 0.0 0.1 0.1 3.3 0.0 0.0 4.8 0.5 4.9 0.0 0.2 0.0 0.0 1.9 0.9 0.0 0.0 0.1 0.7 7.0 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.5 0.2 2.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 0.0 3.1 2.4 19.8 0.4 1.6 0.0 0.0 7.0 0.0 0.0 0.0 0.0 129.6 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.7 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.0 0.1 0.1 0.0 0.0 638.7 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 40.4 768.3 0.7 0.0 0.0 0.0 4.4 0.0 0.0 0.0 42.2 0.0 1.8 0.0 43.2 10.2 0.0 0.0 0.0 0.0 1.8 2.0 0.6 0.0 2.6 0.0 0.0 0.7 0.7 1.2 0.1 0.1 0.0 0.0 0.0 2.6 0.0 KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 7.5" "Group enriched" "Detected in some" 15 "Early spermatids: 61.1;Late spermatids: 24.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 7.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 ZNF703 "FLJ14299, NLZ1, ZEPPO1, ZNF503L, Zpo1" ENSG00000183779 "Zinc finger protein 703" Q9H7S9 8 37695782-37700019 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 108.4" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 434.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "intermediate monocyte: 3.3;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 12 "monocytes: 4.3" "Cell line enhanced" "Detected in many" "HEK 293: 156.8;OE19: 61.2;SK-MEL-30: 60.0;T-47d: 52.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023930, CAB068249" Supported NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "CAB068249: AB_2665667, HPA023930: AB_1859425" "unprognostic (4.64e-2)" "unprognostic (3.15e-2)" "unprognostic (7.01e-3)" "unprognostic (1.71e-3)" "unprognostic (2.54e-1)" "unprognostic (1.42e-1)" "unprognostic (6.93e-2)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-1)" "unprognostic (9.63e-2)" "prognostic unfavorable (2.70e-7)" "unprognostic (5.63e-2)" "unprognostic (1.52e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-1)" 24.6 14.4 16.6 7.6 15.0 1.9 27.4 10.7 16.9 39.9 9.8 46.9 15.1 27.8 12.7 18.2 33.2 6.2 18.8 14.2 10.3 8.1 4.2 10.7 4.1 21.8 17.9 19.6 8.7 1.9 5.9 12.1 16.4 21.7 12.6 0.4 18.3 8.7 108.4 57.4 25.9 11.6 15.0 18.9 22.8 2.9 14.7 2.8 10.6 33.3 2.9 36.8 28.7 10.7 3.2 6.6 0.8 5.2 15.1 7.9 5.2 29.1 13.6 8.8 7.4 27.2 36.0 0.0 7.2 18.4 4.0 17.2 3.0 4.4 6.8 0.8 156.8 0.0 9.5 17.5 14.9 0.0 3.0 26.6 8.2 9.1 3.7 19.0 7.8 0.3 0.4 0.0 14.1 27.4 0.1 0.8 2.6 61.2 11.6 2.7 4.7 3.7 2.7 14.2 2.9 0.2 5.4 4.6 60.0 6.2 52.6 3.1 23.1 10.3 23.7 16.1 12.3 1.9 0.1 0.2 9.1 3.2 6.7 0.0 0.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.1 16.6 15.0 10.7 16.9 14.2 10.3 21.8 17.9 16.4 15.0 14.7 10.7 11.9 6.4 0.0 14.7 15.3 48.2 13.2 28.9 103.0 3.7 39.3 27.8 9.1 2.8 14.5 5.5 0.0 41.4 7.7 52.0 3.9 7.1 0.4 30.8 37.0 9.5 79.6 0.0 1.5 2.5 37.2 36.0 14.8 20.3 0.0 5.8 2.5 2.2 36.2 0.0 2.8 95.4 10.2 23.6 31.9 0.7 31.4 31.2 33.8 11.2 7.9 9.3 0.0 0.0 0.6 3.7 56.9 15.8 1.9 9.7 35.4 2.8 7.7 0.9 52.6 54.9 66.4 0.0 0.6 99.7 74.6 434.1 6.0 6.1 92.6 10.7 ERLIN2 "C8orf2, Erlin-2, NET32, SPFH2, SPG18" ENSG00000147475 "ER lipid raft associated 2" O94905 8 37736601-37758422 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002025, CAB014894" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum" "CAB014894: , HPA002025: AB_1080077" "unprognostic (5.82e-3)" "unprognostic (2.45e-1)" "prognostic favorable (5.16e-4)" "unprognostic (1.08e-2)" "prognostic unfavorable (4.51e-4)" "unprognostic (3.39e-2)" "unprognostic (1.89e-1)" "unprognostic (3.77e-2)" "unprognostic (6.67e-2)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.78e-3)" "prognostic favorable (6.67e-6)" "unprognostic (4.78e-2)" "unprognostic (2.83e-1)" "unprognostic (3.43e-1)" "unprognostic (2.33e-1)" 20.3 17.8 15.7 14.6 17.3 14.4 25.0 16.5 16.8 20.0 27.2 24.2 17.7 21.2 32.3 17.9 30.1 19.8 17.8 14.2 16.3 40.4 40.8 15.5 11.5 18.0 18.5 30.8 26.2 41.4 8.3 21.2 17.7 25.4 25.0 21.6 29.4 23.8 18.9 15.3 23.6 19.5 17.9 14.6 24.9 17.0 15.6 14.7 46.5 14.1 12.6 16.8 10.3 18.6 39.0 38.5 43.0 31.4 47.3 33.9 47.2 59.1 51.9 31.8 33.2 20.1 50.8 18.9 95.8 63.4 30.3 41.4 31.2 48.4 46.8 11.2 24.2 27.8 22.7 22.7 31.5 17.8 34.1 43.3 49.1 46.3 48.1 39.6 30.7 17.2 51.1 17.7 47.4 18.3 25.8 14.7 45.9 53.8 17.7 17.9 29.9 15.2 42.8 41.9 7.7 20.7 39.3 12.6 35.6 50.1 62.0 27.1 31.1 30.9 26.4 56.8 31.1 24.3 41.0 24.2 55.0 28.4 40.7 1.3 6.5 13.4 4.4 7.0 3.6 4.5 2.7 3.5 5.4 2.3 4.1 3.8 6.1 2.5 9.6 7.6 5.5 3.1 15.7 17.3 16.5 16.8 14.2 16.3 18.0 18.5 17.7 17.9 15.6 18.6 14.7 12.8 14.3 21.5 7.1 9.7 10.0 18.5 13.1 25.2 24.9 20.7 30.2 25.8 22.8 33.1 20.9 17.9 6.0 19.0 9.8 23.8 21.3 31.3 18.5 13.6 11.4 8.0 3.7 22.1 27.0 18.8 17.3 27.8 3.8 14.4 17.5 41.0 20.6 16.8 6.4 24.3 20.3 23.9 6.6 16.8 11.8 16.1 14.2 7.5 12.3 23.5 5.2 11.6 16.7 18.8 17.4 17.7 16.8 15.2 25.4 19.8 47.6 18.7 19.7 19.1 14.8 47.4 18.5 21.9 7.4 15.7 7.1 12.9 25.4 12.8 PLPBP PROSC ENSG00000147471 "Pyridoxal phosphate binding protein" O94903 8 37762595-37779768 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 101.8;Exocrine glandular cells: 49.8;Hofbauer cells: 47.3;Proximal tubular cells: 82.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017033, HPA023646, HPA023733" Approved Enhanced Cytosol NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "CAB017033: , HPA023646: AB_1855741, HPA023733: AB_1855742" "unprognostic (1.55e-2)" "unprognostic (2.17e-2)" "unprognostic (2.14e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-2)" "unprognostic (2.36e-1)" "unprognostic (7.78e-3)" "unprognostic (1.80e-1)" "unprognostic (4.28e-2)" "unprognostic (2.83e-2)" "unprognostic (2.59e-2)" "unprognostic (9.41e-3)" "unprognostic (3.16e-2)" "unprognostic (3.99e-2)" "unprognostic (2.90e-1)" "unprognostic (7.85e-2)" 34.2 23.1 22.2 21.2 24.3 14.6 23.3 25.3 27.1 22.1 26.8 47.2 34.5 19.2 23.3 20.2 27.5 19.1 39.2 24.0 25.0 58.5 78.2 25.7 25.0 22.8 24.9 24.7 40.3 37.4 16.2 20.1 23.7 20.2 37.9 10.9 28.3 27.8 46.4 17.0 37.3 25.9 23.7 25.0 33.5 8.4 24.5 27.4 31.8 42.1 29.0 22.9 16.1 28.6 50.3 45.4 35.1 32.0 25.9 31.1 31.6 55.2 45.8 34.7 38.9 51.6 24.3 58.4 61.9 39.9 55.5 41.4 65.4 52.5 56.6 49.9 34.3 79.4 16.4 51.7 51.6 36.8 52.5 22.9 49.8 33.0 52.0 37.6 52.3 78.3 42.8 42.1 28.7 34.8 116.4 32.4 43.0 92.8 41.9 73.6 46.6 34.8 56.5 60.0 21.5 25.1 45.4 20.0 56.8 25.4 44.2 48.6 52.1 19.1 60.7 69.8 38.1 43.3 90.9 43.0 27.4 51.8 35.0 164.3 109.6 136.1 85.6 130.0 90.0 77.8 87.8 83.6 115.2 61.9 77.0 74.3 46.9 75.9 147.4 66.5 116.7 110.2 22.2 24.3 25.3 27.1 24.0 25.0 22.8 24.9 23.7 23.7 24.5 28.6 35.9 9.6 26.5 0.0 6.7 0.0 0.0 0.0 0.0 0.0 27.8 23.0 0.0 0.0 8.1 31.3 0.0 21.2 20.0 0.0 101.8 38.2 0.0 12.8 20.7 13.5 0.0 0.0 0.0 49.8 31.6 13.9 0.0 19.6 12.6 14.8 0.0 0.0 47.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 11.9 0.0 0.0 0.0 0.0 33.2 0.0 0.0 1.8 0.0 0.0 82.2 13.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 12.9 9.8 17.1 0.0 0.0 ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 30.6;Endometrial stromal cells: 49.4;Fibroblasts: 36.4;Hepatic stellate cells: 31.4;Leydig cells: 56.5;Microglial cells: 24.4;Muller glia cells: 25.0;Peritubular cells: 41.8;Sertoli cells: 46.0;Smooth muscle cells: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 83.6;ASC TERT1: 64.8;BJ hTERT+: 75.2;fHDF/TERT166: 77.6;HSkMC: 39.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012393 Uncertain NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" 29.1 4.8 10.0 12.2 8.6 2.0 26.4 8.7 10.1 59.8 5.9 24.1 7.7 45.1 18.2 24.8 43.8 26.2 17.6 9.8 6.5 9.6 4.3 16.2 7.7 7.7 8.3 35.9 5.5 2.2 10.0 48.7 7.8 44.4 8.2 6.7 9.0 54.9 6.6 13.1 12.8 27.8 7.0 11.9 12.3 3.5 11.2 5.2 11.3 8.3 5.6 39.6 32.0 6.6 0.2 2.3 0.3 4.7 83.6 64.8 0.6 38.5 75.2 4.6 12.4 0.5 0.2 0.0 6.9 77.6 3.1 0.9 3.5 0.2 1.5 1.6 1.8 0.2 2.2 0.2 38.1 0.0 0.0 39.4 0.4 3.4 0.8 3.3 22.3 3.0 0.2 0.7 1.2 1.2 0.1 8.0 3.5 0.0 0.6 6.5 4.2 0.4 0.0 0.1 0.3 18.1 1.0 0.2 5.7 17.7 0.2 16.9 18.2 7.6 9.6 11.2 3.5 6.2 0.5 0.1 1.0 20.3 8.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 8.6 8.7 10.1 9.8 6.5 7.7 8.3 7.8 7.0 11.2 6.6 30.6 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 1.0 1.0 1.1 1.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 1.9 0.1 0.2 1.5 49.4 17.8 0.0 0.0 7.8 1.6 0.6 36.4 0.0 2.2 0.0 0.1 31.4 0.1 2.1 0.0 7.8 0.2 0.0 1.6 0.0 3.1 56.5 1.5 0.0 24.4 1.0 25.0 1.0 3.0 0.8 0.3 0.1 41.8 0.1 0.3 0.0 0.0 0.0 0.7 46.0 5.5 36.0 0.3 0.8 0.5 0.0 2.3 0.4 2.6 0.3 0.2 BRF2 "BRFU, FLJ11052, TFIIIB50" ENSG00000104221 "BRF2 RNA polymerase III transcription initiation factor subunit" Q9HAW0 8 37843268-37849861 "Predicted intracellular proteins" "Stress response, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019269, HPA023378" Supported Supported Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoli "CAB019269: , HPA023378: AB_1845446" "unprognostic (9.85e-3)" "unprognostic (2.74e-1)" "unprognostic (2.95e-2)" "unprognostic (2.00e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-3)" "unprognostic (3.91e-2)" "unprognostic (2.35e-2)" "unprognostic (9.68e-2)" "unprognostic (3.31e-1)" "unprognostic (2.11e-1)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (2.52e-3)" "unprognostic (1.33e-1)" "unprognostic (1.93e-1)" "unprognostic (7.41e-2)" 12.0 8.0 6.6 4.6 7.2 14.3 11.0 6.6 7.6 15.2 6.4 11.3 4.1 12.6 6.3 8.2 11.9 4.6 10.8 7.8 6.7 9.8 7.9 7.6 6.7 6.9 7.1 12.8 8.4 6.5 9.7 7.6 7.7 13.7 5.3 5.9 7.9 7.0 28.5 11.2 7.7 5.7 6.6 9.8 8.9 7.8 7.1 11.0 7.2 12.8 5.4 14.0 10.7 7.4 13.1 9.9 9.6 12.4 13.0 9.5 11.2 15.1 12.0 20.1 13.7 12.9 9.2 16.0 21.3 9.6 7.6 13.3 12.5 9.5 10.0 10.0 12.5 19.7 8.3 10.6 13.6 7.9 11.3 12.8 12.3 20.1 8.5 9.8 6.6 14.0 24.6 13.9 6.6 7.5 25.2 9.9 16.1 9.6 13.1 14.7 10.4 8.1 7.4 8.7 8.1 9.7 7.1 10.5 18.3 11.6 22.1 15.0 8.8 10.0 13.7 25.5 15.4 16.5 24.8 18.8 14.5 10.3 18.2 13.9 10.1 11.7 13.5 9.5 13.7 14.2 14.3 13.8 7.9 14.9 20.3 16.6 4.2 20.0 8.7 9.5 13.7 11.7 6.6 7.2 6.6 7.6 7.8 6.7 6.9 7.1 7.7 6.6 7.1 7.4 6.9 12.8 4.8 2.0 4.2 4.5 4.2 6.4 0.6 9.8 6.9 7.5 0.3 7.2 4.7 9.2 0.0 22.6 6.2 5.5 7.9 8.7 0.4 14.2 7.9 7.8 6.6 8.6 3.3 11.0 10.4 8.1 5.6 24.7 2.5 8.6 6.8 2.1 11.6 8.4 3.1 8.6 8.2 7.1 5.4 1.4 9.3 3.9 3.6 1.0 7.1 11.4 10.3 2.5 2.3 6.5 2.2 10.5 7.2 4.3 9.3 5.8 7.1 6.9 6.6 5.5 7.5 12.5 12.4 4.6 3.8 14.1 7.5 11.5 7.2 3.0 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 798.0;Endometrial ciliated cells: 622.9;Glandular and luminal cells: 969.7;Urothelial cells: 613.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 101.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 73.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 7.5 5.7 3.8 17.7 2.7 58.5 21.8 3.8 3.8 14.5 39.3 40.7 41.3 5.9 14.8 47.1 16.9 21.7 12.0 4.4 4.3 13.7 7.2 74.0 17.2 3.4 2.7 4.6 42.5 12.0 8.6 25.8 2.1 8.7 47.0 6.1 23.8 13.5 4.6 18.9 53.5 7.1 2.3 12.0 45.5 6.4 4.0 15.4 13.0 2.7 31.1 23.6 14.9 2.2 41.8 18.1 1.9 8.0 0.4 0.1 54.1 4.2 6.6 7.5 9.6 40.6 23.2 17.0 12.7 5.1 0.4 31.6 14.5 9.4 11.3 44.2 13.5 3.3 9.0 11.9 20.9 7.3 36.3 4.8 12.2 2.8 7.9 11.1 0.1 22.2 73.1 8.2 3.8 9.9 12.4 10.7 12.0 40.9 5.3 3.9 9.7 13.2 39.4 42.2 7.4 8.5 10.6 52.3 13.0 36.8 35.2 14.0 0.6 0.2 23.1 0.6 0.7 16.5 20.7 4.5 0.3 9.8 5.7 24.0 20.5 38.1 4.4 9.4 9.9 6.0 3.2 3.1 18.3 3.8 2.0 2.2 101.9 10.9 20.2 11.0 7.7 10.7 3.8 2.7 3.8 3.8 4.4 4.3 3.4 2.7 2.1 2.3 4.0 2.2 7.6 798.0 112.9 1.0 128.5 15.9 113.5 49.5 24.5 5.4 113.6 58.5 15.8 84.4 228.0 64.4 16.7 44.9 123.6 385.5 15.6 170.2 0.9 622.9 71.4 25.3 243.7 3.8 7.9 248.9 8.1 28.7 272.7 969.7 30.4 2.8 32.2 15.3 32.1 6.7 8.6 312.3 95.6 59.1 174.7 1.8 1.8 121.1 16.0 2.8 95.2 18.6 120.5 0.0 1.0 364.6 299.1 1.5 48.2 192.7 331.9 16.5 348.8 21.0 6.6 9.0 23.3 2.4 5.2 124.2 30.5 96.0 83.8 2.8 256.6 613.9 GOT1L1 MGC33309 ENSG00000169154 "Glutamic-oxaloacetic transaminase 1 like 1" Q8NHS2 8 37934281-37940124 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 14.1" "Cell type enriched" "Detected in some" 5 "Early spermatids: 137.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA028778 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA028778: AB_10602138" "unprognostic (6.93e-3)" "unprognostic (5.46e-1)" 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 137.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 24.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC144573.1 ENSG00000285880 "ADRB3-GOT1L1 readthrough" 8 37934340-37965953 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061969 Uncertain NA NA "HPA061969: AB_2732674" 0.1 0.1 0.3 0.1 0.1 0.2 0.1 0.5 0.4 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.5 0.4 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.1;ovary: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.8;Hofbauer cells: 1.1;Langerhans cells: 1.2" "Not detected" "Not detected" "Region enhanced" "Detected in many" "medulla oblongata: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 33: Fibroblasts - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" 0.3 0.0 1.2 0.4 1.1 0.2 0.3 0.5 0.9 0.4 1.5 2.1 0.2 0.7 1.1 0.1 4.1 1.7 0.0 0.9 0.7 0.0 0.0 0.1 0.1 8.1 2.7 11.7 0.0 0.0 0.0 2.9 3.1 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.0 2.1 0.0 1.8 0.0 0.0 0.0 0.0 4.6 0.4 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.1 0.5 0.9 0.9 0.7 8.1 2.7 3.1 0.4 1.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.6 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 188.9;salivary gland: 164.2" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 730.0;Pancreatic endocrine cells: 277.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 44000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Cytosol" "CAB005032: AB_562030, CAB005039: AB_562029, HPA023501: AB_1848095" "unprognostic (1.55e-2)" "unprognostic (2.45e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (8.86e-4)" "unprognostic (6.94e-2)" "unprognostic (2.69e-1)" "unprognostic (1.94e-2)" "unprognostic (3.27e-2)" "unprognostic (1.61e-1)" "unprognostic (1.16e-2)" "unprognostic (3.18e-3)" "unprognostic (7.21e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (7.98e-2)" "unprognostic (3.01e-1)" "unprognostic (4.57e-2)" "unprognostic (5.72e-3)" 60.9 12.6 7.7 16.9 8.0 35.0 53.6 8.0 10.9 24.9 12.7 25.3 18.5 19.7 2.2 86.0 21.7 8.9 32.7 8.0 9.8 19.5 63.5 25.0 10.3 9.8 8.5 22.2 188.9 7.8 9.2 28.6 9.8 19.2 15.4 1.5 164.2 17.0 98.1 20.8 23.1 14.4 8.5 23.9 43.8 5.5 10.1 9.6 9.6 27.2 10.4 33.6 26.5 10.8 146.9 113.2 32.4 193.2 41.3 32.3 77.0 130.5 111.9 128.4 203.5 74.8 56.3 46.3 101.5 121.3 77.1 85.1 109.1 197.5 74.8 36.0 190.9 269.6 52.0 104.9 423.6 98.8 60.4 100.0 314.9 142.0 264.1 40.1 208.2 57.7 152.7 221.8 54.8 141.7 95.9 297.8 186.0 112.9 243.7 80.3 80.4 197.4 49.3 22.3 281.6 200.8 26.1 78.8 534.8 20.3 105.8 192.2 105.2 76.1 167.1 179.9 137.8 185.1 121.6 72.1 173.4 213.4 169.1 51.1 416.3 258.3 27.9 336.6 27.3 130.7 32.8 30.9 335.0 103.3 26.2 26.0 39.4 35.0 268.3 242.6 66.0 258.3 7.7 8.0 8.0 10.9 8.0 9.8 9.8 8.5 9.8 8.5 10.1 10.8 23.6 9.6 8.3 1.6 25.2 74.4 42.4 114.8 51.8 3.6 84.8 72.8 41.7 57.2 97.3 20.2 2.1 41.3 27.3 70.1 29.4 226.1 17.0 11.6 39.0 54.6 40.2 79.9 0.8 730.0 224.2 68.6 35.7 12.5 18.4 76.0 65.3 103.4 223.4 0.0 1.3 138.2 79.3 108.6 82.2 106.2 43.5 83.9 72.9 1.9 101.9 19.2 21.6 4.0 0.4 277.9 64.5 19.2 38.7 100.2 19.5 103.1 33.5 2.2 13.1 17.6 85.2 1.9 25.5 209.3 85.4 38.6 19.8 69.3 83.8 58.9 ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042289: AB_10795608" "unprognostic (9.39e-2)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (5.40e-3)" "unprognostic (2.87e-1)" "unprognostic (2.66e-2)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (9.73e-3)" "prognostic favorable (4.25e-4)" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.54e-1)" 28.9 18.9 19.7 17.9 20.3 31.6 21.4 19.2 21.5 19.9 14.7 22.5 18.2 22.0 17.1 23.8 20.1 17.4 21.3 20.2 17.4 23.3 23.6 18.5 27.9 16.7 16.1 26.2 17.7 24.8 12.0 22.1 16.7 19.9 22.3 21.7 20.6 21.0 32.4 20.4 18.3 24.2 16.5 18.9 22.1 41.3 19.0 33.6 21.1 27.7 28.3 18.5 16.1 18.1 45.6 23.3 39.8 39.8 26.3 34.0 49.8 44.1 45.7 53.5 47.0 24.9 21.1 51.4 38.2 37.1 27.2 27.5 49.0 24.8 50.4 20.3 22.4 200.3 22.9 51.7 39.4 32.0 41.3 28.6 22.9 25.0 27.7 28.1 43.9 48.0 138.2 40.0 53.7 26.1 91.9 40.7 51.7 39.3 15.6 38.2 42.9 23.4 28.9 33.1 18.3 32.4 33.5 22.5 38.4 37.1 27.4 40.4 33.5 35.3 35.0 50.4 37.6 37.8 48.7 44.9 35.2 44.7 49.7 39.9 23.0 55.9 16.8 26.8 18.1 19.6 18.8 20.0 27.7 19.2 19.3 18.4 19.2 26.1 25.8 15.8 21.3 21.6 19.7 20.3 19.2 21.5 20.2 17.4 16.7 16.1 16.7 16.5 19.0 18.1 11.1 12.8 15.8 18.3 14.3 6.9 9.3 13.3 10.8 12.9 9.6 8.0 18.1 8.6 15.9 12.9 10.4 37.0 15.9 11.5 7.9 21.2 10.8 12.7 13.2 14.0 10.8 62.1 19.7 28.7 37.2 17.3 8.6 10.8 19.6 38.2 12.8 11.9 24.2 6.7 21.4 11.6 12.2 17.2 5.7 13.0 23.3 17.0 23.2 15.9 29.2 17.8 19.6 17.6 16.5 21.3 8.9 20.7 8.4 6.2 12.8 17.1 18.0 15.5 13.1 14.6 20.7 69.6 33.9 11.6 6.8 30.9 11.9 37.3 10.9 7.4 STAR STARD1 ENSG00000147465 "Steroidogenic acute regulatory protein" P49675 8 38142700-38150992 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Steroidogenesis, Transport" "Congenital adrenal hyperplasia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "adrenal gland: 5073.8" "Cell type enriched" "Detected in some" 44 "Theca cells: 2243.4" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.0;lung cancer: 0.8;ovarian cancer: 1.4;testis cancer: 3.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "basophil: 2.4" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.4" "Cell line enriched" "Detected in some" 5 "K-562: 436.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023644, HPA027318, CAB032598" Enhanced NA NA "Cluster 10: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "CAB032598: AB_2115937, HPA023644: AB_10598916, HPA027318: AB_10601574" "unprognostic (1.60e-4)" "unprognostic (3.20e-2)" "unprognostic (9.17e-2)" "unprognostic (3.28e-2)" "unprognostic (9.22e-2)" "unprognostic (1.32e-3)" "unprognostic (1.96e-2)" "unprognostic (2.12e-5)" "unprognostic (3.30e-2)" "unprognostic (2.36e-1)" "unprognostic (1.77e-3)" "unprognostic (6.65e-2)" "unprognostic (4.75e-9)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (9.48e-2)" "unprognostic (6.16e-2)" 1.7 5073.8 2.3 3.1 1.6 2.1 0.4 1.6 3.3 1.0 0.7 0.5 0.2 0.5 0.6 2.1 6.3 0.2 0.9 1.5 4.5 0.4 1.2 0.5 0.9 3.8 3.3 497.1 0.9 0.0 2.2 0.5 4.1 0.5 0.1 0.6 1.8 0.3 0.4 5.0 0.6 0.4 1.4 1.0 0.7 88.2 3.0 3.0 0.4 0.0 1.9 0.5 3.2 1.5 0.1 0.0 0.8 0.2 0.3 3.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 88.9 0.8 5.3 1.3 3.8 0.1 12.4 0.3 0.1 0.1 0.8 0.0 0.3 436.1 0.2 0.0 0.0 0.4 43.7 9.6 0.1 0.1 0.0 0.0 0.0 0.0 0.2 1.2 1.2 0.2 0.0 0.2 0.0 0.1 43.0 1.5 0.1 0.0 0.2 0.1 0.2 0.2 0.0 0.3 9.3 0.2 2.4 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.2 0.0 2.3 1.6 1.6 3.3 1.5 4.5 3.8 3.3 4.1 1.4 3.0 1.5 0.0 0.0 0.0 0.7 0.1 9.4 0.7 0.8 4.0 1.1 0.1 1.1 0.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.9 10.7 0.6 0.0 0.0 1.4 0.0 0.0 25.7 0.0 0.3 0.0 1.4 0.0 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.7 10.2 50.1 0.2 3.6 0.0 0.0 0.6 0.0 0.5 0.3 0.1 0.0 4.1 0.0 0.2 0.0 0.0 0.4 0.6 0.0 0.2 3.0 4.8 0.8 1.7 11.2 0.1 0.1 2243.4 0.0 0.1 LSM1 "CASM, YJL124C" ENSG00000175324 "LSM1 homolog, mRNA degradation associated" O15116 8 38163335-38176730 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024601 Approved "Cytosol,Cytoplasmic bodies" NA NA 22000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Cytoplasmic bodies" Cytosol "HPA024601: AB_1853379" "unprognostic (1.19e-2)" "unprognostic (7.21e-2)" "unprognostic (1.94e-2)" "unprognostic (9.59e-2)" "unprognostic (7.26e-2)" "unprognostic (1.69e-1)" "unprognostic (2.08e-3)" "unprognostic (2.18e-2)" "unprognostic (1.95e-2)" "unprognostic (2.48e-2)" "unprognostic (1.07e-2)" "unprognostic (1.16e-2)" "unprognostic (3.47e-2)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (8.75e-2)" "unprognostic (2.97e-1)" 30.0 31.9 42.1 27.6 43.0 34.4 28.0 44.1 49.2 25.1 43.4 31.0 25.3 27.5 39.6 27.5 22.9 26.7 61.1 41.5 44.0 36.1 36.7 20.4 33.9 42.8 43.2 20.0 28.3 29.5 22.1 34.6 43.0 27.3 29.4 21.4 32.4 34.1 34.8 24.7 25.4 31.7 43.0 22.4 27.0 20.9 44.1 34.8 28.7 35.0 31.8 37.8 22.5 43.2 66.8 72.1 47.6 54.2 78.1 71.8 41.2 78.6 81.9 74.9 78.3 51.3 45.7 32.2 69.4 96.9 75.3 33.1 61.2 67.0 83.7 49.0 71.8 102.9 52.2 65.4 68.1 36.4 65.3 70.1 60.9 62.0 51.2 57.1 66.1 65.0 83.2 78.7 94.7 66.7 110.7 70.4 68.7 100.9 73.9 53.2 49.2 38.1 102.9 78.8 80.3 67.1 34.3 51.0 98.7 48.3 43.3 76.2 65.1 63.9 77.1 96.0 65.0 82.2 123.2 66.2 74.8 73.7 67.3 161.5 65.7 105.0 58.6 75.0 61.1 59.8 64.6 64.9 66.0 52.4 58.4 67.2 50.5 62.9 78.8 111.1 82.1 78.8 42.1 43.0 44.1 49.2 41.5 44.0 42.8 43.2 43.0 43.0 44.1 43.2 40.8 12.8 24.6 5.2 49.5 66.3 45.6 101.7 26.2 26.6 58.5 42.4 5.9 48.6 61.7 68.0 10.4 109.3 78.4 40.7 180.0 90.6 9.0 65.0 47.1 42.9 46.7 36.2 9.3 119.2 138.9 40.7 25.5 53.0 24.1 29.5 42.5 58.5 84.9 13.5 11.6 48.8 75.3 51.5 46.9 8.4 61.5 58.6 48.0 12.2 104.8 55.0 125.7 7.5 12.4 120.0 54.5 56.8 57.1 92.1 59.8 121.4 51.1 24.1 52.6 39.0 58.0 64.7 129.3 40.8 70.3 102.2 57.8 67.3 49.9 87.3 BAG4 SODD ENSG00000156735 "BAG cochaperone 4" O95429 8 38176533-38213301 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013716, HPA018951" Approved NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "CAB013716: , HPA018951: AB_1845260" "unprognostic (2.25e-1)" "unprognostic (3.82e-2)" "unprognostic (1.22e-1)" "unprognostic (5.23e-2)" "unprognostic (4.44e-2)" "unprognostic (7.27e-2)" "unprognostic (3.20e-1)" "unprognostic (2.77e-2)" "unprognostic (1.13e-1)" "unprognostic (5.66e-2)" "unprognostic (2.50e-3)" "unprognostic (4.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.28e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (1.70e-2)" 10.3 5.7 10.8 5.9 12.5 28.6 7.8 10.8 17.8 7.3 3.3 5.5 5.8 6.7 6.8 6.7 5.2 5.5 4.9 13.6 9.0 9.6 16.8 5.7 7.3 9.0 7.5 11.0 5.2 8.0 4.6 11.4 9.0 7.5 5.8 9.6 6.7 7.8 14.4 7.3 5.6 6.0 4.8 6.5 5.5 4.3 10.0 7.5 6.8 6.8 7.6 6.3 5.6 9.8 16.3 18.4 14.9 22.7 27.8 18.5 13.8 16.5 20.3 17.6 19.4 19.0 9.5 19.5 18.1 14.2 11.9 16.4 25.0 14.4 24.2 9.0 14.0 32.8 10.6 27.3 14.0 15.3 13.4 15.5 16.1 18.4 17.7 12.1 10.1 14.0 34.8 11.5 14.7 9.7 27.3 18.0 32.5 12.7 8.2 18.9 17.7 8.9 16.1 17.8 11.4 15.6 13.7 8.9 13.5 13.4 10.7 9.0 14.4 16.3 16.9 27.6 11.1 10.4 16.5 22.9 9.7 17.4 17.2 17.1 13.9 15.1 8.2 11.6 9.7 7.5 7.2 7.9 12.5 7.4 9.3 8.6 8.7 5.6 21.3 6.5 8.4 9.4 10.8 12.5 10.8 17.8 13.6 9.0 9.0 7.5 9.0 4.8 10.0 9.8 10.6 12.8 12.4 15.3 14.7 43.1 13.2 12.7 38.1 18.9 13.1 10.8 11.1 12.8 12.1 20.2 27.1 23.5 10.8 10.4 17.6 11.0 4.0 13.5 14.6 10.9 5.4 19.4 30.6 11.6 19.0 16.2 13.7 16.0 7.6 11.4 12.8 25.5 24.5 13.5 27.5 8.9 6.1 26.7 30.8 4.4 15.2 19.4 37.4 13.1 23.9 10.4 9.2 7.5 20.8 9.1 8.3 13.2 20.6 19.2 15.3 21.1 10.9 11.8 6.6 16.1 12.7 13.3 11.5 24.0 33.8 12.2 14.8 15.7 12.0 18.7 DDHD2 "KIAA0725, SAMWD1, SPG54" ENSG00000085788 "DDHD domain containing 2" O94830 8 38225218-38275558 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015202, HPA023143, HPA023147" Supported Supported "Centriolar satellite,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "Centriolar satellite" "CAB015202: , HPA023143: AB_1847534, HPA023147: AB_1847535" "unprognostic (1.49e-3)" "unprognostic (2.40e-1)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" "unprognostic (2.64e-1)" "prognostic favorable (7.72e-4)" "unprognostic (4.54e-2)" "unprognostic (1.79e-2)" "unprognostic (1.87e-1)" "unprognostic (2.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.49e-2)" "unprognostic (3.01e-3)" "unprognostic (3.21e-2)" "unprognostic (2.46e-1)" "unprognostic (7.88e-2)" "unprognostic (1.49e-1)" 28.9 18.1 27.3 14.4 32.1 14.9 19.4 33.8 39.7 22.0 23.5 20.1 19.6 20.9 23.3 20.9 19.1 17.5 27.7 30.1 29.3 21.6 12.1 16.9 19.8 32.1 27.7 28.9 22.2 21.1 18.3 15.2 35.1 22.6 16.7 31.7 18.3 29.3 32.0 16.8 22.2 18.2 30.7 17.2 15.0 22.7 32.4 19.5 18.7 35.8 22.3 17.6 17.7 38.8 57.7 26.1 58.3 28.3 21.8 30.6 18.4 18.1 33.0 42.5 38.4 30.8 22.6 22.8 24.1 32.8 26.3 22.7 33.9 34.1 64.9 19.8 22.6 83.0 36.0 29.9 19.6 9.6 12.8 16.0 26.4 26.4 26.8 27.0 51.5 31.2 59.6 24.5 27.3 12.3 66.6 14.7 13.2 9.5 15.1 34.0 50.1 16.5 22.5 34.8 21.2 32.0 44.4 21.9 22.2 18.2 26.3 26.1 46.6 24.8 31.1 24.3 28.4 25.7 25.8 54.0 39.5 18.4 35.3 2.5 3.9 4.7 10.6 4.9 11.8 9.8 9.6 11.9 6.5 15.2 10.2 7.5 0.3 16.5 3.5 3.8 15.6 7.3 27.3 32.1 33.8 39.7 30.1 29.3 32.1 27.7 35.1 30.7 32.4 38.8 15.4 22.4 7.0 20.5 17.3 13.8 10.6 8.2 14.2 27.9 12.7 7.4 23.9 8.6 8.4 20.2 18.8 12.1 16.2 7.2 23.5 11.6 4.5 9.7 13.4 13.8 15.7 25.2 51.3 11.0 11.5 13.6 12.8 12.4 21.0 22.8 12.5 5.5 7.4 53.8 51.2 9.3 6.1 8.4 11.2 10.8 20.2 7.7 19.6 21.5 13.0 19.9 16.5 35.7 46.9 16.2 6.2 20.7 24.0 10.2 23.8 10.0 5.4 5.9 6.6 17.6 13.6 30.9 35.3 8.7 10.7 6.4 17.9 13.4 8.9 7.7 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 264.5;Prostatic glandular cells: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.2;memory B-cell: 211.8;naive B-cell: 305.9" "Group enriched" "Detected in all" 7 "B-cells: 305.9;granulocytes: 80.2" "Cell line enhanced" "Detected in all" "RPMI-8226: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 12.6 18.6 12.5 21.5 13.0 16.6 24.4 15.8 16.1 29.4 36.5 30.2 41.6 16.1 81.7 13.9 28.3 27.9 8.6 12.6 14.4 27.6 33.0 16.0 28.1 12.7 13.5 18.6 114.5 13.7 52.4 14.0 12.4 74.5 35.5 8.5 85.7 30.5 4.8 10.7 40.3 11.4 11.5 28.0 46.1 7.8 13.5 10.2 29.2 3.0 32.3 21.2 14.1 13.0 15.1 29.7 17.4 35.7 33.2 32.1 23.9 42.1 52.7 21.0 27.3 13.8 22.7 1.0 35.1 43.8 30.5 16.5 14.5 30.9 18.2 9.6 9.3 26.6 13.1 40.5 56.3 7.8 30.8 25.3 31.5 29.4 38.3 37.2 34.7 34.9 1.3 67.2 25.9 31.2 17.7 13.0 26.5 61.2 10.0 19.1 12.8 140.0 53.3 19.4 13.6 20.8 17.3 26.5 25.4 15.4 56.9 15.0 21.2 14.8 13.1 25.2 11.3 41.5 29.4 4.5 41.0 20.5 26.1 80.2 12.9 23.4 13.4 13.7 23.0 211.8 17.8 17.7 12.2 305.9 8.8 8.5 8.0 22.4 19.7 26.0 18.0 17.0 12.5 13.0 15.8 16.1 12.6 14.4 12.7 13.5 12.4 11.5 13.5 13.0 22.2 9.6 46.2 0.0 110.8 0.0 81.8 0.0 25.6 5.9 49.4 42.3 0.0 32.9 21.7 75.4 16.7 45.1 14.8 12.4 43.0 68.0 30.6 70.3 27.3 27.9 44.9 9.9 0.0 89.9 43.5 41.5 50.4 54.8 31.5 38.1 17.5 23.4 36.5 62.2 0.0 62.6 0.0 10.1 0.0 8.9 17.7 23.0 0.0 0.0 12.0 37.4 18.6 0.0 0.0 57.2 31.1 9.4 264.5 146.3 74.3 24.9 55.4 3.6 13.1 22.8 18.9 31.4 12.3 20.8 0.0 88.1 25.2 18.5 44.1 59.1 NSD3 "FLJ20353, KMT3F, WHISTLE, WHSC1L1" ENSG00000147548 "Nuclear receptor binding SET domain protein 3" Q9BZ95 8 38269704-38382272 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 173.8;Syncytiotrophoblasts: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005659, CAB013721, HPA018893" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Mitochondria Nucleoplasm "CAB013721: , HPA005659: AB_1080596, HPA018893: AB_1858833" "unprognostic (6.21e-2)" "unprognostic (3.73e-2)" "unprognostic (2.18e-2)" "unprognostic (4.12e-1)" "unprognostic (2.25e-1)" "unprognostic (1.53e-2)" "unprognostic (4.35e-2)" "unprognostic (1.97e-2)" "unprognostic (2.49e-1)" "unprognostic (5.72e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (5.06e-2)" "unprognostic (5.60e-3)" "unprognostic (6.69e-2)" "unprognostic (4.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.60e-2)" 22.4 14.4 10.0 24.8 13.7 60.2 23.4 28.4 20.5 24.0 0.7 22.4 24.1 22.9 17.4 22.9 23.5 24.5 13.7 12.8 22.3 20.0 16.6 20.6 35.3 3.1 4.8 36.4 20.1 24.8 17.3 33.5 5.3 20.9 26.6 23.3 19.9 24.3 14.4 19.8 26.7 19.8 0.1 26.9 29.0 14.4 10.4 38.3 27.6 16.0 31.0 23.3 23.1 18.7 62.1 34.9 58.7 39.9 40.3 46.0 43.4 50.8 55.9 43.1 49.7 18.8 33.6 73.5 45.5 35.0 41.7 36.4 47.0 40.6 61.0 29.4 27.6 93.6 28.6 22.1 41.2 41.7 32.5 24.9 40.4 39.0 78.6 40.3 50.1 79.8 67.9 47.4 41.5 22.3 122.8 35.4 40.0 48.0 16.4 55.5 64.1 23.4 30.3 47.3 33.0 44.6 41.4 35.8 35.3 37.5 45.1 31.4 48.3 44.5 46.0 67.0 30.3 41.9 53.8 69.2 37.6 41.3 33.0 37.4 11.8 21.9 17.2 5.6 11.0 43.1 25.5 15.5 9.3 60.7 31.9 13.7 57.9 19.6 3.6 12.6 43.4 7.3 10.0 13.7 28.4 20.5 12.8 22.3 3.1 4.8 5.3 0.1 10.4 18.7 75.1 67.3 57.3 0.0 57.8 0.0 0.0 0.0 0.0 0.0 73.4 69.1 0.0 0.0 30.3 51.5 0.0 101.6 101.9 0.0 23.5 73.0 0.0 109.1 81.3 28.0 0.0 0.0 0.0 61.0 173.8 33.1 0.0 97.5 8.8 99.7 0.0 0.0 44.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 49.7 0.0 0.0 0.0 0.0 64.7 0.0 0.0 48.9 0.0 0.0 31.7 34.2 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 130.8 55.6 81.7 0.0 0.0 LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 76.9;Late spermatids: 57.6;Pancreatic endocrine cells: 48.6;Spermatocytes: 54.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.5" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.5" "Cell line enhanced" "Detected in many" "HBEC3-KT: 25.2;hTERT-HME1: 26.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 24.0" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: AB_1852808" "unprognostic (3.37e-2)" "unprognostic (2.73e-1)" "unprognostic (3.14e-1)" "unprognostic (2.05e-2)" "unprognostic (2.27e-4)" "unprognostic (3.20e-2)" "unprognostic (3.96e-2)" "unprognostic (1.43e-1)" "unprognostic (8.27e-2)" "unprognostic (3.80e-2)" "unprognostic (1.39e-1)" "unprognostic (1.35e-1)" "unprognostic (3.40e-2)" "unprognostic (4.09e-3)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (9.25e-2)" 1.2 1.0 3.4 1.1 3.6 5.3 0.7 5.7 4.9 1.6 2.9 0.7 0.8 1.4 1.1 1.1 1.4 1.2 0.8 3.2 2.8 2.3 0.7 2.0 1.3 2.3 2.9 2.1 0.7 1.6 1.3 1.8 3.1 1.1 0.8 4.2 0.4 0.8 0.2 1.1 0.5 0.6 2.0 1.6 2.7 23.8 2.6 2.4 1.0 0.3 1.4 1.9 0.6 4.2 21.2 4.5 3.0 2.9 2.3 7.0 2.5 7.5 9.2 10.6 6.2 1.5 8.3 2.8 16.5 1.5 3.1 2.2 5.9 25.2 11.7 1.2 2.9 3.2 2.3 4.2 2.7 0.7 2.8 1.7 7.2 11.7 26.9 5.9 10.7 3.4 2.6 3.9 9.3 4.2 7.5 1.8 0.8 1.6 18.2 2.9 4.8 1.6 16.8 1.1 2.4 2.3 2.5 0.4 0.9 1.8 2.4 1.2 20.0 3.3 22.5 7.4 1.7 2.6 1.6 2.0 5.6 3.3 2.5 1.3 4.1 0.7 0.9 1.6 2.0 1.5 0.9 1.5 1.7 1.8 1.7 1.7 21.5 1.4 5.0 0.7 5.2 1.3 3.4 3.6 5.7 4.9 3.2 2.8 2.3 2.9 3.1 2.0 2.6 4.2 3.0 3.2 6.4 2.3 10.3 0.5 13.9 7.6 6.8 6.6 2.1 3.3 1.8 4.3 3.2 5.5 6.2 2.6 10.1 1.4 1.9 4.0 76.9 21.8 7.1 4.2 0.0 0.8 3.6 20.5 7.9 5.0 16.8 20.5 9.5 1.1 1.4 0.0 1.4 6.7 7.3 1.9 2.0 2.2 2.3 57.6 2.1 3.6 1.8 1.0 2.0 3.6 1.0 1.5 1.6 48.6 0.1 1.5 4.5 2.9 0.3 3.0 4.9 8.4 0.0 4.5 3.3 54.8 3.3 2.5 0.9 8.1 9.1 1.5 1.3 4.5 FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Kallmann syndrome, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 176.7;Leydig cells: 192.0;Oligodendrocyte precursor cells: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AN3-CA: 508.7;BJ hTERT+: 278.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033614, HPA056402" Approved NA NA 78000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "CAB033614: AB_783377, HPA056402: AB_2683118" "unprognostic (9.53e-2)" "unprognostic (7.33e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.23e-3)" "unprognostic (7.02e-2)" "unprognostic (6.59e-2)" "unprognostic (2.77e-1)" "unprognostic (1.81e-1)" "unprognostic (3.99e-2)" "unprognostic (7.97e-3)" "unprognostic (4.59e-2)" "unprognostic (7.69e-2)" "unprognostic (6.87e-3)" "unprognostic (5.60e-2)" "unprognostic (4.59e-3)" "unprognostic (1.05e-3)" 95.1 12.8 27.5 15.9 24.6 14.1 87.1 48.8 22.4 79.8 37.2 97.2 8.8 74.2 15.8 35.8 85.9 57.1 89.9 30.9 28.8 40.1 9.1 55.7 16.6 35.9 37.3 108.2 98.6 20.4 57.1 51.3 63.7 60.5 17.9 15.8 31.4 53.6 24.8 35.6 41.7 57.1 30.3 9.9 40.4 20.4 33.4 17.1 33.7 23.3 16.1 79.3 63.9 29.6 12.9 42.0 198.0 508.7 120.1 91.2 142.9 136.7 278.8 90.0 95.8 27.3 6.5 1.8 38.3 127.7 103.9 0.2 90.0 6.8 104.3 39.2 24.1 0.0 7.7 27.8 69.7 31.1 0.6 80.5 0.7 70.9 13.3 45.6 86.9 6.0 11.9 0.4 40.5 12.5 91.5 9.2 145.9 1.6 21.6 86.3 21.1 0.4 35.6 0.3 7.9 19.4 23.4 1.0 5.1 93.4 9.3 5.4 51.4 49.2 28.9 149.6 29.7 2.4 4.1 0.5 60.3 1.7 27.1 0.2 0.3 0.1 1.7 0.1 1.1 0.3 0.7 1.2 0.0 0.6 0.5 1.5 0.6 0.4 0.2 0.2 1.0 0.1 27.5 24.6 48.8 22.4 30.9 28.8 35.9 37.3 63.7 30.3 33.4 29.6 101.0 3.2 15.8 55.8 1.8 31.5 95.9 1.1 37.0 4.4 28.7 77.7 52.5 24.3 5.1 9.2 4.2 8.3 6.3 0.4 0.0 27.3 15.3 48.2 40.6 75.5 25.0 3.6 25.4 65.2 80.5 176.7 3.1 75.3 8.2 40.4 47.5 0.8 25.3 21.9 21.1 0.6 4.1 5.6 75.2 15.0 192.0 11.7 33.8 19.7 1.7 88.1 6.2 166.4 14.2 21.6 0.3 99.6 6.4 94.7 0.1 7.9 1.0 3.3 13.1 118.9 59.9 1.6 14.1 4.8 19.7 10.4 14.1 2.1 0.7 11.7 TACC1 ENSG00000147526 "Transforming acidic coiled-coil containing protein 1" O75410 8 38728186-38853028 "Predicted intracellular proteins" "Cell cycle, Cell division" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 554.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.8;granulocytes: 31.5;monocytes: 14.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017041, HPA024702, HPA056841" Approved Approved Cytosol NA NA 47000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "CAB017041: , HPA024702: AB_1857723, HPA056841: " "unprognostic (1.83e-2)" "unprognostic (3.07e-1)" "unprognostic (2.18e-1)" "unprognostic (8.31e-2)" "unprognostic (6.55e-2)" "unprognostic (5.30e-2)" "unprognostic (1.79e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (7.85e-2)" "unprognostic (1.63e-1)" "unprognostic (5.94e-2)" "prognostic favorable (1.06e-5)" "unprognostic (1.03e-3)" "unprognostic (2.84e-2)" "unprognostic (2.15e-2)" "unprognostic (1.18e-1)" 151.8 31.5 32.8 39.5 41.0 68.4 67.7 23.2 36.3 73.8 19.0 76.8 21.5 84.0 14.1 70.5 64.0 47.5 42.4 27.0 25.9 51.6 23.8 67.7 41.9 28.6 34.9 35.9 44.5 29.6 14.1 74.4 27.6 54.8 44.0 15.9 19.1 75.5 20.3 19.4 40.3 90.9 25.6 61.2 38.7 29.2 37.2 27.1 34.4 56.4 34.9 58.6 36.8 49.3 39.4 74.2 53.2 16.6 55.9 38.9 34.8 50.1 64.4 46.8 47.6 34.6 5.9 40.1 29.9 49.5 40.5 36.7 32.0 22.7 96.5 28.8 12.1 155.5 22.8 22.4 65.8 31.4 69.0 71.2 20.6 76.2 24.1 48.5 169.8 47.5 16.4 97.9 143.0 29.2 74.4 17.9 7.6 63.5 35.0 16.7 120.3 7.1 15.9 38.2 3.8 4.2 40.6 41.5 33.9 31.6 19.3 23.9 138.0 56.5 34.3 72.8 40.9 50.5 35.5 35.2 51.4 35.7 69.8 13.7 11.7 15.7 6.0 10.5 6.5 2.0 4.0 5.0 7.6 2.3 3.2 3.6 31.5 3.8 14.3 34.8 3.4 5.8 32.8 41.0 23.2 36.3 27.0 25.9 28.6 34.9 27.6 25.6 37.2 49.3 554.0 218.0 152.9 67.9 66.7 35.2 55.5 9.3 148.0 35.2 14.3 25.1 53.9 191.6 32.7 46.0 62.6 66.2 122.9 30.0 119.3 176.4 4.3 34.9 51.2 251.0 37.8 79.3 109.1 60.2 64.3 147.5 25.0 79.0 115.8 42.1 350.5 39.2 79.0 109.4 73.8 121.2 6.1 90.9 158.7 11.5 168.4 128.8 40.9 203.3 87.1 59.8 51.5 44.2 134.3 47.5 44.2 206.1 73.7 62.4 3.4 23.5 7.7 44.2 190.7 150.0 223.3 42.9 62.3 45.5 18.9 94.0 81.5 43.4 48.7 40.0 PLEKHA2 TAPP2 ENSG00000169499 "Pleckstrin homology domain containing A2" 8 38901235-38973912 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 78.7" "Cell type enhanced" "Detected in many" "B-cells: 94.1;dendritic cells: 132.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 164.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004706 Approved Uncertain "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA004706: AB_1079633" "unprognostic (2.78e-1)" "unprognostic (8.80e-3)" "unprognostic (4.15e-3)" "unprognostic (3.03e-1)" "unprognostic (8.61e-2)" "unprognostic (9.07e-3)" "unprognostic (6.16e-3)" "unprognostic (1.45e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.39e-2)" "unprognostic (6.59e-2)" "prognostic unfavorable (1.95e-6)" "unprognostic (2.39e-2)" "unprognostic (1.00e-1)" "unprognostic (4.55e-2)" "unprognostic (9.60e-3)" 17.5 15.7 13.6 35.3 11.1 39.7 10.6 6.1 18.3 16.9 13.1 16.9 10.1 15.0 10.6 14.0 15.8 17.7 42.8 25.3 10.2 17.1 9.4 20.1 78.7 10.7 6.9 19.1 6.6 21.2 8.7 17.8 11.8 10.2 12.4 5.4 7.4 18.8 4.5 8.4 16.0 18.9 10.1 43.0 12.6 5.9 10.1 17.9 19.3 8.0 66.1 17.3 10.3 16.3 30.0 6.5 4.1 10.0 10.2 20.1 4.6 35.7 27.2 25.9 21.5 3.7 19.4 164.7 41.3 31.9 22.9 17.9 10.8 21.6 38.4 42.8 1.0 84.7 54.4 4.0 36.9 28.0 32.9 46.3 14.7 13.2 23.6 60.1 4.4 26.3 8.7 45.0 24.1 3.7 56.0 12.8 3.9 23.2 10.2 14.1 22.4 34.6 31.3 24.9 0.5 6.5 41.9 7.4 27.9 6.1 16.9 13.0 6.5 18.5 14.5 3.2 28.5 14.7 14.8 76.3 29.3 28.7 4.2 6.9 1.5 8.1 1.9 2.0 2.0 10.0 2.2 2.3 1.8 12.7 1.4 2.6 3.3 3.9 2.2 5.4 1.9 1.0 13.6 11.1 6.1 18.3 25.3 10.2 10.7 6.9 11.8 10.1 10.1 16.3 8.8 3.2 17.9 15.0 94.1 8.8 15.7 17.1 6.8 1.8 7.2 5.2 40.7 12.8 17.3 40.5 0.0 7.7 132.0 9.0 1.9 7.4 1.0 17.8 28.7 10.9 13.1 12.2 21.2 5.5 17.7 22.2 9.2 25.4 36.8 21.3 19.6 10.2 48.8 58.9 7.7 11.8 6.1 79.6 55.3 2.5 22.7 49.7 16.0 35.6 48.4 12.1 64.9 52.3 4.7 24.5 4.7 25.2 56.4 9.9 15.9 16.3 23.5 1.4 13.1 35.8 24.8 0.7 7.9 5.1 6.7 4.5 53.9 4.4 12.8 35.7 HTRA4 FLJ90724 ENSG00000169495 "HtrA serine peptidase 4" P83105 8 38974228-38988663 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 67.0" "Cell type enriched" "Detected in some" 10 "Extravillous trophoblasts: 444.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "BEWO: 233.6" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in all" HPA045402 Enhanced "Secreted in female reproductive system" NA NA 23000 "Cluster 17: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "HPA045402: AB_2679316" "unprognostic (1.20e-1)" "unprognostic (5.83e-4)" "unprognostic (8.02e-2)" "unprognostic (2.13e-2)" "unprognostic (8.20e-2)" "unprognostic (2.42e-2)" "unprognostic (1.80e-1)" "unprognostic (7.40e-3)" "unprognostic (1.40e-1)" "unprognostic (5.14e-4)" "unprognostic (1.01e-1)" "unprognostic (8.68e-2)" "unprognostic (1.42e-1)" "unprognostic (4.58e-1)" "unprognostic (5.19e-3)" "unprognostic (2.39e-3)" "unprognostic (1.19e-3)" 0.8 0.5 0.8 0.8 1.2 7.2 1.2 3.5 5.0 0.9 0.0 0.5 0.3 0.9 0.9 0.1 0.3 0.5 0.3 1.3 0.9 0.4 0.5 2.0 2.5 0.6 0.5 0.6 0.8 0.5 0.1 67.0 0.6 0.6 0.7 1.8 0.3 1.1 1.0 0.8 0.4 0.7 0.1 1.2 0.4 0.9 1.4 0.5 0.5 0.1 1.7 0.4 0.1 2.0 0.4 0.3 0.2 0.4 0.8 0.4 233.6 0.6 0.4 0.3 0.4 0.4 0.5 0.5 0.2 0.2 0.4 0.4 0.2 0.2 0.1 0.2 0.4 0.4 0.7 0.3 0.2 0.6 0.6 0.7 0.2 0.2 0.5 0.3 0.2 0.2 0.4 1.3 0.2 0.5 0.4 0.3 0.3 0.1 0.2 0.2 0.2 0.4 0.2 0.7 0.4 0.6 0.5 0.3 0.1 9.6 0.5 0.7 0.0 0.7 0.5 0.3 0.3 0.5 0.2 0.2 0.2 0.7 0.2 0.3 0.1 0.4 0.2 0.1 0.3 0.2 0.2 0.2 0.1 0.5 0.2 0.2 0.5 0.2 0.2 0.5 0.3 0.0 0.8 1.2 3.5 5.0 1.3 0.9 0.6 0.5 0.6 0.1 1.4 2.0 0.1 0.0 0.0 0.0 1.0 0.1 1.7 0.1 1.2 0.5 0.1 0.3 0.7 0.0 0.0 0.0 2.1 2.8 1.1 0.1 0.0 0.0 0.1 0.2 0.7 0.3 0.0 0.0 0.4 0.0 444.0 1.2 0.0 0.5 0.0 0.7 1.4 0.0 11.6 1.7 0.2 0.0 0.0 0.6 0.3 0.0 0.0 3.8 1.8 1.0 0.0 0.4 1.0 1.5 0.2 0.3 0.0 0.0 0.5 1.5 0.0 0.2 0.1 0.2 0.0 3.5 0.2 0.0 0.1 0.0 0.1 40.4 0.7 0.2 0.2 1.1 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 189.0;Excitatory neurons: 37.3;Late spermatids: 50.5;Spermatocytes: 99.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.0;MCF7: 1.1;U-2 OS: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA044156, HPA062151" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA044156: AB_10796798, HPA062151: AB_2684699" "unprognostic (2.13e-1)" "unprognostic (6.92e-2)" "unprognostic (4.63e-3)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.52e-2)" "unprognostic (5.66e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-1)" "unprognostic (3.38e-2)" "unprognostic (1.13e-7)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (8.34e-3)" "unprognostic (7.82e-2)" 1.0 1.0 1.0 0.2 0.9 0.4 1.0 3.2 1.5 0.6 0.0 0.5 0.0 0.4 0.6 0.2 0.5 0.4 0.7 0.9 1.3 0.2 0.0 0.3 0.1 0.1 0.5 0.6 1.8 0.0 0.4 0.1 0.4 0.6 0.4 0.9 0.5 0.3 0.2 0.7 0.2 0.1 0.1 0.7 0.3 27.4 1.0 0.0 0.3 0.1 0.1 0.5 0.4 1.3 0.2 0.4 0.0 0.2 0.6 0.0 0.0 0.4 0.1 0.4 0.2 0.1 0.9 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.2 0.5 1.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 1.0 0.9 3.2 1.5 0.9 1.3 0.1 0.5 0.4 0.1 1.0 1.3 1.0 0.0 0.0 11.8 0.0 0.9 1.1 0.7 0.6 8.2 2.5 2.3 1.7 1.5 0.4 1.8 18.8 0.3 0.1 0.4 0.0 0.4 189.0 5.7 3.6 1.0 4.2 0.0 37.3 1.3 0.2 2.4 0.0 9.8 0.0 3.3 0.7 0.4 0.5 0.0 29.8 1.1 0.0 0.0 1.0 50.5 2.8 0.6 0.0 9.4 0.1 1.0 0.0 18.6 17.6 2.8 0.1 3.0 0.1 1.7 0.0 0.2 1.4 3.8 0.0 3.4 0.9 99.9 2.9 0.5 0.0 0.1 0.2 3.7 1.4 1.5 ADAM18 "ADAM27, tMDCIII" ENSG00000168619 "ADAM metallopeptidase domain 18" Q9Y3Q7 8 39584489-39730065 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 74 "testis: 9.2" "Cell type enhanced" "Detected in some" "Early spermatids: 63.5;Late spermatids: 26.8;Spermatocytes: 141.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (2.10e-4)" "unprognostic (1.18e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 63.5 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 26.8 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 141.1 3.1 0.0 0.0 2.5 0.0 0.0 0.0 0.0 ADAM2 "CT15, FTNB, PH-30b, PH30" ENSG00000104755 "ADAM metallopeptidase domain 2" Q99965 8 39743735-39838289 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 129 "testis: 38.1" "Group enriched" "Detected in some" 4 "Early spermatids: 28.2;Spermatocytes: 96.8" "Cancer enriched" "Detected in single" 5 "prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB022390, HPA024621, HPA026581" Enhanced NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "CAB022390: , HPA024621: AB_1844576, HPA026581: AB_1844577" "unprognostic (4.74e-2)" "unprognostic (1.67e-3)" "unprognostic (3.82e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 96.8 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016391 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "liver: 5.4;placenta: 4.0" "Cell type enhanced" "Detected in some" "Early spermatids: 21.0;Endometrial ciliated cells: 18.4;Glandular and luminal cells: 51.3;Late spermatids: 6.9;monocytes: 14.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054911 Approved Cytosol NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 44: Endometrium - Transcription" Cytosol "HPA054911: " "unprognostic (2.00e-3)" "unprognostic (2.34e-5)" "unprognostic (2.22e-3)" "unprognostic (4.41e-3)" "unprognostic (5.37e-2)" "unprognostic (3.69e-5)" "unprognostic (1.19e-1)" "unprognostic (4.73e-3)" "unprognostic (1.20e-2)" "unprognostic (2.78e-1)" "unprognostic (4.11e-3)" "unprognostic (2.25e-1)" "unprognostic (6.47e-7)" "unprognostic (3.25e-2)" "unprognostic (1.96e-3)" "unprognostic (3.35e-2)" "unprognostic (3.08e-3)" 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.1 21.0 18.4 4.4 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 51.3 0.0 0.0 0.0 2.6 0.2 0.0 0.4 0.0 0.0 0.0 1.9 6.9 0.3 0.8 0.0 0.0 14.6 0.0 0.0 0.5 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.1 0.4 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.1 TCIM "C8orf4, hTC-1, TC-1, TC1" ENSG00000176907 "Transcriptional and immune response regulator" Q9NR00 8 40153482-40155310 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 209.5;Alveolar cells type 2: 882.5;Collecting duct cells: 200.5;Distal tubular cells: 193.7;Ductal cells: 331.6;Glandular and luminal cells: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 48.5;AF22: 134.4;BJ: 51.5;BJ hTERT+: 134.4;EFO-21: 87.5;HeLa: 94.8;RPTEC TERT1: 67.2;SuSa: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027188 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Plasma membrane, Cytosol" "HPA027188: AB_10601150" "unprognostic (8.88e-2)" "unprognostic (2.76e-2)" "unprognostic (7.89e-3)" "unprognostic (7.95e-2)" "unprognostic (7.33e-3)" "unprognostic (1.87e-3)" "unprognostic (2.11e-1)" "unprognostic (2.32e-1)" "unprognostic (2.93e-2)" "unprognostic (8.15e-2)" "unprognostic (6.23e-2)" "unprognostic (8.19e-2)" "unprognostic (2.54e-2)" "unprognostic (5.32e-3)" "unprognostic (1.39e-1)" "unprognostic (9.13e-3)" "unprognostic (4.48e-2)" 91.5 24.2 6.2 42.9 7.4 0.0 64.0 6.0 10.8 134.1 10.6 68.7 30.9 67.7 18.3 22.3 20.3 105.2 130.8 6.5 6.5 252.6 210.0 165.4 18.0 6.5 6.6 44.6 51.5 70.3 18.9 165.1 6.9 67.7 71.1 4.5 176.0 28.3 37.7 13.2 101.4 43.5 6.9 83.3 56.1 4.8 8.6 3.8 53.9 47.9 4.1 255.3 26.2 7.8 0.0 48.5 134.4 0.0 0.0 0.0 0.3 51.5 134.4 0.2 0.6 0.7 0.0 0.0 87.5 1.0 0.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 94.8 21.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.2 67.2 0.1 0.1 0.2 0.2 4.6 0.0 50.4 0.0 0.0 43.6 0.0 1.2 0.4 0.8 1.2 1.7 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 7.4 6.0 10.8 6.5 6.5 6.5 6.6 6.9 6.9 8.6 7.8 209.5 99.3 882.5 0.0 2.8 0.0 0.0 0.0 0.0 0.0 124.9 62.0 0.0 0.0 77.4 200.5 0.0 12.3 1.5 0.0 193.7 331.6 0.0 152.6 90.7 103.2 0.0 0.0 0.0 111.2 26.5 13.5 0.0 397.4 26.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 102.4 0.0 0.0 0.1 0.0 0.0 2.5 8.7 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 4.5 8.1 22.7 0.0 0.0 ZMAT4 FLJ13842 ENSG00000165061 "Zinc finger matrin-type 4" Q9H898 8 40530590-40897833 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 15.5;retina: 4.4;thyroid gland: 16.3" "Group enriched" "Detected in some" 6 "Excitatory neurons: 220.9;Inhibitory neurons: 507.5" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 86 "NK-cell: 8.6" "Lineage enriched" "Detected in single" 86 "NK-cells: 8.6" "Group enriched" "Detected in some" 5 "AF22: 22.5;U-2197: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069813, HPA071585" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 48: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "HPA069813: AB_2686206, HPA071585: AB_2686423" "unprognostic (1.25e-2)" "unprognostic (9.29e-2)" "unprognostic (2.80e-1)" "unprognostic (2.83e-3)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (1.07e-1)" "unprognostic (9.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-2)" "unprognostic (4.46e-4)" "unprognostic (5.44e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (4.79e-3)" 0.0 0.7 3.2 0.1 7.5 0.0 0.1 1.6 15.0 1.4 0.0 0.7 0.0 0.3 0.1 0.0 0.1 0.1 0.4 6.2 2.7 0.3 0.0 0.0 0.1 15.5 4.5 0.4 0.1 0.0 1.8 0.1 15.4 0.6 0.2 4.4 0.0 0.4 0.0 0.1 0.0 0.0 0.3 0.3 0.1 1.4 11.1 0.3 16.3 0.0 0.1 0.0 0.0 4.1 0.0 1.3 22.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.3 0.0 0.0 0.3 0.0 0.0 1.1 0.3 0.0 0.0 0.0 1.7 3.6 0.0 0.0 0.0 0.6 14.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.1 3.2 7.5 1.6 15.0 6.2 2.7 15.5 4.5 15.4 0.3 11.1 4.1 0.0 0.0 0.0 2.0 0.0 0.0 0.4 0.0 0.0 8.5 0.1 0.0 0.9 2.8 0.0 0.0 6.2 0.0 1.0 0.0 1.9 0.0 19.7 0.0 0.1 0.0 1.8 0.0 220.9 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 507.5 0.0 0.0 0.0 0.0 55.2 2.8 0.0 0.0 7.5 0.0 1.3 42.2 13.0 4.0 0.0 0.0 2.2 0.0 0.1 0.0 0.1 0.0 1.8 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.1 0.3 0.6 0.1 0.1 SFRP1 "FRP, FRP-1, SARP2" ENSG00000104332 "Secreted frizzled related protein 1" Q8N474 8 41261962-41309473 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 299.3;choroid plexus: 509.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 710.9;Breast myoepithelial cells: 1158.6;Cardiomyocytes: 266.3;Leydig cells: 578.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 3203.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008116, HPA064870" Approved Approved Nucleoli,Cytosol "Secreted in other tissues" Yes No 1300000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 35: Glandular cells - Unknown function" Nucleoli Cytosol "CAB008116: AB_2187070, HPA064870: AB_2685376" "unprognostic (1.23e-3)" "unprognostic (7.01e-2)" "unprognostic (2.14e-1)" "unprognostic (3.59e-1)" "unprognostic (7.13e-2)" "prognostic favorable (1.55e-4)" "unprognostic (1.79e-1)" "unprognostic (2.69e-3)" "unprognostic (2.15e-2)" "unprognostic (4.67e-3)" "unprognostic (3.52e-3)" "unprognostic (4.74e-2)" "unprognostic (1.72e-2)" "unprognostic (1.75e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (3.12e-4)" 88.4 12.9 9.2 10.5 12.7 1.4 299.3 18.2 15.0 203.7 509.2 24.5 12.2 132.5 1.8 26.1 98.5 61.3 124.8 29.4 8.5 115.3 6.1 4.7 4.0 29.9 10.5 46.8 6.2 1.4 1.2 19.5 29.7 42.6 30.1 2.2 236.9 102.3 2.6 55.4 18.9 82.9 7.7 21.4 24.4 28.4 10.8 3.1 12.7 32.8 3.2 44.9 95.6 24.7 0.1 29.0 75.9 1.9 67.5 3.9 14.5 132.9 694.5 197.9 187.2 0.0 17.8 0.0 0.6 0.7 15.8 0.9 10.8 53.7 277.6 0.0 2.3 0.0 0.0 0.0 6.4 0.0 0.7 11.8 255.9 19.9 19.3 3203.5 6.2 0.2 0.0 0.0 3.7 0.0 0.0 0.2 205.8 0.1 0.3 0.0 15.7 0.0 422.6 0.0 4.1 18.5 5.5 0.0 41.5 264.7 0.1 2.1 1.9 0.1 19.6 0.2 18.3 0.0 0.0 0.0 0.2 0.0 279.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 12.7 18.2 15.0 29.4 8.5 29.9 10.5 29.7 7.7 10.8 24.7 8.4 0.0 0.0 2.0 1.2 11.2 134.0 1.4 147.4 1.8 710.9 1158.6 266.3 0.0 0.7 62.5 2.1 2.2 9.1 0.0 80.3 4.4 5.0 3.0 131.6 21.0 0.0 0.0 0.2 0.0 82.0 229.5 16.8 3.4 0.0 19.3 53.6 0.3 2.0 1.7 12.1 0.0 0.0 0.3 4.0 25.7 578.4 4.0 99.6 0.0 0.0 76.2 0.0 7.5 20.6 0.1 0.0 130.1 2.1 29.7 0.0 3.2 0.0 1.8 0.0 34.9 18.0 2.3 16.8 53.7 5.5 0.8 7.3 72.6 0.0 9.3 GOLGA7 "GCP16, GOLGA3AP1, GOLGA7A, HSPC041" ENSG00000147533 "Golgin A7" Q7Z5G4 8 41490396-41510980 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046878 Uncertain NA NA "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" "HPA046878: AB_2679854" "unprognostic (2.93e-1)" "unprognostic (9.56e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.36e-4)" "unprognostic (1.22e-1)" "unprognostic (3.01e-2)" "unprognostic (6.74e-2)" "unprognostic (1.91e-1)" "unprognostic (2.80e-1)" "unprognostic (4.36e-2)" "unprognostic (1.31e-1)" "unprognostic (1.68e-1)" "unprognostic (1.85e-1)" "unprognostic (2.56e-2)" "unprognostic (1.12e-1)" "unprognostic (2.81e-1)" "unprognostic (1.88e-1)" 41.3 31.5 73.8 28.7 91.2 42.6 34.1 78.5 112.3 30.5 56.6 29.9 31.6 33.6 27.9 34.5 23.2 33.3 28.1 73.6 78.2 42.8 46.9 30.3 36.9 84.1 83.6 31.2 32.4 33.7 15.8 48.6 82.3 30.6 26.0 31.7 38.8 26.5 25.5 47.8 32.1 32.0 75.4 36.3 28.5 40.8 76.6 36.5 28.5 29.8 32.0 33.1 24.8 110.0 58.2 64.9 48.2 56.1 59.8 51.7 36.8 49.6 48.5 57.2 63.0 115.8 53.3 27.9 64.4 46.7 54.6 39.6 48.0 38.6 63.5 39.3 42.7 56.5 36.7 48.0 65.3 26.2 45.3 45.6 71.1 36.6 54.1 46.3 56.5 49.4 68.1 53.9 46.7 42.6 83.6 70.7 54.1 53.1 31.2 50.4 86.8 30.6 66.9 53.3 86.1 55.5 44.6 34.4 90.7 40.3 70.5 49.9 58.9 48.2 46.4 61.7 44.0 40.7 67.7 40.7 51.3 44.5 68.3 204.9 78.1 78.8 83.9 68.5 82.2 34.8 79.4 76.9 59.2 32.9 65.8 65.9 136.7 78.0 68.1 40.5 94.9 139.7 73.8 91.2 78.5 112.3 73.6 78.2 84.1 83.6 82.3 75.4 76.6 110.0 74.6 6.4 22.9 11.8 31.4 110.4 53.9 63.1 44.3 28.3 48.3 42.9 25.5 28.6 38.4 29.5 4.2 61.2 69.6 29.5 95.9 62.7 22.2 28.1 43.1 57.4 42.5 33.9 15.8 48.0 68.4 55.0 29.6 36.5 17.7 35.4 52.5 46.6 64.3 18.5 17.8 30.3 59.0 69.7 95.2 21.7 45.1 53.7 60.5 13.1 65.5 77.9 87.6 14.6 90.5 55.1 21.0 62.1 31.2 77.0 53.2 120.5 28.4 30.7 59.2 49.2 60.4 152.3 135.0 43.5 108.5 85.9 69.5 38.1 30.5 55.4 GINS4 "MGC14799, SLD5" ENSG00000147536 "GINS complex subunit 4" Q9BRT9 8 41529218-41545030 "Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.2" "Cell type enhanced" "Detected in many" "Granulosa cells: 17.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024663, HPA026580" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Centrosome "HPA024663: AB_1857224, HPA026580: AB_1857225" "unprognostic (7.74e-2)" "unprognostic (3.72e-2)" "unprognostic (2.25e-3)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.70e-1)" "unprognostic (4.01e-2)" "unprognostic (1.71e-3)" "unprognostic (8.01e-3)" "unprognostic (4.03e-3)" "unprognostic (1.50e-2)" "unprognostic (4.34e-4)" "unprognostic (1.79e-1)" "unprognostic (3.67e-5)" "unprognostic (2.40e-3)" "unprognostic (1.39e-1)" "unprognostic (4.11e-1)" "unprognostic (3.22e-1)" 0.8 0.8 0.9 4.0 1.2 5.9 1.8 1.5 1.1 0.9 0.9 2.1 1.6 1.4 0.7 1.7 0.8 1.5 0.7 0.9 0.9 0.6 1.4 0.7 5.1 1.4 1.0 1.1 0.9 0.6 0.2 2.6 1.2 0.7 3.0 0.8 0.8 0.5 0.5 2.1 1.7 1.5 0.5 1.7 1.3 2.9 1.0 6.2 1.3 0.1 6.0 1.2 0.8 2.3 20.3 28.3 39.4 17.9 2.4 3.1 16.4 28.1 16.9 28.8 33.6 26.4 17.3 28.1 11.2 14.3 21.6 15.0 32.1 23.4 41.9 10.4 17.8 40.8 20.6 17.9 0.6 8.9 20.2 1.7 1.1 47.2 10.4 6.6 14.4 33.0 20.3 9.0 20.4 13.8 37.6 10.1 22.0 21.5 15.4 34.4 36.8 11.8 10.3 19.1 12.2 9.5 20.3 8.8 8.1 19.9 22.8 9.9 10.0 19.3 28.9 36.1 28.8 10.6 16.4 33.0 13.8 20.9 48.3 1.5 0.7 0.3 1.5 0.7 0.9 1.2 2.5 1.0 0.3 2.8 1.5 1.0 1.9 1.4 0.3 2.9 3.7 1.0 0.9 1.2 1.5 1.1 0.9 0.9 1.4 1.0 1.2 0.5 1.0 2.3 1.3 0.0 1.1 0.7 6.4 2.8 2.8 2.3 1.2 4.0 2.1 4.3 0.8 0.0 1.3 9.2 2.1 9.1 5.6 3.7 0.0 1.8 0.9 2.0 2.3 1.9 3.5 9.9 0.2 1.8 12.4 3.5 4.1 3.7 1.3 17.5 1.1 0.5 4.8 0.0 0.7 4.0 4.1 1.8 9.4 0.6 1.2 5.7 0.0 0.0 9.6 1.7 3.1 0.0 2.5 2.1 0.3 2.2 9.2 1.2 0.5 0.9 0.3 2.5 0.0 3.6 5.9 9.6 11.8 2.5 1.1 5.9 6.9 9.0 6.0 1.6 GPAT4 "AGPAT6, DKFZp586M1819, LPAAT-zeta, TSARG7" ENSG00000158669 "Glycerol-3-phosphate acyltransferase 4" Q86UL3 8 41577187-41625001 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016471 Approved NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "HPA016471: AB_1844649" "unprognostic (3.05e-2)" "unprognostic (4.05e-2)" "unprognostic (4.24e-2)" "prognostic unfavorable (9.37e-4)" "unprognostic (7.45e-2)" "unprognostic (2.99e-3)" "unprognostic (5.08e-2)" "unprognostic (5.11e-2)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.98e-2)" "prognostic favorable (4.15e-4)" "unprognostic (1.73e-3)" "unprognostic (3.16e-2)" "unprognostic (3.35e-1)" "unprognostic (2.04e-2)" "prognostic favorable (5.65e-4)" 23.6 33.6 13.5 28.0 15.3 28.4 42.4 29.7 17.6 24.7 25.0 21.3 19.7 28.6 12.8 16.3 21.0 23.1 20.4 13.4 15.0 30.1 32.7 23.9 22.3 16.2 16.5 23.0 23.1 40.5 16.2 27.2 15.6 18.3 21.7 15.4 25.4 20.3 57.6 18.4 19.0 33.2 15.4 21.2 26.8 24.2 15.7 22.1 20.0 39.9 27.4 24.6 18.8 16.8 39.0 42.4 49.7 38.9 53.1 64.1 43.7 82.7 70.8 61.4 63.6 28.7 76.1 53.8 56.6 68.7 75.4 22.0 58.7 37.3 78.8 58.0 32.4 63.0 49.0 26.5 31.0 6.8 87.1 40.6 26.9 64.0 23.0 52.5 64.1 52.7 47.9 61.5 63.4 16.5 60.0 17.3 53.1 71.3 22.5 34.7 49.8 29.2 36.4 57.5 32.4 44.7 32.2 43.9 89.1 56.5 60.9 42.4 47.0 63.0 43.8 73.0 62.6 33.0 47.9 58.7 51.9 36.9 63.1 16.0 17.0 7.8 12.5 15.9 11.6 8.6 9.6 12.6 21.0 9.9 8.5 8.5 3.8 5.8 14.3 8.0 9.7 13.8 13.5 15.3 29.7 17.6 13.4 15.0 16.2 16.5 15.6 15.4 15.7 16.8 20.0 3.2 31.2 0.0 14.5 0.0 13.2 0.0 11.4 16.9 50.2 19.6 0.0 27.1 13.6 11.0 10.4 33.9 18.4 10.8 3.9 41.3 40.6 14.1 19.4 21.7 17.0 21.5 0.0 39.8 42.5 13.1 27.0 29.2 2.5 21.2 18.2 62.4 27.1 15.2 0.0 14.2 0.0 28.1 0.0 58.7 12.8 31.7 0.0 0.0 31.2 11.8 9.2 0.0 0.0 44.9 11.3 10.5 23.9 27.7 13.3 28.2 5.8 15.1 6.6 20.3 11.6 4.3 14.8 10.1 0.0 40.4 16.7 23.0 11.1 18.2 NKX6-3 FLJ25169 ENSG00000165066 "NK6 homeobox 3" A6NJ46 8 41645177-41650817 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 28.0" "Cell type enriched" "Detected in single" 5 "Gastric mucus-secreting cells: 2.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 3.1;stomach cancer: 3.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Daudi: 4.9;THP-1: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 4: Stomach - Digestion" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "unprognostic (1.87e-1)" "unprognostic (9.91e-3)" "unprognostic (4.04e-1)" "unprognostic (5.73e-2)" "unprognostic (1.98e-1)" "unprognostic (1.65e-1)" "unprognostic (6.36e-2)" "unprognostic (1.13e-1)" "unprognostic (2.17e-2)" "unprognostic (1.92e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.3 0.1 0.5 0.1 0.0 2.5 1.0 0.0 0.3 0.1 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 1.5 0.5 0.9 0.0 0.9 1.8 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.3 28.0 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 2.5 1.0 0.4 0.4 0.5 0.9 0.6 0.4 0.4 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANK1 "ANK, SPH1" ENSG00000029534 "Ankyrin 1" P16157 8 41653220-41896762 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Elliptocytosis, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 993.4;tongue: 629.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 164.7;Cone photoreceptor cells: 87.6;Erythroid cells: 250.2;Inhibitory neurons: 176.8;Skeletal myocytes: 51.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory B-cell: 9.2;naive B-cell: 7.8;plasmacytoid DC: 3.4" "Group enriched" "Detected in many" 4 "B-cells: 9.2;dendritic cells: 3.4" "Group enriched" "Detected in many" 4 "HEL: 125.2;K-562: 134.3;RH-30: 160.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004842, HPA056953" Supported Supported "Intracellular and membrane" NA NA 4200000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA004842: AB_1844827, HPA056953: AB_2683284" "unprognostic (1.05e-1)" "unprognostic (1.30e-1)" "unprognostic (4.22e-3)" "unprognostic (2.31e-3)" "unprognostic (1.76e-7)" "unprognostic (2.03e-1)" "unprognostic (2.15e-1)" "unprognostic (2.52e-1)" "unprognostic (2.95e-1)" "unprognostic (3.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (3.86e-1)" "unprognostic (4.65e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" 1.8 1.1 0.4 1.6 2.0 95.2 1.0 34.1 17.3 0.3 0.0 0.5 1.5 0.1 0.1 8.7 0.4 0.8 98.0 0.3 12.5 0.6 0.3 0.7 4.4 26.8 32.6 0.3 0.8 62.1 1.1 2.1 27.1 4.2 0.2 6.3 8.1 0.7 993.4 0.6 0.9 0.3 10.6 2.2 4.4 0.6 8.4 0.7 0.6 629.0 4.0 1.8 0.5 5.4 0.0 16.8 0.5 0.0 0.2 2.9 0.0 4.9 32.8 1.5 0.7 0.1 0.0 7.7 1.5 3.5 0.6 2.8 0.8 0.5 0.7 3.2 0.1 125.2 0.7 0.0 0.1 0.3 0.4 4.2 0.6 0.4 0.0 0.7 0.1 0.0 134.3 2.8 2.1 0.3 0.0 1.6 1.7 0.1 0.1 0.9 160.2 0.8 0.7 0.5 2.2 1.4 0.1 2.3 0.0 5.9 2.0 3.2 0.8 0.5 0.9 27.6 0.2 0.0 0.2 4.7 2.9 0.0 0.0 1.5 0.2 0.0 0.1 0.0 0.4 9.2 0.3 0.4 0.1 7.8 0.0 0.0 0.4 0.1 0.0 3.4 1.0 0.7 0.4 2.0 34.1 17.3 0.3 12.5 26.8 32.6 27.1 10.6 8.4 5.4 5.5 0.0 0.0 1.3 8.3 0.6 1.4 2.2 0.6 15.4 0.3 0.1 164.7 0.0 1.0 0.0 87.6 1.1 0.2 0.1 1.9 0.1 7.0 0.1 0.1 4.6 1.2 250.2 12.9 0.0 0.5 2.9 5.6 0.5 0.0 2.2 0.4 0.1 19.7 3.3 176.8 0.7 2.0 0.8 3.7 6.3 0.3 2.6 0.0 3.7 0.4 1.0 0.0 7.1 2.0 1.1 1.2 0.4 5.7 1.3 0.1 0.3 0.6 5.5 0.0 51.6 5.7 0.2 1.0 0.1 0.0 0.4 1.7 0.1 0.0 1.8 KAT6A "MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220" ENSG00000083168 "Lysine acetyltransferase 6A" Q92794 8 41929479-42051994 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Repressor, Transferase" "Cancer-related genes, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017023, HPA063266, HPA065052" Supported Supported "Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Nucleoli, Cytosol" "CAB017023: , HPA063266: AB_2684973, HPA065052: AB_2685414" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (3.23e-2)" "unprognostic (2.28e-1)" "unprognostic (9.27e-3)" "unprognostic (3.61e-1)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (1.50e-1)" "unprognostic (4.45e-2)" "unprognostic (4.20e-3)" "unprognostic (1.18e-1)" "unprognostic (2.24e-1)" "unprognostic (8.58e-2)" "unprognostic (2.95e-2)" 14.4 7.1 8.6 15.4 12.7 38.2 12.3 20.1 10.5 13.7 9.7 10.2 9.6 15.6 8.6 13.4 12.0 11.2 9.1 9.1 12.8 9.1 10.0 16.7 16.8 12.7 12.4 21.5 11.7 18.0 6.7 14.9 12.9 11.0 10.6 18.1 9.6 9.7 13.1 16.6 12.1 13.5 8.2 15.7 11.3 11.4 10.1 27.0 14.2 16.0 17.2 12.0 10.7 16.7 19.6 23.2 34.8 21.8 17.8 20.3 9.8 15.4 20.6 17.9 14.2 16.3 11.5 33.4 13.4 19.0 19.5 17.3 27.3 18.6 23.2 16.1 14.4 60.4 14.2 10.3 14.8 27.3 23.6 17.1 19.1 20.4 24.8 14.5 18.8 29.7 36.6 24.2 16.0 10.4 59.9 9.4 12.8 20.4 8.1 37.7 39.1 9.9 11.0 27.1 17.6 16.7 15.8 12.4 13.8 15.8 26.3 12.9 25.5 21.6 15.3 21.1 15.5 16.8 22.1 33.8 12.6 14.1 17.3 2.5 0.8 1.8 1.6 0.9 1.6 1.4 1.6 2.1 0.6 1.6 1.9 1.8 5.1 1.9 0.9 1.1 1.9 1.2 8.6 12.7 20.1 10.5 9.1 12.8 12.7 12.4 12.9 8.2 10.1 16.7 87.5 35.3 34.9 64.0 54.0 50.3 24.2 15.5 18.2 54.8 31.7 25.5 23.7 18.6 25.3 12.9 54.2 14.4 61.5 23.2 3.9 14.2 2.6 30.3 47.5 56.7 24.7 31.2 62.8 11.8 17.0 32.4 21.4 44.8 35.4 31.9 43.5 25.3 17.0 58.9 76.6 24.9 10.2 44.2 34.5 4.8 28.3 43.7 23.2 120.9 30.3 27.9 61.8 93.5 129.2 15.7 20.2 23.0 38.7 30.7 22.9 10.6 22.8 44.9 19.7 49.3 34.6 37.8 37.0 23.0 61.2 21.1 61.4 19.7 19.3 27.2 AP3M2 "AP47B, CLA20" ENSG00000070718 "Adaptor related protein complex 3 subunit mu 2" P53677 8 42152946-42171673 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014876, HPA045591, HPA048380" Approved NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "CAB014876: , HPA045591: AB_2679377, HPA048380: AB_2680379" "unprognostic (5.53e-2)" "unprognostic (2.26e-2)" "unprognostic (3.50e-2)" "prognostic unfavorable (3.46e-4)" "unprognostic (3.33e-1)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (8.20e-2)" "unprognostic (1.13e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-1)" "unprognostic (4.80e-2)" "unprognostic (3.61e-2)" "unprognostic (2.69e-1)" "unprognostic (4.32e-1)" "unprognostic (8.04e-2)" "prognostic favorable (2.38e-4)" 9.1 11.3 26.0 8.0 27.0 11.2 8.8 18.5 27.4 9.2 14.4 8.5 7.2 10.5 13.0 7.0 16.4 10.5 14.1 27.9 25.7 12.4 4.6 12.7 12.4 22.9 21.4 9.5 6.5 22.7 13.3 20.6 24.2 10.3 8.7 41.9 6.2 11.5 8.9 12.6 7.8 9.9 20.8 10.4 7.0 23.6 26.9 8.3 13.5 10.6 10.4 9.9 8.1 21.2 20.6 20.8 18.2 21.4 16.2 15.9 4.0 23.5 23.3 22.0 25.7 11.7 24.4 12.3 14.7 13.5 24.8 23.9 28.6 14.8 28.4 17.0 26.9 23.4 17.8 8.1 14.7 10.1 13.4 14.5 25.1 24.0 13.6 30.5 15.0 35.1 28.5 11.3 20.2 9.7 30.0 11.9 20.4 25.0 14.5 28.6 34.7 13.2 16.8 24.0 25.9 18.6 14.4 7.2 26.1 18.8 21.2 6.4 9.6 13.4 19.2 20.0 10.9 9.6 19.5 11.2 18.8 1.4 37.8 2.9 1.9 1.5 7.5 2.7 9.7 4.7 15.5 8.1 4.2 3.0 14.4 5.7 2.3 7.7 2.8 6.8 5.9 5.0 26.0 27.0 18.5 27.4 27.9 25.7 22.9 21.4 24.2 20.8 26.9 21.2 16.2 12.8 3.3 16.6 13.6 17.5 20.3 8.0 9.1 35.9 6.9 7.4 17.0 1.5 9.3 14.7 39.6 7.0 21.3 2.6 5.9 12.9 59.8 15.7 11.6 18.1 3.0 10.8 26.2 7.4 4.8 11.5 6.6 11.1 3.8 12.1 18.5 4.3 6.6 35.3 33.6 3.0 16.2 2.1 10.1 70.1 5.3 6.5 37.4 14.0 13.5 19.6 11.3 15.1 16.0 16.3 1.8 9.1 17.1 8.9 0.9 6.8 18.8 37.1 19.7 8.1 15.0 26.8 45.0 6.6 19.7 2.9 41.5 11.0 4.3 15.4 PLAT ENSG00000104368 "Plasminogen activator, tissue type" P00750 8 42174718-42207709 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins" "Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 246.0;urinary bladder: 181.4" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 763.3;Urothelial cells: 992.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 604.7;HMC-1: 425.2;hTERT-RPE1: 344.9;LHCN-M2: 298.2;U-2197: 441.2;WM-115: 806.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003412, CAB009335" Supported Approved "Actin filaments" "Secreted to blood" NA NA 9900000 110000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "CAB009335: AB_2237146, HPA003412: AB_1858205" "prognostic favorable (7.57e-4)" "unprognostic (2.23e-1)" "unprognostic (4.08e-1)" "unprognostic (3.39e-1)" "unprognostic (4.88e-3)" "unprognostic (9.39e-2)" "unprognostic (4.65e-3)" "unprognostic (5.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (2.98e-3)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.95e-4)" "unprognostic (8.72e-3)" "unprognostic (1.37e-2)" "unprognostic (2.63e-2)" "unprognostic (6.09e-2)" 58.9 44.0 14.0 35.6 13.7 0.1 35.1 14.6 17.4 21.8 10.3 55.3 29.9 49.6 16.8 33.7 49.8 40.4 19.3 12.5 16.6 91.9 5.3 41.3 2.3 15.4 15.4 21.5 16.0 246.0 13.3 44.4 16.6 54.0 25.0 2.1 15.6 29.1 8.8 6.2 34.6 32.9 16.0 2.0 41.8 11.9 18.8 4.4 30.9 9.8 2.7 181.4 33.1 14.0 4.2 1.4 29.0 9.1 43.1 61.9 0.9 125.8 216.4 54.2 43.4 1.4 604.7 0.0 4.4 17.1 28.4 14.5 0.3 23.9 78.5 64.6 8.4 0.7 1.0 0.6 253.9 0.2 425.2 65.6 0.4 140.3 6.0 344.9 103.9 0.2 4.6 0.8 298.2 0.0 0.6 0.5 42.3 0.3 48.2 0.2 103.5 0.3 12.6 0.4 0.3 7.4 0.2 0.4 158.7 39.7 1.0 0.3 189.3 11.6 43.1 441.2 15.6 0.2 1.1 0.2 9.7 0.2 806.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 14.0 13.7 14.6 17.4 12.5 16.6 15.4 15.4 16.6 16.0 18.8 14.0 63.5 0.0 13.7 0.0 2.9 10.8 763.3 155.9 7.4 4.7 103.9 66.3 7.4 1.5 19.1 0.0 4.2 0.6 0.9 0.1 0.0 9.3 0.9 4.8 104.2 98.2 0.0 0.0 1.6 0.6 1.3 136.5 2.0 5.1 164.0 89.7 36.4 0.8 1.9 1.7 4.0 0.0 4.1 1.0 17.7 1.5 3.7 4.7 23.2 25.3 1.6 2.1 1.0 42.7 0.3 52.0 0.0 2.6 2.8 193.3 0.2 0.3 4.0 3.8 13.1 10.8 48.3 1.1 0.6 13.6 13.5 0.7 6.0 0.5 0.5 992.1 IKBKB "IKK-beta, IKK2, IKKB, NFKBIKB" ENSG00000104365 "Inhibitor of nuclear factor kappa B kinase subunit beta" O14920 8 42271302-42332460 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001249, CAB004447" Enhanced Supported Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "CAB004447: AB_627785, HPA001249: AB_1079126" "unprognostic (1.04e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-3)" "unprognostic (1.26e-1)" "unprognostic (1.27e-3)" "unprognostic (1.95e-1)" "unprognostic (1.25e-3)" "unprognostic (1.75e-1)" "unprognostic (1.55e-1)" "unprognostic (3.27e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-2)" "unprognostic (1.89e-2)" "unprognostic (9.20e-2)" "unprognostic (3.02e-1)" "prognostic favorable (1.46e-6)" 9.4 8.2 9.1 4.7 9.8 4.8 8.3 9.2 10.9 7.2 11.7 6.8 4.8 8.1 7.3 10.2 11.6 8.6 5.6 9.2 9.5 6.8 6.6 11.3 12.2 10.5 9.9 6.1 6.2 13.5 4.0 8.2 10.0 7.9 6.8 12.3 8.9 9.3 13.7 11.4 4.9 12.7 9.7 10.5 5.5 3.2 10.1 10.8 9.4 24.3 11.6 11.1 6.8 10.2 6.2 15.7 8.0 13.6 17.3 18.9 5.8 9.2 18.2 15.2 17.2 3.1 13.9 14.1 10.0 16.5 12.5 5.6 8.4 18.3 17.8 9.8 10.8 17.8 7.8 5.9 20.9 6.1 24.0 12.3 13.7 15.0 19.1 36.1 20.7 11.6 12.8 6.9 34.6 5.1 13.9 11.3 6.1 18.9 6.0 11.1 15.3 10.0 19.6 5.7 1.3 4.7 6.4 6.4 11.7 10.0 8.7 23.6 13.6 7.2 3.9 13.9 6.1 2.8 4.0 10.3 13.8 7.6 16.7 7.4 5.0 5.6 4.6 4.1 4.3 4.4 5.1 5.5 3.7 4.8 4.8 4.7 5.2 5.1 5.5 8.5 5.9 2.9 9.1 9.8 9.2 10.9 9.2 9.5 10.5 9.9 10.0 9.7 10.1 10.2 31.3 12.8 26.9 19.2 28.4 24.3 34.1 13.9 25.6 12.7 20.6 15.5 8.8 14.3 15.4 16.5 135.5 10.4 34.1 15.9 1.9 13.4 2.3 13.9 15.6 27.4 11.4 10.1 19.7 13.6 5.3 12.4 21.9 16.5 38.0 24.0 19.6 12.0 18.6 18.5 20.6 16.4 8.2 32.3 24.0 3.4 16.4 23.4 19.6 58.1 33.7 8.7 47.4 17.1 30.2 16.6 15.0 12.8 18.2 31.9 13.2 5.5 20.2 47.9 6.6 13.1 11.4 4.8 7.0 17.8 29.1 15.2 24.3 6.2 14.1 30.8 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.5;Late spermatids: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 280.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013" Enhanced Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB011616: AB_731977, HPA049104: AB_2680632, HPA069013: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.65e-4)" 12.4 17.5 26.6 13.5 27.4 51.3 27.4 82.3 35.5 18.9 24.3 12.3 10.8 12.9 19.7 26.5 13.2 17.4 26.1 28.1 29.0 18.0 33.9 14.2 20.2 27.1 27.8 20.4 16.9 18.8 26.7 11.1 28.9 24.8 13.2 18.0 30.3 11.3 85.3 23.1 10.8 10.6 27.6 17.2 14.0 53.1 30.2 24.8 14.2 70.0 22.2 30.8 18.9 28.9 40.2 23.5 40.6 80.4 21.8 20.7 33.8 25.2 29.3 41.5 37.7 33.1 46.0 36.4 31.1 16.5 43.4 20.0 34.1 29.5 50.3 23.8 36.7 26.5 18.2 45.3 34.1 18.6 280.6 18.8 34.4 30.1 35.4 51.8 32.1 77.2 58.4 22.4 40.3 23.6 78.0 52.6 54.4 48.4 26.7 44.2 40.8 31.4 78.4 32.1 22.7 41.8 29.9 19.9 79.0 41.4 52.5 31.5 17.8 19.1 27.0 48.8 24.6 32.5 58.4 52.2 19.3 39.4 52.2 47.6 15.1 48.1 12.0 18.8 13.3 12.2 12.5 13.0 15.7 11.1 14.1 13.3 63.6 22.2 26.3 84.9 19.3 11.5 26.6 27.4 82.3 35.5 28.1 29.0 27.1 27.8 28.9 27.6 30.2 28.9 13.9 3.2 13.6 6.8 20.2 16.8 30.1 14.2 31.3 2.9 14.3 15.1 21.6 7.2 20.7 7.3 8.4 7.5 51.9 3.1 5.9 11.7 254.5 13.8 7.7 12.5 6.0 7.6 15.8 9.6 7.0 9.7 10.2 9.9 23.4 12.7 8.6 12.7 7.4 6.7 20.3 5.4 4.1 5.7 9.9 133.9 7.2 18.2 7.2 19.7 11.2 8.3 13.4 12.5 16.7 33.6 5.8 3.8 21.9 41.6 4.3 6.8 16.4 4.4 0.0 6.6 12.3 19.4 15.4 27.3 20.0 11.1 16.2 7.8 6.6 31.6 DKK4 ENSG00000104371 "Dickkopf WNT signaling pathway inhibitor 4" Q9UBT3 8 42374063-42377229 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.7;esophagus: 4.9" "Group enriched" "Detected in some" 5 "Basal prostatic cells: 5.2;Early spermatids: 2.1;Pancreatic endocrine cells: 4.4;Prostatic glandular cells: 3.7;Spermatocytes: 2.2;Urothelial cells: 5.3" "Cancer enriched" "Detected in many" 20 "endometrial cancer: 174.4" "Group enriched" "Detected in some" 4 "cerebellum: 3.7;midbrain: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "OE19: 20.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052916 Uncertain "Secreted in other tissues" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA052916: AB_2681987" "unprognostic (1.64e-1)" "unprognostic (5.84e-2)" "unprognostic (1.97e-1)" "unprognostic (5.37e-3)" "unprognostic (3.23e-1)" "unprognostic (2.91e-2)" "unprognostic (2.13e-2)" "unprognostic (1.99e-1)" "unprognostic (6.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.63e-2)" "unprognostic (6.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.53e-1)" "unprognostic (8.11e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 0.8 3.7 0.1 1.0 0.0 0.0 2.4 0.0 0.7 4.9 0.3 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.7 3.1 0.0 0.0 0.0 0.9 0.0 0.6 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.4 0.3 0.0 0.0 0.8 1.4 0.5 0.3 0.0 0.0 0.4 1.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.1 0.0 0.1 0.7 3.1 0.6 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.3 5.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.4 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 5.3 VDAC3 HD-VDAC3 ENSG00000078668 "Voltage dependent anion channel 3" Q9Y277 8 42391624-42405937 "Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Porin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 385.2;skeletal muscle: 914.4;tongue: 942.7" "Cell type enhanced" "Detected in all" "Spermatocytes: 403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026864 Uncertain Supported Mitochondria NA NA 1200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA026864: AB_1858733" "unprognostic (2.55e-2)" "unprognostic (1.96e-2)" "unprognostic (9.88e-3)" "unprognostic (4.40e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-1)" "unprognostic (4.98e-2)" "unprognostic (2.25e-2)" "unprognostic (1.40e-2)" "unprognostic (5.76e-2)" "unprognostic (3.74e-1)" "unprognostic (1.19e-2)" "unprognostic (6.16e-3)" "unprognostic (2.96e-2)" "unprognostic (1.76e-1)" "unprognostic (8.78e-3)" "unprognostic (6.94e-3)" 67.5 76.2 117.3 59.1 119.4 92.1 70.3 116.8 150.6 53.7 115.4 106.9 79.8 63.5 68.6 99.9 85.8 56.0 385.2 121.1 130.8 108.8 92.9 51.9 66.3 122.7 119.3 61.6 64.6 92.4 58.9 63.9 139.2 69.5 106.4 123.1 61.6 81.3 914.4 54.1 73.0 92.8 114.1 67.3 72.1 114.5 118.6 80.1 83.3 942.7 79.3 78.9 59.8 113.8 226.3 225.7 174.5 185.9 146.3 126.6 84.8 180.0 151.1 225.4 205.2 173.4 190.4 235.8 165.0 153.7 196.3 142.5 238.4 194.1 244.7 117.2 196.6 352.9 138.4 250.2 105.2 172.0 190.1 98.6 143.3 171.6 80.9 149.6 279.8 201.3 284.4 158.6 235.7 126.4 373.3 197.1 205.2 285.6 144.5 193.6 322.1 165.3 245.7 198.8 156.8 133.3 112.1 132.8 116.1 126.4 279.9 129.9 149.8 86.6 150.0 217.7 174.0 145.2 264.1 266.9 117.5 238.0 150.9 142.8 165.3 183.4 145.8 167.2 148.7 126.5 155.6 146.5 222.7 96.6 152.7 147.7 82.8 125.8 155.6 163.0 202.5 360.5 117.3 119.4 116.8 150.6 121.1 130.8 122.7 119.3 139.2 114.1 118.6 113.8 78.1 44.8 24.4 50.6 59.8 64.5 81.1 197.8 58.1 85.9 53.0 73.9 321.2 55.8 82.8 66.2 35.5 145.5 91.9 65.7 307.2 116.3 151.1 112.8 56.7 70.5 47.8 186.4 63.2 90.0 112.1 81.5 41.3 47.1 55.2 100.6 68.2 60.4 139.7 138.0 78.9 86.1 177.0 58.5 77.8 146.4 69.3 107.7 72.9 26.2 130.1 72.9 83.4 38.2 34.7 84.9 86.7 97.4 75.9 48.9 125.3 177.5 142.1 94.5 65.7 146.4 123.8 403.7 156.3 82.3 70.8 58.3 79.7 94.2 124.8 70.4 SLC20A2 "Glvr-2, GLVR2, MLVAR, PiT-2, Ram-1" ENSG00000168575 "Solute carrier family 20 member 2" Q08357 8 42416475-42541926 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Host-virus interaction, Ion transport, Phosphate transport, Sodium transport, Symport, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 130.6;skeletal muscle: 131.2" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 250.2;Oligodendrocytes: 151.7;Urothelial cells: 170.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CAPAN-2: 132.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026540 Approved NA NA "Cluster 15: NK-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "HPA026540: AB_1855408" "prognostic unfavorable (7.67e-4)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.27e-2)" "unprognostic (2.12e-2)" "unprognostic (2.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (2.95e-1)" "unprognostic (7.62e-2)" "unprognostic (2.06e-1)" "unprognostic (3.43e-2)" "prognostic favorable (1.01e-4)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (5.86e-2)" "unprognostic (4.95e-2)" 11.9 8.0 33.4 9.8 45.3 3.0 12.1 55.4 37.1 15.8 130.6 22.8 46.7 18.5 9.9 32.7 24.5 15.1 63.2 30.1 48.7 17.5 39.7 15.1 6.5 46.5 56.5 8.1 51.6 15.0 10.5 13.5 47.5 13.6 19.0 7.5 87.9 17.6 131.2 23.3 18.8 17.9 42.7 7.4 15.1 15.9 67.8 11.9 82.8 57.6 9.1 22.0 21.7 52.8 52.7 14.3 19.0 16.0 10.4 8.8 41.1 46.9 80.8 23.9 58.7 38.9 132.9 17.4 53.6 42.1 13.5 81.1 11.4 45.2 41.6 4.3 8.7 27.8 4.8 22.0 14.9 9.9 12.3 9.5 40.2 24.7 22.7 16.7 12.0 13.7 27.2 14.0 47.3 14.4 18.1 16.1 19.2 50.5 8.8 14.9 20.9 18.5 21.4 47.5 5.1 19.2 12.8 21.8 12.8 15.0 17.5 17.3 34.9 50.0 17.4 12.3 25.7 9.0 22.2 12.6 15.8 19.5 28.3 3.2 2.2 0.2 3.6 1.6 4.3 2.1 4.0 3.5 3.7 2.1 4.8 3.7 0.8 6.8 1.3 2.0 4.1 3.1 33.4 45.3 55.4 37.1 30.1 48.7 46.5 56.5 47.5 42.7 67.8 52.8 11.1 28.9 18.6 51.6 9.1 98.9 250.2 22.7 96.2 13.4 21.7 14.9 60.2 14.3 21.7 16.5 16.7 23.9 14.3 76.2 13.7 29.6 10.4 79.9 15.8 18.9 12.0 6.9 88.9 31.4 23.7 15.8 15.8 61.2 3.8 17.1 6.4 30.7 10.2 6.7 88.4 11.5 18.3 7.7 12.2 10.0 7.2 10.2 10.6 78.7 7.3 14.4 14.4 63.3 151.7 47.4 35.8 11.7 8.6 76.6 20.0 7.3 57.6 10.2 6.6 22.9 28.3 5.2 7.2 73.9 74.3 25.4 14.2 23.7 12.5 170.3 SMIM19 C8orf40 ENSG00000176209 "Small integral membrane protein 19" Q96E16 8 42541155-42555195 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011145, HPA074830" Uncertain Approved "Nuclear speckles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 2: Karpas-707 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "HPA011145: AB_1078360, HPA074830: " "unprognostic (2.12e-2)" "unprognostic (2.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.85e-2)" "unprognostic (1.42e-1)" "unprognostic (6.68e-3)" "unprognostic (7.04e-3)" "unprognostic (1.76e-2)" "unprognostic (4.84e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.67e-2)" "prognostic favorable (1.74e-6)" "unprognostic (5.10e-2)" "unprognostic (9.70e-3)" "unprognostic (9.64e-2)" "unprognostic (2.93e-3)" 55.2 57.1 34.7 18.4 35.4 32.5 64.9 35.8 44.3 31.9 35.8 41.7 30.0 32.6 80.0 33.2 57.0 27.8 59.6 36.1 35.8 76.9 136.8 31.5 36.9 34.2 34.9 42.2 68.5 36.2 26.8 23.3 35.1 31.9 34.6 21.1 62.6 30.1 121.8 44.8 38.9 25.1 35.7 33.3 46.2 43.9 35.0 36.6 73.5 74.1 33.9 36.4 29.9 37.3 38.9 28.5 61.0 52.6 35.9 43.2 19.9 29.9 40.2 23.4 27.8 6.8 84.4 42.4 12.2 25.1 57.0 27.2 31.8 19.2 24.3 33.8 26.3 35.9 17.9 15.5 73.9 25.7 9.0 35.4 16.1 19.6 62.7 45.3 21.5 49.1 28.8 94.5 23.7 38.0 18.8 39.0 72.1 90.4 19.5 21.1 43.4 72.4 60.7 28.5 12.7 46.0 30.0 32.2 93.1 32.6 68.0 48.2 27.3 14.7 12.5 40.8 19.6 88.7 53.8 56.9 62.2 40.9 39.6 92.2 42.3 31.4 46.3 34.0 56.5 71.3 59.6 57.0 65.1 68.3 55.6 54.3 15.3 80.7 28.8 107.2 78.2 40.0 34.7 35.4 35.8 44.3 36.1 35.8 34.2 34.9 35.1 35.7 35.0 37.3 53.1 22.4 45.9 5.9 43.0 45.8 63.5 89.8 70.6 25.2 89.9 108.8 75.7 88.6 66.2 33.1 6.2 90.1 58.6 36.2 201.5 67.9 183.9 109.6 26.0 43.9 16.3 45.6 12.7 126.8 62.9 65.5 43.3 54.8 40.0 52.3 47.8 142.5 78.3 23.5 13.4 74.4 61.1 45.9 51.0 77.5 69.0 47.3 92.5 11.2 64.0 66.7 42.2 10.6 14.6 85.5 69.5 59.5 29.0 53.3 161.9 228.2 110.9 14.3 26.3 67.6 50.7 131.3 48.6 58.4 49.6 47.2 43.3 76.4 74.8 63.2 CHRNB3 ENSG00000147432 "Cholinergic receptor nicotinic beta 3 subunit" Q05901 8 42697366-42737407 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 12.1;retina: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Bipolar cells: 1.5;Excitatory neurons: 2.2;Inhibitory neurons: 2.9;Microglial cells: 1.0;Rod photoreceptor cells: 1.1" "Cancer enriched" "Detected in single" 11 "testis cancer: 0.6" "Group enriched" "Detected in many" 5 "cerebellum: 12.1;midbrain: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "NTERA-2: 1.1;U-266/84: 2.7" "Region enhanced" "Detected in many" "midbrain: 6.9" "Low region specificity" "Detected in all" HPA045555 Enhanced NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA045555: AB_10960891" "unprognostic (8.63e-2)" "unprognostic (4.12e-1)" "unprognostic (7.29e-2)" "unprognostic (1.62e-1)" 0.0 0.0 0.2 0.0 1.7 0.0 0.0 12.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.0 0.0 0.0 0.1 0.0 10.2 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 1.7 12.1 0.3 0.5 2.2 0.0 10.2 0.2 0.0 0.4 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CHRNA6 ENSG00000147434 "Cholinergic receptor nicotinic alpha 6 subunit" Q15825 8 42752620-42796392 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 9.3;retina: 3.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.0;Inhibitory neurons: 2.6;Late spermatids: 1.9;Rod photoreceptor cells: 1.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebellum: 9.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.2;HDLM-2: 2.7;HMC-1: 1.2;JURKAT: 1.2;RPMI-8226: 1.0;U-698: 3.6" "Group enriched" "Detected in many" 7 "midbrain: 20.2;thalamus: 6.3" "Region enriched" "Detected in all" 6 "midbrain: 76.1" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.91e-1)" "unprognostic (7.49e-2)" "unprognostic (2.66e-3)" "unprognostic (1.25e-2)" "unprognostic (5.23e-2)" "unprognostic (7.60e-4)" "unprognostic (4.99e-2)" "unprognostic (2.48e-2)" "unprognostic (7.73e-2)" "unprognostic (6.24e-2)" "unprognostic (2.13e-1)" "unprognostic (6.56e-2)" "unprognostic (2.63e-1)" "unprognostic (3.97e-2)" "unprognostic (1.92e-1)" "unprognostic (3.27e-3)" "unprognostic (3.66e-2)" 0.0 0.3 0.5 0.1 0.7 0.0 0.1 9.3 0.4 0.2 1.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.2 0.0 0.1 0.1 1.7 2.9 0.1 0.0 0.0 0.1 0.0 0.8 0.0 0.0 3.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.6 0.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.5 0.7 9.3 0.4 0.2 0.2 1.7 2.9 0.8 0.0 3.8 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.0 2.6 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 THAP1 "4833431A01Rik, DYT6, FLJ10477" ENSG00000131931 "THAP domain containing 1" Q9NVV9 8 42836674-42843325 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" DNA-binding "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071310 Supported Nucleoplasm No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "HPA071310: AB_2686386" "unprognostic (8.99e-3)" "unprognostic (3.97e-3)" "unprognostic (7.15e-3)" "unprognostic (1.87e-2)" "unprognostic (2.55e-1)" "unprognostic (6.38e-2)" "unprognostic (1.20e-1)" "unprognostic (4.03e-1)" "unprognostic (3.91e-2)" "unprognostic (5.95e-2)" "unprognostic (9.43e-2)" "unprognostic (9.19e-2)" "unprognostic (2.94e-2)" "unprognostic (1.28e-1)" "unprognostic (2.82e-1)" "unprognostic (1.95e-1)" "unprognostic (3.16e-2)" 7.3 5.7 4.9 6.9 5.1 8.3 7.4 7.3 7.5 6.2 4.9 6.2 5.9 6.9 6.2 6.3 7.3 5.1 8.8 4.9 4.7 7.0 8.7 5.4 9.5 5.2 4.8 8.2 4.6 7.9 3.8 7.0 5.3 5.7 5.4 5.7 6.2 5.7 12.4 4.0 5.8 6.8 5.2 6.3 5.0 9.4 5.2 11.5 8.6 12.5 8.4 6.5 3.7 6.4 10.5 9.3 8.5 8.2 12.7 14.3 10.2 14.2 10.8 12.8 11.7 8.0 13.2 12.8 11.3 10.5 19.0 10.7 14.0 12.0 16.2 12.4 10.3 12.5 8.1 9.4 15.6 10.4 12.7 11.3 17.7 14.1 18.2 12.4 16.5 17.1 14.1 14.7 15.1 6.4 25.1 12.1 16.8 16.9 7.4 11.2 15.2 10.2 13.9 7.8 6.9 8.1 15.5 9.7 20.2 11.2 13.5 11.6 10.0 11.2 8.3 15.0 14.3 11.9 14.0 12.2 11.2 13.6 12.4 23.8 18.6 30.8 19.9 16.7 21.6 20.4 23.1 22.1 19.9 17.8 26.9 21.5 22.0 19.3 18.0 9.8 32.5 18.8 4.9 5.1 7.3 7.5 4.9 4.7 5.2 4.8 5.3 5.2 5.2 6.4 17.2 9.6 9.4 3.6 20.1 13.5 9.4 16.6 26.7 10.5 12.3 11.4 21.5 7.2 12.6 5.5 0.0 20.5 17.5 7.7 23.5 17.5 35.6 16.1 16.2 15.5 14.3 18.3 5.2 11.3 23.8 14.5 2.6 13.3 16.5 8.6 10.4 12.1 15.2 23.5 5.3 8.8 28.5 11.6 9.2 17.9 11.5 13.4 7.2 2.8 20.2 15.6 30.9 5.5 4.9 10.6 4.0 13.9 18.5 10.8 14.1 22.9 13.1 11.0 0.0 12.9 17.0 32.6 45.8 21.1 13.8 8.1 24.6 12.8 9.6 8.2 RNF170 "ADSA, DKFZP564A022, SNAX1" ENSG00000120925 "Ring finger protein 170" Q96K19 8 42849637-42897290 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050931, HPA054621" Uncertain NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "HPA050931: AB_2681279, HPA054621: AB_2682545" "unprognostic (3.06e-2)" "unprognostic (4.20e-1)" "unprognostic (9.54e-2)" "unprognostic (6.37e-2)" "unprognostic (4.59e-2)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.59e-1)" "unprognostic (3.03e-2)" "unprognostic (1.61e-3)" "unprognostic (4.13e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.13e-1)" 9.3 11.7 14.5 7.5 15.6 2.4 12.7 16.3 16.8 7.9 11.5 11.1 10.3 9.5 14.9 14.2 9.3 9.2 7.7 14.1 15.8 16.4 19.7 9.3 9.4 15.9 15.5 12.3 8.1 13.5 9.5 19.2 16.2 11.0 11.3 35.6 11.0 10.6 11.9 15.1 11.4 7.6 15.0 9.1 10.7 5.9 15.6 6.1 28.8 9.2 9.9 7.6 8.5 18.3 11.4 18.1 18.2 9.2 29.4 29.7 10.8 13.3 18.1 12.3 13.2 8.5 36.0 13.6 15.7 12.8 22.1 9.6 9.6 13.2 10.8 9.4 10.4 15.9 8.5 9.3 16.1 2.0 10.9 26.0 20.4 9.3 18.8 16.0 13.3 15.0 14.6 15.8 19.9 3.4 17.0 9.5 8.6 24.1 6.5 8.7 24.2 7.7 19.6 10.8 4.7 14.3 12.8 8.9 23.0 17.7 23.1 9.5 19.5 13.2 5.8 17.8 4.3 25.2 26.4 15.7 18.2 6.7 13.6 1.4 5.7 2.1 2.9 5.7 4.2 6.6 4.8 5.3 8.8 3.9 5.6 4.1 0.6 4.9 5.5 8.9 6.7 4.5 14.5 15.6 16.3 16.8 14.1 15.8 15.9 15.5 16.2 15.0 15.6 18.3 13.5 48.1 20.5 41.1 16.1 7.6 13.1 22.3 5.7 44.8 14.9 9.5 11.5 15.7 29.2 23.9 89.6 41.6 9.8 22.1 17.6 21.6 1.7 16.0 14.5 15.2 13.1 5.5 36.7 27.8 19.4 20.0 11.2 13.3 9.5 25.5 21.8 21.7 22.9 21.9 43.7 15.3 20.3 18.5 9.2 2.4 15.2 15.4 8.8 15.9 21.9 31.8 30.9 36.2 75.9 32.2 18.4 20.7 10.7 9.6 34.5 22.1 33.3 72.1 13.1 23.9 12.1 14.9 19.3 12.5 11.5 31.2 12.8 25.7 16.6 12.2 HOOK3 HK3 ENSG00000168172 "Hook microtubule tethering protein 3" Q86VS8 8 42896946-43030535 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024756 Approved Supported "Golgi apparatus,Centriolar satellite,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Centriolar satellite" "Golgi apparatus, Cytosol" "HPA024756: AB_1850913" "unprognostic (1.84e-2)" "unprognostic (1.61e-1)" "unprognostic (2.73e-1)" "unprognostic (8.61e-3)" "unprognostic (6.05e-2)" "unprognostic (1.77e-3)" "unprognostic (2.36e-1)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-1)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.63e-1)" "unprognostic (3.78e-1)" "unprognostic (2.55e-1)" "unprognostic (7.12e-2)" 9.8 6.2 3.1 7.4 8.7 11.1 8.9 11.9 8.9 8.2 1.5 7.5 7.5 8.3 8.2 10.6 7.0 14.4 4.6 4.0 11.1 6.6 7.3 8.0 6.6 7.6 4.9 6.1 7.6 7.2 4.1 8.6 7.3 12.4 7.7 8.8 9.6 7.1 10.6 8.1 8.9 6.7 4.4 6.6 9.5 11.4 4.9 6.4 21.7 8.2 7.4 9.3 6.0 15.5 11.2 10.9 26.2 14.2 19.0 16.7 10.1 14.0 11.6 11.5 10.7 14.5 12.8 13.9 13.9 18.8 10.9 6.4 22.1 9.5 18.5 9.5 6.4 26.3 9.2 10.2 10.6 2.8 14.9 13.7 6.6 15.4 13.2 15.9 16.7 9.7 14.7 15.9 14.0 2.7 21.7 5.2 9.5 8.8 3.3 12.6 27.3 3.5 8.6 16.5 6.7 10.6 15.9 6.7 7.4 11.4 12.2 9.4 30.2 17.1 13.2 20.9 9.0 15.6 18.6 18.1 14.5 9.9 25.8 9.4 2.0 2.0 1.2 2.0 0.4 0.9 1.1 0.9 2.4 0.9 0.6 0.8 2.2 1.2 1.9 1.4 0.8 1.1 3.1 8.7 11.9 8.9 4.0 11.1 7.6 4.9 7.3 4.4 4.9 15.5 75.3 93.0 60.6 90.1 43.2 68.3 36.2 28.7 43.3 40.1 29.4 22.4 48.2 44.3 43.6 25.8 33.3 43.6 40.6 26.1 27.4 47.1 120.3 60.0 84.0 65.2 65.4 34.5 102.1 32.8 25.9 65.8 33.1 93.8 53.8 37.9 60.3 36.4 38.0 75.7 107.6 26.9 20.3 79.4 96.4 36.3 44.7 82.8 55.2 78.7 118.6 36.3 37.0 119.1 157.8 59.7 27.6 53.8 43.6 43.5 37.3 21.4 35.2 32.2 65.7 63.4 74.6 28.0 21.5 39.8 74.7 113.7 40.9 42.6 16.2 71.1 FNTA "FPTA, PGGT1A, PTAR2" ENSG00000168522 "Farnesyltransferase, CAAX box, alpha" P49354 8 43034194-43085788 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Prenyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010149, HPA018830" Approved Approved Cytosol NA NA 170000 "Cluster 26: Non-specific - Mitochondria" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "CAB010149: AB_2106299, HPA018830: AB_1848992" "unprognostic (2.09e-1)" "unprognostic (1.35e-1)" "unprognostic (2.90e-1)" "unprognostic (1.86e-3)" "unprognostic (2.64e-1)" "unprognostic (4.70e-3)" "unprognostic (1.83e-2)" "unprognostic (3.69e-2)" "unprognostic (1.70e-2)" "unprognostic (5.37e-2)" "unprognostic (3.25e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (2.94e-12)" "unprognostic (3.63e-2)" "unprognostic (2.33e-1)" "unprognostic (3.19e-2)" "unprognostic (1.29e-3)" 53.6 33.4 57.7 26.3 69.3 26.8 46.1 74.0 74.0 41.3 52.7 46.3 35.9 34.0 43.2 45.4 33.4 27.1 48.1 54.2 63.7 37.4 47.2 34.7 45.5 75.1 64.8 33.0 43.9 34.3 36.6 50.0 73.6 38.3 32.5 33.8 36.5 34.1 74.3 51.0 32.9 31.4 73.2 36.7 35.4 26.9 61.9 39.9 31.6 64.7 44.2 40.9 43.1 87.6 78.8 37.5 50.9 16.7 88.6 112.5 43.4 44.9 52.4 50.1 46.3 62.1 56.9 88.5 35.5 54.1 67.6 41.9 63.1 71.5 59.4 26.2 42.2 70.9 25.5 54.2 112.7 30.4 35.8 87.6 119.0 36.3 104.2 74.4 89.4 47.9 86.1 50.4 58.5 9.9 72.3 47.1 91.3 66.4 27.1 63.1 83.0 47.8 70.5 58.4 29.7 47.4 56.6 47.3 78.9 59.1 59.1 55.3 69.9 17.9 22.1 68.6 48.0 47.7 46.2 89.2 43.0 56.4 41.3 3.1 7.7 14.3 9.5 10.7 11.3 14.1 9.7 12.6 13.3 15.2 12.9 12.9 4.3 16.1 7.8 12.6 14.3 6.4 57.7 69.3 74.0 74.0 54.2 63.7 75.1 64.8 73.6 73.2 61.9 87.6 68.7 57.7 20.3 33.0 57.4 87.7 82.3 55.3 58.1 22.5 35.5 34.8 44.9 34.3 41.2 33.1 37.5 135.6 69.1 29.6 70.5 73.0 41.2 40.7 55.1 55.8 32.2 38.9 27.9 70.1 124.4 58.7 28.5 46.2 32.4 58.6 56.0 25.9 80.5 20.2 31.9 39.6 34.6 47.5 60.7 52.8 48.1 49.2 94.3 33.7 75.7 42.8 69.0 25.6 79.8 69.4 41.2 60.2 40.8 109.3 67.0 54.8 46.7 57.5 52.6 56.2 47.2 65.9 37.1 73.9 95.6 207.6 60.4 69.6 49.1 76.6 POMK "FLJ23356, SgK196" ENSG00000185900 "Protein O-mannose kinase" Q9H5K3 8 43093498-43131180 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Inhibitory neurons: 6.8;Microglial cells: 7.5;Oligodendrocyte precursor cells: 5.5;Oligodendrocytes: 6.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013321 Uncertain NA NA "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "HPA013321: AB_2668809" "unprognostic (1.66e-2)" "unprognostic (1.12e-2)" "unprognostic (1.27e-1)" "unprognostic (4.37e-2)" "unprognostic (1.29e-1)" "unprognostic (4.62e-2)" "unprognostic (5.56e-2)" "unprognostic (2.42e-1)" "unprognostic (2.50e-1)" "unprognostic (8.10e-2)" "unprognostic (1.23e-3)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (7.09e-2)" "unprognostic (1.06e-1)" "unprognostic (3.71e-3)" "unprognostic (2.10e-2)" 2.3 2.8 11.6 2.5 12.6 6.8 3.8 6.0 14.5 4.1 0.0 3.3 1.6 2.3 7.2 1.9 2.4 1.9 1.3 12.3 7.9 2.0 3.3 2.6 4.0 8.8 7.6 2.6 3.3 2.6 0.9 3.1 9.1 5.0 3.6 5.9 2.4 2.4 2.8 5.8 1.8 2.6 6.1 3.9 3.2 3.6 11.1 4.9 3.1 2.7 4.1 2.7 0.8 8.8 7.8 9.1 9.2 24.4 8.8 6.6 9.1 4.3 4.7 6.1 6.1 8.4 13.8 9.2 7.7 7.1 2.5 8.2 13.5 11.7 7.9 2.0 4.3 19.2 6.2 15.6 8.3 6.1 9.9 8.7 15.2 11.1 10.8 4.6 9.1 10.1 4.6 15.9 9.7 5.3 14.5 18.6 19.8 11.2 1.7 8.7 10.2 4.1 19.1 11.3 6.5 8.2 12.4 7.5 10.0 10.7 14.9 9.6 9.8 11.6 12.8 11.8 8.1 5.8 11.6 11.7 5.7 6.3 16.0 2.2 0.9 0.8 0.8 0.8 0.9 0.5 0.8 0.8 1.4 1.2 1.0 1.1 2.8 0.9 1.5 2.4 1.2 0.6 11.6 12.6 6.0 14.5 12.3 7.9 8.8 7.6 9.1 6.1 11.1 8.8 0.6 0.0 0.5 2.9 0.7 0.4 0.1 0.3 1.8 1.6 0.3 0.3 0.3 0.0 1.3 0.0 0.0 0.4 1.0 0.5 0.0 0.2 0.0 0.7 1.9 0.3 0.0 0.4 6.9 0.0 0.8 0.6 1.5 1.0 0.0 1.2 0.0 0.3 0.2 0.0 6.8 0.3 0.0 0.3 0.0 0.0 0.6 0.8 1.8 7.5 1.3 0.3 2.1 5.5 6.5 0.2 0.0 0.0 1.5 0.2 0.5 0.1 0.0 1.0 0.0 0.2 0.6 0.3 1.1 2.3 0.1 0.5 0.9 0.6 0.5 0.2 HGSNAT "FLJ32731, HGNAT, TMEM76" ENSG00000165102 "Heparan-alpha-glucosaminide N-acetyltransferase" Q68CP4 8 43140464-43202855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant, Mucopolysaccharidosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029578 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "HPA029578: AB_10602423" "unprognostic (5.35e-2)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.46e-4)" "unprognostic (3.94e-3)" "unprognostic (1.10e-1)" "unprognostic (6.54e-3)" "unprognostic (5.02e-2)" "prognostic favorable (6.33e-5)" "unprognostic (2.55e-2)" "unprognostic (5.48e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (1.72e-1)" "unprognostic (3.45e-2)" 32.3 20.0 13.1 17.5 13.0 21.7 27.8 10.6 13.5 35.0 13.8 25.4 18.4 30.1 30.6 24.0 29.0 25.9 23.3 13.3 17.6 20.0 26.6 24.5 11.7 13.3 12.0 35.9 29.9 22.7 30.7 28.4 13.2 26.9 17.2 12.5 25.9 23.3 14.4 35.4 20.9 25.1 11.4 17.6 23.2 7.6 15.8 11.3 26.9 17.6 15.7 25.2 28.7 13.0 27.4 36.0 8.9 18.0 71.7 53.8 13.3 30.5 36.2 21.8 19.3 5.1 39.2 14.8 20.5 42.9 15.2 15.5 4.0 18.5 12.7 6.4 6.9 16.3 22.2 8.1 23.0 3.7 2.5 36.2 25.9 11.7 24.9 34.5 39.2 7.0 7.5 22.1 40.4 10.0 14.8 7.2 8.0 16.3 5.4 1.6 16.1 7.7 36.1 22.8 4.7 14.0 39.0 12.6 17.4 19.0 43.7 20.9 46.3 33.2 5.4 20.9 12.7 17.9 18.2 6.1 26.8 6.3 20.8 0.2 8.8 9.4 2.7 5.4 3.0 1.9 2.3 2.8 15.8 2.1 1.7 1.9 3.2 8.8 8.6 2.0 1.7 5.0 13.1 13.0 10.6 13.5 13.3 17.6 13.3 12.0 13.2 11.4 15.8 13.0 39.1 16.0 31.9 48.0 26.7 18.0 19.5 22.6 8.6 50.6 23.9 21.7 10.5 28.6 17.8 51.5 50.1 39.2 30.1 27.2 3.9 26.7 0.5 23.5 42.1 37.8 24.1 15.3 61.8 28.1 39.4 34.3 32.6 36.5 8.2 51.2 49.6 23.5 29.2 25.2 76.3 28.0 18.3 34.3 58.8 3.2 35.1 43.3 19.6 44.0 33.5 13.5 34.0 50.8 43.8 29.9 17.0 31.6 19.8 20.7 31.4 9.9 23.5 39.6 26.3 30.2 28.2 1.1 3.0 22.3 21.2 30.1 25.0 37.4 21.7 17.7 SPIDR KIAA0146 ENSG00000164808 "Scaffold protein involved in DNA repair" Q14159 8 47260878-47736306 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 122.4;Excitatory neurons: 255.4;Inhibitory neurons: 214.4;Microglial cells: 216.4;Oligodendrocyte precursor cells: 207.6;Oligodendrocytes: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027201, HPA041582" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 64: Macrophages - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA027201: AB_10603774, HPA041582: AB_2677563" "unprognostic (5.58e-2)" "unprognostic (2.24e-2)" "unprognostic (2.71e-2)" "unprognostic (7.45e-2)" "unprognostic (4.72e-3)" "unprognostic (7.99e-2)" "unprognostic (3.17e-2)" "unprognostic (2.15e-3)" "unprognostic (2.93e-2)" "prognostic unfavorable (8.91e-4)" "unprognostic (1.74e-1)" "unprognostic (1.92e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.43e-2)" "unprognostic (1.35e-2)" 21.4 16.5 17.2 16.2 17.1 15.1 19.1 20.9 19.9 19.6 16.2 16.1 11.0 16.6 14.8 23.6 18.3 20.9 12.4 17.3 15.5 13.5 15.1 19.0 16.6 16.6 15.1 23.6 18.1 11.8 17.8 18.5 16.3 18.3 14.5 18.0 17.7 10.6 13.9 20.3 13.4 11.8 13.9 20.5 17.7 10.6 15.2 12.3 19.7 4.1 12.0 17.3 16.1 15.9 16.4 24.2 16.5 28.7 19.6 24.9 15.0 22.8 18.1 16.5 25.5 13.4 39.4 31.5 22.6 19.8 16.9 8.5 18.3 17.3 23.7 9.1 15.6 21.5 23.0 25.7 21.9 16.0 13.3 15.9 13.5 13.7 19.9 20.0 12.4 19.7 16.9 11.2 19.9 38.8 30.3 40.5 19.6 38.2 6.5 15.2 10.1 2.2 22.4 55.6 9.0 19.5 35.2 25.7 12.3 17.4 23.9 33.0 20.4 12.0 17.8 17.8 13.4 12.7 25.1 21.8 14.2 22.3 12.0 4.6 10.6 3.1 9.3 6.5 9.4 7.1 4.1 5.5 8.6 6.0 4.4 3.9 4.4 7.9 7.7 1.3 8.8 5.5 17.2 17.1 20.9 19.9 17.3 15.5 16.6 15.1 16.3 13.9 15.2 15.9 25.8 35.3 33.7 122.4 22.2 10.7 16.6 17.8 30.7 11.2 20.1 18.0 19.5 12.8 18.0 12.9 18.8 17.8 15.7 8.8 7.9 8.2 8.5 18.1 20.4 21.4 11.5 12.4 255.4 8.8 11.5 21.7 26.0 21.0 12.6 20.6 10.8 8.3 11.1 13.5 214.4 9.7 10.2 33.1 11.3 7.6 14.6 27.4 8.8 216.4 24.9 8.7 15.5 207.6 141.4 7.1 10.1 14.7 16.6 15.1 6.0 4.9 26.5 12.2 6.6 17.5 16.9 21.7 29.7 27.6 8.7 16.4 15.1 10.9 12.3 18.6 CEBPD "C/EBP-delta, CELF, CRP3, NF-IL6-beta" ENSG00000221869 "CCAAT enhancer binding protein delta" P49716 8 47736913-47738164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1541.7;Basal prostatic cells: 1435.6;Basal squamous epithelial cells: 2487.0;Prostatic glandular cells: 1668.5;Skeletal myocytes: 1386.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 54.9" "Group enriched" "Detected in many" 5 "granulocytes: 54.9;monocytes: 19.9" "Cell line enhanced" "Detected in many" "BEWO: 51.9;HHSteC: 66.8;HSkMC: 66.7;NB-4: 148.7;SiHa: 58.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA067581 Approved Nucleoplasm NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "HPA067581: AB_2685865" "prognostic favorable (2.28e-5)" "unprognostic (1.43e-1)" "unprognostic (2.99e-2)" "unprognostic (1.74e-2)" "unprognostic (2.14e-2)" "unprognostic (6.35e-3)" "unprognostic (1.52e-2)" "unprognostic (2.12e-1)" "unprognostic (6.81e-2)" "unprognostic (5.16e-2)" "unprognostic (5.47e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "unprognostic (4.62e-2)" "unprognostic (3.40e-2)" 251.6 72.0 33.4 62.1 35.2 34.3 168.0 37.2 42.0 99.7 43.9 143.5 26.7 82.8 2.7 85.4 192.0 14.7 136.9 35.8 63.6 106.9 207.8 157.5 8.7 81.5 49.3 265.3 81.9 7.6 117.4 50.0 49.5 151.1 12.1 16.9 89.3 19.4 133.0 106.9 79.6 21.6 46.5 109.7 116.3 14.3 47.4 18.5 103.5 21.6 6.6 168.1 139.9 44.6 9.5 7.4 0.3 0.1 41.5 43.2 51.9 24.1 18.7 6.8 14.4 14.8 14.8 0.1 17.3 6.6 5.8 9.9 1.7 12.9 2.1 0.1 3.9 0.5 6.0 6.3 66.8 4.1 0.0 66.7 33.7 1.6 16.0 4.3 1.4 0.4 4.1 7.3 2.5 2.9 0.1 148.7 2.8 6.2 2.5 0.1 5.1 0.5 20.6 7.8 2.8 1.0 58.7 7.7 6.3 2.6 6.4 33.5 6.2 1.5 3.9 15.6 1.5 0.1 0.1 0.1 7.9 0.1 0.3 2.3 19.9 10.6 2.1 8.4 6.2 0.1 0.3 1.2 7.4 0.6 0.0 0.0 54.9 3.7 3.2 0.2 0.3 2.8 33.4 35.2 37.2 42.0 35.8 63.6 81.5 49.3 49.5 46.5 47.4 44.6 1541.7 102.5 196.3 31.3 14.9 663.5 1435.6 98.7 2487.0 6.0 551.3 617.1 79.2 185.8 76.5 224.3 6.2 189.8 152.8 59.2 217.2 50.7 3.5 287.0 418.9 547.9 23.4 30.3 12.5 77.2 457.9 1377.3 387.3 621.0 5.1 96.4 269.5 157.7 220.3 1.7 2.5 44.3 42.7 520.1 502.0 21.5 435.5 912.6 268.6 29.0 163.5 321.9 150.4 6.0 0.5 53.2 58.4 144.8 34.9 1668.5 127.1 353.4 54.9 17.3 466.8 1386.3 1290.5 3.7 13.9 940.2 817.5 351.9 122.7 85.9 73.2 814.5 PRKDC "DNA-PKC, DNA-PKcs, DNAPK, DNAPKc, DNPK1, HYRC, HYRC1, p350, p460, XRCC7" ENSG00000253729 "Protein kinase, DNA-activated, catalytic subunit" P78527 8 47773111-47960178 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, Ribosome biogenesis" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005167, HPA035174" Supported Enhanced Nucleoplasm NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm "CAB005167: AB_2172845, HPA035174: AB_2674504" "unprognostic (3.14e-2)" "unprognostic (3.02e-3)" "unprognostic (1.56e-2)" "prognostic unfavorable (1.03e-4)" "unprognostic (8.95e-2)" "unprognostic (1.34e-1)" "unprognostic (7.70e-3)" "unprognostic (5.74e-2)" "unprognostic (1.12e-2)" "unprognostic (1.60e-2)" "unprognostic (7.76e-3)" "unprognostic (7.77e-2)" "unprognostic (2.84e-2)" "unprognostic (2.32e-1)" "unprognostic (2.20e-1)" "unprognostic (6.76e-3)" "unprognostic (2.15e-2)" 17.3 16.8 8.6 14.1 10.7 19.2 16.1 9.8 11.9 18.2 10.8 16.2 7.0 20.1 8.0 24.0 18.3 7.4 16.7 10.6 9.3 14.8 14.0 14.8 17.9 10.4 10.0 19.8 18.0 14.0 16.3 10.9 9.8 13.5 11.6 23.8 16.0 9.2 26.4 19.8 17.2 12.1 10.6 18.8 16.6 18.3 9.6 27.8 13.4 15.0 17.1 18.7 17.5 14.3 123.5 103.4 98.4 93.9 59.9 63.0 41.6 51.2 49.9 70.3 68.9 68.0 39.6 117.1 43.1 63.3 52.3 68.5 131.3 70.2 109.3 26.3 81.8 230.2 92.1 83.7 25.8 88.6 46.0 45.9 22.5 111.3 115.3 27.1 73.4 79.5 156.6 48.0 78.8 57.7 125.8 72.3 108.6 85.6 31.2 60.8 77.3 41.2 35.5 104.4 49.2 62.5 158.1 50.6 51.1 60.2 72.6 60.1 86.2 91.5 78.0 73.0 104.2 41.3 56.7 162.8 51.7 97.9 75.6 11.4 8.1 4.1 8.7 6.8 11.0 13.1 10.8 9.2 6.5 16.7 11.2 10.3 7.7 12.8 13.7 15.3 8.3 2.9 8.6 10.7 9.8 11.9 10.6 9.3 10.4 10.0 9.8 10.6 9.6 14.3 73.4 38.5 36.1 56.8 67.9 38.4 48.3 59.7 77.4 103.4 63.1 64.0 82.1 22.8 44.1 42.3 125.1 61.1 81.9 17.5 17.6 41.9 29.0 66.0 166.5 59.7 25.8 147.6 85.5 36.0 60.6 73.2 55.0 72.6 45.6 105.1 32.5 41.2 35.9 104.3 77.1 31.2 38.7 45.5 20.1 15.5 56.8 54.6 19.6 61.8 63.6 73.1 57.7 82.0 76.0 34.9 16.6 69.6 69.3 57.1 13.2 23.5 50.1 111.6 52.6 91.2 69.3 100.7 106.3 85.3 40.6 33.0 71.0 143.2 55.2 36.4 MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.2" "Cell type enhanced" "Detected in many" "Early spermatids: 153.2;Erythroid cells: 60.8;Late spermatids: 77.9;Spermatocytes: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 140000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB004497: AB_627916, HPA004873: AB_1079337, HPA031052: AB_2673712" "unprognostic (4.55e-2)" "unprognostic (3.16e-3)" "prognostic favorable (2.19e-4)" "prognostic unfavorable (2.84e-5)" "unprognostic (7.71e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.15e-4)" "unprognostic (2.65e-2)" "prognostic unfavorable (2.38e-4)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.70e-2)" "unprognostic (1.40e-1)" 6.5 8.8 4.8 21.7 4.8 63.2 16.0 5.7 5.2 7.7 1.8 17.7 13.3 6.9 4.6 22.4 9.7 5.6 14.5 5.2 3.5 8.2 9.2 6.3 38.7 3.6 4.2 7.1 5.5 7.7 4.1 18.3 3.9 5.6 21.3 12.3 8.8 4.9 13.4 24.2 16.7 9.2 4.2 8.1 10.6 41.6 4.8 47.0 6.5 15.8 41.8 11.8 10.9 5.2 184.0 139.6 188.1 83.2 20.7 36.6 102.8 122.6 99.8 178.5 190.3 156.6 181.1 229.8 70.3 72.1 119.2 143.2 278.7 128.2 199.8 64.2 190.4 371.8 133.3 169.2 5.4 189.7 82.0 20.3 24.1 147.8 54.3 28.6 72.0 136.8 216.2 167.0 129.9 155.6 435.5 141.5 241.2 246.5 54.2 266.6 159.6 139.2 64.9 168.1 209.0 97.8 325.6 133.6 46.3 117.7 154.9 110.5 45.1 138.1 125.4 144.5 131.9 54.7 104.6 347.2 114.8 185.7 131.5 2.3 1.8 1.1 4.0 3.1 2.0 3.9 3.8 5.4 3.9 1.6 3.3 2.7 0.1 4.1 3.5 1.5 10.2 3.6 4.8 4.8 5.7 5.2 5.2 3.5 3.6 4.2 3.9 4.2 4.8 5.2 3.3 0.0 6.3 3.3 6.5 21.7 11.1 9.0 13.6 12.2 9.0 7.7 25.1 1.5 8.4 5.5 10.4 36.7 5.8 12.1 3.9 8.0 153.2 11.0 7.9 6.7 6.7 60.8 5.0 6.0 40.2 10.6 11.2 13.4 1.3 24.9 2.2 3.2 12.3 16.8 5.7 13.9 4.1 2.9 6.5 77.9 5.3 7.9 3.6 1.9 2.4 7.0 3.1 4.0 2.9 4.5 4.8 3.0 22.3 7.7 5.6 3.0 13.1 16.7 0.0 9.5 11.4 65.8 39.9 19.1 19.0 29.8 9.0 11.7 26.2 9.7 UBE2V2 "DDVit-1, DDVIT1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2" ENSG00000169139 "Ubiquitin conjugating enzyme E2 V2" Q15819 8 48008415-48064708 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052535, HPA053186" Supported Nucleoplasm NA NA 800000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA052535: AB_2681863, HPA053186: AB_2682073" "unprognostic (3.50e-3)" "unprognostic (3.27e-1)" "unprognostic (1.53e-1)" "unprognostic (3.07e-2)" "unprognostic (1.69e-1)" "unprognostic (5.83e-2)" "unprognostic (2.94e-3)" "unprognostic (1.21e-2)" "unprognostic (1.65e-3)" "unprognostic (4.97e-2)" "unprognostic (1.77e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (4.96e-6)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (2.45e-1)" "unprognostic (9.62e-2)" 36.6 42.9 40.0 32.1 44.0 23.0 35.5 38.3 50.3 28.2 33.5 43.7 35.1 32.9 26.7 49.0 26.2 27.5 25.3 45.7 47.0 35.8 60.8 23.3 39.2 44.4 42.2 24.4 21.4 36.9 36.0 31.4 45.2 34.0 36.1 52.1 23.2 30.8 56.3 25.4 33.0 38.3 39.6 23.7 32.8 34.3 46.4 52.1 37.2 56.0 39.7 41.7 31.7 38.6 112.7 63.9 140.0 78.0 75.4 83.6 49.4 114.8 80.1 113.8 99.2 80.9 85.3 136.9 65.7 110.5 97.4 66.1 128.6 107.8 152.1 47.2 89.8 123.6 74.4 68.8 94.0 68.2 35.7 79.5 109.9 91.7 145.6 86.1 97.6 115.8 154.0 83.0 145.3 85.7 218.3 131.6 130.3 166.7 42.2 108.3 61.8 67.6 122.7 90.0 152.9 99.4 96.7 85.1 107.5 103.8 143.0 89.7 54.1 95.8 87.8 86.6 108.7 82.3 151.5 175.8 124.3 118.7 104.0 73.9 70.5 74.4 58.9 84.9 71.6 77.4 72.6 72.8 87.2 76.1 72.2 81.7 45.1 110.6 85.0 73.3 104.6 94.2 40.0 44.0 38.3 50.3 45.7 47.0 44.4 42.2 45.2 39.6 46.4 38.6 52.4 48.1 34.7 20.2 53.1 45.2 75.5 172.5 36.5 87.1 40.9 51.8 58.9 35.8 89.0 51.5 16.7 93.3 39.9 29.9 129.1 81.9 51.6 46.7 58.3 45.4 32.3 57.0 41.6 88.3 149.6 67.9 30.5 36.9 50.8 55.5 32.2 50.8 90.4 80.8 38.1 49.2 109.9 35.4 53.1 34.6 56.2 51.6 37.4 20.6 76.0 110.8 56.7 21.1 28.4 83.6 56.0 73.4 46.7 95.9 51.9 130.2 71.4 65.2 59.2 48.3 122.1 134.7 82.2 46.8 57.1 149.7 47.2 76.2 59.3 75.0 EFCAB1 FLJ11767 ENSG00000034239 "EF-hand calcium binding domain 1" Q9HAE3 8 48710789-48735311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 91.6;testis: 37.5" "Group enriched" "Detected in many" 19 "Early spermatids: 538.8;Endometrial ciliated cells: 159.1;Late spermatids: 552.0;Respiratory ciliated cells: 310.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 6.5;ASC diff: 2.6;ASC TERT1: 6.2;CAPAN-2: 3.1;hTEC/SVTERT24-B: 2.6;SCLC-21H: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023527, HPA069955" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Plasma membrane" "HPA023527: AB_2231065, HPA069955: AB_2686220" "unprognostic (5.29e-3)" "unprognostic (7.39e-3)" "unprognostic (1.05e-1)" "unprognostic (2.67e-3)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (9.81e-2)" "unprognostic (1.62e-1)" "unprognostic (2.52e-2)" "unprognostic (1.85e-1)" "unprognostic (5.94e-3)" "unprognostic (7.81e-2)" "unprognostic (4.87e-3)" "unprognostic (4.81e-2)" "unprognostic (1.99e-1)" "unprognostic (2.51e-1)" "unprognostic (3.47e-3)" 0.3 1.5 3.1 0.1 4.7 0.7 3.0 1.9 2.5 11.4 22.4 0.5 0.6 12.4 2.5 0.7 91.6 0.6 0.2 3.7 4.9 0.5 0.7 10.6 0.1 13.5 12.1 19.3 3.2 0.0 3.1 0.5 7.0 5.4 0.4 0.0 2.0 5.9 0.0 4.7 1.0 2.9 9.1 0.3 0.6 37.5 5.7 0.4 0.1 0.2 0.2 2.3 3.4 8.5 6.5 0.0 0.8 0.0 2.6 6.2 0.0 0.1 0.6 0.0 0.2 0.0 3.1 0.0 0.0 0.1 0.0 1.7 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.1 0.2 2.6 1.1 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.5 4.9 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.1 0.0 1.2 0.3 0.0 0.0 0.1 0.0 3.1 4.7 1.9 2.5 3.7 4.9 13.5 12.1 7.0 9.1 5.7 8.5 0.4 0.0 5.9 0.0 0.0 6.8 9.7 14.7 4.0 0.0 0.4 9.1 0.4 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.0 0.3 538.8 159.1 4.7 1.2 0.0 0.0 0.7 1.5 0.1 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 10.2 0.0 0.3 552.0 4.7 0.8 1.8 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 5.7 0.0 3.4 0.0 0.3 310.7 0.0 0.0 0.7 6.2 16.9 4.5 0.1 1.8 0.3 0.4 3.9 0.0 2.5 SNAI2 "SLUG, SLUGH, SLUGH1, SNAIL2" ENSG00000019549 "Snail family transcriptional repressor 2" O43623 8 48917598-48921740 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Deafness, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 162.8;Basal prostatic cells: 119.4;Basal respiratory cells: 98.9;Endometrial stromal cells: 129.2;Melanocytes: 87.2;Suprabasal keratinocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 243.2;ASC TERT1: 247.8;HSkMC: 181.3;hTERT-HME1: 180.3;LHCN-M2: 228.8;U-138 MG: 206.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB011671 Supported Approved Nucleoplasm NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "CAB011671: AB_777968" "unprognostic (3.52e-2)" "unprognostic (3.95e-1)" "unprognostic (1.55e-1)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (1.74e-2)" "unprognostic (1.79e-1)" "unprognostic (1.04e-2)" "unprognostic (4.24e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.83e-4)" "unprognostic (2.38e-1)" "prognostic unfavorable (4.69e-8)" "unprognostic (1.65e-3)" "unprognostic (3.76e-2)" "unprognostic (1.87e-1)" "prognostic unfavorable (7.16e-4)" 28.2 10.6 0.5 15.7 0.8 0.4 22.9 3.6 1.4 51.1 1.7 11.6 4.3 43.0 11.3 15.8 34.4 21.8 15.0 0.8 0.5 12.4 9.6 11.1 8.1 0.8 0.5 40.8 8.0 3.6 2.3 16.2 0.6 19.8 7.6 0.1 16.8 23.2 4.6 39.8 11.5 27.5 0.4 14.2 9.4 3.7 0.6 6.9 9.5 7.7 7.9 37.8 51.3 0.5 17.7 0.6 38.5 0.4 243.2 247.8 0.1 38.6 69.0 38.1 52.3 0.0 17.4 0.0 0.0 50.1 56.7 28.9 0.4 111.8 40.2 0.0 0.8 0.0 7.2 0.1 88.5 0.1 0.1 181.3 116.8 31.9 180.3 5.4 1.3 0.0 0.0 18.5 228.8 0.3 0.0 0.1 2.3 0.0 34.7 0.0 122.2 0.2 0.1 6.8 5.1 3.8 3.3 0.1 69.2 18.9 0.2 0.2 10.6 206.6 7.4 36.6 20.9 0.0 0.1 4.2 74.9 0.0 78.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 3.6 1.4 0.8 0.5 0.8 0.5 0.6 0.4 0.6 0.5 11.7 0.0 0.0 0.0 0.1 162.8 119.4 98.9 60.9 1.9 2.1 22.0 1.2 1.5 14.0 0.0 0.0 1.7 0.3 0.0 0.0 3.0 0.6 5.2 129.2 19.5 0.0 0.0 0.6 2.3 0.5 69.9 0.0 4.8 0.0 0.0 40.0 6.8 1.7 0.0 0.5 0.0 10.2 0.8 30.7 1.7 73.7 1.9 87.2 0.0 0.0 0.0 0.0 1.0 0.0 6.1 0.0 67.4 1.4 18.4 0.0 0.0 2.4 0.2 52.6 24.7 59.2 0.2 0.4 32.3 147.9 2.2 2.3 21.8 0.0 25.0 PPDPFL C8orf22 ENSG00000168333 "Pancreatic progenitor cell differentiation and proliferation factor like" Q8WWR9 8 49054311-49076093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 948.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "glioma: 0.7;renal cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "HEL: 1.3" HPA060329 Uncertain NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 50: Fibroblasts - ECM organization" "HPA060329: AB_2684255" "unprognostic (6.33e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.06e-10)" 2.6 0.1 0.2 0.0 0.6 0.0 1.1 0.6 0.5 0.0 0.2 0.2 0.0 0.0 0.0 2.4 0.1 0.0 1.6 0.3 1.4 0.0 0.1 0.1 0.0 1.0 0.2 0.1 0.1 0.0 0.3 0.0 1.1 2.3 0.0 0.3 9.8 0.2 948.1 1.7 0.2 0.0 0.5 0.0 0.1 0.2 0.4 0.0 0.3 112.8 0.0 0.3 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.6 0.5 0.3 1.4 1.0 0.2 1.1 0.5 0.4 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SNTG1 "G1SYN, SYN4" ENSG00000147481 "Syntrophin gamma 1" Q9NSN8 8 49909789-50796692 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;lymphoid tissue: 2.8" "Group enriched" "Detected in some" 25 "Excitatory neurons: 1498.8;Inhibitory neurons: 1490.6;Oligodendrocyte precursor cells: 1948.8" "Cancer enriched" "Detected in single" 5 "glioma: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "RH-30: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072282 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA072282: AB_2686506" "unprognostic (4.60e-2)" "unprognostic (1.72e-2)" "unprognostic (2.47e-1)" "unprognostic (1.05e-2)" "unprognostic (6.94e-2)" "unprognostic (2.03e-1)" "unprognostic (1.16e-3)" 0.0 0.4 2.3 0.0 5.4 0.4 0.0 0.8 10.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.0 5.5 2.7 0.3 0.5 0.0 0.1 0.0 2.4 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.1 0.0 0.2 0.0 0.1 0.0 2.8 0.1 0.7 5.3 0.1 0.1 0.0 0.0 0.3 0.0 3.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.1 0.6 0.0 0.1 0.4 0.0 0.0 0.0 0.0 5.1 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 2.3 5.4 0.8 10.5 5.5 2.7 0.0 2.4 0.0 0.0 5.3 3.7 0.0 0.0 0.5 27.7 0.0 0.0 0.0 0.0 0.0 37.0 0.0 0.0 0.4 0.0 0.6 1.8 0.0 0.0 0.2 0.0 0.0 0.0 21.5 0.1 0.0 0.1 0.0 0.0 1498.8 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 1.7 1490.6 0.0 0.0 0.0 0.0 56.2 0.6 0.1 0.0 64.6 0.0 0.4 0.0 1948.8 18.3 0.3 0.0 0.4 0.0 0.0 0.0 0.9 0.0 1.0 0.0 0.0 0.1 7.8 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 PXDNL "FLJ25471, PMR1" ENSG00000147485 "Peroxidasin like" A1KZ92 8 51319577-51809445 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Endonuclease, Hydrolase, Nuclease, Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "heart muscle: 45.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 42.2;Early spermatids: 43.8;Excitatory neurons: 25.2;Inhibitory neurons: 68.8;Microglial cells: 16.9;Muller glia cells: 18.6;Spermatocytes: 24.2" "Group enriched" "Detected in some" 4 "breast cancer: 1.7;glioma: 0.7;renal cancer: 0.8;testis cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 7.7;Daudi: 5.9;SH-SY5Y: 6.1" HPA007919 Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "HPA007919: AB_1855966" "prognostic unfavorable (3.27e-5)" "unprognostic (4.59e-4)" "unprognostic (5.57e-3)" "unprognostic (2.83e-3)" "unprognostic (2.71e-1)" "unprognostic (5.14e-2)" "unprognostic (1.18e-1)" "unprognostic (7.18e-3)" "unprognostic (1.85e-1)" "unprognostic (1.15e-1)" "unprognostic (7.07e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-4)" "unprognostic (2.28e-2)" "unprognostic (3.35e-2)" "unprognostic (2.42e-2)" "unprognostic (2.97e-4)" 1.6 0.1 0.2 0.2 0.1 0.0 0.2 0.2 0.6 0.1 0.0 0.1 0.0 0.1 9.4 0.2 0.0 0.1 45.3 0.2 0.3 1.6 0.0 0.2 0.3 0.5 0.6 0.1 0.0 0.2 0.0 0.0 0.8 0.2 0.1 2.9 0.3 0.0 1.4 0.2 0.2 0.0 0.1 0.4 0.0 5.0 0.2 0.5 0.3 2.1 0.5 0.0 0.0 0.4 0.5 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.6 0.2 0.3 0.5 0.6 0.8 0.1 0.2 0.4 0.3 0.0 0.0 10.7 0.0 0.1 0.1 0.0 0.0 1.2 3.7 0.1 42.2 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.9 0.0 43.8 0.0 0.0 0.3 0.0 0.0 25.2 0.0 0.0 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 68.8 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 16.9 0.0 18.6 0.0 14.1 14.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.2 0.8 24.2 1.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA025696: AB_1855077, HPA061444: AB_2684519" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.73e-3)" "unprognostic (2.58e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (8.38e-2)" "unprognostic (3.73e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (3.11e-3)" "unprognostic (3.11e-3)" 36.5 35.2 18.2 23.3 20.2 16.8 38.2 25.2 21.9 33.8 23.2 38.8 25.9 35.3 47.5 28.0 30.8 29.0 35.5 16.4 19.9 38.3 30.4 28.3 28.8 19.1 19.2 42.6 73.9 77.9 25.5 26.3 19.9 36.1 25.8 25.4 57.6 32.0 83.4 33.5 26.8 28.3 18.9 46.3 29.5 14.9 18.9 35.1 53.3 67.1 27.3 32.6 31.0 21.6 11.7 5.7 24.3 5.4 34.1 28.4 14.0 13.4 22.8 5.5 9.0 3.1 23.6 12.0 18.0 17.3 8.4 27.2 4.7 15.8 9.3 11.9 8.5 12.6 11.7 8.3 43.9 5.2 12.4 30.4 31.7 6.9 17.4 35.8 24.4 16.0 9.5 36.0 12.0 4.2 24.5 13.7 8.9 16.7 3.0 8.0 4.5 13.8 24.7 21.7 16.2 15.0 10.9 14.8 17.1 18.5 14.2 7.6 22.2 6.8 5.9 8.8 5.2 21.6 15.6 3.9 16.4 11.4 7.0 18.7 8.4 23.2 8.6 11.0 10.4 13.1 11.5 9.4 8.1 13.0 13.5 12.4 29.4 21.6 12.7 14.7 13.2 9.1 18.2 20.2 25.2 21.9 16.4 19.9 19.1 19.2 19.9 18.9 18.9 21.6 98.4 115.4 68.1 78.7 78.1 54.0 66.0 49.7 58.6 80.7 66.7 61.0 92.7 48.6 52.0 84.6 10.4 38.1 80.7 28.7 64.6 32.9 4.7 66.6 63.9 79.3 46.7 51.4 144.7 39.8 37.2 79.2 45.9 92.2 53.0 107.2 76.4 37.1 25.1 58.9 159.7 39.0 61.1 51.8 56.8 10.4 104.1 62.7 71.2 144.3 52.5 120.8 55.6 106.1 122.3 43.8 32.2 120.0 101.8 98.0 45.5 92.8 56.7 24.0 39.5 73.2 68.2 16.4 24.2 38.3 59.2 68.5 62.1 87.6 30.9 94.6 ST18 "KIAA0535, NZF-3, NZF3, ZC2H2C3, ZC2HC10, ZNF387" ENSG00000147488 "ST18 C2H2C-type zinc finger transcription factor" O60284 8 52110839-52460959 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 82.1" "Cell type enriched" "Detected in some" 39 "Oligodendrocytes: 4055.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.7;SCLC-21H: 9.6;U-87 MG: 1.5" "Region enhanced" "Detected in all" "cerebellum: 40.2" "Low region specificity" "Detected in all" HPA044919 Uncertain NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "HPA044919: AB_10959756" "unprognostic (3.66e-1)" "unprognostic (4.34e-2)" "unprognostic (7.47e-2)" "unprognostic (2.04e-2)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (1.22e-1)" "unprognostic (7.11e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-3)" "unprognostic (2.82e-1)" "unprognostic (2.53e-5)" "unprognostic (3.29e-1)" "unprognostic (1.35e-1)" "unprognostic (9.34e-2)" "unprognostic (9.84e-3)" 0.0 0.9 18.4 0.1 48.6 0.0 0.0 44.1 24.1 0.0 1.7 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.0 18.0 29.0 0.3 0.1 0.1 0.0 47.8 37.4 0.0 1.9 0.0 4.4 0.1 43.5 0.1 0.3 8.5 0.0 0.0 0.0 0.0 0.5 0.0 22.3 0.0 1.5 0.3 35.7 0.1 0.0 0.0 0.1 0.0 0.0 82.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 48.6 44.1 24.1 18.0 29.0 47.8 37.4 43.5 22.3 35.7 82.1 0.0 0.0 0.0 4.9 0.6 0.1 0.1 0.0 0.0 101.5 0.0 0.0 1.1 4.3 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 7.4 0.0 0.0 0.2 49.6 1.3 3.4 0.0 0.4 0.2 5.1 0.0 0.0 0.0 0.0 0.2 1.3 1.7 8.5 0.8 10.2 1.6 11.0 1.7 0.0 3.4 0.0 0.0 0.7 2.4 0.0 13.0 4055.3 0.3 0.0 0.0 0.1 0.3 0.1 0.8 0.0 4.5 0.0 0.0 0.1 0.3 0.3 0.0 0.3 0.1 0.1 0.0 0.3 0.0 ALKAL1 "AUGB, FAM150A, UNQ9433" ENSG00000196711 "ALK and LTK ligand 1" Q6UXT8 8 52534037-52565430 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.4;thyroid gland: 2.4" "Cell type enriched" "Detected in some" 4 "Distal tubular cells: 5.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CAPAN-2: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027368 Uncertain "Secreted - unknown location" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 30: Mammary glandular cells - Lactation" "HPA027368: AB_10602317" "unprognostic (1.18e-1)" "unprognostic (1.13e-4)" "unprognostic (9.47e-2)" "unprognostic (9.64e-2)" "unprognostic (1.52e-1)" "unprognostic (6.60e-2)" "unprognostic (1.70e-4)" "unprognostic (4.48e-2)" "unprognostic (1.71e-1)" "unprognostic (1.34e-1)" "unprognostic (9.58e-3)" 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 1.2 0.0 1.1 0.6 0.0 0.0 0.0 0.2 2.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.5 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.5 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.7 0.2 0.0 0.4 0.1 0.1 0.0 2.4 0.0 0.0 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.5 0.1 0.5 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 5.9 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RB1CC1 "ATG17, Cc1, DRAGOU14, FIP200, KIAA0203, PPP1R131" ENSG00000023287 "RB1 inducible coiled-coil 1" Q8TDY2 8 52622458-52745843 "Predicted intracellular proteins" "Autophagy, Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024391, HPA053049" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nuclear membrane" "HPA024391: AB_2671554, HPA053049: AB_2682025" "unprognostic (1.58e-2)" "unprognostic (7.51e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (3.22e-1)" "unprognostic (4.21e-2)" "unprognostic (7.39e-2)" "unprognostic (1.38e-2)" "unprognostic (9.34e-2)" "unprognostic (1.21e-1)" "unprognostic (8.77e-3)" "unprognostic (2.07e-1)" "unprognostic (9.56e-3)" "unprognostic (7.67e-2)" "unprognostic (4.41e-1)" "unprognostic (8.00e-2)" "unprognostic (2.42e-1)" 17.6 15.0 37.2 11.8 30.4 52.3 17.0 26.5 40.2 15.2 16.4 13.7 12.9 17.4 13.0 16.9 12.1 13.8 24.1 27.2 23.9 17.1 21.5 14.9 13.3 29.9 25.6 20.1 16.8 22.2 8.0 15.5 24.1 15.5 11.3 20.3 16.2 12.2 38.9 15.0 14.2 15.0 23.0 14.3 14.5 34.7 33.1 22.2 17.7 32.1 12.9 14.3 11.1 43.5 23.8 20.8 25.2 22.1 27.4 31.0 14.4 17.7 36.1 18.4 22.8 14.6 26.3 17.4 29.0 26.2 46.4 31.0 31.4 16.5 34.5 13.1 27.4 29.7 20.8 20.2 33.7 10.7 16.0 29.1 33.4 18.3 49.6 38.2 25.2 26.8 35.8 27.4 22.6 15.6 27.2 15.7 24.9 22.4 10.3 13.7 12.1 17.7 16.9 18.5 24.0 25.0 18.4 20.9 39.8 29.3 23.8 19.3 29.9 17.5 24.2 27.8 15.7 26.8 24.8 17.0 27.6 18.2 20.0 47.9 12.9 24.6 11.6 12.2 11.8 12.3 9.7 11.9 12.6 9.5 11.9 11.0 40.3 14.2 17.1 6.3 14.1 11.9 37.2 30.4 26.5 40.2 27.2 23.9 29.9 25.6 24.1 23.0 33.1 43.5 83.8 195.5 121.7 73.8 66.3 88.3 60.2 32.0 51.2 82.0 45.5 39.5 163.8 20.0 57.4 18.4 68.8 27.0 74.2 45.4 9.8 52.4 61.9 103.6 112.7 66.0 44.2 117.7 104.0 49.3 26.3 78.2 36.2 143.5 25.9 78.1 36.8 44.5 23.6 87.5 123.2 31.9 30.5 44.5 41.4 49.8 77.3 60.5 42.7 76.8 67.6 33.0 64.9 106.1 104.2 63.5 43.3 73.4 86.1 99.0 47.2 27.0 115.3 57.3 46.0 132.2 76.9 238.8 132.7 59.4 91.9 60.5 66.2 68.6 27.7 88.2 NPBWR1 GPR7 ENSG00000288611 "Neuropeptides B and W receptor 1" P48145 8 52939182-52943734 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.6;liver: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.2;SiHa: 1.1;TIME: 1.0" "Low region specificity" "Detected in some" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 20: HeLa - Mitochondria" 0.0 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.9 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.3 1.6 0.0 2.1 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.9 0.0 0.9 0.3 1.6 0.9 0.3 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 14.5" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 4.5;Excitatory neurons: 6.7;Extravillous trophoblasts: 8.0;Glandular and luminal cells: 9.8;Inhibitory neurons: 10.1;Leydig cells: 4.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.1 0.1 7.3 0.0 14.5 0.0 0.0 1.3 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 5.4 0.0 0.0 0.1 0.0 5.8 1.7 0.0 0.0 0.0 0.0 0.2 5.1 1.6 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 6.9 0.1 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 14.5 1.3 8.3 3.9 5.4 5.8 1.7 5.1 0.3 6.9 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 4.5 0.6 0.1 0.0 0.0 6.7 0.0 8.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 RGS20 "RGSZ1, ZGAP1" ENSG00000147509 "Regulator of G protein signaling 20" O76081 8 53851795-53959303 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.5;choroid plexus: 3.9;retina: 4.9" "Cell type enriched" "Detected in some" 7 "Astrocytes: 238.6" "Cancer enhanced" "Detected in many" "melanoma: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 27.7;SK-MEL-30: 30.4;U-87 MG: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070193 Enhanced NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA070193: AB_2732150" "unprognostic (2.14e-2)" "unprognostic (2.87e-2)" "unprognostic (1.89e-2)" "unprognostic (1.95e-1)" "unprognostic (1.48e-1)" "unprognostic (4.97e-2)" "unprognostic (1.91e-5)" "unprognostic (5.03e-5)" "unprognostic (2.15e-1)" "unprognostic (1.57e-2)" "unprognostic (8.86e-3)" "unprognostic (5.28e-2)" "unprognostic (2.75e-8)" "unprognostic (3.71e-3)" "unprognostic (9.78e-3)" "unprognostic (8.32e-2)" "unprognostic (1.69e-2)" 0.1 0.0 8.5 0.0 12.5 0.0 0.1 6.6 11.3 0.8 3.9 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 8.2 6.3 0.0 0.0 0.0 0.0 5.4 5.1 0.0 0.0 0.0 0.1 1.2 5.0 0.0 0.0 4.9 0.3 0.0 0.0 2.6 0.0 0.0 5.4 0.0 0.0 0.1 7.3 0.0 1.3 0.0 0.2 0.0 1.0 7.8 14.6 10.1 19.3 0.3 0.7 2.3 0.0 7.9 4.6 6.7 4.0 0.0 8.8 0.0 0.4 2.2 27.7 10.6 0.4 12.8 4.5 0.0 1.5 2.5 1.5 1.7 3.1 0.0 0.9 0.4 8.1 5.5 16.0 14.9 2.6 0.0 0.7 0.0 11.3 0.0 0.0 0.4 0.3 2.1 4.0 0.0 0.6 0.0 12.9 0.9 12.0 1.1 0.6 0.0 30.4 2.8 0.0 0.1 8.5 1.7 0.0 14.4 5.9 2.4 0.0 0.0 28.9 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 12.5 6.6 11.3 8.2 6.3 5.4 5.1 5.0 5.4 7.3 7.8 0.2 0.0 0.0 238.6 0.1 2.0 0.5 10.9 0.6 1.3 0.2 0.0 0.8 0.0 2.7 0.0 31.3 0.7 0.0 0.1 0.0 0.6 0.5 4.2 1.0 0.2 0.0 0.0 3.2 0.4 0.8 0.6 0.0 5.5 0.0 0.0 0.0 0.0 0.2 0.0 6.0 0.0 4.1 0.0 0.0 0.0 0.3 0.1 5.4 9.4 0.0 5.5 0.0 5.0 0.7 1.3 0.0 0.0 0.0 5.1 0.0 0.0 2.6 13.7 0.0 0.1 0.5 0.1 1.3 0.4 0.4 0.7 0.1 0.0 0.0 0.6 TCEA1 "GTF2S, SII, TCEA, TF2S, TFIIS" ENSG00000187735 "Transcription elongation factor A1" P23193 8 53966552-54022456 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043786 Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA043786: AB_10959468" "unprognostic (5.35e-2)" "unprognostic (9.90e-2)" "unprognostic (2.39e-1)" "unprognostic (2.11e-3)" "unprognostic (3.34e-2)" "unprognostic (1.17e-1)" "unprognostic (3.72e-2)" "unprognostic (1.77e-1)" "unprognostic (4.14e-2)" "unprognostic (1.00e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.80e-3)" "unprognostic (1.10e-1)" "unprognostic (1.13e-1)" "unprognostic (3.05e-2)" 52.7 46.0 44.1 56.5 47.5 81.2 62.2 44.7 58.3 55.3 42.5 49.7 47.1 55.6 45.8 53.9 52.4 42.6 35.9 42.0 46.0 59.8 90.4 46.7 98.3 47.2 44.6 61.9 68.4 80.0 28.2 49.3 47.0 59.0 50.7 49.0 56.5 54.2 42.0 49.8 46.9 52.4 47.5 49.5 52.2 36.8 44.2 72.4 124.2 41.7 112.6 54.6 41.4 55.1 161.3 157.9 138.1 145.7 99.3 121.8 100.9 122.1 147.3 143.5 160.2 91.4 131.0 392.5 136.9 147.0 152.5 120.9 182.3 116.6 212.9 225.0 88.5 293.6 71.5 139.5 309.7 116.8 122.7 88.5 308.1 137.4 606.2 121.3 128.2 132.9 191.1 334.0 135.5 75.6 245.8 83.3 229.1 265.0 47.1 185.1 48.2 72.5 204.0 107.0 129.9 95.5 101.9 91.0 356.3 132.2 129.6 132.6 110.6 106.1 96.3 120.6 114.5 201.1 134.4 260.9 184.9 133.2 152.1 82.3 64.1 78.7 103.9 63.1 98.3 213.8 107.0 96.7 81.8 174.1 93.9 99.3 23.1 97.5 60.6 116.7 153.0 73.5 44.1 47.5 44.7 58.3 42.0 46.0 47.2 44.6 47.0 47.5 44.2 55.1 94.7 89.8 106.2 24.2 253.2 135.5 128.3 98.9 257.2 77.0 129.2 124.3 23.9 82.9 109.4 99.3 89.6 115.5 143.8 61.0 168.3 121.0 86.4 126.9 145.4 92.5 87.2 330.7 17.7 109.9 125.1 118.8 111.6 124.4 98.7 75.7 66.4 160.7 87.7 57.2 20.1 96.6 118.0 89.5 134.2 191.0 134.8 124.2 117.4 17.8 132.5 166.0 170.0 22.1 29.7 121.1 71.6 132.8 341.1 146.0 72.2 207.6 110.6 104.5 78.9 102.6 130.4 94.9 103.1 237.2 150.6 112.1 154.8 108.5 88.1 148.6 LYPLA1 "APT-1, LPL1" ENSG00000120992 "Lysophospholipase 1" O75608 8 54046367-54102017 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 787.7;Late spermatids: 796.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050941, HPA063151" Enhanced Approved Nucleoplasm,Cytosol NA NA 330000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "HPA050941: AB_2681284, HPA063151: " "unprognostic (2.62e-2)" "unprognostic (1.28e-2)" "unprognostic (3.25e-3)" "unprognostic (9.42e-2)" "unprognostic (9.48e-2)" "unprognostic (3.56e-1)" "unprognostic (9.58e-2)" "unprognostic (2.05e-2)" "unprognostic (6.52e-3)" "unprognostic (3.76e-2)" "prognostic unfavorable (2.34e-4)" "unprognostic (2.58e-1)" "unprognostic (2.15e-1)" "unprognostic (1.01e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (2.56e-3)" 25.8 30.3 8.8 31.8 7.6 43.6 45.0 10.5 12.7 23.3 14.7 42.6 44.4 19.7 16.1 55.0 22.9 25.9 40.9 7.9 10.8 63.4 83.5 25.9 49.0 9.9 9.5 11.7 23.8 40.8 8.8 50.4 9.1 35.0 42.1 45.9 35.5 15.0 54.5 41.4 42.8 24.3 9.7 30.2 35.4 65.1 10.3 28.8 28.4 70.7 52.0 63.1 27.5 10.0 124.0 69.3 85.9 78.7 31.0 49.4 109.8 71.7 41.6 65.0 61.1 53.2 116.7 214.8 83.6 47.2 70.5 80.7 122.8 119.9 89.8 78.9 70.0 148.8 37.9 80.0 50.8 91.4 196.1 44.6 103.8 50.8 114.0 55.6 171.6 91.6 154.5 63.4 91.3 32.7 141.1 69.9 129.3 206.3 31.5 85.3 45.2 99.3 100.2 163.6 45.2 77.6 50.1 93.6 113.4 81.0 137.0 81.7 83.4 39.0 56.9 68.7 67.8 89.3 143.8 194.0 52.9 97.1 78.7 93.7 80.7 111.1 44.8 79.6 44.6 73.0 42.2 43.5 92.3 64.4 42.1 41.1 49.3 69.6 108.2 59.7 75.5 98.3 8.8 7.6 10.5 12.7 7.9 10.8 9.9 9.5 9.1 9.7 10.3 10.0 60.4 28.9 53.3 19.9 83.8 61.7 94.8 96.6 82.6 34.9 103.8 64.0 70.8 57.2 71.8 62.5 52.1 199.7 74.5 70.4 303.3 82.8 787.7 86.6 34.7 69.3 57.5 50.0 30.0 89.0 318.3 36.4 74.9 96.3 49.5 31.5 81.4 120.1 121.0 18.5 43.7 77.3 99.7 108.4 83.3 796.2 28.3 82.6 74.7 25.3 102.1 36.9 69.0 20.6 9.8 127.4 63.7 23.0 104.5 171.0 91.6 194.3 62.9 70.3 46.0 24.5 43.1 92.1 239.1 118.2 81.1 334.2 57.0 94.0 90.2 229.7 MRPL15 "HSPC145, L15mt, MRP-L15, MRP-L7, RPML7" ENSG00000137547 "Mitochondrial ribosomal protein L15" Q9P015 8 54135241-54148514 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 291.2;tongue: 279.4" "Cell type enhanced" "Detected in all" "Distal tubular cells: 248.4;Syncytiotrophoblasts: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044425 Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA044425: AB_10969629" "unprognostic (5.67e-3)" "unprognostic (8.89e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (9.30e-2)" "unprognostic (1.90e-2)" "unprognostic (2.57e-2)" "unprognostic (3.10e-3)" "unprognostic (1.39e-1)" "unprognostic (3.39e-2)" "unprognostic (1.94e-3)" "unprognostic (1.57e-2)" "unprognostic (2.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.06e-2)" 42.5 34.4 33.2 36.4 34.1 25.1 49.3 37.0 50.5 32.6 38.7 70.8 58.6 28.6 27.7 48.8 35.6 29.0 169.6 33.5 38.3 83.8 89.2 26.5 42.9 36.6 35.7 30.5 29.2 83.4 18.6 49.6 35.8 27.5 67.5 63.1 41.4 29.0 291.2 38.5 50.6 45.4 33.8 27.3 38.4 14.7 38.3 38.1 35.2 279.4 57.4 64.1 26.3 33.0 164.1 118.9 98.0 122.6 76.1 110.5 125.8 128.4 93.0 173.3 150.2 134.1 197.1 253.9 170.3 112.1 164.4 161.5 206.2 165.5 190.4 109.9 109.5 165.8 62.4 168.5 114.5 92.0 168.9 103.3 167.4 159.5 165.6 74.7 366.7 89.4 208.2 80.8 251.3 156.1 262.4 177.3 206.2 313.9 60.8 169.5 63.6 136.3 210.8 147.1 56.5 83.7 66.8 204.0 167.0 97.4 195.2 96.6 129.6 95.8 111.7 139.5 151.5 94.6 128.4 207.1 88.8 137.8 153.4 40.1 93.8 27.3 50.7 123.4 63.8 100.6 64.8 68.4 141.1 76.6 59.0 56.9 3.3 54.0 115.7 88.9 79.8 85.8 33.2 34.1 37.0 50.5 33.5 38.3 36.6 35.7 35.8 33.8 38.3 33.0 28.0 25.6 14.4 9.4 33.1 23.6 40.7 114.5 19.4 28.2 25.0 37.2 120.9 55.8 50.4 36.8 29.2 160.3 17.6 38.7 248.4 103.2 18.7 34.0 34.4 34.8 18.0 31.7 10.9 70.9 155.2 32.8 23.9 39.2 25.4 37.9 26.4 59.2 106.1 25.2 12.4 52.5 75.3 44.5 22.9 4.3 24.8 37.9 33.8 7.5 56.5 37.4 20.6 11.1 6.0 97.5 34.3 22.6 35.3 33.9 66.8 127.0 32.1 58.8 13.1 32.1 70.1 14.8 34.3 37.3 34.4 198.9 19.7 91.3 78.3 41.8 SOX17 ENSG00000164736 "SRY-box transcription factor 17" Q9H6I2 8 54457935-54460892 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.1" "Group enriched" "Detected in many" 8 "Adipocytes: 464.9;Endometrial ciliated cells: 377.3;Endothelial cells: 171.5;Glandular and luminal cells: 520.0" "Group enriched" "Detected in many" 4 "endometrial cancer: 122.8;ovarian cancer: 96.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "EFO-21: 108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025594, HPA068399" Enhanced Approved Nucleoplasm NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "CAB025594: , HPA068399: AB_2685981" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (1.76e-3)" "prognostic favorable (2.76e-4)" "unprognostic (1.01e-1)" "unprognostic (3.85e-2)" "unprognostic (3.34e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.62e-2)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (7.28e-3)" "unprognostic (1.12e-1)" "unprognostic (3.76e-1)" "unprognostic (1.88e-1)" 49.1 1.6 2.9 1.4 2.3 0.0 32.6 2.6 3.3 20.4 1.4 8.3 0.7 18.8 1.2 3.6 23.0 7.7 19.1 2.1 2.2 5.6 1.3 9.9 0.7 2.9 2.5 4.2 1.9 0.8 2.3 5.7 2.7 6.0 0.8 0.1 3.9 1.1 10.3 5.1 5.0 4.3 2.5 13.2 5.7 3.4 2.8 0.4 5.8 5.8 0.4 8.4 9.4 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.3 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 2.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 2.3 2.6 3.3 2.1 2.2 2.9 2.5 2.7 2.5 2.8 2.6 464.9 0.0 0.0 0.0 0.2 13.9 0.3 0.0 0.0 0.1 0.7 1.3 2.1 1.5 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.2 2.6 377.3 44.5 171.5 0.0 2.7 0.0 0.2 0.1 7.7 0.0 520.0 0.0 0.0 46.8 0.1 0.1 0.0 0.0 0.0 0.0 0.9 16.6 1.8 2.5 3.5 19.6 3.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 7.3 5.1 3.2 6.4 0.3 13.5 0.0 4.5 0.2 0.0 3.7 RP1 "DCDC4A, ORP1" ENSG00000104237 "RP1 axonemal microtubule associated" P56715 8 54509422-54871720 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "retina: 236.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 333.6;Rod photoreceptor cells: 1115.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.6;HDLM-2: 5.2;hTERT-RPE1: 2.0;RPTEC TERT1: 10.2;U-2197: 2.3" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.3" HPA042257 Enhanced NA NA "Cluster 79: Retina - Phototransduction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 46: Photoreceptor cells - Phototransduction" "HPA042257: AB_10797385" "unprognostic (3.19e-3)" "unprognostic (2.63e-3)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.70e-1)" "unprognostic (9.16e-3)" "unprognostic (6.24e-2)" "unprognostic (4.56e-2)" "unprognostic (4.13e-5)" "unprognostic (2.48e-1)" "unprognostic (2.16e-5)" "unprognostic (8.92e-2)" "unprognostic (6.18e-2)" "unprognostic (1.89e-2)" "unprognostic (8.96e-2)" 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.7 0.1 3.5 0.0 0.4 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 236.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.6 0.0 0.1 0.0 0.7 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.1 0.5 16.0 4.8 0.0 0.0 0.0 0.0 1.2 0.0 72.5 3.0 1.4 0.4 0.0 31.1 5.5 333.6 0.0 0.0 0.0 3.9 0.0 0.3 81.9 0.4 10.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 32.0 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.5 1.8 0.0 0.0 130.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 149.0 1115.8 0.0 0.0 0.4 3.2 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 306.3;Inhibitory neurons: 1019.5;Oligodendrocyte precursor cells: 721.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "REH: 2.6;RPTEC TERT1: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (7.15e-4)" "unprognostic (1.28e-3)" "unprognostic (6.98e-2)" "unprognostic (5.63e-3)" "unprognostic (7.39e-2)" "unprognostic (5.68e-3)" "unprognostic (6.33e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-3)" "unprognostic (6.63e-2)" "unprognostic (3.46e-4)" "unprognostic (2.08e-2)" "unprognostic (2.39e-2)" "unprognostic (7.36e-2)" "unprognostic (4.96e-2)" 0.1 0.2 7.6 0.5 7.1 0.0 0.0 0.9 8.1 0.3 0.0 1.7 0.2 0.1 0.2 0.5 0.1 0.2 0.7 7.0 2.2 0.1 0.0 0.0 0.4 0.1 2.2 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.4 0.6 0.3 0.5 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.1 5.8 0.5 0.0 0.0 0.4 0.3 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.6 7.1 0.9 8.1 7.0 2.2 0.1 2.2 0.0 0.0 5.8 1.1 0.5 9.6 18.7 7.8 0.1 0.4 0.6 0.0 0.6 12.5 0.1 0.3 2.1 0.0 9.3 3.7 35.5 0.1 0.4 0.1 0.0 0.1 0.9 0.6 0.2 2.4 0.0 0.0 306.3 0.9 0.1 2.3 0.0 1.1 0.0 0.2 1.1 0.4 0.1 0.0 1019.5 0.0 0.0 0.0 1.0 0.0 0.0 1.4 8.8 30.0 1.8 0.6 0.0 721.3 9.4 0.4 0.0 0.0 0.4 0.6 0.0 0.1 5.2 1.6 0.0 2.6 0.4 1.1 0.1 0.2 0.9 0.1 0.5 0.1 0.0 0.7 TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA018216: AB_2205185, HPA019173: AB_1858129" "unprognostic (4.43e-2)" "unprognostic (3.10e-2)" "unprognostic (8.04e-2)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (1.63e-1)" 8.9 12.9 5.8 8.2 6.5 10.9 13.1 13.2 8.4 10.3 14.5 13.9 12.7 10.5 14.3 13.0 22.0 10.8 6.0 6.6 5.8 17.4 12.8 10.2 9.5 5.2 5.5 13.4 10.6 17.6 5.7 11.9 4.7 13.3 14.5 11.4 12.5 10.2 5.0 14.3 12.8 9.5 4.6 8.3 11.1 8.3 5.6 11.0 16.5 5.3 9.2 11.8 7.6 10.0 22.3 13.4 21.5 13.1 17.0 20.3 38.5 19.6 14.6 18.2 17.1 18.3 41.3 24.0 21.8 12.7 22.5 27.0 17.0 25.5 20.2 33.3 19.2 29.0 12.4 19.5 19.1 12.7 15.7 14.1 38.1 18.4 43.2 26.0 16.3 24.9 29.2 23.6 26.3 11.8 31.8 17.0 24.1 46.1 6.5 22.6 8.9 15.7 29.9 16.9 18.0 16.2 12.6 20.3 39.9 27.7 30.2 16.0 13.2 13.8 17.6 23.6 16.2 20.1 27.4 31.4 18.7 20.6 21.1 35.0 7.6 5.9 7.8 5.0 11.1 10.0 9.1 8.1 8.3 9.7 7.5 10.9 8.4 9.4 9.3 7.6 7.4 4.4 5.8 6.5 13.2 8.4 6.6 5.8 5.2 5.5 4.7 4.6 5.6 10.0 10.5 12.8 12.7 10.7 13.4 34.2 28.0 38.4 19.9 18.2 14.2 12.1 5.2 15.7 30.4 25.8 14.6 32.9 14.6 15.3 13.7 16.4 2.3 42.0 10.4 11.1 15.0 20.0 17.0 8.0 21.1 12.2 13.3 10.4 5.7 12.6 11.4 12.5 13.2 21.9 21.6 26.5 40.7 12.6 11.0 1.2 13.1 9.0 7.2 20.6 13.0 17.2 9.2 26.7 16.9 15.8 21.6 13.9 14.6 26.9 17.4 22.0 66.7 15.3 26.3 9.2 10.8 16.2 15.3 17.5 35.5 22.2 11.7 15.3 15.8 29.3 TGS1 "NCOA6IP, PIMT" ENSG00000137574 "Trimethylguanosine synthase 1" Q96RS0 8 55773446-55826445 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025024, HPA029824" Supported Supported Cytosol NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Cytosol "HPA025024: AB_1854330, HPA029824: AB_2673212" "unprognostic (4.13e-2)" "unprognostic (7.46e-2)" "unprognostic (6.64e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.70e-2)" "unprognostic (1.60e-2)" "unprognostic (4.94e-2)" "unprognostic (9.32e-2)" "unprognostic (3.15e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.62e-2)" "unprognostic (7.23e-2)" "unprognostic (3.42e-1)" "unprognostic (2.85e-2)" 5.9 4.0 1.8 5.0 1.4 7.2 5.5 3.8 2.3 5.0 2.5 4.9 3.1 5.9 4.1 5.7 5.8 4.1 3.5 1.5 1.5 5.5 4.0 4.5 8.5 1.2 1.3 6.0 4.0 6.8 4.0 4.2 1.3 4.5 4.6 2.5 4.9 5.7 7.4 6.4 5.5 4.6 1.1 5.7 4.5 4.9 1.6 9.5 5.4 2.6 8.5 7.3 5.1 1.9 12.0 9.0 10.2 12.7 9.7 8.2 10.3 10.9 11.6 11.9 12.3 8.5 10.7 27.7 7.0 8.5 8.5 10.8 24.3 14.7 16.3 17.2 8.7 31.6 10.6 5.1 13.1 16.8 9.4 9.7 10.1 11.4 22.7 5.2 9.5 16.0 24.8 9.9 9.6 9.4 36.0 10.6 35.0 16.8 3.6 26.4 7.1 8.2 10.6 12.0 10.6 13.3 19.4 8.0 10.4 10.5 10.9 9.7 9.7 8.4 10.6 9.8 10.4 8.5 6.3 32.1 8.5 13.6 11.3 5.0 2.7 4.3 5.1 2.8 6.0 4.6 4.8 4.7 2.4 4.8 5.2 5.2 3.4 3.3 3.9 5.2 4.2 2.6 1.8 1.4 3.8 2.3 1.5 1.5 1.2 1.3 1.3 1.1 1.6 1.9 29.8 48.1 35.2 15.7 41.6 37.0 36.8 25.7 35.3 30.6 21.8 34.7 15.5 20.0 37.9 51.5 22.9 29.6 30.4 10.8 3.9 20.3 3.7 28.2 42.6 27.2 10.7 49.2 28.9 25.2 26.7 32.4 23.4 27.6 50.0 24.3 20.7 17.2 20.3 21.9 30.0 23.3 16.2 16.8 12.2 4.6 29.5 22.2 7.2 12.2 26.1 27.7 29.9 34.7 19.9 22.2 12.1 23.0 32.7 42.3 10.9 17.7 25.5 29.5 26.3 40.5 25.7 88.2 78.3 33.5 26.1 22.4 41.2 35.2 22.5 31.9 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 RPS20 "S20, uS10" ENSG00000008988 "Ribosomal protein S20" P60866 8 56067254-56074510 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003570 Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 210000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA003570: AB_1856466" "unprognostic (2.57e-2)" "unprognostic (6.91e-2)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (3.51e-1)" "unprognostic (1.99e-1)" "unprognostic (9.40e-2)" "unprognostic (1.07e-1)" "unprognostic (6.75e-2)" "unprognostic (9.78e-2)" "unprognostic (4.83e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (1.21e-8)" "unprognostic (3.64e-2)" "unprognostic (8.80e-3)" "unprognostic (2.33e-3)" "unprognostic (2.19e-2)" 2422.2 1415.6 1315.1 1437.6 1380.2 4350.7 2956.6 1314.4 2021.9 2421.6 1346.7 1883.7 1075.9 1542.4 1867.0 1732.4 1773.1 1364.6 1704.0 1265.2 1344.7 1472.6 1677.3 1532.7 3682.4 1368.1 1323.4 4823.5 2312.4 967.6 1157.1 1216.1 1376.0 1847.0 1162.5 646.1 2385.0 1153.2 2332.3 2599.0 1612.4 1057.6 1411.0 2022.1 1776.0 770.6 1360.6 2421.2 1631.2 1656.7 2569.3 1939.8 2002.2 1419.8 3154.0 2878.4 2662.3 2623.1 3875.2 4572.0 2296.1 2060.3 3243.9 2550.2 2328.3 3056.4 2994.9 4688.2 2496.8 2293.0 1686.1 1922.9 1731.7 3416.4 2167.2 2011.7 2418.6 3834.9 2434.8 3830.1 3733.9 2152.1 2396.3 4425.9 3555.4 1638.9 4725.2 3971.6 3184.3 3477.9 3210.0 2689.0 2585.6 4101.1 5915.4 4351.3 3574.7 4325.3 1233.6 3196.9 977.9 2459.6 3093.5 3500.9 896.6 2761.2 891.7 2403.8 4246.6 2210.3 3493.0 4411.0 1954.8 1824.1 3074.6 2401.4 3337.6 2829.2 2756.3 3479.1 2754.4 3895.2 1655.6 2076.5 2125.0 869.1 2514.0 1746.2 3620.8 5471.6 4594.4 3362.7 2643.7 4621.2 5940.0 4391.6 374.5 2151.7 1671.8 3772.4 3333.2 8768.9 1315.1 1380.2 1314.4 2021.9 1265.2 1344.7 1368.1 1323.4 1376.0 1411.0 1360.6 1419.8 531.6 1259.6 2162.2 18.6 2262.9 3750.0 3713.6 2367.9 409.2 140.6 956.6 590.0 1017.9 1684.3 1791.9 693.4 112.6 2885.6 1645.2 793.6 2201.1 1970.4 1979.3 746.1 1507.7 1533.9 1208.0 1268.8 13.3 4091.1 4246.0 1266.3 189.1 983.9 1670.0 570.3 2543.6 2301.4 2511.0 55.5 11.6 2235.2 679.5 3405.9 3567.2 1769.8 4496.9 1619.2 1949.5 15.0 3676.2 815.3 2747.7 10.1 16.2 3313.5 1714.9 1990.1 364.9 3196.6 1259.1 3235.5 956.0 354.6 1400.3 1958.0 1531.1 1536.1 1483.5 473.0 3924.2 3019.4 2078.3 664.6 2291.2 4097.9 MOS ENSG00000172680 "MOS proto-oncogene, serine/threonine kinase" P00540 8 56112942-56113982 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Proto-oncogene "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Early spermatids: 6.5;Spermatocytes: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 66: Spermatocytes - Spermatogenesis" "unprognostic (3.28e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PLAG1 ZNF912 ENSG00000181690 "PLAG1 zinc finger" Q6DJT9 8 56160909-56211324 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 32.0;Microglial cells: 28.1;Rod photoreceptor cells: 27.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 16.0;ASC TERT1: 20.9;hTERT-HME1: 15.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA072290 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA072290: AB_2686508" "unprognostic (1.89e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-3)" "unprognostic (1.63e-4)" "unprognostic (6.81e-2)" "unprognostic (1.07e-1)" "unprognostic (5.63e-3)" "unprognostic (8.56e-2)" "unprognostic (1.18e-1)" "unprognostic (7.99e-2)" "unprognostic (3.42e-2)" "unprognostic (1.97e-1)" "unprognostic (1.32e-3)" "unprognostic (2.83e-2)" "unprognostic (3.94e-1)" "unprognostic (1.21e-2)" "unprognostic (6.14e-2)" 0.7 1.4 0.8 1.0 1.2 0.9 0.9 2.5 1.1 3.0 0.6 0.8 1.4 1.4 4.1 0.7 3.1 0.7 3.1 0.7 1.0 1.3 0.3 1.9 1.8 1.5 1.4 4.9 0.8 1.2 3.8 1.6 1.8 1.3 0.6 7.7 3.0 1.8 0.4 1.4 2.3 0.4 1.2 2.6 1.3 2.4 1.3 2.8 1.3 1.4 2.3 1.3 3.0 2.0 2.0 0.0 11.9 0.1 16.0 20.9 3.7 5.4 6.9 2.5 1.1 0.8 6.2 0.2 5.1 2.9 0.7 0.4 3.4 7.1 2.5 0.2 7.4 8.0 0.8 1.8 3.3 2.5 2.3 14.9 3.9 1.4 15.6 6.9 4.7 5.3 3.4 0.1 5.3 0.1 0.7 4.7 3.4 0.5 1.8 6.1 0.8 4.9 3.2 0.7 0.1 0.0 0.1 0.1 0.4 8.0 0.1 2.4 7.2 3.6 4.6 5.9 1.4 1.8 1.5 2.9 4.1 0.9 1.0 0.6 0.0 0.4 0.1 0.0 0.1 1.3 0.4 0.2 0.0 0.7 1.8 1.8 0.4 0.3 0.2 0.1 0.1 0.4 0.8 1.2 2.5 1.1 0.7 1.0 1.5 1.4 1.8 1.2 1.3 2.0 2.6 6.4 3.2 2.9 13.0 1.0 2.5 6.2 1.8 23.6 1.6 0.6 12.2 4.3 6.7 5.5 25.0 8.3 2.0 1.0 0.0 0.7 6.2 3.0 2.3 3.7 5.4 5.0 16.8 1.3 4.2 4.0 2.6 4.2 1.3 0.4 15.7 0.7 5.8 32.0 12.3 3.6 6.1 2.9 2.2 6.7 15.2 2.8 16.0 28.1 1.2 16.3 4.1 2.0 19.2 1.4 4.1 10.1 6.3 5.0 5.1 0.8 9.1 27.8 0.0 2.4 1.4 9.0 8.8 1.1 0.9 7.1 4.5 0.9 3.6 12.9 CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" 24.9 20.2 25.8 30.0 27.1 29.2 25.8 30.8 32.5 22.9 25.2 30.7 33.2 18.6 46.0 22.8 24.5 17.1 41.6 26.6 26.6 42.2 26.2 28.0 39.4 27.0 26.3 49.1 26.9 36.0 38.1 19.3 27.3 26.4 30.2 32.6 35.3 21.0 37.5 21.3 36.0 18.5 28.6 46.3 27.7 11.7 26.7 36.5 28.0 39.7 38.1 28.1 24.2 28.7 59.3 18.9 39.4 13.1 100.9 71.3 42.4 41.0 37.0 30.7 23.0 46.2 68.9 54.7 34.8 23.6 43.6 32.3 40.7 61.3 38.6 24.5 77.4 83.6 45.5 66.2 51.8 72.1 52.0 86.2 54.2 22.2 98.0 43.8 32.8 100.0 41.8 34.9 74.1 29.0 72.2 106.5 35.1 93.5 25.6 82.0 12.0 46.3 57.3 63.3 10.2 7.0 21.8 32.2 31.2 47.8 34.1 40.5 49.0 16.5 35.4 53.7 39.5 37.1 40.3 93.5 46.0 105.3 28.9 55.2 37.8 53.3 42.4 38.2 40.2 60.4 46.9 43.5 44.1 52.5 55.0 49.6 15.2 49.7 35.0 62.6 60.1 33.9 25.8 27.1 30.8 32.5 26.6 26.6 27.0 26.3 27.3 28.6 26.7 28.7 31.7 19.2 77.9 2.6 72.5 20.8 44.1 49.0 16.5 31.4 37.1 27.1 93.7 35.8 48.0 49.7 14.6 44.0 66.0 75.4 125.2 41.4 27.5 25.2 15.9 29.8 39.6 32.6 9.1 75.4 80.8 26.3 92.8 32.2 53.8 13.8 42.8 78.4 162.3 13.5 8.0 66.3 34.6 67.8 45.3 13.4 37.0 58.0 53.4 14.0 68.5 50.8 60.8 1.5 6.5 65.4 63.9 30.9 59.3 45.3 115.0 82.3 41.5 37.9 13.1 23.9 39.0 51.4 39.4 34.7 23.9 42.1 61.7 21.7 73.5 48.8 SDR16C5 "EPHD-2, RDH-E2, RDHE2" ENSG00000170786 "Short chain dehydrogenase/reductase family 16C member 5" Q8N3Y7 8 56300005-56320776 "Enzymes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 51.9;lung: 34.4;skin 1: 62.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal respiratory cells: 325.1;Club cells: 141.9;Ionocytes: 120.1;Pancreatic endocrine cells: 99.5;Respiratory ciliated cells: 82.5;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 35 "memory B-cell: 4.7;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 47 "B-cells: 4.7" "Cell line enhanced" "Detected in some" "CAPAN-2: 20.8;HaCaT: 10.3;hTCEpi: 16.7;OE19: 24.8;T-47d: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA025224 Enhanced NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA025224: AB_1856163" "unprognostic (1.66e-1)" "unprognostic (8.88e-2)" "unprognostic (9.46e-2)" "unprognostic (4.18e-4)" "unprognostic (8.83e-3)" "prognostic favorable (7.88e-4)" "unprognostic (1.66e-1)" "unprognostic (2.51e-1)" "unprognostic (2.42e-1)" "unprognostic (1.78e-3)" "unprognostic (2.39e-1)" "unprognostic (2.48e-5)" "unprognostic (2.55e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-1)" 0.3 0.2 1.7 3.0 1.8 0.0 9.1 1.6 4.4 15.6 0.5 2.2 2.3 0.0 0.0 51.9 0.2 0.4 0.2 2.2 1.5 0.1 0.0 34.4 0.4 4.8 2.0 0.2 0.4 0.0 0.5 0.0 4.9 0.3 3.9 1.1 16.8 0.0 0.3 62.6 15.7 0.2 0.9 0.0 18.1 0.8 2.8 0.3 0.0 0.2 21.9 6.3 24.9 1.8 4.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 10.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 24.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.8 1.6 4.4 2.2 1.5 4.8 2.0 4.9 0.9 2.8 1.8 1.7 48.1 155.9 0.0 1.7 51.1 6.2 325.1 4.6 0.3 5.5 2.4 0.2 5.7 141.9 0.0 0.0 0.0 0.0 7.1 0.0 0.7 0.4 0.0 0.1 2.3 0.0 0.0 4.3 1.4 0.0 0.9 10.2 0.1 3.8 0.0 0.0 0.0 0.0 0.0 1.1 19.7 120.1 0.0 3.6 0.4 0.6 0.4 3.6 0.0 0.6 12.3 0.0 0.0 0.3 99.5 3.4 0.0 0.0 9.5 0.3 0.0 82.5 1.6 0.0 0.1 4.9 0.3 5.5 36.6 72.2 0.0 0.6 0.0 5.3 26.0 PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 376.2;brain: 164.1;testis: 129.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 758.4;Leydig cells: 1137.9;Peritubular cells: 225.7;Spermatocytes: 274.1" "Cancer enhanced" "Detected in many" "lung cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 14.3;ASC TERT1: 8.6;BJ: 7.7;THP-1: 7.7" "Region enriched" "Detected in all" 7 "basal ganglia: 3626.9" "Region enriched" "Detected in all" 7 "basal ganglia: 923.2" "HPA013138, CAB016390" Enhanced "Secreted in other tissues" NA NA 220000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "CAB016390: AB_2161515, HPA013138: AB_1855191" "unprognostic (6.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.71e-2)" "unprognostic (1.17e-3)" "unprognostic (1.56e-2)" "unprognostic (3.58e-3)" "unprognostic (1.31e-2)" "unprognostic (3.60e-1)" "unprognostic (6.34e-2)" "unprognostic (5.73e-2)" "unprognostic (3.47e-2)" "unprognostic (4.24e-2)" "unprognostic (1.73e-3)" "unprognostic (1.11e-1)" "unprognostic (4.48e-2)" "unprognostic (3.98e-3)" 8.6 376.2 29.9 4.4 164.1 0.0 4.9 45.2 45.6 9.2 0.5 23.1 1.1 8.1 0.0 1.4 7.6 12.5 25.6 2.7 74.0 0.2 0.2 3.7 0.1 81.4 15.9 29.7 1.1 0.0 17.1 2.9 51.3 22.4 2.0 0.6 2.7 23.4 3.0 0.8 4.2 4.6 54.0 0.1 10.0 129.0 38.0 0.2 1.0 5.3 0.1 0.6 6.2 10.1 0.0 0.0 0.1 0.0 14.3 8.6 0.0 7.7 2.5 1.3 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 29.9 164.1 45.2 45.6 2.7 74.0 81.4 15.9 51.3 54.0 38.0 10.1 0.2 0.0 1.5 0.3 0.5 0.1 0.2 758.4 0.0 0.3 0.1 0.6 0.8 0.0 8.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 85.7 0.1 3.1 0.9 0.0 0.0 0.4 0.0 0.1 16.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 15.4 0.0 2.0 0.0 0.7 60.8 1137.9 1.2 0.0 1.9 0.0 0.0 0.0 0.5 0.4 0.0 0.0 225.7 0.0 0.2 0.0 0.0 3.6 0.0 6.6 1.7 1.2 274.1 19.1 0.1 0.4 0.0 0.2 3.1 0.0 0.0 BPNT2 "FLJ20421, gPAPP, IMPA3, IMPAD1" ENSG00000104331 "3'(2'), 5'-bisphosphate nucleotidase 2" Q9NX62 8 56957931-56993867 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 22.6;Cardiomyocytes: 53.8;Cytotrophoblasts: 18.0;dendritic cells: 16.2;Extravillous trophoblasts: 91.8;Hofbauer cells: 26.6;Syncytiotrophoblasts: 33.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009411 Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 480000 "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA009411: AB_1079138" "unprognostic (1.62e-2)" "unprognostic (7.89e-3)" "unprognostic (6.58e-2)" "unprognostic (6.42e-2)" "unprognostic (2.00e-1)" "unprognostic (8.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.67e-2)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (4.24e-3)" "unprognostic (1.41e-1)" "unprognostic (1.43e-2)" "unprognostic (1.68e-3)" "unprognostic (2.89e-1)" "unprognostic (1.68e-1)" "unprognostic (1.05e-1)" 37.6 37.3 14.8 16.1 19.9 12.4 19.3 19.2 19.8 25.5 8.9 17.4 13.3 21.9 16.2 19.1 13.4 16.5 29.4 16.0 17.9 23.4 36.2 17.2 12.3 17.2 17.6 11.8 19.6 35.6 13.7 24.9 17.7 31.0 17.6 19.7 21.9 23.6 37.4 14.3 12.7 25.7 15.3 15.5 16.9 16.5 18.0 15.4 27.1 30.1 13.3 22.4 12.2 29.3 42.4 34.5 26.0 26.9 78.2 53.3 35.7 62.9 60.9 44.1 38.3 17.4 29.2 26.3 47.0 67.3 31.2 33.7 31.8 42.5 65.0 36.4 22.7 51.4 23.0 31.2 48.5 33.0 35.1 43.2 41.6 39.7 63.9 40.8 59.5 24.3 22.5 46.1 48.9 22.1 40.6 19.8 19.2 48.1 12.7 27.9 23.4 29.7 46.0 24.9 10.1 28.1 35.3 42.9 36.3 27.1 38.4 23.9 50.1 59.3 34.2 59.2 45.8 47.5 42.5 27.8 81.0 27.0 37.3 1.8 0.9 0.5 0.9 0.6 0.7 0.7 0.6 0.5 0.7 0.9 0.6 1.1 2.5 3.2 2.6 1.0 0.4 0.3 14.8 19.9 19.2 19.8 16.0 17.9 17.2 17.6 17.7 15.3 18.0 29.3 22.6 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 18.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 91.8 14.4 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 33.8 1.8 0.0 0.0 0.0 FAM110B "C8orf72, MGC39325" ENSG00000169122 "Family with sequence similarity 110 member B" Q8TC76 8 57994509-58204279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Inhibitory neurons: 195.6;Oligodendrocyte precursor cells: 253.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 13.4;intermediate monocyte: 3.5;non-classical monocyte: 6.8" "Group enriched" "Detected in many" 11 "granulocytes: 13.4;monocytes: 6.8" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008318, HPA011781" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Mitochondria, Cytosol" "HPA008318: AB_1853892, HPA011781: AB_1853891" "unprognostic (2.07e-1)" "unprognostic (6.91e-2)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.88e-8)" "unprognostic (4.09e-2)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" "unprognostic (1.44e-1)" "unprognostic (2.02e-1)" "unprognostic (8.72e-2)" "prognostic favorable (1.44e-4)" "unprognostic (1.06e-2)" "prognostic favorable (4.31e-8)" "unprognostic (2.23e-3)" "unprognostic (1.97e-1)" "unprognostic (1.37e-1)" "unprognostic (1.15e-4)" 6.6 1.3 14.1 1.9 11.5 2.2 5.2 18.1 12.0 7.9 8.1 6.6 0.8 5.7 2.2 1.3 5.0 2.7 15.7 15.2 18.1 5.6 5.6 3.8 0.7 11.7 11.2 5.3 1.6 10.9 3.8 2.7 14.0 5.3 1.4 4.0 5.8 6.7 12.0 2.8 3.2 6.0 8.2 20.5 4.6 6.1 11.9 0.7 6.1 6.0 0.7 6.3 4.9 7.4 0.0 1.1 3.9 0.1 1.7 0.6 1.5 7.5 8.6 5.1 2.3 0.0 0.1 0.0 1.4 5.3 4.6 0.0 3.5 0.0 3.9 0.0 3.6 0.7 1.1 4.5 5.8 1.0 0.2 6.1 1.4 0.2 3.2 0.6 0.0 1.7 0.0 0.1 3.9 0.1 0.0 2.7 3.7 5.3 1.6 0.0 4.3 0.0 12.8 0.8 3.7 4.1 0.0 0.5 0.2 4.5 3.4 0.4 0.0 3.6 2.3 0.0 2.6 1.6 0.0 0.0 1.7 0.0 4.3 0.0 1.4 13.4 0.0 3.5 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.5 0.0 6.8 0.0 0.1 0.7 14.1 11.5 18.1 12.0 15.2 18.1 11.7 11.2 14.0 8.2 11.9 7.4 4.2 0.0 5.5 39.2 0.5 9.8 22.8 0.2 3.4 10.6 8.9 6.6 27.7 1.5 0.9 23.9 2.1 1.7 0.1 0.1 7.9 8.7 5.8 1.0 10.9 7.5 7.2 0.0 37.5 2.9 21.9 28.1 9.2 2.5 4.5 5.4 14.6 8.0 4.9 6.7 195.6 0.2 4.1 8.7 10.2 2.2 9.9 6.6 16.0 43.1 1.3 20.1 0.0 253.8 9.2 1.7 0.1 14.7 0.2 17.4 0.0 8.8 0.7 6.6 32.9 38.1 19.8 1.2 2.5 1.0 4.1 1.5 1.0 0.5 0.0 6.7 UBXN2B p37 ENSG00000215114 "UBX domain protein 2B" Q14CS0 8 58411359-58451501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.8" "Group enriched" "Detected in all" 5 "granulocytes: 42.8;monocytes: 12.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045278 Uncertain Approved Nucleoplasm No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "HPA045278: AB_10963578" "unprognostic (1.98e-3)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (2.15e-3)" "unprognostic (1.63e-1)" "unprognostic (2.22e-1)" "unprognostic (2.46e-1)" "unprognostic (8.71e-2)" "unprognostic (3.36e-1)" "unprognostic (5.97e-2)" "unprognostic (1.58e-2)" "unprognostic (1.54e-1)" "unprognostic (6.48e-3)" "unprognostic (1.26e-1)" "unprognostic (8.22e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-2)" 7.9 9.1 10.3 12.0 11.4 15.4 11.0 14.0 12.5 6.6 9.2 8.7 7.7 8.1 10.8 5.8 8.5 8.6 9.8 11.9 9.0 15.7 18.8 9.7 9.1 11.2 8.9 9.0 8.8 16.1 7.9 7.6 11.2 9.5 9.2 13.4 12.9 8.5 9.0 6.4 7.8 9.8 9.6 10.1 8.2 9.5 9.8 11.9 14.2 11.0 9.4 8.9 4.3 12.8 11.1 20.2 16.9 20.9 3.0 1.5 11.7 6.7 12.3 8.2 10.6 8.8 20.4 13.0 13.4 8.3 22.2 9.9 25.1 12.1 11.5 10.0 12.7 16.2 17.0 11.0 12.6 14.5 15.1 5.4 19.0 3.8 18.9 19.5 10.2 19.7 11.4 23.8 7.4 11.3 26.0 16.0 22.1 38.6 4.8 14.5 7.5 8.9 26.4 16.8 6.2 25.4 11.6 11.7 19.7 16.5 23.7 17.3 2.3 6.3 13.4 13.7 14.0 12.4 13.3 18.0 20.6 13.6 8.5 15.8 11.9 18.0 4.3 11.0 4.2 3.4 4.1 3.6 5.9 3.3 4.9 4.3 42.8 5.4 12.9 2.9 5.3 5.3 10.3 11.4 14.0 12.5 11.9 9.0 11.2 8.9 11.2 9.6 9.8 12.8 4.0 9.6 8.7 27.7 11.4 5.7 10.6 10.3 4.0 16.0 13.7 11.7 18.4 10.0 9.0 11.0 22.9 15.9 10.4 15.9 9.8 11.2 35.8 8.6 9.3 4.7 12.0 13.5 55.3 11.1 17.6 9.5 10.7 11.8 23.5 13.3 4.6 17.1 23.0 11.8 62.4 9.6 14.2 32.4 12.4 61.8 10.5 27.5 8.8 21.5 26.0 13.6 15.5 43.2 41.4 10.8 8.2 14.7 8.4 10.4 15.5 29.7 8.9 25.6 0.0 13.9 8.5 20.4 17.8 9.3 6.7 8.6 10.9 8.6 9.1 10.4 CYP7A1 CYP7 ENSG00000167910 "Cytochrome P450 family 7 subfamily A member 1" P22680 8 58490178-58500163 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "liver: 49.5" "Cell type enriched" "Detected in single" 17 "Hepatocytes: 7.0" "Cancer enriched" "Detected in single" 96 "liver cancer: 28.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-2)" "prognostic favorable (3.19e-4)" "unprognostic (7.60e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (2.64e-1)" "unprognostic (8.43e-3)" "unprognostic (3.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.51e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SDCBP "MDA-9, SYCL" ENSG00000137575 "Syndecan binding protein" O00560 8 58552924-58582859 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 959.8;Melanocytes: 889.4" "Cancer enriched" "Detected in all" 4 "melanoma: 244.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1908.0" "Group enriched" "Detected in all" 5 "granulocytes: 1908.0;monocytes: 562.9" "Cell line enhanced" "Detected in many" "HHSteC: 787.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012245, HPA023840" Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" "Intracellular and membrane" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Nuclear membrane" "CAB012245: , HPA023840: AB_1857712" "unprognostic (2.39e-2)" "unprognostic (3.34e-2)" "unprognostic (1.84e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (2.60e-3)" "unprognostic (7.14e-2)" "unprognostic (1.04e-3)" "unprognostic (1.11e-1)" "unprognostic (5.68e-2)" "unprognostic (3.05e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (3.14e-1)" "unprognostic (8.02e-2)" "unprognostic (2.82e-2)" "unprognostic (2.92e-1)" 228.5 126.4 94.1 160.8 111.8 245.6 167.1 102.0 130.1 160.9 112.2 119.6 83.1 109.8 83.6 88.8 95.7 194.8 120.6 103.7 112.6 126.6 174.0 223.9 121.2 113.7 103.8 89.1 80.8 132.9 45.8 264.3 113.5 70.8 134.7 26.8 124.9 78.3 65.9 84.8 92.8 151.2 107.4 203.0 130.0 41.1 110.8 129.9 120.7 113.7 92.8 248.8 91.9 123.7 123.5 185.9 194.2 101.4 711.7 607.1 86.1 122.9 439.6 175.3 228.9 74.8 250.7 0.4 194.8 166.4 321.2 49.7 106.0 142.4 215.7 22.6 91.3 184.3 156.0 60.6 787.9 47.7 287.1 417.9 188.1 176.5 525.2 273.0 428.0 125.2 92.3 104.6 403.4 32.4 104.1 55.9 122.2 478.6 52.3 49.6 59.4 24.3 282.1 127.0 84.9 153.5 133.8 56.1 630.0 213.8 51.0 127.9 382.3 168.8 72.5 200.8 81.5 31.4 45.6 74.8 428.9 0.5 155.1 777.4 562.9 528.1 61.2 349.6 78.0 69.4 82.0 67.3 251.8 61.0 103.9 80.2 1908.0 42.6 329.1 69.9 103.0 453.2 94.1 111.8 102.0 130.1 103.7 112.6 113.7 103.8 113.5 107.4 110.8 123.7 382.7 211.5 115.9 26.8 170.3 338.7 321.2 312.5 108.1 10.8 86.7 54.6 70.6 88.6 181.3 206.0 16.7 284.3 220.2 192.9 225.0 392.9 7.8 110.9 87.0 412.7 112.3 116.6 18.5 291.6 756.8 308.1 162.1 120.5 396.9 62.9 378.3 101.9 782.5 15.2 23.7 180.3 248.2 552.1 959.8 15.9 233.9 626.0 889.4 71.2 312.4 94.3 51.5 21.6 16.3 297.9 152.9 159.9 65.1 307.4 78.4 211.2 169.8 11.1 98.6 82.7 177.4 14.8 8.4 73.3 173.2 483.0 256.2 117.0 129.2 457.6 NSMAF "FAN, GRAMD5" ENSG00000035681 "Neutral sphingomyelinase activation associated factor" Q92636 8 58583508-58659853 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 89.7;Inhibitory neurons: 94.9;Oligodendrocyte precursor cells: 102.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023067, HPA023148, HPA023151" Uncertain Approved Nucleoli NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 3: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoli "HPA023067: AB_1854653, HPA023148: AB_10670028, HPA023151: AB_1854654" "unprognostic (1.09e-1)" "unprognostic (1.94e-1)" "unprognostic (1.75e-1)" "unprognostic (8.86e-3)" "unprognostic (2.69e-1)" "unprognostic (8.73e-2)" "unprognostic (2.96e-3)" "unprognostic (9.03e-2)" "unprognostic (2.29e-1)" "unprognostic (8.11e-2)" "unprognostic (1.52e-1)" "unprognostic (4.44e-1)" "prognostic unfavorable (4.61e-9)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (2.38e-1)" "unprognostic (1.69e-1)" 16.8 14.9 8.5 16.1 9.5 7.9 13.5 9.0 9.8 14.2 9.7 15.7 9.3 13.9 9.1 13.1 10.8 10.7 11.9 8.4 9.1 9.4 5.7 12.0 21.6 9.3 9.0 12.1 17.1 17.5 10.4 13.4 9.2 12.1 14.5 4.8 11.3 12.5 18.5 19.2 14.8 14.1 8.7 16.8 14.0 5.5 10.5 35.8 13.5 15.4 22.2 16.2 13.3 10.0 33.7 32.7 14.3 20.1 53.8 43.3 24.8 26.8 58.5 36.3 33.9 17.8 20.6 40.5 21.6 41.6 37.6 26.6 24.7 21.2 41.3 46.0 13.7 75.7 19.8 20.5 67.8 33.7 51.1 29.2 33.7 26.2 99.5 29.6 36.5 36.9 32.9 29.1 41.6 25.7 71.5 26.6 25.7 27.0 12.6 26.7 21.2 11.6 19.8 26.4 13.1 16.5 22.4 8.3 24.8 18.6 20.1 41.8 34.4 35.7 21.7 48.2 27.3 5.5 2.6 31.6 52.3 25.6 23.1 8.3 7.1 4.7 6.0 5.0 6.2 4.2 6.4 6.5 14.0 4.0 4.4 4.3 14.6 6.4 3.6 4.7 8.6 4.7 8.5 9.5 9.0 9.8 8.4 9.1 9.3 9.0 9.2 8.7 10.5 10.0 9.6 9.6 5.9 68.9 28.4 18.4 10.4 7.2 26.2 9.7 7.8 6.9 15.8 1.5 9.6 9.2 4.2 12.1 17.4 8.9 3.9 7.7 0.3 5.9 14.5 12.1 14.4 12.2 89.7 8.8 8.3 13.8 14.8 7.8 28.5 15.8 5.3 4.0 17.8 32.0 94.9 10.4 2.0 31.0 35.3 2.1 16.4 33.9 10.6 54.4 22.6 6.3 13.4 102.1 51.2 7.4 9.1 12.8 18.3 13.0 8.0 4.9 3.8 6.3 6.6 18.0 10.8 2.0 3.5 16.1 17.8 9.3 22.7 10.6 10.7 11.0 TOX "KIAA0808, TOX1" ENSG00000198846 "Thymocyte selection associated high mobility group box" O94900 8 58805412-59119147 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 52.4" "Group enriched" "Detected in many" 5 "Astrocytes: 316.3;Excitatory neurons: 198.3;Inhibitory neurons: 155.0;Oligodendrocyte precursor cells: 455.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 36.6" "Group enriched" "Detected in many" 5 "granulocytes: 21.5;NK-cells: 18.4;T-cells: 36.6" "Cell line enhanced" "Detected in many" "JURKAT: 75.9;MOLT-4: 149.1;SH-SY5Y: 43.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018322, HPA073241" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli fibrillar center" "HPA018322: AB_1858199, HPA073241: AB_2686584" "unprognostic (7.60e-4)" "unprognostic (6.16e-3)" "unprognostic (5.65e-2)" "unprognostic (2.27e-1)" "unprognostic (9.53e-2)" "unprognostic (4.52e-1)" "unprognostic (1.22e-1)" "prognostic favorable (5.20e-4)" "unprognostic (1.46e-1)" "unprognostic (3.46e-3)" "unprognostic (6.73e-3)" "unprognostic (4.66e-2)" "prognostic unfavorable (1.90e-7)" "unprognostic (1.12e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-1)" "unprognostic (1.97e-1)" 0.7 1.0 7.1 5.8 9.3 2.9 1.0 0.1 10.7 1.8 0.0 11.4 9.5 1.3 0.4 3.3 0.8 4.6 0.7 6.4 8.0 3.0 1.1 4.6 18.2 2.0 4.4 5.7 1.4 2.4 1.8 1.3 2.2 2.0 8.6 6.0 1.6 1.0 0.1 0.5 10.3 2.5 0.0 5.5 7.9 6.3 5.8 52.4 1.1 0.6 18.9 2.0 1.4 4.9 0.9 0.2 15.7 0.0 1.6 3.5 0.0 3.3 7.5 1.8 0.3 0.0 0.0 0.0 0.0 14.4 0.8 1.2 3.9 0.0 0.4 0.5 1.5 0.0 2.8 0.0 12.7 2.8 0.7 1.9 0.5 2.3 2.9 1.0 25.9 75.9 0.0 0.0 1.2 0.0 149.1 0.0 2.7 0.2 0.4 3.1 10.7 0.1 0.4 0.4 14.3 43.8 0.0 0.1 0.0 3.6 0.0 0.0 0.2 3.9 1.8 12.9 4.4 0.0 0.0 9.9 0.5 0.1 2.8 21.5 0.2 3.2 12.1 0.0 5.5 5.4 8.6 18.2 1.4 1.3 3.3 9.7 0.3 18.4 0.0 0.0 36.6 5.6 7.1 9.3 0.1 10.7 6.4 8.0 2.0 4.4 2.2 0.0 5.8 4.9 0.6 9.6 31.6 316.3 12.3 1.3 0.1 0.1 1.2 18.4 0.2 0.9 1.8 1.5 2.5 1.8 0.0 3.9 23.2 3.7 0.0 0.9 2.0 1.9 2.7 1.8 46.0 4.2 198.3 0.7 0.2 2.7 6.1 0.8 16.5 0.0 0.4 0.7 3.7 0.0 155.0 34.8 2.0 0.6 9.6 2.2 0.9 2.8 0.0 47.8 0.6 14.3 34.0 455.4 5.0 2.6 9.6 0.4 22.4 0.1 4.0 1.3 10.4 2.2 0.0 0.2 0.6 1.0 0.7 0.5 1.3 0.8 35.0 0.0 10.3 0.1 CA8 "CALS, CARP" ENSG00000178538 "Carbonic anhydrase 8" P35219 8 60185412-60281400 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.3;parathyroid gland: 40.1" "Cell type enhanced" "Detected in many" "Astrocytes: 92.7;Enteroendocrine cells: 35.2;Gastric mucus-secreting cells: 40.2;Oligodendrocyte precursor cells: 129.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 7.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 24 "basophil: 76.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 76.2" "Cell line enhanced" "Detected in some" "HEK 293: 10.1;JURKAT: 11.0;K-562: 20.3;NB-4: 12.3;OE19: 17.4" "Region enriched" "Detected in all" 38 "cerebellum: 1260.5" "Region enriched" "Detected in all" 9 "cerebellum: 86.3" "HPA024748, CAB025545, CAB047309" Enhanced NA NA "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "CAB025545: , CAB047309: , HPA024748: AB_1846003" "unprognostic (1.55e-1)" "unprognostic (2.89e-2)" "unprognostic (4.43e-2)" "unprognostic (3.46e-3)" "unprognostic (6.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.85e-2)" "unprognostic (3.54e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.79e-5)" "unprognostic (3.23e-2)" "unprognostic (1.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.71e-2)" "unprognostic (1.95e-1)" "unprognostic (1.41e-1)" 1.6 0.9 5.2 0.3 5.8 0.5 4.6 18.3 5.6 4.3 2.0 1.3 1.0 1.9 10.2 0.2 1.5 0.3 4.3 4.4 5.3 5.3 0.0 0.9 0.4 4.7 4.9 0.2 1.9 40.1 8.5 6.2 5.0 1.5 2.0 2.3 3.7 0.2 1.2 0.3 1.0 0.5 3.1 0.8 4.4 4.1 5.1 1.3 0.3 2.3 0.3 0.6 0.3 4.0 0.0 2.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.1 0.0 0.1 0.0 10.1 4.5 0.0 0.0 3.6 1.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 11.0 20.3 0.2 0.0 0.0 3.3 12.3 0.2 17.4 0.0 0.0 0.0 0.2 0.4 0.8 5.1 0.0 0.0 1.1 0.0 2.0 4.5 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.5 76.2 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.1 5.2 5.8 18.3 5.6 4.4 5.3 4.7 4.9 5.0 3.1 5.1 4.0 22.0 0.0 4.8 92.7 1.6 1.0 0.4 4.1 0.0 8.2 15.6 10.3 4.7 0.0 5.7 3.7 0.0 8.3 10.9 2.0 3.9 8.1 9.9 9.8 2.4 16.7 35.2 13.5 4.7 6.0 0.3 4.0 40.2 26.2 0.0 1.1 0.0 0.0 9.9 0.0 25.6 25.0 6.1 1.9 1.1 4.9 1.5 1.1 7.2 18.7 0.0 2.6 1.0 129.7 0.4 1.6 3.5 1.5 14.0 2.1 0.3 0.0 1.2 1.0 0.0 0.8 2.3 3.8 5.5 0.2 0.4 1.4 0.7 3.1 3.3 1.5 RAB2A RAB2 ENSG00000104388 "RAB2A, member RAS oncogene family" P61019 8 60516936-60623644 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB018781 Approved NA NA 170000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" "CAB018781: AB_654960" "prognostic unfavorable (8.22e-4)" "unprognostic (1.84e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (9.02e-4)" "unprognostic (1.25e-1)" "unprognostic (6.69e-2)" "unprognostic (1.37e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-1)" "unprognostic (1.06e-1)" "unprognostic (4.25e-2)" "unprognostic (5.10e-1)" "unprognostic (7.57e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" 67.0 52.0 42.6 36.5 49.0 48.7 49.1 38.4 63.0 48.5 30.2 54.4 49.1 45.5 48.9 83.2 32.1 37.7 70.2 48.5 52.3 63.3 70.3 40.9 26.4 41.4 41.7 35.0 43.2 68.6 39.0 51.2 44.4 55.0 48.3 41.2 54.5 37.7 115.8 42.1 53.0 40.0 42.2 33.5 60.6 27.4 44.9 31.2 62.4 69.1 27.8 48.4 59.9 42.2 121.6 68.6 46.2 40.4 152.8 105.9 65.7 101.5 72.5 50.3 58.5 29.5 92.0 39.0 40.2 129.4 83.7 70.8 55.4 64.9 69.2 59.8 45.9 56.3 30.1 40.8 112.9 17.3 48.8 113.9 86.6 57.0 68.6 101.1 62.9 32.6 36.0 51.0 80.1 40.4 75.1 29.3 42.6 176.5 30.6 45.6 20.2 33.9 94.2 55.0 31.6 63.2 43.8 84.2 92.0 60.3 84.1 40.3 104.2 66.9 64.3 100.4 63.0 64.7 49.4 43.6 97.3 37.7 82.7 230.0 164.4 241.2 88.0 149.3 81.5 112.3 90.0 101.2 147.7 108.9 92.2 100.1 310.9 130.2 152.0 97.1 117.7 129.3 42.6 49.0 38.4 63.0 48.5 52.3 41.4 41.7 44.4 42.2 44.9 42.2 167.5 157.0 129.0 67.3 99.3 214.4 197.0 267.0 135.5 102.2 152.6 148.2 182.0 117.2 190.7 165.5 16.7 214.4 112.2 198.6 426.5 266.4 404.2 133.2 200.4 163.8 178.6 56.0 103.7 278.1 365.2 194.9 107.6 197.1 92.5 103.6 121.3 261.9 204.2 124.5 89.6 332.0 266.5 100.2 146.1 111.6 175.2 129.4 279.3 89.0 159.3 153.6 129.8 133.7 124.9 324.4 168.6 165.5 143.8 315.2 200.2 366.4 142.1 60.8 170.9 149.3 236.2 219.7 106.2 210.6 241.5 467.8 102.8 162.7 169.9 335.6 CHD7 "CRG, FLJ20357, FLJ20361, KIAA1416" ENSG00000171316 "Chromodomain helicase DNA binding protein 7" Q9P2D1 8 60678740-60868028 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 71.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 241.8;Oligodendrocyte precursor cells: 298.6;Oligodendrocytes: 255.7;Rod photoreceptor cells: 198.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 15 "B-cells: 14.9;granulocytes: 17.6;T-cells: 6.6" "Cell line enhanced" "Detected in many" "AF22: 51.5;SCLC-21H: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053075 Supported Nucleoplasm,Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Nucleoli "HPA053075: AB_2682035" "unprognostic (3.77e-2)" "unprognostic (3.28e-3)" "unprognostic (3.17e-2)" "prognostic unfavorable (5.34e-5)" "unprognostic (9.59e-2)" "unprognostic (1.14e-1)" "unprognostic (1.86e-3)" "unprognostic (3.41e-2)" "unprognostic (3.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (9.09e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-1)" "unprognostic (8.20e-2)" "unprognostic (2.17e-1)" 3.6 1.9 10.3 3.9 17.2 22.1 3.5 71.5 11.0 2.0 2.5 4.6 4.6 2.2 2.2 4.9 2.3 1.9 3.8 9.4 11.5 3.8 3.2 4.6 5.8 19.7 17.2 1.0 4.4 5.3 6.1 4.3 18.8 2.7 4.0 23.7 3.9 1.7 10.4 5.2 6.4 1.7 11.4 5.6 3.5 2.9 15.6 2.6 4.1 4.1 5.7 3.4 3.2 17.7 8.0 4.0 51.5 9.2 0.1 0.0 16.2 0.4 0.1 1.8 1.6 10.0 7.3 15.5 0.9 0.1 2.3 4.8 26.7 7.9 1.6 5.9 14.3 36.5 7.0 13.2 2.1 11.1 6.5 1.0 5.9 0.0 8.5 3.1 7.7 12.5 2.7 13.4 1.2 8.3 17.5 12.7 35.4 8.1 1.8 36.0 12.1 5.0 4.1 9.1 46.9 23.2 1.4 5.9 14.9 18.0 10.5 10.5 9.0 0.5 8.3 0.5 4.3 14.2 8.7 23.7 3.0 1.2 13.4 14.9 0.4 17.6 3.2 0.2 4.1 10.1 3.6 1.1 0.1 14.9 6.6 2.4 9.3 0.0 0.8 0.8 0.3 0.6 10.3 17.2 71.5 11.0 9.4 11.5 19.7 17.2 18.8 11.4 15.6 17.7 35.9 32.1 17.5 68.6 64.3 30.3 35.9 10.8 9.6 36.3 16.6 14.6 35.8 27.1 20.7 16.5 241.8 8.2 17.4 31.8 1.9 17.7 15.9 34.0 4.1 40.5 87.3 3.8 6.8 11.3 8.6 6.4 28.5 37.6 41.0 39.8 21.4 12.6 14.9 70.7 17.8 39.9 32.6 10.8 10.4 8.9 0.9 13.6 21.4 118.0 13.9 121.3 15.5 298.6 255.7 16.9 27.4 0.4 29.1 42.9 17.4 5.4 20.4 198.5 0.0 49.7 9.8 8.0 12.9 25.5 32.4 6.2 21.4 3.0 34.1 35.8 CLVS1 "C6orf212L, CRALBPL, MGC34646, RLBP1L1" ENSG00000177182 "Clavesin 1" Q8IUQ0 8 61057158-61501645 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.9;retina: 5.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 113.1;Inhibitory neurons: 158.1;Oligodendrocyte precursor cells: 90.0;Oligodendrocytes: 37.3" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Daudi: 1.5;SCLC-21H: 3.7;SH-SY5Y: 1.6;U-266/70: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076650 Approved NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA076650: " "unprognostic (1.86e-2)" "unprognostic (3.09e-4)" "unprognostic (2.79e-1)" "unprognostic (2.96e-7)" "unprognostic (1.11e-1)" "unprognostic (7.29e-2)" "unprognostic (2.99e-1)" "unprognostic (8.02e-4)" "unprognostic (2.23e-1)" "unprognostic (8.44e-3)" "unprognostic (7.25e-3)" "unprognostic (2.94e-1)" "unprognostic (5.79e-8)" "unprognostic (2.49e-1)" "unprognostic (3.19e-2)" "unprognostic (9.71e-2)" "unprognostic (1.14e-2)" 1.5 0.4 5.1 0.3 5.6 0.2 0.5 9.9 8.0 0.2 0.0 0.2 0.1 0.0 0.1 1.5 0.5 0.3 0.3 4.9 6.5 0.2 0.6 0.1 0.5 3.8 2.1 0.1 0.1 0.0 2.4 0.1 4.0 0.2 0.1 5.2 1.2 0.0 0.5 1.5 0.2 0.0 2.0 0.4 0.2 2.0 3.8 0.7 1.2 0.0 0.9 0.1 0.3 4.3 0.2 0.4 0.1 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.5 0.1 0.2 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.4 0.8 0.2 0.2 1.2 1.0 0.1 0.4 0.0 3.7 1.6 0.1 0.2 0.0 0.2 0.2 0.5 0.3 0.1 0.2 0.1 0.1 1.6 0.8 0.2 0.9 0.0 0.0 1.1 0.3 0.2 0.2 0.2 0.1 0.3 0.3 0.1 0.0 0.5 0.2 0.3 0.8 0.5 0.1 0.3 0.0 0.3 5.1 5.6 9.9 8.0 4.9 6.5 3.8 2.1 4.0 2.0 3.8 4.3 6.1 6.4 0.5 9.8 0.3 0.0 0.1 0.1 0.0 2.0 0.1 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.1 0.1 0.4 0.0 0.0 113.1 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 158.1 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.0 19.7 0.0 11.2 0.0 90.0 37.3 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.0 1.8 0.0 1.0 0.2 0.4 0.6 0.3 0.1 0.8 0.0 0.0 0.0 0.2 ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 386.9" "Cell type enhanced" "Detected in all" "Muller glia cells: 468.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-87 MG: 890.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Endoplasmic reticulum" "HPA055161: AB_2682721, HPA059303: AB_2683973" "unprognostic (8.07e-2)" "prognostic unfavorable (8.07e-5)" "unprognostic (1.73e-2)" "unprognostic (4.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.85e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (3.61e-4)" "unprognostic (6.39e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.75e-4)" "unprognostic (9.50e-2)" "prognostic unfavorable (1.57e-5)" "unprognostic (8.96e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (4.24e-4)" "unprognostic (2.74e-2)" 386.9 160.3 64.7 50.6 69.2 16.9 106.9 102.3 88.9 65.6 84.4 78.8 45.6 49.3 44.7 71.4 46.9 61.0 111.3 64.5 58.4 59.5 74.9 74.1 20.3 54.0 69.2 62.2 44.7 38.7 36.3 47.9 52.2 48.3 84.9 219.5 101.9 70.2 357.6 35.2 45.5 67.5 44.8 28.6 105.0 16.5 71.8 16.7 97.0 182.7 28.5 112.2 43.8 60.4 460.3 652.3 89.9 55.1 392.1 370.1 31.2 804.0 741.3 336.3 350.1 113.1 594.2 35.3 54.3 474.6 270.3 167.5 56.2 281.1 570.0 13.6 57.0 81.1 372.5 310.3 251.2 12.5 12.9 306.5 61.9 187.6 237.4 657.2 144.8 18.0 22.2 32.1 300.2 97.4 3.3 16.6 51.7 441.6 383.4 22.3 97.0 7.3 206.2 374.0 93.1 32.1 249.9 116.1 101.7 49.0 47.7 22.2 456.7 338.0 174.3 313.0 288.0 20.2 27.1 1.5 890.1 7.5 231.4 1.9 8.3 0.3 2.5 2.9 4.7 5.5 3.5 2.4 10.0 5.0 4.9 2.5 25.4 8.7 1.8 34.0 4.0 4.1 64.7 69.2 102.3 88.9 64.5 58.4 54.0 69.2 52.2 44.8 71.8 60.4 79.1 195.5 244.0 366.6 13.8 47.0 160.7 126.0 68.9 138.3 83.7 58.4 228.6 37.1 157.5 86.5 294.0 118.1 40.3 57.0 15.6 144.2 1.6 51.4 65.8 85.9 116.5 13.0 93.1 180.4 107.1 132.0 73.9 115.4 8.2 34.5 42.8 62.6 72.2 127.9 98.9 215.1 52.9 26.6 44.1 3.1 70.8 48.1 42.7 61.8 20.0 468.8 2.1 154.8 53.5 257.7 32.3 57.6 15.9 148.2 34.3 34.6 66.6 158.8 46.0 114.4 92.7 3.4 16.8 101.7 50.3 48.0 13.6 131.2 67.3 254.2 NKAIN3 "FAM77D, FLJ39630, NKAIN3-IT1" ENSG00000185942 "Sodium/potassium transporting ATPase interacting 3" Q8N8D7 8 62248591-63014000 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 9 "brain: 18.9" "Group enriched" "Detected in some" 6 "Astrocytes: 1258.6;Oligodendrocyte precursor cells: 811.8" "Cancer enriched" "Detected in single" 5 "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.2;SCLC-21H: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA018833 Enhanced NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA018833: AB_2669943" "unprognostic (1.28e-1)" "unprognostic (2.92e-1)" "unprognostic (1.12e-2)" "unprognostic (1.83e-1)" "unprognostic (3.56e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-3)" "unprognostic (4.88e-2)" "unprognostic (1.26e-1)" "unprognostic (3.22e-2)" "unprognostic (3.15e-2)" "unprognostic (1.58e-1)" 0.2 1.7 18.9 0.3 11.8 0.9 0.3 0.8 9.9 0.6 0.0 0.4 0.3 0.4 0.7 0.2 0.2 0.3 0.3 16.1 10.6 0.4 2.0 0.2 0.3 3.7 11.2 0.4 0.3 0.7 0.0 0.2 2.2 0.3 0.4 1.7 1.2 0.4 0.6 0.7 0.4 0.2 1.4 0.4 0.3 0.4 16.1 0.1 0.2 0.1 0.1 0.2 0.0 4.8 0.4 0.6 2.2 0.3 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.6 0.5 0.3 0.2 0.2 0.2 0.5 0.1 0.1 0.4 0.1 0.9 1.2 0.3 0.1 0.5 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.3 0.5 1.3 0.1 0.2 0.3 0.5 0.8 0.4 1.1 1.9 0.3 0.2 0.0 0.6 3.7 0.3 0.3 0.4 0.2 0.6 0.3 0.4 0.4 0.5 0.5 0.4 0.3 0.6 0.5 0.2 0.6 0.4 1.2 0.9 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.2 0.5 0.2 0.2 0.2 0.1 0.0 18.9 11.8 0.8 9.9 16.1 10.6 3.7 11.2 2.2 1.4 16.1 4.8 0.0 0.0 0.0 1258.6 0.0 0.4 0.1 0.0 0.0 10.4 1.3 1.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.8 0.2 6.3 0.0 0.0 0.0 35.7 0.7 0.1 0.8 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 168.5 0.0 0.0 0.0 0.0 4.2 0.3 0.0 1.8 21.5 0.0 0.0 0.0 811.8 3.8 0.6 0.0 0.0 0.0 0.6 0.0 2.3 0.0 0.2 0.0 7.6 0.1 0.0 0.4 0.3 0.0 0.1 0.0 0.2 0.0 0.2 GGH ENSG00000137563 "Gamma-glutamyl hydrolase" Q92820 8 63014881-63039407 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 125.7;liver: 188.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 510.3;Early spermatids: 471.0;Extravillous trophoblasts: 273.4;Proximal tubular cells: 340.8;Syncytiotrophoblasts: 754.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 30.6" "Lineage enriched" "Detected in all" 5 "dendritic cells: 30.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019296, HPA025226" Approved "Intracellular and membrane" NA NA 1200000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB019296: , HPA025226: AB_1849645" "unprognostic (9.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.99e-7)" "unprognostic (5.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.65e-4)" "unprognostic (1.95e-2)" "unprognostic (1.60e-1)" "unprognostic (2.11e-2)" "unprognostic (1.32e-1)" "unprognostic (1.69e-2)" "unprognostic (9.62e-3)" "unprognostic (1.50e-1)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" 9.8 5.4 11.1 14.2 11.1 43.7 16.5 10.7 14.3 5.9 13.1 54.3 11.3 6.3 4.4 20.7 3.5 4.3 3.1 11.1 12.3 125.7 188.6 8.0 10.9 13.3 11.1 3.1 9.9 13.1 1.9 54.9 13.7 4.4 74.4 2.1 13.0 3.7 2.1 27.2 9.9 11.6 10.1 5.5 8.2 33.9 14.4 17.8 2.4 3.2 22.5 8.5 10.8 11.1 110.5 97.6 97.4 15.7 94.1 39.6 69.6 64.3 105.1 94.2 137.7 144.5 183.8 69.8 18.0 77.1 166.8 87.2 97.2 101.9 138.9 139.0 71.6 112.3 50.3 105.1 17.6 53.5 65.9 29.1 29.2 93.9 50.7 59.4 116.1 66.9 62.4 255.2 177.3 64.3 28.8 71.1 51.0 231.6 86.0 77.6 95.2 98.1 75.8 40.3 38.6 69.9 91.8 103.6 98.5 91.6 116.6 65.8 65.5 104.2 115.6 99.4 111.3 112.6 127.2 88.3 158.0 0.1 185.0 0.0 2.1 2.3 1.1 1.7 0.8 6.5 1.5 1.7 0.9 2.7 1.8 1.9 3.0 4.4 2.0 30.6 2.7 1.9 11.1 11.1 10.7 14.3 11.1 12.3 13.3 11.1 13.7 10.1 14.4 11.1 13.1 16.0 7.3 11.1 26.1 30.2 23.2 66.6 9.1 2.0 14.9 21.0 3.2 17.2 31.1 22.0 0.0 510.3 11.7 49.2 37.2 19.7 471.0 5.4 11.5 13.1 13.2 62.5 11.5 7.4 273.4 27.2 11.7 7.6 10.8 21.4 13.6 219.5 72.4 0.0 8.7 70.7 44.7 21.0 15.5 154.2 5.9 12.0 24.9 1.0 32.1 23.1 2.1 3.5 2.9 4.3 23.7 8.2 106.9 10.5 4.3 340.8 18.3 1.3 26.3 12.8 20.4 80.3 133.0 35.9 43.0 754.5 8.5 9.3 102.0 23.1 TTPA AVED ENSG00000137561 "Alpha tocopherol transfer protein" P49638 8 63048553-63086053 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "liver: 165.0" "Group enriched" "Detected in some" 4 "Astrocytes: 37.9;Hepatocytes: 72.0" "Cancer enriched" "Detected in some" 9 "liver cancer: 21.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 2.0;SK-BR-3: 6.0;T-47d: 2.1;U-2 OS: 2.9;U-2197: 3.7" "Low region specificity" "Detected in all" NA NA 10000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (7.82e-3)" "unprognostic (1.30e-7)" "unprognostic (1.78e-1)" "unprognostic (8.44e-2)" "unprognostic (1.25e-2)" "unprognostic (7.84e-2)" "unprognostic (4.04e-2)" "unprognostic (3.50e-1)" "unprognostic (5.40e-2)" "unprognostic (3.28e-1)" "unprognostic (1.14e-2)" "unprognostic (1.49e-2)" "unprognostic (3.57e-2)" "unprognostic (5.46e-3)" "unprognostic (6.16e-3)" 1.6 0.2 2.7 0.4 2.7 0.2 0.5 3.0 2.3 0.1 0.7 3.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 2.5 2.5 2.4 165.0 0.7 0.2 2.5 3.2 0.0 1.2 3.6 0.1 1.7 2.4 0.1 4.3 0.9 0.1 0.1 0.2 0.2 0.3 0.2 2.1 0.0 0.3 0.3 3.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.8 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.0 0.0 0.0 2.0 0.0 1.5 0.1 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.1 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.5 6.0 0.6 0.0 2.1 0.2 0.1 0.0 2.9 3.7 0.6 0.2 0.0 0.0 1.3 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 2.7 3.0 2.3 2.5 2.5 2.5 3.2 2.4 2.1 3.0 2.3 0.0 3.2 1.1 37.9 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 7.2 1.3 0.0 0.0 11.2 0.0 2.1 1.9 1.1 0.0 0.0 0.1 0.2 2.4 0.0 1.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 1.8 72.0 0.6 0.0 2.7 2.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 12.9 0.0 10.6 0.1 0.1 1.2 0.0 0.0 0.1 0.0 5.5 0.0 0.2 0.0 0.7 0.1 0.0 1.0 0.0 0.1 9.9 0.1 0.0 4.9 0.1 YTHDF3 FLJ31657 ENSG00000185728 "YTH N6-methyladenosine RNA binding protein 3" Q7Z739 8 63168553-63212786 "Predicted intracellular proteins" "Host-virus interaction" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 36: HEL - Hemostasis" "Cluster 44: Endometrium - Transcription" "unprognostic (1.06e-2)" "unprognostic (9.89e-3)" "unprognostic (6.65e-3)" "unprognostic (2.06e-2)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (7.87e-2)" "unprognostic (9.57e-2)" "unprognostic (2.07e-1)" "unprognostic (6.14e-2)" "unprognostic (2.24e-2)" "unprognostic (1.26e-1)" "unprognostic (3.67e-2)" "unprognostic (1.80e-1)" "unprognostic (1.51e-1)" "unprognostic (1.35e-3)" "unprognostic (1.11e-1)" 24.8 22.9 8.4 20.6 10.5 91.5 22.1 12.8 14.4 24.0 13.0 24.3 21.7 24.6 21.3 21.4 18.7 22.4 28.7 10.3 10.4 24.7 41.0 20.5 21.1 9.0 9.2 23.5 22.6 24.2 8.7 29.7 9.8 22.9 24.1 15.2 22.1 19.9 34.3 15.9 21.6 29.0 9.4 22.0 18.9 22.5 11.7 25.0 23.2 36.1 21.1 23.3 13.2 10.7 37.6 50.4 47.9 36.3 62.5 53.9 32.2 67.2 56.7 42.5 49.1 42.9 37.5 40.5 14.0 66.5 47.6 35.0 64.1 45.3 61.7 32.7 29.9 74.7 36.5 30.4 57.1 21.9 35.0 71.0 35.0 45.1 63.5 44.4 35.9 24.6 43.9 35.6 66.7 26.9 40.1 22.6 65.8 50.4 36.8 30.5 36.1 19.9 42.7 66.4 19.4 34.8 48.0 42.5 51.0 40.7 57.0 27.2 65.2 38.4 36.4 34.2 36.4 42.6 40.6 56.2 38.9 29.4 47.5 40.3 29.1 30.7 14.2 32.9 15.8 11.7 14.1 17.0 29.0 13.8 17.0 16.3 36.5 18.4 47.2 8.6 16.5 18.1 8.4 10.5 12.8 14.4 10.3 10.4 9.0 9.2 9.8 9.4 11.7 10.7 33.0 32.1 51.1 41.8 28.2 38.7 22.2 19.1 26.2 15.4 34.1 24.5 49.9 28.6 26.5 20.2 6.2 20.2 34.1 51.0 7.9 15.7 8.0 39.2 72.4 28.2 40.7 14.5 49.8 16.7 27.1 33.5 30.1 77.4 22.8 24.9 28.9 69.3 31.1 20.2 47.2 31.8 10.2 62.1 61.5 12.0 23.9 54.4 17.8 54.4 32.4 15.4 15.5 60.3 61.9 21.3 30.6 26.4 22.9 32.8 27.9 29.7 31.2 13.4 13.1 26.4 31.5 15.1 19.3 37.9 31.4 26.4 28.8 25.5 28.5 35.8 BHLHE22 "Beta3, BHLHB5, CAGL85, TNRC20" ENSG00000180828 "Basic helix-loop-helix family member e22" Q8NFJ8 8 64580365-64583627 "Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 23.2" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 64.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "THP-1: 78.4" "Group enriched" "Detected in all" 5 "amygdala: 30.7;cerebellum: 30.7;cerebral cortex: 22.7;hippocampal formation: 46.3;white matter: 13.1" "HPA064128, HPA064872, HPA067500" Enhanced Approved "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA064128: AB_2685195, HPA064872: AB_2685377, HPA067500: AB_2685855" "unprognostic (9.17e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-2)" "unprognostic (2.28e-5)" "unprognostic (7.22e-3)" "unprognostic (6.47e-4)" "unprognostic (2.41e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (6.58e-2)" "unprognostic (1.52e-1)" "unprognostic (3.71e-2)" "unprognostic (2.86e-7)" "unprognostic (3.20e-2)" "unprognostic (2.29e-1)" "unprognostic (6.72e-3)" "unprognostic (1.86e-1)" 2.0 0.5 8.9 1.4 6.6 0.0 1.5 12.1 22.4 2.3 0.4 1.3 0.4 0.3 0.1 0.9 0.8 0.4 0.3 23.2 1.5 0.2 0.5 2.0 0.7 5.5 1.5 0.2 0.7 0.1 1.4 0.0 2.6 0.4 0.5 4.4 0.5 2.3 0.1 0.8 1.4 0.4 1.4 1.4 0.5 0.2 1.1 0.3 0.7 0.0 0.6 1.2 2.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 78.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 6.6 12.1 22.4 23.2 1.5 5.5 1.5 2.6 1.4 1.1 1.8 0.3 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 64.7 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.0 3.4 0.2 0.0 0.0 0.6 1.5 0.0 1.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.2 2.9 0.0 0.4 0.1 1.6 0.0 0.1 0.0 0.0 0.0 CYP7B1 SPG5A ENSG00000172817 "Cytochrome P450 family 7 subfamily B member 1" O75881 8 64587763-64798737 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intrahepatic cholestasis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.2" "Cell type enhanced" "Detected in many" "Astrocytes: 93.7;Oligodendrocyte precursor cells: 94.5;Oligodendrocytes: 119.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "basophil: 2.5;eosinophil: 1.5" "Lineage enriched" "Detected in single" 25 "granulocytes: 2.5" "Group enriched" "Detected in some" 4 "HSkMC: 16.5;SH-SY5Y: 5.5;WM-115: 10.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017761 Uncertain NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "HPA017761: AB_1847455" "unprognostic (3.19e-2)" "unprognostic (1.91e-1)" "unprognostic (1.50e-1)" "unprognostic (6.89e-3)" "unprognostic (1.07e-1)" "unprognostic (5.80e-3)" "unprognostic (3.80e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (3.19e-2)" "unprognostic (1.87e-2)" "unprognostic (2.38e-3)" "unprognostic (4.00e-1)" "unprognostic (3.04e-3)" "unprognostic (6.75e-3)" 8.4 5.4 5.7 5.6 11.4 0.3 6.3 8.2 6.6 5.7 8.6 2.3 1.8 2.8 2.0 7.3 2.7 5.8 3.6 5.3 6.8 7.9 21.5 4.6 2.4 11.8 7.3 4.2 6.7 11.4 0.8 0.5 11.4 4.4 3.5 1.9 4.6 5.6 0.2 5.9 1.8 4.3 8.4 9.2 2.4 1.7 8.1 2.1 12.2 1.7 2.9 7.9 3.0 27.2 1.5 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 5.5 0.0 0.0 2.2 0.8 0.0 1.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.7 11.4 8.2 6.6 5.3 6.8 11.8 7.3 11.4 8.4 8.1 27.2 3.3 0.0 3.4 93.7 0.1 10.6 6.6 1.0 7.4 4.9 4.2 5.5 3.0 2.8 0.9 7.3 2.1 0.1 0.4 0.0 3.9 4.4 7.4 0.2 6.9 2.1 1.8 1.3 29.3 4.9 0.2 15.9 0.5 0.1 12.7 0.6 2.5 8.2 0.2 3.3 30.6 0.5 0.0 0.3 4.9 8.6 5.9 0.5 17.8 30.0 1.0 6.9 0.0 94.5 119.2 1.2 0.0 4.9 0.0 4.2 0.0 2.9 0.8 0.5 13.1 1.1 16.8 4.1 3.4 6.2 12.6 0.0 1.3 7.6 0.0 3.1 ARMC1 "Arcp, FLJ10511" ENSG00000104442 "Armadillo repeat containing 1" Q9NVT9 8 65602458-65634217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026085 Approved Approved Mitochondria NA NA "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA026085: AB_1845031" "prognostic unfavorable (4.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (8.18e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (7.73e-4)" "unprognostic (4.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.19e-2)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.81e-1)" "unprognostic (3.30e-3)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "unprognostic (1.66e-1)" 16.6 15.4 19.0 13.5 23.8 13.1 18.4 21.0 29.0 15.2 16.4 16.4 15.6 18.6 16.4 16.8 13.2 11.9 21.6 19.7 21.7 22.0 23.2 12.4 19.3 19.8 20.9 18.8 14.9 21.0 9.0 15.0 20.4 17.8 16.6 12.5 15.7 16.9 19.2 11.5 13.7 21.6 20.4 13.9 13.6 9.4 20.8 22.3 14.7 24.6 20.3 16.8 10.8 25.6 51.3 35.6 34.2 32.0 33.1 30.1 24.8 44.7 33.2 46.5 34.2 26.5 40.3 79.0 11.2 41.0 50.7 33.4 61.9 35.9 62.9 45.0 31.7 61.3 20.6 38.9 44.1 23.4 32.0 27.8 40.9 38.3 52.5 36.6 48.5 55.3 64.5 54.7 50.6 32.9 86.9 30.7 35.7 63.6 38.9 49.9 42.6 27.9 37.2 23.8 25.3 27.3 28.5 35.4 44.3 34.6 56.9 27.2 28.5 43.8 32.1 33.8 42.5 40.3 45.2 53.2 41.5 42.8 43.7 36.3 5.6 7.4 8.3 9.3 11.4 9.8 9.9 10.2 7.2 6.9 9.9 10.1 0.7 11.5 9.2 6.4 11.4 6.5 19.0 23.8 21.0 29.0 19.7 21.7 19.8 20.9 20.4 20.4 20.8 25.6 26.6 41.7 27.7 16.0 33.0 15.8 12.1 17.5 19.4 23.7 20.7 19.4 33.4 18.6 24.5 16.5 22.9 35.0 32.9 14.4 54.8 28.3 10.4 15.9 26.9 23.7 23.4 62.7 23.9 28.1 43.9 24.4 20.4 15.3 10.8 31.5 21.4 25.6 25.0 20.2 22.7 17.0 24.4 18.9 12.6 5.7 26.1 20.6 21.4 19.7 31.6 47.3 24.7 15.1 47.7 28.0 13.0 33.4 27.2 18.9 19.9 47.7 17.6 21.9 6.6 29.0 32.2 50.7 24.5 29.9 18.5 37.6 28.0 28.1 23.4 9.1 MTFR1 "CHPPR, FAM54A2, KIAA0009" ENSG00000066855 "Mitochondrial fission regulator 1" Q15390 8 65644734-65771261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 365.5;Late spermatids: 792.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 107.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023152, HPA056120" Uncertain Supported Mitochondria,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Mitochondria Cytosol "HPA023152: AB_1854176, HPA056120: AB_2683043" "prognostic unfavorable (4.06e-4)" "unprognostic (4.58e-2)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (6.56e-3)" "unprognostic (3.93e-2)" "unprognostic (1.66e-1)" "unprognostic (3.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.53e-1)" "unprognostic (5.69e-3)" "unprognostic (5.44e-2)" "unprognostic (6.63e-3)" "unprognostic (1.84e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (8.25e-2)" 9.9 15.2 4.4 6.2 6.1 4.9 10.0 4.7 6.9 9.8 4.6 11.3 12.4 8.4 12.0 10.2 6.3 6.6 7.6 4.3 4.9 31.8 34.9 5.9 4.7 5.2 5.5 6.2 8.8 11.6 3.9 7.6 5.1 7.3 12.0 34.0 8.4 8.5 9.7 8.2 12.5 9.5 4.5 4.0 14.7 19.7 5.3 4.6 11.5 7.3 6.8 8.9 7.6 6.6 34.3 25.1 19.7 22.7 25.7 25.6 15.7 22.3 20.3 26.8 27.9 21.5 34.5 19.0 7.0 21.7 26.6 21.9 44.3 30.0 35.6 6.9 24.0 23.6 16.8 43.1 32.7 6.2 10.9 17.5 31.1 34.7 107.9 15.2 33.1 13.8 32.8 19.0 30.8 30.9 21.1 14.2 20.5 74.9 22.5 10.7 26.9 15.9 32.5 30.2 8.6 12.9 21.9 36.7 29.6 19.6 40.5 13.3 25.8 15.9 22.4 38.8 19.6 18.4 12.9 13.6 19.8 25.0 21.6 1.3 0.8 0.3 0.5 0.6 0.7 0.4 0.7 0.6 0.8 0.3 0.6 0.7 0.2 0.2 0.3 0.5 0.7 0.4 4.4 6.1 4.7 6.9 4.3 4.9 5.2 5.5 5.1 4.5 5.3 6.6 6.8 19.2 9.8 5.9 6.1 16.8 12.3 13.5 10.2 0.0 9.7 4.8 7.4 18.6 12.2 11.0 0.0 25.0 6.9 11.9 56.7 22.6 365.5 7.5 10.0 10.0 4.8 12.6 13.1 24.1 29.0 10.1 14.3 8.2 5.1 9.2 8.9 39.9 9.7 0.0 16.4 12.6 20.3 6.3 7.0 792.9 16.8 6.5 14.2 11.2 3.8 0.0 4.1 18.6 42.4 20.0 9.6 12.0 10.7 20.6 20.0 112.7 16.1 0.0 6.6 7.5 13.1 93.0 35.9 18.4 19.5 39.1 4.5 20.6 15.7 16.6 PDE7A HCP1 ENSG00000205268 "Phosphodiesterase 7A" Q13946 8 65714334-65842322 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 108.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.4;Inhibitory neurons: 111.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 94.9;MOLT-4: 167.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018770, HPA027340" Approved NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB018770: AB_677329, HPA027340: AB_1855127" "unprognostic (2.76e-1)" "unprognostic (2.94e-2)" "unprognostic (1.36e-1)" "unprognostic (1.17e-2)" "unprognostic (2.15e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.64e-4)" "unprognostic (1.44e-2)" "unprognostic (6.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.35e-4)" "unprognostic (3.08e-2)" "unprognostic (1.26e-1)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" 8.5 3.1 5.2 28.5 8.0 26.6 19.8 8.5 7.2 13.4 7.7 7.6 11.4 6.3 14.0 6.6 7.9 11.5 49.3 5.1 5.3 18.8 5.5 19.1 58.8 6.6 5.2 6.0 14.3 3.1 13.4 8.3 5.2 13.7 9.8 14.0 20.8 8.6 63.6 8.2 26.4 5.5 3.9 29.4 13.0 10.3 8.2 108.3 22.9 75.9 43.0 9.9 8.9 11.1 12.5 10.8 47.2 22.2 6.7 5.8 20.0 9.3 7.9 11.5 11.0 12.8 8.1 35.0 2.2 5.8 10.2 13.8 17.5 19.7 12.0 41.3 8.9 25.6 18.5 9.6 3.4 20.3 9.8 8.3 32.0 7.4 22.3 9.9 11.4 84.0 19.1 94.9 7.9 6.8 167.6 23.0 50.3 10.1 4.8 61.8 7.2 9.2 7.8 24.6 22.9 26.5 9.8 4.9 4.8 32.2 26.1 52.2 7.4 15.9 19.6 11.3 7.6 45.6 21.3 60.3 16.1 42.1 8.9 2.5 0.7 5.5 3.4 0.6 5.5 6.5 5.2 3.4 1.5 7.5 11.9 9.2 2.5 2.3 0.2 2.1 4.7 1.8 5.2 8.0 8.5 7.2 5.1 5.3 6.6 5.2 5.2 3.9 8.2 11.1 8.6 19.2 22.7 41.4 95.1 18.1 13.6 8.8 7.4 27.3 23.1 21.8 46.6 20.0 17.3 3.7 56.3 14.1 93.4 3.7 0.0 8.2 32.1 11.8 12.6 7.9 9.6 31.6 102.4 5.3 8.4 17.2 8.2 13.5 9.5 14.2 6.8 4.3 10.4 18.5 111.3 6.5 12.2 17.3 34.9 15.0 7.5 26.2 16.0 48.7 19.7 10.1 47.4 89.0 86.2 6.1 5.6 7.5 56.3 19.4 5.9 21.3 20.3 66.1 0.0 18.4 11.1 10.3 10.9 6.0 18.8 8.6 81.3 6.8 6.5 10.8 DNAJC5B "CSP-beta, MGC26226" ENSG00000147570 "DnaJ heat shock protein family (Hsp40) member C5 beta" Q9UF47 8 66021553-66101245 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 65.4" "Group enriched" "Detected in some" 71 "Early spermatids: 1010.5;Late spermatids: 2756.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 5.7" "Lineage enriched" "Detected in many" 5 "B-cells: 5.7" "Group enriched" "Detected in some" 5 "HDLM-2: 13.9;RPTEC TERT1: 20.4;THP-1: 12.9;U-266/70: 11.3;U-937: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" "unprognostic (1.01e-1)" "unprognostic (7.29e-3)" "unprognostic (7.13e-2)" "unprognostic (2.05e-2)" "unprognostic (1.76e-2)" "unprognostic (4.92e-2)" "unprognostic (7.85e-2)" "unprognostic (7.78e-2)" "unprognostic (2.53e-3)" "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (8.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.80e-1)" "unprognostic (4.42e-2)" "unprognostic (1.88e-1)" "unprognostic (8.84e-2)" 0.3 0.0 0.1 3.0 0.1 0.4 0.6 0.0 0.7 0.3 0.1 1.1 1.1 0.2 0.2 0.3 0.4 0.6 0.4 0.1 0.0 0.3 1.7 6.1 7.7 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.3 1.3 0.0 0.3 0.3 0.7 0.0 1.5 0.1 0.1 1.5 0.7 65.4 0.3 1.1 0.1 3.2 3.8 1.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 12.9 0.0 0.5 0.0 0.0 0.0 11.3 0.0 0.4 0.2 11.1 0.0 0.0 0.6 0.0 0.0 0.5 0.0 5.7 0.0 0.0 1.2 1.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.1 0.0 0.7 0.1 0.0 0.4 0.1 0.2 0.1 0.3 0.6 0.2 0.0 0.0 0.7 7.5 0.1 1.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1010.5 0.0 0.0 1.3 0.0 2.7 0.3 0.0 0.1 0.4 0.5 0.2 1.3 0.0 0.4 0.3 6.8 0.0 1.0 0.0 2.0 10.1 1.0 2756.7 13.4 6.3 1.8 1.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 12.8 1.1 0.3 0.0 0.0 2.3 0.0 26.3 0.4 0.2 18.4 7.2 0.0 0.1 0.0 0.3 0.0 0.0 0.7 TRIM55 "MURF-2, RNF29" ENSG00000147573 "Tripartite motif containing 55" Q9BYV6 8 66126896-66175485 "Predicted intracellular proteins, Predicted membrane proteins" "Muscle protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 61.8;liver: 37.9;skeletal muscle: 29.6;tongue: 33.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 108.9;Endometrial ciliated cells: 64.7;Hepatocytes: 30.4;Skeletal myocytes: 31.0;Spermatocytes: 23.8" "Group enriched" "Detected in some" 10 "liver cancer: 12.3;renal cancer: 5.8" "Region enhanced" "Detected in single" "cerebellum: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "LHCN-M2: 426.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038793, HPA053691" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Golgi apparatus" Cytosol "HPA038793: AB_10673289, HPA053691: AB_2682231" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (5.93e-3)" "unprognostic (4.07e-2)" "unprognostic (6.83e-3)" "unprognostic (3.77e-3)" "unprognostic (8.31e-2)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (5.18e-2)" "unprognostic (2.10e-2)" "unprognostic (9.51e-2)" "unprognostic (1.16e-2)" "unprognostic (1.77e-3)" 1.4 0.0 0.1 0.1 0.0 0.0 0.2 1.5 0.1 0.3 0.0 0.0 0.1 0.1 3.5 0.8 5.3 0.1 61.8 0.0 0.0 4.8 37.9 0.2 0.0 0.1 0.6 0.0 0.2 0.2 0.4 0.0 0.3 0.7 0.1 0.0 1.3 0.2 29.6 0.4 0.1 0.1 0.0 0.1 0.0 7.3 0.0 0.2 0.3 33.7 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.4 0.0 7.2 0.1 0.3 0.1 0.0 0.4 0.5 0.6 0.0 60.5 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.2 426.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.7 1.5 27.6 0.0 2.4 0.0 0.0 0.1 0.0 91.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.1 0.0 0.0 0.1 0.6 0.3 0.0 0.0 0.1 0.1 0.0 2.0 0.0 0.6 0.0 0.1 2.8 0.0 0.0 0.1 0.0 108.9 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 11.8 64.7 0.2 1.2 0.0 0.0 0.2 0.0 0.1 3.8 0.0 3.5 0.0 0.0 0.7 30.4 0.1 0.0 1.5 0.0 0.0 1.3 0.0 6.4 0.9 0.3 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.4 0.2 0.0 0.0 7.4 15.4 0.0 6.6 31.0 2.9 23.8 1.2 0.0 0.0 3.8 0.3 0.0 0.0 0.3 CRH "CRF, CRH1" ENSG00000147571 "Corticotropin releasing hormone" P06850 8 66176376-66178464 "Plasma proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "brain: 137.2" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 160.6" "Cancer enriched" "Detected in some" 28 "urothelial cancer: 34.5" "Region enriched" "Detected in many" 6 "medulla oblongata: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "pons: 25.1" "Secreted to blood" NA NA 10000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "unprognostic (1.62e-1)" "unprognostic (9.68e-2)" "unprognostic (1.00e-1)" "unprognostic (9.55e-2)" "unprognostic (7.22e-3)" 1.5 0.2 5.6 0.0 2.2 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 9.6 0.0 0.0 0.0 0.0 137.2 9.8 0.0 1.6 0.7 0.2 6.6 16.9 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.8 23.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 2.2 0.0 5.4 1.3 9.6 137.2 9.8 16.9 0.2 23.0 1.5 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 31.5 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 160.6 0.0 0.0 0.0 0.1 RRS1 KIAA0112 ENSG00000179041 "Ribosome biogenesis regulator 1 homolog" Q15050 8 66429014-66430733 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055549, HPA060937" Approved Supported Nucleoli NA No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Nucleoli "HPA055549: AB_2682846, HPA060937: AB_2684390" "unprognostic (7.68e-2)" "unprognostic (1.02e-1)" "unprognostic (3.72e-2)" "unprognostic (5.25e-2)" "unprognostic (2.64e-1)" "unprognostic (3.84e-3)" "unprognostic (4.93e-3)" "unprognostic (2.82e-3)" "unprognostic (3.55e-1)" "unprognostic (1.96e-2)" "unprognostic (2.13e-2)" "unprognostic (1.01e-2)" "unprognostic (3.46e-2)" "unprognostic (8.61e-2)" "unprognostic (2.30e-1)" "unprognostic (5.29e-2)" "unprognostic (8.35e-3)" 18.6 14.6 9.8 12.0 9.9 6.5 14.4 9.1 8.9 14.3 10.3 15.5 8.2 19.2 3.8 18.3 16.6 3.6 16.7 8.1 8.5 14.0 14.9 9.8 10.2 14.5 9.9 17.2 41.0 6.0 6.2 5.9 9.9 10.9 5.2 4.4 11.4 6.9 50.0 16.9 12.0 7.4 9.7 13.1 19.0 5.1 11.4 6.5 8.4 14.5 9.5 18.6 13.8 8.6 68.2 83.7 16.9 35.7 17.8 14.3 27.2 41.7 18.3 31.6 23.3 37.7 43.8 91.3 14.2 22.1 44.6 62.5 41.7 47.5 34.7 50.6 70.2 72.8 25.4 67.8 26.3 43.6 37.2 18.9 37.7 34.9 46.1 12.9 20.8 27.5 64.7 37.6 23.3 78.6 87.3 79.2 109.5 76.0 97.2 18.4 21.6 38.3 44.8 54.9 23.0 50.6 20.4 33.4 48.9 17.4 57.6 38.5 36.0 58.5 53.4 49.5 97.5 67.1 64.7 69.8 27.2 68.0 40.4 0.0 13.1 1.0 14.1 17.5 24.8 9.3 17.6 16.5 22.7 8.8 16.1 18.8 0.4 17.3 12.1 10.6 14.2 10.2 9.8 9.9 9.1 8.9 8.1 8.5 14.5 9.9 9.9 9.7 11.4 8.6 8.6 32.1 16.2 3.6 10.0 70.0 42.9 17.9 20.5 9.7 11.8 9.9 29.6 8.6 18.3 12.9 12.5 21.2 13.1 7.1 11.7 28.7 0.2 6.9 16.4 14.6 6.7 13.2 1.5 28.3 23.1 13.6 11.7 8.9 7.6 11.5 12.5 14.8 20.3 6.7 2.8 13.4 8.2 12.2 11.9 1.0 19.0 9.8 23.2 0.0 15.6 8.6 26.8 0.5 2.0 22.1 9.5 17.3 8.7 37.9 3.4 30.0 9.6 13.1 19.7 28.9 21.6 6.2 16.8 19.6 59.8 38.6 20.1 17.9 22.1 30.6 AC009879.2 ENSG00000285655 "Novel protein" 8 66430185-66445324 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.6 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 VXN "C8orf46, MGC33510" ENSG00000169085 Vexin Q8TAG6 8 66493520-66518524 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 123.8" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.1;Proximal tubular cells: 3.4;Syncytiotrophoblasts: 1.0" "Cancer enriched" "Detected in many" 6 "glioma: 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 4.5;GAMG: 5.4;HBF TERT88: 3.9;LHCN-M2: 4.4;T-47d: 5.8;WM-115: 4.5" "Group enriched" "Detected in all" 8 "amygdala: 159.7;basal ganglia: 78.9;cerebral cortex: 298.2;hippocampal formation: 219.3;white matter: 199.5" "Low region specificity" "Detected in all" HPA075134 Approved "Nuclear speckles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" "HPA075134: AB_2686736" "unprognostic (6.87e-2)" "unprognostic (7.85e-2)" "unprognostic (2.01e-1)" "unprognostic (8.36e-4)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (7.53e-4)" "unprognostic (7.87e-3)" "unprognostic (1.45e-1)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "unprognostic (1.82e-1)" "unprognostic (6.36e-3)" "unprognostic (3.53e-4)" "unprognostic (1.86e-1)" "unprognostic (4.98e-2)" "unprognostic (2.91e-2)" 0.3 0.5 61.0 0.3 72.1 0.0 0.5 52.0 87.2 0.9 21.7 1.8 0.0 0.7 1.3 0.0 0.5 0.2 0.3 123.8 47.4 0.6 1.4 0.3 0.0 53.1 56.2 0.3 0.6 0.4 0.4 0.0 56.0 1.5 0.3 0.2 0.1 5.4 0.5 0.2 0.5 1.1 53.4 0.1 1.2 0.3 53.7 0.0 0.2 0.0 0.3 0.3 0.4 84.5 2.7 0.1 1.0 1.3 0.1 0.1 0.0 0.2 0.4 1.2 1.3 0.1 4.5 0.0 0.1 2.9 5.4 0.1 0.0 0.0 3.9 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 0.1 4.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 1.9 0.1 0.2 0.0 0.1 0.1 3.0 0.1 5.8 0.0 0.0 0.4 0.9 0.0 1.9 2.0 1.1 0.0 1.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.0 72.1 52.0 87.2 123.8 47.4 53.1 56.2 56.0 53.4 53.7 84.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.6 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.4 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.3 0.0 0.0 MYBL1 "A-myb, AMYB" ENSG00000185697 "MYB proto-oncogene like 1" P10243 8 66562175-66614247 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.1;testis: 11.8" "Group enriched" "Detected in many" 6 "dendritic cells: 127.3;NK-cells: 107.1;Plasma cells: 40.2;Spermatocytes: 35.8;T-cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.9;MAIT T-cell: 1.3" "Lineage enhanced" "Detected in single" "T-cells: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 82.5;BJ hTERT+ SV40 Large T+ RasG12V: 69.4;Daudi: 87.7;HBF TERT88: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA008791 Uncertain Supported Nucleoplasm NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA008791: AB_1078540" "unprognostic (1.11e-1)" "unprognostic (2.47e-2)" "unprognostic (2.57e-1)" "unprognostic (7.23e-4)" "unprognostic (2.26e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.38e-1)" "unprognostic (1.25e-1)" "unprognostic (3.78e-2)" "unprognostic (1.13e-2)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.03e-8)" "unprognostic (2.04e-1)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (5.87e-2)" 1.0 0.7 1.1 6.1 2.2 2.5 1.7 2.0 1.7 0.7 0.3 1.0 1.3 1.1 0.5 0.7 0.8 2.3 3.4 1.0 1.3 0.4 2.0 2.3 20.1 2.9 1.7 0.6 0.2 0.4 0.4 0.9 3.2 1.2 1.4 5.9 0.5 1.6 0.9 1.2 1.9 2.3 1.9 7.6 1.3 11.8 1.6 2.5 0.6 0.8 16.1 1.1 0.8 3.7 35.4 11.9 3.7 10.1 1.0 2.1 2.6 47.7 21.8 82.5 69.4 1.6 34.9 87.7 4.2 40.4 31.0 10.0 3.5 4.0 113.0 10.6 5.5 1.8 13.4 1.6 0.2 0.8 3.4 0.7 0.4 22.7 19.0 14.8 2.7 6.4 0.4 28.3 51.0 3.1 5.8 1.3 2.8 3.3 15.8 1.9 14.1 2.2 19.4 1.2 8.2 3.3 8.4 3.0 8.6 5.6 50.6 2.3 14.5 49.4 11.3 11.1 44.2 8.2 12.1 25.7 13.0 5.3 20.0 0.0 0.0 0.0 1.9 0.0 1.3 0.0 0.3 0.8 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.1 1.1 2.2 2.0 1.7 1.0 1.3 2.9 1.7 3.2 1.9 1.6 3.7 3.0 0.0 2.3 3.3 4.0 1.8 0.4 0.3 1.8 10.4 4.7 6.6 9.1 2.8 0.1 0.0 2.1 2.0 127.3 0.5 0.0 0.5 3.9 0.8 2.4 1.7 0.0 6.6 3.9 0.0 0.7 2.7 3.1 1.4 0.0 5.6 4.2 0.9 0.7 5.0 2.7 0.4 0.0 1.6 3.2 4.2 0.9 5.1 1.8 8.4 1.6 10.3 107.1 5.5 12.4 0.2 1.1 0.0 40.2 0.3 0.0 0.5 1.5 9.1 0.0 2.5 4.5 35.8 6.8 3.2 0.4 1.5 89.1 1.4 0.8 0.3 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 4.6 3.6 3.2 6.0 3.6 20.2 4.8 4.1 5.1 3.7 1.8 4.4 3.8 3.0 4.5 3.5 2.9 3.7 2.9 4.1 4.7 4.4 7.0 4.1 8.6 4.0 3.6 3.9 4.0 5.6 1.6 4.4 4.4 3.6 4.1 4.5 4.2 3.1 5.3 3.3 3.6 3.3 3.4 8.8 4.5 5.7 5.0 5.3 4.2 5.3 7.7 4.1 2.4 4.3 8.5 7.6 3.8 5.1 11.5 8.1 3.7 6.7 6.7 5.0 5.8 4.5 7.8 11.5 1.9 9.0 6.2 7.4 6.2 5.6 7.2 8.6 4.5 12.8 7.5 5.6 6.9 4.3 13.2 8.7 8.1 5.5 9.9 6.1 5.5 6.1 8.8 10.8 7.5 4.1 9.4 7.4 7.3 7.1 5.2 5.9 6.0 5.8 7.3 6.6 2.2 4.3 5.2 7.8 6.0 4.8 8.0 7.0 11.1 6.6 4.9 5.9 4.5 9.5 5.0 11.9 6.6 6.0 5.1 10.0 2.7 5.9 3.4 4.3 2.8 1.7 2.1 2.5 2.9 2.2 1.7 2.2 9.7 2.4 8.3 1.1 2.8 1.7 3.2 3.6 4.1 5.1 4.1 4.7 4.0 3.6 4.4 3.4 5.0 4.3 18.6 19.2 15.2 9.8 18.5 17.0 9.3 10.3 12.5 11.0 12.6 9.4 20.3 11.5 12.8 7.3 22.9 10.4 38.9 18.4 3.9 10.2 7.5 16.7 17.1 14.2 6.0 23.4 17.6 13.6 5.5 15.0 15.3 16.4 19.0 12.4 17.2 22.9 14.9 11.8 18.1 15.5 8.2 47.3 20.4 5.2 8.1 25.6 10.6 14.0 28.6 11.9 39.1 13.6 21.1 13.0 16.6 15.8 21.8 14.2 14.7 12.8 18.6 12.1 6.6 21.7 20.2 32.9 16.6 16.3 20.6 9.9 28.6 11.8 13.2 16.9 C8orf44-SGK3 ENSG00000288602 "C8orf44-SGK3 readthrough" 8 66667596-66860472 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 17.3;Excitatory neurons: 23.5;Inhibitory neurons: 17.5;Microglial cells: 11.2;Oligodendrocyte precursor cells: 15.6;Oligodendrocytes: 18.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 31.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006699, HPA027146" Approved Uncertain Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" 4.1 3.1 5.2 3.1 5.5 6.1 6.3 5.3 7.2 4.5 3.5 3.5 2.8 5.6 11.5 2.1 7.3 3.7 4.4 5.1 6.3 4.2 3.1 3.4 5.7 4.6 4.8 7.9 2.2 2.9 3.8 4.7 5.1 5.8 9.1 4.2 6.1 4.1 6.9 2.6 4.9 3.9 5.1 4.3 6.6 4.8 5.7 7.6 3.7 5.4 2.6 7.5 6.9 2.4 3.5 2.6 5.8 7.0 1.7 2.3 4.3 5.2 5.8 2.8 8.7 9.8 1.3 5.3 4.1 4.4 5.5 3.1 8.2 8.5 8.3 9.3 7.2 5.5 4.6 5.3 6.0 9.2 9.1 3.3 7.3 9.0 5.3 10.7 9.7 5.6 4.8 2.1 4.6 3.7 3.5 6.6 3.8 3.7 2.4 2.4 5.0 2.0 3.4 3.8 2.9 1.3 3.9 5.3 7.0 3.5 5.1 2.6 2.5 2.2 2.2 5.7 3.8 4.8 4.7 6.0 1.4 31.0 9.8 6.2 4.0 4.1 4.9 7.6 4.5 5.1 7.2 6.1 7.0 5.0 6.9 5.2 2.7 6.9 7.0 4.2 5.2 5.5 5.3 7.2 5.1 6.3 4.6 4.8 4.7 3.9 4.8 7.5 0.0 0.0 0.0 17.3 0.9 0.0 0.0 0.1 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 23.5 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 11.2 0.1 0.5 0.0 15.6 18.0 0.0 1.1 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 1.4 0.1 0.0 0.6 0.0 0.0 0.0 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 MCMDC2 "C8orf45, FLJ25692" ENSG00000178460 "Minichromosome maintenance domain containing 2" Q4G0Z9 8 66870749-66922048 "Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.9" "Group enriched" "Detected in many" 4 "Early spermatids: 50.7;Spermatocytes: 65.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-MEL-30: 12.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA026522 Approved "Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Actin filaments" "HPA026522: AB_10603453" "unprognostic (6.97e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.54e-2)" "unprognostic (2.38e-2)" "unprognostic (3.03e-1)" "unprognostic (1.42e-1)" "unprognostic (9.46e-2)" "unprognostic (9.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.79e-3)" "unprognostic (7.87e-2)" "unprognostic (3.06e-2)" "unprognostic (8.49e-2)" "unprognostic (2.31e-5)" 1.1 1.8 0.5 1.3 1.1 4.1 0.7 2.0 0.9 0.4 0.0 0.7 1.4 1.2 0.9 1.6 1.0 1.1 2.5 0.4 0.7 1.0 0.6 0.8 2.8 1.0 0.8 3.0 1.5 1.1 0.9 0.5 0.9 0.9 0.7 4.4 1.4 0.3 5.9 2.2 1.4 0.1 0.7 1.2 1.0 11.9 0.7 0.2 1.4 1.4 0.2 0.7 0.3 1.9 2.7 5.6 2.8 3.4 0.4 1.3 1.5 2.5 0.4 0.2 0.2 4.8 3.5 4.1 1.0 0.2 1.5 2.3 0.0 0.1 0.8 2.1 6.9 5.1 8.9 5.8 0.6 2.3 2.7 0.9 0.8 0.1 0.0 4.1 0.2 3.9 3.2 3.8 1.1 5.3 5.8 7.2 3.5 4.5 5.1 2.0 1.0 1.8 0.5 4.1 1.9 3.5 0.8 1.0 12.3 1.6 3.5 6.0 1.2 1.9 2.7 3.2 3.1 3.1 1.8 3.9 2.1 4.8 2.0 0.9 0.5 0.2 0.9 0.4 1.2 1.0 1.4 1.1 1.1 1.0 1.6 1.4 0.2 1.3 0.3 1.2 1.1 0.5 0.5 1.1 2.0 0.9 0.4 0.7 1.0 0.8 0.9 0.7 0.7 1.9 0.4 0.0 0.5 12.4 0.7 0.4 0.5 0.4 1.2 2.0 1.8 1.3 2.7 0.0 0.4 1.8 6.2 1.2 0.2 0.4 0.0 0.2 50.7 4.9 0.9 0.7 0.0 0.0 6.2 0.2 0.6 0.5 2.6 0.6 0.0 0.7 0.4 0.0 0.5 1.7 5.1 0.8 0.0 1.6 0.3 12.4 1.8 0.4 1.8 0.0 0.0 2.0 1.0 6.0 12.0 0.1 0.3 0.7 0.2 0.2 0.2 0.8 3.6 2.4 0.0 1.0 0.6 65.7 11.1 1.3 1.0 0.0 0.7 1.2 1.2 0.6 TCF24 bHLHa25 ENSG00000261787 "Transcription factor 24" Q7RTU0 8 66946501-66962591 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 1.0;kidney: 1.1;testis: 1.5" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 5.1;Spermatocytes: 4.7;Spermatogonia: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.2;HEK 293: 5.5;HMC-1: 4.7;K-562: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "unprognostic (1.07e-1)" "unprognostic (9.14e-3)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (8.30e-2)" "unprognostic (1.20e-1)" "unprognostic (2.74e-1)" "unprognostic (2.25e-1)" "unprognostic (9.38e-3)" "unprognostic (9.36e-2)" "unprognostic (1.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.14e-1)" "unprognostic (1.09e-1)" 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 1.0 0.3 0.1 1.1 0.0 0.0 0.0 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.0 0.0 2.2 0.0 0.0 0.0 5.5 0.2 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.4 0.0 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.1 0.7 0.7 0.6 0.5 0.3 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP1R42 "dtr, LRRC67, TLLR" ENSG00000178125 "Protein phosphatase 1 regulatory subunit 42" Q7Z4L9 8 66964099-67056604 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 4.9;testis: 8.7" "Group enriched" "Detected in many" 5 "Early spermatids: 68.1;Endometrial ciliated cells: 79.3;Respiratory ciliated cells: 127.2;Spermatocytes: 111.8" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024313, HPA027983, HPA028628" Uncertain NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 49: Ciliated cells - Cilium organization" "HPA024313: AB_1853053, HPA027983: AB_10599300, HPA028628: AB_2250064" "unprognostic (8.03e-3)" "unprognostic (5.45e-2)" "unprognostic (4.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (1.99e-2)" "unprognostic (1.03e-1)" "unprognostic (3.61e-3)" "unprognostic (6.86e-2)" "unprognostic (8.58e-3)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (8.07e-2)" "unprognostic (2.33e-1)" 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.2 0.4 0.1 1.4 0.0 0.0 0.1 0.3 0.0 4.9 0.0 0.0 0.4 0.4 0.2 0.0 0.3 0.0 1.4 1.2 0.0 0.0 0.3 0.2 0.0 0.9 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 8.7 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.4 0.4 1.4 1.2 0.9 0.9 0.5 0.6 0.0 0.0 1.1 11.8 0.0 0.0 0.0 6.0 0.0 0.1 0.7 1.0 0.9 0.0 10.8 5.5 0.0 0.0 0.0 0.0 3.9 0.5 68.1 79.3 0.7 0.2 0.0 0.0 3.2 0.0 0.0 0.6 0.0 1.0 0.0 0.3 0.0 0.0 0.0 1.7 2.8 0.0 6.1 0.0 0.0 16.5 0.6 0.3 0.0 1.0 0.0 3.6 0.0 3.5 2.9 0.1 0.0 1.9 0.0 0.0 0.0 1.9 127.2 3.5 6.6 0.0 1.4 111.8 3.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 COPS5 "CSN5, JAB1, MOV-34, SGN5" ENSG00000121022 "COP9 signalosome subunit 5" Q92905 8 67043079-67083783 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 347.5;Late spermatids: 427.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004242, HPA004845, HPA051531" Supported Enhanced Nucleoplasm NA NA 37000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "CAB004242: AB_627835, HPA004845: AB_1078557, HPA051531: AB_2681522" "unprognostic (1.90e-3)" "unprognostic (1.35e-1)" "unprognostic (1.61e-1)" "unprognostic (2.85e-3)" "unprognostic (2.53e-1)" "unprognostic (4.16e-2)" "unprognostic (2.04e-3)" "unprognostic (1.39e-1)" "unprognostic (2.15e-2)" "unprognostic (4.48e-2)" "unprognostic (4.74e-3)" "unprognostic (1.96e-2)" "unprognostic (1.90e-3)" "unprognostic (2.88e-2)" "unprognostic (1.76e-1)" "unprognostic (2.58e-1)" "unprognostic (1.18e-2)" 43.5 43.8 52.1 33.3 54.2 39.4 45.2 58.3 62.6 34.2 52.0 45.5 45.6 34.0 43.6 42.2 35.6 31.6 100.0 53.2 57.1 56.3 71.0 33.1 40.9 55.1 53.3 33.4 43.0 58.5 31.1 50.9 56.8 36.4 51.6 39.7 42.3 36.6 125.2 36.0 47.8 47.6 57.4 33.4 37.6 58.7 56.2 52.6 37.8 134.9 48.7 42.2 30.0 59.7 104.0 97.8 79.6 74.4 83.1 88.3 63.3 89.0 74.0 121.2 108.9 62.6 125.4 96.5 39.9 93.6 86.8 84.1 109.2 98.9 134.0 92.4 92.1 135.9 95.2 87.3 82.2 86.3 79.1 81.0 126.2 99.1 132.6 95.2 121.2 100.3 163.0 64.6 111.8 96.5 154.3 157.6 107.1 217.2 108.6 97.2 56.7 76.4 131.3 91.6 48.6 66.7 51.0 98.4 91.6 71.2 160.9 90.8 89.9 60.1 74.9 74.7 70.3 81.4 108.5 127.7 89.1 97.6 84.1 65.8 52.0 64.5 35.8 55.7 37.2 36.8 34.6 39.9 63.9 33.7 36.1 32.4 38.3 51.9 56.6 34.0 53.2 43.8 52.1 54.2 58.3 62.6 53.2 57.1 55.1 53.3 56.8 57.4 56.2 59.7 55.0 22.4 26.0 19.2 40.6 49.3 45.1 102.6 28.5 36.4 43.7 51.8 119.9 58.6 61.2 31.3 33.3 143.8 58.0 38.1 88.0 73.4 347.5 44.6 38.2 46.4 34.2 69.2 21.5 60.0 101.4 45.2 25.5 37.1 36.1 50.9 34.2 35.5 79.3 25.2 21.5 41.5 59.0 31.7 28.5 427.2 43.2 40.2 28.4 10.3 59.9 62.0 56.7 18.6 32.4 50.1 48.6 51.1 46.6 54.0 87.8 81.9 46.1 53.0 32.9 49.1 87.8 123.4 49.6 42.9 47.5 127.8 42.3 72.5 55.4 50.6 CSPP1 "CSPP, CSPP-L, FLJ22490, JBTS21" ENSG00000104218 "Centrosome and spindle pole associated protein 1" Q1MSJ5 8 67062417-67196778 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 165.8;Endometrial ciliated cells: 177.6;Respiratory ciliated cells: 202.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056174 Supported "Centriolar satellite,Centrosome" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 49: Ciliated cells - Cilium organization" "Centriolar satellite, Centrosome" "HPA056174: " "unprognostic (1.44e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" "unprognostic (4.70e-1)" "unprognostic (2.59e-2)" "unprognostic (5.24e-3)" "unprognostic (3.89e-2)" "unprognostic (7.85e-2)" "unprognostic (2.11e-1)" "unprognostic (1.30e-1)" "unprognostic (3.61e-2)" "unprognostic (9.29e-2)" "unprognostic (3.40e-1)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.98e-4)" "unprognostic (2.93e-1)" 4.1 2.9 0.8 1.5 0.7 0.8 4.4 1.5 1.3 5.4 1.4 4.1 2.2 4.3 1.8 3.4 8.4 3.1 3.7 0.6 0.6 5.5 5.4 5.8 1.4 1.0 1.1 5.6 6.0 4.3 3.3 6.0 0.9 3.6 2.8 2.1 3.6 1.6 13.5 3.6 4.0 2.6 0.7 3.3 4.4 12.8 1.2 3.9 4.6 2.8 2.0 4.1 4.1 1.0 5.7 4.9 4.6 5.9 5.3 5.6 4.9 4.9 6.3 6.5 6.9 4.6 6.6 6.5 1.1 3.3 6.9 4.4 11.4 3.4 9.1 3.6 7.2 9.3 2.3 2.9 4.5 7.7 4.0 4.4 2.9 4.2 8.2 3.9 4.1 7.9 16.1 3.0 5.9 2.1 19.1 3.2 6.1 14.8 4.9 10.4 6.9 5.4 4.9 2.6 3.0 3.0 3.1 5.9 4.7 6.3 10.8 4.4 4.1 4.7 4.7 2.1 4.2 4.6 3.2 8.6 3.6 6.1 5.6 0.6 0.1 0.2 0.5 1.0 0.6 0.5 0.4 0.5 0.4 0.8 0.8 0.3 0.0 0.3 0.3 0.4 1.0 0.3 0.8 0.7 1.5 1.3 0.6 0.6 1.0 1.1 0.9 0.7 1.2 1.0 20.9 25.6 11.8 63.3 15.0 21.2 11.1 7.6 16.5 20.5 19.4 18.7 39.8 31.5 32.4 7.3 73.0 21.8 23.6 9.6 3.9 14.8 165.8 177.6 29.1 16.6 11.4 16.6 117.5 9.7 13.7 20.2 11.2 27.7 26.0 36.8 12.1 9.3 7.4 21.9 116.1 9.6 8.2 7.2 9.4 91.0 21.5 12.5 7.2 61.8 12.9 13.6 17.5 89.0 98.1 9.8 5.3 19.5 19.4 11.0 10.8 23.0 202.3 133.2 26.3 31.7 20.4 121.6 60.1 15.3 16.2 18.5 15.9 14.6 13.6 6.9 ARFGEF1 "ARFGEP1, BIG1, DKFZP434L057, p200" ENSG00000066777 "ADP ribosylation factor guanine nucleotide exchange factor 1" Q9Y6D6 8 67173511-67343781 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023399, HPA023822" Supported Supported Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA023399: AB_1844981, HPA023822: AB_1844982" "prognostic unfavorable (8.76e-4)" "unprognostic (1.62e-1)" "unprognostic (4.60e-2)" "unprognostic (1.01e-2)" "unprognostic (1.11e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-2)" "unprognostic (4.52e-1)" "unprognostic (5.38e-2)" "unprognostic (4.67e-2)" "unprognostic (2.13e-3)" "unprognostic (1.31e-1)" "prognostic favorable (2.48e-4)" "unprognostic (1.13e-1)" "unprognostic (2.84e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" 11.4 10.3 5.6 14.6 5.3 27.5 13.6 8.2 6.8 14.2 10.1 19.2 16.9 10.5 11.0 15.2 11.8 12.5 9.6 4.6 5.5 22.8 15.2 13.8 15.4 6.2 6.5 10.3 17.5 28.0 5.4 14.4 6.7 13.0 17.2 36.5 14.8 12.1 12.8 13.7 17.5 10.8 5.2 13.8 19.6 28.3 6.4 22.2 22.4 14.0 17.2 19.7 7.9 7.3 31.8 20.4 19.3 7.3 21.9 29.8 22.5 21.4 24.3 21.7 22.0 12.6 30.0 23.9 8.9 27.6 26.2 22.2 23.5 30.4 26.6 28.3 16.0 40.2 12.0 13.5 18.6 20.9 37.3 18.4 21.6 19.2 31.8 22.3 31.5 24.6 24.5 25.3 25.5 7.2 48.1 9.7 42.5 34.5 18.5 22.4 13.9 4.8 35.8 58.2 7.6 14.9 14.1 33.9 19.5 29.5 58.5 18.3 38.6 14.4 19.3 19.5 16.4 20.4 22.6 17.5 23.6 20.8 14.2 6.1 1.6 4.3 2.8 2.3 3.6 1.2 1.8 2.3 1.6 1.3 3.0 2.6 5.1 2.5 0.9 2.2 3.9 0.9 5.6 5.3 8.2 6.8 4.6 5.5 6.2 6.5 6.7 5.2 6.4 7.3 38.5 44.8 23.1 73.1 32.7 23.7 34.0 23.8 19.9 36.8 32.7 18.9 33.1 18.6 31.9 38.6 139.7 20.0 47.0 43.2 11.7 29.7 25.4 42.5 34.7 28.5 29.4 16.2 119.0 25.6 15.4 22.9 57.6 53.0 15.2 40.0 23.2 19.6 15.8 43.7 146.3 27.9 14.2 31.3 20.4 36.0 40.0 35.2 17.8 105.9 47.1 22.9 46.4 151.8 126.6 40.1 25.7 30.1 29.8 38.2 30.8 24.7 33.9 100.8 6.6 23.6 26.5 69.4 50.7 26.0 29.5 24.9 42.4 32.1 28.0 60.4 CPA6 CPAH ENSG00000165078 "Carboxypeptidase A6" Q8N4T0 8 67422038-67746378 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.3;prostate: 2.7;retina: 2.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 31.7;Early spermatids: 21.7;Microglial cells: 12.2;Muller glia cells: 22.5;Pancreatic endocrine cells: 21.5;Paneth cells: 12.8;Prostatic glandular cells: 11.3;Urothelial cells: 36.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 2.5;EFO-21: 1.5;Hep G2: 3.4;OE19: 1.5" "Region enriched" "Detected in some" 9 "olfactory bulb: 12.6" "Low region specificity" "Detected in all" "Secreted to extracellular matrix" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "unprognostic (2.85e-2)" "unprognostic (1.95e-1)" "unprognostic (1.72e-2)" "unprognostic (1.14e-1)" "unprognostic (2.58e-1)" "unprognostic (2.24e-1)" "unprognostic (2.08e-1)" "unprognostic (2.88e-1)" "unprognostic (9.35e-2)" "unprognostic (1.65e-1)" "unprognostic (5.23e-2)" "unprognostic (6.99e-2)" "unprognostic (3.57e-4)" "unprognostic (9.61e-5)" "unprognostic (1.75e-1)" "unprognostic (9.09e-2)" "unprognostic (1.41e-2)" 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.3 2.2 0.0 0.2 0.0 0.0 0.2 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 31.7 0.0 5.7 0.2 0.1 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.0 21.7 0.1 0.0 0.1 2.4 0.0 1.6 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.7 1.3 2.2 0.0 0.0 0.0 3.2 1.8 0.2 0.0 12.2 0.1 22.5 0.0 3.0 1.3 21.5 12.8 0.0 0.0 11.3 0.0 0.0 0.0 1.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.6 0.0 5.7 36.6 PREX2 "DEP.2, DEPDC2, FLJ12987, P-REX2, PPP1R129" ENSG00000046889 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2" Q70Z35 8 67952046-68237032 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.1" "Cell type enhanced" "Detected in many" "Astrocytes: 717.6;Microglial cells: 120.9;Oligodendrocyte precursor cells: 422.2;Oligodendrocytes: 222.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.0;HUVEC TERT2: 19.2;JURKAT: 8.3;NTERA-2: 12.1;RH-30: 5.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015234, HPA075956" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum" "HPA015234: AB_1847604, HPA075956: AB_2686769" "unprognostic (2.25e-1)" "unprognostic (3.32e-2)" "unprognostic (1.30e-2)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.37e-2)" "unprognostic (4.19e-1)" "unprognostic (8.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (2.53e-2)" "unprognostic (8.77e-2)" "prognostic unfavorable (1.61e-7)" "unprognostic (8.30e-3)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (6.64e-2)" 9.3 1.0 11.5 1.2 15.2 0.1 5.5 15.8 9.4 4.4 0.1 2.6 1.7 2.5 1.7 1.7 5.5 3.2 3.8 12.5 10.1 1.6 1.2 4.4 0.8 16.1 13.5 1.9 1.1 1.1 1.9 8.1 13.2 2.5 1.7 3.6 1.3 2.2 2.2 1.7 1.8 2.5 12.6 1.3 1.6 0.9 13.4 0.9 7.3 5.0 1.0 2.7 2.6 14.1 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 8.3 0.0 0.0 0.0 0.0 3.0 0.0 12.1 0.0 0.0 0.0 5.5 0.0 0.7 0.0 3.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.3 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 15.2 15.8 9.4 12.5 10.1 16.1 13.5 13.2 12.6 13.4 14.1 103.3 3.2 5.0 717.6 0.3 4.0 3.6 0.0 0.0 21.8 0.6 0.8 6.1 1.5 3.1 1.8 2.1 0.0 0.6 0.0 0.0 0.2 52.7 15.2 3.2 57.0 0.0 0.0 2.2 0.0 0.0 19.7 0.0 26.2 1.3 0.0 56.4 0.7 0.1 5.0 81.3 0.0 0.0 2.7 5.1 9.6 11.1 0.8 8.8 120.9 0.0 65.8 0.0 422.2 222.1 0.0 0.0 10.5 1.3 0.8 0.0 0.0 0.7 4.1 26.3 3.9 13.8 0.9 1.2 0.5 2.6 0.0 1.1 0.2 0.0 1.6 C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.2;fallopian tube: 9.1;parathyroid gland: 7.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 396.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.3;HEK 293: 2.3;LHCN-M2: 2.7;RH-30: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044420, HPA053065" Uncertain Supported "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: AB_10963791, HPA053065: AB_2682030" "unprognostic (1.75e-1)" "unprognostic (2.20e-1)" "unprognostic (3.30e-2)" "unprognostic (5.59e-3)" "unprognostic (3.07e-1)" "unprognostic (2.85e-2)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.80e-1)" "unprognostic (1.74e-1)" "unprognostic (8.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.80e-4)" "unprognostic (5.21e-2)" "unprognostic (8.87e-2)" "unprognostic (2.84e-4)" "unprognostic (1.33e-1)" 2.7 0.3 4.0 0.2 5.4 0.5 0.7 3.6 3.9 2.1 2.0 0.2 0.2 0.6 0.6 1.0 9.1 0.6 0.7 6.2 3.8 0.4 0.2 2.5 0.2 6.4 10.2 0.4 1.1 7.4 1.7 0.3 4.6 2.1 0.3 1.0 0.6 1.0 0.3 0.9 0.2 0.1 4.0 0.2 0.8 0.7 6.7 0.8 0.4 0.9 0.2 0.4 0.2 6.1 0.1 0.0 0.3 0.1 0.6 1.0 0.1 0.9 2.3 0.3 0.3 0.1 0.2 0.1 0.3 0.5 0.1 0.1 0.1 0.3 0.1 0.0 2.3 0.3 0.5 0.2 0.1 0.0 0.2 0.1 0.3 0.4 0.8 0.1 0.0 0.3 0.1 0.4 2.7 0.3 0.0 0.2 1.0 0.0 0.0 0.1 2.7 0.0 0.2 0.2 0.5 0.0 0.1 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.2 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.4 0.5 0.1 0.2 0.2 0.0 0.2 0.2 0.2 0.2 0.0 0.3 0.2 0.3 0.5 0.2 0.1 0.4 0.1 0.1 4.0 5.4 3.6 3.9 6.2 3.8 6.4 10.2 4.6 4.0 6.7 6.1 0.2 16.0 18.7 9.4 0.0 1.7 0.8 0.2 0.0 1.5 0.2 0.0 1.2 0.0 3.9 0.0 0.0 0.5 0.1 0.0 0.0 0.3 0.5 26.4 0.7 0.5 0.0 0.0 79.2 0.0 0.3 1.9 0.0 4.3 1.3 0.1 0.0 0.0 0.3 0.0 396.6 0.1 0.0 0.0 1.2 1.3 0.3 0.4 1.8 3.7 0.1 0.0 0.0 9.5 10.1 0.5 0.0 0.4 0.0 0.8 0.0 0.0 20.8 0.7 0.0 0.6 1.7 0.6 0.4 0.1 0.9 0.4 0.4 0.2 0.0 0.4 SULF1 "hSulf-1, KIAA1077, SULF-1" ENSG00000137573 "Sulfatase 1" Q8IWU6 8 69466624-69660915 "Predicted intracellular proteins" Apoptosis Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 180.3" "Cell type enhanced" "Detected in many" "Early spermatids: 214.2;Fibroblasts: 52.8;Inhibitory neurons: 63.0;Late spermatids: 101.4;Muller glia cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 315.4;BJ hTERT+: 420.2;fHDF/TERT166: 520.0;U-2197: 126.1;WM-115: 175.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054728 Supported "Intracellular and membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" "HPA054728: AB_2682586" "unprognostic (2.89e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-2)" "unprognostic (7.62e-2)" "unprognostic (3.77e-2)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (1.45e-1)" "unprognostic (3.69e-2)" "unprognostic (7.82e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (8.91e-3)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.69e-2)" 24.1 2.6 8.1 24.4 6.4 0.0 8.0 2.2 2.7 14.5 180.3 36.4 10.0 28.7 14.2 18.3 11.3 30.6 14.2 6.4 7.4 9.9 1.8 9.7 6.3 1.9 18.2 14.2 3.5 1.4 9.7 4.2 5.8 50.8 20.6 60.0 4.3 41.9 2.2 2.6 14.1 72.6 3.4 2.2 4.0 2.2 18.6 2.2 19.9 11.2 4.8 32.1 9.5 3.0 0.0 0.0 57.3 0.0 6.2 27.3 0.4 315.4 420.2 10.9 1.7 0.0 1.2 0.5 0.2 520.0 0.0 0.4 0.8 0.5 2.1 0.0 1.1 0.0 1.0 0.0 1.5 0.1 0.5 35.6 3.7 18.2 6.7 15.2 1.4 0.0 0.0 0.6 8.5 1.3 0.0 0.0 6.5 0.0 0.4 0.0 23.2 0.9 0.0 0.0 1.1 0.0 0.0 0.5 0.0 22.6 76.7 0.0 0.0 29.0 0.8 126.1 0.0 0.1 0.0 0.1 0.1 0.1 175.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 6.4 2.2 2.7 6.4 7.4 1.9 18.2 5.8 3.4 18.6 3.0 10.6 9.6 6.2 3.9 0.1 0.9 2.7 7.8 26.2 1.8 1.3 13.7 4.3 2.8 13.5 5.5 0.0 0.3 0.0 0.0 0.0 0.3 214.2 1.0 30.5 13.5 1.2 2.7 9.6 0.0 0.0 52.8 0.0 1.0 0.0 0.1 15.4 0.5 0.3 0.0 63.0 0.3 0.0 0.6 1.3 101.4 6.5 0.8 0.0 1.0 0.0 162.8 0.0 3.5 0.6 0.7 0.1 1.9 0.0 1.4 0.0 0.1 5.5 6.5 0.0 5.2 42.4 1.6 1.4 2.5 0.3 0.3 0.3 0.1 0.0 0.4 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 PRDM14 ENSG00000147596 "PR/SET domain 14" Q9GZV8 8 70051651-70071693 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 658 "testis cancer: 34.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 93 "NTERA-2: 49.4;SuSa: 13.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019094, HPA057070" Uncertain Uncertain Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "HPA019094: AB_1855686, HPA057070: AB_2683327" "unprognostic (5.86e-2)" "unprognostic (9.32e-2)" "unprognostic (6.14e-3)" "unprognostic (1.37e-2)" "unprognostic (8.62e-2)" 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.6 0.4 0.0 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 49.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 13.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.4 0.3 0.2 0.0 0.2 0.1 0.0 0.0 0.2 0.2 0.6 0.4 0.1 0.0 0.3 0.1 0.3 0.0 0.2 0.8 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 NCOA2 "bHLHe75, GRIP1, KAT13C, NCoA-2, TIF2" ENSG00000140396 "Nuclear receptor coactivator 2" Q15596 8 70109782-70403808 "Cancer-related genes, Disease related genes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 161.6;Excitatory neurons: 158.9;Inhibitory neurons: 314.8;Microglial cells: 233.3;Oligodendrocyte precursor cells: 249.8;Oligodendrocytes: 186.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060243 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear bodies" "HPA060243: AB_2684229" "unprognostic (9.79e-3)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (4.94e-3)" "unprognostic (1.91e-2)" "unprognostic (2.18e-3)" "unprognostic (1.30e-1)" "unprognostic (6.77e-2)" "unprognostic (2.06e-1)" "unprognostic (7.00e-2)" "unprognostic (2.20e-2)" "unprognostic (2.63e-2)" "prognostic favorable (5.08e-4)" "unprognostic (2.52e-1)" "unprognostic (3.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" 8.4 8.9 8.9 9.9 10.5 23.3 13.4 8.9 10.0 10.0 1.5 10.6 11.6 10.1 29.6 15.3 10.9 8.9 15.0 13.6 13.2 14.4 23.8 10.0 11.6 8.0 6.8 16.2 7.3 15.2 7.3 12.1 7.7 12.9 10.6 26.1 11.3 12.1 8.3 10.5 12.1 9.0 4.6 12.4 10.9 14.7 9.9 15.3 12.1 15.9 12.5 10.0 9.9 6.1 13.7 16.9 18.2 10.3 16.2 16.5 18.6 7.8 7.8 5.9 5.5 8.6 15.6 16.3 3.1 14.3 9.7 8.0 22.5 10.7 6.5 38.7 17.9 28.5 8.5 13.8 8.5 5.8 7.2 14.5 11.7 7.9 11.3 9.2 4.0 11.7 9.2 24.0 6.9 13.7 14.5 5.8 9.6 15.7 7.9 14.1 7.6 10.3 9.3 22.5 13.8 10.2 13.4 7.1 11.0 12.7 16.7 10.5 5.3 8.4 10.6 10.8 4.2 31.5 17.3 15.4 8.6 7.6 12.5 3.1 1.6 2.2 2.2 2.3 1.5 1.3 1.3 1.9 1.5 2.1 1.5 1.6 5.7 1.4 5.2 0.6 2.0 1.2 8.9 10.5 8.9 10.0 13.6 13.2 8.0 6.8 7.7 4.6 9.9 6.1 20.9 12.8 25.1 161.6 27.3 16.2 8.6 10.8 17.6 25.8 29.5 17.5 34.1 28.6 25.8 25.8 52.1 22.1 26.9 30.8 11.7 9.3 6.4 23.6 26.4 17.7 25.2 28.8 158.9 12.4 12.5 21.6 21.4 38.0 22.2 23.2 22.1 65.9 17.4 74.0 314.8 17.4 10.2 46.8 17.8 7.6 19.9 28.1 21.4 233.3 23.1 14.3 19.6 249.8 186.0 12.8 14.8 22.2 49.9 15.5 22.7 17.6 19.0 33.4 26.3 22.5 20.2 13.3 16.5 18.8 21.5 31.7 36.6 10.9 17.0 15.8 TRAM1 "TRAM, TRAMP" ENSG00000067167 "Translocation associated membrane protein 1" Q15629 8 70573218-70608416 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Translocation, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 670.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023929 Approved NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 55: Plasma cells - Humoral immune response" "HPA023929: AB_1858239" "unprognostic (3.85e-2)" "prognostic unfavorable (2.06e-4)" "unprognostic (8.34e-3)" "unprognostic (1.31e-1)" "unprognostic (3.52e-2)" "unprognostic (5.93e-2)" "unprognostic (8.94e-2)" "unprognostic (2.21e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (3.39e-3)" "unprognostic (3.61e-2)" "prognostic unfavorable (7.79e-4)" "unprognostic (7.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.31e-1)" "unprognostic (3.85e-2)" 93.2 82.8 26.6 95.9 28.9 102.3 115.8 27.6 42.1 139.2 47.7 85.4 91.7 93.4 148.5 65.2 78.5 117.7 59.8 24.8 31.1 120.7 190.2 146.3 103.5 32.5 27.9 73.4 175.5 117.3 38.8 146.8 32.4 87.2 79.7 33.3 193.9 86.0 26.7 49.2 93.6 96.7 29.1 90.0 94.7 61.0 29.1 98.6 170.7 54.9 114.3 120.2 47.7 34.5 171.1 172.5 73.6 45.2 352.6 367.8 105.2 302.9 301.7 231.7 279.1 109.9 275.8 169.1 58.5 259.6 91.3 219.3 67.6 262.1 221.8 112.2 76.1 118.5 54.6 125.7 515.4 91.3 66.3 441.5 249.6 114.2 410.8 238.5 196.7 85.0 77.8 430.3 288.6 47.2 210.4 65.7 48.3 132.3 81.0 100.9 55.3 113.8 610.5 160.4 53.4 54.2 195.0 389.0 180.5 103.1 144.1 102.0 195.3 141.0 117.5 162.4 102.0 338.7 140.1 85.5 160.3 92.9 105.0 150.1 97.3 64.9 120.8 107.7 153.5 107.9 132.1 137.6 114.3 87.9 119.6 125.2 28.2 130.7 113.7 190.4 146.8 232.7 26.6 28.9 27.6 42.1 24.8 31.1 32.5 27.9 32.4 29.1 29.1 34.5 138.3 275.7 132.0 19.6 166.4 85.5 85.2 214.0 69.4 23.7 114.2 62.4 43.0 131.5 209.3 178.4 14.6 154.3 200.5 69.3 68.4 174.5 142.8 77.9 140.7 134.3 44.2 59.7 27.4 247.7 236.7 177.0 70.8 186.6 72.4 59.0 137.8 202.9 182.7 23.5 26.1 95.5 156.6 134.9 251.0 222.2 127.4 123.7 202.7 29.0 132.1 65.6 128.8 34.2 40.3 290.5 51.0 94.4 670.6 199.6 78.0 147.0 110.2 32.9 124.9 76.4 99.5 134.8 56.8 72.3 88.5 194.3 154.2 78.2 65.5 130.6 LACTB2 CGI-83 ENSG00000147592 "Lactamase beta 2" Q53H82 8 70635318-70669185 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.0" "Cell type enhanced" "Detected in all" "Early spermatids: 286.3;Proximal tubular cells: 325.7;Spermatocytes: 263.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 437.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044391, HPA053040" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 37000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Nucleoplasm, Golgi apparatus" "HPA044391: AB_10965168, HPA053040: AB_2682022" "unprognostic (6.33e-3)" "unprognostic (3.13e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-2)" "unprognostic (1.82e-1)" "unprognostic (4.29e-2)" "unprognostic (1.61e-1)" "unprognostic (2.34e-1)" "unprognostic (8.10e-2)" "unprognostic (3.95e-1)" "unprognostic (7.73e-3)" "unprognostic (1.96e-1)" "prognostic favorable (5.60e-4)" "unprognostic (3.70e-1)" "unprognostic (7.49e-2)" "unprognostic (2.93e-1)" "unprognostic (5.93e-2)" 20.4 39.3 6.4 12.9 8.0 3.2 18.4 8.4 9.0 10.8 8.7 21.9 38.8 9.6 11.5 10.2 9.3 28.7 29.8 5.8 8.3 77.0 96.0 20.1 15.6 8.1 7.9 10.0 14.8 21.0 8.3 10.6 8.9 15.4 21.3 12.7 15.0 9.2 28.2 12.4 33.8 15.7 8.1 11.5 16.0 63.2 7.6 14.5 20.2 32.1 13.5 13.2 7.9 10.6 65.7 66.4 20.8 8.6 35.6 53.7 12.5 36.0 20.7 37.7 28.2 32.3 72.3 0.1 14.4 17.4 75.7 45.9 25.0 38.0 30.2 38.8 26.6 30.5 8.1 18.0 74.0 30.1 25.5 64.6 44.8 18.6 28.2 18.0 10.0 23.2 53.4 60.1 50.6 19.6 17.1 5.5 22.3 88.2 60.3 15.2 12.1 14.0 146.3 33.8 29.6 10.3 79.7 437.8 41.0 27.0 72.7 40.1 16.0 3.0 20.8 67.4 29.4 47.7 38.1 0.2 21.1 50.6 28.7 15.8 13.8 13.0 8.5 16.8 10.6 12.6 8.8 8.4 17.3 11.7 8.3 9.2 5.8 11.0 16.7 11.9 13.4 5.9 6.4 8.0 8.4 9.0 5.8 8.3 8.1 7.9 8.9 8.1 7.6 10.6 15.1 57.7 45.1 3.6 16.0 16.4 22.1 58.9 12.5 15.4 12.1 15.1 38.4 18.6 43.9 18.4 8.4 25.1 12.0 27.2 76.3 51.2 286.3 29.4 11.7 15.3 12.1 19.6 3.9 117.2 15.3 15.1 20.4 31.5 9.5 8.7 19.2 76.1 48.0 8.4 4.6 25.8 34.6 34.5 11.2 40.9 20.5 24.2 16.0 3.7 19.4 35.3 8.2 2.5 10.3 70.2 25.1 15.1 18.3 16.0 59.8 325.7 44.9 14.7 6.6 9.6 14.4 263.1 25.0 12.4 16.8 19.4 13.9 34.2 34.7 11.0 XKR9 ENSG00000221947 "XK related 9" Q5GH70 8 70669339-70790371 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.3;testis: 7.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 42.0;Inhibitory neurons: 17.9;Oligodendrocytes: 23.0;Spermatocytes: 82.3;Spermatogonia: 19.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 3.3;hTCEpi: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA044430 Enhanced Approved Mitochondria NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 45: Intestine - Brush border" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Mitochondria "HPA044430: AB_10961283" "unprognostic (1.79e-2)" "unprognostic (7.31e-2)" "unprognostic (1.42e-1)" "unprognostic (1.40e-3)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (2.23e-2)" "unprognostic (9.33e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "prognostic unfavorable (7.20e-4)" "unprognostic (2.29e-1)" "unprognostic (6.96e-6)" "unprognostic (3.65e-1)" "unprognostic (3.26e-1)" "unprognostic (4.04e-3)" "unprognostic (3.71e-2)" 0.2 1.1 0.5 0.4 0.5 0.5 0.4 0.0 1.6 0.2 0.0 0.9 2.6 0.2 1.3 0.5 0.1 2.2 0.2 0.5 0.3 0.5 3.3 0.6 0.5 0.6 0.2 0.2 0.3 0.1 0.6 0.4 1.1 0.6 0.5 2.4 0.5 0.0 0.2 0.9 5.3 0.3 0.0 0.5 1.8 7.7 0.3 0.5 0.4 0.3 0.5 1.0 0.2 1.5 2.3 0.1 0.5 0.2 0.0 0.5 0.3 0.9 0.4 0.3 0.9 3.3 0.2 0.3 1.5 0.0 1.1 0.1 0.0 0.5 1.1 0.4 0.3 0.2 0.2 0.2 0.0 0.7 1.2 0.6 6.4 0.1 0.0 0.2 0.0 1.6 0.1 2.3 0.1 0.3 0.4 0.3 1.3 0.1 0.4 0.3 0.6 0.1 0.1 1.7 1.4 0.2 0.4 1.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 0.4 0.3 2.0 0.5 1.5 0.1 0.2 0.2 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.4 0.2 0.0 0.2 0.6 0.4 0.1 0.2 0.0 0.0 0.8 0.0 0.5 0.5 0.0 1.6 0.5 0.3 0.6 0.2 1.1 0.0 0.3 1.5 0.1 6.4 2.2 14.4 1.1 2.7 3.5 3.9 4.6 2.2 0.7 1.0 0.4 1.5 3.3 0.0 8.4 1.0 0.3 1.4 0.0 1.6 5.3 0.5 0.3 0.6 0.0 0.0 42.0 4.6 0.6 0.8 6.1 0.6 0.0 0.3 0.0 2.3 0.3 1.7 17.9 3.4 0.0 0.3 0.4 4.9 0.9 0.2 0.0 1.9 0.0 1.5 2.1 1.5 23.0 6.0 1.3 0.4 0.8 1.7 11.7 0.5 3.2 5.3 0.0 0.1 0.2 82.3 19.7 0.5 0.9 1.0 1.0 0.1 0.4 2.3 EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.7;parathyroid gland: 23.7" "Cell type enriched" "Detected in some" 11 "Astrocytes: 214.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 27.6;RH-30: 21.3;RPMI-8226: 9.5;SH-SY5Y: 51.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 20.7" HPA028917 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Nuclear bodies" "HPA028917: AB_2672826" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (1.15e-1)" "unprognostic (1.72e-3)" "unprognostic (5.95e-2)" "unprognostic (9.17e-2)" "unprognostic (2.91e-4)" "unprognostic (1.98e-1)" "unprognostic (1.03e-1)" "unprognostic (1.81e-1)" "unprognostic (9.72e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-12)" "unprognostic (1.06e-2)" "unprognostic (1.84e-1)" "unprognostic (3.81e-4)" "unprognostic (1.25e-2)" 0.6 0.6 2.8 0.1 7.8 0.0 0.2 0.5 2.1 5.1 18.7 0.1 0.1 0.1 0.1 0.4 2.0 0.3 4.5 1.3 2.5 0.1 0.0 0.4 0.0 2.1 4.9 0.2 0.0 23.7 10.8 0.0 2.3 12.0 0.2 0.4 0.8 4.0 2.8 0.0 0.2 0.2 0.0 0.1 0.8 0.8 4.6 11.7 0.6 2.5 0.1 2.6 4.3 0.6 0.2 0.0 6.4 27.6 0.0 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 1.6 0.0 0.0 4.7 0.0 2.2 0.0 0.0 0.5 0.0 6.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.0 1.0 0.0 0.0 0.0 2.0 0.0 1.5 0.0 21.3 9.5 0.0 0.0 2.2 51.4 0.0 0.0 1.6 5.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 6.3 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 7.8 0.5 2.1 1.3 2.5 2.1 4.9 2.3 0.0 4.6 0.6 0.2 0.0 0.0 214.5 0.0 0.1 0.0 6.4 0.6 0.1 0.0 0.1 8.8 0.0 7.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 4.4 3.1 0.1 0.2 0.0 0.0 1.3 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 13.5 0.0 2.0 0.0 0.0 6.4 0.3 0.0 0.0 11.2 0.0 0.1 0.0 18.6 0.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 10.5 0.2 0.0 0.2 0.5 0.8 1.0 1.1 0.1 0.5 0.0 1.4 0.0 0.1 MSC "ABF-1, bHLHa22" ENSG00000178860 Musculin O60682 8 71841560-71844412 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 40.9;Fibroblasts: 31.4;Leydig cells: 42.6;Melanocytes: 26.6;monocytes: 50.7;Pancreatic endocrine cells: 27.5;Peritubular cells: 41.3;Sertoli cells: 26.3;Skeletal myocytes: 70.0;Smooth muscle cells: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 25.8" "Group enriched" "Detected in many" 37 "B-cells: 6.9;dendritic cells: 6.4;T-cells: 25.8" "Cell line enriched" "Detected in many" 15 "HDLM-2: 819.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "cerebral cortex: 16.3;hippocampal formation: 13.2" HPA062878 Supported Nucleoplasm NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "HPA062878: AB_2684891" "unprognostic (2.58e-2)" "unprognostic (1.62e-1)" "unprognostic (1.86e-1)" "unprognostic (1.35e-3)" "prognostic unfavorable (5.21e-4)" "unprognostic (3.70e-2)" "prognostic unfavorable (4.83e-5)" "unprognostic (3.95e-2)" "unprognostic (7.92e-2)" "unprognostic (3.75e-2)" "unprognostic (3.73e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.07e-13)" "unprognostic (1.65e-2)" "unprognostic (1.45e-1)" "unprognostic (7.48e-2)" "unprognostic (1.40e-2)" 13.3 8.9 2.5 11.4 1.2 3.9 7.0 0.4 4.5 6.7 0.9 3.0 2.2 4.8 0.9 3.1 4.2 11.1 19.9 5.9 0.6 6.3 3.6 9.5 12.1 3.1 0.7 5.1 5.2 0.3 3.3 16.3 1.0 5.5 1.1 0.0 4.3 3.1 3.0 3.5 5.3 2.3 0.6 6.4 5.4 3.0 0.7 1.6 4.4 2.4 3.5 20.5 6.5 2.8 0.1 6.2 0.0 0.0 28.1 4.9 0.0 1.2 23.8 0.5 1.3 0.0 0.0 0.0 0.3 4.8 28.5 1.3 0.0 1.5 0.0 819.3 0.3 0.0 0.0 0.0 49.8 0.0 2.8 11.1 0.0 49.2 30.1 11.9 0.0 0.0 0.0 0.0 1.0 0.0 0.0 1.2 6.7 0.0 0.0 0.0 55.3 0.0 0.0 0.0 2.4 0.0 0.1 0.0 44.9 0.5 0.0 5.5 0.0 0.2 0.1 7.8 0.3 5.0 0.2 0.1 20.4 0.1 34.5 0.0 0.1 0.0 5.2 0.1 7.2 6.9 9.2 25.8 0.1 6.2 0.2 8.7 0.2 0.0 0.3 6.4 13.0 3.2 2.5 1.2 0.4 4.5 5.9 0.6 3.1 0.7 1.0 0.6 0.7 2.8 1.2 0.0 0.0 0.0 2.7 5.1 0.2 0.4 0.0 0.0 0.2 0.3 1.9 0.0 0.0 1.8 0.0 0.1 4.3 0.0 0.0 16.1 0.6 0.3 1.0 4.5 0.0 0.0 1.1 40.9 0.1 31.4 1.5 0.1 0.0 0.0 3.9 0.0 1.8 0.0 0.1 0.0 0.0 0.3 8.9 1.5 42.6 5.8 26.6 0.0 50.7 0.0 0.0 0.0 0.2 27.5 0.0 41.3 7.0 0.7 0.0 1.2 0.0 0.0 26.3 70.0 27.8 0.4 0.3 0.3 3.3 0.0 10.0 8.1 0.0 0.3 TRPA1 ANKTM1 ENSG00000104321 "Transient receptor potential cation channel subfamily A member 1" O75762 8 72019917-72075584 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 9.2;stomach 1: 10.3;urinary bladder: 27.7" "Cell type enhanced" "Detected in some" "Early spermatids: 10.9;Excitatory neurons: 5.0;Fibroblasts: 8.1;Intestinal goblet cells: 17.2;Skeletal myocytes: 4.5" "Cancer enhanced" "Detected in many" "breast cancer: 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HHSteC: 25.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 27: Mucus-secreting cells - Mucin production" "unprognostic (2.14e-2)" "unprognostic (2.50e-2)" "prognostic favorable (6.57e-4)" "unprognostic (1.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.95e-1)" "unprognostic (1.37e-2)" "unprognostic (8.11e-3)" "unprognostic (4.22e-2)" "unprognostic (2.47e-1)" "unprognostic (2.78e-3)" "unprognostic (1.49e-1)" "unprognostic (2.16e-4)" "unprognostic (2.37e-1)" "unprognostic (9.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.90e-1)" 0.3 0.4 0.1 3.8 0.0 0.0 0.0 0.0 0.7 0.1 0.0 7.9 6.3 0.3 0.0 1.0 0.2 7.0 0.8 0.8 0.0 0.1 0.0 0.2 0.8 0.3 0.0 0.8 0.1 0.0 0.0 0.7 0.0 0.1 9.2 0.0 0.2 0.0 0.1 0.1 7.4 0.3 0.0 0.5 10.3 0.5 0.0 0.2 0.1 0.0 0.2 27.7 0.3 0.2 0.0 2.8 0.8 0.0 0.0 0.1 0.0 0.3 2.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 2.0 0.4 1.5 0.1 0.0 0.5 0.0 25.9 0.0 0.2 1.7 0.0 1.2 0.2 5.5 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.1 0.5 0.0 2.6 0.2 0.0 0.4 0.0 0.1 4.0 1.2 0.0 0.3 0.3 0.0 1.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.7 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 10.9 0.0 0.1 0.0 0.0 0.0 5.0 0.0 0.0 8.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 17.2 0.0 0.0 0.0 0.8 0.3 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.5 0.8 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.5 0.0 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 264.8;Excitatory neurons: 279.1;Inhibitory neurons: 241.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 1.4;HDLM-2: 1.4;HEK 293: 3.4;SCLC-21H: 2.7" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.1 0.4 1.7 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 2.4 2.2 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.5 0.0 1.1 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.3 0.0 1.3 2.3 0.4 0.3 1.5 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.0 1.4 2.4 2.2 1.0 2.6 0.4 1.3 1.5 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 17.4 0.0 0.0 0.3 0.0 0.0 1.8 264.8 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 17.9 0.0 279.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 241.2 0.6 0.0 0.0 0.0 6.8 1.2 0.0 0.0 3.7 0.0 0.7 0.0 11.6 4.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.4 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 TERF1 "PIN2, TRBF1, TRF, TRF1" ENSG00000147601 "Telomeric repeat binding factor 1" P54274 8 73008856-73048123 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048379 Approved "Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoli fibrillar center" "Nuclear bodies" "HPA048379: AB_2680378" "unprognostic (1.02e-2)" "unprognostic (1.66e-1)" "unprognostic (7.24e-2)" "unprognostic (2.42e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-2)" "unprognostic (1.02e-1)" "unprognostic (6.53e-2)" "unprognostic (9.55e-2)" "unprognostic (1.52e-1)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.68e-4)" "unprognostic (2.34e-3)" "unprognostic (1.04e-1)" "unprognostic (9.39e-2)" "unprognostic (1.74e-1)" 13.8 15.2 6.8 4.7 7.7 8.7 13.1 10.9 8.1 13.9 7.0 13.3 8.5 13.8 6.9 9.3 14.7 7.3 11.9 7.6 7.1 14.2 11.2 9.3 7.6 6.3 6.6 17.7 10.1 12.3 11.5 6.6 6.3 12.7 7.3 9.0 10.3 9.4 11.1 10.0 9.4 8.5 7.9 8.1 14.5 10.4 6.5 7.4 11.7 4.7 4.6 18.2 12.4 8.6 17.1 15.5 14.6 12.8 11.0 7.3 14.5 18.4 7.3 10.2 10.7 10.0 13.3 9.4 27.6 9.9 22.2 13.9 19.9 11.3 10.5 14.8 31.7 13.6 3.8 6.9 9.5 7.7 15.9 11.6 7.4 11.2 18.8 14.7 11.0 23.8 14.8 12.3 9.6 10.4 31.3 8.8 60.7 37.7 14.7 21.7 7.0 9.9 17.0 8.7 11.9 15.2 13.6 49.8 14.4 42.6 19.9 5.6 7.5 7.8 13.5 17.0 15.3 15.9 16.0 18.1 10.9 12.0 16.7 11.9 6.5 10.7 11.3 6.0 10.1 12.0 10.5 11.4 7.5 10.7 12.1 12.7 3.6 9.7 7.8 11.4 11.4 6.7 6.8 7.7 10.9 8.1 7.6 7.1 6.3 6.6 6.3 7.9 6.5 8.6 41.5 28.9 29.1 39.5 47.8 27.9 39.6 45.8 35.3 77.6 22.5 32.5 23.2 21.5 27.3 31.3 85.5 53.6 109.4 27.5 25.4 35.8 16.2 24.0 41.1 38.7 92.1 31.6 52.7 37.8 62.4 52.3 24.5 27.1 36.8 44.5 41.7 31.0 34.2 70.7 58.3 26.4 36.7 25.5 26.6 8.1 74.3 27.7 30.2 22.5 32.3 85.7 72.1 48.7 55.3 25.6 21.5 85.4 34.2 30.2 17.9 65.7 24.8 55.4 59.2 63.3 49.1 117.6 131.7 23.6 24.3 31.9 52.6 62.0 28.2 27.6 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 C8orf89 ENSG00000274443 "Chromosome 8 open reading frame 89" P0DMQ9 8 73241329-73259502 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 7.8" "Cell type enhanced" "Detected in some" "Early spermatids: 31.8;Late spermatids: 6.5;Oligodendrocyte precursor cells: 6.6;Spermatocytes: 13.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "memory B-cell: 2.7;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 6 "B-cells: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "unprognostic (4.52e-3)" "unprognostic (1.64e-1)" "unprognostic (7.11e-2)" "unprognostic (2.38e-1)" "unprognostic (6.34e-2)" "unprognostic (3.92e-1)" "unprognostic (1.98e-1)" "unprognostic (1.20e-1)" "unprognostic (3.19e-1)" "unprognostic (1.17e-1)" "unprognostic (4.01e-2)" "unprognostic (4.62e-4)" "unprognostic (5.50e-2)" "unprognostic (2.16e-1)" "unprognostic (9.26e-2)" "unprognostic (6.32e-2)" 0.4 0.2 0.2 0.1 0.1 0.3 0.4 0.1 0.3 1.0 0.1 0.1 0.1 0.5 0.7 0.2 0.2 0.5 0.1 0.2 0.3 0.2 0.0 0.1 1.1 0.2 0.1 0.6 0.6 0.1 0.2 0.4 0.1 0.3 0.1 0.1 0.1 0.3 0.0 0.6 0.1 0.3 0.2 0.3 0.1 7.8 0.4 0.2 0.2 0.0 0.9 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 0.1 0.0 0.6 4.9 0.2 0.1 0.0 0.7 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.2 0.3 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.0 0.0 2.9 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 31.8 0.1 1.4 0.3 0.0 0.0 2.0 0.2 0.1 0.8 0.0 0.1 1.3 0.4 0.0 0.0 0.3 0.0 3.0 0.0 0.0 0.0 0.0 6.5 1.8 0.2 0.0 3.7 0.0 0.0 1.0 6.6 0.8 0.0 0.1 1.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.1 13.1 0.2 0.0 0.0 0.3 0.0 0.5 0.0 0.3 RPL7 "humL7-1, L7" ENSG00000147604 "Ribosomal protein L7" P18124 8 73290242-73295789 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 17748.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058373 Approved Approved "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 380000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" Nucleoli "HPA058373: AB_2683694" "unprognostic (3.75e-1)" "unprognostic (3.60e-2)" "unprognostic (6.99e-2)" "unprognostic (1.80e-1)" "unprognostic (2.37e-2)" "unprognostic (7.32e-2)" "unprognostic (1.45e-2)" "unprognostic (3.41e-2)" "unprognostic (8.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.76e-1)" "unprognostic (3.09e-1)" "unprognostic (1.63e-2)" "unprognostic (9.89e-2)" "unprognostic (5.52e-2)" "unprognostic (3.14e-1)" "unprognostic (2.31e-1)" 2254.0 1352.4 835.1 1322.3 886.2 3071.3 3298.9 846.6 1224.8 2495.7 843.0 1841.6 1316.8 1844.3 1839.2 2058.4 2057.2 1033.9 1342.4 799.0 860.0 1634.0 1593.8 1327.3 2285.6 859.3 828.4 4528.2 3067.3 1217.6 1195.0 1202.5 870.8 1650.4 1681.7 889.4 1843.5 1261.6 2391.6 2826.4 1420.5 1381.5 914.8 1388.9 1853.0 527.0 848.2 2225.3 1616.5 1832.1 2665.8 1978.5 2103.5 900.4 2902.0 2050.6 2163.3 2615.7 4308.7 5473.7 2120.8 3100.6 2474.6 2069.9 1621.0 2487.3 2940.4 8517.8 2467.6 2517.8 1409.2 2703.0 2888.8 3960.2 3204.7 2313.1 2394.1 4682.9 2687.5 2594.4 2583.2 3343.2 2298.0 5174.5 4574.0 1921.5 5950.9 3797.5 3412.0 2840.5 4261.7 3140.1 2980.2 2448.1 5345.2 5080.8 2528.5 5238.5 2182.9 3552.8 2474.4 3353.9 3241.5 2848.0 2977.1 2160.3 1454.9 17748.7 4599.1 1766.2 4497.4 4312.2 3227.1 1575.4 2407.3 2031.7 2913.1 1799.2 2782.6 5514.9 1649.7 4062.8 2654.8 3331.3 7192.1 1787.5 6932.4 5967.0 12630.9 14333.5 12042.7 9069.1 9565.2 12188.2 17585.4 12433.8 894.5 9240.8 5307.0 7970.3 10207.4 26909.6 835.1 886.2 846.6 1224.8 799.0 860.0 859.3 828.4 870.8 914.8 848.2 900.4 622.3 817.3 1610.8 26.1 2654.7 8054.8 9929.5 10766.1 1684.6 268.0 5251.9 4462.2 623.2 2396.3 3812.0 1311.3 125.1 4882.8 1798.3 926.5 5576.1 2795.4 1720.0 1068.3 2371.5 2338.1 1617.8 1779.1 27.0 5044.8 7032.5 2096.9 721.7 1300.7 1491.1 1110.8 2680.0 1876.1 3252.9 94.2 27.6 3112.1 3057.8 3661.5 5169.4 806.4 4246.4 1893.5 3705.1 25.3 4752.6 1792.8 3105.1 19.6 33.6 3149.3 2514.2 2310.6 952.9 5766.4 2274.7 5797.7 1454.2 380.6 1459.4 4118.3 2651.4 953.5 374.0 2143.1 9487.1 4878.7 2546.9 2145.3 4018.0 7816.6 RDH10 SDR16C4 ENSG00000121039 "Retinol dehydrogenase 10" Q8IZV5 8 73294602-73325281 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Club cells: 131.7;Collecting duct cells: 204.1;Muller glia cells: 342.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "ASC diff: 143.6;BJ: 107.4;CACO-2: 97.0;HDLM-2: 110.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049199 Supported "Lipid droplets" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" "Lipid droplets" "HPA049199: AB_2680673" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.13e-2)" "unprognostic (1.14e-1)" "unprognostic (2.80e-2)" "unprognostic (7.87e-2)" "unprognostic (7.98e-2)" "unprognostic (1.18e-3)" "unprognostic (8.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (1.67e-1)" "unprognostic (2.98e-3)" "unprognostic (6.23e-2)" 43.3 6.2 4.2 23.4 5.3 3.3 10.5 4.1 4.1 18.2 16.0 16.6 32.4 14.1 3.9 19.8 7.8 30.2 11.6 4.9 5.9 43.8 41.0 13.6 11.0 11.5 6.8 5.0 34.5 8.4 26.8 36.3 6.4 21.5 15.2 86.3 39.2 13.1 6.9 8.3 30.7 14.9 5.8 7.2 24.8 16.6 20.4 6.1 6.5 8.2 8.8 69.2 11.3 6.7 13.8 39.2 4.3 17.9 143.6 10.5 39.0 107.4 17.4 4.1 6.8 97.0 38.6 9.6 13.9 60.4 6.3 35.6 19.6 15.5 8.4 110.7 49.0 17.0 37.6 30.1 5.6 8.2 18.0 6.3 19.6 16.5 15.3 18.3 15.6 9.4 20.0 13.7 7.0 6.1 8.5 3.4 5.2 84.0 19.0 7.4 4.4 5.8 28.2 19.4 2.6 3.4 9.1 66.3 5.5 5.4 13.1 4.2 24.0 6.3 10.6 28.9 8.3 8.8 10.0 7.8 5.0 7.3 14.7 1.2 0.1 0.2 0.3 0.1 0.2 0.1 0.3 0.4 0.2 0.0 0.6 0.3 0.1 0.0 0.1 0.0 0.2 0.1 4.2 5.3 4.1 4.1 4.9 5.9 11.5 6.8 6.4 5.8 20.4 6.7 14.5 12.8 29.8 3.6 2.5 13.5 9.7 75.6 16.5 3.2 29.1 25.5 9.1 25.8 131.7 204.1 22.9 19.1 11.2 25.5 3.9 16.3 80.6 38.3 50.0 9.7 4.2 1.3 1.4 17.6 23.8 44.6 49.5 71.5 2.5 1.2 3.3 49.2 20.9 3.3 1.0 16.8 40.7 5.4 7.8 9.9 2.8 10.0 17.8 6.5 1.9 342.1 3.1 4.5 2.0 56.9 31.5 3.8 6.4 41.2 47.7 22.6 44.2 16.2 0.0 11.4 20.5 11.0 8.0 24.7 13.9 42.0 7.1 1.6 24.2 17.7 STAU2 39K2 ENSG00000040341 "Staufen double-stranded RNA binding protein 2" Q9NUL3 8 73420369-73747708 "Predicted intracellular proteins" Transport RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 278.9;Inhibitory neurons: 298.3;Oligodendrocyte precursor cells: 157.8;Oligodendrocytes: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MOLT-4: 152.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019155, CAB020836" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "CAB020836: , HPA019155: AB_1857565" "unprognostic (5.75e-2)" "unprognostic (3.39e-1)" "unprognostic (2.31e-3)" "unprognostic (2.47e-2)" "unprognostic (3.76e-1)" "unprognostic (6.27e-2)" "unprognostic (1.07e-2)" "unprognostic (1.18e-1)" "unprognostic (6.36e-2)" "unprognostic (4.01e-2)" "unprognostic (3.31e-2)" "unprognostic (1.89e-1)" "unprognostic (3.62e-3)" "unprognostic (9.94e-2)" "unprognostic (2.98e-1)" "unprognostic (6.44e-3)" "unprognostic (4.25e-2)" 20.2 22.7 24.8 15.8 30.5 24.6 17.8 35.0 39.6 15.3 5.5 17.6 14.9 18.2 19.0 35.1 16.6 24.2 70.6 34.8 22.8 29.5 25.7 17.3 19.3 25.3 25.6 18.2 16.1 29.6 12.5 17.6 25.0 20.9 18.6 34.6 20.5 20.8 110.6 15.0 20.8 23.4 16.2 16.7 16.3 16.8 20.7 35.0 22.9 110.0 22.0 20.8 14.2 35.3 34.7 40.7 63.5 34.5 35.5 25.2 19.3 30.4 27.5 27.1 35.4 15.6 36.0 55.1 31.5 23.9 24.3 27.2 44.5 29.2 39.1 56.1 21.2 74.7 19.4 25.5 18.6 28.4 25.8 18.1 21.6 23.2 15.1 55.8 54.8 48.2 50.5 24.2 36.8 22.6 152.7 22.5 31.4 57.5 26.8 44.9 29.6 46.3 57.6 38.1 24.0 40.2 16.4 43.1 27.4 46.8 51.2 33.3 43.4 26.3 46.0 26.2 22.7 39.4 41.7 51.8 29.3 42.3 22.1 24.4 18.0 42.8 28.6 17.9 21.5 15.7 19.0 24.3 18.4 17.9 16.6 21.7 30.8 44.4 22.8 25.1 26.0 12.8 24.8 30.5 35.0 39.6 34.8 22.8 25.3 25.6 25.0 16.2 20.7 35.3 20.4 9.6 31.1 120.8 22.5 10.6 15.4 16.7 8.6 29.1 24.6 11.8 75.7 21.5 40.7 20.2 41.7 18.4 27.1 22.5 43.0 22.7 22.0 18.6 11.6 26.2 29.9 14.7 278.9 21.7 10.0 20.2 21.4 25.5 20.3 21.8 38.2 58.0 16.1 28.6 298.3 17.6 18.3 24.1 16.8 32.2 9.0 22.5 16.0 129.3 16.9 26.9 43.3 157.8 149.9 17.6 16.5 9.4 20.2 10.9 102.1 37.6 27.6 22.2 0.0 15.8 21.8 12.5 13.8 22.1 19.2 12.2 21.6 20.5 16.1 18.5 UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 154.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045161, HPA073181" Uncertain Approved Nucleoli NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "HPA045161: AB_10960706, HPA073181: AB_2686578" "unprognostic (5.36e-2)" "unprognostic (1.87e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-3)" "unprognostic (3.17e-1)" "unprognostic (9.74e-2)" "unprognostic (3.09e-2)" "unprognostic (6.93e-3)" "unprognostic (1.83e-1)" "unprognostic (3.47e-1)" "unprognostic (1.33e-1)" "unprognostic (2.34e-1)" "unprognostic (5.01e-2)" "unprognostic (4.38e-2)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" 7.5 6.2 5.3 7.5 5.3 11.4 7.0 6.3 7.2 5.9 1.1 5.2 4.5 5.1 5.5 8.7 4.7 8.1 8.3 6.1 3.0 11.2 12.6 7.3 7.1 2.8 2.1 5.4 6.7 8.6 4.6 7.3 3.4 6.0 5.9 10.4 5.7 5.2 8.5 5.5 4.7 6.3 1.6 6.7 5.5 9.5 3.3 7.0 9.1 10.0 7.1 9.7 6.2 4.2 10.3 7.0 8.2 8.0 13.0 14.4 6.8 10.8 12.6 10.6 10.8 5.9 11.1 4.8 8.6 11.7 15.7 10.0 11.2 11.7 16.7 7.7 7.2 10.3 6.5 9.0 8.9 5.6 12.9 10.6 12.2 12.4 21.9 8.5 13.4 5.6 5.1 9.7 16.1 8.7 11.8 6.4 6.2 14.3 13.0 3.8 7.5 4.1 19.7 11.6 5.6 6.5 8.5 26.4 13.2 8.4 13.4 10.0 11.8 12.2 9.4 9.7 8.2 8.7 9.5 3.6 11.2 8.2 11.2 23.8 13.1 17.4 4.7 12.8 5.8 6.8 4.8 3.6 9.1 6.8 4.3 5.0 33.1 7.0 14.4 11.9 6.1 6.9 5.3 5.3 6.3 7.2 6.1 3.0 2.8 2.1 3.4 1.6 3.3 4.2 28.7 16.0 14.0 40.1 30.3 55.3 26.4 32.1 19.4 35.5 26.7 14.7 24.3 37.1 22.9 53.3 16.7 18.4 35.0 14.2 50.9 23.2 154.5 18.3 21.0 35.3 23.3 26.5 117.0 17.4 20.0 24.9 13.3 26.9 21.0 16.8 26.0 28.7 39.9 42.1 91.8 12.1 22.4 50.3 107.9 56.8 20.5 45.7 42.7 104.9 67.0 28.8 21.6 66.9 67.7 20.9 12.4 18.8 21.3 34.1 14.7 76.1 19.2 32.2 19.7 27.3 39.9 39.4 30.4 20.9 64.5 55.1 31.0 30.6 12.9 40.9 ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972287 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 266.1;Extravillous trophoblasts: 326.2;Hofbauer cells: 313.7;Pancreatic endocrine cells: 317.3;Proximal tubular cells: 341.3;Syncytiotrophoblasts: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cell Junctions" "HPA078113: AB_2686877" "prognostic unfavorable (6.48e-4)" "unprognostic (1.60e-1)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (8.02e-3)" "unprognostic (5.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.77e-1)" "unprognostic (6.99e-3)" "unprognostic (4.02e-3)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" "unprognostic (1.67e-1)" "unprognostic (8.95e-2)" 78.3 83.9 86.5 45.0 89.6 93.1 59.9 88.6 116.1 47.9 79.8 61.3 30.2 48.1 67.0 75.3 46.2 39.3 141.0 92.5 85.3 97.2 76.0 62.0 52.5 83.6 83.9 46.1 41.1 58.5 57.2 56.0 83.9 45.2 44.8 69.4 46.7 43.7 190.3 48.4 40.7 54.8 84.2 48.2 57.3 111.2 85.1 64.4 43.3 125.6 65.7 69.3 52.0 89.5 211.2 169.2 151.1 110.2 113.0 146.7 108.1 203.6 165.3 194.8 199.0 151.1 178.2 106.3 160.7 181.9 263.4 147.2 168.7 203.6 256.8 123.2 141.5 185.7 174.2 243.0 147.3 120.4 133.6 149.4 159.9 177.0 226.8 144.2 184.8 180.2 166.2 137.8 260.2 155.9 311.7 214.9 137.5 341.9 271.8 111.9 95.1 100.8 216.2 181.9 142.1 134.3 85.2 458.9 202.4 155.1 169.2 127.9 142.2 140.1 160.6 156.1 208.1 155.6 204.5 198.9 169.6 130.2 175.0 138.6 66.4 85.6 62.0 78.6 68.3 83.1 74.2 70.8 73.6 73.9 66.5 67.5 79.8 73.4 77.3 118.4 99.1 60.0 86.5 89.6 88.6 116.1 92.5 85.3 83.6 83.9 83.9 84.2 85.1 89.5 236.0 67.3 98.9 0.0 24.8 0.0 0.0 0.0 0.0 0.0 147.6 185.4 0.0 0.0 49.5 119.5 0.0 220.1 74.5 0.0 266.1 216.7 0.0 147.9 98.9 77.1 0.0 0.0 0.0 227.2 326.2 66.0 0.0 168.8 69.4 65.9 0.0 0.0 313.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.9 0.0 0.0 112.7 0.0 0.0 0.0 0.0 317.3 0.0 0.0 12.1 0.0 0.0 341.3 63.4 0.0 0.0 0.0 78.2 0.0 0.0 0.0 0.0 332.5 40.7 98.8 0.0 0.0 TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 100.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 78.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Mitochondria Nucleoplasm "CAB034226: AB_2205189, HPA023187: AB_2671101" "unprognostic (2.26e-3)" "unprognostic (4.87e-1)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (1.51e-3)" "unprognostic (8.22e-3)" "unprognostic (9.17e-2)" "unprognostic (1.01e-1)" "unprognostic (7.37e-2)" "unprognostic (7.04e-2)" "unprognostic (2.88e-2)" "unprognostic (9.14e-2)" "unprognostic (3.65e-3)" "unprognostic (6.86e-2)" "unprognostic (5.08e-2)" "unprognostic (2.13e-1)" "unprognostic (2.70e-2)" 18.1 18.2 9.2 9.8 9.7 10.4 11.3 10.5 12.3 8.0 9.5 12.6 5.8 8.9 10.6 9.3 11.3 8.9 19.3 10.3 10.2 12.0 24.4 9.0 10.1 9.6 9.1 10.5 25.0 8.3 7.6 10.3 10.1 7.4 9.7 6.1 9.9 5.9 100.7 7.7 9.5 9.1 9.5 9.6 17.8 9.8 9.5 11.0 6.0 20.5 10.3 11.3 7.4 10.1 21.2 16.4 13.1 13.8 14.9 12.7 13.6 17.6 15.8 19.4 15.3 15.8 11.9 28.4 15.0 12.0 16.4 19.1 24.9 16.8 21.4 18.9 17.5 28.3 10.0 21.2 14.7 15.5 14.5 11.8 15.3 12.2 6.4 7.3 16.4 14.2 22.0 13.5 20.5 15.9 35.8 29.6 12.3 26.6 20.6 25.4 12.8 24.2 20.5 20.0 29.7 13.1 11.0 78.0 23.3 10.2 16.0 14.1 10.6 11.1 13.7 20.7 16.9 19.9 18.7 28.1 16.4 12.1 12.5 6.3 9.1 6.7 8.0 10.2 9.1 17.7 9.0 9.3 9.6 10.9 10.3 9.6 6.7 5.8 7.9 11.0 7.9 12.0 9.2 9.7 10.5 12.3 10.3 10.2 9.6 9.1 10.1 9.5 9.5 10.1 136.2 16.0 30.1 5.5 37.1 67.3 43.7 54.8 24.5 23.9 26.2 22.2 46.3 14.3 35.7 22.0 8.4 71.2 48.1 69.0 66.5 36.6 20.3 40.8 26.2 96.4 13.8 26.5 12.8 63.5 59.6 50.2 17.3 17.1 39.9 17.0 28.5 50.3 132.4 10.1 11.4 31.7 42.7 70.0 74.5 12.1 29.8 73.2 40.9 5.6 38.9 23.1 22.6 3.5 8.1 43.6 37.9 29.0 68.6 42.1 28.8 75.4 58.7 17.5 39.5 61.9 40.8 70.6 29.5 21.5 59.7 70.3 39.8 52.6 34.1 26.2 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 JPH1 JP-1 ENSG00000104369 "Junctophilin 1" Q9HDC5 8 74234700-74321540 "Human disease related genes, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 237.4;tongue: 106.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Basal prostatic cells: 32.8;Cardiomyocytes: 35.7;Excitatory neurons: 82.2;Inhibitory neurons: 50.3;Prostatic glandular cells: 32.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 15.1;OE19: 17.7;SK-BR-3: 34.4;T-47d: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008996, HPA009413, CAB013461" Enhanced Enhanced Nucleoplasm NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm "CAB013461: , HPA008996: AB_1852023, HPA009413: AB_1079163" "unprognostic (2.91e-3)" "unprognostic (3.01e-1)" "unprognostic (8.85e-2)" "unprognostic (8.73e-6)" "unprognostic (2.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.63e-2)" "prognostic favorable (5.77e-5)" "unprognostic (8.97e-2)" "unprognostic (1.30e-1)" "unprognostic (2.38e-1)" "unprognostic (5.99e-2)" "unprognostic (9.80e-2)" "unprognostic (6.87e-2)" "unprognostic (3.03e-1)" "unprognostic (4.88e-2)" "unprognostic (1.08e-2)" 0.3 0.2 2.9 0.5 7.5 0.0 0.7 7.6 5.3 0.7 13.2 3.3 0.7 3.2 0.8 2.8 0.3 0.3 8.4 5.9 1.5 0.8 0.4 3.7 0.1 3.0 1.5 0.1 6.5 0.8 0.5 1.4 2.4 2.8 5.0 0.4 2.8 0.5 237.4 0.6 1.0 1.9 1.9 0.1 0.9 1.0 1.9 3.2 1.4 106.0 1.1 2.3 1.4 3.6 1.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 1.1 1.1 0.5 0.2 4.4 0.0 1.5 0.0 1.0 6.4 5.6 4.3 1.4 0.0 8.3 0.0 5.2 0.0 0.7 2.9 0.3 0.8 3.7 0.0 4.0 0.0 0.0 10.9 0.8 0.0 0.4 4.1 15.1 0.0 9.7 17.7 2.9 7.6 5.4 0.0 0.2 12.7 7.3 1.0 0.1 34.4 1.8 1.6 24.2 0.2 0.0 1.6 2.3 0.6 1.4 0.0 0.0 0.0 2.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 7.5 7.6 5.3 5.9 1.5 3.0 1.5 2.4 1.9 1.9 3.6 1.1 38.5 12.9 3.9 0.2 2.8 32.8 3.0 6.2 0.4 2.4 1.5 35.7 0.0 10.8 1.8 6.2 0.0 0.1 7.1 0.0 0.3 2.4 2.9 8.9 1.7 12.6 0.0 82.2 1.4 0.0 2.6 7.7 3.7 0.0 0.0 0.0 0.0 0.1 0.0 50.3 9.9 2.0 0.0 0.4 0.5 0.9 0.4 1.8 3.7 0.0 0.4 0.0 14.1 4.6 3.4 6.2 0.0 0.0 32.8 0.0 1.0 6.2 0.1 0.0 25.0 1.4 0.1 4.3 7.4 2.0 0.0 0.2 0.1 6.7 25.6 GDAP1 "CMT2K, CMT4, CMT4A" ENSG00000104381 "Ganglioside induced differentiation associated protein 1" Q8TB36 8 74320613-74518007 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 46.9;Cone photoreceptor cells: 47.9;Excitatory neurons: 75.7;Horizontal cells: 47.1;Inhibitory neurons: 67.3;Oligodendrocyte precursor cells: 67.8;Rod photoreceptor cells: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 38.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014266, HPA024334" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Mitochondria Cytosol "HPA014266: AB_1849581, HPA024334: AB_1849583" "unprognostic (3.19e-2)" "unprognostic (1.52e-3)" "unprognostic (2.72e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (3.31e-1)" "unprognostic (4.36e-2)" "unprognostic (1.72e-2)" "prognostic favorable (2.68e-4)" "unprognostic (3.88e-1)" "unprognostic (4.17e-1)" "unprognostic (9.44e-3)" "unprognostic (2.44e-1)" "unprognostic (5.40e-2)" "unprognostic (3.29e-1)" "unprognostic (6.99e-2)" "prognostic unfavorable (4.54e-4)" "unprognostic (2.73e-1)" 2.7 9.6 19.0 3.3 22.5 1.2 4.0 15.2 26.0 2.9 4.9 2.5 2.4 3.9 1.9 4.0 2.8 2.5 2.1 25.3 19.7 4.2 1.5 2.4 3.3 14.5 17.0 6.0 7.4 12.4 20.6 1.2 18.1 4.1 2.4 19.0 2.4 4.1 2.7 1.7 2.3 2.8 12.2 1.9 2.0 4.7 16.7 4.5 6.6 3.1 2.8 3.9 2.6 20.5 3.5 16.8 17.7 4.8 1.2 1.6 1.5 1.8 8.2 8.3 9.5 7.8 5.0 14.8 2.5 1.2 10.6 6.6 12.4 7.0 16.2 19.7 3.6 7.4 8.9 14.0 0.7 7.6 15.8 4.7 2.3 5.3 8.2 0.9 1.1 7.3 3.4 0.3 4.8 5.7 12.6 0.4 20.1 24.5 17.9 8.7 9.2 3.2 2.9 15.3 18.2 38.9 13.1 3.4 9.7 4.9 14.9 2.6 0.0 11.7 6.2 2.9 5.5 9.3 15.7 6.8 7.3 0.3 13.8 0.5 0.9 1.0 0.8 3.1 1.0 1.4 0.8 1.3 0.8 1.3 0.6 0.6 1.8 0.7 5.5 0.2 4.0 0.8 19.0 22.5 15.2 26.0 25.3 19.7 14.5 17.0 18.1 12.2 16.7 20.5 6.4 6.4 5.1 27.1 5.9 1.8 7.4 4.2 6.2 46.9 6.2 6.1 5.9 5.7 3.6 3.7 47.9 0.4 3.9 2.1 9.8 5.2 5.4 15.4 7.0 6.7 20.4 2.1 75.7 5.8 0.3 4.8 3.1 2.8 17.2 2.1 6.4 1.8 4.7 47.1 67.3 1.7 12.2 6.3 2.5 1.3 4.1 4.6 1.8 15.0 2.9 23.5 4.1 67.8 41.9 3.7 1.4 5.7 2.6 2.6 3.6 6.6 4.9 47.7 0.0 8.0 5.5 14.7 13.1 3.7 1.3 0.0 3.1 6.5 1.7 3.8 PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.4;prostate: 31.0;smooth muscle: 49.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.8;Breast glandular cells: 73.2;Breast myoepithelial cells: 13.6;Prostatic glandular cells: 19.3;Smooth muscle cells: 36.2;Urothelial cells: 15.7" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 23.3;SH-SY5Y: 21.3;SK-MEL-30: 30.0;U-266/70: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 6.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" 5.8 1.1 0.6 54.4 0.8 0.0 22.1 0.1 1.6 11.0 0.0 7.8 0.2 19.8 2.1 2.5 20.9 1.5 1.8 0.9 0.9 0.9 0.2 2.2 0.6 0.7 0.8 6.3 0.3 0.0 0.5 0.3 0.4 31.0 4.6 0.6 2.0 6.8 0.4 0.4 4.6 49.9 1.1 1.3 0.7 0.5 2.4 0.4 0.6 0.2 0.2 8.3 6.5 0.6 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.1 21.3 0.0 0.1 30.0 0.4 0.5 0.5 0.0 0.0 0.5 0.0 0.1 7.9 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.1 1.6 0.9 0.9 0.7 0.8 0.4 1.1 2.4 0.6 0.2 0.0 0.0 2.3 0.1 0.1 36.8 0.0 0.6 0.2 73.2 13.6 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.6 0.2 9.1 2.5 0.0 0.0 4.3 0.0 0.4 3.9 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.6 1.9 0.9 0.2 3.6 1.0 0.0 0.0 0.0 0.5 2.0 0.0 0.0 0.0 0.1 19.3 0.0 0.1 0.0 0.5 0.0 1.7 36.2 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 15.7 CRISPLD1 "Cocoacrisp, DKFZp762F133, LCRISP1" ENSG00000121005 "Cysteine rich secretory protein LCCL domain containing 1" Q9H336 8 74984505-75034558 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 29.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 36.1;Endometrial ciliated cells: 62.2;Oligodendrocyte precursor cells: 81.4" "Cancer enhanced" "Detected in many" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 134.4;SH-SY5Y: 72.0;SuSa: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024725 Uncertain "Secreted - unknown location" NA NA 8200 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "HPA024725: AB_1847238" "unprognostic (2.16e-1)" "unprognostic (5.88e-2)" "unprognostic (4.01e-2)" "unprognostic (3.78e-2)" "unprognostic (3.85e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.58e-2)" "unprognostic (5.96e-2)" "unprognostic (2.35e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (7.39e-3)" "unprognostic (2.38e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" 2.7 1.3 3.9 2.5 4.0 1.5 29.4 3.4 3.1 6.3 3.4 2.7 0.7 8.6 4.9 5.0 7.4 10.0 8.8 4.3 8.0 2.1 2.1 2.3 2.8 5.8 10.4 5.7 2.4 19.3 1.2 7.8 8.3 24.6 1.6 3.1 19.3 2.6 0.5 2.3 1.2 7.0 6.3 2.0 0.9 3.8 4.1 9.4 15.1 1.2 1.1 2.5 1.1 10.7 0.0 1.7 134.4 0.0 0.0 0.0 4.5 0.0 0.0 1.6 1.9 0.8 0.0 0.0 19.0 0.0 2.2 0.1 11.3 0.1 0.0 0.1 5.2 0.2 5.1 0.0 3.0 0.0 1.0 7.2 0.3 0.1 1.0 16.6 0.0 1.0 0.0 0.0 0.0 0.1 0.9 0.2 13.9 0.0 5.0 0.0 18.5 0.2 0.0 0.0 0.8 72.0 0.0 0.1 8.0 27.5 10.4 6.4 0.0 3.8 19.6 0.2 0.5 2.4 0.9 0.0 4.6 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.9 4.0 3.4 3.1 4.3 8.0 5.8 10.4 8.3 6.3 4.1 10.7 1.0 3.2 0.0 12.7 0.0 0.8 6.1 1.4 17.6 1.6 10.3 36.1 0.4 0.0 5.4 1.8 0.0 22.7 0.3 0.0 0.0 0.0 15.3 62.2 4.9 3.2 0.0 3.0 15.7 0.0 3.8 9.2 0.0 22.4 3.8 1.8 23.6 0.1 2.0 0.0 11.1 0.0 0.0 0.9 0.0 1.5 4.1 0.4 7.2 1.9 0.0 8.8 0.0 81.4 0.9 0.0 0.0 1.5 0.0 9.4 0.0 0.2 22.5 0.9 0.0 0.4 1.5 1.3 6.0 2.5 1.0 12.0 0.4 6.3 0.0 2.3 HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 114.6" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Distal enterocytes: 51.0;Intestinal goblet cells: 32.3;Paneth cells: 54.3;Proximal enterocytes: 165.3;Undifferentiated cells: 36.9" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.5;liver cancer: 2.8;pancreatic cancer: 4.0;renal cancer: 4.6;stomach cancer: 10.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;CAPAN-2: 16.1;Karpas-707: 4.5;OE19: 10.0;PC-3: 4.8;THP-1: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: AB_1850822, HPA010610: AB_2668318" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (9.44e-2)" "unprognostic (5.60e-2)" "unprognostic (4.65e-2)" "unprognostic (5.26e-2)" "unprognostic (1.27e-2)" "unprognostic (3.92e-1)" "unprognostic (8.09e-2)" "unprognostic (3.68e-2)" "unprognostic (1.83e-2)" "unprognostic (6.93e-3)" "unprognostic (1.67e-2)" "unprognostic (2.11e-1)" "unprognostic (4.22e-2)" "unprognostic (2.47e-2)" 0.2 0.0 0.2 2.5 0.5 0.0 1.0 0.2 0.3 2.3 0.1 20.6 100.5 0.4 1.2 0.3 1.0 12.1 0.0 0.3 0.3 17.4 12.9 0.2 0.1 0.4 0.5 0.0 5.6 0.0 0.0 0.1 0.3 0.6 19.6 0.0 0.4 0.4 0.0 0.0 114.6 0.9 0.4 0.1 8.1 3.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.3 1.1 4.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.3 16.1 0.0 2.2 0.0 1.8 0.0 2.0 0.0 0.0 0.0 1.8 0.0 0.0 2.9 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.3 0.3 10.0 4.8 0.0 0.0 0.3 2.7 0.1 0.3 1.6 0.3 0.1 0.0 0.2 0.2 5.5 0.0 0.3 0.1 0.1 0.0 1.1 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.2 0.3 0.3 0.3 0.4 0.5 0.3 0.4 0.3 0.3 0.0 0.0 1.1 39.8 0.5 0.0 0.6 0.4 2.2 0.0 1.3 0.5 0.2 17.2 1.5 3.7 0.0 0.0 0.0 51.0 5.9 3.2 3.1 3.6 0.2 0.0 16.3 0.0 0.5 4.3 0.0 0.1 8.2 3.2 0.0 0.0 0.0 10.7 0.0 0.0 0.6 32.3 2.0 0.0 0.0 5.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 26.2 0.6 5.6 54.3 0.0 0.0 1.6 165.3 18.5 8.1 0.0 0.0 0.1 0.4 4.8 0.0 0.4 0.0 0.0 0.2 0.0 36.9 2.9 ZFHX4 "FLJ20980, ZFH4" ENSG00000091656 "Zinc finger homeobox 4" Q86UP3 8 76681239-76867281 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3" "Cell type enhanced" "Detected in many" "Astrocytes: 358.5;Bipolar cells: 87.2;Oligodendrocyte precursor cells: 234.2;Oligodendrocytes: 222.6;Skeletal myocytes: 120.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 16.8;TIME: 33.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023837 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nucleoli fibrillar center" "HPA023837: AB_1859013" "unprognostic (2.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.63e-3)" "unprognostic (6.14e-8)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (7.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.79e-2)" "unprognostic (9.15e-4)" "unprognostic (3.18e-2)" "unprognostic (1.17e-3)" "unprognostic (6.20e-7)" "unprognostic (3.50e-3)" "unprognostic (2.51e-1)" "unprognostic (4.50e-4)" "unprognostic (5.89e-4)" 3.0 3.6 7.5 0.5 12.0 0.0 2.1 0.9 9.3 3.2 0.0 3.2 0.0 0.8 3.2 0.3 0.6 0.9 0.4 6.0 18.9 0.3 2.8 0.1 0.3 11.3 23.3 1.9 0.2 0.2 2.8 0.1 17.7 1.0 0.5 2.2 0.6 5.5 2.8 0.4 0.3 1.1 7.0 0.1 0.8 6.7 15.3 0.6 0.3 3.1 0.0 2.7 2.6 15.0 0.0 2.2 3.8 0.0 7.2 8.7 0.0 3.3 4.6 3.8 3.9 0.0 0.0 0.0 5.8 5.7 1.7 0.4 7.8 1.0 7.6 0.0 10.3 0.1 0.0 0.0 1.9 0.0 0.5 16.8 0.4 9.5 3.0 6.5 0.7 0.0 0.1 0.3 7.0 0.0 0.0 0.0 0.6 0.4 7.1 0.0 6.8 0.0 5.8 0.0 0.0 6.5 0.0 0.8 0.0 0.0 0.9 0.0 33.4 3.7 5.6 10.6 7.4 10.9 1.2 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 12.0 0.9 9.3 6.0 18.9 11.3 23.3 17.7 7.0 15.3 15.0 5.4 0.0 1.5 358.5 0.3 0.5 0.1 1.0 2.2 87.2 2.4 2.2 4.0 42.9 0.3 5.5 2.1 0.1 0.2 0.0 0.0 0.1 70.0 0.0 1.1 2.0 0.0 0.0 13.7 0.0 0.0 37.5 0.0 0.0 0.0 0.1 1.1 30.5 0.4 5.0 12.6 0.2 0.0 0.6 1.8 24.3 13.7 0.7 0.0 29.0 0.0 15.0 0.0 234.2 222.6 0.0 0.0 21.4 0.1 0.3 0.0 0.3 0.3 5.8 0.0 120.6 8.1 12.4 2.3 1.2 1.1 0.0 0.6 10.0 0.0 0.9 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PKIA PRKACN1 ENSG00000171033 "CAMP-dependent protein kinase inhibitor alpha" P61925 8 78516340-78605267 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 1160.4;tongue: 953.8" "Cell type enhanced" "Detected in many" "Astrocytes: 104.8;Cardiomyocytes: 367.0;Excitatory neurons: 103.3;Inhibitory neurons: 78.2;Muller glia cells: 82.8;Oligodendrocyte precursor cells: 82.9" "Cancer enhanced" "Detected in many" "glioma: 15.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 21.4" "Lineage enriched" "Detected in many" 9 "T-cells: 21.4" "Cell line enhanced" "Detected in many" "HDLM-2: 63.9;HUVEC TERT2: 104.0;RT4: 100.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042791 Uncertain NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "HPA042791: AB_10795761" "unprognostic (3.83e-3)" "unprognostic (1.89e-1)" "unprognostic (1.55e-2)" "unprognostic (5.59e-6)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (5.10e-3)" "unprognostic (1.65e-3)" "unprognostic (3.25e-2)" "unprognostic (2.58e-1)" "unprognostic (4.12e-1)" "unprognostic (1.00e-1)" "unprognostic (2.93e-1)" "prognostic unfavorable (5.41e-4)" "unprognostic (3.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.52e-3)" 2.5 9.5 44.4 5.6 49.3 2.7 4.1 41.4 49.2 2.2 11.9 3.5 1.2 3.1 3.0 21.5 5.3 8.2 185.9 49.8 44.0 4.7 0.2 8.6 7.6 25.4 34.3 5.8 1.4 108.1 8.0 1.6 36.0 20.3 2.8 33.7 6.2 5.3 1160.4 9.2 2.5 2.6 35.2 4.1 1.6 1.3 48.1 26.3 34.2 953.8 11.0 9.5 3.6 36.2 0.6 0.3 34.2 0.0 18.5 4.8 0.2 32.1 6.3 3.4 7.2 0.0 5.3 14.8 0.2 4.8 3.3 0.5 11.3 10.3 22.3 63.9 24.6 18.5 3.7 0.2 1.2 0.0 10.3 7.7 1.5 0.0 9.6 45.5 104.0 19.8 0.0 15.8 51.4 5.4 28.3 0.0 8.1 0.0 35.3 0.0 29.3 0.0 18.7 100.2 16.6 32.5 4.1 26.4 0.0 8.9 0.0 0.1 41.2 7.8 6.4 1.8 19.2 6.5 6.9 4.9 36.9 0.1 9.8 0.0 0.0 0.0 0.5 0.1 0.4 2.3 9.1 1.8 0.1 2.2 7.7 4.6 0.4 1.7 0.1 0.2 21.4 2.5 44.4 49.3 41.4 49.2 49.8 44.0 25.4 34.3 36.0 35.2 48.1 36.2 0.6 3.2 2.8 104.8 9.8 5.9 8.8 4.5 19.9 40.2 2.6 6.5 367.0 0.0 2.0 1.8 2.1 3.1 2.7 0.4 1.9 0.0 13.9 0.9 0.2 9.1 10.2 4.2 103.3 0.2 2.8 12.3 0.0 1.3 5.7 18.6 2.5 0.0 0.7 58.9 78.2 0.8 6.1 0.0 1.1 5.9 0.0 3.9 3.6 15.0 0.5 82.8 0.0 82.9 17.9 1.5 0.1 0.4 2.3 6.1 0.0 0.1 1.0 6.9 0.0 22.9 4.8 0.4 0.6 13.9 13.8 3.4 8.0 0.1 0.3 3.6 ZC2HC1A "C8orf70, CGI-62, FAM164A" ENSG00000104427 "Zinc finger C2HC-type containing 1A" Q96GY0 8 78666089-78719765 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 44.6" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 45.1;T-reg: 33.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Karpas-707: 42.1;SK-BR-3: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024726 Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Actin filaments" "HPA024726: AB_1846597" "unprognostic (1.12e-1)" "unprognostic (3.02e-1)" "unprognostic (5.36e-3)" "unprognostic (4.00e-2)" "unprognostic (1.13e-1)" "unprognostic (7.79e-2)" "unprognostic (1.19e-7)" "unprognostic (2.96e-1)" "unprognostic (7.25e-2)" "prognostic unfavorable (9.00e-4)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (5.41e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (2.34e-1)" "unprognostic (5.40e-2)" "unprognostic (4.05e-3)" 6.5 5.5 8.4 5.7 9.5 1.6 13.8 11.0 9.9 10.7 1.7 6.2 2.7 19.5 8.4 11.1 19.0 9.7 8.2 9.4 8.4 7.7 2.3 12.6 5.3 9.3 6.9 22.7 3.7 24.0 8.5 6.6 10.1 12.2 7.3 10.9 7.3 9.9 2.4 44.6 4.2 12.1 6.3 5.8 5.5 8.8 7.6 5.1 19.7 6.3 8.4 9.0 8.8 10.9 5.2 6.3 11.6 9.5 24.1 25.2 5.0 14.1 9.4 6.9 8.8 1.7 9.0 8.6 5.8 14.2 14.5 4.2 7.0 7.8 10.1 28.6 4.5 1.0 5.5 5.2 14.3 1.5 2.8 18.2 13.0 5.6 16.8 21.1 9.6 2.9 1.6 42.1 14.6 5.1 1.7 2.5 2.9 0.4 9.9 0.0 14.8 1.8 10.4 11.0 4.5 18.0 11.0 79.2 15.8 10.7 2.0 0.3 7.9 21.4 8.9 9.9 7.1 10.5 11.4 5.8 10.1 0.1 8.3 45.1 6.7 0.2 0.1 7.5 0.0 8.8 6.7 0.4 6.0 6.3 2.0 0.7 0.3 1.2 15.9 0.5 33.3 2.7 8.4 9.5 11.0 9.9 9.4 8.4 9.3 6.9 10.1 6.3 7.6 10.9 21.7 67.3 23.7 71.8 17.0 29.2 38.7 39.9 52.3 26.3 12.3 47.5 15.9 5.7 27.4 18.4 4.2 29.0 1.0 1.8 27.4 18.1 16.3 55.5 38.0 17.5 9.0 1.7 96.4 8.2 29.9 34.5 13.3 25.8 6.3 18.8 21.8 0.8 15.9 47.1 68.3 4.2 16.2 6.0 11.3 5.9 19.3 11.1 16.0 14.0 18.5 39.2 0.0 65.9 52.4 9.4 2.4 36.9 12.5 13.1 0.1 11.8 105.5 25.5 6.6 32.0 33.9 48.6 32.2 26.0 42.3 17.4 6.5 9.4 4.4 14.6 IL7 IL-7 ENSG00000104432 "Interleukin 7" P13232 8 78675743-78805523 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Early spermatids: 108.8;Late spermatids: 145.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.7;naive B-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;HDLM-2: 15.4;HEL: 18.2;HMC-1: 25.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019590 Approved "Secreted to blood" NA NA 60700 "Cluster 19: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "HPA019590: AB_10794621" "unprognostic (3.19e-3)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (5.45e-2)" "unprognostic (9.37e-3)" "unprognostic (3.36e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.28e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-2)" "unprognostic (2.28e-1)" "prognostic unfavorable (2.69e-4)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (6.55e-2)" "unprognostic (2.11e-4)" 2.3 1.2 0.2 4.1 0.3 2.1 1.5 0.4 0.2 2.3 0.3 5.1 6.7 1.1 0.3 3.5 4.8 3.1 0.6 0.3 0.5 1.4 4.2 3.3 8.7 0.6 0.4 0.9 1.0 0.0 0.5 0.3 0.5 1.8 4.4 0.7 1.1 0.9 0.1 8.8 8.7 1.1 0.4 3.5 3.8 1.7 1.2 0.8 1.3 0.1 4.2 2.8 1.5 0.2 0.3 0.0 0.1 0.0 0.4 0.4 0.0 1.4 1.4 1.3 1.9 0.0 7.6 0.1 0.0 4.4 4.5 4.2 0.1 0.0 0.0 15.4 0.0 18.2 0.6 2.1 0.1 0.1 25.4 1.3 0.0 0.2 0.6 4.9 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.1 0.0 5.4 3.2 0.0 2.4 2.6 0.3 0.2 0.0 0.1 0.0 0.2 0.8 0.9 0.0 2.0 0.3 0.0 0.0 3.4 0.0 1.9 5.2 0.3 0.0 0.4 0.2 0.0 9.7 1.0 1.0 2.2 8.7 0.2 0.3 0.0 0.5 0.8 0.3 7.3 0.6 0.2 0.3 0.4 0.2 0.3 0.5 0.6 0.4 0.5 0.4 1.2 0.2 0.6 0.0 3.6 5.9 12.2 6.0 3.2 1.2 10.8 0.1 1.3 0.9 0.7 5.7 2.4 1.8 0.0 0.0 1.3 7.8 9.8 1.2 108.8 22.9 0.8 4.9 3.0 10.5 16.0 5.1 0.0 2.5 11.2 0.6 0.0 0.1 1.8 2.4 0.9 0.0 11.0 6.2 2.0 1.0 3.3 145.5 0.6 1.9 0.0 1.0 3.4 2.0 0.0 20.1 6.0 2.6 11.5 1.2 1.0 1.2 12.4 9.5 24.2 0.4 0.0 2.2 0.5 2.3 0.9 5.2 6.5 0.0 1.6 0.1 4.6 1.7 STMN2 "SCG10, SCGN10" ENSG00000104435 "Stathmin 2" Q93045 8 79611117-79666158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 524.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 182.2;Horizontal cells: 148.0;Inhibitory neurons: 133.0;Rod photoreceptor cells: 53.4" "Group enriched" "Detected in many" 5 "glioma: 26.1;pancreatic cancer: 10.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 2.2" "Cell line enriched" "Detected in some" 9 "SH-SY5Y: 663.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026922 Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Endoplasmic reticulum" "HPA026922: AB_1857605" "unprognostic (4.41e-1)" "unprognostic (3.35e-2)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (8.20e-2)" "unprognostic (9.48e-2)" "unprognostic (1.82e-1)" "unprognostic (6.08e-2)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-13)" "unprognostic (1.14e-1)" "unprognostic (3.86e-1)" "unprognostic (5.77e-3)" "unprognostic (9.59e-2)" 5.8 68.6 161.3 9.6 148.3 0.1 2.8 162.9 524.1 8.4 0.0 22.0 13.9 1.1 0.0 1.0 0.1 3.5 1.0 135.7 343.1 0.2 0.9 0.3 0.7 213.6 140.1 0.5 4.7 0.0 8.9 0.1 257.5 2.6 28.9 87.0 0.9 1.7 0.3 11.5 18.5 6.3 60.9 4.5 5.4 1.9 148.2 0.3 0.2 0.3 1.4 0.4 5.0 165.0 0.0 0.0 5.6 0.0 0.9 0.2 0.3 72.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 64.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 60.5 663.5 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 161.3 148.3 162.9 524.1 135.7 343.1 213.6 140.1 257.5 60.9 148.2 165.0 0.1 0.0 0.0 26.1 0.0 1.0 0.0 0.0 0.0 27.8 0.0 0.3 0.1 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 18.2 0.0 1.5 1.4 24.9 0.0 182.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 148.0 133.0 0.0 0.0 0.0 2.0 8.2 0.3 0.0 1.8 19.7 0.0 16.3 0.0 19.1 23.5 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 53.4 0.0 0.0 0.6 0.5 0.7 0.0 0.9 0.0 0.1 0.0 0.0 0.5 HEY1 "bHLHb31, CHF-2, CHF2, HERP2, HESR-1, HESR1, HRT-1" ENSG00000164683 "Hes related family bHLH transcription factor with YRPW motif 1" Q9Y5J3 8 79762371-79767857 "Cancer-related genes, Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 105.2;Endothelial cells: 47.6;Extravillous trophoblasts: 112.6;Skeletal myocytes: 74.5" "Cancer enhanced" "Detected in all" "glioma: 43.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 6.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.9" "Cell line enhanced" "Detected in many" "HEK 293: 125.7;PC-3: 28.8;SK-MEL-30: 93.3;WM-115: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055599, HPA063472" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Nuclear membrane, Cytosol" "HPA055599: AB_2682858, HPA063472: AB_2685018" "unprognostic (1.15e-1)" "unprognostic (5.06e-2)" "unprognostic (5.13e-3)" "unprognostic (2.12e-1)" "unprognostic (1.86e-3)" "unprognostic (8.47e-2)" "unprognostic (4.21e-3)" "unprognostic (9.56e-2)" "unprognostic (1.72e-1)" "unprognostic (7.22e-2)" "unprognostic (1.25e-2)" "unprognostic (6.71e-3)" "unprognostic (5.92e-3)" "unprognostic (5.77e-2)" "unprognostic (8.53e-2)" "unprognostic (1.74e-2)" "unprognostic (1.00e-1)" 21.1 2.2 17.4 2.1 23.0 0.6 19.0 19.4 19.1 7.2 9.6 6.7 1.7 3.5 0.9 2.8 3.9 4.2 23.9 18.4 20.3 2.8 2.8 15.2 2.2 18.1 21.0 2.0 3.4 3.3 18.4 17.8 19.3 6.0 2.6 5.3 10.1 1.7 19.5 4.2 5.8 3.2 19.1 2.4 4.8 3.1 22.8 3.4 6.5 16.2 2.5 9.3 5.2 15.4 1.7 0.1 1.1 9.1 0.8 0.7 22.0 2.1 2.1 0.3 0.3 0.1 0.1 3.3 2.3 1.0 1.0 4.6 4.9 0.1 0.2 0.5 125.7 0.0 4.1 2.1 1.4 0.0 0.7 1.3 3.7 0.1 16.2 0.4 3.4 0.0 9.0 3.6 1.3 0.1 0.0 0.5 0.1 0.3 28.8 0.0 4.6 3.3 0.4 3.9 5.2 14.6 0.1 2.4 93.3 19.6 0.1 0.1 2.0 0.7 2.4 0.0 1.8 3.3 0.7 0.2 3.4 0.0 31.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.9 0.0 1.3 0.0 0.0 0.0 17.4 23.0 19.4 19.1 18.4 20.3 18.1 21.0 19.3 19.1 22.8 15.4 105.2 0.0 1.8 15.0 0.8 3.2 3.4 27.6 2.8 6.8 8.6 12.2 4.3 0.0 19.5 0.0 0.0 6.8 1.8 5.3 15.6 2.6 4.6 12.6 4.1 47.6 36.8 0.0 7.7 1.2 112.6 5.3 1.5 33.5 10.8 1.9 41.0 0.9 1.8 21.9 8.0 2.0 26.4 0.6 5.7 3.2 0.0 2.3 33.8 20.6 0.0 10.9 0.0 18.6 1.0 0.7 7.5 0.4 0.8 1.7 0.2 0.4 7.7 12.2 0.0 74.5 12.1 0.6 15.4 3.4 3.0 23.4 1.1 1.5 2.5 2.6 MRPS28 "HSPC007, MRP-S28, MRPS35" ENSG00000147586 "Mitochondrial ribosomal protein S28" Q9Y2Q9 8 79918717-80030289 "Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 359.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027202 Approved Supported Mitochondria NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Mitochondria "HPA027202: AB_1854126" "unprognostic (3.63e-3)" "unprognostic (6.41e-2)" "unprognostic (9.61e-3)" "unprognostic (1.31e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-3)" "unprognostic (2.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (4.55e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "prognostic favorable (1.20e-6)" "unprognostic (4.48e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-1)" "unprognostic (7.18e-2)" 47.5 88.8 65.1 32.9 67.7 29.1 47.5 70.0 85.3 33.3 73.0 52.9 30.9 27.3 38.3 41.0 35.2 28.8 104.0 64.0 70.2 79.2 110.9 30.4 37.7 70.1 69.8 28.6 32.3 69.6 40.4 40.9 70.1 31.3 41.0 51.7 35.4 33.4 160.3 29.0 29.4 32.8 69.7 26.7 35.3 24.3 66.9 44.9 53.7 137.7 37.9 39.0 30.7 75.3 85.2 84.1 73.0 17.3 60.9 77.2 79.8 94.3 85.7 122.1 104.2 74.0 66.4 107.2 105.3 75.6 124.2 68.5 102.1 105.5 99.0 85.3 89.8 128.8 74.8 114.4 67.7 57.6 55.3 66.4 88.9 71.8 97.4 67.1 81.0 85.2 93.4 42.3 123.7 81.3 133.8 93.5 29.8 219.5 139.5 89.9 58.1 62.0 158.0 81.8 34.8 58.6 41.1 359.5 91.1 83.8 86.6 68.1 59.0 45.8 116.4 81.6 82.7 46.5 81.4 97.2 77.4 66.7 36.8 95.4 53.8 29.1 48.2 77.3 52.3 51.2 52.8 59.4 98.8 54.4 64.1 62.1 11.1 71.5 70.1 111.1 73.0 49.8 65.1 67.7 70.0 85.3 64.0 70.2 70.1 69.8 70.1 69.7 66.9 75.3 32.5 22.4 22.2 57.8 20.8 35.2 19.5 124.5 36.5 10.9 23.4 28.1 51.6 42.9 67.0 33.1 4.2 78.7 20.9 18.1 101.8 67.3 15.1 28.5 16.1 26.2 37.3 21.7 39.0 47.4 74.3 21.2 17.9 24.1 50.0 10.5 23.9 65.5 49.5 5.0 42.5 23.5 69.2 25.5 28.5 10.4 17.7 26.9 44.4 70.3 40.0 23.7 26.8 93.5 81.8 36.0 20.6 22.2 19.9 13.4 24.5 126.9 79.7 17.2 32.9 31.1 26.1 18.6 33.4 41.6 37.8 59.4 20.0 23.2 36.4 16.0 TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 187.6" "Cell type enhanced" "Detected in many" "Ionocytes: 476.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 50.5" "Group enriched" "Detected in many" 5 "B-cells: 50.5;NK-cells: 15.1;T-cells: 22.0" "Cell line enhanced" "Detected in many" "Karpas-707: 252.6;SK-BR-3: 572.5" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Cytosol" NA NA 310000 "Cluster 43: B-cells - Humoral immune response" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol "Golgi apparatus" "HPA028427: AB_10610561, HPA062167: AB_2684704" "prognostic unfavorable (1.11e-5)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (3.77e-3)" "unprognostic (8.24e-2)" "unprognostic (3.75e-1)" "unprognostic (7.99e-3)" "unprognostic (6.47e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.77e-6)" "unprognostic (2.06e-1)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "unprognostic (1.70e-2)" 5.4 9.2 34.9 28.4 40.2 8.9 75.9 34.2 69.4 19.6 36.6 117.7 98.9 9.9 56.2 34.9 15.3 31.1 11.7 42.9 35.4 46.5 30.7 19.8 44.0 33.2 37.1 2.4 41.8 27.4 34.3 22.9 36.3 104.8 129.7 187.6 80.7 18.3 8.6 46.9 100.3 10.4 32.8 16.0 84.1 5.2 53.3 15.5 64.5 9.8 56.2 20.9 20.2 48.1 131.8 34.9 1.6 23.0 0.0 0.0 51.7 8.6 12.9 34.7 17.1 18.0 37.4 189.9 45.2 0.8 25.5 52.5 52.7 36.3 24.6 23.8 44.2 26.8 46.9 29.4 0.2 8.6 0.7 0.0 25.2 0.1 12.2 21.6 2.0 128.9 0.4 252.6 0.1 43.6 42.6 39.4 11.7 148.8 86.0 0.3 0.7 122.0 60.7 31.6 64.9 44.1 40.1 572.5 110.7 51.0 55.9 34.2 2.1 0.0 35.2 0.6 30.8 94.1 87.1 155.2 22.5 0.2 2.6 0.6 0.1 5.5 12.7 0.1 22.0 50.5 12.4 11.1 2.5 44.7 8.1 9.3 0.5 15.1 0.1 5.2 9.1 8.3 34.9 40.2 34.2 69.4 42.9 35.4 33.2 37.1 36.3 32.8 53.3 48.1 17.3 44.8 67.8 10.4 133.6 80.7 89.6 83.4 51.2 171.1 105.6 54.2 22.2 82.9 78.1 66.2 118.9 98.9 28.6 230.9 170.2 112.8 20.6 25.2 8.4 26.2 169.9 11.6 85.4 79.6 116.9 6.7 97.3 72.8 1.3 15.3 25.7 40.6 13.1 32.0 53.9 331.9 476.0 14.6 24.2 13.0 1.2 10.8 104.9 37.5 91.2 50.3 60.8 69.9 181.0 79.7 317.5 1.5 270.5 214.4 132.3 135.3 21.4 232.2 0.0 49.6 8.3 1.6 18.2 91.4 124.6 231.2 51.3 0.3 247.1 135.4 ZBTB10 "FLJ12752, RINZF" ENSG00000205189 "Zinc finger and BTB domain containing 10" Q96DT7 8 80485619-80526265 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 142.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 48.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021554, HPA050569" Enhanced Enhanced Nucleoplasm NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA021554: AB_1858937, HPA050569: AB_2681179" "unprognostic (7.97e-2)" "unprognostic (3.53e-1)" "unprognostic (2.26e-1)" "unprognostic (6.67e-2)" "unprognostic (9.28e-2)" "unprognostic (8.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.13e-1)" "unprognostic (4.86e-1)" "unprognostic (3.66e-2)" "unprognostic (2.15e-1)" "prognostic favorable (3.52e-4)" "unprognostic (4.65e-3)" "unprognostic (2.40e-1)" "unprognostic (7.15e-2)" "unprognostic (2.63e-2)" 7.9 7.9 4.1 4.8 5.2 23.7 8.2 12.1 4.4 8.7 3.9 6.9 2.0 11.2 6.1 3.7 11.8 7.4 7.5 3.3 5.1 10.2 18.5 6.2 5.3 4.9 4.4 12.7 14.0 7.1 3.5 17.8 5.0 14.1 7.8 7.3 7.6 6.3 5.4 1.9 2.2 8.9 4.3 7.0 4.6 11.2 4.7 8.6 10.1 8.0 3.4 5.5 3.3 5.7 0.0 4.2 21.1 10.7 9.1 6.9 28.5 3.9 0.0 3.0 3.0 9.2 3.4 12.7 11.0 5.8 9.2 0.9 16.7 5.3 3.5 0.0 26.8 6.5 2.8 7.3 5.3 2.2 2.9 6.5 4.6 3.7 10.6 2.5 7.7 10.5 5.9 24.2 2.5 6.7 12.6 5.5 5.3 1.3 6.6 14.7 11.1 4.5 8.4 12.5 12.6 14.6 5.2 48.5 14.8 23.6 9.4 9.1 9.9 7.3 13.5 0.1 3.6 7.0 3.7 14.0 2.8 0.0 9.1 0.1 0.0 0.0 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.4 0.3 0.3 0.0 0.5 0.2 0.9 0.0 0.0 4.1 5.2 12.1 4.4 3.3 5.1 4.9 4.4 5.0 4.3 4.7 5.7 37.1 25.6 17.0 18.9 55.3 28.4 21.1 8.1 44.3 13.4 48.8 39.8 36.1 25.8 11.8 12.9 16.7 38.3 34.1 38.9 3.9 13.1 83.7 82.4 60.6 34.5 60.4 3.0 12.8 6.9 41.0 29.3 40.8 142.6 9.5 37.0 16.8 31.7 13.3 32.0 11.1 43.0 20.3 21.3 79.6 29.7 19.3 32.0 49.8 13.1 11.2 20.8 8.2 19.6 13.4 8.3 14.8 21.1 24.5 82.1 0.4 14.5 19.4 10.6 26.3 46.6 49.5 14.6 10.6 13.6 12.6 105.2 28.4 19.6 34.7 19.6 ZNF704 "FLJ16218, Gig1" ENSG00000164684 "Zinc finger protein 704" Q6ZNC4 8 80628451-80874781 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 170.8;Oligodendrocyte precursor cells: 299.6;Oligodendrocytes: 342.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 72.8;RH-30: 46.0;SH-SY5Y: 58.4;SK-BR-3: 72.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024285, HPA024302" Uncertain Approved Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA024285: AB_2219847, HPA024302: AB_1859427" "unprognostic (5.23e-2)" "unprognostic (1.39e-1)" "unprognostic (2.27e-1)" "unprognostic (3.39e-3)" "unprognostic (6.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (1.26e-1)" "prognostic favorable (4.02e-4)" "unprognostic (1.68e-2)" "unprognostic (1.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.90e-2)" 9.9 5.3 14.6 1.8 18.3 0.7 8.5 27.5 12.0 18.7 0.0 7.3 2.8 16.9 7.2 3.0 13.3 6.3 12.2 12.0 9.7 9.2 3.7 7.5 1.4 14.4 14.4 19.8 20.0 13.8 2.2 5.1 12.8 10.2 6.1 2.5 14.9 8.3 6.5 5.0 4.7 7.2 10.7 3.2 5.2 4.4 14.3 6.9 6.0 7.9 1.1 6.4 7.6 29.9 0.0 2.6 11.5 0.1 0.0 0.0 15.7 0.1 0.0 0.1 0.0 1.3 1.9 0.1 4.5 0.0 0.9 72.8 1.1 2.0 0.0 0.0 12.1 4.3 5.7 9.8 0.0 0.8 0.3 0.4 0.1 0.0 0.3 0.1 4.7 0.6 0.0 0.4 0.1 7.6 11.2 0.2 1.0 6.3 1.1 7.7 46.0 0.2 0.0 25.4 14.5 58.4 2.3 72.2 21.3 3.8 11.6 1.6 0.2 0.0 11.8 0.2 2.5 0.1 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 14.6 18.3 27.5 12.0 12.0 9.7 14.4 14.4 12.8 10.7 14.3 29.9 31.6 51.3 25.9 63.0 0.4 18.5 25.5 4.8 16.5 21.3 28.6 23.4 35.0 21.5 16.5 25.8 0.0 8.8 1.1 20.7 5.9 21.6 20.0 25.5 52.6 21.9 13.8 3.8 112.8 24.5 6.5 40.1 10.7 35.9 27.8 28.7 30.0 10.6 3.2 20.2 170.8 24.7 8.2 5.7 15.7 46.8 32.9 3.6 32.0 56.2 0.0 17.0 0.0 299.6 342.4 9.4 26.5 25.6 0.2 34.7 17.9 18.1 12.8 3.1 13.1 45.1 29.5 1.8 4.2 5.4 5.1 2.9 3.4 60.3 26.2 36.2 PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 169.6;granulocytes: 124.5;Melanocytes: 140.5;Microglial cells: 166.8;Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 35.4;HMC-1: 45.5;SK-MEL-30: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" 3.9 3.1 3.4 9.0 3.5 12.3 2.0 14.8 4.0 1.8 4.3 9.2 7.6 1.9 2.2 1.6 1.8 7.1 4.7 2.8 3.7 1.7 4.7 14.9 14.5 4.5 4.5 1.2 14.9 0.9 2.0 16.0 4.9 2.6 8.7 5.0 3.7 2.1 1.3 4.3 9.0 3.0 4.9 9.1 4.4 0.7 5.2 10.4 1.8 2.1 14.0 4.8 2.6 5.6 0.1 0.1 4.8 0.2 8.9 8.5 0.1 2.0 15.5 1.0 1.9 0.3 0.1 35.4 0.2 0.5 7.6 1.5 0.1 1.8 0.9 0.9 4.5 20.8 0.3 0.0 9.1 3.4 45.5 4.1 1.2 8.9 8.2 0.9 0.0 6.2 0.2 0.1 14.8 0.3 12.6 0.3 0.4 8.1 1.4 9.5 2.4 0.1 1.6 7.6 1.0 1.7 0.0 0.3 36.1 0.8 1.2 3.5 0.3 1.1 0.6 0.0 1.2 5.7 1.6 12.3 9.7 11.7 8.5 13.1 1.4 2.0 2.5 6.4 6.1 2.0 6.2 4.4 1.9 1.6 4.9 3.8 2.3 1.7 14.6 4.1 7.2 2.7 3.4 3.5 14.8 4.0 2.8 3.7 4.5 4.5 4.9 4.9 5.2 5.6 6.2 0.0 12.4 40.8 37.0 31.5 3.9 5.2 0.6 39.7 2.2 2.2 15.4 10.0 14.0 3.7 0.0 0.8 39.0 169.6 0.0 4.0 3.5 0.6 4.4 10.9 3.6 3.8 57.5 6.5 26.2 24.3 8.2 1.1 124.5 97.0 12.5 10.3 27.1 63.9 60.0 23.2 6.1 73.6 26.2 2.1 2.5 79.1 140.5 166.8 40.8 34.9 19.6 82.4 75.3 2.0 62.1 7.9 38.4 7.7 109.3 0.4 0.8 3.2 124.9 32.3 37.1 0.2 3.0 3.8 22.6 2.3 78.1 11.8 27.4 13.7 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 PMP2 "FABP8, M-FABP, MP2" ENSG00000147588 "Peripheral myelin protein 2" P02689 8 81440326-81447439 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transport "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 50 "brain: 278.7;choroid plexus: 97.2" "Group enriched" "Detected in some" 16 "Astrocytes: 84.9;Muller glia cells: 48.5;Oligodendrocyte precursor cells: 88.4;Oligodendrocytes: 90.3" "Cancer enriched" "Detected in some" 59 "glioma: 239.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "WM-115: 1.4" "Not detected" "Not detected" "Region enriched" "Detected in all" 9 "spinal cord: 1313.6" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "unprognostic (5.87e-2)" "unprognostic (5.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.95e-1)" "unprognostic (8.03e-3)" "unprognostic (1.10e-2)" "unprognostic (8.45e-2)" "unprognostic (4.43e-2)" "unprognostic (7.21e-2)" "unprognostic (4.41e-1)" "unprognostic (3.27e-3)" 1.8 1.4 155.1 1.4 168.0 0.0 0.7 231.4 193.1 1.3 97.2 1.4 0.4 0.1 1.8 0.8 0.3 1.1 2.0 146.1 206.4 0.4 0.2 0.1 0.0 278.7 243.1 0.2 0.4 0.0 0.7 0.0 257.4 1.8 0.7 0.2 1.0 3.7 0.3 0.3 0.6 0.3 247.1 0.0 0.6 0.1 214.0 0.0 0.3 0.8 0.0 0.9 1.1 275.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.1 168.0 231.4 193.1 146.1 206.4 278.7 243.1 257.4 247.1 214.0 275.2 1.4 0.0 0.0 84.9 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.8 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 4.7 0.0 48.5 0.0 88.4 90.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.8 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 FABP9 "PERF, PERF15, T-FABP" ENSG00000205186 "Fatty acid binding protein 9" Q0Z7S8 8 81458253-81461579 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "skin 1: 40.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA073619 Enhanced NA NA "Cluster 61: Skin - Cornification" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA073619: AB_2732229" "unprognostic (2.99e-1)" 1.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.0 40.9 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.2 0.2 0.1 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "adipose tissue: 3787.4;breast: 2195.7" "Cell type enriched" "Detected in many" 17 "Adipocytes: 24359.7" "Group enriched" "Detected in all" 7 "breast cancer: 42.1;cervical cancer: 141.7;head and neck cancer: 133.8;urothelial cancer: 65.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 171 "ASC diff: 4051.5;RT4: 2107.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA002188, CAB024961" Enhanced NA NA 22000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "CAB024961: , HPA002188: AB_1078822" "unprognostic (4.81e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-3)" "unprognostic (2.63e-2)" "unprognostic (2.58e-1)" "unprognostic (8.70e-3)" "unprognostic (1.78e-3)" "unprognostic (1.67e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-1)" "unprognostic (9.32e-2)" "unprognostic (1.56e-1)" "unprognostic (8.76e-2)" "unprognostic (1.13e-3)" "unprognostic (4.48e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-1)" 3787.4 42.2 0.8 46.7 1.1 2.8 2195.7 0.9 1.6 9.9 34.8 52.9 2.8 4.6 0.6 15.1 10.9 68.1 121.8 1.2 0.8 7.0 5.1 113.5 13.6 0.8 0.8 4.2 16.6 59.1 1.4 186.9 0.8 4.3 33.5 2.6 58.8 5.0 66.7 65.2 44.7 14.2 0.7 6.7 26.5 1.1 3.8 29.8 83.0 166.7 2.0 242.7 18.9 0.9 0.0 0.0 0.0 0.0 4051.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 17.9 0.0 0.1 1.3 0.0 0.4 0.0 0.0 2.0 0.7 0.0 0.0 0.0 0.8 1.2 0.1 3.0 0.0 9.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 2107.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.2 5.7 0.0 0.2 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 1.6 1.2 0.8 0.8 0.8 0.8 0.7 3.8 0.9 24359.7 35.3 64.3 0.0 19.4 14.4 1.1 0.9 4.6 0.5 71.7 196.2 42.1 0.0 26.7 0.0 0.0 0.5 73.6 0.0 0.0 0.2 1.6 0.4 8.8 1132.7 0.0 0.0 0.0 5.6 0.7 53.1 1.1 0.2 27.8 0.1 23.2 0.4 114.2 0.0 0.0 0.0 0.0 50.4 15.7 10.9 1.5 192.7 16.0 0.0 0.6 0.9 0.0 0.0 0.0 0.2 2.2 1.2 2.7 0.5 0.0 0.3 21.9 2.4 716.6 62.2 1364.8 0.0 0.1 1.2 13.9 0.7 18.7 2.3 0.0 55.3 FABP12 ENSG00000197416 "Fatty acid binding protein 12" A6NFH5 8 81524981-81531378 "Metabolic proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "retina: 72.0" "Group enriched" "Detected in some" 4 "Early spermatids: 83.1;Late spermatids: 150.3" "Cancer enhanced" "Detected in single" "cervical cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044041 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 34: Spermatids - Unknown function" "HPA044041: AB_10962213" "unprognostic (1.18e-1)" "unprognostic (7.31e-3)" "unprognostic (3.07e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.5 0.0 0.0 3.9 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 72.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.4 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.6 2.3 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 83.1 0.0 0.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 150.3 0.6 0.0 0.0 0.0 0.0 4.1 0.0 2.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.5 0.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 IMPA1 IMPA ENSG00000133731 "Inositol monophosphatase 1" P29218 8 81656914-81686331 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037489 Approved NA No 310000 "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA037489: AB_10671757" "unprognostic (1.78e-1)" "unprognostic (3.59e-2)" "unprognostic (6.95e-3)" "unprognostic (2.15e-3)" "unprognostic (1.31e-1)" "unprognostic (6.27e-2)" "unprognostic (3.80e-1)" "unprognostic (2.46e-2)" "unprognostic (1.06e-1)" "unprognostic (4.68e-2)" "unprognostic (7.78e-2)" "unprognostic (6.26e-2)" "unprognostic (2.52e-2)" "unprognostic (5.87e-2)" "unprognostic (1.84e-1)" "unprognostic (2.42e-1)" "unprognostic (5.41e-3)" 12.8 11.3 12.7 12.7 13.3 27.0 10.2 11.8 15.8 8.9 14.8 26.9 23.5 10.4 11.7 20.7 11.8 11.8 25.8 14.6 12.6 16.4 31.3 10.2 17.6 10.9 13.4 13.5 8.6 15.5 10.1 8.2 13.0 11.0 28.4 18.2 8.3 8.1 14.1 5.1 23.2 18.0 12.4 11.2 14.7 38.2 12.1 19.6 21.8 29.0 16.3 14.0 10.5 15.1 12.5 34.6 23.3 17.2 14.0 21.9 9.8 35.7 26.5 31.3 36.7 16.3 20.1 47.2 27.5 26.2 45.6 9.4 27.1 12.0 41.3 50.7 26.5 35.7 19.2 20.8 23.8 36.7 35.0 20.3 17.6 24.9 48.2 30.2 35.2 35.6 32.8 38.7 30.6 8.7 46.1 18.4 10.1 32.2 37.2 21.2 16.9 19.2 31.7 43.5 9.3 38.7 23.9 6.2 41.3 39.6 20.4 27.4 26.4 24.9 32.8 19.8 44.1 45.2 58.5 67.4 29.4 20.7 35.9 50.5 6.6 29.4 13.6 10.3 16.8 20.3 13.5 14.9 7.5 13.7 14.0 16.8 11.2 20.5 11.8 12.0 19.6 9.5 12.7 13.3 11.8 15.8 14.6 12.6 10.9 13.4 13.0 12.4 12.1 15.1 22.2 16.0 12.7 15.3 25.7 13.8 16.9 16.8 28.5 15.8 8.5 6.9 38.3 21.5 17.3 9.2 14.6 9.7 29.4 54.4 31.3 16.2 4.0 23.2 19.7 16.5 21.5 11.6 19.4 20.3 11.0 16.1 12.2 17.3 33.0 11.5 13.9 32.9 14.3 25.2 12.5 19.8 18.3 16.2 13.1 8.2 15.5 16.4 12.4 12.2 21.9 23.4 13.4 14.1 14.0 19.0 62.3 15.1 18.1 14.4 30.4 30.7 25.1 15.9 13.1 15.5 17.0 78.4 19.2 26.9 8.7 3.0 26.2 18.7 22.3 21.3 SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.9;liver: 11.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.1;Enteroendocrine cells: 3.6;Gastric mucus-secreting cells: 6.1;Hepatocytes: 2.8;Proximal enterocytes: 7.2;Respiratory ciliated cells: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 3.6" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" 0.1 0.2 0.9 0.3 0.9 0.0 0.2 1.8 1.4 0.3 0.0 2.8 3.2 0.3 0.7 0.3 0.3 1.7 0.2 0.8 0.9 1.8 11.3 0.2 0.0 0.6 0.7 0.3 1.0 0.2 1.0 0.0 0.7 0.6 3.7 0.5 0.3 0.2 0.2 0.4 3.9 0.2 0.2 0.3 3.4 0.1 1.0 0.1 0.5 0.3 0.2 0.3 0.2 0.8 0.2 0.2 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.2 0.1 0.2 0.1 0.4 0.5 0.0 0.0 0.2 0.3 0.1 0.2 0.2 0.8 0.6 1.3 0.5 0.1 0.0 0.1 0.1 0.6 0.2 0.8 0.6 0.1 0.2 0.5 0.3 0.3 0.2 0.2 0.4 0.0 3.6 0.2 0.0 0.1 0.2 0.2 1.4 0.5 0.3 0.1 0.2 0.1 0.1 0.5 0.1 0.3 0.3 0.5 0.4 0.5 0.3 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.8 1.4 0.8 0.9 0.6 0.7 0.7 0.2 1.0 0.8 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.3 0.3 0.6 0.0 0.5 0.0 0.0 0.0 0.0 4.1 1.9 0.4 0.0 0.4 0.3 0.2 3.6 0.0 0.9 1.1 0.1 0.1 6.1 0.3 0.0 0.3 0.7 2.8 0.0 0.0 0.8 1.5 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.5 1.9 0.0 0.0 0.4 7.2 1.7 4.1 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 2.4 0.5 ZFAND1 FLJ14007 ENSG00000104231 "Zinc finger AN1-type containing 1" Q8TCF1 8 81701334-81732903 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 239.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023383 Approved Approved Centrosome,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Centrosome, Cytosol" "HPA023383: AB_1859008" "unprognostic (6.45e-2)" "unprognostic (1.48e-2)" "unprognostic (7.74e-2)" "unprognostic (8.90e-2)" "unprognostic (1.23e-1)" "unprognostic (8.04e-3)" "unprognostic (8.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (1.30e-2)" "unprognostic (3.77e-2)" "unprognostic (1.38e-1)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "unprognostic (8.35e-2)" "unprognostic (2.36e-2)" 30.3 26.8 15.2 14.8 15.9 28.6 41.8 19.1 21.4 30.8 11.8 27.6 25.8 35.3 26.9 28.3 32.0 24.2 22.2 15.6 17.4 30.7 35.5 24.5 26.8 15.4 15.7 55.7 53.8 32.3 21.7 18.9 16.7 28.1 29.9 21.0 39.9 26.5 21.6 20.7 23.6 32.5 14.0 25.2 30.0 9.2 16.0 31.8 58.1 27.9 29.6 32.1 23.5 16.4 74.1 23.5 31.3 29.4 40.5 86.0 31.0 42.5 57.8 38.3 48.0 26.4 56.8 72.5 49.1 32.5 41.4 47.2 35.9 61.7 57.4 60.1 36.8 41.1 35.1 29.5 78.7 53.9 26.6 70.8 138.4 26.0 239.0 64.6 46.9 70.6 61.1 96.7 38.6 46.0 65.4 35.6 9.6 147.5 70.1 43.8 26.2 32.5 48.1 67.1 30.8 21.6 30.1 19.3 71.6 35.2 62.6 38.7 29.7 27.2 39.4 38.5 60.5 38.2 26.2 45.3 30.9 4.6 21.9 16.8 29.5 8.4 21.8 21.3 36.7 36.4 35.2 28.8 40.8 27.2 46.6 36.1 2.9 37.0 25.8 24.3 44.1 36.0 15.2 15.9 19.1 21.4 15.6 17.4 15.4 15.7 16.7 14.0 16.0 16.4 44.1 25.6 38.3 14.4 47.9 95.8 73.0 73.0 88.2 27.3 49.7 63.6 18.8 41.5 41.4 25.8 4.2 33.8 32.8 10.0 103.7 27.4 3.4 20.1 25.3 42.8 23.4 31.5 49.2 49.4 45.6 36.3 32.1 21.4 34.9 28.9 41.7 22.5 29.1 23.5 45.3 33.6 36.7 47.7 75.0 3.7 39.7 29.1 49.8 20.6 35.2 15.3 23.7 26.7 29.0 33.6 24.4 29.7 44.4 72.2 28.4 80.1 20.9 15.2 32.9 42.6 48.1 18.5 17.3 53.0 78.4 32.7 42.6 49.1 33.3 61.5 CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 71.6;Pancreatic endocrine cells: 78.7;Proximal enterocytes: 80.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 37.2;CAPAN-2: 41.5;hTCEpi: 51.4;hTERT-HME1: 41.6;OE19: 73.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 48: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: AB_1846670" "unprognostic (3.98e-2)" "unprognostic (6.75e-3)" "unprognostic (1.58e-1)" "unprognostic (5.19e-2)" "unprognostic (3.12e-2)" "unprognostic (2.45e-2)" "unprognostic (5.75e-2)" "prognostic unfavorable (9.33e-5)" "unprognostic (7.54e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.99e-2)" "prognostic favorable (1.96e-6)" "unprognostic (3.29e-3)" "unprognostic (4.95e-1)" "unprognostic (2.67e-1)" "prognostic favorable (6.45e-4)" 1.7 5.8 1.2 2.1 1.3 1.2 16.6 1.6 1.3 7.5 2.8 16.2 41.8 2.3 5.8 22.6 8.7 8.0 3.6 1.1 1.0 13.9 7.7 7.2 0.5 1.5 1.4 0.5 20.1 15.8 10.1 5.8 1.5 10.0 14.8 0.2 28.1 7.6 0.2 29.1 31.7 0.8 1.1 8.5 23.7 1.1 1.4 1.9 17.5 0.5 5.2 9.7 14.2 2.0 37.2 7.6 0.0 0.2 0.0 0.0 16.6 1.9 2.2 0.1 0.0 14.3 41.5 0.1 28.8 0.0 6.4 22.1 0.2 15.7 0.0 0.0 17.9 0.7 9.9 13.6 0.8 0.1 0.1 0.0 51.4 0.0 41.6 15.3 0.0 0.0 10.0 12.4 0.0 18.4 0.1 0.3 0.1 73.1 14.9 0.1 0.0 8.3 36.3 22.0 7.9 0.1 9.9 16.3 0.1 8.5 23.9 0.2 0.0 0.1 8.9 0.1 0.2 6.5 4.3 0.2 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 1.9 0.0 0.1 0.0 0.1 1.2 1.3 1.6 1.3 1.1 1.0 1.5 1.4 1.5 1.1 1.4 2.0 5.3 25.6 21.5 0.0 3.2 4.6 35.4 17.1 18.2 0.0 27.2 29.3 4.1 21.5 22.4 5.5 0.0 40.2 0.6 42.0 25.4 47.4 0.4 18.6 2.9 4.0 9.1 1.7 0.1 71.6 38.9 1.0 25.5 31.0 1.3 6.5 4.2 7.6 4.4 0.0 0.1 36.4 12.2 0.3 0.7 1.3 0.0 0.9 8.8 1.0 0.0 0.0 1.0 0.0 0.1 78.7 52.8 0.0 5.7 28.9 80.4 22.6 19.1 0.0 0.0 0.2 7.0 0.3 0.7 25.0 17.5 44.5 1.3 0.1 34.4 33.6 SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 82.8;Late spermatids: 137.3;Spermatocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA024730: AB_10600220, HPA024731: AB_1857346, HPA024817: AB_10602313" "unprognostic (5.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.40e-1)" "unprognostic (8.41e-3)" "unprognostic (3.21e-3)" "unprognostic (7.54e-3)" "unprognostic (1.24e-3)" "unprognostic (1.33e-1)" "unprognostic (2.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.73e-3)" "unprognostic (7.60e-3)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (3.65e-1)" 10.1 5.2 4.7 6.0 5.7 10.7 8.2 6.6 7.6 8.6 2.5 6.3 6.4 9.7 8.3 17.3 6.2 10.8 8.1 5.3 6.6 6.6 5.5 6.7 5.1 6.1 7.4 9.6 3.1 8.9 3.7 5.5 8.6 7.3 6.6 4.9 5.7 7.7 4.6 11.2 5.7 11.9 5.8 12.0 9.0 14.9 5.7 9.4 8.7 9.4 6.7 7.0 7.7 6.7 13.8 3.8 6.6 6.3 22.9 13.7 7.3 16.6 20.2 14.1 20.6 3.4 11.1 2.2 10.0 11.4 16.5 11.0 5.1 6.8 19.5 19.9 3.1 7.1 5.2 6.2 17.4 2.9 11.5 10.5 10.6 5.4 12.5 15.8 10.0 7.8 4.5 26.0 32.9 7.2 15.6 5.1 2.8 12.6 6.2 6.6 9.5 2.4 12.7 6.7 10.9 8.3 3.1 3.9 8.3 9.8 10.3 5.5 7.7 19.5 15.6 13.5 7.2 15.1 12.5 5.7 8.4 9.1 15.7 9.2 4.5 6.1 2.1 2.8 2.0 1.6 2.5 1.7 4.0 4.4 2.9 2.8 6.2 2.6 2.4 3.0 5.0 1.9 4.7 5.7 6.6 7.6 5.3 6.6 6.1 7.4 8.6 5.8 5.7 6.7 10.6 6.4 9.4 9.8 6.4 25.2 12.1 5.0 9.6 5.5 12.1 7.6 8.8 7.2 9.3 5.5 4.2 2.3 3.7 7.5 5.9 5.9 82.8 9.4 7.8 11.5 3.0 8.2 24.7 6.0 4.0 8.5 10.7 16.2 8.2 5.0 13.9 3.5 5.7 55.5 18.4 6.2 8.2 7.0 10.0 137.3 23.3 7.2 3.6 8.4 2.3 4.3 1.0 23.1 22.2 6.7 5.5 16.1 8.6 12.6 3.7 7.3 10.9 5.2 19.7 12.1 9.3 74.2 26.5 13.0 32.0 9.9 5.4 4.2 4.7 20.7 RALYL HNRPCL3 ENSG00000184672 "RALY RNA binding protein like" Q86SE5 8 84182787-84921844 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 19.8;brain: 68.1;kidney: 19.2" "Cell type enriched" "Detected in some" 5 "Excitatory neurons: 2828.9" "Cancer enhanced" "Detected in single" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "OE19: 31.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055868, HPA059112" Enhanced Enhanced Nucleoplasm NA NA "Cluster 6: Brain - Smell perception" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA055868: AB_2682950, HPA059112: AB_2683908" "unprognostic (1.13e-5)" "unprognostic (1.62e-1)" "unprognostic (7.48e-2)" "unprognostic (1.36e-1)" "unprognostic (5.04e-2)" "unprognostic (1.25e-2)" "unprognostic (1.74e-1)" "unprognostic (4.82e-5)" "unprognostic (2.74e-2)" "unprognostic (2.52e-1)" 0.1 19.8 31.9 0.2 35.2 0.2 0.1 68.1 40.2 0.0 0.0 0.7 0.3 0.1 0.7 0.0 0.6 5.0 2.3 27.0 27.5 19.2 0.3 0.1 0.1 12.3 17.3 0.0 2.3 0.0 6.1 1.2 22.7 0.2 0.4 9.0 0.6 2.0 0.2 0.2 0.6 0.1 7.6 2.4 0.5 0.4 26.5 0.0 0.1 0.3 0.1 0.1 0.1 28.5 0.1 0.0 4.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 31.5 0.2 0.0 0.4 0.0 0.0 0.0 0.7 0.1 0.1 0.2 0.1 0.2 0.1 0.0 0.4 0.2 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 35.2 68.1 40.2 27.0 27.5 12.3 17.3 22.7 7.6 26.5 28.5 0.0 0.0 0.0 50.6 0.0 0.0 0.0 0.0 0.0 38.5 1.0 0.6 5.0 21.5 0.0 7.3 2.1 0.0 0.0 0.0 178.1 1.0 2.2 0.0 0.0 0.9 1.8 0.0 2828.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 33.7 531.4 0.6 0.0 0.0 0.0 1.5 0.3 0.0 0.0 68.4 0.0 32.8 0.0 495.6 36.3 0.1 0.0 0.0 0.0 0.0 11.7 19.4 0.0 5.2 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 4.0 0.1 0.1 LRRCC1 "CLERC, KIAA1764, VFL1" ENSG00000133739 "Leucine rich repeat and coiled-coil centrosomal protein 1" Q9C099 8 85107215-85146080 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 33.5" "Group enriched" "Detected in all" 5 "Early spermatids: 192.2;Late spermatids: 166.0;Spermatocytes: 224.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012893, HPA075880" Uncertain Supported Centrosome NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Centrosome "HPA012893: AB_1852434, HPA075880: " "unprognostic (1.01e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-3)" "unprognostic (2.37e-2)" "unprognostic (7.67e-2)" "unprognostic (7.76e-2)" "unprognostic (1.47e-2)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" "unprognostic (1.31e-1)" "unprognostic (4.45e-2)" "unprognostic (2.94e-1)" "unprognostic (3.35e-2)" "unprognostic (2.43e-2)" "unprognostic (2.67e-2)" "unprognostic (7.37e-2)" "unprognostic (1.52e-1)" 4.9 4.8 5.8 3.8 6.6 7.4 6.4 6.1 9.7 4.9 4.5 9.0 6.7 6.3 3.8 3.8 4.4 4.1 4.1 5.5 6.2 5.4 3.9 5.2 4.9 6.5 6.4 8.1 3.7 3.8 1.8 2.1 6.8 5.0 9.0 3.0 2.6 5.1 0.7 5.9 6.5 4.5 6.3 4.3 6.0 33.5 6.4 6.6 8.7 1.9 3.6 4.3 4.2 7.0 7.3 1.6 13.4 3.1 6.3 5.6 10.4 7.4 4.8 1.6 2.9 3.5 10.2 5.4 1.2 4.6 8.6 9.8 16.0 4.5 2.6 41.9 1.4 21.2 4.0 5.4 1.9 8.1 5.5 3.1 1.2 4.6 1.0 3.0 1.8 13.7 24.1 4.8 8.5 2.6 24.9 6.3 4.6 28.0 3.3 18.2 8.3 3.7 4.5 5.5 1.7 4.5 3.7 7.1 2.8 8.6 15.8 17.5 2.4 6.3 8.5 6.8 10.3 6.4 6.9 10.5 5.1 20.6 12.5 0.0 0.2 0.0 0.4 0.3 0.2 0.4 0.3 0.5 0.8 0.2 0.4 0.7 0.0 0.7 0.3 0.5 1.1 0.1 5.8 6.6 6.1 9.7 5.5 6.2 6.5 6.4 6.8 6.3 6.4 7.0 12.2 32.1 32.8 6.5 5.8 9.3 11.8 7.7 13.1 7.2 11.3 9.8 12.6 11.5 22.1 25.8 12.5 8.0 9.9 9.3 33.2 7.7 192.2 14.1 12.6 12.0 7.8 33.6 5.3 7.6 11.7 13.9 12.8 8.1 15.2 13.1 11.4 6.8 6.9 25.2 8.3 14.4 2.0 4.1 8.7 166.0 10.2 10.1 5.4 5.6 6.3 10.8 12.3 22.1 13.8 2.9 5.9 14.3 9.1 5.6 7.7 7.9 20.7 5.0 19.7 13.3 15.5 224.3 38.3 14.1 6.5 1.1 6.5 9.8 20.6 10.8 E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "B-cells: 23.7;Plasma cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.4;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.4" "Cell line enhanced" "Detected in many" "AF22: 82.6;Daudi: 158.0;U-698: 77.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" 1.8 3.9 4.8 8.0 5.2 1.7 6.7 4.6 6.5 5.2 5.1 6.6 4.9 4.5 8.1 2.2 8.0 4.3 1.9 5.1 5.8 8.1 3.0 4.1 25.9 5.5 5.2 4.9 4.3 13.2 3.7 5.0 5.0 3.6 7.8 0.9 2.3 3.3 0.4 0.8 3.8 4.1 5.1 6.9 5.5 8.5 5.3 10.7 8.7 0.9 29.6 6.9 0.9 5.5 14.2 15.9 82.6 29.7 1.5 2.2 25.0 2.7 6.9 2.4 7.4 9.6 17.4 158.0 10.3 3.5 28.4 2.6 51.0 4.3 3.0 16.0 20.1 16.4 8.3 22.4 13.4 4.8 0.1 3.3 6.9 3.5 12.0 15.7 2.7 16.5 34.7 1.2 4.6 10.0 15.8 10.8 26.1 28.0 12.9 12.9 3.4 17.9 27.5 10.7 9.8 29.8 1.8 5.8 23.8 32.6 33.5 5.2 0.1 3.7 2.5 4.6 10.5 27.6 20.6 77.1 4.3 4.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 13.4 0.0 0.0 0.1 8.9 0.2 0.4 0.0 1.4 0.0 1.5 0.6 0.6 4.8 5.2 4.6 6.5 5.1 5.8 5.5 5.2 5.0 5.1 5.3 5.5 1.1 0.0 6.5 3.6 23.7 2.3 3.3 1.3 1.2 0.9 5.6 6.0 1.0 5.7 2.9 5.5 10.4 4.1 5.1 3.3 0.0 3.3 7.6 7.3 5.2 1.5 7.8 1.3 7.7 2.6 1.1 3.0 4.1 7.5 1.3 5.5 0.4 2.4 0.5 0.0 4.6 2.7 2.0 0.8 1.0 3.8 1.5 1.9 3.6 4.7 0.3 5.2 4.1 11.6 4.2 3.0 1.7 1.9 29.6 6.9 0.8 5.8 8.6 1.6 0.0 5.0 4.5 8.1 4.6 2.3 2.8 1.1 2.5 4.6 3.7 2.1 RBIS C8orf59 ENSG00000176731 "Ribosomal biogenesis factor" Q8N0T1 8 85214048-85220421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 56.0;Cytotrophoblasts: 105.8;dendritic cells: 39.1;Extravillous trophoblasts: 123.8;Hofbauer cells: 102.1;Syncytiotrophoblasts: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044805, HPA071903" Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 50: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Nucleoli" Cytosol "HPA044805: AB_2679095, HPA071903: AB_2686469" "unprognostic (1.61e-2)" "unprognostic (2.98e-1)" "unprognostic (4.51e-1)" "unprognostic (1.63e-3)" "unprognostic (2.19e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-2)" "unprognostic (1.47e-1)" "unprognostic (1.22e-3)" "unprognostic (1.63e-1)" "unprognostic (1.69e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.03e-2)" "unprognostic (3.16e-2)" "unprognostic (2.29e-1)" "unprognostic (3.84e-3)" 74.4 69.3 55.7 51.0 56.1 83.2 95.2 57.4 72.4 85.3 57.0 81.0 60.6 67.0 91.1 90.2 72.2 42.8 101.1 54.6 58.2 88.5 86.2 52.3 70.8 56.9 55.6 82.7 103.1 60.6 68.9 45.6 57.5 71.6 56.8 45.8 75.2 41.4 78.0 63.9 66.3 48.8 58.5 75.4 99.0 41.5 56.1 75.1 61.3 68.6 71.3 73.9 73.5 59.8 166.6 83.1 122.6 79.4 73.4 140.2 94.8 107.6 102.7 123.1 120.5 97.2 140.0 42.1 86.8 71.8 116.2 112.9 84.8 118.2 138.1 116.6 92.5 242.1 74.2 145.8 87.0 92.5 105.7 120.0 137.0 79.4 99.7 133.3 106.4 145.3 111.9 97.8 103.7 131.0 205.8 173.1 36.1 372.8 143.3 86.9 100.6 188.2 121.2 104.7 40.7 87.1 81.7 132.8 161.0 145.5 154.4 135.9 81.8 78.1 164.9 87.5 104.2 114.1 144.8 197.4 155.8 116.8 88.9 76.6 55.2 39.2 63.5 71.7 76.7 89.3 83.7 78.9 96.9 77.7 95.8 95.0 14.1 104.7 64.4 118.7 90.8 71.0 55.7 56.1 57.4 72.4 54.6 58.2 56.9 55.6 57.5 58.5 56.1 59.8 56.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 0.0 0.0 0.0 0.0 105.8 39.1 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 123.8 27.8 0.0 0.0 0.0 0.0 0.0 0.0 102.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 76.9 7.6 0.0 0.0 0.0 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Proximal enterocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 15.6;OE19: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 1.8 2.1 1.2 1.2 1.2 0.3 2.3 1.4 1.3 2.1 0.7 2.5 12.0 0.9 0.6 5.0 1.1 5.4 3.6 1.0 1.7 5.7 3.7 2.4 0.6 0.9 1.5 1.1 1.1 9.0 2.9 0.3 0.8 1.2 3.0 2.3 4.8 0.7 0.4 5.6 14.6 0.8 0.6 0.7 5.9 0.7 1.1 0.7 5.0 0.3 2.9 2.1 2.5 1.3 0.2 0.4 0.8 0.1 0.5 0.6 0.4 1.0 1.1 0.1 2.9 7.2 5.4 0.4 0.5 1.2 6.0 2.3 2.2 2.9 0.2 1.6 0.9 15.6 2.0 6.7 1.4 0.2 0.6 2.2 0.5 0.2 1.2 1.8 1.6 0.6 4.0 2.9 2.6 0.0 0.3 0.2 0.4 30.6 0.4 0.2 2.2 0.1 8.1 0.3 0.2 0.0 0.5 0.0 1.6 1.0 0.5 0.8 1.5 2.8 3.9 0.1 1.6 1.1 0.6 1.9 5.7 2.2 2.6 0.7 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.2 1.2 1.2 1.4 1.3 1.0 1.7 0.9 1.5 0.8 0.6 1.1 1.3 1.7 3.2 12.4 7.2 2.9 1.8 2.7 2.7 3.4 1.8 7.0 4.7 6.4 4.3 10.5 12.9 33.3 0.3 2.1 12.3 9.8 4.0 11.3 4.7 2.5 2.7 4.8 3.2 12.2 1.6 0.3 2.9 9.7 7.7 0.0 0.3 8.6 5.8 1.1 0.0 13.7 4.3 2.0 2.5 3.3 13.1 0.0 3.0 5.4 1.9 1.0 1.9 8.2 16.1 4.4 4.4 4.3 0.0 6.9 1.9 52.6 21.0 9.5 5.1 0.0 8.1 1.9 1.3 2.1 9.1 3.1 0.3 2.2 1.0 5.4 2.4 CA1 Car1 ENSG00000133742 "Carbonic anhydrase 1" P00915 8 85327608-85379014 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 55 "bone marrow: 1798.9;intestine: 2109.9" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 11487.3" "Group enriched" "Detected in some" 10 "colorectal cancer: 3.4;stomach cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 987 "HEL: 1022.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006558, CAB025790" Enhanced NA NA 4600000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "CAB025790: , HPA006558: AB_1845989" "unprognostic (1.44e-1)" "unprognostic (7.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.57e-3)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (2.84e-2)" "unprognostic (2.03e-2)" "unprognostic (1.73e-2)" "unprognostic (6.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.04e-1)" "unprognostic (5.61e-2)" "unprognostic (3.01e-2)" "unprognostic (2.38e-1)" "unprognostic (3.95e-2)" 2.0 0.4 0.4 0.5 0.3 1798.9 2.1 1.0 1.5 0.3 0.0 1023.3 0.2 1.6 0.1 0.7 2.2 0.3 1.6 0.2 0.2 2.0 6.7 5.9 0.2 0.3 0.3 0.4 0.3 0.1 1.9 20.7 0.3 0.4 2109.9 0.4 1.1 1.8 1.0 1.4 1.8 30.7 0.1 35.4 2.3 0.2 0.5 0.5 0.9 3.4 0.1 0.4 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1022.7 0.0 0.5 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 2.8 0.4 0.3 1.0 1.5 0.2 0.2 0.3 0.3 0.3 0.1 0.5 0.6 0.0 0.0 0.0 4.2 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 2565.3 0.0 0.0 0.5 0.1 0.0 0.5 45.8 11487.3 11.8 0.0 0.0 0.1 0.0 0.1 22.3 0.0 4.2 4.4 0.0 0.0 12.1 159.4 0.0 11.4 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 13.0 2.2 0.0 754.9 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.4 0.1 298.4 0.0 CA3 "CAIII, Car3" ENSG00000164879 "Carbonic anhydrase 3" P07451 8 85373436-85449040 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 5273.7" "Group enriched" "Detected in many" 8 "Erythroid cells: 221.3;Skeletal myocytes: 304.0" "Group enriched" "Detected in many" 7 "glioma: 23.1;prostate cancer: 9.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "HEL: 47.3;RH-30: 78.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004967, HPA021775, HPA026700" Enhanced NA NA 53000000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "CAB004967: AB_437014, HPA021775: AB_1845990, HPA026700: AB_1845991" "prognostic favorable (4.24e-6)" "unprognostic (1.40e-1)" "unprognostic (1.50e-2)" "unprognostic (2.22e-3)" "unprognostic (4.71e-2)" "unprognostic (8.43e-3)" "unprognostic (3.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (3.68e-1)" "unprognostic (4.71e-2)" "unprognostic (3.54e-1)" "unprognostic (3.19e-2)" "unprognostic (1.18e-1)" "unprognostic (9.96e-2)" "unprognostic (1.39e-1)" "unprognostic (2.19e-1)" 43.4 3.8 2.4 0.3 2.3 9.9 6.4 2.7 3.7 5.1 1.4 1.7 1.8 8.3 2.1 64.8 9.8 2.2 19.5 2.3 2.8 3.7 2.4 24.6 0.4 2.9 2.3 1.4 1.3 1.0 3.8 0.3 2.0 89.5 1.1 5.5 15.4 2.7 5273.7 5.2 4.4 19.1 2.5 0.8 4.1 2.9 2.5 1.4 3.0 1018.8 0.6 1.5 5.5 2.8 2.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 1.1 0.0 0.1 0.0 0.1 0.2 0.3 0.3 0.0 0.5 0.2 47.3 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 78.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 2.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.4 2.3 2.7 3.7 2.3 2.8 2.9 2.3 2.0 2.5 2.5 2.8 0.3 3.2 4.2 2.3 0.1 0.5 1.7 0.6 1.2 0.0 14.5 0.6 1.0 5.7 0.6 0.0 6.2 1.1 0.4 0.4 0.0 0.6 24.1 0.4 0.2 2.2 0.0 221.3 2.2 0.2 0.2 9.1 0.0 0.7 0.0 0.2 2.5 0.3 0.4 0.0 2.5 0.4 0.0 0.3 0.4 7.0 0.3 2.5 0.0 0.0 0.0 29.6 0.0 1.5 0.7 0.2 1.7 0.0 0.0 0.5 8.5 0.6 1.0 1.6 0.0 304.0 5.1 0.6 1.3 0.2 1.0 1.6 1.4 0.3 0.9 0.3 CA2 "CA-II, CAII, Car2" ENSG00000104267 "Carbonic anhydrase 2" P00918 8 85463968-85481493 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Disease variant, FDA approved drug targets, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 687.4;stomach 1: 1108.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1773.2;Erythroid cells: 2448.1;Gastric mucus-secreting cells: 1380.7;Muller glia cells: 1536.4;Paneth cells: 781.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 263.8;HEK 293: 1097.8;THP-1: 461.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001550, CAB010102" Enhanced NA Yes 570000000 "Cluster 38: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "CAB010102: AB_626796, HPA001550: AB_1078393" "unprognostic (6.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.05e-2)" "unprognostic (1.63e-1)" "unprognostic (2.59e-1)" "unprognostic (9.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-1)" "unprognostic (5.23e-2)" "unprognostic (1.57e-1)" "unprognostic (9.89e-2)" "prognostic favorable (5.57e-6)" "unprognostic (2.45e-1)" "unprognostic (2.03e-1)" "unprognostic (1.32e-1)" "unprognostic (6.49e-3)" 7.4 10.1 95.9 36.8 127.5 246.8 37.9 122.1 143.8 5.0 444.0 687.4 285.2 2.9 10.6 19.8 2.7 112.7 15.9 105.2 107.8 331.2 273.5 43.1 6.6 115.5 112.0 0.4 55.1 10.1 6.1 19.6 114.2 1.9 643.6 390.4 74.7 68.4 42.7 81.0 31.3 32.3 98.2 8.4 1108.7 21.2 115.6 5.1 15.9 62.8 4.3 2.9 5.2 145.5 3.7 2.8 12.2 0.0 0.1 0.0 31.2 0.0 0.0 0.0 0.0 15.1 0.9 0.0 9.5 0.0 0.1 263.8 37.4 13.2 0.0 0.0 1097.8 35.8 17.0 0.5 0.0 23.7 5.1 0.0 63.9 0.0 3.7 0.0 0.0 0.0 0.3 0.2 0.0 0.4 0.4 41.4 3.7 86.5 0.0 21.2 1.3 0.5 3.7 8.8 0.2 0.3 5.0 0.0 0.1 9.6 0.0 461.5 0.0 0.0 6.6 0.0 0.4 0.4 1.0 0.1 1.8 0.1 0.0 51.2 5.3 8.6 0.2 15.0 7.4 1.3 0.1 0.8 15.4 3.0 0.0 0.0 12.6 0.1 13.4 1.4 0.0 33.3 95.9 127.5 122.1 143.8 105.2 107.8 115.5 112.0 114.2 98.2 115.6 145.5 19.4 16.0 79.9 34.0 19.6 90.6 1.3 152.5 17.6 23.1 56.9 18.4 19.8 430.4 22.4 161.8 64.6 15.2 2.4 1773.2 348.3 60.1 65.9 3.3 1.3 26.7 30.5 2448.1 1.4 11.3 403.1 6.4 1380.7 8.3 15.9 0.4 4.2 135.6 35.4 13.5 22.3 116.0 10.2 11.0 216.5 232.1 3.4 51.8 74.7 6.5 6.6 1536.4 1.0 3.0 226.4 16.1 781.9 2.2 10.3 3.5 0.3 468.2 3.9 66.1 0.0 12.1 8.2 3.1 2.8 31.2 111.7 17.1 11.7 0.7 390.8 0.5 ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154225 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 60.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 209.4" "Cancer enriched" "Detected in many" 9 "renal cancer: 36.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.3;SuSa: 5.8;U-87 MG: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA055327: AB_2682784, HPA058496: " "unprognostic (3.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (8.43e-3)" "unprognostic (5.36e-5)" "unprognostic (4.02e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (8.58e-2)" "unprognostic (1.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" 0.3 0.0 0.6 0.7 1.4 1.9 0.8 0.4 0.7 0.4 0.4 3.1 1.6 0.3 1.4 0.7 0.0 0.5 0.4 0.5 0.7 60.5 0.4 2.6 1.3 0.6 1.1 0.0 0.4 1.3 0.0 0.8 0.6 1.4 3.5 14.0 1.1 2.5 0.0 1.7 1.3 0.4 0.3 1.1 0.3 0.2 1.0 0.5 1.0 0.0 1.1 0.5 0.0 1.4 0.4 0.6 0.3 0.4 0.0 0.3 1.3 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.1 0.0 1.4 1.2 0.4 0.9 0.2 0.2 0.0 0.5 0.7 0.1 0.0 0.4 0.6 0.3 0.0 0.2 0.4 1.1 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.6 2.0 0.1 0.0 0.4 3.3 5.8 0.9 0.0 0.2 0.3 0.4 0.2 0.3 0.2 0.1 0.3 5.1 0.3 0.4 0.7 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.0 0.5 0.2 0.4 0.2 0.1 0.6 1.4 0.4 0.7 0.5 0.7 0.6 1.1 0.6 0.3 1.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.4 0.1 0.0 0.4 0.0 0.1 7.3 31.3 0.0 0.0 0.0 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 30.5 0.0 1.1 0.0 0.0 6.9 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.0 11.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86047109-86088621 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "retina: 2.4" "Cell type enhanced" "Detected in single" "Rod photoreceptor cells: 2.1" "Cancer enriched" "Detected in single" 5 "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 12 "HEL: 9.4" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: AB_1855815, HPA056839: " "unprognostic (1.77e-2)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 SLC7A13 "AGT-1, XAT2" ENSG00000164893 "Solute carrier family 7 member 13" Q8TCU3 8 86214063-86321146 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 234 "kidney: 42.0" "Cell type enriched" "Detected in some" 6 "Proximal tubular cells: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (3.34e-1)" "unprognostic (2.62e-1)" "unprognostic (1.12e-1)" "unprognostic (2.96e-5)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 33.6 22.1 16.3 25.8 21.5 18.2 40.6 19.6 16.3 23.6 24.3 26.9 26.3 23.0 24.6 33.1 18.5 45.3 50.8 14.3 20.7 40.9 111.7 27.2 39.0 18.3 19.0 24.7 28.0 116.3 9.8 36.9 19.7 33.4 33.1 43.2 25.9 25.6 171.4 40.8 28.1 24.6 18.1 45.7 34.3 29.5 19.5 22.7 32.6 122.2 30.6 33.7 15.8 23.1 59.8 27.1 18.3 13.1 23.0 22.4 16.3 21.0 22.5 16.5 19.5 18.9 35.3 24.9 14.0 36.5 22.9 49.3 26.4 34.1 28.5 31.6 21.0 28.7 24.4 44.7 16.8 11.7 14.0 20.5 42.5 18.2 33.3 25.3 74.1 29.0 14.3 28.7 28.4 29.6 27.7 8.1 11.2 82.6 30.0 18.0 21.4 22.5 37.3 44.5 5.5 12.9 21.2 104.7 23.0 39.8 31.3 10.8 84.4 23.9 28.7 26.3 10.7 33.9 22.0 25.7 29.9 1.6 19.0 6.2 2.1 3.9 5.2 1.9 4.6 2.7 6.4 5.3 1.5 2.4 7.5 4.7 1.3 2.4 2.2 1.9 6.5 2.0 16.3 21.5 19.6 16.3 14.3 20.7 18.3 19.0 19.7 18.1 19.5 23.1 51.2 25.6 22.6 29.0 13.0 35.8 26.9 15.4 26.7 28.8 41.7 23.5 82.7 44.3 19.2 29.5 58.4 28.3 19.5 23.7 43.0 20.5 42.1 22.6 20.1 32.3 23.6 3.0 55.3 37.6 3.3 27.6 35.2 35.5 3.8 18.0 62.4 88.8 55.9 40.4 134.6 25.3 14.2 95.2 28.1 12.7 32.3 43.0 30.2 61.8 18.6 23.3 18.6 60.3 103.8 45.1 16.0 36.5 18.5 45.1 15.8 45.7 17.2 52.6 6.6 18.8 16.6 12.4 21.2 28.8 39.5 23.0 32.0 25.1 19.7 38.3 RMDN1 "CGI-90, FAM82B, FLJ20665, RMD1" ENSG00000176623 "Regulator of microtubule dynamics 1" Q96DB5 8 86468257-86514357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026495 Approved Supported "Actin filaments,Centrosome" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Centrosome "Actin filaments" "HPA026495: AB_1848414" "unprognostic (1.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (3.13e-3)" "unprognostic (1.76e-1)" "unprognostic (1.50e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-1)" "prognostic favorable (8.51e-4)" "unprognostic (2.08e-1)" "unprognostic (7.15e-2)" "unprognostic (4.71e-3)" "unprognostic (3.47e-1)" 35.6 26.1 25.8 20.9 30.1 24.7 24.3 30.4 27.8 15.5 25.3 26.7 28.7 17.6 19.8 29.4 21.1 22.5 63.0 23.0 29.5 51.7 56.8 23.4 30.3 29.8 29.7 17.0 17.5 26.3 12.9 18.9 30.0 21.2 29.0 30.9 16.4 20.7 71.7 32.8 29.2 20.2 28.3 25.2 30.6 26.4 29.6 23.0 50.4 70.5 31.5 20.1 16.3 30.5 64.0 27.1 31.3 17.8 60.3 97.8 38.5 45.9 41.1 35.8 34.6 32.2 39.9 76.2 38.1 38.2 33.2 61.0 39.8 46.0 42.1 64.6 31.9 40.2 32.8 82.1 32.1 18.4 1.0 53.3 42.6 47.6 72.9 63.9 81.6 44.3 42.4 40.7 57.5 57.3 65.1 8.6 15.9 111.3 67.5 36.6 43.6 78.9 42.5 39.3 14.8 32.8 38.2 149.2 67.6 32.5 83.9 33.6 44.6 39.5 64.0 50.8 28.2 52.4 46.5 59.7 51.2 28.7 54.4 16.4 38.5 94.2 26.6 50.7 31.1 42.2 27.1 31.3 45.2 30.8 22.3 29.0 15.5 39.0 70.3 51.3 43.2 30.7 25.8 30.1 30.4 27.8 23.0 29.5 29.8 29.7 30.0 28.3 29.6 30.5 24.0 41.7 39.0 38.8 23.8 13.5 13.2 40.1 22.2 14.5 16.8 15.0 117.3 20.0 42.4 20.2 16.7 42.5 29.9 22.2 49.0 42.9 97.8 28.3 26.6 24.3 10.2 27.3 22.5 53.0 57.1 24.0 32.1 24.8 1.3 18.9 21.8 57.7 53.7 20.2 29.9 20.6 18.3 40.1 14.8 77.1 13.1 28.3 16.0 33.7 48.5 27.4 21.6 42.3 51.9 45.8 17.2 9.1 21.8 9.2 45.7 73.0 34.4 21.5 0.0 19.9 32.9 65.7 33.5 31.0 15.5 28.5 21.6 53.1 26.9 15.2 CPNE3 ENSG00000085719 "Copine 3" O75131 8 86514435-86561498 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 249.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029552 Uncertain Supported Nucleoplasm,Cytosol NA NA 71000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA029552: AB_10600703" "unprognostic (5.63e-3)" "unprognostic (1.47e-1)" "unprognostic (2.95e-2)" "unprognostic (4.22e-3)" "unprognostic (9.92e-2)" "unprognostic (6.58e-2)" "unprognostic (8.40e-2)" "unprognostic (4.76e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-1)" "unprognostic (8.64e-3)" "unprognostic (2.77e-1)" "prognostic favorable (5.07e-4)" "unprognostic (1.15e-1)" "unprognostic (4.33e-1)" "unprognostic (1.65e-3)" "unprognostic (1.13e-2)" 35.4 29.3 14.6 22.4 17.4 76.6 42.3 23.0 15.0 40.7 24.3 35.0 32.1 33.2 21.4 73.6 32.0 30.1 52.4 15.5 19.2 51.5 46.2 33.8 39.5 15.3 17.6 39.2 29.7 52.1 11.8 25.5 17.3 41.2 34.2 18.2 37.1 29.9 17.5 36.3 30.8 31.7 16.4 28.4 30.1 8.3 16.2 38.5 60.9 26.4 46.5 34.9 25.5 21.8 135.1 46.8 30.9 40.9 116.9 92.1 24.6 63.3 93.3 51.9 58.2 30.4 44.5 36.7 40.6 77.6 31.6 101.2 68.7 67.5 92.5 39.5 52.1 6.0 27.2 34.7 41.0 2.3 1.5 63.0 71.2 57.6 76.0 83.1 64.6 17.6 33.2 68.4 65.0 51.6 65.9 1.8 10.5 110.6 64.4 30.7 28.9 174.4 67.4 92.2 66.2 51.5 55.4 249.3 39.6 35.7 95.0 10.3 69.3 44.5 44.1 61.3 49.4 47.0 63.3 9.9 66.0 12.6 42.9 28.6 32.6 54.3 33.2 38.1 26.2 26.4 27.5 23.8 63.1 26.9 23.8 26.1 46.5 27.6 52.5 62.2 20.9 32.0 14.6 17.4 23.0 15.0 15.5 19.2 15.3 17.6 17.3 16.4 16.2 21.8 84.1 137.8 103.9 23.2 52.0 81.8 110.6 111.8 96.2 16.2 80.2 73.9 120.2 75.8 89.3 69.9 14.6 73.0 85.4 49.4 99.7 77.9 1.6 66.9 73.5 66.3 50.2 28.4 37.0 83.7 55.1 92.6 48.9 83.5 8.2 44.7 66.4 103.9 50.4 45.4 39.9 55.3 81.4 71.0 93.8 4.5 85.7 64.0 53.4 13.1 75.0 75.6 36.0 58.3 24.5 59.3 51.7 87.6 49.4 112.5 53.3 126.1 78.8 17.4 59.2 102.1 77.4 3.2 8.8 183.2 91.1 78.0 55.2 71.4 75.1 91.8 CNGB3 "ACHM1, ACHM3, RMCH" ENSG00000170289 "Cyclic nucleotide gated channel subunit beta 3" Q9NQW8 8 86553977-86743675 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Stargardt disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.1;retina: 13.1" "Cell type enriched" "Detected in some" 13 "Cone photoreceptor cells: 158.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "SCLC-21H: 18.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA057244 Enhanced NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA057244: AB_2683380" "unprognostic (5.35e-1)" "unprognostic (1.68e-3)" "unprognostic (1.22e-1)" "unprognostic (2.42e-1)" "unprognostic (3.62e-2)" "unprognostic (2.58e-1)" "unprognostic (6.25e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (2.17e-1)" "unprognostic (3.82e-1)" "unprognostic (9.28e-2)" "unprognostic (2.77e-4)" "unprognostic (1.40e-4)" "unprognostic (1.66e-2)" "unprognostic (8.76e-2)" "unprognostic (1.84e-1)" 0.0 0.0 0.2 0.3 0.3 4.1 0.0 1.2 0.5 0.2 1.7 0.1 0.5 0.2 0.1 0.0 0.9 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.2 0.1 0.4 0.4 0.6 0.0 0.0 0.1 0.2 0.1 0.0 13.1 0.3 0.0 0.1 1.2 0.1 0.0 0.1 0.1 0.3 2.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 1.3 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.3 0.0 1.0 18.9 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 1.2 0.5 0.3 0.2 0.1 0.4 0.2 0.1 0.1 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 158.4 0.1 1.3 0.0 0.0 0.0 5.6 0.1 0.6 0.2 0.0 0.0 2.4 0.0 0.0 1.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 11.4 0.0 0.1 0.0 1.0 0.2 1.5 0.0 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 0.1 1.6 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 CNBD1 FLJ35802 ENSG00000176571 "Cyclic nucleotide binding domain containing 1" Q8NA66 8 86866415-87615219 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 6.6" "Group enriched" "Detected in some" 33 "Early spermatids: 155.4;Late spermatids: 92.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "Karpas-707: 4.4;U-266/70: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025037, HPA027469, HPA027786" Uncertain "Secreted in male reproductive system" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025037: AB_10794318, HPA027469: AB_10599492, HPA027786: AB_10600231" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 155.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 92.3 1.2 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCAF4L2 WDR21C ENSG00000176566 "DDB1 and CUL4 associated factor 4 like 2" Q8NA75 8 87870747-87874015 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 214 "testis: 21.3" "Group enriched" "Detected in some" 4 "Spermatocytes: 68.6;Spermatogonia: 75.3" "Cancer enriched" "Detected in some" 6 "testis cancer: 20.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 26 "U-266/84: 7.5" HPA067584 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "HPA067584: AB_2685868" "unprognostic (4.25e-1)" "unprognostic (4.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.37e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.6 0.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.6 75.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757806-89791064 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 156.1;Langerhans cells: 121.3;Macrophages: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" Cytosol "HPA015273: AB_1856299, HPA016499: AB_1856300" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.35e-1)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (6.20e-2)" "unprognostic (1.43e-3)" "prognostic unfavorable (6.33e-5)" "unprognostic (2.06e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.00e-6)" "unprognostic (6.39e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.84e-2)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "prognostic favorable (8.05e-4)" 4.1 1.6 4.0 5.6 4.0 8.9 5.1 4.0 5.5 4.7 3.3 2.9 1.7 5.5 2.4 3.0 2.7 9.4 4.4 4.1 5.5 3.7 5.6 6.0 6.5 4.6 4.0 2.5 4.4 4.2 1.9 4.7 5.1 5.3 2.9 1.5 5.0 2.7 0.6 4.2 2.4 5.7 5.3 4.8 2.9 2.9 3.7 2.8 4.2 1.3 6.7 9.4 2.6 6.0 17.8 6.0 3.2 4.9 7.9 10.8 5.5 19.2 36.1 10.7 13.6 4.6 9.7 14.4 28.0 11.7 7.6 4.2 8.9 6.9 20.2 8.7 8.0 11.9 2.8 5.5 22.2 4.5 5.8 8.8 5.6 15.6 49.8 11.4 11.4 0.0 5.4 4.7 10.2 3.4 0.0 9.6 1.5 8.4 14.4 3.2 4.1 7.5 26.1 8.4 0.4 3.1 4.7 12.6 10.0 4.0 12.0 5.6 10.1 6.5 6.0 11.2 9.1 8.9 4.2 8.8 16.2 0.4 4.3 13.7 6.6 23.2 3.5 12.5 4.1 7.6 5.4 4.6 8.1 4.8 4.9 5.4 5.1 4.4 14.9 2.6 1.3 4.6 4.0 4.0 4.0 5.5 4.1 5.5 4.6 4.0 5.1 5.3 3.7 6.0 19.3 35.3 18.1 25.5 29.8 57.6 33.7 13.3 16.5 2.1 17.2 8.9 5.2 4.3 22.9 3.7 0.0 13.3 32.8 2.8 5.9 80.1 6.6 82.3 23.7 15.0 0.0 9.9 12.9 60.8 45.7 27.3 9.7 156.1 43.1 7.1 6.1 3.2 41.7 3.3 9.1 5.4 24.4 32.4 121.3 2.5 7.8 105.1 19.6 15.0 42.1 12.1 8.2 15.6 12.8 50.0 2.7 6.0 22.0 59.2 2.2 10.4 11.6 0.3 13.1 19.2 19.6 7.9 12.8 14.7 48.3 83.7 30.4 7.5 8.1 49.5 OSGIN2 "C8orf1, hT41" ENSG00000164823 "Oxidative stress induced growth inhibitor family member 2" Q9Y236 8 89901849-89927888 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 246.6;Granulosa cells: 144.4;Late spermatids: 216.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 22.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 22.2" "Cell line enhanced" "Detected in all" "SK-BR-3: 149.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028515, HPA050595" Approved Approved Nucleoli NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Nucleoli "HPA028515: AB_10602014, HPA050595: AB_2681186" "unprognostic (3.29e-2)" "unprognostic (1.15e-1)" "unprognostic (7.09e-2)" "unprognostic (4.32e-3)" "unprognostic (1.42e-3)" "unprognostic (3.26e-2)" "prognostic unfavorable (3.91e-6)" "prognostic unfavorable (2.93e-4)" "unprognostic (2.32e-1)" "unprognostic (2.22e-3)" "unprognostic (4.38e-3)" "unprognostic (1.81e-1)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.66e-1)" "unprognostic (1.09e-1)" "unprognostic (7.25e-2)" 19.2 7.6 9.6 8.6 9.3 51.9 12.1 10.9 12.1 8.6 7.0 10.5 7.9 18.4 5.7 8.3 5.9 16.3 14.8 10.6 17.9 17.1 18.5 16.4 10.8 12.4 11.4 17.8 7.9 33.2 9.8 7.0 12.5 10.0 8.9 12.9 7.4 7.8 15.2 5.2 7.1 21.1 14.9 9.3 6.0 23.1 10.2 8.9 14.1 18.8 10.0 11.0 4.7 18.3 32.1 30.6 7.9 16.2 17.5 14.0 9.9 23.5 49.9 21.7 22.2 14.3 29.6 21.9 45.7 13.0 26.1 11.6 16.0 18.8 34.6 33.3 11.7 34.2 11.7 8.0 31.9 17.0 20.4 16.1 23.2 24.5 22.6 20.9 28.6 28.7 19.7 38.3 16.2 24.8 29.7 11.7 4.4 33.6 16.7 13.1 11.5 18.6 33.2 24.2 7.1 18.1 17.3 149.6 29.5 12.9 30.1 27.9 20.2 23.2 20.2 20.1 22.2 35.0 32.2 24.2 38.6 21.9 17.5 22.2 1.6 7.5 1.9 1.2 2.7 3.5 2.8 1.7 1.8 2.0 2.3 2.6 12.4 2.5 1.5 1.3 3.1 1.6 9.6 9.3 10.9 12.1 10.6 17.9 12.4 11.4 12.5 14.9 10.2 18.3 9.8 64.1 14.8 49.3 10.4 6.0 6.9 9.2 2.8 9.0 13.3 6.7 13.9 17.2 12.5 7.3 2.1 6.8 10.6 4.2 9.8 13.6 246.6 11.6 10.8 7.4 9.6 8.6 14.9 16.0 8.4 13.7 2.0 14.1 17.1 144.4 13.6 17.6 16.5 3.3 14.9 3.8 20.3 19.1 9.4 216.8 12.5 15.7 7.2 9.4 13.3 25.3 5.2 7.5 7.8 14.0 3.4 12.4 6.1 7.2 3.0 14.8 15.2 6.0 13.1 18.9 9.0 28.9 8.8 4.5 4.3 1.6 8.3 3.0 5.1 7.6 NBN "AT-V1, AT-V2, ATV, NBS, NBS1" ENSG00000104320 Nibrin O60934 8 89933331-90003228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 265.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001429, CAB003836" Supported Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Nucleoplasm "CAB003836: AB_562172, HPA001429: AB_1854460" "unprognostic (1.52e-1)" "unprognostic (1.72e-1)" "unprognostic (2.32e-3)" "unprognostic (7.46e-2)" "unprognostic (2.49e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "prognostic unfavorable (5.46e-5)" "unprognostic (5.05e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.15e-1)" "unprognostic (6.68e-2)" "unprognostic (3.14e-2)" "unprognostic (3.28e-1)" "unprognostic (2.84e-2)" "unprognostic (1.03e-1)" 22.5 12.4 9.2 27.8 12.8 54.0 25.4 9.3 10.0 16.9 7.4 18.3 15.1 22.3 11.4 20.0 14.5 22.5 12.1 10.2 12.5 20.7 22.3 18.1 24.3 10.7 8.6 16.9 15.5 15.4 9.0 14.1 9.9 17.5 22.5 9.8 16.6 14.9 10.0 10.3 16.0 24.2 11.0 23.4 12.7 16.4 11.0 19.0 22.7 16.2 26.4 21.8 9.6 15.0 54.8 30.1 29.3 15.6 16.5 38.7 18.9 37.9 49.5 46.6 50.8 17.2 41.8 83.8 42.2 35.5 19.1 17.7 35.7 35.7 59.8 38.0 19.7 67.7 16.8 23.6 30.8 40.0 35.2 30.5 18.3 27.2 57.9 22.8 39.5 33.9 50.6 46.6 55.3 46.9 65.6 26.0 8.5 39.5 31.4 42.3 25.3 47.0 62.8 73.8 8.1 26.6 23.5 265.1 23.1 16.3 49.8 31.4 29.2 40.9 28.0 25.5 38.0 21.2 25.0 45.5 41.3 39.4 39.1 32.4 17.7 32.9 11.9 19.7 12.7 15.2 8.5 8.8 18.9 8.9 8.1 9.0 34.4 16.1 31.5 10.4 5.9 13.1 9.2 12.8 9.3 10.0 10.2 12.5 10.7 8.6 9.9 11.0 11.0 15.0 36.9 48.1 14.2 24.5 39.8 11.9 13.5 20.4 23.9 25.4 29.7 22.9 30.3 14.3 33.7 27.6 2.1 23.0 29.3 11.2 43.0 35.1 17.6 45.4 46.9 22.9 12.1 31.7 45.0 32.0 19.7 36.3 19.9 31.2 79.7 38.3 18.9 30.6 25.9 13.5 39.9 16.9 16.2 29.2 27.1 7.2 19.0 51.1 12.4 32.8 54.7 29.4 36.0 40.7 40.3 24.7 9.9 26.4 38.8 11.6 9.9 40.5 36.4 11.2 6.6 50.3 31.7 20.2 46.0 31.5 13.5 10.8 35.3 68.7 19.4 11.0 DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 290.1;liver: 272.3" "Cell type enhanced" "Detected in all" "Distal tubular cells: 399.2;Proximal tubular cells: 485.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 120000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Cytosol "HPA023160: AB_1847585, HPA023162: AB_1847586, HPA023238: AB_1847587" "prognostic unfavorable (1.49e-4)" "unprognostic (5.76e-3)" "unprognostic (8.37e-3)" "unprognostic (6.13e-3)" "unprognostic (2.01e-1)" "unprognostic (4.45e-2)" "unprognostic (1.68e-2)" "unprognostic (8.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-1)" "unprognostic (9.12e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.79e-7)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (1.16e-1)" "prognostic favorable (6.06e-4)" 60.2 136.8 12.4 9.6 14.4 24.9 54.4 12.5 14.4 29.4 22.2 65.0 20.2 28.0 14.9 52.6 26.1 7.4 290.1 12.7 13.2 103.5 272.3 34.2 15.0 12.2 13.1 35.5 44.4 13.2 32.6 5.9 12.1 28.6 18.8 8.0 42.8 6.5 121.8 43.3 61.0 9.1 12.5 47.1 44.5 52.3 15.4 10.2 33.0 34.4 13.9 31.1 35.8 12.8 13.1 7.9 19.6 16.1 8.0 17.3 5.2 13.2 12.9 5.9 8.2 2.8 13.4 7.7 5.3 15.1 4.1 6.8 7.7 11.1 11.0 12.6 1.2 18.4 13.6 14.5 11.6 8.7 4.4 12.0 7.0 7.6 10.7 10.1 17.4 16.5 21.3 15.5 20.7 16.3 12.5 7.6 1.5 9.1 24.9 7.4 5.8 13.4 23.4 43.9 1.3 10.6 13.0 81.1 7.7 1.1 10.7 7.4 20.1 11.4 6.2 12.9 6.0 10.5 7.5 12.8 8.6 12.0 10.8 3.9 9.1 6.2 7.1 10.2 7.9 7.4 6.9 8.6 8.8 4.6 8.1 7.8 15.2 3.9 9.3 3.9 9.6 5.8 12.4 14.4 12.5 14.4 12.7 13.2 12.2 13.1 12.1 12.5 15.4 12.8 66.1 76.9 59.4 72.5 52.9 41.3 70.6 180.2 35.3 11.4 51.1 57.4 268.3 82.9 96.4 71.7 2.1 50.2 57.6 119.0 399.2 137.8 165.3 68.2 65.5 60.0 104.8 77.4 27.2 92.5 49.0 60.2 61.2 40.6 50.0 81.3 47.8 244.8 115.1 32.0 55.9 105.9 116.0 95.2 82.7 52.6 85.4 85.1 85.4 29.0 107.1 52.5 74.2 66.9 35.0 87.5 111.6 51.6 67.8 30.3 250.3 485.2 69.0 7.6 72.3 54.5 61.7 157.5 24.6 68.6 41.1 41.0 64.4 135.1 139.6 86.8 CALB1 CALB ENSG00000104327 "Calbindin 1" P05937 8 90058608-90095475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 320.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 26.1;Collecting duct cells: 27.6;Cone photoreceptor cells: 91.8;Distal tubular cells: 31.3;Horizontal cells: 99.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;monocytes: 1.4" "Cell line enhanced" "Detected in many" "A-431: 134.9;EFO-21: 189.8;HeLa: 65.9" "Region enhanced" "Detected in all" "cerebellum: 430.7" "Group enriched" "Detected in all" 4 "basal ganglia: 49.7;cerebellum: 119.6" "CAB002138, HPA023099, HPA056734" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB002138: AB_563448, HPA023099: AB_1845859, HPA056734: AB_2683220" "unprognostic (2.19e-1)" "unprognostic (2.28e-3)" "unprognostic (2.61e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.82e-1)" "unprognostic (5.39e-2)" "unprognostic (2.05e-1)" "unprognostic (1.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.37e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (7.88e-2)" "unprognostic (2.24e-1)" "unprognostic (1.42e-1)" 2.4 1.6 7.4 2.0 31.3 1.3 1.7 63.0 21.1 5.5 0.0 1.7 3.2 1.2 3.4 8.5 1.9 1.4 0.9 9.2 14.0 320.6 2.6 3.6 0.9 16.8 10.4 1.2 2.5 2.2 8.4 3.9 6.3 0.8 2.5 54.1 1.7 0.5 1.9 3.5 2.7 1.3 15.9 1.3 2.3 3.6 32.1 2.7 2.5 0.3 1.2 0.5 0.1 7.8 134.9 6.1 30.2 1.2 1.1 4.9 4.0 2.0 5.8 0.7 1.1 2.9 15.1 0.5 189.8 0.1 0.8 47.8 46.0 54.6 9.1 0.3 2.5 3.2 65.9 0.7 5.3 0.8 4.4 1.5 17.3 2.5 25.4 7.0 36.1 2.6 9.9 3.4 35.9 0.6 1.9 0.1 45.3 2.9 17.9 1.3 1.2 3.9 12.9 0.7 5.0 2.9 38.2 2.3 0.6 45.8 1.7 1.1 0.1 3.9 28.1 6.6 11.9 3.1 3.9 1.0 0.5 0.9 0.2 1.5 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 1.4 0.3 0.0 0.4 7.4 31.3 63.0 21.1 9.2 14.0 16.8 10.4 6.3 15.9 32.1 7.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 1.5 0.0 0.0 27.6 91.8 0.0 0.0 0.0 31.3 0.0 14.9 0.0 0.1 0.3 3.5 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 99.3 14.7 0.0 0.0 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 15.8 0.0 1.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.8 0.0 0.3 0.4 0.3 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 TMEM64 DKFZp762C1112 ENSG00000180694 "Transmembrane protein 64" Q6YI46 8 90621995-90791632 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 42.5;epididymis: 144.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 62.0;Hepatocytes: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034221 Uncertain NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "CAB034221: AB_1567653" "unprognostic (3.61e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" "unprognostic (1.14e-1)" "unprognostic (2.27e-1)" "unprognostic (2.55e-3)" "unprognostic (4.84e-1)" "unprognostic (2.04e-1)" "unprognostic (1.26e-2)" "unprognostic (3.30e-1)" "unprognostic (2.35e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" 17.1 12.0 5.2 9.3 9.3 3.4 8.4 7.1 7.1 15.4 42.5 10.5 9.6 10.9 144.9 10.5 8.8 10.4 7.2 4.9 6.8 13.6 20.8 9.5 12.9 9.4 7.4 16.3 15.3 6.8 4.7 10.3 7.8 11.4 5.5 1.0 17.8 17.3 8.9 6.4 9.8 16.3 7.5 8.9 7.1 12.2 7.4 5.1 22.9 7.1 12.1 10.6 7.8 14.5 26.5 20.3 10.0 5.4 45.7 33.0 5.5 19.2 18.2 14.8 16.3 5.7 17.8 17.2 7.5 11.8 6.4 9.0 26.9 13.0 19.5 34.8 9.8 32.1 7.3 12.8 16.1 1.9 5.1 43.4 14.0 6.1 13.8 17.1 15.1 4.1 14.8 36.9 25.1 35.3 0.1 4.6 1.5 13.6 10.6 3.8 22.1 8.7 29.2 50.6 7.1 20.0 12.6 10.9 23.5 13.3 10.9 1.5 15.1 14.9 13.1 10.8 15.8 24.3 0.4 18.8 13.4 3.9 20.0 2.7 0.1 0.1 1.5 0.3 1.9 3.1 1.6 1.7 0.3 2.0 0.7 1.1 0.0 3.2 0.4 0.2 0.8 0.9 5.2 9.3 7.1 7.1 4.9 6.8 9.4 7.4 7.8 7.5 7.4 14.5 16.7 9.6 12.5 5.2 15.7 24.1 12.7 5.4 62.0 0.7 7.3 11.4 20.4 7.2 3.7 22.0 0.0 25.3 18.6 2.5 1.9 3.9 3.7 3.3 9.6 9.0 7.8 18.7 9.9 10.2 6.2 18.1 6.1 4.6 14.0 13.5 6.1 51.7 4.0 1.7 14.1 4.5 8.2 9.7 11.6 3.2 46.9 11.1 24.9 9.4 1.9 4.0 4.1 8.0 46.8 8.8 2.4 21.4 12.6 19.7 16.7 30.6 3.7 0.0 0.0 10.5 11.9 3.4 2.2 17.4 23.4 15.7 13.3 23.7 7.2 8.6 NECAB1 EFCBP1 ENSG00000123119 "N-terminal EF-hand calcium binding protein 1" Q8N987 8 90791741-90959393 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 59.4;choroid plexus: 24.3" "Group enriched" "Detected in many" 4 "Excitatory neurons: 374.6;Oligodendrocytes: 307.8" "Cancer enhanced" "Detected in many" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 4.0;MOLT-4: 4.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210" Enhanced Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Cytosol "CAB068208: AB_2665671, CAB068209: AB_2665672, CAB068210: AB_2665673, HPA023252: AB_1848013, HPA023629: AB_1848014, HPA025963: AB_1848015, HPA031262: AB_2673815" "unprognostic (8.09e-3)" "unprognostic (3.78e-1)" "unprognostic (8.17e-3)" "unprognostic (5.96e-5)" "unprognostic (2.51e-1)" "unprognostic (1.30e-1)" "unprognostic (3.83e-3)" "unprognostic (8.38e-2)" "unprognostic (1.78e-3)" "unprognostic (2.60e-1)" "unprognostic (2.25e-2)" "unprognostic (2.57e-2)" "unprognostic (2.19e-3)" "unprognostic (4.45e-3)" "unprognostic (1.68e-2)" "unprognostic (2.42e-3)" "unprognostic (5.39e-3)" 2.2 3.5 20.5 0.9 28.2 2.4 1.6 6.7 59.4 3.3 24.3 8.3 0.6 5.5 3.1 2.2 3.4 1.8 9.0 33.2 20.0 2.3 0.2 5.4 0.4 8.4 12.7 3.2 0.3 0.5 3.8 1.7 7.2 3.3 0.1 0.9 1.3 0.8 0.3 1.7 1.6 0.2 12.4 1.4 2.9 4.8 27.1 0.0 2.0 0.1 0.0 4.5 2.4 41.2 0.1 0.1 1.4 0.2 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.0 0.0 0.0 2.7 4.0 1.2 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 3.9 0.0 1.0 2.8 2.8 0.0 3.7 4.2 2.2 0.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 2.8 2.8 0.1 0.0 1.4 1.7 0.0 0.1 1.0 2.5 2.4 0.0 1.0 3.8 2.4 2.0 2.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 20.5 28.2 6.7 59.4 33.2 20.0 8.4 12.7 7.2 12.4 27.1 41.2 0.8 19.2 69.7 20.9 0.0 0.5 0.2 0.1 0.0 4.8 0.2 0.8 64.0 0.0 2.5 12.9 0.0 0.0 0.4 0.1 0.0 0.0 4.4 0.4 2.2 3.4 0.0 12.2 374.6 0.2 0.0 6.4 0.0 0.2 1.3 0.2 0.7 0.0 0.1 0.0 63.5 0.0 0.0 0.0 0.6 1.4 2.5 0.3 3.6 38.4 0.0 0.4 0.0 17.6 307.8 0.1 0.0 2.2 0.1 0.1 0.0 9.0 0.0 0.5 6.6 1.0 6.1 4.6 2.2 0.1 0.9 0.0 0.2 0.5 0.0 0.0 C8orf88 ENSG00000253250 "Chromosome 8 open reading frame 88" P0DMB2 8 90958471-90985238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 91.6" "Cell type enhanced" "Detected in many" "Early spermatids: 612.7;Late spermatids: 138.4;Spermatocytes: 329.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HHSteC: 63.4" "Low region specificity" "Detected in all" HPA078486 Enhanced NA NA "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA078486: " "unprognostic (2.17e-1)" "unprognostic (7.00e-2)" "unprognostic (2.51e-2)" "unprognostic (2.95e-4)" "unprognostic (4.07e-2)" "unprognostic (1.19e-1)" "unprognostic (8.44e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (4.90e-4)" "unprognostic (1.71e-2)" "unprognostic (9.89e-2)" "unprognostic (7.18e-2)" "unprognostic (6.04e-2)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (6.23e-6)" 8.0 3.8 2.2 4.2 2.9 11.0 6.7 2.4 2.7 10.6 4.9 32.9 2.1 21.4 13.1 8.7 11.9 7.1 38.2 2.2 3.2 4.9 1.0 4.7 1.7 3.0 2.6 13.3 1.3 0.4 4.1 3.5 3.0 13.9 5.7 1.6 2.4 23.5 1.4 7.1 6.5 30.8 3.2 3.0 13.3 91.6 2.7 13.0 10.9 1.8 1.4 19.0 7.8 4.3 0.1 2.4 13.4 1.2 15.4 13.4 0.2 14.6 22.8 19.8 29.7 0.1 3.8 0.3 1.3 14.9 20.6 0.1 0.2 1.1 36.7 0.0 38.6 41.7 11.5 0.0 63.4 0.0 1.3 14.1 0.3 22.3 37.0 28.9 2.1 13.6 25.0 23.9 30.3 0.0 39.7 14.9 3.3 0.0 0.7 0.0 26.1 0.1 16.3 0.1 11.4 19.8 0.6 0.0 19.6 15.1 0.0 1.9 8.5 22.8 38.0 0.3 15.5 33.3 33.4 21.2 22.6 0.0 10.5 0.0 0.0 0.0 0.9 0.0 1.2 1.1 0.8 1.0 0.2 0.9 0.7 1.4 0.0 3.8 0.0 3.2 0.6 0.4 2.2 2.9 2.4 2.7 2.2 3.2 3.0 2.6 3.0 3.2 2.7 4.3 6.4 0.0 1.1 1.3 2.9 18.9 9.3 1.0 19.4 0.0 0.5 8.6 12.4 2.8 0.1 3.7 0.0 0.2 0.8 0.0 5.9 1.1 612.7 0.3 9.0 4.7 0.0 55.6 3.1 0.0 0.9 13.7 0.0 0.2 2.5 4.9 5.0 0.0 0.6 0.0 6.4 0.0 0.0 0.8 3.8 138.4 19.0 1.7 10.6 1.9 0.6 0.9 0.0 2.0 4.0 3.6 0.0 21.8 3.0 6.6 0.0 1.4 0.1 0.2 19.7 8.2 21.1 329.5 30.7 6.9 26.6 0.0 2.8 2.0 0.0 1.2 PIP4P2 "DKFZp762O076, TMEM55A" ENSG00000155099 "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2" Q8N4L2 8 90993802-91040872 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 26.2;Cytotrophoblasts: 32.6;Distal tubular cells: 49.0;Extravillous trophoblasts: 31.1;Hofbauer cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 76.9" "Lineage enriched" "Detected in all" 7 "granulocytes: 76.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014591 Approved NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "HPA014591: AB_1858124" "unprognostic (6.09e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (8.45e-2)" "unprognostic (1.23e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.54e-4)" "prognostic unfavorable (3.76e-5)" "unprognostic (3.76e-2)" "unprognostic (1.08e-1)" "unprognostic (7.58e-2)" "unprognostic (4.42e-1)" "unprognostic (6.95e-2)" "unprognostic (7.25e-2)" "prognostic unfavorable (8.01e-4)" "unprognostic (1.59e-1)" "unprognostic (9.05e-2)" "unprognostic (7.99e-2)" 11.9 13.9 13.2 6.6 15.7 30.0 7.4 16.5 20.1 9.2 20.2 14.6 2.8 10.5 4.2 5.9 7.2 11.0 20.7 13.3 20.4 10.0 3.8 5.5 6.9 16.5 16.4 10.6 3.3 10.9 7.9 8.8 18.2 8.7 4.8 11.0 7.3 12.2 13.5 6.5 5.3 13.5 16.4 8.3 6.5 6.9 17.5 9.5 6.6 14.8 5.4 9.9 6.6 21.0 4.8 2.9 16.8 10.2 27.2 30.6 3.5 19.3 24.2 10.2 15.1 1.9 8.1 9.4 2.6 19.9 10.3 1.1 4.2 7.0 13.6 8.1 7.3 13.9 2.9 1.5 23.6 3.3 12.2 17.2 4.4 12.8 9.6 27.4 9.8 2.7 7.4 31.0 35.6 3.3 10.4 9.5 8.6 0.0 9.8 3.9 6.9 11.2 14.9 3.0 2.0 9.7 1.5 6.6 28.4 11.4 0.2 6.3 15.1 18.5 7.1 11.2 9.0 12.0 7.0 6.0 31.6 6.4 25.2 0.9 11.6 10.8 1.3 5.9 2.3 2.7 3.1 1.7 10.8 1.9 4.8 1.9 76.9 2.4 2.2 6.0 2.8 6.1 13.2 15.7 16.5 20.1 13.3 20.4 16.5 16.4 18.2 16.4 17.5 21.0 26.2 0.0 2.8 0.0 4.4 0.0 0.0 0.0 0.0 0.0 7.5 11.2 0.0 0.0 3.1 9.2 0.0 32.6 7.7 0.0 49.0 18.0 0.0 0.8 11.7 5.2 0.0 0.0 0.0 8.9 31.1 18.7 0.0 1.0 8.8 4.1 0.0 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.8 0.0 0.0 2.1 0.0 0.0 13.1 1.5 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 10.9 3.7 14.3 0.0 0.0 OTUD6B "CGI-77, DUBA5" ENSG00000155100 "OTU deubiquitinase 6B" Q8N6M0 8 91070196-91087095 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024046, HPA024503, HPA024772" Approved Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA024046: AB_10600925, HPA024503: AB_1854845, HPA024772: AB_1854846" "prognostic unfavorable (7.50e-4)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (4.78e-3)" "unprognostic (4.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-2)" "unprognostic (1.16e-3)" "unprognostic (2.17e-1)" "unprognostic (5.51e-2)" "unprognostic (1.27e-2)" "unprognostic (8.61e-3)" "unprognostic (1.87e-2)" "unprognostic (1.96e-1)" "unprognostic (4.53e-1)" "unprognostic (8.78e-2)" "unprognostic (5.71e-2)" 6.6 6.2 5.7 6.3 6.1 5.9 7.2 5.9 8.6 5.2 5.0 5.3 4.2 6.0 4.6 6.4 4.2 3.9 6.5 5.4 6.1 5.4 5.4 4.7 7.4 6.2 6.2 5.3 4.6 4.0 3.5 8.0 6.3 5.8 5.4 3.1 4.3 4.7 10.2 6.4 4.4 5.5 6.3 5.0 4.3 6.4 5.9 5.7 6.0 9.2 6.1 6.3 5.4 7.5 27.6 11.1 12.8 10.4 6.4 5.6 14.5 19.1 7.4 19.1 12.6 8.6 16.6 25.6 9.0 10.2 7.6 9.1 26.4 16.1 31.6 21.6 16.9 34.5 11.7 8.3 13.3 18.7 21.0 7.2 9.8 14.0 35.5 11.6 17.5 19.4 36.5 19.1 18.9 9.6 31.7 17.5 8.1 20.3 27.3 19.4 11.2 28.9 18.9 15.1 3.5 14.6 2.6 55.9 22.7 16.3 25.5 11.8 15.8 12.3 17.2 20.6 20.5 17.1 29.5 37.2 16.8 26.2 23.1 1.7 1.9 1.1 1.5 2.7 2.0 2.0 1.4 1.7 2.6 1.8 2.1 1.9 0.2 3.4 2.1 4.0 0.8 1.0 5.7 6.1 5.9 8.6 5.4 6.1 6.2 6.2 6.3 6.3 5.9 7.5 11.9 9.6 11.3 9.8 13.7 23.2 6.5 4.0 10.8 13.0 6.5 5.2 14.3 8.6 9.2 1.8 33.3 10.8 16.5 5.1 9.8 4.8 0.9 10.6 9.9 10.9 10.8 8.2 18.0 4.9 10.0 9.0 7.7 8.6 18.4 10.7 8.9 11.7 8.1 11.8 15.5 4.9 4.1 8.7 12.5 2.2 9.6 8.3 3.6 12.2 10.2 12.2 11.3 18.6 21.6 6.6 3.7 4.1 12.0 8.9 2.8 8.2 8.8 15.3 0.0 8.2 9.6 3.2 7.0 12.5 18.2 6.7 10.7 9.9 6.4 5.9 LRRC69 ENSG00000214954 "Leucine rich repeat containing 69" Q6ZNQ3 8 91101832-91219236 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in many" "Early spermatids: 77.3;Late spermatids: 18.0;Microglial cells: 27.2;Oligodendrocytes: 27.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.3;SuSa: 5.2;U-266/70: 16.0;U-266/84: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046337 Uncertain Approved "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA046337: AB_2679626" "unprognostic (1.63e-2)" "unprognostic (1.02e-1)" "unprognostic (4.69e-1)" "unprognostic (3.28e-1)" "unprognostic (2.78e-1)" "unprognostic (3.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.47e-1)" "unprognostic (9.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-6)" "unprognostic (6.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" "unprognostic (8.68e-5)" 0.3 0.5 0.2 0.9 0.6 0.1 0.6 0.6 0.4 0.3 0.8 0.3 0.2 0.2 0.9 0.3 0.2 0.4 0.5 0.2 0.4 0.5 0.3 0.4 1.1 0.8 0.5 0.2 0.3 0.9 0.2 0.4 0.8 0.5 0.7 0.6 0.7 0.3 0.5 1.7 0.4 0.8 0.5 0.7 0.4 2.9 0.5 0.8 0.5 0.4 0.7 0.7 0.3 1.0 0.6 0.6 0.1 0.4 0.6 1.3 1.0 0.3 0.1 0.2 0.3 0.9 0.8 0.9 0.4 0.2 0.1 0.6 0.7 1.1 0.3 0.3 6.3 1.4 1.8 0.4 0.2 0.5 1.0 0.4 1.0 0.4 0.7 0.4 0.1 1.1 1.0 0.5 0.4 0.2 0.3 0.4 0.6 1.0 0.4 0.8 0.0 0.7 0.2 0.7 0.0 0.2 0.0 0.4 1.0 5.2 1.4 1.0 0.5 0.2 0.6 0.1 0.8 16.0 9.5 3.8 0.1 2.1 0.8 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.3 0.1 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.4 0.5 0.0 0.2 0.6 0.6 0.4 0.2 0.4 0.8 0.5 0.8 0.5 0.5 1.0 1.1 0.0 1.1 16.0 1.5 4.7 2.9 1.3 0.6 1.9 1.6 0.6 2.9 0.0 1.5 3.7 4.2 2.3 2.0 1.1 3.9 1.5 77.3 1.2 0.4 2.7 2.4 0.8 5.3 1.2 1.9 1.7 0.0 0.6 0.0 1.0 4.2 0.6 0.9 0.0 6.4 2.2 6.1 1.3 7.0 18.0 2.8 1.6 7.2 27.2 4.2 1.1 2.1 7.5 27.9 1.8 1.6 1.2 0.2 5.3 0.4 0.9 6.1 3.2 0.0 4.7 2.7 4.2 4.0 0.7 5.3 1.0 2.2 0.9 1.7 2.3 SLC26A7 SUT2 ENSG00000147606 "Solute carrier family 26 member 7" Q8TE54 8 91209494-91398155 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 330.3" "Cell type enhanced" "Detected in some" "Collecting duct cells: 23.9;Endometrial ciliated cells: 31.6;Endometrial stromal cells: 23.9;Enteroendocrine cells: 45.2;Glandular and luminal cells: 52.0;Hepatic stellate cells: 24.7" "Group enriched" "Detected in some" 11 "renal cancer: 8.7;thyroid cancer: 32.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 44: Endometrium - Transcription" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (8.04e-3)" "unprognostic (4.15e-3)" "unprognostic (1.51e-1)" "unprognostic (2.39e-3)" "unprognostic (2.94e-3)" "unprognostic (1.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.41e-2)" "unprognostic (8.26e-2)" "unprognostic (4.82e-2)" "unprognostic (3.31e-2)" "unprognostic (2.07e-1)" "unprognostic (5.19e-3)" "unprognostic (6.83e-3)" 1.5 0.1 0.1 0.0 0.2 0.0 0.3 0.2 0.1 1.4 0.2 0.2 0.1 2.7 0.1 0.0 0.5 0.6 0.7 0.0 0.1 23.8 0.0 0.1 3.7 0.1 0.1 0.1 1.2 0.2 0.3 0.3 0.2 0.1 0.4 0.0 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 6.1 0.5 0.2 0.0 330.3 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.2 0.4 3.9 0.0 1.5 5.9 0.1 0.3 0.4 0.2 0.0 0.0 1.9 0.6 1.1 0.0 0.3 23.9 0.0 0.0 0.0 0.3 13.7 0.1 11.9 31.6 23.9 1.5 45.2 0.0 0.5 0.2 0.0 1.5 1.5 52.0 0.0 0.1 24.7 0.1 0.1 0.0 0.7 0.7 2.0 0.6 0.3 2.9 3.7 0.2 3.6 0.0 0.0 0.1 0.0 0.0 3.8 1.4 0.2 0.0 0.0 0.3 0.0 0.3 1.9 0.2 0.0 0.0 4.4 0.6 1.1 0.0 0.1 0.0 0.4 0.5 0.3 0.1 RUNX1T1 "AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2" ENSG00000079102 "RUNX1 partner transcriptional co-repressor 1" Q06455 8 91954967-92103286 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 93.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 142.1;Excitatory neurons: 196.9;Hepatic stellate cells: 124.2;Inhibitory neurons: 326.3;Oligodendrocyte precursor cells: 262.4" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in all" 7 "cerebellum: 93.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 19.6;fHDF/TERT166: 16.5;HEL: 35.9;HSkMC: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049852, HPA070951" Approved Supported Nucleoplasm NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA049852: AB_2680914, HPA070951: AB_2686326" "unprognostic (2.37e-1)" "unprognostic (1.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.37e-4)" "unprognostic (2.29e-4)" "unprognostic (5.56e-3)" "unprognostic (1.24e-2)" "unprognostic (1.62e-2)" "unprognostic (2.11e-2)" "unprognostic (2.37e-1)" "unprognostic (5.70e-4)" "unprognostic (8.98e-3)" "unprognostic (6.78e-2)" "unprognostic (1.51e-1)" "unprognostic (7.80e-3)" 7.0 2.8 9.4 2.1 13.2 0.2 5.1 93.1 8.7 8.4 0.0 6.5 1.2 7.4 3.6 2.5 4.7 5.0 8.2 13.1 2.3 1.4 0.6 3.8 1.3 1.4 12.8 4.7 1.0 1.0 3.0 5.8 4.6 2.5 2.4 5.2 3.1 2.4 3.9 2.4 2.5 6.5 4.2 1.9 2.7 3.6 3.6 0.5 3.7 4.8 1.1 3.8 3.9 1.2 0.0 0.0 0.4 1.9 5.0 7.2 0.0 7.6 11.6 5.0 7.6 0.0 0.0 19.6 0.0 16.5 0.0 0.0 4.0 0.5 3.3 0.0 3.2 35.9 0.0 0.0 1.9 0.0 0.0 13.6 0.0 8.4 0.4 0.0 10.8 0.0 0.1 0.0 1.3 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 11.1 6.0 0.0 0.0 0.0 7.8 0.0 0.0 1.2 0.4 0.0 0.9 0.0 3.8 0.0 6.3 0.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 13.2 93.1 8.7 13.1 2.3 1.4 12.8 4.6 4.2 3.6 1.2 44.9 0.0 1.1 90.8 0.1 6.2 0.2 0.0 0.6 142.1 1.2 5.1 46.0 0.0 0.6 0.0 16.7 1.1 0.5 0.2 1.9 0.0 2.6 1.1 65.8 64.3 47.7 2.7 196.9 0.2 0.3 77.7 0.5 1.1 1.3 2.1 124.2 1.5 1.9 35.3 326.3 0.6 0.0 4.1 9.4 7.5 96.3 1.2 10.6 103.0 0.0 3.9 0.0 262.4 17.3 0.2 0.0 98.9 0.0 0.3 0.0 0.1 0.0 7.2 65.7 24.4 43.1 3.3 16.8 0.9 4.8 1.1 1.1 20.7 0.0 0.1 TRIQK "C8orf83, DKFZp779L1068, LOC286144, PRO0845" ENSG00000205133 "Triple QxxK/R motif containing" Q629K1 8 92883532-93017673 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 32.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (3.47e-3)" "unprognostic (3.09e-1)" "unprognostic (6.03e-3)" "unprognostic (4.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.21e-1)" "unprognostic (5.13e-2)" "unprognostic (7.78e-2)" "unprognostic (2.50e-1)" "unprognostic (2.31e-1)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "unprognostic (1.79e-1)" "unprognostic (5.11e-3)" "unprognostic (9.23e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-2)" 12.8 21.9 12.3 7.7 15.7 14.5 14.5 18.6 14.9 19.4 10.5 20.7 12.4 12.5 9.7 9.8 15.7 22.9 20.1 13.7 13.5 19.4 31.3 17.0 5.3 13.4 12.6 19.6 18.0 20.6 10.7 19.6 14.0 18.1 21.0 12.4 11.1 10.2 2.4 5.7 12.1 11.4 14.2 13.2 17.5 6.5 13.5 7.3 23.4 5.6 5.2 15.5 7.9 17.0 7.4 9.2 19.8 7.0 27.1 42.8 6.6 26.4 28.4 14.7 20.9 1.3 22.9 0.0 31.6 24.9 9.8 11.9 16.1 15.9 23.7 0.0 7.6 28.9 10.1 15.6 22.9 8.1 24.0 32.0 35.4 8.0 27.1 33.3 15.7 16.3 5.6 16.7 21.3 19.7 13.1 6.3 6.8 31.3 33.8 0.0 20.5 9.6 27.8 9.1 11.4 16.0 10.0 3.9 25.6 16.3 27.2 7.1 20.5 21.8 6.7 38.3 8.3 5.8 0.0 0.0 33.8 0.1 22.5 0.9 17.0 15.9 0.1 18.8 8.1 2.8 0.9 0.7 9.4 1.9 0.0 0.0 14.6 2.0 32.9 2.5 0.2 4.7 12.3 15.7 18.6 14.9 13.7 13.5 13.4 12.6 14.0 14.2 13.5 17.0 19.0 19.2 17.9 21.9 4.0 15.0 21.4 17.1 22.8 18.9 17.7 12.4 13.8 25.8 14.1 16.5 6.2 7.3 2.1 16.2 50.9 14.8 7.0 21.3 27.7 17.8 19.2 6.7 36.8 16.4 23.8 23.5 20.9 24.5 2.5 11.7 17.2 18.3 11.9 6.7 43.6 35.6 12.2 20.0 13.6 8.0 16.4 18.5 23.2 31.9 24.3 22.8 3.1 34.7 56.3 12.5 14.0 21.8 1.0 22.2 17.0 39.1 29.5 6.3 32.9 18.4 18.2 12.1 5.3 12.3 8.4 3.7 3.3 21.6 20.0 22.6 CIBAR1 "FAM92A, FAM92A1, FLJ38979" ENSG00000188343 "CBY1 interacting BAR domain containing 1" A1XBS5 8 93698561-93731527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 110.2" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Extravillous trophoblasts: 14.1;Fibroblasts: 8.4;Hofbauer cells: 6.4;Syncytiotrophoblasts: 3.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034760, HPA058942" Enhanced Approved Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Mitochondria "HPA034760: AB_10599947, HPA058942: AB_2732628" "unprognostic (2.65e-3)" "unprognostic (6.81e-2)" "unprognostic (2.48e-3)" "unprognostic (2.44e-1)" "unprognostic (1.62e-2)" "unprognostic (2.93e-1)" "unprognostic (3.56e-1)" "unprognostic (3.13e-1)" "unprognostic (1.20e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (6.85e-3)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" 14.3 23.9 17.5 5.6 18.8 3.5 10.9 18.6 25.0 16.5 22.9 14.2 3.2 16.0 26.2 5.0 13.1 14.1 25.3 17.8 16.2 20.2 18.5 9.9 5.7 13.4 14.5 18.0 21.1 21.5 20.8 10.1 13.3 12.1 5.9 14.1 5.7 11.6 10.3 6.6 7.7 15.0 12.9 5.7 9.8 110.2 17.1 5.0 14.5 11.1 3.1 14.6 9.3 17.4 37.8 20.0 52.9 54.6 55.8 78.9 14.0 34.2 49.8 45.2 43.5 3.5 8.6 3.2 42.7 50.7 52.0 26.6 54.0 32.5 41.0 1.2 29.5 21.5 20.8 18.7 64.1 1.0 5.5 50.4 14.3 44.3 36.0 64.9 49.0 18.1 13.4 1.7 35.8 14.2 23.8 4.1 22.2 0.8 1.1 2.3 39.7 0.8 35.3 8.7 15.3 18.7 24.4 0.5 41.6 23.7 8.2 11.8 27.2 44.2 17.4 46.3 28.0 2.6 2.7 1.2 38.8 3.0 15.8 0.1 1.7 0.0 0.1 1.2 0.2 0.4 0.4 0.1 2.9 0.0 0.1 0.3 0.0 1.3 0.1 0.3 0.8 0.5 17.5 18.8 18.6 25.0 17.8 16.2 13.4 14.5 13.3 12.9 17.1 17.4 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 14.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 RBM12B ENSG00000183808 "RNA binding motif protein 12B" Q8IXT5 8 93729356-93741017 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024398, HPA053050" Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA024398: AB_1856109, HPA053050: AB_2682026" "unprognostic (4.57e-2)" "unprognostic (7.72e-2)" "unprognostic (3.39e-1)" "unprognostic (3.57e-2)" "unprognostic (1.78e-1)" "unprognostic (2.66e-2)" "unprognostic (2.40e-3)" "unprognostic (3.05e-1)" "unprognostic (3.92e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "unprognostic (2.54e-2)" "unprognostic (1.84e-3)" "unprognostic (9.15e-2)" "unprognostic (4.82e-1)" "unprognostic (4.34e-2)" "unprognostic (2.62e-2)" 6.6 7.2 3.2 14.8 4.3 9.2 11.7 15.2 5.2 11.4 3.5 8.9 9.1 14.3 8.9 8.5 11.7 8.4 9.3 3.1 6.6 8.9 6.4 8.5 19.8 4.0 2.1 21.8 7.8 9.4 5.6 13.4 2.8 13.0 9.4 24.7 10.2 8.4 5.5 8.5 9.0 8.3 1.5 13.6 10.6 17.6 2.5 16.3 15.9 6.2 16.9 8.4 7.1 10.8 26.0 19.3 48.3 34.4 11.7 22.3 23.4 21.4 15.8 23.9 24.9 14.6 34.6 45.5 33.2 12.0 25.4 26.0 42.3 11.3 26.7 32.3 21.8 59.0 48.2 12.6 13.7 22.2 28.7 14.6 14.2 15.7 15.5 15.8 16.4 26.6 49.4 37.0 21.3 15.0 41.3 17.3 0.2 19.6 20.4 30.2 34.2 15.0 12.3 21.9 31.6 25.0 23.0 7.2 17.8 33.0 27.5 16.7 32.0 22.2 33.3 16.3 22.3 43.0 34.2 38.3 15.8 31.0 38.0 15.0 2.3 4.4 2.3 2.0 3.5 1.5 3.0 2.4 2.2 2.1 4.1 3.5 3.3 3.0 2.4 2.9 3.8 2.1 3.2 4.3 15.2 5.2 3.1 6.6 4.0 2.1 2.8 1.5 2.5 10.8 16.8 6.4 8.1 23.2 17.9 4.0 7.1 7.2 11.4 31.8 9.9 9.1 11.8 10.0 6.6 12.9 43.8 7.9 13.7 5.5 3.9 6.9 1.4 11.3 21.4 12.8 15.7 17.7 23.7 4.8 4.8 13.5 7.7 12.8 0.0 30.3 11.4 8.4 4.7 45.4 26.6 9.2 8.2 11.1 5.8 2.4 12.5 8.9 5.4 21.5 15.9 21.9 17.5 32.6 40.2 6.8 7.1 10.1 8.7 8.8 5.9 5.0 12.5 32.1 19.7 23.2 13.1 19.1 10.9 7.3 4.3 4.0 11.8 13.5 8.0 4.9 TMEM67 "JBTS6, MGC26979, MKS3, NPHP11" ENSG00000164953 "Transmembrane protein 67" Q5HYA8 8 93754844-93819234 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Deafness, Disease variant, Joubert syndrome, Meckel syndrome, Mental retardation, Nephronophthisis, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7;Excitatory neurons: 59.8;Respiratory ciliated cells: 95.8;Rod photoreceptor cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.57e-3)" "unprognostic (1.22e-1)" "unprognostic (2.45e-2)" "unprognostic (1.73e-1)" "unprognostic (5.07e-2)" "unprognostic (3.08e-1)" "unprognostic (2.25e-5)" "unprognostic (2.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.51e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (7.62e-4)" "unprognostic (8.41e-2)" "unprognostic (2.21e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" 2.4 2.5 1.7 1.3 2.7 1.4 3.5 2.8 2.7 3.6 10.3 2.1 1.4 4.2 6.3 1.8 13.3 2.8 5.0 2.5 3.0 3.1 1.2 3.6 1.4 6.5 6.8 4.2 2.6 4.7 5.8 2.1 3.1 2.8 2.2 6.1 1.9 3.2 1.2 3.7 1.3 2.4 3.5 1.9 2.0 6.8 3.1 1.4 6.0 0.6 1.7 2.5 2.2 3.9 5.8 3.7 5.2 4.1 4.4 9.8 3.1 3.3 5.4 3.8 7.5 2.1 13.0 1.5 6.9 3.6 6.9 5.9 1.9 3.3 5.6 1.1 4.3 3.6 4.8 1.8 4.0 2.7 1.5 4.2 3.0 6.8 3.0 7.1 4.0 6.1 2.5 0.9 4.0 1.4 4.5 2.0 4.3 2.3 3.4 1.6 1.7 0.0 4.7 2.5 3.4 5.7 3.3 0.9 5.6 4.6 6.8 1.4 2.1 4.1 1.7 5.7 3.0 1.8 5.5 1.6 7.4 0.8 3.9 1.7 0.5 0.2 1.5 0.2 1.2 0.7 1.3 1.3 1.0 1.5 1.5 1.5 0.5 1.8 0.2 1.1 0.3 0.5 1.7 2.7 2.8 2.7 2.5 3.0 6.5 6.8 3.1 3.5 3.1 3.9 5.0 12.8 8.7 27.4 6.3 2.8 5.6 12.2 2.2 14.6 6.0 5.6 31.9 5.7 12.5 20.2 66.7 3.4 5.6 1.2 0.0 6.4 24.5 50.9 15.1 6.8 9.0 4.6 59.8 2.7 5.6 9.8 4.1 4.9 5.1 16.1 10.0 1.6 2.2 23.5 34.2 2.4 8.2 2.9 2.6 7.7 16.1 1.8 1.8 13.1 1.5 9.3 3.1 17.6 3.4 2.1 0.5 10.5 2.7 2.1 0.4 3.9 95.8 83.2 6.6 18.9 6.9 47.6 16.5 2.6 1.4 2.3 5.6 13.7 2.8 1.6 PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehyrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 80.0;Early spermatids: 144.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 8 "amygdala: 14.2;basal ganglia: 20.1;cerebral cortex: 41.7;hippocampal formation: 23.4;white matter: 18.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 117.8;hTERT-RPE1: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Approved Nucleoplasm,Mitochondria,Cytosol Yes No "Cluster 27: Non-specific - Gene expression" "Cluster 8: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria, Cytosol" "HPA018483: AB_1855634, HPA019081: AB_1855633, HPA021152: AB_1855635" "prognostic unfavorable (8.61e-5)" "unprognostic (4.62e-1)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.46e-2)" "unprognostic (1.38e-1)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.71e-2)" "unprognostic (3.25e-1)" "prognostic favorable (8.42e-9)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (5.04e-2)" "unprognostic (1.67e-1)" 10.6 62.6 14.2 10.5 20.1 14.4 16.1 0.0 41.7 14.2 1.2 8.9 7.2 15.5 17.0 14.2 12.2 19.4 49.2 23.4 0.0 12.8 4.2 12.6 12.9 0.0 2.3 19.3 19.9 29.9 5.4 13.8 0.0 10.3 12.4 14.1 11.7 9.4 72.9 4.3 7.6 11.2 0.0 13.2 11.7 26.7 3.0 11.6 18.8 16.9 12.4 14.0 6.8 18.5 25.7 12.0 25.9 10.9 21.0 37.9 8.6 19.3 21.7 22.1 25.8 12.7 90.3 13.9 63.8 30.8 117.8 54.4 11.0 16.1 32.8 1.5 5.6 6.6 15.7 4.5 23.9 3.3 9.0 24.5 31.5 37.7 59.8 117.1 50.9 12.4 2.4 22.8 27.6 6.0 20.3 10.3 12.1 26.8 15.4 4.8 15.5 2.6 15.3 17.0 2.4 11.4 12.7 1.4 61.8 20.9 4.0 3.9 90.9 27.5 17.2 63.8 23.3 12.6 5.8 12.1 34.2 11.7 25.1 6.4 27.9 14.5 9.2 25.3 8.9 15.6 15.1 12.0 22.5 17.9 8.9 7.8 3.1 5.4 41.1 3.7 34.9 18.0 14.2 20.1 0.0 41.7 23.4 0.0 0.0 2.3 0.0 0.0 3.0 18.5 10.7 12.8 7.8 15.0 18.0 13.0 12.7 36.3 68.9 38.3 11.6 7.0 80.0 14.3 35.6 16.5 8.4 4.3 13.7 27.5 5.9 33.3 144.2 33.3 14.9 15.0 10.2 1.3 73.6 14.0 3.9 20.8 16.3 70.2 6.3 3.7 12.5 3.3 6.3 10.1 23.4 5.5 10.2 19.2 19.1 28.1 11.5 19.9 10.6 19.7 22.4 18.8 10.3 13.0 8.5 24.5 9.6 13.5 8.1 15.6 4.9 11.4 30.5 11.5 6.6 35.4 13.1 10.1 11.4 26.5 10.9 4.4 19.3 7.1 10.7 23.9 CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 569.4;Enteroendocrine cells: 108.4;Intestinal goblet cells: 183.7;Paneth cells: 408.6;Proximal enterocytes: 336.9;Undifferentiated cells: 241.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Cell line enhanced" "Detected in some" "CACO-2: 98.8;OE19: 430.1;U-266/70: 157.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" 0.9 0.2 0.7 28.8 0.5 2.7 0.5 1.1 0.8 0.1 1.9 260.9 314.2 1.3 0.8 1.7 0.3 3.0 0.6 0.5 0.2 0.8 0.3 0.2 1.5 0.3 0.1 0.5 1.7 0.0 0.0 0.2 0.3 1.2 246.7 0.5 0.9 1.6 0.5 0.6 270.6 9.3 0.1 5.5 2.5 0.6 0.2 0.3 0.7 0.1 1.8 0.8 0.1 0.7 0.2 18.5 0.2 0.4 0.0 0.4 1.6 0.2 0.3 0.2 0.3 98.8 3.5 0.3 0.3 0.0 0.1 1.0 0.3 0.3 0.3 0.2 1.1 0.1 0.8 0.6 0.3 0.2 4.3 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.4 1.5 0.1 0.7 0.5 1.3 0.3 430.1 0.5 0.3 0.0 2.8 0.3 0.2 1.3 1.2 0.4 0.4 0.5 0.4 0.7 0.9 0.0 0.6 0.7 1.2 0.5 157.2 0.3 0.2 0.3 0.3 0.6 2.9 0.9 1.4 0.2 0.8 0.1 0.3 0.2 0.1 0.5 0.8 0.2 0.3 16.0 0.7 0.5 0.4 0.2 0.2 0.7 0.5 1.1 0.8 0.5 0.2 0.3 0.1 0.3 0.1 0.2 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 569.4 0.0 0.3 1.0 0.0 0.0 0.0 108.4 0.0 0.5 0.0 0.0 0.1 2.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 183.7 0.0 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 408.6 0.0 0.2 0.0 336.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 2.1 0.0 241.6 0.1 GEM KIR ENSG00000164949 "GTP binding protein overexpressed in skeletal muscle" P55040 8 94249253-94262350 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 229.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 721.1;Fibroblasts: 395.9;Langerhans cells: 155.5;Smooth muscle cells: 359.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BJ hTERT+: 83.0;U-266/70: 140.6;U-87 MG: 104.7" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "spinal cord: 24.3" HPA024798 Approved NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA024798: AB_10602137" "unprognostic (1.24e-1)" "unprognostic (2.12e-1)" "unprognostic (4.82e-3)" "unprognostic (1.22e-1)" "unprognostic (4.76e-1)" "unprognostic (3.94e-1)" "unprognostic (2.17e-1)" "unprognostic (4.00e-1)" "unprognostic (1.45e-1)" "unprognostic (9.04e-2)" "unprognostic (7.92e-2)" "unprognostic (9.15e-2)" "prognostic unfavorable (1.56e-5)" "unprognostic (1.65e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.93e-3)" 56.1 58.4 10.9 35.6 9.6 2.6 36.7 8.3 12.3 57.9 38.7 105.7 16.6 97.2 9.7 59.5 39.0 229.6 63.4 11.0 20.8 32.3 20.2 33.1 23.8 12.7 12.2 19.9 15.7 2.9 27.3 7.3 11.0 31.7 35.9 44.4 13.1 16.8 4.2 10.9 31.1 77.3 8.4 21.9 48.0 3.8 12.2 12.6 23.6 10.8 14.2 90.6 33.6 12.3 1.6 6.1 2.7 0.6 22.9 30.4 0.4 16.1 83.0 21.4 29.8 2.3 4.1 0.0 1.0 6.1 40.1 0.5 2.7 1.4 28.0 12.2 1.4 0.0 0.6 0.0 3.0 0.0 26.3 13.1 0.1 34.1 18.9 24.4 0.9 1.4 0.7 2.7 12.7 0.8 1.0 0.2 4.0 3.4 18.3 0.0 4.9 0.1 7.8 0.0 20.4 12.1 0.0 0.1 2.8 3.4 2.0 0.1 1.2 29.4 8.1 19.2 33.4 140.6 0.9 0.1 104.7 0.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 10.9 9.6 8.3 12.3 11.0 20.8 12.7 12.2 11.0 8.4 12.2 12.3 18.4 6.4 25.4 22.2 8.9 68.1 85.7 9.6 721.1 26.8 8.6 35.1 90.8 4.3 4.0 1.8 18.8 0.4 4.1 8.2 0.0 7.3 4.7 26.0 49.2 19.0 25.0 0.0 0.7 0.4 1.4 395.9 54.0 50.3 13.4 1.0 7.1 0.1 2.8 30.3 3.4 2.6 2.0 0.6 155.5 0.3 3.4 43.3 92.5 0.0 0.8 41.9 0.0 0.0 0.3 2.7 17.2 5.7 46.5 20.2 2.1 2.6 1.2 21.4 32.9 55.5 359.5 1.3 1.1 24.1 49.9 3.4 33.4 0.9 4.2 10.6 RAD54B RDH54 ENSG00000197275 "RAD54 homolog B" Q9Y620 8 94371960-94475115 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.0" "Cell type enhanced" "Detected in many" "Astrocytes: 29.0;Cone photoreceptor cells: 27.1;Excitatory neurons: 45.8;Inhibitory neurons: 19.0;Oligodendrocyte precursor cells: 39.7;Oligodendrocytes: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.9" "Group enriched" "Detected in many" 10 "B-cells: 1.0;T-cells: 1.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA007087 Enhanced NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA007087: AB_1856040" "unprognostic (1.68e-3)" "unprognostic (2.51e-1)" "unprognostic (2.31e-2)" "unprognostic (8.84e-3)" "unprognostic (4.15e-2)" "unprognostic (1.44e-1)" "unprognostic (5.56e-8)" "unprognostic (1.96e-2)" "unprognostic (1.77e-2)" "unprognostic (5.39e-2)" "unprognostic (2.30e-2)" "unprognostic (2.64e-1)" "unprognostic (2.04e-12)" "unprognostic (5.86e-2)" "unprognostic (5.23e-1)" "unprognostic (9.08e-2)" "unprognostic (6.68e-5)" 0.6 0.7 1.3 1.7 2.0 2.0 1.9 2.1 2.1 2.4 1.7 1.5 1.4 1.1 2.1 1.4 5.0 0.7 0.6 1.2 1.6 0.8 1.4 0.7 2.7 1.6 1.9 1.0 0.8 0.7 1.2 1.4 1.6 1.6 2.1 7.0 0.8 2.0 0.3 1.8 1.2 1.1 1.3 0.9 1.5 3.6 1.7 4.2 1.1 0.3 3.0 1.2 0.9 1.6 20.5 15.7 20.9 11.2 1.6 2.5 11.0 16.2 8.9 22.7 23.1 8.1 14.8 14.5 25.3 4.3 11.7 12.7 18.7 7.7 24.6 17.5 11.9 23.2 8.1 7.7 1.5 8.4 8.5 0.8 1.8 11.7 14.9 4.5 8.3 14.7 16.6 8.9 24.6 10.6 28.5 5.7 13.5 23.4 14.4 7.1 21.3 8.7 8.9 9.8 12.0 8.0 11.6 2.8 9.7 17.9 14.9 6.1 5.8 14.8 7.6 16.7 18.1 4.5 12.2 7.8 7.7 15.9 15.4 0.0 0.0 0.0 0.5 0.0 1.9 0.7 0.9 0.4 0.0 1.0 0.8 1.1 0.0 0.1 0.1 0.0 0.6 0.3 1.3 2.0 2.1 2.1 1.2 1.6 1.6 1.9 1.6 1.3 1.7 1.6 0.5 0.0 0.5 29.0 1.7 0.4 0.9 1.7 1.2 9.1 1.1 1.1 1.8 1.5 0.6 3.7 27.1 2.0 0.5 0.7 1.9 0.8 0.3 11.5 1.6 1.3 1.2 3.8 45.8 0.8 3.2 1.3 3.1 5.6 0.0 3.3 3.3 2.0 1.5 0.0 19.0 1.1 0.0 0.6 0.6 0.4 3.4 0.9 0.0 9.4 0.6 4.4 1.0 39.7 25.9 0.7 0.4 2.2 3.9 0.4 0.2 1.4 3.3 17.5 0.0 1.0 1.7 9.4 13.1 3.7 0.6 0.3 2.6 3.0 2.3 0.7 FSBP ENSG00000265817 "Fibrinogen silencer binding protein" O95073 8 94378377-94436952 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 12.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Endometrial ciliated cells: 15.3;Glandular and luminal cells: 6.2;Rod photoreceptor cells: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025059, HPA026509" Approved Supported Nucleoplasm NA NA "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA025059: AB_2671718, HPA026509: AB_10602307" 0.7 1.0 1.2 0.5 1.5 1.4 1.4 1.6 1.7 1.7 3.7 0.6 0.6 1.5 2.6 1.1 1.6 0.9 1.3 0.9 1.2 1.0 1.2 0.7 0.9 1.2 2.3 2.7 1.0 1.1 1.6 0.9 1.0 1.9 0.7 12.0 1.1 2.1 1.3 1.5 0.7 0.8 1.3 0.8 1.4 1.8 1.8 1.2 1.1 0.6 0.8 1.5 1.1 1.3 3.7 1.7 7.6 3.8 1.1 1.3 1.3 1.4 1.4 1.5 1.3 1.9 1.9 2.6 4.1 1.1 1.2 0.9 4.7 2.4 2.6 2.6 1.8 2.9 1.4 1.6 3.3 1.9 0.8 2.4 0.5 2.1 6.4 2.5 2.4 9.0 4.5 4.4 1.4 2.4 6.6 2.3 4.9 1.4 1.1 1.4 4.4 2.5 4.0 5.1 2.5 3.0 0.9 0.3 4.6 5.9 2.5 0.7 2.1 3.0 1.3 1.6 1.5 1.3 1.9 1.3 1.8 2.8 3.4 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 1.2 1.5 1.6 1.7 0.9 1.2 1.2 2.3 1.0 1.3 1.8 1.3 0.6 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.6 1.1 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 15.3 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.5 2.0 6.2 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 0.5 0.9 0.0 0.0 VIRMA "DKFZP434I116, fSAP121, KIAA1429" ENSG00000164944 "Vir like m6A methyltransferase associated" Q69YN4 8 94487689-94553529 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 26.4;Endometrial stromal cells: 32.2;Granulosa cells: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031530 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear bodies" Nucleoplasm "HPA031530: AB_10600818" "unprognostic (2.51e-2)" "unprognostic (7.41e-3)" "unprognostic (3.43e-1)" "unprognostic (3.83e-3)" "unprognostic (1.83e-1)" "unprognostic (7.83e-2)" "unprognostic (7.54e-3)" "unprognostic (1.98e-3)" "unprognostic (1.27e-1)" "unprognostic (2.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.74e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (2.48e-1)" "unprognostic (1.68e-1)" "unprognostic (3.82e-2)" "unprognostic (9.87e-2)" 12.5 7.8 6.9 11.6 8.5 27.3 17.5 11.5 7.2 13.1 7.1 9.9 8.1 13.7 8.6 9.7 11.4 8.9 9.9 6.1 7.4 10.8 12.5 10.7 14.4 7.1 7.2 16.7 10.3 14.8 6.3 13.2 7.2 10.7 11.7 12.3 9.5 10.3 8.7 9.7 9.1 13.9 7.2 11.4 11.6 16.5 7.3 20.0 13.3 9.3 15.2 10.5 8.0 9.2 40.5 25.2 26.8 14.9 32.4 42.5 17.1 27.5 27.9 29.4 29.9 17.9 33.2 43.6 25.5 36.1 23.0 25.9 36.2 33.5 42.9 38.7 20.0 52.0 19.6 17.6 23.6 25.9 17.9 32.8 13.4 35.4 33.7 30.1 37.5 28.2 54.0 26.6 30.0 23.8 50.7 14.6 17.5 41.4 19.1 29.9 24.4 24.3 19.1 27.6 20.9 28.9 21.6 5.5 23.8 26.3 31.2 20.7 37.3 26.9 15.9 23.1 25.7 20.8 27.8 51.0 26.4 33.7 26.2 14.2 5.0 8.7 6.7 6.4 10.7 6.6 7.4 9.1 5.2 5.0 9.0 7.9 6.0 9.5 13.8 3.3 6.9 5.8 6.9 8.5 11.5 7.2 6.1 7.4 7.1 7.2 7.2 7.2 7.3 9.2 24.2 25.6 21.5 0.0 6.3 0.0 0.0 0.0 0.0 0.0 16.9 16.4 0.0 0.0 14.9 7.3 0.0 26.4 20.0 0.0 7.9 14.4 0.0 23.8 32.2 9.8 0.0 0.0 0.0 12.2 23.7 10.6 0.0 22.4 5.1 28.5 0.0 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 14.7 0.0 0.0 5.2 0.0 0.0 6.9 8.7 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 16.8 9.9 25.0 0.0 0.0 ESRP1 "FLJ20171, RBM35A" ENSG00000104413 "Epithelial splicing regulatory protein 1" Q6NXG1 8 94641074-94707466 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Intestinal goblet cells: 107.2;Suprabasal keratinocytes: 79.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 138.3;BEWO: 101.1;CAPAN-2: 140.8;hTCEpi: 226.5;OE19: 142.6;RT4: 99.1;T-47d: 108.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023719, HPA023720, HPA067104" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" Nucleoplasm "HPA023719: AB_1856124, HPA023720: AB_1856125, HPA067104: AB_2685779" "prognostic unfavorable (9.28e-4)" "unprognostic (7.12e-2)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.56e-4)" "unprognostic (4.12e-1)" "unprognostic (6.99e-3)" "unprognostic (2.70e-1)" "unprognostic (2.61e-2)" "unprognostic (5.19e-2)" "unprognostic (5.51e-2)" "prognostic unfavorable (2.05e-4)" "unprognostic (4.48e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.96e-2)" "unprognostic (1.29e-1)" 0.2 0.0 0.0 5.2 0.0 0.0 24.2 0.0 0.0 15.5 0.0 57.1 25.2 3.4 29.6 64.2 21.3 8.5 0.1 0.0 0.0 8.5 0.4 15.8 0.0 0.0 0.1 0.1 42.6 28.4 7.2 12.2 0.0 19.9 62.8 0.0 25.9 10.0 0.1 60.6 22.0 2.5 0.0 0.0 38.6 0.6 0.4 5.2 36.6 0.0 15.3 22.5 28.8 0.0 138.3 0.0 0.0 0.2 0.0 0.0 101.1 0.0 0.0 0.0 0.0 44.6 140.8 0.0 3.8 0.0 0.1 81.6 3.8 70.9 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 226.5 0.0 1.4 0.0 0.0 10.7 0.0 0.0 0.0 67.3 1.9 0.4 12.4 142.6 3.4 0.0 0.0 18.3 17.4 99.1 35.1 0.3 0.0 21.0 14.0 21.4 108.0 0.9 0.0 0.1 0.2 0.1 0.3 12.0 13.8 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 38.5 36.7 0.0 0.6 44.6 18.9 30.4 35.9 0.0 29.4 18.0 1.0 21.5 32.4 27.6 0.0 55.1 0.5 76.2 13.7 19.6 12.9 47.1 3.7 0.9 33.1 0.0 2.6 27.5 69.1 0.9 58.1 46.5 1.3 0.0 0.4 0.1 6.0 0.0 0.4 107.2 16.2 0.0 3.2 10.3 0.0 0.5 24.9 0.0 0.6 0.0 0.0 0.5 0.4 21.7 48.1 0.7 1.8 25.1 25.5 0.3 35.0 0.0 0.0 0.0 1.2 0.6 0.9 71.3 79.1 62.1 0.8 0.0 73.9 40.1 DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024339, HPA024780" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA024339: , HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" 11.5 12.3 7.3 6.6 10.5 5.1 12.5 9.7 9.4 13.6 8.0 8.6 6.7 12.3 10.5 7.6 11.2 10.0 15.4 6.5 10.1 14.5 15.8 9.1 6.9 9.9 9.0 16.7 9.4 26.4 6.4 12.6 10.3 11.6 9.0 13.0 10.2 9.0 7.2 9.4 7.9 9.5 9.6 11.1 13.1 9.6 8.9 7.0 16.1 9.3 5.8 8.6 8.5 14.4 24.4 15.5 26.1 16.4 25.9 33.3 14.4 21.5 20.3 19.8 19.4 7.3 35.0 5.4 25.8 20.8 13.3 25.0 16.0 16.9 32.7 12.2 12.8 25.3 15.1 12.2 30.1 10.9 5.1 22.2 14.0 16.8 16.2 23.2 24.3 16.0 18.0 9.0 23.3 15.3 20.9 20.5 10.2 27.9 17.2 14.8 17.9 10.9 19.1 18.9 12.8 28.7 17.2 3.6 16.8 15.9 22.8 13.6 24.0 20.5 12.6 23.1 18.1 9.9 13.1 14.8 15.4 18.7 29.6 0.7 0.5 0.0 1.0 0.6 1.4 1.2 1.0 1.6 1.0 0.3 1.1 1.4 0.4 1.4 0.6 1.2 0.4 0.7 7.3 10.5 9.7 9.4 6.5 10.1 9.9 9.0 10.3 9.6 8.9 14.4 21.1 16.0 16.3 20.5 6.3 9.8 14.1 11.6 15.9 19.6 16.2 12.1 26.0 11.5 13.0 40.5 4.2 16.7 3.7 8.5 1.9 8.9 2.1 13.7 20.3 19.0 7.3 9.7 13.2 10.0 11.9 20.4 12.2 13.7 3.8 23.1 65.0 27.5 9.6 13.5 18.3 11.5 10.2 14.8 11.9 5.0 17.4 8.3 10.6 25.3 5.5 11.9 9.2 23.6 39.7 13.0 6.4 18.4 7.9 15.6 10.7 10.7 18.8 17.6 6.6 13.4 14.9 11.9 9.8 16.6 12.1 9.2 7.8 32.6 12.0 14.1 INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA057299: AB_2683403" "unprognostic (1.08e-2)" "unprognostic (3.12e-2)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.96e-1)" "unprognostic (4.81e-2)" "prognostic unfavorable (2.54e-6)" "unprognostic (3.07e-2)" "unprognostic (6.87e-2)" "unprognostic (9.77e-3)" "unprognostic (4.84e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.24e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.96e-2)" 8.8 7.5 4.4 13.9 4.8 15.5 8.1 8.3 6.4 14.5 6.9 12.8 7.8 13.2 4.2 10.5 9.5 7.3 10.2 4.8 6.4 6.4 8.9 7.5 17.4 5.7 4.4 11.4 13.5 10.1 8.3 9.4 4.6 10.4 14.8 10.3 11.0 8.7 12.6 10.3 10.6 13.6 4.0 9.9 10.6 30.6 6.3 20.6 8.8 12.0 13.6 10.4 10.4 6.1 52.4 31.9 49.2 43.4 17.7 41.7 25.5 27.5 26.0 35.7 33.0 22.5 38.0 52.3 25.2 20.7 44.3 31.5 61.3 29.2 47.6 58.1 28.8 45.7 19.3 22.1 21.1 24.6 31.7 17.1 13.5 34.7 29.6 40.8 40.1 35.1 44.4 38.9 22.0 34.5 53.7 20.4 28.1 114.9 55.8 42.7 19.7 29.0 30.0 26.6 34.6 18.4 26.8 7.7 24.1 40.3 37.3 31.6 28.1 16.1 18.9 31.1 25.1 22.0 43.0 45.2 21.6 49.4 32.2 2.1 9.6 15.1 4.6 6.8 7.5 13.4 10.8 11.8 9.3 10.4 11.0 6.5 9.3 9.6 6.6 5.5 10.0 4.5 4.4 4.8 8.3 6.4 4.8 6.4 5.7 4.4 4.6 4.0 6.3 6.1 11.0 16.0 8.6 16.6 19.4 5.9 11.6 9.1 9.6 13.7 6.1 4.6 8.3 5.7 11.6 7.3 33.3 10.0 9.7 10.3 3.9 8.3 36.0 15.0 12.1 11.8 18.0 17.7 44.8 13.4 12.9 10.8 8.6 6.1 12.7 15.2 8.9 5.5 9.5 28.6 40.9 11.8 8.2 11.6 6.6 6.4 16.1 14.0 7.2 25.3 21.6 8.0 16.5 33.2 31.2 10.9 14.6 16.1 18.0 8.8 9.5 5.1 19.7 18.9 6.6 10.6 13.1 54.7 32.5 9.0 7.0 8.5 14.2 11.0 11.1 8.1 CCNE2 CYCE2 ENSG00000175305 "Cyclin E2" O96020 8 94879770-94896678 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 33.6;Oligodendrocytes: 34.5;Spermatocytes: 77.7;Spermatogonia: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Karpas-707: 101.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007825, CAB019374" Enhanced NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "CAB007825: AB_598148, CAB019374: " "unprognostic (1.80e-2)" "unprognostic (4.81e-2)" "unprognostic (7.49e-2)" "unprognostic (2.08e-2)" "unprognostic (2.36e-1)" "prognostic favorable (5.87e-4)" "unprognostic (8.37e-4)" "prognostic unfavorable (8.77e-4)" "unprognostic (3.18e-2)" "unprognostic (2.19e-2)" "unprognostic (3.64e-2)" "unprognostic (1.04e-2)" "unprognostic (7.01e-12)" "unprognostic (1.81e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.03e-1)" 2.0 0.6 3.7 6.9 8.3 37.0 2.2 9.0 7.7 1.7 0.3 5.4 3.6 1.8 0.1 4.7 0.6 2.4 1.4 3.2 5.4 0.5 2.3 1.8 10.9 9.9 8.1 1.5 1.8 0.5 0.6 4.3 8.8 1.2 5.7 5.2 1.8 0.2 0.7 5.9 4.3 2.2 7.4 2.3 4.0 14.5 8.0 15.1 1.7 0.7 9.6 2.1 1.5 13.4 47.2 6.2 24.0 15.0 2.9 5.4 16.5 47.3 16.6 29.4 28.9 11.3 20.6 24.5 31.4 20.3 9.1 24.4 19.4 17.5 39.5 17.4 17.5 49.5 26.6 4.2 0.2 20.2 29.0 1.4 1.1 21.4 2.1 6.4 15.5 30.1 21.7 101.5 42.5 14.2 77.8 9.7 8.1 37.4 14.1 54.1 41.7 11.7 8.1 26.4 34.8 14.5 31.8 8.4 5.9 3.0 42.0 21.2 13.0 30.7 20.2 22.9 42.8 19.1 21.1 59.3 24.8 36.1 23.1 0.0 0.2 0.1 0.8 0.2 0.3 0.3 1.1 1.3 0.7 1.0 0.3 0.6 0.6 1.5 0.1 0.0 5.2 0.6 3.7 8.3 9.0 7.7 3.2 5.4 9.9 8.1 8.8 7.4 8.0 13.4 7.5 6.4 1.7 0.7 3.0 4.2 1.6 2.3 6.8 2.9 5.9 8.9 2.5 0.0 1.9 1.8 6.2 7.2 7.2 12.3 0.0 0.2 6.9 1.3 2.7 3.5 0.0 33.6 2.3 0.2 7.8 2.6 4.1 2.9 0.0 2.1 2.5 1.3 4.4 8.4 2.6 4.0 0.0 2.5 1.9 9.0 1.2 4.8 0.0 0.0 0.0 1.0 1.0 1.5 34.5 0.2 2.4 0.4 14.6 1.1 6.3 0.1 1.1 4.7 6.6 2.6 4.3 77.7 26.2 9.5 3.8 1.9 7.5 1.2 3.3 0.8 NDUFAF6 "C8orf38, MGC40214" ENSG00000156170 "NADH:ubiquinone oxidoreductase complex assembly factor 6" Q330K2 8 94895767-95116455 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047148, HPA050545" Approved NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "HPA047148: AB_2679954, HPA050545: AB_2681166" "unprognostic (1.97e-3)" "unprognostic (1.62e-3)" "unprognostic (2.46e-1)" "unprognostic (1.29e-3)" "unprognostic (8.73e-2)" "unprognostic (3.45e-2)" "unprognostic (7.62e-3)" "unprognostic (2.52e-2)" "unprognostic (9.61e-2)" "unprognostic (3.85e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-3)" "unprognostic (9.44e-2)" "unprognostic (1.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.32e-3)" 4.7 3.1 6.9 4.1 7.7 5.5 5.3 8.8 8.1 1.9 5.1 4.4 2.1 3.2 5.7 4.3 4.2 1.9 8.8 6.4 7.8 4.4 10.9 2.6 4.9 6.9 7.6 3.9 3.1 3.5 2.6 3.6 7.3 3.5 5.5 7.4 2.2 3.4 14.6 5.6 3.0 3.2 6.7 3.1 4.3 4.0 7.6 4.7 6.3 13.8 5.2 2.5 1.7 8.9 7.7 4.5 5.4 5.1 3.5 4.3 11.1 8.0 5.0 6.6 4.8 3.6 3.7 14.8 5.3 3.7 2.0 6.3 7.8 5.4 4.9 3.7 15.1 13.7 10.0 6.7 5.4 5.1 6.9 6.5 9.0 3.8 6.1 3.0 3.8 12.1 9.9 8.0 8.0 6.8 13.0 16.5 5.9 10.0 10.6 8.6 4.3 11.3 6.1 7.3 10.1 5.5 4.1 2.5 10.8 6.5 10.1 4.2 4.8 4.7 3.7 3.7 5.8 10.7 8.5 12.4 3.9 13.5 2.7 1.9 1.8 3.0 2.3 1.1 2.9 5.8 3.2 2.2 2.4 5.4 3.1 2.3 0.9 2.9 2.2 2.1 2.9 1.9 6.9 7.7 8.8 8.1 6.4 7.8 6.9 7.6 7.3 6.7 7.6 8.9 23.4 12.8 15.9 35.3 23.6 9.7 10.1 21.5 19.4 22.7 25.7 27.4 32.0 28.6 21.2 12.9 16.7 24.0 14.3 18.5 43.0 15.8 28.5 13.5 9.1 14.8 12.5 23.3 31.8 34.7 30.2 9.4 10.7 9.8 31.8 21.5 12.1 28.3 22.6 25.2 37.0 15.3 24.4 7.3 5.6 8.1 10.5 10.1 14.2 33.7 12.0 25.6 6.2 43.2 58.3 19.3 18.2 13.9 53.1 11.2 23.2 38.2 24.7 23.6 13.1 11.9 21.4 28.4 43.9 17.9 11.9 10.9 13.0 16.5 19.4 9.5 TP53INP1 "DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B" ENSG00000164938 "Tumor protein p53 inducible nuclear protein 1" Q96A56 8 94925972-94949378 "Predicted intracellular proteins" "Apoptosis, Autophagy, Transcription, Transcription regulation" "Activator, Antioxidant" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 101.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 175.6;Plasma cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.6" "Cell line enhanced" "Detected in many" "Karpas-707: 79.7;U-266/70: 85.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005856 Uncertain Supported Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "HPA005856: AB_10600832" "unprognostic (1.39e-2)" "unprognostic (4.47e-3)" "unprognostic (7.17e-2)" "unprognostic (2.70e-1)" "unprognostic (5.31e-2)" "prognostic favorable (1.11e-4)" "unprognostic (5.72e-2)" "unprognostic (1.16e-3)" "unprognostic (1.28e-1)" "unprognostic (7.54e-2)" "unprognostic (5.00e-3)" "unprognostic (1.23e-2)" "unprognostic (1.87e-2)" "unprognostic (9.83e-2)" "unprognostic (3.13e-1)" "unprognostic (1.18e-2)" "prognostic favorable (5.45e-5)" 11.2 10.6 6.4 23.1 7.9 42.1 12.7 6.0 7.6 11.8 9.7 16.5 17.2 12.7 12.6 10.9 14.7 10.9 10.9 5.5 6.5 11.5 101.9 25.3 36.0 8.5 6.8 9.0 60.4 10.1 7.1 14.4 7.0 22.5 20.2 17.6 17.9 9.2 9.2 13.1 35.5 12.2 7.0 40.6 25.6 28.6 8.0 29.3 10.2 8.6 41.1 13.3 8.7 8.8 0.5 2.5 24.1 9.3 29.4 27.6 24.8 5.8 13.5 2.6 6.2 2.2 0.6 5.3 12.4 11.2 2.3 4.2 0.0 9.5 5.8 0.3 3.0 3.4 5.3 14.8 19.7 0.0 16.8 45.4 22.2 6.9 2.8 22.4 39.8 2.6 1.8 79.7 12.4 1.7 4.0 1.5 2.3 0.1 0.7 3.4 1.9 29.4 6.3 26.5 3.3 19.5 3.6 2.0 5.2 38.5 11.8 3.3 27.6 4.8 5.8 0.0 0.9 85.4 18.9 2.3 8.4 0.0 0.0 54.6 3.7 11.7 1.4 3.6 1.3 11.5 4.0 2.7 1.4 9.7 0.8 0.6 16.9 5.2 2.3 1.4 6.6 2.5 6.4 7.9 6.0 7.6 5.5 6.5 8.5 6.8 7.0 7.0 8.0 8.8 18.5 35.3 35.7 10.7 70.0 4.6 3.0 17.9 8.0 5.2 27.4 11.6 13.2 75.8 27.9 11.0 27.1 6.1 10.1 27.5 3.9 9.3 17.3 39.9 18.1 14.2 83.9 6.7 0.9 21.3 1.5 11.4 11.2 35.9 4.5 18.8 29.3 175.6 12.5 1.7 2.9 20.9 20.3 44.2 5.6 43.3 7.2 12.6 16.0 16.9 17.7 5.3 3.1 12.1 11.0 18.0 32.2 10.1 233.2 18.1 21.6 9.6 66.4 19.8 6.6 11.0 12.7 18.9 5.6 10.8 6.5 5.7 17.9 26.8 4.8 8.7 PLEKHF2 "FLJ13187, PHAFIN2, ZFYVE18" ENSG00000175895 "Pleckstrin homology and FYVE domain containing 2" Q9H8W4 8 95133785-95156685 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 102.6;U-698: 109.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024829 Uncertain NA NA "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "HPA024829: AB_10603127" "unprognostic (4.08e-2)" "unprognostic (2.98e-2)" "unprognostic (5.72e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-3)" "unprognostic (9.67e-2)" "unprognostic (4.83e-2)" "unprognostic (1.19e-1)" "unprognostic (2.67e-1)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.94e-2)" "prognostic favorable (1.49e-4)" "unprognostic (2.55e-2)" "unprognostic (1.32e-1)" "unprognostic (3.01e-1)" "unprognostic (4.61e-3)" 12.4 6.1 5.5 21.3 5.5 84.8 21.6 6.1 6.7 9.2 6.9 16.0 12.6 7.4 14.6 15.4 8.9 11.2 8.9 5.2 5.7 22.2 14.7 17.5 53.1 6.3 5.8 7.3 11.8 6.9 3.6 15.1 6.2 9.3 13.9 14.8 11.8 7.4 10.7 19.5 13.7 7.1 6.6 22.6 21.9 12.3 5.4 23.8 9.7 9.3 56.1 12.7 7.5 8.3 27.5 4.5 7.0 4.2 10.0 11.1 37.6 14.9 20.0 12.7 13.6 11.3 29.7 102.6 12.6 10.5 6.6 33.1 10.9 18.1 18.3 19.2 7.4 49.4 10.0 8.8 9.9 9.9 68.7 7.1 25.0 10.0 18.8 14.9 14.1 32.9 32.6 13.0 13.6 16.8 29.0 12.8 4.2 50.1 20.6 11.5 7.1 14.0 10.4 24.2 9.3 5.4 11.3 13.5 27.8 9.7 36.2 16.0 9.0 9.8 6.7 8.6 8.7 17.2 14.9 109.4 7.5 22.8 14.1 107.2 21.6 43.0 9.0 18.6 10.8 69.7 11.2 13.9 24.3 78.6 12.9 12.7 29.8 12.4 16.0 10.1 13.7 19.4 5.5 5.5 6.1 6.7 5.2 5.7 6.3 5.8 6.2 6.6 5.4 8.3 29.3 12.8 14.1 7.2 88.8 61.4 73.4 29.7 56.3 17.0 49.0 22.7 7.0 31.5 26.1 5.5 14.6 51.6 17.8 46.7 29.4 13.6 59.5 47.1 12.0 18.5 33.6 34.5 5.0 22.0 36.1 11.9 31.1 59.5 60.4 14.4 25.0 11.0 29.6 6.7 2.4 14.6 57.0 22.6 54.0 19.8 8.7 34.7 21.4 14.0 31.9 19.1 13.4 10.6 4.7 14.6 39.0 3.8 21.3 42.4 20.7 95.9 26.2 31.7 13.1 10.8 14.5 55.2 16.0 47.2 57.7 50.9 27.4 6.0 17.7 75.4 C8orf37 "BBS21, CORD16, FAP418, FLJ30600, MOT25, RP64" ENSG00000156172 "Chromosome 8 open reading frame 37" Q96NL8 8 95244913-95269201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Cone-rod dystrophy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024198 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Plasma membrane, Cell Junctions" "HPA024198: AB_1845775" "unprognostic (7.90e-2)" "unprognostic (1.98e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.72e-3)" "unprognostic (4.20e-3)" "unprognostic (2.04e-2)" "unprognostic (8.94e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (6.11e-3)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (6.72e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-2)" "unprognostic (3.29e-1)" 1.7 1.8 1.7 1.2 1.9 0.9 2.3 2.3 2.2 2.3 3.2 1.0 0.9 2.4 3.1 1.0 3.9 1.4 2.7 1.7 1.8 2.4 1.8 1.5 2.2 2.3 2.9 4.8 1.2 3.5 2.3 1.8 2.2 2.0 0.9 5.0 1.5 1.7 1.1 1.5 1.0 2.3 2.7 1.7 1.1 1.7 1.8 2.4 2.4 1.8 1.9 1.2 1.4 2.9 2.8 4.5 3.6 1.9 1.2 3.3 1.0 1.2 2.7 1.5 2.0 0.7 6.0 5.6 2.8 2.0 3.8 2.3 1.5 3.1 3.3 1.8 1.4 4.4 2.7 2.0 1.4 0.9 2.3 3.3 1.4 1.8 5.0 3.9 2.3 3.3 2.3 3.2 2.0 2.1 4.8 1.1 1.1 5.6 3.0 2.5 1.9 1.4 3.4 1.2 3.5 3.4 2.5 0.5 2.1 2.7 4.2 0.8 2.0 1.9 2.4 1.6 1.2 2.9 3.0 3.8 3.6 2.1 2.4 0.3 0.3 0.1 0.2 0.2 0.5 0.4 0.3 0.3 0.5 0.8 0.3 0.5 0.4 0.7 0.1 0.2 0.1 0.2 1.7 1.9 2.3 2.2 1.7 1.8 2.3 2.9 2.2 2.7 1.8 2.9 2.4 3.2 2.6 6.8 2.5 0.9 3.7 2.9 4.0 2.7 1.3 2.4 5.3 0.0 3.3 7.3 2.1 2.5 1.8 0.1 7.9 1.8 10.2 3.4 1.3 1.5 0.0 0.4 6.8 2.7 2.9 2.8 1.1 1.0 0.0 1.9 1.1 3.8 1.3 3.3 5.2 0.1 2.0 1.6 1.2 8.7 3.1 0.8 1.8 1.9 1.8 5.3 0.0 8.5 5.7 1.2 0.2 3.0 0.7 1.9 0.1 4.7 7.9 4.1 0.0 2.5 4.2 6.0 3.5 0.9 1.8 0.8 1.1 3.0 0.5 1.8 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 UQCRB "QCR7, QP-C, UQBP, UQCR6" ENSG00000156467 "Ubiquinol-cytochrome c reductase binding protein" P14927 8 96222947-96235546 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1306.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 5409.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043060 Approved NA NA 2200000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 38: Heart - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "HPA043060: AB_10806376" "unprognostic (5.48e-2)" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (9.47e-3)" "unprognostic (2.15e-1)" "unprognostic (8.41e-2)" "unprognostic (2.79e-1)" "unprognostic (9.20e-2)" "unprognostic (3.98e-1)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (3.92e-1)" "prognostic favorable (2.90e-4)" "unprognostic (1.01e-1)" "unprognostic (7.54e-2)" "unprognostic (1.07e-1)" "unprognostic (5.66e-3)" 198.8 242.2 204.1 128.7 208.6 179.4 146.7 213.8 353.3 180.1 217.8 255.3 172.0 147.7 184.8 148.6 151.3 80.1 926.1 199.4 222.2 284.0 223.6 119.8 150.0 211.4 210.0 243.0 185.4 252.5 198.1 97.6 214.9 137.6 155.9 235.7 206.4 100.3 1306.1 107.0 155.6 129.1 217.9 128.9 193.1 67.8 209.8 145.1 121.1 822.2 160.0 176.0 153.5 216.3 338.9 150.1 202.0 126.9 280.8 287.7 129.6 267.9 202.2 147.6 158.0 132.3 157.2 146.2 395.7 218.5 153.0 162.1 187.1 252.1 193.2 221.6 136.6 483.3 312.6 235.6 208.9 269.5 197.0 337.3 217.3 170.1 258.8 469.7 214.5 246.7 258.2 244.2 225.2 206.1 432.6 406.1 117.8 705.2 227.7 190.4 131.0 274.3 290.5 258.5 182.1 181.3 163.0 60.8 434.5 268.5 250.1 440.2 260.0 92.7 144.4 165.8 288.6 211.2 172.2 344.5 153.2 353.9 104.4 134.4 143.7 141.5 123.0 240.0 152.2 211.3 194.1 156.2 162.1 165.5 235.4 224.3 102.5 130.5 290.1 139.4 241.3 224.4 204.1 208.6 213.8 353.3 199.4 222.2 211.4 210.0 214.9 217.9 209.8 216.3 361.3 445.5 566.8 40.8 601.2 302.2 509.6 1261.7 333.5 299.0 330.1 403.9 5409.1 859.3 687.3 332.9 116.7 637.3 578.6 812.3 2484.8 893.3 1127.8 663.6 588.1 474.6 730.7 467.4 42.9 926.7 513.3 508.6 372.6 525.9 587.0 399.0 732.5 1069.1 1143.8 126.2 50.7 1074.2 608.3 1670.2 624.3 290.2 863.9 661.6 820.0 22.5 1280.8 555.2 748.7 19.1 27.9 791.9 949.4 720.7 415.0 378.9 1166.7 2205.9 482.9 436.7 539.0 745.3 650.7 358.2 245.9 444.4 291.1 598.4 675.0 401.5 1078.0 588.9 MTERF3 "CGI-12, FLJ10939, MTERFD1" ENSG00000156469 "Mitochondrial transcription termination factor 3" Q96E29 8 96239398-96261610 "Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007355 Supported Mitochondria,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria Cytosol "HPA007355: " "unprognostic (4.08e-2)" "unprognostic (1.46e-1)" "unprognostic (4.68e-2)" "unprognostic (2.31e-2)" "unprognostic (3.86e-2)" "unprognostic (6.66e-2)" "unprognostic (2.75e-3)" "unprognostic (3.11e-3)" "unprognostic (6.43e-2)" "unprognostic (2.00e-1)" "unprognostic (3.84e-2)" "unprognostic (8.56e-2)" "prognostic unfavorable (5.88e-5)" "unprognostic (8.67e-3)" "unprognostic (8.81e-2)" "unprognostic (2.27e-1)" "unprognostic (1.74e-3)" 15.0 16.3 16.3 15.3 16.9 11.5 17.9 18.6 21.8 14.0 20.9 14.7 12.6 13.5 22.9 11.6 12.7 12.4 27.8 16.1 17.3 18.3 23.1 12.1 18.2 16.4 16.3 12.1 15.5 22.3 12.6 16.7 17.2 13.5 14.4 16.0 12.9 17.2 30.2 17.0 11.5 16.6 15.9 16.0 12.7 11.8 16.6 16.7 11.9 38.2 19.4 16.4 12.0 17.8 41.1 25.9 38.1 30.3 26.4 27.4 17.5 30.8 25.0 43.9 44.2 18.8 29.6 36.5 63.3 18.2 22.5 22.8 39.7 24.1 53.2 35.6 29.3 52.5 20.6 22.8 37.1 17.9 20.7 27.5 35.4 35.6 33.5 22.9 36.5 39.0 45.1 18.7 44.7 26.9 76.6 52.8 19.8 71.6 39.8 45.9 31.2 28.8 32.7 21.8 25.9 20.4 23.0 6.6 33.8 24.5 34.3 25.0 16.3 30.9 20.8 36.0 27.7 21.3 28.9 43.2 33.4 47.3 41.3 39.5 13.4 6.1 15.6 15.9 22.6 20.4 17.7 17.8 20.2 17.7 19.8 20.2 2.2 23.8 15.8 24.3 18.6 10.1 16.3 16.9 18.6 21.8 16.1 17.3 16.4 16.3 17.2 15.9 16.6 17.8 10.4 3.2 6.9 7.8 10.8 0.0 21.2 0.0 10.8 0.0 6.6 8.5 31.2 5.7 5.6 5.5 0.0 30.4 10.8 0.9 13.7 12.5 5.6 6.2 10.1 8.1 0.0 12.4 12.9 9.8 21.0 12.7 4.1 5.4 6.3 11.2 6.1 8.0 16.2 0.0 12.6 3.6 0.0 5.2 0.0 4.1 13.7 7.1 0.0 4.7 16.0 0.0 15.5 7.5 14.2 7.7 3.3 13.9 7.0 22.9 3.3 11.1 5.1 0.0 13.1 10.3 9.9 28.2 21.2 9.1 0.0 17.4 8.8 9.5 5.3 11.7 PTDSS1 "KIAA0024, PSS1, PSSA" ENSG00000156471 "Phosphatidylserine synthase 1" P48651 8 96261902-96336995 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016852 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Endoplasmic reticulum" Nucleoplasm "HPA016852: AB_1855878" "unprognostic (1.44e-1)" "unprognostic (1.71e-1)" "unprognostic (1.08e-1)" "unprognostic (7.89e-3)" "unprognostic (7.48e-2)" "unprognostic (5.68e-3)" "prognostic unfavorable (1.08e-5)" "prognostic unfavorable (9.83e-4)" "unprognostic (2.79e-1)" "unprognostic (1.71e-2)" "unprognostic (2.36e-2)" "unprognostic (1.19e-1)" "unprognostic (2.29e-3)" "unprognostic (4.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.55e-2)" 1.6 2.2 1.6 3.4 2.0 4.9 3.1 1.2 2.6 3.5 0.8 3.4 4.1 2.1 2.8 3.7 2.5 3.1 7.2 1.8 1.0 3.7 4.6 2.6 5.6 0.5 0.6 3.6 2.7 8.0 0.6 4.6 1.3 1.9 2.9 0.9 2.0 3.5 2.9 3.2 3.2 3.6 0.2 2.6 1.4 1.9 2.0 3.6 4.5 3.0 5.2 2.6 1.1 1.4 14.9 11.6 2.0 5.5 4.2 8.5 3.4 10.6 15.5 10.6 7.5 4.6 4.2 24.9 9.5 10.5 2.1 6.0 14.1 11.1 16.1 12.5 10.3 24.5 19.8 2.5 4.3 17.8 8.1 7.2 10.9 14.4 10.2 2.7 7.0 7.6 12.5 12.3 9.7 4.4 14.0 3.0 3.1 5.1 11.1 10.9 10.1 18.8 5.7 12.5 8.6 3.5 3.9 3.4 1.4 2.3 8.2 6.3 11.8 9.1 5.5 6.3 12.3 2.5 13.3 11.8 5.7 19.3 7.5 10.5 2.6 1.5 1.7 1.6 2.5 1.7 2.8 2.2 4.0 2.2 2.5 1.8 0.9 3.2 1.7 1.2 1.7 6.7 1.6 2.0 1.2 2.6 1.8 1.0 0.5 0.6 1.3 0.2 2.0 1.4 12.4 19.2 9.1 8.8 50.5 31.6 18.9 22.6 42.7 10.2 22.9 18.4 94.5 14.3 15.6 11.0 10.4 78.4 23.6 11.9 1.9 20.5 60.1 6.6 9.1 22.9 5.4 38.3 29.3 44.9 54.1 18.0 14.8 9.3 32.4 17.6 34.2 32.1 45.9 5.0 29.2 17.1 10.2 45.3 31.5 52.2 23.3 36.0 19.6 15.9 39.3 4.7 29.9 21.1 8.7 23.9 11.9 25.9 45.5 21.4 16.6 19.0 5.2 4.7 0.0 13.8 15.8 12.1 18.8 33.1 33.5 80.9 34.3 14.6 34.8 16.3 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 TSPYL5 KIAA1750 ENSG00000180543 "TSPY like 5" Q86VY4 8 97273488-97277928 "Predicted intracellular proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.7" "Group enriched" "Detected in many" 8 "Early spermatids: 172.9;Late spermatids: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "JURKAT: 34.9;K-562: 30.5;SCLC-21H: 60.8;SH-SY5Y: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031347 Enhanced Approved "Golgi apparatus,Cytosol" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Golgi apparatus" "HPA031347: AB_10601454" "prognostic favorable (1.21e-4)" "unprognostic (5.13e-2)" "unprognostic (4.90e-2)" "unprognostic (1.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.06e-1)" "unprognostic (1.01e-1)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "unprognostic (3.46e-2)" "unprognostic (1.25e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.40e-5)" "unprognostic (3.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.31e-2)" "unprognostic (3.13e-1)" 6.0 8.6 11.1 4.3 12.6 1.2 12.1 6.7 11.4 11.4 0.8 9.7 1.8 15.2 15.5 4.5 12.4 6.6 12.4 10.0 17.6 10.0 1.7 7.2 6.2 10.3 8.6 25.2 8.7 8.1 11.8 4.3 12.5 15.3 3.2 11.3 9.7 18.3 12.9 4.1 4.1 14.3 7.6 7.3 8.4 44.7 14.4 7.4 8.3 10.5 7.3 9.7 4.6 8.7 0.0 15.9 0.0 0.0 0.4 0.4 0.1 12.4 0.0 12.2 7.9 0.0 0.5 0.0 16.8 14.8 0.0 4.4 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 19.4 0.0 17.2 0.0 0.0 0.2 34.9 30.5 0.0 0.5 23.4 0.0 0.0 0.0 0.0 0.2 23.1 0.0 0.1 10.2 0.1 60.8 47.1 0.0 4.1 0.0 8.2 0.0 1.9 0.0 0.0 26.2 0.1 0.0 14.4 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.5 0.3 0.2 0.1 0.0 0.2 0.0 0.5 0.2 0.0 11.1 12.6 6.7 11.4 10.0 17.6 10.3 8.6 12.5 7.6 14.4 8.7 7.5 6.4 4.1 0.0 5.5 2.3 4.5 0.7 6.8 12.5 9.9 8.8 16.3 2.8 2.1 9.2 20.9 0.2 2.6 0.0 5.9 5.8 172.9 6.4 13.7 9.8 2.4 3.4 0.0 3.5 0.1 12.1 10.2 2.6 0.0 19.2 6.4 0.8 6.3 8.4 0.0 0.3 2.0 5.0 5.9 419.0 24.5 4.6 7.2 0.0 2.2 13.1 0.0 0.0 0.0 3.7 0.0 21.1 0.8 7.8 0.0 1.4 4.1 12.2 6.6 12.4 9.3 35.5 31.0 5.6 1.6 0.1 1.3 9.9 0.3 4.1 MTDH "3D3, AEG-1, LYRIC" ENSG00000147649 Metadherin Q86UE4 8 97644184-97730260 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010932, HPA015104, CAB068204, CAB068205" Supported Enhanced "Endoplasmic reticulum" NA NA 300000 "Cluster 26: Non-specific - Mitochondria" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB068204: AB_2665655, CAB068205: AB_2665654, HPA010932: AB_1079422, HPA015104: AB_1854173" "unprognostic (1.01e-3)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (6.56e-2)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" "unprognostic (4.08e-2)" "prognostic unfavorable (7.76e-4)" "unprognostic (1.25e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (3.84e-3)" "unprognostic (3.88e-2)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" 53.3 41.4 18.6 56.0 26.7 109.9 39.0 26.2 24.5 52.6 27.2 51.3 51.2 50.1 33.7 52.2 41.1 41.2 35.7 17.2 21.2 40.8 89.6 40.7 59.3 28.3 23.2 50.7 30.4 53.4 13.4 28.9 28.6 44.7 47.5 44.8 29.3 41.4 60.2 27.0 52.2 62.5 25.9 41.6 48.1 39.6 23.3 65.9 62.7 50.6 61.0 56.3 22.7 37.1 191.5 96.4 61.1 84.7 97.3 102.7 30.7 167.8 139.0 104.2 79.4 59.9 137.0 173.5 181.5 164.6 114.1 121.6 150.3 115.2 143.6 189.5 79.9 320.0 97.5 69.6 118.2 170.5 142.4 78.6 109.3 128.1 282.2 97.3 119.3 126.2 215.5 300.2 108.4 77.6 286.0 43.2 38.9 160.9 113.0 187.2 73.0 255.4 64.5 108.6 92.3 69.2 118.3 101.3 132.0 58.6 158.0 105.1 126.8 146.7 52.7 135.8 123.6 166.1 196.4 174.5 134.3 194.5 130.9 57.0 71.5 38.1 35.7 49.2 49.7 71.6 51.1 52.8 87.0 51.4 51.9 45.7 10.1 51.4 54.6 112.2 33.3 31.9 18.6 26.7 26.2 24.5 17.2 21.2 28.3 23.2 28.6 25.9 23.3 37.1 185.1 128.2 109.2 69.2 294.6 261.7 233.0 178.9 194.1 0.0 166.1 150.7 109.9 201.6 146.1 141.6 0.0 10.0 231.7 140.5 25.4 230.9 267.4 156.0 269.9 185.1 121.8 205.7 96.4 231.7 98.6 227.2 156.5 178.5 137.1 183.1 164.6 438.0 267.5 0.0 97.0 249.9 146.5 258.7 273.9 163.5 195.4 266.5 184.9 86.2 258.2 0.0 195.7 110.6 141.8 241.8 137.8 216.3 675.9 374.7 160.8 99.2 87.2 0.0 223.5 237.8 334.5 162.1 129.6 249.8 314.8 13.7 200.3 285.6 251.6 315.0 LAPTM4B LC27 ENSG00000104341 "Lysosomal protein transmembrane 4 beta" Q86VI4 8 97775057-97853013 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 380.1" "Cell type enhanced" "Detected in all" "Granulosa cells: 348.5;Rod photoreceptor cells: 575.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;T-cells: 1.4" "Cell line enhanced" "Detected in many" "HEL: 611.7;RPTEC TERT1: 549.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020782, HPA068830" Uncertain Approved "Golgi apparatus" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "CAB020782: , HPA068830: AB_2686044" "prognostic unfavorable (5.63e-4)" "unprognostic (1.91e-2)" "unprognostic (7.04e-2)" "unprognostic (6.83e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (5.70e-4)" "prognostic unfavorable (2.70e-6)" "unprognostic (9.25e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-1)" "unprognostic (7.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-1)" "unprognostic (3.14e-1)" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" 24.2 43.2 30.2 18.0 29.7 5.3 42.9 37.3 29.6 50.1 78.2 34.0 79.7 71.0 29.3 33.7 67.5 46.3 220.9 23.6 35.3 67.3 25.3 39.6 13.7 42.1 36.1 45.1 28.8 185.5 20.3 28.2 39.5 29.2 32.9 380.1 32.8 44.9 153.7 43.9 43.0 47.8 45.2 38.3 32.2 62.5 44.2 8.6 43.0 117.0 20.2 41.0 28.5 50.1 219.2 170.8 171.9 350.3 80.2 61.0 108.1 98.0 50.1 222.9 188.6 103.1 168.0 1.0 378.0 73.5 75.2 241.2 208.8 94.8 242.9 1.5 282.4 611.7 130.6 169.0 66.1 0.3 101.5 83.8 71.0 130.8 66.0 75.1 29.1 69.5 375.7 0.8 92.4 164.1 54.5 34.1 318.8 116.5 106.5 0.6 90.5 0.7 549.4 100.9 172.8 287.1 133.6 63.8 159.4 188.0 154.3 83.7 8.1 47.7 92.0 99.0 70.7 22.4 68.8 2.2 60.8 0.5 144.9 3.3 0.1 0.0 0.5 0.0 1.4 0.3 0.4 0.3 0.1 0.1 0.8 0.9 0.1 0.3 0.0 0.1 0.2 0.2 30.2 29.7 37.3 29.6 23.6 35.3 42.1 36.1 39.5 45.2 44.2 50.1 60.5 102.5 56.1 8.5 4.9 55.2 68.1 63.9 89.4 195.9 59.8 55.6 208.1 82.9 30.9 106.7 223.1 26.6 3.9 17.9 39.2 244.5 7.1 70.6 59.6 77.4 35.4 36.6 15.0 123.6 33.2 72.2 19.4 105.6 12.7 348.5 132.8 32.6 8.6 134.6 36.6 29.6 59.0 3.7 10.1 8.6 23.9 6.6 42.7 4.7 2.8 135.0 1.0 19.1 20.1 72.1 34.4 30.9 1.7 77.0 95.9 62.1 10.5 575.3 59.2 62.6 75.4 7.4 35.8 45.1 44.3 14.1 10.2 119.9 52.1 86.4 MATN2 ENSG00000132561 "Matrilin 2" O00339 8 97868840-98036724 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 201.0;Peritubular cells: 258.8;Theca cells: 297.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 5.2" "Lineage enriched" "Detected in single" 7 "T-cells: 5.2" "Cell line enhanced" "Detected in many" "BJ: 72.5;BJ hTERT+ SV40 Large T+: 78.6;BJ hTERT+ SV40 Large T+ RasG12V: 106.7;HaCaT: 114.4;HBF TERT88: 100.6;SuSa: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033879 Approved "Secreted to extracellular matrix" NA NA 1500000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "CAB033879: AB_2141502" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (2.14e-1)" "unprognostic (4.98e-1)" "unprognostic (5.35e-2)" "unprognostic (7.18e-2)" "unprognostic (5.22e-2)" "unprognostic (2.77e-1)" "unprognostic (2.07e-3)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (6.31e-2)" "prognostic unfavorable (9.65e-4)" "unprognostic (6.65e-2)" 54.4 51.0 24.3 30.2 22.5 1.8 43.6 17.6 23.2 194.4 19.3 67.5 58.5 147.0 101.6 32.8 46.9 40.1 110.2 20.0 23.4 39.3 24.6 15.2 18.0 24.1 30.5 116.4 11.3 28.0 9.9 177.9 26.3 104.9 57.8 45.7 42.6 171.9 4.0 62.8 80.6 98.1 18.3 5.9 23.7 31.2 23.4 4.9 271.4 28.5 15.4 103.0 139.2 30.8 24.1 10.8 23.3 2.5 60.7 3.6 15.0 72.5 17.6 78.6 106.7 13.0 8.4 0.1 7.0 29.2 3.5 114.4 2.3 4.4 100.6 0.0 2.9 0.8 6.1 0.9 14.0 0.0 0.0 13.6 9.5 16.1 0.8 22.1 0.5 1.3 0.1 0.2 4.1 11.2 0.0 0.7 7.1 0.3 3.7 0.0 2.4 11.4 5.7 5.3 16.0 1.5 11.5 0.2 19.8 67.3 10.9 1.4 0.6 5.2 31.5 16.1 11.0 0.9 0.2 0.2 18.8 0.4 5.9 0.0 0.1 0.1 0.2 0.4 5.2 0.0 0.7 0.9 0.8 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.1 24.3 22.5 17.6 23.2 20.0 23.4 24.1 30.5 26.3 18.3 23.4 30.8 27.8 3.2 1.3 11.1 0.3 37.3 10.1 6.2 80.2 6.3 3.8 45.8 29.1 18.6 3.0 16.5 54.2 1.2 0.2 20.6 0.0 9.9 86.0 4.2 22.6 32.4 23.4 3.2 6.4 0.0 1.1 113.1 5.1 5.0 0.0 43.5 201.0 11.0 1.6 0.0 11.5 25.4 0.0 5.0 7.7 108.6 103.5 0.9 28.4 19.7 2.0 8.1 0.0 86.0 59.8 3.2 18.2 258.8 0.0 6.5 118.7 3.4 1.6 52.9 13.1 97.2 17.1 2.5 2.6 7.3 8.5 2.5 2.0 297.5 27.4 1.8 RPL30 L30 ENSG00000156482 "Ribosomal protein L30" P62888 8 98024851-98046469 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002651 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA 310000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 21: OE19 - Mitochondria" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "HPA002651: AB_1079842" "unprognostic (3.28e-2)" "unprognostic (2.19e-1)" "unprognostic (7.36e-2)" "unprognostic (2.42e-2)" "unprognostic (3.48e-3)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (2.00e-1)" "unprognostic (3.34e-1)" "unprognostic (2.89e-1)" "unprognostic (2.49e-2)" "unprognostic (4.76e-2)" "prognostic unfavorable (1.41e-9)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (5.97e-3)" 2169.1 1286.7 1542.9 1403.8 1616.7 3766.6 4078.2 1552.0 2178.4 2624.2 1490.6 1879.4 1171.1 1990.6 2424.1 1907.8 2592.8 1319.4 1503.2 1501.7 1591.6 1375.6 2352.0 1477.3 3296.1 1596.1 1538.2 5616.9 2583.9 1413.7 1079.4 1341.1 1621.2 1773.7 1967.2 634.7 2148.1 1530.1 2778.6 2895.1 1788.4 1618.1 1613.6 1983.8 1841.8 658.7 1566.5 3112.9 1744.0 2442.9 3898.8 2116.9 2144.4 1661.2 3358.5 2302.6 2395.7 2319.1 3463.7 6460.5 2290.5 1929.4 3501.7 3277.9 2880.0 2560.3 3121.6 4403.5 4934.1 2851.4 1408.4 2158.4 3072.1 3675.9 3436.7 1734.7 2547.3 3817.6 2173.7 3445.6 5063.9 2047.0 1830.0 5463.0 5859.2 2408.7 6912.4 3818.6 3479.7 3804.8 2814.6 2850.5 2866.9 4562.1 4848.6 3870.2 2142.9 8254.3 3304.7 2578.5 1815.0 4130.4 2718.3 3174.1 3464.7 2947.9 1117.1 2785.7 4699.0 2414.5 3667.8 4793.0 1873.6 1253.2 1328.9 1885.1 2357.7 2931.8 2681.4 3686.5 1758.0 4203.3 1869.4 1087.1 1542.9 674.9 2014.7 1325.2 2975.8 3533.8 3482.3 2704.0 1937.3 3224.2 4471.8 3686.3 520.5 2037.1 1212.6 1921.8 2476.6 4634.7 1542.9 1616.7 1552.0 2178.4 1501.7 1591.6 1596.1 1538.2 1621.2 1613.6 1566.5 1661.2 3373.1 852.5 1462.3 22.2 6269.8 3791.4 4320.2 2146.2 5538.1 251.5 4342.6 9218.9 66.3 1441.3 1424.1 555.4 139.7 2675.7 4184.6 1233.9 1792.1 1872.1 1333.5 1359.6 3432.8 2196.1 1647.4 2350.9 24.2 3733.5 3914.4 2206.6 1829.8 1820.2 1560.7 3526.6 2224.6 2204.3 2298.9 144.7 28.3 3237.2 642.9 2912.4 4020.1 2532.2 4373.5 3115.9 1988.6 33.7 3957.1 1623.5 3901.2 18.1 54.5 2580.0 2676.0 2403.1 3084.7 4207.4 2142.3 2511.0 640.5 392.2 1406.8 3481.1 2754.6 926.1 635.4 5831.2 4174.6 2901.7 5319.1 2561.6 3407.3 4410.9 ERICH5 "C8orf47, FLJ39553" ENSG00000177459 "Glutamate rich 5" Q6P6B1 8 98064522-98093610 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 34.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 100.1;Ductal cells: 57.6;Endometrial ciliated cells: 27.8;Proximal tubular cells: 24.5;Respiratory ciliated cells: 39.4" "Cancer enhanced" "Detected in many" "liver cancer: 23.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 9 "myeloid DC: 2.2" "Lineage enriched" "Detected in single" 11 "dendritic cells: 2.2" "Cell line enhanced" "Detected in some" "A549: 7.3;HAP1: 8.0;HEK 293: 11.5;JURKAT: 14.7;RPTEC TERT1: 7.5;RT4: 18.2" "Not detected" "Not detected" "HPA025070, HPA025293, HPA027233" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA025070: AB_1845778, HPA025293: AB_1845779, HPA027233: AB_1845780" "unprognostic (2.88e-3)" "unprognostic (1.49e-1)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (6.86e-2)" "unprognostic (2.39e-1)" "unprognostic (8.66e-2)" "unprognostic (1.57e-1)" "unprognostic (4.66e-1)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (5.73e-1)" "prognostic favorable (3.76e-4)" "unprognostic (4.36e-2)" "unprognostic (9.22e-2)" "unprognostic (3.17e-2)" "prognostic favorable (9.38e-4)" 0.5 0.1 1.5 0.3 2.4 0.0 1.0 0.9 1.4 2.5 1.2 1.9 5.3 1.3 0.6 0.7 11.1 12.3 5.3 1.0 2.4 5.6 10.2 0.9 1.0 1.8 2.1 0.9 34.2 2.2 1.3 0.2 1.9 2.7 3.3 2.3 1.3 2.3 0.0 0.7 1.5 0.5 1.1 0.2 12.6 2.4 4.7 0.7 0.6 0.0 0.7 1.9 0.5 1.3 0.0 7.3 0.0 0.0 0.1 0.0 4.7 4.6 1.8 2.3 1.8 0.1 2.4 0.0 6.0 1.2 3.6 0.4 8.0 0.2 2.8 0.0 11.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.3 0.0 14.7 0.0 0.0 0.1 0.2 0.0 0.8 1.6 0.2 2.8 0.0 0.0 0.2 7.5 18.2 4.1 0.2 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 2.4 0.9 1.4 1.0 2.4 1.8 2.1 1.9 1.1 4.7 1.3 0.0 3.2 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.2 2.1 1.3 8.0 100.1 3.1 7.3 0.0 0.3 0.0 1.6 0.0 57.6 0.3 27.8 0.6 0.8 18.0 0.0 1.1 18.4 1.8 0.2 7.7 7.7 0.0 4.3 0.4 2.6 0.1 0.0 1.6 2.4 0.0 0.3 0.0 0.0 0.3 0.7 0.0 0.0 0.1 8.0 0.0 0.5 0.1 14.8 1.6 0.0 0.0 2.5 0.7 24.5 39.4 0.1 0.0 0.2 1.0 0.2 4.7 1.1 0.0 0.1 0.2 0.7 3.6 2.6 RIDA "HRSP12, P14.5, PSP, UK114" ENSG00000132541 "Reactive intermediate imine deaminase A homolog" P52758 8 98102344-98117171 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "kidney: 496.2;liver: 1536.9" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 1579.1" "Group enriched" "Detected in all" 5 "liver cancer: 162.2;renal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 191.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022856, HPA023489" Enhanced NA NA 5000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA022856: AB_1858253, HPA023489: AB_1858252" "unprognostic (1.67e-2)" "unprognostic (3.73e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (4.16e-1)" "unprognostic (2.20e-2)" "prognostic favorable (9.61e-6)" "unprognostic (6.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (4.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (2.04e-1)" "unprognostic (2.08e-2)" "unprognostic (1.51e-2)" 50.1 48.4 93.1 11.4 96.4 7.5 19.1 95.5 131.7 11.2 83.8 24.5 30.5 8.4 22.7 14.3 9.4 22.7 32.3 89.2 95.0 496.2 1536.9 9.5 10.1 91.6 97.8 23.4 27.0 24.6 10.0 10.8 95.5 19.3 24.6 26.6 16.4 11.6 40.0 10.6 21.8 10.8 92.6 7.4 24.8 17.2 100.0 11.2 15.9 41.0 12.3 15.5 7.9 91.0 44.0 37.5 29.3 36.6 65.5 50.4 33.0 39.7 28.0 26.4 31.0 51.4 28.4 62.5 49.6 29.4 34.5 30.8 65.4 56.9 52.5 22.3 28.6 45.0 25.6 55.6 29.9 17.6 7.0 44.4 19.5 36.6 39.9 32.4 34.2 65.3 82.7 12.9 35.5 57.8 35.6 50.1 47.0 191.4 67.8 41.0 21.7 18.4 64.6 31.6 32.2 15.7 25.5 17.4 29.2 37.4 44.5 23.5 20.9 20.6 12.5 33.7 16.3 31.2 46.1 30.9 35.0 39.0 13.2 0.2 9.0 5.6 6.6 7.8 8.7 13.8 9.4 10.1 11.1 11.5 12.0 13.0 1.9 10.3 8.3 8.5 13.9 8.1 93.1 96.4 95.5 131.7 89.2 95.0 91.6 97.8 95.5 92.6 100.0 91.0 7.8 25.6 22.4 0.0 7.4 0.0 0.0 0.0 0.0 0.0 13.8 15.1 0.0 0.0 1.8 47.8 0.0 31.1 3.2 0.0 285.7 19.7 0.0 25.1 12.3 5.0 0.0 0.0 0.0 8.5 29.9 7.9 0.0 9.4 2.5 17.7 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 5.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.8 0.0 0.0 1579.1 5.8 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 14.4 6.3 22.3 0.0 0.0 POP1 ENSG00000104356 "POP1 homolog, ribonuclease P/MRP subunit" Q99575 8 98117293-98159835 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Hydrolase, RNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066194 Supported Nucleoli NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli "HPA066194: AB_2732742" "prognostic unfavorable (2.54e-4)" "unprognostic (9.42e-2)" "unprognostic (5.96e-3)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.26e-6)" "prognostic unfavorable (9.88e-4)" "unprognostic (4.85e-1)" "unprognostic (1.47e-1)" "unprognostic (3.79e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (2.96e-1)" 2.1 1.6 1.7 3.5 1.5 1.5 2.1 3.4 2.3 1.4 1.2 1.9 1.5 1.7 1.4 3.0 1.8 1.3 1.6 1.3 1.2 2.0 1.9 1.6 3.6 1.1 1.4 2.9 1.7 1.7 1.5 1.2 1.1 1.5 4.8 2.4 1.4 1.3 1.7 3.0 1.6 1.8 0.8 2.1 1.9 3.1 1.6 2.6 1.5 1.2 4.4 2.5 1.5 1.8 21.9 12.9 13.8 12.8 4.8 3.3 9.1 18.3 15.2 18.7 13.8 13.4 13.8 15.3 25.6 12.9 9.0 14.3 40.3 18.2 18.9 11.1 17.0 30.0 10.2 9.2 2.1 16.4 18.4 2.8 3.3 20.8 8.2 5.7 14.8 7.2 17.0 13.5 17.7 17.4 23.8 8.3 10.4 25.1 17.6 19.4 7.5 11.0 13.5 11.5 32.8 7.7 8.4 14.2 6.4 7.9 19.2 6.0 18.4 16.3 11.6 20.8 36.5 13.3 13.6 32.7 12.8 17.3 14.6 9.4 5.1 3.9 7.4 5.7 6.0 4.9 5.4 5.0 5.0 8.1 6.8 6.5 0.8 3.8 2.9 6.2 4.9 2.1 1.7 1.5 3.4 2.3 1.3 1.2 1.1 1.4 1.1 0.8 1.6 1.8 2.3 3.2 3.9 10.7 4.7 3.7 8.2 3.8 4.0 7.0 2.5 2.3 3.9 0.0 3.8 5.5 0.0 4.1 4.1 2.7 5.9 8.8 13.8 2.4 6.4 4.2 0.0 5.0 17.7 5.9 3.4 5.8 6.6 2.9 1.3 5.9 1.8 5.4 3.4 1.7 19.0 1.7 2.0 2.4 0.8 3.0 5.3 3.3 0.0 3.7 7.9 2.7 10.3 8.5 11.0 7.8 1.0 4.5 5.2 4.8 1.1 8.5 2.6 9.5 6.6 4.0 6.1 7.7 19.1 9.8 2.4 3.0 4.4 6.1 3.9 5.1 NIPAL2 "FLJ13955, NPAL2" ENSG00000104361 "NIPA like domain containing 2" Q9H841 8 98189826-98294393 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 124.5;Squamous epithelial cells: 57.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 45.5;OE19: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071759 Uncertain NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA071759: AB_2686443" "unprognostic (5.14e-3)" "unprognostic (6.43e-2)" "unprognostic (8.01e-2)" "unprognostic (2.02e-1)" "unprognostic (4.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.72e-1)" "unprognostic (9.45e-2)" "unprognostic (1.90e-2)" "unprognostic (3.67e-1)" "unprognostic (3.42e-1)" "unprognostic (2.41e-1)" "unprognostic (2.18e-3)" "unprognostic (1.28e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-1)" "unprognostic (4.76e-2)" 12.6 12.5 6.1 7.8 6.6 6.4 17.7 4.2 13.5 22.9 5.2 17.8 9.2 14.5 41.0 30.1 12.2 15.4 8.6 7.7 5.1 5.9 7.8 10.3 8.6 3.7 3.5 27.5 16.8 11.7 21.9 8.5 3.8 22.9 24.1 11.7 20.6 15.9 2.3 53.2 11.7 7.8 5.0 8.1 19.7 4.9 4.3 3.4 7.2 2.6 13.0 13.2 21.8 8.8 7.9 3.1 1.0 0.1 45.5 27.5 0.2 13.9 17.6 2.5 3.4 0.0 22.7 14.7 15.7 19.5 3.7 9.2 0.7 8.3 1.9 1.3 2.8 5.4 2.1 1.1 5.8 5.7 5.5 28.4 21.6 2.6 7.6 1.4 3.2 0.1 0.0 29.1 10.2 10.9 0.2 3.1 1.8 38.1 1.1 0.0 0.2 1.7 9.1 17.7 1.5 3.0 10.1 8.6 3.5 1.2 9.2 10.5 9.2 1.9 0.2 7.0 0.1 0.3 0.0 0.1 3.4 18.2 9.5 0.1 2.0 2.9 0.7 1.9 0.0 1.7 0.6 0.6 3.7 2.6 0.0 0.5 0.3 1.7 1.6 1.5 2.0 1.6 6.1 6.6 4.2 13.5 7.7 5.1 3.7 3.5 3.8 5.0 4.3 8.8 6.1 3.2 9.3 3.6 11.0 15.3 8.4 19.2 22.8 16.5 10.4 10.8 5.2 7.2 15.8 3.7 2.1 0.2 3.0 20.6 0.0 8.2 7.3 4.6 21.1 8.0 7.2 11.2 124.5 12.8 1.1 13.2 30.5 5.4 5.7 4.1 8.6 3.6 4.6 21.9 30.5 26.3 6.1 6.8 9.4 4.0 25.7 8.5 3.6 26.2 6.0 9.7 10.3 10.6 3.4 9.4 11.0 23.0 6.6 13.4 8.6 1.2 14.3 2.6 6.6 3.3 6.8 0.8 0.7 57.3 22.9 0.3 3.0 12.4 17.2 22.7 STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98371228-98942827 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 152.7;Oligodendrocytes: 189.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.9;granulocytes: 8.8;monocytes: 8.5" "Cell line enhanced" "Detected in many" "A-431: 85.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007120, CAB025316" Uncertain Approved "Intermediate filaments,Rods & Rings" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: AB_10601664" "unprognostic (7.88e-3)" "unprognostic (1.96e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-4)" "unprognostic (2.95e-1)" "unprognostic (1.12e-3)" "unprognostic (9.68e-3)" "prognostic unfavorable (4.25e-4)" "unprognostic (6.71e-2)" "unprognostic (9.83e-2)" "prognostic unfavorable (9.21e-5)" "unprognostic (9.16e-2)" "unprognostic (1.03e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (9.72e-2)" 15.1 14.4 5.6 7.9 7.0 3.5 14.1 6.6 7.4 17.4 7.2 13.1 5.5 24.9 14.3 10.2 17.0 14.2 9.1 5.1 6.3 15.6 14.3 11.1 5.5 7.7 6.7 25.0 10.0 16.1 6.4 18.5 7.4 16.5 6.7 12.0 10.7 17.6 11.4 9.6 8.3 17.2 6.3 6.8 8.5 11.4 7.1 5.1 11.9 8.6 5.5 13.6 13.7 7.9 85.3 15.7 16.2 22.0 51.2 25.4 16.4 28.8 25.6 26.3 22.8 11.7 35.7 0.0 25.6 28.7 14.1 33.4 11.4 24.8 42.2 20.5 14.8 22.9 7.2 8.0 17.5 7.7 19.0 17.0 41.9 13.5 36.6 17.2 11.5 13.4 9.8 12.2 19.4 10.7 19.3 9.4 4.9 58.0 6.1 17.1 14.1 7.5 29.9 10.7 4.3 9.6 18.4 21.1 18.2 21.0 17.8 12.3 8.7 17.9 11.5 27.1 16.3 9.8 15.5 6.2 15.9 9.5 29.0 2.0 8.3 4.6 1.3 8.5 1.4 1.8 0.7 1.8 7.9 1.1 1.0 0.6 8.8 2.0 5.4 3.3 0.1 2.8 5.6 7.0 6.6 7.4 5.1 6.3 7.7 6.7 7.4 6.3 7.1 7.9 25.9 38.5 37.4 132.9 6.0 43.7 44.8 25.3 23.3 6.9 29.0 15.5 16.6 31.5 37.7 29.5 14.6 43.6 2.5 11.7 23.5 21.5 118.3 23.7 65.8 31.3 9.1 16.2 34.3 18.9 56.1 39.8 9.7 28.9 17.1 13.3 24.3 23.7 19.2 10.1 33.5 7.8 26.4 17.0 25.1 77.1 91.0 18.6 24.9 152.7 13.8 15.0 3.1 60.3 189.9 24.9 13.1 74.1 6.2 42.1 32.3 25.0 29.0 15.6 39.5 43.8 39.7 16.7 12.6 12.3 40.5 64.7 5.9 47.0 13.8 36.0 KCNS2 Kv9.2 ENSG00000156486 "Potassium voltage-gated channel modifier subfamily S member 2" Q9ULS6 8 98426958-98432853 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.7" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.7;Endometrial stromal cells: 3.0;Excitatory neurons: 4.5;Inhibitory neurons: 1.7;Leydig cells: 1.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebral cortex: 4.7;white matter: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 2.1;SCLC-21H: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051417 Uncertain NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "HPA051417: AB_2681478" "unprognostic (7.83e-2)" "unprognostic (9.39e-3)" "unprognostic (5.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.38e-2)" "unprognostic (2.59e-2)" "unprognostic (1.21e-1)" "unprognostic (1.12e-2)" "unprognostic (4.27e-2)" "unprognostic (4.58e-2)" "unprognostic (1.47e-1)" "unprognostic (5.30e-5)" "unprognostic (2.43e-2)" "unprognostic (1.42e-2)" "unprognostic (2.31e-1)" "unprognostic (1.30e-1)" "unprognostic (1.27e-3)" 0.6 0.4 0.0 0.1 0.5 0.0 0.2 0.0 4.7 0.6 0.0 0.3 0.0 0.3 0.5 0.2 0.3 0.4 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.7 0.2 0.1 0.4 1.5 0.0 0.2 0.2 0.7 0.0 1.0 0.0 0.0 0.2 0.1 0.5 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.7 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 4.7 0.6 0.0 0.0 0.0 0.0 0.5 0.0 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 VPS13B "CHS1, COH1" ENSG00000132549 "Vacuolar protein sorting 13 homolog B" Q7Z7G8 8 99013266-99877580 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 160.9;Excitatory neurons: 235.2;Inhibitory neurons: 253.2;Microglial cells: 204.2;Oligodendrocyte precursor cells: 217.1;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043865 Approved "Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA043865: AB_2678704" "unprognostic (4.23e-2)" "unprognostic (1.98e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.65e-3)" "unprognostic (8.60e-2)" "unprognostic (5.95e-2)" "unprognostic (6.52e-2)" "unprognostic (5.19e-2)" "unprognostic (1.59e-1)" "unprognostic (8.93e-3)" "unprognostic (2.90e-1)" 4.0 3.0 2.4 4.4 3.3 13.4 4.7 4.5 3.0 5.4 8.2 3.6 2.3 7.2 3.8 4.4 4.9 4.4 2.3 2.0 1.9 3.8 3.1 3.5 4.8 3.6 2.4 8.1 3.4 6.8 2.3 4.0 3.6 4.9 3.7 6.0 3.2 4.1 2.9 4.0 3.0 5.4 2.2 4.2 3.6 4.9 4.9 7.1 4.7 4.4 5.0 4.5 3.7 5.3 8.6 6.1 7.2 5.3 13.3 15.9 3.6 5.4 9.9 5.3 7.0 3.6 4.3 4.8 6.9 9.3 3.9 3.9 5.0 5.0 9.6 7.7 4.6 10.3 6.5 2.8 4.3 5.0 7.4 10.3 4.6 8.5 12.2 7.4 7.6 7.9 7.9 12.4 6.1 5.3 10.5 2.9 2.3 8.9 2.2 8.3 5.1 9.1 3.5 8.0 2.1 6.0 8.4 4.0 4.0 6.4 7.2 5.6 10.8 7.9 7.4 7.1 4.6 5.0 6.2 12.7 6.0 7.9 5.6 3.0 1.2 2.8 1.2 1.0 1.1 3.3 1.0 0.9 0.5 1.6 1.7 1.1 6.1 0.7 2.3 0.6 1.4 0.5 2.4 3.3 4.5 3.0 2.0 1.9 3.6 2.4 3.6 2.2 4.9 5.3 15.5 19.2 12.2 160.9 24.2 8.8 7.6 9.2 15.4 15.1 8.9 7.6 12.8 10.0 11.9 3.7 37.5 4.9 21.6 7.3 0.0 4.9 8.6 10.9 42.7 11.5 9.0 22.9 235.2 4.6 4.0 18.2 28.1 12.7 3.8 10.4 6.4 5.2 6.5 11.8 253.2 11.9 8.2 15.6 11.3 9.6 27.7 17.8 7.2 204.2 15.0 9.4 17.5 217.1 238.1 4.0 11.0 20.7 19.2 6.2 9.8 2.9 8.2 12.9 0.0 15.7 14.7 23.9 7.3 13.0 9.7 4.2 19.5 14.6 7.4 5.7 COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014295, CAB016244" Enhanced Supported Mitochondria NA NA 210000 "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "CAB016244: AB_2085703, HPA014295: AB_2668966" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (6.90e-2)" "unprognostic (3.37e-2)" "unprognostic (1.58e-2)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-2)" "unprognostic (1.29e-1)" "unprognostic (3.51e-1)" "unprognostic (3.70e-1)" "unprognostic (8.86e-2)" "unprognostic (3.47e-3)" "unprognostic (1.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (6.99e-3)" 134.0 147.5 180.8 52.9 183.9 152.6 125.7 186.1 291.0 166.4 190.2 268.1 334.8 194.0 175.6 197.3 189.5 20.4 781.6 191.8 195.6 254.9 328.5 108.4 71.1 186.0 188.4 161.9 107.3 101.7 159.5 89.9 189.2 162.6 110.4 147.0 108.1 58.1 666.1 121.4 172.3 42.7 182.4 122.9 180.0 170.8 192.7 44.8 129.1 554.1 51.5 188.7 148.6 188.9 137.6 57.8 63.8 251.3 140.0 100.5 103.1 44.5 42.7 30.1 34.3 54.7 284.5 326.8 320.1 70.1 47.7 176.4 36.4 363.3 51.0 60.5 89.1 684.6 66.9 160.4 88.9 319.3 201.9 95.1 475.3 26.0 56.4 129.2 45.1 103.8 49.8 571.1 51.6 134.2 337.9 289.6 117.9 205.5 127.7 381.0 21.2 320.6 453.4 713.3 191.8 115.2 30.9 654.2 351.5 65.0 461.7 201.1 40.1 220.4 286.0 235.8 63.8 140.7 126.3 209.6 310.2 128.2 200.8 345.8 134.7 114.1 177.8 210.5 189.0 209.7 270.6 193.5 212.9 189.8 319.7 294.9 16.6 187.7 266.5 301.9 272.7 252.9 180.8 183.9 186.1 291.0 191.8 195.6 186.0 188.4 189.2 182.4 192.7 188.9 527.8 403.8 485.1 29.7 382.1 490.8 493.5 1431.9 279.4 217.6 561.3 642.7 2146.4 491.8 731.2 605.1 102.2 978.9 416.1 1263.2 2226.5 673.6 834.3 579.3 778.7 436.9 807.5 400.2 27.6 849.4 853.9 502.0 440.4 551.9 362.5 219.3 384.1 1855.5 1066.5 156.5 33.5 1221.3 1027.4 451.1 539.5 266.5 664.8 440.8 732.8 23.4 778.0 545.0 449.0 22.6 32.1 808.6 1338.7 587.5 412.2 448.4 2173.5 1791.0 702.9 282.0 493.0 367.1 555.9 1180.5 505.2 666.4 640.6 1784.9 452.1 428.0 1246.7 715.5 RGS22 "CT145, DKFZP434I092, PRTD-NY2" ENSG00000132554 "Regulator of G protein signaling 22" Q8NE09 8 99960936-100131268 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 61.3" "Group enriched" "Detected in many" 8 "Early spermatids: 619.6;Late spermatids: 1623.3" "Cancer enhanced" "Detected in some" "breast cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RPMI-8226: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA053026 Supported "Nucleoli fibrillar center,Actin filaments,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Actin filaments, Cytosol" "HPA053026: " "unprognostic (3.04e-2)" "unprognostic (2.62e-2)" "unprognostic (4.61e-2)" "unprognostic (3.97e-1)" "unprognostic (3.47e-5)" "unprognostic (1.61e-1)" "unprognostic (2.32e-1)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (1.14e-2)" "unprognostic (1.05e-2)" "unprognostic (7.96e-3)" "unprognostic (1.98e-5)" "unprognostic (3.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.25e-3)" "unprognostic (8.36e-4)" 2.7 0.9 1.7 0.0 2.4 0.0 0.6 1.0 1.5 1.4 10.4 0.3 0.0 2.9 1.1 0.3 10.6 1.2 0.3 1.1 3.9 0.2 0.1 1.7 0.3 5.9 7.4 7.3 0.5 0.0 1.1 0.5 3.7 1.3 0.1 1.0 0.1 2.3 0.1 0.6 0.1 1.5 3.7 0.0 0.1 61.3 5.3 0.1 0.3 0.1 0.3 0.4 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.9 0.6 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.0 0.1 0.0 0.3 1.3 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.0 1.5 1.1 3.9 5.9 7.4 3.7 3.7 5.3 2.9 0.1 0.0 0.0 14.4 0.0 2.2 0.0 1.6 0.6 1.2 1.2 0.8 0.8 0.0 12.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 619.6 58.1 14.2 0.7 0.0 0.0 2.3 0.0 0.2 8.6 0.5 0.8 0.0 1.3 0.0 0.0 0.2 0.0 1.6 0.0 4.1 0.0 2.9 1623.3 131.4 0.4 0.0 6.5 0.0 10.9 0.0 20.1 2.5 0.0 0.0 62.8 0.0 0.0 0.0 0.0 77.2 0.2 0.0 0.4 1.6 70.9 11.1 0.1 2.0 0.8 0.4 8.3 0.0 0.1 FBXO43 Fbx43 ENSG00000156509 "F-box protein 43" Q4G163 8 100133351-100145817 "Predicted intracellular proteins" "Meiosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 3.6" "Cell type enhanced" "Detected in some" "Early spermatids: 11.6;Erythroid cells: 9.9;Late spermatids: 6.9;Spermatocytes: 43.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.6" "Not detected" "Not detected" "HPA024292, HPA024295, HPA024824" Uncertain NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "HPA024292: AB_1848462, HPA024295: AB_1848463, HPA024824: AB_1848464" "unprognostic (4.94e-2)" "unprognostic (4.35e-2)" "unprognostic (2.09e-2)" "unprognostic (4.34e-2)" "unprognostic (5.06e-2)" "unprognostic (3.51e-2)" "unprognostic (1.07e-5)" "unprognostic (4.31e-2)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "unprognostic (4.84e-2)" "unprognostic (1.46e-1)" "unprognostic (0.00e+0)" "unprognostic (7.97e-2)" "unprognostic (2.52e-2)" "unprognostic (5.91e-2)" "unprognostic (8.09e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.7 0.0 0.0 0.0 0.1 0.4 0.3 1.0 0.0 0.1 1.1 0.7 0.1 0.0 0.0 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.5 0.6 0.0 0.3 0.6 0.0 0.9 0.2 0.0 0.1 1.4 0.0 0.0 1.5 1.1 0.0 0.1 0.2 0.0 0.6 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 1.2 0.5 0.6 0.8 1.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.2 1.8 1.6 0.3 0.9 0.6 0.3 0.6 1.4 0.5 0.6 0.4 0.0 3.2 0.0 0.0 0.6 0.4 0.2 0.0 0.0 11.6 1.5 0.4 0.6 1.2 9.9 0.3 0.4 0.3 1.4 0.0 0.3 1.3 6.2 0.0 0.2 0.5 0.0 0.4 0.1 2.0 0.3 1.1 6.9 0.0 0.7 0.0 1.0 0.1 0.6 1.0 0.5 0.5 0.1 0.1 0.4 0.8 0.3 0.2 0.2 1.2 0.8 0.0 1.4 0.5 43.8 4.5 0.7 0.4 0.3 1.6 0.3 0.4 0.2 POLR2K "RPB10alpha, RPB12" ENSG00000147669 "RNA polymerase II, I and III subunit K" P53803 8 100150623-100154003 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA047477 Supported "Nucleoli fibrillar center" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli fibrillar center" "HPA047477: " "unprognostic (3.13e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-3)" "unprognostic (2.75e-2)" "unprognostic (4.68e-2)" "unprognostic (1.58e-2)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (1.57e-2)" "unprognostic (9.75e-3)" "unprognostic (5.73e-2)" "unprognostic (5.65e-2)" "unprognostic (3.46e-2)" "unprognostic (3.07e-2)" "unprognostic (9.16e-2)" "unprognostic (3.43e-2)" 55.2 73.7 65.1 40.9 67.7 66.8 70.4 70.2 110.9 55.3 62.9 51.4 37.7 49.6 71.2 45.0 39.8 41.6 63.8 67.3 72.1 74.5 69.9 48.6 57.9 68.9 67.8 43.4 33.9 80.8 48.4 48.1 69.1 52.1 54.0 61.3 47.5 54.2 45.5 37.3 38.8 47.0 69.0 42.7 47.2 33.2 67.8 64.1 63.3 58.7 58.2 61.4 36.0 70.7 152.7 75.8 95.3 67.3 100.3 91.0 63.9 109.9 90.5 110.1 132.6 46.7 101.5 100.7 214.7 87.8 64.1 67.8 103.4 91.1 144.3 164.8 114.5 138.3 88.8 100.4 79.1 90.3 95.2 74.6 119.0 87.3 88.7 71.1 101.4 116.6 109.7 96.0 108.6 96.5 228.0 132.5 98.9 216.5 148.1 88.7 55.1 146.5 138.4 84.5 199.3 130.1 75.6 65.9 169.9 92.1 134.7 136.0 78.7 64.1 92.3 100.4 119.0 98.1 169.2 160.6 121.8 156.3 102.4 72.5 33.3 50.4 47.8 44.6 58.3 65.6 61.5 60.5 43.1 46.7 54.1 57.9 12.6 58.0 42.5 67.4 70.3 55.7 65.1 67.7 70.2 110.9 67.3 72.1 68.9 67.8 69.1 69.0 67.8 70.7 120.5 67.3 57.8 8.8 101.3 162.6 162.9 263.8 82.6 57.5 115.9 123.3 93.4 82.9 152.2 147.1 16.7 134.7 126.5 75.0 440.3 146.0 6.3 113.1 80.9 101.5 122.1 95.9 18.2 130.1 197.0 105.2 60.1 95.2 109.2 52.1 79.2 122.7 154.1 48.8 17.9 116.9 213.6 72.2 103.9 17.6 117.1 78.6 136.9 8.4 144.3 115.7 122.6 12.1 17.4 141.3 72.0 121.5 127.2 224.7 108.1 388.5 127.8 64.9 72.3 96.8 148.0 139.1 166.6 103.0 170.1 137.6 127.9 92.9 98.8 261.3 SPAG1 "CILD28, CT140, FLJ32920, HSD-3.8, SP75, TPIS" ENSG00000104450 "Sperm associated antigen 1" Q07617 8 100157906-100259278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Fertilization Hydrolase "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 96.0;Endometrial ciliated cells: 190.6;Respiratory ciliated cells: 198.6;Spermatocytes: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023748, HPA053682" Enhanced Supported Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "HPA023748: AB_2671304, HPA053682: AB_2682229" "unprognostic (9.95e-2)" "unprognostic (5.37e-2)" "unprognostic (1.38e-2)" "unprognostic (4.24e-2)" "unprognostic (1.46e-1)" "unprognostic (2.57e-1)" "unprognostic (5.86e-2)" "unprognostic (9.19e-2)" "unprognostic (1.53e-1)" "unprognostic (5.62e-2)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (9.11e-3)" "unprognostic (8.83e-3)" "unprognostic (1.54e-1)" "prognostic favorable (2.62e-4)" 1.8 1.3 3.0 3.6 3.2 10.1 3.0 4.2 3.0 5.4 14.0 12.9 2.9 2.4 1.5 7.8 10.0 3.7 1.5 3.0 4.6 3.2 4.7 5.0 2.7 7.2 9.0 1.0 2.5 9.0 5.7 1.8 6.2 3.1 18.3 1.9 4.6 3.5 0.4 7.9 2.7 1.8 6.0 2.0 6.3 19.4 4.8 2.1 3.4 0.6 4.4 5.3 3.0 5.4 31.3 8.3 0.5 1.8 1.8 1.5 4.6 5.7 3.4 6.8 7.1 8.3 13.5 1.2 20.0 1.8 10.1 16.1 5.9 11.1 6.3 18.1 6.1 5.2 9.0 3.1 2.4 1.4 4.5 1.3 5.8 8.4 6.6 5.3 5.8 5.7 0.2 16.1 1.0 11.2 3.1 1.4 0.5 15.6 9.1 0.5 1.3 4.7 26.1 14.8 4.8 3.5 7.8 6.4 7.0 2.2 9.2 5.9 5.3 6.8 9.8 3.6 14.9 10.9 8.9 0.9 6.5 5.0 3.4 0.0 0.1 0.6 0.1 0.0 0.0 0.8 0.1 0.1 0.1 0.3 0.0 0.1 0.7 1.0 0.2 0.2 0.0 0.0 3.0 3.2 4.2 3.0 3.0 4.6 7.2 9.0 6.2 6.0 4.8 5.4 7.7 48.1 22.8 18.9 7.7 5.6 9.6 18.1 2.2 2.0 13.3 7.7 5.6 22.8 37.2 18.4 0.0 1.3 19.0 32.9 5.9 19.7 96.0 190.6 7.1 6.9 22.1 0.4 30.1 8.6 8.7 5.0 22.4 39.5 10.1 7.3 4.2 8.0 2.8 8.4 21.6 14.9 6.1 2.2 5.3 32.3 5.0 3.9 1.8 6.5 4.5 11.5 5.2 4.5 4.1 14.9 17.7 3.8 15.9 10.3 2.4 10.0 198.6 2.3 0.0 4.8 6.4 91.9 4.7 2.9 5.4 2.3 12.0 1.3 20.1 23.3 RNF19A "DKFZp566B1346, dorfin, RNF19" ENSG00000034677 "Ring finger protein 19A, RBR E3 ubiquitin protein ligase" Q9NV58 8 100257060-100336218 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 178.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011455, HPA023652" Approved NA NA "Cluster 42: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "CAB011455: AB_2180446, HPA023652: AB_1847836" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (1.84e-1)" "unprognostic (7.09e-2)" "unprognostic (3.36e-1)" "unprognostic (2.12e-2)" "unprognostic (7.96e-2)" "unprognostic (8.92e-2)" "unprognostic (1.13e-1)" "unprognostic (5.97e-2)" "unprognostic (5.20e-2)" "unprognostic (2.99e-1)" "prognostic unfavorable (7.99e-5)" "unprognostic (8.44e-2)" "unprognostic (8.19e-2)" "unprognostic (2.02e-1)" "prognostic favorable (3.28e-5)" 32.0 18.8 29.1 32.7 28.7 57.4 28.6 22.7 25.5 52.0 17.6 25.9 24.0 41.3 16.4 21.6 30.5 43.1 25.0 25.3 48.3 30.0 49.3 34.7 55.4 40.2 36.0 27.4 25.9 16.1 15.2 26.9 33.0 22.0 26.5 27.2 22.3 18.7 28.0 31.8 37.9 32.6 37.3 31.5 27.4 53.0 36.1 34.3 18.8 31.0 43.8 35.9 27.3 40.7 26.7 16.9 14.8 16.9 27.7 23.1 18.7 23.4 22.5 22.0 19.9 9.0 17.3 15.7 41.6 24.7 10.2 18.9 11.6 17.4 29.6 65.3 9.4 26.1 86.8 13.5 22.8 5.3 15.6 23.3 26.1 17.5 33.1 26.9 34.3 17.3 14.8 178.6 21.8 13.5 24.6 9.0 5.4 18.2 15.5 9.8 10.0 30.7 60.2 41.7 11.4 24.6 24.5 14.9 23.3 30.6 13.1 20.5 33.9 25.3 19.9 18.7 14.3 85.5 59.3 10.4 16.2 17.4 15.4 26.3 8.6 8.1 16.3 6.8 10.4 15.5 13.4 12.6 5.7 13.9 6.9 9.8 19.6 6.2 14.2 14.1 14.7 5.8 29.1 28.7 22.7 25.5 25.3 48.3 40.2 36.0 33.0 37.3 36.1 40.7 70.8 51.3 51.6 106.7 101.7 40.1 83.4 56.9 18.8 29.9 44.7 32.5 40.6 110.1 83.6 44.1 60.5 11.0 184.8 61.6 7.9 65.0 183.8 165.9 78.2 66.3 20.8 124.8 76.9 40.2 14.5 62.5 67.8 242.1 43.0 172.0 32.2 42.9 23.0 58.9 69.7 25.9 42.7 30.5 41.8 259.4 58.4 39.2 21.4 73.1 24.1 43.5 65.9 35.7 39.9 49.0 32.0 68.8 161.7 66.3 50.9 54.1 106.2 48.4 19.7 77.4 46.3 77.8 47.2 26.1 60.4 8.2 204.6 46.3 21.8 144.9 ANKRD46 ENSG00000186106 "Ankyrin repeat domain 46" Q86W74 8 100509752-100559784 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013758 Approved Approved Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Cytosol "HPA013758: AB_10962626" "unprognostic (3.71e-3)" "unprognostic (9.01e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-2)" "unprognostic (9.82e-2)" "unprognostic (1.16e-1)" "unprognostic (2.63e-1)" "unprognostic (8.84e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (2.98e-2)" "unprognostic (1.51e-1)" "unprognostic (8.08e-3)" "unprognostic (5.29e-2)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (6.29e-3)" 19.2 38.7 29.1 8.4 30.2 2.2 14.6 25.1 33.6 15.1 15.6 9.2 10.2 12.7 16.3 12.7 11.4 7.7 20.1 30.1 25.8 32.7 41.6 10.7 9.9 22.3 22.2 22.6 18.5 16.1 10.3 20.8 24.4 13.5 9.1 35.2 17.1 13.2 62.2 11.2 11.0 12.4 24.9 11.1 11.6 8.3 24.0 15.4 20.0 36.2 10.9 9.5 9.9 28.7 10.0 12.2 17.9 10.1 13.6 8.0 20.0 12.8 5.8 9.6 8.1 17.8 5.9 31.2 23.3 4.4 3.1 7.5 18.5 9.5 10.1 11.2 16.3 39.0 6.4 14.1 7.7 9.3 4.7 5.8 17.1 6.1 10.2 10.3 11.9 21.4 20.8 9.9 9.3 11.4 43.3 16.8 13.1 25.6 9.0 33.1 6.0 21.0 14.1 10.6 19.8 20.1 5.5 9.9 8.5 21.5 14.8 15.7 9.0 4.4 4.9 6.5 5.1 23.0 23.8 25.7 4.8 29.6 7.2 16.4 7.3 7.6 14.4 3.7 17.1 12.7 13.5 12.4 9.6 11.1 17.5 15.2 1.8 16.9 6.8 8.8 13.8 10.9 29.1 30.2 25.1 33.6 30.1 25.8 22.3 22.2 24.4 24.9 24.0 28.7 11.5 6.4 3.9 17.9 14.2 10.8 11.3 9.0 19.4 30.1 10.7 7.4 13.1 12.8 4.8 22.0 18.8 32.1 12.2 5.7 29.4 8.3 1.2 4.6 6.7 12.5 7.3 12.2 41.5 6.0 14.1 11.9 9.7 4.7 4.5 13.8 21.8 34.6 11.4 67.3 36.9 7.6 2.0 6.7 9.3 2.2 21.1 4.0 10.6 24.4 8.1 46.4 10.3 24.1 23.4 3.3 9.1 26.4 13.8 10.5 20.3 61.8 6.5 31.5 26.3 15.1 12.8 14.4 17.2 13.9 14.2 23.4 9.3 11.9 8.5 9.6 SNX31 MGC39715 ENSG00000174226 "Sorting nexin 31" Q8N9S9 8 100572889-100663415 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 6.5;urinary bladder: 16.4" "Cell type enriched" "Detected in some" 4 "Early spermatids: 81.8" "Cancer enriched" "Detected in many" 22 "urothelial cancer: 24.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RT4: 80.7" "Region enriched" "Detected in single" 5 "thalamus: 2.6" "Not detected" "Not detected" "HPA024284, HPA053466" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" Cytosol "HPA024284: AB_1853894, HPA053466: AB_2682161" "unprognostic (1.39e-1)" "unprognostic (3.83e-2)" "unprognostic (7.99e-2)" "unprognostic (1.52e-1)" "unprognostic (7.20e-5)" "unprognostic (1.04e-1)" "unprognostic (1.01e-2)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.79e-3)" "unprognostic (1.66e-1)" "prognostic favorable (1.47e-4)" "unprognostic (2.54e-1)" "unprognostic (4.05e-2)" 0.6 0.1 1.0 0.0 1.2 0.2 0.4 0.8 3.1 0.4 0.6 0.3 0.0 0.3 0.2 6.5 0.3 1.1 1.7 1.0 1.1 0.2 0.5 0.1 0.4 0.0 0.0 0.4 0.3 0.3 0.2 0.0 0.0 1.4 0.1 0.2 1.2 0.2 0.6 0.6 0.1 0.5 0.4 0.1 0.7 4.0 0.7 0.3 0.5 0.5 3.6 16.4 1.7 1.5 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.0 0.0 0.0 80.7 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.6 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.0 1.2 0.8 3.1 1.0 1.1 0.0 0.0 0.0 0.4 0.7 1.5 0.5 0.0 0.0 6.2 0.1 0.4 3.3 0.2 9.6 0.0 0.2 0.6 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 1.9 0.0 81.8 0.2 0.1 0.4 0.0 0.0 12.8 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 19.7 0.6 0.2 0.0 1.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 1.2 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.3 3.7 0.3 0.5 9.7 0.4 0.0 0.1 0.0 0.0 6.0 PABPC1 "PAB1, PABP1, PABPC2, PABPL1" ENSG00000070756 "Poly(A) binding protein cytoplasmic 1" P11940 8 100685816-100722809 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Nonsense-mediated mRNA decay" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011536, HPA045423, HPA067156" Supported Supported Cytosol NA NA 3900000 "Cluster 39: Non-specific - mRNA processing" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Cytosol "CAB011536: AB_777008, HPA045423: AB_2679320, HPA067156: AB_2685793" "unprognostic (5.00e-2)" "unprognostic (2.64e-2)" "unprognostic (3.18e-1)" "unprognostic (4.50e-1)" "prognostic favorable (2.51e-4)" "unprognostic (1.93e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (2.51e-3)" "unprognostic (5.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.21e-3)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.70e-12)" "unprognostic (6.22e-2)" "unprognostic (2.55e-1)" "unprognostic (6.98e-3)" "unprognostic (1.40e-2)" 627.6 341.5 48.8 490.8 73.4 364.0 575.7 54.9 58.6 700.3 86.2 524.3 450.2 453.5 68.3 1353.3 437.0 227.1 233.8 35.3 80.2 296.4 347.7 490.3 542.4 104.1 58.7 724.0 728.0 126.7 167.7 214.5 92.2 473.9 270.3 80.2 1287.6 172.7 197.7 732.4 502.0 226.5 64.1 483.1 524.7 507.9 92.7 421.0 303.4 75.8 532.3 630.5 853.3 81.6 2069.1 644.4 372.2 842.0 585.0 1050.0 793.4 504.4 593.5 451.8 468.7 791.5 1107.8 3230.4 1609.1 809.5 291.3 792.4 554.6 1092.3 459.5 758.2 555.4 1713.1 302.2 562.6 835.7 673.3 891.0 1338.6 1050.2 554.8 2126.1 950.7 690.8 1071.8 1339.4 1120.1 477.5 857.3 2617.8 949.5 882.3 1487.3 929.6 967.5 541.7 1074.2 301.8 953.1 629.2 650.1 415.8 548.6 1200.7 513.2 1031.7 949.5 1005.1 512.4 809.4 723.9 897.9 753.6 606.1 1523.2 609.7 1378.1 538.8 122.8 401.3 131.2 159.3 405.2 348.9 297.4 333.0 264.3 421.4 263.0 437.4 370.4 112.5 306.9 468.5 277.2 301.5 568.0 48.8 73.4 54.9 58.6 35.3 80.2 104.1 58.7 92.2 64.1 92.7 81.6 348.4 371.8 939.1 28.7 1089.1 787.4 1075.3 735.0 1067.7 66.5 1036.1 641.2 139.7 459.0 1020.8 110.3 50.1 454.2 872.8 457.0 264.1 467.0 1727.8 352.1 628.4 523.0 477.1 999.1 42.4 769.0 860.8 458.8 530.1 436.1 1054.1 357.3 570.8 308.3 615.5 72.3 34.1 853.8 360.1 1520.8 1162.9 306.0 498.9 1144.3 370.0 53.4 1583.7 167.7 679.7 29.7 41.1 626.9 698.0 424.3 674.4 655.3 446.1 388.4 473.5 88.4 499.6 530.4 876.7 1433.1 476.0 929.6 765.3 777.9 1041.1 408.3 1061.2 1296.9 YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2118.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005065 Approved NA NA 320000000 "Cluster 38: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "CAB005065: AB_2218378" "unprognostic (4.70e-3)" "unprognostic (7.38e-3)" "unprognostic (8.09e-2)" "prognostic unfavorable (3.91e-4)" "unprognostic (1.83e-3)" "unprognostic (2.00e-2)" "prognostic unfavorable (2.28e-5)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.65e-1)" "unprognostic (3.72e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.03e-6)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" 379.0 262.9 246.2 374.2 324.1 527.2 251.7 147.4 343.0 269.6 88.3 475.2 327.3 275.6 220.9 892.8 243.9 333.0 187.3 366.2 269.6 224.9 190.9 275.8 429.3 163.3 195.7 227.7 191.5 233.3 109.0 339.2 222.5 265.8 445.9 285.3 244.8 291.2 95.0 399.4 375.4 356.5 170.1 272.8 365.4 226.8 276.9 434.8 289.7 168.9 566.1 501.0 343.2 205.0 1902.4 879.2 1605.4 457.7 396.6 490.9 808.0 877.6 1099.2 1124.6 1098.2 602.4 1149.5 816.5 857.1 1349.3 937.2 785.0 1025.5 1213.5 1630.1 765.1 454.2 779.5 579.0 378.1 524.8 311.5 840.3 475.4 1524.0 936.7 1430.1 923.8 1008.7 584.9 887.8 758.9 920.2 660.6 1357.1 535.4 548.0 2269.0 1026.7 569.7 468.6 544.8 1023.1 963.5 889.7 642.7 669.5 609.8 1365.4 1094.7 896.0 374.6 879.0 554.6 834.3 693.7 798.3 503.6 625.3 994.6 925.8 595.2 2303.2 1340.5 427.5 705.8 559.0 589.1 559.3 484.8 463.3 537.3 497.3 395.9 348.3 441.8 616.5 503.7 726.9 313.4 663.9 1087.2 246.2 324.1 147.4 343.0 366.2 269.6 163.3 195.7 222.5 170.1 276.9 205.0 199.4 250.0 228.9 43.1 637.6 1007.0 438.4 309.3 507.6 120.4 285.9 209.9 87.0 188.8 321.3 263.0 89.6 243.4 491.2 552.7 121.3 405.2 1092.9 359.6 245.6 216.0 265.3 137.3 150.2 421.3 551.6 277.4 448.5 578.8 452.9 122.1 183.1 104.5 276.3 134.6 92.5 525.2 244.1 303.5 641.2 2118.0 125.6 456.9 391.3 56.2 334.9 110.9 407.8 51.3 91.5 771.0 452.7 147.1 457.2 427.2 310.6 160.4 292.0 96.3 131.5 229.4 290.4 170.2 92.6 908.0 1184.7 408.9 596.5 116.5 371.7 794.9 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7 GRHL2 "BOM, DFNA28, FLJ13782, TFCP2L3" ENSG00000083307 "Grainyhead like transcription factor 2" Q6ISB3 8 101492439-101669726 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Corneal dystrophy, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.1;Respiratory ciliated cells: 28.8;Squamous epithelial cells: 27.1;Suprabasal keratinocytes: 26.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 39.3;CACO-2: 28.0;HaCaT: 46.3;hTCEpi: 35.5;MCF7: 32.7;OE19: 37.9;RT4: 68.9;T-47d: 79.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004820, HPA062839" Uncertain Supported Nucleoplasm NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA004820: AB_1857928, HPA062839: AB_2684878" "prognostic unfavorable (6.43e-4)" "unprognostic (2.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.68e-1)" "unprognostic (4.79e-2)" "unprognostic (1.90e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (8.59e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (2.61e-2)" "unprognostic (8.29e-4)" "unprognostic (4.54e-3)" "unprognostic (2.64e-1)" "unprognostic (1.08e-1)" "unprognostic (1.03e-2)" 0.1 0.0 0.0 1.0 0.0 0.0 12.3 0.0 0.3 6.9 0.0 8.0 4.0 1.7 16.1 20.4 8.5 3.3 0.0 0.0 0.0 6.3 0.4 5.6 0.0 0.0 0.0 0.0 11.1 9.3 0.8 6.7 0.0 23.2 9.2 0.0 14.8 7.2 0.0 28.6 4.3 0.4 0.0 0.1 9.8 0.3 0.0 2.9 10.2 0.0 4.6 7.7 10.4 0.0 39.3 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 28.0 18.9 0.0 0.0 0.1 0.0 46.3 0.0 22.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.7 0.0 0.3 0.2 37.9 0.0 0.0 0.0 0.1 0.0 68.9 1.9 0.0 0.0 15.0 0.0 4.4 79.7 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 32.1 13.0 0.3 0.0 24.3 10.5 7.6 20.5 0.0 14.4 6.1 0.7 17.2 20.8 11.0 0.0 14.0 0.2 10.3 5.9 7.5 2.4 20.0 1.5 0.8 1.2 0.0 0.8 5.5 7.1 0.8 15.3 20.7 0.0 0.0 0.0 0.0 1.4 0.0 1.3 9.8 2.0 0.0 1.1 9.3 0.0 0.3 1.8 0.0 0.6 0.0 0.0 2.0 0.5 8.8 8.5 0.0 1.3 9.3 5.7 0.1 28.8 0.0 0.0 0.5 1.0 0.1 0.0 27.1 26.0 19.8 0.3 0.1 11.0 6.3 NCALD ENSG00000104490 "Neurocalcin delta" P61601 8 101686542-102124907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 100.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 251.6;Inhibitory neurons: 460.2;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 87.3" "Group enriched" "Detected in many" 13 "NK-cells: 87.3;T-cells: 42.2" "Cell line enhanced" "Detected in many" "AF22: 136.4;HDLM-2: 159.9;U-266/70: 39.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043245 Approved NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA043245: AB_2678385" "unprognostic (3.49e-1)" "unprognostic (1.55e-1)" "unprognostic (4.85e-2)" "unprognostic (4.97e-2)" "unprognostic (5.48e-3)" "unprognostic (2.60e-3)" "unprognostic (1.25e-1)" "unprognostic (5.63e-3)" "unprognostic (1.54e-1)" "unprognostic (2.48e-1)" "prognostic favorable (5.30e-4)" "unprognostic (2.79e-1)" "unprognostic (6.24e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-1)" "unprognostic (7.87e-2)" "unprognostic (1.00e-2)" 21.4 7.3 30.3 9.4 43.4 1.8 44.0 0.0 62.5 13.5 0.0 22.3 6.0 7.6 4.4 12.6 39.6 12.6 12.1 52.4 11.3 14.9 15.1 19.7 13.6 3.6 13.3 37.5 10.0 1.9 13.7 10.0 15.3 12.3 8.8 15.9 100.6 14.9 15.4 18.0 10.2 11.0 1.2 8.3 11.2 7.3 29.4 5.5 5.2 11.6 11.1 11.1 4.0 21.6 6.9 9.8 136.4 0.5 1.1 22.3 0.0 2.3 0.3 0.1 0.0 0.1 0.1 9.0 3.0 10.4 0.6 0.0 1.0 0.0 0.0 159.9 1.0 0.7 0.0 0.0 0.0 6.1 0.9 4.3 0.0 0.3 0.0 0.0 0.0 0.2 0.0 19.3 0.8 0.2 1.2 2.4 1.5 0.0 0.0 3.7 0.0 0.4 22.0 0.3 0.6 13.4 0.0 3.1 5.7 22.5 0.9 4.8 0.2 1.6 0.3 0.2 0.4 39.3 5.6 0.1 0.3 0.1 2.2 0.4 0.3 0.3 42.2 0.2 37.1 0.9 16.0 24.8 5.0 0.6 3.9 20.6 1.3 87.3 0.3 0.4 17.5 13.6 30.3 43.4 0.0 62.5 52.4 11.3 3.6 13.3 15.3 1.2 29.4 21.6 17.3 0.0 2.6 11.8 0.5 4.2 0.5 1.0 0.0 14.6 88.6 74.4 7.5 14.3 3.2 0.0 25.0 3.2 28.9 1.7 7.9 9.6 12.8 32.2 5.0 11.3 21.0 4.0 251.6 1.2 13.0 39.8 4.1 23.8 2.5 20.5 14.6 15.0 1.9 13.5 460.2 4.3 61.1 2.6 6.9 6.6 2.8 2.8 103.2 75.9 0.8 46.6 64.9 281.0 26.5 3.5 0.5 1.5 7.1 1.3 0.0 19.5 26.0 4.7 26.3 91.0 24.5 1.5 1.8 3.0 3.1 3.0 17.4 19.4 0.4 1.1 RRM2B p53R2 ENSG00000048392 "Ribonucleotide reductase regulatory TP53 inducible subunit M2B" Q7LG56 8 102204502-102238961 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, DNA replication" Oxidoreductase "Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006854, HPA028812" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "CAB006854: , HPA028812: AB_10602246" "unprognostic (7.76e-3)" "unprognostic (4.14e-2)" "unprognostic (9.41e-3)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.51e-2)" "unprognostic (1.35e-2)" "unprognostic (1.66e-1)" "unprognostic (9.40e-2)" "unprognostic (1.74e-2)" "unprognostic (1.03e-1)" "unprognostic (1.70e-2)" "unprognostic (4.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.52e-1)" "unprognostic (7.17e-2)" 11.5 21.2 10.5 11.5 12.1 7.1 12.1 13.6 11.5 12.5 26.5 15.3 15.0 11.6 15.1 11.2 13.5 11.9 16.7 10.1 13.7 24.4 22.6 22.0 20.1 13.6 12.4 12.0 13.5 45.0 10.3 13.8 13.9 15.7 15.5 21.9 10.9 13.8 30.4 11.0 10.1 11.7 14.1 14.3 9.5 9.7 12.6 10.1 39.9 34.9 19.6 11.2 5.4 16.8 15.3 26.5 30.7 18.3 43.7 41.3 24.6 34.8 41.4 18.1 21.0 9.6 11.9 97.5 31.8 38.7 18.5 5.7 15.1 35.2 25.3 15.8 16.2 24.4 10.3 20.9 35.3 7.6 50.0 53.1 66.1 20.2 30.5 43.0 51.8 16.3 18.2 14.6 59.1 15.2 13.1 14.6 17.7 16.5 19.2 8.2 12.7 20.1 43.1 17.1 7.8 15.4 17.9 9.7 21.1 76.3 25.5 17.1 39.4 27.8 53.7 19.6 9.6 15.3 15.3 88.0 41.0 11.5 30.2 15.7 6.3 7.0 2.7 5.4 3.8 6.6 2.3 3.2 7.7 8.6 2.6 2.8 23.1 4.1 11.5 2.2 1.8 3.3 10.5 12.1 13.6 11.5 10.1 13.7 13.6 12.4 13.9 14.1 12.6 16.8 16.2 57.7 29.3 10.1 33.5 19.4 8.2 11.8 34.1 13.5 17.0 9.4 22.8 20.0 23.9 40.5 14.6 13.8 13.9 7.3 25.4 6.8 2.3 36.2 11.1 14.9 29.4 3.8 14.6 8.2 5.9 14.8 6.1 11.8 11.4 11.2 18.5 23.6 12.6 10.1 17.6 9.7 10.2 26.2 39.5 1.4 14.3 23.8 17.8 20.6 18.2 24.5 7.2 16.1 12.1 5.7 5.7 14.7 9.3 10.7 8.1 22.7 39.9 18.3 6.6 16.2 16.8 13.2 14.5 26.2 18.5 4.8 12.2 8.6 12.1 6.7 UBR5 "DD5, EDD, EDD1, HYD, KIAA0896" ENSG00000104517 "Ubiquitin protein ligase E3 component n-recognin 5" O95071 8 102252273-102412759 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 239.9;Excitatory neurons: 214.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053688 Supported Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Cytosol "HPA053688: AB_2682230" "unprognostic (3.79e-3)" "unprognostic (7.44e-3)" "unprognostic (1.25e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (2.50e-1)" "unprognostic (1.75e-2)" "unprognostic (7.54e-3)" "unprognostic (8.29e-3)" "unprognostic (3.84e-2)" "unprognostic (6.64e-2)" "unprognostic (3.16e-1)" "unprognostic (1.94e-1)" "unprognostic (1.69e-2)" "unprognostic (2.45e-1)" 33.0 18.3 16.6 22.4 19.4 36.5 30.9 26.5 24.0 25.6 23.4 33.3 14.9 29.6 23.7 27.5 26.1 17.3 25.8 17.3 16.0 17.5 17.7 29.8 33.6 16.0 16.1 32.2 25.7 30.4 24.4 17.8 15.7 20.0 17.0 45.4 26.1 20.7 50.1 35.6 27.2 17.2 13.7 24.2 25.0 43.9 16.6 43.0 21.0 29.6 28.6 28.2 26.4 18.9 64.5 28.4 53.2 27.5 51.8 52.2 48.9 47.4 41.9 36.6 31.7 28.3 42.1 127.1 39.8 44.5 23.7 38.2 46.2 41.1 51.1 55.3 22.7 106.5 39.7 52.2 46.1 33.7 56.3 60.1 40.4 37.5 64.5 41.5 44.6 35.6 52.3 70.2 34.8 58.0 85.3 40.3 40.1 61.8 31.6 49.3 31.6 60.9 33.5 62.3 39.1 32.5 33.4 31.8 34.3 46.1 51.4 35.1 44.6 38.5 44.9 35.1 33.5 37.3 38.7 129.5 38.0 51.2 32.0 1.8 1.5 2.4 2.4 1.5 2.4 2.1 2.5 2.5 1.8 1.7 2.0 3.0 3.0 1.1 2.7 1.6 3.4 1.0 16.6 19.4 26.5 24.0 17.3 16.0 16.0 16.1 15.7 13.7 16.6 18.9 51.4 25.6 31.7 239.9 44.8 52.3 41.2 26.3 55.8 52.0 37.3 29.6 39.8 8.6 49.9 31.3 68.8 27.7 36.2 20.9 9.8 18.8 38.6 47.5 47.0 40.1 33.4 33.2 214.2 15.0 18.9 43.7 37.8 69.0 29.8 64.3 22.9 19.0 17.0 57.2 191.7 19.5 26.4 31.4 52.6 23.6 39.7 43.7 44.4 129.3 43.5 31.3 26.8 196.6 174.0 21.4 18.3 36.5 65.9 45.2 18.3 9.0 46.5 44.8 13.1 66.3 48.4 59.4 30.2 46.8 61.1 69.6 46.9 30.8 19.5 53.5 ODF1 "CT133, HSPB10, ODF27, ODFPG, RT7" ENSG00000155087 "Outer dense fiber of sperm tails 1" Q14990 8 102551589-102561018 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 590 "testis: 397.0" "Group enriched" "Detected in some" 19 "Early spermatids: 208.2;Late spermatids: 322.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA064295 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "HPA064295: AB_2685235" "unprognostic (3.79e-3)" 0.0 0.0 0.4 0.0 0.5 0.0 0.3 0.3 0.6 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.0 397.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.6 0.4 0.4 0.4 0.4 0.4 0.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 208.2 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 322.0 4.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.0 0.0 6.6 0.0 0.0 13.4 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KLF10 "EGRA, TIEG, TIEG1" ENSG00000155090 "Kruppel like factor 10" Q13118 8 102648784-102655725 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 409.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "unprognostic (6.67e-2)" "unprognostic (1.29e-2)" "unprognostic (4.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.42e-3)" "unprognostic (7.76e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.61e-5)" "unprognostic (4.88e-1)" "unprognostic (2.74e-2)" "unprognostic (3.44e-2)" "unprognostic (3.77e-1)" "unprognostic (6.60e-3)" "unprognostic (3.27e-2)" "unprognostic (8.23e-2)" "unprognostic (7.51e-3)" "unprognostic (1.06e-1)" 65.4 28.8 6.1 25.4 7.2 152.8 40.3 4.9 14.3 37.6 8.2 58.4 28.3 40.7 17.0 39.6 42.4 64.9 33.5 7.8 6.8 40.0 95.7 71.3 22.6 6.3 6.8 25.0 126.2 15.2 16.4 71.1 6.0 45.4 46.1 11.4 32.0 33.3 158.9 72.1 26.2 60.3 6.1 34.9 41.1 26.7 6.4 45.6 30.0 122.9 22.3 46.4 27.4 6.2 22.3 32.4 17.3 15.7 30.4 66.3 30.8 43.0 22.9 26.8 12.8 17.3 42.2 35.5 38.2 39.1 49.4 24.0 10.0 106.5 35.4 20.3 17.4 27.6 24.4 15.9 24.7 16.3 41.3 94.5 105.2 36.8 42.1 62.1 60.0 6.8 18.2 68.3 87.2 36.2 17.8 28.3 13.5 58.5 78.8 7.2 59.7 34.0 38.8 67.6 25.4 27.6 64.0 26.3 35.0 25.0 25.4 19.1 67.0 55.9 39.5 65.3 44.0 61.6 51.7 32.6 52.1 20.1 32.2 17.2 52.5 14.3 16.5 48.2 9.0 17.1 12.5 17.2 57.2 5.8 3.1 12.7 5.3 15.6 26.0 10.1 18.4 34.7 6.1 7.2 4.9 14.3 7.8 6.8 6.3 6.8 6.0 6.1 6.4 6.2 195.5 141.1 74.9 1.0 49.2 137.1 167.6 117.3 409.8 3.5 115.9 119.6 117.9 40.0 56.6 44.1 6.2 52.3 41.7 74.6 9.8 58.3 8.5 110.1 121.6 134.7 94.2 11.2 6.7 43.3 87.7 147.7 46.4 183.3 100.1 34.9 94.2 53.5 61.1 8.4 0.6 49.2 93.6 73.1 185.6 10.4 66.5 117.6 76.5 7.5 83.7 7.7 8.2 0.5 0.5 42.7 41.2 29.3 51.4 136.7 35.5 43.8 50.7 2.6 26.3 157.1 124.1 18.7 30.7 222.9 164.8 72.7 47.8 40.6 48.1 58.8 AZIN1 "OAZI, OAZIN, ODC1L" ENSG00000155096 "Antizyme inhibitor 1" O14977 8 102826308-102893864 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027948 Approved Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" Vesicles "HPA027948: AB_10602391" "unprognostic (1.16e-2)" "unprognostic (4.81e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (8.55e-2)" "unprognostic (3.41e-2)" "unprognostic (7.19e-2)" "unprognostic (1.51e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" 61.7 48.1 45.7 48.1 50.3 141.1 57.8 44.8 51.2 55.3 43.5 49.1 66.6 44.4 30.3 52.7 64.0 43.6 51.5 51.9 50.5 39.4 78.0 40.1 58.1 48.1 48.2 38.7 136.6 38.3 31.6 82.8 48.1 52.5 53.6 57.8 47.7 49.5 41.9 32.7 80.8 44.5 53.8 35.9 52.2 35.7 46.7 58.6 67.5 30.9 60.6 62.3 27.3 60.0 320.4 81.7 129.0 92.6 122.7 83.3 77.6 145.4 168.5 103.5 106.8 87.1 217.5 148.0 111.0 121.9 64.3 119.5 113.8 114.5 165.8 244.7 57.4 147.4 30.1 72.3 156.0 81.0 120.7 58.9 136.1 72.5 182.4 92.2 72.8 86.0 112.6 124.0 165.2 92.6 201.8 59.3 144.9 239.3 123.0 87.3 136.5 84.2 108.2 146.7 208.2 327.3 49.1 100.0 144.3 209.9 131.7 84.7 85.9 83.2 83.9 135.7 118.6 122.3 104.2 207.4 98.3 120.1 117.0 73.3 57.7 68.0 31.2 64.1 36.7 43.7 40.8 29.9 55.9 27.5 33.1 32.1 68.5 40.1 64.5 44.3 50.0 65.7 45.7 50.3 44.8 51.2 51.9 50.5 48.1 48.2 48.1 53.8 46.7 60.0 56.3 60.9 27.7 30.0 59.6 93.8 121.1 52.8 93.4 31.5 64.0 39.8 46.3 28.6 52.8 42.3 37.5 148.7 54.0 48.4 52.8 39.6 62.6 95.1 37.9 34.9 84.9 62.7 35.9 50.5 55.0 55.5 59.1 85.4 68.5 31.9 33.5 65.0 54.7 23.5 31.9 77.3 63.1 72.8 127.2 107.9 49.7 86.0 64.0 23.4 53.0 50.4 32.0 30.2 23.7 66.6 44.0 32.4 97.6 106.7 114.6 52.6 167.6 42.3 19.7 36.0 57.1 34.5 30.7 90.8 82.3 261.9 71.6 26.2 66.0 117.0 ATP6V1C1 "ATP6C, ATP6D, VATC, Vma5" ENSG00000155097 "ATPase H+ transporting V1 subunit C1" P21283 8 103021063-103073051 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 162.7;Late spermatids: 166.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023943, HPA057297" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023943: AB_1845197, HPA057297: AB_2683402" "unprognostic (5.73e-3)" "unprognostic (3.30e-1)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (8.82e-4)" "unprognostic (3.29e-2)" "unprognostic (3.87e-1)" "unprognostic (5.62e-2)" "unprognostic (1.19e-1)" "unprognostic (5.59e-2)" "unprognostic (3.98e-2)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (3.88e-1)" "unprognostic (2.83e-1)" 23.8 32.2 31.6 23.8 36.8 9.7 21.6 18.7 38.2 17.8 20.7 15.4 16.1 19.0 14.2 15.6 16.8 19.8 30.1 39.4 28.9 51.7 27.5 18.6 26.2 25.4 24.5 17.7 18.8 39.0 22.2 30.2 31.5 18.3 18.8 36.7 15.3 16.1 17.2 11.9 17.8 20.6 20.2 19.9 17.4 20.9 25.5 21.9 37.8 24.3 24.5 25.2 14.0 26.3 68.4 38.6 20.2 15.6 54.6 39.3 27.7 49.0 49.7 60.6 68.9 30.4 76.7 41.2 58.2 40.8 97.5 29.6 42.4 41.0 87.8 30.3 26.4 39.2 28.0 35.8 59.5 20.8 52.5 28.8 55.4 77.4 36.2 35.6 43.9 28.7 54.6 37.3 71.4 32.1 46.2 16.7 19.1 67.9 37.6 24.6 36.0 36.4 70.3 48.8 28.5 22.6 26.9 26.9 102.0 40.5 58.9 27.8 44.4 33.2 36.1 74.3 35.0 45.1 17.7 42.1 60.2 47.2 33.2 16.8 30.5 38.1 15.1 44.9 17.2 18.7 12.7 15.1 29.0 18.7 14.4 16.0 50.2 18.7 42.7 15.8 23.1 21.1 31.6 36.8 18.7 38.2 39.4 28.9 25.4 24.5 31.5 20.2 25.5 26.3 31.3 32.1 26.4 38.2 22.9 34.9 33.1 31.2 21.1 32.3 21.9 20.6 43.3 15.7 26.5 31.3 16.7 35.4 15.5 14.7 64.6 36.9 162.7 18.3 19.5 25.5 15.6 33.6 64.9 31.5 35.6 28.4 12.2 16.4 24.1 14.0 17.5 19.0 101.8 37.0 56.6 12.4 46.8 47.6 99.6 166.9 24.2 62.8 19.6 36.5 34.3 34.5 14.4 39.2 44.7 30.4 18.2 18.4 25.1 34.7 19.2 139.1 41.2 25.3 19.7 20.7 45.5 11.1 23.4 19.5 32.8 74.8 18.5 17.4 13.5 27.4 BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 300.9;choroid plexus: 108.2" "Cell type enhanced" "Detected in many" "Adipocytes: 67.8;Astrocytes: 198.2;Excitatory neurons: 131.4;Inhibitory neurons: 62.3;Muller glia cells: 132.4;Oligodendrocyte precursor cells: 125.7" "Cancer enriched" "Detected in many" 8 "glioma: 139.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Cell line enhanced" "Detected in many" "AF22: 51.7;BJ hTERT+: 18.1;SCLC-21H: 27.9;SH-SY5Y: 20.5;U-87 MG: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 48: NK-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Nucleoplasm "HPA027132: AB_10600985, HPA068307: AB_2685971" "unprognostic (1.68e-1)" "unprognostic (9.17e-3)" "unprognostic (1.40e-2)" "unprognostic (4.62e-4)" "unprognostic (1.75e-2)" "unprognostic (2.84e-2)" "unprognostic (1.39e-1)" "unprognostic (7.87e-2)" "unprognostic (2.00e-1)" "unprognostic (4.99e-2)" "unprognostic (4.17e-2)" "unprognostic (2.18e-2)" "unprognostic (7.58e-2)" "unprognostic (2.51e-3)" "unprognostic (2.76e-2)" "unprognostic (1.70e-1)" "unprognostic (9.27e-3)" 9.3 15.6 196.7 2.1 209.2 3.4 7.0 182.2 226.6 1.6 108.2 3.1 0.9 1.7 0.4 0.7 3.8 1.6 3.1 201.1 206.8 4.3 2.9 7.3 1.4 240.0 237.4 3.3 2.1 0.4 25.9 5.3 219.5 1.1 1.6 19.4 1.0 0.9 2.0 2.0 2.7 1.8 229.2 14.5 2.4 1.3 300.9 0.6 4.5 1.4 0.8 2.5 1.4 205.3 0.5 3.0 51.7 0.5 0.5 14.9 0.0 2.6 18.1 0.1 0.2 0.5 0.1 0.2 0.5 10.1 0.2 0.8 0.9 0.1 0.1 0.1 3.1 0.5 0.8 0.1 1.2 0.0 1.1 3.0 2.9 0.6 0.0 2.7 0.4 0.1 0.0 0.4 0.1 0.4 0.0 0.2 1.3 0.4 1.0 0.2 0.3 1.2 0.0 0.1 27.9 20.5 0.6 0.0 0.1 4.5 0.2 0.3 3.0 16.0 1.0 0.4 1.0 0.0 0.2 0.2 75.7 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.2 196.7 209.2 182.2 226.6 201.1 206.8 240.0 237.4 219.5 229.2 300.9 205.3 67.8 0.0 1.8 198.2 0.3 5.5 0.7 4.5 0.6 2.1 2.0 1.1 0.8 17.2 5.9 0.0 0.0 0.1 2.1 0.3 7.9 32.0 2.9 15.6 2.3 33.4 17.8 6.1 131.4 25.6 0.1 1.6 0.0 34.0 0.0 0.0 23.6 0.8 0.9 0.0 62.3 3.4 22.4 1.3 6.2 8.7 1.5 2.1 14.2 18.7 4.6 132.4 2.1 125.7 46.1 4.1 1.2 0.0 0.8 0.8 0.1 0.1 21.7 3.3 0.0 2.1 8.1 0.1 0.1 0.3 4.0 0.0 1.3 0.3 0.1 1.1 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 CTHRC1 ENSG00000164932 "Collagen triple helix repeat containing 1" Q96CG8 8 103371538-103382989 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 69.1;gallbladder: 87.8;placenta: 90.1;urinary bladder: 84.6" "Cell type enhanced" "Detected in many" "Endothelial cells: 95.2;Fibroblasts: 181.6;Langerhans cells: 45.9;Melanocytes: 49.8;Smooth muscle cells: 77.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 294.6;fHDF/TERT166: 138.1;HHSteC: 197.1;HSkMC: 406.6;WM-115: 386.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059806, HPA061896" Approved Approved Nucleoplasm "Secreted in other tissues" NA NA 420000 "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "HPA059806: AB_2684130, HPA061896: AB_2684633" "unprognostic (2.04e-2)" "unprognostic (4.58e-1)" "unprognostic (2.76e-2)" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "prognostic unfavorable (1.67e-4)" "unprognostic (4.17e-2)" "unprognostic (3.64e-2)" "unprognostic (8.63e-2)" "unprognostic (1.12e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.22e-14)" "unprognostic (2.33e-3)" "unprognostic (3.21e-2)" "unprognostic (7.96e-3)" "unprognostic (2.37e-3)" 69.1 2.8 1.6 15.4 1.8 0.5 39.0 5.7 6.3 12.8 0.4 6.6 6.3 18.7 3.3 9.7 5.3 87.8 8.9 1.5 2.3 2.3 0.8 8.9 13.8 2.0 1.6 4.2 3.7 2.2 3.7 90.1 2.5 4.7 6.2 2.4 17.0 5.6 3.6 32.5 3.5 19.7 1.8 2.6 3.6 3.6 1.5 6.2 9.1 4.1 16.0 84.6 6.6 3.3 12.1 0.9 3.3 0.8 90.6 294.6 0.2 34.8 9.3 3.7 5.0 1.1 8.3 1.5 36.6 138.1 0.2 0.4 0.1 0.2 17.7 0.5 0.0 0.5 0.6 19.2 197.1 0.9 0.7 406.6 0.5 30.7 0.4 1.4 60.2 2.3 0.5 91.6 18.7 1.7 17.2 41.1 11.0 0.4 58.0 35.8 30.9 1.1 2.9 0.2 5.7 4.3 0.1 0.2 110.8 12.6 0.1 0.2 49.0 4.6 1.8 4.8 0.4 3.0 0.8 0.6 2.2 0.2 386.9 0.0 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.2 0.0 0.1 1.6 1.8 5.7 6.3 1.5 2.3 2.0 1.6 2.5 1.8 1.5 3.3 36.9 3.2 2.3 1.0 6.7 32.0 0.2 12.1 0.0 0.3 0.9 1.4 0.8 1.5 3.6 3.7 0.0 5.6 0.9 0.0 0.0 4.1 0.5 6.4 9.8 95.2 1.2 0.8 2.3 0.6 11.3 181.6 0.0 11.5 0.0 0.5 17.5 0.1 8.0 0.0 2.0 0.0 4.1 0.3 45.9 0.8 12.5 0.9 49.8 3.7 0.6 5.5 1.0 4.5 1.8 1.8 0.0 0.4 24.2 0.8 0.0 0.5 0.8 1.2 0.0 4.7 77.4 4.3 16.5 0.3 27.3 16.6 3.5 1.2 0.2 0.5 SLC25A32 MFTC ENSG00000164933 "Solute carrier family 25 member 32" Q9H2D1 8 103398635-103415189 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024763, HPA047402" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Mitochondria Nucleoplasm "HPA024763: , HPA047402: AB_2680032" "unprognostic (2.45e-3)" "unprognostic (8.19e-2)" "unprognostic (3.87e-3)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.06e-2)" "unprognostic (6.50e-3)" "unprognostic (1.22e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (9.47e-2)" "unprognostic (8.43e-2)" "unprognostic (2.08e-1)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (7.82e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-1)" "unprognostic (4.49e-2)" 13.5 7.2 3.1 12.5 3.9 14.6 11.2 4.1 4.8 8.6 2.9 7.7 6.8 10.7 7.5 7.3 9.3 11.5 9.7 4.1 4.5 9.6 17.9 8.5 16.9 4.7 4.6 9.6 8.5 8.8 11.3 10.1 4.6 8.0 7.7 1.4 6.4 7.5 9.6 6.9 7.6 10.9 4.6 12.7 7.0 6.4 4.0 8.7 7.1 9.2 12.8 15.0 7.0 5.3 33.7 11.5 10.5 18.3 21.3 23.3 10.3 27.4 39.9 30.6 31.4 14.0 19.6 73.8 25.8 29.5 17.7 20.4 22.5 22.5 47.0 45.5 16.1 53.5 8.5 18.3 37.4 26.5 23.1 23.1 17.9 34.5 51.2 8.6 32.5 19.4 33.9 25.9 30.5 13.5 45.0 21.6 17.1 39.3 23.6 33.6 16.3 50.8 20.8 12.7 28.0 17.2 13.6 22.3 48.9 10.5 19.3 18.5 22.6 36.7 24.9 44.2 36.2 19.2 19.7 76.8 31.0 38.1 27.5 0.6 3.3 1.6 6.0 3.7 7.3 7.0 6.4 6.9 4.1 4.8 6.5 6.7 0.8 5.2 4.3 3.5 5.5 5.7 3.1 3.9 4.1 4.8 4.1 4.5 4.7 4.6 4.6 4.6 4.0 5.3 28.9 3.2 3.3 10.1 46.9 23.1 16.7 6.9 32.5 9.4 10.3 6.7 10.4 11.5 5.4 5.5 6.2 11.9 20.9 4.1 7.9 9.8 4.8 8.3 14.0 22.2 11.4 16.2 30.3 9.4 13.6 19.6 27.0 9.1 8.9 8.0 20.0 15.2 10.2 8.4 25.8 7.1 8.2 7.3 11.6 4.7 9.3 16.2 10.6 24.4 9.9 7.6 15.5 25.6 46.6 10.0 3.1 8.6 56.3 14.4 4.1 9.5 2.6 8.1 19.7 13.5 14.7 22.9 17.1 32.6 25.9 14.0 27.7 9.5 7.5 15.1 AC012213.5 ENSG00000285982 "Novel protein" 8 103398658-103501895 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.8;SCLC-21H: 17.6" HPA024763 Approved Nucleoplasm,Mitochondria NA NA "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" Mitochondria Nucleoplasm "HPA024763: " 0.3 2.7 2.1 1.3 2.3 2.7 0.6 4.8 2.6 0.9 0.9 0.7 0.7 1.0 0.8 1.2 0.8 1.3 0.8 1.9 2.9 0.5 0.6 0.6 1.2 2.3 2.1 0.9 0.9 0.6 1.1 2.5 1.6 1.6 6.8 1.1 0.7 0.4 2.0 1.3 1.5 0.8 0.6 1.5 4.9 2.2 0.2 2.9 0.1 1.3 0.9 2.0 0.2 0.8 5.8 0.6 0.0 0.7 0.4 0.2 0.2 0.5 0.9 0.6 0.6 0.0 0.2 1.0 1.1 0.8 0.7 1.7 0.5 0.2 0.2 0.6 1.3 0.2 0.0 0.6 0.4 1.6 1.4 0.2 0.9 3.9 0.3 1.3 0.3 2.2 0.2 0.2 1.2 0.3 2.5 0.6 0.2 0.2 0.8 0.2 0.8 2.9 17.6 2.6 0.0 0.4 0.6 2.4 0.5 0.1 0.4 1.2 0.4 0.1 0.5 0.6 0.6 0.3 0.8 1.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.3 4.8 2.6 1.9 2.9 2.3 2.1 2.5 0.8 2.2 2.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: AB_2678963" "prognostic unfavorable (4.06e-4)" "unprognostic (4.39e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-3)" "unprognostic (3.57e-2)" "unprognostic (7.86e-3)" "prognostic unfavorable (8.05e-6)" "unprognostic (5.92e-3)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.54e-3)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (8.63e-2)" 16.7 19.2 10.3 22.9 11.0 15.2 23.9 11.3 15.6 17.7 12.8 20.7 16.1 16.2 19.1 21.3 18.0 12.7 16.2 10.9 11.1 32.4 20.7 12.9 24.7 10.8 13.7 13.6 18.5 20.0 15.6 18.7 11.4 14.7 21.4 13.8 14.3 12.8 18.8 15.7 14.5 18.2 11.3 14.3 15.6 32.2 10.4 24.7 18.1 16.0 30.5 33.6 14.6 11.9 96.5 84.2 76.9 79.0 54.7 62.7 57.6 70.1 53.2 64.4 65.9 83.1 90.9 132.2 116.1 73.3 64.0 69.9 105.8 89.0 124.1 127.7 74.9 183.0 48.0 95.9 62.2 76.1 75.7 51.8 59.9 95.9 157.5 40.3 91.4 89.6 125.3 56.7 99.9 78.0 144.9 79.3 118.0 268.9 129.6 92.6 93.3 136.4 95.3 78.6 97.6 92.3 43.5 67.3 83.1 67.4 103.9 51.2 60.6 65.3 105.3 85.5 94.7 61.7 116.5 188.0 88.0 162.8 85.7 19.6 37.6 22.1 35.5 46.5 48.8 60.8 37.5 38.2 54.4 50.8 37.0 38.2 4.2 52.8 35.2 28.3 58.0 44.9 10.3 11.0 11.3 15.6 10.9 11.1 10.8 13.7 11.4 11.3 10.4 11.9 40.0 16.0 17.0 9.1 39.7 79.5 76.6 92.4 38.1 19.6 21.6 24.9 20.8 12.8 53.8 33.1 25.0 57.9 34.8 11.0 39.2 55.0 54.6 26.9 35.4 39.9 14.5 22.1 9.5 48.4 75.0 37.4 17.9 24.7 40.6 49.3 17.5 16.9 42.7 16.8 9.0 17.5 69.2 14.8 23.9 16.7 24.2 22.9 26.6 11.2 28.5 28.8 27.8 16.1 20.0 43.6 12.3 17.7 30.3 51.1 24.3 79.1 36.0 23.7 13.1 50.2 48.0 102.0 86.3 37.1 77.0 33.9 33.1 41.7 28.1 56.9 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 DPYS DHPase ENSG00000147647 Dihydropyrimidinase Q14117 8 104330324-104467055 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "kidney: 199.6;liver: 477.6" "Group enriched" "Detected in some" 12 "Hepatocytes: 459.5;Proximal tubular cells: 518.8" "Cancer enriched" "Detected in some" 5 "liver cancer: 57.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024785, HPA070814" Enhanced NA NA 820000 "Cluster 85: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA024785: AB_1847856, HPA070814: " "unprognostic (1.54e-3)" "unprognostic (2.33e-1)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (2.69e-1)" "unprognostic (2.38e-3)" "unprognostic (4.16e-4)" "unprognostic (1.56e-1)" "unprognostic (3.53e-2)" "unprognostic (3.85e-3)" "unprognostic (2.43e-1)" "unprognostic (4.81e-2)" "unprognostic (9.56e-3)" "unprognostic (2.72e-1)" "unprognostic (2.02e-1)" "unprognostic (1.86e-1)" 8.6 2.8 0.6 0.1 0.6 0.0 0.4 0.2 1.7 1.2 0.2 0.2 0.0 0.1 0.6 0.1 0.7 6.5 0.1 0.6 0.5 199.6 477.6 0.6 0.3 0.5 0.7 0.2 0.1 0.6 0.2 0.6 0.6 4.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.3 0.1 0.9 1.2 5.1 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.2 1.7 0.6 0.5 0.5 0.7 0.6 0.3 1.2 0.5 0.1 0.0 0.0 1.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 40.0 0.0 20.2 0.0 0.0 0.0 0.0 27.4 0.1 12.8 0.3 0.1 1.0 0.0 16.0 11.2 0.0 0.0 1.8 0.0 0.3 0.0 0.4 11.7 459.5 1.4 0.0 4.6 0.0 0.0 11.1 0.3 13.5 0.9 10.6 0.0 14.0 0.4 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 518.8 0.0 0.1 0.0 0.0 0.0 1.2 1.7 0.0 0.0 0.0 2.7 0.0 0.0 0.0 DCSTAMP "DC-STAMP, FIND, TM7SF4" ENSG00000164935 "Dendrocyte expressed seven transmembrane protein" Q9H295 8 104339087-104356689 "Predicted membrane proteins, Transporters" "Differentiation, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 4.5;epididymis: 2.0;lung: 3.8" "Group enriched" "Detected in some" 5 "Hofbauer cells: 7.1;Macrophages: 6.5" "Cancer enriched" "Detected in some" 46 "thyroid cancer: 45.3" "Group enriched" "Detected in some" 4 "amygdala: 4.5;basal ganglia: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "unprognostic (1.11e-2)" "unprognostic (1.22e-2)" "unprognostic (8.41e-2)" "unprognostic (2.96e-2)" "unprognostic (8.48e-4)" "unprognostic (2.14e-1)" "unprognostic (5.40e-2)" "unprognostic (1.51e-2)" "unprognostic (3.08e-2)" "unprognostic (1.18e-2)" "unprognostic (5.26e-2)" "unprognostic (2.45e-1)" "unprognostic (1.61e-3)" "unprognostic (8.84e-2)" "unprognostic (1.36e-1)" "unprognostic (8.05e-2)" "unprognostic (8.34e-3)" 0.8 0.0 4.5 0.1 2.6 0.2 0.3 0.0 0.8 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.4 3.8 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.5 2.6 0.0 0.8 0.8 0.1 0.0 0.1 0.1 0.0 0.8 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.7;Excitatory neurons: 78.7;Inhibitory neurons: 53.7;Oligodendrocyte precursor cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.0" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" 5.7 4.7 5.1 3.9 8.8 2.2 4.3 4.7 9.4 6.4 3.1 4.8 3.1 16.5 4.0 4.1 5.8 7.5 13.6 13.8 5.3 6.5 1.5 4.6 1.6 1.8 2.3 6.1 4.5 10.0 3.1 5.3 1.1 6.5 4.8 6.1 3.8 5.9 9.3 3.1 3.0 18.5 2.4 3.7 2.8 4.9 3.1 12.9 6.8 17.2 2.3 7.6 3.2 3.9 18.5 10.6 21.1 37.1 23.4 18.4 4.7 51.5 51.3 17.6 24.6 2.4 17.7 0.0 20.2 49.0 21.2 8.1 8.6 22.0 37.7 34.3 8.2 28.7 4.7 0.8 14.4 0.4 22.1 24.8 15.4 29.5 23.7 63.4 9.1 21.9 6.2 0.0 63.9 3.0 26.5 0.6 5.3 1.6 18.2 2.1 20.5 4.0 13.9 0.8 27.0 16.4 16.4 0.7 44.6 15.8 5.0 5.6 25.7 48.1 31.0 15.7 33.6 23.8 20.2 0.2 25.9 0.0 53.9 47.0 0.3 5.8 0.2 0.8 1.4 0.0 1.0 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.5 0.4 0.1 0.4 5.1 8.8 4.7 9.4 13.8 5.3 1.8 2.3 1.1 2.4 3.1 3.9 4.4 16.0 2.2 42.7 0.2 11.5 6.3 12.3 10.8 17.5 3.9 4.3 11.7 7.2 5.2 14.7 6.2 0.2 1.7 2.0 0.0 4.6 4.3 4.4 16.4 5.9 14.4 2.5 78.7 4.5 0.5 12.6 1.5 5.5 8.2 10.9 4.2 0.8 5.3 28.6 53.7 2.5 10.2 7.9 14.3 2.7 8.7 8.2 7.2 9.4 6.1 3.1 1.0 64.3 25.2 5.1 0.3 9.1 0.1 7.7 1.5 3.8 5.3 8.3 6.6 8.2 11.3 8.5 12.0 3.2 10.9 0.3 3.9 4.5 2.3 5.2 ZFPM2 "FOG2, hFOG-2, ZC2HC11B, ZNF89B" ENSG00000169946 "Zinc finger protein, FOG family member 2" Q8WW38 8 104590733-105804539 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Gonadal differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.2;ovary: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 115.2;Excitatory neurons: 524.4;Inhibitory neurons: 159.8;Microglial cells: 152.7;Oligodendrocyte precursor cells: 689.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 64.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.4;BJ hTERT+: 14.2;HHSteC: 9.9;hTEC/SVTERT24-B: 5.7;HUVEC TERT2: 10.9;K-562: 6.0;TIME: 6.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 39.4" HPA004094 Approved Supported Nucleoplasm NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA004094: AB_1859058" "unprognostic (4.48e-2)" "unprognostic (3.24e-2)" "unprognostic (7.77e-3)" "unprognostic (1.36e-2)" "unprognostic (3.51e-1)" "unprognostic (1.53e-1)" "unprognostic (8.37e-2)" "unprognostic (8.35e-3)" "unprognostic (1.97e-2)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-6)" "unprognostic (4.10e-3)" "unprognostic (5.41e-2)" "unprognostic (1.63e-4)" "unprognostic (2.61e-2)" 12.2 2.8 7.4 1.5 3.1 0.0 4.5 64.2 12.7 6.5 0.0 4.3 0.5 10.7 2.3 4.5 12.3 5.8 10.2 16.4 3.5 1.1 2.7 3.8 2.7 11.9 5.7 33.3 0.7 0.4 1.1 4.2 12.3 0.9 2.1 1.1 1.0 1.9 18.0 1.6 1.9 17.8 0.2 2.9 2.8 4.3 6.3 1.3 6.8 17.2 1.5 7.0 4.9 3.4 0.0 0.0 6.4 0.0 5.4 1.7 0.0 0.5 14.2 0.0 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.2 0.0 0.0 4.9 1.6 0.0 0.0 9.9 0.0 0.0 0.5 0.0 5.7 0.0 1.9 10.9 0.0 6.0 0.0 1.3 0.0 1.4 0.0 0.1 0.0 1.5 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.4 4.3 0.0 6.5 0.3 0.9 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 3.1 64.2 12.7 16.4 3.5 11.9 5.7 12.3 0.2 6.3 3.4 10.0 0.0 0.6 115.2 0.1 3.6 0.3 0.0 0.6 2.9 0.1 0.3 21.3 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 55.2 0.6 9.8 7.9 0.0 0.0 524.4 0.0 0.1 17.1 1.1 1.5 0.0 24.6 7.1 0.0 0.3 8.4 159.8 0.2 0.0 0.0 1.7 34.0 23.9 0.3 1.8 152.7 0.6 0.1 0.0 689.7 10.0 0.1 0.0 13.5 0.0 0.6 0.0 0.0 0.0 0.7 6.6 22.5 8.1 0.9 2.2 0.1 2.8 0.4 0.2 1.4 0.2 0.4 OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 1458.0;Inhibitory neurons: 1366.9;Late spermatids: 405.5;Microglial cells: 496.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 12000 "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027375: AB_10600087, HPA027380: AB_10601569, HPA027395: AB_10601554" "unprognostic (8.16e-3)" "unprognostic (1.39e-1)" "unprognostic (5.52e-2)" "unprognostic (3.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (6.59e-2)" "prognostic favorable (5.82e-5)" "unprognostic (1.89e-1)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" 28.7 57.7 19.2 11.1 27.8 18.6 29.0 14.0 50.3 30.6 0.0 20.1 14.2 27.7 54.5 28.7 22.4 22.1 30.5 25.7 4.3 29.7 38.3 20.0 14.4 19.2 6.4 27.0 17.1 23.9 12.2 17.0 21.3 21.1 21.7 79.5 48.6 47.6 52.1 27.4 12.2 21.7 1.8 19.5 27.3 56.1 10.7 22.2 21.3 59.6 16.4 23.7 17.9 22.2 29.5 11.0 32.3 6.5 41.2 51.4 15.0 23.7 28.3 21.6 27.5 9.7 35.6 29.6 26.8 25.6 13.2 20.4 18.5 21.2 37.3 24.9 20.0 39.8 15.3 18.0 25.5 12.8 22.8 30.3 32.1 23.7 34.9 30.0 24.7 24.2 20.3 106.5 24.6 26.2 38.3 17.3 4.2 43.5 19.4 9.9 25.7 55.7 24.0 36.8 19.4 6.0 10.5 7.3 25.8 14.1 34.1 21.2 18.4 24.6 17.1 22.6 15.6 19.7 13.3 12.1 29.2 3.7 30.9 38.1 9.3 17.8 3.9 17.6 6.5 11.4 6.7 6.2 11.2 7.9 16.0 7.1 4.7 11.0 19.4 7.9 5.2 7.8 19.2 27.8 14.0 50.3 25.7 4.3 19.2 6.4 21.3 1.8 10.7 22.2 54.9 67.3 25.5 125.0 47.1 67.6 57.2 42.6 60.9 89.8 36.7 33.5 58.2 15.7 37.3 35.0 58.4 32.6 44.1 44.3 33.2 16.6 231.2 75.3 32.1 41.8 27.5 19.5 1458.0 17.0 20.0 41.3 39.8 65.3 30.4 29.1 44.6 34.5 19.5 26.9 1366.9 28.2 34.6 33.0 41.4 405.5 34.2 36.3 24.9 496.5 41.1 55.6 22.6 294.0 142.6 23.6 24.9 48.9 73.7 60.4 16.5 16.4 53.5 125.8 19.7 46.4 41.6 140.4 51.6 56.7 75.6 71.1 26.5 33.5 26.4 86.1 ABRA STARS ENSG00000174429 "Actin binding Rho activating protein" Q8N0Z2 8 106759483-106770244 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Actin-binding, Activator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 31.5;skeletal muscle: 145.0;tongue: 63.8" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 206.4;Early spermatids: 132.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "unprognostic (9.08e-3)" "unprognostic (1.61e-2)" "unprognostic (3.26e-1)" "unprognostic (4.32e-2)" "unprognostic (1.86e-1)" "unprognostic (2.64e-2)" "unprognostic (1.35e-2)" "unprognostic (6.84e-2)" "unprognostic (2.69e-1)" "unprognostic (2.09e-1)" "unprognostic (2.69e-1)" "unprognostic (1.15e-2)" "unprognostic (4.34e-1)" "unprognostic (6.21e-3)" 0.4 0.3 0.0 0.1 0.1 0.0 0.1 1.9 0.3 0.4 0.0 0.1 0.0 1.1 0.1 3.0 0.4 0.1 31.5 0.2 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 1.2 0.1 145.0 0.1 0.0 0.9 0.0 0.1 0.1 2.2 0.0 0.0 0.1 63.8 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.3 0.2 0.0 0.2 0.2 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 206.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 132.8 0.1 0.0 0.9 0.0 0.0 0.3 0.0 0.0 4.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 14.8 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.7 0.0 22.5 3.6 3.3 0.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 ANGPT1 "Ang1, KIAA0003" ENSG00000154188 "Angiopoietin 1" Q15389 8 107249482-107498055 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 33.5" "Group enriched" "Detected in many" 4 "Astrocytes: 60.4;Fibroblasts: 20.4;Inhibitory neurons: 37.6;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.8" "Cell line enhanced" "Detected in many" "ASC diff: 87.9;HEL: 53.1;HSkMC: 145.5;U-138 MG: 70.5;WM-115: 47.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017815, HPA018793, HPA018816" Approved "Secreted to blood" NA NA 32000000 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "CAB017815: , HPA018793: AB_1844820, HPA018816: AB_1844821" "unprognostic (7.71e-2)" "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (4.11e-3)" "unprognostic (7.36e-2)" "unprognostic (3.80e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (1.07e-2)" "unprognostic (5.54e-2)" "unprognostic (2.62e-1)" "unprognostic (1.44e-1)" "prognostic favorable (4.40e-4)" "unprognostic (4.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" 25.1 5.6 3.2 2.6 4.5 0.7 4.6 4.5 2.2 5.8 2.5 3.4 2.3 3.5 4.8 3.5 3.0 13.2 4.8 4.5 6.1 11.1 2.1 21.7 1.4 8.0 3.5 9.5 1.6 1.2 5.8 20.5 4.8 17.7 3.3 0.6 12.0 33.5 23.4 1.2 2.6 3.3 4.8 11.0 4.0 2.3 2.1 2.1 3.5 7.0 1.0 3.9 3.7 11.9 0.0 2.4 9.3 5.3 87.9 30.2 6.6 30.0 25.8 8.1 11.9 6.2 0.1 0.0 0.1 16.0 0.0 0.0 4.2 0.1 10.5 0.0 1.4 53.1 0.6 0.0 24.5 0.7 0.0 145.5 0.0 4.9 0.6 7.5 0.6 0.0 28.2 5.1 10.9 0.0 1.1 7.9 9.6 0.0 1.1 0.0 0.0 3.1 0.0 0.0 0.1 4.2 1.1 0.6 0.0 11.6 2.2 0.0 0.3 70.5 0.9 2.5 0.7 0.2 3.2 0.0 9.7 1.1 47.5 0.1 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.8 0.1 0.3 0.0 0.0 0.6 3.2 4.5 4.5 2.2 4.5 6.1 8.0 3.5 4.8 4.8 2.1 11.9 9.0 0.0 2.3 60.4 0.0 0.6 10.1 0.4 5.2 0.9 0.5 2.8 3.3 0.0 2.2 7.3 0.0 5.2 0.0 0.0 1.9 0.3 8.1 0.7 9.1 5.6 0.0 10.1 6.5 0.0 7.6 20.4 1.5 1.9 0.0 0.0 3.3 0.1 0.5 0.0 37.6 0.0 2.0 0.3 1.0 2.4 2.5 2.9 0.0 6.5 1.5 0.5 0.0 3.0 0.6 0.0 0.0 3.8 1.1 1.2 0.0 2.8 0.8 0.0 6.6 3.5 48.6 1.6 5.4 4.0 0.1 2.7 0.8 1.7 0.1 1.2 RSPO2 MGC35555 ENSG00000147655 "R-spondin 2" Q6UXX9 8 107899316-108083642 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" "Developmental protein, Heparin-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.0;intestine: 13.9;placenta: 17.3" "Group enriched" "Detected in some" 8 "Excitatory neurons: 75.3;Inhibitory neurons: 86.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.2;U-266/70: 4.2" "Group enriched" "Detected in many" 7 "amygdala: 7.9;cerebral cortex: 17.9;hippocampal formation: 21.3;white matter: 13.2" "Group enriched" "Detected in many" 4 "amygdala: 8.3;cerebral cortex: 7.7;hippocampal formation: 8.5;midbrain: 12.9;spinal cord: 7.7" "HPA024764, CAB025900, HPA053068" Uncertain "Secreted in other tissues" NA NA "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB025900: , HPA024764: AB_10603236, HPA053068: AB_2682031" "unprognostic (1.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.97e-2)" "unprognostic (1.52e-1)" "unprognostic (2.04e-1)" "unprognostic (1.19e-1)" "unprognostic (8.33e-3)" "unprognostic (1.82e-1)" "unprognostic (9.48e-2)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (8.45e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" 0.2 0.0 2.8 0.7 4.4 0.1 0.0 1.3 16.2 3.4 2.6 13.9 3.4 0.0 1.7 5.9 0.0 3.2 0.2 6.6 13.2 0.0 0.4 7.1 0.0 2.6 23.0 0.3 0.0 0.0 2.9 17.3 2.0 8.7 7.8 0.3 0.0 2.3 0.0 0.0 4.6 0.3 2.1 0.0 7.6 0.7 3.5 0.0 0.0 0.0 0.0 1.7 0.8 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 4.4 1.3 16.2 6.6 13.2 2.6 23.0 2.0 2.1 3.5 6.6 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 75.3 0.0 0.3 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 86.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 4.7 0.0 0.0 0.0 4.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.6 0.0 1.7 0.0 0.0 1.0 0.0 0.2 0.0 0.0 EIF3E "eIF3-p48, EIF3S6, INT6" ENSG00000104408 "Eukaryotic translation initiation factor 3 subunit E" P60228 8 108162787-108443496 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023973 Approved Supported Cytosol NA NA 21000 "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "HPA023973: AB_1848083" "unprognostic (8.18e-2)" "unprognostic (4.28e-2)" "unprognostic (6.26e-2)" "unprognostic (1.51e-1)" "unprognostic (3.52e-3)" "unprognostic (6.93e-3)" "unprognostic (2.29e-2)" "unprognostic (2.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.96e-1)" "unprognostic (1.67e-3)" "unprognostic (3.63e-1)" "prognostic unfavorable (3.06e-7)" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (2.77e-2)" 269.0 201.4 104.7 94.2 107.2 251.7 418.1 113.6 178.1 360.4 110.9 281.2 93.5 232.5 243.3 256.3 263.0 163.5 187.7 104.6 110.0 178.0 199.1 174.2 231.1 107.7 108.9 449.4 409.1 138.5 157.2 161.1 111.2 204.8 155.7 63.6 214.1 186.4 343.2 230.9 181.7 135.6 107.3 157.6 237.0 83.9 107.6 283.0 183.9 241.1 208.9 248.7 267.2 112.7 339.4 208.1 211.3 193.3 518.2 1098.8 139.9 193.0 430.3 415.4 443.0 238.0 260.1 653.0 213.0 288.6 134.2 187.6 421.1 507.6 502.6 216.1 485.0 595.8 218.6 472.3 357.6 287.5 169.0 813.2 745.9 272.8 678.6 534.7 636.8 405.6 477.5 196.8 469.6 453.7 384.2 898.4 196.2 577.7 403.6 300.6 278.8 436.6 520.0 305.2 223.5 192.2 122.0 78.0 363.2 288.2 263.8 413.7 279.1 131.7 241.7 139.9 201.9 167.4 171.6 426.5 171.6 483.1 149.8 79.5 165.6 32.6 104.0 161.0 197.1 214.7 205.5 148.4 218.7 178.0 301.0 225.9 14.6 166.8 153.1 116.6 202.5 317.3 104.7 107.2 113.6 178.1 104.6 110.0 107.7 108.9 111.2 107.3 107.6 112.7 216.8 134.6 204.6 36.9 565.3 1036.0 1105.8 1174.4 805.3 64.5 569.8 274.2 93.1 317.4 463.5 158.2 54.2 614.4 288.0 101.3 606.5 332.3 377.4 173.8 399.2 365.6 297.5 319.8 36.3 354.3 770.9 366.9 196.7 220.5 378.3 277.1 403.4 212.6 424.2 58.9 36.2 400.5 443.5 662.4 875.2 73.8 454.2 368.7 517.6 37.5 621.8 154.8 268.8 59.8 69.2 272.3 279.1 327.6 251.0 728.2 273.8 799.7 201.7 74.6 190.7 434.6 564.5 276.7 102.8 532.6 1117.1 620.3 488.1 490.0 568.6 914.3 EMC2 "KIAA0103, TTC35" ENSG00000104412 "ER membrane protein complex subunit 2" Q15006 8 108443601-108489196 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 190.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022838 Approved NA NA 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA022838: AB_2670967" "prognostic unfavorable (2.64e-4)" "unprognostic (1.45e-1)" "unprognostic (3.52e-1)" "unprognostic (1.33e-2)" "unprognostic (1.54e-1)" "unprognostic (6.64e-2)" "unprognostic (1.10e-1)" "unprognostic (7.87e-2)" "unprognostic (4.36e-1)" "unprognostic (5.46e-2)" "unprognostic (5.76e-2)" "unprognostic (5.53e-2)" "unprognostic (1.74e-1)" "unprognostic (1.66e-1)" "unprognostic (1.68e-1)" "unprognostic (2.22e-1)" "unprognostic (4.15e-3)" 40.8 38.2 20.1 5.3 21.4 3.5 36.7 20.7 25.3 33.9 19.7 42.9 6.0 27.7 10.1 39.8 31.0 6.7 49.0 19.3 20.4 40.1 34.6 35.5 6.2 21.9 20.2 29.5 41.0 9.6 32.3 9.3 21.3 27.2 8.5 10.2 33.0 7.5 57.3 30.9 27.6 7.3 21.0 26.6 35.1 38.7 20.0 4.6 30.2 10.9 6.1 33.7 33.8 26.3 10.5 5.8 5.0 6.0 9.0 10.1 4.5 4.1 6.5 7.1 6.5 4.8 6.7 4.9 8.7 6.8 5.2 4.6 9.8 10.7 9.0 10.4 9.7 7.9 12.0 7.0 13.7 4.6 4.8 10.7 13.2 6.1 12.0 10.9 9.3 5.6 7.3 5.2 9.4 11.8 6.4 7.0 4.6 17.1 9.9 2.8 6.0 8.0 16.0 5.6 5.4 3.4 4.8 1.3 10.0 7.4 8.3 7.7 5.4 5.0 4.4 9.2 5.4 5.3 11.8 4.9 12.6 10.8 7.7 11.6 6.1 10.4 9.0 5.9 8.1 6.3 8.1 10.7 6.3 6.0 9.6 9.6 7.9 6.9 6.8 10.3 8.5 5.6 20.1 21.4 20.7 25.3 19.3 20.4 21.9 20.2 21.3 21.0 20.0 26.3 47.3 32.1 49.5 50.9 22.8 27.5 52.5 157.7 27.3 17.9 18.6 20.8 66.8 37.1 98.7 36.8 14.6 57.2 25.8 19.8 86.1 52.0 72.8 48.4 28.4 37.4 21.1 9.9 30.9 46.5 47.6 43.9 17.3 28.7 35.5 20.8 32.9 24.7 47.7 18.5 37.8 23.6 93.6 20.5 16.1 24.6 36.7 21.3 32.0 24.4 38.6 57.9 16.5 44.7 102.1 34.2 27.5 37.2 27.6 31.4 40.3 102.4 98.6 30.5 65.7 39.3 64.6 190.8 71.6 20.5 27.3 73.5 24.4 45.9 22.2 42.5 TMEM74 "FLJ30668, NET36" ENSG00000164841 "Transmembrane protein 74" Q96NL1 8 108606850-108787594 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.2" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 4.6;Bipolar cells: 4.7;Cone photoreceptor cells: 6.2;Excitatory neurons: 5.1;Muller glia cells: 3.3;Rod photoreceptor cells: 8.3;Spermatogonia: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.7;JURKAT: 1.5;NTERA-2: 2.1;RH-30: 1.5;SCLC-21H: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015672, HPA076461" Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Cytosol" "HPA015672: AB_1858132, HPA076461: " "unprognostic (8.99e-2)" "unprognostic (1.18e-1)" "unprognostic (4.25e-2)" "unprognostic (6.33e-2)" "unprognostic (2.05e-1)" "unprognostic (4.18e-1)" "unprognostic (1.95e-2)" "unprognostic (1.00e-1)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (2.01e-2)" "unprognostic (3.97e-2)" "unprognostic (3.75e-4)" "unprognostic (8.77e-2)" "unprognostic (6.36e-2)" "unprognostic (5.95e-2)" "unprognostic (1.46e-3)" 0.3 0.2 1.8 0.1 2.2 0.0 0.2 4.7 2.4 0.2 1.4 1.3 0.0 0.1 0.0 0.5 0.1 0.1 1.3 3.7 3.0 0.1 0.8 0.1 0.0 3.8 1.7 0.1 0.5 0.0 0.4 0.0 3.5 0.1 0.1 2.5 0.2 0.1 0.8 0.3 0.2 0.4 6.1 0.1 0.3 0.3 1.6 0.3 0.1 0.2 0.1 0.2 0.4 8.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.1 1.7 0.7 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.9 0.0 1.5 0.0 0.0 0.0 5.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.5 0.7 0.0 0.1 0.2 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.2 4.7 2.4 3.7 3.0 3.8 1.7 3.5 6.1 1.6 8.2 0.4 0.0 0.0 2.0 0.0 0.9 0.7 0.0 4.6 4.7 0.2 0.6 0.8 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.3 1.8 0.0 5.1 0.2 0.8 0.7 0.0 0.1 0.0 0.5 0.0 0.7 0.1 0.0 2.0 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.0 0.0 3.3 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 8.3 0.0 0.8 0.9 0.2 4.1 2.0 0.6 0.1 0.1 0.1 0.0 0.0 TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086585-109121565 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055162 Approved NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA055162: AB_2732592" "unprognostic (1.92e-2)" "unprognostic (8.58e-2)" "unprognostic (1.17e-1)" 0.0 0.0 3.2 0.0 0.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.4 0.0 0.0 0.0 0.0 0.9 1.2 0.0 0.0 0.0 0.6 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 5.2 3.4 1.4 0.9 1.2 1.2 1.7 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NUDCD1 "CML66, FLJ14991" ENSG00000120526 "NudC domain containing 1" Q96RS6 8 109240919-109334121 "Predicted intracellular proteins" Immunity "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023183 Uncertain Supported Nucleoplasm,Cytosol NA NA 7300 "Cluster 39: Non-specific - mRNA processing" "Cluster 28: Placenta - Pregnancy" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm Cytosol "HPA023183: AB_1854695" "unprognostic (5.08e-3)" "unprognostic (3.73e-2)" "unprognostic (2.52e-2)" "unprognostic (9.03e-3)" "unprognostic (7.52e-2)" "unprognostic (3.62e-3)" "prognostic unfavorable (1.39e-5)" "prognostic unfavorable (4.37e-5)" "unprognostic (2.13e-1)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (8.22e-2)" "prognostic unfavorable (8.71e-6)" "unprognostic (1.95e-1)" "unprognostic (1.63e-1)" "unprognostic (3.35e-1)" "unprognostic (1.65e-1)" 11.1 5.0 3.3 6.0 3.5 1.3 9.5 3.7 4.2 7.7 3.1 5.5 2.8 7.2 5.2 5.7 6.9 4.8 6.6 3.3 3.5 7.8 6.4 7.0 9.3 3.7 3.6 6.3 6.9 5.8 4.2 15.1 3.4 5.9 6.7 4.7 6.1 6.8 6.1 4.3 5.1 7.9 4.1 7.3 5.8 13.0 3.4 10.1 9.0 9.3 8.5 11.4 6.8 3.8 28.9 16.7 24.7 13.7 13.1 18.0 13.1 20.6 24.8 57.8 54.4 17.6 21.8 18.5 13.1 22.5 16.3 17.1 36.3 34.3 79.8 23.6 12.6 28.8 9.9 19.6 27.2 13.7 10.6 12.7 18.4 28.1 40.3 18.3 53.0 22.7 32.2 9.5 49.5 23.3 33.3 15.1 17.3 59.7 22.7 21.4 20.4 18.3 35.6 14.8 20.5 18.1 9.4 26.1 21.6 25.6 19.2 9.9 14.2 28.2 17.2 12.1 17.6 6.9 9.4 22.3 10.4 22.2 24.1 0.0 0.4 0.5 0.8 1.3 1.4 1.2 1.0 1.6 1.4 1.1 1.1 1.6 0.0 1.7 1.7 0.9 1.5 0.7 3.3 3.5 3.7 4.2 3.3 3.5 3.7 3.6 3.4 4.1 3.4 3.8 25.4 3.2 10.0 6.2 11.3 17.7 24.4 19.4 10.2 5.0 7.4 6.3 11.3 2.8 23.2 3.7 6.2 23.4 9.7 2.5 7.9 17.1 122.3 11.2 19.2 26.5 9.0 14.5 22.9 11.0 21.2 16.2 5.6 10.2 17.7 11.8 8.9 6.2 9.8 5.0 23.5 5.7 14.2 4.7 11.5 22.5 13.1 8.7 7.2 13.1 16.9 4.4 5.2 15.1 15.3 14.1 4.7 6.8 12.1 29.6 3.4 13.0 15.4 9.0 0.0 13.7 15.8 53.3 36.4 8.9 16.8 8.2 9.5 12.5 9.9 22.7 ENY2 "DC6, FLJ20480, Sus1" ENSG00000120533 "ENY2 transcription and export complex 2 subunit" Q9NPA8 8 109334324-109345954 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Transcription, Transcription regulation, Translocation, Transport" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024648 Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Mitochondria" "HPA024648: AB_2100208" "unprognostic (2.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.18e-1)" "unprognostic (7.85e-2)" "unprognostic (7.70e-2)" "unprognostic (7.45e-3)" "unprognostic (1.48e-2)" "unprognostic (6.65e-2)" "unprognostic (2.54e-1)" "unprognostic (1.21e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "prognostic unfavorable (7.17e-6)" "unprognostic (1.74e-1)" "unprognostic (1.51e-1)" "unprognostic (8.84e-2)" "unprognostic (2.66e-1)" 54.4 55.5 28.1 44.7 29.1 87.6 57.0 29.3 45.3 44.2 32.9 59.5 54.5 37.9 53.8 48.2 36.1 29.9 64.2 29.1 32.2 74.4 101.3 40.4 49.6 31.5 30.5 29.5 44.9 47.2 34.4 41.3 30.1 39.0 55.1 24.5 43.7 36.0 71.7 34.7 47.9 44.1 29.8 47.7 47.9 34.8 29.7 60.3 38.0 68.5 53.8 48.4 38.9 30.9 180.3 145.9 213.6 97.1 79.5 101.0 61.4 140.0 89.9 141.2 177.2 109.0 109.1 115.3 127.9 110.9 63.6 89.7 96.8 99.5 171.7 184.1 113.9 223.5 106.7 227.4 85.4 78.3 133.5 77.5 66.7 92.5 87.3 102.2 215.1 111.5 216.5 63.7 162.7 289.9 235.9 175.5 156.1 207.1 140.3 148.4 93.2 144.5 192.5 134.7 128.9 137.5 87.7 109.3 127.2 117.0 138.6 132.3 146.9 94.1 158.9 97.8 144.7 107.9 125.6 222.2 95.2 128.3 112.7 65.6 102.5 93.5 28.9 112.8 36.7 41.4 39.0 35.6 93.8 27.3 31.9 35.8 56.8 42.4 121.8 80.3 42.3 74.5 28.1 29.1 29.3 45.3 29.1 32.2 31.5 30.5 30.1 29.8 29.7 30.9 231.3 70.5 93.8 16.3 135.0 185.6 196.3 305.7 159.9 63.8 149.2 192.7 170.6 138.7 184.6 145.3 123.0 263.3 157.0 171.5 381.5 214.3 173.3 146.4 134.7 226.3 154.2 160.1 22.7 200.0 284.5 161.0 88.7 144.8 91.8 99.3 142.5 371.1 276.8 45.4 23.9 245.1 225.9 230.3 265.7 111.0 148.2 205.0 158.3 17.8 260.9 112.4 126.7 19.6 27.6 251.2 237.1 112.5 147.2 230.3 264.5 546.1 125.0 139.9 78.9 163.9 262.9 208.7 130.4 151.0 174.6 167.3 132.4 143.9 209.1 208.0 PKHD1L1 ENSG00000205038 "PKHD1 like 1" Q86WI1 8 109362461-109537207 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 25.5;thyroid gland: 68.8" "Cell type enhanced" "Detected in some" "B-cells: 24.4;Endometrial ciliated cells: 47.0;Endothelial cells: 14.0;Glandular and luminal cells: 49.9;Plasma cells: 28.2" "Group enriched" "Detected in some" 18 "endometrial cancer: 5.2;ovarian cancer: 1.9;thyroid cancer: 3.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.0;HHSteC: 1.4;TIME: 1.6;U-266/70: 3.9" "Not detected" "Not detected" HPA044458 Uncertain NA NA 13000000 "Cluster 1: Thyroid gland - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "HPA044458: AB_2678949" "unprognostic (9.07e-3)" "unprognostic (3.35e-2)" "unprognostic (1.37e-2)" "prognostic favorable (7.61e-4)" "unprognostic (5.57e-2)" "unprognostic (1.30e-2)" "unprognostic (2.91e-2)" "unprognostic (3.45e-2)" "unprognostic (3.31e-2)" "unprognostic (1.98e-1)" "unprognostic (9.65e-3)" "unprognostic (1.92e-1)" "unprognostic (7.76e-6)" "unprognostic (4.56e-2)" "unprognostic (1.52e-1)" "unprognostic (1.90e-3)" "unprognostic (2.73e-2)" 25.5 2.7 0.2 0.5 0.2 0.4 2.6 0.1 0.2 13.7 1.4 2.6 1.1 5.9 0.3 1.7 14.1 0.4 9.3 0.1 0.3 1.9 0.6 6.9 1.2 0.2 0.2 2.6 0.5 0.0 0.8 0.0 0.1 0.7 1.6 0.0 0.7 0.2 0.2 1.7 4.3 0.4 0.1 0.5 1.6 0.5 0.1 0.1 68.8 0.6 1.1 1.2 1.5 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.2 0.1 0.3 0.2 0.2 0.1 0.1 0.1 0.4 1.3 0.0 2.8 0.7 24.4 0.3 0.0 0.0 0.6 0.0 0.1 0.0 1.9 1.5 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 47.0 3.4 14.0 1.8 0.4 0.2 0.0 0.1 6.6 1.1 49.9 1.3 0.0 10.4 0.6 0.0 0.0 0.2 0.0 0.0 0.9 0.3 0.5 0.6 0.3 1.8 1.9 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 28.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.6 0.0 1.9 0.0 0.1 0.0 EBAG9 "EB9, RCAS1" ENSG00000147654 "Estrogen receptor binding site associated antigen 9" O00559 8 109539711-109565996 "Cancer-related genes, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021153, HPA021154, CAB072810, CAB072811, CAB072812" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus" "CAB072810: , CAB072811: , CAB072812: , HPA021153: AB_1856151, HPA021154: AB_1856152" "unprognostic (3.04e-2)" "unprognostic (9.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.99e-1)" "unprognostic (5.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.63e-1)" "unprognostic (3.17e-2)" "unprognostic (1.72e-1)" "unprognostic (4.22e-2)" "unprognostic (1.04e-1)" "unprognostic (3.72e-1)" "unprognostic (9.72e-3)" "unprognostic (6.46e-2)" "unprognostic (5.16e-1)" "unprognostic (3.53e-1)" "unprognostic (3.71e-2)" 23.3 28.4 18.6 17.6 19.9 16.9 32.4 23.4 26.3 36.1 19.8 28.6 23.5 22.8 44.7 17.0 27.6 19.4 24.7 19.1 20.5 37.0 45.2 28.1 25.4 18.9 19.0 22.2 36.7 34.9 20.5 18.1 19.0 23.3 31.2 32.5 42.9 27.6 53.2 17.9 21.0 17.0 19.1 20.7 27.2 25.3 19.3 20.6 57.4 42.3 27.0 17.2 15.3 20.2 36.7 25.2 25.3 17.3 15.3 24.9 19.7 19.5 14.6 27.0 25.4 25.7 38.1 51.7 33.0 13.8 21.8 25.2 24.4 31.3 28.5 57.6 26.9 56.9 15.8 39.6 34.3 20.0 16.1 19.9 60.1 23.4 47.2 21.9 25.7 45.8 59.8 37.0 24.0 55.8 58.2 31.5 15.8 70.1 25.2 30.9 20.1 43.7 31.4 23.7 27.6 22.1 21.3 22.6 27.6 18.4 44.7 25.6 17.5 20.9 15.0 19.1 14.4 54.9 38.3 48.7 21.2 52.7 19.6 5.8 13.4 14.7 19.3 19.5 34.1 40.7 27.1 27.0 22.5 40.3 33.5 30.4 2.8 29.4 17.3 23.8 33.4 14.7 18.6 19.9 23.4 26.3 19.1 20.5 18.9 19.0 19.0 19.1 19.3 20.2 32.0 121.8 102.4 12.7 40.2 21.7 28.6 51.8 44.9 34.5 36.8 46.0 37.6 54.3 65.1 29.5 6.2 50.2 24.0 33.6 64.6 47.3 134.7 42.9 26.7 34.5 31.8 36.0 16.1 65.8 34.0 28.8 22.4 33.0 46.9 16.0 23.2 48.8 32.7 50.5 16.1 39.4 50.8 24.7 22.1 115.0 29.2 27.9 19.6 11.2 25.3 53.4 27.8 18.1 16.1 38.5 41.3 23.0 53.8 36.8 50.5 58.5 61.8 34.7 32.9 35.1 32.1 101.6 50.4 40.5 19.9 22.2 28.5 34.7 46.0 31.7 SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 140.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 200.5;Horizontal cells: 95.9;Inhibitory neurons: 129.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.4;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.4" "Cell line enhanced" "Detected in many" "HaCaT: 24.4;PC-3: 25.7;SK-BR-3: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA053057: AB_2682028" "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favorable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" 32.2 38.7 39.1 3.2 42.0 0.0 22.2 44.5 52.4 10.7 4.4 15.4 10.9 5.6 11.5 5.6 20.1 10.3 6.9 42.4 58.6 4.2 52.1 8.8 4.4 24.2 34.0 9.2 140.5 1.5 30.4 2.5 36.6 8.2 19.7 26.1 21.5 11.0 3.8 9.6 12.0 6.9 22.8 1.0 28.2 1.8 50.8 5.4 12.3 7.7 7.8 5.9 8.8 30.2 8.6 5.2 3.6 0.0 0.5 0.6 2.5 3.1 0.0 0.0 0.0 7.9 5.4 0.7 0.5 2.5 1.2 24.4 0.8 5.7 0.0 0.1 11.6 0.0 15.2 8.2 6.2 0.0 0.0 1.9 7.7 0.0 7.2 0.4 3.3 0.6 0.4 1.6 3.5 0.2 0.2 0.0 0.7 7.7 25.7 0.0 0.0 0.0 9.5 2.2 16.3 1.9 6.9 51.4 1.7 2.5 6.8 0.3 5.0 0.3 2.0 0.1 1.5 1.5 0.1 0.5 10.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 6.4 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 39.1 42.0 44.5 52.4 42.4 58.6 24.2 34.0 36.6 22.8 50.8 30.2 39.3 9.6 7.7 16.0 4.3 5.7 2.5 8.3 17.1 46.1 10.9 9.1 2.4 30.0 18.0 11.0 8.4 4.6 0.1 3.6 3.9 5.4 1.4 29.3 3.4 11.8 34.5 0.0 200.5 9.4 0.9 7.9 5.6 20.9 0.0 0.7 10.0 39.1 0.3 95.9 129.6 22.2 2.0 0.8 4.2 0.4 2.1 0.3 1.8 21.5 0.7 2.1 0.0 22.1 5.7 3.9 9.8 0.4 0.1 11.8 16.2 0.1 15.6 7.4 0.0 16.5 4.2 1.3 1.5 3.5 3.3 0.7 0.6 0.1 13.7 4.2 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 6.8" "Group enriched" "Detected in some" 12 "Excitatory neurons: 915.9;Inhibitory neurons: 867.9;Oligodendrocyte precursor cells: 1761.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029007: AB_10601802, HPA029008: " "unprognostic (2.26e-1)" "unprognostic (2.16e-2)" "unprognostic (2.83e-2)" "unprognostic (5.97e-2)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (3.54e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-2)" "unprognostic (5.03e-10)" "unprognostic (1.95e-1)" "unprognostic (4.14e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-3)" 0.0 0.0 6.8 0.0 4.3 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 4.8 0.0 0.0 0.0 0.0 1.9 2.7 0.0 0.2 0.0 0.1 0.0 1.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 4.3 0.0 6.0 5.7 4.8 1.9 2.7 1.6 0.8 5.0 0.7 0.0 0.0 3.0 21.5 0.2 0.3 0.1 0.0 0.0 7.3 0.0 0.0 1.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.5 0.1 0.4 0.0 0.0 915.9 0.0 0.0 0.9 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 867.9 0.0 0.0 0.0 0.8 6.3 0.0 0.3 0.0 19.7 0.0 0.5 0.0 1761.3 92.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.9 0.0 0.4 0.2 17.1 8.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "breast: 60.8" "Cell type enhanced" "Detected in many" "Astrocytes: 758.7;Breast glandular cells: 243.2;Oligodendrocyte precursor cells: 280.5;Oligodendrocytes: 294.0" "Cancer enriched" "Detected in many" 8 "breast cancer: 49.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 47.4;SK-BR-3: 78.1;T-47d: 244.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "HPA060380: AB_2684270, HPA071767: AB_2732185" "unprognostic (4.34e-2)" "unprognostic (4.65e-2)" "unprognostic (1.73e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "prognostic favorable (9.42e-4)" "unprognostic (2.23e-3)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (3.02e-1)" "unprognostic (2.17e-2)" "unprognostic (1.93e-2)" "unprognostic (1.64e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-3)" 4.4 3.1 15.5 5.7 14.3 7.6 60.8 10.5 14.7 10.9 10.1 5.9 0.9 9.9 3.4 14.2 5.5 10.0 3.8 17.0 13.5 5.4 2.1 4.7 4.9 32.5 31.5 5.2 1.1 5.3 2.6 2.8 24.2 9.4 2.7 4.1 12.0 8.4 2.6 10.6 2.1 10.6 18.4 4.2 2.7 12.5 27.5 2.4 5.7 3.3 4.0 5.1 14.1 16.3 3.1 0.6 5.9 0.3 5.4 19.8 0.6 4.9 11.3 3.1 5.2 0.5 4.9 2.4 0.0 12.7 2.6 0.1 22.9 4.3 3.5 0.3 6.9 0.1 10.3 0.2 7.2 0.0 0.3 9.5 4.4 8.6 15.8 8.9 2.7 0.3 1.1 37.7 6.0 47.4 0.2 0.0 1.1 1.1 4.8 0.2 0.2 30.0 4.9 0.3 5.2 3.9 2.5 78.1 3.2 2.8 244.8 2.1 0.2 13.7 6.9 4.0 9.7 10.1 0.3 4.5 14.4 0.0 9.2 0.0 4.5 0.0 0.9 1.9 0.9 0.5 1.0 1.0 1.7 0.8 0.9 0.9 0.8 1.0 1.4 0.6 0.5 0.8 15.5 14.3 10.5 14.7 17.0 13.5 32.5 31.5 24.2 18.4 27.5 16.3 10.0 6.4 3.0 758.7 13.3 9.4 20.0 10.3 34.1 9.2 243.2 125.1 4.6 2.8 9.2 18.4 43.8 0.1 18.7 0.1 11.7 2.9 95.0 58.5 35.7 7.5 0.0 5.5 128.3 2.9 0.2 26.8 4.6 63.5 12.7 0.3 3.6 1.1 16.5 0.0 148.2 0.0 8.2 55.2 104.1 163.2 25.1 55.5 21.4 171.4 32.5 10.6 5.2 280.5 294.0 2.7 0.0 28.2 10.1 16.9 0.0 23.7 8.9 35.9 6.6 60.2 28.2 1.8 8.3 73.6 12.5 0.3 25.6 19.5 0.0 11.2 EIF3H "eIF3-gamma, eIF3-p40, EIF3S3" ENSG00000147677 "Eukaryotic translation initiation factor 3 subunit H" O15372 8 116642130-116766925 "Cancer-related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 1808.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023117, HPA023553" Approved Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "HPA023117: AB_1848076, HPA023553: AB_1848077" "prognostic unfavorable (5.26e-4)" "prognostic unfavorable (8.07e-4)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (8.34e-4)" "unprognostic (3.63e-2)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "unprognostic (1.12e-3)" "unprognostic (3.08e-1)" "unprognostic (3.77e-2)" "unprognostic (6.36e-2)" "unprognostic (1.48e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-1)" 212.3 164.1 111.0 168.6 119.8 341.1 246.8 114.8 138.5 270.2 104.2 233.1 172.7 212.7 180.0 232.0 211.3 159.2 223.6 106.9 121.0 184.2 181.0 149.2 283.2 118.4 113.7 392.6 249.9 184.0 147.6 161.7 120.6 179.5 201.9 131.0 219.9 158.1 372.6 201.8 167.9 182.5 124.2 171.4 195.2 144.4 111.9 291.0 215.5 278.3 307.1 221.7 237.0 130.2 455.0 256.2 302.2 264.9 390.3 678.0 300.4 292.5 374.4 316.7 306.5 266.1 521.6 719.4 288.6 307.2 230.4 284.4 335.5 445.2 395.5 468.5 271.9 636.0 212.0 400.6 487.8 278.1 325.7 630.0 606.4 287.0 659.5 536.4 348.8 555.5 548.2 370.1 360.4 335.7 778.2 388.1 308.6 995.6 404.5 443.6 201.8 517.6 479.8 327.8 341.6 412.4 153.5 1808.1 504.9 294.8 538.3 550.5 322.5 201.8 374.5 301.5 388.8 591.3 574.4 591.3 280.2 483.4 281.8 165.2 361.6 132.2 217.9 356.8 358.9 438.1 393.5 317.9 468.6 381.4 511.0 432.1 74.4 314.6 366.1 260.9 477.7 585.7 111.0 119.8 114.8 138.5 106.9 121.0 118.4 113.7 120.6 124.2 111.9 130.2 138.9 182.7 210.7 42.4 314.6 337.5 423.7 444.2 266.9 62.7 317.2 273.4 160.8 191.6 253.0 93.8 12.5 488.0 211.4 117.0 448.0 290.5 387.2 81.2 196.0 185.8 201.0 215.8 47.8 380.5 551.0 183.7 125.9 159.2 194.4 166.2 168.8 104.6 332.4 26.9 49.9 301.6 170.9 386.6 402.8 265.0 331.5 261.5 209.9 51.5 509.9 136.0 224.6 58.3 70.3 292.9 240.5 220.1 166.7 338.5 260.2 443.9 92.9 76.8 197.2 251.5 504.1 233.0 176.0 317.4 356.5 577.2 287.5 241.4 345.5 481.2 UTP23 "C8orf53, MGC14595" ENSG00000147679 "UTP23 small subunit processome component" Q9BRU9 8 116766505-116849463 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044418 Uncertain Approved Nucleoli NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" Nucleoli "HPA044418: AB_10961139" "prognostic unfavorable (5.18e-5)" "unprognostic (2.30e-2)" "unprognostic (3.34e-1)" "unprognostic (1.18e-2)" "unprognostic (2.64e-1)" "unprognostic (7.23e-2)" "unprognostic (9.45e-3)" "unprognostic (7.73e-2)" "unprognostic (7.78e-2)" "unprognostic (1.77e-1)" "unprognostic (1.34e-2)" "unprognostic (8.62e-2)" "unprognostic (1.75e-2)" "unprognostic (5.78e-2)" "unprognostic (2.03e-1)" "unprognostic (7.15e-3)" "unprognostic (9.27e-2)" 11.8 7.9 5.6 10.1 6.6 33.2 9.6 8.1 6.7 7.8 4.3 7.1 6.2 9.6 6.5 7.2 8.1 7.9 7.1 5.7 6.0 6.8 7.4 7.8 15.4 5.6 5.5 13.7 9.7 8.1 4.8 9.6 5.7 8.1 5.6 9.6 9.0 6.4 8.6 8.0 7.8 7.4 6.1 10.3 7.7 6.8 5.4 8.2 12.3 6.2 8.9 7.9 5.9 9.0 22.0 22.7 12.9 11.3 17.9 21.3 9.8 21.9 13.3 14.1 15.6 23.8 14.2 34.4 20.5 10.5 14.1 16.1 18.2 12.8 17.4 33.5 35.3 42.5 18.3 16.2 19.1 21.2 19.7 18.6 13.8 15.7 19.1 9.2 15.4 25.9 27.7 22.6 14.1 38.3 50.2 12.4 11.8 35.9 44.1 28.1 14.2 29.7 8.9 19.8 22.7 18.3 14.2 53.8 21.5 6.5 25.8 14.6 16.4 14.7 20.3 35.7 30.9 30.8 48.9 39.7 18.8 27.4 17.4 49.7 24.6 32.6 39.5 26.6 34.2 43.1 35.2 31.2 22.1 41.6 47.7 33.2 24.6 28.1 37.0 36.1 43.6 26.4 5.6 6.6 8.1 6.7 5.7 6.0 5.6 5.5 5.7 6.1 5.4 9.0 33.6 41.7 33.1 36.2 31.0 21.9 27.0 17.4 31.9 23.2 16.7 29.2 23.4 27.1 23.4 7.3 6.2 28.3 24.8 9.9 27.4 17.3 13.9 18.0 37.0 28.7 12.0 12.4 62.6 20.7 17.9 32.9 21.9 20.6 41.8 24.3 25.0 13.8 16.6 16.8 62.2 16.6 14.2 12.6 10.5 4.8 28.9 18.5 10.6 15.9 24.0 27.4 20.6 42.3 43.0 12.4 9.4 28.6 32.0 28.7 9.0 16.2 19.2 22.4 13.1 39.5 26.4 44.0 20.3 26.6 16.2 19.8 29.5 28.8 16.6 19.1 RAD21 "hHR21, KIAA0078, SCC1" ENSG00000164754 "RAD21 cohesin complex component" O60216 8 116845934-116874776 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Activator, Developmental protein, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 424.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020044, CAB022065, HPA073277" Supported Enhanced Nucleoplasm NA Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "CAB022065: , HPA020044: AB_1856035, HPA073277: " "unprognostic (7.85e-2)" "unprognostic (4.92e-1)" "unprognostic (3.05e-1)" "unprognostic (5.43e-3)" "unprognostic (9.56e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.86e-3)" "unprognostic (8.99e-2)" "unprognostic (8.80e-2)" "unprognostic (5.58e-3)" "unprognostic (3.56e-2)" "unprognostic (4.40e-2)" "unprognostic (2.00e-1)" "unprognostic (1.82e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-1)" 75.4 80.5 62.9 74.0 74.5 206.0 71.9 74.7 75.7 50.5 56.7 73.1 57.3 67.6 54.6 71.2 50.6 49.4 89.8 58.1 74.3 68.2 64.7 67.9 122.8 70.0 69.3 67.8 41.9 82.3 33.8 90.1 75.2 57.5 82.5 114.2 56.9 65.0 76.6 54.0 60.4 60.2 71.9 75.5 56.4 88.7 67.2 177.2 80.9 95.5 119.5 59.7 44.5 97.1 301.6 143.9 277.3 156.7 136.5 117.0 124.2 202.1 191.4 220.8 202.4 119.8 275.2 438.6 109.4 146.0 117.4 162.4 238.5 132.1 257.6 589.1 153.1 447.6 167.2 153.7 85.5 145.7 253.1 100.2 106.0 129.4 156.0 146.1 176.4 625.8 183.6 595.6 193.1 181.1 665.4 86.2 163.6 385.4 179.2 241.8 201.5 223.4 133.5 173.3 348.2 179.1 212.2 569.4 140.6 144.5 238.3 178.5 128.5 154.6 223.5 164.4 217.1 313.3 383.9 391.9 132.8 206.7 189.7 35.3 7.9 28.0 17.4 8.7 17.5 14.4 20.3 20.6 9.0 12.8 20.8 20.6 29.7 14.3 12.7 7.6 43.7 11.4 62.9 74.5 74.7 75.7 58.1 74.3 70.0 69.3 75.2 71.9 67.2 97.1 115.7 256.4 157.1 24.5 111.2 95.6 77.5 62.5 78.0 75.4 65.8 53.0 155.2 51.5 101.0 55.2 31.3 142.4 118.1 90.4 43.0 54.0 258.0 67.0 86.7 97.0 84.4 249.8 39.3 44.9 157.0 89.4 57.1 88.2 153.5 112.9 75.0 72.1 67.9 67.3 48.1 72.7 69.2 93.1 100.0 424.9 116.5 93.4 69.4 45.9 110.8 112.5 77.2 41.2 58.3 63.5 66.3 106.5 124.0 100.0 35.7 59.4 70.5 67.9 72.3 88.6 85.3 33.2 88.6 103.7 100.4 113.7 134.1 85.5 94.1 95.5 AARD "C8orf85, LOC441376" ENSG00000205002 "Alanine and arginine rich domain containing protein" Q4LEZ3 8 116938207-116944487 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.5;urinary bladder: 7.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 27.6;Breast glandular cells: 26.0;Breast myoepithelial cells: 29.0;granulocytes: 14.5;Late spermatids: 18.4;Proximal tubular cells: 14.9;Spermatocytes: 57.4" "Cancer enriched" "Detected in many" 8 "breast cancer: 27.0" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 21.7;JURKAT: 7.2;SK-BR-3: 11.8;U-2 OS: 5.5;U-266/84: 4.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 4 "midbrain: 4.4" HPA068290 Approved "Lipid droplets" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Lipid droplets" "HPA068290: " "unprognostic (5.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.32e-1)" "unprognostic (7.28e-8)" "unprognostic (3.42e-2)" "unprognostic (4.32e-3)" "unprognostic (4.34e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (8.57e-3)" "unprognostic (4.20e-1)" "unprognostic (2.23e-6)" "unprognostic (1.67e-1)" "unprognostic (9.78e-3)" "unprognostic (3.77e-2)" "unprognostic (5.27e-4)" 0.6 0.9 0.5 0.4 0.8 0.2 4.3 0.4 0.9 0.3 0.9 5.9 0.1 0.8 0.2 2.4 0.1 0.2 0.0 0.6 0.6 1.0 0.0 2.5 0.8 1.2 1.0 0.0 0.0 0.0 0.0 0.4 0.9 0.6 0.5 0.1 2.0 0.1 0.1 1.5 1.0 1.0 0.8 0.1 6.8 22.5 0.7 0.0 0.1 0.0 0.4 7.7 0.2 1.3 0.0 0.0 0.5 0.0 0.0 0.0 0.2 1.8 0.3 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 0.5 0.0 0.2 0.1 2.4 0.0 0.2 0.4 0.0 0.1 0.1 0.1 0.0 7.2 0.0 2.4 0.1 0.5 0.9 0.1 1.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 1.9 0.3 0.0 11.8 0.1 0.2 0.5 0.0 0.0 0.1 5.5 0.2 0.0 1.6 4.5 0.0 3.0 0.0 0.3 1.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.7 0.3 0.1 0.2 0.6 0.0 0.5 0.8 0.4 0.9 0.6 0.6 1.2 1.0 0.9 0.8 0.7 1.3 0.2 12.8 27.6 0.0 0.1 0.8 0.6 0.2 0.0 0.4 26.0 29.0 0.9 0.0 5.0 7.3 0.0 0.2 0.8 0.1 1.9 0.1 9.3 0.1 1.7 0.9 0.0 0.0 0.8 0.0 0.9 1.4 0.0 0.0 14.5 0.1 0.0 0.1 0.0 1.7 2.1 0.0 0.0 0.0 0.3 18.4 4.1 0.5 0.0 0.0 0.1 0.1 4.1 0.0 0.2 0.1 0.0 0.7 0.0 0.6 0.0 14.9 0.7 0.2 0.0 0.5 1.1 57.4 7.3 0.0 0.6 0.3 0.8 2.0 0.0 0.4 SLC30A8 "ZnT-8, ZNT8" ENSG00000164756 "Solute carrier family 30 member 8" Q8IWU4 8 116950273-117176714 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pancreas: 61.8" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Late spermatids: 7.5;Pancreatic endocrine cells: 5.0;Proximal tubular cells: 3.6;Spermatogonia: 5.0" "Group enriched" "Detected in some" 28 "breast cancer: 10.6;pancreatic cancer: 15.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 36 "U-266/70: 48.0;U-266/84: 36.2" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 4.1" HPA076165 Enhanced NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "HPA076165: AB_2732304" "unprognostic (2.14e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (5.38e-2)" "unprognostic (5.57e-2)" "unprognostic (4.38e-1)" "unprognostic (3.36e-1)" "unprognostic (1.19e-1)" "unprognostic (6.66e-2)" "unprognostic (6.51e-3)" "unprognostic (2.15e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "unprognostic (9.16e-3)" 0.0 0.0 0.3 0.0 0.4 0.3 0.6 0.2 0.2 0.1 0.0 0.3 0.6 0.7 0.0 0.2 0.1 0.2 0.2 0.3 0.2 4.3 0.0 0.1 0.1 0.2 0.1 0.0 61.8 0.3 0.3 0.3 0.3 0.1 0.2 0.2 12.9 0.0 0.0 0.8 1.0 0.2 0.0 0.0 1.1 2.0 0.1 0.1 0.1 0.0 0.1 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 48.0 36.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.2 0.3 0.2 0.2 0.1 0.3 0.0 0.1 0.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 4.9 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 1.8 5.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 MED30 "THRAP6, TRAP25" ENSG00000164758 "Mediator complex subunit 30" Q96HR3 8 117520713-117540262 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 169.9;Suprabasal keratinocytes: 152.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045767 Approved Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm "HPA045767: AB_2679446" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (3.86e-2)" "unprognostic (1.57e-2)" "unprognostic (1.46e-1)" "unprognostic (3.20e-2)" "unprognostic (2.00e-2)" "unprognostic (3.33e-2)" "unprognostic (8.41e-2)" "unprognostic (4.02e-2)" "unprognostic (1.51e-2)" "unprognostic (7.73e-2)" "prognostic unfavorable (1.70e-6)" "unprognostic (5.38e-3)" "unprognostic (2.80e-1)" "unprognostic (1.05e-1)" "unprognostic (4.62e-2)" 18.4 9.4 10.7 11.6 11.4 44.6 17.6 11.4 14.4 15.5 10.1 14.6 9.3 15.7 8.3 12.6 18.4 6.6 11.0 10.4 10.6 8.2 15.2 13.0 17.3 11.1 10.8 20.1 9.1 7.3 10.0 11.4 11.1 11.4 11.6 5.0 9.7 10.3 10.4 17.0 12.4 9.3 11.5 14.0 11.2 11.4 10.9 25.1 12.1 10.4 15.3 13.3 14.9 12.7 54.0 5.6 20.8 13.9 14.2 13.3 22.9 15.9 16.9 23.8 29.4 10.2 26.2 42.7 24.7 8.7 18.3 23.7 18.6 12.4 30.4 57.4 23.0 34.7 3.2 13.2 15.6 27.7 28.9 12.3 13.8 12.3 27.5 8.8 14.9 60.7 19.7 25.2 11.4 12.7 85.9 70.9 11.6 50.6 38.7 31.5 26.1 19.1 12.2 9.3 29.2 24.7 18.8 42.6 25.6 18.8 10.3 35.1 7.1 11.5 30.2 21.2 28.0 22.0 16.1 50.1 10.7 31.2 19.7 64.0 37.9 111.3 46.7 46.2 49.7 56.3 46.8 46.7 42.8 63.6 51.8 49.4 90.7 44.5 69.9 82.5 55.6 43.4 10.7 11.4 11.4 14.4 10.4 10.6 11.1 10.8 11.1 11.5 10.9 12.7 47.6 9.6 21.7 9.1 71.4 169.9 81.2 65.2 52.9 6.0 33.7 46.6 5.5 25.8 32.2 9.2 6.2 45.3 62.8 27.9 11.7 22.6 32.7 49.5 38.0 33.2 37.7 35.7 10.0 22.7 69.4 46.9 15.8 42.0 21.5 15.7 30.0 21.9 30.4 0.0 12.7 43.4 42.7 28.8 65.4 11.9 59.7 37.7 40.9 6.5 23.5 10.4 43.3 9.0 18.4 20.5 34.4 37.2 37.5 76.5 24.2 16.9 64.8 5.3 32.9 68.4 44.6 47.8 37.1 46.4 152.3 61.6 60.4 13.5 35.5 72.1 EXT1 "LGCR, LGS, ttv" ENSG00000182197 "Exostosin glycosyltransferase 1" Q16394 8 117794490-118111826 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Cancer-related genes, Disease variant, Hereditary multiple exostoses, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 229.6;Inhibitory neurons: 421.4;Microglial cells: 144.3;Oligodendrocyte precursor cells: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 95.5;fHDF/TERT166: 82.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044394 Uncertain NA Yes 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA044394: AB_10963838" "unprognostic (1.29e-2)" "prognostic unfavorable (7.04e-4)" "unprognostic (2.73e-2)" "unprognostic (2.02e-3)" "unprognostic (2.19e-1)" "unprognostic (7.55e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.70e-1)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (6.58e-2)" "unprognostic (1.27e-2)" "unprognostic (9.84e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (1.85e-1)" 5.1 4.2 2.0 5.2 2.5 1.1 4.3 2.3 2.3 7.6 3.9 7.7 14.1 4.9 2.9 5.5 3.8 5.8 7.0 3.4 1.3 3.8 13.3 7.9 3.0 1.1 2.1 5.0 5.5 3.3 1.8 11.1 1.0 5.0 8.2 2.7 3.2 7.7 1.5 7.8 11.7 6.1 1.4 5.1 5.3 2.4 1.2 3.0 5.2 2.4 3.8 11.8 4.2 1.9 29.3 8.5 13.5 5.5 22.8 23.0 5.9 51.5 95.5 40.9 39.4 10.0 3.1 0.5 24.8 82.1 24.0 19.8 5.0 31.4 55.7 12.5 9.9 1.5 5.9 6.5 10.0 0.0 1.6 10.8 10.8 38.8 38.5 47.7 28.1 2.9 0.9 7.4 18.7 3.2 1.8 0.2 4.6 13.7 10.1 0.0 4.1 1.3 23.1 7.6 4.5 4.0 8.0 3.9 9.2 32.6 5.3 0.5 32.0 35.2 28.7 32.0 15.8 5.5 5.1 2.4 36.5 0.0 9.2 0.1 0.4 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.3 0.1 2.0 2.5 2.3 2.3 3.4 1.3 1.1 2.1 1.0 1.4 1.2 1.9 21.1 19.2 6.0 127.3 3.0 54.8 23.0 27.7 10.2 23.6 7.8 10.8 6.5 24.3 13.7 7.3 14.6 6.5 5.1 49.2 0.0 37.3 1.8 17.7 37.1 25.9 4.8 1.7 229.6 20.1 3.9 32.6 11.7 18.2 7.0 108.3 16.8 32.9 2.5 10.1 421.4 25.5 4.1 37.9 13.9 2.7 17.4 9.6 19.6 144.3 8.1 5.9 4.1 162.8 101.8 27.4 16.1 36.1 5.3 19.3 44.9 4.9 14.2 22.4 0.0 17.1 36.4 0.6 5.1 12.6 47.3 12.2 4.2 35.0 26.3 26.8 SAMD12 FLJ39458 ENSG00000177570 "Sterile alpha motif domain containing 12" Q8N8I0 8 118189455-118622112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Excitatory neurons: 537.6;Inhibitory neurons: 531.7;Oligodendrocytes: 1158.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 34.6;U-266/70: 14.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024634 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "HPA024634: AB_1856549" "unprognostic (6.96e-2)" "unprognostic (9.35e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.11e-4)" "unprognostic (4.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.99e-2)" "unprognostic (1.68e-1)" "unprognostic (3.94e-3)" "unprognostic (2.01e-1)" "prognostic favorable (1.52e-6)" "unprognostic (3.31e-2)" "unprognostic (1.76e-1)" "unprognostic (1.94e-1)" "unprognostic (6.35e-3)" 0.7 1.4 2.4 1.1 4.9 0.4 3.0 0.7 8.8 2.3 0.0 4.0 3.7 1.1 4.0 4.1 5.3 3.6 6.9 7.5 0.8 5.2 1.6 4.2 0.7 1.4 0.5 0.9 1.9 9.6 3.3 0.1 2.6 3.7 4.7 5.9 2.4 5.0 0.8 0.8 2.0 0.7 0.9 2.6 5.7 1.3 2.1 1.0 10.2 0.1 2.0 4.4 1.1 8.4 10.2 0.7 0.9 0.0 0.0 0.0 2.1 3.4 10.4 7.8 4.3 1.1 12.1 3.4 0.8 8.2 1.6 1.9 2.0 4.7 11.9 0.1 1.1 0.0 5.7 0.0 0.0 0.0 0.2 0.0 2.3 4.6 0.4 2.8 0.2 5.9 0.0 6.0 6.0 2.0 1.6 0.0 0.8 13.2 1.3 0.0 0.0 9.7 5.4 13.5 4.0 0.0 2.8 34.6 0.0 2.1 0.5 0.0 0.0 0.1 3.8 1.4 1.2 14.9 10.2 0.4 1.8 0.0 1.1 0.1 0.0 0.0 0.1 0.0 1.0 1.5 0.8 0.5 0.0 1.0 1.0 0.6 0.1 0.6 0.0 0.3 0.8 0.2 2.4 4.9 0.7 8.8 7.5 0.8 1.4 0.5 2.6 0.9 2.1 8.4 4.7 112.2 95.0 53.5 8.0 1.7 10.1 10.3 13.1 16.8 10.9 5.1 12.1 12.8 57.5 29.5 43.8 0.0 3.3 10.5 19.6 12.9 5.2 12.1 1.5 13.0 14.3 2.1 537.6 12.4 0.1 9.1 26.5 16.4 56.8 4.4 7.5 5.2 0.1 30.3 531.7 11.2 14.2 0.3 0.0 6.1 0.3 6.5 7.2 163.0 0.7 4.5 4.1 122.6 1158.0 13.0 3.5 0.4 16.9 5.0 8.6 17.4 68.0 26.9 0.0 0.5 0.9 0.5 2.4 15.9 1.7 0.0 8.9 4.5 11.9 13.6 TNFRSF11B "OCIF, OPG, TR1" ENSG00000164761 "TNF receptor superfamily member 11b" O00300 8 118923557-118951885 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Apoptosis Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 29.9;thyroid gland: 101.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 134.3;Collecting duct cells: 73.5;Ductal cells: 32.7;Proximal tubular cells: 117.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 40 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 40 "dendritic cells: 3.9" "Group enriched" "Detected in many" 4 "BJ: 546.7;BJ hTERT+: 2013.0" "Low region specificity" "Detected in all" CAB034939 Approved "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "CAB034939: " "unprognostic (1.39e-2)" "prognostic unfavorable (6.22e-4)" "unprognostic (5.27e-2)" "unprognostic (2.33e-2)" "unprognostic (4.27e-3)" "unprognostic (1.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.50e-2)" "unprognostic (9.94e-2)" "unprognostic (6.32e-2)" "unprognostic (3.53e-2)" "unprognostic (2.43e-1)" "prognostic favorable (6.79e-4)" "unprognostic (1.32e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (3.88e-4)" 3.3 3.3 2.6 5.3 3.1 0.0 2.6 2.6 4.1 1.1 3.5 2.5 1.4 10.2 0.5 0.4 1.4 5.8 9.4 2.5 2.7 29.9 14.2 9.4 7.0 5.0 3.0 0.3 1.8 0.5 1.8 4.9 3.3 1.6 3.5 0.3 1.4 1.0 0.4 0.5 2.2 2.6 3.1 2.6 1.2 0.1 3.0 1.3 101.8 0.8 2.9 10.7 0.3 3.8 0.0 0.9 8.6 0.0 27.5 5.3 0.0 546.7 2013.0 25.9 7.2 6.3 1.1 0.0 143.7 302.4 0.0 5.6 0.0 0.0 13.2 0.1 0.0 0.0 23.1 0.0 3.6 0.0 0.0 2.9 0.0 26.7 0.0 10.9 0.3 0.0 0.0 0.0 73.8 13.6 0.0 0.1 0.9 2.6 3.3 0.0 1.0 0.0 23.6 0.0 1.3 0.0 4.8 0.2 0.0 0.3 0.0 0.1 1.2 16.9 8.6 10.1 1.2 0.6 0.0 0.1 2.3 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 2.6 3.1 2.6 4.1 2.5 2.7 5.0 3.0 3.3 3.1 3.0 3.8 2.1 3.2 0.0 7.2 0.7 2.2 0.6 1.4 0.0 0.2 134.3 4.1 3.8 22.8 1.0 73.5 0.0 0.0 0.2 2.5 9.8 32.7 0.1 0.6 1.4 7.4 9.5 0.0 0.8 1.3 0.2 9.4 0.0 1.7 0.0 0.0 4.6 2.0 0.5 0.0 0.3 9.2 2.0 0.3 3.9 0.3 0.3 1.1 0.0 0.0 8.3 1.2 0.0 3.0 0.3 9.2 0.8 0.0 0.0 6.8 1.1 117.3 0.1 0.1 0.0 0.4 4.3 0.1 0.3 0.0 1.1 0.0 0.4 0.0 2.8 0.3 COLEC10 CL-L1 ENSG00000184374 "Collectin subfamily member 10" Q9Y6Z7 8 118995452-119108455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 65.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.9;Hepatic stellate cells: 10.4;Inhibitory neurons: 5.4;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 4.8" "Cancer enhanced" "Detected in some" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 3.4;SK-BR-3: 9.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Secreted to blood" NA NA 30000000 "Cluster 85: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (3.79e-4)" "unprognostic (6.25e-3)" "unprognostic (1.80e-3)" "unprognostic (7.73e-2)" "prognostic favorable (5.79e-4)" "unprognostic (1.05e-1)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.25e-2)" "unprognostic (9.02e-5)" "unprognostic (2.47e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-5)" "unprognostic (7.12e-2)" 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.7 0.6 0.1 0.4 0.4 65.7 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 10.9 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 6.9 0.0 0.2 1.0 0.0 0.0 0.0 0.0 10.4 0.4 0.3 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.8 0.1 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 MAL2 ENSG00000147676 "Mal, T cell differentiation protein 2" Q969L2 8 119165034-119245673 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 259.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 389.9;Distal enterocytes: 433.3;Pancreatic endocrine cells: 329.8;Suprabasal keratinocytes: 455.8;Urothelial cells: 594.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1042.5;HaCaT: 451.8;OE19: 1132.4;RPTEC TERT1: 385.4;SK-BR-3: 1439.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043831 Uncertain NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "HPA043831: " "prognostic unfavorable (4.57e-6)" "unprognostic (3.12e-1)" "unprognostic (4.04e-1)" "prognostic unfavorable (8.44e-5)" "unprognostic (2.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-2)" "unprognostic (7.20e-2)" "unprognostic (5.86e-2)" "unprognostic (2.00e-3)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.09e-1)" "prognostic favorable (2.39e-5)" "unprognostic (5.48e-2)" "unprognostic (1.34e-1)" "unprognostic (3.33e-1)" "unprognostic (9.27e-3)" 14.1 1.8 8.5 10.6 13.4 0.0 65.6 15.3 28.0 41.9 0.0 102.9 64.3 6.7 14.2 259.2 54.4 33.1 2.1 22.2 17.0 85.7 47.0 81.6 1.3 0.0 4.2 0.5 37.4 43.5 35.8 12.0 0.0 26.9 94.2 2.6 62.6 41.2 0.4 121.0 53.0 2.6 0.0 0.4 137.6 12.5 8.3 4.3 147.5 0.1 56.0 69.0 102.6 3.4 1042.5 0.0 1.0 0.3 0.2 0.0 92.9 0.1 2.3 1.2 1.6 87.7 329.0 0.3 56.2 0.0 0.4 451.8 0.8 32.9 0.5 0.9 2.6 0.0 13.8 86.1 0.3 0.6 0.3 0.0 225.5 0.0 34.3 1.7 0.3 0.0 0.2 0.5 0.0 244.9 0.8 0.3 8.2 1132.4 309.2 0.6 0.0 0.7 385.4 257.4 56.7 0.3 17.8 1439.4 2.7 6.8 191.4 3.0 0.0 0.6 3.1 1.3 1.9 5.5 0.8 1.0 0.4 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 13.4 15.3 28.0 22.2 17.0 0.0 4.2 0.0 0.0 8.3 3.4 0.5 112.2 130.8 4.2 2.7 114.7 79.9 59.3 19.9 1.5 118.9 50.7 1.6 90.1 119.7 389.9 0.0 25.0 0.4 433.3 109.5 206.0 0.5 71.8 10.3 3.7 41.9 0.0 62.4 178.6 23.5 4.7 149.9 139.4 14.7 0.0 3.6 44.9 2.9 5.0 9.8 145.9 71.2 0.3 14.3 2.2 0.6 2.3 16.0 3.7 3.6 1.0 0.0 3.5 3.6 329.8 252.9 0.0 1.2 285.4 70.2 19.9 107.5 1.0 0.0 0.0 7.0 1.9 9.7 268.8 455.8 9.3 2.8 0.0 122.5 594.5 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ENPP2 "ATX, PD-IALPHA, PDNP2" ENSG00000136960 "Ectonucleotide pyrophosphatase/phosphodiesterase 2" Q13822 8 119557086-119673453 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Chemotaxis, Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 383.3;choroid plexus: 753.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1041.6" "Cancer enhanced" "Detected in all" "renal cancer: 46.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 53.8" "Lineage enriched" "Detected in many" 8 "granulocytes: 53.8" "Cell line enhanced" "Detected in many" "AF22: 111.4;ASC diff: 147.7;ASC TERT1: 312.5;BJ: 103.2;BJ hTERT+: 188.9;fHDF/TERT166: 124.2;HSkMC: 144.7;U-2197: 108.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023700, HPA053652" Approved Approved "Nucleoplasm,Golgi apparatus,Actin filaments" "Secreted to blood" NA NA 1200000000 "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Golgi apparatus" "Actin filaments" "HPA023700: AB_1848170, HPA053652: AB_2682218" "unprognostic (1.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.63e-2)" "unprognostic (3.93e-2)" "unprognostic (1.23e-1)" "unprognostic (1.37e-1)" "unprognostic (9.70e-3)" "unprognostic (7.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "prognostic favorable (2.07e-5)" "unprognostic (5.54e-2)" "unprognostic (3.14e-1)" "unprognostic (2.37e-1)" "unprognostic (5.18e-2)" "unprognostic (2.37e-2)" "unprognostic (1.50e-1)" 104.7 46.7 98.9 62.0 208.4 2.7 89.7 188.1 150.1 73.6 753.4 32.6 67.5 139.2 20.2 9.0 55.7 39.9 9.9 111.0 133.0 76.6 28.5 42.7 109.8 246.2 164.4 15.2 15.9 20.2 11.8 252.3 244.4 26.4 32.3 6.9 9.9 27.3 8.9 17.5 45.8 85.1 147.8 51.4 26.9 31.3 153.7 20.8 10.8 23.9 85.8 45.1 18.1 383.3 0.0 0.0 111.4 0.0 147.7 312.5 0.4 103.2 188.9 43.9 42.1 0.0 0.0 0.1 1.3 124.2 0.1 0.3 2.3 0.0 31.3 8.7 3.4 0.0 0.2 3.1 67.0 0.0 0.5 144.7 1.3 89.3 4.3 0.6 0.5 0.1 0.1 18.1 2.5 0.0 0.1 0.7 4.4 0.0 0.5 0.1 0.1 0.6 0.3 0.0 1.1 2.2 0.1 0.4 0.2 4.2 0.1 0.0 0.0 89.6 1.9 108.6 0.9 0.9 0.0 0.0 75.0 0.8 2.4 53.8 0.2 9.5 0.0 0.1 0.1 0.4 0.5 0.0 1.0 0.1 3.0 1.1 0.5 0.4 0.2 6.8 0.0 0.6 98.9 208.4 188.1 150.1 111.0 133.0 246.2 164.4 244.4 147.8 153.7 383.3 231.4 12.8 3.6 2.0 1.8 10.6 0.5 0.0 19.9 1.9 2.1 2.8 1.8 35.8 0.6 1.8 0.0 5.2 4.9 0.3 1.9 0.1 83.9 12.7 8.8 79.9 54.0 0.8 2.5 0.0 2.2 76.9 3.6 1.4 6.3 0.4 31.1 0.8 65.8 0.0 4.2 3.3 0.0 18.6 14.9 9.5 3.1 16.2 46.2 6.5 0.1 6.4 0.0 16.6 1041.6 0.7 2.6 3.4 1.9 0.1 4.2 47.6 3.7 1.2 0.0 3.1 9.6 1.7 0.4 7.8 5.3 6.4 1.7 1.1 2.8 1.4 TAF2 "CIF150, TAF2B, TAFII150" ENSG00000064313 "TATA-box binding protein associated factor 2" Q6P1X5 8 119730774-119832841 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 59: Non-specific - Transcription" "unprognostic (1.69e-2)" "unprognostic (9.33e-3)" "unprognostic (3.79e-2)" "prognostic unfavorable (2.45e-4)" "unprognostic (8.12e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.44e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-3)" "unprognostic (1.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.16e-2)" "unprognostic (2.47e-2)" 9.2 10.9 4.2 11.2 5.6 14.6 10.6 12.2 6.4 10.3 6.4 9.1 8.8 12.6 11.0 9.5 8.6 9.8 7.1 4.4 6.2 10.6 12.1 7.9 14.2 4.9 4.8 11.2 8.2 11.7 6.5 13.1 5.4 9.4 10.4 10.0 7.7 9.7 7.0 10.8 8.6 11.3 5.0 11.3 9.9 13.7 4.9 15.8 10.6 8.5 14.8 12.5 8.4 7.2 41.3 24.0 27.1 25.1 22.3 24.1 16.9 31.9 26.3 34.7 43.6 15.3 22.9 46.4 27.5 29.1 19.5 26.2 42.1 19.3 49.3 53.2 25.4 58.0 21.7 17.1 35.3 27.9 33.8 22.6 16.9 34.3 39.9 19.0 34.6 24.0 44.4 25.3 32.8 23.2 52.9 12.0 20.4 29.6 27.2 30.6 22.4 25.2 20.7 29.7 35.9 21.1 28.5 88.3 22.6 23.5 26.3 20.7 27.0 23.6 39.1 22.7 46.3 43.2 55.3 57.5 29.0 36.5 22.8 12.5 4.2 7.4 6.0 5.5 5.4 4.7 6.2 6.2 5.5 4.1 5.6 5.8 2.6 6.5 8.1 3.3 7.8 4.4 4.2 5.6 12.2 6.4 4.4 6.2 4.9 4.8 5.4 5.0 4.9 7.2 19.6 12.8 18.8 41.4 23.5 18.7 18.7 14.2 23.3 15.8 15.8 11.7 12.3 11.5 16.7 22.0 20.9 18.1 18.0 10.2 3.9 10.1 2.6 16.7 27.9 19.0 9.6 15.8 56.0 10.7 12.8 18.5 21.4 26.4 21.5 18.2 13.2 17.9 12.5 8.4 52.7 12.8 10.2 14.7 12.9 3.9 15.5 15.8 8.8 37.5 11.7 7.7 21.6 53.3 59.0 11.5 9.8 18.0 23.6 18.2 9.0 15.7 22.3 14.9 13.1 21.3 17.4 34.8 35.5 27.8 20.6 21.1 21.0 17.8 12.0 19.7 DSCC1 "DCC1, hDCC1, MGC5528" ENSG00000136982 "DNA replication and sister chromatid cohesion 1" Q9BVC3 8 119833976-119855894 "Predicted intracellular proteins" "Cell cycle, DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 24.6;Extravillous trophoblasts: 17.6;Spermatogonia: 18.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023780, HPA024401" Uncertain Approved Nucleoplasm NA Yes "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "HPA023780: AB_2671311, HPA024401: AB_2671557" "unprognostic (7.36e-3)" "unprognostic (8.24e-2)" "unprognostic (1.56e-1)" "unprognostic (4.71e-3)" "unprognostic (9.91e-2)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.92e-6)" "prognostic unfavorable (3.93e-4)" "prognostic unfavorable (5.73e-4)" "unprognostic (3.24e-3)" "unprognostic (8.12e-3)" "unprognostic (2.72e-2)" "unprognostic (2.32e-9)" "unprognostic (2.75e-2)" "unprognostic (5.01e-1)" "unprognostic (4.40e-2)" "unprognostic (8.18e-2)" 1.8 1.8 1.3 3.7 1.6 6.1 2.4 2.1 2.0 2.6 1.1 2.7 2.4 2.4 1.3 2.4 1.5 1.0 1.5 1.4 1.4 0.9 1.1 1.4 7.1 1.5 1.5 1.5 2.8 0.5 0.5 2.3 1.6 1.9 3.5 0.3 3.7 1.2 2.1 2.6 2.3 2.7 1.5 1.3 1.7 2.6 1.4 9.9 1.0 3.4 5.7 1.5 2.1 1.8 34.3 16.6 32.1 29.4 4.6 8.3 13.8 23.1 4.7 16.3 16.9 15.2 20.4 61.7 19.7 6.9 10.1 24.8 36.7 14.4 17.5 42.2 33.3 78.7 16.2 17.9 1.5 31.2 26.4 3.8 2.2 20.1 9.7 3.8 4.7 40.5 27.2 26.9 19.9 33.8 82.4 19.2 47.2 90.4 41.2 29.1 30.4 29.9 12.7 21.3 28.7 17.6 12.4 96.7 15.8 25.0 18.1 17.0 3.2 17.7 48.0 17.2 33.9 36.5 58.2 65.4 9.0 49.2 26.2 0.0 0.0 0.0 0.9 0.0 0.7 0.3 0.2 0.4 0.0 0.1 0.1 0.3 0.0 0.8 0.0 0.2 0.3 0.2 1.3 1.6 2.1 2.0 1.4 1.4 1.5 1.5 1.6 1.5 1.4 1.8 4.7 0.0 0.5 2.6 1.2 3.4 2.2 2.1 4.6 0.7 2.2 3.2 0.8 1.5 0.2 0.0 0.0 7.9 1.6 1.0 0.0 1.6 0.1 0.8 2.8 3.0 0.0 24.6 6.4 2.4 17.6 4.3 1.5 1.3 4.5 3.7 4.6 0.9 4.7 0.0 5.2 1.2 2.0 1.0 1.2 0.2 1.2 0.9 3.6 1.0 0.0 1.5 1.0 7.5 5.3 0.5 0.3 2.6 5.2 1.7 0.2 1.5 1.7 0.3 0.0 2.3 3.3 1.1 18.8 6.0 3.3 1.4 3.0 2.0 3.8 1.5 DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 158.2;tongue: 122.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 86.1;Glandular and luminal cells: 66.1;Oligodendrocytes: 123.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cell line enhanced" "Detected in many" "Daudi: 105.1;RPMI-8226: 193.2;RPTEC TERT1: 149.3;U-698: 55.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: AB_1847606, HPA023945: AB_1847607, HPA024011: AB_1847608" "unprognostic (3.41e-1)" "unprognostic (1.95e-1)" "unprognostic (1.53e-2)" "unprognostic (1.15e-2)" "unprognostic (3.19e-1)" "unprognostic (2.57e-1)" "unprognostic (1.08e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-1)" "unprognostic (2.49e-2)" "unprognostic (3.24e-2)" "unprognostic (6.02e-2)" "unprognostic (7.29e-2)" "unprognostic (5.66e-2)" "unprognostic (1.02e-1)" "unprognostic (4.16e-2)" "unprognostic (2.84e-2)" 14.4 52.8 12.0 3.0 16.7 2.0 20.7 12.6 11.9 39.2 3.8 23.3 16.9 16.5 11.1 15.2 27.1 10.8 5.1 9.7 23.2 40.0 16.3 5.3 10.1 15.8 12.5 24.7 11.9 16.9 11.4 4.9 15.3 12.1 9.9 2.0 106.3 15.6 158.2 6.6 14.5 15.5 14.8 9.5 40.0 2.9 16.3 5.1 98.0 122.3 2.9 5.6 7.0 24.2 0.1 3.5 0.3 1.1 21.0 6.2 0.3 0.1 0.3 0.6 0.5 2.4 0.4 105.1 2.3 1.2 0.3 0.3 5.4 0.2 0.4 2.3 2.7 14.2 0.9 0.6 12.8 3.0 23.7 5.5 9.5 0.8 0.6 0.1 0.0 1.8 0.1 16.9 0.3 7.1 0.1 2.5 1.3 45.5 3.7 0.4 4.9 193.2 149.3 4.1 3.2 0.7 1.7 11.0 3.2 2.8 9.6 0.5 0.0 0.4 0.9 21.4 0.5 45.4 11.4 55.2 6.5 3.9 0.6 0.0 0.9 0.0 0.2 1.7 0.8 0.1 0.4 0.7 20.3 0.1 0.8 0.6 0.3 0.4 0.2 1.0 0.4 1.0 12.0 16.7 12.6 11.9 9.7 23.2 15.8 12.5 15.3 14.8 16.3 24.2 23.1 6.4 9.3 4.9 2.9 5.2 15.4 3.8 27.3 2.1 16.5 10.4 2.4 15.7 8.4 25.8 0.0 0.6 0.8 2.7 86.1 5.7 2.2 19.0 9.7 7.5 16.7 12.4 14.5 11.8 4.1 10.0 29.6 66.1 12.0 5.4 2.5 12.7 3.3 0.0 31.0 7.7 0.0 16.0 39.5 2.2 11.8 14.9 14.2 46.9 1.5 1.2 2.1 9.5 123.9 1.1 36.5 3.4 6.4 7.1 21.0 33.6 1.1 0.7 0.0 8.1 5.7 3.6 3.8 16.5 5.5 0.4 1.3 6.0 16.5 21.9 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 MRPL13 "L13, L13A, L13mt, RPL13, RPML13" ENSG00000172172 "Mitochondrial ribosomal protein L13" Q9BYD1 8 120380761-120445402 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 264.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 497.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060899 Approved NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA060899: AB_2684382" "prognostic unfavorable (1.37e-4)" "unprognostic (4.91e-2)" "unprognostic (8.50e-2)" "unprognostic (3.61e-2)" "unprognostic (1.81e-1)" "unprognostic (1.66e-1)" "unprognostic (7.28e-3)" "unprognostic (1.34e-3)" "unprognostic (1.18e-1)" "unprognostic (1.56e-2)" "unprognostic (1.63e-3)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (7.48e-2)" "unprognostic (2.32e-1)" "unprognostic (1.45e-1)" "unprognostic (1.84e-1)" 21.3 37.8 18.2 19.1 18.5 22.1 26.6 19.5 27.3 17.0 20.0 37.6 24.4 16.3 24.2 35.6 16.2 15.8 38.2 17.7 20.3 45.6 51.1 16.4 24.8 18.9 19.0 13.1 18.1 33.5 15.2 20.9 19.1 18.2 36.5 21.4 22.0 14.6 33.8 17.7 22.5 19.3 20.1 18.3 24.2 15.1 19.2 28.2 18.2 47.2 25.0 24.7 21.8 20.4 106.5 53.8 62.8 52.7 43.0 62.7 51.2 58.3 57.1 81.3 88.5 56.6 80.2 78.8 85.4 49.4 54.6 56.5 82.1 74.9 114.2 107.4 84.2 99.6 39.0 81.8 51.8 62.7 47.1 48.7 123.2 68.6 71.8 46.4 67.2 78.7 103.8 56.5 73.4 59.7 101.8 60.9 60.5 194.0 122.7 52.9 61.1 107.7 90.7 57.1 74.0 38.1 41.0 497.7 78.4 55.1 96.0 65.9 39.3 42.0 87.1 53.3 107.7 45.2 98.9 110.7 77.8 112.6 76.3 48.4 59.7 66.0 47.6 92.2 56.1 58.9 57.4 62.4 89.8 46.8 55.1 56.4 10.4 68.3 103.1 72.4 77.2 92.2 18.2 18.5 19.5 27.3 17.7 20.3 18.9 19.0 19.1 20.1 19.2 20.4 48.4 70.5 41.9 5.5 37.2 33.6 55.9 235.1 46.7 18.3 37.8 52.1 119.6 44.3 117.8 55.2 20.9 134.2 33.2 56.4 262.2 121.0 10.4 68.4 53.1 45.6 45.0 54.5 14.7 100.7 171.0 49.1 30.5 51.4 36.8 39.3 35.0 78.1 103.3 16.8 14.1 93.3 177.0 33.6 31.4 9.4 38.2 47.5 32.0 9.4 80.1 49.9 32.0 10.1 14.3 95.1 84.9 35.3 42.3 46.5 81.9 264.8 140.7 25.6 39.5 29.0 66.4 103.2 64.8 65.3 45.3 115.9 39.9 114.0 100.8 70.2 MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Excitatory neurons: 14.7;Oligodendrocytes: 16.1;Spermatocytes: 16.2;Spermatogonia: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 22: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Nuclear bodies" "HPA025694: AB_1854169, HPA050594: AB_2681185" "unprognostic (1.92e-2)" "unprognostic (1.07e-1)" "unprognostic (4.47e-1)" "unprognostic (3.53e-4)" "unprognostic (1.20e-1)" "unprognostic (5.40e-3)" "unprognostic (2.77e-6)" "unprognostic (3.99e-3)" "unprognostic (1.50e-2)" "unprognostic (7.86e-3)" "unprognostic (3.38e-3)" "unprognostic (3.29e-1)" "unprognostic (5.20e-10)" "unprognostic (3.41e-3)" "unprognostic (2.51e-1)" "unprognostic (3.02e-2)" "unprognostic (5.86e-2)" 1.3 1.1 1.0 2.5 1.2 4.0 2.6 3.6 1.7 1.6 0.7 1.7 1.5 2.1 2.4 1.4 1.7 1.2 0.6 1.0 0.9 1.0 0.8 1.3 4.3 1.0 1.0 2.4 0.9 1.0 0.8 2.1 1.2 1.5 2.6 4.3 1.1 1.0 0.7 3.0 1.3 2.0 0.9 1.8 1.1 5.0 1.1 4.6 0.8 0.8 4.0 1.0 1.3 1.4 15.3 4.5 14.6 6.0 2.1 3.5 7.1 11.4 6.5 16.4 21.0 4.9 8.3 13.8 11.2 3.8 4.9 13.0 13.9 6.8 20.3 11.5 10.6 11.6 6.7 5.6 1.1 12.4 8.6 1.3 2.9 12.7 8.1 2.5 7.3 12.6 7.6 10.2 9.7 6.9 19.8 7.6 6.5 12.0 9.0 11.3 15.0 9.8 3.9 5.3 7.4 8.6 7.7 44.8 7.0 7.9 8.5 8.9 4.5 7.0 12.7 9.0 18.6 3.9 8.9 8.0 6.6 15.1 8.3 0.0 0.1 0.1 0.3 0.6 0.5 0.7 0.5 0.7 0.2 0.5 0.8 0.7 0.0 0.5 0.3 0.0 0.7 0.3 1.0 1.2 3.6 1.7 1.0 0.9 1.0 1.0 1.2 0.9 1.1 1.4 1.6 0.0 1.5 7.5 2.9 0.8 1.7 1.5 1.8 0.0 1.4 1.3 1.1 0.0 1.1 1.8 0.0 2.3 2.5 0.5 0.0 0.9 0.8 1.3 2.6 1.1 0.0 12.8 14.7 1.8 3.0 2.5 2.6 1.5 2.5 5.0 1.8 0.9 1.6 0.0 9.1 0.9 0.0 0.3 1.8 0.4 1.5 1.7 1.8 3.7 1.0 0.0 2.1 9.0 16.1 0.6 0.1 1.2 2.3 1.2 0.3 0.3 2.4 0.0 0.0 5.6 2.6 16.2 10.2 1.4 0.6 0.7 3.3 1.5 0.8 0.8 SNTB1 "59-DAP, A1B, BSYN2, SNT2, SNT2B1, TIP-43" ENSG00000172164 "Syntrophin beta 1" Q13884 8 120535745-120813273 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 89.3" "Cell type enhanced" "Detected in many" "Astrocytes: 70.2;Hepatocytes: 66.8;Microglial cells: 45.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 84.9;OE19: 78.5;U-266/70: 77.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA024659 Uncertain "Intracellular and membrane" NA NA 25000 "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" "HPA024659: AB_1857713" "unprognostic (1.32e-1)" "unprognostic (2.77e-2)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.24e-2)" "unprognostic (1.74e-1)" "unprognostic (1.76e-2)" "unprognostic (6.41e-3)" "unprognostic (2.07e-1)" "unprognostic (3.88e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-1)" "unprognostic (2.00e-2)" "unprognostic (5.08e-2)" "unprognostic (5.88e-2)" "unprognostic (1.03e-1)" "unprognostic (1.71e-1)" 7.9 66.4 7.5 5.5 6.5 18.9 8.0 5.8 5.9 5.6 42.9 6.2 5.7 4.4 2.7 8.4 6.0 4.3 4.9 6.1 11.8 12.6 89.3 15.4 7.3 7.2 11.4 2.5 45.0 1.4 2.6 8.6 7.8 4.8 6.4 4.8 34.8 3.4 28.2 9.8 6.3 3.1 6.0 11.9 24.1 9.8 9.1 3.4 61.4 32.4 3.5 3.9 3.6 6.5 0.1 1.8 0.7 0.0 11.3 22.9 0.1 6.0 36.7 1.8 2.7 12.0 1.6 0.0 10.7 6.8 0.0 0.1 2.0 0.0 1.3 5.6 6.5 0.0 0.3 84.9 1.2 16.9 0.0 11.4 0.0 10.1 0.0 14.9 0.4 10.4 0.0 32.3 5.9 3.3 0.0 13.7 2.1 78.5 8.7 0.0 43.8 0.1 34.4 2.0 0.1 0.4 2.4 12.5 30.2 0.7 1.5 30.5 0.0 23.7 1.4 0.0 2.0 77.2 33.0 34.8 18.4 49.0 26.7 1.8 0.8 2.7 2.2 0.4 0.5 0.5 0.4 1.1 0.6 0.2 1.1 1.1 0.1 1.6 0.3 0.0 0.0 0.6 7.5 6.5 5.8 5.9 6.1 11.8 7.2 11.4 7.8 6.0 9.1 6.5 1.9 12.8 27.2 70.2 4.7 0.4 0.7 0.9 1.8 2.4 8.5 6.0 2.0 2.8 9.0 5.5 2.1 0.8 8.4 1.3 9.8 1.5 9.3 2.4 5.8 4.2 0.0 14.1 2.4 10.9 2.2 9.8 11.2 6.2 1.3 8.8 13.2 66.8 11.3 0.0 3.1 3.9 16.2 29.9 4.3 4.2 4.7 18.1 1.8 45.9 12.1 16.0 18.6 2.5 12.2 4.3 1.9 13.2 2.8 1.1 0.1 3.3 13.8 0.7 13.1 3.9 14.3 1.1 0.2 10.1 1.0 0.3 12.0 11.0 4.1 0.6 HAS2 ENSG00000170961 "Hyaluronan synthase 2" Q92819 8 121612116-121641440 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.7;urinary bladder: 20.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 54.1;Fibroblasts: 62.1;Langerhans cells: 28.9;Melanocytes: 30.2;Smooth muscle cells: 30.7;Urothelial cells: 89.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HBF TERT88: 157.8;hTEC/SVTERT24-B: 153.8;LHCN-M2: 206.5;U-138 MG: 396.9;U-251 MG: 123.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA052060 Approved "Nuclear speckles" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nuclear speckles" "HPA052060: AB_2681712" "unprognostic (7.01e-2)" "unprognostic (1.34e-2)" "unprognostic (4.07e-2)" "unprognostic (4.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.57e-3)" "unprognostic (3.44e-2)" "unprognostic (1.34e-1)" "unprognostic (8.19e-3)" "unprognostic (1.24e-1)" "unprognostic (1.66e-7)" "unprognostic (1.47e-3)" "unprognostic (3.67e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-3)" 22.7 0.3 0.6 9.0 0.5 0.1 5.3 0.6 0.5 0.7 0.1 4.1 2.8 0.8 1.2 1.6 1.7 7.8 4.0 0.5 1.5 1.1 2.9 3.7 1.6 1.6 2.1 0.2 0.9 0.2 0.3 2.3 1.3 1.1 5.6 0.0 1.0 0.2 0.5 2.3 5.2 3.9 1.1 0.1 2.0 1.8 1.3 0.8 0.7 0.9 0.9 20.5 0.6 0.9 0.3 2.8 0.0 0.4 4.7 11.8 0.0 23.5 17.3 29.9 51.2 0.2 0.4 0.1 0.0 20.8 0.0 4.2 0.0 0.0 157.8 0.1 0.6 0.0 0.6 0.0 19.9 0.0 0.0 31.0 0.0 153.8 14.1 0.7 0.0 0.0 0.0 0.0 206.5 0.3 0.0 0.0 0.4 0.0 3.4 0.0 26.6 0.0 0.0 2.0 0.0 0.4 10.0 0.0 5.6 9.0 0.2 0.3 0.0 396.9 1.4 37.7 123.7 0.0 0.0 0.0 8.5 0.1 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 0.6 0.5 0.5 1.5 1.6 2.1 1.3 1.1 1.3 0.9 2.2 0.0 0.0 0.0 0.0 16.3 54.1 1.8 0.6 0.0 0.1 0.4 1.2 0.0 0.2 3.7 0.0 0.2 0.2 1.6 0.0 0.9 19.0 0.1 3.5 7.2 1.2 0.0 0.1 0.0 0.0 62.1 1.1 0.1 13.4 0.0 0.7 0.0 0.3 0.0 0.2 2.3 0.0 0.0 28.9 3.4 1.8 0.7 30.2 0.0 0.0 0.0 0.0 16.1 0.2 1.6 1.9 0.0 0.0 11.0 0.0 0.1 0.0 0.0 0.0 6.9 30.7 0.3 0.1 0.6 11.9 0.1 1.5 0.0 3.9 89.3 ZHX2 KIAA0854 ENSG00000178764 "Zinc fingers and homeoboxes 2" Q9Y6X8 8 122781655-122974510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Astrocytes: 252.1;Microglial cells: 81.5;Oligodendrocyte precursor cells: 200.6;Oligodendrocytes: 176.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 49.3;REH: 53.1;U-698: 48.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006769, HPA006996" Enhanced Enhanced Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "HPA006769: AB_10669919, HPA006996: AB_10670555" "unprognostic (8.28e-2)" "unprognostic (3.80e-3)" "unprognostic (6.48e-2)" "unprognostic (6.90e-2)" "unprognostic (8.19e-3)" "unprognostic (3.61e-2)" "unprognostic (2.03e-2)" "unprognostic (2.68e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (2.25e-1)" "unprognostic (1.36e-1)" "unprognostic (7.29e-2)" "unprognostic (2.03e-2)" "unprognostic (1.70e-1)" "unprognostic (7.61e-3)" "unprognostic (3.04e-1)" 11.6 11.7 18.5 14.0 25.7 6.8 11.5 19.4 19.5 15.2 10.0 8.8 5.4 14.7 7.0 9.7 15.1 12.3 20.6 18.7 18.6 10.2 15.0 13.8 27.6 23.0 21.4 27.6 17.7 7.7 12.0 6.4 21.8 15.1 6.5 11.7 13.3 9.7 33.8 9.3 12.0 11.5 19.2 15.8 7.9 2.8 21.8 14.2 13.7 21.9 23.2 13.0 10.7 31.3 5.7 2.7 14.9 3.0 7.1 2.2 0.0 3.2 9.9 3.5 4.6 0.6 18.0 49.3 13.0 10.7 2.7 4.7 10.1 6.3 3.8 22.8 7.0 22.3 3.3 17.5 7.9 5.5 7.0 6.4 7.4 3.3 17.2 16.6 4.2 8.9 0.8 16.7 4.2 16.2 5.2 5.1 8.7 2.9 3.7 53.1 8.1 4.1 17.2 13.5 6.6 3.7 12.9 38.8 6.8 9.9 6.6 12.6 6.9 2.8 7.3 3.4 7.0 4.5 0.1 48.4 2.8 4.3 4.7 13.0 1.0 5.5 6.5 1.3 6.8 11.6 4.7 6.3 1.2 10.0 6.8 5.7 5.2 7.0 2.1 5.4 5.2 3.5 18.5 25.7 19.4 19.5 18.7 18.6 23.0 21.4 21.8 19.2 21.8 31.3 6.0 6.4 4.6 252.1 24.8 5.5 5.1 3.4 8.6 1.8 12.0 6.2 11.2 12.8 2.7 9.2 0.0 0.5 19.5 3.5 3.9 10.7 7.7 4.2 9.1 7.1 4.2 1.7 4.4 6.2 0.4 15.4 5.6 11.8 8.2 3.0 5.7 11.5 1.9 5.0 23.5 5.0 8.2 5.5 18.0 2.6 10.5 5.5 10.6 81.5 4.1 12.6 8.2 200.6 176.9 6.2 3.9 19.5 16.6 13.0 4.9 5.2 2.8 0.8 0.0 21.4 9.8 0.6 0.1 8.3 8.8 1.4 16.1 4.2 4.0 10.2 DERL1 "DER-1, DER1, derlin-1, FLJ13784, MGC3067, PRO2577" ENSG00000136986 "Derlin 1" Q9BUN8 8 123013170-123042302 "Plasma proteins, Predicted membrane proteins, Transporters" "Host-virus interaction, Protein transport, Transport, Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 225.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 825.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016562, CAB037269" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum" "CAB037269: AB_609868, HPA016562: AB_1847611" "prognostic unfavorable (2.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (5.66e-5)" "unprognostic (9.48e-2)" "unprognostic (4.21e-3)" "unprognostic (2.76e-1)" "unprognostic (1.28e-3)" "unprognostic (4.42e-2)" "unprognostic (5.38e-2)" "unprognostic (1.41e-3)" "unprognostic (4.35e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.88e-3)" "unprognostic (2.51e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" 69.1 47.6 15.2 53.7 16.4 104.1 34.1 20.2 18.2 26.6 26.6 50.0 47.9 29.4 31.4 35.4 29.4 32.9 41.3 17.9 18.3 30.8 77.5 37.1 48.7 15.7 16.4 38.1 31.6 26.9 23.0 28.0 15.7 27.0 42.8 29.6 29.6 28.7 73.3 23.6 47.0 34.4 16.7 40.0 38.5 32.1 18.0 27.2 42.4 49.1 55.5 41.8 22.5 19.5 130.8 93.9 55.7 72.6 98.3 72.8 47.1 108.9 72.1 68.7 85.1 59.7 126.9 150.7 129.8 87.4 81.2 107.0 51.8 69.3 97.4 174.9 57.6 157.2 62.9 51.6 89.2 62.2 111.0 66.9 87.8 76.0 89.8 62.5 62.8 60.6 95.9 193.7 78.7 254.8 68.5 39.4 42.1 166.4 82.5 68.3 46.2 252.1 182.2 92.1 60.5 89.8 109.9 825.1 68.6 59.6 97.3 55.4 74.2 82.2 154.1 74.1 102.1 239.5 444.6 136.5 135.4 76.4 79.4 73.1 60.7 72.6 89.3 75.7 93.0 69.8 59.5 74.0 49.5 56.1 41.0 64.0 42.1 77.8 77.9 56.6 80.0 83.3 15.2 16.4 20.2 18.2 17.9 18.3 15.7 16.4 15.7 16.7 18.0 19.5 38.6 32.1 25.9 12.4 78.3 42.3 41.8 57.3 26.7 22.6 38.3 21.3 28.1 17.2 44.8 29.5 20.9 41.0 67.6 43.3 9.8 87.7 85.5 18.9 32.3 39.2 30.5 41.0 11.5 75.4 71.4 43.8 26.5 31.2 42.6 24.0 39.3 75.9 68.0 18.5 12.8 62.2 42.7 49.4 44.2 19.9 24.5 45.6 60.5 14.0 47.6 25.5 59.8 17.6 19.1 68.4 40.6 25.6 225.0 63.7 56.6 28.0 31.3 25.6 46.0 32.7 77.6 75.4 40.3 41.0 50.7 78.0 69.8 34.8 37.5 64.4 TBC1D31 "Gm85, MGC21654, WDR67" ENSG00000156787 "TBC1 domain family member 31" Q96DN5 8 123041968-123152153 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.6" "Cell type enhanced" "Detected in many" "Astrocytes: 19.9;Excitatory neurons: 23.4;Inhibitory neurons: 32.0;NK-cells: 24.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 83.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023710 Approved Approved Centrosome NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Centrosome "HPA023710: AB_1858819" "unprognostic (1.39e-1)" "unprognostic (5.44e-3)" "unprognostic (7.21e-2)" "unprognostic (3.18e-5)" "unprognostic (2.42e-1)" "unprognostic (8.98e-2)" "unprognostic (2.63e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (1.53e-2)" "unprognostic (6.59e-2)" "unprognostic (8.88e-2)" "unprognostic (1.13e-1)" "unprognostic (1.18e-4)" "unprognostic (1.78e-3)" "unprognostic (1.57e-1)" "unprognostic (1.76e-2)" "unprognostic (2.33e-1)" 3.9 2.5 5.8 6.0 7.8 7.4 2.0 20.6 6.6 1.7 5.2 4.2 5.4 2.4 1.4 2.5 4.2 2.2 2.7 7.3 4.1 2.8 3.1 2.5 7.2 4.3 5.5 1.7 3.8 2.9 3.5 1.9 5.1 2.3 3.5 4.9 2.4 1.7 4.4 2.9 4.8 2.7 4.4 5.8 3.4 5.1 6.0 14.4 3.1 2.5 6.1 2.2 1.7 7.3 30.6 19.5 15.4 12.9 5.1 5.5 10.9 17.5 6.4 14.0 12.7 17.9 11.4 11.2 21.5 4.7 9.5 21.1 14.3 7.2 19.7 31.3 31.6 28.8 13.5 8.3 7.7 11.9 20.3 4.4 4.2 11.6 11.9 4.1 10.2 31.0 24.0 23.1 10.2 50.5 37.2 8.1 12.8 26.5 29.8 21.2 14.5 16.8 9.4 11.1 16.8 14.7 31.5 83.2 9.7 9.8 15.8 9.2 8.8 12.8 31.9 11.9 22.1 34.5 58.1 15.1 13.2 20.1 19.0 9.1 10.0 10.6 17.4 12.6 26.6 9.2 10.6 14.3 8.8 8.4 10.8 12.3 5.8 20.5 11.2 7.9 11.6 15.6 5.8 7.8 20.6 6.6 7.3 4.1 4.3 5.5 5.1 4.4 6.0 7.3 2.7 0.0 3.4 19.9 3.7 0.5 1.0 2.4 1.2 2.7 1.0 1.3 14.0 0.0 1.4 1.8 6.2 1.6 10.4 2.4 0.0 1.8 4.9 3.4 3.2 2.4 3.0 12.8 23.4 1.1 2.6 2.6 2.6 1.2 7.6 4.2 1.1 1.8 3.9 0.0 32.0 2.0 0.0 6.6 1.9 2.9 1.5 3.8 1.8 14.0 4.6 1.3 24.7 11.1 13.4 1.0 0.6 1.5 5.8 0.7 1.2 2.2 3.7 5.9 0.0 2.4 2.3 10.9 2.7 4.1 1.3 0.1 12.5 2.5 3.5 0.6 FAM83A "BJ-TSA-9, MGC14128" ENSG00000147689 "Family with sequence similarity 83 member A" Q86UY5 8 123178960-123210079 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 111.3;vagina: 55.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 71.2;Club cells: 58.2;Pancreatic endocrine cells: 28.7;Squamous epithelial cells: 19.3;Suprabasal keratinocytes: 15.2;Urothelial cells: 25.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 52.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 83.5;HBEC3-KT: 126.3;hTCEpi: 66.4;K-562: 206.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA052615 Approved Nucleoplasm,Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Cytosol "HPA052615: AB_2797244" "unprognostic (4.48e-2)" "unprognostic (2.03e-3)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (2.49e-1)" "unprognostic (2.68e-1)" "unprognostic (8.67e-2)" "prognostic unfavorable (2.98e-9)" "unprognostic (2.62e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (4.99e-6)" "unprognostic (2.04e-1)" "unprognostic (2.22e-16)" "unprognostic (2.76e-1)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "unprognostic (6.07e-2)" 0.2 0.6 0.0 0.1 0.0 0.2 0.3 0.2 0.1 18.9 0.1 0.1 1.0 0.0 1.3 111.3 4.3 1.0 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.7 0.0 0.1 7.5 6.4 0.1 10.2 2.4 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.4 0.0 7.4 3.8 55.8 0.0 83.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 1.6 0.7 10.6 0.0 0.0 25.9 0.0 126.3 0.0 0.0 0.1 0.8 9.2 0.0 0.0 0.1 0.1 0.0 66.4 0.0 16.8 0.0 0.0 0.1 206.3 0.1 0.0 0.3 0.0 0.1 0.0 4.2 0.1 0.0 0.0 0.1 0.0 18.4 0.1 0.0 14.4 9.7 0.1 0.2 1.5 0.2 0.6 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 4.0 71.2 1.2 0.0 4.4 0.9 1.1 0.0 58.2 1.8 0.0 0.1 0.0 1.0 0.0 0.3 1.0 0.0 0.1 0.1 0.0 0.0 0.6 0.7 0.0 0.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 10.2 0.0 0.4 1.6 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 28.7 0.2 0.0 0.1 0.7 1.1 0.1 9.6 0.0 0.0 0.1 1.4 2.2 0.6 19.3 15.2 0.0 0.1 0.0 0.8 25.0 C8orf76 FLJ14825 ENSG00000189376 "Chromosome 8 open reading frame 76" Q96K31 8 123219967-123241377 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 136.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 164.9" HPA023708 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Cytosol "HPA023708: AB_1845785" "prognostic unfavorable (9.95e-4)" "unprognostic (1.61e-1)" "unprognostic (9.71e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (4.47e-3)" "unprognostic (1.48e-2)" "unprognostic (2.49e-2)" "unprognostic (1.43e-1)" "unprognostic (3.50e-1)" "unprognostic (7.80e-2)" "prognostic unfavorable (5.95e-11)" "unprognostic (1.54e-2)" "unprognostic (1.94e-1)" "unprognostic (3.26e-1)" "unprognostic (2.71e-2)" 10.5 14.1 12.0 9.5 12.8 12.6 10.8 13.3 15.0 9.3 13.3 10.8 9.4 7.7 11.4 15.4 8.9 8.7 13.0 12.0 12.6 9.2 18.4 9.4 14.1 12.3 12.5 8.3 10.8 7.7 17.3 12.2 12.4 10.5 11.8 11.0 12.5 8.1 15.2 8.4 11.1 7.8 12.7 14.3 10.0 7.3 12.6 13.9 9.8 7.9 13.9 10.5 10.3 13.4 24.7 22.4 20.3 14.3 19.5 17.8 13.9 22.7 22.0 26.0 26.1 20.5 17.5 16.8 24.4 21.9 19.4 18.4 22.9 12.4 29.3 27.0 31.9 19.7 10.1 28.0 35.0 10.5 15.6 13.1 23.3 23.3 19.4 15.2 23.4 25.9 28.6 12.8 21.9 72.3 30.7 23.1 16.6 59.4 37.6 16.1 10.4 19.3 22.4 20.1 26.7 24.8 22.7 164.9 25.0 20.6 20.2 24.7 12.9 14.8 28.3 16.1 19.0 16.8 19.8 18.2 15.9 23.7 16.3 19.9 18.3 28.3 13.6 21.4 14.4 11.7 14.8 17.6 19.2 14.8 14.0 14.1 10.9 15.0 18.1 16.8 21.3 13.2 12.0 12.8 13.3 15.0 12.0 12.6 12.3 12.5 12.4 12.7 12.6 13.4 12.4 12.8 2.0 7.2 17.7 13.5 17.8 29.0 17.1 8.2 13.8 13.8 5.9 7.2 25.4 1.8 10.4 27.4 23.4 21.3 5.9 16.4 5.1 10.7 15.4 11.7 24.7 8.6 6.8 11.8 31.5 15.1 8.2 11.5 22.2 10.8 8.9 11.1 22.6 136.3 8.2 12.5 32.6 14.5 17.7 4.0 12.8 16.3 14.2 3.7 21.7 12.9 20.6 3.5 8.8 14.8 13.8 7.5 19.1 21.6 19.4 11.2 48.3 7.7 19.7 11.5 28.7 14.4 17.1 12.6 11.5 40.2 18.1 8.8 15.7 39.9 ZHX1-C8orf76 ENSG00000259305 "ZHX1-C8orf76 readthrough" Q96EF9 8 123226189-123274284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 10.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 26.0" HPA023708 Uncertain Uncertain Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Cytosol "HPA023708: AB_1845785" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (1.37e-2)" "unprognostic (1.83e-3)" "unprognostic (1.13e-1)" "unprognostic (1.16e-1)" "unprognostic (2.49e-3)" "unprognostic (7.10e-2)" "unprognostic (1.91e-2)" "unprognostic (9.34e-3)" "unprognostic (2.29e-1)" "unprognostic (3.09e-2)" "unprognostic (5.64e-11)" "unprognostic (1.79e-1)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.06e-2)" 2.7 2.4 1.4 1.1 1.8 8.5 2.5 2.1 1.8 2.3 1.3 1.8 2.0 1.8 1.8 2.8 2.1 1.1 2.5 1.3 1.4 2.3 2.6 2.9 2.4 1.8 1.7 2.3 1.6 1.1 3.6 1.7 1.6 2.5 2.4 2.9 2.5 1.3 4.1 2.5 1.9 1.6 1.2 3.0 1.8 1.4 1.9 2.2 2.1 1.9 2.7 1.9 2.3 2.3 3.4 4.3 3.1 2.2 1.9 2.1 2.0 1.5 1.5 3.6 2.7 3.5 2.6 2.0 1.3 2.5 2.1 2.2 3.5 1.9 5.4 3.5 7.3 5.9 3.1 4.2 1.9 1.2 3.1 2.8 2.8 2.9 1.8 1.5 4.2 5.9 4.9 2.8 3.2 10.6 5.0 3.9 0.8 6.8 4.7 3.9 2.0 2.8 2.5 3.4 4.8 3.4 3.0 26.0 1.6 1.7 3.9 1.1 0.3 1.5 3.0 2.5 3.4 3.9 5.2 4.3 2.1 3.2 1.1 1.7 2.9 4.8 2.0 4.1 1.9 2.7 2.6 1.8 2.5 2.9 2.1 1.8 1.0 2.7 2.9 2.3 4.9 2.0 1.4 1.8 2.1 1.8 1.3 1.4 1.8 1.7 1.6 1.2 1.9 2.3 2.5 0.0 1.1 4.6 2.0 3.1 5.3 2.5 0.0 0.4 2.2 2.0 1.1 1.5 2.7 3.7 0.0 1.9 5.2 0.9 1.9 1.8 1.4 1.0 1.0 1.7 3.0 0.0 2.0 1.8 2.6 1.8 0.0 0.8 0.0 1.7 2.2 0.8 2.7 10.1 2.8 2.2 4.1 1.3 2.1 1.4 0.9 2.0 1.8 0.0 2.4 0.9 3.1 4.5 4.9 2.2 0.5 1.2 0.7 2.9 1.6 1.3 4.3 1.4 0.0 1.6 1.4 2.7 2.5 0.4 1.4 1.0 1.3 0.8 1.4 7.0 ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055357 Supported Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "HPA055357: AB_2682793" "unprognostic (4.36e-3)" "unprognostic (6.73e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (6.09e-4)" "unprognostic (8.73e-3)" "unprognostic (5.61e-2)" "unprognostic (9.22e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (6.00e-2)" "unprognostic (7.97e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (6.63e-2)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.76e-2)" 28.2 14.8 24.5 12.1 24.3 13.5 18.7 27.0 28.1 20.8 21.3 15.6 18.4 17.4 15.2 37.0 18.5 15.1 15.2 23.3 31.9 22.9 39.5 14.4 12.6 25.4 27.7 20.8 17.2 22.8 12.7 14.3 26.5 17.9 14.8 35.0 17.4 18.6 15.5 27.8 19.3 19.2 23.1 15.8 14.8 10.1 24.1 19.8 37.7 19.4 15.0 19.8 17.9 29.4 29.7 13.2 18.0 21.3 34.3 28.3 11.6 35.3 19.6 25.6 29.6 23.5 12.4 44.7 46.1 42.8 11.4 19.6 51.3 32.5 32.4 89.5 26.5 72.6 29.1 14.2 23.3 26.9 33.3 21.4 36.9 35.1 30.0 21.9 20.5 21.2 86.0 34.1 38.3 89.7 62.0 12.1 4.8 62.1 27.7 31.3 16.2 32.0 22.9 66.0 86.3 32.1 40.3 113.6 14.1 10.5 45.4 30.6 19.3 40.1 53.4 32.6 23.8 32.1 95.1 49.6 27.2 49.7 11.2 1.5 3.6 3.6 3.8 6.4 4.8 3.3 4.8 3.5 4.9 3.9 4.5 4.8 1.3 6.5 14.0 2.7 5.7 2.9 24.5 24.3 27.0 28.1 23.3 31.9 25.4 27.7 26.5 23.1 24.1 29.4 35.0 25.6 25.7 0.0 15.7 37.1 28.0 19.7 47.3 46.3 28.8 27.1 30.7 25.8 26.8 20.2 47.9 10.4 22.8 33.5 31.3 16.6 10.9 13.0 52.5 30.8 43.3 19.8 0.0 22.3 6.6 33.0 19.4 13.8 28.5 19.1 28.9 71.5 15.0 146.4 0.0 23.1 14.2 24.2 19.0 21.7 46.6 19.4 26.6 0.0 20.5 46.3 27.8 0.0 0.0 16.7 25.8 64.3 15.3 21.2 35.8 33.2 21.4 34.3 39.5 34.4 38.0 38.5 27.6 84.4 62.5 9.6 20.0 27.0 22.8 29.2 ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 79.1;Spermatocytes: 106.0;Spermatogonia: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 294.4" "Low region specificity" "Detected in all" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 33: Neutrophils - Chromatin organization" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB056158: AB_2665580, HPA029424: AB_10611680" "unprognostic (1.56e-1)" "unprognostic (4.55e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.08e-1)" "unprognostic (4.44e-2)" "unprognostic (2.98e-2)" "unprognostic (2.74e-3)" "unprognostic (2.02e-3)" "unprognostic (5.62e-2)" "unprognostic (1.19e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (8.33e-15)" "unprognostic (1.15e-2)" "unprognostic (1.82e-1)" "unprognostic (4.84e-2)" "unprognostic (6.17e-2)" 2.9 3.4 3.8 7.7 3.6 26.5 6.8 2.6 3.9 12.8 2.0 5.3 5.0 4.3 3.8 6.8 3.4 3.2 5.8 3.2 4.5 1.4 9.9 4.1 14.4 2.9 3.8 7.0 3.3 1.9 3.9 4.8 2.6 10.3 6.9 1.4 4.3 4.7 9.3 6.8 5.2 4.1 2.8 4.9 4.7 18.9 5.1 28.3 3.9 3.2 12.8 4.8 3.9 2.8 103.7 39.6 55.0 19.0 9.7 12.3 24.3 79.2 27.2 66.8 73.9 30.1 43.8 67.2 23.6 25.2 26.5 48.3 74.2 25.6 106.1 94.3 39.0 121.2 41.0 61.4 3.8 44.6 57.4 4.1 3.8 63.6 21.0 14.3 20.7 38.6 57.7 66.4 50.4 107.1 129.5 32.8 10.0 77.8 38.4 66.5 65.6 36.4 23.8 46.7 70.2 30.5 114.4 294.4 20.8 22.1 60.2 41.2 13.0 50.4 69.3 40.2 96.6 21.2 40.7 60.8 32.9 72.9 40.4 5.3 0.8 3.3 1.6 0.8 2.2 2.6 2.3 2.7 1.4 1.5 1.5 1.7 0.2 2.5 1.9 0.1 4.6 1.0 3.8 3.6 2.6 3.9 3.2 4.5 2.9 3.8 2.6 2.8 5.1 2.8 4.8 6.4 11.0 9.4 18.5 15.8 27.9 9.1 14.2 2.8 17.3 21.2 27.3 2.8 10.2 3.7 4.2 14.9 15.3 9.0 1.9 3.5 54.9 7.9 17.3 9.6 1.2 79.1 25.6 2.2 26.2 17.1 13.3 17.5 14.5 37.9 7.1 16.3 11.2 1.7 16.4 13.1 4.1 8.2 6.9 24.4 7.5 11.7 1.8 14.0 6.3 6.3 17.5 11.6 2.8 3.5 4.3 13.9 34.0 20.7 3.1 1.0 5.4 1.9 0.0 9.5 17.5 106.0 82.4 23.7 12.1 13.5 22.8 3.7 14.6 24.5 NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 21.9;Cytotrophoblasts: 13.9;Extravillous trophoblasts: 23.0;Hofbauer cells: 13.2;Syncytiotrophoblasts: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: AB_2682228" "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 7.1 10.9 16.2 5.1 16.7 5.9 13.5 16.3 24.0 12.8 15.5 7.5 4.3 8.1 8.9 6.9 7.5 6.7 20.1 14.8 17.8 13.0 6.8 6.8 7.4 17.0 17.9 18.2 9.6 11.0 10.5 6.8 17.4 10.2 7.9 14.9 6.9 8.8 16.0 7.7 4.4 9.5 15.8 5.2 8.5 12.7 20.0 7.1 12.8 17.6 10.1 8.8 7.2 17.7 26.6 26.9 39.2 18.1 15.3 40.9 14.5 19.1 21.3 23.4 26.1 15.8 17.8 19.7 19.8 23.8 32.7 12.8 25.8 29.7 31.4 53.1 15.8 25.6 13.2 22.4 21.2 12.7 10.9 24.1 16.0 29.3 32.8 27.1 22.6 41.2 18.8 29.0 33.5 84.3 30.2 14.4 12.3 65.6 20.5 13.5 20.0 20.4 31.1 22.6 18.6 34.1 20.7 109.0 35.8 44.5 17.6 12.2 9.8 26.5 46.2 19.7 26.4 17.4 38.1 24.1 18.8 14.1 19.1 16.3 5.7 2.1 6.2 8.7 7.4 5.0 7.3 7.7 9.0 4.1 6.2 6.9 1.5 16.0 3.8 5.2 10.6 4.6 16.2 16.7 16.3 24.0 14.8 17.8 17.0 17.9 17.4 15.8 20.0 17.7 5.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 13.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 23.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.0 0.3 0.0 0.0 0.0 FBXO32 "ATROGIN1, Fbx32, MAFbx" ENSG00000156804 "F-box protein 32" Q969P5 8 123497889-123541206 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 649.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 247.5;Cardiomyocytes: 286.5;Prostatic glandular cells: 225.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 2.9;gdT-cell: 2.5;MAIT T-cell: 2.5;memory CD4 T-cell: 3.6;memory CD8 T-cell: 3.8;naive CD4 T-cell: 4.2;naive CD8 T-cell: 5.4;NK-cell: 3.2;T-reg: 3.8" "Group enriched" "Detected in many" 8 "granulocytes: 2.9;NK-cells: 3.2;T-cells: 5.4" "Cell line enhanced" "Detected in many" "GAMG: 49.3;HDLM-2: 176.1;hTERT-RPE1: 58.3;U-251 MG: 51.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058955, HPA065209" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "HPA058955: , HPA065209: AB_2685433" "unprognostic (2.55e-1)" "unprognostic (3.62e-1)" "unprognostic (1.80e-1)" "unprognostic (1.54e-2)" "unprognostic (1.91e-1)" "unprognostic (1.25e-1)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.31e-1)" "unprognostic (1.10e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (6.73e-4)" "unprognostic (8.58e-3)" "unprognostic (1.40e-1)" "unprognostic (1.09e-1)" "unprognostic (7.97e-3)" 10.9 2.7 13.2 13.9 19.6 2.2 29.2 20.0 15.5 15.0 41.4 136.6 6.7 86.9 14.9 16.2 59.5 32.5 77.9 10.6 15.1 2.7 1.1 3.8 6.0 27.4 20.3 24.9 4.6 11.7 8.9 7.7 28.8 25.8 20.7 17.9 23.0 43.8 649.5 12.9 23.5 94.9 21.5 3.9 31.8 1.7 15.9 9.2 24.3 105.6 5.1 73.3 13.8 28.6 5.3 0.9 0.2 0.0 10.6 2.5 1.9 1.0 11.4 0.6 1.1 0.0 2.9 0.0 3.1 8.5 49.3 0.3 0.2 1.0 0.9 176.1 4.0 0.0 6.3 0.0 14.5 0.1 0.7 21.1 7.4 2.6 3.2 58.3 0.8 2.5 0.3 1.5 0.8 1.3 0.7 0.1 0.1 2.1 0.9 0.0 0.2 1.1 1.9 1.7 0.3 1.1 1.2 19.2 21.5 1.1 18.9 0.4 0.7 3.1 0.8 1.1 51.9 17.4 2.6 0.4 12.7 0.2 2.5 2.9 0.2 0.0 2.5 0.1 2.5 0.4 3.6 3.8 0.2 0.4 4.2 5.4 0.1 3.2 0.2 0.1 3.8 1.1 13.2 19.6 20.0 15.5 10.6 15.1 27.4 20.3 28.8 21.5 15.9 28.6 6.8 0.0 3.7 7.5 6.1 11.5 184.8 113.3 64.9 17.7 44.9 247.5 286.5 4.3 63.6 7.3 35.5 17.8 27.9 153.0 9.8 14.4 4.7 22.2 88.2 13.0 102.4 8.0 52.2 30.7 17.5 28.9 14.8 76.0 0.0 30.3 2.2 2.9 5.3 21.9 30.9 63.6 111.9 5.9 3.4 3.5 39.7 5.6 44.4 14.0 2.4 58.6 25.7 9.5 117.2 51.7 189.5 61.3 38.3 225.2 36.9 5.2 19.9 100.1 19.7 75.2 61.3 15.9 2.9 49.9 6.3 109.2 32.5 3.7 21.1 90.8 KLHL38 C8ORFK36 ENSG00000175946 "Kelch like family member 38" Q2WGJ6 8 123645527-123652950 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 56.7;skeletal muscle: 268.3;tongue: 76.9" "Cell type enriched" "Detected in single" 10 "Cardiomyocytes: 1.0" "Group enriched" "Detected in some" 5 "breast cancer: 1.3;melanoma: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;SK-BR-3: 2.8;U-2197: 4.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024770, HPA027115" Uncertain Approved Nucleoplasm,Cytosol Yes NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm Cytosol "HPA024770: AB_10599286, HPA027115: AB_10599950" "unprognostic (8.62e-3)" "unprognostic (3.86e-3)" "unprognostic (1.02e-2)" "unprognostic (8.94e-2)" "unprognostic (4.68e-1)" "unprognostic (2.09e-2)" "unprognostic (8.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.54e-1)" "unprognostic (4.02e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-2)" "unprognostic (5.73e-6)" "unprognostic (8.46e-3)" "unprognostic (3.82e-2)" "unprognostic (6.52e-2)" "unprognostic (2.84e-2)" 0.2 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.5 0.2 0.1 0.9 0.1 1.3 0.0 2.5 0.7 0.7 56.7 0.2 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.1 1.3 0.0 1.5 0.0 0.8 0.1 0.0 0.7 0.1 268.3 0.2 0.2 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 76.9 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.9 0.0 0.5 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 144.3;intestine: 293.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 180.1;Enteroendocrine cells: 44.9;Intestinal goblet cells: 161.1;Paneth cells: 58.1;Proximal enterocytes: 125.2;Undifferentiated cells: 38.5" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A549: 27.8;HDLM-2: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" 0.2 0.0 1.1 1.6 2.6 0.0 0.4 2.6 2.2 0.4 1.1 21.6 293.6 1.5 2.2 0.2 58.4 144.3 0.1 1.1 1.5 7.0 20.2 0.2 0.2 4.1 2.9 0.4 0.4 0.0 0.0 0.0 3.3 0.5 36.1 4.3 0.1 24.3 0.0 0.1 219.5 2.9 3.3 0.0 0.8 4.2 2.1 0.1 0.0 0.0 0.0 0.5 0.1 5.3 0.0 27.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 14.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.0 0.0 0.0 0.0 1.7 1.6 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.6 2.6 2.2 1.1 1.5 4.1 2.9 3.3 3.3 2.1 5.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.2 0.1 1.1 0.4 180.1 0.0 0.0 0.0 0.0 0.0 6.2 3.9 1.4 1.1 4.5 3.6 0.2 44.9 2.7 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.2 0.0 1.0 161.1 0.0 0.0 0.0 1.4 1.2 0.3 0.0 0.0 0.0 0.3 0.0 0.5 1.2 0.1 58.1 0.0 0.0 0.0 125.2 27.6 2.9 10.9 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.4 0.1 38.5 0.1 FAM91A1 FLJ23790 ENSG00000176853 "Family with sequence similarity 91 member A1" Q658Y4 8 123768439-123815452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027978 Approved Approved Nucleoplasm,Microtubules NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Microtubules" "HPA027978: AB_10600004" "unprognostic (2.21e-2)" "unprognostic (6.13e-2)" "unprognostic (2.95e-2)" "unprognostic (4.56e-3)" "unprognostic (2.39e-1)" "unprognostic (3.80e-2)" "unprognostic (4.42e-3)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (8.55e-2)" "unprognostic (2.30e-2)" "unprognostic (1.16e-1)" "unprognostic (1.31e-1)" "unprognostic (1.50e-1)" "unprognostic (2.58e-1)" "unprognostic (5.40e-2)" "unprognostic (6.19e-2)" 12.9 11.7 6.8 15.9 7.9 42.9 14.0 8.4 8.2 12.8 12.2 13.0 14.5 13.8 11.9 13.1 10.3 16.0 7.1 7.0 9.0 18.4 26.6 13.1 18.7 9.1 8.2 12.8 14.0 21.0 9.3 20.2 8.6 11.6 14.8 11.7 11.4 11.0 6.1 11.6 14.2 11.7 8.7 19.6 13.9 10.9 8.5 14.3 18.3 6.2 17.0 17.1 10.6 11.6 63.9 42.4 12.9 22.4 24.4 26.3 20.8 36.2 39.4 33.7 42.5 21.3 25.8 29.9 39.2 29.9 26.7 30.4 30.8 39.2 60.0 57.5 29.8 47.2 21.9 25.6 38.0 21.7 58.9 25.0 31.1 44.1 54.3 23.0 31.0 18.4 17.1 41.3 30.7 75.8 37.7 14.4 12.7 51.8 37.3 20.4 21.5 22.4 28.4 64.7 15.5 21.6 48.1 102.4 49.8 18.8 31.5 22.9 31.5 32.0 57.4 35.7 53.1 31.9 65.8 28.4 50.2 38.7 39.9 7.0 8.0 11.3 3.2 9.5 2.9 5.1 3.2 2.7 8.2 4.2 2.7 3.7 10.1 5.9 8.5 3.1 3.1 4.3 6.8 7.9 8.4 8.2 7.0 9.0 9.1 8.2 8.6 8.7 8.5 11.6 31.9 25.6 13.2 17.6 30.6 39.6 21.9 19.0 20.5 15.0 24.0 17.7 8.4 22.8 19.3 25.8 22.9 10.4 25.3 21.3 5.9 12.1 22.4 20.8 22.9 27.5 27.5 10.3 21.0 15.5 12.7 19.3 26.5 33.0 8.8 18.2 18.5 59.3 27.1 23.5 22.0 22.0 16.2 73.6 43.5 26.0 14.0 45.9 21.4 24.4 40.1 17.6 19.6 23.6 45.8 35.1 21.7 14.7 25.8 34.8 18.7 20.8 16.5 21.7 13.1 26.5 22.4 14.2 10.7 27.0 46.7 19.2 19.6 16.0 14.5 45.3 FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "intestine: 10.8;stomach 1: 43.1" "Group enriched" "Detected in some" 9 "Early spermatids: 15.8;Gastric mucus-secreting cells: 39.3;Intestinal goblet cells: 10.4;Late spermatids: 30.5;Pancreatic endocrine cells: 10.8" "Group enriched" "Detected in some" 6 "pancreatic cancer: 4.2;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;ASC TERT1: 1.8;BJ hTERT+: 1.2;PC-3: 1.7;U-87 MG: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054117 Enhanced NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "HPA054117: AB_2682387" "unprognostic (1.90e-1)" "unprognostic (3.08e-3)" "unprognostic (2.06e-3)" "unprognostic (3.91e-2)" "unprognostic (2.09e-1)" "unprognostic (9.49e-3)" "unprognostic (1.36e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.55e-2)" "unprognostic (3.32e-2)" "unprognostic (3.23e-6)" "unprognostic (7.09e-2)" "unprognostic (8.43e-2)" "unprognostic (2.79e-3)" "unprognostic (6.39e-2)" 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.2 0.3 0.0 5.0 2.9 0.0 0.0 0.1 0.2 0.0 0.1 0.4 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.1 0.0 4.5 0.1 0.0 0.0 43.1 2.5 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.0 0.0 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.5 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.7 0.0 1.8 0.0 0.0 0.0 0.0 0.6 0.0 0.4 15.8 0.3 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 39.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.4 0.0 0.0 0.0 30.5 0.9 0.0 0.0 1.9 0.0 0.0 0.0 1.0 1.0 10.8 2.2 0.0 0.1 0.0 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.8 TMEM65 ENSG00000164983 "Transmembrane protein 65" Q6PI78 8 124306189-124372701 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.6;Horizontal cells: 99.3;Inhibitory neurons: 139.8;Microglial cells: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025020 Uncertain NA NA "Cluster 37: B-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA025020: AB_2205178" "prognostic unfavorable (2.17e-4)" "unprognostic (3.52e-2)" "unprognostic (2.97e-2)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.24e-1)" "unprognostic (7.74e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (2.26e-2)" "unprognostic (1.84e-1)" "unprognostic (4.71e-2)" "unprognostic (7.95e-2)" "unprognostic (8.26e-2)" "unprognostic (5.67e-2)" "unprognostic (8.25e-2)" "unprognostic (1.75e-1)" "unprognostic (1.41e-1)" "unprognostic (3.78e-1)" 3.7 3.1 5.1 4.9 5.1 3.5 5.1 5.2 5.4 5.5 3.4 4.0 15.4 4.8 2.2 5.6 3.0 4.7 11.9 4.9 5.0 4.7 2.7 3.6 4.5 3.8 5.8 4.2 4.8 6.6 2.1 3.3 4.8 2.8 4.5 2.7 8.6 2.0 13.9 10.1 5.5 3.7 3.7 4.7 2.8 1.7 6.2 3.7 5.3 12.4 4.5 3.2 5.3 4.6 7.9 5.4 11.2 4.0 3.4 6.1 0.9 4.5 4.4 6.9 7.9 0.9 3.1 7.4 4.4 8.0 5.3 3.6 5.8 4.3 8.2 23.2 5.9 5.0 4.6 1.6 9.5 3.4 4.8 4.4 8.1 10.0 7.9 9.4 15.8 3.6 2.3 6.2 8.5 6.1 2.4 1.3 3.0 3.5 7.5 1.4 10.6 4.5 7.3 3.4 9.1 5.4 16.6 41.9 7.8 5.7 3.7 4.3 10.3 5.8 13.9 19.4 7.7 4.2 3.3 3.0 8.2 24.6 8.4 0.4 0.1 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.0 0.2 0.2 0.2 0.3 0.4 0.1 0.2 0.3 0.0 5.1 5.1 5.2 5.4 4.9 5.0 3.8 5.8 4.8 3.7 6.2 4.6 14.0 12.8 3.9 34.3 15.1 13.4 9.4 3.0 11.4 6.0 14.0 11.8 37.2 15.7 4.8 7.3 0.0 0.6 10.0 17.0 23.5 10.9 3.9 12.1 12.9 14.0 1.2 6.3 72.6 7.8 1.6 13.0 5.6 9.7 1.3 31.2 23.9 4.7 8.9 99.3 139.8 3.7 4.1 19.1 10.5 1.0 9.9 19.8 8.8 70.3 9.3 4.4 14.4 52.3 45.0 9.8 4.7 11.7 10.2 7.8 5.3 19.2 5.8 2.3 6.6 25.9 8.9 3.3 4.5 31.9 12.5 0.7 14.8 7.5 5.2 11.6 TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 73.1" "Low region specificity" "Detected in all" HPA023939 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 22: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Mitochondria "HPA023939: AB_1848793" "unprognostic (2.54e-2)" "unprognostic (2.20e-1)" "unprognostic (7.81e-2)" "unprognostic (1.02e-2)" "unprognostic (8.75e-2)" "prognostic unfavorable (2.99e-5)" "prognostic unfavorable (5.10e-4)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.51e-1)" "unprognostic (6.56e-2)" "unprognostic (4.72e-3)" "unprognostic (3.39e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.25e-4)" "unprognostic (1.04e-2)" 6.0 5.8 5.0 5.4 5.1 3.1 8.7 4.3 6.7 6.5 5.5 5.7 4.6 6.5 6.1 5.6 7.6 4.4 5.9 6.5 4.8 7.6 6.0 5.9 6.5 3.6 3.9 5.0 5.1 8.6 4.7 5.4 4.1 6.9 6.5 8.1 7.7 6.1 9.7 5.3 5.0 8.2 3.4 5.5 5.7 6.4 5.5 8.3 8.8 10.0 6.7 6.7 4.3 4.9 14.8 12.6 10.3 8.1 19.0 9.7 2.5 9.1 10.6 13.1 11.2 7.7 10.0 14.9 12.3 9.4 8.5 10.1 14.7 14.9 15.4 14.8 11.2 14.4 12.8 2.6 14.8 0.0 11.2 12.1 19.6 12.9 16.2 3.8 11.1 15.4 20.4 10.1 8.2 73.1 17.2 6.1 0.0 33.9 11.5 5.4 6.9 9.9 12.1 15.7 17.3 13.8 13.4 49.5 19.5 8.7 14.1 6.1 8.9 9.1 23.8 6.8 10.4 10.4 15.6 5.8 8.2 5.0 7.5 0.4 3.5 3.8 2.3 2.9 3.0 2.1 3.2 2.5 2.8 2.8 3.9 3.9 1.3 3.1 3.3 0.8 2.1 2.4 5.0 5.1 4.3 6.7 6.5 4.8 3.6 3.9 4.1 3.4 5.5 4.9 4.9 9.6 7.5 2.0 11.2 5.2 6.1 3.5 7.4 5.6 5.5 4.7 3.9 7.2 2.2 3.7 16.7 7.3 8.4 4.2 5.9 5.6 18.6 6.3 4.9 5.7 3.0 1.7 1.5 6.2 5.4 4.5 6.6 3.6 9.5 7.7 4.2 5.4 5.1 8.4 1.8 4.4 4.1 4.1 2.5 21.0 4.1 5.2 5.4 1.0 8.1 4.0 9.2 1.0 1.2 4.3 3.9 6.0 8.4 4.8 3.9 8.2 7.6 8.2 0.0 8.2 6.5 14.2 5.8 4.7 4.3 4.9 6.3 7.9 4.9 4.6 RNF139 "HRCA1, RCA1, TRC8" ENSG00000170881 "Ring finger protein 139" Q8WU17 8 124474880-124488618 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Ubl conjugation pathway" "Receptor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 93.2" "Group enriched" "Detected in all" 10 "Early spermatids: 810.1;Late spermatids: 992.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001202 Approved NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 34: Spermatids - Unknown function" "HPA001202: AB_1079824" "unprognostic (3.28e-3)" "unprognostic (2.92e-2)" "unprognostic (5.16e-2)" "unprognostic (5.43e-2)" "unprognostic (1.03e-1)" "unprognostic (8.32e-3)" "unprognostic (2.71e-2)" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (3.54e-4)" "unprognostic (9.85e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (2.75e-1)" "unprognostic (7.75e-2)" "unprognostic (1.45e-1)" 23.5 20.8 10.0 15.9 11.1 93.2 18.9 14.8 12.7 16.6 11.2 15.6 9.2 20.2 13.6 16.5 16.7 16.8 15.3 11.0 11.0 15.3 26.1 16.6 17.3 11.0 10.8 23.6 14.4 11.8 10.2 19.4 11.0 14.9 14.8 12.4 16.5 13.3 20.3 17.2 14.2 20.3 11.8 13.9 13.9 68.7 11.7 19.3 16.3 22.6 14.8 16.7 12.4 15.0 26.6 17.1 21.6 20.3 43.2 34.1 16.6 23.5 44.4 18.6 24.7 10.9 21.6 27.5 27.8 31.7 14.3 19.7 18.3 28.4 28.9 37.6 24.5 41.1 11.9 22.9 33.3 19.6 23.2 30.5 41.0 20.5 55.9 27.1 26.2 26.8 29.1 41.3 22.2 70.2 32.9 13.6 14.3 52.6 25.6 13.2 14.9 27.0 35.3 34.4 9.4 22.3 31.0 76.5 33.4 16.5 35.7 20.7 20.6 13.9 29.7 22.2 26.3 32.9 40.9 28.6 19.9 31.7 13.9 2.7 6.2 10.1 8.7 4.1 11.0 7.9 7.8 10.5 8.4 7.1 8.1 8.4 8.5 7.2 11.4 4.0 11.4 6.7 10.0 11.1 14.8 12.7 11.0 11.0 11.0 10.8 11.0 11.8 11.7 15.0 21.1 3.2 8.4 11.8 66.2 66.2 62.1 27.2 58.6 14.5 31.6 19.7 16.2 34.3 18.5 22.0 6.2 42.3 58.5 22.5 11.7 19.9 810.1 31.3 22.6 24.9 21.7 27.1 12.9 18.0 55.9 40.1 23.4 37.1 20.3 23.2 22.9 31.8 25.0 16.8 12.8 18.5 10.2 33.7 74.4 992.2 29.5 43.4 35.6 12.2 26.5 21.3 26.8 8.5 18.5 22.5 11.4 27.1 35.4 41.1 17.0 16.9 20.1 22.7 19.7 39.7 49.2 62.3 24.3 46.7 70.5 75.5 83.5 22.6 18.2 55.5 TATDN1 CDA11 ENSG00000147687 "TatD DNase domain containing 1" Q6P1N9 8 124488485-124539458 "Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023634, HPA053045" Uncertain Supported Nucleoplasm NA NA 660000 "Cluster 41: Basophils - Cellular respiration" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" Nucleoplasm "HPA023634: AB_1857779, HPA053045: AB_2682024" "unprognostic (2.19e-3)" "unprognostic (3.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-2)" "unprognostic (1.65e-1)" "unprognostic (1.23e-2)" "unprognostic (1.54e-3)" "unprognostic (2.28e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (2.53e-4)" "unprognostic (2.50e-1)" "unprognostic (6.33e-3)" "unprognostic (3.44e-2)" "unprognostic (4.30e-2)" "unprognostic (2.24e-1)" "unprognostic (5.12e-2)" 23.4 18.7 16.0 15.8 16.8 16.9 39.1 16.8 21.9 20.1 13.0 21.2 18.1 23.5 21.0 16.4 23.5 14.6 23.1 16.1 17.1 28.1 25.2 14.8 19.8 17.0 16.9 39.5 44.8 24.4 8.9 13.6 18.5 17.2 22.4 13.7 27.7 15.0 52.2 20.4 18.1 19.7 17.1 12.2 22.7 12.3 16.4 27.1 36.9 43.9 20.0 21.0 17.3 19.4 65.5 45.1 42.5 30.2 36.8 69.9 31.9 35.5 38.1 43.3 40.0 44.7 69.1 49.7 77.4 38.6 33.6 53.7 52.0 51.9 71.6 64.0 34.3 45.6 36.5 39.1 70.2 35.5 17.0 52.5 80.5 63.5 132.4 48.3 35.3 48.4 38.1 31.4 59.1 198.4 52.8 21.6 42.7 132.8 58.8 35.4 31.7 55.7 61.3 45.5 35.7 49.2 39.2 80.3 87.2 39.3 52.7 38.1 28.4 30.8 82.7 57.3 96.7 40.0 65.3 62.1 57.9 61.4 27.1 29.3 11.0 4.3 12.8 9.1 19.1 17.2 19.5 16.2 15.6 16.6 27.7 24.8 2.1 17.7 6.6 14.0 22.5 14.8 16.0 16.8 16.8 21.9 16.1 17.1 17.0 16.9 18.5 17.1 16.4 19.4 39.8 16.0 27.1 25.5 37.0 64.7 100.9 129.4 75.7 19.3 79.5 131.4 23.9 21.5 55.6 27.6 14.6 66.6 26.7 17.8 107.6 55.2 7.0 40.1 43.0 31.9 16.2 23.8 36.6 62.0 62.5 42.7 29.6 44.4 20.8 76.5 26.7 40.2 54.6 16.8 35.2 41.6 65.1 36.7 43.6 6.7 49.7 36.3 48.0 30.0 51.6 24.8 37.0 20.1 48.6 40.8 34.3 34.6 34.1 94.2 57.8 128.9 33.8 19.2 19.7 64.7 57.5 34.6 45.1 54.0 58.2 59.7 38.9 68.6 60.7 82.6 NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1314.9;tongue: 1486.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 2950.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042768 Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Mitochondria "HPA042768: AB_10797508" "unprognostic (1.18e-2)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-3)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (3.80e-2)" "unprognostic (1.51e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.42e-5)" "unprognostic (9.54e-2)" "unprognostic (9.64e-2)" "unprognostic (4.94e-2)" "unprognostic (2.74e-1)" 155.6 158.2 259.0 78.5 263.8 265.2 157.8 281.1 381.2 109.7 245.0 226.4 184.6 129.5 147.4 209.2 126.0 70.4 789.5 257.6 288.7 324.9 325.0 122.9 96.5 279.3 277.8 107.1 209.4 282.9 124.0 81.2 281.5 117.8 191.0 135.8 210.9 115.1 1314.9 149.3 162.9 111.1 253.4 116.8 241.2 204.7 286.2 102.8 154.2 1486.4 104.1 139.9 124.7 274.1 348.2 316.8 236.1 321.2 240.6 204.2 196.0 165.2 189.3 297.4 222.4 417.7 327.6 341.0 421.0 193.6 153.9 385.5 347.3 266.7 279.9 395.8 464.8 831.3 199.6 505.9 320.8 261.8 218.2 239.6 382.1 271.9 587.9 160.1 275.9 241.1 523.7 277.6 243.4 1089.0 415.8 522.7 237.5 1247.0 692.7 276.3 179.9 468.0 400.0 288.8 326.6 255.0 362.4 2950.7 382.8 141.1 407.3 348.2 219.7 172.5 444.1 162.9 399.5 354.8 517.7 392.5 298.6 515.4 233.1 302.2 253.1 136.2 210.5 179.2 209.6 260.9 275.8 237.1 247.5 201.4 269.1 223.9 49.2 188.9 136.1 183.1 346.0 345.8 259.0 263.8 281.1 381.2 257.6 288.7 279.3 277.8 281.5 253.4 286.2 274.1 169.0 125.0 124.8 7.8 147.7 217.8 277.5 448.3 178.7 77.4 247.3 313.0 1005.6 260.2 267.3 286.9 98.0 494.6 119.9 525.0 800.3 338.0 389.8 120.7 100.6 164.1 233.7 227.6 10.5 405.7 296.0 187.9 169.7 109.2 139.4 149.9 167.4 517.7 380.6 37.0 14.9 421.0 488.3 206.0 137.6 865.4 158.8 183.0 247.3 15.9 226.3 144.1 171.0 7.1 18.2 378.1 450.0 152.7 169.1 290.3 584.6 789.7 208.6 91.1 170.9 221.2 511.8 317.6 264.8 377.0 188.4 523.0 155.6 216.0 521.7 315.8 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 ZNF572 FLJ38002 ENSG00000180938 "Zinc finger protein 572" Q7Z3I7 8 124973295-124979389 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.9;Inhibitory neurons: 2.5;Microglial cells: 2.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 2.7;Spermatogonia: 2.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 4.1" "Low region specificity" "Detected in all" HPA066838 Approved Approved "Nuclear speckles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles" "HPA066838: AB_2685734" "unprognostic (8.65e-2)" "unprognostic (3.11e-1)" "unprognostic (5.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.49e-3)" "unprognostic (8.37e-2)" "unprognostic (4.11e-2)" "unprognostic (1.81e-2)" "unprognostic (3.36e-1)" "unprognostic (8.88e-2)" "unprognostic (8.67e-2)" "unprognostic (2.42e-2)" "unprognostic (1.43e-1)" "unprognostic (8.95e-3)" "unprognostic (2.89e-1)" "unprognostic (2.82e-1)" "unprognostic (6.17e-2)" 0.6 0.3 0.9 1.0 1.3 0.1 1.8 1.0 1.2 1.1 0.7 1.0 0.9 1.4 2.2 0.5 1.5 0.7 0.9 0.8 1.0 1.7 0.9 0.7 1.9 1.4 1.1 2.3 1.0 0.6 0.4 1.5 1.1 1.4 1.3 1.9 1.3 1.5 0.2 0.8 0.9 0.8 1.1 1.5 1.4 3.6 1.1 1.9 1.8 0.2 1.9 1.1 0.8 1.6 1.0 0.5 1.1 0.0 1.5 1.7 0.0 0.3 0.1 1.3 0.7 1.4 0.7 2.5 1.6 0.4 0.2 1.9 0.6 0.0 1.1 0.0 0.5 0.0 0.7 1.7 1.2 0.0 1.2 1.3 1.6 1.3 0.0 0.3 0.8 0.0 1.5 0.0 1.7 4.1 0.0 0.0 0.0 2.4 0.0 1.6 2.8 0.3 0.7 0.7 2.5 2.4 1.5 2.4 2.6 2.1 1.0 1.6 0.5 1.5 1.7 0.4 0.0 0.0 1.4 1.1 0.3 0.0 0.1 0.0 0.1 0.3 0.2 0.3 0.4 0.6 0.2 0.1 0.1 0.6 0.8 0.5 0.0 0.7 0.2 0.0 0.0 0.1 0.9 1.3 1.0 1.2 0.8 1.0 1.4 1.1 1.1 1.1 1.1 1.6 0.2 0.0 0.0 3.9 0.8 0.1 0.2 0.0 0.0 1.0 0.3 0.4 0.6 0.0 0.6 0.0 0.0 0.9 0.2 0.2 1.9 0.3 0.5 0.9 0.5 0.4 0.0 0.4 1.3 0.2 0.3 0.4 0.0 0.3 0.0 1.6 0.4 0.3 0.4 0.0 2.5 0.1 0.0 0.3 0.0 0.4 0.0 0.2 0.0 2.8 0.6 2.3 1.0 2.5 2.7 0.0 0.1 1.2 0.0 0.1 0.1 1.0 0.9 0.6 0.0 0.1 0.2 2.4 2.8 0.3 0.0 0.3 0.3 0.5 0.6 0.1 SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" 8.6 31.1 17.5 19.6 27.0 23.0 22.1 26.8 24.0 30.7 25.4 21.6 31.0 16.4 9.1 78.7 18.6 10.7 7.2 18.6 24.4 17.1 72.3 30.9 17.7 47.3 27.7 14.3 10.7 22.7 16.5 47.5 35.1 25.0 18.6 17.8 19.1 7.6 1.4 49.4 14.0 12.3 27.6 9.7 21.8 59.4 21.8 14.2 10.5 1.6 29.4 14.7 46.2 34.6 135.5 51.5 301.6 87.2 91.7 154.1 30.5 34.9 106.3 46.5 84.7 70.6 192.3 92.7 49.2 43.2 186.0 101.0 127.3 192.4 53.6 77.1 268.3 265.2 32.6 181.1 134.6 31.5 74.6 106.1 201.4 138.8 113.3 29.8 51.5 64.2 153.8 174.8 38.1 223.7 109.6 39.3 125.2 92.6 35.2 47.5 55.4 126.6 329.3 153.3 93.9 47.6 71.6 226.3 74.1 96.5 60.7 81.3 50.8 19.2 66.0 22.9 31.6 31.6 69.6 126.6 32.0 93.7 33.8 1.5 6.3 0.7 10.6 10.8 5.0 16.6 6.0 9.5 15.2 17.1 8.2 8.6 0.2 12.6 12.7 10.8 7.1 7.7 17.5 27.0 26.8 24.0 18.6 24.4 47.3 27.7 35.1 27.6 21.8 34.6 13.2 60.9 97.9 21.5 34.7 22.9 64.0 199.9 16.5 41.8 35.6 27.3 6.1 31.5 129.6 53.3 50.1 99.7 20.6 81.6 7.9 60.3 21.0 95.9 23.3 39.7 31.7 22.3 14.3 83.6 133.7 35.3 51.0 80.5 41.3 77.1 9.7 127.9 61.1 148.0 18.8 58.0 126.1 10.9 30.1 13.2 23.9 22.2 21.4 13.1 91.0 24.3 8.2 20.1 77.9 98.6 38.4 10.9 30.6 118.0 17.3 3.7 123.0 61.1 26.3 12.5 42.0 179.5 128.6 69.5 89.1 217.1 21.1 171.8 35.0 114.8 WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 19.8;Exocrine glandular cells: 17.2;Hofbauer cells: 21.8;Proximal tubular cells: 17.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034216, CAB034219, HPA064649, HPA070916" Supported Enhanced Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "CAB034216: AB_2234159, CAB034219: AB_2130519, HPA064649: AB_2685312, HPA070916: AB_2686322" "unprognostic (1.98e-3)" "unprognostic (3.75e-2)" "unprognostic (8.40e-2)" "unprognostic (3.89e-3)" "unprognostic (2.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.74e-5)" "unprognostic (2.54e-2)" "unprognostic (3.54e-1)" "unprognostic (5.69e-2)" "unprognostic (9.10e-3)" "unprognostic (1.53e-1)" "unprognostic (9.39e-3)" "unprognostic (5.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (2.33e-2)" 18.1 18.6 10.5 18.5 16.9 21.3 19.6 14.9 13.2 17.2 16.5 18.5 18.1 16.2 15.7 16.6 13.3 17.8 16.1 11.1 12.5 22.9 18.5 17.1 19.6 14.7 13.7 15.6 13.0 24.8 9.5 21.2 14.6 17.4 20.1 11.4 14.3 16.1 15.9 13.6 14.7 20.2 14.0 19.3 16.1 9.5 13.8 21.8 23.3 18.5 21.0 21.1 10.3 24.7 40.0 45.4 24.9 30.6 55.3 58.8 16.3 42.0 63.6 43.0 45.8 17.0 42.1 36.1 29.1 54.1 25.3 30.6 40.2 37.7 56.8 47.5 23.1 48.1 26.5 22.8 53.8 14.8 46.6 58.7 25.1 35.5 31.2 33.2 49.9 30.9 28.3 35.6 53.0 87.6 44.3 11.8 23.7 66.7 46.7 29.8 22.4 36.7 33.2 48.5 13.1 26.3 48.8 109.2 39.5 25.8 47.3 25.5 44.7 23.6 51.9 39.4 37.7 31.7 31.2 31.7 62.4 27.5 33.4 10.4 17.0 12.5 13.5 20.9 14.3 9.5 12.8 13.9 19.7 10.6 10.1 14.3 5.8 17.2 29.3 7.2 16.9 13.0 10.5 16.9 14.9 13.2 11.1 12.5 14.7 13.7 14.6 14.0 13.8 24.7 10.9 3.2 19.8 0.0 1.8 0.0 0.0 0.0 0.0 0.0 14.4 9.3 0.0 0.0 5.0 11.0 0.0 13.4 6.9 0.0 5.9 12.2 0.0 9.9 13.5 4.9 0.0 0.0 0.0 17.2 11.0 5.4 0.0 14.8 8.8 11.1 0.0 0.0 21.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 16.2 0.0 0.0 1.9 0.0 0.0 17.2 4.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 3.8 9.6 0.0 0.0 NSMCE2 "C8orf36, FLJ32440, MMS21, NSE2, ZMIZ7" ENSG00000156831 "NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase" Q96MF7 8 125091679-125367120 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Mitosis, Ubl conjugation pathway" Transferase "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Astrocytes: 136.1;Excitatory neurons: 150.1;Inhibitory neurons: 156.8;Microglial cells: 157.4;Oligodendrocyte precursor cells: 139.2;Oligodendrocytes: 386.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051614, HPA065734" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nuclear bodies" "HPA051614: AB_2681551, HPA065734: AB_2685549" "unprognostic (1.14e-3)" "unprognostic (1.29e-1)" "unprognostic (6.56e-2)" "unprognostic (1.22e-3)" "unprognostic (8.65e-2)" "unprognostic (8.89e-3)" "prognostic unfavorable (7.54e-4)" "unprognostic (3.99e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-1)" "unprognostic (1.53e-2)" "unprognostic (1.33e-1)" "unprognostic (3.09e-2)" "unprognostic (1.17e-1)" "unprognostic (7.53e-2)" "unprognostic (2.61e-2)" "unprognostic (6.85e-2)" 19.9 18.1 11.0 14.1 12.8 30.3 23.7 12.4 12.9 17.0 13.4 18.6 12.5 15.8 18.6 17.0 13.4 15.9 23.8 11.2 12.4 18.9 17.8 14.2 21.7 12.2 11.9 19.0 12.8 17.8 11.2 19.6 12.6 13.2 17.5 16.7 16.0 13.9 33.6 15.8 12.3 16.1 11.8 14.5 16.6 15.5 12.7 26.0 18.1 27.2 26.1 20.7 14.7 16.1 43.0 36.3 42.3 26.9 32.7 48.9 20.5 33.5 62.5 58.2 67.0 23.4 39.9 53.2 38.5 32.0 42.9 31.1 33.4 28.2 58.8 60.0 32.4 75.4 20.0 34.1 47.7 22.8 22.1 36.5 38.4 33.6 43.6 38.8 53.2 27.5 44.1 34.2 51.4 74.3 58.9 20.9 9.3 48.4 48.0 33.3 29.4 48.6 35.5 32.1 28.0 29.7 40.1 119.2 56.3 24.9 50.9 25.9 33.3 22.3 62.9 27.8 48.3 45.1 86.6 67.6 35.4 43.4 35.3 12.9 23.9 69.4 22.0 21.7 24.3 25.0 23.1 24.8 24.4 25.5 23.7 25.9 11.3 22.0 23.3 14.2 37.6 24.5 11.0 12.8 12.4 12.9 11.2 12.4 12.2 11.9 12.6 11.8 12.7 16.1 21.8 9.6 13.1 136.1 22.0 23.8 36.3 39.1 21.1 23.8 23.3 24.8 20.1 21.5 26.0 11.0 16.7 34.2 20.3 16.2 27.4 33.1 28.0 26.4 19.7 23.0 13.8 36.2 150.1 42.5 27.8 21.4 13.7 20.7 25.4 24.1 23.2 13.7 44.3 15.2 156.8 17.7 18.3 26.5 24.3 9.9 23.3 24.4 17.8 157.4 29.4 18.4 20.6 139.2 386.0 34.2 19.5 24.5 20.2 28.1 20.6 35.2 23.4 26.4 6.6 20.7 23.4 44.4 31.7 16.0 18.9 46.7 24.6 20.9 19.8 37.6 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430358-125438403 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 365.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 242.7;Distal enterocytes: 281.6;Endometrial stromal cells: 240.1;Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 9.9;neutrophil: 4.7;non-classical monocyte: 3.5;T-reg: 2.8" "Group enriched" "Detected in many" 12 "granulocytes: 9.9;monocytes: 3.5;T-cells: 2.8" "Cell line enhanced" "Detected in many" "HEL: 193.9;U-266/70: 114.2;U-266/84: 123.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA063982: AB_2685165" "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 82.5 25.5 7.5 40.9 9.0 365.5 28.0 12.1 16.2 35.9 7.0 45.1 20.4 25.5 13.6 33.5 15.7 80.2 18.3 8.2 10.1 23.9 139.6 53.7 17.2 9.0 8.4 4.1 43.0 78.9 12.0 28.9 8.7 45.4 51.9 16.3 19.2 7.1 44.0 20.4 32.0 43.2 7.5 22.3 38.0 6.9 11.9 36.0 107.5 19.2 18.0 99.1 5.4 7.6 14.7 16.4 2.2 4.6 4.6 8.8 25.4 9.4 13.2 6.8 2.3 22.1 18.9 26.5 8.5 6.9 40.6 11.0 7.0 9.1 5.8 11.8 34.3 193.9 7.3 43.6 11.6 98.3 17.0 8.5 13.5 27.8 62.8 33.0 20.0 0.3 17.5 81.6 0.9 15.8 9.2 15.3 15.8 35.1 31.6 18.5 3.3 29.2 54.6 55.1 13.7 5.0 22.9 24.6 93.1 14.0 6.4 4.6 10.4 7.3 9.5 7.3 11.7 114.2 123.2 36.6 13.1 0.7 17.7 0.0 0.7 9.9 0.0 1.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 4.7 0.0 3.5 0.3 2.8 0.1 7.5 9.0 12.1 16.2 8.2 10.1 9.0 8.4 8.7 7.5 11.9 7.6 69.6 134.6 168.5 13.7 19.8 100.1 242.7 68.6 77.4 25.5 100.8 71.9 16.6 31.5 67.9 16.5 0.0 12.3 2.8 281.6 11.7 45.3 0.4 96.6 240.1 62.0 112.0 5.3 2.1 24.7 19.1 54.6 58.6 222.5 29.9 0.5 8.2 131.7 35.3 21.9 0.7 129.6 32.6 72.0 59.7 1.7 0.3 85.9 56.9 4.7 27.5 20.1 0.0 4.5 0.2 45.5 130.9 0.4 283.6 139.0 117.4 24.9 39.7 3.8 0.0 36.6 45.1 0.3 2.2 88.2 64.2 30.6 14.8 1.5 106.9 128.7 LRATD2 "BCMP101, FAM84B, NSE2" ENSG00000168672 "LRAT domain containing 2" Q96KN1 8 126552443-126558478 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 43.7" "Cell type enhanced" "Detected in some" "Adipocytes: 20.9;Cardiomyocytes: 6.8;Cytotrophoblasts: 5.4;Endothelial cells: 4.0;Syncytiotrophoblasts: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 78.5;AN3-CA: 104.6;MCF7: 112.1;PC-3: 72.5;SuSa: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050782, HPA062115" Approved Approved Nucleoplasm NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 7: Kidney - Transmembrane transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA050782: AB_2681235, HPA062115: AB_2684686" "unprognostic (2.46e-3)" "unprognostic (6.37e-2)" "unprognostic (7.36e-2)" "prognostic unfavorable (9.71e-4)" "unprognostic (2.75e-3)" "unprognostic (1.54e-1)" "unprognostic (1.79e-1)" "unprognostic (4.52e-2)" "unprognostic (1.32e-1)" "unprognostic (4.49e-2)" "unprognostic (2.42e-3)" "unprognostic (1.07e-2)" "prognostic favorable (1.96e-8)" "unprognostic (2.04e-3)" "unprognostic (1.58e-1)" "unprognostic (1.18e-1)" "prognostic favorable (1.75e-5)" 6.1 2.5 6.1 3.2 7.1 3.0 16.3 7.1 5.2 7.3 25.4 7.6 13.1 7.3 6.8 19.5 8.3 8.1 4.0 5.2 7.1 27.3 8.2 12.0 3.8 8.9 7.5 2.9 16.3 9.2 4.5 7.5 6.9 8.3 8.2 19.1 43.7 6.8 2.5 7.2 7.4 4.6 7.0 3.2 17.6 2.1 5.8 3.2 7.4 5.2 6.3 6.4 5.8 12.6 78.5 9.8 5.8 104.6 0.0 0.0 6.9 1.1 2.7 0.8 1.2 3.0 44.9 0.0 48.5 0.2 8.4 34.3 3.1 14.7 1.3 0.1 63.0 0.0 0.2 0.5 1.4 0.1 1.6 0.6 20.3 0.0 9.0 17.6 6.3 19.7 0.1 0.0 0.5 112.1 2.6 0.0 5.3 65.7 72.5 0.0 2.3 0.8 41.8 32.5 29.7 0.0 2.4 34.9 32.4 162.9 52.0 0.7 0.0 0.3 9.4 0.1 2.0 1.3 0.2 0.1 0.9 5.0 19.6 1.7 0.0 1.5 1.4 0.0 1.4 0.3 1.8 2.7 0.0 0.8 2.0 2.1 0.1 1.1 0.0 0.0 2.6 0.9 6.1 7.1 7.1 5.2 5.2 7.1 8.9 7.5 6.9 7.0 5.8 12.6 20.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 5.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 2.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.9 1.5 0.0 0.0 0.0 POU5F1B "OTF3C, OTF3P1, POU5F1P1" ENSG00000212993 "POU class 5 homeobox 1B" Q06416 8 127322183-127420066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.1" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Distal enterocytes: 3.2;Endometrial ciliated cells: 5.5;Glandular and luminal cells: 10.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.1;EFO-21: 1.5;hTERT-HME1: 3.7;NTERA-2: 1.9" HPA058267 Supported Nucleoplasm NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "HPA058267: AB_2683659" "unprognostic (1.74e-2)" "unprognostic (2.27e-2)" "unprognostic (2.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.65e-1)" "unprognostic (5.85e-2)" "unprognostic (9.31e-4)" "unprognostic (2.21e-3)" "unprognostic (1.13e-1)" "unprognostic (3.25e-1)" "unprognostic (6.56e-2)" "unprognostic (5.11e-2)" "unprognostic (5.60e-10)" "unprognostic (1.21e-1)" "unprognostic (7.05e-3)" "unprognostic (1.37e-1)" "unprognostic (7.33e-3)" 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.7 0.3 0.3 3.1 0.4 0.1 0.5 0.6 0.2 0.5 0.2 0.0 0.5 0.2 0.5 0.2 0.2 0.3 0.3 0.5 0.2 0.2 0.4 0.1 0.2 0.3 0.6 0.5 0.2 1.7 0.3 0.1 0.6 0.1 0.1 0.0 0.2 0.3 0.2 0.2 0.2 0.5 0.0 0.2 0.1 0.2 0.2 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.5 0.0 1.5 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 3.7 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 0.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.2 0.7 0.3 0.5 0.2 0.3 0.5 0.3 0.0 0.2 0.2 1.0 0.0 0.5 0.0 0.2 0.3 0.3 0.3 0.0 0.0 1.0 0.9 0.7 0.0 0.4 0.0 4.2 0.0 0.1 3.2 1.9 1.5 0.3 5.5 0.9 1.4 0.0 0.0 0.0 1.8 0.0 0.4 0.0 10.6 0.0 0.0 0.4 0.1 0.0 1.7 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 2.3 0.0 0.1 0.2 2.7 0.4 0.9 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.6 0.0 0.4 0.0 1.3 0.4 MYC "bHLHe39, c-Myc, MYCC" ENSG00000136997 "MYC proto-oncogene, bHLH transcription factor" P01106 8 127735434-127742951 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 254.6;skin 1: 289.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1013.3;Basal prostatic cells: 1080.5;Basal squamous epithelial cells: 1270.8;Squamous epithelial cells: 768.8;Suprabasal keratinocytes: 1070.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 1069.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000084, CAB010307, HPA055893, HPA066556" Approved Enhanced Nucleoplasm NA NA "Cluster 32: T-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "CAB000084: , CAB010307: AB_631274, HPA055893: AB_2682960, HPA066556: AB_2685691" "unprognostic (1.45e-2)" "unprognostic (4.00e-3)" "unprognostic (3.94e-3)" "unprognostic (2.41e-3)" "unprognostic (8.14e-2)" "unprognostic (3.36e-3)" "unprognostic (5.80e-2)" "unprognostic (4.94e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (7.52e-4)" "unprognostic (5.19e-3)" "unprognostic (9.86e-3)" "prognostic unfavorable (5.49e-8)" "unprognostic (7.85e-2)" "unprognostic (4.66e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (4.96e-5)" 254.6 59.8 2.6 62.3 2.2 53.7 115.8 3.7 3.3 54.4 3.0 57.9 30.6 53.8 3.8 99.5 167.5 83.3 45.5 2.3 6.3 20.0 64.9 47.0 49.4 9.2 5.0 100.0 103.1 7.0 12.3 33.4 6.0 32.7 36.8 0.7 42.2 14.1 50.6 289.1 48.6 54.8 4.5 60.1 70.6 12.5 5.5 47.2 27.0 15.7 39.2 63.2 96.3 4.4 56.8 89.3 9.3 100.9 166.6 209.8 28.4 72.2 31.6 87.5 72.7 137.0 150.2 587.3 86.4 43.0 82.4 122.2 383.8 226.5 67.8 128.9 167.0 370.7 189.5 203.6 150.0 282.0 52.0 138.8 560.4 55.5 490.8 74.8 104.3 217.3 549.8 315.5 49.7 151.9 394.4 616.9 27.4 273.2 204.0 203.7 46.1 1069.6 79.2 61.9 660.7 64.9 32.6 270.7 195.9 17.5 106.4 172.2 120.5 63.4 71.6 49.7 87.2 5.5 8.7 275.9 55.3 286.2 30.8 3.0 39.5 0.7 31.5 36.0 161.5 92.0 114.3 67.4 33.5 71.4 195.2 128.0 4.1 85.5 26.9 1.4 95.6 88.9 2.6 2.2 3.7 3.3 2.3 6.3 9.2 5.0 6.0 4.5 5.5 4.4 218.0 57.7 70.4 0.7 108.0 1013.3 1080.5 278.9 1270.8 0.6 251.3 207.3 10.9 44.3 98.4 12.9 0.0 20.6 20.9 23.0 1.9 78.3 1.0 43.9 224.5 158.0 12.5 189.1 1.6 43.6 61.2 337.9 46.4 72.0 57.0 47.6 141.0 25.8 26.9 0.0 1.1 67.8 97.6 43.7 133.1 3.9 98.8 23.3 168.9 1.0 17.0 1.4 5.2 0.0 0.2 66.5 40.4 67.4 45.7 364.8 4.8 13.3 21.5 0.3 46.0 458.5 349.1 0.6 0.6 768.8 1070.1 5.9 75.0 56.0 117.7 409.4 GSDMC MLZE ENSG00000147697 "Gasdermin C" Q9BYG8 8 129748196-129786624 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 33.1;lymphoid tissue: 12.8;skin 1: 25.5;vagina: 11.4" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 46.5;Basal squamous epithelial cells: 37.5;Squamous epithelial cells: 29.5;Suprabasal keratinocytes: 53.1" "Cancer enhanced" "Detected in many" "cervical cancer: 11.8;head and neck cancer: 19.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 3.7;hTCEpi: 1.8;HUVEC TERT2: 2.0;TIME: 5.8" "Low region specificity" "Detected in many" "HPA023670, HPA024767, HPA026317" Supported Approved Mitochondria NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Mitochondria "HPA023670: AB_1854006, HPA024767: AB_1854007, HPA026317: AB_1854008" "unprognostic (6.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.61e-3)" "unprognostic (4.23e-2)" "unprognostic (2.11e-2)" "unprognostic (4.22e-3)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (8.28e-2)" "unprognostic (7.51e-2)" "unprognostic (4.92e-3)" "unprognostic (5.71e-2)" "unprognostic (2.93e-3)" "unprognostic (1.87e-2)" "unprognostic (1.88e-1)" "unprognostic (8.66e-2)" "unprognostic (1.90e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 4.4 0.0 0.0 0.0 0.0 0.1 33.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 5.4 0.0 0.0 25.5 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.4 11.4 0.1 5.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 2.0 1.0 0.0 46.5 0.9 7.4 37.5 0.0 1.5 0.9 3.6 0.0 9.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.1 0.0 3.9 0.0 0.0 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.1 29.5 53.1 0.0 0.1 0.0 0.0 2.8 CYRIB "BM-009, CYRI, CYRI-B, FAM49B" ENSG00000153310 "CYFIP related Rac1 interactor B" Q9NUQ9 8 129839593-130017129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 198.6" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 117.7;dendritic cells: 66.2;Extravillous trophoblasts: 158.5;Hofbauer cells: 239.7;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009076 Enhanced Approved Nucleoplasm,Cytosol NA NA 1100000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Cytosol "HPA009076: AB_1848402" "unprognostic (4.35e-2)" "unprognostic (5.22e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.80e-2)" "unprognostic (9.61e-3)" "prognostic unfavorable (3.02e-6)" "unprognostic (4.75e-2)" "unprognostic (2.44e-1)" "unprognostic (6.53e-2)" "unprognostic (3.25e-2)" "unprognostic (3.62e-1)" "prognostic unfavorable (3.09e-10)" "unprognostic (3.85e-3)" "unprognostic (1.95e-1)" "unprognostic (2.67e-1)" "unprognostic (2.46e-1)" 41.3 26.3 24.8 97.4 37.9 198.6 25.9 29.9 46.1 13.5 23.1 31.1 30.3 15.9 21.1 29.4 15.3 30.7 18.4 28.3 32.2 22.9 26.5 39.0 119.7 35.9 33.1 11.4 15.9 17.8 17.6 42.0 34.9 14.8 35.8 28.5 18.2 13.1 25.8 19.0 42.3 28.8 35.7 83.6 28.6 29.9 33.6 79.2 28.5 24.3 105.1 50.6 14.1 49.9 167.5 87.7 93.6 52.9 8.2 12.1 124.2 49.4 47.8 67.2 71.4 50.9 111.8 165.5 105.9 32.6 53.3 81.2 78.2 130.6 100.3 349.1 54.5 166.4 44.6 57.7 31.9 109.2 137.1 19.3 60.1 45.3 93.9 54.9 60.2 132.0 121.2 186.3 74.5 74.5 372.0 80.3 79.8 130.4 119.7 160.1 63.3 278.3 138.4 67.4 62.1 81.2 99.2 61.9 152.5 84.1 72.4 139.0 37.5 24.7 158.5 52.8 106.8 61.5 195.7 275.1 38.8 233.5 65.3 350.7 212.5 404.4 161.6 256.2 124.7 122.7 91.2 134.0 280.9 98.7 80.1 132.3 553.9 189.6 232.8 179.8 136.7 306.0 24.8 37.9 29.9 46.1 28.3 32.2 35.9 33.1 34.9 35.7 33.6 49.9 8.4 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 117.7 66.2 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 158.5 6.5 0.0 0.0 0.0 0.0 0.0 0.0 239.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 60.5 8.4 0.0 0.0 0.0 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ADCY8 "AC8, ADCY3, HBAC1" ENSG00000155897 "Adenylate cyclase 8" P40145 8 130780301-131040909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 29.4;epididymis: 22.8" "Group enriched" "Detected in some" 5 "Astrocytes: 151.8;Inhibitory neurons: 250.9;Oligodendrocyte precursor cells: 138.7" "Group enriched" "Detected in some" 5 "glioma: 6.0;ovarian cancer: 1.8;thyroid cancer: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.0;GAMG: 8.2;U-138 MG: 17.6;U-87 MG: 34.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018652, HPA024291" Supported NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "CAB018652: AB_633654, HPA024291: AB_1844597" "unprognostic (5.59e-3)" "unprognostic (3.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.05e-1)" "unprognostic (8.22e-3)" "unprognostic (4.91e-2)" "unprognostic (7.39e-3)" "unprognostic (1.92e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" 0.0 0.0 17.0 0.0 13.4 0.0 0.5 19.7 9.6 0.4 1.7 0.0 0.0 0.0 22.8 0.0 3.9 0.0 0.0 11.9 14.0 0.2 0.0 1.2 0.0 17.2 22.6 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 3.1 1.1 1.4 0.1 2.1 0.0 0.5 25.9 0.0 0.1 0.5 29.4 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.1 1.3 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 17.6 0.4 0.0 0.0 0.0 0.0 0.0 34.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 13.4 19.7 9.6 11.9 14.0 17.2 22.6 15.2 25.9 29.4 23.3 0.0 0.0 1.5 151.8 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 32.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 250.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.1 0.0 138.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 121.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 358.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA022859: AB_1848029, HPA023092: AB_2293240, HPA023402: AB_1848031" "unprognostic (4.79e-2)" "unprognostic (6.54e-2)" "unprognostic (6.42e-2)" "unprognostic (4.37e-3)" "unprognostic (2.77e-1)" "unprognostic (3.44e-2)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-2)" "unprognostic (5.89e-3)" "unprognostic (5.22e-2)" "unprognostic (3.46e-1)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-3)" 21.7 20.8 22.7 20.8 28.6 14.5 20.0 36.4 35.7 28.3 13.2 21.2 23.2 23.4 38.0 27.5 24.2 21.8 33.9 29.5 9.3 29.8 44.5 27.8 25.3 52.7 13.6 19.3 18.6 33.6 12.0 20.4 59.0 26.9 18.4 121.6 17.3 29.3 41.6 21.2 23.5 36.1 7.0 23.5 22.8 22.1 16.1 24.3 37.8 49.1 27.9 26.9 14.0 23.9 55.3 49.0 15.0 12.4 59.9 68.8 29.9 38.6 54.0 31.5 41.3 10.8 40.4 33.8 35.5 87.6 41.8 17.9 23.9 52.9 38.3 78.3 13.1 33.7 22.7 22.0 57.5 13.0 34.1 58.6 29.6 31.2 49.0 52.2 40.2 16.4 18.7 44.3 56.5 36.1 36.5 11.9 8.5 47.3 30.4 14.5 29.4 16.1 38.0 34.1 10.0 34.6 76.9 10.8 30.6 39.3 34.4 22.0 56.3 55.6 50.9 27.4 40.9 31.3 28.8 20.9 41.2 31.0 29.0 12.0 16.8 17.4 16.2 23.3 14.5 12.6 13.0 13.3 17.3 11.2 11.6 12.0 10.1 15.5 40.9 4.0 11.3 15.8 22.7 28.6 36.4 35.7 29.5 9.3 52.7 13.6 59.0 7.0 16.1 23.9 32.6 41.7 42.8 90.8 40.7 21.2 25.3 29.5 25.0 358.8 29.9 16.6 57.4 28.6 37.5 51.5 91.8 22.8 34.1 33.5 21.5 28.7 4.5 25.9 35.1 29.1 11.4 13.3 126.8 30.9 22.2 34.4 29.0 20.7 25.9 19.8 25.0 79.9 44.5 26.9 122.6 18.7 26.4 59.4 25.0 8.0 19.9 52.9 8.8 60.0 53.3 42.3 42.2 77.9 55.6 25.5 36.0 44.4 32.6 55.8 39.9 58.4 27.7 107.5 19.7 32.3 41.4 52.9 30.9 39.1 31.4 37.1 37.3 36.8 17.0 36.7 OC90 PLA2L ENSG00000253117 "Otoconin 90" Q02509 8 132024216-132059382 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted in other tissues" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (1.92e-1)" "unprognostic (2.93e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC100868.1 ENSG00000258417 "Novel protein" 8 132024238-132085655 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "unprognostic (1.82e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HHLA1 PLA2L ENSG00000132297 "HERV-H LTR-associating 1" C9JL84 8 132061486-132111159 "Predicted secreted proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 5 "Alveolar cells type 2: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Secreted - unknown location" NA NA "Cluster 5: NTERA-2 - Transcription" "Cluster 11: Alveolar cells - Smell perception" "unprognostic (5.15e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 2.5 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 KCNQ3 "EBN2, Kv7.3" ENSG00000184156 "Potassium voltage-gated channel subfamily Q member 3" O43525 8 132120859-132481095 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 23.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 501.5;Inhibitory neurons: 485.6;Microglial cells: 502.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 6.6;JURKAT: 3.8;RPMI-8226: 2.8;U-2 OS: 4.3;U-87 MG: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "unprognostic (2.90e-1)" "unprognostic (1.26e-3)" "unprognostic (1.45e-2)" "unprognostic (3.65e-5)" "unprognostic (2.32e-1)" "unprognostic (4.60e-2)" "unprognostic (5.57e-6)" "unprognostic (5.82e-2)" "unprognostic (7.32e-2)" "unprognostic (6.09e-2)" "unprognostic (7.09e-2)" "unprognostic (3.22e-1)" "unprognostic (2.71e-4)" "unprognostic (1.14e-3)" "unprognostic (3.52e-1)" "unprognostic (7.92e-2)" "unprognostic (2.50e-2)" 1.3 1.4 9.9 0.5 21.2 0.0 0.9 0.0 23.7 0.3 0.0 0.4 0.2 0.2 0.1 0.1 0.3 0.3 0.7 9.1 4.7 0.7 0.0 1.9 0.1 4.7 8.1 0.1 0.9 0.2 1.9 0.2 7.4 0.4 0.2 2.5 0.3 0.6 0.0 0.4 0.6 0.5 0.0 0.5 0.1 0.2 16.0 0.5 0.5 0.0 0.2 0.4 0.4 8.7 0.2 0.1 0.0 0.0 0.3 1.0 0.0 0.3 1.1 0.0 0.0 0.0 1.0 0.0 1.2 1.5 2.5 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 1.7 6.6 0.1 0.0 3.8 0.0 0.1 0.9 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 2.8 1.6 0.0 1.3 1.2 0.4 0.0 0.0 0.2 0.0 1.0 0.0 0.0 4.3 0.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 21.2 0.0 23.7 9.1 4.7 4.7 8.1 7.4 0.0 16.0 8.7 0.4 0.0 14.0 84.5 0.2 0.3 0.0 0.0 0.0 6.7 1.3 0.6 4.6 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.6 0.3 4.2 2.7 0.0 0.0 501.5 6.0 0.0 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 485.6 0.7 0.0 0.3 1.6 2.9 0.0 2.1 0.0 502.2 0.6 0.4 0.0 117.1 31.2 1.8 0.0 0.0 0.0 0.1 4.6 1.6 0.8 0.6 0.0 0.0 2.7 0.0 0.5 0.1 0.1 0.0 0.4 0.1 1.2 0.1 LRRC6 "CILD19, LRTP, tilB, TSLRP" ENSG00000129295 "Leucine rich repeat containing 6" Q86X45 8 132570416-132675592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 23.2;testis: 26.2" "Cell type enhanced" "Detected in many" "Early spermatids: 228.5;Endometrial ciliated cells: 101.5;Excitatory neurons: 85.8;Inhibitory neurons: 67.1;Late spermatids: 62.1;Respiratory ciliated cells: 152.7;Spermatocytes: 102.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 9 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.5;RPTEC TERT1: 15.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028058 Approved NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "HPA028058: AB_1853337" "unprognostic (1.53e-1)" "unprognostic (2.77e-1)" "unprognostic (6.91e-3)" "unprognostic (3.56e-2)" "unprognostic (2.50e-2)" "unprognostic (8.04e-3)" "unprognostic (4.06e-2)" "unprognostic (1.20e-1)" "unprognostic (7.39e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" "unprognostic (9.51e-2)" "unprognostic (3.38e-2)" "unprognostic (8.42e-3)" "unprognostic (3.95e-2)" "prognostic unfavorable (5.98e-4)" "unprognostic (4.17e-2)" 3.1 4.3 9.4 1.9 12.2 3.5 2.7 5.6 14.1 4.9 23.2 2.4 0.9 3.1 5.6 1.2 19.5 3.6 2.3 9.7 8.3 11.5 1.5 4.1 0.9 12.8 12.8 3.5 2.8 5.6 8.3 1.7 9.1 2.3 1.5 13.8 2.0 2.2 0.4 1.3 2.6 1.8 10.6 4.0 1.3 26.2 9.1 0.8 7.7 0.6 0.7 2.1 2.2 10.4 0.4 2.2 3.5 0.0 2.9 4.8 7.5 0.3 0.5 1.7 1.5 0.4 8.5 0.0 2.5 3.1 2.4 0.0 0.6 1.1 1.7 0.3 0.0 0.0 0.6 0.1 1.2 0.0 3.8 4.2 2.1 3.9 0.1 4.0 0.8 3.6 0.3 0.0 2.2 2.8 0.0 0.1 5.6 2.6 2.1 0.0 0.1 1.2 15.7 0.0 1.8 2.6 0.3 0.0 0.4 5.4 0.9 0.5 0.0 2.0 7.2 6.3 0.7 0.0 1.0 0.2 5.3 0.4 0.2 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.3 0.0 0.3 9.4 12.2 5.6 14.1 9.7 8.3 12.8 12.8 9.1 10.6 9.1 10.4 2.2 6.4 0.5 24.5 0.5 1.3 3.7 7.7 1.8 2.5 3.3 3.7 2.8 1.5 18.0 9.2 8.4 0.0 0.2 1.7 21.5 6.4 228.5 101.5 7.3 3.1 1.2 0.8 85.8 1.8 0.2 4.4 0.0 7.3 0.0 2.9 4.2 0.5 2.1 1.7 67.1 0.7 8.2 0.8 1.4 62.1 3.7 2.8 0.0 11.2 0.6 7.2 1.0 6.6 5.3 0.7 1.4 4.5 0.0 1.2 2.6 34.7 152.7 13.7 0.0 1.3 4.5 102.6 10.5 1.2 1.1 0.0 0.5 6.0 1.7 1.9 TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.5;heart muscle: 37.1" "Cell type enhanced" "Detected in many" "dendritic cells: 39.9;Kupffer cells: 20.7;Langerhans cells: 25.7;Macrophages: 26.2;monocytes: 25.5;NK-cells: 54.6;T-cells: 35.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 9.7" "Immune cell enhanced" "Detected in all" "neutrophil: 269.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 269.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 12.7;HDLM-2: 54.5;Karpas-707: 11.1;U-937: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria "HPA058401: AB_2683707, HPA070655: AB_2686292" "unprognostic (1.39e-3)" "unprognostic (7.27e-2)" "unprognostic (8.82e-2)" "unprognostic (3.10e-3)" "unprognostic (7.94e-2)" "unprognostic (3.91e-3)" "unprognostic (4.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.63e-1)" "unprognostic (1.62e-1)" "unprognostic (8.83e-2)" "unprognostic (1.90e-2)" "unprognostic (6.29e-3)" "unprognostic (4.39e-2)" "unprognostic (2.73e-1)" 5.6 2.0 1.0 13.1 1.3 33.5 8.5 1.0 9.7 2.5 2.2 11.3 2.2 1.3 1.1 2.8 1.9 5.5 37.1 1.1 1.8 2.6 3.9 8.2 13.2 1.6 1.3 1.0 2.4 0.7 1.1 1.8 2.1 2.0 3.4 0.5 5.7 2.2 1.6 1.1 7.3 3.6 1.1 18.4 2.8 1.0 2.4 19.2 2.0 4.6 10.6 4.6 1.9 1.6 0.4 0.0 4.9 0.0 0.0 0.0 0.0 1.3 12.7 0.5 0.9 0.0 0.0 0.1 0.6 4.1 0.1 0.0 0.0 0.3 1.5 54.5 0.0 0.0 0.0 0.0 0.3 3.6 0.0 0.1 0.0 0.1 2.0 1.4 1.0 6.7 0.0 11.1 2.4 0.0 2.9 2.2 1.2 0.0 0.4 0.1 1.8 0.8 4.8 0.1 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 2.1 0.5 0.9 1.2 5.7 0.1 2.9 0.0 9.0 31.6 3.7 61.9 55.9 101.6 31.3 16.1 57.9 6.6 22.8 22.2 33.7 4.7 33.9 25.1 269.0 12.9 14.7 1.1 3.0 39.0 1.0 1.3 1.0 9.7 1.1 1.8 1.6 1.3 2.1 1.1 2.4 1.6 0.5 0.0 3.0 0.0 6.9 0.9 1.0 2.5 0.6 0.0 4.2 2.7 15.9 0.0 5.5 0.0 0.0 0.0 39.9 0.1 0.0 0.0 6.5 0.1 0.3 1.5 0.0 8.8 0.5 0.0 0.0 4.1 1.1 0.2 1.3 0.0 3.3 0.2 3.2 0.0 1.3 0.2 0.0 20.7 25.7 5.1 0.0 26.2 5.4 17.8 25.5 1.9 54.6 0.0 0.1 0.1 0.0 0.0 11.3 0.1 0.0 0.4 2.9 0.0 0.0 3.7 0.8 0.0 0.6 0.4 0.3 0.3 35.9 0.1 0.0 4.5 PHF20L1 "CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B" ENSG00000129292 "PHD finger protein 20 like 1" A8MW92 8 132775358-132848807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025060, HPA028417" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA025060: AB_10599822, HPA028417: AB_10602278" "unprognostic (9.12e-3)" "unprognostic (2.29e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-3)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (2.79e-2)" "unprognostic (7.53e-2)" "unprognostic (9.66e-2)" "unprognostic (1.24e-2)" "unprognostic (8.85e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.83e-2)" 12.1 14.0 8.0 13.5 9.6 24.9 10.9 10.4 11.3 11.6 9.9 9.2 9.4 11.4 10.0 11.6 7.9 10.7 17.5 8.0 6.4 10.7 13.4 10.3 11.8 6.5 6.7 11.3 8.9 15.7 8.7 12.4 6.7 9.9 10.1 12.5 9.6 8.0 16.7 7.7 9.9 11.5 5.7 11.5 9.3 13.5 7.2 25.6 22.7 18.5 12.4 12.8 8.9 9.8 20.9 20.6 33.1 19.1 25.3 29.9 11.9 30.1 23.4 20.2 19.7 11.5 14.0 23.8 25.6 30.3 17.4 12.0 22.5 16.0 24.9 40.4 16.1 25.5 24.3 8.2 26.6 20.7 17.6 22.5 19.4 21.1 31.1 19.5 22.6 37.2 32.1 36.4 30.4 21.0 67.6 9.2 14.7 23.8 27.1 32.6 22.1 20.6 16.5 17.8 81.4 23.8 19.1 13.5 24.5 13.8 26.5 23.0 29.6 32.6 25.9 21.5 29.1 21.5 29.9 30.3 28.8 35.8 29.6 3.5 3.8 7.0 2.1 2.4 2.1 2.1 1.9 2.5 3.6 2.2 2.8 2.2 12.6 3.0 3.6 2.9 2.5 1.5 8.0 9.6 10.4 11.3 8.0 6.4 6.5 6.7 6.7 5.7 7.2 9.8 65.9 25.6 51.6 74.4 51.1 33.6 52.6 48.2 40.9 55.7 40.5 38.0 88.5 25.8 57.2 36.8 43.8 29.7 92.9 35.1 23.5 37.3 81.2 39.8 73.4 55.2 43.7 37.9 133.9 31.3 32.0 51.6 41.8 48.9 60.2 60.1 36.0 33.4 36.6 53.8 192.2 29.0 44.7 39.6 49.3 49.5 40.0 84.2 23.2 83.4 67.5 50.9 78.2 104.5 117.5 40.6 26.4 42.9 66.6 40.4 41.5 25.7 30.8 54.1 46.0 68.1 58.9 115.1 45.9 44.9 36.2 45.0 65.8 61.4 30.9 66.7 TG "AITD3, TGN" ENSG00000042832 Thyroglobulin P01266 8 132866958-133134903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Thyroid hormones biosynthesis" "Hormone, Thyroid hormone" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 685 "thyroid gland: 9329.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 5.5;Cardiomyocytes: 3.0;Early spermatids: 2.3;Late spermatids: 2.2;Microglial cells: 1.9;Proximal tubular cells: 4.0" "Cancer enriched" "Detected in some" 1672 "thyroid cancer: 3072.8" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 2.1;HSkMC: 2.4;Karpas-707: 5.6;PC-3: 2.8;U-266/70: 2.0;U-266/84: 1.8" "Region enriched" "Detected in single" 5 "cerebellum: 1.1" "Low region specificity" "Detected in some" "CAB000077, HPA002740, CAB056155" Enhanced "Secreted in other tissues" NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "CAB000077: , CAB056155: AB_2665573, HPA002740: AB_1080277" "unprognostic (1.18e-1)" "unprognostic (6.86e-2)" "unprognostic (7.40e-4)" "unprognostic (1.20e-2)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (7.38e-2)" "unprognostic (4.96e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-2)" "unprognostic (3.68e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-1)" "unprognostic (5.11e-2)" "unprognostic (3.64e-2)" 1.6 3.2 3.0 0.5 0.4 7.8 1.4 0.2 1.9 1.2 1.5 1.8 0.0 1.8 1.0 2.0 0.4 8.6 13.6 1.7 0.2 2.9 3.6 4.2 12.0 0.4 0.5 1.2 8.0 2.7 1.2 0.2 0.5 3.6 0.1 0.1 3.9 1.8 2.8 6.3 1.7 0.1 0.2 1.9 2.2 2.9 0.5 0.4 9329.0 0.0 0.6 0.6 1.7 0.5 0.0 0.0 0.0 0.0 0.5 0.7 0.3 0.0 1.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.4 1.7 0.6 0.0 0.5 0.0 0.7 0.0 5.6 0.1 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.2 0.1 1.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.3 0.0 2.0 1.8 0.0 0.1 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.3 0.1 0.1 3.0 0.4 0.2 1.9 1.7 0.2 0.4 0.5 0.5 0.2 0.5 0.5 0.3 0.0 0.6 0.3 0.2 0.0 5.5 0.1 0.0 0.0 0.1 0.1 3.0 0.0 1.3 0.0 0.0 0.0 0.2 0.1 0.0 0.0 2.3 0.3 0.1 0.4 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.2 0.4 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.0 2.2 0.0 0.1 0.0 1.9 0.7 0.3 0.0 0.5 0.1 0.1 0.0 0.4 0.1 0.5 0.0 4.0 0.0 0.0 0.0 0.3 0.3 0.8 0.3 0.0 0.6 0.0 0.2 1.1 0.0 1.2 SLA "hSLAP, SLA1, SLAP, SLAP-1" ENSG00000155926 "Src like adaptor" Q13239 8 133036728-133102912 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 97.4;lymphoid tissue: 156.6" "Cell type enhanced" "Detected in many" "dendritic cells: 224.2;Hofbauer cells: 67.4;Kupffer cells: 199.4;Macrophages: 154.2;NK-cells: 109.2;Plasma cells: 83.0;T-cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HMC-1: 47.9;JURKAT: 201.5;Karpas-707: 129.2;MOLT-4: 35.8;U-266/84: 76.1;U-937: 55.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012296, HPA074192" Enhanced Approved "Nuclear membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Cytosol" "HPA012296: AB_1856946, HPA074192: AB_2686673" "unprognostic (1.19e-2)" "unprognostic (6.29e-3)" "unprognostic (2.73e-3)" "unprognostic (6.07e-3)" "unprognostic (1.66e-2)" "unprognostic (1.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (9.25e-2)" "unprognostic (3.03e-2)" "unprognostic (2.73e-1)" "unprognostic (2.80e-3)" "unprognostic (2.66e-1)" "unprognostic (3.05e-2)" "unprognostic (8.60e-2)" "unprognostic (1.65e-1)" 25.2 13.1 9.5 82.9 6.4 97.4 9.5 6.1 11.5 11.1 8.2 10.8 7.9 5.2 2.9 9.4 7.0 20.9 5.2 8.2 9.1 6.4 16.9 25.9 78.6 12.0 8.4 3.0 5.8 3.1 3.1 15.2 10.3 5.2 8.4 1.3 4.6 3.6 1.5 4.0 20.7 12.5 9.7 70.3 12.5 1.4 16.9 156.6 27.6 4.4 71.0 22.0 4.2 14.6 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.9 0.1 2.3 0.0 0.0 0.0 6.3 47.9 0.8 0.0 0.6 0.0 0.2 0.0 201.5 0.1 129.2 0.0 0.0 35.8 9.3 0.0 0.0 0.0 0.2 0.3 7.8 0.0 0.0 0.0 1.0 0.0 0.1 0.1 3.1 0.0 15.3 0.0 0.1 0.3 0.2 0.1 6.9 76.1 0.0 0.6 55.6 0.0 0.7 110.2 203.6 87.6 123.1 110.1 41.0 79.7 88.2 79.8 48.3 75.3 77.4 262.3 132.6 148.4 6.3 124.4 158.9 9.5 6.4 6.1 11.5 8.2 9.1 12.0 8.4 10.3 9.7 16.9 14.6 2.4 9.6 19.1 0.7 36.6 2.2 0.3 0.0 0.0 9.7 0.9 1.3 3.3 1.5 10.5 0.0 0.0 0.4 224.2 0.2 0.0 0.2 0.2 0.7 0.7 5.9 0.0 13.2 1.0 0.0 1.2 4.5 3.6 0.5 37.2 1.7 8.9 2.9 67.4 0.0 1.3 0.5 0.0 199.4 15.0 1.0 0.3 154.2 5.4 14.0 36.7 0.1 109.2 0.0 0.1 0.0 0.0 0.0 83.0 0.1 0.0 0.3 5.1 0.3 6.6 1.4 1.9 0.0 0.1 0.3 2.7 0.1 160.0 0.1 0.1 0.2 CCN4 "WISP-1, WISP1, WISP1-OT1, WISP1-UT1" ENSG00000104415 "Cellular communication network factor 4" O95388 8 133191039-133231690 "Cancer-related genes, Predicted secreted proteins" "Cell adhesion, Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HSkMC: 110.5;hTEC/SVTERT24-B: 64.5;U-2197: 61.9" "Region enriched" "Detected in some" 6 "olfactory bulb: 9.8" "Low region specificity" "Detected in many" "HPA007121, CAB012205" Uncertain Approved Cytosol "Secreted to extracellular matrix" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "CAB012205: , HPA007121: AB_1858844" "unprognostic (7.77e-2)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (3.20e-1)" "unprognostic (7.72e-2)" "unprognostic (6.63e-2)" "unprognostic (8.61e-3)" "unprognostic (3.26e-2)" "unprognostic (2.07e-3)" "unprognostic (1.41e-3)" "unprognostic (3.01e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (7.52e-3)" "unprognostic (2.55e-3)" "unprognostic (6.03e-2)" "unprognostic (5.67e-3)" 4.4 10.3 1.3 7.6 2.6 0.0 0.9 0.5 1.4 10.9 0.9 3.9 1.2 14.0 0.9 0.9 5.9 7.8 3.7 1.3 0.4 15.8 2.0 8.3 3.0 0.7 0.6 6.0 0.8 9.2 2.3 2.8 0.7 3.3 0.8 0.0 1.1 1.4 0.4 1.4 2.3 13.6 0.6 2.2 2.8 1.2 0.9 0.2 1.1 0.2 3.9 6.0 3.6 0.8 0.0 0.5 0.0 0.0 7.6 4.2 0.1 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.6 0.0 0.0 110.5 0.0 64.5 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.6 0.0 0.0 0.0 14.8 0.8 61.9 0.0 0.0 0.0 0.0 12.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.6 0.5 1.4 1.3 0.4 0.7 0.6 0.7 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 NDRG1 "CAP43, DRG1, NDR1, RTP, TDD5" ENSG00000104419 "N-myc downstream regulated 1" Q92597 8 133237175-133302022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 613.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 571.9;Distal enterocytes: 405.4;Horizontal cells: 588.9;Suprabasal keratinocytes: 667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 606.9;hTERT-HME1: 1226.9;U-87 MG: 772.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006881 Approved Supported Microtubules,Cytosol NA NA 200000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" Cytosol Microtubules "HPA006881: AB_1078392" "unprognostic (6.96e-3)" "unprognostic (3.31e-3)" "unprognostic (8.53e-2)" "unprognostic (1.41e-3)" "unprognostic (1.54e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.47e-4)" "unprognostic (3.04e-3)" "unprognostic (5.33e-2)" "unprognostic (4.29e-2)" "unprognostic (9.09e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (4.13e-4)" "unprognostic (7.27e-2)" "unprognostic (1.91e-1)" "unprognostic (2.47e-3)" "unprognostic (4.28e-2)" 161.2 72.9 299.1 55.9 523.6 130.0 107.6 413.5 300.2 169.4 132.8 130.0 242.2 92.9 34.3 343.1 106.4 87.8 99.8 254.5 316.6 192.4 49.6 116.6 38.7 523.2 500.0 126.1 52.8 69.1 82.2 110.8 476.8 354.3 77.8 86.0 130.8 60.0 28.2 262.6 258.1 61.9 333.7 39.4 154.0 28.1 423.1 55.1 80.5 44.6 88.1 105.5 273.8 613.9 191.6 24.0 1.7 0.8 116.3 86.8 26.0 13.7 103.0 9.8 52.5 12.5 27.6 1.5 133.0 58.0 21.9 62.4 1.7 316.8 18.0 13.3 226.8 1.9 55.6 14.7 46.3 7.0 4.6 79.2 606.9 51.2 1226.9 124.2 45.2 27.9 2.0 138.3 17.2 11.0 19.1 20.8 3.0 69.8 155.8 1.7 19.4 86.2 29.7 28.0 13.8 13.0 31.0 312.1 73.3 48.6 1.3 20.0 58.5 84.4 43.6 40.7 10.4 96.3 280.3 0.8 772.5 69.5 161.5 10.9 4.3 0.0 5.8 3.4 9.1 1.6 5.3 6.9 6.0 1.4 3.9 3.1 4.0 1.5 4.2 13.0 8.1 3.7 299.1 523.6 413.5 300.2 254.5 316.6 523.2 500.0 476.8 333.7 423.1 613.9 123.0 144.2 47.4 14.4 23.6 571.9 141.3 207.3 42.1 68.8 28.6 31.2 20.6 80.1 102.9 187.6 2.1 12.8 68.1 405.4 33.2 33.2 5.3 57.4 59.0 217.7 22.1 17.4 7.7 13.7 138.2 90.5 151.4 167.7 22.2 41.0 112.8 64.0 16.5 588.9 5.7 140.9 83.4 31.1 109.5 5.9 49.0 42.7 101.4 28.1 25.7 81.2 14.4 20.6 136.2 62.9 155.9 44.0 23.5 264.3 402.5 87.5 38.7 40.3 46.0 65.2 44.3 1.2 7.1 113.0 667.4 43.4 45.7 32.6 124.7 280.8 ST3GAL1 "SIAT4A, SIATFL, ST3GalA.1, ST3O" ENSG00000008513 "ST3 beta-galactoside alpha-2,3-sialyltransferase 1" Q11201 8 133454848-133571940 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 75.9;PC-3: 131.8;RT4: 102.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040466 Approved "Intracellular and membrane" NA NA 860000 "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "HPA040466: AB_10805712" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (6.66e-2)" "unprognostic (1.83e-3)" "unprognostic (5.53e-3)" "unprognostic (4.43e-2)" "unprognostic (4.79e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "unprognostic (3.55e-3)" "unprognostic (1.10e-1)" "unprognostic (1.83e-3)" "unprognostic (1.67e-2)" "unprognostic (3.29e-2)" "unprognostic (8.64e-3)" "unprognostic (2.95e-2)" 25.7 22.5 8.8 22.8 8.6 22.6 12.2 5.3 9.4 11.4 12.3 6.5 3.6 11.6 12.7 14.0 15.5 19.0 53.1 9.6 6.3 44.5 67.7 19.2 23.1 7.9 11.2 13.3 15.4 10.9 9.9 13.8 6.9 8.0 5.5 10.0 24.9 10.2 43.8 5.9 9.9 10.6 7.2 21.2 16.1 4.3 7.4 17.4 66.1 49.3 21.6 34.4 10.9 7.2 14.0 6.6 3.0 8.3 28.6 15.0 14.4 15.4 35.5 5.7 4.4 13.3 15.1 3.3 10.3 28.2 2.7 4.2 9.4 11.3 4.9 37.6 1.7 28.4 22.5 25.4 22.0 5.9 22.1 17.8 5.7 19.5 11.7 27.2 26.4 7.5 0.5 42.5 4.4 14.9 8.4 8.0 2.1 75.9 131.8 9.9 3.7 24.3 2.7 102.2 0.7 2.0 6.8 23.3 6.9 15.4 4.3 8.1 26.3 18.3 28.5 15.7 6.9 53.0 39.3 3.6 41.7 19.8 18.5 47.8 8.8 41.7 24.1 8.1 22.9 22.7 25.2 28.3 5.3 38.6 34.4 32.4 16.1 43.2 20.4 12.6 17.2 18.9 8.8 8.6 5.3 9.4 9.6 6.3 7.9 11.2 6.9 7.2 7.4 7.2 29.4 6.4 56.8 38.2 68.4 5.7 14.4 14.8 21.1 13.4 13.7 8.4 63.2 12.8 22.2 1.8 2.1 9.7 65.5 4.6 5.9 41.3 3.4 8.9 29.2 44.3 0.0 38.5 36.7 25.4 53.5 47.8 10.7 28.1 8.8 12.1 37.9 159.8 37.8 60.6 34.6 0.6 16.2 52.5 29.0 2.1 36.7 48.8 14.2 49.6 59.8 11.5 47.4 5.0 2.4 39.4 0.0 71.8 29.1 10.9 0.0 48.5 6.5 23.3 13.1 28.1 23.6 0.2 2.8 30.0 3.4 26.4 79.9 6.5 0.3 43.6 ZFAT "KIAA1485, ZFAT1, ZNF406" ENSG00000066827 "Zinc finger and AT-hook domain containing" Q9P243 8 134477788-134713049 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 31.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 74.5;dendritic cells: 35.6;Early spermatids: 49.3;Late spermatids: 53.0;Syncytiotrophoblasts: 126.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 24 "plasmacytoid DC: 34.5" "Lineage enriched" "Detected in many" 24 "dendritic cells: 34.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020989, HPA063592" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 2: Karpas-707 - Immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nuclear bodies" Nucleoplasm "HPA020989: AB_2670552, HPA063592: AB_2685051" "unprognostic (2.00e-1)" "unprognostic (1.45e-1)" "unprognostic (4.62e-3)" "unprognostic (5.91e-3)" "unprognostic (2.45e-1)" "unprognostic (5.12e-2)" "unprognostic (1.31e-4)" "unprognostic (6.27e-2)" "unprognostic (2.68e-2)" "unprognostic (1.28e-1)" "unprognostic (2.43e-2)" "unprognostic (1.13e-1)" "unprognostic (1.90e-2)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (1.33e-1)" 2.2 1.4 0.8 2.8 0.9 1.2 2.1 0.5 1.4 1.8 1.7 4.7 2.3 2.5 2.0 2.6 2.0 1.2 2.2 1.0 0.9 9.7 1.5 2.2 3.7 1.3 0.6 2.1 2.3 2.7 1.5 31.1 0.8 2.2 1.7 2.7 1.8 2.1 7.5 1.9 2.1 2.6 0.5 2.5 1.9 2.3 0.7 3.2 1.6 4.3 2.9 2.8 1.8 0.7 4.1 6.5 2.3 2.9 4.4 4.3 2.1 4.4 3.8 3.9 4.0 4.5 5.2 4.7 3.8 4.6 2.3 3.2 4.7 5.6 5.1 3.9 6.0 8.7 5.7 3.3 3.4 4.9 4.3 3.5 2.8 4.3 5.7 3.6 4.9 1.7 3.4 8.4 3.4 5.6 5.1 0.8 3.2 4.2 3.9 3.1 3.0 2.0 3.8 6.2 2.8 2.1 4.5 3.4 3.7 2.6 2.8 4.6 5.4 2.3 3.4 3.3 5.0 3.0 4.4 4.5 2.8 3.6 4.9 1.1 0.6 1.4 0.4 0.8 0.4 0.9 0.4 0.7 0.5 1.1 0.6 0.4 1.0 0.1 0.5 34.5 0.3 0.9 0.8 0.9 0.5 1.4 1.0 0.9 1.3 0.6 0.8 0.5 0.7 0.7 3.5 3.2 3.3 14.4 7.0 1.5 1.2 1.0 1.8 5.3 4.0 1.4 2.0 1.5 3.1 1.8 4.2 74.5 35.6 1.5 0.0 2.1 49.3 2.6 5.0 2.8 0.0 0.8 24.4 1.5 17.2 2.7 3.6 3.1 2.5 2.9 0.7 1.4 8.4 1.7 18.9 1.4 0.0 3.8 2.1 53.0 3.4 4.2 8.8 14.0 3.5 2.1 4.1 9.5 12.6 3.3 0.5 2.6 17.0 1.6 1.1 12.2 1.1 6.0 0.0 3.7 2.5 2.9 5.5 1.9 1.7 126.7 3.6 3.2 1.3 1.5 KHDRBS3 "Etle, etoile, SALP, SLM-2, SLM2, T-STAR" ENSG00000131773 "KH RNA binding domain containing, signal transduction associated 3" O75525 8 135457456-135656722 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 157.7" "Cell type enhanced" "Detected in many" "Early spermatids: 364.5;Excitatory neurons: 828.6;Inhibitory neurons: 190.8;Microglial cells: 227.7;Oligodendrocyte precursor cells: 578.6;Spermatocytes: 276.1" "Cancer enhanced" "Detected in all" "glioma: 9.0" "Group enriched" "Detected in many" 5 "amygdala: 21.4;basal ganglia: 27.9;cerebral cortex: 50.9;hippocampal formation: 29.8;white matter: 41.1" "Immune cell enriched" "Detected in single" 13 "eosinophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Cell line enhanced" "Detected in many" "REH: 87.8;RPTEC TERT1: 76.0;WM-115: 85.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000275, HPA000500, HPA000981" Enhanced Supported Nucleoplasm NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "HPA000275: AB_1079183, HPA000500: AB_1079184, HPA000981: AB_2666164" "unprognostic (1.36e-1)" "unprognostic (1.61e-1)" "unprognostic (1.98e-1)" "unprognostic (6.55e-3)" "unprognostic (2.75e-1)" "unprognostic (2.43e-1)" "unprognostic (1.31e-3)" "unprognostic (9.36e-2)" "unprognostic (2.00e-2)" "unprognostic (2.66e-1)" "unprognostic (1.91e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.16e-6)" "unprognostic (6.63e-2)" "unprognostic (7.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.33e-3)" 16.8 16.4 21.4 5.6 27.9 2.6 11.5 0.0 50.9 17.0 0.0 12.5 4.1 6.8 22.8 6.2 6.5 11.5 10.3 29.8 0.6 19.3 12.3 8.8 3.0 7.5 1.4 9.3 9.2 7.6 6.8 2.0 0.4 8.4 8.9 21.1 11.0 12.3 32.6 6.4 5.9 8.7 0.0 2.8 6.9 157.7 5.7 9.2 5.6 31.2 4.2 10.6 9.0 41.1 0.5 1.8 30.9 1.7 6.5 12.0 12.4 20.7 28.6 19.2 9.8 11.1 4.4 0.1 10.9 19.8 0.3 2.7 19.5 20.9 26.0 4.4 33.6 0.1 11.2 22.9 5.0 5.8 69.8 2.6 2.8 10.5 16.1 23.2 15.9 36.7 2.6 51.0 34.5 7.5 2.2 1.2 6.3 16.9 34.0 87.8 42.0 22.6 76.0 0.6 39.5 33.4 1.5 4.4 22.6 19.4 1.4 1.8 1.3 23.6 40.7 0.4 45.2 17.9 0.0 0.1 14.3 0.0 85.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 27.9 0.0 50.9 29.8 0.6 7.5 1.4 0.4 0.0 5.7 41.1 15.4 28.9 5.3 20.2 3.1 15.0 14.7 2.3 2.8 160.9 23.8 10.8 12.3 2.8 4.8 7.3 0.0 0.6 0.6 7.0 25.4 14.6 364.5 24.2 21.1 13.7 23.4 0.8 828.6 22.9 1.2 37.2 2.0 40.7 4.5 4.0 5.0 21.8 0.8 6.7 190.8 8.7 10.2 3.5 10.9 142.4 16.1 5.2 14.2 227.7 1.6 7.0 0.0 578.6 34.9 19.8 2.5 8.6 1.1 19.3 2.1 29.0 2.9 16.1 0.0 57.9 34.5 276.1 33.1 3.4 9.2 1.4 2.1 12.7 6.6 12.6 FAM135B C8ORFK32 ENSG00000147724 "Family with sequence similarity 135 member B" Q49AJ0 8 138130023-138497261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.7;retina: 9.1;testis: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 64.3;Early spermatids: 157.1;Excitatory neurons: 229.3;Inhibitory neurons: 267.0" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 11 "RH-30: 8.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023911, HPA023950, HPA024815" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane" Nucleoplasm "HPA023911: AB_1845791, HPA023950: AB_1845792, HPA024815: AB_10601376" "unprognostic (3.78e-1)" "unprognostic (4.80e-1)" "unprognostic (1.71e-2)" "unprognostic (6.64e-2)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (1.42e-1)" "unprognostic (8.26e-2)" "unprognostic (8.36e-3)" "unprognostic (4.54e-2)" "unprognostic (6.85e-4)" "unprognostic (9.92e-3)" "unprognostic (9.82e-3)" "unprognostic (4.47e-1)" "unprognostic (2.70e-2)" "unprognostic (3.51e-2)" "unprognostic (1.30e-1)" 0.1 2.6 4.8 0.1 4.8 0.0 0.0 6.1 10.7 0.0 0.0 0.8 0.3 0.0 0.1 0.0 0.0 0.0 0.1 6.8 1.1 0.3 0.0 0.0 0.0 5.0 3.0 0.0 0.4 0.0 1.3 0.0 5.1 0.2 0.6 9.1 0.0 0.2 0.0 0.0 0.3 0.0 1.8 0.0 0.6 3.8 3.4 0.1 0.0 0.3 0.0 0.4 0.1 5.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 8.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.8 6.1 10.7 6.8 1.1 5.0 3.0 5.1 1.8 3.4 5.7 0.0 0.0 0.0 64.3 0.0 0.0 0.0 0.0 0.0 32.2 0.0 0.0 1.4 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 157.1 0.0 0.0 0.1 1.8 0.0 229.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 267.0 0.0 0.0 0.0 0.4 32.7 1.5 0.1 0.0 8.4 0.0 2.9 0.0 34.2 17.5 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.3 0.1 1.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 39.6;Excitatory neurons: 13.0;Late spermatids: 33.7;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 29.5;RT4: 12.2;SCLC-21H: 8.1;U-2 OS: 6.8" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 7.6 0.6 0.6 1.0 0.0 0.0 2.9 0.5 0.8 0.4 1.0 0.3 1.9 0.2 0.1 0.4 0.3 0.2 0.3 1.4 1.9 0.0 0.0 0.5 2.9 1.2 0.2 0.1 1.4 44.0 0.0 0.6 3.0 0.1 5.2 0.9 2.4 0.7 0.0 0.4 1.6 4.3 0.2 2.2 1.1 2.0 2.1 0.2 1.1 1.2 0.9 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.2 8.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.9 0.5 0.3 1.4 2.9 1.2 0.6 4.3 2.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 3.7 2.5 0.0 0.3 0.2 0.3 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 39.6 0.1 0.2 0.8 0.0 0.0 13.0 0.2 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.0 5.9 0.0 0.8 0.0 8.2 0.0 0.0 33.7 0.3 0.3 0.0 1.0 0.6 25.5 0.0 0.5 0.3 3.0 0.0 0.0 0.0 4.8 0.0 0.1 0.2 1.6 0.0 0.1 0.3 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.1 1.9 KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 16.0;Inhibitory neurons: 8.0;Late spermatids: 9.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 4 "cerebellum: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA075842: " "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.96e-8)" "unprognostic (1.91e-1)" "unprognostic (8.17e-3)" "unprognostic (2.19e-3)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (5.12e-6)" "unprognostic (2.94e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" "unprognostic (1.76e-1)" 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.8 1.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.9 0.2 0.1 0.8 0.3 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.3 2.1 0.0 0.0 0.0 0.0 0.0 16.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 CHRAC1 "CHRAC15, YCL1" ENSG00000104472 "Chromatin accessibility complex subunit 1" Q9NRG0 8 140511311-140517154 "Predicted intracellular proteins" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059008 Approved Nucleoplasm NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "HPA059008: AB_2683878" "unprognostic (6.34e-2)" "unprognostic (7.32e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.29e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (4.88e-5)" "unprognostic (8.79e-3)" "unprognostic (1.86e-1)" "prognostic favorable (9.72e-4)" "prognostic unfavorable (5.43e-4)" "unprognostic (4.19e-1)" "unprognostic (6.22e-3)" "unprognostic (7.61e-2)" "unprognostic (1.01e-1)" "unprognostic (6.92e-2)" "unprognostic (1.49e-1)" 15.0 11.6 11.0 16.9 14.4 28.1 12.5 11.0 12.1 12.7 7.3 16.9 16.0 15.1 11.7 21.5 13.2 16.6 15.9 9.5 9.9 16.1 14.5 14.8 24.0 14.4 13.1 13.5 18.2 16.4 8.8 15.0 12.7 11.6 16.1 4.6 13.0 11.6 27.9 19.7 18.2 18.1 10.6 12.5 15.6 14.5 12.0 21.4 20.9 25.3 26.2 17.7 11.7 18.0 53.3 25.2 23.1 22.0 22.6 38.1 17.8 22.2 32.2 31.8 38.1 32.5 37.1 54.6 32.2 27.4 25.1 32.3 28.0 22.6 43.6 42.5 30.2 77.5 33.1 37.0 21.4 26.2 39.4 19.2 32.5 23.6 45.3 17.1 30.9 33.1 58.3 50.4 28.4 61.6 91.6 27.9 17.2 46.5 43.6 54.4 24.7 43.5 32.0 21.8 31.7 26.3 31.1 20.9 39.5 12.6 40.4 29.3 29.4 37.4 65.1 46.5 47.8 24.2 34.0 66.3 45.0 61.1 29.6 10.6 20.2 25.4 18.2 26.5 17.5 20.4 15.6 17.7 22.4 24.1 16.0 13.9 24.3 20.3 30.2 22.8 15.6 16.1 11.0 14.4 11.0 12.1 9.5 9.9 14.4 13.1 12.7 10.6 12.0 18.0 32.3 16.0 29.9 4.2 45.6 38.4 39.2 28.5 29.0 7.4 26.3 18.0 14.7 20.0 25.9 14.7 2.1 24.9 45.0 23.4 43.0 27.4 20.2 25.6 31.4 29.6 21.6 28.8 2.4 36.0 49.3 27.4 19.4 44.8 32.4 13.3 31.8 22.4 25.2 6.7 2.5 23.6 24.4 30.8 51.4 31.7 29.2 37.1 19.6 6.5 43.8 26.9 43.3 4.0 14.9 38.2 20.6 25.2 26.4 35.2 29.0 33.8 13.9 11.7 72.3 34.9 31.1 75.5 58.3 34.5 48.6 24.1 42.4 15.8 22.3 35.9 AGO2 "CASC7, EIF2C2, hAGO2, LINC00980, Q10" ENSG00000123908 "Argonaute RISC catalytic component 2" Q9UKV8 8 140520156-140635633 "Enzymes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Transcription, Transcription regulation, Translation regulation" "Endonuclease, Hydrolase, Nuclease, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019309, HPA067849" Approved Supported "Cytosol,Cytoplasmic bodies" NA NA 65000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cytoplasmic bodies" Cytosol "CAB019309: , HPA067849: " "unprognostic (2.75e-2)" "unprognostic (1.79e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (2.46e-1)" "unprognostic (2.15e-1)" "unprognostic (1.49e-3)" "unprognostic (8.86e-2)" "unprognostic (2.21e-1)" "unprognostic (8.50e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (1.32e-1)" "unprognostic (2.77e-1)" "unprognostic (1.32e-1)" "unprognostic (3.02e-1)" 7.8 4.1 6.9 6.2 11.5 11.3 5.9 12.4 9.2 6.9 2.4 8.6 3.2 7.7 5.9 6.3 8.3 5.1 7.3 5.7 11.4 5.9 3.8 9.1 6.1 14.0 10.1 9.5 5.0 7.0 8.0 5.8 11.3 5.8 4.0 6.8 4.8 4.6 17.5 8.5 6.2 5.2 5.9 5.2 6.6 3.3 10.8 7.6 6.3 9.1 5.4 6.6 6.7 19.2 18.9 15.2 15.3 17.6 9.9 11.5 12.9 11.6 8.4 5.1 6.3 17.0 5.5 21.5 14.1 11.3 5.5 12.4 26.2 12.5 11.3 12.2 13.7 25.2 28.7 11.0 8.9 10.5 8.2 7.9 11.0 14.1 14.6 7.0 12.0 13.4 26.9 13.2 16.8 28.5 18.2 8.3 11.4 12.9 26.3 18.5 12.9 9.7 6.5 19.3 18.0 13.0 18.1 6.1 12.8 15.7 15.7 15.1 16.9 8.8 24.5 14.0 18.9 11.5 4.0 14.7 6.5 18.7 13.2 0.7 0.8 0.2 0.8 0.7 0.9 0.4 0.8 0.7 0.7 0.7 0.8 0.8 2.2 0.8 0.8 0.5 0.7 0.6 6.9 11.5 12.4 9.2 5.7 11.4 14.0 10.1 11.3 5.9 10.8 19.2 30.8 22.4 25.1 50.3 40.7 21.9 74.8 5.7 17.6 26.5 34.5 24.5 22.2 8.6 22.6 14.7 43.8 46.5 63.1 14.8 7.9 25.6 21.2 73.1 54.3 37.8 24.2 122.9 32.6 18.2 21.5 44.3 28.5 129.4 17.1 31.6 27.5 14.6 14.9 42.1 36.4 19.1 2.0 26.0 48.5 14.9 37.3 53.0 5.4 32.8 36.0 26.1 32.0 51.3 83.2 37.9 18.6 46.3 46.6 115.0 12.7 9.4 15.4 29.7 32.9 65.9 44.5 3.1 4.0 31.8 23.9 79.1 49.1 12.0 19.3 100.1 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HDLM-2: 64.6;HeLa: 89.5;U-937: 58.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" 42.8 8.9 21.7 27.2 18.8 106.4 28.2 12.2 28.4 22.9 14.7 36.2 5.7 17.8 2.1 7.5 19.1 13.6 24.9 19.9 17.7 21.5 6.5 57.9 28.6 33.6 24.7 15.1 7.6 4.1 10.0 15.1 25.7 16.9 7.8 3.7 18.2 8.5 13.8 15.6 23.7 8.3 22.7 43.9 15.8 6.1 21.2 7.1 20.6 11.7 25.1 12.4 17.6 31.4 16.4 14.8 1.0 3.1 4.4 6.4 2.4 8.5 27.4 3.8 3.0 4.6 15.3 4.2 22.8 17.5 7.5 7.8 4.2 10.0 2.7 64.6 3.6 17.3 89.5 1.4 3.9 17.2 2.4 0.5 5.1 4.2 5.3 9.2 21.1 7.8 0.2 40.7 2.9 5.2 2.6 24.1 1.1 3.2 16.6 2.9 0.8 16.6 14.8 5.6 4.7 3.0 1.8 1.3 1.1 7.3 6.8 27.6 16.7 0.7 6.8 10.6 0.3 8.0 37.0 1.3 2.6 58.6 1.0 24.3 5.4 34.6 0.8 8.0 0.8 5.0 0.6 0.3 4.1 4.3 0.1 0.2 39.8 2.7 10.0 0.1 0.2 3.5 21.7 18.8 12.2 28.4 19.9 17.7 33.6 24.7 25.7 22.7 21.2 31.4 49.0 157.0 35.2 2.6 39.7 15.7 7.6 11.7 7.4 4.5 6.3 2.0 10.1 10.0 18.8 22.0 4.2 0.7 29.5 18.3 1.9 3.5 6.1 15.1 8.1 31.7 4.8 5.7 53.9 3.5 0.6 4.8 16.8 14.5 10.8 1.9 16.4 0.3 24.4 1.7 5.2 7.9 4.1 55.6 22.2 2.8 1.5 39.7 8.8 79.6 33.0 0.7 21.6 1.5 1.1 11.0 9.9 0.7 38.8 20.3 1.5 2.7 15.1 0.5 39.5 2.1 21.5 8.7 8.5 2.9 9.1 0.5 12.5 0.6 4.1 6.3 SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 49.7;Cone photoreceptor cells: 54.2;Endometrial ciliated cells: 57.6;Glandular and luminal cells: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "HMC-1: 18.3;OE19: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" 3.5 2.5 3.8 3.7 4.8 5.8 2.9 1.2 16.6 7.1 14.7 4.4 2.3 4.3 1.5 3.3 7.1 2.7 6.6 5.1 1.5 10.2 0.9 6.7 2.7 6.6 1.0 3.1 7.9 2.5 14.9 5.0 6.6 6.6 1.6 5.4 7.8 5.3 4.6 5.7 4.1 1.7 0.7 4.8 12.5 13.7 2.2 2.3 5.8 1.4 2.0 3.4 2.8 6.1 4.6 9.8 3.7 5.9 0.3 0.3 16.1 2.5 1.5 2.2 1.7 6.4 12.2 0.9 11.8 1.0 3.1 3.7 2.1 1.2 1.0 7.2 3.3 2.7 3.1 0.0 1.7 1.1 18.3 0.8 1.9 1.6 0.9 0.5 1.5 5.0 5.6 0.7 0.8 11.9 11.0 2.5 4.7 30.8 4.1 3.3 0.2 3.1 8.9 7.9 5.5 4.6 2.7 0.8 4.5 2.6 1.9 7.2 0.8 0.0 2.4 3.8 4.9 3.9 12.7 1.3 2.1 4.3 4.0 1.1 0.1 8.3 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 7.0 0.2 0.1 0.3 0.2 0.1 3.8 4.8 1.2 16.6 5.1 1.5 6.6 1.0 6.6 0.7 2.2 6.1 3.3 9.6 12.7 6.5 3.0 2.7 6.6 3.6 5.2 33.1 6.4 5.8 13.5 15.7 8.9 49.7 54.2 8.7 7.5 14.7 0.0 9.3 12.5 57.6 10.8 3.4 2.4 0.0 29.0 2.7 0.8 2.9 37.2 97.1 1.3 1.8 1.1 0.0 6.7 3.3 21.7 7.7 8.2 2.5 3.3 5.9 2.1 8.6 3.6 7.5 1.8 4.3 5.2 6.6 0.9 7.8 4.5 2.2 5.3 6.0 3.7 3.2 22.3 9.2 0.0 1.5 3.2 5.7 2.6 4.4 2.4 16.3 4.6 4.0 5.1 11.3 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 72.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Cell line enriched" "Detected in single" 6 "EFO-21: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 0.8 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.4 2.0 0.0 1.4 0.4 1.9 0.7 0.6 1.5 0.7 1.1 0.0 0.0 0.6 0.2 1.5 0.0 0.0 0.0 1.2 0.2 0.1 0.2 1.2 0.1 0.9 0.3 0.0 0.2 0.8 0.3 0.4 2.1 1.8 0.0 0.2 1.7 0.1 0.0 0.0 0.5 0.4 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.2 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 72.3 0.3 16.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 PTP4A3 "PRL-3, PRL-R, PRL3" ENSG00000184489 "Protein tyrosine phosphatase 4A3" O75365 8 141391995-141432454 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 640.3;pituitary gland: 207.5;skeletal muscle: 738.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 102.9;Cardiomyocytes: 272.8;Cone photoreceptor cells: 123.0;Rod photoreceptor cells: 226.5;Smooth muscle cells: 140.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 55.0;non-classical monocyte: 54.1" "Group enriched" "Detected in all" 6 "granulocytes: 55.0;monocytes: 54.1" "Cell line enhanced" "Detected in many" "HDLM-2: 128.7;Karpas-707: 45.9;RPMI-8226: 38.1;U-266/84: 42.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003281 Uncertain NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "HPA003281: AB_1855903" "unprognostic (1.09e-1)" "unprognostic (3.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.10e-3)" "unprognostic (2.08e-1)" "unprognostic (6.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.27e-2)" "unprognostic (1.08e-1)" "unprognostic (2.50e-1)" "unprognostic (5.73e-3)" "unprognostic (2.33e-2)" "prognostic unfavorable (1.81e-5)" "unprognostic (2.25e-1)" "unprognostic (1.12e-2)" "unprognostic (2.28e-2)" "unprognostic (1.77e-1)" 48.6 16.6 11.4 2.0 9.8 0.7 43.3 9.0 14.1 87.3 9.2 70.7 2.1 69.9 3.0 15.1 67.2 1.4 640.3 10.1 10.6 48.9 9.8 58.4 1.1 10.5 10.3 46.8 116.2 2.6 207.5 2.3 10.7 73.6 0.7 36.0 29.9 2.1 738.1 22.8 37.4 4.4 9.3 56.8 99.7 22.0 13.3 1.1 35.2 62.1 1.3 40.5 35.7 9.2 0.3 0.9 0.6 0.1 0.0 0.2 0.1 0.5 0.1 0.0 0.0 0.1 2.3 0.0 9.8 0.1 0.1 0.0 0.1 0.1 0.0 128.7 1.9 5.2 0.2 1.8 0.5 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.4 1.0 3.1 45.9 0.1 11.3 0.7 0.2 2.1 1.0 0.7 19.3 0.1 38.1 0.0 0.1 11.4 3.9 0.6 0.1 2.6 1.2 1.8 0.0 0.5 0.1 2.2 0.1 0.0 11.6 42.0 0.3 0.1 2.8 0.1 1.5 3.3 12.5 3.1 28.2 1.8 5.1 5.8 3.0 2.0 1.2 6.5 3.4 55.0 1.5 54.1 8.6 5.3 5.1 11.4 9.8 9.0 14.1 10.1 10.6 10.5 10.3 10.7 9.3 13.3 9.2 52.7 3.2 44.5 5.5 21.1 9.9 5.2 23.7 7.4 102.9 9.8 7.4 272.8 4.3 8.3 7.3 123.0 0.3 5.6 0.8 9.8 8.2 10.9 2.0 3.1 57.7 10.2 0.8 5.3 62.9 0.3 21.7 5.6 2.0 1.3 6.6 15.0 0.3 4.1 15.2 10.3 2.9 26.4 2.8 20.1 7.1 3.7 4.0 21.4 8.4 12.8 36.7 2.1 2.5 0.7 10.8 0.2 1.9 79.8 11.9 0.2 5.0 1.1 226.5 32.9 17.1 140.8 4.4 24.8 1.8 10.2 0.3 13.7 3.4 3.0 3.6 AC138647.1 ENSG00000226490 "Novel protein" 8 141514638-141518737 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 12 "brain: 4.0;testis: 9.9" "Group enriched" "Detected in some" 5 "Early spermatids: 226.6;Late spermatids: 66.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 1.2;hypothalamus: 4.0;medulla oblongata: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.2 0.3 4.0 1.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 226.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSNARE1 FLJ31164 ENSG00000171045 "T-SNARE domain containing 1" Q96NA8 8 142212080-142403182 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 26.7;Inhibitory neurons: 23.0;Oligodendrocyte precursor cells: 21.1;Oligodendrocytes: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-937: 24.5" "Low region specificity" "Detected in all" HPA074249 Approved Approved Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "HPA074249: " "unprognostic (2.92e-2)" "unprognostic (1.44e-1)" "unprognostic (3.94e-3)" "unprognostic (1.22e-2)" "unprognostic (1.35e-1)" "unprognostic (1.09e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-3)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.87e-3)" "unprognostic (1.66e-1)" "unprognostic (6.26e-2)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (1.29e-1)" "prognostic favorable (7.33e-4)" 10.1 9.5 10.8 6.6 10.6 4.2 12.0 5.0 19.0 16.3 4.8 11.3 11.6 13.8 2.9 10.4 15.0 5.9 9.1 9.9 7.3 13.6 10.0 9.9 6.7 12.0 8.4 20.4 28.5 7.0 12.9 3.3 9.2 13.7 2.8 4.0 13.4 6.4 11.0 27.3 12.9 3.8 5.9 12.6 13.3 13.4 8.9 6.2 16.3 4.6 4.4 11.8 12.1 14.1 6.6 6.4 4.2 5.3 3.2 2.9 13.2 1.9 3.1 1.9 1.9 2.1 7.0 3.5 10.7 1.5 3.2 5.9 1.9 6.6 0.8 4.0 6.4 4.2 1.7 7.2 8.5 9.5 9.6 5.6 6.2 0.0 4.3 3.9 2.1 18.4 8.4 0.3 1.3 8.7 8.1 8.8 4.2 6.4 15.8 0.0 2.2 6.2 3.6 8.0 17.5 10.6 8.9 7.1 12.8 2.0 4.7 8.2 5.1 3.1 8.5 5.6 4.3 0.5 2.8 5.6 5.7 24.5 3.2 1.6 0.5 0.1 0.9 2.3 0.6 0.3 0.5 0.2 0.6 0.4 0.2 0.3 0.0 0.5 2.0 0.0 0.6 0.6 10.8 10.6 5.0 19.0 9.9 7.3 12.0 8.4 9.2 5.9 8.9 14.1 1.9 0.0 1.1 12.1 2.3 4.5 2.2 0.8 6.8 2.6 1.8 1.8 4.6 2.8 0.5 1.8 2.1 0.3 1.6 1.6 3.9 1.6 2.4 1.9 1.0 1.5 1.8 2.5 26.7 1.8 1.8 1.5 4.1 1.4 0.0 1.2 1.1 1.3 1.9 0.0 23.0 2.1 0.0 2.6 2.9 5.3 0.9 1.7 3.6 12.2 1.5 3.1 2.1 21.1 24.6 1.6 0.2 1.5 1.6 1.3 1.6 1.4 2.3 1.3 0.0 2.3 1.7 5.0 3.7 3.5 7.5 0.3 3.1 0.7 0.9 1.5 ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 37.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Excitatory neurons: 47.5;Horizontal cells: 126.2;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 70.9" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 12.1;MCF7: 4.6;NB-4: 6.1;RPMI-8226: 17.5;U-2 OS: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" 0.6 1.8 21.7 0.3 17.7 0.1 0.6 0.8 37.3 2.9 0.0 0.8 0.3 1.2 0.7 0.7 0.8 0.1 0.5 18.6 13.7 0.7 0.2 0.8 0.4 12.9 9.4 1.3 0.4 1.6 6.4 0.9 13.1 1.5 0.0 1.6 0.9 0.5 0.1 5.0 1.1 0.1 1.2 2.5 0.8 1.9 24.0 0.2 0.6 0.1 0.1 0.4 1.3 5.4 0.0 0.1 0.1 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.9 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 6.1 1.9 0.2 0.0 0.1 0.0 17.5 0.0 0.0 3.2 3.2 0.0 0.0 0.2 0.2 0.1 0.3 0.0 0.1 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 17.7 0.8 37.3 18.6 13.7 12.9 9.4 13.1 1.2 24.0 5.4 0.1 0.0 0.0 58.8 0.3 0.0 0.6 0.0 1.8 18.5 1.3 0.8 5.7 1.5 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.3 0.2 0.0 0.1 0.4 0.0 0.0 47.5 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.0 0.1 126.2 38.0 0.1 0.0 0.3 0.0 1.0 0.3 0.3 0.0 9.4 0.8 3.9 0.0 70.9 2.6 0.1 0.1 13.5 0.0 0.2 0.0 0.2 0.0 0.9 6.6 0.4 0.4 0.0 0.8 0.1 0.0 0.0 0.3 0.3 0.1 0.2 ARC "Arg3.1, KIAA0278" ENSG00000198576 "Activity regulated cytoskeleton associated protein" Q7LC44 8 142611049-142614479 "Predicted intracellular proteins" "Endocytosis, Transport" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 122.9;pituitary gland: 67.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 57.0;Endometrial stromal cells: 47.8;Enteroendocrine cells: 164.2;Skeletal myocytes: 57.7" "Cancer enriched" "Detected in many" 12 "glioma: 36.1" "Group enriched" "Detected in all" 6 "cerebral cortex: 122.9;hippocampal formation: 34.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 8.1;HEK 293: 10.0;SCLC-21H: 23.6;U-2 OS: 11.5;U-87 MG: 12.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basal ganglia: 20.7;cerebral cortex: 75.1;hippocampal formation: 42.4;olfactory bulb: 22.9" "HPA056430, CAB079013" Supported Approved Vesicles,Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Microtubules" "CAB079013: , HPA056430: AB_2683130" "unprognostic (1.40e-3)" "unprognostic (2.95e-2)" "unprognostic (4.35e-3)" "unprognostic (4.87e-4)" "unprognostic (6.83e-2)" "unprognostic (8.12e-2)" "unprognostic (5.13e-2)" "unprognostic (1.77e-1)" "unprognostic (5.07e-2)" "unprognostic (9.43e-2)" "unprognostic (4.15e-3)" "unprognostic (1.40e-1)" "unprognostic (2.14e-2)" "unprognostic (1.01e-2)" "unprognostic (7.42e-2)" "unprognostic (1.54e-1)" "unprognostic (3.35e-2)" 14.2 10.2 6.6 0.4 8.2 0.2 1.2 4.5 122.9 3.3 2.7 1.6 0.2 0.9 0.9 1.6 1.9 2.0 2.1 34.2 14.1 4.0 0.3 8.1 0.0 6.4 4.0 0.6 4.0 0.0 67.6 0.9 4.8 0.8 0.1 0.8 0.8 3.8 0.4 10.9 1.1 0.3 3.6 0.7 8.7 0.6 8.9 0.1 1.0 0.4 0.1 0.7 4.5 13.4 0.0 0.1 0.4 8.1 0.1 0.8 0.0 1.7 0.0 0.4 0.2 0.2 0.0 0.0 1.1 0.3 0.3 0.1 0.5 0.0 0.0 0.0 10.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 3.5 0.0 0.0 3.7 1.4 1.8 0.0 0.8 0.0 0.0 0.0 23.6 5.5 0.6 0.0 0.3 0.0 0.1 0.1 0.0 1.3 11.5 0.9 0.2 2.2 0.1 0.0 12.8 0.0 3.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 8.2 4.5 122.9 34.2 14.1 6.4 4.0 4.8 3.6 8.9 13.4 19.7 0.0 3.0 1.6 1.9 5.1 16.6 2.6 1.2 8.4 33.2 57.0 4.5 4.3 0.8 0.0 0.0 0.1 5.8 6.0 0.0 1.6 0.1 9.2 47.8 9.8 164.2 0.0 17.0 0.0 0.4 24.1 21.9 10.3 0.0 0.5 7.5 0.0 1.6 3.3 0.8 6.2 4.1 0.8 7.0 0.0 0.3 8.2 7.2 1.0 0.1 15.2 0.0 3.5 0.8 0.1 0.0 1.9 1.1 10.3 0.3 0.0 0.3 2.8 0.0 57.7 27.0 0.2 0.6 4.7 6.5 0.1 4.2 0.5 4.1 2.7 JRK "jerky, JH8" ENSG00000234616 "Jrk helix-turn-helix protein" O75564 8 142657460-142681968 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052675 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" No No "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA052675: AB_2681910" "unprognostic (3.65e-2)" "unprognostic (5.30e-2)" "unprognostic (9.67e-2)" "unprognostic (3.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.84e-2)" "unprognostic (6.58e-6)" "unprognostic (1.05e-1)" "unprognostic (3.87e-1)" "unprognostic (6.90e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (7.50e-2)" "unprognostic (2.07e-1)" "unprognostic (2.53e-1)" "unprognostic (1.22e-2)" "unprognostic (1.69e-2)" 3.7 4.5 5.9 4.1 6.1 2.1 4.0 7.9 7.4 7.4 4.0 5.9 3.0 6.7 3.4 4.9 5.5 2.5 5.9 5.8 4.7 7.9 4.0 3.9 5.4 6.2 5.2 8.5 5.4 4.6 6.4 3.0 5.5 6.2 2.8 3.8 4.7 4.0 7.5 6.0 5.3 3.7 4.3 7.2 5.7 6.6 6.2 5.1 6.9 4.7 5.9 5.7 4.7 6.8 6.5 6.9 8.0 6.4 7.6 10.8 4.8 10.4 4.2 11.9 6.8 6.3 13.1 11.0 4.1 8.2 8.2 8.7 7.0 6.2 6.0 8.5 12.0 11.2 25.3 7.2 3.1 8.6 7.5 7.2 5.4 7.6 4.3 6.0 6.8 13.1 12.0 4.8 10.1 11.1 10.1 4.8 6.8 4.6 9.6 13.1 5.0 6.2 4.1 11.1 14.5 9.6 18.1 7.3 4.3 5.0 7.3 5.2 8.1 9.1 19.5 9.1 5.5 6.3 7.6 6.3 6.9 10.7 9.0 1.0 0.7 0.9 0.9 0.5 0.5 0.4 1.0 0.9 0.7 1.2 1.3 1.0 0.8 0.6 0.2 0.6 0.6 0.4 5.9 6.1 7.9 7.4 5.8 4.7 6.2 5.2 5.5 4.3 6.2 6.8 3.5 6.4 1.1 8.5 4.8 0.0 2.5 0.0 2.2 14.7 4.5 3.3 11.5 4.3 0.6 7.3 20.9 4.4 8.6 3.2 3.9 2.8 1.9 1.4 4.9 6.5 9.1 12.0 11.3 2.5 2.7 3.7 6.6 2.1 1.3 15.5 8.2 2.6 3.0 10.1 11.0 3.1 0.0 6.6 0.0 2.2 11.5 3.4 0.0 8.4 4.5 4.4 12.3 9.5 9.5 5.6 1.4 11.7 4.3 3.7 2.7 2.7 0.7 10.0 0.0 5.8 4.8 9.1 19.4 3.2 0.0 2.2 2.5 6.8 4.2 4.5 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 THEM6 "C8orf55, DSCD75" ENSG00000130193 "Thioesterase superfamily member 6" Q8WUY1 8 142727223-142736927 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 82.4;RT4: 114.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA023255 Uncertain Approved "Nuclear speckles,Cytosol" "Secreted - unknown location" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "HPA023255: AB_1845782" "unprognostic (6.20e-3)" "unprognostic (2.21e-1)" "unprognostic (9.10e-2)" "unprognostic (5.33e-2)" "unprognostic (3.44e-2)" "unprognostic (1.00e-2)" "unprognostic (1.74e-2)" "unprognostic (6.47e-2)" "unprognostic (2.76e-1)" "unprognostic (1.44e-1)" "unprognostic (4.91e-2)" "unprognostic (6.76e-2)" "prognostic favorable (6.66e-7)" "unprognostic (7.02e-3)" "unprognostic (3.55e-2)" "unprognostic (2.39e-2)" "prognostic favorable (4.49e-4)" 14.3 17.2 15.8 4.4 13.9 5.3 15.6 14.4 18.3 9.6 12.0 13.3 11.5 6.9 3.5 21.0 9.4 7.3 16.6 16.1 15.4 21.6 47.0 10.6 6.5 20.7 17.2 4.4 23.1 15.7 12.5 8.3 16.7 12.5 5.1 1.4 16.3 10.3 12.4 16.6 11.6 3.5 15.0 11.0 15.6 3.7 15.9 6.8 14.2 7.2 4.1 17.2 11.5 14.2 28.5 23.1 3.5 23.9 10.9 3.8 16.6 14.3 11.8 21.5 14.9 14.2 41.5 11.9 31.8 5.4 8.0 64.4 10.2 31.0 3.5 9.9 28.2 9.1 12.3 28.9 11.9 5.3 9.2 5.5 10.9 4.2 6.0 4.3 18.4 16.6 4.3 5.9 3.7 82.4 21.7 1.3 5.4 53.0 74.5 24.9 2.4 27.4 25.9 114.0 53.1 20.8 21.9 64.7 18.6 3.2 31.9 4.3 10.7 9.2 6.7 26.8 2.5 3.8 5.6 5.2 9.5 25.7 11.6 7.2 4.9 2.6 10.9 9.2 16.6 5.1 11.6 14.1 4.7 6.7 13.6 12.9 0.7 11.1 9.0 3.6 11.6 9.1 15.8 13.9 14.4 18.3 16.1 15.4 20.7 17.2 16.7 15.0 15.9 14.2 35.4 9.6 5.8 6.2 6.7 3.6 7.5 5.7 2.8 10.4 24.7 25.3 7.4 11.5 7.8 18.4 6.2 18.3 11.5 16.6 5.9 13.7 3.3 5.5 3.0 14.6 31.8 11.6 11.3 11.6 10.1 4.8 7.7 9.0 0.0 6.6 19.2 20.8 11.4 16.8 7.8 13.5 6.1 3.1 1.4 15.7 2.8 3.9 5.4 2.8 2.3 13.5 16.5 11.6 7.3 9.4 9.0 4.1 3.7 10.7 29.0 16.2 2.4 11.3 0.0 6.1 4.3 2.7 5.7 18.4 7.7 3.4 10.3 8.2 22.4 25.1 SLURP1 "ANUP, ARS, ArsB, LY6-MT, LY6LS, MDM" ENSG00000126233 "Secreted LY6/PLAUR domain containing 1" P55000 8 142740949-142742406 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Cytokine "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 1039.2;skin 1: 858.5" "Group enriched" "Detected in some" 16 "Squamous epithelial cells: 20.8;Suprabasal keratinocytes: 65.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 66.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;MCF7: 1.5;RT4: 1.1;T-47d: 2.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA050967 Approved "Secreted in other tissues" NA NA 7700000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA050967: AB_2681293" "unprognostic (1.22e-2)" "unprognostic (5.08e-2)" "unprognostic (1.16e-2)" "unprognostic (1.42e-2)" "unprognostic (1.84e-1)" "unprognostic (7.32e-2)" "unprognostic (5.99e-2)" "unprognostic (1.33e-4)" "unprognostic (1.58e-1)" "unprognostic (2.98e-1)" "unprognostic (1.43e-1)" 0.9 0.6 0.1 0.0 0.0 0.0 11.3 0.7 0.5 105.0 0.0 0.3 0.0 0.2 0.0 1039.2 0.2 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.2 0.6 0.0 0.5 0.0 0.0 0.3 0.0 0.0 70.1 0.0 1.4 858.5 0.3 0.0 0.0 0.2 0.8 0.3 0.1 0.9 0.2 0.0 17.4 0.3 206.7 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.2 0.6 0.0 0.0 1.8 1.5 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 20.8 65.8 0.0 0.0 0.0 0.0 0.8 LYPD2 "LYPDC2, RGTR430, UNQ430" ENSG00000197353 "LY6/PLAUR domain containing 2" Q6UXB3 8 142750150-142752532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "esophagus: 347.8" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 97.0;Club cells: 378.7;Ionocytes: 71.2;Respiratory ciliated cells: 77.4" "Cancer enhanced" "Detected in many" "cervical cancer: 45.9;ovarian cancer: 46.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 13 "non-classical monocyte: 440.1" "Lineage enriched" "Detected in many" 22 "monocytes: 440.1" "Cell line enhanced" "Detected in some" "EFO-21: 10.2;HaCaT: 2.8;OE19: 1.9" "Low region specificity" "Detected in many" HPA028599 Uncertain "Intracellular and membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "HPA028599: AB_10603777" "prognostic favorable (2.00e-4)" "unprognostic (3.10e-2)" "prognostic favorable (2.63e-4)" "unprognostic (3.85e-3)" "unprognostic (3.75e-2)" "unprognostic (2.49e-1)" "unprognostic (1.57e-2)" "unprognostic (3.11e-3)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.12e-1)" "unprognostic (2.04e-1)" 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.4 15.0 0.0 0.0 0.0 0.0 0.0 347.8 0.3 0.2 2.9 0.0 0.0 0.1 1.3 1.5 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.0 0.1 0.0 0.0 27.0 0.0 0.1 28.8 0.1 0.0 0.0 0.2 23.2 0.0 0.1 2.5 0.0 0.0 26.3 0.0 48.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 33.7 0.4 2.0 0.1 0.2 20.1 0.0 0.2 0.1 0.0 0.0 440.1 1.6 0.1 10.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 97.0 0.0 0.0 0.1 0.0 0.0 0.0 378.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 5.7 0.4 0.4 0.0 0.0 0.0 71.2 1.3 0.0 0.1 0.0 25.3 0.0 0.0 11.2 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 77.4 0.0 0.0 0.0 22.3 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.0 0.2 LYNX1-SLURP2 ENSG00000284505 "LYNX1-SLURP2 readthrough" 8 142764334-142778224 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 6.3;intestine: 7.0" "Cell type enriched" "Detected in single" 12 "Pancreatic endocrine cells: 10.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 8 "monocytes: 1.4" "Cell line enhanced" "Detected in single" "BJ: 1.0" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" 1.5 1.0 0.3 0.2 0.4 0.0 0.5 1.1 2.5 2.1 0.3 7.0 0.3 2.0 0.3 6.3 1.3 0.3 1.5 0.7 0.2 0.5 0.9 0.4 0.1 1.4 0.3 0.6 0.2 0.5 1.0 0.1 1.4 1.8 0.2 0.2 0.7 1.7 0.8 3.4 1.0 0.3 0.6 0.3 2.2 0.6 0.6 0.0 0.4 0.2 0.3 3.8 2.5 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.4 1.1 2.5 0.7 0.2 1.4 0.3 1.4 0.6 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLURP2 ENSG00000283992 "Secreted LY6/PLAUR domain containing 2" P0DP57 8 142764338-142769828 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 870.8;skin 1: 334.1;vagina: 219.7" "Cell type enhanced" "Detected in single" "Pancreatic endocrine cells: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 28.5" "Secreted in other tissues" NA NA 3100000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" 1.1 0.1 0.4 0.0 0.7 0.0 2.0 2.9 2.4 187.1 0.0 19.4 0.3 5.0 0.2 870.8 4.0 0.2 1.2 1.0 0.1 0.2 0.3 0.5 0.0 1.8 0.2 1.0 0.4 0.0 0.2 0.1 1.7 6.5 0.2 0.3 75.2 2.1 0.4 334.1 2.8 0.8 0.2 0.3 5.8 0.3 0.4 1.2 0.6 0.0 22.9 9.9 219.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.1 6.2 0.0 0.0 28.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 2.9 2.4 1.0 0.1 1.8 0.2 1.7 0.2 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LYNX1 SLURP2 ENSG00000180155 "Ly6/neurotoxin 1" P0DP58 8 142771197-142777810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 136.8;heart muscle: 79.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 34.8;Cardiomyocytes: 76.0;Club cells: 110.5;Excitatory neurons: 35.3;Hepatocytes: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12 "intermediate monocyte: 6.6;non-classical monocyte: 17.5" "Lineage enriched" "Detected in many" 17 "monocytes: 17.5" "Cell line enhanced" "Detected in many" "BJ: 7.9;fHDF/TERT166: 8.9;GAMG: 11.4;HHSteC: 8.3;HSkMC: 7.5;OE19: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 310000 "Cluster 51: Monocytes - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "unprognostic (8.67e-2)" "unprognostic (6.96e-2)" "unprognostic (1.31e-2)" "unprognostic (2.79e-3)" "unprognostic (1.04e-3)" "unprognostic (5.13e-3)" "unprognostic (1.33e-1)" "unprognostic (5.55e-3)" "unprognostic (1.12e-1)" "unprognostic (3.61e-3)" "unprognostic (7.21e-2)" "unprognostic (1.03e-2)" "prognostic favorable (2.82e-4)" "unprognostic (2.02e-2)" "unprognostic (2.28e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-1)" 11.2 28.5 11.4 3.5 22.1 0.3 10.4 3.0 136.8 13.2 0.0 18.6 4.0 19.7 4.9 20.8 18.8 9.1 79.0 79.6 7.1 14.4 35.0 9.2 1.8 47.0 14.8 12.8 10.1 28.4 15.0 2.9 41.2 17.5 2.5 7.0 17.3 13.4 6.2 23.9 6.4 11.2 0.0 13.1 11.4 3.1 33.3 0.8 9.4 11.5 2.1 15.0 13.5 56.7 0.1 5.6 0.3 0.0 2.2 0.3 0.1 7.9 0.6 1.1 1.3 0.3 1.3 0.0 3.9 8.9 11.4 1.5 0.2 0.0 0.3 0.0 0.2 0.0 0.2 1.4 8.3 0.0 3.8 7.5 1.3 2.3 0.0 0.2 0.9 0.0 0.0 0.3 0.8 0.0 0.0 0.1 1.9 7.8 0.1 0.0 0.0 0.0 3.0 0.0 0.6 4.5 0.6 6.1 0.0 3.5 6.5 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 6.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.1 0.0 0.0 17.5 0.0 0.0 0.3 11.4 22.1 3.0 136.8 79.6 7.1 47.0 14.8 41.2 0.0 33.3 56.7 2.5 0.0 0.0 8.8 0.3 5.7 1.1 34.8 0.6 8.7 7.8 3.8 76.0 4.3 110.5 0.0 0.0 0.2 0.1 0.0 3.9 1.0 0.3 0.1 1.5 5.8 0.0 2.7 35.3 0.4 0.3 6.1 1.1 0.1 1.3 1.1 15.4 34.5 3.5 21.9 22.0 0.2 16.2 3.2 3.6 1.2 5.0 1.7 5.4 8.4 0.4 12.3 0.0 7.1 12.9 0.3 0.0 8.2 0.1 1.0 0.0 2.7 26.6 6.3 6.6 6.9 18.9 0.7 1.9 30.7 33.2 0.5 0.3 2.4 0.0 3.1 LY6D E48 ENSG00000167656 "Lymphocyte antigen 6 family member D" Q14210 8 142784882-142786539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2074.3;skin 1: 850.4;vagina: 491.2" "Group enriched" "Detected in many" 9 "Basal keratinocytes: 1171.6;Squamous epithelial cells: 1913.0;Suprabasal keratinocytes: 3866.1" "Group enriched" "Detected in many" 7 "cervical cancer: 409.8;head and neck cancer: 444.6;urothelial cancer: 242.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "A-431: 162.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA024755, HPA064317" Enhanced NA NA 210000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "HPA024755: AB_1853410, HPA064317: AB_2685244" "unprognostic (2.13e-2)" "unprognostic (7.48e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-2)" "unprognostic (8.97e-2)" "unprognostic (1.51e-2)" "unprognostic (3.84e-1)" "unprognostic (5.11e-2)" "prognostic unfavorable (1.94e-6)" "unprognostic (8.68e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.50e-1)" "unprognostic (3.97e-1)" "unprognostic (5.40e-4)" "unprognostic (1.06e-1)" 1.7 47.6 0.6 0.2 0.6 0.0 20.4 0.5 1.4 297.4 0.5 0.9 0.0 0.3 0.0 2074.3 1.0 1.4 0.8 0.6 0.5 0.3 0.8 0.5 0.0 0.5 0.5 0.5 1.0 0.0 1.0 2.5 0.5 15.3 0.2 0.0 235.4 0.3 2.6 850.4 0.5 0.0 0.5 0.5 12.4 0.4 0.5 4.6 0.4 0.0 75.6 65.2 491.2 0.7 162.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.0 0.0 1.3 0.0 0.2 0.0 0.0 4.0 11.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 1.2 4.0 0.2 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.4 0.6 0.5 0.5 0.5 0.5 0.5 0.5 0.7 0.1 3.2 0.0 0.0 0.0 1171.6 9.4 244.9 138.3 0.0 14.8 14.1 0.2 0.0 154.0 1.8 0.0 0.9 0.1 0.4 1.9 1.1 0.0 0.4 0.1 10.7 0.0 0.0 0.3 0.2 5.7 9.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 22.4 0.0 137.3 0.0 0.0 0.8 163.7 0.0 0.0 0.0 0.0 0.0 0.1 7.0 0.0 0.0 2.5 18.9 0.0 1.2 12.2 0.0 0.0 0.6 16.1 0.0 0.0 1913.0 3866.1 8.2 4.0 0.0 0.4 164.6 GML LY6DL ENSG00000104499 "Glycosylphosphatidylinositol anchored molecule like" Q99445 8 142834247-142916506 "Predicted intracellular proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 56 "adrenal gland: 194.0" "Cell type enhanced" "Detected in some" "granulocytes: 4.5;Sertoli cells: 6.6;Spermatocytes: 24.2;Spermatogonia: 7.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 2.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" 0.0 194.0 0.0 0.2 2.7 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 24.2 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 CYP11B1 "CPN1, CYP11B, FHI, P450C11" ENSG00000160882 "Cytochrome P450 family 11 subfamily B member 1" P15538 8 142872356-142879846 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 877 "adrenal gland: 3686.5" "Group enriched" "Detected in some" 113 "Early spermatids: 53.3;Late spermatids: 83.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Approved Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.2 3686.5 0.1 0.9 0.6 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.4 0.3 0.0 0.9 0.5 0.3 0.0 0.1 0.1 0.3 0.5 0.0 0.4 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.4 4.2 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP11B2 "ALDOS, CPN2, CYP11B, CYP11BL, P-450C18, P450aldo" ENSG00000179142 "Cytochrome P450 family 11 subfamily B member 2" P19099 8 142910559-142917843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 603 "adrenal gland: 179.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049171, HPA049565, HPA056348, HPA057752" Supported Uncertain Mitochondria NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 43: Cardiomyocytes - Nuclear processes" Mitochondria "HPA049171: AB_2680661, HPA049565: , HPA056348: AB_2683104, HPA057752: AB_2683516" 0.0 179.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LY6E "RIG-E, SCA-2, TSA-1" ENSG00000160932 "Lymphocyte antigen 6 family member E" Q16553 8 143017982-143023832 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 614.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1386.5;Extravillous trophoblasts: 4724.2;Granulosa cells: 998.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 753.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 627.1;BJ hTERT+ SV40 Large T+ RasG12V: 888.7;MCF7: 878.7" "Intracellular and membrane" NA NA 44000 "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "unprognostic (3.88e-2)" "unprognostic (3.70e-3)" "unprognostic (9.08e-3)" "unprognostic (2.11e-1)" "unprognostic (2.28e-1)" "unprognostic (6.64e-2)" "unprognostic (4.94e-1)" "unprognostic (7.34e-2)" "unprognostic (1.74e-3)" "unprognostic (1.71e-2)" "prognostic unfavorable (6.74e-8)" "unprognostic (2.68e-1)" "unprognostic (2.28e-3)" "unprognostic (1.84e-3)" "unprognostic (2.12e-2)" 221.7 248.1 95.6 47.9 99.3 120.5 205.6 94.4 133.8 218.1 89.1 80.1 24.8 143.5 36.9 187.1 157.0 85.9 141.1 117.3 92.8 214.6 614.0 232.2 40.6 101.0 89.9 199.3 58.4 23.1 92.5 88.8 92.1 143.1 15.3 4.8 140.4 47.3 38.4 130.2 79.0 50.2 103.5 218.3 72.7 52.4 96.3 56.5 94.7 37.6 30.3 107.6 159.2 91.8 75.8 114.5 2.4 98.9 147.9 267.8 161.4 174.7 504.5 627.1 888.7 1.8 204.3 19.2 122.0 214.8 75.1 216.2 60.2 102.7 72.5 13.4 17.9 76.0 54.1 75.5 106.3 7.0 45.0 230.3 37.4 96.1 42.3 68.5 37.9 32.2 17.9 248.8 45.1 878.7 49.0 56.9 41.0 439.2 34.5 32.2 0.8 98.4 153.8 82.3 94.8 12.8 142.3 216.1 231.9 96.3 236.8 44.7 7.2 26.9 66.4 73.9 0.9 1.0 4.7 1.9 56.6 27.4 96.7 14.0 124.4 15.4 186.5 565.5 71.2 129.5 137.1 123.6 72.8 160.1 75.8 125.7 34.8 272.7 753.3 7.6 121.3 241.1 95.6 99.3 94.4 133.8 117.3 92.8 101.0 89.9 92.1 103.5 96.3 91.8 318.1 22.4 13.4 3.3 141.6 175.5 427.7 528.1 255.6 8.7 301.7 492.0 4.5 255.9 440.5 46.0 0.0 1386.5 149.6 2.4 23.5 298.8 3.8 13.5 233.3 312.0 29.3 76.6 21.4 22.7 4724.2 295.8 43.3 18.9 53.3 998.5 151.0 314.0 365.9 47.1 13.1 20.1 130.2 104.3 225.3 10.0 289.8 176.4 158.3 26.2 111.5 18.7 436.7 5.5 3.6 196.8 0.6 222.3 121.6 240.5 2.0 212.3 112.8 3.6 144.7 34.9 151.6 1.5 45.1 238.6 117.3 534.3 229.6 99.8 14.4 593.7 LY6L ENSG00000261667 "Lymphocyte antigen 6 family member L" H3BQJ8 8 143080457-143083001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.1;kidney: 1.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 2.8" "Region enhanced" "Detected in single" "thalamus: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 7: Kidney - Transmembrane transport" "unprognostic (5.25e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LY6H NMLY6 ENSG00000176956 "Lymphocyte antigen 6 family member H" O94772 8 143157914-143160711 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.7;choroid plexus: 35.0;pituitary gland: 55.5" "Cell type enhanced" "Detected in some" "Adipocytes: 20.0;Endothelial cells: 18.7;Enteroendocrine cells: 54.9;Excitatory neurons: 24.8;Inhibitory neurons: 47.8;Ionocytes: 22.4;Oligodendrocyte precursor cells: 22.6;Spermatogonia: 22.4" "Cancer enhanced" "Detected in many" "glioma: 9.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "MOLT-4: 2.9;SCLC-21H: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077218 Enhanced "Intracellular and membrane" NA NA 12000 "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "HPA077218: " "unprognostic (8.76e-2)" "unprognostic (2.76e-1)" "unprognostic (1.41e-2)" "unprognostic (9.45e-4)" "unprognostic (3.34e-3)" "unprognostic (1.82e-1)" "unprognostic (1.71e-4)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-3)" "unprognostic (3.76e-3)" "unprognostic (5.97e-2)" "unprognostic (2.20e-5)" "unprognostic (6.43e-3)" "unprognostic (1.54e-1)" "unprognostic (8.98e-2)" "unprognostic (9.89e-3)" 2.2 0.4 78.5 0.2 90.6 0.0 0.8 35.7 114.7 1.5 35.0 24.0 2.5 1.6 0.0 1.3 2.0 0.0 0.3 97.9 111.5 0.6 0.1 1.4 0.1 43.4 56.3 1.0 1.0 0.0 55.5 0.0 48.7 0.9 0.0 0.5 0.1 0.0 0.2 0.4 6.6 0.4 46.2 0.2 11.8 5.8 92.6 0.0 0.9 0.0 0.0 0.6 0.4 54.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.5 90.6 35.7 114.7 97.9 111.5 43.4 56.3 48.7 46.2 92.6 54.3 20.0 0.0 0.0 9.1 0.0 0.6 0.2 0.3 0.0 5.8 0.6 0.0 6.2 0.0 0.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.8 0.1 18.7 54.9 0.0 24.8 0.0 0.1 3.7 12.2 0.0 0.0 2.7 0.0 0.0 0.1 0.0 47.8 0.9 22.4 0.0 0.0 2.2 0.0 0.1 0.0 13.1 0.0 2.3 0.0 22.6 5.9 0.1 0.0 0.0 0.0 1.4 0.0 0.0 2.2 3.5 0.0 0.1 0.4 1.9 22.4 0.3 0.0 0.0 0.0 2.5 0.2 0.5 GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;breast: 54.5" "Cell type enriched" "Detected in some" 4 "Adipocytes: 356.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "Karpas-707: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066302 Enhanced "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "HPA066302: AB_2685654" "unprognostic (2.05e-1)" "unprognostic (3.11e-2)" "unprognostic (1.71e-3)" "unprognostic (2.43e-3)" "unprognostic (1.58e-1)" "unprognostic (9.50e-2)" "unprognostic (1.75e-3)" "unprognostic (8.01e-2)" "unprognostic (2.04e-1)" "unprognostic (1.30e-1)" "unprognostic (9.31e-2)" "unprognostic (8.69e-2)" "unprognostic (5.06e-3)" "unprognostic (9.65e-3)" "unprognostic (1.41e-1)" "unprognostic (5.96e-2)" "unprognostic (2.85e-3)" 90.7 4.9 12.9 0.4 23.7 0.1 54.5 22.7 27.2 8.7 7.5 5.3 0.6 11.4 0.2 3.5 11.7 6.5 38.6 13.3 17.9 11.0 1.6 27.4 2.4 35.8 20.8 6.6 1.8 1.1 3.4 6.5 32.9 3.9 0.5 0.1 4.1 1.6 30.2 7.4 3.7 2.4 18.0 19.3 4.1 2.0 22.8 1.9 5.5 29.7 1.0 10.5 7.9 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 23.7 22.7 27.2 13.3 17.9 35.8 20.8 32.9 18.0 22.8 53.5 356.5 0.0 3.2 0.0 0.5 1.5 0.1 0.0 1.2 0.0 1.0 0.6 4.3 0.0 0.6 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 77.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 1.3 0.0 35.7 0.4 0.0 0.0 0.1 0.0 0.0 0.8 2.1 0.6 1.5 0.4 0.0 8.4 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 5.4 3.0 0.0 0.7 0.2 1.1 0.0 0.4 1.1 0.0 0.2 ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (4.92e-2)" "unprognostic (7.18e-2)" "unprognostic (3.53e-2)" "unprognostic (4.16e-3)" "unprognostic (2.98e-1)" "unprognostic (1.55e-2)" "unprognostic (6.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" 2.9 3.5 5.4 2.3 6.6 1.5 2.8 2.8 6.9 3.6 0.0 3.8 3.4 4.2 1.4 2.9 4.1 1.9 3.1 4.9 6.6 3.9 3.4 2.2 2.6 7.8 5.6 5.3 3.5 4.0 5.3 1.1 5.7 3.7 1.5 2.4 4.8 2.6 3.2 4.9 3.6 2.0 2.4 3.2 3.6 6.3 8.2 2.4 4.1 1.8 2.1 3.4 3.0 9.7 6.7 10.5 4.5 6.0 5.1 3.9 5.3 4.0 2.1 7.6 5.2 5.2 5.5 3.7 5.8 5.2 7.7 5.4 4.9 5.2 3.7 5.9 6.0 4.7 5.6 4.1 7.1 1.8 2.8 4.1 7.2 4.9 7.2 5.2 3.6 2.6 10.1 3.5 3.6 12.0 5.0 2.0 6.7 8.2 10.3 2.6 3.7 1.3 3.3 6.0 5.7 7.8 11.2 3.0 5.9 3.8 7.7 3.6 3.8 5.7 10.2 4.5 6.4 5.6 4.6 1.7 5.1 4.5 7.7 0.0 0.1 0.0 0.3 0.2 0.5 0.1 0.2 0.2 0.1 0.2 0.4 0.3 0.0 0.1 0.0 0.9 0.2 0.2 5.4 6.6 2.8 6.9 4.9 6.6 7.8 5.6 5.7 2.4 8.2 9.7 1.6 0.0 2.0 2.9 2.3 1.1 0.7 0.8 0.6 2.5 2.3 1.9 3.2 5.7 1.1 3.7 6.2 0.3 0.8 3.7 1.9 1.9 1.5 1.8 2.3 1.6 3.0 0.8 2.2 0.9 1.1 1.6 2.6 1.2 0.0 2.7 2.5 3.9 1.2 6.7 3.4 2.4 2.0 2.2 0.5 2.6 1.2 1.5 1.8 1.0 0.9 2.5 2.1 1.5 4.4 1.6 4.1 2.2 1.6 0.5 3.4 1.4 3.2 2.0 0.0 1.6 1.9 7.9 3.7 1.8 0.3 0.3 0.9 1.6 3.4 0.4 AC138696.1 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.7;MOLT-4: 1.2" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.87e-1)" "unprognostic (8.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.20e-1)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-2)" "unprognostic (3.99e-1)" "unprognostic (2.59e-2)" "unprognostic (4.06e-1)" 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.4 0.4 0.6 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.2 0.4 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.3 1.7 0.1 0.1 0.5 1.1 0.6 0.2 0.0 0.7 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 1.0 0.4 0.0 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.3 0.6 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.2 1.1 0.0 0.8 0.2 0.5 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.3 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 40: NK-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Cytokinetic bridge" "HPA023131: AB_2671080" "unprognostic (4.98e-2)" "unprognostic (2.69e-1)" "unprognostic (5.64e-3)" "unprognostic (1.65e-1)" "unprognostic (9.07e-2)" "unprognostic (2.71e-2)" "unprognostic (1.00e-2)" "unprognostic (4.57e-2)" "unprognostic (2.22e-1)" "unprognostic (2.65e-1)" "unprognostic (7.45e-3)" "unprognostic (5.03e-1)" "unprognostic (6.88e-3)" "unprognostic (4.61e-2)" "unprognostic (1.23e-1)" "unprognostic (3.21e-2)" "unprognostic (3.71e-3)" 11.6 6.6 8.8 4.7 8.2 5.8 10.7 8.3 15.4 12.3 3.3 10.8 6.4 10.3 2.1 12.8 10.2 2.7 13.0 9.6 7.1 13.7 12.0 6.9 5.6 7.4 6.8 13.4 12.6 4.6 9.3 2.0 7.5 13.4 3.7 2.5 9.2 3.9 9.2 12.9 10.4 1.8 5.1 11.6 11.5 10.4 7.5 5.5 10.1 2.0 4.8 11.3 11.1 7.2 6.7 13.5 6.2 9.9 9.9 4.1 7.0 3.9 2.3 2.9 3.5 3.9 19.1 8.7 7.2 6.5 4.2 8.7 3.4 4.3 1.9 15.3 10.3 13.4 7.1 4.6 7.1 4.2 4.3 12.9 2.3 4.0 8.5 6.7 6.4 13.2 7.2 14.1 8.0 18.5 19.7 3.5 5.8 12.8 19.0 11.9 2.9 8.8 7.0 15.0 6.0 7.0 11.7 5.0 8.2 5.7 22.1 1.9 3.6 4.3 12.1 6.2 4.1 18.6 9.7 7.0 7.0 8.0 7.3 0.0 0.3 0.0 0.3 0.3 0.6 0.4 0.4 0.2 0.1 0.3 0.6 0.2 0.3 1.1 0.0 1.1 0.6 0.2 8.8 8.2 8.3 15.4 9.6 7.1 7.4 6.8 7.5 5.1 7.5 7.2 9.5 0.0 0.0 13.1 11.2 7.4 12.7 1.3 13.6 14.6 10.9 12.2 2.0 12.8 1.1 12.9 20.9 5.0 20.6 15.4 25.4 2.6 6.3 8.2 10.6 6.8 11.5 5.9 7.2 4.0 4.5 9.5 11.7 7.3 4.5 15.8 8.9 7.7 7.2 6.7 8.4 7.6 2.0 10.1 5.7 4.3 16.1 9.9 8.8 12.2 6.9 11.9 13.4 4.5 15.5 3.6 17.9 16.6 8.8 9.4 16.4 20.1 2.3 11.9 6.6 11.2 10.6 13.4 14.7 15.8 10.7 2.9 11.9 14.6 13.7 9.9 ZNF696 FLJ14129 ENSG00000185730 "Zinc finger protein 696" Q9H7X3 8 143289676-143299952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057855, HPA072473" Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 48: NK-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 9: U-2 OS - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm Nucleoli "HPA057855: AB_2683545, HPA072473: AB_2686524" "unprognostic (3.23e-2)" "prognostic unfavorable (6.63e-5)" "unprognostic (3.62e-2)" "prognostic unfavorable (3.52e-5)" "unprognostic (2.58e-1)" "unprognostic (7.86e-2)" "unprognostic (2.76e-3)" "unprognostic (8.82e-2)" "unprognostic (3.16e-1)" "unprognostic (3.02e-1)" "prognostic favorable (1.41e-4)" "unprognostic (6.57e-2)" "unprognostic (8.22e-2)" "unprognostic (7.99e-2)" "unprognostic (2.86e-1)" "unprognostic (3.42e-3)" "unprognostic (8.09e-3)" 4.0 3.3 3.9 3.3 3.7 3.5 3.2 5.9 6.1 3.4 0.0 3.3 6.0 4.5 2.5 2.6 3.4 2.1 2.8 4.2 2.5 3.3 4.6 2.8 3.8 5.6 3.0 4.7 5.0 4.3 3.2 2.7 5.0 3.1 1.9 3.6 5.7 2.3 3.9 6.6 3.7 2.3 0.9 4.0 3.3 3.5 3.4 2.1 3.7 2.4 3.0 3.7 2.8 4.9 8.2 7.4 7.8 8.8 3.2 2.5 14.9 6.3 2.4 4.4 2.7 4.3 6.3 0.7 8.2 2.5 2.5 5.8 8.5 3.8 4.5 9.1 17.9 10.8 8.8 6.7 3.4 4.5 13.5 2.4 6.1 3.0 6.8 3.3 2.2 6.4 22.2 5.3 3.1 17.3 4.6 8.8 10.2 9.7 17.1 9.8 4.4 8.1 3.0 6.3 11.6 16.1 9.3 6.7 8.2 5.3 10.3 8.1 4.5 6.2 13.4 5.5 10.9 9.7 7.3 10.0 4.2 9.2 7.5 1.2 2.0 1.7 2.9 1.1 3.0 2.4 2.1 3.1 2.1 3.2 3.9 3.5 1.2 3.5 2.0 3.8 0.7 1.9 3.9 3.7 5.9 6.1 4.2 2.5 5.6 3.0 5.0 0.9 3.4 4.9 2.2 0.0 0.0 3.6 3.0 2.9 2.3 0.6 0.0 5.3 1.5 1.3 2.8 2.8 0.3 3.7 6.2 1.7 1.8 2.1 3.9 2.4 1.2 0.8 2.3 2.5 0.0 1.3 3.4 2.0 1.8 1.9 2.0 1.0 0.0 2.9 2.2 2.2 1.2 3.3 3.9 1.0 2.0 0.9 0.7 2.4 4.1 0.7 1.8 1.0 0.9 1.8 6.2 4.5 3.1 1.5 0.3 1.2 2.3 1.7 2.7 1.9 0.3 4.5 6.6 1.7 2.2 3.0 5.7 1.1 2.0 0.4 2.5 2.7 2.0 0.6 TOP1MT ENSG00000184428 "DNA topoisomerase I mitochondrial" Q969P6 8 143304384-143359979 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "DNA-binding, Isomerase, Topoisomerase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MOLT-4: 197.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001915, HPA021542" Approved Supported Mitochondria NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 32: Non-specific - Translation" Mitochondria "HPA001915: AB_1080331, HPA021542: AB_1858186" "unprognostic (5.02e-3)" "unprognostic (3.79e-2)" "unprognostic (6.57e-2)" "unprognostic (6.92e-3)" "unprognostic (2.32e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-3)" "unprognostic (1.44e-1)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (1.52e-7)" "unprognostic (3.66e-2)" "unprognostic (3.62e-2)" "unprognostic (8.55e-3)" "unprognostic (5.66e-3)" 14.0 17.4 7.3 9.4 6.1 48.2 13.7 2.5 7.8 23.2 4.0 12.6 7.6 11.7 4.8 18.4 13.4 9.2 7.6 8.5 5.8 14.4 30.3 10.5 12.0 7.0 4.7 32.1 18.9 10.1 9.2 7.4 7.1 13.2 9.7 2.0 14.2 8.1 7.3 22.6 11.6 7.8 2.9 12.6 12.9 23.4 5.4 21.4 21.9 3.4 11.4 17.8 19.1 6.4 25.5 38.3 15.8 59.4 22.0 24.5 28.1 11.6 14.8 20.5 21.1 48.4 35.8 74.2 42.6 16.2 14.7 26.8 33.8 21.3 17.6 29.5 52.4 65.6 21.5 49.5 24.8 44.4 68.4 25.1 22.3 17.4 24.8 17.7 25.0 21.1 80.5 28.2 18.3 106.3 197.8 87.9 27.6 54.9 65.4 24.7 20.7 112.2 15.3 40.4 28.1 34.1 33.2 29.3 61.7 19.3 19.3 72.5 16.5 14.3 57.7 16.4 30.2 15.2 17.0 38.0 24.1 64.9 17.4 31.4 10.5 0.5 6.2 6.3 6.3 28.9 11.3 8.6 35.3 14.4 24.2 18.8 0.7 0.4 1.2 30.9 3.2 9.2 7.3 6.1 2.5 7.8 8.5 5.8 7.0 4.7 7.1 2.9 5.4 6.4 11.4 6.4 8.6 3.3 11.9 23.7 32.3 13.1 14.2 1.2 15.3 11.6 3.3 10.0 10.5 9.2 0.0 11.7 7.3 6.7 7.9 11.4 29.3 3.9 10.9 7.7 4.9 41.3 2.5 9.3 23.6 8.9 5.6 5.8 7.0 24.7 6.4 12.1 11.1 3.3 3.5 11.3 2.0 8.8 24.9 11.1 8.7 9.4 21.4 0.0 9.3 1.4 2.1 1.5 2.9 7.1 11.2 4.5 6.1 29.7 2.8 15.8 3.1 0.2 6.6 13.5 10.0 31.3 36.4 17.8 23.9 10.1 8.6 21.4 20.8 22.8 RHPN1 "KIAA1929, ODF5, RHPN" ENSG00000158106 "Rhophilin Rho GTPase binding protein 1" Q8TCX5 8 143368876-143384221 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 20.1;thyroid gland: 20.4" "Cell type enhanced" "Detected in many" "Astrocytes: 47.0;Collecting duct cells: 38.6;Cone photoreceptor cells: 31.3;Respiratory ciliated cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 28.3;MOLT-4: 25.8;RPMI-8226: 19.0;T-47d: 44.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024288, HPA024671" Approved Approved Nucleoplasm NA NA "Cluster 43: Testis - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "HPA024288: AB_1856274, HPA024671: AB_1856275" "unprognostic (2.04e-1)" "unprognostic (3.71e-1)" "unprognostic (1.54e-2)" "unprognostic (2.20e-1)" "unprognostic (5.82e-2)" "unprognostic (6.38e-2)" "unprognostic (2.07e-3)" "unprognostic (3.12e-1)" "unprognostic (3.57e-1)" "unprognostic (1.02e-1)" "unprognostic (8.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.16e-2)" "unprognostic (1.24e-3)" "unprognostic (9.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-2)" 2.6 1.6 11.8 0.9 9.1 2.1 4.7 6.7 12.9 3.3 8.5 2.0 0.1 1.3 1.3 2.4 5.0 0.7 1.1 13.5 8.2 13.6 1.3 3.5 1.1 7.5 9.3 0.7 4.2 2.9 20.1 0.1 7.2 4.0 0.1 0.6 3.6 1.9 0.3 2.7 3.0 0.3 5.9 5.3 3.0 4.0 9.9 8.8 20.4 0.0 0.5 2.6 1.9 7.1 2.9 4.9 1.2 3.8 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.7 1.9 0.2 9.8 0.0 0.2 1.3 0.0 0.0 0.0 0.6 4.4 0.0 3.5 0.3 0.4 0.3 3.1 0.0 0.8 0.0 0.0 0.9 1.0 11.5 1.1 5.8 0.0 28.3 25.8 2.6 1.7 5.9 13.4 7.0 0.0 19.0 3.9 4.6 7.2 2.7 1.5 8.1 1.8 0.0 44.2 0.0 0.0 0.0 5.1 0.1 0.2 1.0 0.6 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.8 9.1 6.7 12.9 13.5 8.2 7.5 9.3 7.2 5.9 9.9 7.1 6.7 6.4 7.5 47.0 2.0 2.5 2.7 3.9 3.4 3.4 13.4 8.9 1.0 2.8 5.9 38.6 31.3 1.6 3.3 2.4 11.7 8.7 5.1 21.9 1.2 5.7 22.7 1.7 20.2 2.8 0.2 1.1 11.7 4.1 0.0 6.6 5.3 1.4 3.2 6.7 10.2 3.1 6.1 1.3 6.0 11.2 0.3 1.6 7.2 3.7 1.4 11.5 0.0 15.1 3.6 3.3 1.2 1.5 1.4 3.2 0.0 15.8 38.6 25.2 0.0 0.7 1.5 7.6 7.2 2.5 1.4 1.9 5.5 1.1 4.3 3.7 MAFA "hMafA, RIPE3b1" ENSG00000182759 "MAF bZIP transcription factor A" Q8NHW3 8 143419182-143430732 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skeletal muscle: 25.6" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 42.7;Skeletal myocytes: 12.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.2;MCF7: 1.9;RH-30: 1.2;SCLC-21H: 2.8;T-47d: 2.6;U-2 OS: 1.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 37: Myocytes - Muscle contraction" "unprognostic (5.92e-3)" "unprognostic (9.89e-3)" "unprognostic (2.81e-3)" "unprognostic (1.42e-8)" "unprognostic (1.75e-2)" "unprognostic (8.67e-2)" "unprognostic (6.08e-2)" "unprognostic (5.67e-2)" "unprognostic (4.41e-1)" "unprognostic (3.71e-1)" "unprognostic (1.37e-1)" "unprognostic (1.21e-1)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.00e-1)" "unprognostic (3.36e-1)" "unprognostic (3.38e-2)" 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.2 0.0 0.0 0.0 0.9 0.5 0.0 2.4 0.5 0.5 0.3 0.4 0.1 0.0 0.1 0.4 0.0 25.6 0.2 0.0 0.0 2.8 0.1 0.1 3.9 0.5 0.0 0.2 1.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.3 0.3 0.0 0.1 0.3 1.2 0.2 0.0 0.0 2.8 0.1 0.7 0.0 0.0 0.4 2.6 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.2 0.4 0.2 0.9 0.5 0.4 2.8 0.5 0.3 6.8 0.0 0.0 0.0 3.9 0.5 0.5 0.0 2.8 2.7 2.3 1.9 6.0 0.0 0.0 3.7 2.1 0.3 4.0 6.5 0.0 0.0 0.5 1.8 0.5 0.9 42.7 0.0 0.0 0.0 0.1 0.8 5.1 2.3 0.0 0.4 0.4 0.0 0.1 0.0 0.0 4.0 0.0 0.0 1.0 0.2 0.0 1.6 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 3.5 0.0 1.0 0.4 1.0 0.0 0.0 3.9 0.0 12.8 3.3 0.8 2.9 2.9 1.1 0.3 1.8 0.0 2.8 0.3 ZC3H3 "KIAA0150, ZC3HDC3" ENSG00000014164 "Zinc finger CCCH-type containing 3" Q8IXZ2 8 143437659-143541447 "Predicted intracellular proteins" "mRNA transport, Transport" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023658, HPA050577" Uncertain Approved Nucleoplasm NA NA "Cluster 10: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "HPA023658: AB_1858973, HPA050577: " "unprognostic (1.15e-1)" "unprognostic (7.74e-2)" "unprognostic (1.87e-2)" "unprognostic (6.77e-2)" "unprognostic (1.33e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.06e-4)" "unprognostic (2.18e-3)" "unprognostic (2.12e-1)" "unprognostic (1.30e-2)" "unprognostic (3.69e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (4.38e-7)" "unprognostic (3.59e-2)" "unprognostic (1.33e-1)" "unprognostic (5.67e-2)" "unprognostic (2.18e-1)" 16.4 12.7 6.0 5.6 6.1 17.2 14.4 6.3 9.4 11.8 2.7 13.4 11.7 12.3 1.0 14.6 11.3 2.2 11.4 6.6 3.6 25.0 45.9 14.5 5.0 6.3 4.7 12.0 10.5 2.9 8.2 3.6 6.4 12.1 1.5 1.9 11.0 3.5 21.1 16.9 21.5 2.6 3.7 19.1 11.8 19.4 6.2 5.3 14.0 2.9 2.5 12.2 12.0 6.8 11.3 16.1 5.1 12.4 3.1 3.6 13.7 6.4 4.5 8.0 6.5 8.8 10.3 8.0 11.2 5.3 4.3 12.9 4.1 6.6 1.7 16.7 14.2 10.0 10.6 14.2 7.6 5.0 8.9 8.0 6.1 6.6 4.7 3.7 5.9 7.6 17.1 14.5 3.3 29.3 24.1 9.7 9.4 9.2 26.0 13.9 4.1 25.6 5.9 6.8 13.1 8.7 12.4 10.9 7.1 2.6 17.5 9.4 8.2 7.0 21.1 15.4 11.3 13.2 9.4 6.8 9.1 11.6 7.8 6.5 4.6 6.3 3.9 5.5 4.5 3.2 4.6 4.8 3.7 2.7 5.8 4.8 9.1 2.2 3.6 3.2 3.4 5.4 6.0 6.1 6.3 9.4 6.6 3.6 6.3 4.7 6.4 3.7 6.2 6.8 6.9 0.0 2.3 10.7 8.4 7.0 3.4 4.5 5.7 7.3 5.1 3.4 1.4 4.3 3.4 5.5 8.4 7.9 4.0 14.2 1.9 6.5 8.8 5.6 6.1 5.5 10.7 12.8 9.8 7.3 9.4 5.4 20.4 7.2 5.7 28.1 5.0 13.2 8.5 5.0 9.9 11.2 6.1 9.8 6.0 7.9 5.3 10.9 3.6 6.5 6.4 6.1 7.2 4.0 10.5 7.6 2.3 5.7 8.4 4.4 16.7 11.2 3.5 7.5 13.1 4.0 5.8 22.8 14.8 6.3 8.7 12.3 7.2 3.8 9.0 5.5 GSDMD "DF5L, FLJ12150, GSDMDC1" ENSG00000104518 "Gasdermin D" P57764 8 143553207-143563062 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 226.7;Proximal enterocytes: 297.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004656, HPA044487" Uncertain Supported Nucleoplasm "Intracellular and membrane" NA NA 11000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "CAB004656: AB_426076, HPA044487: AB_2678957" "unprognostic (1.11e-2)" "unprognostic (8.44e-2)" "unprognostic (6.72e-2)" "unprognostic (4.00e-2)" "unprognostic (4.38e-2)" "unprognostic (1.10e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (7.20e-2)" "unprognostic (6.36e-2)" "unprognostic (4.66e-2)" "unprognostic (8.90e-2)" "prognostic unfavorable (1.43e-4)" "unprognostic (8.51e-3)" "unprognostic (1.60e-1)" "unprognostic (1.96e-1)" "unprognostic (6.77e-3)" 43.1 36.0 6.5 34.1 6.7 39.4 41.5 6.5 9.0 42.9 11.1 48.4 51.3 36.7 9.1 22.5 41.5 15.7 24.6 6.2 6.4 50.6 88.8 54.8 42.3 7.7 7.2 39.5 35.1 19.2 18.3 16.5 7.2 39.0 13.6 1.0 32.5 15.1 11.0 16.8 60.3 12.4 7.1 120.1 37.9 7.3 7.0 24.4 46.4 6.1 16.1 35.8 31.7 7.1 40.8 18.4 0.3 0.1 13.4 14.7 23.8 13.8 36.4 44.0 47.4 3.1 54.6 14.5 21.9 21.1 19.6 12.5 0.7 31.1 11.1 43.8 2.8 23.2 5.4 22.6 17.8 4.2 1.0 35.5 2.6 16.1 9.4 14.5 34.1 34.2 1.4 49.1 2.3 0.8 87.5 7.1 0.3 27.3 67.6 30.2 1.5 48.7 22.5 39.9 0.5 0.6 44.2 39.8 43.4 5.6 69.7 24.8 13.3 0.2 44.6 3.2 22.1 16.5 22.4 0.4 26.5 19.6 21.8 65.4 44.7 45.9 55.0 73.2 44.8 39.9 48.6 53.7 40.7 31.1 33.8 40.4 46.2 41.1 69.1 29.1 71.1 46.8 6.5 6.7 6.5 9.0 6.2 6.4 7.7 7.2 7.2 7.1 7.0 7.1 91.1 12.8 29.1 6.8 39.8 10.8 47.1 55.7 23.9 0.2 31.6 30.5 12.2 47.1 37.5 31.3 0.0 62.0 54.6 226.7 60.7 68.3 2.2 33.8 20.0 57.0 39.6 14.9 0.1 92.7 98.1 34.0 68.8 27.2 27.3 171.1 75.3 72.3 63.1 0.0 0.1 114.8 30.5 50.1 18.4 7.0 23.6 52.5 17.8 7.5 74.4 28.9 81.4 0.5 0.1 50.2 181.1 22.6 41.1 34.6 297.7 121.8 43.1 1.7 59.2 24.0 34.4 1.4 12.3 13.8 8.9 41.7 61.5 24.2 131.8 45.9 MROH6 C8orf73 ENSG00000204839 "Maestro heat like repeat family member 6" A6NGR9 8 143566192-143572772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 23.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 13.8;Hepatocytes: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 11.6;HaCaT: 13.6;OE19: 14.8;SK-BR-3: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA068049 Uncertain Approved Nucleoplasm NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA068049: AB_2685945" "unprognostic (2.10e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-3)" "unprognostic (2.26e-3)" "unprognostic (8.04e-2)" "unprognostic (8.96e-2)" "unprognostic (2.28e-1)" "unprognostic (1.73e-1)" "unprognostic (5.97e-2)" "unprognostic (2.81e-2)" "unprognostic (1.09e-2)" "unprognostic (9.04e-2)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (1.44e-1)" "unprognostic (9.16e-3)" "unprognostic (1.18e-1)" 2.5 3.1 1.1 0.5 1.2 1.7 2.1 1.2 1.4 6.5 1.0 4.5 2.0 2.4 0.1 23.4 2.4 0.7 1.4 1.2 0.9 3.7 7.4 4.0 0.3 1.2 1.2 3.2 1.1 0.2 1.9 0.2 1.1 2.8 0.0 0.1 4.2 0.4 0.9 13.9 5.0 0.1 1.0 4.6 2.9 5.8 1.2 0.3 1.7 0.1 0.7 3.3 8.5 1.0 11.6 2.0 0.2 0.4 0.7 0.7 0.5 0.5 0.4 0.5 0.2 0.4 6.0 1.1 0.6 0.2 0.0 13.6 0.0 2.7 0.0 1.2 1.2 1.3 4.3 0.3 0.6 0.5 1.1 0.7 0.7 0.0 0.0 0.0 0.2 0.4 0.6 0.7 0.0 2.8 0.6 0.3 0.0 14.8 1.1 0.7 0.4 1.1 0.7 1.1 0.2 0.3 0.6 30.0 0.7 0.0 1.3 0.9 0.0 0.4 3.9 0.7 1.2 0.5 0.4 0.3 0.5 6.8 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.2 1.2 1.4 1.2 0.9 1.2 1.2 1.1 1.0 1.2 1.0 4.0 0.0 4.7 3.9 1.6 2.8 2.2 1.4 4.0 1.4 7.2 4.3 1.5 7.2 2.7 9.2 0.0 1.0 3.7 13.8 1.9 1.3 0.0 1.5 2.9 2.4 1.8 6.1 1.4 0.7 3.4 3.0 6.6 3.0 1.3 3.6 1.1 13.4 5.2 1.7 1.3 4.5 0.0 8.1 3.7 1.3 4.7 6.0 3.6 0.0 3.3 3.5 4.1 0.5 0.3 7.2 6.0 2.6 3.1 2.1 7.3 2.3 0.9 0.3 0.0 2.8 2.3 0.7 7.6 3.2 2.6 1.0 2.6 2.3 8.2 2.8 NAPRT "NAPRT1, PP3856" ENSG00000147813 "Nicotinate phosphoribosyltransferase" Q6XQN6 8 143574785-143578649 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 63.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 597.2;Proximal tubular cells: 203.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 49.8;RPMI-8226: 73.4;SK-BR-3: 84.1" "Low region specificity" "Detected in all" "HPA023739, HPA024017, CAB068206, CAB068207" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 2300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB068206: AB_2665644, CAB068207: AB_2665681, HPA023739: AB_1854308, HPA024017: AB_1854309" "unprognostic (7.08e-2)" "unprognostic (1.55e-1)" "unprognostic (5.76e-3)" "unprognostic (2.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.30e-1)" "unprognostic (7.65e-2)" "unprognostic (2.19e-1)" "unprognostic (2.84e-1)" "unprognostic (1.08e-2)" "unprognostic (1.75e-1)" "unprognostic (4.13e-2)" "prognostic favorable (6.28e-4)" "unprognostic (6.02e-2)" "unprognostic (3.97e-1)" "unprognostic (2.28e-2)" "unprognostic (1.61e-2)" 15.7 13.6 4.1 6.3 4.7 21.9 14.6 3.9 8.7 15.8 4.6 22.2 61.4 9.7 1.7 37.1 10.6 5.8 10.8 4.3 4.8 15.7 63.1 13.8 6.6 5.4 4.1 9.6 12.4 5.0 6.0 5.4 4.0 11.3 3.9 0.2 29.2 10.5 10.1 27.9 47.3 2.9 4.4 19.4 22.5 10.5 4.7 4.1 9.8 4.6 5.2 13.2 18.1 5.6 14.8 7.2 0.6 1.4 3.2 2.0 4.0 0.7 7.5 4.5 1.7 5.6 34.3 1.8 7.8 0.5 0.0 25.6 1.8 34.6 0.4 4.3 12.1 16.7 25.5 1.9 42.5 2.1 14.8 3.2 16.6 0.3 0.0 0.1 18.1 32.9 21.5 8.8 0.1 11.1 6.7 8.0 5.6 49.8 4.2 13.8 0.3 73.4 16.0 2.0 7.4 0.9 9.1 84.1 30.7 0.6 2.1 20.3 3.8 0.9 10.1 8.0 2.9 0.8 0.8 3.1 1.8 41.8 16.1 6.9 11.4 14.1 2.9 12.7 1.9 2.0 4.4 1.9 6.7 1.3 1.3 2.4 10.6 0.8 23.0 6.9 1.9 5.8 4.1 4.7 3.9 8.7 4.3 4.8 5.4 4.1 4.0 4.4 4.7 5.6 50.6 35.3 23.1 7.5 16.2 0.0 64.9 0.0 24.5 12.1 18.3 14.7 10.0 54.3 9.3 75.4 18.8 48.8 21.8 88.0 68.4 62.7 44.2 18.5 26.0 32.7 10.9 63.8 3.8 54.3 74.8 20.6 100.9 26.8 7.6 21.7 49.6 117.4 80.6 16.8 3.2 70.4 0.0 89.7 0.0 59.8 32.0 55.0 0.0 7.5 108.9 23.7 28.8 1.5 2.8 111.7 124.6 21.8 12.7 44.2 597.2 203.7 1.5 13.4 13.1 15.8 16.5 41.7 16.0 35.9 0.0 56.2 17.2 29.7 100.9 73.9 EEF1D "EF-1D, FLJ20897" ENSG00000104529 "Eukaryotic translation elongation factor 1 delta" P29692 8 143579697-143599541 "Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis, Transcription, Transcription regulation" "DNA-binding, Elongation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045101, HPA051002" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA 1300000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Nucleoli fibrillar center" "HPA045101: AB_10963077, HPA051002: AB_2681305" "unprognostic (9.34e-2)" "unprognostic (2.37e-2)" "unprognostic (9.92e-2)" "unprognostic (1.63e-3)" "unprognostic (5.25e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.82e-4)" "unprognostic (8.56e-2)" "unprognostic (3.74e-1)" "unprognostic (2.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.58e-5)" "unprognostic (3.99e-2)" "unprognostic (2.06e-1)" "unprognostic (2.67e-2)" "unprognostic (2.14e-1)" 556.9 600.9 278.8 254.4 299.8 474.5 552.1 276.4 339.0 638.4 302.9 716.0 205.3 497.5 228.5 524.8 523.0 179.7 795.4 267.2 277.0 491.3 582.9 435.3 380.0 303.4 283.3 979.4 1349.3 160.2 328.0 147.2 292.4 609.2 148.3 67.1 577.0 201.9 916.1 615.8 505.9 179.9 281.5 609.6 634.3 288.1 281.7 338.7 504.0 433.0 307.3 538.2 554.0 322.1 454.8 644.8 284.2 246.0 251.0 307.0 314.2 344.2 438.4 536.7 424.0 886.7 420.0 345.5 352.2 386.6 160.4 441.8 295.3 556.0 231.7 274.8 487.6 340.6 1211.8 881.5 373.6 214.1 276.9 594.8 796.6 325.1 367.8 309.6 364.5 282.0 325.2 497.6 309.3 1456.4 838.7 539.7 300.3 580.3 852.3 367.2 204.4 681.0 466.3 757.9 280.0 301.6 300.1 726.3 762.5 174.1 544.3 535.7 285.2 309.9 914.8 465.5 757.5 335.2 142.9 380.2 348.4 431.6 275.3 268.2 535.1 259.6 880.1 503.5 1128.3 1400.1 1110.3 922.6 619.1 1461.9 1365.3 1110.3 408.6 864.7 458.9 874.2 1191.8 2020.0 278.8 299.8 276.4 339.0 267.2 277.0 303.4 283.3 292.4 281.5 281.7 322.1 652.3 163.5 415.9 47.7 1397.8 1846.0 1620.8 1277.4 1438.7 75.7 1568.2 2028.8 3.9 732.0 600.3 342.1 20.9 665.5 942.8 718.8 855.0 751.4 413.0 173.0 441.3 705.7 343.3 639.1 11.3 1793.7 822.0 699.2 520.9 263.8 446.1 931.0 871.7 792.9 799.6 79.1 13.0 971.5 526.9 1361.3 1492.3 1087.1 891.3 823.6 1085.1 17.8 1400.9 502.7 1071.1 15.6 30.2 938.4 799.5 633.1 1098.8 1566.2 998.9 1552.3 241.7 88.9 479.9 1005.6 844.4 34.0 142.2 969.5 1648.6 712.5 1297.8 573.3 870.0 1619.4 TIGD5 FLJ14926 ENSG00000179886 "Tigger transposable element derived 5" Q53EQ6 8 143597831-143603224 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 20.9;Theca cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "unprognostic (1.90e-1)" "unprognostic (7.91e-2)" "unprognostic (1.21e-1)" "unprognostic (5.24e-2)" "unprognostic (1.22e-1)" "unprognostic (2.87e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (2.79e-2)" "unprognostic (1.12e-1)" "unprognostic (6.72e-2)" "unprognostic (2.75e-3)" "unprognostic (3.16e-1)" "prognostic favorable (9.16e-5)" "unprognostic (1.44e-2)" "unprognostic (1.34e-1)" "unprognostic (2.32e-1)" "unprognostic (4.04e-1)" 2.1 2.9 1.8 0.2 1.6 0.1 2.1 4.0 2.0 3.0 0.5 3.1 0.4 3.2 0.1 3.5 3.0 0.2 3.6 1.5 1.6 3.0 2.3 1.7 0.3 2.1 2.0 4.0 5.9 0.7 3.8 0.1 1.7 3.0 0.1 0.1 2.7 0.3 4.4 3.7 2.7 0.1 1.5 3.6 3.0 1.5 1.7 0.2 3.0 0.4 0.2 3.2 2.5 2.0 0.9 1.5 0.4 1.2 0.6 0.6 0.6 0.5 0.4 0.5 0.4 0.5 0.6 1.7 2.7 0.4 0.5 1.2 0.4 0.4 0.0 5.9 1.8 1.0 1.7 0.2 1.1 0.4 1.4 0.6 1.1 0.3 0.5 0.7 0.4 0.4 1.2 0.2 0.2 1.6 2.9 1.7 0.6 1.0 2.9 1.1 0.3 0.8 0.5 0.6 1.4 1.8 1.1 0.9 1.2 0.1 2.6 1.2 0.7 1.0 0.8 1.0 3.5 0.9 0.4 0.2 0.6 0.7 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 1.6 4.0 2.0 1.5 1.6 2.1 2.0 1.7 1.5 1.7 2.0 5.0 3.2 1.3 0.7 3.8 1.7 5.4 0.9 1.2 16.0 6.3 4.6 5.9 4.3 1.3 5.5 20.9 1.4 4.9 5.1 0.0 2.3 1.0 4.0 8.1 4.4 0.0 4.0 0.8 1.8 1.3 4.2 2.0 5.5 1.3 15.4 4.6 2.6 3.4 16.8 1.1 3.6 0.0 3.2 0.8 0.7 7.8 3.0 0.0 1.0 3.2 10.0 6.2 0.5 0.4 3.6 1.7 4.5 1.0 4.9 3.3 2.2 1.1 15.1 0.0 10.6 4.2 0.8 1.2 2.4 1.0 1.8 3.5 29.3 5.1 3.8 PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 14.7;Ductal cells: 10.2;Exocrine glandular cells: 9.1;Extravillous trophoblasts: 11.8;Proximal tubular cells: 12.4;Theca cells: 14.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: AB_2685010, HPA069706: AB_2686178" "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.74e-1)" "unprognostic (2.44e-1)" "unprognostic (1.06e-2)" "unprognostic (2.30e-1)" "unprognostic (7.68e-3)" "unprognostic (1.79e-1)" "unprognostic (1.96e-1)" "unprognostic (2.26e-2)" "unprognostic (5.85e-2)" "unprognostic (5.44e-2)" "unprognostic (1.82e-2)" "unprognostic (3.64e-2)" "unprognostic (2.96e-1)" "unprognostic (3.54e-2)" "unprognostic (2.54e-1)" 5.0 9.7 2.8 0.4 2.9 0.6 5.2 2.7 3.3 5.1 1.0 4.2 0.5 5.2 1.1 7.1 6.0 0.8 3.9 2.9 1.6 9.7 17.2 3.8 0.9 2.3 2.2 5.1 9.2 0.6 10.0 0.4 2.7 8.7 0.6 0.7 5.8 0.5 3.0 4.0 4.1 0.4 1.5 5.9 5.5 7.0 2.7 0.4 8.4 0.3 0.7 4.4 3.8 2.1 3.2 4.0 1.6 2.5 1.8 0.6 2.0 3.0 1.4 2.9 1.9 2.9 2.6 6.2 2.1 2.0 1.1 2.6 2.0 4.0 1.1 3.0 5.3 3.7 2.2 2.0 0.6 1.9 1.0 0.8 1.9 3.1 1.9 1.2 0.7 3.7 4.3 3.1 1.9 7.2 3.0 1.7 2.1 4.5 10.4 2.8 1.8 4.3 3.4 2.2 5.3 1.4 3.6 4.9 1.6 0.8 6.4 2.0 0.9 2.9 4.0 3.4 3.1 2.5 0.8 4.2 2.6 2.0 1.9 0.2 0.9 0.0 1.1 0.6 1.2 1.3 0.8 0.8 0.6 4.7 1.1 1.0 0.1 1.3 0.7 3.0 0.9 0.6 2.8 2.9 2.7 3.3 2.9 1.6 2.3 2.2 2.7 1.5 2.7 2.1 2.9 3.2 3.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 8.8 7.7 0.0 0.0 0.6 14.7 0.0 5.1 1.6 0.0 3.9 10.2 0.0 6.8 6.6 1.9 0.0 0.0 0.0 9.1 11.8 2.9 0.0 5.2 0.0 5.5 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.8 0.0 0.0 12.4 4.4 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 2.5 1.2 14.7 0.0 0.0 GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 32.1;Cytotrophoblasts: 82.1;Extravillous trophoblasts: 156.4;Hofbauer cells: 69.9;Syncytiotrophoblasts: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 850000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Cytosol Nucleoplasm "HPA023361: AB_1858420" "unprognostic (1.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.62e-3)" "unprognostic (3.55e-2)" "unprognostic (2.90e-1)" "unprognostic (5.82e-2)" "unprognostic (2.48e-2)" "unprognostic (1.98e-1)" "unprognostic (8.62e-2)" "prognostic favorable (2.41e-4)" "unprognostic (6.62e-3)" "unprognostic (6.89e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (4.23e-2)" "unprognostic (2.78e-2)" "unprognostic (1.87e-2)" "unprognostic (3.27e-2)" 36.3 37.2 21.6 27.7 21.1 52.3 34.0 21.4 25.9 28.6 21.7 45.9 69.2 24.8 19.2 88.7 24.0 29.3 32.1 20.7 21.3 37.5 86.6 28.4 29.1 23.5 21.9 19.0 99.5 22.8 44.0 24.4 22.8 45.0 37.6 6.5 70.9 24.2 30.2 81.5 52.4 19.4 20.2 35.7 111.4 49.4 21.0 26.6 32.1 18.4 27.1 31.0 36.0 22.5 85.6 67.1 29.2 99.7 28.6 26.1 54.1 70.3 73.0 50.2 38.1 78.5 94.3 37.5 64.6 52.5 21.2 60.6 47.8 100.8 23.2 101.7 53.8 58.7 103.0 93.4 57.2 42.2 67.1 30.3 47.4 31.7 127.3 42.2 84.3 61.9 66.4 57.0 41.2 267.5 39.8 53.2 45.8 267.7 87.1 47.1 26.3 122.3 106.1 94.8 67.3 45.9 53.3 100.2 73.0 23.0 133.5 58.8 75.5 34.8 132.0 35.1 67.6 34.1 30.2 29.0 52.8 91.6 54.7 34.9 27.4 42.9 40.3 38.5 43.0 35.2 43.1 46.8 30.1 40.1 31.5 38.5 31.0 63.6 33.8 54.5 57.5 45.7 21.6 21.1 21.4 25.9 20.7 21.3 23.5 21.9 22.8 20.2 21.0 22.5 32.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 82.1 11.2 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 156.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 87.7 1.7 0.0 0.0 0.0 ZNF623 KIAA0628 ENSG00000183309 "Zinc finger protein 623" O75123 8 143636019-143656418 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "PC-3: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044372 Uncertain Approved Nucleoplasm NA NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Nucleoplasm "HPA044372: AB_10966790" "unprognostic (1.06e-3)" "unprognostic (1.38e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.44e-1)" "unprognostic (8.67e-2)" "unprognostic (4.00e-3)" "unprognostic (6.95e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (1.82e-1)" "unprognostic (5.21e-2)" "unprognostic (8.03e-2)" 5.8 5.0 2.5 1.8 2.3 0.6 5.5 1.8 3.0 7.4 1.2 7.4 2.3 7.0 1.7 6.2 6.6 1.5 6.0 2.6 2.7 5.2 5.7 5.2 2.3 2.2 2.1 8.5 5.4 2.8 5.9 1.8 2.5 5.9 2.0 1.7 6.0 1.3 7.2 7.8 6.4 2.1 1.5 6.8 5.4 7.2 2.7 2.1 5.2 1.8 1.9 7.6 6.5 2.3 3.0 6.9 2.6 2.5 4.1 8.0 2.5 2.9 3.8 4.7 3.3 2.4 2.5 1.8 3.6 6.5 3.2 1.9 3.0 1.9 3.7 5.1 2.3 7.5 7.3 2.2 3.2 1.7 2.1 3.3 3.8 2.0 8.7 5.1 3.3 4.9 6.1 3.3 3.4 6.6 5.8 2.4 3.4 3.7 18.3 4.0 2.3 2.8 2.6 4.0 6.4 6.2 11.9 2.4 4.0 2.6 5.4 5.2 1.5 4.4 1.5 1.8 2.4 1.9 2.3 2.8 3.2 2.8 3.6 1.1 0.2 0.4 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.2 0.5 0.5 0.4 0.2 2.5 2.3 1.8 3.0 2.6 2.7 2.2 2.1 2.5 1.5 2.7 2.3 4.6 6.4 3.9 3.9 5.8 1.7 3.1 1.6 7.4 5.9 4.4 4.2 10.3 7.2 1.5 7.3 6.2 5.9 4.7 5.8 3.9 5.9 5.4 3.0 8.1 5.8 5.4 9.9 7.5 3.8 6.0 5.6 4.6 5.0 1.3 9.2 7.1 6.6 5.8 15.2 5.3 5.3 2.0 6.6 2.4 4.5 8.4 4.6 3.6 4.7 8.3 7.2 7.2 5.5 5.4 4.4 2.3 13.9 2.8 4.5 5.4 3.9 1.3 7.0 19.7 8.2 5.1 10.8 13.9 6.2 2.6 4.8 5.8 5.8 5.2 1.7 ZNF707 ENSG00000181135 "Zinc finger protein 707" Q96C28 8 143684452-143713898 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 19.7;NK-cells: 12.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA044991 Approved Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "HPA044991: AB_10961134" "unprognostic (5.12e-2)" "unprognostic (5.65e-2)" "unprognostic (3.86e-2)" "prognostic unfavorable (6.79e-4)" "unprognostic (1.73e-1)" "unprognostic (5.91e-2)" "unprognostic (2.94e-2)" "unprognostic (1.65e-1)" "unprognostic (8.66e-2)" "unprognostic (1.11e-1)" "unprognostic (6.98e-2)" "unprognostic (5.07e-2)" "unprognostic (2.30e-2)" "unprognostic (1.14e-2)" "unprognostic (5.23e-1)" "unprognostic (2.47e-2)" "unprognostic (4.08e-2)" 3.3 3.3 1.0 1.8 1.1 1.7 3.4 0.7 1.3 4.0 1.3 3.5 1.5 3.8 1.8 3.7 3.3 1.3 3.0 0.9 0.9 4.9 3.4 3.9 2.6 1.0 0.9 2.9 4.2 1.7 3.7 1.1 0.9 4.1 0.8 0.9 3.8 1.1 1.8 5.9 4.2 1.0 0.7 8.0 3.5 7.4 1.1 2.1 4.5 1.4 1.8 3.6 3.5 1.3 1.7 2.2 2.4 2.6 2.4 2.2 2.4 2.5 1.7 2.7 1.3 1.5 2.4 1.6 2.7 1.6 1.2 2.1 2.5 2.9 1.7 3.3 0.9 4.3 5.7 2.3 1.6 1.1 2.0 2.3 3.3 3.6 2.2 2.3 2.4 2.0 2.0 1.6 0.7 3.6 4.5 1.3 0.1 1.8 3.8 3.0 1.5 1.6 1.4 1.5 1.8 2.1 3.3 2.3 3.0 1.6 3.0 2.3 3.8 1.6 5.5 2.0 3.8 3.3 1.4 0.7 2.3 2.4 1.2 0.3 0.2 0.4 0.5 0.1 0.4 0.2 0.3 0.3 0.2 0.1 0.2 0.3 0.3 0.9 0.1 0.3 0.4 0.2 1.0 1.1 0.7 1.3 0.9 0.9 1.0 0.9 0.9 0.7 1.1 1.3 2.4 0.0 1.5 2.9 3.6 2.8 2.7 2.4 5.2 2.7 2.2 1.8 1.9 0.0 2.0 3.7 0.0 2.1 5.6 2.8 3.9 1.9 19.7 1.4 1.8 1.5 0.0 0.4 1.9 1.3 2.5 1.6 2.0 2.5 1.3 3.6 3.3 1.1 1.9 1.7 1.2 1.8 0.0 3.5 4.3 5.3 1.2 2.4 0.0 1.9 5.2 0.6 12.3 1.0 1.2 1.7 2.1 2.2 4.3 2.2 1.9 0.9 1.6 3.4 6.6 1.0 1.5 4.3 3.1 2.3 3.1 2.6 4.8 2.6 1.6 2.2 CCDC166 ENSG00000255181 "Coiled-coil domain containing 166" P0CW27 8 143706694-143708109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 4.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 27.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA025058 Uncertain NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "HPA025058: AB_2671717" "unprognostic (2.65e-1)" "unprognostic (3.64e-1)" "unprognostic (6.18e-2)" "unprognostic (4.97e-1)" "unprognostic (1.67e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716340-143722458 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 54.9;fallopian tube: 46.7" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 62.5;Respiratory ciliated cells: 107.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.6;HeLa: 20.7;MCF7: 14.3;T-47d: 14.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 1.6 0.1 3.3 0.2 4.0 0.0 1.9 1.7 8.1 6.9 54.9 1.0 0.3 2.5 2.4 1.1 46.7 0.2 0.6 5.0 3.6 10.5 0.3 12.1 0.4 10.2 14.5 0.9 4.4 9.4 6.9 0.3 7.0 2.2 0.2 0.0 2.2 1.7 0.1 4.0 0.8 0.4 6.6 0.7 0.8 11.4 6.4 1.1 16.1 0.0 0.2 0.5 2.1 3.0 0.4 0.6 1.9 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.5 9.6 0.0 1.6 0.0 0.0 5.5 0.1 0.2 0.0 1.0 2.0 0.0 20.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.2 3.4 0.0 0.0 14.3 0.0 0.0 2.5 1.2 1.2 0.0 3.7 0.5 1.0 1.6 3.6 5.1 0.0 3.3 0.0 0.2 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 1.7 8.1 5.0 3.6 10.2 14.5 7.0 6.6 6.4 3.0 0.1 0.0 6.4 0.0 0.1 0.4 0.3 5.7 0.0 0.0 1.0 1.3 0.7 0.0 11.8 0.0 0.0 0.0 0.0 0.1 0.0 1.1 13.8 62.5 0.5 0.3 0.0 0.0 0.2 0.0 0.7 0.8 0.0 1.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.6 16.2 0.0 0.0 11.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 1.4 107.9 0.0 0.0 0.4 2.2 2.3 0.9 0.0 0.3 0.1 0.2 0.1 0.3 0.1 FAM83H FLJ46072 ENSG00000180921 "Family with sequence similarity 83 member H" Q6ZRV2 8 143723933-143738234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 70.5;skin 1: 34.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 58.7;hTCEpi: 59.8;MCF7: 118.2;OE19: 62.4;RT4: 70.1;T-47d: 58.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024505, HPA024604" Enhanced Approved Cytosol NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "HPA024505: AB_1848417, HPA024604: AB_1848418" "unprognostic (3.80e-2)" "unprognostic (3.75e-3)" "unprognostic (6.87e-2)" "unprognostic (1.63e-2)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.93e-1)" "unprognostic (2.40e-1)" "unprognostic (2.24e-3)" "unprognostic (3.95e-2)" "unprognostic (9.69e-3)" "prognostic favorable (4.42e-4)" "unprognostic (5.54e-1)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" 2.1 4.0 1.9 2.1 1.7 0.5 4.4 1.2 2.2 11.5 2.6 9.8 8.4 0.8 3.3 70.5 4.7 3.3 0.8 2.0 1.1 11.8 13.5 6.3 0.9 1.6 2.4 0.3 13.9 7.9 5.9 3.5 1.5 7.2 4.3 1.1 17.1 3.8 0.1 34.9 9.1 0.3 1.3 1.7 11.0 2.8 1.5 1.5 14.1 0.0 4.0 8.3 23.2 2.2 47.0 28.3 0.3 0.1 0.1 0.0 16.6 4.0 0.0 2.0 0.7 25.8 53.4 0.0 6.1 1.0 0.0 56.1 3.5 51.9 0.9 0.0 0.2 1.5 58.7 18.3 4.3 0.6 1.7 2.9 59.8 0.2 15.0 0.8 0.0 4.2 22.2 0.1 0.0 118.2 0.8 0.4 4.8 62.4 15.3 0.1 0.1 6.0 16.5 70.1 7.1 0.2 38.3 53.8 7.8 7.5 58.2 8.2 0.3 0.1 7.2 3.9 0.2 0.0 0.0 0.2 0.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.7 1.2 2.2 2.0 1.1 1.6 2.4 1.5 1.3 1.5 2.2 0.1 32.1 16.5 0.7 0.6 22.8 17.7 21.9 6.8 2.0 18.2 14.0 4.6 14.3 18.9 29.5 2.1 12.8 0.5 38.5 3.9 22.0 1.2 11.4 2.9 1.0 14.4 0.0 1.3 25.9 17.8 1.6 25.0 25.9 0.0 5.4 0.7 25.5 4.7 10.1 0.5 24.3 16.2 2.8 0.8 0.7 0.0 1.3 1.8 0.0 2.8 6.6 2.1 0.5 0.1 42.7 27.2 0.4 0.4 26.4 23.6 7.0 17.4 2.0 0.0 0.2 1.9 1.7 1.0 38.9 26.9 14.6 0.9 1.2 27.8 33.9 IQANK1 ENSG00000203499 "IQ motif and ankyrin repeat containing 1" A8MXQ7 8 143734139-143790645 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 41.2;skin 1: 28.7" "Cell type enhanced" "Detected in some" "Breast glandular cells: 8.4;Breast myoepithelial cells: 6.3;Collecting duct cells: 7.3;Cytotrophoblasts: 8.8;Endometrial ciliated cells: 23.2;Extravillous trophoblasts: 6.0;Respiratory ciliated cells: 12.4;Syncytiotrophoblasts: 10.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 26.5;HaCaT: 29.4;hTCEpi: 35.4;MCF7: 72.3;OE19: 68.6;RT4: 30.3;SK-BR-3: 30.0;T-47d: 64.4" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "unprognostic (1.45e-3)" "unprognostic (3.38e-1)" "unprognostic (7.46e-2)" "unprognostic (4.94e-3)" "unprognostic (4.31e-3)" "unprognostic (1.98e-1)" "unprognostic (5.88e-2)" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (1.15e-2)" "unprognostic (2.22e-3)" "unprognostic (3.29e-2)" "unprognostic (4.49e-3)" "unprognostic (1.42e-2)" "unprognostic (1.47e-1)" "unprognostic (1.79e-1)" "unprognostic (9.40e-2)" 0.2 0.3 0.8 0.6 1.2 0.8 6.1 1.2 1.0 8.3 2.2 1.8 1.3 0.8 21.5 41.2 13.6 1.3 0.2 1.1 0.4 3.0 0.5 3.5 0.2 1.5 2.9 0.2 4.7 3.3 1.9 3.5 1.0 7.2 2.4 1.9 8.0 2.0 0.3 28.7 0.9 0.2 0.7 0.3 4.1 8.4 0.6 0.6 2.6 0.0 3.9 6.3 18.5 1.0 17.6 1.1 0.2 0.8 0.1 0.2 19.5 0.3 0.0 0.1 0.2 9.2 26.5 0.1 2.0 0.1 0.1 29.4 0.9 3.4 0.2 0.2 0.8 0.1 2.8 2.1 0.5 0.2 0.2 0.3 35.4 0.2 0.7 0.4 0.0 0.6 1.3 0.2 0.0 72.3 0.1 0.2 1.5 68.6 1.1 0.2 0.1 0.6 1.9 30.3 9.8 0.2 2.6 30.0 1.1 2.3 64.4 0.4 0.2 0.3 1.0 0.5 0.1 0.5 0.2 0.2 0.1 0.3 0.5 0.8 0.3 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.1 0.1 1.4 0.2 0.2 0.2 0.0 0.0 0.8 1.2 1.2 1.0 1.1 0.4 1.5 2.9 1.0 0.7 0.6 1.0 0.1 0.0 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 8.4 6.3 0.0 0.0 3.7 7.3 0.0 8.8 0.0 0.0 0.0 2.0 0.0 23.2 0.7 0.3 0.0 0.0 0.0 1.6 6.0 0.4 0.0 5.2 1.3 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 1.3 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.1 0.2 0.0 0.0 SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" 18.7 17.1 11.5 7.2 10.8 5.6 23.6 6.0 10.4 45.6 0.0 32.3 9.1 24.7 0.9 100.5 26.0 3.4 24.6 8.7 2.7 27.7 25.4 21.3 4.0 10.7 8.1 23.0 38.8 5.2 24.8 5.0 5.9 28.4 3.4 1.0 40.2 5.2 54.3 68.3 26.5 2.0 4.9 22.9 30.0 26.4 9.0 3.0 24.6 1.7 3.9 27.8 52.6 15.3 55.7 33.1 12.7 20.5 5.1 6.9 33.0 30.9 5.3 11.2 9.1 15.3 29.8 24.2 39.7 7.2 4.6 52.4 7.9 32.9 1.7 30.8 58.5 24.6 30.5 26.1 10.8 13.0 14.8 5.1 29.9 9.4 5.5 5.1 11.5 19.8 42.2 6.4 7.5 93.0 38.1 26.9 15.7 25.0 55.1 44.5 10.6 25.0 5.6 45.5 29.6 27.1 31.4 30.5 33.6 4.5 41.5 28.2 25.7 10.1 64.1 25.2 44.7 31.6 31.0 23.8 13.1 9.5 19.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 10.8 6.0 10.4 8.7 2.7 10.7 8.1 5.9 4.9 9.0 15.3 12.3 0.0 9.9 33.0 4.4 8.5 5.0 10.2 13.6 11.3 16.8 17.0 11.1 11.5 8.3 14.7 14.6 11.0 9.7 28.7 3.9 8.6 1.5 14.0 7.7 7.8 13.8 13.7 5.0 9.4 6.3 7.3 29.6 27.3 0.0 17.9 3.6 8.8 6.5 5.0 6.2 17.8 18.3 6.0 4.1 0.7 9.0 6.6 8.8 6.5 5.0 10.0 5.2 12.1 15.2 11.5 22.8 9.8 5.6 9.3 16.9 4.5 9.9 16.0 13.1 12.0 8.7 9.4 10.0 19.9 10.7 5.1 7.3 8.0 23.2 7.1 PUF60 "FIR, RoBPI, SIAHBP1" ENSG00000179950 "Poly(U) binding splicing factor 60" Q9UHX1 8 143816344-143829352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "DNA-binding, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 332.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045733, HPA052096, HPA059714" Enhanced Enhanced Nucleoplasm NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "HPA045733: AB_10960503, HPA052096: AB_2681722, HPA059714: AB_2684110" "unprognostic (3.49e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (4.05e-2)" "unprognostic (1.81e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-2)" "unprognostic (4.34e-3)" "unprognostic (2.64e-2)" "unprognostic (1.07e-2)" "unprognostic (1.75e-1)" "unprognostic (5.45e-2)" "unprognostic (2.36e-2)" "unprognostic (2.64e-2)" "unprognostic (7.00e-2)" "unprognostic (2.28e-2)" "unprognostic (3.42e-2)" 71.6 73.5 7.9 11.0 7.6 39.6 75.5 8.1 22.9 71.4 5.3 84.8 22.3 84.9 5.9 84.9 76.3 7.3 88.5 7.8 15.4 82.8 124.3 64.0 17.7 12.2 11.6 57.2 62.9 11.7 71.0 19.2 14.1 67.2 5.8 1.3 63.3 17.8 125.5 108.7 69.5 10.5 7.3 72.3 73.2 70.8 14.5 15.9 59.8 9.0 9.7 74.5 68.6 12.4 95.7 211.5 36.7 31.3 16.6 15.6 62.7 74.4 27.4 70.3 75.1 95.4 103.9 89.4 71.2 58.9 52.8 83.0 86.5 91.4 3.6 91.4 147.7 110.2 117.0 106.3 60.4 38.5 70.0 45.4 61.8 89.8 26.9 21.1 69.0 92.1 88.7 37.4 20.5 332.5 156.1 26.4 77.8 63.3 191.6 84.2 42.9 91.8 19.5 91.8 71.5 80.3 101.6 40.4 77.7 9.1 116.7 21.4 79.0 72.9 176.2 85.7 98.6 66.7 103.9 109.7 70.7 73.3 71.9 90.8 112.6 99.8 129.0 133.7 139.3 116.8 103.1 128.6 127.1 135.9 98.6 113.1 58.8 132.6 137.6 76.8 139.0 193.9 7.9 7.6 8.1 22.9 7.8 15.4 12.2 11.6 14.1 7.3 14.5 12.4 70.2 38.5 46.4 21.5 64.7 107.7 102.1 197.4 65.4 62.8 51.3 67.9 63.7 51.5 103.0 29.5 29.2 146.6 56.4 98.0 92.0 110.7 20.5 65.6 55.3 67.3 66.9 65.0 8.2 89.8 134.3 68.4 74.9 60.3 55.8 75.0 41.7 76.8 101.1 43.7 8.3 75.9 118.0 44.0 62.3 47.8 64.0 52.3 90.7 6.5 105.2 182.6 81.4 9.5 23.7 98.2 91.4 59.0 52.7 83.0 91.9 118.1 85.4 64.8 65.7 57.1 122.9 104.2 128.5 63.1 107.1 173.3 74.2 99.3 97.7 81.2 NRBP2 DKFZp434P086 ENSG00000185189 "Nuclear receptor binding protein 2" Q9NSY0 8 143833583-143840973 "Enzymes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 134.2;Oligodendrocytes: 120.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020944, HPA029051, HPA029052" Approved Approved Cytosol NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "CAB020944: , HPA029051: AB_2672886, HPA029052: AB_10602714" "unprognostic (1.84e-1)" "unprognostic (4.66e-2)" "unprognostic (2.54e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (2.00e-2)" "unprognostic (4.03e-1)" "unprognostic (2.86e-1)" "unprognostic (3.97e-1)" "unprognostic (1.08e-1)" "unprognostic (2.24e-1)" "unprognostic (2.47e-2)" "prognostic unfavorable (2.01e-5)" "unprognostic (3.86e-2)" "unprognostic (3.98e-1)" "unprognostic (4.56e-2)" "unprognostic (2.04e-1)" 18.8 9.6 21.4 6.4 35.9 1.6 18.4 35.6 28.7 15.1 12.6 28.2 7.6 17.3 7.4 9.5 17.6 10.3 15.1 24.9 25.8 18.1 32.3 16.6 4.5 49.6 35.7 13.4 10.7 8.9 14.5 5.7 47.1 19.6 5.6 7.4 19.7 12.6 6.9 17.7 11.1 11.7 30.6 7.1 14.0 6.9 36.4 3.9 15.8 7.1 3.4 14.2 14.0 48.5 10.2 12.9 11.4 14.0 16.5 25.6 2.6 18.7 9.0 7.2 10.3 3.1 8.8 1.1 5.3 24.1 5.2 15.5 7.0 6.6 3.2 12.4 4.7 2.0 36.0 5.3 18.1 0.0 4.1 30.3 15.5 3.1 3.5 22.4 10.5 3.4 6.7 12.7 15.2 3.5 0.8 0.4 3.7 10.1 5.5 3.4 10.0 4.5 8.9 3.1 3.9 7.2 25.3 13.3 10.1 5.9 18.7 0.8 22.5 4.6 12.5 20.4 6.8 6.3 0.5 0.3 22.8 4.1 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 35.9 35.6 28.7 24.9 25.8 49.6 35.7 47.1 30.6 36.4 48.5 15.1 44.8 13.7 134.2 2.0 9.2 6.2 5.2 5.7 15.4 16.3 23.2 9.9 41.5 10.4 11.0 14.6 0.9 3.2 9.2 0.0 4.3 0.5 8.1 15.2 10.4 9.0 0.0 41.8 4.0 1.0 11.2 15.3 14.1 0.0 8.5 7.5 41.7 2.8 16.8 32.7 8.4 16.2 5.7 4.6 1.2 28.9 4.5 10.6 22.5 3.9 17.7 3.1 30.2 120.7 5.4 3.6 21.4 2.3 7.1 3.9 4.4 7.0 11.4 13.1 14.2 18.3 1.2 3.3 4.7 9.1 0.8 4.4 7.2 6.2 5.0 EPPK1 EPIPL1 ENSG00000261150 "Epiplakin 1" P58107 8 143857324-143878467 "Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 16.1" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 137.1;Suprabasal keratinocytes: 274.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 14.3;EFO-21: 13.3;HaCaT: 13.8;HeLa: 26.8;MCF7: 20.2;SK-BR-3: 9.3" "Not detected" "Not detected" "HPA066808, HPA067357, HPA069333" Approved Enhanced "Intermediate filaments" NA NA 1200000 "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Intermediate filaments" "HPA066808: AB_2685726, HPA067357: AB_2685826, HPA069333: AB_2686123" "unprognostic (1.42e-1)" "unprognostic (9.30e-2)" "unprognostic (5.89e-2)" "prognostic unfavorable (5.52e-5)" "unprognostic (2.85e-2)" "unprognostic (5.86e-3)" "unprognostic (4.90e-2)" "unprognostic (8.73e-2)" "unprognostic (9.60e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.35e-1)" "unprognostic (1.97e-3)" "unprognostic (5.94e-3)" "unprognostic (4.35e-1)" "unprognostic (3.68e-3)" "unprognostic (5.08e-3)" 0.2 0.0 0.4 0.3 0.4 0.1 0.9 3.9 0.5 0.5 1.3 3.3 2.1 2.4 0.3 1.7 2.0 0.2 0.1 0.8 0.6 1.2 0.3 0.9 0.1 2.5 2.7 0.0 0.7 0.2 0.2 0.2 1.7 1.4 0.6 0.0 2.2 1.4 0.2 16.1 2.7 0.9 1.6 1.2 2.1 1.8 0.7 0.1 0.2 0.0 0.2 1.8 0.9 0.4 7.9 0.1 0.1 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 7.4 0.5 0.0 13.3 0.0 0.0 13.8 1.4 0.1 0.0 0.0 3.4 0.0 26.8 4.6 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 20.2 0.0 0.0 1.4 1.8 0.0 0.0 0.1 0.0 0.0 4.9 2.3 0.0 2.2 9.3 0.0 1.2 7.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 3.9 0.5 0.8 0.6 2.5 2.7 1.7 1.6 0.7 0.4 0.7 19.2 9.2 1.0 1.1 137.1 20.3 8.2 8.0 0.6 32.7 25.0 27.9 11.5 4.4 14.7 0.0 2.5 0.0 48.1 0.0 11.3 0.5 12.6 0.5 3.2 6.0 0.0 0.3 14.7 0.3 2.4 12.2 10.1 0.0 0.6 0.7 4.4 0.3 0.0 0.0 14.5 12.2 0.0 8.2 0.3 0.0 0.4 16.0 0.0 0.0 0.6 0.0 0.0 0.1 31.9 21.7 0.0 0.2 8.6 28.2 7.0 24.2 0.2 0.0 0.0 5.2 1.5 1.0 10.6 274.3 6.2 1.2 0.1 28.4 31.5 PLEC "EBS1, PCN, PLEC1, PLTN" ENSG00000178209 Plectin Q15149 8 143915153-143976734 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant, Epidermolysis bullosa, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 256.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 257.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "PC-3: 384.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003847, HPA025967, HPA029906" Enhanced Supported "Intermediate filaments,Focal adhesion sites,Cytosol" NA NA 7400000 "Cluster 39: Non-specific - mRNA processing" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Intermediate filaments, Cytosol" "Focal adhesion sites" "CAB003847: AB_562198, HPA025967: AB_10601671, HPA029906: AB_10602279" "unprognostic (1.02e-1)" "unprognostic (1.37e-3)" "prognostic unfavorable (4.29e-4)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.05e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.72e-3)" "unprognostic (1.13e-2)" "unprognostic (2.85e-3)" "unprognostic (5.48e-2)" "prognostic unfavorable (7.98e-6)" "unprognostic (2.30e-1)" "unprognostic (4.04e-2)" "unprognostic (6.58e-2)" "unprognostic (5.58e-3)" 41.8 30.9 44.2 22.6 25.4 43.2 37.9 20.4 39.7 57.4 6.7 58.0 21.1 55.2 8.5 59.7 47.9 22.8 78.9 42.2 31.0 30.0 31.3 49.2 22.1 48.5 28.6 47.1 27.6 8.1 33.0 18.3 30.8 49.5 13.0 3.9 42.9 19.8 256.5 83.1 53.8 27.7 28.8 46.1 49.1 15.3 43.2 14.4 25.7 74.7 15.8 56.5 55.7 25.9 92.6 247.3 15.1 20.3 31.6 66.9 62.8 125.9 49.3 32.3 18.7 39.2 88.5 8.9 82.9 179.7 54.6 98.9 10.3 162.6 13.3 58.7 10.0 24.9 268.0 34.0 54.0 9.6 26.1 71.8 40.7 84.6 164.2 28.3 43.0 7.6 16.2 25.9 39.7 175.3 5.1 19.8 12.2 29.4 384.8 1.8 46.2 24.6 67.7 147.7 16.6 16.8 217.4 50.0 21.1 21.7 55.7 12.4 125.7 117.8 217.3 110.6 155.1 4.7 3.7 6.3 106.9 15.2 176.2 0.0 2.0 0.1 0.6 1.7 1.3 0.6 1.2 0.9 1.6 0.6 0.8 0.5 0.4 0.3 1.2 1.3 1.4 2.0 44.2 25.4 20.4 39.7 42.2 31.0 48.5 28.6 30.8 28.8 43.2 25.9 83.8 28.9 15.6 78.0 27.0 108.0 53.1 62.9 50.7 15.8 29.4 27.9 39.3 31.5 42.9 40.5 25.0 34.4 27.1 257.8 0.0 39.3 1.4 39.4 52.6 68.2 32.2 11.8 47.3 20.2 32.1 45.7 170.2 57.3 8.2 14.4 63.1 69.0 35.2 30.3 36.5 79.9 10.2 67.5 100.4 5.0 44.4 61.2 33.8 27.2 54.9 11.2 15.5 14.6 3.4 157.8 194.1 74.9 39.3 144.9 124.9 4.6 50.3 10.8 6.6 42.1 61.5 1.2 7.1 72.2 76.7 69.0 35.0 18.8 61.6 121.0 PARP10 "ARTD10, FLJ14464" ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028122, HPA052427" Approved Supported "Nucleoli rim,Golgi apparatus,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli rim" "Golgi apparatus, Cytosol" "HPA028122: AB_10601979, HPA052427: AB_2681828" "unprognostic (9.80e-3)" "unprognostic (5.89e-2)" "unprognostic (2.63e-3)" "unprognostic (9.10e-2)" "unprognostic (1.74e-2)" "unprognostic (1.46e-2)" "unprognostic (7.37e-2)" "unprognostic (3.61e-1)" "unprognostic (9.05e-2)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (4.69e-3)" "unprognostic (1.09e-3)" "unprognostic (4.17e-2)" "unprognostic (8.69e-2)" "unprognostic (5.30e-3)" 25.2 34.9 10.0 36.3 10.6 23.7 24.6 9.8 13.2 31.8 10.4 33.2 28.4 29.1 3.7 21.5 35.7 9.9 13.8 9.0 10.4 38.4 39.7 34.7 35.8 16.0 11.0 40.6 21.7 6.2 26.0 10.2 12.5 35.7 4.9 6.4 38.3 16.6 18.3 23.1 35.4 7.3 13.3 61.2 25.6 35.4 12.3 34.2 29.4 4.5 10.6 17.8 25.1 11.9 17.8 1.8 1.2 3.3 8.4 7.3 9.3 3.0 3.7 18.7 21.0 0.9 29.6 21.9 39.8 9.2 21.4 6.7 0.4 10.1 0.8 49.5 0.1 24.1 10.8 11.0 7.8 9.5 27.7 4.7 9.9 9.3 3.8 2.1 2.9 30.6 0.4 16.9 3.7 21.4 33.4 16.5 1.0 0.2 13.9 30.8 3.5 29.4 7.7 21.6 1.0 1.1 19.8 2.0 38.8 0.4 22.0 13.9 13.1 9.6 14.2 16.4 10.9 28.4 18.3 5.1 13.9 31.6 5.3 0.0 2.4 3.6 4.4 2.8 2.7 1.1 2.1 3.6 2.3 2.0 1.5 2.4 1.0 1.8 2.8 16.5 1.5 3.5 10.0 10.6 9.8 13.2 9.0 10.4 16.0 11.0 12.5 13.3 12.3 11.9 22.3 3.2 5.2 10.4 19.1 7.6 8.2 10.7 17.6 5.7 12.3 16.0 3.2 7.2 6.3 9.2 14.6 2.2 42.2 20.5 1.9 9.2 6.2 12.0 12.7 10.7 19.2 5.7 0.4 5.6 4.0 12.7 23.9 13.3 19.1 25.9 9.3 21.1 12.0 0.0 0.6 17.3 6.1 16.6 6.8 7.9 15.8 21.4 7.2 12.2 25.8 13.4 34.0 4.5 1.0 6.5 13.8 11.3 15.2 4.5 22.0 25.1 6.7 20.4 6.6 11.7 13.4 19.6 9.1 10.4 4.7 1.4 27.0 17.7 16.4 4.0 GRINA "HNRGW, LFG1, NMDARA1, TMBIM3" ENSG00000178719 "Glutamate ionotropic receptor NMDA type subunit associated protein 1" Q7Z429 8 143990056-143993415 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 432.6;monocytes: 355.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036980, HPA036981" Approved Approved "Nucleoli fibrillar center,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 3: Monocytes - Immune response regulation" "Nucleoli fibrillar center" Cytosol "HPA036980: AB_10696791, HPA036981: AB_10962980" "unprognostic (2.73e-3)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (1.12e-1)" "unprognostic (7.01e-3)" "unprognostic (3.72e-2)" "unprognostic (1.69e-1)" "unprognostic (1.35e-2)" "unprognostic (2.32e-1)" "unprognostic (6.70e-2)" "unprognostic (8.19e-2)" "unprognostic (3.13e-3)" "unprognostic (1.01e-3)" "unprognostic (1.55e-1)" "unprognostic (9.43e-2)" "unprognostic (6.75e-2)" "unprognostic (5.72e-2)" 273.1 218.3 154.1 109.0 147.4 215.1 236.4 143.9 226.4 178.9 99.4 144.9 72.1 137.8 79.7 134.2 149.0 74.5 154.8 158.9 149.8 200.8 447.1 233.9 77.7 151.6 155.6 152.7 97.2 144.4 127.7 86.2 160.5 176.0 33.2 180.7 116.7 181.7 145.4 167.1 138.1 75.1 152.1 311.3 104.6 269.4 163.1 58.5 187.4 57.4 55.2 162.1 139.3 140.2 79.3 155.9 76.4 129.5 392.6 196.9 114.5 112.5 258.9 184.4 168.7 95.5 64.3 57.9 120.2 249.7 128.6 69.8 136.8 162.3 75.5 83.1 95.9 60.2 85.9 114.5 412.0 12.7 90.7 254.2 441.0 132.7 193.3 194.5 90.1 23.9 56.1 76.8 160.7 489.5 34.7 32.6 53.4 75.8 231.2 45.4 39.9 111.4 93.2 229.1 52.3 84.8 163.5 177.9 225.8 104.1 342.2 77.6 91.8 115.4 127.1 158.0 82.1 124.3 78.3 44.6 147.4 79.0 67.6 1.8 32.0 9.7 2.5 36.4 3.5 8.3 2.5 2.9 13.3 7.1 4.5 4.1 18.6 3.3 36.1 22.9 2.3 16.0 154.1 147.4 143.9 226.4 158.9 149.8 151.6 155.6 160.5 152.1 163.1 140.2 54.5 19.2 52.7 35.3 45.4 37.2 32.5 58.7 121.3 91.1 62.7 79.4 23.2 45.8 27.9 53.3 79.2 137.2 22.6 29.1 23.5 75.0 273.8 36.8 56.1 47.7 42.1 60.0 21.3 69.1 55.8 67.7 16.8 36.1 16.4 76.2 51.4 194.5 178.4 33.7 26.6 24.3 42.7 225.1 86.7 432.6 61.5 184.3 37.4 22.5 355.1 89.9 6.2 12.5 9.3 66.0 54.5 67.7 44.4 46.7 72.9 73.6 29.4 95.8 46.0 32.4 45.6 96.0 16.9 83.2 36.9 264.2 20.8 38.7 31.4 25.5 SPATC1 "MGC61633, SPATA15, SPERIOLIN" ENSG00000186583 "Spermatogenesis and centriole associated 1" Q76KD6 8 144012280-144047114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 37.5" "Cell type enriched" "Detected in some" 4 "Late spermatids: 358.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "cerebellum: 1.2;medulla oblongata: 1.9;pons: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "U-937: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 13.9" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "unprognostic (2.96e-1)" "unprognostic (1.41e-3)" "unprognostic (3.34e-1)" "unprognostic (4.18e-2)" "unprognostic (1.65e-1)" "unprognostic (4.59e-3)" "unprognostic (6.96e-2)" "unprognostic (4.30e-2)" "unprognostic (1.49e-2)" "unprognostic (2.77e-1)" "unprognostic (4.12e-2)" "unprognostic (4.39e-2)" "unprognostic (1.34e-3)" "unprognostic (2.74e-1)" "unprognostic (5.81e-3)" "unprognostic (2.19e-1)" "unprognostic (2.74e-1)" 0.2 0.1 0.2 1.8 0.2 8.4 0.1 1.2 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.2 0.0 0.3 0.3 0.8 0.6 1.9 0.2 0.0 0.1 0.0 0.0 0.2 1.7 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.1 0.0 2.0 0.2 37.5 0.3 0.1 0.0 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.2 1.2 0.4 0.2 0.0 1.9 0.2 1.7 0.0 0.3 0.2 0.0 0.0 0.5 5.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.3 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 358.1 2.5 0.5 0.0 0.0 4.3 0.0 0.0 1.0 0.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OPLAH "5-Opase, OPLA" ENSG00000178814 "5-oxoprolinase, ATP-hydrolysing" O14841 8 144051266-144063965 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 66.5" "Group enriched" "Detected in many" 4 "Early spermatids: 115.7;Late spermatids: 231.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.1" "Group enriched" "Detected in many" 9 "granulocytes: 1.1;monocytes: 1.1" "Cell line enhanced" "Detected in many" "AN3-CA: 33.9;BEWO: 21.0;Hep G2: 18.8;PC-3: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026562, HPA028260, HPA052429" Uncertain Approved "Nucleoli fibrillar center" NA NA 34000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "HPA026562: AB_1854804, HPA028260: AB_10601383, HPA052429: AB_2681830" "unprognostic (7.89e-2)" "unprognostic (3.08e-2)" "unprognostic (1.69e-1)" "unprognostic (9.09e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-3)" "unprognostic (2.04e-2)" "unprognostic (9.37e-2)" "unprognostic (2.90e-1)" "unprognostic (1.26e-1)" "unprognostic (6.82e-2)" "unprognostic (3.62e-1)" "prognostic favorable (1.53e-6)" "unprognostic (4.03e-3)" "unprognostic (4.33e-1)" "unprognostic (3.54e-2)" "unprognostic (8.24e-2)" 9.2 14.8 3.3 1.9 5.6 2.7 8.6 8.1 3.7 6.4 5.7 15.0 13.8 4.8 0.6 15.6 4.2 2.5 35.1 2.9 2.7 15.8 34.3 6.4 0.8 12.2 5.6 5.7 10.0 6.7 3.2 1.3 12.5 8.9 2.2 0.3 11.2 5.7 34.2 13.3 12.2 1.1 3.9 9.1 19.7 66.5 5.3 0.3 5.9 15.4 0.5 4.8 9.5 6.5 4.2 4.2 0.4 33.9 1.5 3.1 21.0 2.1 1.3 1.2 0.7 8.1 7.8 0.0 6.8 3.8 0.0 5.5 1.0 3.1 0.1 1.1 0.0 1.4 7.0 18.8 10.5 0.1 0.0 4.4 13.8 1.4 0.0 0.0 0.2 5.8 5.1 0.0 0.0 4.8 0.3 3.3 2.8 6.5 26.2 0.4 0.0 5.6 3.6 5.1 1.2 0.1 0.0 1.4 0.1 0.4 8.8 4.6 0.2 0.0 5.5 0.0 1.4 1.1 1.5 1.1 0.5 1.1 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.4 3.3 5.6 8.1 3.7 2.9 2.7 12.2 5.6 12.5 3.9 5.3 6.5 1.1 3.2 3.2 9.1 0.8 2.0 2.8 4.4 3.4 1.1 6.1 6.1 2.9 7.2 4.7 9.2 0.0 1.7 0.2 37.6 11.7 3.8 115.7 2.6 2.7 1.1 1.2 0.0 0.2 2.7 2.7 2.7 18.3 5.5 0.0 6.0 2.2 25.1 2.4 0.0 0.3 10.0 4.1 6.0 0.5 231.7 2.5 3.4 0.0 1.0 2.1 4.3 0.0 0.5 2.6 3.6 13.1 3.8 0.6 1.9 23.8 13.3 2.2 0.1 0.0 3.6 2.2 3.1 2.3 7.2 1.8 2.5 0.6 10.2 18.2 3.0 EXOSC4 "FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p" ENSG00000178896 "Exosome component 4" Q9NPD3 8 144078648-144080648 "Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.9" "Group enriched" "Detected in many" 4 "Early spermatids: 320.6;Late spermatids: 856.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 430.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024792, HPA065103" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA024792: AB_1848325, HPA065103: " "unprognostic (2.32e-1)" "unprognostic (1.55e-2)" "unprognostic (3.06e-1)" "unprognostic (3.53e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.58e-3)" "unprognostic (1.26e-1)" "unprognostic (8.36e-2)" "prognostic favorable (2.23e-4)" "unprognostic (4.32e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "unprognostic (5.18e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.11e-2)" 19.3 31.2 15.1 11.4 16.5 14.9 16.9 16.0 23.4 13.1 16.1 18.8 15.4 17.0 5.0 27.5 16.1 7.2 23.7 15.6 15.0 23.6 35.0 16.0 12.1 16.8 14.9 12.3 18.8 10.3 17.6 9.2 15.5 18.8 5.7 3.5 26.6 12.5 21.2 22.1 15.2 6.1 15.4 23.8 24.0 94.9 15.8 10.1 13.9 8.2 6.6 17.4 15.2 15.9 51.8 104.8 18.1 44.2 15.6 11.7 51.8 39.9 15.2 28.9 28.9 73.4 33.4 28.9 54.6 15.5 21.0 40.4 33.8 40.5 8.3 42.5 117.8 42.7 77.9 83.3 25.9 31.4 48.6 16.9 40.9 33.2 26.2 11.4 14.8 32.0 68.8 19.8 23.8 177.8 51.4 62.0 47.6 51.2 430.6 21.7 30.2 74.8 27.7 48.3 57.6 75.4 46.6 59.7 95.4 9.3 68.1 49.0 15.2 29.9 66.3 73.6 68.1 52.4 67.8 37.5 43.1 50.8 47.7 61.5 78.3 34.1 37.4 76.6 38.7 59.7 29.3 37.4 75.0 60.2 37.7 36.2 22.9 45.6 43.0 97.4 36.1 49.5 15.1 16.5 16.0 23.4 15.6 15.0 16.8 14.9 15.5 15.4 15.8 15.9 16.3 9.6 21.3 2.9 17.8 94.4 45.2 58.6 45.5 10.0 40.7 41.4 22.3 24.3 31.9 27.6 8.4 48.2 17.2 46.6 123.3 50.6 320.6 23.8 28.3 25.5 25.9 24.6 3.2 46.3 44.2 24.7 25.0 18.8 14.0 21.0 19.2 54.9 44.7 6.7 3.3 35.6 48.8 29.8 40.7 856.7 18.6 29.9 35.6 0.0 45.7 23.5 14.4 3.0 3.6 61.7 52.4 21.1 32.5 55.5 41.0 102.5 31.7 8.2 13.1 14.7 43.5 97.0 34.7 48.1 87.9 48.2 12.8 37.8 47.1 48.7 GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082590-144086216 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 275.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (2.53e-3)" "unprognostic (1.39e-1)" "unprognostic (3.06e-2)" "unprognostic (2.57e-2)" "unprognostic (2.49e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-3)" "unprognostic (2.64e-1)" "unprognostic (8.92e-2)" "unprognostic (1.67e-2)" "unprognostic (2.04e-3)" "unprognostic (4.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" 47.0 75.5 35.7 21.2 37.5 48.2 46.7 39.9 43.6 52.2 62.3 46.1 35.8 56.9 18.8 51.7 45.9 25.0 72.1 35.9 35.6 61.9 69.9 42.6 23.4 41.9 37.4 49.9 66.2 47.5 37.2 20.0 40.7 50.9 13.1 11.4 60.5 40.5 71.7 47.1 46.8 18.8 40.1 48.4 55.8 40.9 38.1 18.6 60.1 28.4 12.9 43.0 42.8 47.6 67.3 117.2 26.9 84.7 60.8 51.5 92.8 68.5 66.5 55.8 57.4 49.0 108.9 36.6 94.1 73.9 26.4 82.5 17.9 67.2 8.1 60.4 59.0 58.0 53.1 36.3 58.6 28.5 83.2 56.8 61.6 56.9 39.4 45.0 46.4 61.5 42.1 125.7 54.1 237.6 55.9 26.5 27.2 79.3 275.8 38.1 34.2 176.9 48.4 46.8 45.7 63.2 88.8 112.4 51.1 14.7 73.2 79.3 31.6 51.8 88.6 29.5 77.2 70.0 57.5 24.9 91.2 34.8 72.0 35.7 64.4 59.0 84.2 78.1 57.2 37.4 41.7 66.7 59.6 40.1 40.6 57.7 14.8 69.1 91.9 107.1 40.1 76.7 35.7 37.5 39.9 43.6 35.9 35.6 41.9 37.4 40.7 40.1 38.1 47.6 41.0 38.5 40.0 13.7 46.7 28.8 54.9 84.6 37.0 60.8 74.9 59.9 42.7 55.8 58.0 44.1 64.6 123.4 72.5 100.2 25.4 125.8 5.7 30.8 30.7 37.3 56.9 48.0 12.8 89.9 152.9 57.1 56.6 37.3 64.8 45.1 42.5 74.9 86.6 55.5 14.6 52.6 79.3 53.6 25.6 10.9 40.4 41.2 72.9 6.5 57.4 98.0 98.9 15.6 20.4 76.0 91.0 37.6 85.5 58.0 155.1 90.3 46.8 73.2 59.2 50.8 50.5 194.8 109.9 55.9 22.3 109.3 38.9 66.5 85.3 48.1 CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 730.0;tongue: 724.9" "Cell type enhanced" "Detected in all" "Distal tubular cells: 817.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 1125.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001247 Supported Approved Mitochondria NA NA 45000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "HPA001247: AB_1078602" "unprognostic (3.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-1)" "unprognostic (6.52e-2)" "unprognostic (1.39e-1)" "unprognostic (3.92e-3)" "unprognostic (6.23e-2)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (2.15e-1)" "prognostic favorable (5.89e-6)" "unprognostic (6.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-1)" "unprognostic (3.13e-2)" 84.7 173.2 92.1 62.4 97.2 104.4 72.7 115.4 103.8 71.4 102.4 162.6 171.2 75.9 35.7 155.5 67.8 39.5 527.7 92.3 105.3 152.6 180.4 56.7 55.8 99.8 96.9 63.6 101.2 163.3 58.2 45.8 103.1 67.8 111.0 42.0 104.4 70.0 730.0 106.5 127.5 59.9 94.9 70.1 139.6 38.9 106.9 63.4 64.8 724.9 61.0 92.0 86.5 99.6 172.0 381.4 98.9 208.4 80.5 88.5 189.6 96.7 116.7 240.2 156.9 269.4 208.2 241.0 210.8 129.8 116.2 247.3 217.9 191.2 89.8 148.2 289.2 259.7 306.5 250.4 143.1 154.7 162.5 129.4 234.9 153.2 301.4 80.6 141.3 163.7 240.4 208.2 127.7 616.8 292.0 143.5 115.1 476.8 1125.5 253.7 132.4 422.1 199.7 273.0 263.3 117.2 267.8 365.7 200.0 54.0 302.5 233.2 108.8 152.1 321.6 169.6 299.7 229.1 179.7 183.8 193.2 261.9 198.4 185.7 340.4 95.7 131.6 360.4 139.8 208.7 108.1 141.5 444.1 180.3 104.9 134.6 32.7 187.8 278.8 251.0 158.2 397.1 92.1 97.2 115.4 103.8 92.3 105.3 99.8 96.9 103.1 94.9 106.9 99.6 77.0 19.2 29.3 23.5 94.0 156.1 191.9 394.8 62.6 113.6 110.7 102.6 402.3 181.6 156.0 79.1 81.3 263.6 61.7 516.1 817.8 239.9 81.2 59.1 68.1 88.0 146.4 130.6 14.4 289.1 257.1 102.8 144.8 60.2 59.7 89.2 62.4 239.4 246.3 87.5 21.6 390.4 272.6 104.8 139.4 88.6 88.9 101.4 179.7 12.2 208.4 115.2 92.7 12.1 17.5 290.6 332.5 90.7 149.9 237.9 570.0 468.6 86.1 100.9 72.3 109.4 250.6 83.1 116.7 212.9 163.7 236.8 63.8 197.5 602.6 258.3 SHARPIN "DKFZP434N1923, SIPL1" ENSG00000179526 "SHANK associated RH domain interactor" Q9H0F6 8 144098633-144108124 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 391.4;Late spermatids: 1255.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024825, HPA044453" Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA024825: , HPA044453: AB_10962490" "unprognostic (4.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.35e-2)" "unprognostic (7.88e-2)" "unprognostic (3.32e-2)" "unprognostic (9.54e-2)" "unprognostic (1.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.13e-3)" "unprognostic (5.44e-2)" "unprognostic (7.91e-2)" "unprognostic (1.84e-3)" "unprognostic (2.87e-2)" "unprognostic (1.55e-1)" "unprognostic (2.24e-1)" "unprognostic (1.00e-1)" 29.9 39.2 38.5 16.5 39.9 32.6 27.2 39.1 52.2 29.9 35.7 37.7 20.7 29.4 11.2 29.9 28.8 19.4 44.4 36.0 39.2 36.7 39.1 27.1 21.8 41.7 39.7 27.4 35.1 28.7 26.7 17.2 39.9 33.8 12.7 8.9 33.8 22.2 49.4 27.1 26.3 17.3 37.7 33.4 34.2 94.7 39.8 19.6 29.1 39.7 13.9 31.2 26.4 38.7 26.9 43.5 20.4 17.9 34.2 35.1 22.5 23.5 29.5 34.0 32.9 24.9 42.0 12.0 38.5 30.6 17.1 28.4 10.8 42.2 8.2 33.0 23.3 31.4 40.1 29.9 61.6 11.6 23.1 40.4 59.4 28.3 30.8 37.6 36.8 36.6 18.2 27.3 30.2 43.8 35.2 26.6 9.3 53.6 124.2 23.6 16.7 39.4 35.2 28.3 20.3 30.7 45.0 62.1 41.5 14.3 69.4 35.8 34.0 26.5 38.9 32.5 32.4 30.0 25.4 16.3 38.3 25.9 23.5 22.6 33.5 53.5 29.9 41.2 32.4 23.3 28.5 38.3 30.0 21.8 23.5 24.7 17.5 33.9 34.8 42.7 34.1 22.4 38.5 39.9 39.1 52.2 36.0 39.2 41.7 39.7 39.9 37.7 39.8 38.7 56.3 9.6 18.1 10.4 39.4 24.0 32.9 37.0 26.2 27.1 43.5 44.4 20.9 31.5 26.1 35.0 4.2 56.7 44.4 87.2 119.3 53.8 391.4 28.3 26.8 38.9 35.4 88.0 8.0 49.5 52.6 35.9 52.0 24.4 13.3 35.1 36.4 37.2 59.0 48.8 9.5 45.6 44.7 42.1 32.9 1255.3 49.0 33.0 46.2 15.0 57.7 45.4 59.8 9.0 14.3 95.2 81.3 43.6 31.2 36.1 83.1 86.4 20.6 28.9 52.6 26.8 44.2 181.7 67.9 33.5 32.4 43.1 38.8 37.4 59.0 33.9 MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024821, HPA058548" Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nucleoli, Vesicles" "HPA024821: AB_2671696, HPA058548: AB_2683751" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.71e-2)" "unprognostic (2.21e-1)" "unprognostic (8.51e-2)" "unprognostic (9.67e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.12e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (9.40e-3)" "unprognostic (9.02e-2)" "unprognostic (2.59e-1)" "unprognostic (2.38e-1)" "unprognostic (3.99e-2)" 96.2 84.4 86.6 61.7 89.7 164.4 92.4 87.3 98.3 97.1 82.5 186.9 62.1 101.9 63.6 81.8 93.3 63.0 193.4 83.5 82.7 89.8 61.1 78.0 78.6 91.2 87.6 110.3 84.6 87.4 71.0 65.1 86.4 103.6 58.3 35.4 77.5 94.6 413.1 69.6 92.2 80.5 85.3 96.5 102.1 76.4 88.7 90.8 78.6 294.7 69.5 130.7 84.1 90.5 119.8 187.1 85.4 86.3 229.0 113.3 68.9 91.8 151.0 140.5 142.1 69.2 129.1 131.0 150.4 154.9 78.1 71.4 117.4 129.9 103.0 115.4 139.5 144.5 127.8 109.6 154.1 62.0 94.4 100.7 150.0 112.8 211.4 156.7 153.6 94.1 112.5 86.9 85.0 281.2 230.9 112.3 64.0 216.3 490.2 90.3 119.7 141.8 89.0 88.8 123.8 102.2 122.0 156.7 152.6 79.5 106.7 93.9 93.0 65.0 146.0 116.1 117.5 102.7 86.0 62.2 107.8 113.7 44.0 50.4 98.0 126.5 72.8 76.1 81.0 110.2 105.0 117.5 107.6 129.9 110.9 105.0 52.9 93.1 78.4 81.0 84.1 111.9 86.6 89.7 87.3 98.3 83.5 82.7 91.2 87.6 86.4 85.3 88.7 90.5 76.8 16.0 15.6 6.8 95.2 92.9 92.4 51.6 53.5 41.4 76.5 77.8 54.2 42.9 24.8 44.1 14.6 106.4 113.9 82.6 105.7 101.1 86.1 30.0 39.3 69.7 93.3 129.0 5.0 107.9 103.6 66.3 28.5 43.6 32.5 77.3 67.5 29.3 97.6 37.0 5.5 89.7 32.6 72.3 85.6 41.0 88.3 84.9 78.2 6.5 138.0 82.0 138.0 7.1 10.7 106.0 97.4 93.3 60.3 170.3 155.0 110.2 12.9 37.6 98.6 65.5 84.8 96.1 43.3 54.0 89.8 144.3 87.6 72.4 88.5 122.4 WDR97 KIAA1875 ENSG00000179698 "WD repeat domain 97" A6NE52 8 144107726-144118328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "testis: 1.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.0;Cone photoreceptor cells: 6.2;Gastric mucus-secreting cells: 5.1;Horizontal cells: 5.0;Rod photoreceptor cells: 8.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059409 Uncertain NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: Photoreceptor cells - Phototransduction" "HPA059409: AB_2684005" "unprognostic (3.95e-2)" "unprognostic (1.31e-2)" "unprognostic (3.58e-3)" "unprognostic (1.70e-1)" "unprognostic (2.70e-1)" "unprognostic (3.01e-4)" "unprognostic (3.10e-2)" "unprognostic (2.40e-1)" "unprognostic (6.20e-2)" "unprognostic (1.40e-1)" "unprognostic (2.97e-3)" "unprognostic (6.92e-2)" "unprognostic (6.11e-6)" "unprognostic (2.79e-3)" "unprognostic (4.95e-2)" "unprognostic (2.51e-1)" "unprognostic (3.73e-4)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.3 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.2 0.8 0.0 1.7 0.0 0.9 0.0 0.2 0.0 0.6 7.0 1.3 1.3 0.0 1.5 0.0 0.0 6.2 0.1 3.1 0.3 1.9 0.7 4.4 2.2 0.4 0.4 0.0 0.4 0.0 0.2 0.0 0.4 5.1 0.7 0.0 0.8 0.7 1.7 0.2 5.0 0.0 0.4 0.0 0.0 0.0 2.7 0.0 0.6 0.0 0.0 0.3 3.9 0.0 0.0 0.0 0.6 2.6 0.0 0.5 0.6 1.5 0.2 0.7 8.5 0.0 2.1 0.6 3.8 2.2 0.8 0.0 0.0 0.6 0.0 0.7 0.3 HGH1 "Brp16, C8orf30A, C8orf30B, FAM203A, FAM203B, FLJ40907, LOC51236" ENSG00000235173 "HGH1 homolog" Q9BTY7 8 144137774-144140851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 26.4;PC-3: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042470 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear bodies, Cytosol" Nucleoplasm "HPA042470: AB_2678013" "unprognostic (2.13e-2)" "prognostic unfavorable (3.12e-4)" "unprognostic (9.72e-2)" "unprognostic (2.63e-1)" "unprognostic (9.82e-2)" "unprognostic (2.17e-1)" "unprognostic (7.89e-3)" "unprognostic (1.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.30e-2)" "unprognostic (4.39e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.72e-5)" "unprognostic (4.62e-3)" "unprognostic (3.10e-1)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" 2.3 3.2 1.8 1.0 1.3 0.6 1.5 1.4 1.8 2.0 1.2 1.9 0.6 2.3 0.1 3.1 1.7 0.5 2.1 1.7 1.1 1.9 3.2 1.3 0.6 2.1 1.2 1.7 3.1 0.8 1.4 0.4 1.4 1.9 0.5 0.1 1.8 0.8 2.7 2.2 1.6 0.7 1.3 2.2 2.9 2.4 1.5 0.6 2.0 1.2 0.6 2.6 1.9 1.6 8.3 2.7 1.9 3.5 2.7 1.7 4.9 13.8 1.1 2.9 1.9 3.6 2.1 23.9 18.7 2.6 1.1 8.6 3.8 1.9 0.9 11.7 14.5 9.1 2.4 1.8 2.6 5.1 5.9 1.2 5.9 3.2 2.0 1.0 1.3 4.9 26.4 0.9 1.8 6.9 17.5 4.7 5.4 3.1 46.6 21.8 1.6 3.7 1.7 1.9 4.1 4.4 6.4 3.4 5.1 0.6 2.9 1.8 4.9 1.7 14.2 5.1 16.5 13.9 9.7 6.1 1.7 8.5 2.8 0.0 0.1 0.0 0.3 0.2 0.2 0.1 0.4 0.7 0.2 0.8 0.4 0.3 0.0 0.6 0.2 0.1 0.1 0.1 1.8 1.3 1.4 1.8 1.7 1.1 2.1 1.2 1.4 1.3 1.5 1.6 5.2 0.0 2.4 2.6 5.8 0.0 2.6 0.0 5.2 4.2 6.7 5.7 2.2 2.8 0.6 5.5 0.0 11.1 7.2 1.3 11.7 3.5 11.2 2.8 7.0 3.1 4.9 5.9 1.2 1.8 13.4 4.3 7.1 4.0 0.0 7.9 1.4 9.9 12.2 6.7 1.2 4.0 0.0 4.8 0.0 22.1 7.5 5.6 0.0 1.0 3.5 8.3 14.4 0.0 1.0 2.9 5.6 3.4 4.9 3.2 5.4 10.2 1.5 3.7 6.6 2.6 3.8 15.1 14.8 6.9 0.0 3.1 5.9 11.0 6.5 1.6 MROH1 "HEATR7A, KIAA1833" ENSG00000179832 "Maestro heat like repeat family member 1" Q8NDA8 8 144148016-144261940 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 58.8" "Cell type enhanced" "Detected in all" "Gastric mucus-secreting cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024287, HPA044465" Approved Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Cytosol "HPA024287: , HPA044465: AB_10960985" "unprognostic (1.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "prognostic favorable (6.74e-4)" "unprognostic (2.97e-2)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (4.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.48e-2)" "unprognostic (6.64e-2)" "unprognostic (1.92e-1)" "prognostic favorable (3.65e-6)" "unprognostic (1.61e-3)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-2)" 9.2 17.0 7.3 6.3 6.9 18.0 11.0 5.4 15.5 10.5 6.4 16.2 13.3 9.1 5.3 17.0 11.0 3.6 14.0 7.5 2.7 17.2 11.7 17.0 7.0 11.8 4.2 7.7 26.7 5.6 22.3 5.5 10.9 17.2 3.4 0.9 17.3 5.7 5.2 17.8 17.6 2.1 1.1 21.7 18.9 13.0 4.9 4.2 58.8 2.1 3.7 12.9 12.6 3.8 17.0 6.9 0.9 6.5 3.1 3.3 29.3 7.3 5.1 4.0 5.5 11.6 29.7 8.9 10.5 4.2 9.8 15.9 1.0 11.2 1.8 5.1 9.5 10.8 22.1 10.7 7.8 4.8 11.0 6.1 11.4 6.4 9.2 4.7 5.8 7.2 4.5 3.9 4.5 36.3 8.4 10.2 2.5 11.6 32.0 10.8 2.2 9.3 5.9 33.0 7.4 6.4 18.3 17.5 5.4 2.5 12.8 6.7 14.6 8.1 15.2 16.6 6.1 6.8 3.6 9.5 16.0 14.3 4.9 4.8 5.7 1.5 1.8 7.5 1.3 0.9 1.5 1.8 4.3 1.5 1.4 1.0 1.1 0.8 6.8 1.3 4.6 2.2 7.3 6.9 5.4 15.5 7.5 2.7 11.8 4.2 10.9 1.1 4.9 3.8 5.2 9.6 26.3 33.0 6.5 6.2 8.5 9.2 6.8 36.4 12.6 9.5 12.4 5.7 16.6 5.5 12.5 31.3 7.0 39.8 3.9 12.2 5.1 17.8 6.7 7.8 23.4 1.7 56.7 16.6 19.2 6.4 63.7 25.2 14.5 14.3 3.9 7.0 19.7 37.0 61.2 24.8 18.3 11.9 11.4 12.2 3.1 14.5 1.8 13.1 11.4 5.7 7.2 14.6 7.9 18.6 17.5 2.6 9.7 17.6 30.7 5.8 18.8 3.5 6.6 7.2 6.7 19.1 26.2 9.7 5.8 50.1 9.1 7.8 22.3 14.8 BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 76.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 223.5" "Low region specificity" "Detected in all" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: AB_2680193, HPA066764: AB_2685716" "unprognostic (6.92e-2)" "unprognostic (5.03e-3)" "unprognostic (6.78e-2)" "unprognostic (2.06e-3)" "unprognostic (3.32e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (3.35e-5)" "unprognostic (2.25e-2)" "unprognostic (4.14e-1)" "unprognostic (3.31e-1)" "unprognostic (2.26e-2)" "unprognostic (7.00e-2)" "prognostic unfavorable (2.23e-7)" "unprognostic (7.83e-2)" "unprognostic (4.33e-1)" "unprognostic (8.49e-2)" "unprognostic (4.06e-3)" 18.1 17.8 6.8 8.8 6.9 9.7 16.3 7.7 10.9 16.1 3.5 17.3 5.6 18.2 1.0 26.0 13.2 2.8 24.4 7.6 5.5 16.7 21.5 13.3 8.0 7.1 6.0 11.1 32.0 5.6 16.9 3.7 6.5 15.3 1.9 1.1 13.2 3.1 76.6 21.4 14.9 3.1 4.7 20.4 15.4 20.1 6.2 5.4 17.0 8.1 3.6 19.3 16.5 6.1 45.0 87.4 11.8 50.6 6.4 7.7 41.4 30.5 6.5 30.3 19.1 66.3 25.4 54.1 50.1 11.6 11.5 34.9 21.2 36.2 6.9 47.8 82.5 68.4 54.4 49.7 15.1 30.8 35.6 15.5 17.0 25.2 22.1 5.7 18.8 48.3 70.1 18.1 11.9 112.8 82.4 37.6 28.3 45.1 223.5 61.4 17.6 82.2 12.5 30.1 64.7 25.8 32.5 41.9 20.3 5.5 30.6 27.7 36.6 27.8 83.3 37.1 88.5 16.5 11.7 45.6 20.3 48.6 36.7 0.0 2.2 1.3 1.9 2.3 2.1 2.5 2.2 2.5 3.0 1.8 2.0 1.8 0.1 1.8 2.0 2.0 2.0 1.2 6.8 6.9 7.7 10.9 7.6 5.5 7.1 6.0 6.5 4.7 6.2 6.1 12.8 9.6 5.1 3.9 16.7 0.5 18.7 0.0 13.1 9.8 12.7 13.8 7.2 10.0 3.7 11.0 0.0 25.2 20.9 18.7 5.9 25.8 11.2 7.5 10.7 12.0 26.9 22.1 4.4 21.7 45.3 13.2 17.3 8.3 10.2 13.5 4.6 14.8 21.5 15.2 3.5 11.5 0.0 11.1 0.0 24.3 10.5 12.8 0.0 1.0 16.2 16.7 18.6 5.0 2.8 26.4 11.3 9.8 25.4 39.5 11.3 17.2 1.5 4.6 13.1 12.9 15.1 13.9 53.4 25.7 0.1 17.8 11.8 29.6 31.8 14.3 SCX "bHLHa41, bHLHa48, SCXA, SCXB" ENSG00000260428 "Scleraxis bHLH transcription factor" Q7RTU7 8 144266453-144268481 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 38.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.2;Horizontal cells: 16.8" "Group enriched" "Detected in all" 6 "endometrial cancer: 12.8;ovarian cancer: 34.4;thyroid cancer: 37.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.8;HaCaT: 5.3" "Region enhanced" "Detected in many" "cerebellum: 10.7" "Low region specificity" "Detected in some" HPA043183 Uncertain NA NA "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "HPA043183: AB_2678357" "unprognostic (5.32e-2)" "unprognostic (1.06e-2)" "unprognostic (7.37e-3)" "unprognostic (1.87e-3)" "prognostic unfavorable (2.86e-4)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.03e-2)" "unprognostic (2.27e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-2)" "unprognostic (6.86e-2)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (7.89e-3)" 1.4 3.4 3.0 0.9 2.3 0.6 1.4 7.8 7.0 7.8 2.9 8.3 0.9 2.9 0.5 3.4 3.8 0.1 11.0 2.7 2.9 8.4 2.1 3.5 0.4 6.2 1.9 2.5 3.8 0.8 19.6 0.2 5.4 4.5 0.2 0.1 2.7 0.1 13.8 3.2 5.0 0.2 0.9 4.6 5.9 5.2 2.3 0.7 38.1 1.2 0.1 2.6 3.2 1.8 2.0 0.4 0.1 0.5 0.0 0.0 4.8 0.1 0.0 0.1 0.0 0.1 1.4 1.3 1.4 0.2 0.2 5.3 0.0 0.0 0.0 0.9 0.8 0.3 1.9 0.2 0.2 0.1 2.2 0.0 0.5 0.0 0.2 0.7 0.0 0.3 0.2 0.6 0.1 3.0 0.5 1.1 1.1 0.4 2.3 1.6 0.2 0.8 0.1 2.0 0.2 0.9 0.5 1.8 2.2 0.1 2.3 0.9 0.3 0.4 3.5 1.6 0.3 1.8 0.6 0.3 0.8 1.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 2.3 7.8 7.0 2.7 2.9 6.2 1.9 5.4 0.9 2.3 1.8 3.4 0.0 2.7 8.5 2.5 0.0 1.2 0.0 0.6 14.2 6.7 8.3 6.2 1.5 1.3 3.7 0.0 1.5 7.5 2.2 1.9 0.6 0.2 5.7 1.4 1.2 2.4 0.0 5.9 1.4 0.6 1.2 8.2 7.1 0.0 3.2 0.4 0.4 0.4 16.8 8.5 2.3 0.0 0.6 0.0 0.9 0.3 0.9 0.0 1.0 0.0 8.2 1.0 2.5 0.3 1.5 2.1 0.7 0.7 2.7 1.5 0.2 0.0 1.5 0.0 4.2 6.4 2.5 9.0 0.6 0.0 1.1 3.1 0.3 1.8 1.0 HSF1 HSTF1 ENSG00000185122 "Heat shock transcription factor 1" Q00613 8 144291591-144314720 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Host-virus interaction, mRNA processing, mRNA transport, Stress response, Transcription, Transcription regulation, Transport" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 248.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004239, HPA008888" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Cytosol "CAB004239: AB_627753, HPA008888: AB_1079088" "unprognostic (7.08e-2)" "unprognostic (1.89e-2)" "unprognostic (6.07e-2)" "prognostic unfavorable (8.93e-4)" "unprognostic (1.55e-1)" "unprognostic (5.63e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (5.69e-3)" "unprognostic (1.05e-1)" "unprognostic (4.35e-2)" "unprognostic (1.40e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.07e-2)" "unprognostic (2.23e-1)" "unprognostic (2.13e-1)" "unprognostic (1.12e-1)" 51.7 55.7 20.0 14.7 19.2 18.0 47.9 18.2 24.0 48.6 17.0 70.6 14.1 51.7 7.4 48.1 52.1 12.4 133.5 18.6 19.1 50.2 46.0 49.5 14.5 22.3 21.4 57.3 68.7 18.7 48.1 17.0 20.2 53.2 10.8 7.6 39.8 17.1 125.1 49.2 39.7 15.3 18.6 42.8 57.8 107.8 21.7 14.7 45.7 32.2 12.6 58.7 46.2 18.0 40.8 53.8 22.9 19.6 37.6 35.0 37.9 29.7 26.6 28.8 25.0 36.3 34.6 46.7 42.5 41.5 28.2 28.9 35.2 42.7 18.3 29.9 40.7 58.4 51.8 50.1 59.1 17.1 43.4 34.2 39.3 40.6 74.2 30.6 39.4 41.9 39.6 27.1 29.4 82.0 58.0 26.2 29.4 52.6 154.2 37.2 19.9 59.2 20.6 40.5 34.3 27.9 45.4 35.9 52.8 23.8 40.5 34.5 40.2 29.5 66.3 46.8 49.5 18.8 15.4 39.9 41.8 31.4 28.8 14.2 23.2 26.3 16.7 24.9 17.2 19.2 17.8 21.1 24.6 17.3 17.1 15.9 9.7 16.3 32.2 12.6 22.9 19.2 20.0 19.2 18.2 24.0 18.6 19.1 22.3 21.4 20.2 18.6 21.7 18.0 46.5 6.4 11.2 8.5 40.4 51.4 73.8 53.8 39.9 67.8 37.0 30.5 46.4 22.8 34.7 29.5 62.6 69.9 38.2 43.3 150.6 39.2 248.7 35.1 20.5 44.4 40.9 120.8 12.1 41.1 80.6 34.7 44.9 34.6 37.5 51.1 40.7 63.8 49.5 69.0 14.7 36.8 42.7 25.7 45.6 106.7 37.3 32.7 33.8 12.2 59.7 24.9 34.0 6.0 12.9 45.3 49.3 42.9 40.4 76.6 63.8 34.9 25.9 33.1 59.2 41.3 39.2 84.4 47.7 36.3 45.5 111.0 39.0 105.9 45.8 76.4 DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 40.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 213.5;Proximal enterocytes: 700.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 18.4;PC-3: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: AB_2090798" "unprognostic (9.24e-3)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.23e-1)" "unprognostic (3.49e-2)" "unprognostic (2.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (5.10e-2)" "unprognostic (2.78e-2)" "unprognostic (6.88e-2)" "unprognostic (3.52e-1)" "unprognostic (2.65e-3)" "unprognostic (3.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.67e-3)" 15.0 24.7 4.6 1.8 4.6 5.1 11.8 5.5 5.6 6.1 4.1 16.7 37.0 5.6 1.0 8.6 5.1 2.0 11.7 4.7 4.1 7.9 16.5 6.9 1.8 4.5 4.6 4.3 6.5 3.9 6.5 1.5 4.2 6.6 4.2 1.6 7.4 2.4 11.7 6.9 40.6 1.6 4.1 9.3 8.7 14.7 4.4 2.3 7.4 3.5 1.4 6.7 6.4 4.5 5.2 4.9 2.2 4.1 3.5 1.5 2.9 3.4 3.1 2.9 2.0 11.2 3.1 2.1 12.4 1.9 1.6 4.0 1.8 4.3 0.6 3.7 5.1 3.3 4.2 18.4 2.5 1.0 3.4 2.1 3.2 2.0 2.1 2.1 2.3 7.3 2.9 5.2 1.9 3.7 6.8 4.1 1.1 10.9 21.2 7.7 0.9 3.4 2.8 2.5 2.6 4.2 4.7 5.2 2.3 0.8 2.9 3.3 2.0 1.6 5.6 3.6 2.8 2.3 0.6 0.8 1.8 6.3 3.2 0.0 0.4 0.7 0.2 0.3 0.4 0.1 0.2 0.2 0.5 0.1 0.1 0.0 0.5 0.0 0.4 0.2 0.1 0.2 4.6 4.6 5.5 5.6 4.7 4.1 4.5 4.6 4.2 4.1 4.4 4.5 34.0 16.0 19.0 15.7 8.5 8.0 12.5 6.3 4.0 24.6 21.6 16.0 20.8 12.8 8.7 18.4 29.2 11.3 17.6 213.5 1.9 9.4 19.2 12.3 13.7 26.5 23.4 17.7 11.2 11.9 10.3 9.3 48.4 21.3 7.0 23.9 12.5 57.4 18.8 18.5 12.8 93.6 4.1 25.5 11.8 25.8 6.8 22.8 5.4 8.4 9.2 21.3 4.1 17.6 7.0 13.3 113.4 6.8 18.8 8.1 700.1 7.4 5.6 23.6 0.0 11.9 12.3 27.7 17.4 12.3 9.2 16.4 12.3 41.1 108.0 20.7 SCRT1 "DKFZp547F072, ZNF898" ENSG00000261678 "Scratch family transcriptional repressor 1" Q9BWW7 8 144330565-144336482 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "brain: 64.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 41.2;Early spermatids: 55.6;Excitatory neurons: 10.6;Horizontal cells: 35.3;Inhibitory neurons: 14.2;Late spermatids: 11.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045265 Uncertain Supported "Nuclear bodies" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear bodies" "HPA045265: AB_10959521" "unprognostic (7.70e-2)" "unprognostic (7.97e-2)" "unprognostic (6.96e-3)" "unprognostic (6.88e-4)" "unprognostic (2.43e-2)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (1.97e-1)" "unprognostic (8.02e-3)" "unprognostic (1.30e-1)" "unprognostic (1.83e-4)" "unprognostic (5.02e-2)" "unprognostic (7.05e-2)" "unprognostic (2.78e-1)" "unprognostic (2.35e-1)" "unprognostic (2.66e-3)" "unprognostic (1.04e-1)" 0.0 0.5 3.4 0.0 4.8 0.0 0.0 12.5 64.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 19.4 0.0 0.0 0.0 0.0 22.9 8.5 0.0 0.3 0.0 3.4 0.0 18.1 0.0 0.0 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 2.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 4.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 4.8 12.5 64.2 1.6 19.4 22.9 8.5 18.1 0.1 26.2 23.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 41.2 0.0 0.1 1.6 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 55.6 0.0 0.0 0.3 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.3 14.2 0.0 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 SLC52A2 "D15Ertd747e, FLJ11856, GPCR41, GPR172A, hRFT3, PAR1, RFVT2" ENSG00000185803 "Solute carrier family 52 member 2" Q9HAB3 8 144333957-144361286 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Host cell receptor for virus entry, Receptor" "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 149.0;PC-3: 167.6" "Low region specificity" "Detected in all" HPA063036 Approved NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA063036: AB_2684928" "unprognostic (7.80e-3)" "prognostic unfavorable (7.55e-4)" "unprognostic (2.15e-1)" "unprognostic (2.94e-1)" "unprognostic (3.09e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.04e-6)" "unprognostic (7.74e-3)" "unprognostic (9.20e-2)" "unprognostic (2.24e-2)" "unprognostic (4.85e-2)" "unprognostic (3.99e-2)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.12e-2)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.07e-1)" 29.7 31.6 13.7 5.4 13.4 5.6 27.8 15.3 18.5 21.7 14.5 35.7 9.4 23.0 8.0 33.3 17.3 3.2 26.4 13.5 14.5 29.2 16.9 24.6 5.6 15.0 14.9 15.6 41.6 5.3 24.5 7.7 14.6 22.2 5.7 1.3 29.8 6.3 13.5 30.4 29.6 4.3 14.0 34.8 31.4 31.5 15.1 4.0 21.7 2.7 4.1 24.9 21.2 14.1 38.7 65.0 7.5 17.9 19.3 12.3 37.3 28.1 18.9 26.5 24.6 57.9 42.3 16.3 42.3 27.5 20.7 42.6 18.4 25.3 9.8 18.3 34.5 26.3 31.3 50.1 51.7 9.4 29.4 14.8 34.7 27.4 24.4 19.2 15.8 16.2 40.9 23.7 18.7 149.0 15.6 38.0 17.9 51.5 167.6 29.8 8.9 44.9 30.6 34.4 25.9 29.4 31.1 44.1 35.7 9.9 27.8 18.7 20.2 20.9 46.9 48.2 37.9 9.4 13.8 12.4 37.8 26.6 25.7 0.5 4.2 9.2 5.6 5.9 3.8 3.3 3.9 5.6 4.5 9.8 3.6 2.6 1.1 5.2 7.5 7.6 5.7 1.5 13.7 13.4 15.3 18.5 13.5 14.5 15.0 14.9 14.6 14.0 15.1 14.1 31.9 6.4 8.7 5.5 24.3 31.2 27.0 41.5 12.0 11.1 30.6 17.0 3.1 12.8 34.4 12.9 2.1 85.0 36.3 81.8 0.0 62.3 3.3 11.6 16.6 24.3 17.4 7.8 3.2 66.9 92.1 22.2 42.3 21.5 10.2 16.6 18.9 5.5 52.4 11.8 3.7 56.3 36.7 13.5 27.8 5.8 12.8 21.4 30.2 2.8 40.7 14.3 19.6 7.1 2.4 85.1 46.7 19.9 43.3 54.7 52.4 14.5 11.7 10.8 19.7 12.1 31.1 34.0 40.2 20.2 36.1 52.5 24.8 23.4 65.6 36.7 TMEM249 C8orfK29 ENSG00000261587 "Transmembrane protein 249" Q2WGJ8 8 144352219-144354914 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 27.6" "Group enriched" "Detected in some" 9 "Early spermatids: 32.4;Late spermatids: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078901 Approved NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "HPA078901: " "unprognostic (2.23e-1)" "unprognostic (8.91e-3)" "unprognostic (1.72e-2)" "unprognostic (1.10e-1)" "unprognostic (4.13e-2)" "unprognostic (2.41e-1)" "unprognostic (1.03e-4)" "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.30e-1)" "unprognostic (8.44e-2)" "unprognostic (3.21e-1)" "unprognostic (1.13e-7)" "unprognostic (6.56e-3)" "unprognostic (1.62e-2)" "unprognostic (8.44e-3)" "unprognostic (3.46e-2)" 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.3 0.4 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 27.6 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.4 0.2 0.0 0.0 0.2 0.3 0.4 0.0 0.1 0.4 0.0 0.2 0.3 0.0 0.1 0.4 0.1 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.4 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.3 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 32.4 0.1 0.2 0.1 0.0 0.0 1.4 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 3.3 1.6 0.3 0.0 0.0 0.0 30.4 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.1 0.0 0.4 0.1 0.1 0.0 0.3 0.0 0.8 0.0 0.0 0.1 1.1 0.7 0.0 0.0 0.0 0.1 0.0 0.4 0.0 FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "HPA008867: AB_2668161" "unprognostic (2.97e-2)" "unprognostic (3.30e-2)" "unprognostic (1.13e-3)" "unprognostic (3.13e-1)" "unprognostic (9.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.29e-3)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (9.04e-2)" "unprognostic (9.73e-2)" "prognostic unfavorable (4.49e-10)" "unprognostic (3.93e-2)" "unprognostic (1.44e-1)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" 4.6 4.8 2.3 1.4 2.3 2.0 4.9 2.5 3.2 4.3 2.5 8.0 4.6 3.5 0.6 7.2 3.1 1.0 4.1 2.3 2.2 4.6 10.8 3.9 1.8 2.5 2.4 2.1 8.1 1.6 3.8 1.8 2.4 4.2 1.8 0.5 5.1 1.6 4.2 6.6 7.8 0.7 2.4 6.8 5.5 5.2 2.6 1.5 3.3 0.3 1.2 4.6 4.3 2.3 9.0 3.0 2.1 13.3 2.7 0.7 3.8 4.4 5.1 4.5 3.1 3.2 3.9 4.1 5.3 2.2 2.2 5.8 2.4 6.1 1.0 7.6 3.0 8.2 1.6 7.9 4.0 2.1 8.4 1.2 5.5 2.5 6.6 1.2 3.7 6.7 3.8 6.6 1.7 16.7 6.0 1.9 2.6 9.8 8.3 6.7 2.4 14.0 6.0 3.0 3.1 3.0 5.1 8.0 7.7 1.2 13.2 3.7 3.3 2.2 8.1 10.8 5.4 2.5 2.1 3.0 3.4 5.1 2.9 0.0 0.1 0.6 0.4 0.4 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.3 1.6 0.7 0.0 0.0 2.3 2.3 2.5 3.2 2.3 2.2 2.5 2.4 2.4 2.4 2.6 2.3 17.9 6.4 2.0 4.6 10.1 5.7 6.0 2.1 7.4 9.9 13.2 12.8 1.1 7.2 4.6 0.0 14.6 8.3 17.3 18.2 5.9 5.2 1.9 5.2 6.8 5.9 2.4 3.0 7.4 6.2 11.6 5.2 13.7 7.8 1.3 7.7 6.8 6.7 6.9 1.7 5.6 19.4 2.0 4.7 7.6 1.6 5.3 9.0 5.4 4.7 2.6 7.9 6.2 2.0 2.7 7.5 10.8 1.9 20.1 8.2 43.7 8.1 2.0 9.0 0.0 5.1 13.6 5.0 7.8 14.8 6.7 3.8 10.7 9.9 17.3 6.3 ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 61.7;Theca cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" 3.1 9.1 1.3 1.5 1.3 0.9 3.4 1.1 2.6 4.5 0.9 6.7 4.8 3.7 0.2 6.4 3.7 0.5 4.1 1.4 1.1 4.3 6.4 2.8 1.1 1.4 1.1 4.5 5.0 0.8 3.5 0.6 1.3 4.1 0.7 0.5 4.1 0.8 4.0 5.2 8.4 0.4 0.9 5.7 4.4 6.7 1.2 1.1 3.6 0.7 0.5 4.0 4.2 1.2 2.5 3.1 0.7 2.1 0.5 0.5 3.7 2.2 1.2 1.8 0.7 3.6 2.7 1.1 1.5 0.5 0.6 3.2 0.1 2.2 0.1 2.8 1.0 2.9 2.6 3.9 1.6 0.7 2.2 1.0 1.4 0.6 0.7 0.9 1.2 2.1 1.9 1.9 0.9 6.9 2.2 2.9 0.4 2.3 2.3 2.8 1.0 2.0 1.2 2.3 0.4 1.1 3.1 2.4 1.8 0.5 2.1 1.9 0.8 0.8 3.2 2.2 1.5 0.9 0.3 1.0 1.9 2.5 1.3 0.9 2.0 1.2 1.1 2.7 1.3 0.9 1.3 0.8 3.2 2.7 1.3 0.7 0.4 1.0 2.7 2.0 2.1 1.3 1.3 1.3 1.1 2.6 1.4 1.1 1.4 1.1 1.3 0.9 1.2 1.2 5.8 3.2 1.7 4.9 6.5 4.1 3.3 10.2 2.2 10.3 5.0 6.1 2.3 7.2 6.9 5.5 16.7 4.3 6.6 33.5 3.9 9.3 8.2 3.7 4.2 5.0 8.4 3.0 7.6 7.1 11.2 4.5 20.4 4.8 8.9 16.2 2.5 8.2 8.0 3.3 8.3 31.2 12.2 5.5 4.3 11.3 5.9 5.0 3.6 2.8 9.1 6.4 7.2 4.0 2.4 9.5 16.8 7.2 3.7 2.7 61.7 6.9 9.5 16.3 13.1 2.5 4.4 26.5 19.2 4.7 5.1 2.5 4.8 42.3 25.4 3.1 CPSF1 CPSF160 ENSG00000071894 "Cleavage and polyadenylation specific factor 1" Q10570 8 144393229-144409335 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065167, HPA068906" Enhanced Nucleoplasm No No "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "HPA065167: AB_2685426, HPA068906: AB_2686055" "unprognostic (6.37e-2)" "unprognostic (7.72e-2)" "unprognostic (2.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.93e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (1.05e-1)" "unprognostic (2.00e-3)" "unprognostic (6.45e-2)" "unprognostic (7.54e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.54e-5)" "unprognostic (2.40e-1)" "unprognostic (1.91e-1)" "unprognostic (7.90e-2)" "unprognostic (9.66e-3)" 39.1 52.0 16.2 11.0 16.6 20.4 45.5 15.9 23.3 53.5 16.2 54.8 27.4 48.8 3.8 49.2 49.1 9.0 44.9 15.9 14.9 52.2 76.3 43.3 12.3 16.8 14.9 56.6 88.6 6.1 78.0 6.8 17.1 61.7 4.2 5.2 49.6 7.6 41.0 55.3 68.1 5.7 14.6 70.5 68.9 132.0 15.6 15.0 52.9 5.2 6.8 41.2 44.0 16.2 21.4 29.4 26.3 27.7 13.8 11.0 25.7 19.6 12.4 15.8 16.3 29.8 27.0 24.6 18.7 14.8 10.7 19.1 14.9 16.7 4.4 22.2 43.0 48.3 37.4 48.6 11.7 18.6 28.8 12.1 6.9 14.5 8.5 9.5 21.2 40.1 41.1 20.4 8.0 90.7 48.8 38.6 15.9 17.9 41.0 34.7 10.6 19.9 17.0 31.1 21.3 21.1 25.4 15.7 14.8 7.4 27.9 20.5 18.4 10.8 41.3 23.9 22.3 12.1 10.2 23.3 14.6 31.0 13.1 3.8 5.1 3.3 4.8 6.1 5.1 4.0 5.2 5.1 5.7 4.8 4.5 4.3 0.9 4.0 6.2 2.6 6.7 4.2 16.2 16.6 15.9 23.3 15.9 14.9 16.8 14.9 17.1 14.6 15.6 16.2 10.1 16.0 22.5 10.1 9.5 10.1 4.0 6.6 6.2 9.6 15.1 16.9 8.3 20.0 10.7 9.2 12.5 10.1 14.5 26.4 1.9 9.5 19.5 9.6 7.8 11.7 13.1 15.8 9.4 11.5 11.5 10.7 21.9 11.8 14.0 20.7 8.9 8.1 15.1 8.4 6.9 28.6 8.2 12.4 12.4 40.4 14.0 11.7 14.2 3.7 11.9 5.0 10.3 5.5 6.5 10.5 8.8 16.1 17.9 4.1 24.0 6.2 11.7 14.4 6.6 7.7 9.0 36.5 23.1 12.2 12.4 7.3 11.5 7.6 30.3 4.3 SLC39A4 "AEZ, AWMS2, ZIP4" ENSG00000147804 "Solute carrier family 39 member 4" Q6P5W5 8 144409742-144416844 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 88.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 406.4;Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "CAPAN-2: 36.4;Hep G2: 97.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "unprognostic (2.59e-1)" "unprognostic (2.35e-3)" "unprognostic (9.16e-2)" "unprognostic (3.84e-2)" "unprognostic (5.63e-3)" "unprognostic (1.46e-1)" "unprognostic (5.40e-2)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (3.28e-2)" "unprognostic (1.41e-2)" "unprognostic (1.24e-1)" "prognostic favorable (9.04e-4)" "unprognostic (2.78e-2)" "unprognostic (3.97e-1)" "unprognostic (9.04e-3)" "unprognostic (1.87e-1)" 0.1 0.2 0.1 1.4 0.2 0.5 0.3 0.0 0.7 0.7 0.0 33.1 88.1 0.4 0.1 0.2 0.9 0.5 0.0 0.2 0.0 18.4 1.3 3.1 0.1 0.0 0.0 3.3 1.4 0.0 0.2 1.0 0.0 1.3 0.5 0.0 1.2 0.3 0.0 0.5 74.9 0.1 0.0 0.7 2.9 1.3 0.0 0.0 3.9 0.0 0.0 0.6 0.6 0.0 2.3 0.2 0.0 0.1 0.0 0.0 2.5 0.1 0.0 0.0 0.0 2.1 36.4 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 6.4 0.8 1.6 0.6 97.4 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.5 2.2 0.0 1.7 0.0 0.4 0.1 0.5 0.1 0.4 0.0 1.1 0.0 0.4 0.9 1.9 0.2 0.4 0.1 0.4 1.7 0.1 0.0 0.1 0.2 0.0 0.0 0.9 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 19.2 24.8 0.3 21.3 18.7 36.6 46.9 38.7 0.2 45.0 50.3 7.4 20.0 24.1 42.3 0.0 17.0 15.4 112.8 50.9 40.0 1.4 41.8 12.9 10.9 42.6 26.3 1.0 42.9 69.7 16.8 29.6 51.9 37.4 8.5 8.9 27.4 32.1 3.3 0.2 95.0 30.5 18.2 21.0 2.0 8.1 23.5 21.4 0.0 25.9 11.3 23.7 0.0 0.1 75.6 135.0 6.4 31.9 60.8 406.4 230.3 26.9 1.0 6.6 7.5 11.1 2.9 33.1 46.4 30.0 11.2 15.4 23.2 98.2 46.3 VPS28 ENSG00000160948 "VPS28 subunit of ESCRT-I" Q9UK41 8 144423601-144428563 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.8;SH-SY5Y: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024688, HPA024745" Supported NA NA 63000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 53: Intestinal epithelial cells - Unknown function" "HPA024688: AB_1858766, HPA024745: AB_1858765" "unprognostic (2.87e-2)" "unprognostic (1.87e-1)" "unprognostic (1.27e-1)" "prognostic favorable (9.93e-4)" "unprognostic (3.18e-1)" "unprognostic (2.03e-1)" "unprognostic (9.29e-2)" "unprognostic (7.94e-3)" "unprognostic (1.54e-2)" "unprognostic (2.00e-2)" "unprognostic (7.92e-2)" "unprognostic (6.85e-2)" "unprognostic (3.15e-1)" "unprognostic (2.93e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (2.37e-2)" 132.8 137.6 0.1 0.0 0.1 0.0 132.9 0.0 0.3 147.7 0.0 150.5 0.0 133.7 0.0 138.0 127.3 0.1 177.5 0.1 0.2 173.8 162.7 123.1 0.1 0.1 0.2 159.6 146.5 0.0 129.3 0.1 0.5 136.3 0.0 0.7 119.7 0.2 197.7 150.4 140.0 0.0 0.0 144.9 154.1 151.8 0.1 0.0 144.5 1.1 0.0 128.7 135.4 0.2 0.2 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.2 0.1 0.2 0.5 0.0 0.1 0.2 189.6 112.2 128.6 32.3 126.9 103.2 138.6 180.0 105.9 91.9 139.0 171.2 70.1 131.5 133.9 169.2 60.5 166.4 126.6 387.2 273.9 264.5 208.6 130.4 131.5 149.7 172.7 139.3 20.1 251.1 160.9 142.9 154.9 164.9 185.5 191.5 142.1 141.4 250.7 57.2 25.9 256.8 128.1 178.9 155.9 183.1 198.8 172.1 188.5 22.5 285.8 168.6 144.1 20.1 32.3 287.3 462.2 156.1 112.8 128.9 561.9 526.5 134.6 121.8 157.8 140.0 206.5 232.1 127.2 142.7 133.5 112.7 160.9 275.7 206.0 168.8 TONSL "IKBR, NFKBIL2" ENSG00000160949 "Tonsoku like, DNA repair protein" Q96HA7 8 144428775-144444440 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 76.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024679, HPA046494" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Nuclear bodies" "HPA024679: AB_1854441, HPA046494: AB_2679673" "unprognostic (6.68e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-1)" "unprognostic (2.88e-2)" "unprognostic (7.35e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (2.84e-4)" "unprognostic (1.04e-3)" "unprognostic (7.81e-2)" "unprognostic (4.39e-2)" "unprognostic (3.38e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.62e-7)" "unprognostic (3.24e-2)" "unprognostic (1.78e-1)" "unprognostic (9.11e-3)" "unprognostic (7.96e-2)" 1.0 2.1 0.4 2.5 0.4 8.5 1.3 0.4 1.3 1.7 0.0 3.4 3.5 1.6 0.2 3.9 1.4 0.6 1.4 0.3 0.3 1.4 1.7 1.3 2.3 1.3 0.6 1.7 1.5 0.4 0.9 1.5 1.1 1.6 0.8 0.1 1.5 0.8 0.5 3.3 4.4 0.6 0.1 3.9 2.2 3.8 0.8 2.3 2.4 0.1 1.4 2.3 2.1 0.3 21.2 18.6 13.7 21.7 1.0 1.7 33.0 17.6 3.4 10.4 8.1 15.0 17.9 19.6 17.5 2.7 4.9 14.2 13.4 10.7 2.3 20.2 26.6 46.5 26.1 15.9 0.6 14.3 28.1 1.7 1.5 10.9 2.1 2.6 5.0 26.5 53.0 14.3 4.2 43.4 35.5 24.5 19.4 20.4 26.7 42.6 8.9 20.3 5.9 22.6 22.9 13.0 18.4 12.3 7.8 5.2 17.6 13.2 5.9 12.7 52.3 14.5 21.7 5.0 9.9 12.0 12.3 30.2 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.4 1.3 0.3 0.3 1.3 0.6 1.1 0.1 0.8 0.3 2.5 6.4 22.4 1.6 2.9 8.9 5.2 1.0 1.2 3.1 3.5 2.9 2.3 8.6 3.7 1.8 2.1 4.1 1.3 20.2 0.0 0.9 0.4 4.3 2.7 4.3 2.4 7.2 2.4 1.0 5.3 3.8 11.7 6.1 2.5 8.5 2.9 11.4 4.5 1.7 1.0 14.6 0.0 0.9 16.7 0.7 0.3 3.0 14.2 1.9 1.2 1.1 1.0 0.5 0.8 1.2 7.1 1.2 4.0 3.9 76.5 7.7 4.1 3.0 6.6 6.4 2.8 4.6 7.8 3.4 11.2 1.2 3.1 3.3 15.9 3.9 CYHR1 "CHRP, KIAA0496, MGC13010" ENSG00000187954 "Cysteine and histidine rich 1" Q6ZMK1 8 144449582-144465667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053653, HPA059543" Approved Enhanced Nucleoplasm NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 5: Muller glia cells - Visual perception" Nucleoplasm "HPA053653: AB_2682219, HPA059543: AB_2684056" "unprognostic (1.04e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (1.58e-2)" "unprognostic (8.28e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (4.02e-2)" "unprognostic (2.63e-1)" "unprognostic (2.13e-1)" "unprognostic (7.08e-3)" "unprognostic (1.46e-1)" "unprognostic (5.33e-2)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-1)" "unprognostic (1.54e-2)" 33.6 57.9 61.2 9.2 60.3 11.1 37.1 58.2 76.1 50.5 57.1 46.8 15.8 41.0 22.8 34.7 43.1 16.0 58.9 61.7 59.5 43.1 48.8 26.6 15.3 63.7 59.9 44.7 60.9 28.9 67.5 10.2 58.6 70.5 8.8 11.2 40.5 27.6 45.9 41.5 30.0 12.0 60.5 35.0 42.1 69.8 59.6 13.7 44.1 22.6 8.5 48.9 40.3 61.2 23.0 27.6 18.3 22.6 30.8 20.7 22.9 15.5 15.9 14.6 18.4 12.8 30.6 10.4 32.5 23.3 18.1 34.0 14.4 22.6 5.6 25.3 23.9 23.6 33.7 22.1 42.9 6.0 12.4 35.6 29.9 18.2 22.7 32.2 16.9 29.0 34.8 27.7 14.0 51.5 28.9 16.6 12.0 34.5 57.5 27.3 7.7 29.6 22.5 19.5 26.7 16.4 33.5 27.9 36.6 13.9 37.5 23.8 20.1 18.4 21.5 20.5 15.6 14.0 9.9 8.4 26.5 20.2 15.2 2.9 11.7 7.0 9.5 8.4 15.5 12.9 11.9 7.8 12.7 14.0 22.2 12.5 5.8 5.3 9.5 27.0 5.0 9.6 61.2 60.3 58.2 76.1 61.7 59.5 63.7 59.9 58.6 60.5 59.6 61.2 32.6 35.3 26.5 52.5 18.5 30.5 46.2 31.8 43.9 75.6 68.7 69.6 19.0 45.8 28.7 58.8 25.0 29.2 33.3 43.2 43.0 28.1 12.5 37.2 37.3 28.9 33.7 23.4 45.9 28.7 20.1 36.4 32.6 32.7 5.1 42.9 37.9 45.6 25.6 90.9 39.4 44.0 36.7 26.7 23.2 44.1 50.7 23.0 26.6 18.7 31.0 120.5 22.6 31.7 37.2 23.2 42.9 39.9 26.2 48.5 47.6 35.0 41.7 59.0 39.5 37.4 35.5 45.8 32.3 36.8 38.8 16.7 24.3 82.2 47.3 35.6 KIFC2 ENSG00000167702 "Kinesin family member C2" Q96AC6 8 144466043-144474202 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 113.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 59.8;Gastric mucus-secreting cells: 38.7;Inhibitory neurons: 39.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029264 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Cytosol "HPA029264: AB_10609999" "unprognostic (2.03e-1)" "unprognostic (1.28e-3)" "unprognostic (3.87e-3)" "unprognostic (4.12e-3)" "unprognostic (4.28e-2)" "unprognostic (1.48e-1)" "unprognostic (2.20e-2)" "unprognostic (3.41e-2)" "unprognostic (2.12e-1)" "unprognostic (9.95e-2)" "unprognostic (2.39e-2)" "unprognostic (4.48e-2)" "unprognostic (1.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.05e-1)" "unprognostic (8.13e-2)" "unprognostic (2.71e-2)" 12.3 17.2 68.7 6.2 78.3 7.2 14.0 58.3 113.7 24.5 33.2 26.5 11.9 11.4 6.7 45.0 15.3 6.1 10.1 74.7 42.9 32.9 20.6 17.2 7.3 54.9 41.1 13.0 24.9 9.6 45.0 3.2 54.6 31.5 6.3 3.8 19.1 8.0 4.2 75.0 24.4 2.5 35.7 27.6 19.7 25.8 46.4 5.4 24.2 1.7 4.8 22.2 31.8 63.9 13.5 12.7 6.1 13.2 8.7 5.2 13.2 5.3 6.4 4.7 4.6 4.9 18.1 11.6 3.6 5.0 7.9 24.2 6.1 8.1 2.0 10.2 3.7 8.6 34.5 6.6 11.1 2.6 23.4 6.7 28.3 4.7 6.1 21.8 3.0 14.7 7.0 15.9 3.6 25.4 10.3 7.1 0.9 16.5 15.2 24.1 0.3 8.8 19.9 23.1 18.4 16.4 6.2 19.3 6.9 4.3 50.4 5.0 7.6 9.0 22.9 9.4 7.7 6.3 2.9 3.9 17.6 12.3 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.7 78.3 58.3 113.7 74.7 42.9 54.9 41.1 54.6 35.7 46.4 63.9 3.7 9.6 11.3 35.3 4.9 6.0 3.0 2.1 6.2 16.2 7.9 5.8 0.8 7.2 5.2 14.7 6.2 2.0 12.1 29.1 1.9 3.5 13.2 6.8 4.4 2.0 23.4 3.2 59.8 1.4 2.0 2.0 38.7 13.8 8.2 3.3 2.5 8.7 2.7 15.2 39.7 12.2 0.0 5.3 9.1 8.0 7.8 6.4 3.6 12.2 3.5 7.5 3.1 8.5 6.9 2.2 18.5 3.0 7.0 3.4 11.3 5.1 4.5 4.6 0.0 1.8 2.9 7.3 7.5 10.6 11.4 3.0 8.0 6.6 18.0 3.3 FOXH1 FAST1 ENSG00000160973 "Forkhead box H1" O75593 8 144473412-144475849 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 2.1;skin 1: 1.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 3.4;Spermatogonia: 1.7" "Cancer enriched" "Detected in some" 26 "testis cancer: 23.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "NTERA-2: 26.6;SuSa: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" "unprognostic (1.62e-1)" "unprognostic (8.26e-2)" "unprognostic (4.70e-2)" "unprognostic (2.23e-2)" "unprognostic (2.10e-1)" "unprognostic (1.65e-1)" "unprognostic (1.09e-2)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (6.20e-2)" "unprognostic (3.99e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-8)" "unprognostic (1.03e-1)" "unprognostic (3.39e-2)" "unprognostic (3.99e-1)" "unprognostic (9.35e-3)" 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.0 1.1 0.4 0.0 0.0 0.4 0.0 0.2 0.3 0.1 0.2 0.5 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.2 2.1 0.2 0.0 0.0 1.4 0.7 0.0 0.0 0.2 0.5 1.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.2 0.4 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.1 0.1 1.4 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.3 0.4 0.0 0.0 0.7 0.0 0.3 26.6 0.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.4 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.3 1.7 0.0 0.1 0.0 0.1 0.4 0.7 0.1 PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 208.9;Proximal enterocytes: 440.8;Proximal tubular cells: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 49.9" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA023755: AB_1854268" "unprognostic (9.63e-2)" "unprognostic (4.51e-2)" "unprognostic (5.45e-3)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (3.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.65e-1)" "unprognostic (3.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.45e-2)" "unprognostic (2.79e-2)" 6.1 15.0 10.2 4.7 8.6 3.8 8.2 4.3 15.0 10.5 16.7 25.1 27.1 10.5 1.6 9.8 18.9 3.1 9.6 12.9 8.9 26.7 23.5 10.8 2.9 10.2 10.4 7.9 17.7 7.4 36.9 1.7 7.1 15.5 2.4 2.9 11.6 5.6 6.3 9.0 24.6 1.6 8.1 8.0 14.1 33.3 10.3 2.4 27.0 1.0 1.0 9.1 6.7 5.1 30.4 24.3 3.9 15.1 1.6 2.7 19.3 8.2 5.1 6.3 5.1 6.4 21.2 5.0 21.1 3.0 5.6 19.8 2.0 6.7 1.0 10.3 11.9 6.0 26.4 6.8 4.7 4.3 7.9 2.7 8.9 7.3 2.1 4.1 4.5 8.2 24.0 6.1 2.3 49.9 15.3 19.9 7.4 15.6 30.3 15.9 1.9 10.1 5.7 10.0 12.5 23.9 14.9 13.7 13.0 1.0 32.3 9.1 7.7 7.1 33.2 19.8 15.8 4.0 4.3 1.8 22.8 8.3 6.5 0.0 0.8 0.0 1.0 1.2 0.9 0.8 0.8 1.0 1.2 0.1 0.5 1.1 0.2 0.2 1.7 0.7 0.6 0.8 10.2 8.6 4.3 15.0 12.9 8.9 10.2 10.4 7.1 8.1 10.3 5.1 7.9 3.2 15.4 28.1 6.2 43.2 36.2 47.6 54.1 25.0 78.3 82.0 85.8 157.3 24.6 40.5 14.6 7.2 6.0 135.9 121.3 33.7 12.6 43.8 15.6 13.3 51.6 6.1 7.8 41.6 24.3 13.3 70.3 24.2 3.8 16.4 12.8 208.9 6.1 30.3 7.6 98.1 26.4 7.0 27.1 14.4 22.7 9.8 8.8 5.6 3.8 102.8 5.2 6.6 2.8 29.3 109.8 15.4 5.9 40.0 440.8 404.2 59.8 50.9 6.6 17.2 17.3 52.9 28.7 77.8 61.8 6.7 7.1 69.2 116.0 28.3 GPT "ALT1, GPT1" ENSG00000167701 "Glutamic--pyruvic transaminase" P24298 8 144502973-144507174 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 179.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 176.9;Hepatocytes: 237.3;Paneth cells: 88.4;Proximal enterocytes: 139.7;Proximal tubular cells: 164.9" "Cancer enriched" "Detected in many" 7 "liver cancer: 38.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;Karpas-707: 2.8;U-266/70: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031059, HPA031060, CAB032997, CAB032999" Enhanced NA NA 17000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "CAB032997: AB_2261949, CAB032999: AB_2095427, HPA031059: AB_10600214, HPA031060: AB_10602178" "unprognostic (8.22e-3)" "unprognostic (2.52e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (1.37e-2)" "prognostic favorable (1.47e-5)" "unprognostic (9.42e-2)" "unprognostic (2.19e-1)" "unprognostic (1.32e-1)" "unprognostic (4.41e-1)" "unprognostic (9.22e-2)" "prognostic favorable (2.19e-4)" "unprognostic (2.83e-2)" "unprognostic (2.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.98e-2)" 22.6 2.4 2.2 4.6 1.9 2.3 12.5 3.3 4.7 0.7 3.5 36.0 18.3 0.5 0.4 2.4 1.3 2.4 40.3 2.1 0.4 13.9 179.6 0.4 0.3 0.8 0.5 1.1 10.3 1.4 2.9 0.1 0.6 1.8 5.8 0.6 14.6 1.2 50.1 17.1 18.0 0.4 0.2 0.6 15.0 2.6 0.9 0.0 0.9 24.3 0.2 0.6 1.3 0.9 0.2 0.8 0.2 0.5 0.4 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.9 0.4 0.3 0.0 0.0 2.1 0.0 0.0 0.0 0.7 1.3 0.3 1.5 2.5 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.4 0.2 2.8 0.0 1.3 0.4 0.4 0.3 0.6 0.5 0.5 0.1 1.5 0.0 0.9 0.5 0.8 0.2 0.7 0.1 0.1 1.9 0.1 0.2 0.1 0.6 0.7 0.1 2.9 0.2 0.2 0.4 0.9 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.2 1.9 3.3 4.7 2.1 0.4 0.8 0.5 0.6 0.2 0.9 0.9 0.2 0.0 0.0 14.4 5.3 1.7 1.3 1.2 0.6 0.9 14.1 4.6 8.5 34.3 1.8 7.3 0.0 0.0 0.4 176.9 21.5 1.1 16.5 0.5 0.4 1.1 2.4 43.2 0.8 2.4 3.3 0.3 51.0 0.7 8.9 0.3 14.3 237.3 0.1 3.3 0.5 30.4 0.0 14.4 2.1 48.1 0.6 1.2 1.8 1.0 0.1 15.6 0.0 2.0 0.0 1.3 88.4 0.4 0.1 1.2 139.7 164.9 0.5 2.0 0.0 2.0 0.4 1.0 0.6 2.4 4.5 0.0 1.8 0.4 62.1 1.6 MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" 8.4 22.6 9.2 3.4 8.0 1.8 10.7 7.2 12.0 8.0 6.4 22.6 13.5 8.3 4.1 16.1 8.4 2.5 21.8 8.8 6.7 27.5 44.6 7.6 2.8 10.8 7.1 6.7 18.8 12.3 17.8 1.5 9.4 19.2 3.3 1.5 19.6 5.4 23.5 17.8 15.4 1.2 5.4 10.8 15.6 6.3 9.5 2.3 23.9 6.1 1.7 9.7 9.2 7.0 16.2 21.7 5.4 4.6 5.9 4.4 17.6 5.1 5.3 2.8 4.2 7.3 11.2 23.3 17.3 4.8 5.6 15.5 2.5 12.1 0.5 11.0 44.0 7.5 19.9 18.3 11.0 3.6 9.9 6.5 22.3 1.8 7.7 12.1 7.3 16.0 14.2 6.2 6.8 53.7 9.0 18.9 14.3 22.9 36.9 9.9 2.8 41.7 13.2 9.5 39.1 19.7 13.0 31.6 11.3 3.4 33.1 5.2 7.9 3.7 9.9 4.2 7.1 6.0 2.6 8.1 8.0 11.3 6.5 1.8 7.4 3.8 3.9 6.7 3.7 4.9 3.9 4.0 11.0 2.5 3.5 3.6 0.4 3.8 3.6 19.2 4.4 4.1 9.2 8.0 7.2 12.0 8.8 6.7 10.8 7.1 9.4 5.4 9.5 7.0 3.0 3.2 3.7 6.5 8.0 6.0 10.3 17.3 8.6 8.2 18.8 14.5 9.3 30.0 11.8 27.6 10.4 16.5 3.7 31.3 37.2 17.6 0.6 5.1 3.9 3.8 19.8 8.2 6.2 21.0 15.0 4.0 16.3 7.4 0.0 9.7 3.3 27.6 15.5 16.8 6.2 19.6 24.4 7.0 3.2 1.8 4.4 6.4 8.8 1.9 7.5 14.8 6.2 2.5 3.8 15.7 19.1 4.9 14.8 12.8 33.1 63.6 3.2 10.0 0.0 7.0 3.4 3.8 11.7 19.0 7.1 9.3 3.5 16.9 27.1 9.8 RECQL4 RecQ4 ENSG00000160957 "RecQ like helicase 4" O94761 8 144511288-144517845 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase" "Cancer-related genes, Cataract, Craniosynostosis, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.4;testis: 22.4" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.5;Spermatogonia: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "CAB017800, HPA025821" Supported Enhanced Nucleoplasm NA Yes "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "CAB017800: , HPA025821: AB_1856168" "unprognostic (5.92e-2)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (9.17e-2)" "unprognostic (3.17e-2)" "prognostic unfavorable (1.91e-4)" "unprognostic (1.12e-2)" "unprognostic (4.12e-2)" "unprognostic (7.53e-2)" "unprognostic (2.65e-2)" "unprognostic (4.26e-2)" "unprognostic (1.12e-3)" "unprognostic (8.82e-3)" "unprognostic (1.74e-1)" "unprognostic (2.24e-1)" "unprognostic (1.34e-1)" 1.7 1.8 3.0 5.8 3.7 25.4 2.0 7.7 7.0 2.9 0.1 4.7 6.0 2.5 0.4 13.3 2.1 2.1 1.8 2.6 1.6 2.5 2.7 2.3 6.8 6.9 2.3 2.7 3.1 0.7 3.1 2.5 7.4 8.6 1.6 1.5 5.8 0.8 2.5 10.1 5.2 1.0 1.7 6.5 3.2 22.4 4.1 7.4 3.4 0.5 2.5 2.5 3.1 3.6 33.7 58.8 27.0 57.1 1.6 2.6 47.1 33.2 5.9 24.2 20.2 58.4 48.4 22.8 21.5 5.6 14.2 40.1 18.0 14.2 6.6 40.3 68.6 82.4 118.5 44.3 0.5 21.2 65.7 3.3 2.1 27.1 5.5 3.4 6.8 45.4 83.3 28.9 8.5 104.1 77.3 56.9 18.8 27.8 69.5 80.0 21.2 37.9 6.7 35.8 52.9 32.0 45.2 37.3 12.1 7.4 45.5 45.7 9.2 38.9 117.4 47.3 62.6 16.0 18.1 39.3 22.4 64.6 39.9 0.0 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 3.7 7.7 7.0 2.6 1.6 6.9 2.3 7.4 1.7 4.1 3.6 0.7 0.0 0.0 2.0 2.2 1.5 0.7 0.9 1.2 2.7 3.7 2.7 1.8 1.5 0.5 0.0 4.2 3.9 1.0 5.9 0.0 0.5 3.9 2.1 0.9 0.7 0.0 6.1 2.0 0.4 8.1 1.8 4.6 2.0 0.0 8.8 0.0 0.7 3.6 0.0 1.6 4.1 0.0 0.6 1.1 7.4 1.2 1.0 0.0 0.0 0.3 0.3 1.0 0.0 0.8 0.3 0.2 1.5 9.1 0.7 0.7 0.5 0.7 1.7 0.0 1.4 1.2 23.5 20.6 6.6 1.0 1.5 1.2 0.5 7.0 0.7 LRRC14 "KIAA0014, LRRC14A" ENSG00000160959 "Leucine rich repeat containing 14" Q15048 8 144517992-144525172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021047 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "HPA021047: AB_1853298" "unprognostic (7.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (7.05e-3)" "unprognostic (1.83e-1)" "unprognostic (7.58e-2)" "unprognostic (6.39e-3)" "unprognostic (1.93e-1)" "unprognostic (3.96e-2)" "unprognostic (2.28e-1)" "prognostic favorable (1.78e-4)" "unprognostic (3.31e-1)" "unprognostic (1.52e-1)" "unprognostic (7.25e-2)" "unprognostic (1.77e-1)" "unprognostic (6.93e-2)" "unprognostic (1.04e-3)" 8.6 13.1 10.4 6.4 9.9 7.5 9.7 14.9 11.8 15.6 3.1 15.0 7.5 16.2 5.8 14.1 13.1 5.7 10.9 11.8 7.1 11.8 11.9 9.8 9.3 9.9 9.0 12.9 16.2 8.3 16.0 4.9 9.4 19.4 5.3 3.3 12.0 8.1 11.4 13.1 13.3 5.6 9.1 14.5 14.2 11.7 9.1 7.1 16.8 5.0 6.6 14.6 12.2 10.8 18.2 36.2 9.7 15.8 10.2 8.3 13.8 15.9 6.8 12.6 10.8 15.9 21.6 14.5 16.5 11.9 7.7 19.4 15.3 15.8 5.7 19.7 34.8 21.9 42.7 6.9 9.5 9.3 17.3 10.1 13.3 12.7 6.2 10.4 10.9 16.6 29.2 17.1 12.4 22.3 34.9 12.2 7.9 15.8 51.8 29.6 8.0 20.9 7.6 15.6 26.4 14.7 24.2 19.3 11.2 5.7 29.8 10.3 11.8 21.4 37.6 19.0 23.7 9.5 6.0 18.2 20.1 21.4 13.4 1.6 7.2 1.6 8.3 6.8 8.0 7.8 6.2 7.8 7.2 7.9 6.7 5.6 3.8 11.4 6.0 8.4 6.7 8.0 10.4 9.9 14.9 11.8 11.8 7.1 9.9 9.0 9.4 9.1 9.1 10.8 6.3 6.4 3.1 6.5 10.9 6.4 5.0 3.4 9.1 11.5 9.8 9.5 4.6 14.3 6.0 9.2 2.1 6.9 6.9 10.3 5.9 5.4 2.8 6.3 6.8 7.3 5.4 8.4 3.8 8.2 6.6 5.8 10.2 6.4 7.0 11.2 8.9 9.8 7.7 11.8 2.8 8.1 2.0 6.0 4.0 3.9 7.5 4.4 1.8 8.4 7.4 9.5 9.2 6.6 3.3 7.3 4.9 7.9 11.1 8.3 6.0 7.4 7.5 7.4 6.6 5.0 6.7 29.3 22.0 6.6 5.8 5.5 9.4 16.8 11.9 3.9 LRRC24 LRRC14OS ENSG00000254402 "Leucine rich repeat containing 24" Q50LG9 8 144522388-144527033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 13.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 103.2;Cone photoreceptor cells: 73.0;Horizontal cells: 30.3;Late spermatids: 69.0;Rod photoreceptor cells: 86.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.6;SCLC-21H: 2.7;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028171, HPA052250" Enhanced Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA028171: AB_2672504, HPA052250: AB_2681774" "unprognostic (1.75e-1)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "unprognostic (3.63e-2)" 2.1 3.6 6.2 0.1 6.4 0.3 2.3 4.1 7.8 5.0 0.8 3.1 0.3 4.4 0.2 3.8 5.4 0.1 1.9 5.4 9.0 3.7 3.2 2.7 0.2 10.0 8.3 6.1 3.0 1.2 13.3 0.2 6.5 11.5 0.1 1.4 1.5 0.6 1.2 1.8 2.6 0.2 4.5 2.1 2.4 3.0 5.3 0.3 3.4 0.1 0.0 2.9 3.2 4.8 0.2 0.5 0.4 0.9 0.4 0.3 1.1 0.3 0.4 0.4 0.3 0.1 1.0 0.5 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.3 0.6 0.2 0.3 0.0 0.6 0.4 0.2 0.3 0.0 0.2 0.2 0.5 0.6 0.1 0.0 2.6 0.7 1.0 0.1 0.1 0.5 1.1 0.0 0.4 0.1 0.3 2.7 7.4 0.2 0.1 0.2 0.0 2.3 0.8 0.0 0.1 0.7 0.3 0.1 0.5 0.1 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.4 4.1 7.8 5.4 9.0 10.0 8.3 6.5 4.5 5.3 4.8 0.7 0.0 2.3 8.5 1.0 0.9 0.5 0.0 0.0 103.2 2.3 2.8 0.0 1.5 0.7 1.8 73.0 0.6 0.5 2.1 3.9 0.2 23.7 1.5 1.5 1.1 10.7 0.8 3.8 0.2 0.4 1.4 3.1 1.6 0.0 4.8 0.7 3.1 0.5 30.3 6.5 2.7 0.0 0.8 1.7 69.0 2.8 0.8 5.4 1.0 0.2 18.6 1.0 4.5 2.2 0.3 1.9 3.0 1.2 1.8 1.9 3.6 0.1 86.2 0.0 2.9 1.9 11.2 3.5 1.7 0.4 0.4 0.6 8.4 1.9 0.9 C8orf82 MGC70857 ENSG00000213563 "Chromosome 8 open reading frame 82" Q6P1X6 8 144525733-144529132 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 138.9;Proximal tubular cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "PC-3: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB034331 Uncertain Approved Nucleoplasm NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "CAB034331: AB_1565393" "unprognostic (3.56e-1)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (1.63e-2)" "unprognostic (8.60e-2)" "unprognostic (6.31e-3)" "unprognostic (1.95e-1)" "unprognostic (4.57e-2)" "unprognostic (3.82e-1)" "unprognostic (1.22e-1)" "unprognostic (3.61e-1)" "unprognostic (4.09e-2)" "prognostic favorable (1.70e-5)" "unprognostic (5.72e-3)" "unprognostic (3.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.87e-3)" 10.6 14.6 9.0 4.5 8.6 2.8 11.4 11.1 10.5 14.7 4.2 14.1 11.1 11.8 2.6 16.7 11.9 3.8 17.0 8.2 7.5 16.2 35.6 8.6 3.8 9.4 8.1 15.1 13.2 6.6 12.2 3.3 8.6 26.3 3.8 4.6 11.6 5.5 12.0 9.1 11.7 2.8 7.2 9.9 12.3 7.4 8.4 4.5 12.6 3.5 2.4 15.0 11.8 11.5 6.8 16.8 9.8 7.9 4.0 3.4 8.2 7.2 3.9 3.9 3.9 8.3 11.2 11.9 11.4 4.5 3.3 8.1 2.2 2.5 1.4 9.0 25.7 23.0 10.4 15.6 4.2 3.5 10.8 5.1 5.5 2.5 2.5 6.4 2.7 6.6 19.1 5.9 2.9 35.7 8.9 14.2 5.3 10.1 46.6 9.9 3.3 5.8 6.1 10.1 33.3 27.3 11.0 7.8 7.1 3.3 14.3 7.1 14.6 7.5 28.7 8.4 5.3 4.2 2.8 9.8 9.9 4.3 7.3 0.1 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 9.0 8.6 11.1 10.5 8.2 7.5 9.4 8.1 8.6 7.2 8.4 11.5 12.2 3.2 6.9 0.3 12.9 15.9 49.6 1.9 23.3 30.4 39.6 38.6 17.9 18.6 1.9 16.5 14.6 33.4 13.0 46.3 138.9 5.8 16.8 10.3 22.1 12.3 34.2 14.9 0.1 7.7 35.1 18.5 19.4 26.0 5.7 16.3 9.7 69.8 18.6 28.6 0.1 31.9 2.0 16.1 16.1 21.4 24.2 15.2 33.8 0.0 7.5 28.0 13.4 0.0 0.1 6.7 22.1 20.3 16.3 55.6 35.4 99.1 0.4 35.8 32.9 21.1 23.0 24.4 18.8 36.9 20.9 25.2 13.1 34.5 34.6 43.3 ARHGAP39 "CrGAP, KIAA1688, Vilse" ENSG00000147799 "Rho GTPase activating protein 39" Q9C0H5 8 144529179-144605816 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 34.3;Endometrial ciliated cells: 31.4;Excitatory neurons: 41.7;Inhibitory neurons: 33.1;Oligodendrocytes: 30.8;Respiratory ciliated cells: 27.6;Rod photoreceptor cells: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044491 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA044491: AB_10794775" "unprognostic (3.42e-2)" "unprognostic (2.65e-2)" "unprognostic (9.85e-2)" "unprognostic (4.17e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-1)" "unprognostic (1.74e-7)" "unprognostic (1.89e-2)" "unprognostic (3.00e-1)" "unprognostic (2.02e-1)" "unprognostic (6.90e-3)" "unprognostic (1.53e-1)" "unprognostic (5.19e-2)" "unprognostic (1.26e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (9.97e-2)" 1.6 3.9 4.3 0.8 5.2 0.0 3.4 2.3 9.4 4.9 1.2 4.5 1.7 2.8 0.8 5.0 8.2 0.7 1.9 8.5 2.3 4.9 1.6 2.7 0.3 8.4 5.9 2.6 5.2 1.3 9.9 0.7 5.5 4.2 0.6 3.1 3.5 1.4 0.7 5.2 2.7 0.5 4.7 1.3 2.0 21.8 3.5 0.7 7.5 0.1 0.1 1.9 3.1 9.5 8.3 8.1 3.8 5.8 0.7 0.6 7.2 2.1 0.7 2.6 1.6 5.2 4.8 0.8 5.4 0.8 2.7 7.0 1.8 2.0 0.5 0.0 7.2 0.1 5.8 3.4 1.3 0.0 0.8 0.5 3.2 3.3 1.4 1.3 0.8 0.4 7.7 0.0 1.1 13.4 4.6 0.0 4.0 3.4 11.4 4.3 3.0 3.2 2.1 4.1 10.9 7.7 6.2 2.1 3.8 1.4 9.0 1.2 2.0 1.9 0.1 6.6 4.5 0.0 0.1 0.3 3.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.2 2.3 9.4 8.5 2.3 8.4 5.9 5.5 4.7 3.5 9.5 0.8 3.2 2.3 34.3 0.6 3.7 0.6 1.9 2.2 7.2 5.0 3.3 1.6 0.0 2.8 3.7 20.9 0.6 0.1 7.5 0.0 2.4 3.9 31.4 2.8 1.1 0.0 0.0 41.7 2.5 0.9 1.2 1.1 6.0 0.0 6.0 0.7 1.4 0.5 3.3 33.1 4.2 4.1 0.0 0.4 3.1 2.1 0.2 5.4 1.0 0.0 3.6 0.0 15.6 30.8 1.4 7.9 8.2 0.0 1.0 3.3 1.5 27.6 24.5 6.6 2.5 2.1 8.5 11.2 2.1 3.0 0.5 0.3 3.1 5.2 0.7 ZNF251 ENSG00000198169 "Zinc finger protein 251" Q9BRH9 8 144720907-144756417 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 31.6;Excitatory neurons: 49.1;Inhibitory neurons: 50.2;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 40.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018290 Approved Approved Nucleoplasm NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "HPA018290: AB_1859153" "unprognostic (1.16e-3)" "unprognostic (1.50e-1)" "unprognostic (1.47e-1)" "unprognostic (1.77e-1)" "unprognostic (6.87e-2)" "unprognostic (1.20e-1)" "unprognostic (4.26e-3)" "unprognostic (3.04e-2)" "unprognostic (2.53e-1)" "unprognostic (2.30e-1)" "unprognostic (5.75e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.42e-9)" "unprognostic (5.29e-2)" "unprognostic (1.60e-1)" "unprognostic (1.77e-1)" "unprognostic (2.33e-3)" 16.6 10.4 12.5 6.2 12.3 3.5 16.6 17.4 12.9 21.3 10.4 17.5 6.8 17.5 24.4 9.8 18.1 10.5 23.4 12.7 12.4 15.8 11.4 10.5 12.2 11.8 12.0 20.0 14.5 12.2 22.6 8.8 11.6 17.8 11.4 17.5 12.2 13.5 10.1 13.1 15.7 12.6 10.9 14.9 13.2 14.1 12.9 11.2 28.0 8.6 11.1 16.6 15.5 12.6 9.9 6.0 23.0 10.8 13.5 17.7 8.7 9.9 14.9 11.3 15.8 2.5 11.6 14.6 9.0 12.9 6.3 13.5 6.8 6.1 15.3 4.1 5.0 11.1 25.1 6.8 7.8 4.1 5.9 13.4 9.1 6.9 13.2 22.0 9.2 10.3 7.4 4.1 13.3 4.7 12.3 2.4 6.9 7.3 10.5 12.7 3.3 5.9 7.6 5.5 10.7 13.9 9.5 4.8 11.0 10.4 12.2 9.6 7.4 9.4 14.4 16.4 8.7 4.4 1.3 8.5 10.5 6.0 7.5 0.0 0.3 1.0 0.9 0.5 1.5 1.3 1.4 1.4 0.7 1.0 1.9 1.4 0.0 1.2 0.5 0.7 1.6 0.8 12.5 12.3 17.4 12.9 12.7 12.4 11.8 12.0 11.6 10.9 12.9 12.6 9.3 0.0 5.3 31.6 4.8 2.2 3.8 1.7 5.7 5.5 4.0 4.1 3.9 1.5 8.9 1.8 6.2 2.0 3.1 1.0 5.9 1.6 20.2 4.5 7.1 7.7 1.2 3.8 49.1 1.5 1.4 5.6 6.6 5.0 1.3 6.8 1.8 0.9 1.6 5.0 50.2 2.1 0.0 3.0 3.0 9.5 7.8 2.0 1.8 22.5 2.9 2.8 3.1 37.7 40.7 2.0 1.8 4.5 5.7 3.0 2.0 3.2 5.3 5.9 13.1 5.2 6.1 11.9 10.3 3.9 3.1 1.4 5.0 5.4 1.9 2.0 ZNF34 KOX32 ENSG00000196378 "Zinc finger protein 34" Q8IZ26 8 144772224-144787345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053925, HPA060755, HPA066805" Uncertain Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Cytosol "HPA053925: AB_2682311, HPA060755: AB_2684354, HPA066805: AB_2685725" "unprognostic (2.54e-1)" "unprognostic (3.50e-1)" "unprognostic (5.01e-2)" "unprognostic (7.60e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-2)" "unprognostic (3.26e-2)" "unprognostic (3.54e-2)" "unprognostic (2.85e-2)" "unprognostic (1.40e-2)" "unprognostic (9.84e-3)" "unprognostic (1.46e-1)" "unprognostic (3.46e-3)" "unprognostic (5.80e-2)" "unprognostic (2.09e-3)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" 9.3 4.2 8.5 2.8 9.3 3.3 8.6 12.8 10.5 10.4 8.1 10.2 2.2 9.1 4.7 3.8 10.0 3.6 5.8 8.6 9.4 6.0 5.0 5.5 3.9 9.0 9.0 10.8 5.1 6.2 9.7 4.7 9.6 7.5 3.6 12.4 4.5 7.3 6.3 8.1 5.6 6.6 8.4 4.9 5.6 6.4 9.0 5.4 8.2 6.4 3.0 9.1 7.4 10.9 2.1 3.0 5.7 4.7 4.7 4.8 1.4 1.8 4.1 4.6 3.8 0.8 3.3 3.1 3.4 4.9 2.6 2.0 3.4 3.9 3.6 2.9 2.8 6.3 5.4 2.7 4.3 1.8 3.4 4.8 4.4 3.5 7.7 5.0 3.2 2.0 4.2 2.6 4.1 5.0 3.8 2.7 3.9 4.7 3.3 3.3 2.1 4.1 2.6 2.2 5.6 4.0 4.1 3.0 3.1 3.6 3.2 2.3 2.0 4.3 3.9 3.4 3.9 3.4 1.2 3.9 3.1 2.7 5.1 8.2 6.7 12.9 6.6 6.5 5.7 7.2 6.2 7.8 10.2 7.4 4.3 6.5 1.0 6.1 16.3 4.8 5.1 4.8 8.5 9.3 12.8 10.5 8.6 9.4 9.0 9.0 9.6 8.4 9.0 10.9 17.2 6.4 5.1 3.3 5.5 3.7 2.8 3.9 5.2 7.8 4.6 9.1 3.0 1.5 3.9 0.0 0.0 2.7 2.4 1.4 5.9 3.0 10.6 3.2 7.7 7.9 0.0 1.7 4.8 1.3 3.1 6.7 1.1 4.9 5.1 3.8 2.9 2.1 1.8 13.5 6.2 1.7 6.1 1.2 4.5 7.9 7.2 4.1 3.6 2.8 8.2 6.2 2.1 3.0 8.2 1.1 3.2 4.9 2.7 2.0 2.8 2.3 1.1 9.1 6.6 8.5 7.5 16.4 9.9 8.4 4.8 2.3 4.9 4.2 2.3 0.9 RPL8 L8 ENSG00000161016 "Ribosomal protein L8" P62917 8 144789765-144792587 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 6599.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045095, HPA050165" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 170000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA045095: AB_2679213, HPA050165: AB_2681038" "unprognostic (2.52e-2)" "unprognostic (2.13e-2)" "unprognostic (2.09e-1)" "unprognostic (1.04e-2)" "unprognostic (1.67e-1)" "unprognostic (9.84e-2)" "prognostic unfavorable (7.22e-4)" "unprognostic (4.48e-2)" "unprognostic (1.41e-1)" "unprognostic (1.54e-1)" "unprognostic (9.28e-2)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "unprognostic (1.79e-2)" "unprognostic (1.77e-1)" "unprognostic (2.31e-1)" "unprognostic (4.13e-2)" 1100.4 864.4 197.2 397.5 201.1 1020.7 1162.7 197.3 361.6 1387.5 199.5 1138.7 688.7 1042.4 63.7 1406.6 1118.6 146.4 962.6 174.2 193.7 889.8 709.6 796.1 424.5 214.1 195.2 2192.7 2021.1 150.3 784.2 264.4 199.9 974.9 110.0 22.9 1320.1 201.8 1651.4 1800.7 885.7 115.6 222.7 918.6 1003.5 304.7 218.2 150.0 739.9 194.0 196.4 1099.7 1240.2 218.1 2486.1 2860.3 200.1 874.6 220.0 496.0 1913.2 1747.7 325.3 522.4 369.7 2518.8 1299.5 3296.6 2461.9 208.4 174.3 1470.7 263.8 609.1 95.7 1446.1 3218.7 1962.1 2166.5 1805.2 546.9 1299.9 1027.5 537.1 680.7 235.9 400.8 246.5 387.8 703.1 2695.3 742.2 226.0 6599.2 1862.9 1754.6 1865.3 674.7 3196.8 1806.5 1154.4 3160.7 280.1 1842.0 1215.9 2028.4 1677.7 899.2 2541.5 81.0 2093.2 1233.3 1573.7 689.8 2622.6 1454.9 2127.3 1344.2 1235.8 2856.3 1372.4 2117.5 968.7 534.8 1464.1 574.8 1160.0 1504.9 1934.6 2970.9 1937.9 1430.4 2051.1 2991.2 2181.6 1718.2 166.1 1469.4 1479.6 1129.7 2070.5 5473.9 197.2 201.1 197.3 361.6 174.2 193.7 214.1 195.2 199.9 222.7 218.2 218.1 2510.5 852.5 1309.5 28.7 4225.5 6439.6 7085.5 5724.6 4563.8 424.0 6122.9 9469.1 1049.0 1988.8 2513.8 1028.1 268.9 4313.8 1790.8 1780.8 4433.5 2429.1 891.2 1083.4 2465.0 2455.7 1698.3 2407.7 24.0 5851.2 6733.6 2161.3 1804.3 1452.8 1044.4 2390.5 2116.1 1309.7 3031.0 166.5 28.5 3563.5 1698.8 2811.4 5097.7 2782.3 3122.7 2281.9 3520.0 30.9 2951.5 1300.3 1607.7 16.1 32.8 3402.4 3311.1 1432.3 3168.7 6500.7 3930.7 4195.9 961.7 689.1 1078.1 2701.0 3865.8 591.8 583.4 5817.5 8224.4 4365.8 2704.6 3472.7 4291.2 7522.7 ZNF517 ENSG00000197363 "Zinc finger protein 517" Q6ZMY9 8 144798876-144811169 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Hep G2: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055337 Approved Nucleoplasm NA NA "Cluster 37: B-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "HPA055337: AB_2682788" "unprognostic (9.54e-3)" "unprognostic (4.72e-2)" "unprognostic (3.20e-2)" "unprognostic (3.06e-2)" "unprognostic (1.81e-1)" "unprognostic (1.55e-2)" "unprognostic (2.22e-2)" "unprognostic (3.13e-1)" "unprognostic (4.83e-2)" "unprognostic (9.64e-2)" "prognostic favorable (1.66e-4)" "unprognostic (1.83e-1)" "unprognostic (4.23e-2)" "unprognostic (2.75e-1)" "unprognostic (2.40e-1)" "unprognostic (1.38e-1)" "unprognostic (9.57e-2)" 2.9 5.9 2.4 2.1 2.0 1.0 3.2 1.9 3.2 5.5 0.4 4.8 2.2 6.8 0.4 3.3 5.5 2.0 3.2 3.2 0.7 4.2 3.6 2.6 2.3 1.8 1.6 7.2 3.5 1.8 5.0 1.4 2.2 5.0 0.3 2.2 4.2 1.0 6.3 6.3 3.4 0.6 0.9 3.4 3.7 4.0 2.0 1.1 4.8 0.8 0.9 4.9 4.0 2.3 1.7 3.2 5.2 5.1 0.8 1.5 2.7 1.4 0.4 0.3 0.2 1.0 1.9 0.9 3.6 0.5 2.2 1.7 0.2 0.6 0.7 3.8 1.4 2.2 2.0 11.7 1.9 0.5 2.2 1.1 1.3 0.2 1.0 2.9 1.2 2.7 2.6 1.4 0.9 2.8 2.3 1.3 3.6 3.5 3.5 3.2 1.6 0.8 0.5 2.1 2.3 6.6 4.3 1.7 1.7 2.5 4.2 2.0 1.5 3.5 5.3 1.8 1.6 2.2 0.4 0.7 3.7 0.9 2.9 0.1 0.3 0.0 0.5 0.7 0.3 1.4 0.4 0.3 0.3 0.1 0.3 0.3 0.1 0.3 0.4 0.1 0.6 0.4 2.4 2.0 1.9 3.2 3.2 0.7 1.8 1.6 2.2 0.9 2.0 2.3 1.8 0.0 0.5 1.3 1.2 0.5 5.8 0.9 0.6 3.9 1.6 1.3 3.3 2.8 1.1 0.0 8.4 0.8 1.2 0.8 1.9 0.8 1.3 1.8 1.5 1.5 1.2 0.8 0.9 0.5 0.7 1.7 1.1 1.3 0.0 2.2 2.2 2.3 1.5 3.3 1.3 1.5 2.0 2.2 0.5 0.0 0.9 1.4 0.0 1.0 0.5 2.5 4.1 1.5 0.6 0.9 0.3 1.2 0.9 1.6 1.3 3.3 0.8 3.6 0.0 1.8 1.5 4.3 3.0 0.9 1.1 0.4 1.5 2.2 0.9 4.1 ZNF7 "HF.16, KOX4" ENSG00000147789 "Zinc finger protein 7" P17097 8 144827464-144847509 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059090 Approved Approved Mitochondria NA NA "Cluster 42: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Mitochondria "HPA059090: AB_2683901" "unprognostic (1.11e-1)" "unprognostic (4.47e-3)" "unprognostic (1.93e-1)" "unprognostic (1.36e-2)" "unprognostic (2.52e-1)" "unprognostic (2.97e-1)" "unprognostic (8.42e-3)" "unprognostic (3.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (8.46e-8)" "unprognostic (1.15e-1)" "unprognostic (5.00e-1)" "unprognostic (5.43e-2)" "unprognostic (6.53e-2)" 18.4 14.1 10.4 10.7 11.0 14.4 18.3 18.6 12.8 20.2 10.7 18.2 10.4 18.0 15.2 14.8 17.5 10.5 14.3 10.5 9.8 18.3 15.5 14.5 15.0 11.6 10.8 19.4 17.4 15.3 16.8 14.3 11.1 20.5 12.7 13.9 16.4 13.6 26.6 21.1 17.2 12.7 9.0 21.7 15.2 17.0 11.2 15.9 19.3 17.5 15.6 18.3 17.2 13.4 16.7 22.2 21.4 21.1 17.9 27.2 19.6 17.4 22.0 23.1 19.7 11.4 20.9 23.1 19.9 19.0 12.6 14.2 19.5 25.4 25.1 15.4 16.2 41.3 30.6 13.3 20.7 12.1 18.5 26.1 30.3 18.1 44.2 22.4 14.5 19.2 41.9 16.1 26.0 27.3 33.0 13.1 21.8 22.0 26.6 22.6 19.0 18.4 16.1 22.6 21.0 25.6 38.1 21.6 21.3 20.4 26.1 19.1 16.4 17.3 30.9 13.2 16.9 13.0 9.9 25.0 18.0 15.4 21.7 34.3 10.7 10.9 13.5 10.0 16.9 18.1 15.4 12.0 12.2 17.4 20.1 13.8 10.4 16.6 19.2 9.6 16.3 9.2 10.4 11.0 18.6 12.8 10.5 9.8 11.6 10.8 11.1 9.0 11.2 13.4 11.9 19.2 11.6 6.2 16.4 7.0 18.2 12.7 8.6 34.2 9.1 8.0 11.4 7.2 11.3 3.7 29.2 17.3 16.6 6.6 5.9 14.1 18.4 6.3 10.4 10.6 9.6 15.6 11.3 11.2 12.9 14.7 10.2 7.7 3.8 16.7 15.0 8.2 9.1 28.6 10.7 9.1 6.1 9.0 11.1 4.9 17.7 10.2 8.8 3.7 12.9 20.0 22.6 10.6 11.4 13.7 5.6 15.8 7.8 18.6 12.4 7.1 9.2 30.1 6.6 19.3 10.4 44.1 26.7 9.1 9.2 19.4 16.9 19.8 10.2 13.8 COMMD5 "FLJ13008, HCaRG, HT002" ENSG00000170619 "COMM domain containing 5" Q9GZQ3 8 144841042-144853736 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046905 Supported Nucleoplasm,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "HPA046905: AB_2732535" "unprognostic (2.95e-2)" "unprognostic (7.62e-2)" "unprognostic (2.63e-1)" "unprognostic (1.16e-1)" "unprognostic (1.36e-1)" "unprognostic (9.13e-2)" "unprognostic (5.05e-3)" "unprognostic (6.82e-2)" "unprognostic (3.24e-1)" "unprognostic (9.35e-2)" "unprognostic (2.25e-1)" "unprognostic (7.97e-3)" "unprognostic (1.25e-2)" "unprognostic (8.58e-2)" "unprognostic (3.43e-1)" "unprognostic (2.02e-1)" "unprognostic (7.73e-3)" 17.0 22.9 16.6 11.9 17.0 21.2 15.7 18.1 19.7 14.9 15.6 15.6 12.1 16.1 9.7 20.1 14.2 11.3 18.9 16.2 16.3 18.7 23.2 15.1 16.2 18.1 16.9 12.8 16.7 14.5 17.7 11.0 17.5 16.4 6.8 3.8 15.5 10.7 18.2 16.8 14.9 8.8 17.3 21.9 16.4 11.2 17.2 11.3 16.4 11.4 10.6 15.9 14.3 18.7 32.8 38.3 17.9 24.2 21.8 17.4 16.0 18.5 19.7 30.9 24.2 23.0 25.1 22.3 40.4 22.6 17.9 21.7 22.5 30.6 13.2 29.6 31.7 47.1 35.3 38.8 28.8 16.0 39.6 23.1 27.6 21.2 15.7 15.0 24.2 7.9 34.2 39.8 25.2 59.4 14.6 16.8 27.1 45.6 75.3 18.8 20.4 34.8 30.2 28.3 41.6 36.6 30.9 18.5 27.4 11.9 36.3 29.7 22.4 23.1 45.9 33.3 36.8 16.6 19.2 21.3 32.5 29.7 30.5 66.1 84.3 76.6 55.8 72.4 49.8 60.7 42.4 54.9 74.2 54.1 41.6 46.7 52.3 69.2 47.0 26.8 71.2 70.1 16.6 17.0 18.1 19.7 16.2 16.3 18.1 16.9 17.5 17.3 17.2 18.7 27.8 12.8 15.0 8.5 27.5 27.8 20.4 46.4 11.4 12.3 22.8 23.9 10.9 21.5 25.0 16.5 12.5 35.8 39.0 26.4 39.2 46.4 3.5 19.6 16.4 27.6 19.9 14.1 6.2 40.1 23.8 22.7 13.7 18.6 24.8 15.6 25.7 19.0 70.0 11.8 7.7 16.8 34.6 31.4 27.6 2.5 18.6 34.2 26.6 5.6 37.2 22.3 38.1 6.6 9.5 50.0 18.4 23.3 20.3 42.7 29.8 44.6 28.2 15.2 13.1 16.0 24.6 12.1 17.2 18.4 30.0 33.1 27.0 28.7 18.9 28.5 ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Cytosol "HPA020853: AB_1859152" "unprognostic (1.16e-3)" "unprognostic (9.56e-2)" "unprognostic (2.63e-1)" "unprognostic (2.60e-3)" "unprognostic (1.03e-1)" "unprognostic (5.95e-3)" "unprognostic (3.73e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (7.37e-2)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "prognostic favorable (2.43e-7)" "unprognostic (2.23e-1)" "unprognostic (6.79e-2)" "unprognostic (5.82e-2)" "prognostic favorable (8.26e-4)" 4.7 3.9 3.2 3.3 3.2 2.9 5.6 10.5 4.7 9.7 2.3 6.9 4.8 7.4 2.8 6.4 7.6 3.3 4.9 2.4 4.5 7.6 4.0 5.1 3.0 3.0 3.2 9.7 4.9 6.0 7.3 5.5 3.3 7.5 3.6 7.9 6.0 5.2 4.8 10.9 5.2 4.2 1.5 5.5 4.9 4.5 3.3 4.5 10.0 5.8 3.3 6.3 8.6 3.4 5.1 2.9 13.4 11.1 6.8 5.9 4.3 5.6 6.4 9.4 7.7 2.4 3.9 12.0 9.8 6.5 3.8 6.6 5.3 4.8 6.0 3.8 7.8 10.8 14.9 3.5 2.0 1.8 3.6 3.9 6.5 5.6 4.5 7.2 3.9 7.1 8.6 11.5 7.9 6.8 12.6 4.1 4.0 6.0 12.5 14.4 5.9 5.0 7.8 3.7 13.2 10.1 11.8 4.4 5.3 5.3 6.3 6.1 5.1 9.2 8.8 7.3 5.3 5.6 5.1 8.0 4.7 6.2 4.1 3.2 5.1 5.8 10.5 2.7 8.1 10.3 7.7 5.8 6.6 9.7 8.9 7.3 2.9 6.0 3.7 2.6 11.7 4.5 3.2 3.2 10.5 4.7 2.4 4.5 3.0 3.2 3.3 1.5 3.3 3.4 5.8 12.8 3.0 10.7 10.7 5.5 3.2 7.5 10.2 8.4 4.3 6.6 4.3 1.5 3.9 5.5 0.0 2.3 18.6 2.4 3.9 7.5 7.4 5.1 6.0 5.5 4.2 1.7 11.9 1.9 1.3 5.2 2.6 4.9 2.5 6.3 5.0 2.1 1.7 8.4 17.5 1.9 12.2 2.2 8.0 3.0 4.1 3.0 5.4 4.7 2.0 3.3 5.2 11.1 7.8 2.6 1.0 5.3 8.2 3.3 3.7 3.4 5.0 9.9 13.1 4.1 6.1 14.3 8.7 4.4 5.5 1.9 10.9 4.9 3.4 2.3 ZNF16 KOX9 ENSG00000170631 "Zinc finger protein 16" P17020 8 144930358-144950888 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035782, HPA061835" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Nucleoli Nucleoplasm "HPA035782: AB_10603243, HPA061835: AB_2684621" "unprognostic (4.11e-2)" "unprognostic (1.51e-2)" "unprognostic (6.87e-2)" "unprognostic (2.45e-1)" "unprognostic (2.69e-1)" "prognostic favorable (2.39e-4)" "unprognostic (7.53e-3)" "unprognostic (1.10e-1)" "unprognostic (1.24e-1)" "unprognostic (8.50e-2)" "unprognostic (1.45e-1)" "unprognostic (2.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.70e-2)" "unprognostic (2.96e-1)" "unprognostic (9.75e-2)" "unprognostic (4.17e-3)" 4.6 3.6 4.6 2.4 4.7 2.6 6.3 4.4 5.0 6.0 5.9 6.5 4.7 6.2 6.9 5.9 7.1 5.7 4.4 4.5 4.4 5.3 3.9 3.7 3.2 4.2 4.2 11.0 7.5 8.6 4.0 3.9 4.3 5.4 4.7 5.1 4.6 5.6 8.3 9.3 4.8 5.5 4.5 3.4 5.0 7.5 4.8 4.4 7.0 8.3 3.9 5.7 6.0 4.6 4.5 3.9 7.7 4.2 6.4 9.0 5.5 4.0 8.9 8.0 7.2 3.1 4.5 7.1 5.2 5.2 4.3 3.5 5.4 8.9 7.2 3.1 4.5 8.2 4.4 4.5 10.7 3.0 4.6 10.9 8.8 5.1 13.2 7.9 4.4 5.3 5.7 4.7 6.4 6.2 6.1 3.0 4.7 6.9 8.8 7.5 4.5 4.5 6.8 6.7 6.4 4.7 8.5 5.1 6.9 5.8 9.5 5.6 4.7 3.6 7.5 4.3 4.5 3.4 3.1 6.4 4.1 4.0 5.8 2.6 3.0 2.2 4.9 2.9 5.6 2.8 3.8 4.5 4.8 4.4 3.8 3.5 0.4 9.2 3.0 2.5 5.8 3.2 4.6 4.7 4.4 5.0 4.5 4.4 4.2 4.2 4.3 4.5 4.8 4.6 3.6 3.2 4.4 4.9 3.4 2.7 6.9 6.8 5.2 11.4 4.3 2.9 3.7 5.7 3.1 9.2 12.5 5.9 7.0 3.2 1.9 7.3 10.3 2.0 3.5 3.7 4.2 3.0 6.8 4.4 3.6 3.8 5.1 3.9 7.0 9.4 5.0 4.5 3.6 6.7 6.3 5.6 6.1 3.5 2.4 3.7 6.2 2.1 1.8 6.5 5.4 6.2 7.2 6.6 7.2 3.6 4.9 6.4 3.2 4.2 10.6 4.8 3.4 25.1 0.0 3.4 4.0 13.6 18.1 4.5 4.5 5.5 5.1 6.6 5.4 5.5 C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA024812: AB_10599490, HPA026104: AB_10600875" "prognostic unfavorable (2.77e-4)" "unprognostic (6.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (8.95e-4)" "unprognostic (4.75e-2)" "unprognostic (3.51e-1)" "unprognostic (2.45e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" 16.5 42.1 32.3 13.1 32.1 18.2 24.8 33.5 41.7 17.7 28.3 21.7 13.1 20.4 27.1 19.5 22.8 16.5 22.3 32.0 33.1 18.7 17.1 15.0 18.2 33.3 34.3 40.7 20.8 34.0 5.6 21.1 32.8 18.8 33.4 24.6 16.4 24.2 16.9 17.4 10.2 19.6 32.4 12.2 11.5 13.1 32.7 19.3 33.2 26.0 18.4 18.8 8.9 33.3 28.3 32.7 45.8 22.7 51.3 35.5 17.2 16.6 41.7 42.0 23.3 9.2 39.2 30.3 55.3 40.5 19.5 22.4 67.5 41.2 45.3 15.0 48.4 38.1 32.1 11.5 53.1 30.6 15.1 41.0 60.4 43.0 96.8 34.5 28.1 44.9 75.4 26.3 46.1 42.4 86.3 12.3 31.8 89.1 55.2 51.2 14.9 46.6 44.1 16.3 44.1 39.1 44.3 39.3 39.0 26.1 41.1 29.1 13.8 27.5 37.3 24.2 37.8 21.7 16.9 72.2 65.9 47.0 55.1 1.0 13.7 8.7 16.3 17.4 18.4 13.4 16.2 17.8 19.6 13.3 21.3 15.6 1.4 28.2 16.0 18.4 12.6 16.3 32.3 32.1 33.5 41.7 32.0 33.1 33.3 34.3 32.8 32.4 32.7 33.3 67.8 28.9 27.2 4.9 34.8 44.4 32.8 31.9 24.5 48.3 52.8 47.9 18.4 45.8 33.8 25.8 31.3 36.9 45.3 180.5 62.6 79.5 5.6 49.9 55.1 50.2 35.3 17.5 5.7 64.9 40.2 41.7 20.9 53.0 21.5 58.5 37.1 66.8 28.7 50.5 6.0 36.4 14.2 21.5 21.2 5.6 37.9 23.0 16.0 7.5 32.3 61.2 45.3 4.0 6.0 55.3 37.7 38.7 20.4 48.1 22.1 66.1 26.6 54.5 26.3 32.8 37.9 26.2 34.8 25.4 42.9 24.9 23.6 94.9 53.0 28.5